BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv3875
Length=95
Score E
Sequences producing significant alignments: (Bits) Value
gi|15843506|ref|NP_338543.1| early secretory antigenic target, 6... 187 4e-46
gi|189086691|gb|ACD75763.1| immunodominant chimeric antigen Ag85... 186 1e-45
gi|269914409|pdb|3FAV|B Chain B, Structure Of The Cfp10-Esat6 Co... 185 2e-45
gi|71041815|pdb|1WA8|B Chain B, Solution Structure Of The Cfp-10... 185 2e-45
gi|240168354|ref|ZP_04747013.1| 6 kDa early secretory antigenic ... 184 5e-45
gi|289445477|ref|ZP_06435221.1| 6 kDa early secretory antigenic ... 182 1e-44
gi|196166620|gb|ACG70854.1| 6 kDa early secretory antigenic targ... 182 2e-44
gi|190495983|gb|ACB41410.2| Esat6 [Mycobacterium riyadhense] 182 2e-44
gi|183985421|ref|YP_001853712.1| 6 kDa early secretory antigenic... 175 2e-42
gi|166092933|gb|ABY82426.1| 6 kDa early secreted antigenic prote... 172 1e-41
gi|194318358|gb|ACF47573.1| 6 kDa early secretory antigenic targ... 171 4e-41
gi|183980222|ref|YP_001848513.1| 6 kDa culture filtrate antigen ... 169 1e-40
gi|194318356|gb|ACF47572.1| 6 kDa early secretory antigenic targ... 161 3e-38
gi|3253157|gb|AAC83446.1| early secreted antigenic target 6 kDa ... 139 1e-31
gi|118473376|ref|YP_884484.1| early secretory antigenic target, ... 132 1e-29
gi|108797052|ref|YP_637249.1| 6 kDa early secretory antigenic ta... 125 3e-27
gi|60459457|gb|AAX20068.1| small secreted antigenic protein Esat... 122 2e-26
gi|289764065|ref|ZP_06523443.1| LOW QUALITY PROTEIN: early secre... 108 2e-22
gi|58220781|gb|AAW68022.1| ESAT-6 [Mycobacterium ulcerans] >gi|5... 101 3e-20
gi|58220777|gb|AAW68020.1| ESAT-6 [Mycobacterium ulcerans] 100 1e-19
gi|145221361|ref|YP_001132039.1| early secretory antigenic targe... 83.2 1e-14
gi|183980229|ref|YP_001848520.1| EsxA-like protein, EsxA_2 [Myco... 80.9 6e-14
gi|183980223|ref|YP_001848514.1| EsxA-like protein, EsxA_3 [Myco... 80.5 7e-14
gi|221229377|ref|YP_002502793.1| putative secreted protein [Myco... 76.3 1e-12
gi|120401107|ref|YP_950936.1| 6 kDa early secretory antigenic ta... 73.2 1e-11
gi|15826899|ref|NP_301162.1| hypothetical protein ML0049 [Mycoba... 73.2 1e-11
gi|334563185|ref|ZP_08516176.1| hypothetical protein CbovD2_0131... 65.5 2e-09
gi|38233168|ref|NP_938935.1| ESAT-6-like protein [Corynebacteriu... 64.3 6e-09
gi|68536837|ref|YP_251542.1| hypothetical protein jk1747 [Coryne... 63.2 1e-08
gi|305679881|ref|ZP_07402691.1| WXG100 family type VII secretion... 62.4 2e-08
gi|225020500|ref|ZP_03709692.1| hypothetical protein CORMATOL_00... 61.2 5e-08
gi|213964911|ref|ZP_03393110.1| conserved hypothetical protein [... 60.5 9e-08
gi|296394878|ref|YP_003659762.1| hypothetical protein Srot_2494 ... 59.7 1e-07
gi|227541777|ref|ZP_03971826.1| ESAT-6 family protein [Corynebac... 58.5 4e-07
gi|256380551|ref|YP_003104211.1| hypothetical protein Amir_6566 ... 58.2 4e-07
gi|296119294|ref|ZP_06837862.1| early secretory antigenic target... 57.8 5e-07
gi|19551814|ref|NP_599816.1| hypothetical protein NCgl0555 [Cory... 57.4 7e-07
gi|25027139|ref|NP_737193.1| hypothetical protein CE0583 [Coryne... 57.0 8e-07
gi|227487060|ref|ZP_03917376.1| ESAT-6 family protein [Corynebac... 56.2 2e-06
gi|300857819|ref|YP_003782802.1| hypothetical protein cpfrc_0040... 56.2 2e-06
gi|227502708|ref|ZP_03932757.1| ESAT-6 family protein [Corynebac... 55.1 4e-06
gi|337290070|ref|YP_004629091.1| hypothetical protein CULC22_004... 54.7 5e-06
gi|229821686|ref|YP_002883212.1| hypothetical protein Bcav_3206 ... 53.9 7e-06
gi|332669470|ref|YP_004452478.1| hypothetical protein Celf_0954 ... 53.9 7e-06
gi|311898690|dbj|BAJ31098.1| hypothetical protein KSE_53230 [Kit... 53.5 1e-05
gi|255324788|ref|ZP_05365902.1| conserved hypothetical protein [... 53.5 1e-05
gi|172040054|ref|YP_001799768.1| hypothetical protein cur_0374 [... 53.5 1e-05
gi|330470640|ref|YP_004408383.1| hypothetical protein VAB18032_0... 52.4 3e-05
gi|227549882|ref|ZP_03979931.1| conserved hypothetical protein [... 52.0 3e-05
gi|169629412|ref|YP_001703061.1| hypothetical protein MAB_2326c ... 52.0 3e-05
>gi|15843506|ref|NP_338543.1| early secretory antigenic target, 6 kDa [Mycobacterium tuberculosis
CDC1551]
gi|31795049|ref|NP_857542.1| 6 kDa early secretory antigenic target EsaT6 (EsaT-6) [Mycobacterium
bovis AF2122/97]
gi|57117165|ref|YP_178023.1| 6 kDa early secretory antigenic target ESXA (ESAT-6) [Mycobacterium
tuberculosis H37Rv]
85 more sequence titles
Length=95
Score = 187 bits (475), Expect = 4e-46, Method: Compositional matrix adjust.
