BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3830c Length=209 Score E Sequences producing significant alignments: (Bits) Value gi|15610966|ref|NP_218347.1| transcriptional regulatory protein ... 418 2e-115 gi|289747671|ref|ZP_06507049.1| dehydrogenase [Mycobacterium tub... 418 3e-115 gi|294993041|ref|ZP_06798732.1| dehydrogenase [Mycobacterium tub... 417 5e-115 gi|298527305|ref|ZP_07014714.1| LOW QUALITY PROTEIN: transcripti... 415 2e-114 gi|289759997|ref|ZP_06519375.1| LOW QUALITY PROTEIN: transcripti... 415 2e-114 gi|183985352|ref|YP_001853643.1| TetR family transcriptional reg... 328 3e-88 gi|41406299|ref|NP_959135.1| hypothetical protein MAP0201 [Mycob... 327 6e-88 gi|254822669|ref|ZP_05227670.1| transcriptional regulator, TetR ... 325 2e-87 gi|342860083|ref|ZP_08716735.1| TetR family transcriptional regu... 324 6e-87 gi|118620019|ref|YP_908351.1| TetR family transcriptional regula... 323 1e-86 gi|240172630|ref|ZP_04751289.1| transcriptional regulator, TetR ... 319 1e-85 gi|296166958|ref|ZP_06849374.1| TetR family transcriptional regu... 318 3e-85 gi|333992777|ref|YP_004525391.1| TetR family transcriptional reg... 276 2e-72 gi|108801469|ref|YP_641666.1| TetR family transcriptional regula... 270 8e-71 gi|315442699|ref|YP_004075578.1| TetR family transcriptional reg... 268 6e-70 gi|145222268|ref|YP_001132946.1| TetR family transcriptional reg... 267 7e-70 gi|120406025|ref|YP_955854.1| TetR family transcriptional regula... 267 9e-70 gi|120402004|ref|YP_951833.1| TetR family transcriptional regula... 117 1e-24 gi|118618342|ref|YP_906674.1| TetR family transcriptional regula... 114 9e-24 gi|183982816|ref|YP_001851107.1| TetR family transcriptional reg... 113 2e-23 gi|296164937|ref|ZP_06847493.1| TetR family transcriptional regu... 113 2e-23 gi|118463380|ref|YP_881976.1| TetR family transcriptional regula... 105 5e-21 gi|254821868|ref|ZP_05226869.1| transcriptional regulator, TetR ... 96.3 3e-18 gi|342859565|ref|ZP_08716218.1| TetR family transcriptional regu... 87.8 8e-16 gi|302545755|ref|ZP_07298097.1| HTH-type transcriptional regulat... 79.0 5e-13 gi|345014806|ref|YP_004817160.1| regulatory protein TetR [Strept... 72.4 4e-11 gi|730916|sp|P39885.1|TCMR_STRGA RecName: Full=HTH-type transcri... 70.9 1e-10 gi|153489|gb|AAA67508.1| tetracenomycin C resistance and export ... 70.9 1e-10 gi|229490652|ref|ZP_04384490.1| transcriptional regulator, AcrR ... 69.7 2e-10 gi|328882236|emb|CCA55475.1| Transcriptional regulator, TetR fam... 69.3 3e-10 gi|226305285|ref|YP_002765243.1| TetR family transcriptional reg... 69.3 3e-10 gi|291455176|ref|ZP_06594566.1| TetR-family transcriptional regu... 68.9 5e-10 gi|302534244|ref|ZP_07286586.1| TetR family transcriptional regu... 67.8 1e-09 gi|291436189|ref|ZP_06575579.1| transcriptional regulator [Strep... 67.4 1e-09 gi|302557327|ref|ZP_07309669.1| TetR-family transcriptional regu... 67.4 1e-09 gi|297194570|ref|ZP_06911968.1| TetR-family transcriptional regu... 67.0 1e-09 gi|294629135|ref|ZP_06707695.1| HTH-type transcriptional regulat... 67.0 2e-09 gi|302541632|ref|ZP_07293974.1| putative transcriptional regulat... 67.0 2e-09 gi|337768835|emb|CCB77548.1| conserved protein of unknown functi... 67.0 2e-09 gi|21224778|ref|NP_630557.1| transcriptional regulator [Streptom... 66.6 2e-09 gi|337765495|emb|CCB74204.1| HTH-type transcriptional regulator ... 66.2 2e-09 gi|254382183|ref|ZP_04997544.1| conserved hypothetical protein [... 66.2 2e-09 gi|302537843|ref|ZP_07290185.1| TetR family transcriptional regu... 66.2 3e-09 gi|302518798|ref|ZP_07271140.1| TetR-family transcriptional regu... 66.2 3e-09 gi|226365537|ref|YP_002783320.1| TetR family transcriptional reg... 66.2 3e-09 gi|329940347|ref|ZP_08289628.1| transcriptional regulator [Strep... 66.2 3e-09 gi|302555237|ref|ZP_07307579.1| TetR-family transcriptional regu... 66.2 3e-09 gi|345010150|ref|YP_004812504.1| regulatory protein TetR [Strept... 65.9 3e-09 gi|254390172|ref|ZP_05005392.1| HTH-type transcriptional regulat... 65.9 4e-09 gi|29828452|ref|NP_823086.1| TetR family transcriptional regulat... 65.9 4e-09 >gi|15610966|ref|NP_218347.1| transcriptional regulatory protein TetR-family [Mycobacterium tuberculosis H37Rv] gi|15843454|ref|NP_338491.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31795004|ref|NP_857497.1| transcriptional regulatory protein TetR-family [Mycobacterium bovis AF2122/97] 70 more sequence titles Length=209 Score = 418 bits (1075), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 209/209 (100%), Positives = 209/209 (100%), Gaps = 0/209 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL Sbjct 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR Sbjct 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL Sbjct 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 Query 181 GELARVCHVALESLRVGISDTWTTLTVSS 209 GELARVCHVALESLRVGISDTWTTLTVSS Sbjct 181 GELARVCHVALESLRVGISDTWTTLTVSS 209 >gi|289747671|ref|ZP_06507049.1| dehydrogenase [Mycobacterium tuberculosis 02_1987] gi|289688199|gb|EFD55687.1| dehydrogenase [Mycobacterium tuberculosis 02_1987] Length=762 Score = 418 bits (1074), Expect = 3e-115, Method: Compositional matrix adjust. Identities = 207/207 (100%), Positives = 207/207 (100%), Gaps = 0/207 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL Sbjct 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR Sbjct 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL Sbjct 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 Query 181 GELARVCHVALESLRVGISDTWTTLTV 207 GELARVCHVALESLRVGISDTWTTLTV Sbjct 181 GELARVCHVALESLRVGISDTWTTLTV 207 >gi|294993041|ref|ZP_06798732.1| dehydrogenase [Mycobacterium tuberculosis 210] gi|339296638|gb|AEJ48749.1| dehydrogenase [Mycobacterium tuberculosis CCDC5079] gi|339300235|gb|AEJ52345.1| dehydrogenase [Mycobacterium tuberculosis CCDC5180] Length=741 Score = 417 bits (1072), Expect = 5e-115, Method: Compositional matrix adjust. Identities = 207/207 (100%), Positives = 207/207 (100%), Gaps = 0/207 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL Sbjct 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR Sbjct 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL Sbjct 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 Query 181 GELARVCHVALESLRVGISDTWTTLTV 207 GELARVCHVALESLRVGISDTWTTLTV Sbjct 181 GELARVCHVALESLRVGISDTWTTLTV 207 >gi|298527305|ref|ZP_07014714.1| LOW QUALITY PROTEIN: transcriptional regulatory protein [Mycobacterium tuberculosis 94_M4241A] gi|298497099|gb|EFI32393.1| LOW QUALITY PROTEIN: transcriptional regulatory protein [Mycobacterium tuberculosis 94_M4241A] Length=207 Score = 415 bits (1067), Expect = 2e-114, Method: Compositional matrix adjust. Identities = 207/207 (100%), Positives = 207/207 (100%), Gaps = 0/207 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL Sbjct 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR Sbjct 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL Sbjct 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 Query 181 GELARVCHVALESLRVGISDTWTTLTV 207 GELARVCHVALESLRVGISDTWTTLTV Sbjct 181 GELARVCHVALESLRVGISDTWTTLTV 207 >gi|289759997|ref|ZP_06519375.1| LOW QUALITY PROTEIN: transcriptional regulatory protein TetR-family [Mycobacterium tuberculosis T85] gi|289715561|gb|EFD79573.1| LOW QUALITY PROTEIN: transcriptional regulatory protein TetR-family [Mycobacterium tuberculosis T85] gi|326905667|gb|EGE52600.1| LOW QUALITY PROTEIN: transcriptional regulator, tetR-family [Mycobacterium tuberculosis W-148] Length=210 Score = 415 bits (1067), Expect = 2e-114, Method: Compositional matrix adjust. Identities = 207/207 (100%), Positives = 207/207 (100%), Gaps = 0/207 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL Sbjct 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR Sbjct 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL Sbjct 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 Query 181 GELARVCHVALESLRVGISDTWTTLTV 207 GELARVCHVALESLRVGISDTWTTLTV Sbjct 181 GELARVCHVALESLRVGISDTWTTLTV 207 >gi|183985352|ref|YP_001853643.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|183178678|gb|ACC43788.1| transcriptional regulatory protein (probably TetR-family) [Mycobacterium marinum M] Length=215 Score = 328 bits (841), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 163/206 (80%), Positives = 181/206 (88%), Gaps = 5/206 (2%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QT RSERTREALRQAA+VRFLAQGVE TSAEQIA DAGVSLRTFYRHFRSKHDLL Sbjct 1 MVRPAQTVRSERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRTFYRHFRSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADY GLHWFRAALDARP DE+IIDSVQ AIF+FPYDV+AV KIA+LR GEL+PSRIVR Sbjct 61 FADY-TGLHWFRAALDARPVDETIIDSVQTAIFAFPYDVEAVAKIATLRGGELDPSRIVR 119 Query 121 HMREVEADFADAIQAQLRRRNCDIAG----APDARLHIAVTARCVAAAVFGAMEAWMLGS 176 H++EV+ADFA+ I AQLRRR+C AG PDAR+ AVTARC+AAAVFGAME WMLG Sbjct 120 HIQEVQADFAEVIAAQLRRRSCAAAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGE 179 Query 177 DRSLGELARVCHVALESLRVGISDTW 202 DRSLGELARVC +ALE+LR G+++TW Sbjct 180 DRSLGELARVCQLALETLRAGLTNTW 205 >gi|41406299|ref|NP_959135.1| hypothetical protein MAP0201 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118463146|ref|YP_879491.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|254773256|ref|ZP_05214772.1| transcriptional regulator, TetR family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|41394647|gb|AAS02518.1| hypothetical protein MAP_0201 [Mycobacterium avium subsp. paratuberculosis K-10] gi|118164433|gb|ABK65330.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] gi|336461887|gb|EGO40742.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=212 Score = 327 bits (838), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 169/208 (82%), Positives = 184/208 (89%), Gaps = 4/208 (1%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QTARSERTREALRQAALVRFLAQGVE TSAEQIA DAGVSLRTFYRHFRSKHDLL Sbjct 1 MVRPAQTARSERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFRSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADY GLHWFRAALDARPADE IIDSVQAAIFSFPYDVDAVTKIA+LR EL+P RIVR Sbjct 61 FADY-TGLHWFRAALDARPADEPIIDSVQAAIFSFPYDVDAVTKIAALRHEELDPGRIVR 119 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAP--DARLHIAVTARCVAAAVFGAMEAWMLGSDR 178 H+R+V+ADFA+AI AQL+RR AGAP D R+ AVTARC+AAAVFGAME WM+G +R Sbjct 120 HIRDVQADFAEAIAAQLQRRGRG-AGAPTADQRVRAAVTARCIAAAVFGAMEVWMVGDER 178 Query 179 SLGELARVCHVALESLRVGISDTWTTLT 206 SLGELAR+CH ALESLR GI+D+W+T T Sbjct 179 SLGELARLCHAALESLRAGITDSWSTAT 206 >gi|254822669|ref|ZP_05227670.1| transcriptional regulator, TetR family protein [Mycobacterium intracellulare ATCC 13950] Length=212 Score = 325 bits (834), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 166/207 (81%), Positives = 180/207 (87%), Gaps = 2/207 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QTARSERTREALRQAALVRFLAQGVE TSAEQIA DAGVSLRTFYRHF SKHDLL Sbjct 1 MVRPAQTARSERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFSSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADY GLHWFRAALDARPADE IIDSVQ+AIFSFPYDVDAVTKIA+LR+ EL+P RIVR Sbjct 61 FADY-TGLHWFRAALDARPADEPIIDSVQSAIFSFPYDVDAVTKIAALRQDELDPGRIVR 119 Query 121 HMREVEADFADAIQAQLRRRN-CDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRS 179 H+REV+ADFADAI AQLRRR + D R+ AVTARC+AAAVFGAME WM+G +RS Sbjct 120 HIREVQADFADAIAAQLRRRGRGNAEPTADQRVRTAVTARCIAAAVFGAMEVWMVGDERS 179 Query 180 LGELARVCHVALESLRVGISDTWTTLT 206 LGELAR+CH ALESLR GI+D+W T T Sbjct 180 LGELARLCHAALESLRAGITDSWLTAT 206 >gi|342860083|ref|ZP_08716735.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342132461|gb|EGT85690.