BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= ML2419c (329 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,153,314 sequences; 3,808,957,724 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|P46723|HEM2_MYCLE Tax_Id=1769 (hemB)RecName: Full=Delta-amino... 622 e-176 tr|B8ZT68|B8ZT68_MYCLB Tax_Id=561304 (hemB)RecName: Full=Delta-a... 622 e-176 sp|O33357|HEM2_MYCTU Tax_Id=1773 (hemB)RecName: Full=Delta-amino... 548 e-154 tr|C6DT98|C6DT98_MYCTK Tax_Id=478434 RecName: Full=Delta-aminole... 548 e-154 tr|A5TZP2|A5TZP2_MYCTA Tax_Id=419947 (hemB)RecName: Full=Delta-a... 548 e-154 tr|A5WJM7|A5WJM7_MYCTF Tax_Id=336982 RecName: Full=Delta-aminole... 548 e-154 tr|A4KEJ8|A4KEJ8_MYCTU Tax_Id=395095 RecName: Full=Delta-aminole... 548 e-154 tr|A2VFJ7|A2VFJ7_MYCTU Tax_Id=348776 RecName: Full=Delta-aminole... 548 e-154 tr|Q7U1W0|Q7U1W0_MYCBO Tax_Id=1765 (hemB)RecName: Full=Delta-ami... 545 e-153 tr|C1AKJ2|C1AKJ2_MYCBT Tax_Id=561275 (hemB)RecName: Full=Delta-a... 545 e-153 tr|A1KFY8|A1KFY8_MYCBP Tax_Id=410289 (hemB)RecName: Full=Delta-a... 545 e-153 tr|B2HRJ4|B2HRJ4_MYCMM Tax_Id=216594 (hemB)RecName: Full=Delta-a... 543 e-153 tr|Q73SR8|Q73SR8_MYCPA Tax_Id=1770 (hemB)RecName: Full=Delta-ami... 542 e-152 tr|A0PW31|A0PW31_MYCUA Tax_Id=362242 (hemB)RecName: Full=Delta-a... 538 e-151 tr|A0QR20|A0QR20_MYCS2 Tax_Id=246196 (hemB)RecName: Full=Delta-a... 515 e-144 tr|A1T3D5|A1T3D5_MYCVP Tax_Id=350058 RecName: Full=Delta-aminole... 499 e-139 tr|Q1BE84|Q1BE84_MYCSS Tax_Id=164756 RecName: Full=Delta-aminole... 498 e-139 tr|A3PUA6|A3PUA6_MYCSJ Tax_Id=164757 RecName: Full=Delta-aminole... 498 e-139 tr|A1UAQ0|A1UAQ0_MYCSK Tax_Id=189918 RecName: Full=Delta-aminole... 498 e-139 tr|A0QLH8|A0QLH8_MYCA1 Tax_Id=243243 (hemB)RecName: Full=Delta-a... 488 e-136 tr|A4T350|A4T350_MYCGI Tax_Id=350054 RecName: Full=Delta-aminole... 484 e-135 tr|B1MHI3|B1MHI3_MYCA9 Tax_Id=561007 RecName: Full=Delta-aminole... 460 e-128 tr|C1AZ41|C1AZ41_RHOOB Tax_Id=632772 (hemB)RecName: Full=Delta-a... 458 e-127 tr|Q0SF29|Q0SF29_RHOSR Tax_Id=101510 RecName: Full=Delta-aminole... 457 e-127 tr|C0ZUV7|C0ZUV7_RHOE4 Tax_Id=234621 (hemB)RecName: Full=Delta-a... 453 e-125 tr|C3JK02|C3JK02_RHOER Tax_Id=596309 (hemB)RecName: Full=Delta-a... 450 e-125 tr|C7MT09|C7MT09_SACVD Tax_Id=471857 RecName: Full=Delta-aminole... 447 e-123 tr|Q5YP73|Q5YP73_NOCFA Tax_Id=37329 (hemB)RecName: Full=Delta-am... 444 e-123 tr|A4FPY1|A4FPY1_SACEN Tax_Id=405948 (hemB)RecName: Full=Delta-a... 436 e-120 tr|D0L4A3|D0L4A3_9ACTO Tax_Id=526226 SubName: Full=Porphobilinog... 433 e-119 tr|C2AL34|C2AL34_TSUPA Tax_Id=521096 RecName: Full=Delta-aminole... 432 e-119 tr|Q82E74|Q82E74_STRAW Tax_Id=33903 (hemB)RecName: Full=Delta-am... 422 e-116 sp|P54919|HEM2_STRCO Tax_Id=1902 (hemB)RecName: Full=Delta-amino... 421 e-116 tr|B1VT97|B1VT97_STRGG Tax_Id=455632 RecName: Full=Delta-aminole... 420 e-115 tr|B4V345|B4V345_9ACTO Tax_Id=465541 RecName: Full=Delta-aminole... 419 e-115 tr|B5GNL9|B5GNL9_STRCL Tax_Id=443255 RecName: Full=Delta-aminole... 417 e-115 tr|C6WNG0|C6WNG0_ACTMD Tax_Id=446462 RecName: Full=Delta-aminole... 416 e-114 tr|C9N6G4|C9N6G4_9ACTO Tax_Id=591167 SubName: Full=Porphobilinog... 413 e-113 tr|B8HBR4|B8HBR4_ARTCA Tax_Id=452863 RecName: Full=Delta-aminole... 412 e-113 tr|B5HKN3|B5HKN3_STRPR Tax_Id=457429 RecName: Full=Delta-aminole... 412 e-113 tr|B5GKE2|B5GKE2_9ACTO Tax_Id=465543 RecName: Full=Delta-aminole... 407 e-112 tr|C7MH06|C7MH06_BRAFD Tax_Id=446465 RecName: Full=Delta-aminole... 406 e-111 tr|A1R8A0|A1R8A0_ARTAT Tax_Id=290340 (hemB)RecName: Full=Delta-a... 406 e-111 tr|B5I6Y3|B5I6Y3_9ACTO Tax_Id=463191 RecName: Full=Delta-aminole... 405 e-111 tr|Q4JSX7|Q4JSX7_CORJK Tax_Id=306537 (hemB)RecName: Full=Delta-a... 405 e-111 tr|B2GL26|B2GL26_KOCRD Tax_Id=378753 (hemB)RecName: Full=Delta-a... 404 e-111 tr|A0JYM4|A0JYM4_ARTS2 Tax_Id=290399 RecName: Full=Delta-aminole... 404 e-111 tr|B1VEK0|B1VEK0_CORU7 Tax_Id=504474 RecName: Full=Delta-aminole... 403 e-110 tr|A8LZJ2|A8LZJ2_SALAI Tax_Id=391037 RecName: Full=Delta-aminole... 402 e-110 tr|A1SE04|A1SE04_NOCSJ Tax_Id=196162 RecName: Full=Delta-aminole... 402 e-110 >sp|P46723|HEM2_MYCLE Tax_Id=1769 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; Short=ALADH; Short=ALAD; EC=4.2.1.24; AltName: Full=Porphobilinogen synthase;[Mycobacterium leprae] Length = 329 Score = 622 bits (1604), Expect = e-176 Identities = 316/329 (96%), Positives = 317/329 (96%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +SVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT Sbjct: 1 MSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR LNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV Sbjct: 61 RDSLRRAAVAAVDAGVGGLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG Sbjct: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI Sbjct: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA Sbjct: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLTSIRRAGADIVFTYWAADVACWLS Sbjct: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 >tr|B8ZT68|B8ZT68_MYCLB Tax_Id=561304 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium leprae] Length = 329 Score = 622 bits (1604), Expect = e-176 Identities = 316/329 (96%), Positives = 317/329 (96%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +SVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT Sbjct: 1 MSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR LNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV Sbjct: 61 RDSLRRAAVAAVDAGVGGLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG Sbjct: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI Sbjct: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA Sbjct: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLTSIRRAGADIVFTYWAADVACWLS Sbjct: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 >sp|O33357|HEM2_MYCTU Tax_Id=1773 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; Short=ALADH; Short=ALAD; EC=4.2.1.24; AltName: Full=Porphobilinogen synthase;[Mycobacterium tuberculosis] Length = 329 Score = 548 bits (1412), Expect = e-154 Identities = 278/329 (84%), Positives = 294/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLDEGADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDEGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|C6DT98|C6DT98_MYCTK Tax_Id=478434 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium tuberculosis] Length = 329 Score = 548 bits (1412), Expect = e-154 Identities = 278/329 (84%), Positives = 294/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLDEGADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDEGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|A5TZP2|A5TZP2_MYCTA Tax_Id=419947 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium tuberculosis] Length = 329 Score = 548 bits (1412), Expect = e-154 Identities = 278/329 (84%), Positives = 294/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLDEGADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDEGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|A5WJM7|A5WJM7_MYCTF Tax_Id=336982 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium tuberculosis] Length = 329 Score = 548 bits (1412), Expect = e-154 Identities = 278/329 (84%), Positives = 294/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLDEGADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDEGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|A4KEJ8|A4KEJ8_MYCTU Tax_Id=395095 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium tuberculosis str. Haarlem] Length = 329 Score = 548 bits (1412), Expect = e-154 Identities = 278/329 (84%), Positives = 