BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= ML0909 (530 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,153,314 sequences; 3,808,957,724 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|O69557|MURE_MYCLE Tax_Id=1769 (murE)RecName: Full=UDP-N-acety... 887 0.0 tr|B8ZQP5|B8ZQP5_MYCLB Tax_Id=561304 (murE)SubName: Full=UDP-N-a... 887 0.0 sp|Q73YQ3|MURE_MYCPA Tax_Id=1770 (murE)RecName: Full=UDP-N-acety... 645 0.0 sp|A0QF47|MURE_MYCA1 Tax_Id=243243 (murE)RecName: Full=UDP-N-ace... 645 0.0 sp|P65477|MURE_MYCTU Tax_Id=1773 (murE)RecName: Full=UDP-N-acety... 636 e-180 sp|P65478|MURE_MYCBO Tax_Id=1765 (murE)RecName: Full=UDP-N-acety... 636 e-180 tr|C6DPQ0|C6DPQ0_MYCTK Tax_Id=478434 SubName: Full=UDP-N-acetylm... 636 e-180 tr|C1AQ74|C1AQ74_MYCBT Tax_Id=561275 (murE)SubName: Full=UDP-N-a... 636 e-180 tr|A5U4I5|A5U4I5_MYCTA Tax_Id=419947 (murE)SubName: Full=UDP-N-a... 636 e-180 tr|A1KKK1|A1KKK1_MYCBP Tax_Id=410289 (murE)SubName: Full=Probabl... 636 e-180 tr|A5WPD0|A5WPD0_MYCTF Tax_Id=336982 SubName: Full=UDP-N-acetylm... 636 e-180 tr|A2VJQ4|A2VJQ4_MYCTU Tax_Id=348776 SubName: Full=UDP-N-acetylm... 636 e-180 tr|B2HGS1|B2HGS1_MYCMM Tax_Id=216594 (murE)SubName: Full=UDP-N-a... 626 e-177 tr|A0PTJ2|A0PTJ2_MYCUA Tax_Id=362242 (murE)SubName: Full=UDP-N-a... 621 e-176 tr|Q1B6W6|Q1B6W6_MYCSS Tax_Id=164756 SubName: Full=UDP-N-acetylm... 542 e-152 tr|A1UI59|A1UI59_MYCSK Tax_Id=189918 SubName: Full=UDP-N-acetylm... 542 e-152 tr|A3Q1M3|A3Q1M3_MYCSJ Tax_Id=164757 SubName: Full=UDP-N-acetylm... 540 e-151 tr|A0R021|A0R021_MYCS2 Tax_Id=246196 SubName: Full=UDP-N-acetylm... 534 e-149 tr|A1TAX3|A1TAX3_MYCVP Tax_Id=350058 SubName: Full=UDP-N-acetylm... 518 e-145 tr|A4TBF0|A4TBF0_MYCGI Tax_Id=350054 SubName: Full=UDP-N-acetylm... 506 e-141 tr|B1MP32|B1MP32_MYCA9 Tax_Id=561007 SubName: Full=UDP-N-acetylm... 452 e-125 tr|Q5YYY4|Q5YYY4_NOCFA Tax_Id=37329 (murE)SubName: Full=Putative... 403 e-110 tr|C3JJ53|C3JJ53_RHOER Tax_Id=596309 SubName: Full=UDP-N-acetylm... 402 e-110 tr|C1A0Y0|C1A0Y0_RHOE4 Tax_Id=234621 (murE)SubName: Full=UDP-N-a... 402 e-110 tr|D0LAT6|D0LAT6_9ACTO Tax_Id=526226 SubName: Full=UDP-N-acetylm... 399 e-109 tr|C1AU60|C1AU60_RHOOB Tax_Id=632772 (murE)SubName: Full=UDP-N-a... 392 e-107 tr|C6WDE7|C6WDE7_ACTMD Tax_Id=446462 SubName: Full=UDP-N-acetylm... 391 e-106 tr|A4FLW5|A4FLW5_SACEN Tax_Id=405948 (murE)SubName: Full=UDP-N-a... 388 e-106 tr|Q0SHR6|Q0SHR6_RHOSR Tax_Id=101510 (murE1)SubName: Full=UDP-N-... 387 e-105 tr|C7MV98|C7MV98_SACVD Tax_Id=471857 SubName: Full=UDP-N-acetylm... 383 e-104 tr|C0E4M8|C0E4M8_9CORY Tax_Id=566549 SubName: Full=Putative unch... 372 e-101 tr|C5VD82|C5VD82_9CORY Tax_Id=553207 SubName: Full=UDP-N-acetylm... 370 e-100 sp|Q8NNN0|MURE_CORGL Tax_Id=1718 (murE)RecName: Full=UDP-N-acety... 367 3e-99 tr|A4QFM8|A4QFM8_CORGB Tax_Id=340322 SubName: Full=Putative unch... 367 3e-99 tr|C8XGZ1|C8XGZ1_NAKMY Tax_Id=479431 SubName: Full=UDP-N-acetylm... 366 4e-99 tr|C0XS01|C0XS01_9CORY Tax_Id=525263 (murE)SubName: Full=UDP-N-a... 365 1e-98 tr|A8KZA6|A8KZA6_FRASN Tax_Id=298653 SubName: Full=UDP-N-acetylm... 361 1e-97 tr|Q6NGC3|Q6NGC3_CORDI Tax_Id=1717 (murE)SubName: Full=UDP-N-ace... 356 4e-96 tr|C4LI45|C4LI45_CORK4 Tax_Id=645127 SubName: Full=UDP-N-acetylm... 354 1e-95 sp|Q8FNT5|MURE_COREF Tax_Id=152794 (murE)RecName: Full=UDP-N-ace... 352 7e-95 tr|C8NQ17|C8NQ17_COREF Tax_Id=196164 (murE)SubName: Full=UDP-N-a... 351 2e-94 tr|A1SL85|A1SL85_NOCSJ Tax_Id=196162 SubName: Full=UDP-N-acetylm... 348 1e-93 tr|C8NTK7|C8NTK7_9CORY Tax_Id=585529 (murE)SubName: Full=UDP-N-a... 340 4e-91 tr|A8LX85|A8LX85_SALAI Tax_Id=391037 SubName: Full=UDP-N-acetylm... 338 8e-91 tr|A4X9S0|A4X9S0_SALTO Tax_Id=369723 SubName: Full=UDP-N-acetylm... 338 1e-90 tr|C2CNH9|C2CNH9_CORST Tax_Id=525268 (murE)SubName: Full=UDP-N-a... 337 2e-90 tr|Q47QX4|Q47QX4_THEFY Tax_Id=269800 SubName: Full=UDP-N-acetylm... 335 9e-90 tr|C2BNI4|C2BNI4_9CORY Tax_Id=525264 (murE)SubName: Full=UDP-N-a... 333 3e-89 tr|C6RAX4|C6RAX4_9CORY Tax_Id=553206 SubName: Full=UDP-N-acetylm... 331 1e-88 tr|Q2JD55|Q2JD55_FRASC Tax_Id=106370 SubName: Full=UDP-N-acetylm... 331 2e-88 >sp|O69557|MURE_MYCLE Tax_Id=1769 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium leprae] Length = 530 Score = 887 bits (2292), Expect = 0.0 Identities = 466/530 (87%), Positives = 467/530 (88%) Query: 1 VTEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSG 60 +TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSG Sbjct: 1 MTEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSG 60 Query: 61 DLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGL 120 DLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGL Sbjct: 61 DLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGL 120 Query: 121 AAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFL 180 AAAAYGHPSNRM E TIGIRIDGADIPSFL Sbjct: 121 AAAAYGHPSNRMTVVGITGTSGKTTTTYMVEAGLRAGGRVVGLVGTIGIRIDGADIPSFL 180 Query: 181 TTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPD 240 TTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPD Sbjct: 181 TTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPD 240 Query: 241 MEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIR 300 MEEYFEAKAVLFDPHSLLRARTVVVC VSALGQPASWRATDIR Sbjct: 241 MEEYFEAKAVLFDPHSLLRARTVVVCIDDDAGRATAARAGDAITVSALGQPASWRATDIR 300 Query: 301 SPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRI 360 SPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRI Sbjct: 301 SPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRI 360 Query: 361 PGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGE 420 PGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGE Sbjct: 361 PGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGE 420 Query: 421 IAAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGP 480 IAAELADLVVVTDDNPRGEDPAAIRRDIL EIGDRRAAIQYAVAWAGP Sbjct: 421 IAAELADLVVVTDDNPRGEDPAAIRRDILTGTVAAGGAAQVVEIGDRRAAIQYAVAWAGP 480 Query: 481 DDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARLLPAPGRACQ 530 DDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARLLPAPGRACQ Sbjct: 481 DDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARLLPAPGRACQ 530 >tr|B8ZQP5|B8ZQP5_MYCLB Tax_Id=561304 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diami nopime ligase (Meso-diaminopimelate-adding enzyme);[Mycobacterium leprae] Length = 530 Score = 887 bits (2292), Expect = 0.0 Identities = 466/530 (87%), Positives = 467/530 (88%) Query: 1 VTEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSG 60 +TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSG Sbjct: 1 MTEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSG 60 Query: 61 DLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGL 120 DLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGL Sbjct: 61 DLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGL 120 Query: 121 AAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFL 180 AAAAYGHPSNRM E TIGIRIDGADIPSFL Sbjct: 121 AAAAYGHPSNRMTVVGITGTSGKTTTTYMVEAGLRAGGRVVGLVGTIGIRIDGADIPSFL 180 Query: 181 TTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPD 240 TTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPD Sbjct: 181 TTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPD 240 Query: 241 MEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIR 300 MEEYFEAKAVLFDPHSLLRARTVVVC VSALGQPASWRATDIR Sbjct: 241 MEEYFEAKAVLFDPHSLLRARTVVVCIDDDAGRATAARAGDAITVSALGQPASWRATDIR 300 Query: 301 SPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRI 360 SPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRI Sbjct: 301 SPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRI 360 Query: 361 PGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGE 420 PGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGE Sbjct: 361 PGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGE 420 Query: 421 IAAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGP 480 IAAELADLVVVTDDNPRGEDPAAIRRDIL EIGDRRAAIQYAVAWAGP Sbjct: 421 IAAELADLVVVTDDNPRGEDPAAIRRDILTGTVAAGGAAQVVEIGDRRAAIQYAVAWAGP 480 Query: 481 DDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARLLPAPGRACQ 530 DDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARLLPAPGRACQ Sbjct: 481 DDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARLLPAPGRACQ 530 >sp|Q73YQ3|MURE_MYCPA Tax_Id=1770 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium paratuberculosis] Length = 520 Score = 645 bits (1663), Expect = 0.0 Identities = 341/512 (66%), Positives = 380/512 (74%), Gaps = 2/512 (0%) Query: 4 VVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLF 63 +V+VP LRPSA GVRLP L QVGAV+A GP + A VPD+ VTGVTLRAQ+VL GDLF Sbjct: 1 MVSVPTGLRPSAVPGVRLPALADQVGAVMA-GPDRRAAVPDVTVTGVTLRAQDVLPGDLF 59 Query: 64 AALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAA 123 AAL GA+THGAR+A A+ERGAVAVLTD AGVA+LT + P L+HP PRSVLG LAAA Sbjct: 60 AALPGATTHGARHAAEAIERGAVAVLTDAAGVAQLTG-GRTTPTLLHPRPRSVLGQLAAA 118 Query: 124 AYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTP 183 Y HPS R+ E T+GIRIDGADIPS LTTP Sbjct: 119 VYAHPSERLTVIGITGTSGKTTTTYLVESGLRAAGRTAGLIGTVGIRIDGADIPSALTTP 178 Query: 184 EAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEE 243 EAPALQA+LAAM E+ V+TVVMEVSSHAL+LGRV+GT+FAV GFTNLSRDHLDFHP M + Sbjct: 179 EAPALQALLAAMAEQRVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMAD 238 Query: 244 YFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPG 303 YFEAKA+LFDP+S LRA VVC VSA GQPA WRA ++ G Sbjct: 239 YFEAKALLFDPNSPLRAHRAVVCIDDEAGREMAARAGDAVTVSAEGQPAHWRAVEVAPLG 298 Query: 304 VGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGR 363 G Q+FT +DPAGVQHR GIRLPG YNVANCLVALA+LD VGVSPEQA+ G R+PGR Sbjct: 299 TGGQQFTVIDPAGVQHRAGIRLPGHYNVANCLVALALLDAVGVSPEQAAPGLLQTRVPGR 358 Query: 364 LERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEIAA 423 +E ID GQDFLALVDYAHKPGAL +VL++L +PD RLAVVFGAGGERDPGKRAPMG AA Sbjct: 359 MEEIDAGQDFLALVDYAHKPGALRAVLSSLKRPDRRLAVVFGAGGERDPGKRAPMGATAA 418 Query: 424 ELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDV 483 ELADLVVVTDDNPRGEDPAAIRR+IL EIGDRRAAI++AVAWAGP DV Sbjct: 419 ELADLVVVTDDNPRGEDPAAIRREILAGVTESGCAAEVVEIGDRRAAIRHAVAWAGPGDV 478 Query: 484 VLVAGKGHETGQRGAAETCPFDDRVELARALQ 515 VLVAGKGHETGQR T PFDDRVELA AL+ Sbjct: 479 VLVAGKGHETGQRTGEHTRPFDDRVELAEALR 510 >sp|A0QF47|MURE_MYCA1 Tax_Id=243243 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium avium] Length = 520 Score = 645 bits (1663), Expect = 0.0 Identities = 341/512 (66%), Positives = 380/512 (74%), Gaps = 2/512 (0%) Query: 4 VVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLF 63 +V+VP LRPSA GVRLP L QVGAV+A GP + A VPD+ VTGVTLRAQ+VL GDLF Sbjct: 1 MVSVPTGLRPSAVPGVRLPALADQVGAVMA-GPDRRAAVPDVTVTGVTLRAQDVLPGDLF 59 Query: 64 AALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAA 123 AAL GA+THGAR+A A+ERGAVAVLTD AGVA+LT + P L+HP PRSVLG LAAA Sbjct: 60 AALPGATTHGARHAAEAIERGAVAVLTDAAGVAQLTG-GRTTPTLLHPRPRSVLGELAAA 118 Query: 124 AYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTP 183 Y HPS R+ E T+GIRIDGADIPS LTTP Sbjct: 119 VYAHPSERLTVIGITGTSGKTTTTYLVESGLRAAGRTAGLIGTVGIRIDGADIPSALTTP 178 Query: 184 EAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEE 243 EAPALQA+LAAM E+ V+TVVMEVSSHAL+LGRV+GT+FAV GFTNLSRDHLDFHP M + Sbjct: 179 EAPALQALLAAMAEQRVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMAD 238 Query: 244 YFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPG 303 YFEAKA+LFDP+S LRA VVC VSA GQPA WRA ++ G Sbjct: 239 YFEAKALLFDPNSPLRAHRAVVCIDDEAGREMAARAGDAVTVSAEGQPAHWRAVEVAPLG 298 Query: 304 VGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGR 363 G Q+FT +DPAGVQHR GIRLPG YNVANCLVALA+LD VGVSPEQA+ G R+PGR Sbjct: 299 TGGQQFTVIDPAGVQHRAGIRLPGHYNVANCLVALALLDAVGVSPEQAAPGLLQTRVPGR 358 Query: 364 LERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEIAA 423 +E ID GQDFLALVDYAHKPGAL +VL++L +PD RLAVVFGAGGERDPGKRAPMG AA Sbjct: 359 MEEIDAGQDFLALVDYAHKPGALRAVLSSLKRPDRRLAVVFGAGGERDPGKRAPMGATAA 418 Query: 424 ELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDV 483 ELADLVVVTDDNPRGEDPAAIRR+IL EIGDRRAAI++AVAWAGP DV Sbjct: 419 ELADLVVVTDDNPRGEDPAAIRREILAGATESGCAAEVIEIGDRRAAIRHAVAWAGPGDV 478 Query: 484 VLVAGKGHETGQRGAAETCPFDDRVELARALQ 515 VLVAGKGHETGQR T PFDDRVELA AL+ Sbjct: 479 VLVAGKGHETGQRTGEHTRPFDDRVELAEALR 510 >sp|P65477|MURE_MYCTU Tax_Id=1773 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium tuberculosis] Length = 535 Score = 636 bits (1640), Expect = e-180 