BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3893c

Length=77
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|340628865|ref|YP_004747317.1|  PE family protein [Mycobacteriu...   148    2e-34
gi|15843524|ref|NP_338561.1|  PE family protein [Mycobacterium tu...   147    5e-34
gi|339633883|ref|YP_004725525.1|  PE family protein [Mycobacteriu...   146    1e-33
gi|297733574|ref|ZP_06962692.1|  PE family protein [Mycobacterium...   136    9e-31
gi|296167009|ref|ZP_06849422.1|  PE2 family protein [Mycobacteriu...   103    8e-21
gi|41406255|ref|NP_959091.1|  hypothetical protein MAP0157 [Mycob...   103    8e-21
gi|342860128|ref|ZP_08716780.1|  PE family protein [Mycobacterium...   102    3e-20
gi|254773504|ref|ZP_05215020.1|  PE family protein [Mycobacterium...  92.8    2e-17
gi|240168373|ref|ZP_04747032.1|  PE family protein [Mycobacterium...  89.0    2e-16
gi|254822563|ref|ZP_05227564.1|  PE family protein [Mycobacterium...  85.1    3e-15
gi|333988696|ref|YP_004521310.1|  hypothetical protein JDM601_005...  68.6    3e-10
gi|240170857|ref|ZP_04749516.1|  hypothetical protein MkanA1_1620...  40.0    0.11 
gi|240170359|ref|ZP_04749018.1|  hypothetical protein MkanA1_1368...  36.6    1.4  
gi|169245932|gb|ACA50953.1|  hypothetical protein MUDP_036 [Mycob...  34.7    5.4  


>gi|340628865|ref|YP_004747317.1| PE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340007055|emb|CCC46246.1| PE family protein [Mycobacterium canettii CIPT 140010059]
Length=101

 Score =  148 bits (374),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 77/77 (100%), Positives = 77/77 (100%), Gaps = 0/77 (0%)

Query  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60
           MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS
Sbjct  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60

Query  61  YLGVVAEHASQRGLFAG  77
           YLGVVAEHASQRGLFAG
Sbjct  61  YLGVVAEHASQRGLFAG  77


>gi|15843524|ref|NP_338561.1| PE family protein [Mycobacterium tuberculosis CDC1551]
 gi|31795066|ref|NP_857559.1| PE family protein [Mycobacterium bovis AF2122/97]
 gi|57117167|ref|YP_178025.1| PE family protein [Mycobacterium tuberculosis H37Rv]
 60 more sequence titles
 
