BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= ML2324
         (607 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,153,314 sequences; 3,808,957,724 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|Q9CB76|LEU1_MYCLE Tax_Id=1769 (leuA)RecName: Full=2-isopropyl...  1166   0.0  
tr|B8ZT16|B8ZT16_MYCLB Tax_Id=561304 (leuA)SubName: Full=2-isopr...  1166   0.0  
tr|B2HKD3|B2HKD3_MYCMM Tax_Id=216594 (leuA)SubName: Full=2-isopr...   995   0.0  
tr|A0Q9T9|A0Q9T9_MYCA1 Tax_Id=243243 (leuA)SubName: Full=2-isopr...   994   0.0  
tr|Q744M9|Q744M9_MYCPA Tax_Id=1770 (leuA)SubName: Full=LeuA;[Myc...   993   0.0  
sp|P96420|LEU1_MYCTU Tax_Id=1773 (leuA)RecName: Full=2-isopropyl...   954   0.0  
tr|C6DNF0|C6DNF0_MYCTK Tax_Id=478434 SubName: Full=2-isopropylma...   954   0.0  
tr|A5U936|A5U936_MYCTA Tax_Id=419947 (leuA)SubName: Full=2-isopr...   954   0.0  
tr|A5WTS8|A5WTS8_MYCTF Tax_Id=336982 SubName: Full=2-isopropylma...   954   0.0  
sp|A0PVE6|LEU1_MYCUA Tax_Id=362242 (leuA)RecName: Full=2-isoprop...   943   0.0  
tr|Q1B282|Q1B282_MYCSS Tax_Id=164756 SubName: Full=2-isopropylma...   941   0.0  
tr|A3Q7A2|A3Q7A2_MYCSJ Tax_Id=164757 SubName: Full=2-isopropylma...   941   0.0  
tr|A1UMW8|A1UMW8_MYCSK Tax_Id=189918 SubName: Full=2-isopropylma...   941   0.0  
tr|A1TGI1|A1TGI1_MYCVP Tax_Id=350058 SubName: Full=2-isopropylma...   941   0.0  
sp|Q7TVV6|LEU1_MYCBO Tax_Id=1765 (leuA)RecName: Full=2-isopropyl...   930   0.0  
tr|C1AIG4|C1AIG4_MYCBT Tax_Id=561275 (leuA)SubName: Full=2-isopr...   930   0.0  
tr|A1KQ42|A1KQ42_MYCBP Tax_Id=410289 (leuA)SubName: Full=2-isopr...   930   0.0  
tr|A4T617|A4T617_MYCGI Tax_Id=350054 SubName: Full=2-isopropylma...   930   0.0  
tr|A0R5Q2|A0R5Q2_MYCS2 Tax_Id=246196 (leuA)SubName: Full=2-isopr...   926   0.0  
tr|Q5Z341|Q5Z341_NOCFA Tax_Id=37329 (leuA)SubName: Full=Putative...   916   0.0  
tr|C1B9P5|C1B9P5_RHOOB Tax_Id=632772 (leuA)SubName: Full=2-isopr...   915   0.0  
tr|B1MFN6|B1MFN6_MYCA9 Tax_Id=561007 SubName: Full=Probable 2-is...   911   0.0  
tr|Q0S8X0|Q0S8X0_RHOSR Tax_Id=101510 (leuA1)SubName: Full=2-isop...   910   0.0  
tr|C0ZN67|C0ZN67_RHOE4 Tax_Id=234621 (leuA)SubName: Full=2-isopr...   905   0.0  
tr|C3JNY6|C3JNY6_RHOER Tax_Id=596309 (leuA)SubName: Full=2-isopr...   904   0.0  
tr|C2AJL2|C2AJL2_TSUPA Tax_Id=521096 SubName: Full=2-isopropylma...   904   0.0  
tr|D0LDG8|D0LDG8_9ACTO Tax_Id=526226 SubName: Full=2-isopropylma...   897   0.0  
tr|C6WF52|C6WF52_ACTMD Tax_Id=446462 SubName: Full=2-isopropylma...   815   0.0  
tr|A4F6E9|A4F6E9_SACEN Tax_Id=405948 (leuA)SubName: Full=2-isopr...   781   0.0  
tr|C5VA14|C5VA14_9CORY Tax_Id=553207 (leuA)SubName: Full=2-isopr...   778   0.0  
tr|Q6NJX5|Q6NJX5_CORDI Tax_Id=1717 (leuA)SubName: Full=2-isoprop...   776   0.0  
tr|C0DZP7|C0DZP7_9CORY Tax_Id=566549 SubName: Full=Putative unch...   775   0.0  
tr|C7MQR7|C7MQR7_SACVD Tax_Id=471857 SubName: Full=2-isopropylma...   774   0.0  
tr|C8NR86|C8NR86_COREF Tax_Id=196164 (leuA)SubName: Full=2-isopr...   774   0.0  
sp|P42455|LEU1_CORGL Tax_Id=1718 (leuA)RecName: Full=2-isopropyl...   773   0.0  
tr|Q4JSM3|Q4JSM3_CORJK Tax_Id=306537 (leuA)SubName: Full=2-isopr...   773   0.0  
tr|C8RV49|C8RV49_CORJE Tax_Id=525262 (leuA)SubName: Full=2-isopr...   773   0.0  
tr|B1VIR4|B1VIR4_CORU7 Tax_Id=504474 SubName: Full=2-isopropylma...   771   0.0  
tr|C4LGL7|C4LGL7_CORK4 Tax_Id=645127 SubName: Full=2-isopropylma...   769   0.0  
sp|A4QAP0|LEU1_CORGB Tax_Id=340322 (leuA)RecName: Full=2-isoprop...   766   0.0  
tr|C8NXJ3|C8NXJ3_9CORY Tax_Id=585529 (leuA)SubName: Full=2-isopr...   757   0.0  
tr|C8X8C8|C8X8C8_NAKMY Tax_Id=479431 SubName: Full=2-isopropylma...   756   0.0  
tr|C3PJR0|C3PJR0_CORA7 Tax_Id=548476 (leuA)SubName: Full=2-isopr...   749   0.0  
sp|Q8FU05|LEU1_COREF Tax_Id=152794 (leuA)RecName: Full=2-isoprop...   744   0.0  
tr|C0WHW2|C0WHW2_9CORY Tax_Id=525260 (leuA)SubName: Full=2-isopr...   743   0.0  
tr|C0XU51|C0XU51_9CORY Tax_Id=525263 (leuA)SubName: Full=2-isopr...   743   0.0  
tr|C2CS87|C2CS87_CORST Tax_Id=525268 (leuA)SubName: Full=2-isopr...   740   0.0  
tr|C2BKT1|C2BKT1_9CORY Tax_Id=525264 (leuA)SubName: Full=2-isopr...   735   0.0  
tr|C6R7K4|C6R7K4_9CORY Tax_Id=553206 (leuA)SubName: Full=2-isopr...   735   0.0  
tr|C1RP27|C1RP27_9CELL Tax_Id=446466 SubName: Full=2-isopropylma...   717   0.0  

>sp|Q9CB76|LEU1_MYCLE Tax_Id=1769 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthetase;[Mycobacterium leprae]
          Length = 607

 Score = 1166 bits (3016), Expect = 0.0
 Identities = 579/607 (95%), Positives = 580/607 (95%)

Query: 1   VASFSESLSQDPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIR 60
           +ASFSESLSQDPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIR
Sbjct: 1   MASFSESLSQDPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIR 60

Query: 61  LVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSA 120
           LVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSA
Sbjct: 61  LVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSA 120

Query: 121 SQTDFDFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQR 180
           SQTDFDFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQR
Sbjct: 121 SQTDFDFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQR 180

Query: 181 RVVFRADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGE 240
           RVVFRADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGE
Sbjct: 181 RVVFRADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGE 240

Query: 241 VIQPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAA 300
           VIQPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAA
Sbjct: 241 VIQPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAA 300

Query: 301 ELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNK 360
           ELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNK
Sbjct: 301 ELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNK 360

Query: 361 LRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRD 420
           LRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKI           ILWQVPYLPIDPRD
Sbjct: 361 LRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIDADAADSDVDDILWQVPYLPIDPRD 420

Query: 421 VGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEM 480
           VGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEM
Sbjct: 421 VGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEM 480

Query: 481 WDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFID 540
           WDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFID
Sbjct: 481 WDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFID 540

Query: 541 ALGHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSA 600
           ALGHVGLQVAVLDYSEH                SVHGHTAWGVGIAPSITTASLRAVVSA
Sbjct: 541 ALGHVGLQVAVLDYSEHAMNAGDDAQAAAYVEASVHGHTAWGVGIAPSITTASLRAVVSA 600

Query: 601 VNRAMPR 607
           VNRAMPR
Sbjct: 601 VNRAMPR 607


>tr|B8ZT16|B8ZT16_MYCLB Tax_Id=561304 (leuA)SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium leprae]
          Length = 607

 Score = 1166 bits (3016), Expect = 0.0
 Identities = 579/607 (95%), Positives = 580/607 (95%)

Query: 1   VASFSESLSQDPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIR 60
           +ASFSESLSQDPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIR
Sbjct: 1   MASFSESLSQDPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIR 60

Query: 61  LVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSA 120
           LVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSA
Sbjct: 61  LVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSA 120

Query: 121 SQTDFDFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQR 180
           SQTDFDFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQR
Sbjct: 121 SQTDFDFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQR 180

Query: 181 RVVFRADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGE 240
           RVVFRADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGE
Sbjct: 181 RVVFRADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGE 240

Query: 241 VIQPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAA 300
           VIQPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAA
Sbjct: 241 VIQPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAA 300

Query: 301 ELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNK 360
           ELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNK
Sbjct: 301 ELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNK 360

Query: 361 LRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRD 420
           LRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKI           ILWQVPYLPIDPRD
Sbjct: 361 LRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIDADAADSDVDDILWQVPYLPIDPRD 420

Query: 421 VGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEM 480
           VGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEM
Sbjct: 421 VGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEM 480

Query: 481 WDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFID 540
           WDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFID
Sbjct: 481 WDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFID 540

Query: 541 ALGHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSA 600
           ALGHVGLQVAVLDYSEH                SVHGHTAWGVGIAPSITTASLRAVVSA
Sbjct: 541 ALGHVGLQVAVLDYSEHAMNAGDDAQAAAYVEASVHGHTAWGVGIAPSITTASLRAVVSA 600

Query: 601 VNRAMPR 607
           VNRAMPR
Sbjct: 601 VNRAMPR 607


>tr|B2HKD3|B2HKD3_MYCMM Tax_Id=216594 (leuA)SubName:
           Full=2-isopropylmalate synthase LeuA;[Mycobacterium
           marinum]
          Length = 606

 Score =  995 bits (2573), Expect = 0.0
 Identities = 502/600 (83%), Positives = 529/600 (88%), Gaps = 4/600 (0%)

Query: 9   SQDPA-DAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWP 67
           SQ P  DA+ SA +I KP GPPSPGQP WNPQRA+SMPV RYRPFA+EVE IR+ DRTWP
Sbjct: 5   SQAPGPDAFTSARTIVKPAGPPSPGQPVWNPQRASSMPVNRYRPFAEEVEHIRVTDRTWP 64

Query: 68  DRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 127
           DRVID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 128 VREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRAD 187
           VREIIT+G IPDDVTIQVLTQCRPELIERTFEAC  AS+VIVHFYNSTSILQRRVVFRAD
Sbjct: 125 VREIITEGAIPDDVTIQVLTQCRPELIERTFEACAGASKVIVHFYNSTSILQRRVVFRAD 184

Query: 188 QATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPD 247
           +A V+AIAT+GAR+CVEEA KYP T WRFEYSPESYTGTELEYAKQVCDAV EVIQPTP+
Sbjct: 185 RAAVQAIATEGARRCVEEAAKYPDTQWRFEYSPESYTGTELEYAKQVCDAVAEVIQPTPE 244

Query: 248 NPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAG 307
           NPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG+ AG
Sbjct: 245 NPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 308 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERH 367
           ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L V ERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVPERH 364

Query: 368 PYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEA 427
           PYGGDLVYTAFSGSHQDAINKGLD MK            +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKFDADAADSDMDDMLWQVPYLPIDPKDVGRTYEA 424

Query: 428 VIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWDVF 484
           VIRVNSQSGKGGVAYIMKADHGL LPRRLQIEFSRAIQ+I+E   GEGGE++P EMWD F
Sbjct: 425 VIRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSRAIQEIAEGSAGEGGEVSPKEMWDAF 484

Query: 485 FEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGH 544
            EEYL+PV+PLERIKQRV AAEEDGG+TSI ATVKI+G+ETEISG GNGPLAAF+ ALG 
Sbjct: 485 AEEYLAPVRPLERIKQRVIAAEEDGGTTSIDATVKIDGKETEISGSGNGPLAAFVHALGS 544

Query: 545 VGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           VG  VAVLDYSEH                SV G T WGVGIAPSITTASLRAVVSA+NRA
Sbjct: 545 VGFDVAVLDYSEHAMSAGDDAQAAAYVEASVAGKTVWGVGIAPSITTASLRAVVSAINRA 604


>tr|A0Q9T9|A0Q9T9_MYCA1 Tax_Id=243243 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium avium]
          Length = 599

 Score =  994 bits (2570), Expect = 0.0
 Identities = 490/591 (82%), Positives = 522/591 (88%)

Query: 14  DAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVIDC 73
           DA+ S+ SI KP GPP PGQP WNPQR +SMPV RYRPFA+EVEPIRL DRTWPD+VID 
Sbjct: 6   DAFSSSRSIVKPAGPPGPGQPAWNPQRGSSMPVNRYRPFAEEVEPIRLPDRTWPDKVIDR 65

Query: 74  APLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIT 133
           APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI+T
Sbjct: 66  APLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIVT 125

Query: 134 DGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVKA 193
           +G IPDDVTIQVLTQCRPELIERTF AC+ A + IVHFYNSTSILQRRVVFRAD+A V+ 
Sbjct: 126 EGAIPDDVTIQVLTQCRPELIERTFAACQGAPQAIVHFYNSTSILQRRVVFRADRAAVQE 185

Query: 194 IATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIFN 253
           IA  GARKCVEEA KYP T WRFEYSPESYTGTELEYAKQVCDAVGE+I+PTP+NPIIFN
Sbjct: 186 IAVAGARKCVEEAAKYPETRWRFEYSPESYTGTELEYAKQVCDAVGEIIRPTPENPIIFN 245

Query: 254 LPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIEG 313
           LPATVEMATPNVYADSIEWMSRNLA R+SVILSLHPHNDRGTAVAAAELGY AGADRIEG
Sbjct: 246 LPATVEMATPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGYAAGADRIEG 305

Query: 314 CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGDL 373
           CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYGGDL
Sbjct: 306 CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL 365

Query: 374 VYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVNS 433
           VYTAFSGSHQDAINKGLDQM+I           +LWQVPYLPIDP+DVGRTYEAVIRVNS
Sbjct: 366 VYTAFSGSHQDAINKGLDQMEIDADAADTDVEDMLWQVPYLPIDPKDVGRTYEAVIRVNS 425

Query: 434 QSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPVQ 493
           QSGKGGVAYIMKADHGL LPRRLQIEFS+ IQKISEGEGGE++P EMWD FFEEYL+PV 
Sbjct: 426 QSGKGGVAYIMKADHGLALPRRLQIEFSQVIQKISEGEGGEVSPKEMWDAFFEEYLAPVW 485

Query: 494 PLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVLD 553
           PLER+KQRV+A++ED G TSI+ATVKINGE+TEI+G GNGPLAAF+ AL  VG  VAVLD
Sbjct: 486 PLERVKQRVDASDEDSGVTSISATVKINGEQTEINGTGNGPLAAFVHALAGVGFDVAVLD 545

Query: 554 YSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           YSEH                SV+G T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 546 YSEHAMSSGDDAQAAAYVEASVNGRTVWGVGIAPSITTASLRAVVSAVNRA 596


>tr|Q744M9|Q744M9_MYCPA Tax_Id=1770 (leuA)SubName:
           Full=LeuA;[Mycobacterium paratuberculosis]
          Length = 614

 Score =  993 bits (2567), Expect = 0.0
 Identities = 491/591 (83%), Positives = 521/591 (88%)

Query: 14  DAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVIDC 73
           DA+ S+ SI KP GPP PGQP WNPQR +SMPV RYRPFA+EVEPIRL DRTWPD+VID 
Sbjct: 21  DAFSSSRSIVKPAGPPGPGQPAWNPQRGSSMPVNRYRPFAEEVEPIRLPDRTWPDKVIDR 80

Query: 74  APLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIT 133
           APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIT
Sbjct: 81  APLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIT 140

Query: 134 DGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVKA 193
           +G IPDDVTIQVLTQCRPELIERTF AC+ A + IVHFYNSTSILQRRVVFRAD+A V+ 
Sbjct: 141 EGAIPDDVTIQVLTQCRPELIERTFAACQGAPQAIVHFYNSTSILQRRVVFRADRAAVQE 200

Query: 194 IATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIFN 253
           IA  GARKCVEEA KYP T WRFEYSPESYTGTELEYAKQVCDAVGE+I+PT +NPIIFN
Sbjct: 201 IAVAGARKCVEEAAKYPETQWRFEYSPESYTGTELEYAKQVCDAVGEIIRPTTENPIIFN 260

Query: 254 LPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIEG 313
           LPATVEMATPNVYADSIEWMSRNLA R+SVILSLHPHNDRGTAVAAAELGY AGADRIEG
Sbjct: 261 LPATVEMATPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGYAAGADRIEG 320

Query: 314 CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGDL 373
           CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYGGDL
Sbjct: 321 CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL 380

Query: 374 VYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVNS 433
           VYTAFSGSHQDAINKGLDQMKI           +LWQVPYLPIDP+DVGRTYEAVIRVNS
Sbjct: 381 VYTAFSGSHQDAINKGLDQMKIDADAADTDVEDMLWQVPYLPIDPKDVGRTYEAVIRVNS 440

Query: 434 QSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPVQ 493
           QSGKGGVAYIMKADHGL LPRRLQIEFS+ IQKISEGEGGE++P EMWD FFEEYL+PV 
Sbjct: 441 QSGKGGVAYIMKADHGLALPRRLQIEFSQVIQKISEGEGGEVSPKEMWDAFFEEYLAPVW 500

Query: 494 PLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVLD 553
           PLER+KQRV+A++ED G TSI+ATVKINGE+TEI+G GNGPLAAF+ AL  VG  VAVLD
Sbjct: 501 PLERVKQRVDASDEDSGVTSISATVKINGEQTEINGTGNGPLAAFVHALAGVGFDVAVLD 560

Query: 554 YSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           YSEH                SV+G T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 561 YSEHAMSSGDDAQAAAYVEASVNGRTVWGVGIAPSITTASLRAVVSAVNRA 611


