BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3855

Length=216
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|254574836|pdb|3G1O|A  Chain A, Ethr From Mycobacterium Tubercu...   439    1e-121
gi|254574834|pdb|3G1L|A  Chain A, Ethr From Mycobacterium Tubercu...   439    2e-121
gi|56966246|pdb|1U9O|A  Chain A, Crystal Structure Of The Transcr...   439    2e-121
gi|254574835|pdb|3G1M|A  Chain A, Ethr From Mycobacterium Tubercu...   437    5e-121
gi|15610991|ref|NP_218372.1|  transcriptional regulatory represso...   437    7e-121
gi|317457510|gb|ADV29776.1|  transcriptional regulatory repressor...   435    2e-120
gi|317457508|gb|ADV29775.1|  transcriptional regulatory repressor...   434    3e-120
gi|56966245|pdb|1U9N|A  Chain A, Crystal Structure Of The Transcr...   427    6e-118
gi|240168331|ref|ZP_04746990.1|  transcriptional regulatory repre...   360    8e-98 
gi|183985374|ref|YP_001853665.1|  TetR family transcriptional reg...   343    1e-92 
gi|118620041|ref|YP_908373.1|  TetR family transcriptional regula...   342    3e-92 
gi|15826909|ref|NP_301172.1|  transcriptional regulator [Mycobact...   308    3e-82 
gi|254821452|ref|ZP_05226453.1|  transcriptional regulatory repre...   280    1e-73 
gi|108802021|ref|YP_642218.1|  TetR family transcriptional regula...   279    2e-73 
gi|119871173|ref|YP_941125.1|  TetR family transcriptional regula...   278    4e-73 
gi|126438000|ref|YP_001073691.1|  TetR family transcriptional reg...   259    2e-67 
gi|120406626|ref|YP_956455.1|  TetR family transcriptional regula...   258    3e-67 
gi|41406277|ref|NP_959113.1|  hypothetical protein MAP0179c [Myco...   250    1e-64 
gi|342860108|ref|ZP_08716760.1|  TetR family transcriptional regu...   249    2e-64 
gi|254773230|ref|ZP_05214746.1|  hypothetical protein MaviaA2_009...   249    2e-64 
gi|118462741|ref|YP_879467.1|  TetR family transcriptional regula...   247    8e-64 
gi|336461862|gb|EGO40717.1|  transcriptional regulator [Mycobacte...   247    8e-64 
gi|118468283|ref|YP_890654.1|  TetR family transcriptional regula...   246    2e-63 
gi|296166985|ref|ZP_06849399.1|  TetR family transcriptional regu...   246    2e-63 
gi|333992812|ref|YP_004525426.1|  TetR family transcriptional reg...   239    2e-61 
gi|315446705|ref|YP_004079584.1|  TetR family transcriptional reg...   231    4e-59 
gi|15827524|ref|NP_301787.1|  TetR family transcriptional regulat...   229    2e-58 
gi|145221557|ref|YP_001132235.1|  TetR family transcriptional reg...   227    9e-58 
gi|296170917|ref|ZP_06852454.1|  TetR family transcriptional regu...   226    2e-57 
gi|342858547|ref|ZP_08715202.1|  TetR family transcriptional regu...   225    3e-57 
gi|159038126|ref|YP_001537379.1|  TetR family transcriptional reg...   225    3e-57 
gi|169628081|ref|YP_001701730.1|  TetR family transcriptional reg...   223    2e-56 
gi|302867732|ref|YP_003836369.1|  regulatory protein TetR [Microm...   221    4e-56 
gi|111026296|ref|YP_708579.1|  TetR family transcriptional regula...  96.7    2e-18 
gi|333027676|ref|ZP_08455740.1|  putative short chain dehydrogena...  94.7    8e-18 
gi|298246923|ref|ZP_06970728.1|  transcriptional regulator, TetR ...  94.4    9e-18 
gi|302556436|ref|ZP_07308778.1|  TetR family transcriptional regu...  90.5    2e-16 
gi|21218783|ref|NP_624562.1|  TetR family transcriptional regulat...  89.4    3e-16 
gi|118462781|ref|YP_884182.1|  TetR family transcriptional regula...  88.6    6e-16 
gi|316305584|gb|ADU56258.1|  putative tetR-family transcriptional...  88.2    7e-16 
gi|319951456|ref|ZP_08025266.1|  TetR family transcriptional regu...  88.2    8e-16 
gi|325673017|ref|ZP_08152711.1|  transcriptional regulator [Rhodo...  85.5    5e-15 
gi|312141723|ref|YP_004009059.1|  tetr family transcriptional reg...  85.5    5e-15 
gi|320012916|gb|ADW07766.1|  regulatory protein TetR [Streptomyce...  85.1    5e-15 
gi|256397954|ref|YP_003119518.1|  TetR family transcriptional reg...  84.7    8e-15 
gi|320012886|gb|ADW07736.1|  regulatory protein TetR [Streptomyce...  84.3    1e-14 
gi|294649677|ref|ZP_06727088.1|  transcriptional regulator [Acine...  84.3    1e-14 
gi|50085844|ref|YP_047354.1|  transcriptional regulator [Acinetob...  83.2    2e-14 
gi|302546925|ref|ZP_07299267.1|  TetR-family transcriptional regu...  82.4    4e-14 
gi|163840689|ref|YP_001625094.1|  TetR family transcriptional reg...  82.4    4e-14 


>gi|254574836|pdb|3G1O|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm14500
Length=255

 Score =  439 bits (1128),  Expect = 1e-121, Method: Compositional matrix adjust.
 Identities = 215/216 (99%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            +TTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
Sbjct  20   MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  79

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV
Sbjct  80   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  139

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
Sbjct  140  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  199

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Sbjct  200  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  235


>gi|254574834|pdb|3G1L|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm14744
Length=256

 Score =  439 bits (1128),  Expect = 2e-121, Method: Compositional matrix adjust.
 Identities = 215/216 (99%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            +TTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
Sbjct  21   MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  80

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV
Sbjct  81   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  140

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
Sbjct  141  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  200

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Sbjct  201  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  236


>gi|56966246|pdb|1U9O|A Chain A, Crystal Structure Of The Transcriptional Regulator Ethr 
In A Ligand Bound Conformation
 gi|56966247|pdb|1U9O|B Chain B, Crystal Structure Of The Transcriptional Regulator Ethr 
In A Ligand Bound Conformation
Length=236

 Score =  439 bits (1128),  Expect = 2e-121, Method: Compositional matrix adjust.
 Identities = 216/216 (100%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
Sbjct  21   VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  80

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV
Sbjct  81   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  140

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
Sbjct  141  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  200

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Sbjct  201  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  236


>gi|254574835|pdb|3G1M|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm31381
 gi|305677856|pdb|3O8G|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm14801
 gi|305677857|pdb|3O8H|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm14950
Length=236

 Score =  437 bits (1124),  Expect = 5e-121, Method: Compositional matrix adjust.
 Identities = 215/216 (99%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            +TTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
Sbjct  21   MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  80

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV
Sbjct  81   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  140

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
Sbjct  141  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  200

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Sbjct  201  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  236


>gi|15610991|ref|NP_218372.1| transcriptional regulatory repressor protein (TETR-family) ETHR 
[Mycobacterium tuberculosis H37Rv]
 gi|15843486|ref|NP_338523.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
CDC1551]
 gi|31795029|ref|NP_857522.1| transcriptional regulatory repressor protein (TETR-family) ETHR 
[Mycobacterium bovis AF2122/97]
 83 more sequence titles
 Length=216

 Score =  437 bits (1123),  Expect = 7e-121, Method: Compositional matrix adjust.
 Identities = 215/216 (99%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            +TTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
Sbjct  1    MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV
Sbjct  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
Sbjct  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Sbjct  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216


>gi|317457510|gb|ADV29776.1| transcriptional regulatory repressor protein EthR [Mycobacterium 
tuberculosis]
Length=216

 Score =  435 bits (1118),  Expect = 2e-120, Method: Compositional matrix adjust.
 Identities = 214/216 (99%), Positives = 215/216 (99%), Gaps = 0/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            +TTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
Sbjct  1    MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENP DTDRENMWRTGINVFFETFGSHKAV
Sbjct  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPTDTDRENMWRTGINVFFETFGSHKAV  120

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
Sbjct  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Sbjct  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216


>gi|317457508|gb|ADV29775.1| transcriptional regulatory repressor protein EthR [Mycobacterium 
tuberculosis]
Length=216

 Score =  434 bits (1117),  Expect = 3e-120, Method: Compositional matrix adjust.
 Identities = 214/216 (99%), Positives = 215/216 (99%), Gaps = 0/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            +TTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
Sbjct  1    MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINV FETFGSHKAV
Sbjct  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVLFETFGSHKAV  120

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
Sbjct  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Sbjct  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216


>gi|56966245|pdb|1U9N|A Chain A, Crystal Structure Of The Transcriptional Regulator Ethr 
In A Ligand Bound Conformation Opens Therapeutic Perspectives 
Against Tuberculosis And Leprosy
Length=236

 Score =  427 bits (1098),  Expect = 6e-118, Method: Compositional matrix adjust.
 Identities = 212/216 (99%), Positives = 212/216 (99%), Gaps = 0/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT
Sbjct  21   VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  80

