BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3767c

Length=314
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610903|ref|NP_218284.1|  hypothetical protein Rv3767c [Mycob...   628    3e-178
gi|340628737|ref|YP_004747189.1|  hypothetical protein MCAN_37871...   598    5e-169
gi|118463666|ref|YP_879590.1|  methyltransferase, putative, famil...   487    8e-136
gi|41406354|ref|NP_959190.1|  hypothetical protein MAP0256 [Mycob...   484    8e-135
gi|254773310|ref|ZP_05214826.1|  methyltransferase, putative, fam...   483    1e-134
gi|254822469|ref|ZP_05227470.1|  methyltransferase, putative, fam...   483    2e-134
gi|296166892|ref|ZP_06849309.1|  methyltransferase [Mycobacterium...   475    4e-132
gi|240168533|ref|ZP_04747192.1|  O-methyltransferase [Mycobacteri...   468    4e-130
gi|342860021|ref|ZP_08716673.1|  methyltransferase, putative, fam...   464    9e-129
gi|118619535|ref|YP_907867.1|  O-methyltransferase [Mycobacterium...   459    3e-127
gi|183985291|ref|YP_001853582.1|  O-methyltransferase [Mycobacter...   456    2e-126
gi|41410176|ref|NP_963012.1|  hypothetical protein MAP4078 [Mycob...   368    6e-100
gi|254776990|ref|ZP_05218506.1|  methyltransferase, putative, fam...   367    2e-99 
gi|118466587|ref|YP_883688.1|  methyltransferase, putative, famil...   364    1e-98 
gi|342858892|ref|ZP_08715546.1|  methyltransferase, putative, fam...   363    2e-98 
gi|296168386|ref|ZP_06850291.1|  methyltransferase [Mycobacterium...   353    2e-95 
gi|240169389|ref|ZP_04748048.1|  methyltransferase, putative, fam...   350    2e-94 
gi|342858891|ref|ZP_08715545.1|  methyltransferase, putative, fam...   348    9e-94 
gi|183980976|ref|YP_001849267.1|  hypothetical protein MMAR_0955 ...   345    6e-93 
gi|118464744|ref|YP_883687.1|  methyltransferase, putative, famil...   342    4e-92 
gi|254776989|ref|ZP_05218505.1|  methyltransferase, putative, fam...   341    9e-92 
gi|336460602|gb|EGO39495.1|  methyltransferase, putative, TIGR000...   341    1e-91 
gi|118616499|ref|YP_904831.1|  hypothetical protein MUL_0706 [Myc...   340    1e-91 
gi|254823499|ref|ZP_05228500.1|  methyltransferase, putative, fam...   322    4e-86 
gi|221222989|sp|Q73SJ4.2|Y4079_MYCPA  RecName: Full=Putative S-ad...   319    3e-85 
gi|118466717|ref|YP_881767.1|  methyltransferase [Mycobacterium a...   318    8e-85 
gi|254819983|ref|ZP_05224984.1|  methyltransferase [Mycobacterium...   317    1e-84 
gi|169630965|ref|YP_001704614.1|  hypothetical protein MAB_3886c ...   294    2e-77 
gi|118467600|ref|YP_884510.1|  methyltransferase [Mycobacterium s...   274    1e-71 
gi|296167737|ref|ZP_06849954.1|  methyltransferase [Mycobacterium...   274    1e-71 
gi|183981610|ref|YP_001849901.1|  O-methyltransferase [Mycobacter...   266    4e-69 
gi|118464245|ref|YP_883578.1|  methyltransferase, putative, famil...   258    6e-67 
gi|41410287|ref|NP_963123.1|  hypothetical protein MAP4189c [Myco...   257    1e-66 
gi|254776879|ref|ZP_05218395.1|  methyltransferase, putative, fam...   257    2e-66 
gi|145221338|ref|YP_001132016.1|  putative methyltransferase [Myc...   256    3e-66 
gi|315441778|ref|YP_004074657.1|  methyltransferase, , TIGR00027 ...   255    5e-66 
gi|296167339|ref|ZP_06849741.1|  methyltransferase [Mycobacterium...   254    2e-65 
gi|342859420|ref|ZP_08716074.1|  methyltransferase, putative, fam...   253    3e-65 
gi|145225601|ref|YP_001136279.1|  putative methyltransferase [Myc...   253    4e-65 
gi|333988734|ref|YP_004521348.1|  O-methyltransferase [Mycobacter...   250    2e-64 
gi|317509168|ref|ZP_07966792.1|  O-methyltransferase [Segniliparu...   249    4e-64 
gi|169631681|ref|YP_001705330.1|  hypothetical protein MAB_4607c ...   249    5e-64 
gi|296395198|ref|YP_003660082.1|  methyltransferase [Segniliparus...   248    6e-64 
gi|317509171|ref|ZP_07966795.1|  O-methyltransferase [Segniliparu...   248    8e-64 
gi|118473880|ref|YP_885025.1|  methyltransferase [Mycobacterium s...   247    2e-63 
gi|254822359|ref|ZP_05227360.1|  methyltransferase, putative, fam...   246    3e-63 
gi|108797069|ref|YP_637266.1|  hypothetical protein Mmcs_0088 [My...   246    3e-63 
gi|296168585|ref|ZP_06850389.1|  methyltransferase [Mycobacterium...   246    3e-63 
gi|342861820|ref|ZP_08718465.1|  methyltransferase, putative, fam...   246    4e-63 
gi|118470302|ref|YP_885861.1|  methyltransferase, , family protei...   245    5e-63 


>gi|15610903|ref|NP_218284.1| hypothetical protein Rv3767c [Mycobacterium tuberculosis H37Rv]
 gi|15843387|ref|NP_338424.1| hypothetical protein MT3874 [Mycobacterium tuberculosis CDC1551]
 gi|31794937|ref|NP_857430.1| hypothetical protein Mb3793c [Mycobacterium bovis AF2122/97]
 82 more sequence titles
 Length=314

 Score =  628 bits (1620),  Expect = 3e-178, Method: Compositional matrix adjust.
 Identities = 313/314 (99%), Positives = 314/314 (100%), Gaps = 0/314 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR
Sbjct  1    MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
            TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL
Sbjct  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP
Sbjct  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
            CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR
Sbjct  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS
Sbjct  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300

Query  301  IPPNLFVSAQRATS  314
            IPPNLFVSAQRATS
Sbjct  301  IPPNLFVSAQRATS  314


>gi|340628737|ref|YP_004747189.1| hypothetical protein MCAN_37871 [Mycobacterium canettii CIPT 
140010059]
 gi|340006927|emb|CCC46118.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=314

 Score =  598 bits (1541),  Expect = 5e-169, Method: Compositional matrix adjust.
 Identities = 303/314 (97%), Positives = 307/314 (98%), Gaps = 0/314 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDG+WSMY   
Sbjct  1    MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGVWSMYAKA  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
            T  AGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLA ADAGVRQ+VILASGLDSRAWRL
Sbjct  61   TPRAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLAAADAGVRQIVILASGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP
Sbjct  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
            CAW AEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPER+RRQRADMRRMR
Sbjct  181  CAWSAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERLRRQRADMRRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS
Sbjct  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300

Query  301  IPPNLFVSAQRATS  314
            IPPNLFVSAQRATS
Sbjct  301  IPPNLFVSAQRATS  314


>gi|118463666|ref|YP_879590.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
 gi|221222908|sp|A0Q9K2.1|Y301_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_0301
 gi|118164953|gb|ABK65850.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
Length=314

 Score =  487 bits (1254),  Expect = 8e-136, Method: Compositional matrix adjust.
 Identities = 244/311 (79%), Positives = 274/311 (89%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW IT+SVGATALGVAAARAAETES+NPLI+DPFARIFVDAAG G+WS+Y + 
Sbjct  1    MPRTDNDSWDITQSVGATALGVAAARAAETESENPLISDPFARIFVDAAGKGMWSIYADP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LL  A DL+PDLR  +Q MIDFMA RTAFFDE+FLA ADAGVRQVVILA+GLD+R+WRL
Sbjct  61   ALLTKADDLEPDLRGRLQLMIDFMATRTAFFDEFFLAAADAGVRQVVILAAGLDARSWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQPKVL+FKS TLR+HGAQP ++LVNVPIDLRQDWPKALQ+AGFD S+P
Sbjct  121  PWPDGTVVYELDQPKVLDFKSTTLREHGAQPKAELVNVPIDLRQDWPKALQEAGFDASRP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
              W AEGLVRYLPA+AQDLLFERIDALS PGS LASNVP +GF DP+R+ RQR DMRRMR
Sbjct  181  AVWSAEGLVRYLPAQAQDLLFERIDALSVPGSRLASNVPDSGFTDPDRLARQREDMRRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAAKLV+ EI+D DDLWY E+RT V  WLRERGWDVSTAT  EL+ARYGRSIP   +DS
Sbjct  241  AAAAKLVDAEITDFDDLWYPEERTPVDSWLRERGWDVSTATFAELMARYGRSIPQGAQDS  300

Query  301  IPPNLFVSAQR  311
            +PP L+VSAQR
Sbjct  301  MPPTLYVSAQR  311


>gi|41406354|ref|NP_959190.1| hypothetical protein MAP0256 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|81415179|sp|Q745R0.1|Y256_MYCPA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAP_0256
 gi|41394702|gb|AAS02573.1| hypothetical protein MAP_0256 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336460745|gb|EGO39633.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=314

 Score =  484 bits (1245),  Expect = 8e-135, Method: Compositional matrix adjust.
 Identities = 242/311 (78%), Positives = 274/311 (89%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW IT+SVGATALGVAAARAAETES+NPLI+DPFARIFV+AAG G+WS+Y + 
Sbjct  1    MPRTDNDSWDITQSVGATALGVAAARAAETESENPLISDPFARIFVEAAGKGMWSIYADP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LL  A DL+PDLR  +Q MIDFMA RTAFFDE+FLA ADAGVRQVVILA+GLD+R+WRL
Sbjct  61   ALLTKADDLEPDLRGRLQLMIDFMATRTAFFDEFFLAAADAGVRQVVILAAGLDARSWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQPKVL+FKS TLR+HGAQP ++LVNVPIDLRQDWPKALQ+AGFD S+P
Sbjct  121  PWPDGTVVYELDQPKVLDFKSTTLREHGAQPKAELVNVPIDLRQDWPKALQEAGFDASRP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
              W AEGLVRYLPA+AQDLLFERIDALS PGS LASNVP +GF DP+R+ RQR DMRRMR
Sbjct  181  AVWSAEGLVRYLPAQAQDLLFERIDALSAPGSRLASNVPDSGFTDPDRLARQREDMRRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAAKLV+ EI+D DDLWY E+RT V  WLRERGWDVSTAT  EL+ARYGRSIP   +DS
Sbjct  241  AAAAKLVDAEITDFDDLWYPEERTPVDSWLRERGWDVSTATFAELMARYGRSIPQGAQDS  300

Query  301  IPPNLFVSAQR  311
            +PP L+VSA+R
Sbjct  301  MPPTLYVSARR  311


>gi|254773310|ref|ZP_05214826.1| methyltransferase, putative, family protein [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=314

 Score =  483 bits (1243),  Expect = 1e-134, Method: Compositional matrix adjust.
 Identities = 241/311 (78%), Positives = 273/311 (88%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW IT+SVGATALGVAAARAAETES+NPLI+DPFARIFV+AAG G+WS+Y + 
Sbjct  1    MPRTDNDSWDITQSVGATALGVAAARAAETESENPLISDPFARIFVEAAGKGMWSIYADP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LL  A DL+PDLR  +Q MIDFMA RTAFFDE+FLA ADAGVRQVVILA+GLD+R+WRL
Sbjct  61   ALLTKADDLEPDLRGRLQLMIDFMATRTAFFDEFFLAAADAGVRQVVILAAGLDARSWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQPKVL+FKS TLR+HGAQP ++LVNVPIDLRQDWPKALQ+AGFD S+P
Sbjct  121  PWPDGTVVYELDQPKVLDFKSTTLREHGAQPKAELVNVPIDLRQDWPKALQEAGFDASRP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
              W AEGLVRYLPA+AQDLLFERIDALS PGS LASNVP +GF DP+R+ RQR DMRRMR
Sbjct  181  AVWSAEGLVRYLPAQAQDLLFERIDALSVPGSRLASNVPDSGFTDPDRLARQREDMRRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAAKLV+ EI+D DDLWY E+RT V  WLRERGWDV TAT  EL+ARYGRS+P   +DS
Sbjct  241  AAAAKLVDAEITDFDDLWYPEERTPVDSWLRERGWDVETATFAELMARYGRSVPQGAQDS  300

