BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ML1220
         (345 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,153,314 sequences; 3,808,957,724 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|P46715|BIOB_MYCLE Tax_Id=1769 (bioB)RecName: Full=Biotin synt...   686   0.0  
sp|B8ZR86|BIOB_MYCLB Tax_Id=561304 (bioB)RecName: Full=Biotin sy...   686   0.0  
tr|A4KHB4|A4KHB4_MYCTU Tax_Id=395095 SubName: Full=Biotin synthe...   605   e-171
sp|P0A506|BIOB_MYCTU Tax_Id=1773 (bioB)RecName: Full=Biotin synt...   604   e-171
sp|A5WMR0|BIOB_MYCTF Tax_Id=336982 (bioB)RecName: Full=Biotin sy...   604   e-171
sp|A5U2U5|BIOB_MYCTA Tax_Id=419947 (bioB)RecName: Full=Biotin sy...   604   e-171
sp|A1KJ05|BIOB_MYCBP Tax_Id=410289 (bioB)RecName: Full=Biotin sy...   604   e-171
sp|P0A507|BIOB_MYCBO Tax_Id=1765 (bioB)RecName: Full=Biotin synt...   604   e-171
tr|C6DSL9|C6DSL9_MYCTK Tax_Id=478434 SubName: Full=Biotin synthe...   604   e-171
tr|C1ANL1|C1ANL1_MYCBT Tax_Id=561275 (bioB)SubName: Full=Biotin ...   604   e-171
tr|A2VI81|A2VI81_MYCTU Tax_Id=348776 SubName: Full=Biotin synthe...   604   e-171
sp|A0QHJ1|BIOB_MYCA1 Tax_Id=243243 (bioB)RecName: Full=Biotin sy...   601   e-170
sp|Q740Q9|BIOB_MYCPA Tax_Id=1770 (bioB)RecName: Full=Biotin synt...   600   e-170
sp|B2HQ93|BIOB_MYCMM Tax_Id=216594 (bioB)RecName: Full=Biotin sy...   598   e-169
sp|A0PP05|BIOB_MYCUA Tax_Id=362242 (bioB)RecName: Full=Biotin sy...   598   e-169
sp|A1T8V0|BIOB_MYCVP Tax_Id=350058 (bioB)RecName: Full=Biotin sy...   580   e-164
sp|Q1B7F4|BIOB_MYCSS Tax_Id=164756 (bioB)RecName: Full=Biotin sy...   580   e-164
sp|A1UHL9|BIOB_MYCSK Tax_Id=189918 (bioB)RecName: Full=Biotin sy...   580   e-164
sp|A3Q142|BIOB_MYCSJ Tax_Id=164757 (bioB)RecName: Full=Biotin sy...   580   e-164
sp|B1MBZ3|BIOB_MYCA9 Tax_Id=561007 (bioB)RecName: Full=Biotin sy...   577   e-163
tr|D0LA15|D0LA15_9ACTO Tax_Id=526226 SubName: Full=Biotin syntha...   573   e-161
sp|A0QX70|BIOB_MYCS2 Tax_Id=246196 (bioB)RecName: Full=Biotin sy...   572   e-161
sp|Q0SHW6|BIOB_RHOSR Tax_Id=101510 (bioB)RecName: Full=Biotin sy...   571   e-161
sp|A4T9L9|BIOB_MYCGI Tax_Id=350054 (bioB)RecName: Full=Biotin sy...   571   e-161
tr|C1AU09|C1AU09_RHOOB Tax_Id=632772 (bioB)SubName: Full=Biotin ...   568   e-160
sp|Q5YYR3|BIOB_NOCFA Tax_Id=37329 (bioB)RecName: Full=Biotin syn...   566   e-159
tr|C1A0R1|C1A0R1_RHOE4 Tax_Id=234621 (bioB)SubName: Full=Biotin ...   562   e-158
tr|C3JIY2|C3JIY2_RHOER Tax_Id=596309 (bioB)SubName: Full=Biotin ...   562   e-158
tr|C2APS7|C2APS7_TSUPA Tax_Id=521096 SubName: Full=Biotin synthe...   556   e-156
tr|C2AC84|C2AC84_THECU Tax_Id=471852 SubName: Full=Biotin syntha...   518   e-145
tr|C7QDW0|C7QDW0_CATAD Tax_Id=479433 SubName: Full=Biotin syntha...   511   e-143
sp|A8LUR1|BIOB_SALAI Tax_Id=391037 (bioB)RecName: Full=Biotin sy...   503   e-140
sp|A4X585|BIOB_SALTO Tax_Id=369723 (bioB)RecName: Full=Biotin sy...   501   e-140
tr|C4EDN7|C4EDN7_STRRS Tax_Id=479432 SubName: Full=Biotin synthe...   501   e-140
tr|C4LI85|C4LI85_CORK4 Tax_Id=645127 (bioB)SubName: Full=Biotin ...   500   e-139
tr|C1WFW1|C1WFW1_9ACTO Tax_Id=479435 SubName: Full=Biotin synthe...   498   e-139
tr|C4REH6|C4REH6_9ACTO Tax_Id=219305 SubName: Full=Biotin syntha...   497   e-139
sp|Q2J6H8|BIOB1_FRASC Tax_Id=106370 (bioB1)RecName: Full=Biotin ...   496   e-138
sp|A8L2N0|BIOB_FRASN Tax_Id=298653 (bioB)RecName: Full=Biotin sy...   495   e-138
sp|Q0RD46|BIOB_FRAAA Tax_Id=326424 (bioB)RecName: Full=Biotin sy...   494   e-138
sp|B1VF77|BIOB_CORU7 Tax_Id=504474 (bioB)RecName: Full=Biotin sy...   491   e-137
sp|Q6NKC7|BIOB1_CORDI Tax_Id=1717 (bioB1)RecName: Full=Biotin sy...   491   e-137
tr|C7MZ14|C7MZ14_SACVD Tax_Id=471857 SubName: Full=Biotin synthe...   491   e-137
sp|Q4JWG3|BIOB_CORJK Tax_Id=306537 (bioB)RecName: Full=Biotin sy...   487   e-135
tr|C6WDB5|C6WDB5_ACTMD Tax_Id=446462 SubName: Full=Biotin syntha...   487   e-135
tr|C8RRK5|C8RRK5_CORJE Tax_Id=525262 (bioB)SubName: Full=Biotin ...   485   e-135
tr|C0E1U1|C0E1U1_9CORY Tax_Id=566549 SubName: Full=Putative unch...   479   e-133
tr|C5VAB0|C5VAB0_9CORY Tax_Id=553207 (bioB)SubName: Full=Biotin ...   476   e-132
sp|P46396|BIOB_CORGL Tax_Id=1718 (bioB)RecName: Full=Biotin synt...   471   e-131
sp|A4QA10|BIOB_CORGB Tax_Id=340322 (bioB)RecName: Full=Biotin sy...   471   e-131

>sp|P46715|BIOB_MYCLE Tax_Id=1769 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium leprae]
          Length = 345

 Score =  686 bits (1769), Expect = 0.0
 Identities = 344/345 (99%), Positives = 345/345 (100%)

Query: 1   VTQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR 60
           +TQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR
Sbjct: 1   MTQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR 60

Query: 61  MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA 120
           MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA
Sbjct: 61  MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA 120

Query: 121 TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH 180
           TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH
Sbjct: 121 TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH 180

Query: 181 NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL 240
           NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL
Sbjct: 181 NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL 240

Query: 241 GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA 300
           GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA
Sbjct: 241 GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA 300

Query: 301 KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL
Sbjct: 301 KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345


>sp|B8ZR86|BIOB_MYCLB Tax_Id=561304 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium leprae]
          Length = 345

 Score =  686 bits (1769), Expect = 0.0
 Identities = 344/345 (99%), Positives = 345/345 (100%)

Query: 1   VTQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR 60
           +TQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR
Sbjct: 1   MTQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR 60

Query: 61  MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA 120
           MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA
Sbjct: 61  MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA 120

Query: 121 TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH 180
           TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH
Sbjct: 121 TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH 180

Query: 181 NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL 240
           NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL
Sbjct: 181 NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL 240

Query: 241 GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA 300
           GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA
Sbjct: 241 GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA 300

Query: 301 KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL
Sbjct: 301 KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345


>tr|A4KHB4|A4KHB4_MYCTU Tax_Id=395095 SubName: Full=Biotin
           synthetase bioB;[Mycobacterium tuberculosis str.
           Haarlem]
          Length = 365

 Score =  605 bits (1560), Expect = e-171
 Identities = 304/349 (87%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           VTQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 17  VTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 76

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 77  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 136

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 137 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 196

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 197 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 256

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 257 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 316

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 317 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 365


>sp|P0A506|BIOB_MYCTU Tax_Id=1773 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium tuberculosis]
          Length = 349

 Score =  604 bits (1557), Expect = e-171
 Identities = 303/349 (86%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           +TQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 1   MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 60

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 61  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 120

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 121 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 180

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 181 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 240

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 241 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 300

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 301 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 349


>sp|A5WMR0|BIOB_MYCTF Tax_Id=336982 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium tuberculosis]
          Length = 349

 Score =  604 bits (1557), Expect = e-171
 Identities = 303/349 (86%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           +TQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 1   MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 60

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 61  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 120

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 121 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 180

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 181 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 240

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 241 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 300

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 301 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 349


>sp|A5U2U5|BIOB_MYCTA Tax_Id=419947 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium tuberculosis]
          Length = 349

 Score =  604 bits (1557), Expect = e-171
 Identities = 303/349 (86%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           +TQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 1   MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 60

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 61  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 120

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 121 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 180

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 181 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 240

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 241 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 300

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 301 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 349


>sp|A1KJ05|BIOB_MYCBP Tax_Id=410289 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium bovis]
          Length = 349

 Score =  604 bits (1557), Expect = e-171
 Identities = 303/349 (86%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           +TQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 1   MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 60

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 61  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 120

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 121 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 180

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 181 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 240

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 241 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 300

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 301 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 349


>sp|P0A507|BIOB_MYCBO Tax_Id=1765 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium bovis]
          Length = 349

 Score =  604 bits (1557), Expect = e-171
 Identities = 303/349 (86%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           +TQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 1   MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 60

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 61  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 120

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 121 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 180

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 181 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 240

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 241 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 300

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 301 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 349


>tr|C6DSL9|C6DSL9_MYCTK Tax_Id=478434 SubName: Full=Biotin
           synthetase bioB;[Mycobacterium tuberculosis]
          Length = 349

 Score =  604 bits (1557), Expect = e-171
 Identities = 303/349 (86%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           +TQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 1   MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 60

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 61  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 120

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 121 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 180

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 181 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 240

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 241 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 300

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 301 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 349


>tr|C1ANL1|C1ANL1_MYCBT Tax_Id=561275 (bioB)SubName: Full=Biotin
           synthase; EC=2.8.1.6;[Mycobacterium bovis]
          Length = 349

 Score =  604 bits (1557), Expect = e-171
 Identities = 303/349 (86%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           +TQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 1   MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 60

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 61  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 120

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 121 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 180

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 181 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 240

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 241 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 300

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 301 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 349


