BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ML1752c
         (302 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,153,314 sequences; 3,808,957,724 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|Q9CBP4|Q9CBP4_MYCLE Tax_Id=1769 SubName: Full=Putative unchar...   602   e-170
tr|B8ZS54|B8ZS54_MYCLB Tax_Id=561304 SubName: Full=Putative unch...   602   e-170
sp|P64830|Y1392_MYCBO Tax_Id=1765 RecName: Full=Uncharacterized ...   377   e-103
sp|P64829|Y1357_MYCTU Tax_Id=1773 RecName: Full=Uncharacterized ...   377   e-103
tr|C6DTM8|C6DTM8_MYCTK Tax_Id=478434 SubName: Full=Putative unch...   377   e-103
tr|A5U257|A5U257_MYCTA Tax_Id=419947 SubName: Full=Putative unch...   377   e-103
tr|A5WM41|A5WM41_MYCTF Tax_Id=336982 SubName: Full=Putative unch...   377   e-103
tr|A4KGS3|A4KGS3_MYCTU Tax_Id=395095 SubName: Full=Putative unch...   377   e-103
tr|A2VHP5|A2VHP5_MYCTU Tax_Id=348776 SubName: Full=Putative unch...   377   e-103
tr|C1AN02|C1AN02_MYCBT Tax_Id=561275 SubName: Full=Putative unch...   376   e-102
tr|A1KIE7|A1KIE7_MYCBP Tax_Id=410289 SubName: Full=Putative unch...   376   e-102
tr|A4X9X5|A4X9X5_SALTO Tax_Id=369723 SubName: Full=Diguanylate c...   246   2e-63
tr|C6WQX4|C6WQX4_ACTMD Tax_Id=446462 SubName: Full=Diguanylate c...   243   2e-62
tr|A8LYA7|A8LYA7_SALAI Tax_Id=391037 SubName: Full=Diguanylate c...   240   1e-61
tr|C4RLN6|C4RLN6_9ACTO Tax_Id=219305 SubName: Full=Diguanylate c...   236   3e-60
tr|B5HHX3|B5HHX3_STRPR Tax_Id=457429 SubName: Full=Sensory box/G...   233   2e-59
tr|A4FQH0|A4FQH0_SACEN Tax_Id=405948 SubName: Full=Diguanylate c...   231   6e-59
tr|C8XHN3|C8XHN3_NAKMY Tax_Id=479431 SubName: Full=Diguanylate c...   227   1e-57
tr|B5HNL2|B5HNL2_9ACTO Tax_Id=463191 SubName: Full=Sensory box/G...   226   3e-57
tr|Q82CV1|Q82CV1_STRAW Tax_Id=33903 SubName: Full=Putative senso...   221   8e-56
tr|A4X4M8|A4X4M8_SALTO Tax_Id=369723 SubName: Full=Diguanylate c...   218   9e-55
tr|B4VGA3|B4VGA3_9ACTO Tax_Id=465541 SubName: Full=Sensory box/G...   217   1e-54
tr|A8M737|A8M737_SALAI Tax_Id=391037 SubName: Full=Diguanylate c...   215   4e-54
tr|C4RCD7|C4RCD7_9ACTO Tax_Id=219305 SubName: Full=Diguanylate c...   213   2e-53
tr|B1VW35|B1VW35_STRGG Tax_Id=455632 SubName: Full=Putative unch...   211   1e-52
tr|Q93J80|Q93J80_STRCO Tax_Id=1902 SubName: Full=Putative unchar...   209   2e-52
tr|C9Z2R5|C9Z2R5_STRSW Tax_Id=680198 SubName: Full=Putative digu...   209   3e-52
tr|C9NAM3|C9NAM3_9ACTO Tax_Id=591167 SubName: Full=Diguanylate c...   208   5e-52
tr|Q2JEA5|Q2JEA5_FRASC Tax_Id=106370 SubName: Full=Diguanylate c...   207   1e-51
tr|A1ASF8|A1ASF8_PELPD Tax_Id=338966 SubName: Full=Diguanylate c...   207   2e-51
tr|A8LHD9|A8LHD9_FRASN Tax_Id=298653 SubName: Full=Diguanylate c...   206   2e-51
tr|C7PY35|C7PY35_CATAD Tax_Id=479433 SubName: Full=Diguanylate c...   206   2e-51
tr|B5GAU1|B5GAU1_9ACTO Tax_Id=465543 SubName: Full=Putative unch...   206   3e-51
tr|B4V5X3|B4V5X3_9ACTO Tax_Id=465541 SubName: Full=Putative unch...   206   3e-51
tr|B5HHK8|B5HHK8_STRPR Tax_Id=457429 SubName: Full=Putative unch...   201   9e-50
tr|Q3K7G5|Q3K7G5_PSEPF Tax_Id=205922 SubName: Full=Conserved GGD...   200   2e-49
tr|C9Z514|C9Z514_STRSW Tax_Id=680198 SubName: Full=Putative unch...   200   2e-49
tr|Q3A628|Q3A628_PELCD Tax_Id=338963 SubName: Full=Diguanylate c...   197   1e-48
tr|Q1AVS2|Q1AVS2_RUBXD Tax_Id=266117 SubName: Full=Diguanylate c...   197   1e-48
tr|B7GKP9|B7GKP9_ANOFW Tax_Id=491915 SubName: Full=Multidomain s...   197   1e-48
tr|C9NJG7|C9NJG7_9ACTO Tax_Id=591167 SubName: Full=Diguanylate c...   197   1e-48
tr|C0U555|C0U555_9ACTO Tax_Id=526225 SubName: Full=PAS domain S-...   196   3e-48
tr|Q1ASD1|Q1ASD1_RUBXD Tax_Id=266117 SubName: Full=Diguanylate c...   196   4e-48
tr|B8DSE5|B8DSE5_DESVM Tax_Id=883 SubName: Full=Diguanylate cycl...   196   4e-48
tr|Q3SJL3|Q3SJL3_THIDA Tax_Id=292415 SubName: Full=Putative digu...   195   6e-48
tr|Q9RCY2|Q9RCY2_STRCO Tax_Id=1902 SubName: Full=Putative unchar...   194   8e-48
tr|B8GNC0|B8GNC0_THISH Tax_Id=396588 SubName: Full=Signal transd...   194   8e-48
tr|Q39XK0|Q39XK0_GEOMG Tax_Id=269799 SubName: Full=Diguanylate c...   194   1e-47
tr|A1K2X7|A1K2X7_AZOSB Tax_Id=62928 (morA)SubName: Full=GGDEF/EA...   194   1e-47
tr|A0ADW3|A0ADW3_STRAM Tax_Id=278992 SubName: Full=Putative unch...   194   1e-47

>tr|Q9CBP4|Q9CBP4_MYCLE Tax_Id=1769 SubName: Full=Putative
           uncharacterized protein ML1752;[Mycobacterium leprae]
          Length = 302

 Score =  602 bits (1552), Expect = e-170
 Identities = 301/302 (99%), Positives = 302/302 (100%)

Query: 1   LPIEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQVIPAAL 60
           +PIEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQVIPAAL
Sbjct: 1   MPIEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQVIPAAL 60

Query: 61  DRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVI 120
           DRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVI
Sbjct: 61  DRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVI 120

Query: 121 EQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTEN 180
           EQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTEN
Sbjct: 121 EQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTEN 180

Query: 181 ASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDI 240
           ASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDI
Sbjct: 181 ASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDI 240

Query: 241 RGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFF 300
           RGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFF
Sbjct: 241 RGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFF 300

Query: 301 TE 302
           TE
Sbjct: 301 TE 302


>tr|B8ZS54|B8ZS54_MYCLB Tax_Id=561304 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium leprae]
          Length = 302

 Score =  602 bits (1552), Expect = e-170
 Identities = 301/302 (99%), Positives = 302/302 (100%)

Query: 1   LPIEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQVIPAAL 60
           +PIEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQVIPAAL
Sbjct: 1   MPIEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQVIPAAL 60

Query: 61  DRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVI 120
           DRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVI
Sbjct: 61  DRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVI 120

Query: 121 EQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTEN 180
           EQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTEN
Sbjct: 121 EQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTEN 180

Query: 181 ASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDI 240
           ASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDI
Sbjct: 181 ASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDI 240

Query: 241 RGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFF 300
           RGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFF
Sbjct: 241 RGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFF 300

Query: 301 TE 302
           TE
Sbjct: 301 TE 302


>sp|P64830|Y1392_MYCBO Tax_Id=1765 RecName: Full=Uncharacterized
           protein Mb1392c;[Mycobacterium bovis]
          Length = 307

 Score =  377 bits (969), Expect = e-103
 Identities = 193/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VETP QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>sp|P64829|Y1357_MYCTU Tax_Id=1773 RecName: Full=Uncharacterized
           protein Rv1357c/MT1400;[Mycobacterium tuberculosis]
          Length = 307

 Score =  377 bits (969), Expect = e-103
 Identities = 193/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VETP QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>tr|C6DTM8|C6DTM8_MYCTK Tax_Id=478434 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium tuberculosis]
          Length = 307

 Score =  377 bits (969), Expect = e-103
 Identities = 193/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VETP QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>tr|A5U257|A5U257_MYCTA Tax_Id=419947 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium tuberculosis]
          Length = 307

 Score =  377 bits (969), Expect = e-103
 Identities = 193/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VETP QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>tr|A5WM41|A5WM41_MYCTF Tax_Id=336982 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium tuberculosis]
          Length = 307

 Score =  377 bits (969), Expect = e-103
 Identities = 193/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VETP QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>tr|A4KGS3|A4KGS3_MYCTU Tax_Id=395095 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium tuberculosis str.
           Haarlem]
          Length = 307

 Score =  377 bits (969), Expect = e-103
 Identities = 193/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VETP QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>tr|A2VHP5|A2VHP5_MYCTU Tax_Id=348776 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium tuberculosis C]
          Length = 307

 Score =  377 bits (969), Expect = e-103
 Identities = 193/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VETP QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVETPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>tr|C1AN02|C1AN02_MYCBT Tax_Id=561275 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium bovis]
          Length = 307

 Score =  376 bits (965), Expect = e-102
 Identities = 192/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VE+P QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVESPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>tr|A1KIE7|A1KIE7_MYCBP Tax_Id=410289 SubName: Full=Putative
           uncharacterized protein BCG_1419c;[Mycobacterium bovis]
          Length = 307

 Score =  376 bits (965), Expect = e-102
 Identities = 192/261 (73%), Positives = 213/261 (81%)

Query: 42  DREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPAR 101
           DR+Q +    L   +  ALDRGEFFLVYQPI+RL D R IG EALLRW HPTLGTLLP R
Sbjct: 47  DRDQVNTRHYLSTSMRVALDRGEFFLVYQPIIRLADNRIIGAEALLRWEHPTLGTLLPGR 106