Query  301  IPPNLFVSAQR  311
            +PP L+VSAQR
Sbjct  301  MPPTLYVSAQR  311


>gi|254822469|ref|ZP_05227470.1| methyltransferase, putative, family protein [Mycobacterium intracellulare 
ATCC 13950]
Length=314

 Score =  483 bits (1243),  Expect = 2e-134, Method: Compositional matrix adjust.
 Identities = 240/311 (78%), Positives = 272/311 (88%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW IT+SVGATALGVAAARAAETESDNPLI DPFAR+FVDAAG+G+WS+Y N 
Sbjct  1    MPRTDNDSWEITQSVGATALGVAAARAAETESDNPLIKDPFARVFVDAAGEGMWSIYANP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LLA A D++PDLRA +Q M+DFMA RTAFFDE+FL  ADAGVRQVVILA+GLD+R+WRL
Sbjct  61   ALLAKAADIEPDLRARLQLMVDFMATRTAFFDEFFLGAADAGVRQVVILAAGLDARSWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQPKVLEFKS TLR+HGA+P +QLVNVPIDLRQDWPKAL++AGFD S+P
Sbjct  121  PWPDGTVVYELDQPKVLEFKSNTLREHGAEPTAQLVNVPIDLRQDWPKALREAGFDASRP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
              W AEGLVRYLPA+AQDLLFERID+LS  GSWLASNVP +GF DP+R++RQR DMRRMR
Sbjct  181  AVWSAEGLVRYLPAQAQDLLFERIDSLSAEGSWLASNVPESGFTDPDRVQRQREDMRRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAAKLV  EI+D DDLWY E+RT V  WLR RGWDV+TAT  EL+ARY R IP   EDS
Sbjct  241  AAAAKLVNAEITDFDDLWYPEERTPVDGWLRGRGWDVTTATFAELMARYDRRIPQGAEDS  300

Query  301  IPPNLFVSAQR  311
            +PP L+VSAQR
Sbjct  301  MPPTLYVSAQR  311


>gi|296166892|ref|ZP_06849309.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897769|gb|EFG77358.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=313

 Score =  475 bits (1222),  Expect = 4e-132, Method: Compositional matrix adjust.
 Identities = 235/311 (76%), Positives = 271/311 (88%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW IT+SVGATALGVAAARAAETES+NPLINDPFAR+FVDAAG+G+WS+Y + 
Sbjct  1    MPRTDNDSWDITQSVGATALGVAAARAAETESENPLINDPFARVFVDAAGEGMWSIYADP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LLA A +L+PD+R+ IQ MIDFMA RTAFFDE+FL  AD+GVRQVVILA+GLD+R WRL
Sbjct  61   QLLAKAMELEPDVRSRIQLMIDFMATRTAFFDEFFLGAADSGVRQVVILAAGLDARTWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQPKVL+FKS TLR+HGAQP + LVNVP+DLRQDWPKALQ+AGFD SKP
Sbjct  121  PWPDGTVVYELDQPKVLDFKSDTLRRHGAQPKAGLVNVPVDLRQDWPKALQEAGFDASKP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AW AEGLVRYLPA+AQDLLFER+ +LS  GSWLASNVPGAGF DP  + RQR DM+R+R
Sbjct  181  AAWSAEGLVRYLPAQAQDLLFERVHSLSAQGSWLASNVPGAGFTDPGLVTRQREDMKRLR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAAKLV+ EI+D DDLWYAE+RT V  WLRE GWDV+T T  EL+ARYGRS+    ED+
Sbjct  241  AAAAKLVDAEITDFDDLWYAEERTPVDGWLREHGWDVTTTTFAELMARYGRSVAQGVEDT  300

Query  301  IPPNLFVSAQR  311
            +PP L+VSAQR
Sbjct  301  MPPTLYVSAQR  311


>gi|240168533|ref|ZP_04747192.1| O-methyltransferase [Mycobacterium kansasii ATCC 12478]
Length=314

 Score =  468 bits (1205),  Expect = 4e-130, Method: Compositional matrix adjust.
 Identities = 233/311 (75%), Positives = 271/311 (88%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW ITESVGATALGVAAARAAETES+NPLI DPFAR+FVDAAG+GIWS + + 
Sbjct  1    MPRTDNDSWDITESVGATALGVAAARAAETESENPLIRDPFARVFVDAAGEGIWSAFADP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LLA   D +P +R+ ++ M+DFMA RTAFFDE+FL  ADAGVRQVVILA+GLD+RAWRL
Sbjct  61   RLLAQVADSEPGVRSRVRAMVDFMATRTAFFDEFFLGAADAGVRQVVILAAGLDARAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWP GTVVYELDQPKVL+FK+ATLR+HGA+P ++LVNVPIDLRQDWP ALQ+AGFD SKP
Sbjct  121  PWPGGTVVYELDQPKVLDFKTATLRRHGARPTAELVNVPIDLRQDWPTALQEAGFDASKP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
            CAW AEGL+RYLPA AQDLLF+RIDA S  GSWLA NVP AGFLDP+ +RRQR DM+R+R
Sbjct  181  CAWSAEGLLRYLPATAQDLLFDRIDAQSTAGSWLACNVPAAGFLDPDLVRRQREDMQRIR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAA+LV+ E +D+DDLWYAE+RTAVA+WL ERGW VS  T+ E+LARYGRS+P   EDS
Sbjct  241  AAAARLVKVEATDLDDLWYAEERTAVADWLVERGWQVSAQTMTEVLARYGRSVPSDLEDS  300

Query  301  IPPNLFVSAQR  311
            +PP LFVSAQR
Sbjct  301  MPPTLFVSAQR  311


>gi|342860021|ref|ZP_08716673.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
 gi|342132399|gb|EGT85628.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
Length=314

 Score =  464 bits (1194),  Expect = 9e-129, Method: Compositional matrix adjust.
 Identities = 240/311 (78%), Positives = 273/311 (88%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW IT+SVGATALGVAAARAAETES+NPLINDPFAR+FVDAAG G+WS+Y + 
Sbjct  1    MPRTDNDSWEITQSVGATALGVAAARAAETESENPLINDPFARVFVDAAGQGMWSIYADP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LLA A DL+PDLR  +Q M+DFMA RTAFFDE+FL  ADAGVRQVVILA+GLD+R+WRL
Sbjct  61   ALLAKAGDLEPDLRDRLQLMVDFMATRTAFFDEFFLGAADAGVRQVVILAAGLDARSWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQPKVLEFKS TLR+HGAQP +QLVNVPIDLRQDWPKALQ+AGFD SKP
Sbjct  121  PWPDGTVVYELDQPKVLEFKSKTLREHGAQPKAQLVNVPIDLRQDWPKALQEAGFDVSKP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
              W AEGLVRYLPA+AQDLLFERID+LS  GSWLASNVP  GF DP+R++RQR DMRRMR
Sbjct  181  AVWSAEGLVRYLPAQAQDLLFERIDSLSSRGSWLASNVPAPGFTDPDRVQRQRDDMRRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAAA+L+  EI+D DDLWYAE+RT V  WLR+ GWDV+TA+  EL+ARYGRS+P   EDS
Sbjct  241  AAAAELINAEITDFDDLWYAEERTPVDAWLRDHGWDVATASFAELMARYGRSVPQGAEDS  300

Query  301  IPPNLFVSAQR  311
            +PP L+VSAQR
Sbjct  301  MPPTLYVSAQR  311


>gi|118619535|ref|YP_907867.1| O-methyltransferase [Mycobacterium ulcerans Agy99]
 gi|221222923|sp|A0PVM7.1|Y4402_MYCUA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MUL_4402
 gi|118571645|gb|ABL06396.1| O-methyltransferase [Mycobacterium ulcerans Agy99]
Length=314

 Score =  459 bits (1181),  Expect = 3e-127, Method: Compositional matrix adjust.
 Identities = 230/311 (74%), Positives = 261/311 (84%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW ITESVGATALGVAAARAAETES+NPLI DPFAR+FVDAAGDG+WSM+ N 
Sbjct  1    MPRTDNDSWTITESVGATALGVAAARAAETESENPLIEDPFARVFVDAAGDGMWSMFANP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LLAGA +++  + A ++QMIDFMA RTAFFDE+FL  ADAGVRQVVILASGLDSRAWRL
Sbjct  61   ALLAGAPEIESQVGARVRQMIDFMATRTAFFDEFFLGAADAGVRQVVILASGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQP+VLEFKSATLRQHGA+P +QL+N+PIDLRQDWP AL  +GFD SKP
Sbjct  121  PWPDGTVVYELDQPRVLEFKSATLRQHGARPTAQLMNIPIDLRQDWPAALLDSGFDASKP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AW AEGLVRYLPARAQDLLFERID LS  GSWLA+NVP  GFLDP+ +RRQ  +M+RMR
Sbjct  181  TAWSAEGLVRYLPARAQDLLFERIDTLSPAGSWLATNVPQGGFLDPDLVRRQHEEMQRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAA +LVE ++  V+DLWYAE+RT VA+WL E GW  S  T  ELL RYGR +P   E  
Sbjct  241  AAAGRLVEIQMPAVEDLWYAEERTPVADWLGEHGWRASATTSAELLTRYGRPVPDDAEGP  300

Query  301  IPPNLFVSAQR  311
            +PP LFVSA R
Sbjct  301  VPPTLFVSAHR  311


>gi|183985291|ref|YP_001853582.1| O-methyltransferase [Mycobacterium marinum M]
 gi|221222975|sp|B2HLJ5.1|Y5323_MYCMM RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MMAR_5323
 gi|183178617|gb|ACC43727.1| O-methyltransferase [Mycobacterium marinum M]
Length=314

 Score =  456 bits (1173),  Expect = 2e-126, Method: Compositional matrix adjust.
 Identities = 229/311 (74%), Positives = 259/311 (84%), Gaps = 0/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTDNDSW ITESVGATALGVAAARAAETES+NPLI DPFAR+FVDAAGDG+WSM+ N 
Sbjct  1    MPRTDNDSWTITESVGATALGVAAARAAETESENPLIEDPFARVFVDAAGDGMWSMFANP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             LLAGA +++  + A ++QMIDFMA RTAFFDE+FL  AD GVRQVVILASGLDSRAWRL
Sbjct  61   ALLAGAPEIESQVGARVRQMIDFMATRTAFFDEFFLGAADTGVRQVVILASGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGTVVYELDQP+VLEFKSATLRQHGA+P +QLVN+PIDLRQDWP AL  +GFD SKP
Sbjct  121  PWPDGTVVYELDQPRVLEFKSATLRQHGARPTAQLVNIPIDLRQDWPAALLDSGFDASKP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AW AEGLVRYLPARAQDLLFERID LS  GSWLA+NVP  GF DP+ +RRQ  +M+RMR
Sbjct  181  TAWSAEGLVRYLPARAQDLLFERIDTLSPAGSWLATNVPQEGFSDPDLVRRQHEEMQRMR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
            AAA +LVE ++  V+DLWYAE+RT VA+WL E GW  S  T  ELL RYGR +P   E  
Sbjct  241  AAAGRLVEIQMPAVEDLWYAEERTPVADWLGEHGWRASATTSAELLTRYGRPVPDDAEGP  300

Query  301  IPPNLFVSAQR  311
            +PP LFVSA R
Sbjct  301  VPPTLFVSAHR  311


>gi|41410176|ref|NP_963012.1| hypothetical protein MAP4078 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|81413008|sp|Q73SJ5.1|Y4078_MYCPA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAP_4078
 gi|41399010|gb|AAS06628.1| hypothetical protein MAP_4078 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336460603|gb|EGO39496.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=320

 Score =  368 bits (945),  Expect = 6e-100, Method: Compositional matrix adjust.
 Identities = 191/312 (62%), Positives = 233/312 (75%), Gaps = 1/312 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTD+DSW ITESVGATALGVAAARAAETES+NPLI+DPFAR+F+DAAGDG+W+ +   
Sbjct  1    MPRTDDDSWEITESVGATALGVAAARAAETESENPLISDPFARVFLDAAGDGMWNWFAAP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             L A   + +PDL+  +Q M+D+MAARTAFFD +FLA   AGVRQVVILA+GLDSRAWRL
Sbjct  61   NLPAQIAEAEPDLKPRMQGMVDYMAARTAFFDNFFLAATHAGVRQVVILAAGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            P+ DGT VYELDQP+VLEFK+ TL +HGA+P   LV+VP+DLR DWP AL++AGFD   P
Sbjct  121  PFEDGTTVYELDQPRVLEFKATTLAEHGARPTCHLVSVPVDLRHDWPAALRQAGFDAHAP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AW AEGL+ +LPA AQ LLFER+  L+ PGS +A   PG  F+D     RQR  M+R+R
Sbjct  181  SAWSAEGLLPFLPAAAQQLLFERVQTLAAPGSRIAVEAPGPDFIDEAARERQRQTMQRVR  240

