BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3699

Length=233
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15843318|ref|NP_338355.1|  hypothetical protein MT3802 [Mycoba...   471    3e-131
gi|15610835|ref|NP_218216.1|  hypothetical protein Rv3699 [Mycoba...   470    6e-131
gi|289441133|ref|ZP_06430877.1|  conserved hypothetical protein [...   469    2e-130
gi|253800744|ref|YP_003033745.1|  hypothetical protein TBMG_03742...   468    3e-130
gi|340628672|ref|YP_004747124.1|  hypothetical protein MCAN_37201...   466    1e-129
gi|183985179|ref|YP_001853470.1|  hypothetical protein MMAR_5210 ...   371    4e-101
gi|240173387|ref|ZP_04752045.1|  hypothetical protein MkanA1_2900...   363    8e-99 
gi|254821111|ref|ZP_05226112.1|  thiopurine S-methyltransferase (...   358    4e-97 
gi|296166787|ref|ZP_06849207.1|  thiopurine S-methyltransferase f...   335    3e-90 
gi|41406399|ref|NP_959235.1|  hypothetical protein MAP0301 [Mycob...   332    3e-89 
gi|118466516|ref|YP_879689.1|  thiopurine S-methyltransferase (tp...   330    8e-89 
gi|254773409|ref|ZP_05214925.1|  thiopurine S-methyltransferase (...   327    9e-88 
gi|336460875|gb|EGO39760.1|  Thiopurine S-methyltransferase (TPMT...   325    3e-87 
gi|342861937|ref|ZP_08718581.1|  thiopurine S-methyltransferase (...   323    2e-86 
gi|289748214|ref|ZP_06507592.1|  conserved hypothetical protein [...   319    2e-85 
gi|108801840|ref|YP_642037.1|  type 12 methyltransferase [Mycobac...   316    2e-84 
gi|118467923|ref|YP_890454.1|  thiopurine S-methyltransferase (tp...   313    2e-83 
gi|120406418|ref|YP_956247.1|  type 11 methyltransferase [Mycobac...   273    2e-71 
gi|240168945|ref|ZP_04747604.1|  hypothetical protein MkanA1_0651...   271    6e-71 
gi|145221916|ref|YP_001132594.1|  type 11 methyltransferase [Myco...   268    5e-70 
gi|317506538|ref|ZP_07964335.1|  methyltransferase domain-contain...   249    2e-64 
gi|169628058|ref|YP_001701707.1|  hypothetical protein MAB_0961c ...   249    2e-64 
gi|296393423|ref|YP_003658307.1|  type 11 methyltransferase [Segn...   234    7e-60 
gi|111020498|ref|YP_703470.1|  methyltransferase [Rhodococcus jos...   234    8e-60 
gi|226362123|ref|YP_002779901.1|  hypothetical protein ROP_27090 ...   228    7e-58 
gi|183980930|ref|YP_001849221.1|  methyltransferase [Mycobacteriu...   225    5e-57 
gi|240172077|ref|ZP_04750736.1|  hypothetical protein MkanA1_2236...   222    4e-56 
gi|118616465|ref|YP_904797.1|  methyltransferase [Mycobacterium u...   217    9e-55 
gi|169627497|ref|YP_001701146.1|  methyltransferase [Mycobacteriu...   216    3e-54 
gi|342860173|ref|ZP_08716825.1|  hypothetical protein MCOL_14880 ...   213    1e-53 
gi|41406223|ref|NP_959059.1|  hypothetical protein MAP0125c [Myco...   212    3e-53 
gi|340625587|ref|YP_004744039.1|  putative benzoquinone methyltra...   212    3e-53 
gi|336458089|gb|EGO37075.1|  Thiopurine S-methyltransferase (TPMT...   212    4e-53 
gi|254822596|ref|ZP_05227597.1|  hypothetical protein MintA_21884...   212    4e-53 
gi|118465195|ref|YP_879415.1|  thiopurine S-methyltransferase (tp...   212    4e-53 
gi|254773164|ref|ZP_05214680.1|  thiopurine S-methyltransferase (...   211    5e-53 
gi|308231588|ref|ZP_07413001.2|  benzoquinone methyltransferase [...   210    1e-52 
gi|15607700|ref|NP_215074.1|  benzoquinone methyltransferase [Myc...   210    2e-52 
gi|298524048|ref|ZP_07011457.1|  conserved hypothetical protein [...   209    2e-52 
gi|296167043|ref|ZP_06849455.1|  thiopurine S-methyltransferase f...   207    1e-51 
gi|333989194|ref|YP_004521808.1|  methyltransferase [Mycobacteriu...   204    9e-51 
gi|169629918|ref|YP_001703567.1|  hypothetical protein MAB_2834c ...   196    2e-48 
gi|118470628|ref|YP_886876.1|  thiopurine S-methyltransferase (tp...   185    4e-45 
gi|342860008|ref|ZP_08716660.1|  hypothetical protein MCOL_14050 ...   183    2e-44 
gi|254822456|ref|ZP_05227457.1|  hypothetical protein MintA_21156...   181    1e-43 
gi|289571942|ref|ZP_06452169.1|  conserved hypothetical protein [...   173    2e-41 
gi|41406366|ref|NP_959202.1|  hypothetical protein MAP0268c [Myco...   168    7e-40 
gi|118467221|ref|YP_879601.1|  thiopurine S-methyltransferase (tp...   167    1e-39 
gi|254773323|ref|ZP_05214839.1|  thiopurine S-methyltransferase (...   163    2e-38 
gi|169631872|ref|YP_001705521.1|  hypothetical protein MAB_4799c ...   161    7e-38 


>gi|15843318|ref|NP_338355.1| hypothetical protein MT3802 [Mycobacterium tuberculosis CDC1551]
 gi|13883679|gb|AAK48169.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
Length=236

 Score =  471 bits (1213),  Expect = 3e-131, Method: Compositional matrix adjust.
 Identities = 233/233 (100%), Positives = 233/233 (100%), Gaps = 0/233 (0%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL
Sbjct  4    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  63

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST
Sbjct  64   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  123

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY
Sbjct  124  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  183

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG
Sbjct  184  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  236


>gi|15610835|ref|NP_218216.1| hypothetical protein Rv3699 [Mycobacterium tuberculosis H37Rv]
 gi|31794870|ref|NP_857363.1| hypothetical protein Mb3725 [Mycobacterium bovis AF2122/97]
 gi|121639614|ref|YP_979838.1| hypothetical protein BCG_3758 [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 58 more sequence titles
 
gi|148663563|ref|YP_001285086.1| hypothetical protein MRA_3735 [Mycobacterium tuberculosis H37Ra]
 gi|148824903|ref|YP_001289657.1| hypothetical protein TBFG_13730 [Mycobacterium tuberculosis F11]
 gi|167970852|ref|ZP_02553129.1| hypothetical protein MtubH3_23535 [Mycobacterium tuberculosis 
H37Ra]
 gi|224992110|ref|YP_002646799.1| hypothetical protein JTY_3760 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|254366244|ref|ZP_04982288.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|254552811|ref|ZP_05143258.1| hypothetical protein Mtube_20577 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|289445297|ref|ZP_06435041.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289572349|ref|ZP_06452576.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
 gi|289747537|ref|ZP_06506915.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289759856|ref|ZP_06519234.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|289763878|ref|ZP_06523256.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|294995391|ref|ZP_06801082.1| hypothetical protein Mtub2_12981 [Mycobacterium tuberculosis 
210]
 gi|298527175|ref|ZP_07014584.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|306778056|ref|ZP_07416393.1| hypothetical protein TMAG_00190 [Mycobacterium tuberculosis SUMu001]
 gi|306778588|ref|ZP_07416925.1| hypothetical protein TMBG_02237 [Mycobacterium tuberculosis SUMu002]
 gi|306786611|ref|ZP_07424933.1| hypothetical protein TMCG_01202 [Mycobacterium tuberculosis SUMu003]
 gi|306790977|ref|ZP_07429299.1| hypothetical protein TMDG_01434 [Mycobacterium tuberculosis SUMu004]
 gi|306791295|ref|ZP_07429597.1| hypothetical protein TMEG_00193 [Mycobacterium tuberculosis SUMu005]
 gi|306795361|ref|ZP_07433663.1| hypothetical protein TMFG_01931 [Mycobacterium tuberculosis SUMu006]
 gi|306801332|ref|ZP_07438000.1| hypothetical protein TMHG_02762 [Mycobacterium tuberculosis SUMu008]
 gi|306805543|ref|ZP_07442211.1| hypothetical protein TMGG_01241 [Mycobacterium tuberculosis SUMu007]
 gi|306969939|ref|ZP_07482600.1| hypothetical protein TMIG_00049 [Mycobacterium tuberculosis SUMu009]
 gi|306974173|ref|ZP_07486834.1| hypothetical protein TMJG_00950 [Mycobacterium tuberculosis SUMu010]
 gi|307081881|ref|ZP_07491051.1| hypothetical protein TMKG_00940 [Mycobacterium tuberculosis SUMu011]
 gi|307086494|ref|ZP_07495607.1| hypothetical protein TMLG_00188 [Mycobacterium tuberculosis SUMu012]
 gi|339633690|ref|YP_004725332.1| hypothetical protein MAF_37070 [Mycobacterium africanum GM041182]
 gi|2960123|emb|CAA18021.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|31620468|emb|CAD95911.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]
 gi|121495262|emb|CAL73748.1| Conserved hypothetical protein [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|134151756|gb|EBA43801.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|148507715|gb|ABQ75524.1| hypothetical protein MRA_3735 [Mycobacterium tuberculosis H37Ra]
 gi|148723430|gb|ABR08055.1| conserved hypothetical protein [Mycobacterium tuberculosis F11]
 gi|224775225|dbj|BAH28031.1| hypothetical protein JTY_3760 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|289418255|gb|EFD15456.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289536780|gb|EFD41358.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
 gi|289688065|gb|EFD55553.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289711384|gb|EFD75400.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|289715420|gb|EFD79432.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|298496969|gb|EFI32263.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|308213585|gb|EFO72984.1| hypothetical protein TMAG_00190 [Mycobacterium tuberculosis SUMu001]
 gi|308328317|gb|EFP17168.1| hypothetical protein TMBG_02237 [Mycobacterium tuberculosis SUMu002]
 gi|308328721|gb|EFP17572.1| hypothetical protein TMCG_01202 [Mycobacterium tuberculosis SUMu003]
 gi|308332563|gb|EFP21414.1| hypothetical protein TMDG_01434 [Mycobacterium tuberculosis SUMu004]
 gi|308340055|gb|EFP28906.1| hypothetical protein TMEG_00193 [Mycobacterium tuberculosis SUMu005]
 gi|308344044|gb|EFP32895.1| hypothetical protein TMFG_01931 [Mycobacterium tuberculosis SUMu006]
 gi|308347842|gb|EFP36693.1| hypothetical protein TMGG_01241 [Mycobacterium tuberculosis SUMu007]
 gi|308351830|gb|EFP40681.1| hypothetical protein TMHG_02762 [Mycobacterium tuberculosis SUMu008]
 gi|308352495|gb|EFP41346.1| hypothetical protein TMIG_00049 [Mycobacterium tuberculosis SUMu009]
 gi|308356445|gb|EFP45296.1| hypothetical protein TMJG_00950 [Mycobacterium tuberculosis SUMu010]
 gi|308360392|gb|EFP49243.1| hypothetical protein TMKG_00940 [Mycobacterium tuberculosis SUMu011]
 gi|308364088|gb|EFP52939.1| hypothetical protein TMLG_00188 [Mycobacterium tuberculosis SUMu012]
 gi|323717562|gb|EGB26764.1| hypothetical protein TMMG_00189 [Mycobacterium tuberculosis CDC1551A]
 gi|326905537|gb|EGE52470.1| hypothetical protein TBPG_03492 [Mycobacterium tuberculosis W-148]
 gi|339296508|gb|AEJ48619.1| hypothetical protein CCDC5079_3430 [Mycobacterium tuberculosis 
CCDC5079]
 gi|339300108|gb|AEJ52218.1| hypothetical protein CCDC5180_3381 [Mycobacterium tuberculosis 
CCDC5180]
 gi|339333046|emb|CCC28776.1| conserved hypothetical protein [Mycobacterium africanum GM041182]
 gi|341603635|emb|CCC66316.1| conserved hypothetical protein [Mycobacterium bovis BCG str. 
Moreau RDJ]
 gi|344221535|gb|AEN02166.1| hypothetical protein MTCTRI2_3769 [Mycobacterium tuberculosis 
CTRI-2]
Length=233