Identities = 336/519 (64%), Positives = 373/519 (71%), Gaps = 1/519 (0%) Query: 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct: 17 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 76 Query: 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct: 77 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 135 Query: 122 AAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLT 181 A YGHPS R+ E TIGIR+ GAD+PS LT Sbjct: 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 Query: 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct: 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 Query: 242 EEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRS 301 +YFEAKA LFDP S LRART VVC VSA +PA WRATD+ Sbjct: 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 315 Query: 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct: 316 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 375 Query: 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct: 376 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 435 Query: 422 AAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 AA+LADLVVVTDDNPR EDP AIRR+IL EI DRR AI++AVAWA P Sbjct: 436 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 495 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct: 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 534 >sp|P65478|MURE_MYCBO Tax_Id=1765 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium bovis] Length = 535 Score = 636 bits (1640), Expect = e-180 Identities = 336/519 (64%), Positives = 373/519 (71%), Gaps = 1/519 (0%) Query: 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct: 17 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 76 Query: 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct: 77 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 135 Query: 122 AAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLT 181 A YGHPS R+ E TIGIR+ GAD+PS LT Sbjct: 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 Query: 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct: 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 Query: 242 EEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRS 301 +YFEAKA LFDP S LRART VVC VSA +PA WRATD+ Sbjct: 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 315 Query: 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct: 316 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 375 Query: 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct: 376 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 435 Query: 422 AAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 AA+LADLVVVTDDNPR EDP AIRR+IL EI DRR AI++AVAWA P Sbjct: 436 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 495 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct: 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 534 >tr|C6DPQ0|C6DPQ0_MYCTK Tax_Id=478434 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelat E ligase MurE;[Mycobacterium tuberculosis] Length = 535 Score = 636 bits (1640), Expect = e-180 Identities = 336/519 (64%), Positives = 373/519 (71%), Gaps = 1/519 (0%) Query: 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct: 17 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 76 Query: 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct: 77 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 135 Query: 122 AAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLT 181 A YGHPS R+ E TIGIR+ GAD+PS LT Sbjct: 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 Query: 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct: 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 Query: 242 EEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRS 301 +YFEAKA LFDP S LRART VVC VSA +PA WRATD+ Sbjct: 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 315 Query: 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct: 316 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 375 Query: 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct: 376 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 435 Query: 422 AAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 AA+LADLVVVTDDNPR EDP AIRR+IL EI DRR AI++AVAWA P Sbjct: 436 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 495 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct: 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 534 >tr|C1AQ74|C1AQ74_MYCBT Tax_Id=561275 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; EC=6.3.2.13;[Mycobacterium bovis] Length = 535 Score = 636 bits (1640), Expect = e-180 Identities = 336/519 (64%), Positives = 373/519 (71%), Gaps = 1/519 (0%) Query: 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct: 17 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 76 Query: 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct: 77 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 135 Query: 122 AAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLT 181 A YGHPS R+ E TIGIR+ GAD+PS LT Sbjct: 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 Query: 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct: 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 Query: 242 EEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRS 301 +YFEAKA LFDP S LRART VVC VSA +PA WRATD+ Sbjct: 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 315 Query: 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct: 316 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 375 Query: 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct: 376 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 435 Query: 422 AAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 AA+LADLVVVTDDNPR EDP AIRR+IL EI DRR AI++AVAWA P Sbjct: 436 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 495 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct: 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 534 >tr|A5U4I5|A5U4I5_MYCTA Tax_Id=419947 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate MurE;[Mycobacterium tuberculosis] Length = 535 Score = 636 bits (1640), Expect = e-180 Identities = 336/519 (64%), Positives = 373/519 (71%), Gaps = 1/519 (0%) Query: 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct: 17 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 76 Query: 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct: 77 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 135 Query: 122 AAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLT 181 A YGHPS R+ E TIGIR+ GAD+PS LT Sbjct: 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 Query: 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct: 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 Query: 242 EEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRS 301 +YFEAKA LFDP S LRART VVC VSA +PA WRATD+ Sbjct: 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 315 Query: 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct: 316 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 375 Query: 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct: 376 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 435 Query: 422 AAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 AA+LADLVVVTDDNPR EDP AIRR+IL EI DRR AI++AVAWA P Sbjct: 436 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 495 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct: 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 534 >tr|A1KKK1|A1KKK1_MYCBP Tax_Id=410289 (murE)SubName: Full=Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase MurE; EC=6.3.2.13;[Mycobacterium bovis] Length = 535 Score = 636 bits (1640), Expect = e-180 Identities = 336/519 (64%), Positives = 373/519 (71%), Gaps = 1/519 (0%) Query: 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct: 17 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 76 Query: 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct: 77 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 135 Query: 122 AAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLT 181 A YGHPS R+ E TIGIR+ GAD+PS LT Sbjct: 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 Query: 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct: 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 Query: 242 EEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRS 301 +YFEAKA LFDP S LRART VVC VSA +PA WRATD+ Sbjct: 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 315 Query: 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct: 316 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 375 Query: 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct: 376 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 435 Query: 422 AAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 AA+LADLVVVTDDNPR EDP AIRR+IL EI DRR AI++AVAWA P Sbjct: 436 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 495 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct: 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 534 >tr|A5WPD0|A5WPD0_MYCTF Tax_Id=336982 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelat E ligase murE;[Mycobacterium tuberculosis] Length = 535 Score = 636 bits (1640), Expect = e-180 Identities = 336/519 (64%), Positives = 373/519 (71%), Gaps = 1/519 (0%) Query: 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct: 17 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 76 Query: 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct: 77 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 135 Query: 122 AAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLT 181 A YGHPS R+ E TIGIR+ GAD+PS LT Sbjct: 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 Query: 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct: 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 Query: 242 EEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRS 301 +YFEAKA LFDP S LRART VVC VSA +PA WRATD+ Sbjct: 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 315 Query: 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct: 316 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 375 Query: 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct: 376 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 435 Query: 422 AAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 AA+LADLVVVTDDNPR EDP AIRR+IL EI DRR AI++AVAWA P Sbjct: 436 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 495 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct: 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 534 >tr|A2VJQ4|A2VJQ4_MYCTU Tax_Id=348776 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelat E ligase murE;[Mycobacterium tuberculosis C] Length = 521 Score = 636 bits (1640), Expect = e-180 Identities = 336/519 (64%), Positives = 373/519 (71%), Gaps = 1/519 (0%) Query: 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct: 3 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 62 Query: 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct: 63 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 121 Query: 122 AAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLT 181 A YGHPS R+ E TIGIR+ GAD+PS LT Sbjct: 122 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 181 Query: 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct: 182 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 241 Query: 242 EEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRS 301 +YFEAKA LFDP S LRART VVC VSA +PA WRATD+ Sbjct: 242 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 301 Query: 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct: 302 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 361 Query: 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct: 362 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 421 Query: 422 AAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 AA+LADLVVVTDDNPR EDP AIRR+IL EI DRR AI++AVAWA P Sbjct: 422 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 481 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct: 482 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 520 >tr|B2HGS1|B2HGS1_MYCMM Tax_Id=216594 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase MurE;[Mycobacterium marinum] Length = 521 Score = 626 bits (1614), Expect = e-177 Identities = 334/512 (65%), Positives = 370/512 (72%), Gaps = 3/512 (0%) Query: 11 LRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGAS 70 LRPSA