Identities = 95/95 (100%), Positives = 95/95 (100%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA
Sbjct 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TATELNNALQNLARTISEAGQAMASTEGNVTGMFA
Sbjct 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
>gi|189086691|gb|ACD75763.1| immunodominant chimeric antigen Ag856A2 [synthetic construct]
Length=489
Score = 186 bits (471), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 94/95 (99%), Positives = 94/95 (99%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M EQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA
Sbjct 146 MAEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 205
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TATELNNALQNLARTISEAGQAMASTEGNVTGMFA
Sbjct 206 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 240
Score = 186 bits (471), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 94/95 (99%), Positives = 94/95 (99%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M EQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA
Sbjct 243 MAEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 302
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TATELNNALQNLARTISEAGQAMASTEGNVTGMFA
Sbjct 303 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 337
>gi|269914409|pdb|3FAV|B Chain B, Structure Of The Cfp10-Esat6 Complex From Mycobacterium
Tuberculosis
gi|269914411|pdb|3FAV|D Chain D, Structure Of The Cfp10-Esat6 Complex From Mycobacterium
Tuberculosis
Length=94
Score = 185 bits (469), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 94/94 (100%), Positives = 94/94 (100%), Gaps = 0/94 (0%)
Query 2 TEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDAT 61
TEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDAT
Sbjct 1 TEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDAT 60
Query 62 ATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
ATELNNALQNLARTISEAGQAMASTEGNVTGMFA
Sbjct 61 ATELNNALQNLARTISEAGQAMASTEGNVTGMFA 94
>gi|71041815|pdb|1WA8|B Chain B, Solution Structure Of The Cfp-10.Esat-6 Complex. Major
Virulence Determinants Of Pathogenic Mycobacteria
Length=95
Score = 185 bits (469), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 94/94 (100%), Positives = 94/94 (100%), Gaps = 0/94 (0%)
Query 2 TEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDAT 61
TEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDAT
Sbjct 2 TEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDAT 61
Query 62 ATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
ATELNNALQNLARTISEAGQAMASTEGNVTGMFA
Sbjct 62 ATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
>gi|240168354|ref|ZP_04747013.1| 6 kDa early secretory antigenic target esxA (Esat-6) [Mycobacterium
kansasii ATCC 12478]
gi|196166614|gb|ACG70851.1| 6 kDa early secretory antigenic target [Mycobacterium kansasii]
gi|196166616|gb|ACG70852.1| 6 kDa early secretory antigenic target [Mycobacterium kansasii]
gi|196166618|gb|ACG70853.1| 6 kDa early secretory antigenic target [Mycobacterium kansasii]
gi|196166622|gb|ACG70855.1| 6 kDa early secretory antigenic target [Mycobacterium kansasii]
Length=95
Score = 184 bits (466), Expect = 5e-45, Method: Compositional matrix adjust.
Identities = 93/95 (98%), Positives = 94/95 (99%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA
Sbjct 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TA ELNNALQNL+RTISEAGQAMASTEGNVTGMFA
Sbjct 61 TAQELNNALQNLSRTISEAGQAMASTEGNVTGMFA 95
>gi|289445477|ref|ZP_06435221.1| 6 kDa early secretory antigenic target esxA [Mycobacterium tuberculosis
CPHL_A]
gi|289418435|gb|EFD15636.1| 6 kDa early secretory antigenic target esxA [Mycobacterium tuberculosis
CPHL_A]
Length=95
Score = 182 bits (463), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 94/95 (99%), Positives = 94/95 (99%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA
Sbjct 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TATELNNALQNLA TISEAGQAMASTEGNVTGMFA
Sbjct 61 TATELNNALQNLAWTISEAGQAMASTEGNVTGMFA 95
>gi|196166620|gb|ACG70854.1| 6 kDa early secretory antigenic target [Mycobacterium kansasii]
gi|196166624|gb|ACG70856.1| 6 kDa early secretory antigenic target [Mycobacterium kansasii]
Length=95
Score = 182 bits (462), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 92/95 (97%), Positives = 94/95 (99%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA
Sbjct 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TA ELN+ALQNL+RTISEAGQAMASTEGNVTGMFA
Sbjct 61 TAQELNSALQNLSRTISEAGQAMASTEGNVTGMFA 95
>gi|190495983|gb|ACB41410.2| Esat6 [Mycobacterium riyadhense]
Length=95
Score = 182 bits (461), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 92/95 (97%), Positives = 93/95 (98%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAA+SAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA
Sbjct 1 MTEQQWNFAGIEAASSAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TA ELNNALQNLARTISEAGQAM STEGNVTGMFA
Sbjct 61 TAQELNNALQNLARTISEAGQAMQSTEGNVTGMFA 95
>gi|183985421|ref|YP_001853712.1| 6 kDa early secretory antigenic target EsxA (EsaT-6) [Mycobacterium
marinum M]
gi|183178747|gb|ACC43857.1| 6 kDa early secretory antigenic target EsxA (EsaT-6) [Mycobacterium
marinum M]
Length=95
Score = 175 bits (443), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 87/95 (92%), Positives = 92/95 (97%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAA+SAIQGNVTSIHSLLDEGKQSL KLAAAWGGSGSEAY+GVQQ WD+
Sbjct 1 MTEQQWNFAGIEAASSAIQGNVTSIHSLLDEGKQSLHKLAAAWGGSGSEAYRGVQQNWDS 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TA ELNN+LQNLARTISEAGQAM+STEGNVTGMFA
Sbjct 61 TAQELNNSLQNLARTISEAGQAMSSTEGNVTGMFA 95
>gi|166092933|gb|ABY82426.1| 6 kDa early secreted antigenic protein [Mycobacterium ulcerans]
gi|166092935|gb|ABY82427.1| 6 kDa early secreted antigenic protein [Mycobacterium ulcerans]
gi|166092937|gb|ABY82428.1| 6 kDa early secreted antigenic protein [Mycobacterium ulcerans]
gi|166092939|gb|ABY82429.1| 6 kDa early secreted antigenic protein [Mycobacterium ulcerans]
Length=95
Score = 172 bits (437), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 87/95 (92%), Positives = 91/95 (96%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAA+S+I GNV SIHSLLDEGKQSL KLAAAWGGSGSEAYQGVQQKWD+
Sbjct 1 MTEQQWNFAGIEAASSSIGGNVGSIHSLLDEGKQSLHKLAAAWGGSGSEAYQGVQQKWDS 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TA ELNNALQNLARTISEAGQAM+STEGNVTGMFA
Sbjct 61 TAQELNNALQNLARTISEAGQAMSSTEGNVTGMFA 95
>gi|194318358|gb|ACF47573.1| 6 kDa early secretory antigenic target [Mycobacterium marinum]
Length=95
Score = 171 bits (432), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 86/95 (91%), Positives = 90/95 (95%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAA+S+I GNV SIHSLLDEGKQSL KLAAAWGGSGSEAYQGVQQKWD+
Sbjct 1 MTEQQWNFAGIEAASSSIGGNVGSIHSLLDEGKQSLHKLAAAWGGSGSEAYQGVQQKWDS 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TA ELNNALQNLARTISEAGQAM+STEGNV GMFA
Sbjct 61 TAQELNNALQNLARTISEAGQAMSSTEGNVAGMFA 95
>gi|183980222|ref|YP_001848513.1| 6 kDa culture filtrate antigen EsxA_1 (early secreted antigenic
target - Esat6) [Mycobacterium marinum M]
gi|166092941|gb|ABY82430.1| 6 kDa early secreted antigenic protein [Mycobacterium ulcerans]
gi|183173548|gb|ACC38658.1| 6 kDa culture filtrate antigen EsxA_1 (early secreted antigenic
target - Esat6) [Mycobacterium marinum M]
Length=95
Score = 169 bits (428), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 85/94 (91%), Positives = 89/94 (95%), Gaps = 0/94 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAA+S+I GNV SIHSLLDEGKQSL KLAAAWGGSGSEAYQGVQQKWD+
Sbjct 1 MTEQQWNFAGIEAASSSIGGNVGSIHSLLDEGKQSLHKLAAAWGGSGSEAYQGVQQKWDS 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMF 94
TA ELNNALQNLARTISEAGQAM+STEGNV GMF
Sbjct 61 TAQELNNALQNLARTISEAGQAMSSTEGNVAGMF 94
>gi|194318356|gb|ACF47572.1| 6 kDa early secretory antigenic target [Mycobacterium szulgai]
Length=95
Score = 161 bits (407), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 81/95 (86%), Positives = 87/95 (92%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAAAS+IQGNVTSIHSLLDEGKQSLTKL +AW G+G AY+ VQQKWDA
Sbjct 1 MTEQQWNFAGIEAAASSIQGNVTSIHSLLDEGKQSLTKLQSAWAGAGQGAYEQVQQKWDA 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
TA ELN++LQNLARTISEAGQ M STEGNVTGMFA
Sbjct 61 TAQELNSSLQNLARTISEAGQHMQSTEGNVTGMFA 95
>gi|3253157|gb|AAC83446.1| early secreted antigenic target 6 kDa [Mycobacterium tuberculosis
H37Rv]
Length=70
Score = 139 bits (351), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 70/70 (100%), Positives = 70/70 (100%), Gaps = 0/70 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA
Sbjct 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
Query 61 TATELNNALQ 70
TATELNNALQ
Sbjct 61 TATELNNALQ 70
>gi|118473376|ref|YP_884484.1| early secretory antigenic target, 6 kDa [Mycobacterium smegmatis
str. MC2 155]
gi|118174663|gb|ABK75559.1| early secretory antigenic target, 6 kDa [Mycobacterium smegmatis
str. MC2 155]
Length=95
Score = 132 bits (333), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 68/95 (72%), Positives = 76/95 (80%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
MTEQ WNFAGIE AS I G V++ LLDEGK SLT LA+AWGG+GSEAYQ VQ +WD+
Sbjct 1 MTEQVWNFAGIEGGASEIHGAVSTTAGLLDEGKASLTTLASAWGGTGSEAYQAVQARWDS 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
T+ ELN ALQNLA+TISEAGQ MA TE VTGMFA
Sbjct 61 TSNELNLALQNLAQTISEAGQTMAQTEAGVTGMFA 95
>gi|108797052|ref|YP_637249.1| 6 kDa early secretory antigenic target EsaT6 [Mycobacterium sp.
MCS]
gi|119866137|ref|YP_936089.1| 6 kDa early secretory antigenic target EsaT6 [Mycobacterium sp.
KMS]
gi|126432674|ref|YP_001068365.1| 6 kDa early secretory antigenic target EsaT6 [Mycobacterium sp.