294/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLDEGADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDEGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|A2VFJ7|A2VFJ7_MYCTU Tax_Id=348776 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium tuberculosis C] Length = 329 Score = 548 bits (1412), Expect = e-154 Identities = 278/329 (84%), Positives = 294/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLDEGADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDEGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|Q7U1W0|Q7U1W0_MYCBO Tax_Id=1765 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium bovis] Length = 329 Score = 545 bits (1405), Expect = e-153 Identities = 277/329 (84%), Positives = 293/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLD GADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDGGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|C1AKJ2|C1AKJ2_MYCBT Tax_Id=561275 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium bovis] Length = 329 Score = 545 bits (1405), Expect = e-153 Identities = 277/329 (84%), Positives = 293/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLD GADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDGGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|A1KFY8|A1KFY8_MYCBP Tax_Id=410289 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium bovis] Length = 329 Score = 545 bits (1405), Expect = e-153 Identities = 277/329 (84%), Positives = 293/329 (89%) Query: 1 VSVSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHT 60 +S+S YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGIDE RPI SMPGVVQHT Sbjct: 1 MSMSSYPRQRPRRLRSTVAMRRLVAQTSLEPRHLVLPMFVADGIDEPRPITSMPGVVQHT 60 Query: 61 RDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATV 120 RDSLRR L LFGVPRDQDKD GSAG+DPDGILNVALRDLA+DLG+ATV Sbjct: 61 RDSLRRAAAAAVAAGVGGLMLFGVPRDQDKDGVGSAGIDPDGILNVALRDLAKDLGEATV 120 Query: 121 LMADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIG 180 LMADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQAESGA+VVGPSGMMDGQ+ Sbjct: 121 LMADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAESGAHVVGPSGMMDGQVA 180 Query: 181 ALRDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREI 240 A+RDGLD+AGY DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQEPGNA EALREI Sbjct: 181 AIRDGLDAAGYIDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQEPGNAAEALREI 240 Query: 241 KLDLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAA 300 +LDLD GADI+M+KPA GYLDVVA AA VSPVPVAAYQVSGEYAMI AAAANNWIDERAA Sbjct: 241 ELDLDGGADIVMVKPAMGYLDVVAAAADVSPVPVAAYQVSGEYAMIRAAAANNWIDERAA 300 Query: 301 VLESLTSIRRAGADIVFTYWAADVACWLS 329 VLESLT IRRAGADIV TYWA D A WL+ Sbjct: 301 VLESLTGIRRAGADIVLTYWAVDAAGWLT 329 >tr|B2HRJ4|B2HRJ4_MYCMM Tax_Id=216594 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium marinum] Length = 327 Score = 543 bits (1400), Expect = e-153 Identities = 272/327 (83%), Positives = 291/327 (88%) Query: 3 VSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRD 62 + YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGI+E RPIASMPGV+QHTRD Sbjct: 1 MGAYPRQRPRRLRSTAAMRRLVAQTSLEPRHLVLPMFVADGIEEPRPIASMPGVMQHTRD 60 Query: 63 SLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLM 122 SLR L LFGVPRD KD GSAG DPDGILN ALRDLA+DLGDATVLM Sbjct: 61 SLRSAAADAVSAGVGGLMLFGVPRDTSKDPVGSAGTDPDGILNAALRDLAKDLGDATVLM 120 Query: 123 ADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGAL 182 ADTCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQA++GA+VVGPSGMMDGQ+GA+ Sbjct: 121 ADTCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAQAGAHVVGPSGMMDGQVGAI 180 Query: 183 RDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKL 242 RDGLD AG+ADV ILAYAAKF+SAFYGPFREAVSCSLSGDRRTYQQEPGN REALRE++L Sbjct: 181 RDGLDEAGHADVVILAYAAKFASAFYGPFREAVSCSLSGDRRTYQQEPGNMREALREVEL 240 Query: 243 DLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVL 302 DLDEGADI+MIKPA GYLDVVA AA +SPVPVAAYQVSGEYAMICAAAAN+WID+RAA L Sbjct: 241 DLDEGADIVMIKPALGYLDVVAAAADISPVPVAAYQVSGEYAMICAAAANSWIDQRAAAL 300 Query: 303 ESLTSIRRAGADIVFTYWAADVACWLS 329 ESLTSIRRAGADIV TYWAAD A WLS Sbjct: 301 ESLTSIRRAGADIVLTYWAADAASWLS 327 >tr|Q73SR8|Q73SR8_MYCPA Tax_Id=1770 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium paratuberculosis] Length = 326 Score = 542 bits (1396), Expect = e-152 Identities = 274/324 (84%), Positives = 290/324 (89%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 YPR RPRRLRSTPA+RRLVAQTSLEPR+LVLPMFVADGIDE RPIASMP VVQHTRDSLR Sbjct: 3 YPRQRPRRLRSTPALRRLVAQTSLEPRHLVLPMFVADGIDEPRPIASMPKVVQHTRDSLR 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 L LFGVPRD+DKD GSAG DPDGILNVALRDLA+DLGDATVLMADT Sbjct: 63 AAAASAVAAGVGGLMLFGVPRDEDKDPIGSAGTDPDGILNVALRDLAKDLGDATVLMADT 122 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLD +GRVDNDATVARYV LAVAQAESGA+VVGPSGMMDGQ+GA+RDG Sbjct: 123 CLDEFTDHGHCGVLDDRGRVDNDATVARYVNLAVAQAESGAHVVGPSGMMDGQVGAIRDG 182 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+AG+ DV ILAYAAKF+SAFYGPFREAVS SLSGDRRTYQQE GN+REALREI+LDLD Sbjct: 183 LDAAGFTDVVILAYAAKFASAFYGPFREAVSSSLSGDRRTYQQETGNSREALREIRLDLD 242 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGADI+M+KPA YLDVVA AA VSPVPVAAYQVSGEYAMICAAAANNWIDERAA LESL Sbjct: 243 EGADIVMVKPAMSYLDVVAAAAEVSPVPVAAYQVSGEYAMICAAAANNWIDERAAALESL 302 Query: 306 TSIRRAGADIVFTYWAADVACWLS 329 TSIRRAGADIV +YWAAD A WLS Sbjct: 303 TSIRRAGADIVLSYWAADAAGWLS 326 >tr|A0PW31|A0PW31_MYCUA Tax_Id=362242 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium ulcerans] Length = 327 Score = 538 bits (1387), Expect = e-151 Identities = 271/327 (82%), Positives = 290/327 (88%) Query: 3 VSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRD 62 + YPR RPRRLRST AMRRLVAQTSLEPR+LVLPMFVADGI+E RPIASMPGV+QHTRD Sbjct: 1 MGAYPRQRPRRLRSTAAMRRLVAQTSLEPRHLVLPMFVADGIEEPRPIASMPGVMQHTRD 60 Query: 63 SLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLM 122 SLR L LFGVPRD KD GSAG DPDGILN ALRDLA+DLGDATVLM Sbjct: 61 SLRSAAADAVSAGVGGLMLFGVPRDTSKDPVGSAGTDPDGILNAALRDLAKDLGDATVLM 120 Query: 123 ADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGAL 182 A+TCLDEFTDHGHCGVLD +GRVDNDATVARYVELAVAQA++GA+VVGPSGMMDGQ+GA+ Sbjct: 121 AETCLDEFTDHGHCGVLDDRGRVDNDATVARYVELAVAQAQAGAHVVGPSGMMDGQVGAI 180 Query: 183 RDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKL 242 RDGLD AGYADV ILAYAAKF+SAFYGPFREAVSCSLSGDRRTYQQEPGN REALRE++L Sbjct: 181 RDGLDEAGYADVVILAYAAKFASAFYGPFREAVSCSLSGDRRTYQQEPGNMREALREVEL 240 Query: 243 DLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVL 302 DLDEGADI+MIKPA GYLDVVA AA +SPVPVAAYQVSGEYAMICAAAAN+ ID+RAA L Sbjct: 241 DLDEGADIVMIKPALGYLDVVAAAADISPVPVAAYQVSGEYAMICAAAANSRIDQRAAAL 300 Query: 303 ESLTSIRRAGADIVFTYWAADVACWLS 329 ESLTSIRRAGADIV TYWAAD A WLS Sbjct: 301 ESLTSIRRAGADIVLTYWAADAASWLS 327 >tr|A0QR20|A0QR20_MYCS2 Tax_Id=246196 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium smegmatis] Length = 326 Score = 515 bits (1326), Expect = e-144 Identities = 254/324 (78%), Positives = 284/324 (87%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +PRHRPRRLR+TPAMRRLVAQTSLEPR+L+LPMFVADGIDE RPI SMPGVVQHTRDSLR Sbjct: 3 FPRHRPRRLRTTPAMRRLVAQTSLEPRHLILPMFVADGIDEPRPINSMPGVVQHTRDSLR 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 R L LFGVP D+DKDATGS GVDPDGILNVALRDLA+DLGD+TVLMADT Sbjct: 63 RAAADAVAAGVGGLMLFGVPLDEDKDATGSVGVDPDGILNVALRDLAKDLGDSTVLMADT 122 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLD GRVDNDAT RYVELAVAQA+SGA+VVGPSGMMDGQ+ A+RDG Sbjct: 123 CLDEFTDHGHCGVLDAHGRVDNDATNLRYVELAVAQADSGAHVVGPSGMMDGQVAAIRDG 182 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+AG+ DVAILAY+AKF+SAFYGPFREAVS SL+GDRRTYQQ+ GN REA+REI+LD+D Sbjct: 183 LDAAGHTDVAILAYSAKFASAFYGPFREAVSSSLTGDRRTYQQDAGNIREAVREIELDID 242 