BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3765c

Length=234
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|254366310|ref|ZP_04982354.1|  hypothetical two component trans...   469    1e-130
gi|308232561|ref|ZP_07664116.1|  two component system transcripti...   469    2e-130
gi|15610901|ref|NP_218282.1|  two component transcriptional regul...   468    2e-130
gi|289556030|ref|ZP_06445240.1|  two component system transcripti...   468    3e-130
gi|15843385|ref|NP_338422.1|  DNA-binding response regulator [Myc...   467    7e-130
gi|41406357|ref|NP_959193.1|  hypothetical protein MAP0259 [Mycob...   422    1e-116
gi|183985285|ref|YP_001853576.1|  two-component transcriptional r...   422    2e-116
gi|254773313|ref|ZP_05214829.1|  DNA-binding response regulator [...   422    2e-116
gi|254822466|ref|ZP_05227467.1|  DNA-binding response regulator [...   421    5e-116
gi|342860017|ref|ZP_08716669.1|  DNA-binding response regulator [...   421    5e-116
gi|296166889|ref|ZP_06849306.1|  DNA-binding response regulator [...   419    2e-115
gi|336460748|gb|EGO39636.1|  response regulator with CheY-like re...   417    9e-115
gi|118619527|ref|YP_907859.1|  two component transcriptional regu...   417    9e-115
gi|240168529|ref|ZP_04747188.1|  two-component transcriptional re...   403    1e-110
gi|118470471|ref|YP_889241.1|  DNA-binding response regulator [My...   390    8e-107
gi|120405382|ref|YP_955211.1|  two component transcriptional regu...   385    3e-105
gi|108800890|ref|YP_641087.1|  two component transcriptional regu...   380    6e-104
gi|333992682|ref|YP_004525296.1|  two-component transcriptional r...   377    1e-102
gi|145222854|ref|YP_001133532.1|  two component transcriptional r...   373    1e-101
gi|331698780|ref|YP_004335019.1|  winged helix family two compone...   348    4e-94 
gi|297200795|ref|ZP_06918192.1|  phosphate regulon transcriptiona...   344    5e-93 
gi|302552564|ref|ZP_07304906.1|  phosphate regulon transcriptiona...   343    1e-92 
gi|29830741|ref|NP_825375.1|  two-component system response regul...   343    1e-92 
gi|324999382|ref|ZP_08120494.1|  two component transcriptional re...   343    2e-92 
gi|296394075|ref|YP_003658959.1|  transcriptional regulator [Segn...   343    2e-92 
gi|302544103|ref|ZP_07296445.1|  DNA-binding response regulator T...   342    2e-92 
gi|294630229|ref|ZP_06708789.1|  DNA-binding response regulator T...   341    5e-92 
gi|290959131|ref|YP_003490313.1|  two component system response r...   341    5e-92 
gi|145594662|ref|YP_001158959.1|  response regulator receiver [Sa...   341    6e-92 
gi|297625540|ref|YP_003687303.1|  two component system response r...   340    8e-92 
gi|302559780|ref|ZP_07312122.1|  DNA-binding response regulator T...   340    9e-92 
gi|21222423|ref|NP_628202.1|  two component system response regul...   340    1e-91 
gi|289770395|ref|ZP_06529773.1|  two component system response re...   340    1e-91 
gi|119717917|ref|YP_924882.1|  response regulator receiver [Nocar...   340    1e-91 
gi|269796544|ref|YP_003315999.1|  CheY-like receiver domain/winge...   339    2e-91 
gi|302867311|ref|YP_003835948.1|  response regulator receiver [Mi...   338    3e-91 
gi|300790732|ref|YP_003771023.1|  two-component system response r...   338    3e-91 
gi|291438629|ref|ZP_06578019.1|  two-component system response re...   338    4e-91 
gi|340532422|gb|AEK47627.1|  two-component system response regula...   338    4e-91 
gi|345016321|ref|YP_004818675.1|  winged helix family two compone...   338    5e-91 
gi|336116252|ref|YP_004571018.1|  two-component system response r...   338    5e-91 
gi|330468634|ref|YP_004406377.1|  two component transcriptional r...   338    5e-91 
gi|297193412|ref|ZP_06910810.1|  two-component system response re...   337    6e-91 
gi|111220170|ref|YP_710964.1|  putative two-component system resp...   337    6e-91 
gi|326333582|ref|ZP_08199821.1|  DNA-binding response regulator T...   337    7e-91 
gi|345000963|ref|YP_004803817.1|  winged helix family two compone...   337    9e-91 
gi|297158650|gb|ADI08362.1|  two-component system response regula...   337    1e-90 
gi|159037874|ref|YP_001537127.1|  two component transcriptional r...   337    1e-90 
gi|329938744|ref|ZP_08288140.1|  two component system response re...   337    1e-90 
gi|328883819|emb|CCA57058.1|  putative two-component system respo...   337    1e-90 


>gi|254366310|ref|ZP_04982354.1| hypothetical two component transcriptional regulatory protein 
[Mycobacterium tuberculosis str. Haarlem]
 gi|308406239|ref|ZP_07669548.1| two component system transcriptional regulator [Mycobacterium 
tuberculosis SUMu012]
 gi|134151822|gb|EBA43867.1| hypothetical two component transcriptional regulatory protein 
[Mycobacterium tuberculosis str. Haarlem]
 gi|308364040|gb|EFP52891.1| two component system transcriptional regulator [Mycobacterium 
tuberculosis SUMu012]
 gi|323717630|gb|EGB26832.1| two component system transcriptional regulator [Mycobacterium 
tuberculosis CDC1551A]
 gi|339296572|gb|AEJ48683.1| DNA-binding response regulator [Mycobacterium tuberculosis CCDC5079]
 gi|339300171|gb|AEJ52281.1| DNA-binding response regulator [Mycobacterium tuberculosis CCDC5180]
Length=246

 Score =  469 bits (1207),  Expect = 1e-130, Method: Compositional matrix adjust.
 Identities = 234/234 (100%), Positives = 234/234 (100%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV
Sbjct  13   MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  72

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  73   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  132

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL
Sbjct  133  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  192

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  193  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  246


>gi|308232561|ref|ZP_07664116.1| two component system transcriptional regulator [Mycobacterium 
tuberculosis SUMu001]
 gi|308369225|ref|ZP_07416994.2| two component system transcriptional regulator [Mycobacterium 
tuberculosis SUMu002]
 gi|308371446|ref|ZP_07667165.1| two component system transcriptional regulator [Mycobacterium 
tuberculosis SUMu003]
 19 more sequence titles
 Length=252

 Score =  469 bits (1206),  Expect = 2e-130, Method: Compositional matrix adjust.
 Identities = 234/234 (100%), Positives = 234/234 (100%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV
Sbjct  19   MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  78

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  79   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  138

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL
Sbjct  139  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  198

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  199  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  252


>gi|15610901|ref|NP_218282.1| two component transcriptional regulatory protein [Mycobacterium 
tuberculosis H37Rv]
 gi|31794935|ref|NP_857428.1| putative two component transcriptional regulatory protein [Mycobacterium 
bovis AF2122/97]
 gi|121639679|ref|YP_979903.1| putative two component transcriptional regulatory protein [Mycobacterium 
bovis BCG str. Pasteur 1173P2]
 39 more sequence titles
 Length=234

 Score =  468 bits (1205),  Expect = 2e-130, Method: Compositional matrix adjust.
 Identities = 234/234 (100%), Positives = 234/234 (100%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV
Sbjct  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL
Sbjct  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234


>gi|289556030|ref|ZP_06445240.1| two component system transcriptional regulator [Mycobacterium 
tuberculosis KZN 605]
 gi|289440662|gb|EFD23155.1| two component system transcriptional regulator [Mycobacterium 
tuberculosis KZN 605]
Length=272

 Score =  468 bits (1205),  Expect = 3e-130, Method: Compositional matrix adjust.
 Identities = 234/234 (100%), Positives = 234/234 (100%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV
Sbjct  39   MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  98

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  99   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  158

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL
Sbjct  159  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  218

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  219  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  272


>gi|15843385|ref|NP_338422.1| DNA-binding response regulator [Mycobacterium tuberculosis CDC1551]
 gi|148824970|ref|YP_001289724.1| two component transcriptional regulatory protein [Mycobacterium 
tuberculosis F11]
 gi|253800812|ref|YP_003033813.1| two component system transcriptional regulator [Mycobacterium 
tuberculosis KZN 1435]
 8 more sequence titles
 Length=286

