BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= ML2341c (732 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,153,314 sequences; 3,808,957,724 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|Q9CB72|Q9CB72_MYCLE Tax_Id=1769 SubName: Full=Possible regula... 1321 0.0 tr|B8ZT28|B8ZT28_MYCLB Tax_Id=561304 SubName: Full=Possible regu... 1321 0.0 tr|O69511|O69511_MYCLE Tax_Id=1769 (MLCB2407.09)SubName: Full=Pu... 1321 0.0 tr|B2HLD0|B2HLD0_MYCMM Tax_Id=216594 SubName: Full=Membrane-anch... 882 0.0 tr|B2HLC7|B2HLC7_MYCMM Tax_Id=216594 SubName: Full=Membrane-anch... 849 0.0 tr|A3PVY9|A3PVY9_MYCSJ Tax_Id=164757 SubName: Full=Adenylyl cycl... 772 0.0 tr|A0QP05|A0QP05_MYCS2 Tax_Id=246196 SubName: Full=Adenylate and... 759 0.0 tr|Q1BCN4|Q1BCN4_MYCSS Tax_Id=164756 SubName: Full=Adenylate/gua... 743 0.0 tr|A1UCA9|A1UCA9_MYCSK Tax_Id=189918 SubName: Full=Adenylyl cycl... 743 0.0 tr|A3PVY7|A3PVY7_MYCSJ Tax_Id=164757 SubName: Full=Adenylyl cycl... 695 0.0 tr|A1T6C4|A1T6C4_MYCVP Tax_Id=350058 SubName: Full=Adenylyl cycl... 512 e-143 tr|Q1BCN6|Q1BCN6_MYCSS Tax_Id=164756 SubName: Full=Adenylate/gua... 289 8e-76 tr|A1UCA7|A1UCA7_MYCSK Tax_Id=189918 SubName: Full=Putative aden... 289 8e-76 tr|Q46RQ2|Q46RQ2_RALEJ Tax_Id=264198 SubName: Full=Adenylyl cycl... 283 5e-74 tr|B8FAC8|B8FAC8_DESAA Tax_Id=439235 SubName: Full=Adenylate/gua... 276 9e-72 tr|A4Z0R3|A4Z0R3_BRASO Tax_Id=114615 SubName: Full=Putative Aden... 275 2e-71 tr|Q0K118|Q0K118_RALEH Tax_Id=381666 SubName: Full=ATP synthase ... 273 5e-71 tr|B3RAH8|B3RAH8_CUPTR Tax_Id=164546 SubName: Full=Putative aden... 272 1e-70 tr|Q0JZ82|Q0JZ82_RALEH Tax_Id=381666 SubName: Full=Two domain pr... 268 1e-69 tr|Q46V35|Q46V35_RALEJ Tax_Id=264198 SubName: Full=Adenylate/gua... 264 4e-68 tr|B5WAJ2|B5WAJ2_9BURK Tax_Id=516466 SubName: Full=Adenylate/gua... 261 2e-67 tr|Q39P44|Q39P44_BURS3 Tax_Id=269483 SubName: Full=Adenylate/gua... 258 2e-66 tr|Q46MZ4|Q46MZ4_RALEJ Tax_Id=264198 SubName: Full=Adenylate/gua... 258 3e-66 tr|B1Z5L4|B1Z5L4_BURA4 Tax_Id=398577 SubName: Full=Adenylate/gua... 252 1e-64 tr|Q0B393|Q0B393_BURCM Tax_Id=339670 SubName: Full=Adenylate/gua... 251 2e-64 tr|B1FEB2|B1FEB2_9BURK Tax_Id=396596 SubName: Full=Adenylate/gua... 251 2e-64 tr|A9B3B1|A9B3B1_HERA2 Tax_Id=316274 SubName: Full=Adenylate/gua... 250 4e-64 tr|Q89K68|Q89K68_BRAJA Tax_Id=375 SubName: Full=Bll5043 protein;... 249 7e-64 tr|A8L7N2|A8L7N2_FRASN Tax_Id=298653 SubName: Full=Adenylate/gua... 248 2e-63 tr|Q46SE1|Q46SE1_RALEJ Tax_Id=264198 SubName: Full=Adenylyl cycl... 247 4e-63 tr|A6UFJ6|A6UFJ6_SINMW Tax_Id=366394 SubName: Full=Adenylyl cycl... 247 4e-63 tr|B1T4T0|B1T4T0_9BURK Tax_Id=396597 SubName: Full=Adenylate/gua... 246 6e-63 tr|Q2K8B4|Q2K8B4_RHIEC Tax_Id=347834 SubName: Full=Putative aden... 245 2e-62 tr|B3Q0E9|B3Q0E9_RHIE6 Tax_Id=491916 SubName: Full=Putative aden... 243 9e-62 tr|Q98GL0|Q98GL0_RHILO Tax_Id=381 SubName: Full=Mlr3277 protein;... 240 6e-61 tr|Q2JH00|Q2JH00_FRASC Tax_Id=106370 SubName: Full=Adenylate/gua... 239 7e-61 tr|C6AXV1|C6AXV1_RHILS Tax_Id=395491 SubName: Full=Adenylate/gua... 239 7e-61 tr|B5ZPV2|B5ZPV2_RHILW Tax_Id=395492 SubName: Full=Adenylate/gua... 236 6e-60 tr|Q92YL0|Q92YL0_RHIME Tax_Id=382 (cyaI3)SubName: Full=CyaI3 ade... 233 5e-59 tr|Q1MGI8|Q1MGI8_RHIL3 Tax_Id=216596 SubName: Full=Putative aden... 232 2e-58 tr|C4CPA9|C4CPA9_9CHLR Tax_Id=479434 SubName: Full=Adenylate/gua... 232 2e-58 tr|Q89HN2|Q89HN2_BRAJA Tax_Id=375 SubName: Full=Bll5958 protein;... 229 1e-57 tr|Q0RUJ9|Q0RUJ9_FRAAA Tax_Id=326424 SubName: Full=Putative aden... 225 2e-56 tr|A8LF50|A8LF50_FRASN Tax_Id=298653 SubName: Full=Adenylate/gua... 222 1e-55 tr|A6UA40|A6UA40_SINMW Tax_Id=366394 SubName: Full=Sterile alpha... 221 4e-55 tr|Q92Y97|Q92Y97_RHIME Tax_Id=382 (cyaI4)SubName: Full=CyaI4 ade... 219 1e-54 tr|Q68M96|Q68M96_RHIME Tax_Id=382 (rtsD)SubName: Full=RtsD;[Rhiz... 219 1e-54 tr|Q2J511|Q2J511_FRASC Tax_Id=106370 SubName: Full=Adenylate/gua... 215 2e-53 tr|Q3A5C7|Q3A5C7_PELCD Tax_Id=338963 SubName: Full=Predicted ATP... 214 4e-53 tr|Q89CC0|Q89CC0_BRAJA Tax_Id=375 SubName: Full=Bll7877 protein;... 211 2e-52 >tr|Q9CB72|Q9CB72_MYCLE Tax_Id=1769 SubName: Full=Possible regulatory protein;[Mycobacterium leprae] Length = 732 Score = 1321 bits (3420), Expect = 0.0 Identities = 691/732 (94%), Positives = 691/732 (94%) Query: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE Sbjct: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 Query: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA Sbjct: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 Query: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV Sbjct: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 Query: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL Sbjct: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 Query: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF Sbjct: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 Query: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXX 360 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQ GIADPAVE Sbjct: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLLGIADPAVELPRLDPDA 360 Query: 361 XXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 INVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY Sbjct: 361 RRRRLTALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 Query: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR Sbjct: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 Query: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG Sbjct: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 Query: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSD Sbjct: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRARLHRRL 600 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 PHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK Sbjct: 601 AAAIEARAPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 Query: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG 720 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG Sbjct: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG 720 Query: 721 PAIDHVYQDRLH 732 PAIDHVYQDRLH Sbjct: 721 PAIDHVYQDRLH 732 >tr|B8ZT28|B8ZT28_MYCLB Tax_Id=561304 SubName: Full=Possible regulatory protein;[Mycobacterium leprae] Length = 732 Score = 1321 bits (3420), Expect = 0.0 Identities = 691/732 (94%), Positives = 691/732 (94%) Query: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE Sbjct: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 Query: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA Sbjct: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 Query: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV Sbjct: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 Query: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL Sbjct: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 Query: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF Sbjct: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 Query: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXX 360 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQ GIADPAVE Sbjct: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLLGIADPAVELPRLDPDA 360 Query: 361 XXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 INVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY Sbjct: 361 RRRRLTALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 Query: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR Sbjct: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 Query: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG Sbjct: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 Query: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSD Sbjct: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRARLHRRL 600 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 PHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK Sbjct: 601 AAAIEARAPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 Query: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG 720 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG Sbjct: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG 720 Query: 721 PAIDHVYQDRLH 732 PAIDHVYQDRLH Sbjct: 721 PAIDHVYQDRLH 732 >tr|O69511|O69511_MYCLE Tax_Id=1769 (MLCB2407.09)SubName: Full=Putative uncharacterized protein MLCB2407.09;[Mycobacterium leprae] Length = 787 Score = 1321 bits (3420), Expect = 0.0 Identities = 691/732 (94%), Positives = 691/732 (94%) Query: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE Sbjct: 56 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 115 Query: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA Sbjct: 116 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 175 Query: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV Sbjct: 176 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 235 Query: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL Sbjct: 236 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 295 Query: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF Sbjct: 296 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 355 Query: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXX 360 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQ GIADPAVE Sbjct: 356 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLLGIADPAVELPRLDPDA 415 Query: 361 XXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 INVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY Sbjct: 416 RRRRLTALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 475 Query: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR Sbjct: 476 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 535 Query: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG Sbjct: 536 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 595 Query: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSD Sbjct: 596 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRARLHRRL 655 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 PHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK Sbjct: 656 AAAIEARAPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 715 Query: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG 720 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG Sbjct: 716 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVG 775 Query: 721 PAIDHVYQDRLH 732 PAIDHVYQDRLH Sbjct: 776 PAIDHVYQDRLH 787 >tr|B2HLD0|B2HLD0_MYCMM Tax_Id=216594 SubName: Full=Membrane-anchored adenylyl cyclase;[Mycobacterium marinum] Length = 1058 Score = 882 bits (2278), Expect = 0.0 Identities = 472/733 (64%), Positives = 540/733 (73%), Gaps = 2/733 (0%) Query: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEA-ETPAEYKQVTVLFADVVGSMDIAAAVGL 59 MT L C +CG + A+FC CG+PV A + AEYKQVTVLFADVV SMDIAAA+G Sbjct: 1 MTPVLACRSCGTQPLENARFCHGCGAPVAAAADAHAEYKQVTVLFADVVHSMDIAAALGA 60 Query: 60 ERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEK 119 ERLREIMTELV+RAA V++RYGGTVDKFTGDGIMA+FGAP ALEDHALRACLAALGVQ++ Sbjct: 61 ERLREIMTELVNRAAVVVQRYGGTVDKFTGDGIMAVFGAPAALEDHALRACLAALGVQDE 120 Query: 120 ARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGV 179 A+RLA EV RDGV LQLRVGLNSGQV+ GEIG+ ALGYTAVG QVG+AQRME+VA P Sbjct: 121 AKRLAGEVDRRDGVVLQLRVGLNSGQVVAGEIGTGALGYTAVGEQVGLAQRMEAVAAPET 180 Query: 180 VMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWE 239 VML ESTARLVE AVLG PQ V IKG E AVPA +LL V + + + +TLVGREWE Sbjct: 181 VMLGESTARLVEGAAVLGEPQLVHIKGVEAAVPAWQLLGVVDQYWQSGPAPATLVGREWE 240 Query: 240 LATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVA 299 L TL MLDRSI GRGSVV LVG AGIGKTRL EA Q+AK L V VFS FCESHATD+ Sbjct: 241 LDTLTTMLDRSIAGRGSVVTLVGRAGIGKTRLAREAAQVAKNLGVTVFSTFCESHATDIP 300 Query: 300 FDVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXX 359 F V +L+RA AQ+S LDD +AR RVR +PD D Q GIADP VE Sbjct: 301 FRAVTRLLRAAAQVSRLDDATARVRVRAIVPDGDPQDLLLLYDLLGIADPQVELPKIAPE 360 Query: 360 XXXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPE 419 IN QLA ++PAV+V+ED HW+DE S+SM+A+FL VIPQT SM LVTYRP+ Sbjct: 361 ARRRRLTALINAVQLARAQPAVYVIEDAHWMDEASESMVAEFLTVIPQTHSMVLVTYRPD 420 Query: 420 YHGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEIT 479 Y GALR V GAQ IA+ PLSD ETS L+AELLG SV QI E+I RAAGNPFFA+EI Sbjct: 421 YRGALRGVRGAQSIALGPLSDAETSALIAELLGPAPSVAQIAEIIATRAAGNPFFAEEII 480 Query: 480 RELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRF 539 RELAER VL GERGRY C+ + + VPATLQATI ARIDRLSP AKQ L AAAVIG RF Sbjct: 481 RELAERRVLVGERGRYTCTAEADDAIVPATLQATIGARIDRLSPAAKQTLSAAAVIGSRF 540 Query: 540 GSDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXX 599 ++LL LGID ++ELI A LVDQVRFT P EY FRHPLI TVAYESQLKS Sbjct: 541 STELLIGLGIDPPIEELISAELVDQVRFTEPAEYVFRHPLIHTVAYESQLKSARAQMHRR 600 Query: 600 XXXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHAT 659 P S DQ+A LIAEHLEAAG+ HAAYGW +RAAAWATN+D+ AA +SWE A Sbjct: 601 LAAVIEARVPESADQYAALIAEHLEAAGESHAAYGWQVRAAAWATNRDIAAAHLSWERAR 660 Query: 660 KIADALTAEDPHRAAMCIAPRTRLCGIAWRGRFN-SSSGFDEVRQLCNATGDKAPLAVAT 718 KIADAL +DP+RAAM IAPRT LCGIA+R + + + F+E+R+LC A GDKA L++ Sbjct: 661 KIADALPVDDPNRAAMRIAPRTMLCGIAFRIHIDVAGARFEELRELCAAAGDKASLSIGM 720 Query: 719 VGPAIDHVYQDRL 731 G IDH+ R+ Sbjct: 721 AGLVIDHLQHARM 733 >tr|B2HLC7|B2HLC7_MYCMM Tax_Id=216594 SubName: Full=Membrane-anchored adenylyl cyclase;[Mycobacterium marinum] Length = 1056 Score = 849 bits (2194), Expect = 0.0 Identities = 447/733 (60%), Positives = 532/733 (72%), Gaps = 2/733 (0%) Query: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 MT VC ACG E A+FC ECG+P+ A+T AEYKQVTVLFADV SMDIAAAVG E Sbjct: 1 MTPVTVCRACGVEPLENARFCHECGAPIGAADTRAEYKQVTVLFADVAHSMDIAAAVGPE 60 Query: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 RLREIM ELV+RA+ V++RY G VDKFTGDG+MA+FGAP ALEDHALRACLAAL +Q++ Sbjct: 61 RLREIMAELVTRASVVVQRYAGRVDKFTGDGVMALFGAPAALEDHALRACLAALDIQDEV 120 Query: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 RLAA++ DGV+L+LR+GLNSG+VI G IG +ALGYTAVG QVGMAQRMES+AP G V Sbjct: 121 ARLAADISRTDGVELRLRIGLNSGEVITGGIGPTALGYTAVGEQVGMAQRMESIAPVGGV 180 Query: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 M+S++TARLV+ +LGAPQ V++KG V AR L Q T +ESTLVGR WE+ Sbjct: 181 MVSDTTARLVDGVVLLGAPQRVQVKGM-GTVSARELRSATAQHQRTDSAESTLVGRGWEV 239 Query: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 A ++ MLDR+I GRGSVVG+ GP GIGK+RLV EA+ LA+ V V +CESHA DV F Sbjct: 240 AAVSTMLDRAIHGRGSVVGVTGPVGIGKSRLVREAIGLARSRGVTVVHTYCESHAADVPF 299 Query: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXX 360 V+ +L+RAV Q SGLDD +ARARVR+++PDA GIA P E Sbjct: 300 RVMTRLLRAVGQASGLDDEAARARVRDRVPDAQLPDLLLLDDLLGIAAPGAELPRIDPDA 359 Query: 361 XXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 IN +QLA + P VFV+EDVHWIDE S+SMLADFL V+ QT S+ L TYRPEY Sbjct: 360 RRRRLTGLINASQLARTEPVVFVLEDVHWIDEASESMLADFLTVMLQTPSLVLFTYRPEY 419 Query: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 GAL+ V GAQ IA+APL+D + STLVAELLG D SV IG +I+ERAAGNP FA+E+TR Sbjct: 420 RGALQLVPGAQTIALAPLTDADVSTLVAELLGQDPSVATIGRVISERAAGNPLFAEEMTR 479 Query: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 ELAERGVLTGERG Y C TDVAE+ VPAT+QA I ARIDRLSP AKQ L AAAV+G RF Sbjct: 480 ELAERGVLTGERGSYQCRTDVAEIRVPATVQAAIGARIDRLSPAAKQTLSAAAVVGSRFS 539 Query: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 SDLL LGI+ +DEL+DA+L+DQVRFT EYAFRHPL+RTVAYE+QL++D Sbjct: 540 SDLLIGLGIEPCIDELLDADLIDQVRFTTRAEYAFRHPLVRTVAYEAQLRADRAQLHRRL 599 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 D HA LIAEH EAAGDL AAY WHMRA WA N+D+ AAR+SWE AT+ Sbjct: 600 AQALENAEADPGDHHAALIAEHFEAAGDLAAAYRWHMRAGKWALNRDIAAARLSWERATR 659 Query: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFN-SSSGFDEVRQLCNATGDKAPLAVATV 719 I+DAL A+ P R+ IAPRT LCG AWR N S + F E+R+LC A DK LA+AT Sbjct: 660 ISDALPADTPDRSVKRIAPRTMLCGYAWRVHVNISDAHFAELRELCLAAADKTSLAIATA 719 Query: 720 GPAIDHVYQDRLH 732 G +D +YQ R+H Sbjct: 720 GLVMDRIYQARIH 732 >tr|A3PVY9|A3PVY9_MYCSJ Tax_Id=164757 SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase;[Mycobacterium sp.] Length = 1053 Score = 772 bits (1993), Expect = 0.0 Identities = 407/721 (56%), Positives = 497/721 (68%), Gaps = 2/721 (0%) Query: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 MT + C CG E A+FC CG+PV + AEYKQVTVLFADVV SMD+AAAVG E Sbjct: 1 MTASTACRTCGTEYLDGARFCHGCGAPVGQPAAHAEYKQVTVLFADVVRSMDVAAAVGAE 60 Query: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 RLREIM +LV+R++ V++RYGGTVDKFTGDGIMA+FGAP ALEDHA+RACLAALG+Q++A Sbjct: 61 RLREIMADLVNRSSAVVQRYGGTVDKFTGDGIMAVFGAPIALEDHAIRACLAALGIQQQA 120 Query: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 +LA V DG LQLR+GLNSGQVIVG+I S ALGYTAVG VG AQRMESVA PG V Sbjct: 121 AQLATTVERLDGAALQLRIGLNSGQVIVGDIASPALGYTAVGEHVGWAQRMESVAAPGGV 180 Query: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 +LS+STARLVE AVLGAP+ V +KG + AV ARRL+ +A P E LVGR WE+ Sbjct: 181 LLSDSTARLVEHVAVLGAPEKVSVKGCDRAVAARRLMGMAAPHAVAGRGEPRLVGRRWEM 240 Query: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 A +L+RSI G G+VV LVGP GIGK+R+ E A V+VF FCESH +DV F Sbjct: 241 AAAEGILERSIDGAGTVVALVGPPGIGKSRMAREIASAAATRGVDVFWSFCESHTSDVPF 300 Query: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXX 360 VV QL+R +A + GL D RAR+R + DAD Q I DP Sbjct: 301 HVVGQLLRTIAGLPGLPDELVRARLRARFDDADEQDLLLFEDLLEIRDPDAALPDIDPDA 360 Query: 361 XXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 + A ++ PA+++VED HWIDEVSD+M ADF+ VIPQT +M L+T+RP++ Sbjct: 361 RRRRLSRMVKAAAVSRGSPALYIVEDAHWIDEVSDAMAADFVTVIPQTHAMVLITHRPDF 420 Query: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 HGAL V GAQ + +APLS+ E++TL LLG D SV + + +RAAGNPFFA+EI R Sbjct: 421 HGALSRVPGAQTLTLAPLSEPESATLARALLGADPSVVDLAVTVAQRAAGNPFFAEEIVR 480 Query: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 +LAERG+L G RG Y C DVAE+ VPATLQATIAARIDRL PAK L AA+VIG RF Sbjct: 481 DLAERGLLHGRRGEYVCRVDVAEISVPATLQATIAARIDRLESPAKNTLCAASVIGMRFD 540 Query: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 +DLLAS+G+ VD L+ A L+DQV+FT EYAFRHPLIRTVAYESQL+SD Sbjct: 541 TDLLASMGVAPVVDGLLLAELIDQVKFTGHAEYAFRHPLIRTVAYESQLRSDRVALHRRL 600 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 P S+D++A LIAEHLEAAGD AAY WHMRAAAW+ +D+RAA VSWE A+ Sbjct: 601 ADAISRQEP-SIDENAALIAEHLEAAGDSRAAYEWHMRAAAWSQQRDIRAALVSWERASM 659 Query: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWR-GRFNSSSGFDEVRQLCNATGDKAPLAVATV 719 +ADAL A+ P + + IAPRT LC +R F+E+++LC GDKA +A+A Sbjct: 660 LADALPADTPGQLELRIAPRTLLCANGFRKHELAGGRRFEELQELCAVAGDKASVAIAMA 719 Query: 720 G 720 G Sbjct: 720 G 720 >tr|A0QP05|A0QP05_MYCS2 Tax_Id=246196 SubName: Full=Adenylate and Guanylate cyclase catalytic domain protein;[Mycobacterium smegmatis] Length = 1050 Score = 759 bits (1961), Expect = 0.0 Identities = 407/717 (56%), Positives = 491/717 (68%), Gaps = 2/717 (0%) Query: 5 LVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLRE 64 + C CG ELR A+FCD CG+ +V+ AEYKQVTVLFADVV SM +AAAVG ERLRE Sbjct: 2 VACGTCGTELRQGARFCDSCGTAIVDGSKHAEYKQVTVLFADVVDSMRLAAAVGAERLRE 61 Query: 65 IMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLA 124 I++ LVSR +GV+ YGGTVDKFTGDGIMA+FGAP ALEDHALRACLAAL +Q ++ RLA Sbjct: 62 ILSALVSRCSGVVGHYGGTVDKFTGDGIMALFGAPLALEDHALRACLAALDLQYESHRLA 121 Query: 125 AEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSE 184 E+ GV LQ+RVGLNSGQVI GE+ + GYTA+G QVGMAQRMESVAP G +M S+ Sbjct: 122 DELDLPAGVGLQIRVGLNSGQVIAGEMSAGGFGYTAIGEQVGMAQRMESVAPHGGIMCSD 181 Query: 185 STARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELATLA 244 +TARLVE + +LGAP+ +R+KG + V ARRLL A S+ TLVGR WEL T+A Sbjct: 182 TTARLVEDSVLLGAPEMLRVKGCDRPVAARRLL-AATNAAHGGRSDPTLVGRSWELNTIA 240 Query: 245 AMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVA 304 +LD ++ GRG +V +VGP GIGK+R+V E+++LA+ V VF +CESHA+DV F VV Sbjct: 241 GLLDEAVEGRGGIVSVVGPPGIGKSRMVRESIELARRRGVAVFYTYCESHASDVPFHVVV 300 Query: 305 QLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXX 364 L+R ++GLD +AR RVR +PDAD + GIADP V Sbjct: 301 PLLREGFGVAGLDPAAARVRVRSLVPDADPEDLLLLDDVLGIADPDVPMPDLDADARRRR 360 Query: 365 XXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGAL 424 +N A LA P ++V+ED HWIDEVS+SMLA+FL V+ T S+ L+TYRPEY G L Sbjct: 361 VAALVNAASLARREPGLYVLEDAHWIDEVSESMLAEFLTVVTHTHSVMLITYRPEYTGVL 420 Query: 425 RHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAE 484 V GAQ IA+ PL+D +TSTL+ ELLG D + Q+ LI +RAAGNPFF QEI R+LAE Sbjct: 421 ARVSGAQTIALRPLTDGQTSTLLTELLGPDAAAHQLAGLIADRAAGNPFFTQEIVRDLAE 480 Query: 485 RGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLL 544 RGVL GERG Y E+ VPATLQATIAARIDRL AK+ L AAAVIG RFG D+L Sbjct: 481 RGVLRGERGAYRFHGADVEIGVPATLQATIAARIDRLEVEAKRTLSAAAVIGLRFGPDML 540 Query: 545 ASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXX 604 A+LG D+S+ LIDA LVDQV F EYAFRHPLIR VA ESQLKSD Sbjct: 541 AALGADVSMQALIDAELVDQVMFAPRPEYAFRHPLIRMVALESQLKSDRAELHRRLAVDI 600 Query: 605 XXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADA 664 PH+ D+HA LIA+H E AGDL AA+ WHMRA W TN+D+ AAR+SW+ A +AD Sbjct: 601 ERRAPHAADEHAALIADHYEEAGDLRAAFTWHMRAGTWLTNRDIDAARLSWQRARHVADQ 660 Query: 665 LTAEDPHRAAMCIAPRTRLCGIAWR-GRFNSSSGFDEVRQLCNATGDKAPLAVATVG 720 L + RAAM IAPRT LC WR G S +GFDE+ L A DK LA A G Sbjct: 661 LPHDAEDRAAMTIAPRTLLCLSTWRAGGHLSDTGFDELCALAAAADDKVSLATAMAG 717 >tr|Q1BCN4|Q1BCN4_MYCSS Tax_Id=164756 SubName: Full=Adenylate/guanylate cyclase;[Mycobacterium sp.] Length = 1050 Score = 743 bits (1918), Expect = 0.0 Identities = 399/732 (54%), Positives = 495/732 (67%), Gaps = 5/732 (0%) Query: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 MT + C CG E A+FC CG+PV +A AEYKQVTVLFADVV SMDIAAAVG E Sbjct: 1 MTASTACRTCGTEYLDGARFCHGCGAPVGQAAAHAEYKQVTVLFADVVRSMDIAAAVGAE 60 Query: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 RLREIM +LV+R + V++R+GGTVDKFTGDGIMA+FGAP ALEDHA+RACLAALG+Q++A Sbjct: 61 RLREIMADLVNRCSAVVQRFGGTVDKFTGDGIMAVFGAPIALEDHAIRACLAALGIQQQA 120 Query: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 +LA V DG L+LR+GLNSGQVI G+I S ALGYTAVG VG AQRMESVA PG V Sbjct: 121 AQLATIVERHDGATLELRIGLNSGQVIAGDIASPALGYTAVGEHVGWAQRMESVAAPGGV 180 Query: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 ++S+STARLVE AVLG P+ V +KG + V RRL+ V P E LVGR WE+ Sbjct: 181 LVSDSTARLVEHVAVLGEPERVCVKGRDRPVSVRRLVGVRTPHAVAGPGEPHLVGRRWEM 240 Query: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 A + + +RSI G G+VV LVGP GIGK+R+ E A G VEVF FCESH +DV F Sbjct: 241 AAVEGIFERSIDGAGAVVALVGPPGIGKSRMAREIAMSAAGRGVEVFWSFCESHTSDVPF 300 Query: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXX 360 VV QL+R + + LD+ S R R+R + D Q I DPA Sbjct: 301 CVVGQLLRTIVGLPHLDEESVRTRLRTRF---DEQDVLLFEDLLEIRDPATALPAIDPDA 357 Query: 361 XXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 + A +A PA+++VED HWIDEVSD+MLADF+ VIPQT SM L+T+RP++ Sbjct: 358 RRRRLSRMVKAAAVARDSPALYIVEDAHWIDEVSDAMLADFVTVIPQTHSMVLLTHRPDF 417 Query: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 HGAL V GAQ + +APLSD E+ L LLG D SV + + +RAAGNPFFA+EI R Sbjct: 418 HGALSRVPGAQTLTLAPLSDSESVALARTLLGTDPSVADLVVTVAQRAAGNPFFAEEIVR 477 Query: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 +L ER +L G RG + C TDVA++ VPATLQATIAARIDRL P AKQ L AA+VIG RF Sbjct: 478 DLTERHLLHGRRGAFHCWTDVADISVPATLQATIAARIDRLPPSAKQTLCAASVIGMRFD 537 Query: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 + LL S+G+ +VD+L+ A L+D+V+FT E+AFRHPL+R VAYESQL+SD Sbjct: 538 TALLDSMGVTSTVDDLLHAELIDEVKFTGHAEFAFRHPLVRAVAYESQLRSDRVALHRRL 597 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 P SVD++A LIAEHLEAAGD AAY WHMR+AAW+ +D+RAA +SWE A+ Sbjct: 598 ADAIESAEP-SVDENAALIAEHLEAAGDPRAAYEWHMRSAAWSRQRDIRAALMSWERASM 656 Query: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFN-SSSGFDEVRQLCNATGDKAPLAVATV 719 +ADAL A + + IAPRT LC +R R + S F+E+R+LC A GDKA +A+A Sbjct: 657 LADALPAGGSDQFTLRIAPRTFLCANGFRNRNHVGSRRFEELRELCAAAGDKASVAIAMG 716 Query: 720 GPAIDHVYQDRL 731 G + + RL Sbjct: 717 GLINEQLIDGRL 728 >tr|A1UCA9|A1UCA9_MYCSK Tax_Id=189918 SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase;[Mycobacterium sp.] Length = 1050 Score = 743 bits (1918), Expect = 0.0 Identities = 399/732 (54%), Positives = 495/732 (67%), Gaps = 5/732 (0%) Query: 1 MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLE 60 MT + C CG E A+FC CG+PV +A AEYKQVTVLFADVV SMDIAAAVG E Sbjct: 1 MTASTACRTCGTEYLDGARFCHGCGAPVGQAAAHAEYKQVTVLFADVVRSMDIAAAVGAE 60 Query: 61 RLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKA 120 RLREIM +LV+R + V++R+GGTVDKFTGDGIMA+FGAP ALEDHA+RACLAALG+Q++A Sbjct: 61 RLREIMADLVNRCSAVVQRFGGTVDKFTGDGIMAVFGAPIALEDHAIRACLAALGIQQQA 120 Query: 121 RRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVV 180 +LA V DG L+LR+GLNSGQVI G+I S ALGYTAVG VG AQRMESVA PG V Sbjct: 121 AQLATIVERHDGATLELRIGLNSGQVIAGDIASPALGYTAVGEHVGWAQRMESVAAPGGV 180 Query: 181 MLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWEL 240 ++S+STARLVE AVLG P+ V +KG + V RRL+ V P E LVGR WE+ Sbjct: 181 LVSDSTARLVEHVAVLGEPERVCVKGRDRPVSVRRLVGVRTPHAVAGPGEPHLVGRRWEM 240 Query: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAF 300 A + + +RSI G G+VV LVGP GIGK+R+ E A G VEVF FCESH +DV F Sbjct: 241 AAVEGIFERSIDGAGAVVALVGPPGIGKSRMAREIAMSAAGRGVEVFWSFCESHTSDVPF 300 Query: 301 DVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXX 360 VV QL+R + + LD+ S R R+R + D Q I DPA Sbjct: 301 CVVGQLLRTIVGLPHLDEESVRTRLRTRF---DEQDVLLFEDLLEIRDPATALPAIDPDA 357 Query: 361 XXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY 420 + A +A PA+++VED HWIDEVSD+MLADF+ VIPQT SM L+T+RP++ Sbjct: 358 RRRRLSRMVKAAAVARDSPALYIVEDAHWIDEVSDAMLADFVTVIPQTHSMVLLTHRPDF 417 Query: 421 HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR 480 HGAL V GAQ + +APLSD E+ L LLG D SV + + +RAAGNPFFA+EI R Sbjct: 418 HGALSRVPGAQTLTLAPLSDSESVALARTLLGTDPSVADLVVTVAQRAAGNPFFAEEIVR 477 Query: 481 ELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 +L ER +L G RG + C TDVA++ VPATLQATIAARIDRL P AKQ L AA+VIG RF Sbjct: 478 DLTERHLLHGRRGAFHCWTDVADISVPATLQATIAARIDRLPPSAKQTLCAASVIGMRFD 537 Query: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 + LL S+G+ +VD+L+ A L+D+V+FT E+AFRHPL+R VAYESQL+SD Sbjct: 538 TALLDSMGVTSTVDDLLHAELIDEVKFTGHAEFAFRHPLVRAVAYESQLRSDRVALHRRL 597 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 P SVD++A LIAEHLEAAGD AAY WHMR+AAW+ +D+RAA +SWE A+ Sbjct: 598 ADAIESAEP-SVDENAALIAEHLEAAGDPRAAYEWHMRSAAWSRQRDIRAALMSWERASM 656 Query: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWRGRFN-SSSGFDEVRQLCNATGDKAPLAVATV 719 +ADAL A + + IAPRT LC +R R + S F+E+R+LC A GDKA +A+A Sbjct: 657 LADALPAGGSDQFTLRIAPRTFLCANGFRNRNHVGSRRFEELRELCAAAGDKASVAIAMG 716 Query: 720 GPAIDHVYQDRL 731 G + + RL Sbjct: 717 GLINEQLIDGRL 728 >tr|A3PVY7|A3PVY7_MYCSJ Tax_Id=164757 SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase;[Mycobacterium sp.] Length = 1055 Score = 695 bits (1793), Expect = 0.0 Identities = 389/731 (53%), Positives = 477/731 (65%), Gaps = 4/731 (0%) Query: 3 TALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERL 62 T C CG EL A+FC CGS +V +++ AEYK VTVLFADVV SM IAAAVG ERL Sbjct: 2 TVRACRTCGTELLDAARFCHGCGSELVNSDSHAEYKWVTVLFADVVRSMAIAAAVGPERL 61 Query: 63 REIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARR 122 REIM EL SR++ V+ RYGGTVDKFTGDGIMA+FGAP ALEDHA RACLAA +Q++++ Sbjct: 62 REIMAELFSRSSAVVRRYGGTVDKFTGDGIMAVFGAPLALEDHAFRACLAASAIQQESQV 121 Query: 123 LAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVML 182 L+ EV D D V LQLRVGLNSG VI GEIGS YT VG QVG+AQR+ESVAPPG V+L Sbjct: 122 LSREVEDHDRVTLQLRVGLNSGAVIAGEIGSQPRSYTTVGEQVGIAQRLESVAPPGGVLL 181 Query: 183 SESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELAT 242 SESTARL + T L P + +K A+ V ARRLL + E + E LVGR ELA Sbjct: 182 SESTARLAQDTVTLAPPVILTVKDADAPVVARRLLTI-EGHRVRDRGEPALVGRTRELAF 240 Query: 243 LAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDV 302 L A+LD +IGG GSVV +VGPAGIGK+RLV E +A V VF+ CESHA+D+ F Sbjct: 241 LTAILDETIGGSGSVVNVVGPAGIGKSRLVRELAAIAIRRNVAVFTSSCESHASDIPFYG 300 Query: 303 VAQLVRAVAQISGLD-DRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXXX 361 +++L+R I +D D +AR RVR++ + D GIADP+ Sbjct: 301 ISRLLRRGMGIDAVDGDDAARLRVRQRFTEGDDDDLLLLDDLLGIADPSAPLPDIAPEAR 360 Query: 362 XXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYH 421 IN + LA ++PAV++VEDVHWID VS+SML DFLAV+PQT S+ L+T+RPEY Sbjct: 361 RRRLTAMINASALAQTQPAVYIVEDVHWIDAVSESMLCDFLAVMPQTPSLVLITFRPEYR 420 Query: 422 GALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRE 481 GAL V GAQ IA+ PL++ + +TL LLG D S+T + ++ RAAGNPFF +EI R+ Sbjct: 421 GALTRVSGAQTIALRPLTEAQATTLATGLLGEDPSLTDLASKVSTRAAGNPFFIEEIVRD 480 Query: 482 LAERGVLTGERGRYACSTDVA-EVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 L ERGVL G G Y+ VA ++ VPATL ATI ARIDRLS AK L AAAVIG RF Sbjct: 481 LTERGVLEGAGGAYSLRGGVADDIDVPATLYATIGARIDRLSSTAKSTLNAAAVIGSRFD 540 Query: 541 SDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 ++LL + VD LI+A LVDQVRF P E+AFRHPLIR VAYESQL+S Sbjct: 541 AELLTRVVDGADVDPLIEAELVDQVRFGRPAEFAFRHPLIRAVAYESQLRSVRVQLHRRI 600 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK 660 P + D+HA LIAEH EAAGD AAY WHM+A W +D+ AR SW A + Sbjct: 601 AEVIESRDPAAADEHAALIAEHREAAGDFLAAYTWHMQAGDWLAKRDITGARNSWRRARQ 660 Query: 661 IADALTAEDPHRAAMCIAPRTRLCGIAWR-GRFNSSSGFDEVRQLCNATGDKAPLAVATV 719 +AD L R +M I PR LCG A+R G + +GFDE+R+LC A D LA+ Sbjct: 661 VADRLPDSVEDRLSMRITPRAFLCGTAFRVGGGGAETGFDELRELCVAARDTRSLAIGMN 720 Query: 720 GPAIDHVYQDR 730 G A H++ R Sbjct: 721 GLATVHLFDAR 731 >tr|A1T6C4|A1T6C4_MYCVP Tax_Id=350058 SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase;[Mycobacterium vanbaalenii] Length = 1014 Score = 512 bits (1319), Expect = e-143 Identities = 307/692 (44%), Positives = 402/692 (58%), Gaps = 9/692 (1%) Query: 40 VTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAP 99 +TVLFADVVGSM +AA + ERLREIM +L +R+A V++RY GT+DKFTGDG+MA+FGAP Sbjct: 1 MTVLFADVVGSMRLAAELDPERLREIMNDLFNRSATVVQRYHGTMDKFTGDGLMALFGAP 60 Query: 100 TALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYT 159 ALEDHALRAC+AAL +Q LA EV RDGV LQLRVGLNSG V+VG+IGS YT Sbjct: 61 MALEDHALRACIAALEIQAVVGELADEVEQRDGVRLQLRVGLNSGDVVVGDIGSGPGRYT 120 Query: 160 AVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRV 219 A+G VGMAQRME+ A G V+ S STA LVE LGA QTVRIKG+++ PARRL+ V Sbjct: 121 AIGHAVGMAQRMEAAASAGAVVCSLSTADLVEHATRLGAVQTVRIKGSDEPAPARRLVAV 180 Query: 220 AEPRQPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLA 279 R +E ++GR+ EL L LDR R +V +VG G+GK+RLV E + Sbjct: 181 EAARMVVGRNEGLMLGRDGELHQLCDSLDRR--RRRHLVSVVGAPGVGKSRLVEEFCRRL 238 Query: 280 KGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXX 339 +G EV C++HA +AF +++L+RA+ L D AR V Q+P T Sbjct: 239 RGAGTEVVLAGCDAHAMPIAFRALSRLLRAMFSADDLGDDDARELVLSQVPMGSTD-AQI 297 Query: 340 XXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLA 399 GIAD A + S P V V+ED HWID S+++L Sbjct: 298 IFEAMGIADGAAPPLHVGADGRRHRLVETMAQFVRLRSTPMVLVLEDAHWIDAASEAVLC 357 Query: 400 DFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQ 459 +F V+ +T ++ + T RPEY G LR A + VAPL+D T LV LLG D ++ Sbjct: 358 EFATVLERTSTVLVTTCRPEYRGGLRK-RSAHTVTVAPLNDSLTMDLVLNLLGGDGAMGG 416 Query: 460 IGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARID 519 + I AAGNP+F +EI R+L RGVL G RG Y DV ++ VP T+QA +AARID Sbjct: 417 LASRIVGVAAGNPYFVEEIVRDLVGRGVLAGSRGDYRLIRDVDDIGVPVTVQAVLAARID 476 Query: 520 RLSPPAKQLLVAAAVIGFRFGSDLLASLGIDL---SVDELIDANLVDQVRFTAPVEYAFR 576 RL+P K +L AAAVIG RF ++ L L + + EL+ L+DQ+ F Y FR Sbjct: 477 RLAPATKAVLNAAAVIGNRFDAETLQVLTPNARSGELAELVATELIDQMEFAPRQRYCFR 536 Query: 577 HPLIRTVAYESQLKSDXXXXXXXXXXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWH 636 HPL+R VAY+SQ+ ++ P + D++A LIA HLE AGD A WH Sbjct: 537 HPLVRAVAYDSQISANRARAHRLLAGAIETRDPAAKDENAALIATHLEGAGDFETACRWH 596 Query: 637 MRAAAWATNQDVRAARVSWEHATKIADALTAEDPHRAAMCIAPRTRLCG--IAWRGRFNS 694 +RAA W +D+ AAR WE A ++AD L D A+ IAPRT L + ++ Sbjct: 597 LRAADWLRMRDLLAARNQWEIAMRVADGLPGADDAVTALRIAPRTMLVSTELFVGADPDN 656 Query: 695 SSGFDEVRQLCNATGDKAPLAVATVGPAIDHV 726 E+R+L D LA+A G + + Sbjct: 657 DQRLVELRELTARVDDSHSLALALAGRIVTFI 688 >tr|Q1BCN6|Q1BCN6_MYCSS Tax_Id=164756 SubName: Full=Adenylate/guanylate cyclase;[Mycobacterium sp.] Length = 320 Score = 289 bits (740), Expect = 8e-76 Identities = 158/256 (61%), Positives = 184/256 (71%), Gaps = 1/256 (0%) Query: 