BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3764c Length=475 Score E Sequences producing significant alignments: (Bits) Value gi|15610900|ref|NP_218281.1| two component sensor kinase [Mycoba... 942 0.0 gi|167970925|ref|ZP_02553202.1| two component sensor kinase [Myc... 942 0.0 gi|289556029|ref|ZP_06445239.1| two component system sensor kina... 937 0.0 gi|254366309|ref|ZP_04982353.1| hypothetical two component senso... 937 0.0 gi|254552878|ref|ZP_05143325.1| two component system sensor kina... 936 0.0 gi|15843384|ref|NP_338421.1| sensor histidine kinase [Mycobacter... 936 0.0 gi|31794934|ref|NP_857427.1| putative two component sensor kinas... 933 0.0 gi|289445363|ref|ZP_06435107.1| two component system sensor kina... 931 0.0 gi|340628735|ref|YP_004747187.1| putative two component sensor k... 918 0.0 gi|342860016|ref|ZP_08716668.1| sensor histidine kinase [Mycobac... 758 0.0 gi|183985284|ref|YP_001853575.1| two-component sensor kinase Tcr... 747 0.0 gi|296166888|ref|ZP_06849305.1| sensor histidine kinase [Mycobac... 745 0.0 gi|118466581|ref|YP_879594.1| sensor histidine kinase [Mycobacte... 741 0.0 gi|41406358|ref|NP_959194.1| hypothetical protein MAP0260 [Mycob... 740 0.0 gi|336460749|gb|EGO39637.1| signal transduction histidine kinase... 739 0.0 gi|254773314|ref|ZP_05214830.1| sensor histidine kinase [Mycobac... 738 0.0 gi|240168528|ref|ZP_04747187.1| hypothetical protein MkanA1_0439... 733 0.0 gi|254822465|ref|ZP_05227466.1| sensor histidine kinase [Mycobac... 728 0.0 gi|333992681|ref|YP_004525295.1| two-component sensor kinase Tcr... 547 2e-153 gi|119870029|ref|YP_939981.1| integral membrane sensor signal tr... 520 2e-145 gi|108800889|ref|YP_641086.1| periplasmic sensor signal transduc... 519 4e-145 gi|126436515|ref|YP_001072206.1| integral membrane sensor signal... 517 1e-144 gi|120405381|ref|YP_955210.1| integral membrane sensor signal tr... 488 1e-135 gi|145222855|ref|YP_001133533.1| integral membrane sensor signal... 469 5e-130 gi|118470188|ref|YP_889240.1| sensor histidine kinase [Mycobacte... 461 2e-127 gi|296394074|ref|YP_003658958.1| integral membrane sensor signal... 438 1e-120 gi|169629668|ref|YP_001703317.1| putative two component sensor k... 419 5e-115 gi|159037875|ref|YP_001537128.1| histidine kinase [Salinispora a... 411 2e-112 gi|302530943|ref|ZP_07283285.1| histidine kinase [Streptomyces s... 406 5e-111 gi|111220169|ref|YP_710963.1| putative sensor histidine kinase [... 399 4e-109 gi|312200459|ref|YP_004020520.1| integral membrane sensor signal... 399 5e-109 gi|145594663|ref|YP_001158960.1| ATPase domain-containing protei... 399 6e-109 gi|302528955|ref|ZP_07281297.1| phosphate regulon sensor kinase ... 394 1e-107 gi|50954149|ref|YP_061437.1| two-component system, sensor protei... 391 1e-106 gi|86739036|ref|YP_479436.1| periplasmic sensor signal transduct... 389 7e-106 gi|302867312|ref|YP_003835949.1| ATP-binding region ATPase domai... 389 8e-106 gi|300788582|ref|YP_003768873.1| two-component system histidine ... 387 2e-105 gi|88856022|ref|ZP_01130684.1| two-component system, sensor prot... 387 2e-105 gi|258654799|ref|YP_003203955.1| histidine kinase [Nakamurella m... 383 3e-104 gi|170780990|ref|YP_001709322.1| putative two component sensor k... 375 1e-101 gi|158318232|ref|YP_001510740.1| integral membrane sensor signal... 374 2e-101 gi|256375857|ref|YP_003099517.1| histidine kinase [Actinosynnema... 373 3e-101 gi|148273949|ref|YP_001223510.1| putative two-component system, ... 361 2e-97 gi|328883820|emb|CCA57059.1| Two-component system, sensor protei... 360 2e-97 gi|152966981|ref|YP_001362765.1| integral membrane sensor signal... 360 3e-97 gi|297158649|gb|ADI08361.1| putative two component system sensor... 359 5e-97 gi|288918082|ref|ZP_06412439.1| histidine kinase [Frankia sp. EU... 359 7e-97 gi|336116251|ref|YP_004571017.1| two-component system histidine ... 358 9e-97 gi|119962003|ref|YP_946601.1| signal transduction histidine kina... 357 2e-96 gi|317126454|ref|YP_004100566.1| integral membrane sensor signal... 357 2e-96 >gi|15610900|ref|NP_218281.1| two component sensor kinase [Mycobacterium tuberculosis H37Rv] gi|148663630|ref|YP_001285153.1| two component sensor kinase [Mycobacterium tuberculosis H37Ra] gi|81556462|sp|O69729.1|TCRY_MYCTU RecName: Full=Probable sensor histidine kinase TcrY gi|2960188|emb|CAA18086.1| POSSIBLE TWO COMPONENT SENSOR KINASE [Mycobacterium tuberculosis H37Rv] gi|148507782|gb|ABQ75591.1| two component sensor kinase [Mycobacterium tuberculosis H37Ra] Length=475 Score = 942 bits (2435), Expect = 0.0, Method: Compositional matrix adjust. Identities = 474/475 (99%), Positives = 475/475 (100%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL Sbjct 1 MGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG Sbjct 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA Sbjct 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR Sbjct 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 >gi|167970925|ref|ZP_02553202.1| two component sensor kinase [Mycobacterium tuberculosis H37Ra] gi|308232560|ref|ZP_07664115.1| two component system sensor kinase [Mycobacterium tuberculosis SUMu001] gi|308379611|ref|ZP_07669000.1| two component system sensor kinase [Mycobacterium tuberculosis SUMu010] 6 more sequence titles Length=506 Score = 942 bits (2435), Expect = 0.0, Method: Compositional matrix adjust. Identities = 475/475 (100%), Positives = 475/475 (100%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL Sbjct 32 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 91 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG Sbjct 92 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 151 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA Sbjct 152 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 211 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 212 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 271 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 272 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 331 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 332 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 391 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 392 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 451 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR Sbjct 452 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 506 >gi|289556029|ref|ZP_06445239.1| two component system sensor kinase [Mycobacterium tuberculosis KZN 605] gi|289440661|gb|EFD23154.1| two component system sensor kinase [Mycobacterium tuberculosis KZN 605] Length=490 Score = 937 bits (2423), Expect = 0.0, Method: Compositional matrix adjust. Identities = 474/475 (99%), Positives = 474/475 (99%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL Sbjct 16 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 75 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG Sbjct 76 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 135 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA Sbjct 136 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 195 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 196 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 255 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 256 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 315 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 316 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 375 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 376 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 435 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR Sbjct 436 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 490 >gi|254366309|ref|ZP_04982353.1| hypothetical two component sensor kinase [Mycobacterium tuberculosis str. Haarlem] gi|298527237|ref|ZP_07014646.1| sensor histidine kinase [Mycobacterium tuberculosis 94_M4241A] gi|134151821|gb|EBA43866.1| hypothetical two component sensor kinase [Mycobacterium tuberculosis str. Haarlem] gi|298497031|gb|EFI32325.1| sensor histidine kinase [Mycobacterium tuberculosis 94_M4241A] gi|323717629|gb|EGB26831.1| two component system sensor kinase [Mycobacterium tuberculosis CDC1551A] gi|339296571|gb|AEJ48682.1| two component sensor kinase [Mycobacterium tuberculosis CCDC5079] gi|339300170|gb|AEJ52280.1| two component sensor kinase [Mycobacterium tuberculosis CCDC5180] Length=478 Score = 937 bits (2421), Expect = 0.0, Method: Compositional matrix adjust. Identities = 474/475 (99%), Positives = 474/475 (99%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL Sbjct 4 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 63 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG Sbjct 64 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 123 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA Sbjct 124 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 183 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 184 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 243 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 244 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 303 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 304 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 363 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 364 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 423 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR Sbjct 424 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 478 >gi|254552878|ref|ZP_05143325.1| two component system sensor kinase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|289759926|ref|ZP_06519304.1| two component sensor kinase [Mycobacterium tuberculosis T85] gi|289763946|ref|ZP_06523324.1| two component sensor kinase [Mycobacterium tuberculosis GM 1503] 7 more sequence titles Length=475 Score = 936 bits (2420), Expect = 0.0, Method: Compositional matrix adjust. Identities = 473/475 (99%), Positives = 474/475 (99%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL Sbjct 1 MGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG Sbjct 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA Sbjct 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 241 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR Sbjct 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 >gi|15843384|ref|NP_338421.1| sensor histidine kinase [Mycobacterium tuberculosis CDC1551] gi|148824969|ref|YP_001289723.1| two component sensor kinase [Mycobacterium tuberculosis F11] gi|253800811|ref|YP_003033812.1| two component system sensor kinase [Mycobacterium tuberculosis KZN 1435] 25 more sequence titles Length=506 Score = 936 bits (2419), Expect = 0.0, Method: Compositional matrix adjust. Identities = 474/475 (99%), Positives = 474/475 (99%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL Sbjct 32 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 91 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG Sbjct 92 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 151 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA Sbjct 152 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 211 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 212 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 271 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 272 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 331 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 332 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 391 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 392 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 451 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR Sbjct 452 