 Score =  467 bits (1201),  Expect = 7e-130, Method: Compositional matrix adjust.
 Identities = 234/234 (100%), Positives = 234/234 (100%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV
Sbjct  53   MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  112

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  113  MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  172

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL
Sbjct  173  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  232

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  233  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  286


>gi|41406357|ref|NP_959193.1| hypothetical protein MAP0259 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118466148|ref|YP_879593.1| DNA-binding response regulator [Mycobacterium avium 104]
 gi|41394705|gb|AAS02576.1| hypothetical protein MAP_0259 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118167435|gb|ABK68332.1| DNA-binding response regulator [Mycobacterium avium 104]
Length=246

 Score =  422 bits (1086),  Expect = 1e-116, Method: Compositional matrix adjust.
 Identities = 220/234 (95%), Positives = 223/234 (96%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADG P+ VLVVDDE VLAEMVSMALRYEGWNI TA DG+SAIAAAR QRPDVVVLDV
Sbjct  13   MCRADGNPINVLVVDDEAVLAEMVSMALRYEGWNIATASDGASAIAAARNQRPDVVVLDV  72

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLR ENP LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  73   MLPDMSGLDVLHKLREENPQLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  132

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  133  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVTRAGEPISLTSTEFELLRFMMRNSKRVL  192

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  193  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  246


>gi|183985285|ref|YP_001853576.1| two-component transcriptional regulatory protein TcrX [Mycobacterium 
marinum M]
 gi|183178611|gb|ACC43721.1| two-component transcriptional regulatory protein TcrX [Mycobacterium 
marinum M]
Length=235

 Score =  422 bits (1086),  Expect = 2e-116, Method: Compositional matrix adjust.
 Identities = 219/234 (94%), Positives = 226/234 (97%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADGQPV+VLVVDDEPVLAEMVSMALRYEGWNI TA DG+SAIA+AR +RPDVVVLDV
Sbjct  2    MCRADGQPVSVLVVDDEPVLAEMVSMALRYEGWNIATASDGASAIASARAERPDVVVLDV  61

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGL+VLH+LR ENP LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  62   MLPDMSGLEVLHRLRKENPALPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  121

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  122  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVTRAGEPISLTSTEFELLRFMMRNSKRVL  181

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  182  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  235


>gi|254773313|ref|ZP_05214829.1| DNA-binding response regulator [Mycobacterium avium subsp. avium 
ATCC 25291]
Length=234

 Score =  422 bits (1084),  Expect = 2e-116, Method: Compositional matrix adjust.
 Identities = 220/234 (95%), Positives = 223/234 (96%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADG P+ VLVVDDE VLAEMVSMALRYEGWNI TA DG+SAIAAAR QRPDVVVLDV
Sbjct  1    MCRADGNPINVLVVDDEAVLAEMVSMALRYEGWNIATASDGASAIAAARNQRPDVVVLDV  60

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLR ENP LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  61   MLPDMSGLDVLHKLREENPQLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVTRAGEPISLTSTEFELLRFMMRNSKRVL  180

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234


>gi|254822466|ref|ZP_05227467.1| DNA-binding response regulator [Mycobacterium intracellulare 
ATCC 13950]
Length=234

 Score =  421 bits (1082),  Expect = 5e-116, Method: Compositional matrix adjust.
 Identities = 220/234 (95%), Positives = 224/234 (96%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADG P+ VLVVDDEPVLAEMVSMALRYEGWNI+TAGDG SAIAAAR QRPDVVVLDV
Sbjct  1    MCRADGNPINVLVVDDEPVLAEMVSMALRYEGWNISTAGDGESAIAAARNQRPDVVVLDV  60

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLR E P LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  61   MLPDMSGLDVLHKLRGEIPQLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVTRAGEPISLTSTEFELLRFMMRNSKRVL  180

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGR+PMIHTLRGAGYVLKPAR
Sbjct  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGRDPMIHTLRGAGYVLKPAR  234


>gi|342860017|ref|ZP_08716669.1| DNA-binding response regulator [Mycobacterium colombiense CECT 
3035]
 gi|342132395|gb|EGT85624.1| DNA-binding response regulator [Mycobacterium colombiense CECT 
3035]
Length=234

 Score =  421 bits (1081),  Expect = 5e-116, Method: Compositional matrix adjust.
 Identities = 219/234 (94%), Positives = 224/234 (96%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADG P+ VLVVDDE VLA+MVSMALRYEGWNI+TAGDG+SAIA AR QRPDVVVLDV
Sbjct  1    MCRADGNPINVLVVDDESVLADMVSMALRYEGWNISTAGDGASAIATARTQRPDVVVLDV  60

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLR ENP LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  61   MLPDMSGLDVLHKLREENPQLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVTRAGEPISLTSTEFELLRFMMRNSKRVL  180

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234


>gi|296166889|ref|ZP_06849306.1| DNA-binding response regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295897766|gb|EFG77355.1| DNA-binding response regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=236

 Score =  419 bits (1076),  Expect = 2e-115, Method: Compositional matrix adjust.
 Identities = 218/234 (94%), Positives = 224/234 (96%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADG P+ VLVVDDE VLAEMVSMALRYEGWNI TAGDG+SA+AAAR QRPDVVVLDV
Sbjct  3    MCRADGNPINVLVVDDESVLAEMVSMALRYEGWNIATAGDGASALAAARGQRPDVVVLDV  62

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLR ENP LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  63   MLPDMSGLDVLHKLREENPQLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  122

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTT+DSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  123  RALLRRTGVTTLDSGAQLVVGDLVLDEDSHEVTRAGEPISLTSTEFELLRFMMRNSKRVL  182

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGR+PMIHTLRGAGYVLKPAR
Sbjct  183  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGRDPMIHTLRGAGYVLKPAR  236


>gi|336460748|gb|EGO39636.1| response regulator with CheY-like receiver domain-containing 
protein [Mycobacterium avium subsp. paratuberculosis S397]
Length=234

 Score =  417 bits (1071),  Expect = 9e-115, Method: Compositional matrix adjust.
 Identities = 218/234 (94%), Positives = 221/234 (95%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADG P+ VLVVDDE VLAEMVSMALRYEGWNI TA DG+SAIAAAR QRPDVVVLDV
Sbjct  1    MCRADGNPINVLVVDDEAVLAEMVSMALRYEGWNIATASDGASAIAAARNQRPDVVVLDV  60

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVLHKLR  NP LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  61   MLPDMSGLDVLHKLREANPQLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVTRAGEPISLTSTEFELLRFMMRNSKRVL  180

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQIL RVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  181  SKAQILGRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234


>gi|118619527|ref|YP_907859.1| two component transcriptional regulatory protein TcrX [Mycobacterium 
ulcerans Agy99]
 gi|118571637|gb|ABL06388.1| two component transcriptional regulatory protein TcrX [Mycobacterium 
ulcerans Agy99]
Length=234

 Score =  417 bits (1071),  Expect = 9e-115, Method: Compositional matrix adjust.
 Identities = 216/234 (93%), Positives = 225/234 (97%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADGQPV+VLVVDDEPVLA+MVSMALRYEGWNI TA DG+SAIA+AR +RPDVVVLDV
Sbjct  1    MCRADGQPVSVLVVDDEPVLADMVSMALRYEGWNIATASDGASAIASARAERPDVVVLDV  60

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGL+VLH+LR ENP LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEE+VLRL
Sbjct  61   MLPDMSGLEVLHRLRKENPRLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEIVLRL  120

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVTRAGEPISLTSTEFELLRFMMRNSKRVL  180

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            S AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR
Sbjct  181  SNAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234


>gi|240168529|ref|ZP_04747188.1| two-component transcriptional regulatory protein TcrX [Mycobacterium 
kansasii ATCC 12478]
Length=234

 Score =  403 bits (1035),  Expect = 1e-110, Method: Compositional matrix adjust.
 Identities = 220/234 (95%), Positives = 225/234 (97%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADGQP++VLVVDDEPVLAEMVSMALRYEGWNITTA DG+SAIAAAR  RPDVVVLDV
Sbjct  1    MSRADGQPISVLVVDDEPVLAEMVSMALRYEGWNITTAQDGASAIAAARAARPDVVVLDV  60

