BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= ML0139 (2116 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,153,314 sequences; 3,808,957,724 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|Q9CD78|Q9CD78_MYCLE Tax_Id=1769 (mas)SubName: Full=Putative m... 3940 0.0 tr|B8ZTZ2|B8ZTZ2_MYCLB Tax_Id=561304 (mas)SubName: Full=Putative... 3940 0.0 tr|P96291|P96291_MYCTU Tax_Id=1773 (mas)SubName: Full=Mycocerosi... 3453 0.0 tr|C6DWB4|C6DWB4_MYCTK Tax_Id=478434 SubName: Full=Multifunction... 3453 0.0 tr|A5U6U7|A5U6U7_MYCTA Tax_Id=419947 (mas)SubName: Full=Multifun... 3453 0.0 tr|A5WRJ2|A5WRJ2_MYCTF Tax_Id=336982 SubName: Full=Multi-functio... 3453 0.0 tr|A4KKK0|A4KKK0_MYCTU Tax_Id=395095 SubName: Full=Multifunction... 3453 0.0 tr|A2VLR6|A2VLR6_MYCTU Tax_Id=348776 SubName: Full=Multifunction... 3453 0.0 sp|Q02251|MCAS_MYCBO Tax_Id=1765 (mas)RecName: Full=Mycocerosic ... 3451 0.0 tr|C1AG56|C1AG56_MYCBT Tax_Id=561275 (mas)SubName: Full=Putative... 3451 0.0 tr|A1KMT5|A1KMT5_MYCBP Tax_Id=410289 (mas)SubName: Full=Probable... 3451 0.0 tr|B2HIM2|B2HIM2_MYCMM Tax_Id=216594 (mas)SubName: Full=Multifun... 3006 0.0 tr|A0PQ30|A0PQ30_MYCUA Tax_Id=362242 (mas)SubName: Full=Multifun... 2999 0.0 tr|B2HQ46|B2HQ46_MYCMM Tax_Id=216594 (pks5)SubName: Full=Probabl... 2497 0.0 sp|O07798|PHAS_MYCTU Tax_Id=1773 (pks2)RecName: Full=Phthioceran... 2476 0.0 sp|A5U9F4|PHAS_MYCTA Tax_Id=419947 (pks2)RecName: Full=Phthiocer... 2476 0.0 sp|Q7TVK8|PHAS_MYCBO Tax_Id=1765 (pks2)RecName: Full=Phthioceran... 2476 0.0 tr|Q73TF4|Q73TF4_MYCPA Tax_Id=1770 (pks2)SubName: Full=Pks2;[Myc... 2476 0.0 tr|C6DP53|C6DP53_MYCTK Tax_Id=478434 SubName: Full=Polyketide sy... 2476 0.0 tr|A4KMU1|A4KMU1_MYCTU Tax_Id=395095 SubName: Full=Polyketide sy... 2476 0.0 tr|A2VMK1|A2VMK1_MYCTU Tax_Id=348776 SubName: Full=Polyketide sy... 2474 0.0 sp|A1KQG0|PHAS_MYCBP Tax_Id=410289 (pks2)RecName: Full=Phthiocer... 2473 0.0 tr|C1AIT1|C1AIT1_MYCBT Tax_Id=561275 (pks2)SubName: Full=Polyket... 2473 0.0 tr|A5WU45|A5WU45_MYCTF Tax_Id=336982 SubName: Full=Polyketide sy... 2473 0.0 tr|Q7VEZ3|Q7VEZ3_MYCBO Tax_Id=1765 (pks5)SubName: Full=Probable ... 2454 0.0 tr|C1ANG3|C1ANG3_MYCBT Tax_Id=561275 (pks5)SubName: Full=Putativ... 2454 0.0 tr|A1KIV7|A1KIV7_MYCBP Tax_Id=410289 (pks5)SubName: Full=Probabl... 2454 0.0 tr|O53901|O53901_MYCTU Tax_Id=1773 (pks5)SubName: Full=Probable ... 2454 0.0 tr|C6DSR5|C6DSR5_MYCTK Tax_Id=478434 SubName: Full=Polyketide sy... 2454 0.0 tr|A5U2N4|A5U2N4_MYCTA Tax_Id=419947 (pks5)SubName: Full=Putativ... 2454 0.0 tr|A5WML4|A5WML4_MYCTF Tax_Id=336982 SubName: Full=Polyketide sy... 2454 0.0 tr|A2VI44|A2VI44_MYCTU Tax_Id=348776 SubName: Full=Polyketide sy... 2452 0.0 tr|A0QF84|A0QF84_MYCA1 Tax_Id=243243 SubName: Full=Mycocerosic a... 2452 0.0 tr|B2HQ50|B2HQ50_MYCMM Tax_Id=216594 (pks5_1)SubName: Full=Polyk... 2432 0.0 tr|Q1B7A8|Q1B7A8_MYCSS Tax_Id=164756 SubName: Full=Acyl transfer... 2404 0.0 tr|A1UHR5|A1UHR5_MYCSK Tax_Id=189918 SubName: Full=Acyl transfer... 2404 0.0 tr|A3Q182|A3Q182_MYCSJ Tax_Id=164757 SubName: Full=Acyl transfer... 2402 0.0 tr|C1AMH5|C1AMH5_MYCBT Tax_Id=561275 (pks3)SubName: Full=Putativ... 2320 0.0 tr|A1KHX1|A1KHX1_MYCBP Tax_Id=410289 (pks3)SubName: Full=Probabl... 2320 0.0 tr|Q7U0G2|Q7U0G2_MYCBO Tax_Id=1765 (pks3)SubName: Full=PROBABLE ... 2317 0.0 tr|C6DUX7|C6DUX7_MYCTK Tax_Id=478434 SubName: Full=Polyketide be... 2317 0.0 tr|A5U1M9|A5U1M9_MYCTA Tax_Id=419947 (pks3)SubName: Full=Polyket... 2317 0.0 tr|Q8VK52|Q8VK52_MYCTU Tax_Id=1773 (mas-1)SubName: Full=Mycocero... 2317 0.0 tr|A5WLK9|A5WLK9_MYCTF Tax_Id=336982 SubName: Full=Polyketide be... 2317 0.0 tr|A4KGA7|A4KGA7_MYCTU Tax_Id=395095 SubName: Full=Polyketide be... 2317 0.0 tr|A0R1E8|A0R1E8_MYCS2 Tax_Id=246196 SubName: Full=Mycocerosic a... 2312 0.0 tr|Q49624|Q49624_MYCLE Tax_Id=1769 (pks3)SubName: Full=Mycoceros... 2306 0.0 tr|B8ZR93|B8ZR93_MYCLB Tax_Id=561304 (pks3)SubName: Full=Mycocer... 2306 0.0 tr|A0QCC7|A0QCC7_MYCA1 Tax_Id=243243 SubName: Full=Mycocerosic a... 2300 0.0 tr|Q73YT8|Q73YT8_MYCPA Tax_Id=1770 (pks5)SubName: Full=Pks5;[Myc... 2293 0.0 >tr|Q9CD78|Q9CD78_MYCLE Tax_Id=1769 (mas)SubName: Full=Putative mycocerosic synthase;[Mycobacterium leprae] Length = 2116 Score = 3940 bits (10218), Expect = 0.0 Identities = 2004/2116 (94%), Positives = 2004/2116 (94%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG Sbjct: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR Sbjct: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDAQVAVYQAALAVAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT Sbjct: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ Sbjct: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW Sbjct: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP Sbjct: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 SVFAVQVALATTMEQTYGVRPGAVIGHSM DAARVICRRSKLMNRV Sbjct: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSLEDAARVICRRSKLMNRV 660 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV Sbjct: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHSSQV MTPKVPYYSATLFDPRELPVCNGAYWVD Sbjct: 721 MAREVAVDVASHSSQVDPILDDLAAALADIAPMTPKVPYYSATLFDPRELPVCNGAYWVD 780 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP Sbjct: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV Sbjct: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEM Sbjct: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMALAAAVEVFG 960 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 IAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD Sbjct: 961 EAAEVRAIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQ SGTVLAEVA Sbjct: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQLGAAFAGLATAHTAEAESGTVLAEVA 1080 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR Sbjct: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 Query: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ Sbjct: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 Query: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV 1260 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV Sbjct: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV 1260 Query: 1261 VSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLF 1320 VSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLF Sbjct: 1261 VSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLF 1320 Query: 1321 VVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGS 1380 VVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGS Sbjct: 1321 VVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGS 1380 Query: 1381 EEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRV 1440 EEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRV Sbjct: 1381 EEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRV 1440 Query: 1441 PPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQIGD 1500 PPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDF HQIGD Sbjct: 1441 PPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFVGVVTAVGEGVTGHQIGD 1500 Query: 1501 RVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGDKV 1560 RVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQ WYGLNDLAGIKVGDKV Sbjct: 1501 RVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQAITAATAHATAWYGLNDLAGIKVGDKV 1560 Query: 1561 LIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRD 1620 LIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRD Sbjct: 1561 LIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRD 1620 Query: 1621 TDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLD 1680 TDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLD Sbjct: 1621 TDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLD 1680 Query: 1681 LALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLD 1740 LALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLD Sbjct: 1681 LALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLD 1740 Query: 1741 IPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQPNP 1800 IPRTGSRSVAVPPEQAPVYRRDGSYIIT FFASKLAEAGCGRIVLTARSQPNP Sbjct: 1741 IPRTGSRSVAVPPEQAPVYRRDGSYIITGGLGGLGLFFASKLAEAGCGRIVLTARSQPNP 1800 Query: 1801 KARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN 1860 KARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN Sbjct: 1801 KARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN 1860 Query: 1861 ITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLF 1920 ITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLF Sbjct: 1861 ITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLF 1920 Query: 1921 AHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIP 1980 AHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIP Sbjct: 1921 AHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIP 1980 Query: 1981 ILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVI 2040 ILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVI Sbjct: 1981 ILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVI 2040 Query: 2041 LRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAE 2100 LRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAE Sbjct: 2041 LRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAE 2100 Query: 2101 EEGVAAPAAMVSPETP 2116 EEGVAAPAAMVSPETP Sbjct: 2101 EEGVAAPAAMVSPETP 2116 >tr|B8ZTZ2|B8ZTZ2_MYCLB Tax_Id=561304 (mas)SubName: Full=Putative mycocerosic synthase;[Mycobacterium leprae] Length = 2116 Score = 3940 bits (10218), Expect = 0.0 Identities = 2004/2116 (94%), Positives = 2004/2116 (94%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG Sbjct: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR Sbjct: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDAQVAVYQAALAVAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT Sbjct: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ Sbjct: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW Sbjct: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP Sbjct: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 SVFAVQVALATTMEQTYGVRPGAVIGHSM DAARVICRRSKLMNRV Sbjct: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSLEDAARVICRRSKLMNRV 660 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV Sbjct: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHSSQV MTPKVPYYSATLFDPRELPVCNGAYWVD Sbjct: 721 MAREVAVDVASHSSQVDPILDDLAAALADIAPMTPKVPYYSATLFDPRELPVCNGAYWVD 780 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP Sbjct: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV Sbjct: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEM Sbjct: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMALAAAVEVFG 960 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 IAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD Sbjct: 961 EAAEVRAIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQ SGTVLAEVA Sbjct: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQLGAAFAGLATAHTAEAESGTVLAEVA 1080 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR Sbjct: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 Query: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ Sbjct: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 Query: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV 1260 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV Sbjct: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV 1260 Query: 1261 VSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLF 1320 VSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLF Sbjct: 1261 VSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLF 1320 Query: 1321 VVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGS 1380 VVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGS Sbjct: 1321 VVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGS 1380 Query: 1381 EEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRV 1440 EEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRV Sbjct: 1381 EEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRV 1440 Query: 1441 PPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQIGD 1500 PPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDF HQIGD Sbjct: 1441 PPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFVGVVTAVGEGVTGHQIGD 1500 Query: 1501 RVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGDKV 1560 RVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQ WYGLNDLAGIKVGDKV Sbjct: 1501 RVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQAITAATAHATAWYGLNDLAGIKVGDKV 1560 Query: 1561 LIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRD 1620 LIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRD Sbjct: 1561 LIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRD 1620 Query: 1621 TDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLD 1680 TDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLD Sbjct: 1621 TDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLD 1680 Query: 1681 LALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLD 1740 LALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLD Sbjct: 1681 LALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLD 1740 Query: 1741 IPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQPNP 1800 IPRTGSRSVAVPPEQAPVYRRDGSYIIT FFASKLAEAGCGRIVLTARSQPNP Sbjct: 1741 IPRTGSRSVAVPPEQAPVYRRDGSYIITGGLGGLGLFFASKLAEAGCGRIVLTARSQPNP 1800 Query: 1801 KARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN 1860 KARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN Sbjct: 1801 KARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN 1860 Query: 1861 ITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLF 1920 ITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLF Sbjct: 1861 ITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLF 1920 Query: 1921 AHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIP 1980 AHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIP Sbjct: 1921 AHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIP 1980 Query: 1981 ILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVI 2040 ILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVI Sbjct: 1981 ILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVI 2040 Query: 2041 LRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAE 2100 LRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAE Sbjct: 2041 LRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAE 2100 Query: 2101 EEGVAAPAAMVSPETP 2116 EEGVAAPAAMVSPETP Sbjct: 2101 EEGVAAPAAMVSPETP 2116 >tr|P96291|P96291_MYCTU Tax_Id=1773 (mas)SubName: Full=Mycocerosic acid synthase; SubName: Full=PROBABLE MULTIFUNCTIONAL MYCOCEROSIC ACID SYNTHASE MEMBRANE-ASSOCIATED MAS;[Mycobacterium tuberculosis] Length = 2111 Score = 3453 bits (8954), Expect = 0.0 Identities = 1757/2118 (82%), Positives = 1861/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHASVAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHASVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >tr|C6DWB4|C6DWB4_MYCTK Tax_Id=478434 SubName: Full=Multifunctional mycocerosic acid synthase membrane-associated mas;[Mycobacterium tuberculosis] Length = 2111 Score = 3453 bits (8954), Expect = 0.0 Identities = 1757/2118 (82%), Positives = 1861/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHASVAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHASVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >tr|A5U6U7|A5U6U7_MYCTA Tax_Id=419947 (mas)SubName: Full=Multifunctional mycocerosic acid synthase membrane-associated Mas;[Mycobacterium tuberculosis] Length = 2111 Score = 3453 bits (8954), Expect = 0.0 Identities = 1757/2118 (82%), Positives = 1861/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHASVAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHASVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >tr|A5WRJ2|A5WRJ2_MYCTF Tax_Id=336982 SubName: Full=Multi-functional membrane-associated mycocerosic acid synthase mas;[Mycobacterium tuberculosis] Length = 2111 Score = 3453 bits (8954), Expect = 0.0 Identities = 1757/2118 (82%), Positives = 1861/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHASVAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHASVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >tr|A4KKK0|A4KKK0_MYCTU Tax_Id=395095 SubName: Full=Multifunctional mycocerosic acid synthase membrane-associated mas;[Mycobacterium tuberculosis str. Haarlem] Length = 2111 Score = 3453 bits (8954), Expect = 0.0 Identities = 1757/2118 (82%), Positives = 1861/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHASVAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHASVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >tr|A2VLR6|A2VLR6_MYCTU Tax_Id=348776 SubName: Full=Multifunctional mycocerosic acid synthase membrane-associated mas;[Mycobacterium tuberculosis C] Length = 2111 Score = 3453 bits (8954), Expect = 0.0 Identities = 1757/2118 (82%), Positives = 1861/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHASVAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHASVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >sp|Q02251|MCAS_MYCBO Tax_Id=1765 (mas)RecName: Full=Mycocerosic acid synthase; EC=2.3.1.111;[Mycobacterium bovis] Length = 2111 Score = 3451 bits (8949), Expect = 0.0 Identities = 1756/2118 (82%), Positives = 1860/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHA VAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHACVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >tr|C1AG56|C1AG56_MYCBT Tax_Id=561275 (mas)SubName: Full=Putative multifunctional mycocerosic acid synthase membrane-associated;[Mycobacterium bovis] Length = 2111 Score = 3451 bits (8949), Expect = 0.0 Identities = 1756/2118 (82%), Positives = 1860/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHA VAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHACVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >tr|A1KMT5|A1KMT5_MYCBP Tax_Id=410289 (mas)SubName: Full=Probable multifunctional mycocerosic acid synthase membrane-associated mas;[Mycobacterium bovis] Length = 2111 Score = 3451 bits (8949), Expect = 0.0 Identities = 1756/2118 (82%), Positives = 1860/2118 (87%), Gaps = 17/2118 (0%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ME+ VTP+AVIGMGCRLPGGINSPDKLWESLLRGD+LVTE+PPDRWD DD+YDPEPGVPG Sbjct: 1 MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIE GLDPASLAGSS Sbjct: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 TAVFTGLTHEDYLVLTT AGGLASPYVVTGLNNSVASGRI+HTLGLHGPAMTFDTACSSG Sbjct: 121 TAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 LMAVHLACRSLHDGE+DLALAGGCAVLLEPHA VAASAQGMLSSTGRC SF ADADGFVR Sbjct: 181 LMAVHLACRSLHDGEADLALAGGCAVLLEPHACVAASAQGMLSSTGRCHSFDADADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDGNRIFA++ GTATNQDG TETL MPSED Sbjct: 241 SEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +PET+GVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK Sbjct: 301 VQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSLR+G+VPPLLHF+RL D+L+++ETGLFVPQ VTPWP G +TPKRVAVSSFGMSGT Sbjct: 361 AILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGT 420 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH IVEEAP+EA AP E+SPG DA VG +LFMLSSTS ALR+TARQLATWVEEHQ Sbjct: 421 NVHAIVEEAPAEASAP---ESSPG--DAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQ 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D V SDLAYTLARGRAHRPVRTAVVAA+LPELVEGL E+ADGDALYDA VGHGDRGPVW Sbjct: 476 DCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVW 535 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG QLLA+EPVFAATI KLEPVIAAES FSVTEAITA +TVTGIDKVQP Sbjct: 536 VFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQP 595 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQVALA TMEQTYGVRPGAV+GHSM DAARVICRRSKLM R+ Sbjct: 596 AVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRI 655 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAMGSVELPAKQVNSELMARGIDDVV+SVVASPQSTVIGG ++TVRDLIA+WEQRDV Sbjct: 656 AGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDV 715 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV MTPKVPYYSATLFDPRE PVC+GAYWVD Sbjct: 716 MAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVD 775 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQT R+LDMSVAALAGMRREQ +P Sbjct: 776 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLP 835 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGLL +LH AGAALD++ALYPAGRL+DAPLP WTH RLFID DGQEQRAQGACT+TV Sbjct: 836 HGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITV 895 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH+WQGDVGT+ LSWL+DHQVHNVAALPGAAYCEM Sbjct: 896 HPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFG 955 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQMLLL +TPIDA+AS+DAPGV+NF V+ N+DGE R+ATA L AAEDD Sbjct: 956 EAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDD 1015 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 CPPP YDI ALL+AHP++VNGT +RESFAERGV + TVLAEVA Sbjct: 1016 CPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVA 1075 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LPASIRFQQ +Y+IHPALLDACFQSVGAGV A + GLLLPLGVRSLR Y PTRNAR Sbjct: 1076 LPASIRFQQGAYRIHPALLDACFQSVGAGVQAGT--ATGGLLLPLGVRSLRAYGPTRNAR 1133 Query: 1141 YCYTRLTKI---EPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTI 1197 YCYTRLTK RGGEADLDVLDEHG VLLAVRGL MGTGT+ER E DR +SERLLT+ Sbjct: 1134 YCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTL 1193 Query: 1198 GWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD 1257 GWQQR LPE E GSWLLIDT NA PDM ASTLTDALKS+G QGTEC +LSW +QD Sbjct: 1194 GWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQD 1253 Query: 1258 DPVVSR---ERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 P + E+LG QLRGRDGVVI+ GPR G PDE SLLA REQVRHLVRI RELAE EG Sbjct: 1254 TPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEG 1313 Query: 1315 ELPRLFVVTRQAQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVER 1371 ELPRLFVVTRQAQIV+ SG+ ANLEQAGLRGLLRVISSEHPMLRTTL+DVDEHTDVER Sbjct: 1314 ELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVER 1373 Query: 1372 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQS 1431 VAQQLLSGSEEDETAWRNGDWYVARL PSPL HE+RRT VL+P+HDG+RV VR+PGDLQ+ Sbjct: 1374 VAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQT 1433 Query: 1432 LELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXX 1491 LE VASDRVPPGPGQ+EVAVSMSSINFADVLIAFGRFPIIDDR+PQLGMDF Sbjct: 1434 LEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGE 1493 Query: 1492 XXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDL 1551 HQ+GDRVGGFSEGGCWRTFLTCDANLAVTLP GLTDEQ WYGLNDL Sbjct: 1494 GVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDL 1553 Query: 1552 AGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSV 1611 A IK GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNP KRAML D+G+EHVYDSRSV Sbjct: 1554 AQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSV 1613 Query: 1612 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR 1671 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTRLGLFPFR Sbjct: 1614 EFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR 1673 Query: 1672 RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNA 1731 RGLTFYYLDLALMSVTQPDRVRELLATVF LTADGVLTAP+CTHYPL +AA+AIRAMSNA Sbjct: 1674 RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNA 1733 Query: 1732 EHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIV 1791 EHTGKLVLD+PR+G RSVAV PEQAP+YRRDGSYIIT FFASKLA AGCGRIV Sbjct: 1734 EHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIV 1793 Query: 1792 LTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAA 1851 LTARSQPNPKARQTIE L AAGADIVVECGNIAEP TADRLV+AATATGLPLRGVLHSAA Sbjct: 1794 LTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAA 1853 Query: 1852 VVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYA 1911 VVEDATLTNITDELIDRDWSPKV+GSWNLH AT+GQPLDWFCLFSSGAALLGSPGQGAYA Sbjct: 1854 VVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYA 1913 Query: 1912 AANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRY 1971 AANSWVD+FAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITP+EGAYAFE LVR+ Sbjct: 1914 AANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRH 1973 Query: 1972 DRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRR 2031 DR YSGYIPILGAPWL DLVRRSPW EMF+S GQ SRGPSKFRMELL+LPQDEW+GRLRR Sbjct: 1974 DRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRR 2033 Query: 2032 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALA 2091 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTH+E+ETGIRLTPKVIATNNTARALA Sbjct: 2034 LLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALA 2093 Query: 2092 QYLADTLAEEEGVAAPAA 2109 QYLADTLAEE+ AAPAA Sbjct: 2094 QYLADTLAEEQ-AAAPAA 2110 >tr|B2HIM2|B2HIM2_MYCMM Tax_Id=216594 (mas)SubName: Full=Multifunctional mycocerosic acid synthase membrane-associated Mas;[Mycobacterium marinum] Length = 2099 Score = 3006 bits (7793), Expect = 0.0 Identities = 1515/2115 (71%), Positives = 1726/2115 (81%), Gaps = 23/2115 (1%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 M+ TP+A+IGMGCRLPGG++SP+KLWESLLRGD+LV+E+PPDRWDVDD+YDPEPGVPG Sbjct: 1 MQKPATPVAIIGMGCRLPGGVDSPEKLWESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 R+VSRWGGF+DDVAGFDAEFFG+SEREATSIDPQ R LLET+WEAIE GLDPASL+GSS Sbjct: 61 RTVSRWGGFIDDVAGFDAEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 T VF GL+HEDYLV + AG LA PY TGL NSVASGRI+HTLGLHGPAMT DTACSSG Sbjct: 121 TGVFVGLSHEDYLVRSVLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTVDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 L+ VHLACRSLH+GESDLALAGGCA+LLEP+ SV+ S+QGMLS TGRC +F DADGFVR Sbjct: 181 LLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLSPTGRCHAFDVDADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCA+V+LKRL DAL DG+RI A++ GTA NQDG +ETL+MPSE Sbjct: 241 SEGCAVVVLKRLSDALADGDRILAVVRGTAANQDGRSETLLMPSETAQVAVYREALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAG-TPCALGSAKSNMGHSTASAGTVGLI 359 +P ++G VE HGTGTP+GDPIEYRSLA+VYG+G + C LGS K+N+GHS ++AGTVGLI Sbjct: 301 VDPASVGAVEVHGTGTPVGDPIEYRSLAQVYGSGGSRCMLGSVKTNIGHSESAAGTVGLI 360 Query: 360 KAILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSG 419 KA LSL +G+VPP++H RL D+L EIETGL+VP E+TPWP P+R+AVSSFGMSG Sbjct: 361 KATLSLGHGVVPPMVHHTRLPDELAEIETGLYVPHEITPWPED--QGPRRIAVSSFGMSG 418 Query: 420 TNVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWV--- 476 TNVH I+EE P+ A A D PG LF LSSTS LR+TAR+LA WV Sbjct: 419 TNVHAILEEPPTPAPARDQAPAEPGMASPL----LFALSSTSADGLRQTARELAEWVGSR 474 Query: 477 EEHQDSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDR 536 + DS DLAYTLAR RAHRPVRTAVVAA LPELVEGL E+A+GD +Y+A VG GDR Sbjct: 475 ADSADSTEAVDLAYTLARRRAHRPVRTAVVAASLPELVEGLQEVAEGDLMYEAAVGRGDR 534 Query: 537 GPVWVFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGID 596 GPVWVFSGQGSQWA+MG LLANEPVFAAT+ +EP+IA ES FSVTEA+TAPE VTGID Sbjct: 535 GPVWVFSGQGSQWAAMGADLLANEPVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTGID 594 Query: 597 KVQPSVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKL 656 KVQP++FA+QVALA TME+TYGVRPGAVIGHS+ D ARVI RRSKL Sbjct: 595 KVQPTLFAMQVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGARVISRRSKL 654 Query: 657 MNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWE 716 M R++G+GAM SVELPAKQVNSELMARGIDDV ++VVASPQSTV+GGAT+TVRDL+A+WE Sbjct: 655 MLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQSTVVGGATDTVRDLVARWE 714 Query: 717 QRDVMAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGA 776 QR+VMAREVAVDVASHS QV PKVPYYSATLFDPRE P C+ A Sbjct: 715 QREVMAREVAVDVASHSPQVDPILEDLATALADIVPSDPKVPYYSATLFDPRERPTCDAA 774 Query: 777 YWVDNLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRRE 836 YWVDNLRNTVQFAAAVQAA+EDG+RVFAELSPHPLLTHAV+Q AR+LDMS AALAGMRRE Sbjct: 775 YWVDNLRNTVQFAAAVQAALEDGFRVFAELSPHPLLTHAVDQNARSLDMSAAALAGMRRE 834 Query: 837 QSMPYGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGAC 896 Q +P+GLRGLL D+HSAGAA+DF+ LYPAGRL++APLP WTH R F+D +GQ+ +AQGAC Sbjct: 835 QPLPHGLRGLLTDVHSAGAAVDFSVLYPAGRLVNAPLPAWTHRRFFVDGEGQDSKAQGAC 894 Query: 897 TVTVHPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXX 956 +VTVHPLLG+HVRL E+PERH+WQ DVGT LSWL+DHQV NVAALPGAAYCEM Sbjct: 895 SVTVHPLLGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAAYCEMALAAAG 954 Query: 957 XXXXXXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHA 1016 +AFEQMLLL ETPIDA+AS+D+PG NFVVQ + DGE R+ATA L A Sbjct: 955 EVFGEAFEVRDLAFEQMLLLDEETPIDAVASLDSPGAANFVVQTHVDGETTRHATAALRA 1014 Query: 1017 AEDDCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVL 1076 ++D+ PPAYDIAALL AHP SVNG +LRE+F ERG+Q GTVL Sbjct: 1015 SDDESVPPAYDIAALLAAHPVSVNGAELREAFVERGIQHGPAFSGLAIARTAETEGGTVL 1074 Query: 1077 AEVALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPT 1136 AEVALPASIRFQQ +Y +HPALLDACFQSV AGV +T G GLLLPLGVRSLR Y PT Sbjct: 1075 AEVALPASIRFQQGAYGVHPALLDACFQSVAAGVKSTGGG---GLLLPLGVRSLRAYGPT 1131 Query: 1137 RNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLT 1196 RNA+YCYTR+TK + GGEADL++LDE G VLLAVRGL +GTGT+E GE DR LSERLLT Sbjct: 1132 RNAQYCYTRVTKADANGGEADLELLDEQGCVLLAVRGLRLGTGTSESGERDRVLSERLLT 1191 Query: 1197 IGWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQ 1256 + WQQR LPE + E GSWLLI +AS D+ A+ L DALKS QG EC ++ W Q Sbjct: 1192 LEWQQRQLPEVLDEETGSWLLI---SASDGEDLMATMLADALKS---QGAECASMVWSAQ 1245 Query: 1257 DDPVVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 DD E+LG QLR R GVVI+CGPR+G DEQSLL REQVRHLVRI RELAELEG Sbjct: 1246 DDLAGGIEKLGAQLRARTNKGVVIVCGPRSGDADEQSLLQGREQVRHLVRITRELAELEG 1305 Query: 1315 ELPRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQ 1374 ELPRLFVVTRQAQ V+ D NLEQAGLRGLLRVI SEHP+L+TT VDVDE T E++AQ Sbjct: 1306 ELPRLFVVTRQAQRVRPEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDVDESTQAEQLAQ 1365 Query: 1375 QLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLEL 1434 QLL GSEEDETAWR G+WYVARL P PLS ++R+T +++ E D +R+ +R PGDLQ+LEL Sbjct: 1366 QLLGGSEEDETAWRGGEWYVARLFPGPLSADERQTTIVDHERDNMRLQIRTPGDLQTLEL 1425 Query: 1435 VASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXX 1494 A DRVPPGPGQ+EVAV+MSSINFADVLIAFGR+P ++ R P+ G DF Sbjct: 1426 AACDRVPPGPGQIEVAVTMSSINFADVLIAFGRYPSLEGRLPETGTDFVGVVTAVGEGVT 1485 Query: 1495 XHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGI 1554 HQ+GDRVGGFS+ GCWR++LTCDANLAVTLP+GL+DE WYGLNDLAGI Sbjct: 1486 DHQVGDRVGGFSKDGCWRSYLTCDANLAVTLPAGLSDEHAAASSTAHATAWYGLNDLAGI 1545 Query: 1555 KVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFA 1614 K GD+VLIHSATGGVGQAAI+IARA GA+IFATAGN +R +L+D+GIEHVYDSRS+EFA Sbjct: 1546 KAGDRVLIHSATGGVGQAAIAIARAAGAQIFATAGNAERRQLLNDMGIEHVYDSRSIEFA 1605 Query: 1615 EQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGL 1674 +QIRRDT+GYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTR+GL+PFRRGL Sbjct: 1606 DQIRRDTNGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRMGLYPFRRGL 1665 Query: 1675 TFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHT 1734 TFYY+DL LMSV QP+RVRELL+TV+NLTA+GVL+APECTHYPL +AA AIR MSNA HT Sbjct: 1666 TFYYVDLGLMSVIQPERVRELLSTVYNLTAEGVLSAPECTHYPLAEAAEAIRTMSNAAHT 1725 Query: 1735 GKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTA 1794 GKL+LD+PR+G R V VPPEQ V+R DGSYIIT FFASK+A AGCGRIVLTA Sbjct: 1726 GKLLLDMPRSGRRGVVVPPEQVEVFRGDGSYIITGGLGGLGLFFASKMAAAGCGRIVLTA 1785 Query: 1795 RSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVE 1854 RSQPNPK+RQ IERL A GADIVVECGNIAEP TADRLV+AATATGLPLRGVLH+AAVVE Sbjct: 1786 RSQPNPKSRQAIERLRANGADIVVECGNIAEPETADRLVSAATATGLPLRGVLHAAAVVE 1845 Query: 1855 DATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAAN 1914 DATL+NITDELIDRDWSPKVYGSWNLH A+ GQPLDWFCLFSSGAAL+GSPGQGAYAAAN Sbjct: 1846 DATLSNITDELIDRDWSPKVYGSWNLHRASTGQPLDWFCLFSSGAALMGSPGQGAYAAAN 1905 Query: 1915 SWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRP 1974 SWVD FAHWRRAQGLPV AI WGAWGEVGRATFLAEGGEIMI PDEG YAFE ++R+ R Sbjct: 1906 SWVDAFAHWRRAQGLPVCAIGWGAWGEVGRATFLAEGGEIMIAPDEGMYAFEQMLRHART 