BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_0402 (2559 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|Q3L891|Q3L891_MYCS2 Tax_Id=246196 (mps2)SubName: Full=Linear ... 4856 0.0 tr|Q9RLP6|Q9RLP6_MYCSM Tax_Id=1772 (mps)SubName: Full=Peptide sy... 4856 0.0 tr|A5A9R5|A5A9R5_MYCCH Tax_Id=1774 (mps2)SubName: Full=MPS2 prot... 3573 0.0 tr|B1MIF0|B1MIF0_MYCA9 Tax_Id=561007 SubName: Full=Probable pept... 3549 0.0 tr|A5A9U3|A5A9U3_MYCAB Tax_Id=36809 (mps2)SubName: Full=Mps2 pro... 3549 0.0 tr|Q9XCF2|Q9XCF2_MYCAV Tax_Id=1764 (pstB)SubName: Full=PstB;[Myc... 3501 0.0 tr|A0QHN7|A0QHN7_MYCA1 Tax_Id=243243 SubName: Full=Linear gramic... 3497 0.0 tr|D5P2M5|D5P2M5_9MYCO Tax_Id=525368 SubName: Full=Linear gramic... 3496 0.0 tr|B1MDS4|B1MDS4_MYCA9 Tax_Id=561007 SubName: Full=Probable pept... 3220 0.0 tr|A0QYM8|A0QYM8_MYCS2 Tax_Id=246196 SubName: Full=Linear gramic... 3105 0.0 tr|D5P396|D5P396_9MYCO Tax_Id=525368 SubName: Full=Linear gramic... 2657 0.0 tr|A0QH53|A0QH53_MYCA1 Tax_Id=243243 SubName: Full=Linear gramic... 2647 0.0 tr|Q3L892|Q3L892_MYCS2 Tax_Id=246196 (mps1)SubName: Full=Non-rib... 2646 0.0 tr|D5P2M4|D5P2M4_9MYCO Tax_Id=525368 SubName: Full=Linear gramic... 2597 0.0 tr|Q740V0|Q740V0_MYCPA Tax_Id=1770 (pstA)SubName: Full=PstA;[Myc... 2580 0.0 tr|A0QHN8|A0QHN8_MYCA1 Tax_Id=243243 SubName: Full=Linear gramic... 2572 0.0 tr|Q9XCF3|Q9XCF3_MYCAV Tax_Id=1764 (pstA)SubName: Full=PstA;[Myc... 2555 0.0 tr|B1MIF1|B1MIF1_MYCA9 Tax_Id=561007 SubName: Full=Probable non-... 2548 0.0 tr|A5A9U2|A5A9U2_MYCAB Tax_Id=36809 (mps1)SubName: Full=Mps1 pro... 2548 0.0 tr|D5P2M6|D5P2M6_9MYCO Tax_Id=525368 SubName: Full=Syringomycin ... 2542 0.0 tr|A5A9R4|A5A9R4_MYCCH Tax_Id=1774 (mps1)SubName: Full=MPS1 prot... 2542 0.0 tr|A0QHN3|A0QHN3_MYCA1 Tax_Id=243243 SubName: Full=Syringomycin ... 2541 0.0 tr|A0QPH5|A0QPH5_MYCS2 Tax_Id=246196 SubName: Full=Peptide synth... 2520 0.0 tr|B1MLB4|B1MLB4_MYCA9 Tax_Id=561007 SubName: Full=Probable non-... 2484 0.0 tr|B2HJA1|B2HJA1_MYCMM Tax_Id=216594 SubName: Full=Non-ribosomal... 2333 0.0 tr|B2HRT9|B2HRT9_MYCMM Tax_Id=216594 SubName: Full=Non-ribosomal... 2169 0.0 tr|Q740D1|Q740D1_MYCPA Tax_Id=1770 SubName: Full=Putative unchar... 2153 0.0 tr|B1MLB3|B1MLB3_MYCA9 Tax_Id=561007 SubName: Full=Probable non-... 1709 0.0 tr|D6A934|D6A934_9ACTO Tax_Id=566461 SubName: Full=Amino acid ad... 1363 0.0 tr|C1AUS1|C1AUS1_RHOOB Tax_Id=632772 SubName: Full=Putative non-... 1360 0.0 tr|Q9ZET7|Q9ZET7_MYCSM Tax_Id=1772 (peptide synthetase)SubName: ... 1358 0.0 tr|D2B247|D2B247_STRRD Tax_Id=479432 SubName: Full=Non-ribosomal... 1357 0.0 tr|B1VL65|B1VL65_STRGG Tax_Id=455632 SubName: Full=Putative NRPS... 1347 0.0 tr|D1WS61|D1WS61_9ACTO Tax_Id=649189 SubName: Full=Amino acid ad... 1346 0.0 tr|Q0S6F3|Q0S6F3_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal... 1345 0.0 tr|Q9Z4X6|Q9Z4X6_STRCO Tax_Id=1902 (cdaPSI)SubName: Full=CDA pep... 1342 0.0 tr|D6ES40|D6ES40_STRLI Tax_Id=457428 SubName: Full=CDA peptide s... 1339 0.0 tr|Q0S6F2|Q0S6F2_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal... 1338 0.0 tr|D5PLG3|D5PLG3_COREQ Tax_Id=525370 (ppx8)SubName: Full=Exopoly... 1338 0.0 tr|Q50E74|Q50E74_STRFL Tax_Id=67294 (dptA)SubName: Full=Peptide ... 1330 0.0 tr|D6AH54|D6AH54_STRFL Tax_Id=457431 SubName: Full=Peptide synth... 1330 0.0 tr|C1AUS0|C1AUS0_RHOOB Tax_Id=632772 SubName: Full=Putative non-... 1329 0.0 tr|Q0SKF9|Q0SKF9_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal... 1329 0.0 tr|D5PTH5|D5PTH5_COREQ Tax_Id=525370 SubName: Full=Non-ribosomal... 1328 0.0 tr|A5WIF6|A5WIF6_MYCTF Tax_Id=336982 SubName: Full=Peptide synth... 1326 0.0 >tr|Q3L891|Q3L891_MYCS2 Tax_Id=246196 (mps2)SubName: Full=Linear gramicidin synthetase subunit D; EC=1.-.-.-; EC=5.1.1.-; SubName: Full=Non-ribosomal peptide synthetase;[Mycobacterium smegmatis] Length = 2559 Score = 4856 bits (12595), Expect = 0.0 Identities = 2464/2559 (96%), Positives = 2464/2559 (96%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL Sbjct: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP Sbjct: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP Sbjct: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI Sbjct: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG Sbjct: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPL LFVLDKW Sbjct: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLTAGTGVAPIGAPVPGAALFVLDKW 360 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ Sbjct: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP Sbjct: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ Sbjct: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXX 600 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQT Sbjct: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTVAGVA 600 Query: 601 XXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ 660 ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ Sbjct: 601 RVAVAAGESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ 660 Query: 661 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA 720 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA Sbjct: 661 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA 720 Query: 721 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 780 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA Sbjct: 721 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 780 Query: 781 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL 840 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL Sbjct: 781 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL 840 Query: 841 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW 900 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW Sbjct: 841 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW 900 Query: 901 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG 960 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG Sbjct: 901 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG 960 Query: 961 SDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDN 1020 SDPTIGFNYLGRLGAGAGELSEELWRIDQ VPMPLMHTVELNAGTIDTDN Sbjct: 961 SDPTIGFNYLGRLGAGAGELSEELWRIDQDSLALSDAASAVPMPLMHTVELNAGTIDTDN 1020 Query: 1021 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI 1080 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI Sbjct: 1021 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI 1080 Query: 1081 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHT 1140 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHT Sbjct: 1081 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHT 1140 Query: 1141 VVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCD 1200 VVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCD Sbjct: 1141 VVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCD 1200 Query: 1201 LLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNF 1260 LLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNF Sbjct: 1201 LLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNF 1260 Query: 1261 VNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGELARSQ 1320 VNWL WREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGELARSQ Sbjct: 1261 VNWLATQDATAAKAAWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGELARSQ 1320 Query: 1321 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSA 1380 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSA Sbjct: 1321 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSA 1380 Query: 1381 DTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQE 1440 DTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQE Sbjct: 1381 DTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQE 1440 Query: 1441 LAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP 1500 LAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP Sbjct: 1441 LAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP 1500 Query: 1501 ARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES 1560 ARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES Sbjct: 1501 ARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES 1560 Query: 1561 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP 1620 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP Sbjct: 1561 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP 1620 Query: 1621 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYM 1680 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYM Sbjct: 1621 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYM 1680 Query: 1681 IYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLH 1740 IYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLH Sbjct: 1681 IYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLH 1740 Query: 1741 GGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTE 1800 GGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTE Sbjct: 1741 GGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTE 1800 Query: 1801 VVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPP 1860 VVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPP Sbjct: 1801 VVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPP 1860 Query: 1861 GVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGR 1920 GVVGELYLA LTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGR Sbjct: 1861 GVVGELYLAGRGVGVGYVGRSGLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGR 1920 Query: 1921 ADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSE 1980 ADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSE Sbjct: 1921 ADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSE 1980 Query: 1981 LTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFA 2040 LTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFA Sbjct: 1981 LTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFA 2040 Query: 2041 HVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD 2100 HVLGVER AMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD Sbjct: 2041 HVLGVERIGLDDSFFDLGGDSISAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD 2100 Query: 2101 AGERTDRVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXXXXXXXXGAVQTVLLTGATG 2160 AGERTDRVSFAAVHGSDVTEVHARDLTLDKFI GAVQTVLLTGATG Sbjct: 2101 AGERTDRVSFAAVHGSDVTEVHARDLTLDKFIDAPTLRTATTLPRPDGAVQTVLLTGATG 2160 Query: 2161 FLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDTDPLLRKHFNELATERLQ 2220 FLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDTDPLLRKHFNELATERLQ Sbjct: 2161 FLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDTDPLLRKHFNELATERLQ 2220 Query: 2221 VVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRFAL 2280 VVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRFAL Sbjct: 2221 VVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRFAL 2280 Query: 2281 TSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLLRE 2340 TSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLLRE Sbjct: 2281 TSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLLRE 2340 Query: 2341 AHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGERQ 2400 AHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGERQ Sbjct: 2341 AHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGERQ 2400 Query: 2401 RAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLIEA 2460 RAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLIEA Sbjct: 2401 RAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLIEA 2460 Query: 2461 GYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFAPA 2520 GYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFAPA Sbjct: 2461 GYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFAPA 2520 Query: 2521 DRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 DRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL Sbjct: 2521 DRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 >tr|Q9RLP6|Q9RLP6_MYCSM Tax_Id=1772 (mps)SubName: Full=Peptide synthetase;[Mycobacterium smegmatis] Length = 5990 Score = 4856 bits (12595), Expect = 0.0 Identities = 2464/2559 (96%), Positives = 2464/2559 (96%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL Sbjct: 3432 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 3491 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP Sbjct: 3492 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 3551 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP Sbjct: 3552 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 3611 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI Sbjct: 3612 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 3671 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG Sbjct: 3672 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 3731 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPL LFVLDKW Sbjct: 3732 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLTAGTGVAPIGAPVPGAALFVLDKW 3791 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ Sbjct: 3792 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 3851 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP Sbjct: 3852 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 3911 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ Sbjct: 3912 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 3971 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXX 600 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQT Sbjct: 3972 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTVAGVA 4031 Query: 601 XXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ 660 ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ Sbjct: 4032 RVAVAAGESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ 4091 Query: 661 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA 720 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA Sbjct: 4092 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA 4151 Query: 721 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 780 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA Sbjct: 4152 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 4211 Query: 781 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL 840 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL Sbjct: 4212 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL 4271 Query: 841 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW 900 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW Sbjct: 4272 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW 4331 Query: 901 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG 960 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG Sbjct: 4332 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG 4391 Query: 961 SDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDN 1020 SDPTIGFNYLGRLGAGAGELSEELWRIDQ VPMPLMHTVELNAGTIDTDN Sbjct: 4392 SDPTIGFNYLGRLGAGAGELSEELWRIDQDSLALSDAASAVPMPLMHTVELNAGTIDTDN 4451 Query: 1021 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI 1080 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI Sbjct: 4452 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI 4511 Query: 1081 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHT 1140 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHT Sbjct: 4512 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHT 4571 Query: 1141 VVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCD 1200 VVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCD Sbjct: 4572 VVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCD 4631 Query: 1201 LLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNF 1260 LLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNF Sbjct: 4632 LLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNF 4691 Query: 1261 VNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGELARSQ 1320 VNWL WREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGELARSQ Sbjct: 4692 VNWLATQDATAAKAAWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGELARSQ 4751 Query: 1321 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSA 1380 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSA Sbjct: 4752 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSA 4811 Query: 1381 DTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQE 1440 DTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQE Sbjct: 4812 DTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQE 4871 Query: 1441 LAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP 1500 LAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP Sbjct: 4872 LAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP 4931 Query: 1501 ARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES 1560 ARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES Sbjct: 4932 ARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES 4991 Query: 1561 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP 1620 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP Sbjct: 4992 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP 5051 Query: 1621 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYM 1680 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYM Sbjct: 5052 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYM 5111 Query: 1681 IYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLH 1740 IYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLH Sbjct: 5112 IYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLH 5171 Query: 1741 GGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTE 1800 GGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTE Sbjct: 5172 GGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTE 5231 Query: 1801 VVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPP 1860 VVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPP Sbjct: 5232 VVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPP 5291 Query: 1861 GVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGR 1920 GVVGELYLA LTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGR Sbjct: 5292 GVVGELYLAGRGVGVGYVGRSGLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGR 5351 Query: 1921 ADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSE 1980 ADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSE Sbjct: 5352 ADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSE 5411 Query: 1981 LTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFA 2040 LTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFA Sbjct: 5412 LTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFA 5471 Query: 2041 HVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD 2100 HVLGVER AMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD Sbjct: 5472 HVLGVERIGLDDSFFDLGGDSISAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD 5531 Query: 2101 AGERTDRVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXXXXXXXXGAVQTVLLTGATG 2160 AGERTDRVSFAAVHGSDVTEVHARDLTLDKFI GAVQTVLLTGATG Sbjct: 5532 AGERTDRVSFAAVHGSDVTEVHARDLTLDKFIDAPTLRTATTLPRPDGAVQTVLLTGATG 5591 Query: 2161 FLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDTDPLLRKHFNELATERLQ 2220 FLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDTDPLLRKHFNELATERLQ Sbjct: 5592 FLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDTDPLLRKHFNELATERLQ 5651 Query: 2221 VVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRFAL 2280 VVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRFAL Sbjct: 5652 VVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRFAL 5711 Query: 2281 TSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLLRE 2340 TSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLLRE Sbjct: 5712 TSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLLRE 5771 Query: 2341 AHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGERQ 2400 AHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGERQ Sbjct: 5772 AHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGERQ 5831 Query: 2401 RAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLIEA 2460 RAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLIEA Sbjct: 5832 RAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLIEA 5891 Query: 2461 GYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFAPA 2520 GYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFAPA Sbjct: 5892 GYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFAPA 5951 Query: 2521 DRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 DRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL Sbjct: 5952 DRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 5990 Score = 2646 bits (6858), Expect = 0.0 Identities = 1353/2127 (63%), Positives = 1597/2127 (75%), Gaps = 34/2127 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P+ L + LL E E D++ GN + L++ P V+IP FA +V APDA AL Sbjct: 420 MAADPAM-PLAAVRLLAESESDRLATIGNHSALSESAPDAVSIPERFAARVAEAPDAAAL 478 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 R+ TYRELDEA+NR AH L G PG+ VA + PR+ ++++IL K GAAY+P Sbjct: 479 TFEGRTLTYRELDEAANRFAHALLARGIGPGSRVALMSPRTDRSVIAILGAFKAGAAYVP 538 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDPA P AR+ F++ DA PVA +TTA+LRSR D +DLAVID+ DPAI P+ A+S PRP Sbjct: 539 VDPAVPAARVRFILDDASPVAVVTTAELRSRFDGHDLAVIDIDDPAIASLPATAVSDPRP 598 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH N+T L++ L LP PG VW HSL FD SVWEI Sbjct: 599 DDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVLEERLPK-PG-VWPLCHSLAFDASVWEI 656 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 ALL GGRLVVVPE+V SP+D H+LL+ E+V+ L QTPSA MLSP+GLES TL V G Sbjct: 657 SNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQVTFLTQTPSAVAMLSPDGLESMTLAVVG 716 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP LVDRWA R MINAYGPTE TI S PL LFVLD W Sbjct: 717 EACPPALVDRWATNRTMINAYGPTETTICVTSSSPLEPGSVVVPIGSALPRTALFVLDPW 776 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GV GELYVAG GV GYIGR LTASRFV CPFGE G RMYRTGDLVRWG DGQ Sbjct: 777 LRPVPTGVAGELYVAGDGVTCGYIGRSGLTASRFVPCPFGEPGARMYRTGDLVRWGRDGQ 836 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 LEYLGRADEQVKIRGYRIELGE+Q+ALA LDGV+ A I REDRPGD+RLVGYITGTADP Sbjct: 837 LEYLGRADEQVKIRGYRIELGEVQSALAALDGVESAAAIMREDRPGDRRLVGYITGTADP 896 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 +R LA+ LP YMVPTA+VVL +PLT + KLD RALPAPEY +A +YRAPS P E+ Sbjct: 897 VDIRAELADRLPPYMVPTAIVVLPALPLTSSNKLDTRALPAPEYANAEKNYRAPSNPVEE 956 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXX 600 +LAD+YAQVLGVER+GVDDSFFDLGGDSILSMQVVARARAAGIQCRPRD+FVEQT Sbjct: 957 VLADIYAQVLGVERIGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDVFVEQTVARLA 1016 Query: 601 XXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ 660 E VVD+G G TPI+ WLRE G T +FNQT++ QAP GVTE DVV +LQ Sbjct: 1017 SVATVATEIGVVDDGTGSAAPTPIIHWLREAGGATDEFNQTLVVQAPTGVTEPDVVAVLQ 1076 Query: 661 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA 720 ALLDRHATLRLRV+D+ EWSLLVP+A V AR+CL VD L+DDV++ AR +L+PA Sbjct: 1077 ALLDRHATLRLRVQDSD---GEWSLLVPDAATVDARDCLSVVDTLSDDVVLAARAKLNPA 1133 Query: 721 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 780 AGAMVSA+WVR+TSQLVL+IHHLAVDGVSWRILLEDLNIAWAQH +GQ ++LPAGGTSF Sbjct: 1134 AGAMVSALWVRQTSQLVLIIHHLAVDGVSWRILLEDLNIAWAQHHSGQQVQLPAGGTSFL 1193 Query: 781 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL 840 RWS LA+HA T V ADAWR + + P ALP VQPDTDT+ +AG+ SA+LD ETTRQL Sbjct: 1194 RWSKRLADHAHTAEVTAQADAWREILAKPAALPAVQPDTDTHASAGRFSATLDPETTRQL 1253 Query: 841 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW 900 LGEVPAAF AGVQDILLVAFGLAW EFLNRS TPI VDVEGHGR++ELASD+DLSRTVGW Sbjct: 1254 LGEVPAAFHAGVQDILLVAFGLAWAEFLNRSGTPITVDVEGHGRHEELASDIDLSRTVGW 1313 Query: 901 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG 960 FTTKYPVALTV ++PW QVVAG+A LG +VK VKEQLR++P+GLTYGLLRYLN EV+LGG Sbjct: 1314 FTTKYPVALTVADVPWAQVVAGEATLGAVVKDVKEQLRAVPDGLTYGLLRYLNSEVELGG 1373 Query: 961 SDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDN 1020 ++PTIGFNYLGRLGAGAGELSEELWRI+Q VPMPL HTVELNAGT+DTD Sbjct: 1374 TEPTIGFNYLGRLGAGAGELSEELWRIEQGSLALTDVVSAVPMPLAHTVELNAGTMDTDK 1433 Query: 1021 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI 1080 GPSL+ASWTWAPS FDE++A RLS+LWFEALAGICAHV+ GGGGLTPSD+APARLTQR+I Sbjct: 1434 GPSLQASWTWAPSVFDEDKAARLSQLWFEALAGICAHVQAGGGGLTPSDIAPARLTQREI 1493 Query: 1081 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIG--------DDVYAVQLDITITGVLDQH 1132 D+L+ +++V DVLPLTP+QQGLLF + FA G DDVYAVQL IT++G LD Sbjct: 1494 DQLTTQFEVADVLPLTPLQQGLLFQAGFAEAAGAEAAGVPSDDVYAVQLGITLSGSLDPQ 1553 Query: 1133 RLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCA 1192 +LRDAV V+ RHPNLAARFVEQFGEPVQVL+ DP I W++++ D D +E+LCA Sbjct: 1554 QLRDAVQAVIRRHPNLAARFVEQFGEPVQVLSVDPEIGWQFVEFDSGDTGVDERVERLCA 1613 Query: 1193 AERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLP 1252 AERSAVC L E+P FRAALIRT+ N HRFVLT HHIVIDGWSLP+LLQEIFA YF LP Sbjct: 1614 AERSAVCKLGEQPVFRAALIRTADNLHRFVLTIHHIVIDGWSLPVLLQEIFAAYFDQSLP 1673 Query: 1253 AAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRA 1312 +AAPYRNFV WL W VL+GFETPTLVAPP GPRG+ES+R+S TTR Sbjct: 1674 SAAPYRNFVTWLGAQDRDAAQAAWGSVLEGFETPTLVAPPAQAGPRGVESFRLSEATTRT 1733 Query: 1313 LGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTV 1372 LGELARSQHTT+NTVLQAAW QLLM MTGQRDV FGTAVSGRP DLAGA+SMVGLLINTV Sbjct: 1734 LGELARSQHTTVNTVLQAAWAQLLMWMTGQRDVVFGTAVSGRPVDLAGADSMVGLLINTV 1793 Query: 1373 PIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDT 1432 P+RA TTV DLL QLQ HNDT++HEH+ALN+IH ++GH++LFDTLF+YE+YPID Sbjct: 1794 PVRATSGVATTVTDLLGQLQRDHNDTVDHEHMALNEIHRLTGHDRLFDTLFVYENYPIDA 1853 Query: 1433 SAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRL 1492 +A + VQ+LAVT+F +REYNHYPLS++A PGHE+ LRVE+DT +FD + IE L+DR +R+ Sbjct: 1854 NALLSVQDLAVTDFASREYNHYPLSMVATPGHEVVLRVEFDTEIFDAASIEALVDRLRRV 1913 Query: 1493 LEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAP 1552 L+AM DP RRLS++D++D E +LDEW NRAVLT+P + +SIP FA V R P+A Sbjct: 1914 LDAMATDPGRRLSTIDLLDPQEHDRLDEWGNRAVLTRPAPALESIPASFAESVRRVPDAV 1973 Query: 1553 AVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAY 1612 A++ S Y ELDEA+N++A+LLA GA PG+ VA+++PR+ +A+V ILA+LKTGAAY Sbjct: 1974 ALSCGDRSWTYRELDEASNRMAHLLAGRGAKPGERVAMLLPRTGEAVVTILAILKTGAAY 2033 Query: 1613 LPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTP 1672 LPIDP+ P AR+EF+L DA PVAAV++ DL +R + V+EVDDPA+ ST+L P Sbjct: 2034 LPIDPAHPDARIEFVLKDAAPVAAVSSADLCTRLIASGVPVIEVDDPAIGAEASTSLPVP 2093 Query: 1673 SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVW 1732 + DDIAY+IYTSGTTG PKGVA+TH NV Q+LDTL A+L G W+Q HSL FD SVW Sbjct: 2094 AVDDIAYIIYTSGTTGTPKGVAVTHRNVAQLLDTLGAQLEL--GQTWTQCHSLAFDYSVW 2151 Query: 1733 EIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSP---------E 1783 EIWG LL+GGRL++VP+++ SP+DLHA+LV+E V++L QTPSA + E Sbjct: 2152 EIWGPLLNGGRLLMVPDAVVRSPEDLHAMLVAEQVSMLSQTPSAFYALQTADALYPERGE 2211 Query: 1784 GLEGTALVVAGEACPTEVVDRW-----AVDRVMINAYGPTESTIYAAIS--APLSPGSDV 1836 L+ +V GEA + W + R MIN YG TE+T++A+ + Sbjct: 2212 QLKLQTVVFGGEALEPHRLSGWMHAHPGMPR-MINMYGITETTVHASFREIGEADLANST 2270 Query: 1837 VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEP 1896 PIG P+ + FVLD WLR VP GVVGELY+A LT TRFVACPFG P Sbjct: 2271 SPIGVPLEHLSFFVLDGWLRQVPVGVVGELYVAGEGLACGYISRSDLTSTRFVACPFGAP 2330 Query: 1897 GARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARE 1956 GARMYRTGDLVRWG DGQLQY+GRADEQVKIRGYRIELGE+ AAL +DGV+QA VIARE Sbjct: 2331 GARMYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVIARE 2390 Query: 1957 DRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAP 2016 DRPGDKRLVGY+TG DP AR+ L R+PAYMVPAA+V +E+LPLTVNGKL+ RALPAP Sbjct: 2391 DRPGDKRLVGYVTGAVDPVKARAALAERIPAYMVPAAIVVMESLPLTVNGKLNTRALPAP 2450 Query: 2017 EYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALD 2076 EYQ A +YRAP E+ L GI+A VLGVER +M+V A A Sbjct: 2451 EYQDADQYRAPANAVEELLTGIYAQVLGVERVGVDDSFFDLGGDSISSMQVVARARAA-G 2509 Query: 2077 ADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 R +F TV++L+ V GE Sbjct: 2510 LVCRPRDIFVEQTVSRLAQVVTLADGE 2536 Score = 2610 bits (6764), Expect = 0.0 Identities = 1343/2136 (62%), Positives = 1603/2136 (75%), Gaps = 46/2136 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M +P R L + DLLD EHD+++ WGNRAVLT P P +IPA FAE V R PDAVAL Sbjct: 1917 MATDPGRR-LSTIDLLDPQEHDRLDEWGNRAVLTRPAPALESIPASFAESVRRVPDAVAL 1975 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 GDRSWTYRELDEASNR+AH+LA GAKPG VA L+PR+GEA+++IL++LKTGAAYLP Sbjct: 1976 SCGDRSWTYRELDEASNRMAHLLAGRGAKPGERVAMLLPRTGEAVVTILAILKTGAAYLP 2035 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAHPDARI F++ DA PVAA+++ADL +RL + VI++ DPAI S +L P Sbjct: 2036 IDPAHPDARIEFVLKDAAPVAAVSSADLCTRLIASGVPVIEVDDPAIGAEASTSLPVPAV 2095 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH NV QL+ L A L G Q W+Q HSL FD SVWEI Sbjct: 2096 DDIAYIIYTSGTTGTPKGVAVTHRNVAQLLDTLGAQLELG--QTWTQCHSLAFDYSVWEI 2153 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPEG---L 291 WG LL+GGRL++VP++V SP+DLH +L+ E+VS+L QTPSA A L PE L Sbjct: 2154 WGPLLNGGRLLMVPDAVVRSPEDLHAMLVAEQVSMLSQTPSAFYALQTADALYPERGEQL 2213 Query: 292 ESTTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSE--PLXXXXXXXXX 345 + T++ GEA + W PG MIN YG TE T++A+ E Sbjct: 2214 KLQTVVFGGEALEPHRLSGWMHAHPGMPRMINMYGITETTVHASFREIGEADLANSTSPI 2273 Query: 346 XXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 FVLD WLR P GVVGELYVAG G+A GYI R DLT++RFVACPFG G R Sbjct: 2274 GVPLEHLSFFVLDGWLRQVPVGVVGELYVAGEGLACGYISRSDLTSTRFVACPFGAPGAR 2333 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLVRWG+DGQL+Y+GRADEQVKIRGYRIELGE+ AAL LDGV+QA VIAREDRP Sbjct: 2334 MYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVIAREDRP 2393 Query: 466 GDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 GDKRLVGY+TG DP + R ALAE +PAYMVP A+VV++++PLTVNGKL+ RALPAPEY+ Sbjct: 2394 GDKRLVGYVTGAVDPVKARAALAERIPAYMVPAAIVVMESLPLTVNGKLNTRALPAPEYQ 2453 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQC 585 A + YRAP+ E++L +YAQVLGVERVGVDDSFFDLGGDSI SMQVVARARAAG+ C Sbjct: 2454 DA-DQYRAPANAVEELLTGIYAQVLGVERVGVDDSFFDLGGDSISSMQVVARARAAGLVC 2512 Query: 586 RPRDIFVEQTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVIT 644 RPRDIFVEQT ES V D GVGPVVATPIMRWL +DGP +FNQTV+ Sbjct: 2513 RPRDIFVEQTVSRLAQVVTLADGESGVADTGVGPVVATPIMRWLYSLDGPIDEFNQTVVL 2572 Query: 645 QAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA 704 Q PA VTE DV+ +LQA+LD HA LRLRV D + L VPE G+V A +CL TV Sbjct: 2573 QVPAEVTEADVIAVLQAVLDHHAMLRLRVADAENG----DLTVPEPGSVDACDCLCTVGE 2628 Query: 705 LTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 LT D L R +L+PA G+M++A WV ET QL LMIHHLAVD VSWRILLEDLNIAWAQH Sbjct: 2629 LTADTLAAVRAQLNPATGSMLTAAWVPETRQLALMIHHLAVDAVSWRILLEDLNIAWAQH 2688 Query: 765 CTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVT 824 +GQ + LP GTSF RWS LL +HA+T V AD WR V + P ALP QPDTD Y Sbjct: 2689 RSGQPVVLPTPGTSFGRWSRLLDQHARTADVLATADVWRTVAAAPAALPAPQPDTDVYAN 2748 Query: 825 AGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGR 884 AGQLSASLDVETT QLLG+VPAAF AGVQDILL+AFGLAW+E+L IG+DVEGHGR Sbjct: 2749 AGQLSASLDVETTGQLLGDVPAAFHAGVQDILLIAFGLAWSEYLGSEQGSIGIDVEGHGR 2808 Query: 885 YDELASDVDLSRTVGWFTTKYPVALTVE----NLPWEQVVAGDAALGGIVKAVKEQLRSL 940 +EL D DLSRTVGWFT+KYPVAL + + WEQVV GDAALG ++K KEQLRS+ Sbjct: 2809 TEELFGDADLSRTVGWFTSKYPVALDFDRNTGGISWEQVVNGDAALGAVIKKAKEQLRSV 2868 Query: 941 PEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXX 1000 P+GLTYGLLRYLNP+V+L DPTIGFNYLGRLGAGA +LS++LWR+D Sbjct: 2869 PDGLTYGLLRYLNPDVELDNPDPTIGFNYLGRLGAGAADLSDDLWRLDPDAVSLTAAGGR 2928 Query: 1001 VPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRG 1060 V PL HTVELNAGT+DT+ GP L+A+WTWAPSA DEEQ ++S+LW +ALAGICAHVR Sbjct: 2929 VNTPLGHTVELNAGTMDTEAGPQLQATWTWAPSALDEEQIQKVSKLWSDALAGICAHVRS 2988 Query: 1061 GGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQ 1120 GGGGLTPSDVAPARL+Q+QID+L+ ++D+ DVLPLTP+Q GLLFH+ ++ +D+YAVQ Sbjct: 2989 GGGGLTPSDVAPARLSQQQIDDLTAQFDMVDVLPLTPLQHGLLFHTGLSQD-SEDLYAVQ 3047 Query: 1121 LDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRG-D 1179 LDI+++G LD R+RDAV TV+ R PN+ A F E FGEPVQ+L A+P +AW+Y+DL G Sbjct: 3048 LDISVSGRLDVERMRDAVQTVITRRPNVVAHFYEDFGEPVQILPANPELAWQYVDLSGRS 3107 Query: 1180 DLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILL 1239 D+ D +I Q+ AAER+AVC L ++P FRAA++RT +RFVLT HHIV+DGWS PILL Sbjct: 3108 DI--DAQIAQISAAERAAVCRLGDQPPFRAAVLRTGEETYRFVLTNHHIVLDGWSKPILL 3165 Query: 1240 QEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVP-GPR 1298 QEIF YFG RLPA PYR FV+WL WR V GFETPTLV PG+ G R Sbjct: 3166 QEIFVSYFGQRLPAPVPYRRFVSWLAEQDNDAARAAWRGVFSGFETPTLVGTPGLALGRR 3225 Query: 1299 GIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADL 1358 +ES++VSAETT+ALGELARS HTT++TVLQ AW Q+LM +TGQ DVAFGTAVSGRP D+ Sbjct: 3226 AVESFQVSAETTQALGELARSCHTTVSTVLQGAWAQVLMWLTGQPDVAFGTAVSGRPTDV 3285 Query: 1359 AGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQL 1418 GA+SMVGLLINTVP+RA ++ +TTV L+ QLQ + DTL+H+HLALN+IH +GH+QL Sbjct: 3286 PGADSMVGLLINTVPVRATITPETTVASLMNQLQGAYTDTLDHQHLALNEIHRATGHDQL 3345 Query: 1419 FDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFD 1478 FDT+F+YE+YPIDT+A +GVQEL++T+F NREYNHYPLSV A+PGHELGLRVEYDT+VFD Sbjct: 3346 FDTVFVYENYPIDTAALLGVQELSITDFTNREYNHYPLSVQAVPGHELGLRVEYDTNVFD 3405 Query: 1479 VSEIETLIDRFQRLL---------EAMIDDPA-RRLSSMDVVDDDERTQLDEWANRAVLT 1528 I+ L++R QR+L E M +P+ R L S D++D+DE Q++ W NRAVLT Sbjct: 3406 RQRIKRLVNRLQRVLVAIDRGYEGEVMTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLT 3465 Query: 1529 QPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSV 1588 P +P +IP +FA QV R P+A A+ S Y ELDEA+N+LA++LA +GA PG +V Sbjct: 3466 DPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATV 3525 Query: 1589 ALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDG 1648 A ++PRS +AI++IL+VLKTGAAYLP+DP+ P AR+ FM+ DAKPVAA+TT DLRSR D Sbjct: 3526 AFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQ 3585 Query: 1649 FDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLP 1708 +DL V+++ DPA++ PS L P PDD+AYM YTSGTTGVPK VA+TH NVTQ++ L Sbjct: 3586 YDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALH 3645 Query: 1709 AELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVN 1768 A+LP+GPG VWSQWHSLVFDVSVWEIWGALLHGGRLV+VPES+ SPDDLH LL++E V+ Sbjct: 3646 ADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVS 3705 Query: 1769 VLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISA 1828 VL QTPSA M+SPEGLE T L+VAGEACPTE+VDRWA RVMINAYGPTE+TIYAA+S Sbjct: 3706 VLCQTPSAAGMLSPEGLESTTLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSE 3765 Query: 1829 PLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRF 1888 PL+ G+ V PIG+PVP A FVLD+WLRP P GVVGELY+A LT +RF Sbjct: 3766 PLTAGTGVAPIGAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRF 3825 Query: 1889 VACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVD 1948 VACPFGE G RMYRTGDLVRWG DGQL+YLGRADEQVKIRGYRIELGEIQAAL+ +DGVD Sbjct: 3826 VACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVD 3885 Query: 1949 QAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKL 2008 QAVVIAREDRPGDKRLVGYITGTADPA R+ L LPAYMVP AVV L+T+PLTVNGKL Sbjct: 3886 QAVVIAREDRPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKL 3945 Query: 2009 DRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRV 2067 DRRALPAPEY+SA YRAP T E+ LA ++A VLGVER +M+V Sbjct: 3946 DRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQV 4005 Query: 2068 TAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 A A R +F TVA ++ V AGE Sbjct: 4006 VARARAA-GIQCRPRDIFVEQTVAGVA-RVAVAAGE 4039 Score = 696 bits (1795), Expect = 0.0 Identities = 426/988 (43%), Positives = 552/988 (55%), Gaps = 27/988 (2%) Query: 1125 ITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD 1184 I GV+D L+ A+ + A F E G+ Q + D+R D P+ Sbjct: 38 IDGVVDHGLLQQAIRQALQEAEPARATFFEADGQVFQKPLDYSELEVPLYDVRDAD-DPE 96 Query: 1185 HEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFA 1244 + ++ A + L R + AL +T Q HHI +DG + ++ + I Sbjct: 97 AKAREMAAEIQHTPLPLTGR-LVKFALFQTRDEQFYLFGLGHHISVDGLGMALVSRRIST 155 Query: 1245 GYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG-------VPGP 1297 Y P F + + D + PP P P Sbjct: 156 IYTSLVTGKPVPEAYFGSLRDLVECEMSYESSADYQDDLAYWSENLPPDTGLDQGLAPTP 215 Query: 1298 RGIESYRVSAET------TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRD-VAFGTA 1350 G +Y SA + EL+++ +V AA L + D VA Sbjct: 216 HGKNAYTPSASVPMDPAIVGRIKELSKTLRIRRYSVTTAACALLAQSWSSTGDQVALDFP 275 Query: 1351 VSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHL---ALN 1407 VS R + ++++ +L P+ TVG+ + + + L+H+ L Sbjct: 276 VSRRVS--PESKTLPAMLAGVAPLVLDAPPQLTVGEFCKHVDIRIRELLQHQRFPVHRLG 333 Query: 1408 DIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELG 1467 D + G Q + L + T F G E + N+ H+ L + G EL Sbjct: 334 DGGALRGPRQASNRLAVNFIPSRLTLDFAGA-EATASYTNHGPMGHFGLFFIG-AGEELF 391 Query: 1468 LRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 L F E+ L +R ++ AM DPA L+++ ++ + E +L N + L Sbjct: 392 LSTAGAGQPFANFEVPELAERLGAIVAAMAADPAMPLAAVRLLAESESDRLATIGNHSAL 451 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 ++ SIPE FA +V P+A A+TFEG +L Y ELDEAAN+ A+ L G PG Sbjct: 452 SESAPDAVSIPERFAARVAEAPDAAALTFEGRTLTYRELDEAANRFAHALLARGIGPGSR 511 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VALM PR+ +++AIL K GAAY+P+DP+VPAAR+ F+L DA PVA VTT +LRSRFD Sbjct: 512 VALMSPRTDRSVIAILGAFKAGAAYVPVDPAVPAARVRFILDDASPVAVVTTAELRSRFD 571 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 G DL V+++DDPA+ P+T + P PDDIAY+IYTSGTTG PKGVA+TH N+T ++ L Sbjct: 572 GHDLAVIDIDDPAIASLPATAVSDPRPDDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVL 631 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 LP PG VW HSL FD SVWEI ALL GGRLV+VPE++AGSP+D H LLV+E V Sbjct: 632 EERLPK-PG-VWPLCHSLAFDASVWEISNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQV 689 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAIS 1827 L QTPSAV M+SP+GLE L V GEACP +VDRWA +R MINAYGPTE+TI S Sbjct: 690 TFLTQTPSAVAMLSPDGLESMTLAVVGEACPPALVDRWATNRTMINAYGPTETTICVTSS 749 Query: 1828 APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTR 1887 +PL PGS VVPIGS +P+ A FVLD WLRPVP GV GELY+A LT +R Sbjct: 750 SPLEPGSVVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVTCGYIGRSGLTASR 809 Query: 1888 FVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGV 1947 FV CPFGEPGARMYRTGDLVRWG DGQL+YLGRADEQVKIRGYRIELGE+Q+AL+ +DGV Sbjct: 810 FVPCPFGEPGARMYRTGDLVRWGRDGQLEYLGRADEQVKIRGYRIELGEVQSALAALDGV 869 Query: 1948 DQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGK 2007 + A I REDRPGD+RLVGYITGTADP R+EL +RLP YMVP A+V L LPLT + K Sbjct: 870 ESAAAIMREDRPGDRRLVGYITGTADPVDIRAELADRLPPYMVPTAIVVLPALPLTSSNK 929 Query: 2008 LDRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMR 2066 LD RALPAPEY +A++ YRAP E+ LA I+A VLGVER +M+ Sbjct: 930 LDTRALPAPEYANAEKNYRAPSNPVEEVLADIYAQVLGVERIGVDDSFFDLGGDSILSMQ 989 Query: 2067 VTAAVNTALDADLSVRTLFEAPTVAKLS 2094 V A A R +F TVA+L+ Sbjct: 990 VVARARAA-GIQCRPRDVFVEQTVARLA 1016 >tr|A5A9R5|A5A9R5_MYCCH Tax_Id=1774 (mps2)SubName: Full=MPS2 protein;[Mycobacterium chelonae] Length = 2576 Score = 3573 bits (9264), Expect = 0.0 Identities = 1812/2579 (70%), Positives = 2062/2579 (79%), Gaps = 23/2579 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M+A+P TRTLLS DLLD+D+HD+++ WGNRAVLT+P PV IP LFA QV RAP+ VAL Sbjct: 1 MSADP-TRTLLSMDLLDDDDHDRLDEWGNRAVLTEPTAEPVAIPVLFAVQVERAPETVAL 59 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V GDRSWTYR+LD+ +NR+AH+LA +GA PG V L+PRSGEAI+ +L+VLKTGAAYLP Sbjct: 60 VCGDRSWTYRDLDQVTNRIAHLLAGNGAGPGEVVGLLVPRSGEAIIGLLAVLKTGAAYLP 119 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAHPD RI FM+SDA+PVA LTTADL SR D D+ V ++ DP ID +PS AL P P Sbjct: 120 IDPAHPDERIKFMVSDAEPVAVLTTADLNSRFDGLDVRVTEIDDPLIDGQPSSALPAPEP 179 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLV A+ ADLP+GPGQVWSQWHSLVFDVSVWEI Sbjct: 180 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVDAVRADLPAGPGQVWSQWHSLVFDVSVWEI 239 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPES+ SSPD+LH LLI+EKVSVLCQTPSAAGMLSPE LESTTLIVAG Sbjct: 240 WGALLHGGRLVVVPESIASSPDELHELLISEKVSVLCQTPSAAGMLSPERLESTTLIVAG 299 Query: 301 EACPTELVDRWAP-GRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 EACPTELVDRWA GR MINAYGPTEATIYAAMS PL LFVLDK Sbjct: 300 EACPTELVDRWATSGRTMINAYGPTEATIYAAMSGPLRPGSDVAPIGSPVPGAALFVLDK 359 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WLRPAPEGVVGELYVAG+GVA GY R LTASRF+ACPFG G RMYRTGDLV+WG DG Sbjct: 360 WLRPAPEGVVGELYVAGNGVAPGYAHRSGLTASRFLACPFGGPGSRMYRTGDLVQWGEDG 419 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVKIRGYRIELGEIQAALA+LDGV+QAVVIAREDRPGDKRLVGYI G+AD Sbjct: 420 QLQYLGRADEQVKIRGYRIELGEIQAALARLDGVEQAVVIAREDRPGDKRLVGYIMGSAD 479 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 P + RTALAE LPAYMVP AVVVL+T+PLTVNGKLD+RALPAPEYRS DYRAP+ P E Sbjct: 480 PVEARTALAERLPAYMVPAAVVVLETLPLTVNGKLDKRALPAPEYRSVGTDYRAPTGPVE 539 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 +ILAD+YAQVLGV+RVGVD+SFFDLGGDSILSMQVV+RARAAG+ CRPRDIFVEQT Sbjct: 540 KILADIYAQVLGVDRVGVDESFFDLGGDSILSMQVVSRARAAGVVCRPRDIFVEQTVSGV 599 Query: 600 XXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVI 658 +S VVDEG+GPV ATPIM WL V GPT QFNQT++ QAPAGVTEDDVVV+ Sbjct: 600 AAVAVLSDGQSGVVDEGIGPVSATPIMHWLHGVQGPTDQFNQTIVLQAPAGVTEDDVVVV 659 Query: 659 LQALLDRHATLRLRVEDTQE-DTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRL 717 LQALLDRHATLRLR ED+ DTD WSL VPE GAV AR+CLR + L+D LV AR +L Sbjct: 660 LQALLDRHATLRLRAEDSDAPDTDVWSLTVPEKGAVNARDCLRVAETLSDAELVAARAQL 719 Query: 718 DPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGT 777 +PA GA +SAVWV ET QL LMIHHLAVDGVSWRILLEDLNIAWAQH GQ +ELP GGT Sbjct: 720 NPATGAELSAVWVPETRQLALMIHHLAVDGVSWRILLEDLNIAWAQHHGGQPVELPTGGT 779 Query: 778 SFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETT 837 SFARWS+LL EHA + V AD WR VT+VP LP V P+ DTY TA LS SLD ETT Sbjct: 780 SFARWSSLLNEHAHSAEVLATADTWREVTAVPAPLPAVLPELDTYATAKTLSVSLDAETT 839 Query: 838 RQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRT 897 R+LL EVPAAF AGVQDILL+AFGLAW EFL+ + +G+ VEGHGR++ELA DVDLSRT Sbjct: 840 RELLSEVPAAFHAGVQDILLIAFGLAWNEFLDSNVASVGIGVEGHGRHEELADDVDLSRT 899 Query: 898 VGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVD 957 VGWFTTKYPVAL+V L W++V G A LG IVK KEQLR+LP+ LTYGLLRYLN +VD Sbjct: 900 VGWFTTKYPVALSVRGLSWQEVAGGAAELGPIVKGAKEQLRALPDPLTYGLLRYLNRDVD 959 Query: 958 LGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTID 1017 L +P IGFNYLGRLGAGA +L ++LWRI++ V MPLM+TV+LNAG ++ Sbjct: 960 LAAPEPVIGFNYLGRLGAGAADLGDDLWRINEDSLTSTSVASSVSMPLMYTVDLNAGIVE 1019 Query: 1018 ----TDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPA 1073 ++G LRA WTWAPS+ E Q RLS+LWFEALAGICA+VR GGGGLTPSD+APA Sbjct: 1020 GGLGDESGAHLRAGWTWAPSSVTEPQVQRLSQLWFEALAGICAYVRNGGGGLTPSDIAPA 1079 Query: 1074 RLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGD--------DVYAVQLDITI 1125 +L+Q+QIDEL +++++ DVLPLTP+QQGLLFH+TFAR G D YAVQLDIT+ Sbjct: 1080 QLSQQQIDELHEQHNIVDVLPLTPIQQGLLFHTTFARAAGVLEDEAAGVDFYAVQLDITV 1139 Query: 1126 TGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDH 1185 TG++DQ RLRDAVH+VV RHPNLAARF QFG+PVQV+ ADP+IAWRYLDLRGDDLTPD Sbjct: 1140 TGLVDQLRLRDAVHSVVRRHPNLAARFCTQFGDPVQVILADPVIAWRYLDLRGDDLTPDE 1199 Query: 1186 EIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAG 1245 EI++LCAAER+AVCDL +RPT RAALIRT GN+HRFVLTFHH+VIDGWSLPILLQEIFA Sbjct: 1200 EIQRLCAAERAAVCDLADRPTLRAALIRTQGNKHRFVLTFHHVVIDGWSLPILLQEIFAS 1259 Query: 1246 YFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRV 1305 YFGHRLPA + YRNFV+WL W VL+GF+TPTLVAPP PG RGIESYRV Sbjct: 1260 YFGHRLPAPSSYRNFVSWLAEQDRDAARSAWGTVLEGFDTPTLVAPPAPPGARGIESYRV 1319 Query: 1306 SAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMV 1365 SAETT+AL +LARSQHTTI+TVLQAAW QLLM +TGQ DVAFGTAVSGRPA+LAG++S+V Sbjct: 1320 SAETTQALADLARSQHTTISTVLQAAWAQLLMVVTGQHDVAFGTAVSGRPAELAGSDSIV 1379 Query: 1366 GLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLY 1425 GLLINTVP+RA+ +A TTV +LL QLQS HNDT+EHEHLALN+IHH++GHEQLFDTLFLY Sbjct: 1380 GLLINTVPVRARATATTTVSELLAQLQSAHNDTIEHEHLALNEIHHIAGHEQLFDTLFLY 1439 Query: 1426 ESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETL 1485 ESYPIDTSAF GVQELA+TEF REYNHYPLSVMALPGHELG+RVE+DT FD ++IE + Sbjct: 1440 ESYPIDTSAFTGVQELAITEFVTREYNHYPLSVMALPGHELGIRVEFDTDKFDATQIEAV 1499 Query: 1486 IDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQV 1545 +RF+R+L +M+ D ++RLSS+DV+ E QLD W NR VL + + SIPE FA QV Sbjct: 1500 FERFERVLTSMVADASQRLSSLDVLKTSEHQQLDGWGNRKVLARGPEPVLSIPESFAEQV 1559 Query: 1546 ERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAV 1605 PEA A+TFEG S YGELDEAA +LANLLA+YGA PG+SVAL++PRS DAIVAILA+ Sbjct: 1560 NSAPEAVALTFEGRSTTYGELDEAATRLANLLAIYGAGPGESVALLMPRSDDAIVAILAI 1619 Query: 1606 LKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEV----DDPAV 1661 LKTGA+YLPIDPSVP RLEFML DA PVAAVTT +LR+RFDG + VV+ DDP Sbjct: 1620 LKTGASYLPIDPSVPDTRLEFMLSDAVPVAAVTTAELRARFDGSGVSVVQFDDAEDDPTG 1679 Query: 1662 EIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQ 1721 IY T LLTP+PDDIAY IYTSGTTGVPKGVAI H NVTQ L +P GPG VW+Q Sbjct: 1680 AIYGHTPLLTPAPDDIAYTIYTSGTTGVPKGVAIAHSNVTQALKFPLTHMPTGPGEVWTQ 1739 Query: 1722 WHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS 1781 SLVFD++VWEI+GALLHGGRLVIVP+S+ SPDD LL+ E V VL+QTPSAV M+S Sbjct: 1740 AGSLVFDITVWEIFGALLHGGRLVIVPDSVVRSPDDFRDLLIREKVTVLFQTPSAVGMLS 1799 Query: 1782 PEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGS 1841 PEGL+ LVVAGEACPTEVVD+WA RVMIN YGPTE+TIYA L GS VVPIG Sbjct: 1800 PEGLDNMTLVVAGEACPTEVVDKWAPGRVMINGYGPTETTIYATF-GELIAGSGVVPIGV 1858 Query: 1842 PVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMY 1901 PVP A FVLD W+RPVPPGVVGELY+A LT +RF ACPFGEPGARMY Sbjct: 1859 PVPDAALFVLDRWMRPVPPGVVGELYVAGLGVGIGYVGRAALTASRFTACPFGEPGARMY 1918 Query: 1902 RTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGD 1961 RTGDLV WGDDGQLQYLGRADEQVKIRG+RIELGEIQAAL+D+DGV+QA VIAREDRPGD Sbjct: 1919 RTGDLVSWGDDGQLQYLGRADEQVKIRGFRIELGEIQAALADLDGVEQAAVIAREDRPGD 1978 Query: 1962 KRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSA 2021 KRLVGY G +PA RS L RLP YMVPAAVV LE LPLTVNGKLD+RALP PEY Sbjct: 1979 KRLVGYFIGAGEPAQLRSSLAKRLPPYMVPAAVVRLEALPLTVNGKLDKRALPIPEYDDR 2038 Query: 2022 QRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSV 2081 RYRAP TE+ +AGI+A VLGVER AMRV AA+NT+LDA L+V Sbjct: 2039 ARYRAPANATEEAVAGIYAQVLGVERVGTDDSFFDLGGDSISAMRVVAAINTSLDAQLAV 2098 Query: 2082 RTLFEAPTVAKLSLHVEHDAGERTDRVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXX 2141 RTLFE+P+V LS++++ A ++A+VHG EV A DLTLDKFI Sbjct: 2099 RTLFESPSVRSLSVYLDGAASSGVSGPTYASVHGPGALEVRASDLTLDKFIDEATLQAAP 2158 Query: 2142 XXXXXXGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATF 2201 +TVLLTGATGFLGRYL+L+WL++L VD +ICLVR KSDEDARRRL+ TF Sbjct: 2159 ALPRANARPRTVLLTGATGFLGRYLVLQWLKELEDVDGTLICLVRAKSDEDARRRLDKTF 2218 Query: 2202 DT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLP 2260 D+ D L + + LA +RLQV+AGDK +P LGLD++TWQRL+ +VDLIVDSAA VNSVLP Sbjct: 2219 DSGDAELIRVYEALAADRLQVIAGDKAEPGLGLDDETWQRLSGTVDLIVDSAALVNSVLP 2278 Query: 2261 YSELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIE 2320 YSELFGPNVVGTAELIRFALTSKLKP+ FVST+DVGR+IE S F E ADIRL+SA R + Sbjct: 2279 YSELFGPNVVGTAELIRFALTSKLKPYTFVSTADVGREIEKSTFVEDADIRLISAIRPSD 2338 Query: 2321 VGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSI 2380 YANGYGNSKWAGEVLLREAH+ GLPV VFRSGMIMV +YAGQ+N +DTV+RMVLS+ Sbjct: 2339 GSYANGYGNSKWAGEVLLREAHEQVGLPVTVFRSGMIMVGTSYAGQVNASDTVARMVLSV 2398 Query: 2381 VATGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHV 2440 VATGVAP S Y+ D G+RQRAHFDGLPV+FVA+AIT LG Q A S T +GFETYHV Sbjct: 2399 VATGVAPHSVYRLTDEGDRQRAHFDGLPVEFVAEAITTLGGQPAGSST-GAVTGFETYHV 2457 Query: 2441 MNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLL 2500 MNPHDDGIGID Y+DWLIEAG+PIERI DF EW+ RFEA L L D QRQ SVLQML +L Sbjct: 2458 MNPHDDGIGIDEYVDWLIEAGHPIERISDFSEWVARFEAGLHALPDHQRQGSVLQMLKIL 2517 Query: 2501 KQQAGELQPPVPTRGSFAPADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 + + QPP P+RGS APADRFQAAVRDA IG +IP V+ +I KY TDL+L GLL Sbjct: 2518 QDHGWDGQPPDPSRGSMAPADRFQAAVRDAKIGSGHDIPQVSAPIIAKYATDLRLHGLL 2576 >tr|B1MIF0|B1MIF0_MYCA9 Tax_Id=561007 SubName: Full=Probable peptide synthetase NRP;[Mycobacterium abscessus] Length = 2581 Score = 3549 bits (9202), Expect = 0.0 Identities = 1795/2586 (69%), Positives = 2070/2586 (80%), Gaps = 32/2586 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M+A+P TRTLLS DLLD+D+HD+++ WGNRAVLT+P PV+IP +FA QV RAP+ VAL Sbjct: 1 MSADP-TRTLLSMDLLDDDDHDRLDEWGNRAVLTEPAAEPVSIPVVFAVQVERAPETVAL 59 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V DRSWTYRELD+ +NR+AH+LA +GA PG V L+PRSGEAI+ +L++LKTGAAYLP Sbjct: 60 VCRDRSWTYRELDQITNRIAHLLAGNGAGPGEVVGLLVPRSGEAIIGLLAILKTGAAYLP 119 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAHPD RI FM+SDA PVA LTTADL SR + D++VI++ DP ID +PS AL P P Sbjct: 120 IDPAHPDERIKFMVSDAGPVAVLTTADLGSRFEGLDVSVIEIDDPLIDGQPSSALPTPEP 179 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLV A+ ADLP+ PG+VWSQWHSLVFDVSVWEI Sbjct: 180 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVDAVRADLPARPGEVWSQWHSLVFDVSVWEI 239 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPESV SSPDDLH LLI+EKVSVLCQTPSAAGMLSPE LESTTLIVAG Sbjct: 240 WGALLHGGRLVVVPESVASSPDDLHELLISEKVSVLCQTPSAAGMLSPERLESTTLIVAG 299 Query: 301 EACPTELVDRWAP-GRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 EACP ELVDRWA GR MINAYGPTEATIYAAMS PL LFVLDK Sbjct: 300 EACPPELVDRWATSGRTMINAYGPTEATIYAAMSGPLTPGSGVAPIGSPVPGAALFVLDK 359 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WLRPAPEGVVGELYVAG+GVA GY R LTASRF+ACPFG G RMYRTGDLV+WG DG Sbjct: 360 WLRPAPEGVVGELYVAGNGVAPGYAHRSGLTASRFLACPFGGPGSRMYRTGDLVQWGEDG 419 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVKIRGYRIELGEIQAAL++LDGV+QAVVIAREDRPGDKRLVGYI GTAD Sbjct: 420 QLQYLGRADEQVKIRGYRIELGEIQAALSRLDGVEQAVVIAREDRPGDKRLVGYIMGTAD 479 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 P + R ALAE LPAYMVP AVVVLD +PLTVNGKLD+RALPAPEYRS DYRAPS P E Sbjct: 480 PVEARNALAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRSVGTDYRAPSGPVE 539 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 ++LAD+YAQVLGV+RVGVD+SFFDLGGDSILSMQVV+RARAAG+ CRPRDIFVEQT Sbjct: 540 KVLADIYAQVLGVDRVGVDESFFDLGGDSILSMQVVSRARAAGVHCRPRDIFVEQTVSGV 599 Query: 600 XXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVI 658 + +VD+G+GPV+ATPI+ WL+ V GP QFNQT++ QAP GVTEDDVVVI Sbjct: 600 AAVASLSDGRAGIVDDGIGPVLATPIIHWLQGVPGPVDQFNQTIVLQAPVGVTEDDVVVI 659 Query: 659 LQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLD 718 LQALLDRHATLRLR E + + + WSLLVP+ G V AR CLR ++L+D LV AR+RL+ Sbjct: 660 LQALLDRHATLRLRAE-SGDASGGWSLLVPDTGTVDARACLRVAESLSDAELVAARSRLN 718 Query: 719 PAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTS 778 PAAGA +SAVWV ++ QL LMIHHLAVDGVSWRILLEDLNIAWAQH GQ ++LPAGGTS Sbjct: 719 PAAGAQLSAVWVPDSRQLALMIHHLAVDGVSWRILLEDLNIAWAQHHGGQPVQLPAGGTS 778 Query: 779 FARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTR 838 FARW+ALL EHA++ V ADAWR VT+VP ALP V P DTY TA LS SLD +TTR Sbjct: 779 FARWAALLDEHARSQDVVATADAWREVTAVPAALPAVMPGLDTYATAKTLSVSLDADTTR 838 Query: 839 QLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELAS----DVDL 894 +LL EVPAAF AGVQDILL+AFGLAW EFL+ + T IG+ VEGHGR +EL D+DL Sbjct: 839 ELLSEVPAAFHAGVQDILLIAFGLAWNEFLDSNTTSIGIGVEGHGRQEELGRVAGLDIDL 898 Query: 895 SRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNP 954 SRTVGWFTTKYPV+L+V L W+++ G LG I+K+ KEQLR+LP+ LTYGLLRYLNP Sbjct: 899 SRTVGWFTTKYPVSLSVGGLSWKEIADGSPDLGPIIKSAKEQLRALPDPLTYGLLRYLNP 958 Query: 955 EVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAG 1014 +VDL G +P IGFNYLGRLGAGA +L+++LWRI++ V MPLM+TV+LNAG Sbjct: 959 DVDLSGPEPAIGFNYLGRLGAGAADLTDDLWRINEDSLSSAGVASSVSMPLMYTVDLNAG 1018 Query: 1015 TID----TDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDV 1070 ++ + GP LRA WTWAPS+ E Q RLS+LWFEALAGICA+VRGGGGGLTPSD+ Sbjct: 1019 IVEGGLGEEAGPHLRAGWTWAPSSVTEPQVQRLSQLWFEALAGICAYVRGGGGGLTPSDI 1078 Query: 1071 APARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGD--------DVYAVQLD 1122 APA+L+Q+QIDEL +++ + DVLPLTP+Q+GLLFH+TFAR G D YAVQLD Sbjct: 1079 APAQLSQQQIDELHEQHKIVDVLPLTPIQEGLLFHTTFARAAGALEGDEAGIDFYAVQLD 1138 Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 IT+TG++DQ RLRDAVHTVV RHPNLAARF QFG+PVQV+ ADP+IAWRYLDLRGDDLT Sbjct: 1139 ITVTGLVDQLRLRDAVHTVVRRHPNLAARFCTQFGDPVQVILADPVIAWRYLDLRGDDLT 1198 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 PD EI+ LCAAER+AVCDL +RPT RAALIRT GNQHRFVLTFHH+VIDGWSLPILLQEI Sbjct: 1199 PDEEIQHLCAAERAAVCDLADRPTLRAALIRTEGNQHRFVLTFHHVVIDGWSLPILLQEI 1258 Query: 1243 FAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIES 1302 FA YFGHRLPA + YR+FV+WL W +VL+GF+TPTLVAPP PG RG+ES Sbjct: 1259 FASYFGHRLPAPSSYRSFVSWLADQDLDAARTAWGKVLEGFDTPTLVAPPAPPGARGVES 1318 Query: 1303 YRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAE 1362 YRVSAETT+ALG+LARSQHTT++TVLQAAW QLLM +TGQ DVAFGTAVSGRPA+LAG++ Sbjct: 1319 YRVSAETTQALGDLARSQHTTVSTVLQAAWAQLLMVLTGQDDVAFGTAVSGRPAELAGSD 1378 Query: 1363 SMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTL 1422 S+VGLLINTVP+RA+ +A TT+ +LL QLQS HNDT+EHEHLALN+IHHV+GHEQLFDTL Sbjct: 1379 SIVGLLINTVPVRARATASTTIAELLGQLQSAHNDTIEHEHLALNEIHHVAGHEQLFDTL 1438 Query: 1423 FLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEI 1482 FLYESYPIDTSAFMGVQELA+TEF REYNHYPLSVMALPGHELG+RVEYDT F + +I Sbjct: 1439 FLYESYPIDTSAFMGVQELAITEFVTREYNHYPLSVMALPGHELGIRVEYDTDKFGLDDI 1498 Query: 1483 ETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFA 1542 + + +RF+R+L +M+ D +RLSS+DV+ DE QLD W NR VL + + SIPE FA Sbjct: 1499 QAVFERFERVLVSMVSDADQRLSSLDVLQTDEHKQLDGWGNRKVLVRGPEPVLSIPEAFA 1558 Query: 1543 RQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAI 1602 QV+R PEA A+TFEG S YGELDEAAN+LANLL+VYGAAPG+SVAL++PRS +AI+AI Sbjct: 1559 EQVDRAPEAVALTFEGRSTTYGELDEAANRLANLLSVYGAAPGESVALLMPRSDEAIIAI 1618 Query: 1603 LAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEV----DD 1658 LA+LKTGA+YLPIDPSVP RLEFML DA P+AAVTT +LR+RFDG + VV+ DD Sbjct: 1619 LAILKTGASYLPIDPSVPDTRLEFMLSDAVPIAAVTTAELRARFDGSGVSVVQFDDAEDD 1678 Query: 1659 PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAV 1718 P IY T LLTP+PDDIAY IYTSGTTGVPKGVAI H NVTQ L +P GPG V Sbjct: 1679 PTGAIYGHTPLLTPAPDDIAYTIYTSGTTGVPKGVAIAHSNVTQALKFPLTHMPTGPGEV 1738 Query: 1719 WSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVR 1778 W+Q SLVFD++VWEI+GALLHGGRLVI+P+S+ SPDD LL+ E V VL+QTPSAV Sbjct: 1739 WTQAGSLVFDITVWEIFGALLHGGRLVIIPDSVVRSPDDFRDLLIREKVTVLFQTPSAVG 1798 Query: 1779 MMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVP 1838 M+SPEGL LVVAGEACPTEVVDRWA RVMIN YGPTE+TIYA L GS VVP Sbjct: 1799 MLSPEGLNNLTLVVAGEACPTEVVDRWAPGRVMINGYGPTETTIYATF-GELIAGSGVVP 1857 Query: 1839 IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGA 1898 IG PVP A FVLD W+RPVPPGVVGELY+A LT RFVACPFGEPG Sbjct: 1858 IGVPVPDAALFVLDRWMRPVPPGVVGELYVAGLGVGIGYVKRQALTAARFVACPFGEPGT 1917 Query: 1899 RMYRTGDLVRWG----DDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIA 1954 RMYRTGDLVRWG GQL+YLGRADEQVKIRG+RIELGEIQAAL+DVDGV+QA VIA Sbjct: 1918 RMYRTGDLVRWGVSESSVGQLEYLGRADEQVKIRGFRIELGEIQAALADVDGVEQAAVIA 1977 Query: 1955 REDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALP 2014 REDRPGDKRLVGY GT +PA R+ L RLP YMVPAA+V LE LPLTVNGKLD+RALP Sbjct: 1978 REDRPGDKRLVGYFIGTGEPAELRAALAKRLPPYMVPAALVRLEALPLTVNGKLDKRALP 2037 Query: 2015 APEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTA 2074 APEY A RYRAP E+ +AGI+A VLGVER AMRV AA+NT+ Sbjct: 2038 APEYDDAARYRAPANAVEEAVAGIYAQVLGVERVGTDDSFFDLGGDSISAMRVVAAINTS 2097 Query: 2075 LDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAAVHGSDVTEVHARDLTLDKFIXX 2134 DA L+VRTLFEAP+V LS +++ AG + ++A+VHG TEV A DLTLDKFI Sbjct: 2098 FDAQLAVRTLFEAPSVRSLSGYLDGAAGAPANGPTYASVHGPGATEVRASDLTLDKFIDE 2157 Query: 2135 XXXXXXXXXXXXXGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDAR 2194 +TVLLTGATGFLGRYL+L+WLR+L +VD +ICLVR KSDE+AR Sbjct: 2158 ATLQKAPTLPRAEATARTVLLTGATGFLGRYLVLQWLRELEQVDGTLICLVRAKSDEEAR 2217 Query: 2195 RRLEATFDT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAA 2253 RRL+ TFD+ DP L + + LA +RLQV+AGDK +P+LGLD+ TWQRLA++VDLIVDSAA Sbjct: 2218 RRLDKTFDSGDPELIRVYEALAADRLQVIAGDKAEPSLGLDQDTWQRLADTVDLIVDSAA 2277 Query: 2254 FVNSVLPYSELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLV 2313 VNSVLPYSELFGPNVVGTAELIRFALT+KLKP+ ++ST+DVGR+IE S F E ADIR++ Sbjct: 2278 LVNSVLPYSELFGPNVVGTAELIRFALTTKLKPYTYISTADVGREIEKSVFREDADIRVI 2337 Query: 2314 SATRKIEVGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTV 2373 SATR + YANGYGNSKWAGEVLLREAH+ GLPV VFRSGMIMVD +YAGQ+N +DTV Sbjct: 2338 SATRPSDGSYANGYGNSKWAGEVLLREAHEQVGLPVKVFRSGMIMVDTSYAGQVNASDTV 2397 Query: 2374 SRMVLSIVATGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTAS 2433 +RMVLS+VATGVAP S YQ +G RQRAHFDGLPV+FVA+AIT LG A S S + Sbjct: 2398 ARMVLSVVATGVAPYSVYQLDADGNRQRAHFDGLPVEFVAEAITALGGGAAGSFDGS--A 2455 Query: 2434 GFETYHVMNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSV 2493 FETYHVMNPHDDGIGID Y+DWLIEAG+PIERI+DFGEW+++FEA L L D QRQ SV Sbjct: 2456 DFETYHVMNPHDDGIGIDEYVDWLIEAGHPIERIDDFGEWVRQFEARLHALPDHQRQGSV 2515 Query: 2494 LQMLTLLKQQAGELQPPVPTRGSFAPADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDL 2553 LQML +L+ + QPP P RG APADRF AAVR A IG + +IP V+ +I KY +DL Sbjct: 2516 LQMLKILQDHGWDGQPPEPVRGPMAPADRFHAAVRKAKIGSDHDIPQVSAPIIAKYASDL 2575 Query: 2554 QLLGLL 2559 QL GLL Sbjct: 2576 QLHGLL 2581 >tr|A5A9U3|A5A9U3_MYCAB Tax_Id=36809 (mps2)SubName: Full=Mps2 protein;[Mycobacterium abscessus] Length = 2581 Score = 3549 bits (9202), Expect = 0.0 Identities = 1795/2586 (69%), Positives = 2070/2586 (80%), Gaps = 32/2586 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M+A+P TRTLLS DLLD+D+HD+++ WGNRAVLT+P PV+IP +FA QV RAP+ VAL Sbjct: 1 MSADP-TRTLLSMDLLDDDDHDRLDEWGNRAVLTEPAAEPVSIPVVFAVQVERAPETVAL 59 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V DRSWTYRELD+ +NR+AH+LA +GA PG V L+PRSGEAI+ +L++LKTGAAYLP Sbjct: 60 VCRDRSWTYRELDQITNRIAHLLAGNGAGPGEVVGLLVPRSGEAIIGLLAILKTGAAYLP 119 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAHPD RI FM+SDA PVA LTTADL SR + D++VI++ DP ID +PS AL P P Sbjct: 120 IDPAHPDERIKFMVSDAGPVAVLTTADLGSRFEGLDVSVIEIDDPLIDGQPSSALPTPEP 179 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLV A+ ADLP+ PG+VWSQWHSLVFDVSVWEI Sbjct: 180 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVDAVRADLPARPGEVWSQWHSLVFDVSVWEI 239 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPESV SSPDDLH LLI+EKVSVLCQTPSAAGMLSPE LESTTLIVAG Sbjct: 240 WGALLHGGRLVVVPESVASSPDDLHELLISEKVSVLCQTPSAAGMLSPERLESTTLIVAG 299 Query: 301 EACPTELVDRWAP-GRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 EACP ELVDRWA GR MINAYGPTEATIYAAMS PL LFVLDK Sbjct: 300 EACPPELVDRWATSGRTMINAYGPTEATIYAAMSGPLTPGSGVAPIGSPVPGAALFVLDK 359 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WLRPAPEGVVGELYVAG+GVA GY R LTASRF+ACPFG G RMYRTGDLV+WG DG Sbjct: 360 WLRPAPEGVVGELYVAGNGVAPGYAHRSGLTASRFLACPFGGPGSRMYRTGDLVQWGEDG 419 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVKIRGYRIELGEIQAAL++LDGV+QAVVIAREDRPGDKRLVGYI GTAD Sbjct: 420 QLQYLGRADEQVKIRGYRIELGEIQAALSRLDGVEQAVVIAREDRPGDKRLVGYIMGTAD 479 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 P + R ALAE LPAYMVP AVVVLD +PLTVNGKLD+RALPAPEYRS DYRAPS P E Sbjct: 480 PVEARNALAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRSVGTDYRAPSGPVE 539 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 ++LAD+YAQVLGV+RVGVD+SFFDLGGDSILSMQVV+RARAAG+ CRPRDIFVEQT Sbjct: 540 KVLADIYAQVLGVDRVGVDESFFDLGGDSILSMQVVSRARAAGVHCRPRDIFVEQTVSGV 599 Query: 600 XXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVI 658 + +VD+G+GPV+ATPI+ WL+ V GP QFNQT++ QAP GVTEDDVVVI Sbjct: 600 AAVASLSDGRAGIVDDGIGPVLATPIIHWLQGVPGPVDQFNQTIVLQAPVGVTEDDVVVI 659 Query: 659 LQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLD 718 LQALLDRHATLRLR E + + + WSLLVP+ G V AR CLR ++L+D LV AR+RL+ Sbjct: 660 LQALLDRHATLRLRAE-SGDASGGWSLLVPDTGTVDARACLRVAESLSDAELVAARSRLN 718 Query: 719 PAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTS 778 PAAGA +SAVWV ++ QL LMIHHLAVDGVSWRILLEDLNIAWAQH GQ ++LPAGGTS Sbjct: 719 PAAGAQLSAVWVPDSRQLALMIHHLAVDGVSWRILLEDLNIAWAQHHGGQPVQLPAGGTS 778 Query: 779 FARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTR 838 FARW+ALL EHA++ V ADAWR VT+VP ALP V P DTY TA LS SLD +TTR Sbjct: 779 FARWAALLDEHARSQDVVATADAWREVTAVPAALPAVMPGLDTYATAKTLSVSLDADTTR 838 Query: 839 QLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELAS----DVDL 894 +LL EVPAAF AGVQDILL+AFGLAW EFL+ + T IG+ VEGHGR +EL D+DL Sbjct: 839 ELLSEVPAAFHAGVQDILLIAFGLAWNEFLDSNTTSIGIGVEGHGRQEELGRVAGLDIDL 898 Query: 895 SRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNP 954 SRTVGWFTTKYPV+L+V L W+++ G LG I+K+ KEQLR+LP+ LTYGLLRYLNP Sbjct: 899 SRTVGWFTTKYPVSLSVGGLSWKEIADGSPDLGPIIKSAKEQLRALPDPLTYGLLRYLNP 958 Query: 955 EVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAG 1014 +VDL G +P IGFNYLGRLGAGA +L+++LWRI++ V MPLM+TV+LNAG Sbjct: 959 DVDLSGPEPAIGFNYLGRLGAGAADLTDDLWRINEDSLSSAGVASSVSMPLMYTVDLNAG 1018 Query: 1015 TID----TDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDV 1070 ++ + GP LRA WTWAPS+ E Q RLS+LWFEALAGICA+VRGGGGGLTPSD+ Sbjct: 1019 IVEGGLGEEAGPHLRAGWTWAPSSVTEPQVQRLSQLWFEALAGICAYVRGGGGGLTPSDI 1078 Query: 1071 APARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGD--------DVYAVQLD 1122 APA+L+Q+QIDEL +++ + DVLPLTP+Q+GLLFH+TFAR G D YAVQLD Sbjct: 1079 APAQLSQQQIDELHEQHKIVDVLPLTPIQEGLLFHTTFARAAGALEGDEAGIDFYAVQLD 1138 Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 IT+TG++DQ RLRDAVHTVV RHPNLAARF QFG+PVQV+ ADP+IAWRYLDLRGDDLT Sbjct: 1139 ITVTGLVDQLRLRDAVHTVVRRHPNLAARFCTQFGDPVQVILADPVIAWRYLDLRGDDLT 1198 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 PD EI+ LCAAER+AVCDL +RPT RAALIRT GNQHRFVLTFHH+VIDGWSLPILLQEI Sbjct: 1199 PDEEIQHLCAAERAAVCDLADRPTLRAALIRTEGNQHRFVLTFHHVVIDGWSLPILLQEI 1258 Query: 1243 FAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIES 1302 FA YFGHRLPA + YR+FV+WL W +VL+GF+TPTLVAPP PG RG+ES Sbjct: 1259 FASYFGHRLPAPSSYRSFVSWLADQDLDAARTAWGKVLEGFDTPTLVAPPAPPGARGVES 1318 Query: 1303 YRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAE 1362 YRVSAETT+ALG+LARSQHTT++TVLQAAW QLLM +TGQ DVAFGTAVSGRPA+LAG++ Sbjct: 1319 