 Score =  470 bits (1210),  Expect = 6e-131, Method: Compositional matrix adjust.
 Identities = 233/233 (100%), Positives = 233/233 (100%), Gaps = 0/233 (0%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL
Sbjct  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST
Sbjct  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY
Sbjct  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG
Sbjct  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233


>gi|289441133|ref|ZP_06430877.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289755826|ref|ZP_06515204.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054]
 gi|289414052|gb|EFD11292.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289696413|gb|EFD63842.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054]
Length=233

 Score =  469 bits (1206),  Expect = 2e-130, Method: Compositional matrix adjust.
 Identities = 232/233 (99%), Positives = 233/233 (100%), Gaps = 0/233 (0%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL
Sbjct  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST
Sbjct  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY
Sbjct  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHD+KGRVKFPAYLLTAHKAG
Sbjct  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDKKGRVKFPAYLLTAHKAG  233


>gi|253800744|ref|YP_003033745.1| hypothetical protein TBMG_03742 [Mycobacterium tuberculosis KZN 
1435]
 gi|289555963|ref|ZP_06445173.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 
605]
 gi|297636377|ref|ZP_06954157.1| hypothetical protein MtubK4_19725 [Mycobacterium tuberculosis 
KZN 4207]
 gi|297733371|ref|ZP_06962489.1| hypothetical protein MtubKR_19865 [Mycobacterium tuberculosis 
KZN R506]
 gi|313660702|ref|ZP_07817582.1| hypothetical protein MtubKV_19860 [Mycobacterium tuberculosis 
KZN V2475]
 gi|253322247|gb|ACT26850.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 
1435]
 gi|289440595|gb|EFD23088.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 
605]
 gi|328460472|gb|AEB05895.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 
4207]
Length=233

 Score =  468 bits (1204),  Expect = 3e-130, Method: Compositional matrix adjust.
 Identities = 232/233 (99%), Positives = 232/233 (99%), Gaps = 0/233 (0%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MTDEVMDWDSAYREQGAFEG PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL
Sbjct  1    MTDEVMDWDSAYREQGAFEGAPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST
Sbjct  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY
Sbjct  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG
Sbjct  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233


>gi|340628672|ref|YP_004747124.1| hypothetical protein MCAN_37201 [Mycobacterium canettii CIPT 
140010059]
 gi|340006862|emb|CCC46051.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=233

 Score =  466 bits (1200),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 230/233 (99%), Positives = 232/233 (99%), Gaps = 0/233 (0%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MTDEVMDWDSAYREQG+F+GPPPWNIGEPQPELA LIAAGKVRSDVLDAGCGYAELSLAL
Sbjct  1    MTDEVMDWDSAYREQGSFDGPPPWNIGEPQPELAALIAAGKVRSDVLDAGCGYAELSLAL  60

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST
Sbjct  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY
Sbjct  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG
Sbjct  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233


>gi|183985179|ref|YP_001853470.1| hypothetical protein MMAR_5210 [Mycobacterium marinum M]
 gi|183178505|gb|ACC43615.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=232

 Score =  371 bits (953),  Expect = 4e-101, Method: Compositional matrix adjust.
 Identities = 192/232 (83%), Positives = 207/232 (90%), Gaps = 0/232 (0%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT  VMDWD AY++QGAFEGPPPWNIGEPQPELA LIAAGK+ SDVLDAGCGYAELSLAL
Sbjct  1    MTSPVMDWDDAYQQQGAFEGPPPWNIGEPQPELAALIAAGKIHSDVLDAGCGYAELSLAL  60

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA+GYTVVGID+TPTA+AAATKAA ERGL   SF+QADIT+F AYPAGSAGRF+TVIDST
Sbjct  61   AAEGYTVVGIDITPTAIAAATKAAAERGLGNTSFMQADITDFNAYPAGSAGRFATVIDST  120

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPV  RD YL SVHRAAAPGASY+VLVFAKGAFPA LE KPNEVDEDELRAAV KY
Sbjct  121  LFHSLPVSGRDDYLKSVHRAAAPGASYFVLVFAKGAFPAALETKPNEVDEDELRAAVGKY  180

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKA  232
            W+IDEIRPAFIH N   IPP  AG+P+EFPP+  DEKGR+KFPAYLLTAHKA
Sbjct  181  WEIDEIRPAFIHANVPVIPPLPAGSPIEFPPHQRDEKGRMKFPAYLLTAHKA  232


>gi|240173387|ref|ZP_04752045.1| hypothetical protein MkanA1_29001 [Mycobacterium kansasii ATCC 
12478]
Length=229

 Score =  363 bits (933),  Expect = 8e-99, Method: Compositional matrix adjust.
 Identities = 190/233 (82%), Positives = 206/233 (89%), Gaps = 4/233 (1%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT EVMDWD AYREQG FEGPPPWNIGEPQPELA LIAAGKVRSDVLDAGCG+AELSLAL
Sbjct  1    MTSEVMDWDGAYREQGVFEGPPPWNIGEPQPELAALIAAGKVRSDVLDAGCGFAELSLAL  60

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA+GYTVVGID+TPTAVAAAT+AA+ERGL+TASFVQADIT+FA YPA S GRF+TV+DST
Sbjct  61   AAEGYTVVGIDITPTAVAAATRAAQERGLSTASFVQADITDFAGYPARSEGRFATVLDST  120

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPV+ RD YL SVHRAAAPGA YYVLVFAKGAFPAE E +PNEVDEDELR AVSKY
Sbjct  121  LFHSLPVEDRDGYLRSVHRAAAPGACYYVLVFAKGAFPAEFEARPNEVDEDELRDAVSKY  180

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            W+IDEIRPAFIH N     PQ+ GAP E PP+  DEKGR+  PAYLL+AHKAG
Sbjct  181  WEIDEIRPAFIHAN----VPQVPGAPFEMPPHPRDEKGRMMLPAYLLSAHKAG  229


>gi|254821111|ref|ZP_05226112.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
intracellulare ATCC 13950]
Length=220

 Score =  358 bits (919),  Expect = 4e-97, Method: Compositional matrix adjust.
 Identities = 179/228 (79%), Positives = 195/228 (86%), Gaps = 8/228 (3%)

Query  6    MDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADGY  65
            MDWDSAYREQ  FEGPPPWNIGEPQPELA L AAGK RSDVLDAGCG AELSL+LAA GY
Sbjct  1    MDWDSAYREQAHFEGPPPWNIGEPQPELAALAAAGKFRSDVLDAGCGVAELSLSLAAQGY  60

Query  66   TVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSL  125
            TVVG+DLTPTAVAAATK+A+ERGLT ASFVQADIT  + Y     GRF+TV+DSTLFHSL
Sbjct  61   TVVGVDLTPTAVAAATKSAQERGLTRASFVQADITSLSGYD----GRFATVVDSTLFHSL  116

Query  126  PVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDE  185
            PV+ RD YL SVHRAAAPGASY+VLVFAKGAFPAE+E KPNEVDEDELRAAVS YW+IDE
Sbjct  117  PVEGRDGYLRSVHRAAAPGASYFVLVFAKGAFPAEMEPKPNEVDEDELRAAVSTYWEIDE  176

Query  186  IRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            IRP+FI  N + I    A AP EFPP+D DE+GR+K PAYLLTAHKAG
Sbjct  177  IRPSFILSNAINI----ADAPFEFPPHDRDEQGRIKMPAYLLTAHKAG  220


>gi|296166787|ref|ZP_06849207.1| thiopurine S-methyltransferase family protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295897858|gb|EFG77444.1| thiopurine S-methyltransferase family protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=226

 Score =  335 bits (859),  Expect = 3e-90, Method: Compositional matrix adjust.
 Identities = 183/231 (80%), Positives = 196/231 (85%), Gaps = 8/231 (3%)

Query  3    DEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAA  62
            D+VMDWD AYREQ  FEGPPPWNIGEPQPELA L AAGK RSDVLDAGCG AELSLALAA
Sbjct  4    DQVMDWDGAYREQAHFEGPPPWNIGEPQPELAALAAAGKFRSDVLDAGCGVAELSLALAA  63

Query  63   DGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLF  122
             GYTVVG+DLTPTAVAAAT+AA ERGLTTASF QADIT  + Y     GRFST++DSTLF
Sbjct  64   QGYTVVGVDLTPTAVAAATRAARERGLTTASFAQADITTLSGYD----GRFSTIVDSTLF  119

Query  123  HSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWK  182
            HSLPV+ RD YLSSVHRAAAPGA+ +VLVFAKGAFPAE+E KPNEVDEDELRAAV KYW+
Sbjct  120  HSLPVEGRDGYLSSVHRAAAPGAALFVLVFAKGAFPAEMEPKPNEVDEDELRAAVGKYWE  179

Query  183  IDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            +DEIRPAFI  N V IP     AP EFPP+D DEKGRVK PAYLLTAHKAG
Sbjct  180  VDEIRPAFILSNVVDIP----NAPFEFPPHDRDEKGRVKMPAYLLTAHKAG  226


>gi|41406399|ref|NP_959235.1| hypothetical protein MAP0301 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41394748|gb|AAS02618.1| hypothetical protein MAP_0301 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=229

 Score =  332 bits (851),  Expect = 3e-89, Method: Compositional matrix adjust.
 Identities = 176/231 (77%), Positives = 196/231 (85%), Gaps = 8/231 (3%)

Query  2    TDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALA  61
            +D+VMDWDSAYREQ  FEGPPPWNIGEPQPELA LI  GK RSDVLDAGCG+AELSLALA
Sbjct  6    SDQVMDWDSAYREQAHFEGPPPWNIGEPQPELAALIEQGKFRSDVLDAGCGFAELSLALA  65

Query  62   ADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTL  121
            A GYTVVGIDLTPTAVAAAT+AA ERGLTTASFVQADIT F  Y     GRF+TV+DSTL
Sbjct  66   ARGYTVVGIDLTPTAVAAATRAAAERGLTTASFVQADITSFTGYD----GRFATVVDSTL  121

Query  122  FHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYW  181
            FHSLPV+ RD YL S+HRAAA GAS ++LVFAKGAFPAE++ KPNEVDEDELRAAV KYW
Sbjct  122  FHSLPVEGRDGYLRSIHRAAAAGASLFILVFAKGAFPAEMQPKPNEVDEDELRAAVGKYW  181

Query  182  KIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKA  232
             ID+IRP+FI    V+  PQ+A AP EFP ++ DE+GR+K PAYLLTAHKA
Sbjct  182  AIDDIRPSFI----VSNVPQIADAPFEFPAHERDERGRMKMPAYLLTAHKA  228


>gi|118466516|ref|YP_879689.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium 104]
 gi|118167803|gb|ABK68700.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium 104]
Length=226

 Score =  330 bits (847),  Expect = 8e-89, Method: Compositional matrix adjust.
 Identities = 177/231 (77%), Positives = 195/231 (85%), Gaps = 8/231 (3%)