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=215 Score = 324 bits (830), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 166/210 (80%), Positives = 181/210 (87%), Gaps = 5/210 (2%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QTARSERTREALRQAALVRFLAQGVE TSAEQIA DAGVSLRTFYRHF SKHDLL Sbjct 1 MVRPAQTARSERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFSSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADY GLHWFR+ALDARPADE IIDSVQAA+FSFPYDVDAVTKIA+LR+ EL+P RIVR Sbjct 61 FADY-TGLHWFRSALDARPADEPIIDSVQAAVFSFPYDVDAVTKIAALRQDELDPGRIVR 119 Query 121 HMREVEADFADAIQAQLRRRNCDIAGA----PDARLHIAVTARCVAAAVFGAMEAWMLGS 176 H+REV+ADFADAI AQL+RR+ GA D R+ IAVTARC+AAAVFGAME WM Sbjct 120 HIREVQADFADAIGAQLQRRSRGTNGAANPSADRRVRIAVTARCIAAAVFGAMEVWMESD 179 Query 177 DRSLGELARVCHVALESLRVGISDTWTTLT 206 +RSLGELAR+CH ALESLR GI+D+W T T Sbjct 180 ERSLGELARLCHAALESLRAGITDSWVTAT 209 >gi|118620019|ref|YP_908351.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|118572129|gb|ABL06880.1| transcriptional regulatory protein (probably TetR-family) [Mycobacterium ulcerans Agy99] Length=215 Score = 323 bits (827), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 161/206 (79%), Positives = 179/206 (87%), Gaps = 5/206 (2%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QT RSERTREALRQAA+VRFLAQGVE TSAEQIA DAGVSLRTFYRHFRSKHDLL Sbjct 1 MVRPAQTVRSERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRTFYRHFRSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADY GLHWFRAALDARP DE+IIDSVQ AIF+FPYDV+AV KIA+LR GEL+PSRIVR Sbjct 61 FADY-TGLHWFRAALDARPVDEAIIDSVQTAIFAFPYDVEAVAKIATLRGGELDPSRIVR 119 Query 121 HMREVEADFADAIQAQLRRRNCDIAG----APDARLHIAVTARCVAAAVFGAMEAWMLGS 176 H++EV+ADFA+ I AQL RR+C AG PDAR+ AVTARC+AAAVFGAME WMLG Sbjct 120 HIQEVQADFAEVIAAQLLRRSCAAAGTSAQTPDARVRTAVTARCIAAAVFGAMEVWMLGE 179 Query 177 DRSLGELARVCHVALESLRVGISDTW 202 DRSLGELARVC +ALE+ R G+++TW Sbjct 180 DRSLGELARVCQLALETSRAGLTNTW 205 >gi|240172630|ref|ZP_04751289.1| transcriptional regulator, TetR family protein [Mycobacterium kansasii ATCC 12478] Length=208 Score = 319 bits (818), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 160/209 (77%), Positives = 179/209 (86%), Gaps = 1/209 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QTARSERTREALRQAALVRFLAQGV TSAEQIA DAGVSLRTFYRHF SKHDLL Sbjct 1 MVRPAQTARSERTREALRQAALVRFLAQGVADTSAEQIAADAGVSLRTFYRHFHSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADY GLHWFR ALDARPADE IIDSV+AA+F+FPYDV+AVTKIA+LR EL+P RIVR Sbjct 61 FADY-TGLHWFRTALDARPADEPIIDSVRAAVFAFPYDVEAVTKIAALRGEELDPGRIVR 119 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 H+R+V+ADFA+AI QL+RR+C + PD RL +AVTARC+AAAVFGAME WML +RSL Sbjct 120 HIRDVQADFAEAIAGQLQRRSCVVDPTPDQRLRVAVTARCIAAAVFGAMEVWMLADERSL 179 Query 181 GELARVCHVALESLRVGISDTWTTLTVSS 209 GELAR+CH ALESLR GI++ W VSS Sbjct 180 GELARMCHTALESLRAGITEAWVPGQVSS 208 >gi|296166958|ref|ZP_06849374.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897697|gb|EFG77287.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=206 Score = 318 bits (815), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 161/202 (80%), Positives = 174/202 (87%), Gaps = 1/202 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QT RSERTREAL QAALVRFLAQGVE TSAEQIA DAGVSLRTFYRHF+SKHDLL Sbjct 1 MVRPAQTVRSERTREALIQAALVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFKSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADY GL+WFRAALDARPA E IIDSVQ+AIFSFPYDV+AVTKIA+LR GEL+P RIVR Sbjct 61 FADY-TGLNWFRAALDARPAGEPIIDSVQSAIFSFPYDVEAVTKIAALRGGELDPVRIVR 119 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 HM+EV+ADFADAIQAQL RR+C D RL AV ARC+AA VFGAME WMLG DRSL Sbjct 120 HMQEVQADFADAIQAQLHRRSCAARETLDGRLRAAVIARCIAAGVFGAMEFWMLGDDRSL 179 Query 181 GELARVCHVALESLRVGISDTW 202 GELAR+CH ALESLR G +D+W Sbjct 180 GELARMCHAALESLRAGFTDSW 201 >gi|333992777|ref|YP_004525391.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] gi|333488745|gb|AEF38137.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] Length=192 Score = 276 bits (705), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 143/194 (74%), Positives = 158/194 (82%), Gaps = 5/194 (2%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 M R PQTARSERTREALRQAALVRFLAQGVE TSAEQIA DAGVSLRTFYRHF SKHDLL Sbjct 1 MPRAPQTARSERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFTSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGL WFR+AL RP E +++SVQAAIF+FPYDV+AVT+IA+LR EL+P RIVR Sbjct 61 FADYDAGLQWFRSALADRPPHEPMVESVQAAIFAFPYDVEAVTRIAALRAEELDPERIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 H+R+VEADFADA+ +LR P L IAVTARC+AAAVF AME WML DRSL Sbjct 121 HIRQVEADFADAVAERLR-----ATQGPADPLRIAVTARCIAAAVFAAMEVWMLDEDRSL 175 Query 181 GELARVCHVALESL 194 ELAR+C ALESL Sbjct 176 AELARMCRTALESL 189 >gi|108801469|ref|YP_641666.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119870622|ref|YP_940574.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|126437454|ref|YP_001073145.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|108771888|gb|ABG10610.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119696711|gb|ABL93784.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] gi|126237254|gb|ABO00655.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=198 Score = 270 bits (691), Expect = 8e-71, Method: Compositional matrix adjust. Identities = 142/194 (74%), Positives = 155/194 (80%), Gaps = 1/194 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QTARSERTREALRQAALVRFLAQGVE TSAEQIA DAGVSLRTFYRHF SKHDLL Sbjct 1 MVRPAQTARSERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFTSKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGL WFRAAL R DESII+SV +AI FPYD DAVTKIA+LR EL+ RIVR Sbjct 61 FADYDAGLQWFRAALAGRSPDESIIESVHSAILEFPYDADAVTKIAALRAEELDQGRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 H+R+VEADFA+A++ L R AG+ D RL V ARC+AAAVFGAME WM RSL Sbjct 121 HIRQVEADFAEAVEEHLTRDRAPAAGS-DERLRATVMARCIAAAVFGAMEMWMEDDPRSL 179 Query 181 GELARVCHVALESL 194 EL+R+C ALESL Sbjct 180 PELSRLCRTALESL 193 >gi|315442699|ref|YP_004075578.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|315261002|gb|ADT97743.