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGL+VLHKLR ENP LPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  61   MLPDMSGLEVLHKLRRENPRLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEV RAGEP+SLTSTEFELLRFMM NSKRVL
Sbjct  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVARAGEPISLTSTEFELLRFMMRNSKRVL  180

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGR PMIHTLRGAGYVLKPAR
Sbjct  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGRAPMIHTLRGAGYVLKPAR  234


>gi|118470471|ref|YP_889241.1| DNA-binding response regulator [Mycobacterium smegmatis str. 
MC2 155]
 gi|118171758|gb|ABK72654.1| DNA-binding response regulator [Mycobacterium smegmatis str. 
MC2 155]
Length=249

 Score =  390 bits (1002),  Expect = 8e-107, Method: Compositional matrix adjust.
 Identities = 201/234 (86%), Positives = 220/234 (95%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADG P+ VLVVDDEPVLAE+VSMALRYEGW+ITTAGDG+SAIAAAR   PDVVVLDV
Sbjct  16   MRRADGNPIRVLVVDDEPVLAELVSMALRYEGWDITTAGDGASAIAAARETPPDVVVLDV  75

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVL KLR + PGLP+LLLTAKD+VEDRIAGLTAGGDDYVTKPFS+EEVVLRL
Sbjct  76   MLPDMSGLDVLRKLREQIPGLPLLLLTAKDSVEDRIAGLTAGGDDYVTKPFSLEEVVLRL  135

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGVT+ D GA++VVGDLVLDEDSHEV R G+P++LT+TEFELLRFMM N+KRVL
Sbjct  136  RALLRRTGVTSEDGGAKIVVGDLVLDEDSHEVTRGGDPIALTATEFELLRFMMRNAKRVL  195

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELY+SYLRKKID+GREPMIHTLRGAGYVL+P R
Sbjct  196  SKAQILDRVWSYDFGGRSNIVELYVSYLRKKIDSGREPMIHTLRGAGYVLRPPR  249


>gi|120405382|ref|YP_955211.1| two component transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119958200|gb|ABM15205.1| two component transcriptional regulator, winged helix family 
[Mycobacterium vanbaalenii PYR-1]
Length=250

 Score =  385 bits (989),  Expect = 3e-105, Method: Compositional matrix adjust.
 Identities = 199/234 (86%), Positives = 218/234 (94%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADG P+ VLVVDDEPVLAE+VSMALRYEGW I+TAGDG++AIA AR   PDVVVLDV
Sbjct  17   MRRADGSPIHVLVVDDEPVLAELVSMALRYEGWEISTAGDGATAIAIARDNPPDVVVLDV  76

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGL+VL KLR + PGLP+LLLTAKD+VEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  77   MLPDMSGLEVLRKLREQIPGLPLLLLTAKDSVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  136

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGV+T  SGA++VVGDLVLDEDSHEV R G+P++LT+TEFELLRFMM N+KRVL
Sbjct  137  RALLRRTGVSTDTSGAKIVVGDLVLDEDSHEVTRGGDPITLTATEFELLRFMMRNAKRVL  196

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SK QILDRVWSYDFGGRSNIVELY+SYLRKKID+GREPMIHTLRGAGYVLKPAR
Sbjct  197  SKTQILDRVWSYDFGGRSNIVELYVSYLRKKIDSGREPMIHTLRGAGYVLKPAR  250


>gi|108800890|ref|YP_641087.1| two component transcriptional regulator [Mycobacterium sp. MCS]
 gi|119870030|ref|YP_939982.1| two component transcriptional regulator [Mycobacterium sp. KMS]
 gi|126436516|ref|YP_001072207.1| two component transcriptional regulator [Mycobacterium sp. JLS]
 gi|108771309|gb|ABG10031.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. MCS]
 gi|119696119|gb|ABL93192.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. KMS]
 gi|126236316|gb|ABN99716.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. JLS]
Length=254

 Score =  380 bits (977),  Expect = 6e-104, Method: Compositional matrix adjust.
 Identities = 199/233 (86%), Positives = 216/233 (93%), Gaps = 1/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADG PV VLVVDDEPVLAE+VSMALRYEGW+I TAGDG++AIA AR   PDVVVLDV
Sbjct  21   MRRADGNPVRVLVVDDEPVLAELVSMALRYEGWDIATAGDGATAIALARENPPDVVVLDV  80

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVL KLR + PGLP+LLLTAKD+VEDRIAGLTAGGDDYVTKPFS+EEVVLRL
Sbjct  81   MLPDMSGLDVLAKLREQIPGLPLLLLTAKDSVEDRIAGLTAGGDDYVTKPFSLEEVVLRL  140

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGV+    GA++VVGDLVLDEDSHEV R G+P++LT+TEFELLRFMM NSKRVL
Sbjct  141  RALLRRTGVSE-SGGAKIVVGDLVLDEDSHEVTRGGDPITLTATEFELLRFMMRNSKRVL  199

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVWSYDFGGRSNIVELY+SYLRKKID+GREPMIHTLRGAGYVLKPA
Sbjct  200  SKAQILDRVWSYDFGGRSNIVELYVSYLRKKIDSGREPMIHTLRGAGYVLKPA  252


>gi|333992682|ref|YP_004525296.1| two-component transcriptional regulatory protein TcrX [Mycobacterium 
sp. JDM601]
 gi|333488650|gb|AEF38042.1| two-component transcriptional regulatory protein TcrX [Mycobacterium 
sp. JDM601]
Length=235

 Score =  377 bits (967),  Expect = 1e-102, Method: Compositional matrix adjust.
 Identities = 200/233 (86%), Positives = 218/233 (94%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADG+P+TVLVVDDE VLAEMVSMALRYEGW   TAGDG+SAIAAA+ +RPDVVVLDV
Sbjct  2    MARADGKPITVLVVDDETVLAEMVSMALRYEGWTTATAGDGASAIAAAKAERPDVVVLDV  61

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGLDVL KLR  NP LPVL LTAKDA+EDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  62   MLPDMSGLDVLRKLREINPRLPVLFLTAKDALEDRIAGLTAGGDDYVTKPFSIEEVVLRL  121

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGV+T ++GAQ+VVGDLVLDEDSHEV R G+P++LTSTEFELLR++MHN++RVL
Sbjct  122  RALLRRTGVSTAEAGAQIVVGDLVLDEDSHEVTRGGDPITLTSTEFELLRYLMHNARRVL  181

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVW YDFGGR+NIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA
Sbjct  182  SKAQILDRVWDYDFGGRANIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  234


>gi|145222854|ref|YP_001133532.1| two component transcriptional regulator [Mycobacterium gilvum 
PYR-GCK]
 gi|315443319|ref|YP_004076198.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
 gi|145215340|gb|ABP44744.1| two component transcriptional regulator, winged helix family 
[Mycobacterium gilvum PYR-GCK]
 gi|315261622|gb|ADT98363.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
Length=249

 Score =  373 bits (958),  Expect = 1e-101, Method: Compositional matrix adjust.
 Identities = 194/234 (83%), Positives = 215/234 (92%), Gaps = 0/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            MRRADG P+ VLVVDDE VLAE++SMALRYEGW+I+TAGDG++AIA AR+  PDVVVLDV
Sbjct  16   MRRADGSPIRVLVVDDEAVLAELMSMALRYEGWDISTAGDGATAIALARQNPPDVVVLDV  75

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDMSGL+VL  LR + PGLP+LLLTAKD+VEDRIAGLTAGGDDYVTKPFSIEEVVLRL
Sbjct  76   MLPDMSGLEVLRTLREQIPGLPLLLLTAKDSVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  135

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRRTGV T   GA+LVVGDLVLDEDSHEV R G+ ++LT+TEFELLRFMM N++ VL
Sbjct  136  RALLRRTGVATATGGAKLVVGDLVLDEDSHEVTRGGDLITLTATEFELLRFMMRNARCVL  195

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            SKAQILDRVWSYDFGGRSNIVELY+SYLRKKID+GREPMIHTLRGAGYVLKPAR
Sbjct  196  SKAQILDRVWSYDFGGRSNIVELYVSYLRKKIDSGREPMIHTLRGAGYVLKPAR  249


>gi|331698780|ref|YP_004335019.1| winged helix family two component transcriptional regulator [Pseudonocardia 
dioxanivorans CB1190]
 gi|326953469|gb|AEA27166.1| two component transcriptional regulator, winged helix family 
[Pseudonocardia dioxanivorans CB1190]
Length=247