YRVSAETTQALGDLARSQHTTVSTVLQAAWAQLLMVLTGQDDVAFGTAVSGRPAELAGSD 1378 Query: 1363 SMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTL 1422 S+VGLLINTVP+RA+ +A TT+ +LL QLQS HNDT+EHEHLALN+IHHV+GHEQLFDTL Sbjct: 1379 SIVGLLINTVPVRARATASTTIAELLGQLQSAHNDTIEHEHLALNEIHHVAGHEQLFDTL 1438 Query: 1423 FLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEI 1482 FLYESYPIDTSAFMGVQELA+TEF REYNHYPLSVMALPGHELG+RVEYDT F + +I Sbjct: 1439 FLYESYPIDTSAFMGVQELAITEFVTREYNHYPLSVMALPGHELGIRVEYDTDKFGLDDI 1498 Query: 1483 ETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFA 1542 + + +RF+R+L +M+ D +RLSS+DV+ DE QLD W NR VL + + SIPE FA Sbjct: 1499 QAVFERFERVLVSMVSDADQRLSSLDVLQTDEHKQLDGWGNRKVLVRGPEPVLSIPEAFA 1558 Query: 1543 RQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAI 1602 QV+R PEA A+TFEG S YGELDEAAN+LANLL+VYGAAPG+SVAL++PRS +AI+AI Sbjct: 1559 EQVDRAPEAVALTFEGRSTTYGELDEAANRLANLLSVYGAAPGESVALLMPRSDEAIIAI 1618 Query: 1603 LAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEV----DD 1658 LA+LKTGA+YLPIDPSVP RLEFML DA P+AAVTT +LR+RFDG + VV+ DD Sbjct: 1619 LAILKTGASYLPIDPSVPDTRLEFMLSDAVPIAAVTTAELRARFDGSGVSVVQFDDAEDD 1678 Query: 1659 PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAV 1718 P IY T LLTP+PDDIAY IYTSGTTGVPKGVAI H NVTQ L +P GPG V Sbjct: 1679 PTGAIYGHTPLLTPAPDDIAYTIYTSGTTGVPKGVAIAHSNVTQALKFPLTHMPTGPGEV 1738 Query: 1719 WSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVR 1778 W+Q SLVFD++VWEI+GALLHGGRLVI+P+S+ SPDD LL+ E V VL+QTPSAV Sbjct: 1739 WTQAGSLVFDITVWEIFGALLHGGRLVIIPDSVVRSPDDFRDLLIREKVTVLFQTPSAVG 1798 Query: 1779 MMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVP 1838 M+SPEGL LVVAGEACPTEVVDRWA RVMIN YGPTE+TIYA L GS VVP Sbjct: 1799 MLSPEGLNNLTLVVAGEACPTEVVDRWAPGRVMINGYGPTETTIYATF-GELIAGSGVVP 1857 Query: 1839 IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGA 1898 IG PVP A FVLD W+RPVPPGVVGELY+A LT RFVACPFGEPG Sbjct: 1858 IGVPVPDAALFVLDRWMRPVPPGVVGELYVAGLGVGIGYVKRQALTAARFVACPFGEPGT 1917 Query: 1899 RMYRTGDLVRWG----DDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIA 1954 RMYRTGDLVRWG GQL+YLGRADEQVKIRG+RIELGEIQAAL+DVDGV+QA VIA Sbjct: 1918 RMYRTGDLVRWGVSESSVGQLEYLGRADEQVKIRGFRIELGEIQAALADVDGVEQAAVIA 1977 Query: 1955 REDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALP 2014 REDRPGDKRLVGY GT +PA R+ L RLP YMVPAA+V LE LPLTVNGKLD+RALP Sbjct: 1978 REDRPGDKRLVGYFIGTGEPAELRAALAKRLPPYMVPAALVRLEALPLTVNGKLDKRALP 2037 Query: 2015 APEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTA 2074 APEY A RYRAP E+ +AGI+A VLGVER AMRV AA+NT+ Sbjct: 2038 APEYDDAARYRAPANAVEEAVAGIYAQVLGVERVGTDDSFFDLGGDSISAMRVVAAINTS 2097 Query: 2075 LDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAAVHGSDVTEVHARDLTLDKFIXX 2134 DA L+VRTLFEAP+V LS +++ AG + ++A+VHG TEV A DLTLDKFI Sbjct: 2098 FDAQLAVRTLFEAPSVRSLSGYLDGAAGAPANGPTYASVHGPGATEVRASDLTLDKFIDE 2157 Query: 2135 XXXXXXXXXXXXXGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDAR 2194 +TVLLTGATGFLGRYL+L+WLR+L +VD +ICLVR KSDE+AR Sbjct: 2158 ATLQKAPTLPRAEATARTVLLTGATGFLGRYLVLQWLRELEQVDGTLICLVRAKSDEEAR 2217 Query: 2195 RRLEATFDT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAA 2253 RRL+ TFD+ DP L + + LA +RLQV+AGDK +P+LGLD+ TWQRLA++VDLIVDSAA Sbjct: 2218 RRLDKTFDSGDPELIRVYEALAADRLQVIAGDKAEPSLGLDQDTWQRLADTVDLIVDSAA 2277 Query: 2254 FVNSVLPYSELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLV 2313 VNSVLPYSELFGPNVVGTAELIRFALT+KLKP+ ++ST+DVGR+IE S F E ADIR++ Sbjct: 2278 LVNSVLPYSELFGPNVVGTAELIRFALTTKLKPYTYISTADVGREIEKSVFREDADIRVI 2337 Query: 2314 SATRKIEVGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTV 2373 SATR + YANGYGNSKWAGEVLLREAH+ GLPV VFRSGMIMVD +YAGQ+N +DTV Sbjct: 2338 SATRPSDGSYANGYGNSKWAGEVLLREAHEQVGLPVKVFRSGMIMVDTSYAGQVNASDTV 2397 Query: 2374 SRMVLSIVATGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTAS 2433 +RMVLS+VATGVAP S YQ +G RQRAHFDGLPV+FVA+AIT LG A S S + Sbjct: 2398 ARMVLSVVATGVAPYSVYQLDADGNRQRAHFDGLPVEFVAEAITALGGGAAGSFDGS--A 2455 Query: 2434 GFETYHVMNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSV 2493 FETYHVMNPHDDGIGID Y+DWLIEAG+PIERI+DFGEW+++FEA L L D QRQ SV Sbjct: 2456 DFETYHVMNPHDDGIGIDEYVDWLIEAGHPIERIDDFGEWVRQFEARLHALPDHQRQGSV 2515 Query: 2494 LQMLTLLKQQAGELQPPVPTRGSFAPADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDL 2553 LQML +L+ + QPP P RG APADRF AAVR A IG + +IP V+ +I KY +DL Sbjct: 2516 LQMLKILQDHGWDGQPPEPVRGPMAPADRFHAAVRKAKIGSDHDIPQVSAPIIAKYASDL 2575 Query: 2554 QLLGLL 2559 QL GLL Sbjct: 2576 QLHGLL 2581 >tr|Q9XCF2|Q9XCF2_MYCAV Tax_Id=1764 (pstB)SubName: Full=PstB;[Mycobacterium avium] Length = 2552 Score = 3501 bits (9079), Expect = 0.0 Identities = 1773/2561 (69%), Positives = 2039/2561 (79%), Gaps = 24/2561 (0%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R LLS DLLD EHD+++ WGNRA+LT P P +IP +FA QV R+ +AVAL RS Sbjct: 7 RRLLSIDLLDGGEHDRLDEWGNRAILTKPVKAPASIPGMFAAQVARSAEAVALSFEGRSM 66 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 TYRELDEASNRLAH+LAE GA PG VA L RS EAI+SIL+VLKTGAAYLP+DPA P Sbjct: 67 TYRELDEASNRLAHLLAEQGAAPGECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPA 126 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAID---RRPSDALSGPRPDDLA 184 AR+ FM+ DA P+AA+TTA LR RL+ +DL VID+ + A + +PS AL GP PDD+A Sbjct: 127 ARMEFMLGDATPIAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIA 186 Query: 185 YMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGAL 244 YM YTSGTTG PK VAVTH NVT+ + LH LPSGPGQVWSQWHSLVFDVSVWE WGAL Sbjct: 187 YMIYTSGTTGTPKGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFDVSVWETWGAL 246 Query: 245 LHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAGEACP 304 LHGGRLVVVPESV SPDDLH+LL+ E V+VL QTPSA GMLSPEGL+ST L+VAGEACP Sbjct: 247 LHGGRLVVVPESVAGSPDDLHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAGEACP 306 Query: 305 TELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPA 364 E+VDRWAPGRVMINAYGPTEAT+YAAMS PL LFVLDKWLRPA Sbjct: 307 AEVVDRWAPGRVMINAYGPTEATVYAAMSAPLTAESGAPPIGSPVPGAALFVLDKWLRPA 366 Query: 365 PEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYL 424 PEGVVGELY+AG GVATGY R LTASRFVACPFG G RMYRTGDLVRWG+DGQL+YL Sbjct: 367 PEGVVGELYIAGRGVATGYARRAGLTASRFVACPFGGPGARMYRTGDLVRWGADGQLQYL 426 Query: 425 GRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPAQLR 484 GRADEQVKIRGYRIELGEIQ+ALA LDGVDQA VIAREDRPGDKRLVGYITGTADPA+LR Sbjct: 427 GRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYITGTADPAELR 486 Query: 485 TALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILAD 544 T L + LPAYMVP AVVVL+++PLTVNGKLD+RALPAPEY A YRAPS E+ILAD Sbjct: 487 TQLGKRLPAYMVPAAVVVLESLPLTVNGKLDKRALPAPEYHKRAGQYRAPSNHTEEILAD 546 Query: 545 VYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXX 604 +YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+FVEQT Sbjct: 547 IYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVICRPRDVFVEQTVARLARVAS 606 Query: 605 XXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALL 663 E VVDEG+GPV ATPIMRWL+ V GP FNQT++ AP+GVT DDV V+LQALL Sbjct: 607 DGADEEQVVDEGIGPVQATPIMRWLQTVQGPIDDFNQTMVLAAPSGVTADDVAVVLQALL 666 Query: 664 DRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGA 723 DRH LRLRVED + W+L PE G+V A +CL++VD L+D VLV AR+RL+P AG Sbjct: 667 DRHPMLRLRVED--DGAGGWNLQAPEPGSVRAADCLQSVDTLSDAVLVAARSRLNPGAGV 724 Query: 724 MVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWS 783 MVSAVW ETSQL L+IHH+AVDGVSWR L+EDLNIAWAQH +GQ + LPAGGTSFARWS Sbjct: 725 MVSAVWASETSQLALIIHHVAVDGVSWRTLIEDLNIAWAQHHSGQPVALPAGGTSFARWS 784 Query: 784 ALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGE 843 +LLAEHA T V + ADAWR V + P LP VQP+ DTY +A QLS SLDV+TTR LLGE Sbjct: 785 SLLAEHALTPAVVEQADAWREVVATPAVLPAVQPEVDTYQSAEQLSVSLDVDTTRLLLGE 844 Query: 844 VPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTT 903 VPAAF AGVQDILL+AF +AWT+ + + TPIG+DVEGHGR++EL VDLSRTVGWFTT Sbjct: 845 VPAAFHAGVQDILLIAFAMAWTQVVG-AGTPIGIDVEGHGRHEELGPHVDLSRTVGWFTT 903 Query: 904 KYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGGSDP 963 KYPVAL ++ L W VVAGD ALG VKA KEQLR+LP+GLTYGLLRYLNP+VDLGGSDP Sbjct: 904 KYPVALAIDGLDWASVVAGDDALGAAVKAAKEQLRALPDGLTYGLLRYLNPDVDLGGSDP 963 Query: 964 TIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPS 1023 IGFNYLGRLGA A +L ELWR+ V MPLMHTV++NAGT+DT++GP Sbjct: 964 VIGFNYLGRLGAAA-DLPGELWRLSPDSLSLSGAAAAVAMPLMHTVDVNAGTMDTEDGPH 1022 Query: 1024 LRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDEL 1083 L A+WTWAPSA D +Q +RLS+LWFEALAGICAHVR GGGGLTPSD+ PARL QRQIDEL Sbjct: 1023 LHANWTWAPSAVDRDQISRLSQLWFEALAGICAHVRAGGGGLTPSDILPARLNQRQIDEL 1082 Query: 1084 SQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVA 1143 S+++ + D+LPLTP+QQGLLFH++FA+ GDDVYAVQL IT+TG LD HRL DAVHTVV Sbjct: 1083 SKQHQIADILPLTPLQQGLLFHASFAQDPGDDVYAVQLGITVTGALDSHRLHDAVHTVVN 1142 Query: 1144 RHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLE 1203 RHPNLAARF Q+GEPVQV+ ADP++AWRY+ L +D+ P+ ++E+LCAAER+AV DL Sbjct: 1143 RHPNLAARFCPQYGEPVQVVPADPVMAWRYIQLGPEDVDPEQKVEELCAAERAAVSDLAN 1202 Query: 1204 RPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNW 1263 RP FRAALIRT+ N+HRFVLT HHIV+DGWSLPILL+EI A Y+G +LPA A YR+++ W Sbjct: 1203 RPAFRAALIRTADNRHRFVLTNHHIVMDGWSLPILLREILAIYYGDQLPAPATYRSYLTW 1262 Query: 1264 LXXXXXXXXXXXWREVLDGFETPTLVAPPGVP--GPRGIESYRVSAETTRALGELARSQH 1321 L WR+VLDGF+TPTLV P G G R +ESYR+SAETTRALGELAR+ H Sbjct: 1263 LAGQDRSAAQAAWRQVLDGFDTPTLVGPAGRMRLGRRAVESYRLSAETTRALGELARACH 1322 Query: 1322 TTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSAD 1381 TT+NTVLQA W QLLMR+TGQ DVAFGTAVSGRPADLAGAESMVGLLINTVP+RA A+ Sbjct: 1323 TTVNTVLQAGWAQLLMRLTGQHDVAFGTAVSGRPADLAGAESMVGLLINTVPVRANTHAE 1382 Query: 1382 TTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQEL 1441 TTV DLL QLQ HHNDTLEHEHLAL++IH V+GH+ LFDTLFLYE+YPIDTS +G EL Sbjct: 1383 TTVADLLDQLQQHHNDTLEHEHLALSEIHRVTGHDALFDTLFLYENYPIDTSVPLGFHEL 1442 Query: 1442 AVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPA 1501 A+T+ NREYNHYPLSVMALPG ELGLRVE+DT VFD + IE L +RFQR+L M DP Sbjct: 1443 AITDVTNREYNHYPLSVMALPGRELGLRVEFDTDVFDAAGIEKLTERFQRVLSEMTADPT 1502 Query: 1502 RRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESL 1561 RRL+S++V+D+ E LD W NR VL+QP SIP +FA QV R P+A A+TF+G S+ Sbjct: 1503 RRLTSLEVMDEAEHELLDAWGNRPVLSQPATGT-SIPALFAAQVARTPDAAALTFQGRSM 1561 Query: 1562 NYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPA 1621 +Y ELDEA+N+LA+LL GA PG+ VAL+ RSA+AIV+ILAVLKTGAAYLPIDP++PA Sbjct: 1562 SYRELDEASNRLAHLLIEEGAGPGECVALLFSRSAEAIVSILAVLKTGAAYLPIDPALPA 1621 Query: 1622 ARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMI 1681 AR+EF+LGDA+PVA VTT LRSR DG VV+VDDPA++ PS L PS D+IAY+I Sbjct: 1622 ARIEFLLGDAEPVAVVTTAALRSRLDGCKPSVVDVDDPALDGQPSAALPVPSSDNIAYLI 1681 Query: 1682 YTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHG 1741 YTSGTTGVPKGVA++H NV Q++++L A+LP G VW+QWHSLVFDVSV EIWGALLHG Sbjct: 1682 YTSGTTGVPKGVAVSHDNVAQLVESLHADLPEG--GVWAQWHSLVFDVSVHEIWGALLHG 1739 Query: 1742 GRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEV 1801 GRLV+VPES+A SPD+LH LLV+EGV VL QTPSAV M+SPEGL+ TALVVAGEACP E+ Sbjct: 1740 GRLVVVPESVAASPDELHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAGEACPVEI 1799 Query: 1802 VDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPG 1861 VDRWA RVMINAYGPTE+T+YAA+S PL PG+ PIGSPVP+ A FVLD WLRP PPG Sbjct: 1800 VDRWAPGRVMINAYGPTEATVYAAMSTPLQPGTGSAPIGSPVPRAALFVLDRWLRPAPPG 1859 Query: 1862 VVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRA 1921 VVGELY+A LT +RFVACPFG PGARMYRTGDLVRW DGQL+YLGRA Sbjct: 1860 VVGELYIAGHGVATGYARRSGLTASRFVACPFGGPGARMYRTGDLVRWNQDGQLEYLGRA 1919 Query: 1922 DEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSEL 1981 DEQVK+RGYRIELGE+QAAL+ +DGV+QA VIAREDRPGDKRLVGYITGTADP R +L Sbjct: 1920 DEQVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPGDKRLVGYITGTADPVGIRIQL 1979 Query: 1982 TNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFA 2040 RLPAYMVPAAVV L+ LPLTVNGKLD+RALPAPEY+ Y AP TE+T+AGIFA Sbjct: 1980 AERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRKRGGEYIAPTNPTEETVAGIFA 2039 Query: 2041 HVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD 2100 VLG+ER AMRV A +NTA+D LSVRTLF++ +V LS + Sbjct: 2040 RVLGMERVSIDDSFFELGGDSLSAMRVIAEINTAVDGALSVRTLFDSQSVRALSQRITSG 2099 Query: 2101 A-GERTDRVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXXXXXXXXGAVQTVLLTGAT 2159 A E FAAVHG+D EV+ARDLTLDKF+ V+TVLLTGAT Sbjct: 2100 ADAENAAGPGFAAVHGADAKEVYARDLTLDKFLDATTLSTAPTLPGPSPEVRTVLLTGAT 2159 Query: 2160 GFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDT-DPLLRKHFNELATER 2218 GFLGRYL+LEWL QL +VD K+ICLVR +SDE+A RLE TF+T DP L +HF ELA E Sbjct: 2160 GFLGRYLVLEWLEQLEQVDGKLICLVRARSDEEAWGRLEKTFNTGDPELLRHFQELAEEH 2219 Query: 2219 LQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRF 2278 LQVVAGDKGQ NLGLDEQTWQ+LA++VDLIVDSAA VN VLPYSELF PNV GTAELIR Sbjct: 2220 LQVVAGDKGQANLGLDEQTWQQLADTVDLIVDSAAVVNGVLPYSELFTPNVGGTAELIRL 2279 Query: 2279 ALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLL 2338 ALT++ KPF +VSTSDVGRQIEPS FTE ADIR++SATR I+ YANGYGNSKWAGEVLL Sbjct: 2280 ALTTRKKPFAYVSTSDVGRQIEPSAFTEDADIRVISATRVIDGSYANGYGNSKWAGEVLL 2339 Query: 2339 REAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGE 2398 REAHD CGLPV+VFRS MI+ D +YAGQLNVTD +RM+LSIVATG AP SFY+ +G Sbjct: 2340 REAHDLCGLPVSVFRSDMILADTSYAGQLNVTDIFTRMILSIVATGTAPKSFYRLDADGN 2399 Query: 2399 RQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLI 2458 RQR+HFD LPV+FVA+AI KLG QV GFETYHVMNPHDDGIG+D Y+DWLI Sbjct: 2400 RQRSHFDALPVEFVAEAIAKLGAQV--------MDGFETYHVMNPHDDGIGLDEYVDWLI 2451 Query: 2459 EAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFA 2518 EAGYPIER++DFGEWLQRFE L+GL ++QRQNSVLQML LL + LQP P RG+FA Sbjct: 2452 EAGYPIERVDDFGEWLQRFETGLRGLPERQRQNSVLQMLLLLLRDPKNLQPAEPARGAFA 2511 Query: 2519 PADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 P DRF+AAV++A +G + +IPH++ VIVKYVTDLQLLGLL Sbjct: 2512 PTDRFRAAVQEAKVGSDNDIPHISAPVIVKYVTDLQLLGLL 2552 Score = 798 bits (2060), Expect = 0.0 Identities = 404/581 (69%), Positives = 464/581 (79%), Gaps = 4/581 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P TR L S +++DE EH+ ++ WGNR VL+ P T +IPALFA QV R PDA AL Sbjct: 1497 MTADP-TRRLTSLEVMDEAEHELLDAWGNRPVLSQPA-TGTSIPALFAAQVARTPDAAAL 1554 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS +YRELDEASNRLAH+L E GA PG VA L RS EAI+SIL+VLKTGAAYLP Sbjct: 1555 TFQGRSMSYRELDEASNRLAHLLIEEGAGPGECVALLFSRSAEAIVSILAVLKTGAAYLP 1614 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P ARI F++ DA+PVA +TTA LRSRLD +V+D+ DPA+D +PS AL P Sbjct: 1615 IDPALPAARIEFLLGDAEPVAVVTTAALRSRLDGCKPSVVDVDDPALDGQPSAALPVPSS 1674 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D++AY+ YTSGTTGVPK VAV+H NV QLV +LHADLP G VW+QWHSLVFDVSV EI Sbjct: 1675 DNIAYLIYTSGTTGVPKGVAVSHDNVAQLVESLHADLPE--GGVWAQWHSLVFDVSVHEI 1732 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPESV +SPD+LH+LL+ E V+VL QTPSA GMLSPEGL+ST L+VAG Sbjct: 1733 WGALLHGGRLVVVPESVAASPDELHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAG 1792 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP E+VDRWAPGRVMINAYGPTEAT+YAAMS PL LFVLD+W Sbjct: 1793 EACPVEIVDRWAPGRVMINAYGPTEATVYAAMSTPLQPGTGSAPIGSPVPRAALFVLDRW 1852 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRPAP GVVGELY+AGHGVATGY R LTASRFVACPFG G RMYRTGDLVRW DGQ Sbjct: 1853 LRPAPPGVVGELYIAGHGVATGYARRSGLTASRFVACPFGGPGARMYRTGDLVRWNQDGQ 1912 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 LEYLGRADEQVK+RGYRIELGE+QAALA LDGV+QA VIAREDRPGDKRLVGYITGTADP Sbjct: 1913 LEYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPGDKRLVGYITGTADP 1972 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 +R LAE LPAYMVP AVVVLD +PLTVNGKLD+RALPAPEYR +Y AP+ P E+ Sbjct: 1973 VGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRKRGGEYIAPTNPTEE 2032 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA 581 +A ++A+VLG+ERV +DDSFF+LGGDS+ +M+V+A A Sbjct: 2033 TVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVIAEINTA 2073 >tr|A0QHN7|A0QHN7_MYCA1 Tax_Id=243243 SubName: Full=Linear gramicidin synthetase subunit B; EC=5.1.1.-;[Mycobacterium avium] Length = 2552 Score = 3497 bits (9069), Expect = 0.0 Identities = 1772/2561 (69%), Positives = 2038/2561 (79%), Gaps = 24/2561 (0%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R LLS DLLD EHD+++ WGNRA+LT P P +IP +FA QV R+ +AVAL RS Sbjct: 7 RRLLSIDLLDGGEHDRLDEWGNRAILTKPVKAPASIPGMFAAQVARSAEAVALSFEGRSM 66 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 TYRELDEASNRLAH+LAE GA PG VA L RS EAI+SIL+VLKTGAAYLP+DPA P Sbjct: 67 TYRELDEASNRLAHLLAEQGAAPGECVALLFSRSDEAIVSILAVLKTGAAYLPIDPALPA 126 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAID---RRPSDALSGPRPDDLA 184 AR+ FM+ DA P+AA+TTA LR RL+ +DL VID+ + A + +PS AL GP PDD+A Sbjct: 127 ARMEFMLGDATPIAAVTTAGLRDRLEGFDLPVIDVDEAAAEIERTQPSSALPGPSPDDIA 186 Query: 185 YMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGAL 244 YM YTSGTTG PK VAVTH NVT+ + LH LPSGPGQVWSQWHSLVFDVSVWE WGAL Sbjct: 187 YMIYTSGTTGTPKGVAVTHRNVTEFLKTLHPKLPSGPGQVWSQWHSLVFDVSVWETWGAL 246 Query: 245 LHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAGEACP 304 LHGGRLVVVPESV SPDDLH+LL+ E V+VL QTPSA GMLSPEGL+ST L+VAGEACP Sbjct: 247 LHGGRLVVVPESVAGSPDDLHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAGEACP 306 Query: 305 TELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPA 364 E+VDRWAPGRVMINAYGPTEAT+YAAMS PL LFVLDKWLRPA Sbjct: 307 AEVVDRWAPGRVMINAYGPTEATVYAAMSAPLTAESGAPPIGSPVPGAALFVLDKWLRPA 366 Query: 365 PEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYL 424 PEGVVGELY+AG GVATGY R LTASRFVACPFG G RMYRTGDLVRWG+DGQL+YL Sbjct: 367 PEGVVGELYIAGRGVATGYARRAGLTASRFVACPFGGPGARMYRTGDLVRWGADGQLQYL 426 Query: 425 GRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPAQLR 484 GRADEQVKIRGYRIELGEIQ+ALA LDGVDQA VIAREDRPGDKRLVGYITGTADPA+LR Sbjct: 427 GRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYITGTADPAELR 486 Query: 485 TALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILAD 544 T L + LPAYMVP AVVVL+++PLTVNGKLD+RALPAPEY A YRAPS E+ILAD Sbjct: 487 TQLGKRLPAYMVPAAVVVLESLPLTVNGKLDKRALPAPEYHKRAGQYRAPSNHTEEILAD 546 Query: 545 VYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXX 604 +YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+FVEQT Sbjct: 547 IYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVICRPRDVFVEQTVARLARVAS 606 Query: 605 XXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALL 663 E VVDEG+GPV ATPIMRWL+ V GP FNQT++ AP+GVT DDV V+LQALL Sbjct: 607 DGADEEQVVDEGIGPVQATPIMRWLQTVQGPIDDFNQTMVLAAPSGVTADDVAVVLQALL 666 Query: 664 DRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGA 723 DRH LRLRVED + W+L PE G+V A +CL++VD L+D VLV AR+RL+P AG Sbjct: 667 DRHPMLRLRVED--DGAGGWNLQAPEPGSVRAADCLQSVDTLSDAVLVAARSRLNPGAGV 724 Query: 724 MVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWS 783 MVSAVW ETSQL L+IHH+AVDGVSWR L+EDLNIAWAQH +GQ + LPAGGTSFARWS Sbjct: 725 MVSAVWASETSQLALIIHHVAVDGVSWRTLIEDLNIAWAQHHSGQPVALPAGGTSFARWS 784 Query: 784 ALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGE 843 +LLAEHA T V + ADAWR V + P LP VQP+ DTY +A QLS SLDV+TTR LLGE Sbjct: 785 SLLAEHALTPAVVEQADAWREVVATPAVLPAVQPEVDTYQSAEQLSVSLDVDTTRLLLGE 844 Query: 844 VPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTT 903 VPAAF AGVQDILL+AF +AWT+ + + TPIG+DVEGHGR++EL VDLSRTVGWFTT Sbjct: 845 VPAAFHAGVQDILLIAFAMAWTQVVG-AGTPIGIDVEGHGRHEELGPHVDLSRTVGWFTT 903 Query: 904 KYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGGSDP 963 KYPVAL ++ L W VVAGD ALG VKA KEQLR+LP+GLTYGLLRYLNP+VDLGGSDP Sbjct: 904 KYPVALAIDGLDWASVVAGDDALGAAVKAAKEQLRALPDGLTYGLLRYLNPDVDLGGSDP 963 Query: 964 TIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPS 1023 IGFNYLGRLGA A +L ELWR+ V MPLMHTV+LNAGT+DT++GP Sbjct: 964 VIGFNYLGRLGAAA-DLPGELWRLSPDSLSLSGAAAAVAMPLMHTVDLNAGTMDTEDGPH 1022 Query: 1024 LRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDEL 1083 L A+WTWAPSA D +Q +RLS+LWFEALAGICAHVR GGGGLTPSD+ PARL QRQIDEL Sbjct: 1023 LHANWTWAPSAVDRDQISRLSQLWFEALAGICAHVRAGGGGLTPSDILPARLNQRQIDEL 1082 Query: 1084 SQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVA 1143 S+++ + D+LPLTP+QQGLLFH++FA+ GDDVYAVQL IT+TG LD HRL DAVHTVV Sbjct: 1083 SKQHQIADILPLTPLQQGLLFHASFAQDPGDDVYAVQLGITVTGALDSHRLHDAVHTVVN 1142 Query: 1144 RHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLE 1203 RHPNLAARF Q+GEPVQV+ ADP++AWRY+ L +D+ P+ ++E+LCAAER+AV DL Sbjct: 1143 RHPNLAARFCPQYGEPVQVVPADPVMAWRYIQLGPEDVDPEQKVEELCAAERAAVSDLAN 1202 Query: 1204 RPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNW 1263 RP FRAALIRT+ N+HRFVLT HHIV+DGWSLPILL+EI A Y+G +LPA A YR+++ W Sbjct: 1203 RPAFRAALIRTADNRHRFVLTNHHIVMDGWSLPILLREILAIYYGDQLPAPATYRSYLTW 1262 Query: 1264 LXXXXXXXXXXXWREVLDGFETPTLVAPPGVP--GPRGIESYRVSAETTRALGELARSQH 1321 L WR+VLDGF+TPTLV P G G R +ESYR+SA+TTRALGELAR+ H Sbjct: 1263 LAGQDRSAAQAAWRQVLDGFDTPTLVGPAGRMRLGRRAVESYRLSADTTRALGELARACH 1322 Query: 1322 TTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSAD 1381 TT+NTVLQA W QLLMR+TGQ DVAFGTAVSGRPADLAGAESMVGLLINTVP+RA A+ Sbjct: 1323 TTVNTVLQAGWAQLLMRLTGQHDVAFGTAVSGRPADLAGAESMVGLLINTVPVRANTHAE 1382 Query: 1382 TTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQEL 1441 TTV DLL QLQ HHNDTLEHEHLAL++IH V+GH+ LFDTLFLYE+YPIDTS +G EL Sbjct: 1383 TTVADLLDQLQQHHNDTLEHEHLALSEIHRVTGHDALFDTLFLYENYPIDTSVPLGFHEL 1442 Query: 1442 AVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPA 1501 A+T+ NREYNHYPLSVMALPG ELGLRVE+DT VFD + IE L +RFQR+L M DP Sbjct: 1443 AITDVTNREYNHYPLSVMALPGRELGLRVEFDTDVFDAAGIEKLTERFQRVLSEMTADPT 1502 Query: 1502 RRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESL 1561 RRL+S++V+D+ E LD W NR VL+QP SIP +FA QV R P+A A+TF+G S+ Sbjct: 1503 RRLTSLEVMDEAEHELLDAWGNRPVLSQPATGT-SIPALFAAQVARTPDAAALTFQGRSM 1561 Query: 1562 NYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPA 1621 +Y ELDEA+N+LA+LL GA PG+ VAL+ RSA+AIV+ILAVLKTGAAYLPIDP++PA Sbjct: 1562 SYRELDEASNRLAHLLIEEGAGPGECVALLFSRSAEAIVSILAVLKTGAAYLPIDPALPA 1621 Query: 1622 ARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMI 1681 AR+EF+LGDA+PVA VTT LRSR DG VV+VDDPA++ PS L PS D+IAY+I Sbjct: 1622 ARIEFLLGDAEPVAVVTTAALRSRLDGCKPSVVDVDDPALDGQPSAALPVPSSDNIAYLI 1681 Query: 1682 YTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHG 1741 YTSGTTGVPKGVA++H NV Q++++L A+LP G VW+QWHSLVFDVSV EIWGALLHG Sbjct: 1682 YTSGTTGVPKGVAVSHDNVAQLVESLHADLPEG--GVWAQWHSLVFDVSVHEIWGALLHG 1739 Query: 1742 GRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEV 1801 GRLV+VPES+A SPD+LH LLV+EGV VL QTPSAV M+SPEGL+ TALVVAGEACP E+ Sbjct: 1740 GRLVVVPESVAASPDELHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAGEACPVEI 1799 Query: 1802 VDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPG 1861 VDRWA RVMINAYGPTE+T+YAA+S PL PG+ PIGSPVP+ A FVLD WLRP PPG Sbjct: 1800 VDRWAPGRVMINAYGPTEATVYAAMSTPLQPGTGSAPIGSPVPRAALFVLDRWLRPAPPG 1859 Query: 1862 VVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRA 1921 VVGELY+A LT +RFVACPFG PGARMYRTGDLVRW DGQL+YLGRA Sbjct: 1860 VVGELYIAGHGVATGYARRSGLTASRFVACPFGGPGARMYRTGDLVRWNQDGQLEYLGRA 1919 Query: 1922 DEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSEL 1981 DEQVK+RGYRIELGE+QAAL+ +DGV+QA VIAREDRPGDKRLVGYITGTADP R +L Sbjct: 1920 DEQVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPGDKRLVGYITGTADPVGIRIQL 1979 Query: 1982 TNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFA 2040 RLPAYMVPAAVV L+ LPLTVNGKLD+RALPAPEY+ Y AP TE+T+AGIFA Sbjct: 1980 AERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRKRGGEYIAPTNPTEETVAGIFA 2039 Query: 2041 HVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD 2100 VLG+ER AMRV A +NTA+D LSVRTLF++ +V LS + Sbjct: 2040 RVLGMERVSIDDSFFELGGDSLSAMRVIAEINTAVDGALSVRTLFDSQSVRALSQRITSG 2099 Query: 2101 A-GERTDRVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXXXXXXXXGAVQTVLLTGAT 2159 A E FAAVHG+D EV+ARDLTLDKF+ V+TVLLTGAT Sbjct: 2100 ADAENAAGPGFAAVHGADAKEVYARDLTLDKFLDATTLSTAPTLPGPSPEVRTVLLTGAT 2159 Query: 2160 GFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDT-DPLLRKHFNELATER 2218 GFLGRYL+LEWL QL +VD K+ICLVR +SDE+A RLE TF+T DP L +HF ELA E Sbjct: 2160 GFLGRYLVLEWLEQLEQVDGKLICLVRARSDEEAWGRLEKTFNTGDPELLRHFQELAEEH 2219 Query: 2219 LQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRF 2278 LQVVAGDKGQ NLGLDEQTWQ+LA++VDLIVDSAA VN VLPYSELF PNV GTAELIR Sbjct: 2220 LQVVAGDKGQANLGLDEQTWQQLADTVDLIVDSAAVVNGVLPYSELFTPNVGGTAELIRL 2279 Query: 2279 ALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLL 2338 ALT++ KPF +VSTSDVGRQIEPS FTE ADIR++SATR I+ YANGYGNSKWAGEVLL Sbjct: 2280 ALTTRKKPFAYVSTSDVGRQIEPSAFTEDADIRVISATRVIDGSYANGYGNSKWAGEVLL 2339 Query: 2339 REAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGE 2398 REAHD CGLPV+VFRS MI+ D +YAGQLNVTD +RM+LSIVATG AP SFY+ +G Sbjct: 2340 REAHDLCGLPVSVFRSDMILADTSYAGQLNVTDIFTRMILSIVATGTAPKSFYRLDADGN 2399 Query: 2399 RQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLI 2458 RQR+HFD LPV+FVA+AI KLG QV GFETYHVMNPHDDGIG+D Y+DWLI Sbjct: 2400 RQRSHFDALPVEFVAEAIAKLGAQV--------MDGFETYHVMNPHDDGIGLDEYVDWLI 2451 Query: 2459 EAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFA 2518 EAGYPIER++DFGEWLQRFE L+GL ++QRQNSVLQML LL + LQ P RG+FA Sbjct: 2452 EAGYPIERVDDFGEWLQRFETGLRGLPERQRQNSVLQMLLLLLRDPKNLQLAEPARGAFA 2511 Query: 2519 PADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 P DRF+AAV++A +G + +IPH++ VIVKYVTDLQLLGLL Sbjct: 2512 PTDRFRAAVQEAKVGSDNDIPHISAPVIVKYVTDLQLLGLL 2552 Score = 798 bits (2060), Expect = 0.0 Identities = 404/581 (69%), Positives = 464/581 (79%), Gaps = 4/581 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P TR L S +++DE EH+ ++ WGNR VL+ P T +IPALFA QV R PDA AL Sbjct: 1497 MTADP-TRRLTSLEVMDEAEHELLDAWGNRPVLSQPA-TGTSIPALFAAQVARTPDAAAL 1554 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS +YRELDEASNRLAH+L E GA PG VA L RS EAI+SIL+VLKTGAAYLP Sbjct: 1555 TFQGRSMSYRELDEASNRLAHLLIEEGAGPGECVALLFSRSAEAIVSILAVLKTGAAYLP 1614 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P ARI F++ DA+PVA +TTA LRSRLD +V+D+ DPA+D +PS AL P Sbjct: 1615 IDPALPAARIEFLLGDAEPVAVVTTAALRSRLDGCKPSVVDVDDPALDGQPSAALPVPSS 1674 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D++AY+ YTSGTTGVPK VAV+H NV QLV +LHADLP G VW+QWHSLVFDVSV EI Sbjct: 1675 DNIAYLIYTSGTTGVPKGVAVSHDNVAQLVESLHADLPE--GGVWAQWHSLVFDVSVHEI 1732 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPESV +SPD+LH+LL+ E V+VL QTPSA GMLSPEGL+ST L+VAG Sbjct: 1733 WGALLHGGRLVVVPESVAASPDELHDLLVAEGVTVLSQTPSAVGMLSPEGLDSTALVVAG 1792 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP E+VDRWAPGRVMINAYGPTEAT+YAAMS PL LFVLD+W Sbjct: 1793 EACPVEIVDRWAPGRVMINAYGPTEATVYAAMSTPLQPGTGSAPIGSPVPRAALFVLDRW 1852 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRPAP GVVGELY+AGHGVATGY R LTASRFVACPFG G RMYRTGDLVRW DGQ Sbjct: 1853 LRPAPPGVVGELYIAGHGVATGYARRSGLTASRFVACPFGGPGARMYRTGDLVRWNQDGQ 1912 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 LEYLGRADEQVK+RGYRIELGE+QAALA LDGV+QA VIAREDRPGDKRLVGYITGTADP Sbjct: 1913 LEYLGRADEQVKLRGYRIELGEVQAALAGLDGVEQAAVIAREDRPGDKRLVGYITGTADP 1972 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 +R LAE LPAYMVP AVVVLD +PLTVNGKLD+RALPAPEYR +Y AP+ P E+ Sbjct: 1973 VGIRIQLAERLPAYMVPAAVVVLDALPLTVNGKLDKRALPAPEYRKRGGEYIAPTNPTEE 2032 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA 581 +A ++A+VLG+ERV +DDSFF+LGGDS+ +M+V+A A Sbjct: 2033 TVAGIFARVLGMERVSIDDSFFELGGDSLSAMRVIAEINTA 2073 >tr|D5P2M5|D5P2M5_9MYCO Tax_Id=525368 SubName: Full=Linear gramicidin synthetase subunit C; EC=5.1.1.-;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 2548 Score = 3496 bits (9065), Expect = 0.0 Identities = 1785/2561 (69%), Positives = 2051/2561 (80%), Gaps = 28/2561 (1%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R LLS DLLD EHD+++ WGNRAVLT P V+IPALFA+QV R P+A AL RS Sbjct: 7 RRLLSIDLLDGGEHDRLDEWGNRAVLTAPATGAVSIPALFAKQVARVPEAPALTFEGRSL 66 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 TY+ELDEA+NRLAH+LA+HGA+PG VA L+ RS EAI+SIL+VLKTGAAYLP+DPA P Sbjct: 67 TYQELDEAANRLAHLLADHGARPGECVALLLSRSAEAIVSILAVLKTGAAYLPIDPAVPA 126 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMT 187 AR+ FM+ DA PVAA+TTA+LR+RLD +DL V+D+ DPA+ +PS AL GP P+D+AYM Sbjct: 127 ARMEFMLGDAAPVAAVTTAELRARLDGFDLLVVDVDDPAVADQPSSALPGPAPEDIAYMI 186 Query: 188 YTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHG 247 YTSGTTG PK VAVTH NVTQL+ L ADLP VWSQWHSLVFDVSVWEIWG LLHG Sbjct: 187 YTSGTTGTPKGVAVTHQNVTQLLKKLPADLPKAG--VWSQWHSLVFDVSVWEIWGPLLHG 244 Query: 248 GRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAGEACPTEL 307 GRLVVVPESV SPD+LH LLI EKV+VLCQTPSA GMLSP+GL++T LIVAGEACP+E+ Sbjct: 245 GRLVVVPESVAGSPDELHALLIAEKVTVLCQTPSAVGMLSPDGLDATALIVAGEACPSEV 304 Query: 308 VDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEG 367 VDRWAPGRVMINAYGPTE T+YA+MS L LFVLDKWLRPAPEG Sbjct: 305 VDRWAPGRVMINAYGPTEGTVYASMSSALKAESGAPPIGSPVPGAALFVLDKWLRPAPEG 364 Query: 368 VVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRA 427 VVGELY+AG GVA+GY+ RP LTASRF+ACPFG G RMYRTGDLVRWG DGQL+YLGRA Sbjct: 365 VVGELYIAGRGVASGYVRRPGLTASRFIACPFGAPGTRMYRTGDLVRWGVDGQLQYLGRA 424 Query: 428 DEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPAQLRTAL 487 DEQVKIRGYRIELGEIQ ALA LDGV+QAVVIAREDRPGDKRLVGYITGTADPA++RT L Sbjct: 425 DEQVKIRGYRIELGEIQTALAALDGVEQAVVIAREDRPGDKRLVGYITGTADPAEIRTQL 484 Query: 488 AESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYA 547 LP YMVP AVVVLD +PLTVNGKLD+RALPAPEY+ +YRAP+T E+ L +YA Sbjct: 485 GRRLPGYMVPAAVVVLDALPLTVNGKLDKRALPAPEYQKTNGEYRAPTTAVEETLTAIYA 544 Query: 548 QVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXX 607 QVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+FVEQT Sbjct: 545 QVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVVCRPRDVFVEQTVARLARVAGVAS 604 Query: 608 ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHA 667 + VVDEG+GPVVATPIMRWL++VDGPT QFNQT++ QAPAGVT DDV+V+LQ+LLDRHA Sbjct: 605 DEDVVDEGIGPVVATPIMRWLQQVDGPTDQFNQTMVVQAPAGVTGDDVLVVLQSLLDRHA 664 Query: 668 TLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSA 727 TLR+RV+D + WS+ VPEAGAV A CL TVDAL+D LV AR++L+PAAG M+ A Sbjct: 665 TLRMRVDD--DGAGGWSMQVPEAGAVEAAACLHTVDALSDASLVAARSQLNPAAGTMLRA 722 Query: 728 VWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLA 787 VW T+QL LMIHHLAVDGVSWRILLEDLNIAWAQH +GQ + LP GGTSFARWSA+L Sbjct: 723 VWAESTAQLALMIHHLAVDGVSWRILLEDLNIAWAQHHSGQPVALPTGGTSFARWSAMLE 782 Query: 788 EHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAA 847 E+A+ V A+AWR V + P LP V+PD DTY TA QLS SLDV+TTR LLGEVPAA Sbjct: 783 EYAQRPEVVAQAEAWREVAATPALLPAVRPDVDTYETAKQLSVSLDVDTTRMLLGEVPAA 842 Query: 848 FRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPV 907 F AGVQDILL+AFGLAW F+ + PIG+DVEGHGR++EL VDLSRTVGWFTTKYPV Sbjct: 843 FHAGVQDILLIAFGLAWARFVG-TGAPIGIDVEGHGRHEELGPHVDLSRTVGWFTTKYPV 901 Query: 908 ALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGGSDPTIGF 967 AL V L W QV+AGD +LG +VK KEQLR+LP+ LTYGLLRY+N EVDL GSDP IGF Sbjct: 902 ALAVGELDWAQVMAGDRSLGVLVKKAKEQLRALPDPLTYGLLRYMNAEVDLDGSDPVIGF 961 Query: 968 NYLGRLGAGAGELSEELWRIDQXXXXXXXXXXX-VPMPLMHTVELNAGTIDTDNGPSLRA 1026 NYLGRLGA A +L E+WRI Q +PMPLMHTV+LNAGT+DT+ GP L+A Sbjct: 962 NYLGRLGAAA-DLPGEMWRISQDSLSFTGAASAALPMPLMHTVDLNAGTMDTEAGPHLQA 1020 Query: 1027 SWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQR 1086 +WTWAPSA D EQ +RLS+LWFEALAGICAHVR GGGGLTPSD+APA+L Q+Q+D+L Q+ Sbjct: 1021 NWTWAPSALDHEQVSRLSQLWFEALAGICAHVRSGGGGLTPSDIAPAQLDQQQLDDLCQQ 1080 Query: 1087 YDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHP 1146 Y V DVLPLTP+QQGLLFH++FA GDDVYAVQL IT+TG LD HRLR+AVH VV RHP Sbjct: 1081 YAVADVLPLTPLQQGLLFHASFANDPGDDVYAVQLGITVTGDLDPHRLREAVHAVVNRHP 1140 Query: 1147 NLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPT 1206 NLAARF QFG+PVQV+ ADP +AWRY+ L +DL PD +IEQLCAAER+AV DL RP Sbjct: 1141 NLAARFCPQFGQPVQVIPADPAMAWRYIQLGAEDLDPDEKIEQLCAAERAAVSDLANRPA 1200 Query: 1207 FRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXX 1266 FRAALIRT+ N+HRFVLT HHIV+DGWSLPILL+EI Y+G RLPA A YR+++ WL Sbjct: 1201 FRAALIRTADNRHRFVLTNHHIVMDGWSLPILLREILTSYYGERLPAPASYRSYLTWLAA 1260 Query: 1267 XXXXXXXXXWREVLDGFETPTLVAPPG--VPGPRGIESYRVSAETTRALGELARSQHTTI 1324 W EVL GF+TPTLV PP G RG+ESYR+ AETTRALGELARS HTTI Sbjct: 1261 QDRTAARAAWGEVLAGFDTPTLVGPPARLSVGRRGVESYRLPAETTRALGELARSCHTTI 1320 Query: 1325 NTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTV 1384 NTVLQAAW QLLMR+TGQ DVAFGTAVSGRPADLAGAESMVGLLINTVP+RA ++A TTV Sbjct: 1321 NTVLQAAWAQLLMRVTGQYDVAFGTAVSGRPADLAGAESMVGLLINTVPVRAHITAATTV 1380 Query: 1385 GDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVT 1444 +LL+QLQ+ HN+TLEHEHLALN+IH V+GH+ LFDTLFLYE+YPIDTS +G ELA+T Sbjct: 1381 AELLQQLQNAHNNTLEHEHLALNEIHRVTGHDLLFDTLFLYENYPIDTSVPLGFHELAIT 1440 Query: 1445 EFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRL 1504 + NREYNHYPL+VMALPG ELGLRVE+DTSVFD + IE++I+RF+R+L AM D ++RL Sbjct: 1441 DVTNREYNHYPLAVMALPGRELGLRVEFDTSVFDTAGIESMIERFERVLGAMTADSSQRL 1500 Query: 1505 SSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYG 1564 S+MDV+D ER +LDEW NRAVLT PV + SIP +FA+QV R P+A A+TFEG SL Y Sbjct: 1501 SAMDVLDLGERARLDEWGNRAVLTAPVRAAASIPALFAKQVARVPDAVALTFEGRSLTYR 1560 Query: 1565 ELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARL 1624 ELDEAAN+LA+LLA +GA PG+SVAL+ RSA+AIV+ILAVLKTGAAYLPIDP+VP+AR+ Sbjct: 1561 ELDEAANRLAHLLAEHGARPGESVALLFSRSAEAIVSILAVLKTGAAYLPIDPAVPSARI 1620 Query: 1625 EFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTS 1684 EF+L DA PVAAVTT DLR R DGFDL VV+VD + P+T L PSP+DIAY+IYTS Sbjct: 1621 EFVLSDAAPVAAVTTADLRPRLDGFDLVVVDVDAAPADTRPATALPAPSPEDIAYVIYTS 1680 Query: 1685 GTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRL 1744 GTTGVPKGVA+TH N TQ+L+ L A+LP PG VW+QWHSLVFDVSV EI+GALLHGGRL Sbjct: 1681 GTTGVPKGVAVTHHNATQLLEKLHADLP-DPG-VWAQWHSLVFDVSVHEIFGALLHGGRL 1738 Query: 1745 VIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDR 1804 V+VPES+AGSP DLHALLV+E V VL QTPSAV M+SPEGLE TALVVAGEACP EVV+R Sbjct: 1739 VVVPESVAGSPKDLHALLVAENVTVLSQTPSAVGMLSPEGLESTALVVAGEACPPEVVER 1798 Query: 1805 WAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVG 1864 WA RVMINAYGPTE T+YAA+SAPL+ + PIGSPVP A FVLD+WLRP P GVVG Sbjct: 1799 WAPGRVMINAYGPTEGTVYAAMSAPLNADAG-APIGSPVPGAALFVLDKWLRPAPEGVVG 1857 Query: 1865 ELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQ 1924 ELY+A LT +RFVACPFG PG+RMYRTGDLVRWG DGQLQYLGR DEQ Sbjct: 1858 ELYIAGRGVACGYARRSGLTASRFVACPFGAPGSRMYRTGDLVRWGADGQLQYLGRVDEQ 1917 Query: 1925 VKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNR 1984 VKIRGYRIELGEIQAAL+ +DGV+QA VIAREDRPGDKRLVGYITGTADPA R++L R Sbjct: 1918 VKIRGYRIELGEIQAALAGLDGVEQAAVIAREDRPGDKRLVGYITGTADPAEVRAQLGER 1977 Query: 1985 LPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSA-QRYRAPETETEKTLAGIFAHVL 2043 LPAYMVP AVV L+ LPLTVNGKLD+RALPAPE++ A YR P T E+TLA IFA VL Sbjct: 1978 LPAYMVPVAVVVLDALPLTVNGKLDKRALPAPEFKKAGGEYRGPATAVEETLADIFAGVL 2037 Query: 2044 GVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 G++R AMRV A VNTALDA+LSVRTLFEAPTV +L E DAG Sbjct: 2038 GLQRVSVEDSFFDVGGDSLSAMRVIAEVNTALDANLSVRTLFEAPTVRRLGQRAERDAGG 2097 Query: 2104 RTD----RVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXXXXXXXXGAVQTVLLTGAT 2159 + SFA+VHG D T+V A DLTLDKFI V+TVLLTGAT Sbjct: 2098 ADELEAGGPSFASVHGRDATQVFASDLTLDKFIDAATLGNAPALPGPSSEVRTVLLTGAT 2157 Query: 2160 GFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDT-DPLLRKHFNELATER 2218 GFLGRYL L+WL QL VD K+ICLVR SDE+AR+RLE TFDT DP L ++F ELA + Sbjct: 2158 GFLGRYLALQWLEQLELVDGKLICLVRAGSDEEARQRLEKTFDTGDPKLLRYFQELAADH 2217 Query: 2219 LQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAELIRF 2278 L+VVAGDKG NLGLDE TWQRLA++VDLIVDSAA VN VLPYSELFGPNV GTAELIR Sbjct: 2218 LEVVAGDKGAANLGLDEPTWQRLADTVDLIVDSAALVNGVLPYSELFGPNVAGTAELIRV 2277 Query: 2279 ALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLL 2338 ALT+KLKP+ +VSTSDVGRQI+P+ FTE ADIR +S RK++ YANGYGNSKWAGEVLL Sbjct: 2278 ALTTKLKPYAYVSTSDVGRQIDPAAFTEDADIREISPIRKVDGSYANGYGNSKWAGEVLL 2337 Query: 2339 REAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGDNGE 2398 REAHD CGLPV+VFRS MI+ D +YAGQ N++D +RMVLS+VATG+AP SFYQ G Sbjct: 2338 REAHDLCGLPVSVFRSDMILSDTSYAGQFNLSDMFTRMVLSLVATGIAPRSFYQLDAEGN 2397 Query: 2399 RQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYIDWLI 2458 RQR+HFD LPV+FVA+A+T LG QV GFETYHVMNPHDDGIGID Y+DWLI Sbjct: 2398 RQRSHFDALPVEFVAEAVTTLGAQV--------VEGFETYHVMNPHDDGIGIDEYVDWLI 2449 Query: 2459 EAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRGSFA 2518 EAGYPIERI+DFGEWL+RFEAAL+ L ++QR++SVLQML + +LQ P P GSFA Sbjct: 2450 EAGYPIERIDDFGEWLRRFEAALRELPERQRKHSVLQMLQV--PGYNQLQAPEPATGSFA 2507 Query: 2519 PADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 P DRF+AAV++A IG + +IPHV+ VIVKYVTDLQL+GLL Sbjct: 2508 PTDRFRAAVQEAKIGADNDIPHVSPPVIVKYVTDLQLVGLL 2548 Score = 801 bits (2068), Expect = 0.0 Identities = 409/581 (70%), Positives = 466/581 (80%), Gaps = 4/581 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+ S R L + D+LD E +++ WGNRAVLT P +IPALFA+QV R PDAVAL Sbjct: 1492 MTADSSQR-LSAMDVLDLGERARLDEWGNRAVLTAPVRAAASIPALFAKQVARVPDAVAL 1550 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS TYRELDEA+NRLAH+LAEHGA+PG +VA L RS EAI+SIL+VLKTGAAYLP Sbjct: 1551 TFEGRSLTYRELDEAANRLAHLLAEHGARPGESVALLFSRSAEAIVSILAVLKTGAAYLP 1610 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P ARI F++SDA PVAA+TTADLR RLD +DL V+D+ D RP+ AL P P Sbjct: 1611 IDPAVPSARIEFVLSDAAPVAAVTTADLRPRLDGFDLVVVDVDAAPADTRPATALPAPSP 1670 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +D+AY+ YTSGTTGVPK VAVTHHN TQL+ LHADLP PG VW+QWHSLVFDVSV EI Sbjct: 1671 EDIAYVIYTSGTTGVPKGVAVTHHNATQLLEKLHADLPD-PG-VWAQWHSLVFDVSVHEI 1728 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALLHGGRLVVVPESV SP DLH LL+ E V+VL QTPSA GMLSPEGLEST L+VAG Sbjct: 1729 FGALLHGGRLVVVPESVAGSPKDLHALLVAENVTVLSQTPSAVGMLSPEGLESTALVVAG 1788 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP E+V+RWAPGRVMINAYGPTE T+YAAMS PL LFVLDKW Sbjct: 1789 EACPPEVVERWAPGRVMINAYGPTEGTVYAAMSAPL-NADAGAPIGSPVPGAALFVLDKW 1847 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRPAPEGVVGELY+AG GVA GY R LTASRFVACPFG G RMYRTGDLVRWG+DGQ Sbjct: 1848 LRPAPEGVVGELYIAGRGVACGYARRSGLTASRFVACPFGAPGSRMYRTGDLVRWGADGQ 1907 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L+YLGR DEQVKIRGYRIELGEIQAALA LDGV+QA VIAREDRPGDKRLVGYITGTADP Sbjct: 1908 LQYLGRVDEQVKIRGYRIELGEIQAALAGLDGVEQAAVIAREDRPGDKRLVGYITGTADP 1967 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A++R L E LPAYMVP AVVVLD +PLTVNGKLD+RALPAPE++ A +YR P+T E+ Sbjct: 1968 AEVRAQLGERLPAYMVPVAVVVLDALPLTVNGKLDKRALPAPEFKKAGGEYRGPATAVEE 2027 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA 581 LAD++A VLG++RV V+DSFFD+GGDS+ +M+V+A A Sbjct: 2028 TLADIFAGVLGLQRVSVEDSFFDVGGDSLSAMRVIAEVNTA 2068 >tr|B1MDS4|B1MDS4_MYCA9 Tax_Id=561007 SubName: Full=Probable peptide synthetase NRP;[Mycobacterium abscessus] Length = 2557 Score = 3220 bits (8349), Expect = 0.0 Identities = 1630/2577 (63%), Positives = 1943/2577 (75%), Gaps = 38/2577 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M+ +PS RTL S DLLD+DEH Q+ WGN+AVL + T +IPA+FA QV P+A+AL Sbjct: 1 MSVDPS-RTLSSLDLLDDDEHAQLATWGNQAVLKECPDTMPSIPAVFARQVECTPEALAL 59 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 +S TYRELDEA+NRL+H+L GA PG VA L PRS EAI++IL+VLK+GAAYLP Sbjct: 60 TFDGQSMTYRELDEAANRLSHLLVGAGAGPGQFVALLFPRSTEAIVAILAVLKSGAAYLP 119 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P RI FM++DA PVAA+TTA L RL + V+D+ DPA+ +P A P P Sbjct: 120 IDPALPTTRIEFMLTDAAPVAAVTTAVLAHRLHGLGVPVLDVDDPAVCTQPCTAPPMPSP 179 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +DLA++ YTSGTTGVPK VAVT NV QL L + PGQVW+Q+HS FD SVWEI Sbjct: 180 EDLAHLIYTSGTTGVPKGVAVTQRNVVQLFDRLDIGVELAPGQVWTQFHSYAFDFSVWEI 239 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVP+SV +P+D H+LL+ E+V+V+ QTPSAAG+LSP+GLE+T L++ Sbjct: 240 WGALLHGGRLVVVPDSVARTPEDFHDLLMGERVTVMSQTPSAAGVLSPDGLEATALVIGA 299 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXL--FVLD 358 E CP ELVDRWAPGRVM+N YGPTE T++A S PL FVLD Sbjct: 300 EPCPPELVDRWAPGRVMVNVYGPTETTMWACKSAPLSAGSEGHGVPIGSPVAHAASFVLD 359 Query: 359 KWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSD 418 +WLRP P+GV+GELY+AG GV +GY R LT +RFVACPFG G+RMYRTGDLV WG+D Sbjct: 360 RWLRPVPDGVIGELYLAGAGVGSGYWRRTALTGARFVACPFGMPGDRMYRTGDLVSWGAD 419 Query: 419 GQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA 478 GQL+YLGRADEQ+KIRGYRIELGEIQAAL +LDGV QA VI REDRPGDKR+VGYITG A Sbjct: 420 GQLQYLGRADEQIKIRGYRIELGEIQAALVRLDGVRQAAVIVREDRPGDKRIVGYITGGA 479 Query: 479 DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPA 538 DP R ALAE LPAYMVP AVV L T+P+TVNGKLD++ LPAPEY D+RAPSTP Sbjct: 480 DPVGARAALAEQLPAYMVPVAVVALQTLPVTVNGKLDKQGLPAPEYSGV--DFRAPSTPV 537 Query: 539 EQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXX 598 E+ LA +YAQVLGV+RVG DDSFFDLGGDSIL+MQV RARAAG+ CRPRDIFVEQT Sbjct: 538 EEALAGIYAQVLGVDRVGADDSFFDLGGDSILAMQVAGRARAAGVLCRPRDIFVEQTVAR 597 Query: 599 XXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVV 657 E VD+G+GPV TPIM WL V GP +FNQTV+ QAPAG E D+VV Sbjct: 598 LSRVVTLAENEIRNVDDGIGPVAPTPIMHWLHSVPGPVERFNQTVVLQAPAGAAEADIVV 657 Query: 658 ILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRL 717 +LQALLD H TLRL E+ WSL VPE GAV AR C+RTV+AL+D+ + A +RL Sbjct: 658 LLQALLDHHGTLRLHAENNDGG---WSLRVPEKGAVDARACIRTVEALSDEAVEAACSRL 714 Query: 718 DPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGT 777 DP AGAM+SA+W +L L+IHHLAVDGVSWRILLEDLN+AWAQ +G + L GT Sbjct: 715 DPGAGAMLSALWAPAEGKLALVIHHLAVDGVSWRILLEDLNVAWAQRRSGLDVALSGAGT 774 Query: 778 SFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETT 837 SFARW++LL E A + V + AD WR+V++VP ALP V+P DTY AG LS +LD + T Sbjct: 775 SFARWASLLREQALSAGVVESADVWRSVSAVPPALPVVRPGVDTYAVAGTLSVALDADVT 834 Query: 838 RQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRT 897 R LLGEVPAAF AGVQD+LL+AF LAW EFL PIG+D+EGHGR +ELA+D+DLSRT Sbjct: 835 RMLLGEVPAAFHAGVQDVLLIAFALAWNEFLGAGGAPIGIDLEGHGRAEELAADIDLSRT 894 Query: 898 VGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVD 957 VGWFT KYP AL+V +L W QV GD+ALG +VK+VKEQLR LP+ L+YGLLRYLNPEV Sbjct: 895 VGWFTAKYPAALSVGDLSWAQVSGGDSALGLVVKSVKEQLRGLPDPLSYGLLRYLNPEVA 954 Query: 958 LGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTID 1017 L SD IGFNYLGRLGAGA E SE++W I VPMP+ HTVELNAG ++ Sbjct: 955 LPHSDSAIGFNYLGRLGAGATEASEDIWTISHEGLSWTSASSTVPMPMAHTVELNAGILE 1014 Query: 1018 T--DNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARL 1075 + ++GP L+A WTWAPS D Q RLSRLWFEAL GIC HVR GGGGLTPSD+ PARL Sbjct: 1015 SSVESGPRLQAVWTWAPSLVDAIQVQRLSRLWFEALVGICTHVRTGGGGLTPSDILPARL 1074 Query: 1076 TQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGD--------DVYAVQLDITITG 1127 TQ ++DEL++ V DVLPLTPVQQGLLFHS A D+YAVQL++T+TG Sbjct: 1075 TQGELDELTKCLRVADVLPLTPVQQGLLFHSAIAARADSAAAGTALADIYAVQLNLTMTG 1134 Query: 1128 VLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEI 1187 +D RL +A+H VV RHPNL ARF +FGEPVQV+ ADPMI W+ + + E+ Sbjct: 1135 AVDPRRLYNAMHAVVKRHPNLVARFCTRFGEPVQVIPADPMICWQQTEFESTE-----EL 1189 Query: 1188 EQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYF 1247 E+ CAAER A CDL + TFR+AL+RT G++HRF+LTFHH+VIDGWSLPILL+EIFA YF Sbjct: 1190 ERFCAAERVAACDLAGKSTFRSALVRTGGDKHRFILTFHHVVIDGWSLPILLREIFAIYF 1249 Query: 1248 GHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSA 1307 G L A YR FV+WL WR+ L+GFE PTLVAP VPG RG+ SYR+SA Sbjct: 1250 GQALAPAPSYRGFVSWLAQQDREAARAAWRKALEGFEAPTLVAPRSVPGSRGVASYRISA 1309 Query: 1308 ETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGL 1367 ETTRALG+LARSQHTT++TVL+AAW QLLM TG DVAFGT VSGRPA L GA+S+VGL Sbjct: 1310 ETTRALGDLARSQHTTVSTVLRAAWAQLLMVQTGAHDVAFGTVVSGRPALLTGADSVVGL 1369 Query: 1368 LINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYES 1427 LINTVP+RA+ +A TTV DLLR +QS HND LEHEHLALN+IHH++GH++LFDTLFLYE+ Sbjct: 1370 LINTVPVRARATATTTVADLLRDMQSIHNDLLEHEHLALNEIHHLAGHDRLFDTLFLYEN 1429 Query: 1428 YPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLID 1487 YP+D S FMG EL +TEF +REYNHYPLSVMALPGHELG+R+EYDT FDV++I L+ Sbjct: 1430 YPVDVSTFMGTHELGITEFTSREYNHYPLSVMALPGHELGIRIEYDTDAFDVADIGALVQ 1489 Query: 1488 RFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVER 1547 R +R+L AM PARR+ S+DV++ ER +LD W NRAVL + SIPEVFARQV+R Sbjct: 1490 RLRRILGAMTAAPARRVLSIDVLEVAERGRLDSWGNRAVLACATAASSSIPEVFARQVDR 1549 Query: 1548 DPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLK 1607 P+A A+TF+G S+ Y ELD AAN+LA LLA GA PG+S+ALMVPRS DAIVA+LAVLK Sbjct: 1550 APQAVALTFQGRSMTYRELDHAANRLAQLLASRGAGPGESIALMVPRSDDAIVALLAVLK 1609 Query: 1608 TGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPST 1667 TGAAYLPIDP+VP ARLEFML DA P+A TT +LR R G + V+ +D+ V+ + Sbjct: 1610 TGAAYLPIDPAVPVARLEFMLADAAPIAVATTAELRQRLAGSSIPVLVIDEHVVDEPAAV 1669 Query: 1668 TLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVF 1727 +L P PDDIAY IYTSGTTG PKGVA+TH NVTQ+L+TLP LPAGPG VWSQWHS+VF Sbjct: 1670 SLQAPRPDDIAYTIYTSGTTGTPKGVAVTHRNVTQLLETLPVGLPAGPGQVWSQWHSMVF 1729 Query: 1728 DVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG 1787 DVSVWE+WGALLHG RL++VPE++AGSP LH LLV+E V+VL+QTPSA+ M+ +G++ Sbjct: 1730 DVSVWEVWGALLHGARLMVVPEAVAGSPQHLHDLLVTEKVSVLHQTPSAIGMLDWDGVDD 1789 Query: 1788 TALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGA 1847 A+VVAGE CP EVVDRWA R+M+NAYGPTE+TIYAAIS PLSP + VPIGSPV GA Sbjct: 1790 MAVVVAGEPCPPEVVDRWAPGRLMLNAYGPTEATIYAAISMPLSPKTSPVPIGSPVRGGA 1849 Query: 1848 TFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLV 1907 TFVLD WLRPVPPGVVGELYLA LTG+RFVACPFG PG RMYRTGDL Sbjct: 1850 TFVLDGWLRPVPPGVVGELYLAGSGVGVGYVHRSGLTGSRFVACPFGRPGVRMYRTGDLA 1909 Query: 1908 RWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGY 1967 R+ +DGQLQYLGR DEQVKIRGYRIEL EI++AL+++DGV+ A VI REDRPGDKRLVGY Sbjct: 1910 RYSEDGQLQYLGRTDEQVKIRGYRIELDEIRSALAELDGVEHAAVIVREDRPGDKRLVGY 1969 Query: 1968 ITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAP 2027 +TGTADP R+ L RLP YMVPAAVV ++ +PLT+NGKLD+R+LPAP Y A RYR P Sbjct: 1970 VTGTADPTMLRTLLGERLPQYMVPAAVVAVDAIPLTINGKLDKRSLPAPVYHDAARYREP 2029 Query: 2028 ETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEA 2087 + E+T+A I+AH LG+ER AMRV AA+NTALD DL V T+F+A Sbjct: 2030 VSPVERTIADIYAHTLGLERIGVEDSFFDVGGDSISAMRVVAAINTALDVDLEVWTIFDA 2089 Query: 2088 PTVAKLSLH----VEHDAGERTDRVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXXXX 2143 P+V LS V + R S A+VHG VT+V A DLTLDKF+ Sbjct: 2090 PSVRSLSARLNGAVSASPIAESSRTSCASVHGRGVTQVMATDLTLDKFVDVTALIANRSR 2149 Query: 2144 XXXXGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDT 2203 G V+ +LLTGATGFLGR+L+L WLR++ + CLVRG S E+AR RLE +FD+ Sbjct: 2150 RHPRGDVREILLTGATGFLGRHLVLHWLREMEHAGGTLTCLVRGSSHEEARSRLEKSFDS 2209 Query: 2204 -DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYS 2262 DP L F LA +RL+VVAGDKG+P+LGL+ QTW+ LAESVDL+VDSAAFVNSVLPY Sbjct: 2210 GDPGLMALFRRLAADRLKVVAGDKGEPHLGLEPQTWEHLAESVDLVVDSAAFVNSVLPYE 2269 Query: 2263 ELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVG 2322 ELF PNVVGTAELIR ALT+KLKP+ FVSTSDVGRQ++ S+FTE ADIR +S +R ++ G Sbjct: 2270 ELFRPNVVGTAELIRLALTAKLKPYTFVSTSDVGRQVDRSKFTEVADIREISPSRVLDAG 2329 Query: 2323 YANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVA 2382 YANGY NSKWA EVLLREAHD GLPVAVFRS M+M D +YAGQLN+ DT+SRMVLSI+A Sbjct: 2330 YANGYANSKWAAEVLLREAHDMFGLPVAVFRSSMVMADTSYAGQLNMADTISRMVLSIMA 2389 Query: 2383 TGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMN 2442 TGVAP SFYQ +G RQRAHFDGLPV+FVA+AI LG Q GFETYHVMN Sbjct: 2390 TGVAPESFYQLDMHGNRQRAHFDGLPVEFVAEAIATLGSQ--------ATDGFETYHVMN 2441 Query: 2443 PHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQ 2502 PHDDG+GID ++DWL+EAG+PIER+ +FG WLQRFEA L+ L + QRQNSVLQML +LKQ Sbjct: 2442 PHDDGVGIDQFVDWLVEAGHPIERVGNFGVWLQRFEAGLRALPNPQRQNSVLQMLMVLKQ 2501 Query: 2503 QAGELQPPVPTRGSFAPADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 G+L+ P PT GS+APADRFQAAVR A IG + +IPH++ +I+KYVTDLQ+LGLL Sbjct: 2502 H-GQLRAPAPTCGSYAPADRFQAAVRRAKIGSDQDIPHISAPIILKYVTDLQMLGLL 2557 >tr|A0QYM8|A0QYM8_MYCS2 Tax_Id=246196 SubName: Full=Linear gramicidin synthetase subunit C; EC=5.1.1.-;[Mycobacterium smegmatis] Length = 2574 Score = 3105 bits (8051), Expect = 0.0 Identities = 1595/2583 (61%), Positives = 1905/2583 (73%), Gaps = 44/2583 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M +P TR LLS DLLD+DEHD+++ WGNR+ LT P TIP LF+ QV R P A AL Sbjct: 1 MVGDP-TRRLLSIDLLDDDEHDRLDDWGNRSALTRPAAQQKTIPQLFSAQVTRTPTAHAL 59 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V G+R +TYRELDEA++RLA L G+ PG VA L+PRS EAI++IL+VLK+GAAYLP Sbjct: 60 VCGERVFTYRELDEATDRLAMRLTRSGSGPGQCVALLLPRSAEAIIAILAVLKSGAAYLP 119 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +D AHPDAR+ FM+ DAKPVAA+TT+ L +RL + ++D+ A D S + P P Sbjct: 120 MDTAHPDARLRFMLHDAKPVAAVTTSALHTRLTGTGIPLLDI--DACDTGASAPIRPPVP 177 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DDLAY+TYTSGTTGVPKAVAVTH NVTQL+ H +LP+ PGQVWSQWHSLVFDVSVWEI Sbjct: 178 DDLAYLTYTSGTTGVPKAVAVTHRNVTQLLECPHPELPASPGQVWSQWHSLVFDVSVWEI 237 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 GALLHG RLVVVPES+ SSP +L+ LL+ E+V+VLCQTPS+AGMLS EGL+ T L+VAG Sbjct: 238 CGALLHGNRLVVVPESIASSPHELNALLVRERVTVLCQTPSSAGMLSAEGLDRTALVVAG 297 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP +LV RWAPGRVM+NAYGPTEAT+YAAMS PL FVLDK+ Sbjct: 298 EACPADLVQRWAPGRVMLNAYGPTEATVYAAMSSPLSSDADPVPIGRPVPHAAAFVLDKF 357 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP +GV+GELY+AG GVA GY R LTASRFVACPFG G+RMYRTGDLVRW DG Sbjct: 358 LRPVLDGVIGELYIAGAGVAVGYARRSALTASRFVACPFGTPGQRMYRTGDLVRWDDDGH 417 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L YLGR DEQVKI GYRIELGE+QAALA LDGVDQAVV REDRPGD+RLVGYI G ADP Sbjct: 418 LVYLGRCDEQVKIHGYRIELGEVQAALAGLDGVDQAVVTVREDRPGDQRLVGYIIGAADP 477 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 + R ALAE LPAYMVP AVVVLD++PLTVNGKLD+RALPAP+YR A +RAP++ E+ Sbjct: 478 SASRRALAERLPAYMVPAAVVVLDSLPLTVNGKLDKRALPAPDYRGDAGSFRAPTSDVER 537 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXX 600 IL D+Y++VLGV+RVGVDDSFF LGGDSILSM+VVA+AR G++ RPRD+FVEQT Sbjct: 538 ILTDIYSEVLGVDRVGVDDSFFALGGDSILSMRVVAQARMQGLRLRPRDVFVEQTVARLA 597 Query: 601 XXXXXXXESHVVDEGV-GPVVATPIMRWLREVDGPTGQFNQTVITQAPA---GVTEDDVV 656 E V PV ATP+MRWL+ VDG QF+Q ++ QAPA G DVV Sbjct: 598 ATATLVSGQREPGEDVTAPVTATPMMRWLQTVDGQVDQFHQAMVLQAPADAAGCEFADVV 657 Query: 657 VILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNR 716 +LQ LLD HA LRL D S V E GAV A +C+++VD L + L +AR+R Sbjct: 658 DVLQDLLDHHAALRLCASG-----DGPSAPVLEVGAVRAADCVQSVDTLCAETLAKARSR 712 Query: 717 LDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGG 776 L+PA G ++SA+WV T QLVLMIHH+ VDGVSWRILLEDLNIAWAQ Q +ELPA G Sbjct: 713 LNPAEGRLLSALWVPHTHQLVLMIHHIGVDGVSWRILLEDLNIAWAQRRAHQRVELPAEG 772 Query: 777 TSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVET 836 TS A WSALL +HA + V A AW+ V S+ LP QP DTY TAG LS SLD ET Sbjct: 773 TSLAHWSALLQKHAYSPEVVAQAGAWQKVLSIATPLPETQPAVDTYATAGHLSVSLDSET 832 Query: 837 TRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELAS----DV 892 TRQLLG+VPAAF AGV DI+L+A+ LAW EF I +DVEGHGR +EL D+ Sbjct: 833 TRQLLGDVPAAFHAGVGDIMLIAYALAWNEFRGGGSASITIDVEGHGRDEELGDVFGEDI 892 Query: 893 DLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYL 952 DLSRTVGWFTTKYPVA+TV L W+ V G ALG ++K+ KEQL SLP TYGLLR+L Sbjct: 893 DLSRTVGWFTTKYPVAITVAPLRWDLVRDGAPALGAMIKSAKEQLHSLPGTSTYGLLRHL 952 Query: 953 NPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELN 1012 N +VDL G +PTIGFNYLGR+GA L + LWRID VPMPLMHT+ELN Sbjct: 953 NTDVDLSGPEPTIGFNYLGRVGAD--HLGDRLWRIDPDGLALAEVASAVPMPLMHTLELN 1010 Query: 1013 AGTIDTDNG-----PSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTP 1067 AGT+ D+ P+L+A+WTWAPSA DE Q RLS+LWFEAL GICAHVR GGGG TP Sbjct: 1011 AGTLQVDSPAGTPEPALQAAWTWAPSAVDEAQVKRLSQLWFEALTGICAHVRSGGGGWTP 1070 Query: 1068 SDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARG-IGDDVYAVQLDITIT 1126 SD+APA LTQ QID+++++Y V D+LPLTP+QQGL FHS G DVYAVQLDIT+T Sbjct: 1071 SDIAPAVLTQSQIDQIAEQYRVADILPLTPLQQGLFFHSLIGPGEASTDVYAVQLDITVT 1130 Query: 1127 GVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHE 1186 G+LD RL DA+ TV+ RHPNL ARF F PVQ++ DP++AWRY+DLR DD P+ E Sbjct: 1131 GLLDADRLHDALLTVLRRHPNLVARFCGDFDPPVQIIPDDPVMAWRYMDLREDDRPPEVE 1190 Query: 1187 IEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGY 1246 IE+LC AER AVC L +RP FRAALIRT+GNQHRFV+TFHHIV+DGWSLPILL+EIF Y Sbjct: 1191 IEKLCTAERVAVCHLTDRPAFRAALIRTAGNQHRFVMTFHHIVVDGWSLPILLKEIFGAY 1250 Query: 1247 FGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVS 1306 F HRLPA PYR+FV WL W EV+ GF +PT++ PG PGPR +Y V Sbjct: 1251 FEHRLPAPRPYRDFVGWLSAQDHDAARAAWHEVMGGFASPTVLTHPGPPGPRRAHTYHVP 1310 Query: 1307 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVG 1366 AETTRA+G+LARS TT+NTVLQAAW QLLM +TGQ DVAFGTAVSGRPA+LAG++S+VG Sbjct: 1311 AETTRAVGDLARSCRTTVNTVLQAAWAQLLMALTGQHDVAFGTAVSGRPAELAGSDSLVG 1370 Query: 1367 LLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYE 1426 LLINT+P+RA V +V DLL QLQ HN T++HE+++LN+IH ++GH+QLFDTLF+YE Sbjct: 1371 LLINTIPVRANVPPTASVSDLLDQLQRTHNATVDHEYMSLNEIHRITGHDQLFDTLFVYE 1430 Query: 1427 SYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLI 1486 SYP D AF G ELA+T+F RE+NHYPLSV+A+PGHELGLR E+D+ F +IE LI Sbjct: 1431 SYPFDAGAFAGTHELAITDFTTREHNHYPLSVIAIPGHELGLRAEFDSVRFTDDDIEELI 1490 Query: 1487 DRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVE 1546 +RF R+L AMIDDP RR+S++DV+ ER +LD W R L SIPE F+ QV Sbjct: 1491 ERFLRVLAAMIDDPERRVSTIDVLGTSERERLDSWCRRERLRGKGSGSSSIPERFSAQVV 1550 Query: 1547 RDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVL 1606 R P++ AVT GESL Y ELDE A++LANLL ++GA PG VA+M+PR A AIVAILAVL Sbjct: 1551 RTPDSVAVTCGGESLTYAELDETADRLANLLTLHGAGPGTYVAIMLPRCAQAIVAILAVL 1610 Query: 1607 KTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPS 1666 KTGAAYLPIDP +P AR++FML D P+AAVT +LRSRFDGF VVE DDPA+ ++P+ Sbjct: 1611 KTGAAYLPIDPVLPDARVQFMLDDTAPIAAVTNDELRSRFDGFAGVVVEADDPAMSLHPT 1670 Query: 1667 TTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLV 1726 T LL P+ DDIAY+IYTSGTTG PKGVA+TH NVT++ D L G G VW+Q HS Sbjct: 1671 TALLAPAADDIAYVIYTSGTTGRPKGVAVTHHNVTRLFDAPYPGLTFGSGQVWTQCHSTG 1730 Query: 1727 FDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLE 1786 FD SVWEIW ALLHGGRLV+VPES+ SP DLH LLV+E V + QTP+A +S GLE Sbjct: 1731 FDFSVWEIWSALLHGGRLVVVPESVTSSPSDLHELLVTEHVTMFSQTPAAAAALSHTGLE 1790 Query: 1787 GTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGS-DVVPIGSPVPK 1845 LVV GEACP+EVV RWA R MIN YGPTE+T++A+ S PL+P S VPIG+PVP Sbjct: 1791 DLTLVVGGEACPSEVVQRWAPKRTMINGYGPTETTVFASTSEPLNPSSPGDVPIGAPVPG 1850 Query: 1846 GATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGD 1905 A FVLD WLRPVPPGV GE+Y+A +T +RFVACPF G+RMYRTGD Sbjct: 1851 AAVFVLDSWLRPVPPGVAGEVYVAGGGVTVGYVHRPGMTASRFVACPFAADGSRMYRTGD 1910 Query: 1906 LVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLV 1965 L RWG DGQL+YLGRAD+QVKIRG+RIELGEIQ AL+D+DGVDQA V+ RED+PGDKRLV Sbjct: 1911 LARWGTDGQLRYLGRADDQVKIRGFRIELGEIQCALADLDGVDQAAVVVREDQPGDKRLV 1970 Query: 1966 GYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYR 2025 GYITGT DPA AR L + LP YMVPAAV+ L+TLP+TVNGKLD+RALP P Y + + +R Sbjct: 1971 GYITGTMDPAVAREMLADHLPPYMVPAAVLRLDTLPVTVNGKLDQRALPVPGYGNTRIHR 2030 Query: 2026 APETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLF 2085 P T TEK +AG+F VLGVE+ AMR AA+NTALD + V+ L Sbjct: 2031 PPVTRTEKVVAGVFGQVLGVEQVGIDDSFFDLGGDSISAMRCVAAINTALDVGVGVQDLL 2090 Query: 2086 EAPTVAKLSLHVEHDAGERTDRV-----SFAAVHGS-DVTEVHARDLTLDKFIXXXXXXX 2139 +AP V LS +E GE TD + + +VHGS DVTE+ A DLTLDKFI Sbjct: 2091 QAPQVRLLSRQIE-GVGE-TDTLAAGGATVESVHGSADVTEIRAADLTLDKFIDDAALSA 2148 Query: 2140 XXXXXXXXGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEA 2199 ++TVLLTGATGFLGR+L+LEWL++L VD K++CLVR SD +AR RLE Sbjct: 2149 ARNLPRTDAKIRTVLLTGATGFLGRFLVLEWLQRLEPVDGKLVCLVRAASDAEARVRLEK 2208 Query: 2200 TFDT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSV 2258 FD DPLL F +L+T RLQVVAGDK LGLD++TW LA SVDL++DSA FVN + Sbjct: 2209 VFDCGDPLLLNRFRQLSTNRLQVVAGDKSAAALGLDQETWTELAASVDLVIDSAGFVNGI 2268 Query: 2259 LPYSELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRK 2318 LPY E FGPNV GTAE+IRFALT+KLK + +VST+DV +QI+P+ FTE ADIR++S +R+ Sbjct: 2269 LPYREFFGPNVAGTAEVIRFALTTKLKSYAYVSTADVRQQIDPAAFTEDADIRVISPSRQ 2328 Query: 2319 IEVGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVL 2378 ++ GYA+GYGNSKWAGEVLLREAHD CGLPV VFR MI+ D TY+GQLN+ D +RMVL Sbjct: 2329 MDAGYASGYGNSKWAGEVLLREAHDLCGLPVRVFRCDMILTDTTYSGQLNLPDNFTRMVL 2388 Query: 2379 SIVATGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETY 2438 S+V+TG+AP SFYQ + GERQRAH+D LPV FVA+AI+ L + GFETY Sbjct: 2389 SVVSTGLAPASFYQLDNTGERQRAHYDALPVGFVAEAISTL--------SVGAVDGFETY 2440 Query: 2439 HVMNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLT 2498 HVMNPHDDG+G D Y+DWLIEAGYPI RI DF EWL+RFE AL+ L ++QRQ+SVLQ+LT Sbjct: 2441 HVMNPHDDGVGADQYVDWLIEAGYPIRRIADFAEWLRRFETALRSLPERQRQHSVLQILT 2500 Query: 2499 LLKQ--QAGELQPPVPTRGSFAPADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLL 2556 Q +LQ P PT GS+ P DRF+AAVR+ IG EG+IPHVT ++I+KYV DLQ L Sbjct: 2501 ARHDLAQGADLQAPEPTLGSYGPTDRFRAAVREHRIGGEGDIPHVTPQIIIKYVADLQRL 2560 Query: 2557 GLL 2559 GLL Sbjct: 2561 GLL 2563 >tr|D5P396|D5P396_9MYCO Tax_Id=525368 SubName: Full=Linear gramicidin synthetase subunit D; EC=1.-.-.