Query  241  AAAAKLV-ETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGED  299
               A L  + +I DV DLWY E+R  V +WL   GWDV+    PEL+ARY R  PH  ED
Sbjct  241  DLMADLEPDRDIPDVQDLWYFEEREDVGDWLGRHGWDVTVTPAPELMARYDRRPPHDIED  300

Query  300  SIPPNLFVSAQR  311
            +IP   FV+AQR
Sbjct  301  AIPQTRFVAAQR  312


>gi|254776990|ref|ZP_05218506.1| methyltransferase, putative, family protein [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=320

 Score =  367 bits (941),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 191/312 (62%), Positives = 232/312 (75%), Gaps = 1/312 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTD+DSW ITESVGATALGVAAARAAETES+NPLI+DPFAR+F+DAAGDG+W+ +   
Sbjct  1    MPRTDDDSWEITESVGATALGVAAARAAETESENPLISDPFARVFLDAAGDGMWNWFAAP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             L A   + +PDL+  +Q M+D+MAARTAFFD +FLA   AGVRQVVILA+GLDSRAWRL
Sbjct  61   NLPAQIAEAEPDLKPRMQGMVDYMAARTAFFDNFFLAATRAGVRQVVILAAGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            P+ DGT VYELDQP+VLEFK+ TL +HGA+P   LV+VP+DLR DWP AL++AGFD   P
Sbjct  121  PFEDGTTVYELDQPRVLEFKATTLAEHGARPTCHLVSVPVDLRHDWPAALRQAGFDAHAP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AW AEGL+ +LPA AQ LLFER+  L+ PGS +A   PG  FLD     RQR  M+R+R
Sbjct  181  SAWSAEGLLPFLPAAAQQLLFERVQTLAAPGSRIAVEAPGPDFLDEAARERQRQTMQRVR  240

Query  241  AAAAKLV-ETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGED  299
               A L  + +I DV DLWY E+R  V +WL   GWDV+    PEL+ARY R  PH  ED
Sbjct  241  DLMADLEPDRDIPDVQDLWYFEEREDVGDWLGRHGWDVTVTPAPELMARYDRRPPHDIED  300

Query  300  SIPPNLFVSAQR  311
            + P   FV+AQR
Sbjct  301  ATPQTRFVAAQR  312


>gi|118466587|ref|YP_883688.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
 gi|221222931|sp|A0QLA0.1|Y4558_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_4558
 gi|118167874|gb|ABK68771.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
Length=320

 Score =  364 bits (934),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 190/312 (61%), Positives = 232/312 (75%), Gaps = 1/312 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTD+DSW ITESVGATALGVAAARAAETES+NPLI+DPFAR+F+DAAGDG+W+ +   
Sbjct  1    MPRTDDDSWEITESVGATALGVAAARAAETESENPLISDPFARVFLDAAGDGMWNWFAAP  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             L A   + +PDL+  +Q M+D+MAARTAFFD +FLA   AGVRQVVILA+GLDSRAWRL
Sbjct  61   NLPAQIAEAEPDLKPRMQGMVDYMAARTAFFDNFFLAATRAGVRQVVILAAGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            P+ DGT VYELDQP+VLEFK+ TL ++GA+P   LV+VP+DLR DWP AL++AGFD   P
Sbjct  121  PFEDGTTVYELDQPRVLEFKATTLAEYGARPTCHLVSVPVDLRHDWPAALRQAGFDAHAP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AW AEGL+ +LPA AQ LLFER+  L+ PGS +A   PG  FLD     RQR  M+R+R
Sbjct  181  SAWSAEGLLPFLPAAAQQLLFERVQTLAAPGSRIAVEAPGPDFLDEAARERQRQTMQRVR  240

Query  241  AAAAKLV-ETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGED  299
               A L  + +I DV DLWY E+R  V +WL   GWDV+    PEL+ARY R  PH  ED
Sbjct  241  DLMADLEPDRDIPDVQDLWYFEEREDVGDWLGRHGWDVTVTPAPELMARYDRRPPHDIED  300

Query  300  SIPPNLFVSAQR  311
            + P   FV+AQR
Sbjct  301  ATPQTRFVAAQR  312


>gi|342858892|ref|ZP_08715546.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
 gi|342133133|gb|EGT86336.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
Length=316

 Score =  363 bits (932),  Expect = 2e-98, Method: Compositional matrix adjust.
 Identities = 189/310 (61%), Positives = 230/310 (75%), Gaps = 1/310 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTDNDSW ITESVGATALGVAAARAAETES+NPLI+DPFAR+F+ AAG G+W  +    L
Sbjct  3    RTDNDSWEITESVGATALGVAAARAAETESENPLISDPFARVFLQAAGKGVWDWFAAPNL  62

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
             A   ++DPDL+  +Q M+D+MAARTAFFD +FL    AGVRQVVILA+GLDSRAWRLPW
Sbjct  63   PAQIAEIDPDLKPRMQGMVDYMAARTAFFDRFFLDATAAGVRQVVILAAGLDSRAWRLPW  122

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            PDGT VYELDQP+VL+FK++TLR  GAQP  +LV+VP+DLR DWP ALQ+AGFD   P  
Sbjct  123  PDGTTVYELDQPRVLDFKASTLRDKGAQPTCELVSVPVDLRHDWPSALQRAGFDAEAPSV  182

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ +LPA AQ+LLF+R+ AL+ PGS +A   PG  FLD     RQR  M+R+R  
Sbjct  183  WSAEGLLPFLPAAAQELLFDRVQALATPGSRIAVEAPGPDFLDEGARARQRQTMQRVRDL  242

Query  243  AAKLV-ETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A+L  + +I DV DLWY E+R  V +WL   GWDV+    PEL+A Y R  P   +D+ 
Sbjct  243  MAELEPDRDIPDVQDLWYFEEREDVGDWLGRHGWDVTVTPAPELMAGYDRRPPQDIDDAT  302

Query  302  PPNLFVSAQR  311
            P  LFV+AQR
Sbjct  303  PQTLFVAAQR  312


>gi|296168386|ref|ZP_06850291.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295896733|gb|EFG76367.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=315

 Score =  353 bits (907),  Expect = 2e-95, Method: Compositional matrix adjust.
 Identities = 176/313 (57%), Positives = 228/313 (73%), Gaps = 1/313 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTDNDSW ITESVGATALGVA+ARAAET SD+PLI DPFA+IF+DAAGDG+W+ ++   L
Sbjct  3    RTDNDSWEITESVGATALGVASARAAETRSDDPLIRDPFAQIFLDAAGDGVWNWHSAPQL  62

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
                 + +P L   ++ M+ +MA+RTAFFDE+FLA   AG+RQ VILA+GLD+RAWRL W
Sbjct  63   PDEVVEAEPQLPLQMRAMVGYMASRTAFFDEFFLAATGAGIRQAVILAAGLDARAWRLGW  122

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            PDGT VYELDQP+VL+FKS+TL + GA+P    V V +DLR DWP AL++AGFDPS P  
Sbjct  123  PDGTTVYELDQPRVLDFKSSTLAERGARPTCNRVEVAVDLRHDWPTALREAGFDPSAPSV  182

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQ+LLF+R+  L+ PGS +A    G  FLDPE   ++R  M R+RA 
Sbjct  183  WSAEGLMPYLPAAAQELLFDRVHGLTAPGSRVAVEALGPKFLDPEFRAKRRERMDRVRAL  242

Query  243  AAKLV-ETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A++  + ++   D+LWY E+R  V +W R  GW V+     EL+A YGR+ P   ED++
Sbjct  243  MARVAPDRDVPRTDELWYFEEREDVGDWFRRHGWSVTVTPADELMAGYGRTAPKEVEDAV  302

Query  302  PPNLFVSAQRATS  314
            P NLFV+A+RA +
Sbjct  303  PGNLFVAAERAAT  315


>gi|240169389|ref|ZP_04748048.1| methyltransferase, putative, family protein [Mycobacterium kansasii 
ATCC 12478]
Length=318

 Score =  350 bits (897),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 180/311 (58%), Positives = 226/311 (73%), Gaps = 1/311 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTDNDSW ITESVGATALGVAAARAAET+S++PLI+DPFAR+F+DAAGDG+W+ Y+   L
Sbjct  6    RTDNDSWEITESVGATALGVAAARAAETQSEHPLIHDPFARVFLDAAGDGVWNWYSAPQL  65

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
             A     +P++   +Q MI++MA RTAFFD +FL    +G+RQ VILA+GLD+R WRLPW
Sbjct  66   PAEVLQAEPEVHLRMQAMINYMACRTAFFDTFFLEATRSGIRQAVILAAGLDARCWRLPW  125

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT VYELDQPKVLEFK++TL +HGA+P    V VP+DLRQDWPKAL++AGFD S P A
Sbjct  126  PAGTTVYELDQPKVLEFKTSTLHKHGAEPTCNRVGVPVDLRQDWPKALRQAGFDASAPSA  185

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQD+LF R+  L   GS +A    G  FLDP    ++R  M R+RA 
Sbjct  186  WSAEGLMPYLPAAAQDMLFNRVQELVVSGSRIAVEALGPDFLDPAFRAKRRERMDRVRAL  245

Query  243  AAKL-VETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             AK+  + E+   D+LWY E+R  V +WLR  GW+V+     +L+A Y R+ P   +DS 
Sbjct  246  MAKIDPQREVPSTDELWYFEERDDVGDWLRRHGWEVTVTPSAQLMAGYDRNPPKEVQDSA  305

Query  302  PPNLFVSAQRA  312
            P NLFVSA RA
Sbjct  306  PQNLFVSAVRA  316


>gi|342858891|ref|ZP_08715545.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
 gi|342133132|gb|EGT86335.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
Length=315

 Score =  348 bits (892),  Expect = 9e-94, Method: Compositional matrix adjust.
 Identities = 175/311 (57%), Positives = 223/311 (72%), Gaps = 1/311 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTDNDSW ITESVGATALGVA+ARAAET ++NPLI DPFA++F+DAAGDG+W+ ++   L
Sbjct  3    RTDNDSWEITESVGATALGVASARAAETRNENPLITDPFAQVFLDAAGDGVWNWHSAGQL  62

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
                 + +P L   +Q M+ +MA+RTAFFD++FL  A AG+RQ VILA+GLD+R+WRLPW
Sbjct  63   PDEVIEAEPTLPLQMQSMVGYMASRTAFFDKFFLDAAAAGIRQAVILAAGLDARSWRLPW  122

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P G  VYELDQ +VL+FK+ATL +HGA PA   V VP+DLRQDWP AL++AGFD S P  
Sbjct  123  PAGVTVYELDQTRVLDFKAATLAEHGAAPACNRVAVPVDLRQDWPAALRQAGFDASAPSV  182

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQDLLF+RI  L+ PGS +A    G  FLDP+   ++R  M R+R  
Sbjct  183  WSAEGLMPYLPAAAQDLLFDRIQGLTVPGSRVAVEALGPTFLDPQFRAKRRERMDRIRGL  242

Query  243  AAKL-VETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A +  + E+   D+LWY E+R  V EW    GWDV+     EL+A YGR+ P    D +
Sbjct  243  MAGVDPDREVPRTDELWYFEEREDVGEWFGRHGWDVTVTPADELMAGYGRAAPEEVRDYV  302

Query  302  PPNLFVSAQRA  312
            P NLFV+AQR+
Sbjct  303  PGNLFVAAQRS  313


>gi|183980976|ref|YP_001849267.1| hypothetical protein MMAR_0955 [Mycobacterium marinum M]
 gi|221222958|sp|B2HSF4.1|Y955_MYCMM RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MMAR_0955
 gi|183174302|gb|ACC39412.1| conserved protein [Mycobacterium marinum M]
Length=313

 Score =  345 bits (885),  Expect = 6e-93, Method: Compositional matrix adjust.
 Identities = 175/310 (57%), Positives = 223/310 (72%), Gaps = 1/310 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RT++DSW ITESVGATALGVA+ARAAET S +PLI+DPFA++F+DA GDG+W+ ++   L
Sbjct  3    RTEDDSWEITESVGATALGVASARAAETRSQHPLISDPFAQVFLDAVGDGVWNWHSAPQL  62

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
             A   +++PDL   ++ M+ +MA+RTAFFDE+FL    AG+ Q VILA+GLDSRAWRLPW
Sbjct  63   PAELLEIEPDLPLQMEAMVSYMASRTAFFDEFFLDATRAGIGQAVILAAGLDSRAWRLPW  122

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT V+ELDQP+VLEFK+ATL +HGA+PA   V V +DLRQDWP AL++AGFDPS P  
Sbjct  123  PAGTTVFELDQPRVLEFKAATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVPSV  182