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVNQAD ALQTLAENPADTDREN WRTGINVFFETFGSHKAV
Sbjct  81   FYFYFPSKEAVLLTLLDRVVNQADXALQTLAENPADTDRENXWRTGINVFFETFGSHKAV  140

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATSVEVAELWSTF QKWIAYTAAVIDAERDRGAAPRTLPAHELATALNL NE
Sbjct  141  TRAGQAARATSVEVAELWSTFXQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLXNE  200

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Sbjct  201  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  236


>gi|240168331|ref|ZP_04746990.1| transcriptional regulatory repressor protein [Mycobacterium kansasii 
ATCC 12478]
Length=215

 Score =  360 bits (924),  Expect = 8e-98, Method: Compositional matrix adjust.
 Identities = 179/216 (83%), Positives = 189/216 (88%), Gaps = 1/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            + TS   QASL RGRRTARPSGDDRELAIL TAE LL+DRPLADISVDDLAKGAGISRPT
Sbjct  1    MATSPTGQASLHRGRRTARPSGDDRELAILVTAEKLLKDRPLADISVDDLAKGAGISRPT  60

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVV +AD AL+ L + P D DR+ MWRTGINVFFETFGSHKAV
Sbjct  61   FYFYFPSKEAVLLTLLDRVVTEADTALENLIQAP-DADRDTMWRTGINVFFETFGSHKAV  119

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            TRAGQAARATS EV  LWSTFMQKWI+YTA VI+ ERDRGAAP T+PA ELATALNLMNE
Sbjct  120  TRAGQAARATSAEVRHLWSTFMQKWISYTAEVIETERDRGAAPVTVPALELATALNLMNE  179

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTLFASFA EQP VPEA VLDTLVHIWV+SIYGE  
Sbjct  180  RTLFASFAAEQPCVPEAHVLDTLVHIWVSSIYGEGH  215


>gi|183985374|ref|YP_001853665.1| TetR family transcriptional regulator [Mycobacterium marinum 
M]
 gi|183178700|gb|ACC43810.1| transcriptional regulatory repressor protein (TetR-family) EthR 
[Mycobacterium marinum M]
Length=216

 Score =  343 bits (879),  Expect = 1e-92, Method: Compositional matrix adjust.
 Identities = 169/216 (79%), Positives = 184/216 (86%), Gaps = 1/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            V+TS ASQAS  RGRR+ARPSGD+RELAIL TAE LLEDRP+ DISVDDLAKGAGISRPT
Sbjct  2    VSTSTASQASPSRGRRSARPSGDERELAILNTAEKLLEDRPMVDISVDDLAKGAGISRPT  61

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVN+AD AL  LA+ P D D   MWR GINVFFETFGSH+AV
Sbjct  62   FYFYFPSKEAVLLTLLDRVVNEADAALDNLAQAP-DVDHVTMWRNGINVFFETFGSHRAV  120

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
             + GQ  R+ S EV ELWSTFMQKWIAYTA +I+AER+RGAAP TLPA ELATALNLMNE
Sbjct  121  VQGGQGVRSISAEVRELWSTFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNE  180

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTL ASF  E+PSVPE  V+DTLVHIWV+SIYGE R
Sbjct  181  RTLSASFLAEEPSVPETHVVDTLVHIWVSSIYGEAR  216


>gi|118620041|ref|YP_908373.1| TetR family transcriptional regulator [Mycobacterium ulcerans 
Agy99]
 gi|118572151|gb|ABL06902.1| transcriptional regulatory repressor protein (TetR-family) EthR 
[Mycobacterium ulcerans Agy99]
Length=215

 Score =  342 bits (876),  Expect = 3e-92, Method: Compositional matrix adjust.
 Identities = 167/216 (78%), Positives = 184/216 (86%), Gaps = 1/216 (0%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            ++TS ASQASL RGRR+ARPSGD+RELAIL TAE LLEDRP+ DISVDDLAKGAGISRPT
Sbjct  1    MSTSTASQASLSRGRRSARPSGDERELAILNTAEKLLEDRPMVDISVDDLAKGAGISRPT  60

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYFPSKEAVLLTLLDRVVN+AD AL  LA+ P D D   MWR GINVFFETFGSH+AV
Sbjct  61   FYFYFPSKEAVLLTLLDRVVNEADAALDNLAQAP-DVDHVTMWRNGINVFFETFGSHRAV  119

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
             + GQ  R+ S EV ELWSTFMQKWIAYTA +I+AER+RGAAP TLPA ELATALNLMNE
Sbjct  120  VQGGQGVRSISTEVRELWSTFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNE  179

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTL ASF  E+PSVPE  V+DTLVH+WV+SIYG  R
Sbjct  180  RTLSASFLAEEPSVPETHVVDTLVHVWVSSIYGAAR  215


>gi|15826909|ref|NP_301172.1| transcriptional regulator [Mycobacterium leprae TN]
 gi|221229387|ref|YP_002502803.1| putative transcriptional regulator [Mycobacterium leprae Br4923]
 gi|13092456|emb|CAC29572.1| putative transcriptional regulator [Mycobacterium leprae]
 gi|219932494|emb|CAR70157.1| putative transcriptional regulator [Mycobacterium leprae Br4923]
Length=214

 Score =  308 bits (790),  Expect = 3e-82, Method: Compositional matrix adjust.
 Identities = 156/197 (80%), Positives = 166/197 (85%), Gaps = 2/197 (1%)

Query  20   PSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRV  79
            PSGDDRELAILATAE LLEDRPL +ISVD LAK AGISRPTFYFYF SKEAVLLTLLDRV
Sbjct  20   PSGDDRELAILATAEQLLEDRPLTEISVDYLAKSAGISRPTFYFYFASKEAVLLTLLDRV  79

Query  80   VNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWS  139
             N+A+ AL+TL +N  D  R N WRTGINVFFETFGSHKAVT AGQ  R  + EV +LWS
Sbjct  80   FNKANAALETLIKN-RDNKRGNKWRTGINVFFETFGSHKAVTCAGQVTR-DNTEVRKLWS  137

Query  140  TFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARV  199
            TFMQKWI+YTAAVIDAER RG AP TLPA ELATALNLMNER LFASF  EQP VPE+RV
Sbjct  138  TFMQKWISYTAAVIDAERKRGVAPDTLPATELATALNLMNERALFASFTAEQPHVPESRV  197

Query  200  LDTLVHIWVTSIYGENR  216
            LDTLVHIWV+SIY E R
Sbjct  198  LDTLVHIWVSSIYNEIR  214


>gi|254821452|ref|ZP_05226453.1| transcriptional regulatory repressor protein [Mycobacterium intracellulare 
ATCC 13950]
Length=212

 Score =  280 bits (716),  Expect = 1e-73, Method: Compositional matrix adjust.
 Identities = 134/202 (67%), Positives = 166/202 (83%), Gaps = 2/202 (0%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGRR+ARPSGDDRELAIL TAE LL++RPLADISVDDLAKGAG+SRPTFYFYFPSK+AVL
Sbjct  11   RGRRSARPSGDDRELAILTTAERLLQERPLADISVDDLAKGAGLSRPTFYFYFPSKDAVL  70

Query  73   LTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
             TL +RV+ +AD AL++L  +P   D + +WR GINVF ETFG+H+AV+ A  AAR T+ 
Sbjct  71   FTLFERVIMEADSALESLVASPP-ADLKALWRIGINVFVETFGTHRAVSLAADAAR-TNK  128

Query  133  EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQP  192
            +V ELWS FMQKW+ +   VI+AER RGAAP TLPA  L+ ALNL+NE+ + ++FAG +P
Sbjct  129  DVGELWSRFMQKWVDHITTVIEAERARGAAPVTLPARNLSAALNLLNEKVMLSAFAGGRP  188

Query  193  SVPEARVLDTLVHIWVTSIYGE  214
            SVP  ++LDTLVHIWV+S+YGE
Sbjct  189  SVPSEQLLDTLVHIWVSSVYGE  210


>gi|108802021|ref|YP_642218.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
 gi|108772440|gb|ABG11162.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
Length=221

 Score =  279 bits (714),  Expect = 2e-73, Method: Compositional matrix adjust.
 Identities = 142/216 (66%), Positives = 171/216 (80%), Gaps = 7/216 (3%)

Query  1    VTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPT  60
            VTT  ASQA  PRGRR+ARPSGDDRE AILATAE LLE RP A+ISVDDLAKGAGISRPT
Sbjct  13   VTT--ASQARAPRGRRSARPSGDDREQAILATAEQLLEARPFAEISVDDLAKGAGISRPT  70

Query  61   FYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAV  120
            FYFYF SKEAVLLTL +RV+ +AD AL+  A N      E++WR GI VFF+TFG+H+ V
Sbjct  71   FYFYFGSKEAVLLTLWERVIREADAALENAASNATS---EDVWRPGIKVFFDTFGAHRGV  127

Query  121  TRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE  180
            T A  A+ + + EV ++++ FMQKWI +TAA I+AER RGAAP+TLPA ++ATALNLMNE
Sbjct  128  TVA--ASGSDNAEVRDVFARFMQKWIDFTAATIEAERRRGAAPQTLPARDIATALNLMNE  185