>tr|A2VI81|A2VI81_MYCTU Tax_Id=348776 SubName: Full=Biotin
           synthetase bioB;[Mycobacterium tuberculosis C]
          Length = 349

 Score =  604 bits (1557), Expect = e-171
 Identities = 303/349 (86%), Positives = 324/349 (92%), Gaps = 4/349 (1%)

Query: 1   VTQAGTRSTNGDTE----NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALA 56
           +TQA TR TN   +    N+DIL  ARQQVL+RGEGL++DQVL +L LPDDRLEELLALA
Sbjct: 1   MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALA 60

Query: 57  HDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTA 116
           H+VRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTA
Sbjct: 61  HEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTA 120

Query: 117 KSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVH 176
           KSGATEFCIVAAVRGPDERLM+QVAAGIEAIRNEVEINIACSLGMLT EQV+QL+  GVH
Sbjct: 121 KSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVH 180

Query: 177 RYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALE 236
           RYNHNLETARSFF NVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGET++QRAEFA E
Sbjct: 181 RYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAE 240

Query: 237 LAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLG 296
           LAELGPDEVPLNFLNPRPGTPF  LEVMP  +ALK+VAAFRLALPRT+LRFAGGREITLG
Sbjct: 241 LAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLG 300

Query: 297 DLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           DLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LLD+LQMP+KALNASL
Sbjct: 301 DLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL 349


>sp|A0QHJ1|BIOB_MYCA1 Tax_Id=243243 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium avium]
          Length = 345

 Score =  601 bits (1550), Expect = e-170
 Identities = 302/345 (87%), Positives = 322/345 (93%)

Query: 1   VTQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR 60
           +TQA TR T     + DILA AR+QVLE G+GLSRDQVLQ+L LPDDRL++LLALAH+VR
Sbjct: 1   MTQAATRPTAETGNDEDILAVARRQVLEGGQGLSRDQVLQVLRLPDDRLDDLLALAHEVR 60

Query: 61  MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA 120
           MRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSA LDI SLVEAAKQTAKSGA
Sbjct: 61  MRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSARLDIPSLVEAAKQTAKSGA 120

Query: 121 TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH 180
           TEFCIVAAVRGPDERL++QVAAGIEAIRNEVEINIACSLGMLT EQVEQL+ +GVHRYNH
Sbjct: 121 TEFCIVAAVRGPDERLLAQVAAGIEAIRNEVEINIACSLGMLTAEQVEQLAEMGVHRYNH 180

Query: 181 NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL 240
           NLETARSFF NVVTTHTWEERW TLSMVRDAGMEVCCGGILGMGET+EQRAEFA ELAEL
Sbjct: 181 NLETARSFFPNVVTTHTWEERWDTLSMVRDAGMEVCCGGILGMGETLEQRAEFAAELAEL 240

Query: 241 GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA 300
           GPDEVPLNFLNPRPGTPFG LEVMP +EALKSVAAFRLALPRT+LRFAGGREITLGDLGA
Sbjct: 241 GPDEVPLNFLNPRPGTPFGDLEVMPATEALKSVAAFRLALPRTMLRFAGGREITLGDLGA 300

Query: 301 KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           K+G+LGGINAVIVGNYLTTLGRPAE+DL LLDDLQMP+K LNASL
Sbjct: 301 KKGILGGINAVIVGNYLTTLGRPAESDLELLDDLQMPLKGLNASL 345


>sp|Q740Q9|BIOB_MYCPA Tax_Id=1770 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium paratuberculosis]
          Length = 344

 Score =  600 bits (1548), Expect = e-170
 Identities = 302/345 (87%), Positives = 323/345 (93%), Gaps = 1/345 (0%)

Query: 1   VTQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR 60
           +TQA TR T  +  N DILA AR+QVLE G+GLSRDQVLQ+L LPDDRL++LLALAH+VR
Sbjct: 1   MTQAATRPT-AEIGNEDILAVARRQVLEGGQGLSRDQVLQVLRLPDDRLDDLLALAHEVR 59

Query: 61  MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA 120
           MRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSA LDI SLVEAAKQTAKSGA
Sbjct: 60  MRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSARLDIPSLVEAAKQTAKSGA 119

Query: 121 TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH 180
           TEFCIVAAVRGPDERL++QVAAGIEA+RNEVEINIACSLGMLT EQVEQL+ +GVHRYNH
Sbjct: 120 TEFCIVAAVRGPDERLLAQVAAGIEAVRNEVEINIACSLGMLTAEQVEQLAEMGVHRYNH 179

Query: 181 NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL 240
           NLETARSFF NVVTTHTWEERW TLSMVRDAGMEVCCGGILGMGET+EQRAEFA ELAEL
Sbjct: 180 NLETARSFFPNVVTTHTWEERWDTLSMVRDAGMEVCCGGILGMGETLEQRAEFAAELAEL 239

Query: 241 GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA 300
           GPDEVPLNFLNPRPGTPFG LEVMP +EALKSVAAFRLALPRT+LRFAGGREITLGDLGA
Sbjct: 240 GPDEVPLNFLNPRPGTPFGDLEVMPATEALKSVAAFRLALPRTMLRFAGGREITLGDLGA 299

Query: 301 KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           K+G+LGGINAVIVGNYLTTLGRPAE+DL LLDDLQMP+K LNASL
Sbjct: 300 KKGILGGINAVIVGNYLTTLGRPAESDLELLDDLQMPLKGLNASL 344


>sp|B2HQ93|BIOB_MYCMM Tax_Id=216594 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium marinum]
          Length = 349

 Score =  598 bits (1542), Expect = e-169
 Identities = 302/350 (86%), Positives = 324/350 (92%), Gaps = 6/350 (1%)

Query: 1   VTQAGTRSTN-----GDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLAL 55
           +TQA TR +N     G TE  DILA ARQQVLERGEGL+++QVLQ+L L +DRLEELLAL
Sbjct: 1   MTQAATRPSNDAGQDGVTE-PDILAVARQQVLERGEGLNQEQVLQVLQLSEDRLEELLAL 59

Query: 56  AHDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQT 115
           AHDVRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQT
Sbjct: 60  AHDVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFSSPVRSAWLDIPSLVEAAKQT 119

Query: 116 AKSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGV 175
           AKSGATEFCIVAAVRGPD RL+SQVAAGIEAIRNEVEIN+ACSLGMLT EQVEQL+ +GV
Sbjct: 120 AKSGATEFCIVAAVRGPDARLLSQVAAGIEAIRNEVEINVACSLGMLTAEQVEQLAAMGV 179

Query: 176 HRYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFAL 235
           HRYNHNLETARS+FTNVVTTHTWEERWQTL+MVRDAGMEVCCGGILGMGET+EQRAEFA 
Sbjct: 180 HRYNHNLETARSYFTNVVTTHTWEERWQTLTMVRDAGMEVCCGGILGMGETLEQRAEFAA 239

Query: 236 ELAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITL 295
            LAEL PDEVPLNFLNPRPGTPFG LEV+P  EALK+V AFRLALPRT+LRFAGGREITL
Sbjct: 240 NLAELDPDEVPLNFLNPRPGTPFGDLEVLPAGEALKAVGAFRLALPRTMLRFAGGREITL 299

Query: 296 GDLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           GDLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LL+DLQMP+KALNASL
Sbjct: 300 GDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLEDLQMPLKALNASL 349


>sp|A0PP05|BIOB_MYCUA Tax_Id=362242 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium ulcerans]
          Length = 350

 Score =  598 bits (1541), Expect = e-169
 Identities = 302/350 (86%), Positives = 323/350 (92%), Gaps = 6/350 (1%)

Query: 1   VTQAGTRSTN-----GDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLAL 55
           VTQA TR +N     G TE  DILA ARQQVLERGEGL+++QVLQ+L L +DRLEELL L
Sbjct: 2   VTQAATRPSNDAGQDGVTE-PDILAVARQQVLERGEGLNQEQVLQVLQLSEDRLEELLVL 60

Query: 56  AHDVRMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQT 115
           AHDVRMRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQT
Sbjct: 61  AHDVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFSSPVRSAWLDIPSLVEAAKQT 120

Query: 116 AKSGATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGV 175
           AKSGATEFCIVAAVRGPD RL+SQVAAGIEAIRNEVEIN+ACSLGMLT EQVEQL+ +GV
Sbjct: 121 AKSGATEFCIVAAVRGPDARLLSQVAAGIEAIRNEVEINVACSLGMLTAEQVEQLAAMGV 180

Query: 176 HRYNHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFAL 235
           HRYNHNLETARS+FTNVVTTHTWEERWQTL+MVRDAGMEVCCGGILGMGET+EQRAEFA 
Sbjct: 181 HRYNHNLETARSYFTNVVTTHTWEERWQTLTMVRDAGMEVCCGGILGMGETLEQRAEFAA 240

Query: 236 ELAELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITL 295
            LAEL PDEVPLNFLNPRPGTPFG LEV+P  EALK+V AFRLALPRT+LRFAGGREITL
Sbjct: 241 NLAELDPDEVPLNFLNPRPGTPFGDLEVLPAGEALKAVGAFRLALPRTMLRFAGGREITL 300

Query: 296 GDLGAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           GDLGAK+G+LGGINAVIVGNYLTTLGRPAEADL LL+DLQMP+KALNASL
Sbjct: 301 GDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLEDLQMPLKALNASL 350


>sp|A1T8V0|BIOB_MYCVP Tax_Id=350058 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium vanbaalenii]
          Length = 331

 Score =  580 bits (1496), Expect = e-164
 Identities = 287/330 (86%), Positives = 311/330 (94%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           TDILA AR+QVL RGEGL +DQ LQ+L LPDDRL++LLALAH+VRM WCGP+VE+EGIIS
Sbjct: 2   TDILAVAREQVLVRGEGLDQDQTLQVLQLPDDRLDDLLALAHEVRMAWCGPDVEVEGIIS 61

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTAK+GATEFCIVAAVRGPDER
Sbjct: 62  LKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           L++QVAAGIEAIRNEV+I IACSLGMLT +QVE+LS +GVHRYNHNLETARSFFTNVVTT
Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTQDQVERLSEMGVHRYNHNLETARSFFTNVVTT 181

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           H+WEERW TL MVR+AGMEVCCGGILGMGET+EQRAEFA  LAEL P EVPLNFLNPRPG
Sbjct: 182 HSWEERWDTLQMVREAGMEVCCGGILGMGETLEQRAEFAANLAELDPHEVPLNFLNPRPG 241

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG LEV+P SEALK+VAAFRLALPRT+LRFAGGREITLGDLGAKQG+LGGINAVIVGN
Sbjct: 242 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKQGILGGINAVIVGN 301

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAEADL+LLDDLQMPIKALNA+L
Sbjct: 302 YLTTLGRPAEADLQLLDDLQMPIKALNATL 331


>sp|Q1B7F4|BIOB_MYCSS Tax_Id=164756 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium sp.]
          Length = 331

