BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ML1091
         (329 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,153,314 sequences; 3,808,957,724 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|P50917|MDH_MYCLE Tax_Id=1769 (mdh)RecName: Full=Malate dehydr...   584   e-165
tr|B8ZR02|B8ZR02_MYCLB Tax_Id=561304 (mdh)RecName: Full=Malate d...   584   e-165
sp|P61976|MDH_MYCPA Tax_Id=1770 (mdh)RecName: Full=Malate dehydr...   521   e-146
sp|A0QCI6|MDH_MYCA1 Tax_Id=243243 (mdh)RecName: Full=Malate dehy...   520   e-145
sp|B2HRH5|MDH_MYCMM Tax_Id=216594 (mdh)RecName: Full=Malate dehy...   518   e-145
sp|A0PVV1|MDH_MYCUA Tax_Id=362242 (mdh)RecName: Full=Malate dehy...   516   e-144
sp|P0A5J6|MDH_MYCTU Tax_Id=1773 (mdh)RecName: Full=Malate dehydr...   515   e-144
sp|A5U1T8|MDH_MYCTA Tax_Id=419947 (mdh)RecName: Full=Malate dehy...   515   e-144
sp|C1AMN4|MDH_MYCBT Tax_Id=561275 (mdh)RecName: Full=Malate dehy...   515   e-144
sp|A1KI28|MDH_MYCBP Tax_Id=410289 (mdh)RecName: Full=Malate dehy...   515   e-144
sp|P0A5J7|MDH_MYCBO Tax_Id=1765 (mdh)RecName: Full=Malate dehydr...   515   e-144
tr|C6DUD1|C6DUD1_MYCTK Tax_Id=478434 RecName: Full=Malate dehydr...   515   e-144
tr|A4KGG4|A4KGG4_MYCTU Tax_Id=395095 RecName: Full=Malate dehydr...   515   e-144
tr|A5WLR9|A5WLR9_MYCTF Tax_Id=336982 RecName: Full=Malate dehydr...   513   e-143
sp|A1SMP3|MDH_NOCSJ Tax_Id=196162 (mdh)RecName: Full=Malate dehy...   498   e-139
tr|C1WJR2|C1WJR2_9ACTO Tax_Id=479435 RecName: Full=Malate dehydr...   462   e-128
sp|A1R2B5|MDH_ARTAT Tax_Id=290340 (mdh)RecName: Full=Malate dehy...   451   e-125
tr|A3TQD8|A3TQD8_9MICO Tax_Id=313589 RecName: Full=Malate dehydr...   445   e-123
tr|C7NF16|C7NF16_KYTSD Tax_Id=478801 RecName: Full=Malate dehydr...   438   e-121
tr|C7QGU6|C7QGU6_CATAD Tax_Id=479433 RecName: Full=Malate dehydr...   422   e-116
sp|Q6A6Z5|MDH_PROAC Tax_Id=1747 (mdh)RecName: Full=Malate dehydr...   421   e-116
tr|C2A4C6|C2A4C6_THECU Tax_Id=471852 RecName: Full=Malate dehydr...   419   e-115
sp|Q9K3J3|MDH_STRCO Tax_Id=1902 (mdh)RecName: Full=Malate dehydr...   418   e-115
tr|B5H2X3|B5H2X3_STRCL Tax_Id=443255 RecName: Full=Malate dehydr...   417   e-114
tr|C1YN79|C1YN79_NOCDA Tax_Id=446468 RecName: Full=Malate dehydr...   415   e-114
tr|C6WLQ8|C6WLQ8_ACTMD Tax_Id=446462 RecName: Full=Malate dehydr...   414   e-114
sp|B1W3N4|MDH_STRGG Tax_Id=455632 (mdh)RecName: Full=Malate dehy...   411   e-113
sp|Q82HS2|MDH_STRAW Tax_Id=33903 (mdh)RecName: Full=Malate dehyd...   410   e-113
tr|C8XK71|C8XK71_NAKMY Tax_Id=479431 SubName: Full=Malate dehydr...   410   e-113
tr|B5HVE5|B5HVE5_9ACTO Tax_Id=463191 RecName: Full=Malate dehydr...   409   e-112
sp|B2GKC8|MDH_KOCRD Tax_Id=378753 (mdh)RecName: Full=Malate dehy...   408   e-112
tr|C9YTG2|C9YTG2_STRSW Tax_Id=680198 (mdh)SubName: Full=Malate d...   407   e-112
sp|Q47TT4|MDH_THEFY Tax_Id=269800 (mdh)RecName: Full=Malate dehy...   406   e-111
tr|C9N8P8|C9N8P8_9ACTO Tax_Id=591167 SubName: Full=Malate dehydr...   406   e-111
tr|C7MV61|C7MV61_SACVD Tax_Id=471857 RecName: Full=Malate dehydr...   405   e-111
sp|A4FFX3|MDH_SACEN Tax_Id=405948 (mdh)RecName: Full=Malate dehy...   404   e-110
tr|C5BZS1|C5BZS1_BEUC1 Tax_Id=471853 RecName: Full=Malate dehydr...   400   e-110
tr|C1RNE1|C1RNE1_9CELL Tax_Id=446466 RecName: Full=Malate dehydr...   399   e-109
sp|Q2J7E7|MDH_FRASC Tax_Id=106370 (mdh)RecName: Full=Malate dehy...   398   e-109
sp|Q0RE66|MDH_FRAAA Tax_Id=326424 (mdh)RecName: Full=Malate dehy...   396   e-108
tr|C4EH55|C4EH55_STRRS Tax_Id=479432 RecName: Full=Malate dehydr...   391   e-107
tr|C9K9P2|C9K9P2_9MICO Tax_Id=446469 SubName: Full=Malate dehydr...   388   e-106
sp|C1B155|MDH_RHOOB Tax_Id=632772 (mdh)RecName: Full=Malate dehy...   387   e-105
tr|C1XYV8|C1XYV8_9DEIN Tax_Id=526227 RecName: Full=Malate dehydr...   383   e-104
sp|Q0S365|MDH_RHOSR Tax_Id=101510 (mdh)RecName: Full=Malate dehy...   377   e-102
tr|C0ZZ60|C0ZZ60_RHOE4 Tax_Id=234621 (mdh)RecName: Full=Malate d...   374   e-102
tr|C3JNL4|C3JNL4_RHOER Tax_Id=596309 RecName: Full=Malate dehydr...   374   e-102
tr|C1XNQ5|C1XNQ5_MEIRU Tax_Id=504728 RecName: Full=Malate dehydr...   371   e-101
sp|Q5YTI1|MDH_NOCFA Tax_Id=37329 (mdh)RecName: Full=Malate dehyd...   369   e-100
tr|C0W8W1|C0W8W1_9ACTO Tax_Id=525246 (mdh)RecName: Full=Malate d...   368   e-100

>sp|P50917|MDH_MYCLE Tax_Id=1769 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium leprae]
          Length = 329

 Score =  584 bits (1506), Expect = e-165
 Identities = 301/329 (91%), Positives = 302/329 (91%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +SPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD
Sbjct: 1   MSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR
Sbjct: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG
Sbjct: 241 ASAASATIDAARDWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           IDDFSRGRIDKSTAELADERMAVKQLGLI
Sbjct: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329


>tr|B8ZR02|B8ZR02_MYCLB Tax_Id=561304 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium leprae]
          Length = 329

 Score =  584 bits (1506), Expect = e-165
 Identities = 301/329 (91%), Positives = 302/329 (91%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +SPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD
Sbjct: 1   MSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR
Sbjct: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG
Sbjct: 241 ASAASATIDAARDWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           IDDFSRGRIDKSTAELADERMAVKQLGLI
Sbjct: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329


>sp|P61976|MDH_MYCPA Tax_Id=1770 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium
           paratuberculosis]
          Length = 329

 Score =  521 bits (1342), Expect = e-146
 Identities = 268/329 (81%), Positives = 283/329 (86%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPALKALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALKALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIGADPNK+FDG NLALLVGARPRGPGMER DLLEANGAIFTAQGKALN V
Sbjct: 61  CAFPLLSGVEIGADPNKIFDGANLALLVGARPRGPGMERSDLLEANGAIFTAQGKALNEV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DIRVGVTGNPANTNALIAM+NAPDIPRERFSALTRLDHNRAI+QLA KTG+ VTDI+
Sbjct: 121 AADDIRVGVTGNPANTNALIAMSNAPDIPRERFSALTRLDHNRAISQLAKKTGAKVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVVGDQ WIE+ FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDIFHAEVKGKNAAEVVGDQNWIENDFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP G+WVSMAV+SDGSYGVPEGLISSFPVTT DGDWTIV+GL 
Sbjct: 241 ASAASATTDAARDWLLGTPAGDWVSMAVISDGSYGVPEGLISSFPVTTKDGDWTIVQGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSR RIDK+TAELADER AV QLGLI
Sbjct: 301 IDEFSRSRIDKTTAELADERNAVTQLGLI 329


>sp|A0QCI6|MDH_MYCA1 Tax_Id=243243 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium avium]
          Length = 329

 Score =  520 bits (1339), Expect = e-145
 Identities = 268/329 (81%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPALKALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALKALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIGADPNK+FDG NLALLVGARPRGPGMER DLLEANGAIFTAQGKALN V
Sbjct: 61  CAFPLLSGVEIGADPNKIFDGANLALLVGARPRGPGMERSDLLEANGAIFTAQGKALNEV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DIRVGVTGNPANTNALIAM+NAPDIPRERFSALTRLDHNRAI+QLA KTG+ VTDI 
Sbjct: 121 AADDIRVGVTGNPANTNALIAMSNAPDIPRERFSALTRLDHNRAISQLAKKTGAKVTDIT 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVVGDQ WIE+ FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDIFHAEVKGKNAAEVVGDQNWIENDFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP G+WVSMAV+SDGSYGVPEGLISSFPVTT DGDWTIV+GL 
Sbjct: 241 ASAASATTDAARDWLLGTPAGDWVSMAVISDGSYGVPEGLISSFPVTTKDGDWTIVQGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSR RIDK+TAELADER AV QLGLI
Sbjct: 301 IDEFSRSRIDKTTAELADERNAVTQLGLI 329