1965 Query: 1975 YSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLV 2034 Y+GYIPI+GAPWL DLVRRSPWAEMF S+GQ +RGPSKF EL LPQ+EW+GRLRRL+ Sbjct: 1966 YTGYIPIIGAPWLADLVRRSPWAEMFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIA 2025 Query: 2035 EQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYL 2094 EQASVILRRT+DADR F+EYGLDSLGMLEMRTHIE+ETG+RL+PKVIA++NTARAL+Q+L Sbjct: 2026 EQASVILRRTVDADRPFVEYGLDSLGMLEMRTHIETETGVRLSPKVIASHNTARALSQHL 2085 Query: 2095 ADTLAEEEGVAAPAA 2109 ADTLAEEE A PAA Sbjct: 2086 ADTLAEEE--AQPAA 2098 >tr|A0PQ30|A0PQ30_MYCUA Tax_Id=362242 (mas)SubName: Full=Multifunctional mycocerosic acid synthase membrane-associated Mas;[Mycobacterium ulcerans] Length = 2099 Score = 2999 bits (7776), Expect = 0.0 Identities = 1513/2115 (71%), Positives = 1724/2115 (81%), Gaps = 23/2115 (1%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 M+ S TP+A+IGMGCRLPGG++SP+KLWESLLRGD+LV+E+PPDRWDVDD+YDPEPGVPG Sbjct: 1 MQKSATPVAIIGMGCRLPGGVDSPEKLWESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPG 60 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 R+VSRWGGF+DDVAGFDAEFFG+SEREATSIDPQ R LLET+WEAIE GLDPASL+GSS Sbjct: 61 RTVSRWGGFIDDVAGFDAEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSS 120 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 T VF GL+HEDYLV + AG LA PY TGL NSVASGRI+HTLGLHGPAMT DTACSSG Sbjct: 121 TGVFVGLSHEDYLVRSVLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTVDTACSSG 180 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 L+ VHLACRSLH+GESDLALAGGCA+LLEP+ SV+ S+QGMLS TGRC +F DADGFVR Sbjct: 181 LLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLSPTGRCHAFDVDADGFVR 240 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCA+V+LKRL DAL DG+RI A++ GTA NQDG +ETL+MPSE Sbjct: 241 SEGCAVVVLKRLSDALADGDRILAVVRGTAANQDGRSETLLMPSETAQVAVYREALAAAG 300 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAG-TPCALGSAKSNMGHSTASAGTVGLI 359 + ++G VE HGTGTP+GDPIEYRSLA+VYG+G + C LGS K+N+GHS ++AGTVGLI Sbjct: 301 VDAASVGAVEVHGTGTPVGDPIEYRSLAQVYGSGGSRCMLGSVKTNIGHSESAAGTVGLI 360 Query: 360 KAILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSG 419 KA LSL +G+VPP++H RL D+L EIETGL+VP E+TPWP P+R+AVSSFGMSG Sbjct: 361 KATLSLGHGVVPPMVHHTRLPDELAEIETGLYVPHEITPWPED--QGPRRIAVSSFGMSG 418 Query: 420 TNVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWV--- 476 TNVH I+EE P+ A A D PG LF LSSTS LR+TAR+LA WV Sbjct: 419 TNVHAILEEPPTPAPARDQASAEPGMASPL----LFALSSTSADGLRQTARELAEWVGSR 474 Query: 477 EEHQDSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDR 536 + DS DLAYTLAR RAHRPVRTAVVAA LPELVEGL E+A+GD +Y+A VG GDR Sbjct: 475 ADSADSTEAVDLAYTLARRRAHRPVRTAVVAASLPELVEGLQEVAEGDLVYEAAVGRGDR 534 Query: 537 GPVWVFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGID 596 GPVWVFSGQGSQWA+MG LLANEPVFAAT+ +EP+IA ES FSVTEA+TAPE VTGID Sbjct: 535 GPVWVFSGQGSQWAAMGADLLANEPVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTGID 594 Query: 597 KVQPSVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKL 656 KVQP++FA+QVALA TME+TYGVRPGAVIGHS+ D ARVI RRSKL Sbjct: 595 KVQPTLFAMQVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGARVISRRSKL 654 Query: 657 MNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWE 716 M R++G+GAM SVELPAKQVNSELMARGIDDV ++VVASPQSTV+GGAT+TVRDL+A+WE Sbjct: 655 MLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQSTVVGGATDTVRDLVARWE 714 Query: 717 QRDVMAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGA 776 QR+VMAREVAVDVASHS QV PKVPYYSATLFDPRE P C+ A Sbjct: 715 QREVMAREVAVDVASHSPQVDPILEDLATALADIVPSDPKVPYYSATLFDPRERPTCDAA 774 Query: 777 YWVDNLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRRE 836 YWVDNLRNTVQFAAAVQAA+EDG+RVFAELSPHPLLTHAV+Q AR+LDMS A LAGMRRE Sbjct: 775 YWVDNLRNTVQFAAAVQAALEDGFRVFAELSPHPLLTHAVDQNARSLDMSAAVLAGMRRE 834 Query: 837 QSMPYGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGAC 896 Q +P+GLRGLL D+HSAGAA+DF+ LYPAGRL++AP P WTH R F+D +GQ+ +AQGAC Sbjct: 835 QPLPHGLRGLLTDVHSAGAAVDFSVLYPAGRLVNAPPPAWTHRRFFVDGEGQDSKAQGAC 894 Query: 897 TVTVHPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXX 956 +VTVHPLLG+HVRL E+PERH+WQ DVGT LSWL+DHQV NVAALPGAAYCEM Sbjct: 895 SVTVHPLLGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAAYCEMALAAAG 954 Query: 957 XXXXXXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHA 1016 +AFEQMLLL ETPIDA+AS+D+PG NFVVQ + DGE R+ATA L A Sbjct: 955 EVFGEAFEVRDLAFEQMLLLDEETPIDAVASLDSPGAANFVVQTHVDGETTRHATAALRA 1014 Query: 1017 AEDDCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVL 1076 ++D+ PPAYDIAALL AHP SVNG +LRE+F ERG+Q GTVL Sbjct: 1015 SDDESVPPAYDIAALLAAHPVSVNGAELREAFVERGIQHGPAFSGLAIARTAETEGGTVL 1074 Query: 1077 AEVALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPT 1136 AEVALPASIRFQQ +Y +HPALLDACFQSV AGV +T G GLLLPLGVRSLR Y PT Sbjct: 1075 AEVALPASIRFQQGAYGVHPALLDACFQSVAAGVKSTGGG---GLLLPLGVRSLRAYGPT 1131 Query: 1137 RNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLT 1196 RNA+YCYTR+TK + GGEADL++LDE G VLLAVRGL +GTGT+E GE DR LSERLLT Sbjct: 1132 RNAQYCYTRVTKADANGGEADLELLDEQGCVLLAVRGLRLGTGTSESGERDRVLSERLLT 1191 Query: 1197 IGWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQ 1256 + WQQR LPE + E GSWLLI +AS D+ A+TL DALKS QG EC ++ W Q Sbjct: 1192 LEWQQRQLPEVLDEETGSWLLI---SASDGEDLMATTLADALKS---QGAECASMVWSAQ 1245 Query: 1257 DDPVVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEG 1314 DD E+LG QLR R GVVI+CGPR+G DEQSLL REQVRHLVRI R LAELEG Sbjct: 1246 DDLAGGIEKLGAQLRARTNKGVVIVCGPRSGDADEQSLLQGREQVRHLVRITRGLAELEG 1305 Query: 1315 ELPRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQ 1374 ELPRLFVVTRQAQ V+ D NLEQAGLRGLLRVI SEHP+L+TT VDVDE T E++AQ Sbjct: 1306 ELPRLFVVTRQAQRVRPEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDVDESTQAEQLAQ 1365 Query: 1375 QLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLEL 1434 QLL GSEEDETAWR G+WYVARL P PLS ++R+T V++ E D +R+ +R PGDLQ+LEL Sbjct: 1366 QLLGGSEEDETAWRGGEWYVARLFPGPLSADERQTTVVDHERDNMRLQIRTPGDLQTLEL 1425 Query: 1435 VASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXX 1494 A DRVPPGPGQ+EVAV+MSSINFADVLIAFGR+P ++ R P+ G DF Sbjct: 1426 AACDRVPPGPGQIEVAVTMSSINFADVLIAFGRYPSLEGRLPETGTDFVGVVTAVGEGVT 1485 Query: 1495 XHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGI 1554 HQ+GDRVGGFS+ GCWR++LTCDANLAVTLP+GL+DE WYGLNDLAGI Sbjct: 1486 DHQVGDRVGGFSKDGCWRSYLTCDANLAVTLPAGLSDEHAAASSTAHATAWYGLNDLAGI 1545 Query: 1555 KVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFA 1614 K GD+VLIHSATGGVGQAAI+IARA GA+IFATAGN +R +++D+GIEHVYDSRS+EFA Sbjct: 1546 KAGDRVLIHSATGGVGQAAIAIARAAGAQIFATAGNAERRQLVNDMGIEHVYDSRSIEFA 1605 Query: 1615 EQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGL 1674 +QIRRDT+GYGVDIVLNSLTGAAQRAGLELL FGGRFVEIGKADVYGNTR+GL+PFRRGL Sbjct: 1606 DQIRRDTNGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRMGLYPFRRGL 1665 Query: 1675 TFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHT 1734 TFYY+DL LMSV QP+RVRELL+TV+NLTA+GVL+APECTHYPL +AA AIR MSNA HT Sbjct: 1666 TFYYVDLGLMSVIQPERVRELLSTVYNLTAEGVLSAPECTHYPLAEAAEAIRTMSNAAHT 1725 Query: 1735 GKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTA 1794 GKL+LD+PR+G R V VPPEQ V+R DGSYIIT FFASK+A AGCGRIVLTA Sbjct: 1726 GKLLLDMPRSGRRGVVVPPEQVEVFRGDGSYIITGGLGGLGLFFASKMAAAGCGRIVLTA 1785 Query: 1795 RSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVE 1854 RSQPNPK+RQ IERL A GADIVVECGNIAEP TADRLV+AATATGLPLRGVLH+AAVVE Sbjct: 1786 RSQPNPKSRQAIERLRANGADIVVECGNIAEPETADRLVSAATATGLPLRGVLHAAAVVE 1845 Query: 1855 DATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAAN 1914 DATL+NITDELIDRDWSPKVYGSWNLH A+ GQPLDWFCLFSSGAAL+GSPGQGAYAAAN Sbjct: 1846 DATLSNITDELIDRDWSPKVYGSWNLHRASTGQPLDWFCLFSSGAALMGSPGQGAYAAAN 1905 Query: 1915 SWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRP 1974 SWVD FAHWRRAQGLPV AI WGAWGEVGRATFLAEGGEIMI PDEG YAFE ++R+ R Sbjct: 1906 SWVDAFAHWRRAQGLPVCAIGWGAWGEVGRATFLAEGGEIMIAPDEGMYAFEQMLRHART 1965 Query: 1975 YSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLV 2034 Y+GYIPI+GAPWL DLVRRSPWAEMF S+GQ +RGPSKF EL LPQ+EW+GRLRRL+ Sbjct: 1966 YTGYIPIIGAPWLADLVRRSPWAEMFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIA 2025 Query: 2035 EQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYL 2094 EQASVILRRT+DADR F+EYGLDSLGMLEMRTHIE+ETG+RL+PKVIA++NTARAL+Q+L Sbjct: 2026 EQASVILRRTVDADRPFVEYGLDSLGMLEMRTHIETETGVRLSPKVIASHNTARALSQHL 2085 Query: 2095 ADTLAEEEGVAAPAA 2109 ADTLAEEE A PAA Sbjct: 2086 ADTLAEEE--AQPAA 2098 >tr|B2HQ46|B2HQ46_MYCMM Tax_Id=216594 (pks5)SubName: Full=Probable polyketide synthase Pks5;[Mycobacterium marinum] Length = 2090 Score = 2497 bits (6471), Expect = 0.0 Identities = 1280/2105 (60%), Positives = 1533/2105 (72%), Gaps = 20/2105 (0%) Query: 5 VTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVS 64 +TP+AVIGM CRLPGGI SP++LWE+LLRGD+LVTE+P DRWD D++YDPEPGVPGR+V Sbjct: 1 MTPVAVIGMACRLPGGIGSPEELWEALLRGDDLVTEIPADRWDADEYYDPEPGVPGRTVC 60 Query: 65 RWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVF 124 +WG FLD+V FD EFFGI+E+EA +IDPQ R+LLET+WEA+E GGL P +A S T VF Sbjct: 61 KWGAFLDNVGDFDPEFFGITEKEAIAIDPQHRMLLETAWEAMEHGGLTPEQMAESLTGVF 120 Query: 125 TGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMAV 184 GL H DY + A PY TG N+ ASGRIS+ + LHGPA+T DTACSS L A Sbjct: 121 VGLNHGDYQFVHVDANTFDGPYGNTGTNSCFASGRISYAMRLHGPAVTVDTACSSSLYAT 180 Query: 185 HLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEGC 244 HLAC SL +GESDLA A G V+LEP + SAQ MLS TG C +F DADGFV EG Sbjct: 181 HLACNSLSEGESDLAFAAGVYVMLEPRRFASGSAQNMLSPTGHCHAFDVDADGFVSGEGS 240 Query: 245 AMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEPE 304 ++LLKRL DA RDG+RI A++ GTA NQDG T + PS + + Sbjct: 241 VVLLLKRLADAQRDGDRILAVMRGTAANQDGHTVNIATPSVEAQSAVYRAALATAGVDGA 300 Query: 305 TIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAILS 364 ++G+VEAHGTGTP+GDPIE+ SLARVYG PCAL SAK N GH A AG +GL+KAIL+ Sbjct: 301 SVGLVEAHGTGTPVGDPIEFESLARVYGIDRPCALTSAKPNFGHMQAGAGVLGLMKAILA 360 Query: 365 LRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVHV 424 L++G++PP +HF RL D++ +I++GLFVPQE+T WP G T + AVSS+G+SGTNVH Sbjct: 361 LQHGVIPPNIHFSRLPDEMAQIKSGLFVPQEITQWPTNGEQT-RTAAVSSYGISGTNVHA 419 Query: 425 IVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDSVV 484 I+E+AP E D SP A G +F LS+TS LR+TA++LA WV+ + Sbjct: 420 ILEQAP-ETATHDAEPVSP----AIEGALIFPLSATSADGLRQTAKRLADWVDAQGPELA 474 Query: 485 LSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVFSG 544 SDLAYTLAR R HRPVRTAV+A ++ EL GL EIAD + Y A VG DRGPVWVFSG Sbjct: 475 TSDLAYTLARRRGHRPVRTAVLADNVSELSAGLHEIADDETPYQAAVGRDDRGPVWVFSG 534 Query: 545 QGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSVFA 604 QGSQW +MG LLANEPVFAAT+ +LEP+IAAES FSVTEA+TA ETVTGID+VQP++F Sbjct: 535 QGSQWKAMGADLLANEPVFAATVAELEPLIAAESGFSVTEAMTAIETVTGIDRVQPTIFT 594 Query: 605 VQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAGSG 664 +QVALA TM+ +YGVRPGA+IGHS+ D A+VICRRS+LM R++GSG Sbjct: 595 MQVALAATMK-SYGVRPGAIIGHSLGESAAAVAAGALSLEDGAKVICRRSRLMTRISGSG 653 Query: 665 AMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMARE 724 AM SVELPA+QV SELMARGI+DVV++VVASPQSTVIGGAT+TVR+L+A WEQR+VMARE Sbjct: 654 AMASVELPAQQVLSELMARGINDVVVAVVASPQSTVIGGATDTVRELVAAWEQREVMARE 713 Query: 725 VAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNLRN 784 VAVDVASHS QV +TP+VPYYSATLFDPRE P C+G+YWVDNLR+ Sbjct: 714 VAVDVASHSPQVDPILDDLYDVLADLEPLTPEVPYYSATLFDPREEPYCDGSYWVDNLRH 773 Query: 785 TVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLR 844 TV+F AAVQAA+EDGYRVFAEL+PHPLLT AVE+TA LDM VAALAGMRREQ +P+GLR Sbjct: 774 TVRFGAAVQAALEDGYRVFAELAPHPLLTRAVEKTAEGLDMPVAALAGMRREQPLPHGLR 833 Query: 845 GLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHPLL 904 GLLADLHSAGAA+DF+ LYPAG L+DAPLP WTH L ++ GQ+ +AQG +V VHPLL Sbjct: 834 GLLADLHSAGAAVDFSVLYPAGELVDAPLPAWTHQSLLLNRAGQDHQAQGGSSVVVHPLL 893 Query: 905 GSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXXXX 964 GSHV L EEPERH+WQ DVGT AL WLADHQ+H+ ALPGAAYCEM Sbjct: 894 GSHVLLPEEPERHVWQSDVGTEALPWLADHQIHSAPALPGAAYCEMALVAARTILGDAAE 953 Query: 965 XXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDDCPPP 1024 + FEQMLLL ETP+ A+ SV +PG+++FVV+ QDG +R A LHA EDD P Sbjct: 954 VRDVRFEQMLLLDDETPLSAVGSVKSPGIVDFVVETFQDGGAVRRGGAVLHAVEDDDQLP 1013 Query: 1025 AYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVALPAS 1084 AYDI ALL H + +G +LR F E GVQ +V+AEVALP + Sbjct: 1014 AYDIPALLAEHSRTEDGEELRARFDEHGVQYGPAFTGLGNAHIADGAVSSVVAEVALPGA 1073 Query: 1085 IRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNARYCYT 1144 +R QQ +Y IHPALLDACFQ+VGA D +V GL+LPLGVR +R Y TRNA YCY Sbjct: 1074 MRSQQRAYAIHPALLDACFQAVGAHPDV-QVAGNGGLMLPLGVRQIRAYASTRNAHYCYA 1132 Query: 1145 RLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQQRTL 1204 R+T ++ EADLDVLDEHG VL+AVRGL +GTG +E G DR L+ERLLTI WQQR L Sbjct: 1133 RVTSVDTSAVEADLDVLDEHGTVLVAVRGLQLGTGVSEEGNRDRVLNERLLTIEWQQREL 1192 Query: 1205 PESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQD-DPVVSR 1263 PE E G+WLLI T + + DM A+ LTDALK + Q C SW D S Sbjct: 1193 PEVDAAEAGAWLLISTSDGA---DMLAAELTDALKLHSAQ---CATTSWHENAADHAASA 1246 Query: 1264 ERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLFV 1321 ERL QL G VIL P +G DE S + E VRH+VR++REL E+ GE PRLFV Sbjct: 1247 ERLRNQLNAGGFHNAVILLKPDSGDRDENSGVEGVECVRHVVRVVRELPEIMGEAPRLFV 1306 Query: 1322 VTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGSE 1381 VTR AQ V G++ANLEQAGLRGLLRVI +E+P L TT VDVDEH+ E VA+QLLSGSE Sbjct: 1307 VTRGAQTVLGGESANLEQAGLRGLLRVIGAEYPHLHTTHVDVDEHSGSEVVARQLLSGSE 1366 Query: 1382 EDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRVP 1441 EDETAWR G WY ARL+P PL E+R+T V+ + +G+R+ +R PGDLQ++E VA DRV Sbjct: 1367 EDETAWRCGQWYTARLSPMPLRPEERKTTVVEHDTEGMRLQIRTPGDLQTMEFVAFDRVA 1426 Query: 1442 PGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQIGDR 1501 PGPGQ+EVAVS SSINFADVL++FGR+ D + PQLG DF HQ+GDR Sbjct: 1427 PGPGQIEVAVSTSSINFADVLVSFGRYNSPDGQMPQLGTDFAGVVTAVGPDVTDHQVGDR 1486 Query: 1502 VGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGDKVL 1561 VGG S GCW TF+TCD LA +P+GLTD Q WYGL+DL I+ GDKVL Sbjct: 1487 VGGMSPHGCWATFVTCDGALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGDKVL 1546 Query: 1562 IHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRDT 1621 IHS TGGVGQAAI+IARA GAEI+ATAG+P +R +L D+GIEHVYDSRS+EFAE IR DT Sbjct: 1547 IHSGTGGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRSIEFAEAIRADT 1606 Query: 1622 DGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLDL 1681 DGYGVDIVLNSLTGAAQRAGLELL +GGRFVEIGK D+YG+T++GLFPFRR L+FY +DL Sbjct: 1607 DGYGVDIVLNSLTGAAQRAGLELLAWGGRFVEIGKRDIYGDTKMGLFPFRRNLSFYGVDL 1666 Query: 1682 ALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDI 1741 ++S+T P +RELL TV+ TA+GVL P+ THYPL +AA AIR M A+HTGKL+LDI Sbjct: 1667 GMLSITHPRLIRELLTTVYQHTAEGVLPMPQDTHYPLAEAATAIRVMGAADHTGKLLLDI 1726 Query: 1742 PRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQPNPK 1801 PR+G +V +PPEQ PV R DGSYIIT F A K+A AG GRIVL++RS P+ K Sbjct: 1727 PRSGRSAVVLPPEQVPVLRADGSYIITGGLGGLGLFLAEKMATAGAGRIVLSSRSAPSQK 1786 Query: 1802 ARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTNI 1861 A +TIE + + G+D+VVECG+IA+P TA RLV ATAT LPLRGVLH+AAVVEDATL NI Sbjct: 1787 ALETIELIRSIGSDVVVECGDIAQPATAARLVANATATNLPLRGVLHAAAVVEDATLANI 1846 Query: 1862 TDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLFA 1921 TDEL+DRDW+PKVYG+W+LH AT QPLDWFC FSS AA+LGSPGQGAYAAANSW+D F Sbjct: 1847 TDELLDRDWAPKVYGAWHLHQATTDQPLDWFCSFSSAAAMLGSPGQGAYAAANSWLDAFT 1906 Query: 1922 HWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIPI 1981 HWR Q P +AIAWG W E+GRA LAE + I PDEGAYAF+ L+R++R Y+GY PI Sbjct: 1907 HWRHNQNQPATAIAWGPWAEIGRAIALAESSDAAIAPDEGAYAFQTLLRHNRTYTGYAPI 1966 Query: 1982 LGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVIL 2041 +GAPW+ RS +AE F + QG G SKFR EL ALP DEW G+LRR++ EQ S+IL Sbjct: 1967 IGAPWVTAFAERSKFAEAFKALEQGRSGSSKFRSELDALPLDEWPGQLRRMVAEQVSLIL 2026 Query: 2042 RRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAEE 2101 RRTID DR EYGLDSLG LE+RT ++SETGIR++ I T R LA +L LA E Sbjct: 2027 RRTIDPDRQLSEYGLDSLGNLELRTRVQSETGIRISSTDI---TTVRGLADHLFAQLAPE 2083 Query: 2102 EGVAA 2106 E A+ Sbjct: 2084 EAAAS 2088 >sp|O07798|PHAS_MYCTU Tax_Id=1773 (pks2)RecName: Full=Phthioceranic/hydroxyphthioceranic acid synthase; EC=2.3.1.-; AltName: Full=Polyketide synthase pks2;[Mycobacterium tuberculosis] Length = 2126 Score = 2476 bits (6416), Expect = 0.0 Identities = 1263/2127 (59%), Positives = 1538/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPETVTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELPA V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHAV+Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >sp|A5U9F4|PHAS_MYCTA Tax_Id=419947 (pks2)RecName: Full=Phthioceranic/hydroxyphthioceranic acid synthase; EC=2.3.1.-; AltName: Full=Polyketide synthase pks2;[Mycobacterium tuberculosis] Length = 2126 Score = 2476 bits (6416), Expect = 0.0 Identities = 1263/2127 (59%), Positives = 1538/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPETVTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELPA V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHAV+Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >sp|Q7TVK8|PHAS_MYCBO Tax_Id=1765 (pks2)RecName: Full=Phthioceranic/hydroxyphthioceranic acid synthase; EC=2.3.1.-; AltName: Full=Polyketide synthase pks2;[Mycobacterium bovis] Length = 2126 Score = 2476 bits (6416), Expect = 0.0 Identities = 1263/2127 (59%), Positives = 1538/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPETVTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELPA V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHAV+Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >tr|Q73TF4|Q73TF4_MYCPA Tax_Id=1770 (pks2)SubName: Full=Pks2;[Mycobacterium paratuberculosis] Length = 2098 Score = 2476 bits (6416), Expect = 0.0 Identities = 1272/2116 (60%), Positives = 1531/2116 (72%), Gaps = 30/2116 (1%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 M+ S TP+AVIGM CRLPG I+SPD LW +LLRGD+ VTE+P DRWD D+ YDPEPG+PG Sbjct: 11 MDESATPVAVIGMACRLPGAIDSPDALWAALLRGDDFVTEIPLDRWDADEHYDPEPGLPG 70 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSV RWG FLDDV GFDA+FFGISEREAT+IDPQ RLLLETSWEA+E G++PA+L GS Sbjct: 71 RSVCRWGAFLDDVGGFDADFFGISEREATAIDPQHRLLLETSWEALEHAGINPAALTGSR 130 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 T VF GL H+D+ + T AG L PY G + +VASGRI+HTLGLHGPA+T DTACSSG Sbjct: 131 TGVFVGLMHDDHTLRTADAGALDQPYGFMGNSFAVASGRIAHTLGLHGPALTVDTACSSG 190 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 L++VH+ACRSLH GESDLALAGG VLLEP A SAQGMLS+TGRC++F A ADGFV Sbjct: 191 LVSVHVACRSLHHGESDLALAGGATVLLEPRKLAAGSAQGMLSATGRCRAFDAAADGFVS 250 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 SEGCAMVLLKRLPDALRDG+RI A++ GTA NQDG T +L PS Sbjct: 251 SEGCAMVLLKRLPDALRDGDRILAVVRGTAANQDGRTLSLATPSLTAQTAVYRSALAAAG 310 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 + T+ +VEAHGTGTP+GDPIEY SLA +YG PCAL S K+N GH+ ++AGT+GL+K Sbjct: 311 VDAGTVAMVEAHGTGTPVGDPIEYASLAELYGQDGPCALTSVKTNFGHTQSAAGTLGLVK 370 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 A+L+L++G+VP LHF RL D + ++ T LFVPQ+ TPWP P+R AVSS+G+SGT Sbjct: 371 AVLALQHGVVPQNLHFTRLPDKIGQLNTNLFVPQDNTPWP-RKLQQPRRAAVSSYGVSGT 429 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 N H IVE+AP+ S G G LF +SS+S LRETA++LA WV+E Sbjct: 430 NAHAIVEQAPN---------ASGGVKPTPAGPLLFTVSSSSDEGLRETAKRLAGWVKERA 480 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 SV LSDLAYTLAR RAHRPVRTAV+A + EL GL E+AD Y A G D GPVW Sbjct: 481 ASVELSDLAYTLARRRAHRPVRTAVIAGSVDELAAGLHEVADSRTSYLAAFGRDDCGPVW 540 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LLANEPVFA T+ ++EP+IA ES FSVTEA++AP T+TGIDKVQP Sbjct: 541 VFSGQGSQWTQMGAELLANEPVFATTVAEVEPLIARESGFSVTEAMSAPHTLTGIDKVQP 600 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FA+QVALA TM+ +YGVRPGAVIGHS+ D RVICRRS+LM+R+ Sbjct: 601 TIFAMQVALAATMK-SYGVRPGAVIGHSLGETAAAVVAGALSLQDGVRVICRRSRLMSRI 659 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AG+GAM SVELPA+QV SELMARGIDDVV+SV+ASP STVIGG T TVR+L+A WE+RDV Sbjct: 660 AGAGAMASVELPAQQVLSELMARGIDDVVVSVMASPTSTVIGGVTSTVRELVAAWEERDV 719 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +ARE+AVDVASHS QV P+VP+YSA+LFDPRE P+C+ YW+D Sbjct: 720 LAREIAVDVASHSPQVDPILDELADALVELEPTAPEVPFYSASLFDPREQPLCDADYWLD 779 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR+TV+F AAVQAA+EDG+RVF ELSPHPLLT+A+EQTA +LD AALA MRREQ++P Sbjct: 780 NLRHTVRFGAAVQAALEDGHRVFVELSPHPLLTYAIEQTAASLDTPAAALAAMRREQALP 839 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +G+R LLA++HS GAA+DF+ LYP GRLLD PLP WTH L + D ++ + Q TV V Sbjct: 840 HGMRDLLAEVHSVGAAVDFSMLYPDGRLLDVPLPAWTHRHLLLGLDSRDTQPQAGPTVAV 899 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLGSHVRL EEPERH WQ +VGTA L WLADH++H VAALP AAYCE+ Sbjct: 900 HPLLGSHVRLPEEPERHAWQAEVGTATLRWLADHRIHEVAALPAAAYCEIALTAAHTALG 959 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 + F+QMLL+ ETP+ A+A + + FVV+ ++GE++R ATA L AA Sbjct: 960 DASEVRDLRFDQMLLIEDETPVFALAVMASRSAAEFVVETFEEGERVRRATAILAAAGPG 1019 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PPAYD+ ALL A +SV+G +LR FAERGVQ TVLAEVA Sbjct: 1020 ERPPAYDVPALLAARSSSVDGAELRNRFAERGVQYGPAFTGLTAAHTS---GDTVLAEVA 1076 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP ++R QQ +Y+IHPALLDACFQSVGA + G LLLPLGVR +R Y R A Sbjct: 1077 LPGAMRSQQRAYRIHPALLDACFQSVGAASEIQNSGG-GSLLLPLGVRRIRAYASARTAH 1135 Query: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 YCYTR+T G EADLDVL+EHGAVLL+++GL MGTG +E DR L+ERLLT+ W Sbjct: 1136 YCYTRVTSTTATGFEADLDVLNEHGAVLLSIQGLQMGTGASEEASRDRALNERLLTVEWH 1195 Query: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV 1260 ++ L E V+ G+WLL+ T SA+ D+ A+ LTD+LK G +CT++ W + DPV Sbjct: 1196 RQELTEVDPVDAGTWLLVST---SAMADVAATELTDSLKLLGA---DCTSIRWSSRADPV 1249 Query: 1261 VSRERLGRQLR-GR-DGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPR 1318 + + L QLR GR GVV+L GP+ G D++ E VRH+ I+RELA GE PR Sbjct: 1250 ANGKTLRDQLRVGRFTGVVLLTGPKDGDRDDECAARGGEYVRHVAHIVRELAAAPGEPPR 1309 Query: 1319 LFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLS 1378 L+VVTR AQ V GD ANLEQ GLRGLLRVI +E+P RTT +D D HT +A+QL+S Sbjct: 1310 LYVVTRNAQTVLEGDGANLEQGGLRGLLRVIGNEYPQFRTTQIDTDMHTGASLIARQLVS 1369 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GSEEDETAWRN +W ARL SPL ++RRT V++ EHDG+R+H+R PGDLQ++ELVA + Sbjct: 1370 GSEEDETAWRNDEWLTARLRLSPLRPDERRTAVVDHEHDGMRLHIRAPGDLQTMELVACE 1429 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 R+PPGPGQ+EVAV+ SSINFADVL+AFGR P + R PQLG DF H+I Sbjct: 1430 RIPPGPGQIEVAVTASSINFADVLLAFGRHPSFEGRLPQLGTDFAGMVTAVGPDVIEHKI 1489 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG GCW TF+TCDAN+AVTLP GLTD Q WYGL+DLA +K GD Sbjct: 1490 GDHVGGLCPNGCWGTFVTCDANVAVTLPPGLTDAQAAAVTTAHATAWYGLHDLARVKAGD 1549 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHSATGGVGQAAI+IARA GAEIFATAG+ +R MLHD IEHVYDSRSVEFAEQIR Sbjct: 1550 KVLIHSATGGVGQAAIAIARAAGAEIFATAGSSQRRKMLHDKAIEHVYDSRSVEFAEQIR 1609 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 RDTDGYGVD+VLNSLTGAAQ AGL+LL GGRF+EIGK D+YG+T+LGLFPFRR L FY Sbjct: 1610 RDTDGYGVDVVLNSLTGAAQLAGLKLLAPGGRFIEIGKRDIYGDTKLGLFPFRRNLAFYG 1669 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DL LMSV P RVRELL T + ADG+L P THYPLTDAA AIR MS AEHTGKLV Sbjct: 1670 VDLGLMSVDHPLRVRELLDTAYERVADGLLPMPASTHYPLTDAATAIRVMSAAEHTGKLV 1729 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+ R+G S + P+ V+R DGSYIIT F A KLA AGCGRIVL++RS+P Sbjct: 1730 LDVARSGKSSAVLHPDSGRVFRPDGSYIITGGLGGIGLFLAEKLAAAGCGRIVLSSRSEP 1789 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 N + ++ IE + A G+D+VVEC +I +P TA+RLV AAT TGLP+RGVLH+A VVED+ L Sbjct: 1790 NQRVQEMIELVRAIGSDVVVECADITQPGTAERLVAAATTTGLPVRGVLHAAGVVEDSAL 1849 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 IT EL++R W+PKV G+WNLH T G+PLDWFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1850 GGITGELLERCWAPKVVGAWNLHRVTAGEPLDWFCLFSSAAALVGSPGQGAYAAANSWLD 1909 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 F HWRRAQGLP +AIAWGAW E+GRAT AE ITPDEGAYAF+ L+ +DR Y+GY Sbjct: 1910 AFTHWRRAQGLPATAIAWGAWSELGRATGFAEDVGTAITPDEGAYAFQALLCHDRAYTGY 1969 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 P++ WL RS +AE F S G+ G ++F EL LP D+W RLRRL+ EQ S Sbjct: 1970 APVIDTAWLSAFAERSRFAEAFRSTGKSPTGTTRFLAELNTLPHDQWPTRLRRLVSEQVS 2029 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 +ILRRT+D DR EYGLDSLG LE+RT IE+E G+R+ I T R LA +L DTL Sbjct: 2030 LILRRTVDPDRPLSEYGLDSLGNLELRTRIEAEAGVRIKSTAI---TTVRGLAAHLCDTL 2086 Query: 2099 AEEEGVAAPAAMVSPE 2114 AE AAP + V E Sbjct: 2087 AE----AAPTSQVRAE 2098 >tr|C6DP53|C6DP53_MYCTK Tax_Id=478434 SubName: Full=Polyketide synthase pks2;[Mycobacterium tuberculosis] Length = 2126 Score = 2476 bits (6416), Expect = 0.0 Identities = 1263/2127 (59%), Positives = 1538/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPETVTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELPA V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHAV+Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >tr|A4KMU1|A4KMU1_MYCTU Tax_Id=395095 SubName: Full=Polyketide synthase pks2;[Mycobacterium tuberculosis str. Haarlem] Length = 2126 Score = 2476 bits (6416), Expect = 0.0 Identities = 1263/2127 (59%), Positives = 1538/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPETVTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELPA V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHAV+Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >tr|A2VMK1|A2VMK1_MYCTU Tax_Id=348776 SubName: Full=Polyketide synthase pks2;[Mycobacterium tuberculosis C] Length = 2126 Score = 2474 bits (6412), Expect = 0.0 Identities = 1262/2127 (59%), Positives = 1537/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPETVTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELP V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPGLAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHAV+Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >sp|A1KQG0|PHAS_MYCBP Tax_Id=410289 (pks2)RecName: Full=Phthioceranic/hydroxyphthioceranic acid synthase; EC=2.3.1.-; AltName: Full=Polyketide synthase pks2;[Mycobacterium bovis] Length = 2126 Score = 2473 bits (6409), Expect = 0.0 Identities = 1262/2127 (59%), Positives = 1537/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPETVTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELPA V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHA +Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAGDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >tr|C1AIT1|C1AIT1_MYCBT Tax_Id=561275 (pks2)SubName: Full=Polyketide synthase;[Mycobacterium bovis] Length = 2126 Score = 2473 bits (6409), Expect = 0.0 Identities = 1262/2127 (59%), Positives = 1537/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPETVTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELPA V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHA +Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAGDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >tr|A5WU45|A5WU45_MYCTF Tax_Id=336982 SubName: Full=Polyketide synthase pks2;[Mycobacterium tuberculosis] Length = 2126 Score = 2473 bits (6409), Expect = 0.0 Identities = 1262/2127 (59%), Positives = 1537/2127 (72%), Gaps = 35/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 E VTP+AVIGM CRLPGGI+SP+ LW++LLRGD+L+TEVPPDRWD D+FYDP+PGVPGR Sbjct: 21 EPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGR 80 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 +V +WGGFLD+ A FD EFFGI EREA +IDPQQRLLLETSWEA+E GL +LAGS+T Sbjct: 81 TVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT 140 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+TH DY ++ A L PY G + S+ASGR+++ + LHGPA+T DTACSSGL Sbjct: 141 GVFGGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGL 200 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 AVH+ACRSLH+GESD+ALAGG A++LEP + A SA GMLS TGRC++F ADGFV Sbjct: 201 TAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSG 260 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCA+V+LKRLPDAL DG+RI A+I GT+ NQDG T + PS+ Sbjct: 261 EGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGV 320 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 + T+G+VEAHG GTPIGDPIEY S++ VYG PCAL S K+N GH+ ++AG +GLIK Sbjct: 321 DAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKV 380 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++G+VP LHF RL D++ I T LFVP+ TPWP G P+R AVSS+G SGTN Sbjct: 381 VLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTN 440 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH +VE+AP P T P TG LF LS++S ALR+TA++L W+++H D Sbjct: 441 VHAVVEQAPQTEAQPHAASTPP-TGTPA----LFTLSASSADALRQTAQRLTDWIQQHAD 495 Query: 482 SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWV 541 S+VLSDLAYTLAR R HR VRTAV+A+ + EL+ GL E+ADGD +Y VG DRGPVW+ Sbjct: 496 SLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWL 555 Query: 542 FSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPS 601 FSGQGSQWA+MG LL NE VFAAT+ +LEP+IAAES FSVTEA+TAPE VTGID+VQP+ Sbjct: 556 FSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPEAVTGIDRVQPT 615 Query: 602 VFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVA 661 +FA+QVALA TM YGVRPGAVIGHSM D RVICRRSKLM +A Sbjct: 616 IFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIA 674 Query: 662 GSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVM 721 GS AM SVELPA V SEL A GIDDVV++VV +PQSTVI G TE+VR L+ WE+RDV+ Sbjct: 675 GSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVL 734 Query: 722 AREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDN 781 AR VAVDVASHS QV P++PYYSATLFDPRE P C+ YW DN Sbjct: 735 ARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADN 794 Query: 782 LRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPY 841 LR+TV+F+AAV++A++DGYRVFAELSPHPLLTHAV+Q A ++ M VAALAGMRREQ +P Sbjct: 795 LRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPL 854 Query: 842 GLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVH 901 GLR LL DLH+AGAA+DF+ L P GRL+DAPLP W+H LF D +G + R+ G TV VH Sbjct: 855 GLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVH 914 Query: 902 PLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXX 961 PLLG+HVRL EEPERH WQ DVGTA L WL DH++HNVAALPGAAYCEM Sbjct: 915 PLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGE 974 Query: 962 XXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDG--EKMRNATATLHAAED 1019 + FE MLLL +TP+ +A+V +PGV++F V+A Q+G +R A+A L Sbjct: 975 QSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSG 1034 Query: 1020 DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEV 1079 +C PPAYD+A+LLEAHP V+G DLR F + GVQ + T+LAEV Sbjct: 1035 ECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEV 1094 Query: 1080 ALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNA 1139 ALP SIR QQ Y IHPALLDACFQSVGA D+ VGS GLL+PLGVR +R Y P R A Sbjct: 1095 ALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGS--GLLVPLGVRRVRAYAPVRTA 1152 Query: 1140 RYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 RYCYTR+TK+E G EAD+DVLD HG VLLAV GL +GTG +ER + +R L+ERLLTI W Sbjct: 1153 RYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 QR LPE G WLLI AS D+ A+ L DA + + CT + W + DD Sbjct: 1213 HQRELPEMDPSGAGKWLLISDCAAS---DVTATRLADAFREHSAA---CTTMRWPLHDDQ 1266 Query: 1260 VVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELP 1317 + + ++L Q+ + GVV+L G G P + S E VR LV I REL++L G +P Sbjct: 1267 LAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVP 1326 Query: 1318 RLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLL 1377 R++VVTR AQ V + D NLEQ GLRGLLR I +EHP LR T +DVDE T VE++A+QLL Sbjct: 1327 RMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLL 1386 Query: 1378 SGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVAS 1437 + SEEDETAWR+ +WYVARL P+PL ++RRT+V + + G+R+ +R PGD+Q++EL A Sbjct: 1387 ATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAF 1446 Query: 1438 DRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQ 1497 RVPPGPGQ+EVAV SS+NFADVLIAFGR+P + PQLG DF H+ Sbjct: 1447 HRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHK 1506 Query: 1498 IGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVG 1557 +GD VGG S GCW TF+TCDA LA TLP GL D Q WYGL++LA I+ G Sbjct: 1507 VGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAG 1566 Query: 1558 DKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQI 1617 D VLIHS TGGVGQAAI+IARA GAEIFATAG P +R +L ++GIEHVYDSRS+EFAEQI Sbjct: 1567 DTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQI 1626 Query: 1618 RRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFY 1677 RRDT+G GVD+VLNS+TGAAQ AGL+LL F GRFVEIGK D+YG+T+LGLFPFRR L+FY Sbjct: 1627 RRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFY 1686 Query: 1678 YLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKL 1737 +DL L+S T P+ +R+LL TV+ LTA G L P+ THYPL +AA AIR M NAEHTGKL Sbjct: 1687 AVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKL 1746 Query: 1738 VLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQ 1797 VL IP+TG V +PPEQA V+R DGSYIIT F A K+A AGCGRIVL +R+Q Sbjct: 1747 VLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQ 1806 Query: 1798 PNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDAT 1857 P K R+TIE + A G+++VVECG+IA+P TA+RLV A ATGLP+RGVLH+AAVVEDAT Sbjct: 1807 PTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDAT 1866 Query: 1858 LTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWV 1917 L NITDEL+ RDW+PKV+G+W LH AT GQPLDWFCLFSS AAL GSPGQ AY+AANSW+ Sbjct: 1867 LANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWL 1926 Query: 1918 DLFAHWRRAQGLPVSAIAWGAWGEVG----------RATFLAEGGEIMITPDEGAYAFEM 1967 D FAHWR+AQGLP +AIAWGAW ++G RA+ L E ITPDEGAYAFE Sbjct: 1927 DAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEA 1986 Query: 1968 LVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSG 2027 L+R++R Y+GY P++GAPWL RS + E+FSS+ G SKFR+EL LP+DEW Sbjct: 1987 LLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSS--NGSGTSKFRVELNELPRDEWPA 2044 Query: 2028 RLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTA 2087 RLR+L+ EQ S+ILRRT+D DR EYGLDSLG LE+RT IE+ETGIRL PK ++ T Sbjct: 2045 RLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA--TV 2102 Query: 2088 RALAQYLADTLAEEEGVAAPAAMVSPE 2114 R LA +L + LA ++ APAA +S + Sbjct: 2103 RGLADHLYEQLAPDD---APAAALSSQ 2126 >tr|Q7VEZ3|Q7VEZ3_MYCBO Tax_Id=1765 (pks5)SubName: Full=Probable polyketide synthase pks5;[Mycobacterium bovis] Length = 2108 Score = 2454 bits (6360), Expect = 0.0 Identities = 1267/2112 (59%), Positives = 1507/2112 (71%), Gaps = 21/2112 (0%) Query: 3 TSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRS 62 T VTP+AVIGMGCRLPGGI+SPD+LWE+LLRGD+LVTE+P DRWD+D++YDPEPGVPGR+ Sbjct: 12 TRVTPVAVIGMGCRLPGGIDSPDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRT 71 Query: 63 VSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA 122 +WG +LD+V FD EFFGI E+EA +IDPQ RLLLETSWEA+E GGL P +A S T Sbjct: 72 DCKWGAYLDNVGDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTG 130 Query: 123 VFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLM 182 VF GL H DY+++ PY TG N ASGR+++ +GL GPA+T DTACSSGL Sbjct: 131 VFVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTACSSGLT 190 Query: 183 AVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSE 242 A+HLACRSLHDGESD+ALAGG V+LEP + SA GMLS+TGRC +F ADGFV E Sbjct: 191 AIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATGRCHAFDVSADGFVSGE 250 Query: 243 GCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXE 302 GC M+ LKRLPDAL DG+RI A+I GTA NQDG T + PS + Sbjct: 251 GCVMLALKRLPDALADGDRILAVIRGTAANQDGHTVNIATPSRSAQVAAYREALDVAGVD 310 Query: 303 PETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAI 362 P T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ ++AG +GL+KA+ Sbjct: 311 PATVGMVEAHGPGTPVGDPIEYASLAEVYGNDGPCALASVKTNFGHTQSAAGALGLMKAV 370 Query: 363 LSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV 422 L+L++G+VP LHF L D L IET LFVPQE+TPWP TP+R AVSS+GM+GTNV Sbjct: 371 LALQHGVVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV 430 Query: 423 HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS 482 H IVE+AP A P +P T G LF LS++S ALR+TA +LA WV+ Sbjct: 431 HAIVEQAPVPAPESGAPGDTPATPGID-GALLFALSASSQDALRQTAARLADWVDAQGPE 489 Query: 483 VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVF 542 + +DLAYTLAR R HRPVRTAV+AA EL E L E+A G+ Y VG DRGPVWVF Sbjct: 490 LAPADLAYTLARRRGHRPVRTAVLAATTAELTEALREVATGETPYPPAVGQDDRGPVWVF 549 Query: 543 SGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSV 602 SGQGSQWA MG LLA EPVFAATI +EP+IAAES FSVTEA+TAPE VTGID+VQP++ Sbjct: 550 SGQGSQWAGMGADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTL 609 Query: 603 FAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAG 662 FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS LM R+AG Sbjct: 610 FAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRIAG 668 Query: 663 SGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMA 722 +GAM SVELPA+QV SELMARG++D V++VVASPQSTVIGGAT+TVRDL+A WEQRDV+A Sbjct: 669 AGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRDLVAAWEQRDVLA 728 Query: 723 REVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNL 782 REVAVDVASHS QV + P++PYYSAT FDPRE P C+ YWVDNL Sbjct: 729 REVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYYSATSFDPREEPYCDAYYWVDNL 788 Query: 783 RNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG 842 R+TV+FAAAVQAA+EDGYRVF EL+PHPLLTHAV+QTAR+LDMS AALAGMRREQ +P+G Sbjct: 789 RHTVRFAAAVQAALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHG 848 Query: 843 LRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHP 902 LR L DL++AGAA+DFA LYP GRL++APLP W H RL +D +R A TV VHP Sbjct: 849 LRALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHP 906 Query: 903 LLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXX 962 LLGSHVRL EEPERH+WQG+VGT WLADHQ+H AALPGAAYCEM Sbjct: 907 LLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLGEA 966 Query: 963 XXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAE--DD 1020 I FEQMLLL ETPI A+V+APGV+ V+ + DG R A LH DD Sbjct: 967 SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSHDGRYTRQLAAVLHVVREADD 1026 Query: 1021 CP--PPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAE 1078 P PP +IA LL +HP+ V+G ++R+ +RG + TVLAE Sbjct: 1027 APDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAE 1086 Query: 1079 VALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRN 1138 V LP +R Q +Y +HP LLDACFQSV A A + + GLLLPLGVR LR Y R+ Sbjct: 1087 VNLPGPLRSQVKAYGVHPVLLDACFQSVAAH-PAVQGMADGGLLLPLGVRRLRSYGSARH 1145 Query: 1139 ARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIG 1198 ARYC T +T G EADLDVLDEHGAV+LAVRGL +GTG ++ E R L ERLL+I Sbjct: 1146 ARYCCTTVTACGV-GVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGERLLSIE 1204 Query: 1199 WQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDD 1258 W +R LPE+ H EPG+WLLI T +A+ D+ A+ LTDALK + Q CT +SW + D Sbjct: 1205 WHERELPENSHAEPGAWLLISTCDAT---DLVAAQLTDALKVHDAQ---CTTMSWPQRAD 1258 Query: 1259 PVVSRERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 RL QL G GV +L P+ G PD +S + E V+H+VRI RE+ E+ + Sbjct: 1259 HAAQAARLRDQLGTGGFTGVFVLTAPQTGDPDAESPVRGGELVKHVVRIAREIPEITAQE 1318 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRL+V+T AQ V SGD NLEQ G+RGLLRVI +EHP L+ + VDVDE T E VA+QL Sbjct: 1319 PRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGAESVARQL 1378 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 L+ S EDETAWRN WY ARL P+PL E+R+T V++ G+R+ +R PGDLQ+LE A Sbjct: 1379 LAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAGMRLQIRTPGDLQTLEFAA 1438 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EVAV+ SSINFADVL+ FGR+ +D R PQLG DF Sbjct: 1439 LDRVPPGPGEIEVAVTASSINFADVLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSEL 1498 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 ++GDRVGG S GCW TF+TCDA LA LP GLTD Q WYGL DLA IK Sbjct: 1499 KVGDRVGGMSPNGCWATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKA 1558 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 GDKVLIHSATGGVGQAAI+IARA GA+I+ATAGN +R +L D+GIEHVYDSRSVEFAEQ Sbjct: 1559 GDKVLIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ 1618 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IRRDT GYGVDIVLNS+TGAAQ AGL+LL GGRF+EIGK D+Y NTRL L PFRR L F Sbjct: 1619 IRRDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELLPFRRNLAF 1678 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y LDL LMSV+ P VRELL+TV+ LT +GVL P+ THYPL +AA AIR M AEHTGK Sbjct: 1679 YGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPLAEAATAIRVMGAAEHTGK 1738 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 L+LD+P G SV +PPEQA V+R DGSYIIT F A K+A AG GRIVL++RS Sbjct: 1739 LILDVPHAGRSSVVLPPEQARVFRSDGSYIITGGLGGLGLFLAEKMANAGAGRIVLSSRS 1798 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 QP+ KA +TIE + A G+D+VVECG+IA+P TADRLV AATATGLPLRGVLH+AAVVEDA Sbjct: 1799 QPSQKALETIELVRAIGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDA 1858 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELI+RDW+PK YG+W LH AT QPLDWFC FSS AAL+GSPGQGAYAAANSW Sbjct: 1859 TLANITDELIERDWAPKAYGAWQLHRATADQPLDWFCSFSSAAALVGSPGQGAYAAANSW 1918 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQ LP ++IAWGAWG++GRA AE I P+EGAYAFE L+R++R YS Sbjct: 1919 LDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAPEEGAYAFETLLRHNRAYS 1978 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P++G+PWL + SP+AE F S GQ G SKF EL+ LP++EW RLRRLL +Q Sbjct: 1979 GYAPVIGSPWLTAFAQHSPFAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQ 2038 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRRTID DR EYGLDSL E+R +E+ETGIR++ I N T R LA + D Sbjct: 2039 VGLILRRTIDTDRLLSEYGLDSLSSQELRARVEAETGIRISATEI--NTTVRGLADLMCD 2096 Query: 2097 TLAEEEGVAAPA 2108 LA + APA Sbjct: 2097 KLAADRDAPAPA 2108 >tr|C1ANG3|C1ANG3_MYCBT Tax_Id=561275 (pks5)SubName: Full=Putative polyketide synthase;[Mycobacterium bovis] Length = 2108 Score = 2454 bits (6360), Expect = 0.0 Identities = 1267/2112 (59%), Positives = 1507/2112 (71%), Gaps = 21/2112 (0%) Query: 3 TSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRS 62 T VTP+AVIGMGCRLPGGI+SPD+LWE+LLRGD+LVTE+P DRWD+D++YDPEPGVPGR+ Sbjct: 12 TRVTPVAVIGMGCRLPGGIDSPDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRT 71 Query: 63 VSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA 122 +WG +LD+V FD EFFGI E+EA +IDPQ RLLLETSWEA+E GGL P +A S T Sbjct: 72 DCKWGAYLDNVGDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTG 130 Query: 123 VFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLM 182 VF GL H DY+++ PY TG N ASGR+++ +GL GPA+T DTACSSGL Sbjct: 131 VFVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTACSSGLT 190 Query: 183 AVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSE 242 A+HLACRSLHDGESD+ALAGG V+LEP + SA GMLS+TGRC +F ADGFV E Sbjct: 191 AIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATGRCHAFDVSADGFVSGE 250 Query: 243 GCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXE 302 GC M+ LKRLPDAL DG+RI A+I GTA NQDG T + PS + Sbjct: 251 GCVMLALKRLPDALADGDRILAVIRGTAANQDGHTVNIATPSRSAQVAAYREALDVAGVD 310 Query: 303 PETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAI 362 P T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ ++AG +GL+KA+ Sbjct: 311 PATVGMVEAHGPGTPVGDPIEYASLAEVYGNDGPCALASVKTNFGHTQSAAGALGLMKAV 370 Query: 363 LSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV 422 L+L++G+VP LHF L D L IET LFVPQE+TPWP TP+R AVSS+GM+GTNV Sbjct: 371 LALQHGVVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV 430 Query: 423 HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS 482 H IVE+AP A P +P T G LF LS++S ALR+TA +LA WV+ Sbjct: 431 HAIVEQAPVPAPESGAPGDTPATPGID-GALLFALSASSQDALRQTAARLADWVDAQGPE 489 Query: 483 VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVF 542 + +DLAYTLAR R HRPVRTAV+AA EL E L E+A G+ Y VG DRGPVWVF Sbjct: 490 LAPADLAYTLARRRGHRPVRTAVLAATTAELTEALREVATGETPYPPAVGQDDRGPVWVF 549 Query: 543 SGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSV 602 SGQGSQWA MG LLA EPVFAATI +EP+IAAES FSVTEA+TAPE VTGID+VQP++ Sbjct: 550 SGQGSQWAGMGADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTL 609 Query: 603 FAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAG 662 FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS LM R+AG Sbjct: 610 FAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRIAG 668 Query: 663 SGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMA 722 +GAM SVELPA+QV SELMARG++D V++VVASPQSTVIGGAT+TVRDL+A WEQRDV+A Sbjct: 669 AGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRDLVAAWEQRDVLA 728 Query: 723 REVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNL 782 REVAVDVASHS QV + P++PYYSAT FDPRE P C+ YWVDNL Sbjct: 729 REVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYYSATSFDPREEPYCDAYYWVDNL 788 Query: 783 RNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG 842 R+TV+FAAAVQAA+EDGYRVF EL+PHPLLTHAV+QTAR+LDMS AALAGMRREQ +P+G Sbjct: 789 RHTVRFAAAVQAALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHG 848 Query: 843 LRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHP 902 LR L DL++AGAA+DFA LYP GRL++APLP W H RL +D +R A TV VHP Sbjct: 849 LRALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHP 906 Query: 903 LLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXX 962 LLGSHVRL EEPERH+WQG+VGT WLADHQ+H AALPGAAYCEM Sbjct: 907 LLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLGEA 966 Query: 963 XXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAE--DD 1020 I FEQMLLL ETPI A+V+APGV+ V+ + DG R A LH DD Sbjct: 967 SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSHDGRYTRQLAAVLHVVREADD 1026 Query: 1021 CP--PPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAE 1078 P PP +IA LL +HP+ V+G ++R+ +RG + TVLAE Sbjct: 1027 APDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAE 1086 Query: 1079 VALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRN 1138 V LP +R Q +Y +HP LLDACFQSV A A + + GLLLPLGVR LR Y R+ Sbjct: 1087 VNLPGPLRSQVKAYGVHPVLLDACFQSVAAH-PAVQGMADGGLLLPLGVRRLRSYGSARH 1145 Query: 1139 ARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIG 1198 ARYC T +T G EADLDVLDEHGAV+LAVRGL +GTG ++ E R L ERLL+I Sbjct: 1146 ARYCCTTVTACGV-GVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGERLLSIE 1204 Query: 1199 WQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDD 1258 W +R LPE+ H EPG+WLLI T +A+ D+ A+ LTDALK + Q CT +SW + D Sbjct: 1205 WHERELPENSHAEPGAWLLISTCDAT---DLVAAQLTDALKVHDAQ---CTTMSWPQRAD 1258 Query: 1259 PVVSRERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 RL QL G GV +L P+ G PD +S + E V+H+VRI RE+ E+ + Sbjct: 1259 HAAQAARLRDQLGTGGFTGVFVLTAPQTGDPDAESPVRGGELVKHVVRIAREIPEITAQE 1318 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRL+V+T AQ V SGD NLEQ G+RGLLRVI +EHP L+ + VDVDE T E VA+QL Sbjct: 1319 PRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGAESVARQL 1378 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 L+ S EDETAWRN WY ARL P+PL E+R+T V++ G+R+ +R PGDLQ+LE A Sbjct: 1379 LAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAGMRLQIRTPGDLQTLEFAA 1438 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EVAV+ SSINFADVL+ FGR+ +D R PQLG DF Sbjct: 1439 LDRVPPGPGEIEVAVTASSINFADVLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSEL 1498 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 ++GDRVGG S GCW TF+TCDA LA LP GLTD Q WYGL DLA IK Sbjct: 1499 KVGDRVGGMSPNGCWATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKA 1558 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 GDKVLIHSATGGVGQAAI+IARA GA+I+ATAGN +R +L D+GIEHVYDSRSVEFAEQ Sbjct: 1559 GDKVLIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ 1618 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IRRDT GYGVDIVLNS+TGAAQ AGL+LL GGRF+EIGK D+Y NTRL L PFRR L F Sbjct: 1619 IRRDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELLPFRRNLAF 1678 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y LDL LMSV+ P VRELL+TV+ LT +GVL P+ THYPL +AA AIR M AEHTGK Sbjct: 1679 YGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPLAEAATAIRVMGAAEHTGK 1738 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 L+LD+P G SV +PPEQA V+R DGSYIIT F A K+A AG GRIVL++RS Sbjct: 1739 LILDVPHAGRSSVVLPPEQARVFRSDGSYIITGGLGGLGLFLAEKMANAGAGRIVLSSRS 1798 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 QP+ KA +TIE + A G+D+VVECG+IA+P TADRLV AATATGLPLRGVLH+AAVVEDA Sbjct: 1799 QPSQKALETIELVRAIGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDA 1858 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELI+RDW+PK YG+W LH AT QPLDWFC FSS AAL+GSPGQGAYAAANSW Sbjct: 1859 TLANITDELIERDWAPKAYGAWQLHRATADQPLDWFCSFSSAAALVGSPGQGAYAAANSW 1918 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQ LP ++IAWGAWG++GRA AE I P+EGAYAFE L+R++R YS Sbjct: 1919 LDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAPEEGAYAFETLLRHNRAYS 1978 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P++G+PWL + SP+AE F S GQ G SKF EL+ LP++EW RLRRLL +Q Sbjct: 1979 GYAPVIGSPWLTAFAQHSPFAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQ 2038 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRRTID DR EYGLDSL E+R +E+ETGIR++ I N T R LA + D Sbjct: 2039 VGLILRRTIDTDRLLSEYGLDSLSSQELRARVEAETGIRISATEI--NTTVRGLADLMCD 2096 Query: 2097 TLAEEEGVAAPA 2108 LA + APA Sbjct: 2097 KLAADRDAPAPA 2108 >tr|A1KIV7|A1KIV7_MYCBP Tax_Id=410289 (pks5)SubName: Full=Probable polyketide synthase pks5;[Mycobacterium bovis] Length = 2108 Score = 2454 bits (6360), Expect = 0.0 Identities = 1267/2112 (59%), Positives = 1507/2112 (71%), Gaps = 21/2112 (0%) Query: 3 TSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRS 62 T VTP+AVIGMGCRLPGGI+SPD+LWE+LLRGD+LVTE+P DRWD+D++YDPEPGVPGR+ Sbjct: 12 TRVTPVAVIGMGCRLPGGIDSPDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRT 71 Query: 63 VSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA 122 +WG +LD+V FD EFFGI E+EA +IDPQ RLLLETSWEA+E GGL P +A S T Sbjct: 72 DCKWGAYLDNVGDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTG 130 Query: 123 VFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLM 182 VF GL H DY+++ PY TG N ASGR+++ +GL GPA+T DTACSSGL Sbjct: 131 VFVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTACSSGLT 190 Query: 183 AVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSE 242 A+HLACRSLHDGESD+ALAGG V+LEP + SA GMLS+TGRC +F ADGFV E Sbjct: 191 AIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATGRCHAFDVSADGFVSGE 250 Query: 243 GCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXE 302 GC M+ LKRLPDAL DG+RI A+I GTA NQDG T + PS + Sbjct: 251 GCVMLALKRLPDALADGDRILAVIRGTAANQDGHTVNIATPSRSAQVAAYREALDVAGVD 310 Query: 303 PETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAI 362 P T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ ++AG +GL+KA+ Sbjct: 311 PATVGMVEAHGPGTPVGDPIEYASLAEVYGNDGPCALASVKTNFGHTQSAAGALGLMKAV 370 Query: 363 LSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV 422 L+L++G+VP LHF L D L IET LFVPQE+TPWP TP+R AVSS+GM+GTNV Sbjct: 371 LALQHGVVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV 430 Query: 423 HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS 482 H IVE+AP A P +P T G LF LS++S ALR+TA +LA WV+ Sbjct: 431 HAIVEQAPVPAPESGAPGDTPATPGID-GALLFALSASSQDALRQTAARLADWVDAQGPE 489 Query: 483 VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVF 542 + +DLAYTLAR R HRPVRTAV+AA EL E L E+A G+ Y VG DRGPVWVF Sbjct: 490 LAPADLAYTLARRRGHRPVRTAVLAATTAELTEALREVATGETPYPPAVGQDDRGPVWVF 549 Query: 543 SGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSV 602 SGQGSQWA MG LLA EPVFAATI +EP+IAAES FSVTEA+TAPE VTGID+VQP++ Sbjct: 550 SGQGSQWAGMGADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTL 609 Query: 603 FAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAG 662 FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS LM R+AG Sbjct: 610 FAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRIAG 668 Query: 663 SGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMA 722 +GAM SVELPA+QV SELMARG++D V++VVASPQSTVIGGAT+TVRDL+A WEQRDV+A Sbjct: 669 AGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRDLVAAWEQRDVLA 728 Query: 723 REVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNL 782 REVAVDVASHS QV + P++PYYSAT FDPRE P C+ YWVDNL Sbjct: 729 REVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYYSATSFDPREEPYCDAYYWVDNL 788 Query: 783 RNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG 842 R+TV+FAAAVQAA+EDGYRVF EL+PHPLLTHAV+QTAR+LDMS AALAGMRREQ +P+G Sbjct: 789 RHTVRFAAAVQAALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHG 848 Query: 843 LRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHP 902 LR L DL++AGAA+DFA LYP GRL++APLP W H RL +D +R A TV VHP Sbjct: 849 LRALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHP 906 Query: 903 LLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXX 962 LLGSHVRL EEPERH+WQG+VGT WLADHQ+H AALPGAAYCEM Sbjct: 907 LLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLGEA 966 Query: 963 XXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAE--DD 1020 I FEQMLLL ETPI A+V+APGV+ V+ + DG R A LH DD Sbjct: 967 SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSHDGRYTRQLAAVLHVVREADD 1026 Query: 1021 CP--PPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAE 1078 P PP +IA LL +HP+ V+G ++R+ +RG + TVLAE Sbjct: 1027 APDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAE 1086 Query: 1079 VALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRN 1138 V LP +R Q +Y +HP LLDACFQSV A A + + GLLLPLGVR LR Y R+ Sbjct: 1087 VNLPGPLRSQVKAYGVHPVLLDACFQSVAAH-PAVQGMADGGLLLPLGVRRLRSYGSARH 1145 Query: 1139 ARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIG 1198 ARYC T +T G EADLDVLDEHGAV+LAVRGL +GTG ++ E R L ERLL+I Sbjct: 1146 ARYCCTTVTACGV-GVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGERLLSIE 1204 Query: 1199 WQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDD 1258 W +R LPE+ H EPG+WLLI T +A+ D+ A+ LTDALK + Q CT +SW + D Sbjct: 1205 WHERELPENSHAEPGAWLLISTCDAT---DLVAAQLTDALKVHDAQ---CTTMSWPQRAD 1258 Query: 1259 PVVSRERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 RL QL G GV +L P+ G PD +S + E V+H+VRI RE+ E+ + Sbjct: 1259 HAAQAARLRDQLGTGGFTGVFVLTAPQTGDPDAESPVRGGELVKHVVRIAREIPEITAQE 1318 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRL+V+T AQ V SGD NLEQ G+RGLLRVI +EHP L+ + VDVDE T E VA+QL Sbjct: 1319 PRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGAESVARQL 1378 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 L+ S EDETAWRN WY ARL P+PL E+R+T V++ G+R+ +R PGDLQ+LE A Sbjct: 1379 LAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAGMRLQIRTPGDLQTLEFAA 1438 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EVAV+ SSINFADVL+ FGR+ +D R PQLG DF Sbjct: 1439 LDRVPPGPGEIEVAVTASSINFADVLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSEL 1498 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 ++GDRVGG S GCW TF+TCDA LA LP GLTD Q WYGL DLA IK Sbjct: 1499 KVGDRVGGMSPNGCWATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKA 1558 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 GDKVLIHSATGGVGQAAI+IARA GA+I+ATAGN +R +L D+GIEHVYDSRSVEFAEQ Sbjct: 1559 GDKVLIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ 1618 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IRRDT GYGVDIVLNS+TGAAQ AGL+LL GGRF+EIGK D+Y NTRL L PFRR L F Sbjct: 1619 IRRDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELLPFRRNLAF 1678 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y LDL LMSV+ P VRELL+TV+ LT +GVL P+ THYPL +AA AIR M AEHTGK Sbjct: 1679 YGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPLAEAATAIRVMGAAEHTGK 1738 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 L+LD+P G SV +PPEQA V+R DGSYIIT F A K+A AG GRIVL++RS Sbjct: 1739 LILDVPHAGRSSVVLPPEQARVFRSDGSYIITGGLGGLGLFLAEKMANAGAGRIVLSSRS 1798 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 QP+ KA +TIE + A G+D+VVECG+IA+P TADRLV AATATGLPLRGVLH+AAVVEDA Sbjct: 1799 QPSQKALETIELVRAIGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDA 1858 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELI+RDW+PK YG+W LH AT QPLDWFC FSS AAL+GSPGQGAYAAANSW Sbjct: 1859 TLANITDELIERDWAPKAYGAWQLHRATADQPLDWFCSFSSAAALVGSPGQGAYAAANSW 1918 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQ LP ++IAWGAWG++GRA AE I P+EGAYAFE L+R++R YS Sbjct: 1919 LDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAPEEGAYAFETLLRHNRAYS 1978 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P++G+PWL + SP+AE F S GQ G SKF EL+ LP++EW RLRRLL +Q Sbjct: 1979 GYAPVIGSPWLTAFAQHSPFAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQ 2038 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRRTID DR EYGLDSL E+R +E+ETGIR++ I N T R LA + D Sbjct: 2039 VGLILRRTIDTDRLLSEYGLDSLSSQELRARVEAETGIRISATEI--NTTVRGLADLMCD 2096 Query: 2097 TLAEEEGVAAPA 2108 LA + APA Sbjct: 2097 KLAADRDAPAPA 2108 >tr|O53901|O53901_MYCTU Tax_Id=1773 (pks5)SubName: Full=Probable polyketide synthase pks5;[Mycobacterium tuberculosis] Length = 2108 Score = 2454 bits (6359), Expect = 0.0 Identities = 1267/2112 (59%), Positives = 1507/2112 (71%), Gaps = 21/2112 (0%) Query: 3 TSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRS 62 T VTP+AVIGMGCRLPGGI+SPD+LWE+LLRGD+LVTE+P DRWD+D++YDPEPGVPGR+ Sbjct: 12 TRVTPVAVIGMGCRLPGGIDSPDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRT 71 Query: 63 VSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA 122 +WG +LD+V FD EFFGI E+EA +IDPQ RLLLETSWEA+E GGL P +A S T Sbjct: 72 DCKWGAYLDNVGDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTG 130 Query: 123 VFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLM 182 VF GL H DY+++ PY TG N ASGR+++ +GL GPA+T DTACSSGL Sbjct: 131 VFVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTACSSGLT 190 Query: 183 AVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSE 242 A+HLACRSLHDGESD+ALAGG V+LEP + SA GMLS+TGRC +F ADGFV E Sbjct: 191 AIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATGRCHAFDVSADGFVSGE 250 Query: 243 GCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXE 302 GC M+ LKRLPDAL DG+RI A+I GTA NQDG T + PS + Sbjct: 251 GCVMLALKRLPDALADGDRILAVIRGTAANQDGHTVNIATPSRSAQVAAYREALDVAGVD 310 Query: 303 PETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAI 362 P T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ ++AG +GL+KA+ Sbjct: 311 PATVGMVEAHGPGTPVGDPIEYASLAEVYGNDGPCALASVKTNFGHTQSAAGALGLMKAV 370 Query: 363 LSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV 422 L+L++G+VP LHF L D L IET LFVPQE+TPWP TP+R AVSS+GM+GTNV Sbjct: 371 LALQHGVVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV 430 Query: 423 HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS 482 H IVE+AP A P +P T G LF LS++S ALR+TA +LA WV+ Sbjct: 431 HAIVEQAPVPAPESGAPGDTPATPGID-GALLFALSASSQDALRQTAARLADWVDAQGPE 489 Query: 483 VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVF 542 + +DLAYTLAR R HRPVRTAV+AA EL E L E+A G+ Y VG DRGPVWVF Sbjct: 490 LAPADLAYTLARRRGHRPVRTAVLAATTAELTEALREVATGEPPYPPAVGQDDRGPVWVF 549 Query: 543 SGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSV 602 SGQGSQWA MG LLA EPVFAATI +EP+IAAES FSVTEA+TAPE VTGID+VQP++ Sbjct: 550 SGQGSQWAGMGADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTL 609 Query: 603 FAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAG 662 FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS LM R+AG Sbjct: 610 FAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRIAG 668 Query: 663 SGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMA 722 +GAM SVELPA+QV SELMARG++D V++VVASPQSTVIGGAT+TVRDL+A WEQRDV+A Sbjct: 669 AGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRDLVAAWEQRDVLA 728 Query: 723 REVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNL 782 REVAVDVASHS QV + P++PYYSAT FDPRE P C+ YWVDNL Sbjct: 729 REVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYYSATSFDPREEPYCDAYYWVDNL 788 Query: 783 RNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG 842 R+TV+FAAAVQAA+EDGYRVF EL+PHPLLTHAV+QTAR+LDMS AALAGMRREQ +P+G Sbjct: 789 RHTVRFAAAVQAALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHG 848 Query: 843 LRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHP 902 LR L DL++AGAA+DFA LYP GRL++APLP W H RL +D +R A TV VHP Sbjct: 849 LRALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHP 906 Query: 903 LLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXX 962 LLGSHVRL EEPERH+WQG+VGT WLADHQ+H AALPGAAYCEM Sbjct: 907 LLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLGEA 966 Query: 963 XXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAE--DD 1020 I FEQMLLL ETPI A+V+APGV+ V+ + DG R A LH DD Sbjct: 967 SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSHDGRYTRQLAAVLHVVREADD 1026 Query: 1021 CP--PPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAE 1078 P PP +IA LL +HP+ V+G ++R+ +RG + TVLAE Sbjct: 1027 APDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAE 1086 Query: 1079 VALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRN 1138 V LP +R Q +Y +HP LLDACFQSV A A + + GLLLPLGVR LR Y R+ Sbjct: 1087 VNLPGPLRSQVKAYGVHPVLLDACFQSVAAH-PAVQGMADGGLLLPLGVRRLRSYGSARH 1145 Query: 1139 ARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIG 1198 ARYC T +T G EADLDVLDEHGAV+LAVRGL +GTG ++ E R L ERLL+I Sbjct: 1146 ARYCCTTVTACGV-GVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGERLLSIE 1204 Query: 1199 WQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDD 1258 W +R LPE+ H EPG+WLLI T +A+ D+ A+ LTDALK + Q CT +SW + D Sbjct: 1205 WHERELPENSHAEPGAWLLISTCDAT---DLVAAQLTDALKVHDAQ---CTTMSWPQRAD 1258 Query: 1259 PVVSRERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 RL QL G GV +L P+ G PD +S + E V+H+VRI RE+ E+ + Sbjct: 1259 HAAQAARLRDQLGTGGFTGVFVLTAPQTGDPDAESPVRGGELVKHVVRIAREIPEITAQE 1318 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRL+V+T AQ V SGD NLEQ G+RGLLRVI +EHP L+ + VDVDE T E VA+QL Sbjct: 1319 PRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGAESVARQL 1378 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 L+ S EDETAWRN WY ARL P+PL E+R+T V++ G+R+ +R PGDLQ+LE A Sbjct: 1379 LAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAGMRLQIRTPGDLQTLEFAA 1438 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EVAV+ SSINFADVL+ FGR+ +D R PQLG DF Sbjct: 1439 FDRVPPGPGEIEVAVTASSINFADVLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSEL 1498 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 ++GDRVGG S GCW TF+TCDA LA LP GLTD Q WYGL DLA IK Sbjct: 1499 KVGDRVGGMSPNGCWATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKA 1558 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 GDKVLIHSATGGVGQAAI+IARA GA+I+ATAGN +R +L D+GIEHVYDSRSVEFAEQ Sbjct: 1559 GDKVLIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ 1618 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IRRDT GYGVDIVLNS+TGAAQ AGL+LL GGRF+EIGK D+Y NTRL L PFRR L F Sbjct: 1619 IRRDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELLPFRRNLAF 1678 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y LDL LMSV+ P VRELL+TV+ LT +GVL P+ THYPL +AA AIR M AEHTGK Sbjct: 1679 YGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPLAEAATAIRVMGAAEHTGK 1738 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 L+LD+P G SV +PPEQA V+R DGSYIIT F A K+A AG GRIVL++RS Sbjct: 1739 LILDVPHAGRSSVVLPPEQARVFRSDGSYIITGGLGGLGLFLAEKMANAGAGRIVLSSRS 1798 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 QP+ KA +TIE + A G+D+VVECG+IA+P TADRLV AATATGLPLRGVLH+AAVVEDA Sbjct: 1799 QPSQKALETIELVRAIGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDA 1858 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELI+RDW+PK YG+W LH AT QPLDWFC FSS AAL+GSPGQGAYAAANSW Sbjct: 1859 TLANITDELIERDWAPKAYGAWQLHRATADQPLDWFCSFSSAAALVGSPGQGAYAAANSW 1918 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQ LP ++IAWGAWG++GRA AE I P+EGAYAFE L+R++R YS Sbjct: 1919 LDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAPEEGAYAFETLLRHNRAYS 1978 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P++G+PWL + SP+AE F S GQ G SKF EL+ LP++EW RLRRLL +Q Sbjct: 1979 GYAPVIGSPWLTAFAQHSPFAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQ 2038 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRRTID DR EYGLDSL E+R +E+ETGIR++ I N T R LA + D Sbjct: 2039 VGLILRRTIDTDRLLSEYGLDSLSSQELRARVEAETGIRISATEI--NTTVRGLADLMCD 2096 Query: 2097 TLAEEEGVAAPA 2108 LA + APA Sbjct: 2097 KLAADRDAPAPA 2108 >tr|C6DSR5|C6DSR5_MYCTK Tax_Id=478434 SubName: Full=Polyketide synthase pks5;[Mycobacterium tuberculosis] Length = 2108 Score = 2454 bits (6359), Expect = 0.0 Identities = 1267/2112 (59%), Positives = 1507/2112 (71%), Gaps = 21/2112 (0%) Query: 3 TSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRS 62 T VTP+AVIGMGCRLPGGI+SPD+LWE+LLRGD+LVTE+P DRWD+D++YDPEPGVPGR+ Sbjct: 12 TRVTPVAVIGMGCRLPGGIDSPDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRT 71 Query: 63 VSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA 122 +WG +LD+V FD EFFGI E+EA +IDPQ RLLLETSWEA+E GGL P +A S T Sbjct: 72 DCKWGAYLDNVGDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTG 130 Query: 123 VFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLM 182 VF GL H DY+++ PY TG N ASGR+++ +GL GPA+T DTACSSGL Sbjct: 131 VFVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTACSSGLT 190 Query: 183 AVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSE 242 A+HLACRSLHDGESD+ALAGG V+LEP + SA GMLS+TGRC +F ADGFV E Sbjct: 191 AIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATGRCHAFDVSADGFVSGE 250 Query: 243 GCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXE 302 GC M+ LKRLPDAL DG+RI A+I GTA NQDG T + PS + Sbjct: 251 GCVMLALKRLPDALADGDRILAVIRGTAANQDGHTVNIATPSRSAQVAAYREALDVAGVD 310 Query: 303 PETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAI 362 P T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ ++AG +GL+KA+ Sbjct: 311 PATVGMVEAHGPGTPVGDPIEYASLAEVYGNDGPCALASVKTNFGHTQSAAGALGLMKAV 370 Query: 363 LSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV 422 L+L++G+VP LHF L D L IET LFVPQE+TPWP TP+R AVSS+GM+GTNV Sbjct: 371 LALQHGVVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV 430 Query: 423 HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS 482 H IVE+AP A P +P T G LF LS++S ALR+TA +LA WV+ Sbjct: 431 HAIVEQAPVPAPESGAPGDTPATPGID-GALLFALSASSQDALRQTAARLADWVDAQGPE 489 Query: 483 VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVF 542 + +DLAYTLAR R HRPVRTAV+AA EL E L E+A G+ Y VG DRGPVWVF Sbjct: 490 LAPADLAYTLARRRGHRPVRTAVLAATTAELTEALREVATGEPPYPPAVGQDDRGPVWVF 549 Query: 543 SGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSV 602 SGQGSQWA MG LLA EPVFAATI +EP+IAAES FSVTEA+TAPE VTGID+VQP++ Sbjct: 550 SGQGSQWAGMGADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTL 609 Query: 603 FAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAG 662 FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS LM R+AG Sbjct: 610 FAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRIAG 668 Query: 663 SGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMA 722 +GAM SVELPA+QV SELMARG++D V++VVASPQSTVIGGAT+TVRDL+A WEQRDV+A Sbjct: 669 AGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRDLVAAWEQRDVLA 728 Query: 723 REVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNL 782 REVAVDVASHS QV + P++PYYSAT FDPRE P C+ YWVDNL Sbjct: 729 REVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYYSATSFDPREEPYCDAYYWVDNL 788 Query: 783 RNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG 842 R+TV+FAAAVQAA+EDGYRVF EL+PHPLLTHAV+QTAR+LDMS AALAGMRREQ +P+G Sbjct: 789 RHTVRFAAAVQAALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHG 848 Query: 843 LRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHP 902 LR L DL++AGAA+DFA LYP GRL++APLP W H RL +D +R A TV VHP Sbjct: 849 LRALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHP 906 Query: 903 LLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXX 962 LLGSHVRL EEPERH+WQG+VGT WLADHQ+H AALPGAAYCEM Sbjct: 907 LLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLGEA 966 Query: 963 XXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAE--DD 1020 I FEQMLLL ETPI A+V+APGV+ V+ + DG R A LH DD Sbjct: 967 SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSHDGRYTRQLAAVLHVVREADD 1026 Query: 1021 CP--PPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAE 1078 P PP +IA LL +HP+ V+G ++R+ +RG + TVLAE Sbjct: 1027 APDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAE 1086 Query: 1079 VALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRN 1138 V LP +R Q +Y +HP LLDACFQSV A A + + GLLLPLGVR LR Y R+ Sbjct: 1087 VNLPGPLRSQVKAYGVHPVLLDACFQSVAAH-PAVQGMADGGLLLPLGVRRLRSYGSARH 1145 Query: 1139 ARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIG 1198 ARYC T +T G EADLDVLDEHGAV+LAVRGL +GTG ++ E R L ERLL+I Sbjct: 1146 ARYCCTTVTACGV-GVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGERLLSIE 1204 Query: 1199 WQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDD 1258 W +R LPE+ H EPG+WLLI T +A+ D+ A+ LTDALK + Q CT +SW + D Sbjct: 1205 WHERELPENSHAEPGAWLLISTCDAT---DLVAAQLTDALKVHDAQ---CTTMSWPQRAD 1258 Query: 1259 PVVSRERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 RL QL G GV +L P+ G PD +S + E V+H+VRI RE+ E+ + Sbjct: 1259 HAAQAARLRDQLGTGGFTGVFVLTAPQTGDPDAESPVRGGELVKHVVRIAREIPEITAQE 1318 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRL+V+T AQ V SGD NLEQ G+RGLLRVI +EHP L+ + VDVDE T E VA+QL Sbjct: 1319 PRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGAESVARQL 1378 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 L+ S EDETAWRN WY ARL P+PL E+R+T V++ G+R+ +R PGDLQ+LE A Sbjct: 1379 LAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAGMRLQIRTPGDLQTLEFAA 1438 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EVAV+ SSINFADVL+ FGR+ +D R PQLG DF Sbjct: 1439 FDRVPPGPGEIEVAVTASSINFADVLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSEL 1498 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 ++GDRVGG S GCW TF+TCDA LA LP GLTD Q WYGL DLA IK Sbjct: 1499 KVGDRVGGMSPNGCWATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKA 1558 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 GDKVLIHSATGGVGQAAI+IARA GA+I+ATAGN +R +L D+GIEHVYDSRSVEFAEQ Sbjct: 1559 GDKVLIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ 1618 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IRRDT GYGVDIVLNS+TGAAQ AGL+LL GGRF+EIGK D+Y NTRL L PFRR L F Sbjct: 1619 IRRDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELLPFRRNLAF 1678 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y LDL LMSV+ P VRELL+TV+ LT +GVL P+ THYPL +AA AIR M AEHTGK Sbjct: 1679 YGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPLAEAATAIRVMGAAEHTGK 1738 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 L+LD+P G SV +PPEQA V+R DGSYIIT F A K+A AG GRIVL++RS Sbjct: 1739 LILDVPHAGRSSVVLPPEQARVFRSDGSYIITGGLGGLGLFLAEKMANAGAGRIVLSSRS 1798 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 QP+ KA +TIE + A G+D+VVECG+IA+P TADRLV AATATGLPLRGVLH+AAVVEDA Sbjct: 1799 QPSQKALETIELVRAIGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDA 1858 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELI+RDW+PK YG+W LH AT QPLDWFC FSS AAL+GSPGQGAYAAANSW Sbjct: 1859 TLANITDELIERDWAPKAYGAWQLHRATADQPLDWFCSFSSAAALVGSPGQGAYAAANSW 1918 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQ LP ++IAWGAWG++GRA AE I P+EGAYAFE L+R++R YS Sbjct: 1919 LDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAPEEGAYAFETLLRHNRAYS 1978 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P++G+PWL + SP+AE F S GQ G SKF EL+ LP++EW RLRRLL +Q Sbjct: 1979 GYAPVIGSPWLTAFAQHSPFAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQ 2038 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRRTID DR EYGLDSL E+R +E+ETGIR++ I N T R LA + D Sbjct: 2039 VGLILRRTIDTDRLLSEYGLDSLSSQELRARVEAETGIRISATEI--NTTVRGLADLMCD 2096 Query: 2097 TLAEEEGVAAPA 2108 LA + APA Sbjct: 2097 KLAADRDAPAPA 2108 >tr|A5U2N4|A5U2N4_MYCTA Tax_Id=419947 (pks5)SubName: Full=Putative polyketide synthase pks5;[Mycobacterium tuberculosis] Length = 2108 Score = 2454 bits (6359), Expect = 0.0 Identities = 1267/2112 (59%), Positives = 1507/2112 (71%), Gaps = 21/2112 (0%) Query: 3 TSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRS 62 T VTP+AVIGMGCRLPGGI+SPD+LWE+LLRGD+LVTE+P DRWD+D++YDPEPGVPGR+ Sbjct: 12 TRVTPVAVIGMGCRLPGGIDSPDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRT 71 Query: 63 VSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA 122 +WG +LD+V FD EFFGI E+EA +IDPQ RLLLETSWEA+E GGL P +A S T Sbjct: 72 DCKWGAYLDNVGDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTG 130 Query: 123 VFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLM 182 VF GL H DY+++ PY TG N ASGR+++ +GL GPA+T DTACSSGL Sbjct: 131 VFVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTACSSGLT 190 Query: 183 AVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSE 242 A+HLACRSLHDGESD+ALAGG V+LEP + SA GMLS+TGRC +F ADGFV E Sbjct: 191 AIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATGRCHAFDVSADGFVSGE 250 Query: 243 GCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXE 302 GC M+ LKRLPDAL DG+RI A+I GTA NQDG T + PS + Sbjct: 251 GCVMLALKRLPDALADGDRILAVIRGTAANQDGHTVNIATPSRSAQVAAYREALDVAGVD 310 Query: 303 PETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAI 362 P T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ ++AG +GL+KA+ Sbjct: 311 PATVGMVEAHGPGTPVGDPIEYASLAEVYGNDGPCALASVKTNFGHTQSAAGALGLMKAV 370 Query: 363 LSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV 422 L+L++G+VP LHF L D L IET LFVPQE+TPWP TP+R AVSS+GM+GTNV Sbjct: 371 LALQHGVVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV 430 Query: 423 HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS 482 H IVE+AP A P +P T G LF LS++S ALR+TA +LA WV+ Sbjct: 431 HAIVEQAPVPAPESGAPGDTPATPGID-GALLFALSASSQDALRQTAARLADWVDAQGPE 489 Query: 483 VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVF 542 + +DLAYTLAR R HRPVRTAV+AA EL E L E+A G+ Y VG DRGPVWVF Sbjct: 490 LAPADLAYTLARRRGHRPVRTAVLAATTAELTEALREVATGEPPYPPAVGQDDRGPVWVF 549 Query: 543 SGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSV 602 SGQGSQWA MG LLA EPVFAATI +EP+IAAES FSVTEA+TAPE VTGID+VQP++ Sbjct: 550 SGQGSQWAGMGADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTL 609 Query: 603 FAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAG 662 FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS LM R+AG Sbjct: 610 FAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRIAG 668 Query: 663 SGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMA 722 +GAM SVELPA+QV SELMARG++D V++VVASPQSTVIGGAT+TVRDL+A WEQRDV+A Sbjct: 669 AGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRDLVAAWEQRDVLA 728 Query: 723 REVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNL 782 REVAVDVASHS QV + P++PYYSAT FDPRE P C+ YWVDNL Sbjct: 729 REVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYYSATSFDPREEPYCDAYYWVDNL 788 Query: 783 RNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG 842 R+TV+FAAAVQAA+EDGYRVF EL+PHPLLTHAV+QTAR+LDMS AALAGMRREQ +P+G Sbjct: 789 RHTVRFAAAVQAALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHG 848 Query: 843 LRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHP 902 LR L DL++AGAA+DFA LYP GRL++APLP W H RL +D +R A TV VHP Sbjct: 849 LRALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHP 906 Query: 903 LLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXX 962 LLGSHVRL EEPERH+WQG+VGT WLADHQ+H AALPGAAYCEM Sbjct: 907 LLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLGEA 966 Query: 963 XXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAE--DD 1020 I FEQMLLL ETPI A+V+APGV+ V+ + DG R A LH DD Sbjct: 967 SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSHDGRYTRQLAAVLHVVREADD 1026 Query: 1021 CP--PPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAE 1078 P PP +IA LL +HP+ V+G ++R+ +RG + TVLAE Sbjct: 1027 APDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAE 1086 Query: 1079 VALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRN 1138 V LP +R Q +Y +HP LLDACFQSV A A + + GLLLPLGVR LR Y R+ Sbjct: 1087 VNLPGPLRSQVKAYGVHPVLLDACFQSVAAH-PAVQGMADGGLLLPLGVRRLRSYGSARH 1145 Query: 1139 ARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIG 1198 ARYC T +T G EADLDVLDEHGAV+LAVRGL +GTG ++ E R L ERLL+I Sbjct: 1146 ARYCCTTVTACGV-GVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGERLLSIE 1204 Query: 1199 WQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDD 1258 W +R LPE+ H EPG+WLLI T +A+ D+ A+ LTDALK + Q CT +SW + D Sbjct: 1205 WHERELPENSHAEPGAWLLISTCDAT---DLVAAQLTDALKVHDAQ---CTTMSWPQRAD 1258 Query: 1259 PVVSRERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 RL QL G GV +L P+ G PD +S + E V+H+VRI RE+ E+ + Sbjct: 1259 HAAQAARLRDQLGTGGFTGVFVLTAPQTGDPDAESPVRGGELVKHVVRIAREIPEITAQE 1318 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRL+V+T AQ V SGD NLEQ G+RGLLRVI +EHP L+ + VDVDE T E VA+QL Sbjct: 1319 PRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGAESVARQL 1378 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 L+ S EDETAWRN WY ARL P+PL E+R+T V++ G+R+ +R PGDLQ+LE A Sbjct: 1379 LAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAGMRLQIRTPGDLQTLEFAA 1438 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EVAV+ SSINFADVL+ FGR+ +D R PQLG DF Sbjct: 1439 FDRVPPGPGEIEVAVTASSINFADVLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSEL 1498 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 ++GDRVGG S GCW TF+TCDA LA LP GLTD Q WYGL DLA IK Sbjct: 1499 KVGDRVGGMSPNGCWATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKA 1558 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 GDKVLIHSATGGVGQAAI+IARA GA+I+ATAGN +R +L D+GIEHVYDSRSVEFAEQ Sbjct: 1559 GDKVLIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ 1618 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IRRDT GYGVDIVLNS+TGAAQ AGL+LL GGRF+EIGK D+Y NTRL L PFRR L F Sbjct: 1619 IRRDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELLPFRRNLAF 1678 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y LDL LMSV+ P VRELL+TV+ LT +GVL P+ THYPL +AA AIR M AEHTGK Sbjct: 1679 YGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPLAEAATAIRVMGAAEHTGK 1738 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 L+LD+P G SV +PPEQA V+R DGSYIIT F A K+A AG GRIVL++RS Sbjct: 1739 LILDVPHAGRSSVVLPPEQARVFRSDGSYIITGGLGGLGLFLAEKMANAGAGRIVLSSRS 1798 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 QP+ KA +TIE + A G+D+VVECG+IA+P TADRLV AATATGLPLRGVLH+AAVVEDA Sbjct: 1799 QPSQKALETIELVRAIGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDA 1858 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELI+RDW+PK YG+W LH AT QPLDWFC FSS AAL+GSPGQGAYAAANSW Sbjct: 1859 TLANITDELIERDWAPKAYGAWQLHRATADQPLDWFCSFSSAAALVGSPGQGAYAAANSW 1918 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQ LP ++IAWGAWG++GRA AE I P+EGAYAFE L+R++R YS Sbjct: 1919 LDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAPEEGAYAFETLLRHNRAYS 1978 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P++G+PWL + SP+AE F S GQ G SKF EL+ LP++EW RLRRLL +Q Sbjct: 1979 GYAPVIGSPWLTAFAQHSPFAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQ 2038 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRRTID DR EYGLDSL E+R +E+ETGIR++ I N T R LA + D Sbjct: 2039 VGLILRRTIDTDRLLSEYGLDSLSSQELRARVEAETGIRISATEI--NTTVRGLADLMCD 2096 Query: 2097 TLAEEEGVAAPA 2108 LA + APA Sbjct: 2097 KLAADRDAPAPA 2108 >tr|A5WML4|A5WML4_MYCTF Tax_Id=336982 SubName: Full=Polyketide synthase pks5;[Mycobacterium tuberculosis] Length = 2108 Score = 2454 bits (6359), Expect = 0.0 Identities = 1267/2112 (59%), Positives = 1507/2112 (71%), Gaps = 21/2112 (0%) Query: 3 TSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRS 62 T VTP+AVIGMGCRLPGGI+SPD+LWE+LLRGD+LVTE+P DRWD+D++YDPEPGVPGR+ Sbjct: 12 TRVTPVAVIGMGCRLPGGIDSPDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRT 71 Query: 63 VSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA 122 +WG +LD+V FD EFFGI E+EA +IDPQ RLLLETSWEA+E GGL P +A S T Sbjct: 72 DCKWGAYLDNVGDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTG 130 Query: 123 VFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLM 182 VF GL H DY+++ PY TG N ASGR+++ +GL GPA+T DTACSSGL Sbjct: 131 VFVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTACSSGLT 190 Query: 183 AVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSE 242 A+HLACRSLHDGESD+ALAGG V+LEP + SA GMLS+TGRC +F ADGFV E Sbjct: 191 AIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATGRCHAFDVSADGFVSGE 250 Query: 243 GCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXE 302 GC M+ LKRLPDAL DG+RI A+I GTA NQDG T + PS + Sbjct: 251 GCVMLALKRLPDALADGDRILAVIRGTAANQDGHTVNIATPSRSAQVAAYREALDVAGVD 310 Query: 303 PETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAI 362 P T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ ++AG +GL+KA+ Sbjct: 311 PATVGMVEAHGPGTPVGDPIEYASLAEVYGNDGPCALASVKTNFGHTQSAAGALGLMKAV 370 Query: 363 LSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV 422 L+L++G+VP LHF L D L IET LFVPQE+TPWP TP+R AVSS+GM+GTNV Sbjct: 371 LALQHGVVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV 430 Query: 423 HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS 482 H IVE+AP A P +P T G LF LS++S ALR+TA +LA WV+ Sbjct: 431 HAIVEQAPVPAPESGAPGDTPATPGID-GALLFALSASSQDALRQTAARLADWVDAQGPE 489 Query: 483 VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVF 542 + +DLAYTLAR R HRPVRTAV+AA EL E L E+A G+ Y VG DRGPVWVF Sbjct: 490 LAPADLAYTLARRRGHRPVRTAVLAATTAELTEALREVATGEPPYPPAVGQDDRGPVWVF 549 Query: 543 SGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSV 602 SGQGSQWA MG LLA EPVFAATI +EP+IAAES FSVTEA+TAPE VTGID+VQP++ Sbjct: 550 SGQGSQWAGMGADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTL 609 Query: 603 FAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAG 662 FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS LM R+AG Sbjct: 610 FAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRIAG 668 Query: 663 SGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMA 722 +GAM SVELPA+QV SELMARG++D V++VVASPQSTVIGGAT+TVRDL+A WEQRDV+A Sbjct: 669 AGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRDLVAAWEQRDVLA 728 Query: 723 REVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNL 782 REVAVDVASHS QV + P++PYYSAT FDPRE P C+ YWVDNL Sbjct: 729 REVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYYSATSFDPREEPYCDAYYWVDNL 788 Query: 783 RNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG 842 R+TV+FAAAVQAA+EDGYRVF EL+PHPLLTHAV+QTAR+LDMS AALAGMRREQ +P+G Sbjct: 789 RHTVRFAAAVQAALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHG 848 Query: 843 LRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHP 902 LR L DL++AGAA+DFA LYP GRL++APLP W H RL +D +R A TV VHP Sbjct: 849 LRALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHP 906 Query: 903 LLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXX 962 LLGSHVRL EEPERH+WQG+VGT WLADHQ+H AALPGAAYCEM Sbjct: 907 LLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLGEA 966 Query: 963 XXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAE--DD 1020 I FEQMLLL ETPI A+V+APGV+ V+ + DG R A LH DD Sbjct: 967 SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSHDGRYTRQLAAVLHVVREADD 1026 Query: 1021 CP--PPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAE 1078 P PP +IA LL +HP+ V+G ++R+ +RG + TVLAE Sbjct: 1027 APDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAE 1086 Query: 1079 VALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRN 1138 V LP +R Q +Y +HP LLDACFQSV A A + + GLLLPLGVR LR Y R+ Sbjct: 1087 VNLPGPLRSQVKAYGVHPVLLDACFQSVAAH-PAVQGMADGGLLLPLGVRRLRSYGSARH 1145 Query: 1139 ARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIG 1198 ARYC T +T G EADLDVLDEHGAV+LAVRGL +GTG ++ E R L ERLL+I Sbjct: 1146 ARYCCTTVTACGV-GVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGERLLSIE 1204 Query: 1199 WQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDD 1258 W +R LPE+ H EPG+WLLI T +A+ D+ A+ LTDALK + Q CT +SW + D Sbjct: 1205 WHERELPENSHAEPGAWLLISTCDAT---DLVAAQLTDALKVHDAQ---CTTMSWPQRAD 1258 Query: 1259 PVVSRERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 RL QL G GV +L P+ G PD +S + E V+H+VRI RE+ E+ + Sbjct: 1259 HAAQAARLRDQLGTGGFTGVFVLTAPQTGDPDAESPVRGGELVKHVVRIAREIPEITAQE 1318 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRL+V+T AQ V SGD NLEQ G+RGLLRVI +EHP L+ + VDVDE T E VA+QL Sbjct: 1319 PRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGAESVARQL 1378 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 L+ S EDETAWRN WY ARL P+PL E+R+T V++ G+R+ +R PGDLQ+LE A Sbjct: 1379 LAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAGMRLQIRTPGDLQTLEFAA 1438 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EVAV+ SSINFADVL+ FGR+ +D R PQLG DF Sbjct: 1439 FDRVPPGPGEIEVAVTASSINFADVLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSEL 1498 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 ++GDRVGG S GCW TF+TCDA LA LP GLTD Q WYGL DLA IK Sbjct: 1499 KVGDRVGGMSPNGCWATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKA 1558 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 GDKVLIHSATGGVGQAAI+IARA GA+I+ATAGN +R +L D+GIEHVYDSRSVEFAEQ Sbjct: 1559 GDKVLIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ 1618 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IRRDT GYGVDIVLNS+TGAAQ AGL+LL GGRF+EIGK D+Y NTRL L PFRR L F Sbjct: 1619 IRRDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELLPFRRNLAF 1678 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y LDL LMSV+ P VRELL+TV+ LT +GVL P+ THYPL +AA AIR M AEHTGK Sbjct: 1679 YGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPLAEAATAIRVMGAAEHTGK 1738 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 L+LD+P G SV +PPEQA V+R DGSYIIT F A K+A AG GRIVL++RS Sbjct: 1739 LILDVPHAGRSSVVLPPEQARVFRSDGSYIITGGLGGLGLFLAEKMANAGAGRIVLSSRS 1798 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 QP+ KA +TIE + A G+D+VVECG+IA+P TADRLV AATATGLPLRGVLH+AAVVEDA Sbjct: 1799 QPSQKALETIELVRAIGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDA 1858 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELI+RDW+PK YG+W LH AT QPLDWFC FSS AAL+GSPGQGAYAAANSW Sbjct: 1859 TLANITDELIERDWAPKAYGAWQLHRATADQPLDWFCSFSSAAALVGSPGQGAYAAANSW 1918 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQ LP ++IAWGAWG++GRA AE I P+EGAYAFE L+R++R YS Sbjct: 1919 LDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAPEEGAYAFETLLRHNRAYS 1978 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P++G+PWL + SP+AE F S GQ G SKF EL+ LP++EW RLRRLL +Q Sbjct: 1979 GYAPVIGSPWLTAFAQHSPFAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQ 2038 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRRTID DR EYGLDSL E+R +E+ETGIR++ I N T R LA + D Sbjct: 2039 VGLILRRTIDTDRLLSEYGLDSLSSQELRARVEAETGIRISATEI--NTTVRGLADLMCD 2096 Query: 2097 TLAEEEGVAAPA 2108 LA + APA Sbjct: 2097 KLAADRDAPAPA 2108 >tr|A2VI44|A2VI44_MYCTU Tax_Id=348776 SubName: Full=Polyketide synthase pks5;[Mycobacterium tuberculosis C] Length = 2108 Score = 2452 bits (6356), Expect = 0.0 Identities = 1266/2112 (59%), Positives = 1507/2112 (71%), Gaps = 21/2112 (0%) Query: 3 TSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRS 62 T VTP+AV+GMGCRLPGGI+SPD+LWE+LLRGD+LVTE+P DRWD+D++YDPEPGVPGR+ Sbjct: 12 TRVTPVAVMGMGCRLPGGIDSPDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRT 71 Query: 63 VSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTA 122 +WG +LD+V FD EFFGI E+EA +IDPQ RLLLETSWEA+E GGL P +A S T Sbjct: 72 DCKWGAYLDNVGDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTG 130 Query: 123 VFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLM 182 VF GL H DY+++ PY TG N ASGR+++ +GL GPA+T DTACSSGL Sbjct: 131 VFVGLVHTDYILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTACSSGLT 190 Query: 183 AVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSE 242 A+HLACRSLHDGESD+ALAGG V+LEP + SA GMLS+TGRC +F ADGFV E Sbjct: 191 AIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATGRCHAFDVSADGFVSGE 250 Query: 243 GCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXE 302 GC M+ LKRLPDAL DG+RI A+I GTA NQDG T + PS + Sbjct: 251 GCVMLALKRLPDALADGDRILAVIRGTAANQDGHTVNIATPSRSAQVAAYREALDVAGVD 310 Query: 303 PETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAI 362 P T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ ++AG +GL+KA+ Sbjct: 311 PATVGMVEAHGPGTPVGDPIEYASLAEVYGNDGPCALASVKTNFGHTQSAAGALGLMKAV 370 Query: 363 LSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV 422 L+L++G+VP LHF L D L IET LFVPQE+TPWP TP+R AVSS+GM+GTNV Sbjct: 371 LALQHGVVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV 430 Query: 423 HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS 482 H IVE+AP A P +P T G LF LS++S ALR+TA +LA WV+ Sbjct: 431 HAIVEQAPVPAPESGAPGDTPATPGID-GALLFALSASSQDALRQTAARLADWVDAQGPE 489 Query: 483 VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVF 542 + +DLAYTLAR R HRPVRTAV+AA EL E L E+A G+ Y VG DRGPVWVF Sbjct: 490 LAPADLAYTLARRRGHRPVRTAVLAATTAELTEALREVATGEPPYPPAVGQDDRGPVWVF 549 Query: 543 SGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSV 602 SGQGSQWA MG LLA EPVFAATI +EP+IAAES FSVTEA+TAPE VTGID+VQP++ Sbjct: 550 SGQGSQWAGMGADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGIDRVQPTL 609 Query: 603 FAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAG 662 FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS LM R+AG Sbjct: 610 FAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLEDGVRVICRRSALMTRIAG 668 Query: 663 SGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMA 722 +GAM SVELPA+QV SELMARG++D V++VVASPQSTVIGGAT+TVRDL+A WEQRDV+A Sbjct: 669 AGAMASVELPAQQVLSELMARGVNDAVVAVVASPQSTVIGGATQTVRDLVAAWEQRDVLA 728 Query: 723 REVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNL 782 REVAVDVASHS QV + P++PYYSAT FDPRE P C+ YWVDNL Sbjct: 729 REVAVDVASHSPQVDPILDELAEALAEISPLQPEIPYYSATSFDPREEPYCDAYYWVDNL 788 Query: 783 RNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYG 842 R+TV+FAAAVQAA+EDGYRVF EL+PHPLLTHAV+QTAR+LDMS AALAGMRREQ +P+G Sbjct: 789 RHTVRFAAAVQAALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHG 848 Query: 843 LRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHP 902 LR L DL++AGAA+DFA LYP GRL++APLP W H RL +D +R A TV VHP Sbjct: 849 LRALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANTVAVHP 906 Query: 903 LLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXX 962 LLGSHVRL EEPERH+WQG+VGT WLADHQ+H AALPGAAYCEM Sbjct: 907 LLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAYCEMALAAARAVLGEA 966 Query: 963 XXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAE--DD 1020 I FEQMLLL ETPI A+V+APGV+ V+ + DG R A LH DD Sbjct: 967 SEVRDIRFEQMLLLDDETPIGVTATVEAPGVVPLTVETSHDGRYTRQLAAVLHVVREADD 1026 Query: 1021 CP--PPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAE 1078 P PP +IA LL +HP+ V+G ++R+ +RG + TVLAE Sbjct: 1027 APDQPPQKNIAELLASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAE 1086 Query: 1079 VALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRN 1138 V LP +R Q +Y +HP LLDACFQSV A A + + GLLLPLGVR LR Y R+ Sbjct: 1087 VNLPGPLRSQVKAYGVHPVLLDACFQSVAAH-PAVQGMADGGLLLPLGVRRLRSYGSARH 1145 Query: 1139 ARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIG 1198 ARYC T +T G EADLDVLDEHGAV+LAVRGL +GTG ++ E R L ERLL+I Sbjct: 1146 ARYCCTTVTACGV-GVEADLDVLDEHGAVVLAVRGLQLGTGASQASERARVLGERLLSIE 1204 Query: 1199 WQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDD 1258 W +R LPE+ H EPG+WLLI T +A+ D+ A+ LTDALK + Q CT +SW + D Sbjct: 1205 WHERELPENSHAEPGAWLLISTCDAA---DLVAAQLTDALKVHDAQ---CTTMSWPQRAD 1258 Query: 1259 PVVSRERLGRQLR--GRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 RL QL G GV +L P+ G PD +S + E V+H+VRI RE+ E+ + Sbjct: 1259 HAAQAARLRDQLGTGGFTGVFVLTAPQTGDPDAESPVRGGELVKHVVRIAREIPEITAQE 1318 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRL+V+T AQ V SGD NLEQ G+RGLLRVI +EHP L+ + VDVDE T E VA+QL Sbjct: 1319 PRLYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQTGAESVARQL 1378 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 L+ S EDETAWRN WY ARL P+PL E+R+T V++ G+R+ +R PGDLQ+LE A Sbjct: 1379 LAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAEAGMRLQIRTPGDLQTLEFAA 1438 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EVAV+ SSINFADVL+ FGR+ +D R PQLG DF Sbjct: 1439 FDRVPPGPGEIEVAVTASSINFADVLVTFGRYQTLDGRQPQLGTDFAGVVSAVGPGVSEL 1498 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 ++GDRVGG S GCW TF+TCDA LA LP GLTD Q WYGL DLA IK Sbjct: 1499 KVGDRVGGMSPNGCWATFVTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKA 1558 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 GDKVLIHSATGGVGQAAI+IARA GA+I+ATAGN +R +L D+GIEHVYDSRSVEFAEQ Sbjct: 1559 GDKVLIHSATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ 1618 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IRRDT GYGVDIVLNS+TGAAQ AGL+LL GGRF+EIGK D+Y NTRL L PFRR L F Sbjct: 1619 IRRDTAGYGVDIVLNSVTGAAQLAGLKLLALGGRFIEIGKRDIYSNTRLELLPFRRNLAF 1678 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y LDL LMSV+ P VRELL+TV+ LT +GVL P+ THYPL +AA AIR M AEHTGK Sbjct: 1679 YGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTHYPLAEAATAIRVMGAAEHTGK 1738 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 L+LD+P G SV +PPEQA V+R DGSYIIT F A K+A AG GRIVL++RS Sbjct: 1739 LILDVPHAGRSSVVLPPEQARVFRSDGSYIITGGLGGLGLFLAEKMANAGAGRIVLSSRS 1798 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 QP+ KA +TIE + A G+D+VVECG+IA+P TADRLV AATATGLPLRGVLH+AAVVEDA Sbjct: 1799 QPSQKALETIELVRAIGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDA 1858 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELI+RDW+PK YG+W LH AT QPLDWFC FSS AAL+GSPGQGAYAAANSW Sbjct: 1859 TLANITDELIERDWAPKAYGAWQLHRATADQPLDWFCSFSSAAALVGSPGQGAYAAANSW 1918 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQ LP ++IAWGAWG++GRA AE I P+EGAYAFE L+R++R YS Sbjct: 1919 LDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGDAIAPEEGAYAFETLLRHNRAYS 1978 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P++G+PWL + SP+AE F S GQ G SKF EL+ LP++EW RLRRLL +Q Sbjct: 1979 GYAPVIGSPWLTAFAQHSPFAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQ 2038 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRRTID DR EYGLDSL E+R +E+ETGIR++ I N T R LA + D Sbjct: 2039 VGLILRRTIDTDRLLSEYGLDSLSSQELRARVEAETGIRISATEI--NTTVRGLADLMCD 2096 Query: 2097 TLAEEEGVAAPA 2108 LA + APA Sbjct: 2097 KLAADRDAPAPA 2108 >tr|A0QF84|A0QF84_MYCA1 Tax_Id=243243 SubName: Full=Mycocerosic acid synthase; EC=2.3.1.111;[Mycobacterium avium] Length = 2098 Score = 2452 bits (6354), Expect = 0.0 Identities = 1267/2104 (60%), Positives = 1515/2104 (72%), Gaps = 27/2104 (1%) Query: 5 VTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVS 64 + P+AVIGM CRLPG ++SP++LWE+LLRGD+ VTE+PPDRWD D++YDPEPGVPGRSVS Sbjct: 1 MVPVAVIGMACRLPGAVDSPERLWEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVS 60 Query: 65 RWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVF 124 RWG F+DDVAGFD EFFGI+EREAT++DPQ RLLLETSWEA+E GL +A S T VF Sbjct: 61 RWGAFIDDVAGFDPEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTGVF 120 Query: 125 TGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMAV 184 GLTH DY +L + Y +G N S+ASGRI++ LG+HGPA+T DTACSSGL A+ Sbjct: 121 IGLTHGDYQLLAADTRSVEGAYGFSGSNFSLASGRIAYALGVHGPALTVDTACSSGLTAI 180 Query: 185 HLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEGC 244 HLACRSLH+GESDLALAGG + L+P A SA+GMLS TGRC +F ADGFV EG Sbjct: 181 HLACRSLHEGESDLALAGGATLALDPRKFSAGSAEGMLSPTGRCHAFDVAADGFVGGEGS 240 Query: 245 AMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEPE 304 M+LLKRL DALRDG+RI A++ GTA NQDG T + PS+ + Sbjct: 241 VMLLLKRLNDALRDGDRILAVVRGTAANQDGHTVNIATPSKTAQTAVYRAALAAAGVDAG 300 Query: 305 TIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAILS 364 T+G+VEAHG GTP+GDPIEY SLA VYG PCAL S K+N GH+ A++G +G++KAIL+ Sbjct: 301 TVGMVEAHGPGTPVGDPIEYASLAEVYGIDGPCALASVKTNFGHAQAASGALGMMKAILA 360 Query: 365 LRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVHV 424 L++G+VP LHF +L DDL I+T LFVPQ+ TPW G + P+R AVSS+G+SGTNVH Sbjct: 361 LQHGVVPRNLHFTQLPDDLARIDTKLFVPQQTTPWVSNGGH-PRRAAVSSYGLSGTNVHA 419 Query: 425 IVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDSVV 484 I+E+AP A PET G + LF LSSTS LR TA +LA WV H D + Sbjct: 420 ILEQAPEPA-----PETVAPEGISAESPLLFPLSSTSADELRRTAGRLADWVHAHGD-LA 473 Query: 485 LSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVFSG 544 L DLAYTLAR R HRPVRTAV+A D +L+E L E+ADGD Y A VG GDRGPVWVFSG Sbjct: 474 LPDLAYTLARRRVHRPVRTAVLAGDRAQLIEALREVADGDTPYPAAVGRGDRGPVWVFSG 533 Query: 545 QGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSVFA 604 QGSQWA+MG LLA EPVFAAT+ + EP+IA ES FSV EA++AP+TVTG D+VQP++F Sbjct: 534 QGSQWAAMGADLLATEPVFAATVAQAEPLIARESGFSVAEAMSAPQTVTGQDRVQPTLFT 593 Query: 605 VQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAGSG 664 +QVALA TM+ +GVRPGAVIGHS+ D ARVICRRS+LM+RVAG+G Sbjct: 594 MQVALAATMK-AHGVRPGAVIGHSLGEAAAAVVAGALSLEDGARVICRRSRLMSRVAGTG 652 Query: 665 AMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMARE 724 A SVELPA+QV SEL ARGI DVV++VVASPQSTVI GA TVRDL+ W++R VMARE Sbjct: 653 ATASVELPAQQVLSELTARGISDVVVAVVASPQSTVIAGAAPTVRDLVTAWQERGVMARE 712 Query: 725 VAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNLRN 784 V DVA HS QV P+VPYYSATLFDPRE PVC+ YW +N+R Sbjct: 713 VPTDVAFHSPQVDPIMDDLTDALAEISPRPPEVPYYSATLFDPREQPVCDARYWANNMRR 772 Query: 785 TVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLR 844 V+FA AVQAA+EDGYRVFAEL+PHPLL A+EQTAR+ ++ +AALAGMRR Q++P+GLR Sbjct: 773 MVRFATAVQAALEDGYRVFAELAPHPLLVRALEQTARSREIPMAALAGMRRGQALPHGLR 832 Query: 845 GLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHPLL 904 G +ADLH+AGAA+DF+ LYP GRL+DAPLP WTH RL++ G E G CTV VHPLL Sbjct: 833 GFVADLHNAGAAVDFSVLYPTGRLVDAPLPTWTHRRLWLTDGGLESPTHGGCTVAVHPLL 892 Query: 905 GSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXXXX 964 G HV L EEPERH+WQ DVGTAA WLADHQ+ NV LPGAAYCEM Sbjct: 893 GPHVHLQEEPERHLWQADVGTAAQPWLADHQIRNVVVLPGAAYCEMALAAARSVLGATAE 952 Query: 965 XXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDDCPPP 1024 I FEQ LLL +T +DA ASV +PGV++F VQ++Q GE+ R+A+A L AA D+ P Sbjct: 953 VRDIRFEQALLLDEQTTVDASASVSSPGVLHFTVQSHQGGEQARHASAVLGAATDE-QPA 1011 Query: 1025 AYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVALPAS 1084 A+D++ALL AHP+ +G ++R RGVQ +GTVLAEVALP Sbjct: 1012 AHDLSALLTAHPHDDDGDEVRRRMDRRGVQYGPAFAGLGAVHSGDE-TGTVLAEVALPRQ 1070 Query: 1085 IRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNARYCYT 1144 IR QQ++Y HPALLDACFQSV A +G A L L LG+R LR Y RNA YCYT Sbjct: 1071 IRSQQAAYGAHPALLDACFQSVEAHPAVRALGDGA-LGLVLGIRRLRAYGAARNAHYCYT 1129 Query: 1145 RLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQQRTL 1204 R+TK + G EAD+DVLDEHGAVLLAV+GL +GT +E G DR L+ERLL I W+QR L Sbjct: 1130 RVTKADTSGVEADIDVLDEHGAVLLAVQGLRVGTSASESGTRDRVLTERLLNIEWRQREL 1189 Query: 1205 PESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPVVSRE 1264 PE H + SWLLI T +A D+ ASTL D LK++G Q CT ++W Q D E Sbjct: 1190 PEPEHADAASWLLIGT---TATADVLASTLADTLKNHGAQ---CTTMAWPQQADHTAHAE 1243 Query: 1265 RLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLFVV 1322 +L Q RG GVV+L GP+ G D++S L +R+ V+HLVRI REL +L GE PRL+VV Sbjct: 1244 QLRNQWRGDGFTGVVVLTGPKNGDNDQESALLSRDHVQHLVRIARELTDLPGEPPRLYVV 1303 Query: 1323 TRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGSEE 1382 TR AQ V D NL QAGLRGL+RVI EHP L +DVDE TD + +A+QLL+GSEE Sbjct: 1304 TRNAQTVLPNDVPNLGQAGLRGLVRVIGMEHPQLGAGQIDVDESTDAQALARQLLAGSEE 1363 Query: 1383 DETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRVPP 1442 DETAWR+G WY ARL P+PL E+R T V N E DG+R+ +R PGDL+SLELVA DR+PP Sbjct: 1364 DETAWRDGAWYTARLCPAPLLPEERHTAVANHECDGMRLQIRTPGDLESLELVACDRIPP 1423 Query: 1443 GPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQIGDRV 1502 GPGQ+EVAVS SSINFADVL+AFGR+P + R P+LG DF H++GD V Sbjct: 1424 GPGQIEVAVSASSINFADVLVAFGRYPAFEGRLPELGTDFAGVVTAVGPDVTDHKVGDHV 1483 Query: 1503 GGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGDKVLI 1562 GG S GCW TFLTCDA LAVTLP GL D+Q +YGL++LA I GD+VLI Sbjct: 1484 GGLSANGCWGTFLTCDARLAVTLPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLI 1543 Query: 1563 HSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRDTD 1622 HSATGGVGQAAI+IARA GAEIFATAG+ +R +L D+GIEHVYDSR+VEFA+ IR DTD Sbjct: 1544 HSATGGVGQAAIAIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFADLIRHDTD 1603 Query: 1623 GYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLDLA 1682 GYGVDIVLNS+TGAAQRAG+ELL FGGRFVEIGK D+YG+TRLGL PFRR LTFY LDLA Sbjct: 1604 GYGVDIVLNSVTGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLLPFRRNLTFYALDLA 1663 Query: 1683 LMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDIP 1742 LMS + PDR+R LL TV+ LTADG L PE THYPL DAA+AIR MS A+HTGKLVLD+P Sbjct: 1664 LMSFSHPDRLRGLLRTVYRLTADGALPMPESTHYPLADAASAIRVMSAAQHTGKLVLDVP 1723 Query: 1743 RTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLA----EAGCGRIVLTARSQP 1798 G V VPP Q +R DG+YI+T F A K+A AGCGRIVL +R+ P Sbjct: 1724 HAGRSRVVVPPAQVRAFRSDGAYIVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALP 1783 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 NPKA T+ER+ GADIVVE G+IAE TA RL++ ATATGLP+RGVLH AAV+EDATL Sbjct: 1784 NPKALATLERIRQMGADIVVERGDIAEAGTAQRLLDVATATGLPVRGVLHLAAVIEDATL 1843 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCAT----IGQPLDWFCLFSSGAALLGSPGQGAYAAAN 1914 NITDELI+RDW+ KVYG+WNLHCA Q LDWFC FSS AAL+GSPGQGAYAAAN Sbjct: 1844 ANITDELIERDWAAKVYGAWNLHCALQESGAEQSLDWFCSFSSAAALVGSPGQGAYAAAN 1903 Query: 1915 SWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRP 1974 SW+D F WRRA+GL +AIAWGAW ++GR LA+ ++ ITPDEGAYAFE L+R+DR Sbjct: 1904 SWLDAFTRWRRARGLKATAIAWGAWAQIGRGAALADSADVAITPDEGAYAFEALLRHDRA 1963 Query: 1975 YSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLV 2034 +GY PI G PWL +RSP+AE F + GQ + G SK R EL LP +EWS RLRRL+ Sbjct: 1964 CTGYAPITGTPWLTAFAQRSPFAEAFRANGQSATGTSKLRAELEELPPEEWSTRLRRLIS 2023 Query: 2035 EQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYL 2094 +Q S+ILRR +D DR EYGLDSLG LE+ T I++ETGIR++P IA T R LA L Sbjct: 2024 DQVSLILRRNVDPDRPLPEYGLDSLGGLELLTRIQTETGIRVSPADIAAIGTIRGLADLL 2083 Query: 2095 ADTL 2098 D L Sbjct: 2084 RDKL 2087 >tr|B2HQ50|B2HQ50_MYCMM Tax_Id=216594 (pks5_1)SubName: Full=Polyketide synthase, Pks5_1;[Mycobacterium marinum] Length = 2084 Score = 2432 bits (6304), Expect = 0.0 Identities = 1256/2112 (59%), Positives = 1528/2112 (72%), Gaps = 33/2112 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 ++ VTP+AVIGM CRLP GI+SP+K W +LLRGD+L+TE+P DRWD D++YDPEPGVP Sbjct: 3 KSHVTPVAVIGMACRLPKGIDSPEKFWTALLRGDDLITEIPADRWDADEYYDPEPGVPDH 62 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 SVSRWGGFLDDVAGFD EFFGISEREA +IDPQ RLLL+TSWEA+E G+ P SL+GS T Sbjct: 63 SVSRWGGFLDDVAGFDPEFFGISEREAIAIDPQHRLLLQTSWEAVEHAGMPPMSLSGSLT 122 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF G+ H+DY +T AG L Y TG S+ASGR+S+ LGL GPAMT DTACSS L Sbjct: 123 GVFVGMCHDDYAFVTDDAGALGDAYAFTGTAFSMASGRVSYALGLRGPAMTVDTACSSSL 182 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 +AVH+ACRSL GES+LALAGGC ++LEP +ASAQGMLS TGRC++F A ADGFVRS Sbjct: 183 LAVHMACRSLDGGESELALAGGCMLMLEPDVFSSASAQGMLSPTGRCRTFDASADGFVRS 242 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGCAM++LKRLPDA+RDG+R+ A++ G+ATNQDG T+ + PS D Sbjct: 243 EGCAMLVLKRLPDAVRDGDRVLAVLRGSATNQDGRTDNISTPSPDAQVAAYRAALAVAGV 302 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGA-GTPCALGSAKSNMGHSTASAGTVGLIK 360 + +T+G++EAHGTGTP+GDPIE+ SLA+VYG+ G PCA+GSAKS++GH+ A+AG VG+IK Sbjct: 303 DADTVGMIEAHGTGTPVGDPIEFSSLAQVYGSNGNPCAVGSAKSSVGHTEAAAGAVGIIK 362 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 A+LSL++GLVPP++H RL D+L EI++ LFVPQ +TPWP G TP+R AVSS+GMSG+ Sbjct: 363 AVLSLQHGLVPPMVHHTRLPDELAEIDSALFVPQAITPWPEGNDRTPRRAAVSSYGMSGS 422 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVHVI+E+AP A + + G GDA LF +S++S ALR+TA +LA WV+ H+ Sbjct: 423 NVHVILEQAPEPAVCRN---GAAGLGDAL----LFTVSASSTEALRQTADRLADWVDNHE 475 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 S SDLAYTLAR R+H+PVR +VA + EL L E A GD Y A VGH D GPVW Sbjct: 476 ISP--SDLAYTLARRRSHQPVRAGLVAGNRTELAHRLRETAAGDTPYPAAVGHDDLGPVW 533 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA+MG LLANEPVFAAT+ +LEP+IAAES FSVTEA+TA E VTGID+VQP Sbjct: 534 VFSGQGSQWATMGADLLANEPVFAATVAELEPLIAAESGFSVTEAMTAMEPVTGIDRVQP 593 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FA+QVALA TM ++YGV PGAVIGHS+ D +VICRRS+L R+ Sbjct: 594 TLFAIQVALAQTM-RSYGVHPGAVIGHSLGEVAAAVVAGALLLADGVKVICRRSRLCTRL 652 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELPA +V +L+ DVV++VVASPQSTVIGGAT+TVR+L+A W +R+V Sbjct: 653 AGSGAMASVELPAARVREDLVRHRAKDVVVAVVASPQSTVIGGATDTVRELVAAWGEREV 712 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASH+ QV + P++PYYSAT FDPRE P C+ YWVD Sbjct: 713 MAREVAVDVASHTPQVEPILGELSELLADVEPLAPQLPYYSATSFDPRERPRCDARYWVD 772 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR+ V+F+AAV+AA++DGYRVF ELSPHPLLT AVEQTA +LD+ AAL MRR Q +P Sbjct: 773 NLRHAVRFSAAVRAALDDGYRVFGELSPHPLLTRAVEQTAASLDIPAAALPAMRRNQPLP 832 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRGL+ADLHSAGAA+DFA LYP G+L+DAPLPVW + RL + T +R A +V Sbjct: 833 HGLRGLVADLHSAGAAVDFATLYPDGQLVDAPLPVWANRRLLLAT-ADARRHGCANSVAA 891 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH WQ ++GTA L WL DHQV++VAALPGAAYCEM Sbjct: 892 HPLLGAHVDLLEEPERHAWQSEIGTATLPWLGDHQVNSVAALPGAAYCEMALAAANTVFG 951 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I F +MLLL +T A+A V+APG+ +F V + GEK+R +TA L A E D Sbjct: 952 NPSEVGDIGFHEMLLLDDQTAAGAVALVEAPGIASFAVDTVRGGEKVRRSTALLRAVERD 1011 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 P YDI ALL AH ++G +LRE FA+ G+ S VLAE++ Sbjct: 1012 SQPAGYDIEALLAAHACRLDGDELREWFAKTGIHYGPAFTGLAAAHVCERGSDAVLAEIS 1071 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP S+R QQ+ Y +HPALLDACFQSV A ++G+ GLLLPLGVR LR + TRNAR Sbjct: 1072 LPGSMRTQQAGYLVHPALLDACFQSVLAHPVVREMGN-GGLLLPLGVRRLRSHASTRNAR 1130 Query: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 +CYTR+T EAD+DVLDEHG VLLAVRGL MGTG +E + DR +S LL WQ Sbjct: 1131 FCYTRVTACG-HDAEADIDVLDEHGTVLLAVRGLLMGTGLSELADQDRLMSRHLLGTEWQ 1189 Query: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV 1260 QR LP+ P SWLL+ S D + L +ALKS GT +C SW +Q D + Sbjct: 1190 QRELPQPQAPNPESWLLV---GISETADRLTTRLAEALKSLGT---DCITTSWHLQADHI 1243 Query: 1261 VSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPR 1318 ER QLR GVV++ G +P + VRH+VR++REL E+ GE PR Sbjct: 1244 TDAERFRDQLRDHRFAGVVVMTGTGCSSP------VTSDYVRHVVRVVRELPEIMGEAPR 1297 Query: 1319 LFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLS 1378 LFVVTR AQ V G++ANLEQAGLRGLLRVI +E+P L TT VDVDEH+ E VA+QLLS Sbjct: 1298 LFVVTRGAQTVLGGESANLEQAGLRGLLRVIGAEYPHLHTTHVDVDEHSGSEVVARQLLS 1357 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GSEEDETAWR G WY ARL+P PL E+R+T V+ + +G+R+ +R PGDLQ++E VA D Sbjct: 1358 GSEEDETAWRCGQWYTARLSPMPLRPEERKTTVVEHDTEGMRLQIRTPGDLQTMEFVAFD 1417 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RV PGPGQ+EVAVS SSINFADVL++FGR+ D + PQLG DF HQ+ Sbjct: 1418 RVAPGPGQIEVAVSTSSINFADVLVSFGRYNSPDGQMPQLGTDFAGVVTAVGPDVTDHQV 1477 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GDRVGG S GCW TF+TCD LA +P+GLTD Q WYGL+DL I+ GD Sbjct: 1478 GDRVGGMSPHGCWATFVTCDGALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGD 1537 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA GAEI+ATAG+P +R +L D+GIEHVYDSRS+EFAE IR Sbjct: 1538 KVLIHSGTGGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRSIEFAEAIR 1597 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVDIVLNSLTGAAQRAGLELL +GGRFVEIGK D+YG+T++GLFPFRR L+FY Sbjct: 1598 ADTDGYGVDIVLNSLTGAAQRAGLELLAWGGRFVEIGKRDIYGDTKMGLFPFRRNLSFYG 1657 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DL ++S+T P +RELL TV+ TA+GVL P+ THYPL +AA AIR M A+HTGKL+ Sbjct: 1658 VDLGMLSITHPRLIRELLTTVYQHTAEGVLPMPQDTHYPLAEAATAIRVMGAADHTGKLL 1717 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LDIPR+G +V +PPEQ PV R DGSYIIT F A K+A AG GRIVL++RS P Sbjct: 1718 LDIPRSGRSAVVLPPEQVPVLRADGSYIITGGLGGLGLFLAEKMATAGAGRIVLSSRSAP 1777 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 + KA +TIE + + G+D+VVECG+IA+P TA RLV ATAT LPLRGVLH+AAVVEDATL Sbjct: 1778 SQKALETIELIRSIGSDVVVECGDIAQPATAARLVANATATNLPLRGVLHAAAVVEDATL 1837 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 NITDEL+DRDW+PKVYG+W+LH AT QPLDWFC FSS AA+LGSPGQGAYAAANSW+D Sbjct: 1838 ANITDELLDRDWAPKVYGAWHLHQATTDQPLDWFCSFSSAAAMLGSPGQGAYAAANSWLD 1897 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 F HWR Q P +AIAWG W E+GRA LAE + I PDEGAYAF+ L+R++R Y+GY Sbjct: 1898 AFTHWRHNQNQPATAIAWGPWAEIGRAIALAESSDAAIAPDEGAYAFQTLLRHNRTYTGY 1957 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PILG PW+ +L RRS +AE F G S+ R EL LP DEW RLRRL+ EQ S Sbjct: 1958 TPILGTPWIANLARRSRFAEAFRYDGVQRSERSQLRAELAELPLDEWPTRLRRLISEQVS 2017 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 +ILRRTID DR +YGLDSLG LE+RT IE+ETGIR++ I T R LA +L L Sbjct: 2018 LILRRTIDPDRPLTDYGLDSLGNLELRTRIETETGIRISSTDI---TTVRGLADHLCKKL 2074 Query: 2099 AEEEGVAAPAAM 2110 E APA M Sbjct: 2075 TPAED--APATM 2084 >tr|Q1B7A8|Q1B7A8_MYCSS Tax_Id=164756 SubName: Full=Acyl transferase region;[Mycobacterium sp.] Length = 2085 Score = 2404 bits (6230), Expect = 0.0 Identities = 1235/2110 (58%), Positives = 1506/2110 (71%), Gaps = 32/2110 (1%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ++ VTPIAVIGM CRLPGGI+SP++LWE+LLRGD+ VTEVP DRWD D++YDPEPGVPG Sbjct: 2 VDAPVTPIAVIGMACRLPGGIDSPERLWEALLRGDDFVTEVPLDRWDADEYYDPEPGVPG 61 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVS+WG FLDDVAGFDAEFFGISEREAT+IDPQ RLLLET+WEA+E G+DPA+L S Sbjct: 62 RSVSKWGAFLDDVAGFDAEFFGISEREATAIDPQHRLLLETAWEAVEHAGIDPAALHESL 121 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 T VF G+TH DY ++ A + PY TG N S+ASGRIS+ +GLHGPA T D+ACSS Sbjct: 122 TGVFIGMTHGDYQLVAADANAIEGPYGFTGNNYSLASGRISYAMGLHGPAYTVDSACSSS 181 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 L+AVH+ACRSLHDGESD+ALAGG +++LEP + SAQGMLS TGRC +F DADGFV Sbjct: 182 LLAVHMACRSLHDGESDMALAGGVSIMLEPRKMSSGSAQGMLSPTGRCHAFDVDADGFVS 241 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 E +++ KRL DA RDG+RI A++ G+A NQDG T + PS + Sbjct: 242 GEASVVLMFKRLADAQRDGDRILAVVKGSAANQDGHTVNIATPSRNAQVSVYRAALAAAG 301 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +P T+G+VEAHGTGTP+GDPIEY LA VYG PCALGS K+N GH +++G +GL+K Sbjct: 302 MDPATVGMVEAHGTGTPVGDPIEYAGLAEVYGIDAPCALGSVKTNFGHGQSASGAIGLMK 361 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSL++ VP LH+ R+ D++ + T LFVPQE+TPWP G P+R AVSS+G+SGT Sbjct: 362 AILSLQHATVPQNLHYTRMPDEMARVSTNLFVPQEITPWPRG--EQPRRAAVSSYGLSGT 419 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH ++E+AP EA AP V T LF LS+TS LR TA +LA WV+ Sbjct: 420 NVHAVLEQAP-EAPAPVVEPTDKA--------MLFPLSATSAEELRRTAARLADWVDAQS 470 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D L DLAYTLAR R HRPVRT+V AA EL++ L EIADG+ Y+ V G+RGPVW Sbjct: 471 DGD-LRDLAYTLARRRGHRPVRTSVSAATREELIKALREIADGETPYEPAVAKGERGPVW 529 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA MG LLA EPVFAA + +LEP+IA ES FSVTEA++APE VTGID+VQP Sbjct: 530 VFSGQGSQWAGMGKGLLATEPVFAAAVAELEPLIARESGFSVTEAMSAPEKVTGIDRVQP 589 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQ+ALA TM+ +YGV PGAVIGHSM D A+VICRRS+LM R+ Sbjct: 590 TVFAVQIALAATMK-SYGVTPGAVIGHSMGESAAAVVAGGLSLEDGAKVICRRSRLMARI 648 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELPA+QV SEL ARGI DVV+SVVASPQSTV+GGA E++R+L+A+W+ R V Sbjct: 649 AGSGAMASVELPAQQVLSELAARGISDVVLSVVASPQSTVVGGAKESIRELVAEWDARGV 708 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV M P++PYYSATL+DPR+ + YWVD Sbjct: 709 MAREVAVDVASHSPQVDPILDELTEVLEDIEPMEPEIPYYSATLYDPRDPAEFDAYYWVD 768 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR+ V+F+AAVQAA+EDG+RVF EL+PHPLLTHAV+QT R+LDMS+AALA MRREQ P Sbjct: 769 NLRHAVRFSAAVQAALEDGFRVFGELAPHPLLTHAVDQTGRSLDMSLAALAAMRREQESP 828 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 GL +AD+H+AG A+DF+ ++P GRL+DAPLP WTH L + DGQEQ QG TV V Sbjct: 829 DGLLSFVADVHNAGGAVDFSVIFPDGRLVDAPLPTWTHVHLMLTRDGQEQ-TQGGSTVAV 887 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HVRL EEPERH+WQ DVGT A WL DHQVHNVAALPGAAYCEM Sbjct: 888 HPLLGAHVRLPEEPERHVWQVDVGTVAQPWLGDHQVHNVAALPGAAYCEMALAASRTVFG 947 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FE MLLL +TP+ ++A+V PGV +FVV+ +G ++R ATA LH + Sbjct: 948 DSAEVRDITFEAMLLLEDQTPVSSVATVKRPGVADFVVETYDEGAEVRRATAVLHGDDTA 1007 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 P AYD+ LL AHP G DL FAERG+ TVLAEVA Sbjct: 1008 EAPAAYDVDELLTAHPERREGADLHSWFAERGISYGQAFSGLVAAHTRDDGGNTVLAEVA 1067 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP SIR QQ +Y IHPALLDACFQ+VGA A + L+LPLGVR L + RNA Sbjct: 1068 LPGSIRSQQGAYGIHPALLDACFQAVGAH-SALQADVTGTLMLPLGVRRLSAHASMRNAH 1126 Query: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 YCY +T + EAD++VLDE GAVLL V GL +G+G T G +R L+ERLLTI W+ Sbjct: 1127 YCYVTVTNVSAAAVEADIEVLDEDGAVLLTVEGLRLGSGATAGGHRERLLNERLLTIDWR 1186 Query: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQ--DD 1258 + PE+ HV+ G WLL+ T + A P+ A+ L+DAL T + W ++ D Sbjct: 1187 TQDRPEADHVDAGRWLLVAT-STDAQPE--AARLSDALSG---ADAHVTTMVWPVEQADH 1240 Query: 1259 PVVSRERLGRQLRGR-DGVVILCGP-RAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 + + + R GVV++ P R A Q +QVRHLVRI REL E+ GE Sbjct: 1241 AATAAQVIDRLTADHHSGVVVVTAPVRTDAAPAQGA----DQVRHLVRIARELPEVPGEP 1296 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRLFV+T AQ V + D ANLEQAGLRGL+RV++ EHP LR T VD+D TD +A QL Sbjct: 1297 PRLFVLTHNAQTVLADDVANLEQAGLRGLMRVLAMEHPALRPTQVDLDPATDAAALAAQL 1356 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 LSGSEEDETAWR GD++VARL SPL E+RRT V+N E DG+R+ +R PGDL+SLEL A Sbjct: 1357 LSGSEEDETAWRGGDFHVARLALSPLRPEERRTTVVNHETDGMRLQIRTPGDLESLELAA 1416 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EV+V+ S++NFADVL+A+GR+P + R P+LG DF H Sbjct: 1417 FDRVPPGPGEIEVSVTASNLNFADVLVAYGRYPSFEGRLPKLGADFAGVVTGVGPGVTEH 1476 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 Q+GDRV G S G W TF+TCDANLAV LP+G+ +++ WYGL+DLA I Sbjct: 1477 QVGDRVAGISANGAWATFVTCDANLAVKLPAGVPEDRAAAVPSAHATAWYGLHDLARIGA 1536 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 DKVLIHSATGGVGQAA++IA+A GAEI+ATAG+P +R +L D+GIEHVYDSRS FA++ Sbjct: 1537 RDKVLIHSATGGVGQAAVAIAKAAGAEIYATAGSPERRKILRDMGIEHVYDSRSTAFADE 1596 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IR DT GYGVDIVLNSL GAAQRAGLELL+FGGRFVEIGK D+YG++++GLFPFRR L F Sbjct: 1597 IREDTAGYGVDIVLNSLPGAAQRAGLELLSFGGRFVEIGKRDIYGDSKMGLFPFRRNLAF 1656 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y +DLAL+++T PD +R LL TV+ ADGVL PE THYPL D A AIR M A HTGK Sbjct: 1657 YAVDLALLTLTNPDILRRLLETVYQQIADGVLPLPETTHYPLADGATAIRVMGAAGHTGK 1716 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 LVLD+P TG + VPPE A V+R DG+Y++T F A K+A AGCGRIVL RS Sbjct: 1717 LVLDVPHTGQSTAVVPPENAEVFRGDGAYVVTGGMGGLGLFLAEKMAAAGCGRIVLNGRS 1776 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 PNP A I+R+ A G ++ V G+IA+P TADR++ AATATGLP+RGVLH+AAVVEDA Sbjct: 1777 APNPAATAAIDRIRAGGTEVEVSLGDIADPATADRVIAAATATGLPVRGVLHAAAVVEDA 1836 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELIDRDW+PKV G+WNLH AT+ QPLDWFC FSS AA++GSPGQGAYAAANSW Sbjct: 1837 TLPNITDELIDRDWAPKVQGAWNLHAATLDQPLDWFCSFSSAAAMVGSPGQGAYAAANSW 1896 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQGLP SAIAWGAW E+G+ +AE + I PD+GA AF+ L+R++R Y Sbjct: 1897 LDAFTHWRRAQGLPASAIAWGAWAEIGKGQGMAEDTAMAILPDDGADAFDELLRHNRGYC 1956 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P+ GAPWL + S +AE F+S GQG G S F EL LPQ+EW GRLR+L+ +Q Sbjct: 1957 GYAPVAGAPWLTAFAQTSKFAEAFASIGQGGTGTSAFLTELFELPQEEWPGRLRKLVADQ 2016 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRR++D+DR EYGLDSLG LE+RT IE+ETGIR+ I T RALAQ LAD Sbjct: 2017 IGLILRRSVDSDRPLSEYGLDSLGTLEVRTRIENETGIRIGSTDI---TTVRALAQRLAD 2073 Query: 2097 TLAEEEGVAA 2106 TLA + G ++ Sbjct: 2074 TLAGDSGTSS 2083 >tr|A1UHR5|A1UHR5_MYCSK Tax_Id=189918 SubName: Full=Acyl transferase domain protein;[Mycobacterium sp.] Length = 2085 Score = 2404 bits (6230), Expect = 0.0 Identities = 1235/2110 (58%), Positives = 1506/2110 (71%), Gaps = 32/2110 (1%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ++ VTPIAVIGM CRLPGGI+SP++LWE+LLRGD+ VTEVP DRWD D++YDPEPGVPG Sbjct: 2 VDAPVTPIAVIGMACRLPGGIDSPERLWEALLRGDDFVTEVPLDRWDADEYYDPEPGVPG 61 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVS+WG FLDDVAGFDAEFFGISEREAT+IDPQ RLLLET+WEA+E G+DPA+L S Sbjct: 62 RSVSKWGAFLDDVAGFDAEFFGISEREATAIDPQHRLLLETAWEAVEHAGIDPAALHESL 121 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 T VF G+TH DY ++ A + PY TG N S+ASGRIS+ +GLHGPA T D+ACSS Sbjct: 122 TGVFIGMTHGDYQLVAADANAIEGPYGFTGNNYSLASGRISYAMGLHGPAYTVDSACSSS 181 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 L+AVH+ACRSLHDGESD+ALAGG +++LEP + SAQGMLS TGRC +F DADGFV Sbjct: 182 LLAVHMACRSLHDGESDMALAGGVSIMLEPRKMSSGSAQGMLSPTGRCHAFDVDADGFVS 241 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 E +++ KRL DA RDG+RI A++ G+A NQDG T + PS + Sbjct: 242 GEASVVLMFKRLADAQRDGDRILAVVKGSAANQDGHTVNIATPSRNAQVSVYRAALAAAG 301 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +P T+G+VEAHGTGTP+GDPIEY LA VYG PCALGS K+N GH +++G +GL+K Sbjct: 302 MDPATVGMVEAHGTGTPVGDPIEYAGLAEVYGIDAPCALGSVKTNFGHGQSASGAIGLMK 361 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSL++ VP LH+ R+ D++ + T LFVPQE+TPWP G P+R AVSS+G+SGT Sbjct: 362 AILSLQHATVPQNLHYTRMPDEMARVSTNLFVPQEITPWPRG--EQPRRAAVSSYGLSGT 419 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH ++E+AP EA AP V T LF LS+TS LR TA +LA WV+ Sbjct: 420 NVHAVLEQAP-EAPAPVVEPTDKA--------MLFPLSATSAEELRRTAARLADWVDAQS 470 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D L DLAYTLAR R HRPVRT+V AA EL++ L EIADG+ Y+ V G+RGPVW Sbjct: 471 DGD-LRDLAYTLARRRGHRPVRTSVSAATREELIKALREIADGETPYEPAVAKGERGPVW 529 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA MG LLA EPVFAA + +LEP+IA ES FSVTEA++APE VTGID+VQP Sbjct: 530 VFSGQGSQWAGMGKGLLATEPVFAAAVAELEPLIARESGFSVTEAMSAPEKVTGIDRVQP 589 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQ+ALA TM+ +YGV PGAVIGHSM D A+VICRRS+LM R+ Sbjct: 590 TVFAVQIALAATMK-SYGVTPGAVIGHSMGESAAAVVAGGLSLEDGAKVICRRSRLMARI 648 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELPA+QV SEL ARGI DVV+SVVASPQSTV+GGA E++R+L+A+W+ R V Sbjct: 649 AGSGAMASVELPAQQVLSELAARGISDVVLSVVASPQSTVVGGAKESIRELVAEWDARGV 708 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV M P++PYYSATL+DPR+ + YWVD Sbjct: 709 MAREVAVDVASHSPQVDPILDELTEVLEDIEPMEPEIPYYSATLYDPRDPAEFDAYYWVD 768 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR+ V+F+AAVQAA+EDG+RVF EL+PHPLLTHAV+QT R+LDMS+AALA MRREQ P Sbjct: 769 NLRHAVRFSAAVQAALEDGFRVFGELAPHPLLTHAVDQTGRSLDMSLAALAAMRREQESP 828 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 GL +AD+H+AG A+DF+ ++P GRL+DAPLP WTH L + DGQEQ QG TV V Sbjct: 829 DGLLSFVADVHNAGGAVDFSVIFPDGRLVDAPLPTWTHVHLMLTRDGQEQ-TQGGSTVAV 887 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HVRL EEPERH+WQ DVGT A WL DHQVHNVAALPGAAYCEM Sbjct: 888 HPLLGAHVRLPEEPERHVWQVDVGTVAQPWLGDHQVHNVAALPGAAYCEMALAASRTVFG 947 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FE MLLL +TP+ ++A+V PGV +FVV+ +G ++R ATA LH + Sbjct: 948 DSAEVRDITFEAMLLLEDQTPVSSVATVKRPGVADFVVETYDEGAEVRRATAVLHGDDTA 1007 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 P AYD+ LL AHP G DL FAERG+ TVLAEVA Sbjct: 1008 EAPAAYDVDELLTAHPERREGADLHSWFAERGISYGQAFSGLVAAHTRDDGGNTVLAEVA 1067 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP SIR QQ +Y IHPALLDACFQ+VGA A + L+LPLGVR L + RNA Sbjct: 1068 LPGSIRSQQGAYGIHPALLDACFQAVGAH-SALQADVTGTLMLPLGVRRLSAHASMRNAH 1126 Query: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 YCY +T + EAD++VLDE GAVLL V GL +G+G T G +R L+ERLLTI W+ Sbjct: 1127 YCYVTVTNVSAAAVEADIEVLDEDGAVLLTVEGLRLGSGATAGGHRERLLNERLLTIDWR 1186 Query: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQ--DD 1258 + PE+ HV+ G WLL+ T + A P+ A+ L+DAL T + W ++ D Sbjct: 1187 TQDRPEADHVDAGRWLLVAT-STDAQPE--AARLSDALSG---ADAHVTTMVWPVEQADH 1240 Query: 1259 PVVSRERLGRQLRGR-DGVVILCGP-RAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 + + + R GVV++ P R A Q +QVRHLVRI REL E+ GE Sbjct: 1241 AATAAQVIDRLTADHHSGVVVVTAPVRTDAAPAQGA----DQVRHLVRIARELPEVPGEP 1296 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRLFV+T AQ V + D ANLEQAGLRGL+RV++ EHP LR T VD+D TD +A QL Sbjct: 1297 PRLFVLTHNAQTVLADDVANLEQAGLRGLMRVLAMEHPALRPTQVDLDPATDAAALAAQL 1356 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 LSGSEEDETAWR GD++VARL SPL E+RRT V+N E DG+R+ +R PGDL+SLEL A Sbjct: 1357 LSGSEEDETAWRGGDFHVARLALSPLRPEERRTTVVNHETDGMRLQIRTPGDLESLELAA 1416 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EV+V+ S++NFADVL+A+GR+P + R P+LG DF H Sbjct: 1417 FDRVPPGPGEIEVSVTASNLNFADVLVAYGRYPSFEGRLPKLGADFAGVVTGVGPGVTEH 1476 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 Q+GDRV G S G W TF+TCDANLAV LP+G+ +++ WYGL+DLA I Sbjct: 1477 QVGDRVAGISANGAWATFVTCDANLAVKLPAGVPEDRAAAVPSAHATAWYGLHDLARIGA 1536 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 DKVLIHSATGGVGQAA++IA+A GAEI+ATAG+P +R +L D+GIEHVYDSRS FA++ Sbjct: 1537 RDKVLIHSATGGVGQAAVAIAKAAGAEIYATAGSPERRKILRDMGIEHVYDSRSTAFADE 1596 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IR DT GYGVDIVLNSL GAAQRAGLELL+FGGRFVEIGK D+YG++++GLFPFRR L F Sbjct: 1597 IREDTAGYGVDIVLNSLPGAAQRAGLELLSFGGRFVEIGKRDIYGDSKMGLFPFRRNLAF 1656 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y +DLAL+++T PD +R LL TV+ ADGVL PE THYPL D A AIR M A HTGK Sbjct: 1657 YAVDLALLTLTNPDILRRLLETVYQQIADGVLPLPETTHYPLADGATAIRVMGAAGHTGK 1716 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 LVLD+P TG + VPPE A V+R DG+Y++T F A K+A AGCGRIVL RS Sbjct: 1717 LVLDVPHTGQSTAVVPPENAEVFRGDGAYVVTGGMGGLGLFLAEKMAAAGCGRIVLNGRS 1776 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 PNP A I+R+ A G ++ V G+IA+P TADR++ AATATGLP+RGVLH+AAVVEDA Sbjct: 1777 APNPAATAAIDRIRAGGTEVEVSLGDIADPATADRVIAAATATGLPVRGVLHAAAVVEDA 1836 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELIDRDW+PKV G+WNLH AT+ QPLDWFC FSS AA++GSPGQGAYAAANSW Sbjct: 1837 TLPNITDELIDRDWAPKVQGAWNLHAATLDQPLDWFCSFSSAAAMVGSPGQGAYAAANSW 1896 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQGLP SAIAWGAW E+G+ +AE + I PD+GA AF+ L+R++R Y Sbjct: 1897 LDAFTHWRRAQGLPASAIAWGAWAEIGKGQGMAEDTAMAILPDDGADAFDELLRHNRGYC 1956 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P+ GAPWL + S +AE F+S GQG G S F EL LPQ+EW GRLR+L+ +Q Sbjct: 1957 GYAPVAGAPWLTAFAQTSKFAEAFASIGQGGTGTSAFLTELFELPQEEWPGRLRKLVADQ 2016 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRR++D+DR EYGLDSLG LE+RT IE+ETGIR+ I T RALAQ LAD Sbjct: 2017 IGLILRRSVDSDRPLSEYGLDSLGTLEVRTRIENETGIRIGSTDI---TTVRALAQRLAD 2073 Query: 2097 TLAEEEGVAA 2106 TLA + G ++ Sbjct: 2074 TLAGDSGTSS 2083 >tr|A3Q182|A3Q182_MYCSJ Tax_Id=164757 SubName: Full=Acyl transferase domain protein;[Mycobacterium sp.] Length = 2085 Score = 2402 bits (6226), Expect = 0.0 Identities = 1237/2110 (58%), Positives = 1505/2110 (71%), Gaps = 32/2110 (1%) Query: 1 METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPG 60 ++ VTPIAVIGM CRLPGGI+SP++LWE+LLRGD+ VTEVP DRWD D++YDPEPGVPG Sbjct: 2 VDAPVTPIAVIGMACRLPGGIDSPERLWEALLRGDDFVTEVPLDRWDADEYYDPEPGVPG 61 Query: 61 RSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSS 120 RSVS+WG FLDDVAGFDAEFFGISEREAT+IDPQ RLLLET+WEA+E G+DPA+L S Sbjct: 62 RSVSKWGAFLDDVAGFDAEFFGISEREATAIDPQHRLLLETAWEAVEHAGIDPAALHESL 121 Query: 121 TAVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSG 180 T VF G+TH DY ++ A + PY TG N S+ASGRIS+ +GLHGPA T D+ACSS Sbjct: 122 TGVFIGMTHGDYQLVAADANAIEGPYGFTGNNYSLASGRISYAMGLHGPAYTVDSACSSS 181 Query: 181 LMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVR 240 L+AVH+ACRSLHDGESD+ALAGG +++LEP + SAQGMLS TGRC +F DADGFV Sbjct: 182 LLAVHMACRSLHDGESDMALAGGVSIMLEPRKMSSGSAQGMLSPTGRCHAFDVDADGFVS 241 Query: 241 SEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXX 300 E +++ KRL DA RDG+RI A++ G+A NQDG T + PS + Sbjct: 242 GEASVVLMFKRLADAQRDGDRILAVVKGSAANQDGHTVNIATPSRNAQVSVYRAALAAAG 301 Query: 301 XEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIK 360 +P T+G+VEAHGTGTP+GDPIEY LA VYG PCALGS K+N GH +++G +GL+K Sbjct: 302 MDPATVGMVEAHGTGTPVGDPIEYAGLAEVYGIDAPCALGSVKTNFGHGQSASGAIGLMK 361 Query: 361 AILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT 420 AILSL++ VP LH+ R+ D++ + T LFVPQE+TPWP G P+R AVSS+G+SGT Sbjct: 362 AILSLQHATVPQNLHYTRMPDEMARVSTNLFVPQEITPWPRG--EQPRRAAVSSYGLSGT 419 Query: 421 NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQ 480 NVH ++E+AP EA AP V T LF LS+TS LR TA +LA WV+ Sbjct: 420 NVHAVLEQAP-EAPAPVVEPTDKA--------MLFPLSATSAEELRRTAARLADWVDAQS 470 Query: 481 DSVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 D L DLAYTLAR R HRPVRT+V AA EL++ L EIADG+ Y+ V G+RGPVW Sbjct: 471 DGD-LRDLAYTLARRRGHRPVRTSVSAATREELIKALREIADGETPYEPAVAKGERGPVW 529 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA MG LLA EPVFAA + +LEP+IA ES FSVTEA++APE VTGID+VQP Sbjct: 530 VFSGQGSQWAGMGKGLLATEPVFAAAVAELEPLIARESGFSVTEAMSAPEKVTGIDRVQP 589 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 +VFAVQ+ALA TM+ +YGV PGAVIGHSM D A+VICRRS+LM R+ Sbjct: 590 TVFAVQIALAATMK-SYGVTPGAVIGHSMGESAAAVVAGGLSLEDGAKVICRRSRLMARI 648 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELPA+QV SEL ARGI DVV+SVVASPQSTV+GGA E++R+L+A+W+ R V Sbjct: 649 AGSGAMASVELPAQQVLSELAARGISDVVLSVVASPQSTVVGGAKESIRELVAEWDARGV 708 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 MAREVAVDVASHS QV M P++PYYSATL+DPR+ + YWVD Sbjct: 709 MAREVAVDVASHSPQVDPILDELTEVLEDIEPMEPELPYYSATLYDPRDPAEFDAYYWVD 768 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR+ V+F+AAVQAA+EDG+RVF EL+PHPLLTHAV+QT R+LDMS+AALA MRREQ P Sbjct: 769 NLRHAVRFSAAVQAALEDGFRVFGELAPHPLLTHAVDQTGRSLDMSLAALAAMRREQESP 828 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 GL +AD+H+AG A+DF+ ++P GRL+DAPLP WTH L + DGQEQ QG TV V Sbjct: 829 DGLLSFVADVHNAGGAVDFSVIFPDGRLVDAPLPTWTHVHLMLTRDGQEQ-TQGGSTVAV 887 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HVRL EEPERH+WQ DVGT A WL DHQVHNVAALPGAAYCEM Sbjct: 888 HPLLGAHVRLPEEPERHVWQVDVGTVAQPWLGDHQVHNVAALPGAAYCEMALAASRTVFG 947 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FE MLLL +TP+ ++A+V PGV +FVV+ +G ++R ATA LH + Sbjct: 948 DSAEVRDITFEAMLLLEDQTPVSSVATVKRPGVADFVVETYDEGAEVRRATAVLHGDDTA 1007 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 P AYD+ LL AHP G DL FAERG+ TVLAEVA Sbjct: 1008 EAPAAYDVDELLTAHPERREGADLHSWFAERGISYGQAFSGLVAAHTRDDGGNTVLAEVA 1067 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP SIR QQ +Y IHPALLDACFQ+VGA A L+LPLGVR L + RNA Sbjct: 1068 LPGSIRSQQGAYGIHPALLDACFQAVGAH-SALHADVTGTLMLPLGVRLLSAHASMRNAH 1126 Query: 1141 YCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ 1200 YCY +T + EAD++VLDE GAVLL V GL +G+G T G +R L+ERLLTI W+ Sbjct: 1127 YCYVTVTNVSAAAVEADIEVLDEDGAVLLTVEGLRLGSGATAGGHRERLLNERLLTIDWR 1186 Query: 1201 QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLI-QDDP 1259 + PE+ HV+ G WLLI T + A P+ A+ L+DAL T + W + Q D Sbjct: 1187 TQDRPEADHVDAGRWLLIAT-STDAQPE--AARLSDALSG---ADAHVTTMVWPVEQADH 1240 Query: 1260 VVSRERLGRQLRG--RDGVVILCGP-RAGAPDEQSLLAAREQVRHLVRIIRELAELEGEL 1316 + + +L GVV++ P R A Q +QVRHLVRI REL E+ GE Sbjct: 1241 AATAAHVIDRLTADHHSGVVVVTAPVRTDAAPAQGA----DQVRHLVRIARELPEVPGEP 1296 Query: 1317 PRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQL 1376 PRLFV+T AQ V + D ANLEQAGLRGL+RV++ EHP LR T VD+D TD +A QL Sbjct: 1297 PRLFVLTHNAQTVLADDVANLEQAGLRGLMRVLAMEHPALRPTQVDLDPATDAAALAAQL 1356 Query: 1377 LSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVA 1436 LSGSEEDETAWR GD++VARL SPL E+RRT V+N E DG+R+ +R PGDL+SLEL A Sbjct: 1357 LSGSEEDETAWRGGDFHVARLALSPLRPEERRTTVVNHETDGMRLQIRTPGDLESLELAA 1416 Query: 1437 SDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXH 1496 DRVPPGPG++EV+V+ S++NFADVL+A+GR+P + R P+LG DF H Sbjct: 1417 FDRVPPGPGEIEVSVTASNLNFADVLVAYGRYPSFEGRLPKLGADFAGVVTGVGPGVTEH 1476 Query: 1497 QIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKV 1556 