BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ML0322
         (158 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,153,314 sequences; 3,808,957,724 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|Q9CCW5|ISPF_MYCLE Tax_Id=1769 (ispF)RecName: Full=2-C-methyl-...   281   2e-74
sp|B8ZUA8|ISPF_MYCLB Tax_Id=561304 (ispF)RecName: Full=2-C-methy...   281   2e-74
sp|B2HJ22|ISPF_MYCMM Tax_Id=216594 (ispF)RecName: Full=2-C-methy...   221   3e-56
sp|P65183|ISPF_MYCTU Tax_Id=1773 (ispF)RecName: Full=2-C-methyl-...   218   2e-55
sp|A5U8Q6|ISPF_MYCTA Tax_Id=419947 (ispF)RecName: Full=2-C-methy...   218   2e-55
sp|C1AI40|ISPF_MYCBT Tax_Id=561275 (ispF)RecName: Full=2-C-methy...   218   2e-55
sp|A1KPR7|ISPF_MYCBP Tax_Id=410289 (ispF)RecName: Full=2-C-methy...   218   2e-55
sp|P65184|ISPF_MYCBO Tax_Id=1765 (ispF)RecName: Full=2-C-methyl-...   218   2e-55
tr|C6DMN3|C6DMN3_MYCTK Tax_Id=478434 RecName: Full=2-C-methyl-D-...   218   2e-55
tr|A5WTF0|A5WTF0_MYCTF Tax_Id=336982 RecName: Full=2-C-methyl-D-...   218   2e-55
tr|A4KM66|A4KM66_MYCTU Tax_Id=395095 RecName: Full=2-C-methyl-D-...   218   2e-55
tr|A2VPY9|A2VPY9_MYCTU Tax_Id=348776 RecName: Full=2-C-methyl-D-...   218   2e-55
tr|A0PV28|A0PV28_MYCUA Tax_Id=362242 (ispF)RecName: Full=2-C-met...   213   4e-54
sp|Q743W4|ISPF_MYCPA Tax_Id=1770 (ispF)RecName: Full=2-C-methyl-...   209   1e-52
sp|A0QAB4|ISPF_MYCA1 Tax_Id=243243 (ispF)RecName: Full=2-C-methy...   209   1e-52
tr|Q1B2P2|Q1B2P2_MYCSS Tax_Id=164756 RecName: Full=2-C-methyl-D-...   198   1e-49
tr|A1UMF6|A1UMF6_MYCSK Tax_Id=189918 RecName: Full=2-C-methyl-D-...   198   1e-49
tr|A3Q6W1|A3Q6W1_MYCSJ Tax_Id=164757 RecName: Full=2-C-methyl-D-...   197   2e-49
sp|A1TG10|ISPF_MYCVP Tax_Id=350058 (ispF)RecName: Full=2-C-methy...   193   4e-48
tr|A4T5L7|A4T5L7_MYCGI Tax_Id=350054 RecName: Full=2-C-methyl-D-...   193   6e-48
sp|B1MGY4|ISPF_MYCA9 Tax_Id=561007 (ispF)RecName: Full=2-C-methy...   191   2e-47
sp|Q5Z2R2|ISPF_NOCFA Tax_Id=37329 (ispF)RecName: Full=2-C-methyl...   186   7e-46
sp|Q0S889|ISPF_RHOSR Tax_Id=101510 (ispF)RecName: Full=2-C-methy...   184   2e-45
sp|C1BAC3|ISPF_RHOOB Tax_Id=632772 (ispF)RecName: Full=2-C-methy...   183   5e-45
tr|C3JUN0|C3JUN0_RHOER Tax_Id=596309 (ispF)RecName: Full=2-C-met...   181   2e-44
sp|C0ZPR8|ISPF_RHOE4 Tax_Id=234621 (ispF)RecName: Full=2-C-methy...   181   3e-44
tr|A0R559|A0R559_MYCS2 Tax_Id=246196 (ispF)RecName: Full=2-C-met...   178   1e-43
tr|C8XAB3|C8XAB3_NAKMY Tax_Id=479431 SubName: Full=2-C-methyl-D-...   175   1e-42
tr|C0U9Y4|C0U9Y4_9ACTO Tax_Id=526225 RecName: Full=2-C-methyl-D-...   175   1e-42
tr|D0L459|D0L459_9ACTO Tax_Id=526226 SubName: Full=2C-methyl-D-e...   172   1e-41
tr|A4F6W4|A4F6W4_SACEN Tax_Id=405948 (ispF)RecName: Full=2-C-met...   167   4e-40
tr|C7MQ49|C7MQ49_SACVD Tax_Id=471857 RecName: Full=2-C-methyl-D-...   166   8e-40
tr|C6WGL5|C6WGL5_ACTMD Tax_Id=446462 RecName: Full=2-C-methyl-D-...   164   3e-39
tr|C2A7K0|C2A7K0_THECU Tax_Id=471852 RecName: Full=2-C-methyl-D-...   162   1e-38
sp|A4XCN1|ISPF_SALTO Tax_Id=369723 (ispF)RecName: Full=2-C-methy...   159   9e-38
tr|C4RE02|C4RE02_9ACTO Tax_Id=219305 RecName: Full=2-C-methyl-D-...   157   4e-37
sp|A8M7S7|ISPF_SALAI Tax_Id=391037 (ispF)RecName: Full=2-C-methy...   156   8e-37
sp|A8LF85|ISPF_FRASN Tax_Id=298653 (ispF)RecName: Full=2-C-methy...   155   2e-36
sp|B1VIQ0|ISPF_CORU7 Tax_Id=504474 (ispF)RecName: Full=2-C-methy...   153   7e-36
tr|C2CS56|C2CS56_CORST Tax_Id=525268 (ispF)RecName: Full=2-C-met...   153   7e-36
tr|C3PJB9|C3PJB9_CORA7 Tax_Id=548476 (ispF)RecName: Full=2-C-met...   152   9e-36
tr|C4ENT5|C4ENT5_STRRS Tax_Id=479432 RecName: Full=2-C-methyl-D-...   150   4e-35
sp|Q4JXJ6|ISPF_CORJK Tax_Id=306537 (ispF)RecName: Full=2-C-methy...   150   6e-35
sp|Q8NMB9|ISPF_CORGL Tax_Id=1718 (ispF)RecName: Full=2-C-methyl-...   150   6e-35
sp|Q6NFC2|ISPF_CORDI Tax_Id=1717 (ispF)RecName: Full=2-C-methyl-...   149   7e-35
tr|C0WGV4|C0WGV4_9CORY Tax_Id=525260 (ispF)RecName: Full=2-C-met...   149   7e-35
tr|B5GP17|B5GP17_STRCL Tax_Id=443255 RecName: Full=2-C-methyl-D-...   149   7e-35
sp|Q47KT3|ISPF_THEFY Tax_Id=269800 (ispF)RecName: Full=2-C-methy...   149   1e-34
sp|A0LQZ7|ISPF_ACIC1 Tax_Id=351607 (ispF)RecName: Full=2-C-methy...   149   1e-34
tr|B5H5C9|B5H5C9_STRPR Tax_Id=457429 RecName: Full=2-C-methyl-D-...   147   3e-34