>sp|B2HRH5|MDH_MYCMM Tax_Id=216594 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium marinum]
          Length = 329

 Score =  518 bits (1334), Expect = e-145
 Identities = 266/329 (80%), Positives = 283/329 (86%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPALKALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALKALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+D NK+FDG NLALLVGARPRGPGMER DLLEANGAIFTAQGKALN V
Sbjct: 61  CAFPLLSGVEIGSDANKIFDGANLALLVGARPRGPGMERSDLLEANGAIFTAQGKALNEV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG AVTDI+
Sbjct: 121 AADDIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGVAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIE+YFIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVKGKNAAEVVNDQAWIEEYFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAV+SDGSYGVPEGLISSFPVTT DG+W+IV+GL 
Sbjct: 241 ASAASATVDAARSWLLGTPADDWVSMAVLSDGSYGVPEGLISSFPVTTKDGNWSIVKGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDK+TAELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKTTAELADERKAVTELGLI 329


>sp|A0PVV1|MDH_MYCUA Tax_Id=362242 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium ulcerans]
          Length = 329

 Score =  516 bits (1329), Expect = e-144
 Identities = 265/329 (80%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPALKALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALKALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+D NK+FDG NLALLVGARPRGPGMER DLLEANGAIFTAQGKALN V
Sbjct: 61  CAFPLLSGVEIGSDANKIFDGANLALLVGARPRGPGMERSDLLEANGAIFTAQGKALNEV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG AVTDI+
Sbjct: 121 AADDIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGVAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIE+YFIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVKGKNAAEVVNDQAWIEEYFIPTVAKRGATIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAV+SDGSYGVPEGLISSFPVTT DG+W+IV+GL 
Sbjct: 241 ASAASASVDAARSWLLGTPADDWVSMAVLSDGSYGVPEGLISSFPVTTKDGNWSIVKGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDK+ AELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKTAAELADERKAVTELGLI 329


>sp|P0A5J6|MDH_MYCTU Tax_Id=1773 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium tuberculosis]
          Length = 329

 Score =  515 bits (1327), Expect = e-144
 Identities = 266/329 (80%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPAL+ALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+DP K+FDGV+LALLVGARPRG GMER DLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 121 AADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIED FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAVVSDGSYGVPEGLISSFPVTT  G+WTIV GL 
Sbjct: 241 ASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDKSTAELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKSTAELADERSAVTELGLI 329


>sp|A5U1T8|MDH_MYCTA Tax_Id=419947 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium tuberculosis]
          Length = 329

 Score =  515 bits (1327), Expect = e-144
 Identities = 266/329 (80%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPAL+ALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+DP K+FDGV+LALLVGARPRG GMER DLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 121 AADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIED FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAVVSDGSYGVPEGLISSFPVTT  G+WTIV GL 
Sbjct: 241 ASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDKSTAELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKSTAELADERSAVTELGLI 329


>sp|C1AMN4|MDH_MYCBT Tax_Id=561275 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium bovis]
          Length = 329

 Score =  515 bits (1327), Expect = e-144
 Identities = 266/329 (80%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPAL+ALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+DP K+FDGV+LALLVGARPRG GMER DLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 121 AADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIED FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAVVSDGSYGVPEGLISSFPVTT  G+WTIV GL 
Sbjct: 241 ASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDKSTAELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKSTAELADERSAVTELGLI 329


>sp|A1KI28|MDH_MYCBP Tax_Id=410289 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium bovis]
          Length = 329

 Score =  515 bits (1327), Expect = e-144
 Identities = 266/329 (80%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPAL+ALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+DP K+FDGV+LALLVGARPRG GMER DLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 121 AADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIED FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAVVSDGSYGVPEGLISSFPVTT  G+WTIV GL 
Sbjct: 241 ASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDKSTAELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKSTAELADERSAVTELGLI 329


>sp|P0A5J7|MDH_MYCBO Tax_Id=1765 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium bovis]
          Length = 329

 Score =  515 bits (1327), Expect = e-144
 Identities = 266/329 (80%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPAL+ALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+DP K+FDGV+LALLVGARPRG GMER DLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 121 AADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIED FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAVVSDGSYGVPEGLISSFPVTT  G+WTIV GL 
Sbjct: 241 ASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDKSTAELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKSTAELADERSAVTELGLI 329


>tr|C6DUD1|C6DUD1_MYCTK Tax_Id=478434 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium tuberculosis]
          Length = 329

 Score =  515 bits (1327), Expect = e-144
 Identities = 266/329 (80%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPAL+ALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+DP K+FDGV+LALLVGARPRG GMER DLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 121 AADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIED FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAVVSDGSYGVPEGLISSFPVTT  G+WTIV GL 
Sbjct: 241 ASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDKSTAELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKSTAELADERSAVTELGLI 329


>tr|A4KGG4|A4KGG4_MYCTU Tax_Id=395095 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium tuberculosis
           str. Haarlem]
          Length = 329

 Score =  515 bits (1327), Expect = e-144
 Identities = 266/329 (80%), Positives = 282/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPAL+ALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+DP K+FDGV+LALLVGARPRG GMER DLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 121 AADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIED FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAVVSDGSYGVPEGLISSFPVTT  G+WTIV GL 
Sbjct: 241 ASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSRGRIDKSTAELADER AV +LGLI
Sbjct: 301 IDEFSRGRIDKSTAELADERSAVTELGLI 329


>tr|A5WLR9|A5WLR9_MYCTF Tax_Id=336982 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Mycobacterium tuberculosis]
          Length = 329

 Score =  513 bits (1320), Expect = e-143
 Identities = 265/329 (80%), Positives = 281/329 (85%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEIEPAL+ALEGVVMELDD
Sbjct: 1   MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL+GVEIG+DP K+FDGV+LALLVGARPRG GMER DLLEANGAIFTAQGKALNAV
Sbjct: 61  CAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 121 AADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPD+FHAE+ GKNAAEVV DQAWIED FIPTVAK              
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WLLGTP  +WVSMAVVSDGSYGVPEGLISSFPVTT  G+WTIV GL 
Sbjct: 241 ASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FS GRIDKSTAELADER AV +LGLI
Sbjct: 301 IDEFSGGRIDKSTAELADERSAVTELGLI 329


>sp|A1SMP3|MDH_NOCSJ Tax_Id=196162 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Nocardioides sp.]
          Length = 328

 Score =  498 bits (1283), Expect = e-139
 Identities = 259/329 (78%), Positives = 276/329 (83%), Gaps = 1/329 (0%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  PLKVAVTGAAGQIGYSLLFRLASGSLLG DRPIELRLLEI PALKALEGVVMELDD
Sbjct: 1   MSSTPLKVAVTGAAGQIGYSLLFRLASGSLLG-DRPIELRLLEITPALKALEGVVMELDD 59

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF  LAGV+IG D  ++FDGVNLALLVGARPRGPGMERGDLL ANGAIFTAQGKALN V
Sbjct: 60  CAFPNLAGVQIGDDAEQIFDGVNLALLVGARPRGPGMERGDLLSANGAIFTAQGKALNKV 119

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+R+GVTGNPANTNALIAMTNAPDIP+ RFSALTRLDHNRAI+QLA KTG+AVTDI+
Sbjct: 120 AADDVRIGVTGNPANTNALIAMTNAPDIPQARFSALTRLDHNRAISQLAAKTGAAVTDIK 179

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSATQYPDVFHAEIGG+NAAEVVGDQ WIE  FIPTVAK              
Sbjct: 180 KMTIWGNHSATQYPDVFHAEIGGRNAAEVVGDQDWIESTFIPTVAKRGAAIIEARGSSSA 239

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        WL G+ + +WVSMAVVSDGSYGVPEGLISSFPVTT DGDW IV+GL 
Sbjct: 240 ASAASATIDAARDWLFGSADADWVSMAVVSDGSYGVPEGLISSFPVTTKDGDWEIVQGLE 299

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           IDDFSR +ID STAELADER AVK+LGLI
Sbjct: 300 IDDFSRAKIDASTAELADEREAVKELGLI 328


>tr|C1WJR2|C1WJR2_9ACTO Tax_Id=479435 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Kribbella flavida DSM 17836]
          Length = 325

 Score =  462 bits (1189), Expect = e-128
 Identities = 237/324 (73%), Positives = 263/324 (81%)

Query: 6   LKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFLL 65
           +KVAVTGAAGQIGYSLLFR+ASG+LLG D P+ELRLLEI PALKALEGVVMELDDCAF  
Sbjct: 1   MKVAVTGAAGQIGYSLLFRIASGALLGPDTPVELRLLEITPALKALEGVVMELDDCAFPT 60

Query: 66  LAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAADI 125
           LA VEIG DPN +FDG N+ALLVGARPR  GMERGDLLEANGAIFT QGKALN  AA DI
Sbjct: 61  LAKVEIGDDPNTIFDGANVALLVGARPRTKGMERGDLLEANGAIFTGQGKALNDHAADDI 120

Query: 126 RVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTIW 185
           RV VTGNPANTNALIA +NAPDIP ERFSALTRLDHNRA+AQLA KTG++V D++K+TIW
Sbjct: 121 RVTVTGNPANTNALIAKSNAPDIPAERFSALTRLDHNRALAQLAKKTGTSVNDLKKLTIW 180

Query: 186 GNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXXX 245
           GNHSATQYPD+FHAE+ GKNAAEVV DQ W+E+ FIPTV K                   
Sbjct: 181 GNHSATQYPDIFHAEVAGKNAAEVVNDQTWLENDFIPTVQKRGAAIIEARGASSAASAAA 240

Query: 246 XXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDFS 305
                   WL G+ +G+W+SMAVVSDGSYGVPEGLISSFPV T DG+W IV+GL I+DFS
Sbjct: 241 ATIDHTRDWLRGSADGDWLSMAVVSDGSYGVPEGLISSFPVITKDGNWEIVQGLEINDFS 300