Query  2    TDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALA  61
            +D+VMDWDSAYREQ  FEGPPPWNIGEPQPELA LI  GK RSDVLDAGCG AELSLALA
Sbjct  3    SDQVMDWDSAYREQAHFEGPPPWNIGEPQPELAALIEQGKFRSDVLDAGCGCAELSLALA  62

Query  62   ADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTL  121
            A GYTVVGIDLTPTAVAAAT+AA ERGLTTASFVQADIT F  Y     GRF+TV+DSTL
Sbjct  63   ARGYTVVGIDLTPTAVAAATRAAAERGLTTASFVQADITSFTGYD----GRFATVVDSTL  118

Query  122  FHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYW  181
            FHSLPV+ RD YL S+HRAAA GAS ++LVFAKGAFPAE++ KPNEVDEDELRAAV KYW
Sbjct  119  FHSLPVEGRDGYLRSIHRAAAAGASLFILVFAKGAFPAEMQPKPNEVDEDELRAAVGKYW  178

Query  182  KIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKA  232
             IDEIRP+FI    V+  PQ+A AP EFP ++ DE+GR+K PAYLLTAHKA
Sbjct  179  VIDEIRPSFI----VSNVPQIADAPFEFPAHERDERGRMKMPAYLLTAHKA  225


>gi|254773409|ref|ZP_05214925.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium subsp. avium ATCC 25291]
Length=220

 Score =  327 bits (838),  Expect = 9e-88, Method: Compositional matrix adjust.
 Identities = 175/227 (78%), Positives = 192/227 (85%), Gaps = 8/227 (3%)

Query  6    MDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADGY  65
            MDWDSAYREQ  FEGPPPWNIGEPQ ELA LI  GK RSDVLDAGCG+AELSLALAA GY
Sbjct  1    MDWDSAYREQAHFEGPPPWNIGEPQSELAALIEQGKFRSDVLDAGCGFAELSLALAARGY  60

Query  66   TVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSL  125
            TVVGIDLTPTAVAAAT+AA ERGLTTASFVQADIT F  Y     GRF+TV+DSTLFHSL
Sbjct  61   TVVGIDLTPTAVAAATRAAAERGLTTASFVQADITSFTGYD----GRFATVVDSTLFHSL  116

Query  126  PVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDE  185
            PV+ RD YL S+HRAAAPGAS ++LVFAKGAFPAE++ KPNEVDEDELRAAV KYW IDE
Sbjct  117  PVEGRDGYLRSIHRAAAPGASLFILVFAKGAFPAEMQPKPNEVDEDELRAAVGKYWVIDE  176

Query  186  IRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKA  232
            IRP+FI    V+  PQ+A AP EFP ++ DE+GR+K PAYLLTAHKA
Sbjct  177  IRPSFI----VSNVPQIADAPFEFPAHERDERGRMKMPAYLLTAHKA  219


>gi|336460875|gb|EGO39760.1| Thiopurine S-methyltransferase (TPMT) [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=220

 Score =  325 bits (833),  Expect = 3e-87, Method: Compositional matrix adjust.
 Identities = 174/227 (77%), Positives = 192/227 (85%), Gaps = 8/227 (3%)

Query  6    MDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADGY  65
            MDWDSAYREQ  FEGPPPWNIGEPQPELA LI  GK RSDVLDAGCG+AELSLALAA GY
Sbjct  1    MDWDSAYREQAHFEGPPPWNIGEPQPELAALIEQGKFRSDVLDAGCGFAELSLALAARGY  60

Query  66   TVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSL  125
            TVVGIDLTPTAVAAAT+AA ERGLTTASFVQADIT F  Y     GRF+TV+DSTLFHSL
Sbjct  61   TVVGIDLTPTAVAAATRAAAERGLTTASFVQADITSFTGYD----GRFATVVDSTLFHSL  116

Query  126  PVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDE  185
            PV+ RD YL S+H+AAA GAS ++LVFAKGAFPAE++ KPNEVDEDELRAAV KYW IDE
Sbjct  117  PVEGRDGYLRSIHQAAAAGASLFILVFAKGAFPAEMQPKPNEVDEDELRAAVGKYWAIDE  176

Query  186  IRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKA  232
            IRP+FI    V+  PQ+A AP EFP ++ DE+GR+K PAYLLTAHKA
Sbjct  177  IRPSFI----VSNVPQIADAPFEFPAHERDERGRMKMPAYLLTAHKA  219


>gi|342861937|ref|ZP_08718581.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
colombiense CECT 3035]
 gi|342130477|gb|EGT83786.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
colombiense CECT 3035]
Length=216

 Score =  323 bits (827),  Expect = 2e-86, Method: Compositional matrix adjust.
 Identities = 179/228 (79%), Positives = 189/228 (83%), Gaps = 12/228 (5%)

Query  6    MDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADGY  65
            MDWDSAYREQ  FEGPPPWNIGEPQPELA LIAAGK RSDVLDAGCG AELSL LAA GY
Sbjct  1    MDWDSAYREQAHFEGPPPWNIGEPQPELAALIAAGKFRSDVLDAGCGVAELSLTLAAQGY  60

Query  66   TVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSL  125
            TVVGIDLTPTAVAAATKAA +RGLTTA+FVQADIT F  Y     GRFSTV DSTLFHSL
Sbjct  61   TVVGIDLTPTAVAAATKAAADRGLTTATFVQADITSFTGYD----GRFSTVADSTLFHSL  116

Query  126  PVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDE  185
            P++ RD YLS+VHRAAAPGA ++VLVFAKGAFP E E KPNEVDEDELR AVSKYW+IDE
Sbjct  117  PIEGRDGYLSAVHRAAAPGARFFVLVFAKGAFPDEWEAKPNEVDEDELRDAVSKYWEIDE  176

Query  186  IRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            IRPAFIH N   IPP   G     P +D DEKGR+K PAYLLTAHKAG
Sbjct  177  IRPAFIHAN---IPPVPDG-----PKHDRDEKGRMKMPAYLLTAHKAG  216


>gi|289748214|ref|ZP_06507592.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|289688801|gb|EFD56230.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
Length=175

 Score =  319 bits (818),  Expect = 2e-85, Method: Compositional matrix adjust.
 Identities = 159/160 (99%), Positives = 160/160 (100%), Gaps = 0/160 (0%)

Query  74   PTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSLPVDSRDRY  133
            PTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSLPVDSRDRY
Sbjct  16   PTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSLPVDSRDRY  75

Query  134  LSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDEIRPAFIHV  193
            LSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDEIRPAFIHV
Sbjct  76   LSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDEIRPAFIHV  135

Query  194  NPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            NPVTIPPQLAGAPVEFPPYDHD+KGRVKFPAYLLTAHKAG
Sbjct  136  NPVTIPPQLAGAPVEFPPYDHDKKGRVKFPAYLLTAHKAG  175


>gi|108801840|ref|YP_642037.1| type 12 methyltransferase [Mycobacterium sp. MCS]
 gi|119870993|ref|YP_940945.1| type 12 methyltransferase [Mycobacterium sp. KMS]
 gi|126437808|ref|YP_001073499.1| type 12 methyltransferase [Mycobacterium sp. JLS]
 gi|108772259|gb|ABG10981.1| Methyltransferase type 12 [Mycobacterium sp. MCS]
 gi|119697082|gb|ABL94155.1| Methyltransferase type 12 [Mycobacterium sp. KMS]
 gi|126237608|gb|ABO01009.1| Methyltransferase type 12 [Mycobacterium sp. JLS]
Length=227

 Score =  316 bits (809),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 163/231 (71%), Positives = 189/231 (82%), Gaps = 9/231 (3%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT +VM+WD AYR  G+FEGPPPWNIGEPQPELA L   G+ RS VLDAGCG+AELSLAL
Sbjct  1    MTSDVMNWDDAYRSAGSFEGPPPWNIGEPQPELAALHREGRFRSPVLDAGCGHAELSLAL  60

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AADGYTVVG+D++PTA+AAA +AA+ER L TASFVQ DIT F  Y     GRF+TV+DST
Sbjct  61   AADGYTVVGMDISPTAIAAADRAAQERSLATASFVQVDITSFTGY----DGRFNTVVDST  116

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPV+ RD YLSSVHRAAAPGA  ++LVFAKGAFP +LEVKP+EVDEDELRAAVS+Y
Sbjct  117  LFHSLPVEGRDGYLSSVHRAAAPGAQLFILVFAKGAFPPDLEVKPHEVDEDELRAAVSRY  176

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHK  231
            W+ID++RPAFIH N + +P      P E  P+  DEK RVKFPA+LLTAHK
Sbjct  177  WEIDDVRPAFIHANALAMP----DLPAEL-PHGPDEKNRVKFPAFLLTAHK  222


>gi|118467923|ref|YP_890454.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
smegmatis str. MC2 155]
 gi|118169210|gb|ABK70106.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
smegmatis str. MC2 155]
Length=226

 Score =  313 bits (801),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 160/231 (70%), Positives = 185/231 (81%), Gaps = 9/231 (3%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT  V+DWD AYR    F+GPPPWNIGEPQPELA L  AG+ RSDVLDAGCG+AELSLAL
Sbjct  4    MTSHVLDWDGAYRGDTGFQGPPPWNIGEPQPELAALHRAGRFRSDVLDAGCGHAELSLAL  63

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AADGYTVVG+DL+P+A+AAA +AA+ER L TASFVQ DIT F  Y     GRFSTVIDST
Sbjct  64   AADGYTVVGMDLSPSAIAAANRAAQERNLATASFVQGDITSFTGY----DGRFSTVIDST  119

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHSLPV+ R+ YL S+HRA+APGA Y+VLVFAKGAFPA+LEVKPNEV E+ELR  V KY
Sbjct  120  LFHSLPVEGREGYLQSIHRASAPGARYFVLVFAKGAFPADLEVKPNEVTEEELRTTVGKY  179

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHK  231
            W +D+IRPAFIH N V  P     AP E PP+ +D+KGR+ FPA+LL AH+
Sbjct  180  WVVDDIRPAFIHANAVVFP----DAP-ELPPHGYDDKGRIMFPAFLLEAHR  225


>gi|120406418|ref|YP_956247.1| type 11 methyltransferase [Mycobacterium vanbaalenii PYR-1]
 gi|119959236|gb|ABM16241.1| Methyltransferase type 11 [Mycobacterium vanbaalenii PYR-1]
Length=227

 Score =  273 bits (697),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 155/232 (67%), Positives = 178/232 (77%), Gaps = 11/232 (4%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MTD VMDWDSAYR +G FEG PPWNIGEPQPELA L   GK RS+VLDAGCG+AELSLAL
Sbjct  4    MTD-VMDWDSAYRGEGDFEGEPPWNIGEPQPELAALWRDGKFRSEVLDAGCGHAELSLAL  62

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLT-TASFVQADITEFAAYPAGSAGRFSTVIDS  119
            AADGYTV G+DL+PTAVAAAT A+ ERGL+   SFV ADIT    +     GRF+TV+DS
Sbjct  63   AADGYTVTGVDLSPTAVAAATAASAERGLSERTSFVAADITTLTGFD----GRFATVVDS  118

Query  120  TLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSK  179
            TLFHSLPV+SRD YL SVHRAAAPGA Y+VLVFAKGAFPAE+E  PNEV E ELR AVS+
Sbjct  119  TLFHSLPVESRDGYLQSVHRAAAPGAGYFVLVFAKGAFPAEMEGGPNEVTELELREAVSR  178

Query  180  YWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHK  231
            YW ID+IRPA I  N V   P +   P++      D++GR++  A+LL AHK
Sbjct  179  YWIIDDIRPALIDTN-VPKLPGMPPPPLDML----DDRGRLRMQAFLLQAHK  225


>gi|240168945|ref|ZP_04747604.1| hypothetical protein MkanA1_06510 [Mycobacterium kansasii ATCC 
12478]
Length=234