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=201 Score = 268 bits (684), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 140/200 (70%), Positives = 158/200 (79%), Gaps = 1/200 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QT RSERTREALRQAA+VRFLAQGVE T+AEQIA DAGVSLRTFYRHF SKHDLL Sbjct 1 MVRPAQTVRSERTREALRQAAVVRFLAQGVEETTAEQIAADAGVSLRTFYRHFASKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGLHWFRAAL R ++ I+D+VQAAI + PYD AVTKIA++R EL+ RIVR Sbjct 61 FADYDAGLHWFRAALATRSPEDPILDTVQAAIMAAPYDDWAVTKIAAMRSQELDAGRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 H+R+VEADFADAI L R + G D R+ VTARC+AAAVFGAME WMLG D SL Sbjct 121 HIRQVEADFADAIDEHLARADGASPGT-DERMRTTVTARCIAAAVFGAMEVWMLGGDSSL 179 Query 181 GELARVCHVALESLRVGISD 200 EL R+C AL+ LR GI+D Sbjct 180 PELDRLCRHALDLLRTGIAD 199 >gi|145222268|ref|YP_001132946.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|145214754|gb|ABP44158.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] Length=201 Score = 267 bits (683), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 140/200 (70%), Positives = 158/200 (79%), Gaps = 1/200 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QT RSERTREALRQAA+VRFLAQGVE T+AEQIA DAGVSLRTFYRHF SKHDLL Sbjct 1 MVRPAQTVRSERTREALRQAAVVRFLAQGVEETTAEQIAADAGVSLRTFYRHFASKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGLHWFRAAL R ++ I+D+VQAAI + PYD AVTKIA++R EL+ RIVR Sbjct 61 FADYDAGLHWFRAALATRSPEDPILDTVQAAIMAAPYDDWAVTKIAAMRSQELDAGRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 H+R+VEADFADAI L R + G D R+ VTARC+AAAVFGAME WMLG D SL Sbjct 121 HIRQVEADFADAIDEHLARADGASPGT-DERMRTTVTARCIAAAVFGAMEVWMLGEDSSL 179 Query 181 GELARVCHVALESLRVGISD 200 EL R+C AL+ LR GI+D Sbjct 180 PELDRLCRHALDLLRTGIAD 199 >gi|120406025|ref|YP_955854.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119958843|gb|ABM15848.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=202 Score = 267 bits (682), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 139/200 (70%), Positives = 158/200 (79%), Gaps = 1/200 (0%) Query 1 MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 MVRP QTARSERTREALRQAA+VRFLAQGVE TSAEQIA DAGVSLRTFYRHF SKHDLL Sbjct 1 MVRPAQTARSERTREALRQAAVVRFLAQGVEDTSAEQIAADAGVSLRTFYRHFASKHDLL 60 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVR 120 FADYDAGLHWFR+AL AR +ESI +SVQ+AI + PY+ AVTKIA++R EL+ RIVR Sbjct 61 FADYDAGLHWFRSALAARSPEESIFESVQSAIMASPYEDWAVTKIAAMRAKELDTGRIVR 120 Query 121 HMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 H+R+VEADFA+A++ + G D R+ VTARC+AAAVFGAME WMLG DRSL Sbjct 121 HIRQVEADFAEAVEQHMAAAGAAAPGT-DERMRTTVTARCIAAAVFGAMEVWMLGEDRSL 179 Query 181 GELARVCHVALESLRVGISD 200 EL R+C AL LR GI D Sbjct 180 PELDRLCRQALTLLRSGIED 199 >gi|120402004|ref|YP_951833.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119954822|gb|ABM11827.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=199 Score = 117 bits (292), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 74/191 (39%), Positives = 108/191 (57%), Gaps = 5/191 (2%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 R TREALR+AAL F A+G + ++A AGV+ RTF+RHF +K +LF DY+ + Sbjct 11 RRRSTREALRRAALASFAARGFANVTVTELARAAGVTERTFFRHFPTKEAVLFQDYETQV 70 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEAD 128 W AAL RP ES+ D+V+AAI FPYD++ V + A+ R + RI H+R V++ Sbjct 71 EWLAAALARRPGSESVFDAVRAAIAEFPYDLEVVRQAATARSELISAERIAGHLRVVQSS 130 Query 129 FADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCH 188 FAD + +R R AG D L V +AAA+ A+E W G + + +L + Sbjct 131 FADVLTGHIRTR---YAGTADIDLVADVAGAALAAALVVAVEHW--GRNGCVDDLGEITS 185 Query 189 VALESLRVGIS 199 ++ LR G + Sbjct 186 ASMAVLRSGFA 196 >gi|118618342|ref|YP_906674.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|118570452|gb|ABL05203.1| transcriptional regulatory protein (TetR- family) [Mycobacterium ulcerans Agy99] Length=199 Score = 114 bits (285), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 70/192 (37%), Positives = 107/192 (56%), Gaps = 7/192 (3%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 R T EALR+AAL F +G + ++A +AGV+ RTF+RHF +K +LF DY+ L Sbjct 11 RRRSTHEALRRAALKSFARKGFAQVTVTELAREAGVTERTFFRHFPTKEAVLFQDYENQL 70 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEAD 128 W AL RP E + D+V A++ +FP+D++ V + A+ R + RI H+R V++ Sbjct 71 EWLARALAQRPVSEPLFDAVLASVAAFPHDLEVVRQAATARSELISADRIANHLRVVQSS 130 Query 129 FADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAW-MLGSDRSLGELARVC 187 FA + A +R R D+A + L V +AAA+ A+E W G LGEL Sbjct 131 FAQVLTAFVRNRYADVA---NVDLVAEVAGATIAAALVVAVENWGRYGCAEDLGEL---V 184 Query 188 HVALESLRVGIS 199 +L+ +R G++ Sbjct 185 AASLDLVRSGLA 196 >gi|183982816|ref|YP_001851107.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|183176142|gb|ACC41252.1| transcriptional regulatory protein (TetR- family) [Mycobacterium marinum M] Length=199 Score = 113 bits (283), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 67/191 (36%), Positives = 107/191 (57%), Gaps = 5/191 (2%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 R T EALR+AAL F +G + ++A +AGV+ RTF+RHF +K +LF DY+ L Sbjct 11 RRRSTHEALRRAALKSFACKGFAQVTVTELAREAGVTERTFFRHFPTKEAVLFQDYENQL 70 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEAD 128 W AL RP E + D+V A++ +FP+D++ V + A+ R + RI H+R V++ Sbjct 71 EWLAQALAQRPVSEPLFDAVLASVAAFPHDLEVVRQAATARSELISADRIANHLRVVQSS 130 Query 129 FADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCH 188 FA + A +R R D+A + L V +AAA+ A+E W G + +L + Sbjct 131 FAQVLTAFVRDRYADVA---NVDLVAEVAGATIAAALVVAVENW--GRNGCAVDLGELVA 185 Query 189 VALESLRVGIS 199 +L+ +R G++ Sbjct 186 ASLDLVRSGLA 196 >gi|296164937|ref|ZP_06847493.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899779|gb|EFG79229.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=199 Score = 113 bits (282), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 76/192 (40%), Positives = 111/192 (58%), Gaps = 7/192 (3%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 R T EALR+AAL F ++G + ++A +AGV+ RTF+RHF +K +LF DY+ L Sbjct 11 RRRSTHEALRRAALKSFASKGFTNVTVTELAREAGVTERTFFRHFPTKEAVLFQDYETQL 70 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEAD 128 W AL ARPA ES+ D+V A++ +FP+D + V + A+ R + RI H+R V++ Sbjct 71 EWLAEALAARPASESLFDAVLASVAAFPHDPEVVRQAATARAELISAERIAGHLRVVQSS 130 Query 129 FADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAW-MLGSDRSLGELARVC 187 FA + +R RN +A + L VT +AAA+ A+E W G R LGEL Sbjct 131 FARVLTDFVRGRNPQVA---NIDLLAEVTGSALAAALVVAVENWGRNGCTRDLGEL---V 184 Query 188 HVALESLRVGIS 199 +LE LR G++ Sbjct 185 ASSLELLRSGLA 196 >gi|118463380|ref|YP_881976.