Query: 306 RGRIDKSTAELADERMAVKQLGLI 329
           RGRID S AELA+ER AV+QLGLI
Sbjct: 301 RGRIDASAAELAEERDAVQQLGLI 324


>sp|A1R2B5|MDH_ARTAT Tax_Id=290340 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Arthrobacter aurescens]
          Length = 328

 Score =  451 bits (1160), Expect = e-125
 Identities = 229/325 (70%), Positives = 256/325 (78%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+K+AVTGAAGQIGYSLLFR+ASG+L G D P++LRLLEI PALKALEGVVMELDDCAF 
Sbjct: 4   PIKIAVTGAAGQIGYSLLFRIASGALFGGDTPVQLRLLEITPALKALEGVVMELDDCAFP 63

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
            L  VEIG D + +FDGV LALLVGARPR  GMERGDLL ANGAIFTAQGKALN VAA D
Sbjct: 64  ALDSVEIGDDADHIFDGVTLALLVGARPRSKGMERGDLLSANGAIFTAQGKALNRVAADD 123

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +R+GVTGNPANTNALIAM+NAPDIP  RFSALTRLDHNRAI QLA KT + V DIRKMT+
Sbjct: 124 VRIGVTGNPANTNALIAMSNAPDIPASRFSALTRLDHNRAIGQLAAKTHARVGDIRKMTV 183

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHAE+ G+NAAEVV DQ WIE+ FIPTVA                   
Sbjct: 184 WGNHSATQYPDIFHAEVAGRNAAEVVNDQDWIENEFIPTVAGRGAAIIEARGASSAASAA 243

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    WLLGTPEG+WVSMAV SDGSYGVPEGL+ S+PVTT+ G+W IV GL ++DF
Sbjct: 244 SATIDAARDWLLGTPEGDWVSMAVASDGSYGVPEGLMYSYPVTTSGGNWEIVEGLEVNDF 303

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR ++D + AEL DER AV  LGLI
Sbjct: 304 SRRKMDATAAELFDERAAVANLGLI 328


>tr|A3TQD8|A3TQD8_9MICO Tax_Id=313589 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Janibacter sp. HTCC2649]
          Length = 333

 Score =  445 bits (1144), Expect = e-123
 Identities = 233/333 (69%), Positives = 259/333 (77%), Gaps = 4/333 (1%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+KVAVTGAAGQIGYSLLFR+ASG+LLG D P+ELRLLEI PALKALEGVVMELDD
Sbjct: 1   MSQTPVKVAVTGAAGQIGYSLLFRIASGALLGPDVPVELRLLEITPALKALEGVVMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF  LAGV+IG D   VFDGVN ALLVGARPRGPGMERGDLL ANG IF  QGKALN V
Sbjct: 61  CAFPTLAGVQIGDDAETVFDGVNHALLVGARPRGPGMERGDLLSANGGIFAPQGKALNKV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+ + VTGNPANTNALIAM+NAPDIP  +FSALTRLDHNRAI+QLA K G  VT+I+
Sbjct: 121 AADDVHITVTGNPANTNALIAMSNAPDIPTSQFSALTRLDHNRAISQLAAKLGVPVTEIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGD----QAWIEDYFIPTVAKXXXXXXXXXX 236
           KMTIWGNHSATQYPD+FHAE+ GKNAA++V +     +W+ D FIPTVAK          
Sbjct: 181 KMTIWGNHSATQYPDLFHAEVSGKNAAQLVRNDTDGDSWLADTFIPTVAKRGAAIIEARG 240

Query: 237 XXXXXXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIV 296
                            W+ GT EG+WVSMAV SDGSYGV EGLISSFPVT  DG W+IV
Sbjct: 241 ASSAASAASATIDHARTWVEGTAEGDWVSMAVRSDGSYGVQEGLISSFPVTVKDGQWSIV 300

Query: 297 RGLGIDDFSRGRIDKSTAELADERMAVKQLGLI 329
           +GL ID+FSRGRID S AELA+ER AVK LGLI
Sbjct: 301 QGLTIDEFSRGRIDASVAELAEERDAVKGLGLI 333


>tr|C7NF16|C7NF16_KYTSD Tax_Id=478801 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Kytococcus sedentarius]
          Length = 342

 Score =  438 bits (1127), Expect = e-121
 Identities = 225/326 (69%), Positives = 256/326 (78%)

Query: 4   RPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAF 63
           +P+KVAVTGAAGQIGYSLLFR+ASG LLG D P++LRLLEI PAL+ALEGVVMELDD AF
Sbjct: 15  QPVKVAVTGAAGQIGYSLLFRIASGELLGPDTPVQLRLLEITPALEALEGVVMELDDSAF 74

Query: 64  LLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAA 123
            LL+GVEIG D N +FDG N+ALLVGARPRG GMER DLLEANG IFT QGKALN  AA 
Sbjct: 75  PLLSGVEIGDDANTIFDGANVALLVGARPRGKGMERSDLLEANGQIFTGQGKALNDNAAD 134

Query: 124 DIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMT 183
           DIRV VTGNPANTNALI M NAPDIP ERFSALTRLDHNRA+AQLA K G ++ DI++MT
Sbjct: 135 DIRVTVTGNPANTNALITMNNAPDIPAERFSALTRLDHNRALAQLAKKAGVSINDIQRMT 194

Query: 184 IWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXX 243
           IWGNHSATQYPD+FHA I G+NAAEVV DQ W+E+ FIPTV++                 
Sbjct: 195 IWGNHSATQYPDIFHATINGENAAEVVDDQQWLENDFIPTVSQRGAAIIEARGSSSAASA 254

Query: 244 XXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDD 303
                     WL GT EGNW SMAV SDGSYGVPEGLISSFPVTT DG++ IV+GL I++
Sbjct: 255 ASATIDHTRTWLSGTAEGNWTSMAVRSDGSYGVPEGLISSFPVTTKDGEYEIVQGLEINE 314

Query: 304 FSRGRIDKSTAELADERMAVKQLGLI 329
           FS+G+ID + AEL++ER  V+  GLI
Sbjct: 315 FSQGKIDATVAELSEERDTVRAKGLI 340


>tr|C7QGU6|C7QGU6_CATAD Tax_Id=479433 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Catenulispora acidiphila]
          Length = 329

 Score =  422 bits (1084), Expect = e-116
 Identities = 218/329 (66%), Positives = 251/329 (76%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+ V VTGAAGQIGY+LLFR+ASG LLG D P++L LLEI  A+KA EG  MEL D
Sbjct: 1   MSRTPVNVTVTGAAGQIGYALLFRIASGHLLGPDVPVKLNLLEIPQAVKAAEGTAMELID 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
            AF LLAG++I  +P   F G N+ALLVGARPR  GMERGDLLEANG IF  QG+A+NA 
Sbjct: 61  SAFPLLAGIDIHDNPKDGFTGANVALLVGARPRTAGMERGDLLEANGGIFKPQGEAINAH 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DI+V V GNPANTNALIA  +APD+P+ RF+A+TRLDHNRA+ QLA KTG+ V+DI 
Sbjct: 121 AADDIKVLVVGNPANTNALIAAAHAPDVPKSRFTAMTRLDHNRALGQLALKTGAPVSDIT 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
            MTIWGNHSATQYPDVFHA+IGGKNAAEVVGDQAWIE  FIPTVAK              
Sbjct: 181 NMTIWGNHSATQYPDVFHAKIGGKNAAEVVGDQAWIEKDFIPTVAKRGAAIIEARGFSSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        W+ GT EG+W SM VVSDGSYGVPEGL+SSFPVTT++G+WTIV+GL 
Sbjct: 241 ASAANAALNHVNTWVNGTAEGDWTSMGVVSDGSYGVPEGLVSSFPVTTSNGEWTIVQGLD 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           ID+FSR RID S AELA+ER AV+QLGLI
Sbjct: 301 IDEFSRTRIDASVAELAEERDAVRQLGLI 329


>sp|Q6A6Z5|MDH_PROAC Tax_Id=1747 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Propionibacterium acnes]
          Length = 327

 Score =  421 bits (1082), Expect = e-116
 Identities = 225/325 (69%), Positives = 246/325 (75%), Gaps = 2/325 (0%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+K+AVTGAAGQI YSLLFR+ASGSLLG D PIELRLLEI PALKALEGVVMELDDCAF 
Sbjct: 5   PVKIAVTGAAGQICYSLLFRIASGSLLG-DTPIELRLLEITPALKALEGVVMELDDCAFG 63

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
            L  +EIG DP KVFDGVN A LVGA PR  GMER DLL  NGAIFTAQGKALN VAA D
Sbjct: 64  NLVNIEIGDDPKKVFDGVNAAFLVGAMPRKAGMERSDLLTKNGAIFTAQGKALNDVAADD 123

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +RV VTGNPANTNALIA TNA DIP   F+ALTRLDHNRA  QLA KTG  V D+R MTI
Sbjct: 124 VRVLVTGNPANTNALIAATNAVDIPNNHFAALTRLDHNRAKTQLARKTGKTVNDVRHMTI 183

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHS+TQYPDVFHAE+ G+ A  +V ++AWIE+ FIPTVAK                  
Sbjct: 184 WGNHSSTQYPDVFHAEVAGQKATNLV-NEAWIENEFIPTVAKRGAAIIDARGASSAASAA 242

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+  TPEG+WVSMA+ SDGSYGVPEGLISSFPVT T+G   IV+GL IDDF
Sbjct: 243 NATVECMRDWMGSTPEGDWVSMAIPSDGSYGVPEGLISSFPVTITNGKVEIVQGLDIDDF 302

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR +ID S  ELADER AVK+LGLI
Sbjct: 303 SRAKIDASAKELADERDAVKELGLI 327


>tr|C2A4C6|C2A4C6_THECU Tax_Id=471852 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Thermomonospora curvata DSM
           43183]
          Length = 329