 Score =  271 bits (693),  Expect = 6e-71, Method: Compositional matrix adjust.
 Identities = 147/240 (62%), Positives = 178/240 (75%), Gaps = 13/240 (5%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            M  E+MDW++AYRE G F GPPPWNIGEPQPE+A LI AGK+RS+VLDAGCG AELSLAL
Sbjct  1    MNGELMDWEAAYREHGVFGGPPPWNIGEPQPEIAALIRAGKIRSEVLDAGCGVAELSLAL  60

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA G+TV+G+D++ TA+A A +AA +RGL+T +FVQ D+T    Y     GRF+T+IDST
Sbjct  61   AALGHTVMGVDVSGTAIAKAKQAATDRGLSTVTFVQDDLTSLDGYD----GRFNTIIDST  116

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEV-------KPNEVDEDEL  173
            LF SLPVDSRD Y+ SVHRAAAPGASYYVL     A PA++E+        PN V E EL
Sbjct  117  LFESLPVDSRDDYIRSVHRAAAPGASYYVLASTATALPADIELPPDAPAAPPNLVTETEL  176

Query  174  RAAVSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
            R AVS+YW IDEIRPAFIHV+   +  ++ G  V    Y+ DE+ RVK  A+LLTAHKAG
Sbjct  177  REAVSRYWAIDEIRPAFIHVHLAEVLSRIPG--VSLADYEVDERNRVKVSAFLLTAHKAG  234


>gi|145221916|ref|YP_001132594.1| type 11 methyltransferase [Mycobacterium gilvum PYR-GCK]
 gi|315446348|ref|YP_004079227.1| methyltransferase family protein [Mycobacterium sp. Spyr1]
 gi|145214402|gb|ABP43806.1| Methyltransferase type 11 [Mycobacterium gilvum PYR-GCK]
 gi|315264651|gb|ADU01393.1| methyltransferase family protein [Mycobacterium sp. Spyr1]
Length=224

 Score =  268 bits (684),  Expect = 5e-70, Method: Compositional matrix adjust.
 Identities = 148/229 (65%), Positives = 175/229 (77%), Gaps = 10/229 (4%)

Query  4    EVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAAD  63
            EVMDWDSAYR +G FEG PPWNIGEPQPELA L   G+ RS+VLDAGCG+AELSLALAAD
Sbjct  3    EVMDWDSAYRGEGEFEGEPPWNIGEPQPELAALWRDGRFRSEVLDAGCGHAELSLALAAD  62

Query  64   GYTVVGIDLTPTAVAAATKAAEERGLT-TASFVQADITEFAAYPAGSAGRFSTVIDSTLF  122
            GYTV G+D++PTA+AAA+ AA ERGL+  ASFV ADIT  + +     GRFSTV+DSTLF
Sbjct  63   GYTVTGVDISPTAMAAASAAAAERGLSEKASFVAADITALSGFD----GRFSTVVDSTLF  118

Query  123  HSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWK  182
            HSLPV+SR  YL SVHRAA PGA ++VLVFAKGAFPA+ E  PNEV E ELR AVS YW 
Sbjct  119  HSLPVESRAGYLESVHRAARPGAGFFVLVFAKGAFPADTEQGPNEVSEIELREAVSPYWT  178

Query  183  IDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHK  231
            ID+IRPA IH N V   P +   P++      D++G ++  A+LL+AHK
Sbjct  179  IDDIRPALIHTN-VPKLPGMPPPPLDML----DDRGHLRMQAFLLSAHK  222


>gi|317506538|ref|ZP_07964335.1| methyltransferase domain-containing protein [Segniliparus rugosus 
ATCC BAA-974]
 gi|316255177|gb|EFV14450.1| methyltransferase domain-containing protein [Segniliparus rugosus 
ATCC BAA-974]
Length=225

 Score =  249 bits (637),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 141/231 (62%), Positives = 161/231 (70%), Gaps = 10/231 (4%)

Query  6    MDWDSAYR-EQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            M+WD  YR E     G PPWNIGEPQPE+  LI AG+    VLDAGCG+AE SL LAA G
Sbjct  1    MEWDEVYRGESDRISGEPPWNIGEPQPEINALIEAGEFHGTVLDAGCGHAETSLKLAALG  60

Query  65   YTVVGIDLTPTAVAAATKAAEERGLT-TASFVQADITEFAAYPAGSAGRFSTVIDSTLFH  123
            YTVVG+DL+PTA+AAATK+AEERGL+  A++  ADI+ F  Y     GRF T++DSTLFH
Sbjct  61   YTVVGLDLSPTAIAAATKSAEERGLSDRATYEVADISSFTGYD----GRFDTIVDSTLFH  116

Query  124  SLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKI  183
            S+PV+ R+ YLSS+ RAAAPGA Y VLVF K A P E    PN VDE ELR  VSKYW I
Sbjct  117  SMPVEFREGYLSSILRAAAPGAKYVVLVFDKLAIP-EGVPGPNGVDEAELREIVSKYWAI  175

Query  184  DEIRPAFIHVN--PVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKA  232
            DEIRPAFIH N  P      L    V FP    DEKGR+K PA+LL AHKA
Sbjct  176  DEIRPAFIHANMDPDRFKALLPEG-VSFPERPRDEKGRMKSPAWLLKAHKA  225


>gi|169628058|ref|YP_001701707.1| hypothetical protein MAB_0961c [Mycobacterium abscessus ATCC 
19977]
 gi|169240025|emb|CAM61053.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=225

 Score =  249 bits (636),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 138/231 (60%), Positives = 168/231 (73%), Gaps = 10/231 (4%)

Query  2    TDEVMDWDSAYREQGA-FEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            ++E+ DWD+ Y+ +G  F+G PPWNIGEPQPELA LI AGK    VLD GCG+AE SL L
Sbjct  3    SNELPDWDATYQGKGELFQGEPPWNIGEPQPELAALIDAGKFHGTVLDVGCGHAETSLRL  62

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA G+T VG+DL+PTA+ AA  AA ERGLT A+F  ADIT+F+ Y     GRF+T++DST
Sbjct  63   AALGHTTVGLDLSPTAIEAARAAAAERGLTNATFEVADITDFSGY----DGRFNTIVDST  118

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKY  180
            LFHS+PV++R+ YL S+ RAAAP ASY+VLVFA GAFP    + PN V EDELRAAV  Y
Sbjct  119  LFHSIPVEAREAYLQSISRAAAPDASYFVLVFAVGAFPP--GIGPNAVTEDELRAAVEPY  176

Query  181  WKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHK  231
            W IDE+  A+IH N   IP  + GA  E P +  DEKGR K PA+LL AHK
Sbjct  177  WAIDELSSAYIHSN---IPEVIPGANFEMPVFHKDEKGRNKQPAFLLQAHK  224


>gi|296393423|ref|YP_003658307.1| type 11 methyltransferase [Segniliparus rotundus DSM 44985]
 gi|296180570|gb|ADG97476.1| Methyltransferase type 12 [Segniliparus rotundus DSM 44985]
Length=232

 Score =  234 bits (597),  Expect = 7e-60, Method: Compositional matrix adjust.
 Identities = 143/237 (61%), Positives = 167/237 (71%), Gaps = 12/237 (5%)

Query  1    MTD--EVMDWDSAYR-EQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELS  57
            MTD  +V DWDS YR E    +G PPWNIGEPQPE+  LI AG+V   VLDAGCG+AE S
Sbjct  1    MTDANQVADWDSIYRGESEHLKGEPPWNIGEPQPEINALIEAGEVTGAVLDAGCGHAETS  60

Query  58   LALAADGYTVVGIDLTPTAVAAATKAAEERGLT-TASFVQADITEFAAYPAGSAGRFSTV  116
            L LAA G+TVVG+DL+PTA+AAA KAAE+RGL+  A++  ADI+ F  Y     GRF T+
Sbjct  61   LKLAALGHTVVGLDLSPTAIAAARKAAEKRGLSDKAAYETADISSFTGYD----GRFDTI  116

Query  117  IDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAA  176
            IDSTLFHS+PV+ R+ YLSS+ RAAAPGA Y VLVF K AFP  +   PN VD+ ELR  
Sbjct  117  IDSTLFHSMPVELREGYLSSILRAAAPGAKYIVLVFDKNAFPEGMG-GPNGVDDTELREL  175

Query  177  VSKYWKIDEIRPAFIHVNPVTIPPQLAGAP--VEFPPYDHDEKGRVKFPAYLLTAHK  231
            VSKYW +DEIRPAFIH N +         P  V FP Y  DEKGR K PA+LL AHK
Sbjct  176  VSKYWTVDEIRPAFIHAN-LDWANMHDALPEGVVFPEYPKDEKGRSKAPAWLLRAHK  231


>gi|111020498|ref|YP_703470.1| methyltransferase [Rhodococcus jostii RHA1]
 gi|110820028|gb|ABG95312.1| possible methyltransferase [Rhodococcus jostii RHA1]
Length=220

 Score =  234 bits (597),  Expect = 8e-60, Method: Compositional matrix adjust.
 Identities = 141/229 (62%), Positives = 168/229 (74%), Gaps = 16/229 (6%)

Query  3    DEVMDWDSAYR-EQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALA  61
            ++V  WD  YR +   F GP PWNIGEPQPE+A LIA GK RSDVLDAGCG+AE SL LA
Sbjct  5    NQVAPWDDIYRGDAEVFTGPVPWNIGEPQPEIAGLIAEGKFRSDVLDAGCGHAETSLQLA  64

Query  62   ADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTL  121
              GYTVVG+DL+PTA+A A  AA +RGLTTA++  ADI+ F  +     GRFST++DSTL
Sbjct  65   EQGYTVVGLDLSPTAIAVAQAAAADRGLTTATYQVADISSFTGFD----GRFSTIVDSTL  120

Query  122  FHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYW  181
            FHSLPVD R  YL +V RAAAPGASYY+LVFAKGAFP E E  PN V +DELR AV+++W
Sbjct  121  FHSLPVDRRRDYLRAVARAAAPGASYYILVFAKGAFP-EGE-GPNPVTDDELREAVAEFW  178

Query  182  KIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAH  230
             ID+IRPAFIH   +  P Q A        ++HDEKGR K PA+LL+AH
Sbjct  179  TIDDIRPAFIHA--LLGPEQAAN-------WEHDEKGRSKLPAWLLSAH  218


>gi|226362123|ref|YP_002779901.1| hypothetical protein ROP_27090 [Rhodococcus opacus B4]
 gi|226240608|dbj|BAH50956.1| hypothetical protein [Rhodococcus opacus B4]
Length=220

 Score =  228 bits (580),  Expect = 7e-58, Method: Compositional matrix adjust.
 Identities = 137/230 (60%), Positives = 166/230 (73%), Gaps = 16/230 (6%)

Query  3    DEVMDWDSAYR-EQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALA  61
            ++V  WD  YR +   F GP PWNIGEPQPE+A LIA GK RSDVLDAGCG+AE SL LA
Sbjct  5    NQVAPWDDIYRGDAKEFAGPVPWNIGEPQPEIAALIAEGKFRSDVLDAGCGHAETSLRLA  64

Query  62   ADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTL  121
            A GYTVVG+DL+PTA+AAA  AA +RGLTTA++  ADI+ F  +     GRF+T++DSTL
Sbjct  65   AQGYTVVGLDLSPTAIAAAQAAAADRGLTTATYQVADISTFTGFD----GRFATIVDSTL  120

Query  122  FHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYW  181
            FHSLPVD R  YL +V RAAAPGASYY+LVFAKGAFP      PN V ++ELR AV++YW
Sbjct  121  FHSLPVDRRRDYLQAVARAAAPGASYYILVFAKGAFPE--GQGPNPVTDEELREAVAEYW  178