 Score =  580 bits (1495), Expect = e-164
 Identities = 286/330 (86%), Positives = 311/330 (94%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           +DILA AR+QVLERG GL++DQ LQ+L LPDDRL++LLALAH+VRM WCGP+VE+EGIIS
Sbjct: 2   SDILAVAREQVLERGVGLNQDQTLQVLQLPDDRLDDLLALAHEVRMAWCGPDVEVEGIIS 61

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVRSAWLD+ SLVEAAKQTAK+GATEFCIVAAVRGPDER
Sbjct: 62  LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           L++QVAAGIEAIRNEV+I IACSLGMLT EQVE+LS +GVHRYNHNLETARSFFTNVVTT
Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTAEQVERLSEMGVHRYNHNLETARSFFTNVVTT 181

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTWEERW TL MVR+AGMEVCCGGILGMGET+EQRAEFA  LAEL P EVPLNFLNPRPG
Sbjct: 182 HTWEERWDTLRMVREAGMEVCCGGILGMGETLEQRAEFAANLAELDPHEVPLNFLNPRPG 241

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG LEV+P +EALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+G+LGGINAVIVGN
Sbjct: 242 TPFGDLEVLPAAEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 301

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAEADL LLDDLQMPIKALNASL
Sbjct: 302 YLTTLGRPAEADLELLDDLQMPIKALNASL 331


>sp|A1UHL9|BIOB_MYCSK Tax_Id=189918 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium sp.]
          Length = 331

 Score =  580 bits (1495), Expect = e-164
 Identities = 286/330 (86%), Positives = 311/330 (94%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           +DILA AR+QVLERG GL++DQ LQ+L LPDDRL++LLALAH+VRM WCGP+VE+EGIIS
Sbjct: 2   SDILAVAREQVLERGVGLNQDQTLQVLQLPDDRLDDLLALAHEVRMAWCGPDVEVEGIIS 61

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVRSAWLD+ SLVEAAKQTAK+GATEFCIVAAVRGPDER
Sbjct: 62  LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           L++QVAAGIEAIRNEV+I IACSLGMLT EQVE+LS +GVHRYNHNLETARSFFTNVVTT
Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTAEQVERLSEMGVHRYNHNLETARSFFTNVVTT 181

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTWEERW TL MVR+AGMEVCCGGILGMGET+EQRAEFA  LAEL P EVPLNFLNPRPG
Sbjct: 182 HTWEERWDTLRMVREAGMEVCCGGILGMGETLEQRAEFAANLAELDPHEVPLNFLNPRPG 241

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG LEV+P +EALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+G+LGGINAVIVGN
Sbjct: 242 TPFGDLEVLPAAEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 301

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAEADL LLDDLQMPIKALNASL
Sbjct: 302 YLTTLGRPAEADLELLDDLQMPIKALNASL 331


>sp|A3Q142|BIOB_MYCSJ Tax_Id=164757 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium sp.]
          Length = 331

 Score =  580 bits (1495), Expect = e-164
 Identities = 286/330 (86%), Positives = 311/330 (94%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           +DILA AR+QVLERG GL++DQ LQ+L LPDDRL++LLALAH+VRM WCGP+VE+EGIIS
Sbjct: 2   SDILAVAREQVLERGVGLNQDQTLQVLQLPDDRLDDLLALAHEVRMAWCGPDVEVEGIIS 61

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVRSAWLD+ SLVEAAKQTAK+GATEFCIVAAVRGPDER
Sbjct: 62  LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           L++QVAAGIEAIRNEV+I IACSLGMLT EQVE+LS +GVHRYNHNLETARSFFTNVVTT
Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTAEQVERLSEMGVHRYNHNLETARSFFTNVVTT 181

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTWEERW TL MVR+AGMEVCCGGILGMGET+EQRAEFA  LAEL P EVPLNFLNPRPG
Sbjct: 182 HTWEERWDTLRMVREAGMEVCCGGILGMGETLEQRAEFAANLAELDPHEVPLNFLNPRPG 241

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG LEV+P +EALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+G+LGGINAVIVGN
Sbjct: 242 TPFGDLEVLPAAEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 301

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAEADL LLDDLQMPIKALNASL
Sbjct: 302 YLTTLGRPAEADLELLDDLQMPIKALNASL 331


>sp|B1MBZ3|BIOB_MYCA9 Tax_Id=561007 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium abscessus]
          Length = 342

 Score =  577 bits (1487), Expect = e-163
 Identities = 284/331 (85%), Positives = 312/331 (94%)

Query: 15  NTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGII 74
           + D+LA AR+QVLE+G GL+++QVL++L LPDDRLEELLALAH+VRMRWCGPEVE+EGII
Sbjct: 12  DADVLAVAREQVLEQGVGLTQEQVLRVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGII 71

Query: 75  SLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDE 134
           SLKTGGCPEDCHFCSQSGLF SPVRSAWLDI SLVEAAKQTAKSGATEFCIVAAVRGPDE
Sbjct: 72  SLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDE 131

Query: 135 RLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVT 194
           RL++QVAAGIEAIRNEV+I IACSLGMLT EQV++LS +GVHRYNHNLETA+S F NVVT
Sbjct: 132 RLLAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDRLSAMGVHRYNHNLETAKSHFPNVVT 191

Query: 195 THTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRP 254
           TH+WEERW TL MVR+AGMEVCCGGILGMGET+EQRAEFA  LAEL PDEVPLNFLNPRP
Sbjct: 192 THSWEERWDTLKMVREAGMEVCCGGILGMGETLEQRAEFAANLAELEPDEVPLNFLNPRP 251

Query: 255 GTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVG 314
           GTPFG LEV+P S+AL++VAAFRLALPRT+LRFAGGREITLGDLGAKQG+LGGINAVIVG
Sbjct: 252 GTPFGDLEVLPASDALRAVAAFRLALPRTMLRFAGGREITLGDLGAKQGILGGINAVIVG 311

Query: 315 NYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           NYLTTLGRPAEADL LLDDLQMPIKALN+SL
Sbjct: 312 NYLTTLGRPAEADLELLDDLQMPIKALNSSL 342


>tr|D0LA15|D0LA15_9ACTO Tax_Id=526226 SubName: Full=Biotin synthase;
           EC=2.8.1.6;[Gordonia bronchialis DSM 43247]
          Length = 345

 Score =  573 bits (1477), Expect = e-161
 Identities = 289/345 (83%), Positives = 308/345 (89%)

Query: 1   VTQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR 60
           +TQA   S    TE+ DILA AR QVLERGE L RDQVL +L LPDDRL ELL LAHDVR
Sbjct: 1   MTQATVASGTVVTESDDILAVARAQVLERGEALDRDQVLTVLRLPDDRLTELLQLAHDVR 60

Query: 61  MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA 120
           MRWCGPEVE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAW+DI SLVEAAKQTAK+GA
Sbjct: 61  MRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWIDIPSLVEAAKQTAKTGA 120

Query: 121 TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH 180
           TEFCIVAAVRGPD+RL+SQVAAGIEAIRNEV+I IACSLGMLT EQV+QL  +GVHRYNH
Sbjct: 121 TEFCIVAAVRGPDKRLLSQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLRDMGVHRYNH 180

Query: 181 NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL 240
           NLETARS F NVVTTHTWEERW TL MVRDAGMEVCCGGILGMGE++EQRAEFA +LA L
Sbjct: 181 NLETARSHFPNVVTTHTWEERWDTLRMVRDAGMEVCCGGILGMGESLEQRAEFAADLASL 240

Query: 241 GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA 300
            PDEVPLNFLNPRPGTPFG LEV+P SEALK+VAAFRLALPRTILRFAGGREITLGDLGA
Sbjct: 241 EPDEVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTILRFAGGREITLGDLGA 300

Query: 301 KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           KQG+LGGINAVIVGNYLTTLGRPAE DL LL DL MPIK LN ++
Sbjct: 301 KQGILGGINAVIVGNYLTTLGRPAEDDLDLLSDLSMPIKTLNDTI 345


>sp|A0QX70|BIOB_MYCS2 Tax_Id=246196 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium smegmatis]
          Length = 353

 Score =  572 bits (1475), Expect = e-161
 Identities = 281/337 (83%), Positives = 311/337 (92%)

Query: 9   TNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEV 68
           T      TD+L  AR+QVLERG GL + Q LQ+L LPD+RL++LL+LAH+VRMRWCGP+V
Sbjct: 17  TQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDV 76

Query: 69  EIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAA 128
           E+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLD+ SLVEAAKQTAK+GATEFCIVAA
Sbjct: 77  EVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAA 136

Query: 129 VRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSF 188
           VRGPDERL++QVAAGIEAIRNEV+I IACSLGMLT EQV++L+ +GVHRYNHNLETARSF
Sbjct: 137 VRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSF 196

Query: 189 FTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLN 248
           F NVVTTHTWEERW TL+MVR+AGMEVCCGGILGMGET+EQRAEFA  LAEL P EVPLN
Sbjct: 197 FPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLN 256

Query: 249 FLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGI 308
           FLNPRPGTPFG LEV+P SEALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+G+LGGI
Sbjct: 257 FLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGI 316

Query: 309 NAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           NAVIVGNYLTTLGRPAEADL+LLDDLQMPIKALNA+L
Sbjct: 317 NAVIVGNYLTTLGRPAEADLQLLDDLQMPIKALNATL 353


>sp|Q0SHW6|BIOB_RHOSR Tax_Id=101510 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Rhodococcus sp.]
          Length = 337

 Score =  571 bits (1471), Expect = e-161
 Identities = 283/330 (85%), Positives = 307/330 (93%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           TDILA AR+QVLERG+ L+  QVL++L LPDDRLEELLALAHDVRM+WCGPEVE+EGIIS
Sbjct: 8   TDILALAREQVLERGDALNESQVLEVLQLPDDRLEELLALAHDVRMKWCGPEVEVEGIIS 67

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVR+AWLDI SLVEAAKQTAKSGA+EFCIVAAVRGPDER
Sbjct: 68  LKTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGASEFCIVAAVRGPDER 127

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           L++QVAAGIEAIRNEV+I IACSLGMLT EQV+QL+ +GVHRYNHNLET++S F NVVTT
Sbjct: 128 LLAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTT 187

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTW+ERW TL MVR+AGMEVCCGGILGMGE++EQRAEFA  LAEL PDEVPLNFLNPRPG
Sbjct: 188 HTWDERWNTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPG 247

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG LEV+P SEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQG+LGGINAVIVGN
Sbjct: 248 TPFGDLEVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGN 307

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAE DL LL DLQMPIKALN +L
Sbjct: 308 YLTTLGRPAEQDLDLLVDLQMPIKALNDTL 337


>sp|A4T9L9|BIOB_MYCGI Tax_Id=350054 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Mycobacterium gilvum]
          Length = 331

 Score =  571 bits (1471), Expect = e-161
 Identities = 282/330 (85%), Positives = 310/330 (93%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           +DILA AR+QVLERG GL +DQ LQ+L LPDDRL+ELLALAH+VRM  CGP+VE+EGIIS
Sbjct: 2   SDILAVAREQVLERGVGLDQDQTLQVLQLPDDRLDELLALAHEVRMAHCGPDVEVEGIIS 61

