BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= ML0226 (191 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,153,314 sequences; 3,808,957,724 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|O69528|HPPK_MYCLE Tax_Id=1769 (folK)RecName: Full=2-amino-4-h... 355 2e-96 tr|B8ZU45|B8ZU45_MYCLB Tax_Id=561304 (folK)SubName: Full=Putativ... 355 2e-96 tr|Q743Y9|Q743Y9_MYCPA Tax_Id=1770 (folK)SubName: Full=FolK;[Myc... 217 6e-55 tr|A5WTH4|A5WTH4_MYCTF Tax_Id=336982 SubName: Full=2-amino-4-hyd... 214 3e-54 tr|A0QA88|A0QA88_MYCA1 Tax_Id=243243 (folK)SubName: Full=2-amino... 213 8e-54 sp|P64143|HPPK_MYCTU Tax_Id=1773 (folK)RecName: Full=2-amino-4-h... 212 2e-53 sp|P64144|HPPK_MYCBO Tax_Id=1765 (folK)RecName: Full=2-amino-4-h... 212 2e-53 tr|C6DMQ7|C6DMQ7_MYCTK Tax_Id=478434 SubName: Full=2-amino-4-hyd... 212 2e-53 tr|A5U8T1|A5U8T1_MYCTA Tax_Id=419947 (folK)SubName: Full=2-amino... 212 2e-53 tr|A4KM82|A4KM82_MYCTU Tax_Id=395095 SubName: Full=2-amino-4-hyd... 212 2e-53 tr|C1AI64|C1AI64_MYCBT Tax_Id=561275 (folK)SubName: Full=2-amino... 211 4e-53 tr|A1KPU1|A1KPU1_MYCBP Tax_Id=410289 (folK)SubName: Full=2-amino... 211 4e-53 tr|A0R584|A0R584_MYCS2 Tax_Id=246196 (folK)SubName: Full=2-amino... 194 4e-48 tr|A3Q6Y9|A3Q6Y9_MYCSJ Tax_Id=164757 SubName: Full=2-amino-4-hyd... 187 4e-46 tr|Q1B2L4|Q1B2L4_MYCSS Tax_Id=164756 SubName: Full=2-amino-4-hyd... 183 7e-45 tr|A1UMI4|A1UMI4_MYCSK Tax_Id=189918 SubName: Full=2-amino-4-hyd... 183 7e-45 tr|B2HJ50|B2HJ50_MYCMM Tax_Id=216594 (folK)SubName: Full=2-amino... 179 2e-43 tr|A0PV54|A0PV54_MYCUA Tax_Id=362242 (folK)SubName: Full=2-amino... 177 5e-43 tr|A4T5N7|A4T5N7_MYCGI Tax_Id=350054 SubName: Full=2-amino-4-hyd... 174 6e-42 tr|A1TG39|A1TG39_MYCVP Tax_Id=350058 SubName: Full=2-amino-4-hyd... 174 6e-42 tr|C1BA71|C1BA71_RHOOB Tax_Id=632772 (folK)SubName: Full=2-amino... 172 2e-41 tr|C0ZPK9|C0ZPK9_RHOE4 Tax_Id=234621 (folK)SubName: Full=2-amino... 171 3e-41 tr|C3JUG7|C3JUG7_RHOER Tax_Id=596309 (folK)SubName: Full=2-amino... 171 3e-41 tr|Q0S8D9|Q0S8D9_RHOSR Tax_Id=101510 SubName: Full=2-amino-4-hyd... 169 2e-40 tr|Q5Z2U7|Q5Z2U7_NOCFA Tax_Id=37329 (folK)SubName: Full=Putative... 164 6e-39 tr|B1MGV2|B1MGV2_MYCA9 Tax_Id=561007 SubName: Full=2-amino-4-hyd... 162 1e-38 tr|C7MQJ0|C7MQJ0_SACVD Tax_Id=471857 SubName: Full=2-amino-4-hyd... 145 2e-33 tr|D0L430|D0L430_9ACTO Tax_Id=526226 SubName: Full=2-amino-4-hyd... 135 3e-30 tr|C6WGH0|C6WGH0_ACTMD Tax_Id=446462 SubName: Full=2-amino-4-hyd... 135 3e-30 tr|A4F6S4|A4F6S4_SACEN Tax_Id=405948 (folK)SubName: Full=2-amino... 132 1e-29 tr|C2ANB2|C2ANB2_TSUPA Tax_Id=521096 SubName: Full=2-amino-4-hyd... 132 2e-29 tr|C0UA20|C0UA20_9ACTO Tax_Id=526225 SubName: Full=2-amino-4-hyd... 129 1e-28 tr|C4RE36|C4RE36_9ACTO Tax_Id=219305 SubName: Full=2-amino-4-hyd... 125 2e-27 tr|C8XA98|C8XA98_NAKMY Tax_Id=479431 SubName: Full=2-amino-4-hyd... 125 2e-27 tr|C4E3D4|C4E3D4_STRRS Tax_Id=479432 SubName: Full=2-amino-4-hyd... 125 2e-27 tr|A4XCR6|A4XCR6_SALTO Tax_Id=369723 SubName: Full=2-amino-4-hyd... 124 7e-27 tr|A8M8G5|A8M8G5_SALAI Tax_Id=391037 SubName: Full=2-amino-4-hyd... 121 3e-26 tr|C4DU23|C4DU23_9ACTO Tax_Id=446470 SubName: Full=2-amino-4-hyd... 121 4e-26 tr|C2BM96|C2BM96_9CORY Tax_Id=525264 SubName: Full=7, 8-dihydro-... 120 7e-26 tr|C0WGS8|C0WGS8_9CORY Tax_Id=525260 SubName: Full=7, 8-dihydro-... 119 1e-25 tr|C6RCA1|C6RCA1_9CORY Tax_Id=553206 (folK)SubName: Full=2-amino... 119 2e-25 tr|C5V8R6|C5V8R6_9CORY Tax_Id=553207 (folK)SubName: Full=2-amino... 117 8e-25 tr|C0E573|C0E573_9CORY Tax_Id=566549 SubName: Full=Putative unch... 117 8e-25 tr|Q8FMG6|Q8FMG6_COREF Tax_Id=152794 SubName: Full=Putative 2-am... 116 1e-24 tr|C8NK06|C8NK06_COREF Tax_Id=196164 (folK)SubName: Full=2-amino... 116 1e-24 tr|Q6NF97|Q6NF97_CORDI Tax_Id=1717 (folK)SubName: Full=Putative ... 114 4e-24 tr|C3PJE5|C3PJE5_CORA7 Tax_Id=548476 (folK)SubName: Full=2-amino... 114 4e-24 tr|C0XP54|C0XP54_9CORY Tax_Id=525263 (folK)SubName: Full=2-amino... 114 4e-24 tr|C2CS34|C2CS34_CORST Tax_Id=525268 (folK)SubName: Full=2-amino... 114 7e-24 tr|Q47KU9|Q47KU9_THEFY Tax_Id=269800 SubName: Full=7, 8-Dihydro-... 113 1e-23 >sp|O69528|HPPK_MYCLE Tax_Id=1769 (folK)RecName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3; AltName: Full=7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Short=HPPK; AltName: Full=6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Short=PPPK;[Mycobacterium leprae] Length = 191 Score = 355 bits (910), Expect = 2e-96 Identities = 179/191 (93%), Positives = 179/191 (93%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLSIGSNLGDRLAWLQS SPVYDTVPWGAVEQRSFLNAVVIADGP Sbjct: 1 MTRVVLSIGSNLGDRLAWLQSAVDGLGDAVVAVSPVYDTVPWGAVEQRSFLNAVVIADGP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL Sbjct: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS Sbjct: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 Query: 181 SPARPVSPKSD 191 SPARPVSPKSD Sbjct: 181 SPARPVSPKSD 191 >tr|B8ZU45|B8ZU45_MYCLB Tax_Id=561304 (folK)SubName: Full=Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase; EC=2.7.6.3;[Mycobacterium leprae] Length = 191 Score = 355 bits (910), Expect = 2e-96 Identities = 179/191 (93%), Positives = 179/191 (93%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLSIGSNLGDRLAWLQS SPVYDTVPWGAVEQRSFLNAVVIADGP Sbjct: 1 MTRVVLSIGSNLGDRLAWLQSAVDGLGDAVVAVSPVYDTVPWGAVEQRSFLNAVVIADGP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL Sbjct: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS Sbjct: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 Query: 181 SPARPVSPKSD 191 SPARPVSPKSD Sbjct: 181 SPARPVSPKSD 191 >tr|Q743Y9|Q743Y9_MYCPA Tax_Id=1770 (folK)SubName: Full=FolK;[Mycobacterium paratuberculosis] Length = 182 Score = 217 bits (552), Expect = 6e-55 Identities = 117/183 (63%), Positives = 132/183 (72%), Gaps = 7/183 (3%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLSIGSNLGDRLA LQS SPVY+T PWG V+Q FLNAV+IAD P Sbjct: 1 MTRVVLSIGSNLGDRLARLQSVVDGLGGAVRAISPVYETQPWGRVDQAPFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A D + WL RAQE ER AGRVRG+RWG RTLDVDLI+CY G EVI+ E+NLTL Sbjct: 61 ACDGQGWLRRAQEFERAAGRVRGERWGPRTLDVDLIACY-------GDGEVISRENNLTL 113 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PWLAVD DA+LTVA Q V RLLA+++ +R+GVR T LTL Sbjct: 114 PHPLAHLRAFVLIPWLAVDPDAQLTVADGPQPVARLLAQLDQADRDGVRPTGLTLTPPAG 173 Query: 181 SPA 183 SPA Sbjct: 174 SPA 176 >tr|A5WTH4|A5WTH4_MYCTF Tax_Id=336982 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK;[Mycobacterium tuberculosis] Length = 188 Score = 214 bits (546), Expect = 3e-54 Identities = 112/182 (61%), Positives = 130/182 (71%), Gaps = 1/182 (0%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLS+GSNLGDRLA L+S SP+Y+ PWG VEQ FLNAV+IAD P Sbjct: 1 MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + + WL RAQE ER AGRVRGQRWG R LDVDLI+CYQTS AT VEV E++LTL Sbjct: 61 TCEPREWLRRAQEFERAAGRVRGQRWGPRNLDVDLIACYQTS-ATEALVEVTARENHLTL 119 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PW+AVD A+LTVAG + V RLLAE+EP +R+ VRL L+ L Sbjct: 120 PHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRLSFDLNSR 179 Query: 181 SP 182 P Sbjct: 180 HP 181 >tr|A0QA88|A0QA88_MYCA1 Tax_Id=243243 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Mycobacterium avium] Length = 182 Score = 213 bits (542), Expect = 8e-54 Identities = 116/183 (63%), Positives = 130/183 (71%), Gaps = 7/183 (3%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLSIGSNLGDRLA LQS SPVY+T PWG V+Q FLNAV+IAD P Sbjct: 1 MTRVVLSIGSNLGDRLARLQSVVDGLGGAVRAISPVYETQPWGRVDQAPFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A D + WL RAQE ER AGRVRG+RWG RTLDVDLI+CY G EVI+ E+NLTL Sbjct: 61 ACDGQGWLRRAQEFERAAGRVRGERWGPRTLDVDLIACY-------GDGEVISRENNLTL 113 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PWLAVD DA LTVA Q V RLLA+++ +R+GVR T LTL Sbjct: 114 PHPLAHLRAFVLIPWLAVDPDARLTVADGPQPVARLLAQLDQADRDGVRPTGLTLTPPAG 173 Query: 181 SPA 183 S A Sbjct: 174 SSA 176 >sp|P64143|HPPK_MYCTU Tax_Id=1773 (folK)RecName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3; AltName: Full=7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Short=HPPK; AltName: Full=6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Short=PPPK;[Mycobacterium tuberculosis] Length = 188 Score = 212 bits (539), Expect = 2e-53 Identities = 111/182 (60%), Positives = 129/182 (70%), Gaps = 1/182 (0%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLS+GSNLGDRLA L+S SP+Y+ PWG VEQ FLNAV+IAD P Sbjct: 1 MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + + WL RAQE ER AGRVRGQRWG R LDVDLI+CYQTS AT VEV E++LTL Sbjct: 61 TCEPREWLRRAQEFERAAGRVRGQRWGPRNLDVDLIACYQTS-ATEALVEVTARENHLTL 119 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PW+AVD A+LTVAG + V RLLAE+EP +R+ VRL + L Sbjct: 120 PHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSR 179 Query: 181 SP 182 P Sbjct: 180 HP 181 >sp|P64144|HPPK_MYCBO Tax_Id=1765 (folK)RecName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3; AltName: Full=7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Short=HPPK; AltName: Full=6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Short=PPPK;[Mycobacterium bovis] Length = 188 Score = 212 bits (539), Expect = 2e-53 Identities = 111/182 (60%), Positives = 129/182 (70%), Gaps = 1/182 (0%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLS+GSNLGDRLA L+S SP+Y+ PWG VEQ FLNAV+IAD P Sbjct: 1 MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + + WL RAQE ER AGRVRGQRWG R LDVDLI+CYQTS AT VEV E++LTL Sbjct: 61 TCEPREWLRRAQEFERAAGRVRGQRWGPRNLDVDLIACYQTS-ATEALVEVTARENHLTL 119 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PW+AVD A+LTVAG + V RLLAE+EP +R+ VRL + L Sbjct: 120 PHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSR 179 Query: 181 SP 182 P Sbjct: 180 HP 181 >tr|C6DMQ7|C6DMQ7_MYCTK Tax_Id=478434 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK;[Mycobacterium tuberculosis] Length = 188 Score = 212 bits (539), Expect = 2e-53 Identities = 111/182 (60%), Positives = 129/182 (70%), Gaps = 1/182 (0%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLS+GSNLGDRLA L+S SP+Y+ PWG VEQ FLNAV+IAD P Sbjct: 1 MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + + WL RAQE ER AGRVRGQRWG R LDVDLI+CYQTS AT VEV E++LTL Sbjct: 61 TCEPREWLRRAQEFERAAGRVRGQRWGPRNLDVDLIACYQTS-ATEALVEVTARENHLTL 119 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PW+AVD A+LTVAG + V RLLAE+EP +R+ VRL + L Sbjct: 120 PHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSR 179 Query: 181 SP 182 P Sbjct: 180 HP 181 >tr|A5U8T1|A5U8T1_MYCTA Tax_Id=419947 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase;[Mycobacterium tuberculosis] Length = 188 Score = 212 bits (539), Expect = 2e-53 Identities = 111/182 (60%), Positives = 129/182 (70%), Gaps = 1/182 (0%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLS+GSNLGDRLA L+S SP+Y+ PWG VEQ FLNAV+IAD P Sbjct: 1 MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + + WL RAQE ER AGRVRGQRWG R LDVDLI+CYQTS AT VEV E++LTL Sbjct: 61 