Query  182  KIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHK  231
             ID++RPAFIH         L G P E   +  D+KGR   PA+LL+AH+
Sbjct  179  IIDDLRPAFIHA--------LLG-PEEAANWQRDDKGRAMLPAWLLSAHR  219


>gi|183980930|ref|YP_001849221.1| methyltransferase [Mycobacterium marinum M]
 gi|183174256|gb|ACC39366.1| methyltransferase [Mycobacterium marinum M]
Length=229

 Score =  225 bits (573),  Expect = 5e-57, Method: Compositional matrix adjust.
 Identities = 132/234 (57%), Positives = 167/234 (72%), Gaps = 11/234 (4%)

Query  1    MTDEV-MDWDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAEL  56
            MT+ + + +++AYR + A  G    PPW++GEPQPELATLI  GKV  +VLDAGCG A L
Sbjct  1    MTESLDLQFETAYRGESAEFGAGIRPPWSLGEPQPELATLIEQGKVHGEVLDAGCGEAAL  60

Query  57   SLALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTV  116
            +LALA  G+ VVG+D++PTAV  A + A  RGLT ASF  ADIT+FA+YP  SAGRF+T+
Sbjct  61   ALALAGRGHPVVGLDMSPTAVELAGREAARRGLTNASFAVADITDFASYPPESAGRFNTI  120

Query  117  IDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAA  176
            +DSTLFHS+PV+ R+ Y  S+ RAAAPGASY+VLVF K A   +  +  N V E+ELR A
Sbjct  121  MDSTLFHSMPVELREGYQRSIVRAAAPGASYFVLVFDKAALSGDGPI--NGVTEEELRDA  178

Query  177  VSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAH  230
            VSKYW IDEIRPA IH N   +PP+++G P  F   D  E GR    A+LL+AH
Sbjct  179  VSKYWVIDEIRPARIHAN---LPPEVSGMPA-FDARDEPE-GRKSVGAWLLSAH  227


>gi|240172077|ref|ZP_04750736.1| hypothetical protein MkanA1_22365 [Mycobacterium kansasii ATCC 
12478]
Length=228

 Score =  222 bits (565),  Expect = 4e-56, Method: Compositional matrix adjust.
 Identities = 121/226 (54%), Positives = 151/226 (67%), Gaps = 11/226 (4%)

Query  8    WDSAYREQ--GAFEGP-PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            ++SAYR +      GP PPW+IGEPQPELA LI  GK   DVLDAGCG A +SL LA  G
Sbjct  9    FESAYRGEVPSLGSGPKPPWSIGEPQPELAALIEQGKFHGDVLDAGCGEAAISLQLAELG  68

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            YT VG+DL+PTA+  A   A +RGL+ A+F  ADI++F  YP GS GRF T++DSTLFHS
Sbjct  69   YTTVGLDLSPTAIELARAEAAKRGLSNATFAVADISDFTGYPPGSEGRFGTIVDSTLFHS  128

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            LPV++R+ YL SV RAAAPGASY+VLVF + + P   E   N V EDELR  V +YW ID
Sbjct  129  LPVEAREGYLQSVVRAAAPGASYFVLVFDRASMP---EGPANAVTEDELRELVGRYWAID  185

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAH  230
            EI+PA +H N   +P   +  P+       +  GR   P +LL+AH
Sbjct  186  EIKPARLHGN---LPESFSALPLG--DLRDEPNGRKSVPGWLLSAH  226


>gi|118616465|ref|YP_904797.1| methyltransferase [Mycobacterium ulcerans Agy99]
 gi|118568575|gb|ABL03326.1| methyltransferase [Mycobacterium ulcerans Agy99]
Length=243

 Score =  217 bits (553),  Expect = 9e-55, Method: Compositional matrix adjust.
 Identities = 118/210 (57%), Positives = 151/210 (72%), Gaps = 9/210 (4%)

Query  1    MTDEV-MDWDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAEL  56
            MT+ + + + +AYR + A  G    PPW++GEPQPELATLI  GKV  +VLDAGCG A L
Sbjct  1    MTESLDLQFATAYRGESAEFGAGIRPPWSLGEPQPELATLIEQGKVHGEVLDAGCGEAAL  60

Query  57   SLALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTV  116
            ++ALA  G+ VVG+D++PTAV  A + A   GLT ASF  ADIT+FA+YP  SAGRF+T+
Sbjct  61   AMALAGRGHPVVGLDISPTAVELAGREAARPGLTNASFAVADITDFASYPPESAGRFNTI  120

Query  117  IDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAA  176
            +DSTLFHS+PV+ R+    S+ RAAAPGASY+VLVF K A   +  +  N V E+ELR A
Sbjct  121  MDSTLFHSMPVELREGCQRSIVRAAAPGASYFVLVFDKAALSGDGPI--NGVTEEELRDA  178

Query  177  VSKYWKIDEIRPAFIHVNPVTIPPQLAGAP  206
            VSK+W IDEIRPA IH N   +PP++ G P
Sbjct  179  VSKHWVIDEIRPARIHAN---LPPEVPGCP  205


>gi|169627497|ref|YP_001701146.1| methyltransferase [Mycobacterium abscessus ATCC 19977]
 gi|169239464|emb|CAM60492.1| Possible methyltransferase [Mycobacterium abscessus]
Length=232

 Score =  216 bits (549),  Expect = 3e-54, Method: Compositional matrix adjust.
 Identities = 128/241 (54%), Positives = 152/241 (64%), Gaps = 17/241 (7%)

Query  1    MTDEV------MDWDSAYREQG--AFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCG  52
            MTD+       + +D+AYR +        PPW+IGEPQPE+A LIA GKVR +VLDAGCG
Sbjct  1    MTDKTATEEFDLAFDAAYRGEAPDGRGARPPWSIGEPQPEIAMLIAEGKVRGEVLDAGCG  60

Query  53   YAELSLALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGR  112
             A  SL LA  G+T VG+D  P A+  A   A ERGLT ASF  ADI+ F  Y     GR
Sbjct  61   EAATSLYLAEVGHTTVGLDSAPKAIELAKGYAAERGLTNASFAVADISSFTGYD----GR  116

Query  113  FSTVIDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDE  172
            F T+IDSTLFHS+PV  R  Y  S+ RAAAPGA YYVLVF + AFPAE  V  N V E+E
Sbjct  117  FDTIIDSTLFHSMPVGLRAGYQRSIVRAAAPGARYYVLVFDRAAFPAESPV--NAVTENE  174

Query  173  LRAAVSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKA  232
            LR AVSKYW IDEIRPA I+ N     P +A     F  ++ +  GR    A+LL+AH A
Sbjct  175  LRDAVSKYWAIDEIRPAKIYANFNGFEPGVARG---FARHEIEPDGRASVAAWLLSAHLA  231

Query  233  G  233
            G
Sbjct  232  G  232


>gi|342860173|ref|ZP_08716825.1| hypothetical protein MCOL_14880 [Mycobacterium colombiense CECT 
3035]
 gi|342132551|gb|EGT85780.1| hypothetical protein MCOL_14880 [Mycobacterium colombiense CECT 
3035]
Length=229

 Score =  213 bits (543),  Expect = 1e-53, Method: Compositional matrix adjust.
 Identities = 123/228 (54%), Positives = 148/228 (65%), Gaps = 14/228 (6%)

Query  8    WDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            ++SAYR +    G    PPW+IGEPQPE+A LI  GK   DVLDAGCG A +SL LA  G
Sbjct  9    FESAYRGEAPEMGEGNRPPWSIGEPQPEIAALIEDGKFHGDVLDAGCGEAAVSLFLAERG  68

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            +T VG+D +PTA+A AT+ A  RGLT A+F  ADI++FA Y     GRF T++DSTLFHS
Sbjct  69   FTTVGLDQSPTAIALATEKAARRGLTRATFDVADISDFAGYD----GRFGTIVDSTLFHS  124

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            +PV+ RD Y  S+ RAAAPGASY+VLVF + A PAE  V  N V E ELR  VSKYW ID
Sbjct  125  MPVELRDGYQQSIVRAAAPGASYFVLVFDRAAMPAEGPV--NAVTEPELREVVSKYWVID  182

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYD--HDEKGRVKFPAYLLTAH  230
            EIRP  IH N   +P         F   D   +E GR    A+LL+AH
Sbjct  183  EIRPVRIHAN---VPESFLAGFEAFAGADIRDEENGRKSVGAWLLSAH  227


>gi|41406223|ref|NP_959059.1| hypothetical protein MAP0125c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41394571|gb|AAS02442.1| hypothetical protein MAP_0125c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=231

 Score =  212 bits (540),  Expect = 3e-53, Method: Compositional matrix adjust.
 Identities = 120/228 (53%), Positives = 148/228 (65%), Gaps = 14/228 (6%)

Query  8    WDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            +++AYR +    G    PPW+IGEPQPE+A LI AGK   DVLDAGCG A +SL LA  G
Sbjct  11   FEAAYRGESPEMGEGARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYLAERG  70

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            +T VG+D +PTA+  A + A  RGLT+ASF  ADI++F  Y     GRF T++DSTLFHS
Sbjct  71   FTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYD----GRFGTIVDSTLFHS  126

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            +PV+ R+ Y  S+ RAAAPGASY+VLVF + A PAE  V  N V EDELR  V KYW ID
Sbjct  127  MPVELREGYQRSIVRAAAPGASYFVLVFDRNAMPAEGPV--NAVTEDELREVVGKYWVID  184

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYD--HDEKGRVKFPAYLLTAH  230
            EIRPA IH N   +P         F   D   ++ GR    A+LL+AH
Sbjct  185  EIRPARIHAN---VPENFLAGFEAFAGADIRDEDNGRKSVGAWLLSAH  229


>gi|340625587|ref|YP_004744039.1| putative benzoquinone methyltransferase [Mycobacterium canettii 
CIPT 140010059]
 gi|340003777|emb|CCC42903.1| putative benzoquinone methyltransferase (methylase) [Mycobacterium 
canettii CIPT 140010059]
Length=241

 Score =  212 bits (540),  Expect = 3e-53, Method: Compositional matrix adjust.
 Identities = 126/234 (54%), Positives = 153/234 (66%), Gaps = 15/234 (6%)

Query  1    MTDEV-MDWDSAYR-EQGAF-EG-PPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAEL  56
            MT+ + ++++SAYR E  AF EG  PPW+IGEPQPELA LI  GK R DVLD GCG A +
Sbjct  17   MTESLDLEFESAYRGESVAFGEGVRPPWSIGEPQPELAALIVQGKFRGDVLDVGCGEAAI  76

Query  57   SLALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTV  116
            SLALA  G+T VG+DL+PTAV  A   A +RGL  ASF  AD + F  Y     GRF T+
Sbjct  77   SLALAERGHTTVGLDLSPTAVELARHEAAKRGLANASFEVADASSFTGYD----GRFDTI  132

Query  117  IDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAA  176
            +DSTLFHS+PV+SR+ YL S+ RAAAPGASY+VLVF + A P   E   N V EDELRAA
Sbjct  133  VDSTLFHSMPVESREGYLQSIVRAAAPGASYFVLVFDRAAIP---EGPINAVTEDELRAA  189

Query  177  VSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAH  230
            VSKYW IDEI+PA ++      P   AG P        +  G      +LL+AH
Sbjct  190  VSKYWIIDEIKPARLYAR---FPAGFAGMPA-LLDIREEPNGLQSIGGWLLSAH  239


>gi|336458089|gb|EGO37075.1| Thiopurine S-methyltransferase (TPMT) [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=222

 Score =  212 bits (539),  Expect = 4e-53, Method: Compositional matrix adjust.
 Identities = 120/228 (53%), Positives = 148/228 (65%), Gaps = 14/228 (6%)