Query: 102 FISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVER 161
           FI  AE NG++VPLT FV+EQACRH+R+WRD ST+P+PFVSVNVSA  I DP FL +VE 
Sbjct: 107 FIDRAENNGLMVPLTAFVLEQACRHVRSWRDHSTDPQPFVSVNVSASTICDPGFLVLVEG 166

Query: 162 VLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNL 221
           VLGETGLPAHAL+LEL E+A LS DE ++TRLQELSALGVGIAIDDFG GFSSLAYL  L
Sbjct: 167 VLGETGLPAHALQLELAEDARLSRDEKAVTRLQELSALGVGIAIDDFGIGFSSLAYLPRL 226

Query: 222 PVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           PVD+VKL G+FIE L GDI+ RLA+EQITRAMIDL  KLGI V AK VE+P QAARLR F
Sbjct: 227 PVDVVKLGGKFIECLDGDIQARLANEQITRAMIDLGDKLGITVTAKLVESPSQAARLRAF 286

Query: 282 GCDAAQGWHFAKALPADFFTE 302
           GC AAQGWHFAKALP DFF E
Sbjct: 287 GCKAAQGWHFAKALPVDFFRE 307


>tr|A4X9X5|A4X9X5_SALTO Tax_Id=369723 SubName: Full=Diguanylate
           cyclase/phosphodiesterase;[Salinispora tropica]
          Length = 585

 Score =  246 bits (629), Expect = 2e-63
 Identities = 135/284 (47%), Positives = 178/284 (62%), Gaps = 12/284 (4%)

Query: 16  CSDRSADSRGSGEVKDRSSGWFYGHHDREQRSV-HDGLLQVIPAALDRGEFFLVYQPIVR 74
           C+   A + G G+       W     +R++R +    L   IPA LDRGEF+L YQP+  
Sbjct: 306 CTLHWAKAAGGGQ-------WMLYDAERDRRELTRQALTAAIPAGLDRGEFYLDYQPLTS 358

Query: 75  LNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDS 134
           L D R +GVEAL+RW HP LG L P RFI LAE  G+IVPL  +V+ +ACR   +W    
Sbjct: 359 LRDGRLLGVEALVRWRHPELGVLRPGRFIGLAEETGLIVPLGGWVLAEACRTAGSW--SV 416

Query: 135 TNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQ 194
           T   PFVSVN++ R +  P  +  V  +L  TGLP   L+LE+TE+A +S  +  +  L+
Sbjct: 417 TGGTPFVSVNLAVRQVHRPGLVQEVRTLLRHTGLPPERLQLEITESAMMSPADEPVRALR 476

Query: 195 ELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMI 254
            L+ LGV IAIDDFGTG+S+LAYLR+LPV  +K+AGEF+  L    +   ADE+I  +++
Sbjct: 477 HLADLGVRIAIDDFGTGYSNLAYLRDLPVTELKVAGEFVAGL--RTQEPQADERIVASLV 534

Query: 255 DLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPAD 298
            LA  L + V A+ VET GQA RLR  GCDAAQGWHF +  PAD
Sbjct: 535 SLAHALDLTVTAEGVETAGQAERLRAIGCDAAQGWHFGRPEPAD 578


>tr|C6WQX4|C6WQX4_ACTMD Tax_Id=446462 SubName: Full=Diguanylate
           cyclase/phosphodiesterase with PAS/PAC
           sensor(S);[Actinosynnema mirum]
          Length = 720

 Score =  243 bits (621), Expect = 2e-62
 Identities = 134/301 (44%), Positives = 179/301 (59%), Gaps = 3/301 (0%)

Query: 3   IEGAMRSSSLPDGCSDRSADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQV-IPAALD 61
           +E  +  +S PD   D  AD        D  S W     DR  + +    L   +PAAL+
Sbjct: 418 VERGLEGTSAPDLVRD--ADITLYWAKADGKSRWALYDPDRNAKEIARFTLSATMPAALE 475

Query: 62  RGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIE 121
           R EF++ YQP+VRL + R +GVEAL+RW HP  G L P RFI LAE  G+IVPL  +V+ 
Sbjct: 476 RDEFYVDYQPLVRLENARVVGVEALVRWQHPEFGRLAPDRFIELAEETGLIVPLGRWVLR 535

Query: 122 QACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENA 181
           +AC   R W D+     P+VSVN++ R  RDP  +  V+R+L ETGLP   L+LELTE+A
Sbjct: 536 KACEQGRRWLDEFAELAPYVSVNLAVRQSRDPELVRDVKRILDETGLPPRHLQLELTESA 595

Query: 182 SLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIR 241
            +   +  +  L+ LS +GV IAIDDFGTG+S+LAYL++LPV  +K+AG F+E L     
Sbjct: 596 IMGTADEPLEALRALSDMGVRIAIDDFGTGYSNLAYLKHLPVHELKIAGSFMEGLRAADE 655

Query: 242 GRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFFT 301
               D QI   ++ LA  LG+ V A+ VETP QA RL   GCD  QGW +AK +  +   
Sbjct: 656 EDPVDAQIVSTLVQLAHALGLGVTAEGVETPSQAKRLHRIGCDTGQGWFYAKPMAPEGID 715

Query: 302 E 302
           E
Sbjct: 716 E 716


>tr|A8LYA7|A8LYA7_SALAI Tax_Id=391037 SubName: Full=Diguanylate
           cyclase/phosphodiesterase;[Salinispora arenicola]
          Length = 594

 Score =  240 bits (613), Expect = 1e-61
 Identities = 129/264 (48%), Positives = 168/264 (63%), Gaps = 5/264 (1%)

Query: 36  WFYGHHDREQRSV-HDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTL 94
           W     +R++R +    L   IP  LDRGEF+L YQP+  L D R +GVEAL+RW HP L
Sbjct: 328 WMIYDPERDRRELTRQALTAAIPTGLDRGEFYLDYQPLTSLRDGRLLGVEALVRWRHPEL 387

Query: 95  GTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPS 154
           G L P +FI LAE  G+IVPL  +V+ +ACR   +W    T   PFVSVN++ R +  P 
Sbjct: 388 GVLRPDQFIGLAEETGLIVPLGGWVLAEACRVAGSW--SGTGGEPFVSVNLAVRQVHRPG 445

Query: 155 FLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSS 214
            +  V  +L  TGLP   L+LE+TE+A +S  E  +  L+ L+ LGV IAIDDFGTG+S+
Sbjct: 446 LVRDVRDLLRHTGLPPERLQLEITESAMMSPAEEPVRALRMLADLGVRIAIDDFGTGYSN 505

Query: 215 LAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQ 274
           LAYLR+LPV  +K+AGEF+  L        ADE+I  +++ LA  L + V A+ VET GQ
Sbjct: 506 LAYLRDLPVTELKVAGEFVAGLRAS--EPQADERILASLVSLAHALNLTVTAEGVETAGQ 563

Query: 275 AARLRDFGCDAAQGWHFAKALPAD 298
           A RLR  GCDA QGWHF +  PAD
Sbjct: 564 AERLRAIGCDAGQGWHFGRPEPAD 587


>tr|C4RLN6|C4RLN6_9ACTO Tax_Id=219305 SubName: Full=Diguanylate
           cyclase/phosphodiesterase;[Micromonospora sp. ATCC
           39149]
          Length = 611

 Score =  236 bits (601), Expect = 3e-60
 Identities = 129/265 (48%), Positives = 165/265 (62%), Gaps = 4/265 (1%)

Query: 36  WFYGHHDREQRSV-HDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTL 94
           W     DR +R +    L   IPAAL+RGEF L YQP+  L D R +GVEAL+RW HP L
Sbjct: 340 WTLFDADRNRRELARYALSAAIPAALERGEFQLDYQPLTSLRDGRVLGVEALVRWRHPEL 399

Query: 95  GTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPS 154
           G L P  FI LAE  G+IVPL ++V+ +ACR    W    T   PFVSVN++ R +  P 
Sbjct: 400 GKLYPGSFIELAEETGLIVPLGSWVLAEACREAATWSSFGT-AAPFVSVNLAVRQVHRPG 458

Query: 155 FLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSS 214
            +  V  VL  TGLP   L+LE+TE+  +S  E  +  L+ L+ +G+ IAIDDFGTG+ +
Sbjct: 459 LVREVRDVLERTGLPPERLQLEVTESTMMSAVEEPVRALRVLADMGMRIAIDDFGTGYCN 518

Query: 215 LAYLRNLPVDMVKLAGEFIENL--GGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETP 272
           LAYLR+LPV  +K+AGEF+  L    D      DE+I  +++ LA  L + V A+ VET 
Sbjct: 519 LAYLRDLPVTELKVAGEFVAGLRAPADDPASRTDERILASLVSLAHALDLTVTAEGVETE 578

Query: 273 GQAARLRDFGCDAAQGWHFAKALPA 297
           GQA RLR  GCDAAQGWHF K  PA
Sbjct: 579 GQADRLRTIGCDAAQGWHFGKPAPA 603


>tr|B5HHX3|B5HHX3_STRPR Tax_Id=457429 SubName: Full=Sensory
           box/GGDEF family protein;[Streptomyces pristinaespiralis
           ATCC 25486]
          Length = 610

 Score =  233 bits (595), Expect = 2e-59
 Identities = 128/286 (44%), Positives = 176/286 (61%), Gaps = 2/286 (0%)

Query: 19  RSADSRGSGEVKDRSSGWFYGHHDRE-QRSVHDGLLQVIPAALDRGEFFLVYQPIVRLND 77
           ++AD+      +D  S W     +R   R     L  ++  A++RGEF L YQP+V + D
Sbjct: 310 QAADTTLYWAKEDGKSRWTLFDPERNAHRMTRQALSSMLRPAVERGEFTLEYQPLVGMAD 369

Query: 78  KRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNP 137
               GVEAL+RW HP  GTL P RF+++AE +G IV L  +V+  ACR  R W+ D  + 
Sbjct: 370 GVTRGVEALVRWNHPQFGTLTPNRFVAIAEEDGSIVQLGQWVLRTACRQARQWQLDHPDV 429

Query: 138 RP-FVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQEL 196
            P FVSVNV+ R + D   ++ V  +L ETGLPAH L+LELTE+A +      +  LQ L
Sbjct: 430 PPLFVSVNVAVRQVWDSDLVADVAEILAETGLPAHLLQLELTESAVMGSAGRPLQALQAL 489

Query: 197 SALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDL 256
           S +GV IAIDDFGTG+S+LAYL  LPV ++KL G F+     +     ADE I +A+++L
Sbjct: 490 SDMGVHIAIDDFGTGYSNLAYLSRLPVSVLKLDGTFVRGFQDEAHANPADETIVQALVEL 549