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQDLLFER+  L+   S +A    G  FLDP+    + A M R+RA 
Sbjct  183  WSAEGLMPYLPAVAQDLLFERVQGLTVRASRIAVEALGPKFLDPQVRANRSARMERIRAV  242

Query  243  AAKLV-ETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A +  + EI   D+LWY E+R  V +W R   WDV+     EL+A YGR+     ED +
Sbjct  243  MAHVEPQREIPRTDELWYFEEREDVGDWFRRHDWDVTVTPSGELMAGYGRAAAAQVEDRV  302

Query  302  PPNLFVSAQR  311
            P NLFV+AQR
Sbjct  303  PTNLFVAAQR  312


>gi|118464744|ref|YP_883687.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
 gi|221222930|sp|A0QL99.1|Y4557_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_4557
 gi|118166031|gb|ABK66928.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
Length=315

 Score =  342 bits (877),  Expect = 4e-92, Method: Compositional matrix adjust.
 Identities = 173/310 (56%), Positives = 219/310 (71%), Gaps = 1/310 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTD+DSW ITESVGATALGVA+ARAAET S+NPLI DPFA++F+DAAGDG+W+ ++   L
Sbjct  5    RTDDDSWEITESVGATALGVASARAAETRSENPLIKDPFAQVFLDAAGDGVWNWHSAPQL  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
                 + +P +    Q M+ +MA+RTAFFD +FL    AG+RQ VILA+GLD+R+WRLPW
Sbjct  65   PPELIEAEPTIPLQQQAMVSYMASRTAFFDSFFLEATGAGIRQAVILAAGLDARSWRLPW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT VYELDQP+VLEFK +TL +HGAQPA   V VP+DLR DWP+AL++AGFD S P  
Sbjct  125  PAGTTVYELDQPRVLEFKESTLAEHGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSV  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQDLLF+RI  L+  GS +A    G  FLDP+   ++R  M R++A 
Sbjct  185  WSAEGLMPYLPAAAQDLLFDRIQGLTVAGSRVAVEALGPKFLDPQARAKRRERMDRIQAL  244

Query  243  AAKL-VETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A++  +  +   D+LWY E+R  V EW    GWDV      EL+A YGR  P    D +
Sbjct  245  MARIDPDRAVPRTDELWYFEEREDVGEWFGRHGWDVRVTPSDELMAGYGRPAPAEVRDFV  304

Query  302  PPNLFVSAQR  311
            P NLFV+AQR
Sbjct  305  PGNLFVAAQR  314


>gi|254776989|ref|ZP_05218505.1| methyltransferase, putative, family protein [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=315

 Score =  341 bits (874),  Expect = 9e-92, Method: Compositional matrix adjust.
 Identities = 172/310 (56%), Positives = 219/310 (71%), Gaps = 1/310 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            R+D+DSW ITESVGATALGVA+ARAAET S+NPLI DPFA++F+DAAGDG+W+ ++   L
Sbjct  5    RSDDDSWEITESVGATALGVASARAAETRSENPLIKDPFAQVFLDAAGDGVWNWHSAPQL  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
                 + +P +    Q M+ +MA+RTAFFD +FL    AG+RQ VILA+GLD+R+WRLPW
Sbjct  65   PPELIEAEPTIPLQQQAMVSYMASRTAFFDSFFLEATGAGIRQAVILAAGLDARSWRLPW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT VYELDQP+VLEFK +TL +HGAQPA   V VP+DLR DWP+AL++AGFD S P  
Sbjct  125  PAGTTVYELDQPRVLEFKESTLAEHGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSV  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQDLLF+RI  L+  GS +A    G  FLDP+   ++R  M R++A 
Sbjct  185  WSAEGLMPYLPAAAQDLLFDRIQGLTVAGSRVAVEALGPKFLDPQARAKRRERMDRIQAL  244

Query  243  AAKL-VETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A++  +  +   D+LWY E+R  V EW    GWDV      EL+A YGR  P    D +
Sbjct  245  MARIDPDRAVPRTDELWYFEEREDVGEWFGRHGWDVRVTPSDELMAGYGRPAPAEVRDFV  304

Query  302  PPNLFVSAQR  311
            P NLFV+AQR
Sbjct  305  PGNLFVAAQR  314


>gi|336460602|gb|EGO39495.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=315

 Score =  341 bits (874),  Expect = 1e-91, Method: Compositional matrix adjust.
 Identities = 172/310 (56%), Positives = 219/310 (71%), Gaps = 1/310 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            R+D+DSW ITESVGATALGVA+ARAAET S+NPLI DPFA++F+DAAGDG+W+ ++   L
Sbjct  5    RSDDDSWEITESVGATALGVASARAAETRSENPLIKDPFAQVFLDAAGDGVWNWHSAPQL  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
                 + +P +    Q M+ +MA+RTAFFD +FL    AG+RQ VILA+GLD+R+WRLPW
Sbjct  65   PPELIEAEPTIPLQQQAMVGYMASRTAFFDSFFLEATGAGIRQAVILAAGLDARSWRLPW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT VYELDQP+VLEFK +TL +HGAQPA   V VP+DLR DWP+AL++AGFD S P  
Sbjct  125  PAGTTVYELDQPRVLEFKESTLAEHGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSV  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQDLLF+RI  L+  GS +A    G  FLDP+   ++R  M R++A 
Sbjct  185  WSAEGLMPYLPAAAQDLLFDRIQGLTVAGSRVAVEALGPKFLDPQARAKRRERMDRIQAL  244

Query  243  AAKL-VETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A++  +  +   D+LWY E+R  V EW    GWDV      EL+A YGR  P    D +
Sbjct  245  MARIDPDRAVPRTDELWYFEEREDVGEWFGRHGWDVRVTPSDELMAGYGRPAPAEVRDFV  304

Query  302  PPNLFVSAQR  311
            P NLFV+AQR
Sbjct  305  PGNLFVAAQR  314


>gi|118616499|ref|YP_904831.1| hypothetical protein MUL_0706 [Mycobacterium ulcerans Agy99]
 gi|221222941|sp|A0PLZ1.1|Y706_MYCUA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MUL_0706
 gi|118568609|gb|ABL03360.1| conserved protein [Mycobacterium ulcerans Agy99]
Length=313

 Score =  340 bits (873),  Expect = 1e-91, Method: Compositional matrix adjust.
 Identities = 173/310 (56%), Positives = 222/310 (72%), Gaps = 1/310 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RT++DSW ITESVGATALGVA+ARAAET S +PLI+DPFA++F+DA GDG+W+ ++   L
Sbjct  3    RTEDDSWEITESVGATALGVASARAAETRSQHPLISDPFAQVFLDAVGDGVWNWHSAPQL  62

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
             A   +++PDL   ++ M+ +MA+RTAFFDE+FL    AG+ Q VILA+GLDSRAWRLPW
Sbjct  63   PAELLEIEPDLPLQMEAMVSYMASRTAFFDEFFLDATRAGIGQAVILAAGLDSRAWRLPW  122

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT V+ELDQP+VLEFK+ATL +HGA+PA   V V +DLRQDWP AL++AGFDPS    
Sbjct  123  PAGTTVFELDQPRVLEFKAATLAEHGAEPACGRVAVAVDLRQDWPTALRQAGFDPSVSSV  182

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQDLLFER+  L+   S +A    G  FLDP+    + A + R+RA 
Sbjct  183  WSAEGLMPYLPAVAQDLLFERVQGLTVRASRIAVEALGPKFLDPQVRANRSARIERIRAV  242

Query  243  AAKLV-ETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A +  + EI   D+LWY E+R  V +W R   WDV+     EL+A YGR+     ED +
Sbjct  243  MAHVEPQREIPRTDELWYFEEREDVGDWFRRHDWDVTVTPSGELMAGYGRAAAAQVEDRV  302

Query  302  PPNLFVSAQR  311
            P NLFV+AQR
Sbjct  303  PTNLFVAAQR  312


>gi|254823499|ref|ZP_05228500.1| methyltransferase, putative, family protein [Mycobacterium intracellulare 
ATCC 13950]
Length=315

 Score =  322 bits (825),  Expect = 4e-86, Method: Compositional matrix adjust.
 Identities = 173/310 (56%), Positives = 221/310 (72%), Gaps = 1/310 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTDNDSW ITESVGATALGVAAARAAET  +NPLI+DPFA++F+DAAGDG+W+ ++   L
Sbjct  3    RTDNDSWEITESVGATALGVAAARAAETRGENPLISDPFAQVFLDAAGDGVWNWHSAGRL  62

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
                 + +P L   +Q M+ +MA+RTAFFD +FL    AG+RQ VILA+GLD+R+WRL W
Sbjct  63   PDAVVEAEPTLPLQMQSMVGYMASRTAFFDRFFLDATAAGIRQAVILAAGLDARSWRLAW  122

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT VYELDQP+VL+FK++TL +HGAQPA   V V +DLRQDWP+AL++AGFD S P  
Sbjct  123  PAGTTVYELDQPRVLDFKASTLAEHGAQPACHRVPVAVDLRQDWPEALRQAGFDVSAPSV  182

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQ+LLFERI  L+  GS +A    G  FLDP+   R+R  M R+ A 
Sbjct  183  WSAEGLMPYLPAAAQELLFERIQGLTVSGSRVAVEALGPKFLDPQLRARRRERMDRIAAL  242

Query  243  AAKL-VETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A++  + ++   D+LWY E+R  V EW    GWDV+     EL+A YGR+      D +
Sbjct  243  MAEVDPDRQVPRTDELWYFEEREDVGEWFGRHGWDVTVTPSDELMAGYGRAAAKEVRDYV  302

Query  302  PPNLFVSAQR  311
            P NLFV+AQR
Sbjct  303  PGNLFVAAQR  312


>gi|221222989|sp|Q73SJ4.2|Y4079_MYCPA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAP_4079
Length=539

 Score =  319 bits (818),  Expect = 3e-85, Method: Compositional matrix adjust.
 Identities = 159/286 (56%), Positives = 204/286 (72%), Gaps = 1/286 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            R+D+DSW ITESVGATALGVA+ARAAET S+NPLI DPFA++F+DAAGDG+W+ ++   L
Sbjct  5    RSDDDSWEITESVGATALGVASARAAETRSENPLIKDPFAQVFLDAAGDGVWNWHSAPQL  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
                 + +P +    Q M+ +MA+RTAFFD +FL    AG+RQ VILA+GLD+R+WRLPW
Sbjct  65   PPELIEAEPTIPLQQQAMVGYMASRTAFFDSFFLEATGAGIRQAVILAAGLDARSWRLPW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT VYELDQP+VLEFK +TL +HGAQPA   V VP+DLR DWP+AL++AGFD S P  
Sbjct  125  PAGTTVYELDQPRVLEFKESTLAEHGAQPACNRVAVPVDLRHDWPEALRQAGFDASAPSV  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            W AEGL+ YLPA AQDLLF+RI  L+  GS +A    G  FLDP+   ++R  M R++A 
Sbjct  185  WSAEGLMPYLPAAAQDLLFDRIQGLTVAGSRVAVEALGPKFLDPQARAKRRERMDRIQAL  244

Query  243  AAKL-VETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLA  287
             A++  +  +   D+LWY E+R  V EW    GWDV      EL+A
Sbjct  245  MARIDPDRAVPRTDELWYFEEREDVGEWFGRHGWDVRVTPSDELMA  290


>gi|118466717|ref|YP_881767.1| methyltransferase [Mycobacterium avium 104]
 gi|221222901|sp|A0QFS9.1|Y2576_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_2576
 gi|118168004|gb|ABK68901.1| methyltransferase [Mycobacterium avium 104]
Length=313

 Score =  318 bits (814),  Expect = 8e-85, Method: Compositional matrix adjust.
 Identities = 163/311 (53%), Positives = 209/311 (68%), Gaps = 1/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            + RTDND+W I ESVGATALGVA  RAAET S +PLI+DP+A++F++AAGDGIW +Y + 
Sbjct  1    MARTDNDTWDINESVGATALGVAGGRAAETRSADPLISDPYAKLFLEAAGDGIWRVYLDD  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             L A     DP     +Q M+ + A RT FFD+YFLA A  G+RQ+VILA+GLDSRAWRL
Sbjct  61   ELPAELVGADPQFEDRMQAMLGYTACRTKFFDDYFLAAAGEGIRQIVILAAGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
             WP G VVYE+DQPKVLEFK  TL+ H   P +  V+V IDLR DWPKAL +AGFD S P
Sbjct  121  AWPAGCVVYEIDQPKVLEFKIGTLKSHAVDPIASHVSVGIDLRLDWPKALAQAGFDASAP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AW AEGL+ YL A AQ LLF+RI +LS PGS +A       F  PE   R+     R R
Sbjct  181  TAWSAEGLLPYLTADAQGLLFDRIQSLSAPGSRVAVEAFTNEFFSPESFARREEQTERYR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPE-LLARYGRSIPHSGED  299
             AA +L   +I++  +L Y E+RT V +WL+  GW V+ AT  E L+A   R++P   + 
Sbjct  241  QAAIRLGGKDITESGNLLYEEERTEVVDWLQAHGWTVTAATSAEDLMAASNRAVPAGLDA  300