Query  8    WDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            +++AYR +    G    PPW+IGEPQPE+A LI AGK   DVLDAGCG A +SL LA  G
Sbjct  2    FEAAYRGESPEMGEGARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYLAERG  61

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            +T VG+D +PTA+  A + A  RGLT+ASF  ADI++F  Y     GRF T++DSTLFHS
Sbjct  62   FTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYD----GRFGTIVDSTLFHS  117

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            +PV+ R+ Y  S+ RAAAPGASY+VLVF + A PAE  V  N V EDELR  V KYW ID
Sbjct  118  MPVELREGYQRSIVRAAAPGASYFVLVFDRNAMPAEGPV--NAVTEDELREVVGKYWVID  175

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYD--HDEKGRVKFPAYLLTAH  230
            EIRPA IH N   +P         F   D   ++ GR    A+LL+AH
Sbjct  176  EIRPARIHAN---VPENFLAGFEAFAGADIRDEDNGRKSVGAWLLSAH  220


>gi|254822596|ref|ZP_05227597.1| hypothetical protein MintA_21884 [Mycobacterium intracellulare 
ATCC 13950]
Length=222

 Score =  212 bits (539),  Expect = 4e-53, Method: Compositional matrix adjust.
 Identities = 124/228 (55%), Positives = 149/228 (66%), Gaps = 14/228 (6%)

Query  8    WDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            +++AYR +    G    PPW+IGEPQPE+A LI AGK   DVLDAGCG A +SL LA  G
Sbjct  2    FEAAYRGEAPEMGEGNRPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYLAERG  61

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            +T VG+D +PTA+  A + A  RGLT+ASF  ADI+ F  Y     GRF T++DSTLFHS
Sbjct  62   FTTVGLDQSPTAIELAREKAARRGLTSASFDVADISAFTGYD----GRFGTIVDSTLFHS  117

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            +PV+ RD Y  S+ RAAAPGASY+VLVF + A PA+  V  N V EDELR AVSKYW ID
Sbjct  118  MPVELRDGYQQSIVRAAAPGASYFVLVFDRAAMPADGPV--NAVTEDELRDAVSKYWVID  175

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYD-HDE-KGRVKFPAYLLTAH  230
            EIRPA IH N   +P         F   D  DE  GR    A+LL+AH
Sbjct  176  EIRPARIHAN---VPESFLEGFQAFAGADIRDEGNGRKSVGAWLLSAH  220


>gi|118465195|ref|YP_879415.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium 104]
 gi|118166482|gb|ABK67379.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium 104]
Length=231

 Score =  212 bits (539),  Expect = 4e-53, Method: Compositional matrix adjust.
 Identities = 120/228 (53%), Positives = 149/228 (66%), Gaps = 14/228 (6%)

Query  8    WDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            +++AYR +    G    PPW+IGEPQPE+A LI AGK   DVLDAGCG A +SL LA  G
Sbjct  11   FEAAYRGESPEMGEGARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYLAERG  70

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            +T VG+D +PTA+  A + A  RGLT+ASF  ADI++F  Y     GRF T++DSTLFHS
Sbjct  71   FTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYD----GRFGTIVDSTLFHS  126

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            +PV+ R+ Y  S+ +AAAPGASY+VLVF + A PAE  V  N V EDELR  V KYW ID
Sbjct  127  MPVELREGYQRSIVQAAAPGASYFVLVFDRNAMPAEGPV--NAVTEDELREVVGKYWVID  184

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYD--HDEKGRVKFPAYLLTAH  230
            EIRPA IH N   +P     A   F   D   ++ GR    A+LL+AH
Sbjct  185  EIRPARIHAN---VPENFLAAFEAFAGADIRDEDNGRKSVGAWLLSAH  229


>gi|254773164|ref|ZP_05214680.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium subsp. avium ATCC 25291]
Length=222

 Score =  211 bits (538),  Expect = 5e-53, Method: Compositional matrix adjust.
 Identities = 120/228 (53%), Positives = 149/228 (66%), Gaps = 14/228 (6%)

Query  8    WDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            +++AYR +    G    PPW+IGEPQPE+A LI AGK   DVLDAGCG A +SL LA  G
Sbjct  2    FEAAYRGESPEMGEGARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYLAERG  61

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            +T VG+D +PTA+  A + A  RGLT+ASF  ADI++F  Y     GRF T++DSTLFHS
Sbjct  62   FTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYD----GRFGTIVDSTLFHS  117

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            +PV+ R+ Y  S+ +AAAPGASY+VLVF + A PAE  V  N V EDELR  V KYW ID
Sbjct  118  MPVELREGYQRSIVQAAAPGASYFVLVFDRNAMPAEGPV--NAVTEDELREVVGKYWVID  175

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYD--HDEKGRVKFPAYLLTAH  230
            EIRPA IH N   +P     A   F   D   ++ GR    A+LL+AH
Sbjct  176  EIRPARIHAN---VPENFLAAFEAFAGADIRDEDNGRKSVGAWLLSAH  220


>gi|308231588|ref|ZP_07413001.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu001]
 gi|308369432|ref|ZP_07417752.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu002]
 gi|308370447|ref|ZP_07421523.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu003]
 22 more sequence titles
 
gi|308371706|ref|ZP_07425893.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu004]
 gi|308372931|ref|ZP_07430423.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu005]
 gi|308374042|ref|ZP_07434610.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu006]
 gi|308375194|ref|ZP_07443044.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu007]
 gi|308376441|ref|ZP_07438834.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu008]
 gi|308377459|ref|ZP_07479236.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu009]
 gi|308378671|ref|ZP_07483429.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu010]
 gi|308379813|ref|ZP_07487662.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu011]
 gi|308395844|ref|ZP_07492167.2| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu012]
 gi|308216770|gb|EFO76169.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu001]
 gi|308327629|gb|EFP16480.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu002]
 gi|308331984|gb|EFP20835.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu003]
 gi|308335771|gb|EFP24622.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu004]
 gi|308339377|gb|EFP28228.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu005]
 gi|308343253|gb|EFP32104.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu006]
 gi|308347145|gb|EFP35996.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu007]
 gi|308351083|gb|EFP39934.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu008]
 gi|308355719|gb|EFP44570.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu009]
 gi|308359674|gb|EFP48525.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu010]
 gi|308363579|gb|EFP52430.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu011]
 gi|308367215|gb|EFP56066.1| benzoquinone methyltransferase [Mycobacterium tuberculosis SUMu012]
 gi|323721034|gb|EGB30098.1| benzoquinone methyltransferase [Mycobacterium tuberculosis CDC1551A]
Length=225

 Score =  210 bits (534),  Expect = 1e-52, Method: Compositional matrix adjust.
 Identities = 125/234 (54%), Positives = 152/234 (65%), Gaps = 15/234 (6%)

Query  1    MTDEV-MDWDSAYR-EQGAF-EG-PPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAEL  56
            MT+ + ++++SAYR E  AF EG  PPW+IGEPQPELA LI  GK R DVLD GCG A +
Sbjct  1    MTESLDLEFESAYRGESVAFGEGVRPPWSIGEPQPELAALIVQGKFRGDVLDVGCGEAAI  60

Query  57   SLALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTV  116
            SLALA  G+T VG+DL+P AV  A   A +RGL  ASF  AD + F  Y     GRF T+
Sbjct  61   SLALAERGHTTVGLDLSPAAVELARHEAAKRGLANASFEVADASSFTGYD----GRFDTI  116

Query  117  IDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAA  176
            +DSTLFHS+PV+SR+ YL S+ RAAAPGASY+VLVF + A P   E   N V EDELRAA
Sbjct  117  VDSTLFHSMPVESREGYLQSIVRAAAPGASYFVLVFDRAAIP---EGPINAVTEDELRAA  173

Query  177  VSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAH  230
            VSKYW IDEI+PA ++      P   AG P        +  G      +LL+AH
Sbjct  174  VSKYWIIDEIKPARLYAR---FPAGFAGMPA-LLDIREEPNGLQSIGGWLLSAH  223


>gi|15607700|ref|NP_215074.1| benzoquinone methyltransferase [Mycobacterium tuberculosis H37Rv]
 gi|15839958|ref|NP_334995.1| hypothetical protein MT0586 [Mycobacterium tuberculosis CDC1551]
 gi|31791742|ref|NP_854235.1| benzoquinone methyltransferase [Mycobacterium bovis AF2122/97]
 49 more sequence titles
 
gi|121636478|ref|YP_976701.1| putative benzoquinone methyltransferase [Mycobacterium bovis 
BCG str. Pasteur 1173P2]
 gi|148660329|ref|YP_001281852.1| putative benzoquinone methyltransferase [Mycobacterium tuberculosis 
H37Ra]
 gi|148821761|ref|YP_001286515.1| benzoquinone methyltransferase [Mycobacterium tuberculosis F11]
 gi|167968367|ref|ZP_02550644.1| hypothetical benzoquinone methyltransferase [Mycobacterium tuberculosis 
H37Ra]
 gi|224988950|ref|YP_002643637.1| putative benzoquinone methyltransferase [Mycobacterium bovis 
BCG str. Tokyo 172]
 gi|253797492|ref|YP_003030493.1| benzoquinone methyltransferase [Mycobacterium tuberculosis KZN 
1435]
 gi|254230903|ref|ZP_04924230.1| hypothetical protein TBCG_00555 [Mycobacterium tuberculosis C]
 gi|254363519|ref|ZP_04979565.1| hypothetical benzoquinone methyltransferase [Mycobacterium tuberculosis 
str. Haarlem]
 gi|254549515|ref|ZP_05139962.1| benzoquinone methyltransferase [Mycobacterium tuberculosis '98-R604 
INH-RIF-EM']
 gi|289441945|ref|ZP_06431689.1| benzoquinone methyltransferase [Mycobacterium tuberculosis T46]
 gi|289446107|ref|ZP_06435851.1| benzoquinone methyltransferase [Mycobacterium tuberculosis CPHL_A]
 gi|289552812|ref|ZP_06442022.1| benzoquinone methyltransferase [Mycobacterium tuberculosis KZN 
605]
 gi|289568488|ref|ZP_06448715.1| benzoquinone methyltransferase [Mycobacterium tuberculosis T17]
 gi|289573152|ref|ZP_06453379.1| benzoquinone methyltransferase [Mycobacterium tuberculosis K85]
 gi|289744273|ref|ZP_06503651.1| benzoquinone methyltransferase [Mycobacterium tuberculosis 02_1987]
 gi|289749059|ref|ZP_06508437.1| benzoquinone methyltransferase [Mycobacterium tuberculosis T92]
 gi|289752599|ref|ZP_06511977.1| benzoquinone methyltransferase [Mycobacterium tuberculosis EAS054]
 gi|289756637|ref|ZP_06516015.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|289760679|ref|ZP_06520057.1| benzoquinone methyltransferase [Mycobacterium tuberculosis GM 
1503]
 gi|294996070|ref|ZP_06801761.1| benzoquinone methyltransferase [Mycobacterium tuberculosis 210]
 gi|297633050|ref|ZP_06950830.1| benzoquinone methyltransferase [Mycobacterium tuberculosis KZN 
4207]
 gi|297730027|ref|ZP_06959145.1| benzoquinone methyltransferase [Mycobacterium tuberculosis KZN 
R506]
 gi|313657355|ref|ZP_07814235.1| benzoquinone methyltransferase [Mycobacterium tuberculosis KZN 
V2475]
 gi|339630630|ref|YP_004722272.1| benzoquinone methyltransferase [Mycobacterium africanum GM041182]
 gi|2114022|emb|CAB08971.1| POSSIBLE BENZOQUINONE METHYLTRANSFERASE (METHYLASE) [Mycobacterium 
tuberculosis H37Rv]
 gi|13880098|gb|AAK44809.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
 gi|31617328|emb|CAD93437.1| POSSIBLE BENZOQUINONE METHYLTRANSFERASE (METHYLASE) [Mycobacterium 
bovis AF2122/97]
 gi|121492125|emb|CAL70590.1| POssible benzoquinone methyltransferase [Mycobacterium bovis 
BCG str. Pasteur 1173P2]
 gi|124599962|gb|EAY58972.1| hypothetical protein TBCG_00555 [Mycobacterium tuberculosis C]
 gi|134149033|gb|EBA41078.1| hypothetical benzoquinone methyltransferase [Mycobacterium tuberculosis 
str. Haarlem]
 gi|148504481|gb|ABQ72290.1| putative benzoquinone methyltransferase [Mycobacterium tuberculosis 
H37Ra]
 gi|148720288|gb|ABR04913.1| hypothetical benzoquinone methyltransferase [Mycobacterium tuberculosis 
F11]
 gi|224772063|dbj|BAH24869.1| putative benzoquinone methyltransferase [Mycobacterium bovis 
BCG str. Tokyo 172]
 gi|253318995|gb|ACT23598.1| benzoquinone methyltransferase [Mycobacterium tuberculosis KZN 
1435]
 gi|289414864|gb|EFD12104.1| benzoquinone methyltransferase [Mycobacterium tuberculosis T46]
 gi|289419065|gb|EFD16266.1| benzoquinone methyltransferase [Mycobacterium tuberculosis CPHL_A]
 gi|289437444|gb|EFD19937.1| benzoquinone methyltransferase [Mycobacterium tuberculosis KZN 
605]
 gi|289537583|gb|EFD42161.1| benzoquinone methyltransferase [Mycobacterium tuberculosis K85]
 gi|289542242|gb|EFD45890.1| benzoquinone methyltransferase [Mycobacterium tuberculosis T17]
 gi|289684801|gb|EFD52289.1| benzoquinone methyltransferase [Mycobacterium tuberculosis 02_1987]
 gi|289689646|gb|EFD57075.1| benzoquinone methyltransferase [Mycobacterium tuberculosis T92]
 gi|289693186|gb|EFD60615.1| benzoquinone methyltransferase [Mycobacterium tuberculosis EAS054]
 gi|289708185|gb|EFD72201.1| benzoquinone methyltransferase [Mycobacterium tuberculosis GM 
1503]
 gi|289712201|gb|EFD76213.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|326902389|gb|EGE49322.1| benzoquinone methyltransferase [Mycobacterium tuberculosis W-148]
 gi|328457277|gb|AEB02700.1| benzoquinone methyltransferase [Mycobacterium tuberculosis KZN 
4207]
 gi|339329986|emb|CCC25639.1| putative benzoquinone methyltransferase (methylase) [Mycobacterium 
africanum GM041182]
 gi|341600494|emb|CCC63164.1| possible benzoquinone methyltransferase [Mycobacterium bovis 
BCG str. Moreau RDJ]
 gi|344218381|gb|AEM99011.1| benzoquinone methyltransferase [Mycobacterium tuberculosis CTRI-2]
Length=241