Query: 257 AFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFFTE 302
           A +LG+ V A+ VET GQA+RLR  GCD  QGW +++A+  D   E
Sbjct: 550 AHRLGLTVTAECVETSGQASRLRRIGCDTGQGWLYSRAVGPDRIAE 595


>tr|A4FQH0|A4FQH0_SACEN Tax_Id=405948 SubName: Full=Diguanylate
           cyclase/phosphodiesterase (GGDEF & EAL domains) with
           PAS/PAC sensor(S);[Saccharopolyspora erythraea]
          Length = 687

 Score =  231 bits (590), Expect = 6e-59
 Identities = 119/238 (50%), Positives = 159/238 (66%)

Query: 56  IPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPL 115
           +PAALD  EF++ YQP++ L D   +GVEAL+RW HP LG L P RFI LAE  G+IVPL
Sbjct: 434 MPAALDSEEFYVEYQPLIGLRDFGVVGVEALVRWWHPELGRLGPDRFIGLAEETGLIVPL 493

Query: 116 TTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRL 175
             +V+ QACR  R W+D+  +  PFVSVN++ R  RDP+ +  V  +L ETGL    L+L
Sbjct: 494 GRWVLRQACRQARQWQDEFGDAAPFVSVNLAVRQSRDPNLVDDVAAILRETGLEPSRLQL 553

Query: 176 ELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIEN 235
           ELTE+A +   +  +  L+ LS +GV IAIDDFGTG+S+LAYLR+LPV  +K+AG F+E 
Sbjct: 554 ELTESAIMGTADEPLDALRALSRMGVRIAIDDFGTGYSNLAYLRHLPVHELKIAGSFMEG 613

Query: 236 LGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAK 293
           L    R    D +I   ++DLA  LG+ V A+ VET  QA R+ D GC+  QG+ FA+
Sbjct: 614 LRDAERADPVDARIVGTLVDLAHALGLTVTAEGVETHAQARRVADIGCETGQGYFFAR 671


>tr|C8XHN3|C8XHN3_NAKMY Tax_Id=479431 SubName: Full=Diguanylate
           cyclase/phosphodiesterase with PAS/PAC
           sensor(S);[Nakamurella multipartita]
          Length = 702

 Score =  227 bits (578), Expect = 1e-57
 Identities = 126/264 (47%), Positives = 164/264 (62%), Gaps = 3/264 (1%)

Query: 36  WFYGHHDREQRSVHD-GLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTL 94
           W     +R  R V    L Q++P ALDRGEF L YQP++ L D RF G EALLRW HP L
Sbjct: 428 WAIFDPERSLREVDQYTLAQLLPTALDRGEFRLHYQPLIALADGRFTGFEALLRWEHPRL 487

Query: 95  GTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPS 154
           G L P RFI+ AE +G+IVP+  +V++++CR  R W  + T  RP VSVNV+ R + D  
Sbjct: 488 GRLRPDRFIAAAEESGIIVPIGQWVLQESCRQARRWY-EITGIRPCVSVNVALRQLSDGG 546

Query: 155 FLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSS 214
            L  V RV+    L    L+LELTE A +  D   +  LQ L+ALGVGIAIDDFGTG+S+
Sbjct: 547 LLDDVLRVIEAEQLTPDQLQLELTERAVIGSDHEPLAELQALAALGVGIAIDDFGTGYSN 606

Query: 215 LAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQ 274
           + YLR LP+  +KL   F+  L  D   +  D +I R+++ LA  LG+ V A+ VET  Q
Sbjct: 607 MTYLRRLPITALKLDQSFVSELRPDAADQ-TDAKIVRSILTLAHDLGLTVTAEGVETAAQ 665

Query: 275 AARLRDFGCDAAQGWHFAKALPAD 298
           A  LR+ GCD AQG +F   +PAD
Sbjct: 666 ARALRELGCDQAQGMYFGAPVPAD 689


>tr|B5HNL2|B5HNL2_9ACTO Tax_Id=463191 SubName: Full=Sensory
           box/GGDEF family protein;[Streptomyces sviceus ATCC
           29083]
          Length = 631

 Score =  226 bits (575), Expect = 3e-57
 Identities = 122/257 (47%), Positives = 158/257 (61%), Gaps = 4/257 (1%)

Query: 46  RSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISL 105
           R     L   +  A++RGEF L YQP+V + D R  GVEAL+RW HP  G L P RFI L
Sbjct: 365 RMTRQALASTLRPAIERGEFRLEYQPLVCMEDGRLRGVEALIRWDHPQFGMLTPNRFIQL 424

Query: 106 AERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRP-FVSVNVSARNIRDPSFLSMVERVLG 164
           AE +G IVPL  +++  ACR  R W+ D  +  P FVSVNV+ R + D   ++ V   L 
Sbjct: 425 AEEDGSIVPLGRWILATACRQARQWQLDHPDEPPIFVSVNVAVRQVWDSDLVADVAETLA 484

Query: 165 ETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVD 224
           ETGL  H L+LELTE+A +      +  LQ LS +GVGIAIDDFGTG+S+LAYL  LPV 
Sbjct: 485 ETGLAPHLLQLELTESAVMGSAGRPLQALQALSDMGVGIAIDDFGTGYSNLAYLSRLPVS 544

Query: 225 MVKLAGEFIENL---GGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDF 281
           ++KL G F+      G  +    ADE +  AMI LA +LG+ V A+ VET  QA+RLR  
Sbjct: 545 VLKLDGSFVRGFQYEGEGVPPNPADEVVVEAMIQLAHRLGLTVTAECVETSAQASRLRRI 604

Query: 282 GCDAAQGWHFAKALPAD 298
           GCD  QGW +++ +  D
Sbjct: 605 GCDTGQGWLYSRPVSPD 621


>tr|Q82CV1|Q82CV1_STRAW Tax_Id=33903 SubName: Full=Putative sensory
           box/GGDEF family protein;[Streptomyces avermitilis]
          Length = 620

 Score =  221 bits (563), Expect = 8e-56
 Identities = 126/283 (44%), Positives = 164/283 (57%), Gaps = 11/283 (3%)

Query: 31  DRSSGWFYGHHDRE-QRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRW 89
           D  S W     +R   R     L   +  A++ GEF L YQP+V + D R  GVEAL+RW
Sbjct: 324 DGKSRWTLFDPERNAHRMTRQALSSGLRPAIEHGEFVLEYQPLVGMEDGRLRGVEALVRW 383

Query: 90  AHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRP-FVSVNVSAR 148
            HP  G L P RFI LAE +G IV L  +V+  ACR  R W+ +  +  P FVSVNV+ R
Sbjct: 384 NHPQFGMLTPNRFIGLAEEDGSIVQLGRWVLATACRQARRWQLEHPDAPPLFVSVNVAVR 443

Query: 149 NIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDF 208
            + D   ++ V  +L ETGL  H L+LELTE+A +      +  LQ LS +GV IAIDDF
Sbjct: 444 QVWDSDLVTDVAEILAETGLAPHLLQLELTESAVMGSAGRPLQALQALSDMGVHIAIDDF 503

Query: 209 GTGFSSLAYLRNLPVDMVKLAGEFIENL---------GGDIRGRLADEQITRAMIDLAFK 259
           GTG+S+LAYL  LPV ++KL G F+            G D R   ADE +  AMI LA +
Sbjct: 504 GTGYSNLAYLSRLPVSVLKLDGSFVRGFQYDTSEKHDGTDARPNPADEVVVEAMIQLAHR 563

Query: 260 LGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFFTE 302
           LG+ V A+ VET  QA+RLR  GCD  QGW +++ +  D  +E
Sbjct: 564 LGLTVTAECVETSAQASRLRGIGCDTGQGWLYSRPVAPDRISE 606


>tr|A4X4M8|A4X4M8_SALTO Tax_Id=369723 SubName: Full=Diguanylate
           cyclase/phosphodiesterase with PAS/PAC
           sensor(S);[Salinispora tropica]
          Length = 731

 Score =  218 bits (554), Expect = 9e-55
 Identities = 125/270 (46%), Positives = 160/270 (59%), Gaps = 4/270 (1%)

Query: 36  WFYGHHDREQRSVHDGLLQV-IPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTL 94
           W     +R  R +    L   +P AL+R EF L YQPIV L D     VEAL+RW HP L
Sbjct: 443 WAVWDRERSAREIARSTLAAGLPTALERDEFVLDYQPIVSLLDGSMRAVEALVRWQHPKL 502

Query: 95  GTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPS 154
           G L PA+FI LAE  G+IV L  +V+ QACR    WR +    R  VSVN++AR +  P+
Sbjct: 503 GLLGPAQFIGLAEETGLIVQLGEWVLRQACRDADAWRREFPEARLVVSVNLAARQVEHPA 562

Query: 155 FLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSS 214
            + MV   L ++GLPA  L+LELTE+A +      +  L  L+ LGVG+AIDDFGTG+S+
Sbjct: 563 IVDMVAGALTDSGLPAELLQLELTESAVMGTAGEPLRALHRLAGLGVGLAIDDFGTGYSN 622

Query: 215 LAYLRNLPVDMVKLAGEFIENLGGDIRGRLA---DEQITRAMIDLAFKLGIIVCAKRVET 271
           LAYLR LP+  +KLAG F+E L   +        DEQI  A++ LA  LG++V A+ VET
Sbjct: 623 LAYLRRLPIRCLKLAGPFVEGLREGVTETATSHRDEQIVDALVRLARALGLLVTAEAVET 682

Query: 272 PGQAARLRDFGCDAAQGWHFAKALPADFFT 301
             QA RLR   CD  QG+ F    PA   T
Sbjct: 683 GVQAERLRVLRCDTGQGYWFGAPGPAGEIT 712


>tr|B4VGA3|B4VGA3_9ACTO Tax_Id=465541 SubName: Full=Sensory
           box/GGDEF protein;[Streptomyces sp. Mg1]
          Length = 635

 Score =  217 bits (553), Expect = 1e-54
 Identities = 120/256 (46%), Positives = 155/256 (60%), Gaps = 3/256 (1%)

Query: 46  RSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISL 105
           R     L   +  A++RGEF L YQP+V L      GVEAL+RW HP  GTL P RFI +
Sbjct: 353 RMTRQALSSTLRPAVERGEFALEYQPLVDLESGAVRGVEALVRWNHPQFGTLTPNRFIGI 412

Query: 106 AERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRP-FVSVNVSARNIRDPSFLSMVERVLG 164
           AE +G IV L  +V+  ACR  R W+ +  +  P FVSVNV+ R + D   +  V  +L 
Sbjct: 413 AEEDGSIVQLGRWVLRTACRQARRWQIEQPSDAPVFVSVNVAVRQVWDSDLVGDVAEILA 472