Query  181  RTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            RTL A+FA E P +P  RVLD+LVH+W  ++YGE R
Sbjct  186  RTLLAAFAAETPGIPPDRVLDSLVHVWTCAVYGECR  221


>gi|119871173|ref|YP_941125.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
 gi|119697262|gb|ABL94335.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
Length=209

 Score =  278 bits (711),  Expect = 4e-73, Method: Compositional matrix adjust.
 Identities = 139/213 (66%), Positives = 169/213 (80%), Gaps = 5/213 (2%)

Query  4    SAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYF  63
            + ASQA  PRGRR+ARPSGDDRE AILATAE LLE RP A+ISVDDLAKGAGISRPTFYF
Sbjct  2    TTASQARAPRGRRSARPSGDDREQAILATAEQLLEARPFAEISVDDLAKGAGISRPTFYF  61

Query  64   YFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRA  123
            YF SKEAVLLTL +RV+ +AD AL+  A N      E++WR GI VFF+TFG+H+ VT A
Sbjct  62   YFGSKEAVLLTLWERVIREADAALENAASNATS---EDVWRPGIKVFFDTFGAHRGVTVA  118

Query  124  GQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTL  183
              A+ + + EV ++++ FMQKWI +TAA I+AER RGAAP+TLPA ++ATALNLMNERTL
Sbjct  119  --ASGSDNAEVRDVFARFMQKWIDFTAATIEAERRRGAAPQTLPARDIATALNLMNERTL  176

Query  184  FASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
             A+FA E P +P  RVLD+LVH+W  ++YGE R
Sbjct  177  LAAFAAETPGIPPDRVLDSLVHVWTCAVYGECR  209


>gi|126438000|ref|YP_001073691.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
 gi|126237800|gb|ABO01201.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=209

 Score =  259 bits (661),  Expect = 2e-67, Method: Compositional matrix adjust.
 Identities = 138/213 (65%), Positives = 168/213 (79%), Gaps = 5/213 (2%)

Query  4    SAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYF  63
            + ASQA   RGRR+ARPSGDDRE AILATAE LLE RP A+ISVDDLAKGAGISRPTFYF
Sbjct  2    TTASQARASRGRRSARPSGDDREQAILATAEQLLEARPFAEISVDDLAKGAGISRPTFYF  61

Query  64   YFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRA  123
            YF SKEAVLLTL +RV+ +AD AL+  A N      E++WR GI VFF+TFG+H+ VT A
Sbjct  62   YFGSKEAVLLTLWERVIREADAALENAASNATS---EDVWRPGIKVFFDTFGAHRGVTVA  118

Query  124  GQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTL  183
              A+ + + EV ++++ FMQKWI +TAA I+AER RGAAP+TLPA ++ATALNLMNERTL
Sbjct  119  --ASGSNNAEVRDVFAKFMQKWIDFTAATIEAERRRGAAPQTLPARDIATALNLMNERTL  176

Query  184  FASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
             A+FA E P +P  RVLD+LVH+W  ++YGE R
Sbjct  177  LAAFAAETPGIPPDRVLDSLVHVWTCAVYGECR  209


>gi|120406626|ref|YP_956455.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119959444|gb|ABM16449.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii 
PYR-1]
Length=224

 Score =  258 bits (660),  Expect = 3e-67, Method: Compositional matrix adjust.
 Identities = 129/196 (66%), Positives = 153/196 (79%), Gaps = 3/196 (1%)

Query  21   SGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVV  80
            SGDDRELAIL TAE LL DR LA+ISVDDLAKGAGISRPTFYFYF SK+AVLLTLL+RV+
Sbjct  30   SGDDRELAILETAERLLADRSLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVI  89

Query  81   NQADMAL-QTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWS  139
             +AD AL Q +AE    +DR  +WR GINVFFETFG+H+AV       ++T+ E  ELWS
Sbjct  90   AEADAALAQLIAER--SSDRRTIWRRGINVFFETFGAHRAVCATTVGVKSTNSEARELWS  147

Query  140  TFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARV  199
              MQ+WI + AAVI+AER  GAAP T+PA EL+TALNLMNE  + A+F G QP++P+ RV
Sbjct  148  RSMQRWIDHIAAVIEAERADGAAPVTVPARELSTALNLMNESVMTATFTGHQPAIPDDRV  207

Query  200  LDTLVHIWVTSIYGEN  215
            LD LVHIW TSIYG+ 
Sbjct  208  LDNLVHIWTTSIYGKT  223


>gi|41406277|ref|NP_959113.1| hypothetical protein MAP0179c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41394625|gb|AAS02496.1| hypothetical protein MAP_0179c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=213

 Score =  250 bits (638),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 129/214 (61%), Positives = 156/214 (73%), Gaps = 9/214 (4%)

Query  6    ASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYF  65
            A Q    RGRR  RP+GD+RE AILATAE LLE RP A ISVDDLAKGAG+SRPTFYFYF
Sbjct  4    AGQTRALRGRRAIRPTGDEREQAILATAERLLETRPFAGISVDDLAKGAGLSRPTFYFYF  63

Query  66   PSKEAVLLTLLDRVVNQADM----ALQTLAENPADTDRENMWRTGINVFFETFGSHKAVT  121
             SKEAV+L+LL+ V+ +AD     A+Q L  +P       +WR GI  FF  F SH+A+ 
Sbjct  64   KSKEAVVLSLLEPVIARADAEFDGAVQRLPTDP-----RRVWRNGIKAFFTAFSSHRALA  118

Query  122  RAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNER  181
            RA   A ATS E+  +WS FMQKWI  TAA+I AER+RGAAP T+PA +LAT+LN MNER
Sbjct  119  RAATEALATSSELRAVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNER  178

Query  182  TLFASFAGEQPSVPEARVLDTLVHIWVTSIYGEN  215
            T+ A+ + E P+V E RV+DTL HIWV+SIYGE+
Sbjct  179  TMMAALSAETPAVAEDRVVDTLTHIWVSSIYGES  212


>gi|342860108|ref|ZP_08716760.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
 gi|342132486|gb|EGT85715.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
Length=213

 Score =  249 bits (637),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 127/204 (63%), Positives = 151/204 (75%), Gaps = 3/204 (1%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGRR  RP+GD+RE AILATAE LLE+R LADISVDDLAKGAGISRPTFYFYF SKEAVL
Sbjct  11   RGRRAIRPTGDEREQAILATAERLLEERSLADISVDDLAKGAGISRPTFYFYFKSKEAVL  70

Query  73   LTLLDRVVNQADMALQTLAEN-PADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATS  131
            L+LL+ V+ +AD          PAD  R  +WR GI  FF  F +H+AV R    A ATS
Sbjct  71   LSLLEPVIARADSEFDGAVHRLPADPRR--VWRNGIKAFFTAFSTHRAVARTATEALATS  128

Query  132  VEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQ  191
             E+  LWS +MQKWI  TAA+I AER RGAAP  +PA +LAT+LN MNERT+ A+ + E 
Sbjct  129  TELRSLWSGYMQKWIDQTAAMITAERARGAAPDNIPAADLATSLNQMNERTMMAALSAET  188

Query  192  PSVPEARVLDTLVHIWVTSIYGEN  215
            P+V  ARV+DTL HIW++SIYGE+
Sbjct  189  PAVEAARVVDTLTHIWISSIYGES  212


>gi|254773230|ref|ZP_05214746.1| hypothetical protein MaviaA2_00911 [Mycobacterium avium subsp. 
avium ATCC 25291]
Length=213

 Score =  249 bits (636),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 127/207 (62%), Positives = 154/207 (75%), Gaps = 9/207 (4%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGRR  RP+GD+RE AILATAE LLE RP A ISVDDLAKGAG+SRPTFYFYF SKEAV+
Sbjct  11   RGRRAIRPTGDEREQAILATAERLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVV  70

Query  73   LTLLDRVVNQADM----ALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAAR  128
            L+LL+ V+ +AD     A+Q L  +P       +WR GI  FF  F SH+A+ RA   A 
Sbjct  71   LSLLEPVIARADAEFDGAVQRLPTDP-----RRVWRNGIKAFFTAFSSHRALARAATEAL  125

Query  129  ATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFA  188
            ATS E+  +WS FMQKWI  TAA+I AER+RGAAP T+PA +LAT+LN MNERT+ A+ +
Sbjct  126  ATSSELRSVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALS  185

Query  189  GEQPSVPEARVLDTLVHIWVTSIYGEN  215
             E P+V E RV+DTL HIWV+SIYGE+
Sbjct  186  AETPAVAEDRVVDTLTHIWVSSIYGES  212


>gi|118462741|ref|YP_879467.1| TetR family transcriptional regulator [Mycobacterium avium 104]
 gi|118164028|gb|ABK64925.1| transcriptional regulator, TetR family protein [Mycobacterium 
avium 104]
Length=213

 Score =  247 bits (631),  Expect = 8e-64, Method: Compositional matrix adjust.
 Identities = 128/216 (60%), Positives = 156/216 (73%), Gaps = 9/216 (4%)