GV L EL QVGAVLADGP +AA VPD +TG+TLRAQ V GDLFAALAG++ Sbjct: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 Query: 71 THGARYAGVALERGAVAVLTDVAGVAELTAQA---SSVPILIHPEPRSVLGGLAAAAYGH 127 THGAR+A A+ERGAVAVLTD AGV ++A +VP+L+HP PR VLG AA YGH Sbjct: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 Query: 128 PSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPA 187 PS+R+ E TIGIRIDGADIPS LTTPEAPA Sbjct: 128 PSDRLTVVGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRIDGADIPSTLTTPEAPA 187 Query: 188 LQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEA 247 LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+G +FAV GFTNLSRDHLDFHP M +YFEA Sbjct: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 Query: 248 KAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQ 307 KA+LFDP S LR +VVVC VSA GQPA WRATD+ G G Q Sbjct: 248 KALLFDPASALRGHSVVVCIDDEAGRAMADRAGAAITVSATGQPAHWRATDVAPVGAGGQ 307 Query: 308 EFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERI 367 EFTA+DPAGV HRV I LPG YNVANCL+ALAILD VGVSPEQA+ G R+ R+PGRLE++ Sbjct: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 Query: 368 DCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAELAD 427 D GQDFLALVDYAHKPGAL VL+ L P RLAVVFGAGG+RDPGKR PMG IAAELAD Sbjct: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 Query: 428 LVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVA 487 LVVVTDDNPRGEDP AIRR I+ EI DR AI YAV WA DVVL+A Sbjct: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 Query: 488 GKGHETGQRGAAETCPFDDRVELARALQVRDA 519 GKGHETGQRG AE PFDDRVELARAL+ ++ Sbjct: 488 GKGHETGQRGGAEVRPFDDRVELARALEALES 519 >tr|A0PTJ2|A0PTJ2_MYCUA Tax_Id=362242 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase MurE;[Mycobacterium ulcerans] Length = 559 Score = 621 bits (1602), Expect = e-176 Identities = 335/522 (64%), Positives = 373/522 (71%), Gaps = 4/522 (0%) Query: 2 TEVVA-VPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSG 60 TEVV+ V LRPSA GV L EL QVGAVLADGP +AA VPD +TG+TLRAQ V G Sbjct: 36 TEVVSEVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPG 95 Query: 61 DLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQA---SSVPILIHPEPRSVL 117 DLFAALAG++THGAR+ A+ERGAVAVLTD AGV ++A +VP+L+HP PR VL Sbjct: 96 DLFAALAGSATHGARHTADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVL 155 Query: 118 GGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIP 177 G AA YGHPS+R+ E TIGIRIDGADIP Sbjct: 156 GEAAALVYGHPSDRLTVVGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRIDGADIP 215 Query: 178 SFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDF 237 S LTTPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+G +FAV GFTNLSRDHLDF Sbjct: 216 STLTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDF 275 Query: 238 HPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRAT 297 HP M +YFEAKA+LFDP S LR +VVVC VSA GQPA WRAT Sbjct: 276 HPTMADYFEAKALLFDPASALRGHSVVVCIDDEAGRAMADRAGVAITVSATGQPAHWRAT 335 Query: 298 DIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRD 357 D+ G G QEFTA+DPAGV HRV I PG YNV+NCL+ALAILD VGVSPEQA+ G R+ Sbjct: 336 DVAPVGAGGQEFTALDPAGVGHRVRIGSPGHYNVSNCLLALAILDAVGVSPEQAAPGLRE 395 Query: 358 IRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAP 417 R+PGRLE++D GQDFLALVDYAHKPGAL VL+ L P RLAVVFGAGG+RDPGKR P Sbjct: 396 TRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGP 455 Query: 418 MGEIAAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAW 477 MG IAAELADLVVVTDDNPRGEDP AIRR I+ EI DR AI YAV W Sbjct: 456 MGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDW 515 Query: 478 AGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDA 519 A DVVL+AGKGHETGQRG AE PFDDRVELARAL+ ++ Sbjct: 516 ARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALES 557 >tr|Q1B6W6|Q1B6W6_MYCSS Tax_Id=164756 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Mycobacterium sp.] Length = 508 Score = 542 bits (1397), Expect = e-152 Identities = 299/510 (58%), Positives = 336/510 (65%), Gaps = 6/510 (1%) Query: 9 VRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAG 68 ++LRPS G L L QV AV A G VPDI VTGVTLR Q+ L GDLFAAL G Sbjct: 3 MKLRPSHPVGHALGALAEQVQAVPAPG----FPVPDIRVTGVTLRGQDALPGDLFAALPG 58 Query: 69 ASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHP 128 +S HGAR+ A+ GAVAVLTD AG L A VP+L+HP+PR+VLG +A+ YGHP Sbjct: 59 SSAHGARFVADAVAAGAVAVLTDAAGAVMLGADPV-VPVLVHPDPRAVLGAVASTVYGHP 117 Query: 129 SNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPAL 188 S + E T+GIRIDG D PS LTTPEAP L Sbjct: 118 SQHLRVVGVTGTSGKTTTTYLVEAGLRAAGRVAGLIGTVGIRIDGRDQPSALTTPEAPDL 177 Query: 189 QAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAK 248 QA+LA MVE+GV+TVVMEVSSHAL+LGRV+G FA GFTNLSRDHLDFHP ME+YF+AK Sbjct: 178 QALLAVMVEQGVDTVVMEVSSHALTLGRVDGVHFAAGGFTNLSRDHLDFHPTMEDYFDAK 237 Query: 249 AVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQE 308 A LFDP S RA VVC VSA G+PA WRA D+R+ GAQE Sbjct: 238 AGLFDPQSRTRAELAVVCVDDDAGRAMAIRAGRAVTVSASGRPADWRAEDVRAVEAGAQE 297 Query: 309 FTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERID 368 F AVDPAGV H + I LPG YNVANC++A A+LD V VSPEQA+ G R +PGRLE +D Sbjct: 298 FVAVDPAGVHHGLRIALPGHYNVANCVLAAALLDAVDVSPEQAAPGLRTATVPGRLEAVD 357 Query: 369 CGQDFLALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMGEIAAELAD 427 GQDFLALVDYAHKPGAL +VL L Q R+AVVFGAGG RD GKR PMG +AAELAD Sbjct: 358 RGQDFLALVDYAHKPGALRAVLETLRGQGKGRIAVVFGAGGNRDAGKREPMGRVAAELAD 417 Query: 428 LVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVA 487 LVVVTDDNPR EDPA IR I+ EIGDRR AI +AV WA P DVVLVA Sbjct: 418 LVVVTDDNPRDEDPATIRAAIMAGARAAGGGADVVEIGDRREAIAHAVRWARPGDVVLVA 477 Query: 488 GKGHETGQRGAAETCPFDDRVELARALQVR 517 GKGHETGQ A T PFDDRVELA L+ R Sbjct: 478 GKGHETGQTAAGRTHPFDDRVELAELLEKR 507 >tr|A1UI59|A1UI59_MYCSK Tax_Id=189918 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Mycobacterium sp.] Length = 508 Score = 542 bits (1397), Expect = e-152 Identities = 299/510 (58%), Positives = 336/510 (65%), Gaps = 6/510 (1%) Query: 9 VRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAG 68 ++LRPS G L L QV AV A G VPDI VTGVTLR Q+ L GDLFAAL G Sbjct: 3 MKLRPSHPVGHALGALAEQVQAVPAPG----FPVPDIRVTGVTLRGQDALPGDLFAALPG 58 Query: 69 ASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHP 128 +S HGAR+ A+ GAVAVLTD AG L A VP+L+HP+PR+VLG +A+ YGHP Sbjct: 59 SSAHGARFVADAVAAGAVAVLTDAAGAVMLGADPV-VPVLVHPDPRAVLGAVASTVYGHP 117 Query: 129 SNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPAL 188 S + E T+GIRIDG D PS LTTPEAP L Sbjct: 118 SQHLRVVGVTGTSGKTTTTYLVEAGLRAAGRVAGLIGTVGIRIDGRDQPSALTTPEAPDL 177 Query: 189 QAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAK 248 QA+LA MVE+GV+TVVMEVSSHAL+LGRV+G FA GFTNLSRDHLDFHP ME+YF+AK Sbjct: 178 QALLAVMVEQGVDTVVMEVSSHALTLGRVDGVHFAAGGFTNLSRDHLDFHPTMEDYFDAK 237 Query: 249 AVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQE 308 A LFDP S RA VVC VSA G+PA WRA D+R+ GAQE Sbjct: 238 AGLFDPQSRTRAELAVVCVDDDAGRAMAIRAGRAVTVSASGRPADWRAEDVRAVEAGAQE 297 Query: 309 FTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERID 368 F AVDPAGV H + I LPG YNVANC++A A+LD V VSPEQA+ G R +PGRLE +D Sbjct: 298 FVAVDPAGVHHGLRIALPGHYNVANCVLAAALLDAVDVSPEQAAPGLRTATVPGRLEAVD 357 Query: 369 CGQDFLALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMGEIAAELAD 427 GQDFLALVDYAHKPGAL +VL L Q R+AVVFGAGG RD GKR PMG +AAELAD Sbjct: 358 RGQDFLALVDYAHKPGALRAVLETLRGQGKGRIAVVFGAGGNRDAGKREPMGRVAAELAD 417 Query: 428 LVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVA 487 LVVVTDDNPR EDPA IR I+ EIGDRR AI +AV WA P DVVLVA Sbjct: 418 LVVVTDDNPRDEDPATIRAAIMAGARAAGGGADVVEIGDRREAIAHAVRWARPGDVVLVA 477 Query: 488 GKGHETGQRGAAETCPFDDRVELARALQVR 517 GKGHETGQ A T PFDDRVELA L+ R Sbjct: 478 GKGHETGQTAAGRTHPFDDRVELAELLEKR 507 >tr|A3Q1M3|A3Q1M3_MYCSJ Tax_Id=164757 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetases;[Mycobacterium sp.] Length = 508 Score = 540 bits (1391), Expect = e-151 Identities = 298/510 (58%), Positives = 335/510 (65%), Gaps = 6/510 (1%) Query: 9 VRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAG 68 ++LRPS G L L QV AV A G VPDI VTGVTLR Q+ L GDLFAAL G Sbjct: 3 MKLRPSHPVGHALGALAEQVQAVPAPG----FPVPDIRVTGVTLRGQDALPGDLFAALPG 58 Query: 69 ASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHP 128 +S HGAR+ A+ GAVAVLTD AG L A VP+L+HP+PR+VLG +A+ YGHP Sbjct: 59 SSAHGARFVADAVAAGAVAVLTDAAGAVMLGADPV-VPVLVHPDPRAVLGAVASTVYGHP 117 Query: 129 SNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPAL 188 S + E T+GIRIDG D PS LTTPEAP L Sbjct: 118 SQHLRVVGVTGTSGKTTTTYLVEAGLRAAGRVAGLIGTVGIRIDGRDQPSALTTPEAPDL 177 Query: 189 QAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAK 248 QA+LA MVE+GV+TVVMEVSSHAL+LGRV+G FA GFTNLSRDHLDFHP ME+YF+AK Sbjct: 178 QALLAVMVEQGVDTVVMEVSSHALTLGRVDGVHFAAGGFTNLSRDHLDFHPTMEDYFDAK 237 Query: 249 AVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQE 308 A LFDP S RA VVC VSA G+PA WRA D+R+ GAQE Sbjct: 238 AGLFDPQSRTRAELAVVCVDDDAGRAMAIRAGRAVTVSASGRPADWRAEDVRAVEAGAQE 297 Query: 309 FTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERID 368 F AVDPAGV H + I LPG YNVANCL+A A+LD V VSPEQA+ G R +PGRLE +D Sbjct: 298 FVAVDPAGVHHGLRIALPGHYNVANCLLAAALLDAVDVSPEQAAPGLRTATVPGRLEAVD 357 Query: 369 CGQDFLALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMGEIAAELAD 427 GQDFLALVDYAHKPGAL +VL L Q R+AVVFGAGG RD GKR PMG +AAELAD Sbjct: 358 RGQDFLALVDYAHKPGALRAVLETLRGQGTGRIAVVFGAGGNRDAGKREPMGRVAAELAD 417 Query: 428 LVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVA 487 LVVVTDDNPR EDPA IR I+ E+GDRR AI +AV WA DVVLVA Sbjct: 418 LVVVTDDNPRDEDPATIRAAIMAGARAAGGGADVVEVGDRREAIAHAVRWARSGDVVLVA 477 Query: 488 GKGHETGQRGAAETCPFDDRVELARALQVR 517 GKGHETGQ A T PFDDRVELA L+ R Sbjct: 478 GKGHETGQTAAGRTHPFDDRVELAELLEKR 507 >tr|A0R021|A0R021_MYCS2 Tax_Id=246196 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase;[Mycobacterium smegmatis] Length = 520 Score = 534 bits (1375), Expect = e-149 Identities = 290/509 (56%), Positives = 336/509 (66%), Gaps = 3/509 (0%) Query: 9 VRLRPSATAGVRLPELVAQVGAVLADGP-GQAATVPDIPVTGVTLRAQEVLSGDLFAALA 67 ++LRPS G L L A VGAV ++ P G ++ + + VTGVTLR Q+ GDLFAAL Sbjct: 3 MKLRPSRPVGHHLAPLAAAVGAVASENPAGSSSDLAAVHVTGVTLRGQDAQPGDLFAALP 62 Query: 68 GASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGH 127 GAS HGAR+A A+ GAVAVLTD +G A+L A VP+L+HP PRSVLG AA YG Sbjct: 63 GASAHGARFAADAVAAGAVAVLTDPSG-ADLLAGTLDVPVLVHPAPRSVLGEAAAIVYGR 121 Query: 128 PSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPA 187 P+ R+ E T+G+RIDG D+PS LTTPEAPA Sbjct: 122 PAERLRVVGVTGTSGKTTTTYLAEAGLRAAGRVAGLIGTVGVRIDGTDLPSALTTPEAPA 181 Query: 188 LQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEA 247 LQA+LA MVERGV+TVVMEVSSHAL+ GRV+G FAV GFTNLSRDHLDFHP M +YFEA Sbjct: 182 LQALLALMVERGVDTVVMEVSSHALAQGRVDGIGFAVGGFTNLSRDHLDFHPTMADYFEA 241 Query: 248 KAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQ 307 KA LFDP S A V+C VS G A WR I + G GAQ Sbjct: 242 KARLFDPQSPNHAAAAVICVDDQYGVQMAARAETPLTVSTSGAAADWRVEKITTAGPGAQ 301 Query: 308 EFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERI 367 EF VDP G+ H++G+ LPGRYNVAN +A+A+LD VGVSPEQA+ G R +PGRLE I Sbjct: 302 EFVLVDPGGMHHQLGVGLPGRYNVANAALAVALLDAVGVSPEQAAPGLRTATVPGRLESI 361 Query: 368 DCGQDFLALVDYAHKPGALHSVLTALLQPD-HRLAVVFGAGGERDPGKRAPMGEIAAELA 426 D GQDFLALVDYAHKPGAL +VL L + R+AVVFGAGG+RDPGKR PMG + AELA Sbjct: 362 DLGQDFLALVDYAHKPGALQAVLETLRAAEPRRIAVVFGAGGDRDPGKREPMGRVTAELA 421 Query: 427 DLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLV 486 DLVVVTDDNPR EDPA IR IL EIGDRRAAI +AVAWA P D+VL+ Sbjct: 422 DLVVVTDDNPRSEDPATIRSAILAGARAVASDAEIVEIGDRRAAIDHAVAWAQPGDIVLI 481 Query: 487 AGKGHETGQRGAAETCPFDDRVELARALQ 515 AGKGHE+GQ T PFDDR ELA AL+ Sbjct: 482 AGKGHESGQTVGDHTRPFDDRDELAAALE 510 >tr|A1TAX3|A1TAX3_MYCVP Tax_Id=350058 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Mycobacterium vanbaalenii] Length = 497 Score = 518 bits (1334), Expect = e-145 Identities = 286/499 (57%), Positives = 330/499 (66%), Gaps = 8/499 (1%) Query: 24 LVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALER 83 ++A + A +A G G A PD+ VTGVTLR Q+ GDLFAAL G+ HG RYA A+ R Sbjct: 1 MLADLVAAVAAGGGGA---PDVQVTGVTLRGQDAQPGDLFAALPGSRAHGGRYAAEAVGR 57 Query: 84 GAVAVLTDVAGVAELTAQ-ASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXX 142 GAVAVLTD AG AE+ ++ A VP+L+HP+PR+VLG LA+A YG PS + Sbjct: 58 GAVAVLTDAAGEAEIASRGAPDVPVLVHPDPRAVLGELASAVYGRPSQHLRVIGVTGTSG 117 Query: 143 XXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVET 202 E T+G+RIDG P LTTPEAP LQA+LA M+E+GV+T Sbjct: 118 