Query: 165 ETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVD 224
           ETGL    L+LELTE+A +      +  LQ LS +GV IAIDDFGTG+S+LAYL  LPV 
Sbjct: 473 ETGLAPQLLQLELTESAVMGSAGRPLQALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVS 532

Query: 225 MVKLAGEFIENLGGD--IRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFG 282
           ++KL G F+     D       ADE I  A++ LA +LG+ V A+ VET GQAARLR  G
Sbjct: 533 VLKLDGSFVRGFRYDDGAHPNPADETIVEALVQLAHRLGLTVTAECVETVGQAARLRRVG 592

Query: 283 CDAAQGWHFAKALPAD 298
           CD  QGW +++A+  D
Sbjct: 593 CDTGQGWLYSRAVAPD 608


>tr|A8M737|A8M737_SALAI Tax_Id=391037 SubName: Full=Diguanylate
           cyclase/phosphodiesterase with PAS/PAC
           sensor(S);[Salinispora arenicola]
          Length = 720

 Score =  215 bits (548), Expect = 4e-54
 Identities = 128/284 (45%), Positives = 162/284 (57%), Gaps = 11/284 (3%)

Query: 21  ADSRGSGEVKDRSSGWFYGHHDREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRF 80
           A+ RG   V DR            Q      L   +PAAL+RGEF L YQPIV L D   
Sbjct: 437 AEGRGRWAVWDRERS--------AQEIARSALAAGLPAALERGEFVLHYQPIVSLRDGSM 488

Query: 81  IGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPF 140
           + VEAL+RW HP LG L P RFI LAE  G+IV L  +V+ QACR    WR +  + R  
Sbjct: 489 VAVEALVRWQHPELGLLSPVRFIGLAEETGLIVQLGAWVLRQACRDAGAWRREFPDTRLV 548

Query: 141 VSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALG 200
           VSVN++AR + DP  +  V   L ++GLPA  L+LELTE+A +      +  L  L+ LG
Sbjct: 549 VSVNLAARQVDDPIIVDTVADTLADSGLPADLLQLELTESAVMGTAGEPLRSLHRLAGLG 608

Query: 201 VGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENL---GGDIRGRLADEQITRAMIDLA 257
           V +AIDDFGTG+S+LAYLR LP+  +KLAG F+E L     ++     DEQI  A++ LA
Sbjct: 609 VRLAIDDFGTGYSNLAYLRRLPIRCLKLAGPFVEGLREGTPEMTTCHRDEQIVDALVRLA 668

Query: 258 FKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFFT 301
             L + V A+ VET  QA RLR   CD  QG+ F    P    T
Sbjct: 669 RALELSVTAEAVETGVQAERLRALRCDTGQGYWFGVPGPVGEIT 712


>tr|C4RCD7|C4RCD7_9ACTO Tax_Id=219305 SubName: Full=Diguanylate
           cyclase/phosphodiesterase;[Micromonospora sp. ATCC
           39149]
          Length = 722

 Score =  213 bits (542), Expect = 2e-53
 Identities = 124/283 (43%), Positives = 165/283 (58%), Gaps = 4/283 (1%)

Query: 19  RSADSRGSGEVKDRSSGWFYGHHDREQRSV-HDGLLQVIPAALDRGEFFLVYQPIVRLND 77
           R+AD+       +    W     +R  R +    L+  +PAALDRGEF + YQPIV L D
Sbjct: 423 RAADTTLYWAKAEGRGRWAVYDPERSARDIARSALVAGLPAALDRGEFVVHYQPIVSLLD 482

Query: 78  KRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNP 137
              + VEAL+RW HP LG + P +FI LAE  G+IV L  +V+ QACR    WR +    
Sbjct: 483 SSMVAVEALVRWQHPELGLVGPDQFIGLAEETGLIVRLGEWVLGQACRDAEAWRREFPEA 542

Query: 138 RPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELS 197
           +  VSVN++AR   DP+ +  V   LG TGLPA  L+LELTE+A +      +  L +L+
Sbjct: 543 KLVVSVNLAARQADDPAIVETVACALGRTGLPAALLQLELTESAVMGTAGEPLRALHQLA 602

Query: 198 ALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENL---GGDIRGRLADEQITRAMI 254
            LGV +AIDDFGTG+S+LAYLR +P+  +KLAG F+E +     D      DE+I  A++
Sbjct: 603 ELGVRLAIDDFGTGYSNLAYLRRMPIHCLKLAGPFVEGIRPGDADNPTDHRDERIVDALV 662

Query: 255 DLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPA 297
            LA  L + V A+ VET  QA RLR   CD  QG  F   +PA
Sbjct: 663 RLAHALEMWVTAEAVETGAQAERLRSLRCDTGQGRWFGPPVPA 705


>tr|B1VW35|B1VW35_STRGG Tax_Id=455632 SubName: Full=Putative
           uncharacterized protein;[Streptomyces griseus subsp.
           griseus]
          Length = 611

 Score =  211 bits (536), Expect = 1e-52
 Identities = 115/253 (45%), Positives = 155/253 (61%), Gaps = 3/253 (1%)

Query: 46  RSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISL 105
           R     L   +  A++RGEF L YQP+V + D    GVEAL+RW HP  G L P RF+ +
Sbjct: 343 RMTRQSLSSTLRPAVERGEFTLEYQPLVGMADGVLRGVEALVRWNHPQFGVLPPNRFVQI 402

Query: 106 AERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRP-FVSVNVSARNIRDPSFLSMVERVLG 164
           AE +G IV L  +++  ACR  R W  D  +  P F+SVNV+ R + D   ++ V ++L 
Sbjct: 403 AEEDGSIVQLGRWILRTACRQARRWELDHPDEPPLFISVNVAVRQVWDSDLVADVAQILA 462

Query: 165 ETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVD 224
           ETGL    L+LELTE+A +      +  LQ LS +GV IAIDDFGTG+S+LAYL  LPV 
Sbjct: 463 ETGLAPGLLQLELTESAVMGSGGRPLRALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVS 522

Query: 225 MVKLAGEFIENLGGD--IRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFG 282
           ++KL G F++    +       ADE I  AM+ LA +LG+ V A+ VET GQA RLR  G
Sbjct: 523 VLKLDGAFVKGFRYEDGTHPSPADETIVEAMVQLAHRLGLTVTAECVETAGQAERLRRIG 582

Query: 283 CDAAQGWHFAKAL 295
           CD  QGW +++A+
Sbjct: 583 CDTGQGWLYSRAV 595


>tr|Q93J80|Q93J80_STRCO Tax_Id=1902 SubName: Full=Putative
           uncharacterized protein SCO2817;[Streptomyces
           coelicolor]
          Length = 634

 Score =  209 bits (533), Expect = 2e-52
 Identities = 118/264 (44%), Positives = 154/264 (58%), Gaps = 11/264 (4%)

Query: 46  RSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISL 105
           R     L   +  A++RGEF L YQP+V + D R  GVEAL+RW HP  G L P RFI+L
Sbjct: 347 RMTRQALAATLRPAIERGEFALEYQPLVGMEDGRVRGVEALIRWNHPQFGVLAPNRFIAL 406

Query: 106 AERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRP-FVSVNVSARNIRDPSFLSMVERVLG 164
           AE +G IVPL  +++  AC   R W+    +  P FVSVNV+ R + D   ++ V R L 
Sbjct: 407 AEEDGSIVPLGRWILRTACHQARRWQLAHPDEPPIFVSVNVAVRQVWDSDLVADVARTLE 466

Query: 165 ETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVD 224
           ETGL    L+LELTE+A +      +  L+ LS +GV IAIDDFGTG+S+LAYL  LPV 
Sbjct: 467 ETGLAPELLQLELTESAVMGSAGRPLQVLKALSDMGVHIAIDDFGTGYSNLAYLSRLPVS 526

Query: 225 MVKLAGEFIENLGGDI----------RGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQ 274
           ++KL G F+     D               ADE I  AM+ LA +LG+ V A+ VET  Q
Sbjct: 527 VLKLDGAFVRGFQYDAVSDAAACGAGGANPADEVIVEAMVQLAHRLGLTVTAECVETSAQ 586

Query: 275 AARLRDFGCDAAQGWHFAKALPAD 298
           A RLR  GCD  QGW +++ +  D
Sbjct: 587 ATRLRRIGCDTGQGWLYSRPVAPD 610


>tr|C9Z2R5|C9Z2R5_STRSW Tax_Id=680198 SubName: Full=Putative
           diguanylate cyclase;[Streptomyces scabies]
          Length = 633

 Score =  209 bits (532), Expect = 3e-52
 Identities = 121/279 (43%), Positives = 160/279 (57%), Gaps = 22/279 (7%)

Query: 46  RSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISL 105
           R     L   + AA+ RGEF L YQP+V + +    GVEAL+RW HP  G L P RFISL
Sbjct: 345 RMTRQALSSTLRAAVGRGEFVLEYQPLVGMAEGEVRGVEALVRWHHPQFGLLTPNRFISL 404

Query: 106 AERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRP-FVSVNVSARNIRDPSFLSMVERVLG 164
           AE +G IV L  +++  ACR  R W+ D  +  P FVSVNV+ R + D   ++ V  +L 
Sbjct: 405 AEEDGSIVQLGRWILATACRQARRWQTDHPDRAPIFVSVNVAVRQVWDSDLVADVAEILA 464

Query: 165 ETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVD 224
           ETGL  H L+LELTE+A +      +  L+ LS +GV IAIDDFGTG+S+LAYL  LPV 
Sbjct: 465 ETGLAPHLLQLELTESALMGSAGRPLQALRALSDMGVRIAIDDFGTGYSNLAYLSRLPVS 524

Query: 225 MVKLAGEFI---------ENLGGDIRG------------RLADEQITRAMIDLAFKLGII 263
           ++KL G F+         E  G    G              ADE I  A++ LA +LG+ 
Sbjct: 525 VLKLDGAFVRGFQYEGGEEGAGPGAAGPEADDVEDSGQPSPADEIIVEALVQLAHRLGLS 584

Query: 264 VCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFFTE 302
           V A+ VET  QA+RLR  GCD  QGW +++A+  +   E
Sbjct: 585 VTAEGVETDAQASRLRRLGCDTGQGWLYSRAVSPERIAE 623


>tr|C9NAM3|C9NAM3_9ACTO Tax_Id=591167 SubName: Full=Diguanylate
           cyclase/phosphodiesterase with PAS/PAC
           sensor(S);[Streptomyces flavogriseus ATCC 33331]
          Length = 621

 Score =  208 bits (530), Expect = 5e-52
 Identities = 114/260 (43%), Positives = 156/260 (60%), Gaps = 3/260 (1%)