Q+GDRV G S G W TF+TCDANLAV LP+G+ +++ WYGL+DLA I Sbjct: 1477 QVGDRVAGISANGAWATFVTCDANLAVKLPAGVPEDRAAAVPSAHATAWYGLHDLARIGA 1536 Query: 1557 GDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ 1616 DKVLIHSATGGVGQAA++IA+A GAEI+ATAG+P +R +L D+GIEHVYDSRS FA++ Sbjct: 1537 RDKVLIHSATGGVGQAAVAIAKAAGAEIYATAGSPERRKILRDMGIEHVYDSRSTAFADE 1596 Query: 1617 IRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTF 1676 IR DT GYGVDIVLNSL GAAQRAGLELL+FGGRFVEIGK D+YG++++GLFPFRR L F Sbjct: 1597 IREDTAGYGVDIVLNSLPGAAQRAGLELLSFGGRFVEIGKRDIYGDSKMGLFPFRRNLAF 1656 Query: 1677 YYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGK 1736 Y +DLAL+++T PD +R LL TV+ ADGVL PE THYPL D A AIR M A HTGK Sbjct: 1657 YAVDLALLTLTNPDILRRLLETVYQQIADGVLPLPETTHYPLADGATAIRVMGAAGHTGK 1716 Query: 1737 LVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARS 1796 LVLD+P TG + VPPE A V+R DG+Y++T F A K+A AGCGRIVL RS Sbjct: 1717 LVLDVPHTGQSTAVVPPENAEVFRGDGAYVVTGGMGGLGLFLAEKMAAAGCGRIVLNGRS 1776 Query: 1797 QPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDA 1856 PNP A I+R+ A G ++ V G+IA+P TADR++ AATATGLP+RGVLH+AAVVEDA Sbjct: 1777 APNPAATAAIDRIRAGGTEVEVSLGDIADPATADRVIAAATATGLPVRGVLHAAAVVEDA 1836 Query: 1857 TLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSW 1916 TL NITDELIDRDW+PKV G+WNLH AT+ QPLDWFC FSS AA++GSPGQGAYAAANSW Sbjct: 1837 TLPNITDELIDRDWAPKVQGAWNLHAATLDQPLDWFCSFSSAAAMVGSPGQGAYAAANSW 1896 Query: 1917 VDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYS 1976 +D F HWRRAQGLP SAIAWGAW E+G+ +AE + I PD+GA AF+ L+R++R Y Sbjct: 1897 LDAFTHWRRAQGLPASAIAWGAWAEIGKGQGMAEDTAMAILPDDGADAFDALLRHNRGYC 1956 Query: 1977 GYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQ 2036 GY P+ GAPWL + S +AE F+S GQG G S F EL LPQ+EW GRLR+L+ +Q Sbjct: 1957 GYAPVAGAPWLTAFAQTSKFAEAFASIGQGGTGTSAFLTELFELPQEEWPGRLRKLVADQ 2016 Query: 2037 ASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLAD 2096 +ILRR++D+DR EYGLDSLG LE+RT IE+ETGIR+ I T RALAQ LAD Sbjct: 2017 IGLILRRSVDSDRPLSEYGLDSLGTLEVRTRIENETGIRIGSTDI---TTVRALAQRLAD 2073 Query: 2097 TLAEEEGVAA 2106 TLA + G ++ Sbjct: 2074 TLAGDSGTSS 2083 >tr|C1AMH5|C1AMH5_MYCBT Tax_Id=561275 (pks3)SubName: Full=Putative polyketide beta-ketoacyl synthase;[Mycobacterium bovis] Length = 2085 Score = 2320 bits (6012), Expect = 0.0 Identities = 1207/2101 (57%), Positives = 1459/2101 (69%), Gaps = 32/2101 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 + T +AVIGM CRLPGGI+SP +LWE+LLRGD+LV E+P DRWD + +YDPEPGVPGRSV Sbjct: 5 TATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSV 64 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREAT+IDPQ RLLLE SWEAIE G+DPA+LA S T V Sbjct: 65 SRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGV 124 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGL A Sbjct: 125 FVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTA 184 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH ACRSL DGESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 185 VHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEG 244 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKRLPDA+RDG+R+ A++ GTA NQDG T + PS E Sbjct: 245 CVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEA 304 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G+VEAHGTGTP+GDP+EY SLA VYG PCAL S K+N GH +++G +GL+K IL Sbjct: 305 STVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTIL 364 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +LR+G+VP LHF RL D L EI+T LFVPQ T WP P+R AVSS+GMSGTNVH Sbjct: 365 ALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNVH 423 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS- 482 I+E+AP A PE +P G G LF +S+TS L TA +LA WV+++ ++ Sbjct: 424 AILEQAPVSEPAASGPELTPEAG----GLALFPVSATSAEQLHVTAARLADWVDQNGNAG 479 Query: 483 --VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 V + DL YTL+ RAHRPVRT V A+ EL L ++A Y VGH DRGPVW Sbjct: 480 SRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVW 539 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LL EPVFAAT+ +EPVIA ES FSVTEA++AP+TV+GID+VQP Sbjct: 540 VFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQP 599 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FAVQVALA ++ +YGVRPGA+IGHS+ D RVICRRS+LM+R+ Sbjct: 600 TIFAVQVALAAALK-SYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRI 658 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RGI DVV+SVVASP STV+GGAT+++RDL+A WEQ+DV Sbjct: 659 AGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDV 718 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +AREVAVDVASH+ QV P++PYYSATL+DPRE P G YWV+ Sbjct: 719 LAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVE 778 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DGYRVF EL+PHPLLT+AVEQ A +LDM +A LA MRR + +P Sbjct: 779 NLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLP 838 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+H+AGA +DF+ YP GRL+DAPLP WTH L + + + GA V Sbjct: 839 FGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQA-V 897 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH+WQ VGT A WL DH++HNVAA PGAAYCEM Sbjct: 898 HPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLG 957 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQ LLL +T + + A++ APG++ F V+++Q+GE R A+A LHA E+ Sbjct: 958 ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEM 1017 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PP YD AL AH +S++G +LR+ F G+Q TVLAEVA Sbjct: 1018 PQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGAVTTVLAEVA 1077 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP +IR QQS+Y HPALLDACFQSV + K + GL+LP+GVR LR Y TR+A Sbjct: 1078 LPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKA-TVGGLMLPVGVRRLRNYHSTRSAH 1136 Query: 1141 YCYTRLTKIEPRGG-EADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 YC R+T G EADLDV D+ G VLL V GL + G +E +R ERLLTI W Sbjct: 1137 YCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEW 1196 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 ++ LPE ++ GSWLL+ A D + L DAL + G Q T + S D Sbjct: 1197 ERGELPEVPQIDAGSWLLLSASEA----DPLTAQLADALNAVGAQSTSVASAS-----DV 1247 Query: 1260 VVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRL 1319 R LG +L G VV++ GP G + R+ V LV I RELAEL GE PRL Sbjct: 1248 AQLRSLLGGRLTG---VVVVTGPPTGGLTQ----CGRDYVSQLVGIARELAELPGEPPRL 1300 Query: 1320 FVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVD-EHTDVERVAQQLLS 1378 FVVTR A V D ANLEQAGLRGL+RVI SEHP L T +DVD + T VA QL S Sbjct: 1301 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQS 1360 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GS+EDETAWRNG WY ARL P PL +RRT V+ DG+R+ +R PGDL+SLE V D Sbjct: 1361 GSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFD 1420 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RVPPGPG++EVAV+ SS+NFADVL+AFGR+P + QLG+DF H+I Sbjct: 1421 RVPPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRI 1480 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG S GCW TF+ CDA LAVTLP L WY L+DLA I D Sbjct: 1481 GDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD 1540 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA G EIFATAG+ +R +LHD+G+EHVYDSRS EFAEQIR Sbjct: 1541 KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIR 1600 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+TRLGLFPFRR L+ Y Sbjct: 1601 GDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA 1660 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DLAL++ + P VR LL TV+ T +G L P+ THYP+ DAA AIR + A HTGK+V Sbjct: 1661 VDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVV 1720 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+PRTG VPPEQ R DG+Y++T F A +LA AGCGRIVL +RS P Sbjct: 1721 LDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTP 1780 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 +P A + IERL AAGADI VECG+IA+ TA R+V ATA+GLP+RGVLH+AAVVEDATL Sbjct: 1781 SPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATL 1840 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 N+TDELIDR W+PKV+G+WN+H AT QPL+WFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1841 ANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLD 1900 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 FAHWRRAQGLP ++IAWGAW E+GRAT LAEG I P EGA AF+ L+RY R YSGY Sbjct: 1901 AFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY 1960 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PI+G PWL +RS +AE F + GQ KF EL +LP++EW +RRL+ +Q S Sbjct: 1961 APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQIS 2020 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 ++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P I T R LA+++ D L Sbjct: 2021 LLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKI---TTVRGLAEHVCDEL 2077 Query: 2099 A 2099 A Sbjct: 2078 A 2078 >tr|A1KHX1|A1KHX1_MYCBP Tax_Id=410289 (pks3)SubName: Full=Probable polyketide beta-ketoacyl synthase pks3; EC=2.3.1.-;[Mycobacterium bovis] Length = 2085 Score = 2320 bits (6012), Expect = 0.0 Identities = 1207/2101 (57%), Positives = 1459/2101 (69%), Gaps = 32/2101 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 + T +AVIGM CRLPGGI+SP +LWE+LLRGD+LV E+P DRWD + +YDPEPGVPGRSV Sbjct: 5 TATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSV 64 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREAT+IDPQ RLLLE SWEAIE G+DPA+LA S T V Sbjct: 65 SRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGV 124 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGL A Sbjct: 125 FVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTA 184 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH ACRSL DGESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 185 VHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEG 244 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKRLPDA+RDG+R+ A++ GTA NQDG T + PS E Sbjct: 245 CVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEA 304 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G+VEAHGTGTP+GDP+EY SLA VYG PCAL S K+N GH +++G +GL+K IL Sbjct: 305 STVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTIL 364 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +LR+G+VP LHF RL D L EI+T LFVPQ T WP P+R AVSS+GMSGTNVH Sbjct: 365 ALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNVH 423 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS- 482 I+E+AP A PE +P G G LF +S+TS L TA +LA WV+++ ++ Sbjct: 424 AILEQAPVSEPAASGPELTPEAG----GLALFPVSATSAEQLHVTAARLADWVDQNGNAG 479 Query: 483 --VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 V + DL YTL+ RAHRPVRT V A+ EL L ++A Y VGH DRGPVW Sbjct: 480 SRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVW 539 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LL EPVFAAT+ +EPVIA ES FSVTEA++AP+TV+GID+VQP Sbjct: 540 VFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQP 599 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FAVQVALA ++ +YGVRPGA+IGHS+ D RVICRRS+LM+R+ Sbjct: 600 TIFAVQVALAAALK-SYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRI 658 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RGI DVV+SVVASP STV+GGAT+++RDL+A WEQ+DV Sbjct: 659 AGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDV 718 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +AREVAVDVASH+ QV P++PYYSATL+DPRE P G YWV+ Sbjct: 719 LAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVE 778 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DGYRVF EL+PHPLLT+AVEQ A +LDM +A LA MRR + +P Sbjct: 779 NLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLP 838 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+H+AGA +DF+ YP GRL+DAPLP WTH L + + + GA V Sbjct: 839 FGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQA-V 897 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH+WQ VGT A WL DH++HNVAA PGAAYCEM Sbjct: 898 HPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLG 957 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQ LLL +T + + A++ APG++ F V+++Q+GE R A+A LHA E+ Sbjct: 958 ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEM 1017 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PP YD AL AH +S++G +LR+ F G+Q TVLAEVA Sbjct: 1018 PQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGAVTTVLAEVA 1077 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP +IR QQS+Y HPALLDACFQSV + K + GL+LP+GVR LR Y TR+A Sbjct: 1078 LPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKA-TVGGLMLPVGVRRLRNYHSTRSAH 1136 Query: 1141 YCYTRLTKIEPRGG-EADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 YC R+T G EADLDV D+ G VLL V GL + G +E +R ERLLTI W Sbjct: 1137 YCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEW 1196 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 ++ LPE ++ GSWLL+ A D + L DAL + G Q T + S D Sbjct: 1197 ERGELPEVPQIDAGSWLLLSASEA----DPLTAQLADALNAVGAQSTSVASAS-----DV 1247 Query: 1260 VVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRL 1319 R LG +L G VV++ GP G + R+ V LV I RELAEL GE PRL Sbjct: 1248 AQLRSLLGGRLTG---VVVVTGPPTGGLTQ----CGRDYVSQLVGIARELAELPGEPPRL 1300 Query: 1320 FVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVD-EHTDVERVAQQLLS 1378 FVVTR A V D ANLEQAGLRGL+RVI SEHP L T +DVD + T VA QL S Sbjct: 1301 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQS 1360 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GS+EDETAWRNG WY ARL P PL +RRT V+ DG+R+ +R PGDL+SLE V D Sbjct: 1361 GSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFD 1420 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RVPPGPG++EVAV+ SS+NFADVL+AFGR+P + QLG+DF H+I Sbjct: 1421 RVPPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRI 1480 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG S GCW TF+ CDA LAVTLP L WY L+DLA I D Sbjct: 1481 GDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD 1540 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA G EIFATAG+ +R +LHD+G+EHVYDSRS EFAEQIR Sbjct: 1541 KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIR 1600 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+TRLGLFPFRR L+ Y Sbjct: 1601 GDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA 1660 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DLAL++ + P VR LL TV+ T +G L P+ THYP+ DAA AIR + A HTGK+V Sbjct: 1661 VDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVV 1720 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+PRTG VPPEQ R DG+Y++T F A +LA AGCGRIVL +RS P Sbjct: 1721 LDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTP 1780 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 +P A + IERL AAGADI VECG+IA+ TA R+V ATA+GLP+RGVLH+AAVVEDATL Sbjct: 1781 SPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATL 1840 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 N+TDELIDR W+PKV+G+WN+H AT QPL+WFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1841 ANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLD 1900 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 FAHWRRAQGLP ++IAWGAW E+GRAT LAEG I P EGA AF+ L+RY R YSGY Sbjct: 1901 AFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY 1960 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PI+G PWL +RS +AE F + GQ KF EL +LP++EW +RRL+ +Q S Sbjct: 1961 APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQIS 2020 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 ++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P I T R LA+++ D L Sbjct: 2021 LLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKI---TTVRGLAEHVCDEL 2077 Query: 2099 A 2099 A Sbjct: 2078 A 2078 >tr|Q7U0G2|Q7U0G2_MYCBO Tax_Id=1765 (pks3)SubName: Full=PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS3; EC=2.3.1.-;[Mycobacterium bovis] Length = 2085 Score = 2317 bits (6004), Expect = 0.0 Identities = 1206/2101 (57%), Positives = 1458/2101 (69%), Gaps = 32/2101 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 + T +AVIGM CRLPGGI+SP +LWE+LLRGD+LV E+P DRWD + +YDPEPGVPGRSV Sbjct: 5 TATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSV 64 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREAT+IDPQ RLLLE SWEAIE G+DPA+LA S T V Sbjct: 65 SRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGV 124 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGL A Sbjct: 125 FVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTA 184 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH ACRSL DGESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 185 VHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEG 244 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKRLPDA+RDG+R+ A++ GTA NQDG T + PS E Sbjct: 245 CVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEA 304 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G+VEAHGTGTP+GDP+EY SLA VYG PCAL S K+N GH +++G +GL+K IL Sbjct: 305 STVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTIL 364 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +LR+G+VP LHF RL D L EI+T LFVPQ T WP P+R AVSS+GMSGTNVH Sbjct: 365 ALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNVH 423 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS- 482 I+E+AP A PE +P G G LF +S+TS L TA +LA WV+++ ++ Sbjct: 424 AILEQAPVSEPAASGPELTPEAG----GLALFPVSATSAEQLHVTAARLADWVDQNGNAG 479 Query: 483 --VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 V + DL YTL+ RAHRPVRT V A+ EL L ++A Y VGH DRGPVW Sbjct: 480 SRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVW 539 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LL EPVFAAT+ +EPVIA ES FSVTEA++AP+TV+GID+VQP Sbjct: 540 VFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQP 599 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FAVQVALA ++ +YGVRPGA+IGHS+ D RVICRRS+LM+R+ Sbjct: 600 TIFAVQVALAAALK-SYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRI 658 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RGI DVV+SVVASP STV+GGAT+++RDL+A WEQ+DV Sbjct: 659 AGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDV 718 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +AREVAVDVASH+ QV P++PYYSATL+DPRE P G YWV+ Sbjct: 719 LAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVE 778 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DGYRVF EL+PHPLLT+AVEQ A +LDM +A LA MRR + +P Sbjct: 779 NLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLP 838 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+H+AGA +DF+ YP GRL+DAPLP WTH L + + + GA V Sbjct: 839 FGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQA-V 897 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH+WQ VGT A WL DH++HNVAA PGAAYCEM Sbjct: 898 HPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLG 957 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQ LLL +T + + A++ APG++ F V+++Q+GE R A+A LHA E+ Sbjct: 958 ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEM 1017 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PP YD AL AH +S++G +LR+ F G+Q TVLAEVA Sbjct: 1018 PQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGAVTTVLAEVA 1077 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP +IR QQS+Y HPALLDACFQSV + K + GL+LP+GVR LR Y TR+A Sbjct: 1078 LPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKA-TVGGLMLPVGVRRLRNYHSTRSAH 1136 Query: 1141 YCYTRLTKIEPRGG-EADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 YC R+T G EADLDV D+ G VLL V GL + G +E +R ERLLTI W Sbjct: 1137 YCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEW 1196 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 ++ LPE ++ GSWLL+ A D + L DAL + G Q T + S D Sbjct: 1197 ERGELPEVPQIDAGSWLLLSASEA----DPLTAQLADALNAVGAQSTSVASAS-----DV 1247 Query: 1260 VVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRL 1319 R LG +L G VV++ GP G + R+ V LV I RELAEL GE PRL Sbjct: 1248 AQLRSLLGGRLTG---VVVVTGPPTGGLTQ----CGRDYVSQLVGIARELAELPGEPPRL 1300 Query: 1320 FVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVD-EHTDVERVAQQLLS 1378 FVVTR A V D ANLEQAGLRGL+RVI SEHP L T +DVD + T VA QL S Sbjct: 1301 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQS 1360 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GS+EDETAWRNG WY ARL P PL +RRT V+ DG+R+ +R PGDL+SLE V D Sbjct: 1361 GSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFD 1420 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RV PGPG++EVAV+ SS+NFADVL+AFGR+P + QLG+DF H+I Sbjct: 1421 RVAPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRI 1480 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG S GCW TF+ CDA LAVTLP L WY L+DLA I D Sbjct: 1481 GDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD 1540 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA G EIFATAG+ +R +LHD+G+EHVYDSRS EFAEQIR Sbjct: 1541 KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIR 1600 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+TRLGLFPFRR L+ Y Sbjct: 1601 GDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA 1660 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DLAL++ + P VR LL TV+ T +G L P+ THYP+ DAA AIR + A HTGK+V Sbjct: 1661 VDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVV 1720 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+PRTG VPPEQ R DG+Y++T F A +LA AGCGRIVL +RS P Sbjct: 1721 LDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTP 1780 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 +P A + IERL AAGADI VECG+IA+ TA R+V ATA+GLP+RGVLH+AAVVEDATL Sbjct: 1781 SPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATL 1840 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 N+TDELIDR W+PKV+G+WN+H AT QPL+WFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1841 ANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLD 1900 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 FAHWRRAQGLP ++IAWGAW E+GRAT LAEG I P EGA AF+ L+RY R YSGY Sbjct: 1901 AFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY 1960 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PI+G PWL +RS +AE F + GQ KF EL +LP++EW +RRL+ +Q S Sbjct: 1961 APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQIS 2020 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 ++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P I T R LA+++ D L Sbjct: 2021 LLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKI---TTVRGLAEHVCDEL 2077 Query: 2099 A 2099 A Sbjct: 2078 A 2078 >tr|C6DUX7|C6DUX7_MYCTK Tax_Id=478434 SubName: Full=Polyketide beta-ketoacyl synthase;[Mycobacterium tuberculosis] Length = 2101 Score = 2317 bits (6004), Expect = 0.0 Identities = 1206/2101 (57%), Positives = 1458/2101 (69%), Gaps = 32/2101 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 + T +AVIGM CRLPGGI+SP +LWE+LLRGD+LV E+P DRWD + +YDPEPGVPGRSV Sbjct: 21 TATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSV 80 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREAT+IDPQ RLLLE SWEAIE G+DPA+LA S T V Sbjct: 81 SRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGV 140 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGL A Sbjct: 141 FVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTA 200 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH ACRSL DGESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 201 VHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEG 260 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKRLPDA+RDG+R+ A++ GTA NQDG T + PS E Sbjct: 261 CVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEA 320 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G+VEAHGTGTP+GDP+EY SLA VYG PCAL S K+N GH +++G +GL+K IL Sbjct: 321 STVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTIL 380 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +LR+G+VP LHF RL D L EI+T LFVPQ T WP P+R AVSS+GMSGTNVH Sbjct: 381 ALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNVH 439 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS- 482 I+E+AP A PE +P G G LF +S+TS L TA +LA WV+++ ++ Sbjct: 440 AILEQAPVSEPAASGPELTPEAG----GLALFPVSATSAEQLHVTAARLADWVDQNGNAG 495 Query: 483 --VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 V + DL YTL+ RAHRPVRT V A+ EL L ++A Y VGH DRGPVW Sbjct: 496 SRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVW 555 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LL EPVFAAT+ +EPVIA ES FSVTEA++AP+TV+GID+VQP Sbjct: 556 VFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQP 615 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FAVQVALA ++ +YGVRPGA+IGHS+ D RVICRRS+LM+R+ Sbjct: 616 TIFAVQVALAAALK-SYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRI 674 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RGI DVV+SVVASP STV+GGAT+++RDL+A WEQ+DV Sbjct: 675 AGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDV 734 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +AREVAVDVASH+ QV P++PYYSATL+DPRE P G YWV+ Sbjct: 735 LAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVE 794 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DGYRVF EL+PHPLLT+AVEQ A +LDM +A LA MRR + +P Sbjct: 795 NLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLP 854 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+H+AGA +DF+ YP GRL+DAPLP WTH L + + + GA V Sbjct: 855 FGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQA-V 913 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH+WQ VGT A WL DH++HNVAA PGAAYCEM Sbjct: 914 HPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLG 973 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQ LLL +T + + A++ APG++ F V+++Q+GE R A+A LHA E+ Sbjct: 974 ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEM 1033 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PP YD AL AH +S++G +LR+ F G+Q TVLAEVA Sbjct: 1034 PQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGDVTTVLAEVA 1093 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP +IR QQS+Y HPALLDACFQSV + K + GL+LP+GVR LR Y TR+A Sbjct: 1094 LPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKA-TVGGLMLPVGVRRLRNYHSTRSAH 1152 Query: 1141 YCYTRLTKIEPRGG-EADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 YC R+T G EADLDV D+ G VLL V GL + G +E +R ERLLTI W Sbjct: 1153 YCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 ++ LPE ++ GSWLL+ A D + L DAL + G Q T + S D Sbjct: 1213 ERGELPEVPQIDAGSWLLLSASEA----DPLTAQLADALNAVGAQSTSVASAS-----DV 1263 Query: 1260 VVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRL 1319 R LG +L G VV++ GP G + R+ V LV I RELAEL GE PRL Sbjct: 1264 AQLRSLLGGRLTG---VVVVTGPPTGGLTQ----CGRDYVSQLVGIARELAELPGEPPRL 1316 Query: 1320 FVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVD-EHTDVERVAQQLLS 1378 FVVTR A V D ANLEQAGLRGL+RVI SEHP L T +DVD + T VA QL S Sbjct: 1317 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQS 1376 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GS+EDETAWRNG WY ARL P PL +RRT V+ DG+R+ +R PGDL+SLE V D Sbjct: 1377 GSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFD 1436 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RV PGPG++EVAV+ SS+NFADVL+AFGR+P + QLG+DF H+I Sbjct: 1437 RVAPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRI 1496 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG S GCW TF+ CDA LAVTLP L WY L+DLA I D Sbjct: 1497 GDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD 1556 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA G EIFATAG+ +R +LHD+G+EHVYDSRS EFAEQIR Sbjct: 1557 KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIR 1616 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+TRLGLFPFRR L+ Y Sbjct: 1617 GDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA 1676 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DLAL++ + P VR LL TV+ T +G L P+ THYP+ DAA AIR + A HTGK+V Sbjct: 1677 VDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVV 1736 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+PRTG VPPEQ R DG+Y++T F A +LA AGCGRIVL +RS P Sbjct: 1737 LDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTP 1796 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 +P A + IERL AAGADI VECG+IA+ TA R+V ATA+GLP+RGVLH+AAVVEDATL Sbjct: 1797 SPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATL 1856 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 N+TDELIDR W+PKV+G+WN+H AT QPL+WFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1857 ANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLD 1916 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 FAHWRRAQGLP ++IAWGAW E+GRAT LAEG I P EGA AF+ L+RY R YSGY Sbjct: 1917 AFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY 1976 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PI+G PWL +RS +AE F + GQ KF EL +LP++EW +RRL+ +Q S Sbjct: 1977 APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQIS 2036 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 ++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P I T R LA+++ D L Sbjct: 2037 LLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKI---TTVRGLAEHVCDEL 2093 Query: 2099 A 2099 A Sbjct: 2094 A 2094 >tr|A5U1M9|A5U1M9_MYCTA Tax_Id=419947 (pks3)SubName: Full=Polyketide beta-ketoacyl synthase Pks3;[Mycobacterium tuberculosis] Length = 2085 Score = 2317 bits (6004), Expect = 0.0 Identities = 1206/2101 (57%), Positives = 1458/2101 (69%), Gaps = 32/2101 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 + T +AVIGM CRLPGGI+SP +LWE+LLRGD+LV E+P DRWD + +YDPEPGVPGRSV Sbjct: 5 TATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSV 64 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREAT+IDPQ RLLLE SWEAIE G+DPA+LA S T V Sbjct: 65 SRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGV 124 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGL A Sbjct: 125 FVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTA 184 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH ACRSL DGESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 185 VHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEG 244 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKRLPDA+RDG+R+ A++ GTA NQDG T + PS E Sbjct: 245 CVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEA 304 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G+VEAHGTGTP+GDP+EY SLA VYG PCAL S K+N GH +++G +GL+K IL Sbjct: 305 STVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTIL 364 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +LR+G+VP LHF RL D L EI+T LFVPQ T WP P+R AVSS+GMSGTNVH Sbjct: 365 ALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNVH 423 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS- 482 I+E+AP A PE +P G G LF +S+TS L TA +LA WV+++ ++ Sbjct: 424 AILEQAPVSEPAASGPELTPEAG----GLALFPVSATSAEQLHVTAARLADWVDQNGNAG 479 Query: 483 --VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 V + DL YTL+ RAHRPVRT V A+ EL L ++A Y VGH DRGPVW Sbjct: 480 SRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVW 539 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LL EPVFAAT+ +EPVIA ES FSVTEA++AP+TV+GID+VQP Sbjct: 540 VFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQP 599 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FAVQVALA ++ +YGVRPGA+IGHS+ D RVICRRS+LM+R+ Sbjct: 600 TIFAVQVALAAALK-SYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRI 658 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RGI DVV+SVVASP STV+GGAT+++RDL+A WEQ+DV Sbjct: 659 AGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDV 718 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +AREVAVDVASH+ QV P++PYYSATL+DPRE P G YWV+ Sbjct: 719 LAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVE 778 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DGYRVF EL+PHPLLT+AVEQ A +LDM +A LA MRR + +P Sbjct: 779 NLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLP 838 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+H+AGA +DF+ YP GRL+DAPLP WTH L + + + GA V Sbjct: 839 FGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQA-V 897 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH+WQ VGT A WL DH++HNVAA PGAAYCEM Sbjct: 898 HPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLG 957 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQ LLL +T + + A++ APG++ F V+++Q+GE R A+A LHA E+ Sbjct: 958 ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEM 1017 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PP YD AL AH +S++G +LR+ F G+Q TVLAEVA Sbjct: 1018 PQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGDVTTVLAEVA 1077 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP +IR QQS+Y HPALLDACFQSV + K + GL+LP+GVR LR Y TR+A Sbjct: 1078 LPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKA-TVGGLMLPVGVRRLRNYHSTRSAH 1136 Query: 1141 YCYTRLTKIEPRGG-EADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 YC R+T G EADLDV D+ G VLL V GL + G +E +R ERLLTI W Sbjct: 1137 YCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEW 1196 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 ++ LPE ++ GSWLL+ A D + L DAL + G Q T + S D Sbjct: 1197 ERGELPEVPQIDAGSWLLLSASEA----DPLTAQLADALNAVGAQSTSVASAS-----DV 1247 Query: 1260 VVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRL 1319 R LG +L G VV++ GP G + R+ V LV I RELAEL GE PRL Sbjct: 1248 AQLRSLLGGRLTG---VVVVTGPPTGGLTQ----CGRDYVSQLVGIARELAELPGEPPRL 1300 Query: 1320 FVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVD-EHTDVERVAQQLLS 1378 FVVTR A V D ANLEQAGLRGL+RVI SEHP L T +DVD + T VA QL S Sbjct: 1301 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQS 1360 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GS+EDETAWRNG WY ARL P PL +RRT V+ DG+R+ +R PGDL+SLE V D Sbjct: 1361 GSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFD 1420 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RV PGPG++EVAV+ SS+NFADVL+AFGR+P + QLG+DF H+I Sbjct: 1421 RVAPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRI 1480 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG S GCW TF+ CDA LAVTLP L WY L+DLA I D Sbjct: 1481 GDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD 1540 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA G EIFATAG+ +R +LHD+G+EHVYDSRS EFAEQIR Sbjct: 1541 KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIR 1600 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+TRLGLFPFRR L+ Y Sbjct: 1601 GDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA 1660 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DLAL++ + P VR LL TV+ T +G L P+ THYP+ DAA AIR + A HTGK+V Sbjct: 1661 VDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVV 1720 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+PRTG VPPEQ R DG+Y++T F A +LA AGCGRIVL +RS P Sbjct: 1721 LDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTP 1780 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 +P A + IERL AAGADI VECG+IA+ TA R+V ATA+GLP+RGVLH+AAVVEDATL Sbjct: 1781 SPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATL 1840 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 N+TDELIDR W+PKV+G+WN+H AT QPL+WFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1841 ANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLD 1900 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 FAHWRRAQGLP ++IAWGAW E+GRAT LAEG I P EGA AF+ L+RY R YSGY Sbjct: 1901 AFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY 1960 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PI+G PWL +RS +AE F + GQ KF EL +LP++EW +RRL+ +Q S Sbjct: 1961 APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQIS 2020 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 ++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P I T R LA+++ D L Sbjct: 2021 LLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKI---TTVRGLAEHVCDEL 2077 Query: 2099 A 2099 A Sbjct: 2078 A 2078 >tr|Q8VK52|Q8VK52_MYCTU Tax_Id=1773 (mas-1)SubName: Full=Mycocerosic acid synthase; EC=2.7.1.