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLDVV AA +SPVPVAAYQ+SGEY+MI AAAAN WID + A LESL Sbjct: 243 EGADMVMVKPAMSYLDVVRAAAEISPVPVAAYQISGEYSMISAAAANGWIDLQTAALESL 302 Query: 306 TSIRRAGADIVFTYWAADVACWLS 329 IRRAGAD++ TYWAADVA WL+ Sbjct: 303 VGIRRAGADLILTYWAADVAGWLA 326 >tr|A1T3D5|A1T3D5_MYCVP Tax_Id=350058 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium vanbaalenii] Length = 326 Score = 499 bits (1286), Expect = e-139 Identities = 250/324 (77%), Positives = 273/324 (84%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +PRHRPRRLR+TPAMRRLVAQTSLEPR+LVLPMFVADGI+E R I SMPGVVQHTRDSLR Sbjct: 3 FPRHRPRRLRTTPAMRRLVAQTSLEPRHLVLPMFVADGIEEPRDITSMPGVVQHTRDSLR 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 R L LFGVPRD+DKD TGS GVDPDGILN ALRDLA+DLGD+TVLMADT Sbjct: 63 RAAADAVAAGVGGLMLFGVPRDEDKDPTGSVGVDPDGILNRALRDLAKDLGDSTVLMADT 122 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLD GRVDND T RYVELAVAQA SGA++VGPSGMMDGQ+ A+RDG Sbjct: 123 CLDEFTDHGHCGVLDPTGRVDNDLTNRRYVELAVAQANSGAHMVGPSGMMDGQVAAIRDG 182 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+AGY++ AILAYAAKF+S FYGPFREAV SL GDRRTYQQ+PGNAREAL EI+LD+D Sbjct: 183 LDAAGYSETAILAYAAKFASGFYGPFREAVGSSLQGDRRTYQQDPGNAREALHEIQLDID 242 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGADI+M+KPA YLDVV AA +SPVPVAAYQVSGEY+MI AA WID A VLESL Sbjct: 243 EGADIVMVKPAMAYLDVVRAAAEISPVPVAAYQVSGEYSMIAAAGEKGWIDLPAVVLESL 302 Query: 306 TSIRRAGADIVFTYWAADVACWLS 329 IRRAGADI +YWA DVA WLS Sbjct: 303 EGIRRAGADIALSYWAVDVAHWLS 326 >tr|Q1BE84|Q1BE84_MYCSS Tax_Id=164756 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium sp.] Length = 323 Score = 498 bits (1281), Expect = e-139 Identities = 249/321 (77%), Positives = 277/321 (86%) Query: 8 RHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRRX 67 R RPRRLRSTPAMRRLVA+TSLEPR+LVLPMFVADGIDE RPI+SMPGVVQHTRDSLRR Sbjct: 2 RQRPRRLRSTPAMRRLVAETSLEPRHLVLPMFVADGIDEPRPISSMPGVVQHTRDSLRRA 61 Query: 68 XXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTCL 127 L LFGVPRD+DKD GS G+DP+GILNVALRDLA+DLG+ TV+MADTCL Sbjct: 62 AADAVAAGVGGLMLFGVPRDEDKDPRGSIGMDPEGILNVALRDLAKDLGEDTVIMADTCL 121 Query: 128 DEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGLD 187 DEFTDHGHCGVLD +GRVDNDAT +YV+LAVAQA+SGA+VV PSGMMDGQ+ A+RDGLD Sbjct: 122 DEFTDHGHCGVLDDRGRVDNDATNQQYVKLAVAQAQSGAHVVAPSGMMDGQVAAIRDGLD 181 Query: 188 SAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDEG 247 AG+ DVAILAYAAKF+SAFYGPFREAV SL GDRRTYQQ+ GNAREALREI+LDL EG Sbjct: 182 GAGHTDVAILAYAAKFASAFYGPFREAVGSSLQGDRRTYQQDSGNAREALREIELDLAEG 241 Query: 248 ADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLTS 307 AD++M+KPA YLDVV A +SPVPVAAYQ+SGEYAMI AAAAN WID +A+ LE+LT Sbjct: 242 ADMVMVKPAMSYLDVVRACADISPVPVAAYQISGEYAMISAAAANGWIDLQASALEALTG 301 Query: 308 IRRAGADIVFTYWAADVACWL 328 IRRAGADIV TYWAADVA WL Sbjct: 302 IRRAGADIVLTYWAADVAGWL 322 >tr|A3PUA6|A3PUA6_MYCSJ Tax_Id=164757 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium sp.] Length = 323 Score = 498 bits (1281), Expect = e-139 Identities = 249/321 (77%), Positives = 277/321 (86%) Query: 8 RHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRRX 67 R RPRRLRSTPAMRRLVA+TSLEPR+LVLPMFVADGIDE RPI+SMPGVVQHTRDSLRR Sbjct: 2 RQRPRRLRSTPAMRRLVAETSLEPRHLVLPMFVADGIDEPRPISSMPGVVQHTRDSLRRA 61 Query: 68 XXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTCL 127 L LFGVPRD+DKD GS G+DP+GILNVALRDLA+DLG+ TV+MADTCL Sbjct: 62 AADAVAAGVGGLMLFGVPRDEDKDPRGSIGMDPEGILNVALRDLAKDLGEDTVIMADTCL 121 Query: 128 DEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGLD 187 DEFTDHGHCGVLD +GRVDNDAT +YV+LAVAQA+SGA+VV PSGMMDGQ+ A+RDGLD Sbjct: 122 DEFTDHGHCGVLDDRGRVDNDATNQQYVKLAVAQAQSGAHVVAPSGMMDGQVAAIRDGLD 181 Query: 188 SAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDEG 247 AG+ DVAILAYAAKF+SAFYGPFREAV SL GDRRTYQQ+ GNAREALREI+LDL EG Sbjct: 182 GAGHTDVAILAYAAKFASAFYGPFREAVGSSLQGDRRTYQQDSGNAREALREIELDLAEG 241 Query: 248 ADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLTS 307 AD++M+KPA YLDVV A +SPVPVAAYQ+SGEYAMI AAAAN WID +A+ LE+LT Sbjct: 242 ADMVMVKPAMSYLDVVRACADISPVPVAAYQISGEYAMISAAAANGWIDLQASALEALTG 301 Query: 308 IRRAGADIVFTYWAADVACWL 328 IRRAGADIV TYWAADVA WL Sbjct: 302 IRRAGADIVLTYWAADVAGWL 322 >tr|A1UAQ0|A1UAQ0_MYCSK Tax_Id=189918 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium sp.] Length = 323 Score = 498 bits (1281), Expect = e-139 Identities = 249/321 (77%), Positives = 277/321 (86%) Query: 8 RHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRRX 67 R RPRRLRSTPAMRRLVA+TSLEPR+LVLPMFVADGIDE RPI+SMPGVVQHTRDSLRR Sbjct: 2 RQRPRRLRSTPAMRRLVAETSLEPRHLVLPMFVADGIDEPRPISSMPGVVQHTRDSLRRA 61 Query: 68 XXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTCL 127 L LFGVPRD+DKD GS G+DP+GILNVALRDLA+DLG+ TV+MADTCL Sbjct: 62 AADAVAAGVGGLMLFGVPRDEDKDPRGSIGMDPEGILNVALRDLAKDLGEDTVIMADTCL 121 Query: 128 DEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGLD 187 DEFTDHGHCGVLD +GRVDNDAT +YV+LAVAQA+SGA+VV PSGMMDGQ+ A+RDGLD Sbjct: 122 DEFTDHGHCGVLDDRGRVDNDATNQQYVKLAVAQAQSGAHVVAPSGMMDGQVAAIRDGLD 181 Query: 188 SAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDEG 247 AG+ DVAILAYAAKF+SAFYGPFREAV SL GDRRTYQQ+ GNAREALREI+LDL EG Sbjct: 182 GAGHTDVAILAYAAKFASAFYGPFREAVGSSLQGDRRTYQQDSGNAREALREIELDLAEG 241 Query: 248 ADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLTS 307 AD++M+KPA YLDVV A +SPVPVAAYQ+SGEYAMI AAAAN WID +A+ LE+LT Sbjct: 242 ADMVMVKPAMSYLDVVRACADISPVPVAAYQISGEYAMISAAAANGWIDLQASALEALTG 301 Query: 308 IRRAGADIVFTYWAADVACWL 328 IRRAGADIV TYWAADVA WL Sbjct: 302 IRRAGADIVLTYWAADVAGWL 322 >tr|A0QLH8|A0QLH8_MYCA1 Tax_Id=243243 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium avium] Length = 295 Score = 488 bits (1255), Expect = e-136 Identities = 246/295 (83%), Positives = 262/295 (88%) Query: 35 VLPMFVADGIDELRPIASMPGVVQHTRDSLRRXXXXXXXXXXXXLNLFGVPRDQDKDATG 94 +LPMFVADGIDE RPIASMP VVQHTRDSLR L LFGVPRD++KD G Sbjct: 1 MLPMFVADGIDEPRPIASMPKVVQHTRDSLRAAAASAVAAGVGGLMLFGVPRDEEKDPIG 60 Query: 95 SAGVDPDGILNVALRDLAEDLGDATVLMADTCLDEFTDHGHCGVLDGQGRVDNDATVARY 154 SAG DPDGILNVALRDLA+DLGDATVLMADTCLDEFTDHGHCGVLD +GRVDNDATVARY Sbjct: 61 SAGTDPDGILNVALRDLAKDLGDATVLMADTCLDEFTDHGHCGVLDDRGRVDNDATVARY 120 Query: 155 VELAVAQAESGANVVGPSGMMDGQIGALRDGLDSAGYADVAILAYAAKFSSAFYGPFREA 214 V LAVAQAESGA+VVGPSGMMDGQ+GA+RDGLD+AG+ DV ILAYAAKF+SAFYGPFREA Sbjct: 121 VNLAVAQAESGAHVVGPSGMMDGQVGAIRDGLDAAGFTDVVILAYAAKFASAFYGPFREA 180 Query: 215 VSCSLSGDRRTYQQEPGNAREALREIKLDLDEGADIIMIKPASGYLDVVATAAGVSPVPV 274 VS SLSGDRRTYQQE GN+REALREI+LDLDEGADI+M+KPA YLDVVA AA VSPVPV Sbjct: 181 VSSSLSGDRRTYQQETGNSREALREIRLDLDEGADIVMVKPAMSYLDVVAAAAEVSPVPV 240 Query: 275 AAYQVSGEYAMICAAAANNWIDERAAVLESLTSIRRAGADIVFTYWAADVACWLS 329 AAYQVSGEYAMICAAAANNWIDERAA LESLTSIRRAGADIV +YWAAD A WLS Sbjct: 241 AAYQVSGEYAMICAAAANNWIDERAAALESLTSIRRAGADIVLSYWAADAAGWLS 295 >tr|A4T350|A4T350_MYCGI Tax_Id=350054 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium gilvum] Length = 326 Score = 484 bits (1246), Expect = e-135 Identities = 240/325 (73%), Positives = 266/325 (81%) Query: 5 GYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSL 64 G+PRHRPRRLR+TPAMRRLV++TSLEPR+LVLPMFVADG+DE R IASMPGVVQHTR+SL Sbjct: 2 GFPRHRPRRLRTTPAMRRLVSETSLEPRHLVLPMFVADGLDEPRDIASMPGVVQHTRESL 61 Query: 65 RRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMAD 124 RR L LFGVPRD+DKDATGS GVDPDGILN ALRDL DLGD TVLMAD Sbjct: 62 RRAAAEAVEAGVGGLMLFGVPRDEDKDATGSIGVDPDGILNRALRDLTRDLGDDTVLMAD 121 Query: 125 TCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRD 184 TCLDEFTDHGHCGV+D GRVDND T RYVELAVAQA SGA VV PSGMMDGQ+ A+RD Sbjct: 122 TCLDEFTDHGHCGVVDPTGRVDNDLTNRRYVELAVAQANSGAQVVSPSGMMDGQVAAIRD 181 Query: 185 GLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDL 244 GLD AGY AILAY+AKF+S