JLS]
gi|108767471|gb|ABG06193.1| 6 kDa early secretory antigenic target EsaT6 (EsaT-6) [Mycobacterium
sp. MCS]
gi|119692226|gb|ABL89299.1| 6 kDa early secretory antigenic target EsaT6 (EsaT-6) [Mycobacterium
sp. KMS]
gi|126232474|gb|ABN95874.1| 6 kDa early secretory antigenic target EsaT6 (EsaT-6) [Mycobacterium
sp. JLS]
Length=95
Score = 125 bits (313), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 65/95 (69%), Positives = 71/95 (75%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M+EQ WNFAGIE A I G V++ LLDEGK SL LAA WGGSGSEAYQ VQ +WD
Sbjct 1 MSEQVWNFAGIEGGAGEINGAVSTTQGLLDEGKASLGALAAVWGGSGSEAYQAVQARWDN 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
T+ ELN ALQNLA+TISEAG MA TE VTGMFA
Sbjct 61 TSAELNAALQNLAQTISEAGSTMAQTEAGVTGMFA 95
>gi|60459457|gb|AAX20068.1| small secreted antigenic protein Esat6 [Mycobacterium liflandii]
Length=72
Score = 122 bits (306), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 61/68 (90%), Positives = 64/68 (95%), Gaps = 0/68 (0%)
Query 3 EQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATA 62
EQQWNFAGIEAA+S+I GNV SIHSLLDEGKQSL KLAAAWGGSGSEAYQGVQQKWD+TA
Sbjct 1 EQQWNFAGIEAASSSIGGNVGSIHSLLDEGKQSLHKLAAAWGGSGSEAYQGVQQKWDSTA 60
Query 63 TELNNALQ 70
ELNNALQ
Sbjct 61 QELNNALQ 68
>gi|289764065|ref|ZP_06523443.1| LOW QUALITY PROTEIN: early secretory antigenic target protein
[Mycobacterium tuberculosis GM 1503]
gi|289711571|gb|EFD75587.1| LOW QUALITY PROTEIN: early secretory antigenic target protein
[Mycobacterium tuberculosis GM 1503]
Length=97
Score = 108 bits (271), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 54/57 (95%), Positives = 54/57 (95%), Gaps = 0/57 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQK 57
MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQG K
Sbjct 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGCPAK 57
>gi|58220781|gb|AAW68022.1| ESAT-6 [Mycobacterium ulcerans]
gi|58220785|gb|AAW68024.1| ESAT-6 [Mycobacterium ulcerans]
Length=56
Score = 101 bits (252), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 51/56 (92%), Positives = 53/56 (95%), Gaps = 0/56 (0%)
Query 2 TEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQK 57
TEQQWNFAGIEAA+S+I GNV SIHSLLDEGKQSL KLAAAWGGSGSEAYQGVQQK
Sbjct 1 TEQQWNFAGIEAASSSIGGNVGSIHSLLDEGKQSLHKLAAAWGGSGSEAYQGVQQK 56
>gi|58220777|gb|AAW68020.1| ESAT-6 [Mycobacterium ulcerans]
Length=56
Score = 100 bits (248), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 50/56 (90%), Positives = 53/56 (95%), Gaps = 0/56 (0%)
Query 2 TEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQK 57
TEQQWNFAGIEAA+S+I GNV SIHSLLDEGKQSL +LAAAWGGSGSEAYQGVQQK
Sbjct 1 TEQQWNFAGIEAASSSIGGNVGSIHSLLDEGKQSLHELAAAWGGSGSEAYQGVQQK 56
>gi|145221361|ref|YP_001132039.1| early secretory antigenic target, 6 kDa [Mycobacterium gilvum
PYR-GCK]
gi|315441755|ref|YP_004074634.1| hypothetical protein Mspyr1_00650 [Mycobacterium sp. Spyr1]
gi|145213847|gb|ABP43251.1| early secretory antigenic target, 6 kDa [Mycobacterium gilvum
PYR-GCK]
gi|315260058|gb|ADT96799.1| uncharacterized conserved protein [Mycobacterium sp. Spyr1]
Length=94
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 43/90 (48%), Positives = 59/90 (66%), Gaps = 0/90 (0%)
Query 6 WNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATEL 65
+NFAGI+ A I G V LL EG+ SL +L+A WGG+ S+AY VQ +WD+++ EL
Sbjct 5 YNFAGIDNNAGEIMGAVGRTEGLLQEGQGSLARLSAVWGGTASDAYVAVQNRWDSSSNEL 64
Query 66 NNALQNLARTISEAGQAMASTEGNVTGMFA 95
N AL++LA I++AG M +TE G FA
Sbjct 65 NMALKSLANAIAQAGHDMGATEMRNQGKFA 94
>gi|183980229|ref|YP_001848520.1| EsxA-like protein, EsxA_2 [Mycobacterium marinum M]
gi|183173555|gb|ACC38665.1| conserved hypothetical EsxA-like protein, EsxA_2 [Mycobacterium
marinum M]
Length=95
Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 42/95 (45%), Positives = 54/95 (57%), Gaps = 0/95 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M +NFA IE + IQ V L + Q L+ L WGGSGSEAYQ VQQ+WD
Sbjct 1 MAVLHYNFAAIEIGVAEIQAEVIKTQKHLHDANQVLSTLTEVWGGSGSEAYQQVQQQWDG 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVTGMFA 95
+ +LN ALQ LA I ++ Q M +TE + +FA
Sbjct 61 ASADLNAALQALAHAIHQSNQEMLTTETGLATLFA 95
>gi|183980223|ref|YP_001848514.1| EsxA-like protein, EsxA_3 [Mycobacterium marinum M]
gi|183173549|gb|ACC38659.1| conserved hypothetical EsxA-like protein, EsxA_3 [Mycobacterium
marinum M]
Length=95
Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 40/91 (44%), Positives = 54/91 (60%), Gaps = 0/91 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
+NFA IE + IQ V L + Q L+ L WGGSGSEAYQ VQQ+WD+ + +
Sbjct 5 HYNFAAIEIGVAEIQAEVIKTQKHLHDANQVLSTLTEVWGGSGSEAYQQVQQQWDSASAD 64