>sp|P96420|LEU1_MYCTU Tax_Id=1773 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthetase;[Mycobacterium tuberculosis]
          Length = 644

 Score =  954 bits (2465), Expect = 0.0
 Identities = 491/640 (76%), Positives = 518/640 (80%), Gaps = 45/640 (7%)

Query: 9   SQDPADAYKS---APSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRT 65
           S+ P DAY     A +I KP GPP  GQP WNPQRA+SMPV RYRPFA+EVEPIRL +RT
Sbjct: 4   SESP-DAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRT 62

Query: 66  WPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDF 125
           WPDRVID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 63  WPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 122

Query: 126 DFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFR 185
           DFVREII  G IPDDVTIQVLTQCRPELIERTF+AC  A R IVHFYNSTSILQRRVVFR
Sbjct: 123 DFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFR 182

Query: 186 ADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPT 245
           A++A V+AIATDGARKCVE+A KYPGT WRFEYSPESYTGTELEYAKQVCDAVGEVI PT
Sbjct: 183 ANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPT 242

Query: 246 PDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYH 305
           P+ PIIFNLPATVEM TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG+ 
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFA 302

Query: 306 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHE 365
           AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHE
Sbjct: 303 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 362

Query: 366 RHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           RHPYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDPRDVGRTY
Sbjct: 363 RHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTY 422

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWD 482
           EAVIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFS+ IQKI+E   GEGGE++P EMWD
Sbjct: 423 EAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWD 482

Query: 483 VFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDAL 542
            F EEYL+PV+PLERI+Q V+AA++DGG+TSI ATVKING ETEISG GNGPLAAF+ AL
Sbjct: 483 AFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHAL 542

Query: 543 GHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXS---------------------------- 574
             VG  VAVLDY EH                S                            
Sbjct: 543 ADVGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQP 602

Query: 575 ----------VHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
                     V   T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 603 GEAGRHASDPVTSKTVWGVGIAPSITTASLRAVVSAVNRA 642


>tr|C6DNF0|C6DNF0_MYCTK Tax_Id=478434 SubName:
           Full=2-isopropylmalate synthase leuA;[Mycobacterium
           tuberculosis]
          Length = 644

 Score =  954 bits (2465), Expect = 0.0
 Identities = 491/640 (76%), Positives = 518/640 (80%), Gaps = 45/640 (7%)

Query: 9   SQDPADAYKS---APSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRT 65
           S+ P DAY     A +I KP GPP  GQP WNPQRA+SMPV RYRPFA+EVEPIRL +RT
Sbjct: 4   SESP-DAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRT 62

Query: 66  WPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDF 125
           WPDRVID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 63  WPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 122

Query: 126 DFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFR 185
           DFVREII  G IPDDVTIQVLTQCRPELIERTF+AC  A R IVHFYNSTSILQRRVVFR
Sbjct: 123 DFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFR 182

Query: 186 ADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPT 245
           A++A V+AIATDGARKCVE+A KYPGT WRFEYSPESYTGTELEYAKQVCDAVGEVI PT
Sbjct: 183 ANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPT 242

Query: 246 PDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYH 305
           P+ PIIFNLPATVEM TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG+ 
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFA 302

Query: 306 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHE 365
           AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHE
Sbjct: 303 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 362

Query: 366 RHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           RHPYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDPRDVGRTY
Sbjct: 363 RHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTY 422

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWD 482
           EAVIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFS+ IQKI+E   GEGGE++P EMWD
Sbjct: 423 EAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWD 482

Query: 483 VFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDAL 542
            F EEYL+PV+PLERI+Q V+AA++DGG+TSI ATVKING ETEISG GNGPLAAF+ AL
Sbjct: 483 AFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHAL 542

Query: 543 GHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXS---------------------------- 574
             VG  VAVLDY EH                S                            
Sbjct: 543 ADVGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQP 602

Query: 575 ----------VHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
                     V   T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 603 GEAGRHASDPVTSKTVWGVGIAPSITTASLRAVVSAVNRA 642


>tr|A5U936|A5U936_MYCTA Tax_Id=419947 (leuA)SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           tuberculosis]
          Length = 644

 Score =  954 bits (2465), Expect = 0.0
 Identities = 491/640 (76%), Positives = 518/640 (80%), Gaps = 45/640 (7%)

Query: 9   SQDPADAYKS---APSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRT 65
           S+ P DAY     A +I KP GPP  GQP WNPQRA+SMPV RYRPFA+EVEPIRL +RT
Sbjct: 4   SESP-DAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRT 62

Query: 66  WPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDF 125
           WPDRVID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 63  WPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 122

Query: 126 DFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFR 185
           DFVREII  G IPDDVTIQVLTQCRPELIERTF+AC  A R IVHFYNSTSILQRRVVFR
Sbjct: 123 DFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFR 182

Query: 186 ADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPT 245
           A++A V+AIATDGARKCVE+A KYPGT WRFEYSPESYTGTELEYAKQVCDAVGEVI PT
Sbjct: 183 ANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPT 242

Query: 246 PDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYH 305
           P+ PIIFNLPATVEM TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG+ 
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFA 302

Query: 306 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHE 365
           AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHE
Sbjct: 303 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 362

Query: 366 RHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           RHPYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDPRDVGRTY
Sbjct: 363 RHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTY 422

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWD 482
           EAVIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFS+ IQKI+E   GEGGE++P EMWD
Sbjct: 423 EAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWD 482

Query: 483 VFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDAL 542
            F EEYL+PV+PLERI+Q V+AA++DGG+TSI ATVKING ETEISG GNGPLAAF+ AL
Sbjct: 483 AFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHAL 542

Query: 543 GHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXS---------------------------- 574
             VG  VAVLDY EH                S                            
Sbjct: 543 ADVGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQP 602

Query: 575 ----------VHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
                     V   T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 603 GEAGRHASDPVTSKTVWGVGIAPSITTASLRAVVSAVNRA 642


>tr|A5WTS8|A5WTS8_MYCTF Tax_Id=336982 SubName:
           Full=2-isopropylmalate synthase leuA;[Mycobacterium
           tuberculosis]
          Length = 644

 Score =  954 bits (2465), Expect = 0.0
 Identities = 491/640 (76%), Positives = 518/640 (80%), Gaps = 45/640 (7%)

Query: 9   SQDPADAYKS---APSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRT 65
           S+ P DAY     A +I KP GPP  GQP WNPQRA+SMPV RYRPFA+EVEPIRL +RT
Sbjct: 4   SESP-DAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRT 62

Query: 66  WPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDF 125
           WPDRVID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 63  WPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 122

Query: 126 DFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFR 185
           DFVREII  G IPDDVTIQVLTQCRPELIERTF+AC  A R IVHFYNSTSILQRRVVFR
Sbjct: 123 DFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFR 182

Query: 186 ADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPT 245
           A++A V+AIATDGARKCVE+A KYPGT WRFEYSPESYTGTELEYAKQVCDAVGEVI PT
Sbjct: 183 ANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPT 242

Query: 246 PDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYH 305
           P+ PIIFNLPATVEM TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG+ 
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFA 302

Query: 306 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHE 365
           AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHE
Sbjct: 303 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 362

Query: 366 RHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           RHPYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDPRDVGRTY
Sbjct: 363 RHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTY 422

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWD 482
           EAVIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFS+ IQKI+E   GEGGE++P EMWD
Sbjct: 423 EAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWD 482

Query: 483 VFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDAL 542
            F EEYL+PV+PLERI+Q V+AA++DGG+TSI ATVKING ETEISG GNGPLAAF+ AL
Sbjct: 483 AFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHAL 542

Query: 543 GHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXS---------------------------- 574
             VG  VAVLDY EH                S                            
Sbjct: 543 ADVGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQP 602

Query: 575 ----------VHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
                     V   T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 603 GEAGRHASDPVTSKTVWGVGIAPSITTASLRAVVSAVNRA 642


>sp|A0PVE6|LEU1_MYCUA Tax_Id=362242 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthetase;[Mycobacterium ulcerans]
          Length = 566

 Score =  943 bits (2437), Expect = 0.0
 Identities = 475/564 (84%), Positives = 499/564 (88%), Gaps = 3/564 (0%)

Query: 44  MPVFRYRPFAKEVEPIRLVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFD 103
           MPV RYRPFA+EVE IR+ DRTWPDRVID APLWCAVDLRDGNQALIDPMSP  KRRMFD
Sbjct: 1   MPVNRYRPFAEEVEHIRVTDRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFD 60

Query: 104 LLVRMGYKEIEVGFPSASQTDFDFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACEN 163
           LLVRMGYKEIEVGFPSASQTDFDFVREIIT+G IPDDVTIQVLTQCRPELIERTFEAC  
Sbjct: 61  LLVRMGYKEIEVGFPSASQTDFDFVREIITEGAIPDDVTIQVLTQCRPELIERTFEACAG 120

Query: 164 ASRVIVHFYNSTSILQRRVVFRADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESY 223
           AS+VIVHFYNSTSILQRRVVFRAD+A V+AIATDGAR+CVEEA KYP T WRFEYSPESY
Sbjct: 121 ASKVIVHFYNSTSILQRRVVFRADRAAVEAIATDGARRCVEEAAKYPDTQWRFEYSPESY 180

Query: 224 TGTELEYAKQVCDAVGEVIQPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESV 283
           TGTELEYAKQVCDAV EVIQPTP+NPIIFNLPATVEMATPNVYADSIEWMSRNLANRESV
Sbjct: 181 TGTELEYAKQVCDAVAEVIQPTPENPIIFNLPATVEMATPNVYADSIEWMSRNLANRESV 240

Query: 284 ILSLHPHNDRGTAVAAAELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQI 343
           ILSLHPHNDRGTAVAAAELG+ AGADRIEGCLFGNGERTGNVCL TLGLNLFSRGVDPQI
Sbjct: 241 ILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLATLGLNLFSRGVDPQI 300

Query: 344 DFSNIDEIRRTVEYCNKLRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXX 403
           DFSNIDEIRRTVEYCN+L V ERHPYGGDLVYTAFSGSHQDAINKGLD M+         
Sbjct: 301 DFSNIDEIRRTVEYCNQLPVPERHPYGGDLVYTAFSGSHQDAINKGLDAMEFDADAADSD 360

Query: 404 XXXILWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRA 463
              +LWQVPYLPIDP+DVGRTYEAVIRVNSQSGKGGVAYIMKADHGL LPRRLQIEFSRA
Sbjct: 361 MDDMLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSRA 420

Query: 464 IQKISE---GEGGEITPTEMWDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKI 520
           IQ+I+E   GEGGE++P EMWD F EEYL+PV+PLERIKQRV AAEEDGG+TSI ATVKI
Sbjct: 421 IQEIAEGSAGEGGEVSPKEMWDAFAEEYLAPVRPLERIKQRVIAAEEDGGTTSIDATVKI 480

Query: 521 NGEETEISGVGNGPLAAFIDALGHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTA 580
           +G+E EISG GNGPLAAF+ ALG VG  VAVLDYSEH                SV G T 
Sbjct: 481 DGKEAEISGSGNGPLAAFVHALGTVGFDVAVLDYSEHAMSAGDDAQAAAYVEASVAGKTV 540

Query: 581 WGVGIAPSITTASLRAVVSAVNRA 604
           WGVGIAPSITTASLRAVVSA+NRA
Sbjct: 541 WGVGIAPSITTASLRAVVSAINRA 564


>tr|Q1B282|Q1B282_MYCSS Tax_Id=164756 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium sp.]
          Length = 601

 Score =  941 bits (2433), Expect = 0.0
 Identities = 462/594 (77%), Positives = 507/594 (85%)

Query: 11  DPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           +  DA+ S  +IT P GPP PGQP WN QRA++MPV RYR FA+EVEP+ L DRTWPD+V
Sbjct: 5   ESTDAFSSVRAITTPSGPPHPGQPAWNTQRASAMPVSRYRSFAEEVEPVTLPDRTWPDKV 64

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           +D AP+WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE
Sbjct: 65  VDTAPMWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 124

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II  G IPDDVTIQVLTQCRPELI RTFEAC+ A R IVHFYNSTSILQRRVVFRAD+  
Sbjct: 125 IIEQGAIPDDVTIQVLTQCRPELITRTFEACKGAPRAIVHFYNSTSILQRRVVFRADREA 184

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           VK IA DGAR CVEEA K+P T WRFEYSPESYTGTELEYA  VC+AV ++++PTP+ P+
Sbjct: 185 VKQIAVDGARMCVEEAAKHPDTLWRFEYSPESYTGTELEYAVDVCNAVADIVKPTPEVPL 244

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEMATPNVYADSIEWM+R+L+ R+S+ILSLHPHNDRGTAVAAAELGY AGADR
Sbjct: 245 IVNLPATVEMATPNVYADSIEWMNRHLSPRDSIILSLHPHNDRGTAVAAAELGYQAGADR 304

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYG
Sbjct: 305 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 364

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIR 430
           GDLVYTAFSGSHQDAINKGLD MK+           ILWQVPYLPIDP+DVGRTYEAVIR
Sbjct: 365 GDLVYTAFSGSHQDAINKGLDAMKVAADEADSDVDDILWQVPYLPIDPKDVGRTYEAVIR 424

Query: 431 VNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLS 490
           VNSQSGKGGVAYIMKADHGL LPRRLQIEFS+AIQKI++GEGGE++P EMWDVF EEYLS
Sbjct: 425 VNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAIQKITDGEGGEVSPKEMWDVFAEEYLS 484

Query: 491 PVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVA 550
           PV+PLER++Q+V+AAE DGG+ +I A VK++G E EI G GNGPLAAF DALG +G  ++
Sbjct: 485 PVRPLERMRQKVDAAEVDGGTDTITAVVKVDGVEREIVGAGNGPLAAFCDALGAIGFDIS 544

Query: 551 VLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           VLDYSEH                SV G T WGVGIA SITTASLRAVVSAVNRA
Sbjct: 545 VLDYSEHALSAGEEAQAAAYVEASVGGKTVWGVGIATSITTASLRAVVSAVNRA 598


>tr|A3Q7A2|A3Q7A2_MYCSJ Tax_Id=164757 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium sp.]
          Length = 601

 Score =  941 bits (2433), Expect = 0.0
 Identities = 462/594 (77%), Positives = 507/594 (85%)

Query: 11  DPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           +  DA+ S  +IT P GPP PGQP WN QRA++MPV RYR FA+EVEP+ L DRTWPD+V
Sbjct: 5   ESTDAFSSVRAITTPSGPPHPGQPAWNTQRASAMPVSRYRSFAEEVEPVTLPDRTWPDKV 64

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           +D AP+WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE
Sbjct: 65  VDTAPMWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 124

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II  G IPDDVTIQVLTQCRPELI RTFEAC+ A R IVHFYNSTSILQRRVVFRAD+  
Sbjct: 125 IIEQGAIPDDVTIQVLTQCRPELITRTFEACKGAPRAIVHFYNSTSILQRRVVFRADREA 184

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           VK IA DGAR CVEEA K+P T WRFEYSPESYTGTELEYA  VC+AV ++++PTP+ P+
Sbjct: 185 VKQIAVDGARMCVEEAAKHPDTLWRFEYSPESYTGTELEYAVDVCNAVADIVKPTPEVPL 244

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEMATPNVYADSIEWM+R+L+ R+S+ILSLHPHNDRGTAVAAAELGY AGADR
Sbjct: 245 IVNLPATVEMATPNVYADSIEWMNRHLSPRDSIILSLHPHNDRGTAVAAAELGYQAGADR 304

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYG
Sbjct: 305 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 364

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIR 430
           GDLVYTAFSGSHQDAINKGLD MK+           ILWQVPYLPIDP+DVGRTYEAVIR
Sbjct: 365 GDLVYTAFSGSHQDAINKGLDAMKVAADEADSDVDDILWQVPYLPIDPKDVGRTYEAVIR 424

Query: 431 VNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLS 490
           VNSQSGKGGVAYIMKADHGL LPRRLQIEFS+AIQKI++GEGGE++P EMWDVF EEYLS
Sbjct: 425 VNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAIQKITDGEGGEVSPKEMWDVFAEEYLS 484

Query: 491 PVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVA 550
           PV+PLER++Q+V+AAE DGG+ +I A VK++G E EI G GNGPLAAF DALG +G  ++
Sbjct: 485 PVRPLERMRQKVDAAEVDGGTDTITAVVKVDGVEREIVGAGNGPLAAFCDALGAIGFDIS 544

Query: 551 VLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           VLDYSEH                SV G T WGVGIA SITTASLRAVVSAVNRA
Sbjct: 545 VLDYSEHALSAGEEAQAAAYVEASVGGKTVWGVGIATSITTASLRAVVSAVNRA 598


>tr|A1UMW8|A1UMW8_MYCSK Tax_Id=189918 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium sp.]
          Length = 601

 Score =  941 bits (2433), Expect = 0.0
 Identities = 462/594 (77%), Positives = 507/594 (85%)

Query: 11  DPADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           +  DA+ S  +IT P GPP PGQP WN QRA++MPV RYR FA+EVEP+ L DRTWPD+V
Sbjct: 5   ESTDAFSSVRAITTPSGPPHPGQPAWNTQRASAMPVSRYRSFAEEVEPVTLPDRTWPDKV 64

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           +D AP+WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE
Sbjct: 65  VDTAPMWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 124

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II  G IPDDVTIQVLTQCRPELI RTFEAC+ A R IVHFYNSTSILQRRVVFRAD+  
Sbjct: 125 IIEQGAIPDDVTIQVLTQCRPELITRTFEACKGAPRAIVHFYNSTSILQRRVVFRADREA 184

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           VK IA DGAR CVEEA K+P T WRFEYSPESYTGTELEYA  VC+AV ++++PTP+ P+
Sbjct: 185 VKQIAVDGARMCVEEAAKHPDTLWRFEYSPESYTGTELEYAVDVCNAVADIVKPTPEVPL 244

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEMATPNVYADSIEWM+R+L+ R+S+ILSLHPHNDRGTAVAAAELGY AGADR
Sbjct: 245 IVNLPATVEMATPNVYADSIEWMNRHLSPRDSIILSLHPHNDRGTAVAAAELGYQAGADR 304

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYG
Sbjct: 305 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 364

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIR 430
           GDLVYTAFSGSHQDAINKGLD MK+           ILWQVPYLPIDP+DVGRTYEAVIR
Sbjct: 365 GDLVYTAFSGSHQDAINKGLDAMKVAADEADSDVDDILWQVPYLPIDPKDVGRTYEAVIR 424

Query: 431 VNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLS 490
           VNSQSGKGGVAYIMKADHGL LPRRLQIEFS+AIQKI++GEGGE++P EMWDVF EEYLS
Sbjct: 425 VNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAIQKITDGEGGEVSPKEMWDVFAEEYLS 484

