BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3685c Length=476 Score E Sequences producing significant alignments: (Bits) Value gi|15610821|ref|NP_218202.1| cytochrome P450 137 [Mycobacterium ... 938 0.0 gi|31794856|ref|NP_857349.1| cytochrome P450 137 [Mycobacterium ... 937 0.0 gi|339633677|ref|YP_004725319.1| cytochrome P450 [Mycobacterium ... 937 0.0 gi|298527160|ref|ZP_07014569.1| cytochrome P450 137 cyp137 [Myco... 935 0.0 gi|340628658|ref|YP_004747110.1| putative cytochrome P450 137 CY... 932 0.0 gi|308371416|ref|ZP_07424918.2| cytochrome P450 137 cyp137 [Myco... 892 0.0 gi|308232531|ref|ZP_07416378.2| cytochrome P450 137 cyp137 [Myco... 854 0.0 gi|289748199|ref|ZP_06507577.1| cytochrome P450 137 cyp137 [Myco... 780 0.0 gi|240172249|ref|ZP_04750908.1| cytochrome P450 137A2 Cyp137A2 [... 722 0.0 gi|183985145|ref|YP_001853436.1| cytochrome P450 137A2 Cyp137A2 ... 704 0.0 gi|289759841|ref|ZP_06519219.1| LOW QUALITY PROTEIN: cytochrome ... 697 0.0 gi|167970837|ref|ZP_02553114.1| putative cytochrome P450 137 cyp... 613 2e-173 gi|120401690|ref|YP_951519.1| cytochrome P450 [Mycobacterium van... 501 1e-139 gi|284041826|ref|YP_003392166.1| cytochrome P450 [Conexibacter w... 270 4e-70 gi|284045204|ref|YP_003395544.1| cytochrome P450 [Conexibacter w... 257 3e-66 gi|342860591|ref|ZP_08717242.1| cytochrome P450 [Mycobacterium c... 255 1e-65 gi|54024144|ref|YP_118386.1| cytochrome P450 monooxygenase [Noca... 255 1e-65 gi|108802056|ref|YP_642253.1| cytochrome P450 [Mycobacterium sp.... 253 4e-65 gi|126438035|ref|YP_001073726.1| cytochrome P450 [Mycobacterium ... 251 3e-64 gi|296165665|ref|ZP_06848185.1| P450 heme-thiolate protein [Myco... 250 5e-64 gi|254823430|ref|ZP_05228431.1| cytochrome P450 family protein [... 249 7e-64 gi|343924792|ref|ZP_08764331.1| putative cytochrome P450 [Gordon... 249 1e-63 gi|262203253|ref|YP_003274461.1| cytochrome P450 [Gordonia bronc... 248 1e-63 gi|284041673|ref|YP_003392013.1| cytochrome P450 [Conexibacter w... 243 6e-62 gi|326381927|ref|ZP_08203620.1| cytochrome P450 [Gordonia neofel... 243 7e-62 gi|119718594|ref|YP_925559.1| cytochrome P450 [Nocardioides sp. ... 241 2e-61 gi|315446566|ref|YP_004079445.1| cytochrome P450 [Mycobacterium ... 241 2e-61 gi|296168352|ref|ZP_06850276.1| P450 heme-thiolate protein [Myco... 240 4e-61 gi|145221696|ref|YP_001132374.1| cytochrome P450 [Mycobacterium ... 239 5e-61 gi|296165650|ref|ZP_06848172.1| P450 heme-thiolate protein [Myco... 239 8e-61 gi|284044098|ref|YP_003394438.1| cytochrome P450 [Conexibacter w... 238 1e-60 gi|15607278|ref|NP_214650.1| cytochrome P450 138 [Mycobacterium ... 238 2e-60 gi|240168137|ref|ZP_04746796.1| putative cytochrome p450 138 [My... 238 2e-60 gi|169631766|ref|YP_001705415.1| cytochrome P450 [Mycobacterium ... 238 2e-60 gi|289747903|ref|ZP_06507281.1| cytochrome P450 138 [Mycobacteri... 238 2e-60 gi|296167326|ref|ZP_06849728.1| cytochrome P450 138 [Mycobacteri... 236 8e-60 gi|169977295|emb|CAQ18836.1| putative cytochrome P450 [Chondromy... 235 1e-59 gi|289760236|ref|ZP_06519614.1| cytochrome P450 138 [Mycobacteri... 234 3e-59 gi|183984401|ref|YP_001852692.1| cytochrome P450 138B1 Cyp138B1 ... 232 9e-59 gi|186684527|ref|YP_001867723.1| cytochrome P450 [Nostoc punctif... 232 1e-58 gi|169628518|ref|YP_001702167.1| putative cytochrome P450 [Mycob... 231 2e-58 gi|333920661|ref|YP_004494242.1| cytochrome P450 [Amycolicicoccu... 231 2e-58 gi|218437822|ref|YP_002376151.1| cytochrome P450 [Cyanothece sp.... 231 3e-58 gi|118467999|ref|YP_885605.1| cytochrome P450 monooxygenase [Myc... 229 9e-58 gi|183982980|ref|YP_001851271.1| cytochrome P450 135B6 Cyp135B6 ... 228 1e-57 gi|254777502|ref|ZP_05219018.1| cytochrome P450 monooxygenase [M... 228 2e-57 gi|118465972|ref|YP_884277.1| cytochrome P450 monooxygenase [Myc... 228 2e-57 gi|336459910|gb|EGO38822.1| cytochrome P450 [Mycobacterium avium... 228 2e-57 gi|340625595|ref|YP_004744047.1| putative cytochrome P450 135B1 ... 228 2e-57 gi|307153475|ref|YP_003888859.1| cytochrome P450 [Cyanothece sp.... 227 3e-57 >gi|15610821|ref|NP_218202.1| cytochrome P450 137 [Mycobacterium tuberculosis H37Rv] gi|15843303|ref|NP_338340.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|148663548|ref|YP_001285071.1| putative cytochrome p450 137 CYP137 [Mycobacterium tuberculosis H37Ra] 36 more sequence titles Length=476 Score = 938 bits (2424), Expect = 0.0, Method: Compositional matrix adjust. Identities = 476/476 (100%), Positives = 476/476 (100%), Gaps = 0/476 (0%) Query 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV Sbjct 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 Query 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA Sbjct 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 Query 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML Sbjct 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 Query 181 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA Sbjct 181 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 Query 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL Sbjct 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 Query 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA Sbjct 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 Query 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK Sbjct 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 Query 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR Sbjct 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 >gi|31794856|ref|NP_857349.1| cytochrome P450 137 [Mycobacterium bovis AF2122/97] gi|121639599|ref|YP_979823.1| putative cytochrome P450 137 cyp137 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224992095|ref|YP_002646784.1| putative cytochrome P450 137 [Mycobacterium bovis BCG str. Tokyo 172] gi|31620453|emb|CAD95896.1| PROBABLE CYTOCHROME P450 137 CYP137 [Mycobacterium bovis AF2122/97] gi|121495247|emb|CAL73733.1| Probable cytochrome P450 137 cyp137 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224775210|dbj|BAH28016.1| putative cytochrome P450 137 [Mycobacterium bovis BCG str. Tokyo 172] gi|341603620|emb|CCC66301.1| probable cytochrome P450 137 cyp137 [Mycobacterium bovis BCG str. Moreau RDJ] Length=476 Score = 937 bits (2423), Expect = 0.0, Method: Compositional matrix adjust. Identities = 475/476 (99%), Positives = 476/476 (100%), Gaps = 0/476 (0%) Query 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV Sbjct 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 Query 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA Sbjct 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 Query 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 AAIYGSGSMFVQEEP+HLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML Sbjct 121 AAIYGSGSMFVQEEPQHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 Query 181 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA Sbjct 181 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 Query 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL Sbjct 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 Query 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA Sbjct 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 Query 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK Sbjct 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 Query 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR Sbjct 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 >gi|339633677|ref|YP_004725319.1| cytochrome P450 [Mycobacterium africanum GM041182] gi|339333033|emb|CCC28762.1| putative cytochrome P450 137 CYP137 [Mycobacterium africanum GM041182] Length=476 Score = 937 bits (2422), Expect = 0.0, Method: Compositional matrix adjust. Identities = 475/476 (99%), Positives = 476/476 (100%), Gaps = 0/476 (0%) Query 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV Sbjct 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 Query 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA Sbjct 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 Query 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML Sbjct 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 Query 181 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 TVARSLMLDVI+KVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA Sbjct 181 TVARSLMLDVIIKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 Query 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL Sbjct 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 Query 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA Sbjct 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 Query 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK Sbjct 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 Query 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR Sbjct 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 >gi|298527160|ref|ZP_07014569.1| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis 94_M4241A] gi|298496954|gb|EFI32248.1| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis 94_M4241A] Length=476 Score = 935 bits (2417), Expect = 0.0, Method: Compositional matrix adjust. Identities = 475/476 (99%), Positives = 475/476 (99%), Gaps = 0/476 (0%) Query 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV Sbjct 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 Query 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA Sbjct 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 Query 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYV IIENSTRAAMHTWPVDRPFAML Sbjct 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVSIIENSTRAAMHTWPVDRPFAML 180 Query 181 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA Sbjct 181 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 Query 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL Sbjct 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 Query 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA Sbjct 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 Query 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK Sbjct 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 Query 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR Sbjct 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 >gi|340628658|ref|YP_004747110.1| putative cytochrome P450 137 CYP137 [Mycobacterium canettii CIPT 140010059] gi|340006848|emb|CCC46037.1| putative cytochrome P450 137 CYP137 [Mycobacterium canettii CIPT 140010059] Length=476 Score = 932 bits (2409), Expect = 0.0, Method: Compositional matrix adjust. Identities = 473/476 (99%), Positives = 473/476 (99%), Gaps = 0/476 (0%) Query 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV Sbjct 1 MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAV 60 Query 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA 120 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSD ALAKEVFTAPTDVLLGGEGVGPA Sbjct 61 AYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDPALAKEVFTAPTDVLLGGEGVGPA 120 Query 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML Sbjct 121 AAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAML 180 Query 181 TVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPA 240 TVARSLMLDVIVKVIFGVDDPEE RRLGRPFERLLNLGVSEQLTVRY LRRLGALRVWPA Sbjct 181 TVARSLMLDVIVKVIFGVDDPEEARRLGRPFERLLNLGVSEQLTVRYVLRRLGALRVWPA 240 