Query  4    SAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYF  63
            + A Q    RGRR  RP+GD+RE AILATA  LLE RP A ISVDDLAKGAG+SRPTFYF
Sbjct  2    TTAGQTRALRGRRAIRPTGDEREQAILATALRLLETRPFAGISVDDLAKGAGLSRPTFYF  61

Query  64   YFPSKEAVLLTLLDRVVNQADM----ALQTLAENPADTDRENMWRTGINVFFETFGSHKA  119
            YF SKEAV+L+LL+ V+ +AD     A+Q L  +P       +WR GI  FF  F SH+A
Sbjct  62   YFKSKEAVVLSLLEPVIARADAEFDGAVQRLPTDP-----RRVWRNGIKAFFTAFSSHRA  116

Query  120  VTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMN  179
            + RA   A ATS E+  +WS FMQKWI  TAA+I AER+RGAAP T+PA +LAT+LN MN
Sbjct  117  LARAATEALATSSELRSVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMN  176

Query  180  ERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGEN  215
            ERT+ A+ + E P+V E RV+DTL HIWV+SIYGE+
Sbjct  177  ERTMMAALSAETPAVAEDRVVDTLTHIWVSSIYGES  212


>gi|336461862|gb|EGO40717.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=213

 Score =  247 bits (631),  Expect = 8e-64, Method: Compositional matrix adjust.
 Identities = 128/214 (60%), Positives = 155/214 (73%), Gaps = 9/214 (4%)

Query  6    ASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYF  65
            A Q    RGRR  RP+GD+RE AILATA  LLE RP A ISVDDLAKGAG+SRPTFYFYF
Sbjct  4    AGQTRALRGRRAIRPTGDEREQAILATAGRLLETRPFAGISVDDLAKGAGLSRPTFYFYF  63

Query  66   PSKEAVLLTLLDRVVNQADM----ALQTLAENPADTDRENMWRTGINVFFETFGSHKAVT  121
             SKEAV+L+LL+ V+ +AD     A+Q L  +P       +WR GI  FF  F SH+A+ 
Sbjct  64   KSKEAVVLSLLEPVIARADAEFDGAVQRLPTDP-----RRVWRNGIKAFFTAFSSHRALA  118

Query  122  RAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNER  181
            RA   A ATS E+  +WS FMQKWI  TAA+I AER+RGAAP T+PA +LAT+LN MNER
Sbjct  119  RAATEALATSSELRAVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNER  178

Query  182  TLFASFAGEQPSVPEARVLDTLVHIWVTSIYGEN  215
            T+ A+ + E P+V E RV+DTL HIWV+SIYGE+
Sbjct  179  TMMAALSAETPAVAEDRVVDTLTHIWVSSIYGES  212


>gi|118468283|ref|YP_890654.1| TetR family transcriptional regulator [Mycobacterium smegmatis 
str. MC2 155]
 gi|306755740|sp|A0R666.1|ETHR_MYCS2 RecName: Full=HTH-type transcriptional regulator EthR
 gi|118169570|gb|ABK70466.1| transcriptional regulator, TetR family protein [Mycobacterium 
smegmatis str. MC2 155]
Length=217

 Score =  246 bits (627),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 132/211 (63%), Positives = 156/211 (74%), Gaps = 3/211 (1%)

Query  4    SAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYF  63
            + ASQ   PRGRR+ARPSGDDRE AILATA+ LLE +  A+ISVDDLAKGAGISRPTFYF
Sbjct  2    TTASQTRTPRGRRSARPSGDDREAAILATAQRLLETKKFAEISVDDLAKGAGISRPTFYF  61

Query  64   YFPSKEAVLLTLLDRVVNQADMALQTLAEN-PADTDRENMWRTGINVFFETFGSHKAVTR  122
            YFPSKEAVLL+L+D ++ +AD       E+ PAD  R    R GI +FF +FGSH A  R
Sbjct  62   YFPSKEAVLLSLIDPLIKRADSGFDNAVESMPADPQR--AIRRGIEIFFNSFGSHPATAR  119

Query  123  AGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERT  182
            AG  A  +S E  E WS  MQKWIA TAA+I AER+RGAAP T+PA +LAT+LNLMNERT
Sbjct  120  AGTEALKSSPEFKEFWSGLMQKWIAATAALITAERERGAAPDTIPALDLATSLNLMNERT  179

Query  183  LFASFAGEQPSVPEARVLDTLVHIWVTSIYG  213
            + A+ A EQP V   +V+ TL HIW+ SIYG
Sbjct  180  MMAALADEQPGVAPEKVVATLTHIWLNSIYG  210


>gi|296166985|ref|ZP_06849399.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295897665|gb|EFG77257.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=213

 Score =  246 bits (627),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 128/217 (59%), Positives = 155/217 (72%), Gaps = 9/217 (4%)

Query  4    SAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYF  63
            + A Q    RGRR  RPSGDDRE AILATAE LLE R  ADISVDDLA+GAG+SRPTFYF
Sbjct  2    TTAGQTRALRGRRAIRPSGDDREQAILATAERLLEQRSFADISVDDLARGAGLSRPTFYF  61

Query  64   YFPSKEAVLLTLLDRVVNQADM----ALQTLAENPADTDRENMWRTGINVFFETFGSHKA  119
            YF SK+AVLL+LL+ V+ +AD     A+Q L  +P       +WR GI  FF  F +H+ 
Sbjct  62   YFKSKDAVLLSLLEPVIARADSEFDGAVQRLPTDP-----RRVWRNGIKAFFTAFSTHRR  116

Query  120  VTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMN  179
            + RA   A ATS E+  +W  FMQKWI  TAA+I+AER RGAAP T+PA +LAT+LN MN
Sbjct  117  LARAATEALATSSELRAVWLGFMQKWIDQTAALINAERARGAAPETIPAVDLATSLNQMN  176

Query  180  ERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216
            ERT+ A+ + E P+V E RV++TL HIWVTSIYGE R
Sbjct  177  ERTMMAALSAETPAVHEDRVVNTLAHIWVTSIYGEGR  213


>gi|333992812|ref|YP_004525426.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601]
 gi|333488780|gb|AEF38172.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601]
Length=212

 Score =  239 bits (611),  Expect = 2e-61, Method: Compositional matrix adjust.
 Identities = 122/196 (63%), Positives = 146/196 (75%), Gaps = 9/196 (4%)

Query  22   GDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVN  81
            GDDRE AIL TAE LLE RPLA+ISVDDLAKGAGISRPTFYFYF SK+AVLL+LL+ ++ 
Sbjct  19   GDDRERAILTTAERLLEQRPLAEISVDDLAKGAGISRPTFYFYFKSKDAVLLSLLEPLIA  78

Query  82   QADM----ALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAEL  137
             AD     A+Q L  +P       +WR+GI  FF  F SH+A+ RAG  A ATS E   +
Sbjct  79   AADENFVGAVQRLPSDP-----RRIWRSGIKAFFIAFSSHRAIARAGTEALATSPEFKAM  133

Query  138  WSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEA  197
            W+ FMQ+WI  TAA+I AERDRGAAPRT+PA +LAT+LN MNERT+ A+   E+PSV   
Sbjct  134  WNGFMQRWIQQTAAMITAERDRGAAPRTIPALDLATSLNQMNERTMMAALIAEEPSVAHD  193

Query  198  RVLDTLVHIWVTSIYG  213
            RV+DTL HIWV+SIYG
Sbjct  194  RVVDTLTHIWVSSIYG  209


>gi|315446705|ref|YP_004079584.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1]
 gi|315265008|gb|ADU01750.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1]
Length=233

 Score =  231 bits (590),  Expect = 4e-59, Method: Compositional matrix adjust.
 Identities = 121/196 (62%), Positives = 141/196 (72%), Gaps = 3/196 (1%)

Query  20   PSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRV  79
            PSGDDRE AIL TAE LL+ RPL DISVDDLA+GAGISRPTFYFYF SK+AVLL LLDRV
Sbjct  34   PSGDDRESAILTTAERLLDQRPLNDISVDDLARGAGISRPTFYFYFSSKDAVLLALLDRV  93

Query  80   VNQADMALQTLAENPADTDRE--NMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAEL  137
            + +A+           D   E   +W+  I   FETF +H+AV  AG A R ++ EV  +
Sbjct  94   IAEANARADAALGGRDDRPVEPAGVWQ-AIKALFETFAAHRAVMLAGAAMRPSNHEVQRV  152

Query  138  WSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEA  197
            WS FMQKWI YTA  I AER+RGAAP TLPA +LA ALNLMNER + +SFA EQ SVP  
Sbjct  153  WSLFMQKWIDYTAVSISAERERGAAPDTLPAEDLAIALNLMNERIMLSSFASEQASVPAE  212

Query  198  RVLDTLVHIWVTSIYG  213
            R++ TL HIWV+SIYG
Sbjct  213  RLVGTLAHIWVSSIYG  228


>gi|15827524|ref|NP_301787.1| TetR family transcriptional regulator [Mycobacterium leprae TN]
 gi|221230001|ref|YP_002503417.1| putative TetR-family transcriptional regulator [Mycobacterium 
leprae Br4923]
 gi|699124|gb|AAA62890.1| u1756b [Mycobacterium leprae]
 gi|13093074|emb|CAC31451.1| putative TetR-family transcriptional regulator [Mycobacterium 
leprae]
 gi|219933108|emb|CAR71165.1| putative TetR-family transcriptional regulator [Mycobacterium 
leprae Br4923]
Length=217