Query: 491 PVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVA 550
           PV+PLER++Q+V+AAE DGG+ +I A VK++G E EI G GNGPLAAF DALG +G  ++
Sbjct: 485 PVRPLERMRQKVDAAEVDGGTDTITAVVKVDGVEREIVGAGNGPLAAFCDALGAIGFDIS 544

Query: 551 VLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           VLDYSEH                SV G T WGVGIA SITTASLRAVVSAVNRA
Sbjct: 545 VLDYSEHALSAGEEAQAAAYVEASVGGKTVWGVGIATSITTASLRAVVSAVNRA 598


>tr|A1TGI1|A1TGI1_MYCVP Tax_Id=350058 SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           vanbaalenii]
          Length = 612

 Score =  941 bits (2433), Expect = 0.0
 Identities = 466/596 (78%), Positives = 505/596 (84%), Gaps = 3/596 (0%)

Query: 13  ADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVE---PIRLVDRTWPDR 69
           ADAY S  +IT P GPP+PGQP WN QR +SMPV RYR FA EV    P    DRTWPD+
Sbjct: 9   ADAYSSVRTITTPAGPPNPGQPSWNTQRGSSMPVSRYRNFAAEVPGGAPAAPFDRTWPDK 68

Query: 70  VIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVR 129
           VID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLV+MGYKEIEVGFPSASQTD+DFVR
Sbjct: 69  VIDTAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVKMGYKEIEVGFPSASQTDYDFVR 128

Query: 130 EIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQA 189
           EII  G IPDDVTIQVLTQCR ELIERTFEAC+ A  VIVHFYNSTSILQRRVVFRAD+ 
Sbjct: 129 EIIEQGAIPDDVTIQVLTQCRDELIERTFEACDGAPNVIVHFYNSTSILQRRVVFRADRD 188

Query: 190 TVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNP 249
            +K IATDGARKC+EEA K+PGT WR+EYSPESYTGTELEYA  VC+AV EVI+PTPD P
Sbjct: 189 EIKKIATDGARKCLEEAGKHPGTRWRYEYSPESYTGTELEYALDVCNAVSEVIEPTPDWP 248

Query: 250 IIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGAD 309
           +I NLPATVEMATPNVYADSIEWMSRNLA R S+ILSLHPHNDRGTAVAAAELGY AGAD
Sbjct: 249 LIVNLPATVEMATPNVYADSIEWMSRNLARRGSIILSLHPHNDRGTAVAAAELGYQAGAD 308

Query: 310 RIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPY 369
           RIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPY
Sbjct: 309 RIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLGVHERHPY 368

Query: 370 GGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVI 429
           GGDLVYTAFSGSHQDAINKGLD MKI           I+WQVPYLPIDP+DVGRTYEAVI
Sbjct: 369 GGDLVYTAFSGSHQDAINKGLDAMKISADEQDSDVDDIVWQVPYLPIDPKDVGRTYEAVI 428

Query: 430 RVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYL 489
           RVNSQSGKGGVAYIMKADHGL LPRRLQIEFS+AIQ+I++GEGGE++P EMWD F++EYL
Sbjct: 429 RVNSQSGKGGVAYIMKADHGLALPRRLQIEFSQAIQQITDGEGGEVSPKEMWDAFYDEYL 488

Query: 490 SPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQV 549
           +P+ PLERI+Q+V+A+E DGG+ +I A VK+NGEE EI G GNGPLAAF+DA+G VG  V
Sbjct: 489 APITPLERIRQKVDASEVDGGTDTITAVVKVNGEEHEIVGAGNGPLAAFVDAIGAVGFHV 548

Query: 550 AVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRAM 605
            VLDYSEH                 + G T WGVGIA SITTASLRAVVSAVNRAM
Sbjct: 549 NVLDYSEHAMSAGEEAAAAAYVEAEIDGKTVWGVGIATSITTASLRAVVSAVNRAM 604


>sp|Q7TVV6|LEU1_MYCBO Tax_Id=1765 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthetase;[Mycobacterium bovis]
          Length = 701

 Score =  930 bits (2404), Expect = 0.0
 Identities = 464/555 (83%), Positives = 491/555 (88%), Gaps = 7/555 (1%)

Query: 9   SQDPADAYKS---APSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRT 65
           S+ P DAY     A +I KP GPP  GQP WNPQRA+SMPV RYRPFA+EVEPIRL +RT
Sbjct: 4   SESP-DAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRT 62

Query: 66  WPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDF 125
           WPDRVID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 63  WPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 122

Query: 126 DFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFR 185
           DFVREII  G IPDDVTIQVLTQCRPELIERTF+AC  A R IVHFYNSTSILQRRVVFR
Sbjct: 123 DFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAHRAIVHFYNSTSILQRRVVFR 182

Query: 186 ADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPT 245
           A++A V+AIATDGARKCVE+A KYPGT WRFEYSPESYTGTELEYAKQVCDAVGEVI PT
Sbjct: 183 ANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPT 242

Query: 246 PDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYH 305
           P+ PIIFNLPATVEM TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG+ 
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFA 302

Query: 306 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHE 365
           AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHE
Sbjct: 303 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 362

Query: 366 RHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           RHPYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDPRDVGRTY
Sbjct: 363 RHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTY 422

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWD 482
           EAVIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFS+ IQKI+E   GEGGE++P EMWD
Sbjct: 423 EAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWD 482

Query: 483 VFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDAL 542
            F EEYL+PV+PLERI+Q V+AA++DGG+TSI ATVKING ETEISG GNGPLAAF+ AL
Sbjct: 483 AFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHAL 542

Query: 543 GHVGLQVAVLDYSEH 557
             VG  VAVLDY EH
Sbjct: 543 ADVGFDVAVLDYYEH 557



 Score = 51.6 bits (122), Expect = 3e-04
 Identities = 26/30 (86%), Positives = 26/30 (86%)

Query: 575 VHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           V   T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 670 VTSKTVWGVGIAPSITTASLRAVVSAVNRA 699


>tr|C1AIG4|C1AIG4_MYCBT Tax_Id=561275 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium bovis]
          Length = 815

 Score =  930 bits (2404), Expect = 0.0
 Identities = 464/555 (83%), Positives = 491/555 (88%), Gaps = 7/555 (1%)

Query: 9   SQDPADAYKS---APSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRT 65
           S+ P DAY     A +I KP GPP  GQP WNPQRA+SMPV RYRPFA+EVEPIRL +RT
Sbjct: 4   SESP-DAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRT 62

Query: 66  WPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDF 125
           WPDRVID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 63  WPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 122

Query: 126 DFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFR 185
           DFVREII  G IPDDVTIQVLTQCRPELIERTF+AC  A R IVHFYNSTSILQRRVVFR
Sbjct: 123 DFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAHRAIVHFYNSTSILQRRVVFR 182

Query: 186 ADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPT 245
           A++A V+AIATDGARKCVE+A KYPGT WRFEYSPESYTGTELEYAKQVCDAVGEVI PT
Sbjct: 183 ANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPT 242

Query: 246 PDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYH 305
           P+ PIIFNLPATVEM TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG+ 
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFA 302

Query: 306 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHE 365
           AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHE
Sbjct: 303 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 362

Query: 366 RHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           RHPYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDPRDVGRTY
Sbjct: 363 RHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTY 422

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWD 482
           EAVIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFS+ IQKI+E   GEGGE++P EMWD
Sbjct: 423 EAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWD 482

Query: 483 VFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDAL 542
            F EEYL+PV+PLERI+Q V+AA++DGG+TSI ATVKING ETEISG GNGPLAAF+ AL
Sbjct: 483 AFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHAL 542

Query: 543 GHVGLQVAVLDYSEH 557
             VG  VAVLDY EH
Sbjct: 543 ADVGFDVAVLDYYEH 557



 Score = 51.6 bits (122), Expect = 3e-04
 Identities = 26/30 (86%), Positives = 26/30 (86%)

Query: 575 VHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           V   T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 784 VTSKTVWGVGIAPSITTASLRAVVSAVNRA 813


>tr|A1KQ42|A1KQ42_MYCBP Tax_Id=410289 (leuA)SubName:
           Full=2-isopropylmalate synthase leuA;
           EC=2.3.3.13;[Mycobacterium bovis]
          Length = 834

 Score =  930 bits (2404), Expect = 0.0
 Identities = 464/555 (83%), Positives = 491/555 (88%), Gaps = 7/555 (1%)

Query: 9   SQDPADAYKS---APSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRT 65
           S+ P DAY     A +I KP GPP  GQP WNPQRA+SMPV RYRPFA+EVEPIRL +RT
Sbjct: 4   SESP-DAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRT 62

Query: 66  WPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDF 125
           WPDRVID APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 63  WPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 122

Query: 126 DFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFR 185
           DFVREII  G IPDDVTIQVLTQCRPELIERTF+AC  A R IVHFYNSTSILQRRVVFR
Sbjct: 123 DFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAHRAIVHFYNSTSILQRRVVFR 182

Query: 186 ADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPT 245
           A++A V+AIATDGARKCVE+A KYPGT WRFEYSPESYTGTELEYAKQVCDAVGEVI PT
Sbjct: 183 ANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPT 242

Query: 246 PDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYH 305
           P+ PIIFNLPATVEM TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELG+ 
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFA 302

Query: 306 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHE 365
           AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L VHE
Sbjct: 303 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 362

Query: 366 RHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           RHPYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDPRDVGRTY
Sbjct: 363 RHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTY 422

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISE---GEGGEITPTEMWD 482
           EAVIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFS+ IQKI+E   GEGGE++P EMWD
Sbjct: 423 EAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWD 482

Query: 483 VFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDAL 542
            F EEYL+PV+PLERI+Q V+AA++DGG+TSI ATVKING ETEISG GNGPLAAF+ AL
Sbjct: 483 AFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHAL 542

Query: 543 GHVGLQVAVLDYSEH 557
             VG  VAVLDY EH
Sbjct: 543 ADVGFDVAVLDYYEH 557



 Score = 51.6 bits (122), Expect = 3e-04
 Identities = 26/30 (86%), Positives = 26/30 (86%)

Query: 575 VHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           V   T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 803 VTSKTVWGVGIAPSITTASLRAVVSAVNRA 832


>tr|A4T617|A4T617_MYCGI Tax_Id=350054 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium gilvum]
          Length = 606

 Score =  930 bits (2403), Expect = 0.0
 Identities = 461/592 (77%), Positives = 499/592 (84%)

Query: 13  ADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72
           ADA+ S  +I  P G P+PGQP WN QRA+SMPV RYR F  EVEPIRL DRTWP++ I 
Sbjct: 9   ADAFSSVRTIVTPAGKPNPGQPSWNTQRASSMPVNRYRSFDDEVEPIRLPDRTWPEKAIT 68

Query: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132
            AP+W AVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII
Sbjct: 69  TAPMWAAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 128

Query: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192
             G IPDDVTIQVLTQCRPELIERTF AC+ A R IVHFYNSTSILQRRVVFRAD+  VK
Sbjct: 129 EQGAIPDDVTIQVLTQCRPELIERTFLACQGAPRAIVHFYNSTSILQRRVVFRADRDAVK 188

Query: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252
            IATDGAR CVEEA KYPGT WR+EYSPESYTGTELEYA +VC+AV EV+QPTP+ P+I 
Sbjct: 189 QIATDGARMCVEEAKKYPGTQWRYEYSPESYTGTELEYAVEVCNAVAEVVQPTPEWPLIV 248

Query: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312
           NLPATVEMATPNVYADSIEWM R+L  R+S+ILSLHPHNDRGTAVAAAELGY AGADRIE
Sbjct: 249 NLPATVEMATPNVYADSIEWMHRHLTPRDSIILSLHPHNDRGTAVAAAELGYAAGADRIE 308

Query: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372
           GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCN+L V ERHPYGGD
Sbjct: 309 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLAVPERHPYGGD 368

Query: 373 LVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVN 432
           LVYTAFSGSHQDAINKGLD MK            +LWQVPYLPIDP+DVGRTYEAVIRVN
Sbjct: 369 LVYTAFSGSHQDAINKGLDAMKFDADAADKDVDDLLWQVPYLPIDPKDVGRTYEAVIRVN 428

Query: 433 SQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPV 492
           SQSGKGGVAYIMKADHGL LPRRLQIEFS+ IQ+I++GEGGE++P EMWD F+EEYL+PV
Sbjct: 429 SQSGKGGVAYIMKADHGLALPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFYEEYLAPV 488

Query: 493 QPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVL 552
            PLERI+Q+V+AAE DGG+ +I A VKI+GEE EI G GNGPLAAF+DA+G VG  V VL
Sbjct: 489 TPLERIRQKVDAAEVDGGTDTITAVVKIDGEEREIVGAGNGPLAAFVDAVGAVGFNVNVL 548

Query: 553 DYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           DYSEH                 + G T WGVGIA SITTASLRAVVSAVNRA
Sbjct: 549 DYSEHAMSAGEEAQAAAYVEAEIDGRTVWGVGIATSITTASLRAVVSAVNRA 600


>tr|A0R5Q2|A0R5Q2_MYCS2 Tax_Id=246196 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium smegmatis]
          Length = 602

 Score =  926 bits (2393), Expect = 0.0
 Identities = 457/592 (77%), Positives = 496/592 (83%)

Query: 13  ADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72
           +DA+ +  +IT P G P PGQP WN QR +SMPV RYR FA EVE I L DRTWPD+VI+
Sbjct: 8   SDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVIE 67

Query: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132
            AP+WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII
Sbjct: 68  TAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 127

Query: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192
            D  IPDDVTIQVLTQ RPELI RTFEAC  A  VIVHFYNSTSILQRRVVFRAD+A +K
Sbjct: 128 EDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRADKAAIK 187

Query: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252
            IATD A   +EEA KYP T+WR+EYSPESYTGTEL YAK+VCDAV E++  TPDNP+I 
Sbjct: 188 KIATDAAELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVIL 247

Query: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312
           NLPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELGY AGADRIE
Sbjct: 248 NLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRIE 307

Query: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372
           GCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYGGD
Sbjct: 308 GCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGD 367

Query: 373 LVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVN 432
           LVYTAFSGSHQDAINKGLDQMK+           ILWQVPYLPIDP+DVGRTYEAVIRVN
Sbjct: 368 LVYTAFSGSHQDAINKGLDQMKVDADAAGADMDDILWQVPYLPIDPKDVGRTYEAVIRVN 427

Query: 433 SQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPV 492
           SQSGKGGVAYIMKADHGL LPRRLQIEFS+ IQ+I++GEGGE++P EMWD F EEYL+P+
Sbjct: 428 SQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAPI 487

Query: 493 QPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVL 552
            PLER++Q+V+AAEEDGG+  I A VK+NGEE EI G GNGPLAAF DALG +G+ V V 
Sbjct: 488 TPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNVR 547

Query: 553 DYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           DYSEH                 + G T WGVGIA SITTASLRAVVSAVNRA
Sbjct: 548 DYSEHAMSAGEEAQAAAYVEAEIDGKTVWGVGIATSITTASLRAVVSAVNRA 599


>tr|Q5Z341|Q5Z341_NOCFA Tax_Id=37329 (leuA)SubName: Full=Putative
           2-isopropylmalate synthase;[Nocardia farcinica]
          Length = 597

 Score =  916 bits (2367), Expect = 0.0
 Identities = 450/594 (75%), Positives = 496/594 (83%), Gaps = 1/594 (0%)

Query: 12  PADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           PADAY S    IT P  P    QP WN Q+ +SMP +RYRPFA+EVEP+ L DRTWPD+V
Sbjct: 3   PADAYVSGSRHITAPSKPAPADQPAWNAQKNSSMPAYRYRPFAEEVEPVTLPDRTWPDKV 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           ID AP WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTD+DFVRE
Sbjct: 63  IDRAPGWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDYDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II D  IPDDVTIQVLTQCRPELIERTFEAC  A+ VIVHFYNSTSILQRRVVFRAD+  
Sbjct: 123 IIEDNAIPDDVTIQVLTQCRPELIERTFEACAGAANVIVHFYNSTSILQRRVVFRADREQ 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           VK IATD A+ C+E   +YP T+WR+EYSPESYTGTELEYA++VCDAV E+I PTP+ P+
Sbjct: 183 VKKIATDAAKLCLEVEKRYPDTNWRYEYSPESYTGTELEYAREVCDAVSEIIAPTPEKPL 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEMATPNVYADSIEWMSRNLA RES++LSLHPHNDRGTAVAAAELGY AGADR
Sbjct: 243 IINLPATVEMATPNVYADSIEWMSRNLARRESIVLSLHPHNDRGTAVAAAELGYQAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTLG+N+FSRG+DPQIDFS+IDEIRRTVEYCN+L VHERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLGMNMFSRGIDPQIDFSDIDEIRRTVEYCNQLPVHERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIR 430
           GDLVYTAFSGSHQDAINKGLD MK            I+W+VPYLPIDP+DVGRTYEAVIR
Sbjct: 363 GDLVYTAFSGSHQDAINKGLDAMKAAADAQNADVSDIVWEVPYLPIDPKDVGRTYEAVIR 422

Query: 431 VNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLS 490
           VNSQSGKGGVAYIMK DHGL LPRRLQIEFS+ +QKI++GEGGE+TP EMWDVF EEYL+
Sbjct: 423 VNSQSGKGGVAYIMKTDHGLVLPRRLQIEFSQVVQKITDGEGGEVTPKEMWDVFHEEYLA 482

Query: 491 PVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVA 550
           P++PLERI+Q+V AAE DGG  SI A VK++G E EI+G GNGPLAAF+DA+  VG  V 
Sbjct: 483 PIRPLERIRQKVTAAETDGGVDSITAVVKVDGVEQEITGQGNGPLAAFVDAIATVGYDVR 542

Query: 551 VLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           VLDYSEH                ++     WGVGIA SITTASLRAVVSAVNRA
Sbjct: 543 VLDYSEHAMSAGDDAQAAAYVECAIGDKVVWGVGIATSITTASLRAVVSAVNRA 596


>tr|C1B9P5|C1B9P5_RHOOB Tax_Id=632772 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus opacus]
          Length = 602