 Score =  348 bits (893),  Expect = 4e-94, Method: Compositional matrix adjust.
 Identities = 167/233 (72%), Positives = 197/233 (85%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            ++RADG  V VLVVDDE  L++++ MALRYEGW++ T  DG+SA+ AAR  RPD VVLDV
Sbjct  12   LQRADGSAVRVLVVDDEATLSDLLGMALRYEGWDVRTEADGASAVRAAREFRPDAVVLDV  71

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD+ GL+VL ++R++ P +PVL LTAKDAVEDR+AGLTAGGDDYVTKPFS+EE+V RL
Sbjct  72   MLPDLDGLEVLRRMRADTPDVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEELVARL  131

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            R LLRR+G+T    G++L VGDL LDEDSHEV R    V LT+TEFELLRF+M N +RVL
Sbjct  132  RGLLRRSGMTAAQQGSELAVGDLTLDEDSHEVRRGDVEVDLTATEFELLRFLMRNPRRVL  191

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVW YDFGG+SN+VELYISYLRKKIDNGR PMIHT+RGAGYVLKPA
Sbjct  192  SKAQILDRVWHYDFGGQSNVVELYISYLRKKIDNGRAPMIHTVRGAGYVLKPA  244


>gi|297200795|ref|ZP_06918192.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sviceus ATCC 29083]
 gi|197712366|gb|EDY56400.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sviceus ATCC 29083]
Length=269

 Score =  344 bits (883),  Expect = 5e-93, Method: Compositional matrix adjust.
 Identities = 170/231 (74%), Positives = 193/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG+ A+  AR  RPD VVLD+ML
Sbjct  37   RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGTGAVQTAREFRPDAVVLDMML  96

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  97   PDMDGLAVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  156

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S + LVVGDL LDEDSHEV RAGE + LT+TEFELLRF+M N +RVLSK
Sbjct  157  LIRRSGAADRRSDSVLVVGDLTLDEDSHEVSRAGENIHLTATEFELLRFLMRNPRRVLSK  216

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  217  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  267


>gi|302552564|ref|ZP_07304906.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
viridochromogenes DSM 40736]
 gi|302470182|gb|EFL33275.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
viridochromogenes DSM 40736]
Length=268

 Score =  343 bits (880),  Expect = 1e-92, Method: Compositional matrix adjust.
 Identities = 170/231 (74%), Positives = 193/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG  AI +AR  RPD VVLD+ML
Sbjct  36   RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGQGAIQSARDFRPDAVVLDMML  95

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  96   PDMDGLAVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  155

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S + LVVGDL LDEDSHEV RAG+ + LT+TEFELLRF+M N +RVLSK
Sbjct  156  LIRRSGAADRRSESMLVVGDLTLDEDSHEVTRAGDNIHLTATEFELLRFLMRNPRRVLSK  215

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  216  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  266


>gi|29830741|ref|NP_825375.1| two-component system response regulator [Streptomyces avermitilis 
MA-4680]
 gi|29607854|dbj|BAC71910.1| putative two-component system response regulator [Streptomyces 
avermitilis MA-4680]
Length=269

 Score =  343 bits (879),  Expect = 1e-92, Method: Compositional matrix adjust.
 Identities = 169/231 (74%), Positives = 192/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG  A+  AR  RPD VVLD+ML
Sbjct  37   RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGQGAVQTAREFRPDAVVLDMML  96

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  97   PDMDGLTVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  156

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S + LVVGDL LDEDSHEV R+GE + LT+TEFELLRF+M N +RVLSK
Sbjct  157  LIRRSGAADRRSDSMLVVGDLTLDEDSHEVSRSGENIHLTATEFELLRFLMRNPRRVLSK  216

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  217  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  267


>gi|324999382|ref|ZP_08120494.1| two component transcriptional regulator, winged helix family 
protein [Pseudonocardia sp. P1]
Length=246

 Score =  343 bits (879),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 161/233 (70%), Positives = 197/233 (85%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            +RRADG P+ VLVVDDE  L++++SMALRYEGW + TAGDG++A+  AR  RPD +VLDV
Sbjct  12   LRRADGSPIRVLVVDDESTLSDLLSMALRYEGWEVRTAGDGATAVRHAREFRPDAIVLDV  71

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD+ G +VL ++R+  P +PVL LTA+DAVEDR+AGLTAGGDDYVTKPFS+EE+V RL
Sbjct  72   MLPDVDGFEVLRRVRAGTPEVPVLFLTARDAVEDRVAGLTAGGDDYVTKPFSLEELVARL  131

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            R LLRR G+      ++LVVGDLVLDED+HEV RA  P+ LT+TEFELLR++M N +RVL
Sbjct  132  RGLLRRAGMAAAQRSSELVVGDLVLDEDAHEVRRADRPIELTATEFELLRYLMRNPRRVL  191

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVW+YDFGG+SN+VELY+SYLRKKID G  PMIHT+RGAGYVL+PA
Sbjct  192  SKAQILDRVWNYDFGGQSNVVELYVSYLRKKIDAGYAPMIHTVRGAGYVLRPA  244


>gi|296394075|ref|YP_003658959.1| transcriptional regulator [Segniliparus rotundus DSM 44985]
 gi|296181222|gb|ADG98128.1| two component transcriptional regulator, winged helix family 
[Segniliparus rotundus DSM 44985]
Length=241

 Score =  343 bits (879),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 180/233 (78%), Positives = 197/233 (85%), Gaps = 0/233 (0%)

Query  2    RRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVM  61
            RRA G P  VLVVDDE  LAE+VSMALR EGW    A DG+ AI  AR   PDVVVLDVM
Sbjct  9    RRAGGGPARVLVVDDEQALAELVSMALRREGWEPAVAFDGAGAIKLARDAAPDVVVLDVM  68

Query  62   LPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLR  121
            LPDMSGL+VL +LR   P LP+LLLTAKDAVEDRIAGLTAGGDDYVTKPFS+EE++LR+R
Sbjct  69   LPDMSGLEVLLRLREMYPALPLLLLTAKDAVEDRIAGLTAGGDDYVTKPFSLEELMLRVR  128

Query  122  ALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLS  181
            ALLRR G+   DS A++VVGDLVLDEDSHEV R G+P+ LT+TEFELLRFMM N+KRVLS
Sbjct  129  ALLRRAGMAGEDSDARIVVGDLVLDEDSHEVSRGGDPIVLTATEFELLRFMMRNAKRVLS  188

Query  182  KAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPAR  234
            K QILDRVWSYDFGGRSNIVELY+SYLRKKID  REPMIHTLRG GYVLKPAR
Sbjct  189  KNQILDRVWSYDFGGRSNIVELYVSYLRKKIDTEREPMIHTLRGVGYVLKPAR  241


>gi|302544103|ref|ZP_07296445.1| DNA-binding response regulator TrcR [Streptomyces hygroscopicus 
ATCC 53653]
 gi|302461721|gb|EFL24814.1| DNA-binding response regulator TrcR [Streptomyces himastatinicus 
ATCC 53653]
Length=290

 Score =  342 bits (877),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 168/231 (73%), Positives = 191/231 (83%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  LA+++SMALRYEGW + TAGDG+ AI   R  RPD VVLDVML
Sbjct  59   RPDGSPVRVLVVDDESALADLLSMALRYEGWEVRTAGDGAEAIRTTRELRPDAVVLDVML  118

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTA+DAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  119  PDMDGLTVLGRLRRELPEVPVLFLTARDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  178

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            LLRR+G     S + L VGDLVLDEDSHEV RAG+ + LT+TEFELLR++M N +RVLSK
Sbjct  179  LLRRSGAAAARSESVLAVGDLVLDEDSHEVSRAGQEIHLTATEFELLRYLMRNPRRVLSK  238

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GR PMIHT RGAGY++KP 
Sbjct  239  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGRSPMIHTRRGAGYLIKPG  289


>gi|294630229|ref|ZP_06708789.1| DNA-binding response regulator TrcR [Streptomyces sp. e14]
 gi|292833562|gb|EFF91911.1| DNA-binding response regulator TrcR [Streptomyces sp. e14]
Length=269

 Score =  341 bits (875),  Expect = 5e-92, Method: Compositional matrix adjust.
 Identities = 168/231 (73%), Positives = 190/231 (83%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG  A+  AR  RPD VVLD+ML
Sbjct  37   RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGQGAVQTAREFRPDAVVLDMML  96