 Score =  229 bits (585),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 122/202 (61%), Positives = 150/202 (75%), Gaps = 3/202 (1%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGRR+++ SGDDRE AILA AE LL +RPL D SVD+LAKGAGISRPTFYFYFPSK AVL
Sbjct  17   RGRRSSQLSGDDREQAILAVAERLLAERPLGDFSVDELAKGAGISRPTFYFYFPSKNAVL  76

Query  73   LTLLDRVVNQADMALQTLAEN-PADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATS  131
            L+LLD +  ++  A++ LAE  PAD     +WR+ I  FFE  G+H+AV  AG AA+ATS
Sbjct  77   LSLLDDLNMKSRSAVEALAEQLPADP--AAVWRSAITAFFEVCGTHRAVAVAGAAAKATS  134

Query  132  VEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQ  191
             EV  LWST MQ+WI Y  A I AER  G AP T+PA +LA AL LM ER + A+F+ E+
Sbjct  135  PEVRRLWSTVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEK  194

Query  192  PSVPEARVLDTLVHIWVTSIYG  213
            P +P+ +V+DTLVHIW+ SIYG
Sbjct  195  PLIPDKKVIDTLVHIWLASIYG  216


>gi|145221557|ref|YP_001132235.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
 gi|145214043|gb|ABP43447.1| transcriptional regulator, TetR family [Mycobacterium gilvum 
PYR-GCK]
Length=214

 Score =  227 bits (578),  Expect = 9e-58, Method: Compositional matrix adjust.
 Identities = 121/199 (61%), Positives = 141/199 (71%), Gaps = 3/199 (1%)

Query  20   PSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRV  79
            PSGDDRE AIL TAE LLE RPL DISVDDLA+GAGISRPTFYFYF SK+AVLL LLDRV
Sbjct  16   PSGDDRESAILTTAEQLLEQRPLNDISVDDLARGAGISRPTFYFYFSSKDAVLLALLDRV  75

Query  80   VNQADMALQTLAENPADTDRE--NMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAEL  137
            + +A+           D   E   +W+  I   FETF +H+AV  AG A R  + EV  +
Sbjct  76   IAEANARADAALGGRDDRPLEPAGVWQ-AIKALFETFAAHRAVMLAGAAMRPNNPEVQRV  134

Query  138  WSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEA  197
            WS FMQKWI YTAA I AER+RGAAP TLPA +LA ALNLMNER + ++FA EQ +V   
Sbjct  135  WSHFMQKWIDYTAASIRAERERGAAPDTLPAEDLAIALNLMNERIMLSAFASEQAAVTAD  194

Query  198  RVLDTLVHIWVTSIYGENR  216
            R++ TL HIWV+SIYG  R
Sbjct  195  RLVGTLAHIWVSSIYGTPR  213


>gi|296170917|ref|ZP_06852454.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295894466|gb|EFG74210.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=215

 Score =  226 bits (575),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 121/200 (61%), Positives = 150/200 (75%), Gaps = 1/200 (0%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGRR+A  SGDDRE AILATAE LL++RPLAD SVDDLAKGAGISRPTFYFYF SK AVL
Sbjct  15   RGRRSAPHSGDDRERAILATAERLLQERPLADFSVDDLAKGAGISRPTFYFYFRSKNAVL  74

Query  73   LTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
            L+LLD++ ++A  AL+ L    +  D   +WR  I  FFE  GSH AV  AG AA+AT+ 
Sbjct  75   LSLLDQMNSKAQAALRALG-GISSGDPAELWRARIEAFFEVSGSHPAVAVAGAAAKATNP  133

Query  133  EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQP  192
            EV +LWST MQ+WI+ T A I AER RGAAP T+PA +L+ ALN+++ER + A+F  E  
Sbjct  134  EVRQLWSTLMQRWISLTTAAIKAERGRGAAPDTVPAEQLSVALNMLSERVMAATFTAEDE  193

Query  193  SVPEARVLDTLVHIWVTSIY  212
            ++PE R +DTL+HIW+ SIY
Sbjct  194  AMPEDRAVDTLLHIWLASIY  213


>gi|342858547|ref|ZP_08715202.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
 gi|342134251|gb|EGT87431.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
Length=215

 Score =  225 bits (574),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 125/211 (60%), Positives = 154/211 (73%), Gaps = 3/211 (1%)

Query  2    TTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTF  61
            T +   QAS  RGRR +   GDDRE AILATAE LL++RPLAD SVDDLAKGAGISRPTF
Sbjct  6    TQTKYPQAS--RGRRASHYPGDDREQAILATAERLLQERPLADFSVDDLAKGAGISRPTF  63

Query  62   YFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVT  121
            YFYF SK AVLL+LLD++ ++A  AL  L +  +  D E +WR  I  FFE  GSH+AV 
Sbjct  64   YFYFRSKNAVLLSLLDQMNSKAQAALGAL-DVVSSGDPEAIWRARIESFFEVSGSHRAVA  122

Query  122  RAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNER  181
             AG AA+AT+ EV +LWS  M KWI+YT   I AER RGAAP T+PA EL+ ALN+++ER
Sbjct  123  VAGAAAKATNPEVRQLWSALMGKWISYTTIAIKAERGRGAAPDTIPAAELSVALNMLSER  182

Query  182  TLFASFAGEQPSVPEARVLDTLVHIWVTSIY  212
             + A+F  E  ++PE RV+DTL+HIW+ SIY
Sbjct  183  MMAATFTAEDQAIPEDRVIDTLLHIWLASIY  213


>gi|159038126|ref|YP_001537379.1| TetR family transcriptional regulator [Salinispora arenicola 
CNS-205]
 gi|157916961|gb|ABV98388.1| transcriptional regulator, TetR family [Salinispora arenicola 
CNS-205]
Length=223

 Score =  225 bits (574),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 117/213 (55%), Positives = 146/213 (69%), Gaps = 11/213 (5%)

Query  6    ASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYF  65
            ++ A+ PRGRRTAR  GDDRE AIL TAE LL  RP ADIS+DDLA+GAGISRPTFYFYF
Sbjct  3    STAATPPRGRRTARSVGDDRESAILGTAERLLAQRPFADISIDDLARGAGISRPTFYFYF  62

Query  66   PSKEAVLLTLLDRVVNQADM------ALQTLAENPADTDRENMWRTGINVFFETFGSHKA  119
              K+AVLLTLLDRV+ +A+        L  LAE+P     +  WR  I+ F ETFG+H+A
Sbjct  63   SGKDAVLLTLLDRVIEEANANAVAGGVLDRLAEDP-----QTRWRELIHRFHETFGAHRA  117

Query  120  VTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMN  179
            V  A    R T+ EV  LW++ M+ W+  T A I AER RGAAP  LPA  LA ALN MN
Sbjct  118  VVLACAEVRGTNAEVRRLWASVMEHWVQTTEAAIAAERRRGAAPDGLPARALAIALNSMN  177

Query  180  ERTLFASFAGEQPSVPEARVLDTLVHIWVTSIY  212
            ER  +A+FAG+ P++ E  V+D L+ +W+ +IY
Sbjct  178  ERVWYATFAGDGPAIAEQDVVDVLLDVWLAAIY  210


>gi|169628081|ref|YP_001701730.1| TetR family transcriptional regulator [Mycobacterium abscessus 
ATCC 19977]
 gi|169240048|emb|CAM61076.1| Putative transcriptional regulator, TetR family [Mycobacterium 
abscessus]
Length=212

 Score =  223 bits (567),  Expect = 2e-56, Method: Compositional matrix adjust.
 Identities = 107/201 (54%), Positives = 147/201 (74%), Gaps = 1/201 (0%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGR+T RPSGD+R  AILATAE LL  RPLAD+SVDDLA+GAGISRPTFYFYF SKE+VL
Sbjct  7    RGRKTTRPSGDERIQAILATAEELLGKRPLADVSVDDLARGAGISRPTFYFYFSSKESVL  66

Query  73   LTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
            LTL +R++ +AD  + ++ +  A T     WR  I  +F+ FGSH+A+T A  + + TS 
Sbjct  67   LTLAERIIEEADANVASI-DPAAMTSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSP  125

Query  133  EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQP  192
            E+ + WS   + W+A T   I+AER RGAAP  +PA ++A ALNL+N+  + A+F G+QP
Sbjct  126  ELDQRWSEVTENWVANTTVGIEAERARGAAPSVVPARDIAIALNLINQAMMRATFTGQQP  185

Query  193  SVPEARVLDTLVHIWVTSIYG  213
            +V + +V+DTL+H+W+ +IYG
Sbjct  186  AVDDGKVVDTLLHVWLNAIYG  206


>gi|302867732|ref|YP_003836369.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029]
 gi|315505866|ref|YP_004084753.1| regulatory protein TetR [Micromonospora sp. L5]
 gi|302570591|gb|ADL46793.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029]
 gi|315412485|gb|ADU10602.1| regulatory protein TetR [Micromonospora sp. L5]
Length=226