Query: 46  RSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISL 105
           R     L   +  A++RGEF L YQP+V + D    GVEAL+RW HP  G L P+RF+ +
Sbjct: 353 RMTRQALSSTLLPAVERGEFTLEYQPLVGMADGIVRGVEALVRWNHPRFGLLAPSRFVPI 412

Query: 106 AERNGMIVPLTTFVIEQACRHIRNWR-DDSTNPRPFVSVNVSARNIRDPSFLSMVERVLG 164
           AE +G IV L  +V+  AC   R W+ +   +P  F+SVNV+ R + D   ++ V  +L 
Sbjct: 413 AEEDGTIVQLGRWVLRSACLQARRWQLEHPEDPALFISVNVAVRQLWDSDLVADVAEILA 472

Query: 165 ETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVD 224
           ETGL    L+LELTE+A +      +  LQ LS +G+ IAIDDFGTG+S+LAYL  LPV 
Sbjct: 473 ETGLEPGLLQLELTESAVMGSPGRPLRVLQALSDMGIRIAIDDFGTGYSNLAYLSRLPVS 532

Query: 225 MVKLAGEFIENLGGD--IRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFG 282
           ++KL G F+     +       ADE I  AM+ LA +LG+ V A+ VET GQA RLR  G
Sbjct: 533 VLKLDGSFVRGFRYEDGAHSSPADETIVEAMVQLAHRLGLTVTAECVETSGQAERLRRIG 592

Query: 283 CDAAQGWHFAKALPADFFTE 302
           CD  QGW +++A+  +   E
Sbjct: 593 CDTGQGWLYSRAVAPERIAE 612


>tr|Q2JEA5|Q2JEA5_FRASC Tax_Id=106370 SubName: Full=Diguanylate
           cyclase/phosphodiesterase with PAS/PAC
           sensor(S);[Frankia sp.]
          Length = 725

 Score =  207 bits (527), Expect = 1e-51
 Identities = 125/288 (43%), Positives = 167/288 (57%), Gaps = 13/288 (4%)

Query: 24  RGSGEVKDRSSGWFYGHHDREQRSV-HDGLLQVIPAALDRGEFFLVYQPIVRLNDKR--- 79
           R   E K R   W     +R  R V    L  ++P AL++ +F + YQPI+ L D     
Sbjct: 416 RAKAEGKGR---WALFEAERGARQVTRHTLSTMLPRALEQDQFVVEYQPIIALGDGAGAR 472

Query: 80  -----FIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDS 134
                 +GVEAL+RW HP LG L P  FI +AE  G IVPL   V+E ACR  R W++  
Sbjct: 473 MAAGAMVGVEALVRWRHPGLGLLPPDLFIGMAEETGQIVPLGRRVLELACRQARQWQECH 532

Query: 135 TNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQ 194
            +   FVSVN++AR  R+   +  V R+L ETGL    L+LELTE+A +   +  +  L+
Sbjct: 533 PHAL-FVSVNLAARQTREAGLVEQVRRILDETGLSPDLLQLELTESAFMGTADEPLRVLR 591

Query: 195 ELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMI 254
            L+ +GV IAIDDFGTG+S+LAYLR LPV  +KLAG F+E           DE+I + ++
Sbjct: 592 GLAEMGVRIAIDDFGTGYSNLAYLRRLPVHTLKLAGPFVEGFHSARDADPGDEEIVQTLV 651

Query: 255 DLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFFTE 302
            LA  L + V A+ VETP QA RLR   CD+AQG+ FA  L A+  T+
Sbjct: 652 TLAHTLRLTVTAEGVETPMQAERLRAAACDSAQGFLFAPPLTAEEITQ 699


>tr|A1ASF8|A1ASF8_PELPD Tax_Id=338966 SubName: Full=Diguanylate
           cyclase/phosphodiesterase;[Pelobacter propionicus]
          Length = 1023

 Score =  207 bits (526), Expect = 2e-51
 Identities = 112/237 (47%), Positives = 155/237 (65%), Gaps = 5/237 (2%)

Query: 59  ALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTF 118
           A+D GEFFL YQP V ++D +  GVEAL+RW  P  G + P RFI+LAE NGMIV L  +
Sbjct: 391 AIDAGEFFLCYQPKVEIHDMKLTGVEALVRWQRPGEGVIPPDRFIALAEENGMIVRLGGW 450

Query: 119 VIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELT 178
           ++ +ACR  R W+D    PR  VSVN+SAR +R+ SF+  VER+L ETGL    L LELT
Sbjct: 451 ILGEACRQNRAWQDAGL-PRTVVSVNISARQLRENSFVEQVERILEETGLEPCYLDLELT 509

Query: 179 ENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGG 238
           E+  ++  +  + +L  L  LGVGI++DDFGTG+SSL+YL++LPVD +K+   F+ ++  
Sbjct: 510 ESVVMANSDEIVQKLTRLKQLGVGISVDDFGTGYSSLSYLKHLPVDTIKVDRSFVRDIVH 569

Query: 239 DIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKAL 295
           D      D+ I  A+I +   LG+ V A+ VET  Q   LR   C+ AQG++F+K L
Sbjct: 570 D----PDDKAIVEAVIAMGHALGLTVIAEGVETLEQLEFLRSQNCNQAQGYYFSKPL 622


>tr|A8LHD9|A8LHD9_FRASN Tax_Id=298653 SubName: Full=Diguanylate
           cyclase/phosphodiesterase with PAS/PAC
           sensor(S);[Frankia sp.]
          Length = 804

 Score =  206 bits (525), Expect = 2e-51
 Identities = 121/267 (45%), Positives = 157/267 (58%), Gaps = 9/267 (3%)

Query: 36  WFYGHHDREQRSVHDGLL-QVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTL 94
           W     DR  R    GL+ + +   LDRGEF L YQPI+ L      G EALLRW HP L
Sbjct: 533 WTAFDPDRGTREAARGLMSRSMRPGLDRGEFSLAYQPIIDLRHGTVAGAEALLRWDHPRL 592

Query: 95  GTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPS 154
           G   P  FI+LAE +G IV L  +V+E+AC   R+W         F+SVN+SAR +R+P 
Sbjct: 593 GPTRPGEFIALAEDSGFIVQLGLWVLERACETARDWP-----AHMFISVNLSARQLREPG 647

Query: 155 FLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSS 214
            +  V++VL  TGLP   L+LELTE   +      +T L  L+ LGV I IDDFGTG+S+
Sbjct: 648 LVGAVKKVLDRTGLPPRRLQLELTETVLMDSGGDQVTALHALNDLGVRIVIDDFGTGWSN 707

Query: 215 LAYLRNLPVDMVKLAGEFIENLG-GDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPG 273
             YL  +PV  +KLAG F+E LG G   GR  D+ +  A+++ A +L + V A+ VE P 
Sbjct: 708 FVYLSTMPVRGLKLAGLFVEKLGRGTEPGR--DDHLVEAIVEFARRLRLSVTAEGVEEPE 765

Query: 274 QAARLRDFGCDAAQGWHFAKALPADFF 300
           QAA LR FG D  QG  F + +PAD F
Sbjct: 766 QAAALRSFGADLGQGHLFGEPVPADEF 792


>tr|C7PY35|C7PY35_CATAD Tax_Id=479433 SubName: Full=Diguanylate
           cyclase/phosphodiesterase;[Catenulispora acidiphila]
          Length = 558

 Score =  206 bits (525), Expect = 2e-51
 Identities = 115/254 (45%), Positives = 153/254 (60%), Gaps = 12/254 (4%)

Query: 56  IPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPL 115
           +PAA++ G+F+  YQPIV L+D    GVEAL+RW HP  G + P RFISLAE +G+IV L
Sbjct: 290 LPAAVESGQFYCEYQPIVSLSDGAVTGVEALVRWRHPRFGIVPPDRFISLAEDSGLIVEL 349

Query: 116 TTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRL 175
              ++ +AC+    W D    P P VSVNV+ R  RDP  +  V   L E+GL    LRL
Sbjct: 350 GRRILSEACQAAATWPDAPGQPAPPVSVNVAVRQCRDPRLMGHVLSALAESGLAPQRLRL 409

Query: 176 ELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIEN 235
           E+TE+A L  D+A+   L+ L+  GV IA+DDFGTG+S+L++LR LPV ++K+ G F+  
Sbjct: 410 EITESALLPGDDAAQATLRALADKGVAIAVDDFGTGYSNLSHLRRLPVHILKIDGTFVAG 469

Query: 236 LG-----GDIRGRL-------ADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGC 283
           L      G   G         ADEQI   +  L   LG+ V A+ VET GQ   +R  G 
Sbjct: 470 LASAGAVGAAAGAAGTTGPCGADEQIIATVTALGHALGLTVTAEGVETAGQLETVRRLGV 529

Query: 284 DAAQGWHFAKALPA 297
           D  QGW F++ALPA
Sbjct: 530 DTGQGWLFSRALPA 543


>tr|B5GAU1|B5GAU1_9ACTO Tax_Id=465543 SubName: Full=Putative
           uncharacterized protein;[Streptomyces sp. SPB74]
          Length = 716

 Score =  206 bits (524), Expect = 3e-51
 Identities = 110/248 (44%), Positives = 157/248 (63%), Gaps = 2/248 (0%)

Query: 51  GLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNG 110
           GL   +PAAL+RGEFF+ YQP+V L D    G EAL+RW+HP  GT+ P RFI LAE  G
Sbjct: 456 GLTTSLPAALERGEFFIEYQPLVDLGDGTVHGAEALVRWSHPQHGTIGPDRFIPLAEHTG 515

Query: 111 MIVPLTTFVIEQACRHIRNWRDDSTNPRPF-VSVNVSARNIRDPSFLSMVERVLGETGLP 169
           +IVPL  +V++Q+ R  R W+++   P P  V+VN+S   ++ P  ++    +L  TGLP
Sbjct: 516 LIVPLGRWVLDQSARQARLWQEEHGGPAPLRVNVNLSPCQLQHPRLVADTVEILERTGLP 575

Query: 170 AHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLA 229
             AL LE+TE+A +  D+  +  L+ L+ +GV IA+DDFGTG+S+LA LR LPV ++KL 
Sbjct: 576 PGALCLEVTESALIGADDDLLKPLRRLAEMGVDIALDDFGTGYSNLANLRRLPVSVLKLD 635

Query: 230 GEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGW 289
             F + +         D +I   ++ LA  L + V  + VET  QA +LR+ GCD AQGW
Sbjct: 636 RAFTQGM-QQFPADPVDLKIVEGIVALAHSLDLAVTVEGVETSAQADQLRELGCDTAQGW 694

Query: 290 HFAKALPA 297
           ++A+  PA
Sbjct: 695 YYARPGPA 702


>tr|B4V5X3|B4V5X3_9ACTO Tax_Id=465541 SubName: Full=Putative
           uncharacterized protein;[Streptomyces sp. Mg1]
          Length = 709