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  97   PDMDGLTVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  156

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR G     S + LVVGDL LDEDSHEV R G+ + LT+TEFELLRF+M N +RVLSK
Sbjct  157  LIRRAGAADRRSESVLVVGDLTLDEDSHEVSRGGQDIHLTATEFELLRFLMRNPRRVLSK  216

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  217  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  267


>gi|290959131|ref|YP_003490313.1| two component system response regulator [Streptomyces scabiei 
87.22]
 gi|260648657|emb|CBG71770.1| putative two component system response regulator [Streptomyces 
scabiei 87.22]
Length=249

 Score =  341 bits (874),  Expect = 5e-92, Method: Compositional matrix adjust.
 Identities = 169/231 (74%), Positives = 193/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG+ A+  AR  RPD VVLD+ML
Sbjct  17   RPDGSPVRVLVVDDELSITELLSMALRYEGWQIRSAGDGTGALQTARDFRPDAVVLDMML  76

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  77   PDMDGLTVLGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  136

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S + LVVGDL+LDEDSHEV RAG  + LT+TEFELLRF+M N +RVLSK
Sbjct  137  LIRRSGAADRRSDSVLVVGDLMLDEDSHEVSRAGANIHLTATEFELLRFLMRNPRRVLSK  196

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  197  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  247


>gi|145594662|ref|YP_001158959.1| response regulator receiver [Salinispora tropica CNB-440]
 gi|145303999|gb|ABP54581.1| response regulator receiver [Salinispora tropica CNB-440]
Length=252

 Score =  341 bits (874),  Expect = 6e-92, Method: Compositional matrix adjust.
 Identities = 167/234 (72%), Positives = 197/234 (85%), Gaps = 1/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            +RR DGQPV VLVVDDE  LA+++SMALRYEGW + TAG+G +A++AAR+ +PD VVLDV
Sbjct  18   LRRPDGQPVRVLVVDDESTLADLLSMALRYEGWQVRTAGNGMAALSAARQFQPDAVVLDV  77

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD+ G  VL +LR   P +PVL LTA+DAVEDR+AGLT GGDDYVTKPFS+EEV+ RL
Sbjct  78   MLPDLDGFAVLRRLREVAPTVPVLFLTARDAVEDRVAGLTVGGDDYVTKPFSLEEVIARL  137

Query  121  RALLRRTGVT-TVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRV  179
            RALLRR+G   T    A L VGDL LDEDSHEV R G+ ++LT+TEFELLR++M N +RV
Sbjct  138  RALLRRSGFAVTARQEAVLTVGDLSLDEDSHEVSRDGQLINLTATEFELLRYLMRNPRRV  197

Query  180  LSKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            LSKAQILDRVW+YDFGG++N+VELYISYLRKKID GR PMIHTLRGAGYVLKPA
Sbjct  198  LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDVGRAPMIHTLRGAGYVLKPA  251


>gi|297625540|ref|YP_003687303.1| two component system response regulator [Propionibacterium freudenreichii 
subsp. shermanii CIRM-BIA1]
 gi|32452353|emb|CAD59399.1| putative two-component system regulatory protein [Propionibacterium 
freudenreichii subsp. shermanii]
 gi|296921305|emb|CBL55858.1| two component system response regulator [Propionibacterium freudenreichii 
subsp. shermanii CIRM-BIA1]
Length=242

 Score =  340 bits (873),  Expect = 8e-92, Method: Compositional matrix adjust.
 Identities = 161/233 (70%), Positives = 195/233 (84%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            + R DG P+ VL VDDE  L E++SMA+RYEGW  TTA  GS A+ AAR   PD +VLD+
Sbjct  10   LTRPDGTPIRVLAVDDENSLTELLSMAMRYEGWEPTTAATGSDAVRAARDTNPDAIVLDM  69

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD  GL+V+ ++R+E P +PV+ LTAKDAV DRI GLTAGGDDYVTKPFS+EE++ RL
Sbjct  70   MLPDFDGLEVMRRVRAEQPDVPVIFLTAKDAVNDRIVGLTAGGDDYVTKPFSVEELMARL  129

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            R+LLRR+G T+  S ++L+VGDLVLDEDSHEV R G+ + LT+TEFELLR++M N KRVL
Sbjct  130  RSLLRRSGATSKRSESELIVGDLVLDEDSHEVTRGGDEIHLTATEFELLRYLMRNPKRVL  189

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVW+YDFGG++N+VELYISYLRKKID GREPMIHT+RGAGYVLKPA
Sbjct  190  SKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGREPMIHTMRGAGYVLKPA  242


>gi|302559780|ref|ZP_07312122.1| DNA-binding response regulator TrcR [Streptomyces griseoflavus 
Tu4000]
 gi|302477398|gb|EFL40491.1| DNA-binding response regulator TrcR [Streptomyces griseoflavus 
Tu4000]
Length=249

 Score =  340 bits (873),  Expect = 9e-92, Method: Compositional matrix adjust.
 Identities = 167/231 (73%), Positives = 191/231 (83%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG  A+  AR  RPD VVLD+ML
Sbjct  17   RPDGSPVRVLVVDDEQSITELLSMALRYEGWQIRSAGDGQGALRTAREFRPDAVVLDMML  76

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL +L +LR E P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  77   PDMDGLAILGRLRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  136

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S + LVVGDL LDEDSHEV R G+ + LT+TEFELLRF+M N +RVLSK
Sbjct  137  LIRRSGAADRRSESMLVVGDLTLDEDSHEVTRGGDGIHLTATEFELLRFLMRNPRRVLSK  196

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  197  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  247


>gi|21222423|ref|NP_628202.1| two component system response regulator [Streptomyces coelicolor 
A3(2)]
 gi|13122184|emb|CAC32360.1| putative two component system response regulator [Streptomyces 
coelicolor A3(2)]
Length=271

 Score =  340 bits (872),  Expect = 1e-91, Method: Compositional matrix adjust.
 Identities = 167/231 (73%), Positives = 192/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG  A+  AR  RPD VVLD+ML
Sbjct  39   RPDGSPVRVLVVDDEQSITELLSMALRYEGWQIRSAGDGHGAVQTARDFRPDAVVLDMML  98

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR + P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  99   PDMDGLSVLGRLRRDLPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  158

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S + LVVGDL LDEDSHEV R+G+ + LT+TEFELLRF+M N +RVLSK
Sbjct  159  LIRRSGAADRRSDSVLVVGDLTLDEDSHEVTRSGDGIHLTATEFELLRFLMRNPRRVLSK  218

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  219  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  269


>gi|289770395|ref|ZP_06529773.1| two component system response regulator [Streptomyces lividans 
TK24]
 gi|289700594|gb|EFD68023.1| two component system response regulator [Streptomyces lividans 
TK24]
Length=285

 Score =  340 bits (871),  Expect = 1e-91, Method: Compositional matrix adjust.
 Identities = 167/231 (73%), Positives = 192/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG  A+  AR  RPD VVLD+ML
Sbjct  53   RPDGSPVRVLVVDDEQSITELLSMALRYEGWQIRSAGDGHGAVQTARDFRPDAVVLDMML  112

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR + P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  113  PDMDGLSVLGRLRRDLPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  172

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S + LVVGDL LDEDSHEV R+G+ + LT+TEFELLRF+M N +RVLSK
Sbjct  173  LIRRSGAADRRSDSVLVVGDLTLDEDSHEVTRSGDGIHLTATEFELLRFLMRNPRRVLSK  232

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  233  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  283


>gi|119717917|ref|YP_924882.1| response regulator receiver [Nocardioides sp. JS614]
 gi|119538578|gb|ABL83195.1| response regulator receiver [Nocardioides sp. JS614]
Length=236

 Score =  340 bits (871),  Expect = 1e-91, Method: Compositional matrix adjust.
 Identities = 162/231 (71%), Positives = 192/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG P+ VLVVDDE  +AE++SMALRYEGW +  A  GS A+AAA+  RPD VVLD+ML
Sbjct  5    RPDGTPLRVLVVDDEANIAELISMALRYEGWQVRAAHTGSKAVAAAKEFRPDAVVLDIML  64