Query 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL Sbjct 241 RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 Query 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA Sbjct 301 AGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVA 360 Query 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK Sbjct 361 AQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVK 420 Query 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR Sbjct 421 RCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 >gi|308371416|ref|ZP_07424918.2| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis SUMu003] gi|308372616|ref|ZP_07429284.2| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis SUMu004] gi|308373782|ref|ZP_07433648.2| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis SUMu006] 12 more sequence titles Length=453 Score = 892 bits (2305), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/453 (99%), Positives = 453/453 (100%), Gaps = 0/453 (0%) Query 24 VAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTM 83 +AAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTM Sbjct 1 MAAFAVRREHAPDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTM 60 Query 84 PILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKL 143 PILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKL Sbjct 61 PILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKL 120 Query 144 LTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEE 203 LTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEE Sbjct 121 LTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEE 180 Query 204 VRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADP 263 VRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADP Sbjct 181 VRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADP 240 Query 264 RLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDA 323 RLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDA Sbjct 241 RLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDA 300 Query 324 LRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIA 383 LRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIA Sbjct 301 LRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIA 360 Query 384 INRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREG 443 INRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREG Sbjct 361 INRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREG 420 Query 444 EFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 EFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR Sbjct 421 EFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 453 >gi|308232531|ref|ZP_07416378.2| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis SUMu001] gi|308369193|ref|ZP_07416910.2| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis SUMu002] gi|308372706|ref|ZP_07429584.2| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis SUMu005] 9 more sequence titles Length=433 Score = 854 bits (2206), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/433 (99%), Positives = 433/433 (100%), Gaps = 0/433 (0%) Query 44 LPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEV 103 +PAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEV Sbjct 1 MPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEV 60 Query 104 FTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENS 163 FTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENS Sbjct 61 FTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENS 120 Query 164 TRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQL 223 TRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQL Sbjct 121 TRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQL 180 Query 224 TVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESG 283 TVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESG Sbjct 181 TVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESG 240 Query 284 EQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVI 343 EQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVI Sbjct 241 EQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVI 300 Query 344 NETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFL 403 NETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFL Sbjct 301 NETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFL 360 Query 404 GTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLV 463 GTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLV Sbjct 361 GTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLV 420 Query 464 PRRGTRVRFRPAR 476 PRRGTRVRFRPAR Sbjct 421 PRRGTRVRFRPAR 433 >gi|289748199|ref|ZP_06507577.1| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis T92] gi|289688786|gb|EFD56215.1| cytochrome P450 137 cyp137 [Mycobacterium tuberculosis T92] Length=394 Score = 780 bits (2013), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/394 (100%), Positives = 394/394 (100%), Gaps = 0/394 (0%) Query 83 MPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRK 142 MPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRK Sbjct 1 MPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRK 60 Query 143 LLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE 202 LLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE Sbjct 61 LLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE 120 Query 203 EVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRAD 262 EVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRAD Sbjct 121 EVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRAD 180 Query 263 PRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPD 322 PRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPD Sbjct 181 PRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPD 240 Query 323 ALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHII 382 ALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHII Sbjct 241 ALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHII 300 Query 383 AINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLRE 442 AINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLRE Sbjct 301 AINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLRE 360 Query 443 GEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 GEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR Sbjct 361 GEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 394 >gi|240172249|ref|ZP_04750908.1| cytochrome P450 137A2 Cyp137A2 [Mycobacterium kansasii ATCC 12478] Length=472 Score = 722 bits (1864), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/441 (86%), Positives = 401/441 (91%), Gaps = 0/441 (0%) Query 34 APDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAI 93 +PD + PPGLPAPR FR AFAAAYAVAYL GGERRMLRLIRRYGPIMTMPIL+LGDVAI Sbjct 14 SPDVIRRPPGLPAPRPFRTAFAAAYAVAYLVGGERRMLRLIRRYGPIMTMPILTLGDVAI 73 Query 94 VSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAAL 153 VSD AL KEVFTAP DVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAAL Sbjct 74 VSDPALVKEVFTAPADVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAAL 133 Query 154 DRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFER 213 + YVPIIE+STRAAM +WPVDRPFA+L AR+LMLDVIVKV+FGV DP+EVRRLGRPFER Sbjct 134 NGYVPIIEDSTRAAMRSWPVDRPFALLPAARALMLDVIVKVVFGVQDPDEVRRLGRPFER 193 Query 214 LLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLS 273 LLNLGVSEQLTVRYALRRLG LRVWP+RARA EIDDVV+ LIA+RR DP L E+ D+L+ Sbjct 194 LLNLGVSEQLTVRYALRRLGTLRVWPSRARAFREIDDVVLPLIARRRNDPGLTEQRDILA 253 Query 274 LLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVG 333 LL+ ARG+ GE LSDSEIRDDLITL+LAGHETTATTLAW FDLLLHHP+ALRRVRAEAV Sbjct 254 LLMCARGDDGEWLSDSEIRDDLITLMLAGHETTATTLAWVFDLLLHHPEALRRVRAEAVS 313 Query 334 GGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEH 393 G E FTTAVINETLRVRPPAPLTARVAAQP IG Y V+AGTRIVVHIIAINR+ VY+H Sbjct 314 GAEDFTTAVINETLRVRPPAPLTARVAAQPFRIGDYLVDAGTRIVVHIIAINRNPGVYDH 373 Query 394 PHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPE 453 P+EFRPERFLG RPQTYAWVPFGGGVKRCLGA FSMREL+TVLHVLLREGEF+AVDD PE Sbjct 374 PNEFRPERFLGVRPQTYAWVPFGGGVKRCLGAAFSMRELVTVLHVLLREGEFSAVDDRPE 433 Query 454 RIVRRSIMLVPRRGTRVRFRP 474 RIVRRSIML PR GTRVRFRP Sbjct 434 RIVRRSIMLAPRHGTRVRFRP 454 >gi|183985145|ref|YP_001853436.1| cytochrome P450 137A2 Cyp137A2 [Mycobacterium marinum M] gi|183178471|gb|ACC43581.1| cytochrome P450 137A2 Cyp137A2 [Mycobacterium marinum M] Length=456 Score = 704 bits (1818), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/440 (84%), Positives = 390/440 (89%), Gaps = 0/440 (0%) Query 35 PDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIV 94 P AL PPGLPAPR R FAAAYAVAYL GGERRMLRLIRRYGPIMTMPILSLGDVAIV Sbjct 11 PPALRRPPGLPAPRRLRTVFAAAYAVAYLVGGERRMLRLIRRYGPIMTMPILSLGDVAIV 70 Query 95 SDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALD 154 SD AL KEVFTAP DVLLGGEGVGPAAAIYG+GSMFVQEEPEHLRRRKLLTPPLHG AL Sbjct 71 SDPALVKEVFTAPPDVLLGGEGVGPAAAIYGAGSMFVQEEPEHLRRRKLLTPPLHGTALG 130 Query 155 RYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERL 214 RYVPIIE STRAAM WPVDRPF +L AR+LMLDVIVKVIFGVDDP+EVRRLGRPFERL Sbjct 131 RYVPIIEESTRAAMRDWPVDRPFELLGAARALMLDVIVKVIFGVDDPDEVRRLGRPFERL 190 Query 215 LNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSL 274 L+LGVSEQLTVRYALRR GALRVWP RARA EI+DVVM LIAQRR+D E+ D+L L Sbjct 191 LDLGVSEQLTVRYALRRAGALRVWPQRARAYREIEDVVMPLIAQRRSDLGRTEQRDILGL 250 Query 275 LVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGG 334 L+SARG+ GEQLSD EIRDDLITL+LAGHETTATTLAW FDLLLHHPDALRRV+ EA GG Sbjct 251 LISARGDDGEQLSDQEIRDDLITLMLAGHETTATTLAWVFDLLLHHPDALRRVQEEAEGG 310 Query 335 GEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHP 394 E FTTAVINETLRVRPPAP TARVAA+P +GGY ++ GTRIVVH+IAINR+ +VYE P Sbjct 311 TETFTTAVINETLRVRPPAPFTARVAARPFRLGGYLIDPGTRIVVHMIAINRNPDVYEQP 370 Query 395 HEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPER 454 + FRPERFLGTRPQTYAWVPFGGG KRCLGA FSMREL+TVLHVLLREG+FTAVD+ PER Sbjct 371 NRFRPERFLGTRPQTYAWVPFGGGAKRCLGAAFSMRELVTVLHVLLREGQFTAVDEAPER 430 Query 455 IVRRSIMLVPRRGTRVRFRP 474 IVRRSIML PR GTRVRFRP Sbjct 431 IVRRSIMLAPRHGTRVRFRP 450 >gi|289759841|ref|ZP_06519219.1| LOW QUALITY PROTEIN: cytochrome P450 137 cyp137 [Mycobacterium tuberculosis T85] gi|289715405|gb|EFD79417.1| LOW QUALITY PROTEIN: cytochrome P450 137 cyp137 [Mycobacterium tuberculosis T85] Length=385 Score = 697 bits (1798), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/354 (99%), Positives = 353/354 (99%), Gaps = 1/354 (0%) Query 123 IYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTV 182 IYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTV Sbjct 33 IYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTV 92 Query 183 ARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARA 242 ARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARA Sbjct 93 ARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARA 152 Query 243 RANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAG 302 RANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAG Sbjct 153 RANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAG 212 Query 303 HETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQ 362 HETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQ Sbjct 213 HETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQ 272 Query 363 PLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRC 422 PLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPF GGVKRC Sbjct 273 PLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPF-GGVKRC 331 Query 423 LGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 LGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR Sbjct 332 LGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 385 >gi|167970837|ref|ZP_02553114.1| putative cytochrome P450 137 cyp137 [Mycobacterium tuberculosis H37Ra] Length=309 Score = 613 bits (1581), Expect = 2e-173, Method: Compositional matrix adjust. Identities = 309/309 (100%), Positives = 309/309 (100%), Gaps = 0/309 (0%) Query 168 MHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRY 227 MHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRY Sbjct 1 MHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRY 60 Query 228 ALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLS 287 ALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLS Sbjct 61 ALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLS 120 Query 288 DSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETL 347 DSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETL Sbjct 121 DSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETL 180 Query 348 RVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRP 407 RVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRP Sbjct 181 RVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRP 240 Query 408 QTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRG 467 QTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRG Sbjct 241 QTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRG 300 Query 468 TRVRFRPAR 476 TRVRFRPAR Sbjct 301 TRVRFRPAR 309 >gi|120401690|ref|YP_951519.