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVRSAWLD+ SLVEAAKQTAK+GATEFCIVAAVRGPDER
Sbjct: 62  LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           L++QVAAGIEAIRNEV+I IACSLGMLT +QVE+LS +GVHRYNHNLETARSFFTNVVTT
Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTQDQVERLSAMGVHRYNHNLETARSFFTNVVTT 181

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           H+WEERW+TL MVR+AGMEVCCGGILGMGE++ QRAEFA  LAEL P EVPLNFLNPRPG
Sbjct: 182 HSWEERWETLQMVREAGMEVCCGGILGMGESLGQRAEFAANLAELDPHEVPLNFLNPRPG 241

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG LEV+P +EALK+VAAFRLALPRT+LRFAGGREITLGDLGAKQG+LGGINAVIVGN
Sbjct: 242 TPFGDLEVLPATEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKQGILGGINAVIVGN 301

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAEADL+LLDDLQMPIKALNA+L
Sbjct: 302 YLTTLGRPAEADLQLLDDLQMPIKALNATL 331


>tr|C1AU09|C1AU09_RHOOB Tax_Id=632772 (bioB)SubName: Full=Biotin
           synthase; EC=2.8.1.6;[Rhodococcus opacus]
          Length = 337

 Score =  568 bits (1463), Expect = e-160
 Identities = 282/330 (85%), Positives = 306/330 (92%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           TDILA AR+QVLERG+ L+  QVL++L LPDDRLEELLALAHDVRM+WCGPEVE+EGIIS
Sbjct: 8   TDILALAREQVLERGDALNEAQVLEVLQLPDDRLEELLALAHDVRMKWCGPEVEVEGIIS 67

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVR+AWLDI SLVEAAKQTAKSGA+EFCIVAAVRGPDER
Sbjct: 68  LKTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGASEFCIVAAVRGPDER 127

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           L++QVAAGIEAIRNEV+I IACSLGMLT EQV+QL+ +GVHRYNHNLET++S F NVVTT
Sbjct: 128 LLAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTT 187

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTW+ERW TL MVR+AGMEVCCGGILGMGE++ QRAEFA  LAEL PDEVPLNFLNPRPG
Sbjct: 188 HTWDERWNTLRMVREAGMEVCCGGILGMGESLAQRAEFAANLAELEPDEVPLNFLNPRPG 247

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG LEV+P SEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQG+LGGINAVIVGN
Sbjct: 248 TPFGDLEVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGN 307

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAE DL LL DLQMPIKALN +L
Sbjct: 308 YLTTLGRPAEQDLDLLVDLQMPIKALNDTL 337


>sp|Q5YYR3|BIOB_NOCFA Tax_Id=37329 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Nocardia farcinica]
          Length = 337

 Score =  566 bits (1458), Expect = e-159
 Identities = 279/330 (84%), Positives = 306/330 (92%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           TDIL  AR+QVLERGEGL++DQ L +L L DDRLEELL LAH+VRM+WCGPEVE+EGIIS
Sbjct: 8   TDILEIAREQVLERGEGLTQDQTLAVLRLGDDRLEELLGLAHEVRMKWCGPEVEVEGIIS 67

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVR+AWLDI SLVEAAKQTAK+GATEFCIVAAVRGPD R
Sbjct: 68  LKTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKTGATEFCIVAAVRGPDAR 127

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           LM+QVAAG+EAIRNEV+I +ACSLGMLT EQV+QL+ +GVHRYNHNLETA+S F NVVTT
Sbjct: 128 LMAQVAAGVEAIRNEVDIQVACSLGMLTQEQVDQLAAMGVHRYNHNLETAKSHFPNVVTT 187

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTWEERW TL MVR+AGMEVCCGGILGMGET+EQRAEFA +LAEL PDEVPLNFLNPRPG
Sbjct: 188 HTWEERWDTLRMVREAGMEVCCGGILGMGETLEQRAEFAAQLAELEPDEVPLNFLNPRPG 247

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG LEV+P SEALK+VAAFRLALPRTILRFAGGREITLGDLGAKQG+LGGINAVIVGN
Sbjct: 248 TPFGDLEVLPASEALKAVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGN 307

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAE+DL LL +L+MPIKALN +L
Sbjct: 308 YLTTLGRPAESDLDLLGELKMPIKALNETL 337


>tr|C1A0R1|C1A0R1_RHOE4 Tax_Id=234621 (bioB)SubName: Full=Biotin
           synthase; EC=2.8.1.6;[Rhodococcus erythropolis]
          Length = 342

 Score =  562 bits (1449), Expect = e-158
 Identities = 280/329 (85%), Positives = 303/329 (92%)

Query: 17  DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISL 76
           DIL QAR+QVLERG GL+  QVL +L L DDRLE+LLALAHDVRM+WCGPEVE+EGIISL
Sbjct: 14  DILDQAREQVLERGVGLTESQVLDVLRLDDDRLEDLLALAHDVRMKWCGPEVEVEGIISL 73

Query: 77  KTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERL 136
           KTGGCPEDCHFCSQSGLF SPVR+AWLDI SLVEAAKQTAKSGATEFCIVAAVRGPD RL
Sbjct: 74  KTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDARL 133

Query: 137 MSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTH 196
           ++QVAAGIEAIRNEV+I IACSLGMLT EQV+QL+ +GVHRYNHNLET++S F NVVTTH
Sbjct: 134 LAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTTH 193

Query: 197 TWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGT 256
           +WEERW TL MVR+AGMEVCCGGILGMGE++EQRAEFA  LAEL PDEVPLNFLNPRPGT
Sbjct: 194 SWEERWNTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPGT 253

Query: 257 PFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNY 316
           PFG L+V+P SEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQG+LGGINAVIVGNY
Sbjct: 254 PFGDLDVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGNY 313

Query: 317 LTTLGRPAEADLRLLDDLQMPIKALNASL 345
           LTTLGRPAE DL LL DLQMPIKALN +L
Sbjct: 314 LTTLGRPAEKDLDLLVDLQMPIKALNDTL 342


>tr|C3JIY2|C3JIY2_RHOER Tax_Id=596309 (bioB)SubName: Full=Biotin
           synthase; EC=2.8.1.6;[Rhodococcus erythropolis SK121]
          Length = 342

 Score =  562 bits (1449), Expect = e-158
 Identities = 280/329 (85%), Positives = 303/329 (92%)

Query: 17  DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISL 76
           DIL QAR+QVLERG GL+  QVL +L L DDRLE+LLALAHDVRM+WCGPEVE+EGIISL
Sbjct: 14  DILDQAREQVLERGVGLTESQVLDVLRLDDDRLEDLLALAHDVRMKWCGPEVEVEGIISL 73

Query: 77  KTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERL 136
           KTGGCPEDCHFCSQSGLF SPVR+AWLDI SLVEAAKQTAKSGATEFCIVAAVRGPD RL
Sbjct: 74  KTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDARL 133

Query: 137 MSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTH 196
           ++QVAAGIEAIRNEV+I IACSLGMLT EQV+QL+ +GVHRYNHNLET++S F NVVTTH
Sbjct: 134 LAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTTH 193

Query: 197 TWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGT 256
           +WEERW TL MVR+AGMEVCCGGILGMGE++EQRAEFA  LAEL PDEVPLNFLNPRPGT
Sbjct: 194 SWEERWNTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPGT 253

Query: 257 PFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNY 316
           PFG L+V+P SEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQG+LGGINAVIVGNY
Sbjct: 254 PFGDLDVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGNY 313

Query: 317 LTTLGRPAEADLRLLDDLQMPIKALNASL 345
           LTTLGRPAE DL LL DLQMPIKALN +L
Sbjct: 314 LTTLGRPAEKDLDLLVDLQMPIKALNDTL 342


>tr|C2APS7|C2APS7_TSUPA Tax_Id=521096 SubName: Full=Biotin
           synthetase; EC=2.8.1.6;[Tsukamurella paurometabola DSM
           20162]
          Length = 335

 Score =  556 bits (1433), Expect = e-156
 Identities = 274/329 (83%), Positives = 305/329 (92%)

Query: 17  DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISL 76
           DI+  AR+QVLERGEGL+++QVL +L L DDRL+E+L LAH+VRM+WCGPEVE+EGIISL
Sbjct: 7   DIIDVAREQVLERGEGLNQEQVLAVLQLSDDRLDEVLQLAHEVRMKWCGPEVEVEGIISL 66

Query: 77  KTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERL 136
           KTGGCPEDCHFCSQSGLF SPVRSAW+DI SLVEAAKQTAK+GATEFCIVAAVRGPD+RL
Sbjct: 67  KTGGCPEDCHFCSQSGLFESPVRSAWIDIPSLVEAAKQTAKTGATEFCIVAAVRGPDKRL 126

Query: 137 MSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTH 196
           +SQVAAGIEAIRNEV+I IACSLGMLT EQV+QL  +GVHRYNHNLET+RS F NVVTTH
Sbjct: 127 LSQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLKDMGVHRYNHNLETSRSHFPNVVTTH 186

Query: 197 TWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGT 256
           TWEERW TL MVR+AGMEVCCGGILGMGE++EQRAEFA  LAEL PDEVPLNFLNPRPGT
Sbjct: 187 TWEERWDTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPGT 246

Query: 257 PFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNY 316
           PFG L+V+P +EALKSVAAFRLALPRTILRFAGGREITLGDLGA++G+LGGINAVIVGNY
Sbjct: 247 PFGDLDVLPAAEALKSVAAFRLALPRTILRFAGGREITLGDLGAEKGILGGINAVIVGNY 306

Query: 317 LTTLGRPAEADLRLLDDLQMPIKALNASL 345
           LTTLGRPAE DL LL++L+MPIKALN SL
Sbjct: 307 LTTLGRPAETDLDLLNELKMPIKALNDSL 335


>tr|C2AC84|C2AC84_THECU Tax_Id=471852 SubName: Full=Biotin synthase;
           EC=2.8.1.6;[Thermomonospora curvata DSM 43183]
          Length = 331

 Score =  518 bits (1333), Expect = e-145
 Identities = 250/330 (75%), Positives = 287/330 (86%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           TDIL  AR+QVLE G+GL  +QVLQ L LPDDRLE+LLALAH VRMRWCGPEVE+EGI+S
Sbjct: 2   TDILEVARRQVLEEGKGLDAEQVLQCLTLPDDRLEDLLALAHQVRMRWCGPEVEVEGIVS 61

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSG F SPVRS WL+I  LVEAAK+TAK+GATEFCIVAAVRGPDER
Sbjct: 62  LKTGGCPEDCHFCSQSGRFDSPVRSVWLNIPELVEAAKETAKTGATEFCIVAAVRGPDER 121

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           LM+QV  G++AI+  VEIN++CSLGMLT +Q E+L  +GVHRYNHNLETARS F NVVTT
Sbjct: 122 LMAQVREGVKAIQEAVEINVSCSLGMLTRQQAEELVAMGVHRYNHNLETARSHFPNVVTT 181

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTWEERW+T  +V++ GME+CCGGI+GMGETVEQRAEFA +LAEL PDEVPLNFL PRPG
Sbjct: 182 HTWEERWETCKLVKEVGMELCCGGIIGMGETVEQRAEFAAQLAELEPDEVPLNFLAPRPG 241