KTTTTYLVEAGLRAAGRVAGLIGTVGVRIDGRQQPGGLTTPEAPELQALLATMLEQGVDT 177 Query: 203 VVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRART 262 VVMEVSSHAL+LGRV+G FAV GFTNLSRDHLDFHP ME+YF+AKA LFDP A Sbjct: 178 VVMEVSSHALTLGRVDGVSFAVGGFTNLSRDHLDFHPTMEDYFDAKARLFDPACATHAAR 237 Query: 263 VVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVG 322 V+C VS G PA WRA +RS G GAQ+F AVDPAGV H + Sbjct: 238 SVICVDDEWGRAMAARARRPVTVSTTG-PADWRAEQVRSAGGGAQDFVAVDPAGVHHGLE 296 Query: 323 IRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHK 382 I LPG YNVANCL+A+A+LD VGVSPEQA+ G RD +PGRLE +D GQ FLALVDYAHK Sbjct: 297 IGLPGGYNVANCLLAIALLDAVGVSPEQAAPGVRDATVPGRLESVDRGQPFLALVDYAHK 356 Query: 383 PGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDP 441 PGAL +VL L Q RLAVVFGAGG RD GKR PMG +AAELADLVVVTDDNPR EDP Sbjct: 357 PGALRAVLQTLREQCTGRLAVVFGAGGNRDQGKREPMGRVAAELADLVVVTDDNPRDEDP 416 Query: 442 AAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAET 501 A IR IL EIGDRRAAI +A WA D+VL+AGKGHE GQ +T Sbjct: 417 AVIRAAIL--AGAAGARAEVVEIGDRRAAIGHAAGWARAGDIVLIAGKGHEAGQTSGGQT 474 Query: 502 CPFDDRVELARALQVRDAR 520 PFDDR ELA AL+ R AR Sbjct: 475 RPFDDRDELAAALEARGAR 493 >tr|A4TBF0|A4TBF0_MYCGI Tax_Id=350054 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; Flags: Precursor;[Mycobacterium gilvum] Length = 512 Score = 506 bits (1304), Expect = e-141 Identities = 288/509 (56%), Positives = 330/509 (64%), Gaps = 11/509 (2%) Query: 9 VRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAG 68 + LRPS G+ L L V A AD A VPD+ VTGVTLR Q +GDLFAAL G Sbjct: 1 MNLRPSHPVGMPLGALADLVCAEPAD----AGPVPDLQVTGVTLRGQHAQAGDLFAALPG 56 Query: 69 ASTHGARYAGVALERGAVAVLTDVAGVAELTAQAS-SVPILIHPEPRSVLGGLAAAAYGH 127 + HGARYA A+ERGAVAVLTD GV+E+ A +VPIL+HP PRSVLG +AAA +G Sbjct: 57 SKAHGARYAADAVERGAVAVLTDADGVSEIAAHGGPAVPILVHPAPRSVLGEVAAAVFGR 116 Query: 128 PSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPA 187 PS + E T+G+RIDG P LTTPEAP Sbjct: 117 PSEHLRVIGVTGTSGKTTTTYLVEAGLRSAGRVAGLIGTVGVRIDGRAQPGGLTTPEAPD 176 Query: 188 LQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEA 247 LQA+LAAM+E+GV+TVVMEVSSHAL+LGRV+G FAV GFTNLSRDHLDFHP M++YFEA Sbjct: 177 LQALLAAMLEQGVDTVVMEVSSHALTLGRVDGVSFAVGGFTNLSRDHLDFHPTMQDYFEA 236 Query: 248 KAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQ 307 KA L DP S A V+C VS G A W ++R+ G Q Sbjct: 237 KARLVDPTSPTHAARSVICVDDEWGRAMAARADAPVTVSVTGD-ADWWVQEVRALDGGVQ 295 Query: 308 EFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERI 367 +F AVDPAGV H + I LPG YNVANCL+A+A+LD V VSPEQA+ G RD +PGRLE + Sbjct: 296 DFLAVDPAGVHHALEIGLPGGYNVANCLLAVALLDAVDVSPEQAAPGLRDATVPGRLEAV 355 Query: 368 DCGQDFLALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMGEIAAELA 426 D GQ FLALVDYAHKPGAL +VL L Q RLAVVFGAGG+RD GKR PMG +AAELA Sbjct: 356 DRGQPFLALVDYAHKPGALAAVLQTLREQCAGRLAVVFGAGGDRDQGKREPMGRVAAELA 415 Query: 427 DLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLV 486 DLVVVTDDNPRGEDPA IR IL EIGDRRAAI +AV WA D+VL+ Sbjct: 416 DLVVVTDDNPRGEDPAVIRAAIL----RGASGAQTVEIGDRRAAIVHAVQWAREGDIVLI 471 Query: 487 AGKGHETGQRGAAETCPFDDRVELARALQ 515 AGKGHE GQ T PFDDR ELA AL+ Sbjct: 472 AGKGHEAGQTSQGRTRPFDDRDELAAALE 500 >tr|B1MP32|B1MP32_MYCA9 Tax_Id=561007 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase MurE;[Mycobacterium abscessus] Length = 515 Score = 452 bits (1163), Expect = e-125 Identities = 262/491 (53%), Positives = 308/491 (62%), Gaps = 13/491 (2%) Query: 31 VLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLT 90 V A+ G +AT V GVTLRAQ+ +GDLFAAL G STHGA++A A+ GA AVLT Sbjct: 25 VSAELHGPSATT----VGGVTLRAQDARTGDLFAALPGTSTHGAQFASEAVSAGAAAVLT 80 Query: 91 DVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXX 150 D AG + Q + +L+HP PRSVLG LAA YG PS + Sbjct: 81 DAAGAELVAGQGLDIAVLVHPVPRSVLGELAATVYGEPSRHLQVVGVTGTSGKTTTTYLV 140 Query: 151 EXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSH 210 E T+G+RIDG D+PS LTTPEAPALQ +LA MV+RGV+TVVMEVSSH Sbjct: 141 EAGLRAAGKRVGLIGTVGVRIDGEDVPSALTTPEAPALQELLAEMVQRGVDTVVMEVSSH 200 Query: 211 ALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVC---- 266 AL+L RV+GT+FAV FTNLSRDHLDFHPDM++YF KA LF S RA VVC Sbjct: 201 ALALNRVDGTRFAVGAFTNLSRDHLDFHPDMQDYFATKARLFRRDSPQRAHRSVVCIDDD 260 Query: 267 XXXXXXXXXXXXXXXXXXVSAL-GQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRL 325 VS+L G A WR +++ G Q F A P + I L Sbjct: 261 AGRAMAELAREAGPDVTTVSSLDGGVADWRCSNVAVGHDGGQRFVANGP-DRDTELTIAL 319 Query: 326 PGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGA 385 PG YNVANCLVA+AILDV+GVS A+ G +PGR+E + GQ FLA+VDYAHKPGA Sbjct: 320 PGHYNVANCLVAIAILDVLGVSAATAAPGIATAGVPGRMEAVAAGQPFLAVVDYAHKPGA 379 Query: 386 LHSVLTAL-LQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAI 444 L +VL +L D RLAVVFGAGG RD GKRA MG++AAELADLVVVTDDNPR E+PAAI Sbjct: 380 LRAVLESLRSHRDGRLAVVFGAGGNRDRGKRADMGKVAAELADLVVVTDDNPRNEEPAAI 439 Query: 445 RRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPF 504 R +I+ EIGDRRAAI +A WA P D VLVAGKGHE+GQ+ T PF Sbjct: 440 RTEII--SGTTGSEAQIIEIGDRRAAIDFATLWARPGDTVLVAGKGHESGQKTGDVTVPF 497 Query: 505 DDRVELARALQ 515 DDRVEL AL+ Sbjct: 498 DDRVELRAALE 508 >tr|Q5YYY4|Q5YYY4_NOCFA Tax_Id=37329 (murE)SubName: Full=Putative UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase;[Nocardia farcinica] Length = 536 Score = 403 bits (1035), Expect = e-110 Identities = 244/491 (49%), Positives = 287/491 (58%), Gaps = 15/491 (3%) Query: 35 GPGQAATVP-DIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVA 93 G AA VP D+ VTG+ R+ V GDLFAAL GA HGAR+A A+ RGAVAV TD Sbjct: 40 GAHAAAPVPADVVVTGIEQRSGAVQPGDLFAALPGAHAHGARFAHDAVARGAVAVFTDAE 99 Query: 94 GVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXX 153 G L +VP+L+ PR VLG L+AA YG PS R+ E Sbjct: 100 GARVL--DGLTVPVLVRERPREVLGELSAAVYGQPSQRLRLIGITGTSGKTTTSYLVEAG 157 Query: 154 XXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALS 213 TI RI G +PS LTTPEAP L AM A MVE+GV+ VVMEVSSHAL+ Sbjct: 158 LAAAGLSTALIGTIETRIGGRRVPSALTTPEAPQLHAMFALMVEQGVQAVVMEVSSHALA 217 Query: 214 LGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXX 273 LGRV+G +F V FTNLS+DHLDFH D E+YF AK LF+P S + ART VVC Sbjct: 218 LGRVDGVRFDVGAFTNLSQDHLDFHADFEDYFAAKRRLFEPQSPVAARTAVVCVDDAWGR 277 Query: 274 XXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVAN 333 VS G+ A WR + QEFTA PAG + V +RLPGRYNVAN Sbjct: 278 RLAEGLAAPITVSTTGE-ADWRVAGGVATVGAEQEFTAAGPAG-ELGVRLRLPGRYNVAN 335 Query: 334 CLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTAL 393 L+A+A+ P A+ + +PGR++R++ GQDFLA+VDYAHKP AL SV+ L Sbjct: 336 ALLAVAVCAAARADPAVAAPALATVDVPGRMQRVERGQDFLAVVDYAHKPAALESVIATL 395 Query: 394 LQ------PDH--RLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIR 445 + P+H RLAVV GAGG+RD GKRA MG A ADL+V+TDDNPR EDPA IR Sbjct: 396 REHLAAADPEHPGRLAVVVGAGGDRDAGKRALMGAAGARGADLLVITDDNPRTEDPATIR 455 Query: 446 RDIL--XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCP 503 + EIGDR AAI+ AVAWA D VLVAGKGHETGQ A P Sbjct: 456 AALRAGALEVPAEVRGEVREIGDRAAAIEAAVAWARRGDAVLVAGKGHETGQEIAGVKHP 515 Query: 504 FDDRVELARAL 514 FDDR LA AL Sbjct: 516 FDDREVLAAAL 526 >tr|C3JJ53|C3JJ53_RHOER Tax_Id=596309 SubName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Rhodococcus erythropolis SK121] Length = 544 Score = 402 bits (1034), Expect = e-110 Identities = 243/517 (47%), Positives = 296/517 (57%), Gaps = 19/517 (3%) Query: 12 RPSATAGVRLPELVAQVGAVL--ADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGA 69 +P ATA L EL GA L PG ++ ++ V GV LRAQ +++ DLFAAL GA Sbjct: 20 QPVATAITALSELS---GARLEWVGLPGSQSS--EVVVKGVDLRAQGIVTDDLFAALPGA 74 Query: 70 STHGARYAGVALERGAVAVLTDVAGVAELTAQAS----SVPILIHPEPRSVLGGLAAAAY 125 THGA++A AL RGA A+LTD AG+ + A SVP+L+HP PR VLG ++A Y Sbjct: 75 RTHGAQFAVDALGRGATAILTDEAGLELIEAADKAPDRSVPVLVHPNPRDVLGEISAEIY 134 Query: 126 GHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEA 185 G PS +M E TI RIDG +PS LTTPEA Sbjct: 135 GRPSEKMQVVGITGTSGKTTTSYLLEAAIAGAGRKPGLVGTIETRIDGRRVPSALTTPEA 194 Query: 186 PALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYF 245 P L A+ A M E+G++TVVMEVSSHAL+LGRV+G +F + FTNLS+DHLDFH D EEYF Sbjct: 195 PQLHALFAVMAEQGIDTVVMEVSSHALALGRVDGIRFDIGAFTNLSQDHLDFHRDFEEYF 254 Query: 246 EAKAVLFDPHSLLRARTVVVC-----XXXXXXXXXXXXXXXXXXVSALGQPASWRATDIR 300 +AKA LFDP S +RA VVC VS A W + Sbjct: 255 QAKARLFDPESTVRAEHAVVCVDDVWGRRMAELAATDESDAVTTVSTSTAEAEWTVGAVE 314 Query: 301 SPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRI 360 G+Q F V P G V +RLPGRYNVAN +AL + G+ P+ A + + Sbjct: 315 VAEDGSQTFELVGPDGQSWPVSLRLPGRYNVANAALALTVSFAAGLDPDAAVRALGTVDV 374 Query: 361 PGRLERIDCGQDFLALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMG 419 PGR++RID GQ FLA+VDYAHKP AL +V+ L Q R+AVV GAGG+RD GKRA MG Sbjct: 375 PGRVQRIDRGQSFLAVVDYAHKPAALEAVIATLRNQVPGRVAVVVGAGGDRDAGKRALMG 434 Query: 420 EIAAELADLVVVTDDNPRGEDPAAIRRDIL--XXXXXXXXXXXXXEIGDRRAAIQYAVAW 477 E A ADL++VTDDNPR EDPA IR ++ E+GDR AAI+ AV W Sbjct: 435 EAGARGADLLIVTDDNPRTEDPAKIRASVMQGAMDVPESERGEVREVGDRAAAIEQAVRW 494 Query: 478 AGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARAL 514 A P DVVLVAGKGHE GQ PFDDR L + Sbjct: 495 AQPGDVVLVAGKGHEVGQEIDGVKHPFDDREVLGEMI 531 >tr|C1A0Y0|C1A0Y0_RHOE4 Tax_Id=234621 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Rhodococcus erythropolis] Length = 544 Score = 402 bits (1032), Expect = e-110 Identities = 241/517 (46%), Positives = 295/517 (57%), Gaps = 19/517 (3%) Query: 12 RPSATAGVRLPELVAQVGAVL--ADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGA 69 +P ATA L EL GA L PG ++ ++ V GV LRAQ +++ DLFAAL GA Sbjct: 20 QPVATAITALSELS---GARLEWVGQPGSQSS--EVVVKGVDLRAQGIVADDLFAALPGA 74 Query: 70 STHGARYAGVALERGAVAVLTDVAGVAELTAQAS----SVPILIHPEPRSVLGGLAAAAY 125 THGA++A AL RGA A+LTD AG+ + A SVP+L+HP PR VLG ++A Y Sbjct: 75 RTHGAQFAVDALGRGATAILTDEAGLELIEAAGKAPDRSVPVLVHPNPRDVLGEISAEIY 134 Query: 126 GHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEA 185 G PS +M E TI RIDG +PS LTTPEA Sbjct: 135 GRPSEKMQVVGITGTSGKTTTSYLLEAAIAGAGRKPGLVGTIETRIDGRRVPSALTTPEA 194 Query: 186 PALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYF 245 P L A+ A M E+G++TVVMEVSSHAL+LGRV+G +F + FTNLS+DHLDFH D EEYF Sbjct: 195 PQLHALFAVMAEQGIDTVVMEVSSHALALGRVDGIRFDIGAFTNLSQDHLDFHRDFEEYF 254 Query: 246 EAKAVLFDPHSLLRARTVVVC-----XXXXXXXXXXXXXXXXXXVSALGQPASWRATDIR 300 +AKA LFDP S +RA VVC VS A W+ + Sbjct: 255 QAKARLFDPESTVRAEHAVVCVDDVWGRRMAELAATDESDAVTTVSTSTAEAEWKVGAVE 314 Query: 301 SPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRI 360 G+Q F V P G V +RLPGRYNVAN +AL + G+ P+ A + + Sbjct: 315 VAEDGSQTFELVGPDGQSWPVSLRLPGRYNVANAALALTVSFAAGLDPDAAVRALGTVDV 374 Query: 361 PGRLERIDCGQDFLALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMG 419 PGR++RID GQ FLA+VDYAHKP AL +V+ L Q R+AVV GAGG+RD GKR MG Sbjct: 375 PGRVQRIDRGQSFLAVVDYAHKPAALEAVIATLRNQVPGRVAVVVGAGGDRDAGKRTLMG 434 Query: 420 EIAAELADLVVVTDDNPRGEDPAAIRRDIL--XXXXXXXXXXXXXEIGDRRAAIQYAVAW 477 E A ADL++VTDDNPR EDPA IR ++ E+GDR AI+ AV W Sbjct: 435 EAGARGADLLIVTDDNPRTEDPAKIRASVMQGAIDVPESERGEIREVGDRALAIEQAVRW 494 Query: 478 AGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARAL 514 A P DVVLVAGKGHE GQ PFDDR L + Sbjct: 495 AQPGDVVLVAGKGHEVGQEIDGVKHPFDDREVLGEMI 531 >tr|D0LAT6|D0LAT6_9ACTO Tax_Id=526226 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Gordonia bronchialis DSM 43247] Length = 556 Score = 399 bits (1025), Expect = e-109 Identities = 248/534 (46%), Positives = 302/534 (56%), Gaps = 33/534 (6%) Query: 7 VPVRLRPSATAGVRLPELVAQVGAVL-ADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAA 65 V LRP++ A + L GA L G ++AT VTGVTLRAQEV SGDLFAA Sbjct: 18 VSAALRPTSVAPTAVSVLSTSTGARLDLIGGAESAT----EVTGVTLRAQEVRSGDLFAA 73 Query: 66 LAGASTHGARYAGVALERGAVAVLTDVAGVAELTA---QASSVPILIHPEPRSVLGGLAA 122 L G++THGAR+A A+ GA A+LTD AG AEL+ +SV L+HPEPR+VLGG++A Sbjct: 74 LPGSTTHGARFAADAVAAGATAILTDPAGRAELSRVLPPEASVVALVHPEPRTVLGGVSA 133 Query: 123 AAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTT 182 YG+PS R+ E T+ RIDG PS LTT Sbjct: 134 RIYGNPSQRLKLIGITGTSGKTTTSYMVEAALLAAGSSVGLIGTVETRIDGVAQPSSLTT 193 Query: 183 PEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDME 242 PEAP LQA+LA M+ERGV+ VVMEVSSHAL+LGRV+G+ FA+ FTNLS+DHLDFHP M Sbjct: 194 PEAPTLQALLAVMLERGVDAVVMEVSSHALALGRVDGSHFALGAFTNLSQDHLDFHPTMA 253 Query: 243 EYFEAKAVLFDPHSLLRARTVVVC--------XXXXXXXXXXXXXXXXXXVSALGQPASW 294 YFEAKA LF P S + A V+C VS G PA W Sbjct: 254 AYFEAKAQLFVPSSPVHAVRSVICVDDEWGARMAELARPAARQSARQPVTVSTGGVPAQW 313 Query: 295 RATD--IRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQAS 352 A + + + G T D + + LPGRYNVAN L+A+A+ D GV A Sbjct: 314 