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PD  GL+VL ++RS +P +PV+ LTA+DAVEDR+AGLTAGGDDYVTKPFS+EE+V RLR 
Sbjct  65   PDFDGLEVLRRIRSTDPSVPVVFLTARDAVEDRVAGLTAGGDDYVTKPFSLEELVARLRG  124

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR G     + + LVVGDL LDEDS EV RAG  V+LT+TEFELLRF+M N +RVLSK
Sbjct  125  LMRRAGAQQATASSTLVVGDLELDEDSREVFRAGREVTLTATEFELLRFLMRNPRRVLSK  184

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVW+YDFGG++N+VELYISYLRKKID G EPMIHT+RGAGYVLKPA
Sbjct  185  AQILDRVWNYDFGGQANVVELYISYLRKKIDAGHEPMIHTMRGAGYVLKPA  235


>gi|269796544|ref|YP_003315999.1| CheY-like receiver domain/winged-helix DNA-binding domain-containing 
response regulator [Sanguibacter keddieii DSM 10542]
 gi|269098729|gb|ACZ23165.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Sanguibacter keddieii DSM 10542]
Length=271

 Score =  339 bits (870),  Expect = 2e-91, Method: Compositional matrix adjust.
 Identities = 161/233 (70%), Positives = 197/233 (85%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            + RADG P+ VLVVDDEP LAE+++ ALRYEGW+++TA DG +A+  AR   PDV+VLD+
Sbjct  15   LTRADGSPLRVLVVDDEPNLAELLTSALRYEGWDVSTALDGQTAVRLARETVPDVIVLDI  74

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            ML D+ GL+VL ++R +  G+PVL LTA+D+VEDR+AGLTAGGDDYVTKPFS+EEVV RL
Sbjct  75   MLGDIDGLEVLRRIRQQQEGVPVLFLTARDSVEDRVAGLTAGGDDYVTKPFSLEEVVARL  134

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            R LLRR G +     A+LVVGDL LDEDSHEV RAG+ + LT+TEFELLR++M N++RV+
Sbjct  135  RGLLRRAGASAARDEARLVVGDLTLDEDSHEVDRAGQEIHLTATEFELLRYLMRNARRVM  194

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SK+QILDRVW YDFGG++NIVELYISYLR+KID GREPMIHTLRG GYVLKPA
Sbjct  195  SKSQILDRVWQYDFGGQANIVELYISYLRRKIDAGREPMIHTLRGVGYVLKPA  247


>gi|302867311|ref|YP_003835948.1| response regulator receiver [Micromonospora aurantiaca ATCC 27029]
 gi|315506283|ref|YP_004085170.1| winged helix family two component transcriptional regulator [Micromonospora 
sp. L5]
 gi|302570170|gb|ADL46372.1| response regulator receiver [Micromonospora aurantiaca ATCC 27029]
 gi|315412902|gb|ADU11019.1| two component transcriptional regulator, winged helix family 
[Micromonospora sp. L5]
Length=246

 Score =  338 bits (868),  Expect = 3e-91, Method: Compositional matrix adjust.
 Identities = 163/234 (70%), Positives = 193/234 (83%), Gaps = 1/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            +RR DG+PV VLVVDDEP L +++SMALRYEGW + TAG G +A+  AR+ RPD VVLDV
Sbjct  12   LRRPDGEPVRVLVVDDEPTLTDLLSMALRYEGWQVATAGSGMAAVTTARQFRPDAVVLDV  71

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD+ G  VL +LR + P +PVL LTA+DAVE+R+AGLT GGDDYVTKPFS+EEV+ RL
Sbjct  72   MLPDLDGFQVLRRLREQFPSVPVLFLTARDAVEERVAGLTVGGDDYVTKPFSLEEVIARL  131

Query  121  RALLRRTGVT-TVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRV  179
            RALLRR+G        A L VGDL LDEDSHEV R  + ++LT+TEFELLR++M N +RV
Sbjct  132  RALLRRSGFAVAARQEAVLTVGDLTLDEDSHEVRRGDDLITLTATEFELLRYLMRNPRRV  191

Query  180  LSKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            LSKAQILDRVW+YDFGG++N+VELYISYLRKKID GR PMIHTLRGAGYVLKPA
Sbjct  192  LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGRAPMIHTLRGAGYVLKPA  245


>gi|300790732|ref|YP_003771023.1| two-component system response regulator [Amycolatopsis mediterranei 
U32]
 gi|299800246|gb|ADJ50621.1| two-component system response regulator [Amycolatopsis mediterranei 
U32]
Length=249

 Score =  338 bits (867),  Expect = 3e-91, Method: Compositional matrix adjust.
 Identities = 180/233 (78%), Positives = 198/233 (85%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            +RRADG PV VLVVDDE  LAE+VSMALR EGW + +AGDG+ A+  AR  RPD VVLDV
Sbjct  16   LRRADGSPVRVLVVDDEATLAELVSMALRMEGWEVRSAGDGTEAVRIAREFRPDAVVLDV  75

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD SGL+VL ++RSE P LPVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEV LRL
Sbjct  76   MLPDFSGLEVLRRMRSEAPQLPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVALRL  135

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRR G  T  SG+ LVVGDL LDEDS EV R G+ V LT+TEFELLR++M N KRVL
Sbjct  136  RALLRRAGGVTGASGSTLVVGDLTLDEDSREVHRGGDLVPLTATEFELLRYLMRNPKRVL  195

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVWSYDFGG++NIVELYISYLRKKID  REPMIHT+RGAGYVLKPA
Sbjct  196  SKAQILDRVWSYDFGGQANIVELYISYLRKKIDADREPMIHTMRGAGYVLKPA  248


>gi|291438629|ref|ZP_06578019.1| two-component system response regulator [Streptomyces ghanaensis 
ATCC 14672]
 gi|291341524|gb|EFE68480.1| two-component system response regulator [Streptomyces ghanaensis 
ATCC 14672]
Length=268

 Score =  338 bits (867),  Expect = 4e-91, Method: Compositional matrix adjust.
 Identities = 166/231 (72%), Positives = 190/231 (83%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I + GDG  A+ AAR  RPD VVLD+ML
Sbjct  37   RPDGGPVRVLVVDDEQSITELLSMALRYEGWQIHSEGDGQGALRAARELRPDAVVLDMML  96

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTAK +VE+R+AGLTAGGDDYVTKPF +EEVV RLR 
Sbjct  97   PDMDGLSVLGRLRRELPDVPVLFLTAKGSVEERVAGLTAGGDDYVTKPFGLEEVVARLRG  156

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     +G+ LVVGDL LDEDSHEV RAGE + LT+TEFELLRF+M N +RVLSK
Sbjct  157  LIRRSGAADRRAGSLLVVGDLTLDEDSHEVTRAGEGIHLTATEFELLRFLMRNPRRVLSK  216

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG +N+VELYISYLRKKID GREPMIHT RGAGY++KPA
Sbjct  217  AQILDRVWSYDFGGHANVVELYISYLRKKIDAGREPMIHTRRGAGYMIKPA  267


>gi|340532422|gb|AEK47627.1| two-component system response regulator [Amycolatopsis mediterranei 
S699]
Length=246

 Score =  338 bits (867),  Expect = 4e-91, Method: Compositional matrix adjust.
 Identities = 180/233 (78%), Positives = 198/233 (85%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            +RRADG PV VLVVDDE  LAE+VSMALR EGW + +AGDG+ A+  AR  RPD VVLDV
Sbjct  13   LRRADGSPVRVLVVDDEATLAELVSMALRMEGWEVRSAGDGTEAVRIAREFRPDAVVLDV  72

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD SGL+VL ++RSE P LPVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEV LRL
Sbjct  73   MLPDFSGLEVLRRMRSEAPQLPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVALRL  132

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RALLRR G  T  SG+ LVVGDL LDEDS EV R G+ V LT+TEFELLR++M N KRVL
Sbjct  133  RALLRRAGGVTGASGSTLVVGDLTLDEDSREVHRGGDLVPLTATEFELLRYLMRNPKRVL  192

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVWSYDFGG++NIVELYISYLRKKID  REPMIHT+RGAGYVLKPA
Sbjct  193  SKAQILDRVWSYDFGGQANIVELYISYLRKKIDADREPMIHTMRGAGYVLKPA  245


>gi|345016321|ref|YP_004818675.1| winged helix family two component transcriptional regulator [Streptomyces 
violaceusniger Tu 4113]
 gi|344042670|gb|AEM88395.1| two component transcriptional regulator, winged helix family 
[Streptomyces violaceusniger Tu 4113]
Length=245