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPF    ++   EALK++ AFRLALPRT+LR+AGGREITLGDLG + GMLGGINA+IVGN
Sbjct: 242 TPFEHYGLVEGGEALKTIGAFRLALPRTLLRYAGGREITLGDLGTRSGMLGGINAIIVGN 301

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPAE DL LL +LQMPIKAL+ ++
Sbjct: 302 YLTTLGRPAEQDLELLSELQMPIKALSQTI 331


>tr|C7QDW0|C7QDW0_CATAD Tax_Id=479433 SubName: Full=Biotin synthase;
           EC=2.8.1.6;[Catenulispora acidiphila]
          Length = 341

 Score =  511 bits (1315), Expect = e-143
 Identities = 252/339 (74%), Positives = 291/339 (85%), Gaps = 1/339 (0%)

Query: 8   STNGDTENT-DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGP 66
           +T  DTEN  DILA AR QVL  G GL+ +QVL++L LPD+ L ELL LAH+VR +WCGP
Sbjct: 3   TTENDTENDLDILATARGQVLAEGVGLTEEQVLRVLRLPDEALPELLQLAHEVREKWCGP 62

Query: 67  EVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIV 126
           EVE+EGI+SLKTGGCPEDCHFCSQSGLF SPVR+AWL+I  LVEAAKQTA +GATEFCIV
Sbjct: 63  EVEVEGIVSLKTGGCPEDCHFCSQSGLFPSPVRAAWLNIPELVEAAKQTAATGATEFCIV 122

Query: 127 AAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETAR 186
           AAVRGPDERLM Q+  G++AI++ V+I +A SLGMLT EQV+ L+ +GVHRYNHNLETAR
Sbjct: 123 AAVRGPDERLMKQMREGVKAIQDAVDIQVAASLGMLTQEQVDDLADMGVHRYNHNLETAR 182

Query: 187 SFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVP 246
           S F NVVTTH+WEERW TL+MVRDAGMEVCCGGI+GMGET+EQRAEFA +LA L PDEVP
Sbjct: 183 SHFPNVVTTHSWEERWDTLTMVRDAGMEVCCGGIVGMGETLEQRAEFAAQLAALTPDEVP 242

Query: 247 LNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLG 306
           LNFLNPRPGTPFG +E +   EALK++AAFRLALPRTILR+AGGREITLGDLG +QG+LG
Sbjct: 243 LNFLNPRPGTPFGDMEPLSSQEALKTIAAFRLALPRTILRYAGGREITLGDLGTEQGLLG 302

Query: 307 GINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           GINAVIVGNYLTTLGR  + DL LL  L+MPIK L+ +L
Sbjct: 303 GINAVIVGNYLTTLGRSPQEDLALLTKLEMPIKELSKTL 341


>sp|A8LUR1|BIOB_SALAI Tax_Id=391037 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Salinispora arenicola]
          Length = 331

 Score =  503 bits (1295), Expect = e-140
 Identities = 245/329 (74%), Positives = 282/329 (85%)

Query: 17  DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISL 76
           +IL QAR QVLE G GL     L +L LPD+ L   L LAH+VRMRWCGPEVE+EGI+SL
Sbjct: 3   EILDQARTQVLENGVGLDEAGALAVLNLPDEHLPAALQLAHEVRMRWCGPEVEVEGIVSL 62

Query: 77  KTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERL 136
           KTGGCPEDCHFCSQSGLF SPVR+ WLDI SLVEAAKQTAK+GATEFCIVAAVRGPD+RL
Sbjct: 63  KTGGCPEDCHFCSQSGLFTSPVRAVWLDIPSLVEAAKQTAKTGATEFCIVAAVRGPDDRL 122

Query: 137 MSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTH 196
           M Q+  G+ AIR EV+I++A S+GMLT EQV++L  +GVHRYNHNLET RS+F NVVTTH
Sbjct: 123 MRQLREGVAAIRAEVDIHVAASVGMLTQEQVDELVEMGVHRYNHNLETCRSYFPNVVTTH 182

Query: 197 TWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGT 256
           +WEERW+TL MVR +GMEVCCGGILG+GETVEQRAEFA +LAEL P EVPLNFLNPRPGT
Sbjct: 183 SWEERWETLRMVRASGMEVCCGGILGLGETVEQRAEFAAQLAELDPHEVPLNFLNPRPGT 242

Query: 257 PFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNY 316
           P G   V+   +AL+++AAFRLA+PRTILR+AGGREITLGDLG + G+LGGINAVIVGNY
Sbjct: 243 PLGDRPVVEGKDALRAIAAFRLAMPRTILRYAGGREITLGDLGTRSGLLGGINAVIVGNY 302

Query: 317 LTTLGRPAEADLRLLDDLQMPIKALNASL 345
           LTTLGRPA  DL LLDDL+MP+KAL+A+L
Sbjct: 303 LTTLGRPATTDLELLDDLKMPVKALSATL 331


>sp|A4X585|BIOB_SALTO Tax_Id=369723 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Salinispora tropica]
          Length = 331

 Score =  501 bits (1289), Expect = e-140
 Identities = 242/329 (73%), Positives = 283/329 (86%)

Query: 17  DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISL 76
           +IL QAR QVLE G GL    VL +L LPD+ L   L LAH+VRMRWCGPEVE+EGI+SL
Sbjct: 3   EILDQARTQVLENGVGLDEAGVLAVLNLPDEHLPAALQLAHEVRMRWCGPEVEVEGIVSL 62

Query: 77  KTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERL 136
           KTGGCPEDCHFCSQSGLF SPVR+ WLDI SLVEAAKQTAK+GATEFCIVAAVRGPD+RL
Sbjct: 63  KTGGCPEDCHFCSQSGLFTSPVRAVWLDIPSLVEAAKQTAKTGATEFCIVAAVRGPDDRL 122

Query: 137 MSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTH 196
           M Q+  G+ AI+ EV+I +A S+GMLT EQV++L  +GVHRYNHNLET RS+F NVVTTH
Sbjct: 123 MRQLREGVAAIQAEVDIQVAASVGMLTQEQVDELVEMGVHRYNHNLETCRSYFPNVVTTH 182

Query: 197 TWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGT 256
           +WEERW+TL MVR++GMEVCCGGILG+GE+VEQRAEFA +LAEL P EVPLNFLNPRPGT
Sbjct: 183 SWEERWETLRMVRESGMEVCCGGILGLGESVEQRAEFAAQLAELDPHEVPLNFLNPRPGT 242

Query: 257 PFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNY 316
           P G   V+   +AL+++AAFRLA+PRTILR+AGGRE+TLGDLG + G+LGGINAVIVGNY
Sbjct: 243 PLGDRSVVEGKDALRAIAAFRLAMPRTILRYAGGRELTLGDLGTRSGLLGGINAVIVGNY 302

Query: 317 LTTLGRPAEADLRLLDDLQMPIKALNASL 345
           LTTLGRPA  DL LL+DL+MP+KAL+A+L
Sbjct: 303 LTTLGRPATTDLELLEDLKMPVKALSATL 331


>tr|C4EDN7|C4EDN7_STRRS Tax_Id=479432 SubName: Full=Biotin
           synthetase;[Streptosporangium roseum DSM 43021]
          Length = 332

 Score =  501 bits (1289), Expect = e-140
 Identities = 243/330 (73%), Positives = 284/330 (86%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           +DIL  AR QVLE G GL   QVL+ L LP DRL +LL LAH+VRM+WCGPEVE+EGI+S
Sbjct: 3   SDILGIARTQVLEEGRGLDAAQVLRCLELPRDRLSDLLGLAHEVRMKWCGPEVEVEGIVS 62

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSG F SPVR+AWLDI SLV+AA++TA++GATEFCIVAAVRGPD R
Sbjct: 63  LKTGGCPEDCHFCSQSGQFSSPVRAAWLDIPSLVQAARETAQTGATEFCIVAAVRGPDRR 122

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           LM QV  G++AI+  V+IN+ACSLGMLT  QV++L+G+GVHRYNHNLETARS F  VVTT
Sbjct: 123 LMDQVREGVKAIQEAVDINVACSLGMLTQAQVDELAGMGVHRYNHNLETARSHFEKVVTT 182

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTW+ERW T  MVR+AGME+CCGGI+GMGE++EQRAEFA +L EL PDEVPLNFLNPRPG
Sbjct: 183 HTWQERWDTCLMVREAGMELCCGGIVGMGESLEQRAEFAGQLGELEPDEVPLNFLNPRPG 242

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPF +L ++  SEAL ++AAFRLALPRTILR+AGGRE+TLGDLG + GMLGGINA+IVGN
Sbjct: 243 TPFASLPLLEGSEALTTIAAFRLALPRTILRYAGGRELTLGDLGTRDGMLGGINAIIVGN 302

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGR A  DL LL DL+MPIKAL+ +L
Sbjct: 303 YLTTLGRTAAKDLDLLVDLKMPIKALSDTL 332


>tr|C4LI85|C4LI85_CORK4 Tax_Id=645127 (bioB)SubName: Full=Biotin
           synthase; EC=2.8.1.6;[Corynebacterium kroppenstedtii]
          Length = 354

 Score =  500 bits (1287), Expect = e-139
 Identities = 244/344 (70%), Positives = 296/344 (86%), Gaps = 1/344 (0%)

Query: 2   TQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRM 61
           +Q+ T S     E  DIL  AR++VLERGEGLS+ ++++ + + DDR++ELLALAH+VR+
Sbjct: 12  SQSATSSETASAEQ-DILDLAREKVLERGEGLSQPEIVRAMTISDDRIDELLALAHEVRL 70

Query: 62  RWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGAT 121
           RWCG  VE EGIISLKTGGCPEDCHFC+QSGLF SPVRSAWLDI +LVEAAKQTAK+GAT
Sbjct: 71  RWCGDAVEAEGIISLKTGGCPEDCHFCAQSGLFESPVRSAWLDIPALVEAAKQTAKTGAT 130

Query: 122 EFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHN 181
           EFCIVAAV+GPDERLMSQ+   I AI+ EV+I +A S+G+LT EQVE+L+  GVHRYNHN
Sbjct: 131 EFCIVAAVKGPDERLMSQLEEAIAAIKAEVDIEVAASIGILTKEQVERLAKAGVHRYNHN 190

Query: 182 LETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELG 241
           LETA+S+F +VVTTH+WE+R +T  MVRDAGMEVCCGGI+GMGETVEQRAEFA +LAEL 
Sbjct: 191 LETAKSYFPHVVTTHSWEKRRETCEMVRDAGMEVCCGGIVGMGETVEQRAEFAAQLAELR 250

Query: 242 PDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAK 301
           PDEVP+NFL+PRPGTPF    VM  +EALK++ AFRLALP+TILRFAGGRE+TLGDLGA+
Sbjct: 251 PDEVPMNFLDPRPGTPFANRPVMESNEALKTIGAFRLALPKTILRFAGGRELTLGDLGAE 310

Query: 302 QGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           +G+LGGINA+IVGNYLTTLGRP E D+ +L+ L +PIKALNA++
Sbjct: 311 KGLLGGINAIIVGNYLTTLGRPQETDVDMLNRLHLPIKALNATV 354