>sp|Q9CCW5|ISPF_MYCLE Tax_Id=1769 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium leprae]
          Length = 158

 Score =  281 bits (719), Expect = 2e-74
 Identities = 142/158 (89%), Positives = 143/158 (90%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +SELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD
Sbjct: 1   MSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL
Sbjct: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           SALLRAPVSVAA               SAIATALVVQV
Sbjct: 121 SALLRAPVSVAATTTEGLGLTGRGEGLSAIATALVVQV 158


>sp|B8ZUA8|ISPF_MYCLB Tax_Id=561304 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium leprae]
          Length = 158

 Score =  281 bits (719), Expect = 2e-74
 Identities = 142/158 (89%), Positives = 143/158 (90%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +SELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD
Sbjct: 1   MSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL
Sbjct: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           SALLRAPVSVAA               SAIATALVVQV
Sbjct: 121 SALLRAPVSVAATTTEGLGLTGRGEGLSAIATALVVQV 158


>sp|B2HJ22|ISPF_MYCMM Tax_Id=216594 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium marinum]
          Length = 165

 Score =  221 bits (562), Expect = 3e-56
 Identities = 112/155 (72%), Positives = 120/155 (77%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVA HALCDAVLSAAG GDIG 
Sbjct: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
           +F VGDPRWE VSGA MLRHVVEL+ +HGY V NASVQV+GNRPKIG RR EAQ +LS L
Sbjct: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           L APVSV+A               +AIATALVV +
Sbjct: 124 LNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>sp|P65183|ISPF_MYCTU Tax_Id=1773 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>sp|A5U8Q6|ISPF_MYCTA Tax_Id=419947 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>sp|C1AI40|ISPF_MYCBT Tax_Id=561275 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>sp|A1KPR7|ISPF_MYCBP Tax_Id=410289 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>sp|P65184|ISPF_MYCBO Tax_Id=1765 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>tr|C6DMN3|C6DMN3_MYCTK Tax_Id=478434 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>tr|A5WTF0|A5WTF0_MYCTF Tax_Id=336982 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>tr|A4KM66|A4KM66_MYCTU Tax_Id=395095 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium tuberculosis str.
           Haarlem]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>tr|A2VPY9|A2VPY9_MYCTU Tax_Id=348776 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium tuberculosis C]
          Length = 159

 Score =  218 bits (554), Expect = 2e-55
 Identities = 111/158 (70%), Positives = 122/158 (77%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           +++LPRVGLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVAVHALCDAVLSAAG GD
Sbjct: 1   MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           IG +F V DPRW+ VSGADMLRHVV L+ +HGY V NA VQVIGNRPKIG RR EAQ +L
Sbjct: 61  IGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           S LL APVSV+A               +AIATALVV +
Sbjct: 121 SRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSL 158


>tr|A0PV28|A0PV28_MYCUA Tax_Id=362242 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium ulcerans]
          Length = 159

 Score =  213 bits (543), Expect = 4e-54
 Identities = 108/152 (71%), Positives = 117/152 (76%)

Query: 7   VGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLFA 66
           +GLG DVH  EPGRPCWLVGLLFP  DGCAGHSDGDVA HALCDAVLSAAG GDIG +F 
Sbjct: 1   MGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVFG 60

Query: 67  VGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLRA 126
           VGDPRWE VSGA MLRHVVEL+ +HGY V NASVQV+GNRPKIG RR EAQ +LS LL A
Sbjct: 61  VGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLNA 120

Query: 127 PVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           PVSV+A               +AIATALVV +
Sbjct: 121 PVSVSATTTDGLGLTGRGEGLAAIATALVVSL 152


>sp|Q743W4|ISPF_MYCPA Tax_Id=1770 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium paratuberculosis]
          Length = 159

 Score =  209 bits (531), Expect = 1e-52
 Identities = 104/152 (68%), Positives = 115/152 (75%)

Query: 5   PRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGL 64
           PR+GLG DVH  +PGRPC L+GLLF D DGCAGHSDGDV  HALCDAVLSAAG GD+G +
Sbjct: 5   PRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGDVGAV 64

Query: 65  FAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALL 124
           F V DPRW  VSGADMLRHV +L  RHG+ V NA+VQVIGNRPK+GPRR EAQR+LS LL
Sbjct: 65  FGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVLSELL 124

Query: 125 RAPVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
            APVSVAA               +AIATALVV
Sbjct: 125 GAPVSVAATTTDGLGLTGRGEGLAAIATALVV 156


>sp|A0QAB4|ISPF_MYCA1 Tax_Id=243243 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium avium]
          Length = 159

 Score =  209 bits (531), Expect = 1e-52
 Identities = 104/152 (68%), Positives = 115/152 (75%)

Query: 5   PRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGL 64
           PR+GLG DVH  +PGRPC L+GLLF D DGCAGHSDGDV  HALCDAVLSAAG GD+G +
Sbjct: 5   PRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGDVGAV 64