-;[Mycobacterium tuberculosis] Length = 2101 Score = 2317 bits (6004), Expect = 0.0 Identities = 1206/2101 (57%), Positives = 1458/2101 (69%), Gaps = 32/2101 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 + T +AVIGM CRLPGGI+SP +LWE+LLRGD+LV E+P DRWD + +YDPEPGVPGRSV Sbjct: 21 TATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSV 80 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREAT+IDPQ RLLLE SWEAIE G+DPA+LA S T V Sbjct: 81 SRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGV 140 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGL A Sbjct: 141 FVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTA 200 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH ACRSL DGESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 201 VHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEG 260 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKRLPDA+RDG+R+ A++ GTA NQDG T + PS E Sbjct: 261 CVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEA 320 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G+VEAHGTGTP+GDP+EY SLA VYG PCAL S K+N GH +++G +GL+K IL Sbjct: 321 STVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTIL 380 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +LR+G+VP LHF RL D L EI+T LFVPQ T WP P+R AVSS+GMSGTNVH Sbjct: 381 ALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNVH 439 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS- 482 I+E+AP A PE +P G G LF +S+TS L TA +LA WV+++ ++ Sbjct: 440 AILEQAPVSEPAASGPELTPEAG----GLALFPVSATSAEQLHVTAARLADWVDQNGNAG 495 Query: 483 --VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 V + DL YTL+ RAHRPVRT V A+ EL L ++A Y VGH DRGPVW Sbjct: 496 SRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVW 555 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LL EPVFAAT+ +EPVIA ES FSVTEA++AP+TV+GID+VQP Sbjct: 556 VFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQP 615 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FAVQVALA ++ +YGVRPGA+IGHS+ D RVICRRS+LM+R+ Sbjct: 616 TIFAVQVALAAALK-SYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRI 674 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RGI DVV+SVVASP STV+GGAT+++RDL+A WEQ+DV Sbjct: 675 AGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDV 734 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +AREVAVDVASH+ QV P++PYYSATL+DPRE P G YWV+ Sbjct: 735 LAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVE 794 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DGYRVF EL+PHPLLT+AVEQ A +LDM +A LA MRR + +P Sbjct: 795 NLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLP 854 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+H+AGA +DF+ YP GRL+DAPLP WTH L + + + GA V Sbjct: 855 FGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQA-V 913 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH+WQ VGT A WL DH++HNVAA PGAAYCEM Sbjct: 914 HPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLG 973 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQ LLL +T + + A++ APG++ F V+++Q+GE R A+A LHA E+ Sbjct: 974 ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEM 1033 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PP YD AL AH +S++G +LR+ F G+Q TVLAEVA Sbjct: 1034 PQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGDVTTVLAEVA 1093 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP +IR QQS+Y HPALLDACFQSV + K + GL+LP+GVR LR Y TR+A Sbjct: 1094 LPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKA-TVGGLMLPVGVRRLRNYHSTRSAH 1152 Query: 1141 YCYTRLTKIEPRGG-EADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 YC R+T G EADLDV D+ G VLL V GL + G +E +R ERLLTI W Sbjct: 1153 YCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 ++ LPE ++ GSWLL+ A D + L DAL + G Q T + S D Sbjct: 1213 ERGELPEVPQIDAGSWLLLSASEA----DPLTAQLADALNAVGAQSTSVASAS-----DV 1263 Query: 1260 VVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRL 1319 R LG +L G VV++ GP G + R+ V LV I RELAEL GE PRL Sbjct: 1264 AQLRSLLGGRLTG---VVVVTGPPTGGLTQ----CGRDYVSQLVGIARELAELPGEPPRL 1316 Query: 1320 FVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVD-EHTDVERVAQQLLS 1378 FVVTR A V D ANLEQAGLRGL+RVI SEHP L T +DVD + T VA QL S Sbjct: 1317 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQS 1376 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GS+EDETAWRNG WY ARL P PL +RRT V+ DG+R+ +R PGDL+SLE V D Sbjct: 1377 GSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFD 1436 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RV PGPG++EVAV+ SS+NFADVL+AFGR+P + QLG+DF H+I Sbjct: 1437 RVAPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRI 1496 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG S GCW TF+ CDA LAVTLP L WY L+DLA I D Sbjct: 1497 GDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD 1556 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA G EIFATAG+ +R +LHD+G+EHVYDSRS EFAEQIR Sbjct: 1557 KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIR 1616 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+TRLGLFPFRR L+ Y Sbjct: 1617 GDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA 1676 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DLAL++ + P VR LL TV+ T +G L P+ THYP+ DAA AIR + A HTGK+V Sbjct: 1677 VDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVV 1736 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+PRTG VPPEQ R DG+Y++T F A +LA AGCGRIVL +RS P Sbjct: 1737 LDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTP 1796 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 +P A + IERL AAGADI VECG+IA+ TA R+V ATA+GLP+RGVLH+AAVVEDATL Sbjct: 1797 SPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATL 1856 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 N+TDELIDR W+PKV+G+WN+H AT QPL+WFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1857 ANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLD 1916 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 FAHWRRAQGLP ++IAWGAW E+GRAT LAEG I P EGA AF+ L+RY R YSGY Sbjct: 1917 AFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY 1976 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PI+G PWL +RS +AE F + GQ KF EL +LP++EW +RRL+ +Q S Sbjct: 1977 APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQIS 2036 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 ++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P I T R LA+++ D L Sbjct: 2037 LLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKI---TTVRGLAEHVCDEL 2093 Query: 2099 A 2099 A Sbjct: 2094 A 2094 >tr|A5WLK9|A5WLK9_MYCTF Tax_Id=336982 SubName: Full=Polyketide beta-ketoacyl synthase pks4;[Mycobacterium tuberculosis] Length = 2101 Score = 2317 bits (6004), Expect = 0.0 Identities = 1206/2101 (57%), Positives = 1458/2101 (69%), Gaps = 32/2101 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 + T +AVIGM CRLPGGI+SP +LWE+LLRGD+LV E+P DRWD + +YDPEPGVPGRSV Sbjct: 21 TATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSV 80 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREAT+IDPQ RLLLE SWEAIE G+DPA+LA S T V Sbjct: 81 SRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGV 140 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGL A Sbjct: 141 FVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTA 200 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH ACRSL DGESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 201 VHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEG 260 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKRLPDA+RDG+R+ A++ GTA NQDG T + PS E Sbjct: 261 CVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEA 320 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G+VEAHGTGTP+GDP+EY SLA VYG PCAL S K+N GH +++G +GL+K IL Sbjct: 321 STVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTIL 380 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +LR+G+VP LHF RL D L EI+T LFVPQ T WP P+R AVSS+GMSGTNVH Sbjct: 381 ALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNVH 439 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS- 482 I+E+AP A PE +P G G LF +S+TS L TA +LA WV+++ ++ Sbjct: 440 AILEQAPVSEPAASGPELTPEAG----GLALFPVSATSAEQLHVTAARLADWVDQNGNAG 495 Query: 483 --VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 V + DL YTL+ RAHRPVRT V A+ EL L ++A Y VGH DRGPVW Sbjct: 496 SRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVW 555 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LL EPVFAAT+ +EPVIA ES FSVTEA++AP+TV+GID+VQP Sbjct: 556 VFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQP 615 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FAVQVALA ++ +YGVRPGA+IGHS+ D RVICRRS+LM+R+ Sbjct: 616 TIFAVQVALAAALK-SYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRI 674 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RGI DVV+SVVASP STV+GGAT+++RDL+A WEQ+DV Sbjct: 675 AGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDV 734 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +AREVAVDVASH+ QV P++PYYSATL+DPRE P G YWV+ Sbjct: 735 LAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVE 794 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DGYRVF EL+PHPLLT+AVEQ A +LDM +A LA MRR + +P Sbjct: 795 NLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLP 854 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+H+AGA +DF+ YP GRL+DAPLP WTH L + + + GA V Sbjct: 855 FGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQA-V 913 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH+WQ VGT A WL DH++HNVAA PGAAYCEM Sbjct: 914 HPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLG 973 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQ LLL +T + + A++ APG++ F V+++Q+GE R A+A LHA E+ Sbjct: 974 ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEM 1033 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PP YD AL AH +S++G +LR+ F G+Q TVLAEVA Sbjct: 1034 PQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGDVTTVLAEVA 1093 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP +IR QQS+Y HPALLDACFQSV + K + GL+LP+GVR LR Y TR+A Sbjct: 1094 LPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKA-TVGGLMLPVGVRRLRNYHSTRSAH 1152 Query: 1141 YCYTRLTKIEPRGG-EADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 YC R+T G EADLDV D+ G VLL V GL + G +E +R ERLLTI W Sbjct: 1153 YCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEW 1212 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 ++ LPE ++ GSWLL+ A D + L DAL + G Q T + S D Sbjct: 1213 ERGELPEVPQIDAGSWLLLSASEA----DPLTAQLADALNAVGAQSTSVASAS-----DV 1263 Query: 1260 VVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRL 1319 R LG +L G VV++ GP G + R+ V LV I RELAEL GE PRL Sbjct: 1264 AQLRSLLGGRLTG---VVVVTGPPTGGLTQ----CGRDYVSQLVGIARELAELPGEPPRL 1316 Query: 1320 FVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVD-EHTDVERVAQQLLS 1378 FVVTR A V D ANLEQAGLRGL+RVI SEHP L T +DVD + T VA QL S Sbjct: 1317 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQS 1376 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GS+EDETAWRNG WY ARL P PL +RRT V+ DG+R+ +R PGDL+SLE V D Sbjct: 1377 GSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFD 1436 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RV PGPG++EVAV+ SS+NFADVL+AFGR+P + QLG+DF H+I Sbjct: 1437 RVAPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRI 1496 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG S GCW TF+ CDA LAVTLP L WY L+DLA I D Sbjct: 1497 GDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD 1556 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA G EIFATAG+ +R +LHD+G+EHVYDSRS EFAEQIR Sbjct: 1557 KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIR 1616 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+TRLGLFPFRR L+ Y Sbjct: 1617 GDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA 1676 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DLAL++ + P VR LL TV+ T +G L P+ THYP+ DAA AIR + A HTGK+V Sbjct: 1677 VDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVV 1736 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+PRTG VPPEQ R DG+Y++T F A +LA AGCGRIVL +RS P Sbjct: 1737 LDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTP 1796 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 +P A + IERL AAGADI VECG+IA+ TA R+V ATA+GLP+RGVLH+AAVVEDATL Sbjct: 1797 SPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATL 1856 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 N+TDELIDR W+PKV+G+WN+H AT QPL+WFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1857 ANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLD 1916 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 FAHWRRAQGLP ++IAWGAW E+GRAT LAEG I P EGA AF+ L+RY R YSGY Sbjct: 1917 AFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY 1976 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PI+G PWL +RS +AE F + GQ KF EL +LP++EW +RRL+ +Q S Sbjct: 1977 APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQIS 2036 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 ++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P I T R LA+++ D L Sbjct: 2037 LLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKI---TTVRGLAEHVCDEL 2093 Query: 2099 A 2099 A Sbjct: 2094 A 2094 >tr|A4KGA7|A4KGA7_MYCTU Tax_Id=395095 SubName: Full=Polyketide beta-ketoacyl synthase pks4;[Mycobacterium tuberculosis str. Haarlem] Length = 2085 Score = 2317 bits (6004), Expect = 0.0 Identities = 1206/2101 (57%), Positives = 1458/2101 (69%), Gaps = 32/2101 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 + T +AVIGM CRLPGGI+SP +LWE+LLRGD+LV E+P DRWD + +YDPEPGVPGRSV Sbjct: 5 TATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSV 64 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREAT+IDPQ RLLLE SWEAIE G+DPA+LA S T V Sbjct: 65 SRWGAFLDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGV 124 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGL A Sbjct: 125 FVGLTHGDYELLSADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTA 184 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH ACRSL DGESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 185 VHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEG 244 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKRLPDA+RDG+R+ A++ GTA NQDG T + PS E Sbjct: 245 CVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVNIAAPSAQAQIAVYQQALAAAGVEA 304 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G+VEAHGTGTP+GDP+EY SLA VYG PCAL S K+N GH +++G +GL+K IL Sbjct: 305 STVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHLQSASGPLGLMKTIL 364 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +LR+G+VP LHF RL D L EI+T LFVPQ T WP P+R AVSS+GMSGTNVH Sbjct: 365 ALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWP-DNTGQPRRAAVSSYGMSGTNVH 423 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDS- 482 I+E+AP A PE +P G G LF +S+TS L TA +LA WV+++ ++ Sbjct: 424 AILEQAPVSEPAASGPELTPEAG----GLALFPVSATSAEQLHVTAARLADWVDQNGNAG 479 Query: 483 --VVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 V + DL YTL+ RAHRPVRT V A+ EL L ++A Y VGH DRGPVW Sbjct: 480 SRVSMRDLGYTLSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVW 539 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQW MG +LL EPVFAAT+ +EPVIA ES FSVTEA++AP+TV+GID+VQP Sbjct: 540 VFSGQGSQWPGMGTELLVAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQP 599 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FAVQVALA ++ +YGVRPGA+IGHS+ D RVICRRS+LM+R+ Sbjct: 600 TIFAVQVALAAALK-SYGVRPGAIIGHSLGEAAAAVVAGALSLHDGLRVICRRSRLMSRI 658 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RGI DVV+SVVASP STV+GGAT+++RDL+A WEQ+DV Sbjct: 659 AGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVGGATQSIRDLVAAWEQQDV 718 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 +AREVAVDVASH+ QV P++PYYSATL+DPRE P G YWV+ Sbjct: 719 LAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPSFTGEYWVE 778 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DGYRVF EL+PHPLLT+AVEQ A +LDM +A LA MRR + +P Sbjct: 779 NLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLP 838 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+H+AGA +DF+ YP GRL+DAPLP WTH L + + + GA V Sbjct: 839 FGLRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQA-V 897 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV LLEEPERH+WQ VGT A WL DH++HNVAA PGAAYCEM Sbjct: 898 HPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLG 957 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD 1020 I FEQ LLL +T + + A++ APG++ F V+++Q+GE R A+A LHA E+ Sbjct: 958 ELSEVRDIKFEQTLLLDEQTVVSSAATIAAPGILQFAVESHQEGEPARRASAMLHALEEM 1017 Query: 1021 CPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVA 1080 PP YD AL AH +S++G +LR+ F G+Q TVLAEVA Sbjct: 1018 PQPPGYDTNALTAAHESSMSGEELRKMFNSLGIQYGPAFSGLVAVHTARGDVTTVLAEVA 1077 Query: 1081 LPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNAR 1140 LP +IR QQS+Y HPALLDACFQSV + K + GL+LP+GVR LR Y TR+A Sbjct: 1078 LPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKA-TVGGLMLPVGVRRLRNYHSTRSAH 1136 Query: 1141 YCYTRLTKIEPRGG-EADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGW 1199 YC R+T G EADLDV D+ G VLL V GL + G +E +R ERLLTI W Sbjct: 1137 YCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDERLLTIEW 1196 Query: 1200 QQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDP 1259 ++ LPE ++ GSWLL+ A D + L DAL + G Q T + S D Sbjct: 1197 ERGELPEVPQIDAGSWLLLSASEA----DPLTAQLADALNAVGAQSTSVASAS-----DV 1247 Query: 1260 VVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRL 1319 R LG +L G VV++ GP G + R+ V LV I RELAEL GE PRL Sbjct: 1248 AQLRSLLGGRLTG---VVVVTGPPTGGLTQ----CGRDYVSQLVGIARELAELPGEPPRL 1300 Query: 1320 FVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVD-EHTDVERVAQQLLS 1378 FVVTR A V D ANLEQAGLRGL+RVI SEHP L T +DVD + T VA QL S Sbjct: 1301 FVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAIDVDNDETVAALVASQLQS 1360 Query: 1379 GSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASD 1438 GS+EDETAWRNG WY ARL P PL +RRT V+ DG+R+ +R PGDL+SLE V D Sbjct: 1361 GSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDGMRLQIRTPGDLESLEFVTFD 1420 Query: 1439 RVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQI 1498 RV PGPG++EVAV+ SS+NFADVL+AFGR+P + QLG+DF H+I Sbjct: 1421 RVAPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRI 1480 Query: 1499 GDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGD 1558 GD VGG S GCW TF+ CDA LAVTLP L WY L+DLA I D Sbjct: 1481 GDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD 1540 Query: 1559 KVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIR 1618 KVLIHS TGGVGQAAI+IARA G EIFATAG+ +R +LHD+G+EHVYDSRS EFAEQIR Sbjct: 1541 KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIR 1600 Query: 1619 RDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYY 1678 DTDGYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+TRLGLFPFRR L+ Y Sbjct: 1601 GDTDGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYA 1660 Query: 1679 LDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLV 1738 +DLAL++ + P VR LL TV+ T +G L P+ THYP+ DAA AIR + A HTGK+V Sbjct: 1661 VDLALLTHSHPHTVRRLLKTVYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVV 1720 Query: 1739 LDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAGCGRIVLTARSQP 1798 LD+PRTG VPPEQ R DG+Y++T F A +LA AGCGRIVL +RS P Sbjct: 1721 LDVPRTGEGVAVVPPEQVRTSRPDGAYLVTGGLGGLGLFLAGELAAAGCGRIVLNSRSTP 1780 Query: 1799 NPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATL 1858 +P A + IERL AAGADI VECG+IA+ TA R+V ATA+GLP+RGVLH+AAVVEDATL Sbjct: 1781 SPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATASGLPVRGVLHAAAVVEDATL 1840 Query: 1859 TNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVD 1918 N+TDELIDR W+PKV+G+WN+H AT QPL+WFCLFSS AAL+GSPGQGAYAAANSW+D Sbjct: 1841 ANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQGAYAAANSWLD 1900 Query: 1919 LFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGY 1978 FAHWRRAQGLP ++IAWGAW E+GRAT LAEG I P EGA AF+ L+RY R YSGY Sbjct: 1901 AFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY 1960 Query: 1979 IPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS 2038 PI+G PWL +RS +AE F + GQ KF EL +LP++EW +RRL+ +Q S Sbjct: 1961 APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQIS 2020 Query: 2039 VILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 ++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P I T R LA+++ D L Sbjct: 2021 LLLRRTIDPDRPLSDYGLDSLGNLELRTRIETETGIRVSPTKI---TTVRGLAEHVCDEL 2077 Query: 2099 A 2099 A Sbjct: 2078 A 2078 >tr|A0R1E8|A0R1E8_MYCS2 Tax_Id=246196 SubName: Full=Mycocerosic acid synthase; EC=2.3.1.111;[Mycobacterium smegmatis] Length = 2111 Score = 2312 bits (5991), Expect = 0.0 Identities = 1203/2127 (56%), Positives = 1479/2127 (69%), Gaps = 38/2127 (1%) Query: 2 ETSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGR 61 + V P+A+IGM CRLPG INSP +LWE+LLRGD+ VTE+P RWD +++YDPEPGVPGR Sbjct: 3 QNCVAPVAIIGMACRLPGAINSPQQLWEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGR 62 Query: 62 SVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSST 121 SVS+WG FLDD A FD EFFGI+EREA +IDPQ RLLLET+WEA+E GL+PA LAGS+T Sbjct: 63 SVSKWGAFLDDPAAFDPEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSAT 122 Query: 122 AVFTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGL 181 VF GLTH DY L A L PY TG + S+ASGRI++ LG+HGPA+T DTACSS L Sbjct: 123 GVFMGLTHNDYAHLAADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAITVDTACSSSL 182 Query: 182 MAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRS 241 A+H+ACRSLHDGESD+ALAGG +VLLEP + SA GMLS TG C +F ADGFV + Sbjct: 183 SAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGMLSPTGHCHAFDTAADGFVSA 242 Query: 242 EGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXX 301 EGC ++ LKRL DA+ DG+RI A+I GTATNQDG T + PS D Sbjct: 243 EGCVVLTLKRLDDAVADGDRILAVIRGTATNQDGRTVNIATPSADAQAKVYRMALKAAGV 302 Query: 302 EPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKA 361 EP T+G+VEAHGTGTP+GDP+E+ SLA VYG PCALGS K+N GH+ ++AG +G++KA Sbjct: 303 EPGTVGLVEAHGTGTPVGDPLEFSSLAEVYGTDGPCALGSIKTNFGHTQSAAGALGVMKA 362 Query: 362 ILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTN 421 +L+L++ ++P LHF RL D + EIETGLFVP+ +TPWPV P+R AVS++G+SGTN Sbjct: 363 VLALQHNVIPQNLHFTRLPDQMAEIETGLFVPETITPWPVRE-GQPRRAAVSAYGLSGTN 421 Query: 422 VHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQD 481 VH ++E+AP SP G+A V F +S++S ALR TA+ LA W+ D Sbjct: 422 VHAVLEQAPESPAETAAEAISPKAGNALV----FPVSASSADALRSTAQHLADWLLRSGD 477 Query: 482 ------SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGD 535 ++ L DLAYTLAR R R R+AV+A D LVEGL +IADG+A+ V + D Sbjct: 478 GNGRGPAIDLGDLAYTLARRRGFRAARSAVLAGDRGTLVEGLRQIADGEAMPQQAVTNDD 537 Query: 536 RGPVWVFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGI 595 RGPVWVFSGQGSQWASMG +LL EP FAA I +LEP+IAAES FSVTEA+TA ETVTGI Sbjct: 538 RGPVWVFSGQGSQWASMGAELLDREPAFAAAIAELEPLIAAESDFSVTEALTASETVTGI 597 Query: 596 DKVQPSVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSK 655 D+VQP++FAVQVALA M +++GV PGAVIGHSM D +VICRR++ Sbjct: 598 DRVQPTIFAVQVALAAAM-RSHGVVPGAVIGHSMGEVAASVVSGALSLEDGVKVICRRTR 656 Query: 656 LMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQW 715 LM R+AGSGAM VELPA+QV SEL +RG+DDVV+SVVASPQSTV+GGAT +VR+LI W Sbjct: 657 LMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQSTVVGGATASVRELIEMW 716 Query: 716 EQRDVMAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNG 775 E R VMARE+AVDVASHS QV P++PYYSATL+DPR+ + Sbjct: 717 ESRGVMAREIAVDVASHSPQVDPILDDLIEALADLDPAEPEIPYYSATLYDPRDYADYDA 776 Query: 776 AYWVDNLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRR 835 YW DNLR+TV+F+AAVQAA+EDG+RVFAELSPHPLLTH VEQTAR+LDM +A A MRR Sbjct: 777 YYWADNLRHTVRFSAAVQAALEDGHRVFAELSPHPLLTHPVEQTARSLDMPLAVFAAMRR 836 Query: 836 EQSMPYGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGA 895 +Q MP+GL G +ADLHSAGAA+DF+ LYP GRLLDAPLP WTH L +D + E A G Sbjct: 837 QQEMPHGLLGFVADLHSAGAAVDFSVLYPTGRLLDAPLPAWTHSTLLLDRE-LESSAPGV 895 Query: 896 CTVTVHPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXX 955 +V+VHPLLGSHV L +EPE H+WQGDVGT A WL+DH+VH VA LPGAAYCEM Sbjct: 896 PSVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAYCEMALAAV 955 Query: 956 XXXXXXXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLH 1015 + F MLLL TP+ A+V APG F V+ +Q G++ + ATA L Sbjct: 956 TPVLGDTGEVHDLKFHDMLLLDDATPVWVSAAVTAPGTAEFGVETHQSGDRTQRATAVLR 1015 Query: 1016 AAEDDCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTV 1075 D P A+ I ALL AHPN V+G +LR F G+ TV Sbjct: 1016 GDVDAERPAAHSIDALLAAHPNRVDGDELRAGFGTVGIGHGAAFAGLSEAYVATAAEPTV 1075 Query: 1076 LAEVALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRP 1135 +A VALP +R Q Y +HPALLDACFQSV A + + S G+LLPLGVR LR Y Sbjct: 1076 VAAVALPGPLRSGQRGYTVHPALLDACFQSVIAHPEVQNIAS--GMLLPLGVRRLRAYGS 1133 Query: 1136 TRNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLL 1195 TRN RYC +R+ K + G EADL++LD G VLL+ GL +GTG +++ E +R L ERLL Sbjct: 1134 TRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQLGTGNSDKAEEERLLDERLL 1193 Query: 1196 TIGWQQRTLPE---SVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLS 1252 TI WQQR LP S V+ GSWL+I + P A+ + AL G T ++ Sbjct: 1194 TIEWQQRELPRPEGSETVDAGSWLVILAGDDDENPR--AAGVVSALIG---AGMPTTTMA 1248 Query: 1253 WLIQDDPVVSRERLGRQLRGRD--GVVILCGPRAGAPDEQSLLA----AREQVRHLVRII 1306 W D L +L + GV ++ G D + A + VRHLVRI Sbjct: 1249 WSHDADHDAQAAALTARLDEQPLAGVAVIVGDSETGTDAHDVGADARRGADHVRHLVRIA 1308 Query: 1307 RELAELEGELPRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEH 1366 R LA+ GE PRL+VVT ++Q V D LE +GLRGL+RV+ EHP LR T +DVD+ Sbjct: 1309 RTLADAVGEPPRLYVVTHRSQHVLDTDEPYLEHSGLRGLIRVVGMEHPRLRATQIDVDDS 1368 Query: 1367 TDVERVAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKP 1426 T E + +QLLSGS EDETAWR+G WY ARL PSPL +RRT V + +G+R+ VR P Sbjct: 1369 TAHEALVRQLLSGSPEDETAWRDGQWYAARLCPSPLRAAERRTAVADNASEGMRLVVRNP 1428 Query: 1427 GDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXX 1486 GDL+S+ELV +R PGPGQ+EVAV SSINFADVL+AFGR P D R P+LG +F Sbjct: 1429 GDLESMELVTFERGTPGPGQIEVAVKASSINFADVLVAFGRCPSFDGRLPELGSEFGGVV 1488 Query: 1487 XXXXXXXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWY 1546 H++GDRVGG S GCW F+TC+A+LA LP G+++ + W Sbjct: 1489 TAVGPGVTTHRVGDRVGGVSANGCWSNFVTCEADLATKLPEGISEHEAAAVGLAYGTVWL 1548 Query: 1547 GLNDLAGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVY 1606 GL +LA + GDK+LIHSATGGVGQAAI++ARA GAEI+ATAG+ +R +L D GIEHVY Sbjct: 1549 GLTELARMSAGDKILIHSATGGVGQAAIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVY 1608 Query: 1607 DSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLG 1666 DSR+ FA+QIR DTDGYGVDIVLNS+TG AQRAGLELL FGGRFVEIGK D+Y +TRLG Sbjct: 1609 DSRTTAFADQIRTDTDGYGVDIVLNSVTGPAQRAGLELLAFGGRFVEIGKRDIYADTRLG 1668 Query: 1667 LFPFRRGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIR 1726 LFPFRR L+FY +DLALM+VT P ++R+LLATV+ L ADG L PE THYPL +AA AIR Sbjct: 1669 LFPFRRNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADGTLPLPEITHYPLEEAATAIR 1728 Query: 1727 AMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLAEAG 1786 M A+HTGKLV+DIP TG V VPPEQ PV+R DG+Y+IT F A ++A AG Sbjct: 1729 IMGGAQHTGKLVIDIPDTGQSQVVVPPEQVPVFRGDGAYVITGGLGGLGLFLAERMAAAG 1788 Query: 1787 CGRIVLTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGV 1846 CGRIV+ +RS P+ ++ + IE + A GADIVVECG+IAEP TA RLV AAT TGLPLRGV Sbjct: 1789 CGRIVVNSRSAPSTRSSEIIELIRATGADIVVECGDIAEPDTALRLVAAATQTGLPLRGV 1848 Query: 1847 LHSAAVVEDATLTNITDELIDRDWSPKVYGSWNLHCAT-IGQP----LDWFCLFSSGAAL 1901 LH+AAVVEDATL NITDEL++ DW+PKVYG+WNLH A G P LDWFC FSS AAL Sbjct: 1849 LHAAAVVEDATLANITDELVEHDWAPKVYGAWNLHQAVQSGGPATSELDWFCAFSSAAAL 1908 Query: 1902 LGSPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEG 1961 +GSPGQGAYAAANSW+D F WRRAQGLP ++IAWGAWGE+GR T +AE G+ I PDEG Sbjct: 1909 VGSPGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGEIGRGTAMAE-GDNAIAPDEG 1967 Query: 1962 AYAFEMLVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALP 2021 AYAFE ++R+DR Y+GY P+LGA WL +RSP+AE+F + QG+ K R EL ALP Sbjct: 1968 AYAFEAILRHDRVYNGYAPVLGASWLTAFAQRSPFAELFLADTQGASETRKLRSELAALP 2027 Query: 2022 QDEWSGRLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVI 2081 ++EW LRRL+ EQ ++LRRT+D DR EYGLDSLG LE+RT IE+ETG+R++ + Sbjct: 2028 REEWPTHLRRLIAEQVGLLLRRTVDPDRPLSEYGLDSLGHLELRTRIETETGVRVSAMDM 2087 Query: 2082 ATNNTARALAQYLADTLAEEEGVAAPA 2108 T R LAQ L + L ++ V+AP+ Sbjct: 2088 ---TTIRGLAQRLCEMLDTDDAVSAPS 2111 >tr|Q49624|Q49624_MYCLE Tax_Id=1769 (pks3)SubName: Full=Mycocerosic acid synthase (Polyketide synthase); SubName: Full=MasA;[Mycobacterium leprae] Length = 2118 Score = 2306 bits (5975), Expect = 0.0 Identities = 1208/2130 (56%), Positives = 1470/2130 (69%), Gaps = 41/2130 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 +VTP+AVIGM CRLPGGI+SP +LWE+LLRGD+LVTE+P +RWD D +YDPEPGVPGRSV Sbjct: 5 NVTPVAVIGMACRLPGGIDSPQRLWEALLRGDDLVTEIPKERWDADLYYDPEPGVPGRSV 64 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREA +IDPQ RLLLETSW+AIE GLDPA+LAGS+T V Sbjct: 65 SRWGAFLDDVGGFDCDFFGMTEREAIAIDPQHRLLLETSWDAIEHAGLDPATLAGSATGV 124 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGLMA Sbjct: 125 FVGLTHGDYELLSADCGATEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLMA 184 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH A SL GESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 185 VHQARGSLDCGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDVAADGFVSGEG 244 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKR+PDA RDG+RI A++ GTA NQDG T + PSE +P Sbjct: 245 CVVLLLKRMPDAERDGDRILAVLRGTAANQDGHTVHIAAPSEQAQIAVYHKALAVGGVDP 304 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G++EAHGTGTP+GDPIEY SLA VYG CAL S K+N GH +++G +G++KAIL Sbjct: 305 TTVGLIEAHGTGTPVGDPIEYASLAAVYGTAGRCALASTKTNFGHMQSTSGPLGMMKAIL 364 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +L++G+VP LHF RL D L EI T LFVPQ TPWPV P+R AVSS+GMSGTNVH Sbjct: 365 ALQHGVVPKNLHFTRLPDQLAEITTELFVPQVNTPWPVD-VQQPRRAAVSSYGMSGTNVH 423 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDSV 483 I+E+AP E D P S G LF LS+TS+ LR TA ++A WV+EH Sbjct: 424 AILEQAP-ENSGKDSPAVSKVNGPL-----LFPLSATSVEQLRATAARMADWVDEHGSGT 477 Query: 484 V---LSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 L DL YTL+R R +RPVRT V+A+ EL GL EIA + Y + VG DRGPVW Sbjct: 478 KHTGLWDLGYTLSRRRGYRPVRTMVLASSFAELSRGLREIAGSEIPYQSAVGQDDRGPVW 537 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA MG +L A EPVFAA I +EPVI ES FSVTEA+T E VTGID+VQP Sbjct: 538 VFSGQGSQWAGMGAELFAKEPVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTGIDRVQP 597 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS+LM+RV Sbjct: 598 TIFAIQVALAATMK-SYGVYPGAVIGHSLGEAAAAVAAGALSCEDGLRVICRRSQLMSRV 656 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RG+ DVV++VVASP STV+GG T+ +R L+A W+ +DV Sbjct: 657 AGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTSTVVGGDTQAIRHLLAAWQAQDV 716 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 M REVAVDVASH+ QV PKVPYYSATL+DPRE P G YW + Sbjct: 717 MVREVAVDVASHTPQVEPILDDLVETLADLKPTEPKVPYYSATLWDPRERPSFTGEYWAE 776 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DG+RVF EL+PHPLLT+A+EQ A +LDM V+ALA MRREQ +P Sbjct: 777 NLRYTVRFAAAVQAALKDGFRVFGELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELP 836 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+HSAGA +DF+ YP G L+DAPLP WT L + + + A GA V Sbjct: 837 FGLRGFIADVHSAGALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAVQAV 896 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV L EEPERH+WQG VGT A WL DHQ+H+VAA PGAAYCEM Sbjct: 897 HPLLGAHVHLFEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAYCEMALTAARVTLG 956 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAED- 1019 I FEQ LLL ET + A+V APGV+ F V+ ++GE++R A+A L A ED Sbjct: 957 EASEVRDIKFEQTLLLDRETMASSAATVSAPGVLEFAVETYEEGERVRRASAVLRALEDR 1016 Query: 1020 -DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXS---GTV 1075 + P ++ I AL+ +HP G DLR +F G+Q + TV Sbjct: 1017 VNQQPASHSIDALIASHPLRTEGADLRATFDAIGIQYGLAFSGLTAVYTAAGTNEDVSTV 1076 Query: 1076 LAEVALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRP 1135 LAEVALP +IR QQ+SY HPALLDACFQSV + K G+ GLLLP+ VR L Y Sbjct: 1077 LAEVALPGAIRSQQASYTSHPALLDACFQSVIVAPEVQKAGA-GGLLLPVYVRRLLNYHS 1135 Query: 1136 TRNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLL 1195 RNA+YC TR+ E DL+VLD+ GAVLL V GL + G +E +R L ERL Sbjct: 1136 MRNAQYCLTRVKTSRAGECEVDLEVLDQSGAVLLLVEGLRLAGGASEHECANRVLDERLF 1195 Query: 1196 TIGWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGT--------- 1246 T+ W+ R LPE E GSWL++ ++ D L DAL + G T Sbjct: 1196 TVEWEPRELPEVTQRERGSWLVL----GASAEDPLVQQLGDALNADGGHCTAVSLPLGQI 1251 Query: 1247 ECTNLSWLIQDDPVVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRII 1306 + L L+ D V S G L+G GVV++ P A + +L R+ V HL+ I+ Sbjct: 1252 DTAQLCSLLSRDGVSSSIGHGA-LKGLTGVVVVTAPPATVAESPALRRGRDYVSHLITIV 1310 Query: 1307 RELAELEGELPRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEH 1366 RE++EL GE PRLFVVTR A +++GD ANLEQ GLRGL+RVI SEHP L T +DV+E Sbjct: 1311 REISELPGERPRLFVVTRNAASIKTGDLANLEQVGLRGLIRVIDSEHPYLSVTQIDVEET 1370 Query: 1367 ---TDVERVAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHV 1423 T +VA+QL SGS+EDET WR+G+WY ARL P PL +RRTVV+ EHDG+R+ + Sbjct: 1371 NQATIATQVARQLRSGSDEDETGWRDGEWYTARLRPGPLRQAERRTVVVQNEHDGMRLEI 1430 Query: 1424 RKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFX 1483 R PGDL SLE VA DRVPPGPG++EVAV+ S++NFADVL+AFGR+P + LG+DF Sbjct: 1431 RTPGDLDSLEFVAFDRVPPGPGEIEVAVTASTVNFADVLVAFGRYPTFEGYCQLLGIDFA 1490 Query: 1484 XXXXXXXXXXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXX 1543 H++GDRVGG S GCW TF+ CDA AVTL + E+ Sbjct: 1491 GVVSAVGLNVTDHKVGDRVGGVSRNGCWTTFVICDARHAVTLSPEVPLEEAAAVPTVAAT 1550 Query: 1544 XWYGLNDLAGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIE 1603 WYGL+DLA I DKVLIHS TGGVGQAAI+IARA G EIFATAG+P +R +L D GIE Sbjct: 1551 AWYGLHDLARISQTDKVLIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDKGIE 1610 Query: 1604 HVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNT 1663 HVYDSRS+EFAEQI RDT GYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+T Sbjct: 1611 HVYDSRSLEFAEQIHRDTKGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDT 1670 Query: 1664 RLGLFPFRRGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAAN 1723 RLGLFPFRR L+ Y +DLAL++ T PD VR LL TV+ TA+GVL P+ THYP+ + AN Sbjct: 1671 RLGLFPFRRNLSLYAVDLALLTYTHPDTVRRLLTTVYQRTAEGVLPVPQTTHYPIHNTAN 1730 Query: 1724 AIRAMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLA 1783 A+R ++ A HTGK++LD+P TGS VPPEQ +R DG+YI+T F +++A Sbjct: 1731 AVRLVAGAGHTGKVLLDVPHTGSSVAVVPPEQVRTFRADGAYIVTGGLTGLGLFLGTEMA 1790 Query: 1784 EAGCGRIVLTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPL 1843 AGCGRIVL +RS PNP+A++TIERL A GADI VECG+IAEP ADRLV AAT +GLP+ Sbjct: 1791 AAGCGRIVLNSRSAPNPQAQETIERLRAGGADIQVECGDIAEPRVADRLVVAATQSGLPV 1850 Query: 1844 RGVLHSAAVVEDATLTNITDELIDRDWSPKVYGSWNLHCA----TIGQPLDWFCLFSSGA 1899 RGVLH+A VVEDATLTN+TD+LIDR W+PKVYG+WNLH A Q LDWFC FS+ A Sbjct: 1851 RGVLHAAGVVEDATLTNVTDDLIDRCWAPKVYGAWNLHQALQEGKTAQLLDWFCSFSTAA 1910 Query: 1900 ALLGSPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPD 1959 AL+GSPGQGAYAAANSW+D F++WRRAQGL + IAWGAWGE+G AT LAE + I P Sbjct: 1911 ALVGSPGQGAYAAANSWLDGFSYWRRAQGLASTTIAWGAWGELGLATALAEMAGVAIAPT 1970 Query: 1960 EGAYAFEMLVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLA 2019 EGA F+ L+RY+RPYS Y PI+ PWL + S +AE F S QG + SKF EL Sbjct: 1971 EGARVFQTLLRYNRPYSCYAPIMETPWLKSFAQHSRFAEAFRSISQGQKDKSKFLAELKV 2030 Query: 2020 LPQDEWSGRLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPK 2079 LP+DEW +RRL+ EQ S++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P Sbjct: 2031 LPRDEWPSMIRRLVSEQISLLLRRTIDPDRLLSDYGLDSLGNLELRTRIETETGIRISPT 2090 Query: 2080 VIATNNTARALAQYLADTLAEEEGVAAPAA 2109 I T R+LA++L + LA E +A A Sbjct: 2091 KI---TTIRSLAEHLCEELAATEAESAVTA 2117 >tr|B8ZR93|B8ZR93_MYCLB Tax_Id=561304 (pks3)SubName: Full=Mycocerosic acid synthase (Polyketide synthase);[Mycobacterium leprae] Length = 2118 Score = 2306 bits (5975), Expect = 0.0 Identities = 1208/2130 (56%), Positives = 1470/2130 (69%), Gaps = 41/2130 (1%) Query: 4 SVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSV 63 +VTP+AVIGM CRLPGGI+SP +LWE+LLRGD+LVTE+P +RWD D +YDPEPGVPGRSV Sbjct: 5 NVTPVAVIGMACRLPGGIDSPQRLWEALLRGDDLVTEIPKERWDADLYYDPEPGVPGRSV 64 Query: 64 SRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV 123 SRWG FLDDV GFD +FFG++EREA +IDPQ RLLLETSW+AIE GLDPA+LAGS+T V Sbjct: 65 SRWGAFLDDVGGFDCDFFGMTEREAIAIDPQHRLLLETSWDAIEHAGLDPATLAGSATGV 124 Query: 124 FTGLTHEDYLVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMA 183 F GLTH DY +L+ G PY TG +NS ASGR+++TLGLHGPA+T DTACSSGLMA Sbjct: 125 FVGLTHGDYELLSADCGATEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLMA 184 Query: 184 VHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEG 243 VH A SL GESDLALAGG V LEP SV+ S QGMLS TGRC +F ADGFV EG Sbjct: 185 VHQARGSLDCGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDVAADGFVSGEG 244 Query: 244 CAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEP 303 C ++LLKR+PDA RDG+RI A++ GTA NQDG T + PSE +P Sbjct: 245 CVVLLLKRMPDAERDGDRILAVLRGTAANQDGHTVHIAAPSEQAQIAVYHKALAVGGVDP 304 Query: 304 ETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAIL 363 T+G++EAHGTGTP+GDPIEY SLA VYG CAL S K+N GH +++G +G++KAIL Sbjct: 305 TTVGLIEAHGTGTPVGDPIEYASLAAVYGTAGRCALASTKTNFGHMQSTSGPLGMMKAIL 364 Query: 364 SLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVH 423 +L++G+VP LHF RL D L EI T LFVPQ TPWPV P+R AVSS+GMSGTNVH Sbjct: 365 ALQHGVVPKNLHFTRLPDQLAEITTELFVPQVNTPWPVD-VQQPRRAAVSSYGMSGTNVH 423 Query: 424 VIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDSV 483 I+E+AP E D P S G LF LS+TS+ LR TA ++A WV+EH Sbjct: 424 AILEQAP-ENSGKDSPAVSKVNGPL-----LFPLSATSVEQLRATAARMADWVDEHGSGT 477 Query: 484 V---LSDLAYTLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVW 540 L DL YTL+R R +RPVRT V+A+ EL GL EIA + Y + VG DRGPVW Sbjct: 478 KHTGLWDLGYTLSRRRGYRPVRTMVLASSFAELSRGLREIAGSEIPYQSAVGQDDRGPVW 537 Query: 541 VFSGQGSQWASMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP 600 VFSGQGSQWA MG +L A EPVFAA I +EPVI ES FSVTEA+T E VTGID+VQP Sbjct: 538 VFSGQGSQWAGMGAELFAKEPVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTGIDRVQP 597 Query: 601 SVFAVQVALATTMEQTYGVRPGAVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRV 660 ++FA+QVALA TM+ +YGV PGAVIGHS+ D RVICRRS+LM+RV Sbjct: 598 TIFAIQVALAATMK-SYGVYPGAVIGHSLGEAAAAVAAGALSCEDGLRVICRRSQLMSRV 656 Query: 661 AGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDV 720 AGSGAM SVELP +QV SEL RG+ DVV++VVASP STV+GG T+ +R L+A W+ +DV Sbjct: 657 AGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTSTVVGGDTQAIRHLLAAWQAQDV 716 Query: 721 MAREVAVDVASHSSQVXXXXXXXXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVD 780 M REVAVDVASH+ QV PKVPYYSATL+DPRE P G YW + Sbjct: 717 MVREVAVDVASHTPQVEPILDDLVETLADLKPTEPKVPYYSATLWDPRERPSFTGEYWAE 776 Query: 781 NLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP 840 NLR TV+FAAAVQAA++DG+RVF EL+PHPLLT+A+EQ A +LDM V+ALA MRREQ +P Sbjct: 777 NLRYTVRFAAAVQAALKDGFRVFGELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELP 836 Query: 841 YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV 900 +GLRG +AD+HSAGA +DF+ YP G L+DAPLP WT L + + + A GA V Sbjct: 837 FGLRGFIADVHSAGALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAVQAV 896 Query: 901 HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXX 960 HPLLG+HV L EEPERH+WQG VGT A WL DHQ+H+VAA PGAAYCEM Sbjct: 897 HPLLGAHVHLFEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAYCEMALTAARVTLG 956 Query: 961 XXXXXXXIAFEQMLLLAAETPIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAED- 1019 I FEQ LLL ET + A+V APGV+ F V+ ++GE++R A+A L A ED Sbjct: 957 EASEVRDIKFEQTLLLDRETMASSAATVSAPGVLEFAVETYEEGERVRRASAVLRALEDR 1016 Query: 1020 -DCPPPAYDIAALLEAHPNSVNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXS---GTV 1075 + P ++ I AL+ +HP G DLR +F G+Q + TV Sbjct: 1017 VNQQPASHSIDALIASHPLRTEGADLRATFDAIGIQYGLAFSGLTAVYTAAGTNEDVSTV 1076 Query: 1076 LAEVALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRP 1135 LAEVALP +IR QQ+SY HPALLDACFQSV + K G+ GLLLP+ VR L Y Sbjct: 1077 LAEVALPGAIRSQQASYTSHPALLDACFQSVIVAPEVQKAGA-GGLLLPVYVRRLLNYHS 1135 Query: 1136 TRNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLL 1195 RNA+YC TR+ E DL+VLD+ GAVLL V GL + G +E +R L ERL Sbjct: 1136 MRNAQYCLTRVKTSRAGECEVDLEVLDQSGAVLLLVEGLRLAGGASEHECANRVLDERLF 1195 Query: 1196 TIGWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGT--------- 1246 T+ W+ R LPE E GSWL++ ++ D L DAL + G T Sbjct: 1196 TVEWEPRELPEVTQRERGSWLVL----GASAEDPLVQQLGDALNADGGHCTAVSLPLGQI 1251 Query: 1247 ECTNLSWLIQDDPVVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRII 1306 + L L+ D V S G L+G GVV++ P A + +L R+ V HL+ I+ Sbjct: 1252 DTAQLCSLLSRDGVSSSIGHGA-LKGLTGVVVVTAPPATVAESPALRRGRDYVSHLITIV 1310 Query: 1307 RELAELEGELPRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEH 1366 RE++EL GE PRLFVVTR A +++GD ANLEQ GLRGL+RVI SEHP L T +DV+E Sbjct: 1311 REISELPGERPRLFVVTRNAASIKTGDLANLEQVGLRGLIRVIDSEHPYLSVTQIDVEET 1370 Query: 1367 ---TDVERVAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHV 1423 T +VA+QL SGS+EDET WR+G+WY ARL P PL +RRTVV+ EHDG+R+ + Sbjct: 1371 NQATIATQVARQLRSGSDEDETGWRDGEWYTARLRPGPLRQAERRTVVVQNEHDGMRLEI 1430 Query: 1424 RKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFX 1483 R PGDL SLE VA DRVPPGPG++EVAV+ S++NFADVL+AFGR+P + LG+DF Sbjct: 1431 RTPGDLDSLEFVAFDRVPPGPGEIEVAVTASTVNFADVLVAFGRYPTFEGYCQLLGIDFA 1490 Query: 1484 XXXXXXXXXXXXHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXX 1543 H++GDRVGG S GCW TF+ CDA AVTL + E+ Sbjct: 1491 GVVSAVGLNVTDHKVGDRVGGVSRNGCWTTFVICDARHAVTLSPEVPLEEAAAVPTVAAT 1550 Query: 1544 XWYGLNDLAGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIE 1603 WYGL+DLA I DKVLIHS TGGVGQAAI+IARA G EIFATAG+P +R +L D GIE Sbjct: 1551 AWYGLHDLARISQTDKVLIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDKGIE 1610 Query: 1604 HVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNT 1663 HVYDSRS+EFAEQI RDT GYGVD+VLNSL GAAQRAG+ELL FGGRFVEIGK D+YG+T Sbjct: 1611 HVYDSRSLEFAEQIHRDTKGYGVDVVLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDT 1670 Query: 1664 RLGLFPFRRGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAAN 1723 RLGLFPFRR L+ Y +DLAL++ T PD VR LL TV+ TA+GVL P+ THYP+ + AN Sbjct: 1671 RLGLFPFRRNLSLYAVDLALLTYTHPDTVRRLLTTVYQRTAEGVLPVPQTTHYPIHNTAN 1730 Query: 1724 AIRAMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLA 1783 A+R ++ A HTGK++LD+P TGS VPPEQ +R DG+YI+T F +++A Sbjct: 1731 AVRLVAGAGHTGKVLLDVPHTGSSVAVVPPEQVRTFRADGAYIVTGGLTGLGLFLGTEMA 1790 Query: 1784 EAGCGRIVLTARSQPNPKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPL 1843 AGCGRIVL +RS PNP+A++TIERL A GADI VECG+IAEP ADRLV AAT +GLP+ Sbjct: 1791 AAGCGRIVLNSRSAPNPQAQETIERLRAGGADIQVECGDIAEPRVADRLVVAATQSGLPV 1850 Query: 1844 RGVLHSAAVVEDATLTNITDELIDRDWSPKVYGSWNLHCA----TIGQPLDWFCLFSSGA 1899 RGVLH+A VVEDATLTN+TD+LIDR W+PKVYG+WNLH A Q LDWFC FS+ A Sbjct: 1851 RGVLHAAGVVEDATLTNVTDDLIDRCWAPKVYGAWNLHQALQEGKTAQLLDWFCSFSTAA 1910 Query: 1900 ALLGSPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPD 1959 AL+GSPGQGAYAAANSW+D F++WRRAQGL + IAWGAWGE+G AT LAE + I P Sbjct: 1911 ALVGSPGQGAYAAANSWLDGFSYWRRAQGLASTTIAWGAWGELGLATALAEMAGVAIAPT 1970 Query: 1960 EGAYAFEMLVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLA 2019 EGA F+ L+RY+RPYS Y PI+ PWL + S +AE F S QG + SKF EL Sbjct: 1971 EGARVFQTLLRYNRPYSCYAPIMETPWLKSFAQHSRFAEAFRSISQGQKDKSKFLAELKV 2030 Query: 2020 LPQDEWSGRLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPK 2079 LP+DEW +RRL+ EQ S++LRRTID DR +YGLDSLG LE+RT IE+ETGIR++P Sbjct: 2031 LPRDEWPSMIRRLVSEQISLLLRRTIDPDRLLSDYGLDSLGNLELRTRIETETGIRISPT 2090 Query: 2080 VIATNNTARALAQYLADTLAEEEGVAAPAA 2109 I T R+LA++L + LA E +A A Sbjct: 2091 KI---TTIRSLAEHLCEELAATEAESAVTA 2117 >tr|A0QCC7|A0QCC7_MYCA1 Tax_Id=243243 SubName: Full=Mycocerosic acid synthase; EC=2.3.1.111;[Mycobacterium avium] Length = 2089 Score = 2300 bits (5961), Expect = 0.0 Identities = 1205/2109 (57%), Positives = 1458/2109 (69%), Gaps = 54/2109 (2%) Query: 31 LLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVSRWGGFLDDVAGFDAEFFGISEREATS 90 +LRGD+LV E+P DRWD D +YDPEPGVPGRSV+RWG FLDDV GFD +FFG++EREAT+ Sbjct: 1 MLRGDDLVGEIPADRWDADLYYDPEPGVPGRSVTRWGAFLDDVGGFDCDFFGMTEREATA 60 Query: 91 IDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVFTGLTHEDYLVLTTAAGGLASPYVVTG 150 +DPQ RLLLETSW+AIE GLDPASLAGS T VF GLTH DY +L+ G PY G Sbjct: 61 VDPQHRLLLETSWDAIEHAGLDPASLAGSQTGVFVGLTHGDYELLSADCGAAEGPYGFAG 120 Query: 151 LNNSVASGRISHTLGLHGPAMTFDTACSSGLMAVHLACRSLHDGESDLALAGGCAVLLEP 210 +NS ASGR+++TLGLHGPA+T DTACSSGLMAVH AC SL GESDL LAGG V LEP Sbjct: 121 TSNSFASGRVAYTLGLHGPAVTVDTACSSGLMAVHQACGSLGGGESDLTLAGGVVVTLEP 180 Query: 211 HASVAASAQGMLSSTGRCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRIFAMILGTA 270 SV+ S QGMLS TGRC +F +ADGFV EGC M+LLKRL DA RDG+RI A++ GTA Sbjct: 181 RKSVSGSLQGMLSPTGRCHAFDVNADGFVSGEGCVMLLLKRLDDARRDGDRILAVLRGTA 240 Query: 271 TNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEPETIGVVEAHGTGTPIGDPIEYRSLARV 330 NQDG T + PSE + T+G+VEAHGTGTP+GDPIEY SLA V Sbjct: 241 ANQDGRTVNISAPSETAQVAVYRKALQAADIDATTVGLVEAHGTGTPVGDPIEYSSLAAV 300 Query: 331 YGAGTPCALGSAKSNMGHSTASAGTVGLIKAILSLRNGLVPPLLHFDRLSDDLTEIETGL 390 YG PC LGS K+N GH +++G +G++KAIL+L++G+VP LHF RL D++ I T L Sbjct: 301 YGTDGPCVLGSVKTNFGHLQSASGPLGMMKAILALQHGVVPRNLHFTRLPDEMARINTEL 360 Query: 391 FVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVHVIVEEAPSEACAPDV-PETSPGTGDAT 449 FVPQE TPW G++ P+R AVSS+GMSGTNVH I+EEAP+ A A PET Sbjct: 361 FVPQENTPWTSNGHH-PRRAAVSSYGMSGTNVHAILEEAPAPAAASSAAPET-------- 411 Query: 450 VGRQLFMLSSTSIAALRETARQLATWVEEHQDSVV-------LSDLAYTLARGRAHRPVR 502 VG LF LSSTS LR TA +LA W++E + L DL YTL R RAHRPVR Sbjct: 412 VGPLLFPLSSTSAEQLRVTAARLAAWLDEQAGDALAGLRGWGLRDLGYTLTRRRAHRPVR 471 Query: 503 TAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVFSGQGSQWASMGVQLLANEPV 562 T V A+ EL L +ADGD Y VG GDRGPVWVFSGQGSQW+ MG +LL EPV Sbjct: 472 TVVSASGFAELRTELRAVADGDIPYQPAVGQGDRGPVWVFSGQGSQWSQMGAELLDKEPV 531 Query: 563 FAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSVFAVQVALATTMEQTYGVRPG 622 FAATI +EP+IAAES FSVT A++AP VTGIDKVQP++FA+QVALA TM+ +YGVRPG Sbjct: 532 FAATIAAVEPLIAAESGFSVTRALSAPPAVTGIDKVQPTIFAMQVALAETMK-SYGVRPG 590 Query: 623 AVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAGSGAMGSVELPAKQVNSELMA 682 AVIGHS+ D +VICRRS+LM R+AG GAM SVELP +QV SEL Sbjct: 591 AVIGHSLGECAAAVVAGGLSLGDGVKVICRRSRLMARIAGRGAMASVELPGQQVLSELSI 650 Query: 683 RGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVXXXXXX 742 RGI DVV+SVVASP STV+GG E +R+L+A W+Q+DVMAREVAVDVASHS QV Sbjct: 651 RGISDVVLSVVASPTSTVVGGDAEAIRELVAAWQQQDVMAREVAVDVASHSPQVESILDE 710 Query: 743 XXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNLRNTVQFAAAVQAAMEDGYRV 802 P+VPYYSATL++PRE P G YW +NLR+TV+FAAAVQAA++DG+RV Sbjct: 711 LVEVLAELEPTAPEVPYYSATLWNPRERPSFGGDYWAENLRHTVRFAAAVQAALKDGFRV 770 Query: 803 FAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLRGLLADLHSAGAALDFAAL 862 F EL+PHPLLTHAVEQ A +LD+ +AALA MRREQ +P GLRG + DLHS+GA +DF+ Sbjct: 771 FGELAPHPLLTHAVEQNAASLDVPIAALAAMRREQELPLGLRGFVGDLHSSGALVDFSVQ 830 Query: 863 YPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHPLLGSHVRLLEEPERHIWQGD 922 YPAGRL+DAPLP W H RL + + QRA G+ VHPLLG+HV L EEPERH+WQG+ Sbjct: 831 YPAGRLVDAPLPTWAHRRLMLRRESV-QRAHGSSVQAVHPLLGAHVHLREEPERHVWQGE 889 Query: 923 VGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXXXXXXXIAFEQMLLLAAETPI 982 VGT A WLADHQ+H VAA PGA YCEM + FEQ LLLA T + Sbjct: 890 VGTDAHPWLADHQIHGVAAFPGAGYCEMALAAAAATLGERAEVRDVTFEQTLLLAGRTEV 949 Query: 983 DAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDD----CPPPAYDIAALLEAHPNS 1038 + A+V PG + F V ++DGE++R A A LHA + PPA+D+A L+ HP+ Sbjct: 950 SSTATVTGPGRLEFTVDTHEDGERIRRAGAVLHALPPEHGGETGPPAHDVATLIADHPSR 1009 Query: 1039 VNGTDLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVALPASIRFQQSSYQIHPAL 1098 + G +LR++F G+Q GTVLAEVALP +IR QQS Y HPAL Sbjct: 1010 IEGAELRKAFGAVGIQYGPAFSGLAAVSVGDRDVGTVLAEVALPGAIRSQQSGYGAHPAL 1069 Query: 1099 LDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNARYCYTRLTKIEPRGGEADL 1158 LDAC QSV A + + G+ GLLLP+GVR LR Y TRNA YC TR+T P EAD+ Sbjct: 1070 LDACLQSVIAAPEVQRAGA-GGLLLPVGVRRLRNYHSTRNAHYCLTRITSSRPGECEADV 1128 Query: 1159 DVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQQRTLPESVHVEPGSWLLI 1218 DVLD+ G VLL V GL + +E R L +RLLTI W+ R LPE+ EPGSWLL+ Sbjct: 1129 DVLDQSGTVLLTVEGLRLAGAASEHEHAQRLLDDRLLTIEWEARELPEAPQGEPGSWLLL 1188 Query: 1219 DTFNASAIPDMWAST-LTDALKSYGTQGTECTNLSWLIQDDPVVSRERLGRQLRGRD--- 1274 +A++ D +T L D LK T G +C +S V E L L G + Sbjct: 1189 SACDAASNGDDALTTQLADVLK---TDGAQCRTVSL---PPGAVDTEELRSLLSGGEPGG 1242 Query: 1275 ----------GVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLFVVTR 1324 GVV++ + A + R+ V HL + REL+EL GE PRLFV+TR Sbjct: 1243 NGHRPLQRLTGVVVVAAA-SEADHPAAPRRGRDYVSHLATVARELSELPGESPRLFVLTR 1301 Query: 1325 QAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGSEEDE 1384 A +V +GDA NL QAGLRG++RVI +EHP L T +DVD+ TD VA+QL S S EDE Sbjct: 1302 NAAVVVAGDAPNLTQAGLRGMMRVIDAEHPHLSATQIDVDDATDPGHVARQLQSRSGEDE 1361 Query: 1385 TAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRVPPGP 1444 TAWR+G WY ARL P PL DRRT V++ DG+R+H+R PGDL+SLEL A DRVPPGP Sbjct: 1362 TAWRDGQWYTARLRPGPLRPADRRTTVVDHGRDGMRLHIRTPGDLESLELTAFDRVPPGP 1421 Query: 1445 GQLEVAVSMSSINFADVLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQIGDRVGG 1504 G++EVAV+ S+INFADVL+AFGR+P + QLG DF H++GDRVGG Sbjct: 1422 GEIEVAVASSTINFADVLVAFGRYPTFEGYQQQLGGDFAGVVTAVGPGVTEHRVGDRVGG 1481 Query: 1505 FSEGGCWRTFLTCDANLAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGDKVLIHS 1564 S GCW +F+ DA AVTLP + + WYGL+DLA I DKVLIHS Sbjct: 1482 LSGNGCWGSFVLADARHAVTLPPEIPLREAAAVPTASATAWYGLHDLARIAPTDKVLIHS 1541 Query: 1565 ATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRDTDGY 1624 TGGVGQAAI+IARA G EIFATAG+P +R +L D+GIEHVYDSRS+EFAEQIRRDTDGY Sbjct: 1542 GTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDMGIEHVYDSRSLEFAEQIRRDTDGY 1601 Query: 1625 GVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLDLALM 1684 GVD+VLNSL GAAQRAG+ELL GGRF+E+GK D+Y ++RLGLFPFRR L+ + +DLAL+ Sbjct: 1602 GVDVVLNSLPGAAQRAGIELLALGGRFIELGKRDIYRDSRLGLFPFRRNLSLFAVDLALL 1661 Query: 1685 SVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDIPRT 1744 + + P VR LL TV+ TA G L P THYPL DA A+R ++ A HTGK+VL +PRT Sbjct: 1662 THSHPHTVRRLLTTVYQRTAAGELPMPRTTHYPLQDAVAAVRLVAAAGHTGKVVLQVPRT 1721 Query: 1745 GSRSVAVPPEQAPVYRRDGSYIITXXXXXXXXFFASKLA----EAGCGRIVLTARSQPNP 1800 S A+PPE+ +R DG+YIIT F A ++A + G GRIVL +RSQP Sbjct: 1722 ASSVAALPPEKVRPFRADGAYIITGGLGGLGLFLAGEMASRDGDVGAGRIVLNSRSQPGE 1781 Query: 1801 KARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN 1860 +AR+ IERL AAGADI VECG+IA+P TA+RLV ATATGLP+RGVLH+AAVVEDATLTN Sbjct: 1782 QARRAIERLRAAGADIAVECGDIAQPDTAERLVTCATATGLPVRGVLHAAAVVEDATLTN 1841 Query: 1861 ITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLF 1920 +TD+LIDR W+PKVYG+WNLH AT GQPL+WFCLFSS AAL+GSPGQGAYAAANSW+D F Sbjct: 1842 VTDDLIDRCWAPKVYGAWNLHQATAGQPLEWFCLFSSAAALVGSPGQGAYAAANSWLDAF 1901 Query: 1921 AHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIP 1980 A WR A+G P +AIAWGAW +VGRAT LAE + ITP EG AFE L+R+DRPY+GY P Sbjct: 1902 ARWRHARGAPATAIAWGAWSQVGRATALAEDAGVAITPTEGFRAFETLLRHDRPYAGYAP 1961 Query: 1981 ILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVI 2040 I+G PWL +RSP+AE F SAGQG KF EL ALP++EW +RRL+ Q S++ Sbjct: 1962 IMGTPWLTSFAQRSPFAEAFRSAGQGRPDAGKFLAELRALPREEWPSAIRRLVSGQLSLL 2021 Query: 2041 LRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAE 2100 LRRTID DR +YGLDSLG LE+RT IE+ETG+R++P AT T R LA++L D LA+ Sbjct: 2022 LRRTIDPDRPLSDYGLDSLGNLELRTRIETETGVRISP---ATITTVRGLAEHLCDELAD 2078 Query: 2101 EEGVAAPAA 2109 AAP A Sbjct: 2079 LP--AAPPA 2085 >tr|Q73YT8|Q73YT8_MYCPA Tax_Id=1770 (pks5)SubName: Full=Pks5;[Mycobacterium paratuberculosis] Length = 2073 Score = 2293 bits (5943), Expect = 0.0 Identities = 1200/2026 (59%), Positives = 1439/2026 (71%), Gaps = 27/2026 (1%) Query: 83 ISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVFTGLTHEDYLVLTTAAGGL 142 + ++ AT++DPQ RLLLETSWEA+E GL +A S T VF GLTH DY +L + Sbjct: 54 LRDQRATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTGVFIGLTHGDYQLLAADTRSV 113 Query: 143 ASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMAVHLACRSLHDGESDLALAG 202 Y +G N S+ASGRI++ LG+HGPA+T DTACSSGL A+HLACRSLH+GESDLALAG Sbjct: 114 EGAYGFSGSNFSLASGRIAYALGVHGPALTVDTACSSGLTAIHLACRSLHEGESDLALAG 173 Query: 203 GCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRI 262 G + L+P A SA+GMLS TGRC++F ADGFV EG M+LLKRL DALRDG+RI Sbjct: 174 GATLALDPRKFSAGSAEGMLSPTGRCRAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRI 233 Query: 263 FAMILGTATNQDGGTETLMMPSEDXXXXXXXXXXXXXXXEPETIGVVEAHGTGTPIGDPI 322 A++ GTA NQDG T + PS+ + T+G+VEAHG GTP+GDPI Sbjct: 234 LAVVRGTAANQDGHTVNIATPSKSAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGDPI 293 Query: 323 EYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAILSLRNGLVPPLLHFDRLSDD 382 EY SLA VYG PCAL S K+N GH+ A++G +G++KAIL+L++G+VP LHF +L DD Sbjct: 294 EYASLAEVYGIDGPCALASVKTNFGHAQAASGALGMMKAILALQHGVVPRNLHFTQLPDD 353 Query: 383 LTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNVHVIVEEAPSEACAPDVPETS 442 L I+T LFVPQ+ TPW G + P+R AVSS+G+SGTNVH I+E+AP A PET Sbjct: 354 LARIDTKLFVPQQTTPWVSNGGH-PRRAAVSSYGLSGTNVHAILEQAPEPA-----PETV 407 Query: 443 PGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDSVVLSDLAYTLARGRAHRPVR 502 + LF LSSTS LR TA +LA WV H D + L DLAYTLAR R HRPVR Sbjct: 408 APEHISAESPLLFPLSSTSADELRRTAGRLADWVHAHDD-LALPDLAYTLARRRVHRPVR 466 Query: 503 TAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVFSGQGSQWASMGVQLLANEPV 562 TAV+A D +L+E L E+ADGD Y A VG GDRGPVWVFSGQGSQWA+MG LLA E V Sbjct: 467 TAVLAGDRAQLIEALREVADGDTPYPAAVGRGDRGPVWVFSGQGSQWAAMGADLLATERV 526 Query: 563 FAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSVFAVQVALATTMEQTYGVRPG 622 FAAT+ + EP+IA ES FSV EA++AP+TVTG D+VQP++F +QVALA TM+ +GVRPG Sbjct: 527 FAATVAQAEPLIARESGFSVAEAMSAPQTVTGQDRVQPTLFTMQVALAATMK-AHGVRPG 585 Query: 623 AVIGHSMXXXXXXXXXXXXXXXDAARVICRRSKLMNRVAGSGAMGSVELPAKQVNSELMA 682 AVIGHS+ D ARVICRRS+LM+RVAG+GA SVELPA+QV SEL A Sbjct: 586 AVIGHSLGEAAAAVVAGALSLEDGARVICRRSRLMSRVAGTGATASVELPAQQVLSELTA 645 Query: 683 RGIDDVVISVVASPQSTVIGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVXXXXXX 742 RGI DVV++VVASPQSTVI GA TVRDL+ W++RDVMAREV DVA HS QV Sbjct: 646 RGISDVVVAVVASPQSTVIAGAAPTVRDLVTAWQERDVMAREVPTDVAFHSPQVDPIMDD 705 Query: 743 XXXXXXXXXXMTPKVPYYSATLFDPRELPVCNGAYWVDNLRNTVQFAAAVQAAMEDGYRV 802 P+VPYYSATLFDPRE PVC+ YW +N+R V+FA AVQAA+EDGYRV Sbjct: 706 LTDALAEISPRPPEVPYYSATLFDPREQPVCDARYWANNMRRMVRFATAVQAALEDGYRV 765 Query: 803 FAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLRGLLADLHSAGAALDFAAL 862 FAEL+PHPLL A+EQTAR+ ++ +AALA MRR Q++P+GLRG +ADLH+AGAA+DF+ L Sbjct: 766 FAELAPHPLLVRALEQTARSREIPMAALASMRRGQALPHGLRGFVADLHNAGAAVDFSVL 825 Query: 863 YPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHPLLGSHVRLLEEPERHIWQGD 922 YP GRL+DAPLP WTH RL++ G E G CTV VHPLLG HV L EEPERH+WQ D Sbjct: 826 YPTGRLVDAPLPTWTHRRLWLTDGGLESPTHGGCTVAVHPLLGPHVHLQEEPERHLWQAD 885 Query: 923 VGTAALSWLADHQVHNVAALPGAAYCEMXXXXXXXXXXXXXXXXXIAFEQMLLLAAETPI 982 VGTAA WLADHQ+ NV LPGAAYCEM I FEQ LLL +T I Sbjct: 886 VGTAAQPWLADHQIRNVVVLPGAAYCEMALAAARSVLGAAAEVRDIRFEQALLLDEQTTI 945 Query: 983 DAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDDCPPPAYDIAALLEAHPNSVNGT 1042 DA ASV +PGV++F VQ++Q GE+ R+A+A L AA D+ P A+D++ALL AHP+ +G Sbjct: 946 DASASVSSPGVLHFTVQSHQGGEQARHASAVLGAAVDE-QPAAHDLSALLAAHPHDDDGA 1004 Query: 1043 DLRESFAERGVQXXXXXXXXXXXXXXXXXSGTVLAEVALPASIRFQQSSYQIHPALLDAC 1102 ++R RGVQ +GTVLAEVALP IR QQ++Y +HPALLDAC Sbjct: 1005 EVRRRMDRRGVQYGPAFAGLGAVHTGDE-TGTVLAEVALPRQIRSQQAAYGVHPALLDAC 1063 Query: 1103 FQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNARYCYTRLTKIEPRGGEADLDVLD 1162 FQSV A +G A L L LG+R LR Y RNA YCYTR+TK + G EAD+DVLD Sbjct: 1064 FQSVEAHPAVRALGDGA-LGLVLGIRRLRAYSAARNAHYCYTRVTKADTSGVEADIDVLD 1122 Query: 1163 EHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQQRTLPESVHVEPGSWLLIDTFN 1222 EHGAVLLAV+GL +GT +E G DR L+ERLL I W+QR LPE H + GSWLLI T Sbjct: 1123 EHGAVLLAVQGLRVGTSASESGTRDRVLAERLLNIEWRQRELPEPEHADAGSWLLIGT-- 1180 Query: 1223 ASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPVVSRERLGRQLRGRD--GVVILC 1280 +A D+ ASTL D LK+ G Q CT ++W Q D V E+L RG GVV+L Sbjct: 1181 -TATADVLASTLADTLKNRGAQ---CTTMAWPQQADHTVHAEQLRNHWRGDGFTGVVVLT 1236 Query: 1281 GPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLFVVTRQAQIVQSGDAANLEQA 1340 GP+ G D++S L +R+ V+HLVRI REL +L GE PRL+VVTR AQ V D NL QA Sbjct: 1237 GPKNGDNDQESALLSRDHVQHLVRIARELTDLPGEPPRLYVVTRNAQTVLPDDVPNLGQA 1296 Query: 1341 GLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGSEEDETAWRNGDWYVARLNPS 1400 GLRGL+RVI EHP L +DVDE TD E +A+QLL+G EEDETAWR+G WY ARL P+ Sbjct: 1297 GLRGLVRVIGMEHPQLGAGQIDVDESTDAEALARQLLAGCEEDETAWRDGAWYTARLCPA 1356 Query: 1401 PLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFAD 1460 PL E+R T V N E DG+R+ +R PGDL+S+ELVA DR+PPGP Q+EVAVS SSINFAD Sbjct: 1357 PLLPEERHTAVANHECDGMRLQIRTPGDLESIELVACDRIPPGPEQIEVAVSASSINFAD 1416 Query: 1461 VLIAFGRFPIIDDRDPQLGMDFXXXXXXXXXXXXXHQIGDRVGGFSEGGCWRTFLTCDAN 1520 VL+AFGR+P + R P+LG DF H++GD VGG S GCW TFLTCDA Sbjct: 1417 VLVAFGRYPAFEGRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWGTFLTCDAR 1476 Query: 1521 LAVTLPSGLTDEQXXXXXXXXXXXWYGLNDLAGIKVGDKVLIHSATGGVGQAAISIARAK 1580 LAVT+P GL D+Q +YGL++LA I GD+VLIHSATGGVGQAAI+IARA Sbjct: 1477 LAVTVPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLIHSATGGVGQAAIAIARAV 1536 Query: 1581 GAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRA 1640 GAEIFATAG+ +R +L D+GIEHVYDSR+VEFA+ IR DTDGYGVDIVLNS+TGAAQRA Sbjct: 1537 GAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFADLIRHDTDGYGVDIVLNSVTGAAQRA 1596 Query: 1641 GLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLDLALMSVTQPDRVRELLATVF 1700 G+ELL FGGRFVEIGK D+YG+TRLGL PFRR LTFY LDLALMS + PDR+R LL TV+ Sbjct: 1597 GIELLAFGGRFVEIGKRDIYGDTRLGLLPFRRNLTFYALDLALMSFSHPDRLRGLLRTVY 1656 Query: 1701 NLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYR 1760 LTADG L PE THYPL DAA+AIR MS A+HTGKLVLD+P G V VPP Q +R Sbjct: 1657 RLTADGALPMPESTHYPLADAASAIRVMSAAQHTGKLVLDVPDAGRSRVVVPPAQVRAFR 1716 Query: 1761 RDGSYIITXXXXXXXXFFASKLA----EAGCGRIVLTARSQPNPKARQTIERLCAAGADI 1816 DG+YI+T F A K+A AGCGRIVL +R+ PNPKA T+ER+ GADI Sbjct: 1717 SDGAYIVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALPNPKALATLERIRQMGADI 1776 Query: 1817 VVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTNITDELIDRDWSPKVYG 1876 VVE G+IAE TA RL++ ATATGLP+RGVLH AAV+EDATL NITDELI+RDW+ KVYG Sbjct: 1777 VVERGDIAEAGTAQRLLDVATATGLPVRGVLHLAAVIEDATLANITDELIERDWAAKVYG 1836 Query: 1877 SWNLHCAT----IGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDLFAHWRRAQGLPVS 1932 +WNLH A Q LDWFC FSS AAL+GSPGQGAYAAANSW+D F WRRA+GL + Sbjct: 1837 AWNLHLALQESGAEQSLDWFCSFSSAAALVGSPGQGAYAAANSWLDAFTRWRRARGLKAT 1896 Query: 1933 AIAWGAWGEVGRATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIPILGAPWLPDLVR 1992 AIAWGAW ++GR LA+ ++ ITPDEGAYAFE L+R+DR +GY PI G PWL + Sbjct: 1897 AIAWGAWAQIGRGAALADSADVAITPDEGAYAFEALLRHDRACTGYAPITGTPWLTAFAQ 1956 Query: 1993 RSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVILRRTIDADRSFI 2052 RSP+AE F + GQ + G SK R EL LP +EWS RLRRL+ +Q S+ILRR +D DR Sbjct: 1957 RSPFAEAFRANGQSATGTSKLRAELEELPPEEWSTRLRRLISDQVSLILRRNVDPDRPLP 2016 Query: 2053 EYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTL 2098 EYGLDSLG LE+ T I++ETGIR++P IA T R LA L D L Sbjct: 2017 EYGLDSLGGLELLTRIQTETGIRVSPADIAAIGTIRGLADLLRDKL 2062 Database: Amellifera_nr Posted date: Jan 15, 2010 5:10 AM Number of letters in database: 3,808,957,724 Number of sequences in database: 11,153,314 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11153314 Number of Hits to DB: 15,020,799,510 Number of extensions: 630593437 Number of successful extensions: 1679592 Number of sequences better than 10.0: 21668 Number of HSP's gapped: 1612424 Number of HSP's successfully gapped: 28465 Length of query: 2116 Length of database: 3,808,957,724 Length adjustment: 153 Effective length of query: 1963 Effective length of database: 2,102,500,682 Effective search space: 4127208838766 Effective search space used: 4127208838766 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 89 (38.9 bits)