 Score =  915 bits (2364), Expect = 0.0
 Identities = 455/599 (75%), Positives = 499/599 (83%), Gaps = 6/599 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           PADA+ S   +IT P  P    QP WN Q+ +SMP FRYR F++EVEP+ L DRTWPD++
Sbjct: 3   PADAFTSGTRTITPPSKPAPSDQPIWNTQKNSSMPTFRYRSFSEEVEPVSLPDRTWPDKI 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           ID AP WCAVDLRDGNQALIDPMSP  KRRMF+LLVRMGYKEIEVGFPSASQTDFDFVRE
Sbjct: 63  IDRAPQWCAVDLRDGNQALIDPMSPARKRRMFELLVRMGYKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II DG IPDDVTIQVLTQ RPELI+RTFEACE A++VIVHFYNSTS+LQRRVVF+AD+  
Sbjct: 123 IIEDGAIPDDVTIQVLTQSRPELIKRTFEACEGANKVIVHFYNSTSVLQRRVVFKADREV 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K IATD A   +EEA KYP T WR+EYSPESYTGTELEYAK+VCDAV EV+QPTP NP+
Sbjct: 183 IKKIATDAATLALEEAKKYPDTQWRWEYSPESYTGTELEYAKEVCDAVTEVLQPTPQNPV 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELGY AGADR
Sbjct: 243 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTLGLN+F+RGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLGLNMFTRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIR 430
           GDLVYTAFSGSHQDAINKGLD MK            ILW VPYLPIDP+DVGRTYEAVIR
Sbjct: 363 GDLVYTAFSGSHQDAINKGLDAMKFDADSQDADVDDILWAVPYLPIDPKDVGRTYEAVIR 422

Query: 431 VNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLS 490
           VNSQSGKGGVAYIMKADHGL LPRRLQIEFS+A+Q+I++GEGGE++P EMWDVF EEYL+
Sbjct: 423 VNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAVQRITDGEGGEVSPKEMWDVFHEEYLA 482

Query: 491 PVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVA 550
           P+ PLER+KQ+V AAEEDGG+ SI ATVK+NG+E EISG GNGPLAAF+DAL  +   V 
Sbjct: 483 PITPLERMKQKVTAAEEDGGTDSITATVKVNGKEHEISGSGNGPLAAFVDALATIDFDVR 542

Query: 551 VLDYSEHXXXXXXXXXXXXXXXXSV-----HGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           VLDYSEH                +V          WGVGIA SITTASLRAVVSAVNRA
Sbjct: 543 VLDYSEHAMSAGDDAQAAAYVECAVTAPDGRNTVVWGVGIATSITTASLRAVVSAVNRA 601


>tr|B1MFN6|B1MFN6_MYCA9 Tax_Id=561007 SubName: Full=Probable
           2-isopropylmalate synthase (LeuA);[Mycobacterium
           abscessus]
          Length = 607

 Score =  911 bits (2354), Expect = 0.0
 Identities = 451/599 (75%), Positives = 500/599 (83%), Gaps = 7/599 (1%)

Query: 13  ADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVI 71
           +D +   P S+  P GP    QP WN Q+ +SMPV RYR F  EVE I L DRTWPD+VI
Sbjct: 6   SDEFNYTPRSVVTPNGPIPADQPAWNTQKNSSMPVHRYRSFTDEVEKIELPDRTWPDKVI 65

Query: 72  DCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 131
             AP W AVDLRDGNQALIDPMSP  KRRMFDL +RMG+KEIEVGFPSASQTDFDF+RE+
Sbjct: 66  TRAPQWGAVDLRDGNQALIDPMSPARKRRMFDLQIRMGFKEIEVGFPSASQTDFDFIREL 125

Query: 132 ITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATV 191
           IT+  IPDDVTIQVLTQCRPELIERTF ACE AS+VIVHFYNSTSILQRRVVFR D+  +
Sbjct: 126 ITENAIPDDVTIQVLTQCRPELIERTFLACEGASKVIVHFYNSTSILQRRVVFREDKDAI 185

Query: 192 KAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPII 251
           K IATDGA KCVEEA KYP THWRF+YSPESYTGTEL+YA +VC+AVG++++PTPDNPII
Sbjct: 186 KKIATDGAHKCVEEAAKYPDTHWRFQYSPESYTGTELQYALEVCNAVGDIVEPTPDNPII 245

Query: 252 FNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRI 311
           FNLP+TVEM TPNVYADSIEWMSRNLA R+SVILSLHPHNDRGTAVAAAELG+ AGADRI
Sbjct: 246 FNLPSTVEMTTPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGFQAGADRI 305

Query: 312 EGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGG 371
           EGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIR TVEYCN+L+V ERHPYGG
Sbjct: 306 EGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRHTVEYCNQLKVPERHPYGG 365

Query: 372 DLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRV 431
           DLVYTAFSGSHQDAINKGLDQMK            ILWQVPYLPIDP+DVGR YEAVIRV
Sbjct: 366 DLVYTAFSGSHQDAINKGLDQMKRDADEADSDVDDILWQVPYLPIDPKDVGRNYEAVIRV 425

Query: 432 NSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSP 491
           NSQSGKGGVAYIMK+DHGL LPRRLQIEF+++IQ+I++GEGGE+ P E+WDVF EEYL+P
Sbjct: 426 NSQSGKGGVAYIMKSDHGLVLPRRLQIEFAQSIQRITDGEGGEVNPKEIWDVFAEEYLAP 485

Query: 492 VQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAV 551
           + PLERI+Q+V A+EEDGG+ SIAA VKI+G+ETE++G GNGPLAAF+DAL  VG  V V
Sbjct: 486 ITPLERIRQKVTASEEDGGTDSIAAVVKIDGKETEVNGTGNGPLAAFVDALSTVGYTVNV 545

Query: 552 LDYSEHXXXXXXXXXXXXXXXXSV------HGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           LDYSEH                +V         T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 546 LDYSEHALSAGDDAQAAAYVEATVVSPGGGEAQTVWGVGIAPSITTASLRAVVSAVNRA 604


>tr|Q0S8X0|Q0S8X0_RHOSR Tax_Id=101510 (leuA1)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus sp.]
          Length = 602

 Score =  910 bits (2352), Expect = 0.0
 Identities = 452/599 (75%), Positives = 501/599 (83%), Gaps = 6/599 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           PADA+ S   +IT P  P    QP+WN Q+ +SMP FRYR F++EVEP+ L DR+WPD+V
Sbjct: 3   PADAFTSGTRTITPPSKPAPSDQPEWNTQKNSSMPTFRYRSFSEEVEPVSLPDRSWPDKV 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           ID AP WCAVDLRDGNQALIDPMSP  KRRMF+LLVRMGYKEIEVGFPSASQTDFDFVRE
Sbjct: 63  IDRAPQWCAVDLRDGNQALIDPMSPARKRRMFELLVRMGYKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II DG IPDDVTIQVLTQ RPELI+RTFEACE A++VIVHFYNSTSILQRRVVF+A++  
Sbjct: 123 IIEDGAIPDDVTIQVLTQSRPELIKRTFEACEGANKVIVHFYNSTSILQRRVVFKAERDV 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K IATD A   +EEA +YP T WR+EYSPESYTGTELEYAK+VCDAV EV+QPTP+NP+
Sbjct: 183 IKKIATDAATLALEEAKQYPDTQWRWEYSPESYTGTELEYAKEVCDAVTEVLQPTPENPV 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELGY AGADR
Sbjct: 243 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTLGLN+F+RGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLGLNMFTRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIR 430
           GDLVYTAFSGSHQDAINKGLD MK            ILW VPYLPIDP+DVGRTYEAVIR
Sbjct: 363 GDLVYTAFSGSHQDAINKGLDAMKFDADSQDADVDDILWAVPYLPIDPKDVGRTYEAVIR 422

Query: 431 VNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLS 490
           VNSQSGKGGVAYIMKADHGL LPRRLQIEFS+A+Q+I++GEGGE++P EMWDVF EEYL+
Sbjct: 423 VNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAVQRITDGEGGEVSPKEMWDVFHEEYLA 482

Query: 491 PVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVA 550
           P+ PLER+KQ+V A+EEDGG+ SI ATVK++G+E EISG GNGPLAAF+DAL  +   V 
Sbjct: 483 PITPLERMKQKVTASEEDGGTDSITATVKVDGKEHEISGSGNGPLAAFVDALATIDFDVR 542

Query: 551 VLDYSEHXXXXXXXXXXXXXXXXSV-----HGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           VLDYSEH                +V          WGVGIA SITTASLRAVVSAVNRA
Sbjct: 543 VLDYSEHAMSAGDDAQAAAYVECAVTAPDGRNTVVWGVGIATSITTASLRAVVSAVNRA 601


>tr|C0ZN67|C0ZN67_RHOE4 Tax_Id=234621 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus erythropolis]
          Length = 602

 Score =  905 bits (2338), Expect = 0.0
 Identities = 450/599 (75%), Positives = 495/599 (82%), Gaps = 6/599 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           PADA+ +   +IT P  P    QP WN Q+ +SMP FRYRPFA+EVE + L DRTWPD++
Sbjct: 3   PADAFTTGTRTITPPTKPAPSDQPAWNTQKNSSMPTFRYRPFAEEVETVTLPDRTWPDKI 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           ID AP WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE
Sbjct: 63  IDRAPQWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II DG IP DVTIQVLTQ RPELI+RTFEACE A   IVHFYNSTSILQRRVVFRAD+ T
Sbjct: 123 IIEDGAIPSDVTIQVLTQSRPELIKRTFEACEGAENAIVHFYNSTSILQRRVVFRADKDT 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K IATD A   + E+ KYP T+WR+EYSPESYTGTELEYAK+VCDAV E +  TP NP+
Sbjct: 183 IKKIATDAAELVLAESKKYPDTNWRWEYSPESYTGTELEYAKEVCDAVTETLGATPANPV 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELGY AGADR
Sbjct: 243 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTL LN+F+RGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLALNMFTRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIR 430
           GDLVYTAFSGSHQDAINKGLD MK+           ILWQVPYLPIDP+DVGR+YEAVIR
Sbjct: 363 GDLVYTAFSGSHQDAINKGLDAMKVDADNQDSDVDDILWQVPYLPIDPKDVGRSYEAVIR 422

Query: 431 VNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLS 490
           VNSQSGKGGVAYIMKADHGL LPRRLQ+EFS+++QKI++GEGGE++P EMWDVF EEYL+
Sbjct: 423 VNSQSGKGGVAYIMKADHGLVLPRRLQVEFSQSVQKITDGEGGEVSPKEMWDVFHEEYLA 482

Query: 491 PVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVA 550
           PV PLER+KQ+V A+EEDGG+ +I A VK+NG+E EISG GNGPLAAF+DALG +   V 
Sbjct: 483 PVTPLERMKQKVTASEEDGGTDAITAIVKVNGKEQEISGTGNGPLAAFVDALGSINFDVR 542

Query: 551 VLDYSEHXXXXXXXXXXXXXXXXSVHG-----HTAWGVGIAPSITTASLRAVVSAVNRA 604
           VLDYSEH                +V G        WGVGIA SITTASLRAVVSAVNRA
Sbjct: 543 VLDYSEHAMSAGDDAQAAAYVECAVTGPDGQSTVVWGVGIATSITTASLRAVVSAVNRA 601


>tr|C3JNY6|C3JNY6_RHOER Tax_Id=596309 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus erythropolis SK121]
          Length = 602

 Score =  904 bits (2337), Expect = 0.0
 Identities = 449/599 (74%), Positives = 495/599 (82%), Gaps = 6/599 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           PADA+ +   +IT P  P    QP WN Q+ +SMP FRYRPFA+EVE + L DRTWPD++
Sbjct: 3   PADAFTTGTRTITPPTKPAPSDQPAWNTQKNSSMPTFRYRPFAEEVETVTLPDRTWPDKI 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           ID AP WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE
Sbjct: 63  IDRAPQWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II DG IP DVTIQVLTQ RPELI+RTFEACE A   IVHFYNSTSILQRRVVFRAD+ T
Sbjct: 123 IIEDGAIPSDVTIQVLTQSRPELIKRTFEACEGAENAIVHFYNSTSILQRRVVFRADKDT 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K IATD A   + E+ KYP T+WR+EYSPESYTGTELEYAK+VCDAV E +  TP NP+
Sbjct: 183 IKKIATDAAELVLAESKKYPDTNWRWEYSPESYTGTELEYAKEVCDAVTETLGATPANPV 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELGY AGADR
Sbjct: 243 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTL LN+F+RGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLALNMFTRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIR 430
           GDLVYTAFSGSHQDAINKGLD MK+           ILWQVPYLPIDP+DVGR+YEAVIR
Sbjct: 363 GDLVYTAFSGSHQDAINKGLDAMKVDADSQNSDVDDILWQVPYLPIDPKDVGRSYEAVIR 422

Query: 431 VNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLS 490
           VNSQSGKGGVAYIMKADHGL LPRRLQ+EFS+++QKI++GEGGE++P EMWDVF EEYL+
Sbjct: 423 VNSQSGKGGVAYIMKADHGLVLPRRLQVEFSQSVQKITDGEGGEVSPKEMWDVFHEEYLA 482

Query: 491 PVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVA 550
           P+ PLER+KQ+V A+EEDGG+ +I A VK+NG+E EISG GNGPLAAF+DALG +   V 
Sbjct: 483 PITPLERMKQKVTASEEDGGTDAITAIVKVNGKEQEISGTGNGPLAAFVDALGSINFDVR 542

Query: 551 VLDYSEHXXXXXXXXXXXXXXXXSVHG-----HTAWGVGIAPSITTASLRAVVSAVNRA 604
           VLDYSEH                +V G        WGVGIA SITTASLRAVVSAVNRA
Sbjct: 543 VLDYSEHAMSAGDDAQAAAYVECAVTGPEGQSTVVWGVGIATSITTASLRAVVSAVNRA 601


>tr|C2AJL2|C2AJL2_TSUPA Tax_Id=521096 SubName:
           Full=2-isopropylmalate synthase;[Tsukamurella
           paurometabola DSM 20162]
          Length = 622

 Score =  904 bits (2335), Expect = 0.0
 Identities = 450/597 (75%), Positives = 494/597 (82%), Gaps = 5/597 (0%)

Query: 13  ADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVI 71
           AD+Y S  S I+ P GP +PGQP WNPQR+++MP  RYRPFA EVE I L DRTWPD V 
Sbjct: 5   ADSYTSGVSKISTPAGPRNPGQPAWNPQRSSAMPNHRYRPFADEVEQISLPDRTWPDNVA 64

Query: 72  DCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 131
           D APLWCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI
Sbjct: 65  DTAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 124

Query: 132 ITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATV 191
           I DG IPDDVTIQVL QCR ELIERTFEAC+ A  VIVHFYNSTS+LQRRVVFRAD+A +
Sbjct: 125 IEDGAIPDDVTIQVLVQCRDELIERTFEACQGAKNVIVHFYNSTSVLQRRVVFRADKAAI 184

Query: 192 KAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPII 251
           K IATD A K +EE  KYP T WR++YSPESYTGTEL +AK+VCDAV E+I PTP+NP+I
Sbjct: 185 KKIATDAAHKVLEEQKKYPDTAWRYQYSPESYTGTELSFAKEVCDAVTEIIAPTPENPMI 244

Query: 252 FNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRI 311
            NLPATVEMATPNVYADSIEWMSRNL  R+SVILSLHPHNDRG  VAAAELGY AGADRI
Sbjct: 245 LNLPATVEMATPNVYADSIEWMSRNLDRRDSVILSLHPHNDRGEGVAAAELGYLAGADRI 304

Query: 312 EGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGG 371
           EGCLFGNGERTGNVCLVTLGLN+FSRG+DPQI+F++IDEIRRTVEYCN+L V ERHPYGG
Sbjct: 305 EGCLFGNGERTGNVCLVTLGLNMFSRGIDPQINFADIDEIRRTVEYCNQLPVPERHPYGG 364

Query: 372 DLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRV 431
           DLVYTAFSGSHQDAINKGLDQMKI           ILWQVPYLPIDP+DVGR+YEAVIRV
Sbjct: 365 DLVYTAFSGSHQDAINKGLDQMKIDADEADKDVDDILWQVPYLPIDPKDVGRSYEAVIRV 424

Query: 432 NSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSP 491
           NSQSGKGGVAYIMK+DHGL LPRRLQIEFS+++QKI++GEGGE+TP EMWDVF  EY+ P
Sbjct: 425 NSQSGKGGVAYIMKSDHGLALPRRLQIEFSQSVQKITDGEGGEVTPKEMWDVFAGEYIDP 484

Query: 492 VQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAV 551
           + PLER++Q+V A+E DG    I A VK+ G+E EISG GNGPLAAF+DA+G VG  V V
Sbjct: 485 ILPLERMRQKVTASEIDGAVDRIEAVVKVEGKEQEISGEGNGPLAAFVDAIGTVGFDVRV 544

Query: 552 LDYSEHXXXXXXXXXXXXXXXXSV----HGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           LDYSEH                 V       T WGVGIAPSITTASLRAVVSAVNRA
Sbjct: 545 LDYSEHALSAGDDAQAAAYVEAIVRVGDEDRTVWGVGIAPSITTASLRAVVSAVNRA 601


>tr|D0LDG8|D0LDG8_9ACTO Tax_Id=526226 SubName:
           Full=2-isopropylmalate synthase;[Gordonia bronchialis
           DSM 43247]
          Length = 617

 Score =  897 bits (2317), Expect = 0.0
 Identities = 445/593 (75%), Positives = 485/593 (81%), Gaps = 1/593 (0%)

Query: 13  ADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVI 71
           AD + S  S I +P GP   GQP WN QR ++MP+ RYR FA EVE I + DRTWPD+VI
Sbjct: 4   ADTFTSGASRIVEPSGPIPAGQPAWNTQRGSAMPIHRYRQFADEVETISIPDRTWPDKVI 63

Query: 72  DCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 131
             AP+W AVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTD+DFVREI
Sbjct: 64  TKAPMWGAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDYDFVREI 123

Query: 132 ITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATV 191
           I DG IPDDVTIQVLTQCR ELIERTF+AC  A++VIVHFYNSTS+LQRRVVFRAD+  +
Sbjct: 124 IEDGAIPDDVTIQVLTQCRDELIERTFDACRGANKVIVHFYNSTSVLQRRVVFRADKDAI 183

Query: 192 KAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPII 251
             IATD A K + E  KYP T WR+EYSPESYTGTEL YAK VCDAV E+I PTPDNP+I
Sbjct: 184 TKIATDAAHKVLVEQAKYPDTQWRYEYSPESYTGTELSYAKHVCDAVTEIIAPTPDNPMI 243

Query: 252 FNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRI 311
            NLPATVEMATPNVYADSIEWM RNL  R+S+ILSLHPHNDRGTAVAAAELGY AGADRI
Sbjct: 244 INLPATVEMATPNVYADSIEWMHRNLERRDSIILSLHPHNDRGTAVAAAELGYQAGADRI 303

Query: 312 EGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGG 371
           EGCLFGNGERTGNVCLVTLG+NLFSRGVDPQI FS+IDEIRRTVEYCN+L V ERHPYGG
Sbjct: 304 EGCLFGNGERTGNVCLVTLGMNLFSRGVDPQISFSDIDEIRRTVEYCNQLNVPERHPYGG 363