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] gi|119954508|gb|ABM11513.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1] Length=453 Score = 501 bits (1290), Expect = 1e-139, Method: Compositional matrix adjust. Identities = 262/424 (62%), Positives = 315/424 (75%), Gaps = 1/424 (0%) Query 54 FAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLG 113 F YA A+ GG+ + +++RRYGP++ +P+L G V V+D+ALAK+VFT DVLLG Sbjct 16 FGGLYAAAFGMGGQAIVAQMVRRYGPVVALPVLGFGKVVAVADAALAKQVFTENPDVLLG 75 Query 114 GEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPV 173 GEGVGPAAAIYG SMFV EEP HLRRR+LLTPPLHG L YVPIIE+STR+AM TWPV Sbjct 76 GEGVGPAAAIYGPRSMFVLEEPGHLRRRRLLTPPLHGELLGSYVPIIESSTRSAMATWPV 135 Query 174 DRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLG 233 RP ML AR L LDVIV+V+FGV DPE V R G+PF LL+L +SE+ VRYALRR G Sbjct 136 GRPMRMLDAARELTLDVIVQVVFGVHDPESVARFGKPFHELLDLALSEETPVRYALRRFG 195 Query 234 ALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRD 293 ALR W + AN ID++V+ LIA+RR+DP ER D+LS+L ++ + GE LSD+EIRD Sbjct 196 ALRRWGRLSDANRRIDELVLPLIAERRSDPLSAERADILSMLANSHTDDGETLSDNEIRD 255 Query 294 DLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPA 353 DLITLVLAGHETTATTL+W DLLLHHP AL RVRAEAV G +T AVI ETLR+RP A Sbjct 256 DLITLVLAGHETTATTLSWLIDLLLHHPRALARVRAEAVSGDTGYTEAVIAETLRLRPAA 315 Query 354 PLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWV 413 P+T R+ P +G Y +E TRIV+ + INR+ + Y P EFRPERFLG+RP YAW+ Sbjct 316 PITGRMTTGPYRLGDYTLEPDTRIVLLLDVINRNPDTYPQPDEFRPERFLGSRPHPYAWI 375 Query 414 PFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPER-IVRRSIMLVPRRGTRVRF 472 PFGGGVKRC+GA F+MREL T LH +LREGE V PE +R + +LVPR GTRVRF Sbjct 376 PFGGGVKRCIGAAFAMRELTTTLHTVLREGELEPVSARPETPPLRAAPVLVPRDGTRVRF 435 Query 473 RPAR 476 PAR Sbjct 436 TPAR 439 >gi|284041826|ref|YP_003392166.1| cytochrome P450 [Conexibacter woesei DSM 14684] gi|283946047|gb|ADB48791.1| cytochrome P450 [Conexibacter woesei DSM 14684] Length=460 Score = 270 bits (690), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 160/403 (40%), Positives = 212/403 (53%), Gaps = 3/403 (0%) Query 72 RLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFV 131 R RR+G + T+ + G++ + +D AL K FTA L GEG P + G S+ V Sbjct 37 RCQRRHGDLFTVRVHHFGNIVVPADPALIKRTFTASPVALHSGEG-SPLGPVLGPNSLLV 95 Query 132 QEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVI 191 +E HLR+RKLL PP HG + RY +IE TR + WP DR F + + L I Sbjct 96 TDEDVHLRQRKLLLPPFHGQRMQRYEQLIEAVTREEIARWPRDREFPVAPSTMRITLRAI 155 Query 192 VKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDV 251 + +FG + +R+L L LG + LT Y LG W R ++D V Sbjct 156 LLAVFGARG-DALRQLEELLPPLTTLGSALALTP-YLQHDLGPRSPWGRFKRLRAQVDAV 213 Query 252 VMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLA 311 L+AQ R DP L ER DVL+LLV A E G + D+EIRD L+T++ AGHETTA LA Sbjct 214 CDELMAQARRDPDLAERSDVLALLVQATYEDGAPMRDAEIRDQLMTMLAAGHETTAAQLA 273 Query 312 WAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRV 371 W + L HPD L R+ AEA GG A I E R RP T R+ +P +GG+ + Sbjct 274 WTVERLRRHPDVLERLVAEADAGGRELRDATIREVQRQRPVIMFTTRLVKEPFELGGFML 333 Query 372 EAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRE 431 GTRI + + ++ P F PERFLG +P+TYAW+PFGGGV+RC+GA F+ E Sbjct 334 PPGTRIALAGALTHYDERLFADPFAFSPERFLGRKPETYAWLPFGGGVRRCIGAAFAHME 393 Query 432 LITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRP 474 + VL +L PER+ R I P G R P Sbjct 394 MDVVLRTILLTYALAPTSSPPERMKFRGIAHTPASGGLARVTP 436 >gi|284045204|ref|YP_003395544.1| cytochrome P450 [Conexibacter woesei DSM 14684] gi|283949425|gb|ADB52169.1| cytochrome P450 [Conexibacter woesei DSM 14684] Length=481 Score = 257 bits (657), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 174/479 (37%), Positives = 241/479 (51%), Gaps = 22/479 (4%) Query 6 LASPAALTDPKRCASVVGVAAFAVRREHAPDAL---GGPPGLPAPRGFRAAFAAAYAVAY 62 LAS +A T +++G A + A D L PP +P PR + + + + Sbjct 2 LASASATTHADDAHALIGEAPPSPAGPLAADDLRPIALPPAIPLPRALQTLRFSVRQIEF 61 Query 63 LAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAA 122 + R + R G ++ V + S K +FTA D G P Sbjct 62 VFRYRRLLGETFRFRG------VVDDEFVVLTSHPDHVKSLFTAKPDDAPSLTGESPLRP 115 Query 123 IYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTV 182 I G S+ P H+R+RKLL PP HG A+ RY +I + +WPV +P + Sbjct 116 IVGPNSVLTAIGPRHMRQRKLLLPPFHGEAVQRYAEMIAAVADREIDSWPVGKPIRLAPS 175 Query 183 ARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVR---YALRRLGALRVWP 239 +++ LDVI+ IFGV+ E R + V L+VR L R P Sbjct 176 TQAITLDVIMAGIFGVEGLPEKGTPERGLRDAIRWAVG--LSVRPEAQLFELLNIRREEP 233 Query 240 A--RARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLIT 297 A R +D V ALI QRR +R D+LSLL+ A E G L+D E+RD+L+T Sbjct 234 AGPLKRLLDHVDRFVYALIDQRREAGDAAQRADILSLLLEATDEDGTPLTDRELRDELLT 293 Query 298 LVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTT------AVINETLRVRP 351 LVLAGHETTA +LAWAF+ L+ P A R+R + G AF A I+ET+R RP Sbjct 294 LVLAGHETTANSLAWAFERLVRTPAAYDRLRDISRSGDAAFADEDGWIEATIHETMRSRP 353 Query 352 PAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYA 411 P+ R +P +G YRV AGT + + I+ ++ +VY P FRPERFLG RP TY Sbjct 354 VIPMIGRRVTRPWELGEYRVPAGTSVAMSILLLHHREDVYPDPFAFRPERFLGVRPGTYT 413 Query 412 WVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRV 470 W+PFGGG++RCLGA +M E VL + R + AVD PE R++ ++P+ G RV Sbjct 414 WIPFGGGIRRCLGAALAMAEQRVVLRAIARRTDLVAVDAAPEHARHRNVTMIPQEGARV 472 >gi|342860591|ref|ZP_08717242.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] gi|342132246|gb|EGT85487.1| cytochrome P450 [Mycobacterium colombiense CECT 3035] Length=404 Score = 255 bits (652), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 152/408 (38%), Positives = 224/408 (55%), Gaps = 14/408 (3%) Query 70 MLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSM 129 M R RYG TM +L G + +VS +++FTA ++ L GE + G S+ Sbjct 1 MERAAARYGDTFTMKLLREGPIVMVSHPDAVRQIFTASPELALAGEANRILLPVVGRNSV 60 Query 130 FVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLD 189 + + H +R+LL P G L Y+ + A M WP P + ++L L+ Sbjct 61 LLLDRDAHKEQRRLLMPAFRGNHLQNYMSTMTAIVEAEMAGWPRGVPIRLHPRMQALTLE 120 Query 190 VIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARAN---- 245 VI+ ++FG++ E++ RL + +R+L L +A+ ++ L + P + R Sbjct 121 VILHLVFGLERGEKMDRLRQALQRMLALTT-------HAVAQMFLLVLGPQKLRTALTNR 173 Query 246 --TEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGH 303 E+D ++ I RR L +R DVLS+L+ A E G +SD EIRD+L+TL+LAGH Sbjct 174 FLAEVDRLLHDEITTRRRQADLDDRTDVLSMLLKAEHEDGNPMSDKEIRDELVTLLLAGH 233 Query 304 ETTATTLAWAFDLLLHHPDALRRVRAEA-VGGGEAFTTAVINETLRVRPPAPLTARVAAQ 362 ETTA+ LAWA + ++ HPD R+ AE G G+++ AV+ ETLR+RP L +R + Sbjct 234 ETTASGLAWAVERIIRHPDVHSRLIAETHSGDGQSYVDAVVKETLRMRPVLALVSRRLTE 293 Query 363 PLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRC 422 P+ + G+ + AG ++ I ++R +VY P FRPERFL R TY W+PFGGGV+RC Sbjct 294 PMELDGFSLPAGVKVAPSIYLMHRRPDVYPDPERFRPERFLENRAGTYTWIPFGGGVRRC 353 Query 423 LGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRV 470 LGA F+ E+ VL L VD + E I RRSI VP RGT V Sbjct 354 LGATFAECEMRIVLGALFSTTRVRPVDVKSEPIHRRSITHVPGRGTTV 401 >gi|54024144|ref|YP_118386.1| cytochrome P450 monooxygenase [Nocardia farcinica IFM 10152] gi|54015652|dbj|BAD57022.1| cytochrome P450 monooxygenase [Nocardia farcinica IFM 10152] Length=451 Score = 255 bits (652), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 171/427 (41%), Positives = 229/427 (54%), Gaps = 24/427 (5%) Query 60 VAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTA------PTDVLLG 113 VA+ A G R RL RRYG T + G V ++SD A K +FTA DV LG Sbjct 19 VAFAASGTRSWHRLHRRYGSAFTASLPRFGRVVVLSDPAEVKALFTAGPELVDNIDVNLG 78 Query 114 GEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPV 173 G GSMF H R RKLLTPP HG L Y +IE +TRA +WP Sbjct 79 --------QFLGPGSMFSLNGEHHRRHRKLLTPPFHGKRLTVYETMIEEATRAEAASWPQ 130 Query 174 DRPFAMLTVARSLMLDVIVKVIFGV--DDPEEVRRLGRPFERLLNLGVS-EQLTVRYALR 230 R F + + LDVI++ +FG ++ +++R L R++ L S L V L Sbjct 131 GREFPTMDSWMRITLDVILRAVFGAQGNEADQLRDL---LPRMVVLASSLAMLPVPGPL- 186 Query 231 RLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSE 290 LG + W A D++V LI ADP L ER DVL+++V AR + G ++ E Sbjct 187 -LGRVGPWARYAAHRRRYDEIVGRLIDHAAADPHLDERDDVLAMMVQARYDDGAAMTRGE 245 Query 291 IRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVR 350 I D+L+TL+ AGHETTATTLAW + L HP+ LRR+ AEA GG A + E R R Sbjct 246 IADELLTLLAAGHETTATTLAWTIERLRRHPELLRRLVAEADEGGHELREATVLEVQRTR 305 Query 351 PPAPLTAR-VAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQT 409 P LTAR V A+ L +G + + G R++V I ++ + E++ + F P+RFLG RP T Sbjct 306 PVIELTARTVRAETLPLGRWTLPKGQRVLVSIRLMHDNEELFPNARAFDPDRFLGVRPGT 365 Query 410 YAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVP-RRGT 468 Y W+PFGGG +RC+GA F+ E+ VL LLRE ER R + + P R+G Sbjct 366 YRWIPFGGGARRCIGAAFATMEMNVVLRTLLREFTLAPTAAPAERRHFRGVAVAPARKGR 425 Query 469 RVRFRPA 475 V +R A Sbjct 426 AVVYRRA 432 >gi|108802056|ref|YP_642253.