Query: 65  FAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALL 124
           F V DPRW  VSGADMLRHV +L  RHG+ V NA+VQVIGNRPK+GPRR EAQR+LS LL
Sbjct: 65  FGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVLSELL 124

Query: 125 RAPVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
            APVSVAA               +AIATALVV
Sbjct: 125 GAPVSVAATTTDGLGLTGRGEGLAAIATALVV 156


>tr|Q1B2P2|Q1B2P2_MYCSS Tax_Id=164756 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  198 bits (504), Expect = 1e-49
 Identities = 103/153 (67%), Positives = 112/153 (73%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           LPRVGLG DVH  EPGRPC L+GL F   DGCAGHSDGDVA HALCDA+LSAAG GD+GG
Sbjct: 3   LPRVGLGTDVHPIEPGRPCRLLGLHFDGEDGCAGHSDGDVAAHALCDALLSAAGLGDLGG 62

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
           +F  G P WE VSGADMLRHV  LL   G+ V NA+VQVIGNRPKIGPRR EAQ LLS L
Sbjct: 63  VFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLSEL 122

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           + APVSV+A               +AIATALVV
Sbjct: 123 IGAPVSVSATTTDGLGLTGRGEGLAAIATALVV 155


>tr|A1UMF6|A1UMF6_MYCSK Tax_Id=189918 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  198 bits (504), Expect = 1e-49
 Identities = 103/153 (67%), Positives = 112/153 (73%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           LPRVGLG DVH  EPGRPC L+GL F   DGCAGHSDGDVA HALCDA+LSAAG GD+GG
Sbjct: 3   LPRVGLGTDVHPIEPGRPCRLLGLHFDGEDGCAGHSDGDVAAHALCDALLSAAGLGDLGG 62

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
           +F  G P WE VSGADMLRHV  LL   G+ V NA+VQVIGNRPKIGPRR EAQ LLS L
Sbjct: 63  VFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLSEL 122

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           + APVSV+A               +AIATALVV
Sbjct: 123 IGAPVSVSATTTDGLGLTGRGEGLAAIATALVV 155


>tr|A3Q6W1|A3Q6W1_MYCSJ Tax_Id=164757 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  197 bits (502), Expect = 2e-49
 Identities = 103/153 (67%), Positives = 112/153 (73%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           LPRVGLG DVH  EPGRPC L+GL F   DGCAGHSDGDVA HALCDA+LSAAG GD+GG
Sbjct: 3   LPRVGLGTDVHPIEPGRPCRLLGLHFDGADGCAGHSDGDVAAHALCDALLSAAGLGDLGG 62

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
           +F  G P WE VSGADMLRHV  LL   G+ V NA+VQVIGNRPKIGPRR EAQ LLS L
Sbjct: 63  VFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLSEL 122

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           + APVSV+A               +AIATALVV
Sbjct: 123 IGAPVSVSATTTDGLGLTGRGEGLAAIATALVV 155


>sp|A1TG10|ISPF_MYCVP Tax_Id=350058 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium vanbaalenii]
          Length = 162

 Score =  193 bits (491), Expect = 4e-48
 Identities = 99/151 (65%), Positives = 110/151 (72%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVGLG DVH  E GRPCWL+ LLF D DGCAGHSDGDVA HALCDA+LSAAG GDIG +F
Sbjct: 6   RVGLGTDVHPIEAGRPCWLLCLLFDDADGCAGHSDGDVAAHALCDALLSAAGMGDIGEVF 65

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G P+W  VSGADMLRHV  ++   G  V NA+VQVIGNRPKIGPRR EAQR+LS +L 
Sbjct: 66  GTGLPQWRGVSGADMLRHVHSMMTAEGLRVGNAAVQVIGNRPKIGPRRAEAQRVLSGILG 125

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           APVSV+A               +AIATALVV
Sbjct: 126 APVSVSATTTDGLGLTGRGEGLAAIATALVV 156


>tr|A4T5L7|A4T5L7_MYCGI Tax_Id=350054 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium gilvum]
          Length = 160

 Score =  193 bits (490), Expect = 6e-48
 Identities = 100/151 (66%), Positives = 112/151 (74%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVGLG DVH  E GRPC L+ LLF D DGCAGHSDGDVA HALCDA+LSAAG GDIG +F
Sbjct: 5   RVGLGTDVHPIEAGRPCRLLCLLFDDGDGCAGHSDGDVAAHALCDALLSAAGMGDIGEVF 64

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G P+W  VSGADMLRHV  LL+  G++V NA+VQVIGNRPKIGPRR EAQR+LS LL 
Sbjct: 65  GTGLPQWRDVSGADMLRHVHTLLVEQGFQVGNAAVQVIGNRPKIGPRRAEAQRILSELLD 124

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           APVSV+A               +AIATALV+
Sbjct: 125 APVSVSATTTDGLGLTGRGEGLAAIATALVL 155


>sp|B1MGY4|ISPF_MYCA9 Tax_Id=561007 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium abscessus]
          Length = 158

 Score =  191 bits (486), Expect = 2e-47
 Identities = 93/155 (60%), Positives = 113/155 (72%)

Query: 1   VSELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGD 60
           ++ LPRVG+G DVH  E G+PCWL+GLLF D +GC GHSDGDVA HALCDA+LSAAG GD
Sbjct: 1   MNALPRVGIGTDVHPIEEGKPCWLLGLLFSDENGCEGHSDGDVAAHALCDALLSAAGLGD 60

Query: 61  IGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLL 120
           +G +F  G P W  VSGA ML HV +LL  +G+++ NA+VQVIGNRPK+GPRR EAQ LL
Sbjct: 61  VGAVFGTGRPEWTGVSGAKMLSHVRDLLHDNGFQIGNAAVQVIGNRPKVGPRRAEAQELL 120

Query: 121 SALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           S L+ APVSV+A               +A+ATALV
Sbjct: 121 SGLIGAPVSVSATTTDGLGLTGRGEGLAAVATALV 155