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 506 >gi|31794934|ref|NP_857427.1| putative two component sensor kinase [Mycobacterium bovis AF2122/97] gi|121639678|ref|YP_979902.1| putative two component sensor kinase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224992174|ref|YP_002646863.1| putative two component sensor kinase [Mycobacterium bovis BCG str. Tokyo 172] 16 more sequence titles Length=475 Score = 933 bits (2411), Expect = 0.0, Method: Compositional matrix adjust. Identities = 472/475 (99%), Positives = 473/475 (99%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWR ETHNYIRSGPGPRFL Sbjct 1 MGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRRETHNYIRSGPGPRFL 60 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG Sbjct 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA Sbjct 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 241 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR Sbjct 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 >gi|289445363|ref|ZP_06435107.1| two component system sensor kinase [Mycobacterium tuberculosis CPHL_A] gi|289418321|gb|EFD15522.1| two component system sensor kinase [Mycobacterium tuberculosis CPHL_A] Length=475 Score = 931 bits (2407), Expect = 0.0, Method: Compositional matrix adjust. Identities = 471/475 (99%), Positives = 473/475 (99%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWR ETHNYIRSGPGPRFL Sbjct 1 MGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRRETHNYIRSGPGPRFL 60 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG Sbjct 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIA+VAATTAGIVIIKRALA Sbjct 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIAVVAATTAGIVIIKRALA 180 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 241 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR Sbjct 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 >gi|340628735|ref|YP_004747187.1| putative two component sensor kinase [Mycobacterium canettii CIPT 140010059] gi|340006925|emb|CCC46115.1| putative two component sensor kinase [Mycobacterium canettii CIPT 140010059] Length=475 Score = 918 bits (2372), Expect = 0.0, Method: Compositional matrix adjust. Identities = 466/475 (99%), Positives = 469/475 (99%), Gaps = 0/475 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWR ETHNYIR GPGPRFL Sbjct 1 MGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRRETHNYIRWGPGPRFL 60 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTST RSQLERIAGSRTPLTLDLDGLG Sbjct 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTARSQLERIAGSRTPLTLDLDGLG 120 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA Sbjct 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEVVDLPLDRGEV+LPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR Sbjct 181 PLRRVAQTASEVVDLPLDRGEVELPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV Sbjct 241 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL Sbjct 301 EDLLLLARLDSGRPLEREPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT Sbjct 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPG+TEFAVRLPLDGWQPL SSPR Sbjct 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGHTEFAVRLPLDGWQPLASSPR 475 >gi|342860016|ref|ZP_08716668.1| sensor histidine kinase [Mycobacterium colombiense CECT 3035] gi|342132394|gb|EGT85623.1| sensor histidine kinase [Mycobacterium colombiense CECT 3035] Length=509 Score = 758 bits (1957), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/469 (84%), Positives = 417/469 (89%), Gaps = 2/469 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VGITAATE+AL HLVAQLD QL GTSYRS LMYPE P WRH+ H Y R GPGPRFL Sbjct 32 VGITAATELALLHHLVAQLDGQLAGTSYRSALMYPEP-PHSGWRHQ-HVYPRPGPGPRFL 89 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVS G TV AGY T SG RA LT T + QL IAGSR P+TLDLDGLG Sbjct 90 DAPGQPAGMVAAVVSHGNTVDAGYTTSSGDRAELTPTAQRQLSGIAGSRKPVTLDLDGLG 149 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRV+AAPSRNG DVIVTGLSM N+D T+++ML+IFGIVTVIALVAATTAG++II+RALA Sbjct 150 RYRVVAAPSRNGGDVIVTGLSMANIDTTLMRMLVIFGIVTVIALVAATTAGVIIIRRALA 209 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTASEV LPL RGEV+LPVRV E DANPSTEVGQLG+ALN+MLDHIAAALSAR Sbjct 210 PLRRVAQTASEVAGLPLARGEVELPVRVREADANPSTEVGQLGAALNQMLDHIAAALSAR 269 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQR+GDD EAVA AMSRVASETER+TRLV Sbjct 270 QASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQAMSRVASETERMTRLV 329 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVD+SRLAVDAVSDAHVAGPDHQW LDLP EPVV+ GDAARL Sbjct 330 EDLLLLARLDSGRPLEREPVDLSRLAVDAVSDAHVAGPDHQWELDLPEEPVVVTGDAARL 389 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQV+ NLLANARVHTG GT+VTTRLST P+H VLQVIDNGPGIPAALQSEVFERFARGD+ Sbjct 390 HQVLANLLANARVHTGAGTVVTTRLSTEPSHTVLQVIDNGPGIPAALQSEVFERFARGDS 449 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQP 469 SRSR+ GSTGLGLAIVSAVVKAHNGTI V S+PG TEF VRLP DGWQP Sbjct 450 SRSRKGGSTGLGLAIVSAVVKAHNGTIAVDSAPGRTEFTVRLPPDGWQP 498 >gi|183985284|ref|YP_001853575.1| two-component sensor kinase TcrY [Mycobacterium marinum M] gi|183178610|gb|ACC43720.1| two-component sensor kinase TcrY [Mycobacterium marinum M] Length=504 Score = 747 bits (1929), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/468 (81%), Positives = 415/468 (89%), Gaps = 2/468 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VGITAATE+AL HLVAQLD QLGGTS+RS LMYPE R WRH+ H Y R GPGPRFL Sbjct 32 VGITAATELALHHHLVAQLDGQLGGTSHRSALMYPESSHRF-WRHQ-HRYWRPGPGPRFL 89 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMV AVV DG + AGYLT SG RA ++ T ++QL +AGS+ P+TL+LDGLG Sbjct 90 DAPGQPAGMVGAVVRDGKAIVAGYLTNSGDRAEISPTAQAQLAAVAGSQDPVTLNLDGLG 149 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRV++A SR G ++IVTGLSM +VDATM++MLIIFGIVT++ALVAATTAG +II+RALA Sbjct 150 RYRVVSALSRRGDELIVTGLSMSDVDATMIRMLIIFGIVTIVALVAATTAGAIIIRRALA 209 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTA+EVVDLPLDRGEV+LPVRV E DANP TEVGQLGSALNRMLDHIAAALS R Sbjct 210 PLRRVAQTATEVVDLPLDRGEVELPVRVSETDANPDTEVGQLGSALNRMLDHIAAALSTR 269 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTEL QR+GDD AVAHAMSRV SETERIT LV Sbjct 270 QASETRVRQFVADASHELRTPLAAIRGYTELAQRMGDDRAAVAHAMSRVGSETERITSLV 329 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVDMSRLAVDAVSDAHVAGPD QW LDLP EPVV+ GDAARL Sbjct 330 EDLLLLARLDSGRPLEREPVDMSRLAVDAVSDAHVAGPDQQWELDLPAEPVVVTGDAARL 389 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVV NLLANAR+HTGPG +VTTRLS+GPTHVVL+VIDNGPGIP A+QSE+FERFARGDT Sbjct 390 HQVVANLLANARIHTGPGAVVTTRLSSGPTHVVLEVIDNGPGIPEAMQSEIFERFARGDT 449 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQ 468 SRSR+ GSTGLGLAIV+AVVKAHNGTITV+SSPG TEF VRLPLD WQ Sbjct 450 SRSRKGGSTGLGLAIVAAVVKAHNGTITVNSSPGRTEFVVRLPLDAWQ 497 >gi|296166888|ref|ZP_06849305.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897765|gb|EFG77354.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=500 Score = 745 bits (1924), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/469 (82%), Positives = 419/469 (90%), Gaps = 1/469 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VGITA TE+AL HLV QLD QL GTS+RS LMYPE RP WRHE + R GPGPRFL Sbjct 27 VGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPEPK-RPGWRHEHSYFPRPGPGPRFL 85 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVV+ G + AGYLTGSG+RAALT ++QLERIA S P+TLDLDGLG Sbjct 86 DAPGQPAGMVAAVVNHGKAIDAGYLTGSGTRAALTPAAQAQLERIAASHAPVTLDLDGLG 145 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRV+AAPSRNG D+IVTGLSM N+DAT+++MLIIFGIVT IAL AAT AG++I++RALA Sbjct 146 RYRVMAAPSRNGGDIIVTGLSMSNIDATLIRMLIIFGIVTAIALAAATIAGVIIVRRALA 205 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTAS V DLPLDRGEV+LP+RV E DANP+TEVGQLGSALNRMLDHIAAALSAR Sbjct 206 PLRRVAQTASRVADLPLDRGEVELPLRVRESDANPATEVGQLGSALNRMLDHIAAALSAR 265 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQR+GDD EAVAHAMSRVASETER+TRLV Sbjct 266 QASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAHAMSRVASETERMTRLV 325 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVD+SR+A+DAV+DAHVAGPDHQW LDLP EPV++ GDAARL Sbjct 326 EDLLLLARLDSGRPLEREPVDLSRVALDAVNDAHVAGPDHQWELDLPEEPVIVTGDAARL 385 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQV+ NLLANAR+HTG GT+VTTRLS PTH VLQVIDNGPGIPA LQSEVFERFARGDT Sbjct 386 HQVLANLLANARLHTGAGTVVTTRLSAEPTHTVLQVIDNGPGIPAVLQSEVFERFARGDT 445 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQP 469 SRSR+ GSTGLGLAIVSAVV+AHNGTI V+SSPG+TEF VRLPL+GWQP Sbjct 446 SRSRKGGSTGLGLAIVSAVVRAHNGTIAVNSSPGHTEFTVRLPLNGWQP 494 >gi|118466581|ref|YP_879594.1| sensor histidine kinase [Mycobacterium avium 104] gi|118167868|gb|ABK68765.1| sensor histidine kinase [Mycobacterium avium 104] Length=496 Score = 741 bits (1912), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/473 (83%), Positives = 422/473 (90%), Gaps = 3/473 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITA TE+AL HLV QLD QL GTS+RS LMYPE P P RHE Y R GPGPRFL Sbjct 27 LGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPE--PNHP-RHEHSPYPRPGPGPRFL 83 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVS G TV AGYLT SG+R ALTST ++QLE+IAGSR P+T++LDGLG Sbjct 84 DAPGQPAGMVAAVVSHGKTVDAGYLTSSGTRDALTSTAQTQLEQIAGSRAPVTVNLDGLG 143 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRV+AAPSRNG D+IVTGLSM N+DAT+++ML+IFGIVTVIAL AAT AG+VII+RALA Sbjct 144 RYRVVAAPSRNGSDIIVTGLSMANIDATLIRMLVIFGIVTVIALAAATIAGVVIIRRALA 203 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTA EV DLPL RGEV+LPVRV E DANPSTEVGQLG+ALNRMLDHIA ALSAR Sbjct 204 PLRRVAQTAREVADLPLARGEVELPVRVRESDANPSTEVGQLGAALNRMLDHIADALSAR 263 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQR+GDD EAVA AMSRVASETER+TRLV Sbjct 264 QASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQAMSRVASETERMTRLV 323 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVD+SRLAVDAV+DAHVAGPDHQW LDLP EPVVI GDAARL Sbjct 324 EDLLLLARLDSGRPLEREPVDLSRLAVDAVNDAHVAGPDHQWELDLPEEPVVITGDAARL 383 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQV+TNLLANARVHTG GT+VTTRLST P H VLQVIDNGPGIPA LQSEVFERFARGD+ Sbjct 384 HQVLTNLLANARVHTGAGTVVTTRLSTEPAHTVLQVIDNGPGIPAELQSEVFERFARGDS 443 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESS 473 SRSR+ GSTGLGLAIVSAVVKAHNGTI+V+SSPG+TEF VRLP +GWQP S+ Sbjct 444 SRSRKGGSTGLGLAIVSAVVKAHNGTISVNSSPGHTEFTVRLPPNGWQPHASA 496 >gi|41406358|ref|NP_959194.1| hypothetical protein MAP0260 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394706|gb|AAS02577.1| hypothetical protein MAP_0260 [Mycobacterium avium subsp. paratuberculosis K-10] Length=496 Score = 740 bits (1911), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/473 (82%), Positives = 422/473 (90%), Gaps = 3/473 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITA TE+AL HLV QLD QL GTS+RS LMYPE P P RHE Y R GPGPRFL Sbjct 27 LGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPE--PNHP-RHEHSPYPRPGPGPRFL 83 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVS G TV AGYLT SG+R ALTST ++QLE+IAGSR P+T++LDGLG Sbjct 84 DAPGQPAGMVAAVVSHGKTVDAGYLTSSGARDALTSTAQTQLEQIAGSRAPVTVNLDGLG 143 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRV+AAPSRNG D+IVTGLSM N+DAT+++ML+IFGIVTVIAL AAT AG+VII+RALA Sbjct 144 RYRVVAAPSRNGSDIIVTGLSMANIDATLIRMLVIFGIVTVIALAAATIAGVVIIRRALA 203 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTA EV DLPL RGEV+LPVRV E DANPSTEVGQLG+ALNRMLDHIA ALSAR Sbjct 204 PLRRVAQTAREVADLPLARGEVELPVRVRESDANPSTEVGQLGAALNRMLDHIADALSAR 263 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQR+GDD EAVA AMSRVASETER+TRLV Sbjct 264 QASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQAMSRVASETERMTRLV 323 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVD+SRLAVDAV+DAHVAGPDHQW LDLP EPVV+ GDAARL Sbjct 324 EDLLLLARLDSGRPLEREPVDLSRLAVDAVNDAHVAGPDHQWELDLPEEPVVVTGDAARL 383 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQV+TNLLANARVHTG