Query 65 LNNALQNLARTISEAGQAMASTEGNVTGMFA 95
LN ALQ LA I ++ Q M +TE + +F+
Sbjct 65 LNAALQALAHAIHQSNQEMLTTETGLATLFS 95
>gi|221229377|ref|YP_002502793.1| putative secreted protein [Mycobacterium leprae Br4923]
gi|975683|emb|CAA62441.1| L-esat [Mycobacterium leprae]
gi|219932484|emb|CAR70142.1| possible secreted protein [Mycobacterium leprae Br4923]
Length=95
Score = 76.3 bits (186), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 35/91 (39%), Positives = 61/91 (68%), Gaps = 0/91 (0%)
Query 4 QQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATAT 63
Q W+F ++ A + +QG+ + I +LL++ ++SLTKL ++W GSG+E+Y VQQ+++
Sbjct 3 QAWHFPALQGAVNELQGSQSRIDALLEQCQESLTKLQSSWHGSGNESYSSVQQRFNQNTE 62
Query 64 ELNNALQNLARTISEAGQAMASTEGNVTGMF 94
+N+AL +L + I+ + + M TE VT MF
Sbjct 63 GINHALGDLVQAINHSAETMQQTEAGVTSMF 93
>gi|120401107|ref|YP_950936.1| 6 kDa early secretory antigenic target EsaT6 (EsaT-6) [Mycobacterium
vanbaalenii PYR-1]
gi|119953925|gb|ABM10930.1| 6 kDa early secretory antigenic target EsaT6 (EsaT-6) [Mycobacterium
vanbaalenii PYR-1]
Length=93
Score = 73.2 bits (178), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 39/89 (44%), Positives = 52/89 (59%), Gaps = 0/89 (0%)
Query 6 WNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATEL 65
+NFAGIE+ A I G V + LL EG +LT+L A W G G AY VQ +W+ + EL
Sbjct 4 YNFAGIESDAGEISGQVGKVAGLLAEGHGALTRLQAVWTGDGQMAYDAVQNRWNQNSEEL 63
Query 66 NNALQNLARTISEAGQAMASTEGNVTGMF 94
N ALQ+L+ +S +G M + V G F
Sbjct 64 NLALQSLSEALSRSGGDMFGADQGVAGQF 92
>gi|15826899|ref|NP_301162.1| hypothetical protein ML0049 [Mycobacterium leprae TN]
gi|7531113|sp|Q50206.2|ESXA_MYCLE RecName: Full=6 kDa early secretory antigenic target homolog;
AltName: Full=ESAT-6-like protein; AltName: Full=L-ESAT
gi|2370279|emb|CAA75200.1| probable ESAT-6-like protein [Mycobacterium leprae]
gi|13092446|emb|CAC29557.1| possible secreted protein [Mycobacterium leprae]
Length=95
Score = 73.2 bits (178), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 33/91 (37%), Positives = 60/91 (66%), Gaps = 0/91 (0%)
Query 4 QQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATAT 63
Q W+F ++ A + +QG+ + I +LL++ ++SLTKL ++W GSG+E+Y VQ++++
Sbjct 3 QAWHFPALQGAVNELQGSQSRIDALLEQCQESLTKLQSSWHGSGNESYSSVQRRFNQNTE 62
Query 64 ELNNALQNLARTISEAGQAMASTEGNVTGMF 94
+N+AL +L + I+ + + M TE V MF
Sbjct 63 GINHALGDLVQAINHSAETMQQTEAGVMSMF 93
>gi|334563185|ref|ZP_08516176.1| hypothetical protein CbovD2_01311 [Corynebacterium bovis DSM
20582]
Length=93
Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 31/80 (39%), Positives = 48/80 (60%), Gaps = 0/80 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
+++FA I AA+ IQ + ++LD+ +Q L + A W G ++AYQ Q++WDA A E
Sbjct 3 RYDFAQIAQAATDIQATNGRVGTMLDQLRQDLAPMVAEWQGDSADAYQAAQRRWDAAAEE 62
Query 65 LNNALQNLARTISEAGQAMA 84
LN L +AR + +A MA
Sbjct 63 LNAVLSTIARAVGDANDRMA 82
>gi|38233168|ref|NP_938935.1| ESAT-6-like protein [Corynebacterium diphtheriae NCTC 13129]
gi|38199427|emb|CAE49071.1| Conserved hypothetical ESAT-6-like protein [Corynebacterium diphtheriae]
Length=95
Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 33/84 (40%), Positives = 51/84 (61%), Gaps = 0/84 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M + ++ F IEAAAS IQ I+SLL++ K + +AAAW G ++AY QQ+WD+
Sbjct 1 MEKIKYGFGEIEAAASDIQSTSGRINSLLEDLKAHIRPMAAAWEGESAQAYNEAQQQWDS 60
Query 61 TATELNNALQNLARTISEAGQAMA 84
+A ELN L ++ T+ + M+
Sbjct 61 SAAELNTILSTISNTVRQGNDRMS 84
>gi|68536837|ref|YP_251542.1| hypothetical protein jk1747 [Corynebacterium jeikeium K411]
gi|260579196|ref|ZP_05847086.1| conserved hypothetical ESAT-6-like protein [Corynebacterium jeikeium
ATCC 43734]
gi|68264436|emb|CAI37924.1| hypothetical protein jk1747 [Corynebacterium jeikeium K411]
gi|258602682|gb|EEW15969.1| conserved hypothetical ESAT-6-like protein [Corynebacterium jeikeium
ATCC 43734]
Length=93
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 33/91 (37%), Positives = 51/91 (57%), Gaps = 0/91 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
Q+NFA I AA I +I+ LL + K+ L + + W G+ S++YQ Q+KWD +A E
Sbjct 3 QYNFAQIANAADDINRGNGTINGLLGDLKRDLQPMVSEWEGAASDSYQAAQKKWDTSAQE 62
Query 65 LNNALQNLARTISEAGQAMASTEGNVTGMFA 95
+N L +ART+ +A M+ N +A
Sbjct 63 INEVLGQIARTVRQANDRMSEINTNAANSWA 93
>gi|305679881|ref|ZP_07402691.1| WXG100 family type VII secretion target [Corynebacterium matruchotii
ATCC 14266]
gi|305660501|gb|EFM49998.1| WXG100 family type VII secretion target [Corynebacterium matruchotii
ATCC 14266]
Length=95
Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 33/80 (42%), Positives = 45/80 (57%), Gaps = 0/80 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