gi|121639804|ref|YP_980028.1| PE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|148663760|ref|YP_001285283.1| PE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148825101|ref|YP_001289855.1| PE family protein [Mycobacterium tuberculosis F11]
 gi|167969431|ref|ZP_02551708.1| PE family protein [Mycobacterium tuberculosis H37Ra]
 gi|224992299|ref|YP_002646989.1| PE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|253800943|ref|YP_003033945.1| PE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|254233379|ref|ZP_04926705.1| PE family protein [Mycobacterium tuberculosis C]
 gi|254366433|ref|ZP_04982477.1| PE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|254548897|ref|ZP_05139344.1| PE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|289441335|ref|ZP_06431079.1| PE family protein [Mycobacterium tuberculosis T46]
 gi|289445494|ref|ZP_06435238.1| PE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289556162|ref|ZP_06445372.1| PE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289572150|ref|ZP_06452377.1| PE family protein [Mycobacterium tuberculosis T17]
 gi|289572546|ref|ZP_06452773.1| PE family protein [Mycobacterium tuberculosis K85]
 gi|289747738|ref|ZP_06507116.1| PE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289748429|ref|ZP_06507807.1| PE family protein [Mycobacterium tuberculosis T92]
 gi|289756028|ref|ZP_06515406.1| predicted protein [Mycobacterium tuberculosis EAS054]
 gi|289760065|ref|ZP_06519443.1| predicted protein [Mycobacterium tuberculosis T85]
 gi|289764085|ref|ZP_06523463.1| PE family protein [Mycobacterium tuberculosis GM 1503]
 gi|294995578|ref|ZP_06801269.1| PE family protein [Mycobacterium tuberculosis 210]
 gi|297636579|ref|ZP_06954359.1| PE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|298527366|ref|ZP_07014775.1| PE family protein [Mycobacterium tuberculosis 94_M4241A]
 gi|306786944|ref|ZP_07425266.1| PE family protein [Mycobacterium tuberculosis SUMu004]
 gi|306791498|ref|ZP_07429800.1| PE family protein [Mycobacterium tuberculosis SUMu005]
 gi|306795563|ref|ZP_07433865.1| PE family protein [Mycobacterium tuberculosis SUMu006]
 gi|306805746|ref|ZP_07442414.1| PE family protein [Mycobacterium tuberculosis SUMu007]
 gi|306970143|ref|ZP_07482804.1| PE family protein [Mycobacterium tuberculosis SUMu009]
 gi|313660905|ref|ZP_07817785.1| PE family protein [Mycobacterium tuberculosis KZN V2475]
 gi|7478586|pir||F70598 probable PE protein - Mycobacterium tuberculosis (strain H37RV)
 gi|13883900|gb|AAK48375.1| PE family protein [Mycobacterium tuberculosis CDC1551]
 gi|31620664|emb|CAD96108.1| PE FAMILY PROTEIN [Mycobacterium bovis AF2122/97]
 gi|38490391|emb|CAE55650.1| PE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|121495452|emb|CAL73939.1| PE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|124603172|gb|EAY61447.1| PE family protein [Mycobacterium tuberculosis C]
 gi|134151945|gb|EBA43990.1| PE family protein [Mycobacterium tuberculosis str. Haarlem]
 gi|148507912|gb|ABQ75721.1| PE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148723628|gb|ABR08253.1| PE family protein [Mycobacterium tuberculosis F11]
 gi|224775415|dbj|BAH28221.1| PE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|253322447|gb|ACT27050.1| PE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289414254|gb|EFD11494.1| PE family protein [Mycobacterium tuberculosis T46]
 gi|289418452|gb|EFD15653.1| PE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289440794|gb|EFD23287.1| PE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289536977|gb|EFD41555.1| PE family protein [Mycobacterium tuberculosis K85]
 gi|289545905|gb|EFD49552.1| PE family protein [Mycobacterium tuberculosis T17]
 gi|289688266|gb|EFD55754.1| PE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289689016|gb|EFD56445.1| PE family protein [Mycobacterium tuberculosis T92]
 gi|289696615|gb|EFD64044.1| predicted protein [Mycobacterium tuberculosis EAS054]
 gi|289711591|gb|EFD75607.1| PE family protein [Mycobacterium tuberculosis GM 1503]
 gi|289715629|gb|EFD79641.1| predicted protein [Mycobacterium tuberculosis T85]
 gi|298497160|gb|EFI32454.1| PE family protein [Mycobacterium tuberculosis 94_M4241A]
 gi|308336347|gb|EFP25198.1| PE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308339958|gb|EFP28809.1| PE family protein [Mycobacterium tuberculosis SUMu005]
 gi|308343860|gb|EFP32711.1| PE family protein [Mycobacterium tuberculosis SUMu006]
 gi|308347645|gb|EFP36496.1| PE family protein [Mycobacterium tuberculosis SUMu007]
 gi|308352270|gb|EFP41121.1| PE family protein [Mycobacterium tuberculosis SUMu009]
 gi|323717309|gb|EGB26514.1| PE family protein [Mycobacterium tuberculosis CDC1551A]
 gi|326905728|gb|EGE52661.1| PE family protein [Mycobacterium tuberculosis W-148]
 gi|328460671|gb|AEB06094.1| PE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|341603825|emb|CCC66506.1| PE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
 gi|344221733|gb|AEN02364.1| PE family protein [Mycobacterium tuberculosis CTRI-2]
Length=77

 Score =  147 bits (371),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 77/77 (100%), Positives = 77/77 (100%), Gaps = 0/77 (0%)

Query  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60
           MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS
Sbjct  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60

Query  61  YLGVVAEHASQRGLFAG  77
           YLGVVAEHASQRGLFAG
Sbjct  61  YLGVVAEHASQRGLFAG  77


>gi|339633883|ref|YP_004725525.1| PE family protein [Mycobacterium africanum GM041182]
 gi|339333239|emb|CCC28976.1| PE family protein [Mycobacterium africanum GM041182]
Length=77

 Score =  146 bits (368),  Expect = 1e-33, Method: Compositional matrix adjust.
 Identities = 76/77 (99%), Positives = 76/77 (99%), Gaps = 0/77 (0%)

Query  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60
           MVWSVQPE VLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS
Sbjct  1   MVWSVQPETVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60

Query  61  YLGVVAEHASQRGLFAG  77
           YLGVVAEHASQRGLFAG
Sbjct  61  YLGVVAEHASQRGLFAG  77


>gi|297733574|ref|ZP_06962692.1| PE family protein [Mycobacterium tuberculosis KZN R506]
Length=73