GT+VTTRLST P H VLQVIDNGPGIPA LQSEVFERFARGD+ Sbjct 384 HQVLTNLLANARVHTGAGTVVTTRLSTEPAHTVLQVIDNGPGIPAELQSEVFERFARGDS 443 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESS 473 SRSR+ GSTGLGLAIVSAVVKAHNGTI+V+SSPG+TEF VRLP +GWQP S+ Sbjct 444 SRSRKGGSTGLGLAIVSAVVKAHNGTISVNSSPGHTEFTVRLPPNGWQPHASA 496 >gi|336460749|gb|EGO39637.1| signal transduction histidine kinase [Mycobacterium avium subsp. paratuberculosis S397] Length=519 Score = 739 bits (1909), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/473 (82%), Positives = 422/473 (90%), Gaps = 3/473 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITA TE+AL HLV QLD QL GTS+RS LMYPE P P RHE Y R GPGPRFL Sbjct 50 LGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPE--PNHP-RHEHSPYPRPGPGPRFL 106 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVVS G TV AGYLT SG+R ALTST ++QLE+IAGSR P+T++LDGLG Sbjct 107 DAPGQPAGMVAAVVSHGKTVDAGYLTSSGARDALTSTAQTQLEQIAGSRAPVTVNLDGLG 166 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRV+AAPSRNG D+IVTGLSM N+DAT+++ML+IFGIVTVIAL AAT AG+VII+RALA Sbjct 167 RYRVVAAPSRNGSDIIVTGLSMANIDATLIRMLVIFGIVTVIALAAATIAGVVIIRRALA 226 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTA EV DLPL RGEV+LPVRV E DANPSTEVGQLG+ALNRMLDHIA ALSAR Sbjct 227 PLRRVAQTAREVADLPLARGEVELPVRVRESDANPSTEVGQLGAALNRMLDHIADALSAR 286 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQR+GDD EAVA AMSRVASETER+TRLV Sbjct 287 QASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQAMSRVASETERMTRLV 346 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVD+SRLAVDAV+DAHVAGPDHQW LDLP EPVV+ GDAARL Sbjct 347 EDLLLLARLDSGRPLEREPVDLSRLAVDAVNDAHVAGPDHQWELDLPEEPVVVTGDAARL 406 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQV+TNLLANARVHTG GT+VTTRLST P H VLQVIDNGPGIPA LQSEVFERFARGD+ Sbjct 407 HQVLTNLLANARVHTGAGTVVTTRLSTEPAHTVLQVIDNGPGIPAELQSEVFERFARGDS 466 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESS 473 SRSR+ GSTGLGLAIVSAVVKAHNGTI+V+SSPG+TEF VRLP +GWQP S+ Sbjct 467 SRSRKGGSTGLGLAIVSAVVKAHNGTISVNSSPGHTEFTVRLPPNGWQPHASA 519 >gi|254773314|ref|ZP_05214830.1| sensor histidine kinase [Mycobacterium avium subsp. avium ATCC 25291] Length=496 Score = 738 bits (1906), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/473 (82%), Positives = 421/473 (90%), Gaps = 3/473 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GITA TE+AL HLV QLD QL GTS+RS LMYPE P P RHE Y R GPGPRFL Sbjct 27 LGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPE--PNHP-RHEHSPYPRPGPGPRFL 83 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAGMVAAVV G TV AGYLT SG+R ALTST ++QLE+IAGSR P+T++LDGLG Sbjct 84 DAPGQPAGMVAAVVGHGKTVDAGYLTSSGTRDALTSTAQTQLEQIAGSRAPVTVNLDGLG 143 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRV+AAPSRNG D+IVTGLSM N+DAT+++ML+IFGIVTVIAL AAT AG+VII+RALA Sbjct 144 RYRVVAAPSRNGSDIIVTGLSMANIDATLIRMLVIFGIVTVIALAAATIAGVVIIRRALA 203 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTA EV DLPL RGEV+LPVRV E DANPSTEVGQLG+ALNRMLDHIA ALSAR Sbjct 204 PLRRVAQTAREVADLPLARGEVELPVRVRESDANPSTEVGQLGAALNRMLDHIADALSAR 263 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTELTQR+GDD EAVA AMSRVASETER+TRLV Sbjct 264 QASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQAMSRVASETERMTRLV 323 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVD+SRLAVDAV+DAHVAGPDHQW LDLP EPVV+ GDAARL Sbjct 324 EDLLLLARLDSGRPLEREPVDLSRLAVDAVNDAHVAGPDHQWELDLPEEPVVVTGDAARL 383 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQV+TNLLANARVHTG GT+VTTRLST P H VLQVIDNGPGIPA LQSEVFERFARGD+ Sbjct 384 HQVLTNLLANARVHTGAGTVVTTRLSTEPAHTVLQVIDNGPGIPAELQSEVFERFARGDS 443 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESS 473 SRSR+ GSTGLGLAIVSAVVKAHNGTI+V+SSPG+TEF VRLP +GWQP S+ Sbjct 444 SRSRKGGSTGLGLAIVSAVVKAHNGTISVNSSPGHTEFTVRLPPNGWQPHASA 496 >gi|240168528|ref|ZP_04747187.1| hypothetical protein MkanA1_04397 [Mycobacterium kansasii ATCC 12478] Length=477 Score = 733 bits (1891), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/469 (82%), Positives = 419/469 (90%), Gaps = 5/469 (1%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GI AATE+ALR HL+ QLD QL G SYRS L+YPE PP RHE Y+R+GPGP+FL Sbjct 8 IGIAAATELALRHHLLKQLDGQLSGASYRSSLLYPE----PPRRHEP-RYVRTGPGPKFL 62 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 DAPGQPAG+VAAVVS+G T+ AGYLTGSG+RAAL+ ++QL IAGSR P+TL+LDGLG Sbjct 63 DAPGQPAGLVAAVVSNGKTIDAGYLTGSGARAALSDKAQAQLAAIAGSRIPVTLNLDGLG 122 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 RYRV+AAPSRN DVIVTGLSM +DATML+ML++FGIVT +AL+AATTAG +II+RALA Sbjct 123 RYRVVAAPSRNRTDVIVTGLSMSGIDATMLRMLVMFGIVTAVALLAATTAGAMIIRRALA 182 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PLRRVAQTA+EVVDLPLDRGEV LPVRV + DANP TEVGQLGSALNRMLDHIAAALS R Sbjct 183 PLRRVAQTATEVVDLPLDRGEVALPVRVSDTDANPYTEVGQLGSALNRMLDHIAAALSTR 242 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLV 300 QASET VRQFVADASHELRTPLAAIRGYTEL QR+ DD EAVAHAMSRVASETERITRLV Sbjct 243 QASETRVRQFVADASHELRTPLAAIRGYTELAQRMSDDREAVAHAMSRVASETERITRLV 302 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLDSGRPLER PVD+S LAVDAVSDAH+AGPDH+W LDLPPEPVV+ GD ARL Sbjct 303 EDLLLLARLDSGRPLEREPVDLSHLAVDAVSDAHIAGPDHKWELDLPPEPVVVTGDVARL 362 Query 361 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 HQVVTNLLANAR+HTGPGT+VTTRLS P H +LQV+DNGPGIP LQSEVFERFARGDT Sbjct 363 HQVVTNLLANARIHTGPGTVVTTRLSVEPAHALLQVVDNGPGIPVGLQSEVFERFARGDT 422 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQP 469 SRSR+ GSTGLGLAIVSAVVKAHNGTITV+SSPG+TEFAVRLPLDGWQP Sbjct 423 SRSRKGGSTGLGLAIVSAVVKAHNGTITVNSSPGHTEFAVRLPLDGWQP 471 >gi|254822465|ref|ZP_05227466.1| sensor histidine kinase [Mycobacterium intracellulare ATCC 13950] Length=485 Score = 728 bits (1878), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/470 (81%), Positives = 415/470 (89%), Gaps = 2/470 (0%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYI-RSGPGPRF 59 VGITA TE+AL HLV QLD QL GTS+RS LMYPE P W H H+Y R GPGPRF Sbjct 13 VGITAVTELALNHHLVKQLDGQLAGTSFRSALMYPEPN-HPGWHHHQHSYYPRPGPGPRF 71 Query 60 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGL 119 LDAPGQPAGMVAAVVS G TV AGYLT SG+R LT T ++QLE+IAG+R P+TL+LDGL Sbjct 72 LDAPGQPAGMVAAVVSHGKTVDAGYLTSSGTRDDLTPTAQTQLEQIAGNRAPVTLNLDGL 131 Query 120 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRAL 179 GRYRV+AAPSRNG D+IVTGLSM N+DAT+++ML+IFGIVT +AL AAT AG+VII+RAL Sbjct 132 GRYRVVAAPSRNGSDIIVTGLSMSNIDATLIRMLVIFGIVTAVALAAATIAGVVIIRRAL 191 Query 180 APLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSA 239 APLRRVAQTA +V DLPL RGEV+LPVRV E DANPSTEVGQLG++LNRMLDHIA ALSA Sbjct 192 APLRRVAQTAGQVADLPLSRGEVELPVRVRESDANPSTEVGQLGASLNRMLDHIAEALSA 251 Query 240 RQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRL 299 RQASET VRQFVADASHELRTPLAAIRGYTELTQR+GDD EAVA AMSRVASETER+TRL Sbjct 252 RQASETRVRQFVADASHELRTPLAAIRGYTELTQRMGDDREAVAQAMSRVASETERMTRL 311 Query 300 VEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAAR 359 VEDLLLLARLDSGRPLER VD+SRLAVDAV+DAHVAGPDHQW LDLP EPVV+ GDAAR Sbjct 312 VEDLLLLARLDSGRPLERESVDLSRLAVDAVNDAHVAGPDHQWELDLPEEPVVVTGDAAR 371 Query 360 LHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGD 419 LHQV+TNLLANARVHTG GT+VTTRLST P+H VLQVIDNGPGIPAALQSEVFERFARGD Sbjct 372 LHQVLTNLLANARVHTGAGTVVTTRLSTEPSHTVLQVIDNGPGIPAALQSEVFERFARGD 431 Query 420 TSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQP 469 +SRSR+ GSTGLGLAIVSAVV+AHNGTI V SSPG TEF VRLP +GWQP Sbjct 432 SSRSRKGGSTGLGLAIVSAVVRAHNGTIAVDSSPGRTEFTVRLPPNGWQP 481 >gi|333992681|ref|YP_004525295.1| two-component sensor kinase TcrY [Mycobacterium sp. JDM601] gi|333488649|gb|AEF38041.1| two-component sensor kinase TcrY [Mycobacterium sp. JDM601] Length=506 Score = 547 bits (1409), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 310/472 (66%), Positives = 365/472 (78%), Gaps = 10/472 (2%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 +GI A TE+AL ++LV+QLD+QL + RS ++ + P P H + R GPGP FL Sbjct 37 LGIGAVTELALYQYLVSQLDHQLSDAARRSARLHGQ--PPAPPGHRPRHRPRPGPGPDFL 94 Query 61 DAPGQPAGMVAAVVS--DGT--TVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDL 116 DAPGQP GMV AVV DG AG L+ SG R L+++ +QL I P+T L Sbjct 95 DAPGQPVGMVGAVVDSVDGEDRIADAGCLSTSGLREELSASATTQLAGIVAEPAPVTRRL 154 Query 117 DGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIK 176 DG+GRYR++A +R+G + I+ GL + V+ATM+++L+IFG+VT++A+ AA TAG V+ + Sbjct 155 DGVGRYRLVATNARHGGETIIIGLPLAAVNATMVRVLLIFGLVTLVAVAAAATAGSVVTR 214 Query 177 RALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAA 236 RALAPLRRVAQTA EV DLPLDRGE LPVRV E D NP TEVGQLG+A+NRMLDHIAAA Sbjct 215 RALAPLRRVAQTAGEVADLPLDRGEATLPVRVAESDTNPRTEVGQLGAAVNRMLDHIAAA 274 Query 237 LSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRI----GDDPEAVAHAMSRVASE 292 L+ RQASET VRQFVADASHELRTPL AIRGYTEL QRI G D E++AHA+SRV SE Sbjct 275 LANRQASETRVRQFVADASHELRTPLTAIRGYTELAQRIPVADGVDSESLAHALSRVQSE 334 Query 293 TERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVV 352 T+R+T+LVEDLLLLARLDSGRPLE PVD+SRLAVDAVSDAHV GPDHQW LDLP EPV Sbjct 335 TQRMTQLVEDLLLLARLDSGRPLEHEPVDLSRLAVDAVSDAHVGGPDHQWELDLPDEPVT 394 Query 353 IPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVF 412 +PGDAARLHQV+TNLL NARVHTG GT+VTTRL VL V D+GPGIPA Q E+F Sbjct 395 VPGDAARLHQVLTNLLTNARVHTGAGTVVTTRLGVDGAEAVLCVTDDGPGIPAEFQPEIF 454 Query 413 ERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 ERFARGDTSRSR+ GSTGLGLAI SAVV+AH GTI V+S PG+TEF VRLPL Sbjct 455 ERFARGDTSRSRKGGSTGLGLAIASAVVRAHRGTIAVTSRPGHTEFTVRLPL 506 >gi|119870029|ref|YP_939981.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium sp. KMS] gi|119696118|gb|ABL93191.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium sp. KMS] Length=517 Score = 520 bits (1339), Expect = 2e-145, Method: Compositional matrix adjust. Identities = 296/473 (63%), Positives = 340/473 (72%), Gaps = 16/473 (3%) Query 7 TEMALRRHLVAQLDNQLGGTSYRSVLMYP-----------EKMPRPPWRHETHNYIR--S 53 TE+AL+R LV QLD QL T+ RSV ++ PP IR S Sbjct 32 TELALQRFLVNQLDTQLDETARRSVGLFAFGPPPPPLMLPAPRFPPPPGFPHRRIIRDDS 91 Query 54 GPGPRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLT 113 GPGP FL+APGQ A V AVV GT V AG +T G R ++ T QL + P T Sbjct 92 GPGPAFLNAPGQAARTVGAVVDRGTAVDAGVITADGERVEVSGTAAGQLAGVPADEVPRT 151 Query 114 LDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIV 173 L LDGLGRYRV+A P+R +VIVTGL M +VD T+L +L+IF +V IAL+ AT AG+ Sbjct 152 LALDGLGRYRVIALPARGPAEVIVTGLPMSDVDDTLLTVLVIFCVVAAIALIGATAAGVW 211 Query 174 IIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPD-ANPSTEVGQLGSALNRMLDH 232 II+R LAPL RV+ A EV DL LDRGEV+LP + D A+ TEVGQLG++LNRMLD Sbjct 212 IIRRQLAPLSRVSAAAREVADLELDRGEVRLPTPIVTVDPASAHTEVGQLGTSLNRMLDR 271 Query 233 IAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVAS 291 IA ALSAR ASET VRQFVADASHELRTPLAAIRGYTEL QR D P VAHAM+RV S Sbjct 272 IAGALSARHASETRVRQFVADASHELRTPLAAIRGYTELAQRHSDALPGDVAHAMNRVES 331 Query 292 ETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPV 351 ET R+TRLVED+LLLARLD GRPLER PVD+SRL VDAVSDAH AGPDH W+L+LP EPV Sbjct 332 ETARMTRLVEDMLLLARLDDGRPLEREPVDLSRLVVDAVSDAHAAGPDHVWSLELPEEPV 391 Query 352 VIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPT-HVVLQVIDNGPGIPAALQSE 410 V+ GD ARLHQV+ NLLANARVHT GT V T L+ G VL V D+GPGIP +LQ E Sbjct 392 VVDGDEARLHQVLGNLLANARVHTPAGTTVVTALAVGADGGAVLTVTDDGPGIPPSLQPE 451 Query 411 VFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 +FERFARGD+SRSR+ GSTGLGLAIV+AVVKAH+GTI V S+PG TEF VRLP Sbjct 452 IFERFARGDSSRSRRGGSTGLGLAIVAAVVKAHSGTIEVDSAPGRTEFVVRLP 504 >gi|108800889|ref|YP_641086.1| periplasmic sensor signal transduction histidine kinase [Mycobacterium sp. MCS] gi|108771308|gb|ABG10030.1| periplasmic sensor signal transduction histidine kinase [Mycobacterium sp. MCS] Length=532 Score = 519 bits (1336), Expect = 4e-145, Method: Compositional matrix adjust. Identities = 296/473 (63%), Positives = 340/473 (72%), Gaps = 16/473 (3%) Query 7 TEMALRRHLVAQLDNQLGGTSYRSVLMYP-----------EKMPRPPWRHETHNYIR--S 53 TE+AL+R LV QLD QL T+ RSV ++ PP IR S Sbjct 47 TELALQRFLVNQLDTQLDETARRSVGLFAFGPPPPPLMLPAPRFPPPPGFPHRRIIRDDS 106 Query 54 GPGPRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLT 113 GPGP FL+APGQ A V AVV GT V AG +T G R ++ T QL + P T Sbjct 107 GPGPAFLNAPGQAARTVGAVVDRGTAVDAGVITADGERVEVSGTAAGQLAGVPADEVPRT 166 Query 114 LDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIV 173 L LDGLGRYRV+A P+R +VIVTGL M +VD T+L +L+IF +V IAL+ AT AG+ Sbjct 167 LALDGLGRYRVIALPARGPAEVIVTGLPMSDVDDTLLTVLVIFCVVAAIALIGATAAGVW 226 Query 174 IIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPD-ANPSTEVGQLGSALNRMLDH 232 II+R LAPL RV+ A EV DL LDRGEV+LP + D A+ TEVGQLG++LNRMLD Sbjct 227 IIRRQLAPLSRVSAAAREVADLELDRGEVRLPTPIVTVDPASAHTEVGQLGTSLNRMLDR 286 Query 233 IAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVAS 291 IA ALSAR ASET VRQFVADASHELRTPLAAIRGYTEL QR D P VAHAM+RV S Sbjct 287 IAGALSARHASETRVRQFVADASHELRTPLAAIRGYTELAQRHSDALPGDVAHAMNRVES 346 Query 292 ETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPV 351 ET R+TRLVED+LLLARLD GRPLER PVD+SRL VDAVSDAH AGPDH W+L+LP EPV Sbjct 347 ETARMTRLVEDMLLLARLDDGRPLEREPVDLSRLVVDAVSDAHAAGPDHVWSLELPEEPV 406 Query 352 VIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPT-HVVLQVIDNGPGIPAALQSE 410 V+ GD ARLHQV+ NLLANARVHT GT V T L+ G VL V D+GPGIP +LQ E Sbjct 407 VVDGDEARLHQVLGNLLANARVHTPAGTTVVTALAVGADGGAVLTVTDDGPGIPPSLQPE 466 Query 411 VFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 +FERFARGD+SRSR+ GSTGLGLAIV+AVVKAH+GTI V S+PG TEF VRLP Sbjct 467 IFERFARGDSSRSRRGGSTGLGLAIVAAVVKAHSGTIEVDSAPGRTEFVVRLP 519 >gi|126436515|ref|YP_001072206.