>sp|Q5Z2R2|ISPF_NOCFA Tax_Id=37329 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Nocardia farcinica]
          Length = 155

 Score =  186 bits (472), Expect = 7e-46
 Identities = 93/150 (62%), Positives = 106/150 (70%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVG+G DVH  EPGRPCW+ GLLF   DGC+GHSDGDVA HALCDA+LSAAG GD+G +F
Sbjct: 2   RVGIGSDVHPIEPGRPCWMAGLLFEGEDGCSGHSDGDVAAHALCDALLSAAGLGDVGAVF 61

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G P W  VSGA ML  V  LL   G+EVVNA+VQVIGNRPKIGPRR EAQR+L  LL 
Sbjct: 62  GTGRPEWADVSGAAMLTEVRRLLGEAGFEVVNAAVQVIGNRPKIGPRRAEAQRVLGDLLD 121

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           APVSV+                +A+ATAL+
Sbjct: 122 APVSVSGTTTDGLGLTGRGEGIAAVATALL 151


>sp|Q0S889|ISPF_RHOSR Tax_Id=101510 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus sp.]
          Length = 158

 Score =  184 bits (468), Expect = 2e-45
 Identities = 92/151 (60%), Positives = 108/151 (71%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVG+G DVH  E GRPCW+ GLLF D +GCAGHSDGDVAVHALCDA+LSAAG GD+G +F
Sbjct: 2   RVGIGTDVHPIEQGRPCWMAGLLFEDENGCAGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G P W  VSGA ML  V  LL    ++V NA+VQVIGNRPKIGPRR EAQ++LS +L 
Sbjct: 62  GTGRPEWSGVSGAAMLAEVRRLLEEDDFDVANAAVQVIGNRPKIGPRRNEAQKVLSDILG 121

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           APVSV+A               +A+ATALV+
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAMATALVI 152


>sp|C1BAC3|ISPF_RHOOB Tax_Id=632772 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus opacus]
          Length = 158

 Score =  183 bits (465), Expect = 5e-45
 Identities = 92/151 (60%), Positives = 108/151 (71%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVG+G DVH  E GRPCW+ GLLF D +GCAGHSDGDVAVHALCDA+LSAAG GD+G +F
Sbjct: 2   RVGIGTDVHPIEQGRPCWMAGLLFEDENGCAGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G P W  VSGA ML  V  LL +  + V NA+VQVIGNRPKIGPRR EAQ++LS +L 
Sbjct: 62  GTGRPEWSGVSGAAMLAEVRRLLEQDDFGVANAAVQVIGNRPKIGPRRNEAQKVLSDILG 121

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           APVSV+A               +A+ATALV+
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAMATALVI 152


>tr|C3JUN0|C3JUN0_RHOER Tax_Id=596309 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Rhodococcus erythropolis SK121]
          Length = 158

 Score =  181 bits (460), Expect = 2e-44
 Identities = 92/151 (60%), Positives = 109/151 (72%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVGLG DVH  E GRPCW+ GLLF + DGC+GHSDGDVAVHALCDA+LSAAG GD+G +F
Sbjct: 2   RVGLGTDVHPIEVGRPCWMAGLLFEEADGCSGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G P W+ VSGA ML  V  LL  + + V NA+VQVIGNRPKIGPRR EAQ++LS +L 
Sbjct: 62  GTGRPEWDGVSGARMLAEVRRLLEENQFAVGNAAVQVIGNRPKIGPRRDEAQKVLSEILG 121

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           APVSV+A               +A+ATALV+
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAMATALVM 152


>sp|C0ZPR8|ISPF_RHOE4 Tax_Id=234621 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus erythropolis]
          Length = 158

 Score =  181 bits (458), Expect = 3e-44
 Identities = 92/151 (60%), Positives = 109/151 (72%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVGLG DVH  E GRPCW+ GLLF + DGC+GHSDGDVAVHALCDA+LSAAG GD+G +F
Sbjct: 2   RVGLGTDVHPIEVGRPCWMAGLLFEEADGCSGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G P W+ VSGA ML  V  LL  + + V NA+VQVIGNRPKIGPRR EAQ++LS +L 
Sbjct: 62  GTGRPEWDGVSGARMLAEVRRLLEENQFTVGNAAVQVIGNRPKIGPRRGEAQKVLSDILG 121

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           APVSV+A               +A+ATALV+
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAMATALVM 152


>tr|A0R559|A0R559_MYCS2 Tax_Id=246196 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium smegmatis]
          Length = 163

 Score =  178 bits (452), Expect = 1e-43
 Identities = 92/152 (60%), Positives = 108/152 (71%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           LPRVGLG DVH  E GRPC L+ L F D DGCAGHSDGDVA HALCDA+LSAAG GD+G 
Sbjct: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHALCDALLSAAGLGDLGT 62

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
           +F    P+W   SGADM+RHV  L+   G+ + NA+VQVIGNRPK+GPRR EAQ++LS L
Sbjct: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           + APVSV+A               +AIATALV
Sbjct: 123 VGAPVSVSATTTDGLGLTGRGEGLAAIATALV 154


>tr|C8XAB3|C8XAB3_NAKMY Tax_Id=479431 SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Nakamurella multipartita]
          Length = 381

 Score =  175 bits (444), Expect = 1e-42
 Identities = 87/150 (58%), Positives = 101/150 (67%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVG G DVH  EPGR CW+ GLLF D DGCAGHSDGDVA HALCDA+LSAAG GD+G +F
Sbjct: 229 RVGSGIDVHPIEPGRDCWVAGLLFEDADGCAGHSDGDVAAHALCDALLSAAGLGDLGAVF 288

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
              DPRW   SGA +L  VV  +   GY+V+NASVQVI N PK+ PRR EAQ+ LSA++ 
Sbjct: 289 GTSDPRWSGASGATLLAEVVARVKAAGYQVINASVQVIANTPKLSPRRVEAQQALSAVVG 348

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALV 155
            PVSVA                +A ATAL+
Sbjct: 349 GPVSVAGTTTDGLGLTGRGEGRAATATALL 378