 Score =  210 bits (534),  Expect = 2e-52, Method: Compositional matrix adjust.
 Identities = 125/234 (54%), Positives = 152/234 (65%), Gaps = 15/234 (6%)

Query  1    MTDEV-MDWDSAYR-EQGAF-EG-PPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAEL  56
            MT+ + ++++SAYR E  AF EG  PPW+IGEPQPELA LI  GK R DVLD GCG A +
Sbjct  17   MTESLDLEFESAYRGESVAFGEGVRPPWSIGEPQPELAALIVQGKFRGDVLDVGCGEAAI  76

Query  57   SLALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTV  116
            SLALA  G+T VG+DL+P AV  A   A +RGL  ASF  AD + F  Y     GRF T+
Sbjct  77   SLALAERGHTTVGLDLSPAAVELARHEAAKRGLANASFEVADASSFTGYD----GRFDTI  132

Query  117  IDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAA  176
            +DSTLFHS+PV+SR+ YL S+ RAAAPGASY+VLVF + A P   E   N V EDELRAA
Sbjct  133  VDSTLFHSMPVESREGYLQSIVRAAAPGASYFVLVFDRAAIP---EGPINAVTEDELRAA  189

Query  177  VSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAH  230
            VSKYW IDEI+PA ++      P   AG P        +  G      +LL+AH
Sbjct  190  VSKYWIIDEIKPARLYAR---FPAGFAGMPA-LLDIREEPNGLQSIGGWLLSAH  239


>gi|298524048|ref|ZP_07011457.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298493842|gb|EFI29136.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|339293605|gb|AEJ45716.1| benzoquinone methyltransferase [Mycobacterium tuberculosis CCDC5079]
 gi|339297245|gb|AEJ49355.1| benzoquinone methyltransferase [Mycobacterium tuberculosis CCDC5180]
Length=238

 Score =  209 bits (533),  Expect = 2e-52, Method: Compositional matrix adjust.
 Identities = 125/234 (54%), Positives = 152/234 (65%), Gaps = 15/234 (6%)

Query  1    MTDEV-MDWDSAYR-EQGAF-EG-PPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAEL  56
            MT+ + ++++SAYR E  AF EG  PPW+IGEPQPELA LI  GK R DVLD GCG A +
Sbjct  14   MTESLDLEFESAYRGESVAFGEGVRPPWSIGEPQPELAALIVQGKFRGDVLDVGCGEAAI  73

Query  57   SLALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTV  116
            SLALA  G+T VG+DL+P AV  A   A +RGL  ASF  AD + F  Y     GRF T+
Sbjct  74   SLALAERGHTTVGLDLSPAAVELARHEAAKRGLANASFEVADASSFTGYD----GRFDTI  129

Query  117  IDSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAA  176
            +DSTLFHS+PV+SR+ YL S+ RAAAPGASY+VLVF + A P   E   N V EDELRAA
Sbjct  130  VDSTLFHSMPVESREGYLQSIVRAAAPGASYFVLVFDRAAIP---EGPINAVTEDELRAA  186

Query  177  VSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAH  230
            VSKYW IDEI+PA ++      P   AG P        +  G      +LL+AH
Sbjct  187  VSKYWIIDEIKPARLYAR---FPAGFAGMPA-LLDIREEPNGLQSIGGWLLSAH  236


>gi|296167043|ref|ZP_06849455.1| thiopurine S-methyltransferase family protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295897600|gb|EFG77194.1| thiopurine S-methyltransferase family protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=222

 Score =  207 bits (526),  Expect = 1e-51, Method: Compositional matrix adjust.
 Identities = 121/228 (54%), Positives = 145/228 (64%), Gaps = 14/228 (6%)

Query  8    WDSAYREQGAFEGP---PPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            ++SAYR +    G    PPW+IGEPQPE+A LI AGK   DVLDAGCG A +SL LA  G
Sbjct  2    FESAYRGEAPEMGEGNRPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLFLAERG  61

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            +T VG+D +PTA+  AT+ A  RGL  A+F  ADI+ F  Y     GRF T++DSTLFHS
Sbjct  62   FTTVGLDQSPTAIKLATEKAARRGLANATFDVADISAFGGYD----GRFGTIVDSTLFHS  117

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            +PV+ R+ Y  S+ RAAAPGASY+VLVF +   PA   V  N V EDELR  VSKYW ID
Sbjct  118  MPVELREGYQQSIVRAAAPGASYFVLVFDRAGMPAGGPV--NAVTEDELRDVVSKYWVID  175

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYD-HDE-KGRVKFPAYLLTAH  230
            EIRPA IH N   +P         F   D  DE  GR    A+LL+AH
Sbjct  176  EIRPARIHAN---VPDSALEGFQAFSGADIRDEGNGRKSIGAWLLSAH  220


>gi|333989194|ref|YP_004521808.1| methyltransferase [Mycobacterium sp. JDM601]
 gi|333485162|gb|AEF34554.1| methyltransferase [Mycobacterium sp. JDM601]
Length=220

 Score =  204 bits (519),  Expect = 9e-51, Method: Compositional matrix adjust.
 Identities = 115/228 (51%), Positives = 142/228 (63%), Gaps = 15/228 (6%)

Query  6    MDWDSAYR---EQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAA  62
              +D+AYR   EQ      PPW+IGEPQPELA LI  GK   D+LD GCG A +SL +A 
Sbjct  3    FQFDAAYRGESEQMGLGAKPPWSIGEPQPELAALIEQGKFHGDILDVGCGEAAISLHMAE  62

Query  63   DGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLF  122
             G+T VG+DL+ TA+  A   A +RGLT A+F  ADI+ F  Y     GRF T++DSTLF
Sbjct  63   RGHTTVGLDLSSTAIDLARAEAAKRGLTNATFEVADISNFTGYD----GRFGTIVDSTLF  118

Query  123  HSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWK  182
            HS+PV++RD Y  S+ RAAAPGASY+VLVF K A PA     P  V +DELR  VSKYW 
Sbjct  119  HSIPVEARDGYQRSIVRAAAPGASYFVLVFDKAAIPAG---PPFAVTDDELRDIVSKYWV  175

Query  183  IDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAH  230
            IDEI+PA +H       P   G P++  P      GR     +LL+AH
Sbjct  176  IDEIKPARLHAVFPDDFPGFGGVPLQDEP-----GGRKSAAGWLLSAH  218


>gi|169629918|ref|YP_001703567.1| hypothetical protein MAB_2834c [Mycobacterium abscessus ATCC 
19977]
 gi|169241885|emb|CAM62913.1| Conserved hypothetical protein (methyltransferase?) [Mycobacterium 
abscessus]
Length=227

 Score =  196 bits (499),  Expect = 2e-48, Method: Compositional matrix adjust.
 Identities = 110/234 (48%), Positives = 143/234 (62%), Gaps = 11/234 (4%)

Query  1    MTDEVMD-WDSAYREQG--AFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELS  57
            MT+ + D ++S+YR +        PPW+IG+PQPE+  LI  GKV  DVLDAGCG A  +
Sbjct  1    MTENLQDMFESSYRGEAPEQLAARPPWSIGQPQPEILKLIEQGKVHGDVLDAGCGEAATA  60

Query  58   LALAADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVI  117
            L LA  G+T VG+D  PTA+  A   A ERGLT  +F  ADI+ F  Y     GRF T+I
Sbjct  61   LYLAERGHTAVGLDAAPTAIQLAKGYAAERGLTNVTFDVADISNFTGYD----GRFGTII  116

Query  118  DSTLFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAV  177
            DSTLFHS+PV+ R+ Y  S+ RAAAPGA+Y VLVF K AFP +++  P+ V E ELR  V
Sbjct  117  DSTLFHSMPVELREGYQQSIVRAAAPGANYIVLVFDKAAFPPDID-GPHPVSEPELREIV  175

Query  178  SKYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHK  231
            SKYW +D+I PA ++ N         G    F  +  +  G V    +LL AH+
Sbjct  176  SKYWTVDDISPARLYANGDGFQD---GGAQRFAEFREESNGWVSMAGWLLQAHR  226


>gi|118470628|ref|YP_886876.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
smegmatis str. MC2 155]
 gi|118171915|gb|ABK72811.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
smegmatis str. MC2 155]
Length=226

 Score =  185 bits (470),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 114/234 (49%), Positives = 138/234 (59%), Gaps = 28/234 (11%)

Query  8    WDSAYR-EQGAFEG-PPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADGY  65
            ++SAYR E   F G  PPW+IGEPQPE+  LI AGK   +VLDAGCG A  +L LAA G+
Sbjct  8    FESAYRGEAPNFGGVRPPWSIGEPQPEIRKLIDAGKFHGEVLDAGCGEAATALYLAAQGF  67