-;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 7454 Score = 2657 bits (6887), Expect = 0.0 Identities = 1365/2107 (64%), Positives = 1609/2107 (76%), Gaps = 18/2107 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P+ RT+ S DLLD E ++E G+RA LT P P++IPA FA QV R PDA AL Sbjct: 5101 MTTDPA-RTVSSVDLLDAAERARLEELGHRAALTAPAAEPLSIPAAFAAQVARTPDAPAL 5159 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G R+WTYRELDEA+NRLAH+LA GA PG TVA L RS EAI++IL+ LKTGAAYLP Sbjct: 5160 GCGARTWTYRELDEAANRLAHLLAGRGAGPGHTVALLFNRSAEAIVAILAALKTGAAYLP 5219 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDPAHP ARIGFM++DA PVAALTTADL RLD++D+AVID+ DPA++ +P+ AL P Sbjct: 5220 VDPAHPAARIGFMLADAAPVAALTTADLADRLDEHDVAVIDVDDPAVETQPATALPAPSA 5279 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +D+AY+ YTSGTTGVPK VAV+H +VT L++++ A LP VWSQWHS FDVSVWEI Sbjct: 5280 EDVAYLIYTSGTTGVPKGVAVSHRSVTGLMASVDARLPDAG--VWSQWHSYGFDVSVWEI 5337 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALL GGRLVVVP++V SP+DLH LL+ E VSVL QTPSAA ML P GLES L+VAG Sbjct: 5338 FGALLRGGRLVVVPDAVVRSPEDLHALLVGEGVSVLSQTPSAAAMLDPAGLESAALVVAG 5397 Query: 301 EACPTELVDRWAP-GRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 EACPT+LVDRWA GRVMINAYGPTEAT+YAA+S PL LFVLD+ Sbjct: 5398 EACPTDLVDRWATSGRVMINAYGPTEATVYAAISAPLTPGSGVVPIGSPVAGAALFVLDE 5457 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 +LRP P GVVGELYVAG G+A GY R LTASRFVACPFG G+RMYRTGDLV WG+DG Sbjct: 5458 YLRPVPPGVVGELYVAGGGLARGYWRRAALTASRFVACPFGGPGDRMYRTGDLVCWGADG 5517 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVKIRGYRIELGEIQAALA+L GV QA V+AREDRPGDKRLVGYITG AD Sbjct: 5518 QLQYLGRADEQVKIRGYRIELGEIQAALAELRGVRQAAVVAREDRPGDKRLVGYITGKAD 5577 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA+LR LA+ LPAYMVP AVV LD +PLT NGKLD RALPAPEY S A+ YRAP TP E Sbjct: 5578 PAELRARLADRLPAYMVPVAVVTLDALPLTPNGKLDARALPAPEY-SDADRYRAPGTPVE 5636 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 +ILA +YAQVLGVER+GVDDSFFDLGGDSI SMQVV RARAAG+ CR RDIFVEQT Sbjct: 5637 EILAGIYAQVLGVERIGVDDSFFDLGGDSISSMQVVTRARAAGLTCRTRDIFVEQTVARL 5696 Query: 600 XXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVI 658 ++ DEG G + ATPI+RWL VDGP +FNQT++ APAGVTE DVV + Sbjct: 5697 ARVVGVADGDADATDEGTGALPATPIIRWLEGVDGPVEEFNQTMVVAAPAGVTEADVVAV 5756 Query: 659 LQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLD 718 LQALLDRHA LRLR++D D W+L VPEAG+V A E LRTVD L++ ++ AR+RLD Sbjct: 5757 LQALLDRHAMLRLRLDD---GADGWALTVPEAGSVDAAERLRTVDDLSEAAVLAARSRLD 5813 Query: 719 PAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTS 778 PA G M+SA+W T QLVL+IHHLAVDGVSWRILLEDLNIAWAQH GQ + LP GGTS Sbjct: 5814 PARGVMLSALWAAGTGQLVLIIHHLAVDGVSWRILLEDLNIAWAQHRGGQPVALPPGGTS 5873 Query: 779 FARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTR 838 FARW+ALLAEHA V A AW+ + + P ALP V+P+ DTY TA LS LDVETTR Sbjct: 5874 FARWAALLAEHAHAPDVAGQAGAWKRIAATPPALPAVRPEIDTYETAEHLSVQLDVETTR 5933 Query: 839 QLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTV 898 LLGE PAAF AG+ DILL+ + LAW EFL D P+G+DVEGHGR++EL + VDLSRTV Sbjct: 5934 TLLGEAPAAFHAGINDILLIGYALAWAEFLETGDAPVGIDVEGHGRHEELGAGVDLSRTV 5993 Query: 899 GWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDL 958 GWFTTKYPVAL+V +PW QV++GD ALG +KA KEQLR+LP+ LTYGLLRYLN +VDL Sbjct: 5994 GWFTTKYPVALSVAEMPWAQVLSGDPALGAALKAAKEQLRALPDPLTYGLLRYLNADVDL 6053 Query: 959 GGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDT 1018 G+DPTIGFNYLGRLG A E+S+ELWRI + VPMPLMHTV+LNAGT DT Sbjct: 6054 DGADPTIGFNYLGRLGGAAAEMSDELWRISRDGSSTTATSTAVPMPLMHTVDLNAGTADT 6113 Query: 1019 DNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQR 1078 + GP L A+WTWAPSA D EQ TRLSRLWFEALAGICAHVR GGGGLTPSDV PARLTQR Sbjct: 6114 EEGPRLHANWTWAPSALDREQVTRLSRLWFEALAGICAHVRSGGGGLTPSDVLPARLTQR 6173 Query: 1079 QIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGD--DVYAVQLDITITGVLDQHRLRD 1136 QIDEL +R + D+LPLTP+Q+GLLFH+T RG D D+Y VQLD++++G LD+ RLRD Sbjct: 6174 QIDELERRTGIADILPLTPLQEGLLFHATTTRGGQDSGDLYVVQLDMSVSGPLDRDRLRD 6233 Query: 1137 AVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERS 1196 AV VV RHP+L A+F +QF EPVQ++ ADP++AWRY++L G PD I +LCAAER+ Sbjct: 6234 AVQAVVDRHPHLVAQFCDQFDEPVQIIPADPVMAWRYVELDG-GTDPDERIRELCAAERA 6292 Query: 1197 AVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP 1256 AVCDL +RP FR A++RT+ N+HR VLT HH+V+DGWS+PIL+ E FA G RL A P Sbjct: 6293 AVCDLADRPAFRVAMVRTAENRHRLVLTIHHVVLDGWSVPILVNETFASLTGQRLAPAPP 6352 Query: 1257 YRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGV--PGPRGIESYRVSAETTRALG 1314 YRNFV WL W EVL GF+TP+LV PP P RG+ + VSAETTRALG Sbjct: 6353 YRNFVTWLADRDLDAARAAWGEVLAGFDTPSLVGPPHAMQPAARGLTTVAVSAETTRALG 6412 Query: 1315 ELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPI 1374 ELARS TT++TVLQAAW QLL +TG DVAFGT VSGR A++AGAESMVGLLINT+P+ Sbjct: 6413 ELARSCQTTVSTVLQAAWAQLLTWLTGNYDVAFGTTVSGRSAEVAGAESMVGLLINTIPV 6472 Query: 1375 RAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSA 1434 RA+++ T+ DLL QLQS HNDTLEHEHL+L++IH ++GHE+LFDTLF YE+YP++TSA Sbjct: 6473 RARITPATSTADLLDQLQSAHNDTLEHEHLSLSEIHRITGHEKLFDTLFAYENYPLETSA 6532 Query: 1435 FMGVQELAVTEFNNREYNHYPLSVM-ALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLL 1493 EL++T+FN E NHYPL++ AL G +GLRVEYD +FD +E L R +R+L Sbjct: 6533 MAVNHELSITDFNVFERNHYPLTMQAALSGDRIGLRVEYDAGLFDEHTVEALTKRLERVL 6592 Query: 1494 EAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPA 1553 AM DPARRLSS+D++D E +LD+ +RAVL++P P SI ++FA QV R P+APA Sbjct: 6593 VAMTADPARRLSSVDLLDGAEHARLDDVGHRAVLSRPAPDPVSITDMFADQVARRPDAPA 6652 Query: 1554 VTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYL 1613 + + S+ Y ELDEAAN+LA+LLA GA PG SVAL+ RSA AIVAILAVLKTGAAYL Sbjct: 6653 IGWADLSMTYRELDEAANRLAHLLAAEGAGPGTSVALLFSRSAQAIVAILAVLKTGAAYL 6712 Query: 1614 PIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPS 1673 PIDP+ P AR+ FML DA PVAAVTT LRSR D D++V++++DP ++ P T L P Sbjct: 6713 PIDPAAPGARIRFMLADAAPVAAVTTAGLRSRLDESDVRVIDIEDPRIDRQPPTALPAPE 6772 Query: 1674 PDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWE 1733 D +AY+IYTSGTTG PKGVA+TH NVT+++ +L A LPA PG VW+Q HS FDVSVWE Sbjct: 6773 ADGVAYLIYTSGTTGAPKGVAVTHRNVTRLIGSLDAGLPA-PG-VWTQCHSYAFDVSVWE 6830 Query: 1734 IWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVA 1793 I+ LL GGR+V+VPE++ SP D ALL+ EGV+VL QTPSAV M+ P GL+ +LV+A Sbjct: 6831 IFAPLLRGGRVVVVPEAVVRSPQDFRALLLDEGVSVLTQTPSAVAMLDPAGLDSVSLVMA 6890 Query: 1794 GEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDE 1853 GEACP EVVDR+A RVM+NAYGPTE+T+ AISAPL+ GS PIGSPVP A FVLD Sbjct: 6891 GEACPPEVVDRFAPGRVMVNAYGPTETTMCVAISAPLAAGSGTPPIGSPVPGAALFVLDG 6950 Query: 1854 WLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDG 1913 WLRPV PGVVGELY+A LTG+RFVACPFGEPGARMYRTGDLV WG DG Sbjct: 6951 WLRPVAPGVVGELYVAGSGVAAGYLGRAGLTGSRFVACPFGEPGARMYRTGDLVFWGADG 7010 Query: 1914 QLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTAD 1973 QL Y+GRADEQVKIRGYRIELGE+QAAL+ +DGVDQAVVIAREDRPGDKRLVGYITGTAD Sbjct: 7011 QLVYVGRADEQVKIRGYRIELGEVQAALARLDGVDQAVVIAREDRPGDKRLVGYITGTAD 7070 Query: 1974 PAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEK 2033 PA AR+ L RLP YMVPAAV+ L+ LPLT NGKLD RALPAPEY + + YRAP TE+ Sbjct: 7071 PAEARTALAGRLPVYMVPAAVLGLDALPLTPNGKLDTRALPAPEY-TGRGYRAPSNATEE 7129 Query: 2034 TLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKL 2093 LAG+FA VLG +R AMR+ A +N L DL+VRTLF+APTV L Sbjct: 7130 ILAGLFAQVLGADRVGVDDSFFDLGGDSISAMRLIATINAHLAVDLAVRTLFDAPTVRDL 7189 Query: 2094 SLHVEHD 2100 S + D Sbjct: 7190 SQRLGTD 7196 Score = 2555 bits (6622), Expect = 0.0 Identities = 1334/2118 (62%), Positives = 1572/2118 (74%), Gaps = 29/2118 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P+ R L S DLLDE EH ++ GNRAVLT P PV+IPALFA QV R P+AVAL Sbjct: 2555 MTVDPA-RPLSSLDLLDEAEHAHLDRIGNRAVLTAPAAAPVSIPALFAAQVARTPEAVAL 2613 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS TYRELDEA+NRLA VLA GA PG +VA L RS EAI++IL+VLK+GAAYLP Sbjct: 2614 ACAGRSMTYRELDEAANRLAGVLAGRGAGPGESVALLFSRSAEAIVAILAVLKSGAAYLP 2673 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P++RIGF++SDA P+A +TTADL RL +D+ VID+ D ID + AL+ P P Sbjct: 2674 IDPALPESRIGFVLSDAAPLAVVTTADLADRLIGHDVPVIDVGD--IDTARAAALTAPGP 2731 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +D+AY+ YTSGTTGVPK VAVTH N TQL++ + A LP VWSQWHSL FDVSV EI Sbjct: 2732 EDIAYLIYTSGTTGVPKGVAVTHRNATQLLARMDAGLPRAG--VWSQWHSLAFDVSVHEI 2789 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALLHGGRLVVVPE+V SP+D H LL+ E VSVL QTPSAA ML PEGL+S L+VAG Sbjct: 2790 FGALLHGGRLVVVPETVARSPEDCHALLVAEGVSVLSQTPSAAAMLPPEGLDSVALVVAG 2849 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX---LFVL 357 EACP ELVDRW P R MINAYGPTEAT+YAA+SEPL LFVL Sbjct: 2850 EACPAELVDRWGPDRAMINAYGPTEATVYAAVSEPLTAESVESGVVPIGSPVPGNALFVL 2909 Query: 358 DKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGS 417 D LRP P GVVGELYVAG GVA GY R LTA+RFVACPFG G RMYRTGDLVRW + Sbjct: 2910 DGRLRPVPAGVVGELYVAGAGVACGYWRRAGLTAARFVACPFGGAGTRMYRTGDLVRWRA 2969 Query: 418 DGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGT 477 DGQL+YLGRADEQVKIRGYRIELGE++AALA LDGV+QAVV+AREDRPGDKRLV YITGT Sbjct: 2970 DGQLDYLGRADEQVKIRGYRIELGEVRAALAWLDGVEQAVVVAREDRPGDKRLVAYITGT 3029 Query: 478 ADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTP 537 ADPA R ALAE LPAYM+PTAVV LD +PLT NGKLD RALPAPEY S A+ YRAP Sbjct: 3030 ADPAGARAALAERLPAYMIPTAVVTLDALPLTPNGKLDTRALPAPEY-SDADQYRAPDNA 3088 Query: 538 AEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXX 597 E+ILA +YAQVLG++RVGVDDSFFDLGGDSI SMQVV RARAAG+ CR RDIFVEQT Sbjct: 3089 VEEILAGIYAQVLGLDRVGVDDSFFDLGGDSISSMQVVTRARAAGLICRTRDIFVEQTVA 3148 Query: 598 XXXXXXXXXXES-HVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVV 656 + V DEGVGPV ATPIMRWLR+V GP QFNQ ++ QAPAG E D + Sbjct: 3149 RLARVAEVADAAADVADEGVGPVAATPIMRWLRDVAGPVDQFNQAMLVQAPAGAGEADAL 3208 Query: 657 VILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNR 716 +LQALLDRH LRLRV+D D WSL VPEAG+V AR+CL TV LTD + EAR+R Sbjct: 3209 AVLQALLDRHGMLRLRVDDAGGD---WSLTVPEAGSVDARDCLHTVGELTDAAVAEARSR 3265 Query: 717 LDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGG 776 L+PAAGAM+SA+W T QLV++IHHLAVDGVSWRILLEDLNIAWAQH GQ + LPA G Sbjct: 3266 LNPAAGAMLSALWAGSTGQLVVIIHHLAVDGVSWRILLEDLNIAWAQHRAGQPVALPAAG 3325 Query: 777 TSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVET 836 TSFARW++ LAE A V D DAW+ V + P ALP V+P+TDT+ TAG LSA LD ET Sbjct: 3326 TSFARWASRLAERASHPDVVDQLDAWQRVAATPAALPAVRPETDTFATAGHLSAELDPET 3385 Query: 837 TRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSR 896 T LLG VPAAF AGVQDILL+AF LA EFL PIG+DVE HGR +EL D+DLSR Sbjct: 3386 TGMLLGAVPAAFHAGVQDILLIAFALAVAEFLGTGGAPIGIDVESHGRDEELGRDLDLSR 3445 Query: 897 TVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEV 956 TVGWFT KYP +LT L W QVV+GD +LG +K KEQLR+LP+ L YGLLR+L Sbjct: 3446 TVGWFTAKYPASLTPAELRWAQVVSGDTSLGAALKDAKEQLRALPDPLGYGLLRHLAHAT 3505 Query: 957 DLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTI 1016 L +DP IGFNYLGR G G+ EL++E+WR Q +PMPLMHT+ELNA T+ Sbjct: 3506 GLDAADPPIGFNYLGRQG-GSAELTDEMWRPVQDAVTAAAAA--IPMPLMHTLELNAATV 3562 Query: 1017 DTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLT 1076 DT +GP L A+WTWAPSA DE+ RLSRLWFEALAGICAHVR GGGGLTPSD+APARL+ Sbjct: 3563 DTADGPRLHANWTWAPSALDEDLVRRLSRLWFEALAGICAHVRSGGGGLTPSDIAPARLS 3622 Query: 1077 QRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDD---VYAVQLDITITGVLDQHR 1133 Q+QID L +++ + DVLPLTPVQQGLLFH+ RG +D +YA QLDI +TG LD R Sbjct: 3623 QQQIDRLQRQHRIADVLPLTPVQQGLLFHAHTVRGGREDATDLYAGQLDIGVTGPLDPDR 3682 Query: 1134 LRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAA 1193 LR+AVH VV RHPNL ARF +QF EPVQV+TADP AW+YL+L D D I +LCAA Sbjct: 3683 LREAVHAVVKRHPNLVARFFDQFDEPVQVITADPAPAWQYLELE-DGPGADERIRRLCAA 3741 Query: 1194 ERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPA 1253 ER+AVCDL +P FR ALIRT ++HR VLT HH+V+DGWS+PILL +IFA Y+G RLPA Sbjct: 3742 ERAAVCDLANQPPFRVALIRTGTDRHRLVLTNHHVVLDGWSMPILLGDIFAAYYGQRLPA 3801 Query: 1254 AAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGV--PGPRGIESYRVSAETTR 1311 AAPYR+FV+WL W EV GF+ P LV PG +G++S+ + AE TR Sbjct: 3802 AAPYRSFVSWLAARDRDAARAAWGEVFAGFDAPALVGRQDQLRPGEQGVQSFTLPAELTR 3861 Query: 1312 ALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINT 1371 A GELARS HTT+NTVLQAA+ QLL +TGQ DV FGT VSGRPA++ GAE+MVGLLINT Sbjct: 3862 AAGELARSCHTTVNTVLQAAYAQLLCWLTGQHDVVFGTTVSGRPAEIPGAETMVGLLINT 3921 Query: 1372 VPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPID 1431 VP+RA ++ TT +LL QLQ HN TL+H+HLALN+IH ++G ++LFDTLF YE+YPID Sbjct: 3922 VPVRATLTPTTTAAELLEQLQRAHNHTLDHQHLALNEIHRITGQDKLFDTLFAYENYPID 3981 Query: 1432 TSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQR 1491 +A G EL++T+ +RE HYPL++ A PG E+ LRVE+DT VFD + TLIDR +R Sbjct: 3982 AAALSGDHELSITDIASRESTHYPLTIQAQPGPEMRLRVEHDTDVFDADAVATLIDRLRR 4041 Query: 1492 LLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEA 1551 +L+AM DP R LS+ D +D E L+E NRAVL + P SIP +FA QV R P+A Sbjct: 4042 VLDAMTTDPGRPLSATDALDAAEHRLLEEMGNRAVLARSW-VPVSIPGLFAAQVVRTPDA 4100 Query: 1552 PAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAA 1611 AV+ G SL YGEL+E+AN+LA++L GA PG SVA+++ RS +AIVAILAVLKTGAA Sbjct: 4101 VAVSCAGGSLTYGELEESANRLAHVLIERGAGPGASVAVVLSRSTEAIVAILAVLKTGAA 4160 Query: 1612 YLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLT 1671 YLPIDP++PAAR+EFML D PVAA+TT L + G+ L V++V PA+ P+T Sbjct: 4161 YLPIDPALPAARIEFMLSDTAPVAALTTAALAEKLAGYVLPVIDVHSPALAGQPATAPAP 4220 Query: 1672 -PSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVS 1730 P P+D+A++IYTSGTTGVPKGVA++H NVT++ D + G G VW+Q+HS FD S Sbjct: 4221 GPEPEDVAHIIYTSGTTGVPKGVAVSHANVTRLFDAPEVGVVLGSGQVWTQFHSYAFDFS 4280 Query: 1731 VWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTAL 1790 VWEIWGALLHGGRLV+VPE++A SP D HALLV+E V VL QTP+AVRM+SP+GLEGTAL Sbjct: 4281 VWEIWGALLHGGRLVVVPEAVARSPKDFHALLVTERVTVLSQTPAAVRMLSPQGLEGTAL 4340 Query: 1791 VVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFV 1850 V+ E P EVVDRWA RVM+N YGPTE+TI+A S PL+ P GS VP A FV Sbjct: 4341 VIGAEPVPAEVVDRWAPGRVMVNVYGPTETTIFATASTPLAAKGGAPPTGSAVPGTALFV 4400 Query: 1851 LDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWG 1910 LD WLRP P GVVGELY+A LTG+RFVACPFG PGARMYRTGDLV WG Sbjct: 4401 LDGWLRPTPVGVVGELYVAGRGVGLGYVRRAGLTGSRFVACPFGAPGARMYRTGDLVCWG 4460 Query: 1911 DDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITG 1970 DGQL+Y+GRAD QVKIRGYRIE+GEIQ+ L+ +DGV+QAVV+ REDRPGDKRLVGY+TG Sbjct: 4461 ADGQLRYVGRADAQVKIRGYRIEIGEIQSTLAALDGVEQAVVVVREDRPGDKRLVGYLTG 4520 Query: 1971 TADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETE 2030 +A+PAA R+ L RLP YMVPAA+V L LP+TVNGKLD RALPAPEY YRAP T Sbjct: 4521 SAEPAALRAALAERLPGYMVPAAIVALPELPMTVNGKLDTRALPAPEYHGT-GYRAPSTP 4579 Query: 2031 TEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTV 2090 TE+ LAGI+A VLGV+R AMR+ AAVNT LD LSVR LFEAPT+ Sbjct: 4580 TEEILAGIYAQVLGVDRVGIDQSFFDLGGDSISAMRLIAAVNTDLDEYLSVRALFEAPTI 4639 Query: 2091 AKLSLHVEHDAGERTDRV 2108 A+L+ + GE T R+ Sbjct: 4640 AQLAPRI----GEGTGRL 4653 Score = 849 bits (2194), Expect = 0.0 Identities = 493/1057 (46%), Positives = 632/1057 (59%), Gaps = 57/1057 (5%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ Q L F F VY + + + + G +D A+ VV RH +L Sbjct: 8 VIPLSFAQNRLWFIDQFQGP--SPVYNIAVALRLRGRVDTGAFGAALADVVGRHESLRTV 65 Query: 1152 FVEQFGEPVQVLTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 F G P QV+ + + +D RG + + + A DL A Sbjct: 66 FASADGIPQQVVLPPERARLGFGTVDARG---WTEGRLREAMDAAAGHTFDLANEIPIHA 122 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVN 1262 L T ++H V HHI DGWS+ L +++ Y R P AP Y +F Sbjct: 123 ELFTTDDDEHVLVAVVHHIAADGWSIAPLARDLGVAYASRCAGREPDWAPLSVQYVDFTL 182 Query: 1263 WLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAE 1308 W W E L G + PT P V RG + E Sbjct: 183 WQRAQFGELEDSDSRIAAQLDFWEETLAGMPELLQLPTDRPYPPVADHRGARLAVDWPTE 242 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVG 1366 + + +AR + T V+QAA+ LL ++T DVA G ++GR PA + +VG Sbjct: 243 LQQQIRRVAREHNATSFMVIQAAFAALLAKITASDDVAVGFPIAGRRDPA----LDELVG 298 Query: 1367 LLINTVPIRA---KVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHE 1416 +NT+ +R ++ D T +LL Q++ EH+ + LN ++ H Sbjct: 299 FFVNTLVLRVDLKELGGDPTFAELLAQVRRRSLAAFEHQDVPFEFLVDRLNPTRSLT-HH 357 Query: 1417 QLFDTLFLYESYP---IDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGH--------E 1465 L L +E++P + +A + + ++ T + +L Sbjct: 358 PLIQVLLGWENFPGYDTNPTATLALGDVQATPMPVETHTARMDLTFSLADRWTEAGRHAG 417 Query: 1466 LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRA 1525 +G+ EY T V+D + +LI+R QRLL A+ DPARRLS++D++D E +L W N Sbjct: 418 IGVTAEYRTDVYDADTVVSLIERLQRLLAAVTSDPARRLSTVDLLDAGEHARLQRWGNTG 477 Query: 1526 VLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPG 1585 VL +P +P S+P +FA Q R P+A A+ +G S+ Y ELDEAAN+LA+L+ +GA PG Sbjct: 478 VLARPA-TPVSVPALFAAQAARTPDAVALVCDGRSMTYRELDEAANRLAHLMIRHGARPG 536 Query: 1586 KSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSR 1645 + VAL+ PRSA AIVAI+A LK+GAAYLPIDP++PAAR+EFML DA P+AAVTT L R Sbjct: 537 ERVALLFPRSAQAIVAIVAALKSGAAYLPIDPALPAARMEFMLTDAAPIAAVTTAALAGR 596 Query: 1646 FDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLD 1705 DGFDL V++ DDPAV+ P T P PDD+A++IYTSGTTGVPKGVA+T NV Q+ D Sbjct: 597 LDGFDLAVIDADDPAVDDQPGTAPPGPGPDDLAHVIYTSGTTGVPKGVAVTQHNVAQLFD 656 Query: 1706 TLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSE 1765 +L + P VW+Q+HS FD SVWEIWGALLHGGRLV+VPES++ SP++ HALLV E Sbjct: 657 SLRIGIELTPEQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPESVSRSPEEFHALLVRE 716 Query: 1766 GVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAA 1825 G VL QTPSAV ++ +GL+ TALV+ E CP E+VDRWA RVM+N YGPTE+T++A Sbjct: 717 GATVLTQTPSAVGLLPTDGLDATALVIGAEPCPPELVDRWAPGRVMVNVYGPTETTMWAC 776 Query: 1826 ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTG 1885 SAPL GS PIGSPV + A FVLDEWLRPVP GVVGELYLA LT Sbjct: 777 KSAPLDAGSGFPPIGSPVTRAAFFVLDEWLRPVPAGVVGELYLAGDGVGVGYWRRSALTA 836 Query: 1886 TRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVD 1945 +RF+ACPFG PG RMYRTGDLV WG DGQL+YLGRADEQVKIRGYRIELGEIQAALS VD Sbjct: 837 SRFMACPFGAPGTRMYRTGDLVCWGTDGQLRYLGRADEQVKIRGYRIELGEIQAALSAVD 896 Query: 1946 GVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVN 2005 GV+QAVV+AREDRPGDKRLVGY+TGTAD AAR+ + RLPAYMVPAAVV L LP+TVN Sbjct: 897 GVEQAVVVAREDRPGDKRLVGYVTGTADAGAARAAVAERLPAYMVPAAVVVLPALPMTVN 956 Query: 2006 GKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAM 2065 GKLD RALPAP+Y+ YRAP T TE+ LAGIFA VLGVER M Sbjct: 957 GKLDTRALPAPDYRDTANYRAPATATEEILAGIFADVLGVERVGADDSFFDLGGDSLSTM 1016 Query: 2066 RVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 R+ +AVN ALD DL VR +FEAPTVA+L+ ++ AG Sbjct: 1017 RLISAVNAALDTDLPVRVVFEAPTVAQLAPRIDEGAG 1053 Score = 839 bits (2167), Expect = 0.0 Identities = 507/1050 (48%), Positives = 634/1050 (60%), Gaps = 63/1050 (6%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ Q L F VY + + + G LD L A+ VVARH +L Sbjct: 4664 VVPLSFAQSRLWFLDQLQGP--SPVYNMAAAMRLRGRLDAQALGAALADVVARHESLRTV 4721 Query: 1152 FVEQFGEPVQVLTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 F G P QV+ WR +D G P ++ A DL RA Sbjct: 4722 FAAPDGTPQQVVVPAEQADFGWRVIDAGG---WPASRLDDAVKAAARDTFDLSTDIPLRA 4778 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP--------YRNFV 1261 L R + ++H V HHI DGWSL L ++ Y R +P Y ++ Sbjct: 4779 WLFRVADDEHVLVAVVHHIAADGWSLRPLAADLGVAY-ASRCAGQSPEWAELPVQYVDYT 4837 Query: 1262 NWLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSA 1307 W W + L G + PT P V RG A Sbjct: 4838 LWQRDQFGDLKDSDSRIAAQLAYWEDALAGMPERLQLPTDRPYPQVADQRGASVPIDWPA 4897 Query: 1308 ETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMV 1365 + + + +AR + T V+QAA LL ++ DVA G ++GR PA + +V Sbjct: 4898 DLQQQVAAVAREHNATSFMVVQAALAVLLSKVGATSDVAVGFPIAGRRDPA----LDDLV 4953 Query: 1366 GLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQL 1418 G +NT+ +R V+ D T +LL ++++ + EH+ + +N ++ H L Sbjct: 4954 GFFVNTLVLRVDVAGDPTFAELLDRVRTRSLEAFEHQDVPFEVLVERVNPTRSLT-HHPL 5012 Query: 1419 FDTLFLYESYP-IDTSAFMG-------VQELAVTEFNNREYNHYPLSVMALPGHE---LG 1467 + ++++ D A G V + + R + L+ G+E +G Sbjct: 5013 IQVMLAWQNFGGQDNDAATGLALGDVRVSSIPLDTQVARMDLTFSLAERWTEGNEPGGIG 5072 Query: 1468 LRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 RVE+ T VFD IETL++R QR+L AM DPAR +SS+D++D ER +L+E +RA L Sbjct: 5073 GRVEFRTDVFDAESIETLVERLQRVLAAMTTDPARTVSSVDLLDAAERARLEELGHRAAL 5132 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 T P P SIP FA QV R P+APA+ + Y ELDEAAN+LA+LLA GA PG + Sbjct: 5133 TAPAAEPLSIPAAFAAQVARTPDAPALGCGARTWTYRELDEAANRLAHLLAGRGAGPGHT 5192 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VAL+ RSA+AIVAILA LKTGAAYLP+DP+ PAAR+ FML DA PVAA+TT DL R D Sbjct: 5193 VALLFNRSAEAIVAILAALKTGAAYLPVDPAHPAARIGFMLADAAPVAALTTADLADRLD 5252 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 D+ V++VDDPAVE P+T L PS +D+AY+IYTSGTTGVPKGVA++H +VT ++ ++ Sbjct: 5253 EHDVAVIDVDDPAVETQPATALPAPSAEDVAYLIYTSGTTGVPKGVAVSHRSVTGLMASV 5312 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 A LP VWSQWHS FDVSVWEI+GALL GGRLV+VP+++ SP+DLHALLV EGV Sbjct: 5313 DARLP--DAGVWSQWHSYGFDVSVWEIFGALLRGGRLVVVPDAVVRSPEDLHALLVGEGV 5370 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVD-RVMINAYGPTESTIYAAI 1826 +VL QTPSA M+ P GLE ALVVAGEACPT++VDRWA RVMINAYGPTE+T+YAAI Sbjct: 5371 SVLSQTPSAAAMLDPAGLESAALVVAGEACPTDLVDRWATSGRVMINAYGPTEATVYAAI 5430 Query: 1827 SAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGT 1886 SAPL+PGS VVPIGSPV A FVLDE+LRPVPPGVVGELY+A LT + Sbjct: 5431 SAPLTPGSGVVPIGSPVAGAALFVLDEYLRPVPPGVVGELYVAGGGLARGYWRRAALTAS 5490 Query: 1887 RFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDG 1946 RFVACPFG PG RMYRTGDLV WG DGQLQYLGRADEQVKIRGYRIELGEIQAAL+++ G Sbjct: 5491 RFVACPFGGPGDRMYRTGDLVCWGADGQLQYLGRADEQVKIRGYRIELGEIQAALAELRG 5550 Query: 1947 VDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNG 2006 V QA V+AREDRPGDKRLVGYITG ADPA R+ L +RLPAYMVP AVVTL+ LPLT NG Sbjct: 5551 VRQAAVVAREDRPGDKRLVGYITGKADPAELRARLADRLPAYMVPVAVVTLDALPLTPNG 5610 Query: 2007 KLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMR 2066 KLD RALPAPEY A RYRAP T E+ LAGI+A VLGVER +M+ Sbjct: 5611 KLDARALPAPEYSDADRYRAPGTPVEEILAGIYAQVLGVERIGVDDSFFDLGGDSISSMQ 5670 Query: 2067 VTAAVNTALDADLSVRT--LFEAPTVAKLS 2094 V V A A L+ RT +F TVA+L+ Sbjct: 5671 V---VTRARAAGLTCRTRDIFVEQTVARLA 5697 Score = 799 bits (2063), Expect = 0.0 Identities = 505/1101 (45%), Positives = 635/1101 (57%), Gaps = 85/1101 (7%) Query: 1045 RLWFEA--LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGL 1102 R+ FEA +A + + GGGGL P A D V+PL+ Q L Sbjct: 2085 RVVFEAPTVAQLALRIGEGGGGLEPLVAA----------------DRPAVVPLSFAQNRL 2128 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 F VY + + + G LD L A+ VVARH +L G P Q+ Sbjct: 2129 WFLDQLQGP--SPVYNMAAALRLRGRLDADALGAALADVVARHESLRTLIAAPEGTPQQL 2186 Query: 1163 LTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHR 1220 +T W +D ++++ DL RA L R ++H Sbjct: 2187 VTPVEQADFGWEIVDATAWSAG---QLDEAIGDAARYTFDLAAEIPLRAELFRVDEDEHV 2243 Query: 1221 FVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNWLXXXXXXXXX 1273 V HHI DG S+ L++++ Y + P AP Y ++ W Sbjct: 2244 LVAVVHHIAADGMSITPLVRDLGMAYASRCAGQAPGWAPLEVQYVDYTLWQRAQFGDLDD 2303 Query: 1274 XX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTRALGELARS 1319 W E L G + P P V RG AE + +G LAR Sbjct: 2304 RESPIAAQLAYWEEALAGMPDRVQLPADRPYPLVADQRGATVEIAWPAELQQRVGALARK 2363 Query: 1320 QHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAK 1377 + T V+Q+A LL +++ DVA G ++GR PA + +VG +NT+ +R Sbjct: 2364 HNATSFMVVQSALAVLLSKISASSDVAVGFPIAGRRDPA----LDELVGFFVNTLVLRVD 2419 Query: 1378 VSADTTVGDLL-----RQLQSHHNDTLEHEHLA--LNDIHHVSGHEQLFDTLFLYESY-- 1428 V+ D T DLL R L ++ N + E L LN ++ H L + ++++ Sbjct: 2420 VTGDPTFTDLLAQVRQRSLAAYENQDVPFEVLVERLNPARSLT-HHPLVQVMLAWQNFAG 2478 Query: 1429 ----PIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHE------LGLRVEYDTSVFD 1478 P+ +G E+A + + +A E +G VE+ T VFD Sbjct: 2479 QDAGPV-AGLSLGDVEIAPIPVDTQTARMDLTFSLAERWSEAGEPAGIGGTVEFRTDVFD 2537 Query: 1479 VSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIP 1538 I L+ R QR+L AM DPAR LSS+D++D+ E LD NRAVLT P +P SIP Sbjct: 2538 ADSIAALVARLQRVLTAMTVDPARPLSSLDLLDEAEHAHLDRIGNRAVLTAPAAAPVSIP 2597 Query: 1539 EVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADA 1598 +FA QV R PEA A+ G S+ Y ELDEAAN+LA +LA GA PG+SVAL+ RSA+A Sbjct: 2598 ALFAAQVARTPEAVALACAGRSMTYRELDEAANRLAGVLAGRGAGPGESVALLFSRSAEA 2657 Query: 1599 IVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDD 1658 IVAILAVLK+GAAYLPIDP++P +R+ F+L DA P+A VTT DL R G D+ V++V D Sbjct: 2658 IVAILAVLKSGAAYLPIDPALPESRIGFVLSDAAPLAVVTTADLADRLIGHDVPVIDVGD 2717 Query: 1659 PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAV 1718 ++ + L P P+DIAY+IYTSGTTGVPKGVA+TH N TQ+L + A LP V Sbjct: 2718 --IDTARAAALTAPGPEDIAYLIYTSGTTGVPKGVAVTHRNATQLLARMDAGLPR--AGV 2773 Query: 1719 WSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVR 1778 WSQWHSL FDVSV EI+GALLHGGRLV+VPE++A SP+D HALLV+EGV+VL QTPSA Sbjct: 2774 WSQWHSLAFDVSVHEIFGALLHGGRLVVVPETVARSPEDCHALLVAEGVSVLSQTPSAAA 2833 Query: 1779 MMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPL---SPGSD 1835 M+ PEGL+ ALVVAGEACP E+VDRW DR MINAYGPTE+T+YAA+S PL S S Sbjct: 2834 MLPPEGLDSVALVVAGEACPAELVDRWGPDRAMINAYGPTEATVYAAVSEPLTAESVESG 2893 Query: 1836 VVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGE 1895 VVPIGSPVP A FVLD LRPVP GVVGELY+A LT RFVACPFG Sbjct: 2894 VVPIGSPVPGNALFVLDGRLRPVPAGVVGELYVAGAGVACGYWRRAGLTAARFVACPFGG 2953 Query: 1896 PGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAR 1955 G RMYRTGDLVRW DGQL YLGRADEQVKIRGYRIELGE++AAL+ +DGV+QAVV+AR Sbjct: 2954 AGTRMYRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGEVRAALAWLDGVEQAVVVAR 3013 Query: 1956 EDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPA 2015 EDRPGDKRLV YITGTADPA AR+ L RLPAYM+P AVVTL+ LPLT NGKLD RALPA Sbjct: 3014 EDRPGDKRLVAYITGTADPAGARAALAERLPAYMIPTAVVTLDALPLTPNGKLDTRALPA 3073 Query: 2016 PEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTAL 2075 PEY A +YRAP+ E+ LAGI+A VLG++R +M+V V A Sbjct: 3074 PEYSDADQYRAPDNAVEEILAGIYAQVLGLDRVGVDDSFFDLGGDSISSMQV---VTRAR 3130 Query: 2076 DADLSVRT--LFEAPTVAKLS 2094 A L RT +F TVA+L+ Sbjct: 3131 AAGLICRTRDIFVEQTVARLA 3151 Score = 779 bits (2012), Expect = 0.0 Identities = 475/1052 (45%), Positives = 621/1052 (59%), Gaps = 53/1052 (5%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ Q L F VY + + + G LD LR A+ VV RH +L Sbjct: 1066 VIPLSFAQNRLWFIQQLQGP--SPVYNMAAALRLGGPLDADALRAALADVVGRHESLRTL 1123 Query: 1152 FVEQFGEPVQVLTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 F + G P QV+ A W +D G P E++ + A + DL RA Sbjct: 1124 FPAREGTPEQVVLAAERADFGWDVVDATG---LPAGELDGVIAETTAHTFDLASEIPLRA 1180 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVN 1262 L +H V+ HHI DG SL L ++ Y R P A Y ++ Sbjct: 1181 KLFALDEREHLLVIVVHHIAADGLSLTPLAADLSVAYAARSAGRAPGWADLPVQYVDYTL 1240 Query: 1263 WLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIESYRVS--A 1307 W W E L G E PT P V RG S V A Sbjct: 1241 WQRAQFGDLDDSESPIAAQLAYWEEALAGMPERLELPTDRPYPPVADQRG-SSVVVDWPA 1299 Query: 1308 ETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGL 1367 E + + +AR + T V+QAA LL ++ DV+ G ++GR D A + +VG Sbjct: 1300 ELQQQVRRVAREHNATTFMVVQAALAVLLSKVIASTDVSVGFPIAGR-RDRA-LDQLVGF 1357 Query: 1368 LINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFD 1420 +NT+ +R + + ++ +LL ++Q+ + EH+ + LN + ++ H L Sbjct: 1358 FVNTLVLRVDLGGNPSLAELLGRVQARSLEAFEHQDVPFELLVERLNPVRSLT-HHPLVQ 1416 Query: 1421 TLFLYESYP--IDTSAFMGVQELAVTEFNNREYNHYPLSVMALP------GHELGL--RV 1470 + ++++ D +A + + +L V+ + V +L G G+ RV Sbjct: 1417 VMLAWQNFAGHDDPAAGLALGDLEVSSVPVDTQSARMDLVFSLAERWTETGEAAGIGGRV 1476 Query: 1471 EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQP 1530 E+ T VFD +E LI R +R+L A+ DP + LSS+D++DD ER +L+ + N+AVLT P Sbjct: 1477 EFRTDVFDADTVEALIGRLRRVLAALTADPGQALSSVDLLDDGERARLEGFGNQAVLTDP 1536 Query: 1531 VDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVAL 1590 + S+P +FA +V P A A+T G S+ Y ELD A+N+LA+ L G PG++VAL Sbjct: 1537 PSTSVSVPSLFAARVAEAPGAVALTCGGLSVTYRELDVASNRLAHHLVSRGVGPGQTVAL 1596 Query: 1591 MVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFD 1650 + RSA+A+ A++AVLKTGAAYLPIDPS P AR+ F+LGDA+PV A++T L R DG Sbjct: 1597 LFSRSAEAVAAMMAVLKTGAAYLPIDPSSPDARIGFVLGDAEPVVALSTAALAGRLDGHA 1656 Query: 1651 LQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAE 1710 + V++VDD ++ P L P + +AY+IYTSGTTGVPKGV +TH NVT +L L A Sbjct: 1657 VVVIDVDDAGIDAEPDIGLPEPDAEGLAYVIYTSGTTGVPKGVGVTHRNVTALLGALGAG 1716 Query: 1711 LPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVL 1770 LP PG VWS HSL FDVSVWEI+ LL GGRLVIV E A +P++L A+L+ E V+VL Sbjct: 1717 LPV-PG-VWSHAHSLAFDVSVWEIFAPLLRGGRLVIVDEDTARAPEELRAVLIGERVSVL 1774 Query: 1771 YQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPL 1830 QTPSA+ M+ P GL+ A+V+AGEACP EVVDRWA RV++NAYGPTE+T+ AISAPL Sbjct: 1775 TQTPSAIAMLDPGGLDEVAVVLAGEACPAEVVDRWAPGRVLVNAYGPTETTMCVAISAPL 1834 Query: 1831 SPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVA 1890 PGS V PIGSPVP VLD WLRPVPPGVVGELY+A LTG+RFVA Sbjct: 1835 GPGSGVPPIGSPVPGAGLLVLDGWLRPVPPGVVGELYVAGAGVAAGYLGRAGLTGSRFVA 1894 Query: 1891 CPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQA 1950 CPFG G RMYRTGDL WG DGQL+YLGRADEQVKIRGYRIELGEIQAALS + GV+QA Sbjct: 1895 CPFGAAGLRMYRTGDLACWGADGQLRYLGRADEQVKIRGYRIELGEIQAALSALAGVEQA 1954 Query: 1951 VVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDR 2010 VVIAREDRPGDKRLVGY+TG AD R++L+ RLP +MVP A+V L+ +PLT NGKLD Sbjct: 1955 VVIAREDRPGDKRLVGYVTGGADVEVLRAQLSARLPGFMVPTAIVGLDRVPLTANGKLDI 2014 Query: 2011 RALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAA 2070 RALPAP+Y S Y AP+T TE+ LA IFA VLG++R AM + AA Sbjct: 2015 RALPAPDYSSGD-YHAPQTPTEEILAAIFADVLGLDRVSTDDSFFELGGESISAMGLIAA 2073 Query: 2071 VNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 VNT L+A L VR +FEAPTVA+L+L + G Sbjct: 2074 VNTNLNAGLQVRVVFEAPTVAQLALRIGEGGG 2105 Score = 774 bits (1999), Expect = 0.0 Identities = 450/937 (48%), Positives = 581/937 (62%), Gaps = 62/937 (6%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +T++P+ R L + DLLD EH +++ WGN VL P TPV++PALFA Q R PDAVAL Sbjct: 448 VTSDPARR-LSTVDLLDAGEHARLQRWGNTGVLARPA-TPVSVPALFAAQAARTPDAVAL 505 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V RS TYRELDEA+NRLAH++ HGA+PG VA L PRS +AI++I++ LK+GAAYLP Sbjct: 506 VCDGRSMTYRELDEAANRLAHLMIRHGARPGERVALLFPRSAQAIVAIVAALKSGAAYLP 565 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P AR+ FM++DA P+AA+TTA L RLD +DLAVID DPA+D +P A GP P Sbjct: 566 IDPALPAARMEFMLTDAAPIAAVTTAALAGRLDGFDLAVIDADDPAVDDQPGTAPPGPGP 625 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DDLA++ YTSGTTGVPK VAVT HNV QL +L + P QVW+Q+HS FD SVWEI Sbjct: 626 DDLAHVIYTSGTTGVPKGVAVTQHNVAQLFDSLRIGIELTPEQVWTQFHSYAFDFSVWEI 685 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPESV SP++ H LL+ E +VL QTPSA G+L +GL++T L++ Sbjct: 686 WGALLHGGRLVVVPESVSRSPEEFHALLVREGATVLTQTPSAVGLLPTDGLDATALVIGA 745 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 E CP ELVDRWAPGRVM+N YGPTE T++A S PL FVLD+W Sbjct: 746 EPCPPELVDRWAPGRVMVNVYGPTETTMWACKSAPLDAGSGFPPIGSPVTRAAFFVLDEW 805 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELY+AG GV GY R LTASRF+ACPFG G RMYRTGDLV WG+DGQ Sbjct: 806 LRPVPAGVVGELYLAGDGVGVGYWRRSALTASRFMACPFGAPGTRMYRTGDLVCWGTDGQ 865 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L YLGRADEQVKIRGYRIELGEIQAAL+ +DGV+QAVV+AREDRPGDKRLVGY+TGTAD Sbjct: 866 LRYLGRADEQVKIRGYRIELGEIQAALSAVDGVEQAVVVAREDRPGDKRLVGYVTGTADA 925 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 R A+AE LPAYMVP AVVVL +P+TVNGKLD RALPAP+YR AN YRAP+T E+ Sbjct: 926 GAARAAVAERLPAYMVPAAVVVLPALPMTVNGKLDTRALPAPDYRDTAN-YRAPATATEE 984 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRP-RDIFVEQTXXXX 599 ILA ++A VLGVERVG DDSFFDLGGDS+ +M++++ AA P R +F T Sbjct: 985 ILAGIFADVLGVERVGADDSFFDLGGDSLSTMRLISAVNAALDTDLPVRVVFEAPTVAQL 1044 Query: 600 XXXXXXXXESHVVDEGVG---PVVA------TPI------MRWLREVDGPTGQFNQTVIT 644 +DEG G P+VA P+ + +++++ GP+ +N Sbjct: 1045 APR---------IDEGAGRLAPLVAGERPAVIPLSFAQNRLWFIQQLQGPSPVYNMAAAL 1095 Query: 645 QAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA 704 + + D + L ++ RH +LR + +E T E +L E G VDA Sbjct: 1096 RLGGPLDADALRAALADVVGRHESLR-TLFPAREGTPEQVVLAAERADFG----WDVVDA 1150 Query: 705 L------TDDVLVEARNRLDPAAG-----AMVSAVWVRETSQLVLMIHHLAVDGVSWRIL 753 D V+ E A A + A+ RE LV+++HH+A DG+S L Sbjct: 1151 TGLPAGELDGVIAETTAHTFDLASEIPLRAKLFALDERE-HLLVIVVHHIAADGLSLTPL 1209 Query: 754 LEDLNIAWAQHCTGQS---IELPAGGTSFARWSALL---AEHAKTDTVRDLADAWRAVTS 807 DL++A+A G++ +LP + W + +++ LA A+ Sbjct: 1210 AADLSVAYAARSAGRAPGWADLPVQYVDYTLWQRAQFGDLDDSESPIAAQLAYWEEALAG 1269 Query: 808 VPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFR---AGVQDILLVAFGLAW 864 +P+ L + D A Q +S+ V+ +L +V R A ++ A + Sbjct: 1270 MPERL-ELPTDRPYPPVADQRGSSVVVDWPAELQQQVRRVAREHNATTFMVVQAALAVLL 1328 Query: 865 TEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 ++ + +D +G + G D L + VG+F Sbjct: 1329 SKVIASTDVSVGFPIAGR-------RDRALDQLVGFF 1358 Score = 749 bits (1934), Expect = 0.0 Identities = 459/970 (47%), Positives = 570/970 (58%), Gaps = 71/970 (7%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L + D LD EH +E GNRAVL PV+IP LFA QVVR PDAVA+ Sbjct: 4046 MTTDPG-RPLSATDALDAAEHRLLEEMGNRAVLARSW-VPVSIPGLFAAQVVRTPDAVAV 4103 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 S TY EL+E++NRLAHVL E GA PGA+VA ++ RS EAI++IL+VLKTGAAYLP Sbjct: 4104 SCAGGSLTYGELEESANRLAHVLIERGAGPGASVAVVLSRSTEAIVAILAVLKTGAAYLP 4163 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALS-GPR 179 +DPA P ARI FM+SD PVAALTTA L +L Y L VID+ PA+ +P+ A + GP Sbjct: 4164 IDPALPAARIEFMLSDTAPVAALTTAALAEKLAGYVLPVIDVHSPALAGQPATAPAPGPE 4223 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWE 239 P+D+A++ YTSGTTGVPK VAV+H NVT+L A + G GQVW+Q+HS FD SVWE Sbjct: 4224 PEDVAHIIYTSGTTGVPKGVAVSHANVTRLFDAPEVGVVLGSGQVWTQFHSYAFDFSVWE 4283 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVA 299 IWGALLHGGRLVVVPE+V SP D H LL+TE+V+VL QTP+A MLSP+GLE T L++ Sbjct: 4284 IWGALLHGGRLVVVPEAVARSPKDFHALLVTERVTVLSQTPAAVRMLSPQGLEGTALVIG 4343 Query: 300 GEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 E P E+VDRWAPGRVM+N YGPTE TI+A S PL LFVLD Sbjct: 4344 AEPVPAEVVDRWAPGRVMVNVYGPTETTIFATASTPLAAKGGAPPTGSAVPGTALFVLDG 4403 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WLRP P GVVGELYVAG GV GY+ R LT SRFVACPFG G RMYRTGDLV WG+DG Sbjct: 4404 WLRPTPVGVVGELYVAGRGVGLGYVRRAGLTGSRFVACPFGAPGARMYRTGDLVCWGADG 4463 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL Y+GRAD QVKIRGYRIE+GEIQ+ LA LDGV+QAVV+ REDRPGDKRLVGY+TG+A+ Sbjct: 4464 QLRYVGRADAQVKIRGYRIEIGEIQSTLAALDGVEQAVVVVREDRPGDKRLVGYLTGSAE 4523 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA LR ALAE LP YMVP A+V L +P+TVNGKLD RALPAPEY YRAPSTP E Sbjct: 4524 PAALRAALAERLPGYMVPAAIVALPELPMTVNGKLDTRALPAPEYHGTG--YRAPSTPTE 4581 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGIQCRPRDIFVEQTXXX 598 +ILA +YAQVLGV+RVG+D SFFDLGGDSI +M+++A R +F T Sbjct: 4582 EILAGIYAQVLGVDRVGIDQSFFDLGGDSISAMRLIAAVNTDLDEYLSVRALFEAPTIAQ 4641 Query: 599 XXXXXXXXXESHVVDEGVG---PVVATPI------------MRWLREVDGPTGQFNQTVI 643 + EG G P+VA P + +L ++ GP+ +N Sbjct: 4642 LAPR---------IGEGTGRLEPLVAGPRPAVVPLSFAQSRLWFLDQLQGPSPVYNMAAA 4692 Query: 644 TQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVD 703 + + + L ++ RH +LR V + T + ++ E G R +D Sbjct: 4693 MRLRGRLDAQALGAALADVVARHESLRT-VFAAPDGTPQQVVVPAEQADFG----WRVID 4747 Query: 704 A-------LTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRIL 753 A L D V AR+ D + + A R LV ++HH+A DG S R L Sbjct: 4748 AGGWPASRLDDAVKAAARDTFDLSTDIPLRAWLFRVADDEHVLVAVVHHIAADGWSLRPL 4807 Query: 754 LEDLNIAWAQHCTGQS---IELPAGGTSFARWSALLAEHAKTDTVRDLADA--WR-AVTS 807 DL +A+A C GQS ELP + W K R A W A+ Sbjct: 4808 AADLGVAYASRCAGQSPEWAELPVQYVDYTLWQRDQFGDLKDSDSRIAAQLAYWEDALAG 4867 Query: 808 VPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFR---AGVQDILLVAFGLAW 864 +P+ L + D A Q AS+ ++ L +V A R A ++ A + Sbjct: 4868 MPERL-QLPTDRPYPQVADQRGASVPIDWPADLQQQVAAVAREHNATSFMVVQAALAVLL 4926 Query: 865 TEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDA 924 ++ SD +G + G D L VG+F V L VAGD Sbjct: 4927 SKVGATSDVAVGFPIAGR-------RDPALDDLVGFF---------VNTLVLRVDVAGDP 4970 Query: 925 ALGGIVKAVK 934 ++ V+ Sbjct: 4971 TFAELLDRVR 4980 Score = 713 bits (1840), Expect = 0.0 Identities = 435/956 (45%), Positives = 559/956 (58%), Gaps = 74/956 (7%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+P + L S DLLD+ E ++E +GN+AVLTDP T V++P+LFA +V AP AVAL Sbjct: 1502 LTADPG-QALSSVDLLDDGERARLEGFGNQAVLTDPPSTSVSVPSLFAARVAEAPGAVAL 1560 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G S TYRELD ASNRLAH L G PG TVA L RS EA+ ++++VLKTGAAYLP Sbjct: 1561 TCGGLSVTYRELDVASNRLAHHLVSRGVGPGQTVALLFSRSAEAVAAMMAVLKTGAAYLP 1620 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP+ PDARIGF++ DA+PV AL+TA L RLD + + VID+ D ID P L P Sbjct: 1621 IDPSSPDARIGFVLGDAEPVVALSTAALAGRLDGHAVVVIDVDDAGIDAEPDIGLPEPDA 1680 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 + LAY+ YTSGTTGVPK V VTH NVT L+ AL A LP PG VWS HSL FDVSVWEI Sbjct: 1681 EGLAYVIYTSGTTGVPKGVGVTHRNVTALLGALGAGLPV-PG-VWSHAHSLAFDVSVWEI 1738 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 + LL GGRLV+V E +P++L +LI E+VSVL QTPSA ML P GL+ +++AG Sbjct: 1739 FAPLLRGGRLVIVDEDTARAPEELRAVLIGERVSVLTQTPSAIAMLDPGGLDEVAVVLAG 1798 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP E+VDRWAPGRV++NAYGPTE T+ A+S PL L VLD W Sbjct: 1799 EACPAEVVDRWAPGRVLVNAYGPTETTMCVAISAPLGPGSGVPPIGSPVPGAGLLVLDGW 1858 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELYVAG GVA GY+GR LT SRFVACPFG G RMYRTGDL WG+DGQ Sbjct: 1859 LRPVPPGVVGELYVAGAGVAAGYLGRAGLTGSRFVACPFGAAGLRMYRTGDLACWGADGQ 1918 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L YLGRADEQVKIRGYRIELGEIQAAL+ L GV+QAVVIAREDRPGDKRLVGY+TG AD Sbjct: 1919 LRYLGRADEQVKIRGYRIELGEIQAALSALAGVEQAVVIAREDRPGDKRLVGYVTGGADV 1978 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 LR L+ LP +MVPTA+V LD +PLT NGKLD RALPAP+Y S DY AP TP E+ Sbjct: 1979 EVLRAQLSARLPGFMVPTAIVGLDRVPLTANGKLDIRALPAPDYSSG--DYHAPQTPTEE 2036 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA---AGIQCRPRDIFVEQTXX 597 ILA ++A VLG++RV DDSFF+LGG+SI +M ++A AG+Q R +F T Sbjct: 2037 ILAAIFADVLGLDRVSTDDSFFELGGESISAMGLIAAVNTNLNAGLQVRV--VFEAPTVA 2094 Query: 598 XXXXXXXXXXESHVVDEGVG---PVVAT------PI------MRWLREVDGPTGQFNQTV 642 + EG G P+VA P+ + +L ++ GP+ +N Sbjct: 2095 QLALR---------IGEGGGGLEPLVAADRPAVVPLSFAQNRLWFLDQLQGPSPVYNMAA 2145 Query: 643 ITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDE-----------WSLLVPEAG 691 + + D + L ++ RH +LR + + + W ++ A Sbjct: 2146 ALRLRGRLDADALGAALADVVARHESLRTLIAAPEGTPQQLVTPVEQADFGWEIVDATAW 2205 Query: 692 AVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGV 748 + G + +A+ D AR D AA + A R + LV ++HH+A DG+ Sbjct: 2206 SAGQLD-----EAIGD----AARYTFDLAAEIPLRAELFRVDEDEHVLVAVVHHIAADGM 2256 Query: 749 SWRILLEDLNIAWAQHCTGQS---IELPAGGTSFARWSALL---AEHAKTDTVRDLADAW 802 S L+ DL +A+A C GQ+ L + W + ++ LA Sbjct: 2257 SITPLVRDLGMAYASRCAGQAPGWAPLEVQYVDYTLWQRAQFGDLDDRESPIAAQLAYWE 2316 Query: 803 RAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLV---A 859 A+ +P + + D + A Q A++++ +L V A R +V A Sbjct: 2317 EALAGMPDRV-QLPADRPYPLVADQRGATVEIAWPAELQQRVGALARKHNATSFMVVQSA 2375 Query: 860 FGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLP 915 + ++ SD +G + G D L VG+F + + V P Sbjct: 2376 LAVLLSKISASSDVAVGFPIAGR-------RDPALDELVGFFVNTLVLRVDVTGDP 2424 Score = 44.3 bits (103), Expect = 0.26 Identities = 70/309 (22%), Positives = 118/309 (38%), Gaps = 36/309 (11%) Query: 627 WLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLL 686 ++ + GP+ +N V + V L ++ RH +LR V + + + +L Sbjct: 20 FIDQFQGPSPVYNIAVALRLRGRVDTGAFGAALADVVGRHESLRT-VFASADGIPQQVVL 78 Query: 687 VPEAGAVGARECLRTVDAL--TDDVLVEARNRLDPAAG---------AMVSAVWVRETSQ 735 PE +G TVDA T+ L EA +D AAG + + ++ + + Sbjct: 79 PPERARLG----FGTVDARGWTEGRLREA---MDAAAGHTFDLANEIPIHAELFTTDDDE 131 Query: 736 --LVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFARWS-ALLAEH 789 LV ++HH+A DG S L DL +A+A C G+ + L F W A E Sbjct: 132 HVLVAVVHHIAADGWSIAPLARDLGVAYASRCAGREPDWAPLSVQYVDFTLWQRAQFGEL 191 Query: 790 AKTDT-VRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAF 848 +D+ + D W + L + D A A L V+ +L ++ Sbjct: 192 EDSDSRIAAQLDFWEETLAGMPELLQLPTDRPYPPVADHRGARLAVDWPTELQQQIRRVA 251 Query: 849 R---AGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKY 905 R A ++ AF + D +G + G D L VG+F Sbjct: 252 REHNATSFMVIQAAFAALLAKITASDDVAVGFPIAGR-------RDPALDELVGFFVNTL 304 Query: 906 PVALTVENL 914 + + ++ L Sbjct: 305 VLRVDLKEL 313 >tr|A0QH53|A0QH53_MYCA1 Tax_Id=243243 SubName: Full=Linear gramicidin synthetase subunit D; EC=1.-.-.-; EC=5.1.1.-;[Mycobacterium avium] Length = 10421 Score = 2647 bits (6860), Expect = 0.0 Identities = 1358/2105 (64%), Positives = 1598/2105 (75%), Gaps = 14/2105 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P T+++ S DLLD EH ++ GNRA L+ P +IP +FAEQ R PDAVAL Sbjct: 8037 MTADP-TQSVSSVDLLDAGEHAHLDRIGNRAALSGPAAQFHSIPTVFAEQAARTPDAVAL 8095 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V DRSWTYRELDEA+NRLAH LA G G VA L RS EAI++IL+VLK GAAYLP Sbjct: 8096 VYEDRSWTYRELDEAANRLAHRLAGFGVGAGERVALLFSRSAEAIVAILAVLKAGAAYLP 8155 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA PD RIGFM++DA P+ A++TA+L RL + + V+D+ DPA+D +PS L P Sbjct: 8156 IDPALPDERIGFMLADAAPMVAISTAELAPRLHGHHVVVLDVHDPAVDTQPSTPLPPPGA 8215 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTGVPK VAV+H NVTQL++A + LP VWSQWHSL FDVSVWEI Sbjct: 8216 DDIAYLIYTSGTTGVPKGVAVSHRNVTQLLTA-DSGLPREG--VWSQWHSLAFDVSVWEI 8272 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALLHGGRLVV+P+SV SPDD H LL+ E+VSVL QTPSAAG LSPEGLEST L+VAG Sbjct: 8273 FGALLHGGRLVVIPDSVVRSPDDFHALLVDEQVSVLSQTPSAAGTLSPEGLESTALVVAG 8332 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX-LFVLDK 359 EACP ELVDRWAPGR MINAYGPTEAT+Y A+S PL LFVLD+ Sbjct: 8333 EACPAELVDRWAPGRTMINAYGPTEATVYTAISAPLQPGSPAGVPIGFPVPGTGLFVLDE 8392 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 LRP P GVVGELYVAG GVA GY R LTASRFVACPFG G RMYRTGDLVRW DG Sbjct: 8393 SLRPVPPGVVGELYVAGAGVACGYWRRGGLTASRFVACPFGRPGARMYRTGDLVRWRGDG 8452 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVK+RGYRIELGE+++ALA LDGVDQA V+AREDRPGDKRLVGYITG AD Sbjct: 8453 QLDYLGRADEQVKVRGYRIELGEVRSALAALDGVDQAAVVAREDRPGDKRLVGYITGDAD 8512 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA+ R L E LPAYMVP A+V LD IPLT NGKLD RALPAPEY S A YRAP TP E Sbjct: 8513 PAEARARLGERLPAYMVPAAIVALDAIPLTPNGKLDTRALPAPEY-SDAGQYRAPETPVE 8571 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 Q LA +YAQVLGV+RVGVDDSFFDLGGDSI SMQVV RA+AAG+ R RDIF EQT Sbjct: 8572 QTLAAIYAQVLGVQRVGVDDSFFDLGGDSISSMQVVTRAKAAGLAVRTRDIFTEQTVARL 8631 Query: 600 XXXXXXXXESH-VVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVI 658 E DEG G V ATPI+ WLR V+GP +FNQT++ QAPAGVTE DVV + Sbjct: 8632 ARVAGVADEDGGPADEGTGEVTATPIIEWLRGVNGPVDEFNQTMVLQAPAGVTEADVVAV 8691 Query: 659 LQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLD 718 LQALLDRHA LRLRV DT DT EWSL VPE G+V A + + TVD L+D ++EAR+RL+ Sbjct: 8692 LQALLDRHAMLRLRV-DTAADTGEWSLQVPEPGSVDAAQRVHTVDELSDAAIIEARSRLN 8750 Query: 719 PAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTS 778 PAAG M+SA+WV T +LVL+IHHLAVDGVSWR+LLEDLNIAW QH GQ I LPAGGTS Sbjct: 8751 PAAGVMLSALWVGSTGRLVLIIHHLAVDGVSWRVLLEDLNIAWGQHHNGQPIVLPAGGTS 8810 Query: 779 FARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTR 838 FARW++LLAEHA + V + ADAWR V + P ALPPV+P+ DTY +A L+A+LD ETTR Sbjct: 8811 FARWASLLAEHASSPAVVEQADAWRRVAATPPALPPVRPEADTYQSAENLAATLDTETTR 8870 Query: 839 QLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTV 898 LLGE PAAF AGV DILL+AF LAW EFL+ +D PIG+DVEGHGR++ELA+ VDLSRTV Sbjct: 8871 TLLGEAPAAFHAGVNDILLIAFALAWAEFLDSADAPIGIDVEGHGRHEELAAGVDLSRTV 8930 Query: 899 GWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDL 958 GWFTTKYPVALTV L WEQV +G LG +VK KEQLR+LP+ L+YGLLRY+N +VDL Sbjct: 8931 GWFTTKYPVALTVGALEWEQVTSGAPGLGALVKDAKEQLRALPDPLSYGLLRYVNTDVDL 8990 Query: 959 GGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDT 1018 G+DP IGFNYLGRLG A ELS+ELWRI + VPMPLMHTV+LNAGT+DT Sbjct: 8991 DGADPPIGFNYLGRLGGAAAELSDELWRISRDGSSATATSTAVPMPLMHTVDLNAGTMDT 9050 Query: 1019 DNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQR 1078 ++GP L A+WTWAPSA + +Q TRLSRLWF+ALAGICAHVR GGGGLTPSD+APARLT Sbjct: 9051 EHGPQLHANWTWAPSALNRDQVTRLSRLWFDALAGICAHVRAGGGGLTPSDIAPARLTPP 9110 Query: 1079 QIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAV 1138 QID+L +++ + DVLPLTP+QQGLLFH+ RG D +Y VQLD+T+TG LD+ RLR+A+ Sbjct: 9111 QIDQLERQHRIADVLPLTPLQQGLLFHANTTRGGDDHLYVVQLDLTLTGPLDRDRLREAM 9170 Query: 1139 HTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAV 1198 HTV++RHP+L ARF +QF EPVQV+ ADP +AWRYL+L + D +I +LCA ER+AV Sbjct: 9171 HTVISRHPHLGARFCDQFDEPVQVIPADPTMAWRYLELHANGSESDAQIRRLCAGERAAV 9230 Query: 1199 CDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYR 1258 DL E P RA LIRT ++HR VLT HHIV+DGWS+PILL E FA Y G RLPA APYR Sbjct: 9231 YDLAEAPAVRAVLIRTGPDRHRLVLTIHHIVLDGWSVPILLNETFACYTGQRLPAPAPYR 9290 Query: 1259 NFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG--VPGPRGIESYRVSAETTRALGEL 1316 FV WL W E L GF+TPTLV PP PG RG++++ VSAE TRALGEL Sbjct: 9291 RFVTWLAERDLDAARAAWGEALAGFDTPTLVGPPHSLEPGARGVQAFAVSAEITRALGEL 9350 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA 1376 AR+ HTT++TVLQAAW QLL+ T Q DVAFGT VSGRPA++ GA+SMVGL+INTVP+RA Sbjct: 9351 ARAHHTTVSTVLQAAWAQLLVWQTAQHDVAFGTTVSGRPAEVPGADSMVGLMINTVPVRA 9410 Query: 1377 KVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFM 1436 ++SA TT DLL +LQ H DTL+H+HLAL++IH ++G ++LFDTLF YE+YP+DTSA Sbjct: 9411 RISAATTTTDLLAELQRGHADTLDHQHLALSEIHRIAGQDKLFDTLFGYENYPLDTSALA 9470 Query: 1437 GVQELAVTEFNNREYNHYPLSVM-ALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEA 1495 EL +++ N E NHYPL++ AL G LGLRVEYD +FD + IE L R +R+L A Sbjct: 9471 VDHELTISDVNLFERNHYPLTMQAALSGDRLGLRVEYDAGIFDAATIEALSRRLERVLIA 9530 Query: 1496 MIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVT 1555 M DPAR LSS+D++D ER +LD+ NRA L P +P SIP +FA + + P+A A++ Sbjct: 9531 MTADPARPLSSVDLLDPSERQRLDDIGNRAALAGPPPAPPSIPVLFAARAAQTPDAVAIS 9590 Query: 1556 FEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPI 1615 ++G S+ Y ELD+AAN+LA+LLA +GA PG+SVAL+ RSA AIVAILAVLKTGAAYLPI Sbjct: 9591 WDGLSMTYRELDQAANRLAHLLADHGAGPGQSVALLFSRSAHAIVAILAVLKTGAAYLPI 9650 Query: 1616 DPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPD 1675 D + PAAR+ FML D+ VAAVTT LRSR DG D+ ++++DP ++ PST L P+P Sbjct: 9651 DAAAPAARVRFMLADSAAVAAVTTAGLRSRLDGCDVAAIDIEDPRIQTRPSTPLPAPAPH 9710 Query: 1676 DIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIW 1735 DIAY+IYTSGTTGVPKGVA+TH NVTQ+L+ L A LP+ PG VW+Q HS FDVSVWEI+ Sbjct: 9711 DIAYVIYTSGTTGVPKGVAVTHRNVTQLLEPLDAGLPS-PG-VWTQSHSYAFDVSVWEIF 9768 Query: 1736 GALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGE 1795 GALL GGRLV+VPE++ SP D HALLV E V VL QTPSAV M+SPEGLE +LVV GE Sbjct: 9769 GALLRGGRLVVVPEAVTRSPKDFHALLVDEEVTVLTQTPSAVAMLSPEGLESVSLVVVGE 9828 Query: 1796 ACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWL 1855 ACP EVVDRWA RVM+NAYGPTE+T+ AISAPL+PG PIG PV FVLD WL Sbjct: 9829 ACPAEVVDRWAPGRVMVNAYGPTETTMCVAISAPLAPGMGSPPIGVPVDGAGLFVLDAWL 9888 Query: 1856 RPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQL 1915 RPV PGVVGELY+A LT +RFVACPFGEPG RMYRTGDLV W DGQL Sbjct: 9889 RPVAPGVVGELYVAGAGVAAGYVGRSGLTASRFVACPFGEPGTRMYRTGDLVCWRPDGQL 9948 Query: 1916 QYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPA 1975 Y GRADEQVK+RGYRIELGE+QAAL+ +D V+QAVVIAREDRPG KRLVGYITGTADPA Sbjct: 9949 DYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAVVIAREDRPGGKRLVGYITGTADPA 10008 Query: 1976 AARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTL 2035 AR+ L RLP YMVP AVV L+ +PLT NGK+D RALP PEY + RYRAP E+T+ Sbjct: 10009 EARTALAQRLPVYMVPTAVVALDAIPLTPNGKIDTRALPTPEY-TGSRYRAPSNAVEETV 10067 Query: 2036 AGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSL 2095 AGI+AHVLGVER AMRV A+N +L +L+VRTLFEAPTVA LS Sbjct: 10068 AGIYAHVLGVERVGADDSFFELGGDSISAMRVITAINASLGVELAVRTLFEAPTVASLSR 10127 Query: 2096 HVEHD 2100 + D Sbjct: 10128 RAQTD 10132 Score = 2585 bits (6701), Expect = 0.0 Identities = 1337/2110 (63%), Positives = 1585/2110 (75%), Gaps = 23/2110 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P T+++ S DLLDE EH +++ GNRA LT P P ++P LFAEQ R PDAVAL Sbjct: 5492 MTADP-TQSVSSVDLLDEREHARLDTLGNRAALTGPPPRFDSLPTLFAEQAARTPDAVAL 5550 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V G R TYRELDEA+NR+AH+L GA PG TVA L RS EAI++IL VLK+GAAYLP Sbjct: 5551 VCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVALLFSRSAEAIVAILGVLKSGAAYLP 5610 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLD-QYDLAVIDMADPAIDRRPSDALSGPR 179 +DPA P RIGFM++DA P+ A++TA+L RL Q+D+ V+D+ DPAI+ PS AL P Sbjct: 5611 IDPALPGERIGFMLADAAPLVAISTAELAPRLHGQHDVPVVDVHDPAIEAAPSSALPPPG 5670 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWE 239 DD+AY+ YTSGTTGVPK VAV+H NV QL++A + LP VWSQWHSL FDVSVWE Sbjct: 5671 ADDIAYLIYTSGTTGVPKGVAVSHRNVAQLLTA-ESGLPREG--VWSQWHSLAFDVSVWE 5727 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVA 299 I+GA LHGGRLVV+PESV SP+DLH LLITE+VSVL QTPSAAG LSPEGLE TL+VA Sbjct: 5728 IFGAQLHGGRLVVIPESVARSPEDLHALLITEQVSVLSQTPSAAGALSPEGLEDLTLVVA 5787 Query: 300 GEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX-LFVLD 358 GEACP+ELVDRWAPGR MINAYGPTEAT+YAA+S PL +FVLD Sbjct: 5788 GEACPSELVDRWAPGRTMINAYGPTEATVYAAISAPLRPGALGGVPIGSPVPGGAVFVLD 5847 Query: 359 KWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSD 418 +WLRP P GVVGELYVAG GVA GY R LTASRFVACPFG G RMYRTGDLVRW D Sbjct: 5848 EWLRPVPPGVVGELYVAGAGVACGYWRRGGLTASRFVACPFGAPGARMYRTGDLVRWRGD 5907 Query: 419 GQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA 478 GQL+YLGR DEQVKIRGYRIELGE++AALA +DGVDQAVV+AREDRP DKRLVGYITGTA Sbjct: 5908 GQLDYLGRVDEQVKIRGYRIELGEVRAALAWVDGVDQAVVVAREDRPRDKRLVGYITGTA 5967 Query: 479 DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPA 538 DPA +R ALAE LPAYMVP AVV LD IPLT NGKLD RALPAPEY S A+ YRAP Sbjct: 5968 DPAAVRAALAERLPAYMVPAAVVTLDAIPLTPNGKLDTRALPAPEY-SDADRYRAPDNAV 6026 Query: 539 EQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXX 598 E+ILA +YAQVLGV+RVGVDDSFFDLGGDSI SMQVV RARAAG+ C+ RDIFVEQT Sbjct: 6027 EEILAGIYAQVLGVQRVGVDDSFFDLGGDSISSMQVVTRARAAGLVCKTRDIFVEQTVAR 6086 Query: 599 XXXXXXXXXESHVVDEGVGPVVATPIMRWLREVD---GPTGQFNQTVITQAPAGVTEDDV 655 DEGVG + ATPI+RWL++V+ G QFNQ ++ +APAGVTE DV Sbjct: 6087 LARVAEVADADAAADEGVGEITATPIIRWLQDVESAGGQVDQFNQAMLVRAPAGVTEADV 6146 Query: 656 VVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARN 715 V +LQALLDRHA LRLRVE + T EWSL VPE G+V A CL VD L+D ++EAR+ Sbjct: 6147 VTVLQALLDRHAMLRLRVE-RDDATGEWSLQVPEPGSVDAGACLHAVDELSDAAVIEARS 6205 Query: 716 RLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAG 775 RL+PAAG M+SAVW T QLV++IHHLAVDGVSWRILL+DLNIAWAQH GQ + LPA Sbjct: 6206 RLNPAAGVMLSAVWANATGQLVVIIHHLAVDGVSWRILLQDLNIAWAQHHGGQPVALPAA 6265 Query: 776 GTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVE 835 GTSFARW++ LA HA V D A AW+AV + P ALP V+PD DT+ +AG LS LD E Sbjct: 6266 GTSFARWASRLAGHAHHPDVADRAGAWQAVAATPPALPAVRPDVDTFASAGHLSTELDTE 6325 Query: 836 TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLS 895 TT LLGEVPAAF AGVQDILL+AF LA EF TPIG+DVEGHGR +EL D+DLS Sbjct: 6326 TTAMLLGEVPAAFHAGVQDILLIAFALACAEFCGTRGTPIGIDVEGHGRREELGRDIDLS 6385 Query: 896 RTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPE 955 TVGWFTTKYPVALTV L W QVVAG LG I+KA KEQLRSLP+ L+YGLLRYLNP Sbjct: 6386 HTVGWFTTKYPVALTVGALDWAQVVAGAPGLGDILKAAKEQLRSLPDPLSYGLLRYLNPG 6445 Query: 956 VDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGT 1015 VDL G DP IGFNYLGR G GA EL+ ++WR + +PMPLMHT+ELNA T Sbjct: 6446 VDLDGDDPPIGFNYLGRQG-GATELTADMWRPEPDGWTATRAAAAIPMPLMHTLELNAVT 6504 Query: 1016 IDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARL 1075 +D+ +GP L A+WTWAPSA D++Q RLSRLW +AL GICAHVR GGGGLTPSD+APARL Sbjct: 6505 VDSASGPRLHANWTWAPSALDDQQIARLSRLWSQALTGICAHVRAGGGGLTPSDIAPARL 6564 Query: 1076 TQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLR 1135 TQ+Q+D+L++++ + DVL LTPVQQGLLFH+ A G DD+YA QLDI I G LD RLR Sbjct: 6565 TQQQLDQLARQHRIADVLALTPVQQGLLFHANTASG-SDDLYAGQLDIAIAGPLDAARLR 6623 Query: 1136 DAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAER 1195 DAVH VV RHPNL ARF +++ + VQ++ A+P AW+ ++L G++ +I QL A ER Sbjct: 6624 DAVHAVVHRHPNLVARFCDRYDQAVQIIPAEPAPAWQVVELHGEE-----QIRQLGADER 6678 Query: 1196 SAVC-DLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAA 1254 +AVC DL E P R AL+RT+ ++HR +LT HHIV+DGWS+PILL EIFA Y+G RLPA Sbjct: 6679 AAVCADLTESPALRVALVRTATDRHRLLLTNHHIVLDGWSMPILLGEIFAAYYGQRLPAP 6738 Query: 1255 APYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAP--PGVPGPRGIESYRVSAETTRA 1312 APYR FV+WL W EV GF+TPTLV P P GP+ +E++ + A+ TRA Sbjct: 6739 APYRGFVDWLAERDLDAARAAWAEVFAGFDTPTLVGPQDPVELGPQQVETFTLPADLTRA 6798 Query: 1313 LGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTV 1372 + +LARS HTT+NTVLQAA+ +LL +TGQRDV FGT VSGRPA++ GA++MVGLLINTV Sbjct: 6799 VTDLARSCHTTVNTVLQAAFARLLCALTGQRDVVFGTTVSGRPAEVPGADTMVGLLINTV 6858 Query: 1373 PIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDT 1432 P+RA ++A T+ DLL QLQ +N TL+H+HLALN+IH ++G ++LFDTLF YE+YPID Sbjct: 6859 PVRANITATTSTVDLLHQLQGAYNHTLDHQHLALNEIHRITGQDKLFDTLFAYENYPIDA 6918 Query: 1433 SAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRL 1492 A G QELAVT+ +RE HYPL+V A PG +L L++EY T VFD +I TLI+R +R+ Sbjct: 6919 GALSGDQELAVTDITSRESTHYPLTVQAQPGSQLRLQIEYATRVFDDEDIATLIERMRRV 6978 Query: 1493 LEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAP 1552 L AM DPAR LSS+DV+D E +L +W RAVL +P + SIP +F Q +R P+AP Sbjct: 6979 LVAMTADPARPLSSIDVLDPAEHQRLHDWGARAVLDRPA-TRTSIPALFTAQAQRSPQAP 7037 Query: 1553 AVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAY 1612 AVTFEG + Y ELDEA+N+LA+LL G PG++VAL++PRSADAIVAILAVLKTGAAY Sbjct: 7038 AVTFEGRTTTYRELDEASNRLAHLLIGRGVGPGQAVALLLPRSADAIVAILAVLKTGAAY 7097 Query: 1613 LPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTP 1672 LPIDP++PAAR+EFML D P AAVTT L G DL VV++ D A+ P T L P Sbjct: 7098 LPIDPALPAARIEFMLDDTAPTAAVTTAALAGPLRGRDLTVVDIGDRALSRQPHTALPAP 7157 Query: 1673 SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVW 1732 PD +A++IYTSGTTGVPKGVA++H NVT++ D + VW+Q+HS FD SVW Sbjct: 7158 DPDHVAHIIYTSGTTGVPKGVAVSHHNVTRLFDAQAVGVELSADQVWTQFHSYAFDYSVW 7217 Query: 1733 EIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVV 1792 EIWGALLHGGRLV+V +++A SP D HALLV+E V VL QTPSAVRM+SP+GLE ALV+ Sbjct: 7218 EIWGALLHGGRLVVVSDAVARSPMDFHALLVAENVTVLSQTPSAVRMLSPQGLESAALVI 7277 Query: 1793 AGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLD 1852 E CP E++DRWA R M+N YGPTE+TI++ S PL+ GS PIGSPVP A VLD Sbjct: 7278 GAEPCPPELLDRWAPGRTMVNVYGPTEATIFSTASTPLAAGSGAPPIGSPVPGTALLVLD 7337 Query: 1853 EWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDD 1912 WLRPVP GVVGELY+A LT +RFVACPFG PGARMYRTGDLVRW D Sbjct: 7338 GWLRPVPAGVVGELYVAGRGVGYGYLRRAGLTASRFVACPFGAPGARMYRTGDLVRWRAD 7397 Query: 1913 GQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTA 1972 GQL YLGRADEQVKIRGYRIE+GEI++AL+ +DGVD+AVVIAREDRPGDKRLVGYITG A Sbjct: 7398 GQLDYLGRADEQVKIRGYRIEVGEIRSALAALDGVDEAVVIAREDRPGDKRLVGYITGDA 7457 Query: 1973 DPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETE 2032 DPA AR+ L RLPAYMVP AVV L+ LP+TVNGKLD RALPAPEY +A YR+P T E Sbjct: 7458 DPAEARARLAERLPAYMVPVAVVVLDALPMTVNGKLDLRALPAPEY-AAAGYRSPTTPAE 7516 Query: 2033 KTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAK 2092 + LAGI+AHVLGV+R AMRV AA+N+ALD + VR +FEAPTVA+ Sbjct: 7517 EILAGIYAHVLGVQRVGVDDSFFDLGGDSISAMRVIAAINSALDVGVPVRAIFEAPTVAQ 7576 Query: 2093 LSLHVEHDAG 2102 L+ + DAG Sbjct: 7577 LAPRIGEDAG 7586 Score = 2160 bits (5596), Expect = 0.0 Identities = 1161/2001 (58%), Positives = 1394/2001 (69%), Gaps = 48/2001 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLT-DPGPTPVTIPALFAEQVVRAPDAVA 59 M A+P+ R L S D+L + EH Q+E GN AVLT PGP V++P LFA QV RAP VA Sbjct: 421 MAADPA-RLLSSLDVLRDPEHAQLEALGNTAVLTRTPGPA-VSVPELFATQVARAPQDVA 478 Query: 60 LVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYL 119 LV RS TYR+LDEASNRLAH+LA GA PG +VA L RS EA+ SIL+VLKTGAAYL Sbjct: 479 LVGEGRSLTYRQLDEASNRLAHLLAGLGAGPGQSVALLFSRSAEAVASILAVLKTGAAYL 538 Query: 120 PVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPR 179 P+DPA P+ RIGFM++DAKPVAAL+TA+L RL+ + + VID+ DP I RP+ AL Sbjct: 539 PIDPAAPETRIGFMLADAKPVAALSTAELAGRLEAHGMTVIDVNDPRIQDRPATALPVAA 598 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWE 239 D +AY+ YTSGTTGVPK VAVTH NVTQL+ +L A LPS VWSQ HS FDVSVWE Sbjct: 599 ADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLDAGLPSAG--VWSQCHSYAFDVSVWE 656 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVA 299 I+GALL GGRLVVVPE+V +P++LH++L+ E+VSVL QTPSA MLSP+GLES +L+V Sbjct: 657 IFGALLRGGRLVVVPEAVTRAPEELHDVLVNEQVSVLTQTPSAVAMLSPQGLESVSLVVV 716 Query: 300 GEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 GEACP E+VDRW+ GRVM+NAYGPTE T+ A+S PL LFVLD Sbjct: 717 GEACPAEVVDRWSGGRVMVNAYGPTETTMCVAISAPLAPGMGSPPIGVPVDGAGLFVLDA 776 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WLRP P GVVGELYV G GVA GY+GR LTASRFVACPFG G RMYRTGDLV W DG Sbjct: 777 WLRPVPPGVVGELYVGGAGVAAGYVGRSGLTASRFVACPFGAPGARMYRTGDLVCWRPDG 836 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+Y GRADEQVK+RGYRIELGE+QAALA LD V+QAVVIAREDRPG KRLVGYITGTAD Sbjct: 837 QLDYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAVVIAREDRPGGKRLVGYITGTAD 896 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA+ RTALA+ LP YMVP AVV LD IPLT NGKLD RALP PEY + +YRAP +P E Sbjct: 897 PAEARTALAQRLPVYMVPAAVVALDAIPLTPNGKLDTRALPTPEY--STGEYRAPESPTE 954 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 +ILA +YA+VLGV+RVGVD+SFF+LGGDSILS+QVVARARAAG+ CRPRD+FVEQT Sbjct: 955 EILAGIYAEVLGVDRVGVDESFFELGGDSILSLQVVARARAAGLTCRPRDVFVEQTVARL 1014 Query: 600 XXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVD---GPTGQFNQTVITQAPAGVTEDDV 655 + V DEGVGPV TPIMRWL+ + G T QFNQTV+ QAPAGVTE +V Sbjct: 1015 ARVVGSGDGAAEVADEGVGPVPPTPIMRWLQAAERAGGATDQFNQTVLVQAPAGVTETEV 1074 Query: 656 VVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARN 715 ++LQAL+DRHA LRLRV D + D WS VPEAG+V AR+CLR+VDAL+D+ L+ AR Sbjct: 1075 AIVLQALVDRHAMLRLRVTD--DGADGWSFEVPEAGSVQARDCLRSVDALSDEALLAARA 1132 Query: 716 RLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAG 775 RL+PAAG M++A+WV T QL ++IHHLAVD VSW ILLEDLNIAWA H GQ +EL Sbjct: 1133 RLNPAAGTMLAALWVEATGQLAVIIHHLAVDAVSWWILLEDLNIAWALHRAGQPVELAPA 1192 Query: 776 GTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVE 835 GTSFARW+ LL EHA+ V D W+ VTS P ALP +PD DTY +AG+LS LD E Sbjct: 1193 GTSFARWARLLDEHARDPEVVGQLDRWKTVTSTPAALPAPRPDVDTYASAGRLSVELDAE 1252 Query: 836 TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLS 895 TT LLGEVPAAF AG+ DILL+AFGLAWTEFL PIG+DVEGHGR++EL + +DLS Sbjct: 1253 TTAMLLGEVPAAFHAGIHDILLIAFGLAWTEFLGEPGAPIGIDVEGHGRHEELGAGIDLS 1312 Query: 896 RTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPE 955 RTVGWFTTKYPV+L V L W QV AGD ALG ++K KEQLR+LPE LTYGLLRYLN + Sbjct: 1313 RTVGWFTTKYPVSLDVAGLRWPQVAAGDPALGPVLKRAKEQLRTLPEPLTYGLLRYLNTD 1372 Query: 956 VDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGT 1015 VDL G+DP+I FNYLGR GA A + + + WRI VPMPLMH VELNAGT Sbjct: 1373 VDLAGADPSIAFNYLGRQGA-ASDSAADGWRISH-DMSVLGAAAAVPMPLMHAVELNAGT 1430 Query: 1016 IDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARL 1075 IDT GP L A WTWAPS EQ TR+SRLWFEALAG+CAHVR GGGGLTPSD+APARL Sbjct: 1431 IDTGAGPHLHAEWTWAPSVLGAEQITRVSRLWFEALAGVCAHVRSGGGGLTPSDIAPARL 1490 Query: 1076 TQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIG--DDVYAVQLDITITGVLDQHR 1133 TQ+QIDEL R+ + D+LPLTP+QQGLLFHS+ A+G DD+YAVQLD T+TG LD R Sbjct: 1491 TQQQIDELQSRHRIADILPLTPLQQGLLFHSSTAQGNDGMDDMYAVQLDFTLTGPLDADR 1550 Query: 1134 LRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDL-RGDDLTPDHEIEQLCA 1192 LR+AV TVV RHP+LAA F +Q+ EPVQ++ ADP + WRY++L R D IEQLCA Sbjct: 1551 LREAVRTVVHRHPHLAALFCDQYDEPVQIIPADPAVEWRYVELDRTGAADADDPIEQLCA 1610 Query: 1193 AERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLP 1252 AER+AV DL +P FR AL+RT G++HRFVLT HHI++DGWSLPILL+EIFAGY+G RLP Sbjct: 1611 AERAAVGDLAGQPVFRTALVRTGGDRHRFVLTSHHILLDGWSLPILLREIFAGYYGQRLP 1670 Query: 1253 AAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG--VPGPRGIESYRVSAETT 1310 AA YR F+ WL W EVL GF+TPTLVAP G G RG E V +TT Sbjct: 1671 AAGSYRAFLTWLAERDLDAARRAWGEVLSGFDTPTLVAPEGRLGQGRRGFEKSCVPEQTT 1730 Query: 1311 RALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSG-RPADLAGAESMVGLLI 1369 RALGELARS HTT++TVLQAAW +L +TG+ DV FGT S ++ AE MVGLLI Sbjct: 1731 RALGELARSCHTTLSTVLQAAWAVVLTSLTGRHDVVFGTPRSRVGQLEVDDAEQMVGLLI 1790 Query: 1370 NTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYP 1429 NTVP+RA+++A TT LL QLQ+ HNDTLEH+HLAL++IH V+GH+QLFDTLF+YE+YP Sbjct: 1791 NTVPVRAEITATTTTAQLLAQLQNSHNDTLEHQHLALSEIHRVTGHDQLFDTLFVYENYP 1850 Query: 1430 IDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRF 1489 ID+ +G LA+ EF NREYNHYPL+V ALPG ELGL +E+DT VFD + IE+L+ R Sbjct: 1851 IDSGMTLGADGLAIAEFTNREYNHYPLTVEALPGPELGLHIEFDTDVFDTASIESLVQRL 1910 Query: 1490 QRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDP 1549 QR+L AM DPARRLSS+D++D ER + + A ++ P+ P++ A V DP Sbjct: 1911 QRVLVAMSTDPARRLSSLDLLDRGERELVLSTMSGAGVSAPIG---VAPQLLAAAVAADP 1967 Query: 1550 EAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTG 1609 +APA+ L+Y ELDE + +LA L +G P ++V + + R A+ +VA AV K G Sbjct: 1968 DAPAIVDGARELSYRELDEWSTRLARKLIQHGVGPERAVGVAIERCAELVVAWWAVTKAG 2027 Query: 1610 AAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLR---------SRFDGFDLQVVEVDDPA 1660 Y P++ P R+ +L V +T G R DG DL + Sbjct: 2028 GVYAPVNLDHPVERVASVLHTVDAVCVLTCGTDEVAGAGPRPILRIDGLDLSGHSTE--- 2084 Query: 1661 VEIYPSTTLLTPSP---DDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGA 1717 P T SP DD AY+I+TSG+TGVPKGVA++H + G A Sbjct: 2085 ----PITDADRRSPLRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGADA 2140 Query: 1718 VWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAV 1777 S FD SV E+ A G L++ P + + L ALL ++ V TP+ + Sbjct: 2141 RVLMVASPTFDASVGELLLAAGSGAALIVAPPQVYAG-EALTALLHNQRVGTAILTPTVI 2199 Query: 1778 RMMSPEGLEGT-ALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDV 1836 + L+G LV GEAC E+VD WA R M N YGP+E+TI+ A L+ G Sbjct: 2200 STLDRGRLDGLHTLVAVGEACLPELVDGWAPGRQMFNGYGPSETTIWVT-CARLTAGQP- 2257 Query: 1837 VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEP 1896 V IG+P+P VLD WL+PVP GVVGELYL+ LT RFVA PFG P Sbjct: 2258 VRIGAPIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERFVANPFGGP 2317 Query: 1897 GARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARE 1956 G RMYRTGDLVRW +G L YLGRAD Q+K+RG RIELGEI+ L V QA V ++ Sbjct: 2318 GERMYRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAAVTVQD 2377 Query: 1957 DRPGDKRLVGYITGTADPAAA 1977 G +LV Y+T P+ A Sbjct: 2378 SAAG-SQLVAYVTLDHGPSDA 2397 Score = 851 bits (2198), Expect = 0.0 Identities = 490/1055 (46%), Positives = 640/1055 (60%), Gaps = 53/1055 (5%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ Q L F F +Y + + + ++G LD LR A+ VVARH +L Sbjct: 2945 VIPLSFAQTRLWFIDQFQGP--SPMYNITVALRLSGRLDADALRAALADVVARHESLRTV 3002 Query: 1152 FVEQFGEPVQVLTADPMIAWR--YLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 F G P QV+ I + +D RG P+ + + +A DL Sbjct: 3003 FATADGTPQQVVIPADRIGFACDVVDARG---WPEDRLREAMSAAARYTFDLSAESPLHT 3059 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVN 1262 L ++H V+ HHI DGWS+ +++ Y R P AP Y ++ Sbjct: 3060 ELFARGDDEHVLVVAVHHIAADGWSITPFARDLGVAYASRCVGRDPDWAPLPVQYADYTL 3119 Query: 1263 WLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAE 1308 W W + L G + PT P V RG + AE Sbjct: 3120 WQRAHLGDVDDPGSRIAAQLDFWTDALAGLPERLQLPTDRPYPAVADHRGARLAVDWPAE 3179 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLL 1368 + L +AR + T V+QAA+ LL +++ DVA G ++GRP + + ++G Sbjct: 3180 LQQQLRRVAREHNATSFMVVQAAFAALLAKVSASSDVAVGFPIAGRPEPVL--DELIGFF 3237 Query: 1369 INTVPIRA---KVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQL 1418 +NT+ +R ++ D T +LL Q++ EH+ + LN +S H L Sbjct: 3238 VNTLVLRVDLNELGGDPTFAELLAQVRRRSLAAFEHQDVPFELLVERLNPTRSMS-HHPL 3296 Query: 1419 FDTLFLYESYPIDTSA---FMGVQELAVTEF---NNREYNHYPLSV---MALPGHELGLR 1469 L +E++P + +A + + +L VT N S+ G G+ Sbjct: 3297 VQVLLGWENFPGEVTAPAAGLALGDLQVTPMPLHTNTARMDLTFSLAERFTESGQRAGIA 3356 Query: 1470 V--EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 V EY T VFD +E LI+R QRLL A+ DP RRLS++D++D +E +L++W N AVL Sbjct: 3357 VTAEYRTDVFDGRTVEGLIERLQRLLTAVTADPQRRLSAVDLLDANEHARLEKWGNTAVL 3416 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 +P +P S+P FA Q R P+A A+T +G S+ Y ELDEAAN+LA+ + +GA PG+ Sbjct: 3417 ARPA-TPVSVPTRFAAQAARTPDAVALTCDGRSMTYRELDEAANRLAHFMIHHGAGPGER 3475 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VAL+ PRSA+AIVAILA LK+GAAYLPIDP++PAAR+EFML DA P+ AVTT L R Sbjct: 3476 VALLFPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIVAVTTAALAERLH 3535 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 GFDL V++V DPAV P+T P PDD+A++IYTSGTTGVPKGVA+T NV Q+ D L Sbjct: 3536 GFDLTVIDVADPAVATQPATAPPVPDPDDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDL 3595 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 + P VW+Q+HS FD SVWEIWGALLHGGRLV+VPE+++ SP++ H LLV E V Sbjct: 3596 RIGIELSPRQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPETVSRSPNEFHDLLVREHV 3655 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAIS 1827 VL QTPSAV ++ +GL+GTALV+ E CP E+VDRWA R M+N YGPTE+T++A S Sbjct: 3656 TVLTQTPSAVGLLRTDGLDGTALVIGAEPCPPELVDRWAPGRTMVNVYGPTETTMWACKS 3715 Query: 1828 APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTR 1887 APL+ GS PIG+PV + A FVLD+WLRPVPPGVVGELYLA LT R Sbjct: 3716 APLTAGSGFPPIGAPVTRAAFFVLDDWLRPVPPGVVGELYLAGDGVGVGYWRRPGLTAAR 3775 Query: 1888 FVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGV 1947 F+ACPFGEPG RMYRTGDLVRW DGQL YLGRADEQVK+RGYRIELGEIQAALS +DGV Sbjct: 3776 FLACPFGEPGTRMYRTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGV 3835 Query: 1948 DQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGK 2007 +QAVV+ARED PGDKRLVGY+TG+ PA AR+ L RLPAYMVPAAVV L++LP+TVNGK Sbjct: 3836 EQAVVVAREDNPGDKRLVGYVTGSVAPAKARAALAERLPAYMVPAAVVVLDSLPMTVNGK 3895 Query: 2008 LDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRV 2067 LD RALPAP+Y+ YRAPE+ TE+ LAGI+A VLGV+R MR+ Sbjct: 3896 LDTRALPAPDYRHTGGYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRL 3955 Query: 2068 TAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 A+N+ALD DL VRT+FEAPT+A+L+ + AG Sbjct: 3956 ITAINSALDTDLPVRTVFEAPTIAQLAPRIAQSAG 3990 Score = 837 bits (2162), Expect = 0.0 Identities = 512/1093 (46%), Positives = 658/1093 (60%), Gaps = 71/1093 (6%) Query: 1045 RLWFEA--LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGL 1102 R FEA +A + + GGL P A + DV+PL+ Q L Sbjct: 3970 RTVFEAPTIAQLAPRIAQSAGGLAPLVAA----------------ERPDVVPLSFAQNRL 4013 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 F F +Y + + + G LD L A+ VVARH +L F G P Q+ Sbjct: 4014 WFIDQFQGP--SPLYNMAAALRLRGRLDAGALGAALADVVARHESLRTVFPSHQGTPRQL 4071 Query: 1163 LTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFV 1222 + + + + D D + + R DL RA L S ++H V Sbjct: 4072 VVPAERAEFGWDVIDATDWPADRLDDAVQDVTRHTF-DLAAEIPIRAKLFAVSEDEHVLV 4130 