3 TALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERL 62 T C CG EL A+FC CGS + +++ AEYK VTVLFADVV SM IAAAVG ERL Sbjct: 2 TVRACRTCGTELLDAARFCHGCGSELANSDSHAEYKWVTVLFADVVRSMAIAAAVGPERL 61 Query: 63 REIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARR 122 REIM EL SR++ V+ RYGGTVDKFTGDGIMA+FGAP ALEDHA RACLAA +Q++++ Sbjct: 62 REIMAELFSRSSAVVRRYGGTVDKFTGDGIMAVFGAPLALEDHAFRACLAASAIQQESQG 121 Query: 123 LAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVML 182 L+ EV DGV LQLRVGLNSG VI GEIGS YT VG QVG+AQR+ESVAPPG V+L Sbjct: 122 LSREVEAHDGVTLQLRVGLNSGAVIAGEIGSQPHSYTTVGEQVGIAQRLESVAPPGGVLL 181 Query: 183 SESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELAT 242 SESTARL + L P + +KGA+ V ARRLL + E + E LVGR ELA Sbjct: 182 SESTARLAQDMVTLAPPVILTVKGADAPVVARRLLTI-EGHRVRDRGEPALVGRTRELAF 240 Query: 243 LAAMLDRSIGGRGSVV 258 L A+LD +IGG GSVV Sbjct: 241 LTAILDETIGGSGSVV 256 >tr|A1UCA7|A1UCA7_MYCSK Tax_Id=189918 SubName: Full=Putative adenylate/guanylate cyclase;[Mycobacterium sp.] Length = 320 Score = 289 bits (740), Expect = 8e-76 Identities = 158/256 (61%), Positives = 184/256 (71%), Gaps = 1/256 (0%) Query: 3 TALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERL 62 T C CG EL A+FC CGS + +++ AEYK VTVLFADVV SM IAAAVG ERL Sbjct: 2 TVRACRTCGTELLDAARFCHGCGSELANSDSHAEYKWVTVLFADVVRSMAIAAAVGPERL 61 Query: 63 REIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARR 122 REIM EL SR++ V+ RYGGTVDKFTGDGIMA+FGAP ALEDHA RACLAA +Q++++ Sbjct: 62 REIMAELFSRSSAVVRRYGGTVDKFTGDGIMAVFGAPLALEDHAFRACLAASAIQQESQG 121 Query: 123 LAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVML 182 L+ EV DGV LQLRVGLNSG VI GEIGS YT VG QVG+AQR+ESVAPPG V+L Sbjct: 122 LSREVEAHDGVTLQLRVGLNSGAVIAGEIGSQPHSYTTVGEQVGIAQRLESVAPPGGVLL 181 Query: 183 SESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELAT 242 SESTARL + L P + +KGA+ V ARRLL + E + E LVGR ELA Sbjct: 182 SESTARLAQDMVTLAPPVILTVKGADAPVVARRLLTI-EGHRVRDRGEPALVGRTRELAF 240 Query: 243 LAAMLDRSIGGRGSVV 258 L A+LD +IGG GSVV Sbjct: 241 LTAILDETIGGSGSVV 256 >tr|Q46RQ2|Q46RQ2_RALEJ Tax_Id=264198 SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase:Tetratricopeptide TPR_4;[Ralstonia eutropha] Length = 1149 Score = 283 bits (725), Expect = 5e-74 Identities = 236/758 (31%), Positives = 338/758 (44%), Gaps = 86/758 (11%) Query: 7 CVACGAELRSIAKFCDECGSPV-------------------------------------- 28 C ACG E + AKFC ECGSP+ Sbjct: 28 CPACGQESAASAKFCSECGSPLNAPSSAPATSSGAVRATSTAPSTPIDYTPPYLAERILA 87 Query: 29 ------VEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGG 82 +T E K VT LFAD+ GS + + E R ++ +++ + Y G Sbjct: 88 AQAEMEARRQTDGERKMVTALFADMAGSTALIHDLDPEDARSLIDPVLALMMEAVHHYEG 147 Query: 83 TVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLN 142 V K GDGI+A+FGAP A EDH RA LAAL +QE R A V G+ LQ+RVG+N Sbjct: 148 YVAKSMGDGILALFGAPIANEDHPQRALLAALRMQEAMRHYADGVRLAQGIALQIRVGIN 207 Query: 143 SGQVIVGEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVE--------- 191 SG+V+V I L Y VG + +A RME++A PG ++ SE T L E Sbjct: 208 SGEVVVRTIRIKDLHTDYDPVGNSIHIASRMENIAVPGSIVASEHTRNLTEGYFAFKALG 267 Query: 192 QTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELATLAAMLDRSI 251 T+V G P+ + + P R L+V+ R F VGR EL L R+ Sbjct: 268 ATSVKGLPEPLEVFEVVGLGPLRTRLQVSASRGLARF-----VGRTRELEQLREARARAR 322 Query: 252 GGRGSVVGLVGPAGIGKTRLVAEAVQLAKG--LEVEVFSVFCESHATDVAFDVVAQLVRA 309 G G +VG+VG G+GK+RL E LA L +E FSV SH + + +L+R Sbjct: 323 AGHGQIVGVVGEPGVGKSRLCHEFKLLAPRDCLVLETFSV---SHGKAYPYLPLIELLRN 379 Query: 310 VAQISGLDD-RSARARVREQIPDADT---QXXXXXXXXXGIADPAVEXXXXXXXXXXXXX 365 QI+ DD R R ++ ++ D G+ +P Sbjct: 380 YCQITAQDDERRRREKLTGKLLTLDRALEDSLPYLCHLLGVVEPGSALAQMDNQIRQQRT 439 Query: 366 XXXIN--VAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY-HG 422 I + + +L++P V+ED+ W+D ++S L +P R + +V +RPEY H Sbjct: 440 FEAIKRLLVRESLTQPLELVIEDLQWLDSETESFLGFLGESVPSARILLVVNFRPEYRHD 499 Query: 423 ALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITREL 482 R Q+ + PL + E LV LLG + ++ +LI E+ GNPFF +E+ ++L Sbjct: 500 WSRKSYYTQL-RLDPLGEAEARDLVHALLGDATGLARLEQLILEQTEGNPFFIEEVVQDL 558 Query: 483 AERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSD 542 E VL GERG Y ++ +PAT+Q +AARIDRL P K LL AVIG F Sbjct: 559 VEGQVLRGERGHYRLVQIPGKLHIPATVQGVLAARIDRLQPAEKALLQTLAVIGKIFTWS 618 Query: 543 LLASLGIDLSVDE---LIDANLVDQVRFTAP----VEYAFRHPLIRTVAYESQLKSDXXX 595 LL S+ +DL D+ L+ + + P VEY+F+H L + V Y S L Sbjct: 619 LLGSV-VDLPEDKTKSLLARLQAGEFIYEQPAFPEVEYSFKHALTQEVTYGSLLSERRRA 677 Query: 596 XXXXXXXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSW 655 +++H +A H +G+ A + RA A + A V+ Sbjct: 678 LHERTAQAIETLFSAQLEEHCSELAYHFSRSGNTAKAVVYLHRAGRQAVQRSADAEAVT- 736 Query: 656 EHATKIADALTA--EDPHRAAMCIAPRTRLCGIAWRGR 691 H T L + P RA + + L G AW + Sbjct: 737 -HLTMALGLLATLPDCPERAQQELTLQITL-GPAWMAK 772 >tr|B8FAC8|B8FAC8_DESAA Tax_Id=439235 SubName: Full=Adenylate/guanylate cyclase;[Desulfatibacillum alkenivorans] Length = 1134 Score = 276 bits (705), Expect = 9e-72 Identities = 193/629 (30%), Positives = 295/629 (46%), Gaps = 46/629 (7%) Query: 6 VCVACGAELRSIAKFCDECGSPVVEAETPA----------------------------EY 37 VC CG+ LR AKFCD CGSP E PA E Sbjct: 27 VCPKCGSALRDGAKFCDRCGSPTRETSPPAPLDFNQPQSYTPKHLKDKILTTRSAIEGER 86 Query: 38 KQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFG 97 K VTVLFAD +++ + E + +IM I RY G++++FTGDG+MA+FG Sbjct: 87 KLVTVLFADAADFTEMSGMLDPEEVHQIMDGCFRILMDEIHRYEGSINQFTGDGVMALFG 146 Query: 98 APTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSS-AL 156 AP A EDHA RAC AAL +Q + ++ GV ++R+GLN+G V+V IG + Sbjct: 147 APVAHEDHAQRACHAALAIQRALKVYEEKIYKDLGVAFRMRIGLNTGPVVVSSIGDDLRM 206 Query: 157 GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRL 216 YTA+G +A RMES+A PG + +S +T RLV A V +KG ++ RL Sbjct: 207 DYTAIGDTANLASRMESLAEPGEIFISRNTYRLVNHFFECTALSPVAVKGKQEPQQVYRL 266 Query: 217 LRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLV 272 R + S + VGR LA L ++ G G LVG AG+GK+R++ Sbjct: 267 ERTGKAATRIEASAAKGLTRFVGRHNSLAALWEAWQKASSGSGQTASLVGEAGVGKSRIL 326 Query: 273 AEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRS--ARARVREQIP 330 E + + C + + + +++ + I DDR + ++R+++ Sbjct: 327 LEFRKRLAEQGIAYIEGCCLHYGASMPYLPFLDILKTLFAIEE-DDREFIVKKKIRDKVD 385 Query: 331 DADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQ--LALS---RPAVFVVE 385 + AV+ + L LS +P V VE Sbjct: 386 GLGENMAHLLLPLQALLSVAVDDPGWPGLEPQERRERTFEALRDLLILSSQDQPLVIAVE 445 Query: 386 DVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDVETST 445 D+HWID+ S+ L F+ I + ++ ++TYRPEY I V L+ ++ Sbjct: 446 DLHWIDKTSEEFLGYFMGWIAASPTLLVITYRPEYTHPWASRSYYSQIRVDQLTPKSSTE 505 Query: 446 LVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVC 505 L++ +L + V ++ +LI RAAGNP + +E+TR L E G + E ++A + Sbjct: 506 LISAMLEGGEVVPELRDLIITRAAGNPLYMEELTRSLLENGCIAKEGAQFALIGRAESLQ 565 Query: 506 VPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL-----GIDLSVDELIDAN 560 VP T+Q IAARIDRL K+ + A+VIG F +L ++ + S+ L Sbjct: 566 VPDTIQGIIAARIDRLEESLKRTMQVASVIGRDFAFKILQTVTGMRENLKKSLVNLQGLE 625 Query: 561 LVDQVRFTAPVEYAFRHPLIRTVAYESQL 589 + + + +EY F+H +I+ VAY+S L Sbjct: 626 FIYEKQLFPELEYIFKHVMIQEVAYDSLL 654 >tr|A4Z0R3|A4Z0R3_BRASO Tax_Id=114615 SubName: Full=Putative Adenylate cyclase; EC=4.6.1.1;[Bradyrhizobium sp.] Length = 1076 Score = 275 bits (703), Expect = 2e-71 Identities = 222/731 (30%), Positives = 332/731 (45%), Gaps = 67/731 (9%) Query: 5 LVCVACGAELRSIAKFCDECGSPVVEAETPA----------------EYKQVTVLFADVV 48 L C AC +FC +CG+P+ P+ E K++T+LFAD+ Sbjct: 26 LKCEACSHTNSPSNRFCGQCGAPLSGRLAPSDQSAQRVLRTLSSKGGERKRLTILFADIR 85 Query: 49 GSMDIAAAVGLERLR-EIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHAL 107 S + ++G L + + +++ + R+ G V+K GDG+MA+FGAP EDHA+ Sbjct: 86 DSTQLIDSLGDPELAMQRLDPVLNLMKEAVHRFDGVVNKTQGDGVMALFGAPVPHEDHAV 145 Query: 108 RACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALG-YTAVGVQVG 166 R CL AL +Q+ RL GD LQ+RVGL++G+VIV + +S Y A G V Sbjct: 146 RGCLGALAMQDSIGRL----GDPH---LQVRVGLHTGEVIVQVVENSMYQTYDAAGANVH 198 Query: 167 MAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLL-RVAEPRQP 225 +A R+E +A PG +++S+ T Q T ++G V +L+ R+ P Sbjct: 199 LANRLEHMAEPGTILVSKETYTGARQFVEAEPLGTHTVRGIASPVSIYKLIGRLNAPASD 258 Query: 226 TWFSESTL---VGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGL 282 + S L +GR+ + L LD + RG+VVG+VG AGIGK+RL E + + Sbjct: 259 VFRSGQRLLPLIGRKAQFDVLERELDNVLAARGAVVGIVGEAGIGKSRLCFEFAEHCRRQ 318 Query: 283 EVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDD-RSARARVREQI-----PDADTQX 336 + V+ +H F V +L+R I + +R RV E++ PD Sbjct: 319 GIRVYEARVLAHGRTTPFQPVLELLRDFFGIRPKEPVEVSRQRVVEKLEAIGLPDT---A 375 Query: 337 XXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQ-LALSRPA----VFVVEDVHWID 391 G+ADPA +NV + L + PA V ++ED+HWID Sbjct: 376 LVLLLDFMGLADPA---RPALRLDPGVFKSRLLNVFRTLFRAAPADGGSVIMIEDLHWID 432 Query: 392 EVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDVETSTLVAELL 451 E S+ + T+++ +V YRP + + + + PL+ E L+ + Sbjct: 433 EASEEFVEALAEATIGTKTLLVVNYRPGFAASFMQRAAFHELHIVPLASAEARELLRGVF 492 Query: 452 GLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQ 511 G D S+ + I ERA GNPFF +E+ ++E GERG Y + + +P T+ Sbjct: 493 GDDPSLQALAGDIVERAQGNPFFLEELASAVSESSDFEGERGAYRLKGGIGPIPLPPTVH 552 Query: 512 ATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDLSVDELIDANLVD---QVRFT 568 A +AARIDRL AK +L AAVIG +L + V L+DA L D Q+R Sbjct: 553 AVVAARIDRLGETAKNVLETAAVIG------RSVALSVLKPVTGLVDAELFDALAQLR-N 605 Query: 569 APVEY----------AFRHPLIRTVAYESQLKSDXXXXXXXXXXXXXXXXPHSVDQHAVL 618 A + Y AFRHPLI+ VAY QL+S S D+ A L Sbjct: 606 ADLLYDLPPFDMGVLAFRHPLIQEVAYAMQLRSRLSTVHAAVAKAIEALDWGSQDEFAAL 665 Query: 619 IAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALTAEDPHRAAMCIA 678 IA H E AG + RAA W + A W+ + A+ E H + Sbjct: 666 IASHYEFAGQTIQSVEHLQRAARWIGRTNTAEALRLWKKIRAMLQAM-PESEHVERLRSL 724 Query: 679 PRTRLCGIAWR 689 ++ WR Sbjct: 725 ASAQILNFGWR 735 >tr|Q0K118|Q0K118_RALEH Tax_Id=381666 SubName: Full=ATP synthase beta subunit/transription termination factor rho;[Ralstonia eutropha] Length = 1155 Score = 273 bits (699), Expect = 5e-71 Identities = 210/647 (32%), Positives = 308/647 (47%), Gaps = 72/647 (11%) Query: 7 CVACGAELRSIAKFCDECG-----SPVVEAETPA-------------------------- 35 C CG E + AKFC CG +PV A TPA Sbjct: 28 CPQCGEEATAAAKFCRACGFALTDAPVGTAATPAPPAATAPVLYTPPHLAGRILAEQAAM 87 Query: 36 --------EYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKF 87 E K +T LFAD+ GS + + E R ++ +V+ + Y G V KF Sbjct: 88 EARGETAGERKTITALFADMAGSTALTQDLDPEDARRLIDPVVTLMMEAVHHYEGYVAKF 147 Query: 88 TGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVI 147 GDGI+A+FGAP A EDHALRA AAL +Q+ R + V G+ LQ+R+G+++G+V+ Sbjct: 148 LGDGILALFGAPIAHEDHALRALYAALRMQDAMHRHSDRVRLEQGIPLQIRIGVHTGEVV 207 Query: 148 VGEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIK 205 V I L Y VG + +A RME +A P +++SEST +L E A T +K Sbjct: 208 VRSIRKDDLHTDYDPVGHTIHIASRMEGIATPASILVSESTHKLTEGYFEFTALGTTHVK 267 Query: 206 GAEDAVPA---------RRLLRVAEPRQPTWFSESTLVGREWELATLAAMLDRSIGGRGS 256 G D + R L+VA R F VGR+ ELA L A L ++ G G Sbjct: 268 GVRDPLAVYEVVGLGALRTRLQVAAHRGLARF-----VGRQDELAHLHAALGQAKAGHGR 322 Query: 257 VVGLVGPAGIGKTRLVAE-AVQLAKG-LEVEVFSVFCESHATDVAFDVVAQLVRAVAQIS 314 +V +VG AG+GK+RL E V+ +G L +E FSV SH A+ + +++++ QI+ Sbjct: 323 IVAVVGEAGVGKSRLFHEFKVRSQQGCLALETFSV---SHGKAFAYLPLIEMLKSYFQIT 379 Query: 315 GLD-DRSARARVREQIPDAD---TQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXIN 370 D DRS R +V ++ D + G +P I Sbjct: 380 AQDGDRSCREKVTGRLLTLDRSLEEHLPYLLYLLGTIEPDSPLPTMDPTIRRQRTFEAIA 439 Query: 371 --VAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVV 428 + + +L++P + ED+ W+D +++ L + +P R + LV YRPEY Sbjct: 440 RLLVRESLNQPLEVIFEDLQWLDGETEAFLNMLIDHVPGARILLLVNYRPEYSHRWNADG 499 Query: 429 GAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVL 488 + + PL E L+ LLG D+S+ + LI ++ GNPFF +E+ + LAE G L Sbjct: 500 HYSQLQLQPLGQAEAQELLTALLGDDRSLVPLKRLILDKTEGNPFFMEEVVQTLAEEGAL 559 Query: 489 TGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL- 547 G+ G Y T A + +P T+Q +AARIDRL K+LL AVIG F L+ + Sbjct: 560 LGQPGCYRIETAPALLHIPTTVQGVLAARIDRLPLAQKELLQTLAVIGKEFPLSLVLRVT 619 Query: 548 -----GIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQL 589 + + +L A+ + + VEYAF+H L + VA S L Sbjct: 620 GLPEDHLHPLLSDLQAADFIYERPAFPEVEYAFKHALTQEVAGSSLL 666 >tr|B3RAH8|B3RAH8_CUPTR Tax_Id=164546 SubName: Full=Putative adenylate cyclase; with Tetratricopeptide TPR_4 motifs for protein-protein interaction; EC=4.6.1.1;[Cupriavidus taiwanensis] Length = 1156 Score = 272 bits (696), Expect = 1e-70 Identities = 212/658 (32%), Positives = 310/658 (47%), Gaps = 86/658 (13%) Query: 4 ALVCVACGAELRSIAKFCDECGSPVVEA-------------------------------- 31 A VC CGAE + A+FC CG + +A Sbjct: 25 ARVCPQCGAEATAAARFCRVCGVGLPDAPAAAAPAPAAPRQDSPAPVHYTPPHLAGRILA 84 Query: 32 ---------ETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGG 82 ET E K +T LFAD+ GS + + E R ++ +V+ + Y G Sbjct: 85 EQAAMEARGETAGERKTITALFADMAGSTALTQDLDPEDARRLIDPVVTLMMEAVHHYEG 144 Query: 83 TVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLN 142 V KF GDGI+A+FGAP A EDHALRA AAL +Q+ R + V G+ LQ+R+G++ Sbjct: 145 YVAKFLGDGILALFGAPIAHEDHALRALYAALRMQDAMHRHSDRVRLEQGIPLQVRIGIH 204 Query: 143 SGQVIVGEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQ 200 +G+V+V I L Y VG + +A RME +A P +++SEST +L E A Sbjct: 205 TGEVVVRSIRKDDLHTDYDPVGHTIHIASRMEGIATPASILVSESTHKLTEGYFEFTALG 264 Query: 201 TVRIKGAEDAV---------PARRLLRVAEPRQPTWFSESTLVGREWELATLAAMLDRSI 251 T +KG + + P R L+VA R F VGR+ ELA L A L+++ Sbjct: 265 TTNVKGVREPLAVYEVIGPGPLRTRLQVAAHRGLARF-----VGRQDELAHLNAALEQAK 319 Query: 252 GGRGSVVGLVGPAGIGKTRLVAE-AVQLAKG-LEVEVFSVFCESHATDVAFDVVAQLVRA 309 GRG +V +VG AG+GK+RL E V+ +G L +E FSV SH A+ + ++++ Sbjct: 320 AGRGRIVAVVGEAGVGKSRLFHEFKVRSQQGCLALETFSV---SHGKAFAYLPLIEMLKN 376 Query: 310 VAQISGLD-DRSARARVREQIPDAD---TQXXXXXXXXXGIADPAVEXXXXXXXXXXXXX 365 QI+ D DRS R ++ ++ D + G+ +P Sbjct: 377 YFQITAHDGDRSCREKLTGRLLTLDRSLEEHLPYLLYLLGVVEPDSPLPTMDPALRRQRT 436 Query: 366 XXXIN--VAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGA 423 I + + + ++P + ED+ W+D +++ L + +P R + LV YRPEY Sbjct: 437 FDAIARLLVRESQNQPLEVIFEDLQWLDGETEAFLNMLVDHVPGARIVLLVNYRPEYSHR 496 Query: 424 LRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELA 483 + + PL E L+ LLG D S+ + LI ++ GNPFF +E+ + LA Sbjct: 497 WEAGAHYSQLRLQPLGQAEAQELLTALLGDDPSLAPLKRLILDKTEGNPFFMEEVVQTLA 556 Query: 484 ERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDL 543 E G L G+ G Y A + +P T+Q +AARIDRL K+LL AVIG F Sbjct: 557 EEGALLGQPGSYRIEKAPALLHIPTTVQGVLAARIDRLPLAQKELLQTLAVIGKEF---- 612 Query: 544 LASLGIDLSVDELIDANLVDQVR--------FTAP----VEYAFRHPLIRTVAYESQL 589 LG+ L V L + L +R + P VEYAF+H L + VA S L Sbjct: 613 --PLGLVLRVTGLPEERLHPLLRDLQSADFIYERPAFPEVEYAFKHALTQEVAGSSLL 668 >tr|Q0JZ82|Q0JZ82_RALEH Tax_Id=381666 SubName: Full=Two domain protein: Adenylate cyclase, family protein; EC=3.6.-.