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119871208|ref|YP_941160.1| cytochrome P450 [Mycobacterium sp. KMS] gi|108772475|gb|ABG11197.1| cytochrome P450 [Mycobacterium sp. MCS] gi|119697297|gb|ABL94370.1| cytochrome P450 [Mycobacterium sp. KMS] Length=449 Score = 253 bits (647), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 166/442 (38%), Positives = 231/442 (53%), Gaps = 22/442 (4%) Query 35 PDALGGPPGLPAP---RGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDV 91 P A+ PP L AP +G AFA V+++A RR+GP+ + I G Sbjct 14 PRAVNLPPALRAPMPLQGIAYAFARRQLVSWMA----------RRHGPVFRIHIPMFGRT 63 Query 92 AIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGA 151 +V+D LAK++F APTD + G + I G GS+F + EH RRR+LLTPPLHG Sbjct 64 VMVADPQLAKQLFMAPTDAV--GNIQPNLSRILGPGSVFALDGAEHKRRRRLLTPPLHGK 121 Query 152 ALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDP--EEVRRLGR 209 ++ Y + E T WP RPF L + L+VI++ +FG D +E+RR+ Sbjct 122 SVKNYEKLFEEETLRESANWPEGRPFETLEPMMRITLNVILRAVFGADGEKLDELRRIIP 181 Query 210 PFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERH 269 P+ + LG S + G W A D+V+ LI + RADPR GER Sbjct 182 PW---VTLG-SRLAVIPSPPTTFGRWTPWGRLADYRRRYDEVIDRLIDEVRADPRFGERD 237 Query 270 DVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRA 329 DVL+LL+ + E G ++S SEI D+L+TL+ AGHETTA+TL WAF+ + HPD L ++ A Sbjct 238 DVLALLLRSTYEDGTEMSRSEIADELLTLLAAGHETTASTLGWAFERISRHPDVLAKLVA 297 Query 330 EAVGGGEAFTTAVINETLRVRPPAPLTAR-VAAQPLTIGGYRVEAGTRIVVHIIAINRSA 388 EA + A I E R R R V A +G + + G IVV + I+ A Sbjct 298 EAATDDNEYRQATIFEVQRNRTVIDFAGRHVYAPTFELGEWVIPRGYSIVVALAEIHEQA 357 Query 389 EVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAV 448 E Y P F PERF+G+RP VPFGGG +RC+GA F+ E+ VL +LR Sbjct 358 EDYVDPERFSPERFVGSRPSPLVHVPFGGGTRRCIGAVFANVEMDIVLRTVLRHFVIEPT 417 Query 449 DDEPERIVRRSIMLVPRRGTRV 470 E++ R + P+ G +V Sbjct 418 TAPGEKVHSRGVAYTPKAGGQV 439 >gi|126438035|ref|YP_001073726.1| cytochrome P450 [Mycobacterium sp. JLS] gi|126237835|gb|ABO01236.1| cytochrome P450 [Mycobacterium sp. JLS] Length=449 Score = 251 bits (640), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 165/445 (38%), Positives = 231/445 (52%), Gaps = 22/445 (4%) Query 35 PDALGGPPGLPAP---RGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDV 91 P A+ PP L AP +G AFA V+++A RR+GP+ + I G Sbjct 14 PRAVNLPPALRAPMPLQGIAYAFARRQLVSWMA----------RRHGPVFRIHIPMFGRT 63 Query 92 AIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGA 151 +V+D LAK++F APTD + G + I G GS+F + EH RRR+LLTPPLHG Sbjct 64 VMVADPQLAKQLFMAPTDEV--GNIQPNLSRILGPGSVFALDGAEHKRRRRLLTPPLHGK 121 Query 152 ALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDP--EEVRRLGR 209 ++ Y + E T WP RPF L + L+VI++ +FG D +E+RR+ Sbjct 122 SVKNYEKLFEEETLRESANWPEGRPFETLEPMMRITLNVILRAVFGADGEKLDELRRIIP 181 Query 210 PFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERH 269 P+ + LG S + G W A D+V+ LI + RADPR GER Sbjct 182 PW---VTLG-SRLAVIPSPPTTFGRWTPWGRLADYRRRYDEVIDRLIDEVRADPRFGERD 237 Query 270 DVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRA 329 DVL+LL+ + E G ++S SEI D+L+TL+ AGHETTA+TL WAF+ + HP+ L ++ A Sbjct 238 DVLALLLRSTYEDGTEMSRSEIADELLTLLAAGHETTASTLGWAFERISRHPEVLAKLVA 297 Query 330 EAVGGGEAFTTAVINETLRVRPPAPLTAR-VAAQPLTIGGYRVEAGTRIVVHIIAINRSA 388 EA + A I E R R R V A + + + G IVV + I+ A Sbjct 298 EAATDDNEYRQATIYEVQRNRTVIDFAGRHVYAPTFELSEWVIPRGYSIVVALAEIHEQA 357 Query 389 EVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAV 448 E Y P F PERF+G+RP VPFGGG +RC+GA F+ E+ VL +LR Sbjct 358 EDYVDPERFSPERFVGSRPSPLVHVPFGGGTRRCIGAVFANVEMDIVLRTVLRHFAIEPT 417 Query 449 DDEPERIVRRSIMLVPRRGTRVRFR 473 E++ R + P+ G +V R Sbjct 418 TAPGEKVHSRGVAYTPKAGGQVTLR 442 >gi|296165665|ref|ZP_06848185.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898982|gb|EFG78468.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=455 Score = 250 bits (638), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 162/432 (38%), Positives = 218/432 (51%), Gaps = 17/432 (3%) Query 41 PPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALA 100 PPG P+ VA L R + L RR+G T+ + +G ++SD L Sbjct 14 PPGPTLPK-------VVQGVAVLTARHRIVAALGRRWGSAFTVNLPIIGQAVVISDPVLI 66 Query 101 KEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPII 160 K++FT D+L +G +++G GS F + EHLRRRKLL PP HG + Y I+ Sbjct 67 KDLFTTSPDLLGRASNLG---SVFGPGSTFSLDGAEHLRRRKLLVPPFHGRRMAGYETIV 123 Query 161 ENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE--EVRRLGRPFERLLNLG 218 E WP+ R F L + L+ I++ +FG E E+R L P+ L Sbjct 124 EEEVLRETSDWPMGREFETLPSMMRITLNAILRTVFGAQGSELDELRELLPPWVAL---- 179 Query 219 VSEQLTVRYALRR-LGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVS 277 S + LRR LG W AR D+V+ +LIAQ RA ER DVL+LL++ Sbjct 180 ASRMAILPPRLRRDLGPFSPWGRVARYRRRYDEVIASLIAQARAHTGDRERTDVLALLLA 239 Query 278 ARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEA 337 AR E G +SD + D+L+TL+ AGHETTATTLAWA + L HP L R+ AE GG Sbjct 240 ARYEDGSPISDGHVGDELLTLLAAGHETTATTLAWAVERLRRHPQLLERLVAEVDAGGSQ 299 Query 338 FTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEF 397 A I E R RP T+R+ + +G + + ++ + S Y F Sbjct 300 LAQATIWEVQRTRPVIEGTSRLTRARIRLGPWVIPEHHAVLTSVALTQDSEANYVDAATF 359 Query 398 RPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVR 457 P+RFL P Y W+P+GGGV+RC+GA F+ E+ L LLRE EF DD PER Sbjct 360 NPDRFLDHPPDNYTWIPYGGGVRRCIGAAFANMEMNVTLRTLLREFEFIPTDDPPERRHS 419 Query 458 RSIMLVPRRGTR 469 R I P RG R Sbjct 420 RGIANAPARGGR 431 >gi|254823430|ref|ZP_05228431.1| cytochrome P450 family protein [Mycobacterium intracellulare ATCC 13950] Length=404 Score = 249 bits (636), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 147/403 (37%), Positives = 225/403 (56%), Gaps = 4/403 (0%) Query 70 MLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSM 129 M R RYG TM ++ G + +VS +++FT+P +++L GE + G S+ Sbjct 1 MDRAAARYGDTFTMKLVGEGPIVMVSHPDAVRQIFTSPPELMLAGEANRILQPVVGQNSV 60 Query 130 FVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLD 189 + + H +R+LL P G L Y+ + +A + WP P + ++L L+ Sbjct 61 LLLDRDAHREQRRLLMPAFRGNQLQSYMSTMTAIAQAEIARWPRGVPVRLHPRMQALTLE 120 Query 190 VIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARA-RANTEI 248 VI+ ++FG++ + + RL + +R L L + ++ L +G ++ A + ++ Sbjct 121 VILHLVFGLERGQSMDRLRQALQRTLVLTTNG--AAQFFLLLVGPRKMRTALIHKLLADV 178 Query 249 DDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTAT 308 D ++ IA R L R DVLS+L+ AR E G +SD EIRD+LITL+LAGHETTA+ Sbjct 179 DRLLHEEIATPRRQADLDTRTDVLSMLLKARHEDGNPMSDQEIRDELITLLLAGHETTAS 238 Query 309 TLAWAFDLLLHHPDALRRVRAEA-VGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIG 367 LAWA + ++ HPDA R+ EA G+ + AV+ ETLR+RP L +R +P+ + Sbjct 239 GLAWAVERIIRHPDAHSRLIEEAHADDGQRYVDAVVKETLRMRPVLALVSRRLTEPMEVD 298 Query 368 GYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANF 427 G+ + AG ++ I ++R ++Y P +FRPERFL R TY W+PFGGGV+RCLGA F Sbjct 299 GFSLPAGVKVAPSIYLMHRRPDIYPDPKQFRPERFLDNRAGTYTWIPFGGGVRRCLGATF 358 Query 428 SMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRV 470 + E+ VL + VD + E I RRSI VP RGT V Sbjct 359 AECEMRIVLGAMFTTMRVRPVDAKSEPIHRRSITQVPGRGTTV 401 >gi|343924792|ref|ZP_08764331.1| putative cytochrome P450 [Gordonia alkanivorans NBRC 16433] gi|343765299|dbj|GAA11257.1| putative cytochrome P450 [Gordonia alkanivorans NBRC 16433] Length=436 Score = 249 bits (635), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 156/401 (39%), Positives = 221/401 (56%), Gaps = 11/401 (2%) Query 76 RYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEP 135 R+G T+ + G ++SD++LA+E+FTA V+ +G I G+GS+F E Sbjct 41 RHGTAFTVHLPVFGRAVVISDASLARELFTAGDKVINIQPNLG---RILGAGSIFSLEGR 97 Query 136 EHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVI 195 EH RRKLLTPPLHG + Y I+E RA TWPV+ FA + + L+VI++ + Sbjct 98 EHRARRKLLTPPLHGKRMKTYEQIVEEEVRAETSTWPVETEFASMEPMMRITLNVILRAV 157 Query 196 FGV--DDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVM 253 FG +D E +RR+ P ++ +G S TV R L A+ R E ++ Sbjct 158 FGAVGEDLENLRRIIPP---MVTVG-SRAATVPNLPRVLRAVDPNHRYERMRAEGKALLG 213 Query 254 ALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWA 313 LI + R DPRL ER D+L+L++ +R + G + D EI D+L+T++ AGHETT TTLAWA Sbjct 214 DLITRSRNDPRLEERDDILALMLRSRYDDGASMGDDEIGDELMTMLAAGHETTGTTLAWA 273 Query 314 FDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTAR-VAAQPLTIGGYRVE 372 F+ L HP+ L R+ AE GG + A I ET R RP AR V A L +G +R+ Sbjct 274 FERLRRHPEVLGRLVAEVDEGGTEYRHATILETQRSRPVIDFAARYVVADQLELGEWRIP 333 Query 373 AGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMREL 432 G ++V I ++ + + P F P RFLGT P AW+PFGGG +RC+GA F+ E+ Sbjct 334 RGYNVMVSIALLHDDSREFTDPERFDPTRFLGTAPSP-AWLPFGGGTRRCIGAAFATMEM 392 Query 433 ITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFR 473 L +L + E D ER R + P RG R+ R Sbjct 393 DVTLRTILSDFELLPTDARAERWFSRGVAYAPARGGRIAVR 433 >gi|262203253|ref|YP_003274461.1| cytochrome P450 [Gordonia bronchialis DSM 43247] gi|262086600|gb|ACY22568.1| cytochrome P450 [Gordonia bronchialis DSM 43247] Length=440 Score = 248 bits (634), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 169/426 (40%), Positives = 233/426 (55%), Gaps = 21/426 (4%) Query 56 AAYAVAYLAGGERRMLRLI-RRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGG 114 A V ++A RR+LR RR G ++ + G I+SD LAK++FTA V Sbjct 26 AIAGVGFIAS-RRRVLRFWQRRLGDTFSLDLPIFGSCVIISDPTLAKQLFTAGDKV---- 80 Query 115 EGVGPAAA-IYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPV 173 V P + G GS+F E +H RRKLLTPPLHG + Y IIE T A + TWP Sbjct 81 HNVQPNLGRVLGDGSVFSLEGNQHRLRRKLLTPPLHGKRIRTYESIIEEETLAEISTWPT 140 Query 174 DRPFAMLTVARSLMLDVIVKVIFGV--DDPEEVRRLGRPFERLLNLGVSEQLTVRY---A 228 DR FA L + L+VI++ +FG D +++RR+ P L+ G S T+ Sbjct 141 DRTFATLEPMMRITLNVILRAVFGAAGTDLDDLRRIIPP---LVEAG-SRAATLPPLPPV 196 Query 229 LRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSD 288 LRR+ R TE V+ LIA+ R D L +R D+L+LLVS+R + G +SD Sbjct 197 LRRVDPYHRLAIR---RTEYQRVIGDLIARSRDDANLADRDDILALLVSSRYDDGSPMSD 253 Query 289 SEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLR 348 ++I D+L+TL+ AGHETTATTLAWAF+ L +P AL R+ AE GG + AVI+E R Sbjct 254 ADIADELLTLLAAGHETTATTLAWAFERLSRNPGALDRLVAEVDEGGSQWRHAVISEVQR 313 Query 349 VRPPAPLTAR-VAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRP 407 RP L R V A L +G +R+ G ++V I ++ + V+ P F P RF+ P Sbjct 314 SRPVIDLAGRHVVADALELGPWRIPRGRNVIVAISLLHDDSRVFTDPERFDPSRFIDATP 373 Query 408 QTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRG 467 + AW+PFGGG +RC+GA F+ E+ VL ++RE ER R + PRRG Sbjct 374 -SAAWLPFGGGTRRCIGAAFATMEMEVVLRTVMRELVVEPTTARSERWHSRGVAYAPRRG 432 Query 468 TRVRFR 473 R+ R Sbjct 433 GRIAVR 438 >gi|284041673|ref|YP_003392013.1| cytochrome P450 [Conexibacter woesei DSM 14684] gi|283945894|gb|ADB48638.1| cytochrome P450 [Conexibacter woesei DSM 14684] Length=462 Score = 243 bits (619), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 170/443 (39%), Positives = 241/443 (55%), Gaps = 13/443 (2%) Query 34 APDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAI 93 APD PPG PR + ++ GE R RYG + T+ + V + Sbjct 5 APDTRSLPPGPTGPRVLTVSRFLLQPTRFV--GECR-----ERYGRLFTIRLSPGRTVVV 57 Query 94 VSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAAL 153 +D+A+AKEVFT +L GEG + G S+ + + PEHLR+R+L+ PP HG + Sbjct 58 AADAAVAKEVFTGDPALLHAGEGNVVLRPLLGPRSVLLLDGPEHLRQRRLMLPPFHGERM 117 Query 154 DRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFER 213 Y + + WPV PFA+ +++ L+VI++V+FGV++P V +L P R Sbjct 118 RGYGERMRAIADRHVAQWPVGEPFAVQRSMQAITLEVILRVVFGVEEPARVAQLSAPLRR 177 Query 214 LLNLGVSEQLTVRYALRRLGALRV---WPARARANTEIDDVVMALIAQRRADPRLGE--R 268 LL+ + L R R W R +D ++ IA RRA+ G R Sbjct 178 LLDSTEQPWRLLALQLTRSEGARPRTPWGRVRRLLAPVDAMIYEEIAARRAELESGRPTR 237 Query 269 HDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVR 328 D+L+LL+SAR E + L+D+E+RD+L+TL+LAGHETTAT L W + + HP+ L R+ Sbjct 238 DDILTLLLSARDEDDQPLTDAELRDELMTLLLAGHETTATALTWTLERITRHPEVLARLE 297 Query 329 AEAVG-GGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRS 387 AE G G +A+ AVI ETLR+RP P R PLT GG+ + AG I +I I+R Sbjct 298 AEVGGEGADAYLDAVIKETLRLRPVVPAVVRKLQAPLTFGGWDLPAGVNIAPNIWLIHRD 357 Query 388 AEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTA 447 +Y P FRPERFL P TY W+PFGGG++RCLGA+F++ E+ VL +L Sbjct 358 PALYPEPEAFRPERFLDRTPGTYEWLPFGGGIRRCLGASFALYEMRMVLSTILERTRLAP 417 Query 448 VDDEPERIVRRSIMLVPRRGTRV 470 D PE++ RR + P G RV Sbjct 418 TTDAPEQVTRRFVTFSPASGGRV 440 >gi|326381927|ref|ZP_08203620.1| cytochrome P450 [Gordonia neofelifaecis NRRL B-59395] gi|326199353|gb|EGD56534.1| cytochrome P450 [Gordonia neofelifaecis NRRL B-59395] Length=446 Score = 243 bits (619), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 171/445 (39%), Positives = 237/445 (54%), Gaps = 28/445 (6%) Query 41 PPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALA 100 PPG PR + A +L G R + RL RRYG +T+ + + GD ++SD A+A Sbjct 15 PPGPHRPRAVQGA-------EFLVGRRRALQRLARRYGDAVTLALPAFGDAVLISDPAMA 67 Query 101 KEVFTAPTDVLLGGEGVGPAAA-IYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPI 159 K++ A +DV+ V P I G GSMF + +H RRRKLLTPPLHG + Y I Sbjct 68 KQLCMAKSDVV---ANVRPNLGRILGGGSMFALDADDHRRRRKLLTPPLHGKRIKAYEEI 124 Query 160 IENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDP--EEVRRLGRPFERLLNL 217 + A TWP+ RPF L + L+VI++ +FG D + +R L P L+ Sbjct 125 VAEEFAAESATWPIGRPFPTLEPMMRITLNVILRAVFGADGMRLDALRELMPP---LVTH 181 Query 218 GVSEQLTVRYALRRLGALRVWPARARANTE---IDDVVMALIAQRRADPRLGERHDVLSL 274 G +LT L +G + R R E D VV+ LI + RADP+L +R D+L+L Sbjct 182 G--SRLTTLPDLPGIGG--SFNPRNRFAAERAAYDAVVVPLIREARADPQLADRADILAL 237 Query 275 LVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGG 334 +V + + G ++D+EI D+L+TL+ AGHETTATTLAWA + L HP L + AEA Sbjct 238 MVQSSYDDGSSMTDAEISDELLTLLAAGHETTATTLAWAMERLSRHPAILADLAAEADSD 297 Query 335 GEAFTTAVINETLRVRPPAPLTAR-VAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEH 393 A I+E R RP L R V A L +G YR+ G ++V I ++ + + Sbjct 298 ENTLRIATIHEVQRSRPVIDLFGRHVIADSLELGPYRIPKGYNVIVGISLLHDDSREFAD 357 Query 394 PHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPE 453 P F PERF+G RP AW+PFGGG +RC+G+ F+ E+ VL L R + E Sbjct 358 PERFDPERFVGARPGQ-AWLPFGGGTRRCIGSAFAHMEMDVVLRELFRSFTVQPTTAKDE 416 Query 454 RIVRRSIMLVPRRGTRV---RFRPA 475 R R + P RG RV R RP+ Sbjct 417 RWHSRGVAYAPARGGRVTLSRTRPS 441 >gi|119718594|ref|YP_925559.1| cytochrome P450 [Nocardioides sp. JS614] gi|119539255|gb|ABL83872.1| cytochrome P450 [Nocardioides sp. JS614] Length=464 Score = 241 bits (615), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 154/404 (39%), Positives = 217/404 (54%), Gaps = 11/404 (2%) Query 73 LIRRYGPIMTMPILSLG-DVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFV 131 L R+YG T+ + G + + AKE+F +V G+ G I G S+ + Sbjct 60 LHRKYGDAFTVRLAPGGRPLVFFTRPEHAKEIFAGDPEVFHAGKANGILGPIMGEHSLLL 119 Query 132 QEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVI 191 Q+ EH R RKLL P +G AL Y ++ RA + W + F L +L L+VI Sbjct 120 QDSREHKRARKLLMPAFNGHALREYQALVTEVARAEVGGWRSGQEFRALDRMNALTLEVI 179 Query 192 VKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYA-LRRLGALRVWPARARANTEIDD 250 ++V+FGV D + RL + +N+ + L Y L+R G W A E+D Sbjct 180 LRVVFGVTDEARLARLRPRVNKTVNISPAILLGWGYPWLQRFGP---WKATVDNQRELDR 236 Query 251 VVMALIAQRRADPRLGERHDVLSLLV--SARGESGEQLSDSEIRDDLITLVLAGHETTAT 308 ++ A I RR L ER DVLS L+ GESG++LSD+E+RD L+TL+LAGHETTA+ Sbjct 237 LMYAEIRDRRTATDLAERTDVLSRLILQGDSGESGDRLSDTELRDQLVTLLLAGHETTAS 296 Query 309 TLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGG 368 L+WA P L R + A GG + F AV+ E +R+ P P+ R +P TI G Sbjct 297 ALSWALYETGRDPGLLARCQRAAAGGDDDFLEAVLKEAMRLHPIIPMVVRTLMEPATIAG 356 Query 369 YRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFS 428 + + GT + II ++ + + P FRPERFLG P W+PFGGGV+RCLGA FS Sbjct 357 WDLPRGTTVGPSIIIAHQREDNHPDPDVFRPERFLGQNPPANTWIPFGGGVRRCLGAGFS 416 Query 429 MRELITVLHVLLREGEFTAVD-DEPERIVRRSIMLVPRRGTRVR 471 + E + VL + + A+ DEP+ R+I VPRRGTR+R Sbjct 417 LMEGVAVLREVFAAYDVEALGRDEPK---VRNITSVPRRGTRIR 457 >gi|315446566|ref|YP_004079445.1| cytochrome P450 [Mycobacterium sp. Spyr1] gi|315264869|gb|ADU01611.1| cytochrome P450 [Mycobacterium sp. Spyr1] Length=444 Score = 241 bits (615), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 150/405 (38%), Positives = 215/405 (54%), Gaps = 9/405 (2%) Query 72 RLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFV 131 +++RRYG + TM + G +V+D ALAK++F A TD + G + + GSGS+F Sbjct 44 QVVRRYGDVFTMTLPVFGKTVLVTDPALAKQLFMANTDDV--GNIQPNLSRVLGSGSVFA 101 Query 132 QEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVI 191 + +H RRKLLTPP HG ++ Y I E T +WP +PF L + L+ I Sbjct 102 LDGTDHRLRRKLLTPPFHGKSIKNYERIFEEETLREAASWPEGQPFETLEPMMRITLNAI 161 Query 192 VKVIFGVDDP--EEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEID 249 ++ +FG D +E+RR+ P+ + LG S + R G W AR D Sbjct 162 LRAVFGADGAHLDELRRIIPPW---VTLG-SRLAVLPTPHRTYGRFSPWGRLARYRRRYD 217 Query 250 DVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATT 309 +V+ LI +ADP R DVL+LL+ + E G +S +I D+L+TL+ AGHETTA T Sbjct 218 EVIGRLIDAVQADPNFESRDDVLALLLRSTYEDGSSMSRQDIGDELLTLLAAGHETTAAT 277 Query 310 LAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTAR-VAAQPLTIGG 368 L W F+ + HPD L R++AEA G + AVI ET RVR R V A +G Sbjct 278 LGWVFERISRHPDVLARLQAEADTDGNEYRQAVILETQRVRTVIDFAGRHVYAPTFELGE 337 Query 369 YRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFS 428 + + G IVV I ++ + Y P +F P+RF+G RP T + +PFGGG +RC+GA F+ Sbjct 338 WVIPQGYSIVVAIGQVHHREQDYLDPEDFDPQRFVGQRPSTLSHIPFGGGTRRCVGAVFA 397 Query 429 MRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFR 473 E+ VL +LR E++ R + P G RV R Sbjct 398 NVEMDIVLRTVLRHFTIETTTAPGEKMHSRGVAYTPDDGGRVVMR 442 >gi|296168352|ref|ZP_06850276.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896783|gb|EFG76416.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=436 Score = 240 bits (612), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 154/409 (38%), Positives = 216/409 (53%), Gaps = 11/409 (2%) Query 75 RRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEE 134 RRYG + T+ + +G + ++D A K VF V GE + + G S+ V +E Sbjct 19 RRYGSVFTLRVAGMGTLVYLADPADVKTVFAGDPRVFHAGEANSILSGLLGDTSLLVIDE 78 Query 135 PEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKV 194 H RR+L+ PP H A+ R ++ A + TWPV FA + L+VI++ Sbjct 79 DVHRDRRRLMLPPFHRDAVARQAGLMAEIAAANIATWPVGANFAAAPKMAEITLEVILRT 138 Query 195 IFGVDDPEEVRRLGRPFERLLNLGVSEQLTV-RYALRRLGALRVWPARARANTEIDDVVM 253 + G DP + L RLL++G L + + AL+R R W R E D ++ Sbjct 139 VIGATDPARLAALRAIMPRLLSVGPWATLALAKPALQRY---RPWRGLRRTMAEADRLLY 195 Query 254 ALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWA 313 A IA+RRADP + ER DVL++LV A + G +SD E+RD L+TL++AGH+TTA L+WA Sbjct 196 AEIAERRADPGVAERTDVLAMLVRA-DDGGRTMSDRELRDQLMTLLVAGHDTTANGLSWA 254 Query 314 FDLLLHHPDALRRVRAEAVGGG------EAFTTAVINETLRVRPPAPLTARVAAQPLTIG 367 + L HPD L R A A G + + A++ ETLRVRP RV +P + Sbjct 255 LERLTRHPDVLARAVAAAEAGAAGDPAGDEYLDALVKETLRVRPVVFDVGRVLTEPADVA 314 Query 368 GYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANF 427 GYR+ AG + I ++ SA VY PH F P+R LG W PF GG +RCLGA F Sbjct 315 GYRLPAGVMVAPGIGLVHTSAAVYPDPHRFDPDRMLGATLSPTTWFPFSGGNRRCLGAGF 374 Query 428 SMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 +M E+ VL +LR E ER + ++LVP RG R+R R R Sbjct 375 AMVEMRVVLREILRRVELDTTAAPAERQRLKFVVLVPHRGARIRLRALR 423 >gi|145221696|ref|YP_001132374.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] gi|145214182|gb|ABP43586.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK] Length=428 Score = 239 bits (611), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 149/405 (37%), Positives = 214/405 (53%), Gaps = 9/405 (2%) Query 72 RLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFV 131 +++RRYG + TM + G +V+D ALAK++F A TD + G + + GSGS+F Sbjct 28 QVVRRYGDVFTMTLPVFGKTVLVTDPALAKQLFMANTDDV--GNIQPNLSRVLGSGSVFA 85 Query 132 QEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVI 191 + +H RRKLLTPP HG ++ Y I E T +WP +PF L + L+ I Sbjct 86 LDGTDHRLRRKLLTPPFHGKSIKNYERIFEEETLREAASWPEGQPFETLEPMMRITLNAI 145 Query 192 VKVIFGVDDP--EEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEID 249 ++ +FG D +E+RR+ P+ + LG S + R G W AR D Sbjct 146 LRAVFGADGAHLDELRRIIPPW---VTLG-SRLAVLPTPHRTYGRFSPWGRLARYRRRYD 201 Query 250 DVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATT 309 +V+ LI +ADP R DVL+LL+ + E G +S +I D+L+TL+ AGHETTA T Sbjct 202 EVIGRLIDAVQADPNFESRDDVLALLLRSTYEDGSSMSRQDIGDELLTLLAAGHETTAAT 261 Query 310 LAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTAR-VAAQPLTIGG 368 L W F+ + HPD L R++AEA G + AVI ET RVR R V A +G Sbjct 262 LGWVFERISRHPDVLARLQAEADTDGNEYRQAVILETQRVRTVIDFAGRHVYAPTFELGE 321 Query 369 YRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFS 428 + + G IVV I ++ + Y P +F P+RF+G RP T + +PFGGG +RC+GA F+ Sbjct 322 WIIPQGYSIVVAIGQVHHREQDYLDPEDFDPQRFVGQRPSTLSHIPFGGGTRRCVGAVFA 381 Query 429 MRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFR 473 E+ VL + R E++ R + P G RV R Sbjct 382 NVEMDIVLRTVFRHFTIETTTAPGEKMHSRGVAYTPDDGGRVVMR 426 >gi|296165650|ref|ZP_06848172.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899021|gb|EFG78505.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=461 Score = 239 bits (610), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 150/415 (37%), Positives = 221/415 (54%), Gaps = 12/415 (2%) Query 68 RRMLRLI-RRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPA-AAIYG 125 +R+++L+ +R+GP+ + + G ++SD AL K++F P V GV P + G Sbjct 33 KRLMQLMGKRFGPVYSARLPLFGPAIVISDPALIKQLFQTPATV---ARGVEPNLDVVLG 89 Query 126 SGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARS 185 GSMF + H RRRKLL PP HG + Y +IE TR + TWP F +L Sbjct 90 KGSMFGLQGDTHRRRRKLLVPPFHGNRMRAYESLIEEETRNEIATWPQGAEFPVLPSTMR 149 Query 186 LMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRR-LGALRVWPARARA 244 + L+ I++ +FG ++ L +++ LG +L + + L LG W R Sbjct 150 ITLNAILRAVFGAQG-AQLDALRELMPKIVTLG--SRLALIHPLHHDLGPWSPWGRYLRL 206 Query 245 NTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHE 304 + D +V LIA+ +DP LGER DVL+L++ AR + G +S S+I D+L+TL+ AGHE Sbjct 207 RRQFDGIVTNLIAEAESDPDLGERTDVLALMLEARYDDGAAMSHSDIADELLTLLAAGHE 266 Query 305 TTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTAR-VAAQP 363 TTAT+LAWA + L HP+ L R+ E G A I E R RP AR V A Sbjct 267 TTATSLAWAIERLRRHPEVLSRLVDEIDAGQTGLLQATIYEVQRTRPVIDGAARQVIAPA 326 Query 364 LTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCL 423 + +G + + G ++V+I + + V+ F P+RF P +++W+PFGGG +RCL Sbjct 327 MPLGQWVIPQGYTVLVNISGTHNNDAVFADADRFNPDRFRDGVPDSHSWIPFGGGTRRCL 386 Query 424 GANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTR--VRFRPAR 476 GA F+ E+ VL +LRE + E+ R I PRRG R V RP R Sbjct 387 GAAFANMEMNVVLRTVLREYQLVPTTAPAEKWHSRGIAYAPRRGGRALVYRRPNR 441 >gi|284044098|ref|YP_003394438.1| cytochrome P450 [Conexibacter woesei DSM 14684] gi|283948319|gb|ADB51063.1| cytochrome P450 [Conexibacter woesei DSM 14684] Length=448 Score = 238 bits (608), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 149/403 (37%), Positives = 209/403 (52%), Gaps = 7/403 (1%) Query 71 LRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMF 130 +R+ RRYG TM + + S L K+V T +V G P A+ G S+ Sbjct 45 VRMHRRYGEPFTMRVPGFSPSLVFSSPELVKQVVTGKPNVFHAGLANRPLKAVLGRWSLL 104 Query 131 VQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDV 190 + HL++RKLL PP HG L Y +I +WPV PF + ++L L+V Sbjct 105 TLDRGPHLQQRKLLLPPFHGERLQAYGDLIRELAEREAASWPVGTPFRVAERMQALTLEV 164 Query 191 IVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDD 250 I+ V+FG+ D L R L++ A R LG R+ +D Sbjct 165 ILDVVFGITDESRKDDLRRLLPPLVDSSRHVVFWGSIANRNLGPFRLRETFETRRDAVDA 224 Query 251 VVMALIAQRRADP--RLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTAT 308 ++ A IA RR P L R D+LS+L+ A E G + D E+RD+L+TLV+AGHETTAT Sbjct 225 LLYAEIADRRRVPSGELAARSDILSMLIEATHEDGTPMGDGELRDELMTLVMAGHETTAT 284 Query 309 TLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGG 368 L WA DLLL +P L R+RA + + A E LR+RP P RV +P+ IG Sbjct 285 ALTWAMDLLLRNPAVLGRMRANP---DDEYVRATCQEILRIRPVVPFVGRVVTEPVRIGA 341 Query 369 YRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLG-TRPQTYAWVPFGGGVKRCLGANF 427 V AG ++ I + +V+ P FRPERF+G + +Y W+PFGGGV+RC+GA+F Sbjct 342 TEVPAGAGLIASIGLTHHREDVFPQPQVFRPERFVGESDVPSYGWLPFGGGVRRCIGASF 401 Query 428 SMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRV 470 + EL T+L VL + AV PE + + LVP RG ++ Sbjct 402 AQFELETILRVLAQSPVRLAV-RRPEPVRATGVTLVPGRGVKL 443 >gi|15607278|ref|NP_214650.1| cytochrome P450 138 [Mycobacterium tuberculosis H37Rv] gi|15839517|ref|NP_334554.