Query: 372 DLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRV 431
           DLVYTAFSGSHQDAINKGLDQMK            ILWQVPYLPIDP+DVGR YEAVIRV
Sbjct: 364 DLVYTAFSGSHQDAINKGLDQMKYDADASDRDVDDILWQVPYLPIDPKDVGRNYEAVIRV 423

Query: 432 NSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSP 491
           NSQSGKGGVAYIMKADHG+ LPRRLQIEFSR IQKI++GEGGE+ P EMWDVF E YL+P
Sbjct: 424 NSQSGKGGVAYIMKADHGMNLPRRLQIEFSREIQKITDGEGGEVNPKEMWDVFAENYLAP 483

Query: 492 VQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAV 551
           + PLER++Q+V+AAE DGG   I A VK+ G E EI+G GNGPLAAF+DAL  VG  V V
Sbjct: 484 IWPLERMRQKVDAAEVDGGEDRITAIVKVEGNEREIAGSGNGPLAAFVDALSTVGYDVRV 543

Query: 552 LDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           LDYSEH                 V+G T WGVG+A SITTASLRAVVSAVNRA
Sbjct: 544 LDYSEHALTSGGDASAAAYVEAEVNGETVWGVGVASSITTASLRAVVSAVNRA 596


>tr|C6WF52|C6WF52_ACTMD Tax_Id=446462 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Actinosynnema mirum]
          Length = 598

 Score =  815 bits (2104), Expect = 0.0
 Identities = 399/592 (67%), Positives = 467/592 (78%), Gaps = 3/592 (0%)

Query: 14  DAYKSAPSITKPMGPPSP-GQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72
           DAY +  S  +P   P+P GQP WNPQR TSMPV RYRPF + VE + L DRTWP + I 
Sbjct: 7   DAYSTGTSRIRPPARPAPEGQPAWNPQRGTSMPVHRYRPFHELVETVDLPDRTWPAKRIT 66

Query: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132
            AP WCAVDLRDGNQALIDPMSP  KR+MFDLLVRMGYKEIEVGFP+ASQTDFDFVREII
Sbjct: 67  QAPQWCAVDLRDGNQALIDPMSPARKRKMFDLLVRMGYKEIEVGFPAASQTDFDFVREII 126

Query: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192
            DG +PDDVTIQVLTQCRPELI RT+E+   A + IVHFYNSTS+LQR+VVFRAD+  +K
Sbjct: 127 EDGAVPDDVTIQVLTQCRPELITRTYESLRGAHKAIVHFYNSTSVLQRKVVFRADRDRIK 186

Query: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252
           AIATD AR  +EEA KYP T +R+EYSPESYTGTEL YA +VCDAV E+I PTP+ P++ 
Sbjct: 187 AIATDAARFALEEAKKYPETEFRYEYSPESYTGTELSYALEVCDAVSEIIAPTPELPMVI 246

Query: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312
           NLPATVEMATPNVYADSIEWMSR+LA R+S++LSLHPHNDRGT VAAAELGY AGADRIE
Sbjct: 247 NLPATVEMATPNVYADSIEWMSRHLARRDSIVLSLHPHNDRGTGVAAAELGYLAGADRIE 306

Query: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372
           GCLFGNGERTGNVCLVTLG+N+FS+GVDPQIDFS+IDE+RRTVEYCN+L VHERHPYGGD
Sbjct: 307 GCLFGNGERTGNVCLVTLGMNMFSQGVDPQIDFSDIDEVRRTVEYCNQLPVHERHPYGGD 366

Query: 373 LVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVN 432
           LV+TAFSGSHQDAI KG + ++              W+VPYLPIDP+DVGR YEAVIRVN
Sbjct: 367 LVFTAFSGSHQDAIKKGFEALEADAKDADKHVDEYPWEVPYLPIDPKDVGRNYEAVIRVN 426

Query: 433 SQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPV 492
           SQSGKGGVAY+MK++H L+LPRRLQ+EFSR IQ++++ +GGE+ P E+WD F +EYL  V
Sbjct: 427 SQSGKGGVAYVMKSEHHLDLPRRLQVEFSRVIQEVTDTQGGEVGPKEIWDAFADEYLQGV 486

Query: 493 QPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVL 552
            PL  +K  +++  +  GS SI   + ++GE  +++G GNGP+AAF+DAL  VG  V VL
Sbjct: 487 APLRLLKHELSS--DGTGSESIKTVLVVDGETQDVTGTGNGPIAAFVDALASVGYDVRVL 544

Query: 553 DYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           DYSEH                SV     WGVG+  S   ASLRA+VSAVNRA
Sbjct: 545 DYSEHALSSGDDARAASYVECSVGDRVLWGVGVDSSTVAASLRALVSAVNRA 596


>tr|A4F6E9|A4F6E9_SACEN Tax_Id=405948 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Saccharopolyspora erythraea]
          Length = 596

 Score =  781 bits (2017), Expect = 0.0
 Identities = 385/583 (66%), Positives = 452/583 (77%), Gaps = 3/583 (0%)

Query: 22  ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVIDCAPLWCAVD 81
           + KP  P    Q  WNPQ  +SMP  RYRPF + VE + L DRTWPD  I  APLWCAVD
Sbjct: 15  VRKPSRPAPADQQPWNPQLGSSMPFHRYRPFHELVEDVSLPDRTWPDNRITRAPLWCAVD 74

Query: 82  LRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIITDGTIPDDV 141
           LRDGNQALIDPMSP  KRRMFDLLVRMG+KEIEVGFP+ASQTDFDFVREII DG +PDDV
Sbjct: 75  LRDGNQALIDPMSPARKRRMFDLLVRMGFKEIEVGFPAASQTDFDFVREIIEDGAVPDDV 134

Query: 142 TIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVKAIATDGARK 201
            IQVLTQCRPELIERTF + E A++ +VH YNSTSILQRRVVFR ++  +K IAT GA  
Sbjct: 135 RIQVLTQCRPELIERTFASLEGAAKAVVHIYNSTSILQRRVVFREEREGIKKIATMGAEM 194

Query: 202 CVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIFNLPATVEMA 261
            +E A KYP T +RF+YSPESYTGTEL YA +VCDAV E+ QPTP+ P+I NLPATVEMA
Sbjct: 195 ALEFAGKYPDTDFRFQYSPESYTGTELSYAAEVCDAVTEIWQPTPERPVILNLPATVEMA 254

Query: 262 TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIEGCLFGNGER 321
           TPNVYADSIEWM RNL+ R+SV+LSLHPHNDRGT +AAAELGY AGADRIEGCLFGNGER
Sbjct: 255 TPNVYADSIEWMHRNLSRRDSVLLSLHPHNDRGTGIAAAELGYQAGADRIEGCLFGNGER 314

Query: 322 TGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGDLVYTAFSGS 381
           TGNV LV LG+NLFS+G+DPQIDFS++D I+RTVE+CN+L VHERHP+GG+LVYTAFSGS
Sbjct: 315 TGNVDLVALGMNLFSQGIDPQIDFSDLDYIKRTVEHCNQLPVHERHPWGGELVYTAFSGS 374

Query: 382 HQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVA 441
           HQDAINKGL+ ++              W+VPYLPIDP+DVGR+YEAVIRVNSQSGKGGVA
Sbjct: 375 HQDAINKGLNALREEAAKAGAEVDAHPWEVPYLPIDPKDVGRSYEAVIRVNSQSGKGGVA 434

Query: 442 YIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPVQPLERIKQR 501
           YIMK +H L+LPR++QIEFS+ +Q  ++ EGGE+TP +MW VF +EYL    PLE ++QR
Sbjct: 435 YIMKTEHQLDLPRKMQIEFSKLVQARTDSEGGEVTPDQMWAVFSDEYLGARTPLELVRQR 494

Query: 502 VNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVLDYSEHXXXX 561
           ++    + G  +I ATV ++G+E EI+G GNGP+AAF+DAL  VG  V V+DYSEH    
Sbjct: 495 LDG---EAGDETITATVVVDGDEREITGSGNGPIAAFVDALSTVGFDVRVMDYSEHALTA 551

Query: 562 XXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
                       +V     WGV I  S   ASL A+VSAVNRA
Sbjct: 552 GDDALAAAYLECAVGDDVLWGVAIDSSTVKASLHAIVSAVNRA 594


>tr|C5VA14|C5VA14_9CORY Tax_Id=553207 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium matruchotii ATCC 14266]
          Length = 608

 Score =  778 bits (2009), Expect = 0.0
 Identities = 388/600 (64%), Positives = 450/600 (75%), Gaps = 9/600 (1%)

Query: 14  DAYKSAPS--ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVI 71
           D + SAP+  ITKP G P   QP+WN QR ++MP  RY+PFA+EVE + L DRTWPD  I
Sbjct: 5   DTFISAPTSDITKPAGEPPADQPKWNKQRGSAMPAHRYQPFAQEVEDVTLPDRTWPDNKI 64

Query: 72  DCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 131
             AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV+MGYKEIEVGFPSASQTDFDFVREI
Sbjct: 65  THAPAWCAVDLRDGNQALIDPMSPERKRRMFNLLVQMGYKEIEVGFPSASQTDFDFVREI 124

Query: 132 ITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATV 191
           I    IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTSILQR VVFR D+A +
Sbjct: 125 IEQDMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRNVVFRKDKAAI 184

Query: 192 KAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPII 251
           K +ATD        A +YP T+WR+EYSPES+TGTEL YAK+V DAV EV+ PTP+NPII
Sbjct: 185 KKLATDAGELIKTIAKEYPDTNWRWEYSPESFTGTELAYAKEVVDAVVEVMDPTPENPII 244

Query: 252 FNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRI 311
            NLP+TVEM TPNVYAD+IEWM RNL  R+S+ILSLHPHNDRGT VA+AEL + AGADRI
Sbjct: 245 INLPSTVEMITPNVYADAIEWMHRNLNRRDSIILSLHPHNDRGTGVASAELAFMAGADRI 304

Query: 312 EGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGG 371
           EGCLFGNGERTGNVCLVTLGLNL ++GVDPQIDF+NI++IR TVEYCN+LRV ERHPYGG
Sbjct: 305 EGCLFGNGERTGNVCLVTLGLNLLTQGVDPQIDFTNINQIRSTVEYCNQLRVPERHPYGG 364

Query: 372 DLVYTAFSGSHQDAINKGLDQMKI-------XXXXXXXXXXXILWQVPYLPIDPRDVGRT 424
           DLV+TAFSGSHQDA+NKGLD M                     LW+VPYLPIDP+DVGR 
Sbjct: 365 DLVFTAFSGSHQDAVNKGLDAMAARVHPGANHSDVKWEQLRDELWEVPYLPIDPKDVGRN 424

Query: 425 YEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVF 484
           YEAVIRVNSQSGKGGVAYIMK DHG+ LPR +Q+EFS  +Q +++ +GGEI    MWD+F
Sbjct: 425 YEAVIRVNSQSGKGGVAYIMKTDHGMVLPRPMQVEFSSVVQDVTDAQGGEIESKAMWDIF 484

Query: 485 FEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGH 544
            E YL    PLE++  RV+AA  +     I A ++  GE   +SG GNGP+AA+ +AL  
Sbjct: 485 AETYLDATTPLEQVAMRVDAAVTERDQAKITAELRFQGESVTVSGTGNGPIAAYANALEQ 544

Query: 545 VGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           +G+ V V +Y++H                 V+G   WGVGIA SIT ASL+AV SAVNRA
Sbjct: 545 LGIDVEVQEYTQHARTAGDDAEAAAYIFADVNGQKVWGVGIAGSITYASLKAVTSAVNRA 604


>tr|Q6NJX5|Q6NJX5_CORDI Tax_Id=1717 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium diphtheriae]
          Length = 605

 Score =  776 bits (2005), Expect = 0.0
 Identities = 392/600 (65%), Positives = 448/600 (74%), Gaps = 8/600 (1%)

Query: 14  DAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72
           D + SAP+ I  P G  +PGQ  WN QR +SM V RY+PF  EVE I L DRTWP + I 
Sbjct: 5   DTFISAPAAIVTPRGDKAPGQAPWNTQRNSSMAVNRYQPFHVEVENIDLPDRTWPQKRIT 64

Query: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132
            AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV MGYKEIEVGFPSASQTDFDFVREII
Sbjct: 65  KAPQWCAVDLRDGNQALIDPMSPERKRRMFNLLVNMGYKEIEVGFPSASQTDFDFVREII 124

Query: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192
            +  IP+DVTIQVL Q R  LI RTFEACE A  VIVHFYNSTSILQR VVFR D+A +K
Sbjct: 125 ENNMIPNDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRDVVFRKDKAAIK 184

Query: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252
            +ATD A      A  YP T+WR+EYSPESYTGTEL YAK+V DAV  V+ PTP+NPII 
Sbjct: 185 KLATDAAELIKSIAVDYPDTNWRWEYSPESYTGTELTYAKEVVDAVVAVMDPTPENPIII 244

Query: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312
           NLP+TVEM TPNVYAD IEWM RNL  R+S+ILSLHPHNDRGT VAAAELGY AGADRIE
Sbjct: 245 NLPSTVEMITPNVYADGIEWMHRNLNRRDSIILSLHPHNDRGTGVAAAELGYLAGADRIE 304

Query: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372
           GCLFGNGERTGNVCLVTLGLN+F++GVDPQIDFS+ID+IRRTVEYCN+LRV ERHPYGGD
Sbjct: 305 GCLFGNGERTGNVCLVTLGLNMFTQGVDPQIDFSDIDQIRRTVEYCNQLRVPERHPYGGD 364

Query: 373 LVYTAFSGSHQDAINKGLDQM-------KIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           LV+TAFSGSHQDA+NKGLD M                      W+VPYLPIDP+DVGR Y
Sbjct: 365 LVFTAFSGSHQDAVNKGLDAMASRVHPGATHTEVSWDELRGETWEVPYLPIDPKDVGRNY 424

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFF 485
           EAVIRVNSQSGKGGVAYIMK DHGL LPR +Q+EFS  +Q++++ EGGE+    MWD+F 
Sbjct: 425 EAVIRVNSQSGKGGVAYIMKTDHGLALPRPMQVEFSSIVQEVTDAEGGEVNSKNMWDIFA 484

Query: 486 EEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHV 545
            EYL    P+E++   VNAAE +     I A + +NG ET I G GNGP+AA+ +AL  +
Sbjct: 485 REYLDSTSPVEQVSMSVNAAETENDEARIHARLIVNGSETTIEGHGNGPIAAYANALESL 544

Query: 546 GLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRAM 605
           G+ V V +Y +H                 V+G   WGVGIA SIT ASL+A+ SAVNRA+
Sbjct: 545 GIDVEVQEYEQHARTAGDDAEAAAYILAEVNGKKFWGVGIAGSITYASLKAITSAVNRAL 604


>tr|C0DZP7|C0DZP7_9CORY Tax_Id=566549 SubName: Full=Putative
           uncharacterized protein;[Corynebacterium matruchotii
           ATCC 33806]
          Length = 608

 Score =  775 bits (2002), Expect = 0.0
 Identities = 386/600 (64%), Positives = 450/600 (75%), Gaps = 9/600 (1%)

Query: 14  DAYKSAPS--ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVI 71
           D + SAP+  ITKP G P   QP+WN QR ++MP  RY+PF++EVE + L DRTWP+  I
Sbjct: 5   DTFISAPTSDITKPAGEPPADQPKWNKQRGSAMPAHRYQPFSQEVEDVTLPDRTWPNNKI 64

Query: 72  DCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 131
             AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV+MGYKEIEVGFPSASQTDFDFVREI
Sbjct: 65  THAPAWCAVDLRDGNQALIDPMSPERKRRMFNLLVQMGYKEIEVGFPSASQTDFDFVREI 124

Query: 132 ITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATV 191
           I    IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTSILQR VVFR D+A +
Sbjct: 125 IEQDMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRNVVFRKDKAAI 184

Query: 192 KAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPII 251
           K +ATD        A +YP T+WR+EYSPES+TGTEL YAK+V DAV EV+ PTP+NPII
Sbjct: 185 KKLATDAGELIKTIAKEYPNTNWRWEYSPESFTGTELAYAKEVVDAVVEVMDPTPENPII 244

Query: 252 FNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRI 311
            NLP+TVEM TPNVYAD+IEWM RNL  R+S+ILSLHPHNDRGT VA+AEL + AGADRI
Sbjct: 245 INLPSTVEMITPNVYADAIEWMHRNLNRRDSIILSLHPHNDRGTGVASAELAFMAGADRI 304

Query: 312 EGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGG 371
           EGCLFGNGERTGNVCLVTLGLNL ++GVDPQIDF+NI++IR TVEYCN+LRV ERHPYGG
Sbjct: 305 EGCLFGNGERTGNVCLVTLGLNLLTQGVDPQIDFTNINQIRSTVEYCNQLRVPERHPYGG 364

Query: 372 DLVYTAFSGSHQDAINKGLDQMKI-------XXXXXXXXXXXILWQVPYLPIDPRDVGRT 424
           DLV+TAFSGSHQDA+NKGLD M                     LW+VPYLPIDP+DVGR 
Sbjct: 365 DLVFTAFSGSHQDAVNKGLDAMAARVHPGANHSDVKWEELRDELWEVPYLPIDPKDVGRN 424

Query: 425 YEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVF 484
           YEAVIRVNSQSGKGGVAYIMK DHG+ LPR +Q+EFS  +Q +++ +GGEI    MWD+F
Sbjct: 425 YEAVIRVNSQSGKGGVAYIMKTDHGMVLPRPMQVEFSSVVQDVTDAQGGEIESKAMWDIF 484

Query: 485 FEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGH 544
            E YL    PLE++  RV+AA  +     I A ++  GE   +SG GNGP+AA+ +AL  
Sbjct: 485 AETYLDATTPLEQVAMRVDAAVTEQDQAKITAELRFQGESVTVSGTGNGPIAAYANALEQ 544

Query: 545 VGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           +G+ V V +Y++H                 V+G   WGVGIA SIT ASL+AV SAVNRA
Sbjct: 545 LGIDVEVQEYTQHARTAGDDAEAAAYIFADVNGQKVWGVGIAGSITYASLKAVTSAVNRA 604


>tr|C7MQR7|C7MQR7_SACVD Tax_Id=471857 SubName:
           Full=2-isopropylmalate synthase;[Saccharomonospora
           viridis]
          Length = 594

 Score =  774 bits (1999), Expect = 0.0
 Identities = 384/583 (65%), Positives = 446/583 (76%), Gaps = 4/583 (0%)

Query: 22  ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVIDCAPLWCAVD 81
           I  P  P    QP WN QR +SMP  RYRP+ + VE I L DRTWPD+ I+ APLWCAVD
Sbjct: 14  IRTPSRPAPADQPSWNLQRGSSMPFHRYRPWYRLVEDISLPDRTWPDKRIERAPLWCAVD 73