HAAESVVDADGTSRTPITGTDG---DAELVVPLPGRYNVANALLAVAVADCAGVDAATAI 370 Query: 353 LGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTAL------LQPDHRLAVVFGA 406 + +PGRL+R+D GQ FLALVDYAHKPGA+ +VL L R+A+V GA Sbjct: 371 GAIATVSVPGRLQRVDRGQPFLALVDYAHKPGAVQAVLATLRAQAAARAEAGRVAIVIGA 430 Query: 407 GGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDIL------XXXXXXXXXXX 460 GG+RD KR MGE AA A+ VVVTDDNPR EDPAAIR ++L Sbjct: 431 GGDRDTAKRPLMGEAAARGAEFVVVTDDNPRTEDPAAIRAEVLAGARAVGRADRPAGAEE 490 Query: 461 XXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARAL 514 E+G R AI A+ WA P D VL+AGKGHETGQ PFDDR +A+ L Sbjct: 491 VREVGGRAEAIATALHWARPGDTVLIAGKGHETGQEINGVKHPFDDRDVVAQVL 544 >tr|C1AU60|C1AU60_RHOOB Tax_Id=632772 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Rhodococcus opacus] Length = 524 Score = 392 bits (1006), Expect = e-107 Identities = 232/514 (45%), Positives = 290/514 (56%), Gaps = 12/514 (2%) Query: 11 LRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGAS 70 LRP+ + L A GA + G T + VTGV LRAQ ++ GDLFAAL GA Sbjct: 7 LRPAQPVRTTVSALAALAGARVEAPSG---TAEHVIVTGVDLRAQGIVEGDLFAALPGAR 63 Query: 71 THGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSN 130 HGA +A AL+RGA A+LTD AG+A ++A + P+L+H +PR VLG L+A YG PS Sbjct: 64 AHGAEFAADALDRGATAILTDEAGLALVSALGTDAPVLVHDDPRGVLGELSATIYGRPSE 123 Query: 131 RMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQA 190 +M E TI R+ G +PS LTTPEAP L A Sbjct: 124 KMQVIGITGTSGKTTTSYLVEGALNAAGRTTGLVGTIETRMSGRRVPSALTTPEAPQLHA 183 Query: 191 MLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAV 250 + A M+E+G++TVVMEVSSHALSLGRV+G +F V FTNLS+DHLDFH D E+YF AKA Sbjct: 184 LFAVMLEQGIDTVVMEVSSHALSLGRVDGVRFDVGAFTNLSQDHLDFHRDFEDYFAAKAR 243 Query: 251 LFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXV--SALGQP----ASWRATDIRSPGV 304 LF S + A+ V+C + + P A W A Sbjct: 244 LFAAESSVHAQHAVICVDDVWGRRMAEVARGAHSIVTTVATTPETGGAVWTAGPATVSAS 303 Query: 305 GAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRL 364 G+Q+F G V +RLPG+YNVAN +A+A+ V+GV P A G + +PGR+ Sbjct: 304 GSQKFALTTAEGTTLDVELRLPGQYNVANASLAVALCAVLGVDPRDAVAGIAGVDVPGRV 363 Query: 365 ERIDCGQDFLALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMGEIAA 423 +RID GQDFLA+VDYAHKP A+ +V+ L Q R+AVV GAGG+RD GKR MG AA Sbjct: 364 QRIDRGQDFLAVVDYAHKPAAVEAVIATLREQARGRVAVVVGAGGDRDAGKRPLMGAAAA 423 Query: 424 ELADLVVVTDDNPRGEDPAAIRRDIL--XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPD 481 ADL+++TDDNPR EDPA IR I E+ DR AI AV WA Sbjct: 424 RGADLLIITDDNPRTEDPATIRAAIREGALGVPESERGQVWEVADRAKAIADAVGWAQAG 483 Query: 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQ 515 DVVLVAGKGHE GQ PFDDR L A++ Sbjct: 484 DVVLVAGKGHEIGQEIHGVKYPFDDRAVLGDAIE 517 >tr|C6WDE7|C6WDE7_ACTMD Tax_Id=446462 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Actinosynnema mirum] Length = 527 Score = 391 bits (1005), Expect = e-106 Identities = 237/507 (46%), Positives = 288/507 (56%), Gaps = 14/507 (2%) Query: 12 RPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGAST 71 RPS T V EL A V A L G + VTGVTLRAQ VL GDLFAAL GA Sbjct: 28 RPSRTQSVPASELAATVDARLTSPAGAP-----VLVTGVTLRAQHVLPGDLFAALPGARA 82 Query: 72 HGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNR 131 HGA +A A+ RGAVAVLTD G + + VP+L+H +PR+ LG L+A YG P+ R Sbjct: 83 HGADFAAEAVRRGAVAVLTDEDGASR--PELRDVPVLVHRDPRAALGALSARVYGEPAQR 140 Query: 132 MXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAM 191 + E T+ RI G + S TTPEAP LQA+ Sbjct: 141 VALWGVTGTSGKTTTSYMIESCLRAEGRVTGLVGTVETRIAGERLDSAFTTPEAPDLQAL 200 Query: 192 LAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVL 251 LA MVERGV VMEVSSHAL LGRV G FAV FTNLS+DHLDFHPDME+YF+AKA L Sbjct: 201 LAVMVERGVGDAVMEVSSHALRLGRVGGAGFAVGAFTNLSQDHLDFHPDMEDYFQAKAEL 260 Query: 252 FDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQEFTA 311 FD RAR VVC +A A+W A+ +R G Q FTA Sbjct: 261 FDG----RARREVVCVDGEWGRRLVKPGTVTVSATAPVGGATWTASGVRVSATGEQTFTA 316 Query: 312 VDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQ 371 P G++ V +RLPG +NVAN L+A+ L GV E G ++++PGR++R+D GQ Sbjct: 317 HGPDGLELAVALRLPGDFNVANALLAIGCLHASGVGAEAIVRGLAEVQVPGRMQRVDVGQ 376 Query: 372 DFLALVDYAHKPGALHSVLTAL-LQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVV 430 DF A+VDY+HKP A+ L A+ + R+ V G GG+RD KR MG AA ++++V Sbjct: 377 DFTAVVDYSHKPAAVVLALDAVRARATGRVITVLGCGGDRDTAKRPLMGAEAARRSEVLV 436 Query: 431 VTDDNPRGEDPAAIRRDIL--XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAG 488 VTDDNPR EDPAAIR +L EIGDR AAI +AV+ A DVV+VAG Sbjct: 437 VTDDNPRSEDPAAIRAAVLAGALEVPEAERGEVVEIGDRGAAIAHAVSLAVAGDVVVVAG 496 Query: 489 KGHETGQRGAAETCPFDDRVELARALQ 515 KGHETGQ A PF D L A+Q Sbjct: 497 KGHETGQEVAGVVHPFSDVDALTGAIQ 523 >tr|A4FLW5|A4FLW5_SACEN Tax_Id=405948 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Saccharopolyspora erythraea] Length = 522 Score = 388 bits (997), Expect = e-106 Identities = 236/504 (46%), Positives = 288/504 (57%), Gaps = 18/504 (3%) Query: 23 ELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALE 82 +L +GA + PGQ + PVTG TLRAQ V GDLFAAL G HGA +A AL+ Sbjct: 5 QLAELIGARILRAPGQGPS--GRPVTGATLRAQHVRPGDLFAALPGTRVHGADFAATALD 62 Query: 83 RGAVAVLTDVAGVAELT------AQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXX 136 GAVAVLTD AGV A V +L+H +PR+ LG AA YG PS ++ Sbjct: 63 AGAVAVLTDQAGVVRADLLDHPEVSAGRVALLVHDDPRAALGPAAAKIYGEPSKQLRILG 122 Query: 137 XXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMV 196 E T+ RI G + S TTPEAP LQA+LA MV Sbjct: 123 VTGTSGKTTTTYLLESALAAAGFTTGLVGTVETRIAGERLDSAFTTPEAPDLQALLAVMV 182 Query: 197 ERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHS 256 E GV V MEVSSHAL+LGRV GT+F V GFTNLS+DHLDFH D+++YF+AKA+LFD Sbjct: 183 EHGVTHVPMEVSSHALALGRVSGTRFTVGGFTNLSQDHLDFHRDLDDYFQAKALLFDG-- 240 Query: 257 LLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAG 316 R+ VVC VS G ASW ATD+ + G QEFTA P G Sbjct: 241 --RSEHEVVC--TDTDWGRKLVKPGTITVSTTGD-ASWTATDVEAFPTGEQEFTAHGPGG 295 Query: 317 VQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLAL 376 + R+ +RLPG +N+AN L+A+ IL V G ++ +PGR+ER+ GQDF A+ Sbjct: 296 LSLRMRLRLPGPFNIANALLAIGILHAAEVPTWAIERGLAEVDVPGRMERVALGQDFTAV 355 Query: 377 VDYAHKPGALHSVL-TALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDN 435 VDY+HKPGA+ +VL A Q + R+ VV G GG+RD KR MGE AA + L++VTDDN Sbjct: 356 VDYSHKPGAVSAVLDAARAQAEGRVIVVLGCGGDRDVAKRPLMGEAAARRSGLLIVTDDN 415 Query: 436 PRGEDPAAIRRDIL--XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHET 493 PR EDPA IR +L E GDRR AI AVA A D+V+VAGKGHET Sbjct: 416 PRSEDPADIRAAMLAGAEAVPAAERGEVIERGDRREAIAEAVARASSGDIVVVAGKGHET 475 Query: 494 GQRGAAETCPFDDRVELARALQVR 517 GQ A PF DR ELA AL+ R Sbjct: 476 GQEVAGVVHPFSDREELAAALRRR 499 >tr|Q0SHR6|Q0SHR6_RHOSR Tax_Id=101510 (murE1)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Rhodococcus sp.] Length = 537 Score = 387 bits (994), Expect = e-105 Identities = 232/520 (44%), Positives = 288/520 (55%), Gaps = 12/520 (2%) Query: 5 VAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFA 64 V V LRP+ + L A GA + G T + VTGV LRAQ ++ GDLFA Sbjct: 14 VKVTDSLRPAQPVRTTVSALAALAGARVEAPTG---TAEHVIVTGVDLRAQGIVEGDLFA 70 Query: 65 ALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAA 124 AL GA HGA +A AL RGA A+LTD AG A ++A S +P+L+H +PR VLG L+A Sbjct: 71 ALPGARAHGAEFAADALARGATAILTDEAGFALVSALGSDMPVLVHDDPRGVLGELSATI 130 Query: 125 YGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPE 184 YG PS +M E TI R+ G +PS LTTPE Sbjct: 131 YGRPSEKMQVIGITGTSGKTTTSYLVEAALTAAGRTTGLVGTIETRMRGRRVPSALTTPE 190 Query: 185 APALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEY 244 AP L A+ A M+E+G++TVVMEVSSHALSLGRV+G +F V FTNLS+DHLDFH D E+Y Sbjct: 191 APQLHALFAVMLEQGIDTVVMEVSSHALSLGRVDGVRFDVGAFTNLSQDHLDFHRDFEDY 250 Query: 245 FEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSAL------GQPASWRATD 298 F AKA LF S + A+ V+C + + A W A Sbjct: 251 FAAKARLFAADSSVHAQHAVICIDDVWGQRMADVARGAHSIVTTVATTPDSEGAVWTAGP 310 Query: 299 IRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDI 358 G+Q F G V +RLPG+YNVAN +A+A+ +GV P A G + Sbjct: 311 ATVSPSGSQTFALTTAEGTTLDVELRLPGQYNVANASLAVALCAALGVDPRDAVEGIAGV 370 Query: 359 RIPGRLERIDCGQDFLALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAP 417 +PGR++RID GQDFLA+VDYAHKP A+ +V+ L Q R+AVV GAGG+RD GKR Sbjct: 371 DVPGRVQRIDRGQDFLAVVDYAHKPAAVEAVIATLREQVRGRVAVVVGAGGDRDAGKRPL 430 Query: 418 MGEIAAELADLVVVTDDNPRGEDPAAIRRDIL--XXXXXXXXXXXXXEIGDRRAAIQYAV 475 MG AA ADL+++TDDNPR EDPA IR + E+ DR AI AV Sbjct: 431 MGAAAARGADLLIITDDNPRSEDPAKIRAAVREGALGVPESERGQVWEVADRAKAIADAV 490 Query: 476 AWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARALQ 515 WA DVVLVAGKGHE GQ PFDDR L A++ Sbjct: 491 GWAQAGDVVLVAGKGHEIGQEIHGVKYPFDDRDVLGDAIE 530 >tr|C7MV98|C7MV98_SACVD Tax_Id=471857 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase;[Saccharomonospora viridis] Length = 524 Score = 383 bits (984), Expect = e-104 Identities = 240/512 (46%), Positives = 285/512 (55%), Gaps = 17/512 (3%) Query: 12 RPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGAST 71 RP V L LVA+ A L P A +V VTG TLRAQ VL GDLFAAL GA Sbjct: 19 RPHLIEPVPLTTLVARADARLVADPAVAESVR---VTGATLRAQHVLPGDLFAALPGARA 75 Query: 72 HGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNR 131 HGA + A+ GAVAVLTD G + + S +P+LIHP+PR VLG +AA YG PS Sbjct: 76 HGADFTADAVAGGAVAVLTDEEGASRPAVRESGLPVLIHPDPRGVLGSVAAWIYGEPSLT 135 Query: 132 MXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAM 191 + E T+ RI + S TTPEAP LQA+ Sbjct: 136 LSVLGITGTSGKTTTSYFVESGLRAAGYHTGLIGTVETRIGSERLASAFTTPEAPDLQAL 195 Query: 192 LAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVL 251 A MVERGV V MEVSSHAL+LGRV GT+F V FTNLS+DHLDFH DME+YF AK++L Sbjct: 196 FADMVERGVTHVAMEVSSHALALGRVNGTRFTVGAFTNLSQDHLDFHRDMEDYFSAKSLL 255 Query: 252 FDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQP---ASWRATDIRSPGVGAQE 308 FD S +VV V+ +P A WRATDI G Q Sbjct: 256 FDGRS---THEIVV-----VDSAWGQALVTPRTVTVSTEPDSDAGWRATDITLTPGGEQS 307 Query: 309 FTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERID 368 FT P G + + + LPG +NVAN ++A AILD VGV + G + +PGR+ER+ Sbjct: 308 FTLHAPDGRKAQAVLPLPGEFNVANAVLAAAILDTVGVDLDAVLEGLATVEVPGRMERVY 367 Query: 369 CGQDFLALVDYAHKPGALHSVLTAL-LQPDHRLAVVFGAGGERDPGKRAPMGEIAAELAD 427 GQ F A+VDYAHKP A+ L AL + + RL V G+GG+RD KR MGE AA +D Sbjct: 368 LGQPFTAVVDYAHKPAAVTQALRALRARTEGRLITVIGSGGDRDTAKRPMMGEAAARGSD 427 Query: 428 LVVVTDDNPRGEDPAAIRRDIL--XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVL 485 LV+VTDDNPR EDPAAIR IL EIGDRR AI AV A DVV Sbjct: 428 LVIVTDDNPRSEDPAAIREAILAGARAVGPAEGCEVLEIGDRREAIAAAVERAEAGDVVF 487 Query: 486 VAGKGHETGQRGAAETCPFDDRVELARALQVR 517 VAGKGHE+GQ A PF DR EL A++ R Sbjct: 488 VAGKGHESGQEVAGVVHPFSDRDELEAAIRER 519 >tr|C0E4M8|C0E4M8_9CORY Tax_Id=566549 SubName: Full=Putative uncharacterized protein;[Corynebacterium matruchotii ATCC 33806] Length = 497 Score = 372 bits (955), Expect = e-101 Identities = 228/497 (45%), Positives = 282/497 (56%), Gaps = 11/497 (2%) Query: 25 VAQ-VGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALER 83 VAQ +GA + G + A VP +T V L + E+ +G LFAA+ G HGAR+A + Sbjct: 8 VAQLIGARMQGGTAEQAQVP---ITEVGLNSAELPAGALFAAVPGTRVHGARFAA---DT 61 Query: 84 GAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXX 143 A A+LTD AG L+A + P+L+ + RSVLG AAA YG PS+++ Sbjct: 62 AAAAILTDEAGWGLLSAAGETRPVLVVDDVRSVLGVAAAAVYGDPSSQLTVIGITGTSGK 121 Query: 144 XXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETV 203 E T G +I+G +P+ LTTPEAP LQA+ M+ GV V Sbjct: 122 TTTSYMLEAGLLAAGYRVGLIGTTGTQINGRPVPTSLTTPEAPTLQALFVQMLAEGVTHV 181 Query: 204 VMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTV 263 VMEVSSHAL LGRV G +F VAGFTNLS+DHLDFH M EYF+AKA+ F P S RA Sbjct: 182 VMEVSSHALMLGRVLGVKFDVAGFTNLSQDHLDFHATMAEYFDAKALFFRPGSPTRAARA 241 Query: 264 VVCXXXXXXXXXXXXXXXXXXVSAL-GQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVG 322 VVC A GQ + + +++ G QEF P+G Sbjct: 242 VVCVDDEWGEKMASVFGSGVRTLATRGQAGDYTVSAVQTVERGGQEFQLAAPSGSVVAAT 301 Query: 323 IRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHK 382 + LPGR+NVAN +ALA+ D VGV G + +PGR+E +DCGQDFLA+VDYAHK Sbjct: 302 VPLPGRFNVANAALALALADTVGVDMTALLPGLAGVGVPGRMEVVDCGQDFLAVVDYAHK 361 Query: 383 PGALHSVL-TALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDP 441 P A+ +VL T Q R+ +V GAGG+RD KR MG AA AD VVVTDDNPR EDP Sbjct: 362 PAAIKAVLATVRGQITGRIGLVVGAGGDRDHSKRPIMGAEAAAGADYVVVTDDNPRNEDP 421 Query: 442 AAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAET 501 AAIR +L EIGDRRAAI+ VAWA P D V++AGKGHE GQ T Sbjct: 422 AAIRAQVL--AGTAAGSAEVVEIGDRRAAIRQVVAWAKPGDAVIIAGKGHEVGQLIDGVT 