>tr|C1WFW1|C1WFW1_9ACTO Tax_Id=479435 SubName: Full=Biotin
           synthetase;[Kribbella flavida DSM 17836]
          Length = 331

 Score =  498 bits (1281), Expect = e-139
 Identities = 241/330 (73%), Positives = 287/330 (86%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           T IL  AR QVLE+G+GLS++Q+ ++L  PDD+L ELLALAH+VR++WCG EVE+EGIIS
Sbjct: 2   TGILDTARTQVLEQGDGLSQEQLAEVLRTPDDQLPELLALAHEVRVKWCGEEVEVEGIIS 61

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSG F SPVRS WL+I  LVEAAK+TAK+GATEFCIVAAVRGPD R
Sbjct: 62  LKTGGCPEDCHFCSQSGQFTSPVRSVWLNIPELVEAAKETAKTGATEFCIVAAVRGPDAR 121

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           LM QV AGIEAI  EV+INIACSLGMLT +QV++L  +GVHRYNHNLE+ARS+F +VVTT
Sbjct: 122 LMEQVKAGIEAITAEVDINIACSLGMLTQDQVDELKAMGVHRYNHNLESARSYFGDVVTT 181

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           H++EERW+T  MV+ +GME+CCGG++GMGET+EQRAE A +LAEL P EVPLNFLNPRPG
Sbjct: 182 HSFEERWETCVMVKQSGMELCCGGLVGMGETLEQRAELAAQLAELEPHEVPLNFLNPRPG 241

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPFG L VM   +AL+++AAFRLA+P+TILR+AGGRE+TLGDLG + G+LGGINAVIVGN
Sbjct: 242 TPFGDLPVMDGKDALRTIAAFRLAMPKTILRYAGGRELTLGDLGTRDGLLGGINAVIVGN 301

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRPA ADL LL DL+MP+K L  +L
Sbjct: 302 YLTTLGRPATADLDLLADLKMPVKELQKTL 331


>tr|C4REH6|C4REH6_9ACTO Tax_Id=219305 SubName: Full=Biotin
           synthase;[Micromonospora sp. ATCC 39149]
          Length = 331

 Score =  497 bits (1280), Expect = e-139
 Identities = 243/329 (73%), Positives = 281/329 (85%)

Query: 17  DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISL 76
           +IL QAR QVLE G GL +  VL +L LPD+ L   L LAH+VRMRWCGPEVE+EGI+SL
Sbjct: 3   EILDQARTQVLESGVGLDQAGVLAVLKLPDEHLPAALQLAHEVRMRWCGPEVEVEGIVSL 62

Query: 77  KTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERL 136
           KTGGCPEDCHFCSQSGLF SPVRS WLDI SLVEAAKQTA +GATEFCIVAAVRGPD RL
Sbjct: 63  KTGGCPEDCHFCSQSGLFASPVRSVWLDIPSLVEAAKQTAATGATEFCIVAAVRGPDARL 122

Query: 137 MSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTH 196
           M Q+  G+ AIR EV+I +A SLGML+ EQV++L  +GVHRYNHNLET RS+F NVVTTH
Sbjct: 123 MKQMREGVAAIRAEVDIQVAASLGMLSQEQVDELVDMGVHRYNHNLETCRSYFPNVVTTH 182

Query: 197 TWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGT 256
           +WEERW+TL MVR++GMEVCCGGILG+GE+VEQRAEFA +LAEL P EVPLNFLNPRPGT
Sbjct: 183 SWEERWETLRMVRESGMEVCCGGILGLGESVEQRAEFAAQLAELDPHEVPLNFLNPRPGT 242

Query: 257 PFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNY 316
           P G   V+   +AL+++AAFRLA+PRTILR+AGGREITLGDLG + G+LGGINAVIVGNY
Sbjct: 243 PLGDRPVVEGKDALRAIAAFRLAMPRTILRYAGGREITLGDLGTRDGLLGGINAVIVGNY 302

Query: 317 LTTLGRPAEADLRLLDDLQMPIKALNASL 345
           LTTLGRPA  DL LL +L+MP+KAL+A+L
Sbjct: 303 LTTLGRPATDDLALLTELKMPVKALSATL 331


>sp|Q2J6H8|BIOB1_FRASC Tax_Id=106370 (bioB1)RecName: Full=Biotin
           synthase 1; EC=2.8.1.6; AltName: Full=Biotin synthetase
           1;[Frankia sp.]
          Length = 358

 Score =  496 bits (1278), Expect = e-138
 Identities = 242/334 (72%), Positives = 286/334 (85%), Gaps = 1/334 (0%)

Query: 12  DTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIE 71
           D +  DIL  AR++VL+ G GL    VL +L LPD+ L +LLALAH+VRMRWCGPEVE+E
Sbjct: 26  DQDGADILTVARREVLDGGRGLDEAGVLAVLRLPDETLTDLLALAHEVRMRWCGPEVEVE 85

Query: 72  GIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRG 131
           GI+SLKTGGCPEDCHFCSQSG F SPVRSAWLD+ SLV+AA+QTA +GATEFCIVAAVRG
Sbjct: 86  GIVSLKTGGCPEDCHFCSQSGKFDSPVRSAWLDVPSLVDAARQTAATGATEFCIVAAVRG 145

Query: 132 PDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTN 191
           PD RLM+QV  G+ AIR  V+IN+ACSLGMLT EQV++L+ +GVHRYNHNLETARS F N
Sbjct: 146 PDARLMAQVREGVAAIRAAVDINVACSLGMLTSEQVDELTAMGVHRYNHNLETARSHFPN 205

Query: 192 VVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLN 251
           VVTTH+WEERW+T  MVR AGME+CCG ILG+GE++EQRAE A +LA L PDEVPLNFLN
Sbjct: 206 VVTTHSWEERWETCEMVRAAGMELCCGAILGVGESLEQRAELATQLAALEPDEVPLNFLN 265

Query: 252 PRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAV 311
           PRPGTPFG L ++ P +AL+++AAFRLA+PRTILR++GGREITLGDL   QGMLGGINA+
Sbjct: 266 PRPGTPFGDLPLVEPRDALRAIAAFRLAMPRTILRYSGGREITLGDLDV-QGMLGGINAM 324

Query: 312 IVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           IVGNYLTTLGR AEADL++L +L MPIK+L A+L
Sbjct: 325 IVGNYLTTLGRSAEADLKMLAELSMPIKSLQATL 358


>sp|A8L2N0|BIOB_FRASN Tax_Id=298653 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Frankia sp.]
          Length = 361

 Score =  495 bits (1274), Expect = e-138
 Identities = 241/329 (73%), Positives = 283/329 (86%), Gaps = 1/329 (0%)

Query: 17  DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISL 76
           DILA+AR+QVL+ G GL    VL +L LPD+ L +LLALAH+VR+RWCGPEVE+EGIISL
Sbjct: 34  DILARARRQVLDEGRGLDEQDVLAVLQLPDEALGDLLALAHEVRLRWCGPEVEVEGIISL 93

Query: 77  KTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERL 136
           KTGGCPEDCHFCSQSG F SPVRSAWLD+ SLVEAAK TA +GATEFCIVAAVRGPD+RL
Sbjct: 94  KTGGCPEDCHFCSQSGRFDSPVRSAWLDVPSLVEAAKATAATGATEFCIVAAVRGPDQRL 153

Query: 137 MSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTH 196
           M+Q+  G+ AIR  V+IN+ACSLGMLT EQV++L+G+GVHRYNHNLETARS F  VVTTH
Sbjct: 154 MAQIREGVAAIREAVDINVACSLGMLTQEQVDELAGLGVHRYNHNLETARSHFPKVVTTH 213

Query: 197 TWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGT 256
           +WEERW+T  +VR AGME+CCG I+G+GE++EQRAE A +LA L PDEVPLNFLNPRPGT
Sbjct: 214 SWEERWETCELVRAAGMELCCGAIIGVGESLEQRAELAAQLAALEPDEVPLNFLNPRPGT 273

Query: 257 PFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNY 316
           PFG L  +   EAL+++AAFRLALPRTILR+AGGREITLGDL   QGMLGGINAVIVGNY
Sbjct: 274 PFGDLPAVDSREALRTIAAFRLALPRTILRYAGGREITLGDLDV-QGMLGGINAVIVGNY 332

Query: 317 LTTLGRPAEADLRLLDDLQMPIKALNASL 345
           LTTLG+  E+DL +L +L+MPIK+L A+L
Sbjct: 333 LTTLGKNPESDLAMLTELRMPIKSLQATL 361


>sp|Q0RD46|BIOB_FRAAA Tax_Id=326424 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Frankia alni]
          Length = 351

 Score =  494 bits (1272), Expect = e-138
 Identities = 244/328 (74%), Positives = 282/328 (85%), Gaps = 1/328 (0%)

Query: 18  ILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISLK 77
           +LA AR++VLE G GL    VL +L LPD+ L + LALAH+VRMRWCGPEVE+EGIISLK
Sbjct: 25  LLAHARREVLEAGRGLDEAGVLAVLRLPDEYLGDALALAHEVRMRWCGPEVEVEGIISLK 84

Query: 78  TGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERLM 137
           TGGCPEDCHFCSQSG F SPVRSAWLD+ SLVEAA+QTA +GATEFCIVAAVRGPD RLM
Sbjct: 85  TGGCPEDCHFCSQSGKFDSPVRSAWLDVPSLVEAARQTAATGATEFCIVAAVRGPDARLM 144

Query: 138 SQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTHT 197
           SQV  G+ AIR  V+IN+ACSLGMLT +QV++L+ IGVHRYNHNLET+RS F  VVTTH+
Sbjct: 145 SQVREGVAAIRAAVDINVACSLGMLTQDQVDELTAIGVHRYNHNLETSRSHFPKVVTTHS 204

Query: 198 WEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGTP 257
           WEERW+T  MVR AGME+CCG ILG+GE++EQRAE A +LA L PDEVPLNFLNPRPGTP
Sbjct: 205 WEERWETCEMVRAAGMELCCGAILGVGESLEQRAELAAQLAVLEPDEVPLNFLNPRPGTP 264

Query: 258 FGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNYL 317
           FG    + P +AL+++AAFRLALPRTILR++GGREITLGDL A QGMLGGINAVIVGNYL
Sbjct: 265 FGDYPPVQPRDALRAIAAFRLALPRTILRYSGGREITLGDLEA-QGMLGGINAVIVGNYL 323

Query: 318 TTLGRPAEADLRLLDDLQMPIKALNASL 345
           TTLGRPAE+DL++L DL MPIK+L A+L
Sbjct: 324 TTLGRPAESDLKMLADLSMPIKSLQATL 351


>sp|B1VF77|BIOB_CORU7 Tax_Id=504474 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Corynebacterium urealyticum]
          Length = 338

 Score =  491 bits (1264), Expect = e-137
 Identities = 239/333 (71%), Positives = 286/333 (85%)

Query: 13  TENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEG 72
           ++   ILA AR+QVL+RGEGLS++QVL++L LPD+++EELLALAH+VR++WCG EVEIEG
Sbjct: 6   SQTPGILATAREQVLQRGEGLSQEQVLEVLNLPDEQIEELLALAHEVRVKWCGEEVEIEG 65