TCEPREWLRRAQEFERAAGRVRGQRWGPRNLDVDLIACYQTS-ATEALVEVTARENHLTL 119 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PW+AVD A+LTVAG + V RLLAE+EP +R+ VRL + L Sbjct: 120 PHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSR 179 Query: 181 SP 182 P Sbjct: 180 HP 181 >tr|A4KM82|A4KM82_MYCTU Tax_Id=395095 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK;[Mycobacterium tuberculosis str. Haarlem] Length = 188 Score = 212 bits (539), Expect = 2e-53 Identities = 111/182 (60%), Positives = 129/182 (70%), Gaps = 1/182 (0%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLS+GSNLGDRLA L+S SP+Y+ PWG VEQ FLNAV+IAD P Sbjct: 1 MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + + WL RAQE ER AGRVRGQRWG R LDVDLI+CYQTS AT VEV E++LTL Sbjct: 61 TCEPREWLRRAQEFERAAGRVRGQRWGPRNLDVDLIACYQTS-ATEALVEVTARENHLTL 119 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PW+AVD A+LTVAG + V RLLAE+EP +R+ VRL + L Sbjct: 120 PHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSR 179 Query: 181 SP 182 P Sbjct: 180 HP 181 >tr|C1AI64|C1AI64_MYCBT Tax_Id=561275 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Mycobacterium bovis] Length = 188 Score = 211 bits (536), Expect = 4e-53 Identities = 110/182 (60%), Positives = 129/182 (70%), Gaps = 1/182 (0%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLS+GSNLGDRLA L+S SP+Y+ PWG VEQ FLNAV+IAD P Sbjct: 1 MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + + WL RA+E ER AGRVRGQRWG R LDVDLI+CYQTS AT VEV E++LTL Sbjct: 61 TCEPREWLRRAEEFERAAGRVRGQRWGPRNLDVDLIACYQTS-ATEALVEVTARENHLTL 119 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PW+AVD A+LTVAG + V RLLAE+EP +R+ VRL + L Sbjct: 120 PHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSR 179 Query: 181 SP 182 P Sbjct: 180 HP 181 >tr|A1KPU1|A1KPU1_MYCBP Tax_Id=410289 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK; EC=2.7.6.3;[Mycobacterium bovis] Length = 188 Score = 211 bits (536), Expect = 4e-53 Identities = 110/182 (60%), Positives = 129/182 (70%), Gaps = 1/182 (0%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLS+GSNLGDRLA L+S SP+Y+ PWG VEQ FLNAV+IAD P Sbjct: 1 MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + + WL RA+E ER AGRVRGQRWG R LDVDLI+CYQTS AT VEV E++LTL Sbjct: 61 TCEPREWLRRAEEFERAAGRVRGQRWGPRNLDVDLIACYQTS-ATEALVEVTARENHLTL 119 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PW+AVD A+LTVAG + V RLLAE+EP +R+ VRL + L Sbjct: 120 PHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSR 179 Query: 181 SP 182 P Sbjct: 180 HP 181 >tr|A0R584|A0R584_MYCS2 Tax_Id=246196 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Mycobacterium smegmatis] Length = 178 Score = 194 bits (493), Expect = 4e-48 Identities = 104/183 (56%), Positives = 124/183 (67%), Gaps = 6/183 (3%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MT VLSIGSNLGDRL LQS S VY+T WG EQ FLNAV++AD P Sbjct: 1 MTSTVLSIGSNLGDRLTRLQSVLDGLGPAVRAVSAVYETAAWGFEEQGPFLNAVLLADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D WL RAQELE AGRVRGQRWG RTLDVDLI+C+ GA E+I+ + LTL Sbjct: 61 DLDGHGWLRRAQELEAAAGRVRGQRWGPRTLDVDLITCHD------GADEIISRDEGLTL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKLKRS 180 PHP AHLRAFVL+PWL VD DA LTVAG ++ V RLL+E++ +ER+GV T+L L ++ Sbjct: 115 PHPLAHLRAFVLIPWLDVDPDATLTVAGESRPVQRLLSEIDQSERDGVTRTDLVLDIRTE 174 Query: 181 SPA 183 + A Sbjct: 175 TAA 177 >tr|A3Q6Y9|A3Q6Y9_MYCSJ Tax_Id=164757 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3; Flags: Precursor;[Mycobacterium sp.] Length = 176 Score = 187 bits (476), Expect = 4e-46 Identities = 98/176 (55%), Positives = 119/176 (67%), Gaps = 6/176 (3%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MT+VVLSIGSN+GDRLA LQS SPVY+T WG VEQ +FLNAV+IAD P Sbjct: 1 MTKVVLSIGSNVGDRLARLQSVVDGLGEAVRAVSPVYETAAWGGVEQGAFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D WL R Q+LE+ A RVRGQRWG RTLDVD+++C+ G EV + + LTL Sbjct: 61 DLDCHGWLRRGQQLEQEADRVRGQRWGPRTLDVDIVTCHD------GDTEVRSATAELTL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLK 176 PHP AHLRAFVL+PWLA + +A LTVA + V L E++P ER GVR T+L L+ Sbjct: 115 PHPYAHLRAFVLMPWLAAEPEATLTVADTTRPVSLWLEELDPAERAGVRRTDLALR 170 >tr|Q1B2L4|Q1B2L4_MYCSS Tax_Id=164756 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3; Flags: Precursor;[Mycobacterium sp.] Length = 176 Score = 183 bits (465), Expect = 7e-45 Identities = 97/176 (55%), Positives = 117/176 (66%), Gaps = 6/176 (3%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLSIGSN+GDRLA LQS SPVY+T WG VEQ +FLNAV+IAD P Sbjct: 1 MTRVVLSIGSNVGDRLARLQSVVDGLGEAVRAVSPVYETAAWGGVEQGAFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D WL R Q+LE+ A RVRGQRWG RTLDVD+++C+ G EV + + LTL Sbjct: 61 DLDCHGWLRRGQQLEQEADRVRGQRWGPRTLDVDIVTCHD------GDTEVRSATAELTL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLK 176 PHP AHLR FVL+PWLA + +A LTVA + V L E++ ER GVR T+L L+ Sbjct: 115 PHPYAHLRGFVLMPWLAAEPEATLTVADTTRPVSLWLEELDYAERAGVRRTDLALR 170 >tr|A1UMI4|A1UMI4_MYCSK Tax_Id=189918 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3; Flags: Precursor;[Mycobacterium sp.] Length = 176 Score = 183 bits (465), Expect = 7e-45 Identities = 97/176 (55%), Positives = 117/176 (66%), Gaps = 6/176 (3%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTRVVLSIGSN+GDRLA LQS SPVY+T WG VEQ +FLNAV+IAD P Sbjct: 1 MTRVVLSIGSNVGDRLARLQSVVDGLGEAVRAVSPVYETAAWGGVEQGAFLNAVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D WL R Q+LE+ A RVRGQRWG RTLDVD+++C+ G EV + + LTL Sbjct: 61 DLDCHGWLRRGQQLEQEADRVRGQRWGPRTLDVDIVTCHD------GDTEVRSATAELTL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLK 176 PHP AHLR FVL+PWLA + +A LTVA + V L E++ ER GVR T+L L+ Sbjct: 115 PHPYAHLRGFVLMPWLAAEPEATLTVADTTRPVSLWLEELDYAERAGVRRTDLALR 170 >tr|B2HJ50|B2HJ50_MYCMM Tax_Id=216594 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK;[Mycobacterium marinum] Length = 175 Score = 179 bits (453), Expect = 2e-43 Identities = 100/175 (57%), Positives = 115/175 (65%), Gaps = 2/175 (1%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+ VVLS+GSNLGDRLA L+S S VY+T PWG V Q FLN V+IAD P Sbjct: 1 MSSVVLSVGSNLGDRLANLRSVVDGLGDTLVGASRVYETDPWGGVAQEPFLNVVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A D AWL +AQE ER AGR R QRWG RTLDVDL++CYQ A G EV +S LTL Sbjct: 61 ARDGHAWLHQAQEFERAAGRQRLQRWGPRTLDVDLVACYQAGPA--GRTEVRCNDSILTL 118 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTL 175 PHP AH RAFV+VPWL VD AELT + V LLA + P +R VRLT+LT+ Sbjct: 119 PHPLAHQRAFVMVPWLDVDPAAELTAPEGPRPVAALLAGLPPADRASVRLTSLTV 173 >tr|A0PV54|A0PV54_MYCUA Tax_Id=362242 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK;[Mycobacterium ulcerans] Length = 175 Score = 177 bits (449), Expect = 5e-43 Identities = 100/175 (57%), Positives = 115/175 (65%), Gaps = 2/175 (1%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+ VVLS+GSNLGDRLA L+S S VY+T PWG V Q FLN V+IAD P Sbjct: 1 MSSVVLSVGSNLGDRLANLRSVVDGLGDTLVGASRVYETDPWGGVAQEPFLNVVLIADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A D AWL +AQE ER AGR R QRWG RTLDVDL++CYQ A G EV +S LTL Sbjct: 61 ARDGHAWLHQAQEYERAAGRQRLQRWGPRTLDVDLVACYQAGPA--GRTEVRCNDSILTL 118 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTL 175 PHP AH RAFV+VPWL VD AELT + V LLA + P +R VRLT+LT+ Sbjct: 119 PHPLAHQRAFVMVPWLDVDPAAELTGPEGPRPVAALLAGLPPADRASVRLTSLTV 173 >tr|A4T5N7|A4T5N7_MYCGI Tax_Id=350054 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Mycobacterium gilvum] Length = 168 Score = 174 bits (440), Expect = 6e-42 Identities = 96/176 (54%), Positives = 111/176 (63%), Gaps = 13/176 (7%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MT VVLSIGSNLGDRLA LQS SPVY+T WG VEQ FLNA+V+A+ P Sbjct: 1 MTSVVLSIGSNLGDRLAHLQSVLDALGPAVTGVSPVYETDAWGGVEQGPFLNAIVLAEDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A D WL RA ELE GR R Q WG RTLDVDL+SC G E++ + +LTL Sbjct: 61 ALDAHGWLRRAHELEDACGRTREQHWGPRTLDVDLVSC------RDGDAEIVMDDPDLTL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLK 176 PHP AH+RAFVLVPW AVD+ A A V LA ++P ER GVRLT+L L+ Sbjct: 115 PHPYAHVRAFVLVPWSAVDASA-------ASAVSAHLAALDPAERAGVRLTDLVLR 163 >tr|A1TG39|A1TG39_MYCVP Tax_Id=350058 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Mycobacterium vanbaalenii] Length = 175 Score = 174 bits (440), Expect = 6e-42 Identities = 96/177 (54%), Positives = 111/177 (62%), Gaps = 6/177 (3%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MT VVLSIGSNLGDR+A LQS SPVY+T WG VEQ FLNAVV+A+ Sbjct: 1 MTSVVLSIGSNLGDRMAHLQSVLDGLAGSALAVSPVYETDAWGGVEQGPFLNAVVLAEDR 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D WL RA ELE AGRVR QRWG RTLDVDL+ C+ G EV+ + LTL Sbjct: 61 ELDGYGWLRRAHELEDAAGRVRDQRWGPRTLDVDLVQCHGPDG------EVVVHDDVLTL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKL 177 PHP AH RAFVLVPWL V+ A LTV GR + LA ++ ER GVR T+ L++ Sbjct: 115 PHPYAHARAFVLVPWLQVEPTATLTVDGRTDPLTAHLAAVDAAERAGVRTTDFVLRI 171 >tr|C1BA71|C1BA71_RHOOB Tax_Id=632772 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Rhodococcus opacus] Length = 170 Score = 172 bits (436), Expect = 2e-41 Identities = 95/175 (54%), Positives = 110/175 (62%), Gaps = 10/175 (5%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+R VLSIGSN+GD LA LQS SPVY T PWG VEQ+ FLNAVV+AD P Sbjct: 1 MSRAVLSIGSNVGDSLAHLQSVLDGLGDAVVAVSPVYSTAPWGGVEQQDFLNAVVVADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A D WL R QELE A RVR +RWG RTLDVD+++C +V + + LTL Sbjct: 61 ALDGWGWLRRGQELEAAADRVRVERWGPRTLDVDVVTC----------DDVRSDDPELTL 110 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTL 175 PHPRAH RAFVL+PWL V+ DA L V G RVD LL ++ ER GV T L L Sbjct: 111 PHPRAHERAFVLIPWLDVEPDAVLPVDGTTTRVDVLLPLLDDEERAGVHRTGLAL 165 >tr|C0ZPK9|C0ZPK9_RHOE4 Tax_Id=234621 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Rhodococcus erythropolis] Length = 167 Score = 171 bits (434), Expect = 3e-41 Identities = 92/175 (52%), Positives = 111/175 (63%), Gaps = 10/175 (5%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTR VLSIGSN+GD +A LQS SPVY T PWG VEQ+ F NAVV+ D P Sbjct: 1 MTRAVLSIGSNIGDSVAHLQSVVDGLGSAVVAVSPVYSTAPWGGVEQQDFYNAVVVVDDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D WL R+Q LE A RVR QRWG R+LDVD++ C V++ + LTL Sbjct: 61 EADAAEWLRRSQALEEAADRVREQRWGPRSLDVDVVDC----------EGVVSSDPVLTL 110 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTL 175 PHPRAHLRAFVLVPWL V+ DA L V G+ V ++L ++ TEREGVR T++ L Sbjct: 111 PHPRAHLRAFVLVPWLDVEPDATLIVDGQKLPVAQILDGLDRTEREGVRTTDVVL 165 >tr|C3JUG7|C3JUG7_RHOER Tax_Id=596309 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Rhodococcus erythropolis SK121] Length = 167 Score = 171 bits (434), Expect = 3e-41 Identities = 92/175 (52%), Positives = 111/175 (63%), Gaps = 10/175 (5%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTR VLSIGSN+GD +A LQS SPVY T PWG VEQ+ F NAVV+ D P Sbjct: 1 MTRAVLSIGSNIGDSVAHLQSVVDGLGSAVVAVSPVYSTAPWGGVEQQDFYNAVVVVDDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D WL R+Q LE A RVR QRWG R+LDVD++ C V++ + LTL Sbjct: 61 EADAAEWLRRSQALEEAADRVREQRWGPRSLDVDVVDC----------EGVVSSDPVLTL 110 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTL 175 PHPRAHLRAFVLVPWL V+ DA L V G+ V ++L ++ TEREGVR T++ L