 Score =  136 bits (343),  Expect = 9e-31, Method: Compositional matrix adjust.
 Identities = 72/73 (99%), Positives = 73/73 (100%), Gaps = 0/73 (0%)

Query  5   VQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGASYLGV  64
           +QPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGASYLGV
Sbjct  1   MQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGASYLGV  60

Query  65  VAEHASQRGLFAG  77
           VAEHASQRGLFAG
Sbjct  61  VAEHASQRGLFAG  73


>gi|296167009|ref|ZP_06849422.1| PE2 family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897639|gb|EFG77232.1| PE2 family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=112

 Score =  103 bits (257),  Expect = 8e-21, Method: Compositional matrix adjust.
 Identities = 64/77 (84%), Positives = 70/77 (91%), Gaps = 0/77 (0%)

Query  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60
           M  S+QPEAVLASA AESAISAETEAAA+ AAPALL T PMG DPDSAMF+AALNACGAS
Sbjct  10  MTMSMQPEAVLASAGAESAISAETEAAASAAAPALLGTLPMGSDPDSAMFAAALNACGAS  69

Query  61  YLGVVAEHASQRGLFAG  77
           YLGVV+EH++QRGLFAG
Sbjct  70  YLGVVSEHSAQRGLFAG  86


>gi|41406255|ref|NP_959091.1| hypothetical protein MAP0157 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118462731|ref|YP_879446.1| PE family protein [Mycobacterium avium 104]
 gi|41394603|gb|AAS02474.1| PE_2 [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118164018|gb|ABK64915.1| PE family protein [Mycobacterium avium 104]
 gi|212595750|gb|ACJ35520.1| PE2 [Mycobacterium avium subsp. avium]
 gi|336457763|gb|EGO36759.1| PE family protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=103

 Score =  103 bits (257),  Expect = 8e-21, Method: Compositional matrix adjust.
 Identities = 64/77 (84%), Positives = 69/77 (90%), Gaps = 0/77 (0%)

Query  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60
           MV SVQ E VLASA AESAISAETEAAA+ A+PALL   PMGGDPDSAMF+AALNACGAS
Sbjct  1   MVVSVQSEMVLASAGAESAISAETEAAASAASPALLGVMPMGGDPDSAMFAAALNACGAS  60

Query  61  YLGVVAEHASQRGLFAG  77
           YLGVV+EHA+QRGLFAG
Sbjct  61  YLGVVSEHAAQRGLFAG  77


>gi|342860128|ref|ZP_08716780.1| PE family protein [Mycobacterium colombiense CECT 3035]
 gi|342132506|gb|EGT85735.1| PE family protein [Mycobacterium colombiense CECT 3035]
Length=102

 Score =  102 bits (253),  Expect = 3e-20, Method: Compositional matrix adjust.
 Identities = 60/74 (82%), Positives = 67/74 (91%), Gaps = 0/74 (0%)

Query  4   SVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGASYLG  63
           SVQ EAVLAS++AE+AISAETEAAA+ AAP LL   PMGGDPDSAMF+AALNACG SYLG
Sbjct  5   SVQTEAVLASSSAETAISAETEAAASAAAPVLLGVLPMGGDPDSAMFAAALNACGGSYLG  64

Query  64  VVAEHASQRGLFAG  77
           VV+EHA+QRGLFAG
Sbjct  65  VVSEHAAQRGLFAG  78


>gi|254773504|ref|ZP_05215020.1| PE family protein [Mycobacterium avium subsp. avium ATCC 25291]
Length=95

 Score = 92.8 bits (229),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 58/68 (86%), Positives = 63/68 (93%), Gaps = 0/68 (0%)

Query  10  VLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGASYLGVVAEHA  69
           VLASA AESAISAETEAAA+ A+PALL   PMGGDPDSAMF+AALNACGASYLGVV+EHA
Sbjct  2   VLASAGAESAISAETEAAASAASPALLGVMPMGGDPDSAMFAAALNACGASYLGVVSEHA  61

Query  70  SQRGLFAG  77
           +QRGLFAG
Sbjct  62  AQRGLFAG  69


>gi|240168373|ref|ZP_04747032.1| PE family protein [Mycobacterium kansasii ATCC 12478]
Length=96

 Score = 89.0 bits (219),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 42/45 (94%), Positives = 43/45 (96%), Gaps = 0/45 (0%)