Query  300  SIPPNLFVSAQ  310
            ++P ++FV  +
Sbjct  301  AVPESVFVEGR  311


>gi|254819983|ref|ZP_05224984.1| methyltransferase [Mycobacterium intracellulare ATCC 13950]
Length=313

 Score =  317 bits (813),  Expect = 1e-84, Method: Compositional matrix adjust.
 Identities = 162/311 (53%), Positives = 209/311 (68%), Gaps = 1/311 (0%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            + RTDND+W I ESVGATALGVA  RAAET S +PLI+DP+A++F++AAGDGIW +Y + 
Sbjct  1    MARTDNDTWDINESVGATALGVAGGRAAETRSADPLISDPYAKLFLEAAGDGIWRVYLDD  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             L A     DP     +Q M+ + A RT FFD+YFLA A  G+RQ+VILA+GLDSRAWRL
Sbjct  61   ELPAELVGADPQFEDRMQAMLGYTACRTKFFDDYFLAAAGEGIRQIVILAAGLDSRAWRL  120

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
             WP G VVYE+DQPKVLEFK  TL+ H   P +  V+V IDLR DWPKAL +AGFD S P
Sbjct  121  AWPAGCVVYEIDQPKVLEFKIGTLKSHAVDPIASHVSVGIDLRLDWPKALAQAGFDASAP  180

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AW AEGL+ YL A AQ LLF+RI +LS PGS +A       F  PE   R+     R R
Sbjct  181  TAWSAEGLLPYLTADAQGLLFDRIQSLSAPGSRVAVEAFTNEFFSPESFARREEQTERYR  240

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPE-LLARYGRSIPHSGED  299
             AA +L   +I++  +L Y E+RT V +WL+  GW V+ AT  E L+A   R++P   + 
Sbjct  241  QAAIRLGGKDITESGNLLYEEERTEVVDWLQAHGWTVTAATSAEDLMAASNRAVPAGLDA  300

Query  300  SIPPNLFVSAQ  310
            ++P ++F+  +
Sbjct  301  AVPESVFIEGR  311


>gi|169630965|ref|YP_001704614.1| hypothetical protein MAB_3886c [Mycobacterium abscessus ATCC 
19977]
 gi|221222918|sp|B1MH79.1|Y3886_MYCA9 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAB_3886c
 gi|169242932|emb|CAM63960.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=314

 Score =  294 bits (752),  Expect = 2e-77, Method: Compositional matrix adjust.
 Identities = 160/311 (52%), Positives = 203/311 (66%), Gaps = 1/311 (0%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYT-NRT  61
            R D DSW ITESVG TALGVA+AR AET S NPLI+DP+A  F+ AAGDG W+ Y  +  
Sbjct  3    RRDGDSWEITESVGTTALGVASARDAETRSPNPLISDPYAGHFLAAAGDGAWNAYRFDGE  62

Query  62   LLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLP  121
              A   + +P L   I  M  ++A RT FFD++F   + +G+RQ VILASGLD+RAWRL 
Sbjct  63   PPAALVEAEPRLVERIDAMRSYVACRTKFFDDFFGDASTSGIRQAVILASGLDARAWRLD  122

Query  122  WPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPC  181
            WP   V++ELD P+VL FK+ TL + GA P  + V V +DLR DWP AL+  GFD  +P 
Sbjct  123  WPRDAVLFELDLPRVLAFKAETLDKQGATPRIRHVPVAVDLRDDWPAALRAGGFDVGRPA  182

Query  182  AWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRA  241
            AW+AEGL+ YLP  AQDLLFERID LS PGS +A    G  F +PE + RQR   +  R 
Sbjct  183  AWIAEGLLPYLPPAAQDLLFERIDTLSAPGSRIAVENFGEDFFNPETLARQRERGQAFRR  242

Query  242  AAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A ++   +I DV DLWY E+RT   E+L  RGW V++ T   LL R+GR IP    D+ 
Sbjct  243  VAEEMQGQDIPDVADLWYLEERTDAGEFLAGRGWRVTSETAVALLGRHGRDIPADLPDAT  302

Query  302  PPNLFVSAQRA  312
            P + F+ AQ+A
Sbjct  303  PNSAFLFAQKA  313


>gi|118467600|ref|YP_884510.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
 gi|221222834|sp|A0QNM2.1|Y095_MYCS2 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MSMEG_0095
 gi|118168887|gb|ABK69783.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
Length=311

 Score =  274 bits (701),  Expect = 1e-71, Method: Compositional matrix adjust.
 Identities = 153/311 (50%), Positives = 192/311 (62%), Gaps = 7/311 (2%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTD+D+W I  SVG+TA+ VAAARA ETE D+ LI DP+A+I V  AG G+W    +   
Sbjct  5    RTDDDTWDIATSVGSTAVMVAAARAGETERDDALIRDPYAKILVAGAGTGVWETVLDSEF  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
             A   +LDP+  A    M ++ A RT FFD Y+   ADAG+RQ+VILASGLDSRA+RL W
Sbjct  65   AAKIENLDPEAAAIFAHMGNYQAVRTHFFDAYYREAADAGIRQIVILASGLDSRAYRLDW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT VYE+DQPKVLE+KSATLR+HG +P +Q   VP+DLR DWP AL  AGFD S P A
Sbjct  125  PAGTTVYEIDQPKVLEYKSATLREHGIEPVAQRREVPVDLRFDWPTALHDAGFDASLPTA  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            WLAEGL+ YLPA AQD LFE +  LS PGS +A    G    D     R+ A   R +  
Sbjct  185  WLAEGLLMYLPAEAQDRLFELVTELSAPGSRIAVETAGVAATD-----RREAMRERFKKF  239

Query  243  AAKLVETEISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGE-DS  300
            A +L  +   D+ +L Y +  R  VAEWL   GW        + + R  R +    + D 
Sbjct  240  ADQLNLSSALDIQELVYDDPDRADVAEWLDAHGWRARGVHALDEMRRLDRLVELPDDPDR  299

Query  301  IPPNLFVSAQR  311
               + FV+AQR
Sbjct  300  AAFSTFVTAQR  310


>gi|296167737|ref|ZP_06849954.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897080|gb|EFG76695.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=312

 Score =  274 bits (701),  Expect = 1e-71, Method: Compositional matrix adjust.
 Identities = 155/310 (50%), Positives = 196/310 (64%), Gaps = 22/310 (7%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +P+ D  S       GATALG+AAARAAET SDNPLI DPFA++FVDAAG GIW++  + 
Sbjct  10   MPQIDGPSSDPAGPAGATALGIAAARAAETASDNPLIQDPFAQVFVDAAGIGIWNVTADP  69

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
              LAG T  DP +R  ++ +I++ A RTAF DE+F+  A  GVRQ+V LA+GLDSRAWRL
Sbjct  70   KRLAGLTATDPGVRPLVRALINYTAVRTAFLDEFFVKAAREGVRQIVNLAAGLDSRAWRL  129

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWPDGT VYELDQP VL+FK ATLR+ GA P SQ+V VP+DLR DWP ALQ+ GFD ++P
Sbjct  130  PWPDGTTVYELDQPAVLDFKYATLRRTGAAPTSQVVGVPVDLRNDWPTALQENGFDAARP  189

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AWLAEGL+ YLPA A  +LFER+ ALS P SW A N PG     P  +           
Sbjct  190  TAWLAEGLLHYLPAWAHGVLFERVHALSPPASWFALNAPGIAGSAPVSVPPGLG------  243

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDS  300
                             W A     +  WL +RGW+    +L  LL  YGR++P    + 
Sbjct  244  ----------TPATTGQWCAAD---IIGWLDQRGWETVALSLETLLNHYGRTVP---GNR  287

Query  301  IPPNLFVSAQ  310
            + P +F++A+
Sbjct  288  VMPTVFITAR  297


>gi|183981610|ref|YP_001849901.1| O-methyltransferase [Mycobacterium marinum M]
 gi|221222861|sp|B2HHB4.1|Y1595_MYCMM RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MMAR_1595
 gi|183174936|gb|ACC40046.1| O-methyltransferase [Mycobacterium marinum M]
Length=318

 Score =  266 bits (680),  Expect = 4e-69, Method: Compositional matrix adjust.
 Identities = 149/277 (54%), Positives = 187/277 (68%), Gaps = 3/277 (1%)

Query  35   PLINDPFARIFVDAAGDGIWSMYTNRTLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEY  94
            PLI DPFA++FVDAAG  +WSM  +          DP L A +Q  +  +A+RT FFDE+
Sbjct  35   PLIVDPFAQLFVDAAGQDLWSMVASGAAHDELASADPALAAVMQTSLGHIASRTKFFDEF  94

Query  95   FLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQ  154
             LA ADAG+RQVV L +GLD+RAWRL WPD   VYEL+QP VLEFK ATLR +GA PA+ 
Sbjct  95   VLAAADAGIRQVVSLGAGLDTRAWRLSWPDAVTVYELEQPNVLEFKLATLRDNGATPAAN  154

Query  155  LVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWL  214
             V+VP+DL + WP++L  AGFDP+ P AWL EGL+ +L   AQDLLF  +  LS PGSWL
Sbjct  155  YVDVPVDLHRCWPRSLCLAGFDPAAPTAWLVEGLLPFLSVAAQDLLFGDVHKLSVPGSWL  214

Query  215  ASNVPGAGFLDPERMRRQRADMRRMRAAAAKLVETEISDVDDLW-YAEQRTAVAEWLRER  273
            A+    + FL P  + RQRA +RRMR  AA L    +S+V +LW  AE R+ VA+WLR R
Sbjct  215  AAEALSSEFLKPTTVARQRARIRRMRVTAATL--AGLSNVTELWDLAEGRSDVADWLRGR  272

Query  274  GWDVSTATLPELLARYGRSIPHSGEDSIPPNLFVSAQ  310
            GW  S  T   LLARY RS P    D+ PP+L+V+A+
Sbjct  273  GWHASVLTAERLLARYHRSAPVELGDATPPSLYVTAR  309


>gi|118464245|ref|YP_883578.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
 gi|221222928|sp|A0QKZ0.1|Y4444_MYCA1 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAV_4444
 gi|118165532|gb|ABK66429.1| methyltransferase, putative, family protein [Mycobacterium avium 
104]
Length=304

 Score =  258 bits (660),  Expect = 6e-67, Method: Compositional matrix adjust.
 Identities = 151/314 (49%), Positives = 187/314 (60%), Gaps = 19/314 (6%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RT +D W +  SVGATA  VAA RA  T+    LI+DPFA   V A G   ++      +
Sbjct  3    RTHDDEWDLASSVGATATMVAAGRAMATKDPRGLIDDPFAEPLVRAVGVDFFT-----KM  57

Query  63   LAGATDLDPDLRAP---IQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWR  119
            + G  DLD    A    IQ M+D MA RT +FD+YF+   DAGVRQVVILASGLDSRA+R
Sbjct  58   MDGELDLDAIENATPVRIQSMVDGMAVRTKYFDDYFVDATDAGVRQVVILASGLDSRAYR  117

Query  120  LPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSK  179
            LPWP GTVVYE+DQP+V+EFKS TL + GA+P +    +PIDLR DWP AL  AGFDP+ 
Sbjct  118  LPWPAGTVVYEIDQPRVIEFKSNTLAEVGAEPTATRRTIPIDLRGDWPAALSAAGFDPAA  177

Query  180  PCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASN-VPGAGFLDPERMRRQRADMRR  238
            P AWLAEGL+ YLP  AQD LF+ I ALS PGS +A+  VPG    D ER+R      R 
Sbjct  178  PTAWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIVDFDAERVREMSGSFRE  237

Query  239  MRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPH-SG  297
                          D+  L YA +R  V ++L   GW     T  EL  R+G  +P    
Sbjct  238  HGVDI---------DMASLVYAGERNHVIDYLNGLGWRAEGVTRTELFHRHGIEVPAPEH  288

Query  298  EDSIPPNLFVSAQR  311
            +D +   +F+SA R
Sbjct  289  DDPLGEIIFISATR  302


>gi|41410287|ref|NP_963123.1| hypothetical protein MAP4189c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|81412956|sp|Q73S87.1|Y4189_MYCPA RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAP_4189c
 gi|41399121|gb|AAS06739.1| hypothetical protein MAP_4189c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336460639|gb|EGO39530.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=304