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551] gi|31791314|ref|NP_853807.1| cytochrome P450 138 [Mycobacterium bovis AF2122/97] 69 more sequence titles Length=441 Score = 238 bits (607), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 156/443 (36%), Positives = 228/443 (52%), Gaps = 16/443 (3%) Query 34 APDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAI 93 AP + PP + P+ F+ +A++ R + R +RRYG T IL G V + Sbjct 10 APPVVRLPPAVRGPKLFQG-------LAFVVSRRRLLGRFVRRYGKAFTANILMYGRVVV 62 Query 94 VSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAAL 153 V+D LA++VFT+ + L G + ++GSGS+F + +H RRR+LL PP HG ++ Sbjct 63 VADPQLARQVFTSSPEEL--GNIQPNLSRMFGSGSVFALDGDDHRRRRRLLAPPFHGKSM 120 Query 154 DRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE--EVRRLGRPF 211 Y IIE T WP + FA L + L+ I++ IFG E E+RRL P+ Sbjct 121 KNYETIIEEETLRETANWPQGQAFATLPSMMHITLNAILRAIFGAGGSELDELRRLIPPW 180 Query 212 ERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDV 271 + LG S + R G L W A + D V+ LI RADP +R DV Sbjct 181 ---VTLG-SRLAALPKPKRDYGRLSPWGRLAEWRRQYDTVIDKLIEAERADPNFADRTDV 236 Query 272 LSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEA 331 L+L++ + + G +S +I D+L+TL+ AGHETTA TL WAF+ L HPD L + E Sbjct 237 LALMLRSTYDDGSIMSRKDIGDELLTLLAAGHETTAATLGWAFERLSRHPDVLAALVEEV 296 Query 332 VGGGEAFTTAVINETLRVRPPAPLTARVAAQPL-TIGGYRVEAGTRIVVHIIAINRSAEV 390 GG A I E R R AR P+ +G + + G I+++I I+ +V Sbjct 297 DNGGHELRQAAILEVQRARTVIDFAARRVNPPVYQLGEWVIPRGYSIIINIAQIHGDPDV 356 Query 391 YEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDD 450 + P F P+R++G++P +AW+PFGGG +RC+GA F+ E+ VL +LR Sbjct 357 FPQPDRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLETTTA 416 Query 451 EPERIVRRSIMLVPRRGTRVRFR 473 ER R + P+ G RV R Sbjct 417 AGERSHGRGVAFTPKDGGRVVMR 439 >gi|240168137|ref|ZP_04746796.1| putative cytochrome p450 138 [Mycobacterium kansasii ATCC 12478] Length=441 Score = 238 bits (607), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 154/409 (38%), Positives = 221/409 (55%), Gaps = 13/409 (3%) Query 70 MLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSM 129 M RL RRYG + T+ I G V +V D LA++VFT D L G + ++GSGS+ Sbjct 39 MRRLARRYGNVFTLNIPIYGRVVVVGDPQLARQVFTTSPDEL--GNIQPNLSRLFGSGSV 96 Query 130 FVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLD 189 F + +H RRR+LL PP HG ++ +Y IIE T WP PFA L + L+ Sbjct 97 FALDGDDHRRRRRLLAPPFHGKSIKKYEAIIEEETLRETARWPQGEPFATLPSMMHITLN 156 Query 190 VIVKVIFGVDDPE--EVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTE 247 I++ +FG D E E+RRL P+ + LG S + R G W A + Sbjct 157 AILRAVFGADGAELDELRRLIPPW---VTLG-SRLAAMPKPKRNYGRYSPWGRLAEYRRQ 212 Query 248 IDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTA 307 D V+ LI + R+DP +R DVL+L++ + E G +S +I D+L+TL+ AGHETTA Sbjct 213 YDAVLDTLIDRERSDPDFADRTDVLALMLRSTYEDGSVMSRKDIGDELLTLLAAGHETTA 272 Query 308 TTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTAR-VAAQPLTI 366 TLAWAF+ L HP L + AEA GG+ A I E R R AR + + + Sbjct 273 ATLAWAFERLTRHPQLLAALVAEADAGGDELRQATILEVQRARTVIDFAARHIYSDVYRL 332 Query 367 GGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGAN 426 G + + G I+V+I I+ + +V+ P F P+R+L ++P +AW+PFGGG +RC+GA Sbjct 333 GEWAIPRGDSIIVNIGQIHDNPDVFPDPQRFDPQRYLASKPSAFAWIPFGGGTRRCVGAA 392 Query 427 FSMRELITVLHVLLREG--EFTAVDDEPERIVRRSIMLVPRRGTRVRFR 473 F+ E+ VL +LR E T DE R R + +P+ G R+ R Sbjct 393 FANMEMDVVLRTVLRHFVIETTTAPDEKWRC--RGVAYIPKDGGRIVVR 439 >gi|169631766|ref|YP_001705415.1| cytochrome P450 [Mycobacterium abscessus ATCC 19977] gi|169243733|emb|CAM64761.1| Probable cytochrome P450 [Mycobacterium abscessus] Length=467 Score = 238 bits (607), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 152/434 (36%), Positives = 218/434 (51%), Gaps = 19/434 (4%) Query 51 RAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDV 110 ++ A+Y + +LAG +RR YG + T+ I G V ++D A K V+ V Sbjct 20 QSILMASYGLRFLAGCQRR-------YGNMFTLRIPLSGKVVYLADPADIKTVYAGDPHV 72 Query 111 LLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHT 170 GE + G S+FV +E EH +R+LL P H A+ R + A + Sbjct 73 FHSGEAHWFFRGLLGDSSLFVLDEDEHHHQRRLLMPAFHRDAVARQATQMAQIAAANIAE 132 Query 171 WPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALR 230 WPV F + + L+VI++ + G DP + L + RLL + E A+ Sbjct 133 WPVGESFPVAPRTTDITLEVILRTVIGASDPVRLAALRKVVPRLLYMKPWET----PAIT 188 Query 231 RLGALRVWP--ARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSD 288 G R WP A R E D ++ A IA+RRADP L ER DVL++LV A + G +SD Sbjct 189 NPGLRRYWPWTAVGRRMAETDALLYAEIAERRADPNLTERTDVLAMLVRATDDDGRTMSD 248 Query 289 SEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVG------GGEAFTTAV 342 E+RD L+T + AGHETTAT L+W + L HPDAL + A G+ + AV Sbjct 249 QELRDHLLTSIAAGHETTATALSWVLERLTRHPDALLKAAQAAEASAAGDPAGDEYLDAV 308 Query 343 INETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERF 402 + ETLR+RP + RV + + +GGY++ G + I ++ S VY P F P+R Sbjct 309 VKETLRIRPVIFSSGRVLKESVEVGGYQLPVGIMVDPAIGLVHASGAVYPDPARFDPDRM 368 Query 403 LGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIML 462 +GT W+PFGGG +RCLGA F+M E+ VL +LR E E+ + + Sbjct 369 VGTTLSPTTWLPFGGGNRRCLGATFAMVEIRVVLREILRRVELNTTTAPDEKQQAKHVTF 428 Query 463 VPRRGTRVRFRPAR 476 VP RG + R R Sbjct 429 VPHRGGSISVRAIR 442 >gi|289747903|ref|ZP_06507281.1| cytochrome P450 138 [Mycobacterium tuberculosis 02_1987] gi|289688431|gb|EFD55919.1| cytochrome P450 138 [Mycobacterium tuberculosis 02_1987] Length=441 Score = 238 bits (606), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 156/443 (36%), Positives = 228/443 (52%), Gaps = 16/443 (3%) Query 34 APDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAI 93 AP + PP + P+ F+ +A++ R + R +RRYG T IL G V + Sbjct 10 APPVVRLPPAVRGPKLFQG-------LAFVVSRRRLLGRFVRRYGKAFTANILMYGRVVV 62 Query 94 VSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAAL 153 V+D LA++VFT+ + L G + ++GSGS+F + +H RRR+LL PP HG ++ Sbjct 63 VADPQLARQVFTSSPEEL--GNIQPNLSRMFGSGSVFALDGDDHRRRRRLLAPPFHGKSM 120 Query 154 DRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE--EVRRLGRPF 211 Y IIE T WP + FA L + L+ I++ IFG E E+RRL P+ Sbjct 121 KNYETIIEEETLRETANWPQGQAFATLPSMMHITLNAILRAIFGAGGSELDELRRLIPPW 180 Query 212 ERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDV 271 + LG S + R G L W A + D V+ LI RADP +R DV Sbjct 181 ---VTLG-SRLAALPRPKRDYGRLSPWGRLAEWRRQYDTVIDKLIEAERADPNFADRTDV 236 Query 272 LSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEA 331 L+L++ + + G +S +I D+L+TL+ AGHETTA TL WAF+ L HPD L + E Sbjct 237 LALMLRSTYDDGSIMSRKDIGDELLTLLAAGHETTAATLGWAFERLSRHPDVLAALVEEV 296 Query 332 VGGGEAFTTAVINETLRVRPPAPLTARVAAQPL-TIGGYRVEAGTRIVVHIIAINRSAEV 390 GG A I E R R AR P+ +G + + G I+++I I+ +V Sbjct 297 DNGGHELRQAAILEVQRARTVIDFAARRVNPPVYQLGEWVIPRGYSIIINIAQIHGDPDV 356 Query 391 YEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDD 450 + P F P+R++G++P +AW+PFGGG +RC+GA F+ E+ VL +LR Sbjct 357 FPQPDRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLETTTA 416 Query 451 EPERIVRRSIMLVPRRGTRVRFR 473 ER R + P+ G RV R Sbjct 417 AGERSHGRGVAFTPKDGGRVVMR 439 >gi|296167326|ref|ZP_06849728.1| cytochrome P450 138 [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897270|gb|EFG76874.1| cytochrome P450 138 [Mycobacterium parascrofulaceum ATCC BAA-614] Length=441 Score = 236 bits (601), Expect = 8e-60, Method: Compositional matrix adjust. Identities = 148/402 (37%), Positives = 212/402 (53%), Gaps = 9/402 (2%) Query 72 RLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFV 131 RL RR+G + T+ + G V +V D LAK++FT D L G + ++GSGS+F Sbjct 41 RLARRHGDVFTLNLPIYGRVVVVGDPQLAKQIFTTSPDEL--GNIQPNLSRLFGSGSVFA 98 Query 132 QEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVI 191 + +H RRR+LL PP HG ++ +Y IIE T WP PFA L + L+ I Sbjct 99 LDGEDHRRRRRLLAPPFHGKSMKKYEAIIEEETLRETAGWPEGEPFATLPSMMRITLNAI 158 Query 192 VKVIFGVDDPE--EVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEID 249 ++ +FG + E E+RRL P+ + LG S T+ R G W + D Sbjct 159 LRAVFGAEGAELDELRRLIPPW---VTLG-SRMATMPKPQRNYGRFSPWGRLDEWRRQYD 214 Query 250 DVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATT 309 ++ LI RADP ER DVL+L++ + + G +S +I D+L+TL+ AGHETTA+T Sbjct 215 TIIDRLIEIERADPNFDERTDVLALMLRSTYDDGSAMSRKDIGDELLTLLAAGHETTAST 274 Query 310 LAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQP-LTIGG 368 LAWAF+ L HPD L + EA G+ A I E R R AR P +G Sbjct 275 LAWAFERLTRHPDVLAALVEEADNDGQELRQATILEVQRARTVIDFAARRVYPPRYQLGE 334 Query 369 YRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFS 428 + + G I+V I I+ + V+ P F P+R++GT+P +AW+PFGGG +RC+GA F+ Sbjct 335 WVIPRGESILVSIAQIHENPAVFSSPERFDPQRYVGTKPSAFAWIPFGGGTRRCVGAAFA 394 Query 429 MRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRV 470 E+ VL +LR E+ R + PR G RV Sbjct 395 NMEMDVVLRTVLRHFTIETTTASGEKWHGRGVAYTPRDGGRV 436 >gi|169977295|emb|CAQ18836.1| putative cytochrome P450 [Chondromyces crocatus] Length=458 Score = 235 bits (600), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 137/418 (33%), Positives = 219/418 (53%), Gaps = 13/418 (3%) Query 72 RLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFV 131 R +++G T+ + GD ++ + VFTA DV+ GE G S+ V Sbjct 30 RWSQQHGDTFTVHMTGSGDFVFITSPEDIRRVFTASIDVIYAGESNSLVRPFVGDSSVVV 89 Query 132 QEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVI 191 + H+R R+ L PP + Y I+ + A++ WPV RPF +L+ + ++++ Sbjct 90 LDGEAHIRSRRQLLPPFQNERMQTYATIMRDVADASLDRWPVGRPFPLLSKMTEIAMELM 149 Query 192 VKVIFGVDDPEEVRRLGRPFERLLNLGVSE-QLTVRYALRRLGALRVWPARARANTEIDD 250 ++ IFG++DP E+ F +L+ S ++ +A L L + ++ ++DD Sbjct 150 LRNIFGLEDPREIATFLERFTSVLDEATSPMRVMASFAGLDLYKLLPFLHVSKLKRQLDD 209 Query 251 VVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTL 310 + LIA+RRA PR R DVL+L++ ++ E G+ ++D E+RD L+TL+ AG+ET+A + Sbjct 210 SIYELIARRRAAPRDPTRQDVLTLILESKHEDGQAMTDRELRDALVTLIAAGYETSAIGM 269 Query 311 AWAFDLLLHHPDALRRVRAEA--VGGGEA----------FTTAVINETLRVRPPAPLTAR 358 +A + LL P AL +V E V G E + A I E+LR+RP PL +R Sbjct 270 TFAVERLLAEPWALAKVHEELDRVLGQETIVAEHLPALEYLDAAIKESLRLRPLVPLISR 329 Query 359 VAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGG 418 P + + + A T ++ ++ + ++Y P F P RFLGT+P YAW+PFGGG Sbjct 330 RTKAPFELSRHTLPAETMLIPALVLTHLREDLYPDPERFDPARFLGTKPDPYAWLPFGGG 389 Query 419 VKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 +RCLG F+M E+ VL +LR + P R+V R IML P G V + R Sbjct 390 ARRCLGMAFAMYEMRMVLATVLRRASLELASNRPVRMVNRHIMLAPSDGAPVVLKARR 447 >gi|289760236|ref|ZP_06519614.1| cytochrome P450 138 [Mycobacterium tuberculosis T85] gi|294994606|ref|ZP_06800297.1| cytochrome P450 138 cyp138 [Mycobacterium tuberculosis 210] gi|289715800|gb|EFD79812.1| cytochrome P450 138 [Mycobacterium tuberculosis T85] gi|326905894|gb|EGE52827.1| cytochrome P450 138 cyp138 [Mycobacterium tuberculosis W-148] gi|339293201|gb|AEJ45312.1| cytochrome P450 138 cyp138 [Mycobacterium tuberculosis CCDC5079] gi|339296848|gb|AEJ48958.1| cytochrome P450 138 cyp138 [Mycobacterium tuberculosis CCDC5180] Length=441 