 Score =  419 bits (1078), Expect = e-115
 Identities = 214/325 (65%), Positives = 247/325 (76%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P+ LRLLEI  A+KA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGQLLGPDVPVRLRLLEIPQAIKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LLAG++I  D    FDG N+ALLVGARPR  GMER DLLEANG IF  QG+A+NA AA D
Sbjct: 65  LLAGIDITDDLKTAFDGANIALLVGARPRTKGMERRDLLEANGGIFKPQGEAINAHAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           I+V V GNPANTNALIA ++APD+P +RF+A+TRLDHNRAIAQL+ K G  V+ I+KMTI
Sbjct: 125 IKVLVVGNPANTNALIARSHAPDVPADRFTAMTRLDHNRAIAQLSKKAGVPVSSIKKMTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHAEI G+NAAEVVGDQ W+E+ FIPTVAK                  
Sbjct: 185 WGNHSATQYPDLFHAEIDGRNAAEVVGDQEWLENDFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GTPEG+W SMAVVSDGSYGVPEGL+SSFPVT + G W IV+GL ID+F
Sbjct: 245 SAAIDHIHTWVNGTPEGDWTSMAVVSDGSYGVPEGLVSSFPVTCSGGKWEIVQGLEIDEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SRG+ID S AEL +ER AV+ LGLI
Sbjct: 305 SRGKIDASVAELVEERDAVRNLGLI 329


>sp|Q9K3J3|MDH_STRCO Tax_Id=1902 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Streptomyces coelicolor]
          Length = 329

 Score =  418 bits (1074), Expect = e-115
 Identities = 211/325 (64%), Positives = 242/325 (74%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P++LRLLEI PALKA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGQLLGADVPVKLRLLEITPALKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G+EI  DPN  FDG N+ALLVGARPR  GMERGDLLEANG IF  QGKA+N  AA D
Sbjct: 65  LLQGIEITDDPNVAFDGANVALLVGARPRTKGMERGDLLEANGGIFKPQGKAINDHAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           I+V V GNPANTNALIA   APD+P ERF+A+TRLDHNRA+ QLA KTGS V DI+++TI
Sbjct: 125 IKVLVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRALTQLAKKTGSTVADIKRLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHA + GKNAAE V D+ W+ D FIPTVAK                  
Sbjct: 185 WGNHSATQYPDIFHATVAGKNAAETVNDEKWLADEFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT EG+W SM + SDGSYGVPEG+ISSFPVTT DG + IV+GL I++F
Sbjct: 245 NAAIDHVYTWVNGTAEGDWTSMGIPSDGSYGVPEGIISSFPVTTKDGSYEIVQGLDINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  EL++ER AV+ LGLI
Sbjct: 305 SRARIDASVKELSEEREAVRGLGLI 329


>tr|B5H2X3|B5H2X3_STRCL Tax_Id=443255 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Streptomyces clavuligerus
           ATCC 27064]
          Length = 329

 Score =  417 bits (1071), Expect = e-114
 Identities = 213/325 (65%), Positives = 244/325 (75%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P++LRLLEI PAL A +G  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGHLLGPDVPVKLRLLEITPALGAAQGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G++I  DPN  FDG N+ALLVGARPR  GMERGDLLEANG IF  QGKA+N  AA D
Sbjct: 65  LLRGIDITDDPNVAFDGANVALLVGARPRTKGMERGDLLEANGGIFKPQGKAINDHAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           I+V V GNPANTNALIA   APD+P ERF+A+TRLDHNRA++QLA KTG+ V DI+++TI
Sbjct: 125 IKVLVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRALSQLAAKTGTTVADIKRLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHAEI GKNAAEVV DQAW+ D FIPTVAK                  
Sbjct: 185 WGNHSATQYPDIFHAEIAGKNAAEVVNDQAWLADTFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT EG+W SM + SDGSYGVPEGLISSFPVT  DG + IV+GL I++F
Sbjct: 245 NAAIDHVHTWVNGTAEGDWTSMGIPSDGSYGVPEGLISSFPVTVKDGRYEIVQGLEINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  ELA+ER AV+ LGLI
Sbjct: 305 SRTRIDASVQELAEERDAVRALGLI 329


>tr|C1YN79|C1YN79_NOCDA Tax_Id=446468 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Nocardiopsis dassonvillei
           subsp. dassonvillei DSM 43111]
          Length = 329

 Score =  415 bits (1067), Expect = e-114
 Identities = 209/329 (63%), Positives = 244/329 (74%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+ V VTGAAGQIGY+LLFR+ASG LLG D P++LRLLEI  A+KA EG  MELDD
Sbjct: 1   MSKAPVNVTVTGAAGQIGYALLFRIASGQLLGADTPVKLRLLEIPQAVKAAEGTAMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LL G++I  D  + F G N+ALLVGARPRG GMERGDLLEANG IF  QG+A+NA 
Sbjct: 61  CAFPLLQGIDIFDDATQAFQGANVALLVGARPRGKGMERGDLLEANGGIFKPQGEAINAG 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DIRV V GNPANTNALIA ++APD+P ERF+A+TRLDHNRA+ QLA K   ++ DI+
Sbjct: 121 AADDIRVLVVGNPANTNALIAQSHAPDVPAERFTAMTRLDHNRALTQLAKKLDVSINDIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           K+TIWGNHSATQYPDVFHAE+ G NAA+ VGDQAW+E+ FIPTVAK              
Sbjct: 181 KLTIWGNHSATQYPDVFHAEVNGANAAKAVGDQAWLENDFIPTVAKRGAAIIEARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        W+ GTPEG+W S A+ SDGSYGVPEG+ISSFPV +  G W IV+GL 
Sbjct: 241 ASAANAAVDHVYDWVNGTPEGDWTSAAIPSDGSYGVPEGIISSFPVVSRGGRWEIVQGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           IDDFSR RID S  EL +ER  VKQLGL+
Sbjct: 301 IDDFSRARIDASVKELVEERDTVKQLGLV 329


>tr|C6WLQ8|C6WLQ8_ACTMD Tax_Id=446462 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Actinosynnema mirum]
          Length = 329

 Score =  414 bits (1064), Expect = e-114
 Identities = 212/325 (65%), Positives = 247/325 (76%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P+ LRLLEI  A+KA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGHLLGPDVPVRLRLLEIPQAVKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G++I  D  K FDGVN+ALLVGARPR  GMERGDLL+ANG IF  QG+A+NA AA D
Sbjct: 65  LLDGIDITDDATKAFDGVNVALLVGARPRTKGMERGDLLQANGGIFKPQGEAINAGAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +RV V GNPANTNALIA  +APD+P ERF+A+TRLDHNRA++QLA K G +V DI+K+TI
Sbjct: 125 VRVLVVGNPANTNALIAQQHAPDVPAERFTAMTRLDHNRALSQLAKKLGVSVDDIKKLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+F+AE+ GKNAAE V DQAW+E+ FIPTVAK                  
Sbjct: 185 WGNHSATQYPDLFNAEVAGKNAAEAVNDQAWLENDFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT EG+WVSMA+ SDGSYGVPEGLISSFPVT  DG ++IV+GL I++F
Sbjct: 245 NAALNHIHDWVNGTAEGDWVSMAIPSDGSYGVPEGLISSFPVTVKDGKYSIVQGLEINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S AEL +ER AVK LGLI
Sbjct: 305 SRARIDASVAELVEERDAVKALGLI 329


>sp|B1W3N4|MDH_STRGG Tax_Id=455632 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Streptomyces griseus subsp.
           griseus]
          Length = 329

 Score =  411 bits (1057), Expect = e-113
 Identities = 211/325 (64%), Positives = 241/325 (74%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P+ LRLLEI   LKA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGHLLGPDVPVNLRLLEIPQGLKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G+EI  DPN  F G N+ALLVGARPR  GMERGDLL ANG IF  QGKA+N  AA D
Sbjct: 65  LLRGIEITDDPNVGFAGANVALLVGARPRTKGMERGDLLAANGGIFKPQGKAINDHAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           I+V V GNPANTNALIA   APD+P ERF+A+TRLDHNRAI+QLA KTG+AV+DI+K+TI
Sbjct: 125 IKVLVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRAISQLAAKTGAAVSDIKKLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHAEI GKNAAE V D+ W+ D FIPTVAK                  
Sbjct: 185 WGNHSATQYPDIFHAEIAGKNAAETVNDEVWLADTFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT EG+W SM + SDGSYGVPEG+ISSFPVTT DG + IV+GL I++F
Sbjct: 245 NAAIDHVHTWVNGTAEGDWTSMGIPSDGSYGVPEGIISSFPVTTKDGKYEIVQGLDINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  EL +ER AV++LGLI
Sbjct: 305 SRTRIDASVKELTEERDAVRELGLI 329


>sp|Q82HS2|MDH_STRAW Tax_Id=33903 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Streptomyces avermitilis]
          Length = 329

 Score =  410 bits (1055), Expect = e-113
 Identities = 206/325 (63%), Positives = 240/325 (73%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P++LRLLEI PALKA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGQLLGADVPVKLRLLEITPALKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G++I  DPN  FDG N+ LLVGARPR  GMERGDLL ANG IF  QGKA+N  AA D
Sbjct: 65  LLQGIDITDDPNVAFDGTNVGLLVGARPRTKGMERGDLLSANGGIFKPQGKAINDNAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +++ V GNPANTNALIA   APD+P ERF+A+TRLDHNRA+ QLA KTGS V DI+++TI
Sbjct: 125 VKILVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRALTQLAKKTGSTVADIKRLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHA + GKNAAEVV D+ W+ + FIPTVAK                  
Sbjct: 185 WGNHSATQYPDIFHASVAGKNAAEVVNDEKWLAEDFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT +G+W SM + SDGSYGVPEGLISSFPVTT DG + IV+GL I++F
Sbjct: 245 NAAIDHVYTWVNGTADGDWTSMGIPSDGSYGVPEGLISSFPVTTKDGRYEIVQGLEINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  EL +ER AV+ LGLI
Sbjct: 305 SRARIDASVKELEEEREAVRALGLI 329