Sbjct: 111 PHPRAHLRAFVLVPWLDVEPDATLIVDGQKLPVAQILDGLDRTEREGVRTTDVVL 165 >tr|Q0S8D9|Q0S8D9_RHOSR Tax_Id=101510 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; EC=2.7.6.3;[Rhodococcus sp.] Length = 170 Score = 169 bits (427), Expect = 2e-40 Identities = 92/175 (52%), Positives = 109/175 (62%), Gaps = 10/175 (5%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+R VLSIGSN+GD LA LQS SPVY T PWG VEQ+ FLNAV++ D P Sbjct: 1 MSRAVLSIGSNVGDSLAHLQSVLDGLGDAVVAVSPVYSTAPWGGVEQQDFLNAVLVVDDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A D WL R QELE A RVR +RWG RTLDVD+++C +V + + LTL Sbjct: 61 ALDGYGWLRRGQELEAAADRVRIERWGPRTLDVDVVTC----------DDVRSDDPELTL 110 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTL 175 PHPRAH RAFVL+PWL V+ +A L V G RVD LL ++ ER GV T L L Sbjct: 111 PHPRAHERAFVLIPWLDVEPEAVLRVDGTTTRVDALLPLLDDDERAGVHRTQLVL 165 >tr|Q5Z2U7|Q5Z2U7_NOCFA Tax_Id=37329 (folK)SubName: Full=Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase;[Nocardia farcinica] Length = 181 Score = 164 bits (414), Expect = 6e-39 Identities = 86/176 (48%), Positives = 107/176 (60%), Gaps = 6/176 (3%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+R VLSIGSNLGDRL +L+S S VY T PWG VEQ FLNA+++ D P Sbjct: 1 MSRAVLSIGSNLGDRLGYLRSVVDAVADRLVAVSSVYTTAPWGGVEQDDFLNAILVVDDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + WL Q LER A R R RWGARTLDVD+I C G V++ + LT+ Sbjct: 61 DRGCRDWLALGQRLERAAHRTRAVRWGARTLDVDVIWCADADG------PVVSADPELTV 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLK 176 PHPRAH RAFVL+PWL + A L V + V LA ++P ER+GVR T+L+L+ Sbjct: 115 PHPRAHERAFVLIPWLEAEPHARLAVGDVERSVRDWLAALDPAERDGVRRTDLSLR 170 >tr|B1MGV2|B1MGV2_MYCA9 Tax_Id=561007 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (FolK);[Mycobacterium abscessus] Length = 172 Score = 162 bits (411), Expect = 1e-38 Identities = 91/173 (52%), Positives = 112/173 (64%), Gaps = 7/173 (4%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+GDRLA LQS SPVY T PWG V Q F NA+V+ADG Sbjct: 2 RAVLSIGSNVGDRLAHLQSVVDALGSDVVGVSPVYQTAPWGHVPQPDFFNAIVVADGR-- 59 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 + WL A LE++A R+R +RWG RTLDVD+ISC + A EV++ + +LTLPH Sbjct: 60 EPLEWLAVAHRLEQSAQRLRDERWGPRTLDVDVISCRRHD-----AGEVLSDDPDLTLPH 114 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTL 175 PRAHLRAFVLVPWLA++ A LTV G + V LL+ ++ EREGVR + L Sbjct: 115 PRAHLRAFVLVPWLALEPGAVLTVDGVVRPVADLLSGLDAAEREGVRRMDAAL 167 >tr|C7MQJ0|C7MQJ0_SACVD Tax_Id=471857 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase;[Saccharomonospora viridis] Length = 163 Score = 145 bits (366), Expect = 2e-33 Identities = 85/170 (50%), Positives = 104/170 (61%), Gaps = 13/170 (7%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+R VLS+GSNLGDR+ +L+ S VY+T PWG +Q FLNAV I D P Sbjct: 1 MSRAVLSLGSNLGDRVGYLRLAVDGLRDVLVAVSSVYETKPWGVTDQPDFLNAVCIVDDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A D AWL AQELER A RVR +RWG RTLDVD++ T AV + + L L Sbjct: 61 ARDHWAWLRTAQELERRAQRVRERRWGPRTLDVDVV--------TVDAVR--SDDPELLL 110 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRL 170 PHP AH R+ VL+PWL +D DAE V GR + D LLA ++ +R GVRL Sbjct: 111 PHPGAHERSTVLIPWLEIDPDAE--VPGRGRAAD-LLAALDEDDRAGVRL 157 >tr|D0L430|D0L430_9ACTO Tax_Id=526226 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; EC=2.7.6.3;[Gordonia bronchialis DSM 43247] Length = 171 Score = 135 bits (339), Expect = 3e-30 Identities = 81/169 (47%), Positives = 93/169 (55%), Gaps = 7/169 (4%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTR VLS GSN+GDR A L S S VY T PWG VEQ F N +I DGP Sbjct: 1 MTRAVLSAGSNIGDRNAHLASVVSGFADELIAVSHVYATPPWGGVEQDDFHNITLIVDGP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + WL R LER A RVR RWG RTLDVD+IS G VI+ + +LTL Sbjct: 61 LTPAQ-WLARGLRLERAADRVREVRWGPRTLDVDVISVIGPDG------PVISDDPDLTL 113 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVR 169 PHPRA RAFVL+PWL +D DA L V L+ ++ ER VR Sbjct: 114 PHPRAAERAFVLIPWLEIDPDATLWTPAGEIPVAELVERLDDAERRDVR 162 >tr|C6WGH0|C6WGH0_ACTMD Tax_Id=446462 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; EC=2.7.6.3;[Actinosynnema mirum] Length = 158 Score = 135 bits (339), Expect = 3e-30 Identities = 78/150 (52%), Positives = 91/150 (60%), Gaps = 13/150 (8%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+R VLS+GSNLGDRLA L+S SPVY+T PWG +Q FLNAV++ +G Sbjct: 1 MSRAVLSLGSNLGDRLAHLRSAVDGFRPWLLAASPVYETAPWGVTDQDDFLNAVLLVEGD 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCES-NLT 119 D WL R QELER AGRVR +RWG RTLDVD++ AV+ + E L Sbjct: 61 -LDEWGWLRRGQELERAAGRVRERRWGPRTLDVDVV-----------AVDDVRSEDPELL 108 Query: 120 LPHPRAHLRAFVLVPWLAVDSDAELTVAGR 149 LPHP AH RA VL PWL VD DA L GR Sbjct: 109 LPHPGAHERATVLAPWLDVDPDAVLPGHGR 138 >tr|A4F6S4|A4F6S4_SACEN Tax_Id=405948 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Saccharopolyspora erythraea] Length = 167 Score = 132 bits (333), Expect = 1e-29 Identities = 76/170 (44%), Positives = 97/170 (57%), Gaps = 13/170 (7%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+R VLS+GSNLGDRLA L+ SPVY+T PWG +Q FLNAV++ + Sbjct: 1 MSRAVLSLGSNLGDRLAHLRLAVEGFSDVLVAASPVYETAPWGVTDQPDFLNAVIVVESA 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D WL R QELER A RVR +RWG RTLDVD++S +V + + L L Sbjct: 61 GVDEWGWLRRGQELERAAERVRERRWGPRTLDVDVVS----------VDDVRSDDPELLL 110 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRL 170 PHP RA VL+PW ++D +A+L G + LLA + E GVRL Sbjct: 111 PHPGTPSRATVLIPWHSIDPEAQLPGRG---PIAALLAALPEDEVSGVRL 157 >tr|C2ANB2|C2ANB2_TSUPA Tax_Id=521096 