-;[Ralstonia eutropha] Length = 1137 Score = 268 bits (686), Expect = 1e-69 Identities = 211/713 (29%), Positives = 324/713 (45%), Gaps = 29/713 (4%) Query: 33 TPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGI 92 T E K +T LFAD+ GS + + E R ++ +++ + Y G V K GDGI Sbjct: 93 TAGERKTITALFADMAGSTALIHDLDPEEARRLIDPVIALMMEAVHHYEGYVAKSLGDGI 152 Query: 93 MAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIG 152 +A+FGAP A EDH RA AAL +QE RR + G+ LQ+RVG+++G+V+V I Sbjct: 153 LALFGAPIAHEDHPQRALYAALRMQEAMRRHGDRIRLEQGIPLQIRVGIHTGEVVVRSIR 212 Query: 153 SSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDA 210 L Y VG + +A RMES+A P +++SE+T RL E A ++KG + Sbjct: 213 RDDLHTDYDPVGHTINIASRMESIATPSSILVSEATCRLTEGYFDFKALGATQVKGIREP 272 Query: 211 VPARRLLRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGI 266 + +LR+ R ++ + VGRE ELA L L+R+ G G +VG+VG AG+ Sbjct: 273 LAVYEVLRLGVLRTRLQVAQRRGLAQFVGREGELAQLRDALERAKAGHGQIVGVVGEAGV 332 Query: 267 GKTRLVAEAVQLAKG--LEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDD-RSARA 323 GK+RL E L++ + +E FSV SH A+ + LV+ QI LDD R R Sbjct: 333 GKSRLFHEFKVLSQRGCMVLETFSV---SHGKSFAYLPLIDLVKNYFQIEPLDDERRCRE 389 Query: 324 RVREQIPDAD---TQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXIN--VAQLALSR 378 +V ++ D + GI++P I + + + ++ Sbjct: 390 KVAGRMLMLDRTLEELLPYLLFLLGISEPGSALPNMDPRIRRQRTFDAITRLLVRESHNQ 449 Query: 379 PAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPL 438 P + ED+ W+D +++ L + +P R + L+ YRPEY + + PL Sbjct: 450 PLELIFEDLQWLDSETEAFLDVLASHLPGARILLLLNYRPEYQHGRHQPDRYTELRLDPL 509 Query: 439 SDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACS 498 E L+A LLG D ++ + LI ++ GNPFF +E+ + L+E L GE G Y Sbjct: 510 GQAEAQELLAALLGDDPALMPLKRLILDKTEGNPFFMEEVVQTLSEEKALLGEPGHYRIE 569 Query: 499 TDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDLSVDEL-- 556 + +P T+Q +AARIDRL P K LL + AVIG F L+ + + ++L Sbjct: 570 QTPIALHIPTTVQGVLAARIDRLPRPEKDLLQSLAVIGKEFSLSLIQRV-VSQPEEQLQP 628 Query: 557 ----IDANLVDQVRFTAP-VEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXXXXXPHS 611 ++A R P EY F+H L + VA S L + H Sbjct: 629 LLARLEAGEFIYERPAFPDTEYMFKHALTQEVAGSSLLTEERTALHQRTAQAIEALFQHQ 688 Query: 612 VDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALTAEDPH 671 + H +A H +G+ A + A + + +A + P Sbjct: 689 LKDHYSELARHYSLSGNEPKAVEYLQCTGQQAVQRSAYHEAIRHLNAALELLQRQPDSPE 748 Query: 672 RAAMCIAPRTRL--CGIAWRGRFNS--SSGFDEVRQLCNATGDKAPLAVATVG 720 RA + R + IA RG +S + + LC G+ L VG Sbjct: 749 RARQELTLRLAIGPALIAARGFASSEVETTYSRALALCGEVGETPQLFPTLVG 801 >tr|Q46V35|Q46V35_RALEJ Tax_Id=264198 SubName: Full=Adenylate/guanylate cyclase;[Ralstonia eutropha] Length = 1138 Score = 264 bits (674), Expect = 4e-68 Identities = 206/675 (30%), Positives = 306/675 (45%), Gaps = 50/675 (7%) Query: 3 TALVCVACGAELRSIA-----------------------KFCDECGSPVVEAETPAEYKQ 39 TA C CGA L +A + E + E E K Sbjct: 38 TAKFCRGCGAALAGLAASQPSASAQVAAPVQYTPPHLAERILAERAAMEARGEAAGERKT 97 Query: 40 VTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAP 99 +T LFAD+ GS + + E R ++ + + + Y G V KF GDGI+A+FGAP Sbjct: 98 ITALFADMAGSTALTQDLDPEEARRLIDPVATLMMEAVHHYEGYVAKFLGDGILALFGAP 157 Query: 100 TALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSAL--G 157 A EDHALRA AAL +QE RR + V G+ LQ+RVG+++G+V+V I L Sbjct: 158 IAHEDHALRALYAALRMQEAMRRHSDRVRLELGIPLQIRVGIHTGEVVVRSIRKDDLHTD 217 Query: 158 YTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLL 217 Y VG + +A RME VA P +++SEST +L E A T +KG + +P +L Sbjct: 218 YDPVGHTIHIASRMEGVATPASILISESTHKLTEGYFEFKALGTTHVKGVREPLPVYEVL 277 Query: 218 RVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVA 273 + R + + VGR+ EL L A LD + G G +VG+VG AG+GK+RL Sbjct: 278 GLGPLRTRLQVAAHRGLARFVGRQAELEQLHAALDLAKAGSGQIVGVVGEAGVGKSRLFH 337 Query: 274 EAVQLAKG--LEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLD-DRSARARVREQIP 330 E ++ L +E FSV SH A+ + +L++ Q++ D DR R +V ++ Sbjct: 338 EFKARSRQGCLVLETFSV---SHGKAFAYLPLIELLKNYFQVAAQDNDRVCREKVTGRLL 394 Query: 331 DADTQ---XXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQLAL----SRPAVFV 383 D G +DP + +AQL + ++P + Sbjct: 395 TLDRSLEPHLPYLLYLLGSSDP--DSTLPTMDATIRRQRTFEAIAQLLVRESQNQPLALI 452 Query: 384 VEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDVET 443 ED+ W+D ++ L + +P + V YRPEY + + PL E Sbjct: 453 FEDLQWLDSETEGFLNILVDHVPAASILLQVNYRPEYAHEWHGRGAYTQLHLEPLGPAEA 512 Query: 444 STLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAE 503 L+ LLG D+S+ + LI ++ GNPFF +E+ + L E GVL G G + A Sbjct: 513 QGLLTALLGDDRSLVPLKRLILDKTEGNPFFMEEVVQTLTEEGVLLGVSGSFRIEQAPAL 572 Query: 504 VCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL--GIDLSVDELIDANL 561 + +P T+Q +AARIDRL K+LL AVIG F L+ + D ++ L+ A Sbjct: 573 LHIPTTVQGVLAARIDRLPVAQKELLQTLAVIGKEFSLSLIRHVTGADDNALRPLLTALQ 632 Query: 562 VDQVRFTAP----VEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXXXXXPHSVDQHAV 617 + P VEYAF+H L + VA S L P + + Sbjct: 633 AADFIYEQPAFPDVEYAFKHGLTQEVAGHSLLTERRSALHERTAHAIESLFPGRLKDYCG 692 Query: 618 LIAEHLEAAGDLHAA 632 +A H +G++ A Sbjct: 693 ELAHHYSLSGNVPKA 707 >tr|B5WAJ2|B5WAJ2_9BURK Tax_Id=516466 SubName: Full=Adenylate/guanylate cyclase;[Burkholderia sp. H160] Length = 1061 Score = 261 bits (668), Expect = 2e-67 Identities = 215/723 (29%), Positives = 332/723 (45%), Gaps = 35/723 (4%) Query: 32 ETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDG 91 ET E K VT LFAD+ GS + + E +++ +V+ + Y G V K GDG Sbjct: 6 ETAGERKTVTALFADMAGSTALIHGLDPEEAHQLIDPVVALMMEAVHYYEGYVAKSLGDG 65 Query: 92 IMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEI 151 I+A+FGAP A EDH RA AAL +Q+ R + G+ LQ+RVG+++G+V+V I Sbjct: 66 ILALFGAPIAHEDHPQRALFAALRMQQAMRGHGDRIRLEKGIPLQVRVGVHTGEVVVRSI 125 Query: 152 GSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAED 209 + L Y VG + +A RME +A P +++SEST +L E A ++KG + Sbjct: 126 RTDDLHTDYDPVGHTIHIASRMEGIATPTSILVSESTHKLAEGYFEFKALGAAQVKGIPE 185 Query: 210 AVPARRLLRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAG 265 +P LL R + + VGR+ E+A L L+ + GRG VVG+VG AG Sbjct: 186 PLPVYELLGPGALRTRLQLAAHRGLARFVGRQTEMAHLNQALEAARAGRGQVVGVVGEAG 245 Query: 266 IGKTRLVAEAVQLAKG--LEVEVFSVFCESHATDVAFDVVAQLVRAVAQI-SGLDDRSAR 322 +GK+RL E + ++ L +E FSV SH A + +L+++ QI +G D+R R Sbjct: 246 VGKSRLFHEFKERSRRGCLVLETFSV---SHGKAFANLPLIELMKSYFQITAGDDERRCR 302 Query: 323 ARV-----REQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQLALS 377 +V + D G + A+ +A+ + + Sbjct: 303 EKVIGKALTLERSFEDLVPYLLYLLGTGESASALAEMDPKVRRDRTFDAITQLLARESRN 362 Query: 378 RPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAP 437 +P + ED+ W+D +++ L + +P TR + LV YRPEY + + + Sbjct: 363 QPIELLFEDLQWLDRETEAFLTYLVERVPGTRILLLVNYRPEYQPGWDY----DQLRLEA 418 Query: 438 LSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYAC 497 L VE L+ LLG D S+ + +LI E+ GNPFF +E+ + LAE L GE GRY Sbjct: 419 LGPVEAQGLLTALLGDDASLLPLRQLILEKTEGNPFFMEEVVQTLAEERSLLGEPGRYRV 478 Query: 498 STDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL------GIDL 551 A + +P T+Q +AARIDRL+ K+LL AVIG F L+ + D Sbjct: 479 ERTPAALHIPTTVQGVLAARIDRLALAEKELLQTLAVIGKEFPFSLIQRICGGQLARTDD 538 Query: 552 SVDELIDANLVDQVRFTAP----VEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXXXX 607 + EL+ + + P VEY+F+H L + VA S L Sbjct: 539 DLRELLAHLEASEFIYERPAFPEVEYSFKHALTQEVAGHSLLTERRSALHERTAKAIEAL 598 Query: 608 XPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALTA 667 P + + +A H +G++ A + RAA A A + A Sbjct: 599 FPTRIADYCSELAHHYSLSGNIPKAVEYLHRAAQQALRHAAHADAMHHLGAALGLLERLP 658 Query: 668 EDPHRAA----MCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGPAI 723 + P RA+ + ++ L + G + + RQL G+ + L A +G I Sbjct: 659 DTPARASRELMLLLSLGPALMDVRGYGAPEVGATYTRARQLSEQFGETSQLFAALLGLRI 718 Query: 724 DHV 726 +V Sbjct: 719 YNV 721 >tr|Q39P44|Q39P44_BURS3 Tax_Id=269483 SubName: Full=Adenylate/guanylate cyclase;[Burkholderia sp.] Length = 1148 Score = 258 bits (660), Expect = 2e-66 Identities = 216/795 (27%), Positives = 339/795 (42%), Gaps = 87/795 (10%) Query: 7 CVACGAELRSIAKFCDECGSPVV------------------------------------- 29 C CG ++ +A+FC CG+P+ Sbjct: 28 CPHCGHDVAPVARFCSNCGTPLAAPTAASPPSRPSGREPPPTPVHYTPDHLAERIRAEHA 87 Query: 30 ----EAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVD 85 E E K VT LFAD+ GS + + E ++ +V + Y G V Sbjct: 88 AMAARGEPAGERKTVTALFADMAGSTALIHDLDPEVAHRLIVPVVELMMEAVHYYEGYVA 147 Query: 86 KFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQ 145 K GDGI+A+FGAP A EDHA RA AAL +Q+ R+ + ++G+ LQ+RVG+++G+ Sbjct: 148 KSLGDGILALFGAPIAHEDHAQRALFAALRMQQAMRQHGDRIRLQEGIPLQIRVGVHTGE 207 Query: 146 VIVGEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVE---------QTA 194 V+V I + L Y +G + +A R+E +A P +++SEST +L E T Sbjct: 208 VVVRSIRTDDLHTEYDPLGHTIHIASRIEGIAAPTSILVSESTHKLAEGYFEFKALGATQ 267 Query: 195 VLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELATLAAMLDRSIGGR 254 + G P +R+ R L++A R F VGRE E+ L + G+ Sbjct: 268 LKGIPAPLRVYEVLGLGALRTRLQLAAHRGLARF-----VGRETEMEHLNRARETVSAGQ 322 Query: 255 GSVVGLVGPAGIGKTRLVAEAVQLAK--GLEVEVFSVFCESHATDVAFDVVAQLVRAVAQ 312 G VVG+ G AG+GK+RL E + ++ L +E FSV SH + + +L++ Q Sbjct: 323 GRVVGVAGDAGVGKSRLFHEFKERSRRGALVLETFSV---SHGKAYSNLPLIELLKNYFQ 379 Query: 313 ISGLDDRSARARVREQI---------PDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXX 363 I+ DD R RE++ D G P + Sbjct: 380 ITTQDD---ERRCREKVIGKALTLERSFEDLVPYVLYLLGIGEGGPVLVEMDPQIRRERT 436 Query: 364 XXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGA 423 +A+ + ++P + ED+ W+D +++ L + +P R + LV YRPEY A Sbjct: 437 FDAIRQLLARESRNQPVHLLFEDLQWLDRETEAFLTYLIDHVPDARILLLVNYRPEYQPA 496 Query: 424 LRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELA 483 + + PL + L+A LLG D+++ + +LI E+ GNPFF +E+ + L Sbjct: 497 WVRAAHGSTLRLEPLGPADAQGLLAALLGEDRTLVPLKQLILEKTEGNPFFMEEVVQTLV 556 Query: 484 ERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDL 543 E L GE GRY A + +P T+Q +AARIDRL K+LL A AVIG F L Sbjct: 557 EERSLLGEAGRYRIVETPATLHIPTTVQGVLAARIDRLPIDEKELLQALAVIGHEFPFSL 616 Query: 544 LASL-GIDLSVDE--------LIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXX 594 + + G + + D+ L A + + V Y+F+H L + VA S L Sbjct: 617 IRRICGEETARDDELRRLLAHLEAAEFIYECPAFPEVNYSFKHALTQEVAGRSLLTERRT 676 Query: 595 XXXXXXXXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVS 654 P + + +A H +G++ A + RAA A ++ Sbjct: 677 TLHERTAHAIEVLFPTRIADYCSELAHHYSQSGNVPKAVEYLHRAAQQALRHAAHHDAMN 736 Query: 655 WEHATKIADALTAEDPHRA----AMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGD 710 A + P RA A+ ++ L + G + +LC TG+ Sbjct: 737 HLGAALALLKGLPDTPMRAHSELALLLSLGPVLMDVRGYGANEVGEAYRRALELCERTGE 796 Query: 711 KAPLAVATVGPAIDH 725 + +G I H Sbjct: 797 ASQRFATQLGLRIHH 811 >tr|Q46MZ4|Q46MZ4_RALEJ Tax_Id=264198 SubName: Full=Adenylate/guanylate cyclase;[Ralstonia eutropha] Length = 1139 Score = 258 bits (658), Expect = 3e-66 Identities = 214/729 (29%), Positives = 319/729 (43%), Gaps = 68/729 (9%) Query: 4 ALVCVACGAELRSIAKFCDECG---------------SPVV----------EAETPA--- 35 A +C CG + AKFC CG +PVV AE A Sbjct: 25 AQICPQCGHASSADAKFCGACGVLLANPASAPAPPLPAPVVYTPPHLAERIRAERAAMEA 84 Query: 36 -------EYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFT 88 E K +T LFAD+ GS + + E R ++ +V+ + Y G V K Sbjct: 85 KGTDADGERKTITALFADMAGSTALIQDLDPEEARSLIDPVVALMMEAVHHYEGYVAKSL 144 Query: 89 GDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIV 148 GDGI+A+FGAP A EDHALRA AAL +Q+ R + +V G+ LQ+RVG+++G+V+V Sbjct: 145 GDGILALFGAPIAHEDHALRALFAALRMQQAMRAHSDKVRLEQGIPLQIRVGVHTGEVVV 204 Query: 149 GEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKG 206 I L Y VG + +A RME VA P +++SEST RL E A +IKG Sbjct: 205 RSIRKDDLRTDYDPVGHTMHIAARMEGVATPSSILVSESTYRLAEGYFEFKALGRTQIKG 264 Query: 207 AEDAVPARRLLRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVGLVG 262 + + +L + R + VGR EL L L + GRG +VG+ G Sbjct: 265 LREPLVVYEVLGLGALRTRLQVGAHRGLARFVGRGAELERLGQALALANTGRGQIVGVGG 324 Query: 263 PAGIGKTRLVAEAVQLAKG--LEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRS 320 AG+GK+RL E A+ + +E FSV SH + + L+R QI+ DD Sbjct: 325 EAGVGKSRLFHEFKARAQQGCMVLETFSV---SHGKAFPYLPLIDLLRNYFQITAQDD-- 379 Query: 321 ARARVREQ-------IPDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXIN--V 371 R RE+ + A G ++P I + Sbjct: 380 -ERRYREKATGRLLILDRALEDHLPYLLYLLGFSEPGSALLTMDPTIRRQRTFDAITRLL 438 Query: 372 AQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQ 431 + + ++ + + ED+ W+D +++ L + +P R + LV YRPEY + Sbjct: 439 VRESQNQTLMVLFEDLQWLDSETEAFLNVLMEAVPSARILLLVNYRPEYRHDWCRIPCYT 498 Query: 432 IIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGE 491 + + PL E L++ LLG D S+ + +L+ + GNPFF +E+ + LAE L G+ Sbjct: 499 QLQLEPLGQAEAEGLLSALLGDDASLVPLKQLVLSKTEGNPFFMEEVVQTLAEEHTLLGQ 558 Query: 492 RGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDL 551 G Y + +P T+Q +AARIDRL P K+LL AVIG F + L+ + Sbjct: 559 PGNYRIDKPPLTLHMPTTVQGVLAARIDRLPIPQKELLQTLAVIGTDFPASLVRH--VTG 616 Query: 552 SVDELIDANLVD----QVRFTAP----VEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXX 603 D+ + LVD + P VEYAF+H L + VA S L Sbjct: 617 QPDDTLQPLLVDLRAGDFIYERPSFPEVEYAFKHALTQEVAGNSLLSGQRSRLHERTARA 676 Query: 604 XXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIAD 663 P + ++ +A H +G++ A + RA A + + + A Sbjct: 677 IETLFPDRLTEYCSELAHHYSQSGNVPKAVEYLQRAGEQAMQRSAQLEAIGHLRAALELV 736 Query: 664 ALTAEDPHR 672 E P R Sbjct: 737 KTLPESPER 745 >tr|B1Z5L4|B1Z5L4_BURA4 Tax_Id=398577 SubName: Full=Adenylate/guanylate cyclase with TPR repeats;[Burkholderia ambifaria] Length = 1151 Score = 252 bits (643), Expect = 1e-64 Identities = 216/788 (27%), Positives = 339/788 (43%), Gaps = 71/788 (9%) Query: 7 CVACGAELRSIAKFCDECGSPV-------------------------------------- 28 C CG + A+FC CG+ + Sbjct: 28 CPRCGHDADPAARFCSNCGASLETTAAAPPPSRPSAPELPPTPVHYTPDHLAERIRAEHA 87 Query: 29 ---VEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVD 85 E E K VT LFAD+ GS + + E ++ +V + Y G V Sbjct: 88 AMEARGEPAGERKTVTALFADMAGSTALIHDLDPEVAHRLIVPVVELMMEAVHYYEGYVA 147 Query: 86 KFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQ 145 K GDGI+A+FGAP A EDHA RA AAL +Q+ R+ + ++G+ LQ+RVG+++G+ Sbjct: 148 KSLGDGILALFGAPIAHEDHAQRALFAALRMQQAMRQHGDRIRLQEGIPLQIRVGVHTGE 207 Query: 146 VIVGEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVR 203 V+V I + L Y +G + +A R+E +A P +++SEST +L E A + Sbjct: 208 VVVRSIRTDDLHTEYDPLGHTIHIASRIEGIAAPTSILVSESTHKLAEGYFEFKALGATQ 267 Query: 204 IKGAEDAVPARRLLRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVG 259 +KG + +L + R + + VGRE E+ L LD G G VVG Sbjct: 268 LKGIPAPLCVYEVLGLGALRTRLQLAAHRGLARFVGRETEMEHLNRALDTMRAGHGRVVG 327 Query: 260 LVGPAGIGKTRLVAEAVQLAK--GLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLD 317 +VG AG+GK+RL E + ++ L +E FSV SH + +L++ QI+ D Sbjct: 328 VVGEAGVGKSRLFHEFKERSRRGALVLETFSV---SHGKAFPNLPLIELLKNYFQITTQD 384 Query: 318 D-RSARARVREQ---IPDADTQXXXXXXXXXGIAD--PAVEXXXXXXXXXXXXXXXXINV 371 D R R +V + + + + GI + P + + Sbjct: 385 DERRCREKVIGKALTLERSFEELVPYVLYLLGIGEGSPVLAEMDPQIRRERTFDAIRQLL 444 Query: 372 AQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQ 431 + + ++P + ED+ W+D +++ L + +P R + LV YRPEY A Sbjct: 445 VRESRNQPLHLLFEDLQWLDRETEAFLTYLIDHVPDARILLLVNYRPEYRPAWAGAAHWS 504 Query: 432 IIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGE 491 + + PL + L+A LLG D+S+ + +LI E+ GNPFF +E+ + L E L GE Sbjct: 505 TLRLEPLGPSDAQGLLAALLGEDRSLVPLKQLILEKTEGNPFFMEEVVQTLVEEKSLLGE 564 Query: 492 RGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDL 551 GRY A + +P T+Q +AARIDRL K+LL A AVIG F L+ + + Sbjct: 565 AGRYRIEETPATLHIPTTVQGVLAARIDRLPLDEKELLQALAVIGHEFPFSLIRRICGEA 624 Query: 552 SV--DEL------IDANLVDQVRFTAP-VEYAFRHPLIRTVAYESQLKSDXXXXXXXXXX 602 DEL ++A R P V Y+F+H L + VA S L Sbjct: 625 PARDDELRRLLAHLEAAEFIYERPAFPEVNYSFKHALTQEVAGRSLLTERRTTLHERTAQ 684 Query: 603 XXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIA 662 P + + +A H +G++ A + RAA A ++ A Sbjct: 685 AIEMLFPTRIADYCSELAHHYSQSGNIPKAVEYLHRAAQQALRHAAHHDAMNHLGAALAL 744 Query: 663 DALTAEDPHRA----AMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVAT 718 + P RA + ++ L + G + + +LC TG+ +P Sbjct: 745 LKGLPDTPVRAHWELTLLLSLGPVLMDVRGYGATEVGAIYTRALELCERTGEASPRFATQ 804 Query: 719 VGPAIDHV 726 +G + HV Sbjct: 805 LGLRMHHV 812 >tr|Q0B393|Q0B393_BURCM Tax_Id=339670 SubName: Full=Adenylate/guanylate cyclase;[Burkholderia ambifaria] Length = 1151 Score = 251 bits (642), Expect = 2e-64 Identities = 215/791 (27%), Positives = 334/791 (42%), Gaps = 77/791 (9%) Query: 7 CVACGAELRSIAKFCDECGSPV-------------------------------------- 28 C CG + A+FC CG+ + Sbjct: 28 CPQCGHDADPAARFCSNCGASLETTAAAPPPSRPSATELPPTPVHYTPDHLAERIRAEHA 87 Query: 29 ---VEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVD 85 E E K VT LFAD+ GS + + E ++ +V + Y G V Sbjct: 88 AMEARGEPAGERKTVTALFADMAGSTALIHDLDPEVAHRLIVPVVELMMEAVHYYEGYVA 147 Query: 86 KFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQ 145 K GDGI+A+FGAP A EDHA RA AAL +Q+ R+ + ++G+ LQ+RVG+++G+ Sbjct: 148 KSLGDGILALFGAPIAHEDHAQRALFAALRMQQAMRQHGDRIRLQEGIPLQIRVGVHTGE 207 Query: 146 VIVGEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVR 203 V+V I + L Y +G + +A R+E +A P +++SEST +L E A + Sbjct: 208 VVVRSIRTDDLHTEYDPLGHTIHIASRIEGIAAPTSILVSESTHKLAEGYFEFKALGATQ 267 Query: 204 IKGAEDAVPARRLLRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVG 259 +KG + +L + R + + VGRE E+ L LD G G VVG Sbjct: 268 LKGIPAPLCVYEVLGLGALRTRLQLAAHRGLARFVGRETEMEHLNRALDTMRAGHGRVVG 327 Query: 260 