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|118164667|gb|ABK65564.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] Length=199 Score = 105 bits (261), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 55/138 (40%), Positives = 82/138 (60%), Gaps = 0/138 (0%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 R T EALRQAAL F +G + ++A +AGV+ RTF+RHF +K +LF DY+ L Sbjct 11 RRRSTHEALRQAALKSFARKGFANVTVTELAREAGVTERTFFRHFPTKESVLFQDYETQL 70 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEAD 128 W AL RP ES+ D+V A++ +FP+D++ V + A+ R + RI H+R V++ Sbjct 71 EWLAEALAQRPPSESLFDAVLASVAAFPHDLEVVRQAATARAELISAERIAGHLRVVQSS 130 Query 129 FADAIQAQLRRRNCDIAG 146 FA + +R RN +A Sbjct 131 FARVLTDFVRARNPQLAN 148 >gi|254821868|ref|ZP_05226869.1| transcriptional regulator, TetR family protein [Mycobacterium intracellulare ATCC 13950] Length=176 Score = 96.3 bits (238), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 61/175 (35%), Positives = 98/175 (56%), Gaps = 5/175 (2%) Query 25 FLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESI 84 F +G + ++A +AGV+ RTF+RHF +K +LF DY+ L W AL RP+ ES+ Sbjct 4 FARKGFANVTVTELAREAGVTERTFFRHFPTKEAVLFQDYETQLEWLAEALTQRPSSESL 63 Query 85 IDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDI 144 D+V A++ +FP+D++ V + A+ R + RI H+R V++ FA + +R+RN D Sbjct 64 FDAVLASVSAFPHDLEVVRQAATARAELISAERIAGHLRVVQSSFAGVLADFVRKRNPDT 123 Query 145 AGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALESLRVGIS 199 A D L V +AAA+ A+E W G G+L +L+ +R G++ Sbjct 124 A---DIDLAAEVAGSALAAALVAAVENW--GRKGCAGDLGADVAASLDLVRSGLA 173 >gi|342859565|ref|ZP_08716218.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342132697|gb|EGT85917.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=176 Score = 87.8 bits (216), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 59/175 (34%), Positives = 98/175 (56%), Gaps = 5/175 (2%) Query 25 FLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESI 84 F +G + ++A +AGV+ RTF+RHF +K +LF DY+ L W AL RP ES+ Sbjct 4 FAHKGFTNVTVTELAREAGVTERTFFRHFPTKEAVLFQDYETQLEWLAEALAQRPDSESL 63 Query 85 IDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDI 144 D+V A++ +FP+D++ V + A+ R + RI H+R V++ FA + +R+RN ++ Sbjct 64 FDAVLASVAAFPHDLEVVRQAAAARAELISAERIAGHLRVVQSSFARVLTDFVRQRNPEL 123 Query 145 AGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALESLRVGIS 199 P+ L V +AAA+ A+E W G G+L +L+ +R G++ Sbjct 124 ---PNIDLAAEVAGSAIAAALVAAVENW--GRRGCSGDLGADVASSLDLVRSGLA 173 >gi|302545755|ref|ZP_07298097.1| HTH-type transcriptional regulator TcmR (Tetracenomycin Ctranscriptional repressor) [Streptomyces hygroscopicus ATCC 53653] gi|302463373|gb|EFL26466.1| HTH-type transcriptional regulator TcmR (Tetracenomycin Ctranscriptional repressor) [Streptomyces himastatinicus ATCC 53653] Length=219 Score = 79.0 bits (193), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 66/216 (31%), Positives = 105/216 (49%), Gaps = 18/216 (8%) Query 2 VRPPQTA----RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKH 57 V PP T + +RTR AL ++AL F QG + T+ ++IAE VS RTF+R+F +K Sbjct 7 VAPPPTGLRERKKQRTRSALVRSALDLFTGQGYDHTTVDEIAESVDVSQRTFFRYFANKE 66 Query 58 DLLFADYDAGLHWFRAALDARPADESIIDSVQAAIF--------SFPYDVDAVTKIASLR 109 + FA D+ F AAL ARPA E+ + +++ A+ S V A + R Sbjct 67 QVAFATQDSAESHFFAALCARPAHEAPLAALRGAVLDAWSTMGDSVEQLVPAELHMRMYR 126 Query 110 RGELEPSRIVRHMREVEADFADAIQAQL-RRRNCDIAGAPDARLHIAVTARCVAAAVFGA 168 E P+ + H+R A+ + I +++ RR D++ P RL A+ + A G Sbjct 127 VIESTPALLAVHLRRT-AELEERIASEIARREGLDVSVDPRPRLLTAMFGGVIQIA--GK 183 Query 169 MEAWMLGSDRSLGELARVCHVALESLRVGISDTWTT 204 + W G D S L + L+ + +++ W T Sbjct 184 L--WGAGDDESTDALRDITAFHLDHVGPALAENWRT 217 >gi|345014806|ref|YP_004817160.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] gi|344041155|gb|AEM86880.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length=221 Score = 72.4 bits (176), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 66/213 (31%), Positives = 104/213 (49%), Gaps = 21/213 (9%) Query 4 PPQTAR---SERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLL 60 PP R +RTR AL ++AL F QG E T+ ++IAE VS RTF+R+F +K ++ Sbjct 14 PPPGLRERKKQRTRNALVRSALELFTRQGYEHTTVDEIAEAVEVSQRTFFRYFANKEEVA 73 Query 61 FADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDV-DAVTKIAS-------LRRGE 112 FA ++ F AAL RPADE+ + +++ A+ + DA+ ++ R E Sbjct 74 FASQESAECHFFAALCGRPADEAPLAALRGAVLDAWGSIGDAIEQMVPPELHMRMYRVIE 133 Query 113 LEPSRIVRHMR---EVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAM 169 PS + H+R E+E A I RR DI P RL +A+ + + V G + Sbjct 134 STPSLLAVHLRRTAEMEERLASEIA---RREGLDIDADPRPRLVVAMFSGVI--RVSGKL 188 Query 170 EAWMLGSDRSLGELARVCHVALESLRVGISDTW 202 W G + S+ L + L+ + ++ W Sbjct 189 --WGEGEEDSMVTLRDLTAFHLDYVGPTLAGQW 219 >gi|730916|sp|P39885.1|TCMR_STRGA RecName: Full=HTH-type transcriptional regulator tcmR; AltName: Full=Tetracenomycin C transcriptional repressor Length=226 Score = 70.9 bits (172), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 68/202 (34%), Positives = 93/202 (47%), Gaps = 18/202 (8%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 RTR+ L + AL FLAQG E T+ EQIAE V RTF+RHF SK ++ A F Sbjct 27 RTRDQLIREALELFLAQGYEHTTVEQIAEAVEVHPRTFFRHFASKEEVALTPISAIDEAF 86 Query 72 RAALDARPADESIIDSVQA---AIFSFPYD-----VDAVTKIASLRRGELEPSRIVRHMR 123 AAL+ RPA E+ + ++ A+ D VD +A +R E P + ++R Sbjct 87 LAALEVRPAGENPLQAMSGAFRAVLGRVRDGELEGVDGALHMAMMRLVERTPGLLAEYLR 146 Query 124 ---EVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 E+E A I A R D+ R +AV + V V W L +D L Sbjct 147 RSEEMEGRLARIIAA---REGVDLDDDFRPRFIVAVF-KAVGRVV---SREWYLRADTDL 199 Query 181 GELARVCHVALESLRVGISDTW 202 L+ AL+SLR + W Sbjct 200 EALSVAFESALDSLRPELFADW 221 >gi|153489|gb|AAA67508.1| tetracenomycin C resistance and export gene repressor [Streptomyces glaucescens] Length=227 Score = 70.9 bits (172), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 68/202 (34%), Positives = 93/202 (47%), Gaps = 18/202 (8%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 RTR+ L + AL FLAQG E T+ EQIAE V RTF+RHF SK ++ A F Sbjct 28 RTRDQLIREALELFLAQGYEHTTVEQIAEAVEVHPRTFFRHFASKEEVALTPISAIDEAF 87 Query 72 RAALDARPADESIIDSVQA---AIFSFPYD-----VDAVTKIASLRRGELEPSRIVRHMR 123 AAL+ RPA E+ + ++ A+ D VD +A +R E P + ++R Sbjct 88 LAALEVRPAGENPLQAMSGAFRAVLGRVRDGELEGVDGALHMAMMRLVERTPGLLAEYLR 147 Query 124 ---EVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSL 180 E+E A I A R D+ R +AV + V V W L +D L Sbjct 148 RSEEMEGRLARIIAA---REGVDLDDDFRPRFIVAVF-KAVGRVV---SREWYLRADTDL 200 Query 181 GELARVCHVALESLRVGISDTW 202 L+ AL+SLR + W Sbjct 201 EALSVAFESALDSLRPELFADW 222 >gi|229490652|ref|ZP_04384490.1| transcriptional regulator, AcrR family [Rhodococcus erythropolis SK121] gi|229322472|gb|EEN88255.1| transcriptional regulator, AcrR family [Rhodococcus erythropolis SK121] Length=199 Score = 69.7 bits (169), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 60/203 (30%), Positives = 96/203 (48%), Gaps = 30/203 (14%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 R T+E + + F G S +QIA+ AG++ RTF+R+F SK+ + + D+D L Sbjct 14 RPSTTKEGISTIGIELFSTVGFNEVSVDQIADAAGIARRTFFRYFPSKNAVPWGDFDGHL 73 Query 69 HWFRAALDARPADESIIDSVQAAIF---SFPYDVDAVTKI---ASLRRGELEPSRIVRH- 121 R LD+ PAD ++D++++A+ +FP + AV + L L+ +V + Sbjct 74 DEMREHLDSLPADIPLVDALESALLTFNTFPPEETAVHRKRMELILEVPTLQAYSVVMYE 133 Query 122 -MREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFG----AMEAWMLGS 176 R+V AD+ RR N + + R V + G A E W+ + Sbjct 134 GWRQVVADYV------ARRMNLEPSDH---------GPRTVGYLLLGVAMSAYEQWL--T 176 Query 177 DRSLGELARVCHVALESLRVGIS 199 D SL EL + +SLR GIS Sbjct 177 DDSL-ELPELLKTGTQSLRTGIS 198 >gi|328882236|emb|CCA55475.1| Transcriptional regulator, TetR family [Streptomyces venezuelae ATCC 10712] Length=211 Score = 69.3 bits (168), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 62/206 (31%), Positives = 97/206 (48%), Gaps = 20/206 (9%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 + +RTR+ L + AL F QG E T+ ++I + VS RTF+R+F SK ++ FA Sbjct 10 KKQRTRDELTRVALQLFTTQGYERTTVDEIVDAVEVSQRTFFRYFSSKEEVAFAVQHMVE 69 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDV--DAVTKIA-------SLRRGELEPSRIV 119 F AL RP DE D+++ A+ +D DA+T++ + + E P+ + Sbjct 70 ERFVEALRVRPPDEGPFDAMRNAVLC-AWDTIGDAITEVVPVELYLRTFQMIESTPALLA 128 Query 120 RHMR---EVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGS 176 H+R E+E A I R D+ P R IAV A V G + W G+ Sbjct 129 VHLRRSTEMEEIIAGIIAG---REGLDVDADPRPR--IAVAAFSGVMRVTGQL--WGRGT 181 Query 177 DRSLGELARVCHVALESLRVGISDTW 202 D+SL + + L+ L ++ W Sbjct 182 DQSLEAIRGLTEEYLDHLGPALAPRW 207 >gi|226305285|ref|YP_002765243.1| TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|226184400|dbj|BAH32504.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis PR4] Length=199 Score = 69.3 bits (168), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 60/203 (30%), Positives = 95/203 (47%), Gaps = 30/203 (14%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 R TRE + + F G S +QIA+ AG++ RTF+R+F SK+ + + D+D L Sbjct 14 RPSTTREGISTIGIELFSTVGFNEVSVDQIADAAGIARRTFFRYFPSKNAVPWGDFDGHL 73 Query 69 HWFRAALDARPADESIIDSVQAAIF---SFPYDVDAVTKIAS---LRRGELEPSRIVRH- 121 R LD+ PAD ++D++++A+ +FP + AV + L L+ +V + Sbjct 74 DEMREHLDSLPADIPLVDALESALLTFNTFPPEETAVHRKRMELILEVPTLQAYSVVMYE 133 Query 122 -MREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFG----AMEAWMLGS 176 R+V AD+ RR N + R V + G A E W+ + Sbjct 134 GWRQVVADYV------ARRMNLEPTDH---------GPRTVGYLLLGVAMSAYEQWL--T 176 Query 177 DRSLGELARVCHVALESLRVGIS 199 D SL EL + +SLR GI+ Sbjct 177 DDSL-ELPELLKTGTQSLRTGIT 198 >gi|291455176|ref|ZP_06594566.1| TetR-family transcriptional regulator [Streptomyces albus J1074] gi|291358125|gb|EFE85027.1| TetR-family transcriptional regulator [Streptomyces albus J1074] Length=275 Score = 68.9 bits (167), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 36/77 (47%), Positives = 50/77 (65%), Gaps = 0/77 (0%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 + R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK + +FAD+D L Sbjct 35 KMRRELSAAAMELFATKGYEATTVDEIAAAAGVARRTFFRHFRSKEEAIFADHDDTLTRV 94 Query 72 RAALDARPADESIIDSV 88 A L+A PA E +D+V Sbjct 95 EAVLNAAPAHEHPLDTV 111 >gi|302534244|ref|ZP_07286586.1| TetR family transcriptional regulator [Streptomyces sp. C] gi|302443139|gb|EFL14955.1| TetR family transcriptional regulator [Streptomyces sp. C] Length=220 Score = 67.8 bits (164), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 63/205 (31%), Positives = 106/205 (52%), Gaps = 18/205 (8%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 + RTR+AL +AAL+ F++QG E T+ ++I + VS RTF+R+F +K ++ FA D Sbjct 16 KKRRTRDALLRAALLLFVSQGYERTTVDEITDTVEVSQRTFFRYFANKEEVAFAVQDVVE 75 Query 69 HWFRAALDARPADESIIDSVQAAIF-SFPYDVDAVTKIA-------SLRRGELEPSRIVR 120 F AAL RPA E+ +++++ A+ S+ +A++ + S R E P+ + Sbjct 76 SHFLAALRTRPASEAPLEALRNAVLVSWDTVEEAISDVVPVDLYMRSYRLIESTPALLAV 135 Query 121 HMR---EVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSD 177 H+R E+E + A I A R D+ P R +AV A V G + W G D Sbjct 136 HLRRSTELEEEIARLIAA---REGLDLDADP--RPRVAVAAFSGVMRVTGRL--WGQGED 188 Query 178 RSLGELARVCHVALESLRVGISDTW 202 S+ + R+ L+ + +++ W Sbjct 189 TSVAAIRRMTVAHLDQIGPALAEDW 213 >gi|291436189|ref|ZP_06575579.1| transcriptional regulator [Streptomyces ghanaensis ATCC 14672] gi|291339084|gb|EFE66040.1| transcriptional regulator [Streptomyces ghanaensis ATCC 14672] Length=271 Score = 67.4 bits (163), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 39/92 (43%), Positives = 54/92 (59%), Gaps = 7/92 (7%) Query 4 PPQTARSERT-------REALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSK 56 PP++A R R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK Sbjct 16 PPESAAGSRAAAQRLKMRRELAAAAMELFATKGYEATTVDEIAAAAGVARRTFFRHFRSK 75 Query 57 HDLLFADYDAGLHWFRAALDARPADESIIDSV 88 + +F D+D L A L+A PA E +D+V Sbjct 76 EEAIFPDHDDTLVRAEAVLNAAPAHEHPLDTV 107 >gi|302557327|ref|ZP_07309669.1| TetR-family