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase;[Tsukamurella paurometabola DSM 20162] Length = 162 Score = 132 bits (332), Expect = 2e-29 Identities = 77/164 (46%), Positives = 94/164 (57%), Gaps = 9/164 (5%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTR VLSIG+NLGD ++ SP+Y T PWG VEQ F+NA V+AD P Sbjct: 1 MTRAVLSIGANLGDAETAVRGAITALGPALVAASPLYRTPPWGGVEQDDFINATVLADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 + WL A++ E A R+R RWG RTLDVD+I+ + V + + + LTL Sbjct: 61 SRTAAGWLDFARDQEAAADRIRDVRWGPRTLDVDVIAVWDAE------VPIRSDDPELTL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTE 164 PHPRAH RAFVLVPW AVD AEL G VD LLA + E Sbjct: 115 PHPRAHQRAFVLVPWRAVDPAAELPGHG---TVDDLLAALPAGE 155 >tr|C0UA20|C0UA20_9ACTO Tax_Id=526225 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase;[Geodermatophilus obscurus DSM 43160] Length = 168 Score = 129 bits (325), Expect = 1e-28 Identities = 78/166 (46%), Positives = 97/166 (58%), Gaps = 11/166 (6%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXX--SPVYDTVPWGAVEQRSFLNAVVIAD 58 MTR VLS+G+NLGDR A L++ S +Y+ PWG VEQ +LNAVV+ Sbjct: 1 MTRAVLSLGANLGDRAAALRTAVTTLKDDGVLVARSTLYEAPPWGPVEQPPYLNAVVVVR 60 Query: 59 GPAYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNL 118 G D WL RA ELE+ AGR R RWG RTLDVD+++ G V++ + L Sbjct: 61 GDR-DAAGWLARAHELEQAAGRSRDVRWGPRTLDVDVVTATGDDGQ-----PVLSDDPAL 114 Query: 119 TLPHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTE 164 TLPHPRAH RAFVLVPW ++D A L G RV LLA + P + Sbjct: 115 TLPHPRAHERAFVLVPWASLDPTAVLPGRG---RVSDLLAALPPED 157 >tr|C4RE36|C4RE36_9ACTO Tax_Id=219305 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; Flags: Fragment;[Micromonospora sp. ATCC 39149] Length = 324 Score = 125 bits (315), Expect = 2e-27 Identities = 72/161 (44%), Positives = 98/161 (60%), Gaps = 9/161 (5%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 ++R +LS+GSNLGDRLA L++ S VY+T PWG V+Q ++LNAVV+ + P Sbjct: 150 VSRALLSLGSNLGDRLAHLRTAVDSLGDAVLLCSGVYETPPWGDVDQPAYLNAVVLVEDP 209 Query: 61 AYDTKAWLCRAQELERNAGRVRG--QRWGARTLDVDLISCYQTSGATTGAVEVITCESNL 118 A + WL RA+ ER AGR R +R+G RTLDVD+++ + +G V++ + L Sbjct: 210 AATPRDWLERARAAERRAGRERDPQRRFGPRTLDVDVVAAWDDAGE-----PVLSDDPEL 264 Query: 119 TLPHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAE 159 TLPHPRAHLRAFVL PW+ + L G D L AE Sbjct: 265 TLPHPRAHLRAFVLRPWIDIQPYGRL--PGHGWLTDLLSAE 303 >tr|C8XA98|C8XA98_NAKMY Tax_Id=479431 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; EC=2.7.6.3;[Nakamurella multipartita] Length = 163 Score = 125 bits (314), Expect = 2e-27 Identities = 76/157 (48%), Positives = 88/157 (56%), Gaps = 7/157 (4%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M+R VLS+GSN+GDR A LQ+ S +Y T PWG V Q + N VVIA+ Sbjct: 1 MSRAVLSLGSNVGDRTAHLQTAVNSLGRTVRAVSSIYRTPPWGGVPQPDYYNLVVIAEDD 60 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 D AW R Q LE+ AGR R RWG RTLD D+I A VI+ E LTL Sbjct: 61 GNDAHAWWERCQALEQEAGRERTIRWGPRTLDADVIVVEVHGHA------VISDEPELTL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGR-AQRVDRL 156 PHPRA RAFVL PW +D AEL AG A +DRL Sbjct: 115 PHPRAAQRAFVLRPWAEIDPTAELPGAGAIADLLDRL 151 >tr|C4E3D4|C4E3D4_STRRS Tax_Id=479432 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Streptosporangium roseum DSM 43021] Length = 165 Score = 125 bits (314), Expect = 2e-27 Identities = 86/179 (48%), Positives = 108/179 (60%), Gaps = 23/179 (12%) Query: 3 RVVLSIGSNLGDRLAWLQ----SXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIAD 58 +VVL++GSNLGDR LQ S SPVY+T P+G EQ +LNAVVIA Sbjct: 2 KVVLALGSNLGDRFDTLQGALDSLFDAPGLEFVAVSPVYETDPFGGPEQGPYLNAVVIAH 61 Query: 59 GPAYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNL 118 + + L RAQ +E GRVR +RWGARTLDVDLI T G +V++ + L Sbjct: 62 S-TLEPRTLLDRAQGVENAFGRVRAERWGARTLDVDLI--------TVG--DVVSDDPEL 110 Query: 119 TLPHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRL-TNLTLK 176 TLPHPRAH RAFVLVPW D DA L+ +RVD LLA + +++ VRL +LTL+ Sbjct: 111 TLPHPRAHERAFVLVPWSRADPDAVLS----GRRVDDLLAAL---DQDYVRLRADLTLQ 162 >tr|A4XCR6|A4XCR6_SALTO Tax_Id=369723 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Salinispora tropica] Length = 175 Score = 124 bits (310), Expect = 7e-27 Identities = 69/138 (50%), Positives = 86/138 (62%), Gaps = 7/138 (5%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTR +LS+GSNLGDR+ L+S S VY+T PWG +Q ++LNA V+AD P Sbjct: 1 MTRALLSLGSNLGDRVDHLRSVVTALGESVLLVSGVYETPPWGDRDQPAYLNAAVLADDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVR--GQRWGARTLDVDLISCYQTSGATTGAVEVITCESNL 118 + WL RAQ ER AGR R +R+G RTLDVD+I+ + G V+ + L Sbjct: 61 EAAPEDWLARAQAAERAAGRERDPARRFGPRTLDVDIIAVWTQDG-----TPVLRDDPEL 115 Query: 119 TLPHPRAHLRAFVLVPWL 136 TLPHPRAHLRAFVL PWL Sbjct: 116 TLPHPRAHLRAFVLRPWL 133 >tr|A8M8G5|A8M8G5_SALAI Tax_Id=391037 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase;[Salinispora arenicola] Length = 175 Score = 121 bits (304), Expect = 3e-26 Identities = 67/140 (47%), Positives = 87/140 (62%), Gaps = 7/140 (5%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MTR +LS+GSNLGDR L+S S VY+T PWG +Q ++LNAVV+A+ P Sbjct: 1 MTRALLSLGSNLGDRAGHLRSAVASLGGSVLLVSGVYETPPWGDSDQPAYLNAVVLAEDP 60 Query: 61 AYDTKAWLCRAQELERNAGRVR--GQRWGARTLDVDLISCYQTSGATTGAVEVITCESNL 118 + + WL RA+ ER AGR R +R+G RTLDVD+I + G ++ + L Sbjct: 61 DAEPEDWLARARAAERAAGRERDPARRFGPRTLDVDVIVVWTQEG-----TPMLRDDPEL 115 Query: 119 TLPHPRAHLRAFVLVPWLAV 138 TLPHPRAHLRAFVL PWL + Sbjct: 116 TLPHPRAHLRAFVLRPWLDI 135 >tr|C4DU23|C4DU23_9ACTO Tax_Id=446470 SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase;[Stackebrandtia nassauensis