>tr|C0U9Y4|C0U9Y4_9ACTO Tax_Id=526225 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Geodermatophilus obscurus DSM
           43160]
          Length = 167

 Score =  175 bits (444), Expect = 1e-42
 Identities = 90/156 (57%), Positives = 106/156 (67%)

Query: 2   SELPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDI 61
           SELPRVG+G DVH    GR CWL GL +P  DGCAGHSDGDV  HAL DAVLSAAG GDI
Sbjct: 3   SELPRVGVGVDVHPVAAGRTCWLAGLQWPGVDGCAGHSDGDVVAHALTDAVLSAAGLGDI 62

Query: 62  GGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLS 121
           GGL    DPRW    GA +L HV E+L   G++V NA+VQ++GN PK+GPRR EA+++LS
Sbjct: 63  GGLLGTDDPRWAGARGAAVLAHVREVLETAGWQVGNAAVQLVGNTPKVGPRRAEAEQVLS 122

Query: 122 ALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQ 157
             L APVSV A               +A+ATALVV+
Sbjct: 123 RALGAPVSVTATTTDGLGLTGRGEGRAAMATALVVR 158


>tr|D0L459|D0L459_9ACTO Tax_Id=526226 SubName:
           Full=2C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Gordonia bronchialis DSM 43247]
          Length = 152

 Score =  172 bits (435), Expect = 1e-41
 Identities = 86/150 (57%), Positives = 100/150 (66%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVG+G D H  +    CW+VGL FPD  GCAGHSDGDV  HALCDAVLSAAG GD+G +F
Sbjct: 2   RVGIGTDAHRVDENCDCWMVGLHFPDTPGCAGHSDGDVGAHALCDAVLSAAGLGDVGSVF 61

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G P W  VSG  ML HV  L+   G+ VVN +VQVIGNRPKIGPRR EAQ++LS  L 
Sbjct: 62  GTGRPEWAGVSGVAMLAHVATLVADAGFTVVNGAVQVIGNRPKIGPRRDEAQQVLSEALG 121

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           APVSV+A               +A+ATAL+
Sbjct: 122 APVSVSATTTDGLGMTGRGEGVAAVATALI 151


>tr|A4F6W4|A4F6W4_SACEN Tax_Id=405948 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Saccharopolyspora erythraea]
          Length = 158

 Score =  167 bits (422), Expect = 4e-40
 Identities = 82/155 (52%), Positives = 102/155 (65%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PR+G G DVH  E GR CW+ GLL+P  DGCAGHSDGDVA HALCDA+LSAAG GD+G 
Sbjct: 2   IPRIGQGVDVHPVEAGRECWVAGLLWPGEDGCAGHSDGDVASHALCDALLSAAGLGDLGA 61

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
           +F  GD RW    GA++L      +   G+ + NA VQV+GNRP+IG RR EAQR+LS +
Sbjct: 62  VFGTGDDRWAGAHGAELLTEARRRVTEAGFGIGNAVVQVVGNRPRIGKRREEAQRVLSEV 121

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           + APVSV+                +A+ATALV  V
Sbjct: 122 VGAPVSVSGTTTDGLGLTGRGEGIAAVATALVFPV 156


>tr|C7MQ49|C7MQ49_SACVD Tax_Id=471857 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Saccharomonospora viridis]
          Length = 157

 Score =  166 bits (420), Expect = 8e-40
 Identities = 85/151 (56%), Positives = 100/151 (66%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           R+G G DVH  EPGR CWL GL +PD DGC+GHSDGDVA HALCDA+LSAAG GD+G +F
Sbjct: 2   RIGQGVDVHPIEPGRECWLAGLHWPDADGCSGHSDGDVASHALCDALLSAAGLGDLGAVF 61

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
             G  +W    G ++L  V   +   GY V NA VQVIGNRPKIG RR EAQR+LS  + 
Sbjct: 62  GTGQNQWAGAHGVELLAEVRTRVTEAGYRVGNAVVQVIGNRPKIGRRREEAQRVLSEAVG 121

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
           APVSV+A               +AIATAL+V
Sbjct: 122 APVSVSATTTDGLGLTGRGEGIAAIATALLV 152


>tr|C6WGL5|C6WGL5_ACTMD Tax_Id=446462 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Actinosynnema mirum]
          Length = 155

 Score =  164 bits (415), Expect = 3e-39
 Identities = 80/151 (52%), Positives = 100/151 (66%)

Query: 6   RVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           RVG+G DVH  EPGR CW+VGLL+   DGCAGHSDGDVA HALCDA+LSAAG GD+G +F
Sbjct: 2   RVGIGTDVHPVEPGRDCWMVGLLWEGADGCAGHSDGDVAAHALCDALLSAAGLGDLGAVF 61

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLR 125
              DPRW    G + L     L+   G+ V NA+VQVIGN P++G RR EAQ++LS +L 
Sbjct: 62  GTSDPRWSGAHGVEFLAEARRLVEAEGFVVGNAAVQVIGNAPRVGKRRAEAQKVLSEVLG 121

Query: 126 APVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
            PVSV+                +A+ATAL++
Sbjct: 122 GPVSVSGTTTDGLGLTGRGEGVAAVATALLL 152


>tr|C2A7K0|C2A7K0_THECU Tax_Id=471852 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Thermomonospora curvata DSM
           43183]
          Length = 156

 Score =  162 bits (410), Expect = 1e-38
 Identities = 84/152 (55%), Positives = 102/152 (67%), Gaps = 2/152 (1%)

Query: 7   VGLGFDVHVFEPGRPCWLVGLLFPDN-DGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLF 65
           +G+G DVH F  GRP W+ GLL+PD  DG  GHSDGDVA HA CDA+LSAAG GD+G +F
Sbjct: 1   MGVGTDVHPFGSGRPLWVAGLLWPDEGDGLTGHSDGDVAAHAACDALLSAAGLGDLGAVF 60