Query: 1223 LTFHHIVIDGWSLPIL---LQEIFAGYFGHRLPAAAP----YRNFVNWLXXXXXXXXXXX 1275 + HHI DG SL L L + +A P A Y ++ W Sbjct: 4131 IVVHHIAADGMSLTPLGVDLSQAYASRCAGHAPGWADLPVQYCDYTLWQRAQFGDLDDPD 4190 Query: 1276 ---------WREVLDGFET----PTLVAPPGVPGPRGIESYRVS--AETTRALGELARSQ 1320 W++ L G PT P V RG +S V AE + + +AR Sbjct: 4191 SRIGTQLAYWQDALAGMPERLALPTDRPYPAVADQRG-DSVAVDWPAELQQQVRRVAREH 4249 Query: 1321 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAKV 1378 + T V+QAA LL ++ DVA G ++GR PA + +VG +NT+ +R + Sbjct: 4250 NATSFMVVQAALAVLLSKIGASSDVAVGFPIAGRRDPA----LDRLVGFFVNTLVLRIDL 4305 Query: 1379 SADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYP-- 1429 + D + +LL ++Q+ EH+ + LN ++ H L + ++++ Sbjct: 4306 TGDPSFAELLARVQARSLAAFEHQDVPFEVLVERLNPTRSLT-HHPLVQVMLAWQNFAGH 4364 Query: 1430 IDTSAFMGVQELAVTEFNNREYNHYPLSVMAL-----PGHE---LGLRVEYDTSVFDVSE 1481 D +A + + +L VT + + V +L P E +G RVE+ T VFD + Sbjct: 4365 DDPAAALALGDLDVTSVPVHDQSARMDLVFSLAERWNPDGEFAGIGGRVEFRTDVFDAAT 4424 Query: 1482 IETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVF 1541 IETLI+R +R+LEAM DP R LS++D++DD ER L+E N A+LT+P S+PE+F Sbjct: 4425 IETLIERLRRVLEAMTGDPGRPLSAVDLLDDAERAYLEEVGNTAILTRPASGRVSVPELF 4484 Query: 1542 ARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVA 1601 A QV R PE A+ + S+ Y +LDEA+N+LA+ LA GA PG++VAL+ RSA+A+ A Sbjct: 4485 ATQVARVPETVALVCDDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAA 4544 Query: 1602 ILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAV 1661 ILAVLKTGAAYLPIDPS P R+EFMLGDA+P+AAVTT +L R G + VV+VDDP + Sbjct: 4545 ILAVLKTGAAYLPIDPSAPQTRVEFMLGDAEPIAAVTTAELAQRLAGRPVTVVDVDDPGI 4604 Query: 1662 EIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQ 1721 + P T L P PD IAY+IYTSGTTG PKGVA+TH NVTQ+L +L A LP+ PG VWSQ Sbjct: 4605 DTLPDTALPLPDPDGIAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPS-PG-VWSQ 4662 Query: 1722 WHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS 1781 HSL FDVSVWEI+GALL GGR+V++PE++A SP DLH L++ V VL QTPSA+ M+S Sbjct: 4663 CHSLAFDVSVWEIFGALLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSALAMLS 4722 Query: 1782 PEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGS 1841 P+GLE +LV+AGEACP EVVD+WA RVM+N YGPTE+++ +ISAPL+ GS + PIGS Sbjct: 4723 PQGLESVSLVLAGEACPPEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGS 4782 Query: 1842 PVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMY 1901 PV A FVLDE LRPVPPGVVGELY+A LT RFVACPFG P ARMY Sbjct: 4783 PVDGAALFVLDESLRPVPPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPSARMY 4842 Query: 1902 RTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGD 1961 RTGDLVRW DGQL YLGRADEQVK+RGYRIELGEIQAALS +DGV+QAVV+ARED PGD Sbjct: 4843 RTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGD 4902 Query: 1962 KRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSA 2021 KRLVGYITGTADPA AR+ L RLPAYMVPAAV+ L+ +PLT NGKLD RALPAP+Y +A Sbjct: 4903 KRLVGYITGTADPAEARARLGERLPAYMVPAAVLGLDAIPLTPNGKLDARALPAPDY-AA 4961 Query: 2022 QRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSV 2081 YRAP+T TE+ LAGI+A VLGV+R AMR+ AAVN AL+ADL V Sbjct: 4962 GEYRAPQTPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPV 5021 Query: 2082 RTLFEAPTVAKLS 2094 RT+FEAPTVA L+ Sbjct: 5022 RTVFEAPTVAALA 5034 Score = 814 bits (2102), Expect = 0.0 Identities = 502/1098 (45%), Positives = 639/1098 (58%), Gaps = 79/1098 (7%) Query: 1045 RLWFEA--LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGL 1102 R FEA +A + + GG GL P + V+PL+ Q L Sbjct: 5022 RTVFEAPTVAALAPRIGEGGSGLEPLTAG----------------ERPAVVPLSFAQNRL 5065 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 F VY + + + G LD L A+ VVARH +L F G P QV Sbjct: 5066 WFLDQLQGP--SPVYNMAAALRLDGPLDTEALGAALGDVVARHESLRTLFAAPEGRPQQV 5123 Query: 1163 LTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHR 1220 + W +D G ++++ A DL + RA L R ++H Sbjct: 5124 VLPAERADFGWEVVDASGWSAD---QLDEAIGATARYTFDLAAQIPLRAELFRLHDDRHV 5180 Query: 1221 FVLTFHHIVIDGWSLPILLQEIFAGYF----GHRL---PAAAPYRNFVNWLXXXXXXXXX 1273 V HHI DG S+ L++++ A Y GH P Y ++ W Sbjct: 5181 LVAVVHHIAADGMSITPLVRDLGAAYARRCAGHAPGWEPLPVQYVDYTLWQRAQFGDLDD 5240 Query: 1274 XX---------WREVLDGFET----PTLVAPPGVPGPRGIE-SYRVSAETTRALGELARS 1319 W++ L G PT P V RG AE + +G++AR Sbjct: 5241 PGSRIAAQLAYWQDALAGMPERLALPTDRPYPLVADQRGATVEIDWPAELQQRIGDMARR 5300 Query: 1320 QHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAK 1377 + T V+Q A T LL ++ DVA G ++GR PA + +VG +NT+ +R Sbjct: 5301 HNATSFMVIQTALTVLLAKLGANPDVAVGFPIAGRRDPA----LDDLVGFFVNTLVLRVD 5356 Query: 1378 VSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYP- 1429 + D + +LL ++++ + EH+ + LN ++ H L + ++++ Sbjct: 5357 AAGDPSFTELLARVRTRSLEAFEHQDVPFEVLVERLNPTRSLT-HHPLVQVMLAWQNFAG 5415 Query: 1430 IDTSAFMG-------VQELAVTEFNNREYNHYPL----SVMALPGHELGLRVEYDTSVFD 1478 DT G + + V R + + S PG +G VE+ T VFD Sbjct: 5416 QDTGPAAGLSLGDVEITPIPVDTHTARMDLTFSVGERWSESGEPGG-IGGTVEFRTDVFD 5474 Query: 1479 VSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIP 1538 I+TLI R +R+LEAM DP + +SS+D++D+ E +LD NRA LT P S+P Sbjct: 5475 PDSIQTLIGRLRRVLEAMTADPTQSVSSVDLLDEREHARLDTLGNRAALTGPPPRFDSLP 5534 Query: 1539 EVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADA 1598 +FA Q R P+A A+ G + Y ELDEAAN++A+LL V GA PG +VAL+ RSA+A Sbjct: 5535 TLFAEQAARTPDAVALVCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVALLFSRSAEA 5594 Query: 1599 IVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDG-FDLQVVEVD 1657 IVAIL VLK+GAAYLPIDP++P R+ FML DA P+ A++T +L R G D+ VV+V Sbjct: 5595 IVAILGVLKSGAAYLPIDPALPGERIGFMLADAAPLVAISTAELAPRLHGQHDVPVVDVH 5654 Query: 1658 DPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGA 1717 DPA+E PS+ L P DDIAY+IYTSGTTGVPKGVA++H NV Q+L T + LP Sbjct: 5655 DPAIEAAPSSALPPPGADDIAYLIYTSGTTGVPKGVAVSHRNVAQLL-TAESGLPR--EG 5711 Query: 1718 VWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAV 1777 VWSQWHSL FDVSVWEI+GA LHGGRLV++PES+A SP+DLHALL++E V+VL QTPSA Sbjct: 5712 VWSQWHSLAFDVSVWEIFGAQLHGGRLVVIPESVARSPEDLHALLITEQVSVLSQTPSAA 5771 Query: 1778 RMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGS-DV 1836 +SPEGLE LVVAGEACP+E+VDRWA R MINAYGPTE+T+YAAISAPL PG+ Sbjct: 5772 GALSPEGLEDLTLVVAGEACPSELVDRWAPGRTMINAYGPTEATVYAAISAPLRPGALGG 5831 Query: 1837 VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEP 1896 VPIGSPVP GA FVLDEWLRPVPPGVVGELY+A LT +RFVACPFG P Sbjct: 5832 VPIGSPVPGGAVFVLDEWLRPVPPGVVGELYVAGAGVACGYWRRGGLTASRFVACPFGAP 5891 Query: 1897 GARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARE 1956 GARMYRTGDLVRW DGQL YLGR DEQVKIRGYRIELGE++AAL+ VDGVDQAVV+ARE Sbjct: 5892 GARMYRTGDLVRWRGDGQLDYLGRVDEQVKIRGYRIELGEVRAALAWVDGVDQAVVVARE 5951 Query: 1957 DRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAP 2016 DRP DKRLVGYITGTADPAA R+ L RLPAYMVPAAVVTL+ +PLT NGKLD RALPAP Sbjct: 5952 DRPRDKRLVGYITGTADPAAVRAALAERLPAYMVPAAVVTLDAIPLTPNGKLDTRALPAP 6011 Query: 2017 EYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALD 2076 EY A RYRAP+ E+ LAGI+A VLGV+R +M+V A Sbjct: 6012 EYSDADRYRAPDNAVEEILAGIYAQVLGVQRVGVDDSFFDLGGDSISSMQVVTRARAA-G 6070 Query: 2077 ADLSVRTLFEAPTVAKLS 2094 R +F TVA+L+ Sbjct: 6071 LVCKTRDIFVEQTVARLA 6088 Score = 813 bits (2100), Expect = 0.0 Identities = 497/1051 (47%), Positives = 630/1051 (59%), Gaps = 65/1051 (6%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ Q L F VY + + + G LD L A+ VVARH +L Sbjct: 7599 VVPLSFAQSRLWFLDQLQGP--SPVYNMAAALRMHGRLDDRALGAALADVVARHESLRTV 7656 Query: 1152 FVEQFGEPVQVLTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 F G P QV+ + WR ++ R D + E + AA R DL + RA Sbjct: 7657 FAAPDGTPQQVVLPAERADLGWRVVNAR--DWSASRLREAIDAAARETF-DLATQIPLRA 7713 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYF----GHRL---PAAAPYRNFVN 1262 L R ++H V HHI DGWSL L++++ Y GH P Y ++ Sbjct: 7714 TLFRIGEDEHVLVAVVHHIAADGWSLRPLVRDLGVAYASRCAGHAPGWEPLPVQYVDYTL 7773 Query: 1263 WLXXXXXXXXXXX---------WREVLDGFETPTLVAPPGVPGPRGIESYRVS------A 1307 W W++ L G L P P P+ + + A Sbjct: 7774 WQRAQFGELADSGSRIAAQLAYWQQALAGMPE-RLALPTDRPYPQLADQRGAAVDVDWPA 7832 Query: 1308 ETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMV 1365 + + + LAR ++T V+QAA LL +++ DVA G ++GR PA + +V Sbjct: 7833 DLQQQVAGLAREYNSTSFMVVQAALAVLLAKLSASTDVAVGFPIAGRRDPA----LDDLV 7888 Query: 1366 GLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQL 1418 G +NT+ +R +S D + +LL ++++ + EH+ + LN ++ H L Sbjct: 7889 GFFVNTLVLRVDLSGDPSFTELLARVRTRSLEAFEHQDVPFEVLVERLNPTRSLT-HHPL 7947 Query: 1419 FDTLFLYESYP---IDTSAFMGV-QELAVTEFN-----NREYNHYPLSVMALPGHE---L 1466 + ++++ D A + + ++ VT R + L+ E + Sbjct: 7948 VQVMLAWQNFAGQDADPGAGLALGDDVRVTSMPLDTQVARMDLTFSLAERWTEDDEPAGI 8007 Query: 1467 GLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAV 1526 G RVE+ T VFD IETLI R QR+LEAM DP + +SS+D++D E LD NRA Sbjct: 8008 GGRVEFRTDVFDADTIETLIRRLQRVLEAMTADPTQSVSSVDLLDAGEHAHLDRIGNRAA 8067 Query: 1527 LTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGK 1586 L+ P SIP VFA Q R P+A A+ +E S Y ELDEAAN+LA+ LA +G G+ Sbjct: 8068 LSGPAAQFHSIPTVFAEQAARTPDAVALVYEDRSWTYRELDEAANRLAHRLAGFGVGAGE 8127 Query: 1587 SVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRF 1646 VAL+ RSA+AIVAILAVLK GAAYLPIDP++P R+ FML DA P+ A++T +L R Sbjct: 8128 RVALLFSRSAEAIVAILAVLKAGAAYLPIDPALPDERIGFMLADAAPMVAISTAELAPRL 8187 Query: 1647 DGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDT 1706 G + V++V DPAV+ PST L P DDIAY+IYTSGTTGVPKGVA++H NVTQ+L T Sbjct: 8188 HGHHVVVLDVHDPAVDTQPSTPLPPPGADDIAYLIYTSGTTGVPKGVAVSHRNVTQLL-T 8246 Query: 1707 LPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEG 1766 + LP VWSQWHSL FDVSVWEI+GALLHGGRLV++P+S+ SPDD HALLV E Sbjct: 8247 ADSGLPR--EGVWSQWHSLAFDVSVWEIFGALLHGGRLVVIPDSVVRSPDDFHALLVDEQ 8304 Query: 1767 VNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAI 1826 V+VL QTPSA +SPEGLE TALVVAGEACP E+VDRWA R MINAYGPTE+T+Y AI Sbjct: 8305 VSVLSQTPSAAGTLSPEGLESTALVVAGEACPAELVDRWAPGRTMINAYGPTEATVYTAI 8364 Query: 1827 SAPLSPGSDV-VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTG 1885 SAPL PGS VPIG PVP FVLDE LRPVPPGVVGELY+A LT Sbjct: 8365 SAPLQPGSPAGVPIGFPVPGTGLFVLDESLRPVPPGVVGELYVAGAGVACGYWRRGGLTA 8424 Query: 1886 TRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVD 1945 +RFVACPFG PGARMYRTGDLVRW DGQL YLGRADEQVK+RGYRIELGE+++AL+ +D Sbjct: 8425 SRFVACPFGRPGARMYRTGDLVRWRGDGQLDYLGRADEQVKVRGYRIELGEVRSALAALD 8484 Query: 1946 GVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVN 2005 GVDQA V+AREDRPGDKRLVGYITG ADPA AR+ L RLPAYMVPAA+V L+ +PLT N Sbjct: 8485 GVDQAAVVAREDRPGDKRLVGYITGDADPAEARARLGERLPAYMVPAAIVALDAIPLTPN 8544 Query: 2006 GKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAM 2065 GKLD RALPAPEY A +YRAPET E+TLA I+A VLGV+R +M Sbjct: 8545 GKLDTRALPAPEYSDAGQYRAPETPVEQTLAAIYAQVLGVQRVGVDDSFFDLGGDSISSM 8604 Query: 2066 RVTAAVNTALDADLSVRT--LFEAPTVAKLS 2094 +V V A A L+VRT +F TVA+L+ Sbjct: 8605 QV---VTRAKAAGLAVRTRDIFTEQTVARLA 8632 Score = 760 bits (1962), Expect = 0.0 Identities = 448/926 (48%), Positives = 570/926 (61%), Gaps = 42/926 (4%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L + DLLD+ E +E GN A+LT P V++P LFA QV R P+ VAL Sbjct: 4439 MTGDPG-RPLSAVDLLDDAERAYLEEVGNTAILTRPASGRVSVPELFATQVARVPETVAL 4497 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V D S TYR+LDEASNRLAH LA GA PG TVA L RS EA+ +IL+VLKTGAAYLP Sbjct: 4498 VCDDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAAILAVLKTGAAYLP 4557 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP+ P R+ FM+ DA+P+AA+TTA+L RL + V+D+ DP ID P AL P P Sbjct: 4558 IDPSAPQTRVEFMLGDAEPIAAVTTAELAQRLAGRPVTVVDVDDPGIDTLPDTALPLPDP 4617 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D +AY+ YTSGTTG PK VAVTHHNVTQL+ +L A LPS PG VWSQ HSL FDVSVWEI Sbjct: 4618 DGIAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPS-PG-VWSQCHSLAFDVSVWEI 4675 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALL GGR+VV+PE+V SP DLH+ LI V+VL QTPSA MLSP+GLES +L++AG Sbjct: 4676 FGALLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSALAMLSPQGLESVSLVLAG 4735 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP E+VD+WAPGRVM+N YGPTE ++ ++S PL LFVLD+ Sbjct: 4736 EACPPEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVDGAALFVLDES 4795 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELYVAG GVA GY+GRP LTA+RFVACPFG RMYRTGDLVRW +DGQ Sbjct: 4796 LRPVPPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPSARMYRTGDLVRWRADGQ 4855 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L+YLGRADEQVK+RGYRIELGEIQAAL+ LDGV+QAVV+ARED PGDKRLVGYITGTADP Sbjct: 4856 LDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYITGTADP 4915 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A+ R L E LPAYMVP AV+ LD IPLT NGKLD RALPAP+Y AA +YRAP TP E+ Sbjct: 4916 AEARARLGERLPAYMVPAAVLGLDAIPLTPNGKLDARALPAPDY--AAGEYRAPQTPTEE 4973 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXX 599 ILA +YA+VLGV+RVGVDDSFFDLGGDSI +M+++A AA R +F T Sbjct: 4974 ILAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPVRTVFEAPTVAAL 5033 Query: 600 XXXXXXXXES-HVVDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTED 653 + G P V A + +L ++ GP+ +N + + + Sbjct: 5034 APRIGEGGSGLEPLTAGERPAVVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDGPLDTE 5093 Query: 654 DVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR----TVDALTDDV 709 + L ++ RH +LR + + +++P A E + + D L + + Sbjct: 5094 ALGAALGDVVARHESLRTLFAAPEGRPQQ--VVLPAERADFGWEVVDASGWSADQLDEAI 5151 Query: 710 LVEARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCT 766 AR D AA + A R + LV ++HH+A DG+S L+ DL A+A+ C Sbjct: 5152 GATARYTFDLAAQIPLRAELFRLHDDRHVLVAVVHHIAADGMSITPLVRDLGAAYARRCA 5211 Query: 767 GQS---IELPAGGTSFARWSALLAEHAKTD-----TVRDLADAWRAVTSVPQALPPVQPD 818 G + LP + W A+ D LA A+ +P+ L + D Sbjct: 5212 GHAPGWEPLPVQYVDYTLWQR--AQFGDLDDPGSRIAAQLAYWQDALAGMPERL-ALPTD 5268 Query: 819 TDTYVTAGQLSASLDVE---TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPI 875 + A Q A+++++ +Q +G++ A ++ A + + D + Sbjct: 5269 RPYPLVADQRGATVEIDWPAELQQRIGDMARRHNATSFMVIQTALTVLLAKLGANPDVAV 5328 Query: 876 GVDVEGHGRYDELASDVDLSRTVGWF 901 G + G D L VG+F Sbjct: 5329 GFPIAGR-------RDPALDDLVGFF 5347 Score = 759 bits (1960), Expect = 0.0 Identities = 443/930 (47%), Positives = 568/930 (61%), Gaps = 48/930 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+P R L + DLLD +EH ++E WGN AVL P TPV++P FA Q R PDAVAL Sbjct: 3385 VTADPQRR-LSAVDLLDANEHARLEKWGNTAVLARPA-TPVSVPTRFAAQAARTPDAVAL 3442 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS TYRELDEA+NRLAH + HGA PG VA L PRS EAI++IL+ LK+GAAYLP Sbjct: 3443 TCDGRSMTYRELDEAANRLAHFMIHHGAGPGERVALLFPRSAEAIVAILAALKSGAAYLP 3502 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P AR+ FM++DA P+ A+TTA L RL +DL VID+ADPA+ +P+ A P P Sbjct: 3503 IDPALPAARVEFMLTDAAPIVAVTTAALAERLHGFDLTVIDVADPAVATQPATAPPVPDP 3562 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+A++ YTSGTTGVPK VAVT +NV QL L + P QVW+Q+HS FD SVWEI Sbjct: 3563 DDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDLRIGIELSPRQVWTQFHSYAFDFSVWEI 3622 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPE+V SP++ H+LL+ E V+VL QTPSA G+L +GL+ T L++ Sbjct: 3623 WGALLHGGRLVVVPETVSRSPNEFHDLLVREHVTVLTQTPSAVGLLRTDGLDGTALVIGA 3682 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 E CP ELVDRWAPGR M+N YGPTE T++A S PL FVLD W Sbjct: 3683 EPCPPELVDRWAPGRTMVNVYGPTETTMWACKSAPLTAGSGFPPIGAPVTRAAFFVLDDW 3742 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELY+AG GV GY RP LTA+RF+ACPFGE G RMYRTGDLVRW +DGQ Sbjct: 3743 LRPVPPGVVGELYLAGDGVGVGYWRRPGLTAARFLACPFGEPGTRMYRTGDLVRWRADGQ 3802 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L+YLGRADEQVK+RGYRIELGEIQAAL+ LDGV+QAVV+ARED PGDKRLVGY+TG+ P Sbjct: 3803 LDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYVTGSVAP 3862 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A+ R ALAE LPAYMVP AVVVLD++P+TVNGKLD RALPAP+YR YRAP +P E+ Sbjct: 3863 AKARAALAERLPAYMVPAAVVVLDSLPMTVNGKLDTRALPAPDYRHTGG-YRAPESPTEE 3921 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRP-RDIFVEQTXXXX 599 ILA +YA+VLGV+RVGVDDSFFDLGGDS+ +M+++ +A P R +F T Sbjct: 3922 ILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRLITAINSALDTDLPVRTVFEAPTIAQL 3981 Query: 600 XXXXXXXXESHVVDEGVGPVVA------TPI------MRWLREVDGPTGQFNQTVITQAP 647 G+ P+VA P+ + ++ + GP+ +N + Sbjct: 3982 APRIAQSA------GGLAPLVAAERPDVVPLSFAQNRLWFIDQFQGPSPLYNMAAALRLR 4035 Query: 648 AGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRT----VD 703 + + L ++ RH +LR V + + T L+VP A + + D Sbjct: 4036 GRLDAGALGAALADVVARHESLR-TVFPSHQGTPR-QLVVPAERAEFGWDVIDATDWPAD 4093 Query: 704 ALTDDVLVEARNRLDPAAGAMVSA---VWVRETSQLVLMIHHLAVDGVSWRILLEDLNIA 760 L D V R+ D AA + A + LV+++HH+A DG+S L DL+ A Sbjct: 4094 RLDDAVQDVTRHTFDLAAEIPIRAKLFAVSEDEHVLVIVVHHIAADGMSLTPLGVDLSQA 4153 Query: 761 WAQHCTGQS---IELPAGGTSFARWS-ALLAEHAKTDT--VRDLADAWRAVTSVPQALPP 814 +A C G + +LP + W A + D+ LA A+ +P+ L Sbjct: 4154 YASRCAGHAPGWADLPVQYCDYTLWQRAQFGDLDDPDSRIGTQLAYWQDALAGMPERL-A 4212 Query: 815 VQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFR---AGVQDILLVAFGLAWTEFLNRS 871 + D A Q S+ V+ +L +V R A ++ A + ++ S Sbjct: 4213 LPTDRPYPAVADQRGDSVAVDWPAELQQQVRRVAREHNATSFMVVQAALAVLLSKIGASS 4272 Query: 872 DTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 D +G + G D L R VG+F Sbjct: 4273 DVAVGFPIAGR-------RDPALDRLVGFF 4295 Score = 756 bits (1952), Expect = 0.0 Identities = 453/923 (49%), Positives = 562/923 (60%), Gaps = 35/923 (3%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P+ R L S D+LD EH ++ WG RAVL P T +IPALF Q R+P A A+ Sbjct: 6982 MTADPA-RPLSSIDVLDPAEHQRLHDWGARAVLDRPA-TRTSIPALFTAQAQRSPQAPAV 7039 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 R+ TYRELDEASNRLAH+L G PG VA L+PRS +AI++IL+VLKTGAAYLP Sbjct: 7040 TFEGRTTTYRELDEASNRLAHLLIGRGVGPGQAVALLLPRSADAIVAILAVLKTGAAYLP 7099 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P ARI FM+ D P AA+TTA L L DL V+D+ D A+ R+P AL P P Sbjct: 7100 IDPALPAARIEFMLDDTAPTAAVTTAALAGPLRGRDLTVVDIGDRALSRQPHTALPAPDP 7159 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D +A++ YTSGTTGVPK VAV+HHNVT+L A + QVW+Q+HS FD SVWEI Sbjct: 7160 DHVAHIIYTSGTTGVPKGVAVSHHNVTRLFDAQAVGVELSADQVWTQFHSYAFDYSVWEI 7219 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVV ++V SP D H LL+ E V+VL QTPSA MLSP+GLES L++ Sbjct: 7220 WGALLHGGRLVVVSDAVARSPMDFHALLVAENVTVLSQTPSAVRMLSPQGLESAALVIGA 7279 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 E CP EL+DRWAPGR M+N YGPTEATI++ S PL L VLD W Sbjct: 7280 EPCPPELLDRWAPGRTMVNVYGPTEATIFSTASTPLAAGSGAPPIGSPVPGTALLVLDGW 7339 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELYVAG GV GY+ R LTASRFVACPFG G RMYRTGDLVRW +DGQ Sbjct: 7340 LRPVPAGVVGELYVAGRGVGYGYLRRAGLTASRFVACPFGAPGARMYRTGDLVRWRADGQ 7399 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L+YLGRADEQVKIRGYRIE+GEI++ALA LDGVD+AVVIAREDRPGDKRLVGYITG ADP Sbjct: 7400 LDYLGRADEQVKIRGYRIEVGEIRSALAALDGVDEAVVIAREDRPGDKRLVGYITGDADP 7459 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A+ R LAE LPAYMVP AVVVLD +P+TVNGKLD RALPAPEY AA YR+P+TPAE+ Sbjct: 7460 AEARARLAERLPAYMVPVAVVVLDALPMTVNGKLDLRALPAPEY--AAAGYRSPTTPAEE 7517 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXX 599 ILA +YA VLGV+RVGVDDSFFDLGGDSI +M+V+A +A + R IF T Sbjct: 7518 ILAGIYAHVLGVQRVGVDDSFFDLGGDSISAMRVIAAINSALDVGVPVRAIFEAPTVAQL 7577 Query: 600 XXXXXXXX-ESHVVDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTED 653 + G P V A + +L ++ GP+ +N + + + Sbjct: 7578 APRIGEDAGRLDPLTAGERPAVVPLSFAQSRLWFLDQLQGPSPVYNMAAALRMHGRLDDR 7637 Query: 654 DVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR---TVDALTDDVL 710 + L ++ RH +LR V + T + +L E +G R + L + + Sbjct: 7638 ALGAALADVVARHESLRT-VFAAPDGTPQQVVLPAERADLGWRVVNARDWSASRLREAID 7696 Query: 711 VEARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTG 767 AR D A + A R + LV ++HH+A DG S R L+ DL +A+A C G Sbjct: 7697 AAARETFDLATQIPLRATLFRIGEDEHVLVAVVHHIAADGWSLRPLVRDLGVAYASRCAG 7756 Query: 768 QS---IELPAGGTSFARWS-ALLAEHAKTDT--VRDLADAWRAVTSVPQ--ALPPVQPDT 819 + LP + W A E A + + LA +A+ +P+ ALP +P Sbjct: 7757 HAPGWEPLPVQYVDYTLWQRAQFGELADSGSRIAAQLAYWQQALAGMPERLALPTDRPYP 7816 Query: 820 DTYVTAGQLSASLDVETTRQLLGEVPAAFRA-GVQDILLVAFGLAWTEFLNRSDTPIGVD 878 A Q A++DV+ L +V R ++V LA + T + V Sbjct: 7817 Q---LADQRGAAVDVDWPADLQQQVAGLAREYNSTSFMVVQAALAVLLAKLSASTDVAVG 7873 Query: 879 VEGHGRYDELASDVDLSRTVGWF 901 GR D D+ VG+F Sbjct: 7874 FPIAGRRDPALDDL-----VGFF 7891 Score = 728 bits (1878), Expect = 0.0 Identities = 442/993 (44%), Positives = 579/993 (58%), Gaps = 34/993 (3%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 + I G +D L A+ VV +L A F E G+ Q + + DL G Sbjct: 36 VRIDGAIDPALLHQAMRHVVGEAESLRASFFEADGQVFQKAVEYSDVDLTFYDLSGSP-D 94 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 P+ E+ ++ A+ + L P + AL RT ++ + T HHI IDG + ++ + I Sbjct: 95 PEREVREMAASIQRTPMPLTG-PMIKFALFRTGSAEYYWFTTCHHIAIDGMGIALVGRRI 153 Query: 1243 FAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAP-------PGVP 1295 A Y P F + + L+ + P P P Sbjct: 154 AAVYTALASAKPIPPAFFGSLQDLVGGELEYEASAKFLEDKDYWLAHRPGDGTAGHPPRP 213 Query: 1296 GPRGIESY------RVSAETTRALGELARSQHTTINTVLQAAWTQLLMR---MTGQRDVA 1346 G + Y ++ ++ EL+++ ++VL AA LL+R G +V Sbjct: 214 ADDGRDPYSPSPPVQLDESVIGSVKELSKALGVRRSSVLTAACA-LLVRGWCADGSDEVV 272 Query: 1347 FGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHL-- 1404 VS R + ++ G+L VP+ A T D R + + L H+ Sbjct: 273 LDFPVSRRVDPKS--KTHPGMLAGVVPLVLHAPATATFADFCRHVDQRSREALRHQQFPT 330 Query: 1405 -ALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPG 1463 L+ SG Q + + + P + + T + H+ L + Sbjct: 331 RTLDGEGDFSGPRQAPNRVVV-NFVPARLTLSLADVPATATYTSFGPVGHFGLFFLGFGD 389 Query: 1464 HELGLRVEYDTSV--FDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEW 1521 + V + FD ++ L +R QR+L AM DPAR LSS+DV+ D E QL+ Sbjct: 390 QQFLSTVGTGQPLANFDATD---LAERLQRILAAMAADPARLLSSLDVLRDPEHAQLEAL 446 Query: 1522 ANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYG 1581 N AVLT+ S+PE+FA QV R P+ A+ EG SL Y +LDEA+N+LA+LLA G Sbjct: 447 GNTAVLTRTPGPAVSVPELFATQVARAPQDVALVGEGRSLTYRQLDEASNRLAHLLAGLG 506 Query: 1582 AAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGD 1641 A PG+SVAL+ RSA+A+ +ILAVLKTGAAYLPIDP+ P R+ FML DAKPVAA++T + Sbjct: 507 AGPGQSVALLFSRSAEAVASILAVLKTGAAYLPIDPAAPETRIGFMLADAKPVAALSTAE 566 Query: 1642 LRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVT 1701 L R + + V++V+DP ++ P+T L + D +AY+IYTSGTTGVPKGVA+TH NVT Sbjct: 567 LAGRLEAHGMTVIDVNDPRIQDRPATALPVAAADGVAYVIYTSGTTGVPKGVAVTHRNVT 626 Query: 1702 QVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHAL 1761 Q+L +L A LP+ VWSQ HS FDVSVWEI+GALL GGRLV+VPE++ +P++LH + Sbjct: 627 QLLGSLDAGLPSA--GVWSQCHSYAFDVSVWEIFGALLRGGRLVVVPEAVTRAPEELHDV 684 Query: 1762 LVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTEST 1821 LV+E V+VL QTPSAV M+SP+GLE +LVV GEACP EVVDRW+ RVM+NAYGPTE+T Sbjct: 685 LVNEQVSVLTQTPSAVAMLSPQGLESVSLVVVGEACPAEVVDRWSGGRVMVNAYGPTETT 744 Query: 1822 IYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXX 1881 + AISAPL+PG PIG PV FVLD WLRPVPPGVVGELY+ Sbjct: 745 MCVAISAPLAPGMGSPPIGVPVDGAGLFVLDAWLRPVPPGVVGELYVGGAGVAAGYVGRS 804 Query: 1882 XLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAAL 1941 LT +RFVACPFG PGARMYRTGDLV W DGQL Y GRADEQVK+RGYRIELGE+QAAL Sbjct: 805 GLTASRFVACPFGAPGARMYRTGDLVCWRPDGQLDYRGRADEQVKVRGYRIELGEVQAAL 864 Query: 1942 SDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLP 2001 + +D V+QAVVIAREDRPG KRLVGYITGTADPA AR+ L RLP YMVPAAVV L+ +P Sbjct: 865 AGLDDVEQAVVIAREDRPGGKRLVGYITGTADPAEARTALAQRLPVYMVPAAVVALDAIP 924 Query: 2002 LTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXX 2061 LT NGKLD RALP PEY + + YRAPE+ TE+ LAGI+A VLGV+R Sbjct: 925 LTPNGKLDTRALPTPEYSTGE-YRAPESPTEEILAGIYAEVLGVDRVGVDESFFELGGDS 983 Query: 2062 XXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +++V A A R +F TVA+L+ Sbjct: 984 ILSLQVVARARAA-GLTCRPRDVFVEQTVARLA 1015 Score = 148 bits (374), Expect = 1e-32 Identities = 133/426 (31%), Positives = 195/426 (45%), Gaps = 31/426 (7%) Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 AQ+R L LP YMVPT +V LD P+T +GKLDR+ALPAP+Y+ A + YRAPST E+ Sbjct: 2805 AQVRERLNAWLPEYMVPTHIVALDEFPMTTSGKLDRKALPAPDYQHA-DRYRAPSTAVEE 2863 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXX 599 IL +Y QVLG+ERVGVDDSFFDLGGDS+ +M++VA A+ R +F T Sbjct: 2864 ILVGIYGQVLGLERVGVDDSFFDLGGDSLSAMRLVAAVNASLNTDLGVRTVFEAPTAAEL 2923 Query: 600 XXXXXXXXE-SHVVDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTED 653 + + G P V A + ++ + GP+ +N TV + + D Sbjct: 2924 ALRVGSEADRPEPLVAGERPAVIPLSFAQTRLWFIDQFQGPSPMYNITVALRLSGRLDAD 2983 Query: 654 DVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVP------EAGAVGARECLRTVDALTD 707 + L ++ RH +LR V T + T + +++P V AR D L + Sbjct: 2984 ALRAALADVVARHESLR-TVFATADGTPQ-QVVIPADRIGFACDVVDARGW--PEDRLRE 3039 Query: 708 DVLVEARNRLD-PAAGAMVSAVWVRETSQ--LVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 + AR D A + + ++ R + LV+ +HH+A DG S DL +A+A Sbjct: 3040 AMSAAARYTFDLSAESPLHTELFARGDDEHVLVVAVHHIAADGWSITPFARDLGVAYASR 3099 Query: 765 CTGQSIE---LPAGGTSFARWSALLAEHAKTDTVRDLA--DAWR-AVTSVPQALPPVQPD 818 C G+ + LP + W R A D W A+ +P+ L + D Sbjct: 3100 CVGRDPDWAPLPVQYADYTLWQRAHLGDVDDPGSRIAAQLDFWTDALAGLPERL-QLPTD 3158 Query: 819 TDTYVTAGQLSASLDVE---TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPI 875 A A L V+ +Q L V A ++ AF + SD + Sbjct: 3159 RPYPAVADHRGARLAVDWPAELQQQLRRVAREHNATSFMVVQAAFAALLAKVSASSDVAV 3218 Query: 876 GVDVEG 881 G + G Sbjct: 3219 GFPIAG 3224 Score = 124 bits (311), Expect = 2e-25 Identities = 64/127 (50%), Positives = 80/127 (62%) Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKT 2034 A R L LP YMVP +V L+ P+T +GKLDR+ALPAP+YQ A RYRAP T E+ Sbjct: 2805 AQVRERLNAWLPEYMVPTHIVALDEFPMTTSGKLDRKALPAPDYQHADRYRAPSTAVEEI 2864 Query: 2035 LAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 L GI+ VLG+ER AMR+ AAVN +L+ DL VRT+FEAPT A+L+ Sbjct: 2865 LVGIYGQVLGLERVGVDDSFFDLGGDSLSAMRLVAAVNASLNTDLGVRTVFEAPTAAELA 2924 Query: 2095 LHVEHDA 2101 L V +A Sbjct: 2925 LRVGSEA 2931 >tr|Q3L892|Q3L892_MYCS2 Tax_Id=246196 (mps1)SubName: Full=Non-ribosomal peptide synthetase;[Mycobacterium smegmatis] Length = 3431 Score = 2646 bits (6858), Expect = 0.0 Identities = 1353/2127 (63%), Positives = 1597/2127 (75%), Gaps = 34/2127 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P+ L + LL E E D++ GN + L++ P V+IP FA +V APDA AL Sbjct: 420 MAADPAM-PLAAVRLLAESESDRLATIGNHSALSESAPDAVSIPERFAARVAEAPDAAAL 478 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 R+ TYRELDEA+NR AH L G PG+ VA + PR+ ++++IL K GAAY+P Sbjct: 479 TFEGRTLTYRELDEAANRFAHALLARGIGPGSRVALMSPRTDRSVIAILGAFKAGAAYVP 538 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDPA P AR+ F++ DA PVA +TTA+LRSR D +DLAVID+ DPAI P+ A+S PRP Sbjct: 539 VDPAVPAARVRFILDDASPVAVVTTAELRSRFDGHDLAVIDIDDPAIASLPATAVSDPRP 598 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH N+T L++ L LP PG VW HSL FD SVWEI Sbjct: 599 DDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVLEERLPK-PG-VWPLCHSLAFDASVWEI 656 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 ALL GGRLVVVPE+V SP+D H+LL+ E+V+ L QTPSA MLSP+GLES TL V G Sbjct: 657 SNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQVTFLTQTPSAVAMLSPDGLESMTLAVVG 716 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP LVDRWA R MINAYGPTE TI S PL LFVLD W Sbjct: 717 EACPPALVDRWATNRTMINAYGPTETTICVTSSSPLEPGSVVVPIGSALPRTALFVLDPW 776 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GV GELYVAG GV GYIGR LTASRFV CPFGE G RMYRTGDLVRWG DGQ Sbjct: 777 LRPVPTGVAGELYVAGDGVTCGYIGRSGLTASRFVPCPFGEPGARMYRTGDLVRWGRDGQ 836 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 LEYLGRADEQVKIRGYRIELGE+Q+ALA LDGV+ A I REDRPGD+RLVGYITGTADP Sbjct: 837 LEYLGRADEQVKIRGYRIELGEVQSALAALDGVESAAAIMREDRPGDRRLVGYITGTADP 896 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 +R LA+ LP YMVPTA+VVL +PLT + KLD RALPAPEY +A +YRAPS P E+ Sbjct: 897 VDIRAELADRLPPYMVPTAIVVLPALPLTSSNKLDTRALPAPEYANAEKNYRAPSNPVEE 956 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXX 600 +LAD+YAQVLGVER+GVDDSFFDLGGDSILSMQVVARARAAGIQCRPRD+FVEQT Sbjct: 957 VLADIYAQVLGVERIGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDVFVEQTVARLA 1016 Query: 601 XXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ 660 E VVD+G G TPI+ WLRE G T +FNQT++ QAP GVTE DVV +LQ Sbjct: 1017 SVATVATEIGVVDDGTGSAAPTPIIHWLREAGGATDEFNQTLVVQAPTGVTEPDVVAVLQ 1076 Query: 661 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA 720 ALLDRHATLRLRV+D+ EWSLLVP+A V AR+CL VD L+DDV++ AR +L+PA Sbjct: 1077 ALLDRHATLRLRVQDSD---GEWSLLVPDAATVDARDCLSVVDTLSDDVVLAARAKLNPA 1133 Query: 721 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 780 AGAMVSA+WVR+TSQLVL+IHHLAVDGVSWRILLEDLNIAWAQH +GQ ++LPAGGTSF Sbjct: 1134 AGAMVSALWVRQTSQLVLIIHHLAVDGVSWRILLEDLNIAWAQHHSGQQVQLPAGGTSFL 1193 Query: 781 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL 840 RWS LA+HA T V ADAWR + + P ALP VQPDTDT+ +AG+ SA+LD ETTRQL Sbjct: 1194 RWSKRLADHAHTAEVTAQADAWREILAKPAALPAVQPDTDTHASAGRFSATLDPETTRQL 1253 Query: 841 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW 900 LGEVPAAF AGVQDILLVAFGLAW EFLNRS TPI VDVEGHGR++ELASD+DLSRTVGW Sbjct: 1254 LGEVPAAFHAGVQDILLVAFGLAWAEFLNRSGTPITVDVEGHGRHEELASDIDLSRTVGW 1313 Query: 901 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG 960 FTTKYPVALTV ++PW QVVAG+A LG +VK VKEQLR++P+GLTYGLLRYLN EV+LGG Sbjct: 1314 FTTKYPVALTVADVPWAQVVAGEATLGAVVKDVKEQLRAVPDGLTYGLLRYLNSEVELGG 1373 Query: 961 SDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDN 1020 ++PTIGFNYLGRLGAGAGELSEELWRI+Q VPMPL HTVELNAGT+DTD Sbjct: 1374 TEPTIGFNYLGRLGAGAGELSEELWRIEQGSLALTDVVSAVPMPLAHTVELNAGTMDTDK 1433 Query: 1021 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI 1080 GPSL+ASWTWAPS FDE++A RLS+LWFEALAGICAHV+ GGGGLTPSD+APARLTQR+I Sbjct: 1434 GPSLQASWTWAPSVFDEDKAARLSQLWFEALAGICAHVQAGGGGLTPSDIAPARLTQREI 1493 Query: 1081 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIG--------DDVYAVQLDITITGVLDQH 1132 D+L+ +++V DVLPLTP+QQGLLF + FA G DDVYAVQL IT++G LD Sbjct: 1494 DQLTTQFEVADVLPLTPLQQGLLFQAGFAEAAGAEAAGVPSDDVYAVQLGITLSGSLDPQ 1553 Query: 1133 RLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCA 1192 +LRDAV V+ RHPNLAARFVEQFGEPVQVL+ DP I W++++ D D +E+LCA Sbjct: 1554 QLRDAVQAVIRRHPNLAARFVEQFGEPVQVLSVDPEIGWQFVEFDSGDTGVDERVERLCA 1613 Query: 1193 AERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLP 1252 AERSAVC L E+P FRAALIRT+ N HRFVLT HHIVIDGWSLP+LLQEIFA YF LP Sbjct: 1614 AERSAVCKLGEQPVFRAALIRTADNLHRFVLTIHHIVIDGWSLPVLLQEIFAAYFDQSLP 1673 Query: 1253 AAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRA 1312 +AAPYRNFV WL W VL+GFETPTLVAPP GPRG+ES+R+S TTR Sbjct: 1674 SAAPYRNFVTWLGAQDRDAAQAAWGSVLEGFETPTLVAPPAQAGPRGVESFRLSEATTRT 1733 Query: 1313 LGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTV 1372 LGELARSQHTT+NTVLQAAW QLLM MTGQRDV FGTAVSGRP DLAGA+SMVGLLINTV Sbjct: 1734 LGELARSQHTTVNTVLQAAWAQLLMWMTGQRDVVFGTAVSGRPVDLAGADSMVGLLINTV 1793 Query: 1373 PIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDT 1432 P+RA TTV DLL QLQ HNDT++HEH+ALN+IH ++GH++LFDTLF+YE+YPID Sbjct: 1794 PVRATSGVATTVTDLLGQLQRDHNDTVDHEHMALNEIHRLTGHDRLFDTLFVYENYPIDA 1853 Query: 1433 SAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRL 1492 +A + VQ+LAVT+F +REYNHYPLS++A PGHE+ LRVE+DT +FD + IE L+DR +R+ Sbjct: 1854 NALLSVQDLAVTDFASREYNHYPLSMVATPGHEVVLRVEFDTEIFDAASIEALVDRLRRV 1913 Query: 1493 LEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAP 1552 L+AM DP RRLS++D++D E +LDEW NRAVLT+P + +SIP FA V R P+A Sbjct: 1914 LDAMATDPGRRLSTIDLLDPQEHDRLDEWGNRAVLTRPAPALESIPASFAESVRRVPDAV 1973 Query: 1553 AVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAY 1612 A++ S Y ELDEA+N++A+LLA GA PG+ VA+++PR+ +A+V ILA+LKTGAAY Sbjct: 1974 ALSCGDRSWTYRELDEASNRMAHLLAGRGAKPGERVAMLLPRTGEAVVTILAILKTGAAY 2033 Query: 1613 LPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTP 1672 LPIDP+ P AR+EF+L DA PVAAV++ DL +R + V+EVDDPA+ ST+L P Sbjct: 2034 LPIDPAHPDARIEFVLKDAAPVAAVSSADLCTRLIASGVPVIEVDDPAIGAEASTSLPVP 2093 Query: 1673 SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVW 1732 + DDIAY+IYTSGTTG PKGVA+TH NV Q+LDTL A+L G W+Q HSL FD SVW Sbjct: 2094 AVDDIAYIIYTSGTTGTPKGVAVTHRNVAQLLDTLGAQLEL--GQTWTQCHSLAFDYSVW 2151 Query: 1733 EIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSP---------E 1783 EIWG LL+GGRL++VP+++ SP+DLHA+LV+E V++L QTPSA + E Sbjct: 2152 EIWGPLLNGGRLLMVPDAVVRSPEDLHAMLVAEQVSMLSQTPSAFYALQTADALYPERGE 2211 Query: 1784 GLEGTALVVAGEACPTEVVDRW-----AVDRVMINAYGPTESTIYAAIS--APLSPGSDV 1836 L+ +V GEA + W + R MIN YG TE+T++A+ + Sbjct: 2212 QLKLQTVVFGGEALEPHRLSGWMHAHPGMPR-MINMYGITETTVHASFREIGEADLANST 2270 Query: 1837 VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEP 1896 PIG P+ + FVLD WLR VP GVVGELY+A LT TRFVACPFG P Sbjct: 2271 SPIGVPLEHLSFFVLDGWLRQVPVGVVGELYVAGEGLACGYISRSDLTSTRFVACPFGAP 2330 Query: 1897 GARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARE 1956 GARMYRTGDLVRWG DGQLQY+GRADEQVKIRGYRIELGE+ AAL +DGV+QA VIARE Sbjct: 2331 GARMYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVIARE 2390 Query: 1957 DRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAP 2016 DRPGDKRLVGY+TG DP AR+ L R+PAYMVPAA+V +E+LPLTVNGKL+ RALPAP Sbjct: 2391 DRPGDKRLVGYVTGAVDPVKARAALAERIPAYMVPAAIVVMESLPLTVNGKLNTRALPAP 2450 Query: 2017 EYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALD 2076 EYQ A +YRAP E+ L GI+A VLGVER +M+V A A Sbjct: 2451 EYQDADQYRAPANAVEELLTGIYAQVLGVERVGVDDSFFDLGGDSISSMQVVARARAA-G 2509 Query: 2077 ADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 R +F TV++L+ V GE Sbjct: 2510 LVCRPRDIFVEQTVSRLAQVVTLADGE 2536 Score = 1865 bits (4830), Expect = 0.0 Identities = 955/1521 (62%), Positives = 1143/1521 (75%), Gaps = 33/1521 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M +P R L + DLLD EHD+++ WGNRAVLT P P +IPA FAE V R PDAVAL Sbjct: 1917 MATDPGRR-LSTIDLLDPQEHDRLDEWGNRAVLTRPAPALESIPASFAESVRRVPDAVAL 1975 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 GDRSWTYRELDEASNR+AH+LA GAKPG VA L+PR+GEA+++IL++LKTGAAYLP Sbjct: 1976 SCGDRSWTYRELDEASNRMAHLLAGRGAKPGERVAMLLPRTGEAVVTILAILKTGAAYLP 2035 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAHPDARI F++ DA PVAA+++ADL +RL + VI++ DPAI S +L P Sbjct: 2036 IDPAHPDARIEFVLKDAAPVAAVSSADLCTRLIASGVPVIEVDDPAIGAEASTSLPVPAV 2095 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH NV QL+ L A L G Q W+Q HSL FD SVWEI Sbjct: 2096 DDIAYIIYTSGTTGTPKGVAVTHRNVAQLLDTLGAQLELG--QTWTQCHSLAFDYSVWEI 2153 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPEG---L 291 WG LL+GGRL++VP++V SP+DLH +L+ E+VS+L QTPSA A L PE L Sbjct: 2154 WGPLLNGGRLLMVPDAVVRSPEDLHAMLVAEQVSMLSQTPSAFYALQTADALYPERGEQL 2213 Query: 292 ESTTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSE--PLXXXXXXXXX 345 + T++ GEA + W PG MIN YG TE T++A+ E Sbjct: 2214 KLQTVVFGGEALEPHRLSGWMHAHPGMPRMINMYGITETTVHASFREIGEADLANSTSPI 2273 Query: 346 XXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 FVLD WLR P GVVGELYVAG G+A GYI R DLT++RFVACPFG G R Sbjct: 2274 GVPLEHLSFFVLDGWLRQVPVGVVGELYVAGEGLACGYISRSDLTSTRFVACPFGAPGAR 2333 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLVRWG+DGQL+Y+GRADEQVKIRGYRIELGE+ AAL LDGV+QA VIAREDRP Sbjct: 2334 MYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVIAREDRP 2393 Query: 466 GDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 GDKRLVGY+TG DP + R ALAE +PAYMVP A+VV++++PLTVNGKL+ RALPAPEY+ Sbjct: 2394 GDKRLVGYVTGAVDPVKARAALAERIPAYMVPAAIVVMESLPLTVNGKLNTRALPAPEYQ 2453 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQC 585 A + YRAP+ E++L +YAQVLGVERVGVDDSFFDLGGDSI SMQVVARARAAG+ C Sbjct: 2454 DA-DQYRAPANAVEELLTGIYAQVLGVERVGVDDSFFDLGGDSISSMQVVARARAAGLVC 2512 Query: 586 RPRDIFVEQTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVIT 644 RPRDIFVEQT ES V D GVGPVVATPIMRWL +DGP +FNQTV+ Sbjct: 2513 RPRDIFVEQTVSRLAQVVTLADGESGVADTGVGPVVATPIMRWLYSLDGPIDEFNQTVVL 2572 Query: 645 QAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA 704 Q PA VTE DV+ +LQA+LD HA LRLRV D + L VPE G+V A +CL TV Sbjct: 2573 QVPAEVTEADVIAVLQAVLDHHAMLRLRVADAENG----DLTVPEPGSVDACDCLCTVGE 2628 Query: 705 LTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 LT D L R +L+PA G+M++A WV ET QL LMIHHLAVD VSWRILLEDLNIAWAQH Sbjct: 2629 LTADTLAAVRAQLNPATGSMLTAAWVPETRQLALMIHHLAVDAVSWRILLEDLNIAWAQH 2688 Query: 765 CTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVT 824 +GQ + LP GTSF RWS LL +HA+T V AD WR V + P ALP QPDTD Y Sbjct: 2689 RSGQPVVLPTPGTSFGRWSRLLDQHARTADVLATADVWRTVAAAPAALPAPQPDTDVYAN 2748 Query: 825 AGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGR 884 AGQLSASLDVETT QLLG+VPAAF AGVQDILL+AFGLAW+E+L IG+DVEGHGR Sbjct: 2749 AGQLSASLDVETTGQLLGDVPAAFHAGVQDILLIAFGLAWSEYLGSEQGSIGIDVEGHGR 2808 Query: 885 YDELASDVDLSRTVGWFTTKYPVALTVE----NLPWEQVVAGDAALGGIVKAVKEQLRSL 940 +EL D DLSRTVGWFT+KYPVAL + + WEQVV GDAALG ++K KEQLRS+ Sbjct: 2809 TEELFGDADLSRTVGWFTSKYPVALDFDRNTGGISWEQVVNGDAALGAVIKKAKEQLRSV 2868 Query: 941 PEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXX 1000 P+GLTYGLLRYLNP+V+L DPTIGFNYLGRLGAGA +LS++LWR+D Sbjct: 2869 PDGLTYGLLRYLNPDVELDNPDPTIGFNYLGRLGAGAADLSDDLWRLDPDAVSLTAAGGR 2928 Query: 1001 VPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRG 1060 V PL HTVELNAGT+DT+ GP L+A+WTWAPSA DEEQ ++S+LW +ALAGICAHVR Sbjct: 2929 VNTPLGHTVELNAGTMDTEAGPQLQATWTWAPSALDEEQIQKVSKLWSDALAGICAHVRS 2988 Query: 1061 GGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQ 1120 GGGGLTPSDVAPARL+Q+QID+L+ ++D+ DVLPLTP+Q GLLFH+ ++ +D+YAVQ Sbjct: 2989 GGGGLTPSDVAPARLSQQQIDDLTAQFDMVDVLPLTPLQHGLLFHTGLSQD-SEDLYAVQ 3047 Query: 1121 LDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRG-D 1179 LDI+++G LD R+RDAV TV+ R PN+ A F E FGEPVQ+L A+P +AW+Y+DL G Sbjct: 3048 LDISVSGRLDVERMRDAVQTVITRRPNVVAHFYEDFGEPVQILPANPELAWQYVDLSGRS 3107 Query: 1180 DLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILL 1239 D+ D +I Q+ AAER+AVC L ++P FRAA++RT +RFVLT HHIV+DGWS PILL Sbjct: 3108 DI--DAQIAQISAAERAAVCRLGDQPPFRAAVLRTGEETYRFVLTNHHIVLDGWSKPILL 3165 Query: 1240 QEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVP-GPR 1298 QEIF YFG RLPA PYR FV+WL WR V GFETPTLV PG+ G R Sbjct: 3166 QEIFVSYFGQRLPAPVPYRRFVSWLAEQDNDAARAAWRGVFSGFETPTLVGTPGLALGRR 3225 Query: 1299 GIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADL 1358 +ES++VSAETT+ALGELARS HTT++TVLQ AW Q+LM +TGQ DVAFGTAVSGRP D+ Sbjct: 3226 AVESFQVSAETTQALGELARSCHTTVSTVLQGAWAQVLMWLTGQPDVAFGTAVSGRPTDV 3285 Query: 1359 AGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQL 1418 GA+SMVGLLINTVP+RA ++ +TTV L+ QLQ + DTL+H+HLALN+IH +GH+QL Sbjct: 3286 PGADSMVGLLINTVPVRATITPETTVASLMNQLQGAYTDTLDHQHLALNEIHRATGHDQL 3345 Query: 1419 FDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFD 1478 FDT+F+YE+YPIDT+A +GVQEL++T+F NREYNHYPLSV A+PGHELGLRVEYDT+VFD Sbjct: 3346 FDTVFVYENYPIDTAALLGVQELSITDFTNREYNHYPLSVQAVPGHELGLRVEYDTNVFD 3405 Query: 1479 VSEIETLIDRFQRLLEAMIDD 1499 I+ L++R QR+L AM D Sbjct: 3406 RQRIKRLVNRLQRVLVAMTAD 3426 Score = 696 bits (1795), Expect = 0.0 Identities = 426/988 (43%), Positives = 552/988 (55%), Gaps = 27/988 (2%) Query: 1125 ITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD 1184 I GV+D L+ A+ + A F E G+ Q + D+R D P+ Sbjct: 38 IDGVVDHGLLQQAIRQALQEAEPARATFFEADGQVFQKPLDYSELEVPLYDVRDAD-DPE 96 Query: 1185 HEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFA 1244 + ++ A + L R + AL +T Q HHI +DG + ++ + I Sbjct: 97 AKAREMAAEIQHTPLPLTGR-LVKFALFQTRDEQFYLFGLGHHISVDGLGMALVSRRIST 155 Query: 1245 GYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG-------VPGP 1297 Y P F + + D + PP P P Sbjct: 156 IYTSLVTGKPVPEAYFGSLRDLVECEMSYESSADYQDDLAYWSENLPPDTGLDQGLAPTP 215 Query: 1298 RGIESYRVSAET------TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRD-VAFGTA 1350 G +Y SA + EL+++ +V AA L + D VA Sbjct: 216 HGKNAYTPSASVPMDPAIVGRIKELSKTLRIRRYSVTTAACALLAQSWSSTGDQVALDFP 275 Query: 1351 VSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHL---ALN 1407 VS R + ++++ +L P+ TVG+ + + + L+H+ L Sbjct: 276 VSRRVS--PESKTLPAMLAGVAPLVLDAPPQLTVGEFCKHVDIRIRELLQHQRFPVHRLG 333 Query: 1408 DIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELG 1467 D + G Q + L + T F G E + N+ H+ L + G EL Sbjct: 334 DGGALRGPRQASNRLAVNFIPSRLTLDFAGA-EATASYTNHGPMGHFGLFFIG-AGEELF 391 Query: 1468 LRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 L F E+ L +R ++ AM DPA L+++ ++ + E +L N + L Sbjct: 392 LSTAGAGQPFANFEVPELAERLGAIVAAMAADPAMPLAAVRLLAESESDRLATIGNHSAL 451 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 ++ SIPE FA +V P+A A+TFEG +L Y ELDEAAN+ A+ L G PG Sbjct: 452 SESAPDAVSIPERFAARVAEAPDAAALTFEGRTLTYRELDEAANRFAHALLARGIGPGSR 511 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VALM PR+ +++AIL K GAAY+P+DP+VPAAR+ F+L DA PVA VTT +LRSRFD Sbjct: 512 VALMSPRTDRSVIAILGAFKAGAAYVPVDPAVPAARVRFILDDASPVAVVTTAELRSRFD 571 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 G DL V+++DDPA+ P+T + P PDDIAY+IYTSGTTG PKGVA+TH N+T ++ L Sbjct: 572 GHDLAVIDIDDPAIASLPATAVSDPRPDDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVL 631 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 LP PG VW HSL FD SVWEI ALL GGRLV+VPE++AGSP+D H LLV+E V Sbjct: 632 EERLPK-PG-VWPLCHSLAFDASVWEISNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQV 689 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAIS 1827 L QTPSAV M+SP+GLE L V GEACP +VDRWA +R MINAYGPTE+TI S Sbjct: 690 TFLTQTPSAVAMLSPDGLESMTLAVVGEACPPALVDRWATNRTMINAYGPTETTICVTSS 749 Query: 1828 APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTR 1887 +PL PGS VVPIGS +P+ A FVLD WLRPVP GV GELY+A LT +R Sbjct: 750 SPLEPGSVVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVTCGYIGRSGLTASR 809 Query: 1888 FVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGV 1947 FV CPFGEPGARMYRTGDLVRWG DGQL+YLGRADEQVKIRGYRIELGE+Q+AL+ +DGV Sbjct: 810 FVPCPFGEPGARMYRTGDLVRWGRDGQLEYLGRADEQVKIRGYRIELGEVQSALAALDGV 869 Query: 1948 DQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGK 2007 + A I REDRPGD+RLVGYITGTADP R+EL +RLP YMVP A+V L LPLT + K Sbjct: 870 ESAAAIMREDRPGDRRLVGYITGTADPVDIRAELADRLPPYMVPTAIVVLPALPLTSSNK 929 Query: 2008 LDRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMR 2066 LD RALPAPEY +A++ YRAP E+ LA I+A VLGVER +M+ Sbjct: 930 LDTRALPAPEYANAEKNYRAPSNPVEEVLADIYAQVLGVERIGVDDSFFDLGGDSILSMQ 989 Query: 2067 VTAAVNTALDADLSVRTLFEAPTVAKLS 2094 V A A R +F TVA+L+ Sbjct: 990 VVARARAA-GIQCRPRDVFVEQTVARLA 1016 >tr|D5P2M4|D5P2M4_9MYCO Tax_Id=525368 SubName: Full=Linear gramicidin synthetase subunit D; EC=1.-.-.-;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 3418 Score = 2597 bits (6732), Expect = 0.0 Identities = 1337/2112 (63%), Positives = 1596/2112 (75%), Gaps = 32/2112 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P R L S DLL DE QI+ W NRA LT+P P PV+IP FAE V R+PDA A+ Sbjct: 420 MTADPE-RWLSSIDLLAADEPAQIDEWSNRAALTEPVPAPVSIPVAFAEHVHRSPDAPAV 478 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 +S TY ELDEASNRLAH+LA HG PG VA + PR +AI+++L+VLKTGAAY+P Sbjct: 479 TCSAKSLTYAELDEASNRLAHLLAGHGVGPGGCVAVMFPRCADAIVAMLAVLKTGAAYVP 538 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAH AR+ F++SDA P A +TTADLRSRLD DL V+D+ DPA+ +PS AL GP P Sbjct: 539 IDPAHSAARMEFVLSDAAPSAVITTADLRSRLDGRDLLVVDVHDPAVGEQPSTALPGPAP 598 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +++AY+ YTSGTTG PK VA+ H NVT L+ +L A LP G QVW+Q HS FD SVWEI Sbjct: 599 ENIAYIIYTSGTTGTPKGVAIPHLNVTWLIESLDAGLPKG--QVWTQCHSSAFDFSVWEI 656 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GA+L G RL+VVPESV SSP++LH+LL+ EKVSVL QTPS+ ML +GLEST L+VAG Sbjct: 657 FGAVLRGRRLLVVPESVASSPEELHDLLVAEKVSVLTQTPSSVAMLPADGLESTALVVAG 716 Query: 301 EACPTELVDRWA-PGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 EACPT++VDRWA PGRVM++AYGPTE T+ A++S+PL +FVLDK Sbjct: 717 EACPTDVVDRWAAPGRVMLDAYGPTETTVCASISKPLIPGSGVVPIGSPIAGAAMFVLDK 776 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WL+P P GVVGELY+AG GV GY+ R LTASRFVA PFG G RMYRTGDLV WG DG Sbjct: 777 WLQPVPAGVVGELYLAGRGVGIGYVRRSGLTASRFVANPFGGPGARMYRTGDLVCWGEDG 836 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+Y GR+DEQVKIRGYRIELGEIQ+ L LDGVDQA V+AREDRPGDKRLVGYITGTAD Sbjct: 837 QLQYFGRSDEQVKIRGYRIELGEIQSVLKGLDGVDQAAVVAREDRPGDKRLVGYITGTAD 896 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA +R ALA+ LP YMVP AVVVL+ +PLT NGKLD+RALPAPEY +A +YRAP P E Sbjct: 897 PAAIRAALADRLPPYMVPAAVVVLEALPLTGNGKLDKRALPAPEYATA--EYRAPEDPVE 954 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 +ILAD+YAQVLG+ERVGVD SFFDLGGDSILSMQVVARARAAGI RPRD+FVEQ+ Sbjct: 955 EILADIYAQVLGLERVGVDASFFDLGGDSILSMQVVARARAAGILFRPRDVFVEQSVARL 1014 Query: 600 XXXXXXXXESH--VVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVV 657 + D+GVGPVVATPIMRWL+ ++GP QFNQT++ QAPAG TE DVV Sbjct: 1015 ARVAEVAADGAGGAGDDGVGPVVATPIMRWLQSIEGPIEQFNQTMVVQAPAGATEADVVA 1074 Query: 658 ILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRL 717 +LQALLDRHA LRLR +D + WSL VPE GAV AR C+ V++L+ + L EAR+RL Sbjct: 1075 VLQALLDRHAALRLRADD--DGAGGWSLQVPEPGAVDARGCVHAVESLSGEALAEARSRL 1132 Query: 718 DPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGT 777 +PAAG +VSA W + T QL L+IHHLAVDGVSWRILLED NIAWAQH GQ + L A GT Sbjct: 1133 NPAAGVLVSAAWAQSTGQLALIIHHLAVDGVSWRILLEDFNIAWAQHHNGQPVALLAPGT 1192 Query: 778 SFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETT 837 SFARWS LL E+A+ V AD WR V + P ALP VQPD DTYV+AGQLSASLDVETT Sbjct: 1193 SFARWSTLLQEYAQRPDVVARADEWRQVAATPAALPAVQPDADTYVSAGQLSASLDVETT 1252 Query: 838 RQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRT 897 R LLGEVPAAF AGV DILL+AFGLA+ EFL PIG+DVEGHGR +EL VDLSRT Sbjct: 1253 RLLLGEVPAAFHAGVGDILLIAFGLAFAEFLGTGAAPIGIDVEGHGRQEELFPRVDLSRT 1312 Query: 898 VGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVD 957 VGWFTTKYPVALT L W QVVAGDAALG ++KA KEQLR+LP+GLTYGLLRYLNP+VD Sbjct: 1313 VGWFTTKYPVALTPGRLSWSQVVAGDAALGPVIKAAKEQLRALPDGLTYGLLRYLNPDVD 1372 Query: 958 LGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTID 1017 L GSDP IGFNYLGRLGAGA +LS+ELWR+ V MPL HTVELNAGT+D Sbjct: 1373 LDGSDPVIGFNYLGRLGAGA-DLSDELWRVSHDSLAVAAVASAVAMPLAHTVELNAGTLD 1431 Query: 1018 TDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQ 1077 T+ GP L+A+W+WAPSA D ++ RLS+LWFEALAGICAHV+ GGGGLTPSD+APA L+Q Sbjct: 1432 TEAGPHLQANWSWAPSALDHDRVDRLSQLWFEALAGICAHVKAGGGGLTPSDIAPAHLSQ 1491 Query: 1078 RQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDA 1137 +QID L ++ V DVLPLTPVQQGLLFH+ FA+ + DD+YAVQL IT++G LD RLR+A Sbjct: 1492 QQIDALCRQGGVADVLPLTPVQQGLLFHTAFAQDM-DDLYAVQLGITVSGALDAARLREA 1550 Query: 1138 VHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSA 1197 VHT V RHPNL ARF E FGEPVQV+ ADP +AWRY++L G D+ D ++++LCA ER+A Sbjct: 1551 VHTAVKRHPNLVARFSEDFGEPVQVIPADPQMAWRYVELDGGDV--DGQVDRLCADERAA 1608 Query: 1198 VCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPY 1257 VCDL +P+FRAALIRT+ ++HRFVLT HHIV+DGWSLPILLQE+FA Y+G RLPAA Y Sbjct: 1609 VCDLAGKPSFRAALIRTAPDRHRFVLTIHHIVVDGWSLPILLQEVFASYYGERLPAAPSY 1668 Query: 1258 RNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGELA 1317 R+FV WL W + L GFETPTLV P G G RG+ ++ V A+TT+ALGELA Sbjct: 1669 RSFVTWLTNQDRAAAQAAWAQALAGFETPTLVGPLGQIGRRGVAAFHVPADTTKALGELA 1728 Query: 1318 RSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAK 1377 RS TT++TVLQ AWTQLL +TGQ DVAFGTAVSGRP +LAGA++MVGLLINTVP+RA+ Sbjct: 1729 RSCRTTLSTVLQGAWTQLLTWLTGQHDVAFGTAVSGRPTELAGADAMVGLLINTVPVRAR 1788 Query: 1378 VSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMG 1437 ++A TTV DLL QLQ HNDT+++EHLAL DIH +GH+QLFDTLFLYE+YPID A +G Sbjct: 1789 ITATTTVADLLEQLQRLHNDTVDYEHLALPDIHRATGHDQLFDTLFLYENYPIDAGALLG 1848 Query: 1438 VQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMI 1497 V ELAVT+F++REYNHYPLSV+ PGHEL +RVE+DT VFD + ++TLIDR Q+++ AM Sbjct: 1849 VHELAVTDFSSREYNHYPLSVVVSPGHELSMRVEFDTEVFDRAAVDTLIDRLQQVMVAMT 1908 Query: 1498 DDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFE 1557 DPARRLSS+D++D E +LD+W NR VL + P SI E+FA Q R PEA A+T Sbjct: 1909 ADPARRLSSIDLLDAAEHDRLDDWGNRGVLAESAPKPVSIAELFAAQAARAPEAVAITDG 1968 Query: 1558 GESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDP 1617 S YGE++E+AN+LA+LL GA PG+ VA++ PR+A+A+VAILAVLKTGAAYLP+DP Sbjct: 1969 DRSWTYGEVEESANRLAHLLVSRGAGPGERVAVLFPRTAEAVVAILAVLKTGAAYLPVDP 2028 Query: 1618 SVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDI 1677 +VPAAR+EF+LGDA P+AAVTT D+RSR DG DL V+E DDPAV P L PSP++I Sbjct: 2029 TVPAARIEFVLGDAAPIAAVTTADVRSRLDGQDLDVIEFDDPAVANQPGDGLPAPSPENI 2088 Query: 1678 AYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGA 1737 AY+IYTSGTTG PKGVA+ H NVTQ+L++L A+L G VW+Q HSL FD SVWEI+G+ Sbjct: 2089 AYIIYTSGTTGTPKGVAVPHRNVTQLLESLDAQLAL--GQVWTQCHSLAFDFSVWEIFGS 2146 Query: 1738 LLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA------VRMMSPE---GLEGT 1788 LL+GGRLVIVP+++ SP++LHA+LV E V+VL QTPSA + PE L+ Sbjct: 2147 LLYGGRLVIVPDNVVRSPEELHAMLVREQVSVLSQTPSAFYALQTADSLQPELGQQLKLQ 2206 Query: 1789 ALVVAGEACPTEVVDRWAVDRV----MINAYGPTESTIYAAISAPLSPGSD--VVPIGSP 1842 +V GEA + +W + +IN YG TE+T++A+ + D PIG P Sbjct: 2207 TVVFGGEALEPHRLGKWLHNHPGLPRLINMYGITETTVHASFREIVDGDVDNSASPIGVP 2266 Query: 1843 VPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYR 1902 + FVLD WLRPVP GVVGELY+A L+ TRFVACPFG GARMYR Sbjct: 2267 LAHLGFFVLDGWLRPVPEGVVGELYVAGRGLAYGYVGRSGLSATRFVACPFGGSGARMYR 2326 Query: 1903 TGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDK 1962 TGDLVRWG DGQLQY+GRADEQVKIRGYRIELGE+ AAL+ +DGV++A VIAREDRPGDK Sbjct: 2327 TGDLVRWGADGQLQYMGRADEQVKIRGYRIELGEVHAALAALDGVNEAAVIAREDRPGDK 2386 Query: 1963 RLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQ 2022 RLVGY+TGTADPAA R++L RLP YMVP AVV LE LPLTVNGKLD RALPAPEY A Sbjct: 2387 RLVGYVTGTADPAAIRNQLGERLPTYMVPTAVVVLEALPLTVNGKLDTRALPAPEYSDAD 2446 Query: 2023 RYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVR 2082 YRAP T E+ LAGI+A VLGVER +M+V A A R Sbjct: 2447 HYRAPSTAVEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GVVCRPR 2505 Query: 2083 TLFEAPTVAKLS 2094 +F TV++L+ Sbjct: 2506 DIFVEQTVSRLA 2517 Score = 1947 bits (5045), Expect = 0.0 Identities = 986/1516 (65%), Positives = 1165/1516 (76%), Gaps = 26/1516 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P+ R L S DLLD EHD+++ WGNR VL + P PV+I LFA Q RAP+AVA+ Sbjct: 1907 MTADPARR-LSSIDLLDAAEHDRLDDWGNRGVLAESAPKPVSIAELFAAQAARAPEAVAI 1965 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 GDRSWTY E++E++NRLAH+L GA PG VA L PR+ EA+++IL+VLKTGAAYLP Sbjct: 1966 TDGDRSWTYGEVEESANRLAHLLVSRGAGPGERVAVLFPRTAEAVVAILAVLKTGAAYLP 2025 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDP P ARI F++ DA P+AA+TTAD+RSRLD DL VI+ DPA+ +P D L P P Sbjct: 2026 VDPTVPAARIEFVLGDAAPIAAVTTADVRSRLDGQDLDVIEFDDPAVANQPGDGLPAPSP 2085 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +++AY+ YTSGTTG PK VAV H NVTQL+ +L A L G QVW+Q HSL FD SVWEI Sbjct: 2086 ENIAYIIYTSGTTGTPKGVAVPHRNVTQLLESLDAQLALG--QVWTQCHSLAFDFSVWEI 2143 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPE---GL 291 +G+LL+GGRLV+VP++V SP++LH +L+ E+VSVL QTPSA A L PE L Sbjct: 2144 FGSLLYGGRLVIVPDNVVRSPEELHAMLVREQVSVLSQTPSAFYALQTADSLQPELGQQL 2203 Query: 292 ESTTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSEPLXXXXXXXXXXX 347 + T++ GEA + +W PG +IN YG TE T++A+ E + Sbjct: 2204 KLQTVVFGGEALEPHRLGKWLHNHPGLPRLINMYGITETTVHASFREIVDGDVDNSASPI 2263 Query: 348 XXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 L FVLD WLRP PEGVVGELYVAG G+A GY+GR L+A+RFVACPFG +G R Sbjct: 2264 GVPLAHLGFFVLDGWLRPVPEGVVGELYVAGRGLAYGYVGRSGLSATRFVACPFGGSGAR 2323 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLVRWG+DGQL+Y+GRADEQVKIRGYRIELGE+ AALA LDGV++A VIAREDRP Sbjct: 2324 MYRTGDLVRWGADGQLQYMGRADEQVKIRGYRIELGEVHAALAALDGVNEAAVIAREDRP 2383 Query: 466 GDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 GDKRLVGY+TGTADPA +R L E LP YMVPTAVVVL+ +PLTVNGKLD RALPAPEY Sbjct: 2384 GDKRLVGYVTGTADPAAIRNQLGERLPTYMVPTAVVVLEALPLTVNGKLDTRALPAPEY- 2442 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQC 585 S A+ YRAPST E+ILA +YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ C Sbjct: 2443 SDADHYRAPSTAVEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVVC 2502 Query: 586 RPRDIFVEQTXXXXXXXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQ 645 RPRDIFVEQT + VVDEG+GPVVATPIMRWL VDGP QFNQT++ Q Sbjct: 2503 RPRDIFVEQTVSRLARVAGLATDDDVVDEGIGPVVATPIMRWLHSVDGPVEQFNQTMVVQ 2562 Query: 646 APAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDAL 705 APAG E DVV +LQALLDRHA LRLRV+D + W+L VPE G V A C+ TV+ L Sbjct: 2563 APAGANETDVVAVLQALLDRHAMLRLRVDD--DGAGGWALRVPETGVVDAAGCVHTVETL 2620 Query: 706 TDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHC 765 +D L A ++L+PA+GAM+ AVWV T QL L+IHHLAVDGVSWRILLED NIAWAQH Sbjct: 2621 SDAALAAAVSQLNPASGAMLRAVWVPSTGQLALIIHHLAVDGVSWRILLEDFNIAWAQHH 2680 Query: 766 TGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTA 825 +GQ + LP GG SFARWS+LLAEHA+ V D A+AWR ++S P LP V PD DTYV+A Sbjct: 2681 SGQPVALPVGGMSFARWSSLLAEHARRPEVVDTAEAWRQISSTPAPLPAVSPDIDTYVSA 2740 Query: 826 GQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRY 885 GQLS +LD +TTR LLGEVPAAF AGVQDILL+AFGLAW +F+ + PIG+DVEGHGR+ Sbjct: 2741 GQLSVALDADTTRMLLGEVPAAFHAGVQDILLIAFGLAWAQFVG-TGAPIGIDVEGHGRH 2799 Query: 886 DELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLT 945 +EL VDLSRTVGWFTTKYPVAL V L W VV G+A LG +VK KEQLR+LP+ LT Sbjct: 2800 EELGPHVDLSRTVGWFTTKYPVALQVGGLSWGHVVTGEAELGALVKDAKEQLRALPDTLT 2859 Query: 946 YGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPL 1005 YGLLRYLN +VDL SDP IGFNYLGRLG GAG+LS ELWR+DQ VP+PL Sbjct: 2860 YGLLRYLNGDVDLDASDPVIGFNYLGRLG-GAGDLSSELWRLDQDSLASAGAATAVPLPL 2918 Query: 1006 MHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGL 1065 HTVELNAGT+DT GP L+A+WTWA SA DE Q RLS LWF+AL+GIC+HVR GGGGL Sbjct: 2919 PHTVELNAGTLDTATGPLLQANWTWARSALDEGQVARLSELWFDALSGICSHVRSGGGGL 2978 Query: 1066 TPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITI 1125 TPSD+APARLTQR IDEL QRY + DVLPLTP+QQGLLFH+ A G DD+YAVQLDI++ Sbjct: 2979 TPSDLAPARLTQRDIDELCQRYPIADVLPLTPLQQGLLFHTGTAHG-SDDLYAVQLDISV 3037 Query: 1126 TGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDH 1185 +G LD HRLRDAVHT++ RHPN+ A FVE FGEPVQVL+A+P ++W Y++L DD P+ Sbjct: 3038 SGALDPHRLRDAVHTMLKRHPNVVAHFVEDFGEPVQVLSAEPPLSWHYVELDADDAEPEE 3097 Query: 1186 EIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAG 1245 +I+QLCA ER+AVCDL ERP FRAALIRT+ N+HRFVLT HHIV+DGWS PILLQEIFA Sbjct: 3098 QIQQLCAGERAAVCDLAERPPFRAALIRTADNRHRFVLTNHHIVLDGWSKPILLQEIFAA 3157 Query: 1246 YFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVP--GPRGIESY 1303 Y+G +LPA PYR FV WL WR VL GF+TPTLV P G GPR + S+ Sbjct: 3158 YYGVQLPAPVPYRKFVAWLAAQDRGAAQAAWRRVLAGFDTPTLVGPAGRMSLGPRSVSSF 3217 Query: 1304 RVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAES 1363 ++SAETTRALGELARS TT++TVLQAAW QLLM +TGQ DV FGTAVSGRP +LAG++ Sbjct: 3218 QMSAETTRALGELARSCRTTVSTVLQAAWAQLLMWLTGQHDVTFGTAVSGRPTELAGSDQ 3277 Query: 1364 MVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLF 1423 MVGLLINTVP+RA + A+TT+ DLL QLQS +NDTLEH+HLALNDIH V+GH+QLFDT+F Sbjct: 3278 MVGLLINTVPVRATIDAETTIADLLNQLQSAYNDTLEHQHLALNDIHRVTGHDQLFDTMF 3337 Query: 1424 LYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIE 1483 +YE+YPIDT+A ELA+ F NRE+NHYPLSV A+PGHELGLRVE+DT VFD IE Sbjct: 3338 VYENYPIDTAALSAADELAIDGFTNREFNHYPLSVQAVPGHELGLRVEFDTEVFDQGRIE 3397 Query: 1484 TLIDRFQRLLEAMIDD 1499 L++RF+R+LEAM D Sbjct: 3398 RLVERFRRVLEAMTAD 3413 Score = 741 bits (1912), Expect = 0.0 Identities = 456/988 (46%), Positives = 582/988 (58%), Gaps = 28/988 (2%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 I I G +D+ L A+ VA F E G+ VQ P + + DL Sbjct: 40 IRIDGPVDRDALGRALTQTVAEAEAARVSFFEVDGQVVQQPIDYPDVELAFHDLTS---L 96 Query: 1183 PDHEIEQLCAAERSAVCDL-LERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQE 1241 PD E A + L F+ L +T ++ HHI IDG + ++ + Sbjct: 97 PDPVQEARAMASSIQRTPMALNGQLFQFVLFQTGVDEFYLFGCCHHIAIDGLGMALVARR 156 Query: 1242 IFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVP------ 1295 + Y P F + + D + PP Sbjct: 157 VATIYSAMMAGKPIPDAYFGSAQDLVDLESEYEASPDYQDDKAYWSNNLPPETAWVDRPA 216 Query: 1296 -GPRGIESYRVSAET------TRALGELARSQHTTINTVLQAAWTQLLMRMTGQR-DVAF 1347 G G + Y SA T + EL++ +V AA L+ +G +VA Sbjct: 217 DGTSGKDHYSPSASVQLDPSVTTRIKELSKKLGIRRFSVTTAACALLVRAWSGSGYEVAL 276 Query: 1348 GTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALN 1407 VS R ++++ G+ VP+ S +V D + + + L+H+ ++ Sbjct: 277 DFPVSRRVRQ--ESKTLPGMFAGVVPLVLNTSPTASVADFCKHVDIKIRELLQHQRFPVH 334 Query: 1408 DIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELG 1467 + G Q + + + P+ + + T N+ H+ L + G +L Sbjct: 335 TLES-DGLRQAANRVGI-NFIPMRLTLDLAGSPATATYTNHGPVGHFSLFFLGA-GDQLF 391 Query: 1468 LRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 L F + L R Q++LE M DP R LSS+D++ DE Q+DEW+NRA L Sbjct: 392 LSTAGPGQPFADFGVADLAARMQQVLEEMTADPERWLSSIDLLAADEPAQIDEWSNRAAL 451 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 T+PV +P SIP FA V R P+APAVT +SL Y ELDEA+N+LA+LLA +G PG Sbjct: 452 TEPVPAPVSIPVAFAEHVHRSPDAPAVTCSAKSLTYAELDEASNRLAHLLAGHGVGPGGC 511 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VA+M PR ADAIVA+LAVLKTGAAY+PIDP+ AAR+EF+L DA P A +TT DLRSR D Sbjct: 512 VAVMFPRCADAIVAMLAVLKTGAAYVPIDPAHSAARMEFVLSDAAPSAVITTADLRSRLD 571 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 G DL VV+V DPAV PST L P+P++IAY+IYTSGTTG PKGVAI H NVT ++++L Sbjct: 572 GRDLLVVDVHDPAVGEQPSTALPGPAPENIAYIIYTSGTTGTPKGVAIPHLNVTWLIESL 631 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 A LP G VW+Q HS FD SVWEI+GA+L G RL++VPES+A SP++LH LLV+E V Sbjct: 632 DAGLP--KGQVWTQCHSSAFDFSVWEIFGAVLRGRRLLVVPESVASSPEELHDLLVAEKV 689 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAV-DRVMINAYGPTESTIYAAI 1826 +VL QTPS+V M+ +GLE TALVVAGEACPT+VVDRWA RVM++AYGPTE+T+ A+I Sbjct: 690 SVLTQTPSSVAMLPADGLESTALVVAGEACPTDVVDRWAAPGRVMLDAYGPTETTVCASI 749 Query: 1827 SAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGT 1886 S PL PGS VVPIGSP+ A FVLD+WL+PVP GVVGELYLA LT + Sbjct: 750 SKPLIPGSGVVPIGSPIAGAAMFVLDKWLQPVPAGVVGELYLAGRGVGIGYVRRSGLTAS 809 Query: 1887 RFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDG 1946 RFVA PFG PGARMYRTGDLV WG+DGQLQY GR+DEQVKIRGYRIELGEIQ+ L +DG Sbjct: 810 RFVANPFGGPGARMYRTGDLVCWGEDGQLQYFGRSDEQVKIRGYRIELGEIQSVLKGLDG 869 Query: 1947 VDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNG 2006 VDQA V+AREDRPGDKRLVGYITGTADPAA R+ L +RLP YMVPAAVV LE LPLT NG Sbjct: 870 VDQAAVVAREDRPGDKRLVGYITGTADPAAIRAALADRLPPYMVPAAVVVLEALPLTGNG 929 Query: 2007 KLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMR 2066 KLD+RALPAPEY +A+ YRAPE E+ LA I+A VLG+ER +M+ Sbjct: 930 KLDKRALPAPEYATAE-YRAPEDPVEEILADIYAQVLGLERVGVDASFFDLGGDSILSMQ 988 Query: 2067 VTAAVNTALDADLSVRTLFEAPTVAKLS 2094 V A A R +F +VA+L+ Sbjct: 989 VVARARAA-GILFRPRDVFVEQSVARLA 1015 >tr|Q740V0|Q740V0_MYCPA Tax_Id=1770 (pstA)SubName: Full=PstA;[Mycobacterium paratuberculosis] Length = 4027 Score = 2580 bits (6688), Expect = 0.0 Identities = 1323/2119 (62%), Positives = 1590/2119 (75%), Gaps = 31/2119 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L S +LL DE I+ W NR LT+P P PV+IP FAE V R PDAVA+ Sbjct: 424 MTEDPD-RPLSSIELLTGDEPALIDRWSNRPALTEPAPAPVSIPQAFAEHVQRTPDAVAV 482 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G S TY +LDEASNRL H+LA+HG PG VA + PR +AI+S+L+VLKTGAAY+P Sbjct: 483 TFGATSLTYAQLDEASNRLGHLLADHGVGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVP 542 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAH +R+ F+++DA P A +TT+DLRSRLD +DL V+D+ DPA++ +P AL P P Sbjct: 543 IDPAHASSRMDFVLADAAPSAVITTSDLRSRLDDHDLLVVDVHDPAVEAQPGTALPWPAP 602 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +D AY+ YTSGTTG PK VA+ H NVT L+ +L A LP PG VW+Q HS FD SVWEI Sbjct: 603 EDTAYIIYTSGTTGTPKGVAIPHLNVTWLIESLDAGLP--PGNVWTQCHSSAFDFSVWEI 660 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALL G RL+VVPESV SSP+D H LL+ E+VSVL QTPSA MLSPEGLEST L+VAG Sbjct: 661 FGALLRGRRLLVVPESVASSPEDFHALLVAEQVSVLTQTPSAVAMLSPEGLESTALVVAG 720 Query: 301 EACPTELVDRWA-PGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 EACPT++VDRWA PGRVM++AYGPTE T+ A++S PL +FVLDK Sbjct: 721 EACPTDVVDRWAAPGRVMLDAYGPTETTVCASISTPLTAGDPVVPIGSPIAGAAMFVLDK 780 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WL+P P GVVGELY+AG GV GY+ RP LTASRFV PFG G RMYRTGDLV WG DG Sbjct: 781 WLQPVPAGVVGELYLAGRGVGHGYVRRPGLTASRFVPNPFGAPGSRMYRTGDLVCWGPDG 840 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVKIRG+RIELGE Q+ LA LDGV+QA V+AREDRPGDKRLVGYITGTAD Sbjct: 841 QLQYLGRADEQVKIRGFRIELGETQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGTAD 900 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA+LR LA+ LP YMVPTAV+VLD +PLT NGKLD+RALP+PEY AA +YRAP E Sbjct: 901 PAELRAQLADRLPPYMVPTAVMVLDALPLTGNGKLDKRALPSPEY--AAGEYRAPGDAIE 958 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 +ILAD+YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+FVEQT Sbjct: 959 EILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVICRPRDVFVEQTVARL 1018 Query: 600 XXXXXXXXESHV--VDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVV 657 + + DEG+GPV TPIMRWL+++DGP +FNQT++ APAGV DDV V Sbjct: 1019 ARVSQVAVDGELGAADEGIGPVQPTPIMRWLQDIDGPIDEFNQTMVLAAPAGVGVDDVAV 1078 Query: 658 ILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRL 717 +LQALLDRHA LRL ++D + W L VP G+V AR LRTVD L++ L AR+RL Sbjct: 1079 VLQALLDRHAMLRLCLDD--DGAGGWDLHVPPPGSVDARAILRTVDVLSEAALARARSRL 1136 Query: 718 DPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGT 777 +P AG M+SAVW T++L L++HHLAVDGVSWR L+ED+NIAWAQH +GQ I LP GT Sbjct: 1137 NPGAGLMLSAVWASATNELALVVHHLAVDGVSWRTLIEDINIAWAQHHSGQEIALPVPGT 1196 Query: 778 SFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETT 837 SFARWS++LAE+AK+ V A AW+ V + P LP V PD DTY + GQLSASLDV+TT Sbjct: 1197 SFARWSSILAEYAKSPAVVAAAAAWQQVVATPAVLPAVGPD-DTYASEGQLSASLDVQTT 1255 Query: 838 RQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRT 897 R LLGEVPAAF AGVQDILL+AFGLA TEF+ PIG+DVEGHGR++E+AS VDLSRT Sbjct: 1256 RLLLGEVPAAFHAGVQDILLIAFGLACTEFVG-GGAPIGIDVEGHGRHEEIASGVDLSRT 1314 Query: 898 VGWFTTKYPVALTV-ENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEV 956 VGWFTTKYPVALT+ + L W +VVAG+AALG ++K KEQLR+LP+GL+YGLLRYLNPE+ Sbjct: 1315 VGWFTTKYPVALTISQRLDWARVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEI 1374 Query: 957 DLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTI 1016 ++ G DP IGFNYLGRLG A +LS+E WR+ +P+PL HTVELNAGT+ Sbjct: 1375 EVQGPDPVIGFNYLGRLGGAAADLSDEHWRLSPDSPSVSAAAAAIPLPLGHTVELNAGTM 1434 Query: 