DSM 44728] Length = 169 Score = 121 bits (303), Expect = 4e-26 Identities = 77/173 (44%), Positives = 99/173 (57%), Gaps = 14/173 (8%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 MT VVLS+G+NLGDR A L S S VY+T PWG +Q ++LN +IA Sbjct: 1 MTTVVLSLGANLGDRRAALASAAEALGPGQL--SEVYETPPWGDDDQPTYLNLAMIATDA 58 Query: 61 AYDTKAWLCRAQELERNAGRVRG--QRWGARTLDVDLISCYQTSGATTGAVEVITCES-N 117 + WL A++++ AGRVR +R+G R LDVD+I + G E I C+S Sbjct: 59 DRSVEDWLALAEDIQAKAGRVRDPKRRYGPRVLDVDIIMAWDADG------EPIHCDSPT 112 Query: 118 LTLPHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDR---LLAEMEPTEREG 167 LTLPHPRAHLRAFVLVPWL++ DA L GR + + R L A+ R G Sbjct: 113 LTLPHPRAHLRAFVLVPWLSLQPDAALPGRGRLRDLLRDPGLAADARALRRVG 165 >tr|C2BM96|C2BM96_9CORY Tax_Id=525264 SubName: Full=7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; EC=2.7.6.3;[Corynebacterium pseudogenitalium ATCC 33035] Length = 161 Score = 120 bits (301), Expect = 7e-26 Identities = 75/167 (44%), Positives = 95/167 (56%), Gaps = 15/167 (8%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+ DR+ L++ SPVY T PWG +Q FLNAV+I D Sbjct: 2 RAVLSIGSNMDDRVELLRTVFDEFAGEIVAASPVYATPPWGVTDQDEFLNAVLIVD-VEE 60 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 K L R Q+LE A RVR + WG RTLDVD++ G T+ E+I +PH Sbjct: 61 TPKELLRRGQKLEEAAERVRVRHWGPRTLDVDIV---DIEGYTSDDPELI-------VPH 110 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVR 169 P AH RAFVL+PWLA D+ A L+ G A+RV A ++P ER +R Sbjct: 111 PYAHERAFVLIPWLAADAGARLSGEGVAKRV----AALDPQERADIR 153 >tr|C0WGS8|C0WGS8_9CORY Tax_Id=525260 SubName: Full=7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; EC=2.7.6.3;[Corynebacterium accolens ATCC 49725] Length = 161 Score = 119 bits (299), Expect = 1e-25 Identities = 73/175 (41%), Positives = 96/175 (54%), Gaps = 15/175 (8%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+ DR+ L++ SPVY T PWG +Q FLNAV+I D Sbjct: 2 RAVLSIGSNMDDRVELLRTVFTEFREDIVAASPVYSTPPWGVTDQDEFLNAVLIVDVQES 61 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 + L R Q+LE A RVR + WG RTLDVD++ S A ++ LT+PH Sbjct: 62 PLEL-LRRGQKLEEAAERVRVRHWGPRTLDVDIVDIEGYSSA----------DAELTVPH 110 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRLTNLTLKL 177 P AH RAFVL+PWLA D+ A+L + Q V L+A ++P E + L +L Sbjct: 111 PYAHERAFVLIPWLAADAAAKL----KGQDVSALVAALDPQETADIHRLGLMEEL 161 >tr|C6RCA1|C6RCA1_9CORY Tax_Id=553206 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; EC=2.7.6.3;[Corynebacterium tuberculostearicum SK141] Length = 161 Score = 119 bits (297), Expect = 2e-25 Identities = 75/168 (44%), Positives = 93/168 (55%), Gaps = 17/168 (10%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+ DR+ L++ SPVY T PWG +Q FLNAV+I D Sbjct: 2 RAVLSIGSNMDDRVELLRTVFDEFAGEIVAASPVYATPPWGVTDQDEFLNAVLIVDVDE- 60 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCES-NLTLP 121 K L R Q+LE A RVR + WG RTLDVD+I +E T E L +P Sbjct: 61 TPKELLRRGQKLEEAAERVRVRHWGPRTLDVDIID-----------IEGYTSEDPELIVP 109 Query: 122 HPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVR 169 HP H RAFVL+PWLA D+ A L+ G A+RV A ++P ER +R Sbjct: 110 HPYGHERAFVLIPWLAADAGARLSGEGVAKRV----AALDPKERAEIR 153 >tr|C5V8R6|C5V8R6_9CORY Tax_Id=553207 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; EC=2.7.6.3;[Corynebacterium matruchotii ATCC 14266] Length = 161 Score = 117 bits (292), Expect = 8e-25 Identities = 70/162 (43%), Positives = 94/162 (58%), Gaps = 7/162 (4%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M R VLSIGSN+ DR A L++ SP+Y T PWG +Q FLNA++I + Sbjct: 1 MIRAVLSIGSNMDDRYALLETVFEEFRDETIAQSPIYSTPPWGVPDQDEFLNAILIVN-V 59 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A + L R Q LE A R R ++WG RTLDVD+I +G VE+++ + L L Sbjct: 60 AQTPRELLRRGQHLEAAAERRRTRKWGPRTLDVDIIQVIDANG-----VELVSEDPELIL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRL-LAEME 161 PHP A RAFVLVPWLA D +A L + V++L +A++E Sbjct: 115 PHPWARHRAFVLVPWLAADPEARLLGVPVREIVEKLDIADVE 156 >tr|C0E573|C0E573_9CORY Tax_Id=566549 SubName: Full=Putative uncharacterized protein;[Corynebacterium matruchotii ATCC 33806] Length = 161 Score = 117 bits (292), Expect = 8e-25 Identities = 70/162 (43%), Positives = 94/162 (58%), Gaps = 7/162 (4%) Query: 1 MTRVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGP 60 M R VLSIGSN+ DR A L++ SP+Y T PWG +Q FLNA++I + Sbjct: 1 MIRAVLSIGSNMDDRYALLETVFEEFRDETIAQSPIYSTPPWGVPDQDEFLNAILIVN-V 59 Query: 61 AYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTL 120 A + L R Q LE A R R ++WG RTLDVD+I +G VE+++ + L L Sbjct: 60 AQTPRELLRRGQRLEAAAERRRTRKWGPRTLDVDIIQVIDANG-----VELVSEDPELIL 114 Query: 121 PHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRL-LAEME 161 PHP A RAFVLVPWLA D +A L + V++L +A++E Sbjct: 115 PHPWARHRAFVLVPWLAADPEARLLGVPVREIVEKLDIADVE 156 >tr|Q8FMG6|Q8FMG6_COREF Tax_Id=152794 SubName: Full=Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase;[Corynebacterium efficiens] Length = 162 Score = 116 bits (291), Expect = 1e-24 Identities = 70/166 (42%), Positives = 93/166 (56%), Gaps = 11/166 (6%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+ DR A LQ S +Y T PWG +Q FLNAV++ D Sbjct: 2 RAVLSIGSNMDDRYALLQGVIDEFRDNLVAVSSIYATPPWGVEDQDEFLNAVLVVDVDGI 61 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 + L R Q+LE +A RVR ++WG RTLDVD++ G E+++ + LTLPH Sbjct: 62 PIEL-LRRCQKLENDADRVRTRKWGPRTLDVDIVQ------IRNGEQELLSDDPVLTLPH 114 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGV 168 P A RAFVL+PWL V+ +A L V L+ ++PT+ EGV Sbjct: 115 PWAWQRAFVLIPWLEVEPNAVL----HGTAVAALVENLDPTDIEGV 156 >tr|C8NK06|C8NK06_COREF