Score = 234 bits (596), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 155/443 (35%), Positives = 227/443 (52%), Gaps = 16/443 (3%) Query 34 APDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAI 93 AP + PP + P+ F+ +A++ R + R +RRYG T IL G V + Sbjct 10 APPVVRLPPAVRGPKLFQG-------LAFVVSRRRLLGRFVRRYGKAFTANILMYGRVVV 62 Query 94 VSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAAL 153 V+D LA++VFT+ + L G + ++GSGS+F + +H RRR+LL P HG ++ Sbjct 63 VADPQLARQVFTSSPEEL--GNIQPNLSRMFGSGSVFALDGDDHRRRRRLLAPFFHGKSM 120 Query 154 DRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE--EVRRLGRPF 211 Y IIE T WP + FA L + L+ I++ IFG E E+RRL P+ Sbjct 121 KNYETIIEEETLRETANWPQGQAFATLPSMMHITLNAILRAIFGAGGSELDELRRLIPPW 180 Query 212 ERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDV 271 + LG S + R G L W A + D V+ LI RADP +R DV Sbjct 181 ---VTLG-SRLAALPKPKRDYGRLSPWGRLAEWRRQYDTVIDKLIEAERADPNFADRTDV 236 Query 272 LSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEA 331 L+L++ + + G +S +I D+L+TL+ AGHETTA TL WAF+ L HPD L + E Sbjct 237 LALMLRSTYDDGSIMSRKDIGDELLTLLAAGHETTAATLGWAFERLSRHPDVLAALVEEV 296 Query 332 VGGGEAFTTAVINETLRVRPPAPLTARVAAQPL-TIGGYRVEAGTRIVVHIIAINRSAEV 390 GG A I E R R AR P+ +G + + G I+++I I+ +V Sbjct 297 DNGGHELRQAAILEVQRARTVIDFAARRVNPPVYQLGEWVIPRGYSIIINIAQIHGDPDV 356 Query 391 YEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDD 450 + P F P+R++G++P +AW+PFGGG +RC+GA F+ E+ VL +LR Sbjct 357 FPQPDRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLETTTA 416 Query 451 EPERIVRRSIMLVPRRGTRVRFR 473 ER R + P+ G RV R Sbjct 417 AGERSHGRGVAFTPKDGGRVVMR 439 >gi|183984401|ref|YP_001852692.1| cytochrome P450 138B1 Cyp138B1 [Mycobacterium marinum M] gi|183177727|gb|ACC42837.1| cytochrome P450 138B1 Cyp138B1 [Mycobacterium marinum M] Length=456 Score = 232 bits (592), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 148/448 (34%), Positives = 221/448 (50%), Gaps = 17/448 (3%) Query 32 EHAPDALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDV 91 E D + PPG A + + Y+ R RL RYG ++ + G Sbjct 3 EATTDPIQLPPGPNASK-------LTQTLVYVFAKARARTRLTNRYGSGYSLNLPKYGPT 55 Query 92 AIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGA 151 ++SD A+ KE+FT+ D++ +G + G GS+ EH +RRKL+ PP G Sbjct 56 LVISDPAMLKELFTSGNDLVTRPTTLG---KLLGPGSILSMIGVEHRQRRKLMVPPFSGR 112 Query 152 ALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDP--EEVRRLGR 209 +D YV I+E TWP + F L ++ ++++ I G EE++ LG Sbjct 113 RIDAYVKIVEEEFLREAQTWPEETEFESLQALVNITGSIVLRTILGAHGAIFEELQYLG- 171 Query 210 PFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERH 269 R + L + R LG W A + D+++ LIA+ RADP R Sbjct 172 --PRTIVLAARMIALPEWLRRDLGPWSPWGKIQAARSRFDELIAQLIAEARADPNFETRT 229 Query 270 DVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRA 329 D+L++++ AR + G ++D+ I D+++T+++AGHETTATTLAWA + L P + ++ Sbjct 230 DMLAMMLQARYDDGSPITDAHISDEMLTMIVAGHETTATTLAWAVERLRRSPSFVAQLVD 289 Query 330 EAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAE 389 E GG A A + E R RP AR L +G + + G IV + A ++ Sbjct 290 EIDNGGTALMQATVWEVQRTRPVLDFIARRVETQLRLGPWVLPKGHMIVGDVWAAQHASS 349 Query 390 VYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVD 449 ++ P F P RF P++YAW+PFGGG+ RC+GA F+ E+ TVL LLR+ E D Sbjct 350 SFKDPERFDPTRFADGPPESYAWIPFGGGIHRCIGAAFANMEMTTVLRTLLRKFELVPTD 409 Query 450 DEPERIVRRSIMLVPRRGTR--VRFRPA 475 E I R I P G R VR RPA Sbjct 410 APAEPIRSRGITNAPGHGGRIVVRSRPA 437 >gi|186684527|ref|YP_001867723.1| cytochrome P450 [Nostoc punctiforme PCC 73102] gi|186466979|gb|ACC82780.1| cytochrome P450 [Nostoc punctiforme PCC 73102] Length=464 Score = 232 bits (591), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 137/413 (34%), Positives = 217/413 (53%), Gaps = 19/413 (4%) Query 75 RRYGPIMTMPI-LSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQE 133 +RYG I T+ + + +S+ +++FT L GE G A + G S+ + Sbjct 34 KRYGDIFTLKLGQNFAHQVFISNPQAIQQIFTTDPKQLDSGESAGIKAPLLGQQSLLALD 93 Query 134 EPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVK 193 H R+RKLLTPP HG + Y +I T W V FA+L +++ VI+K Sbjct 94 GKPHQRQRKLLTPPFHGERMLAYGELIREITEQVSSQWQVGETFAVLPSMQAISFQVILK 153 Query 194 VIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYAL----RRLGALRVWPARARANTEID 249 +FG++D ++L ++LN + TV + LGA W R +ID Sbjct 154 AVFGLEDGPRYKKLNELLIKILNPKIPLLRTVLLIFPSMRQDLGAWSPWGKYLRLRQQID 213 Query 250 DVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATT 309 ++ A I +R+A P L D+LSL+++AR E+GE ++D E+RD+L+TL++AGHETTAT+ Sbjct 214 QLIYAQIQERKAQPNLSGT-DILSLMMAARDEAGEPMTDLELRDELMTLLVAGHETTATS 272 Query 310 LAWAFDLLLHHPDALRRVRAEAVGGGEA----------FTTAVINETLRVRPPAPLTA-- 357 L+WA + H P ++ E GE + AV +ETLR+ P A ++A Sbjct 273 LSWALYWIHHRPQVREKLLQELDNLGEKPDPNAIFRLPYLNAVCSETLRLYPVA-MSALN 331 Query 358 RVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGG 417 R+ PL IG Y E GT ++ I + ++Y +F+PERFL + Y ++PFGG Sbjct 332 RLVKSPLQIGEYNFEPGTILIPSIYLTHHREDLYPESKQFKPERFLERQFSPYEYLPFGG 391 Query 418 GVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRV 470 G +RC+G F++ E+ VL +L + D +P R VR+ ++ P G ++ Sbjct 392 GNRRCIGMAFALFEMKLVLATVLSRWQMELADSKPVRPVRKGLLFSPAGGVQM 444 >gi|169628518|ref|YP_001702167.1| putative cytochrome P450 [Mycobacterium abscessus ATCC 19977] gi|169240485|emb|CAM61513.1| Putative cytochrome P450 [Mycobacterium abscessus] Length=446 Score = 231 bits (590), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 146/420 (35%), Positives = 211/420 (51%), Gaps = 10/420 (2%) Query 57 AYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEG 116 A +A++A RL ++YG + T+ I G +V+D L +EVFT T++L G Sbjct 32 AQGIAFVASRRWTTSRLAKKYGKVYTINIPKFGYTVVVADPDLTREVFTTSTEIL--GNI 89 Query 117 VGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRP 176 + G GS+F E EH RRKLL P HG A+ +Y IIE T TWP + Sbjct 90 QPNLSQQLGPGSVFALERNEHRHRRKLLAPKFHGKAMVQYEQIIEEETLRECATWPEGQQ 149 Query 177 FAMLTVARSLMLDVIVKVIFGVDDPE--EVRRLGRPFERLLNLGVSEQLTVRYALRRLGA 234 F + + L+ I++ +FG D E +RRL P+ L +L + R G Sbjct 150 FETMEPMMRITLNAILRAVFGADGAELDVLRRLIPPWVVLASLTTR----IPQPKRNYGR 205 Query 235 LRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDD 294 W D V+ +LI + A P +R D+L+LL+ + + G +S S++ D+ Sbjct 206 FSPWGRLKTYRAHYDAVIGSLIEKALAAPDFEDRTDILALLLRSTYDDGTTMSRSDVSDE 265 Query 295 LITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAP 354 L+TL+ AGHETTATTLAWAF+ + HP+ L R+ EA G + A I E R RP Sbjct 266 LLTLLAAGHETTATTLAWAFERITRHPEVLSRLAEEAQGDSNEYRQATILEVQRSRPVID 325 Query 355 LTAR-VAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWV 413 R V A + IG YR+ G +VV I ++ + P F PERF+G +P +WV Sbjct 326 FAGRHVLAPHVDIGPYRIPQGHSVVVSINLMHDDPVAFPCPERFDPERFMGAKPGN-SWV 384 Query 414 PFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFR 473 P+GGG +RC+GA F+ E+ VL +LR E+ R + P+ RV R Sbjct 385 PYGGGTRRCVGAAFANMEMDIVLRTVLRHFTIETTTAPDEKWHSRGVASCPKNNGRVTVR 444 >gi|333920661|ref|YP_004494242.1| cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1] gi|333482882|gb|AEF41442.1| Cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1] Length=439 Score = 231 bits (590), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 148/403 (37%), Positives = 210/403 (53%), Gaps = 8/403 (1%) Query 73 LIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQ 132 L +RYG + ++ + + ++ + VF P D+ GEG I G S+ Sbjct 35 LRKRYGDVFSLSVYPQRHLVQLAHPDDIRAVFGGPPDLFHAGEGNMILTPIVGEQSVLTT 94 Query 133 EEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIV 192 +E +H R R LL PP HG AL Y ++ WPV RPFA + ++L L++I+ Sbjct 95 DEDQHRRLRGLLMPPFHGQALRGYRNMVAALAIDDASRWPVGRPFATHSRMQALTLEIIM 154 Query 193 KVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYA-LRRLGALRVWPARARANTEIDDV 251 +V+FGV + + L RL++L + V LRR G W EID + Sbjct 155 RVVFGVAEGPRLDALRDLLGRLVSLNLLSLFGVHDPRLRRFGP---WRRTVGMQREIDAL 211 Query 252 VMALIAQRRADPRLGERHDVLSLLVSARGESG----EQLSDSEIRDDLITLVLAGHETTA 307 + + I++RR L +R DVLS L++ + + L+D+E+RD LITL+LAGHETTA Sbjct 212 LGSEISERRRATDLADRPDVLSQLIAGSSAAAGTASDGLTDAELRDQLITLLLAGHETTA 271 Query 308 TTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIG 367 T LAWAF L P+ R R A+ G + + A+ E LR+RP AR + + I Sbjct 272 TALAWAFHELARDPERQRLGREAALNGDDKYLEAIFKEALRLRPVIYEVARTLTEDIEIR 331 Query 368 GYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANF 427 G+R+ AG ++ I + E +E P FRPERFL P W+PFGGGV+RCLGA F Sbjct 332 GFRIPAGYTVMPMIGVVQSDPEHHEDPELFRPERFLNGSPAPNTWIPFGGGVRRCLGAGF 391 Query 428 SMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRV 470 + E VL +L F PER V R+I L PRRG R+ Sbjct 392 AQMEGTEVLRAVLSRYTFMPDRVAPERAVPRNITLTPRRGGRI 434 >gi|218437822|ref|YP_002376151.1| cytochrome P450 [Cyanothece sp. PCC 7424] gi|218170550|gb|ACK69283.1| cytochrome P450 [Cyanothece sp. PCC 7424] Length=453 Score = 231 bits (588), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 141/445 (32%), Positives = 226/445 (51%), Gaps = 25/445 (5%) Query 42 PGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALAK 101 P + AP + A + YL RM G I + + I+ D + Sbjct 16 PKITAPVWLQTVEALFQPLEYLEKQRSRM-------GDIYWGESFAFPHLVIIGDPKGIE 68 Query 102 EVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIE 161 +VFTA + G I G S+ + + H ++RKLL PP HG + Y I Sbjct 69 QVFTADPNCFEIGNSNKIVHPIVGGYSLILLDGQSHQQQRKLLMPPFHGERMRNYGQTIY 128 Query 162 NSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNL--GV 219 N T+ M WP ++PF M + + L VI++ +FGV E++ RL L + V Sbjct 129 NVTQQVMEKWPKNQPFLMRQSTQEITLRVIIETVFGVHQGEKLERLQHLLNEFLEIFNKV 188 Query 220 SEQLTVRYAL--RRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVS 277 + + Y + + LGA W R EID+++ I +RR D+LSL++S Sbjct 189 WGAMFLFYPILQKDLGAWSPWGKYLRLRQEIDEILFTEIKERRHQ---LPTEDILSLMIS 245 Query 278 ARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPD-------ALRRVRAE 330 A+ E+G+ +SD E+RD+L+TL+ AGHETTA+ +AWAF + P+ L+ V E Sbjct 246 AKDENGQSMSDQELRDELMTLLFAGHETTASAIAWAFYWIHRQPEIKQKLLEELKEVDVE 305 Query 331 AVGGGEA---FTTAVINETLRVRPPAPLT-ARVAAQPLTIGGYRVEAGTRIVVHIIAINR 386 G A + +AV ETLR+ P A +R P+ I GY++E G ++ I +++ Sbjct 306 NEGITVAKLPYLSAVCAETLRIYPVAIFAFSRKTKVPMEIMGYQIEPGMTLLPSIYSVHH 365 Query 387 SAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFT 446 ++Y + +FRPERFL + Y ++PFGGG +RCLG F++ E+ VL +L++ + T Sbjct 366 REDIYPNAKQFRPERFLERQFSPYEYLPFGGGNRRCLGYAFALFEMKLVLATILKQTQLT 425 Query 447 AVDDEPERIVRRSIMLVPRRGTRVR 471 ++ + + +RRS+ P G ++R Sbjct 426 LLEPKEVKPMRRSVTFTPSTGIKMR 450 >gi|118467999|ref|YP_885605.1| cytochrome P450 monooxygenase [Mycobacterium smegmatis str. MC2 155] gi|118169286|gb|ABK70182.1| cytochrome P450 monooxygenase [Mycobacterium smegmatis str. MC2 155] Length=437 Score = 229 bits (584), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 140/405 (35%), Positives = 210/405 (52%), Gaps = 5/405 (1%) Query 75 RRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEE 134 RRYG + T+ I S+G ++D A K VF V GE + + G S+ V +E Sbjct 19 RRYGDVFTLRIASMGTWVYLADPADIKTVFAGDPTVFHAGEANSMLSGLLGETSVLVIDE 78 Query 135 PEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKV 194 H RR+L+ P A+ R ++ + +WPV PF + + L+VI++ Sbjct 79 DVHRDRRRLMLAPFARDAVARQTGVMAEVAATNIASWPVGTPFPVAPKMAEIALEVILRT 138 Query 195 IFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMA 254 + G +P + L +LL +G + L + A L R W R E D ++ A Sbjct 139 VIGATEPARLAALRHVMPQLLGIGPWQSLAI--ASPGLQRRRPWRTLQRNLAEADRLLYA 196 Query 255 LIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAF 314 IA RA P L R D L++LV A + G ++D E+RD L+TL++AGHETTAT L+W Sbjct 197 EIAACRAGPDLASRPDALAMLVRAANDEGRTMTDRELRDQLMTLLVAGHETTATGLSWTL 256 Query 315 