>tr|C8XK71|C8XK71_NAKMY Tax_Id=479431 SubName: Full=Malate
           dehydrogenase;[Nakamurella multipartita]
          Length = 328

 Score =  410 bits (1055), Expect = e-113
 Identities = 210/329 (63%), Positives = 241/329 (73%), Gaps = 1/329 (0%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+ V VTGAAGQIGY+LLFR+ASG +LG D P+ L LLEI PALKA EG  MELDD
Sbjct: 1   MSKAPVTVTVTGAAGQIGYALLFRIASGVMLGPDTPVVLNLLEITPALKAAEGTAMELDD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LLAG+ I  DP K FDG N+ LLVGARPRGPGMER DLLEANG IF  QG A+N V
Sbjct: 61  CAFPLLAGINITDDPRKAFDGANIGLLVGARPRGPGMERADLLEANGGIFKPQGAAINDV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DIRV V GNPANTNALIA ++APD+P ERF+A+ RLDHNRA  Q+A K G  V+++ 
Sbjct: 121 AADDIRVLVVGNPANTNALIAQSHAPDVPAERFTAMMRLDHNRAKTQVAQKLGVPVSEVT 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           KMTIWGNHSA+QYPD+FHAE+GGK  AE V DQAW+ D FIPTVAK              
Sbjct: 181 KMTIWGNHSASQYPDLFHAEVGGKPVAEQV-DQAWLADTFIPTVAKRGAAIIDARGASSA 239

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        W+LGTP G+WVS AVVSDGSYG+PEGLI+  P T+T G W +V+GL 
Sbjct: 240 ASAANAAIDHINSWVLGTPAGDWVSSAVVSDGSYGIPEGLIAGVPATSTGGAWQVVQGLE 299

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           IDDFSR +ID S  ELADER AV+ LGLI
Sbjct: 300 IDDFSRAKIDASVKELADERDAVRSLGLI 328


>tr|B5HVE5|B5HVE5_9ACTO Tax_Id=463191 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Streptomyces sviceus ATCC
           29083]
          Length = 329

 Score =  409 bits (1052), Expect = e-112
 Identities = 205/325 (63%), Positives = 241/325 (74%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P++LRLLEI PALKA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGQLLGADVPVKLRLLEITPALKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G++I  DPN  FDG N+ LLVGARPR  GMERGDLLEANG IF  QGKA+N  AA D
Sbjct: 65  LLQGIDITDDPNVAFDGTNVGLLVGARPRTKGMERGDLLEANGGIFKPQGKAINDHAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +++ V GNPANTNALIA   APD+P ERF+A+TRLDHNRA+ QLA KTG++V DI+++TI
Sbjct: 125 VKILVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRALTQLAKKTGTSVADIKRLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHA + GKNAAE V D+ W+ + FIPTVAK                  
Sbjct: 185 WGNHSATQYPDIFHATVAGKNAAETVNDEKWLAEDFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT +G+W SM + SDGSYGVPEGLISSFPVTT DG + IV+GL I++F
Sbjct: 245 NAAIDHVYTWVNGTADGDWASMGIPSDGSYGVPEGLISSFPVTTKDGVYEIVQGLEINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  EL +ER AV+ LGLI
Sbjct: 305 SRARIDASVKELEEEREAVRALGLI 329


>sp|B2GKC8|MDH_KOCRD Tax_Id=378753 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Kocuria rhizophila]
          Length = 328

 Score =  408 bits (1048), Expect = e-112
 Identities = 210/329 (63%), Positives = 246/329 (74%), Gaps = 1/329 (0%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+ VAVTGAAGQIGYSLLFR+A G +LG  RP+ LRLLEI  AL ALEG VMEL D
Sbjct: 1   MSLTPVTVAVTGAAGQIGYSLLFRIAHGDMLGRQRPVRLRLLEIPSALPALEGTVMELQD 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LLA VEIG+DP +VFDG  LALLVGARPR  GMERGDLLEANGAIFT QG+ALN V
Sbjct: 61  CAFPLLADVEIGSDPREVFDGAQLALLVGARPRTKGMERGDLLEANGAIFTEQGRALNDV 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           A  D+RV VTGNPANTNALIA  NAPDIP  RFSALTRLDHNRA+A LA +TG++V D++
Sbjct: 121 ADHDVRVVVTGNPANTNALIAQRNAPDIPASRFSALTRLDHNRAVAMLAAQTGASVDDVK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
            +++WGNHSATQYPD+ HA + G+ A ++V  + W++D FIPTVAK              
Sbjct: 181 HLSVWGNHSATQYPDLDHARVAGRPALDLV-SREWVQDTFIPTVAKRGAAILEARGASSA 239

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                         +LG   G+W SM+VVSDGSYGVPEGL+SSFPVTT+ GDW+IV+GL 
Sbjct: 240 ASAANATIDHARDLMLGNHRGDWTSMSVVSDGSYGVPEGLVSSFPVTTSGGDWSIVQGLD 299

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           I +FSR RID S AEL  ER AV++LGLI
Sbjct: 300 ISEFSRARIDASVAELESERAAVQELGLI 328


>tr|C9YTG2|C9YTG2_STRSW Tax_Id=680198 (mdh)SubName: Full=Malate
           dehydrogenase;[Streptomyces scabies]
          Length = 329

 Score =  407 bits (1047), Expect = e-112
 Identities = 207/325 (63%), Positives = 241/325 (74%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P++LRLLEI PALKA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGQLLGADVPVKLRLLEITPALKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G++I  DPN  FDG N+ LLVGARPR  GMERGDLLEANG IF  QGKA+N  AA D
Sbjct: 65  LLQGIDITDDPNVAFDGANVGLLVGARPRTKGMERGDLLEANGGIFKPQGKAINDNAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           I+V V GNPANTNALIA   APD+P ERF+A+TRLDHNRA+ QL+ KTG  V++I+++TI
Sbjct: 125 IKVLVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRALTQLSKKTGVPVSEIQRLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHA + GKNAAEVVGD+ W+ + FIPTVAK                  
Sbjct: 185 WGNHSATQYPDIFHATVAGKNAAEVVGDEKWLAEDFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT EG+W SM + SDGSYGV EGLISSFPVT  DG + IV+GL I++F
Sbjct: 245 NAAIDHVHTWVNGTAEGDWASMGIPSDGSYGVAEGLISSFPVTVKDGTYEIVQGLEINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  ELA+ER AV+ LGLI
Sbjct: 305 SRTRIDASVQELAEEREAVRALGLI 329


>sp|Q47TT4|MDH_THEFY Tax_Id=269800 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Thermobifida fusca]
          Length = 330

 Score =  406 bits (1044), Expect = e-111
 Identities = 204/325 (62%), Positives = 242/325 (74%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG+D P+ LRLLEI  A+KA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGQLLGVDTPVRLRLLEIPQAIKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LLAGV+I  DP K FDGVN+ALLVGARPR  GMER DLLEANG IF  QG A+N  AA D
Sbjct: 65  LLAGVDIYDDPRKAFDGVNVALLVGARPRTKGMERRDLLEANGGIFGPQGAAINDGAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +RV V GNPANTNALIA  +APDIP +RF+A+TRLDHNRA++QLA K   +V+DI+K+TI
Sbjct: 125 VRVLVVGNPANTNALIAQAHAPDIPADRFTAMTRLDHNRALSQLAAKLNVSVSDIKKLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHAE+ G++A E V D+ W+ D FIPTVAK                  
Sbjct: 185 WGNHSATQYPDIFHAEVNGRSAVEAVNDEEWLRDTFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GTPEG+W S+A+ SDGSYGVPEGL+SSFPV + +G W IV+GL I++F
Sbjct: 245 NAAIDHVYDWVNGTPEGDWTSVALPSDGSYGVPEGLVSSFPVVSRNGSWEIVQGLEINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  EL +ER AV+ LGLI
Sbjct: 305 SRERIDASVRELEEEREAVRALGLI 329


>tr|C9N8P8|C9N8P8_9ACTO Tax_Id=591167 SubName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Streptomyces flavogriseus
           ATCC 33331]
          Length = 329

 Score =  406 bits (1044), Expect = e-111
 Identities = 208/325 (64%), Positives = 241/325 (74%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P+ LRLLEI   LKA EG  MELDDCAF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGHLLGPDVPVNLRLLEIPQGLKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL  +EI  +P+  F G N+ALLVGARPR  GMERGDLL ANG IF  QGKA+N  AA D
Sbjct: 65  LLRNIEITDNPDVGFAGANVALLVGARPRTKGMERGDLLSANGGIFKPQGKAINDNAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           I+V V GNPANTNALIA   APD+P ERF+A+TRLDHNRAI+QLA KTG+AV+DI+++TI
Sbjct: 125 IKVLVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRAISQLAAKTGAAVSDIKRLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHAEI GKNAAEVV D+ W+ D FIPTVAK                  
Sbjct: 185 WGNHSATQYPDIFHAEIAGKNAAEVVNDEVWLADTFIPTVAKRGAAIIEARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT EG+W SM + SDGSYGVPEG+ISSFPVTT DG + IV+GL I++F
Sbjct: 245 NAAIDHVHTWVNGTAEGDWTSMGIPSDGSYGVPEGIISSFPVTTKDGKYEIVQGLDINEF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  EL +ER AV++LGLI
Sbjct: 305 SRARIDASVQELIEERDAVRELGLI 329


>tr|C7MV61|C7MV61_SACVD Tax_Id=471857 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Saccharomonospora viridis]
          Length = 329