Query: 82  LRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIITDGTIPDDV 141
           LRDGNQALIDPMSP  KR+ FDLLVRMG+KEIEVGFP+ASQ DFDFVREII D  IPDDV
Sbjct: 74  LRDGNQALIDPMSPARKRKFFDLLVRMGFKEIEVGFPAASQADFDFVREIIEDNAIPDDV 133

Query: 142 TIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVKAIATDGARK 201
            IQVL QCRPELIERTFEA E A R IVH YNSTSILQRRVVFR ++  +K IAT GA  
Sbjct: 134 RIQVLVQCRPELIERTFEALEGAPRAIVHIYNSTSILQRRVVFREEREGIKKIATQGAEL 193

Query: 202 CVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIFNLPATVEMA 261
             E A KYP T +RF+YSPES+TGTEL YA +VC+AV E+ QPTP+NP+I NLPATVEMA
Sbjct: 194 VQEYAAKYPETDFRFQYSPESFTGTELSYAAEVCNAVTEIWQPTPENPVIVNLPATVEMA 253

Query: 262 TPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIEGCLFGNGER 321
           TPNVYAD++EWM+RNL  R+S+ILSLHPHNDRGT +AAAELGY AGADRIEGCLFGNGER
Sbjct: 254 TPNVYADAVEWMNRNLERRDSLILSLHPHNDRGTGIAAAELGYQAGADRIEGCLFGNGER 313

Query: 322 TGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGDLVYTAFSGS 381
           TGNV LV LGLNLFS+G+DPQ+DFS++DEI+RTVEYCN+L+VHER P+ GDLV+TAFSGS
Sbjct: 314 TGNVDLVALGLNLFSQGIDPQLDFSDLDEIKRTVEYCNQLKVHERSPWAGDLVFTAFSGS 373

Query: 382 HQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVA 441
           HQDAINKG D ++              W+VPYLPIDP+DVGRTYEAVIRVNSQSGKGG+A
Sbjct: 374 HQDAINKGFDALRDAADKAGVPVDEYPWEVPYLPIDPKDVGRTYEAVIRVNSQSGKGGIA 433

Query: 442 YIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPVQPLERIKQR 501
           YIMK +H L+LPRRLQIEFS+ IQ+ ++ +GGE+ P  MW  F  EYL P  PLE +++ 
Sbjct: 434 YIMKTEHQLDLPRRLQIEFSKIIQRHTDTKGGEVDPQTMWQAFAAEYLEPKTPLELVRKH 493

Query: 502 VNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVLDYSEHXXXX 561
           V A     G   + AT++++GE  EI+G GNGP+AAF DAL  VG  V +LDYSEH    
Sbjct: 494 VRA----NGDYELTATIRLDGEGQEITGRGNGPIAAFFDALATVGFDVRLLDYSEHTLRP 549

Query: 562 XXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
                       ++     WGVGI  SI TASL AVVSA+NRA
Sbjct: 550 GDDSKAASYIECAIDDKVYWGVGIDSSIITASLLAVVSAINRA 592


>tr|C8NR86|C8NR86_COREF Tax_Id=196164 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium efficiens YS-314]
          Length = 616

 Score =  774 bits (1999), Expect = 0.0
 Identities = 393/602 (65%), Positives = 449/602 (74%), Gaps = 8/602 (1%)

Query: 12  PADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P DA+ SAPS I  P G   P QP WN QR +SMPV RY PF  EVE I L DRTWPD+ 
Sbjct: 3   PNDAFISAPSEIHTPDGDRQPNQPAWNKQRNSSMPVKRYLPFEVEVEDITLPDRTWPDKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV+MG+KEIEVGFPSASQTDFDFVRE
Sbjct: 63  ITQAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVKMGFKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II    IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTSILQR VVFR ++  
Sbjct: 123 IIEKNMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRDVVFRMNKDQ 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           VK +ATD A      A  YP T+WR+EYSPESYTGTE+EYAK+V DAV EV+ PTP+NPI
Sbjct: 183 VKTLATDAAELIKTIAQDYPDTNWRWEYSPESYTGTEVEYAKEVVDAVVEVMDPTPENPI 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEM TPNVYADSIEWM RNL  R+S+ILSLHPHNDRGT VAAAELGY AGADR
Sbjct: 243 IINLPATVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGTGVAAAELGYMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTL LN+ ++GVDPQ+DFS+I  IRRTVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLALNMLTQGVDPQLDFSDIKHIRRTVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXXXXXIL-------WQVPYLPIDPRDVGR 423
           GDLV+TAFSGSHQDAINKGLD +                      W+VPYLPIDP+DVGR
Sbjct: 363 GDLVFTAFSGSHQDAINKGLDALAAKVKPGASSTEVAWEELRSTEWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            YEAVIRVNSQSGKGGVAYIMK DHGL++PR +Q+EFS  +Q +++ EGGE+   EMWD+
Sbjct: 423 DYEAVIRVNSQSGKGGVAYIMKTDHGLKMPRSMQVEFSAVVQNVTDAEGGEVNSKEMWDI 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F  EYL    P+E+I  RV  A+ +    +I A + ++GE   +SG GNGPLAA+ +AL 
Sbjct: 483 FATEYLDRSAPVEQIALRVENAQTENDDATITAELVVDGENQTVSGRGNGPLAAYANALE 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
            + + V + +YS+H                 V+G   WGVGIA SIT ASL+AV SAVNR
Sbjct: 543 SLNIDVEIQEYSQHARTSGDDAEAAAYVLAEVNGRMVWGVGIAGSITYASLKAVTSAVNR 602

Query: 604 AM 605
           A+
Sbjct: 603 AL 604


>sp|P42455|LEU1_CORGL Tax_Id=1718 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthetase;[Corynebacterium glutamicum]
          Length = 616

 Score =  773 bits (1997), Expect = 0.0
 Identities = 387/602 (64%), Positives = 451/602 (74%), Gaps = 8/602 (1%)

Query: 12  PADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P DA+ SAP+ I  P+GP + GQP WN QR +SMPV RY PF  EVE I L DRTWPD+ 
Sbjct: 3   PNDAFISAPAKIETPVGPRNEGQPAWNKQRGSSMPVNRYMPFEVEVEDISLPDRTWPDKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV+MG+KEIEVGFPSASQTDFDFVRE
Sbjct: 63  ITVAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVQMGFKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II  G IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTSILQR VVFR D+  
Sbjct: 123 IIEKGMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRNVVFRMDKVQ 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           VK +ATD A      A  YP T+WR++YSPES+TGTE+EYAK+V DAV EV+ PTP+NP+
Sbjct: 183 VKKLATDAAELIKTIAQDYPDTNWRWQYSPESFTGTEVEYAKEVVDAVVEVMDPTPENPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM TPNVYADSIEWM RNL  R+S+ILSLHPHNDRGT V AAELGY AGADR
Sbjct: 243 IINLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGTGVGAAELGYMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTL LN+ ++GVDPQ+DF++I +IR TVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLALNMLTQGVDPQLDFTDIRQIRSTVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKI-------XXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           GDLV+TAFSGSHQDA+NKGLD M                      W+VPYLPIDP+DVGR
Sbjct: 363 GDLVFTAFSGSHQDAVNKGLDAMAAKVQPGASSTEVSWEQLRDTEWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            YEAVIRVNSQSGKGGVAYIMK DHGL++PR +Q+EFS  +Q +++ EGGE+    MWD+
Sbjct: 423 DYEAVIRVNSQSGKGGVAYIMKTDHGLQIPRSMQVEFSTVVQNVTDAEGGEVNSKAMWDI 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F  EYL    P+E+I  RV  A+ +    SI A +  NG++  + G GNGPLAA+ +AL 
Sbjct: 483 FATEYLERTAPVEQIALRVENAQTENEDASITAELIHNGKDVTVDGRGNGPLAAYANALE 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
            +G+ V + +Y++H                 V+G   WGVGIA SIT ASL+AV SAVNR
Sbjct: 543 KLGIDVEIQEYNQHARTSGDDAEAAAYVLAEVNGRKVWGVGIAGSITYASLKAVTSAVNR 602

Query: 604 AM 605
           A+
Sbjct: 603 AL 604


>tr|Q4JSM3|Q4JSM3_CORJK Tax_Id=306537 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium jeikeium]
          Length = 613

 Score =  773 bits (1996), Expect = 0.0
 Identities = 386/599 (64%), Positives = 447/599 (74%), Gaps = 8/599 (1%)

Query: 14  DAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72
           D + SAP+ I  P G    GQP WN QR +SMP  RY+PF +EVE I L DRTWPD+VID
Sbjct: 4   DTFISAPARINTPNGEIPEGQPAWNKQRNSSMPHVRYQPFFEEVEEITLPDRTWPDKVID 63

Query: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132
            AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV MGYKEIEVGFPSASQTDF+FVREII
Sbjct: 64  RAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVDMGYKEIEVGFPSASQTDFNFVREII 123

Query: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192
               IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTS LQR+VVFR D+  +K
Sbjct: 124 EKNMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSKLQRKVVFRKDKEAIK 183

Query: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252
            +ATD A      A  YP T+WR+EYSPESYTGTE+ YAK+VCDAV EV+ PTP+NPII 
Sbjct: 184 KLATDAAELIKTIAKDYPDTNWRWEYSPESYTGTEVAYAKEVCDAVVEVMDPTPENPIIL 243

Query: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312
           NLP+TVEM TPNVYADSIEWM RNL  R+S+ILSLHPHNDRGT VAAAELGY AGADRIE
Sbjct: 244 NLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGTGVAAAELGYMAGADRIE 303

Query: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372
           GCLFGNGERTGNVCLVTLGLN+ ++GVDPQIDFS+ID++RRTVEYCN+LRV ERHPYGGD
Sbjct: 304 GCLFGNGERTGNVCLVTLGLNMLTQGVDPQIDFSDIDQVRRTVEYCNQLRVPERHPYGGD 363

Query: 373 LVYTAFSGSHQDAINKGLDQM-------KIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           LV+TAFSGSHQDAINKGLD +                      W+VPYLPIDP+DVGR+Y
Sbjct: 364 LVFTAFSGSHQDAINKGLDAIAEKIDPDATAEEVTQEAMVEKTWEVPYLPIDPKDVGRSY 423

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFF 485
           EAVIRVNSQSGKGGVAYIMK DH L+LPR +Q+EFS  +Q +++ EGGE+ P  MWD+F 
Sbjct: 424 EAVIRVNSQSGKGGVAYIMKTDHNLQLPRPMQVEFSSVVQAVTDAEGGEVNPKAMWDIFS 483

Query: 486 EEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHV 545
            EYL  V P+E I   V+  + +G    +   ++ NGE   + G GNGP+ A+ +AL  +
Sbjct: 484 GEYLDRVAPIETISLTVDGGQNEGEEAKVTGQIEFNGEGKTVQGRGNGPINAYCNALEEL 543

Query: 546 GLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           G  V V +YS+H                 ++G   WGVGIA SIT ASL+A+ SAVNR+
Sbjct: 544 GYDVEVQEYSQHARTSGDDAEAAAYVLAEINGAKYWGVGIASSITYASLKAITSAVNRS 602


>tr|C8RV49|C8RV49_CORJE Tax_Id=525262 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium jeikeium ATCC 43734]
          Length = 613

 Score =  773 bits (1996), Expect = 0.0
 Identities = 386/599 (64%), Positives = 447/599 (74%), Gaps = 8/599 (1%)

Query: 14  DAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72
           D + SAP+ I  P G    GQP WN QR +SMP  RY+PF +EVE I L DRTWPD+VID
Sbjct: 4   DTFISAPARINTPNGEIPEGQPAWNKQRNSSMPHVRYQPFFEEVEEITLPDRTWPDKVID 63

Query: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132
            AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV MGYKEIEVGFPSASQTDF+FVREII
Sbjct: 64  RAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVDMGYKEIEVGFPSASQTDFNFVREII 123

Query: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192
               IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTS LQR+VVFR D+  +K
Sbjct: 124 EKNMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSKLQRKVVFRKDKEAIK 183

Query: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252
            +ATD A      A  YP T+WR+EYSPESYTGTE+ YAK+VCDAV EV+ PTP+NPII 
Sbjct: 184 KLATDAAELIKTIAKDYPDTNWRWEYSPESYTGTEVAYAKEVCDAVVEVMDPTPENPIIL 243

Query: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312
           NLP+TVEM TPNVYADSIEWM RNL  R+S+ILSLHPHNDRGT VAAAELGY AGADRIE
Sbjct: 244 NLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGTGVAAAELGYMAGADRIE 303

Query: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372
           GCLFGNGERTGNVCLVTLGLN+ ++GVDPQIDFS+ID++RRTVEYCN+LRV ERHPYGGD
Sbjct: 304 GCLFGNGERTGNVCLVTLGLNMLTQGVDPQIDFSDIDQVRRTVEYCNQLRVPERHPYGGD 363

Query: 373 LVYTAFSGSHQDAINKGLDQM-------KIXXXXXXXXXXXILWQVPYLPIDPRDVGRTY 425
           LV+TAFSGSHQDAINKGLD +                      W+VPYLPIDP+DVGR+Y
Sbjct: 364 LVFTAFSGSHQDAINKGLDAIAEKIDPDATAEEVTQEAMVEKTWEVPYLPIDPKDVGRSY 423

Query: 426 EAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFF 485
           EAVIRVNSQSGKGGVAYIMK DH L+LPR +Q+EFS  +Q +++ EGGE+ P  MWD+F 
Sbjct: 424 EAVIRVNSQSGKGGVAYIMKTDHNLQLPRPMQVEFSSVVQAVTDAEGGEVNPKAMWDIFS 483

Query: 486 EEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHV 545
            EYL  V P+E I   V+  + +G    +   ++ NGE   + G GNGP+ A+ +AL  +
Sbjct: 484 GEYLDRVAPIETISLTVDGGQNEGEEAKVTGQIEFNGEGKTVQGRGNGPINAYCNALEEL 543

Query: 546 GLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           G  V V +YS+H                 ++G   WGVGIA SIT ASL+A+ SAVNR+
Sbjct: 544 GYDVEVQEYSQHARTSGDDAEAAAYVLAEINGAKYWGVGIASSITYASLKAITSAVNRS 602


>tr|B1VIR4|B1VIR4_CORU7 Tax_Id=504474 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium urealyticum]
          Length = 613

 Score =  771 bits (1992), Expect = 0.0
 Identities = 385/607 (63%), Positives = 451/607 (74%), Gaps = 15/607 (2%)

Query: 14  DAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72
           D++ SAP+ I  P G     QP WN QR + MP  RY PF +EV+ I L DRTWPD+VID
Sbjct: 5   DSFISAPAQIQTPNGEIPADQPAWNKQRNSQMPNRRYLPFFEEVDHITLPDRTWPDKVID 64

Query: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132
            AP WCAVDLRDGNQALIDPMSP  KRRMFD+LV MGYKEIEVGFPSASQTD+DFVREII
Sbjct: 65  RAPQWCAVDLRDGNQALIDPMSPERKRRMFDMLVEMGYKEIEVGFPSASQTDYDFVREII 124

Query: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192
            +  IPDDVTIQVL Q R  LI RTFEAC  A  VIVHFYNSTS LQRRVVFR D+  +K
Sbjct: 125 EENKIPDDVTIQVLVQAREHLIRRTFEACAGAKNVIVHFYNSTSELQRRVVFRKDKEGIK 184

Query: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252
            +ATD A    E A  YP T+WR+EYSPES+TGTE+EYAK+VCDAV EVI PTP+NPII 
Sbjct: 185 KLATDAAHLIKEIAQDYPDTNWRWEYSPESFTGTEIEYAKEVCDAVVEVIDPTPENPIII 244

Query: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312
           NLP+TVEM TPNVYADSIEWM RNL  R+S+ILSLHPHNDRG  VAAAELGY AGADRIE
Sbjct: 245 NLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGEGVAAAELGYMAGADRIE 304

Query: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372
           GCLFGNGERTGNVCLVTLGLN+ ++GVDPQIDFS+ID+IRRTVEYCN+LRV ERHPYGG+
Sbjct: 305 GCLFGNGERTGNVCLVTLGLNMLTQGVDPQIDFSDIDQIRRTVEYCNQLRVPERHPYGGE 364

Query: 373 LVYTAFSGSHQDAINKGL--------------DQMKIXXXXXXXXXXXILWQVPYLPIDP 418
           LV+TAFSGSHQDAINKGL              D               + W+VPYLPIDP
Sbjct: 365 LVFTAFSGSHQDAINKGLAAMAERDAAEDTPEDPASADSETLTEAVRNVTWEVPYLPIDP 424

Query: 419 RDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPT 478
           +D+GR+YEAVIRVNSQSGKGGVAYIMK DH L+LPR +Q+EFS  +Q +++ EGGE+ P 
Sbjct: 425 KDIGRSYEAVIRVNSQSGKGGVAYIMKTDHNLDLPRPMQVEFSGIVQAVTDAEGGEVNPK 484

Query: 479 EMWDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAF 538
            MWD+F  EYL    P++ I   V+  + +G  +++ + ++ NGE   + G GNGP+AA+
Sbjct: 485 AMWDIFATEYLDRTAPVDVISTTVDGGQNEGEESAVTSQIEFNGEAKTLKGRGNGPIAAY 544

Query: 539 IDALGHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVV 598
            DAL  +G+ V V +Y++H                 V+G   WGVGIA SIT ASL+AV 
Sbjct: 545 CDALESLGVDVEVQEYNQHARTSGDDAEAAAYVLAEVNGQRVWGVGIAGSITYASLKAVT 604

Query: 599 SAVNRAM 605
           SAVNRA+
Sbjct: 605 SAVNRAL 611


>tr|C4LGL7|C4LGL7_CORK4 Tax_Id=645127 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium kroppenstedtii]
          Length = 613

 Score =  769 bits (1986), Expect = 0.0
 Identities = 385/607 (63%), Positives = 447/607 (73%), Gaps = 14/607 (2%)

Query: 12  PADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P D + SAP+ I+ P G     QP WN QR + MP  RY+P+  EVE I L DRTWPD+ 
Sbjct: 3   PVDEFISAPAHISTPDGDIPADQPSWNKQRPSQMPAGRYQPYFTEVEHITLPDRTWPDKT 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           ID AP+WCAVDLRDGNQALIDPMSP  KRRMF+LLV MGYKEIEVGFPSASQTDF+FVRE
Sbjct: 63  IDHAPVWCAVDLRDGNQALIDPMSPERKRRMFELLVTMGYKEIEVGFPSASQTDFNFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II    IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTSILQR VVFR D+  
Sbjct: 123 IIEQDMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRDVVFRKDKEG 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K +ATD A      A  YPGT+WR+EYSPESYTGTE+ YAK+VCDAV E++ PTP+NPI
Sbjct: 183 IKKLATDAAELIKSIATDYPGTNWRWEYSPESYTGTEVAYAKEVCDAVVEIMDPTPENPI 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM TPNVYADSIEWM RNL  R+S+I+SLHPHNDRGT VA AELG+ AGADR
Sbjct: 243 IINLPSTVEMTTPNVYADSIEWMDRNLNRRDSIIISLHPHNDRGTGVATAELGFMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTLGLN+ ++GVDPQIDFS+ID+IR TVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLGLNMLTQGVDPQIDFSDIDKIRHTVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQM-------------KIXXXXXXXXXXXILWQVPYLPID 417
           GDLV+TAFSGSHQDAINKGLD M                          + W+VPYLPID
Sbjct: 363 GDLVFTAFSGSHQDAINKGLDAMVDKAEKSNATDDTTDTERDRQRIVHRVPWEVPYLPID 422