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium sp. JLS] gi|126236315|gb|ABN99715.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium sp. JLS] Length=532 Score = 517 bits (1332), Expect = 1e-144, Method: Compositional matrix adjust. Identities = 295/473 (63%), Positives = 339/473 (72%), Gaps = 16/473 (3%) Query 7 TEMALRRHLVAQLDNQLGGTSYRSVLMYP-----------EKMPRPPWRHETHNYIR--S 53 TE+AL+R LV QLD QL T+ RSV ++ PP IR S Sbjct 47 TELALQRFLVNQLDTQLDETARRSVGLFAFGPPPPPLMLPAPRFPPPPGFPHRRIIRDDS 106 Query 54 GPGPRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLT 113 GPGP FL+APGQ A V AVV GT V AG +T G R ++ QL + P T Sbjct 107 GPGPAFLNAPGQAARTVGAVVDRGTAVDAGVITADGERVEVSGAAAGQLAGVPADEVPRT 166 Query 114 LDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIV 173 L LDGLGRYRV+A P+R +VIVTGL M +VD T+L +L+IF +V IAL+ AT AG+ Sbjct 167 LTLDGLGRYRVIALPARGPAEVIVTGLPMSDVDDTLLTVLVIFCVVAAIALIGATAAGVW 226 Query 174 IIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPD-ANPSTEVGQLGSALNRMLDH 232 II+R LAPL RV+ A EV DL LDRGEV+LP + D A+ TEVGQLG++LNRMLD Sbjct 227 IIRRQLAPLSRVSAAAREVADLELDRGEVRLPTPIVTVDPASAHTEVGQLGTSLNRMLDR 286 Query 233 IAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVAS 291 IA ALSAR ASET VRQFVADASHELRTPLAAIRGYTEL QR D P VAHAM+RV S Sbjct 287 IAGALSARHASETRVRQFVADASHELRTPLAAIRGYTELAQRHSDALPGDVAHAMNRVES 346 Query 292 ETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPV 351 ET R+TRLVED+LLLARLD GRPLER PVD+SRL VDAVSDAH AGPDH W+L+LP EPV Sbjct 347 ETARMTRLVEDMLLLARLDDGRPLEREPVDLSRLVVDAVSDAHAAGPDHVWSLELPEEPV 406 Query 352 VIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPT-HVVLQVIDNGPGIPAALQSE 410 V+ GD ARLHQV+ NLLANARVHT GT V T L+ G VL V D+GPGIP +LQ E Sbjct 407 VVDGDEARLHQVLGNLLANARVHTPAGTTVVTALAVGADGGAVLTVTDDGPGIPPSLQPE 466 Query 411 VFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 +FERFARGD+SRSR+ GSTGLGLAIV+AVVKAH+GTI V S+PG TEF VRLP Sbjct 467 IFERFARGDSSRSRRGGSTGLGLAIVAAVVKAHSGTIEVDSAPGRTEFVVRLP 519 >gi|120405381|ref|YP_955210.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium vanbaalenii PYR-1] gi|119958199|gb|ABM15204.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium vanbaalenii PYR-1] Length=534 Score = 488 bits (1255), Expect = 1e-135, Method: Compositional matrix adjust. Identities = 293/498 (59%), Positives = 340/498 (69%), Gaps = 32/498 (6%) Query 7 TEMALRRHLVAQLDNQLGGTSYRSVLMYP-----------------EKMPRPPWRHETHN 49 TE AL+R L+ QLD Q+ RS +++ M PP + H Sbjct 33 TEFALQRFLMNQLDEQVVEAGRRSSVIFELGPPPPPGMRPPPMPPPGAMVAPPPPGQGHR 92 Query 50 YI---RSGPGPRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIA 106 + GPGP FL+APGQ V A+VS G AG +T GSRA +++T QL +A Sbjct 93 IVIRDDQGPGPAFLNAPGQAIYTVGALVSAGQVEEAGVITADGSRAQVSATAAGQLAAVA 152 Query 107 GSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVA 166 P T+DLDGLGRYRV+A P+ V+V GL G+VD T+ + +IFG V +ALVA Sbjct 153 VDERPHTVDLDGLGRYRVVAFPAHIPGQVVVAGLPTGDVDDTLFWVAVIFGAVGAVALVA 212 Query 167 ATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPD-ANPSTEVGQLGSA 225 A TAGIVI++R LAPL RV+ A +V DL LDRGEV LP + + D A TEVGQLG+A Sbjct 213 AGTAGIVIVRRQLAPLARVSAAARQVADLELDRGEVNLPTPIVKVDPAAEHTEVGQLGTA 272 Query 226 LNRMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAH 284 LNRMLD IA ALSAR ASET VRQFVADASHELRTPLAAIRGYTEL QR PE VAH Sbjct 273 LNRMLDRIAGALSARHASETRVRQFVADASHELRTPLAAIRGYTELAQRKQAQLPEDVAH 332 Query 285 AMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWAL 344 AM+RV SETER+T+LVED+LLLARLDSGRPL+R VD++RL VDAVSDAHVAGPDH W L Sbjct 333 AMNRVESETERMTQLVEDMLLLARLDSGRPLDRETVDLTRLVVDAVSDAHVAGPDHAWEL 392 Query 345 DLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGP-THVVLQVIDNGPGI 403 DLP EPV + GD ARLHQV+ NLLANAR+HT GT+VTT L G VL V+D+GPGI Sbjct 393 DLPDEPVTVQGDEARLHQVLANLLANARIHTPAGTVVTTSLGVGDGGSAVLTVLDDGPGI 452 Query 404 PAALQSEVFERFARGDTSRSRQ--------AGSTGLGLAIVSAVVKAHNGTITVSSSPGY 455 P LQ EVFERFARGDTSRSR+ GSTGLGLAIV+AVV+AH GTI V S PG Sbjct 453 PDGLQPEVFERFARGDTSRSRRGDTSRSRGGGSTGLGLAIVAAVVRAHGGTIDVHSVPGR 512 Query 456 TEFAVRLPLDGWQPLESS 473 TEF V LP D QP SS Sbjct 513 TEFVVTLPGDS-QPGHSS 529 >gi|145222855|ref|YP_001133533.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium gilvum PYR-GCK] gi|315443320|ref|YP_004076199.1| signal transduction histidine kinase [Mycobacterium sp. Spyr1] gi|145215341|gb|ABP44745.1| integral membrane sensor signal transduction histidine kinase [Mycobacterium gilvum PYR-GCK] gi|315261623|gb|ADT98364.1| signal transduction histidine kinase [Mycobacterium sp. Spyr1] Length=546 Score = 469 bits (1207), Expect = 5e-130, Method: Compositional matrix adjust. Identities = 285/496 (58%), Positives = 342/496 (69%), Gaps = 32/496 (6%) Query 2 GITAATEMALRRHLVAQLDNQLGGTSYRSVLMYP-------------------------- 35 G+ ATE AL+R L+ QLD Q+ RS +++ Sbjct 41 GVGVATEFALQRFLMNQLDEQVIEAGRRSSMIFEFGPPPPPGMGMPPPPGVGMPPPPGVG 100 Query 36 --EKMPRPPWRHETHNYIR-SGPGPRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRA 92 PP R H IR GPGP FL+APGQ V AVVSDG AG + GSR Sbjct 101 MPVPPVGPPPRRGHHMMIRDEGPGPAFLNAPGQAILTVGAVVSDGRADDAGMIATDGSRT 160 Query 93 ALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQM 152 ++ QL +A P T+DLDGLGRYRV+A PS + +V GL +VD T+ + Sbjct 161 EISDVAARQLATVAVGGRPHTVDLDGLGRYRVVAFPSHMEGEAVVAGLPTTDVDDTLFWV 220 Query 153 LIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPD 212 +IFG+V V+AL+AA TAG VI++R LAPL RV++ A +V DL LDRGEV+LP + + D Sbjct 221 AVIFGVVAVVALMAAGTAGAVIVRRQLAPLARVSEAAQQVADLELDRGEVRLPTPIVKVD 280 Query 213 -ANPSTEVGQLGSALNRMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTEL 271 A TEVGQLGSALNRMLD IA ALSAR ASET VRQFVADASHELRTPLAAIRGYTEL Sbjct 281 PAAAQTEVGQLGSALNRMLDRIAGALSARHASETRVRQFVADASHELRTPLAAIRGYTEL 340 Query 272 TQRIGDD-PEAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAV 330 QR + P+ VAHAMSRV SET R+T+LVED+LLLARLD+GRPL+R VD++RL VDAV Sbjct 341 AQRKQAELPDDVAHAMSRVESETARMTQLVEDMLLLARLDTGRPLDRDSVDLTRLVVDAV 400 Query 331 SDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPT 390 SDAHVA PDH W LDLP EP+ + GD ARLHQV+ NLLANA +HT GT VTT L+ T Sbjct 401 SDAHVAAPDHVWELDLPDEPLTVCGDEARLHQVLANLLANAGIHTPAGTTVTTSLTATDT 460 Query 391 -HVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITV 449 V+++V+D+GPGIPA LQ +VFERFARGDTSRSR+ GSTGLGLAIV+AVV+AH+GTI++ Sbjct 461 GDVLVRVVDDGPGIPARLQPDVFERFARGDTSRSRRGGSTGLGLAIVAAVVRAHHGTISL 520 Query 450 SSSPGYTEFAVRLPLD 465 S PG TEFAV LP D Sbjct 521 HSVPGRTEFAVVLPGD 536 >gi|118470188|ref|YP_889240.1| sensor histidine kinase [Mycobacterium smegmatis str. MC2 155] gi|118171475|gb|ABK72371.1| sensor histidine kinase [Mycobacterium smegmatis str. MC2 155] Length=527 Score = 461 bits (1185), Expect = 2e-127, Method: Compositional matrix adjust. Identities = 281/479 (59%), Positives = 330/479 (69%), Gaps = 16/479 (3%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMP------------RPPWRHETH 48 + I ATE AL+R L+ QLD QL RS +Y P PP RH Sbjct 44 LSIGLATEFALQRFLMHQLDEQLLEAGRRSAAIYELPPPPRGFLPLFPPGMGPPGRHLRV 103 Query 49 NYIRSGPGPRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGS 108 GPGP FL+APGQ A V AVVS +V AG +T G R +++ QL I + Sbjct 104 FDPEQGPGPGFLNAPGQAARTVGAVVSPDGSVDAGVITSDGDRQEVSAAAARQLAAIPAT 163 Query 109 RTPLTLDLDGLGRYRVLAA-PSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAA 167 R P T+DLDGLGRYR++ P G IVTGL VD T+L +L +F ++ +AL+AA Sbjct 164 REPQTIDLDGLGRYRLIGLHPRHGGPQTIVTGLPNSVVDDTLLWVLGMFCVIAAVALIAA 223 Query 168 TTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVR-VPEPDANPSTEVGQLGSAL 226 TAG ++I+R APL RV+ TA EV DL L+RGEV+LP VP A TEVGQLG++L Sbjct 224 ITAGTLLIRRQFAPLARVSATAREVADLELERGEVRLPTPIVPVDPAVAHTEVGQLGTSL 283 Query 227 NRMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRI-GDDPEAVAHA 285 NRMLD IA+ALSAR ASET VRQFVADASHELRTPLAAIRGYTEL QR G+ P+ VAHA Sbjct 284 NRMLDRIASALSARHASETRVRQFVADASHELRTPLAAIRGYTELAQRKRGELPDDVAHA 343 Query 286 MSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALD 345 MSRV SET R+T+LVED+LLLARLD+GRPLER V++SRL VD VSDAHVAGP H+W+LD Sbjct 344 MSRVESETSRMTQLVEDMLLLARLDAGRPLERDRVELSRLVVDTVSDAHVAGPQHKWSLD 403 Query 346 LPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLST-GPTHVVLQVIDNGPGIP 404 LP + VVI GD ARLHQV+ NLLANAR HT PGT VT LS V + V D+GPGI Sbjct 404 LPEDAVVIDGDEARLHQVMANLLANARTHTPPGTSVTVALSADAEGWVTVAVTDDGPGIA 463 Query 405 AALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 L +VFERFARGD+SRSR+ GSTGLGLAIV+AVVKAH G I V+S PG T F VRLP Sbjct 464 PELLPDVFERFARGDSSRSRREGSTGLGLAIVAAVVKAHGGVIDVTSRPGETRFVVRLP 522 >gi|296394074|ref|YP_003658958.1| integral membrane sensor signal transduction histidine kinase [Segniliparus rotundus DSM 44985] gi|296181221|gb|ADG98127.1| integral membrane sensor signal transduction histidine kinase [Segniliparus rotundus DSM 44985] Length=506 Score = 438 bits (1126), Expect = 1e-120, Method: Compositional matrix adjust. Identities = 270/465 (59%), Positives = 322/465 (70%), Gaps = 8/465 (1%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VG+ T +A+ R+L QLD QL S RSV+++ + PP + +RSGPGP FL Sbjct 37 VGVGTGTMLAMDRYLFGQLDAQLRDASGRSVVLF--DLGPPP--QLADDKVRSGPGPIFL 92 Query 61 DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLG 120 +APGQ G V AV++ G A +T SG+R L T QL A T+ LDGLG Sbjct 93 NAPGQSIGTVGAVMAGGRVAEAAVITSSGARQRLAETAYRQLA-AAPRDHAATMRLDGLG 151 Query 121 RYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 YRVL AP+ +G +V VTGL V +T+L + IF V AL A AG +I++R L Sbjct 152 DYRVLKAPASDGTEV-VTGLPAAEVQSTLLSVFGIFCAVAAAALGFALVAGTLIVRRELV 210 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPS-TEVGQLGSALNRMLDHIAAALSA 239 PL +VA A EV DL LDRGEV+LP + + D + S TEVGQLG+ALNRM+ IA ALSA Sbjct 211 PLSQVADAAQEVADLDLDRGEVELPTPIVQMDPDRSHTEVGQLGAALNRMIARIADALSA 270 Query 240 RQASETCVRQFVADASHELRTPLAAIRGYTELTQR-IGDDPEAVAHAMSRVASETERITR 298 R ASET VRQFVADASHELRTPLA IRGYTEL QR + + P VAHAM RV +E R+T Sbjct 271 RHASETRVRQFVADASHELRTPLAVIRGYTELAQRDLAEVPAEVAHAMGRVGAEAVRMTG 330 Query 299 LVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAA 358 LVEDLLLLARLDSG LE+ PVD+S+L VDAVSD HVA PDH W+LD+P EPVV+PGD A Sbjct 331 LVEDLLLLARLDSGPLLEKKPVDLSQLVVDAVSDIHVAAPDHLWSLDIPDEPVVVPGDCA 