FYGPFREAV SL GDRRTYQQ+PGN REAL E++LD+ Sbjct: 182 GLDVAGYTHTAILAYSAKFASGFYGPFREAVGSSLEGDRRTYQQDPGNGREALHEVRLDI 241 Query: 245 DEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLES 304 +EGADI+M+KPA YLDVV A + P+P+AAYQVSGEY+MI AAA WID VLES Sbjct: 242 EEGADIVMVKPAMSYLDVVRATAEICPLPLAAYQVSGEYSMIAAAAEKGWIDLPTVVLES 301 Query: 305 LTSIRRAGADIVFTYWAADVACWLS 329 L IRRAGADIV +YWA DVA WL+ Sbjct: 302 LVGIRRAGADIVLSYWAVDVARWLT 326 >tr|B1MHI3|B1MHI3_MYCA9 Tax_Id=561007 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Mycobacterium abscessus] Length = 327 Score = 460 bits (1184), Expect = e-128 Identities = 229/324 (70%), Positives = 267/324 (82%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TPA+RRLVA+T+L PR LVLPMFVADG+ E + I+S+PGVVQH+ +SLR Sbjct: 3 FPYQRPRRLRATPAIRRLVAETTLAPRQLVLPMFVADGLTEPKAISSLPGVVQHSTESLR 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 R L LFGVP+++DKDATGSAG+ DGILN AL L+ DLGDATVLMADT Sbjct: 63 RAAEDAVKAGVGGLMLFGVPQEKDKDATGSAGLCADGILNRALSVLSADLGDATVLMADT 122 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLD GRVDNDAT+ +YV +AVAQA SGA VVGPSGMMDGQ+ A+R G Sbjct: 123 CLDEFTDHGHCGVLDAAGRVDNDATLTQYVHMAVAQANSGARVVGPSGMMDGQVAAIRAG 182 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+AG++DV I+AY AK++SAF+GPFREAV SL GDRRTYQQ+ N REALRE++LD+ Sbjct: 183 LDAAGHSDVIIMAYTAKYASAFFGPFREAVGSSLRGDRRTYQQDVANGREALRELELDVQ 242 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGADI+M+KPA YLDV+ A VSPVPVAAYQVSGEYAMICAAA NNWID +A LE+L Sbjct: 243 EGADIVMVKPAMAYLDVLRQVADVSPVPVAAYQVSGEYAMICAAAQNNWIDLQAMALETL 302 Query: 306 TSIRRAGADIVFTYWAADVACWLS 329 TSIRRAGADIV TYWAA+ A WLS Sbjct: 303 TSIRRAGADIVLTYWAAEAAGWLS 326 >tr|C1AZ41|C1AZ41_RHOOB Tax_Id=632772 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Rhodococcus opacus] Length = 326 Score = 458 bits (1179), Expect = e-127 Identities = 226/326 (69%), Positives = 262/326 (80%) Query: 3 VSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRD 62 +S +P HRPRRLR TPA+RRLVA+TSLEPR+LVLPMFVADGIDE R I+SMPGV QHT D Sbjct: 1 MSLFPTHRPRRLRRTPALRRLVAETSLEPRHLVLPMFVADGIDEPREISSMPGVFQHTPD 60 Query: 63 SLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLM 122 SLRR L LFGVPR DKDA GS DPDGILN LR LA+++GDATV+M Sbjct: 61 SLRRAATEAAEAGLGGLMLFGVPRPDDKDAEGSGASDPDGILNRGLRWLADEVGDATVIM 120 Query: 123 ADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGAL 182 ADTCLDEFTDHGHCGVLD G VDND T+ RYV++AVAQAE+GA+++GPSGMMDGQ+GA+ Sbjct: 121 ADTCLDEFTDHGHCGVLDANGAVDNDLTLQRYVDMAVAQAEAGAHLLGPSGMMDGQVGAI 180 Query: 183 RDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKL 242 R LD AGY DV LAY+AK++SAFYGPFREAV SL GDRRTYQQ+ N RE+LRE+ L Sbjct: 181 RKALDGAGYTDVGQLAYSAKYASAFYGPFREAVGSSLQGDRRTYQQDSANRRESLREVDL 240 Query: 243 DLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVL 302 D+DEGAD++M+KPA YLD++ A S VPVAAYQ+SGEY+MI AAA N WID AA+L Sbjct: 241 DVDEGADMVMVKPAMSYLDILRETADRSQVPVAAYQISGEYSMITAAAQNGWIDRDAAIL 300 Query: 303 ESLTSIRRAGADIVFTYWAADVACWL 328 ESLTSIRRAGAD+V TYWA + A WL Sbjct: 301 ESLTSIRRAGADVVLTYWATEAAGWL 326 >tr|Q0SF29|Q0SF29_RHOSR Tax_Id=101510 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Rhodococcus sp.] Length = 343 Score = 457 bits (1177), Expect = e-127 Identities = 227/326 (69%), Positives = 261/326 (80%) Query: 3 VSGYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRD 62 +S +P HRPRRLR TPA+RRLVA+TSLEPR+LVLPMFVADGIDE R I+SMPGV QHT D Sbjct: 18 MSLFPTHRPRRLRRTPALRRLVAETSLEPRHLVLPMFVADGIDEPREISSMPGVFQHTPD 77 Query: 63 SLRRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLM 122 SLRR L LFGVPR DKDA GS DPDGILN LR LA+++GDATV+M Sbjct: 78 SLRRAATEAVEAGLGGLMLFGVPRPDDKDAEGSGASDPDGILNRGLRWLADEVGDATVIM 137 Query: 123 ADTCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGAL 182 ADTCLDEFTDHGHCGVLD G VDND T+ RYVE+AVAQAE+GA+++GPSGMMDGQ+ A+ Sbjct: 138 ADTCLDEFTDHGHCGVLDESGAVDNDLTLQRYVEMAVAQAEAGAHLLGPSGMMDGQVAAI 197 Query: 183 RDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKL 242 R LD A Y DV LAY+AK++SAFYGPFREAV SL GDRRTYQQ+ N RE+LRE+ L Sbjct: 198 RKALDDADYTDVGQLAYSAKYASAFYGPFREAVGSSLQGDRRTYQQDSANRRESLREVDL 257 Query: 243 DLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVL 302 D+DEGAD++M+KPA YLDV+ A SPVPVAAYQ+SGEY+MI AAA N WID AA+L Sbjct: 258 DIDEGADMVMVKPAMSYLDVLRETADRSPVPVAAYQISGEYSMITAAAQNGWIDRDAAIL 317 Query: 303 ESLTSIRRAGADIVFTYWAADVACWL 328 ESLTSIRRAGAD+V TYWA + A WL Sbjct: 318 ESLTSIRRAGADVVLTYWATEAAGWL 343 >tr|C0ZUV7|C0ZUV7_RHOE4 Tax_Id=234621 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Rhodococcus erythropolis] Length = 324 Score = 453 bits (1166), Expect = e-125 Identities = 222/323 (68%), Positives = 262/323 (81%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P HRPRRLR TPA+RRLVA+TSLEPR+LVLPMFVADGID R I+SMPGV QHT DSLR Sbjct: 2 FPTHRPRRLRRTPALRRLVAETSLEPRHLVLPMFVADGIDTPREISSMPGVFQHTLDSLR 61 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 L LFGVP+ +DKD GS DPDGILNV LR LAE+LGD+TV+MADT Sbjct: 62 SAAVEAVEAGVGGLMLFGVPKAEDKDPQGSGASDPDGILNVGLRALAEELGDSTVIMADT 121 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVL+ G VDNDAT+ RYVE+A+AQAESGA+++GPSGMMDGQ+ A+R Sbjct: 122 CLDEFTDHGHCGVLNATGAVDNDATLIRYVEMALAQAESGAHLLGPSGMMDGQVAAIRGA 181 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD++GY +V LAYAAK++SAFYGPFREAV SL GDRRTYQQ+ N RE++RE+ LD+ Sbjct: 182 LDASGYVEVGQLAYAAKYASAFYGPFREAVGSSLQGDRRTYQQDGANRRESMREVDLDVA 241 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++ A SPVPVAAYQ+SGEY+MI AAA N WID AA+LESL Sbjct: 242 EGADMVMVKPAMSYLDILRETADRSPVPVAAYQISGEYSMITAAAQNGWIDRDAAILESL 301 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 TSIRRAGAD+V TYWA++VA WL Sbjct: 302 TSIRRAGADVVLTYWASEVAGWL 324 >tr|C3JK02|C3JK02_RHOER Tax_Id=596309 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Rhodococcus erythropolis SK121] Length = 344 Score = 450 bits (1158), Expect = e-125 Identities = 221/323 (68%), Positives = 260/323 (80%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P HRPRRLR TPA+RRLVA+TSLEPR+LVLPMFVADGID R I+SMPGV QHT DSLR Sbjct: 22 FPTHRPRRLRRTPALRRLVAETSLEPRHLVLPMFVADGIDAPREISSMPGVFQHTLDSLR 81 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 L LFGVP+ +DKD GS DPDGILNV LR LA++LGD+TV+MADT Sbjct: 82 SAAVEAVEAGVGGLMLFGVPKAEDKDPQGSGASDPDGILNVGLRALADELGDSTVIMADT 141 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVL G VDNDAT+ RYVE+A+AQAESGA+++GPSGMMDGQ+ A+R Sbjct: 142 CLDEFTDHGHCGVLTAGGAVDNDATLIRYVEMALAQAESGAHLLGPSGMMDGQVAAIRGA 201 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD++GY DV LAYAAK++SAFYGPFREAV SL GDRRTYQQ+ N RE++RE+ LD+ Sbjct: 202 LDASGYVDVGQLAYAAKYASAFYGPFREAVGSSLQGDRRTYQQDGANRRESMREVDLDVA 261 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++ A SPVPVAAYQ+SGEY+MI AAA N WID AA+LESL Sbjct: 262 EGADMVMVKPAMSYLDILRETADRSPVPVAAYQISGEYSMITAAAQNGWIDRDAAILESL 321 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 SIRRAGAD+V TYWA++VA WL Sbjct: 322 ISIRRAGADVVLTYWASEVAGWL 344 >tr|C7MT09|C7MT09_SACVD Tax_Id=471857 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Saccharomonospora viridis] Length = 323 Score = 447 bits (1149), Expect = e-123 Identities = 219/323 (67%), Positives = 255/323 (78%), Gaps = 2/323 (0%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P HRPRRLR+T AMRRLV++T+L PR L+LP+FVA+ E RPI SMPGVVQHTRD+LR Sbjct: 2 FPEHRPRRLRTTAAMRRLVSETTLRPRQLILPLFVAEDAREPRPIGSMPGVVQHTRDTLR 61 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 R L LFGVP + +DA G D DGILNVALRDL +LGDATVLMADT Sbjct: 62 RAAVEAVEAGVGGLMLFGVPAE--RDAVGGGATDADGILNVALRDLRSELGDATVLMADT 119 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLD G VDNDAT+ RY E+A+AQAE+GA+++GPSGMMDGQ+G +R Sbjct: 120 CLDEFTDHGHCGVLDESGAVDNDATLERYAEMALAQAEAGAHMLGPSGMMDGQVGVIRRA 179 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD AGY D ILAY+AK++SAFYGPFREAV L+GDR TYQQ+PGNAREALREI+LD+ Sbjct: 180 LDDAGYTDTGILAYSAKYASAFYGPFREAVDSQLTGDRNTYQQDPGNAREALREIELDIA 239 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD +M+KPA YLDVV AA VSPVPVAAY +SGEY+MI AAAN WID +LE L Sbjct: 240 EGADAVMVKPALAYLDVVKAAAEVSPVPVAAYNISGEYSMIEGAAANGWIDRERTILEVL 299 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 TSIRRAGAD++ TYWAA+ A WL Sbjct: 300 TSIRRAGADLILTYWAAEAAAWL 322 >tr|Q5YP73|Q5YP73_NOCFA Tax_Id=37329 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Nocardia farcinica] Length = 325 Score = 444 bits (1143), Expect = e-123 Identities = 220/320 (68%), Positives = 255/320 (79%) Query: 10 RPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRRXXX 69 RPRRLR TPA+RRLVA+T++EPR+LVLPMFVADG+DE R I SMPGV QH+ DSLR+ Sbjct: 6 RPRRLRRTPALRRLVAETTVEPRHLVLPMFVADGLDEPREIGSMPGVQQHSMDSLRKAAT 65 Query: 70 XXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTCLDE 129 L LFGVPR +DKD GS DPDGILN LR LAE++GDATV+MADTCLDE Sbjct: 66 EAVSAGVGGLMLFGVPRPEDKDPAGSQASDPDGILNRGLRALAEEVGDATVIMADTCLDE 125 Query: 130 FTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGLDSA 189 FTDHGHCGVL G VDNDAT+ RYV++A+AQAE+GA+++G SGMMDGQ+GA+R GLD+ Sbjct: 126 FTDHGHCGVLAADGHVDNDATLHRYVDMALAQAEAGADLLGTSGMMDGQVGAIRRGLDAV 185 Query: 190 GYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDEGAD 249 G D ILAYAAK+SSAFYGPFREAVS SL GDRRTYQQ+P N RE++ E+ LDL EGAD Sbjct: 186 GRTDTGILAYAAKYSSAFYGPFREAVSSSLQGDRRTYQQDPANRRESMHELDLDLAEGAD 245 Query: 250 IIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLTSIR 309 I+M+KPA YLD++ A SPVPVAAYQ+SGEY+MI AAA WID RAAVLESL IR Sbjct: 246 IVMVKPAMSYLDILREVADRSPVPVAAYQISGEYSMITAAAERGWIDRRAAVLESLVGIR 305 Query: 310 RAGADIVFTYWAADVACWLS 329 RAGADIV TYWA + A WLS Sbjct: 306 RAGADIVLTYWATEAAHWLS 325 >tr|A4FPY1|A4FPY1_SACEN Tax_Id=405948 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Saccharopolyspora erythraea] Length = 326 Score = 436 bits (1121), Expect = e-120 Identities = 214/323 (66%), Positives = 255/323 (78%), Gaps = 2/323 (0%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 YP HRPRRLR A+RRLV++TS+EPR+LVLPMFV +GI E PI SMPGVVQHTRDSLR Sbjct: 2 YPSHRPRRLRKNAAVRRLVSETSVEPRHLVLPMFVREGIAEPMPIPSMPGVVQHTRDSLR 61 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + L LFGVP + +DA GSAG DPDGILNVALRDL+ ++G TVLMAD Sbjct: 62 KAAVEAVSAGVGGLMLFGVPAE--RDAVGSAGTDPDGILNVALRDLSAEVGSDTVLMADL 119 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCG+LD +G VDND T+ Y E+AV QAESGA+VVGPSGMMDGQ+G +R+ Sbjct: 120 CLDEFTDHGHCGLLDSEGAVDNDRTLQVYGEMAVVQAESGADVVGPSGMMDGQVGVIRES 179 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+ G++D A+LAY+ K++SA++GPFR+AV L GDR+TYQQ+P N REALRE LDL Sbjct: 180 LDATGFSDTAVLAYSVKYASAYFGPFRDAVDSQLKGDRKTYQQDPANGREALREADLDLA 239 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLDV+ AGV+ VPVAAYQVSGEY+M+ AA AN W+D VLESL Sbjct: 240 EGADMVMVKPAMSYLDVLRDIAGVADVPVAAYQVSGEYSMVEAAVANGWLDRERTVLESL 299 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 TSIRRAGADIV TYWAA+ A WL Sbjct: 300 TSIRRAGADIVLTYWAAEAARWL 322 >tr|D0L4A3|D0L4A3_9ACTO Tax_Id=526226 SubName: Full=Porphobilinogen synthase; EC=4.2.1.24;[Gordonia bronchialis DSM 43247] Length = 325 Score = 433 bits (1113), Expect = e-119 Identities = 218/323 (67%), Positives = 252/323 (78%) Query: 7 PRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRR 66 P RPRRLRST A+RRLVA+T+L PR LVLPMFVADG+D R I+SMPGV+QHT DSLR+ Sbjct: 3 PVIRPRRLRSTAALRRLVAETTLAPRQLVLPMFVADGLDAPREISSMPGVLQHTVDSLRK 62 Query: 67 XXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTC 126 L LFGVP ++DKDATGS DG+LN ALR L +DLGD TVLMADTC Sbjct: 63 AADEAVRAGVGGLMLFGVPDEKDKDATGSGADADDGVLNRALRVLTDDLGDDTVLMADTC 122 Query: 127 LDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGL 186 LDEFTDHGHCGVLD GRVDNDAT+ RYV +++AQA SGA ++GPSGMMDGQ+ A+R L Sbjct: 123 LDEFTDHGHCGVLDAAGRVDNDATLDRYVSMSLAQARSGARLLGPSGMMDGQVAAIRTAL 182 Query: 187 DSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDE 246 D AG+ D ILAYAAK++SAFYGPFREAV SL GDRRTYQQ+ N EALRE++LDLDE Sbjct: 183 DDAGFTDTGILAYAAKYASAFYGPFREAVGSSLQGDRRTYQQDSANRIEALREVRLDLDE 242 Query: 247 GADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLT 306 GADI+M+KPA YLD+V A +S VPVAAYQ+SGEY+MI AAA WID AA+LESLT Sbjct: 243 GADIVMVKPAMSYLDIVRDVAEISDVPVAAYQISGEYSMITAAAERGWIDRDAAILESLT 302 Query: 307 SIRRAGADIVFTYWAADVACWLS 329 S RRAGA I+ TYWA +VA LS Sbjct: 303 STRRAGASIILTYWATEVALRLS 325 >tr|C2AL34|C2AL34_TSUPA Tax_Id=521096 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Tsukamurella paurometabola DSM 20162] Length = 330 Score = 432 bits (1112), Expect = e-119 Identities = 214/320 (66%), Positives = 251/320 (78%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P+ RPRRLR+TPA+RRLVA+ S+EPR LVLPMFV DGID PI+SMPGV QHT DSLR Sbjct: 3 FPQVRPRRLRTTPAVRRLVAEVSVEPRQLVLPMFVRDGIDAPVPISSMPGVQQHTLDSLR 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 L LFGVP D DKDA GSA +PDG+LN LR L +DLGDATV+MADT Sbjct: 63 AAADEAVRAGVGGLMLFGVPDDADKDAEGSASWNPDGVLNRGLRALRDDLGDATVIMADT 122 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFT HGHCGVLD +GRVDNDAT+ RY + VAQA++GA+++GPSGMMDGQIG LR Sbjct: 123 CLDEFTSHGHCGVLDAEGRVDNDATLERYALMGVAQAQAGAHMLGPSGMMDGQIGVLRSA 182 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+AG DV++ AY AK++SAFYGPFREAV SL GDRRTYQQ+ N RE+LRE+ LD+ Sbjct: 183 LDTAGQHDVSLFAYTAKYASAFYGPFREAVGSSLQGDRRTYQQDAANRRESLRELDLDVA 242 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLDV+A A SPVPVAAYQ+SGEYAMI AAA N WID +A+ ESL Sbjct: 243 EGADLVMVKPAMSYLDVLADVAAASPVPVAAYQISGEYAMITAAAQNGWIDRDSAIRESL 302 Query: 306 TSIRRAGADIVFTYWAADVA 325 SIRRAGAD+V TYWA + A Sbjct: 303 LSIRRAGADVVLTYWAVEAA 322 >tr|Q82E74|Q82E74_STRAW Tax_Id=33903 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Streptomyces avermitilis] Length = 330 Score = 422 bits (1085), Expect = e-116 Identities = 203/320 (63%), Positives = 248/320 (77%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TPA+RR+VA+T L P + +LP FV +G+ E PI +MPGVVQHTRDSL+ Sbjct: 7 FPGTRPRRLRTTPALRRMVAETRLHPADFILPAFVREGVSEPVPITAMPGVVQHTRDSLK 66 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP D KDA GSAG DPDGIL VALRD+ ++GD ++M+D Sbjct: 67 KAALEALEAGVSGIMLFGVPEDAKKDAQGSAGTDPDGILQVALRDVRAEVGDELIVMSDL 126 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLDGQGRVDNDAT+ RY E+A QA++GA+VVGPSGMMDGQIG +RD Sbjct: 127 CLDEFTDHGHCGVLDGQGRVDNDATLERYAEMAQVQADAGAHVVGPSGMMDGQIGVVRDA 186 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD G DV+ILAY AK+SSAFYGPFREAV SL GDR+TYQQ+P NARE+LRE+ LDL+ Sbjct: 187 LDQIGREDVSILAYTAKYSSAFYGPFREAVGSSLKGDRKTYQQDPANARESLRELALDLE 246 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++A A VP+AAYQ+SGEY+MI AAA WID A+LE+L Sbjct: 247 EGADMVMVKPAGPYLDILARVADAVDVPLAAYQISGEYSMIEAAAEKGWIDRDKAILETL 306 Query: 306 TSIRRAGADIVFTYWAADVA 325 T I+RAGA + TYWA +VA Sbjct: 307 TGIKRAGAQNILTYWATEVA 326 >sp|P54919|HEM2_STRCO Tax_Id=1902 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; Short=ALADH; Short=ALAD; EC=4.2.1.24; AltName: Full=Porphobilinogen synthase;[Streptomyces coelicolor] Length = 330 Score = 421 bits (1082), Expect = e-116 Identities = 204/320 (63%), Positives = 248/320 (77%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TP MRR+VA+T L P + +LP FV +G+ E PIA+MPGVVQHTRD+L+ Sbjct: 7 FPGARPRRLRTTPVMRRMVAETRLHPADFILPAFVREGVSEPVPIAAMPGVVQHTRDTLK 66 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP D KDA G+AG DPDGIL VALRD+ ++GD ++M+D Sbjct: 67 KAAAEAVEAGVSGIMLFGVPEDGKKDAAGTAGTDPDGILQVALRDVRAEVGDELLVMSDL 126 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLDGQGRVDNDAT+ RY E+A QA++GA+VVGPSGMMDGQIG +RD Sbjct: 127 CLDEFTDHGHCGVLDGQGRVDNDATLERYAEMAQVQADAGAHVVGPSGMMDGQIGVIRDA 186 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD G DVAILAY AK++SAFYGPFREAV SL GDR+TYQQ+ NARE+LRE+ LDL+ Sbjct: 187 LDQIGREDVAILAYTAKYASAFYGPFREAVGSSLKGDRKTYQQDSANARESLRELALDLE 246 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++A A S VPVAAYQ+SGEY+MI AAA WID A+LESL Sbjct: 247 EGADMVMVKPAGPYLDILAKVAEASDVPVAAYQISGEYSMIEAAAEKGWIDRDRAILESL 306 Query: 306 TSIRRAGADIVFTYWAADVA 325 T I+RAGA + TYWA +VA Sbjct: 307 TGIKRAGARNILTYWATEVA 326 >tr|B1VT97|B1VT97_STRGG Tax_Id=455632 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Streptomyces griseus subsp. griseus] Length = 335 Score = 420 bits (1080), Expect = e-115 Identities = 204/323 (63%), Positives = 249/323 (77%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TPAMRR+VA+T L+P NL+LP FV +GID IA+MPGV QHT D+LR Sbjct: 7 FPGSRPRRLRTTPAMRRMVAETRLDPANLILPAFVREGIDAPVAIAAMPGVYQHTLDTLR 66 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + +FGVP D+ KDA G+AG DPDGIL VALR + E++GD V+M+D Sbjct: 67 KAAVEAVSAGVSGIMVFGVPEDEKKDARGTAGTDPDGILQVALRAVREEVGDDLVIMSDL 126 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDE+TDHGHCGVL GRVDNDAT+ RY E+A QA++GA+VVGPSGMMDGQ+G +RD Sbjct: 127 CLDEYTDHGHCGVLTADGRVDNDATLERYAEMAQVQADAGAHVVGPSGMMDGQVGVVRDA 186 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD G+ DV+ILAYA K+SSAFYGPFREAV SL+GDR+TYQQ+P NARE+LRE+ LDL Sbjct: 187 LDQTGHEDVSILAYAVKYSSAFYGPFREAVGSSLTGDRKTYQQDPANARESLRELALDLA 246 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++A A VPVAAYQ+SGEYAMI AAA WID A+LESL Sbjct: 247 EGADMVMVKPAGPYLDILAKVAESVDVPVAAYQISGEYAMIEAAAERGWIDRDKAILESL 306 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 T IRRAGA ++ TYWA + A WL Sbjct: 307 TGIRRAGARMILTYWATEAAQWL 329 >tr|B4V345|B4V345_9ACTO Tax_Id=465541 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Streptomyces sp. Mg1] Length = 333 Score = 419 bits (1076), Expect = e-115 Identities = 199/323 (61%), Positives = 250/323 (77%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TPAMRR+VA+T L P +L+LP FV +GI E I++MPGVVQHTRD+LR Sbjct: 7 FPGSRPRRLRTTPAMRRMVAETRLHPSDLILPAFVREGISEPAAISAMPGVVQHTRDTLR 66 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP D++KDA G+AG +PDGIL +A+RD+ ++GD V+M+D Sbjct: 67 KAAVEAVEAGVSGIMLFGVPADENKDALGTAGTEPDGILQLAIRDVRAEVGDDLVIMSDL 126 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDE+TDHGHCGVLD GRVDNDAT+ RY E+A QA++G +VVGPSGMMDGQ+G +RD Sbjct: 127 CLDEYTDHGHCGVLDENGRVDNDATLERYAEMAQVQADAGVHVVGPSGMMDGQVGVIRDA 186 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD G+ DV+ILAY AK+SSAFYGPFREAV SL GDR+TYQQ+P NARE+LRE+ LDLD Sbjct: 187 LDETGHEDVSILAYTAKYSSAFYGPFREAVGSSLQGDRKTYQQDPANARESLRELALDLD 246 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++ A VPV+AYQ+SGE+AMI AAA WI+ A+LESL Sbjct: 247 EGADMVMVKPAGPYLDILHRVAQAVDVPVSAYQISGEFAMIEAAAERGWIERDRAILESL 306 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 I+RAGAD + TYWA +VA WL Sbjct: 307 LGIKRAGADTILTYWATEVAGWL 329 >tr|B5GNL9|B5GNL9_STRCL Tax_Id=443255 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Streptomyces clavuligerus ATCC 27064] Length = 329 Score = 417 bits (1073), Expect = e-115 Identities = 198/320 (61%), Positives = 249/320 (77%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TPA+RR+VA+T L P +L+LP FV +G+ E PI++MPGVVQHTRD+LR Sbjct: 7 FPGARPRRLRTTPAVRRMVAETRLHPADLILPAFVREGVSEPVPISAMPGVVQHTRDTLR 66 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP D KDA G+AG DPDGIL VA+RD+ ++GD V+M+D Sbjct: 67 KAAVEARAAGVAGIMLFGVPEDSKKDALGTAGTDPDGILQVAIRDVRSEVGDDLVIMSDL 126 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDE+TDHGHCGVLD GRVDNDAT+ RY E+A QA++G ++VGPSGMMDGQ+G +RD Sbjct: 127 CLDEYTDHGHCGVLDADGRVDNDATLERYAEMAQVQADAGVHMVGPSGMMDGQVGVIRDA 186 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+ G DV+ILAY AK+SSAFYGPFREAV SL+GDR+TYQQ+ N RE+LRE+ LDLD Sbjct: 187 LDTIGKEDVSILAYTAKYSSAFYGPFREAVGSSLTGDRKTYQQDSANVRESLRELALDLD 246 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGADI+M+KPA YLDV+A A VPVAAYQ+SGEY+M+ AAA W+D A+LE+L Sbjct: 247 EGADIVMVKPAGPYLDVLAKIAESVSVPVAAYQISGEYSMVEAAAEKGWVDREKAILETL 306 Query: 306 TSIRRAGADIVFTYWAADVA 325 T I+RAGAD++ TYWA +VA Sbjct: 307 TGIKRAGADMILTYWATEVA 326 >tr|C6WNG0|C6WNG0_ACTMD Tax_Id=446462 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Actinosynnema mirum] Length = 324 Score = 416 bits (1068), Expect = e-114 Identities = 207/323 (64%), Positives = 242/323 (74%), Gaps = 2/323 (0%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P HRPRRLR+TPAMRRLVA+T + P LVLP FV +G E IASMPGV QH+RDSLR Sbjct: 2 FPSHRPRRLRTTPAMRRLVAETEVRPSQLVLPAFVKEGAREPVEIASMPGVFQHSRDSLR 61 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP + +DA GS DPDGILN AL DL +LGD TVLM+D Sbjct: 62 KAAVEAVEAGVGGIMLFGVPAE--RDAVGSGATDPDGILNAALADLRSELGDTTVLMSDC 119 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVL G VDNDAT+ Y E+AVAQA +GA++VGPSGMMDGQ+G +R+ Sbjct: 120 CLDEFTDHGHCGVLAADGTVDNDATLEVYGEMAVAQARAGAHLVGPSGMMDGQVGFIRNA 179 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD AG+ D ILAY AK+SSA YGPFR+AV L GDR+TYQQ+P N RE+LRE+ LDL Sbjct: 180 LDEAGFTDTGILAYTAKYSSALYGPFRDAVESQLKGDRKTYQQDPANVRESLRELALDLA 239 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLDV+ A S VPVAAYQ+SGEYAM+ AAAAN WI+ VLE L Sbjct: 240 EGADVVMVKPALPYLDVLRQVADASDVPVAAYQISGEYAMVEAAAANGWIERERTVLELL 299 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 TSIRRAGADIV TYWAA+ A WL Sbjct: 300 TSIRRAGADIVLTYWAAEAATWL 322 >tr|C9N6G4|C9N6G4_9ACTO Tax_Id=591167 SubName: Full=Porphobilinogen synthase; EC=4.2.1.24;[Streptomyces flavogriseus ATCC 33331] Length = 331 Score = 413 bits (1062), Expect = e-113 Identities = 200/320 (62%), Positives = 246/320 (76%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TP MRR+VA+T L+P NL+LP FV +GID I++MPGV QHT D+LR Sbjct: 7 FPGSRPRRLRTTPVMRRMVAETRLDPANLILPAFVREGIDAPVAISAMPGVQQHTLDTLR 66 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP D+ KDA G+AG DP+GIL V LR + E++GD V+M+D Sbjct: 67 KAAVDAVAAGVSGIMLFGVPLDEKKDARGTAGTDPEGILQVGLRAVREEVGDDLVIMSDL 126 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDE+TDHGHCGVL GRVDNDAT+ RY E+A QA++GA+VVGPSGMMDGQ+G +RD Sbjct: 127 CLDEYTDHGHCGVLTEDGRVDNDATLERYAEMAQVQADAGAHVVGPSGMMDGQVGVIRDA 186 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD G+ DV+ILAY AK+SSAFYGPFREAV SL GDR+TYQQ+P N RE+LRE+ LDL+ Sbjct: 187 LDQTGHEDVSILAYTAKYSSAFYGPFREAVGSSLQGDRKTYQQDPANIRESLRELALDLE 246 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++A A VPVAAYQ+SGEYAMI AAA WID AA+LESL Sbjct: 247 EGADMVMVKPAGPYLDILAKVADAVDVPVAAYQISGEYAMIEAAAEKGWIDRDAAILESL 306 Query: 306 TSIRRAGADIVFTYWAADVA 325 T IRRAGA ++ TYWA +VA Sbjct: 307 TGIRRAGARMILTYWATEVA 326 >tr|B8HBR4|B8HBR4_ARTCA Tax_Id=452863 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Arthrobacter chlorophenolicus] Length = 327 Score = 412 bits (1059), Expect = e-113 Identities = 200/323 (61%), Positives = 247/323 (76%), Gaps = 2/323 (0%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TPAMRRL A+T L L+LP F+ +GI E PI SMPGVVQHT DSL+ Sbjct: 3 FPSQRPRRLRTTPAMRRLTAETRLASAELILPAFIREGITEPNPITSMPGVVQHTSDSLK 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 R + LFG+P + +DA G+A +DP G+LN A+RD+ ++GD V+M+D Sbjct: 63 RAAAEAVELGLGGIMLFGIP--ETRDAEGTASLDPQGVLNKAIRDVRAEVGDDLVIMSDV 120 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLD G VDND TV Y +AVAQAE+GA+++GPSGMMDGQI A+R Sbjct: 121 CLDEFTDHGHCGVLDADGYVDNDRTVEIYARMAVAQAEAGAHMLGPSGMMDGQIAAIRAA 180 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD AG+A+ +++AY+AK++SAFYGPFREAV L GDRRTYQ + GN EALRE++LDL Sbjct: 181 LDDAGHANTSVIAYSAKYASAFYGPFREAVDSQLKGDRRTYQMDAGNRTEALREVELDLA 240 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGADI+M+KPA YLD+VA A +SPVPVAAYQ+SGEYAMI AAAAN WID RAA+ ES+ Sbjct: 241 EGADIVMVKPAMSYLDIVADVAAMSPVPVAAYQISGEYAMIEAAAANGWIDRRAAIAESV 