Query: 73  IISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGP 132
           I+SLKTGGCPEDCHFCSQSGLF +PVRS WLDI  LVE AKQTAK+GATEFCIVAAV+GP
Sbjct: 66  IVSLKTGGCPEDCHFCSQSGLFETPVRSVWLDIPLLVEQAKQTAKTGATEFCIVAAVKGP 125

Query: 133 DERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNV 192
           DE LM Q+   +EAIR EV+IN+A S+G+LT EQV++L+ IGVHRYNHNLET+RS F NV
Sbjct: 126 DENLMRQLEVAVEAIRAEVDINVAASVGILTQEQVDRLTAIGVHRYNHNLETSRSNFPNV 185

Query: 193 VTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNP 252
           VTTH+WEER++TL MV+++GMEVCCGGILGMGET EQRAEFA ELA L P EVP+NFL+P
Sbjct: 186 VTTHSWEERYETLKMVKESGMEVCCGGILGMGETREQRAEFAAELASLEPHEVPMNFLDP 245

Query: 253 RPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVI 312
           RPGTPF    VM  SEALK++ AFRLALPRT LRFAGGRE+TL D G + G+LGGIN +I
Sbjct: 246 RPGTPFADYPVMAGSEALKTIGAFRLALPRTTLRFAGGRELTLEDFGTEAGLLGGINGMI 305

Query: 313 VGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           VGNYLTTLGR  EAD+ +L+ L +PIKALN S+
Sbjct: 306 VGNYLTTLGRDQEADVDMLNRLSLPIKALNRSV 338


>sp|Q6NKC7|BIOB1_CORDI Tax_Id=1717 (bioB1)RecName: Full=Biotin
           synthase 1; EC=2.8.1.6; AltName: Full=Biotin synthetase
           1;[Corynebacterium diphtheriae]
          Length = 350

 Score =  491 bits (1264), Expect = e-137
 Identities = 239/338 (70%), Positives = 287/338 (84%)

Query: 8   STNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPE 67
           +T  +   TDIL  AR +VL  GEGL++++VLQ+L L + R+ ELL LAH+VR++WCG E
Sbjct: 13  ATTWEHHVTDILELARTKVLNNGEGLNKEEVLQVLQLDEARIPELLELAHEVRLKWCGEE 72

Query: 68  VEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVA 127
           VE+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLDI  LVEAAKQT KSGATEFCIVA
Sbjct: 73  VEVEGIISLKTGGCPEDCHFCSQSGLFESPVRSAWLDIAGLVEAAKQTQKSGATEFCIVA 132

Query: 128 AVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARS 187
           AV+GPDERLMSQ+   + AI++EV+I +A S+G+LT EQV++L   GVHRYNHNLETARS
Sbjct: 133 AVKGPDERLMSQLEEAVAAIKSEVDIEVAASIGILTQEQVDRLKAAGVHRYNHNLETARS 192

Query: 188 FFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPL 247
           +F NVVTTH+WE R +TL MV +AGMEVC GGI+GMGET+EQRAEFA +LAEL P EVP+
Sbjct: 193 YFPNVVTTHSWESRRETLRMVGEAGMEVCSGGIIGMGETLEQRAEFACDLAELNPTEVPM 252

Query: 248 NFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGG 307
           NFL+PRPGTPF   EV+  ++AL+++ AFRLALP+TILRFAGGRE+TLGDLG +QG+LGG
Sbjct: 253 NFLDPRPGTPFADYEVLDTTDALRAIGAFRLALPKTILRFAGGRELTLGDLGTEQGLLGG 312

Query: 308 INAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           INAVIVGNYLTTLGRP E DL +L  L++PIKALNAS+
Sbjct: 313 INAVIVGNYLTTLGRPMEQDLDMLGKLRLPIKALNASV 350


>tr|C7MZ14|C7MZ14_SACVD Tax_Id=471857 SubName: Full=Biotin
           synthetase; EC=2.8.1.6;[Saccharomonospora viridis]
          Length = 338

 Score =  491 bits (1264), Expect = e-137
 Identities = 240/334 (71%), Positives = 289/334 (86%), Gaps = 1/334 (0%)

Query: 13  TENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEG 72
           T  + ILA AR+QVL++G GLS+ QVL++L L D+ + ELL+LAH+VRM+WCGPEVE+EG
Sbjct: 5   TTESGILAVAREQVLQKGIGLSQQQVLEVLRLGDEHIPELLSLAHEVRMKWCGPEVEVEG 64

Query: 73  IISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGP 132
           I+S+KTGGCPEDCHFCSQSG F +PVRSAWLDI  LV+AA +TA +GATEFCIVAAVRGP
Sbjct: 65  IVSVKTGGCPEDCHFCSQSGRFPTPVRSAWLDIPGLVKAAAETAATGATEFCIVAAVRGP 124

Query: 133 DERLMSQVAAGIEAIRNEV-EINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTN 191
           D RLMSQ+  GI+AIR+   +I IACSLGMLT EQV++L  +GVHRYNHNLETARS F N
Sbjct: 125 DARLMSQIRDGIKAIRDSGNDIQIACSLGMLTQEQVDELVDMGVHRYNHNLETARSHFPN 184

Query: 192 VVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLN 251
           VVTTHTWEERW+TL  VR AGMEVCCGGI+G+GET+EQRAEFA++LAEL P EVP+NFL 
Sbjct: 185 VVTTHTWEERWETLQRVRAAGMEVCCGGIIGIGETLEQRAEFAVQLAELDPHEVPMNFLI 244

Query: 252 PRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAV 311
           P+PGTP+ + +V+   +AL+ VAAFRLA+PRT+LRFAGGRE+TLGDLGA+QGMLGGINA+
Sbjct: 245 PQPGTPYESYDVVEGKDALRVVAAFRLAMPRTMLRFAGGRELTLGDLGAEQGMLGGINAI 304

Query: 312 IVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           IVGNYLT LGRPA  DL +LDDL+MPIKAL+ +L
Sbjct: 305 IVGNYLTNLGRPAAQDLSMLDDLRMPIKALSDTL 338


>sp|Q4JWG3|BIOB_CORJK Tax_Id=306537 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Corynebacterium jeikeium]
          Length = 357

 Score =  487 bits (1253), Expect = e-135
 Identities = 240/342 (70%), Positives = 285/342 (83%)

Query: 4   AGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRW 63
           AGT  T G     +IL  AR +VLE GE L+ ++ LQ+L L D+ L+ELL LAH VR++W
Sbjct: 16  AGTTGTAGTAATPEILNLARTKVLENGEPLNYEETLQVLQLGDEHLDELLDLAHQVRLKW 75

Query: 64  CGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEF 123
           CG  VE+EGIISL+TGGCPEDCHFC+QSGLF SPVRS  LDI  L+EAAKQTAK+GATEF
Sbjct: 76  CGDAVEMEGIISLQTGGCPEDCHFCAQSGLFESPVRSIQLDIAQLIEAAKQTAKTGATEF 135

Query: 124 CIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLE 183
           CIVAAV+GPDE LM+Q+A  I AI+ EV+INIA S+G+LT EQV++L  +GVHRYNHNLE
Sbjct: 136 CIVAAVKGPDEDLMNQMAKAIAAIQAEVDINIAASIGILTQEQVDRLKELGVHRYNHNLE 195

Query: 184 TARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPD 243
           T +S+F  VVTTHTWEER  TL MVRDAGMEVCCGGI+GMGETVEQRAEFA++L  L P 
Sbjct: 196 TCKSYFPEVVTTHTWEERTSTLEMVRDAGMEVCCGGIVGMGETVEQRAEFAIDLQNLDPT 255

Query: 244 EVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQG 303
           EVPLNF +PRPGTPF  LE MP ++AL+++ AFRLALPR +LRFAGGRE+TLGDLGA++G
Sbjct: 256 EVPLNFFDPRPGTPFADLEPMPVNDALRTIGAFRLALPRQLLRFAGGRELTLGDLGAEKG 315

Query: 304 MLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           +LGGINAVIVGNYLTTLGRPAE D+ +L  LQ+PIKALNA+L
Sbjct: 316 LLGGINAVIVGNYLTTLGRPAERDVDMLGKLQLPIKALNATL 357


>tr|C6WDB5|C6WDB5_ACTMD Tax_Id=446462 SubName: Full=Biotin synthase;
           EC=2.8.1.6;[Actinosynnema mirum]
          Length = 347

 Score =  487 bits (1253), Expect = e-135
 Identities = 244/347 (70%), Positives = 287/347 (82%), Gaps = 2/347 (0%)

Query: 1   VTQAGTRSTNGDTENT-DILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDV 59
           ++ A  ++  G TE   D+LA+A ++VLE G GL+ +QV ++L LPD+R+ ELLALAH+V
Sbjct: 1   MSAAPEQTAPGGTEQPGDVLAEAGERVLEGGVGLTEEQVRRVLALPDERIPELLALAHEV 60

Query: 60  RMRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSG 119
           R+RWCGPEVE+EGI+SLKTGGCPEDCHFCSQSG F SPVRSAWLD+  LV AA+QTA +G
Sbjct: 61  RVRWCGPEVEVEGIVSLKTGGCPEDCHFCSQSGRFPSPVRSAWLDVPGLVRAARQTADTG 120

Query: 120 ATEFCIVAAVRGPDERLMSQVAAGIEAIRNEVE-INIACSLGMLTVEQVEQLSGIGVHRY 178
           ATEFC+VAAVRGPD RL++QV AGIEAIR +   I IACSLGMLT EQV++L  +GVHRY
Sbjct: 121 ATEFCVVAAVRGPDARLLAQVRAGIEAIRADGNPIQIACSLGMLTQEQVDELVAMGVHRY 180

Query: 179 NHNLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELA 238
           NHNLETARS F NVVTTH+WEERW TL MVR AGMEVCCGGI+GMGE+  QRAEFA +LA
Sbjct: 181 NHNLETARSHFPNVVTTHSWEERWDTLRMVRAAGMEVCCGGIIGMGESQAQRAEFAAQLA 240

Query: 239 ELGPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDL 298
            L PDEVPLNFL P PGTP+    V+  +EAL+ V AFRLALPRTILRFAGGRE+T GDL
Sbjct: 241 ALEPDEVPLNFLIPNPGTPYEDYPVVEGAEALRVVGAFRLALPRTILRFAGGRELTFGDL 300

Query: 299 GAKQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           GAK+GMLGGINA+IVGNYLT LGRPA  DL +L++L MPIK LN +L
Sbjct: 301 GAKRGMLGGINAIIVGNYLTNLGRPAWEDLDMLEELAMPIKELNRTL 347


>tr|C8RRK5|C8RRK5_CORJE Tax_Id=525262 (bioB)SubName: Full=Biotin
           synthase; EC=2.8.1.6;[Corynebacterium jeikeium ATCC
           43734]
          Length = 345

 Score =  485 bits (1249), Expect = e-135
 Identities = 239/345 (69%), Positives = 286/345 (82%)

Query: 1   VTQAGTRSTNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVR 60
           +T A T+   G     +IL  AR +VLE GE L+ ++ LQ+L L D+ L+ELL LAH VR
Sbjct: 1   MTTAETKQPTGTPATPEILNLARTKVLENGEPLNYEETLQVLQLGDEHLDELLELAHQVR 60