390 Query 359 RLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARG 418 RLHQVV NLL+N R HT PGT VT L+ + VL V D+GPGIPAA QSE+FERF RG Sbjct 391 RLHQVVANLLSNCRAHTPPGTSVTVALAATTSDAVLTVADDGPGIPAAQQSEIFERFVRG 450 Query 419 DTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 D+SRSR++G TGLGLAI +AVV AH+G ITV SSPG T F V LP Sbjct 451 DSSRSRRSGGTGLGLAIAAAVVGAHDGDITVRSSPGDTVFTVTLP 495 >gi|169629668|ref|YP_001703317.1| putative two component sensor kinase [Mycobacterium abscessus ATCC 19977] gi|169241635|emb|CAM62663.1| Putative two component sensor kinase [Mycobacterium abscessus] Length=470 Score = 419 bits (1077), Expect = 5e-115, Method: Compositional matrix adjust. Identities = 253/469 (54%), Positives = 305/469 (66%), Gaps = 19/469 (4%) Query 11 LRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPP---------WRHETHNYIRSGPGPRFLD 61 + R L QLD Q+ RSV+++ P P WR GPGP FLD Sbjct 1 MNRFLNTQLDEQVRDAGNRSVVLFELGPPPPLSLPRPLANGWRPT------DGPGPAFLD 54 Query 62 APGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGR 121 APGQ GMV AV +G A +T GSR L+ ++E + T T+DLD G Sbjct 55 APGQSIGMVGAVAVNGHVTEAARITADGSRERLSPQACREVEGLLQQSTS-TVDLDHAGL 113 Query 122 YRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAP 181 YR++ P+ NG VIVTGL V T+ + I +V AL+ A AGIVII+R L P Sbjct 114 YRLVTMPT-NGGAVIVTGLPAEGVGQTLSSVFGIICVVGAAALITAIGAGIVIIRRQLDP 172 Query 182 LRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPS-TEVGQLGSALNRMLDHIAAALSAR 240 L +VA A EV +L L RGEV LP + + +N + TE+GQLG+ALNRML+ I ALSAR Sbjct 173 LSQVATAAQEVAELELHRGEVNLPTPIIDVASNRTHTELGQLGAALNRMLERIDDALSAR 232 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERITRL 299 SET VRQFVADASHELRTPLAAI GY EL +R D P VAHAMSRV SE R+T L Sbjct 233 HVSETRVRQFVADASHELRTPLAAISGYAELARRNHDALPTDVAHAMSRVQSEAARMTEL 292 Query 300 VEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAAR 359 VEDLLLLARLDSGRPL + PVD+SRL VDA SDAH+A +H+W L+LP +PV++ GD R Sbjct 293 VEDLLLLARLDSGRPLAQEPVDLSRLVVDAASDAHIAASEHRWLLNLPEDPVIVCGDTPR 352 Query 360 LHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGD 419 LHQVV NLL+N R+HT PGT VT L + L V D+GPGIPA Q+E+FERFARGD Sbjct 353 LHQVVANLLSNCRIHTPPGTTVTVTLRSDGNSTYLTVADDGPGIPAGQQNEIFERFARGD 412 Query 420 TSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQ 468 TSRSR+AGSTGLGLAI +AV+KAH+G I V+S G T F + LP G Q Sbjct 413 TSRSRRAGSTGLGLAIAAAVIKAHHGEIRVNSVAGETVFTITLPTAGTQ 461 >gi|159037875|ref|YP_001537128.1| histidine kinase [Salinispora arenicola CNS-205] gi|157916710|gb|ABV98137.1| histidine kinase [Salinispora arenicola CNS-205] Length=477 Score = 411 bits (1056), Expect = 2e-112, Method: Compositional matrix adjust. Identities = 258/478 (54%), Positives = 311/478 (66%), Gaps = 44/478 (9%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFL 60 VGI + T +ALR L ++D QL + PR ++ S P P Sbjct 23 VGIGSITTVALRDLLTDRIDRQL----------RLDAGPR--------GFVPSPPRPAQD 64 Query 61 D---APGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRT------- 110 D + G G V A++ DG ++A + + R ERIA R Sbjct 65 DLQVSRGMEVGSVVALLRDGRV----------AKARIQTAAREGGERIAPERVAALGPLV 114 Query 111 ----PLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVA 166 P T+DL LG YR +A R+G +V L + V T+++M++ V LV Sbjct 115 PNAGPRTVDLGDLGEYRAIARQWRDG-EVTAFALPLAEVQETVMRMVVAQAGVAGTGLVV 173 Query 167 ATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSAL 226 A T G ++++R L PLRRVA TA V +LPLDRGEV LPVRVPE D +P TEVGQ+G+AL Sbjct 174 AGTTGALMVRRTLRPLRRVAATARRVSELPLDRGEVTLPVRVPEADTDPRTEVGQVGAAL 233 Query 227 NRMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHA 285 NRML H+AAAL+ARQASET VRQFVADASHELRTPLAAIRGY E+ +R D P VAHA Sbjct 234 NRMLGHVAAALAARQASETRVRQFVADASHELRTPLAAIRGYAEVARRGRDRVPPDVAHA 293 Query 286 MSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALD 345 + RV SE+ R+T LVEDLLLLARLDSGRPL PVD+S L VDAVSDAHVAGP+H+W LD Sbjct 294 LRRVESESTRMTGLVEDLLLLARLDSGRPLAVQPVDLSALVVDAVSDAHVAGPEHRWQLD 353 Query 346 LPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPA 405 LP + + +PGD ARLHQVV NLLANARVHT GT VTT L+ P VL+V D+GPGIP Sbjct 354 LPEQQIGVPGDPARLHQVVANLLANARVHTPAGTTVTTSLAVEPDAAVLRVADDGPGIPE 413 Query 406 ALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 LQ EVFERFARGD+SRSR GSTGLGLAIV+AVV AH+G ++V S PG T F VRLP Sbjct 414 DLQPEVFERFARGDSSRSRSHGSTGLGLAIVAAVVDAHHGVVSVQSRPGRTVFTVRLP 471 >gi|302530943|ref|ZP_07283285.1| histidine kinase [Streptomyces sp. AA4] gi|302439838|gb|EFL11654.1| histidine kinase [Streptomyces sp. AA4] Length=487 Score = 406 bits (1043), Expect = 5e-111, Method: Compositional matrix adjust. Identities = 249/459 (55%), Positives = 302/459 (66%), Gaps = 14/459 (3%) Query 7 TEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDAPGQP 66 TE+AL LV QLD QL S R + PRPP + P P L GQP Sbjct 39 TELALNSFLVGQLDGQLAAASDRG---FRHGAPRPPI------FGPGKPAPDPLRVLGQP 89 Query 67 AGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDG-LGRYRVL 125 G ++ VV DG G + G ALT L ++ + T++L G LG+YRV+ Sbjct 90 EGTLSLVVHDGAV--NGQVIGPLGLLALTPDQDRVLLVLSPNGQRRTVELPGNLGKYRVV 147 Query 126 AAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRV 185 A S G + V GL M V T+ ++ IFG V + ++ A AG V I+R +APL R+ Sbjct 148 ATYSPRG-EFTVIGLPMNRVSETLWRLGFIFGGVALGGILVAGFAGAVTIRRTMAPLDRL 206 Query 186 AQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQASET 245 A TAS V +LPLDRGEV L RVPE D +P TEVG++GSA+NRML HIA AL+ R ASE+ Sbjct 207 AATASRVSELPLDRGEVALSERVPEVDTDPRTEVGKVGSAINRMLGHIAEALAVRHASES 266 Query 246 CVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERITRLVEDLL 304 VRQFVADASHELRTPLAAIRGY ELT+R + P +A AMSRV SE+ R+T LVEDLL Sbjct 267 RVRQFVADASHELRTPLAAIRGYAELTRRSSEQVPPDIAFAMSRVESESARMTTLVEDLL 326 Query 305 LLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVV 364 LLARLDSGRP+ PVD+SRL DAV+D+HVAGP+H+W L+LP EP+ + GD+ +LHQVV Sbjct 327 LLARLDSGRPVVPEPVDLSRLVADAVADSHVAGPEHKWLLELPGEPIAVLGDSGQLHQVV 386 Query 365 TNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSR 424 NLL NAR HT GT VTT LS L V+D+GPGIP + EVFERFARGD SRSR Sbjct 387 LNLLGNARTHTPAGTTVTTALSARDGWATLSVVDDGPGIPPEILPEVFERFARGDNSRSR 446 Query 425 QAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 AGSTGLGLAIV+AVV AH+G + V+S PG TEF P Sbjct 447 AAGSTGLGLAIVAAVVAAHSGRVMVNSVPGRTEFVASFP 485 >gi|111220169|ref|YP_710963.1| putative sensor histidine kinase [Frankia alni ACN14a] gi|111147701|emb|CAJ59358.1| Putative Sensor histidine kinase [Frankia alni ACN14a] Length=648 Score = 399 bits (1026), Expect = 4e-109, Method: Compositional matrix adjust. Identities = 234/406 (58%), Positives = 287/406 (71%), Gaps = 4/406 (0%) Query 59 FLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDG 118 F P +P G +AA++ DG+ Y+ + S AL++ + + + T L Sbjct 169 FFTGPVEP-GTLAAII-DGSGFYGAYIDTTYSLQALSAGQTATVAAVPRDGGTHTRGLGE 226 Query 119 LGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRA 178 G YR+L++ +G +VTGL M V+AT+ +M I G V + + AA AG VI++ Sbjct 227 AGDYRLLSSTRPDG-TTVVTGLPMKQVNATLTKMAAIAGAVALAGVAAAALAGTVIVRVT 285 Query 179 LAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALS 238 L PLRRVA TAS V ++PLDRGEV L VRVP+ D +P TEVGQ+GSALNRML HI AAL+ Sbjct 286 LRPLRRVAATASRVAEIPLDRGEVALSVRVPDVDTDPRTEVGQVGSALNRMLGHIGAALA 345 Query 239 ARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERIT 297 AR ASET +RQF+AD SHELRTPLAAI GY ELT+R + P V +AMSRV SE+ R+T Sbjct 346 ARHASETRMRQFLADVSHELRTPLAAISGYAELTRRTREPVPPDVTYAMSRVESESARMT 405 Query 298 RLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDA 357 LV DLLLLARLDSGRPLE PVD+SR+ VDAVSDAHVA PDH++ALDLP EPV + GDA Sbjct 406 ALVSDLLLLARLDSGRPLEHEPVDISRMVVDAVSDAHVAAPDHRFALDLPEEPVTVTGDA 465 Query 358 ARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFAR 417 ARLHQV+ NLLANAR HT PGT VT L+ V + ++D+GPGIPA L EVFERFAR Sbjct 466 ARLHQVLANLLANARAHTPPGTRVTASLAVTDDEVTVAIVDDGPGIPADLLPEVFERFAR 525 Query 418 GDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 GD+SRSR AGSTGLGLAIV+AVV+AH G + +S PG T F V LP Sbjct 526 GDSSRSRAAGSTGLGLAIVAAVVEAHQGRVEATSQPGRTAFVVTLP 571 >gi|312200459|ref|YP_004020520.1| integral membrane sensor signal transduction histidine kinase [Frankia sp. EuI1c] gi|311231795|gb|ADP84650.1| integral membrane sensor signal transduction histidine kinase [Frankia sp. EuI1c] Length=616 Score = 399 bits (1025), Expect = 5e-109, Method: Compositional matrix adjust. Identities = 256/500 (52%), Positives = 312/500 (63%), Gaps = 41/500 (8%) Query 3 ITAATEMALRRHLVAQLDNQLGGTSYRSVLMYP-EKMPRPPWRHETHNYI----RSGP-- 55 I T + LR +L+ Q+D +LG R V P + R N GP Sbjct 28 IVGVTALELRSYLIHQVDARLGAVDKRWVKPPPSDANARAGGAFAPGNGTGLGSTGGPDG 87 Query 56 GPR-----------FLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAA-LTSTGRSQLE 103 GP F++ GQ G VAA + G V + G A L ++ ++L Sbjct 88 GPSGVQPWQGTPTDFVNLQGQSTGTVAAHIVGGK-VETAVIPAPGEVAKQLPASEAAKLA 146 Query 104 RIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIA 163 I TP T+ L G YRV A +G +V+GLS+ V+AT+ Q++II G V Sbjct 147 AIPVDDTPRTVTLGSFGEYRVTARLVPDG-TAVVSGLSLSEVNATVDQLIIIAGCVAGCG 205 Query 164 LVAATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLG 223 ++ G V ++R L PLRRVA TA++V +LPLDRG V L VRVP+ D +P TEVGQ+G Sbjct 206 VLLLGVVGAVTVRRTLRPLRRVAATAAQVAELPLDRGAVTLRVRVPDVDTDPRTEVGQVG 265 Query 224 SALNRMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIG-----DD 278 +ALN ML H+ AAL+AR ASET VRQFVADASHELRTPLAAI GY +LT+RIG DD Sbjct 266 AALNHMLGHVGAALAARHASETRVRQFVADASHELRTPLAAISGYAQLTRRIGAQNGFDD 325 Query 279 ------PEAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSD 332 P VA+A+SRV SET+R+T LVEDLLLLARLDSGRPLE G VD+S L VD VSD Sbjct 326 PLRPLVPPDVAYALSRVESETKRMTTLVEDLLLLARLDSGRPLEHGDVDLSLLVVDVVSD 385 Query 333 AHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGP--- 389 AH+A P H+++L LP +PV + GD ARLHQV+ NLLANAR HT GT VT L P Sbjct 386 AHIAAPGHRFSLSLPADPVTVRGDQARLHQVLANLLANARTHTPAGTSVTVALELPPGSG 445 Query 390 ------THVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAH 443 V L VID+GPGIPA L VFERFARGD+SRSR AGSTGLGLAIV+AVV+AH Sbjct 446 TGDSLTGEVRLSVIDDGPGIPADLLPNVFERFARGDSSRSRAAGSTGLGLAIVAAVVEAH 505 Query 444 NGTITVSSSPGYTEFAVRLP 463 G I+V+SSPG T F V LP Sbjct 506 GGRISVTSSPGRTAFTVTLP 525 >gi|145594663|ref|YP_001158960.1| ATPase domain-containing protein [Salinispora tropica CNB-440] gi|145304000|gb|ABP54582.1| ATP-binding region, ATPase domain protein domain protein [Salinispora tropica CNB-440] Length=483 Score = 399 bits (1025), Expect = 6e-109, Method: Compositional matrix adjust. Identities = 253/476 (54%), Positives = 308/476 (65%), Gaps = 40/476 (8%) Query 1 VGITAATEMALRRHLVAQLDNQLG-GTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRF 59 +GI T +ALR L ++D QL RS + P PRP T + ++ Sbjct 29 LGIGGITTVALRDFLTDRIDRQLRLDAGPRSFVPPP---PRP-----TQDDLQV------ 74 Query 60 LDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRT--------- 110 + G G V A + DG V +A + + R ERIA + Sbjct 75 --SRGMEVGSVVAQLRDGQVV----------KARVQNEAREGGERIAPEKVAALGSLVPN 122 Query 111 --PLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAAT 168 P T+DL LG YR +A R+G +V L + V T++++++ V LV A Sbjct 123 TGPHTVDLGDLGEYRAIARQWRDG-EVTAFALPLTEVQETVMRLVVAQAGVAGAGLVVAG 181 Query 169 TAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNR 228 G ++++R L PLRRVA TA+ V +LPLDRGEV LPVRVP D + TEVGQ+GSALNR Sbjct 182 ATGALLVRRTLRPLRRVAATATRVSELPLDRGEVTLPVRVPGADTDTRTEVGQVGSALNR 241 Query 229 MLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMS 287 ML H+AAAL+ARQASET VRQFVADASHELRTPLAAIRGY E+ +R + P VAHA+ Sbjct 242 MLGHVAAALAARQASETRVRQFVADASHELRTPLAAIRGYAEVARRGRNQVPPDVAHALR 301 Query 288 RVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLP 347 RV SE+ R+T LVEDLLLLARLDSGRPL PVD+S L VDAVSDAHVAGP+H+W LDLP Sbjct 302 RVESESTRMTGLVEDLLLLARLDSGRPLAVAPVDLSALVVDAVSDAHVAGPEHRWQLDLP 361 Query 348 PEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAAL 407 + + +PGDAARLHQVV NLL NARVHT GT VTT