LVGPAGIGKTRLVAEAVQLAK--GLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLD 317 +VG AG+GK+RL E + ++ L +E FSV SH + +L++ QI+ D Sbjct: 328 VVGEAGVGKSRLFHEFKERSRRGALVLETFSV---SHGKAFPNLPLIELLKNYFQITTQD 384 Query: 318 DRSARARVREQI---------PDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXX 368 D R RE++ D G P + Sbjct: 385 D---ERRCREKVIGKALTLERSFEDLVPYVLYLLGIGEGGPVLAEMDPQIRRERTFDAIR 441 Query: 369 INVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVV 428 + + + ++P + ED+ W+D +++ L + +P R + LV YRPEY A Sbjct: 442 QLLVRESRNQPLHLLFEDLQWLDRETEAFLTYLIDHVPDARILLLVNYRPEYRPAWAGAA 501 Query: 429 GAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVL 488 + + PL + L+ LLG D+S+ + +LI E+ GNPFF +E+ + L E L Sbjct: 502 HWSTLRLEPLGPSDAQGLLTALLGEDRSLVPLKQLILEKTEGNPFFMEEVVQTLVEEKSL 561 Query: 489 TGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG 548 GE GRY A + +P T+Q +AARIDRL K+LL A AVIG F L+ + Sbjct: 562 LGEAGRYRIDETPATLHIPTTVQGVLAARIDRLPLDEKELLQALAVIGHEFPFSLIRRIC 621 Query: 549 IDLSV--DEL------IDANLVDQVRFTAP-VEYAFRHPLIRTVAYESQLKSDXXXXXXX 599 + DEL ++A R P V Y+F+H L + VA S L Sbjct: 622 GEAPARDDELRRLLAHLEAAEFIYERPAFPEVNYSFKHALTQEVAGRSLLTERRTTLHER 681 Query: 600 XXXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHAT 659 P + + +A H +G++ A + RAA A ++ A Sbjct: 682 TAQAIEMLFPTRIADYCSELAHHYSQSGNIPKAVEYLHRAAQQALRHAAHHDAMNHLGAA 741 Query: 660 KIADALTAEDPHRA----AMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLA 715 + P RA + ++ L + G + + +LC TG+ +P Sbjct: 742 LALLKGLPDTPVRAHWELTLLLSLGPVLMDVRGYGATEVGAVYTRALELCERTGEASPRF 801 Query: 716 VATVGPAIDHV 726 +G + HV Sbjct: 802 ATQLGLRMHHV 812 >tr|B1FEB2|B1FEB2_9BURK Tax_Id=396596 SubName: Full=Adenylate/guanylate cyclase with TPR repeats;[Burkholderia ambifaria IOP40-10] Length = 1151 Score = 251 bits (642), Expect = 2e-64 Identities = 215/791 (27%), Positives = 335/791 (42%), Gaps = 77/791 (9%) Query: 7 CVACGAELRSIAKFCDECGSPV-------------------------------------- 28 C CG + A+FC CG+ + Sbjct: 28 CPQCGHDADPAARFCSNCGASLETTAAAPPPSRPSAPELPPTPVHYTPDHLAERIRAEHA 87 Query: 29 ---VEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVD 85 E E K VT LFAD+ GS + + E ++ +V + Y G V Sbjct: 88 AMEARGEPAGERKTVTALFADMAGSTALIHDLDPEVAHRLIVPVVELMMEAVHYYEGYVA 147 Query: 86 KFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQ 145 K GDGI+A+FGAP A EDHA RA AAL +Q+ R+ + ++G+ LQ+RVG+++G+ Sbjct: 148 KSLGDGILALFGAPIAHEDHAQRALFAALRMQQAMRQHGDRIRLQEGIPLQIRVGVHTGE 207 Query: 146 VIVGEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVR 203 V+V I + L Y +G + +A R+E +A P +++SEST +L E A + Sbjct: 208 VVVRSIRTDDLHTEYDPLGHTIHIASRIEGIAAPTSILVSESTHKLAEGYFEFKALGATQ 267 Query: 204 IKGAEDAVPARRLLRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVG 259 +KG + +L + R + + VGRE E+ L LD G G VVG Sbjct: 268 LKGIPAPLCVYEVLGLGALRTRLQLAAHRGLARFVGRETEMEHLNRALDTMRAGHGRVVG 327 Query: 260 LVGPAGIGKTRLVAEAVQLAK--GLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLD 317 +VG AG+GK+RL E + ++ L +E FSV SH + +L++ QI+ D Sbjct: 328 VVGEAGVGKSRLFHEFKERSRRGALVLETFSV---SHGKAFPNLPLIELLKNYFQITTED 384 Query: 318 DRSARARVREQI---------PDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXX 368 D R RE++ D G P + Sbjct: 385 D---ERRCREKVIGKALTLERSFEDLVPYVLYLLGIGEGSPVLAEMDPQIRRERTFDAIR 441 Query: 369 INVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVV 428 + + + ++P + ED+ W+D +++ L + +P R + LV YRPEY A Sbjct: 442 QLLVRESRNQPLHLLFEDLQWLDRETEAFLTYLIDHVPDARILLLVNYRPEYRPAWAGAA 501 Query: 429 GAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVL 488 + + PL + L+A LLG D+S+ + +LI E+ GNPFF +E+ + L E L Sbjct: 502 HWSTLRLEPLGPSDAQGLLAALLGEDRSLVPLKQLILEKTEGNPFFMEEVVQTLVEEKSL 561 Query: 489 TGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG 548 G+ GRY A + +P T+Q +AARIDRL K+LL A AVIG F L+ + Sbjct: 562 LGDAGRYRIEETPATLHIPTTVQGVLAARIDRLPLDEKELLQALAVIGHEFPFSLIRRIC 621 Query: 549 IDLSV--DEL------IDANLVDQVRFTAP-VEYAFRHPLIRTVAYESQLKSDXXXXXXX 599 + DEL ++A R P V Y+F+H L + VA S L Sbjct: 622 GEAPARDDELRRLLAHLEAAEFIYERPAFPEVNYSFKHALTQEVAGRSLLTERRTTLHER 681 Query: 600 XXXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHAT 659 P + + +A H +G++ A + RAA A ++ A Sbjct: 682 TAQAIEVLFPTRIADYCSELAHHYSQSGNIPKAVEYLHRAAQQALRHAAHHDAMNHLGAA 741 Query: 660 KIADALTAEDPHRA----AMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLA 715 + P RA + ++ L + G + + +LC TG+ +P Sbjct: 742 LALLKGLPDTPVRAHWELTLLLSLGPVLMDVRGYGATEVGAIYTRALELCERTGEASPRF 801 Query: 716 VATVGPAIDHV 726 +G + HV Sbjct: 802 ATQLGLRMHHV 812 >tr|A9B3B1|A9B3B1_HERA2 Tax_Id=316274 SubName: Full=Adenylate/guanylate cyclase;[Herpetosiphon aurantiacus] Length = 1160 Score = 250 bits (639), Expect = 4e-64 Identities = 197/648 (30%), Positives = 301/648 (46%), Gaps = 43/648 (6%) Query: 7 CVACGAELRSIAKFCDECGSPVVEAETP-AEYKQVTVLFADVVGSMDIAAAVGLERLREI 65 C C + A+FC +CG + +A P +E ++VTV+FAD+VG IA + E + + Sbjct: 3 CTECLNLNPASARFCSQCGRMLADAPLPRSERRRVTVMFADLVGFSSIAEQLDAEAVHRL 62 Query: 66 MTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAA 125 + R +IE YGG VDKF GD IMAIFGAP A ED +RA AA + + A Sbjct: 63 INACFDRLVPIIEHYGGVVDKFIGDAIMAIFGAPLAHEDDPIRAVHAASAMLD----AIA 118 Query: 126 EVGDRDGVDLQLRVGLNSGQVIVGEIGS-SALGYTAVGVQVGMAQRMESVAPPGVVMLSE 184 E+ ++G+ L L +G+N+G VI G IGS Y+ +G V +A R++ +A G +++ Sbjct: 119 ELSQQEGLALGLHIGINTGVVIAGGIGSLGRQHYSVIGDAVNLAARLQDLASNGEILVGP 178 Query: 185 STARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFS----ESTLVGREWEL 240 T R+ A IKG + V + LR PR + +S +VGR EL Sbjct: 179 ETQRMTAHVFDFAALGEKAIKGRSEQVAVFK-LRGLNPRPSSGRGIKGLQSPMVGRSNEL 237 Query: 241 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAE--AVQLAKGLEVEVFSVFCESHATDV 298 +L A+ D RG VV VG AGIGK+RL+ E L + +V + C S+ + Sbjct: 238 DSLLAVTDNLAQQRGRVVIAVGEAGIGKSRLLTEWRNQSLEQLPQVVWYEARCLSYTQES 297 Query: 299 AFDVVAQLVRAVAQISGLDDRSARARVREQIPD---ADTQXXXXXXXXXGIADPAVEXXX 355 A+ ++ LVR++ +S D A QI AD + PA Sbjct: 298 AYALLRDLVRSLIGVSLNDGEDEMAAALHQIATALLADQADQVIPALSHLLLLPA-SRRF 356 Query: 356 XXXXXXXXXXXXXINVAQLALSR----PAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSM 411 V +L L++ P ++ +ED+HW DE S +L L + + Sbjct: 357 DELSPQALQALYITAVRRLVLAQGQHTPVIWSIEDIHWADEASVDVLQSLLQLHNDIPLV 416 Query: 412 ALVTYRPEYHGALRHVVGAQIIA-----------VAPLSDVETSTLVAELLGLDQSVTQI 460 L T RP+ R VVG +++ +APLS L+A LL D + Sbjct: 417 ILATSRPD-----REVVGWRLVEAARDLKGLELNLAPLSLANGRELIANLLHFDGLPEHL 471 Query: 461 GELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDR 520 I +A GNPFF +E+ R L +R + + + + ++ +P ++ +AARIDR Sbjct: 472 RTAILNKADGNPFFVEEVIRTLIDREAIMHDGNSWVALEAINQIELPDSVHGLLAARIDR 531 Query: 521 LSPPAKQLLVAAAVIGFRFGSDLLASL------GIDLSVDELIDANLVDQVRFTAPVEYA 574 L +QLL AAVIG RF ++A + + S+D L+D L+ + R Sbjct: 532 LPTELRQLLHIAAVIGRRFAIRVVAEVLGSTAERLSNSIDLLVDRELLRRDRTNPNGYLR 591 Query: 575 FRHPLIRTVAYESQLKSDXXXXXXXXXXXXXXXXPHSVDQHAVLIAEH 622 FRH L+ V Y + L+++ P ++ A +A H Sbjct: 592 FRHALVHEVVYSTTLQTERRRLHGVVGETLETLYPSRREELAAALANH 639 >tr|Q89K68|Q89K68_BRAJA Tax_Id=375 SubName: Full=Bll5043 protein;[Bradyrhizobium japonicum] Length = 1064 Score = 249 bits (637), Expect = 7e-64 Identities = 201/627 (32%), Positives = 295/627 (47%), Gaps = 58/627 (9%) Query: 7 CVACGAELRSIAKFCDECGS------------------------PVVEAETPAEYKQVTV 42 C C + +FC +CG+ P + ++ E K V+V Sbjct: 8 CPTCSTRVAREDRFCSQCGADLKRRVVEPGTQDRGAQVVQLRDHPPLRSKMLTENKHVSV 67 Query: 43 LFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTAL 102 LFADV S + E R + + +++ A +E YGGTV + GDG++A+FGAP A Sbjct: 68 LFADVCDSTALLQHSDPEEARNYLGKALNQLAEAVETYGGTVSQLLGDGLVALFGAPLAQ 127 Query: 103 EDHALRACLAALGVQEKARRLAAEVGDRDGV-DLQLRVGLNSGQVIVGEIGSSALG-YTA 160 EDHALRACLAAL K +R D GV LR+G+NSG+V+VG +G Y A Sbjct: 128 EDHALRACLAAL----KMQRATVPGHDVQGVASPTLRIGINSGEVLVGVVGQYDWSHYGA 183 Query: 161 VGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVA 220 G + +A R+E +APPG +++S +T RLV Q + T +I+G ++ + ++ Sbjct: 184 DGKTIHLASRLEKMAPPGGILVSAATQRLVAQQIETRSVGTRQIRGLDEPIELHEVVVET 243 Query: 221 EP-------RQPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVA 273 E R+ W + LVGRE L LA L+ G +GL G AGIGK+RLVA Sbjct: 244 ESSAAAPLTRKQRW---APLVGREDSLRILAGDLEVVRKGGMRTIGLCGDAGIGKSRLVA 300 Query: 274 E--AVQLAKGLEVEVFSV--FCESHATDVAFDVVAQLVRAVAQISGLDDR-SARARVREQ 328 + A ++G++V V + + A A D++A LV V Q++ D R SAR + E Sbjct: 301 DWTAALASEGMDVCVSQARGYASTRAYSAAADLIASLVGLV-QMNVTDVRQSARQALIEG 359 Query: 329 IPDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXIN--VAQLALSRPAVFVVED 386 P + G+A P + V + A S P V V+ED Sbjct: 360 WPAEGAEHLAAASDLLGLAAPDQAWLALNPVQRRRRIGEALLWLVRRRARSGPFVLVLED 419 Query: 387 VHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDVETSTL 446 V D S + L + + + V+YRP++ R + PL D + L Sbjct: 420 VFLADRESRRLFEALLPKLQELPVLVCVSYRPDFEHQWRQAPWFVERMIEPLHDGQMLRL 479 Query: 447 VAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCV 506 LLG D SV + + RA GNPFF +++ L + G L G G Y + E+ V Sbjct: 480 ARALLGDDPSVLGVMNELVARADGNPFFLEQLVITLIDDGSLEGTPGAYRLQRPLGELRV 539 Query: 507 PATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL-GIDLSVDELIDANLVDQV 565 P ++ A I AR DRL AK L AAAV+G DL+A++ +D++ E + A V Sbjct: 540 PGSIAAVIGARTDRLPEAAKSALEAAAVLGDPITRDLIATMQAVDIARAEELLALCVASG 599 Query: 566 RFTAPVE---------YAFRHPLIRTV 583 + P + +AFRH L+R V Sbjct: 600 LLSCPEQTSLSLEPQAFAFRHALVRDV 626 >tr|A8L7N2|A8L7N2_FRASN Tax_Id=298653 SubName: Full=Adenylate/guanylate cyclase;[Frankia sp.] Length = 1094 Score = 248 bits (633), Expect = 2e-63 Identities = 188/643 (29%), Positives = 291/643 (45%), Gaps = 39/643 (6%) Query: 7 CVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIM 66 C C E A+FC ECG+P+ A + K VT++F D+ GS DI + E L+++M Sbjct: 32 CPTCAEENPKRARFCSECGNPLPVAGNGSR-KTVTIMFVDITGSTDIGEKIDSEPLQQVM 90 Query: 67 TELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAE 126 + VI +GGTV+KF GD + A+FG P ED ALRA A+L ++ L A+ Sbjct: 91 WRFFTTVREVIHAHGGTVEKFIGDAVFAVFGIPVLHEDDALRAVRASLDIRAAMEELNAD 150 Query: 127 VGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSEST 186 + G+ L++R+G+N+G+V V G A G V +A R+E APP +++ +ST Sbjct: 151 LQREWGLRLRVRIGINTGEVTVA-------GGGATGDPVNVASRLEEAAPPDEILIGDST 203 Query: 187 ARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEP------RQPTWFSESTLVGREWEL 240 R + + + + + ++G + V A RL+ + +P R PT + ++GR E Sbjct: 204 YRFIRHSVTVSSVGPLVVQGKREPVRAHRLIGLVDPTAGPGSRAPTQGFAAPVIGRNRER 263 Query: 241 ATLAAMLDRSIGGRG-SVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVA 299 L + + R + ++GPAGIGK+R+V E Q A V + C S+ +A Sbjct: 264 RRLQDAFEAVVEERTCHLFTVLGPAGIGKSRMVGEFCQ-ATASRATVLTGRCLSYGEGIA 322 Query: 300 FDVVAQLVRAVAQISGLDDRSA---RARVREQIPDADTQXXXXXXXXXGIADPAVEXXXX 356 + + ++VR +S D SA R R++E + D P V Sbjct: 323 YWPLMEMVRQATGMSA--DESAPDGRLRLKELLADVPQAAEVVDALA-----PLVGLGGA 375 Query: 357 XXXXXXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTY 416 LA RP V +DVHW + ++ + L Sbjct: 376 ELGTQESFWAVRTFFQALAEKRPLVLWFDDVHWAEPTLLDLIEHVADWSRDAPILLLCLS 435 Query: 417 RPEYHGALRHVVGAQIIA----VAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNP 472 RPE R G ++ A +APL++ L+ L+G D + IT AAGNP Sbjct: 436 RPELLEDRREWGGGKLNATSMLLAPLTEARCHRLIRTLMGSDDLDPALVSRITTSAAGNP 495 Query: 473 FFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAA 532 F +++ L + G+L E R+ + ++ V VP T+ A +AAR+DRL PP +++L A Sbjct: 496 LFVEQMVAALVDDGLLRREGSRWIATGNLRGVTVPPTISALLAARLDRLEPPERRVLERA 555 Query: 533 AVIGFRFGSDLLASLG-------IDLSVDELIDANLVDQVRFTAP--VEYAFRHPLIRTV 583 AV+G RF D +A L + L+ LV R P Y F H L+R Sbjct: 556 AVVGERFYLDAVAELSDPAERPYVTEHCLSLVRKELVHPDRSDLPGVDAYRFLHVLLRDC 615 Query: 584 AYESQLKSDXXXXXXXXXXXXXXXXPHSVDQHAVLIAEHLEAA 626 AY++ K +H L+ HLE A Sbjct: 616 AYQATSKRQRADLHQRFAGWLQARMVGGPGEHDELVGYHLEQA 658 >tr|Q46SE1|Q46SE1_RALEJ Tax_Id=264198 SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase:Tetratricopeptide TPR_4;[Ralstonia eutropha] Length = 1141 Score = 247 bits (631), Expect = 4e-63 Identities = 198/639 (30%), Positives = 290/639 (45%), Gaps = 63/639 (9%) Query: 5 LVCVACGAELRSIAKFCDECGSPVVEAETPA----------------------------- 35 L C CG +FC ECG+ +V A P+ Sbjct: 26 LHCPTCGHAADPEDRFCAECGTSLVPAMEPSAEVQPAAVRAPIHYTPSHLVDRILAEQAA 85 Query: 36 ---------EYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDK 86 E K +T LFAD+ GS + + E R ++ ++ + Y G V K Sbjct: 86 MEARGASAGERKTITALFADMAGSTALIHDLDPEEARRLIDPVIDLMMEAVHHYEGYVAK 145 Query: 87 FTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQV 146 GDGI+A+FGAP A EDHA RA AAL +Q RR + V G+ LQ+RVG+++G+V Sbjct: 146 SLGDGILALFGAPIAHEDHAHRALYAALRMQAAMRRHSDRVRLEQGIPLQIRVGIHTGEV 205 Query: 147 IVGEIGSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRI 204 +V I L Y VG + +A RMES+A P +++SE T RL E A ++ Sbjct: 206 VVRSIRKDDLRTDYDPVGHTIHIASRMESIATPSSILVSEPTCRLTEGYFDFKALGATQV 265 Query: 205 KGAEDAVPARRLLRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVGL 260 KG DA ++R+ R ++ + VGR EL L L+ + G G +V + Sbjct: 266 KGMPDAFAVYEVVRLGALRTRLQVAQRRGLARFVGRHAELEQLRRALELAAAGHGQIVAV 325 Query: 261 VGPAGIGKTRLVAE--AVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDD 318 VG AG+GK+RL E AV + +E FSV SH A+ + +LV+ +I DD Sbjct: 326 VGEAGVGKSRLFYEFKAVSQRGCMVLETFSV---SHGKSFAYLPLIELVKNYFRIQDQDD 382 Query: 319 -RSARARVREQIPDAD---TQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQL 374 R R +V ++ D GI++P I + Sbjct: 383 ERQRREKVAGRMLMLDRTLEDVLPCMLDLLGISEPDSALPNMDPQIRRQRTFDAIVRLFI 442 Query: 375 --ALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQI 432 + ++P + ED+ W+D +++ L + IP R + L+ YRPEY H G Sbjct: 443 CESANQPLQLIFEDLQWLDSDTEAFLDVLVDRIPSARILLLLNYRPEYRHDW-HARGCYT 501 Query: 433 -IAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGE 491 + + PL E L+ LLG S+ + LI E+ GNPFF +E+ + L+E L GE Sbjct: 502 QLRLDPLGQAEAGELLTALLGDHPSLETLRALILEKTEGNPFFIEEVVQTLSEEKTLLGE 561 Query: 492 RGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLAS-LGID 550 G Y A + +P T++ +AARIDRL K LL + AVIG F L+ +G Sbjct: 562 SGHYHIEATPAALHIPTTVRGVLAARIDRLPSAEKNLLQSLAVIGKEFSLSLIEQVIGQP 621 Query: 551 LSVDELIDANL-VDQVRFTAP----VEYAFRHPLIRTVA 584 V + A L + + P VEY F+H L + VA Sbjct: 622 EDVLRPLLARLQAGEFIYERPAFPDVEYTFKHGLTQEVA 660 >tr|A6UFJ6|A6UFJ6_SINMW Tax_Id=366394 SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase;[Sinorhizobium medicae] Length = 1089 Score = 247 bits (631), Expect = 4e-63 Identities = 216/773 (27%), Positives = 346/773 (44%), Gaps = 73/773 (9%) Query: 7 CVACGAELRSIAKFCDECGSPVVEA------------------------ETPAEYKQVTV 42 C+ CG S + FC +CG+P +A A+ + +T+ Sbjct: 28 CLGCGYPCPSDSAFCPKCGAPTNDAGAEGKPTSRAASALTVKIKQPALPAVDADRRTITI 87 Query: 43 LFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTAL 102 LFAD+ G ++ + E ++ + EL ++ +GG VDKF GD ++A+FGAP A Sbjct: 88 LFADLSGFTALSEQIDPELMQALQNELFEELTEAVQSFGGFVDKFIGDALLALFGAPIAH 147 Query: 103 EDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGS-SALGYTAV 161 E+ RA AAL + E+A R+ R G L +G+N+G V+ G G+ SA Y+ Sbjct: 148 EEDPERALRAALDMVERASRMGERWQARAGAPPILHIGVNTGPVVTGGFGAGSAKSYSVT 207 Query: 162 GVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAE 221 G V AQR++S+A P V++ T RL V ++G ++P RL + E Sbjct: 208 GDTVNTAQRLQSMASPSEVLVGPLTQRLTRHAFVFETLGETMLRGKTGSIPVYRLKGLRE 267 Query: 222 PRQPTWFSE-----STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAV 276 +P E + L+GR+ EL + A LD + G +V LVG AGIGK+RLV E + Sbjct: 268 AARPARGLEALGLSTPLIGRKAELERMFASLDLACRGSAQLVRLVGEAGIGKSRLVNEFI 327 Query: 277 ----QLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQI-SGLDDRSARARVREQI-- 329 + V + C S + ++ +A +VR+ A + G +AR+ + + Sbjct: 328 ARIGDEQRFAAVAIRQAAC-SPLGEQSYGTLAAVVRSAAGMRQGGPVAETKARLSDLLGE 386 Query: 330 ----PDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINV---AQLALSRPAVF 382 D G+ P I +LAL P + Sbjct: 387 LGLNGDEAVSLTPLLLHVVGLGGPEGALRHVQPEQLRRQIFFAIRTIFERRLALG-PLLI 445 Query: 383 VVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY--HGALRHVVGAQIIAVAPLSD 440 VVED+HW D VS L + + Q R + + T+RP + + + +APL D Sbjct: 446 VVEDLHWADAVSLEALRFLMDRLEQQRLIMVFTHRPTFDMEQLDSRRISHTTLRLAPLDD 505 Query: 441 VETSTLVAELLG--LDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACS 498 L+A L G DQ++ +G I +RA GNP F +EI R E G+L + + + Sbjct: 506 NGGRKLLASLFGEKWDQTLNSLGSRILDRAGGNPLFIEEIVRGFIEDGILERDGLHWRAA 565 Query: 499 TDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL-----GIDLSV 553 + A V +PA++QA + AR DRL P A++L AAV+G RF + LLA++ I+ + Sbjct: 566 SSEAAVEIPASIQAILLARADRLPPEARRLAQEAAVLGPRFDATLLAAISAHPKNIETGL 625 Query: 554 DELIDANLVDQVRFTAPV---EYAFRHPLIRTVAYES---QLKSDXXXXXXXXXXXXXXX 607 D L DA ++++V + Y F L++ V Y++ Q +++ Sbjct: 626 DILCDAEIIEEVAAGGSIASRSYRFTQALLQNVIYQNLLLQRRTEMHGQVGMALEQSCGQ 685 Query: 608 XPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALT- 666 P ++ +L+ H + A ++R+A RA + + ALT Sbjct: 686 DPERLED--LLLLGHHFSLSPNRAKGARYLRSA----GDRARAVYANDDAIRHYQQALTA 739 Query: 667 -AEDPHRAAMCIAPRTR---LCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLA 715 A++P + ++ R R LCG R R + + V ATGD+A A Sbjct: 740 LADEPEPVELRLSLRERIADLCGTTGR-REAAHEHYRTVLVARRATGDRAGAA 791 >tr|B1T4T0|B1T4T0_9BURK Tax_Id=396597 SubName: Full=Adenylate/guanylate cyclase with TPR repeats;[Burkholderia ambifaria MEX-5] Length = 1063 Score = 246 bits (629), Expect = 6e-63 Identities = 205/725 (28%), Positives = 322/725 (44%), Gaps = 36/725 (4%) Query: 32 ETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDG 91 E E K VT LFAD+ GS + + E ++ +V + Y G V K GDG Sbjct: 6 EPAGERKTVTALFADMAGSTALIHDLDPEVAHRLIVPVVELMMEAVHYYEGYVAKSLGDG 65 Query: 92 IMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEI 151 I+A+FGAP A EDHA RA AAL +Q+ R+ + ++G+ LQ+RVG+++G+V+V I Sbjct: 66 ILALFGAPIAHEDHAQRALFAALRMQQAMRQHGDRIRLQEGIPLQIRVGVHTGEVVVRSI 125 Query: 152 GSSAL--GYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAED 209 + L Y +G + +A R+E +A P +++SEST +L E A ++KG Sbjct: 126 RTDDLHTEYDPLGHTIHIASRIEGIAAPTSILVSESTHKLAEGYFEFKALGATQLKGIPA 185 Query: 210 AVPARRLLRVAEPRQPTWFSE----STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAG 265 + +L + R + + VGRE E+ L+ LD G G VVG+VG AG Sbjct: 186 PLCVYEVLGLGALRTRLQLAAHRGLARFVGRESEMDHLSRALDTMRAGHGRVVGVVGEAG 245 Query: 266 IGKTRLVAEAVQLAK--GLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRSARA 323 +GK+RL E + ++ L +E FSV SH + +L++ QI+ DD Sbjct: 246 VGKSRLFHEFKERSRRGALVLETFSV---SHGKAFPNLPLIELLKNYFQITTQDD---ER 299 Query: 324 RVREQI---------PDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQL 374 R RE++ D G P + + + Sbjct: 300 RCREKVIGKALTLERSFEDLVPYVLYLLGIGEGGPVLAEMDPQIRRERTFDAIRQLLVRE 359 Query: 375 ALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIA 434 + ++P + ED+ W+D +++ L + +P R + LV YRPEY A + Sbjct: 360 SRNQPVHLLFEDLQWLDRETEAFLTYLIDHVPDARILLLVNYRPEYRPAWAGAAHWSTLR 419 Query: 435 VAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGR 494 + PL + L+ LLG D+S+ + +LI E+ GNPFF +E+ + L E L G+ GR Sbjct: 420 LEPLGPSDAQGLLTALLGEDRSLVPLKQLILEKTEGNPFFMEEVVQTLVEEKSLLGDAGR 479 Query: 495 YACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDLSV- 553 Y A + +P T+Q +AARIDRL K+LL A AVIG F L+ + + Sbjct: 480 YRIEEIPATLHIPTTVQGVLAARIDRLPLDEKELLQALAVIGHEFPFSLIRRICGEAPAR 539 Query: 554 -DEL------IDANLVDQVRFTAP-VEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXX 605 DEL ++A R P V Y+F+H L + VA S L Sbjct: 540 DDELRRLLAHLEAAEFIYERPAFPEVNYSFKHALTQEVAGRSLLTERRTTLHERTAQAIE 599 Query: 606 XXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADAL 665 P + + +A H +G++ A + RAA A ++ A Sbjct: 600 VLFPTRIADYCSELAHHYSQSGNIPKAVEYLHRAAQQALRHAAHHDAMNHLGAALALLKG 659 Query: 666 TAEDPHRA----AMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGP 721 + P RA + ++ L + G + + +LC TG+ + +G Sbjct: 660 LPDTPVRAHWELTLLLSLGPVLMDVRGYGATEVGAIYTRALELCERTGEASQRFATQLGL 719 Query: 722 AIDHV 726 + HV Sbjct: 720 RMHHV 724 >tr|Q2K8B4|Q2K8B4_RHIEC Tax_Id=347834 SubName: Full=Putative adenylate/guanylate cyclase protein;[Rhizobium etli] Length = 1081 Score = 245 bits (625), Expect = 2e-62 Identities = 185/632 (29%), Positives = 292/632 (46%), Gaps = 48/632 (7%) Query: 5 LVCVACGAELRSIAKFCDECGSPV----------------VEAETPAEYKQVTVLFADVV 48 L C ACG + FC CG+ + EA++ A+ + VTVLFAD+ Sbjct: 26 LSCAACGYPCQPDFAFCPRCGASISGKAQPAAKPAIETAPAEADSDADRRPVTVLFADLC 85 Query: 49 GSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALR 108 G ++ + E +R + EL +E YGG VDKF GD ++A+FGAP A ED +R Sbjct: 86 GFTSLSEQIDPEVMRALQNELFEEMTLAVEAYGGFVDKFVGDALLALFGAPVAHEDDPVR 145 Query: 109 ACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIG-SSALGYTAVGVQVGM 167 A AAL + ++A + R GV L+L +G+NSG V+ G G +S Y+ G V Sbjct: 146 ALNAALDMIDRAAAVGTRWQSRAGVPLRLHIGINSGPVVTGGFGAASTKSYSVTGDTVNT 205 Query: 168 AQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTW 227 AQR++S+A +++ T RL + ++G V RL + E Sbjct: 206 AQRLQSMAGENDILVGPLTYRLTRHAFAFESLGAQALRGKSGNVLVHRLTGLLEAPHTAR 265 Query: 228 FSES-----TLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGL 282 ES +VGR+ +++ L LD + GG +V L+G AGIGK+RL +E V +A Sbjct: 266 GLESFGLRAPMVGRDADMSRLLTCLDLACGGAAQLVRLIGEAGIGKSRLASEFVGVAADA 325 Query: 283 E----VEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDR-------SARARVREQIPD 331 + + + C S + ++ +A +VR+ I DDR + R + D Sbjct: 326 DRFPGLAIRKATC-SPLGEQSYGTLAAVVRSAYGIGERDDRDKTRELLTTGFRALDLRSD 384 Query: 332 ADTQXXXXXXXXXGIADP--AVEXXXXXXXXXXXXXXXXINVAQLALSRPAVFVVEDVHW 389 G+ DP A+ + P + V+ED+HW Sbjct: 385 DIDALLPLFLHVLGLGDPDGALRHIEPEQLRRQIFYAVRTVFERRLAQGPLLLVIEDLHW 444 Query: 390 IDEVSDSMLADFLAVIPQTRSMALVTYRP--EYHGALRHVVGAQIIAVAPLSDVETSTLV 447 D S +L + + ++R M L YRP + + V + +APL + L+ Sbjct: 445 ADAASLEVLRFMMDRLERSRLMLLAIYRPTLQTDPLNSNRVSVTVQRLAPLLAADGQKLL 504 Query: 448 AELLGLDQS--VTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVC 505 A G + + I +RA GNP F +EI R L + G L + R+ + + A+V Sbjct: 505 AAFFGEGHGKLPAPMRKRILDRAGGNPLFIEEILRGLIDMGTLHNDGQRWHVAAEDADVD 564 Query: 506 VPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL-----GIDLSVDELIDAN 560 +P LQA + AR+DRL ++L AAV+G +F + LL ++ G+D ++D L DAN Sbjct: 565 IPVNLQALLLARVDRLPQEIRRLAQEAAVVGPKFDTALLRTVATDPAGVDAALDYLCDAN 624 Query: 561 LVDQVR---FTAPVEYAFRHPLIRTVAYESQL 589 +++++R Y F L+ VAY + L Sbjct: 625 IIEELRGPDAAISPGYRFSQTLMHDVAYHNLL 656 >tr|B3Q0E9|B3Q0E9_RHIE6 Tax_Id=491916 SubName: Full=Putative adenylate/guanylate cyclase protein; EC=4.6.1.1;[Rhizobium etli] Length = 1081 Score = 243 bits (619), Expect = 9e-62 Identities = 184/632 (29%), Positives = 292/632 (46%), Gaps = 48/632 (7%) Query: 5 LVCVACGAELRSIAKFCDECGS-----------PVVE-----AETPAEYKQVTVLFADVV 48 L C ACG + FC +CG+ P++E +++ A+ + VTVLFAD+ Sbjct: 26 LSCAACGYACQPDFAFCPKCGASISGKASPAPKPIIEVVATKSDSDADRRPVTVLFADLC 85 Query: 49 GSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALR 108 G ++ + E +R + EL +E YGG VDKF GD ++A+FGAP A ED +R Sbjct: 86 GFTTLSEQIDPETMRVLQNELFEEMTRAVETYGGFVDKFVGDALLALFGAPVAHEDDPVR 145 Query: 109 ACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGS-SALGYTAVGVQVGM 167 A AAL + ++A + R GV L+L +G+NSG V+ G G+ A Y+ G V Sbjct: 146 ALGAALDMIDRAAAVGTRWQSRAGVPLRLHIGINSGPVVTGGFGAVGAKSYSVTGDTVNT 205 Query: 168 AQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTW 227 AQR++S+A +++ T RL + ++G V RL+ + + Sbjct: 206 AQRLQSMAGENDILVGPLTYRLTRHAFAFDSLGAQTLRGKSGNVHVHRLIGLLDAPHTAR 265 Query: 228 FSES-----TLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGL 282 ES ++GR+ EL+ L + LD + G +V L+G AGIGK+RL E V LA Sbjct: 266 GLESFGLQAPMIGRDAELSRLLSCLDLACDGAAQLVRLIGEAGIGKSRLATEFVGLAANA 325 Query: 283 E----VEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDR-------SARARVREQIPD 331 + + C S + ++ +A +VR+ I DDR + R + D Sbjct: 326 TRFPGLAIRKATC-SPLGEQSYGTLAAVVRSAYGIGERDDRDRTRQLLTTGFRALDLTQD 384 Query: 332 ADTQXXXXXXXXXGIADP--AVEXXXXXXXXXXXXXXXXINVAQLALSRPAVFVVEDVHW 389 G+ DP A+ + P + V+ED+HW Sbjct: 385 DVDGLLPLFLHVLGLGDPDGALRHIEPEQLRRQIFYAIRTVFERRLAQGPLLLVIEDLHW 444 Query: 390 IDEVSDSMLADFLAVIPQTRSMALVTYRP--EYHGALRHVVGAQIIAVAPLSDVETSTLV 447 D S +L + + ++R M LV YRP + + V + + PL + L+ Sbjct: 445 ADAASLEVLRFMMDRLERSRLMLLVIYRPTQQTDPLNSNRVNVTVQRLGPLFAADGQRLL 504 Query: 448 AELLGLDQSVTQIG--ELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVC 505 A G + + I +RA GNP F +EI R L + G L + R+ + D +V Sbjct: 505 AAFFGEAHGKLPVAMRKRILDRAGGNPLFIEEILRGLIDMGTLHHDGQRWHVAADDTDVA 564 Query: 506 VPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL-----GIDLSVDELIDAN 560 +P LQA + AR+DRL ++L AAV+G +F + LL ++ ID ++D L DAN Sbjct: 565 IPVNLQALLLARVDRLPQEMRRLAQEAAVVGPKFDTALLRAVATDPAAIDAALDYLCDAN 624 Query: 561 LVDQVR---FTAPVEYAFRHPLIRTVAYESQL 589 +++++R Y F L+ V Y++ L Sbjct: 625 IIEELRGPDAGGSPGYRFSQTLMHDVIYQNLL 656 >tr|Q98GL0|Q98GL0_RHILO Tax_Id=381 SubName: Full=Mlr3277 protein;[Rhizobium loti] Length = 1121 Score = 240 bits (612), Expect = 6e-61 Identities = 205/652 (31%), Positives = 300/652 (46%), Gaps = 73/652 (11%) Query: 7 CVACGAELRSIAKFCDECGSPV------------------------------VEAE---- 32 C CG +FC +CG+ V +E+E Sbjct: 50 CANCGYPCAPDFEFCPKCGASVGGAAKAVERPAPTPSRTIVPPSRTPSLLANIESEDGPY 109 Query: 33 --TPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGD 90 + A+ + VTVLFAD+ G ++ + E ++ + +L + +GG VDKF GD Sbjct: 110 PVSDADRRTVTVLFADLCGFTTLSEQLDPEVMQALQNDLFKELTAAVRNFGGFVDKFIGD 169 Query: 91 GIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGE 150 ++A+FGAP A ED RA AAL + + RL E G L L +G+N+G V+ G Sbjct: 170 ALLALFGAPVAHEDDPERALRAALDMIARTARL-GENAPHSGTPLLLHIGINTGPVVTGG 228 Query: 151 IG-SSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAED 209 +G +A Y+ G V AQR++S+A PG V++ E T RL V ++G Sbjct: 229 LGIGTAKSYSVTGDTVNTAQRLQSLAAPGEVLVGELTHRLTRHAFSYEPLGDVVLRGKAG 288 Query: 210 AVPARRL-LRVAEPRQPTWFS----ESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPA 264 V RL +A PR + ++GR+ EL + A LD++ GG +V LVG A Sbjct: 289 TVLVHRLDAPLAAPRAARGLEALGLSAPMIGRDAELHRMLASLDQACGGSAQLVRLVGEA 348 Query: 265 GIGKTRLVAEAVQLA----KGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDD-R 319 GIGK+RLV E V + V V C S + +F + +VR+ A + D+ Sbjct: 349 GIGKSRLVKEFVARIGDEDRFRNVAVRQATC-SPLGERSFGALGAVVRSAAGMMQNDNGD 407 Query: 320 SARARVREQIPDADTQ------XXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINV-- 371 R ++ + D Q G+ DP + Sbjct: 408 EMRGKLAGLLTDLGLQGEEAKRLMPLLYHVLGLGDPDATLQHVEPEQLRRQILYAVRTII 467 Query: 372 -AQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPE-YHGAL-RHVV 428 +LALS P + VVED+HW D VS L + + +TR M LVT+RPE HG L V Sbjct: 468 ERRLALS-PLLIVVEDLHWADAVSLEALRFVMDRLERTRLMLLVTHRPEPDHGQLDSSRV 526 Query: 429 GAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGEL---ITERAAGNPFFAQEITRELAER 485 + ++PLS + +L+ L G + V G L I ERA GNP F +EI R L +R Sbjct: 527 SHTALRLSPLSRDDGRSLLTALFG-ESWVNSSGGLVDQILERAGGNPLFLEEIVRGLIDR 585 Query: 486 GVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLA 545 GVL E R+ A +PAT+QA + ARIDRL ++L AAVIG RF + LL Sbjct: 586 GVLVREGQRWRTVAGEAATGIPATIQAMLLARIDRLPQEVRRLAQEAAVIGPRFDATLLK 645 Query: 546 SLGID-----LSVDELIDANLVDQVRFTAPVE---YAFRHPLIRTVAYESQL 589 ++ D + L DA ++++V + V Y F L++ V Y++ L Sbjct: 646 AVTADPGRLEAGCELLCDAEIIEEVAGSGSVSSQGYRFTQTLLQDVIYQNLL 697 >tr|Q2JH00|Q2JH00_FRASC Tax_Id=106370 SubName: Full=Adenylate/guanylate cyclase;[Frankia sp.] Length = 1142 Score = 239 bits (611), Expect = 7e-61 Identities = 187/644 (29%), Positives = 291/644 (45%), Gaps = 41/644 (6%) Query: 7 CVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIM 66 C C + A+FC CG+P+ + A K VT++F D+ GS DI + E L+++M Sbjct: 57 CPTCAEDNHERARFCSGCGNPLPTPGSGAR-KTVTIMFVDITGSTDIGERIDSEPLQQVM 115 Query: 67 TELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAE 126 + VI +GG+V+KF GD + A+FG P ED ALRA AAL ++ L A+ Sbjct: 116 WRFFTTVREVIYIHGGSVEKFIGDAVFAVFGIPVLHEDDALRAVRAALDIRAAMEALNAD 175 Query: 127 VGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSEST 186 + G+ L++R+G+N+G+V V G G V +A R+E APP +++ ++T Sbjct: 176 LQREWGLKLRVRIGINTGEVTVA-------GGGVTGDPVNVASRLEHAAPPDEILIGDTT 228 Query: 187 ARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEP------RQPTWFSESTLVGREWEL 240 R + + + + ++G D + RL+ + +P R PT + ++GR E Sbjct: 229 YRFIRHSVTVSPLGPLVVQGKRDPLRVHRLIGLVDPTAGPGSRAPTHGFTAPVIGRNRER 288 Query: 241 ATLAAMLDRSIGGRG-SVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVA 299 L + + R + ++GPAGIGK+R+V E A V + C S+ +A Sbjct: 289 RRLQDAFEAVVEERTCHLFTVLGPAGIGKSRMVGEFC-AAMANRATVLTGRCLSYGEGIA 347 Query: 300 FDVVAQLVRAVAQISGLDDRSA---RARVREQIPDADTQXXXXXXXXXGIADPAVEXXXX 356 + + ++VR +S D SA R R+RE + D TQ P V Sbjct: 348 YWPLMEMVRQATGLSA--DESAPDGRRRLRELL-DGVTQAAEIVEALA----PLVGLGGA 400 Query: 357 XXXXXXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTY 416 LA RP + +DVHW + +L + M L Sbjct: 401 ELGPQESFWAVRSFFQALAARRPLILWFDDVHWAEPTLLDLLENIADWSRDAPIMLLCLA 460 Query: 417 RPEYHGALRHVVGAQIIA----VAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNP 472 RPE R G ++ A +APL++ L+ L+G D + IT AAGNP Sbjct: 461 RPELLEERRDWGGGKLNATSMLLAPLTEARCQRLIRTLMGSDDLDPALVSRITTSAAGNP 520 Query: 473 FFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAA 532 F +++ L + G+L E R+ + + V VP T+ + +AAR+DRL PP +++L A Sbjct: 521 LFVEQMVAALVDDGLLRREGSRWIATGSLRNVTVPPTISSLLAARLDRLDPPERRVLERA 580 Query: 533 AVIGFRFGSDLLASLGIDLSVDELIDAN--------LVDQVRFTAPVEYAFR--HPLIRT 582 A++G RF D + L D S ++ A+ LV R P AFR H L+R Sbjct: 581 AIVGERFYLDAVIDLS-DPSEQPMVAAHCLSLVRKELVHPDRSDLPGVEAFRFLHVLLRD 639 Query: 583 VAYESQLKSDXXXXXXXXXXXXXXXXPHSVDQHAVLIAEHLEAA 626 AY+S K +H L+ HLE A Sbjct: 640 CAYQSTAKRQRADLHQRFAQWLQTRLEGGPGEHDELVGYHLEQA 683 >tr|C6AXV1|C6AXV1_RHILS Tax_Id=395491 SubName: Full=Adenylate/guanylate cyclase with TPR repeats;[Rhizobium leguminosarum bv. trifolii] Length = 1080 Score = 239 bits (611), Expect = 7e-61 Identities = 185/633 (29%), Positives = 290/633 (45%), Gaps = 51/633 (8%) Query: 5 LVCVACGAELRSIAKFCDECGS-----------PVVEA----ETPAEYKQVTVLFADVVG 49 + C ACG + FC CG+ P +EA E A+ + VTVLFAD+ G Sbjct: 26 ITCAACGNACQPDFAFCPSCGASISGKVQPASKPKIEALPQSEGDADRRPVTVLFADLCG 85 Query: 50 SMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRA 109 ++ + E +R + EL +E YGG VDKF GD ++A+FGAP A ED +RA Sbjct: 86 FTTLSEQIDPEVMRVLQNELFEEMTQAVEAYGGFVDKFVGDALLALFGAPVAHEDDPVRA 145 Query: 110 CLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGS-SALGYTAVGVQVGMA 168 AAL + +A + R GV L+L +G+NSG V+ G G+ S Y+ G V A Sbjct: 146 LGAALDMIGRATEVGERWHARAGVPLRLHIGINSGPVVTGGFGAVSTKSYSVTGDTVNTA 205 Query: 169 QRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWF 228 QR++S+A +++ T RL + ++G V RL ++E Sbjct: 206 QRLQSMAGENDILVGPLTYRLTRHAFAFDSLGAQTLRGKSGNVLVHRLTGLSEAPHTARG 265 Query: 229 SES-----TLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLA---- 279 ES ++GR+ E++ L LD + GG +V L+G AGIGK+RLV E V +A Sbjct: 266 LESLGLQAPMIGRDTEMSRLLTCLDLACGGAAQLVRLIGEAGIGKSRLVNEFVAIAGNAA 325 Query: 280 --KGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDD-------RSARARVREQIP 330 +GL + + S + ++ + +VR+ I DD + R + Sbjct: 326 RFQGLAIRKATC---SPLGEQSYGTLGAVVRSAYGIGERDDLDRARQLLATGFRALDLTQ 382 Query: 331 DADTQXXXXXXXXXGIADP--AVEXXXXXXXXXXXXXXXXINVAQLALSRPAVFVVEDVH 388 + G+ DP A+ + P + V+ED+H Sbjct: 383 EEVEGLLPLFLHVLGLGDPDGALRYIEPEQLRRQIFYGVRTVFERRLAQGPLLLVIEDLH 442 Query: 389 WIDEVSDSMLADFLAVIPQTRSMALVTYRP--EYHGALRHVVGAQIIAVAPLSDVETSTL 446 W D S +L + + ++R M L YRP + + V + +APL + L Sbjct: 443 WADAASLEVLRFMMDRLERSRLMLLAVYRPTSQTDPLDSNRVSVTVQRLAPLFAADGQKL 502 Query: 447 VAELLGLDQSVTQI--GELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEV 504 +A G DQ + + I +RA GNP F +EI R L + G L + R+ + + +V Sbjct: 503 LAAFFGEDQGKLPVTMRKRILDRAGGNPLFIEEILRALIDMGTLHNDGQRWHVAAEDTDV 562 Query: 505 CVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL-----GIDLSVDELIDA 559 +P LQA + AR+DRL ++L AAV+G +F + LL ++ ID ++D L DA Sbjct: 563 DIPVNLQALLLARVDRLPQDIRRLAQEAAVVGPKFDTALLRTIATDPAAIDAALDHLCDA 622 Query: 560 NLVDQVR---FTAPVEYAFRHPLIRTVAYESQL 589 N+++++R Y F L+ V Y + L Sbjct: 623 NIIEELRGPDAGGSPGYRFSQTLMHDVIYHNLL 655 >tr|B5ZPV2|B5ZPV2_RHILW Tax_Id=395492 SubName: Full=Adenylate/guanylate cyclase with TPR repeats;[Rhizobium leguminosarum bv. trifolii] Length = 1081 Score = 236 bits (603), Expect = 6e-60 Identities = 182/631 (28%), Positives = 285/631 (45%), Gaps = 46/631 (7%) Query: 5 LVCVACGAELRSIAKFCDECGS-----------PVVE-----AETPAEYKQVTVLFADVV 48 L C ACG + FC CG+ P +E +++ A+ + VTVLFAD+ Sbjct: 26 LSCAACGCACQPDFAFCPRCGAAISGQVPPAPKPSIEVVPHKSDSDADRRPVTVLFADLC 85 Query: 49 GSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALR 108 G ++ + E +R + EL +E YGG VDKF GD ++A+FGAP A ED +R Sbjct: 86 GFTTLSEQIDPEVMRVLQNELFEEMTQAVEAYGGFVDKFVGDALLALFGAPVAHEDDPVR 