 Score =  206 bits (524), Expect = 3e-51
 Identities = 111/243 (45%), Positives = 154/243 (63%), Gaps = 1/243 (0%)

Query: 51  GLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNG 110
           GL   +PAAL+RGEFF+ YQP+V L+D    G EAL+RW+HP  G L P RFI LAER G
Sbjct: 449 GLTNALPAALERGEFFIEYQPLVHLHDGSVHGAEALVRWSHPQYGVLGPDRFIPLAERTG 508

Query: 111 MIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPA 170
           +IVPL  +V+E+A R  RNW+         V+VN+S   +  P  ++    VL  +GL  
Sbjct: 509 LIVPLGRWVLEEAVRQARNWQRQHGCSALRVNVNLSPTQLHHPGLVADTVAVLENSGLAP 568

Query: 171 HALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAG 230
            AL LE+TE+A +  D+  +  L+ L+ALGV IA+DDFGTG+S+LA LR LPV ++KL  
Sbjct: 569 GALCLEVTESALIGADDELLEPLRRLAALGVDIALDDFGTGYSNLANLRRLPVSVLKLDR 628

Query: 231 EFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWH 290
            F + +       + D +I   ++ LA  L + V  + VET  QAA+LR+ GCD AQGW+
Sbjct: 629 SFTQGMQQQPADPV-DVKIVEGIVALAHSLELAVTVEGVETGAQAAQLRELGCDTAQGWY 687

Query: 291 FAK 293
           +A+
Sbjct: 688 YAR 690


>tr|B5HHK8|B5HHK8_STRPR Tax_Id=457429 SubName: Full=Putative
           uncharacterized protein;[Streptomyces pristinaespiralis
           ATCC 25486]
          Length = 720

 Score =  201 bits (511), Expect = 9e-50
 Identities = 109/244 (44%), Positives = 153/244 (62%), Gaps = 2/244 (0%)

Query: 51  GLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNG 110
           GL   +PAALDRGEFF+ YQP+V L D    G EAL+RW HP  G L P RFI LAER G
Sbjct: 462 GLTNALPAALDRGEFFIEYQPLVHLGDGSVHGAEALVRWCHPQHGVLGPDRFIPLAERTG 521

Query: 111 MIVPLTTFVIEQACRHIRNWRDDSTNPRPF-VSVNVSARNIRDPSFLSMVERVLGETGLP 169
           +IVPL  +V+++A R  R W    T+  P  ++VN+S   ++ P  ++    VL  +GL 
Sbjct: 522 LIVPLGRWVLQEAVRQARFWSRRHTDGGPLRINVNLSPAQLQHPGLVADTVDVLERSGLE 581

Query: 170 AHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLA 229
             AL LE+TE+A +  DE  +  L++L+ +GV IA+DDFGTG+S+LA LR LPV ++KL 
Sbjct: 582 PGALCLEVTESALIGADEDRLKPLRQLAEMGVDIALDDFGTGYSNLANLRRLPVSVLKLD 641

Query: 230 GEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGW 289
             F + +       + D +I   ++ LA  L + V  + VET  QA +LR+ GCD AQGW
Sbjct: 642 RSFTQGMQRHPADPV-DLKIVEGIVSLAHSLELAVTVEGVETAAQAEQLRELGCDTAQGW 700

Query: 290 HFAK 293
           ++A+
Sbjct: 701 YYAR 704


>tr|Q3K7G5|Q3K7G5_PSEPF Tax_Id=205922 SubName: Full=Conserved
           GGDEF/EAL domain protein; Flags: Precursor;[Pseudomonas
           fluorescens]
          Length = 624

 Score =  200 bits (508), Expect = 2e-49
 Identities = 118/285 (41%), Positives = 166/285 (58%), Gaps = 17/285 (5%)

Query: 19  RSADSRGSGEVKDRSSGWFY---GHHDREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRL 75
           RSA   G  E+     G+F        REQ+S+  G+ Q    AL R EF L YQP + L
Sbjct: 339 RSAKENGPNEI-----GFFIEAMNQRAREQQSIESGIRQ----ALQRHEFVLHYQPKIEL 389

Query: 76  NDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDST 135
              R +G EAL+RW  P  G + P+ FI +AE +G+IVPL+ +V+ +ACR  R W+    
Sbjct: 390 ASGRVVGAEALVRWQKPGHGWVYPSEFIPVAEDSGLIVPLSKWVLAEACRQTREWQQAGL 449

Query: 136 NPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQE 195
            P   +SVN SA + R   F+  +E+VL +TGL    L LE+TE   +   +A+++ L  
Sbjct: 450 PPIR-MSVNTSAIDFRQRHFVEGIEQVLAQTGLDPRLLELEITEGVLMQNVDATMSALNR 508

Query: 196 LSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMID 255
           L ALGV +AIDDFGTG+SSL+YLR  P+D++K+   FI  L  D     +D  +  A+I 
Sbjct: 509 LKALGVRLAIDDFGTGYSSLSYLRRFPIDVLKIDQSFIRGLSHD----SSDAALVGAIIS 564

Query: 256 LAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPADFF 300
           L   L + V A+ VET  + A L+D  C+  QG++F+KALP D F
Sbjct: 565 LGKSLNLNVIAEGVETAQELAFLKDHHCEEGQGYYFSKALPVDAF 609


>tr|C9Z514|C9Z514_STRSW Tax_Id=680198 SubName: Full=Putative
           uncharacterized protein;[Streptomyces scabies]
          Length = 714

 Score =  200 bits (508), Expect = 2e-49
 Identities = 112/252 (44%), Positives = 151/252 (59%), Gaps = 5/252 (1%)

Query: 51  GLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNG 110
           GL   +PAALDRGEFF+ YQP+V L D    G EAL+RW HP  G L P RFI LAER G
Sbjct: 452 GLTTALPAALDRGEFFIEYQPLVHLGDGTVRGAEALVRWLHPQHGVLGPDRFIPLAERTG 511

Query: 111 MIVPLTTFVIEQACRHIRNWRDDSTNPRPF----VSVNVSARNIRDPSFLSMVERVLGET 166
           +IVPL  +V+EQ+ R  R W++     R      V+VN+S   +  P  +     +L   
Sbjct: 512 LIVPLGRWVLEQSVRQARAWQERGGGTRAAGPLRVNVNLSPCQLTHPGLVQDTVDILERA 571

Query: 167 GLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMV 226
           GLP  AL LE+TE+A +  D+  +  L+ LS +GV IA+DDFGTG+S+LA LR LPV ++
Sbjct: 572 GLPPDALCLEVTESALIGADDDLLKPLRRLSEMGVDIALDDFGTGYSNLANLRRLPVRVL 631

Query: 227 KLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAA 286
           KL   F +++         D +I   ++ LA  L + V  + VET  QA +LR  GCD A
Sbjct: 632 KLDRSFTQSM-QRFPADPVDLKIVEGIVSLAHSLDLAVTVEGVETGAQAEQLRILGCDTA 690

Query: 287 QGWHFAKALPAD 298
           QGW++A+  P D
Sbjct: 691 QGWYYARPGPPD 702


>tr|Q3A628|Q3A628_PELCD Tax_Id=338963 SubName: Full=Diguanylate
            cyclase/phosphodiesterase with PAS/PAC
            sensor(S);[Pelobacter carbinolicus]
          Length = 1063

 Score =  197 bits (502), Expect = 1e-48
 Identities = 110/240 (45%), Positives = 149/240 (62%), Gaps = 5/240 (2%)

Query: 58   AALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTT 117
            +AL  GE  LVYQP + L   R  G+EALLRW  P  GT+ PARFI LAE  G+I PL  
Sbjct: 810  SALKEGEMQLVYQPQIDLGKVRITGMEALLRWQSPEEGTISPARFIPLAEETGLIYPLGE 869

Query: 118  FVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLEL 177
            +V++QACR    W+    +P   V+VN+SA+    P     ++++L ETGL  H L LE+
Sbjct: 870  WVLQQACRQGAIWQKTEASPL-CVAVNLSAKQFHQPDLAKNIKKILRETGLSPHLLELEI 928

Query: 178  TENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLG 237
            TE+  L   EA+I  L EL  LGV  +IDDFGTG+SSL+YL+ LP+D +K+A EF+ ++ 
Sbjct: 929  TESVFLENMEAAIEALTELKKLGVQFSIDDFGTGYSSLSYLKKLPIDRIKIAQEFVRDID 988

Query: 238  GDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPA 297
             D      D+ I +A I +A  LG+ + A+ VE   Q A L   GC A QG++FAK +PA
Sbjct: 989  TDD----GDKAIIKATIAMAKSLGMKLIAEGVENHQQLAFLLLHGCHAMQGYYFAKPMPA 1044


>tr|Q1AVS2|Q1AVS2_RUBXD Tax_Id=266117 SubName: Full=Diguanylate
           cyclase/phosphodiesterase; Flags: Precursor;[Rubrobacter
           xylanophilus]
          Length = 762

 Score =  197 bits (502), Expect = 1e-48
 Identities = 106/236 (44%), Positives = 151/236 (63%), Gaps = 5/236 (2%)

Query: 58  AALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTT 117
           AAL+RGEF + YQPIV       + VEAL+RW  P  GT+ PA F+S+AE +G+IVP+  
Sbjct: 508 AALERGEFAVHYQPIVSFATGEVVEVEALVRWERPGRGTVGPAEFLSVAEESGLIVPIGR 567

Query: 118 FVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLEL 177
           +V+ +ACR +R W+   +     ++VN+SA  +  P  +  VE  LG +GL A  L+LE+
Sbjct: 568 WVLREACRQVREWQKGGSRELA-LAVNLSASQLHHPRLVREVEEALGLSGLEARHLKLEI 626

Query: 178 TENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLG 237
           TE A++     +  RL+ELSALGV IA+DDFG+G+S+L+YLR  PVD +K+   FIE +G
Sbjct: 627 TEQAAVEDAREAARRLEELSALGVRIALDDFGSGYSALSYLRTFPVDTLKIDRSFIEGIG 686

Query: 238 GDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAK 293
            D++       I  A+I LA  L + V A+  ET  Q A LR  GCD AQG++F++
Sbjct: 687 RDLQA----TSIVGAVIALAKSLNMCVTAEGTETEEQLAHLRSLGCDLAQGYYFSR 738


>tr|B7GKP9|B7GKP9_ANOFW Tax_Id=491915 SubName: Full=Multidomain
           signal transduction protein (Contains PAS, GGDEF and EAL
           domains);[Anoxybacillus flavithermus]
          Length = 641

 Score =  197 bits (501), Expect = 1e-48
 Identities = 109/269 (40%), Positives = 165/269 (61%), Gaps = 9/269 (3%)