 Score =  257 bits (657),  Expect = 1e-66, Method: Compositional matrix adjust.
 Identities = 150/314 (48%), Positives = 188/314 (60%), Gaps = 19/314 (6%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RT +D W +  SVGATA  VAA RA  T+    LI+DPFA   V A G   ++      +
Sbjct  3    RTHDDEWDLASSVGATATMVAAGRAMATKDPRGLIDDPFAEPLVRAVGVDFFT-----KM  57

Query  63   LAGATDLDPDLRAP---IQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWR  119
            + G  DLD    A    IQ M+D MA RT +FD+YF+   DAGVR+VVILASGLDSRA+R
Sbjct  58   MDGELDLDAIENATPVRIQSMVDGMAVRTKYFDDYFVDATDAGVRRVVILASGLDSRAYR  117

Query  120  LPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSK  179
            LPWP GTVVYE+DQP+V+EFKS TL + GA+P +    +PIDLR DWP AL  AGFDP+ 
Sbjct  118  LPWPAGTVVYEIDQPRVIEFKSNTLAEVGAEPTATRRTIPIDLRGDWPAALSAAGFDPAA  177

Query  180  PCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASN-VPGAGFLDPERMRRQRADMRR  238
            P AWLAEGL+ YLP  AQD LF+ I ALS PGS +A+  VPG    D ER+R      R+
Sbjct  178  PTAWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIVDFDAERVREMSGSFRQ  237

Query  239  MRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPH-SG  297
                          D+  L YA +R  V ++L   GW     T  EL  R+G  +P    
Sbjct  238  HGVDI---------DMASLVYAGERNHVIDYLNGLGWRAEGVTRTELFHRHGIEVPAPEN  288

Query  298  EDSIPPNLFVSAQR  311
            +D +   +F+SA R
Sbjct  289  DDPLGEIIFISATR  302


>gi|254776879|ref|ZP_05218395.1| methyltransferase, putative, family protein [Mycobacterium avium 
subsp. avium ATCC 25291]
Length=304

 Score =  257 bits (657),  Expect = 2e-66, Method: Compositional matrix adjust.
 Identities = 150/314 (48%), Positives = 186/314 (60%), Gaps = 19/314 (6%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RT +D W +  SVGATA  VAA RA  T+    LI+DPFA   V A G   ++      +
Sbjct  3    RTHDDEWDLASSVGATATMVAAGRAMATKDPRGLIDDPFAEPLVRAVGVDFFT-----KM  57

Query  63   LAGATDLDPDLRAP---IQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWR  119
            + G  DLD    A    IQ M+D MA RT +FD+YF+   DAGVRQVVIL SGLDSRA+R
Sbjct  58   MDGELDLDAIENATPVRIQSMVDGMAVRTKYFDDYFVDATDAGVRQVVILVSGLDSRAYR  117

Query  120  LPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSK  179
            LPWP GTVVYE+DQP+V+EFKS TL + GA+P +    +PIDLR DWP AL  AGFDP+ 
Sbjct  118  LPWPAGTVVYEIDQPRVIEFKSNTLAEVGAEPTATRRTIPIDLRGDWPAALSAAGFDPAA  177

Query  180  PCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASN-VPGAGFLDPERMRRQRADMRR  238
            P AWLAEGL+ YLP  AQD LF+ I ALS PGS +A+  VPG    D ER+R      R 
Sbjct  178  PTAWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIVDFDAERVREMSGSFRE  237

Query  239  MRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPH-SG  297
                          D+  L YA +R  V ++L   GW     T  EL  R+G  +P    
Sbjct  238  HGVDI---------DMASLVYAGERNHVIDYLNGLGWRAEGVTRTELFHRHGIEVPAPEH  288

Query  298  EDSIPPNLFVSAQR  311
            +D +   +F+SA R
Sbjct  289  DDPLGEIIFISATR  302


>gi|145221338|ref|YP_001132016.1| putative methyltransferase [Mycobacterium gilvum PYR-GCK]
 gi|221222945|sp|A4T523.1|Y743_MYCGI RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mflv_0743
 gi|145213824|gb|ABP43228.1| putative methyltransferase [Mycobacterium gilvum PYR-GCK]
Length=309

 Score =  256 bits (655),  Expect = 3e-66, Method: Compositional matrix adjust.
 Identities = 152/310 (50%), Positives = 198/310 (64%), Gaps = 7/310 (2%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTD+D+W I  SVGATA+ VAAARAAETE  + LINDP+A++ V+ AG G W    +  L
Sbjct  5    RTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEGAGAGAWRFIADEDL  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
            +A A++ D ++ A  + M ++ A RT FFD +F A  DAGVRQ+VILASGLDSRA+RLPW
Sbjct  65   VAKASESDTEVGALFEHMKNYQAVRTHFFDAFFSAAVDAGVRQIVILASGLDSRAFRLPW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GTVVYE+DQP VL++KS+TL  HG  P ++   VPIDLRQDWP AL   GFDP++P A
Sbjct  125  PAGTVVYEIDQPLVLDYKSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTA  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            WLAEGL+ YLPA AQD LF +I  LS PGS +A+   G    D    RR+R  MR   A+
Sbjct  185  WLAEGLLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAPD----RRER--MRERFAS  238

Query  243  AAKLVETEISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A  ++ E  D+ +L Y +  R  VAEWL   GW        + + R  R +  +  D  
Sbjct  239  IASQIDIEPMDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRYVEVADSDGQ  298

Query  302  PPNLFVSAQR  311
              + F +  +
Sbjct  299  SFSTFTTGTK  308


>gi|315441778|ref|YP_004074657.1| methyltransferase, , TIGR00027 family [Mycobacterium sp. Spyr1]
 gi|315260081|gb|ADT96822.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
sp. Spyr1]
Length=309

 Score =  255 bits (652),  Expect = 5e-66, Method: Compositional matrix adjust.
 Identities = 151/310 (49%), Positives = 197/310 (64%), Gaps = 7/310 (2%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTD+D+W I  SVGATA+ VAAARAAETE  + LINDP+A++ V+ AG G W    +  L
Sbjct  5    RTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEGAGAGAWRFIADEDL  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
            +A A++ DP++ A  + M ++ A RT FFD +F A  DAGV Q+VILASGLDSRA+RLPW
Sbjct  65   VAKASESDPEVGALFEHMKNYQAVRTHFFDAFFSAAVDAGVSQIVILASGLDSRAFRLPW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GTVVYE+DQP VL++KS+TL  HG  P ++   VPIDLRQDWP  L   GFDP++P A
Sbjct  125  PAGTVVYEIDQPLVLDYKSSTLAAHGVAPTAERREVPIDLRQDWPAELVATGFDPARPTA  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            WLAEGL+ YLPA AQD LF +I  LS PGS +A+   G    D    RR+R  MR   A+
Sbjct  185  WLAEGLLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAPD----RRER--MRERFAS  238

Query  243  AAKLVETEISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSI  301
             A  ++ E  D+ +L Y +  R  VAEWL   GW        + + R  R +  +  D  
Sbjct  239  IASQIDIEPMDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRYVEVADSDGQ  298

Query  302  PPNLFVSAQR  311
              + F +  +
Sbjct  299  SFSTFTTGTK  308


>gi|296167339|ref|ZP_06849741.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897283|gb|EFG76887.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=313

 Score =  254 bits (648),  Expect = 2e-65, Method: Compositional matrix adjust.
 Identities = 142/294 (49%), Positives = 183/294 (63%), Gaps = 9/294 (3%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGI-WSMYTNRT  61
            RT +D+W I  SVG+TA+ VAAARA ETE  +PLI DP+AR+ V+ AG  + W    +  
Sbjct  5    RTHDDTWDIKTSVGSTAVMVAAARAIETEQPDPLIRDPYARLLVNNAGAAVLWEAMLDPE  64

Query  62   LLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLP  121
            ++A    +D +  A IQ M  + A RT FFD YF     AG+RQVVILASGLDSRA+RL 
Sbjct  65   VVAKIEAIDEESAARIQHMRGYQAVRTHFFDSYFADAVGAGIRQVVILASGLDSRAYRLD  124

Query  122  WPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPC  181
            WP GTVVYE+DQP+V+++KSATL   GA P++    V IDLR+DWP AL+ AGFDP+KP 
Sbjct  125  WPAGTVVYEIDQPQVMDYKSATLADSGATPSADRREVAIDLREDWPAALRAAGFDPTKPT  184

Query  182  AWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMR-RMR  240
            AWLAEGL+ YLPA AQD LF +I  LS  GS +++         P     +R  MR R +
Sbjct  185  AWLAEGLLMYLPAEAQDKLFTQIGELSPAGSRVSAETA------PMHAEERRQKMRERFK  238

Query  241  AAAAKLVETEISDVDDLWYA-EQRTAVAEWLRERGWDVSTATLPELLARYGRSI  293
              A +L   E  DV +L Y  E R  + EWL E GW  +     + + R  R +
Sbjct  239  KVADELGLEETVDVGELMYRDEHRADLTEWLNEHGWRATAQNSIDEMHRLNRRV  292


>gi|342859420|ref|ZP_08716074.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
 gi|342133661|gb|EGT86864.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
Length=313

 Score =  253 bits (646),  Expect = 3e-65, Method: Compositional matrix adjust.
 Identities = 145/314 (47%), Positives = 194/314 (62%), Gaps = 11/314 (3%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAG-DGIWSMYTNRT  61
            RT +D+W I  SVG TA+ VAAARA ETE  + LI DP+AR+ V+ AG + +W    +  
Sbjct  5    RTHDDTWDIKSSVGTTAVMVAAARAIETEQPDALIRDPYARLLVNNAGAEVLWEAMLDPE  64

Query  62   LLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLP  121
            ++A    +D +  A +Q M  + A RT FFD YF     AG+RQVVILASGLDSRA+RL 
Sbjct  65   VVAKIEAIDEESAARMQHMRGYQAVRTHFFDSYFADAVAAGIRQVVILASGLDSRAYRLD  124

Query  122  WPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPC  181
            WP GT VYE+DQP+VL++K+ TL + GA+P++    V IDLR+DWP AL+ AGFDP++P 
Sbjct  125  WPAGTTVYEIDQPQVLDYKTTTLAESGAKPSADRREVAIDLREDWPSALRAAGFDPAQPT  184

Query  182  AWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMR-RMR  240
            AWLAEGL+ YLPA AQD LF +I  LS  GS +++         P     +R  MR R +
Sbjct  185  AWLAEGLLMYLPAEAQDKLFTQIGELSPAGSRVSAETA------PMHAEERRQQMRERFK  238

Query  241  AAAAKLVETEISDVDDLWYA-EQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHS--G  297
              AA+L   E  DV +L Y  E R  +A+WL + GW  +     + + R GR +  S   
Sbjct  239  KVAAELGLEETVDVGELMYRDEHRANLADWLNDHGWRATAQNSIDEMHRLGRGVQSSEVD  298

Query  298  EDSIPPNLFVSAQR  311
            ED    + FV A+R
Sbjct  299  EDRDAFSDFVVAKR  312


>gi|145225601|ref|YP_001136279.1| putative methyltransferase [Mycobacterium gilvum PYR-GCK]
 gi|315445954|ref|YP_004078833.1| methyltransferase, , TIGR00027 family [Mycobacterium sp. Spyr1]
 gi|221222972|sp|A4TEC9.1|Y5025_MYCGI RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mflv_5025
 gi|145218087|gb|ABP47491.1| putative methyltransferase [Mycobacterium gilvum PYR-GCK]
 gi|315264257|gb|ADU00999.1| methyltransferase, putative, TIGR00027 family [Mycobacterium 
sp. Spyr1]
Length=307

 Score =  253 bits (645),  Expect = 4e-65, Method: Compositional matrix adjust.
 Identities = 159/315 (51%), Positives = 194/315 (62%), Gaps = 18/315 (5%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAG-DGIWSMYTNRT  61
            RT +DSW +  SVGATA  VAA RA  +   +PLINDP+A   V A G D    M     
Sbjct  3    RTPDDSWDLASSVGATATMVAAGRAVASADPDPLINDPYAEPLVRAVGLDFFTRMLDGEL  62

Query  62   LLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLP  121
             L+   D  P+ RA  Q MID MA RT FFD+  LA A AGVRQVVILA+GLD+R +RLP
Sbjct  63   DLSVFPDSSPE-RA--QAMIDGMAVRTRFFDDCCLAAASAGVRQVVILAAGLDARTYRLP  119