 Score =  221 bits (564),  Expect = 4e-56, Method: Compositional matrix adjust.
 Identities = 116/213 (55%), Positives = 147/213 (70%), Gaps = 2/213 (0%)

Query  1    VTTSAASQASLP-RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRP  59
            +TT+     + P RGRR  R +GDDRE AILATAE LL +RP ADIS+DDLA+GAGISRP
Sbjct  1    MTTARTPTGAAPTRGRRAGRSTGDDRETAILATAERLLAERPFADISIDDLARGAGISRP  60

Query  60   TFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKA  119
            TFYFYFPSK+AVLLTLLDRV  +AD A   + E  A+  R + WR  I  F  TFG H+ 
Sbjct  61   TFYFYFPSKDAVLLTLLDRVTEEADAAAGGVFERLAEDPRAH-WRELIARFHATFGGHRD  119

Query  120  VTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMN  179
            V  A    R T+ EV  LW+  +++W+    A I++ER RGAAP  LPA +LA ALN MN
Sbjct  120  VVLACAQVRGTNAEVRRLWAEVLERWVRAVQAAIESERARGAAPDGLPARDLAIALNSMN  179

Query  180  ERTLFASFAGEQPSVPEARVLDTLVHIWVTSIY  212
            ER  +A+FAG+ P+V E  V+D L+ +W+T+IY
Sbjct  180  ERVWYATFAGDGPAVAERDVVDVLLDVWLTAIY  212


>gi|111026296|ref|YP_708579.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1]
 gi|110825139|gb|ABH00421.1| transcriptional regulator, TetR family [Rhodococcus jostii RHA1]
Length=247

 Score = 96.7 bits (239),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 68/207 (33%), Positives = 98/207 (48%), Gaps = 3/207 (1%)

Query  8    QASLPR-GRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFP  66
              S PR GRR  +  GD RE AIL  A  +L   PL ++S+DDLAK AG+SR +FYFYF 
Sbjct  33   NGSEPRTGRRNLK--GDRREQAILEGAYEILRTEPLRNVSIDDLAKRAGLSRSSFYFYFE  90

Query  67   SKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQA  126
            SK  VL  LL  V      A   + E P     E      ++     +  H  V R    
Sbjct  91   SKWQVLSALLSSVTADVFTASAMIFERPPGISPEAAIEHAVSEVMVVWERHGHVLREVGD  150

Query  127  ARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFAS  186
            A A    +   W   + +++   AA I+ +R  G A    PA  LA AL  M ER L   
Sbjct  151  AAAAEPTLGAQWDKILGRFVDAAAAAIERDRAAGVALDGPPARSLAAALIWMGERNLGLM  210

Query  187  FAGEQPSVPEARVLDTLVHIWVTSIYG  213
                + ++    +++T+  +W+ +++G
Sbjct  211  SMRSENAIRTEDMVETVTTVWLRTVFG  237


>gi|333027676|ref|ZP_08455740.1| putative short chain dehydrogenase [Streptomyces sp. Tu6071]
 gi|332747528|gb|EGJ77969.1| putative short chain dehydrogenase [Streptomyces sp. Tu6071]
Length=204

 Score = 94.7 bits (234),  Expect = 8e-18, Method: Compositional matrix adjust.
 Identities = 72/199 (37%), Positives = 101/199 (51%), Gaps = 8/199 (4%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            R RR A   GD RE AIL T E LL D+    ++V D+A+GAGI+R   YFYF SK+ V+
Sbjct  8    RSRRAAERKGDVRERAILDTCEALLADKGYDAMTVGDIAQGAGITRGALYFYFGSKQEVV  67

Query  73   LTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
              L+ R V    +  ++ A   AD  R  +    +    E +  H  V R       T  
Sbjct  68   TALVARTVEH--LWERSRATAEADEPRRAI-AAAMGRTVELWNEHGLVMRTAIDLSLTVP  124

Query  133  EVAELWSTFMQKWIAYTAAVID-AERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQ  191
            E+ ELW+     +IA   AV++ A    G AP   PA  +A+AL  M ERT + +    +
Sbjct  125  EIGELWNHTADLFIAAITAVLERAGIQAGTAPDQAPA--MASALCWMIERTFYHASQESR  182

Query  192  PSVPEARVLDTLVHIWVTS  210
             ++ EA   +T  HIW+TS
Sbjct  183  ENLQEAS--ETCEHIWLTS  199


>gi|298246923|ref|ZP_06970728.1| transcriptional regulator, TetR family [Ktedonobacter racemifer 
DSM 44963]
 gi|297549582|gb|EFH83448.1| transcriptional regulator, TetR family [Ktedonobacter racemifer 
DSM 44963]
Length=220

 Score = 94.4 bits (233),  Expect = 9e-18, Method: Compositional matrix adjust.
 Identities = 65/202 (33%), Positives = 101/202 (50%), Gaps = 4/202 (1%)

Query  15   RRTARPSGDDREL--AILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            ++T R   + R++  AIL   E LL  +   ++SV D+   A +SR +FYFYF SK  VL
Sbjct  11   QKTFREESEQRDVRKAILDATEQLLAHQRFDELSVADILSSAQVSRASFYFYFESKYVVL  70

Query  73   LTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
              L+ RVVNQA +A     E   ++  + + R G +   + +  H  V RA      +  
Sbjct  71   GELVRRVVNQAQVAAGPWVEEDIESPEQTL-RQGTSQGLQLWIQHAPVLRAIVENWRSDE  129

Query  133  EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRT-LPAHELATALNLMNERTLFASFAGEQ  191
             +A LW   M+ +       I+ +R  G APRT + A  LA+ L  M+ER  + +  G  
Sbjct  130  RLAALWMEMMEGFTQAATHRIERDRATGRAPRTSVDASTLASTLTWMSERIYYLAAIGHP  189

Query  192  PSVPEARVLDTLVHIWVTSIYG  213
                E +V+D L  +W++ IY 
Sbjct  190  AFHDEQQVIDVLTEVWLSVIYN  211


>gi|302556436|ref|ZP_07308778.1| TetR family transcriptional regulator [Streptomyces viridochromogenes 
DSM 40736]
 gi|302474054|gb|EFL37147.1| TetR family transcriptional regulator [Streptomyces viridochromogenes 
DSM 40736]
Length=204

 Score = 90.5 bits (223),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 74/203 (37%), Positives = 97/203 (48%), Gaps = 16/203 (7%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGRRT    GD RE AIL T E LL  +    ++V D+A+GAGI+R   YFYF SK+ V+
Sbjct  8    RGRRTTERKGDVRERAILDTCEALLTHKGYDAMTVGDIAQGAGITRGALYFYFGSKQEVV  67

Query  73   LTLLDRVVNQ----ADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAAR  128
              L+ R V      + +  QT  + P       M RT      E +  H  V R      
Sbjct  68   TALVARTVEHLWERSRVTAQT--DEPRQAIAAAMQRT-----VELWNEHGPVLRTAIDLS  120

Query  129  ATSVEVAELWSTFMQKWIAYTAAVID-AERDRGAAPRTLPAHELATALNLMNERTLFASF  187
             T  E+ ELW      +IA   AV++ A    GAAP    A  +A AL  M ERT + + 
Sbjct  121  LTVPEIGELWMHTADLFIAAITAVLEHAGIQAGAAPDQASA--MARALCWMIERTFYHAS  178

Query  188  AGEQPSVPEARVLDTLVHIWVTS  210
               +  + EA    T  HIW+TS
Sbjct  179  QESREKLQEASA--TCEHIWLTS  199


>gi|21218783|ref|NP_624562.1| TetR family transcriptional regulator [Streptomyces coelicolor 
A3(2)]
 gi|289774100|ref|ZP_06533478.1| TetR family transcriptional regulator [Streptomyces lividans 
TK24]
 gi|5763889|emb|CAB53270.1| putative tetR-family transcriptional regulator [Streptomyces 
coelicolor A3(2)]
 gi|289704299|gb|EFD71728.1| TetR family transcriptional regulator [Streptomyces lividans 
TK24]
Length=204

 Score = 89.4 bits (220),  Expect = 3e-16, Method: Compositional matrix adjust.
 Identities = 73/204 (36%), Positives = 95/204 (47%), Gaps = 16/204 (7%)

Query  12   PRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAV  71
            P GRR     GD RE AIL T E LL D+    ++V D+A+GAGI+R   YFYF SK  V
Sbjct  7    PLGRRGIERKGDVRERAILDTCEALLADKGYDAMTVGDIAQGAGITRGALYFYFGSKHEV  66

Query  72   LLTLLDRVVNQ----ADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAA  127
            +  L+ R V      + +  QT  + P       M RT      E +  H  V R     
Sbjct  67   VAALVARTVEHLWERSRVTAQT--DEPRQAIAAAMHRT-----VELWNEHGLVMRTAIDL  119

Query  128  RATSVEVAELWSTFMQKWIAYTAAVID-AERDRGAAPRTLPAHELATALNLMNERTLFAS  186
              T  E+ ELWS     +IA   AV++ A    G AP    A  +A AL  M ERT + +
Sbjct  120  SLTVPEIGELWSHTADLFIAAITAVLERAGIQSGTAPEQASA--MARALCWMIERTFYHA  177