Query: 418 PRDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITP 477
           P+DVGRTYEAVIRVNSQSGKGGV+YIMK DHG+ +PR +Q+EFS  +Q +++ EGGE+  
Sbjct: 423 PKDVGRTYEAVIRVNSQSGKGGVSYIMKTDHGINMPRAVQVEFSGVVQAVTDAEGGEVNS 482

Query: 478 TEMWDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAA 537
             MWD+F  EYL    P++ I   V+  + +     ++A + INGEE  I+G GNGP+AA
Sbjct: 483 KNMWDIFAGEYLDRDDPIDAISITVDGGQNENEGAEVSAHLIINGEEQTITGHGNGPVAA 542

Query: 538 FIDALGHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAV 597
           + +AL  +G+ V V DYS+H                 V G   WGVGIA SIT ASL+AV
Sbjct: 543 YTNALESIGINVEVQDYSQHSRTSGDDAEAAAYILADVDGTKVWGVGIASSITYASLKAV 602

Query: 598 VSAVNRA 604
            SA NRA
Sbjct: 603 TSAANRA 609


>sp|A4QAP0|LEU1_CORGB Tax_Id=340322 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthetase;[Corynebacterium glutamicum]
          Length = 616

 Score =  766 bits (1979), Expect = 0.0
 Identities = 384/602 (63%), Positives = 449/602 (74%), Gaps = 8/602 (1%)

Query: 12  PADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P DA+ SAP+ I  P+GP + GQP WN QR +SMPV RY PF  EVE I L DRTWPD+ 
Sbjct: 3   PNDAFISAPAKIETPVGPRNEGQPAWNKQRGSSMPVNRYMPFEVEVEDISLPDRTWPDKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV+MG+KEIEVGFPSASQTDFDFVRE
Sbjct: 63  ITVAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVQMGFKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II    IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTSILQR VVFR D+  
Sbjct: 123 IIEKDMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRNVVFRMDKDQ 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           VK +ATD A      A  YP T+WR++YSPES+TGTE+EYAK+V DAV EV+ PTP+NP+
Sbjct: 183 VKKLATDAAELIKTIAQDYPDTNWRWQYSPESFTGTEVEYAKEVVDAVVEVMDPTPENPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM TPNVYADSIEWM RN+  R+S+ILSLHPHNDRGT V AAELGY AGADR
Sbjct: 243 IINLPSTVEMITPNVYADSIEWMHRNVNRRDSIILSLHPHNDRGTGVGAAELGYMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNVCLVTL LN+ ++GVDPQ+DF++I +IR TVEYCN+LRV ERHPY 
Sbjct: 303 IEGCLFGNGERTGNVCLVTLALNMLTQGVDPQLDFTDIRQIRSTVEYCNQLRVPERHPYA 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKI-------XXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           GDLV+TAFSGSHQDA+NKGLD M                      W+VPYLPIDP+DVGR
Sbjct: 363 GDLVFTAFSGSHQDAVNKGLDAMAAKVKPGANSTDVSWEELRDTEWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            YEAVIRVNSQSGKGGVAYIMK DHGL++PR +Q+EFS  +Q +++ EGGE+    MWD+
Sbjct: 423 DYEAVIRVNSQSGKGGVAYIMKTDHGLQIPRSMQVEFSAVVQNVTDAEGGEVNSKAMWDI 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F  EYL    P+E+I  RV  A+ +    SI A +  NG++  + G GNGPLAA+ +AL 
Sbjct: 483 FATEYLERTAPVEQIALRVENAQTENEDASITAELIHNGKDVTVDGHGNGPLAAYANALE 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
            +G+ V + +Y++H                 V+G   WGVGIA SIT ASL+AV SAVNR
Sbjct: 543 KLGIDVEIQEYNQHARTSGDDAEAAAYVLAEVNGRKVWGVGIAGSITYASLKAVTSAVNR 602

Query: 604 AM 605
           A+
Sbjct: 603 AL 604


>tr|C8NXJ3|C8NXJ3_9CORY Tax_Id=585529 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium genitalium ATCC 33030]
          Length = 612

 Score =  757 bits (1954), Expect = 0.0
 Identities = 383/602 (63%), Positives = 442/602 (73%), Gaps = 8/602 (1%)

Query: 12  PADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P+D+  SAPS I KP GP + GQP WN QR + MP  RY  FA+EVE I L DRTWPD+ 
Sbjct: 3   PSDSQISAPSEIRKPNGPRNEGQPAWNMQRGSQMPADRYLSFAQEVEDITLPDRTWPDKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  KRRMF LLV MGYKEIEVGFPSASQTDF+FVRE
Sbjct: 63  ITVAPQWCAVDLRDGNQALIDPMSPERKRRMFKLLVEMGYKEIEVGFPSASQTDFNFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II +G IP+DVTIQVL Q R  LI RTFEAC  A RVIVHFYNSTS LQR VVFR D+  
Sbjct: 123 IIEEGMIPEDVTIQVLVQAREHLIRRTFEACAGAPRVIVHFYNSTSKLQREVVFRKDRPA 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K +ATD A      A  YP T WR+EYSPES+TGTEL++A +VCDAV ++++ TP+NP+
Sbjct: 183 IKKLATDAAELIKTIAKDYPDTQWRWEYSPESFTGTELDFAVEVCDAVVDIMEATPENPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLPATVEM TPNVYADSIEWM RN A R+S+I+SLHPHNDRG  VAAAELGY AGADR
Sbjct: 243 IINLPATVEMITPNVYADSIEWMHRNFAKRDSIIMSLHPHNDRGEGVAAAELGYMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNV L+TLGLN+ ++GVDPQIDFS+I  IR TVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVDLITLGLNMLTQGVDPQIDFSDIAGIRETVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQM-------KIXXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           GDLV+TAFSGSHQDAINKGLD +                     +W+VPYLPIDP+DVGR
Sbjct: 363 GDLVFTAFSGSHQDAINKGLDALAQKVRPGASSTEVAWEDLRETVWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            YEAVIRVNSQSGKGGVAYIMK DHG+++P+ +Q EFS  +Q I++ EGGE+    MWDV
Sbjct: 423 NYEAVIRVNSQSGKGGVAYIMKTDHGIDMPKEMQAEFSSVVQAITDSEGGEVNSKNMWDV 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F  EYL    PLE +   V+AAE D    ++ A    NGE  EI+G GNGP+AAF  AL 
Sbjct: 483 FAGEYLDVDTPLELVSLHVDAAESDDDEATVTAGAVYNGETKEITGSGNGPIAAFASALR 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
            +GL+  V DY +                  V G  AWGVGIA S T AS++A+VSAVNR
Sbjct: 543 SLGLEYEVRDYRQQARTAGGDADAACFIYSDVDGSEAWGVGIAGSTTRASIKAMVSAVNR 602

Query: 604 AM 605
            +
Sbjct: 603 GL 604


>tr|C8X8C8|C8X8C8_NAKMY Tax_Id=479431 SubName:
           Full=2-isopropylmalate synthase;[Nakamurella
           multipartita]
          Length = 598

 Score =  756 bits (1953), Expect = 0.0
 Identities = 388/588 (65%), Positives = 436/588 (74%), Gaps = 6/588 (1%)

Query: 19  APS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVIDCAPLW 77
           APS +  P G    GQ  +N QR ++MP  RY PFA    PI L DRTWP +VI  AP W
Sbjct: 5   APSRLRTPAGDIPAGQAAYNRQRPSAMPTGRYTPFA----PIDLPDRTWPSKVITKAPQW 60

Query: 78  CAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIITDGTI 137
           CAVDLRDGNQALIDPM+P  KRRMF+LLV+MG+KEIEVGFP+ASQTDFDFVREII    I
Sbjct: 61  CAVDLRDGNQALIDPMTPARKRRMFNLLVQMGFKEIEVGFPAASQTDFDFVREIIEQDAI 120

Query: 138 PDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVKAIATD 197
           P DV IQVLTQ RPELI RTFEA E A   +VH YNSTS LQRRVVF  D+  ++ IATD
Sbjct: 121 PSDVRIQVLTQARPELIARTFEAVEGAPAALVHLYNSTSTLQRRVVFGLDRVGIRRIATD 180

Query: 198 GARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIFNLPAT 257
           GA +    A KYP T WRFEYSPESYTGTELEYA +VC+AV  + QPT  NP++ NLPAT
Sbjct: 181 GAEEVARWAEKYPDTDWRFEYSPESYTGTELEYAVEVCNAVSAIWQPTEQNPMVVNLPAT 240

Query: 258 VEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIEGCLFG 317
           VEMATPNVYADSIEWM RNL  R  ++LSLHPHNDRGTAVAAAELGY AGADRIEGCLFG
Sbjct: 241 VEMATPNVYADSIEWMHRNLERRNGIVLSLHPHNDRGTAVAAAELGYMAGADRIEGCLFG 300

Query: 318 NGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGDLVYTA 377
           NGERTGNVCLVTLGLNLFS+G+DPQIDFS+IDEIRRTVEYCN+L V ERHPYGGDLVYTA
Sbjct: 301 NGERTGNVCLVTLGLNLFSQGIDPQIDFSDIDEIRRTVEYCNQLGVPERHPYGGDLVYTA 360

Query: 378 FSGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVNSQSGK 437
           FSGSHQDAI KG D ++              W VPYLPIDP+DVGR YEAVIRVNSQSGK
Sbjct: 361 FSGSHQDAIKKGFDHLRRDAEAAGVEVDEFTWAVPYLPIDPKDVGRNYEAVIRVNSQSGK 420

Query: 438 GGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPVQPLER 497
           GGVAYIMK +HGL+LPRRLQIEFSR +Q+ ++ EGGE+    M+  F EEYL    P++ 
Sbjct: 421 GGVAYIMKTEHGLDLPRRLQIEFSRVVQEHTDTEGGEVDAKTMFSYFAEEYLERTSPVKL 480

Query: 498 IKQRVNAAEE-DGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVLDYSE 556
           ++ R    EE D     I+ATV  NGEE   SG GNGP+AAF  AL  +G  V VLDY E
Sbjct: 481 VRTRFETPEEADHPFDKISATVVSNGEEVTASGAGNGPVAAFCQALTSIGHDVRVLDYVE 540

Query: 557 HXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNRA 604
           H                ++ G   WGVGI  SITTASL+AVVSAVNR+
Sbjct: 541 HALSAGGDARAAAYLECAIDGQVVWGVGIDSSITTASLKAVVSAVNRS 588


>tr|C3PJR0|C3PJR0_CORA7 Tax_Id=548476 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium aurimucosum]
          Length = 604

 Score =  749 bits (1935), Expect = 0.0
 Identities = 367/601 (61%), Positives = 442/601 (73%), Gaps = 8/601 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P D++ SAP  IT P GP +  QP WN QR +SMPV RY+ FA+EVEP+ L DRTWPD+ 
Sbjct: 3   PNDSFISAPREITTPAGPRNDNQPAWNKQRGSSMPVHRYQSFAEEVEPVSLPDRTWPDKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WC VDLRDGNQALIDPMSP  K RMFDLLV+MGYKEIEVGFPSASQTDFDFVRE
Sbjct: 63  ITVAPQWCVVDLRDGNQALIDPMSPERKHRMFDLLVKMGYKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II    IP+DVTIQVL Q R  LI RTFEAC+ A  VIVHFYNSTS LQRRVVFR D+  
Sbjct: 123 IIEGNKIPEDVTIQVLVQAREHLIRRTFEACQGAKNVIVHFYNSTSKLQRRVVFRKDRPA 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K +ATD A      A  YP T+WR+EYSPES+TGTEL++A +VCDAV ++++ TP+NP+
Sbjct: 183 IKKLATDAAELIKSIAKDYPDTNWRWEYSPESFTGTELDFAVEVCDAVVDIMEATPENPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM +PNVYAD IEWM RN A R+S+I+SLHPHNDRG  +AAAELGY AGADR
Sbjct: 243 IINLPSTVEMISPNVYADQIEWMHRNFARRDSIIMSLHPHNDRGEGIAAAELGYMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNV +VTLGLN+ ++GVDPQIDFS++ +IR TVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVDIVTLGLNMLTQGVDPQIDFSDLPKIRETVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQM-------KIXXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           G+LV+TAFSGSHQDAINKGLD +                      W+VPYLPIDP+DVGR
Sbjct: 363 GELVFTAFSGSHQDAINKGLDALAQEVRPGANNTEVSWEELQETTWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            Y+AVIRVNSQSGKGGVAYIMK DHG+ +PR +Q EFS  +Q +++ EGGE+    MWD+
Sbjct: 423 DYQAVIRVNSQSGKGGVAYIMKTDHGINMPRAMQAEFSSVVQAVTDAEGGEVNSKNMWDI 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F  E+L    PLE +  +V+ +  +     + AT+  NGE+  +SG+GNGP+AA+ +AL 
Sbjct: 483 FANEFLERTSPLELVSFQVDNSTTEDEDAKVTATIAFNGEKRIVSGIGNGPIAAYANALE 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
            VG+   V+DYS+                  V+G   WG GIA S T AS+ A+ SAVNR
Sbjct: 543 DVGIDFEVIDYSQQSRTSGDDAEAACYIAAEVNGAQVWGAGIAGSTTRASINAITSAVNR 602

Query: 604 A 604
           A
Sbjct: 603 A 603


>sp|Q8FU05|LEU1_COREF Tax_Id=152794 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthetase;[Corynebacterium efficiens]
          Length = 581

 Score =  744 bits (1922), Expect = 0.0
 Identities = 375/569 (65%), Positives = 429/569 (75%), Gaps = 7/569 (1%)

Query: 44  MPVFRYRPFAKEVEPIRLVDRTWPDRVIDCAPLWCAVDLRDGNQALIDPMSPICKRRMFD 103
           MPV RY PF  EVE I L DRTWPD+ I  AP WCAVDLRDGNQALIDPMSP  KRRMF+
Sbjct: 1   MPVKRYLPFEVEVEDITLPDRTWPDKKITQAPQWCAVDLRDGNQALIDPMSPERKRRMFE 60

Query: 104 LLVRMGYKEIEVGFPSASQTDFDFVREIITDGTIPDDVTIQVLTQCRPELIERTFEACEN 163
           LLV+MG+KEIEVGFPSASQTDFDFVREII    IPDDVTIQVL Q R  LI RTFEACE 
Sbjct: 61  LLVKMGFKEIEVGFPSASQTDFDFVREIIEKNMIPDDVTIQVLVQAREHLIRRTFEACEG 120

Query: 164 ASRVIVHFYNSTSILQRRVVFRADQATVKAIATDGARKCVEEAFKYPGTHWRFEYSPESY 223
           A  VIVHFYNSTSILQR VVFR ++  VK +ATD A      A  YP T+WR+EYSPESY
Sbjct: 121 AKNVIVHFYNSTSILQRDVVFRMNKDQVKTLATDAAELIKTIAQDYPDTNWRWEYSPESY 180

Query: 224 TGTELEYAKQVCDAVGEVIQPTPDNPIIFNLPATVEMATPNVYADSIEWMSRNLANRESV 283
           TGTE+EYAK+V DAV EV+ PTP+NPII NLPATVEM TPNVYADSIEWM RNL  R+S+
Sbjct: 181 TGTEVEYAKEVVDAVVEVMDPTPENPIIINLPATVEMITPNVYADSIEWMHRNLNRRDSI 240

Query: 284 ILSLHPHNDRGTAVAAAELGYHAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQI 343
           ILSLHPHNDRGT VAAAELGY AGADRIEGCLFGNGERTGNVCLVTL LN+ ++GVDPQ+
Sbjct: 241 ILSLHPHNDRGTGVAAAELGYMAGADRIEGCLFGNGERTGNVCLVTLALNMLTQGVDPQL 300

Query: 344 DFSNIDEIRRTVEYCNKLRVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKIXXXXXXXX 403
           DFS+I  IRRTVEYCN+LRV ERHPYGGDLV+TAFSGSHQDAINKGLD +          
Sbjct: 301 DFSDIKHIRRTVEYCNQLRVPERHPYGGDLVFTAFSGSHQDAINKGLDALAAKVKPGASS 360

Query: 404 XXXIL-------WQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLELPRRL 456
                       W+VPYLPIDP+DVGR YEAVIRVNSQSGKGGVAYIMK DHGL++PR +
Sbjct: 361 TEVAWEELRSTEWEVPYLPIDPKDVGRDYEAVIRVNSQSGKGGVAYIMKTDHGLKMPRSM 420

Query: 457 QIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAA 516
           Q+EFS  +Q +++ EGGE+   EMWD+F  EYL    P+E+I  RV  A+ +    +I A
Sbjct: 421 QVEFSAVVQNVTDAEGGEVNSKEMWDIFATEYLDRSAPVEQIALRVENAQTENDDATITA 480

Query: 517 TVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVH 576
            + ++GE   +SG GNGPLAA+ +AL  + + V + +YS+H                 V+
Sbjct: 481 ELVVDGENQTVSGRGNGPLAAYANALESLNIDVEIQEYSQHARTSGDDAEAAAYVLAEVN 540

Query: 577 GHTAWGVGIAPSITTASLRAVVSAVNRAM 605
           G   WGVGIA SIT ASL+AV SAVNRA+
Sbjct: 541 GRMVWGVGIAGSITYASLKAVTSAVNRAL 569


>tr|C0WHW2|C0WHW2_9CORY Tax_Id=525260 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium accolens ATCC 49725]
          Length = 605