L+ VL+V D+GPGIP L Sbjct 362 EQQIAVPGDAARLHQVVANLLTNARVHTPAGTTVTTNLAVESDAAVLRVADDGPGIPVEL 421 Query 408 QSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 Q EVFERFAR D+SRSR GSTGLGLAIV+AVV AH+GT++V S PG T F VRLP Sbjct 422 QPEVFERFARADSSRSRSQGSTGLGLAIVAAVVDAHHGTVSVRSRPGRTVFTVRLP 477 >gi|302528955|ref|ZP_07281297.1| phosphate regulon sensor kinase PhoR [Streptomyces sp. AA4] gi|302437850|gb|EFL09666.1| phosphate regulon sensor kinase PhoR [Streptomyces sp. AA4] Length=501 Score = 394 bits (1013), Expect = 1e-107, Method: Compositional matrix adjust. Identities = 248/476 (53%), Positives = 307/476 (65%), Gaps = 20/476 (4%) Query 3 ITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDA 62 I +E ALR L+ Q D QL + R++ P PP + T LDA Sbjct 31 IGVISEFALRAFLLTQTDTQLSAATARALDF--ATHPSPPGENRTP-----------LDA 77 Query 63 PGQPAGMVAAVVS-DGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGR 121 PGQ AG V A S DGT G+L+ G R LTS + L + + P T + LG Sbjct 78 PGQGAGTVTAHFSPDGTNGTGGWLSPHGQRLTLTSEELAALRDLPTNGRPYTRTIGSLGD 137 Query 122 YRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAP 181 YR+ A P +G V++TG+ + + T+L + +I V + A G ++R L P Sbjct 138 YRLTAFPVPDG--VVITGVPLSPMQQTLLTVGLILFGVAAAGVTGAAFLGAFAVRRTLRP 195 Query 182 LRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQ 241 L RVA+TAS V +LPLDRG+V L +RVP D +P TEVGQ+G+ALN ML HI++AL AR Sbjct 196 LDRVAETASRVSELPLDRGDVDLSIRVPAQDTDPRTEVGQVGAALNHMLGHISSALEARH 255 Query 242 ASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERITRLV 300 ASE VR+FVADASHELRTPLAAIRGY EL R P VAH+M+R+ SE +R+T LV Sbjct 256 ASELRVRRFVADASHELRTPLAAIRGYAELAGRSDSHAPPDVAHSMTRIESEADRMTALV 315 Query 301 EDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARL 360 EDLLLLARLD+GRPL+ VD++RL VDAV DAHVAGP H W L +P EP+++ GD RL Sbjct 316 EDLLLLARLDAGRPLDVAEVDLTRLVVDAVGDAHVAGPHHVWQLAMPDEPILVLGDVQRL 375 Query 361 HQVVTNLLANARVHTGPGTIVTTRLS-TGPTHVVLQVIDNGPGIPAALQSEVFERFARGD 419 HQV+ NLLANARVHT PGT V T L+ + V+ V DNGPGIP LQ VFERFARGD Sbjct 376 HQVLANLLANARVHTPPGTTVVTALTRSADGSAVVTVTDNGPGIPPELQPAVFERFARGD 435 Query 420 TSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLDGWQPLESSPR 475 +SRSR AGSTGLGLAI SAV+ AH+G I + S PG TEFAVRLP+ P + +PR Sbjct 436 SSRSRAAGSTGLGLAIASAVLTAHHGAIAMRSRPGQTEFAVRLPI--AVPAQRTPR 489 >gi|50954149|ref|YP_061437.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07] gi|50950631|gb|AAT88332.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07] Length=532 Score = 391 bits (1005), Expect = 1e-106, Method: Compositional matrix adjust. Identities = 235/470 (50%), Positives = 294/470 (63%), Gaps = 25/470 (5%) Query 9 MALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGP-GPRFLDAPGQPA 67 +ALR +L+ +LD QL R P +GP G R + APGQP Sbjct 41 LALRTYLMQRLDGQLTSALSRGAHAADSLFGASP----------TGPEGIRIVAAPGQPT 90 Query 68 GMVAAVVSDGTTVAAGYLTGSGSRAALTSTGR---------SQLERIAGSRTPLTLDL-D 117 G + S + LT + +A QL + P T+D Sbjct 91 GTFGTIRSGNQFLFPVILTDRPAGSADNHPAEPRVVGLIPGDQLRSLPADANPRTIDFGS 150 Query 118 GLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKR 177 G YRV A P NG VI+ GL + +V AT+ ++ + +VT+ +V+A +I+ Sbjct 151 AYGDYRVAAYPLENGDSVII-GLPLSDVQATVGRLTFVIVLVTLAGIVSAFFLASFVIRL 209 Query 178 ALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAAL 237 A+ PL RVA TA +V +PLDRG+V L VRVPE D + TEVG++G+ALNRML H+A+AL Sbjct 210 AMRPLERVAGTAEQVAHMPLDRGDVALSVRVPEEDTDAHTEVGKVGAALNRMLGHVASAL 269 Query 238 SARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERI 296 +ARQASE VRQFVADASHELRTPLA+IRGY ELT+R + P V H++ R+ SE R+ Sbjct 270 TARQASELKVRQFVADASHELRTPLASIRGYAELTRRSPHELPRDVTHSLGRIESEATRM 329 Query 297 TRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGD 356 T LVEDLLLLARLD GR L+R PVD+S L VDA+SDAH AGP H W++ LP EPV + GD Sbjct 330 TSLVEDLLLLARLDEGRELDRDPVDLSLLLVDALSDAHAAGPGHAWSILLPEEPVDVLGD 389 Query 357 AARLHQVVTNLLANARVHTGPGTIVTTRLSTGPT--HVVLQVIDNGPGIPAALQSEVFER 414 A RLHQVV NLLANAR+HT T VT L+ V+ V D+GPGIP LQS +FER Sbjct 390 AQRLHQVVANLLANARLHTPEATKVTASLTVDAEAGQAVVTVADDGPGIPEGLQSTLFER 449 Query 415 FARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 FARGD+SR+R GSTGLGLAIV AVV AH+GT++V S PG T F VRLPL Sbjct 450 FARGDSSRARTTGSTGLGLAIVQAVVVAHDGTVSVQSRPGDTVFTVRLPL 499 >gi|86739036|ref|YP_479436.1| periplasmic sensor signal transduction histidine kinase [Frankia sp. CcI3] gi|86565898|gb|ABD09707.1| periplasmic sensor signal transduction histidine kinase [Frankia sp. CcI3] Length=552 Score = 389 bits (999), Expect = 7e-106, Method: Compositional matrix adjust. Identities = 235/410 (58%), Positives = 287/410 (70%), Gaps = 10/410 (2%) Query 58 RFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLD 117 RF P P + A V DGT A ++ +G LT+ + + I P T Sbjct 118 RFFRGPVDPGTLGAVVGEDGTYGA--FIDTAGEGKELTTAETAVVAGIPAYLRPYTRAFG 175 Query 118 GLGRYRVLAAPSRNGHD--VIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVII 175 G YR+LA R HD ++VTGL M V+AT+ +M +I G+V ++ + AA AG I+ Sbjct 176 DQGDYRLLA---RTTHDDMIVVTGLPMKQVNATLTRMTMIAGVVALVGVAAAAIAGTAIV 232 Query 176 KRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAA 235 + L PLRRVA TAS V +LPLDRGEV L VRVP+ D +P TEVGQ+G+ALNRML HI A Sbjct 233 RVTLRPLRRVAATASRVAELPLDRGEVALSVRVPQVDTDPRTEVGQVGAALNRMLGHIGA 292 Query 236 ALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETE 294 AL+AR ASE +RQF+AD SHELRTPLAAI GY ELT+R + P V +AMSRV SE+ Sbjct 293 ALAARHASEMRMRQFLADVSHELRTPLAAISGYAELTRRTREHVPADVTYAMSRVESESA 352 Query 295 RITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIP 354 R+T LV DLLLLARLDSGR L R PVD+SRL V+AV+DAHVA P H++ALDLP EPV + Sbjct 353 RMTALVSDLLLLARLDSGRDLVREPVDVSRLIVNAVNDAHVAAPGHRFALDLPEEPVTVT 412 Query 355 GDAARLHQVVTNLLANARVHTGPGTIVTTRLS-TGPTHVVLQVIDNGPGIPAALQSEVFE 413 GD ARLHQV+ NLLANAR HT PGT VT L+ +GPT +L V+D+GPGIP L EVF+ Sbjct 413 GDPARLHQVLANLLANARTHTPPGTQVTASLTVSGPT-AILAVVDDGPGIPPDLLPEVFQ 471 Query 414 RFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 RFARGD+SRSR AGSTGLGLAIV+AVV+AH+G + +S PG T F V LP Sbjct 472 RFARGDSSRSRAAGSTGLGLAIVAAVVEAHHGHVRATSEPGRTAFMVELP 521 >gi|302867312|ref|YP_003835949.1| ATP-binding region ATPase domain-containing protein [Micromonospora aurantiaca ATCC 27029] gi|315506282|ref|YP_004085169.1| integral membrane sensor signal transduction histidine kinase [Micromonospora sp. L5] gi|302570171|gb|ADL46373.1| ATP-binding region ATPase domain protein [Micromonospora aurantiaca ATCC 27029] gi|315412901|gb|ADU11018.1| integral membrane sensor signal transduction histidine kinase [Micromonospora sp. L5] Length=510 Score = 389 bits (998), Expect = 8e-106, Method: Compositional matrix adjust. Identities = 253/480 (53%), Positives = 304/480 (64%), Gaps = 31/480 (6%) Query 1 VGITAATEMALRRHLVAQLDNQLGGTSYRSVLMY-----------PEKMPRPPWRHETHN 49 +GI T +ALR L+ Q+DNQL R P++ P PP E Sbjct 39 IGIGGLTTVALRHFLIDQIDNQLTFGDRRPADFERWARRGVDPPRPDQRPTPPDSDEVAP 98 Query 50 YIRSGPGPRFL----DAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERI 105 G P + A +P G V + D V A LT L R+ Sbjct 99 DPPGGFPPGSIAVRVPAAAEPVGRVRSGNGDSEEVPAADLTA--------------LARV 144 Query 106 AGSRTPLTLDLDGLGRYRVLAAPS-RNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIAL 164 P T+ + G YR +A PS R DV+V + + VD T++ ML+ V L Sbjct 145 PVGDRPHTVVVGDRGDYRAIALPSPRGDGDVLVLAIPLAQVDDTVMWMLVAQAGVIGAGL 204 Query 165 VAATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGS 224 V A G++I++ L PL RVA TA+ V +LPLDRGEV L VRVP D +P TEVGQ+G Sbjct 205 VIAGALGLLIVRVTLRPLNRVAATAARVTELPLDRGEVALSVRVPAADTDPRTEVGQVGG 264 Query 225 ALNRMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVA 283 ALNRML H+AAAL ARQASET VRQFVADASHELRTPLAAIRGY E+ +R + P VA Sbjct 265 ALNRMLGHVAAALVARQASETRVRQFVADASHELRTPLAAIRGYAEVARRGRQEVPPDVA 324 Query 284 HAMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWA 343 HA+ RV SE+ R+T LV+DLLLLARLDSGRPL PVD++ +AV+AVSDAHVAGPDH+W Sbjct 325 HALRRVESESTRMTSLVDDLLLLARLDSGRPLAAEPVDLTAMAVNAVSDAHVAGPDHRWQ 384 Query 344 LDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGI 403 LDLP EP+ + GDA RLHQV+ NLLANARVHT GT VT RL+ P V L+V D+GPGI Sbjct 385 LDLPDEPLTVTGDAHRLHQVLANLLANARVHTPAGTTVTVRLAPAPGGVELRVTDDGPGI 444 Query 404 PAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 P LQ EVFERFARGDTSRSR GSTGLGLAIV+AVV+AH+G + V S PG+T F V LP Sbjct 445 PEQLQPEVFERFARGDTSRSRAQGSTGLGLAIVAAVVEAHHGRVDVVSRPGHTAFTVWLP 504 >gi|300788582|ref|YP_003768873.1| two-component system histidine kinase [Amycolatopsis mediterranei U32] gi|299798096|gb|ADJ48471.1| two-component system histidine kinase [Amycolatopsis mediterranei U32] gi|340530189|gb|AEK45394.1| two-component system histidine kinase [Amycolatopsis mediterranei S699] Length=510 Score = 387 bits (995), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 242/461 (53%), Positives = 295/461 (64%), Gaps = 14/461 (3%) Query 7 TEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDAP-GQ 65 +E AL L Q+D QL + RS L++ + RPP GP P P GQ Sbjct 40 SEFALDLFLTRQIDQQLSAAANRS-LVFASNV-RPP---------DGGPPPNLGQHPLGQ 88 Query 66 PAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVL 125 G V+A S V ++ G R L++ ++ + + P TL D LG YR++ Sbjct 89 NVGTVSATFSGRRLVHDDSISEHGGRLELSADQQALMLSVPADGEPHTLSFDDLGEYRLM 148 Query 126 AAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRV 185 A P DV+VTGL M VD T+L + +I V ++ A G ++R L PL RV Sbjct 149 ALPVAGTSDVVVTGLPMKPVDDTLLTVGLILFGVAAAGVLGAALLGAFAVRRTLRPLDRV 208 Query 186 AQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQASET 245 A TA+ V +LPLDRG+V L +RVPE D +P TEVGQ+GSALN ML H+A AL AR SE Sbjct 209 AATAARVTELPLDRGQVALSIRVPEGDTDPRTEVGQVGSALNLMLGHVAQALEARHDSEI 268 Query 246 CVRQFVADASHELRTPLAAIRGYTELTQR-IGDDPEAVAHAMSRVASETERITRLVEDLL 304 VRQFVADASHELRTPLAAIRGY EL R P VAH+M R+ SE R+T LVEDLL Sbjct 269 RVRQFVADASHELRTPLAAIRGYAELAARGSALVPPDVAHSMGRIQSEAVRMTALVEDLL 328 Query 305 LLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVV 364 LLARLD GRPL+ VD++RL DAV DA VAG +H+W L+LPPEPV++ GD RLHQV+ Sbjct 329 LLARLDGGRPLDVREVDLTRLVADAVGDARVAGREHRWRLELPPEPVLVLGDVQRLHQVL 388 Query 365 TNLLANARVHTGPGTIVTTRLS-TGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRS 423 NLLANAR HT PGT V T L+ + VL V D+GPGI L +VFERFARGD+SRS Sbjct 389 ANLLANARTHTPPGTAVVTALARSADGSAVLTVTDDGPGIAPDLLPDVFERFARGDSSRS 448 Query 424 RQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 R AGSTGLG+AI +AVV AH+GTI V S PG TEFAVRLP+ Sbjct 449 RHAGSTGLGMAIAAAVVVAHHGTIEVHSRPGRTEFAVRLPV 489 >gi|88856022|ref|ZP_01130684.1| two-component system, sensor protein [marine actinobacterium PHSC20C1] gi|88814889|gb|EAR24749.1| two-component system, sensor protein [marine actinobacterium PHSC20C1] Length=496 Score = 387 bits (995), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 229/461 (50%), Positives = 295/461 (64%), Gaps = 18/461 (3%) Query 9 MALRRHLVAQLDNQLGGTSYRSVLMYPEKM----PRPPWRHETHNYIRSGPGPRFLDAPG 64 +AL+ L +LD QL S RS +PP P FL PG Sbjct 43 LALQGFLTERLDAQLTAASSRSQGALDGHSRGFGQQPP------------PTGDFLALPG 90 Query 65 QPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDG-LGRYR 123 Q G +A +VS T+ AG L G+ A LT + L + +P+T+DL G LG YR Sbjct 91 QREGTIAGLVSSTGTITAGVLGNRGASAPLTEQQIAVLATLDKLDSPVTVDLGGSLGEYR 150 Query 124 VLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLR 183 V+ + + + ++ L + +V T+LQ+ ++ + ++A+ A AG V ++ AL PL Sbjct 151 VIVSSTPVAGESLIVALPLADVRDTVLQLTLLVVGIGLLAVTIAALAGAVAVRIALRPLE 210 Query 184 RVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQAS 243 RVA TA+ V +L LDRG V L RV DA+P TEVGQ+G+ALNRML+H+A+ALSARQ S Sbjct 211 RVAATATRVTELQLDRGAVALAERVSLDDADPRTEVGQVGAALNRMLEHVASALSARQTS 270 Query 244 ETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERITRLVED 302 E VR FVADASHELRTPLA+IRGY E+T+R G D P VAHA+ R+ +E+ R+T LVE Sbjct 271 ENKVRAFVADASHELRTPLASIRGYAEVTRRGGHDIPADVAHAVGRIEAESVRMTALVES 330 Query 303 LLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQ 362 LLLLARLD +E VD++RL +DAV DAH A PDH W