145 Query: 109 ACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGS-SALGYTAVGVQVGM 167 A AAL + +A + R GV L+L +G+NSG V+ G G+ S Y+ G V Sbjct: 146 ALGAALDMIRRATDVGDRWRSRAGVPLRLHIGINSGPVVTGGFGAVSTKSYSVTGDTVNT 205 Query: 168 AQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTW 227 AQR++S+A +++ T RL + ++G V RL + E Sbjct: 206 AQRLQSMAGENDILVGPLTYRLTRHAFAFDSLGAQTLRGKSGNVIVHRLAGLLEAPHTAR 265 Query: 228 FSES-----TLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGL 282 ES ++GR+ EL+ L LD + GG +V L+G AGIGK+RLV E V A Sbjct: 266 GLESFGLQAPMIGRDGELSRLLTCLDLACGGAAQLVRLIGEAGIGKSRLVNEFVGTAGDA 325 Query: 283 EVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRSARARVRE---------QIPDAD 333 + ++ + + L V G+ +R A+ R+ + D Sbjct: 326 DRFPGLAIRKATCSPLGEQSYGTLAAVVRSAYGIGERDDLAKTRQLLTTGFRALDLTQED 385 Query: 334 TQ-XXXXXXXXXGIADP--AVEXXXXXXXXXXXXXXXXINVAQLALSRPAVFVVEDVHWI 390 + G+ DP A+ + P + V+ED+HW Sbjct: 386 VEGLLPLFLHVLGLGDPDGALRHIEPEQLRRQIFYAVRTVFERRLAQGPLLLVIEDLHWA 445 Query: 391 DEVSDSMLADFLAVIPQTRSMALVTYRP--EYHGALRHVVGAQIIAVAPLSDVETSTLVA 448 D S +L + + ++R M L YRP + V + + PL + L+A Sbjct: 446 DVASLEVLRFMMDRLERSRLMLLAIYRPTSQTDPLNSDRVNVTVQRLDPLFAADGQKLLA 505 Query: 449 ELLGLDQSVTQIG--ELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCV 506 G S + + I +RA GNP F +EI R L + G L + R+ + D ++V + Sbjct: 506 AFFGESHSKLPVAMRKRILDRAGGNPLFIEEILRGLIDMGTLHHDGHRWHVAADDSDVDI 565 Query: 507 PATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL-----GIDLSVDELIDANL 561 P LQA + AR+DRL ++L AAV+G +F + LL ++ G+D ++D L DAN+ Sbjct: 566 PVNLQALLLARVDRLPQEMRRLAQEAAVVGPKFDTALLRTVASDPAGVDAALDFLCDANI 625 Query: 562 VDQVR---FTAPVEYAFRHPLIRTVAYESQL 589 ++++R Y F L+ V Y + L Sbjct: 626 IEELRGPDAAGSPGYRFSQTLMHDVIYHNLL 656 >tr|Q92YL0|Q92YL0_RHIME Tax_Id=382 (cyaI3)SubName: Full=CyaI3 adenylate/guanylate cyclase; EC=4.6.1.1;[Rhizobium meliloti] Length = 1159 Score = 233 bits (595), Expect = 5e-59 Identities = 205/735 (27%), Positives = 334/735 (45%), Gaps = 42/735 (5%) Query: 26 SPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVD 85 +PV+ E AE +Q+TV+F D+V S +++ + E + E++ AG I R+ G V Sbjct: 104 TPVINPE--AERRQLTVMFVDLVESTRLSSRLDPEEMGELLRGYQRAVAGAIARFEGHVA 161 Query: 86 KFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQ 145 K+ GDG++A FG P A ED A RA A L + R+L G+ L+ RVG+ +G Sbjct: 162 KYMGDGVLAYFGYPRAHEDEAERAVRAGLAAIDAVRKLQPPHGE----TLEARVGIATGL 217 Query: 146 VIVGEI--GSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVR 203 V+VGE+ +A T +G +A R++SVA PG V+++ +T +L+ L Sbjct: 218 VVVGELIGEGAAREETVIGETPNLAARLQSVAEPGAVVVASATRQLIGGLFDLAELGFHP 277 Query: 204 IKGAEDAVPARRLL--RVAEPRQPTWFSES--TLVGREWELATLAAMLDRSIGGRGSVVG 259 +KG ++PA R+L AE R + S LVGRE ++ L + G+G VV Sbjct: 278 LKGFAASIPAWRVLGESSAESRFEAFHGASLTPLVGREHDIGLLLKRWEAVKKGKGRVVL 337 Query: 260 LVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCES-HATDVAFDVVAQLVRAVAQISGLDD 318 L G GIGK+RLV + +G S +C H T + V+ L RA A + D Sbjct: 338 LAGEPGIGKSRLVRALRRRLEGEPHTTVSHYCSPYHQTSPLYPVIRLLERA-AGFAAEDP 396 Query: 319 RSARARVREQIPDADTQXXXXXXXXXG--IADPAVEXXXXXXXXXXXXXXXXINV----- 371 + E + + ++ PA + + V Sbjct: 397 PEVKLSKLEALLTQSIEEVADAAPLLAALLSVPADDRYQPLELSPHRQKKRMLEVLVDQL 456 Query: 372 AQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQ 431 LA +P + V EDVHW D S +L + + + + L+T+R E+ Sbjct: 457 IGLAARQPILAVYEDVHWADPTSLELLDLVVDRVQDSPVLVLITFRTEFLPPWTRYPHVT 516 Query: 432 IIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGE 491 ++ ++ LS + + +V L G T++ + I + G P F +E+TR + E +L E Sbjct: 517 VLTLSRLSRRQGAEMVDRLTGRRALPTEVLDQIVAKTDGVPLFVEELTRAILETSLLKAE 576 Query: 492 RGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG--- 548 YA + ++ + +PATL ++ AR+DRL+ PA++++ AA IG F +LL + Sbjct: 577 GDHYALARPLSAISIPATLHESLLARLDRLA-PAREVMQVAAAIGREFSHELLVTAAPLQ 635 Query: 549 ---IDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXX 605 ++ ++++LI + LV + + Y+F+H L+R AY + +++ Sbjct: 636 ASEVEEALEDLIASGLVFRHGTPPQLTYSFKHALVRDAAYATLVRTKRQRLHAAIATAIE 695 Query: 606 XXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRA-----AAWATNQDVRAARVSWEHATK 660 P V L+A+H AG L A + +RA A AT + + E Sbjct: 696 QRFPEMVQTQPELLAQHYAEAGRLEPAVNYWLRAGQAEIARSATTEAISHLTRGLELLEG 755 Query: 661 IAD---ALTAEDPHRAAMCIAPRTRLCGIAWR-GRFNSSSGFDEVRQLCNATGDKAPLAV 716 + D L E + A+ +A T A GR N+ R LC GDK+ L Sbjct: 756 LPDDAARLRKELELQVALSVALMTAKGWAAPEVGRANA-----RARNLCERLGDKSRLFP 810 Query: 717 ATVGPAIDHVYQDRL 731 G + HV + L Sbjct: 811 VLYGDWVFHVVRAEL 825 >tr|Q1MGI8|Q1MGI8_RHIL3 Tax_Id=216596 SubName: Full=Putative adenylate cyclase; EC=4.6.1.1;[Rhizobium leguminosarum bv. viciae] Length = 1084 Score = 232 bits (591), Expect = 2e-58 Identities = 180/631 (28%), Positives = 284/631 (45%), Gaps = 46/631 (7%) Query: 5 LVCVACGAELRSIAKFCDECGS-----------PVVEA-----ETPAEYKQVTVLFADVV 48 + C ACG + FC CG+ P +EA E A+ + VTVLFAD+ Sbjct: 29 VTCAACGNPCQPDFAFCPACGASIPSKVQAASKPKIEAVPSKSEGDADRRPVTVLFADLC 88 Query: 49 GSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALR 108 G ++ + E +R + EL +E YGG VDKF GD ++A+FGAP A ED +R Sbjct: 89 GFTTLSEQIDPEVMRVLQNELFEEMTQAVEAYGGFVDKFVGDALLALFGAPVAHEDDPVR 148 Query: 109 ACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGS-SALGYTAVGVQVGM 167 A AAL + +A ++ R GV L+L +G+NSG V+ G G+ S Y+ G V Sbjct: 149 ALGAALDMIGRATQVGERWHARAGVPLRLHIGINSGPVVTGGFGAVSTKSYSVTGDTVNT 208 Query: 168 AQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTW 227 AQR++S+A +++ T RL + ++G V RL ++E Sbjct: 209 AQRLQSMAGENDILVGPLTYRLTRHAFAFESLGAQALRGKSGNVLVHRLTGLSEAPHTAR 268 Query: 228 FSES-----TLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGL 282 ES ++GR+ E++ L LD + GG +V L+G AGIGK+RLV E V +A Sbjct: 269 GLESFGLQAPMIGRDTEMSRLLTCLDLACGGAAQLVRLIGEAGIGKSRLVNEFVAIASNA 328 Query: 283 EVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRSARARVRE---------QIPDAD 333 ++ + + L V G+ +R R R+ + D Sbjct: 329 ARFQGLAIRKATCSPLGEQSYGTLGAVVRSAYGIGERDDLDRARQLLATGFRALDLTQED 388 Query: 334 TQ-XXXXXXXXXGIADP--AVEXXXXXXXXXXXXXXXXINVAQLALSRPAVFVVEDVHWI 390 + G+ DP A+ + P + V+ED+HW Sbjct: 389 VEGLLPLFLHVLGLGDPDGALRYIEPEQLRRQIFYAVRTVFERRLAQGPLLLVIEDLHWA 448 Query: 391 DEVSDSMLADFLAVIPQTRSMALVTYRP--EYHGALRHVVGAQIIAVAPLSDVETSTLVA 448 D S +L + + ++R M L YRP + + V + +APL + L+A Sbjct: 449 DAASLEVLRFMMDRLERSRLMLLAVYRPTSQTDPLDSNRVSVTVQRLAPLFAADGQKLLA 508 Query: 449 ELLGLDQSVTQI--GELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCV 506 G + + + I +RA GNP F +E R L + G L + R+ + + +V + Sbjct: 509 AFFGESYAKLPVTMRKRILDRAGGNPLFIEETLRALIDMGTLHNDGQRWHVAAEDTDVDI 568 Query: 507 PATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASL-----GIDLSVDELIDANL 561 P LQA + AR+DRL ++L AAV+G +F + LL ++ ID ++D L DAN+ Sbjct: 569 PLNLQALLLARVDRLPQDIRRLAQEAAVVGPKFDTALLRTIATDPAAIDAALDHLCDANI 628 Query: 562 VDQVR---FTAPVEYAFRHPLIRTVAYESQL 589 ++++R Y F L+ V Y + L Sbjct: 629 IEELRGPDAGGSPGYRFSQTLMHDVIYHNLL 659 >tr|C4CPA9|C4CPA9_9CHLR Tax_Id=479434 SubName: Full=Adenylate/guanylate cyclase family protein;[Sphaerobacter thermophilus DSM 20745] Length = 1159 Score = 232 bits (591), Expect = 2e-58 Identities = 198/663 (29%), Positives = 295/663 (44%), Gaps = 49/663 (7%) Query: 36 EYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAI 95 E + VT+LF DV GS IA + E EIM IERYGGT+ + GD ++A Sbjct: 20 ERRVVTILFCDVAGSTSIAEQLDPEEWAEIMHMAFDALMRPIERYGGTIARLMGDAVLAF 79 Query: 96 FGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSA 155 FGAP A ED RA LAAL + + L V G++ +R+G+N+G V+VGE GS+A Sbjct: 80 FGAPRAHEDDPRRAILAALDIVAEVAPLRDLVRQTYGLEFNVRIGINTGDVVVGEFGSAA 139 Query: 156 LG-YTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPAR 214 + YTA+G + +A R++ A PG +++ EST R + ++G A A Sbjct: 140 MNEYTAMGDAINLAARLQQQAEPGSILVGESTYRATAPFFRFEPVGRLALRGKARAENAY 199 Query: 215 RLLRVAEPRQPTW---FSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRL 271 R+L+ + W ++ LVGR E+ L + G+G V LVG AG+GK+RL Sbjct: 200 RVLQSIDVSGRLWDIAGLDAPLVGRAAEMDLLCRAYEGLSAGKGHVACLVGDAGMGKSRL 259 Query: 272 VAE-----AVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDD-RSARARV 325 ++ +G +V S A + + Q +R V I+ D S A+V Sbjct: 260 ISHLRGYWEDDRGRGGDVAWLEHRVVSFAGLEPYGALRQRLRRVFGIARHDTAESVHAKV 319 Query: 326 REQI----PDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQLALSR--- 378 P + G+ D A + L R Sbjct: 320 MRATQHFPPATRERATRIITAVLGVGDEASPAQAISEGIAADAFRRELTSVMRELLRGWN 379 Query: 379 ---PAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGAL---------RH 426 P VFV +D H ID S+ ++ D L +I + ++ +RPE + R+ Sbjct: 380 RGKPVVFVSDDHHLIDLASEELVVDLLQLIDDAPVLFVLAFRPELGSPVWKIIETCRERY 439 Query: 427 VVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERG 486 G I +APL+ E L L+ D ++ E + E+A GNP F +EI R L ++G Sbjct: 440 ESGYSEIWLAPLAADERMALFDSLVRSDDG-QRLRERVLEKAGGNPLFIEEIVRSLIDQG 498 Query: 487 VL------TGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFG 540 L ++ R A D+++V +P+TL A I R+DRL+P +Q L A+VIG F Sbjct: 499 YLEPCDDCLEQQWRVAPHADLSQVTIPSTLHALILERVDRLAPEVRQHLQLASVIGRSFS 558 Query: 541 SDLLASL--GIDLSVDELIDANLVDQVRFTAPV---EYAFRHPLIRTVAYESQLKSDXXX 595 LL ++ D L +D + A + Y+FRHPLI+ V Y + ++ Sbjct: 559 RSLLEAISDAPGTVADHLAVLTKLDLITPDADLGVGAYSFRHPLIQEVVYGTLIRRFRSE 618 Query: 596 XXXXXXXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSW 655 +D+ A I H AGD A GW ++AA RA V Sbjct: 619 VHRRIGDAIERLYAGRLDERAGEIGWHYSQAGD-ERAVGWLIKAAE-------RAGSVGE 670 Query: 656 EHA 658 HA Sbjct: 671 PHA 673 >tr|Q89HN2|Q89HN2_BRAJA Tax_Id=375 SubName: Full=Bll5958 protein;[Bradyrhizobium japonicum] Length = 1106 Score = 229 bits (584), Expect = 1e-57 Identities = 181/594 (30%), Positives = 289/594 (48%), Gaps = 42/594 (7%) Query: 32 ETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDG 91 ++ A + +TVLFAD+ G ++ + E ++ + L ++ +GG VDKF GD Sbjct: 94 DSEANRRTITVLFADLSGFTAMSERLDPEVMQTLQNGLFEELTAAVQSFGGFVDKFIGDA 153 Query: 92 IMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEI 151 ++A+FGAP A ED RA AAL + ++ RL+ G L L VG+N+G V+ G + Sbjct: 154 LLALFGAPAAHEDDPERAVRAALDMIDRTARLSERAKAYAGSPLLLHVGINTGHVVAGGL 213 Query: 152 GSS-ALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDA 210 G+ A Y+ G V AQR++S+A PG V++ T RL + V +KG + Sbjct: 214 GAGVAKSYSVTGDTVNTAQRLQSMAAPGEVLVGPLTHRLTRHAFSYDSLGEVSLKGKMGS 273 Query: 211 VPARRLLRVAE-PRQ----PTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAG 265 V RL + PR T + L+GR+ ELA + LD + GG +V LVG AG Sbjct: 274 VLVHRLNEPLDTPRAARGLDTLGLNAPLIGRDAELARMIGSLDLACGGAAQLVRLVGEAG 333 Query: 266 IGKTRLVAEAVQLAKGLE----VEVFSVFCESHATDVAFDVVAQLVRA---VAQISGLDD 318 IGKTRLV E V + + V + C S + ++ +A ++R+ +AQ +G + Sbjct: 334 IGKTRLVREFVARIRDQDRFAGVAIRQAAC-SPLGEQSYGTLAAVLRSAYGIAQKAGATE 392 Query: 319 RSARARVREQI------PDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVA 372 A A+V E + D + G+ DP I Sbjct: 393 --AEAKVAEALSELGLATDEADRLMPLYLHVLGLGDPNAVLRHVEPEQLRRQIFFAIRTV 450 Query: 373 ---QLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRP----EYHGALR 425 +LALS P + +VED+HW D VS L + + +TR M L T+RP + G+ R Sbjct: 451 FERRLALS-PLLIIVEDLHWADAVSLEALRFLMDRLERTRLMLLFTHRPMLELDLFGSSR 509 Query: 426 HVVGAQIIAVAPLSDVETSTLVAELL--GLDQSVTQIGELITERAAGNPFFAQEITRELA 483 + + + PL D + L+A G + ++ I +RA GNP F +EI R L Sbjct: 510 --ISHATLRLPPLGDADGQRLLAAYFSHGWREPPGRLFSRILDRAGGNPLFLEEIIRGLI 567 Query: 484 ERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDL 543 E G L + ++ ++D A +PA++QA + AR+DRL ++L AAVIG RF + Sbjct: 568 EAGTLERDGVQWRMTSDEAAADIPASIQALLLARLDRLPHQVRRLAQEAAVIGPRFDAAA 627 Query: 544 LASLG-----IDLSVDELIDANLVDQVRFTAPVE---YAFRHPLIRTVAYESQL 589 L + ++ ++ L DA +V+++ + + Y F +++ V Y++ L Sbjct: 628 LGAAATEPARVEAGLELLCDAEIVEEIAGSNSISLRTYRFTQTMLQDVIYQNLL 681 >tr|Q0RUJ9|Q0RUJ9_FRAAA Tax_Id=326424 SubName: Full=Putative adenylate cyclase; EC=4.6.1.1;[Frankia alni] Length = 1067 Score = 225 bits (573), Expect = 2e-56 Identities = 180/644 (27%), Positives = 286/644 (44%), Gaps = 41/644 (6%) Query: 7 CVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIM 66 C C + A+FC CG+P+ A + A K VT++F D+ S DI + E L+++M Sbjct: 3 CPTCAEDNPERARFCSGCGNPLPTAGSGAR-KTVTIMFVDIARSTDIGEKIDSEPLQQVM 61 Query: 67 TELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAE 126 + VI +GG+V+KF GD + A+FG P ED ALRA +AL ++ L A+ Sbjct: 62 WRFFTTVREVIYNHGGSVEKFIGDAVFAVFGIPVLHEDDALRAVRSALDIRAAMEALNAD 121 Query: 127 VGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSEST 186 + ++ G+ L++R+G+N+G+V V G G V +A R+ES APP +++ ++T Sbjct: 122 LQEKWGLRLRVRIGINTGEVTVA-------GGGVTGDAVNVAARLESAAPPDEILIGDTT 174 Query: 187 ARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEP------RQPTWFSESTLVGREWEL 240 R + + + + ++G D + RL + +P R + ++GR E Sbjct: 175 HRFIRHSVTVTPLGPLVVQGKRDPLRVHRLTGLVDPTAGPGSRAQIHGFTAPVIGRNRER 234 Query: 241 ATLAAMLDRSIGGRG-SVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVA 299 L + + R + ++G AGIGK+R+V E + V + C S+ +A Sbjct: 235 RRLQDAFEAVVEERACHLFTVLGSAGIGKSRMVGEFC-TSMATRATVLTGRCLSYGEGIA 293 Query: 300 FDVVAQLVRAVAQISGLD-DRSA---RARVREQIPDADTQXXXXXXXXXGIADPAVEXXX 355 + + ++VR Q +GL D SA R R+RE + P V Sbjct: 294 YWPLMEMVR---QATGLTADESAPDGRRRLRELLDGVGQAAEIVEALA-----PLVGLGG 345 Query: 356 XXXXXXXXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVT 415 LA RP + +DVHW + ++ + M L Sbjct: 346 AELGPQESFWAVRSFFQALAARRPLILWFDDVHWAEPTLLDLIENIADWSRDAPIMLLCL 405 Query: 416 YRPEYHGALRHVVGAQIIA----VAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGN 471 R E R G + A +APL++ L+ L+G D + IT AAGN Sbjct: 406 ARQELLEDRRDWGGGKFNATSMLLAPLTEARCQRLIRSLMGSDDLDPALVTRITTSAAGN 465 Query: 472 PFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVA 531 P F +++ L + G+L E R+ + + V VP T+ + +AAR+DRL PP +++L Sbjct: 466 PLFVEQMVAALVDDGLLRREGSRWIATGSLRNVTVPPTISSLLAARLDRLDPPERRVLER 525 Query: 532 AAVIGFRFGSDLLASLG-------IDLSVDELIDANLVDQVRFTAPVEYAFR--HPLIRT 582 AAV+G RF D + L +++ L+ LV R P AFR H L+R Sbjct: 526 AAVVGERFYLDAVIDLSDPAERSMVNVHCLNLVRKELVHPDRSDLPGVEAFRFLHVLLRD 585 Query: 583 VAYESQLKSDXXXXXXXXXXXXXXXXPHSVDQHAVLIAEHLEAA 626 AYES K +H L+ HLE A Sbjct: 586 CAYESTAKRRRADLHQQFAHWLQARLVGGPGEHDELVGYHLEQA 629 >tr|A8LF50|A8LF50_FRASN Tax_Id=298653 SubName: Full=Adenylate/guanylate cyclase with TPR repeats;[Frankia sp.] Length = 1285 Score = 222 bits (566), Expect = 1e-55 Identities = 216/746 (28%), Positives = 312/746 (41%), Gaps = 90/746 (12%) Query: 2 TTALVCVACGAELRSIAKFCDECGSPVVEAETP----AEYKQVTVLFADVVGSMDIAAAV 57 T LVC CG +FC CG + +TP AE + VTVLF D+ A Sbjct: 8 TGPLVCPRCGTPTVPGGRFCFNCGLRFTQTDTPRAEAAERRVVTVLFGDLSDFTAWAEDR 67 Query: 58 GLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQ 117 ER+ E+ +++ A ++ GG VD +GDGIMA+FGAPTA ED RA AA +Q Sbjct: 68 DPERVGEVTDRVLAALAREVDEVGGRVDNLSGDGIMAVFGAPTAHEDDPERAVRAAAAMQ 127 Query: 118 EKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPP 177 E ARRL + G D L LRVG+N+G+V+ G +AL YT +G V A R+ A Sbjct: 128 ETARRLIKDEGG-DSSPLGLRVGVNTGEVLAGV--QAALSYTVIGDTVNTAARLSGAAAV 184 Query: 178 GVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRL--LRVAEPRQPTWFSESTLVG 235 G V T A + +KG + VPA L LR + +P ++T +G Sbjct: 185 GTVYAGRDTVTATRSVATWRDLPPLVLKGKREPVPAYELVSLRPSNIARPGLADDATFIG 244 Query: 236 REWELATLAAMLDRSI-GGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLE----------- 283 RE ELA L+ + G+ + ++G AGIGKTRL E + A+ Sbjct: 245 REQELAELSRYFAGVVDAGQPDMAVVIGEAGIGKTRLARELAETAEATAGATVLWGRTVR 304 Query: 284 ----------VEVFSVFCESHATDVAFDVVAQLVRAVAQI----------SGLDDR---- 319 +++ C D V ++ R VA + SG+ DR Sbjct: 305 HGDVRDLAPLIDLIRGACGITDGDTLDRVADRVRRTVAGLTHPIFETKLPSGIGDRLLGM 364 Query: 320 -----SARARVREQIPDAD-TQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQ 373 R P D AD AVE + ++ Sbjct: 365 LGVPPDRRPSAGATTPPGDPVGRASHGEAVQRAADDAVE-------------TVGLLLSA 411 Query: 374 LALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRS-MALVTYRPEYHGALRHVVGAQI 432 LA+ P + VV+D+ W + S L L + T S ++ +VGA+ Sbjct: 412 LAVRNPVLVVVDDLEW----ATSRLTTALRRLTTTLSGPVMLVLLDRESPQFSDLVGARR 467 Query: 433 IAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVL---- 488 IA++PL + L+ + LG + R GNPFF E+ L +RG+L Sbjct: 468 IALSPLPESAARALLKDYLGEPGLSRATQAELLARVHGNPFFLTELLNLLVDRGLLHQVP 527 Query: 489 --TGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLAS 546 GE R+ +A +PA +Q+ +AARID L AK L AAAV+G RF ++ L Sbjct: 