479 Query: 502 CPFDDRVELARALQVRD 518 FDDR EL AL+ RD Sbjct: 480 HHFDDREELRAALEGRD 496 >tr|C5VD82|C5VD82_9CORY Tax_Id=553207 SubName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium matruchotii ATCC 14266] Length = 497 Score = 370 bits (951), Expect = e-100 Identities = 227/497 (45%), Positives = 281/497 (56%), Gaps = 11/497 (2%) Query: 25 VAQ-VGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALER 83 VAQ +GA + G + A VP +T V L + E+ +G LFAA+ G HGAR+A + Sbjct: 8 VAQLIGARMQGGTAEQAQVP---ITEVGLNSAELPAGALFAAVPGTRVHGARFAA---DT 61 Query: 84 GAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXX 143 A A+LTD AG L+A + P+L+ + RSVLG AAA YG PS+++ Sbjct: 62 AAAAILTDEAGWGLLSAAGETRPVLVVDDVRSVLGVAAAAVYGDPSSQLTVIGITGTSGK 121 Query: 144 XXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETV 203 E T G +I+G +P+ LTTPEAP LQA+ M+ GV V Sbjct: 122 TTTSYMLEAGLLAAGYRVGLIGTTGTQINGRPVPTSLTTPEAPTLQALFVQMLAEGVTHV 181 Query: 204 VMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTV 263 VMEVSSHAL LGRV G +F VAGFTNLS+DHLDFH M EYF+AKA+ F P S RA Sbjct: 182 VMEVSSHALMLGRVLGVKFDVAGFTNLSQDHLDFHATMAEYFDAKALFFRPGSPTRAARA 241 Query: 264 VVCXXXXXXXXXXXXXXXXXXVSAL-GQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVG 322 VVC A GQ + + +++ G QEF P+G Sbjct: 242 VVCVDDEWGEKMASVFGSGVRTLATRGQAGDYTVSAVQTVERGGQEFRLAAPSGAVVAAT 301 Query: 323 IRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHK 382 + LPGR+NVAN +ALA+ D VGV G + +PGR+E +DCGQDFLA+VDYAHK Sbjct: 302 VPLPGRFNVANAALALALADTVGVDMTALLPGLAGVGVPGRMEVVDCGQDFLAVVDYAHK 361 Query: 383 PGALHSVL-TALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDP 441 P A+ +VL T Q R+ +V GAGG+RD KR MG AA AD VVVTDDNPR EDP Sbjct: 362 PAAIKAVLATVRGQITGRIGLVVGAGGDRDHSKRPIMGAEAAAGADYVVVTDDNPRNEDP 421 Query: 442 AAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAET 501 AAIR +L EIGDRRAAI+ VAWA P D V++AGKGHE GQ Sbjct: 422 AAIRAQVL--AGTAAGSAEVVEIGDRRAAIRQVVAWAKPGDAVIIAGKGHEVGQLIDGVM 479 Query: 502 CPFDDRVELARALQVRD 518 FDDR EL AL+ RD Sbjct: 480 HHFDDREELRAALEGRD 496 >sp|Q8NNN0|MURE_CORGL Tax_Id=1718 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Corynebacterium glutamicum] Length = 517 Score = 367 bits (941), Expect = 3e-99 Identities = 218/491 (44%), Positives = 276/491 (56%), Gaps = 6/491 (1%) Query: 39 AATVPDIPVTGVTLRAQEVLSGD-LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAE 97 A V + + + L + + + D +FAA+ G THGA++AG AVA+LTD AG+ Sbjct: 21 AHAVGEQAIAAIGLDSSSLPTSDAIFAAVPGTRTHGAQFAGTDNAAKAVAILTDAAGLEV 80 Query: 98 LTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXX 157 L + P+++ + R+VLG +++ YG PS E Sbjct: 81 LNEAGETRPVIVVDDVRAVLGAASSSIYGDPSKDFTLIGVTGTSGKTTTSYLLEKGLMEA 140 Query: 158 XXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRV 217 T G RIDG ++P+ LTTPEAP LQA+ A M + GV VVMEVSSHALSLGRV Sbjct: 141 GHKVGLIGTTGTRIDGEEVPTKLTTPEAPTLQALFARMRDHGVTHVVMEVSSHALSLGRV 200 Query: 218 EGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXX 277 G+ F VA FTNLS+DHLDFHP M++YF+AKA+ F S L A VVC Sbjct: 201 AGSHFDVAAFTNLSQDHLDFHPTMDDYFDAKALFFRADSPLVADKQVVCVDDSWGQRMAS 260 Query: 278 XXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVA 337 VS LGQ A + ATDI GAQ F P+ ++V + LPG +NVAN +A Sbjct: 261 VAADVQTVSTLGQEADFSATDINVSDSGAQSFKINAPSNQSYQVELALPGAFNVANATLA 320 Query: 338 LAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTAL-LQP 396 A VGV E + G + +PGR+ERID GQDFLA+VDYAHKP A+ +VL L Q Sbjct: 321 FAAAARVGVDGEAFARGMSKVAVPGRMERIDEGQDFLAVVDYAHKPAAVAAVLDTLRTQI 380 Query: 397 DHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDIL----XXX 452 D RL VV GAGG+RD KR PMG+++A+ ADLV+VTDDNPR E PA IR + Sbjct: 381 DGRLGVVIGAGGDRDSTKRGPMGQLSAQRADLVIVTDDNPRSEVPATIRAAVTAGAQQGA 440 Query: 453 XXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELAR 512 EIGDR AI+ V WA P D ++VAGKGHE GQ A T FDDR E+ Sbjct: 441 SESERPVEVLEIGDRAEAIRVLVEWAQPGDGIVVAGKGHEVGQLVAGVTHHFDDREEVRA 500 Query: 513 ALQVRDARLLP 523 AL + LP Sbjct: 501 ALTEKLNNKLP 511 >tr|A4QFM8|A4QFM8_CORGB Tax_Id=340322 SubName: Full=Putative uncharacterized protein;[Corynebacterium glutamicum] Length = 521 Score = 367 bits (941), Expect = 3e-99 Identities = 218/491 (44%), Positives = 276/491 (56%), Gaps = 6/491 (1%) Query: 39 AATVPDIPVTGVTLRAQEVLSGD-LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAE 97 A V + + + L + + + D +FAA+ G THGA++AG AVA+LTD AG+ Sbjct: 25 AHAVGEQAIAAIGLDSSSLPTSDAIFAAVPGTRTHGAQFAGTDNAAKAVAILTDAAGLEV 84 Query: 98 LTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXX 157 L + P+++ + R+VLG +++ YG PS E Sbjct: 85 LNEAGETRPVIVVDDVRAVLGAASSSIYGDPSKDFTLIGVTGTSGKTTTSYLLEKGLMEA 144 Query: 158 XXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRV 217 T G RIDG ++P+ LTTPEAP LQA+ A M + GV VVMEVSSHALSLGRV Sbjct: 145 GHKVGLIGTTGTRIDGEEVPTKLTTPEAPTLQALFARMRDHGVTHVVMEVSSHALSLGRV 204 Query: 218 EGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXX 277 G+ F VA FTNLS+DHLDFHP M++YF+AKA+ F S L A VVC Sbjct: 205 AGSHFDVAAFTNLSQDHLDFHPTMDDYFDAKALFFRADSPLVADKQVVCVDDSWGQRMAS 264 Query: 278 XXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVA 337 VS LGQ A + ATDI GAQ F P+ ++V + LPG +NVAN +A Sbjct: 265 VAADVQTVSTLGQEADFSATDINVSDSGAQSFKINAPSNQSYQVELALPGAFNVANATLA 324 Query: 338 LAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTAL-LQP 396 A VGV E + G + +PGR+ERID GQDFLA+VDYAHKP A+ +VL L Q Sbjct: 325 FAAAARVGVDGEAFARGMSKVAVPGRMERIDEGQDFLAVVDYAHKPAAVAAVLDTLRTQI 384 Query: 397 DHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDIL----XXX 452 D RL VV GAGG+RD KR PMG+++A+ ADLV+VTDDNPR E PA IR + Sbjct: 385 DGRLGVVIGAGGDRDSTKRGPMGQLSAQRADLVIVTDDNPRSEVPATIRAAVTAGAQQGA 444 Query: 453 XXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELAR 512 EIGDR AI+ V WA P D ++VAGKGHE GQ A T FDDR E+ Sbjct: 445 SESERPVEVLEIGDRAEAIRVLVEWAQPGDGIVVAGKGHEVGQLVAGVTHHFDDREEVRA 504 Query: 513 ALQVRDARLLP 523 AL + LP Sbjct: 505 ALTEKLNNKLP 515 >tr|C8XGZ1|C8XGZ1_NAKMY Tax_Id=479431 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Nakamurella multipartita] Length = 533 Score = 366 bits (940), Expect = 4e-99 Identities = 231/487 (47%), Positives = 273/487 (56%), Gaps = 14/487 (2%) Query: 47 VTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTA--QASS 104 +TG+TLRAQ+V DLFAAL G+ HGA YAG ALERGA AVLTD AG AEL A S Sbjct: 22 LTGITLRAQDVRPHDLFAALPGSRAHGAGYAGQALERGAAAVLTDRAG-AELLAGTDLGS 80 Query: 105 VPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXX 164 V +L+ PR LG +A YG PS R+ E Sbjct: 81 VALLVVERPREHLGAIARQLYGDPSRRLAVVGVTGTSGKTTTCYLLEAALAADGSRSAVI 140 Query: 165 XTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAV 224 T+ RIDG PS LTTPEAP LQA+LA MVERGV V MEVSSHALSLGRV GT+FAV Sbjct: 141 GTVQTRIDGQITPSALTTPEAPDLQALLAVMVERGVGAVAMEVSSHALSLGRVSGTRFAV 200 Query: 225 AGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXX 284 FTNLS+DHLDFH DME+YF AKA+LFD RA V+ Sbjct: 201 GAFTNLSQDHLDFHHDMEDYFRAKAMLFDG----RAGAHVIDVDTEYGARLAAEHPEALT 256 Query: 285 VSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVV 344 VS A W + G Q P Q + + +PG +NV N VALA +D + Sbjct: 257 VSDRPGAADWSVEMVTLAANGVQHVVLSGPGKRQVTLDLAIPGAFNVGNAAVALACVDAL 316 Query: 345 GVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQP-DHRLAVV 403 G +QA+ + +PGR+ER+D GQDFLA+VDYAHKPGA+ +VL A+ Q L VV Sbjct: 317 GRDVQQAADALATVVVPGRMERVDAGQDFLAVVDYAHKPGAVAAVLDAIGQGLAGPLIVV 376 Query: 404 FGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDIL--XXXXXXXXXXXX 461 GAGG+RD GKR MG +A AD+++VTDDNPR E PA IR +L Sbjct: 377 LGAGGDRDTGKRPMMGAESAARADVLIVTDDNPRSERPADIRAQVLAGAAPVADRRPCQV 436 Query: 462 XEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARL 521 EIGDRRAAI+ AV AG V++AGKGHE GQ PF DR EL AL L Sbjct: 437 LEIGDRRAAIRRAVQLAGTGGAVVIAGKGHEQGQEIDGVVHPFSDRDELRAAL----VAL 492 Query: 522 LPAPGRA 528 + GRA Sbjct: 493 VEPAGRA 499 >tr|C0XS01|C0XS01_9CORY Tax_Id=525263 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium lipophiloflavum DSM 44291] Length = 545 Score = 365 bits (936), Expect = 1e-98 Identities = 226/502 (45%), Positives = 273/502 (54%), Gaps = 12/502 (2%) Query: 17 AGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARY 76 A V L EL GA +A + ++ V L A+EV G LFAAL G HGA++ Sbjct: 15 APVPLHELARIAGADVASSADNGWA--GVAISSVGLNAREVAPGGLFAALPGTRVHGAQF 72 Query: 77 AGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXX 136 A E A A+LTD G+ + A P+L+ + R+VLG ++A YGHPS RM Sbjct: 73 AA---ESPARAILTDREGLDIVEAAGDRRPVLVVDDVRAVLGEVSAHVYGHPSRRMTLIG 129 Query: 137 XXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMV 196 E T G RI G D+P+ LTTPEAP LQA+ A M Sbjct: 130 VTGTSGKTTTTYLLERGLIAAGAQVGLIGTTGTRIRGRDVPTSLTTPEAPTLQALFARMA 189 Query: 197 ERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHS 256 GV VVMEVSSHALSLGRV+GT F AGFTNLS+DHLDFHP M++YF+AKA FDP S Sbjct: 190 AEGVTHVVMEVSSHALSLGRVDGTSFDAAGFTNLSQDHLDFHPTMDDYFQAKAAFFDPSS 249 Query: 257 LLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQ---PASWRATDIRSPGVGAQEFTAVD 313 + A VVC V GQ S R T +R G E +D Sbjct: 250 PVAASASVVCVDDEWGERMAELASHPLRVGTHGQEGLDCSARLTAVRDNGAQDIEL-RID 308 Query: 314 PAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDF 373 G H + LPG +NVAN +A A+ VVG Q G + +PGR+ERID GQDF Sbjct: 309 --GQTHEFTLPLPGAFNVANAALATALARVVGADMPQFVRGLENAAVPGRMERIDAGQDF 366 Query: 374 LALVDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVT 432 +A+VDYAHKP A+ +VL L Q D R+ + GAGG+RD KRA MG+ AA ADLV+VT Sbjct: 367 VAVVDYAHKPAAIAAVLETLREQVDGRIGIAVGAGGDRDTTKRAVMGQQAATRADLVIVT 426 Query: 433 DDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHE 492 DDNPR EDPAAIR +L E G R AI VAWA P D ++V GKGHE Sbjct: 427 DDNPRTEDPAAIRAAVLRGAREAGSGAEIRECGPRAEAIDQLVAWALPGDAIVVVGKGHE 486 Query: 493 TGQRGAAETCPFDDRVELARAL 514 GQ T FDDR E+ RAL Sbjct: 487 VGQIVGDTTHHFDDREEMRRAL 508 >tr|A8KZA6|A8KZA6_FRASN Tax_Id=298653 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Frankia sp.] Length = 513 Score = 361 bits (927), Expect = 1e-97 Identities = 224/511 (43%), Positives = 284/511 (55%), Gaps = 11/511 (2%) Query: 13 PSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTH 72 PS + LP+++ + +A GP A + + +TGVT ++ VL GDL+AAL GA H Sbjct: 11 PSPRSLTALPDVLRSI--TVAPGPSGGAALAGVVLTGVTHDSRAVLPGDLYAALPGAHVH 68 Query: 73 GARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRM 132 GA +A A+ GAVAVLTD G A L+ + + VP+L+ +PR L AA YG PS+ + Sbjct: 69 GADFAAGAVAAGAVAVLTDPVGAAALSGRLA-VPVLVTDDPRRDLAPAAAWIYGDPSSAL 127 Query: 133 XXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAML 192 + T+ R+ G +PS TTPE+ LQA+L Sbjct: 128 TLLGVTGTNGKTTTAFLLDAGLRAAGYTTGLLGTVQTRVAGTVVPSVRTTPESGDLQALL 187 Query: 193 AAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLF 252 A MVERGV MEVSSHAL+ RV+ +FA A FTNLS+DHLDFHP ME+YF AKA LF Sbjct: 188 ATMVERGVGAASMEVSSHALAQHRVDALRFAGAAFTNLSQDHLDFHPTMEDYFAAKAALF 247 Query: 253 DPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAV 312 +P R+ VVC S G+PA W D+ + G G F A+ Sbjct: 248 EP---ARSAAAVVCVDDDWGRRLAALRPDARTYSVTGRPADWWPEDVVA-GPGGSVFRAL 303 Query: 313 DPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDI-RIPGRLERIDCGQ 371 P G + + + LPGR+NVAN L ALA+L VGV E A+ G + +PGR+ERID GQ Sbjct: 304 GPDGAKADLSLALPGRFNVANALGALALLAAVGVPLEAAAEGISSLPGVPGRMERIDAGQ 363 Query: 372 DFLALVDYAHKPGALHSVLTALLQP--DHRLAVVFGAGGERDPGKRAPMGEIAAELADLV 429 FLALVDYAH PGA+ ++L A ++P R+ VV G GG+RD KR MG AA LADL Sbjct: 364 PFLALVDYAHTPGAVETLL-ATVRPIVTGRVVVVLGCGGDRDRAKRPLMGAAAARLADLA 422 Query: 430 VVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGK 489 V T DNPR EDPA I +L DR +AI AV AGP D V+VAGK Sbjct: 423 VFTSDNPRSEDPARILEQMLAGARGAPGAGEIVVEPDRASAIALAVGAAGPTDAVIVAGK 482 Query: 490 GHETGQRGAAETCPFDDRVELARALQVRDAR 520 GHE+GQ A PFDDR L AL +R Sbjct: 483 GHESGQDVAGVVTPFDDREVLRSALLAAASR 513 >tr|Q6NGC3|Q6NGC3_CORDI Tax_Id=1717 (murE)SubName: Full=UDP-N-acetylmuramoyl-L-alanyl-D- glutamate;[Corynebacterium diphtheriae] Length = 513 Score = 356 bits (914), Expect = 4e-96 Identities = 214/474 (45%), Positives = 264/474 (55%), Gaps = 7/474 (1%) Query: 47 VTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVP 106 ++ + L + ++ + +FAAL G THGA YA A+AVL+D G L P Sbjct: 33 ISAIGLDSSQLPADAIFAALPGTKTHGAHYASQGKAAAALAVLSDHEGTQILVDSGEKRP 92 Query: 107 ILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXT 166 I+ + R VLG L+A YGHPS+ M E T Sbjct: 93 IIEVDDVRRVLGILSAEIYGHPSHEMTIIGVTGTSGKTTTSYILERGLMAAGLHVGLIGT 152 Query: 167 IGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAG 226 G RI+G +P+ LTTPEAP LQ + + M GV VVMEVSSHAL+LGRV GT+F+ AG Sbjct: 153 TGTRINGRKVPTKLTTPEAPTLQQLFSQMKAEGVSHVVMEVSSHALALGRVTGTRFSAAG 