1017 DTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLT 1076 DTD GP L A+WTWA S +EQ RLSRLWFEAL GICAHV+ GGGGLTPSD+AP L Sbjct: 1435 DTDAGPQLHANWTWARSVLTDEQLNRLSRLWFEALTGICAHVQAGGGGLTPSDIAPTLLD 1494 Query: 1077 QRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRD 1136 Q +I++L + YDV D+LPLTP+QQGLLFH+T + GD VYAVQL +T+ G LD HRL Sbjct: 1495 QGRIEQLERHYDVADILPLTPLQQGLLFHATGSHAEGD-VYAVQLSVTLRGALDPHRLHR 1553 Query: 1137 AVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERS 1196 A+HTVV RHPNLAARF + GEPVQ++ A+P +AWRYL+L G D+ D ++EQL A ER+ Sbjct: 1554 ALHTVVTRHPNLAARFCPELGEPVQIIPAEPEMAWRYLELDGGDI--DEQLEQLSADERA 1611 Query: 1197 AVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP 1256 AV +L +RP F AALIRT+ +HRFVLT HH+V+DGWSLP+LLQEIFA Y+G RLPA AP Sbjct: 1612 AVRELGDRPPFGAALIRTADTEHRFVLTVHHLVMDGWSLPVLLQEIFACYYGARLPAPAP 1671 Query: 1257 YRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGV--PGPRGIESYRVSAETTRALG 1314 YR FV WL WR VLDGF+TPTLVAP G PG RG+ S+RV+AETT A+ Sbjct: 1672 YRGFVTWLAARDVPAARAAWRAVLDGFDTPTLVAPRGADAPGRRGVASFRVAAETTSAVS 1731 Query: 1315 ELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPI 1374 ELAR + TT+NTVLQAAW QLLM +TGQ DVAFGTAVSGRPA+L GAESMVGLLINTVP+ Sbjct: 1732 ELARRRRTTVNTVLQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPV 1791 Query: 1375 RAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSA 1434 RA +A TT+ DL+ QLQ HN T+EH+HLALN+IH ++G +QLFDTL +YE+YPIDT+A Sbjct: 1792 RAHATAATTIADLVDQLQRAHNHTVEHQHLALNEIHRITGQDQLFDTLLVYENYPIDTAA 1851 Query: 1435 FMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLE 1494 +L TEF+ +YNHYPLS+ +PG ELGLR+E+DT VFD + I+TL DR ++LL Sbjct: 1852 LSAADDLTATEFSCHDYNHYPLSLQVVPGDELGLRLEFDTDVFDPAAIDTLADRLRKLLA 1911 Query: 1495 AMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAV 1554 AM DP R L S+D++D E T+L W NR L++P P S+PE+FA QV P A A+ Sbjct: 1912 AMPADPDRPLRSLDLLDATEHTRLQRWGNRPALSRPATGP-SLPELFAAQVANAPHAVAL 1970 Query: 1555 TFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLP 1614 + G S+ Y ELDEA+ +LA+LLA +GA PG VAL+ RSA+AIVA+LAVLKTGAAYLP Sbjct: 1971 RYAGRSMTYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYLP 2030 Query: 1615 IDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSP 1674 IDP++PA R+EFMLGDA PV AV+T DLR+R + F L VV+V A P L P+P Sbjct: 2031 IDPALPATRIEFMLGDAAPVVAVSTADLRARLEAFGLPVVDV--AATGAQPGGPLPAPAP 2088 Query: 1675 DDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEI 1734 D+IAY++YTSGTTGVPKGVA+TH NV Q+L++L A LP G G VWSQ HS FDVSV EI Sbjct: 2089 DNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLP-GTG-VWSQCHSYGFDVSVQEI 2146 Query: 1735 WGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAG 1794 WGAL GGRLV+VPES+ SPD+LHALL++E V VL QTPSA+ +SP L ALV+ G Sbjct: 2147 WGALAGGGRLVVVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLHA-ALVIGG 2205 Query: 1795 EACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEW 1854 E CP + DRWA RVMINAYGPTE+T+ A +S PL+ G+ P+GSPV FVLD W Sbjct: 2206 EPCPAALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDAW 2265 Query: 1855 LRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQ 1914 LR VP GV GELY+A LT RFVACPFG+ GARMYRTGDLVRW DG+ Sbjct: 2266 LRQVPAGVTGELYIAGAGVAAGYLGRPGLTAARFVACPFGDAGARMYRTGDLVRWDRDGR 2325 Query: 1915 LQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADP 1974 L Y+ RAD+QVKIRG+RIELGEI +AL+++DGV + VIAREDRPG+KR+VGY+TGTADP Sbjct: 2326 LHYVARADQQVKIRGHRIELGEIHSALAELDGVGEVAVIAREDRPGEKRIVGYLTGTADP 2385 Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKT 2034 AA R+ L RLPAYMVPAAV+ +E LPLT NGKLD RALPAPEY + YRAP T TE+ Sbjct: 2386 AAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEY-AGGAYRAPSTPTEEI 2444 Query: 2035 LAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +AGI+ VLG+ R AMRV AAVN LDA LSVR LFEAPT+A+L+ Sbjct: 2445 IAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQLA 2504 Query: 2095 LHVEHDAGERTDRVSFAAV 2113 + + G R FAAV Sbjct: 2505 ARL-GEGGHR-----FAAV 2517 Score = 1280 bits (3313), Expect = 0.0 Identities = 733/1494 (49%), Positives = 930/1494 (62%), Gaps = 63/1494 (4%) Query: 1116 VYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPM--IAWRY 1173 VY + + + G +D L A+H VV RH +L F G P QV+ I W+ Sbjct: 2547 VYNMVAALRLHGPVDIGALGAALHDVVTRHESLRTVFAATDGTPAQVVLPPDRADIGWQV 2606 Query: 1174 LDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGW 1233 +D G +P + + R DL RA L+R +H V HHI DGW Sbjct: 2607 IDASG--WSPARVDDAIRDTARHTF-DLAAEIPLRAVLLRCGAEEHLLVAVVHHIAADGW 2663 Query: 1234 SLPILLQEIFAGYFGHR-------LPAAAPYRNFVNWLXXXXXXXXXXX---------WR 1277 SL L++++ Y +P Y ++ W W Sbjct: 2664 SLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLRYWE 2723 Query: 1278 EVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHTTINTVLQAAW 1332 L G E PT P V RG + A+ + + LAR+ + T V+QAA Sbjct: 2724 HTLAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLARAHNATSFMVVQAAL 2783 Query: 1333 TQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQ 1390 LL +++ DVA G ++GR PA + +VG +NT+ +R VS D TVG+LL + Sbjct: 2784 AVLLAKVSASSDVAVGFPIAGRRDPA----LDDVVGFFVNTLVLRVDVSGDPTVGELLAR 2839 Query: 1391 LQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYPIDTS-AFMGVQELA 1442 ++ EH+ + LN ++ H + L P + S + V L Sbjct: 2840 VRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNIEPTELSLGQVRVTPLP 2899 Query: 1443 VTEFNNREYNHYPLSVMALPGHE---LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDD 1499 V R + L+ P +G VE+ T VFD + +E L R +R+L AM D Sbjct: 2900 VDTRTARMDLAWSLAERWAPDGSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLAAMTAD 2959 Query: 1500 PARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGE 1559 P RRLSS+D++D DE +LD NRA LT+P + P SIP +FA Q+ R P A A+T G Sbjct: 2960 PGRRLSSIDLLDPDEHARLDALGNRAALTRPQNPPTSIPAMFAAQMARTPHAVALTANGR 3019 Query: 1560 SLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSV 1619 S+ Y L+E ANQLA+ L YGA PG VAL++ RSA+A+ AIL VLK GAAYLPIDPS+ Sbjct: 3020 SVTYRRLEEHANQLAHQLIRYGAGPGDCVALLLERSAEAVAAILGVLKAGAAYLPIDPSL 3079 Query: 1620 PAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAY 1679 P+AR+EFML DA P A +T+ + R + V++VDDP++ P T P+PD+IAY Sbjct: 3080 PSARIEFMLTDAAPAAVLTSTEFHCRLQDYHQTVIDVDDPSIREQPVTAPPAPAPDNIAY 3139 Query: 1680 MIYTSGTTGVPKGVAITHGNVTQVLDTLPAE-LPAGPGAVWSQWHSLVFDVSVWEIWGAL 1738 +IYTSGTTGVPKGVA+TH N TQ+ +L A LPA PG VW Q HSL FD SVWEI+GAL Sbjct: 3140 LIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWEIFGAL 3199 Query: 1739 LHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAV----RMMSPEGLEGTALVVAG 1794 L+GGR+++VP+ + SP+DL ALL+ E V+VL QTPSA R S L ++ G Sbjct: 3200 LNGGRVLVVPDDVVRSPEDLCALLIEERVDVLSQTPSAFDALQRADSARRLNPQTVIFGG 3259 Query: 1795 EACPTEVVDRWAVDRV----MINAYGPTESTIYAAISAPLSPGSD--VVPIGSPVPKGAT 1848 EA + W +IN YG TE+T++A+ + D V PIG P+ Sbjct: 3260 EALIPHRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDIDGNVSPIGMPLAHLGF 3319 Query: 1849 FVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVR 1908 FVLD WLRPVP GV GELY+A LT +RFVACPFG G RMYRTGDL R Sbjct: 3320 FVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACPFGGAGERMYRTGDLAR 3379 Query: 1909 WGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYI 1968 WG DGQLQYLGRADEQVKIRGYRIELGEIQ+AL+++D V+QA VIAREDRPGD+RLV Y+ Sbjct: 3380 WGADGQLQYLGRADEQVKIRGYRIELGEIQSALAELDSVEQAAVIAREDRPGDERLVAYV 3439 Query: 1969 TGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPE 2028 TGTADPA R+ LT RLPAY+VPAAV+ L+ LPLT +GKLD ALPAP+YQ + Y AP Sbjct: 3440 TGTADPAQLRTALTERLPAYLVPAAVLVLDALPLTPSGKLDTGALPAPDYQGPEDYLAPA 3499 Query: 2029 TETEKTLAGIFAHVLGV-ERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEA 2087 E+ LA ++A VLG+ R AMR+ AA+ ALD L VR +FEA Sbjct: 3500 GAVEEILAWLYAQVLGLPRRVGVQESFFDLGGDSLSAMRLVAAIYNALDIHLPVRAVFEA 3559 Query: 2088 PTVAKLSLHVEHD-AGERTDRVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXXXXXXX 2146 P+V LS + D A + R FA+VHG D TEV+A DLTLDKFI Sbjct: 3560 PSVRSLSQRLNADPAVAQGLRADFASVHGRDATEVYASDLTLDKFIDAATLSAAPALPGP 3619 Query: 2147 XGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDT-DP 2205 V+TVLLTGATGFLGRYL+L+WL +L D K+ICLVR SD+DARRRLE TFD+ DP Sbjct: 3620 GAEVRTVLLTGATGFLGRYLVLQWLERLELADGKLICLVRAASDDDARRRLERTFDSGDP 3679 Query: 2206 LLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELF 2265 L ++F+ELA + L+V+AGDKG+ NLGLD++TWQRLA++VDLIVD+AA VN VLPY ELF Sbjct: 3680 ALLRYFHELAADHLEVIAGDKGRANLGLDDRTWQRLADTVDLIVDAAAVVNGVLPYQELF 3739 Query: 2266 GPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYAN 2325 GPNV GTAELIR AL+++LKP+++VST++VG QIEPS FTE ADIR+ R I+ GY N Sbjct: 3740 GPNVAGTAELIRLALSTRLKPYSYVSTANVGDQIEPSAFTEDADIRVAGPIRTIDGGYGN 3799 Query: 2326 GYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGV 2385 GYGNSKWAGEVLLREAHD CGLPV+VFR MI+ D +YAGQLN++D +R++ S+VA+GV Sbjct: 3800 GYGNSKWAGEVLLREAHDLCGLPVSVFRCDMILADTSYAGQLNLSDMFTRLLFSVVASGV 3859 Query: 2386 APGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHD 2445 AP SFY+ +G RQRAHFD LPV+FVA+AI LG QV R GF TYHVMNPHD Sbjct: 3860 APRSFYRLDAHGNRQRAHFDALPVEFVAEAIATLGAQVGR----DAGIGFATYHVMNPHD 3915 Query: 2446 DGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAG 2505 DGIG+D Y+DWLIEAGY IER++DF +WL R E AL L ++QR SVLQ+L L K A Sbjct: 3916 DGIGLDEYVDWLIEAGYLIERVDDFDQWLHRMETALHALPERQRHQSVLQLLALRK--AR 3973 Query: 2506 ELQPPVPTRGSFAPADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 + P P RG P +RF+AAV++A IG + +IPH+T VIVKYVTDLQLLGLL Sbjct: 3974 HVPPADPARGCLGPTERFRAAVQEAKIGADNDIPHITAPVIVKYVTDLQLLGLL 4027 Score = 739 bits (1908), Expect = 0.0 Identities = 454/961 (47%), Positives = 570/961 (59%), Gaps = 55/961 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P R L S DLLD EH +++ WGNR L+ P P ++P LFA QV AP AVAL Sbjct: 1913 MPADPD-RPLRSLDLLDATEHTRLQRWGNRPALSRPATGP-SLPELFAAQVANAPHAVAL 1970 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS TYRELDEAS RLAH+LA HGA PG VA L RS EAI+++L+VLKTGAAYLP Sbjct: 1971 RYAGRSMTYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYLP 2030 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P RI FM+ DA PV A++TADLR+RL+ + L V+D+A A +P L P P Sbjct: 2031 IDPALPATRIEFMLGDAAPVVAVSTADLRARLEAFGLPVVDVA--ATGAQPGGPLPAPAP 2088 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D++AY+ YTSGTTGVPK VAVTH NV QL+ +LHA LP G G VWSQ HS FDVSV EI Sbjct: 2089 DNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLP-GTG-VWSQCHSYGFDVSVQEI 2146 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGAL GGRLVVVPESV SSPD+LH LLI E V+VL QTPSA LSP L + L++ G Sbjct: 2147 WGALAGGGRLVVVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLHAA-LVIGG 2205 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 E CP L DRWAPGRVMINAYGPTE T+ A +S PL LFVLD W Sbjct: 2206 EPCPAALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDAW 2265 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LR P GV GELY+AG GVA GY+GRP LTA+RFVACPFG+ G RMYRTGDLVRW DG+ Sbjct: 2266 LRQVPAGVTGELYIAGAGVAAGYLGRPGLTAARFVACPFGDAGARMYRTGDLVRWDRDGR 2325 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L Y+ RAD+QVKIRG+RIELGEI +ALA+LDGV + VIAREDRPG+KR+VGY+TGTADP Sbjct: 2326 LHYVARADQQVKIRGHRIELGEIHSALAELDGVGEVAVIAREDRPGEKRIVGYLTGTADP 2385 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A +R LAE LPAYMVP AV+ ++ +PLT NGKLD RALPAPEY A YRAPSTP E+ Sbjct: 2386 AAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEYAGGA--YRAPSTPTEE 2443 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCR--PRDIFVEQTXXX 598 I+A +Y QVLG+ RVGVDDSFFDLGGDS+ +M+V+A A G+ R R +F T Sbjct: 2444 IIAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNA-GLDARLSVRVLFEAPTIAQ 2502 Query: 599 XXXXXXXXXESHVVDEGVGPVVATPI------MRWLREVDGPTGQFNQTVITQAPAGVTE 652 P+ + ++ ++ GP+ +N + V Sbjct: 2503 LAARLGEGGHRFAAVVAAERPAVVPLSFAQSRLWFIGQLHGPSPVYNMVAALRLHGPVDI 2562 Query: 653 DDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGAR--ECLRTVDALTDDVL 710 + L ++ RH +LR T + T +L P+ +G + + A DD + Sbjct: 2563 GALGAALHDVVTRHESLRTVFAAT-DGTPAQVVLPPDRADIGWQVIDASGWSPARVDDAI 2621 Query: 711 VE-ARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCT 766 + AR+ D AA + AV +R E LV ++HH+A DG S L+ DL A+A Sbjct: 2622 RDTARHTFDLAAEIPLRAVLLRCGAEEHLLVAVVHHIAADGWSLTPLVRDLARAYASRSA 2681 Query: 767 GQS---IELPAGGTSFARWSALLAEHAKTDTVRDLADA----W-RAVTSVPQALPPVQPD 818 G+ + LP + W A+ D L W + +P+ L + D Sbjct: 2682 GRVPDWVPLPVQYVDYTLWQR--AQFGDLDDPHSLIAGQLRYWEHTLAGMPERL-ELPTD 2738 Query: 819 TDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLV---AFGLAWTEFLNRSDTPI 875 V A AS+ VE QL ++ RA +V A + + SD + Sbjct: 2739 RPYPVVADFRGASVAVEWPAQLQQQISRLARAHNATSFMVVQAALAVLLAKVSASSDVAV 2798 Query: 876 GVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKE 935 G + GR D DV VG+F V L V+GD +G ++ V++ Sbjct: 2799 GFPIA--GRRDPALDDV-----VGFF---------VNTLVLRVDVSGDPTVGELLARVRQ 2842 Query: 936 Q 936 + Sbjct: 2843 R 2843 Score = 724 bits (1870), Expect = 0.0 Identities = 445/1004 (44%), Positives = 589/1004 (58%), Gaps = 36/1004 (3%) Query: 1111 GIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIA 1170 G + + L + I G + + L A+ VA F E G+ VQ I Sbjct: 32 GFAGTQWQLGLLVKIDGKVHRDALEQAITQAVAEAEPGRVSFFELDGQVVQ-----KPID 86 Query: 1171 WRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPT----FRAALIRTSGNQHRFVLTFH 1226 + +++L DLT DH A E S+ P F+ L +T ++ H Sbjct: 87 YPHVELAFHDLT-DHADPVAEAREMSSAIQRTPMPLNGQMFKFVLFQTGHDEFYLFGCCH 145 Query: 1227 HIVIDGWSLPILLQEIFAGYF----GHRLPAA--APYRNFVN----WLXXXXXXXXXXXW 1276 HI IDG + ++ + + Y G +P A ++ ++ + W Sbjct: 146 HIAIDGLGMALVCRRVATIYSAMVAGKPIPDAYFGTVQDLIDLESGYEASPDYAEDKAYW 205 Query: 1277 REVLDGFETPTLVAPPGVPGPRGIESYRVSAE----TTRALGELARSQHTTINTVLQAAW 1332 E L E+ + P G R S S + + EL++ +V AA Sbjct: 206 SEHLPP-ESGPVDRLPDAEGERDHYSPSASVQLDPSVANRIKELSKKLAIRRFSVTTAAC 264 Query: 1333 TQLLMRMTGQ-RDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQL 1391 L+ +G +VA VS R ++++ +L VP+ + ++TV D + + Sbjct: 265 ALLVRGWSGSGSEVALDFPVSRRVRP--ESKTLPAMLAGVVPLVLSTAPESTVADFCKHV 322 Query: 1392 QSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREY 1451 + L H+ ++ + G Q + + + P + + + N+ Sbjct: 323 DKRIRELLAHQRFPVHTLEG-DGLRQAPNRVGI-NFIPSRLTLDLAGSPATASYTNHGPV 380 Query: 1452 NHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVD 1511 H+ L + G +L L F + L R Q++L AM +DP R LSS++++ Sbjct: 381 GHFGLFFLGA-GDQLFLSTAGPGQPFASFGVADLAGRLQQILAAMTEDPDRPLSSIELLT 439 Query: 1512 DDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAAN 1571 DE +D W+NR LT+P +P SIP+ FA V+R P+A AVTF SL Y +LDEA+N Sbjct: 440 GDEPALIDRWSNRPALTEPAPAPVSIPQAFAEHVQRTPDAVAVTFGATSLTYAQLDEASN 499 Query: 1572 QLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDA 1631 +L +LLA +G PG VA+M PR ADAIV++LAVLKTGAAY+PIDP+ ++R++F+L DA Sbjct: 500 RLGHLLADHGVGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVPIDPAHASSRMDFVLADA 559 Query: 1632 KPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPK 1691 P A +TT DLRSR D DL VV+V DPAVE P T L P+P+D AY+IYTSGTTG PK Sbjct: 560 APSAVITTSDLRSRLDDHDLLVVDVHDPAVEAQPGTALPWPAPEDTAYIIYTSGTTGTPK 619 Query: 1692 GVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESI 1751 GVAI H NVT ++++L A LP PG VW+Q HS FD SVWEI+GALL G RL++VPES+ Sbjct: 620 GVAIPHLNVTWLIESLDAGLP--PGNVWTQCHSSAFDFSVWEIFGALLRGRRLLVVPESV 677 Query: 1752 AGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAV-DRV 1810 A SP+D HALLV+E V+VL QTPSAV M+SPEGLE TALVVAGEACPT+VVDRWA RV Sbjct: 678 ASSPEDFHALLVAEQVSVLTQTPSAVAMLSPEGLESTALVVAGEACPTDVVDRWAAPGRV 737 Query: 1811 MINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAX 1870 M++AYGPTE+T+ A+IS PL+ G VVPIGSP+ A FVLD+WL+PVP GVVGELYLA Sbjct: 738 MLDAYGPTETTVCASISTPLTAGDPVVPIGSPIAGAAMFVLDKWLQPVPAGVVGELYLAG 797 Query: 1871 XXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGY 1930 LT +RFV PFG PG+RMYRTGDLV WG DGQLQYLGRADEQVKIRG+ Sbjct: 798 RGVGHGYVRRPGLTASRFVPNPFGAPGSRMYRTGDLVCWGPDGQLQYLGRADEQVKIRGF 857 Query: 1931 RIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMV 1990 RIELGE Q+ L+ +DGV+QA V+AREDRPGDKRLVGYITGTADPA R++L +RLP YMV Sbjct: 858 RIELGETQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGTADPAELRAQLADRLPPYMV 917 Query: 1991 PAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXX 2050 P AV+ L+ LPLT NGKLD+RALP+PEY +A YRAP E+ LA I+A VLGVER Sbjct: 918 PTAVMVLDALPLTGNGKLDKRALPSPEY-AAGEYRAPGDAIEEILADIYAQVLGVERVGV 976 Query: 2051 XXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +M+V A A R +F TVA+L+ Sbjct: 977 DDSFFDLGGDSILSMQVVARARAA-GVICRPRDVFVEQTVARLA 1019 Score = 649 bits (1674), Expect = 0.0 Identities = 349/588 (59%), Positives = 418/588 (71%), Gaps = 14/588 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P R L S DLLD DEH +++ GNRA LT P P +IPA+FA Q+ R P AVAL Sbjct: 2956 MTADPGRR-LSSIDLLDPDEHARLDALGNRAALTRPQNPPTSIPAMFAAQMARTPHAVAL 3014 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 + RS TYR L+E +N+LAH L +GA PG VA L+ RS EA+ +IL VLK GAAYLP Sbjct: 3015 TANGRSVTYRRLEEHANQLAHQLIRYGAGPGDCVALLLERSAEAVAAILGVLKAGAAYLP 3074 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP+ P ARI FM++DA P A LT+ + RL Y VID+ DP+I +P A P P Sbjct: 3075 IDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQDYHQTVIDVDDPSIREQPVTAPPAPAP 3134 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHA-DLPSGPGQVWSQWHSLVFDVSVWE 239 D++AY+ YTSGTTGVPK VAVTH N TQL ++L A LP+ PG+VW Q HSL FD SVWE Sbjct: 3135 DNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWE 3194 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGML----SPEGLESTT 295 I+GALL+GGR++VVP+ V SP+DL LLI E+V VL QTPSA L S L T Sbjct: 3195 IFGALLNGGRVLVVPDDVVRSPEDLCALLIEERVDVLSQTPSAFDALQRADSARRLNPQT 3254 Query: 296 LIVAGEACPTELVDRWAPGRV----MINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXX 351 +I GEA + W G +IN YG TE T++A+ E + Sbjct: 3255 VIFGGEALIPHRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDIDGNVSPIGMPL 3314 Query: 352 XXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRT 409 L FVLD WLRP P GV GELY+AG GVA GY+GRP LTASRFVACPFG GERMYRT Sbjct: 3315 AHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACPFGGAGERMYRT 3374 Query: 410 GDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKR 469 GDL RWG+DGQL+YLGRADEQVKIRGYRIELGEIQ+ALA+LD V+QA VIAREDRPGD+R Sbjct: 3375 GDLARWGADGQLQYLGRADEQVKIRGYRIELGEIQSALAELDSVEQAAVIAREDRPGDER 3434 Query: 470 LVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAAN 529 LV Y+TGTADPAQLRTAL E LPAY+VP AV+VLD +PLT +GKLD ALPAP+Y+ Sbjct: 3435 LVAYVTGTADPAQLRTALTERLPAYLVPAAVLVLDALPLTPSGKLDTGALPAPDYQ-GPE 3493 Query: 530 DYRAPSTPAEQILADVYAQVLGV-ERVGVDDSFFDLGGDSILSMQVVA 576 DY AP+ E+ILA +YAQVLG+ RVGV +SFFDLGGDS+ +M++VA Sbjct: 3494 DYLAPAGAVEEILAWLYAQVLGLPRRVGVQESFFDLGGDSLSAMRLVA 3541 >tr|A0QHN8|A0QHN8_MYCA1 Tax_Id=243243 SubName: Full=Linear gramicidin synthetase subunit D; EC=1.-.-.-; EC=5.1.1.-;[Mycobacterium avium] Length = 3415 Score = 2572 bits (6667), Expect = 0.0 Identities = 1333/2114 (63%), Positives = 1592/2114 (75%), Gaps = 37/2114 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L S +LL DE I+ W NR LT+P P PV+IP FAE V R PDAVA+ Sbjct: 416 MTEDPD-RPLSSIELLTGDEPALIDRWSNRPALTEPAPAPVSIPQAFAEHVQRTPDAVAV 474 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G S TY +LDEASNRL H+LA+HG PG VA + PR +AI+S+L+VLKTGAAY+P Sbjct: 475 TFGATSLTYAQLDEASNRLGHLLADHGVGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVP 534 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAH +R+ F+++DA P A +TT+DLRSRLD +DL VID+ DPA++ +P AL P P Sbjct: 535 IDPAHASSRMDFVLADAAPSAVITTSDLRSRLDDHDLLVIDVHDPAVEAQPGTALPWPAP 594 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 ++ AY+ YTSGTTG PK VA+ H NVT L+ +L A LP PG VW+Q HS FD SVWEI Sbjct: 595 ENTAYIIYTSGTTGTPKGVAIPHLNVTWLIESLDAGLP--PGNVWTQCHSSAFDFSVWEI 652 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALL G RL+VVPESV SSP+D H LL+ E+VSVL QTPSA MLSPEGLEST L+VAG Sbjct: 653 FGALLRGRRLLVVPESVASSPEDFHALLVAEQVSVLTQTPSAVAMLSPEGLESTALVVAG 712 Query: 301 EACPTELVDRWA-PGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 EACPT++VDRWA PGRVM++AYGPTE T+ A++S PL +FVLDK Sbjct: 713 EACPTDVVDRWAAPGRVMLDAYGPTETTVCASISTPLTAGDPVVPIGSPIAGAAMFVLDK 772 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WL+P P GVVGELY+AG GV GY+ RP LTASRFV PFG G RMYRTGDLV WG DG Sbjct: 773 WLQPVPAGVVGELYLAGRGVGHGYVRRPGLTASRFVPNPFGAPGSRMYRTGDLVCWGPDG 832 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVKIRG+RIELGEIQ+ LA LDGV+QA V+AREDRPGDKRLVGYITGTAD Sbjct: 833 QLQYLGRADEQVKIRGFRIELGEIQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGTAD 892 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA+LR LA+ LP YMVPTAV+VLD +PLT NGKLD+RALP+PEY AA +YRAP E Sbjct: 893 PAELRAQLADRLPPYMVPTAVMVLDALPLTGNGKLDKRALPSPEY--AAGEYRAPGDAIE 950 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 +ILAD+YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+FVEQT Sbjct: 951 EILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVICRPRDVFVEQTVARL 1010 Query: 600 XXXXXXXXESHV--VDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVV 657 + + DEG+GPV TPIMRWL+++DGP +FNQT++ APAGV DDV V Sbjct: 1011 ARVSQVAVDGELGAADEGIGPVRPTPIMRWLQDIDGPIDEFNQTMVLAAPAGVGVDDVAV 1070 Query: 658 ILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRL 717 +LQALLDRH LRLRV+D + WSL PE G+V A +CLR VD+L+D LVEAR+RL Sbjct: 1071 VLQALLDRHPMLRLRVQD--DGAGGWSLEAPEVGSVRAADCLRAVDSLSDAALVEARSRL 1128 Query: 718 DPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGT 777 + + G ++SAVW ETSQL L++HHLAVDGVSWR L+ED+NIAWAQH GQ I LP GT Sbjct: 1129 NVSDGVLLSAVWASETSQLALVVHHLAVDGVSWRTLIEDINIAWAQHQGGQEIALPVPGT 1188 Query: 778 SFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETT 837 SFARWS++LAE+AK+ V A AW+ V + P LP V PD DTY +AGQLSASLDVETT Sbjct: 1189 SFARWSSILAEYAKSPAVVAAAAAWQQVVATPAVLPAVGPD-DTYASAGQLSASLDVETT 1247 Query: 838 RQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRT 897 R LLGEVPAAF AGVQDILL+AFGLA TEF+ PIG+DVEGHGR++E+AS VDLSRT Sbjct: 1248 RLLLGEVPAAFHAGVQDILLIAFGLACTEFVG-GGAPIGIDVEGHGRHEEIASGVDLSRT 1306 Query: 898 VGWFTTKYPVALTV-ENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEV 956 VGWFTTKYPVAL + L W +VVAG+AALG ++K KEQLR+LP+GL+YGLLRYLNPE+ Sbjct: 1307 VGWFTTKYPVALRMGRRLDWARVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEI 1366 Query: 957 DLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTI 1016 ++ G DP IGFNYLGRLGAGA +LSEE+WR+ VPMPL HTVELNAGT+ Sbjct: 1367 EVQGPDPVIGFNYLGRLGAGA-DLSEEMWRVSADSLSSAAVATAVPMPLAHTVELNAGTM 1425 Query: 1017 DTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLT 1076 DTD GP L A+W WA S +EQ RLSRLWFEAL GICAHV+ GGGGLTPSD+APARL Sbjct: 1426 DTDAGPQLHANWRWARSVLTDEQLNRLSRLWFEALTGICAHVQAGGGGLTPSDIAPARLD 1485 Query: 1077 QRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRD 1136 Q+QIDEL Q++ + DVLPL+PVQQGLLFH+ FA+ + +D+YAVQL IT++G LD HRLRD Sbjct: 1486 QQQIDELCQQHQIADVLPLSPVQQGLLFHTGFAQEL-EDLYAVQLGITVSGTLDPHRLRD 1544 Query: 1137 AVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERS 1196 AV V RHPNL ARF ++FGEPVQ++ A+P +AWRYL+L G D+ D ++EQL A ER+ Sbjct: 1545 AVQNAVNRHPNLVARFFDEFGEPVQIIPAEPEMAWRYLELDGGDI--DGQLEQLSADERA 1602 Query: 1197 AVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP 1256 AVCDL +P FRAALIR + ++HR +LT HHIVIDGWSLP+LLQE+FAGY+G RLPA Sbjct: 1603 AVCDLAGQPAFRAALIRIADDRHRLLLTIHHIVIDGWSLPVLLQEVFAGYYGQRLPAPPS 1662 Query: 1257 YRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGEL 1316 YR+++ WL WRE L GFETPTLVAPPG G R + +Y VSA+TT+ALGEL Sbjct: 1663 YRSYLMWLSAQDRAAAQDAWREALAGFETPTLVAPPGKIGRRAVATYTVSADTTKALGEL 1722 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA 1376 ARS TT++TVLQ AW QLL +TGQ DVAFGTAVSGRP +L GA++MVGLLINTVP+RA Sbjct: 1723 ARSSRTTVSTVLQGAWAQLLTWLTGQHDVAFGTAVSGRPTELPGADAMVGLLINTVPVRA 1782 Query: 1377 KVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFM 1436 ++A TTV DLL QLQ H DTLEHEHLALN+IH V+GH+QLFDTLFLYE+YPID SA + Sbjct: 1783 DIAAATTVVDLLEQLQRAHADTLEHEHLALNEIHRVTGHDQLFDTLFLYENYPIDASALL 1842 Query: 1437 GVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAM 1496 V ELAVTEF++RE+NHYPLSV+A PGHEL LRVEYDT VFD + IETLI+R +++L AM Sbjct: 1843 DVHELAVTEFSSREFNHYPLSVVATPGHELSLRVEYDTEVFDEAGIETLIERLRQVLAAM 1902 Query: 1497 IDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTF 1556 DP +RLS++D++D E +LD W NRAVLT+ + SIP +FA QV R +A A+T Sbjct: 1903 TTDPGQRLSAIDLLDAAEHERLDAWGNRAVLTRRPAAQASIPALFAAQVARAADAVAITC 1962 Query: 1557 EGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPID 1616 S Y E++E+AN+LA+LL+ GA PG+ VA+++PRSA+A+VAI AVLKTGAAY+PID Sbjct: 1963 GERSFTYREVEESANRLAHLLSGQGAGPGQRVAVVIPRSAEAVVAIFAVLKTGAAYVPID 2022 Query: 1617 PSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDD 1676 P VPAARL+F+L D+ PVAAVTT ++R R DGF Q+++ DDPAV P+T L P+ D+ Sbjct: 2023 PGVPAARLQFVLADSAPVAAVTTAEVRDRLDGFTGQIIDFDDPAVAEQPATGLPVPAADN 2082 Query: 1677 IAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWG 1736 IAY+IYTSGTTG+PKGVAI H NVT +L+TL A+L G G VW+Q HSL FD SVWEI+G Sbjct: 2083 IAYIIYTSGTTGIPKGVAIPHRNVTLLLETLDAQL--GLGQVWTQCHSLAFDFSVWEIFG 2140 Query: 1737 ALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA------VRMMSPE---GLEG 1787 ALLHGGRLVIVP+ I SP+DLHALLV E V+VL QTPSA ++PE L+ Sbjct: 2141 ALLHGGRLVIVPDDIVRSPEDLHALLVREQVSVLSQTPSAFYALQSADALAPELGQQLKL 2200 Query: 1788 TALVVAGEACPTEVVDRW-----AVDRVMINAYGPTESTIYAAIS--APLSPGSDVVPIG 1840 +V GEA + W + R MIN YG TE+T++A+ S V PIG Sbjct: 2201 QTVVFGGEALEPHRLATWLHRHPGLPR-MINMYGITETTVHASFREIVDADVDSSVSPIG 2259 Query: 1841 SPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARM 1900 P+ A FVLD WLRPVP GVVGELY+A L+ TRFVACPFG PGARM Sbjct: 2260 VPLANLAFFVLDGWLRPVPVGVVGELYVAGGGLATGYVGRPGLSATRFVACPFGGPGARM 2319 Query: 1901 YRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPG 1960 YRTGDLVRWG DGQLQY+GRAD QVKIRGYRIELGEIQAAL+ +DGV+ A VIAREDRPG Sbjct: 2320 YRTGDLVRWGADGQLQYMGRADAQVKIRGYRIELGEIQAALAGLDGVEHAAVIAREDRPG 2379 Query: 1961 DKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS 2020 DKRLVGYITGTADPA R++L RLP YMVP+AVV L+ LPLTVNGKLD RALPAPEY Sbjct: 2380 DKRLVGYITGTADPAEVRAQLGERLPGYMVPSAVVVLDALPLTVNGKLDTRALPAPEYSD 2439 Query: 2021 AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLS 2080 RYRAP T E+ LA I+A VLGVER +M+V A A Sbjct: 2440 VDRYRAPVTAIEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GVICR 2498 Query: 2081 VRTLFEAPTVAKLS 2094 R +F TVA+L+ Sbjct: 2499 PRDVFTEQTVARLA 2512 Score = 1868 bits (4839), Expect = 0.0 Identities = 968/1520 (63%), Positives = 1150/1520 (75%), Gaps = 32/1520 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L + DLLD EH++++ WGNRAVLT +IPALFA QV RA DAVA+ Sbjct: 1902 MTTDPGQR-LSAIDLLDAAEHERLDAWGNRAVLTRRPAAQASIPALFAAQVARAADAVAI 1960 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G+RS+TYRE++E++NRLAH+L+ GA PG VA +IPRS EA+++I +VLKTGAAY+P Sbjct: 1961 TCGERSFTYREVEESANRLAHLLSGQGAGPGQRVAVVIPRSAEAVVAIFAVLKTGAAYVP 2020 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP P AR+ F+++D+ PVAA+TTA++R RLD + +ID DPA+ +P+ L P Sbjct: 2021 IDPGVPAARLQFVLADSAPVAAVTTAEVRDRLDGFTGQIIDFDDPAVAEQPATGLPVPAA 2080 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D++AY+ YTSGTTG+PK VA+ H NVT L+ L A L G GQVW+Q HSL FD SVWEI Sbjct: 2081 DNIAYIIYTSGTTGIPKGVAIPHRNVTLLLETLDAQL--GLGQVWTQCHSLAFDFSVWEI 2138 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPE---GL 291 +GALLHGGRLV+VP+ + SP+DLH LL+ E+VSVL QTPSA A L+PE L Sbjct: 2139 FGALLHGGRLVIVPDDIVRSPEDLHALLVREQVSVLSQTPSAFYALQSADALAPELGQQL 2198 Query: 292 ESTTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSEPLXXXXXXXXXXX 347 + T++ GEA + W PG MIN YG TE T++A+ E + Sbjct: 2199 KLQTVVFGGEALEPHRLATWLHRHPGLPRMINMYGITETTVHASFREIVDADVDSSVSPI 2258 Query: 348 XXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 L FVLD WLRP P GVVGELYVAG G+ATGY+GRP L+A+RFVACPFG G R Sbjct: 2259 GVPLANLAFFVLDGWLRPVPVGVVGELYVAGGGLATGYVGRPGLSATRFVACPFGGPGAR 2318 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLVRWG+DGQL+Y+GRAD QVKIRGYRIELGEIQAALA LDGV+ A VIAREDRP Sbjct: 2319 MYRTGDLVRWGADGQLQYMGRADAQVKIRGYRIELGEIQAALAGLDGVEHAAVIAREDRP 2378 Query: 466 GDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 GDKRLVGYITGTADPA++R L E LP YMVP+AVVVLD +PLTVNGKLD RALPAPEY Sbjct: 2379 GDKRLVGYITGTADPAEVRAQLGERLPGYMVPSAVVVLDALPLTVNGKLDTRALPAPEY- 2437 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQC 585 S + YRAP T E+ILAD+YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ C Sbjct: 2438 SDVDRYRAPVTAIEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVIC 2497 Query: 586 RPRDIFVEQTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVIT 644 RPRD+F EQT + VVDEG G VVATPIMRWL+ +DGP QFNQT++ Sbjct: 2498 RPRDVFTEQTVARLARVATVATGDDDVVDEGTGRVVATPIMRWLQNMDGPVEQFNQTMVL 2557 Query: 645 QAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA 704 APAGVT DDV +LQALLDRHA LRLRVED + WSL VPEAG+V A +CL TVDA Sbjct: 2558 AAPAGVTPDDVAAVLQALLDRHAMLRLRVED--DGAGGWSLEVPEAGSVQAADCLETVDA 2615 Query: 705 LTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 L+ LV+AR+RL+ A G +V AVW ETSQL L+IHHLAVDGVSWR L+EDLNIAWAQH Sbjct: 2616 LSPAALVDARSRLNLADGILVRAVWASETSQLALIIHHLAVDGVSWRTLIEDLNIAWAQH 2675 Query: 765 CTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVT 824 +GQ + LP GG SFARWSALL +HA+ V + A+ WR V +VP LP QP DTY T Sbjct: 2676 HSGQPVALPTGGMSFARWSALLEDHARRPEVVERAEDWRQVAAVPAVLPGAQPG-DTYAT 2734 Query: 825 AGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGR 884 AGQLSASLDVETTR LLGEVPAAF AGVQDILL+AFGLAWT+F+ + PIG+DVEGHGR Sbjct: 2735 AGQLSASLDVETTRLLLGEVPAAFHAGVQDILLIAFGLAWTQFIG-TGAPIGIDVEGHGR 2793 Query: 885 YDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGL 944 +EL VDLSRTVGWFT KYPVAL + L W QVV GD ALG +VK KEQLR+LP+GL Sbjct: 2794 SEELGPQVDLSRTVGWFTAKYPVALRLGGLSWGQVVGGDEALGAVVKEAKEQLRALPDGL 2853 Query: 945 TYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMP 1004 TYGLLRYLNP+ L SDP I FNYLGRLG GA ELS ELWR+ V +P Sbjct: 2854 TYGLLRYLNPQAGLDVSDPAIAFNYLGRLGGGAAELSPELWRLSPDSFALAGAAGAVELP 2913 Query: 1005 LMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGG 1064 L HTVELNAGT+DT++GP L+A+WTWA SA D++Q RLS LWF+ALAGIC HVR GGGG Sbjct: 2914 LPHTVELNAGTMDTEDGPHLQANWTWARSALDDKQIGRLSELWFDALAGICTHVRAGGGG 2973 Query: 1065 LTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGI--GDDVYAVQLD 1122 LTPSDVA ARLTQR +DEL+QRY V DVLPLTP+QQGLLFH+ A+G +D+YAVQLD Sbjct: 2974 LTPSDVAAARLTQRDLDELAQRYRVADVLPLTPLQQGLLFHAGTAQGSQEPEDLYAVQLD 3033 Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDL-RGDDL 1181 I++TG +D RLR+AV TV+ RHPN+ A F E FGEPVQ+L+A+P +AW+Y++L G DL Sbjct: 3034 ISVTGAVDPDRLREAVRTVITRHPNVVAHFSEDFGEPVQILSAEPELAWQYVELDAGADL 3093 Query: 1182 TPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQE 1241 D ++E+L +AER AV DL + P FR ALIRT+ + +RFVLT HHIV+DGWS P+LLQE Sbjct: 3094 --DEQVERLSSAERVAVGDLAQ-PPFRGALIRTAEDAYRFVLTNHHIVLDGWSKPLLLQE 3150 Query: 1242 IFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG--VPGPRG 1299 IFA YFG RLPA PYRNF+ WL WREVL GF+TPTLV P G GPRG Sbjct: 3151 IFAAYFGVRLPAPVPYRNFITWLSAQDRAAAQAAWREVLAGFDTPTLVGPSGRMALGPRG 3210 Query: 1300 IESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLA 1359 + + V A+T+R LGELARS TT++TVLQAAW QLLM +TGQ DV FGTAVSGRP +LA Sbjct: 3211 VAEFHVPADTSRLLGELARSCRTTVSTVLQAAWAQLLMWLTGQHDVVFGTAVSGRPTELA 3270 Query: 1360 GAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLF 1419 G+ESMVGLLINTVP+RA + A+TT+ DLL QLQ + TLEH+HLALNDIH V+GH+Q+F Sbjct: 3271 GSESMVGLLINTVPVRATIGAETTIADLLDQLQRAYTHTLEHQHLALNDIHRVTGHDQIF 3330 Query: 1420 DTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDV 1479 DT+F+YE+YPIDT+A V EL +T F NREYNHYPLSV A+PGHE+GLRVE+DT VF Sbjct: 3331 DTMFVYENYPIDTAALSAVDELTITGFTNREYNHYPLSVQAVPGHEIGLRVEFDTDVFGE 3390 Query: 1480 SEIETLIDRFQRLLEAMIDD 1499 + IE LI+RF+R+LEAM D Sbjct: 3391 ARIEKLIERFRRVLEAMTVD 3410 Score = 724 bits (1869), Expect = 0.0 Identities = 444/1004 (44%), Positives = 590/1004 (58%), Gaps = 36/1004 (3%) Query: 1111 GIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIA 1170 G + + L + I G + + L A+ VA F E G+ VQ I Sbjct: 24 GFAGTQWQLGLLVKIDGKVHRDALEQAITQAVAEAEPGRVSFFEVDGQVVQ-----KPID 78 Query: 1171 WRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPT----FRAALIRTSGNQHRFVLTFH 1226 + +++L DLT DH A E S+ P F+ L +T ++ H Sbjct: 79 YPHVELAFHDLT-DHADPVAEAREMSSAIQRTPMPLNGQMFKFVLFQTGHDEFYLFGCCH 137 Query: 1227 HIVIDGWSLPILLQEIFAGYF----GHRLPAA--APYRNFVN----WLXXXXXXXXXXXW 1276 HI IDG + ++ + + Y G +P A ++ ++ + W Sbjct: 138 HIAIDGLGMALVCRRVATIYSAMVAGKPIPDAYFGTVQDLIDLESGYEASPDYAEDKAYW 197 Query: 1277 REVLDGFETPTLVAPPGVPGPRGIESYRVSAE----TTRALGELARSQHTTINTVLQAAW 1332 E L E+ + P G R S S + + EL++ +V AA Sbjct: 198 SEHLPP-ESGPVDRLPDAEGERDHYSPSASVQLDPSVANRIKELSKKLAIRRFSVTTAAC 256 Query: 1333 TQLLMRMTGQ-RDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQL 1391 L+ +G +VA VS R ++++ +L VP+ + ++TV D + + Sbjct: 257 ALLVRGWSGSGSEVALDFPVSRRVRP--ESKTLPAMLAGVVPLVLSTAPESTVADFCKHV 314 Query: 1392 QSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREY 1451 + L H+ ++ + G Q + + + P + + + N+ Sbjct: 315 DKRIRELLAHQRFPVHTLEG-DGLRQAPNRVGI-NFIPSRLTLDLAGSPATASYTNHGPV 372 Query: 1452 NHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVD 1511 H+ L + G +L L F + L R Q++L AM +DP R LSS++++ Sbjct: 373 GHFGLFFLGA-GDQLFLSTAGPGQPFASFGVADLAGRLQQILAAMTEDPDRPLSSIELLT 431 Query: 1512 DDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAAN 1571 DE +D W+NR LT+P +P SIP+ FA V+R P+A AVTF SL Y +LDEA+N Sbjct: 432 GDEPALIDRWSNRPALTEPAPAPVSIPQAFAEHVQRTPDAVAVTFGATSLTYAQLDEASN 491 Query: 1572 QLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDA 1631 +L +LLA +G PG VA+M PR ADAIV++LAVLKTGAAY+PIDP+ ++R++F+L DA Sbjct: 492 RLGHLLADHGVGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVPIDPAHASSRMDFVLADA 551 Query: 1632 KPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPK 1691 P A +TT DLRSR D DL V++V DPAVE P T L P+P++ AY+IYTSGTTG PK Sbjct: 552 APSAVITTSDLRSRLDDHDLLVIDVHDPAVEAQPGTALPWPAPENTAYIIYTSGTTGTPK 611 Query: 1692 GVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESI 1751 GVAI H NVT ++++L A LP PG VW+Q HS FD SVWEI+GALL G RL++VPES+ Sbjct: 612 GVAIPHLNVTWLIESLDAGLP--PGNVWTQCHSSAFDFSVWEIFGALLRGRRLLVVPESV 669 Query: 1752 AGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAV-DRV 1810 A SP+D HALLV+E V+VL QTPSAV M+SPEGLE TALVVAGEACPT+VVDRWA RV Sbjct: 670 ASSPEDFHALLVAEQVSVLTQTPSAVAMLSPEGLESTALVVAGEACPTDVVDRWAAPGRV 729 Query: 1811 MINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAX 1870 M++AYGPTE+T+ A+IS PL+ G VVPIGSP+ A FVLD+WL+PVP GVVGELYLA Sbjct: 730 MLDAYGPTETTVCASISTPLTAGDPVVPIGSPIAGAAMFVLDKWLQPVPAGVVGELYLAG 789 Query: 1871 XXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGY 1930 LT +RFV PFG PG+RMYRTGDLV WG DGQLQYLGRADEQVKIRG+ Sbjct: 790 RGVGHGYVRRPGLTASRFVPNPFGAPGSRMYRTGDLVCWGPDGQLQYLGRADEQVKIRGF 849 Query: 1931 RIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMV 1990 RIELGEIQ+ L+ +DGV+QA V+AREDRPGDKRLVGYITGTADPA R++L +RLP YMV Sbjct: 850 RIELGEIQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGTADPAELRAQLADRLPPYMV 909 Query: 1991 PAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXX 2050 P AV+ L+ LPLT NGKLD+RALP+PEY +A YRAP E+ LA I+A VLGVER Sbjct: 910 PTAVMVLDALPLTGNGKLDKRALPSPEY-AAGEYRAPGDAIEEILADIYAQVLGVERVGV 968 Query: 2051 XXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +M+V A A R +F TVA+L+ Sbjct: 969 DDSFFDLGGDSILSMQVVARARAA-GVICRPRDVFVEQTVARLA 1011 >tr|Q9XCF3|Q9XCF3_MYCAV Tax_Id=1764 (pstA)SubName: Full=PstA;[Mycobacterium avium] Length = 3415 Score = 2555 bits (6622), Expect = 0.0 Identities = 1322/2115 (62%), Positives = 1589/2115 (75%), Gaps = 39/2115 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L S +LL DE I+ W NR LT+P P PV+IP FAE V R PDAVA+ Sbjct: 416 MTEDPD-RPLSSIELLTGDEPALIDRWSNRPALTEPAPAPVSIPQAFAEHVQRTPDAVAV 474 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G S TY +LDEASNRL H+LA+HG PG VA + PR +AI+S+L+VLKTGAAY+P Sbjct: 475 TFGATSLTYAQLDEASNRLGHLLADHGVGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVP 534 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAH +R+ F+++DA P A +TT+DLRSRLD +DL V+D+ DPA++ +P AL P P Sbjct: 535 IDPAHASSRMDFVLADAAPSAVITTSDLRSRLDDHDLLVVDVHDPAVEAQPGTALPWPAP 594 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 ++ AY+ YTSGTTG PK VA+ H NVT L+ +L A LP PG VW+Q HS FD SVWEI Sbjct: 595 ENTAYIIYTSGTTGTPKGVAIPHLNVTWLIESLDAGLP--PGNVWTQCHSSAFDFSVWEI 652 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALL G RL+VVPESV SSP+D H LL+ E+VSVL QTPSA MLSPEGLEST L+VAG Sbjct: 653 FGALLRGRRLLVVPESVASSPEDFHALLVAEQVSVLTQTPSAVAMLSPEGLESTALVVAG 712 Query: 301 EACPTELVDRWA-PGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 EACPT++VDRWA PGRVM++AYGPTE T+ A++S PL +FVLDK Sbjct: 713 EACPTDVVDRWAAPGRVMLDAYGPTETTVCASISTPLTAGDPVVPIGSPIAGAAMFVLDK 772 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WL+P P GVVGELY+AG GV GY+ RP LTASRFV PFG G RMYRTGDLV WG DG Sbjct: 773 WLQPVPAGVVGELYLAGRGVGHGYVRRPGLTASRFVPNPFGAPGSRMYRTGDLVCWGPDG 832 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVKIRG+RIELGEIQ+ LA LDGV+QA V+AREDRPGDKRLVGYITGTAD Sbjct: 833 QLQYLGRADEQVKIRGFRIELGEIQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGTAD 892 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA+LR LA+ LP YMVPTAV+VLD +PLT NGKLD+RALP+PEY AA +YRAP E Sbjct: 893 PAELRAQLADRLPPYMVPTAVMVLDALPLTGNGKLDKRALPSPEY--AAGEYRAPGDAIE 950 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 +ILAD+YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+FVEQT Sbjct: 951 EILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVICRPRDVFVEQTVARL 1010 Query: 600 XXXXXXXXESHV--VDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVV 657 + + DEG+GPV TPIMRWL+++DGP +FNQT++ APAGV DDV V Sbjct: 1011 ARVSQVAVDGELGAADEGIGPVRPTPIMRWLQDIDGPIDEFNQTMVLAAPAGVGVDDVAV 1070 Query: 658 ILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRL 717 +LQALLDRH LRLRV+D + WSL PE G+V A +CLR VD+L+D LVEAR+RL Sbjct: 1071 VLQALLDRHPMLRLRVQD--DGAGGWSLEAPEVGSVRAADCLRAVDSLSDAALVEARSRL 1128 Query: 718 DPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGT 777 + + G ++SAVW ETSQL L++HHLAVDGVSWR L+ED+NIAWAQH GQ I LP GT Sbjct: 1129 NVSDGVLLSAVWASETSQLALVVHHLAVDGVSWRTLIEDINIAWAQHQGGQEIALPVPGT 1188 Query: 778 SFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETT 837 SFARWS++LAE+AK+ V A AW+ V + P LP V PD DTY +AGQLSASLDVETT Sbjct: 1189 SFARWSSILAEYAKSPAVVAAAAAWQQVVATPAVLPAVGPD-DTYASAGQLSASLDVETT 1247 Query: 838 RQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRT 897 R LLGEVPAAF AGVQDILL+AFGLA TEF+ PIG+DVEGHGR++E+AS VDLSRT Sbjct: 1248 RLLLGEVPAAFHAGVQDILLIAFGLACTEFVG-GGAPIGIDVEGHGRHEEIASGVDLSRT 1306 Query: 898 VGWFTTKYPVALTV-ENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEV 956 VGWFTTKYPVAL + L W +VVAG+AALG ++K KEQLR+LP+GL+YGLLRYLNPE+ Sbjct: 1307 VGWFTTKYPVALRMGRRLDWARVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEI 1366 Query: 957 DLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTI 1016 ++ G DP IGFNYLGRLGAGA +LSEE+WR+ VPMPL HTVELNAGT+ Sbjct: 1367 EVQGPDPVIGFNYLGRLGAGA-DLSEEMWRVSADSLSSAAVATAVPMPLAHTVELNAGTM 1425 Query: 1017 DTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLT 1076 DTD GP L A+W WA S +EQ RLSRLWFEAL GICAHV+ GGGLTPSD+APARL Sbjct: 1426 DTDAGPQLHANWRWARSVLTDEQLNRLSRLWFEALTGICAHVQAAGGGLTPSDIAPARLD 1485 Query: 1077 QRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRD 1136 Q+QIDEL Q++ + DVLPL+PVQQGLLFH+ FA+ + +D+YAVQL IT++G LD HRLRD Sbjct: 1486 QQQIDELCQQHQIADVLPLSPVQQGLLFHTGFAQEL-EDLYAVQLGITVSGTLDPHRLRD 1544 Query: 1137 AVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERS 1196 AV V RHPNL ARF ++FGEPVQ++ A+P +AWRYL+L G D+ D ++EQL A ER+ Sbjct: 1545 AVQNAVNRHPNLVARFFDEFGEPVQIIPAEPEMAWRYLELDGGDI--DGQLEQLSADERA 1602 Query: 1197 AVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP 1256 AVCDL +P FRAALIR + ++HR +LT HHIVIDGWSLP+LLQE+FAGY+G RLPA Sbjct: 1603 AVCDLAGQPAFRAALIRIADDRHRLLLTIHHIVIDGWSLPVLLQEVFAGYYGQRLPAPPS 1662 Query: 1257 YRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGEL 1316 YR+++ WL WRE L GFETPTLVAPPG G R + +Y VSA+TT+ALGEL Sbjct: 1663 YRSYLMWLSAQDRAAAQDAWREALAGFETPTLVAPPGKIGRRAVATYTVSADTTKALGEL 1722 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA 1376 ARS TT++TVLQ AW QLL +TGQ DVAFGTAVSGRP +L GA++MVGLLINTVP+RA Sbjct: 1723 ARSSRTTVSTVLQGAWAQLLTWLTGQHDVAFGTAVSGRPTELPGADAMVGLLINTVPVRA 1782 Query: 1377 KVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFM 1436 ++A TTV DLL QLQ H DTLEHEHLALN+IH V+GH+QLFDTLFLYE+YPID SA + Sbjct: 1783 DIAAATTVVDLLEQLQRAHADTLEHEHLALNEIHRVTGHDQLFDTLFLYENYPIDASALL 1842 Query: 1437 GVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAM 1496 V ELAVTEF++RE+NHYPLSV+A PGHEL LRVEYDT VFD + IETLI+R +++L AM Sbjct: 1843 DVHELAVTEFSSREFNHYPLSVVATPGHELSLRVEYDTEVFDEAGIETLIERLRQVLAAM 1902 Query: 1497 IDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTF 1556 DP +RLS++D++D E +LD W NRAVLT+ + SIP +FA QV R +A A+T Sbjct: 1903 TTDPGQRLSAIDLLDAAEHERLDAWGNRAVLTRRPAAQASIPALFAAQVARAADAVAITC 1962 Query: 1557 EGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPID 1616 S Y E++E+AN+LA+LL+ GA PG+ VA+++PRSA+A+VAI AVLKTGAAY+PID Sbjct: 1963 GERSFTYREVEESANRLAHLLSGQGAGPGQRVAVVIPRSAEAVVAIFAVLKTGAAYVPID 2022 Query: 1617 PSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDD 1676 P VPAARL+F+L D+ PVAAVTT ++R R DGF Q+++ DDPAV P+T L P+ D+ Sbjct: 2023 PGVPAARLQFVLADSAPVAAVTTAEVRDRLDGFTGQIIDFDDPAVAEQPATGLPVPAADN 2082 Query: 1677 IAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWG 1736 IAY+IYTSGTTG PKGVAI H NVT +L+TL A+L G G VW+Q HSL FD SVWE++G Sbjct: 2083 IAYIIYTSGTTGTPKGVAIPHRNVTLLLETLDAQL--GLGQVWTQCHSLAFDFSVWEVFG 2140 Query: 1737 ALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA------VRMMSPE---GLEG 1787 +LL+GGRLV+VP+++ S +DLHALLV E V+VL QTPSA ++PE L+ Sbjct: 2141 SLLYGGRLVVVPDAVVRSAEDLHALLVREQVSVLSQTPSAFYALQSADALAPELGQQLKL 2200 Query: 1788 TALVVAGEACPTEVVDRWAVDRV----MINAYGPTESTIYAAISAPLSPGSDVVPIGSPV 1843 +V GEA + W MIN YG TE+T++A+ + +DV SP+ Sbjct: 2201 QTVVFGGEALEPHRLATWLHHHPGLPRMINMYGITETTVHASFREIVD--ADVDSSDSPI 2258 Query: 1844 PKGAT----FVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGAR 1899 + A FVLD WLRPVP GVVGELY+A L+ TRFVACPFG PGAR Sbjct: 2259 RRAAANLAFFVLDGWLRPVPVGVVGELYVAGGGLATGYVGRPGLSATRFVACPFGGPGAR 2318 Query: 1900 MYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRP 1959 MYRTGDLVRWG DGQLQY+GRAD QVKIRGYRIELGEIQAAL+ +DGV+ A VIAREDRP Sbjct: 2319 MYRTGDLVRWGADGQLQYMGRADAQVKIRGYRIELGEIQAALAGLDGVEHAAVIAREDRP 2378 Query: 1960 GDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ 2019 GDKRLVGYITGTADPA R++L RLP YMVP+AVV L+ LPLTVNGKLD RALPAPEY Sbjct: 2379 GDKRLVGYITGTADPAEVRAQLGERLPGYMVPSAVVVLDALPLTVNGKLDTRALPAPEYS 2438 Query: 2020 SAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADL 2079 RYRAP T E+ LA I+A VLGVER +M+V A A Sbjct: 2439 DVDRYRAPVTAIEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GVIC 2497 Query: 2080 SVRTLFEAPTVAKLS 2094 R +F TVA+L+ Sbjct: 2498 RPRDVFTEQTVARLA 2512 Score = 1862 bits (4823), Expect = 0.0 Identities = 966/1520 (63%), Positives = 1149/1520 (75%), Gaps = 32/1520 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L + DLLD EH++++ WGNRAVLT +IPALFA QV RA DAVA+ Sbjct: 1902 MTTDPGQR-LSAIDLLDAAEHERLDAWGNRAVLTRRPAAQASIPALFAAQVARAADAVAI 1960 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G+RS+TYRE++E++NRLAH+L+ GA PG VA +IPRS EA+++I +VLKTGAAY+P Sbjct: 1961 TCGERSFTYREVEESANRLAHLLSGQGAGPGQRVAVVIPRSAEAVVAIFAVLKTGAAYVP 2020 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP P AR+ F+++D+ PVAA+TTA++R RLD + +ID DPA+ +P+ L P Sbjct: 2021 IDPGVPAARLQFVLADSAPVAAVTTAEVRDRLDGFTGQIIDFDDPAVAEQPATGLPVPAA 2080 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D++AY+ YTSGTTG PK VA+ H NVT L+ L A L G GQVW+Q HSL FD SVWE+ Sbjct: 2081 DNIAYIIYTSGTTGTPKGVAIPHRNVTLLLETLDAQL--GLGQVWTQCHSLAFDFSVWEV 2138 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPE---GL 291 +G+LL+GGRLVVVP++V S +DLH LL+ E+VSVL QTPSA A L+PE L Sbjct: 2139 FGSLLYGGRLVVVPDAVVRSAEDLHALLVREQVSVLSQTPSAFYALQSADALAPELGQQL 2198 Query: 292 ESTTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSEPLXXXXXXXXXXX 347 + T++ GEA + W PG MIN YG TE T++A+ E + Sbjct: 2199 KLQTVVFGGEALEPHRLATWLHHHPGLPRMINMYGITETTVHASFREIVDADVDSSDSPI 2258 Query: 348 XXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 L FVLD WLRP P GVVGELYVAG G+ATGY+GRP L+A+RFVACPFG G R Sbjct: 2259 RRAAANLAFFVLDGWLRPVPVGVVGELYVAGGGLATGYVGRPGLSATRFVACPFGGPGAR 2318 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLVRWG+DGQL+Y+GRAD QVKIRGYRIELGEIQAALA LDGV+ A VIAREDRP Sbjct: 2319 MYRTGDLVRWGADGQLQYMGRADAQVKIRGYRIELGEIQAALAGLDGVEHAAVIAREDRP 2378 Query: 466 GDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 GDKRLVGYITGTADPA++R L E LP YMVP+AVVVLD +PLTVNGKLD RALPAPEY Sbjct: 2379 GDKRLVGYITGTADPAEVRAQLGERLPGYMVPSAVVVLDALPLTVNGKLDTRALPAPEY- 2437 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQC 585 S + YRAP T E+ILAD+YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ C Sbjct: 2438 SDVDRYRAPVTAIEEILADIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVIC 2497 Query: 586 RPRDIFVEQTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVIT 644 RPRD+F EQT + VVDEG G VVATPIMRWL+ +DGP QFNQT++ Sbjct: 2498 RPRDVFTEQTVARLARVATVATGDDDVVDEGTGRVVATPIMRWLQNMDGPVEQFNQTMVL 2557 Query: 645 QAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA 704 APAGVT DDV +LQALLDRHA LRLRVED + WSL VPEAG+V A +CL TVDA Sbjct: 2558 AAPAGVTPDDVAAVLQALLDRHAMLRLRVED--DGAGGWSLEVPEAGSVQAADCLETVDA 2615 Query: 705 LTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 L+ LV+AR+RL+ A G +V AVW ETSQL L+IHHLAVDGVSWR L+EDLNIAWAQH Sbjct: 2616 LSPAALVDARSRLNLADGILVRAVWASETSQLALIIHHLAVDGVSWRTLIEDLNIAWAQH 2675 Query: 765 CTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVT 824 +GQ + LP GG SFARWSALL +HA+ V + A+ WR V +VP LP QP DTY T Sbjct: 2676 HSGQPVALPTGGMSFARWSALLEDHARRPEVVERAEDWRQVAAVPAVLPGAQPG-DTYAT 2734 Query: 825 AGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGR 884 AGQLSASLDVETTR LLGEVPAAF AGVQDILL+AFGLAWT+F+ + PIG+DVEGHGR Sbjct: 2735 AGQLSASLDVETTRLLLGEVPAAFHAGVQDILLIAFGLAWTQFIG-TGAPIGIDVEGHGR 2793 Query: 885 YDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGL 944 +EL VDLSRTVGWFT KYPVAL + L W QVV GD ALG +VK KEQLR+LP+GL Sbjct: 2794 SEELGPQVDLSRTVGWFTAKYPVALRLGGLSWGQVVGGDEALGAVVKEAKEQLRALPDGL 2853 Query: 945 TYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMP 1004 TYGLLRYLNP+ L SDP I FNYLGRLG GA ELS ELWR+ V +P Sbjct: 2854 TYGLLRYLNPQAGLDVSDPAIAFNYLGRLGGGAAELSPELWRLSPDSFALAGAAGAVELP 2913 Query: 1005 LMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGG 1064 L HTVELNAGT+DT++GP L+A+WTWA SA D++Q RLS LWF+ALAGIC HVR GGGG Sbjct: 2914 LPHTVELNAGTMDTEDGPHLQANWTWARSALDDKQIGRLSELWFDALAGICTHVRAGGGG 2973 Query: 1065 LTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGI--GDDVYAVQLD 1122 LTPSDVA ARLTQR +DEL+QRY V DVLPLTP+QQGLLFH+ A+G +D+YAVQLD Sbjct: 2974 LTPSDVAAARLTQRDLDELAQRYRVADVLPLTPLQQGLLFHAGTAQGSQESEDLYAVQLD 3033 Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDL-RGDDL 1181 I++TG +D RLR+AV TV+ RHPN+ A F E FGEPVQ+L+A+P +AW+Y++L G DL Sbjct: 3034 ISVTGAVDPDRLREAVRTVITRHPNVVAHFSEDFGEPVQILSAEPELAWQYVELDAGADL 3093 Query: 1182 TPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQE 1241 D ++E+L +AER AV DL + P FR ALIRT+ + +RFVLT HHIV+DGWS P+LLQE Sbjct: 3094 --DEQVERLSSAERVAVGDLAQ-PPFRGALIRTAEDAYRFVLTNHHIVLDGWSKPLLLQE 3150 Query: 1242 IFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG--VPGPRG 1299 IFA YFG RLPA PYRNF+ WL WREVL GF+TPTLV P G GPRG Sbjct: 3151 IFAAYFGVRLPAPVPYRNFITWLSAQDRAAAQAAWREVLAGFDTPTLVGPSGRMALGPRG 3210 Query: 1300 IESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLA 1359 + + V A+T+R LGELARS TT++TVLQAAW QLLM +TGQ DV FGTAVSGRP +LA Sbjct: 3211 VAEFHVPADTSRLLGELARSCRTTVSTVLQAAWAQLLMWLTGQHDVVFGTAVSGRPTELA 3270 Query: 1360 GAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLF 1419 G+ESMVGLLINTVP+RA + A+TT+ DLL QLQ + TLEH+HLALNDIH V+GH+Q+F Sbjct: 3271 GSESMVGLLINTVPVRATIGAETTIADLLDQLQRAYTHTLEHQHLALNDIHRVTGHDQIF 3330 Query: 1420 DTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDV 1479 DT+F+YE+YPIDT+A V EL +T F NREYNHYPLSV A+PGHE+GLRVE+DT VF Sbjct: 3331 DTMFVYENYPIDTAALSAVDELTITGFTNREYNHYPLSVQAVPGHEIGLRVEFDTDVFGE 3390 Query: 1480 SEIETLIDRFQRLLEAMIDD 1499 + IE LI+RF+R+LEAM D Sbjct: 3391 ARIEKLIERFRRVLEAMTVD 3410 Score = 724 bits (1870), Expect = 0.0 Identities = 445/1004 (44%), Positives = 590/1004 (58%), Gaps = 36/1004 (3%) Query: 1111 GIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIA 1170 G + + L + I G + + L A+ VA F E G+ VQ I Sbjct: 24 GFAGTQWQLGLLVKIDGKVHRDALEQAITQAVAEAEPGRVSFFEVDGQVVQ-----KPID 78 Query: 1171 WRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPT----FRAALIRTSGNQHRFVLTFH 1226 + +++L DLT DH A E S+ P F+ L +T ++ H Sbjct: 79 YPHVELAFHDLT-DHADPVAEAREMSSAIQRTPMPLNGQMFKFVLFQTGHDEFYLFGCCH 137 Query: 1227 HIVIDGWSLPILLQEIFAGYF----GHRLPAA--APYRNFVN----WLXXXXXXXXXXXW 1276 HI IDG + ++ + + Y G +P A ++ ++ + W Sbjct: 138 HIAIDGLGMALVCRRVATIYSAMVAGKPIPDAYFGTVQDLIDLESGYEASPDYAEDKAYW 197 Query: 1277 REVLDGFETPTLVAPPGVPGPRGIESYRVSAE----TTRALGELARSQHTTINTVLQAAW 1332 E L E+ + P G R S S + + EL++ +V AA Sbjct: 198 SEHLPP-ESGPVDRLPDAEGERDHYSPSASVQLDPSVANRIKELSKKLAIRRFSVTTAAC 256 Query: 1333 TQLLMRMTGQ-RDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQL 1391 L+ +G +VA VS R ++++ +L VP+ + ++TV D + + Sbjct: 257 ALLVRGWSGSGSEVALDFPVSRRVRP--ESKTLPAMLAGVVPLVLSTAPESTVADFCKHV 314 Query: 1392 QSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREY 1451 + L H+ ++ + G Q + + + P + + + N+ Sbjct: 315 DKRIRELLAHQRFPVHTLEG-DGLRQAPNRVGI-NFIPSRLTLDLAGSPATASYTNHGPV 372 Query: 1452 NHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVD 1511 H+ L + G +L L F + L R Q++L AM +DP R LSS++++ Sbjct: 373 GHFGLFFLGA-GDQLFLSTAGPGQPFASFGVADLAGRLQQILAAMTEDPDRPLSSIELLT 431 Query: 1512 DDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAAN 1571 DE +D W+NR LT+P +P SIP+ FA V+R P+A AVTF SL Y +LDEA+N Sbjct: 432 GDEPALIDRWSNRPALTEPAPAPVSIPQAFAEHVQRTPDAVAVTFGATSLTYAQLDEASN 491 Query: 1572 QLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDA 1631 +L +LLA +G PG VA+M PR ADAIV++LAVLKTGAAY+PIDP+ ++R++F+L DA Sbjct: 492 RLGHLLADHGVGPGDCVAVMFPRCADAIVSMLAVLKTGAAYVPIDPAHASSRMDFVLADA 551 Query: 1632 KPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPK 1691 P A +TT DLRSR D DL VV+V DPAVE P T L P+P++ AY+IYTSGTTG PK Sbjct: 552 APSAVITTSDLRSRLDDHDLLVVDVHDPAVEAQPGTALPWPAPENTAYIIYTSGTTGTPK 611 Query: 1692 GVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESI 1751 GVAI H NVT ++++L A LP PG VW+Q HS FD SVWEI+GALL G RL++VPES+ Sbjct: 612 GVAIPHLNVTWLIESLDAGLP--PGNVWTQCHSSAFDFSVWEIFGALLRGRRLLVVPESV 669 Query: 1752 AGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAV-DRV 1810 A SP+D HALLV+E V+VL QTPSAV M+SPEGLE TALVVAGEACPT+VVDRWA RV Sbjct: 670 ASSPEDFHALLVAEQVSVLTQTPSAVAMLSPEGLESTALVVAGEACPTDVVDRWAAPGRV 729 Query: 1811 MINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAX 1870 M++AYGPTE+T+ A+IS PL+ G VVPIGSP+ A FVLD+WL+PVP GVVGELYLA Sbjct: 730 MLDAYGPTETTVCASISTPLTAGDPVVPIGSPIAGAAMFVLDKWLQPVPAGVVGELYLAG 789 Query: 1871 XXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGY 1930 LT +RFV PFG PG+RMYRTGDLV WG DGQLQYLGRADEQVKIRG+ Sbjct: 790 RGVGHGYVRRPGLTASRFVPNPFGAPGSRMYRTGDLVCWGPDGQLQYLGRADEQVKIRGF 849 Query: 1931 RIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMV 1990 RIELGEIQ+ L+ +DGV+QA V+AREDRPGDKRLVGYITGTADPA R++L +RLP YMV Sbjct: 850 RIELGEIQSVLAGLDGVEQAAVVAREDRPGDKRLVGYITGTADPAELRAQLADRLPPYMV 909 Query: 1991 PAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXX 2050 P AV+ L+ LPLT NGKLD+RALP+PEY +A YRAP E+ LA I+A VLGVER Sbjct: 910 PTAVMVLDALPLTGNGKLDKRALPSPEY-AAGEYRAPGDAIEEILADIYAQVLGVERVGV 968 Query: 2051 XXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +M+V A A R +F TVA+L+ Sbjct: 969 DDSFFDLGGDSILSMQVVARARAA-GVICRPRDVFVEQTVARLA 1011 >tr|B1MIF1|B1MIF1_MYCA9 Tax_Id=561007 SubName: Full=Probable non-ribosomal peptide synthetase;[Mycobacterium abscessus] Length = 3454 Score = 2548 bits (6604), Expect = 0.0 Identities = 1338/2148 (62%), Positives = 1572/2148 (73%), Gaps = 58/2148 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P R L S D L DE + GNRA+LT P PV+IP LF QV PDAVAL Sbjct: 422 MAADPDRR-LSSLDSLVNDELADLAELGNRAILTAPAARPVSIPELFTAQVSAEPDAVAL 480 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G S TYRELDEA++RLA L G PG V RS A++ IL+VLKTGAAYLP Sbjct: 481 TFGGSSLTYRELDEAADRLAIQLGHRGVGPGDRVILFSDRSARAVIGILAVLKTGAAYLP 540 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSG--- 177 VDPA P +R+ F++SDA PVAA+TT DLR RLD + LAVID+ A P++ SG Sbjct: 541 VDPAVPASRLEFIVSDAAPVAAITTTDLRGRLDGFGLAVIDL--DAHTDSPAEGQSGLVP 598 Query: 178 --PRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDV 235 P PDD+AY+ YTSGTTG PK VAVTHHNVTQL+ +L A LP PG VW HSL FDV Sbjct: 599 AAPAPDDIAYIIYTSGTTGAPKGVAVTHHNVTQLMQSLDAGLPK-PG-VWPLCHSLAFDV 656 Query: 236 SVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTT 295 SVWEIWGALL GGRL VVPES+ +SP D H+LL+ E+V+VL QTPSA MLSP+GLEST Sbjct: 657 SVWEIWGALLRGGRLAVVPESITASPADFHDLLVAEQVTVLTQTPSAVAMLSPDGLESTA 716 Query: 296 LIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX-- 353 L V GEACP +VD+WAPGR MINAYGPTE T+ A+S PL Sbjct: 717 LAVVGEACPAAVVDKWAPGRTMINAYGPTETTMCVAISAPLKADLPDAVVPIGSPVPGAA 776 Query: 354 LFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLV 413 LFVLD WL+P P GVVGELYVAG GVA GY+GR DLTASRFVACPFG+ G RMYRTGDLV Sbjct: 777 LFVLDTWLQPVPAGVVGELYVAGDGVACGYVGRSDLTASRFVACPFGKPGTRMYRTGDLV 836 Query: 414 RWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGY 473 WG DGQL+YLGRADEQVKIRGYRIELGE+QAAL LDGVDQA I REDRPGDKRLVGY Sbjct: 837 LWGDDGQLQYLGRADEQVKIRGYRIELGEVQAALGALDGVDQAAAIVREDRPGDKRLVGY 896 Query: 474 ITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRA 533 +TGTADPA++R L++ LP YMVP AVVVL+T+PLT N KLD RALPAPEY DYRA Sbjct: 897 VTGTADPAEIRGILSKRLPPYMVPAAVVVLETLPLTSNNKLDTRALPAPEYGGLGADYRA 956 Query: 534 PSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVE 593 P E+ILA VYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+F+E Sbjct: 957 PGNAVEEILAGVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVLCRPRDVFIE 1016 Query: 594 QTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTE 652 QT E++V DEG+G V TPIM WLR+VDGP +FNQT++ Q P+ VT+ Sbjct: 1017 QTVSRLAAVAEVSGGEAYVADEGLGTVAVTPIMHWLRDVDGPIVEFNQTLVIQVPSSVTQ 1076 Query: 653 DDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVE 712 DDVV++LQALLDRH +LRLR++D D WSLLVPEAGAV AR+ L V L+D+ LV Sbjct: 1077 DDVVIVLQALLDRHPSLRLRLQDNDGD---WSLLVPEAGAVDARDRLHVVGELSDEALVA 1133 Query: 713 ARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIEL 772 AR LDPA G+M+SAVWV T+QL L+IHHLAVDGVSWRILLED+NIAWAQH G IEL Sbjct: 1134 ARTALDPATGSMLSAVWVPGTAQLALVIHHLAVDGVSWRILLEDINIAWAQHHGGADIEL 1193 Query: 773 PAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASL 832 PAGGTSFARWSALLAEHA + V + AD WR V + P + VQP+ DTY AG+LS +L Sbjct: 1194 PAGGTSFARWSALLAEHALSTDVVEQADTWRQVLATPARVGTVQPEIDTYANAGRLSVAL 1253 Query: 833 DVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDV 892 D ETTRQLLGEVPAAF AGVQDILL+AFGLAW EFL S PI D+EGHGR +E+ V Sbjct: 1254 DTETTRQLLGEVPAAFHAGVQDILLIAFGLAWNEFLGVSGAPIAFDIEGHGRQEEIGEAV 1313 Query: 893 ----DLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGL 948 DLSRT GWFTTKYP +L V L W QV AG+AALG ++K KEQLR+LP+GLTYGL Sbjct: 1314 HRRIDLSRTTGWFTTKYPASLAVGELSWAQVSAGEAALGPVIKTAKEQLRALPDGLTYGL 1373 Query: 949 LRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHT 1008 LRYLNP VDL G +PTIGFNYLGRLGAGAG+LSE+ WRI + MPL H+ Sbjct: 1374 LRYLNPGVDLTGPEPTIGFNYLGRLGAGAGDLSEDFWRISADSLRLTDVAAAISMPLAHS 1433 Query: 1009 VELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPS 1068 VELNAGT+DT GP LRA+W+WAPSA D QA RLSRLWFEALAGICAHVR GGGGLTPS Sbjct: 1434 VELNAGTMDTAAGPELRANWSWAPSALDGAQADRLSRLWFEALAGICAHVRSGGGGLTPS 1493 Query: 1069 DVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGD----DVYAVQLDIT 1124 D+APARL Q QID L Q+YD++DVLPLTP+QQGLLF + FA GD DVYAVQL +T Sbjct: 1494 DLAPARLNQPQIDALVQQYDISDVLPLTPLQQGLLFQAGFAEATGDSTEDDVYAVQLALT 1553 Query: 1125 ITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD 1184 +TG LD RL DAV V RHPNL ARF E++GEPVQ++ ADP+IAW++++L GD D Sbjct: 1554 LTGALDVARLHDAVSAVAKRHPNLVARFSEEYGEPVQIILADPVIAWQHVELIGDI---D 1610 Query: 1185 HEIEQLCAAERSAVCDLLERPTFRAALIRTSGN-------QHRFVLTFHHIVIDGWSLPI 1237 ++EQLCAAER+AVC L P FRAALI G +HR VLT HHIVIDGWSLPI Sbjct: 1611 QQVEQLCAAERAAVCRLFTEPVFRAALISGLGGAEDGEVGKHRLVLTAHHIVIDGWSLPI 1670 Query: 1238 LLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGP 1297 LLQEIF+ Y+GH+LPA APYRNFV WL W LDGFE PTLV G Sbjct: 1671 LLQEIFSIYYGHQLPAPAPYRNFVTWLAGQDRVAAQSVWGRALDGFEAPTLVGSLATAGR 1730 Query: 1298 RGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPAD 1357 RG+ESYR+S + TR+LGELAR+QHTT+NTVLQAAW Q+L +TGQ DVAFGTAVSGRPAD Sbjct: 1731 RGVESYRISEDITRSLGELARAQHTTVNTVLQAAWAQVLTWLTGQHDVAFGTAVSGRPAD 1790 Query: 1358 LAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQ 1417 LAGA+SMVGLLINTVP+RA ++A TTV DLL QLQ HNDT+EHEHLALN+IHH G ++ Sbjct: 1791 LAGADSMVGLLINTVPVRANITAATTVADLLDQLQRMHNDTVEHEHLALNEIHHAIGLDR 1850 Query: 1418 LFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVF 1477 LFDTLF+YE+YPID A +G +EL +T+F++REYNHYPLSV+A+PG+EL LRVE+DT VF Sbjct: 1851 LFDTLFVYENYPIDADALLGARELGITDFSSREYNHYPLSVVAMPGNELSLRVEFDTDVF 1910 Query: 1478 DVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSI 1537 D +EI+T++D+ +++L AM DPA RLSS+D++D E +LD+W NRAVL +P + SI Sbjct: 1911 DSAEIDTVVDKLRQVLAAMTVDPATRLSSIDLLDAGEHDRLDKWGNRAVLIRPEPALTSI 1970 Query: 1538 PEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSAD 1597 PE+FA QV R PEA A+T S +YGELD AN+LAN L +GA PG+ VAL++PR+ + Sbjct: 1971 PELFAAQVARAPEAIAITCGERSWSYGELDATANRLANHLVTHGARPGERVALLLPRTGE 2030 Query: 1598 AIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVD 1657 AI AILAVLKTGAAYLPIDP+ P +R++F+LGDA P+ AVTT +L R + V+++D Sbjct: 2031 AIAAILAVLKTGAAYLPIDPAHPDSRVDFVLGDAAPIVAVTTAELLPRLSASGVPVIDID 2090 Query: 1658 DPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGA 1717 DPAV TTL P+ DDIAY+IYTSGTTG PKGVA+TH NV Q+L++L AEL G Sbjct: 2091 DPAVSAQNDTTLPVPAVDDIAYIIYTSGTTGAPKGVAVTHRNVAQLLESLDAELAL--GQ 2148 Query: 1718 VWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA- 1776 VW+Q HSL FD SVWEIWGALL+GGRL++VP+++ SP++LHALLVSE V+VL QTPSA Sbjct: 2149 VWTQCHSLAFDYSVWEIWGALLYGGRLLVVPDAVVRSPEELHALLVSEEVSVLSQTPSAF 2208 Query: 1777 -----VRMMSPE---GLEGTALVVAGEACPTEVVDRWAVDRV----MINAYGPTESTIYA 1824 + PE L+ +V GEA + + W MIN YG TE+T++A Sbjct: 2209 YALQTADALQPEMGQQLKLQTVVFGGEALEPQRLSSWFDSHPGLPRMINMYGITETTVHA 2268 Query: 1825 AISAPLSPG---SDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXX 1881 + + G S+ PIG P+ A FVLD WLR VP GVVGELY+A Sbjct: 2269 SF-REIDDGDVDSNSSPIGVPLEHLAFFVLDGWLRKVPVGVVGELYVAGSGQASGYLGRS 2327 Query: 1882 XLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAAL 1941 LT TRFVACPFG PG+RMYRTGDLV+WG+DGQL+Y+GRAD+QVKIRGYRIELGE+ AAL Sbjct: 2328 DLTTTRFVACPFGAPGSRMYRTGDLVQWGEDGQLRYVGRADKQVKIRGYRIELGEVHAAL 2387 Query: 1942 SDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTNRLPAYMVPAAVVTL 1997 + V GVDQA VIAREDRPGDKRLVGYIT GT DP A R+ L RLP+YMVPAAVV L Sbjct: 2388 ARVAGVDQAAVIAREDRPGDKRLVGYITESTAGTLDPTAVRATLAERLPSYMVPAAVVVL 2447 Query: 1998 ETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXX 2057 + LPLTVNGKLD RALPAPE+Q A YRAPE E+ LAGI+A VLGVE+ Sbjct: 2448 DALPLTVNGKLDTRALPAPEFQDADHYRAPEDAVEEILAGIYAQVLGVEQIGVDDSFFDL 2507 Query: 2058 XXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERT 2105 +M+V A A L R +F TV++L+ GE T Sbjct: 2508 GGDSISSMQVVARARAA-GLLLRPRDIFVEQTVSRLAQVAVFADGEAT 2554 Score = 1862 bits (4824), Expect = 0.0 Identities = 951/1525 (62%), Positives = 1143/1525 (74%), Gaps = 34/1525 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P+TR L S DLLD EHD+++ WGNRAVL P P +IP LFA QV RAP+A+A+ Sbjct: 1929 MTVDPATR-LSSIDLLDAGEHDRLDKWGNRAVLIRPEPALTSIPELFAAQVARAPEAIAI 1987 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G+RSW+Y ELD +NRLA+ L HGA+PG VA L+PR+GEAI +IL+VLKTGAAYLP Sbjct: 1988 TCGERSWSYGELDATANRLANHLVTHGARPGERVALLLPRTGEAIAAILAVLKTGAAYLP 2047 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAHPD+R+ F++ DA P+ A+TTA+L RL + VID+ DPA+ + L P Sbjct: 2048 IDPAHPDSRVDFVLGDAAPIVAVTTAELLPRLSASGVPVIDIDDPAVSAQNDTTLPVPAV 2107 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH NV QL+ +L A+L G QVW+Q HSL FD SVWEI Sbjct: 2108 DDIAYIIYTSGTTGAPKGVAVTHRNVAQLLESLDAELALG--QVWTQCHSLAFDYSVWEI 2165 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPE---GL 291 WGALL+GGRL+VVP++V SP++LH LL++E+VSVL QTPSA A L PE L Sbjct: 2166 WGALLYGGRLLVVPDAVVRSPEELHALLVSEEVSVLSQTPSAFYALQTADALQPEMGQQL 2225 Query: 292 ESTTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSEPLXXXXXXXXXXX 347 + T++ GEA + + W PG MIN YG TE T++A+ E Sbjct: 2226 KLQTVVFGGEALEPQRLSSWFDSHPGLPRMINMYGITETTVHASFREIDDGDVDSNSSPI 2285 Query: 348 XXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 L FVLD WLR P GVVGELYVAG G A+GY+GR DLT +RFVACPFG G R Sbjct: 2286 GVPLEHLAFFVLDGWLRKVPVGVVGELYVAGSGQASGYLGRSDLTTTRFVACPFGAPGSR 2345 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLV+WG DGQL Y+GRAD+QVKIRGYRIELGE+ AALA++ GVDQA VIAREDRP Sbjct: 2346 MYRTGDLVQWGEDGQLRYVGRADKQVKIRGYRIELGEVHAALARVAGVDQAAVIAREDRP 2405 Query: 466 GDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPA 521 GDKRLVGYIT GT DP +R LAE LP+YMVP AVVVLD +PLTVNGKLD RALPA Sbjct: 2406 GDKRLVGYITESTAGTLDPTAVRATLAERLPSYMVPAAVVVLDALPLTVNGKLDTRALPA 2465 Query: 522 PEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA 581 PE++ A + YRAP E+ILA +YAQVLGVE++GVDDSFFDLGGDSI SMQVVARARAA Sbjct: 2466 PEFQDA-DHYRAPEDAVEEILAGIYAQVLGVEQIGVDDSFFDLGGDSISSMQVVARARAA 2524 Query: 582 GIQCRPRDIFVEQTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQ 640 G+ RPRDIFVEQT E+ VVD G GPVVATPI+RWL + G G+FNQ Sbjct: 2525 GLLLRPRDIFVEQTVSRLAQVAVFADGEATVVDAGTGPVVATPIIRWLHGLGGNVGEFNQ 2584 Query: 641 TVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR 700 TV+ QAP GV+EDDVV +LQALLDRHATLRLR E E+ EW+LL+PE G V AR CL Sbjct: 2585 TVVLQAPEGVSEDDVVTVLQALLDRHATLRLRAE---ENDGEWALLIPEVGTVDARACLL 2641 Query: 701 TVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIA 760 V+AL+D+ L AR+RL+PA G+M+SA+W ++LVL++HHLAVD VSWRILLED NIA Sbjct: 2642 AVEALSDEALRHARSRLNPATGSMLSALWESGKNRLVLIVHHLAVDAVSWRILLEDFNIA 2701 Query: 761 WAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTD 820 WAQH GQ++ELP+GGTSFARW+ LL E A+T V L D WR