transcriptional regulator [Streptomyces griseoflavus Tu4000] gi|302474945|gb|EFL38038.1| TetR-family transcriptional regulator [Streptomyces griseoflavus Tu4000] Length=270 Score = 67.4 bits (163), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 39/92 (43%), Positives = 54/92 (59%), Gaps = 7/92 (7%) Query 4 PPQTARSERT-------REALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSK 56 PP++A R R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK Sbjct 16 PPESAAGSRAAAQRLKMRRELAAAAMELFATKGYEATTVDEIAAAAGVARRTFFRHFRSK 75 Query 57 HDLLFADYDAGLHWFRAALDARPADESIIDSV 88 + +F D+D L A L+A PA E +D+V Sbjct 76 EEAIFPDHDDTLVRAEAVLNAAPAHEHPLDTV 107 >gi|297194570|ref|ZP_06911968.1| TetR-family transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] gi|197722483|gb|EDY66391.1| TetR-family transcriptional regulator [Streptomyces pristinaespiralis ATCC 25486] Length=221 Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 60/208 (29%), Positives = 103/208 (50%), Gaps = 24/208 (11%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 + +RTR+AL + AL F QG E T+ ++IA+ VS RTF+R+F SK ++ FA + Sbjct 13 KKQRTRDALVRVALELFTTQGYERTTVDEIADTVEVSQRTFFRYFASKEEVAFAVQEILE 72 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDV--DAVTKIA-------SLRRGELEPSRIV 119 + AL ARPA+E +++++ A+F+ +D +AV +I S + E P+ + Sbjct 73 AHYAVALRARPAEEGPLEALRNAVFA-AWDAIGEAVEEIVPLDLYMRSFQMIESTPALLA 131 Query 120 RHMREVEADFADAIQAQL-RRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEA----WML 174 ++R +A+ A + R D+ P R+ + AA G M A W Sbjct 132 AYLRRSTVT-EEALAALIAEREGLDVNTDPRPRVAV--------AAFSGVMRATGRLWGQ 182 Query 175 GSDRSLGELARVCHVALESLRVGISDTW 202 G+D S+ + + L+ L ++ W Sbjct 183 GADPSIEAIRSLTETFLDHLGPALAQNW 210 >gi|294629135|ref|ZP_06707695.1| HTH-type transcriptional regulator TcmR [Streptomyces sp. e14] gi|292832468|gb|EFF90817.1| HTH-type transcriptional regulator TcmR [Streptomyces sp. e14] Length=264 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 63/212 (30%), Positives = 96/212 (46%), Gaps = 28/212 (13%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 + RTR+AL +A+L F +G E T+ + IAE VS RTF+RHF K + FA D Sbjct 23 KKRRTRDALLRASLELFTTKGYEQTTVDDIAEAVDVSQRTFFRHFPGKEEAAFAVQDTVE 82 Query 69 HWFRAALDARPADESIIDSVQAAIF-SFPYDVDAVTKIASLRRG-------ELEPSRIVR 120 F AL ARP E+ +++++ A+ S+ DAV + + E P+ + Sbjct 83 AHFVQALRARPRHETPLEALRRAVLDSWDTISDAVESVVPVELYLRMFWVIESTPALLAA 142 Query 121 HMR---EVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAM-----EAW 172 ++R E E + A + A R D+ P RL A AVFG + W Sbjct 143 YLRRSVETEEEIARLLAA---REGLDVDADPRPRL---------AVAVFGGVMRVTGRQW 190 Query 173 MLGSDRSLGELARVCHVALESLRVGISDTWTT 204 G D SL + + L+ + ++ W T Sbjct 191 STGEDFSLAAIRALTAAHLDQIGPALAGNWRT 222 >gi|302541632|ref|ZP_07293974.1| putative transcriptional regulator [Streptomyces hygroscopicus ATCC 53653] gi|302459250|gb|EFL22343.1| putative transcriptional regulator [Streptomyces himastatinicus ATCC 53653] Length=301 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 36/75 (48%), Positives = 48/75 (64%), Gaps = 0/75 (0%) Query 14 REALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRA 73 R L AA+ F QG EAT+ ++IA AGV+ RTF+RHFRSK + +F D+D L A Sbjct 70 RRKLAAAAMELFATQGYEATTVDEIAARAGVARRTFFRHFRSKEEAIFPDHDDTLVRAAA 129 Query 74 ALDARPADESIIDSV 88 LDA P E+ +D+V Sbjct 130 VLDAAPPHENPLDTV 144 >gi|337768835|emb|CCB77548.1| conserved protein of unknown function [Streptomyces cattleya NRRL 8057] Length=262 Score = 67.0 bits (162), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 37/85 (44%), Positives = 53/85 (63%), Gaps = 0/85 (0%) Query 4 PPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFAD 63 P TA+ R R+ L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK + +F D Sbjct 8 PRTTAQRHRVRQELATAAMRLFSTKGYEATTVDEIAAAAGVARRTFFRHFRSKEEAIFPD 67 Query 64 YDAGLHWFRAALDARPADESIIDSV 88 +D L +A LD+ E +D+V Sbjct 68 HDDTLVRVQAVLDSADPAEHPLDTV 92 >gi|21224778|ref|NP_630557.1| transcriptional regulator [Streptomyces coelicolor A3(2)] gi|289767942|ref|ZP_06527320.1| transcriptional regulator [Streptomyces lividans TK24] gi|4154069|emb|CAA22722.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)] gi|289698141|gb|EFD65570.1| transcriptional regulator [Streptomyces lividans TK24] Length=272 Score = 66.6 bits (161), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 35/77 (46%), Positives = 49/77 (64%), Gaps = 0/77 (0%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 + R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK + +F D+D L Sbjct 31 KMRRELAAAAMELFATKGYEATTVDEIAAQAGVARRTFFRHFRSKEEAIFPDHDDTLVRA 90 Query 72 RAALDARPADESIIDSV 88 A L+A PA E +D+V Sbjct 91 EAVLNAAPAHEHPLDTV 107 >gi|337765495|emb|CCB74204.1| HTH-type transcriptional regulator tcmR [Streptomyces cattleya NRRL 8057] Length=223 Score = 66.2 bits (160), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 60/211 (29%), Positives = 95/211 (46%), Gaps = 22/211 (10%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 + +RTR+AL +AA+ F +QG E T+ ++IAE VS RTF+R+F +K A D Sbjct 21 KKQRTRDALVRAAMQLFTSQGFERTTVDEIAEAVEVSQRTFFRYFTNKEHAALALDDLIE 80 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEAD 128 F AAL RPADE +++++ A+ DV E+ P + M +V Sbjct 81 ERFLAALRERPADEPPLEALRHAVLGVWDDVSTAIH-------EVVPIDLYMRMYQVIES 133 Query 129 FADAIQAQLRR-------------RNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLG 175 + A+LRR R + D R + V A + A E W Sbjct 134 TPALLSARLRREAQMETRITAEIARRTGLDPRTDLRPRVLVAA--FGGVIRAASEHWGHC 191 Query 176 SDRSLGELARVCHVALESLRVGISDTWTTLT 206 S+ S+ + LE+L ++ +W ++T Sbjct 192 SEGSVAAMRSSFRRHLETLGPALAGSWQSVT 222 >gi|254382183|ref|ZP_04997544.1| conserved hypothetical protein [Streptomyces sp. Mg1] gi|194341089|gb|EDX22055.1| conserved hypothetical protein [Streptomyces sp. Mg1] Length=273 Score = 66.2 bits (160), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 35/77 (46%), Positives = 48/77 (63%), Gaps = 0/77 (0%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 + R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK + +F D+D L Sbjct 32 