L+L + + GD AR+HQ Sbjct 331 LLLLARLDETAQVELESVDLTRLIIDAVGDAHAASPDHVWELELADHAIAVSGDRARIHQ 390 Query 363 VVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSR 422 V+ NLLANAR+HT GT+VTT L ++++ D GPGIPAALQ VFERF RGD+SR Sbjct 391 VIANLLANARLHTPVGTVVTTCLMREGDSAIIEIRDTGPGIPAALQPTVFERFVRGDSSR 450 Query 423 SRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 SR +GSTGLGLAIV+AVV AH GT +VSS PG T F V LP Sbjct 451 SRASGSTGLGLAIVAAVVGAHGGTASVSSEPGNTVFRVELP 491 >gi|258654799|ref|YP_003203955.1| histidine kinase [Nakamurella multipartita DSM 44233] gi|258558024|gb|ACV80966.1| histidine kinase [Nakamurella multipartita DSM 44233] Length=473 Score = 383 bits (984), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 244/463 (53%), Positives = 300/463 (65%), Gaps = 14/463 (3%) Query 7 TEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDAPGQP 66 TE+ L R+L+ QLD QL + + P + + GPG GQ Sbjct 15 TELFLSRYLMRQLDAQL--QTANEFVFGPVERSAGSLPSCSAASRPGGPG-----GFGQS 67 Query 67 AGMVAAVVSDGTTVAAGYLTGSGSRAA--LTSTGRSQLERIAGSRTPLTLDLDGLGRYRV 124 A + V+ DG V A +T S L++ + L IA + P T+ + GL Sbjct 68 AYSLTGVIVDGQVVNAWTVTPKSSTGCTPLSADADAVLLSIAPAAAPQTVTIPGLDSSYR 127 Query 125 LAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRR 184 + A +RNG V V+GLS V ++ Q+ +I IVT +AL+A A + I++R+L PL R Sbjct 128 VEASTRNGVTV-VSGLSTAQVQGSLFQLAMILLIVTGVALIAGGFAVVWIVRRSLRPLDR 186 Query 185 VAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQASE 244 VA TA +V LPLDRGEV L VRVPE D + TEVGQ+G+ALN+ML H++ AL +RQ SE Sbjct 187 VAATARQVTTLPLDRGEVDLGVRVPEQDTDTRTEVGQVGAALNQMLGHVSGALKSRQESE 246 Query 245 TCVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLL 304 T VRQFVADASHELRTPLA+IRGY EL +R D + V HA+ RV SE+ R++ LV+DLL Sbjct 247 TRVRQFVADASHELRTPLASIRGYAELARRDEHDAQTVGHALRRVESESARMSTLVDDLL 306 Query 305 LLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVV 364 LLARLDSGRPL VDMS L +DAVSDA VAG H+W LDLP EPV + GD ARLHQV+ Sbjct 307 LLARLDSGRPLSADQVDMSMLIIDAVSDARVAGATHRWQLDLPEEPVTVIGDGARLHQVL 366 Query 365 TNLLANARVHTGPGTIVTTRLST----GPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 420 TNLLANAR HT G+ V L T G T V+ V D+GPGIPAALQ E+F RF RGD+ Sbjct 367 TNLLANARTHTPAGSTVRCGLRTEAGPGGTWAVITVTDDGPGIPAALQPEIFNRFVRGDS 426 Query 421 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 SRSR AGSTGLGLAIV+AVV AH GT+TV S PG T F VRLP Sbjct 427 SRSRGAGSTGLGLAIVAAVVGAHRGTVTVQSRPGRTVFTVRLP 469 >gi|170780990|ref|YP_001709322.1| putative two component sensor kinase [Clavibacter michiganensis subsp. sepedonicus] gi|169155558|emb|CAQ00674.1| putative two component sensor kinase [Clavibacter michiganensis subsp. sepedonicus] Length=527 Score = 375 bits (962), Expect = 1e-101, Method: Compositional matrix adjust. Identities = 233/472 (50%), Positives = 296/472 (63%), Gaps = 28/472 (5%) Query 9 MALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPG-PRFLDAPGQPA 67 +ALR L+ Q+D QL T+ RS + + R P + + PG P L A GQ Sbjct 28 LALRTSLMQQVDQQLEATAARS----QDFVDREPGGYGSF------PGAPGGLGAFGQQV 77 Query 68 GMVAAVVSDGTTVAAGYLT---------GSGSRAALTSTGRSQLERIAGSRTPLTLDLDG 118 G ++A + DG V+ GY+ G LT QL+ + P T+DL G Sbjct 78 GTISATIIDGV-VSGGYIADRSAAQGEPGGAGAVELTQRQSEQLQSVPTDGVPRTVDLGG 136 Query 119 -LGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKR 177 LG YR++ S +G IVTGL D + Q++++ +V I L A G +I++R Sbjct 137 ALGSYRLVGQTSSSGA-TIVTGLPTKPADDVVEQLILVITVVAAITLALAALLGTLIVRR 195 Query 178 ALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAAL 237 AL PL RV TA+ V L LDRG+V L RVP D + TEVG++G+ALN +L H+AAAL Sbjct 196 ALRPLDRVVDTATHVAALELDRGDVALEARVPASDTDERTEVGRVGAALNGLLGHVAAAL 255 Query 238 SARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERI 296 S+RQASE VR+FV+DASHELRTPLA+IRGY ELT+R PE V H++SR+ SE+ R+ Sbjct 256 SSRQASEAKVRRFVSDASHELRTPLASIRGYAELTRRGPHQLPEDVTHSLSRIESESVRM 315 Query 297 TRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGD 356 T +VEDLLLLARLD GR LE P+D++R+ +D V DA AGPDH W LDLP V +PGD Sbjct 316 TTIVEDLLLLARLDEGRELESDPIDLTRILLDTVGDASAAGPDHDWDLDLPDGSVTVPGD 375 Query 357 AARLHQVVTNLLANARVHTGPGTIVTTRLST---GP-THVVLQVIDNGPGIPAALQSEVF 412 ARL QVV NLLANAR HT GT V T L+ GP H V++V D+GPGIP ALQ +F Sbjct 376 DARLRQVVVNLLANARTHTPAGTRVVTSLAVEGAGPDAHTVIRVTDDGPGIPPALQETLF 435 Query 413 ERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 ERF RGD SR+R G TGLGLAI A+V AH+G + V S PG T F VRLP+ Sbjct 436 ERFVRGDGSRARTTGGTGLGLAIAQAIVSAHHGAVWVESEPGRTVFGVRLPV 487 >gi|158318232|ref|YP_001510740.1| integral membrane sensor signal transduction histidine kinase [Frankia sp. EAN1pec] gi|158113637|gb|ABW15834.1| integral membrane sensor signal transduction histidine kinase [Frankia sp. EAN1pec] Length=612 Score = 374 bits (961), Expect = 2e-101, Method: Compositional matrix adjust. Identities = 219/375 (59%), Positives = 259/375 (70%), Gaps = 20/375 (5%) Query 120 GRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRAL 179 G YR++A NG V+VTG+ M V AT+ ++ I IV + ++AA AG II+ L Sbjct 202 GDYRLIAHFDPNGQTVLVTGVPMNEVSATLTEVGIAGAIVAALGVLAAGIAGAAIIRVTL 261 Query 180 APLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSA 239 PL RVA TAS V +LPLDRG V L P+ D +P TEVGQ+G+ALNRML HI AA SA Sbjct 262 RPLNRVAATASRVAELPLDRGAVDLMAVAPDVDTDPRTEVGQVGAALNRMLGHIGAAFSA 321 Query 240 RQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERITR 298 R ASET +RQF+ADASHELRTPLAAI GY ELT+R D P VA+AM RV SE+ R+T Sbjct 322 RHASETRMRQFLADASHELRTPLAAISGYAELTRRTRDTVPPDVAYAMGRVESESARMTA 381 Query 299 LVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAA 358 LV DLLLLARLDSGRPL R VD+SRL VDAVSDAHVA P+H++ LDLP PV + GD A Sbjct 382 LVSDLLLLARLDSGRPLVRETVDLSRLVVDAVSDAHVAAPEHRFELDLPSMPVTVAGDPA 441 Query 359 RLHQVVTNLLANARVHTGPGTIVTTRLSTGP-------------------THVVLQVIDN 399 RLHQV+ NLLANAR HT PG+ VT RL+ P VL VID+ Sbjct 442 RLHQVLANLLANARTHTPPGSRVTARLTVEPGPSAPGPSAPVANEPGAGRPSAVLSVIDD 501 Query 400 GPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFA 459 GPGIP AL +VFERFARGD+SRSR AGSTGLGL+IV+AVV+AH+G ++ +S PG T F Sbjct 502 GPGIPDALLPKVFERFARGDSSRSRAAGSTGLGLSIVAAVVEAHHGRVSAASRPGRTAFT 561 Query 460 VRLPLDGWQPLESSP 474 V LPLD P P Sbjct 562 VVLPLDTADPGAPDP 576 >gi|256375857|ref|YP_003099517.1| histidine kinase [Actinosynnema mirum DSM 43827] gi|255920160|gb|ACU35671.1| histidine kinase [Actinosynnema mirum DSM 43827] Length=494 Score = 373 bits (958), Expect = 3e-101, Method: Compositional matrix adjust. Identities = 257/470 (55%), Positives = 301/470 (65%), Gaps = 24/470 (5%) Query 3 ITAATEMALRRHLVAQLDNQLGGTSYRSVLM----YPEKMPRPPWRHETH--NYIRSGPG 56 I T ALR LV +LD QL T+ R+ P M PP R H N GPG Sbjct 38 IGVVTGFALRDFLVQRLDQQLTQTAGRAGFGPGRDDPMFMADPPSRSGEHVLNGPGFGPG 97 Query 57 PRFLDAPGQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDL 116 + G G V A D AG L +A LT+ L + P T++L Sbjct 98 TLVFETLG---GTVEANRVD----TAGTLETIADQATLTT-----LSSVPADGRPRTVEL 145 Query 117 DGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIK 176 LG YRV++A R G +VTGL + V +T+L+M +I G V + L+ AG +II+ Sbjct 146 GALGGYRVVSAQFRTG--TVVTGLPLSEVSSTVLRMGLILGGVALGGLITVGLAGALIIR 203 Query 177 RALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAA 236 R L PL RVA TA V +LPL GEV L RVP DA P TEVGQ+G ALNRML H+ A Sbjct 204 RTLEPLERVAATAGRVAELPLHEGEVALAERVPAADATPDTEVGQVGLALNRMLGHVGEA 263 Query 237 LSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGD--DPEAVAHAMSRVASETE 294 LSAR ASET VRQFVADASHELRTPLAAIRGY ELT+R + PE +AHAM RV SE Sbjct 264 LSARHASETRVRQFVADASHELRTPLAAIRGYAELTRRSREVVSPE-IAHAMGRVESEAV 322 Query 295 RITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIP 354 R+T LVEDLLLLARLD+GRPLE G VD+SRL VD+VSDA +AG +H W L LPPE V + Sbjct 323 RMTSLVEDLLLLARLDAGRPLELGEVDLSRLVVDSVSDARIAGREHDWRLALPPEAVTVR 382 Query 355 GDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVV-LQVIDNGPGIPAALQSEVFE 413 GDA R+ QV+ NLL+NAR HT PGT VTT L+ G V L V D+GPGIP ALQ EVFE Sbjct 383 GDADRVRQVLANLLSNARAHTPPGTTVTTVLNPGRAGWVDLVVADDGPGIPEALQPEVFE 442 Query 414 RFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 RFARGD+SRSR AGSTGLGL+IV+AVV AH G++ V S PG T F V LP Sbjct 443 RFARGDSSRSRAAGSTGLGLSIVAAVVSAHGGSVRVDSRPGATRFTVSLP 492 >gi|148273949|ref|YP_001223510.1| putative two-component system, sensor kinase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] gi|147831879|emb|CAN02849.1| putative two-component system, sensor kinase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] Length=558 Score = 361 bits (927), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 229/473 (49%), Positives = 292/473 (62%), Gaps = 29/473 (6%) Query 9 MALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPG--PRFLDAPGQP 66 +ALR LV ++D QL T+ RS + + S PG P L A GQ Sbjct 58 LALRASLVQEVDQQLQATAARSSNLIDRDA----------DQYGSFPGAPPGGLGAFGQQ 107 Query 67 AGMVAAVVSDGTTVAAGYLT---------GSGSRAALTSTGRSQLERIAGSRTPLTLDLD 117 G ++A + DG V+ GY+ G LT QL+ + P T+DL Sbjct 108 VGTISATIVDGV-VSGGYIADRDAAEGEPGGAGAVELTQVQSQQLQSVPTDGIPRTVDLG 166 Query 118 G-LGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIK 176 G LGRYR++ + G +VTGL M D + Q++++ +V + L A G VI++ Sbjct 167 GALGRYRLVGDTAATGA-TLVTGLPMKPADDVVEQLIVVISVVAALTLALAAVLGAVIVR 225 Query 177 RALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAA 236 RAL PL RV TA+ V L LDRG+V L RVP D + TEVG++G+ALN +L H+AAA Sbjct 226 RALRPLDRVVDTATHVAALELDRGDVALEARVPASDTDERTEVGRVGAALNGLLGHVAAA 285 Query 237 LSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETER 295 LS+RQASE VR+FV+DASHELRTPLA+IRGY ELT+R PE V H++SR+ SE+ R Sbjct 286 LSSRQASEAKVRRFVSDASHELRTPLASIRGYAELTRRGPHQLPEDVTHSLSRIESESVR 345 Query 296 ITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPG 355 +T +VEDLLLLARLD GR LE PVD++R+ +D V DA AGPDH W LDLP + V +PG Sbjct 346 MTTIVEDLLLLARLDEGRELESDPVDLTRILLDTVGDASAAGPDHDWDLDLPDDSVSVPG 405 Query 356 DAARLHQVVTNLLANARVHTGPGTIVTTRLST----GPTHVVLQVIDNGPGIPAALQSEV 411 D ARL QVV NLLANAR HT GT V L+ H V++V D+GPGIP LQ+ + Sbjct 406 DDARLRQVVVNLLANARTHTPAGTRVVASLAVEGAGSDAHAVIRVTDDGPGIPPELQASL 465 Query 412 FERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 FERF RGD SR+R G TGLGLAI A+V AH+G + V S PG T F VRLP+ Sbjct 466 FERFVRGDGSRARSTGGTGLGLAIAQAIVSAHHGAVWVESEPGRTVFGVRLPV 518 >gi|328883820|emb|CCA57059.1| Two-component system, sensor protein [Streptomyces venezuelae ATCC 10712] Length=519 Score = 360 bits (925), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 236/474 (50%), Positives = 297/474 (63%), Gaps = 25/474 (5%) Query 3 ITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDA 62 I T +A R +L + D ++ S+ + P +P P R T RF+ Sbjct 39 IGTVTTIAFRSYLYDRADEEVRAVSHWAA-GPPAALPEP-GRAGTDQL-------RFVVG 89 Query 63 PGQPAGMVAAVVSDGTTVAAGY--------LTGSGSR-AALTSTGRSQLERIAGSRTPLT 113 PG G + AV++ G AAGY + G R L R+ L + P T Sbjct 90 PGAKTGTLGAVLTGGEVTAAGYSAEAEDSGVYGPPERIKPLDDAQRAALAAVPRDGRPHT 149 Query 114 LDL-DGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGI 172 +DL GLG YRV A + G +TG+ + V+ + ++++ VT L AA+ AG Sbjct 150 VDLPGGLGSYRV--AYAEGGKGTFLTGIPLAEVEDALSTLILVELSVTGAGLFAASLAGT 207 Query 173 VIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDH 232 V+++ AL PLRRVA TA +V LPL GEV L RVPEP+A+P TEVGQ+G+A+NRMLDH Sbjct 208 VLVRVALRPLRRVAVTARQVAQLPLHSGEVALHQRVPEPEADPRTEVGQVGAAINRMLDH 267 Query 233 IAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD--PEAVAHAMSRVA 290 + +AL ARQ SET VRQFVADASHELRTPLA+IRGY ELT+R G++ P+ HA+ R+ Sbjct 268 VHSALDARQQSETRVRQFVADASHELRTPLASIRGYAELTRRGGEECGPD-TRHALGRIE 326 Query 291 SETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEP 350 SE R+T LVEDLLLLARLD+GRPL P D+ L VDAVSDA AGP H W+L+LP + Sbjct 327 SEATRMTGLVEDLLLLARLDAGRPLSYEPTDLLPLVVDAVSDARAAGPGHHWSLELPEDG 386 Query 351 V-VIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQS 409 + D AR+ QV+ NLLANAR HT PGT VT R+ T V++Q+ D+GPGIP L Sbjct 387 APPVRADGARIQQVLVNLLANARTHTPPGTKVTARVRTDGAGVIVQIEDDGPGIPPELLP 446 Query 410 EVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 