Query  33  PALLSTTPMGGDPDSAMFSAALNACGASYLGVVAEHASQRGLFAG  77
           PALL TTPMG DPDSAMFSAALNACGASYLGVVAEHA+QRGLFAG
Sbjct  29  PALLGTTPMGDDPDSAMFSAALNACGASYLGVVAEHAAQRGLFAG  73


>gi|254822563|ref|ZP_05227564.1| PE family protein [Mycobacterium intracellulare ATCC 13950]
 gi|212596249|gb|ACJ35563.1| PE2 [Mycobacterium intracellulare ATCC 13950]
Length=101

 Score = 85.1 bits (209),  Expect = 3e-15, Method: Compositional matrix adjust.
 Identities = 64/77 (84%), Positives = 70/77 (91%), Gaps = 0/77 (0%)

Query  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60
           MV SVQ EAVLASAAAESAISAETEAAA+ A+P LL   PMGGDPDSAMF+AALNACGAS
Sbjct  1   MVVSVQSEAVLASAAAESAISAETEAAASAASPVLLGVLPMGGDPDSAMFAAALNACGAS  60

Query  61  YLGVVAEHASQRGLFAG  77
           YLGVV+EHA+QRGLF+G
Sbjct  61  YLGVVSEHAAQRGLFSG  77


>gi|333988696|ref|YP_004521310.1| hypothetical protein JDM601_0056 [Mycobacterium sp. JDM601]
 gi|333484664|gb|AEF34056.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=97

 Score = 68.6 bits (166),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 46/73 (64%), Positives = 59/73 (81%), Gaps = 0/73 (0%)

Query  5   VQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGASYLGV  64
           ++PEAVLAS+  E+AI+AET AAA+ A+PALL   PMG DPDS  F AAL A G+ YLG+
Sbjct  1   MEPEAVLASSGVEAAITAETAAAASSASPALLGVLPMGNDPDSIAFQAALLASGSEYLGI  60

Query  65  VAEHASQRGLFAG  77
           VAEH++QRGL++G
Sbjct  61  VAEHSAQRGLYSG  73


>gi|240170857|ref|ZP_04749516.1| hypothetical protein MkanA1_16207 [Mycobacterium kansasii ATCC 
12478]
Length=81

 Score = 40.0 bits (92),  Expect = 0.11, Method: Compositional matrix adjust.
 Identities = 29/75 (39%), Positives = 44/75 (59%), Gaps = 4/75 (5%)

Query  1   MVWSVQPEAVLASAAAESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGAS  60
           +V++V+P  V ASA +++ ++A+  A  AG A AL+   PMG   DSA F+      GA+
Sbjct  2   VVFAVEPAVVGASAVSQAGLAAQHGAGVAGCAAALVGVVPMGEVADSAAFA----GVGAA  57

Query  61  YLGVVAEHASQRGLF  75
           Y+    EHA + G F
Sbjct  58  YVSAAGEHARREGRF  72


>gi|240170359|ref|ZP_04749018.1| hypothetical protein MkanA1_13685 [Mycobacterium kansasii ATCC 
12478]
Length=85

 Score = 36.6 bits (83),  Expect = 1.4, Method: Compositional matrix adjust.
 Identities = 28/59 (48%), Positives = 38/59 (65%), Gaps = 0/59 (0%)

Query  17  ESAISAETEAAAAGAAPALLSTTPMGGDPDSAMFSAALNACGASYLGVVAEHASQRGLF  75
           ++ ++A   A  A AAP L +  PMG D DSA F+AAL A GA+Y+    EHA+ RG+F
Sbjct  3   QAGLAARLGAGVAAAAPTLSAVAPMGEDADSAAFTAALAAVGAAYVSTAGEHAAARGVF  61


>gi|169245932|gb|ACA50953.1| hypothetical protein MUDP_036 [Mycobacterium marinum DL240490]
Length=98

 Score = 34.7 bits (78),  Expect = 5.4, Method: Compositional matrix adjust.
 Identities = 20/44 (46%), Positives = 27/44 (62%), Gaps = 0/44 (0%)

Query  33  PALLSTTPMGGDPDSAMFSAALNACGASYLGVVAEHASQRGLFA  76
           PA+ +  PMGG+  SAM + A+ A GA +L V A   +QR  FA
Sbjct  32  PAMGAMVPMGGEEVSAMLAQAIAAHGAQFLAVGAVGVAQREAFA  75



Lambda     K      H
   0.311    0.120    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 130175841596


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40