++ F+ I+AAA+ IQ + I SLL K + + AW GS S AYQ Q KWD +A E
Sbjct 5 KYGFSEIDAAAADIQTTASRIGSLLHTLKSQIQPMVTAWEGSSSTAYQEAQAKWDHSADE 64
Query 65 LNNALQNLARTISEAGQAMA 84
LN L +ART+ M+
Sbjct 65 LNTILDTIARTVRNGNDDMS 84
>gi|225020500|ref|ZP_03709692.1| hypothetical protein CORMATOL_00507 [Corynebacterium matruchotii
ATCC 33806]
gi|224946889|gb|EEG28098.1| hypothetical protein CORMATOL_00507 [Corynebacterium matruchotii
ATCC 33806]
Length=95
Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 0/80 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
++ F+ I+AA + IQ + I SLL K + + AW GS S AYQ Q KWD +A E
Sbjct 5 KYGFSEIDAATADIQTTASRIGSLLHTLKSQIQPMVTAWEGSSSTAYQEAQAKWDHSADE 64
Query 65 LNNALQNLARTISEAGQAMA 84
LN L +ART+ M+
Sbjct 65 LNTILDTIARTVRNGNDDMS 84
>gi|213964911|ref|ZP_03393110.1| conserved hypothetical protein [Corynebacterium amycolatum SK46]
gi|213952447|gb|EEB63830.1| conserved hypothetical protein [Corynebacterium amycolatum SK46]
Length=95
Score = 60.5 bits (145), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 30/84 (36%), Positives = 48/84 (58%), Gaps = 0/84 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M +++F GI+ AA I+ +I+ LL + K+ + + + W G S++YQ Q++WD
Sbjct 1 MQPIRYSFGGIDGAADDIRSTSGTINGLLGDLKKRIAPMVSTWEGESSDSYQEAQREWDT 60
Query 61 TATELNNALQNLARTISEAGQAMA 84
A ELN L +A T+S Q MA
Sbjct 61 AAEELNMILTTIADTVSAGSQRMA 84
>gi|296394878|ref|YP_003659762.1| hypothetical protein Srot_2494 [Segniliparus rotundus DSM 44985]
gi|296182025|gb|ADG98931.1| protein of unknown function DUF909 [Segniliparus rotundus DSM
44985]
Length=96
Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 30/90 (34%), Positives = 49/90 (55%), Gaps = 0/90 (0%)
Query 6 WNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATEL 65
++FA I+ ++ IQ I SLL E + KLAA W G E + +Q KW+ A +L
Sbjct 6 YDFAHIQELSTQIQSVSQQIESLLGELSSEVAKLAAGWEGEAQETWHALQTKWNQEADDL 65
Query 66 NNALQNLARTISEAGQAMASTEGNVTGMFA 95
L +L+ + +AG++M E ++T F+
Sbjct 66 KTTLHDLSSKVGQAGESMQHAESSITSKFS 95
>gi|227541777|ref|ZP_03971826.1| ESAT-6 family protein [Corynebacterium glucuronolyticum ATCC
51866]
gi|227182483|gb|EEI63455.1| ESAT-6 family protein [Corynebacterium glucuronolyticum ATCC
51866]
Length=96
Score = 58.5 bits (140), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 27/80 (34%), Positives = 46/80 (58%), Gaps = 0/80 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
+++F I AA++ ++ I+ LL + K +T + + W G + AYQ Q +WD A E
Sbjct 6 RYDFGAISAASADMRATSGRINGLLGDLKSQITPMVSTWEGDSAVAYQDAQNRWDRAAGE 65
Query 65 LNNALQNLARTISEAGQAMA 84
LN L+ +ART+ + Q M+
Sbjct 66 LNQILETIARTVEDGNQRMS 85
>gi|256380551|ref|YP_003104211.1| hypothetical protein Amir_6566 [Actinosynnema mirum DSM 43827]
gi|255924854|gb|ACU40365.1| protein of unknown function DUF909 [Actinosynnema mirum DSM 43827]
Length=96
Score = 58.2 bits (139), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 31/88 (36%), Positives = 46/88 (53%), Gaps = 0/88 (0%)
Query 7 NFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATELN 66
+F + AA I G+ T + + LDE KQ + + A W G SE YQ Q+KWD A +L
Sbjct 8 DFGQLSGAAGDISGHATKVQTELDELKQRIAPVVAQWDGVSSETYQEAQRKWDTAAADLQ 67
Query 67 NALQNLARTISEAGQAMASTEGNVTGMF 94
L ++ ++ A +A S E TG +
Sbjct 68 QVLASIGTAVAAATEAYQSAEQRNTGRW 95
>gi|296119294|ref|ZP_06837862.1| early secretory antigenic target EsaT6 [Corynebacterium ammoniagenes
DSM 20306]
gi|295967686|gb|EFG80943.1| early secretory antigenic target EsaT6 [Corynebacterium ammoniagenes
DSM 20306]
Length=95
Score = 57.8 bits (138), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 30/84 (36%), Positives = 46/84 (55%), Gaps = 0/84 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M+E ++ F I AA+ I + I+ LLD+ K + +AA W G + AY Q KWD
Sbjct 1 MSEIKYQFGAISNAAADINSTSSRINGLLDDLKGVIAPMAATWEGESAAAYNEAQAKWDN 60
Query 61 TATELNNALQNLARTISEAGQAMA 84
A ELN L ++ T+S++ M+
Sbjct 61 AAAELNTVLATISNTVSQSNDRMS 84
>gi|19551814|ref|NP_599816.1| hypothetical protein NCgl0555 [Corynebacterium glutamicum ATCC
13032]
gi|62389469|ref|YP_224871.1| hypothetical protein cg0672 [Corynebacterium glutamicum ATCC
13032]
gi|145294750|ref|YP_001137571.1| hypothetical protein cgR_0698 [Corynebacterium glutamicum R]
gi|21323345|dbj|BAB97973.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]
gi|41324803|emb|CAF19285.1| conserved HYPOTHETICAL PROTEIN [Corynebacterium glutamicum ATCC
13032]
gi|140844670|dbj|BAF53669.1| hypothetical protein [Corynebacterium glutamicum R]
gi|344045944|gb|EGV41613.1| hypothetical protein CgS9114_02353 [Corynebacterium glutamicum
S9114]
Length=96
Score = 57.4 bits (137), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 30/82 (37%), Positives = 44/82 (54%), Gaps = 0/82 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