Query  66   TVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSL  125
            T VG+D +PTA+  A   A  RGLT A+F  ADI+ F  Y     GRF T++DSTLFHS+
Sbjct  68   TTVGLDQSPTAIELARAEAARRGLTNATFEVADISSFTGYD----GRFGTIVDSTLFHSM  123

Query  126  PVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKP-NEVDEDELRAAVSKYWKID  184
            PV+ RD Y  S+ RAAAPGA+Y VLVF K       +  P N V +DELR  V +YW ID
Sbjct  124  PVELRDGYQQSIVRAAAPGATYVVLVFDKTTMG---DTGPANPVTDDELRDVVGRYWVID  180

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYD-------HDE-KGRVKFPAYLLTAH  230
            +I PA IH N           P EF  +         DE  GR     +LL AH
Sbjct  181  DISPARIHAN----------VPAEFTDFAAFAGSDIRDEGNGRKSVAGWLLQAH  224


>gi|342860008|ref|ZP_08716660.1| hypothetical protein MCOL_14050 [Mycobacterium colombiense CECT 
3035]
 gi|342132386|gb|EGT85615.1| hypothetical protein MCOL_14050 [Mycobacterium colombiense CECT 
3035]
Length=223

 Score =  183 bits (464),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 115/234 (50%), Positives = 149/234 (64%), Gaps = 16/234 (6%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT+   DWD+AYR+      PPPW+IG PQPELA LI  GK+R +VLD+GCG+A LSL L
Sbjct  1    MTEPDRDWDAAYRQ----ADPPPWSIGRPQPELALLIDQGKIRGEVLDSGCGHAALSLTL  56

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA GYTVVG+D + TA+ AA  AA  RGLTTASF QAD+T+F  Y     GRF T++DS 
Sbjct  57   AALGYTVVGLDASATAIEAARAAAAGRGLTTASFAQADVTDFGGYD----GRFGTILDSG  112

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPN--EVDEDELRAAVS  178
            LFH+LP D R  YL S+ RAAAPGA+ Y+L FA GA       +P      + EL  AV+
Sbjct  113  LFHALPPDRRQAYLWSIFRAAAPGAALYILAFAAGALDDAHSDRPGPPGFTQTELHDAVA  172

Query  179  KYWKIDEIRPAFIHVNPVTIPPQLAGAP-VEFPPYDHDEKGRVKFPAYLLTAHK  231
              W++D++R A ++          AG+P       +HD++G    P +LL+AHK
Sbjct  173  ALWQVDDVRQAKVYGT-----DDAAGSPDGPLAHLEHDDEGHFMAPGFLLSAHK  221


>gi|254822456|ref|ZP_05227457.1| hypothetical protein MintA_21156 [Mycobacterium intracellulare 
ATCC 13950]
Length=220

 Score =  181 bits (458),  Expect = 1e-43, Method: Compositional matrix adjust.
 Identities = 118/235 (51%), Positives = 149/235 (64%), Gaps = 17/235 (7%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT    DWD+AYR+      PPPW+IG PQPELA LI  G VRS+VLD+GCG+A LSLAL
Sbjct  1    MTQPDRDWDAAYRQ----AAPPPWSIGRPQPELARLIDQGLVRSEVLDSGCGHAALSLAL  56

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA GYTVVG+D + TAV AA  AA E+GL+TASF QAD+T F  Y     GRFST++DS 
Sbjct  57   AARGYTVVGLDASATAVQAAAAAAAEQGLSTASFAQADVTTFRGYD----GRFSTILDSG  112

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPN--EVDEDELRAAVS  178
            LFH+L  + R  Y+ S+ RAAAPGA+ Y+L FA GA       +P      E EL  AVS
Sbjct  113  LFHALAPERRQDYVQSIFRAAAPGAALYILAFAAGALDQAHPDRPGPPGFTETELHDAVS  172

Query  179  KYWKIDEIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKAG  233
              W++D+IR A ++    +    LA         +HD++G    P +LL+AHK G
Sbjct  173  TLWRVDDIRVAKVYGKDESSDGSLA-------HLEHDDEGHFMAPGFLLSAHKPG  220


>gi|289571942|ref|ZP_06452169.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289545696|gb|EFD49344.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
Length=85

 Score =  173 bits (438),  Expect = 2e-41, Method: Compositional matrix adjust.
 Identities = 83/85 (98%), Positives = 85/85 (100%), Gaps = 0/85 (0%)

Query  149  VLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVE  208
            +LVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVE
Sbjct  1    MLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKIDEIRPAFIHVNPVTIPPQLAGAPVE  60

Query  209  FPPYDHDEKGRVKFPAYLLTAHKAG  233
            FPPYDHD+KGRVKFPAYLLTAHKAG
Sbjct  61   FPPYDHDKKGRVKFPAYLLTAHKAG  85


>gi|41406366|ref|NP_959202.1| hypothetical protein MAP0268c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41394714|gb|AAS02585.1| hypothetical protein MAP_0268c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336460758|gb|EGO39646.1| Thiopurine S-methyltransferase (TPMT) [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=227

 Score =  168 bits (425),  Expect = 7e-40, Method: Compositional matrix adjust.
 Identities = 120/234 (52%), Positives = 152/234 (65%), Gaps = 12/234 (5%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT    DWD+AYR+      PPPW+IG PQPEL  LI  GK RSDVLD+GCG+A LSL L
Sbjct  1    MTQPDTDWDAAYRQAA----PPPWSIGRPQPELERLIDEGKFRSDVLDSGCGHAALSLRL  56

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA G+TVVG+D + TA+A AT AA  +GLTTA+F +AD+T+FA YP GS GRF+T++DS 
Sbjct  57   AALGHTVVGLDASATAIAEATAAAAAQGLTTATFARADVTDFADYPPGSEGRFATIVDSG  116

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVK--PNEVDEDELRAAVS  178
            LFH+LP   R  YL S+ RAAAPGA+ Y+L FA GA       +  P    E ELR AVS
Sbjct  117  LFHALPPQRRQDYLRSIFRAAAPGAALYILAFAAGALAPAHPDRPGPQGFTETELREAVS  176

Query  179  KYWKIDEIRPAFIHVNPVTIPPQLAGAPVE-FPPYDHDEKGRVKFPAYLLTAHK  231
              W ID++  A ++ N  +     AGAP       +HD +G    P +L++AHK
Sbjct  177  VLWHIDDLHAARVYGNDDS-----AGAPDSPLAHLEHDGEGHFMAPGFLVSAHK  225


>gi|118467221|ref|YP_879601.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium 104]
 gi|118168508|gb|ABK69405.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium 104]
Length=227

 Score =  167 bits (422),  Expect = 1e-39, Method: Compositional matrix adjust.
 Identities = 120/234 (52%), Positives = 152/234 (65%), Gaps = 12/234 (5%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT    DWD+AYR+      PPPW+IG PQPEL  LI  GK RSDVLD+GCG+A LSL L
Sbjct  1    MTQPDTDWDAAYRQAA----PPPWSIGRPQPELERLIDEGKFRSDVLDSGCGHAALSLRL  56

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA G+TVVG+D + TA+A AT AA  +GLTTA+F +AD+T+FA YP GS GRF+T++DS 
Sbjct  57   AALGHTVVGLDASATAIAEATAAAAAQGLTTATFARADVTDFADYPPGSEGRFATIVDSG  116

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVK--PNEVDEDELRAAVS  178
            LFH+LP   R  YL S+ RAAAPGA+ Y+L FA GA       +  P    E ELR AVS
Sbjct  117  LFHALPPQRRQDYLRSIFRAAAPGAALYILAFAAGALAPAHPDRPGPQGFTETELREAVS  176

Query  179  KYWKIDEIRPAFIHVNPVTIPPQLAGAPVE-FPPYDHDEKGRVKFPAYLLTAHK  231
              W ID++R A ++ N  +     AGAP       + D +G    P +L++AHK
Sbjct  177  VLWHIDDLRAARVYGNDDS-----AGAPDSPLAHLERDGEGHFMAPGFLVSAHK  225


>gi|254773323|ref|ZP_05214839.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium subsp. avium ATCC 25291]
Length=227

 Score =  163 bits (412),  Expect = 2e-38, Method: Compositional matrix adjust.
 Identities = 119/234 (51%), Positives = 151/234 (65%), Gaps = 12/234 (5%)

Query  1    MTDEVMDWDSAYREQGAFEGPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLAL  60
            MT    DWD+A R+      PPPW+IG PQPEL  LI  GK RSDVLD+GCG+A LSL L
Sbjct  1    MTQPDTDWDAADRQAA----PPPWSIGRPQPELERLIDEGKFRSDVLDSGCGHAALSLRL  56

Query  61   AADGYTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDST  120
            AA G+TVVG+D + TA+A AT AA  +GLTTA+F +AD+T+FA YP GS GRF+T++DS 
Sbjct  57   AALGHTVVGLDASATAIAEATAAAAAQGLTTATFARADVTDFADYPPGSEGRFATIVDSG  116

Query  121  LFHSLPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVK--PNEVDEDELRAAVS  178
            LFH+LP   R  YL S+ RAAAPGA+ Y+L FA GA       +  P    E ELR AVS
Sbjct  117  LFHALPPQRRQDYLRSIFRAAAPGAALYILAFAAGALAPAHPDRPGPQGFTETELREAVS  176

Query  179  KYWKIDEIRPAFIHVNPVTIPPQLAGAPVE-FPPYDHDEKGRVKFPAYLLTAHK  231
              W ID++R A ++ N  +     AGAP       + D +G    P +L++AHK
Sbjct  177  VLWHIDDLRAARVYGNDDS-----AGAPDSPLAHLERDGEGHFMAPGFLVSAHK  225


>gi|169631872|ref|YP_001705521.1| hypothetical protein MAB_4799c [Mycobacterium abscessus ATCC 
19977]
 gi|169243839|emb|CAM64867.1| Conserved hypothetical protein (methyltransferase?) [Mycobacterium 
abscessus]
Length=219

 Score =  161 bits (408),  Expect = 7e-38, Method: Compositional matrix adjust.
 Identities = 96/228 (43%), Positives = 124/228 (55%), Gaps = 10/228 (4%)

Query  6    MDWDSAYREQGAFE-GPPPWNIGEPQPELATLIAAGKVRSDVLDAGCGYAELSLALAADG  64
            MDWD  YR +  +  G P WNIGE QPELA L   G+  S +LDAGCG    SLALA  G
Sbjct  1    MDWDELYRGEAVYAPGDPGWNIGEMQPELAALHRQGRFESPILDAGCGIGSTSLALAGHG  60

Query  65   YTVVGIDLTPTAVAAATKAAEERGLTTASFVQADITEFAAYPAGSAGRFSTVIDSTLFHS  124
            Y VVG+DL+  A+  A KAAE   L    F  AD+T    Y       F+TVID  +FH 
Sbjct  61   YQVVGLDLSSGAIEKAKKAAEPLALDVV-FDTADLTSDIGY----NDHFNTVIDGLVFHC  115

Query  125  LPVDSRDRYLSSVHRAAAPGASYYVLVFAKGAFPAELEVKPNEVDEDELRAAVSKYWKID  184
            LP   R  Y+ S+ R+  PG  ++ LVFA  AFP   E  P    E +LR  V ++  +D
Sbjct  116  LPAQIRGDYVRSLARSLKPGGRFFALVFATEAFPPNAEFGPRPFTEQQLRDIVGRHLVVD  175

Query  185  EIRPAFIHVNPVTIPPQLAGAPVEFPPYDHDEKGRVKFPAYLLTAHKA  232
            E+R A   VN   +P QL     E+        GR + PA+L++AH++
Sbjct  176  EVRRARAWVN---VPGQLPEG-FEYRNVTIGSDGRAQLPAWLVSAHRS  219



Lambda     K      H
   0.316    0.133    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 310059402884


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40