KMRRELAAAAMELFATKGYEATTVDEIAATAGVARRTFFRHFRSKEEAIFPDHDDTLTRA 91 Query 72 RAALDARPADESIIDSV 88 A LD PA E +D+V Sbjct 92 EAVLDVAPAHEHPLDTV 108 >gi|302537843|ref|ZP_07290185.1| TetR family transcriptional regulator [Streptomyces sp. C] gi|302446738|gb|EFL18554.1| TetR family transcriptional regulator [Streptomyces sp. C] Length=277 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 35/77 (46%), Positives = 48/77 (63%), Gaps = 0/77 (0%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 + R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK + +F D+D L Sbjct 38 KMRRELAAAAMELFATKGYEATTVDEIAATAGVARRTFFRHFRSKEEAIFPDHDDTLTRA 97 Query 72 RAALDARPADESIIDSV 88 A LD PA E +D+V Sbjct 98 EAVLDVAPAHEHPLDTV 114 >gi|302518798|ref|ZP_07271140.1| TetR-family transcriptional regulator [Streptomyces sp. SPB78] gi|318058647|ref|ZP_07977370.1| TetR family transcriptional regulator [Streptomyces sp. SA3_actG] gi|318076811|ref|ZP_07984143.1| TetR family transcriptional regulator [Streptomyces sp. SA3_actF] gi|302427693|gb|EFK99508.1| TetR-family transcriptional regulator [Streptomyces sp. SPB78] Length=272 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 37/85 (44%), Positives = 53/85 (63%), Gaps = 0/85 (0%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 + RTRE L + AL F A+G E T+ ++IA A VS RTF+R+F +K D+ A + Sbjct 23 KKTRTRERLLRTALELFAARGYERTTVDEIAARAEVSTRTFFRYFATKEDVALATQELIE 82 Query 69 HWFRAALDARPADESIIDSVQAAIF 93 WF AL ARPADES + +++ A+ Sbjct 83 RWFLQALRARPADESPVLALRRAVL 107 >gi|226365537|ref|YP_002783320.1| TetR family transcriptional regulator [Rhodococcus opacus B4] gi|226244027|dbj|BAH54375.1| putative TetR family transcriptional regulator [Rhodococcus opacus B4] Length=205 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 32/87 (37%), Positives = 53/87 (61%), Gaps = 0/87 (0%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 R T++ + + F QG +ATS +++AE +G++ RT +R+F SK+ + + D+DA L Sbjct 14 RPSTTQDRISTVGIELFTEQGFDATSVDEVAEASGIARRTLFRYFPSKNAIPWGDFDAHL 73 Query 69 HWFRAALDARPADESIIDSVQAAIFSF 95 RA L A+P D I+D + AA+ F Sbjct 74 AEMRAQLAAQPGDIPIVDGLTAALLQF 100 >gi|329940347|ref|ZP_08289628.1| transcriptional regulator [Streptomyces griseoaurantiacus M045] gi|329300408|gb|EGG44305.1| transcriptional regulator [Streptomyces griseoaurantiacus M045] Length=279 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 35/77 (46%), Positives = 49/77 (64%), Gaps = 0/77 (0%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 + R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK + +F D+D L Sbjct 37 KMRRELAAAAMELFSTKGYEATTVDEIAAAAGVARRTFFRHFRSKEEAIFPDHDDTLVRV 96 Query 72 RAALDARPADESIIDSV 88 A L+A PA E +D+V Sbjct 97 EAVLNAAPAHEHPLDTV 113 >gi|302555237|ref|ZP_07307579.1| TetR-family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] gi|302472855|gb|EFL35948.1| TetR-family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] Length=269 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 35/77 (46%), Positives = 49/77 (64%), Gaps = 0/77 (0%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 + R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK + +F D+D L Sbjct 31 KMRRELAAAAMELFATKGYEATTVDEIAAQAGVARRTFFRHFRSKEEAIFPDHDDTLIRA 90 Query 72 RAALDARPADESIIDSV 88 A L+A PA E +D+V Sbjct 91 EAVLNAAPAHEHPLDTV 107 >gi|345010150|ref|YP_004812504.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] gi|344036499|gb|AEM82224.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length=274 Score = 65.9 bits (159), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 36/75 (48%), Positives = 47/75 (63%), Gaps = 0/75 (0%) Query 14 REALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRA 73 R L AA+ F QG EAT+ ++IA AGV+ RTF+RHFRSK + +F D+D L A Sbjct 38 RRKLAAAAMELFATQGYEATTVDEIAARAGVARRTFFRHFRSKEEAIFPDHDDTLVRAAA 97 Query 74 ALDARPADESIIDSV 88 LDA P E +D+V Sbjct 98 VLDAAPPHEHPLDTV 112 >gi|254390172|ref|ZP_05005392.1| HTH-type transcriptional regulator tcmR [Streptomyces clavuligerus ATCC 27064] gi|294817163|ref|ZP_06775805.1| Putative TetR-family transcriptional regulator [Streptomyces clavuligerus ATCC 27064] gi|326446053|ref|ZP_08220787.1| TetR family transcriptional regulator [Streptomyces clavuligerus ATCC 27064] gi|197703879|gb|EDY49691.1| HTH-type transcriptional regulator tcmR [Streptomyces clavuligerus ATCC 27064] gi|294321978|gb|EFG04113.1| Putative TetR-family transcriptional regulator [Streptomyces clavuligerus ATCC 27064] Length=214 Score = 65.9 bits (159), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 61/208 (30%), Positives = 101/208 (49%), Gaps = 20/208 (9%) Query 9 RSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGL 68 + +RTR+AL +AAL F +G EAT+ ++IAE VS RTFYR++ +K D+ FA Sbjct 15 KKQRTRDALARAALELFTTKGFEATTVDEIAEAVDVSQRTFYRYYPAKEDVAFAVQAISE 74 Query 69 HWFRAALDARPADESIIDSVQAAIFSFPYDV--DAVTKIASLRRG-------ELEPSRI- 118 F AL ARPA E+ ++++ A+ + +D +AV ++ + E P+ + Sbjct 75 DHFVEALRARPAHEAPFEAMRNAMLA-AWDTIEEAVGEVVPVELHMRTYQVIESTPALLA 133 Query 119 --VRHMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGS 176 +R E E A + A R D+ P R+ +A +A+ A W Sbjct 134 VRIRRSLETEEKIARILAA---REGLDLDTDPRPRIAVA----AFGSAMQVADRIWNARG 186 Query 177 DRSLGELARVCHVALESLRVGISDTWTT 204 D S + + L+ LR ++++W T Sbjct 187 DHSREAIRAIAADCLDQLRPAVAESWRT 214 >gi|29828452|ref|NP_823086.1| TetR family transcriptional regulator [Streptomyces avermitilis MA-4680] gi|29605555|dbj|BAC69621.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length=271 Score = 65.9 bits (159), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 35/77 (46%), Positives = 49/77 (64%), Gaps = 0/77 (0%) Query 12 RTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF 71 + R L AA+ F +G EAT+ ++IA AGV+ RTF+RHFRSK + +F D+D L Sbjct 31 KMRRELAAAAMELFATKGYEATTVDEIAAAAGVARRTFFRHFRSKEEAIFPDHDDTLVRA 90 Query 72 RAALDARPADESIIDSV 88 A L+A PA E +D+V Sbjct 91 EAVLNAAPAHEHPLDTV 107 Lambda K H 0.324 0.132 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 242769087144 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40