DLLLHHPDALRRVRAEA---VGGGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRV 371 + L+ HP L + A A G GEA+ AV+ E+LR+RP RV +P+ +GGY + Sbjct 257 ERLIRHPAVLDKAVAAARTTDGSGEAYLDAVVRESLRIRPVVFEAGRVLTEPVELGGYLL 316 Query 372 EAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRE 431 AGT + I ++ SA+VY P F P+R L + W+PFGGG +RCLGA F++ E Sbjct 317 PAGTLVAPSIGLVHASADVYPDPDRFEPDRMLASTQAPSTWLPFGGGNRRCLGATFALVE 376 Query 432 LITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFRPAR 476 + VL +L + A E+ + + ++P RG R+ R R Sbjct 377 MRVVLREILHRVDLFATTARGEKQRLKHVTMIPHRGGRICVRALR 421 >gi|183982980|ref|YP_001851271.1| cytochrome P450 135B6 Cyp135B6 [Mycobacterium marinum M] gi|183176306|gb|ACC41416.1| cytochrome P450 135B6 Cyp135B6 [Mycobacterium marinum M] Length=473 Score = 228 bits (582), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 147/442 (34%), Positives = 224/442 (51%), Gaps = 22/442 (4%) Query 41 PPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVSDSALA 100 PPG P R +AA +LA RR YG + T+ I +G ++D Sbjct 10 PPGPPLSRSLQAALMLLRGPQFLAACRRR-------YGDVFTLRIARMGTQVYLADPRDI 62 Query 101 KEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPII 160 K VFT T + G+ + + G S+ V +E H RR+ + P H A+ R ++ Sbjct 63 KTVFTGDTHIFHAGDANALLSGLIGDSSLMVLDEEAHRCRRRTMLAPFHRDAVARQAGLM 122 Query 161 ENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVS 220 + WP R F + + L+VI++ + G DP + L RLL++G Sbjct 123 AEIAADNVAGWPAGRTFPVTVRMSEITLEVILRTVIGATDPARLAALRTAVPRLLSMGPW 182 Query 221 EQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARG 280 L + A +L + R W + ++D+++ A I RR D LG+R DVL++L+ G Sbjct 183 GTLAL--ANPKLLSRRPWRGLRKRIADVDNLLYAEITDRRNDAELGKRADVLAMLIRTEG 240 Query 281 ESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGG------ 334 ++D E+RD L+TL++AG++T+AT LAWA + L HP L R A A Sbjct 241 ND-NAMTDRELRDQLVTLLVAGYDTSATGLAWALERLTRHPTILTRAVAAAHASAAGDAA 299 Query 335 GEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHP 394 G+ + AV+ ETLR+RP A RV A P+ + GY++ AG + I ++ SA +Y P Sbjct 300 GDEYLDAVVKETLRIRPLAFAVGRVLAAPVEVAGYQLPAGAWALPGIGLVHASAALYPDP 359 Query 395 HEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEF---TAVDDE 451 F P+R +G P W+PFGGG +RCLGA F++ E+ VL +LR E TA D+ Sbjct 360 DRFDPDRMIGVSPGPTTWLPFGGGARRCLGATFALVEMRVVLREVLRRAELITTTAADET 419 Query 452 PERIVRRSIMLVPRRGTRVRFR 473 P+ + + L+P RG R+ R Sbjct 420 PK---LKYVTLIPSRGARISVR 438 >gi|254777502|ref|ZP_05219018.1| cytochrome P450 monooxygenase [Mycobacterium avium subsp. avium ATCC 25291] Length=438 Score = 228 bits (581), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 157/431 (37%), Positives = 221/431 (52%), Gaps = 18/431 (4%) Query 45 PAPRGFRAAFAAAYAVAYLAGGERR--MLRLIRRYGPIMTMPILSLGDVAIVSDSALAKE 102 PA RG + +AV+ RR M RL RRYG + T+ + G V +VSD LAK+ Sbjct 16 PAVRGPKLLQGIGFAVS------RRTMMRRLSRRYGNVFTLRLPMWGPVVMVSDPQLAKQ 69 Query 103 VFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIEN 162 +FT D L G + ++GSGS+F E +H RRR+LL PP HG ++ Y IIE Sbjct 70 IFTTSPDEL--GNIQPNLSRLFGSGSVFGLEGDDHRRRRRLLAPPFHGKSMKNYESIIEE 127 Query 163 STRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE--EVRRLGRPFERLLNLGVS 220 T WP F L + L+ I++ +FG + E E+RRL P+ L + + Sbjct 128 ETLRETAGWPEGESFPTLPPMMRITLNAILRAVFGAEGAELDELRRLIPPWVTLGSRLAA 187 Query 221 EQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARG 280 RY R G W R + D V+ LIA +ADP ER DVL+LL+ + Sbjct 188 LPKPQRYP--RFGP---WGQLDRWRRQYDGVIERLIAAEQADPNFAERTDVLALLLRSTY 242 Query 281 ESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTT 340 + G +S EI D+L+TL+ AGHETTA+TLAWAF+ + HP+ L R+ EA GG Sbjct 243 DDGAAMSHKEIGDELLTLLAAGHETTASTLAWAFERISRHPELLARLVEEADNGGNELRQ 302 Query 341 AVINETLRVRPPAPLTAR-VAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRP 399 A I E R R R V +G + + G I+V I I+ + +V+ P F P Sbjct 303 AAILEVQRARTVIDFAGRHVYPDVYRLGEWVIPRGYSIIVGIAQIHDNPDVFPDPRRFDP 362 Query 400 ERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRS 459 +RF+ +P +W+PFGGG +RC+GA F+ E+ VL +LR D E R Sbjct 363 QRFIDNKPSALSWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTIETTDAPDEPWHCRG 422 Query 460 IMLVPRRGTRV 470 + P+ G R+ Sbjct 423 VAFTPKHGGRI 433 >gi|118465972|ref|YP_884277.1| cytochrome P450 monooxygenase [Mycobacterium avium 104] gi|118167259|gb|ABK68156.1| cytochrome P450 monooxygenase [Mycobacterium avium 104] Length=438 Score = 228 bits (580), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 157/431 (37%), Positives = 221/431 (52%), Gaps = 18/431 (4%) Query 45 PAPRGFRAAFAAAYAVAYLAGGERR--MLRLIRRYGPIMTMPILSLGDVAIVSDSALAKE 102 PA RG + +AV+ RR M RL RRYG + T+ + G V +VSD LAK+ Sbjct 16 PAVRGPKLLQGIGFAVS------RRTMMRRLSRRYGNVFTLRLPMWGPVVMVSDPQLAKQ 69 Query 103 VFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDRYVPIIEN 162 +FT D L G + ++GSGS+F E +H RRR+LL PP HG ++ Y IIE Sbjct 70 IFTTSPDEL--GNIQPNLSRLFGSGSVFGLEGDDHRRRRRLLAPPFHGKSMKNYESIIEE 127 Query 163 STRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPE--EVRRLGRPFERLLNLGVS 220 T WP F L + L+ I++ +FG + E E+RRL P+ L + + Sbjct 128 ETLRETAGWPEGESFPTLPPMMRITLNAILRAVFGAEGAELDELRRLIPPWVTLGSRLAA 187 Query 221 EQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARG 280 RY R G W R + D V+ LIA +ADP ER DVL+LL+ + Sbjct 188 LPKPQRYP--RFGP---WGQLDRWRRQYDGVIERLIAAEQADPNFAERTDVLALLLRSTY 242 Query 281 ESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTT 340 + G +S EI D+L+TL+ AGHETTA+TLAWAF+ + HP+ L R+ EA GG Sbjct 243 DDGAAMSHKEIGDELLTLLAAGHETTASTLAWAFERISRHPELLARLVEEADNGGNELRQ 302 Query 341 AVINETLRVRPPAPLTAR-VAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRP 399 A I E R R R V +G + + G I+V I I+ + +V+ P F P Sbjct 303 AAILEVQRARTVIDFAGRHVYPDVYRLGEWVIPRGYSIIVGIAQIHDNPDVFPDPRRFDP 362 Query 400 ERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRS 459 +RF+ +P +W+PFGGG +RC+GA F+ E+ VL +LR D E R Sbjct 363 QRFIDNKPSALSWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTIETTDAPDEPWHCRG 422 Query 460 IMLVPRRGTRV 470 + P+ G R+ Sbjct 423 VAFTPKHGGRI 433 >gi|336459910|gb|EGO38822.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis S397] Length=403 Score = 228 bits (580), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 147/404 (37%), Positives = 209/404 (52%), Gaps = 10/404 (2%) Query 70 MLRLIRRYGPIMTMPILSLGDVAIVSDSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSM 129 M RL RRYG + T+ + G V +VSD LAK++FT D L G + ++GSGS+ Sbjct 2 MRRLSRRYGNVFTLRLPMWGPVVMVSDPQLAKQIFTTTPDEL--GNIQPNLSRLFGSGSV 59 Query 130 FVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLD 189 F E +H RRR+LL PP HG ++ Y IIE T WP F L + L+ Sbjct 60 FGLEGDDHRRRRRLLAPPFHGKSMKNYESIIEEETLRETAGWPEGESFPTLPPMMRITLN 119 Query 190 VIVKVIFGVDDPE--EVRRLGRPFERLLNLGVSEQLTVRYALRRLGALRVWPARARANTE 247 I++ +FG + E E+RRL P+ + +S +L +R W R Sbjct 120 AILRAVFGAEGAELDELRRLIPPW-----VTLSSRLAALPKPQRYPRFGPWGQLDRWRRH 174 Query 248 IDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHETTA 307 D V+ LIA +ADP ER DVL+LL+ + + G +S EI D+L+TL+ AGHETTA Sbjct 175 YDGVIERLIAAEQADPNFAERTDVLALLLRSTYDDGAAMSHKEIGDELLTLLAAGHETTA 234 Query 308 TTLAWAFDLLLHHPDALRRVRAEAVGGGEAFTTAVINETLRVRPPAPLTAR-VAAQPLTI 366 +TLAWAF+ + HP+ L R+ EA GG A I E R R R V + Sbjct 235 STLAWAFERISRHPELLARLVEEADNGGNELRQATILEVQRARTVIDFAGRHVYPDVYRL 294 Query 367 GGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGAN 426 G + + G I+V I I+ + +V+ P F P+RF+ +P +W+PFGGG +RC+GA Sbjct 295 GEWVIPRGYSIIVGIAQIHDNPDVFPDPRRFDPQRFIDNKPSALSWIPFGGGTRRCVGAA 354 Query 427 FSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRV 470 F+ E+ VL +LR D E R + P+ G R+ Sbjct 355 FANMEMDVVLRTVLRHFTIETTDAPDEPWHCRGVAFTPKHGGRI 398 >gi|340625595|ref|YP_004744047.1| putative cytochrome P450 135B1 CYP135B1 [Mycobacterium canettii CIPT 140010059] gi|340003785|emb|CCC42911.1| putative cytochrome P450 135B1 CYP135B1 [Mycobacterium canettii CIPT 140010059] Length=472 Score = 228 bits (580), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 156/447 (35%), Positives = 229/447 (52%), Gaps = 15/447 (3%) Query 36 DALGGPPGLPAPRGFRAAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGDVAIVS 95 ++G PPG PR + AV L G R + RRYG + T+ + G + +S Sbjct 5 SSMGLPPG---PR----LSGSVQAVLMLRHGLRFLTACQRRYGSVFTLHVAGFGHMVYLS 57 Query 96 DSALAKEVFTAPTDVLLGGEGVGPAAAIYGSGSMFVQEEPEHLRRRKLLTPPLHGAALDR 155 D A K VF V GE A + G S+ + ++ H RR+L+ PP H A+ R Sbjct 58 DPAAIKTVFAGNPRVFHAGEANSMLAGLLGDSSLLLIDDDVHRDRRRLMLPPFHRDAVAR 117 Query 156 YVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLDVIVKVIFGVDDPEEVRRLGRPFERLL 215 ++ A + WP+ + FA+ + L+VI++ + G DP + L + RLL Sbjct 118 QAGLMAEIAAANIAGWPMAKQFAVAPKMSEITLEVILRTVIGASDPARLAALRKVMPRLL 177 Query 216 NLGVSEQLTVRYALRRLGALRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLL 275 N+G T+ A L R+W R E D ++ A IA RRADP L R D L++L Sbjct 178 NVG--PWATLALANPSLLNNRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAML 235 Query 276 VSARGESGEQLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVG-- 333 V A E G +++ E+RD LITL++AGH+TTAT L+WA + L HP L + A Sbjct 236 VRAADEDGRTMTERELRDQLITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQAADASA 295 Query 334 ----GGEAFTTAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAE 389 G+ + AV ETLR+RP RV + + + GYR+ AG +V I ++ S++ Sbjct 296 AGDPAGDEYLDAVAKETLRIRPVVYDVGRVLTEAVEVAGYRLPAGVMVVPAIGLVHASSQ 355 Query 390 VYEHPHEFRPERFLGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVD 449 +Y P F P+R +G W+PFGGG +RCLGA F+M E+ VL +LR E + Sbjct 356 LYPDPERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVELSTTT 415 Query 450 DEPERIVRRSIMLVPRRGTRVRFRPAR 476 ER + +++VP RG R+R R R Sbjct 416 TSGERPKLKHVIMVPHRGARIRVRATR 442 >gi|307153475|ref|YP_003888859.1| cytochrome P450 [Cyanothece sp. PCC 7822] gi|306983703|gb|ADN15584.1| cytochrome P450 [Cyanothece sp. PCC 7822] Length=457 Score = 227 bits (579), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 138/419 (33%), Positives = 218/419 (53%), Gaps = 19/419 (4%) Query 72 RLIRRYGPIMTMPILSLGDVAI-VSDSALAKEVFTA-PTDVLLGGEGVGPAAAIYGSGSM 129 R ++YG I P SL + +SD ++V TA P +G + + G S+ Sbjct 38 RNYQKYGDIFYTPKSSLFPAFVALSDPKAVEKVLTANPRLFEVGKQSSLAVRVLLGDNSL 97 Query 130 FVQEEPEHLRRRKLLTPPLHGAALDRYVPIIENSTRAAMHTWPVDRPFAMLTVARSLMLD 189 + + EH +RRKLL PP HG + Y I + T+ M W + F++ + + L Sbjct 98 VLLDGIEHQKRRKLLMPPFHGERMKSYGQTIVDVTKEVMAQWQEGKSFSIRDYTQQISLR 157 Query 190 VIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQ----LTVRYALRRLGALRVWPARARAN 245 VI++ +FG+D+ E RL + LN+ S L + GA W Sbjct 158 VILRTVFGLDEGERYARLEKILTAWLNIFNSPFNAFFLFFPVLQKDFGAWTPWGQFVEQK 217 Query 246 TEIDDVVMALIAQRRADP-RLGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVLAGHE 304 I +++ + I +RR +P LGE D+LSLL+S E G+ +SD+EI+D+L+T++ AGHE Sbjct 218 RLIHEILQSEIERRRHNPDSLGE--DILSLLLSVEDEEGQPMSDTEIKDELMTMLFAGHE 275 Query 305 TTATTLAWAFDLLLHHPDALRRVRAEAVGGGEA----------FTTAVINETLRVRPPAP 354 TTA TLAWAF + + P+ +++ AE E + AV++ETLR+ P P Sbjct 276 TTANTLAWAFYWIHYRPEIYQKLLAELNSLDENADFNAINKLPYLNAVVSETLRLYPVVP 335 Query 355 LTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTRPQTYAWVP 414 +R +P I GY+ EAGT ++ I I++ ++Y P +F+PERFL + Y ++P Sbjct 336 FLSRQLKEPFEIMGYQFEAGTALLPCIYLIHQREDIYPQPKQFKPERFLEKQFSPYEYLP 395 Query 415 FGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVPRRGTRVRFR 473 FGGG +RCLG F++ E+ VL +L + P + +RR I P G ++R + Sbjct 396 FGGGHRRCLGYAFALFEMKLVLATVLSQVHLELPFQRPPKAIRRGITFAPSGGLKMRLK 454 Lambda K H 0.324 0.139 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1012998292362 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40