 Score =  405 bits (1042), Expect = e-111
 Identities = 208/325 (64%), Positives = 245/325 (75%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D+P+ LRLLEI  A+KA EG  +EL+D AF 
Sbjct: 5   PVNVTVTGAAGQIGYALLFRIASGQLLGQDKPVRLRLLEIPQAVKAAEGTALELEDGAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LLAG++I  +P   FDG N+ALLVGARPR  GMERGDLLEANG IF  QG+ALNA AA D
Sbjct: 65  LLAGIDIYDNPKDAFDGANIALLVGARPRTKGMERGDLLEANGGIFKPQGEALNAGAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           I+V V GNPANTNALIA  NAPDIP ERF+A+TRLDHNRAIAQLA K    V+D++KMTI
Sbjct: 125 IKVLVVGNPANTNALIAQANAPDIPAERFTAMTRLDHNRAIAQLAKKLQVPVSDVKKMTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+F+AE+ G+NAA+ V DQ W+E+ FIP VAK                  
Sbjct: 185 WGNHSATQYPDIFNAEVKGENAAQAVNDQQWLENEFIPRVAKRGAEIIEVRGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GTP+G+WVSMAV SDGSYGVPEGLISSFPV   +G + IV+GL I+DF
Sbjct: 245 SAAIDHIYDWVNGTPDGDWVSMAVPSDGSYGVPEGLISSFPVVCKNGSYEIVQGLQINDF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S AEL++ER AV++LGLI
Sbjct: 305 SRARIDASVAELSEEREAVRKLGLI 329


>sp|A4FFX3|MDH_SACEN Tax_Id=405948 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Saccharopolyspora erythraea]
          Length = 328

 Score =  404 bits (1037), Expect = e-110
 Identities = 208/325 (64%), Positives = 241/325 (74%), Gaps = 1/325 (0%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG L+G D P+ LRLLEI  A+KA EG  MELDDCAF 
Sbjct: 5   PVTVTVTGAAGQIGYALLFRIASGQLIGPDTPVRLRLLEIPQAVKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G+E+  D    FDG N+ALLVGARPR  GMERGDLLEANG IF  QG+A+NA AA D
Sbjct: 65  LLQGIEVTDDARTAFDGTNVALLVGARPRTKGMERGDLLEANGGIFKPQGEAINAGAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +RV V GNPANTNALIA  +APD+P ERF+A+TRLDHNRA+ QLA K G +V DI+K+TI
Sbjct: 125 VRVLVVGNPANTNALIAQAHAPDVPAERFTAMTRLDHNRALTQLAQKLGVSVNDIKKLTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHAE+ GK AAE V DQAW+ D FIPTVAK                  
Sbjct: 185 WGNHSATQYPDLFHAEVNGKVAAEQV-DQAWLADTFIPTVAKRGAAIIEARGASSAASAA 243

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GTPEG+W S AVVSDGSYGVPEGLISSFPV   DG + IV+GL ID+F
Sbjct: 244 NAAIDHIHTWVNGTPEGDWTSAAVVSDGSYGVPEGLISSFPVVARDGRYEIVQGLEIDEF 303

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  EL++ER AV++LGL+
Sbjct: 304 SRQRIDASVNELSEERDAVRKLGLL 328


>tr|C5BZS1|C5BZS1_BEUC1 Tax_Id=471853 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Beutenbergia cavernae]
          Length = 328

 Score =  400 bits (1029), Expect = e-110
 Identities = 205/325 (63%), Positives = 239/325 (73%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQIGY+LLFR+ASG LLG D P+ LRLLEI PA++A EGV +EL+DCAF 
Sbjct: 4   PVTVTVTGAAGQIGYALLFRIASGQLLGPDTPVRLRLLEITPAVQAAEGVALELEDCAFP 63

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LLAG +I  D    FDG N+ALLVGARPR  GMERGDLLEANG IF  QGKA+N  AA D
Sbjct: 64  LLAGTDITDDVAAAFDGTNVALLVGARPRTAGMERGDLLEANGGIFGPQGKAINDGAADD 123

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +RV V GNPANTNA IA ++APD+P +RF+A+TRLDHNRA++QLATKTG+AV+DI ++ I
Sbjct: 124 VRVLVVGNPANTNAYIAKSHAPDVPADRFTAMTRLDHNRALSQLATKTGAAVSDIARLAI 183

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+ HA I G+ A EVV D AW+ D FIPTVAK                  
Sbjct: 184 WGNHSATQYPDLTHATIAGRPALEVVSDDAWVADDFIPTVAKRGAAIIAARGASSAASAA 243

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W  GTPEG+W S  VVSDGSYGVPEGLISSFPVT++ G W IV+GL +D F
Sbjct: 244 NAAIDHVHTWTHGTPEGDWTSAGVVSDGSYGVPEGLISSFPVTSSGGAWQIVQGLEVDAF 303

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S AEL +ER AV  LGL+
Sbjct: 304 SRERIDASVAELVEERDAVASLGLV 328


>tr|C1RNE1|C1RNE1_9CELL Tax_Id=446466 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Cellulomonas flavigena DSM
           20109]
          Length = 330

 Score =  399 bits (1025), Expect = e-109
 Identities = 204/325 (62%), Positives = 236/325 (72%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P  V VTGAAGQIGY+L FR+ASG LLG D P+ LR+LEI PA+KA EGV MELDDCAF 
Sbjct: 6   PAVVTVTGAAGQIGYALAFRIASGQLLGPDTPVRLRMLEIPPAVKAAEGVAMELDDCAFP 65

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL G++I  D    FDGVN+ALLVGARPR  GMERGDLL ANG IF  QG A+NA AA D
Sbjct: 66  LLDGIDITDDATAAFDGVNVALLVGARPRTKGMERGDLLSANGGIFGPQGAAINAGAADD 125

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           +RV V GNPANTNA IA  +APD+P +RF+A+TRLDHNRA+AQL  +TG+A+ DI ++ I
Sbjct: 126 VRVLVVGNPANTNAYIASAHAPDVPADRFTAMTRLDHNRALAQLRHRTGAAIDDIARLAI 185

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+ HA IGG+ A EVVGD AW+ D FIPTVAK                  
Sbjct: 186 WGNHSATQYPDLTHATIGGRPALEVVGDDAWVRDGFIPTVAKRGAAIIEARGASSAASAA 245

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GTPEG+W S  VVSDGSYGVPEGLISSFPVT + G +TIV GL +D F
Sbjct: 246 NAAIDHVHTWVHGTPEGDWTSAGVVSDGSYGVPEGLISSFPVTASGGAYTIVPGLEVDGF 305

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S AEL +ER AV+ LGL+
Sbjct: 306 SRERIDASVAELVEEREAVRALGLV 330


>sp|Q2J7E7|MDH_FRASC Tax_Id=106370 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Frankia sp.]
          Length = 329

 Score =  398 bits (1022), Expect = e-109
 Identities = 203/329 (61%), Positives = 242/329 (73%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+ V VTGAAGQIGY+LLFR+ASG LLG D P++LRLLEI  A++A EG  +EL+D
Sbjct: 1   MSSTPVNVTVTGAAGQIGYALLFRIASGQLLGADTPVKLRLLEIPQAVRAAEGTALELED 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
            AF LLAGV++  D  + F+G N+ALLVGARPR  GMERGDLL ANG IF  QG+A+N+ 
Sbjct: 61  SAFPLLAGVDVFDDAKRAFEGTNVALLVGARPRTKGMERGDLLSANGGIFKPQGEAINSG 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DIRV V GNPANTNALIA T+APD+P ERF+A+TRLDHNRAIAQLA K G    +I+
Sbjct: 121 AAEDIRVLVVGNPANTNALIAQTHAPDVPAERFTAMTRLDHNRAIAQLAKKLGVPSAEIK 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           K+TIWGNHSATQYPD+FHAE+GG++ AE VGDQAWI D FIP VAK              
Sbjct: 181 KITIWGNHSATQYPDIFHAEVGGRSGAEAVGDQAWIADEFIPRVAKRGAEIIEVRGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        W+ GTP G+W S A+ SDGSYGVPEGLISSFPVT + G + IV+GL 
Sbjct: 241 ASAASAAIDHIFTWVNGTPAGDWTSAAIPSDGSYGVPEGLISSFPVTASGGRFEIVQGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           +D FSR +ID S  ELA+ER AV+ LGLI
Sbjct: 301 LDAFSREKIDASVRELAEEREAVRALGLI 329


>sp|Q0RE66|MDH_FRAAA Tax_Id=326424 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Frankia alni]
          Length = 329

 Score =  396 bits (1018), Expect = e-108
 Identities = 202/329 (61%), Positives = 240/329 (72%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+ V VTGAAGQIGY+LLFR+ASG LLG D P+ LRLLEI  A++A EG  +EL+D
Sbjct: 1   MSSTPVNVTVTGAAGQIGYALLFRIASGQLLGADTPVRLRLLEIPQAVRAAEGTALELED 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
            AF LLAGV++  D  + F+G N+ALLVGARPR  GMERGDLL ANG IF  QG+A+N+ 
Sbjct: 61  SAFPLLAGVDVFDDAKRAFEGTNVALLVGARPRTKGMERGDLLSANGGIFKPQGEAINSG 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA DIRV V GNPANTNALIA T+APD+P ERF+A+TRLDHNRAIAQLA K G    +IR
Sbjct: 121 AAEDIRVLVVGNPANTNALIAQTHAPDVPAERFTAMTRLDHNRAIAQLAKKLGVPSAEIR 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           K+TIWGNHSATQYPD+FHA++GG++ AE VGDQ WI + FIP VAK              
Sbjct: 181 KITIWGNHSATQYPDIFHAQVGGRSGAEAVGDQKWIAEEFIPRVAKRGAEIIEVRGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        W+ GTPEG+W S A+ SDGSYGVPEGLISSFPVT   G + IV+GL 
Sbjct: 241 ASAASAAIDHVYTWVNGTPEGDWTSAAIPSDGSYGVPEGLISSFPVTAAGGKFEIVQGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           +D FSR +ID S  ELA+ER AV+ LGLI
Sbjct: 301 LDAFSREKIDASVRELAEEREAVRALGLI 329


>tr|C4EH55|C4EH55_STRRS Tax_Id=479432 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Streptosporangium roseum DSM
           43021]
          Length = 325