V +P ALP V P D Sbjct: 2702 WAQHHGGQAVELPSGGTSFARWATLLDERARTADVEALTDTWRQVEKIPPALPAVHPTMD 2761 Query: 821 TYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVE 880 TY +AGQLS SLD + TR+LLGEVP A+ AGVQDILL+AF LAW EFL + PIG+DVE Sbjct: 2762 TYASAGQLSVSLDADLTRELLGEVPVAYHAGVQDILLIAFALAWNEFLGSAGAPIGIDVE 2821 Query: 881 GHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSL 940 GHGR +E +D DLSRTVGWFT+KYPV+L V L W QVVAGD ALG ++K KEQLR+L Sbjct: 2822 GHGRNEEFVADADLSRTVGWFTSKYPVSLAVGELSWAQVVAGDPALGPVIKGAKEQLRTL 2881 Query: 941 PEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXX 1000 P+GLTYGLLRYLNP+ D+ G DP+IGFNYLGRLGAG +LS++LWRIDQ Sbjct: 2882 PDGLTYGLLRYLNPDADVAGPDPSIGFNYLGRLGAGGVDLSDDLWRIDQDGVAITAAATA 2941 Query: 1001 VPMPLMHTVELNAGTI-DTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVR 1059 VP PL HTVELNAG + D D G L A+WTWA SA Q R+SRLWF++LAGICAHVR Sbjct: 2942 VPTPLGHTVELNAGVMEDADAGARLHATWTWALSALSHNQVDRISRLWFDSLAGICAHVR 3001 Query: 1060 GGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFA-RGI--GDDV 1116 GGGGGL+PSDV PARLTQ+QID+L ++Y++ DVLPLTP+QQGLLFHS A G+ DD+ Sbjct: 3002 GGGGGLSPSDVMPARLTQQQIDQLDEQYEIADVLPLTPLQQGLLFHSNLAPEGLEGSDDL 3061 Query: 1117 YAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDL 1176 YAVQLD+ ++G LD RL+DAVH+ + R PN+ ARF E+FGEPVQ++ ADP +AW+YL+L Sbjct: 3062 YAVQLDVALSGPLDPKRLQDAVHSAIRRRPNVVARFYEEFGEPVQLIPADPELAWQYLEL 3121 Query: 1177 RGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLP 1236 D + ++E+L A+ER+AVCDL +P FRAAL RT +Q+RF++T HHIV+DGWS P Sbjct: 3122 DADS-EAEEQVERLAASERAAVCDLAGQPAFRAALARTGTDQYRFLVTNHHIVLDGWSKP 3180 Query: 1237 ILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG--V 1294 ILLQEIFA YFG RLPA YR FV WL W +V +GFETPTLV PPG V Sbjct: 3181 ILLQEIFASYFGERLPAPVAYRRFVTWLSGQDNDAARSAWGKVFEGFETPTLVGPPGRMV 3240 Query: 1295 PGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR 1354 G RG+ES+ VSAETT+ALGELARS TT++TVLQAAW QLLM +TGQ DVAFGTAVSGR Sbjct: 3241 LGRRGVESFEVSAETTQALGELARSCRTTVSTVLQAAWAQLLMWLTGQTDVAFGTAVSGR 3300 Query: 1355 PADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG 1414 P DL GAESMVGLLINTVP+RA ++ DTT+ LL QLQ+ + +TLEH+HLAL +IHH G Sbjct: 3301 PTDLVGAESMVGLLINTVPVRATITPDTTIASLLNQLQAAYGETLEHQHLALKEIHHAVG 3360 Query: 1415 HEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDT 1474 H+QLFDT+F+YE+YPIDT+A V EL++T F+NREYNHYPL+V A PGHELGLRVE+DT Sbjct: 3361 HDQLFDTMFVYENYPIDTAALSRVHELSITGFSNREYNHYPLAVQATPGHELGLRVEFDT 3420 Query: 1475 SVFDVSEIETLIDRFQRLLEAMIDD 1499 VF+ I L+ RFQR+LEAM D Sbjct: 3421 DVFNAVRIGKLVKRFQRVLEAMTSD 3445 Score = 719 bits (1856), Expect = 0.0 Identities = 455/1007 (45%), Positives = 566/1007 (56%), Gaps = 37/1007 (3%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 + I G +++ L A+ V A F E G+ VQ + + DLR D Sbjct: 37 VRIEGQVERVLLERAIRQAVTEAEPARAAFFEVDGQIVQRPIDHSDLELAFEDLRDSDDP 96 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 ++ +R+ + L + AL RT+ ++ HHI +DG + ++ + + Sbjct: 97 AGLARKKATDIQRTLMP--LTGQLLKFALYRTADDEFHLFGLCHHINLDGLGMAVVSRRV 154 Query: 1243 FAGYF----GHRLPAA--APYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVP- 1295 + Y G +P A ++ V+W RE P +P Sbjct: 155 ASIYTALATGEPIPPAYFGTLQDLVDWETDYVASAEYAEDREYWSNNLPPDSGLDYRMPH 214 Query: 1296 ------GPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMR--MTGQRDVAF 1347 G + +S ++ T + EL + +V+ AA LL+R T +VA Sbjct: 215 ASEESDGYKPSDSVQMDDVTVSEIKELTKVLRIRRYSVITAACA-LLVRGWSTSGSEVAL 273 Query: 1348 GTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALN 1407 VS R + ++ G++ VP+ +TV + R + + + L+H+ Sbjct: 274 DFPVSRRVHP--DSRTLPGMMAGVVPLVLNAPPQSTVAEFCRHVDTRIRELLQHQRFP-- 329 Query: 1408 DIHHVSGHE-QLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMAL----P 1462 +H + E L ++ +LA NH P+ L Sbjct: 330 -VHTLEDEEFGLRGPRHAGNRVAVNFIPARLTLDLAGAPATASYTNHGPMGHFGLFFIGA 388 Query: 1463 GHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWA 1522 +L L D F + L R QRLL M DP RRLSS+D + +DE L E Sbjct: 389 SDQLVLSSSGDGEPFARFGVPNLAVRLQRLLSEMAADPDRRLSSLDSLVNDELADLAELG 448 Query: 1523 NRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGA 1582 NRA+LT P P SIPE+F QV +P+A A+TF G SL Y ELDEAA++LA L G Sbjct: 449 NRAILTAPAARPVSIPELFTAQVSAEPDAVALTFGGSSLTYRELDEAADRLAIQLGHRGV 508 Query: 1583 APGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDL 1642 PG V L RSA A++ ILAVLKTGAAYLP+DP+VPA+RLEF++ DA PVAA+TT DL Sbjct: 509 GPGDRVILFSDRSARAVIGILAVLKTGAAYLPVDPAVPASRLEFIVSDAAPVAAITTTDL 568 Query: 1643 RSRFDGFDLQVVEVD---DPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGN 1699 R R DGF L V+++D D E P+PDDIAY+IYTSGTTG PKGVA+TH N Sbjct: 569 RGRLDGFGLAVIDLDAHTDSPAEGQSGLVPAAPAPDDIAYIIYTSGTTGAPKGVAVTHHN 628 Query: 1700 VTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLH 1759 VTQ++ +L A LP PG VW HSL FDVSVWEIWGALL GGRL +VPESI SP D H Sbjct: 629 VTQLMQSLDAGLPK-PG-VWPLCHSLAFDVSVWEIWGALLRGGRLAVVPESITASPADFH 686 Query: 1760 ALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTE 1819 LLV+E V VL QTPSAV M+SP+GLE TAL V GEACP VVD+WA R MINAYGPTE Sbjct: 687 DLLVAEQVTVLTQTPSAVAMLSPDGLESTALAVVGEACPAAVVDKWAPGRTMINAYGPTE 746 Query: 1820 STIYAAISAPLSPG--SDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXX 1877 +T+ AISAPL VVPIGSPVP A FVLD WL+PVP GVVGELY+A Sbjct: 747 TTMCVAISAPLKADLPDAVVPIGSPVPGAALFVLDTWLQPVPAGVVGELYVAGDGVACGY 806 Query: 1878 XXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEI 1937 LT +RFVACPFG+PG RMYRTGDLV WGDDGQLQYLGRADEQVKIRGYRIELGE+ Sbjct: 807 VGRSDLTASRFVACPFGKPGTRMYRTGDLVLWGDDGQLQYLGRADEQVKIRGYRIELGEV 866 Query: 1938 QAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTL 1997 QAAL +DGVDQA I REDRPGDKRLVGY+TGTADPA R L+ RLP YMVPAAVV L Sbjct: 867 QAALGALDGVDQAAAIVREDRPGDKRLVGYVTGTADPAEIRGILSKRLPPYMVPAAVVVL 926 Query: 1998 ETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXX 2056 ETLPLT N KLD RALPAPEY YRAP E+ LAG++A VLGVER Sbjct: 927 ETLPLTSNNKLDTRALPAPEYGGLGADYRAPGNAVEEILAGVYAQVLGVERVGVDDSFFD 986 Query: 2057 XXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 +M+V A A R +F TV++L+ E GE Sbjct: 987 LGGDSILSMQVVARARAA-GVLCRPRDVFIEQTVSRLAAVAEVSGGE 1032 >tr|A5A9U2|A5A9U2_MYCAB Tax_Id=36809 (mps1)SubName: Full=Mps1 protein;[Mycobacterium abscessus] Length = 3454 Score = 2548 bits (6604), Expect = 0.0 Identities = 1338/2148 (62%), Positives = 1572/2148 (73%), Gaps = 58/2148 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P R L S D L DE + GNRA+LT P PV+IP LF QV PDAVAL Sbjct: 422 MAADPDRR-LSSLDSLVNDELADLAELGNRAILTAPAARPVSIPELFTAQVSAEPDAVAL 480 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G S TYRELDEA++RLA L G PG V RS A++ IL+VLKTGAAYLP Sbjct: 481 TFGGSSLTYRELDEAADRLAIQLGHRGVGPGDRVILFSDRSARAVIGILAVLKTGAAYLP 540 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSG--- 177 VDPA P +R+ F++SDA PVAA+TT DLR RLD + LAVID+ A P++ SG Sbjct: 541 VDPAVPASRLEFIVSDAAPVAAITTTDLRGRLDGFGLAVIDL--DAHTDSPAEGQSGLVP 598 Query: 178 --PRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDV 235 P PDD+AY+ YTSGTTG PK VAVTHHNVTQL+ +L A LP PG VW HSL FDV Sbjct: 599 AAPAPDDIAYIIYTSGTTGAPKGVAVTHHNVTQLMQSLDAGLPK-PG-VWPLCHSLAFDV 656 Query: 236 SVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTT 295 SVWEIWGALL GGRL VVPES+ +SP D H+LL+ E+V+VL QTPSA MLSP+GLEST Sbjct: 657 SVWEIWGALLRGGRLAVVPESITASPADFHDLLVAEQVTVLTQTPSAVAMLSPDGLESTA 716 Query: 296 LIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX-- 353 L V GEACP +VD+WAPGR MINAYGPTE T+ A+S PL Sbjct: 717 LAVVGEACPAAVVDKWAPGRTMINAYGPTETTMCVAISAPLKADLPDAVVPIGSPVPGAA 776 Query: 354 LFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLV 413 LFVLD WL+P P GVVGELYVAG GVA GY+GR DLTASRFVACPFG+ G RMYRTGDLV Sbjct: 777 LFVLDTWLQPVPAGVVGELYVAGDGVACGYVGRSDLTASRFVACPFGKPGTRMYRTGDLV 836 Query: 414 RWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGY 473 WG DGQL+YLGRADEQVKIRGYRIELGE+QAAL LDGVDQA I REDRPGDKRLVGY Sbjct: 837 LWGDDGQLQYLGRADEQVKIRGYRIELGEVQAALGALDGVDQAAAIVREDRPGDKRLVGY 896 Query: 474 ITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRA 533 +TGTADPA++R L++ LP YMVP AVVVL+T+PLT N KLD RALPAPEY DYRA Sbjct: 897 VTGTADPAEIRGILSKRLPPYMVPAAVVVLETLPLTSNNKLDTRALPAPEYGGLGADYRA 956 Query: 534 PSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVE 593 P E+ILA VYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+F+E Sbjct: 957 PGNAVEEILAGVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVLCRPRDVFIE 1016 Query: 594 QTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTE 652 QT E++V DEG+G V TPIM WLR+VDGP +FNQT++ Q P+ VT+ Sbjct: 1017 QTVSRLAAVAEVSGGEAYVADEGLGTVAVTPIMHWLRDVDGPIVEFNQTLVIQVPSSVTQ 1076 Query: 653 DDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVE 712 DDVV++LQALLDRH +LRLR++D D WSLLVPEAGAV AR+ L V L+D+ LV Sbjct: 1077 DDVVIVLQALLDRHPSLRLRLQDNDGD---WSLLVPEAGAVDARDRLHVVGELSDEALVA 1133 Query: 713 ARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIEL 772 AR LDPA G+M+SAVWV T+QL L+IHHLAVDGVSWRILLED+NIAWAQH G IEL Sbjct: 1134 ARTALDPATGSMLSAVWVPGTAQLALVIHHLAVDGVSWRILLEDINIAWAQHHGGADIEL 1193 Query: 773 PAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASL 832 PAGGTSFARWSALLAEHA + V + AD WR V + P + VQP+ DTY AG+LS +L Sbjct: 1194 PAGGTSFARWSALLAEHALSTDVVEQADTWRQVLATPARVGTVQPEIDTYANAGRLSVAL 1253 Query: 833 DVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDV 892 D ETTRQLLGEVPAAF AGVQDILL+AFGLAW EFL S PI D+EGHGR +E+ V Sbjct: 1254 DTETTRQLLGEVPAAFHAGVQDILLIAFGLAWNEFLGVSGAPIAFDIEGHGRQEEIGEAV 1313 Query: 893 ----DLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGL 948 DLSRT GWFTTKYP +L V L W QV AG+AALG ++K KEQLR+LP+GLTYGL Sbjct: 1314 HRRIDLSRTTGWFTTKYPASLAVGELSWAQVSAGEAALGPVIKTAKEQLRALPDGLTYGL 1373 Query: 949 LRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHT 1008 LRYLNP VDL G +PTIGFNYLGRLGAGAG+LSE+ WRI + MPL H+ Sbjct: 1374 LRYLNPGVDLTGPEPTIGFNYLGRLGAGAGDLSEDFWRISADSLRLTDVAAAISMPLAHS 1433 Query: 1009 VELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPS 1068 VELNAGT+DT GP LRA+W+WAPSA D QA RLSRLWFEALAGICAHVR GGGGLTPS Sbjct: 1434 VELNAGTMDTAAGPELRANWSWAPSALDGAQADRLSRLWFEALAGICAHVRSGGGGLTPS 1493 Query: 1069 DVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGD----DVYAVQLDIT 1124 D+APARL Q QID L Q+YD++DVLPLTP+QQGLLF + FA GD DVYAVQL +T Sbjct: 1494 DLAPARLNQPQIDALVQQYDISDVLPLTPLQQGLLFQAGFAEATGDSTEDDVYAVQLALT 1553 Query: 1125 ITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD 1184 +TG LD RL DAV V RHPNL ARF E++GEPVQ++ ADP+IAW++++L GD D Sbjct: 1554 LTGALDVARLHDAVSAVAKRHPNLVARFSEEYGEPVQIILADPVIAWQHVELIGDI---D 1610 Query: 1185 HEIEQLCAAERSAVCDLLERPTFRAALIRTSGN-------QHRFVLTFHHIVIDGWSLPI 1237 ++EQLCAAER+AVC L P FRAALI G +HR VLT HHIVIDGWSLPI Sbjct: 1611 QQVEQLCAAERAAVCRLFTEPVFRAALISGLGGAEDGEVGKHRLVLTAHHIVIDGWSLPI 1670 Query: 1238 LLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGP 1297 LLQEIF+ Y+GH+LPA APYRNFV WL W LDGFE PTLV G Sbjct: 1671 LLQEIFSIYYGHQLPAPAPYRNFVTWLAGQDRVAAQSVWGRALDGFEAPTLVGSLATAGR 1730 Query: 1298 RGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPAD 1357 RG+ESYR+S + TR+LGELAR+QHTT+NTVLQAAW Q+L +TGQ DVAFGTAVSGRPAD Sbjct: 1731 RGVESYRISEDITRSLGELARAQHTTVNTVLQAAWAQVLTWLTGQHDVAFGTAVSGRPAD 1790 Query: 1358 LAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQ 1417 LAGA+SMVGLLINTVP+RA ++A TTV DLL QLQ HNDT+EHEHLALN+IHH G ++ Sbjct: 1791 LAGADSMVGLLINTVPVRANITAATTVADLLDQLQRMHNDTVEHEHLALNEIHHAIGLDR 1850 Query: 1418 LFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVF 1477 LFDTLF+YE+YPID A +G +EL +T+F++REYNHYPLSV+A+PG+EL LRVE+DT VF Sbjct: 1851 LFDTLFVYENYPIDADALLGARELGITDFSSREYNHYPLSVVAMPGNELSLRVEFDTDVF 1910 Query: 1478 DVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSI 1537 D +EI+T++D+ +++L AM DPA RLSS+D++D E +LD+W NRAVL +P + SI Sbjct: 1911 DSAEIDTVVDKLRQVLAAMTVDPATRLSSIDLLDAGEHDRLDKWGNRAVLIRPEPALTSI 1970 Query: 1538 PEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSAD 1597 PE+FA QV R PEA A+T S +YGELD AN+LAN L +GA PG+ VAL++PR+ + Sbjct: 1971 PELFAAQVARAPEAIAITCGERSWSYGELDATANRLANHLVTHGARPGERVALLLPRTGE 2030 Query: 1598 AIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVD 1657 AI AILAVLKTGAAYLPIDP+ P +R++F+LGDA P+ AVTT +L R + V+++D Sbjct: 2031 AIAAILAVLKTGAAYLPIDPAHPDSRVDFVLGDAAPIVAVTTAELLPRLSASGVPVIDID 2090 Query: 1658 DPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGA 1717 DPAV TTL P+ DDIAY+IYTSGTTG PKGVA+TH NV Q+L++L AEL G Sbjct: 2091 DPAVSAQNDTTLPVPAVDDIAYIIYTSGTTGAPKGVAVTHRNVAQLLESLDAELAL--GQ 2148 Query: 1718 VWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA- 1776 VW+Q HSL FD SVWEIWGALL+GGRL++VP+++ SP++LHALLVSE V+VL QTPSA Sbjct: 2149 VWTQCHSLAFDYSVWEIWGALLYGGRLLVVPDAVVRSPEELHALLVSEEVSVLSQTPSAF 2208 Query: 1777 -----VRMMSPE---GLEGTALVVAGEACPTEVVDRWAVDRV----MINAYGPTESTIYA 1824 + PE L+ +V GEA + + W MIN YG TE+T++A Sbjct: 2209 YALQTADALQPEMGQQLKLQTVVFGGEALEPQRLSSWFDSHPGLPRMINMYGITETTVHA 2268 Query: 1825 AISAPLSPG---SDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXX 1881 + + G S+ PIG P+ A FVLD WLR VP GVVGELY+A Sbjct: 2269 SF-REIDDGDVDSNSSPIGVPLEHLAFFVLDGWLRKVPVGVVGELYVAGSGQASGYLGRS 2327 Query: 1882 XLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAAL 1941 LT TRFVACPFG PG+RMYRTGDLV+WG+DGQL+Y+GRAD+QVKIRGYRIELGE+ AAL Sbjct: 2328 DLTTTRFVACPFGAPGSRMYRTGDLVQWGEDGQLRYVGRADKQVKIRGYRIELGEVHAAL 2387 Query: 1942 SDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTNRLPAYMVPAAVVTL 1997 + V GVDQA VIAREDRPGDKRLVGYIT GT DP A R+ L RLP+YMVPAAVV L Sbjct: 2388 ARVAGVDQAAVIAREDRPGDKRLVGYITESTAGTLDPTAVRATLAERLPSYMVPAAVVVL 2447 Query: 1998 ETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXX 2057 + LPLTVNGKLD RALPAPE+Q A YRAPE E+ LAGI+A VLGVE+ Sbjct: 2448 DALPLTVNGKLDTRALPAPEFQDADHYRAPEDAVEEILAGIYAQVLGVEQIGVDDSFFDL 2507 Query: 2058 XXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERT 2105 +M+V A A L R +F TV++L+ GE T Sbjct: 2508 GGDSISSMQVVARARAA-GLLLRPRDIFVEQTVSRLAQVAVFADGEAT 2554 Score = 1862 bits (4824), Expect = 0.0 Identities = 951/1525 (62%), Positives = 1143/1525 (74%), Gaps = 34/1525 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P+TR L S DLLD EHD+++ WGNRAVL P P +IP LFA QV RAP+A+A+ Sbjct: 1929 MTVDPATR-LSSIDLLDAGEHDRLDKWGNRAVLIRPEPALTSIPELFAAQVARAPEAIAI 1987 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G+RSW+Y ELD +NRLA+ L HGA+PG VA L+PR+GEAI +IL+VLKTGAAYLP Sbjct: 1988 TCGERSWSYGELDATANRLANHLVTHGARPGERVALLLPRTGEAIAAILAVLKTGAAYLP 2047 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAHPD+R+ F++ DA P+ A+TTA+L RL + VID+ DPA+ + L P Sbjct: 2048 IDPAHPDSRVDFVLGDAAPIVAVTTAELLPRLSASGVPVIDIDDPAVSAQNDTTLPVPAV 2107 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH NV QL+ +L A+L G QVW+Q HSL FD SVWEI Sbjct: 2108 DDIAYIIYTSGTTGAPKGVAVTHRNVAQLLESLDAELALG--QVWTQCHSLAFDYSVWEI 2165 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPE---GL 291 WGALL+GGRL+VVP++V SP++LH LL++E+VSVL QTPSA A L PE L Sbjct: 2166 WGALLYGGRLLVVPDAVVRSPEELHALLVSEEVSVLSQTPSAFYALQTADALQPEMGQQL 2225 Query: 292 ESTTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSEPLXXXXXXXXXXX 347 + T++ GEA + + W PG MIN YG TE T++A+ E Sbjct: 2226 KLQTVVFGGEALEPQRLSSWFDSHPGLPRMINMYGITETTVHASFREIDDGDVDSNSSPI 2285 Query: 348 XXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 L FVLD WLR P GVVGELYVAG G A+GY+GR DLT +RFVACPFG G R Sbjct: 2286 GVPLEHLAFFVLDGWLRKVPVGVVGELYVAGSGQASGYLGRSDLTTTRFVACPFGAPGSR 2345 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLV+WG DGQL Y+GRAD+QVKIRGYRIELGE+ AALA++ GVDQA VIAREDRP Sbjct: 2346 MYRTGDLVQWGEDGQLRYVGRADKQVKIRGYRIELGEVHAALARVAGVDQAAVIAREDRP 2405 Query: 466 GDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPA 521 GDKRLVGYIT GT DP +R LAE LP+YMVP AVVVLD +PLTVNGKLD RALPA Sbjct: 2406 GDKRLVGYITESTAGTLDPTAVRATLAERLPSYMVPAAVVVLDALPLTVNGKLDTRALPA 2465 Query: 522 PEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA 581 PE++ A + YRAP E+ILA +YAQVLGVE++GVDDSFFDLGGDSI SMQVVARARAA Sbjct: 2466 PEFQDA-DHYRAPEDAVEEILAGIYAQVLGVEQIGVDDSFFDLGGDSISSMQVVARARAA 2524 Query: 582 GIQCRPRDIFVEQTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQ 640 G+ RPRDIFVEQT E+ VVD G GPVVATPI+RWL + G G+FNQ Sbjct: 2525 GLLLRPRDIFVEQTVSRLAQVAVFADGEATVVDAGTGPVVATPIIRWLHGLGGNVGEFNQ 2584 Query: 641 TVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR 700 TV+ QAP GV+EDDVV +LQALLDRHATLRLR E E+ EW+LL+PE G V AR CL Sbjct: 2585 TVVLQAPEGVSEDDVVTVLQALLDRHATLRLRAE---ENDGEWALLIPEVGTVDARACLL 2641 Query: 701 TVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIA 760 V+AL+D+ L AR+RL+PA G+M+SA+W ++LVL++HHLAVD VSWRILLED NIA Sbjct: 2642 AVEALSDEALRHARSRLNPATGSMLSALWESGKNRLVLIVHHLAVDAVSWRILLEDFNIA 2701 Query: 761 WAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTD 820 WAQH GQ++ELP+GGTSFARW+ LL E A+T V L D WR V +P ALP V P D Sbjct: 2702 WAQHHGGQAVELPSGGTSFARWATLLDERARTADVEALTDTWRQVEKIPPALPAVHPTMD 2761 Query: 821 TYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVE 880 TY +AGQLS SLD + TR+LLGEVP A+ AGVQDILL+AF LAW EFL + PIG+DVE Sbjct: 2762 TYASAGQLSVSLDADLTRELLGEVPVAYHAGVQDILLIAFALAWNEFLGSAGAPIGIDVE 2821 Query: 881 GHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSL 940 GHGR +E +D DLSRTVGWFT+KYPV+L V L W QVVAGD ALG ++K KEQLR+L Sbjct: 2822 GHGRNEEFVADADLSRTVGWFTSKYPVSLAVGELSWAQVVAGDPALGPVIKGAKEQLRTL 2881 Query: 941 PEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXX 1000 P+GLTYGLLRYLNP+ D+ G DP+IGFNYLGRLGAG +LS++LWRIDQ Sbjct: 2882 PDGLTYGLLRYLNPDADVAGPDPSIGFNYLGRLGAGGVDLSDDLWRIDQDGVAITAAATA 2941 Query: 1001 VPMPLMHTVELNAGTI-DTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVR 1059 VP PL HTVELNAG + D D G L A+WTWA SA Q R+SRLWF++LAGICAHVR Sbjct: 2942 VPTPLGHTVELNAGVMEDADAGARLHATWTWALSALSHNQVDRISRLWFDSLAGICAHVR 3001 Query: 1060 GGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFA-RGI--GDDV 1116 GGGGGL+PSDV PARLTQ+QID+L ++Y++ DVLPLTP+QQGLLFHS A G+ DD+ Sbjct: 3002 GGGGGLSPSDVMPARLTQQQIDQLDEQYEIADVLPLTPLQQGLLFHSNLAPEGLEGSDDL 3061 Query: 1117 YAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDL 1176 YAVQLD+ ++G LD RL+DAVH+ + R PN+ ARF E+FGEPVQ++ ADP +AW+YL+L Sbjct: 3062 YAVQLDVALSGPLDPKRLQDAVHSAIRRRPNVVARFYEEFGEPVQLIPADPELAWQYLEL 3121 Query: 1177 RGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLP 1236 D + ++E+L A+ER+AVCDL +P FRAAL RT +Q+RF++T HHIV+DGWS P Sbjct: 3122 DADS-EAEEQVERLAASERAAVCDLAGQPAFRAALARTGTDQYRFLVTNHHIVLDGWSKP 3180 Query: 1237 ILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG--V 1294 ILLQEIFA YFG RLPA YR FV WL W +V +GFETPTLV PPG V Sbjct: 3181 ILLQEIFASYFGERLPAPVAYRRFVTWLSGQDNDAARSAWGKVFEGFETPTLVGPPGRMV 3240 Query: 1295 PGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR 1354 G RG+ES+ VSAETT+ALGELARS TT++TVLQAAW QLLM +TGQ DVAFGTAVSGR Sbjct: 3241 LGRRGVESFEVSAETTQALGELARSCRTTVSTVLQAAWAQLLMWLTGQTDVAFGTAVSGR 3300 Query: 1355 PADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG 1414 P DL GAESMVGLLINTVP+RA ++ DTT+ LL QLQ+ + +TLEH+HLAL +IHH G Sbjct: 3301 PTDLVGAESMVGLLINTVPVRATITPDTTIASLLNQLQAAYGETLEHQHLALKEIHHAVG 3360 Query: 1415 HEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDT 1474 H+QLFDT+F+YE+YPIDT+A V EL++T F+NREYNHYPL+V A PGHELGLRVE+DT Sbjct: 3361 HDQLFDTMFVYENYPIDTAALSRVHELSITGFSNREYNHYPLAVQATPGHELGLRVEFDT 3420 Query: 1475 SVFDVSEIETLIDRFQRLLEAMIDD 1499 VF+ I L+ RFQR+LEAM D Sbjct: 3421 DVFNAVRIGKLVKRFQRVLEAMTSD 3445 Score = 719 bits (1856), Expect = 0.0 Identities = 455/1007 (45%), Positives = 566/1007 (56%), Gaps = 37/1007 (3%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 + I G +++ L A+ V A F E G+ VQ + + DLR D Sbjct: 37 VRIEGQVERVLLERAIRQAVTEAEPARAAFFEVDGQIVQRPIDHSDLELAFEDLRDSDDP 96 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 ++ +R+ + L + AL RT+ ++ HHI +DG + ++ + + Sbjct: 97 AGLARKKATDIQRTLMP--LTGQLLKFALYRTADDEFHLFGLCHHINLDGLGMAVVSRRV 154 Query: 1243 FAGYF----GHRLPAA--APYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVP- 1295 + Y G +P A ++ V+W RE P +P Sbjct: 155 ASIYTALATGEPIPPAYFGTLQDLVDWETDYVASAEYAEDREYWSNNLPPDSGLDYRMPH 214 Query: 1296 ------GPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMR--MTGQRDVAF 1347 G + +S ++ T + EL + +V+ AA LL+R T +VA Sbjct: 215 ASEESDGYKPSDSVQMDDVTVSEIKELTKVLRIRRYSVITAACA-LLVRGWSTSGSEVAL 273 Query: 1348 GTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALN 1407 VS R + ++ G++ VP+ +TV + R + + + L+H+ Sbjct: 274 DFPVSRRVHP--DSRTLPGMMAGVVPLVLNAPPQSTVAEFCRHVDTRIRELLQHQRFP-- 329 Query: 1408 DIHHVSGHE-QLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMAL----P 1462 +H + E L ++ +LA NH P+ L Sbjct: 330 -VHTLEDEEFGLRGPRHAGNRVAVNFIPARLTLDLAGAPATASYTNHGPMGHFGLFFIGA 388 Query: 1463 GHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWA 1522 +L L D F + L R QRLL M DP RRLSS+D + +DE L E Sbjct: 389 SDQLVLSSSGDGEPFARFGVPNLAVRLQRLLSEMAADPDRRLSSLDSLVNDELADLAELG 448 Query: 1523 NRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGA 1582 NRA+LT P P SIPE+F QV +P+A A+TF G SL Y ELDEAA++LA L G Sbjct: 449 NRAILTAPAARPVSIPELFTAQVSAEPDAVALTFGGSSLTYRELDEAADRLAIQLGHRGV 508 Query: 1583 APGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDL 1642 PG V L RSA A++ ILAVLKTGAAYLP+DP+VPA+RLEF++ DA PVAA+TT DL Sbjct: 509 GPGDRVILFSDRSARAVIGILAVLKTGAAYLPVDPAVPASRLEFIVSDAAPVAAITTTDL 568 Query: 1643 RSRFDGFDLQVVEVD---DPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGN 1699 R R DGF L V+++D D E P+PDDIAY+IYTSGTTG PKGVA+TH N Sbjct: 569 RGRLDGFGLAVIDLDAHTDSPAEGQSGLVPAAPAPDDIAYIIYTSGTTGAPKGVAVTHHN 628 Query: 1700 VTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLH 1759 VTQ++ +L A LP PG VW HSL FDVSVWEIWGALL GGRL +VPESI SP D H Sbjct: 629 VTQLMQSLDAGLPK-PG-VWPLCHSLAFDVSVWEIWGALLRGGRLAVVPESITASPADFH 686 Query: 1760 ALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTE 1819 LLV+E V VL QTPSAV M+SP+GLE TAL V GEACP VVD+WA R MINAYGPTE Sbjct: 687 DLLVAEQVTVLTQTPSAVAMLSPDGLESTALAVVGEACPAAVVDKWAPGRTMINAYGPTE 746 Query: 1820 STIYAAISAPLSPG--SDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXX 1877 +T+ AISAPL VVPIGSPVP A FVLD WL+PVP GVVGELY+A Sbjct: 747 TTMCVAISAPLKADLPDAVVPIGSPVPGAALFVLDTWLQPVPAGVVGELYVAGDGVACGY 806 Query: 1878 XXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEI 1937 LT +RFVACPFG+PG RMYRTGDLV WGDDGQLQYLGRADEQVKIRGYRIELGE+ Sbjct: 807 VGRSDLTASRFVACPFGKPGTRMYRTGDLVLWGDDGQLQYLGRADEQVKIRGYRIELGEV 866 Query: 1938 QAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTL 1997 QAAL +DGVDQA I REDRPGDKRLVGY+TGTADPA R L+ RLP YMVPAAVV L Sbjct: 867 QAALGALDGVDQAAAIVREDRPGDKRLVGYVTGTADPAEIRGILSKRLPPYMVPAAVVVL 926 Query: 1998 ETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXX 2056 ETLPLT N KLD RALPAPEY YRAP E+ LAG++A VLGVER Sbjct: 927 ETLPLTSNNKLDTRALPAPEYGGLGADYRAPGNAVEEILAGVYAQVLGVERVGVDDSFFD 986 Query: 2057 XXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 +M+V A A R +F TV++L+ E GE Sbjct: 987 LGGDSILSMQVVARARAA-GVLCRPRDVFIEQTVSRLAAVAEVSGGE 1032 >tr|D5P2M6|D5P2M6_9MYCO Tax_Id=525368 SubName: Full=Syringomycin synthetase;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 8230 Score = 2542 bits (6588), Expect = 0.0 Identities = 1316/2098 (62%), Positives = 1556/2098 (74%), Gaps = 21/2098 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+PS R + S D+LDE EH ++ V GNRAVL P V+IP LFA QV RAPDAVA+ Sbjct: 3576 ITADPSRR-VSSIDVLDEAEHARLAVVGNRAVLHGPSRAGVSIPELFAAQVDRAPDAVAI 3634 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RSWTY ELDEASNRLAH+L E+GA PG VA L RS +A+ ++L+VLKTGAAYLP Sbjct: 3635 TCAQRSWTYGELDEASNRLAHLLIEYGAGPGECVALLAERSAQAVAAMLAVLKTGAAYLP 3694 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP P ARI FM++DA P+AA+TTA +RSRLD DLAV+D DP + +P P Sbjct: 3695 IDPGLPTARIEFMLADAIPIAAVTTAGVRSRLDGSDLAVLDFDDPELATQPGGPPPPPDA 3754 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +++AY+ YTSGTTGVPK VAVTHHNVTQL+ ++ +L G +VWSQ HSL FD SVWEI Sbjct: 3755 ENVAYVIYTSGTTGVPKGVAVTHHNVTQLLESVDRELELG--RVWSQCHSLAFDFSVWEI 3812 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLEST-TLIVA 299 +GALL G RLV+VP+ V SP+DLH +L+ E+V+VL TPSA L+P+GL+S TL++ Sbjct: 3813 FGALLRGARLVIVPDDVVRSPEDLHAMLVRERVTVLSYTPSAVAGLAPQGLDSVATLVMG 3872 Query: 300 GEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 GE CP E+VDRWAPGRVM+N YGPTE T+YAAM+ PL LFVLD+ Sbjct: 3873 GEPCPPEVVDRWAPGRVMVNQYGPTETTMYAAMTAPLTAGAGTPPIGSPVPGAALFVLDR 3932 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFG---ETGERMYRTGDLVRWG 416 WLRP PEGVVGELYVAG GVA GY GRP LTASRFVACPFG G+RMYRTGDL RW Sbjct: 3933 WLRPVPEGVVGELYVAGRGVARGYPGRPGLTASRFVACPFGGPDAPGQRMYRTGDLARWD 3992 Query: 417 SDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITG 476 SDGQL YLGR D+QVKIRGYRIELGEI+AAL L GV QAVVI REDRPG KRLV Y+TG Sbjct: 3993 SDGQLHYLGRMDDQVKIRGYRIELGEIRAALTGLRGVGQAVVIVREDRPGYKRLVAYVTG 4052 Query: 477 TADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPST 536 TADPA LR LA+ LP YMVP A+V LD IPLT+NGKLD RALPAP++ SA + YRAP Sbjct: 4053 TADPAHLRGRLADRLPNYMVPAAIVALDDIPLTLNGKLDIRALPAPDFESAEH-YRAPGD 4111 Query: 537 PAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTX 596 E+ILA +YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ RPRD+FVEQT Sbjct: 4112 AVEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVVFRPRDVFVEQTV 4171 Query: 597 XXXXXXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVV 656 + VDEGVGPV ATPIMRWL VDGP +FNQT+I +AP GVT DDVV Sbjct: 4172 ARLARVAGVAIDDRAVDEGVGPVAATPIMRWLHSVDGPVEEFNQTMIVRAPDGVTHDDVV 4231 Query: 657 VILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNR 716 +LQAL+DRH LRL V+D + W+L E GA+ A C+ V+ALT + LV R+R Sbjct: 4232 ALLQALIDRHPMLRLCVDD--DGAGGWTLHAAEPGAIQAGGCVHAVEALTREALVAERSR 4289 Query: 717 LDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGG 776 L+PAAG M+ AVW T +L L++HHLAVDGVSWRILLEDLNIAWAQ +G+ + LPAGG Sbjct: 4290 LNPAAGVMLRAVWAEPTGRLALIVHHLAVDGVSWRILLEDLNIAWAQQQSGRPVTLPAGG 4349 Query: 777 TSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVET 836 TSFARWSALLAE A+ V A+AWR V + P LP + TDTY TA LS SLD E Sbjct: 4350 TSFARWSALLAERARRPEVVAQAEAWRRVAATPPPLPAPRSTTDTYETAEHLSVSLDPEI 4409 Query: 837 TRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSR 896 TR LLG VPAA+ AGVQDIL+VAFGLA EFL + P+ +DVEGHGR +++ VDLSR Sbjct: 4410 TRMLLGVVPAAYHAGVQDILVVAFGLAINEFLG-TGAPLCIDVEGHGRDEDVGPRVDLSR 4468 Query: 897 TVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEV 956 TVGWFT KYPVAL W ++V+G+A LG +VK KEQLR+LP+GLTYGLLRYLNPE Sbjct: 4469 TVGWFTAKYPVALRFGKPQWAKIVSGEAELGTLVKDAKEQLRALPDGLTYGLLRYLNPEA 4528 Query: 957 DLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTI 1016 L DP IGFNYLGRLG G ELS+ LWR+D+ +P+PL H +ELNAGT+ Sbjct: 4529 GLDDPDPVIGFNYLGRLG-GTAELSDALWRLDEDSLPLTAATAALPIPLGHALELNAGTM 4587 Query: 1017 DTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLT 1076 +T NGP L+A+WTWAPSA Q RLSRLW +ALAGICA VR GGGGLTPSD+APARL+ Sbjct: 4588 ETANGPVLQANWTWAPSALQRGQVRRLSRLWCDALAGICARVRNGGGGLTPSDIAPARLS 4647 Query: 1077 QRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRD 1136 Q+QIDEL +R+ DVLPLTP+QQGLLFH+ R GDDVYAVQLDIT+ G LD RLR+ Sbjct: 4648 QQQIDELCRRHPTADVLPLTPLQQGLLFHANTGRDPGDDVYAVQLDITVCGPLDPQRLRE 4707 Query: 1137 AVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERS 1196 AVHTV+ RHPNL ARF + F EPVQ++ +P +AWRYL L DD PD I QL AAER+ Sbjct: 4708 AVHTVLHRHPNLIARFCDDFDEPVQIIPPEPAMAWRYLQLDADDTDPDGRIGQLSAAERA 4767 Query: 1197 AVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP 1256 AVCDL P FRAALIRT +HRFVLT HHIV+DGWSLPI+LQEIFAGYF R+PAAAP Sbjct: 4768 AVCDLAAGPAFRAALIRTGEARHRFVLTVHHIVMDGWSLPIVLQEIFAGYFRERMPAAAP 4827 Query: 1257 YRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGEL 1316 YR ++ WL W++VLDGF+TPTLV PPG G RG+ ++ V A TTRALG L Sbjct: 4828 YRRYLTWLADRDVPAARAAWQQVLDGFDTPTLVRPPGRVGRRGVATFSVPAVTTRALGGL 4887 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA 1376 ARS TT++TVLQA W Q+L +TGQ DV FG VSGRPAD+ GAESMVGLLINTVP+RA Sbjct: 4888 ARSSLTTVSTVLQAGWAQVLAWLTGQDDVVFGAVVSGRPADVRGAESMVGLLINTVPVRA 4947 Query: 1377 KVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFM 1436 ++A TTV LL QL+ N TLEH+HLAL +IH +GHEQLFDTLF+YE+YPID +A Sbjct: 4948 TLTAATTVAGLLEQLRRAQNHTLEHQHLALPEIHRATGHEQLFDTLFVYENYPIDRAALA 5007 Query: 1437 GVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAM 1496 G E+ VT+F +RE+NHYPLSV A+PG ELGLRVE+DT VFD I +I+RF+R+LEAM Sbjct: 5008 GAHEVTVTDFTSREFNHYPLSVQAVPGDELGLRVEFDTEVFDADGIAAMIERFRRVLEAM 5067 Query: 1497 IDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTF 1556 DPAR LS++D +D+ E L W NRAVLT+PV + SIPE FA QV R P+A A+ F Sbjct: 5068 AADPARPLSTIDALDESEHVHLGAWGNRAVLTEPV-TGASIPEAFAVQVARSPDAVALRF 5126 Query: 1557 EGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPID 1616 EG SL Y ELDEAAN+LA+LLA GA PG VAL+ RSADAIVA+LAVLK+GAAYLPID Sbjct: 5127 EGRSLTYRELDEAANRLAHLLAERGAGPGTFVALLFSRSADAIVAMLAVLKSGAAYLPID 5186 Query: 1617 PSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDD 1676 P +P AR+ FM+ DA P+ A+TT +LR R DG L V++V DP+V P+T P+P+D Sbjct: 5187 PGLPDARIRFMIADASPIVALTTAELRPRLDGSALTVIDVHDPSVTARPATAPPAPAPED 5246 Query: 1677 IAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWG 1736 IAY+IYTSGTTG PKGVA+TH NVTQ++ +L A LPA VWSQ HS FDVSV EI+G Sbjct: 5247 IAYLIYTSGTTGAPKGVAVTHHNVTQLMASLHAPLPA--AGVWSQCHSPAFDVSVQEIFG 5304 Query: 1737 ALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEA 1796 ALL GGRLV+VPE + SP+DL ALL+ E V+VL QTPS +SPEGL+ ALV+ GE Sbjct: 5305 ALLDGGRLVVVPEPVVHSPEDLRALLIRERVSVLSQTPSEAGALSPEGLDAVALVIGGEP 5364 Query: 1797 CPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLR 1856 CP E+VDRWA RVM+NAYGPTE+T+ AAISAPL+ G+ PIGSPV A VLD+WLR Sbjct: 5365 CPDELVDRWAPGRVMVNAYGPTETTVDAAISAPLTAGAG-APIGSPVSGAALLVLDKWLR 5423 Query: 1857 PVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQ 1916 PVP GVVGELY+A LT +RF+ACPFG PGARMYRTGDLVRWG DGQL+ Sbjct: 5424 PVPAGVVGELYVAGRGVACGYLGRSGLTASRFIACPFGGPGARMYRTGDLVRWGTDGQLR 5483 Query: 1917 YLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAA 1976 Y+GRAD+QVKIRG+R+ELGEI AL+ + GV++A VIAR D RLVGYITGTADPA Sbjct: 5484 YVGRADDQVKIRGHRVELGEIHTALTALAGVERAAVIAR-----DGRLVGYITGTADPAG 5538 Query: 1977 ARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLA 2036 AR+ L RLPAYMVPAA+V ++ +PLTVNGKLD RALPAPEY A YRAP E LA Sbjct: 5539 ARAALAERLPAYMVPAAIVEVDAIPLTVNGKLDARALPAPEYHDADAYRAPANPIEGILA 5598 Query: 2037 GIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 I+A +LG+ R AMR+ AAVN LDA LSVRT+ EAPTV +L+ Sbjct: 5599 EIYARILGLARVGVDESFFDLGGDSLAAMRLAAAVNAGLDAQLSVRTVLEAPTVRRLA 5656 Score = 1357 bits (3511), Expect = 0.0 Identities = 777/1510 (51%), Positives = 966/1510 (63%), Gaps = 63/1510 (4%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ Q L F VY + + + G LD L A+ VVARH +L Sbjct: 6740 VIPLSFAQSRLWFLDQLQGPSA--VYNMAAALRLRGSLDVGALGAALGDVVARHESLRTV 6797 Query: 1152 FVEQFGEPVQVLT--ADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 FV G P Q++ A+ +A+ +D P + + A DL RA Sbjct: 6798 FVAAEGTPQQIVVPPAEADVAYDVVDATA---WPPGRLAEAVEAVAHYAFDLGTEIPLRA 6854 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNFVN 1262 L RT+G++H V HHI DG SL L++++ Y P A Y ++ Sbjct: 6855 WLFRTAGDEHVLVSVLHHIAADGLSLTPLVRDLGVAYARRCAGEPPGWAPLAVQYADYTL 6914 Query: 1263 WLXXXXXXXXXXX---------WREVLDGFETPTLVAPPGVPGP-----RGIE-SYRVSA 1307 W W L G LV P P P RG S + A Sbjct: 6915 WQRDQFGDLDDPDSPIAGQLRFWEHNLAGMPE-RLVLPTDRPYPLVADHRGATVSVQWPA 6973 Query: 1308 ETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGL 1367 E + + E+AR+ + T V+QAA LL ++G +VA G ++GR + + +VG Sbjct: 6974 ELQQRVREVARAHNATSFMVVQAALAVLLSTLSGSSEVAVGFPIAGRRDPVL--DDVVGF 7031 Query: 1368 LINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHE----HLALNDIHHVS--GHEQLFDT 1421 +NT+ +R + D TV +L Q++ EH+ + + +H GH L Sbjct: 7032 FVNTLVLRTDLGGDPTVAQVLAQVRGRSLAAYEHQDVPFEVLVERLHPARSLGHHPLVQV 7091 Query: 1422 LFLYESYPIDTSAF--MGVQELAVTEFNNREYNHYPLSVMALPGHE---LGLRVEYDTSV 1476 + ++ + V L V R + L+ G E +G +VE+ T V Sbjct: 7092 MLAWQGNDATDLRLGDLDVTPLPVDTHTARMDLTFSLAEHWGAGGEPAGIGGQVEFRTDV 7151 Query: 1477 FDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQS 1536 FD IETL+ R R+L A+ D R LSS+D++DD ER +LDEW NRA ++PV P S Sbjct: 7152 FDAGTIETLVKRLHRVLVAITADADRPLSSIDLLDDGERARLDEWGNRAACSRPVTCP-S 7210 Query: 1537 IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSA 1596 I F QV+ P+APA+ ++ Y ELD AAN+LA+LL GA PG+ V L+ RSA Sbjct: 7211 IVAAFTAQVDLAPKAPALCCGDRTMTYRELDRAANRLAHLLIDQGAGPGECVGLLAERSA 7270 Query: 1597 DAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEV 1656 +A+VAILAVLKTGAAYLPIDP +P AR+EF+L DA P+AAVTT LRSR DG+DL VV+V Sbjct: 7271 EAVVAILAVLKTGAAYLPIDPGLPPARIEFLLTDAAPIAAVTTAGLRSRLDGYDLAVVDV 7330 Query: 1657 DDPAVEIYPS-TTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGP 1715 DDPA++ P P+ DD+AY+IYTSGTTG PKGVA+TH NVTQ+ L A LP Sbjct: 7331 DDPALDTRPDGAPAAAPTADDVAYLIYTSGTTGTPKGVAVTHRNVTQLFAPLDAPLPVA- 7389 Query: 1716 GAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPS 1775 WS HSLVFDVSVWEI+GALLHGGR+++VP++ A SP +LHALL +E V+VL QTPS Sbjct: 7390 -GAWSHSHSLVFDVSVWEIFGALLHGGRVLVVPDATARSPRELHALLSAERVSVLTQTPS 7448 Query: 1776 AVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSD 1835 M+ EGL+ ALVVAGEACP EVVDRWA R M+N YGPTE+T+ A+SAPL+P S Sbjct: 7449 EAGMLPVEGLDSAALVVAGEACPEEVVDRWAPGRTMLNVYGPTETTMCVAVSAPLAPESR 7508 Query: 1836 VVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGE 1895 PIG+PVP A FVLD WLRP GVVGELY+A LT +RFVACPFG Sbjct: 7509 TPPIGAPVPGAALFVLDGWLRPAATGVVGELYVAGAGVTYGYVRRSGLTASRFVACPFGA 7568 Query: 1896 PGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAR 1955 PGARMYRTGDL WG DGQLQYLGRAD+QVKIRG+RIELGEI+ AL+ + GV+QA V+AR Sbjct: 7569 PGARMYRTGDLACWGPDGQLQYLGRADDQVKIRGHRIELGEIRTALTGLGGVEQAAVVAR 7628 Query: 1956 EDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPA 2015 EDRPGDKRLVGY+TGTAD AA R L +RLPAYMVPAAVV L+ LPLTVNGKLD RALPA Sbjct: 7629 EDRPGDKRLVGYVTGTADAAALRVALADRLPAYMVPAAVVVLDALPLTVNGKLDTRALPA 7688 Query: 2016 PEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTAL 2075 P Y YR P T E+TLA I+A VLG+ER AMR+ AA+ + L Sbjct: 7689 PAYTDGDGYRPPATPVEETLADIYAQVLGMERVGVQESFFDLGGDSLSAMRLVAAIQSTL 7748 Query: 2076 DADLSVRTLFEAPTVAKLSLHVEHDAGE--RTDRVSFAAVHGSDVTEVHARDLTLDKFIX 2133 L VR +F+AP+V L+ ++ A E + R +FA+VHG D TEV+A DLTLDKF+ Sbjct: 7749 GVHLPVRAVFDAPSVRNLAQQLDRHAEEAAQPGRATFASVHGRDATEVYASDLTLDKFVD 7808 Query: 2134 XXXXXXXXXXXXXXGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDA 2193 V+TVLLTGATGFLGRYL L+WL QL VD +ICLVR SDE+A Sbjct: 7809 AATLGNAPALPGPGAQVRTVLLTGATGFLGRYLALQWLEQLELVDGTLICLVRAGSDEEA 7868 Query: 2194 RRRLEATFDT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSA 2252 RRRLE TFD+ DP L HF LA L+V+AGDKG NLGLDE+TWQRLA++VDLIVD A Sbjct: 7869 RRRLETTFDSGDPRLLAHFAGLAAHHLEVLAGDKGATNLGLDERTWQRLADTVDLIVDCA 7928 Query: 2253 AFVNSVLPYSELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRL 2312 A VN VLPY ELFGPNV GTAELIR ALT++LKP+ FVST++VG ++ + FTE ADIR Sbjct: 7929 AVVNGVLPYRELFGPNVAGTAELIRLALTTRLKPYTFVSTANVGDGVDRAAFTEDADIRA 7988 Query: 2313 VSATRKIEVGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDT 2372 +S TR I+ GY+NGYGNSKWAGEVLLREAHD CGLPV VFR MI+ D +YAGQLN++D Sbjct: 7989 ISPTRIIDGGYSNGYGNSKWAGEVLLREAHDLCGLPVTVFRCDMILADTSYAGQLNLSDM 8048 Query: 2373 VSRMVLSIVATGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTA 2432 +RMVLSI ATGVAP SFY+ G RQR+HFD LPV+FVA+A+T LG A++V Sbjct: 8049 FTRMVLSIAATGVAPRSFYRLDAEGNRQRSHFDALPVEFVAEAVTALG---AKAV----- 8100 Query: 2433 SGFETYHVMNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNS 2492 +GF TYHVMNPHDDGIGID Y+DWLIEAGYPIERI+DFGEWL+RFEAAL+ L ++QRQ+S Sbjct: 8101 AGFGTYHVMNPHDDGIGIDEYVDWLIEAGYPIERIDDFGEWLRRFEAALRELPERQRQHS 8160 Query: 2493 VLQMLTLLKQQAGELQPPVPTRGSFAPADRFQAAVRDANIGVEG---EIPHVTREVIVKY 2549 VL +L L +++P P RG+ A DRF+AAVR+A IG +G +IP V+ VIVKY Sbjct: 8161 VLPLLQL--PSTRQVEPGAPARGALASTDRFRAAVREAKIGPDGDDPDIPRVSPPVIVKY 8218 Query: 2550 VTDLQLLGLL 2559 VTDLQLLGLL Sbjct: 8219 VTDLQLLGLL 8228 Score = 819 bits (2115), Expect = 0.0 Identities = 499/1078 (46%), Positives = 631/1078 (58%), Gaps = 59/1078 (5%) Query: 1060 GGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAV 1119 G GGG VA AR V+PL+ Q L F VY + Sbjct: 2079 GAGGGRAARVVAGARPA---------------VVPLSFAQSRLWFTGQLQGP--SPVYNM 2121 Query: 1120 QLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPM--IAWRYLDLR 1177 + + G +D LR A+ VVARH +L F+ + G P QV+ WR +D Sbjct: 2122 AAAMRLDGRVDVEALRAALGDVVARHESLRTVFMARKGTPQQVVVPAERADFGWRVVDAL 2181 Query: 1178 GDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPI 1237 G P +++ A DL RA L R N+H V HHI DG SL Sbjct: 2182 G---WPASRLDEAIEAAAHHPFDLANEVPLRAKLFRVDANRHVLVAVAHHIAADGSSLKP 2238 Query: 1238 LLQEIFAGYF----GHRLPAA---APYRNFVNWLXXXXXXXXXXX---------WREVLD 1281 L+ ++ Y GH P A Y ++ W W+ L Sbjct: 2239 LVADLGLAYASRCAGHAPPWAPLPVQYIDYTLWQQARLGDLDDPGSPIAGQLRYWQHALA 2298 Query: 1282 GFET----PTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHTTINTVLQAAWTQLL 1336 G PT P V RG S AE + + E AR+ + T V+QA LL Sbjct: 2299 GLPERLALPTDRPYPAVADHRGASVSVDWPAEVQQRVREAARAHNATSFMVIQAGLAVLL 2358 Query: 1337 MRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHN 1396 +++ DVA G ++GRP + +VG +NT+ +R ++ + T+ ++L Q++ Sbjct: 2359 AKVSATSDVAVGFPIAGRPDP--ALDELVGFFVNTLVLRVDLAGNPTLAEVLAQVRQRSL 2416 Query: 1397 DTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYPIDTS-AFMGVQELAVTEFNN 1448 EH+ + LN ++ H + L + P + S + V L V+ Sbjct: 2417 AAYEHQDVPFEALVERLNPSRSLAHHPLVQVMLTWQNNGPAELSLGELQVTPLPVSTRTA 2476 Query: 1449 REYNHYPLSVMALPGHE---LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLS 1505 R + L+ G + +G VE+ T VFD I TLIDR +R+L+AM DP R LS Sbjct: 2477 RMDLVFSLAERWTDGGQPAGIGGAVEFRTDVFDADTITTLIDRLRRVLDAMTTDPGRPLS 2536 Query: 1506 SMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGE 1565 + D +D E L+E NRAVL + P SIP +FA Q R P+A AV+ G SL YGE Sbjct: 2537 ATDALDAAEHRLLEEMGNRAVLARSW-VPVSIPGLFAAQATRTPDAVAVSCAGASLTYGE 2595 Query: 1566 LDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLE 1625 L+E+AN+LA++L GA G SVA+++ RS +AIVAILAVLKTGAAYLPIDP++PAAR+E Sbjct: 2596 LEESANRLAHVLIERGAGRGASVAVVLSRSTEAIVAILAVLKTGAAYLPIDPALPAARIE 2655 Query: 1626 FMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLT-PSPDDIAYMIYTS 1684 FML D PVAAV+T L + G+ L +V+V PA+ P+T P P+D+A++IYTS Sbjct: 2656 FMLSDTAPVAAVSTAALAEKLAGYVLPMVDVHSPALAGQPATAPAPGPEPEDVAHIIYTS 2715 Query: 1685 GTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRL 1744 GTTGVPKGVA++H NVT++ D + G G VWSQ+HS FD SVWEIWGALLHGGRL Sbjct: 2716 GTTGVPKGVAVSHANVTRLFDAPEVGVVLGSGQVWSQFHSYAFDFSVWEIWGALLHGGRL 2775 Query: 1745 VIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDR 1804 V+VPE++A SP D HALLV+EGV VL QTP+AVRM+SP+GLEGTALV+ E P EVVDR Sbjct: 2776 VVVPEAVARSPKDFHALLVAEGVTVLSQTPAAVRMLSPQGLEGTALVIGAEPVPAEVVDR 2835 Query: 1805 WAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVG 1864 WA RVM+N YGPTE+TI+A SA L PIGS VP A FVLD WLRP P GVVG Sbjct: 2836 WAPGRVMVNVYGPTETTIFATASAALVAKGGAPPIGSAVPGAALFVLDGWLRPTPVGVVG 2895 Query: 1865 ELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQ 1924 ELY+A LTG+RFVACPFG PGARMYRTGDLV WG DGQL+Y+GRAD Q Sbjct: 2896 ELYVAGRGVGLGYVRRAGLTGSRFVACPFGAPGARMYRTGDLVCWGADGQLRYVGRADAQ 2955 Query: 1925 VKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNR 1984 VKIRGYRIE+GEIQ+AL+ +DGV+QAVV+ REDRPGDKRLVGY+TGTA+PAA R+ L R Sbjct: 2956 VKIRGYRIEIGEIQSALAALDGVEQAVVVVREDRPGDKRLVGYLTGTAEPAALRTALAER 3015 Query: 1985 LPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLG 2044 LP YMVPAA+V L LP+TVNGKLD RALPAPEY A YRAP T TE+ LAGI+A VLG Sbjct: 3016 LPGYMVPAALVALPELPMTVNGKLDTRALPAPEYH-ASGYRAPSTPTEEILAGIYAQVLG 3074 Query: 2045 VERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 V+R AMR AA+N+ LD LSVR LFEAPTVA+L+ + G Sbjct: 3075 VDRVGIDQSFFDLGGDSLSAMRAVAAINSGLDRALSVRALFEAPTVAQLAPRIGGSGG 3132 Score = 774 bits (1998), Expect = 0.0 Identities = 490/1097 (44%), Positives = 624/1097 (56%), Gaps = 80/1097 (7%) Query: 1045 RLWFEA--LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGL 1102 R FEA +A + + G GGGL A +R + V+PL+ Q L Sbjct: 3112 RALFEAPTVAQLAPRIGGSGGGL-----AALVAGERPV-----------VVPLSFAQSRL 3155 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 F VY + + + G LD LR A+ VVARH +L F G P QV Sbjct: 3156 WFIDQLNGP--SPVYNMAAALRLRGRLDTAALRAALADVVARHESLRTVFAAPDGTPQQV 3213 Query: 1163 LTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFV 1222 + + R+ D+ D +E+ A S DL RA L R +H V Sbjct: 3214 VLPPARASVRW-DVVKTDGWSSSRLEEAIEAAASYPFDLAAEIPLRATLFRVGAGEHVLV 3272 Query: 1223 LTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP--------YRNFVNWLXXXXXXXXXX 1274 HHI DGWSL L ++ Y R AP Y ++ W Sbjct: 3273 AVAHHIAADGWSLRPLAADLGVAY-ASRCAGEAPGWAELPVQYVDYTLWQRAQFGDLDDP 3331 Query: 1275 X---------WREVLDGF----ETPTLVAPPGVPGPRGIESYRVSAETTRALG----ELA 1317 W++ L G E PT P V RG RV+ E L ELA Sbjct: 3332 HSAIAAQLAYWQDALAGMPERLELPTDRPYPPVADYRGA---RVAVEWPPELQVLVRELA 3388 Query: 1318 RSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIR 1375 + T V+QAA LL ++ DVA G ++GR PA + +VG +NT+ +R Sbjct: 3389 GEHNATSFMVVQAALAVLLSKVGATSDVAVGFPIAGRRDPA----LDDLVGFFVNTLVLR 3444 Query: 1376 AKVSADTTVGDLLRQLQSHHNDTLEHE----HLALNDIHHVSG--HEQLFDTLFLYESYP 1429 + + TV +LL Q+Q EH+ + + +H H L + +++ Sbjct: 3445 TDLGGNPTVAELLAQVQQRSLAAYEHQDVPFEVLVERLHPTRSLTHHPLIQVVLAWQNVE 3504 Query: 1430 IDTSAFMGVQELAVTEFNNREYNHYPLSVMALP------GHELGL--RVEYDTSVFDVSE 1481 A + + +L VT + V +L G G+ VE+ T VFD + Sbjct: 3505 F---ADLNLGDLEVTPLPTETRSARMDLVFSLAERWTEDGRPAGIGGAVEFRTDVFDTAR 3561 Query: 1482 IETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVF 1541 IE LI+R +L A+ DP+RR+SS+DV+D+ E +L NRAVL P + SIPE+F Sbjct: 3562 IEALIERLHHVLVAITADPSRRVSSIDVLDEAEHARLAVVGNRAVLHGPSRAGVSIPELF 3621 Query: 1542 ARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVA 1601 A QV+R P+A A+T S YGELDEA+N+LA+LL YGA PG+ VAL+ RSA A+ A Sbjct: 3622 AAQVDRAPDAVAITCAQRSWTYGELDEASNRLAHLLIEYGAGPGECVALLAERSAQAVAA 3681 Query: 1602 ILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAV 1661 +LAVLKTGAAYLPIDP +P AR+EFML DA P+AAVTT +RSR DG DL V++ DDP + Sbjct: 3682 MLAVLKTGAAYLPIDPGLPTARIEFMLADAIPIAAVTTAGVRSRLDGSDLAVLDFDDPEL 3741 Query: 1662 EIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQ 1721 P P +++AY+IYTSGTTGVPKGVA+TH NVTQ+L+++ EL G VWSQ Sbjct: 3742 ATQPGGPPPPPDAENVAYVIYTSGTTGVPKGVAVTHHNVTQLLESVDRELEL--GRVWSQ 3799 Query: 1722 WHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS 1781 HSL FD SVWEI+GALL G RLVIVP+ + SP+DLHA+LV E V VL TPSAV ++ Sbjct: 3800 CHSLAFDFSVWEIFGALLRGARLVIVPDDVVRSPEDLHAMLVRERVTVLSYTPSAVAGLA 3859 Query: 1782 PEGLEGTA-LVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIG 1840 P+GL+ A LV+ GE CP EVVDRWA RVM+N YGPTE+T+YAA++APL+ G+ PIG Sbjct: 3860 PQGLDSVATLVMGGEPCPPEVVDRWAPGRVMVNQYGPTETTMYAAMTAPLTAGAGTPPIG 3919 Query: 1841 SPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFG---EPG 1897 SPVP A FVLD WLRPVP GVVGELY+A LT +RFVACPFG PG Sbjct: 3920 SPVPGAALFVLDRWLRPVPEGVVGELYVAGRGVARGYPGRPGLTASRFVACPFGGPDAPG 3979 Query: 1898 ARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARED 1957 RMYRTGDL RW DGQL YLGR D+QVKIRGYRIELGEI+AAL+ + GV QAVVI RED Sbjct: 3980 QRMYRTGDLARWDSDGQLHYLGRMDDQVKIRGYRIELGEIRAALTGLRGVGQAVVIVRED 4039 Query: 1958 RPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPE 2017 RPG KRLV Y+TGTADPA R L +RLP YMVPAA+V L+ +PLT+NGKLD RALPAP+ Sbjct: 4040 RPGYKRLVAYVTGTADPAHLRGRLADRLPNYMVPAAIVALDDIPLTLNGKLDIRALPAPD 4099 Query: 2018 YQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDA 2077 ++SA+ YRAP E+ LAGI+A VLGVER +M+V A A Sbjct: 4100 FESAEHYRAPGDAVEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GV 4158 Query: 2078 DLSVRTLFEAPTVAKLS 2094 R +F TVA+L+ Sbjct: 4159 VFRPRDVFVEQTVARLA 4175 Score = 761 bits (1966), Expect = 0.0 Identities = 466/1072 (43%), Positives = 618/1072 (57%), Gaps = 68/1072 (6%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 VLPL+ Q L F VY + + + G L L A+ V+ARH L Sbjct: 5677 VLPLSFAQSRLWFIDQLHGP--SPVYNMAAALRLRGHLAVDALAAALTDVLARHETLRTV 5734 Query: 1152 FVEQFGEPVQVLTADPMIA--WRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 FV G P QV+ A W +D G P + + A + DL RA Sbjct: 5735 FVAVEGTPRQVVVPPERAAAGWDVVDAAG---WPAERLREAVEAAAADPFDLSAEMPLRA 5791 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVN 1262 L R + ++H V HHI DGWSL L++++ Y G R P+ AP Y ++ Sbjct: 5792 RLFRVAEDEHLLVAVLHHIAADGWSLTPLVRDLGVAYAGRCAGRAPSWAPLAVQYADYTL 5851 Query: 1263 WLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAE 1308 W WR+ LDG E PT P V RG + AE Sbjct: 5852 WQREQLGDLDDPDSPIAGQLRYWRDALDGMPERLELPTDRPYPAVADHRGATLAVEWPAE 5911 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVG 1366 + ELAR+ + T V+QA LL +++ DVA G ++GR PA + +VG Sbjct: 5912 LQDGVRELARAHNATSFMVVQAVLAVLLAKLSASSDVAVGFPIAGRRDPA----LDDVVG 5967 Query: 1367 LLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQLF 1419 +NT+ +R + + TV D+L Q++ EH+ + LN + GH L Sbjct: 5968 FFVNTLVLRVDLGGNPTVADVLAQVRRRSLAAYEHQDVPFEVLVERLNPTRSL-GHHPLV 6026 Query: 1420 DTLFLYESY-PIDTSAFMGVQELAVTEFNNREYNHYPLSVMAL----PGHELGL--RVEY 1472 + +++ P+D S +G ++ + R L +A G G+ VE+ Sbjct: 6027 QVMLAWQNNEPVDLS--LGDLQVTALPVDTRTARTDLLFSLAERWTGDGRSAGIGGAVEF 6084 Query: 1473 DTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVD 1532 T VFD + + TL+ R +R++ AM ++P RRLSS+DV+D+ E +L+ N A L++P Sbjct: 6085 RTDVFDTATVATLVARLRRVVAAMAEEPGRRLSSIDVLDEAEHARLEVVGNHAALSRPTP 6144 Query: 1533 SPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMV 1592 + SIP++F V R P+A A+ S YG+ D AAN+LA+LL +GA PG+ VAL++ Sbjct: 6145 AGLSIPQLFTASVNRSPDAVAINCGDRSWTYGQFDVAANRLAHLLIEHGAGPGERVALLI 6204 Query: 1593 PRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQ 1652 PRSA A+ A+LAVLK+GAAY+PIDP +PAAR+ FML D+ PVA +TT LRSR DG L Sbjct: 6205 PRSAGAVAAMLAVLKSGAAYVPIDPGLPAARIAFMLSDSAPVAVLTTSGLRSRLDGCGLP 6264 Query: 1653 VVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELP 1712 V+E+DDP V+ P T L P P+D+AY+IYTSGTTG+PKGVA+TH NV Q+LD+L EL Sbjct: 6265 VLEIDDPVVDTLPGTALPPPRPEDVAYIIYTSGTTGIPKGVAVTHRNVAQLLDSLDDELE 6324 Query: 1713 AGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQ 1772 G VW+Q HSL FD SVWEI+GALL GGRLV+V +++ SP++L+ALLV E V+VL Q Sbjct: 6325 LGQ--VWTQCHSLAFDFSVWEIFGALLRGGRLVVVSDAVVRSPEELYALLVREQVSVLSQ 6382 Query: 1773 TPSAVRMMSP---------EGLEGTALVVAGEACPTEVVDRWAVDRV----MINAYGPTE 1819 TPSA + + L+ LV GEA + RW + +IN YG TE Sbjct: 6383 TPSAFDALQTADALAPDLAQQLKLQTLVFGGEALEARRLGRWLDNHPGLPRLINMYGTTE 6442 Query: 1820 STIYAAIS--APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXX 1877 +T++A+ G D PIG P+ A FVLD WLRPVP GVVGEL++A Sbjct: 6443 TTVHASFRELGAGDVGGDASPIGGPLAHLAFFVLDRWLRPVPAGVVGELFVAGRGLACGY 6502 Query: 1878 XXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEI 1937 LTG+RFVACP G PG RMYRTGDLVRWG DGQL+YLGRAD+QVKIRG+RIELGEI Sbjct: 6503 VGRSGLTGSRFVACPSGPPGQRMYRTGDLVRWGADGQLRYLGRADDQVKIRGHRIELGEI 6562 Query: 1938 QAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTL 1997 L+ + GV +A VIAREDRPGDKRLVGY+TG+ADPAA R+ L RLPAYMVP+AVV + Sbjct: 6563 HTVLTGLAGVKRAAVIAREDRPGDKRLVGYVTGSADPAAIRAALAERLPAYMVPSAVVVV 6622 Query: 1998 ETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXX 2057 + +PLTVNGKLD RALPAP+Y+ A YRAP T TE+ LAGI+A VLG++R Sbjct: 6623 DAIPLTVNGKLDTRALPAPDYRGAAPYRAPATATEEILAGIYARVLGIDRVGVDDSFFDL 6682 Query: 2058 XXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVS 2109 AMR+ AAVN L+A L VR+LFEAPT+ L+ + D RT V+ Sbjct: 6683 GGDSLAAMRLIAAVNAGLNAHLGVRSLFEAPTIHLLAPRLGADGAGRTPLVA 6734 Score = 748 bits (1930), Expect = 0.0 Identities = 458/937 (48%), Positives = 570/937 (60%), Gaps = 70/937 (7%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P+ R L + D LDE EH + WGNRAVLT+P T +IP FA QV R+PDAVAL Sbjct: 5067 MAADPA-RPLSTIDALDESEHVHLGAWGNRAVLTEP-VTGASIPEAFAVQVARSPDAVAL 5124 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS TYRELDEA+NRLAH+LAE GA PG VA L RS +AI+++L+VLK+GAAYLP Sbjct: 5125 RFEGRSLTYRELDEAANRLAHLLAERGAGPGTFVALLFSRSADAIVAMLAVLKSGAAYLP 5184 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP PDARI FM++DA P+ ALTTA+LR RLD L VID+ DP++ RP+ A P P Sbjct: 5185 IDPGLPDARIRFMIADASPIVALTTAELRPRLDGSALTVIDVHDPSVTARPATAPPAPAP 5244 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +D+AY+ YTSGTTG PK VAVTHHNVTQL+++LHA LP+ VWSQ HS FDVSV EI Sbjct: 5245 EDIAYLIYTSGTTGAPKGVAVTHHNVTQLMASLHAPLPAAG--VWSQCHSPAFDVSVQEI 5302 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALL GGRLVVVPE V SP+DL LLI E+VSVL QTPS AG LSPEGL++ L++ G Sbjct: 5303 FGALLDGGRLVVVPEPVVHSPEDLRALLIRERVSVLSQTPSEAGALSPEGLDAVALVIGG 5362 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 E CP ELVDRWAPGRVM+NAYGPTE T+ AA+S PL L VLDKW Sbjct: 5363 EPCPDELVDRWAPGRVMVNAYGPTETTVDAAISAPLTAGAGAPIGSPVSGAA-LLVLDKW 5421 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELYVAG GVA GY+GR LTASRF+ACPFG G RMYRTGDLVRWG+DGQ Sbjct: 5422 LRPVPAGVVGELYVAGRGVACGYLGRSGLTASRFIACPFGGPGARMYRTGDLVRWGTDGQ 5481 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L Y+GRAD+QVKIRG+R+ELGEI AL L GV++A VIAR D RLVGYITGTADP Sbjct: 5482 LRYVGRADDQVKIRGHRVELGEIHTALTALAGVERAAVIAR-----DGRLVGYITGTADP 5536 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A R ALAE LPAYMVP A+V +D IPLTVNGKLD RALPAPEY A + YRAP+ P E Sbjct: 5537 AGARAALAERLPAYMVPAAIVEVDAIPLTVNGKLDARALPAPEYHDA-DAYRAPANPIEG 5595 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXX 599 ILA++YA++LG+ RVGVD+SFFDLGGDS+ +M++ A A Q R + T Sbjct: 5596 ILAEIYARILGLARVGVDESFFDLGGDSLAAMRLAAAVNAGLDAQLSVRTVLEAPTVRRL 5655 Query: 600 XXXXXXXXESHV-VDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTED 653 + V G P V A + ++ ++ GP+ +N + + D Sbjct: 5656 APLLGAGGDGPARVVAGPRPAVLPLSFAQSRLWFIDQLHGPSPVYNMAAALRLRGHLAVD 5715 Query: 654 DVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA-------LT 706 + L +L RH TLR V E T ++ PE A G VDA L Sbjct: 5716 ALAAALTDVLARHETLRT-VFVAVEGTPRQVVVPPERAAAG----WDVVDAAGWPAERLR 5770 Query: 707 DDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIAWAQ 763 + V A + D +A + A R LV ++HH+A DG S L+ DL +A+A Sbjct: 5771 EAVEAAAADPFDLSAEMPLRARLFRVAEDEHLLVAVLHHIAADGWSLTPLVRDLGVAYAG 5830 Query: 764 HCTGQSIELPAGGTSFARWSALLAEHA-----KTDTVRDLADA----------WR-AVTS 807 C G++ W+ L ++A + + + DL D WR A+ Sbjct: 5831 RCAGRA----------PSWAPLAVQYADYTLWQREQLGDLDDPDSPIAGQLRYWRDALDG 5880 Query: 808 VPQALPPVQPDTDTYVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVAFGLAW 864 +P+ L + D A A+L VE +L + E+ A A ++ + Sbjct: 5881 MPERL-ELPTDRPYPAVADHRGATLAVEWPAELQDGVRELARAHNATSFMVVQAVLAVLL 5939 Query: 865 TEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 + SD +G + GR D DV VG+F Sbjct: 5940 AKLSASSDVAVGFPIA--GRRDPALDDV-----VGFF 5969 Score = 746 bits (1925), Expect = 0.0 Identities = 463/1056 (43%), Positives = 609/1056 (57%), Gaps = 65/1056 (6%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 +V+PL+ Q L F G V+ + + + + G LD L A VVARH +L Sbjct: 1033 EVVPLSFAQSRLWFLDQL-HGCSP-VHNMAVALRLRGRLDADVLGTAFADVVARHESLRT 1090 Query: 1151 RFVEQFGEPVQVLT--ADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFR 1208 FV G P QV+ A W+ +D G P + + A DL R Sbjct: 1091 VFVAPEGTPRQVVVPAAHADFGWQVVDAGG---WPGARLAEAIDAVAHQPFDLTTEIPLR 1147 Query: 1209 AALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP--------YRNF 1260 A L R +H V HHI DGWS+ L++++ Y R A P Y ++ Sbjct: 1148 AKLFRVGAGEHVLVAVAHHIAADGWSITPLVRDLGIAY-ASRCAGAPPGWAELPVQYVDY 1206 Query: 1261 VNWLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVS 1306 W W + L G E PT P V RG + Sbjct: 1207 TLWQRAQFGDLEDPHSAITAQLAYWLDALAGMPERLEMPTDRPYPSVADYRGARVAVEWP 1266 Query: 1307 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESM 1364 E + + E+A + T V+Q A LL ++ DVA G ++GR PA + + Sbjct: 1267 PELQQRVSEVAGEHNATSFMVVQTALALLLAKLGATSDVAVGFPIAGRRDPA----LDEL 1322 Query: 1365 VGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHE----HLALNDIHHVSG--HEQL 1418 VG +NT+ +R + + TV ++L Q+Q EH+ + + +H H L Sbjct: 1323 VGFFVNTLVLRTDLGGNPTVAEVLAQVQQRSLAAYEHQDVPFEVLVERLHPTRSLTHHPL 1382 Query: 1419 FDTLFLYESYPID---TSAFMGVQELAVT-EFNNREYNHYPLSVMALP------GHELGL 1468 + +++ P +A + + ++ VT E + + L V +L G G+ Sbjct: 1383 IQVVLAWQNLPWQHDGPAAGLALGDVRVTPEPVDTQVARMDL-VFSLAERWTEDGRPAGI 1441 Query: 1469 --RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAV 1526 E+ T VFD + +E L+++F+R+L A+ DP +R+SS+DV+D+ E +L NRAV Sbjct: 1442 GGAAEFRTDVFDTASVEALVEQFRRVLVAVTADPTKRISSIDVLDEAEHARLAVVGNRAV 1501 Query: 1527 LTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGK 1586 L P + SIPE+FA QV+R P+A A+T S YGELDE +N+LA+LL YGA PG+ Sbjct: 1502 LHGPSRAGVSIPELFAAQVDRAPDAVAITCAQRSWTYGELDETSNRLAHLLIEYGAGPGE 1561 Query: 1587 SVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRF 1646 VAL+ RSA A+ A+LAVLKTGAAYLPIDP +PAAR+EF+LGDA P+AA+ T +RSR Sbjct: 1562 CVALLAERSAQAVAAMLAVLKTGAAYLPIDPGLPAARIEFLLGDAAPIAAIVTPGMRSRL 1621 Query: 1647 DGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDT 1706 DG DL ++VDDPAV + L P +++AY+IYTSGTTGVPKGVA+TH NVTQ+L++ Sbjct: 1622 DGSDLTALDVDDPAVATQSTDGLSPPDAENVAYVIYTSGTTGVPKGVAVTHHNVTQLLES 1681 Query: 1707 LPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEG 1766 + E G VWSQ HSL FD SVWEI+GALL G RLVIVP+ + SP+DLHA+LV E Sbjct: 1682 VDREFELG--RVWSQCHSLAFDFSVWEIFGALLRGARLVIVPDDVVRSPEDLHAMLVRER 1739 Query: 1767 VNVLYQTPSAVRMMSPEG--LEGTALVVAGEACPTEVVDRWAVDRV----MINAYGPTES 1820 V+VL QTPSA +SPE L+ +V GEA + RW +R +IN YG TE+ Sbjct: 1740 VSVLSQTPSAFYALSPEPSELKLQTVVFGGEALEPPRLGRWLHNRPKLPRLINMYGITET 1799 Query: 1821 TIYAAIS--APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXX 1878 T++A+ G PIG+P+ FVLDEWL PVP GV GELY+A Sbjct: 1800 TVHASFREITEADVGDTTSPIGAPLAHLGFFVLDEWLHPVPAGVTGELYVAGGGVACGYG 1859 Query: 1879 XXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQ 1938 LT +RFVACPFG G+RMYRTGDLVRWG DG+LQYLGRADEQVKIRGYRIELGEI+ Sbjct: 1860 GRAGLTASRFVACPFGAFGSRMYRTGDLVRWGADGRLQYLGRADEQVKIRGYRIELGEIR 1919 Query: 1939 AALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLE 1998 AAL+ D V+QA V+AREDRPGDKRLV Y+TGTADPA R+ L +RLP YMVPAAVV ++ Sbjct: 1920 AALTAFDEVEQAAVVAREDRPGDKRLVAYVTGTADPAHVRARLADRLPGYMVPAAVVAVD 1979 Query: 1999 TLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXX 2058 +PLT+NGKLD RALPAP+YQ YRAP T E+ LAGI+A VLG+ER Sbjct: 1980 AIPLTLNGKLDTRALPAPDYQEGGEYRAPATPVEEILAGIYARVLGLERVGVEESFFDLG 2039 Query: 2059 XXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 AMR+ AA T LDA L VRTLFEAPT+ +L+ Sbjct: 2040 GDSLSAMRLVAAAATGLDARLEVRTLFEAPTIRQLA 2075 Score = 724 bits (1869), Expect = 0.0 Identities = 415/801 (51%), Positives = 514/801 (64%), Gaps = 26/801 (3%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L + D LD EH +E GNRAVL PV+IP LFA Q R PDAVA+ Sbjct: 2527 MTTDPG-RPLSATDALDAAEHRLLEEMGNRAVLARSW-VPVSIPGLFAAQATRTPDAVAV 2584 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 S TY EL+E++NRLAHVL E GA GA+VA ++ RS EAI++IL+VLKTGAAYLP Sbjct: 2585 SCAGASLTYGELEESANRLAHVLIERGAGRGASVAVVLSRSTEAIVAILAVLKTGAAYLP 2644 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALS-GPR 179 +DPA P ARI FM+SD PVAA++TA L +L Y L ++D+ PA+ +P+ A + GP Sbjct: 2645 IDPALPAARIEFMLSDTAPVAAVSTAALAEKLAGYVLPMVDVHSPALAGQPATAPAPGPE 2704 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWE 239 P+D+A++ YTSGTTGVPK VAV+H NVT+L A + G GQVWSQ+HS FD SVWE Sbjct: 2705 PEDVAHIIYTSGTTGVPKGVAVSHANVTRLFDAPEVGVVLGSGQVWSQFHSYAFDFSVWE 2764 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVA 299 IWGALLHGGRLVVVPE+V SP D H LL+ E V+VL QTP+A MLSP+GLE T L++ Sbjct: 2765 IWGALLHGGRLVVVPEAVARSPKDFHALLVAEGVTVLSQTPAAVRMLSPQGLEGTALVIG 2824 Query: 300 GEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 E P E+VDRWAPGRVM+N YGPTE TI+A S L LFVLD Sbjct: 2825 AEPVPAEVVDRWAPGRVMVNVYGPTETTIFATASAALVAKGGAPPIGSAVPGAALFVLDG 2884 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WLRP P GVVGELYVAG GV GY+ R LT SRFVACPFG G RMYRTGDLV WG+DG Sbjct: 2885 WLRPTPVGVVGELYVAGRGVGLGYVRRAGLTGSRFVACPFGAPGARMYRTGDLVCWGADG 2944 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL Y+GRAD QVKIRGYRIE+GEIQ+ALA LDGV+QAVV+ REDRPGDKRLVGY+TGTA+ Sbjct: 2945 QLRYVGRADAQVKIRGYRIEIGEIQSALAALDGVEQAVVVVREDRPGDKRLVGYLTGTAE 3004 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA LRTALAE LP YMVP A+V L +P+TVNGKLD RALPAPEY A+ YRAPSTP E Sbjct: 3005 PAALRTALAERLPGYMVPAALVALPELPMTVNGKLDTRALPAPEYH--ASGYRAPSTPTE 3062 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQ--CRPRDIFVEQTXX 597 +ILA +YAQVLGV+RVG+D SFFDLGGDS+ +M+ VA A +G+ R +F T Sbjct: 3063 EILAGIYAQVLGVDRVGIDQSFFDLGGDSLSAMRAVA-AINSGLDRALSVRALFEAPTVA 3121 Query: 598 XXXXXXXXXXES-HVVDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVT 651 + G PVV A + ++ +++GP+ +N + + Sbjct: 3122 QLAPRIGGSGGGLAALVAGERPVVVPLSFAQSRLWFIDQLNGPSPVYNMAAALRLRGRLD 3181 Query: 652 EDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRT----VDALTD 707 + L ++ RH +LR D +++P A A + ++T L + Sbjct: 3182 TAALRAALADVVARHESLRTVF--AAPDGTPQQVVLPPARASVRWDVVKTDGWSSSRLEE 3239 Query: 708 DVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 + A D AA + A R + LV + HH+A DG S R L DL +A+A Sbjct: 3240 AIEAAASYPFDLAAEIPLRATLFRVGAGEHVLVAVAHHIAADGWSLRPLAADLGVAYASR 3299 Query: 765 CTGQS---IELPAGGTSFARW 782 C G++ ELP + W Sbjct: 3300 CAGEAPGWAELPVQYVDYTLW 3320 Score = 709 bits (1829), Expect = 0.0 Identities = 370/586 (63%), Positives = 435/586 (74%), Gaps = 6/586 (1%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R L S DLLD+ E +++ WGNRA + P P +I A F QV AP A AL GDR+ Sbjct: 7177 RPLSSIDLLDDGERARLDEWGNRAACSRPVTCP-SIVAAFTAQVDLAPKAPALCCGDRTM 7235 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 TYRELD A+NRLAH+L + GA PG V L RS EA+++IL+VLKTGAAYLP+DP P Sbjct: 7236 TYRELDRAANRLAHLLIDQGAGPGECVGLLAERSAEAVVAILAVLKTGAAYLPIDPGLPP 7295 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDA-LSGPRPDDLAYM 186 ARI F+++DA P+AA+TTA LRSRLD YDLAV+D+ DPA+D RP A + P DD+AY+ Sbjct: 7296 ARIEFLLTDAAPIAAVTTAGLRSRLDGYDLAVVDVDDPALDTRPDGAPAAAPTADDVAYL 7355 Query: 187 TYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLH 246 YTSGTTG PK VAVTH NVTQL + L A LP WS HSLVFDVSVWEI+GALLH Sbjct: 7356 IYTSGTTGTPKGVAVTHRNVTQLFAPLDAPLPVAGA--WSHSHSLVFDVSVWEIFGALLH 7413 Query: 247 GGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAGEACPTE 306 GGR++VVP++ SP +LH LL E+VSVL QTPS AGML EGL+S L+VAGEACP E Sbjct: 7414 GGRVLVVPDATARSPRELHALLSAERVSVLTQTPSEAGMLPVEGLDSAALVVAGEACPEE 7473 Query: 307 LVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPE 366 +VDRWAPGR M+N YGPTE T+ A+S PL LFVLD WLRPA Sbjct: 7474 VVDRWAPGRTMLNVYGPTETTMCVAVSAPLAPESRTPPIGAPVPGAALFVLDGWLRPAAT 7533 Query: 367 GVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGR 426 GVVGELYVAG GV GY+ R LTASRFVACPFG G RMYRTGDL WG DGQL+YLGR Sbjct: 7534 GVVGELYVAGAGVTYGYVRRSGLTASRFVACPFGAPGARMYRTGDLACWGPDGQLQYLGR 7593 Query: 427 ADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPAQLRTA 486 AD+QVKIRG+RIELGEI+ AL L GV+QA V+AREDRPGDKRLVGY+TGTAD A LR A Sbjct: 7594 ADDQVKIRGHRIELGEIRTALTGLGGVEQAAVVAREDRPGDKRLVGYVTGTADAAALRVA 7653 Query: 487 LAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVY 546 LA+ LPAYMVP AVVVLD +PLTVNGKLD RALPAP Y + + YR P+TP E+ LAD+Y Sbjct: 7654 LADRLPAYMVPAAVVVLDALPLTVNGKLDTRALPAPAY-TDGDGYRPPATPVEETLADIY 7712 Query: 547 AQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIF 591 AQVLG+ERVGV +SFFDLGGDS+ +M++VA ++ G+ R +F Sbjct: 7713 AQVLGMERVGVQESFFDLGGDSLSAMRLVAAIQSTLGVHLPVRAVF 7758 Score = 702 bits (1811), Expect = 0.0 Identities = 427/1009 (42%), Positives = 574/1009 (56%), Gaps = 29/1009 (2%) Query: 1117 YAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDL 1176 + + L +TI G + + L+ A+ + A F E G+ Q P + + DL Sbjct: 30 WQIGLFVTIDGGVQRDALKWAIRQALQEAEPARASFAEADGQVFQRAVDYPDVELAFHDL 89 Query: 1177 RGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLP 1236 G + + +R+ + P FR AL RT +Q HHI++DG + Sbjct: 90 SGSPDAVEEARRIALSIQRTPMP--FAGPLFRFALFRTRADQFHLFACCHHIILDGTGVA 147 Query: 1237 ILLQEIFAGYFG--HRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGV 1294 ++ I + Y P AP + L + + L A GV Sbjct: 148 LVGHRIASIYSAIVSAAPIPAPVFGSLRDLVDYESRYEASADYRRDEAYWIRHLPADDGV 207 Query: 1295 P--GPRGIES--------YRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQR- 1343 P PR + + R + +L+R + +V+ AA L+ +G Sbjct: 208 PHRAPRAAGDRDPWPSAPVALDSGVLRRVDKLSRVWGVSQTSVITAACALLVRGWSGDGP 267 Query: 1344 DVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEH 1403 +V V+ R A+++ G+L VP+ ++S + TV + RQ+ + + LEH+ Sbjct: 268 EVVLDFPVNRRVRP--EAKTLPGMLAGVVPLVLRLSPELTVAEFCRQVDTRVREALEHQR 325 Query: 1404 LALNDIHH----VSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVM 1459 + + +G + F+ ++ T F GV A + N+ + L + Sbjct: 326 FPVQALERKARGAAGPAERVSVNFVPAAF---TLPFGGVTASA-SYTNSGQVTGLGL-IF 380 Query: 1460 ALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLD 1519 + G L L F + L R +RLL A+ D RRL S+DV+D+ +R +L Sbjct: 381 SSDGDRLFLSTAGVWEPFSGFDAADLAGRLERLLVALTADTTRRLLSIDVLDEADRVRLA 440 Query: 1520 EWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAV 1579 W N AV+ + + ++IPE F Q R P A A++ EG +Y E+DEA+N+LA L Sbjct: 441 GWGNWAVMGRAAPAGRTIPEWFGVQAGRSPSAVAISCEGRRWSYREVDEASNRLARWLIG 500 Query: 1580 YGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTT 1639 G V L++ RSA+A++A+L VLK GAAY+P+DP +PA R+EFML DA P A + + Sbjct: 501 RGVGRRARVGLLMERSAEAVIAVLGVLKAGAAYVPMDPGLPAGRVEFMLADAAPAAVIVS 560 Query: 1640 GDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGN 1699 LR R F V +VDDP + P+ + PS DD+A++IYTSGTTGVPKGVA+TH N Sbjct: 561 AGLRPRLGEFAGVVADVDDPVIRQQPAAGVAGPSADDVAHVIYTSGTTGVPKGVAVTHRN 620 Query: 1700 VTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLH 1759 VTQ+ + L + G VWSQ HSL FD SVWEIWGALLHGG LV+VP+++ D+L Sbjct: 621 VTQLFEALAGDGLLSAGQVWSQCHSLAFDFSVWEIWGALLHGGHLVVVPDALTRRADELR 680 Query: 1760 ALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTE 1819 ALLV + V+VL QTPS++ +SP+G+ G ALVV EACP +VVDRWA R M+N YGPTE Sbjct: 681 ALLVGQRVSVLTQTPSSLGALSPDGV-GAALVVGAEACPAQVVDRWAPGRAMVNVYGPTE 739 Query: 1820 STIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXX 1879 +T++ A SAPL+ GS IGSPV A FVLD WLRPVPPGVVGELY+A Sbjct: 740 TTMWVAKSAPLAAGSGPPGIGSPVDGAALFVLDAWLRPVPPGVVGELYVAGSGVGVGYLG 799 Query: 1880 XXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQA 1939 LTG+RFVACPFG G RMYRTGDLV W DGQL+Y+GRADEQVKIRGYRIELGEI + Sbjct: 800 RAGLTGSRFVACPFGGAGTRMYRTGDLVWWDPDGQLRYVGRADEQVKIRGYRIELGEIHS 859 Query: 1940 ALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLET 1999 AL + GV+QA V+AREDRPGD+RLVGYITGTADPA R+ L RLP YMVPAA+V L Sbjct: 860 ALMGLAGVEQAAVVAREDRPGDRRLVGYITGTADPAEVRARLGERLPGYMVPAAIVALPE 919 Query: 2000 LPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXX 2059 LP+T+NGKLD RALPAPEY + YRAP T TE+ LAGI++ VLG+ER Sbjct: 920 LPVTLNGKLDTRALPAPEY-LGRGYRAPATFTEEVLAGIYSQVLGLERVGVDDSFFDLGG 