Query: 30  KDRSSGWFYGHHDREQRSVHDGLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRW 89
           K+R  G+ + H  + ++ + +   Q +P AL   +F+L YQP V L++K  +GVEAL+RW
Sbjct: 365 KERGKGYHFYHPQQNRKRMIE---QELPLALLNNQFYLCYQPKVSLDNKSIMGVEALMRW 421

Query: 90  AHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSARN 149
            HPTLG + P  FIS+AE+NG I  +TT+V+++ACR ++ WR  +  P   ++VN+S   
Sbjct: 422 THPTLGAISPLEFISIAEKNGFIFEITTWVLKEACRQVKQWR--THFPTLKLAVNLSPFL 479

Query: 150 IRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFG 209
           +    F++ V+ +L ET  P + L LE+TE+  +   E     L EL  +G+ +AIDDFG
Sbjct: 480 LNRKEFVTHVKNILQETQFPPNYLILEITESGLMENIETGKHILTELQQIGIQVAIDDFG 539

Query: 210 TGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRV 269
           TGFSSLAY+RNLPV ++K+   FI     DI     D  I   +I LA  L + V A+ V
Sbjct: 540 TGFSSLAYIRNLPVSLLKIDRSFIR----DITDNSKDATIVDTIIHLAKSLDLQVLAEGV 595

Query: 270 ETPGQAARLRDFGCDAAQGWHFAKALPAD 298
           E   Q + L+   CD AQG++F+++L A+
Sbjct: 596 ERDDQVSLLQKMDCDFAQGFYFSQSLEAE 624


>tr|C9NJG7|C9NJG7_9ACTO Tax_Id=591167 SubName: Full=Diguanylate
           cyclase/phosphodiesterase with PAS/PAC
           sensor(S);[Streptomyces flavogriseus ATCC 33331]
          Length = 724

 Score =  197 bits (501), Expect = 1e-48
 Identities = 106/244 (43%), Positives = 151/244 (61%), Gaps = 2/244 (0%)

Query: 51  GLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNG 110
           GL   +P ALDRGEFF+ YQP+V L D    G EAL+RW HP  G L P RFI LAE  G
Sbjct: 466 GLTTALPTALDRGEFFIEYQPLVHLGDGSVHGAEALVRWCHPQHGVLGPDRFIPLAEHTG 525

Query: 111 MIVPLTTFVIEQACRHIRNWRDDSTNPRPF-VSVNVSARNIRDPSFLSMVERVLGETGLP 169
           +IVPL  +V+E++ R    W++  T+  P  ++VN+S   +  PS ++    VL  +GL 
Sbjct: 526 LIVPLGRWVLEESVRQANFWKERHTDGGPLRINVNLSPTQLHHPSLVAETVDVLERSGLE 585

Query: 170 AHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLA 229
             AL LE+TE+A +  D+  +  L++L+ +GV IA+DDFGTG+S+LA LR LPV ++KL 
Sbjct: 586 PGALCLEVTESALIGADDDLLKPLRQLAEMGVDIALDDFGTGYSNLANLRRLPVSVLKLD 645

Query: 230 GEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGW 289
             F + +       + D +I   ++ LA  L + V  + VET  QA +LR  GCD AQGW
Sbjct: 646 RSFTQGMQHHPADPV-DLKIVEGIVSLAHSLDLAVTVEGVETGAQAEQLRQIGCDTAQGW 704

Query: 290 HFAK 293
           ++A+
Sbjct: 705 YYAR 708


>tr|C0U555|C0U555_9ACTO Tax_Id=526225 SubName: Full=PAS domain
           S-box/diguanylate cyclase (GGDEF) domain-containing
           protein;[Geodermatophilus obscurus DSM 43160]
          Length = 722

 Score =  196 bits (498), Expect = 3e-48
 Identities = 121/283 (42%), Positives = 164/283 (57%), Gaps = 5/283 (1%)

Query: 19  RSADSRGSGEVKDRSSGWFYGHHDREQRSV-HDGLLQVIPAALDRGEFFLV-YQPIVRLN 76
           R+AD        D  S W     +R+ R +    L   +PAAL  GE  LV YQP+ RL 
Sbjct: 434 RAADMTLYWAKADGRSQWALFEPERDAREITRYRLSSALPAAL-AGEHLLVHYQPLRRLA 492

Query: 77  DKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTN 136
           D R  GVEAL+RW HP +G L P  F+ LAE +GMIVPL   V+  ACR   +W    ++
Sbjct: 493 DGRLHGVEALVRWEHPRMGLLGPESFVGLAEESGMIVPLGRHVLRAACRQAFSWFGAGSS 552

Query: 137 PRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQEL 196
             P+VSVN+++R +RD   +  V   L ++GL    L+LE+TE+A L  D  +   L  L
Sbjct: 553 G-PYVSVNLASRQLRDEHLVDDVRTALSDSGLHPQQLQLEITESAVLGTDPLTGHTLDAL 611

Query: 197 SALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDL 256
           + +GV +AIDDFGTG+S+LA+LR LP+D +KL G F+  L  D      D Q+  ++I L
Sbjct: 612 AGMGVRLAIDDFGTGYSNLAHLRRLPLDELKLDGSFLRGLRSDDAVDPVDVQLVGSIISL 671

Query: 257 AFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAK-ALPAD 298
           A  LG+ V A+ VET  Q   LR+  CDA QG +  + A PAD
Sbjct: 672 AHLLGLTVTAEGVETQAQVTILRELDCDAGQGTYLGRPAEPAD 714


>tr|Q1ASD1|Q1ASD1_RUBXD Tax_Id=266117 SubName: Full=Diguanylate
            cyclase/phosphodiesterase with PAS/PAC and GAF
            sensor(S);[Rubrobacter xylanophilus]
          Length = 1101

 Score =  196 bits (497), Expect = 4e-48
 Identities = 117/271 (43%), Positives = 155/271 (57%), Gaps = 12/271 (4%)

Query: 28   EVKDRSSGWFYGHHDREQRSVHDGLL--QVIPAALDRGEFFLVYQPIVRLNDKRFIGVEA 85
            E KDR   + +G      R+ HD L     +  A+ R E  L YQP+VRL D R +  EA
Sbjct: 810  EGKDRYRVFDFGM----SRTAHDRLRLENDLRRAVGRDELRLYYQPVVRLGDGRVVAFEA 865

Query: 86   LLRWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNV 145
            LLRW HP  G LLP RF+ LAE  GMIV +   V+E AC     WR     P   VSVN+
Sbjct: 866  LLRWEHPRRGILLPDRFVPLAEETGMIVGIGRRVLELACSRAAGWRRQE--PSLAVSVNI 923

Query: 146  SARNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAI 205
            SAR +  P F+  V R+L  TGL    L LE+TE+A++     +   LQ L   GV +A+
Sbjct: 924  SARQLVRPDFVEEVGRILQRTGLEPEGLVLEVTESAAMDEPGEAARALQRLRERGVRLAL 983

Query: 206  DDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVC 265
            DDFGTG+SSL+YLR LPV  +K+   F+E LGGD    +    +   +I L+ +LG    
Sbjct: 984  DDFGTGYSSLSYLRRLPVCFLKIDRSFVEGLGGDSGSGV----LVGGVIALSRELGFEPV 1039

Query: 266  AKRVETPGQAARLRDFGCDAAQGWHFAKALP 296
            A+ +ETPGQ  RL + GC+  QG++FA  +P
Sbjct: 1040 AEGIETPGQLERLLELGCELGQGYYFASPMP 1070


>tr|B8DSE5|B8DSE5_DESVM Tax_Id=883 SubName: Full=Diguanylate
            cyclase/phosphodiesterase with PAS/PAC and GAF
            sensor(S);[Desulfovibrio vulgaris]
          Length = 1251

 Score =  196 bits (497), Expect = 4e-48
 Identities = 101/236 (42%), Positives = 147/236 (62%), Gaps = 5/236 (2%)

Query: 59   ALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTF 118
            A+ R + +L YQP++ ++  R +G EAL+RW HPT G + PARFI +AE  G+I+ +  +
Sbjct: 956  AMRRKQLYLEYQPVLAVDGARLLGFEALVRWRHPTEGAVPPARFIPMAEETGLILRIGQW 1015

Query: 119  VIEQACRHIRNWRDDSTNPRP-FVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLEL 177
            V+EQA   +  WR         +VSVN+SAR    P+    V R+L +TGLP  AL+LE+
Sbjct: 1016 VLEQAAATLARWRATLPGAHDLYVSVNLSARQASQPNLTGRVARILSDTGLPPEALKLEI 1075

Query: 178  TENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLG 237
            TE A +   + ++ RL+ L  LGVGI IDDFGTG+SSLAYL+  PVD +K+   F+  + 
Sbjct: 1076 TETAIMKDPDGALQRLEALRRLGVGIGIDDFGTGYSSLAYLQRFPVDTLKVDRSFVSAVA 1135

Query: 238  GDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAK 293
            GD   R    +I R ++ L   LG+ V A+ VET  Q A + + GC + QG+HF++
Sbjct: 1136 GDAENR----EIVRTVVTLGRSLGLHVVAEGVETAEQFAIVAELGCHSVQGYHFSR 1187


>tr|Q3SJL3|Q3SJL3_THIDA Tax_Id=292415 SubName: Full=Putative
           diguanylate cyclase/phosphodiesterase (GGDEF & EAL
           domains) with PAS/PAC sensor(S) and Response Regulator
           Receiver modulation;[Thiobacillus denitrificans]
          Length = 836

 Score =  195 bits (495), Expect = 6e-48
 Identities = 114/243 (46%), Positives = 144/243 (59%), Gaps = 5/243 (2%)

Query: 59  ALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTF 118
           ALDRGEF L YQP + L D R  GVEALLRW HP  G + P  F+ L E  G+IVP+  +
Sbjct: 576 ALDRGEFRLHYQPQLDLRDNRIAGVEALLRWKHPRDGVIAPGDFVPLLEDTGLIVPVGEW 635

Query: 119 VIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELT 178
           V+  AC   R  R+    P   +SVNVSAR  R+ + L  VE+VL E  +P H L LE+T
Sbjct: 636 VLRNACTQYRACRESGVAPVR-ISVNVSARQFREDTLLRQVEQVLREECMPPHHLELEIT 694

Query: 179 ENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGG 238
           E+ ++    A+   L  L ALGV +AIDDFGTG+SSLAYL+  P+D +K+   FI +   
Sbjct: 695 ESTAMQDVAATGDILAALDALGVRLAIDDFGTGYSSLAYLKRFPLDALKIDQAFIRDAPR 754

Query: 239 DIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPAD 298
           D         I  A I L  KLG+ V A+ VET  Q A LR   CD  QG+HF++ LPAD
Sbjct: 755 DAN----IAAIAEASISLGHKLGLEVVAEGVETAEQLAFLRRRACDLIQGFHFSRPLPAD 810