212 Query: 227 FTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXV- 285 FTNLS+DHLDFHP M+EYFEAKA+ FDP S + A VVC Sbjct: 213 FTNLSQDHLDFHPTMQEYFEAKALFFDPASPIHAEKSVVCVNDLWGKNMAERAGADAITV 272 Query: 286 ----SALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAIL 341 A A + ++I VGAQ F V V + LPG +N+AN +VALA+ Sbjct: 273 CTEQEAAAHQADYWVSNIDVNPVGAQSF-IVHHGAQSTDVHLPLPGGFNIANTVVALALA 331 Query: 342 DVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVL-TALLQPDHRL 400 + VGV + G D+ +PGR+ERID GQ+FLA+VDYAHKP A+ V+ T Q R+ Sbjct: 332 ESVGVDTDAFIRGIADVAVPGRMERIDRGQEFLAVVDYAHKPAAVAVVIDTVRDQVPGRI 391 Query: 401 AVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXX 460 AVV GAGG+RD GKR MG AA ADLV+VTDDNPR EDPA IR +L Sbjct: 392 AVVVGAGGDRDSGKRPIMGAEAARRADLVIVTDDNPRSEDPAKIREAVLEGAHGVAGSAD 451 Query: 461 XXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARAL 514 EIGDRR AI+ AV WA P D V+VAGKGHE GQ FDDR E+A AL Sbjct: 452 IREIGDRREAIRIAVQWAQPGDAVIVAGKGHEVGQLINGVDHHFDDREEVAAAL 505 >tr|C4LI45|C4LI45_CORK4 Tax_Id=645127 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium kroppenstedtii] Length = 526 Score = 354 bits (909), Expect = 1e-95 Identities = 217/504 (43%), Positives = 278/504 (55%), Gaps = 38/504 (7%) Query: 43 PDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQA 102 PD+ VT + L AQ + G LFA + G HGA++A + A AVLTD GV ++T + Sbjct: 21 PDLVVTDIGLNAQALPEGGLFAGVPGLHVHGAQFADSS---SAAAVLTDHDGVEKVTRE- 76 Query: 103 SSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXX 162 +PI++ + R+VLG +++A Y HPS + E Sbjct: 77 -DLPIIVVDDVRAVLGEVSSAVYDHPSRDLTVIGITGTAGKTTTSYMVEAALLHHGISTG 135 Query: 163 XXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQF 222 T G RI+G +PS LTTPEAP LQA+ A M +RGV VVMEVSSHA++LGRV GT F Sbjct: 136 LIGTTGTRINGEKVPSTLTTPEAPNLQALFAMMKKRGVTHVVMEVSSHAIALGRVLGTHF 195 Query: 223 AVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXX 282 +VAGFTNLS+DHLDFHP ME+YF+ KA LF S L A T VVC Sbjct: 196 SVAGFTNLSQDHLDFHPTMEDYFQTKARLFKEDSPLHAETSVVCIDDAWGQRLATMLPHP 255 Query: 283 XXVS--------ALGQPASWRA-TDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVAN 333 VS A QP W + + GV E + + I +PGR+NVAN Sbjct: 256 FTVSTEAASEHDASLQPDVWAGPSSVMDNGVQTAELYGF--GANEMTLHIPMPGRFNVAN 313 Query: 334 CLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTAL 393 ++A+ +L G+ E A G + +PGRLERIDCGQDF+A+VDYAHKPGA+ +VL L Sbjct: 314 AMLAMGLLVKTGMKAEDAIEGLSTVTVPGRLERIDCGQDFMAVVDYAHKPGAIAAVLDTL 373 Query: 394 -LQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDIL--- 449 R+A+V GAGG+RD KR MG AA +DLV+VTDDNPR EDPA+IR+ ++ Sbjct: 374 RAHVRGRIAIVVGAGGDRDHSKRPIMGREAALRSDLVIVTDDNPRSEDPASIRQQVVAGA 433 Query: 450 ------------------XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGH 491 EIGDRR AI+ A+ W P D V+VAGKGH Sbjct: 434 KEVADHVDVDRADEPRNKVKTEGSEHRPTIREIGDRREAIRAAIQWTQPGDAVIVAGKGH 493 Query: 492 ETGQRGAAETCPFDDRVELARALQ 515 ETGQ T PFDDRVE R+++ Sbjct: 494 ETGQLIGDTTHPFDDRVETRRSIE 517 >sp|Q8FNT5|MURE_COREF Tax_Id=152794 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Corynebacterium efficiens] Length = 526 Score = 352 bits (903), Expect = 7e-95 Identities = 217/513 (42%), Positives = 273/513 (53%), Gaps = 9/513 (1%) Query: 8 PVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALA 67 P + + L EL +G L + P Q + +I + TL + +FAA+ Sbjct: 9 PTPVHTEEAMAITLGELARTIGGELFNAPDQDLEIHNIGLDSSTLAKK----APIFAAVP 64 Query: 68 GASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGH 127 G+ HGA +A GA+AVLTD G L + + P LI + R VLG +++ YG Sbjct: 65 GSRKHGAEFADTDRAAGALAVLTDRDGATILDRKGDTRPRLIVDDVREVLGVASSSVYGD 124 Query: 128 PSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPA 187 PS + E T G RIDG +P+ LTTPEAP Sbjct: 125 PSRDLVLIGVTGTSGKTTTSYLLERGLMEAGYKVGLIGTTGTRIDGEPVPTKLTTPEAPT 184 Query: 188 LQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEA 247 LQ + M + GV VVMEVSSHALSLGRV G+ F VA FTNLS+DHLDFH MEEYF+A Sbjct: 185 LQKLFYRMRQHGVTHVVMEVSSHALSLGRVSGSHFNVAAFTNLSQDHLDFHDTMEEYFDA 244 Query: 248 KAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQ 307 KA+ F S L A VVC V+ G+ A + A + G Q Sbjct: 245 KALFFRAGSPLAADHQVVCIDDEWGTRMAEVAGNAQTVATTGKRADFTAGLVTVKETGEQ 304 Query: 308 EFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERI 367 FT P + V + LPG +NVAN +ALA GV P + G + +PGR+ERI Sbjct: 305 SFTVTVPDHGEVPVTLALPGAFNVANATLALAAAVRAGVDPVAFARGMAQVAVPGRMERI 364 Query: 368 DCGQDFLALVDYAHKPGALHSVLTAL-LQPDHRLAVVFGAGGERDPGKRAPMGEIAAELA 426 D GQDFLA+VDYAHKP A+ +VL L Q D RL VV GAGG+RD KRAPMGE++A A Sbjct: 365 DEGQDFLAVVDYAHKPAAVAAVLDTLRTQIDGRLGVVIGAGGDRDATKRAPMGELSARRA 424 Query: 427 DLVVVTDDNPRGEDPAAIRRDIL----XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDD 482 DLV+VTDDNPR E PA IR ++ EIGDR AI+ + WAGP D Sbjct: 425 DLVIVTDDNPRSEVPATIRAAVMEGARRGAAEADHEVEVREIGDRAEAIRALIEWAGPGD 484 Query: 483 VVLVAGKGHETGQRGAAETCPFDDRVELARALQ 515 ++VAGKGHE GQ A T FDDR ++ AL+ Sbjct: 485 GIVVAGKGHEVGQLIAGVTHHFDDREQVREALR 517 >tr|C8NQ17|C8NQ17_COREF Tax_Id=196164 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium efficiens YS-314] Length = 509 Score = 351 bits (900), Expect = 2e-94 Identities = 216/502 (43%), Positives = 271/502 (53%), Gaps = 9/502 (1%) Query: 19 VRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAG 78 + L EL +G L + P Q + +I + TL + +FAA+ G+ HGA +A Sbjct: 3 ITLGELARTIGGELFNAPDQDLEIHNIGLDSSTLAKK----APIFAAVPGSRKHGAEFAD 58 Query: 79 VALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXX 138 GA+AVLTD G L + + P LI + R VLG +++ YG PS + Sbjct: 59 TDRAAGALAVLTDRDGATILDRKGDTRPRLIVDDVREVLGVASSSVYGDPSRDLVLIGVT 118 Query: 139 XXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVER 198 E T G RIDG +P+ LTTPEAP LQ + M + Sbjct: 119 GTSGKTTTSYLLERGLMEAGYKVGLIGTTGTRIDGEPVPTKLTTPEAPTLQKLFYRMRQH 178 Query: 199 GVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLL 258 GV VVMEVSSHALSLGRV G+ F VA FTNLS+DHLDFH MEEYF+AKA+ F S L Sbjct: 179 GVTHVVMEVSSHALSLGRVSGSHFNVAAFTNLSQDHLDFHDTMEEYFDAKALFFRAGSPL 238 Query: 259 RARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQ 318 A VVC V+ G+ A + A + G Q FT P + Sbjct: 239 AADHQVVCIDDEWGTRMAEVAGNAQTVATTGKRADFTAGLVTVKETGEQSFTVTVPDHGE 298 Query: 319 HRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVD 378 V + LPG +NVAN +ALA GV P + G + +PGR+ERID GQDFLA+VD Sbjct: 299 VPVTLALPGAFNVANATLALAAAVRAGVDPVAFARGMAQVAVPGRMERIDEGQDFLAVVD 358 Query: 379 YAHKPGALHSVLTAL-LQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPR 437 YAHKP A+ +VL L Q D RL VV GAGG+RD KRAPMGE++A ADLV+VTDDNPR Sbjct: 359 YAHKPAAVAAVLDTLRTQIDGRLGVVIGAGGDRDATKRAPMGELSARRADLVIVTDDNPR 418 Query: 438 GEDPAAIRRDIL----XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHET 493 E PA IR ++ EIGDR AI+ + WAGP D ++VAGKGHE Sbjct: 419 SEVPATIRAAVMEGARRGAAEADHEVEVREIGDRAEAIRALIEWAGPGDGIVVAGKGHEV 478 Query: 494 GQRGAAETCPFDDRVELARALQ 515 GQ A T FDDR ++ AL+ Sbjct: 479 GQLIAGVTHHFDDREQVREALR 500 >tr|A1SL85|A1SL85_NOCSJ Tax_Id=196162 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Nocardioides sp.] Length = 504 Score = 348 bits (893), Expect = 1e-93 Identities = 221/503 (43%), Positives = 271/503 (53%), Gaps = 24/503 (4%) Query: 12 RPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGAST 71 RP+ L + A GA L P + V+G++L +Q + GDL+AAL G+ Sbjct: 7 RPAQPPRTPLATVAAWAGAELRGNPA------GLEVSGISLSSQRIRPGDLYAALPGSRA 60 Query: 72 HGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNR 131 HG +A AL GAVAV TD AG A A P L+ PR+VLG L+A YG P+ Sbjct: 61 HGIEFAQDALAAGAVAVFTDEAGADRGPAGA---PHLVVDRPRAVLGRLSARIYGEPAAS 117 Query: 132 MXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAM 191 M E T+G RI G ++ S LTTPEAP L A+ Sbjct: 118 MRMVGVTGTQGKTTTTRLLEAGLQQAGVPAAVVGTVGTRIAGEEVRSSLTTPEAPDLHAL 177 Query: 192 LAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVL 251 A M ER V MEVSSHAL +GRV+G F VA F NL RDHLDFH D+E+Y+ AKA L Sbjct: 178 FAVMRERDVRACAMEVSSHALVMGRVDGVVFDVAVFLNLGRDHLDFHRDLEDYYAAKASL 237 Query: 252 FDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALG-----QPASWRATDIRSPGVGA 306 F P RAR +V ++G Q A WRA D+R G+ Sbjct: 238 FTPE---RARFALVNVDDAHGRRLAEEATVPVRTFSMGRGDDAQRADWRAVDVRLRATGS 294 Query: 307 QEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDI-RIPGRLE 365 EF V P G + G LPG +NVAN L A+A G+ P + G +PGRLE Sbjct: 295 -EFVVVAPDGRRIPAGCALPGDFNVANTLAAVAAAAEAGLDPAVVAAGIAAAGGVPGRLE 353 Query: 366 RIDCGQDFLALVDYAHKPGALHSVLTALLQ-PDHRLAVVFGAGGERDPGKRAPMGEIAAE 424 R+D GQDFL +VDYAHKP A+ + + L + R+ VV GAGG+RDPGKR M IAA Sbjct: 354 RVDAGQDFLVVVDYAHKPDAVEAAIRTLRPLTEGRVIVVLGAGGDRDPGKRPIMAGIAAR 413 Query: 425 LADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVV 484 LADL+VVTDDNPR EDPAAIR +L E+G RRAAI+ A+ AGP D+V Sbjct: 414 LADLLVVTDDNPRTEDPAAIRAAML----AGVVTGQAIEVGGRRAAIREALRRAGPGDIV 469 Query: 485 LVAGKGHETGQRGAAETCPFDDR 507 L+AGKGHETGQ PFDDR Sbjct: 470 LIAGKGHETGQEVDGVVHPFDDR 492 >tr|C8NTK7|C8NTK7_9CORY Tax_Id=585529 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium genitalium ATCC 33030] Length = 498 Score = 340 bits (871), Expect = 4e-91 Identities = 217/507 (42%), Positives = 268/507 (52%), Gaps = 17/507 (3%) Query: 17 AGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARY 76 A V L L GA + + P + + V+ ++L + V SG +FAAL G HGA + Sbjct: 2 AKVSLENLAEIAGARVENAPESS-----LSVSAISLDSNAVKSGAMFAALPGTRVHGATF 56 Query: 77 AGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXX 136 A + A AVLTD AG L P+L+ R +LG +AA YGHP+ + Sbjct: 57 AHAS---DASAVLTDDAGWDILRETGFERPVLVVERVRDILGDVAAEIYGHPTEHLTVIG 113 Query: 137 XXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMV 196 E T G RI G D+P+ LTTPEAP LQ + A MV Sbjct: 114 VTGTSGKTTTTYLLESGLTAAGCAVGLIGTTGTRIKGEDVPTSLTTPEAPKLQELFADMV 173 Query: 197 ERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHS 256 RGV VVMEVSSHAL LGRV+GT+FA AGFTNLS+DHLDFHP ME+YFEAKA+LFD Sbjct: 174 SRGVTHVVMEVSSHALVLGRVDGTKFAAAGFTNLSQDHLDFHPTMEDYFEAKAILFD--- 230 Query: 257 LLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAG 316 RA VVC V A A GAQ+ T V G Sbjct: 231 --RAEKAVVCIDDEWGQKMTQRAHSPVTVGVHNTSADCTARLDSVTESGAQDIT-VRIGG 287 Query: 317 VQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLAL 376 I LPG +N+AN +A A+ D VG+ P+ G R+PGR+ER+ GQ F+A+ Sbjct: 288 QDISTRIPLPGAFNIANTALATALADSVGIDPKVFLQGLDAARVPGRMERVSVGQPFVAV 347 Query: 377 VDYAHKPGALHSVLTALL-QPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDN 435 VDYAHKP A+ + L +L Q D R+ VV GAGG+RD KR MG AA ADLV++TDDN Sbjct: 348 VDYAHKPAAVAAALDSLREQVDGRIGVVVGAGGDRDHSKRPLMGAEAATRADLVIITDDN 407 Query: 436 PRGEDPAAIRRDIL--XXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHET 493 PR EDPAAIR + E+ R AI VAWA P D ++V GKGHE Sbjct: 408 PRTEDPAAIRAAVKQGAESVIDGAATDIREVASRAQAIADLVAWAEPGDAIIVVGKGHEV 467 Query: 494 GQRGAAETCPFDDRVELARALQVRDAR 520 GQ T FDDR E+A AL R+ + Sbjct: 468 GQIIGETTHHFDDREEVAFALARREGK 494 >tr|A8LX85|A8LX85_SALAI Tax_Id=391037 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Salinispora arenicola] Length = 515 Score = 338 bits (868), Expect = 8e-91 Identities = 224/511 (43%), Positives = 273/511 (53%), Gaps = 14/511 (2%) Query: 12 RPSATAGVRLPELVAQVGAVLADGPGQAATVPDIP-VTGVTLRAQEVLSGDLFAALAGAS 70 RP G+RL +L ++ A G P P VTGVT +QEV GDL+AAL GA Sbjct: 6 RPRRVTGIRLGDLADRLAAEPDAGTVNLRPGPSEPTVTGVTHASQEVRPGDLYAALPGAR 65 Query: 71 THGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSN 130 HGA + A GAVAVLTD AG A TAQA +P+L+ P+PR+VLG LA+A YG P+ Sbjct: 66 RHGAEFVPAAARAGAVAVLTDPAG-ASATAQAG-LPMLVVPDPRAVLGDLASAVYGDPTA 123 Query: 131 RMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQA 190 + E T+ R+ + S TTPEA L A Sbjct: 124 GLAVIGVTGTAGKTSTAYLVESGLRAAGHVTGLIGTVETRLGDLAMDSVRTTPEATDLHA 183 Query: 191 MLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAV 250 MLAA ERGV VVMEVSSHAL++GRV G +F V G+TN DHLDFH D +YF AKA Sbjct: 184 MLAAARERGVTAVVMEVSSHALAMGRVGGVRFTVGGYTNFGSDHLDFHVDSADYFAAKAK 243 Query: 251 LFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALG-QPASWRATDIRSPGVGAQEF 309 LFD R V SA G + A+W A + G AQ F Sbjct: 244 LFD------GRCEVEVLNHDDPALRPLYRQATVTYSAAGDRSATWWADAVGGEGY-AQRF 296 Query: 310 TAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIR-IPGRLERID 368 T P G+ G+ LPGR+NVAN L+A+A+L GV + A+ G +PGRLE + Sbjct: 297 TLHGPDGLALPAGVALPGRHNVANALLAIAVLVAAGVDAKTAAAGVAACGGVPGRLELVR 356 Query: 369 CGQDFLALVDYAHKPGALHSVLTALLQ--PDHRLAVVFGAGGERDPGKRAPMGEIAAELA 426 +VDYAHK A+ + L AL + RL + GAGG+RD GKR MG AAE A Sbjct: 357 APGPVRGVVDYAHKTDAIVAALAALREFGAGRRLICLLGAGGDRDRGKRPLMGIAAAEGA 416 Query: 427 DLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLV 486 D+VVVTDDNPR E+PA IR ++L E+ RRAAI AV A P DVV + Sbjct: 