Query  187  FAGEQPSVPEARVLDTLVHIWVTS  210
                +  + EA    T  HIW+ S
Sbjct  178  SQESREKLQEASA--TCEHIWLVS  199


>gi|118462781|ref|YP_884182.1| TetR family transcriptional regulator [Mycobacterium avium 104]
 gi|118164068|gb|ABK64965.1| transcriptional regulator, TetR family protein, putative [Mycobacterium 
avium 104]
Length=192

 Score = 88.6 bits (218),  Expect = 6e-16, Method: Compositional matrix adjust.
 Identities = 59/187 (32%), Positives = 90/187 (49%), Gaps = 1/187 (0%)

Query  28   AILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMAL  87
            ++ A    LLE RP  DISV D+ + AG+SR TFYFYF SK +VL  LL++ +      +
Sbjct  6    SLFAATLTLLESRPFTDISVADILEVAGVSRATFYFYFSSKFSVLSGLLEQAMGDIFSTV  65

Query  88   QTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIA  147
            Q       D   +      +      +  H+AV RA          +  LW   ++K+++
Sbjct  66   QPFLSRSDDASPQEALERSLRAVTAAWHRHRAVLRAAAHHWHVDAGLHALWLQIVEKFVS  125

Query  148  YTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVP-EARVLDTLVHI  206
              A  I+ +R  G    T  A  LA+AL    ER L+ +  G +PS+  E   L  L+ +
Sbjct  126  AGAEEIERQRAAGLIKSTESARTLASALFWGTERVLYIAGLGVEPSLSDEEAALGPLLAM  185

Query  207  WVTSIYG  213
            W  ++YG
Sbjct  186  WRGTLYG  192


>gi|316305584|gb|ADU56258.1| putative tetR-family transcriptional regulator [Streptomyces 
kanamyceticus]
Length=204

 Score = 88.2 bits (217),  Expect = 7e-16, Method: Compositional matrix adjust.
 Identities = 71/201 (36%), Positives = 96/201 (48%), Gaps = 12/201 (5%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            R RR+A   GD RE AIL T E LL  +    ++V D+A+GAGI+R   YFYF SK+ V+
Sbjct  8    RSRRSAERKGDLRERAILDTCEALLAHKGYNAMTVGDIAQGAGITRGALYFYFGSKQEVV  67

Query  73   LTLLDRVVNQADMALQTLAEN--PADTDRENMWRTGINVFFETFGSHKAVTRAGQAARAT  130
            + L+ R V       +T A+   P     E M RT      E +  H  V R       T
Sbjct  68   VALVARTVEHLWERSRTTAQTDEPRQAIAEAMQRT-----VELWNEHGLVMRTAIDLSLT  122

Query  131  SVEVAELWSTFMQKWIAYTAAVID-AERDRGAAPRTLPAHELATALNLMNERTLFASFAG  189
              E+ ELWS     +I    AV++ A    G  P    A  +A AL  M ERT + +   
Sbjct  123  VPEIGELWSHTADLFITAITAVLERAGIQSGTEPEQASA--MARALCWMIERTFYHASQE  180

Query  190  EQPSVPEARVLDTLVHIWVTS  210
             + ++  A    T  HIW+TS
Sbjct  181  SRETLQGASA--TCEHIWLTS  199


>gi|319951456|ref|ZP_08025266.1| TetR family transcriptional regulator [Dietzia cinnamea P4]
 gi|319434893|gb|EFV90203.1| TetR family transcriptional regulator [Dietzia cinnamea P4]
Length=217

 Score = 88.2 bits (217),  Expect = 8e-16, Method: Compositional matrix adjust.
 Identities = 68/198 (35%), Positives = 95/198 (48%), Gaps = 12/198 (6%)

Query  20   PSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRV  79
            P GD R  A+LA  ++ L+   L DISV DL + AGI+R  FYFYF SK A +  LL  V
Sbjct  12   PRGDRRREALLAALDDRLKTTALDDISVADLTESAGITRSAFYFYFDSKAAAVGVLLAMV  71

Query  80   VNQADMALQTLAENPADTDRENMWRTGINVFFETFGSH---KA-VTRAGQAARATSVEVA  135
             ++AD A++T      D      +RT +    E        KA + RA   AR+   +  
Sbjct  72   QDEADAAVETAVRGEGD------FRTRVTAALERLTDRVLDKAHIYRALLTARSKHAQTR  125

Query  136  ELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVP  195
            +LW    +      A  + AER  G AP  + A  LA  L  +NE T+    A + P  P
Sbjct  126  DLWDDGRRALAVQIAEFLRAERAAGRAPEGVDADALAVGLIHINE-TVLEQLAYD-PGRP  183

Query  196  EARVLDTLVHIWVTSIYG  213
               +L     +WV ++YG
Sbjct  184  REPLLTVAADMWVRTVYG  201


>gi|325673017|ref|ZP_08152711.1| transcriptional regulator [Rhodococcus equi ATCC 33707]
 gi|325556270|gb|EGD25938.1| transcriptional regulator [Rhodococcus equi ATCC 33707]
Length=229

 Score = 85.5 bits (210),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 71/205 (35%), Positives = 104/205 (51%), Gaps = 15/205 (7%)

Query  16   RTARPS-GDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLT  74
            RT R + G++R  AIL   E LLEDR L +I++ D+++ AG++R  FYFYF +K   +  
Sbjct  30   RTRRANKGEERRAAILDAVERLLEDRTLDEINISDISRAAGVTRSGFYFYFDNKAKAVAA  89

Query  75   LLDRVVNQ-ADMALQTLAENPADTDRENMWRTGIN-VFFETFGS---HKAVTRAGQAARA  129
            L   V  +  + A   LA       RE   R  I+ +  E  G+   H  + RA + AR 
Sbjct  90   LSRTVYGEMQEGARGYLA-------REGSPREMIDGLITEVIGTWERHPNLYRALRDARD  142

Query  130  TSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFA-SFA  188
            +   V E+W      ++   A+VIDAER  G A     +  LA  L  MN+R + + S  
Sbjct  143  SDPTVREMWDHDRFSFVDPVASVIDAERTSGRAADGPDSRALAVVLLDMNDRAVESLSRG  202

Query  189  GEQPSVPEARVLDTLVHIWVTSIYG  213
            G +   PE    + LV +W+ SIYG
Sbjct  203  GPEALTPET-AREALVAVWLNSIYG  226


>gi|312141723|ref|YP_004009059.1| tetr family transcriptional regulator [Rhodococcus equi 103S]
 gi|311891062|emb|CBH50381.1| putative TetR family transcriptional regulator [Rhodococcus equi 
103S]
Length=211

 Score = 85.5 bits (210),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 71/205 (35%), Positives = 104/205 (51%), Gaps = 15/205 (7%)

Query  16   RTARPS-GDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLT  74
            RT R + G++R  AIL   E LLEDR L +I++ D+++ AG++R  FYFYF +K   +  
Sbjct  12   RTRRANKGEERRAAILDAVERLLEDRTLDEINISDISRAAGVTRSGFYFYFDNKAKAVAA  71

Query  75   LLDRVVNQ-ADMALQTLAENPADTDRENMWRTGIN-VFFETFGS---HKAVTRAGQAARA  129
            L   V  +  + A   LA       RE   R  I+ +  E  G+   H  + RA + AR 
Sbjct  72   LSRTVYGEMQEGARGYLA-------REGSPREMIDGLITEVIGTWERHPNLYRALRDARD  124

Query  130  TSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFA-SFA  188
            +   V E+W      ++   A+VIDAER  G A     +  LA  L  MN+R + + S  
Sbjct  125  SDPTVREMWDHDRFSFVDPVASVIDAERTSGRAADGPDSRALAVVLLDMNDRAVESLSRG  184

Query  189  GEQPSVPEARVLDTLVHIWVTSIYG  213
            G +   PE    + LV +W+ SIYG
Sbjct  185  GPEALTPET-AREALVAVWLNSIYG  208


>gi|320012916|gb|ADW07766.1| regulatory protein TetR [Streptomyces flavogriseus ATCC 33331]
Length=205

 Score = 85.1 bits (209),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 67/198 (34%), Positives = 96/198 (49%), Gaps = 6/198 (3%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGRRT    GD RE AIL T E LL  +    ++V D+A+GAGI+R   YFYF SK+ V+
Sbjct  9    RGRRTTGRKGDVRERAILDTCEALLAHKGYDAMTVGDVAQGAGITRGALYFYFGSKQEVV  68

Query  73   LTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
              L+ R V    +  ++ A    D  R+ +    +    E +  H  V R       T  
Sbjct  69   TALVARTVEH--LWERSRATAQTDEPRQAI-AAAMQRTVELWNEHGLVMRTAIDLSLTVP  125

Query  133  EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQP  192
            E+ ELW      +IA   AV++    + A  R   A  +A AL  M ERT + +    + 
Sbjct  126  EIGELWKHTADLFIAAITAVLERAGIQ-AGTRPDQASAMARALCWMIERTFYHASQESRE  184