Query: 299 FFT 301
             T
Sbjct: 811 ALT 813


>tr|Q9RCY2|Q9RCY2_STRCO Tax_Id=1902 SubName: Full=Putative
           uncharacterized protein SCO0928;[Streptomyces
           coelicolor]
          Length = 714

 Score =  194 bits (494), Expect = 8e-48
 Identities = 109/252 (43%), Positives = 152/252 (60%), Gaps = 5/252 (1%)

Query: 51  GLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNG 110
           GL   +PAAL+RGEFF+ YQP+V L D    G EAL+RW HP  G L P RFI LAE  G
Sbjct: 452 GLTTALPAALERGEFFIEYQPLVHLGDGSVRGAEALVRWLHPQHGVLGPDRFIPLAEHTG 511

Query: 111 MIVPLTTFVIEQACRHIRNWRD---DSTNPRPF-VSVNVSARNIRDPSFLSMVERVLGET 166
           +IVPL  +V+EQ+ R  R WR+   +S    P  ++VN+S   +  P  +     +L  T
Sbjct: 512 LIVPLGRWVLEQSVRQARVWRERYGESGAAGPLRINVNLSPCQLTHPGLVQDTVEILERT 571

Query: 167 GLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMV 226
           G+   AL LE+TE+A +  D+  +  L+ L+ +GV IA+DDFGTG+S+LA LR LPV ++
Sbjct: 572 GVAPDALCLEVTESALIGADDDLLKPLRRLAEMGVDIALDDFGTGYSNLANLRRLPVSVL 631

Query: 227 KLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAA 286
           KL   F +++         D +I   ++ LA  L + V  + VET  QA +LR  GCD A
Sbjct: 632 KLDRSFTQSM-QQFPADPVDLKIVEGIVALAHSLDLAVTVEGVETGAQAEQLRILGCDTA 690

Query: 287 QGWHFAKALPAD 298
           QGW++A+  P D
Sbjct: 691 QGWYYARPGPPD 702


>tr|B8GNC0|B8GNC0_THISH Tax_Id=396588 SubName: Full=Signal
           transduction protein containing a membrane domain an EAL
           and a GGDEF domain; Flags: Precursor;[Thioalkalivibrio
           sp.]
          Length = 655

 Score =  194 bits (494), Expect = 8e-48
 Identities = 108/243 (44%), Positives = 150/243 (61%), Gaps = 5/243 (2%)

Query: 59  ALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTTF 118
           AL+R EF L YQP VR  D   IG+EAL+RW HP  G   P  FI +AE  G+I PL  +
Sbjct: 403 ALEREEFTLHYQPRVRTQDDVMIGMEALVRWHHPDKGLTAPDAFIPMAEETGLITPLGLW 462

Query: 119 VIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLELT 178
           V+  ACR  + W      P   ++VN+S R +R P  +S ++ +L +TGLPA +L LELT
Sbjct: 463 VLRTACRQAQTWMRLYGEPI-HMAVNLSMRQLRQPDLVSQIDAILRDTGLPASSLELELT 521

Query: 179 ENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLGG 238
           E+  ++ D  ++T L EL ALGV +AIDDFGTG+SSLAYL+ LP+D +K+   F+ ++  
Sbjct: 522 ESVLMAGDGHTLTALAELKALGVRLAIDDFGTGYSSLAYLKRLPIDALKIDRSFVSDIPH 581

Query: 239 DIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPAD 298
           D     +D  I   +I +A  LG+ V A+ VETP Q A L+  GCD+ QG+ F+  + A 
Sbjct: 582 D----ASDMAIASTIIAMARTLGLEVVAEGVETPEQLAFLKKEGCDSYQGFGFSPPVDAQ 637

Query: 299 FFT 301
             T
Sbjct: 638 AMT 640


>tr|Q39XK0|Q39XK0_GEOMG Tax_Id=269799 SubName: Full=Diguanylate
           cyclase/phosphodiesterase;[Geobacter metallireducens]
          Length = 736

 Score =  194 bits (493), Expect = 1e-47
 Identities = 106/275 (38%), Positives = 159/275 (57%), Gaps = 7/275 (2%)

Query: 30  KDRSSGWFYGHHDREQRSVHDG--LLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALL 87
           K+     ++ H     R  H+   L   +  AL+R EFFL +QPI+ +     +G EAL+
Sbjct: 453 KEAGRNGYHFHSPEMNRKAHERMELEMSLRQALERDEFFLEFQPIINVGGDCLVGAEALV 512

Query: 88  RWAHPTLGTLLPARFISLAERNGMIVPLTTFVIEQACRHIRNWRDDSTNPRPFVSVNVSA 147
           RW HP  G ++P  FI LAE +G+I+PL  +V+ +AC  ++ WRD    P   +SVN+S 
Sbjct: 513 RWQHPAQGRVMPGTFIPLAESSGLIIPLGEWVLRKACEKMKEWRDAGLPPVK-LSVNISG 571

Query: 148 RNIRDPSFLSMVERVLGETGLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDD 207
           R     +F ++V+ VL ETG+ A AL+ ELTE + +    A+++ L +L  L + I +DD
Sbjct: 572 RQFEQRNFTALVDEVLKETGVDARALQFELTETSLMKDAGATVSALYKLKELDLRIVVDD 631

Query: 208 FGTGFSSLAYLRNLPVDMVKLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAK 267
           FGTG+SSLAYL+N P+D +K+   F+ ++  D      D  I  A++ +A KL + V A+
Sbjct: 632 FGTGYSSLAYLKNFPIDHIKIDRSFVMDICDD----PDDRSIVEAIVAMANKLNLDVVAE 687

Query: 268 RVETPGQAARLRDFGCDAAQGWHFAKALPADFFTE 302
            VET  Q   L D GC   QG+ F + LP + F E
Sbjct: 688 GVETREQRDLLLDLGCHEMQGFLFHRPLPEEKFVE 722


>tr|A1K2X7|A1K2X7_AZOSB Tax_Id=62928 (morA)SubName:
            Full=GGDEF/EAL/PAS/PAC/GAF-domain containing
            protein;[Azoarcus sp.]
          Length = 1070

 Score =  194 bits (493), Expect = 1e-47
 Identities = 107/243 (44%), Positives = 143/243 (58%), Gaps = 6/243 (2%)

Query: 58   AALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNGMIVPLTT 117
            +AL+ GE  L +QP V     + IG EALLRW HP LG + P RFI LAE  G+I P+  
Sbjct: 825  SALENGELHLAFQPQVDGGSGQVIGAEALLRWQHPELGAVPPVRFIPLAEETGLIGPIGE 884

Query: 118  FVIEQACRHIRNWRDDSTNPRPFVSVNVSARNIRDPSFLSMVERVLGETGLPAHALRLEL 177
            +V+  ACR  R W       R  ++VNVSAR  R P   + +  +L ETGLP   L LEL
Sbjct: 885  WVLRAACRQARQWEQAGRRLR--IAVNVSARQFRSPDLPARIAEILDETGLPPALLELEL 942

Query: 178  TENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMVKLAGEFIENLG 237
            TE+  +   E +   L  L  LGV +A+DDFGTG+SS AYL+  P+D +K+   F+ ++ 
Sbjct: 943  TESMLMGDAEQAEEMLHRLKQLGVSLALDDFGTGYSSFAYLQRFPIDTLKIDQSFVRSMV 1002

Query: 238  GDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAAQGWHFAKALPA 297
              +RG    E I  A+I LA  LG+ V A+ VETP Q  +L +FGCD  QG+ F + +PA
Sbjct: 1003 AGVRG----EAIVVAIIALAHSLGMRVIAEGVETPLQQRQLFEFGCDELQGYLFGRPVPA 1058

Query: 298  DFF 300
              F
Sbjct: 1059 AEF 1061


>tr|A0ADW3|A0ADW3_STRAM Tax_Id=278992 SubName: Full=Putative
           uncharacterized protein;[Streptomyces ambofaciens ATCC
           23877]
          Length = 714

 Score =  194 bits (493), Expect = 1e-47
 Identities = 109/252 (43%), Positives = 153/252 (60%), Gaps = 5/252 (1%)

Query: 51  GLLQVIPAALDRGEFFLVYQPIVRLNDKRFIGVEALLRWAHPTLGTLLPARFISLAERNG 110
           GL   +PAAL+RGEFF+ YQP+V L D    G EAL+RW HP  G L P RFI LAE  G
Sbjct: 452 GLTTALPAALERGEFFIEYQPLVHLGDGSVHGAEALVRWLHPQHGVLGPDRFIPLAEHTG 511

Query: 111 MIVPLTTFVIEQACRHIRNWRD---DSTNPRPF-VSVNVSARNIRDPSFLSMVERVLGET 166
           +IVPL  +V+EQ+ R  R WR+   +ST   P  ++VN+S   +  P  +     +L  T
Sbjct: 512 LIVPLGRWVLEQSVRQARVWRERYGESTAAGPLRINVNLSPCQLTHPGLVQDTVDILERT 571

Query: 167 GLPAHALRLELTENASLSIDEASITRLQELSALGVGIAIDDFGTGFSSLAYLRNLPVDMV 226
           G+   AL LE+TE+A +  D+  +  L+ L+ +GV IA+DDFGTG+S+LA LR LPV ++
Sbjct: 572 GVAPDALCLEVTESALIGADDDLLKPLRRLAEMGVDIALDDFGTGYSNLANLRRLPVSVL 631

Query: 227 KLAGEFIENLGGDIRGRLADEQITRAMIDLAFKLGIIVCAKRVETPGQAARLRDFGCDAA 286
           KL   F +++         D +I   ++ LA  L + V  + VET  QA +LR  GCD A
Sbjct: 632 KLDRSFTQSM-QRFPADPVDLKIVEGIVALAHSLDLTVTVEGVETGAQAEQLRILGCDTA 690

Query: 287 QGWHFAKALPAD 298
           QGW++A+  P +
Sbjct: 691 QGWYYARPGPPE 702


  Database: Amellifera_nr
    Posted date:  Jan 15, 2010  5:10 AM
  Number of letters in database: 3,808,957,724
  Number of sequences in database:  11,153,314
  
Lambda     K      H
   0.323    0.139    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11153314
Number of Hits to DB: 2,198,079,480
Number of extensions: 89715654
Number of successful extensions: 238659
Number of sequences better than 10.0: 10144
Number of HSP's gapped: 221086
Number of HSP's successfully gapped: 10148
Length of query: 302
Length of database: 3,808,957,724
Length adjustment: 136
Effective length of query: 166
Effective length of database: 2,292,107,020
Effective search space: 380489765320
Effective search space used: 380489765320
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 80 (35.4 bits)