Query  122  WPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPC  181
            WPDGTVVYELDQP V+ FK+ TLR  GA+PA+    VP+DLR+DWP AL+ AGFD ++P 
Sbjct  120  WPDGTVVYELDQPDVIAFKTQTLRNLGAEPAATQRPVPVDLREDWPAALRAAGFDATRPT  179

Query  182  AWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASN-VPGAGFLDPERMRRQRADMRRMR  240
            AWLAEGL+ YLP  AQD LF+ + ALS PGS LA+  VP  G +D         D  + R
Sbjct  180  AWLAEGLLIYLPPEAQDALFDTVTALSAPGSTLATEYVP--GIVD--------FDGAKAR  229

Query  241  AAAAKLVETEIS-DVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPH--SG  297
            A +  L E  +  D+  L Y   RT V + LR  GW VS     EL AR+GR +P    G
Sbjct  230  ALSEPLREHGLDIDMPSLVYTGARTPVMDHLRGAGWQVSGTARAELFARFGRPLPQDADG  289

Query  298  EDSIPPNLFVSAQRA  312
             D +   ++VSA  A
Sbjct  290  TDPLGEIVYVSATLA  304


>gi|333988734|ref|YP_004521348.1| O-methyltransferase [Mycobacterium sp. JDM601]
 gi|333484702|gb|AEF34094.1| O-methyltransferase [Mycobacterium sp. JDM601]
Length=311

 Score =  250 bits (639),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 149/311 (48%), Positives = 189/311 (61%), Gaps = 7/311 (2%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RT +D+W I  SVG+TA+ VAAARA ET+S +PLI+DP+A++ V  AG G+W    N +L
Sbjct  5    RTHDDTWDIATSVGSTAVMVAAARAVETDSSDPLISDPYAKLLVANAGTGVWETLLNESL  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
            +     +DP++ A    M  + A RT FFD YF     AG+RQVVILASGLDSRA+RL W
Sbjct  65   IDKLESVDPEIAAVYHHMRSYQAVRTHFFDAYFAEAVGAGIRQVVILASGLDSRAYRLDW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P  T VYE+DQPKVL +K  TL  H  +   Q   V IDLRQDWP AL  AGFDP+ P A
Sbjct  125  PAATTVYEIDQPKVLGYKETTLAAHDVRAPVQHRAVAIDLRQDWPAALTAAGFDPAAPTA  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAA  242
            WLAEGL+ YLPA AQD LFE+I ALS PGS +A     A   D    RRQ    R  + A
Sbjct  185  WLAEGLLMYLPADAQDRLFEQITALSAPGSRIAVET-AANHAD---QRRQEMSERFKKVA  240

Query  243  AAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGR--SIPHSGEDS  300
                +E  +   D +++ E R AV EWL   GW  +       + R GR  ++P  G+D+
Sbjct  241  EQIGLEQTVDIQDLIYHDEDRAAVPEWLNGHGWRATAQHSTAEMRRLGRWVNVP-MGDDT  299

Query  301  IPPNLFVSAQR  311
               + FV+A R
Sbjct  300  DAFSEFVTAVR  310


>gi|317509168|ref|ZP_07966792.1| O-methyltransferase [Segniliparus rugosus ATCC BAA-974]
 gi|316252525|gb|EFV11971.1| O-methyltransferase [Segniliparus rugosus ATCC BAA-974]
Length=308

 Score =  249 bits (636),  Expect = 4e-64, Method: Compositional matrix adjust.
 Identities = 157/317 (50%), Positives = 187/317 (59%), Gaps = 23/317 (7%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTDNDSW+ITESVGATAL VA  RA E     PL +DPFA  FV AAG+G W        
Sbjct  3    RTDNDSWSITESVGATALMVAVGRALEARQPQPLASDPFAEQFVRAAGEGFW--------  54

Query  63   LAGATDLDPDLRAPIQ-----QMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRA  117
             A A D D DL +  +     ++ D MA RT FFD+ F   A +GVRQ VILA+GLDSRA
Sbjct  55   -AKALDGDIDLTSLPKPRFADRIRDHMAVRTRFFDDLFDQAARSGVRQFVILAAGLDSRA  113

Query  118  WRLPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDP  177
            WRL WPDG+ VYELDQP+VL FK+ TL  H   P +    + +DLR DWP AL  AGFDP
Sbjct  114  WRLDWPDGSAVYELDQPQVLAFKTQTLAGH--TPKADYTPIAVDLRDDWPAALADAGFDP  171

Query  178  SKPCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMR  237
            +KP AWLAEGL+ YLPA AQ+LLFERI  LS PGS +  N    G    ER   Q+A   
Sbjct  172  AKPTAWLAEGLLAYLPAAAQNLLFERIATLSAPGSHVGVNARIGGNYAAERPFWQQA---  228

Query  238  RMRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSG  297
            R   AA  L      D+ DL YAE R   A+WL  RGW    +T   LL    R+     
Sbjct  229  REELAAQGL----DLDMQDLIYAEDRDDPADWLSARGWLTRVSTDEALLKGADRAFETDE  284

Query  298  EDSIPPNLFVSAQRATS  314
            E+  P   ++ A + T+
Sbjct  285  EEHAPRIQYIHATQPTA  301


>gi|169631681|ref|YP_001705330.1| hypothetical protein MAB_4607c [Mycobacterium abscessus ATCC 
19977]
 gi|221222939|sp|B1ML31.1|Y4607_MYCA9 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MAB_4607c
 gi|169243648|emb|CAM64676.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=305

 Score =  249 bits (635),  Expect = 5e-64, Method: Compositional matrix adjust.
 Identities = 151/302 (50%), Positives = 188/302 (63%), Gaps = 18/302 (5%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGI-WSMYTNRT  61
            R D D+W IT SVGATALGVAAARA ET   + LI DPFA+I VDA G    W       
Sbjct  2    RVDGDTWDITSSVGATALGVAAARATETLRADALIRDPFAQILVDATGKATGWER-----  56

Query  62   LLAGATDL-DPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
            L+AG  D  DP+      +M+D+ A RT FFDEYFLA A AG+RQVVILASGLDSRA+RL
Sbjct  57   LVAGDIDWPDPEAGRIYDRMVDYQATRTHFFDEYFLAAAAAGIRQVVILASGLDSRAYRL  116

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
             WP GT VYE+DQP+VL+FK + L  H  QP +Q   V IDLR+DWP AL+ AGFD ++P
Sbjct  117  DWPAGTTVYEIDQPQVLKFKDSALAAH--QPTAQRRGVAIDLREDWPAALRAAGFDSAQP  174

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLA-SNVPGAGFLD---PERMRRQRADM  236
             AWLAEGL+ YLPA AQD LF  I  LS  GS +A     G   LD    E +RR+    
Sbjct  175  TAWLAEGLLPYLPADAQDNLFRDIGVLSAAGSRVAVEGYEGKLVLDESEEEAVRRE----  230

Query  237  RRMRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHS  296
             ++RAA    ++ +++  + ++  E R   AEWL   GW V+     + +AR GR +   
Sbjct  231  -QVRAAFKTAIDVDVTIENLIYEDENRADPAEWLDAHGWSVTKTDAHDEMARLGRPVAED  289

Query  297  GE  298
             E
Sbjct  290  VE  291


>gi|296395198|ref|YP_003660082.1| methyltransferase [Segniliparus rotundus DSM 44985]
 gi|296182345|gb|ADG99251.1| methyltransferase [Segniliparus rotundus DSM 44985]
Length=616

 Score =  248 bits (634),  Expect = 6e-64, Method: Compositional matrix adjust.
 Identities = 149/313 (48%), Positives = 197/313 (63%), Gaps = 15/313 (4%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PR DND+W+I ESVG TA+ VAAARA ET   + LINDP A   V A+G   +      
Sbjct  317  MPRNDNDTWSIAESVGVTAVMVAAARAHETAKPDGLINDPHAATLVRASGVPFFVRS---  373

Query  61   TLLAGATDL--DPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAW  118
              L G  +L  DP + A ++ ++ + AART  FD +F   A+AGVRQ VILASGLDSRA+
Sbjct  374  --LDGEVELGDDPLISAYVEALVSYQAARTTVFDRFFQEAAEAGVRQAVILASGLDSRAY  431

Query  119  RLPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPS  178
            RLPWPDGT VYE+DQP+VL FK+ TL      P ++ V VP+DLR+DWPK+L +AG DP+
Sbjct  432  RLPWPDGTTVYEIDQPQVLAFKAETLAD--VVPTARRVAVPVDLREDWPKSLAEAGLDPA  489

Query  179  KPCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRR  238
            +P AWLAEGL+ YLPA A+ LLFERID+L+ PGS +A     A  +  ER + Q    RR
Sbjct  490  EPVAWLAEGLLPYLPAEAERLLFERIDSLAAPGSRIAVENWPARAVTAERQQLQ----RR  545

Query  239  MRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGE  298
            + +  A  ++ +I D+  ++  E R  V  WL E G+ V      E+LA  GR+      
Sbjct  546  VFSTVAPDLDLDIEDL--VFQGEDRLDVPGWLAEHGFAVQNTPSQEVLAALGRTPDPRVA  603

Query  299  DSIPPNLFVSAQR  311
            D+ P + FV A R
Sbjct  604  DARPQSYFVIANR  616


 Score =  186 bits (473),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 132/293 (46%), Positives = 169/293 (58%), Gaps = 13/293 (4%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTD+D+W+ITESVGATAL VA ARA E    +PL  DPFA + V AAG G W+       
Sbjct  3    RTDDDTWSITESVGATALLVATARAFEARKADPLATDPFAELLVSAAG-GKWA-----AA  56

Query  63   LAGATDLDPDLRAPIQQMI--DFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
            L G   +          M    +  ART FFD  F A   AGVRQ VILA+GLD+RA+RL
Sbjct  57   LRGEGPVFEAFGTSWFGMSFQRYQGARTQFFDAVFAAAEAAGVRQYVILAAGLDARAYRL  116

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
             +P+G+ V+ELDQP VL+FK+ TL   G  PA+  V VPIDLRQDWP AL KAGF P+KP
Sbjct  117  SYPEGSRVFELDQPHVLDFKTQTLAGIGVAPAAGRVTVPIDLRQDWPTALVKAGFAPAKP  176

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             AWL EGL+ YL A+A+ LL ER+ +LS PGSW      G   + P      + ++RR+ 
Sbjct  177  SAWLVEGLLMYLSAKAETLLLERLLSLSAPGSWA-----GIEHMQPMDAEGMQQEVRRLA  231

Query  241  AAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSI  293
                       S+  +L Y E R  + E L   GW     +  + +A+ G  +
Sbjct  232  PQITDGAANWSSNFAELIYNEPRPDLVERLTAEGWAAQGVSSAKHMAQLGHPV  284


>gi|317509171|ref|ZP_07966795.1| O-methyltransferase [Segniliparus rugosus ATCC BAA-974]
 gi|316252528|gb|EFV11974.1| O-methyltransferase [Segniliparus rugosus ATCC BAA-974]
Length=302

 Score =  248 bits (633),  Expect = 8e-64, Method: Compositional matrix adjust.
 Identities = 144/296 (49%), Positives = 189/296 (64%), Gaps = 13/296 (4%)

Query  1    VPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNR  60
            +PRTD+D+W+I ESVGATA+ VAAARA  T+++N +I+D FA   V+A G   WS +   
Sbjct  1    MPRTDDDTWSIAESVGATAVMVAAARAIATKAENAIISDQFAEPLVNAVGVEFWSKFAAG  60

Query  61   TLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRL  120
             +     D +    +P   M + MA RT FFDE+F +   +GVRQ VILASGLDSRA+RL
Sbjct  61   EIAISEED-ERQFGSPTV-MANSMAVRTRFFDEFFASAGQSGVRQAVILASGLDSRAYRL  118

Query  121  PWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKP  180
            PWP+GT V+ELDQP+V+EFK+ TL   GA+P ++ V +P+DLR DWPKAL +AGFDP  P
Sbjct  119  PWPEGTTVFELDQPQVIEFKTDTLAALGAEPTAKRVAIPVDLRHDWPKALVEAGFDPKSP  178

Query  181  CAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMR  240
             +W  EGL  YLPA A+ LL+ERID LS PGSW+A           E +     D  R +
Sbjct  179  SSWSVEGLTPYLPAEAELLLYERIDELSAPGSWVAVEY-------IEHLHELPTD--RFQ  229

Query  241  AAAAKLVETEIS-DVDDLWYA-EQRTAVAEWLRERGWDVSTATLPELLARYGRSIP  294
            AAA +  E  +  D+ +L+Y  E+R    EW  ERGW   T T  +LLA+    IP
Sbjct  230  AAAKRFAELGLDLDMSNLFYRDEERGDTTEWFAERGWATETVTSSQLLAQADLPIP  285