300 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 IRRAGA +V TYWAA++A WL Sbjct: 301 LGIRRAGAHMVLTYWAAELAGWL 323 >tr|B5HKN3|B5HKN3_STRPR Tax_Id=457429 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Streptomyces pristinaespiralis ATCC 25486] Length = 333 Score = 412 bits (1059), Expect = e-113 Identities = 198/324 (61%), Positives = 248/324 (76%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+TPA+RR+VA+T L P +L+LP FV +GI E PI++MPGVVQHTRD+LR Sbjct: 7 FPGARPRRLRTTPAVRRMVAETRLHPADLILPAFVREGISEPVPISAMPGVVQHTRDTLR 66 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP D+ KDA G+AG DPDGIL VA+RD+ ++GD V+M+D Sbjct: 67 KAAVEAREAGVAGIMLFGVPEDEKKDALGTAGTDPDGILQVAIRDVKAEVGDELVIMSDL 126 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDE+TDHGHCGVL GRVDNDAT+ RY E+A QA++G +VVGPSGMMDGQIG +RD Sbjct: 127 CLDEYTDHGHCGVLAADGRVDNDATLERYAEMAQVQADAGVHVVGPSGMMDGQIGVVRDA 186 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+ G DV+ILAY AK+SSAFYGPFREAV SL GDR+TYQQ+P N RE++RE+ LDL+ Sbjct: 187 LDTIGKEDVSILAYTAKYSSAFYGPFREAVGSSLKGDRKTYQQDPANVRESMRELALDLE 246 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLDV+A A VPVAAYQ+SGEYAM+ AAA WID A+ E+L Sbjct: 247 EGADMVMVKPAGPYLDVLAKVADAVDVPVAAYQISGEYAMVEAAAEKGWIDRDKAIAETL 306 Query: 306 TSIRRAGADIVFTYWAADVACWLS 329 I+RAGA ++ TYWA +VA +S Sbjct: 307 LGIKRAGASMILTYWATEVAQGIS 330 >tr|B5GKE2|B5GKE2_9ACTO Tax_Id=465543 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Streptomyces sp. SPB74] Length = 331 Score = 407 bits (1047), Expect = e-112 Identities = 200/321 (62%), Positives = 240/321 (74%) Query: 5 GYPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSL 64 G+P RPRRLR+ MRR+VA+T L+P + +LP FV +GI E I +MPGVVQHTRD+L Sbjct: 7 GFPGVRPRRLRTNATMRRMVAETRLDPADFILPAFVREGIAEPVAIGTMPGVVQHTRDTL 66 Query: 65 RRXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMAD 124 R+ + LFGVP D KD GSAG DPDGIL ALRD+ ++GD ++M+D Sbjct: 67 RKAAVEAAEAGVSGIMLFGVPEDAKKDGVGSAGTDPDGILQQALRDVRAEVGDVLLVMSD 126 Query: 125 TCLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRD 184 CLDEFTDHGHCGVLD GRVDNDAT+ RY E+A QA++GA+VVGPSGMMDGQ+G +RD Sbjct: 127 LCLDEFTDHGHCGVLDAHGRVDNDATLERYAEMAQVQADAGAHVVGPSGMMDGQVGVIRD 186 Query: 185 GLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDL 244 LD G+ DVAILAY AK++SAFYGPFREAV SL+GDR+TYQQ+P N RE+LRE+ LDL Sbjct: 187 ALDQTGHEDVAILAYTAKYASAFYGPFREAVGSSLTGDRKTYQQDPANLRESLRELALDL 246 Query: 245 DEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLES 304 EGAD++M+KPA YLDV+A A VPV AYQ+SGEYAMI AAA WID AA+ ES Sbjct: 247 QEGADMVMVKPAGPYLDVLAKVAESVDVPVVAYQISGEYAMIEAAAERGWIDREAAIRES 306 Query: 305 LTSIRRAGADIVFTYWAADVA 325 L IRRAGA V TYWA +VA Sbjct: 307 LLGIRRAGARNVLTYWAVEVA 327 >tr|C7MH06|C7MH06_BRAFD Tax_Id=446465 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Brachybacterium faecium] Length = 340 Score = 406 bits (1044), Expect = e-111 Identities = 205/321 (63%), Positives = 244/321 (76%), Gaps = 2/321 (0%) Query: 7 PRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRR 66 P RPRRLR++ AMR LV + +L P +LVLPMFV +G E RP++SMPGV QHT DSL R Sbjct: 9 PIDRPRRLRTSTAMRSLVREHTLRPADLVLPMFVREGATENRPVSSMPGVEQHTLDSLAR 68 Query: 67 XXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTC 126 + LFGVP + KDA GS DP+GILN AL L +LGD+TV+MAD C Sbjct: 69 AATEAVERGVGGVMLFGVP--EHKDAVGSGATDPEGILNRALARLRSELGDSTVIMADLC 126 Query: 127 LDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGL 186 LDEFTDHGHCGVLD GRVDNDAT+ RY E+A+AQAE+GA+++GPSGMMDGQI A+RD L Sbjct: 127 LDEFTDHGHCGVLDDAGRVDNDATLGRYREMALAQAEAGAHLLGPSGMMDGQIAAVRDAL 186 Query: 187 DSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDE 246 DSAG+ D A+ AY AK++SAFYGPFREAV SL GDRRTYQQ+P N REALRE++LD+ E Sbjct: 187 DSAGHQDTAVYAYTAKYASAFYGPFREAVDSSLQGDRRTYQQDPANGREALRELELDVAE 246 Query: 247 GADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLT 306 GAD++M+KP YLDV+ +G SPVPV AYQVSGEYAMI AAAAN WID VLESL Sbjct: 247 GADLVMVKPGLPYLDVLREISGASPVPVGAYQVSGEYAMIEAAAANGWIDRDRTVLESLL 306 Query: 307 SIRRAGADIVFTYWAADVACW 327 + RRAGA V TY+A++VA W Sbjct: 307 AFRRAGASTVLTYYASEVAGW 327 >tr|A1R8A0|A1R8A0_ARTAT Tax_Id=290340 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Arthrobacter aurescens] Length = 326 Score = 406 bits (1043), Expect = e-111 Identities = 193/323 (59%), Positives = 248/323 (76%), Gaps = 2/323 (0%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P HRPRRLR+TPAMRRL A+ L P +L+LP F+ +G+ E PI+SMPGVVQHT +SL+ Sbjct: 3 FPNHRPRRLRTTPAMRRLTAENRLAPADLILPAFIREGLTEPSPISSMPGVVQHTTESLK 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 R + LFGVP +DA G+A +DPDG+LN A+RD+ ++GD V+M D Sbjct: 63 RAAAEAVELGVGGIMLFGVPAV--RDAQGTASLDPDGVLNKAIRDVKAEVGDDLVIMGDV 120 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLD +G VDNDAT+ Y +AVAQA++GA+V+GPSGMMDGQI +R Sbjct: 121 CLDEFTDHGHCGVLDSEGYVDNDATLEIYGRMAVAQADAGAHVLGPSGMMDGQIAVIRQA 180 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 L+ +G+ + A+LAYAAK++SAFYGPFREAV L GDRRTYQ + N REA+ E++LDL+ Sbjct: 181 LEESGHKNTAVLAYAAKYASAFYGPFREAVDSQLKGDRRTYQMDAANRREAILEVELDLE 240 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++A A +SPVPV+AYQ+SGEYAMI AAAAN WID R A+ ES+ Sbjct: 241 EGADMVMVKPAMSYLDILADVAAMSPVPVSAYQISGEYAMIEAAAANGWIDRRGAITESV 300 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 I+RAGAD V TYWA+++A WL Sbjct: 301 LGIKRAGADTVLTYWASELAGWL 323 >tr|B5I6Y3|B5I6Y3_9ACTO Tax_Id=463191 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Streptomyces sviceus ATCC 29083] Length = 330 Score = 405 bits (1042), Expect = e-111 Identities = 195/320 (60%), Positives = 242/320 (75%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P RPRRLR+ P MRR+VA+T L P + +LP FV +G E PI++MPGVVQHTRDSL+ Sbjct: 7 FPGTRPRRLRTNPVMRRMVAETRLHPADFILPAFVLEGASEPVPISAMPGVVQHTRDSLK 66 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP + KDA G+ G DPDGIL VA+RD+ ++GD ++M+D Sbjct: 67 KAAAEAVAAGVSGIMLFGVPEESKKDAVGTPGTDPDGILQVAIRDVRAEVGDDLLVMSDL 126 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDE DHGHCGVLD QGRVDNDAT+ RY E+A QA++GA+VVGPSGMMDGQ+G +RD Sbjct: 127 CLDETVDHGHCGVLDDQGRVDNDATLERYAEMAQVQADAGAHVVGPSGMMDGQVGVIRDA 186 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD G DVAILAY AK++SAFYGPFREAV+ SL GDR+TYQQ+P N RE+LRE+ LDL+ Sbjct: 187 LDQIGREDVAILAYTAKYASAFYGPFREAVASSLQGDRKTYQQDPANVRESLRELALDLE 246 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLDV+A A VPVAAYQ+SGEY+MI AAA WID A+LE+L Sbjct: 247 EGADMVMVKPAGPYLDVLARVADAVDVPVAAYQISGEYSMIEAAAEKGWIDRDRAILETL 306 Query: 306 TSIRRAGADIVFTYWAADVA 325 T I+RAGA + TYWA +VA Sbjct: 307 TGIKRAGAQNILTYWATEVA 326 >tr|Q4JSX7|Q4JSX7_CORJK Tax_Id=306537 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Corynebacterium jeikeium] Length = 334 Score = 405 bits (1041), Expect = e-111 Identities = 202/323 (62%), Positives = 244/323 (75%), Gaps = 4/323 (1%) Query: 7 PRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRR 66 P RPRRLR+TP MR A+T L P LVLPMF+ADG+D R I S+PGV QHT DSL R Sbjct: 7 PFRRPRRLRTTPQMRNFTAETDLNPNRLVLPMFIADGLDAPRDITSLPGVQQHTEDSLLR 66 Query: 67 XXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTC 126 ++LFGVP D+DKDATGS V DGILN LR + E GD ++MADTC Sbjct: 67 AVEEAANAGVGSIDLFGVPLDEDKDATGSQAVAEDGILNRGLRAVRERFGDDILVMADTC 126 Query: 127 LDEFTDHGHCGVLD----GQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGAL 182 LDEFTDHGHCGVL G VDNDAT+ +Y ++AVAQAE+GA++V PSGMMDGQI + Sbjct: 127 LDEFTDHGHCGVLSTDRYGHKIVDNDATLPQYAKMAVAQAEAGAHIVSPSGMMDGQIRHI 186 Query: 183 RDGLDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKL 242 R+ LD AG+ DV+I+AY+AK++SAF+GPFREAV SL GDRRTYQQ+P N RE++ E +L Sbjct: 187 REALDEAGHQDVSIMAYSAKYASAFFGPFREAVGSSLQGDRRTYQQDPRNLRESILETQL 246 Query: 243 DLDEGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVL 302 D+DEGAD++M+KPA YLDV++ A +SPVPVAAYQVSGEYAMI AAA N WIDE AA++ Sbjct: 247 DIDEGADMVMVKPAMPYLDVLSEVADMSPVPVAAYQVSGEYAMISAAAQNGWIDEEAAIM 306 Query: 303 ESLTSIRRAGADIVFTYWAADVA 325 ES+ IRRAGADI+ TYWA VA Sbjct: 307 ESIYGIRRAGADIILTYWATRVA 329 >tr|B2GL26|B2GL26_KOCRD Tax_Id=378753 (hemB)RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Kocuria rhizophila] Length = 334 Score = 404 bits (1039), Expect = e-111 Identities = 195/319 (61%), Positives = 250/319 (78%), Gaps = 2/319 (0%) Query: 10 RPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRRXXX 69 RPRRLRSTPAMRR VA+T ++P +L+LP+FV +G+ E +P++SMPGVVQH+ DSLRR Sbjct: 12 RPRRLRSTPAMRRFVAETRVDPSDLILPVFVREGLSEPQPLSSMPGVVQHSMDSLRRAAA 71 Query: 70 XXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTCLDE 129 +FGVP + +DA GSA +DPDGILN +R + E++GD V+MAD CLDE Sbjct: 72 EAVELGLGGFMIFGVP--ETRDAEGSAALDPDGILNRGIRAVREEVGDGVVVMADLCLDE 129 Query: 130 FTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGLDSA 189 FTDHGHCGVLD +GRVDND T+ Y +AVAQAE+GA+++GPSGMMDGQ+G +R LD+A Sbjct: 130 FTDHGHCGVLDARGRVDNDRTLEIYGRMAVAQAEAGAHMLGPSGMMDGQVGVIRAALDAA 189 Query: 190 GYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDEGAD 249 G+ DV+ILAY AK+SSAFYGPFREAV +L+GDR+TYQ +P N REAL E++ DL EGAD Sbjct: 190 GHEDVSILAYTAKYSSAFYGPFREAVDSTLTGDRKTYQMDPANRREALLELQTDLAEGAD 249 Query: 250 IIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLTSIR 309 ++M+KPA YLD++ A SPVPV+AYQ+SGEYAMI AA+AN WID AA+ ES+ SI+ Sbjct: 250 MVMVKPAMSYLDILREIADASPVPVSAYQISGEYAMIEAASANGWIDREAAIRESVLSIK 309 Query: 310 RAGADIVFTYWAADVACWL 328 RAGAD + TY+A ++A WL Sbjct: 310 RAGADSILTYYATELAGWL 328 >tr|A0JYM4|A0JYM4_ARTS2 Tax_Id=290399 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Arthrobacter sp.] Length = 327 Score = 404 bits (1038), Expect = e-111 Identities = 191/323 (59%), Positives = 249/323 (77%), Gaps = 2/323 (0%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 +P HRPRRLR+TPAMRR+ A+ L L+LP F+ +G+ E PIASMPGVVQHT DSL+ Sbjct: 3 FPTHRPRRLRTTPAMRRMTAENRLAAPELILPAFIREGLTEPNPIASMPGVVQHTTDSLK 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFG+P + +DA G+A +DPDG+LN A+RD+ ++GD V+M+D Sbjct: 63 KAAAEAVELGVGGIMLFGIPAE--RDARGTASLDPDGVLNKAIRDVRAEVGDDLVVMSDV 120 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFTDHGHCGVLD +G VDNDAT+ Y +AVAQA++GA+++GPSGMMDGQIG +R Sbjct: 121 CLDEFTDHGHCGVLDDEGYVDNDATLEIYAAMAVAQADAGAHMLGPSGMMDGQIGVIRQA 180 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 L+ AG+ + A++AYAAK++SAFYGPFREAV L GDRRTYQ + N REAL E++LDL Sbjct: 181 LEDAGHTNTAVVAYAAKYASAFYGPFREAVDSQLKGDRRTYQMDSANRREALLEVELDLA 240 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLD++A A +S VPVAAYQ+SGEY+MI AAAAN WID RAA+ ES+ Sbjct: 241 EGADLVMVKPAMSYLDILADVAAISTVPVAAYQISGEYSMIEAAAANGWIDRRAAITESV 300 Query: 306 TSIRRAGADIVFTYWAADVACWL 328 I+RAGA++V TYWA+++A WL Sbjct: 301 LGIKRAGANMVLTYWASELAGWL 323 >tr|B1VEK0|B1VEK0_CORU7 Tax_Id=504474 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Corynebacterium urealyticum] Length = 352 Score = 403 bits (1036), Expect = e-110 Identities = 198/320 (61%), Positives = 245/320 (76%), Gaps = 4/320 (1%) Query: 10 RPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRRXXX 69 RPRRLR+ P MR A+TSL P LVLPMFVADG+ + +PI+S+PGV QHT DSL R Sbjct: 28 RPRRLRTNPVMRDFTAETSLNPSQLVLPMFVADGLTDAKPISSLPGVYQHTTDSLLRAVE 87 Query: 70 XXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTCLDE 129 ++LFGVP D+DKDATGS GVDP+GILN LR + ++ G+ ++MADTCLDE Sbjct: 88 EAAEAGVGSIDLFGVPLDEDKDATGSVGVDPEGILNKNLRAIRKEFGNDILVMADTCLDE 147 Query: 130 FTDHGHCGVLD----GQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 FTDHGHCGV G VDNDAT+ +Y LAVAQA++GA++V PSGMMDGQ+ +R Sbjct: 148 FTDHGHCGVQGEDAFGHQIVDNDATLEQYAALAVAQADAGAHIVSPSGMMDGQVAVIRAA 207 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD++G+ DV+I+AY+AK++SAFYGPFREAV SL+GDRRTYQQ+P N RE+L E ++D+D Sbjct: 208 LDASGHEDVSIMAYSAKYASAFYGPFREAVGSSLTGDRRTYQQDPRNRRESLLETQMDID 267 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGAD++M+KPA YLDV+ A +SPVPVAAYQVSGEYAMI AAA N WID A++ESL Sbjct: 268 EGADMVMVKPAMPYLDVLREVADMSPVPVAAYQVSGEYAMISAAAQNGWIDLEPAIMESL 327 Query: 306 TSIRRAGADIVFTYWAADVA 325 T IRRAGADI+ TYWA A Sbjct: 328 TGIRRAGADIILTYWATTAA 347 >tr|A8LZJ2|A8LZJ2_SALAI Tax_Id=391037 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Salinispora arenicola] Length = 327 Score = 402 bits (1033), Expect = e-110 Identities = 196/320 (61%), Positives = 245/320 (76%), Gaps = 2/320 (0%) Query: 6 YPRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLR 65 YP RPRRLR + A+RRLVA+T ++P LV+P+FV +G+ E R +AS+PGV+QHTR+SLR Sbjct: 3 YPEIRPRRLRRSTALRRLVAETRVDPAELVVPLFVKEGLTEPRAVASLPGVLQHTRESLR 62 Query: 66 RXXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADT 125 + + LFGVP +D+ GS G DP+GILN A+RD+ ++GDATV+M+D Sbjct: 63 KAAVAAVQAGVGGIMLFGVPATRDE--RGSGGADPNGILNAAIRDVVSEVGDATVVMSDL 120 Query: 126 CLDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDG 185 CLDEFT HGHCG+L G V NDAT+A Y E+AVAQAE+G +VVGPSGMMDGQ+GA+R Sbjct: 121 CLDEFTSHGHCGLLTPDGSVANDATLAAYAEMAVAQAEAGVHVVGPSGMMDGQVGAVRQA 180 Query: 186 LDSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLD 245 LD+AG+ DV ILAY AK++SAFYGPFR+AV +L GDRRTYQQ+P N RE+LRE+ LD+ Sbjct: 181 LDAAGHRDVTILAYTAKYASAFYGPFRDAVESTLDGDRRTYQQDPANLRESLREVALDVA 240 Query: 246 EGADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESL 305 EGADI+M+KPA YLDVVA VPVAAYQVSGEYAM+ AAAAN WID ++E+L Sbjct: 241 EGADIVMVKPALPYLDVVAAVRAAVDVPVAAYQVSGEYAMVEAAAANGWIDRERVMVETL 300 Query: 306 TSIRRAGADIVFTYWAADVA 325 TSIRRAGA I+ TYWA + A Sbjct: 301 TSIRRAGAQIILTYWAVEAA 320 >tr|A1SE04|A1SE04_NOCSJ Tax_Id=196162 RecName: Full=Delta-aminolevulinic acid dehydratase; EC=4.2.1.24;[Nocardioides sp.] Length = 333 Score = 402 bits (1032), Expect = e-110 Identities = 197/319 (61%), Positives = 246/319 (77%), Gaps = 2/319 (0%) Query: 7 PRHRPRRLRSTPAMRRLVAQTSLEPRNLVLPMFVADGIDELRPIASMPGVVQHTRDSLRR 66 P RPRRLR+T A+RR+V++TSLE R LVLP+FV +G+DE RPI+SMPGVVQHTR SL Sbjct: 12 PTVRPRRLRTTAALRRMVSETSLEARQLVLPVFVCEGLDEPRPISSMPGVVQHTRSSLLA 71 Query: 67 XXXXXXXXXXXXLNLFGVPRDQDKDATGSAGVDPDGILNVALRDLAEDLGDATVLMADTC 126 + LFG+P + KDA GS VDP GILN+A+ D+ ++GDA +M+D C Sbjct: 72 AVTEAAELGLGGVMLFGIP--ERKDAVGSGAVDPAGILNLAITDVVGEVGDALTVMSDLC 129 Query: 127 LDEFTDHGHCGVLDGQGRVDNDATVARYVELAVAQAESGANVVGPSGMMDGQIGALRDGL 186 LDEFTDHGHCGVL G+VDND T++RY E+A+AQA +G ++VGPSGMMDGQ+ +R L Sbjct: 130 LDEFTDHGHCGVLTPDGKVDNDRTLSRYAEMALAQAHAGVDMVGPSGMMDGQVAVVRRAL 189 Query: 187 DSAGYADVAILAYAAKFSSAFYGPFREAVSCSLSGDRRTYQQEPGNAREALREIKLDLDE 246 D+AG+ DV+ILAY+AK++SAF+GPFREAV SL GDRRTYQQ+P NARE +RE LD++E Sbjct: 190 DAAGHTDVSILAYSAKYASAFFGPFREAVDSSLEGDRRTYQQDPANAREGVREAMLDVEE 249 Query: 247 GADIIMIKPASGYLDVVATAAGVSPVPVAAYQVSGEYAMICAAAANNWIDERAAVLESLT 306 GAD++M+KPA YLDV+ VPVAAY VSGEYAM+ AAAA WID A+LE+LT Sbjct: 250 GADLVMVKPALAYLDVLHRVRDAVDVPVAAYNVSGEYAMLEAAAAKGWIDREPAILEALT 309 Query: 307 SIRRAGADIVFTYWAADVA 325 SIRRAGAD+V TYWAA+VA Sbjct: 310 SIRRAGADVVLTYWAAEVA 328 Database: Amellifera_nr Posted date: Jan 15, 2010 5:10 AM Number of letters in database: 3,808,957,724 Number of sequences in database: 11,153,314 Lambda K H 0.319 0.135 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11153314 Number of Hits to DB: 2,355,217,949 Number of extensions: 95178733 Number of successful extensions: 243542 Number of sequences better than 10.0: 1768 Number of HSP's gapped: 240359 Number of HSP's successfully gapped: 1772 Length of query: 329 Length of database: 3,808,957,724 Length adjustment: 137 Effective length of query: 192 Effective length of database: 2,280,953,706 Effective search space: 437943111552 Effective search space used: 437943111552 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 80 (35.4 bits)