Tax_Id=196164 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; EC=2.7.6.3;[Corynebacterium efficiens YS-314] Length = 162 Score = 116 bits (291), Expect = 1e-24 Identities = 70/166 (42%), Positives = 93/166 (56%), Gaps = 11/166 (6%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+ DR A LQ S +Y T PWG +Q FLNAV++ D Sbjct: 2 RAVLSIGSNMDDRYALLQGVIDEFRDNLVAVSSIYATPPWGVEDQDEFLNAVLVVDVDGI 61 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 + L R Q+LE +A RVR ++WG RTLDVD++ G E+++ + LTLPH Sbjct: 62 PIEL-LRRCQKLENDADRVRTRKWGPRTLDVDIVQ------IRNGEQELLSDDPVLTLPH 114 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGV 168 P A RAFVL+PWL V+ +A L V L+ ++PT+ EGV Sbjct: 115 PWAWQRAFVLIPWLEVEPNAVL----HGTAVAALVENLDPTDIEGV 156 >tr|Q6NF97|Q6NF97_CORDI Tax_Id=1717 (folK)SubName: Full=Putative 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; EC=2.7.6.3;[Corynebacterium diphtheriae] Length = 159 Score = 114 bits (286), Expect = 4e-24 Identities = 69/154 (44%), Positives = 85/154 (55%), Gaps = 6/154 (3%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+ DR A L++ S +Y T PWG +Q FLNAVVI D + Sbjct: 2 RAVLSIGSNMDDRYALLRTVVEEFAGQIVAASSIYSTPPWGVEDQYEFLNAVVIVDVDSS 61 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 + L R Q LE A R R + WG RTLDVD+++ Y G ++ + + LTLPH Sbjct: 62 PLEL-LRRGQRLEEAACRRRLRHWGPRTLDVDVVTIYNDDG-----TQMRSTDPELTLPH 115 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRL 156 P AH RAFVLVPW D +AEL AQR L Sbjct: 116 PYAHERAFVLVPWAEADPEAELLGQKVAQRAAAL 149 >tr|C3PJE5|C3PJE5_CORA7 Tax_Id=548476 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; EC=2.7.6.3;[Corynebacterium aurimucosum] Length = 156 Score = 114 bits (286), Expect = 4e-24 Identities = 74/167 (44%), Positives = 90/167 (53%), Gaps = 15/167 (8%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+ DR A LQ+ SPV+ T PWG +Q FLNAV+I D Sbjct: 2 RAVLSIGSNMEDRRALLQTVFDEFAAETVAASPVFATPPWGVTDQDEFLNAVLIVDVECT 61 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 + L R Q+LE A RVR + WG RTLDVD++ Q G T+ + LTLPH Sbjct: 62 PLEL-LRRGQKLEEAAERVRVRHWGPRTLDVDIV---QIDGVTSD-------DPELTLPH 110 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVR 169 P AH RAFVLVPWLA D A L V L+A ++ E V+ Sbjct: 111 PYAHERAFVLVPWLAADEHARL----NGTPVRELIAGLDEDEVAAVK 153 >tr|C0XP54|C0XP54_9CORY Tax_Id=525263 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; EC=2.7.6.3;[Corynebacterium lipophiloflavum DSM 44291] Length = 152 Score = 114 bits (286), Expect = 4e-24 Identities = 74/157 (47%), Positives = 87/157 (55%), Gaps = 11/157 (7%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLS GSN+ D A L S S +Y T PWG VEQ FLN V+I D Sbjct: 2 RAVLSTGSNIEDSRAHLASVVDEFADELVAASCLYATAPWGGVEQNDFLNQVLIVDVEQS 61 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 + L R Q LE+ A RVR +RWG RTLDVD++ G T+ E LT+PH Sbjct: 62 PIEL-LRRCQSLEQRARRVREKRWGPRTLDVDIVLI---DGFTSRNPE-------LTVPH 110 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAE 159 PRAH RAFVLVPWL +D DA+L A VD+L AE Sbjct: 111 PRAHERAFVLVPWLEIDPDAQLGGRSVAGIVDKLGAE 147 >tr|C2CS34|C2CS34_CORST Tax_Id=525268 (folK)SubName: Full=2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; EC=2.7.6.3;[Corynebacterium striatum ATCC 6940] Length = 155 Score = 114 bits (284), Expect = 7e-24 Identities = 75/167 (44%), Positives = 93/167 (55%), Gaps = 15/167 (8%) Query: 3 RVVLSIGSNLGDRLAWLQSXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIADGPAY 62 R VLSIGSN+ DR A LQ+ SPVY T PWG +Q FLNAV+I + + Sbjct: 2 RAVLSIGSNMDDRRALLQTVFDEFAEETVAVSPVYSTPPWGVEDQDEFLNAVLIVEVNST 61 Query: 63 DTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESNLTLPH 122 + L R Q LE++A RVR + WG RTLDVD++ Q G T+ + LTLPH Sbjct: 62 PMEL-LRRGQGLEQDAERVRVRHWGPRTLDVDIV---QVDGITSE-------DPELTLPH 110 Query: 123 PRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVR 169 P A RAFVLVPWLA D A L A L+A ++P E E V+ Sbjct: 111 PFARERAFVLVPWLAADPKARLGDTAVAD----LVAGLDPHEVEQVK 153 >tr|Q47KU9|Q47KU9_THEFY Tax_Id=269800 SubName: Full=7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; EC=2.7.6.3;[Thermobifida fusca] Length = 174 Score = 113 bits (282), Expect = 1e-23 Identities = 72/173 (41%), Positives = 95/173 (54%), Gaps = 15/173 (8%) Query: 2 TRVVLSIGSNLGDRLAWLQ----SXXXXXXXXXXXXSPVYDTVPWGAVEQRSFLNAVVIA 57 +RVVL++GSNLGDRLA LQ + SPVY+T P G EQ +LNAV +A Sbjct: 9 SRVVLALGSNLGDRLAALQGALDALADPDALRLLAVSPVYETAPVGGPEQDDYLNAVAVA 68 Query: 58 DGPAYDTKAWLCRAQELERNAGRVRGQRWGARTLDVDLISCYQTSGATTGAVEVITCESN 117 + +A L RAQ++E+ RVR RWG RTLDVD+I ++ + Sbjct: 69 E-TVLAPEALLARAQQVEKEFHRVRDVRWGPRTLDVDIIDY----------AALVRTDPE 117 Query: 118 LTLPHPRAHLRAFVLVPWLAVDSDAELTVAGRAQRVDRLLAEMEPTEREGVRL 170 LTLPHPRAH RAFVL PW +D A L G + + +A+ E R+ + L Sbjct: 118 LTLPHPRAHERAFVLRPWADIDPAAVLPGRGAVRDLLAGVADQEVRRRDDLVL 170 Database: Amellifera_nr Posted date: Jan 15, 2010 5:10 AM Number of letters in database: 3,808,957,724 Number of sequences in database: 11,153,314 Lambda K H 0.318 0.132 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11153314 Number of Hits to DB: 1,284,257,357 Number of extensions: 46739922 Number of successful extensions: 93507 Number of sequences better than 10.0: 1555 Number of HSP's gapped: 91432 Number of HSP's successfully gapped: 1557 Length of query: 191 Length of database: 3,808,957,724 Length adjustment: 130 Effective length of query: 61 Effective length of database: 2,359,026,904 Effective search space: 143900641144 Effective search space used: 143900641144 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 76 (33.9 bits)