>gi|118473880|ref|YP_885025.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
 gi|221222940|sp|A0QQ37.1|Y614_MYCS2 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MSMEG_0614
 gi|118175167|gb|ABK76063.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
Length=297

 Score =  247 bits (631),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 146/297 (50%), Positives = 178/297 (60%), Gaps = 27/297 (9%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RTDND W IT SVG TAL VAA+RA E    +PL  D +A +F  AAG G W        
Sbjct  2    RTDNDQWDITISVGQTALFVAASRALEARKPHPLAVDHYAEVFCRAAG-GDW--------  52

Query  63   LAGATDLDPDLRAPIQQ-----MIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRA  117
            +A     DP+   P+Q       ++F  ART +FD+YF   ADAGVRQVV+LA+GLDSRA
Sbjct  53   VAAVEGTDPE--HPLQTEFGVDFVNFQGARTKYFDDYFRRVADAGVRQVVLLAAGLDSRA  110

Query  118  WRLPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDP  177
            +RLPW DGTVVYELD PKVLEFK   LR+HGA P ++   VP+DLR DWP AL+  GFD 
Sbjct  111  YRLPWADGTVVYELDVPKVLEFKREVLRRHGATPTAERREVPVDLRDDWPAALRANGFDA  170

Query  178  SKPCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMR  237
            S+P AW+AEGL+ YLPA AQ+LLF  IDALS PGS++A        +D   ++R  A   
Sbjct  171  SQPSAWIAEGLLIYLPADAQELLFAGIDALSAPGSFVAIEESAPMPMDVFEVKRAEA---  227

Query  238  RMRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIP  294
                    L   + +    L + EQ     +W  ERGW  ST TL E L   GR  P
Sbjct  228  --------LASGDPNSFFALVFNEQCAPGEQWFSERGWTASTTTLNECLHEVGRPAP  276


>gi|254822359|ref|ZP_05227360.1| methyltransferase, putative, family protein [Mycobacterium intracellulare 
ATCC 13950]
Length=313

 Score =  246 bits (628),  Expect = 3e-63, Method: Compositional matrix adjust.
 Identities = 137/294 (47%), Positives = 181/294 (62%), Gaps = 9/294 (3%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAG-DGIWSMYTNRT  61
            RT +D+W I  SVG TA+ VAAARA ETE  + LI DP+AR+ V+ AG D +W    +  
Sbjct  5    RTHDDTWDIKSSVGTTAVMVAAARAIETEQPDALIRDPYARLLVNNAGADVLWEAMLDPD  64

Query  62   LLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLP  121
            ++A    +D +  A IQ M  + A RT FFDEYF      G+RQVVILASGLDSRA+RL 
Sbjct  65   VVAKIEAIDEESAARIQHMRGYQAVRTHFFDEYFADAVATGIRQVVILASGLDSRAYRLD  124

Query  122  WPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPC  181
            WP GT VYE+DQP+VL++K+ TL + G  P++    V IDLR+DWP AL+ AGFDP++P 
Sbjct  125  WPAGTTVYEIDQPQVLDYKTTTLAESGVTPSADRREVAIDLREDWPAALRAAGFDPTRPT  184

Query  182  AWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMR-RMR  240
            AWLAEGL+ YLPA AQD LF +I  LS  GS +++         P     +R  MR R +
Sbjct  185  AWLAEGLLMYLPAEAQDKLFTQIGELSPAGSRVSAETA------PMHAEERRQQMRERFK  238

Query  241  AAAAKLVETEISDVDDLWYA-EQRTAVAEWLRERGWDVSTATLPELLARYGRSI  293
              A +L   E  DV +L Y  E R  +A+WL + GW  +     + + R  R +
Sbjct  239  KVADQLGLEETIDVGELMYRDEHRANLADWLNDHGWRATAQNSIDEMHRLNRGV  292


>gi|108797069|ref|YP_637266.1| hypothetical protein Mmcs_0088 [Mycobacterium sp. MCS]
 gi|119866154|ref|YP_936106.1| putative methyltransferase [Mycobacterium sp. KMS]
 gi|123179785|sp|Q1BFX4.1|Y088_MYCSS RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mmcs_0088
 gi|221222835|sp|A1U908.1|Y097_MYCSK RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
Mkms_0097
 gi|108767488|gb|ABG06210.1| Protein of unknown function Mtu_121 [Mycobacterium sp. MCS]
 gi|119692243|gb|ABL89316.1| putative methyltransferase [Mycobacterium sp. KMS]
Length=312

 Score =  246 bits (628),  Expect = 3e-63, Method: Compositional matrix adjust.
 Identities = 154/312 (50%), Positives = 196/312 (63%), Gaps = 9/312 (2%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RT +D+W I  SVG+TA+ VAA+RAAETE D  LI DP+AR+ V  AG GIW    +   
Sbjct  5    RTADDTWDIATSVGSTAVMVAASRAAETERDEALIRDPYARLLVTGAGTGIWESVLDAKF  64

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
            +      D +  A  + MI + A RT FFD +F A A+AG+RQ+VILASGLDSRA+RL W
Sbjct  65   VETVAAADAEAAAIFEHMISYQAVRTHFFDAFFTAAAEAGIRQIVILASGLDSRAYRLDW  124

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GT VYE+DQPKVLE+KSATL +HG +PA+    V IDLR DWP AL+ AGFDPS+P A
Sbjct  125  PSGTTVYEIDQPKVLEYKSATLAEHGVEPAATRREVGIDLRHDWPAALRGAGFDPSRPTA  184

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMR-RMRA  241
            WLAEGL+ YLPA AQD LFE+I  LS PGS +A+   G    D    RRQ+  MR R   
Sbjct  185  WLAEGLLMYLPADAQDRLFEQITELSAPGSRVAAETAGVQAED----RRQQ--MRERFER  238

Query  242  AAAKLVETEISDVDDLWYAE-QRTAVAEWLRERGWDVSTATLPELLARYGR-SIPHSGED  299
             A K   T   D+  L Y +  R  VA+WL   GW  +  +  + + R  R ++P    D
Sbjct  239  IAEKFDMTASLDIQQLIYEDPDRADVADWLDAHGWTATAVSSQQEMRRLDRWALPADLTD  298

Query  300  SIPPNLFVSAQR  311
                + FV+A++
Sbjct  299  DDAFSNFVTAEK  310


>gi|296168585|ref|ZP_06850389.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295896648|gb|EFG76287.1| methyltransferase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=307

 Score =  246 bits (628),  Expect = 3e-63, Method: Compositional matrix adjust.
 Identities = 144/316 (46%), Positives = 186/316 (59%), Gaps = 22/316 (6%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            R  +D W +  SVGATA  VAA RA  T+    LI+DPFA   V A G   ++      +
Sbjct  3    RAHDDEWDLASSVGATATMVAAGRAMATKDPRGLIHDPFAEPLVRAVGVDFFT-----KM  57

Query  63   LAGATDLDPDLRAP---IQQMIDFMAARTAFFDEYF---LATADAGVRQVVILASGLDSR  116
            + G  DLD    A    +Q M+D MA RT +FD+YF   +     G+RQ VILASGLDSR
Sbjct  58   MDGDLDLDAIENASQVRMQAMVDGMAVRTKYFDDYFAQNMGATGGGIRQAVILASGLDSR  117

Query  117  AWRLPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFD  176
            A+RLPWPDGTVVYE+DQP+V+EFK++TL   GA+P +    VPIDLR DWP AL+ AGFD
Sbjct  118  AYRLPWPDGTVVYEIDQPRVIEFKTSTLTGIGAEPTATRRTVPIDLRADWPAALRAAGFD  177

Query  177  PSKPCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASN-VPGAGFLDPERMRRQRAD  235
            P+ P AWLAEGL+ YLP  AQD LF+ I ALS PGS +A+  VPG    D +++R     
Sbjct  178  PAAPTAWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIVDFDADKVREMSGS  237

Query  236  MRRMRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSI-P  294
             R               D+  L YA +R  V ++LR + WDV   T  EL  R G  + P
Sbjct  238  FREHGVDI---------DMASLVYAGERNHVLDYLRSKKWDVDGTTRTELFRRQGIEVPP  288

Query  295  HSGEDSIPPNLFVSAQ  310
               +D +   +F+S +
Sbjct  289  PQNDDPLGEIIFISGR  304


>gi|342861820|ref|ZP_08718465.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
 gi|342130637|gb|EGT83941.1| methyltransferase, putative, family protein [Mycobacterium colombiense 
CECT 3035]
Length=306

 Score =  246 bits (627),  Expect = 4e-63, Method: Compositional matrix adjust.
 Identities = 146/314 (47%), Positives = 182/314 (58%), Gaps = 13/314 (4%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            RT +D W +  SVGATA  VAA RA  T+    LINDPFA   V A G   ++   +  L
Sbjct  3    RTHDDEWDLASSVGATATMVAAGRAMATKDPRGLINDPFAEPLVRAVGVDFFTKMMDGDL  62

Query  63   LAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPW  122
               A +    +R  IQ M+D MA RT +FD+YF+ +   GVRQVVILASGLDSRA+RLPW
Sbjct  63   DVDAIENASPVR--IQSMVDGMAVRTKYFDDYFIDSTGGGVRQVVILASGLDSRAFRLPW  120

Query  123  PDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCA  182
            P GTVVYE+DQP+V+EFKS TL   GA+P +    +PIDLR DWP AL+ AGFD +   A
Sbjct  121  PAGTVVYEIDQPRVIEFKSNTLADVGAEPTASRRTIPIDLRADWPAALKAAGFDTTAATA  180

Query  183  WLAEGLVRYLPARAQDLLFERIDALSRPGSWLASN-VPGAGFLDPERMRRQRADMRRMRA  241
            WLAEGL+ YLP  AQD LF+ I ALS PGS +A+  VPG    D ER+R      R    
Sbjct  181  WLAEGLLIYLPPDAQDRLFDNITALSGPGSTIATEFVPGIVDFDAERVREMSGSFREHGV  240

Query  242  AAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPH-SGEDS  300
                       D+  L YA +R  V ++L   GW     T  EL  R G   P    +D 
Sbjct  241  DI---------DMASLVYAGERNHVVDYLSSIGWRAEGITRTELFERNGIEAPAPENDDP  291

Query  301  IPPNLFVSAQRATS  314
            +   +F+SA+   S
Sbjct  292  LGEIIFISAKLTGS  305


>gi|118470302|ref|YP_885861.1| methyltransferase, , family protein [Mycobacterium smegmatis 
str. MC2 155]
 gi|221222856|sp|A0QSH3.1|Y1479_MYCS2 RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase 
MSMEG_1479
 gi|118171589|gb|ABK72485.1| methyltransferase, putative, family protein [Mycobacterium smegmatis 
str. MC2 155]
Length=303

 Score =  245 bits (626),  Expect = 5e-63, Method: Compositional matrix adjust.
 Identities = 142/312 (46%), Positives = 184/312 (59%), Gaps = 19/312 (6%)

Query  3    RTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTL  62
            R+DND+W +  SVGATA  VAA RA  ++    LINDPFA   V A G    +M  +   
Sbjct  3    RSDNDTWDLASSVGATATMVAAGRAVVSQDPGGLINDPFAAPLVRAVGIEALTMLAD---  59

Query  63   LAGATDLD---PDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWR  119
              G  D++   P+  A ++  ID MA RT FFD+YF+     GV Q VILASGLDSRA+R
Sbjct  60   --GKFDIEKVLPESAARVRANIDEMAVRTKFFDDYFMDATGRGVGQAVILASGLDSRAYR  117

Query  120  LPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSK  179
            LPWPDGTVVYE+DQP V+EFK+ TL   GA+P  +   V IDLR DWP AL+ AGFDPS 
Sbjct  118  LPWPDGTVVYEIDQPDVIEFKTRTLADLGAEPTCERRTVSIDLRDDWPAALRAAGFDPSA  177

Query  180  PCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASN-VPGAGFLDPERMRRQRADMRR  238
            P AW AEGL+ YLP  AQD LF+ I  LS PGS +A+  VP     DPE+ R+    + R
Sbjct  178  PTAWCAEGLLIYLPPEAQDKLFDDIHHLSAPGSTVATEFVPALKDFDPEKARQATETLTR  237

Query  239  MRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIP-HSG  297
            M             D+  L Y  +R + +++L  +GW + +A    L  RYG   P H  
Sbjct  238  MGVDI---------DMPSLIYHGERHSASDYLETKGWQMDSAARATLFTRYGLPAPGHDD  288

Query  298  EDSIPPNLFVSA  309
            +D +   +++S 
Sbjct  289  DDPLGEIIYISG  300



Lambda     K      H
   0.319    0.133    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 543016982550


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40