Query: 61  MRWCGPEVEIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGA 120
           ++WCG  VE+EGIISL+TGGCPEDCHFC+QSGLF SPVRS  LDI  L+EAAKQTAK+GA
Sbjct: 61  LKWCGDAVEMEGIISLQTGGCPEDCHFCAQSGLFESPVRSIQLDIAQLIEAAKQTAKTGA 120

Query: 121 TEFCIVAAVRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNH 180
           TEFCIVAAV+GPDE LM+Q+A  I AI+ EV+INIA S+G+LT EQV++L  +GVHRYNH
Sbjct: 121 TEFCIVAAVKGPDEDLMNQMAKAIAAIQAEVDINIAASIGILTQEQVDRLKELGVHRYNH 180

Query: 181 NLETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAEL 240
           NLET +S+F  VVTTHTWEER  TL MVRDAGMEVCCGGI+GMGETVEQRAEFA++L  L
Sbjct: 181 NLETCKSYFPEVVTTHTWEERTSTLEMVRDAGMEVCCGGIVGMGETVEQRAEFAIDLQNL 240

Query: 241 GPDEVPLNFLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGA 300
            P EVPLNF +PRPGTPF  LE MP ++AL+++ AFRLALPR +LRFAGGRE+TLGDLGA
Sbjct: 241 DPTEVPLNFFDPRPGTPFADLEPMPVNDALRTIGAFRLALPRQLLRFAGGRELTLGDLGA 300

Query: 301 KQGMLGGINAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           ++G+LGGINAVIVGNYLTTLGRPAE D+ +L  LQ+PIKALNA+L
Sbjct: 301 EKGLLGGINAVIVGNYLTTLGRPAERDVDMLGKLQLPIKALNATL 345


>tr|C0E1U1|C0E1U1_9CORY Tax_Id=566549 SubName: Full=Putative
           uncharacterized protein;[Corynebacterium matruchotii
           ATCC 33806]
          Length = 376

 Score =  479 bits (1234), Expect = e-133
 Identities = 233/330 (70%), Positives = 278/330 (84%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           TDIL  AR +VL++G GL + + LQ+L L DDR+ E+L LAH VR++WCG E+E EGIIS
Sbjct: 47  TDILELARTKVLDQGIGLDQGETLQVLQLGDDRITEILELAHQVRLKWCGEEIEAEGIIS 106

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVRSAWLDI  LVEAAKQT KSGATEFCIVAAV+GPD+R
Sbjct: 107 LKTGGCPEDCHFCSQSGLFESPVRSAWLDIAGLVEAAKQTQKSGATEFCIVAAVKGPDDR 166

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           LM+Q+   + AI+ EV+I +A S+G+LT EQV++L   GVHRYNHNLETARSFF NVVTT
Sbjct: 167 LMNQLEQAVAAIKAEVDIEVAASVGILTQEQVDRLKAAGVHRYNHNLETARSFFPNVVTT 226

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTWE R +TL MV +AGMEVC GGILGMGE++EQRAEFA +LAEL P EVP+NFL+PRPG
Sbjct: 227 HTWESRRETLRMVAEAGMEVCSGGILGMGESLEQRAEFASDLAELNPTEVPMNFLDPRPG 286

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPF   EVM  ++AL+++ AFRLALP+TILRFAGGRE+TLGDLG +QG+LGGINA+IVGN
Sbjct: 287 TPFADKEVMATTDALRAIGAFRLALPKTILRFAGGRELTLGDLGTEQGLLGGINAMIVGN 346

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRP E DL +LD L++P+K L  S+
Sbjct: 347 YLTTLGRPMENDLDMLDKLRIPLKVLTTSV 376


>tr|C5VAB0|C5VAB0_9CORY Tax_Id=553207 (bioB)SubName: Full=Biotin
           synthase; EC=2.8.1.6;[Corynebacterium matruchotii ATCC
           14266]
          Length = 339

 Score =  476 bits (1224), Expect = e-132
 Identities = 232/330 (70%), Positives = 276/330 (83%)

Query: 16  TDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIIS 75
           TDIL  AR +VL++G GL + + LQ+L L DDR+ E+L LAH VR++WCG E+E EGIIS
Sbjct: 10  TDILELARTKVLDQGIGLDQGETLQVLQLGDDRITEILELAHQVRLKWCGEEIEAEGIIS 69

Query: 76  LKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDER 135
           LKTGGCPEDCHFCSQSGLF SPVRSAWLDI  LVEAAKQT KSGATEFCIVAAV+GPD+R
Sbjct: 70  LKTGGCPEDCHFCSQSGLFESPVRSAWLDIAGLVEAAKQTQKSGATEFCIVAAVKGPDDR 129

Query: 136 LMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTT 195
           LM+Q+   + AI+ EV+I +A S+G+LT EQV++L   GVHRYNHNLETARSFF NVVTT
Sbjct: 130 LMNQLEQAVAAIKAEVDIEVAASVGILTQEQVDRLKAAGVHRYNHNLETARSFFPNVVTT 189

Query: 196 HTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPG 255
           HTWE R  TL MV  AG+EVC GGILGMGE++EQRAEFA +LAEL P EVP+NFL+PRPG
Sbjct: 190 HTWESRRDTLRMVAAAGIEVCSGGILGMGESLEQRAEFASDLAELNPTEVPMNFLDPRPG 249

Query: 256 TPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGN 315
           TPF   EVM  ++AL+++ AFRLALP+TILRFAGGRE+TLGDLG +QG+LGGINA+IVGN
Sbjct: 250 TPFADKEVMATADALRAIGAFRLALPKTILRFAGGRELTLGDLGTEQGLLGGINAMIVGN 309

Query: 316 YLTTLGRPAEADLRLLDDLQMPIKALNASL 345
           YLTTLGRP E DL +LD L++P+K L  S+
Sbjct: 310 YLTTLGRPMENDLDMLDKLRIPLKVLTTSV 339


>sp|P46396|BIOB_CORGL Tax_Id=1718 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Corynebacterium glutamicum]
          Length = 334

 Score =  471 bits (1211), Expect = e-131
 Identities = 225/325 (69%), Positives = 277/325 (85%)

Query: 18  ILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISLK 77
           IL  AR QVLE+G GL++ Q++++L LP++++ +L+ LAH VR++WCG E+E+EGIISLK
Sbjct: 7   ILDTARTQVLEQGIGLNQQQLMEVLTLPEEQIPDLMELAHQVRLKWCGEEIEVEGIISLK 66

Query: 78  TGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERLM 137
           TGGCPEDCHFCSQSGLF SPVRS WLDI +LVEAAKQTAK+GATEFCIVAAV+GPDERLM
Sbjct: 67  TGGCPEDCHFCSQSGLFESPVRSVWLDIPNLVEAAKQTAKTGATEFCIVAAVKGPDERLM 126

Query: 138 SQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTHT 197
           +Q+   + AI +EVEI +A S+G L  EQV++L+  GVHRYNHNLETARS+F  VVTTHT
Sbjct: 127 TQLEEAVLAIHSEVEIEVAASIGTLNKEQVDRLAAAGVHRYNHNLETARSYFPEVVTTHT 186

Query: 198 WEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGTP 257
           WEER +TL +V +AGMEVC GGILGMGET+EQRAEFA++LAEL P EVP+NFL+PRPGTP
Sbjct: 187 WEERRETLRLVAEAGMEVCSGGILGMGETLEQRAEFAVQLAELDPHEVPMNFLDPRPGTP 246

Query: 258 FGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNYL 317
           F   E+M   +AL+S+ AFRLA+P T+LRFAGGRE+TLGD G++Q +LGGINA+IVGNYL
Sbjct: 247 FADRELMDSRDALRSIGAFRLAMPHTMLRFAGGRELTLGDKGSEQALLGGINAMIVGNYL 306

Query: 318 TTLGRPAEADLRLLDDLQMPIKALN 342
           TTLGRP E DL ++D LQ+PIK LN
Sbjct: 307 TTLGRPMEDDLDMMDRLQLPIKVLN 331


>sp|A4QA10|BIOB_CORGB Tax_Id=340322 (bioB)RecName: Full=Biotin
           synthase; EC=2.8.1.6; AltName: Full=Biotin
           synthetase;[Corynebacterium glutamicum]
          Length = 334

 Score =  471 bits (1211), Expect = e-131
 Identities = 225/325 (69%), Positives = 277/325 (85%)

Query: 18  ILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEVEIEGIISLK 77
           IL  AR QVLE+G GL++ Q++++L LP++++ +L+ LAH VR++WCG E+E+EGIISLK
Sbjct: 7   ILDTARTQVLEQGIGLNQQQLMEVLTLPEEQIPDLMELAHQVRLKWCGEEIEVEGIISLK 66

Query: 78  TGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAAVRGPDERLM 137
           TGGCPEDCHFCSQSGLF SPVRS WLDI +LVEAAKQTAK+GATEFCIVAAV+GPDERLM
Sbjct: 67  TGGCPEDCHFCSQSGLFESPVRSVWLDIPNLVEAAKQTAKTGATEFCIVAAVKGPDERLM 126

Query: 138 SQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSFFTNVVTTHT 197
           +Q+   + AI +EVEI +A S+G L  EQV++L+  GVHRYNHNLETARS+F  VVTTHT
Sbjct: 127 TQLEEAVLAIHSEVEIEVAASIGTLNKEQVDRLAAAGVHRYNHNLETARSYFPEVVTTHT 186

Query: 198 WEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLNFLNPRPGTP 257
           WEER +TL +V +AGMEVC GGILGMGET+EQRAEFA++LAEL P EVP+NFL+PRPGTP
Sbjct: 187 WEERRETLRLVAEAGMEVCSGGILGMGETLEQRAEFAVQLAELDPHEVPMNFLDPRPGTP 246

Query: 258 FGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGINAVIVGNYL 317
           F   E+M   +AL+S+ AFRLA+P T+LRFAGGRE+TLGD G++Q +LGGINA+IVGNYL
Sbjct: 247 FADRELMDSRDALRSIGAFRLAMPHTMLRFAGGRELTLGDKGSEQALLGGINAMIVGNYL 306

Query: 318 TTLGRPAEADLRLLDDLQMPIKALN 342
           TTLGRP E DL ++D LQ+PIK LN
Sbjct: 307 TTLGRPMEDDLDMMDRLQLPIKVLN 331


  Database: Amellifera_nr
    Posted date:  Jan 15, 2010  5:10 AM
  Number of letters in database: 3,808,957,724
  Number of sequences in database:  11,153,314
  
Lambda     K      H
   0.319    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11153314
Number of Hits to DB: 2,499,296,743
Number of extensions: 102345802
Number of successful extensions: 264168
Number of sequences better than 10.0: 1797
Number of HSP's gapped: 262089
Number of HSP's successfully gapped: 1797
Length of query: 345
Length of database: 3,808,957,724
Length adjustment: 138
Effective length of query: 207
Effective length of database: 2,269,800,392
Effective search space: 469848681144
Effective search space used: 469848681144
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 81 (35.8 bits)