Query: 66  AVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLS-ALL 124
              DPRW   SG ++L  V  LL  HGY + N ++QVIGNRPKIG RR EA+++LS AL 
Sbjct: 61  GTADPRWRGASGTELLAEVARLLTEHGYAIGNVAIQVIGNRPKIGRRRAEAEKVLSEALG 120

Query: 125 RAPVSVAAXXXXXXXXXXXXXXXSAIATALVV 156
            APVS++A               +AIATALVV
Sbjct: 121 GAPVSLSATTTDGLGLTGRGEGLAAIATALVV 152


>sp|A4XCN1|ISPF_SALTO Tax_Id=369723 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Salinispora tropica]
          Length = 161

 Score =  159 bits (402), Expect = 9e-38
 Identities = 80/152 (52%), Positives = 96/152 (63%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRV +G D+H FE GRPCW+ GL +P  DG AGHSD DVA HA C+A+LSAA  GD+G 
Sbjct: 4   VPRVAIGVDMHAFESGRPCWVAGLHWPGQDGLAGHSDADVAAHAACNALLSAAELGDLGA 63

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
            F VG P W   SG  +L      +   GY + N SVQVIGNRPKIGPRR EAQ++LSA 
Sbjct: 64  NFGVGQPEWSGASGVALLSESARRVRTAGYTIGNVSVQVIGNRPKIGPRRAEAQQVLSAA 123

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           + APVSV+A               + IA ALV
Sbjct: 124 VGAPVSVSAATTDGLGFPGRDEGLTGIAVALV 155


>tr|C4RE02|C4RE02_9ACTO Tax_Id=219305 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12; Flags: Fragment;[Micromonospora
           sp. ATCC 39149]
          Length = 220

 Score =  157 bits (397), Expect = 4e-37
 Identities = 77/152 (50%), Positives = 95/152 (62%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRV +G DVH FE GRPCWL GLL+P  DG AGHSD DV  HA C+A+LSAAG GD+G 
Sbjct: 63  VPRVAIGTDVHAFEVGRPCWLAGLLWPGQDGLAGHSDADVVAHAACNALLSAAGLGDLGS 122

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
            F V +P W    G  +L      +   G+E+ N SVQV+GNRPKIGPRR EA+ +LS  
Sbjct: 123 NFGVAEPEWAGAPGVALLAETARRVRAAGFEIGNVSVQVVGNRPKIGPRRAEAEAVLSEA 182

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           + APV+V+A               + IA ALV
Sbjct: 183 VGAPVAVSAATTDGLGFTGRGEGLAGIAVALV 214


>sp|A8M7S7|ISPF_SALAI Tax_Id=391037 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Salinispora arenicola]
          Length = 161

 Score =  156 bits (394), Expect = 8e-37
 Identities = 78/154 (50%), Positives = 94/154 (61%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRV +G D H FE GRPCW+ GL +P  DG AGHSD DVA HA C+A+LSAA  GD+G 
Sbjct: 4   VPRVAIGVDTHAFESGRPCWVAGLHWPGQDGLAGHSDADVAAHAACNALLSAADLGDLGA 63

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
            F VG P W   SG  +L      +   GY + N SVQVIGNRPKIG RR EAQR+LS  
Sbjct: 64  NFGVGQPEWSGASGVALLTESASRVRAAGYAIGNVSVQVIGNRPKIGSRRAEAQRVLSGA 123

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQ 157
           + APVS++A               + IA ALV +
Sbjct: 124 VGAPVSISAATTDGLGFPGRGEGLTGIAVALVYE 157


>sp|A8LF85|ISPF_FRASN Tax_Id=298653 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Frankia sp.]
          Length = 160

 Score =  155 bits (391), Expect = 2e-36
 Identities = 78/155 (50%), Positives = 98/155 (63%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           LPRVG G DVH FE GR CW+  LL+P   G AGHSDGDVA HA CDA+L+A+G GD+G 
Sbjct: 6   LPRVGTGVDVHPFEQGRECWVACLLWPGETGLAGHSDGDVASHAACDALLTASGIGDLGA 65

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
           +F  G P W   SGA +L     LL   G+ + N +VQV+GNRP++  RR EAQ  +SA 
Sbjct: 66  VFGTGRPEWSGASGAALLGETARLLAEGGWLIGNVAVQVVGNRPRMAARRVEAQEAMSAA 125

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           L APV+++A               +AIATALV +V
Sbjct: 126 LGAPVNLSATTTDGLGLTGRGEGLAAIATALVTRV 160


>sp|B1VIQ0|ISPF_CORU7 Tax_Id=504474 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Corynebacterium urealyticum]
          Length = 162

 Score =  153 bits (386), Expect = 7e-36
 Identities = 73/152 (48%), Positives = 99/152 (65%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRVG+  D H  EPG+PCW+ GLLF D DGC GHSDGDV  H + DA+LSA+G GD+G 
Sbjct: 6   IPRVGIASDAHQVEPGKPCWMAGLLFEDADGCEGHSDGDVVSHVIVDALLSASGLGDLGS 65

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
              VG   ++ VSG  ++    +LL  +G+ + N + Q+IGNRPK+GPRR EA+R L+ L
Sbjct: 66  FVGVGRKEYDGVSGERLITECRQLLAENGFTIGNVAAQMIGNRPKMGPRREEAERRLTEL 125

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           + APVSV+A               +A+ATA+V
Sbjct: 126 VGAPVSVSATTTDKMGFTGRGEGVAALATAVV 157


>tr|C2CS56|C2CS56_CORST Tax_Id=525268 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Corynebacterium striatum ATCC
           6940]
          Length = 160

 Score =  153 bits (386), Expect = 7e-36
 Identities = 75/152 (49%), Positives = 98/152 (64%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRVG+  D H  E G+PCW+ GLLF   DGC GHSDGDV  HAL DA+LSA+  GD+G 
Sbjct: 6   IPRVGIATDAHQIEEGKPCWIAGLLFEGVDGCEGHSDGDVVSHALVDALLSASNLGDLGS 65

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
              VG   ++ VSG  +LR   ELL  HG+ + NA+ Q++G  PK+GPRR EA+R+LS +
Sbjct: 66  FVGVGRKEYDNVSGERLLRECRELLESHGFVIGNAAAQLVGQSPKMGPRREEAERVLSEI 125