 Score =  338 bits (866),  Expect = 5e-91, Method: Compositional matrix adjust.
 Identities = 166/231 (72%), Positives = 189/231 (82%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  LA+++SMALRYEGW + TAGDG+ AI   R  RPD VVLDVML
Sbjct  14   RPDGSPVRVLVVDDESALADLLSMALRYEGWEVRTAGDGAEAIRITRELRPDAVVLDVML  73

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTA+DAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  74   PDMDGLTVLGRLRRELPDIPVLFLTARDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  133

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            LLRR+G     S + L VGDL+LDEDSHEV R G  + LT+TEFELLR++M N +RVLSK
Sbjct  134  LLRRSGAAAARSESVLAVGDLILDEDSHEVSRGGREIHLTATEFELLRYLMRNPRRVLSK  193

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GR PMIHT RGAGY++KP 
Sbjct  194  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGRSPMIHTRRGAGYLIKPG  244


>gi|336116252|ref|YP_004571018.1| two-component system response regulator [Microlunatus phosphovorus 
NM-1]
 gi|334684030|dbj|BAK33615.1| two-component system response regulator [Microlunatus phosphovorus 
NM-1]
Length=248

 Score =  338 bits (866),  Expect = 5e-91, Method: Compositional matrix adjust.
 Identities = 158/231 (69%), Positives = 193/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG  + +L VDDE  L E++SMA+RYEGW ++TA  GS A+ AAR  RPD +VLD+ML
Sbjct  17   RPDGTAIRILAVDDESSLTELLSMAMRYEGWQVSTAASGSEAVKAAREVRPDAIVLDMML  76

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PD  GL+V+ ++R+E+P +PV+ LTAKDAV DRI+GLTAGGDDYVTKPFS+EEV+ RLRA
Sbjct  77   PDFDGLEVMRRVRAEDPDVPVIFLTAKDAVADRISGLTAGGDDYVTKPFSLEEVIARLRA  136

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            LLRR+G  T  S + LVVGDL LDEDSHEV RAG+ + LT+TEFELLR++M N +RVLSK
Sbjct  137  LLRRSGAATGRSESLLVVGDLTLDEDSHEVARAGDAIQLTATEFELLRYLMRNPRRVLSK  196

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVW+YDFGG++N+VELYISYLRKKID  R PMIHT+RGAGYVL+PA
Sbjct  197  AQILDRVWNYDFGGQANVVELYISYLRKKIDANRAPMIHTMRGAGYVLRPA  247


>gi|330468634|ref|YP_004406377.1| two component transcriptional regulator [Verrucosispora maris 
AB-18-032]
 gi|328811605|gb|AEB45777.1| two component transcriptional regulator [Verrucosispora maris 
AB-18-032]
Length=247

 Score =  338 bits (866),  Expect = 5e-91, Method: Compositional matrix adjust.
 Identities = 163/234 (70%), Positives = 198/234 (85%), Gaps = 1/234 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            +RR DG+ V VLVVDDEP L +++SMALRYEGW + TAGDG  AI AAR+ +PD VVLDV
Sbjct  13   LRRPDGEAVRVLVVDDEPTLTDLLSMALRYEGWQVRTAGDGMGAIRAARQFQPDAVVLDV  72

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD+ G +VL KLR ++  +PVL LTA+DAVE+R+AGLT GGDDYVTKPFS+EEV+ RL
Sbjct  73   MLPDLDGFEVLRKLREDDATVPVLFLTARDAVEERVAGLTVGGDDYVTKPFSLEEVIARL  132

Query  121  RALLRRTGVT-TVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRV  179
            RALLRR+G   T    A L VGDL L+E+SHEV R+G+ ++LT+TEFELLR++M N +RV
Sbjct  133  RALLRRSGFAVTARQDAVLTVGDLTLNEESHEVRRSGQLITLTATEFELLRYLMRNPRRV  192

Query  180  LSKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            LSKAQILDRVW+YDFGG++N+VELYISYLRKKID GR+PMIHTLRGAGY+LKPA
Sbjct  193  LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGRQPMIHTLRGAGYLLKPA  246


>gi|297193412|ref|ZP_06910810.1| two-component system response regulator [Streptomyces pristinaespiralis 
ATCC 25486]
 gi|297151766|gb|EFH31343.1| two-component system response regulator [Streptomyces pristinaespiralis 
ATCC 25486]
Length=247

 Score =  337 bits (865),  Expect = 6e-91, Method: Compositional matrix adjust.
 Identities = 164/233 (71%), Positives = 191/233 (82%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M R DG PV VLVVDDE  L+E++SMALRYEGW + +AGDG+ A+   R  RPD VVLD+
Sbjct  14   MLRPDGSPVRVLVVDDEAPLSELLSMALRYEGWEVRSAGDGAGAVRTVREFRPDAVVLDI  73

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPDM GL VL +LR E P +PVL LTA+DAVEDRIAGLTAGGDDYVTKPFS+EEVV RL
Sbjct  74   MLPDMDGLAVLGRLRREAPDVPVLFLTARDAVEDRIAGLTAGGDDYVTKPFSLEEVVARL  133

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            R L+RR+G   V S + L VGDL LDEDSHEV R G+ + LT+TEFELLR++M N +RVL
Sbjct  134  RGLIRRSGTAAVRSESLLAVGDLTLDEDSHEVTRGGQSIHLTATEFELLRYLMRNPRRVL  193

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVWSYDFGG++N+VELYISYLR+KID GR PMIHT RGAGY++KP 
Sbjct  194  SKAQILDRVWSYDFGGQANVVELYISYLRRKIDAGRPPMIHTRRGAGYLIKPG  246


>gi|111220170|ref|YP_710964.1| putative two-component system response regulator [Frankia alni 
ACN14a]
 gi|111147702|emb|CAJ59359.1| Putative two-component system response regulator (partial match) 
[Frankia alni ACN14a]
Length=358

 Score =  337 bits (865),  Expect = 6e-91, Method: Compositional matrix adjust.
 Identities = 164/228 (72%), Positives = 192/228 (85%), Gaps = 1/228 (0%)

Query  7    QPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVMLPDMS  66
            QPV VLVVDDE  LAE++SMALRYEGW + +AGDG  A+  AR  RPD VVLD+MLPDM 
Sbjct  17   QPVRVLVVDDETTLAELLSMALRYEGWEVRSAGDGRGALRLAREFRPDAVVLDIMLPDMD  76

Query  67   GLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRALLRR  126
            GL+VL +LR+E+P +PVL LTA+DAVEDR+AGLTAGGDDYVTKPFS+EE+V RLR L+RR
Sbjct  77   GLEVLRRLRAESPDVPVLFLTARDAVEDRVAGLTAGGDDYVTKPFSLEELVARLRGLMRR  136

Query  127  TGVTT-VDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSKAQI  185
               TT    GA+LVVGDL +DE+S EV R G PV LT+TEFELLRF M N +RVLSKAQI
Sbjct  137  AARTTEALQGARLVVGDLTMDEESREVARGGVPVHLTATEFELLRFFMRNPRRVLSKAQI  196

Query  186  LDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            LDRVW+YDFGG++N+VELY+SYLRKKID GR PMIHT+RGAGYVL+PA
Sbjct  197  LDRVWNYDFGGQANVVELYVSYLRKKIDAGRPPMIHTMRGAGYVLRPA  244


>gi|326333582|ref|ZP_08199821.1| DNA-binding response regulator TrcR [Nocardioidaceae bacterium 
Broad-1]
 gi|325948598|gb|EGD40699.1| DNA-binding response regulator TrcR [Nocardioidaceae bacterium 
Broad-1]
Length=244

 Score =  337 bits (865),  Expect = 7e-91, Method: Compositional matrix adjust.
 Identities = 162/233 (70%), Positives = 193/233 (83%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            + R DG P+ VLVVDDE  +AE++ MALRYEGW +  A  G+ A++AAR   PD +VLD 
Sbjct  11   LTRLDGSPLRVLVVDDEVNIAELIMMALRYEGWEVAAAHTGTKAVSAARDFTPDAIVLDW  70

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD  GL+VL ++RS NP +PVL LTAKDAVEDR+AGLTAGGDDYVTKPFS+EE+V RL
Sbjct  71   MLPDFDGLEVLRRVRSTNPAVPVLFLTAKDAVEDRVAGLTAGGDDYVTKPFSLEELVARL  130