978 Query: 2060 XXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRV 2108 AMR+ AAVN LD LSVR LFEAPT+ +L+ ++ G R RV Sbjct: 979 DSLSAMRLVAAVNARLDVALSVRALFEAPTIRRLAPRLD-GGGARLARV 1026 Score = 695 bits (1793), Expect = 0.0 Identities = 437/973 (44%), Positives = 571/973 (58%), Gaps = 66/973 (6%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+P T+ + S D+LDE EH ++ V GNRAVL P V+IP LFA QV RAPDAVA+ Sbjct: 1471 VTADP-TKRISSIDVLDEAEHARLAVVGNRAVLHGPSRAGVSIPELFAAQVDRAPDAVAI 1529 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RSWTY ELDE SNRLAH+L E+GA PG VA L RS +A+ ++L+VLKTGAAYLP Sbjct: 1530 TCAQRSWTYGELDETSNRLAHLLIEYGAGPGECVALLAERSAQAVAAMLAVLKTGAAYLP 1589 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP P ARI F++ DA P+AA+ T +RSRLD DL +D+ DPA+ + +D LS P Sbjct: 1590 IDPGLPAARIEFLLGDAAPIAAIVTPGMRSRLDGSDLTALDVDDPAVATQSTDGLSPPDA 1649 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 +++AY+ YTSGTTGVPK VAVTHHNVTQL+ ++ + G +VWSQ HSL FD SVWEI Sbjct: 1650 ENVAYVIYTSGTTGVPKGVAVTHHNVTQLLESVDREFELG--RVWSQCHSLAFDFSVWEI 1707 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEG--LESTTLIV 298 +GALL G RLV+VP+ V SP+DLH +L+ E+VSVL QTPSA LSPE L+ T++ Sbjct: 1708 FGALLRGARLVIVPDDVVRSPEDLHAMLVRERVSVLSQTPSAFYALSPEPSELKLQTVVF 1767 Query: 299 AGEACPTELVDRWAPGRV----MINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXL 354 GEA + RW R +IN YG TE T++A+ E L Sbjct: 1768 GGEALEPPRLGRWLHNRPKLPRLINMYGITETTVHASFREITEADVGDTTSPIGAPLAHL 1827 Query: 355 --FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDL 412 FVLD+WL P P GV GELYVAG GVA GY GR LTASRFVACPFG G RMYRTGDL Sbjct: 1828 GFFVLDEWLHPVPAGVTGELYVAGGGVACGYGGRAGLTASRFVACPFGAFGSRMYRTGDL 1887 Query: 413 VRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVG 472 VRWG+DG+L+YLGRADEQVKIRGYRIELGEI+AAL D V+QA V+AREDRPGDKRLV Sbjct: 1888 VRWGADGRLQYLGRADEQVKIRGYRIELGEIRAALTAFDEVEQAAVVAREDRPGDKRLVA 1947 Query: 473 YITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYR 532 Y+TGTADPA +R LA+ LP YMVP AVV +D IPLT+NGKLD RALPAP+Y+ +YR Sbjct: 1948 YVTGTADPAHVRARLADRLPGYMVPAAVVAVDAIPLTLNGKLDTRALPAPDYQE-GGEYR 2006 Query: 533 APSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCR--PRDI 590 AP+TP E+ILA +YA+VLG+ERVGV++SFFDLGGDS+ +M++VA A A G+ R R + Sbjct: 2007 APATPVEEILAGIYARVLGLERVGVEESFFDLGGDSLSAMRLVA-AAATGLDARLEVRTL 2065 Query: 591 FVEQT-XXXXXXXXXXXXESHVVDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVIT 644 F T + V G P V A + + ++ GP+ +N Sbjct: 2066 FEAPTIRQLAPRLGAGGGRAARVVAGARPAVVPLSFAQSRLWFTGQLQGPSPVYNMAAAM 2125 Query: 645 QAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA 704 + V + + L ++ RH +LR V ++ T + ++ E G R VDA Sbjct: 2126 RLDGRVDVEALRAALGDVVARHESLR-TVFMARKGTPQQVVVPAERADFG----WRVVDA 2180 Query: 705 -------LTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILL 754 L + + A + D A + A R + LV + HH+A DG S + L+ Sbjct: 2181 LGWPASRLDEAIEAAAHHPFDLANEVPLRAKLFRVDANRHVLVAVAHHIAADGSSLKPLV 2240 Query: 755 EDLNIAWAQHCTGQS---IELPAGGTSFARW-SALLAEHAKTDTVRDLADAWR----AVT 806 DL +A+A C G + LP + W A L + D +A R A+ Sbjct: 2241 ADLGLAYASRCAGHAPPWAPLPVQYIDYTLWQQARLGD--LDDPGSPIAGQLRYWQHALA 2298 Query: 807 SVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRA-GVQDILLVAFGLA-- 863 +P+ L + D A AS+ V+ ++ V A RA +++ GLA Sbjct: 2299 GLPERL-ALPTDRPYPAVADHRGASVSVDWPAEVQQRVREAARAHNATSFMVIQAGLAVL 2357 Query: 864 WTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGD 923 + SD +G + G D L VG+F V L +AG+ Sbjct: 2358 LAKVSATSDVAVGFPIAGR-------PDPALDELVGFF---------VNTLVLRVDLAGN 2401 Query: 924 AALGGIVKAVKEQ 936 L ++ V+++ Sbjct: 2402 PTLAEVLAQVRQR 2414 Score = 694 bits (1791), Expect = 0.0 Identities = 435/952 (45%), Positives = 565/952 (59%), Gaps = 81/952 (8%) Query: 3 AEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVS 62 AE R L S D+LDE EH ++EV GN A L+ P P ++IP LF V R+PDAVA+ Sbjct: 6109 AEEPGRRLSSIDVLDEAEHARLEVVGNHAALSRPTPAGLSIPQLFTASVNRSPDAVAINC 6168 Query: 63 GDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVD 122 GDRSWTY + D A+NRLAH+L EHGA PG VA LIPRS A+ ++L+VLK+GAAY+P+D Sbjct: 6169 GDRSWTYGQFDVAANRLAHLLIEHGAGPGERVALLIPRSAGAVAAMLAVLKSGAAYVPID 6228 Query: 123 PAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDD 182 P P ARI FM+SD+ PVA LTT+ LRSRLD L V+++ DP +D P AL PRP+D Sbjct: 6229 PGLPAARIAFMLSDSAPVAVLTTSGLRSRLDGCGLPVLEIDDPVVDTLPGTALPPPRPED 6288 Query: 183 LAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWG 242 +AY+ YTSGTTG+PK VAVTH NV QL+ +L +L G QVW+Q HSL FD SVWEI+G Sbjct: 6289 VAYIIYTSGTTGIPKGVAVTHRNVAQLLDSLDDELELG--QVWTQCHSLAFDFSVWEIFG 6346 Query: 243 ALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPE---GLES 293 ALL GGRLVVV ++V SP++L+ LL+ E+VSVL QTPSA A L+P+ L+ Sbjct: 6347 ALLRGGRLVVVSDAVVRSPEELYALLVREQVSVLSQTPSAFDALQTADALAPDLAQQLKL 6406 Query: 294 TTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSEPLXXXXXXXXXXXXX 349 TL+ GEA + RW PG +IN YG TE T++A+ E Sbjct: 6407 QTLVFGGEALEARRLGRWLDNHPGLPRLINMYGTTETTVHASFRELGAGDVGGDASPIGG 6466 Query: 350 XXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMY 407 L FVLD+WLRP P GVVGEL+VAG G+A GY+GR LT SRFVACP G G+RMY Sbjct: 6467 PLAHLAFFVLDRWLRPVPAGVVGELFVAGRGLACGYVGRSGLTGSRFVACPSGPPGQRMY 6526 Query: 408 RTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGD 467 RTGDLVRWG+DGQL YLGRAD+QVKIRG+RIELGEI L L GV +A VIAREDRPGD Sbjct: 6527 RTGDLVRWGADGQLRYLGRADDQVKIRGHRIELGEIHTVLTGLAGVKRAAVIAREDRPGD 6586 Query: 468 KRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSA 527 KRLVGY+TG+ADPA +R ALAE LPAYMVP+AVVV+D IPLTVNGKLD RALPAP+YR A Sbjct: 6587 KRLVGYVTGSADPAAIRAALAERLPAYMVPSAVVVVDAIPLTVNGKLDTRALPAPDYRGA 6646 Query: 528 ANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCR 586 A YRAP+T E+ILA +YA+VLG++RVGVDDSFFDLGGDS+ +M+++A A Sbjct: 6647 A-PYRAPATATEEILAGIYARVLGIDRVGVDDSFFDLGGDSLAAMRLIAAVNAGLNAHLG 6705 Query: 587 PRDIFVEQTXXXXXXXXXXXXESHVVDEGVGPVVATPI------MRWLREVDGPTGQFNQ 640 R +F T + P+ + +L ++ GP+ +N Sbjct: 6706 VRSLFEAPTIHLLAPRLGADGAGRTPLVAIERPAVIPLSFAQSRLWFLDQLQGPSAVYNM 6765 Query: 641 TVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR 700 + + + L ++ RH +LR V E T + ++VP A A A + Sbjct: 6766 AAALRLRGSLDVGALGAALGDVVARHESLR-TVFVAAEGTPQ-QIVVPPAEADVAYD--- 6820 Query: 701 TVDA-------LTDDVLVEARNRLDPAAGAMVSAVWVRETS----QLVLMIHHLAVDGVS 749 VDA L + V A D + A W+ T+ LV ++HH+A DG+S Sbjct: 6821 VVDATAWPPGRLAEAVEAVAHYAFDLGTEIPLRA-WLFRTAGDEHVLVSVLHHIAADGLS 6879 Query: 750 WRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHA-----KTDTVRDLADA--- 801 L+ DL +A+A+ C G+ P G W+ L ++A + D DL D Sbjct: 6880 LTPLVRDLGVAYARRCAGE----PPG------WAPLAVQYADYTLWQRDQFGDLDDPDSP 6929 Query: 802 -------W-RAVTSVPQALPPVQPDTDTY-VTAGQLSASLDVE---TTRQLLGEVPAAFR 849 W + +P+ L V P Y + A A++ V+ +Q + EV A Sbjct: 6930 IAGQLRFWEHNLAGMPERL--VLPTDRPYPLVADHRGATVSVQWPAELQQRVREVARAHN 6987 Query: 850 AGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 A ++ A + + S+ +G + GR D + DV VG+F Sbjct: 6988 ATSFMVVQAALAVLLSTLSGSSEVAVGFPIA--GRRDPVLDDV-----VGFF 7032 Score = 681 bits (1758), Expect = 0.0 Identities = 416/933 (44%), Positives = 530/933 (56%), Gaps = 55/933 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+ +TR LLS D+LDE + ++ WGN AV+ P TIP F Q R+P AVA+ Sbjct: 417 LTAD-TTRRLLSIDVLDEADRVRLAGWGNWAVMGRAAPAGRTIPEWFGVQAGRSPSAVAI 475 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 R W+YRE+DEASNRLA L G A V L+ RS EA++++L VLK GAAY+P Sbjct: 476 SCEGRRWSYREVDEASNRLARWLIGRGVGRRARVGLLMERSAEAVIAVLGVLKAGAAYVP 535 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP P R+ FM++DA P A + +A LR RL ++ V D+ DP I ++P+ ++GP Sbjct: 536 MDPGLPAGRVEFMLADAAPAAVIVSAGLRPRLGEFAGVVADVDDPVIRQQPAAGVAGPSA 595 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+A++ YTSGTTGVPK VAVTH NVTQL AL D GQVWSQ HSL FD SVWEI Sbjct: 596 DDVAHVIYTSGTTGVPKGVAVTHRNVTQLFEALAGDGLLSAGQVWSQCHSLAFDFSVWEI 655 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGG LVVVP+++ D+L LL+ ++VSVL QTPS+ G LSP+G+ L+V Sbjct: 656 WGALLHGGHLVVVPDALTRRADELRALLVGQRVSVLTQTPSSLGALSPDGV-GAALVVGA 714 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP ++VDRWAPGR M+N YGPTE T++ A S PL LFVLD W Sbjct: 715 EACPAQVVDRWAPGRAMVNVYGPTETTMWVAKSAPLAAGSGPPGIGSPVDGAALFVLDAW 774 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELYVAG GV GY+GR LT SRFVACPFG G RMYRTGDLV W DGQ Sbjct: 775 LRPVPPGVVGELYVAGSGVGVGYLGRAGLTGSRFVACPFGGAGTRMYRTGDLVWWDPDGQ 834 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L Y+GRADEQVKIRGYRIELGEI +AL L GV+QA V+AREDRPGD+RLVGYITGTADP Sbjct: 835 LRYVGRADEQVKIRGYRIELGEIHSALMGLAGVEQAAVVAREDRPGDRRLVGYITGTADP 894 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A++R L E LP YMVP A+V L +P+T+NGKLD RALPAPEY YRAP+T E+ Sbjct: 895 AEVRARLGERLPGYMVPAAIVALPELPVTLNGKLDTRALPAPEY--LGRGYRAPATFTEE 952 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGIQCRPRDIFVEQTXXXX 599 +LA +Y+QVLG+ERVGVDDSFFDLGGDS+ +M++VA A + R +F T Sbjct: 953 VLAGIYSQVLGLERVGVDDSFFDLGGDSLSAMRLVAAVNARLDVALSVRALFEAPTIRRL 1012 Query: 600 XXXXXXXXESHV-VDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTED 653 V G P V A + +L ++ G + N V + + D Sbjct: 1013 APRLDGGGARLARVVAGARPEVVPLSFAQSRLWFLDQLHGCSPVHNMAVALRLRGRLDAD 1072 Query: 654 DVVVILQALLDRHATLR---LRVEDTQEDT------DEWSLLVPEAGAVGARECLRTVDA 704 + ++ RH +LR + E T ++ V +AG +DA Sbjct: 1073 VLGTAFADVVARHESLRTVFVAPEGTPRQVVVPAAHADFGWQVVDAGGWPGARLAEAIDA 1132 Query: 705 -------LTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDL 757 LT ++ + A+ AG V LV + HH+A DG S L+ DL Sbjct: 1133 VAHQPFDLTTEIPLRAK-LFRVGAGEHV----------LVAVAHHIAADGWSITPLVRDL 1181 Query: 758 NIAWAQHCTGQS---IELPAGGTSFARWSALL---AEHAKTDTVRDLADAWRAVTSVPQA 811 IA+A C G ELP + W E + LA A+ +P+ Sbjct: 1182 GIAYASRCAGAPPGWAELPVQYVDYTLWQRAQFGDLEDPHSAITAQLAYWLDALAGMPER 1241 Query: 812 LPPVQPDTDTYVTAGQLSASLDVE---TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFL 868 L + D A A + VE +Q + EV A ++ A L + Sbjct: 1242 L-EMPTDRPYPSVADYRGARVAVEWPPELQQRVSEVAGEHNATSFMVVQTALALLLAKLG 1300 Query: 869 NRSDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 SD +G + G D L VG+F Sbjct: 1301 ATSDVAVGFPIAGR-------RDPALDELVGFF 1326 >tr|A5A9R4|A5A9R4_MYCCH Tax_Id=1774 (mps1)SubName: Full=MPS1 protein;[Mycobacterium chelonae] Length = 3458 Score = 2542 bits (6588), Expect = 0.0 Identities = 1328/2135 (62%), Positives = 1571/2135 (73%), Gaps = 53/2135 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P R L S + L DE + GNRAVL P + V+IP LF QV P+A AL Sbjct: 422 MAADPDRR-LSSLNSLVNDELTSLAEVGNRAVLAGPVASRVSIPELFFSQVAADPEAPAL 480 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G+R+ TYRELDEA+N L+ L G PG V L RS +A++ IL+VLK GAAYLP Sbjct: 481 TFGERTLTYRELDEAANALSGQLVSQGVGPGDRVVLLSDRSAQAVIGILAVLKAGAAYLP 540 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P +R+ F++ DA P AA+TTA LR+RLD +DL +ID+ A P+ SG RP Sbjct: 541 IDPAVPASRLEFIVGDAAPAAAITTAGLRARLDGFDLPIIDLDASAAGTEPTAPASGARP 600 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTHHNVTQL+S+L A LP+ PG VW HSL FDVSVWEI Sbjct: 601 DDIAYIIYTSGTTGAPKGVAVTHHNVTQLMSSLDAGLPN-PG-VWPLCHSLAFDVSVWEI 658 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WG LL GGRLVVVPES+ SP + H++L+ E+V+VL QTPSA MLSPEGLEST L V G Sbjct: 659 WGPLLRGGRLVVVPESITGSPAEFHDVLVAEQVTVLTQTPSAVAMLSPEGLESTALAVVG 718 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX--LFVLD 358 EACP +V+RWAPGRVMINAYGPTE T+ A+S PL LFVLD Sbjct: 719 EACPASVVERWAPGRVMINAYGPTETTMCVAISAPLVAGAPDSAVPIGAPVPGAALFVLD 778 Query: 359 KWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSD 418 W++P P GVVGELYVAG GVA GYIGR DLTASRFVACPFG+ G RMYRTGDLV WG D Sbjct: 779 TWMQPVPAGVVGELYVAGEGVACGYIGRSDLTASRFVACPFGQPGTRMYRTGDLVSWGDD 838 Query: 419 GQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA 478 GQL+YLGRADEQVKIRGYRIELGE+QAAL+ LDGVD A I REDRPGDKRLVGY+TGT Sbjct: 839 GQLQYLGRADEQVKIRGYRIELGEVQAALSALDGVDHAAAIVREDRPGDKRLVGYVTGTV 898 Query: 479 DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPA 538 DPA++R+ LA+ LP YMVP AVVVL+ +PLT N KLD RALP PEY DYRAP T Sbjct: 899 DPAEVRSTLAKRLPPYMVPAAVVVLEALPLTSNNKLDTRALPTPEYGGLGADYRAPGTAV 958 Query: 539 EQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXX 598 E+IL VYAQVLGV+RVGVDDSFFDLGGDSILSMQVVARARAAG+ CRPRD+F+EQT Sbjct: 959 EEILVGVYAQVLGVDRVGVDDSFFDLGGDSILSMQVVARARAAGVLCRPRDVFIEQTVSR 1018 Query: 599 XXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTG---QFNQTVITQAPAGVTEDD 654 E+ VVDEG+GPV TPIM WLR G +FNQT++ QAPA V+EDD Sbjct: 1019 LAAVVEISGGEADVVDEGLGPVEVTPIMHWLRGAQDSAGAIDEFNQTLVVQAPAAVSEDD 1078 Query: 655 VVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEAR 714 VVV+LQALLDRH TLRLR D + EWSLLVPE GA+ AR+CLR +DAL+ + LV AR Sbjct: 1079 VVVVLQALLDRHPTLRLRATD---NAGEWSLLVPEVGAIDARDCLRVIDALSGETLVAAR 1135 Query: 715 NRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPA 774 +RL+PA GAM+SA WV +T QLVL+IHHLA+DGVSWRILLEDLNIAWAQH +G + LP Sbjct: 1136 SRLNPATGAMLSAAWVPDTKQLVLVIHHLAIDGVSWRILLEDLNIAWAQHHSGADVVLPV 1195 Query: 775 GGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDV 834 GGTSFARWS+LL+EHA++ V ADAW+ V + P +P VQP TDTY AG+LS SLD Sbjct: 1196 GGTSFARWSSLLSEHARSTEVVAQADAWKEVLTAPAHVPAVQPTTDTYANAGRLSLSLDA 1255 Query: 835 ETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDV-- 892 ETTR LLGEVPAAF AGVQDILL+AFGLAW EFL PI D+EGHGR +E+ V Sbjct: 1256 ETTRHLLGEVPAAFHAGVQDILLIAFGLAWNEFLGAGGAPIAFDIEGHGRQEEIGEAVHR 1315 Query: 893 --DLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLR 950 DLSRTVGWFTTKYP +L V L W QV AG++AL ++KA KEQLR+LP+GLTYGLLR Sbjct: 1316 RIDLSRTVGWFTTKYPASLAVGELSWAQVTAGESALSHVIKAAKEQLRALPDGLTYGLLR 1375 Query: 951 YLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVE 1010 YLN ++ L GS+PTIGFNYLGRLGAGA ELSE+ WRID + MPL H+VE Sbjct: 1376 YLNTDIGLDGSEPTIGFNYLGRLGAGAAELSEDFWRIDHESLSLTDVAAAISMPLAHSVE 1435 Query: 1011 LNAGTIDT----DNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLT 1066 LNAG ++T ++GP LRA+WTWAPSA D+ QA RLSRLWFEAL+GICAHVR GGGGLT Sbjct: 1436 LNAGIVETNSDAESGPELRANWTWAPSALDDAQAARLSRLWFEALSGICAHVRSGGGGLT 1495 Query: 1067 PSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGD----DVYAVQLD 1122 PSD+APARLTQ+QID L Q+Y+VTDVLPLTP+QQGLLF + FA GD DVY+VQL Sbjct: 1496 PSDLAPARLTQQQIDALVQQYEVTDVLPLTPLQQGLLFQAGFAEATGDSAEDDVYSVQLG 1555 Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 +T+TG L+ RLRDAV+ VV RHPNLAARF E++GEPVQ++ A+P+IAW++ +L GD Sbjct: 1556 LTVTGPLNASRLRDAVYAVVKRHPNLAARFSEEYGEPVQIIPAEPVIAWQHAELVGD--- 1612 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSG----NQHRFVLTFHHIVIDGWSLPIL 1238 D ++EQLCAAER+AVC + P FRA LI G ++HR VLT HHIVIDGWSLPIL Sbjct: 1613 VDQQVEQLCAAERAAVCQIFTEPVFRATLISGLGGPAESRHRLVLTAHHIVIDGWSLPIL 1672 Query: 1239 LQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPR 1298 LQEIF Y+G RLP+ APYRNFV WL W LDGFETPTLV G R Sbjct: 1673 LQEIFGAYYGQRLPSPAPYRNFVTWLAAQDRVAAQRAWGVALDGFETPTLVGSLASSGRR 1732 Query: 1299 GIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADL 1358 G ESYR+S + +RAL ELAR+Q TT+NTVLQAAW Q+L +TGQ DVAFGTAVSGRP+DL Sbjct: 1733 GSESYRLSEQISRALSELARAQRTTVNTVLQAAWAQVLTWLTGQHDVAFGTAVSGRPSDL 1792 Query: 1359 AGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQL 1418 GAESMVGLLINTVP+RA ++A TTV DLL QLQ HNDT+EHEHLALN+IHH G ++L Sbjct: 1793 VGAESMVGLLINTVPVRANINAATTVADLLDQLQRAHNDTVEHEHLALNEIHHAVGLDRL 1852 Query: 1419 FDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFD 1478 FDTLF+YE+YPID A +GVQELA+T+F++REYNHYPLSV+A+PGHELGLRVE+DT VF+ Sbjct: 1853 FDTLFVYENYPIDVGAQLGVQELAITDFSSREYNHYPLSVVAMPGHELGLRVEFDTDVFE 1912 Query: 1479 VSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIP 1538 ++ IE ++DRF+++L AMI DPA RLSS+D++D E +LD W NRAVLT+P + SIP Sbjct: 1913 LAAIEIIVDRFRQVLTAMIADPATRLSSIDLLDAGEHDRLDTWGNRAVLTRPELALTSIP 1972 Query: 1539 EVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADA 1598 E+FA QV R PEA A+T S +YGELD AN+LAN L GA PG+ VAL++PR+ +A Sbjct: 1973 ELFAAQVMRAPEAIAITCGERSWSYGELDATANRLANHLVSRGAGPGERVALLLPRTGEA 2032 Query: 1599 IVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDD 1658 I AILAVLKTGAAYLPIDP+ P +R+EF+LGDA P+AAVTT DL R + V+++D Sbjct: 2033 IAAILAVLKTGAAYLPIDPAHPDSRVEFVLGDAAPIAAVTTADLLPRLGASGIPAVDIND 2092 Query: 1659 PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAV 1718 PAV+ L P+ DDIAY+IYTSGTTG PKGVA+TH NV Q+L++L AEL G V Sbjct: 2093 PAVDRQSDVALPVPAVDDIAYIIYTSGTTGAPKGVAVTHRNVAQLLESLDAELDL--GQV 2150 Query: 1719 WSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA-- 1776 W+Q HSL FD SVWEIWGALL+GGRL+IVP+++ SP+DLHA+LVSE V+VL QTPSA Sbjct: 2151 WTQCHSLAFDYSVWEIWGALLYGGRLLIVPDAVVRSPEDLHAMLVSEQVSVLSQTPSAFY 2210 Query: 1777 ----VRMMSPE---GLEGTALVVAGEACPTEVVDRWAVDRV----MINAYGPTESTIYAA 1825 M PE L+ +V GEA + + W MIN YG TE+T++A+ Sbjct: 2211 ALQTADAMQPEVGQQLKLQTVVFGGEALEPQRLSPWFDSHPGLPRMINMYGITETTVHAS 2270 Query: 1826 ISAPLSPGSDVV--PIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXL 1883 S D PIG P+ A FVLD WLR VP GVVGELY+A L Sbjct: 2271 FREIGSGDVDSTSSPIGVPLEHLAFFVLDGWLRQVPVGVVGELYVAGSGQASGYLGRSDL 2330 Query: 1884 TGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSD 1943 T TRFVACPFG PG+RMYRTGDLV+WG+DGQL+Y+GRAD+QVKIRGYRIELGE+ AAL+ Sbjct: 2331 TTTRFVACPFGAPGSRMYRTGDLVQWGEDGQLRYVGRADKQVKIRGYRIELGEVHAALAR 2390 Query: 1944 VDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTNRLPAYMVPAAVVTLET 1999 V+GVDQA VIAREDRPGDKRLVGYIT GT DPAA R+ L RLPAYMVPAAVV L Sbjct: 2391 VEGVDQAAVIAREDRPGDKRLVGYITESTKGTLDPAAVRAVLAERLPAYMVPAAVVVLGA 2450 Query: 2000 LPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXX 2059 +PLTVNGKLD RALPAPEYQ A YRAPE E+ LAGI+A VLGVE+ Sbjct: 2451 MPLTVNGKLDTRALPAPEYQDADHYRAPEDAVEEILAGIYAQVLGVEQIGVDDSFFDLGG 2510 Query: 2060 XXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +M+V A A L R +F TV++L+ Sbjct: 2511 DSISSMQVVARARAA-GLLLRPRDIFVEQTVSRLA 2544 Score = 1863 bits (4825), Expect = 0.0 Identities = 956/1528 (62%), Positives = 1144/1528 (74%), Gaps = 37/1528 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P+TR L S DLLD EHD+++ WGNRAVLT P +IP LFA QV+RAP+A+A+ Sbjct: 1930 MIADPATR-LSSIDLLDAGEHDRLDTWGNRAVLTRPELALTSIPELFAAQVMRAPEAIAI 1988 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G+RSW+Y ELD +NRLA+ L GA PG VA L+PR+GEAI +IL+VLKTGAAYLP Sbjct: 1989 TCGERSWSYGELDATANRLANHLVSRGAGPGERVALLLPRTGEAIAAILAVLKTGAAYLP 2048 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPAHPD+R+ F++ DA P+AA+TTADL RL + +D+ DPA+DR+ AL P Sbjct: 2049 IDPAHPDSRVEFVLGDAAPIAAVTTADLLPRLGASGIPAVDINDPAVDRQSDVALPVPAV 2108 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH NV QL+ +L A+L G QVW+Q HSL FD SVWEI Sbjct: 2109 DDIAYIIYTSGTTGAPKGVAVTHRNVAQLLESLDAELDLG--QVWTQCHSLAFDYSVWEI 2166 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA------AGMLSPE---GL 291 WGALL+GGRL++VP++V SP+DLH +L++E+VSVL QTPSA A + PE L Sbjct: 2167 WGALLYGGRLLIVPDAVVRSPEDLHAMLVSEQVSVLSQTPSAFYALQTADAMQPEVGQQL 2226 Query: 292 ESTTLIVAGEACPTELVDRWA---PGRV-MINAYGPTEATIYAAMSEPLXXXXXXXXXXX 347 + T++ GEA + + W PG MIN YG TE T++A+ E Sbjct: 2227 KLQTVVFGGEALEPQRLSPWFDSHPGLPRMINMYGITETTVHASFREIGSGDVDSTSSPI 2286 Query: 348 XXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 L FVLD WLR P GVVGELYVAG G A+GY+GR DLT +RFVACPFG G R Sbjct: 2287 GVPLEHLAFFVLDGWLRQVPVGVVGELYVAGSGQASGYLGRSDLTTTRFVACPFGAPGSR 2346 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLV+WG DGQL Y+GRAD+QVKIRGYRIELGE+ AALA+++GVDQA VIAREDRP Sbjct: 2347 MYRTGDLVQWGEDGQLRYVGRADKQVKIRGYRIELGEVHAALARVEGVDQAAVIAREDRP 2406 Query: 466 GDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPA 521 GDKRLVGYIT GT DPA +R LAE LPAYMVP AVVVL +PLTVNGKLD RALPA Sbjct: 2407 GDKRLVGYITESTKGTLDPAAVRAVLAERLPAYMVPAAVVVLGAMPLTVNGKLDTRALPA 2466 Query: 522 PEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA 581 PEY+ A + YRAP E+ILA +YAQVLGVE++GVDDSFFDLGGDSI SMQVVARARAA Sbjct: 2467 PEYQDA-DHYRAPEDAVEEILAGIYAQVLGVEQIGVDDSFFDLGGDSISSMQVVARARAA 2525 Query: 582 GIQCRPRDIFVEQTXXXXXXXXXXXX-ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQ 640 G+ RPRDIFVEQT E+ VVD G GPVVATPI+RWL + G +FNQ Sbjct: 2526 GLLLRPRDIFVEQTVSRLAQVAVFADGETAVVDAGTGPVVATPIIRWLHGLGGKVDEFNQ 2585 Query: 641 TVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR 700 TV+ QAP GV +DDVV +LQALLDRHATLRLR ED+ EWSLLVPE G V ARECL Sbjct: 2586 TVVLQAPEGVADDDVVTVLQALLDRHATLRLRAEDSD---GEWSLLVPETGTVDARECLL 2642 Query: 701 TVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIA 760 VD LTD+ L +AR+RL+PA+G+M+SA+W R +S+LVL++HHLAVD VSWRILLEDLNI Sbjct: 2643 AVDVLTDEALRQARSRLNPASGSMLSALWERGSSRLVLIVHHLAVDAVSWRILLEDLNIG 2702 Query: 761 WAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTD 820 WAQH GQ +ELP GGTSFARW+ LL +HA+ V LADAWR V ++P ALP P D Sbjct: 2703 WAQHHGGQPVELPPGGTSFARWATLLDQHARAADVVALADAWRQVEAIPAALPAAHPTMD 2762 Query: 821 TYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVE 880 TY +AGQLS SLD + TR+LLGEVPAA+ AGVQDILL+AF LAW EFL + PIG+DVE Sbjct: 2763 TYASAGQLSVSLDADLTRELLGEVPAAYHAGVQDILLIAFALAWNEFLGSNGAPIGIDVE 2822 Query: 881 GHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSL 940 GHGR +E A D DLSRTVGWFT+KYPV+L V L W VVAG++AL I+K KEQLR+L Sbjct: 2823 GHGRQEEFAGDADLSRTVGWFTSKYPVSLAVGELSWAHVVAGNSALAPIIKDAKEQLRAL 2882 Query: 941 PEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXX 1000 P+GLTYGLLRYLNP+ +GG DP IGFNYLGRLGAG +LSE+LWRID Sbjct: 2883 PDGLTYGLLRYLNPDAGVGGPDPAIGFNYLGRLGAGGADLSEDLWRIDPDGVSITAAATS 2942 Query: 1001 VPMPLMHTVELNAGTID---TDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAH 1057 VP PL HTVELNAG ++ D+G L A+WTWA SA +Q R+SRLWF+ALAGIC+H Sbjct: 2943 VPTPLGHTVELNAGVMEGAGPDSG-RLHATWTWALSALSHDQVDRISRLWFDALAGICSH 3001 Query: 1058 VRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGI---GD 1114 VR GGGGLTPSDVAPARL+Q QID+L ++Y + DVLPLTP+QQGLLFHS A D Sbjct: 3002 VRSGGGGLTPSDVAPARLSQSQIDQLHEQYQIADVLPLTPLQQGLLFHSNLAPEAMDGSD 3061 Query: 1115 DVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYL 1174 D+YAVQLD+ ++G LD RL++AVHT + R PN+ A F E+FGEP+Q++ A P +AW+Y+ Sbjct: 3062 DLYAVQLDVALSGPLDPKRLQEAVHTAITRRPNVVATFYEEFGEPIQLIPAAPELAWQYI 3121 Query: 1175 DLRGD-DLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGW 1233 + D L + ++++L AAER+AVCDL +P FRAAL RT +Q+RFVLT HHIV+DGW Sbjct: 3122 EFDADGGLDVEQQVDRLSAAERAAVCDLAGQPAFRAALARTGEDQYRFVLTNHHIVLDGW 3181 Query: 1234 SLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG 1293 S PILLQEIFA YFG RLPA YR FV WL WR+V +GFETPTLV PPG Sbjct: 3182 SKPILLQEIFASYFGERLPAPVSYRRFVTWLAAQDNSSARSAWRDVFEGFETPTLVGPPG 3241 Query: 1294 --VPGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAV 1351 V G RG+ES+ VSAETT+ALGELARS TT++TVLQAAW QLLM +TGQ DVAFGTAV Sbjct: 3242 RIVLGRRGVESFEVSAETTQALGELARSCRTTVSTVLQAAWAQLLMWLTGQNDVAFGTAV 3301 Query: 1352 SGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHH 1411 SGRP+DL GAESMVGLLINTVP+RA ++ TT+ DLL QLQ + DTLEH+HLALN+IHH Sbjct: 3302 SGRPSDLVGAESMVGLLINTVPVRATITPTTTIADLLNQLQGAYGDTLEHQHLALNEIHH 3361 Query: 1412 VSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVE 1471 GH+QLFDT+F+YE+YPIDT+A V EL++T F+NREYNHYPL+V A PGHELGLRVE Sbjct: 3362 AVGHDQLFDTMFVYENYPIDTAALSRVHELSITGFSNREYNHYPLAVQATPGHELGLRVE 3421 Query: 1472 YDTSVFDVSEIETLIDRFQRLLEAMIDD 1499 +DT VF+ I L+ RFQR+LEAM D Sbjct: 3422 FDTDVFNAVRIGKLVKRFQRVLEAMTSD 3449 Score = 731 bits (1886), Expect = 0.0 Identities = 457/1003 (45%), Positives = 578/1003 (57%), Gaps = 32/1003 (3%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 + I G +++ L AV + A F+E G+ VQ + + D+R D Sbjct: 37 VRIEGKVERVLLEQAVRQAINEAEPARAAFLEVNGQIVQRAIDHSELVLDFHDVR-DSED 95 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 P Q+ ++ + + L ++ + ALIRT+ +Q+ HHI +DG + I+ + I Sbjct: 96 PVEHARQIASSIQRTLMPLTDQ-LLKFALIRTADDQYYMFGLCHHINLDGLGMAIVSRRI 154 Query: 1243 FAGYF----GHRLPAA--APYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVP- 1295 + Y G +P A ++ V+ RE P P P Sbjct: 155 ASIYSALVAGDPVPDAYFGTLQDLVDLEAEYEASTDYTEDREYWSRNLPPDSGLDPRPPH 214 Query: 1296 GPRGIESYRVSAETT---RALGE---LARSQHTTINTVLQAAWTQLLMR--MTGQRDVAF 1347 G E Y +A +GE L ++ +V+ AA LL+R T +VA Sbjct: 215 AHEGHEGYTPTASVQIDDTVVGEIKDLTKALRVRRYSVITAACA-LLVRGWSTSGSEVAL 273 Query: 1348 GTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHE----H 1403 VS R ++++ G+L VP+ ++TV + + + + L+H+ H Sbjct: 274 DFPVSRRVRP--ESKTLPGMLAGVVPLVLSAPPESTVAEFCQHVDVRIRELLKHQRFPAH 331 Query: 1404 LALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPG 1463 + + G Q + + + P+ + + T N+ H+ L + Sbjct: 332 VLDGGEFGLRGPRQAGNRVAI-NFIPMRLTLDLAGVPATATYTNHGPMGHFGLFFIGA-S 389 Query: 1464 HELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWAN 1523 +L L D F + L +R QRLL M DP RRLSS++ + +DE T L E N Sbjct: 390 DQLLLSTSGDGLPFSKFGVPNLTERLQRLLSEMAADPDRRLSSLNSLVNDELTSLAEVGN 449 Query: 1524 RAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAA 1583 RAVL PV S SIPE+F QV DPEAPA+TF +L Y ELDEAAN L+ L G Sbjct: 450 RAVLAGPVASRVSIPELFFSQVAADPEAPALTFGERTLTYRELDEAANALSGQLVSQGVG 509 Query: 1584 PGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLR 1643 PG V L+ RSA A++ ILAVLK GAAYLPIDP+VPA+RLEF++GDA P AA+TT LR Sbjct: 510 PGDRVVLLSDRSAQAVIGILAVLKAGAAYLPIDPAVPASRLEFIVGDAAPAAAITTAGLR 569 Query: 1644 SRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQV 1703 +R DGFDL ++++D A P+ PDDIAY+IYTSGTTG PKGVA+TH NVTQ+ Sbjct: 570 ARLDGFDLPIIDLDASAAGTEPTAPASGARPDDIAYIIYTSGTTGAPKGVAVTHHNVTQL 629 Query: 1704 LDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLV 1763 + +L A LP PG VW HSL FDVSVWEIWG LL GGRLV+VPESI GSP + H +LV Sbjct: 630 MSSLDAGLP-NPG-VWPLCHSLAFDVSVWEIWGPLLRGGRLVVVPESITGSPAEFHDVLV 687 Query: 1764 SEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIY 1823 +E V VL QTPSAV M+SPEGLE TAL V GEACP VV+RWA RVMINAYGPTE+T+ Sbjct: 688 AEQVTVLTQTPSAVAMLSPEGLESTALAVVGEACPASVVERWAPGRVMINAYGPTETTMC 747 Query: 1824 AAISAPLSPGS--DVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXX 1881 AISAPL G+ VPIG+PVP A FVLD W++PVP GVVGELY+A Sbjct: 748 VAISAPLVAGAPDSAVPIGAPVPGAALFVLDTWMQPVPAGVVGELYVAGEGVACGYIGRS 807 Query: 1882 XLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAAL 1941 LT +RFVACPFG+PG RMYRTGDLV WGDDGQLQYLGRADEQVKIRGYRIELGE+QAAL Sbjct: 808 DLTASRFVACPFGQPGTRMYRTGDLVSWGDDGQLQYLGRADEQVKIRGYRIELGEVQAAL 867 Query: 1942 SDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLP 2001 S +DGVD A I REDRPGDKRLVGY+TGT DPA RS L RLP YMVPAAVV LE LP Sbjct: 868 SALDGVDHAAAIVREDRPGDKRLVGYVTGTVDPAEVRSTLAKRLPPYMVPAAVVVLEALP 927 Query: 2002 LTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXX 2060 LT N KLD RALP PEY YRAP T E+ L G++A VLGV+R Sbjct: 928 LTSNNKLDTRALPTPEYGGLGADYRAPGTAVEEILVGVYAQVLGVDRVGVDDSFFDLGGD 987 Query: 2061 XXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 +M+V A A R +F TV++L+ VE GE Sbjct: 988 SILSMQVVARARAA-GVLCRPRDVFIEQTVSRLAAVVEISGGE 1029 >tr|A0QHN3|A0QHN3_MYCA1 Tax_Id=243243 SubName: Full=Syringomycin synthetase;[Mycobacterium avium] Length = 6212 Score = 2541 bits (6587), Expect = 0.0 Identities = 1320/2119 (62%), Positives = 1573/2119 (74%), Gaps = 32/2119 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P+ R + S D+LDE E+ ++ GNRA LT P V+I LFA QV R P+AVA+ Sbjct: 1556 MTADPA-RPVSSIDILDEPEYAHLDALGNRAALTRPATGWVSISQLFAAQVARTPEAVAI 1614 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G+RSWTYRELD ++NRLA VLA GA+PG VA L+PRS A++SIL+VLKTGAAY+P Sbjct: 1615 SCGERSWTYRELDSSANRLARVLAGRGARPGERVAVLVPRSAGAVVSILAVLKTGAAYVP 1674 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP P ARI FM++DA PV +TTA+LR+ D V+ + DPA + P P Sbjct: 1675 IDPGLPSARIDFMLADAVPVVTVTTAELRASAGDPD-RVVAIDDPAPHVPRIGGRAAPAP 1733 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTGVPK VAVTHHNVTQL+ +L L G G+VWSQ HSL FD SVWEI Sbjct: 1734 DDIAYVIYTSGTTGVPKGVAVTHHNVTQLLGSLDDRL--GLGRVWSQCHSLAFDFSVWEI 1791 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALL GGRLV+VP+ V SP+DLH LLI E V+VL QTPSAA LSPE LES L++ G Sbjct: 1792 FGALLRGGRLVIVPDDVVRSPEDLHALLIGEGVTVLSQTPSAAAALSPERLESVALVLGG 1851 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP EL+DRWAPGR+M+N YGPTE T+YA M+ PL LFVLD Sbjct: 1852 EACPVELMDRWAPGRLMVNQYGPTETTLYATMTTPLRAGGAAVPIGSPVPGAALFVLDGR 1911 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LR P GVVGELYVAG GVA GY+GR LTASRFVACPFG TG RMYRTGDL RWG+DGQ Sbjct: 1912 LRRVPPGVVGELYVAGRGVAAGYLGRAALTASRFVACPFGGTGTRMYRTGDLARWGADGQ 1971 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L Y+GRADEQVKIRG+RIELGEI++ LA LDGV+QA VIAR+D G RLV YITGTADP Sbjct: 1972 LHYVGRADEQVKIRGFRIELGEIRSVLAGLDGVEQAAVIARDDGAGHPRLVAYITGTADP 2031 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A+LR LA+ LP YMVP+AVVVLD +PLT NGKLD RALPAP+Y A YRAP E+ Sbjct: 2032 AELRAQLADRLPGYMVPSAVVVLDALPLTGNGKLDTRALPAPDY--AGGRYRAPGDAIEE 2089 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXX 600 ILA +YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG+ C RD+FVEQT Sbjct: 2090 ILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVMCTARDVFVEQTVARLA 2149 Query: 601 XXXXXXX---ESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVV 657 E DEG+GPV TPIMRWL+++DGP +FNQT++ APAGV++ DV V Sbjct: 2150 RVVTVAAADGELGAADEGIGPVQPTPIMRWLQDIDGPIDEFNQTMVLAAPAGVSQSDVAV 2209 Query: 658 ILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRL 717 +LQALLDRH LRL ++D + W L VP G+V AR LRTVD L++ L AR RL Sbjct: 2210 VLQALLDRHPMLRLCLDD--DGAGGWDLHVPPPGSVDARPILRTVDVLSEAALARARARL 2267 Query: 718 DPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGT 777 +P AG M+SAVW ETSQL L++HHLAVDGVSWR L+ED+NIAWAQH +GQ I LP GT Sbjct: 2268 NPGAGLMLSAVWASETSQLALVVHHLAVDGVSWRTLIEDINIAWAQHHSGQEIALPVPGT 2327 Query: 778 SFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETT 837 SFARWS++LAE+AK+ V A AW+ V + P LP V PD DTY +AGQLSASLDV+TT Sbjct: 2328 SFARWSSILAEYAKSPAVVAAAAAWQQVVATPAVLPAVGPD-DTYASAGQLSASLDVQTT 2386 Query: 838 RQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRT 897 R LLGEVPAAF AGVQDILL+AFGLA TEF+ PIG+DVEGHGR++E+AS VDLSRT Sbjct: 2387 RLLLGEVPAAFHAGVQDILLIAFGLACTEFVG-GGAPIGIDVEGHGRHEEIASGVDLSRT 2445 Query: 898 VGWFTTKYPVALTVEN-LPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEV 956 VGWFTTKYPVAL + L W +VVAG+AALG ++K KEQLR+LP+GL+YGLLRYLNPE+ Sbjct: 2446 VGWFTTKYPVALRMSRRLDWARVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEI 2505 Query: 957 DLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTI 1016 ++ G DP IGFNYLGRLG A +LS+E WR+ +P+PL HTVELNAGT+ Sbjct: 2506 EVQGPDPVIGFNYLGRLGGAAADLSDEHWRLSPDSPSVSAAAAAIPLPLGHTVELNAGTM 2565 Query: 1017 DTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLT 1076 DTD GP L A+WTWA S +EQ RLSRLWFEAL GICAHV+ GGGGLTPSD+AP RL Sbjct: 2566 DTDAGPQLHANWTWARSVLTDEQLNRLSRLWFEALTGICAHVQAGGGGLTPSDIAPTRLD 2625 Query: 1077 QRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRD 1136 Q +I++L +RYDV D+LPLTP+QQGLLFH+T + GD VYAVQL +T+ G LD HRL Sbjct: 2626 QGRIEQLERRYDVADILPLTPLQQGLLFHATGSHAEGD-VYAVQLSVTLRGALDPHRLHR 2684 Query: 1137 AVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERS 1196 A+HTVV RHPNLAARF + GEPVQ++ A+P IAWRYL+L D+ D ++EQL A ER+ Sbjct: 2685 ALHTVVTRHPNLAARFCPELGEPVQIIPAEPEIAWRYLELDASDV--DEQLEQLSADERA 2742 Query: 1197 AVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP 1256 AV +L +RP F AALIRT+ +HRFVLT HH+V+DGWSLP+LLQEIFA Y+G RLPA AP Sbjct: 2743 AVRELGDRPPFGAALIRTADTEHRFVLTVHHLVMDGWSLPVLLQEIFACYYGARLPAPAP 2802 Query: 1257 YRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGV--PGPRGIESYRVSAETTRALG 1314 YR FV WL WR VLDGF+TPTLVAP G PG RG+ S+R++AETT A+ Sbjct: 2803 YRGFVTWLAARDVPAARAAWRAVLDGFDTPTLVAPRGADAPGRRGVASFRMAAETTSAVS 2862 Query: 1315 ELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPI 1374 ELAR + TT+NTVLQAAW QLLM +TGQ DVAFGTAVSGRPA+L GAESMVGLLINTVP+ Sbjct: 2863 ELARRRRTTVNTVLQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPV 2922 Query: 1375 RAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSA 1434 RA+ +A TT+ DLL QLQ HNDT+EH+HL LN+IH V+G +QLFDTL +YE+YPIDT+A Sbjct: 2923 RARAAAATTIADLLDQLQCAHNDTVEHQHLGLNEIHRVTGQDQLFDTLLVYENYPIDTAA 2982 Query: 1435 FMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLE 1494 +L TEF+ +YNHYPLS+ +PG ELGLR+E+DT VFD + I+TL DR +RLL Sbjct: 2983 LSAADDLTATEFSCHDYNHYPLSLQVVPGDELGLRLEFDTDVFDPAAIDTLADRLRRLLA 3042 Query: 1495 AMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAV 1554 AM DP R L S+D++D E T+L W NR L++P P S+PE+F QV P A A+ Sbjct: 3043 AMPADPDRPLRSLDLLDSTEHTRLQRWGNRPALSRPATGP-SLPELFTAQVANAPHAVAL 3101 Query: 1555 TFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLP 1614 G S+ Y ELDEA+ +LA+LLA +GA PG VAL+ RSA+AIVA+LAVLKTGAAYLP Sbjct: 3102 RCAGRSMTYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYLP 3161 Query: 1615 IDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSP 1674 IDP++PA R+EFMLGDA PV AV+T LR+R + F L VV+V A P L P+P Sbjct: 3162 IDPALPATRIEFMLGDAAPVVAVSTAGLRARLEAFGLPVVDV--AATGAQPGGPLPPPAP 3219 Query: 1675 DDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEI 1734 D+IAY++YTSGTTGVPKGVA+TH NV Q+L++L A LP G G VWSQ HS FDVSV EI Sbjct: 3220 DNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLP-GTG-VWSQCHSYGFDVSVQEI 3277 Query: 1735 WGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAG 1794 WGAL GGRLV+VPES+ SPD+LHALL++E V VL QTPSA+ +SP L ALV+ G Sbjct: 3278 WGALAGGGRLVVVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLHA-ALVIGG 3336 Query: 1795 EACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEW 1854 E CP + DRWA RVMINAYGPTE+T+ A +S PL+ G+ P+GSPV FVLD W Sbjct: 3337 EPCPAALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDGW 3396 Query: 1855 LRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQ 1914 LRPVP GV GELY+A LT RFVACPFG GARMYRTGDLVRW DG+ Sbjct: 3397 LRPVPAGVTGELYIAGAGVAAGYLGRAGLTAARFVACPFGGAGARMYRTGDLVRWDRDGR 3456 Query: 1915 LQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADP 1974 L Y+ RAD+QVKIRG+RIELGEI +AL+++DGV+QA VIAREDRPG+KR+VGY+TGTADP Sbjct: 3457 LHYVARADQQVKIRGHRIELGEIHSALAELDGVEQAAVIAREDRPGEKRIVGYLTGTADP 3516 Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKT 2034 AA R+ L RLPAYMVPAAV+ +E LPLT NGKLD RALPAPEY + YRAP T TE+ Sbjct: 3517 AAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEY-AGGAYRAPSTPTEEI 3575 Query: 2035 LAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +AGI+ VLG+ R AMRV AAVN LDA LSVR LFEAPT+A+L+ Sbjct: 3576 IAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNAGLDARLSVRVLFEAPTIAQLA 3635 Query: 2095 LHVEHDAGERTDRVSFAAV 2113 + + G R FAAV Sbjct: 3636 ARL-GEGGHR-----FAAV 3648 Score = 1357 bits (3512), Expect = 0.0 Identities = 760/1484 (51%), Positives = 953/1484 (64%), Gaps = 53/1484 (3%) Query: 1116 VYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTA--DPMIAWRY 1173 V+ + + + + G LD A+ VV RH +L F G P Q++ + I W+ Sbjct: 4742 VHNMAIALQLHGRLDAAAFGAALADVVGRHESLRTLFPAHEGIPQQLVIEVDEADIGWQV 4801 Query: 1174 LDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGW 1233 +D G ++ + DL RA L+R +H V HHI DGW Sbjct: 4802 IDASG---WSPARLDDVIRDTARHTFDLAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGW 4858 Query: 1234 SLPILLQEIFAGYFGHR-------LPAAAPYRNFVNWLXXXXXXXXXXX---------WR 1277 SL L++++ Y +P Y ++ W W Sbjct: 4859 SLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLRYWE 4918 Query: 1278 EVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHTTINTVLQAAW 1332 L G E PT P V RG + A+ + + LA + + T V+QAA Sbjct: 4919 SALAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGAHNATSFMVVQAAL 4978 Query: 1333 TQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQ 1390 LL +++ DVA G ++GR PA + +VG +NT+ +R VS D TV +LL + Sbjct: 4979 AVLLAKVSASSDVAVGFPIAGRRDPA----LDDVVGFFVNTLVLRVDVSGDPTVAELLAR 5034 Query: 1391 LQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYPIDTS-AFMGVQELA 1442 ++ EH+ + LN ++ H + L P + S + V L Sbjct: 5035 VRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNIEPTELSLGQVRVIPLP 5094 Query: 1443 VTEFNNREYNHYPLSVMALPGHE---LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDD 1499 V R + L+ P +G VE+ T VFD + +E L R +R+L AM D Sbjct: 5095 VDTRTARMDLAWSLAERWTPDGSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLAAMTAD 5154 Query: 1500 PARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGE 1559 P RRLSS+D++D E +LD NRAVLT+P P SIPEVFA V R P A AVT Sbjct: 5155 PGRRLSSIDLLDPAEHARLDALGNRAVLTRPQHPPTSIPEVFAAHVARTPHAVAVTCGRR 5214 Query: 1560 SLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSV 1619 S Y ELD +AN+LA+LL +GA PG VAL++ RSA+A+ AIL VLK GAAYLPIDPS+ Sbjct: 5215 SWTYRELDSSANRLAHLLIHHGAGPGDCVALLLERSAEAVAAILGVLKAGAAYLPIDPSL 5274 Query: 1620 PAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAY 1679 P+AR+EFML DA P A +T+ + R +D V++VDDP++ P T P+PD+IAY Sbjct: 5275 PSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPVTAPPAPAPDNIAY 5334 Query: 1680 MIYTSGTTGVPKGVAITHGNVTQVLDTLPAE-LPAGPGAVWSQWHSLVFDVSVWEIWGAL 1738 +IYTSGTTGVPKGVA+TH N TQ+ +L A LPA PG VW Q HSL FD SVWEI+GAL Sbjct: 5335 LIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWEIFGAL 5394 Query: 1739 LHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACP 1798 L+GGR+++VP+ + SP DLHALLV+E V++L QTPS V ++SP+GLE T L VAGEACP Sbjct: 5395 LNGGRVLVVPDDVVRSPKDLHALLVAERVDMLTQTPSEVGVLSPDGLESTTLAVAGEACP 5454 Query: 1799 TEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPV 1858 EVVDRWA RVMIN YGPTE+TI AA+SAPL+PG + PIG+PVP A VLD LRPV Sbjct: 5455 VEVVDRWAPGRVMINVYGPTETTIVAAVSAPLTPGPEAPPIGAPVPGTALRVLDAHLRPV 5514 Query: 1859 PPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYL 1918 PPGVVGELY+A LT +RFVACPFG G RMYRTGDLVRWG DGQLQYL Sbjct: 5515 PPGVVGELYVAGAGVSTGYLGRPGLTASRFVACPFGGAGERMYRTGDLVRWGADGQLQYL 5574 Query: 1919 GRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAAR 1978 GRADEQVKIRGYRIELGEIQ+AL+ +DGVDQA VIAREDRPGDKRLVGY+TGTAD A R Sbjct: 5575 GRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYVTGTADLAQLR 5634 Query: 1979 SELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGI 2038 + L RLP YMVPAAV+ L+ LPLT +GKLD ALPAP+YQ + Y AP E+ LA + Sbjct: 5635 TALAERLPGYMVPAAVLMLDALPLTPSGKLDTGALPAPDYQGPEGYLAPAGAVEEILAWL 5694 Query: 2039 FAHVLGV-ERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHV 2097 +A VLG+ R AMR+ AA+ ALD L VR +FEAP+V LS + Sbjct: 5695 YAQVLGLPRRVGVQESFFDLGGDSLSAMRLVAAIYNALDIHLPVRAVFEAPSVRSLSQRL 5754 Query: 2098 EHD-AGERTDRVSFAAVHGSDVTEVHARDLTLDKFIXXXXXXXXXXXXXXXGAVQTVLLT 2156 D A + R FA+VHG D TEV+A DLTLDKFI V+TVLLT Sbjct: 5755 NADPAVAQGLRADFASVHGRDATEVYASDLTLDKFIDAATLSAAPALPGPGAEVRTVLLT 5814 Query: 2157 GATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDEDARRRLEATFDT-DPLLRKHFNELA 2215 GATGFLGRYL+L+WL +L D K+ICLVR SD+DARRRLE TFD+ DP L ++F+ELA Sbjct: 5815 GATGFLGRYLVLQWLERLELADGKLICLVRAASDDDARRRLERTFDSGDPALLRYFHELA 5874 Query: 2216 TERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDSAAFVNSVLPYSELFGPNVVGTAEL 2275 + L+V+AGDKG+ NLGLD++TWQRLA++VDLIVD+AA VN VLPY ELFGPNV GTAEL Sbjct: 5875 ADHLEVIAGDKGRANLGLDDRTWQRLADTVDLIVDAAAVVNGVLPYQELFGPNVAGTAEL 5934 Query: 2276 IRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGE 2335 IR AL+++LKP+++VST++VG QIEPS FTE ADIR+ R I+ GY NGYGNSKWAGE Sbjct: 5935 IRLALSTRLKPYSYVSTANVGDQIEPSAFTEDADIRVAGPIRTIDGGYGNGYGNSKWAGE 5994 Query: 2336 VLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATGVAPGSFYQRGD 2395 VLLREAHD CGLPV+VFR MI+ D +YAGQLN+ D +R++ S+VA+GVAP SFY+ Sbjct: 5995 VLLREAHDLCGLPVSVFRCDMILADTSYAGQLNLPDMFTRLLFSVVASGVAPRSFYRLDA 6054 Query: 2396 NGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDSTASGFETYHVMNPHDDGIGIDTYID 2455 +G RQRAHFD LPV+FVA+AI LG QV R +GF TYHVMNPHDDGIG+D Y+D Sbjct: 6055 HGNRQRAHFDALPVEFVAEAIATLGAQVGR----DAGTGFATYHVMNPHDDGIGLDEYVD 6110 Query: 2456 WLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQNSVLQMLTLLKQQAGELQPPVPTRG 2515 WLI+AGYPIER++DF +WL R E AL LS++QR SVLQ+L L + A + P P RG Sbjct: 6111 WLIDAGYPIERVDDFDQWLHRMETALHALSERQRHQSVLQLLAL--RNARHVPPADPARG 6168 Query: 2516 SFAPADRFQAAVRDANIGVEGEIPHVTREVIVKYVTDLQLLGLL 2559 P +RF+AAV++A IG + +IPH+T VIVKYVTDLQLLGLL Sbjct: 6169 CLGPTERFRAAVQEAKIGADNDIPHITAPVIVKYVTDLQLLGLL 6212 Score = 755 bits (1949), Expect = 0.0 Identities = 473/1043 (45%), Positives = 608/1043 (58%), Gaps = 58/1043 (5%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 VLPL+ Q L F VY + + + + G LD L A+ VVARH +L Sbjct: 1125 VLPLSFAQSRLWFIDQLHGP--SPVYNMAVALNLRGPLDTDALGAALGDVVARHESLRTL 1182 Query: 1152 FVEQFGEPVQVLTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 F G P QV+ + W+ +D P + + DL RA Sbjct: 1183 FPAPDGAPRQVVLEAERAEVDWQVVDAAR---WPASWLAEATHEAARYTFDLATEIPLRA 1239 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVN 1262 L R + ++H V HHI DGWSL L++++ A Y R P AP Y ++ Sbjct: 1240 WLFRRNHDEHVLVAVVHHIAADGWSLTPLVRDLGAAYASRCRGRPPDWAPLPVQYADYTL 1299 Query: 1263 WLXXXXXXXXXXX---------WREVLDGFETPTLVA-PPGVPGPRGIESYRVS------ 1306 W W+ L G P VA P P P + S Sbjct: 1300 WQRAQFGDLDDPDSPIATQLQYWQRALAGM--PERVALPTDRPYPLVADHLGASVQVHWP 1357 Query: 1307 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESM 1364 AE + + +LAR+ + T V+QAA LL ++ DVA G ++GR PA + + Sbjct: 1358 AELQQHIAQLARTHNATSFMVVQAALAVLLSTLSANPDVAVGFPIAGRRDPA----LDDV 1413 Query: 1365 VGLLINTVPIRAKVSADTTVGDLL-----RQLQSHHNDTLEHEHLA--LNDIHHVSGHEQ 1417 VG +NT+ +R ++ D ++ +LL R LQ++ N + E L LN ++ H Sbjct: 1414 VGFFVNTLVLRVDLADDPSIAELLGQVRHRSLQAYENQDVPFELLVERLNPTRSLAHHPL 1473 Query: 1418 LFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMA----LPGHELGL--RVE 1471 + L + P+D S +G + N+ + +A G G+ VE Sbjct: 1474 VQVMLAWQNNDPVDVS--LGDVHVTPMPLENQVARMDLVWSLAERWTADGRPDGIDGTVE 1531 Query: 1472 YDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPV 1531 + T VFD + IETL+ R QR+L AM DPAR +SS+D++D+ E LD NRA LT+P Sbjct: 1532 FRTDVFDAASIETLVRRLQRVLLAMTADPARPVSSIDILDEPEYAHLDALGNRAALTRPA 1591 Query: 1532 DSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALM 1591 SI ++FA QV R PEA A++ S Y ELD +AN+LA +LA GA PG+ VA++ Sbjct: 1592 TGWVSISQLFAAQVARTPEAVAISCGERSWTYRELDSSANRLARVLAGRGARPGERVAVL 1651 Query: 1592 VPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDL 1651 VPRSA A+V+ILAVLKTGAAY+PIDP +P+AR++FML DA PV VTT +LR+ D Sbjct: 1652 VPRSAGAVVSILAVLKTGAAYVPIDPGLPSARIDFMLADAVPVVTVTTAELRASAGDPD- 1710 Query: 1652 QVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAEL 1711 +VV +DDPA + P+PDDIAY+IYTSGTTGVPKGVA+TH NVTQ+L +L L Sbjct: 1711 RVVAIDDPAPHVPRIGGRAAPAPDDIAYVIYTSGTTGVPKGVAVTHHNVTQLLGSLDDRL 1770 Query: 1712 PAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLY 1771 G G VWSQ HSL FD SVWEI+GALL GGRLVIVP+ + SP+DLHALL+ EGV VL Sbjct: 1771 --GLGRVWSQCHSLAFDFSVWEIFGALLRGGRLVIVPDDVVRSPEDLHALLIGEGVTVLS 1828 Query: 1772 QTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLS 1831 QTPSA +SPE LE ALV+ GEACP E++DRWA R+M+N YGPTE+T+YA ++ PL Sbjct: 1829 QTPSAAAALSPERLESVALVLGGEACPVELMDRWAPGRLMVNQYGPTETTLYATMTTPLR 1888 Query: 1832 PGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVAC 1891 G VPIGSPVP A FVLD LR VPPGVVGELY+A LT +RFVAC Sbjct: 1889 AGGAAVPIGSPVPGAALFVLDGRLRRVPPGVVGELYVAGRGVAAGYLGRAALTASRFVAC 1948 Query: 1892 PFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAV 1951 PFG G RMYRTGDL RWG DGQL Y+GRADEQVKIRG+RIELGEI++ L+ +DGV+QA Sbjct: 1949 PFGGTGTRMYRTGDLARWGADGQLHYVGRADEQVKIRGFRIELGEIRSVLAGLDGVEQAA 2008 Query: 1952 VIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRR 2011 VIAR+D G RLV YITGTADPA R++L +RLP YMVP+AVV L+ LPLT NGKLD R Sbjct: 2009 VIARDDGAGHPRLVAYITGTADPAELRAQLADRLPGYMVPSAVVVLDALPLTGNGKLDTR 2068 Query: 2012 ALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAV 2071 ALPAP+Y + RYRAP E+ LAGI+A VLGVER +M+V A Sbjct: 2069 ALPAPDY-AGGRYRAPGDAIEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVARA 2127 Query: 2072 NTALDADLSVRTLFEAPTVAKLS 2094 A + R +F TVA+L+ Sbjct: 2128 RAA-GVMCTARDVFVEQTVARLA 2149 Score = 751 bits (1940), Expect = 0.0 Identities = 472/1098 (42%), Positives = 618/1098 (56%), Gaps = 66/1098 (6%) Query: 1045 RLWFEA--LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGL 1102 R FEA +A + VRGGG L AR+ + V+PL+ Q L Sbjct: 41 RTLFEAPTVAQLAPRVRGGGRTL-------ARVVAGERPA---------VVPLSFAQSRL 84 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 F +Y + + + G LD LR A+ V+ARH +L F G P QV Sbjct: 85 WFLDQLQGP--SPMYNMAAALKLQGPLDVSVLRAALADVIARHESLRTVFAVSDGTPHQV 142 Query: 1163 LTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHR 1220 + I W +D G +P E + AA A DL RA L R S ++H Sbjct: 143 VIPAEQADIGWDVVDTAG--WSPARMKEAIDAAAGHAF-DLSTEIPLRATLFRNSLDEHV 199 Query: 1221 FVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNWLXXXXXXXXX 1273 V HHI DG SL LL+++ A Y R+P P Y ++ W Sbjct: 200 LVAVAHHIAADGSSLNPLLRDLTAAYTARCAGRVPDWVPLPVQYIDYALWQRAQFGDLED 259 Query: 1274 XX---------WREVLDGFET----PTLVAPPGVPGPRGIE-SYRVSAETTRALGELARS 1319 W+E L G PT P V RG A + + LAR Sbjct: 260 PDSPIAGQLRYWQEALAGLPERLALPTDRPYPAVADHRGARVDIDWPASLQQQVSALARV 319 Query: 1320 QHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVS 1379 + T V+QA LL ++ DVA G ++GR D A + +VG +NT+ +R +S Sbjct: 320 HNATSFMVVQAGLAVLLAKLGASCDVAVGFPIAGR-GDPA-LDDLVGFFVNTLVLRVDLS 377 Query: 1380 ADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYPIDT 1432 D TVG++L +++ EH+ + LN ++ H + L P T Sbjct: 378 GDPTVGEILARVRQRSLAAYEHQDVPFEILVERLNPTRSLAHHPLIQVMLTWRGDDP--T 435 Query: 1433 SAFMGVQELAVTEFN----NREYNHYPLSVMALPGHELGLR--VEYDTSVFDVSEIETLI 1486 +G E+A + + G G+ VE+ T VFD I TL Sbjct: 436 RLRLGELEVAALPIDIGTARMDLTFSLCERWTEEGRPAGIAGTVEFRTDVFDADTIRTLT 495 Query: 1487 DRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVE 1546 +R +R+L+ + DP R LSS++V++D E +LD + NRA L + S+P +F + Sbjct: 496 ERLRRVLDVLTADPGRHLSSIEVLEDTEFARLDIFGNRAALGRSTTGA-SVPALFGAWAQ 554 Query: 1547 RDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVL 1606 R P A A++ Y E+DE AN+LA+LL +G G+ V L++ RSA+A+VAIL VL Sbjct: 555 RVPGAVAISSADRCWTYREVDETANRLAHLLIQHGVDRGQYVGLLLDRSAEAVVAILGVL 614 Query: 1607 KTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPS 1666 K GAAY+P+DP+VPAAR+ F++ DA VT RSR G +V++DDPA+ YP+ Sbjct: 615 KAGAAYVPMDPAVPAARIAFIVADADLRVVVTDAGSRSRLTGLGAAIVDLDDPALADYPA 674 Query: 1667 TTLLTPSP--DDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHS 1724 T P P DIA++IYTSGTTG PKGVA++H N+TQ+ +L + GP VWSQ HS Sbjct: 675 TEPAGPGPAAGDIAHVIYTSGTTGEPKGVAVSHRNITQLFASLDTGITLGPDQVWSQCHS 734 Query: 1725 LVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEG 1784 L FD SVWEIW ALLHGGRLV+V +++A SPDDL LL+ E V VL QTPSA +SP+G Sbjct: 735 LAFDFSVWEIWAALLHGGRLVVVSDAVARSPDDLRRLLIRERVTVLTQTPSAAGALSPQG 794 Query: 1785 LEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVP 1844 L+ ALV+ E CP E+VDRWA DRVMIN YGPTE+T++ + S PL+ GS PIGSPV Sbjct: 795 LDSVALVIGAEPCPPELVDRWAPDRVMINVYGPTETTMWVSHSRPLAAGSGAPPIGSPVA 854 Query: 1845 KGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTG 1904 + FVLD WL P P GV GELY+A LT +RFVACPFG G RMYRTG Sbjct: 855 GASFFVLDPWLCPAPVGVTGELYVAGAGVGAGYVGRAALTASRFVACPFGGTGTRMYRTG 914 Query: 1905 DLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRL 1964 DLVRWG DGQL Y+GRADEQVKIRGYRIELGEI++AL+D+DGV+QA VIARED PG KRL Sbjct: 915 DLVRWGADGQLHYVGRADEQVKIRGYRIELGEIRSALTDLDGVEQAAVIAREDSPGHKRL 974 Query: 1965 VGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRY 2024 V Y+TGTADPA R++L +RLP YM+P+AV+ L+ LPLTVNGKLD RALPAPE ++ RY Sbjct: 975 VAYLTGTADPAQVRTQLADRLPGYMLPSAVLALDALPLTVNGKLDTRALPAPELRAENRY 1034 Query: 2025 RAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTL 2084 RAP+ TE++LA ++A +LG+ER AMR+ AVN LDADL+VR L Sbjct: 1035 RAPQNPTEESLADVYARLLGLERVGVDDSFFELGGDSLSAMRLITAVNAELDADLTVRAL 1094 Query: 2085 FEAPTVAKLSLHVEHDAG 2102 FEAPTVA+L+ V G Sbjct: 1095 FEAPTVAQLAPRVAAGTG 1112 Score = 737 bits (1903), Expect = 0.0 Identities = 454/961 (47%), Positives = 570/961 (59%), Gaps = 55/961 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P R L S DLLD EH +++ WGNR L+ P P ++P LF QV AP AVAL Sbjct: 3044 MPADPD-RPLRSLDLLDSTEHTRLQRWGNRPALSRPATGP-SLPELFTAQVANAPHAVAL 3101 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS TYRELDEAS RLAH+LA HGA PG VA L RS EAI+++L+VLKTGAAYLP Sbjct: 3102 RCAGRSMTYRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYLP 3161 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P RI FM+ DA PV A++TA LR+RL+ + L V+D+A A +P L P P Sbjct: 3162 IDPALPATRIEFMLGDAAPVVAVSTAGLRARLEAFGLPVVDVA--ATGAQPGGPLPPPAP 3219 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D++AY+ YTSGTTGVPK VAVTH NV QL+ +LHA LP G G VWSQ HS FDVSV EI Sbjct: 3220 DNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLP-GTG-VWSQCHSYGFDVSVQEI 3277 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGAL GGRLVVVPESV SSPD+LH LLI E V+VL QTPSA LSP L + L++ G Sbjct: 3278 WGALAGGGRLVVVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLHAA-LVIGG 3336 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 E CP L DRWAPGRVMINAYGPTE T+ A +S PL LFVLD W Sbjct: 3337 EPCPAALADRWAPGRVMINAYGPTETTVDAVLSTPLAAGAGAPPLGSPVAGATLFVLDGW 3396 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GV GELY+AG GVA GY+GR LTA+RFVACPFG G RMYRTGDLVRW DG+ Sbjct: 3397 LRPVPAGVTGELYIAGAGVAAGYLGRAGLTAARFVACPFGGAGARMYRTGDLVRWDRDGR 3456 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L Y+ RAD+QVKIRG+RIELGEI +ALA+LDGV+QA VIAREDRPG+KR+VGY+TGTADP Sbjct: 3457 LHYVARADQQVKIRGHRIELGEIHSALAELDGVEQAAVIAREDRPGEKRIVGYLTGTADP 3516 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A +R LAE LPAYMVP AV+ ++ +PLT NGKLD RALPAPEY A YRAPSTP E+ Sbjct: 3517 AAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEYAGGA--YRAPSTPTEE 3574 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCR--PRDIFVEQTXXX 598 I+A +Y QVLG+ RVGVDDSFFDLGGDS+ +M+V+A A G+ R R +F T Sbjct: 3575 IIAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNA-GLDARLSVRVLFEAPTIAQ 3633 Query: 599 XXXXXXXXXESHVVDEGVGPVVATPI------MRWLREVDGPTGQFNQTVITQAPAGVTE 652 P+ + ++ ++ GP+ +N + V Sbjct: 3634 LAARLGEGGHRFAAVVAAERPAVVPLSFAQSRLWFIGQLHGPSPVYNMVAALRLHGPVDI 3693 Query: 653 DDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGAR--ECLRTVDALTDDVL 710 + L ++ RH +LR T + T +L P+ +G + + A DDV+ Sbjct: 3694 GALGAALHDVVTRHESLRTVFAAT-DGTPAQVVLPPDRADIGWQVIDASGWSPARVDDVI 3752 Query: 711 VE-ARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCT 766 + AR+ D AA + AV +R E LV ++HH+A DG S L+ DL A+A Sbjct: 3753 RDTARHTFDLAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGWSLTPLVRDLARAYASRSA 3812 Query: 767 GQS---IELPAGGTSFARWSALLAEHAKTDTVRDLADA----WR-AVTSVPQALPPVQPD 818 G+ + LP + W A+ D L W A+ +P+ L + D Sbjct: 3813 GRVPDWVPLPVQYVDYTLWQR--AQFGDLDDPHSLIAGQLRYWESALAGMPERL-ELPTD 3869 Query: 819 TDTYVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPI 875 V A AS+ VE QL + + A A ++ A + + SD + Sbjct: 3870 RPYPVVADFRGASVAVEWPAQLQQQISRLAGAHNATSFMVVQAALAVLLAKVSASSDVAV 3929 Query: 876 GVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKE 935 G + GR D DV VG+F V L V+GD + ++ V++ Sbjct: 3930 GFPIA--GRRDPALDDV-----VGFF---------VNTLVLRVDVSGDPTVAELLARVRQ 3973 Query: 936 Q 936 + Sbjct: 3974 R 3974 Score = 732 bits (1889), Expect = 0.0 Identities = 448/1044 (42%), Positives = 584/1044 (55%), Gaps = 57/1044 (5%) Query: 1116 VYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPM--IAWRY 1173 VY + + + G +D L A+H VV RH +L F G P QV+ I W+ Sbjct: 3678 VYNMVAALRLHGPVDIGALGAALHDVVTRHESLRTVFAATDGTPAQVVLPPDRADIGWQV 3737 Query: 1174 LDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGW 1233 +D G ++ + DL RA L+R +H V HHI DGW Sbjct: 3738 IDASG---WSPARVDDVIRDTARHTFDLAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGW 3794 Query: 1234 SLPILLQEIFAGYFGHR-------LPAAAPYRNFVNWLXXXXXXXXXXX---------WR 1277 SL L++++ Y +P Y ++ W W Sbjct: 3795 SLTPLVRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLRYWE 3854 Query: 1278 EVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHTTINTVLQAAW 1332 L G E PT P V RG + A+ + + LA + + T V+QAA Sbjct: 3855 SALAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGAHNATSFMVVQAAL 3914 Query: 1333 TQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQ 1390 LL +++ DVA G ++GR PA + +VG +NT+ +R VS D TV +LL + Sbjct: 3915 AVLLAKVSASSDVAVGFPIAGRRDPA----LDDVVGFFVNTLVLRVDVSGDPTVAELLAR 3970 Query: 1391 LQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYPIDTS-AFMGVQELA 1442 ++ EH+ + LN ++ H + L P + S + V L Sbjct: 3971 VRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNIEPTELSLGQVRVIPLP 4030 Query: 1443 VTEFNNREYNHYPLSVMALPGHE---LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDD 1499 V R + L+ P +G VE+ T VFD + +E L R +R+L AM D Sbjct: 4031 VDTRTARMDLAWSLAERWTPDGSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLAAMTAD 4090 Query: 1500 PARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGE 1559 P RRLSS+D++D DE +LD NRA LT+P P SIP +FA QV R P A A+T G Sbjct: 4091 PGRRLSSIDLLDPDEHARLDALGNRAALTRPQHPPTSIPAMFAAQVARTPHAVALTANGR 4150 Query: 1560 SLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSV 1619 S+ Y L+E ANQLA+ L YGA PG+ VA+++ RSA+A+ AIL VLK GAAYLPIDPS+ Sbjct: 4151 SVTYRRLEEHANQLAHQLIRYGAGPGRCVAVLLERSAEAVAAILGVLKAGAAYLPIDPSL 4210 Query: 1620 PAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAY 1679 P+AR+EFML DA P A +T+ + R +D V++VDDP++ P T P+PD+IAY Sbjct: 4211 PSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPVTAPPAPAPDNIAY 4270 Query: 1680 MIYTSGTTGVPKGVAITHGNVTQVLDTLPAE-LPAGPGAVWSQWHSLVFDVSVWEIWGAL 1738 +IYTSGTTGVPKGVA+TH N TQ+ +L A LPA PG VW Q HSL FD SVWEI+GAL Sbjct: 4271 LIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWEIFGAL 4330 Query: 1739 LHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAV----RMMSPEGLEGTALVVAG 1794 L+GGR+++VP+ + SP+DL ALL+ E V+VL QTPSA R S L ++ G Sbjct: 4331 LNGGRVLVVPDDVVRSPEDLCALLIDEHVDVLSQTPSAFDALQRADSARRLNPQTVIFGG 4390 Query: 1795 EACPTEVVDRWAVDRV----MINAYGPTESTIYAAISAPLSPGSD--VVPIGSPVPKGAT 1848 EA + W +IN YG TE+T++A+ + D V PIG P+ Sbjct: 4391 EALIPHRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDIDGNVSPIGMPLAHLGF 4450 Query: 1849 FVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVR 1908 FVLD WLRPVP GV GELY+A LT +RFVACPFG G RMYRTGDL R Sbjct: 4451 FVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACPFGGAGERMYRTGDLAR 4510 Query: 1909 WGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYI 1968 WG DGQL YLGRAD+QVKIRGYRIELGEIQ+AL+++DGV+QA VIAREDRPGDKRLVGY+ Sbjct: 4511 WGTDGQLHYLGRADQQVKIRGYRIELGEIQSALAELDGVEQATVIAREDRPGDKRLVGYV 4570 Query: 1969 TGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPE 2028 TGTADPA R+ L RLPAY+VPAAVV ++ +PLT NGKLD ALPAP+Y A +Y AP Sbjct: 4571 TGTADPAQLRTALAERLPAYLVPAAVVAIDAMPLTPNGKLDTGALPAPDYHGADQYHAPA 4630 Query: 2029 TETEKTLAGIFAHVLGV---ERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLF 2085 + E+TLA I+AHVL V AMR+ A VN+ LD L VR LF Sbjct: 4631 SAVEQTLADIYAHVLDVRPPRLVGIDDSFFDLGGDSLSAMRLVAEVNSRLDVHLGVRALF 4690 Query: 2086 EAPTVAKLSLHVEHDAGERTDRVS 2109 EAPT+ +L+ + D R V+ Sbjct: 4691 EAPTIRRLAARLGADGSARAPLVA 4714 Score = 732 bits (1889), Expect = 0.0 Identities = 378/578 (65%), Positives = 441/578 (76%), Gaps = 4/578 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P R L S DLLD EH +++ GNRAVLT P P +IP +FA V R P AVA+ Sbjct: 5151 MTADPGRR-LSSIDLLDPAEHARLDALGNRAVLTRPQHPPTSIPEVFAAHVARTPHAVAV 5209 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G RSWTYRELD ++NRLAH+L HGA PG VA L+ RS EA+ +IL VLK GAAYLP Sbjct: 5210 TCGRRSWTYRELDSSANRLAHLLIHHGAGPGDCVALLLERSAEAVAAILGVLKAGAAYLP 5269 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP+ P ARI FM++DA P A LT+ + RL +YD VID+ DP+I +P A P P Sbjct: 5270 IDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPVTAPPAPAP 5329 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHA-DLPSGPGQVWSQWHSLVFDVSVWE 239 D++AY+ YTSGTTGVPK VAVTH N TQL ++L A LP+ PG+VW Q HSL FD SVWE Sbjct: 5330 DNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWE 5389 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVA 299 I+GALL+GGR++VVP+ V SP DLH LL+ E+V +L QTPS G+LSP+GLESTTL VA Sbjct: 5390 IFGALLNGGRVLVVPDDVVRSPKDLHALLVAERVDMLTQTPSEVGVLSPDGLESTTLAVA 5449 Query: 300 GEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 GEACP E+VDRWAPGRVMIN YGPTE TI AA+S PL L VLD Sbjct: 5450 GEACPVEVVDRWAPGRVMINVYGPTETTIVAAVSAPLTPGPEAPPIGAPVPGTALRVLDA 5509 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 LRP P GVVGELYVAG GV+TGY+GRP LTASRFVACPFG GERMYRTGDLVRWG+DG Sbjct: 5510 HLRPVPPGVVGELYVAGAGVSTGYLGRPGLTASRFVACPFGGAGERMYRTGDLVRWGADG 5569 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+YLGRADEQVKIRGYRIELGEIQ+ALA LDGVDQA VIAREDRPGDKRLVGY+TGTAD Sbjct: 5570 QLQYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGDKRLVGYVTGTAD 5629 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 AQLRTALAE LP YMVP AV++LD +PLT +GKLD ALPAP+Y+ Y AP+ E Sbjct: 5630 LAQLRTALAERLPGYMVPAAVLMLDALPLTPSGKLDTGALPAPDYQ-GPEGYLAPAGAVE 5688 Query: 540 QILADVYAQVLGV-ERVGVDDSFFDLGGDSILSMQVVA 576 +ILA +YAQVLG+ RVGV +SFFDLGGDS+ +M++VA Sbjct: 5689 EILAWLYAQVLGLPRRVGVQESFFDLGGDSLSAMRLVA 5726 Score = 705 bits (1820), Expect = 0.0 Identities = 427/937 (45%), Positives = 550/937 (58%), Gaps = 60/937 (6%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+P R L S ++L++ E +++++GNRA L T ++PALF R P AVA+ Sbjct: 505 LTADPG-RHLSSIEVLEDTEFARLDIFGNRAAL-GRSTTGASVPALFGAWAQRVPGAVAI 562 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 S DR WTYRE+DE +NRLAH+L +HG G V L+ RS EA+++IL VLK GAAY+P Sbjct: 563 SSADRCWTYREVDETANRLAHLLIQHGVDRGQYVGLLLDRSAEAVVAILGVLKAGAAYVP 622 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P ARI F+++DA +T A RSRL A++D+ DPA+ P+ +GP P Sbjct: 623 MDPAVPAARIAFIVADADLRVVVTDAGSRSRLTGLGAAIVDLDDPALADYPATEPAGPGP 682 Query: 181 --DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVW 238 D+A++ YTSGTTG PK VAV+H N+TQL ++L + GP QVWSQ HSL FD SVW Sbjct: 683 AAGDIAHVIYTSGTTGEPKGVAVSHRNITQLFASLDTGITLGPDQVWSQCHSLAFDFSVW 742 Query: 239 EIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIV 298 EIW ALLHGGRLVVV ++V SPDDL LLI E+V+VL QTPSAAG LSP+GL+S L++ Sbjct: 743 EIWAALLHGGRLVVVSDAVARSPDDLRRLLIRERVTVLTQTPSAAGALSPQGLDSVALVI 802 Query: 299 AGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLD 358 E CP ELVDRWAP RVMIN YGPTE T++ + S PL FVLD Sbjct: 803 GAEPCPPELVDRWAPDRVMINVYGPTETTMWVSHSRPLAAGSGAPPIGSPVAGASFFVLD 862 Query: 359 KWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSD 418 WL PAP GV GELYVAG GV GY+GR LTASRFVACPFG TG RMYRTGDLVRWG+D Sbjct: 863 PWLCPAPVGVTGELYVAGAGVGAGYVGRAALTASRFVACPFGGTGTRMYRTGDLVRWGAD 922 Query: 419 GQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA 478 GQL Y+GRADEQVKIRGYRIELGEI++AL LDGV+QA VIARED PG KRLV Y+TGTA Sbjct: 923 GQLHYVGRADEQVKIRGYRIELGEIRSALTDLDGVEQAAVIAREDSPGHKRLVAYLTGTA 982 Query: 479 DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPA 538 DPAQ+RT LA+ LP YM+P+AV+ LD +PLTVNGKLD RALPAPE R A N YRAP P Sbjct: 983 DPAQVRTQLADRLPGYMLPSAVLALDALPLTVNGKLDTRALPAPELR-AENRYRAPQNPT 1041 Query: 539 EQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXX 598 E+ LADVYA++LG+ERVGVDDSFF+LGGDS+ +M+++ A ++ + T Sbjct: 1042 EESLADVYARLLGLERVGVDDSFFELGGDSLSAMRLITAVNA--------ELDADLTVRA 1093 Query: 599 XXXXXXXXXESHVVDEGVG----------PVV-----ATPIMRWLREVDGPTGQFNQTVI 643 + V G G P V A + ++ ++ GP+ +N V Sbjct: 1094 LFEAPTVAQLAPRVAAGTGRAGRLVAAERPAVLPLSFAQSRLWFIDQLHGPSPVYNMAVA 1153 Query: 644 TQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVD 703 + D + L ++ RH +LR + + +L E V + VD Sbjct: 1154 LNLRGPLDTDALGAALGDVVARHESLR-TLFPAPDGAPRQVVLEAERAEVD----WQVVD 1208 Query: 704 A-------LTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRIL 753 A L + AR D A + A R LV ++HH+A DG S L Sbjct: 1209 AARWPASWLAEATHEAARYTFDLATEIPLRAWLFRRNHDEHVLVAVVHHIAADGWSLTPL 1268 Query: 754 LEDLNIAWAQHCTGQSIE---LPAGGTSFARWS-ALLAEHAKTDT-VRDLADAW-RAVTS 807 + DL A+A C G+ + LP + W A + D+ + W RA+ Sbjct: 1269 VRDLGAAYASRCRGRPPDWAPLPVQYADYTLWQRAQFGDLDDPDSPIATQLQYWQRALAG 1328 Query: 808 VPQ--ALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRA-GVQDILLVAFGLAW 864 +P+ ALP +P + A L AS+ V +L + R ++V LA Sbjct: 1329 MPERVALPTDRPYP---LVADHLGASVQVHWPAELQQHIAQLARTHNATSFMVVQAALAV 1385 Query: 865 TEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 ++ + V GR D DV VG+F Sbjct: 1386 LLSTLSANPDVAVGFPIAGRRDPALDDV-----VGFF 1417 Score = 689 bits (1779), Expect = 0.0 Identities = 437/974 (44%), Positives = 559/974 (57%), Gaps = 60/974 (6%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P R L S DLLD DEH +++ GNRA LT P P +IPA+FA QV R P AVAL Sbjct: 4087 MTADPGRR-LSSIDLLDPDEHARLDALGNRAALTRPQHPPTSIPAMFAAQVARTPHAVAL 4145 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 + RS TYR L+E +N+LAH L +GA PG VA L+ RS EA+ +IL VLK GAAYLP Sbjct: 4146 TANGRSVTYRRLEEHANQLAHQLIRYGAGPGRCVAVLLERSAEAVAAILGVLKAGAAYLP 4205 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP+ P ARI FM++DA P A LT+ + RL +YD VID+ DP+I +P A P P Sbjct: 4206 IDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPVTAPPAPAP 4265 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHA-DLPSGPGQVWSQWHSLVFDVSVWE 239 D++AY+ YTSGTTGVPK VAVTH N TQL ++L A LP+ PG+VW Q HSL FD SVWE Sbjct: 4266 DNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWE 4325 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGML----SPEGLESTT 295 I+GALL+GGR++VVP+ V SP+DL LLI E V VL QTPSA L S L T Sbjct: 4326 IFGALLNGGRVLVVPDDVVRSPEDLCALLIDEHVDVLSQTPSAFDALQRADSARRLNPQT 4385 Query: 296 LIVAGEACPTELVDRWAPGRV----MINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXX 351 +I GEA + W G +IN YG TE T++A+ E + Sbjct: 4386 VIFGGEALIPHRLGGWLDGHPARPRLINMYGITETTVHASFREIVDGDIDGNVSPIGMPL 4445 Query: 352 XXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRT 409 L FVLD WLRP P GV GELY+AG GVA GY+GRP LTASRFVACPFG GERMYRT Sbjct: 4446 AHLGFFVLDGWLRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACPFGGAGERMYRT 4505 Query: 410 GDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKR 469 GDL RWG+DGQL YLGRAD+QVKIRGYRIELGEIQ+ALA+LDGV+QA VIAREDRPGDKR Sbjct: 4506 GDLARWGTDGQLHYLGRADQQVKIRGYRIELGEIQSALAELDGVEQATVIAREDRPGDKR 4565 Query: 470 LVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAAN 529 LVGY+TGTADPAQLRTALAE LPAY+VP AVV +D +PLT NGKLD ALPAP+Y A+ Sbjct: 4566 LVGYVTGTADPAQLRTALAERLPAYLVPAAVVAIDAMPLTPNGKLDTGALPAPDYH-GAD 4624 Query: 530 DYRAPSTPAEQILADVYAQVLGV---ERVGVDDSFFDLGGDSILSMQVVARARA-AGIQC 585 Y AP++ EQ LAD+YA VL V VG+DDSFFDLGGDS+ +M++VA + + Sbjct: 4625 QYHAPASAVEQTLADIYAHVLDVRPPRLVGIDDSFFDLGGDSLSAMRLVAEVNSRLDVHL 4684 Query: 586 RPRDIFVEQTXXXXXXXXXXXXESHVVDEGVGPVVATPI------MRWLREVDGPTGQFN 639 R +F T + P+ + ++ ++ GP+ N Sbjct: 4685 GVRALFEAPTIRRLAARLGADGSARAPLVAAERPAVVPLSFAQSRLWFIGQLHGPSPVHN 4744 Query: 640 QTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGAR--E 697 + Q + L ++ RH +LR + + + V EA +G + + Sbjct: 4745 MAIALQLHGRLDAAAFGAALADVVGRHESLRTLFPAHEGIPQQLVIEVDEAD-IGWQVID 