VFERFARGD SRSR AGSTGLGLAIV AVV AH G + V S+PG T F VRLP Sbjct 447 AVFERFARGDASRSRNAGSTGLGLAIVRAVVGAHGGDVDVESAPGRTVFTVRLP 500 >gi|152966981|ref|YP_001362765.1| integral membrane sensor signal transduction histidine kinase [Kineococcus radiotolerans SRS30216] gi|151361498|gb|ABS04501.1| integral membrane sensor signal transduction histidine kinase [Kineococcus radiotolerans SRS30216] Length=509 Score = 360 bits (924), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 207/356 (59%), Positives = 254/356 (72%), Gaps = 8/356 (2%) Query 113 TLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGI 172 T+DL+GLGRYRV++ +G V+G+ + +VD T+L ++ + + + A AG Sbjct 155 TVDLEGLGRYRVVSTTLPDGSRQ-VSGVPLADVDRTLLTVVGVEVAAILGGVAVAAGAGS 213 Query 173 VIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDH 232 V+++R L PL+RVA TA+ V +L LDRGEV L +RVP DA+ STEVG++ ALNRMLD+ Sbjct 214 VLVRRDLLPLQRVANTAARVSELELDRGEVDLSLRVP--DADGSTEVGKVALALNRMLDN 271 Query 233 IAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQRI-----GDDPEAVAHAMS 287 + +AL AR ASE VRQFVADASHELRTPLAAIRGY+ELT+R G P V HAM Sbjct 272 VGSALEARHASEQRVRQFVADASHELRTPLAAIRGYSELTRRSRDVTGGQVPADVLHAMG 331 Query 288 RVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLP 347 RV SE R+T LVEDLLLLARLDSGRPL+RGPVD++ +DAVSDA VAG DH+W LDLP Sbjct 332 RVESEALRMTGLVEDLLLLARLDSGRPLDRGPVDLTMTVLDAVSDAQVAGRDHRWQLDLP 391 Query 348 PEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAAL 407 E V + GDA RLHQV+ NLLANAR HT PGT VT + + V+D+GPGI + Sbjct 392 EEAVEVVGDAGRLHQVLANLLANARTHTPPGTTVTVGIVPDGAVAHVDVVDDGPGIAPEV 451 Query 408 QSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 VFERF R D+SRSR AGSTGLGLAIV AVV +H+GT+TV S PG T F V LP Sbjct 452 LPRVFERFVRADSSRSRVAGSTGLGLAIVQAVVASHHGTVTVDSRPGRTAFRVTLP 507 >gi|297158649|gb|ADI08361.1| putative two component system sensor kinase [Streptomyces bingchenggensis BCW-1] Length=575 Score = 359 bits (922), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 249/513 (49%), Positives = 304/513 (60%), Gaps = 67/513 (13%) Query 3 ITAATEMALRRHLVAQLDNQLGGTSYRSVLMYPE----KMPRP--PWRHETHNYIRSGPG 56 I T +AL +L Q+D QL G + R + P K PRP WR + + + Sbjct 44 IGTVTTIALHTYLYDQVDKQLSGVATR--IAGPPFDEVKGPRPGGQWREDIRDVV----- 96 Query 57 PRFLDAPGQPAGMVAA-----VVSDGTTVAAGYLTGSG----SRAALTSTGRSQLERIAG 107 PGQP G VAA V+S+G ++ + + +G S + LT+ L + Sbjct 97 ----AGPGQPMGTVAAEAEGGVLSEGA-ISRQHESSTGEPKISGSYLTAAQLKALSEVPQ 151 Query 108 SRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAA 167 + T+D+ G G YRV GH V G+S T+ +++ VT LVAA Sbjct 152 DGSEHTVDIPGKGEYRVKYVV--GGHGDFVVGISTAEAQNTVDTLILAEISVTAAGLVAA 209 Query 168 TTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALN 227 AG V++ +L PLRRVA TA+ V +LPL GEV L RVP +A+P TEVGQ+G+ALN Sbjct 210 GIAGAVMVGISLRPLRRVAATATRVSELPLHSGEVALHERVPMSEADPRTEVGQVGAALN 269 Query 228 RMLDHIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQR----IGDDPEAVA 283 RML H+ +AL+ARQ SET VRQFVADASHELRTPLA+IRGY ELT+R IG D Sbjct 270 RMLGHVESALAARQESETRVRQFVADASHELRTPLASIRGYAELTRRGREEIGPDTR--- 326 Query 284 HAMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWA 343 HA+ RV SE R+T LVEDLLLLARLD+GRP+ER VD+S + VDAVSDA AGPDH+W Sbjct 327 HALGRVESEAARMTGLVEDLLLLARLDAGRPVERAEVDLSPVVVDAVSDARAAGPDHKWR 386 Query 344 LDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTR-LSTGPTH----------- 391 L+LP +P V+ GD ARL QV+ NLLANAR HT PGT VT R L GP Sbjct 387 LELPDDPAVVYGDDARLRQVLVNLLANARTHTPPGTTVTARVLWRGPYRAGHGAPYPAAP 446 Query 392 -------------------VVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLG 432 V L+V D+GPGIP L VFERFARGD SRSR AGSTGLG Sbjct 447 YPAPYPAPYSGFSGYSAPCVSLEVEDDGPGIPPHLLPHVFERFARGDASRSRAAGSTGLG 506 Query 433 LAIVSAVVKAHNGTITVSSSPGYTEFAVRLPLD 465 LAIV AVV AH G +TV S PG T F V LP+D Sbjct 507 LAIVHAVVTAHGGQVTVDSVPGRTVFGVHLPVD 539 >gi|288918082|ref|ZP_06412439.1| histidine kinase [Frankia sp. EUN1f] gi|288350464|gb|EFC84684.1| histidine kinase [Frankia sp. EUN1f] Length=721 Score = 359 bits (921), Expect = 7e-97, Method: Compositional matrix adjust. Identities = 240/480 (50%), Positives = 296/480 (62%), Gaps = 37/480 (7%) Query 4 TAATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDAP 63 ++ +E+++ L LD Q+ GT +V+ ++P R G GP Sbjct 125 SSTSELSVSDQLTLFLDRQVSGT-LGAVVELRGQVP-----------FRPGAGPE----- 167 Query 64 GQPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYR 123 P ++ V + +L+ GS ALT + + +I T + G G YR Sbjct 168 -DPPAALSPNVDELVDKVTAWLSDDGSVIALTGADATTVAQIPLDGVAHTRTIGGHGDYR 226 Query 124 VLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLR 183 + A S +G ++VTGL M VDAT+ + I V ++AA AG I++R L PL Sbjct 227 LTARLSGDGSRILVTGLPMNEVDATLTRTAAIGAAVAAFGVLAAAIAGGAIVRRTLRPLS 286 Query 184 RVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQAS 243 RVA TA+ V +LPL RG V LP P+ D +P TEVGQ+G+AL RML HI A AR AS Sbjct 287 RVAATAARVAELPLHRGAVDLPTLGPDVDTDPRTEVGQVGAALGRMLGHIGDAFDARHAS 346 Query 244 ETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERITRLVED 302 ET +RQF+ADASHELRTPLAAI GY ELT+R P V +AM RV SE+ R+T LV D Sbjct 347 ETRMRQFLADASHELRTPLAAISGYAELTRRTKATVPPDVVYAMGRVESESARMTALVSD 406 Query 303 LLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQ 362 LLLLARLDSGRPL R VD+SRL VDAVSDAHVA P H++ LDLP EPV GD ARLHQ Sbjct 407 LLLLARLDSGRPLVRETVDLSRLVVDAVSDAHVAAPTHRFELDLPSEPVTTTGDPARLHQ 466 Query 363 VVTNLLANARVHTGPGTIVTTRLST----------------GPT--HVVLQVIDNGPGIP 404 V+TNLLANAR HT PGT VT RL+T GP VLQVID+GPGIP Sbjct 467 VLTNLLANARTHTPPGTRVTARLTTQARPAPPGSFAPPGMPGPLVWCAVLQVIDDGPGIP 526 Query 405 AALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 L +VFERFARGD+SRSR AGSTGLGL+IVSAVV+AH+G + V+S PG T F V LP+ Sbjct 527 PELLPKVFERFARGDSSRSRAAGSTGLGLSIVSAVVEAHHGRVEVASRPGQTVFTVLLPV 586 >gi|336116251|ref|YP_004571017.1| two-component system histidine kinase [Microlunatus phosphovorus NM-1] gi|334684029|dbj|BAK33614.1| two-component system histidine kinase [Microlunatus phosphovorus NM-1] Length=502 Score = 358 bits (920), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 237/470 (51%), Positives = 303/470 (65%), Gaps = 27/470 (5%) Query 7 TEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPG--PRFLDAPG 64 T +A R L +QLD Q+ R +M + GPG PR ++ PG Sbjct 44 TALATRTLLTSQLDKQVLAAKAR--IMQGDI-----------GLANGGPGQAPRGIELPG 90 Query 65 QPAGMVAAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRT---PLTLDLDGLGR 121 Q G ++ + ++G L SG RA T T E +AG T P+T+D+ LGR Sbjct 91 QAVGTLSMIYAEGQAPRGSVLLESGRRAKPTWTSDQTAELLAGLSTTPGPITIDIPELGR 150 Query 122 YRVLAAPSRNGHDVIV-TGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALA 180 YR ++ +G VIV GL + VD+ + ++ + I++++A+ AA AG +++R+L Sbjct 151 YRYVSWSPGDG--VIVGVGLPLTGVDSALANLITVEIILSIVAVGAAALAGRALVERSLR 208 Query 181 PLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSAR 240 PL RVA TA +V LPLDRGEV L VRVP D +P +EVG++G ALN ML+++ AL+AR Sbjct 209 PLNRVAATAQQVSQLPLDRGEVALAVRVPPTDTDPQSEVGRVGLALNHMLNNVEDALAAR 268 Query 241 QASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERITRL 299 QASET VRQFVADASHELR PLAAIRGY ELTQR G+ P A+AMSRV SE ER++ L Sbjct 269 QASETKVRQFVADASHELRNPLAAIRGYAELTQRSGEAIPPDAAYAMSRVESEAERMSTL 328 Query 300 VEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAAR 359 VEDLLLLARLD+G L+ P D++ L +DAVSDA VAGPDH W+L LP E V + D+ R Sbjct 329 VEDLLLLARLDAGPALDIQPTDLNVLLIDAVSDARVAGPDHHWSLALPEEIVEVQADSYR 388 Query 360 LHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGD 419 LHQVVTNLLANAR HT GT V L T H V+ V D+GPGI + + VFERF R D Sbjct 389 LHQVVTNLLANARTHTPAGTRVQVSLGTTADHAVITVADDGPGIAPDMLNRVFERFTRAD 448 Query 420 TSRSRQA-----GSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLPL 464 +SR+R A GSTGLGLAIV+AVV+AH+GT++V S PG T F V LPL Sbjct 449 SSRARTAGAAPGGSTGLGLAIVTAVVEAHHGTVSVQSQPGDTRFVVSLPL 498 >gi|119962003|ref|YP_946601.1| signal transduction histidine kinase [Arthrobacter aurescens TC1] gi|119948862|gb|ABM07773.1| putative signal transduction histidine kinase [Arthrobacter aurescens TC1] Length=498 Score = 357 bits (917), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 204/447 (46%), Positives = 281/447 (63%), Gaps = 13/447 (2%) Query 18 QLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDAPGQPAGMVAAVVSDG 77 QLD QL S R+ RPP N+ P L+A GQ AG + A + Sbjct 57 QLDRQLEQASSRA-----NDFGRPP-----SNFPSPSGRPDPLEARGQAAGTLNARIDGS 106 Query 78 TTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIV 137 T ++G + G R +L++ L + P+ L G YR++A + G DVIV Sbjct 107 TVRSSGLIDAQGHRVSLSADDEQVLLSLPRDNGPVDRSLSN-GDYRLVAVETAYG-DVIV 164 Query 138 TGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASEVVDLPL 197 TGL + + + ++ +V++ LV AG VII+R + PL ++++ A++V LPL Sbjct 165 TGLPLADKQSAEASLVWTMVLVSLGGLVVIGLAGTVIIRRTMRPLEQLSEVATKVSRLPL 224 Query 198 DRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQASETCVRQFVADASHE 257 D GEV L VRVP ++P TEVG +G ALN+ML+++++AL ARQ SET VRQFVADASHE Sbjct 225 DAGEVALAVRVPPSASHPGTEVGSVGYALNQMLNNVSSALEARQESETKVRQFVADASHE 284 Query 258 LRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLER 317 LRTPL AIRGYTEL + + E +++RV S++ER+T LVEDLLLLARLD G+P++ Sbjct 285 LRTPLTAIRGYTELLRMTENFTEDGRKSLARVQSQSERMTTLVEDLLLLARLDEGQPVKV 344 Query 318 GPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGP 377 VD+++L ++ VSD V PDH W L LP EP+ + GDA +LHQV+ NLL+NAR HT P Sbjct 345 EDVDLTQLVIETVSDEKVMAPDHIWQLQLPDEPITVRGDATQLHQVLANLLSNARKHTDP 404 Query 378 G-TIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIV 436 G T+VT + + V+ V DNGPGIP Q +F RFAR D +RS G++GLGL+IV Sbjct 405 GTTVVTGVMLSADGSAVVSVTDNGPGIPEDFQGRIFSRFARADAARSGSEGTSGLGLSIV 464 Query 437 SAVVKAHNGTITVSSSPGYTEFAVRLP 463 ++V AH G++ V+S PG TEFA+RLP Sbjct 465 ESIVSAHGGSVEVTSRPGRTEFALRLP 491 >gi|317126454|ref|YP_004100566.1| integral membrane sensor signal transduction histidine kinase [Intrasporangium calvum DSM 43043] gi|315590542|gb|ADU49839.1| integral membrane sensor signal transduction histidine kinase [Intrasporangium calvum DSM 43043] Length=508 Score = 357 bits (916), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 233/466 (50%), Positives = 293/466 (63%), Gaps = 47/466 (10%) Query 13 RHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDA---PGQPAGM 69 +HLVAQ+D QL R+ + P M ++ R GPG L A PG G Sbjct 73 QHLVAQVDEQL-----RASMHAPRMM--------DNDMRRGGPGADSLVAQFTPGSALGW 119 Query 70 VAAVVSD----GTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDG-LGRYRV 124 V + D GT +AA GS TP T+DL G LGR+R+ Sbjct 120 VLSPERDTKLGGTALAAITAADLGS-------------------TPRTVDLGGALGRFRM 160 Query 125 LA--APSRNGHDVI----VTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRA 178 +A A R+G+D++ V GLSM DAT+ +M++I ++ G I++R+ Sbjct 161 VAEQANLRSGNDLVPVTLVVGLSMAPTDATLARMVLIAASSVAAGVLLVGGLGTWIVRRS 220 Query 179 LAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALS 238 L PLRRVA TA+ V +PL +G+V+L RV D + TEVGQ+G+A N MLDH+ AL+ Sbjct 221 LEPLRRVADTATRVSRMPLHQGQVQLVERVAPEDTDTRTEVGQVGAAFNEMLDHVDEALN 280 Query 239 ARQASETCVRQFVADASHELRTPLAAIRGYTELTQRIGDD-PEAVAHAMSRVASETERIT 297 AR SE VRQFVADASHELRTPLA+I+GY EL++R D PE+V HAMSR+ SE R+ Sbjct 281 ARHRSEQRVRQFVADASHELRTPLASIKGYAELSRREPDALPESVTHAMSRIESEAGRMG 340 Query 298 RLVEDLLLLARLDSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDA 357 LVEDLLLLARLD+GRPL PVD+S L V+AVSDAH A PDH+W LDLPP+PV + GD+ Sbjct 341 SLVEDLLLLARLDAGRPLASEPVDLSMLVVNAVSDAHAAAPDHRWDLDLPPDPVEVRGDS 400 Query 358 ARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFAR 417 ARLHQVV NLLANAR HT GT VTT + V + V D+GPG+P LQ VFERFAR Sbjct 401 ARLHQVVANLLANARTHTPAGTRVTTAVRPEGDRVRISVHDDGPGVPIDLQPNVFERFAR 460 Query 418 GDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 463 GD +R+R GSTGLGL+IV+AV +AH G + +SS PG T FA LP Sbjct 461 GDNARTRAGGSTGLGLSIVAAVTRAHGGRVELSSRPGDTTFAFVLP 506 Lambda K H 0.317 0.133 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1009956255448 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40