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            RAL+RR G T ++  + + VGDL +DEDS EV RAGE +SLT+TEFELLRF+M N +RVL
Sbjct  131  RALMRRAGATRIEEHSVIHVGDLTMDEDSREVRRAGEEISLTATEFELLRFLMRNPRRVL  190

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVWSYDFGG++N+VELYISYLRKKID GREPMIHT+RGAGYVLK A
Sbjct  191  SKAQILDRVWSYDFGGQANVVELYISYLRKKIDAGREPMIHTMRGAGYVLKAA  243


>gi|345000963|ref|YP_004803817.1| winged helix family two component transcriptional regulator [Streptomyces 
sp. SirexAA-E]
 gi|344316589|gb|AEN11277.1| two component transcriptional regulator, winged helix family 
[Streptomyces sp. SirexAA-E]
Length=246

 Score =  337 bits (864),  Expect = 9e-91, Method: Compositional matrix adjust.
 Identities = 165/231 (72%), Positives = 191/231 (83%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R D  PV VL+VDDE  LAE++SMALRYEGW + +AGDG+ A+ AAR  RPD V+LDVML
Sbjct  15   RPDRHPVRVLIVDDEAPLAELLSMALRYEGWEVRSAGDGAEALRAARDFRPDAVILDVML  74

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL VL +LR E P +PVL LTA+DAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  75   PDMDGLTVLGRLRREAPDVPVLFLTARDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  134

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S + LVVGDLVLDEDSHEV R  + + LT+TEFELLRF+M N +RVLSK
Sbjct  135  LIRRSGTAVARSESTLVVGDLVLDEDSHEVSRGDDSIHLTATEFELLRFLMRNPRRVLSK  194

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVW+YDFGG++N+VELYISYLRKKID GR PMIHT RGAGY++KP 
Sbjct  195  AQILDRVWNYDFGGQANVVELYISYLRKKIDAGRSPMIHTRRGAGYLIKPG  245


>gi|297158650|gb|ADI08362.1| two-component system response regulator [Streptomyces bingchenggensis 
BCW-1]
Length=245

 Score =  337 bits (863),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 163/231 (71%), Positives = 192/231 (84%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  LA+++SMALRYEGW + TAG+G+ A+   R  RPD V+LD+ML
Sbjct  14   RPDGSPVRVLVVDDESALADLLSMALRYEGWEVRTAGNGAEALRITRELRPDAVLLDIML  73

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL +L ++R+E P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RLR 
Sbjct  74   PDMDGLTLLGRVRNELPEVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLRG  133

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            LLRR+G     S + L VGDLVLDEDSHEV RAG+ + LT+TEFELLR++M N +RVLSK
Sbjct  134  LLRRSGAAAARSESLLTVGDLVLDEDSHEVSRAGQEIHLTATEFELLRYLMRNPRRVLSK  193

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GR PMIHT RGAGY++KP 
Sbjct  194  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGRSPMIHTRRGAGYLIKPG  244


>gi|159037874|ref|YP_001537127.1| two component transcriptional regulator [Salinispora arenicola 
CNS-205]
 gi|157916709|gb|ABV98136.1| two component transcriptional regulator, winged helix family 
[Salinispora arenicola CNS-205]
Length=248

 Score =  337 bits (863),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 164/233 (71%), Positives = 194/233 (84%), Gaps = 1/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            +RR DGQPV VLVVDDEP L +++SMALRYEGW + TAG+G +A++ AR+ +PD VVLDV
Sbjct  14   LRRPDGQPVRVLVVDDEPTLTDLLSMALRYEGWQVRTAGNGMAALSTARQFQPDAVVLDV  73

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD+ G  VL +LR   P +PVL LTA+DAVEDR+AGLT GGDDYVTKPFS+EEV+ RL
Sbjct  74   MLPDLDGFAVLRRLREVAPTVPVLFLTARDAVEDRVAGLTVGGDDYVTKPFSLEEVIARL  133

Query  121  RALLRRTGVT-TVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRV  179
            RALLRR+G        A L VGDL LDEDSHEV R G+ ++LT+TEFELLR++M N +RV
Sbjct  134  RALLRRSGFAIAARHEAVLTVGDLSLDEDSHEVSRDGQLINLTATEFELLRYLMRNPRRV  193

Query  180  LSKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKP  232
            LSKAQILDRVW+YDFGG++N+VELYISYLRKKID GR PMIHTLRGAGYVLKP
Sbjct  194  LSKAQILDRVWNYDFGGQANVVELYISYLRKKIDAGRAPMIHTLRGAGYVLKP  246


>gi|329938744|ref|ZP_08288140.1| two component system response regulator [Streptomyces griseoaurantiacus 
M045]
 gi|329302235|gb|EGG46127.1| two component system response regulator [Streptomyces griseoaurantiacus 
M045]
Length=249

 Score =  337 bits (863),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 166/231 (72%), Positives = 189/231 (82%), Gaps = 0/231 (0%)

Query  3    RADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDVML  62
            R DG PV VLVVDDE  + E++SMALRYEGW I +AGDG  A+ AAR  RPD VVLD+ML
Sbjct  17   RPDGSPVRVLVVDDELSITELLSMALRYEGWRIRSAGDGQGAVRAAREFRPDAVVLDLML  76

Query  63   PDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRLRA  122
            PDM GL  L +LR E P +PVL LTAKDA EDRIAGLTAGGDDYVTKPF +E+VV RLR 
Sbjct  77   PDMDGLSALGRLRRELPDVPVLFLTAKDAAEDRIAGLTAGGDDYVTKPFGVEDVVARLRG  136

Query  123  LLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVLSK  182
            L+RR+G     S A LVVGDL+LDEDSHEV R G  + LT+TEFELLRF+M N +RVLSK
Sbjct  137  LIRRSGAADRRSDAVLVVGDLILDEDSHEVSRGGTDIHLTATEFELLRFLMRNPRRVLSK  196

Query  183  AQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            AQILDRVWSYDFGG++N+VELYISYLR+KID GREPMIHT RGAGY++KPA
Sbjct  197  AQILDRVWSYDFGGQANVVELYISYLRRKIDAGREPMIHTRRGAGYLIKPA  247


>gi|328883819|emb|CCA57058.1| putative two-component system response regulator [Streptomyces 
venezuelae ATCC 10712]
Length=247

 Score =  337 bits (863),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 163/233 (70%), Positives = 194/233 (84%), Gaps = 0/233 (0%)

Query  1    MRRADGQPVTVLVVDDEPVLAEMVSMALRYEGWNITTAGDGSSAIAAARRQRPDVVVLDV  60
            M RADG  V VLVVDDE  LAE++SMALRYEGW + +AGDG++A+ +AR  RPD V+LD+
Sbjct  14   MLRADGTAVRVLVVDDEASLAELLSMALRYEGWQVRSAGDGAAALRSAREFRPDAVILDI  73

Query  61   MLPDMSGLDVLHKLRSENPGLPVLLLTAKDAVEDRIAGLTAGGDDYVTKPFSIEEVVLRL  120
            MLPD+ GL +L ++R E P +PVL LTAKDAVEDRIAGLTAGGDDYVTKPFS+EEVV RL
Sbjct  74   MLPDVDGLSLLGRIRRELPDVPVLFLTAKDAVEDRIAGLTAGGDDYVTKPFSLEEVVARL  133

Query  121  RALLRRTGVTTVDSGAQLVVGDLVLDEDSHEVMRAGEPVSLTSTEFELLRFMMHNSKRVL  180
            R L+RR+G     S + LVVGDL LDEDSHEV R G+ + LT+TEFELLR++M N +RVL
Sbjct  134  RGLIRRSGAALARSESLLVVGDLTLDEDSHEVTRGGDSIHLTATEFELLRYLMRNPRRVL  193

Query  181  SKAQILDRVWSYDFGGRSNIVELYISYLRKKIDNGREPMIHTLRGAGYVLKPA  233
            SKAQILDRVWSYDFGG++N+VELYISYLR+KID GR PMIHT RGAGY++KP 
Sbjct  194  SKAQILDRVWSYDFGGQANVVELYISYLRRKIDAGRAPMIHTRRGAGYLIKPG  246



Lambda     K      H
   0.320    0.137    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 313223274342


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40