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           L APVSV+A               +A+ATA+V
Sbjct: 126 LGAPVSVSATTTDHMGFTGRSEGRAAVATAVV 157


>tr|C3PJB9|C3PJB9_CORA7 Tax_Id=548476 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Corynebacterium aurimucosum]
          Length = 152

 Score =  152 bits (385), Expect = 9e-36
 Identities = 74/149 (49%), Positives = 98/149 (65%)

Query: 7   VGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLFA 66
           +G+  D H  EPG+PCW+ GLLF D DGC GHSDGDV  HAL DA+LSA+  GD+G    
Sbjct: 1   MGIATDAHQIEPGKPCWIAGLLFEDVDGCEGHSDGDVVSHALVDALLSASNLGDLGSFVG 60

Query: 67  VGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLRA 126
           VG P ++ VSGA +LR   ELL + G+ + NA+ Q++G  PK+GPRR EA+ +LS +L A
Sbjct: 61  VGRPEYDGVSGAQLLRECRELLEKEGFIIGNAAAQLVGQSPKMGPRRKEAEAVLSEILGA 120

Query: 127 PVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           PVSV+A               +A+ATA+V
Sbjct: 121 PVSVSATTTDHLGFTGRKEGRAAVATAVV 149


>tr|C4ENT5|C4ENT5_STRRS Tax_Id=479432 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Streptosporangium roseum DSM
           43021]
          Length = 159

 Score =  150 bits (379), Expect = 4e-35
 Identities = 75/152 (49%), Positives = 95/152 (62%)

Query: 7   VGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLFA 66
           +G+G DVH F  GR   L GL +P   G  GHSDGD A HA CDA+LSAAG GD+GGLF 
Sbjct: 1   MGVGVDVHPFASGRELHLAGLHWPGETGLDGHSDGDAAAHAACDALLSAAGLGDLGGLFG 60

Query: 67  VGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLRA 126
             DPRW   SG  +L      +   G+E+ N +VQVIGNRPK+ PRRTEA++ LSA + A
Sbjct: 61  TSDPRWAGASGVTLLEEAARKVRAAGFEIGNVAVQVIGNRPKLAPRRTEAEKALSAAVGA 120

Query: 127 PVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           PVS++A               +A+ATA+VV +
Sbjct: 121 PVSISATTTDGLGLTGRGEGVAAVATAIVVNL 152


>sp|Q4JXJ6|ISPF_CORJK Tax_Id=306537 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Corynebacterium jeikeium]
          Length = 163

 Score =  150 bits (378), Expect = 6e-35
 Identities = 73/154 (47%), Positives = 100/154 (64%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRVG+  D H  +PG+ CW+  LL+ D DGC GHSDGDV  HA+ DA+LSAAG GD+G 
Sbjct: 7   IPRVGIATDAHQVQPGKDCWMACLLWEDQDGCEGHSDGDVVAHAVVDALLSAAGLGDLGS 66

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
              VG   ++ VSG  +LR   ELL   G+ + NA+VQ++GNRPK+G RR EA++++  L
Sbjct: 67  FVGVGRQEYDNVSGERLLRECRELLESKGFVIGNAAVQMVGNRPKMGTRREEAEKVMGEL 126

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQ 157
           + APVSV+A               +A+ATA+V Q
Sbjct: 127 IGAPVSVSATTTDHMGFTGRGEGVAAVATAVVWQ 160


>sp|Q8NMB9|ISPF_CORGL Tax_Id=1718 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Corynebacterium glutamicum]
          Length = 160

 Score =  150 bits (378), Expect = 6e-35
 Identities = 70/152 (46%), Positives = 97/152 (63%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRVG+  D H  E G+PCW+  LLF   DGC GHSDGDV  HA+ DA+LSA+G GD+G 
Sbjct: 6   IPRVGIATDAHQIEAGKPCWIACLLFEGVDGCEGHSDGDVVAHAIVDALLSASGLGDLGS 65

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
              VG P ++ VSG  +L+ V ELL  HGY + N + Q++G  PK GPRR EAQ+++S +
Sbjct: 66  FVGVGRPEYDGVSGTQLLKEVRELLSAHGYVIGNVAAQLVGQTPKFGPRREEAQQVISEI 125

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           + AP S++A               +++ATA+V
Sbjct: 126 IGAPCSLSATTTDHMGFTGRSEGRASVATAVV 157


>sp|Q6NFC2|ISPF_CORDI Tax_Id=1717 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Corynebacterium diphtheriae]
          Length = 160

 Score =  149 bits (377), Expect = 7e-35
 Identities = 73/152 (48%), Positives = 96/152 (63%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRVG+  D H  E G+PCW+  LLF   DGC GHSDGDV  HAL DA+LSAA  GD+G 
Sbjct: 7   IPRVGIATDAHQIEAGKPCWIACLLFSGADGCEGHSDGDVVAHALVDALLSAANLGDLGS 66

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
              VG   ++ VSG  +L    ELL  HG+ + N +VQ++G  PK+GPRR EA+R++S +
Sbjct: 67  FVGVGRKEYDGVSGTQLLTECRELLESHGFTIGNGAVQLVGQSPKMGPRREEAERVMSEI 126

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           L APVSV+A               +A+ATA+V
Sbjct: 127 LGAPVSVSATTTDHLGFTGRSEGRAAVATAVV 158


>tr|C0WGV4|C0WGV4_9CORY Tax_Id=525260 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Corynebacterium accolens ATCC
           49725]
          Length = 162

 Score =  149 bits (377), Expect = 7e-35
 Identities = 74/152 (48%), Positives = 97/152 (63%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           +PRVG+  D H  E G+PCW+ GLLF D  GC GHSDGDV  HAL DA+LSA+  GD+G 
Sbjct: 6   IPRVGIATDAHQIEAGKPCWIAGLLFDDAPGCEGHSDGDVVAHALVDALLSASHLGDLGS 65