 Score =  391 bits (1005), Expect = e-107
 Identities = 204/325 (62%), Positives = 238/325 (73%), Gaps = 4/325 (1%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+KV VTGAAGQIGY+LLFR+ASG LLG D P++L LLEI  A+KA EG  MELDDCAF 
Sbjct: 5   PVKVTVTGAAGQIGYALLFRIASGQLLGADVPVKLSLLEIPQAVKAAEGTAMELDDCAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL+G+E+  D NK FDG ++ALLVGARPR  GMERGDLL+ANG IF  QGKA+N  AA D
Sbjct: 65  LLSGIEVTDDANKAFDGASVALLVGARPRTAGMERGDLLQANGGIFGPQGKAINDNAADD 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           IRV V GNPANTN+LIA  +APD+P ERF+A+TRLDHNRA++QLA K    V +I+KMTI
Sbjct: 125 IRVLVVGNPANTNSLIAQQHAPDVPAERFTAMTRLDHNRALSQLAAKLQVPVAEIKKMTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+FHAE+GGK AAE V D+AW+ D FIPTVAK                  
Sbjct: 185 WGNHSATQYPDLFHAEVGGKIAAEQV-DEAWLRDTFIPTVAKRGAAIIEARGASSAASAA 243

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+ GT    W S A+ SDGSYGVPEGLISSFPV + DG W I++GL ID F
Sbjct: 244 NAAIDHVFDWVNGT---EWTSAAIPSDGSYGVPEGLISSFPVASRDGKWEIIQGLEIDAF 300

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR RID S  EL +ER AV++LGLI
Sbjct: 301 SRERIDASVRELEEERAAVRELGLI 325


>tr|C9K9P2|C9K9P2_9MICO Tax_Id=446469 SubName: Full=Malate
           dehydrogenase (NAD); EC=1.1.1.37;[Sanguibacter keddieii
           DSM 10542]
          Length = 329

 Score =  388 bits (996), Expect = e-106
 Identities = 195/329 (59%), Positives = 234/329 (71%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +SP P+ V VTGAAGQIGY+LLFR+ASG LLG D P+ LRLLEI   +KA EG  MEL+D
Sbjct: 1   MSPTPVNVTVTGAAGQIGYALLFRIASGQLLGPDVPVRLRLLEIPQGVKAAEGTAMELED 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
           CAF LLAG++I  +P   F G N+ LLVGARPR  GMERGDLLEANG IF  QG A+NA 
Sbjct: 61  CAFPLLAGIDIFDNPTDGFAGTNIGLLVGARPRTKGMERGDLLEANGGIFGPQGAAINAG 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA D+R+ V GNPANTNALIA ++APD+P +RF+A+TRLDHNRA++Q ATK G  V+ +R
Sbjct: 121 AADDVRILVVGNPANTNALIAASHAPDVPSDRFTAMTRLDHNRALSQAATKAGVPVSQVR 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           ++TIWGNHSATQYPD+FHAEI G  A  +  D  W+ D FIPTVA               
Sbjct: 181 RLTIWGNHSATQYPDLFHAEIDGAPATALTDDSTWLTDDFIPTVATRGAAIIEARGASSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        W+ GTP+G+W S  +VSDGSYGVPEGL+SSFPV + DG W IV+GL 
Sbjct: 241 ASAANAAVDHVRDWVHGTPKGDWTSAGIVSDGSYGVPEGLVSSFPVVSRDGRWEIVQGLE 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           + DFSR RID S  EL +ER AV+ LGLI
Sbjct: 301 VGDFSRERIDASVKELVEERDAVRSLGLI 329


>sp|C1B155|MDH_RHOOB Tax_Id=632772 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Rhodococcus opacus]
          Length = 331

 Score =  387 bits (993), Expect = e-105
 Identities = 192/328 (58%), Positives = 234/328 (71%)

Query: 2   SPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDC 61
           SP P  V VTGAAG IGY+ LFR+A+G++LG D PI LRLLEI PA+ A EG  MELDD 
Sbjct: 4   SPTPAVVTVTGAAGSIGYAALFRIAAGAMLGPDTPIRLRLLEIPPAVSAAEGTAMELDDS 63

Query: 62  AFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVA 121
           AF LL  VE+  DP + FDG ++ALL+G+RPR  GMERGDLL ANG IFT QG+A+N VA
Sbjct: 64  AFPLLLDVEVHDDPKRGFDGTDVALLIGSRPRSKGMERGDLLAANGQIFTVQGRAINQVA 123

Query: 122 AADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRK 181
           A  +RV V GNPANTNAL+A  NAPD+P ERF+ALTRLDHNRAIAQLA  +G+AV DI +
Sbjct: 124 ADGVRVLVVGNPANTNALVAANNAPDVPAERFTALTRLDHNRAIAQLARHSGAAVRDISR 183

Query: 182 MTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXX 241
           +TIWGNHS+TQYPD+FHA +G ++ A++  D+ W+   FIPTVA                
Sbjct: 184 VTIWGNHSSTQYPDIFHARVGDRSGADIAADREWLTGDFIPTVANRGSAIIEARGTSSAA 243

Query: 242 XXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGI 301
                       W+LGTPEG+W S+A+ S G+YGVPEGL+SSFPV + DG W +V GL I
Sbjct: 244 SAANAAIDHVHDWVLGTPEGDWTSVALPSTGAYGVPEGLVSSFPVRSVDGAWQVVEGLEI 303

Query: 302 DDFSRGRIDKSTAELADERMAVKQLGLI 329
           DDFSR RID S A+L  ER AV+ +G I
Sbjct: 304 DDFSRKRIDASVADLESERDAVRGMGFI 331


>tr|C1XYV8|C1XYV8_9DEIN Tax_Id=526227 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Meiothermus silvanus DSM
           9946]
          Length = 329

 Score =  383 bits (983), Expect = e-104
 Identities = 198/325 (60%), Positives = 235/325 (72%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P++VAVTGAAGQIGYSLLFR+A+G +LG D+P+ L+LLEI PALKAL+GVVMEL+DCAF 
Sbjct: 4   PVRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVILQLLEITPALKALQGVVMELEDCAFP 63

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
            LAGV    DPN  F   + ALLVGA PR  GMER DLL+ANGAIFTAQGKAL+  A   
Sbjct: 64  TLAGVVQTDDPNIAFADADYALLVGAMPRKAGMERADLLQANGAIFTAQGKALSENAKKS 123

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           ++V V GNPANTNALIA  NAP +   +F A+TRLDHNRAI+QLA +    VT I+KMTI
Sbjct: 124 VKVLVVGNPANTNALIAYHNAPGLSPRQFHAMTRLDHNRAISQLAARVKKPVTSIKKMTI 183

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHS TQYPD+FH E+ G+NA E+VGD  W  + +IPTVAK                  
Sbjct: 184 WGNHSLTQYPDLFHCEVDGQNAYELVGDPEWYANTYIPTVAKRGAAIIEARGASSAASAA 243

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W LGTPEG+WVSMA+ SDGSYG+PEGL+ S+P     GD+TIV+GL I+DF
Sbjct: 244 SAAIDHMRDWALGTPEGDWVSMAIPSDGSYGIPEGLVYSYPCVCKGGDFTIVQGLEINDF 303

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR ++D S  ELADER AVKQLGLI
Sbjct: 304 SRQKMDASAKELADERDAVKQLGLI 328


>sp|Q0S365|MDH_RHOSR Tax_Id=101510 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Rhodococcus sp.]
          Length = 331

 Score =  377 bits (967), Expect = e-102
 Identities = 191/328 (58%), Positives = 228/328 (69%)

Query: 2   SPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDC 61
           SP P  V VTGAAG IGY+ LFR+A+G +LG D PI LRLLEI  A+ A EG  MELDD 
Sbjct: 4   SPPPAVVTVTGAAGSIGYASLFRIAAGEMLGPDTPIRLRLLEIPSAVSAAEGTAMELDDS 63

Query: 62  AFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVA 121
           AF LL  +E+  DP + FDG ++ALL+G+RPR  GMERGDLL ANG IFT QG+ALN VA
Sbjct: 64  AFPLLRDIEVHDDPKRGFDGTDVALLIGSRPRSKGMERGDLLAANGQIFTVQGRALNQVA 123

Query: 122 AADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRK 181
           A  +RV V GNPANTNAL+A  NAPDIP ERF+ALTRLDHNRAIAQLA  +G+AV DIR+
Sbjct: 124 ADGVRVLVVGNPANTNALVAANNAPDIPAERFTALTRLDHNRAIAQLARHSGAAVKDIRR 183

Query: 182 MTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXX 241
           + IWGNHS+TQYPD+FHA +G ++ AE   D+ W+   FIPTVA                
Sbjct: 184 VAIWGNHSSTQYPDIFHARVGDRSGAEFAADREWLTGDFIPTVANRGSAIIEARGASSAA 243

Query: 242 XXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGI 301
                       W+LGTP+ +W S+A+ S G+YGVPEGL+SSFPV + DG W IV GL I
Sbjct: 244 SAANAAIDHVHDWVLGTPDDDWTSVALPSTGAYGVPEGLVSSFPVRSVDGSWQIVDGLEI 303

Query: 302 DDFSRGRIDKSTAELADERMAVKQLGLI 329
           DDFSR  ID S  EL  ER AV+ +G I
Sbjct: 304 DDFSRKLIDASVGELESERDAVRGMGFI 331


>tr|C0ZZ60|C0ZZ60_RHOE4 Tax_Id=234621 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Rhodococcus erythropolis]
          Length = 329