417 DVVVVTDDNPRTEEPAEIRAEVLAGAYRAGTDARVLEVPGRRAAIAEAVRLAEPGDVVAL 476 Query: 487 AGKGHETGQRGAAETCPFDDRVELARALQVR 517 GKGHE GQ E PFDDR ELA AL+ R Sbjct: 477 LGKGHEQGQEVDGEVQPFDDRTELAAALRAR 507 >tr|A4X9S0|A4X9S0_SALTO Tax_Id=369723 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Salinispora tropica] Length = 514 Score = 338 bits (867), Expect = 1e-90 Identities = 221/510 (43%), Positives = 270/510 (52%), Gaps = 13/510 (2%) Query: 12 RPSATAGVRLPELVAQVGAVLADGPGQAATVPDIP-VTGVTLRAQEVLSGDLFAALAGAS 70 RP + G+RL L A++ A P P VTGVT +QEV GDL+AAL GA Sbjct: 6 RPRSVTGIRLGNLAARLAAESGADAVDLRPGPTEPTVTGVTHASQEVRPGDLYAALPGAR 65 Query: 71 THGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSN 130 HGA + A GAVAVLTD G A TA+ +P+L+ P+PR+VLG LA+ YG P+ Sbjct: 66 RHGAEFVSAAARAGAVAVLTDPDGAAA-TAEVD-LPMLVVPDPRAVLGDLASVVYGDPTA 123 Query: 131 RMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQA 190 + E T+ R+ + S TTPEA L A Sbjct: 124 GLTVIGVTGTAGKTSTAYLVESGLRAAGHTTGLIGTVETRLGDLVVDSVRTTPEATDLHA 183 Query: 191 MLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAV 250 MLAA ERGV VVMEVSSHAL++GRV G +F V G+TN DHLDFH D +YF AKA Sbjct: 184 MLAAARERGVTAVVMEVSSHALAMGRVGGVRFTVGGYTNFGSDHLDFHADSVDYFAAKAK 243 Query: 251 LFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVSALGQ-PASWRATDIRSPGVGAQEF 309 LFD R V SA G A+W A + G AQ F Sbjct: 244 LFD------GRCEVEVLNHDDPALLPLHRPATVTYSAAGDGAATWWADEAGGEGY-AQRF 296 Query: 310 TAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIR-IPGRLERID 368 T P G+ G+ LPGR+NVAN L+A+A+L GV+P A G D +PGRLE + Sbjct: 297 TLHGPDGLTLPAGVALPGRHNVANALLAVAVLVAAGVAPRTAVAGVADCGGVPGRLELVP 356 Query: 369 CGQDFLALVDYAHKPGALHSVLTALLQ-PDHRLAVVFGAGGERDPGKRAPMGEIAAELAD 427 +VDYAHK A+ + L AL + RL + GAGG+RD GKR MG AAE AD Sbjct: 357 SPGPVRGVVDYAHKTDAIVAALAALREFSTGRLICLLGAGGDRDRGKRPLMGVAAAEGAD 416 Query: 428 LVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVA 487 +V+VTDDNPR EDPA IR ++L E+ RRAAI AV A P DVV + Sbjct: 417 VVLVTDDNPRTEDPADIRAEVLAGVRRADTEAQVLEVPGRRAAIAEAVQLAAPGDVVALL 476 Query: 488 GKGHETGQRGAAETCPFDDRVELARALQVR 517 GKGHE GQ + PFDDR ELA AL+ R Sbjct: 477 GKGHEQGQEVGGQVHPFDDRTELAAALRAR 506 >tr|C2CNH9|C2CNH9_CORST Tax_Id=525268 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium striatum ATCC 6940] Length = 521 Score = 337 bits (864), Expect = 2e-90 Identities = 204/497 (41%), Positives = 260/497 (52%), Gaps = 22/497 (4%) Query: 35 GPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAG 94 G G+ + V+ +L ++ + +G LFAAL G HGA++AG + A A+LTD AG Sbjct: 12 GGGRVIGDDSVTVSACSLDSKAIAAGGLFAALPGTRVHGAQFAG---DTEAAAILTDEAG 68 Query: 95 VAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXX 154 + L PI++ + R+VLG +AA Y HP+ + E Sbjct: 69 LQHLQEAGERRPIIVVEDIRAVLGLIAAEIYEHPTEHLTVLGVTGTSGKTTTSYLLEAGL 128 Query: 155 XXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSL 214 T G RI+ +P+ LTTPEAP LQ + A M GV VVMEVSSHAL L Sbjct: 129 LHAGHKVGLIGTTGTRINREPVPTKLTTPEAPTLQELFARMRHEGVTHVVMEVSSHALEL 188 Query: 215 GRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXX 274 GRV GTQF V GFTNLS+DHLDFHP ME+YF AKA LFD A + V Sbjct: 189 GRVRGTQFDVGGFTNLSQDHLDFHPTMEDYFAAKAALFDGAQAASAAVICVDDDWGKRMA 248 Query: 275 XXXXXXXXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQH----------RVGIR 324 VS + + + + A++ +P G QH + Sbjct: 249 QQVAGKPLTLVSTTDEETAENTKQV----ISARQL-GTEPTGAQHVELSFSGETYSFELP 303 Query: 325 LPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPG 384 +PG++N+AN +A + VGV E G + +PGR+E I GQDF+A+VDYAHKP Sbjct: 304 MPGKFNIANAALAAGMAAAVGVDTETFLNGVERVAVPGRMESISRGQDFVAVVDYAHKPA 363 Query: 385 ALHSVLTALL----QPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGED 440 A+ +VL L + RL VV GAGG+RD KR MG AAE ADLVVVTDDNPR ED Sbjct: 364 AIAAVLDTLRGQLSETGGRLGVVVGAGGDRDSSKRPLMGAAAAERADLVVVTDDNPRSED 423 Query: 441 PAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAE 500 PAAIR ++ EIG R AAI V WA P D ++V GKGHE GQ E Sbjct: 424 PAAIRAAVMAGAQKASQTADIREIGSRAAAIDAVVEWAQPGDAIIVVGKGHEVGQIVGDE 483 Query: 501 TCPFDDRVELARALQVR 517 T FDDR E+ARAL + Sbjct: 484 TLHFDDREEVARALDTK 500 >tr|Q47QX4|Q47QX4_THEFY Tax_Id=269800 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Thermobifida fusca] Length = 534 Score = 335 bits (859), Expect = 9e-90 Identities = 211/490 (43%), Positives = 264/490 (53%), Gaps = 16/490 (3%) Query: 38 QAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAE 97 QA++V + VTGVT ++ V GDL+ A+ G HGA++A A GA AVLTD AG Sbjct: 47 QASSVDSVVVTGVTHDSRAVRPGDLYVAVQGQRVHGAKFAAQAARAGAAAVLTDPAGYDR 106 Query: 98 LTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXX 157 A A+ +P++ P+PRS LG +AA YGHP+ + E Sbjct: 107 --AAATRLPVITVPDPRSRLGDVAAWIYGHPARELLLIGTTGTSGKTTVSYLVESGLREA 164 Query: 158 XXXXXXXXTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRV 217 T+ IR+D I S LTTPEA L + A M ER V MEVSSHAL+LGRV Sbjct: 165 GMRTGLVGTVEIRVDDERIDSSLTTPEATELHGLFALMRERDVAGAAMEVSSHALALGRV 224 Query: 218 EGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCXXXXXXXXXXX 277 G ++ VA FTNLS+DHLDFH D+ +YFE KA LF P A+ VV Sbjct: 225 AGVRYDVAVFTNLSQDHLDFHADLHDYFETKARLFTPEF---AKVAVVNRDDSFGRTLID 281 Query: 278 XXXXXXXV-----SALGQPAS-WRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNV 331 + SA G A+ W ATD+ G F V P G+ +RLPG +NV Sbjct: 282 RITEQGAIPVTTFSATGDTAADWYATDVVLE-AGGSRFRVVGPGGMAMDASVRLPGPFNV 340 Query: 332 ANCLVALAILDVVGVSPEQASLGFRDIR-IPGRLERIDCGQDFLALVDYAHKPGALHSVL 390 AN + A+ L GV A G R +PGR+ER+D GQDF A+VDY+HKPGA+ +VL Sbjct: 341 ANAMAAIVALIEAGVPLPTAVAGVAAARGVPGRMERVDEGQDFTAIVDYSHKPGAIEAVL 400 Query: 391 TALLQ-PDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDIL 449 T+L + RL +V G GG+RD GKR MGE AA LAD V++TDDNPR EDP I +L Sbjct: 401 TSLRPITEGRLTIVVGCGGDRDRGKRPLMGEAAARLADAVILTDDNPRSEDPVTIITSML 460 Query: 450 XXXXXXXXXXXXXEI--GDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDR 507 DRR AI+ AV A P DVV+VAGKGHE GQ PFDDR Sbjct: 461 EGVAKVPVAQRARITVEPDRRTAIELAVTRAQPGDVVVVAGKGHERGQHVGDRILPFDDR 520 Query: 508 VELARALQVR 517 L A++ R Sbjct: 521 DVLREAIRAR 530 >tr|C2BNI4|C2BNI4_9CORY Tax_Id=525264 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium pseudogenitalium ATCC 33035] Length = 511 Score = 333 bits (855), Expect = 3e-89 Identities = 203/478 (42%), Positives = 254/478 (53%), Gaps = 14/478 (2%) Query: 45 IPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASS 104 + V+ L + + G LFAAL G HGA++A + A AVLTD AG+ LT + Sbjct: 22 VEVSACGLDSSRLPEGALFAALPGTRVHGAQFAR---DTKAGAVLTDAAGLDLLTEAQET 78 Query: 105 VPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXX 164 PIL+ + R+VLG ++A YGHP+ + E Sbjct: 79 RPILVVEDIRAVLGPISAEIYGHPTRELTVIGVTGTSGKTTTSYLLEAGLLHAGHSVGLI 138 Query: 165 XTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAV 224 T G RI+ +P+ LTTPEAP LQ + A M GV VVMEVSSHAL LGRV GT+FAV Sbjct: 139 GTTGTRINRTPVPTSLTTPEAPTLQELFARMKNEGVTHVVMEVSSHALELGRVRGTRFAV 198 Query: 225 AGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVC----XXXXXXXXXXXXXX 280 GFTNLS+DHLDFHP ME+YF+AKA LF A V+C Sbjct: 199 GGFTNLSQDHLDFHPTMEDYFQAKAKLFAGEQ--AAERAVLCIDDEWGERMRGVAKSAGH 256 Query: 281 XXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAI 340 V G A+ A + GAQE A+D G + LPG +N+AN +AL + Sbjct: 257 EVTTVDTQGAAATISARQTATEATGAQE-VALDYDGANFTFRLPLPGEFNIANACLALGM 315 Query: 341 LDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTALL----QP 396 VG P + G + +PGR+ERID GQDF+A+VDYAHKP A+ +VL L Sbjct: 316 ATAVGEDPAEFLSGVEKVAVPGRMERIDRGQDFVAVVDYAHKPAAIAAVLDTLRGQLEGT 375 Query: 397 DHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXX 456 R+ +V GAGG+RD KR MG AA ADL VVTDDNPR EDPA IR ++ Sbjct: 376 TGRVGIVVGAGGDRDSSKRPIMGAAAASRADLTVVTDDNPRSEDPATIRAAVVEGARDAA 435 Query: 457 XXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARAL 514 E+G R AI V WA P D V+V GKGHE GQ +T FDDR E+ARA+ Sbjct: 436 PQGDIREVGSRARAIDEVVDWAEPGDAVIVVGKGHEVGQLVNGKTLHFDDREEMARAI 493 >tr|C6RAX4|C6RAX4_9CORY Tax_Id=553206 SubName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium tuberculostearicum SK141] Length = 511 Score = 331 bits (849), Expect = 1e-88 Identities = 201/479 (41%), Positives = 256/479 (53%), Gaps = 14/479 (2%) Query: 45 IPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASS 104 + V+ L + + G LFAAL G HGA++A + A AVLTD AG+ LT + Sbjct: 22 VEVSACGLDSSRLPEGALFAALPGTRVHGAQFAR---DTKAGAVLTDAAGLDLLTKDQET 78 Query: 105 VPILIHPEPRSVLGGLAAAAYGHPSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXX 164 PI++ + R+VLG ++A YGHP+ + E Sbjct: 79 RPIVVVEDIRAVLGPISAEIYGHPTRDLTVIGVTGTSGKTTTSYLLEAGLLHAGHSVGLI 138 Query: 165 XTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAV 224 T G RI+ +P+ LTTPEAP LQ + A M GV VVMEVSSHAL LGRV GT+FAV Sbjct: 139 GTTGTRINRTPVPTSLTTPEAPTLQELFARMKNEGVTHVVMEVSSHALELGRVRGTRFAV 198 Query: 225 AGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVC----XXXXXXXXXXXXXX 280 GFTNLS+DHLDFHP ME+YF+AKA LF A V+C Sbjct: 199 GGFTNLSQDHLDFHPTMEDYFQAKAKLFAGEQ--AAERAVLCIDDEWGERMRGVAKSAGH 256 Query: 281 XXXXVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAI 340 V+ G A+ A + GAQE A++ G + LPG +N+AN +AL + Sbjct: 257 PVTTVATQGAAATISARQTATEATGAQE-VALNYDGADFTFRLPLPGEFNIANACLALGM 315 Query: 341 LDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTALL----QP 396 VG P + G + +PGR+ERID GQDF+A+VDYAHKP A+ +VL L Sbjct: 316 ATAVGEDPAEFLSGVEKVAVPGRMERIDRGQDFVAVVDYAHKPAAIAAVLDTLRGQLEGT 375 Query: 397 DHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDILXXXXXXX 456 R+ +V GAGG+RD KR MG AA ADL VVTDDNPR EDPA IR ++ Sbjct: 376 TGRVGIVVGAGGDRDSSKRPIMGAAAASRADLTVVTDDNPRSEDPATIRAAVVEGARDAA 435 Query: 457 XXXXXXEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARALQ 515 E+G R AI V WA P D V+V GKGHE GQ +T FDDR E+ARA++ Sbjct: 436 PEGDIREVGSRARAIDEVVDWAEPGDAVIVVGKGHEVGQLVNGKTLHFDDREEMARAIE 494 >tr|Q2JD55|Q2JD55_FRASC Tax_Id=106370 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Frankia sp.] Length = 544 Score = 331 bits (848), Expect = 2e-88 Identities = 221/516 (42%), Positives = 270/516 (52%), Gaps = 15/516 (2%) Query: 14 SATAGVRLPELVAQVGAVLAD--GPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGAST 71 +A A V P A G +D A T D+ V GVT + V GDL AAL GA T Sbjct: 35 AAVAPVPEPAAFAGAGHSPSDTHADTHADTDTDVIVHGVTHDSHAVRPGDLHAALPGAHT 94 Query: 72 HGARYAGVALERGAVAVLTDVAGVAELTAQA----SSVPILIHPEPRSVLGGLAAAAYGH 127 HGA +A A+ GAVAVLTD G + A VP+L+ +PR L +AA YG Sbjct: 95 HGAAFAAAAVAGGAVAVLTDAEGARRIAAMPPGPPGEVPVLVSDDPRRDLAPVAARIYGD 154 Query: 128 PSNRMXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSFLTTPEAPA 187 PS + + TI RI + S TTPEA Sbjct: 155 PSAALRLLGVTGTNGKTTTAFLLDAGLRAAGHTTGLIGTIETRIADERLASARTTPEASD 214 Query: 188 LQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEA 247 LQA+LA MVERGV MEVSSHAL+L R + FA A FTNLS+DHLDFH ME+YF A Sbjct: 215 LQALLATMVERGVGAATMEVSSHALALHRADALHFAGAVFTNLSQDHLDFHSSMEDYFAA 274 Query: 248 KAVLFDPHSLLRARTVVVCXXXXXXXXXXXXXXXXXXVS-ALGQPASWRATDIRSPGVGA 306 KA LFDP ART V ++ A+ PA W A D+ S G Sbjct: 275 KASLFDP-----ARTAVAVIGVADRWGRRLAERHPGAITFAVEGPADWTARDV-SYGPTG 328 Query: 307 QEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDI-RIPGRLE 365 A P G++ + + LPG +NVAN L ALA+L +GV P A+ G + +PGR+E Sbjct: 329 TLLRAEGPDGLRVDLSVPLPGAFNVANTLGALALLVAIGVPPATAAAGIGSLPGVPGRME 388 Query: 366 RIDCGQDFLALVDYAHKPGALHSVL-TALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAE 424 R+D GQ FLALVD+AH P A+ ++L T R+ VV G GG+RD GKR MG AA Sbjct: 389 RVDAGQPFLALVDFAHTPDAVTTLLETVRPLVKGRVIVVLGCGGDRDRGKRPLMGAAAAT 448 Query: 425 LADLVVVTDDNPRGEDPAAIRRDILXXXXXXXXXXXXXEIGDRRAAIQYAVAWAGPDDVV 484 LAD+ ++T+DNPR EDPA I +L DR AAI AVA AGP D V Sbjct: 449 LADVAILTNDNPRSEDPAEILAQMLAGVTALSASATVLVEPDRAAAIAAAVAEAGPQDAV 508 Query: 485 LVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 +VAGKGHE+GQ A PFDDRV L AL + R Sbjct: 509 VVAGKGHESGQEQAGVVTPFDDRVALRAALSSVERR 544 Database: Amellifera_nr Posted date: Jan 15, 2010 5:10 AM Number of letters in database: 3,808,957,724 Number of sequences in database: 11,153,314 Lambda K H 0.320 0.136 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11153314 Number of Hits to DB: 3,460,232,140 Number of extensions: 131978009 Number of successful extensions: 377547 Number of sequences better than 10.0: 3964 Number of HSP's gapped: 374422 Number of HSP's successfully gapped: 5355 Length of query: 530 Length of database: 3,808,957,724 Length adjustment: 142 Effective length of query: 388 Effective length of database: 2,225,187,136 Effective search space: 863372608768 Effective search space used: 863372608768 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 83 (36.6 bits)