Query  193  SVPEARVLDTLVHIWVTS  210
            ++ EA   +T  HIW+ S
Sbjct  185  NLQEAS--ETCEHIWLIS  200


>gi|256397954|ref|YP_003119518.1| TetR family transcriptional regulator [Catenulispora acidiphila 
DSM 44928]
 gi|256364180|gb|ACU77677.1| transcriptional regulator, TetR family [Catenulispora acidiphila 
DSM 44928]
Length=202

 Score = 84.7 bits (208),  Expect = 8e-15, Method: Compositional matrix adjust.
 Identities = 68/201 (34%), Positives = 95/201 (48%), Gaps = 16/201 (7%)

Query  15   RRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLT  74
            RR A+  GD RE AIL T E LL D+    ++V D+A+GAGI+R   YFYF SK+ V+  
Sbjct  9    RRAAQSKGDLRERAILDTCEALLTDKGYDAVTVGDIAQGAGITRGALYFYFGSKQEVVTA  68

Query  75   LLDRVVNQADMALQTLAENPADTDRENMWR----TGINVFFETFGSHKAVTRAGQAARAT  130
            L+ R V         L E    T R ++ R    T +    E +  H  V R       T
Sbjct  69   LVARTVEH-------LWERSRSTARADVPRQAIATAMRRTVELWNEHGPVMRTAIDLSLT  121

Query  131  SVEVAELWSTFMQKWIAYTAAVID-AERDRGAAPRTLPAHELATALNLMNERTLFASFAG  189
              E+  LW+     +I   AAV++ A  + G  P+   A  +A AL  M ER  + +   
Sbjct  122  VPEIGNLWNQTADLFIEAIAAVLEHAGVEPGDEPKQASA--MARALCWMIERNFYHASQE  179

Query  190  EQPSVPEARVLDTLVHIWVTS  210
             + S+      DT  HIW+ S
Sbjct  180  SRESLQNTS--DTCEHIWLIS  198


>gi|320012886|gb|ADW07736.1| regulatory protein TetR [Streptomyces flavogriseus ATCC 33331]
Length=204

 Score = 84.3 bits (207),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 66/198 (34%), Positives = 96/198 (49%), Gaps = 6/198 (3%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            RGRRT    GD RE AIL T E LL  +    ++V D+A+GAGI+R   YFYF SK+ V+
Sbjct  8    RGRRTTERKGDVRERAILDTCEALLAHKGYDAMTVGDVAQGAGITRGALYFYFGSKQEVV  67

Query  73   LTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
              L+ R V    +  ++ A    D  R+ +    +    E +  H  V R       T  
Sbjct  68   TALVARTVEH--LWERSRATAQTDEPRQAI-AAAMQRTVELWNEHGLVMRTAIDLSLTVP  124

Query  133  EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQP  192
            E+ ELW      +IA   AV++    + A  R   A  +A AL  M ERT + +    + 
Sbjct  125  EIGELWKHTADLFIAAITAVLERAGIQ-AGTRPDQASAMARALCWMIERTFYHASQESRE  183

Query  193  SVPEARVLDTLVHIWVTS  210
            ++ +A   +T  HIW+ S
Sbjct  184  NLQKAS--ETCEHIWLIS  199


>gi|294649677|ref|ZP_06727088.1| transcriptional regulator [Acinetobacter haemolyticus ATCC 19194]
 gi|292824431|gb|EFF83223.1| transcriptional regulator [Acinetobacter haemolyticus ATCC 19194]
Length=212

 Score = 84.3 bits (207),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 60/199 (31%), Positives = 94/199 (48%), Gaps = 8/199 (4%)

Query  19   RPSGDDRE--LAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLL  76
            RP  D +E    IL  AE  L +RP  +++VD++ K  G+ RP FY +F  K  + L ++
Sbjct  15   RPKHDPKESEREILNAAEKFLSERPFRELNVDEVMKLTGLKRPAFYVHFSDKYDLALCVV  74

Query  77   DRVVNQA-DMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVA  135
              +  +   +A + L  N    D        +NV    +  H AV RA   A      V 
Sbjct  75   QDIGQELFRLANRWLKGNNFPEDSLQALEGIVNV----YQKHGAVLRAIAEASVADARVE  130

Query  136  ELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVP  195
            +++ T +Q +I  T   I  E+  G   + L   E A AL  + ER L  +F G  P   
Sbjct  131  QIYRTLIQDFIDATIKHIHEEQASGRIQKKLNVEETARALIWLEERYLVEAF-GRLPHTD  189

Query  196  EARVLDTLVHIWVTSIYGE  214
               V++ L +IW++++YGE
Sbjct  190  PKIVVNVLQNIWISTLYGE  208


>gi|50085844|ref|YP_047354.1| transcriptional regulator [Acinetobacter sp. ADP1]
 gi|49531820|emb|CAG69532.1| putative transcriptional regulator (TetR family) [Acinetobacter 
sp. ADP1]
Length=201

 Score = 83.2 bits (204),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 59/205 (29%), Positives = 101/205 (50%), Gaps = 12/205 (5%)

Query  15   RRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLT  74
            RR  +    + E  IL  A+  L +RP  +++VD++ +  G+ RP FY +F  K  + L 
Sbjct  5    RRRPKHDPKESEQEILNAAKQFLNERPFRELTVDEVMRRTGLKRPAFYVHFRDKHDLALR  64

Query  75   LLDRVVNQ----ADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARAT  130
            L+  +  +    AD  L+   +NP    +E++ R  + +  E +  H  V RA   A + 
Sbjct  65   LVQAIGQELFGIADRWLE--GDNP----QEDLRRALVGL-VEVYMKHSHVLRAFAEAASG  117

Query  131  SVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGE  190
               V  ++  F+Q++I+  A  I  E+  G   + +   E A AL  + ER L   F   
Sbjct  118  DERVNSIYRAFVQEFISAAAQHIREEQATGQIQKDIDIDETARALIWLEERYLSDVFGRM  177

Query  191  QPSVPEARVLDTLVHIWVTSIYGEN  215
             P+ PE  V+  L +IW++++YG N
Sbjct  178  PPADPEV-VIRVLQNIWISTLYGSN  201


>gi|302546925|ref|ZP_07299267.1| TetR-family transcriptional regulator [Streptomyces hygroscopicus 
ATCC 53653]
 gi|302464543|gb|EFL27636.1| TetR-family transcriptional regulator [Streptomyces himastatinicus 
ATCC 53653]
Length=204

 Score = 82.4 bits (202),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 66/200 (33%), Positives = 93/200 (47%), Gaps = 10/200 (5%)

Query  13   RGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVL  72
            R RRT    GD RE  IL T E LL  +    ++V D+A+GAGI+R   YFYF SK+ V+
Sbjct  8    RSRRTTERKGDVRERVILDTCEALLARKGYDAMTVGDIAQGAGITRGALYFYFGSKQEVV  67

Query  73   LTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
              L+ R V    +  ++ A   AD  R+ +    +    E +  H  V R       +  
Sbjct  68   TALVARTVEH--LWERSRATAQADEPRQAI-AAAMRRTVELWNEHGLVMRTAIDLSLSVP  124

Query  133  EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLP--AHELATALNLMNERTLFASFAGE  190
            E+ ELWS     +I    AV++     G  P T P  A  +A AL  M ERT +   A +
Sbjct  125  EIGELWSRTADLFITAITAVLERA---GVQPGTEPDQASAMARALCWMIERTFY--HASQ  179

Query  191  QPSVPEARVLDTLVHIWVTS  210
            +      +   T  HIW+ S
Sbjct  180  ESREKLQKASSTCEHIWLVS  199


>gi|163840689|ref|YP_001625094.1| TetR family transcriptional regulator [Renibacterium salmoninarum 
ATCC 33209]
 gi|162954165|gb|ABY23680.1| transcriptional regulator, TetR family [Renibacterium salmoninarum 
ATCC 33209]
Length=204

 Score = 82.4 bits (202),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 66/198 (34%), Positives = 91/198 (46%), Gaps = 16/198 (8%)

Query  15   RRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLT  74
            RR A   GD RE  IL T E LL ++    ++V D+A+GA +SR   YFYF SK+  +  
Sbjct  10   RRPAERKGDIRERTILDTCEALLAEKGYEAMTVGDIAQGAELSRAAMYFYFGSKQETVTA  69

Query  75   LLDRVVNQ--ADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSV  132
            L+ R V Q      + +  EN A+     M RT      E +  H  V R       T  
Sbjct  70   LVARTVEQLWERSRVTSETENSAEAIAMAMQRT-----VELWSKHGLVMRTAIDLSHTVP  124

Query  133  EVAELWSTFMQKWIAYTAAVIDAERDRGAAP---RTLPAHELATALNLMNERTLFASFAG  189
            E+ ELW+     +IA   +V+    +R   P   +T  A  +A AL  M ERTL+ +  G
Sbjct  125  EIGELWNRTADLFIAAITSVL----ERAGVPAGGKTTQATAMAQALCWMIERTLYHASQG  180

Query  190  EQPSVPEARVLDTLVHIW  207
                +  A    T  HIW
Sbjct  181  TLAELQSAS--STCAHIW  196



Lambda     K      H
   0.318    0.129    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 260686263632


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40