 Score =  743 bits (1919), Expect = 0.0
 Identities = 367/602 (60%), Positives = 443/602 (73%), Gaps = 8/602 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P D++ SAP  IT P GPP  GQP WN QR +SMP  RY+PFA EVE I L DRTWP + 
Sbjct: 3   PNDSFISAPREITTPAGPPREGQPAWNKQRGSSMPFDRYQPFAVEVEDIDLPDRTWPGKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  K RMFDLLV+MGYKEIEVGFPSASQTDF+FVRE
Sbjct: 63  ITHAPQWCAVDLRDGNQALIDPMSPERKHRMFDLLVQMGYKEIEVGFPSASQTDFNFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II    IP+DVTIQVL Q R  LI RTFEAC  A  VIVHFYNSTS LQRRVVFR D+  
Sbjct: 123 IIEGDKIPEDVTIQVLVQAREHLIRRTFEACAGAKNVIVHFYNSTSKLQRRVVFRKDKPA 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K +ATD A      A  YP T+WR+EYSPES+TGTEL++A++VCD V  ++ P+P+NP+
Sbjct: 183 IKKLATDAAELIKSIAADYPDTNWRWEYSPESFTGTELDFAREVCDDVVAIMDPSPENPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM +PNVYADSIEWM RNLA R+S+++SLHPHNDRG  VAAAELGY AGADR
Sbjct: 243 IINLPSTVEMISPNVYADSIEWMDRNLARRDSILISLHPHNDRGEGVAAAELGYMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNV LVTLGLN+ ++GVDPQIDF+++ +IR TVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVDLVTLGLNMLTQGVDPQIDFTDLPKIRETVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKI-------XXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           G+LV+TAFSGSHQDAINKGLD +                     +W+VPYLPIDP+DVGR
Sbjct: 363 GELVFTAFSGSHQDAINKGLDALAATVRPEANSTDVSWEELRDAIWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            Y+AVIRVNSQSGKGGVAYIMK DHG+ +PR +Q EFS  +Q+I++ EGGE+    MWD+
Sbjct: 423 DYQAVIRVNSQSGKGGVAYIMKTDHGINMPRAMQAEFSTVVQEITDTEGGEVNSKNMWDI 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F  E+L    PL+     ++    +    ++ ATV  NG+E+E++G GNGP+AA+ +AL 
Sbjct: 483 FATEFLDRTTPLQLESFEIDNISAEDTDATVTATVTYNGKESEVTGTGNGPIAAYANALE 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
            +G+   V+DYS+                  V+ +  WG GIA S T AS+ A+ SAVNR
Sbjct: 543 SLGIDFDVIDYSQQSRSAGDDAEAACYIAADVNQNKVWGAGIAASTTRASINAITSAVNR 602

Query: 604 AM 605
           A+
Sbjct: 603 AL 604


>tr|C0XU51|C0XU51_9CORY Tax_Id=525263 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium lipophiloflavum DSM 44291]
          Length = 612

 Score =  743 bits (1917), Expect = 0.0
 Identities = 377/602 (62%), Positives = 435/602 (72%), Gaps = 8/602 (1%)

Query: 12  PADAYKSAPS-ITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P +   SAP+ I  P GP   GQP WN QR + MPV RY PFA+EVE I L DRTWPD+ 
Sbjct: 3   PLNPQFSAPNDIRTPSGPRWEGQPAWNKQRGSHMPVKRYLPFAQEVEDIILPDRTWPDKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  KRRMF+LLV+MGYKEIEVGFPSASQTDFDFVRE
Sbjct: 63  ITSAPQWCAVDLRDGNQALIDPMSPERKRRMFNLLVQMGYKEIEVGFPSASQTDFDFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II +  IP+DVTIQVL Q R  LI RTFEAC  A  VIVHFYNSTS LQR VVFR D+  
Sbjct: 123 IIENDMIPEDVTIQVLVQAREHLIRRTFEACAGAKNVIVHFYNSTSKLQREVVFRKDRPE 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K +ATD A      A  YP THWR+EYSPESYTGTEL++A +VCDAV +++  TPDNP+
Sbjct: 183 IKKLATDAAELIKTIAADYPDTHWRWEYSPESYTGTELDFALEVCDAVVDIMGATPDNPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM TPNVYADSIEWM RN A R+S+ILSLHPHNDRG  VAAAELGY AGADR
Sbjct: 243 IINLPSTVEMITPNVYADSIEWMHRNFAKRDSIILSLHPHNDRGEGVAAAELGYLAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNV LVTLGLN+ ++GVDPQIDFS+I+ IR  VEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVDLVTLGLNMLTQGVDPQIDFSDINRIREIVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQM-------KIXXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           GDLV+TAFSGSHQDA+NKGLD +                     +W+VPYLPIDP+DVGR
Sbjct: 363 GDLVFTAFSGSHQDAVNKGLDALAQKVRPGASSTDVRWEELRETVWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
           TYEAVIRVNSQSGKGGVAYIMK DHG+ +P+ +Q EFS  +Q I++ EGGE+    MWD+
Sbjct: 423 TYEAVIRVNSQSGKGGVAYIMKTDHGINMPKPMQPEFSAIVQNITDTEGGEVNSKNMWDI 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F   YL    PL+ +   V  A  +   +SI   V   GE   + G GNGP+AAF  AL 
Sbjct: 483 FAATYLDLDSPLDLVSYEVTGAVNEDEDSSIEVDVDYGGERHSLRGSGNGPVAAFAQALE 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
            +G+   V DY++                  V+G T WGVGIA S T ASL+A+VSAVNR
Sbjct: 543 SIGIDFEVQDYTQRSRSAGDDADAACYIRAEVNGATVWGVGIAGSTTRASLKAIVSAVNR 602

Query: 604 AM 605
            +
Sbjct: 603 GL 604


>tr|C2CS87|C2CS87_CORST Tax_Id=525268 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium striatum ATCC 6940]
          Length = 605

 Score =  740 bits (1910), Expect = 0.0
 Identities = 370/602 (61%), Positives = 442/602 (73%), Gaps = 8/602 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P D++ SAP  IT P GP    QP WN QR +SMPV RY  FA+EVE I+L DRTWPD+ 
Sbjct: 3   PNDSFISAPREITTPNGPFGENQPAWNKQRGSSMPVNRYLSFAEEVEDIQLPDRTWPDKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  K RMFDLLV+MGYKEIEVGFPSASQTDF+FVRE
Sbjct: 63  IISAPQWCAVDLRDGNQALIDPMSPQRKHRMFDLLVKMGYKEIEVGFPSASQTDFNFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II    IP+DVTIQVL Q R  LI RTFEACE A  VIVHFYNSTS LQRRVVFR D+  
Sbjct: 123 IIEQNKIPEDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSKLQRRVVFRKDRPA 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K +ATD A    E A  YP T+WR+EYSPES+TGTEL++A +VCDAV ++++ TP++P+
Sbjct: 183 IKKLATDAAALIKEIAKDYPDTNWRWEYSPESFTGTELDFAVEVCDAVVDIMEATPEHPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM TPNVYADSIEWM RN A R+S+ILSLHPHNDRG  +AAAELGY AGADR
Sbjct: 243 IINLPSTVEMITPNVYADSIEWMHRNFAKRDSIILSLHPHNDRGEGIAAAELGYLAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNV L+TLGLN+ ++GVDPQIDF+++  IR TVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVDLITLGLNMLTQGVDPQIDFTDLPAIRETVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQM-------KIXXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           G+LV+TAFSGSHQDAINKGLD +                     +W+VPYLPIDP+DVGR
Sbjct: 363 GELVFTAFSGSHQDAINKGLDALANEVRPGANNTEVSWDELRETVWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            Y+AVIRVNSQSGKGGVAYIMK DHG+ +PR +Q EFS  +Q++++ EGGE+    MWD+
Sbjct: 423 DYQAVIRVNSQSGKGGVAYIMKTDHGINMPRAMQAEFSAVVQEVTDTEGGEVNSKNMWDI 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F  E+L    PL      ++ +  D     + ATV+ NG E  ISG GNGP+AA+ +AL 
Sbjct: 483 FATEFLDREAPLAHKTFLIDNSPNDDSEAKVTATVEYNGSEHVISGHGNGPIAAYANALE 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
           H+G+   V++YS+                  V+G   WG GIA S T AS+ A+ SAVNR
Sbjct: 543 HLGIDFEVIEYSQQSRTAGDDAEAACYIAADVNGTQVWGAGIAGSTTRASIFAINSAVNR 602

Query: 604 AM 605
           A+
Sbjct: 603 AL 604


>tr|C2BKT1|C2BKT1_9CORY Tax_Id=525264 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium pseudogenitalium ATCC
           33035]
          Length = 607

 Score =  735 bits (1898), Expect = 0.0
 Identities = 367/604 (60%), Positives = 439/604 (72%), Gaps = 10/604 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P D++ SAP  IT P GP   GQP WN QR ++MP  RY+PFA EVE I L DRTWP + 
Sbjct: 3   PTDSFISAPRDITTPNGPRREGQPAWNKQRGSAMPHERYQPFAVEVEDIDLPDRTWPSKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  K RMFDLLV+MGYKEIEVGFPSASQTDF FVRE
Sbjct: 63  ITHAPQWCAVDLRDGNQALIDPMSPERKHRMFDLLVKMGYKEIEVGFPSASQTDFSFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II    IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTS LQRRVVFR D+  
Sbjct: 123 IIEGNKIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSKLQRRVVFRKDKPA 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K +AT+ A      A  YP T WR+EYSPES+TGTEL++A++VCD V E++ P+PDNP+
Sbjct: 183 IKKLATNAAALIKSIAADYPDTTWRWEYSPESFTGTELDFAREVCDEVVEIMDPSPDNPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM +PNVYADSIEWM RNLA RE ++LSLHPHNDRG  +AAAELG+ AGADR
Sbjct: 243 IINLPSTVEMISPNVYADSIEWMHRNLARREDILLSLHPHNDRGEGIAAAELGFMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNV L+TLGLN+ ++GVDPQIDFS++ +IR TVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVDLITLGLNMLTQGVDPQIDFSDLPQIRETVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKI-------XXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           G+LV+TAFSGSHQDA+NKGLD +                     +W+VPYLPIDP+DVGR
Sbjct: 363 GELVFTAFSGSHQDAVNKGLDALAATIRPGANNTEVSWEELREAIWEVPYLPIDPKDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            Y+AVIRVNSQSGKGGVAYIMK DHG+ +PR +Q EFS  +Q+I++ EGGE+    MWD+
Sbjct: 423 DYQAVIRVNSQSGKGGVAYIMKTDHGINMPRAMQAEFSTVVQEITDSEGGEVNSKNMWDI 482

Query: 484 FFEEYLSPVQPL--ERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDA 541
           F  E+L    PL  E      + A +  G  ++ ATV   GE++ +SG GNGP+AA+ +A
Sbjct: 483 FATEFLDRETPLVVEAFHIDNSPAADGDGDVAVTATVAFRGEKSTVSGTGNGPIAAYANA 542

Query: 542 LGHVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAV 601
           L  +G+   V++YS+                  V+    WG GIA S T AS+ A+ SAV
Sbjct: 543 LESLGIDFEVMEYSQQSRSAGDDAEAACYIAADVNQSKVWGAGIAGSTTRASINAINSAV 602

Query: 602 NRAM 605
           NRA+
Sbjct: 603 NRAL 606


>tr|C6R7K4|C6R7K4_9CORY Tax_Id=553206 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium tuberculostearicum SK141]
          Length = 605

 Score =  735 bits (1897), Expect = 0.0
 Identities = 366/602 (60%), Positives = 437/602 (72%), Gaps = 8/602 (1%)

Query: 12  PADAYKSAP-SITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRV 70
           P D++ SAP  IT P GP   GQP WN QR ++MP  RY+PFA EVE I L DRTWP + 
Sbjct: 3   PTDSFISAPRDITTPNGPRREGQPAWNKQRGSAMPHERYQPFAVEVEDIDLPDRTWPSKK 62

Query: 71  IDCAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 130
           I  AP WCAVDLRDGNQALIDPMSP  K RMFDLLV+MGYKEIEVGFPSASQTDF FVRE
Sbjct: 63  ITHAPQWCAVDLRDGNQALIDPMSPERKHRMFDLLVKMGYKEIEVGFPSASQTDFSFVRE 122

Query: 131 IITDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQAT 190
           II    IPDDVTIQVL Q R  LI RTFEACE A  VIVHFYNSTS LQRRVVFR D+  
Sbjct: 123 IIEGNKIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSKLQRRVVFRKDKPA 182

Query: 191 VKAIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPI 250
           +K +AT+ A      A  YP T WR+EYSPES+TGTEL++A++VCD V E++ P+PDNP+
Sbjct: 183 IKKLATNAAALIKSIAADYPDTTWRWEYSPESFTGTELDFAREVCDEVVEIMDPSPDNPM 242

Query: 251 IFNLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADR 310
           I NLP+TVEM +PNVYADSIEWM RNLA RE ++LSLHPHNDRG  +AAAELG+ AGADR
Sbjct: 243 IINLPSTVEMISPNVYADSIEWMHRNLARREDILLSLHPHNDRGEGIAAAELGFMAGADR 302

Query: 311 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYG 370
           IEGCLFGNGERTGNV L+TLGLN+ ++GVDPQIDFS++ +IR TVEYCN+LRV ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVDLITLGLNMLTQGVDPQIDFSDLPQIRETVEYCNQLRVPERHPYG 362

Query: 371 GDLVYTAFSGSHQDAINKGLDQMKI-------XXXXXXXXXXXILWQVPYLPIDPRDVGR 423
           G+LV+TAFSGSHQDAINKGLD +                     +W+VPYLPIDP DVGR
Sbjct: 363 GELVFTAFSGSHQDAINKGLDALAATIRPGANNTEVSWEELREAIWEVPYLPIDPMDVGR 422

Query: 424 TYEAVIRVNSQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDV 483
            Y+AVIRVNSQSGKGGVAYIMK DHG+ +PR +Q EFS  +Q+I++ EGGE+    MWD+
Sbjct: 423 DYQAVIRVNSQSGKGGVAYIMKTDHGINMPRAMQAEFSTVVQEITDSEGGEVNSKNMWDI 482

Query: 484 FFEEYLSPVQPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALG 543
           F  E+L    PL      ++ +    G  ++ ATV   GE++ +SG GNGP+AA+ +AL 
Sbjct: 483 FATEFLDRETPLVVEAFHIDNSPAADGDVAVTATVAFRGEKSTVSGTGNGPIAAYANALE 542

Query: 544 HVGLQVAVLDYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
            +G+   V++YS+                  V+    WG GIA S T AS+ A+ SAVNR
Sbjct: 543 SLGIDFEVMEYSQQSRSAGDDAEAACYIAADVNQSKVWGAGIAGSTTRASINAINSAVNR 602

Query: 604 AM 605
           A+
Sbjct: 603 AL 604


>tr|C1RP27|C1RP27_9CELL Tax_Id=446466 SubName:
           Full=2-isopropylmalate synthase;[Cellulomonas flavigena
           DSM 20109]
          Length = 595

 Score =  717 bits (1852), Expect = 0.0
 Identities = 361/591 (61%), Positives = 440/591 (74%), Gaps = 9/591 (1%)

Query: 19  APSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVIDCAPLWC 78
           +P+   P+ P    +   NPQ+ + MP  RYRPF +++  + L DRTWPD+ I+ AP WC
Sbjct: 5   SPTTPAPVTPAPAAER--NPQQPSGMPFHRYRPFHEQIR-VELPDRTWPDKRIERAPRWC 61

Query: 79  AVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIITDGTIP 138
           AVDLRDGNQALI+PMSP  K  MF+LLV MGYKEIEVGFPSASQTD+DFVR +I +G IP
Sbjct: 62  AVDLRDGNQALIEPMSPARKLEMFELLVDMGYKEIEVGFPSASQTDYDFVRMLIEEGRIP 121

Query: 139 DDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVKAIATDG 198
           DDV IQVLTQ R  LIERT+EA   A + IVH YNSTS+LQR VVFRAD+  +  IA  G
Sbjct: 122 DDVVIQVLTQAREHLIERTYEAIAGAKQAIVHLYNSTSVLQREVVFRADEDGIADIAVSG 181

Query: 199 ARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIFNLPATV 258
           AR C +     P T   +EYSPESYTGTELEYA +VC+AV +V++PTP+ P+I NLPATV
Sbjct: 182 ARFCKKYEELVPDTEVFYEYSPESYTGTELEYAVRVCNAVLDVLEPTPERPVIINLPATV 241

Query: 259 EMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIEGCLFGN 318
           EMATPNVYADSIEWMSR+L +RESV+LSLHPHNDRGTAVAAAELGY AGADRIEGCLFGN
Sbjct: 242 EMATPNVYADSIEWMSRHLHHRESVVLSLHPHNDRGTAVAAAELGYLAGADRIEGCLFGN 301

Query: 319 GERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGDLVYTAF 378
           GERTGNV LVTLGLNLFS+G+DPQIDFS+ID +RRTVE CN++ VHERHPYGGDLV+TAF
Sbjct: 302 GERTGNVDLVTLGLNLFSQGIDPQIDFSDIDRVRRTVERCNQMPVHERHPYGGDLVFTAF 361

Query: 379 SGSHQDAINKGLDQMKIXXXXXXXXXXXILWQVPYLPIDPRDVGRTYEAVIRVNSQSGKG 438
           SGSHQDAI KGLD +++           + W VPYLPIDP+DVGR+YEA+IRVNSQSGKG
Sbjct: 362 SGSHQDAIKKGLDALEVRATAAGKGVDDVEWAVPYLPIDPKDVGRSYEAIIRVNSQSGKG 421

Query: 439 GVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYL-----SPVQ 493
           G++Y++K++  L+LPRRLQIEFS+ +Q+ ++  G E+T  E+W +F +EYL      P++
Sbjct: 422 GISYLLKSEKDLDLPRRLQIEFSQVVQRHTDQHGTEVTADELWSIFSDEYLPATPGGPLE 481

Query: 494 PLERIKQR-VNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVL 552
           P  R   R   A   +GG  ++   +   G E  +SG GNGP+AAF+ AL   G+ VAVL
Sbjct: 482 PWGRFALRGTRATSTEGGQDTLEVDLVDRGVEKTLSGTGNGPVAAFVAALRTAGVDVAVL 541

Query: 553 DYSEHXXXXXXXXXXXXXXXXSVHGHTAWGVGIAPSITTASLRAVVSAVNR 603
           DY+EH                ++     WGVGI PSITTASL+A+VSAVNR
Sbjct: 542 DYAEHALSAGGDATAAAYVECAIGDDILWGVGIDPSITTASLKAIVSAVNR 592


  Database: Amellifera_nr
    Posted date:  Jan 15, 2010  5:10 AM
  Number of letters in database: 3,808,957,724
  Number of sequences in database:  11,153,314
  
Lambda     K      H
   0.319    0.135    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11153314
Number of Hits to DB: 4,442,694,431
Number of extensions: 187206200
Number of successful extensions: 471388
Number of sequences better than 10.0: 2886
Number of HSP's gapped: 468359
Number of HSP's successfully gapped: 2935
Length of query: 607
Length of database: 3,808,957,724
Length adjustment: 144
Effective length of query: 463
Effective length of database: 2,202,880,508
Effective search space: 1019933675204
Effective search space used: 1019933675204
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 83 (36.6 bits)