++ F I+ AA+ I I+SLLD K L + A+W G SEAY Q KWD A E
Sbjct 5 RYEFGAIQGAATDINSTSGRINSLLDGLKSQLQPMVASWEGESSEAYSEAQLKWDRAAAE 64
Query 65 LNNALQNLARTISEAGQAMAST 86
LN L ++ T+++ + M+
Sbjct 65 LNTILATISNTVAQGAERMSDV 86
>gi|25027139|ref|NP_737193.1| hypothetical protein CE0583 [Corynebacterium efficiens YS-314]
gi|259506729|ref|ZP_05749629.1| conserved hypothetical ESAT-6-like protein [Corynebacterium efficiens
YS-314]
gi|23492419|dbj|BAC17393.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]
gi|259165670|gb|EEW50224.1| conserved hypothetical ESAT-6-like protein [Corynebacterium efficiens
YS-314]
Length=96
Score = 57.0 bits (136), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 30/82 (37%), Positives = 44/82 (54%), Gaps = 0/82 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
++ F I+ AA+ I I+SLLD KQ L + A W G + AY Q KWD A E
Sbjct 5 RYEFGAIQGAATDINSTSGRINSLLDGLKQQLQPMVATWEGDSAVAYNEAQMKWDNAAAE 64
Query 65 LNNALQNLARTISEAGQAMAST 86
LN L +++T+S+ + M+
Sbjct 65 LNTILATISQTVSQGAERMSDV 86
>gi|227487060|ref|ZP_03917376.1| ESAT-6 family protein [Corynebacterium glucuronolyticum ATCC
51867]
gi|227093134|gb|EEI28446.1| ESAT-6 family protein [Corynebacterium glucuronolyticum ATCC
51867]
Length=96
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 45/80 (57%), Gaps = 0/80 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
+++F I AA++ ++ I+ LL + K + + + W G + AYQ Q +WD A E
Sbjct 6 RYDFGAISAASADMRATSGRINGLLGDLKSQIAPMVSTWEGDSAVAYQDAQNRWDRAAGE 65
Query 65 LNNALQNLARTISEAGQAMA 84
LN L+ +ART+ + Q M+
Sbjct 66 LNQILETIARTVEDGNQRMS 85
>gi|300857819|ref|YP_003782802.1| hypothetical protein cpfrc_00402 [Corynebacterium pseudotuberculosis
FRC41]
gi|300685273|gb|ADK28195.1| hypothetical protein cpfrc_00402 [Corynebacterium pseudotuberculosis
FRC41]
gi|302205555|gb|ADL09897.1| ESAT-6-like protein [Corynebacterium pseudotuberculosis C231]
gi|302330110|gb|ADL20304.1| ESAT-6-like protein [Corynebacterium pseudotuberculosis 1002]
gi|308275790|gb|ADO25689.1| ESAT-6-like protein [Corynebacterium pseudotuberculosis I19]
gi|341824218|gb|AEK91739.1| ESAT-6-like protein [Corynebacterium pseudotuberculosis PAT10]
Length=93
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 29/80 (37%), Positives = 43/80 (54%), Gaps = 0/80 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
++ FA IE AA IQ I SLL+E K + + + W G + AYQ Q +WD A E
Sbjct 3 KYGFAAIEGAAGDIQSTSVRISSLLEELKAGIRPMVSTWEGDSALAYQEAQSQWDQAAYE 62
Query 65 LNNALQNLARTISEAGQAMA 84
LN L +++T+ + M+
Sbjct 63 LNTILSTISQTVRAGNERMS 82
>gi|227502708|ref|ZP_03932757.1| ESAT-6 family protein [Corynebacterium accolens ATCC 49725]
gi|306835284|ref|ZP_07468313.1| conserved hypothetical protein [Corynebacterium accolens ATCC
49726]
gi|227076438|gb|EEI14401.1| ESAT-6 family protein [Corynebacterium accolens ATCC 49725]
gi|304568828|gb|EFM44364.1| conserved hypothetical protein [Corynebacterium accolens ATCC
49726]
Length=95
Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 29/84 (35%), Positives = 45/84 (54%), Gaps = 0/84 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M+E ++ F I +AA+ I I+S L + K L + + W G + AY Q KWD
Sbjct 1 MSEIKYQFGAISSAAADINATSGRINSTLADLKSRLQPMVSTWEGESAVAYNQAQAKWDK 60
Query 61 TATELNNALQNLARTISEAGQAMA 84
A ELN L +++T+S+ AM+
Sbjct 61 AAQELNTVLATISKTVSQGNDAMS 84
>gi|337290070|ref|YP_004629091.1| hypothetical protein CULC22_00454 [Corynebacterium ulcerans BR-AD22]
gi|334696193|gb|AEG80990.1| hypothetical protein CULC809_00450 [Corynebacterium ulcerans
809]
gi|334698376|gb|AEG83172.1| hypothetical protein CULC22_00454 [Corynebacterium ulcerans BR-AD22]
Length=93
Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 0/80 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
++ FA IE AA IQ + SLL++ K S+ + + W G + AYQ Q +WD A E
Sbjct 3 KYGFAAIEGAAGDIQSTSGRMSSLLEDLKTSIRPMVSTWEGDSALAYQEAQSQWDQAAYE 62
Query 65 LNNALQNLARTISEAGQAMA 84
LN L +++T+ + M+
Sbjct 63 LNTILSTISQTVRAGNERMS 82
>gi|229821686|ref|YP_002883212.1| hypothetical protein Bcav_3206 [Beutenbergia cavernae DSM 12333]
gi|229821691|ref|YP_002883217.1| hypothetical protein Bcav_3211 [Beutenbergia cavernae DSM 12333]
gi|229567599|gb|ACQ81450.1| protein of unknown function DUF909 [Beutenbergia cavernae DSM
12333]
gi|229567604|gb|ACQ81455.1| protein of unknown function DUF909 [Beutenbergia cavernae DSM
12333]
Length=94
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 29/91 (32%), Positives = 43/91 (48%), Gaps = 0/91 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M + + NF I AA+ IQ + S LD Q L L A W G S+AY+ + KW