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
              VG P ++ VSGA +LR   ELL   G+ + NA+ Q+IG  PK+GPRR EA+ +LS +
Sbjct: 66  FVGVGRPEYDGVSGAQLLRECRELLEAEGFIIGNAAAQLIGQTPKMGPRREEAEAVLSEI 125

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           L A VS++A               +A+ATA+V
Sbjct: 126 LGADVSISATTTDHLGFTGRKEGRAAVATAVV 157


>tr|B5GP17|B5GP17_STRCL Tax_Id=443255 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Streptomyces clavuligerus ATCC
           27064]
          Length = 173

 Score =  149 bits (377), Expect = 7e-35
 Identities = 75/155 (48%), Positives = 94/155 (60%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           LP +G+G DVH FE GR  W  GL +P  DG AGHSDGDVA HA CDA+ SAAG GD+G 
Sbjct: 17  LPLIGIGTDVHAFEAGRELWCAGLHWPGEDGLAGHSDGDVAAHAACDALFSAAGVGDLGA 76

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
            F    P W   SG  +L     ++   G+ + N ++QVIG RPKIG RR EAQ++LS  
Sbjct: 77  HFGTSRPEWSGASGITLLAEAARIVRAEGFAIGNVAIQVIGVRPKIGKRRDEAQKVLSEA 136

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           + APVSV+                +AIATAL+V+V
Sbjct: 137 VGAPVSVSGTTTDGLGLTGRAEGLAAIATALLVRV 171


>sp|Q47KT3|ISPF_THEFY Tax_Id=269800 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Thermobifida fusca]
          Length = 154

 Score =  149 bits (376), Expect = 1e-34
 Identities = 74/152 (48%), Positives = 95/152 (62%)

Query: 7   VGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGGLFA 66
           VG+G DVH F+ GRP +L GL +PD  G +GHSDGDVA HA CDA+ SA   GD+G  F 
Sbjct: 2   VGVGTDVHPFQTGRPLFLAGLEWPDEVGLSGHSDGDVAAHAACDALFSACALGDLGSQFG 61

Query: 67  VGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSALLRA 126
             DPRW   SG  +L    + +   GYE+ N ++Q+IGNRPK  PRR EA+++LSA + A
Sbjct: 62  TSDPRWRGASGVALLTEAAQRVRAAGYEIGNIAIQIIGNRPKFAPRRHEAEKVLSAAVGA 121

Query: 127 PVSVAAXXXXXXXXXXXXXXXSAIATALVVQV 158
           PVS AA               +A+ATAL V+V
Sbjct: 122 PVSCAATTTDGLGFTGRGEGIAAVATALCVRV 153


>sp|A0LQZ7|ISPF_ACIC1 Tax_Id=351607 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Acidothermus cellulolyticus]
          Length = 161

 Score =  149 bits (376), Expect = 1e-34
 Identities = 73/152 (48%), Positives = 97/152 (63%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLFPDNDGCAGHSDGDVAVHALCDAVLSAAGQGDIGG 63
           LPRVG+G DVH F P RP WL GL +P   G AGHSD DV +HALC+A+LSAAG GD+G 
Sbjct: 6   LPRVGIGVDVHPFSPDRPLWLAGLHWPGEPGLAGHSDADVVIHALCNALLSAAGLGDLGT 65

Query: 64  LFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRLLSAL 123
            F   +P W   +G  +L   V L+   GY V NA+VQ++G RPK+  RRTEA++LL+  
Sbjct: 66  QFGTAEPEWRDAAGTRLLTETVRLVRDAGYAVGNAAVQLLGERPKLRERRTEAEQLLTET 125

Query: 124 LRAPVSVAAXXXXXXXXXXXXXXXSAIATALV 155
           + AP++++A               +A+ATALV
Sbjct: 126 VGAPIALSAATTDGLGFLGRRDGLAAVATALV 157


>tr|B5H5C9|B5H5C9_STRPR Tax_Id=457429 RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Streptomyces pristinaespiralis
           ATCC 25486]
          Length = 167

 Score =  147 bits (372), Expect = 3e-34
 Identities = 80/158 (50%), Positives = 98/158 (62%), Gaps = 4/158 (2%)

Query: 4   LPRVGLGFDVHVFEPGRPCWLVGLLF--PDNDG--CAGHSDGDVAVHALCDAVLSAAGQG 59
           LP+VG+G DVH FE GR  W  GLL+  P++DG   AGHSDGDVA HA CDA+ SAAG G
Sbjct: 8   LPQVGIGTDVHAFEKGRELWCAGLLWEGPESDGYGLAGHSDGDVAAHAACDALFSAAGIG 67

Query: 60  DIGGLFAVGDPRWERVSGADMLRHVVELLLRHGYEVVNASVQVIGNRPKIGPRRTEAQRL 119
           D+G  F    P W   SG  +L     ++   G+E+ N SVQVIG RPKIG RR EAQ+ 
Sbjct: 68  DLGAHFGTSRPEWSGASGVALLSEAARIVRAAGFEIGNVSVQVIGVRPKIGKRRDEAQKA 127

Query: 120 LSALLRAPVSVAAXXXXXXXXXXXXXXXSAIATALVVQ 157
           LSA + APV+V+                +AIATALVV+
Sbjct: 128 LSAAVGAPVAVSGTTTDGLGLTGRAEGLAAIATALVVR 165


  Database: Amellifera_nr
    Posted date:  Jan 15, 2010  5:10 AM
  Number of letters in database: 3,808,957,724
  Number of sequences in database:  11,153,314
  
Lambda     K      H
   0.323    0.140    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11153314
Number of Hits to DB: 1,054,735,555
Number of extensions: 41794928
Number of successful extensions: 87845
Number of sequences better than 10.0: 1477
Number of HSP's gapped: 88700
Number of HSP's successfully gapped: 1477
Length of query: 158
Length of database: 3,808,957,724
Length adjustment: 120
Effective length of query: 38
Effective length of database: 2,470,560,044
Effective search space: 93881281672
Effective search space used: 93881281672
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 75 (33.5 bits)