 Score =  374 bits (961), Expect = e-102
 Identities = 190/329 (57%), Positives = 233/329 (70%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+ V VTGA+GQI Y +LFR+A+G +LG D PI+LRLLEI  A+ A EGV MEL+D
Sbjct: 1   MSIAPVTVTVTGASGQIAYGMLFRIAAGEMLGADVPIKLRLLEIPAAVSAAEGVAMELED 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
            AF LL+ ++I  DP+  F G N+ +LVGARPR  GMER DLL ANGAIFTA GKA+N  
Sbjct: 61  GAFPLLSSIDITDDPDVAFSGANVGMLVGARPRSKGMERADLLSANGAIFTAHGKAINNN 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA+D++V V GNPANTNALIAM NAPD+P  RFSALTRLDHNRAIAQ+  KTG   + +R
Sbjct: 121 AASDVKVLVVGNPANTNALIAMNNAPDVPDTRFSALTRLDHNRAIAQVVKKTGVRASSVR 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           K+++WGNHSATQYPD+ HA + G+ A  V+ D+ W+E+ FIPTV                
Sbjct: 181 KVSVWGNHSATQYPDLSHATVAGEPALAVINDRDWVENDFIPTVQVRGTAIIAARGSSSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        W++GT E +WVSMAV SDGSYGVPEGLISSFPVT  DG++ IV  L 
Sbjct: 241 ASAASASIDHVRDWVIGTAEDDWVSMAVCSDGSYGVPEGLISSFPVTCADGEFAIVPDLA 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           IDDFSR RID S +EL  ER AV++LG +
Sbjct: 301 IDDFSRERIDLSVSELEQERAAVRELGFV 329


>tr|C3JNL4|C3JNL4_RHOER Tax_Id=596309 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Rhodococcus erythropolis
           SK121]
          Length = 329

 Score =  374 bits (960), Expect = e-102
 Identities = 190/329 (57%), Positives = 233/329 (70%)

Query: 1   VSPRPLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDD 60
           +S  P+ V VTGA+GQI Y +LFR+A+G +LG D PI+LRLLEI  A+ A EGV MEL+D
Sbjct: 1   MSIAPVTVTVTGASGQIAYGMLFRIAAGEMLGADVPIKLRLLEIPAAVSAAEGVAMELED 60

Query: 61  CAFLLLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAV 120
            AF LL+ ++I  DP+  F G N+ +LVGARPR  GMER DLL ANGAIFTA GKA+N  
Sbjct: 61  GAFPLLSSIDITDDPDVAFSGANVGMLVGARPRSKGMERADLLSANGAIFTAHGKAINNN 120

Query: 121 AAADIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIR 180
           AA+D++V V GNPANTNALIAM NAPD+P  RFSALTRLDHNRAIAQ+  KTG   + +R
Sbjct: 121 AASDVKVLVVGNPANTNALIAMNNAPDVPDARFSALTRLDHNRAIAQVVKKTGVRASSVR 180

Query: 181 KMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXX 240
           K+++WGNHSATQYPD+ HA + G+ A  V+ D+ W+E+ FIPTV                
Sbjct: 181 KVSVWGNHSATQYPDLSHATVAGEPALAVIDDRDWVENDFIPTVQVRGTAIIAARGSSSA 240

Query: 241 XXXXXXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLG 300
                        W++GT E +WVSMAV SDGSYGVPEGLISSFPVT  DG++ IV  L 
Sbjct: 241 ASAASASIDHVRDWVIGTAEDDWVSMAVCSDGSYGVPEGLISSFPVTCADGEFAIVPDLA 300

Query: 301 IDDFSRGRIDKSTAELADERMAVKQLGLI 329
           IDDFSR RID S +EL  ER AV++LG +
Sbjct: 301 IDDFSRERIDLSVSELEQERAAVRELGFV 329


>tr|C1XNQ5|C1XNQ5_MEIRU Tax_Id=504728 RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Meiothermus ruber DSM 1279]
          Length = 329

 Score =  371 bits (952), Expect = e-101
 Identities = 189/325 (58%), Positives = 232/325 (71%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P++VAVTGAAGQIGYSLLFR+A+G +LG D+P+ L+LLEI PALKAL GV+MEL+DCAF 
Sbjct: 4   PVRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVILQLLEITPALKALGGVIMELEDCAFP 63

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
            LAG+    DPN  F   + ALLVGA PR  GMER DLL+ANGAIFTAQG+AL+  A   
Sbjct: 64  TLAGIVATDDPNIAFGDADYALLVGAMPRKQGMERADLLQANGAIFTAQGRALSENARKH 123

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           ++V V GNPANTNALI   NAP++   +  A+TRLDHNRAI+QLA +    V++I+KMTI
Sbjct: 124 VKVLVVGNPANTNALITYKNAPNLSPRQIHAMTRLDHNRAISQLAARLKVPVSEIKKMTI 183

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHS TQYPD+FH E+GG+NA E+VGD  W  + +IP VAK                  
Sbjct: 184 WGNHSLTQYPDLFHCEVGGRNAYELVGDHDWYANTYIPKVAKRGAEIIEARGASSAASAA 243

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W LGTP G+WVSMA+ SDGSYG+PEGL+ S+P    DGD+ IV+GL I++F
Sbjct: 244 SAAIDHMRDWALGTPAGDWVSMAIPSDGSYGIPEGLVYSYPCVCKDGDFEIVQGLEINEF 303

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR ++D S  ELADER AV QLGLI
Sbjct: 304 SRSKMDASAKELADERDAVLQLGLI 328


>sp|Q5YTI1|MDH_NOCFA Tax_Id=37329 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Nocardia farcinica]
          Length = 334

 Score =  369 bits (946), Expect = e-100
 Identities = 193/323 (59%), Positives = 229/323 (70%), Gaps = 1/323 (0%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAGQI Y LLFR+ASG++LG   PI LRLLEI  A+ +LEGV MEL+D AF 
Sbjct: 9   PVTVTVTGAAGQIAYGLLFRIASGAMLGPHTPIRLRLLEIPAAVASLEGVAMELEDGAFP 68

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
           LL  ++I  DP   F G N+ALLVGARPR  GMER DLL ANG IFT QG+A+NAVAA D
Sbjct: 69  LLDAIDISDDPWTGFAGANVALLVGARPRTAGMERADLLAANGPIFTDQGQAINAVAADD 128

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           ++V V GNPANTNA IAM+NAPD+P ERF+A+TRLDHNRAIAQLA KTG+  T+I ++ +
Sbjct: 129 VKVLVVGNPANTNAFIAMSNAPDVPAERFTAMTRLDHNRAIAQLAKKTGAPATEIHRIAV 188

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHSATQYPD+ HA + G+ A E+V D+ W+ + FIPTV +                  
Sbjct: 189 WGNHSATQYPDLTHATVAGRPARELV-DEQWLREDFIPTVQQRGTAIIQARGASSAASAA 247

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W+LGTP G W SMAV SDGSYGVP+GLISSFPVT  DG + IV GL +D F
Sbjct: 248 SAAIDHIHDWVLGTPAGEWTSMAVPSDGSYGVPDGLISSFPVTCADGAYRIVEGLEVDAF 307

Query: 305 SRGRIDKSTAELADERMAVKQLG 327
           SR RID S AEL  ER AV +LG
Sbjct: 308 SRERIDASVAELTAEREAVVELG 330


>tr|C0W8W1|C0W8W1_9ACTO Tax_Id=525246 (mdh)RecName: Full=Malate
           dehydrogenase; EC=1.1.1.37;[Actinomyces urogenitalis DSM
           15434]
          Length = 329

 Score =  368 bits (945), Expect = e-100
 Identities = 185/325 (56%), Positives = 233/325 (71%)

Query: 5   PLKVAVTGAAGQIGYSLLFRLASGSLLGLDRPIELRLLEIEPALKALEGVVMELDDCAFL 64
           P+ V VTGAAG IGY+LLFR+ASG+LLG D+ + LRLLEI  A+KA EG  MEL D AF 
Sbjct: 5   PVNVTVTGAAGNIGYALLFRIASGALLGPDQRVNLRLLEIPQAVKAAEGTAMELFDSAFP 64

Query: 65  LLAGVEIGADPNKVFDGVNLALLVGARPRGPGMERGDLLEANGAIFTAQGKALNAVAAAD 124
            L  V+I  DP K F+G N+A LVG+ PR  GMER DLL ANG IF  QG+A+NA AA D
Sbjct: 65  TLGSVDIFDDPKKAFEGANIAFLVGSMPRKAGMERSDLLSANGGIFGPQGEAINAGAAED 124

Query: 125 IRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAIAQLATKTGSAVTDIRKMTI 184
           I+V V GNPANTNALIA ++APD+P  RF+A+TRLDHNRA+AQLA KTG+ V+D+ K+TI
Sbjct: 125 IKVLVVGNPANTNALIAASHAPDVPASRFTAMTRLDHNRALAQLAAKTGAHVSDLDKVTI 184

Query: 185 WGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIEDYFIPTVAKXXXXXXXXXXXXXXXXXX 244
           WGNHS+TQYPD+ HA + G+   E++ D+AW+E+ FIPTVAK                  
Sbjct: 185 WGNHSSTQYPDLTHATVKGQPVTELLADRAWVEEDFIPTVAKRGAAIIAARGASSAASAA 244

Query: 245 XXXXXXXXXWLLGTPEGNWVSMAVVSDGSYGVPEGLISSFPVTTTDGDWTIVRGLGIDDF 304
                    W LG  + +W S +V+SDGSYGVPEG+ISSFP  + +G+W IV+GL IDDF
Sbjct: 245 SAAIDHVRDWCLGVKDYSWTSASVMSDGSYGVPEGIISSFPAVSENGEWKIVQGLEIDDF 304

Query: 305 SRGRIDKSTAELADERMAVKQLGLI 329
           SR +ID S AEL +E+ AV+++GLI
Sbjct: 305 SRAKIDASAAELLEEKHAVQEMGLI 329


  Database: Amellifera_nr
    Posted date:  Jan 15, 2010  5:10 AM
  Number of letters in database: 3,808,957,724
  Number of sequences in database:  11,153,314
  
Lambda     K      H
   0.318    0.136    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11153314
Number of Hits to DB: 2,239,742,835
Number of extensions: 86925039
Number of successful extensions: 224536
Number of sequences better than 10.0: 4419
Number of HSP's gapped: 222611
Number of HSP's successfully gapped: 4470
Length of query: 329
Length of database: 3,808,957,724
Length adjustment: 137
Effective length of query: 192
Effective length of database: 2,280,953,706
Effective search space: 437943111552
Effective search space used: 437943111552
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 80 (35.4 bits)