Sbjct 1 MVDMRVNFGAIATAAADIQSGANEVQSTLDSMDQQLQPLRANWTGEASQAYEAAKAKWST 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNVT 91
T++ L ++ R + G+ +TE T
Sbjct 61 AITDMKTLLADIGREVQTGGEDYQATESRNT 91
>gi|332669470|ref|YP_004452478.1| hypothetical protein Celf_0954 [Cellulomonas fimi ATCC 484]
gi|332338508|gb|AEE45091.1| protein of unknown function DUF909 [Cellulomonas fimi ATCC 484]
Length=94
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 29/87 (34%), Positives = 47/87 (55%), Gaps = 0/87 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M++ + NF G+ AA+ IQ I S L++ SL L A W G S +Y+ + KW A
Sbjct 1 MSDLKVNFGGLATAAADIQSGANQIESRLNDLDSSLQPLRANWSGEASASYEAAKAKWTA 60
Query 61 TATELNNALQNLARTISEAGQAMASTE 87
T++ L ++ R ++ +G+ STE
Sbjct 61 AITDMKALLADVGRAVATSGEEYQSTE 87
>gi|311898690|dbj|BAJ31098.1| hypothetical protein KSE_53230 [Kitasatospora setae KM-6054]
Length=96
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 27/81 (34%), Positives = 45/81 (56%), Gaps = 0/81 (0%)
Query 7 NFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATELN 66
NF I++A+S ++ I S LD+ K + ++A++W G+ + YQ Q +WDA A +L
Sbjct 7 NFQTIQSASSEVRQTAARIQSQLDDLKSGVQRIASSWEGAAQQGYQARQAQWDAKAADLQ 66
Query 67 NALQNLARTISEAGQAMASTE 87
L +A + A Q+ TE
Sbjct 67 QVLGRIAAALDNAAQSYQQTE 87
>gi|255324788|ref|ZP_05365902.1| conserved hypothetical protein [Corynebacterium tuberculostearicum
SK141]
gi|311740021|ref|ZP_07713855.1| conserved hypothetical protein [Corynebacterium pseudogenitalium
ATCC 33035]
gi|255298263|gb|EET77566.1| conserved hypothetical protein [Corynebacterium tuberculostearicum
SK141]
gi|311305094|gb|EFQ81163.1| conserved hypothetical protein [Corynebacterium pseudogenitalium
ATCC 33035]
Length=95
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 28/84 (34%), Positives = 45/84 (54%), Gaps = 0/84 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M+E ++ F I +AA+ I I+S L + K L + + W G + AY Q KWD
Sbjct 1 MSEIKYEFGAISSAAADINATSGRINSTLADLKARLQPMVSTWEGESAVAYNQAQAKWDK 60
Query 61 TATELNNALQNLARTISEAGQAMA 84
+ ELN L +++T+S+ AM+
Sbjct 61 ASQELNTVLATISKTVSQGNDAMS 84
>gi|172040054|ref|YP_001799768.1| hypothetical protein cur_0374 [Corynebacterium urealyticum DSM
7109]
gi|171851358|emb|CAQ04334.1| hypothetical protein cu0374 [Corynebacterium urealyticum DSM
7109]
Length=93
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 30/80 (38%), Positives = 41/80 (52%), Gaps = 0/80 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
++NF I A I I+ L++ KQ L L A W G SEAYQ Q +WD A E
Sbjct 3 KYNFGMIAQTADDINQTRGRINGNLEDLKQQLQPLVADWEGESSEAYQQAQLRWDRAAAE 62
Query 65 LNNALQNLARTISEAGQAMA 84
LN L ++ T+ +A M+
Sbjct 63 LNEVLGQISVTVRQANDRMS 82
>gi|330470640|ref|YP_004408383.1| hypothetical protein VAB18032_03495 [Verrucosispora maris AB-18-032]
gi|328813611|gb|AEB47783.1| hypothetical protein VAB18032_03495 [Verrucosispora maris AB-18-032]
Length=95
Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 28/85 (33%), Positives = 47/85 (56%), Gaps = 0/85 (0%)
Query 3 EQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATA 62
E ++NFAG+ AAA + +V ++ S L+ K + L A W G EAY Q++W++ A
Sbjct 2 EIRYNFAGLNAAADSCGSSVRNMTSELEGLKSGIAPLLATWDGDAREAYFQRQREWESAA 61
Query 63 TELNNALQNLARTISEAGQAMASTE 87
+L + L + R + E+ M + E
Sbjct 62 NDLRDLLGRIERALRESAGKMQARE 86
>gi|227549882|ref|ZP_03979931.1| conserved hypothetical protein [Corynebacterium lipophiloflavum
DSM 44291]
gi|227078028|gb|EEI15991.1| conserved hypothetical protein [Corynebacterium lipophiloflavum
DSM 44291]
Length=94
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 24/72 (34%), Positives = 43/72 (60%), Gaps = 0/72 (0%)
Query 5 QWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDATATE 64
++ F + AA ++G+V I+ +LDE K L + + W G +EAY+ Q +WD+ A++
Sbjct 4 KYEFGQLAGAAEDLRGSVAHINRMLDELKSGLQPMVSTWTGDAAEAYKVHQSEWDSAASD 63
Query 65 LNNALQNLARTI 76
LN L ++A +
Sbjct 64 LNAILNSVAEAV 75
>gi|169629412|ref|YP_001703061.1| hypothetical protein MAB_2326c [Mycobacterium abscessus ATCC
19977]
gi|169241379|emb|CAM62407.1| Hypothetical protein MAB_2326c [Mycobacterium abscessus]
Length=100
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 31/90 (35%), Positives = 48/90 (54%), Gaps = 0/90 (0%)
Query 1 MTEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSGSEAYQGVQQKWDA 60
M + +++A I A Q ++ + LLDE + + KLA +W G+ +A++ Q+ W
Sbjct 1 MADLVYDYAKISALVGDWQASIARLQQLLDEQRAEVNKLAESWTGATGDAFRREQKIWQQ 60
Query 61 TATELNNALQNLARTISEAGQAMASTEGNV 90
TA L A + L IS A +AMA TE V
Sbjct 61 TADTLLAAAKKLGGLISAAAEAMAKTEAGV 90
Lambda K H
0.307 0.119 0.333
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 131599744116
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40