528 DPGGEGMRWVLEGSLAATVLPAGVQSVLAARIDDLDAAAKAALRAAAVLGPRFPAEALQV 587 Query: 547 LG------IDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXX 600 +G ++ ++ L + LV R + F HP+ R VAY K + Sbjct: 588 VGERPAAEVERALSVLTERQLVRPPR-QGETLWRFVHPMARDVAYSGLPKVERARRHATA 646 Query: 601 XXXXXXXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHA-T 659 S + + +A H A DL A+ AW +AR + HA Sbjct: 647 ARWGVTAMIGSSREVSTFVATHALRAYDLAASMALPAGDPAW-------SAREAGFHAHV 699 Query: 660 KIADALTAEDPHRAAMCIAPRTRLCG 685 ++A + A D HRAA + R G Sbjct: 700 RLARSALARDDHRAAADLLADARRLG 725 >tr|A6UA40|A6UA40_SINMW Tax_Id=366394 SubName: Full=Sterile alpha motif SAM protein;[Sinorhizobium medicae] Length = 1122 Score = 221 bits (562), Expect = 4e-55 Identities = 203/667 (30%), Positives = 304/667 (45%), Gaps = 46/667 (6%) Query: 35 AEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMA 94 AE +Q+TV+F D+VGS ++A + E LR+ + + A ++ RY G V K+ GDG++ Sbjct: 80 AERRQLTVMFCDLVGSTALSARLDPEDLRQSIVAYRACATEIVGRYDGFVAKYMGDGVLV 139 Query: 95 IFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEI--G 152 FG P A E+ A RA A L V E RL D G L +R+G+ +G V+VG+I Sbjct: 140 YFGYPQAHEEDAERAVRAGLAVVEAVDRL-----DAAGEHLAVRIGIATGLVVVGDIIGT 194 Query: 153 SSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVP 212 A + VG +A R++ +A G V+++E+T L+ L + IKG A Sbjct: 195 GEAEECSVVGETPNLAARLQELAGSGTVVIAEATRALLRGQFKLESIGLRPIKGFSGAAE 254 Query: 213 ARRLLRVAEPRQPTWFSES-----TLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIG 267 A R+L E R F LVGR+ ELA L ++ +G VV L G AGIG Sbjct: 255 AFRVL--GEVRGDDRFEAGHATVLPLVGRDRELALLVDRWTQAKANKGQVVLLEGEAGIG 312 Query: 268 KTRLVAEAVQLAKGLEVEVFSV---FCESHATDVAF-DVVAQLVRAVA----QISGLDDR 319 K+RL AV L + L E S+ F + + A V+AQL + S + Sbjct: 313 KSRL---AVALRERLCREPHSLLRYFASPYYVNSALRPVIAQLEQEAGFEREDSSVVKLA 369 Query: 320 SARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINV-----AQL 374 RA + EQ+ + ++ GI P + ++V A+L Sbjct: 370 KLRALIAEQMGEV-SEALPLLAELLGI--PGTDRCPILDLAPQQRKNRTVDVLIAQLARL 426 Query: 375 ALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIA 434 A +P + V+ED HW+D S + F+ I Q + +VT+RPE+ R + Sbjct: 427 AAKQPVLLVLEDAHWLDASSLELFGLFVNQIRQLPVLLVVTHRPEFVPPWRSYRHVTKVV 486 Query: 435 VAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGR 494 + L V LV L G + + I G P + +E+T+ + E G+L + Sbjct: 487 LNRLERVHAQLLVERLAGGKALPAGVLDYILANTDGVPLYLEELTKTMLESGLLEVAGDQ 546 Query: 495 YACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG------ 548 + + + + +P TL ++ AR+DRL AK + A IG F +L+A+L Sbjct: 547 FGLTAHMPPLAIPVTLYDSLMARLDRLG-KAKVVAQIGACIGREFSYELIAALAALNEHE 605 Query: 549 IDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXXXXX 608 + +D+L+ LV + Y+F+H L+R AY+S LKS Sbjct: 606 LQRRLDQLVATELVFRRGSPPDAIYSFKHALVRDTAYQSLLKSRRRELHRRIAQVFEELA 665 Query: 609 PHSVDQHAVLIAEHLEAAGDL-HAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALT- 666 PH V L+A HL AG+L A WH RAA AT + A V H K D L Sbjct: 666 PHVVFAQPELLAHHLTEAGELPQAVVFWH-RAAEHATERAANAEAVG--HLAKALDLLAQ 722 Query: 667 -AEDPHR 672 E+P R Sbjct: 723 MPENPER 729 >tr|Q92Y97|Q92Y97_RHIME Tax_Id=382 (cyaI4)SubName: Full=CyaI4 adenylate/guanylate cyclase;[Rhizobium meliloti] Length = 1118 Score = 219 bits (558), Expect = 1e-54 Identities = 195/718 (27%), Positives = 312/718 (43%), Gaps = 36/718 (5%) Query: 32 ETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDG 91 E AE +Q+TV+F D+VGS +A+ + +E LREI+ + I+R+GG V K+ GDG Sbjct: 83 EAGAERRQLTVMFCDLVGSTALASRLDVEDLREIIGAYQQCVSDTIKRFGGFVAKYMGDG 142 Query: 92 IMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEI 151 ++ FG P A ED A RA A L + + L E+ D LQ+R+G+ +G V+VG+I Sbjct: 143 VLVYFGYPQAHEDDAERAVRAGLALIDIVNEL--ELSD----PLQVRIGIATGIVVVGDI 196 Query: 152 --GSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAED 209 A +G +A R++ +A P V++ E T L+ T+ +KG + Sbjct: 197 VGFGEARERGVIGETPNIAARLQGLAEPDTVVIGERTHHLLGHLFDFRDLGTLEVKGYSE 256 Query: 210 AVPARRLLR--VAEPRQPTWFSE--STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAG 265 + A ++LR + + R E + LVGRE E+ L R+ G G V+ LVG G Sbjct: 257 PIRAYQVLRPSILDSRFEALHGERLTPLVGRENEIEALRHCWQRAKGIEGQVILLVGEPG 316 Query: 266 IGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVA-FDVVAQLVRAVAQISGLDDRSARAR 324 IGK+R+ ++ + FC H + A + ++ QL RA A++S DD S + Sbjct: 317 IGKSRITVAVLEEIANEQRTHLCYFCSPHHSGSALYPIIRQLERA-AEMSPDDDTSTKLD 375 Query: 325 VREQIPDADTQXXXXXXXXXGIAD-------PAVEXXXXXXXXXXXXXXXXINVAQLALS 377 E + A + + P + + LA Sbjct: 376 KLETLLAATSTAAEDCSLVSDLLSLPSSGRFPTFDLSPQQRKSRTLQALVR-QLEALAGR 434 Query: 378 RPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAP 437 P V + EDVHWID S +L + I + +VT+RPE+ ++ + Sbjct: 435 EPVVMIFEDVHWIDPTSLELLDRTVERIRMLPVLLVVTFRPEFTPPWSGQPHVSMMTLGR 494 Query: 438 LSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYAC 497 L + LV +LG + + I ER G P + +E T+ +AE + E Sbjct: 495 LGQRDGVALVEHVLGQQDLPAEAIQGIVERTDGVPLYLEEFTKAVAE---MCAEGDHAQS 551 Query: 498 STDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG------IDL 551 + A + +PATL A++ AR+DRL AK + AAVIG F DLLA++ + Sbjct: 552 TASSASLGIPATLHASLMARLDRLG-AAKNVAQIAAVIGREFSHDLLAAVAPYAATELRA 610 Query: 552 SVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXXXXXPHS 611 +D+L + +V + A Y F+H L++ AY + L+ P Sbjct: 611 FIDQLTSSGMVFRRGTAADSLYLFKHALVQDAAYNTLLRRPRQQLHGKIARTLEELFPGR 670 Query: 612 VDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVS-WEHATKIADAL---TA 667 + ++A H AG A + + A A + + + K +AL + Sbjct: 671 AAREPEVLAHHFAKAGQAARAIDYWLIAGKQAAQRSANLEAIDHFSRGLKALEALPLGSE 730 Query: 668 EDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDH 725 +D A+ A T L + + + + R LC GD A L G + H Sbjct: 731 KDWKELALQTALGTALISVHGYAASQTGAAYARARILCQKFGDAAALHATLSGEFVYH 788 >tr|Q68M96|Q68M96_RHIME Tax_Id=382 (rtsD)SubName: Full=RtsD;[Rhizobium meliloti] Length = 1118 Score = 219 bits (557), Expect = 1e-54 Identities = 195/718 (27%), Positives = 312/718 (43%), Gaps = 36/718 (5%) Query: 32 ETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDG 91 E AE +Q+TV+F D+VGS +A+ + +E LREI+ + I+R+GG V K+ GDG Sbjct: 83 EAGAERRQLTVMFCDLVGSTALASRLDVEDLREIIGAYQQCVSDTIKRFGGFVAKYMGDG 142 Query: 92 IMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEI 151 ++ FG P A ED A RA A L + + L E+ D LQ+R+G+ +G V+VG+I Sbjct: 143 VLVYFGYPQAHEDDAERAVRAGLALIDIVNEL--ELSD----PLQVRIGIATGIVVVGDI 196 Query: 152 --GSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAED 209 A +G +A R++ +A P V++ E T L+ T+ +KG + Sbjct: 197 VGFGEARERGVIGETPNIAARLQGLAEPDTVVIGERTHHLLGHLFDFRDLGTLEVKGYSE 256 Query: 210 AVPARRLLR--VAEPRQPTWFSE--STLVGREWELATLAAMLDRSIGGRGSVVGLVGPAG 265 + A ++LR + + R E + LVGRE E+ L R+ G G V+ LVG G Sbjct: 257 PIRAYQVLRPSILDSRFEALHGERLTPLVGRENEIEALRHCWQRAKGIEGQVILLVGEPG 316 Query: 266 IGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVA-FDVVAQLVRAVAQISGLDDRSARAR 324 IGK+R+ ++ + FC H + A + ++ QL RA A++S DD S + Sbjct: 317 IGKSRITVAVLEEIANEQRTHLCYFCSPHHSGSALYPIIRQLERA-AEMSPDDDTSTKLD 375 Query: 325 VREQIPDADTQXXXXXXXXXGIAD-------PAVEXXXXXXXXXXXXXXXXINVAQLALS 377 E + A + + P + + LA Sbjct: 376 KLETLLAATSTAAEDCSLVSDLLSLPSSGRFPTYDLSPQQRKSRTLQALVR-QLEALAGR 434 Query: 378 RPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAP 437 P V + EDVHWID S +L + I + +VT+RPE+ ++ + Sbjct: 435 EPVVVIFEDVHWIDPTSLELLDRTVERIRMLPVLLVVTFRPEFTPPWSGQPHVSMMTLGR 494 Query: 438 LSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYAC 497 L + LV +LG + + I ER G P + +E T+ +AE + E Sbjct: 495 LGQRDGVALVEHVLGQQDLPAEAIQGIVERTDGVPLYLEEFTKAVAE---MCAEGDHAQS 551 Query: 498 STDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG------IDL 551 + A + +PATL A++ AR+DRL AK + AAVIG F DLLA++ + Sbjct: 552 TASSASLGIPATLHASLMARLDRLG-AAKNVAQIAAVIGREFSHDLLAAVAPYAATELRA 610 Query: 552 SVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXXXXXPHS 611 +D+L + +V + A Y F+H L++ AY + L+ P Sbjct: 611 FIDQLTSSGMVFRRGTAADSLYLFKHALVQDAAYNTLLRRPRQQLHGKIARTLEELFPGR 670 Query: 612 VDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVS-WEHATKIADAL---TA 667 + ++A H AG A + + A A + + + K +AL + Sbjct: 671 AAREPEVLAHHFAKAGQAARAIDYWLIAGKQAAQRSANLEAIDHFSRGLKALEALPLGSE 730 Query: 668 EDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDH 725 +D A+ A T L + + + + R LC GD A L G + H Sbjct: 731 KDWKELALQTALGTALISVHGYAASQTGAAYARARILCQKFGDAAALHATLSGEFVYH 788 >tr|Q2J511|Q2J511_FRASC Tax_Id=106370 SubName: Full=Adenylate/guanylate cyclase;[Frankia sp.] Length = 1204 Score = 215 bits (548), Expect = 2e-53 Identities = 226/741 (30%), Positives = 317/741 (42%), Gaps = 76/741 (10%) Query: 2 TTALVCVACGAELRSIAKFCDECGSPVVEAETPA----EYKQVTVLFADVVGSMDIAAAV 57 T L C C + +FC CG E+PA E + VTVLF D+ A Sbjct: 8 TGPLRCPRCSSAAVPGGRFCYHCGLEFTSVESPAVDASERRVVTVLFGDLSDFTAWAEDR 67 Query: 58 GLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQ 117 ER+ E+ +++ A I+ GG VD TGDGIMA+FGAPTA ED RA AA +Q Sbjct: 68 DPERVGEMTDRVLAALAHEIDEVGGRVDNLTGDGIMAVFGAPTAHEDDPERAVRAAAAMQ 127 Query: 118 EKARR--LAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVA 175 E RR L + GD DG L LRVG+N+G+V+ G +AL YT +G V A R+ + A Sbjct: 128 ETVRRLVLTSTGGDDDG-RLGLRVGVNTGEVLAGV--QAALSYTVIGDTVNTAARLSAAA 184 Query: 176 PPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRL--LRVAEPRQPTWFSESTL 233 G V TA A + +KG + VPA L LR + +P ++ Sbjct: 185 TIGTVYAGRETALATRSVATWRELPDLVLKGKREPVPAYELVSLRPSNVARPGLADDAMF 244 Query: 234 VGREWELATLAAMLDRSIGGRGSVVGLV-GPAGIGKTRLVAEAVQLA------------- 279 +GR+ ELA+L + D + + V L+ G AGIGKTRL E A Sbjct: 245 LGRDAELASLTDLFDLVVANQSPEVALITGEAGIGKTRLAIELACRAERTPGTTVLWGRT 304 Query: 280 ------KGLEVEVFSVFCESHATD-VAFDVVAQLVRAVAQISGLDDRSARARVREQIPD- 331 +GL V V TD + D VA VR ++GL + AR+ I D Sbjct: 305 VRHGDGRGLAPLVDVVRNACGVTDGDSLDRVANRVRRT--VAGLAHPHSGARLPPGIADR 362 Query: 332 --------ADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVA----QLALSRP 379 D + G DPA VA LA S P Sbjct: 363 LLLLLGVPLDRRPAVATAAAPG--DPAARASHIAEAEQRSVDATVDAVALLLGALASSGP 420 Query: 380 AVFVVEDVHW-IDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPL 438 + +++D+ W ++SD+M A+ + L P G L H+ IA+ PL Sbjct: 421 ILVMIDDLEWATSQLSDAMSRLASALSGPILLVLLDRTGPRLAG-LPHI---HRIALRPL 476 Query: 439 SDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVL-------TGE 491 S +S L+ + LG Q + + R GNPFF E+ L +RG+L GE Sbjct: 477 SLEASSRLLQDHLGGVQLEPRGRADLLSRVHGNPFFLVELLNLLIDRGMLHQSAETTNGE 536 Query: 492 RGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLG--- 548 + + E +PA +Q+ +AARID L P AK +L AAAV+G RF ++ L + Sbjct: 537 WPGWVLEGSLTEATLPAGVQSVLAARIDDLDPVAKAVLRAAAVLGPRFPAEALPVVDERP 596 Query: 549 ---IDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDXXXXXXXXXXXXX 605 + ++ L + LV R T + F HP+ R AY K + Sbjct: 597 AEEVTRALRVLTERQLVRPPRAT-ETRWRFVHPMARDAAYAGLPKVERARRHATAARWGV 655 Query: 606 XXXPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHA-TKIADA 664 S + +A H A DL A+ + AW ++R+S HA ++A Sbjct: 656 TAMVGSSRAVSTFVANHALRAYDLAASMNLPITDPAW-------SSRMSGFHAHVRLARE 708 Query: 665 LTAEDPHRAAMCIAPRTRLCG 685 A D HRAA + R G Sbjct: 709 ALARDDHRAAADLLANARRLG 729 >tr|Q3A5C7|Q3A5C7_PELCD Tax_Id=338963 SubName: Full=Predicted ATPase, putative adenylate/guanylate cyclase activity;[Pelobacter carbinolicus] Length = 1134 Score = 214 bits (544), Expect = 4e-53 Identities = 166/571 (29%), Positives = 255/571 (44%), Gaps = 16/571 (2%) Query: 36 EYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAI 95 E +QVT LFAD+ G ++ A+G E + ++M + + G+V + TGDGI A+ Sbjct: 79 ERRQVTALFADLKGYTPLSEALGEEAIFKVMERVYEGMITAVLEEEGSVQELTGDGIFAL 138 Query: 96 FGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSS- 154 FGAP ALED LRAC AAL +Q K + L ++ GV R+G+++G VIVG +G+ Sbjct: 139 FGAPIALEDAPLRACRAALALQNKLKVLGEQLERELGVRPLARIGIHTGPVIVGTLGTDL 198 Query: 155 ALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPAR 214 + + AVG + +A R+ES+A PG V +S +T RL + V +IKG + Sbjct: 199 RMEFKAVGDTINLASRLESIADPGCVFISATTHRLADPFIVCSCVGERKIKGKKQPQQVY 258 Query: 215 RLLRVAEPR----QPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTR 270 RL + E + L GR EL L ++ +V ++G AG+GK+R Sbjct: 259 RLESIKEHAVRFDAALQRGLTPLAGRSEELDLLHHYQEKVGRNTLHLVLVIGEAGVGKSR 318 Query: 271 LVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRSARARVREQ-- 328 LV E + + V C S + ++ LV+ + +I DDRS R Q Sbjct: 319 LVHEFKERMQSRRVLFLQSNCTSCGSSISLMPFIHLVKDLFRIQDDDDRSVIKRKLTQGL 378 Query: 329 ----IPDADTQXXXXXXXXXGIADPAVEXXXXXXXXXXXXXXXXINVAQLALSRPAVFVV 384 + A A+ + + P + V+ Sbjct: 379 ELFGMDSAAATPYLMTLIGFHETGNALRGLDAKIVGERTREILVDLLRNRSRLTPTILVI 438 Query: 385 EDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDVETS 444 ED+HWID S+ +L Q + L T RP + + + + + PLS T Sbjct: 439 EDLHWIDPASEKLLGQMAREKGQMPLLILCTTRPSFTSPWSLLENVREMQLKPLSRESTM 498 Query: 445 TLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEV 504 +V LL D + +I + NP + +E+TR L E G + C E+ Sbjct: 499 HMVRALLDCDTIDESLARVIFQETGCNPLYTEEMTRFLLENGAIRRLGRTATCEFSAGEI 558 Query: 505 CVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDL---LASLG--IDLSVDELIDA 559 VP T+ + R+DRL K +L AAVIG RF L ++ LG D + EL Sbjct: 559 EVPPTVLDLLQTRVDRLQEEPKGVLQIAAVIGQRFSPSLARQVSELGDSFDRHLGELEKL 618 Query: 560 NLVDQVRFTAPVEYAFRHPLIRTVAYESQLK 590 L+ + + V Y F+H L++ Y S L+ Sbjct: 619 GLIFREQAEEQVLYRFKHALLQDAVYNSLLQ 649 >tr|Q89CC0|Q89CC0_BRAJA Tax_Id=375 SubName: Full=Bll7877 protein;[Bradyrhizobium japonicum] Length = 1018 Score = 211 bits (538), Expect = 2e-52 Identities = 168/595 (28%), Positives = 280/595 (47%), Gaps = 22/595 (3%) Query: 7 CVACGAELRSIAKFCDECGSPVVEAETP-AEYKQVTVLFADVVGSMDIAAAVGLERLREI 65 C AC + + +C +CG+ V P +E + VT+L ADV+ S + A + E Sbjct: 3 CFACQSAIDPDDSWCSKCGAAVRRRADPDSERRFVTILRADVIDSTGLVAELEPEEAVSR 62 Query: 66 MTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAA 125 + ++ G + ++GG V K GDG+ A+FGAP A ++HA AC AA+ + + RL Sbjct: 63 LEPALAAMRGAVRQFGGIVSKELGDGLAAVFGAPIADDNHAPLACHAAIELVRRVGRL-- 120 Query: 126 EVGDRDGVDLQLRVGLNSGQVIVGEIGSS-ALGYTAVGVQVGMAQRMESVAPPGVVMLSE 184 GD LQ+RVGL+SG V+ + S + Y G +A R+E+ A + +SE Sbjct: 121 --GDPG---LQVRVGLHSGHVVAYMVASEFSKVYEIGGAAQHLAARLEAAAEANQIYVSE 175 Query: 185 STARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEP---RQPTWFSESTLVGREWELA 241 + +L + + ++G + +P R++ ++ R S S V R E A Sbjct: 176 ACQKLADGHVRFESLGLKVLRGFNEPLPVYRVVGASDLSSWRVRRARSVSRFVDRTTERA 235 Query: 242 TLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFD 301 L +RS R +V+ L+G AGIGK+RL E Q K + C + V F Sbjct: 236 LLGRAAERSSASRQTVL-LIGDAGIGKSRLAHEFAQELKADGWRLIDAECSPNLQGVPFS 294 Query: 302 VVAQLVRAVAQISGLDDRSARARVREQIPDADTQXXXXXXXXXGIADPAVEXXXXXXXXX 361 + +++ ++++++ D S +R+++ A Q + DP Sbjct: 295 ALKRIILSISEVTARDSDSL-VDIRQEL-QAIHQLAIDSILDIPVEDPRWSELEPYARAR 352 Query: 362 XXXXXXXINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYH 421 V LA + V ++ED+HWID SD+++A +A + M +T RP Sbjct: 353 AISDASCAIVQGLAFQQRTVLLIEDLHWIDRASDAVVAA-IASLQSPNLMVFLTSRPNGM 411 Query: 422 GALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRE 481 A++IA+ PL D ++A++LG + T + I A P F +E+ R Sbjct: 412 PEWIARCHAEVIAMRPLDDDSGLAMLADMLGPSATNTDLKNRIISHTANVPLFLEEVCRG 471 Query: 482 LAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGS 541 L + G L G+ G A + E+ +P ++Q IAAR+DR+S + +L AA +G R Sbjct: 472 LKDSGTLRGQWGDLALVRPIDELGIPTSIQGVIAARLDRISRQERSVLQIAAALGPRSSV 531 Query: 542 DLL---ASLGIDLSVD---ELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLK 590 +L A+L D+ D L A L+ ++ F+H ++R V YES ++ Sbjct: 532 MMLRNVAALPEDVFQDCLGALDRAELLVRIDSELEDSIEFQHEMVRQVTYESMVE 586 Database: Amellifera_nr Posted date: Jan 15, 2010 5:10 AM Number of letters in database: 3,808,957,724 Number of sequences in database: 11,153,314 Lambda K H 0.320 0.133 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11153314 Number of Hits to DB: 4,684,559,857 Number of extensions: 180982694 Number of successful extensions: 685218 Number of sequences better than 10.0: 4976 Number of HSP's gapped: 684810 Number of HSP's successfully gapped: 5980 Length of query: 732 Length of database: 3,808,957,724 Length adjustment: 145 Effective length of query: 587 Effective length of database: 2,191,727,194 Effective search space: 1286543862878 Effective search space used: 1286543862878 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 84 (37.0 bits)