4803 Query: 698 CLRTVDALTDDVLVE-ARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWRIL 753 A DDV+ + AR+ D AA + AV +R E LV ++HH+A DG S L Sbjct: 4804 ASGWSPARLDDVIRDTARHTFDLAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGWSLTPL 4863 Query: 754 LEDLNIAWAQHCTGQS---IELPAGGTSFARWSALLAEHAKTDTVRDLADA----WR-AV 805 + DL A+A G+ + LP + W A+ D L W A+ Sbjct: 4864 VRDLARAYASRSAGRVPDWVPLPVQYVDYTLWQR--AQFGDLDDPHSLIAGQLRYWESAL 4921 Query: 806 TSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVAFGL 862 +P+ L + D V A AS+ VE QL + + A A ++ A + Sbjct: 4922 AGMPERL-ELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGAHNATSFMVVQAALAV 4980 Query: 863 AWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAG 922 + SD +G + GR D DV VG+F V L V+G Sbjct: 4981 LLAKVSASSDVAVGFPIA--GRRDPALDDV-----VGFF---------VNTLVLRVDVSG 5024 Query: 923 DAALGGIVKAVKEQ 936 D + ++ V+++ Sbjct: 5025 DPTVAELLARVRQR 5038 Score = 73.2 bits (178), Expect = 5e-10 Identities = 103/414 (24%), Positives = 163/414 (39%), Gaps = 48/414 (11%) Query: 549 VLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXXXXXXXXXX 607 +LGV RVGV+DSFFDLGGDS+ +M+++A G R +F T Sbjct: 1 MLGVGRVGVEDSFFDLGGDSLSAMRLIAAVNGVLGAGVSVRTLFEAPTVAQLAPRVRGGG 60 Query: 608 ESHV-VDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQA 661 + V G P V A + +L ++ GP+ +N + + DV V+ A Sbjct: 61 RTLARVVAGERPAVVPLSFAQSRLWFLDQLQGPSPMYNMAAALKLQGPL---DVSVLRAA 117 Query: 662 LLD---RHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVD----ALTDDVLVEAR 714 L D RH +LR V + T ++ E +G + + T + + + A Sbjct: 118 LADVIARHESLR-TVFAVSDGTPHQVVIPAEQADIG-WDVVDTAGWSPARMKEAIDAAAG 175 Query: 715 NRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQS-- 769 + D + + A R + LV + HH+A DG S LL DL A+ C G+ Sbjct: 176 HAFDLSTEIPLRATLFRNSLDEHVLVAVAHHIAADGSSLNPLLRDLTAAYTARCAGRVPD 235 Query: 770 -IELPAGGTSFARWSALL---AEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTA 825 + LP +A W E + L A+ +P+ L + D A Sbjct: 236 WVPLPVQYIDYALWQRAQFGDLEDPDSPIAGQLRYWQEALAGLPERL-ALPTDRPYPAVA 294 Query: 826 GQLSASLDVETTRQLLGEVPAAFRA-GVQDILLVAFGLA--WTEFLNRSDTPIGVDVEGH 882 A +D++ L +V A R ++V GLA + D +G + G Sbjct: 295 DHRGARVDIDWPASLQQQVSALARVHNATSFMVVQAGLAVLLAKLGASCDVAVGFPIAGR 354 Query: 883 GRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQ 936 G D L VG+F V L ++GD +G I+ V+++ Sbjct: 355 G-------DPALDDLVGFF---------VNTLVLRVDLSGDPTVGEILARVRQR 392 Score = 44.7 bits (104), Expect = 0.20 Identities = 30/64 (46%), Positives = 35/64 (54%), Gaps = 2/64 (3%) Query: 2042 VLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDA 2101 +LGV R AMR+ AAVN L A +SVRTLFEAPTVA+L+ V Sbjct: 1 MLGVGRVGVEDSFFDLGGDSLSAMRLIAAVNGVLGAGVSVRTLFEAPTVAQLAPRVR--G 58 Query: 2102 GERT 2105 G RT Sbjct: 59 GGRT 62 >tr|A0QPH5|A0QPH5_MYCS2 Tax_Id=246196 SubName: Full=Peptide synthetase;[Mycobacterium smegmatis] Length = 2429 Score = 2520 bits (6531), Expect = 0.0 Identities = 1281/1983 (64%), Positives = 1509/1983 (76%), Gaps = 33/1983 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P+ L + LL E E D++ GN + L++ P V+IP FA +V APDA AL Sbjct: 420 MAADPAM-PLAAVRLLAESESDRLATIGNHSALSESAPDAVSIPERFAARVAEAPDAAAL 478 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 R+ TYRELDEA+NR AH L G PG+ VA + PR+ ++++IL K GAAY+P Sbjct: 479 TFEGRTLTYRELDEAANRFAHALLARGIGPGSRVALMSPRTDRSVIAILGAFKAGAAYVP 538 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDPA P AR+ F++ DA PVA +TTA+LRSR D +DLAVID+ DPAI P+ A+S PRP Sbjct: 539 VDPAVPAARVRFILDDASPVAVVTTAELRSRFDGHDLAVIDIDDPAIASLPATAVSDPRP 598 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH N+T L++ L LP PG VW HSL FD SVWEI Sbjct: 599 DDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVLEERLPK-PG-VWPLCHSLAFDASVWEI 656 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 ALL GGRLVVVPE+V SP+D H+LL+ E+V+ L QTPSA MLSP+GLES TL V G Sbjct: 657 SNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQVTFLTQTPSAVAMLSPDGLESMTLAVVG 716 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP LVDRWA R MINAYGPTE TI S PL LFVLD W Sbjct: 717 EACPPALVDRWATNRTMINAYGPTETTICVTSSSPLEPGSVVVPIGSALPRTALFVLDPW 776 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GV GELYVAG GV GYIGR LTASRFV CPFGE G RMYRTGDLVRWG DGQ Sbjct: 777 LRPVPTGVAGELYVAGDGVTCGYIGRSGLTASRFVPCPFGEPGARMYRTGDLVRWGRDGQ 836 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 LEYLGRADEQVKIRGYRIELGE+Q+ALA LDGV+ A I REDRPGD+RLVGYITGTADP Sbjct: 837 LEYLGRADEQVKIRGYRIELGEVQSALAALDGVESAAAIMREDRPGDRRLVGYITGTADP 896 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 +R LA+ LP YMVPTA+VVL +PLT + KLD RALPAPEY +A +YRAPS P E+ Sbjct: 897 VDIRAELADRLPPYMVPTAIVVLPALPLTSSNKLDTRALPAPEYANAEKNYRAPSNPVEE 956 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXX 600 +LAD+YAQVLGVER+GVDDSFFDLGGDSILSMQVVARARAAGIQCRPRD+FVEQT Sbjct: 957 VLADIYAQVLGVERIGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDVFVEQTVARLA 1016 Query: 601 XXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ 660 E VVD+G G TPI+ WLRE G T +FNQT++ QAP GVTE DVV +LQ Sbjct: 1017 SVATVATEIGVVDDGTGSAAPTPIIHWLREAGGATDEFNQTLVVQAPTGVTEPDVVAVLQ 1076 Query: 661 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA 720 ALLDRHATLRLRV+D+ EWSLLVP+A V AR+CL VD L+DDV++ AR +L+PA Sbjct: 1077 ALLDRHATLRLRVQDSD---GEWSLLVPDAATVDARDCLSVVDTLSDDVVLAARAKLNPA 1133 Query: 721 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 780 AGAMVSA+WVR+TSQLVL+IHHLAVDGVSWRILLEDLNIAWAQH +GQ ++LPAGGTSF Sbjct: 1134 AGAMVSALWVRQTSQLVLIIHHLAVDGVSWRILLEDLNIAWAQHHSGQQVQLPAGGTSFL 1193 Query: 781 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL 840 RWS LA+HA T V ADAWR + + P ALP VQPDTDT+ +AG+ SA+LD ETTRQL Sbjct: 1194 RWSKRLADHAHTAEVTAQADAWREILAKPAALPAVQPDTDTHASAGRFSATLDPETTRQL 1253 Query: 841 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW 900 LGEVPAAF AGVQDILLVAFGLAW EFLNRS TPI VDVEGHGR++ELASD+DLSRTVGW Sbjct: 1254 LGEVPAAFHAGVQDILLVAFGLAWAEFLNRSGTPITVDVEGHGRHEELASDIDLSRTVGW 1313 Query: 901 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG 960 FTTKYPVALTV ++PW QVVAG+A LG +VK VKEQLR++P+GLTYGLLRYLN EV+LGG Sbjct: 1314 FTTKYPVALTVADVPWAQVVAGEATLGAVVKDVKEQLRAVPDGLTYGLLRYLNSEVELGG 1373 Query: 961 SDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDN 1020 ++PTIGFNYLGRLGAGAGELSEELWRI+Q VPMPL HTVELNAGT+DTD Sbjct: 1374 TEPTIGFNYLGRLGAGAGELSEELWRIEQGSLALTDVVSAVPMPLAHTVELNAGTMDTDK 1433 Query: 1021 GPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQI 1080 GPSL+ASWTWAPS FDE++A RLS+LWFEALAGICAHV+ GGGGLTPSD+APARLTQR+I Sbjct: 1434 GPSLQASWTWAPSVFDEDKAARLSQLWFEALAGICAHVQAGGGGLTPSDIAPARLTQREI 1493 Query: 1081 DELSQRYDVTDVLPLTPVQQGLLFHSTFARGIG--------DDVYAVQLDITITGVLDQH 1132 D+L+ +++V DVLPLTP+QQGLLF + FA G DDVYAVQL IT++G LD Sbjct: 1494 DQLTTQFEVADVLPLTPLQQGLLFQAGFAEAAGAEAAGVPSDDVYAVQLGITLSGSLDPQ 1553 Query: 1133 RLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCA 1192 +LRDAV V+ RHPNLAARFVEQFGEPVQVL+ DP I W++++ D D +E+LCA Sbjct: 1554 QLRDAVQAVIRRHPNLAARFVEQFGEPVQVLSVDPEIGWQFVEFDSGDTGVDERVERLCA 1613 Query: 1193 AERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLP 1252 AERSAVC L E+P FRAALIRT+ N HRFVLT HHIVIDGWSLP+LLQEIFA YF LP Sbjct: 1614 AERSAVCKLGEQPVFRAALIRTADNLHRFVLTIHHIVIDGWSLPVLLQEIFAAYFDQSLP 1673 Query: 1253 AAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRA 1312 +AAPYRNFV WL W VL+GFETPTLVAPP GPRG+ES+R+S TTR Sbjct: 1674 SAAPYRNFVTWLGAQDRDAAQAAWGSVLEGFETPTLVAPPAQAGPRGVESFRLSEATTRT 1733 Query: 1313 LGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTV 1372 LGELARSQHTT+NTVLQAAW QLLM MTGQRDV FGTAVSGRP DLAGA+SMVGLLINTV Sbjct: 1734 LGELARSQHTTVNTVLQAAWAQLLMWMTGQRDVVFGTAVSGRPVDLAGADSMVGLLINTV 1793 Query: 1373 PIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDT 1432 P+RA TTV DLL QLQ HNDT++HEH+ALN+IH ++GH++LFDTLF+YE+YPID Sbjct: 1794 PVRATSGVATTVTDLLGQLQRDHNDTVDHEHMALNEIHRLTGHDRLFDTLFVYENYPIDA 1853 Query: 1433 SAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRL 1492 +A + VQ+LAVT+F +REYNHYPLS++A PGHE+ LRVE+DT +FD + IE L+DR +R+ Sbjct: 1854 NALLSVQDLAVTDFASREYNHYPLSMVATPGHEVVLRVEFDTEIFDAASIEALVDRLRRV 1913 Query: 1493 LEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAP 1552 L+AM DP RRLS++D++D E +LDEW NRAVLT+P + +SIP FA V R P+A Sbjct: 1914 LDAMATDPGRRLSTIDLLDPQEHDRLDEWGNRAVLTRPAPALESIPASFAESVRRVPDAV 1973 Query: 1553 AVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAY 1612 A++ S Y ELDEA+N++A+LLA GA PG+ VA+++PR+ +A+V ILA+LKTGAAY Sbjct: 1974 ALSCGDRSWTYRELDEASNRMAHLLAGRGAKPGERVAMLLPRTGEAVVTILAILKTGAAY 2033 Query: 1613 LPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTP 1672 LPIDP+ P AR+EF+L DA PVAAV++ DL +R + V+EVDDPA+ ST+L P Sbjct: 2034 LPIDPAHPDARIEFVLKDAAPVAAVSSADLCTRLIASGVPVIEVDDPAIGAEASTSLPVP 2093 Query: 1673 SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVW 1732 + DDIAY+IYTSGTTG PKGVA+TH NV Q+LDTL A+L G W+Q HSL FD SVW Sbjct: 2094 AVDDIAYIIYTSGTTGTPKGVAVTHRNVAQLLDTLGAQLEL--GQTWTQCHSLAFDYSVW 2151 Query: 1733 EIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSP---------E 1783 EIWG LL+GGRL++VP+++ SP+DLHA+LV+E V++L QTPSA + E Sbjct: 2152 EIWGPLLNGGRLLMVPDAVVRSPEDLHAMLVAEQVSMLSQTPSAFYALQTADALYPERGE 2211 Query: 1784 GLEGTALVVAGEACPTEVVDRW-----AVDRVMINAYGPTESTIYAAIS--APLSPGSDV 1836 L+ +V GEA + W + R MIN YG TE+T++A+ + Sbjct: 2212 QLKLQTVVFGGEALEPHRLSGWMHAHPGMPR-MINMYGITETTVHASFREIGEADLANST 2270 Query: 1837 VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEP 1896 PIG P+ + FVLD WLR VP GVVGELY+A LT TRFVACPFG P Sbjct: 2271 SPIGVPLEHLSFFVLDGWLRQVPVGVVGELYVAGEGLACGYISRSDLTSTRFVACPFGAP 2330 Query: 1897 GARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARE 1956 GARMYRTGDLVRWG DGQLQY+GRADEQVKIRGYRIELGE+ AAL +DGV+QA VIARE Sbjct: 2331 GARMYRTGDLVRWGADGQLQYVGRADEQVKIRGYRIELGEVHAALVGLDGVEQAAVIARE 2390 Query: 1957 DRP 1959 DRP Sbjct: 2391 DRP 2393 Score = 696 bits (1795), Expect = 0.0 Identities = 426/988 (43%), Positives = 552/988 (55%), Gaps = 27/988 (2%) Query: 1125 ITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD 1184 I GV+D L+ A+ + A F E G+ Q + D+R D P+ Sbjct: 38 IDGVVDHGLLQQAIRQALQEAEPARATFFEADGQVFQKPLDYSELEVPLYDVRDAD-DPE 96 Query: 1185 HEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFA 1244 + ++ A + L R + AL +T Q HHI +DG + ++ + I Sbjct: 97 AKAREMAAEIQHTPLPLTGR-LVKFALFQTRDEQFYLFGLGHHISVDGLGMALVSRRIST 155 Query: 1245 GYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG-------VPGP 1297 Y P F + + D + PP P P Sbjct: 156 IYTSLVTGKPVPEAYFGSLRDLVECEMSYESSADYQDDLAYWSENLPPDTGLDQGLAPTP 215 Query: 1298 RGIESYRVSAET------TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRD-VAFGTA 1350 G +Y SA + EL+++ +V AA L + D VA Sbjct: 216 HGKNAYTPSASVPMDPAIVGRIKELSKTLRIRRYSVTTAACALLAQSWSSTGDQVALDFP 275 Query: 1351 VSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHL---ALN 1407 VS R + ++++ +L P+ TVG+ + + + L+H+ L Sbjct: 276 VSRRVS--PESKTLPAMLAGVAPLVLDAPPQLTVGEFCKHVDIRIRELLQHQRFPVHRLG 333 Query: 1408 DIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELG 1467 D + G Q + L + T F G E + N+ H+ L + G EL Sbjct: 334 DGGALRGPRQASNRLAVNFIPSRLTLDFAGA-EATASYTNHGPMGHFGLFFIG-AGEELF 391 Query: 1468 LRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 L F E+ L +R ++ AM DPA L+++ ++ + E +L N + L Sbjct: 392 LSTAGAGQPFANFEVPELAERLGAIVAAMAADPAMPLAAVRLLAESESDRLATIGNHSAL 451 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 ++ SIPE FA +V P+A A+TFEG +L Y ELDEAAN+ A+ L G PG Sbjct: 452 SESAPDAVSIPERFAARVAEAPDAAALTFEGRTLTYRELDEAANRFAHALLARGIGPGSR 511 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VALM PR+ +++AIL K GAAY+P+DP+VPAAR+ F+L DA PVA VTT +LRSRFD Sbjct: 512 VALMSPRTDRSVIAILGAFKAGAAYVPVDPAVPAARVRFILDDASPVAVVTTAELRSRFD 571 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 G DL V+++DDPA+ P+T + P PDDIAY+IYTSGTTG PKGVA+TH N+T ++ L Sbjct: 572 GHDLAVIDIDDPAIASLPATAVSDPRPDDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVL 631 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 LP PG VW HSL FD SVWEI ALL GGRLV+VPE++AGSP+D H LLV+E V Sbjct: 632 EERLPK-PG-VWPLCHSLAFDASVWEISNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQV 689 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAIS 1827 L QTPSAV M+SP+GLE L V GEACP +VDRWA +R MINAYGPTE+TI S Sbjct: 690 TFLTQTPSAVAMLSPDGLESMTLAVVGEACPPALVDRWATNRTMINAYGPTETTICVTSS 749 Query: 1828 APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTR 1887 +PL PGS VVPIGS +P+ A FVLD WLRPVP GV GELY+A LT +R Sbjct: 750 SPLEPGSVVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVTCGYIGRSGLTASR 809 Query: 1888 FVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGV 1947 FV CPFGEPGARMYRTGDLVRWG DGQL+YLGRADEQVKIRGYRIELGE+Q+AL+ +DGV Sbjct: 810 FVPCPFGEPGARMYRTGDLVRWGRDGQLEYLGRADEQVKIRGYRIELGEVQSALAALDGV 869 Query: 1948 DQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGK 2007 + A I REDRPGD+RLVGYITGTADP R+EL +RLP YMVP A+V L LPLT + K Sbjct: 870 ESAAAIMREDRPGDRRLVGYITGTADPVDIRAELADRLPPYMVPTAIVVLPALPLTSSNK 929 Query: 2008 LDRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMR 2066 LD RALPAPEY +A++ YRAP E+ LA I+A VLGVER +M+ Sbjct: 930 LDTRALPAPEYANAEKNYRAPSNPVEEVLADIYAQVLGVERIGVDDSFFDLGGDSILSMQ 989 Query: 2067 VTAAVNTALDADLSVRTLFEAPTVAKLS 2094 V A A R +F TVA+L+ Sbjct: 990 VVARARAA-GIQCRPRDVFVEQTVARLA 1016 >tr|B1MLB4|B1MLB4_MYCA9 Tax_Id=561007 SubName: Full=Probable non-ribosomal peptide synthetase PstA;[Mycobacterium abscessus] Length = 8108 Score = 2484 bits (6439), Expect = 0.0 Identities = 1281/2112 (60%), Positives = 1530/2112 (72%), Gaps = 21/2112 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA P+ R L DLLD+DE ++ V GN A L P ++ LFAE+V R P+AVA+ Sbjct: 2984 ITANPAAR-LSVVDLLDDDERCRLSVLGNHATLARTPSRPASVTGLFAEKVSRTPEAVAV 3042 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G+RSWTYRELD A+NRLAH+L + GA PG VA L RS EAI +IL +LKTGAAYLP Sbjct: 3043 SCGERSWTYRELDSAANRLAHLLIDQGAGPGQVVALLSNRSAEAIAAILGILKTGAAYLP 3102 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDA-----L 175 +DPA PDAR+ F+++DA PV A+TT DL RLD LA+ID+ + P DA + Sbjct: 3103 IDPAVPDARLTFVLADAGPVVAVTTTDLADRLDGRGLAIIDIR--GVGPHPPDAGFDGAI 3160 Query: 176 SGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDV 235 P PD AY+ YTSGTTGVPK VA++H NVTQL+ +L A LP PG VWS HSL FDV Sbjct: 3161 PDPEPDHTAYLIYTSGTTGVPKGVALSHRNVTQLLDSLDAGLPH-PG-VWSHSHSLAFDV 3218 Query: 236 SVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTT 295 SVWEI+GALL GGR+V+ E SSP+DLH LLI E V+V+ QTPSAA L EGL+S Sbjct: 3219 SVWEIFGALLSGGRVVIASEGATSSPEDLHALLIREHVTVITQTPSAARALPREGLDSAA 3278 Query: 296 LIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLF 355 L+V GEACP E+VD+WAPGRVMINAYGPTE T+ A+S PL LF Sbjct: 3279 LVVVGEACPAEVVDQWAPGRVMINAYGPTETTMCVAISAPLTAGQGVPIGTPVTGAA-LF 3337 Query: 356 VLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRW 415 VLD+ LR P GVVGELYVAG GV GY+GR LT++RFVACPFG+ G RMYRTGDLV W Sbjct: 3338 VLDESLRQVPVGVVGELYVAGRGVGYGYVGRAPLTSTRFVACPFGDPGTRMYRTGDLVCW 3397 Query: 416 GSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT 475 DGQL YLGRADEQVKIRG+RIEL EIQA LA L GV++AVVIAREDRPGDKRLVGYIT Sbjct: 3398 RPDGQLNYLGRADEQVKIRGHRIELAEIQAVLASLGGVEEAVVIAREDRPGDKRLVGYIT 3457 Query: 476 GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPS 535 GTAD LR A+A+ LPAYMVP AVV LD IPLTVNGKLD RALPAP+Y YRAP+ Sbjct: 3458 GTADCGGLRMAIADRLPAYMVPAAVVRLDAIPLTVNGKLDTRALPAPDYGDHGR-YRAPA 3516 Query: 536 TPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQT 595 E++LAD+YAQVLG+ERV VDDSFFDLGGDSILSMQVV+R RAAG+ CRPRDIFVEQT Sbjct: 3517 NAVEEVLADIYAQVLGLERVSVDDSFFDLGGDSILSMQVVSRGRAAGLLCRPRDIFVEQT 3576 Query: 596 XXXXXXXXXXXXESH-VVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDD 654 S +DEG+G VV PIM WL+ +DGP +FNQ+V+ QAP GV EDD Sbjct: 3577 VARLARVVQVTAGSRGPIDEGLGHVVPLPIMLWLKGIDGPIEEFNQSVLVQAPEGVAEDD 3636 Query: 655 VVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEAR 714 VV +LQ+LLDRHA LRLRV + WSL VPE G+V A CL T + L+D +V AR Sbjct: 3637 VVTLLQSLLDRHAMLRLRVSG--DGVGGWSLTVPEPGSVDAATCLHTAEYLSDSAVVTAR 3694 Query: 715 NRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPA 774 +RLDPAAG M+SA+WV TSQLV+++HHLAVDGVSWRILLED+N+ WAQH GQS+ LPA Sbjct: 3695 SRLDPAAGVMLSALWVTSTSQLVMIVHHLAVDGVSWRILLEDINLGWAQHRDGQSVVLPA 3754 Query: 775 GGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDV 834 GTSF RW+ LL A V + A WR V++ P P V+PDTDT+ TAGQLS SLDV Sbjct: 3755 AGTSFRRWAELLTALAHDPGVVEHARTWREVSAAPAIFPAVRPDTDTHETAGQLSVSLDV 3814 Query: 835 ETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDL 894 ETTR LLG VPAAF G QDILL+AFGLA EF +DTPIG+DVE HGR++E+A+ +DL Sbjct: 3815 ETTRMLLGAVPAAFHTGPQDILLIAFGLALAEFA-ATDTPIGIDVESHGRHEEIAAGIDL 3873 Query: 895 SRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNP 954 SRTVGWFT KYPV+L+ + W VVAG+ ALG +K KEQLR PEGLT+GLLRYLNP Sbjct: 3874 SRTVGWFTAKYPVSLSGRGVRWSDVVAGNEALGAALKDAKEQLRGQPEGLTFGLLRYLNP 3933 Query: 955 EVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAG 1014 +L SDPT+GFNYLGRL GA +S++LWRI +PMPL HTV LNAG Sbjct: 3934 GANLATSDPTVGFNYLGRLAGGAAAMSDDLWRIPADGMSAVSVAAAIPMPLTHTVALNAG 3993 Query: 1015 TIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPAR 1074 ++TD+GP L+A+WTWA SA D +Q +RLS+LWF+AL GICAHVR GGGGLTPSD+ PAR Sbjct: 3994 AVETDDGPQLQANWTWASSALDRDQVSRLSQLWFDALTGICAHVRAGGGGLTPSDITPAR 4053 Query: 1075 LTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRL 1134 L+QRQ+DEL Q+Y + DVLPLT +QQGL+FHS G D+Y VQLDITI G L+ RL Sbjct: 4054 LSQRQLDELQQQYLIADVLPLTALQQGLVFHSGAGNGPEGDLYVVQLDITIDGALEPERL 4113 Query: 1135 RDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGD--DLTPDHEIEQLCA 1192 AVHTV ARHP+LAARF QF +PVQ++ A+P + WRY+DL + D E+++LCA Sbjct: 4114 HGAVHTVAARHPHLAARFCGQFEQPVQLIPAEPTVGWRYVDLSAEWNCADKDEELQRLCA 4173 Query: 1193 AERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLP 1252 AER+AVCDL E P FR ALIR + ++RFVLT HHIV+DGWSLPILLQEIFA Y G RLP Sbjct: 4174 AERAAVCDLTEPPAFRVALIRVAAERYRFVLTNHHIVLDGWSLPILLQEIFAAYRGQRLP 4233 Query: 1253 AAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPG--PRGIESYRVSAETT 1310 AA P+RNFV+WL W EVL GF+TPTLV PP G RG+ ++++S T Sbjct: 4234 AATPFRNFVSWLAARDTAAAQAAWGEVLAGFQTPTLVGPPQKSGLGRRGVRTHQLSGRLT 4293 Query: 1311 RALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLIN 1370 ALGELAR+QHTT+NTVLQ AW LL +TGQ+DV FG+ VSGRPAD+ GAESMVGLLIN Sbjct: 4294 GALGELARAQHTTVNTVLQGAWALLLTSLTGQQDVVFGSVVSGRPADVPGAESMVGLLIN 4353 Query: 1371 TVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPI 1430 TVP+RA +SA TT LL QL H TLEH+H+ L++IH ++ E+LFDTLF++E+YP+ Sbjct: 4354 TVPVRANISAATTTAGLLDQLTKEHAKTLEHQHVPLSEIHRIAEQERLFDTLFVFENYPV 4413 Query: 1431 DTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQ 1490 DT G A+ E + E YPL++ A+PG EL LR+EYDT++FDV IET + R + Sbjct: 4414 DTGVLSGADGFAIDEIISHESTDYPLTMQAIPGGELRLRIEYDTALFDVCGIETFVKRIE 4473 Query: 1491 RLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPE 1550 +L AM+ DP R LS++ ++D+ ER +L W N+ VLT + P SIPE+FARQV R P+ Sbjct: 4474 SVLSAMVADPRRPLSAVQILDETERDRLQRWGNQGVLTH-LAQPASIPELFARQVTRSPK 4532 Query: 1551 APAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGA 1610 + A+ E SL Y LDEA+N+LA L G PG+ VALM PRSA+A+VAILAVLKTGA Sbjct: 4533 SIALVCEDRSLTYLALDEASNRLARFLIGRGVGPGERVALMFPRSAEAVVAILAVLKTGA 4592 Query: 1611 AYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLL 1670 AYLPIDP++P AR+EFM+ DA P+A VTT L RF GF L VV+V DPA+ L Sbjct: 4593 AYLPIDPALPGARVEFMVSDAGPMAVVTTAALAERFSGFGLPVVDVQDPAIAAECGAGLT 4652 Query: 1671 TPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVS 1730 PS D +A++IYTSGTTG+PKGVA+T NVTQ+ D+L +P PG VW+Q+HS FD S Sbjct: 4653 MPSADGMAHIIYTSGTTGLPKGVAVTQRNVTQLFDSLQIGVPLEPGQVWTQFHSYSFDFS 4712 Query: 1731 VWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTAL 1790 VWEIWGALLHGGRLV+VPE+IA S D H LLV E V VL QTPSAV M+ +GL+ L Sbjct: 4713 VWEIWGALLHGGRLVVVPETIARSSRDFHRLLVREQVTVLTQTPSAVSMLPVDGLDVATL 4772 Query: 1791 VVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFV 1850 V+ E C E+VDRWA R M+N YGPTE+T++ SAPL+PG PIGSP A FV Sbjct: 4773 VIGAEPCSPELVDRWAPGRTMVNVYGPTETTMWLCASAPLAPGLGAPPIGSPTAWAAFFV 4832 Query: 1851 LDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWG 1910 LDEWLRPVP GVVGELYL LT RF+ACPFGEPG+RMYRTGDLVRW Sbjct: 4833 LDEWLRPVPAGVVGELYLGGAGVGIGYWRRSGLTAARFMACPFGEPGSRMYRTGDLVRWR 4892 Query: 1911 DDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITG 1970 DGQL YLGRADEQVKIRGYRIELGEIQ+AL+ +DGV+ A VIAREDRPGDKRLVGYITG Sbjct: 4893 ADGQLDYLGRADEQVKIRGYRIELGEIQSALAALDGVENAAVIAREDRPGDKRLVGYITG 4952 Query: 1971 TADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETE 2030 ADP AR+ L RLP YMVPAAVV L LP+TVNGKLD RALPAP+YQ RYRAP Sbjct: 4953 AADPVGARTALAERLPGYMVPAAVVGLAALPMTVNGKLDVRALPAPDYQDVDRYRAPVGA 5012 Query: 2031 TEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTV 2090 ++ LAGI+A VL VER MR+ AAVN AL+ADLS RT+F+APT+ Sbjct: 5013 VQEILAGIYARVLDVERVGVDDSFFDLGGDSVSTMRLVAAVNAALNADLSTRTVFDAPTI 5072 Query: 2091 AKLSLHVEHDAG 2102 A+L+L + AG Sbjct: 5073 AQLALRIGEGAG 5084 Score = 2380 bits (6167), Expect = 0.0 Identities = 1241/2129 (58%), Positives = 1522/2129 (71%), Gaps = 46/2129 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P R L + D+ E + Q+++W NR LT P P P++IP LFAEQVVR P AVA+ Sbjct: 420 MTADPR-RPLSAIDVRAEAQCPQLDLWSNRGALTHPVPRPLSIPELFAEQVVRDPGAVAV 478 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G RS +YR LDEASNRLAH+L HG PG VA L+ RS EA+++I+ VLKTGAAY+P Sbjct: 479 SCGGRSVSYRGLDEASNRLAHLLISHGVGPGQRVALLLSRSVEAVVAIMGVLKTGAAYVP 538 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALS-GPR 179 +DP+ PDAR+ F++ DA PV +TTA+L RL + L V+D+ A+ +PS ALS P Sbjct: 539 IDPSVPDARLRFVLCDAGPVVVVTTAELADRLAGHGLTVVDIDGRAVYGQPSAALSIMPH 598 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWE 239 PDD+AY+ YTSGTTG PK VA+ HHNVT+L+ A+ ADL PGQ W+Q HSL FD SVWE Sbjct: 599 PDDVAYLIYTSGTTGTPKGVAIPHHNVTRLLEAIDADLELVPGQGWAQCHSLAFDFSVWE 658 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGML------SPEG--L 291 I+GALLHGGRLVVVPE V +P++LH LL+ E+VSVL QTPSA L SPE L Sbjct: 659 IFGALLHGGRLVVVPEGVTRAPEELHALLVHERVSVLSQTPSAFYALHAVDTASPEQRQL 718 Query: 292 ESTTLIVAGEACPTELVDRWAPGRV----MINAYGPTEATIYAAMSEPLXXXXXXXXXXX 347 + ++ GEA + W +IN YG TE T++A+ E Sbjct: 719 ALSVVVFGGEALEPARLSDWFQDHPQSPRLINMYGITETTVHASFREITVSDVVGTSSPI 778 Query: 348 XXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 L FVLD WLRP G VGELYVAG GV GY GR LTA+RFVACPFG G R Sbjct: 779 GAPLADLSFFVLDDWLRPLQAGAVGELYVAGAGVGYGYAGRTSLTATRFVACPFGGRGTR 838 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDLV WGSDGQL YLGRADEQVKIRGYRIELGE+Q+ALA L+GVDQ VIAREDRP Sbjct: 839 MYRTGDLVCWGSDGQLRYLGRADEQVKIRGYRIELGEVQSALAALEGVDQVAVIAREDRP 898 Query: 466 GDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 GDKRLVGY TG+ADP +LR L + LP+YMVP A+VVL+++PLTVNGKLDR ALPAPEYR Sbjct: 899 GDKRLVGYFTGSADPGELRETLTDRLPSYMVPAAIVVLESLPLTVNGKLDRNALPAPEYR 958 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQC 585 A YR P+T E+ LA +YAQVLG+ERVG DDSFF+LGGDSIL+MQV + R AG+ C Sbjct: 959 -AVERYRRPATVVEETLAAIYAQVLGLERVGADDSFFELGGDSILAMQVSSAVRMAGLAC 1017 Query: 586 RPRDIFVEQTXXXXXXXXXXXXE-SHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVIT 644 RPRDIFV+QT + +DEG GPV ATPIMRWL+E+ GP +FNQTV+ Sbjct: 1018 RPRDIFVQQTVARLAEVVVAGDTIAEPLDEGTGPVTATPIMRWLKEIGGPVAEFNQTVVL 1077 Query: 645 QAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA 704 QAP GVT V+ +LQA+LDRHA LRLR ED W L GAV A +CL ++D Sbjct: 1078 QAPDGVTGAAVIAMLQAVLDRHAMLRLRAED--HGNGGWLLSAAAPGAVEAAQCLESIDR 1135 Query: 705 LTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 LTD+ L+ AR+RLDPAAGA++S +WV T +LVL++HHLAVDGVSWRILLEDLNIAW Q Sbjct: 1136 LTDEALLAARSRLDPAAGAVLSGLWVDSTHRLVLIVHHLAVDGVSWRILLEDLNIAWTQQ 1195 Query: 765 CTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVT 824 G+ I LP GTSF +W+ LL+E+ +++ V + A W+ V++VP LPPV P+ DTY T Sbjct: 1196 QDGRPIALPRPGTSFRQWAELLSEYTRSEPVVEQAQRWQTVSAVPALLPPVDPEADTYET 1255 Query: 825 AGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGR 884 AGQLSA+LD ETTR LLG VPAAF AG Q+ILL+A GLA EF T I +DVEGHGR Sbjct: 1256 AGQLSAALDTETTRLLLGAVPAAFHAGPQEILLIALGLALAEF--SGTTQIAIDVEGHGR 1313 Query: 885 YDEL-------ASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQL 937 ++EL A +DLSRTVGWFTTKYPV+L ++ L W VVAGDAALG ++KA KEQ Sbjct: 1314 HEELGELSGAGARSIDLSRTVGWFTTKYPVSLDLDGLAWSSVVAGDAALGAMIKAAKEQA 1373 Query: 938 RSLPEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGA--GAGELSEELWRIDQXXXXXX 995 R+LP+GLTYGLLRYLNP VDL SDP+I FNYLGR+ GAG W++ Sbjct: 1374 RALPDGLTYGLLRYLNPAVDLAASDPSIAFNYLGRVSGLTGAG------WQLCPDSASLS 1427 Query: 996 XXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGIC 1055 VP PL H +ELNA I+T+ G L A WTWA SA D+ Q RL+ LWF+AL GIC Sbjct: 1428 RAASRVPTPLGHPLELNAIVIETEAGVLLNADWTWARSALDQTQVGRLNELWFQALTGIC 1487 Query: 1056 AHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDD 1115 AHVR GGGGLTPSD+APA L Q QIDELS+++ TD+LPLTP+QQGLL+HS ARG DD Sbjct: 1488 AHVRSGGGGLTPSDIAPAVLNQGQIDELSRQHHFTDLLPLTPLQQGLLYHSGTARGC-DD 1546 Query: 1116 VYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYL- 1174 VYA+QL + + G LD +LRDAV +VV RHP+LAARF E+F P+Q + DP++ W+YL Sbjct: 1547 VYAMQLSLVLDGQLDPQQLRDAVQSVVDRHPHLAARFYERFDPPIQAIPTDPVVPWQYLA 1606 Query: 1175 -DLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGW 1233 D G D+ D +++++ AAER AV DL R RAALIRT+ QHRF+LT HHIV+DGW Sbjct: 1607 LDFNGTDI--DGQVQEISAAERVAVGDLANRCAIRAALIRTADEQHRFILTTHHIVLDGW 1664 Query: 1234 SLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAP-- 1291 S+PIL+QEIFA G RL AA YR+FV WL WR+ + GF+ PTLV P Sbjct: 1665 SMPILIQEIFASLRGQRLRPAASYRSFVTWLSERDQVAAQHAWRKAMAGFDAPTLVGPST 1724 Query: 1292 PGVPGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAV 1351 P PG RG+ES+++ E T+ +GELARS+ TT+N VLQ AW LL + G DVAFGT V Sbjct: 1725 PDGPGHRGVESFQLPEEITKNVGELARSRQTTVNVVLQGAWALLLSSLCGHGDVAFGTTV 1784 Query: 1352 SGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHH 1411 SGRPA++ GAESMVGLLINTVP+RA + A TT +LL QLQ HNDTLEH+HLAL+DIH Sbjct: 1785 SGRPAEVLGAESMVGLLINTVPVRATIGAATTTAELLGQLQGRHNDTLEHQHLALSDIHR 1844 Query: 1412 VSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVE 1471 ++G E+LFDTL ++E+YPID + ++ LAVT F+ RE NHYPL+V LPG LGLR+E Sbjct: 1845 ITGQERLFDTLMVFENYPIDVTERWDIEGLAVTGFDFRESNHYPLAVQVLPGSALGLRIE 1904 Query: 1472 YDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPV 1531 YD+ VFD + ++ L R +L AM DP LSS+D++DD RTQLD W+ R L P Sbjct: 1905 YDSGVFDCAAVKALFGRLTTILSAMTADPGLPLSSIDLLDDAVRTQLDTWSGRESLIDP- 1963 Query: 1532 DSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALM 1591 + +SIPE+F QVER P A AVT +G SL Y ELDE+AN+LA +LA GA G++VAL+ Sbjct: 1964 PAVKSIPELFGEQVERSPGAIAVTCDGRSLTYRELDESANRLARVLADRGAGSGETVALL 2023 Query: 1592 VPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDL 1651 RSA+AIVA+LAVLKTGAAY+P+DP++P AR+EFM+ D P+ AVTT + R R +L Sbjct: 2024 FSRSAEAIVAMLAVLKTGAAYVPVDPALPLARIEFMVADTAPILAVTTTEHRPRLGDIEL 2083 Query: 1652 QVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAEL 1711 ++++++P+ ++ T P+PDDIAY+I+TSGTTG PKGVAI H NV + D L A++ Sbjct: 2084 CIIDINEPSPDVQAETAPPGPTPDDIAYIIFTSGTTGTPKGVAIAHRNVPGLFDALNAQV 2143 Query: 1712 PAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLY 1771 P+G G VW+QWHS FDVSVWEI+GALLHG L++V E A SP +LH LLV++ V+VL Sbjct: 2144 PSGTGQVWAQWHSYSFDVSVWEIFGALLHGACLLVVTEQAAASPGELHELLVTQRVSVLS 2203 Query: 1772 QTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLS 1831 QTPSA M+SP+GLE TALVVAGEACP E+VDRWA RVM+NAYGPTE+T+YA+ISAPL Sbjct: 2204 QTPSAAGMISPQGLESTALVVAGEACPPELVDRWAPGRVMVNAYGPTEATVYASISAPLQ 2263 Query: 1832 PGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVAC 1891 GS V+ IG+PVP A FVLD+W+RP PPGV GELY+A LT TRFVAC Sbjct: 2264 SGSPVL-IGAPVPGVALFVLDQWMRPAPPGVAGELYVAGRGVGLGYWRRTGLTSTRFVAC 2322 Query: 1892 PFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAV 1951 PFGEPG RMYRTGDLV+W D GQL+YLGRADEQVKIRGYRIELGE+QAAL+ +DGV QAV Sbjct: 2323 PFGEPGGRMYRTGDLVQWDDGGQLRYLGRADEQVKIRGYRIELGEVQAALATLDGVTQAV 2382 Query: 1952 VIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRR 2011 VIA ED+ G RLVGY+ G ADP R++L RLP YMVPAAVV ++ LPLTV+GKLDRR Sbjct: 2383 VIAHEDQGGTLRLVGYVVGKADPDRIRTQLAARLPGYMVPAAVVVIDALPLTVSGKLDRR 2442 Query: 2012 ALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAV 2071 ALPAP+Y A RYRAP TE+ L I+A VLG ER AMR+ A + Sbjct: 2443 ALPAPDYVDAARYRAPSNPTEEILTDIYARVLGHERVGIDDSFFDLGGDSLSAMRLLAGI 2502 Query: 2072 NTALDADLSVRTLFEAPTVAKLSLHVEHD 2100 N AL+ ++VRTLF+APTVA+L + D Sbjct: 2503 NAALNTGVTVRTLFDAPTVAQLCTRISRD 2531 Score = 1778 bits (4604), Expect = 0.0 Identities = 913/1525 (59%), Positives = 1115/1525 (73%), Gaps = 43/1525 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+ +R L S D+LD EH +++ GNRA+L PVT+PALFA+QV R P+AVA+ Sbjct: 6593 MTADVESR-LSSIDVLDPAEHARLDSMGNRALLEQRAINPVTVPALFADQVARTPEAVAV 6651 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 G + TYRELD+A+N LA L+ G PG VA L+ RS +AI+++L+VLK GAAYL Sbjct: 6652 TCGGHALTYRELDDAANWLALRLSRAGVVPGGCVALLLERSSQAIVAMLAVLKAGAAYLA 6711 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMA------DPAIDRRPSDA 174 +DP P ARI FM+ DA P A +TT+ L R D +++VID+ D ++ S A Sbjct: 6712 IDPVMPSARIDFMLDDAAPTAVVTTSGLAGRFDGREMSVIDIGELADVDDAEMEIVHSPA 6771 Query: 175 LSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFD 234 GP PDD+AY+ YTSGTTGVPK VAVTHHN+T L + A LP+ QVW+Q HS FD Sbjct: 6772 NPGPEPDDIAYLIYTSGTTGVPKGVAVTHHNLTHLARSTPAQLPAN--QVWTQCHSYAFD 6829 Query: 235 VSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLEST 294 SVWEIW ALL G R+VVVPES+ SSP+D H LL+ E+V+VL QTPSAAG LSP GL+S Sbjct: 6830 FSVWEIWAALLGGARVVVVPESIVSSPEDFHTLLVRERVNVLTQTPSAAGALSPAGLDSV 6889 Query: 295 TLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXL 354 L++ GEACP E+VDRWA G +INAYGPTE T+YA+MS PL L Sbjct: 6890 ALLLGGEACPGEVVDRWAAGHTVINAYGPTEITVYASMSAPLAAGSGAAPIGAPVSTSAL 6949 Query: 355 FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVR 414 FVLD+WLRP P GVVGELYVAG GVA GY+GR LT++RFVACPFG G RMYRTGDLV Sbjct: 6950 FVLDEWLRPVPVGVVGELYVAGEGVACGYLGRSGLTSARFVACPFGVPGARMYRTGDLVS 7009 Query: 415 WGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYI 474 W DGQL+Y GRAD+QVKIRGYRIELGE+QAAL+ L V QA VIARED PG RLVGY+ Sbjct: 7010 WRPDGQLQYRGRADDQVKIRGYRIELGEVQAALSALSDVSQAAVIAREDPPGVTRLVGYV 7069 Query: 475 T----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAAND 530 T G A+P +LR ALA +P YMVP+A+VVL+ +PLTVNGKLD RALPAPEY+ A Sbjct: 7070 TESVNGVAEPDRLRNALANRVPGYMVPSAIVVLEALPLTVNGKLDIRALPAPEYQDAER- 7128 Query: 531 YRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDI 590 YRAP+ E+ LA +YAQVLG++RVGVDDSFFDLGGDSILSMQVVARARA G+ CRPRDI Sbjct: 7129 YRAPADAVEETLAGIYAQVLGLDRVGVDDSFFDLGGDSILSMQVVARARACGVVCRPRDI 7188 Query: 591 FVEQTXXXXXXXXXXXXE-SHVVDEGVGPVVATPIMRWLREVDG---PTGQFNQTVITQA 646 FVEQT E S VDEGVGPV ATPIMRWLR+V+G PT QFNQT + QA Sbjct: 7189 FVEQTVARLAQVVGVVDEDSGPVDEGVGPVAATPIMRWLRDVEGTGAPTDQFNQTAVIQA 7248 Query: 647 PAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALT 706 PAG +E DV ++L ALLDRHA LRLRVE+ W L VPE CL++V+ LT Sbjct: 7249 PAGASESDVEMVLGALLDRHAMLRLRVEN-------WMLQVPEQTLTAP--CLQSVEVLT 7299 Query: 707 DDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCT 766 D L+ AR RL+PAAG MVSA+WV T QLVL+IHHLA+D VSWRILLEDLNIAW QH Sbjct: 7300 DAELLAARARLNPAAGQMVSALWVASTGQLVLVIHHLAIDAVSWRILLEDLNIAWGQHRH 7359 Query: 767 GQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAG 826 GQ + LP GTSFARW+ALL EHA V D D WR V + P ALP P+ DTY +AG Sbjct: 7360 GQPVALPKAGTSFARWAALLEEHAYDRDVVDQTDRWRRVLATPPALPAACPELDTYASAG 7419 Query: 827 QLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYD 886 +ASLDVETTR LLG VPAAF AGVQDILL+ + LA TEFL + P+G++VEGHGR + Sbjct: 7420 HYTASLDVETTRALLGAVPAAFHAGVQDILLIGYALALTEFLGVT-LPVGIEVEGHGRVE 7478 Query: 887 ELA---SDVDLSRTVGWFTTKYPVALTVENLP--------WEQVVAGDAALGGIVKAVKE 935 +L +++DLSRTVGWFTTKYPVAL V P W+QVVAGD LG ++K KE Sbjct: 7479 DLGGCVTEIDLSRTVGWFTTKYPVALAVSGKPGRSAGRLRWDQVVAGDPLLGAVIKDAKE 7538 Query: 936 QLRSLPEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLG---AGAGELSEELWRIDQXXX 992 QLRSLPEG+TYGLLRYLN +VDL G++PT+GFNYLGRLG AG E ++LW++ Sbjct: 7539 QLRSLPEGMTYGLLRYLNSDVDLTGAEPTVGFNYLGRLGGGGAGRAEFHDQLWQVSPDTA 7598 Query: 993 XXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALA 1052 +PMPL HTVELNA T +T++GPSL A+WTWAPS DE QA RLSRLWF+ALA Sbjct: 7599 AVAAAVTALPMPLTHTVELNASTAETEDGPSLYAAWTWAPSVLDEVQAARLSRLWFDALA 7658 Query: 1053 GICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGI 1112 GICAHVR GGGGLTPSD+ PARLTQR++D+L++ + + DVLPLTP+Q GLLF + +RG Sbjct: 7659 GICAHVRSGGGGLTPSDIVPARLTQRELDDLARDHAIDDVLPLTPLQHGLLFQANTSRGN 7718 Query: 1113 GDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWR 1172 DDVYA+QLDITITG LD RLR+AV VV RHPNLAARF ++F EPVQ++ A+P W+ Sbjct: 7719 SDDVYAMQLDITITGPLDADRLREAVRAVVNRHPNLAARFDKRFDEPVQIIPANPTAPWQ 7778 Query: 1173 YLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDG 1232 +++ + + ++ LCAAER+AVCD++ + FRAALIR N+HRFV+T+HHIV+DG Sbjct: 7779 VVEIDVEQADYEQRLQGLCAAERAAVCDVVNQSAFRAALIRIDENEHRFVMTYHHIVLDG 7838 Query: 1233 WSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPP 1292 WSLPILL+E+FA Y+G RLP A+ YR FV WL W EVL F+ P LVAP Sbjct: 7839 WSLPILLREVFASYYGQRLPVASSYRRFVTWLIERDVDGARRAWCEVLKDFDRPALVAPK 7898 Query: 1293 G-VPGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAV 1351 G +PG R E++R+SA+ + A+G+LARSQHTT NTVLQAAW Q+LM +TG+ DVAFG AV Sbjct: 7899 GRLPGRRATETFRISADISDAVGQLARSQHTTANTVLQAAWAQVLMWLTGRHDVAFGVAV 7958 Query: 1352 SGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHH 1411 SGR A++AGA+SMVGLLINTVP+R V+ DTT+ +LL LQ H+DTLEH+HLAL++I H Sbjct: 7959 SGRSAEVAGADSMVGLLINTVPVRVTVTPDTTIAELLANLQRQHSDTLEHQHLALSEIQH 8018 Query: 1412 VSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVE 1471 G EQLFDTLF+Y++YP+ T A L++T + REYNHYPL++ A+PG+EL LRVE Sbjct: 8019 AVGQEQLFDTLFVYQNYPVQTMASSMPDGLSITAVSGREYNHYPLTLQAMPGNELVLRVE 8078 Query: 1472 YDTSVFDVSEIETLIDRFQRLLEAM 1496 +DT +F S + +++RFQR+LEAM Sbjct: 8079 FDTGLFGESRVRKVVERFQRVLEAM 8103 Score = 781 bits (2017), Expect = 0.0 Identities = 482/1053 (45%), Positives = 617/1053 (58%), Gaps = 63/1053 (5%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 +V+PL+ Q L F VY + + + + G LD L A+ ++ RH +L Sbjct: 5096 EVIPLSFAQNRLWFVDQLQGP--SPVYNMPVGLRLYGRLDAAALGAALSDLIGRHESLRT 5153 Query: 1151 RFVEQFGEPVQVLTADPMI--AWRYLDLRGDDLTPDHEIEQLCAAERSAVC---DLLERP 1205 RF G P Q++ D I W +D + QL A + VC DL Sbjct: 5154 RFDAPGGNPRQIVLPDGPIDFGWEIID------ATSWQTGQLDEAIAATVCRSFDLAIEI 5207 Query: 1206 TFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYF----GHR---LPAAAPYR 1258 A + R + +H V HHI DGWSL L+ ++ Y GH P Y Sbjct: 5208 PLYARVFRIAEEEHVLVAVVHHIAADGWSLTPLMHDLSVAYASRCRGHAPDWAPLPVQYV 5267 Query: 1259 NFVNWLXXXXXXXXXXX---------WREVLDGFET----PTLVAPPGVPGPRGIE-SYR 1304 ++ W W L G PT P V RG + Sbjct: 5268 DYTLWQRAQLGDLGDGDSPISAQLAYWEGALAGLPERVALPTDRPYPPVADQRGSTVEVQ 5327 Query: 1305 VSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESM 1364 E + + AR T V+QA+ LL ++G DVA G ++GR D A + + Sbjct: 5328 WPPELQQQVRATAREHGATSFMVMQASLAVLLASISGTSDVAVGFPIAGR-RDTA-LDQL 5385 Query: 1365 VGLLINTVPIRAKVSADTTVGDLL-----RQLQSHHNDTLEHEHLA--LNDIHHVSGHEQ 1417 VG +N + +R +S D TV +LL R L ++ N + E L LN I ++ H Sbjct: 5386 VGFFVNNLVLRVDLSGDPTVAELLTQVRQRSLAAYENQDVPFEVLVERLNPIRSLA-HHP 5444 Query: 1418 LFDTLFLYESYPI-DTSAFMG-------VQELAVTEFNNREYNHYPLSVM-ALPGHELGL 1468 L +++ P DT G V+ L+V R + L + G G+ Sbjct: 5445 LVQVALAWQNLPWQDTGPADGLRLGDLRVEPLSVDTQTARMDLTFSLGERWTMAGEPAGI 5504 Query: 1469 R--VEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAV 1526 VE+ T VFD IE LI R+QR++ +M DP+RRLSS+DV+D+ E T++D W NR + Sbjct: 5505 AGAVEFRTDVFDADSIEALIARWQRVVASMTADPSRRLSSIDVLDEAEHTRVDRWGNREL 5564 Query: 1527 LTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGK 1586 L +P +S+P +FA Q R P A A++F G L Y E+D+A++QLA+ L G PG+ Sbjct: 5565 LNRPPAVRRSVPALFAEQAARVPHAVAISFNGRELTYREVDQASDQLAHRLIAQGVRPGE 5624 Query: 1587 SVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRF 1646 SVAL+ R +A+VA+LAVLKTGAAYLPIDP++P R+EFM+GDA P AA+TT DL R Sbjct: 5625 SVALLTERCPEAVVAMLAVLKTGAAYLPIDPALPDVRVEFMIGDAAPTAAITTADLTDRL 5684 Query: 1647 DGFDLQVVEVDDPA--VEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVL 1704 G+ L V++V D A ++L PSPDDIAY+IYTSGTTGVPKGVAI H NVT ++ Sbjct: 5685 AGYALTVIDVGDIAEGASSGAGSSLPLPSPDDIAYIIYTSGTTGVPKGVAIAHHNVTALM 5744 Query: 1705 DTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVS 1764 + PA AG W+QWHS FD SV EIWG+LLHGGRLV+VPES A SP+ L ALLV+ Sbjct: 5745 GS-PATFLAGH--TWAQWHSYAFDASVEEIWGSLLHGGRLVVVPESAAHSPEHLTALLVA 5801 Query: 1765 EGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYA 1824 E V L QTPSAV +++PE L+ +L+VAGE CP EVVDRWA R+M+NAYGPTE+TI A Sbjct: 5802 EQVTALSQTPSAVALLTPESLDAVSLLVAGEPCPGEVVDRWAPGRLMVNAYGPTETTICA 5861 Query: 1825 AISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLT 1884 + +A L G+ IG+PVP A FVLD LRPVPPGVVGELY+A LT Sbjct: 5862 SRTAALVGGTGSPSIGAPVPGAAMFVLDGLLRPVPPGVVGELYIAGHGVGVGYAGRTGLT 5921 Query: 1885 GTRFVACPFGE---PGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAAL 1941 +RFVACPF + PG RMYRTGDLVRW DGQL+YLGRADEQVKIRGYRIEL EI + L Sbjct: 5922 ASRFVACPFADAQLPGQRMYRTGDLVRWRADGQLEYLGRADEQVKIRGYRIELAEIHSVL 5981 Query: 1942 SDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLP 2001 + +DGVDQA VIAREDRPGD+RLVGY+TGTA+PA R++L +LPAYMVP AVV L LP Sbjct: 5982 TALDGVDQAAVIAREDRPGDRRLVGYVTGTANPAKLRAQLAEQLPAYMVPVAVVVLAALP 6041 Query: 2002 LTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXX 2061 +TVNGKLD RALP PEYQ RYRAP T TE+ LAGI+A VLGVER Sbjct: 6042 MTVNGKLDTRALPRPEYQDIDRYRAPGTLTEEILAGIYARVLGVERVGVDDSFFDLGGDS 6101 Query: 2062 XXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 AMR+ AAVN L+A +SVRT+FEAPTV +L+ Sbjct: 6102 LSAMRLIAAVNADLNAVVSVRTVFEAPTVGQLA 6134 Score = 760 bits (1962), Expect = 0.0 Identities = 468/1033 (45%), Positives = 590/1033 (57%), Gaps = 65/1033 (6%) Query: 1116 VYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLT--ADPMIAWRY 1173 VY + + I+G LD L + VVARH +L +F G P QV+ AD W Sbjct: 6177 VYNMATALRISGALDVDALGAGLADVVARHESLRTQFRATGGVPQQVVVPAADAHFGWDV 6236 Query: 1174 LDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGW 1233 +D G T E + A R DL A L R +G+++ HHI D W Sbjct: 6237 VDATG--WTTSQLREAIGEAARHTF-DLSNEIPLYARLFRITGDEYVLAAVVHHIAADAW 6293 Query: 1234 SLPILLQEIFAGYFGHRL-------PAAAPYRNFVNWLXXXXXXXXXXX---------WR 1277 S+ L+ ++ Y R P A Y ++ W W+ Sbjct: 6294 SITPLVTDLGVAYVSRRAGHAPGWAPLAVQYVDYTLWQRAEFGDFADGGSRIAAQLDYWQ 6353 Query: 1278 EVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHTTINTVLQAAW 1332 + L G E PT P RG + + A + +AR + T VLQAA Sbjct: 6354 DALAGMPERVELPTDRPYPSTADQRGSTMAVQWPAALQEQIARVAREHNATSFMVLQAAL 6413 Query: 1333 TQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAKVSADTTVGDLL-- 1388 LL +++G DVA G ++GR PA + ++G +NT+ +R +S D TV +LL Sbjct: 6414 GVLLSKLSGNTDVAVGFPIAGRRDPA----LDELIGFFVNTLVLRLDLSGDPTVAELLAQ 6469 Query: 1389 ---RQLQSHHNDTLEHEHLA--LNDIHHVSGHEQLFDTLFLYESYPIDTSAFMG----VQ 1439 R L ++ N + E L LN ++ H L +++ P + G + Sbjct: 6470 VRARSLAAYENQDVPFEVLVERLNPTRSLT-HHPLIQVALGWQNVPGQDNGSSGPGLALG 6528 Query: 1440 ELAVTEFNNREYNHYPLSVMALPGHE--------LGLRVEYDTSVFDVSEIETLIDRFQR 1491 +L VT + +L H +G VE+ T VFD + IE L+ RF+ Sbjct: 6529 DLEVTPMDADTQTARMDLSFSLAEHRTRDGEPAGIGGTVEFRTDVFDPASIERLLGRFEL 6588 Query: 1492 LLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEA 1551 +L AM D RLSS+DV+D E +LD NRA+L Q +P ++P +FA QV R PEA Sbjct: 6589 VLTAMTADVESRLSSIDVLDPAEHARLDSMGNRALLEQRAINPVTVPALFADQVARTPEA 6648 Query: 1552 PAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAA 1611 AVT G +L Y ELD+AAN LA L+ G PG VAL++ RS+ AIVA+LAVLK GAA Sbjct: 6649 VAVTCGGHALTYRELDDAANWLALRLSRAGVVPGGCVALLLERSSQAIVAMLAVLKAGAA 6708 Query: 1612 YLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVE------VDDPAVEIYP 1665 YL IDP +P+AR++FML DA P A VTT L RFDG ++ V++ VDD +EI Sbjct: 6709 YLAIDPVMPSARIDFMLDDAAPTAVVTTSGLAGRFDGREMSVIDIGELADVDDAEMEIVH 6768 Query: 1666 STTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSL 1725 S P PDDIAY+IYTSGTTGVPKGVA+TH N+T + + PA+LPA VW+Q HS Sbjct: 6769 SPANPGPEPDDIAYLIYTSGTTGVPKGVAVTHHNLTHLARSTPAQLPANQ--VWTQCHSY 6826 Query: 1726 VFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL 1785 FD SVWEIW ALL G R+V+VPESI SP+D H LLV E VNVL QTPSA +SP GL Sbjct: 6827 AFDFSVWEIWAALLGGARVVVVPESIVSSPEDFHTLLVRERVNVLTQTPSAAGALSPAGL 6886 Query: 1786 EGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPK 1845 + AL++ GEACP EVVDRWA +INAYGPTE T+YA++SAPL+ GS PIG+PV Sbjct: 6887 DSVALLLGGEACPGEVVDRWAAGHTVINAYGPTEITVYASMSAPLAAGSGAAPIGAPVST 6946 Query: 1846 GATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGD 1905 A FVLDEWLRPVP GVVGELY+A LT RFVACPFG PGARMYRTGD Sbjct: 6947 SALFVLDEWLRPVPVGVVGELYVAGEGVACGYLGRSGLTSARFVACPFGVPGARMYRTGD 7006 Query: 1906 LVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLV 1965 LV W DGQLQY GRAD+QVKIRGYRIELGE+QAALS + V QA VIARED PG RLV Sbjct: 7007 LVSWRPDGQLQYRGRADDQVKIRGYRIELGEVQAALSALSDVSQAAVIAREDPPGVTRLV 7066 Query: 1966 GYIT----GTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSA 2021 GY+T G A+P R+ L NR+P YMVP+A+V LE LPLTVNGKLD RALPAPEYQ A Sbjct: 7067 GYVTESVNGVAEPDRLRNALANRVPGYMVPSAIVVLEALPLTVNGKLDIRALPAPEYQDA 7126 Query: 2022 QRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSV 2081 +RYRAP E+TLAGI+A VLG++R +M+V A A Sbjct: 7127 ERYRAPADAVEETLAGIYAQVLGLDRVGVDDSFFDLGGDSILSMQVVARAR-ACGVVCRP 7185 Query: 2082 RTLFEAPTVAKLS 2094 R +F TVA+L+ Sbjct: 7186 RDIFVEQTVARLA 7198 Score = 750 bits (1936), Expect = 0.0 Identities = 443/931 (47%), Positives = 572/931 (61%), Gaps = 51/931 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+P L S DLLD+ Q++ W R L DP P +IP LF EQV R+P A+A+ Sbjct: 1929 MTADPGL-PLSSIDLLDDAVRTQLDTWSGRESLIDP-PAVKSIPELFGEQVERSPGAIAV 1986 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS TYRELDE++NRLA VLA+ GA G TVA L RS EAI+++L+VLKTGAAY+P Sbjct: 1987 TCDGRSLTYRELDESANRLARVLADRGAGSGETVALLFSRSAEAIVAMLAVLKTGAAYVP 2046 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDPA P ARI FM++D P+ A+TT + R RL +L +ID+ +P+ D + A GP P Sbjct: 2047 VDPALPLARIEFMVADTAPILAVTTTEHRPRLGDIELCIIDINEPSPDVQAETAPPGPTP 2106 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ +TSGTTG PK VA+ H NV L AL+A +PSG GQVW+QWHS FDVSVWEI Sbjct: 2107 DDIAYIIFTSGTTGTPKGVAIAHRNVPGLFDALNAQVPSGTGQVWAQWHSYSFDVSVWEI 2166 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALLHG L+VV E +SP +LH LL+T++VSVL QTPSAAGM+SP+GLEST L+VAG Sbjct: 2167 FGALLHGACLLVVTEQAAASPGELHELLVTQRVSVLSQTPSAAGMISPQGLESTALVVAG 2226 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP ELVDRWAPGRVM+NAYGPTEAT+YA++S PL LFVLD+W Sbjct: 2227 EACPPELVDRWAPGRVMVNAYGPTEATVYASISAPLQSGSPVLIGAPVPGVA-LFVLDQW 2285 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 +RPAP GV GELYVAG GV GY R LT++RFVACPFGE G RMYRTGDLV+W GQ Sbjct: 2286 MRPAPPGVAGELYVAGRGVGLGYWRRTGLTSTRFVACPFGEPGGRMYRTGDLVQWDDGGQ 2345 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L YLGRADEQVKIRGYRIELGE+QAALA LDGV QAVVIA ED+ G RLVGY+ G ADP Sbjct: 2346 LRYLGRADEQVKIRGYRIELGEVQAALATLDGVTQAVVIAHEDQGGTLRLVGYVVGKADP 2405 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 ++RT LA LP YMVP AVVV+D +PLTV+GKLDRRALPAP+Y AA YRAPS P E+ Sbjct: 2406 DRIRTQLAARLPGYMVPAAVVVIDALPLTVSGKLDRRALPAPDYVDAAR-YRAPSNPTEE 2464 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXX 599 IL D+YA+VLG ERVG+DDSFFDLGGDS+ +M+++A AA R +F T Sbjct: 2465 ILTDIYARVLGHERVGIDDSFFDLGGDSLSAMRLLAGINAALNTGVTVRTLFDAPTVAQL 2524 Query: 600 XXXXXXXXESHVVDEGVGPVVA------TPI------MRWLREVDGPTGQFNQTVITQAP 647 + V P+ A P+ + +L ++ GP+ +N T + Sbjct: 2525 CTRISRD------ETRVAPLTARERPARVPLSFAQSRLWFLDQLQGPSAIYNMTAAFRID 2578 Query: 648 AGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR----TVD 703 + D + ++ RH +LR E D +++P GA E + +V Sbjct: 2579 GELDADALAAAFTDVVARHESLRTLFE--APDGVPHQMVMPAGGAEPGWEVIDAGDWSVG 2636 Query: 704 ALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIA 760 L + + +R+ D +A + A R T LV+++HH+A DG S L+ DL A Sbjct: 2637 QLREAIDEISRHAFDLSAEIPLKAALFRVTDNEHALVVVVHHIAADGWSIAPLMADLGTA 2696 Query: 761 WAQHCTGQS---IELPAGGTSFARWS-ALLAEHAKTDT--VRDLADAWRAVTSVPQALPP 814 +A C G++ +LP ++ W A E +D+ R L A+ +P+ + Sbjct: 2697 YASRCAGEAPAWADLPVQYADYSLWQRAQFGELQDSDSPIARQLRYWHGALAGLPERI-T 2755 Query: 815 VQPDTDTYVTAGQLSASL----DVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNR 870 + D + A Q A++ VE RQ + E+ A A ++ A + + Sbjct: 2756 LPTDRPYPLAADQRGATIAVNWPVELQRQ-IAELAAENNATSFMVVQAALLILLSRLSAN 2814 Query: 871 SDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 SD +G + G D L + VG+F Sbjct: 2815 SDVAVGFPIAGR-------RDPALDQLVGFF 2838 Score = 730 bits (1885), Expect = 0.0 Identities = 465/1042 (44%), Positives = 595/1042 (57%), Gaps = 71/1042 (6%) Query: 1116 VYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLT----ADPMIAW 1171 +Y + I G LD L A VVARH +L F G P Q++ A+P W Sbjct: 2568 IYNMTAAFRIDGELDADALAAAFTDVVARHESLRTLFEAPDGVPHQMVMPAGGAEP--GW 2625 Query: 1172 RYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVID 1231 +D D + E + R A DL +AAL R + N+H V+ HHI D Sbjct: 2626 EVID--AGDWSVGQLREAIDEISRHAF-DLSAEIPLKAALFRVTDNEHALVVVVHHIAAD 2682 Query: 1232 GWSLPILLQEIFAGYFGHRLPAAAP--------YRNFVNWLXXXXXXXXXXX-------- 1275 GWS+ L+ ++ Y R AP Y ++ W Sbjct: 2683 GWSIAPLMADLGTAY-ASRCAGEAPAWADLPVQYADYSLWQRAQFGELQDSDSPIARQLR 2741 Query: 1276 -WREVLDGFETPTLVAPPGVPGPRGIESYRVS------AETTRALGELARSQHTTINTVL 1328 W L G + P P P + + E R + ELA + T V+ Sbjct: 2742 YWHGALAGLPE-RITLPTDRPYPLAADQRGATIAVNWPVELQRQIAELAAENNATSFMVV 2800 Query: 1329 QAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAKVSADTTVGD 1386 QAA LL R++ DVA G ++GR PA + +VG +NT+ +RA ++ + T+ + Sbjct: 2801 QAALLILLSRLSANSDVAVGFPIAGRRDPA----LDQLVGFFVNTLVLRADLAGNPTICE 2856 Query: 1387 LLRQ-----LQSHHNDTLEHEHLA--LNDIHHVSGHEQLFDTLFLYESYP----IDTSAF 1435 +L Q L++ N + E L LN + ++ H + ++++ D++A Sbjct: 2857 VLEQVRVRSLEAFDNQDVPFEVLVDRLNPVRSLA-HHPVVQVALAWQNFAGRHVNDSAAG 2915 Query: 1436 MGVQELAVTEFN------NREYNHYPLSVMALPGHELGL--RVEYDTSVFDVSEIETLID 1487 + + +L +++ + N G G+ VE+ T VFD I++L+ Sbjct: 2916 VELGDLRISQMPVETRTARMDVNFSLAERWTKSGEPAGIGGTVEFRTDVFDARTIQSLVT 2975 Query: 1488 RFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVER 1547 R QR+L A+ +PA RLS +D++DDDER +L N A L + P S+ +FA +V R Sbjct: 2976 RLQRVLTAITANPAARLSVVDLLDDDERCRLSVLGNHATLARTPSRPASVTGLFAEKVSR 3035 Query: 1548 DPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLK 1607 PEA AV+ S Y ELD AAN+LA+LL GA PG+ VAL+ RSA+AI AIL +LK Sbjct: 3036 TPEAVAVSCGERSWTYRELDSAANRLAHLLIDQGAGPGQVVALLSNRSAEAIAAILGILK 3095 Query: 1608 TGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYP-- 1665 TGAAYLPIDP+VP ARL F+L DA PV AVTT DL R DG L ++++ V +P Sbjct: 3096 TGAAYLPIDPAVPDARLTFVLADAGPVVAVTTTDLADRLDGRGLAIIDI--RGVGPHPPD 3153 Query: 1666 ---STTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQW 1722 + P PD AY+IYTSGTTGVPKGVA++H NVTQ+LD+L A LP PG VWS Sbjct: 3154 AGFDGAIPDPEPDHTAYLIYTSGTTGVPKGVALSHRNVTQLLDSLDAGLP-HPG-VWSHS 3211 Query: 1723 HSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSP 1782 HSL FDVSVWEI+GALL GGR+VI E SP+DLHALL+ E V V+ QTPSA R + Sbjct: 3212 HSLAFDVSVWEIFGALLSGGRVVIASEGATSSPEDLHALLIREHVTVITQTPSAARALPR 3271 Query: 1783 EGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSP 1842 EGL+ ALVV GEACP EVVD+WA RVMINAYGPTE+T+ AISAPL+ G VPIG+P Sbjct: 3272 EGLDSAALVVVGEACPAEVVDQWAPGRVMINAYGPTETTMCVAISAPLTAGQG-VPIGTP 3330 Query: 1843 VPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYR 1902 V A FVLDE LR VP GVVGELY+A LT TRFVACPFG+PG RMYR Sbjct: 3331 VTGAALFVLDESLRQVPVGVVGELYVAGRGVGYGYVGRAPLTSTRFVACPFGDPGTRMYR 3390 Query: 1903 TGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDK 1962 TGDLV W DGQL YLGRADEQVKIRG+RIEL EIQA L+ + GV++AVVIAREDRPGDK Sbjct: 3391 TGDLVCWRPDGQLNYLGRADEQVKIRGHRIELAEIQAVLASLGGVEEAVVIAREDRPGDK 3450 Query: 1963 RLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQ 2022 RLVGYITGTAD R + +RLPAYMVPAAVV L+ +PLTVNGKLD RALPAP+Y Sbjct: 3451 RLVGYITGTADCGGLRMAIADRLPAYMVPAAVVRLDAIPLTVNGKLDTRALPAPDYGDHG 3510 Query: 2023 RYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVR 2082 RYRAP E+ LA I+A VLG+ER +M+V + A R Sbjct: 3511 RYRAPANAVEEVLADIYAQVLGLERVSVDDSFFDLGGDSILSMQVVSR-GRAAGLLCRPR 3569 Query: 2083 TLFEAPTVAKLSLHVEHDAGER 2104 +F TVA+L+ V+ AG R Sbjct: 3570 DIFVEQTVARLARVVQVTAGSR 3591 Score = 714 bits (1843), Expect = 0.0 Identities = 437/969 (45%), Positives = 563/969 (58%), Gaps = 65/969 (6%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P R L + +LDE E D+++ WGN+ VLT P +IP LFA QV R+P ++AL Sbjct: 4479 MVADPR-RPLSAVQILDETERDRLQRWGNQGVLTHLAQ-PASIPELFARQVTRSPKSIAL 4536 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V DRS TY LDEASNRLA L G PG VA + PRS EA+++IL+VLKTGAAYLP Sbjct: 4537 VCEDRSLTYLALDEASNRLARFLIGRGVGPGERVALMFPRSAEAVVAILAVLKTGAAYLP 4596 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P AR+ FM+SDA P+A +TTA L R + L V+D+ DPAI L+ P Sbjct: 4597 IDPALPGARVEFMVSDAGPMAVVTTAALAERFSGFGLPVVDVQDPAIAAECGAGLTMPSA 4656 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D +A++ YTSGTTG+PK VAVT NVTQL +L +P PGQVW+Q+HS FD SVWEI Sbjct: 4657 DGMAHIIYTSGTTGLPKGVAVTQRNVTQLFDSLQIGVPLEPGQVWTQFHSYSFDFSVWEI 4716 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPE++ S D H LL+ E+V+VL QTPSA ML +GL+ TL++ Sbjct: 4717 WGALLHGGRLVVVPETIARSSRDFHRLLVREQVTVLTQTPSAVSMLPVDGLDVATLVIGA 4776 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 E C ELVDRWAPGR M+N YGPTE T++ S PL FVLD+W Sbjct: 4777 EPCSPELVDRWAPGRTMVNVYGPTETTMWLCASAPLAPGLGAPPIGSPTAWAAFFVLDEW 4836 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELY+ G GV GY R LTA+RF+ACPFGE G RMYRTGDLVRW +DGQ Sbjct: 4837 LRPVPAGVVGELYLGGAGVGIGYWRRSGLTAARFMACPFGEPGSRMYRTGDLVRWRADGQ 4896 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L+YLGRADEQVKIRGYRIELGEIQ+ALA LDGV+ A VIAREDRPGDKRLVGYITG ADP Sbjct: 4897 LDYLGRADEQVKIRGYRIELGEIQSALAALDGVENAAVIAREDRPGDKRLVGYITGAADP 4956 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 RTALAE LP YMVP AVV L +P+TVNGKLD RALPAP+Y+ + YRAP ++ Sbjct: 4957 VGARTALAERLPGYMVPAAVVGLAALPMTVNGKLDVRALPAPDYQDV-DRYRAPVGAVQE 5015 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXX 599 ILA +YA+VL VERVGVDDSFFDLGGDS+ +M++VA AA R +F T Sbjct: 5016 ILAGIYARVLDVERVGVDDSFFDLGGDSVSTMRLVAAVNAALNADLSTRTVFDAPTIAQL 5075 Query: 600 XXXXXXXX---ESHVVDEG--VGPVVATPIMRW-LREVDGPTGQFNQTVITQAPAGVTED 653 E VV E V P+ W + ++ GP+ +N V + + Sbjct: 5076 ALRIGEGAGGPEPLVVVERPEVIPLSFAQNRLWFVDQLQGPSPVYNMPVGLRLYGRLDAA 5135 Query: 654 DVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEA 713 + L L+ RH +LR R + + + +++P+ E + T Sbjct: 5136 ALGAALSDLIGRHESLRTRFDAPGGNPRQ--IVLPDGPIDFGWEIIDATSWQT------- 5186 Query: 714 RNRLDPAAGAMVSAVW---------------VRETSQLVLMIHHLAVDGVSWRILLEDLN 758 +LD A A V + E LV ++HH+A DG S L+ DL+ Sbjct: 5187 -GQLDEAIAATVCRSFDLAIEIPLYARVFRIAEEEHVLVAVVHHIAADGWSLTPLMHDLS 5245 Query: 759 IAWAQHCTGQSIE---LPAGGTSFARWS-ALLAEHAKTDT--VRDLADAWRAVTSVPQ-- 810 +A+A C G + + LP + W A L + D+ LA A+ +P+ Sbjct: 5246 VAYASRCRGHAPDWAPLPVQYVDYTLWQRAQLGDLGDGDSPISAQLAYWEGALAGLPERV 5305 Query: 811 ALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRA-GVQDILLVAFGLA--WTEF 867 ALP +P A Q ++++V+ +L +V A R G +++ LA Sbjct: 5306 ALPTDRPYPP---VADQRGSTVEVQWPPELQQQVRATAREHGATSFMVMQASLAVLLASI 5362 Query: 868 LNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALG 927 SD +G + G D L + VG+F V NL ++GD + Sbjct: 5363 SGTSDVAVGFPIAGR-------RDTALDQLVGFF---------VNNLVLRVDLSGDPTVA 5406 Query: 928 GIVKAVKEQ 936 ++ V+++ Sbjct: 5407 ELLTQVRQR 5415 Score = 707 bits (1826), Expect = 0.0 Identities = 426/948 (44%), Positives = 553/948 (58%), Gaps = 53/948 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+PS R L S D+LDE EH +++ WGNR +L P ++PALFAEQ R P AVA+ Sbjct: 5534 MTADPSRR-LSSIDVLDEAEHTRVDRWGNRELLNRPPAVRRSVPALFAEQAARVPHAVAI 5592 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 R TYRE+D+AS++LAH L G +PG +VA L R EA++++L+VLKTGAAYLP Sbjct: 5593 SFNGRELTYREVDQASDQLAHRLIAQGVRPGESVALLTERCPEAVVAMLAVLKTGAAYLP 5652 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPA--IDRRPSDALSGP 178 +DPA PD R+ FM+ DA P AA+TTADL RL Y L VID+ D A +L P Sbjct: 5653 IDPALPDVRVEFMIGDAAPTAAITTADLTDRLAGYALTVIDVGDIAEGASSGAGSSLPLP 5712 Query: 179 RPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVW 238 PDD+AY+ YTSGTTGVPK VA+ HHNVT L+ + L G W+QWHS FD SV Sbjct: 5713 SPDDIAYIIYTSGTTGVPKGVAIAHHNVTALMGSPATFLA---GHTWAQWHSYAFDASVE 5769 Query: 239 EIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIV 298 EIWG+LLHGGRLVVVPES SP+ L LL+ E+V+ L QTPSA +L+PE L++ +L+V Sbjct: 5770 EIWGSLLHGGRLVVVPESAAHSPEHLTALLVAEQVTALSQTPSAVALLTPESLDAVSLLV 5829 Query: 299 AGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLD 358 AGE CP E+VDRWAPGR+M+NAYGPTE TI A+ + L +FVLD Sbjct: 5830 AGEPCPGEVVDRWAPGRLMVNAYGPTETTICASRTAALVGGTGSPSIGAPVPGAAMFVLD 5889 Query: 359 KWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGET---GERMYRTGDLVRW 415 LRP P GVVGELY+AGHGV GY GR LTASRFVACPF + G+RMYRTGDLVRW Sbjct: 5890 GLLRPVPPGVVGELYIAGHGVGVGYAGRTGLTASRFVACPFADAQLPGQRMYRTGDLVRW 5949 Query: 416 GSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT 475 +DGQLEYLGRADEQVKIRGYRIEL EI + L LDGVDQA VIAREDRPGD+RLVGY+T Sbjct: 5950 RADGQLEYLGRADEQVKIRGYRIELAEIHSVLTALDGVDQAAVIAREDRPGDRRLVGYVT 6009 Query: 476 GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPS 535 GTA+PA+LR LAE LPAYMVP AVVVL +P+TVNGKLD RALP PEY+ + YRAP Sbjct: 6010 GTANPAKLRAQLAEQLPAYMVPVAVVVLAALPMTVNGKLDTRALPRPEYQDI-DRYRAPG 6068 Query: 536 TPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGIQCRPRDIFVEQ 594 T E+ILA +YA+VLGVERVGVDDSFFDLGGDS+ +M+++A A R +F Sbjct: 6069 TLTEEILAGIYARVLGVERVGVDDSFFDLGGDSLSAMRLIAAVNADLNAVVSVRTVFEAP 6128 Query: 595 TXXXXXXXXXXXXESHVVDEGVGPVVAT------PI------MRWLREVDGPTGQFNQTV 642 T S + P+VA P+ + +L ++ GP+ +N Sbjct: 6129 TVGQLAPRIADASSS------LSPLVAAERPAQIPLSFAQARLWFLDQLQGPSPVYNMAT 6182 Query: 643 ITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR-- 700 + + D + L ++ RH +LR + T + ++VP A A + + Sbjct: 6183 ALRISGALDVDALGAGLADVVARHESLRTQFRATGGVPQQ--VVVPAADAHFGWDVVDAT 6240 Query: 701 --TVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLE 755 T L + + AR+ D + + A R T L ++HH+A D S L+ Sbjct: 6241 GWTTSQLREAIGEAARHTFDLSNEIPLYARLFRITGDEYVLAAVVHHIAADAWSITPLVT 6300 Query: 756 DLNIAWAQHCTGQS---IELPAGGTSFARWS-ALLAEHAKTDT-VRDLADAWR-AVTSVP 809 DL +A+ G + L + W A + A + + D W+ A+ +P Sbjct: 6301 DLGVAYVSRRAGHAPGWAPLAVQYVDYTLWQRAEFGDFADGGSRIAAQLDYWQDALAGMP 6360 Query: 810 Q--ALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEF 867 + LP +P T G A ++ + V A +L A G+ ++ Sbjct: 6361 ERVELPTDRPYPSTADQRGSTMAVQWPAALQEQIARVAREHNATSFMVLQAALGVLLSKL 6420 Query: 868 LNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLP 915 +D +G + G D L +G+F + L + P Sbjct: 6421 SGNTDVAVGFPIAGR-------RDPALDELIGFFVNTLVLRLDLSGDP 6461 Score = 668 bits (1723), Expect = 0.0 Identities = 433/1010 (42%), Positives = 558/1010 (55%), Gaps = 55/1010 (5%) Query: 1125 ITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD 1184 I G+++ L AV V+ L A F E G+ Q + P + DL G P Sbjct: 38 IEGIIEHGLLEQAVRQVIHEAEPLRAVFSELNGQVFQTVVDYPDTELAHHDLTGSP-DPV 96 Query: 1185 HEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFA 1244 + ++ + + A L + P FR AL++ + F + HHIV DG + +L I A Sbjct: 97 GDAYRIAGSIQKAPMPL-DGPLFRFALMQVRPDDFYFFVCCHHIVTDGIGMGLLCHRIAA 155 Query: 1245 GYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPP------GVPGPR 1298 Y A P F + + LD P G P Sbjct: 156 VYSAIATDAPVPAPIFGSLRSLVESESDYEGSEDYLDDAAYWASCGPLDDELRYGTPPAA 215 Query: 1299 G--IESYRVSAE------TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTA 1350 + Y SA EL+ + V+ AA L+ G +V Sbjct: 216 AARLAEYEPSAPIQLDPAVVAKARELSHALGVRRAAVITAACALLVHGEVGGAEVVLDFP 275 Query: 1351 VSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIH 1410 VS R A + G+ VP+R S T+V D + + + L H+ L DI Sbjct: 276 VSRRVRP--EALLVPGMSSGVVPLRLTTSPYTSVADFCEHVATRIQEALRHQRFPLRDIE 333 Query: 1411 HVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEF----NNREYNHYPLS-----VMAL 1461 +G ++ +P +A + + +F + H L V Sbjct: 334 SKTGFQR--------GGWPSRHAAVNFIPTTRLADFAGAAGSGTVTHTGLVDQFGLVFIK 385 Query: 1462 PGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEW 1521 EL L +F + TL DRF+R+L M DP R LS++DV + + QLD W Sbjct: 386 NDDELFLSTTGVGELFPDCDARTLADRFERVLSEMTADPRRPLSAIDVRAEAQCPQLDLW 445 Query: 1522 ANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYG 1581 +NR LT PV P SIPE+FA QV RDP A AV+ G S++Y LDEA+N+LA+LL +G Sbjct: 446 SNRGALTHPVPRPLSIPELFAEQVVRDPGAVAVSCGGRSVSYRGLDEASNRLAHLLISHG 505 Query: 1582 AAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGD 1641 PG+ VAL++ RS +A+VAI+ VLKTGAAY+PIDPSVP ARL F+L DA PV VTT + Sbjct: 506 VGPGQRVALLLSRSVEAVVAIMGVLKTGAAYVPIDPSVPDARLRFVLCDAGPVVVVTTAE 565 Query: 1642 LRSRFDGFDLQVVEVDDPAVEIYPSTTL-LTPSPDDIAYMIYTSGTTGVPKGVAITHGNV 1700 L R G L VV++D AV PS L + P PDD+AY+IYTSGTTG PKGVAI H NV Sbjct: 566 LADRLAGHGLTVVDIDGRAVYGQPSAALSIMPHPDDVAYLIYTSGTTGTPKGVAIPHHNV 625 Query: 1701 TQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHA 1760 T++L+ + A+L PG W+Q HSL FD SVWEI+GALLHGGRLV+VPE + +P++LHA Sbjct: 626 TRLLEAIDADLELVPGQGWAQCHSLAFDFSVWEIFGALLHGGRLVVVPEGVTRAPEELHA 685 Query: 1761 LLVSEGVNVLYQTPS------AVRMMSPE--GLEGTALVVAGEACPTEVVDRWAVDRV-- 1810 LLV E V+VL QTPS AV SPE L + +V GEA + W D Sbjct: 686 LLVHERVSVLSQTPSAFYALHAVDTASPEQRQLALSVVVFGGEALEPARLSDWFQDHPQS 745 Query: 1811 --MINAYGPTESTIYAAISAPLSPGSDVV----PIGSPVPKGATFVLDEWLRPVPPGVVG 1864 +IN YG TE+T++A+ SDVV PIG+P+ + FVLD+WLRP+ G VG Sbjct: 746 PRLINMYGITETTVHASFRE--ITVSDVVGTSSPIGAPLADLSFFVLDDWLRPLQAGAVG 803 Query: 1865 ELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQ 1924 ELY+A LT TRFVACPFG G RMYRTGDLV WG DGQL+YLGRADEQ Sbjct: 804 ELYVAGAGVGYGYAGRTSLTATRFVACPFGGRGTRMYRTGDLVCWGSDGQLRYLGRADEQ 863 Query: 1925 VKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNR 1984 VKIRGYRIELGE+Q+AL+ ++GVDQ VIAREDRPGDKRLVGY TG+ADP R LT+R Sbjct: 864 VKIRGYRIELGEVQSALAALEGVDQVAVIAREDRPGDKRLVGYFTGSADPGELRETLTDR 923 Query: 1985 LPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLG 2044 LP+YMVPAA+V LE+LPLTVNGKLDR ALPAPEY++ +RYR P T E+TLA I+A VLG Sbjct: 924 LPSYMVPAAIVVLESLPLTVNGKLDRNALPAPEYRAVERYRRPATVVEETLAAIYAQVLG 983 Query: 2045 VERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +ER AM+V++AV A R +F TVA+L+ Sbjct: 984 LERVGADDSFFELGGDSILAMQVSSAVRMA-GLACRPRDIFVQQTVARLA 1032 >tr|B2HJA1|B2HJA1_MYCMM Tax_Id=216594 SubName: Full=Non-ribosomal peptide synthetase;[Mycobacterium marinum] Length = 3889 Score = 2333 bits (6046), Expect = 0.0 Identities = 1236/2131 (58%), Positives = 1494/2131 (70%), Gaps = 40/2131 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P R L S DLLD EH +++V GNRAVL +P PV++P LFA QV + AL Sbjct: 1504 MVADPDRR-LSSVDLLDAAEHARLDVVGNRAVLAEPLVEPVSVPGLFAAQVASRAEVTAL 1562 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V DRS TYRELD A+NRLAH+L + G PG V L+ RS EA+++IL+VLK+GAAYL Sbjct: 1563 VCEDRSLTYRELDRAANRLAHLLVDQGVGPGDVVGLLLERSVEAVIAILAVLKSGAAYLA 1622 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDR-RPSDALSGPR 179 +D HPD RIGFM+ DA PVA +TTA L RL Y +AVID+ DPAI P L P Sbjct: 1623 IDVNHPDGRIGFMIEDAAPVAVITTAGLAQRLAGYPVAVIDIDDPAIATCYPGHGLPFPS 1682 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHAD-LPSGPGQVWSQWHSLVFDVSVW 238 D++AY+ YTSGTTG PK V +THHN+TQL +++ A PGQ+W+Q HS FD SVW Sbjct: 1683 ADNIAYLIYTSGTTGKPKGVGITHHNITQLFTSVAATGFTPAPGQIWTQCHSYAFDYSVW 1742 Query: 239 EIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTL-- 296 E+WGALLHGGRLVVVPE V S +L LL+TE V VL QTPSA L E L Sbjct: 1743 EMWGALLHGGRLVVVPELVTRSAAELLALLVTEGVGVLSQTPSAFYALQAEDAAQPQLGR 1802 Query: 297 -------IVAGEACPTELVDRWAPGRV----MINAYGPTEATIYAAMSEPLXXXXXXXXX 345 + GEA + W +IN YG TE T++A+ E + Sbjct: 1803 QLCLDAVVFGGEALEPARLGPWLANHGRRPRLINMYGITETTVHASFREIVRHDLGFAVS 1862 Query: 346 XXXXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETG 403 L FVLD WLRP P GV GELYVAG GV GY R LTASRFVACPFG G Sbjct: 1863 PVGVPLANLAFFVLDGWLRPVPVGVAGELYVAGAGVGCGYWRRSGLTASRFVACPFGALG 1922 Query: 404 ERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIARED 463 RMYRTGD+VRWG DGQL+Y+GRADEQVKIRGYRIELGE+ AAL++LDGVDQAVVIARED Sbjct: 1923 ARMYRTGDVVRWGPDGQLQYVGRADEQVKIRGYRIELGEVAAALSQLDGVDQAVVIARED 1982 Query: 464 RPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPE 523 RPGDKRLVGY+ G+ D Q R ALA++LPAYMVP AVVV+D++PLTVNGKLD RALPAP+ Sbjct: 1983 RPGDKRLVGYLVGSVDAGQARAALAQALPAYMVPAAVVVVDSLPLTVNGKLDIRALPAPQ 2042 Query: 524 YRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGI 583 Y A YRAP++P E++LA +YAQVLG++RV VD SFFDLGGDSIL++QVVARARAAG+ Sbjct: 2043 Y-GATGSYRAPASPVEEVLAGIYAQVLGLDRVAVDQSFFDLGGDSILAIQVVARARAAGV 2101 Query: 584 QCRPRDIFVEQTXXXXXXXXXXXXESHV----VDEGVGPVVATPIMRWLREVDGPTGQFN 639 CRPRD+F EQT +++ ++ VG VVATPIM WL+ +DGP +FN Sbjct: 2102 VCRPRDVFTEQTVAGLATVAAVFDDANDDGGHAEDSVGEVVATPIMLWLQSLDGPLKEFN 2161 Query: 640 QTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECL 699 QT + QAPA ++ DV+V LQA+LDRHA LRL+V+ + T W L VP G V AR+C+ Sbjct: 2162 QTALLQAPAAMSYGDVIVSLQAVLDRHAMLRLQVDT--DATGRWLLHVPAPGCVDARKCV 2219 Query: 700 RTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNI 759 R V AL+DD LV+AR+RLDP+AG MVSA+WV ++QL L+IHHLA+DGVSWRILL+DLN Sbjct: 2220 RAVTALSDDELVQARSRLDPSAGVMVSALWVTSSAQLALVIHHLAIDGVSWRILLDDLNS 2279 Query: 760 AWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDT 819 W QH +G+ LPAGGTSF RW+ALLAE A + T D A AWR V + P LP V+P Sbjct: 2280 VWEQHRSGEMAALPAGGTSFRRWAALLAEQAYSATAVDHAAAWRQVLATPSVLPAVKPAV 2339 Query: 820 DTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDV 879 DTY TA +L SLD+ETTR LL PAAF AGVQDILL+AF LAW+EF + + I +DV Sbjct: 2340 DTYATAQRLLVSLDIETTRTLLAAAPAAFHAGVQDILLIAFALAWSEFSSGGGSRIAIDV 2399 Query: 880 EGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRS 939 EGHGR++ELA VDLS T+GWFTTKYPVA++V L W QVVAGDAALG +VK KEQLR Sbjct: 2400 EGHGRHEELAFGVDLSHTLGWFTTKYPVAVSVGALRWAQVVAGDAALGAVVKDAKEQLRG 2459 Query: 940 LPEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXX 999 LP+GL YGL+RYLN EV+L G++PTIGFNYLGRL ++ W+I + Sbjct: 2460 LPDGLLYGLIRYLNREVELAGAEPTIGFNYLGRLSTRT-TAGDDHWQIARWGSLFTDECA 2518 Query: 1000 XVPMP--LMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAH 1057 +P L HTVEL+A T DT+ GP L A WTWA SA D Q R+SRLWFEAL GICAH Sbjct: 2519 SAELPIQLFHTVELDAVTFDTEAGPQLHAQWTWATSALDRAQLNRISRLWFEALTGICAH 2578 Query: 1058 VRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVY 1117 VR GGGG+TPSD+ RL+Q QID+L QRY V DVLPLTP+QQGLLFH+ ARG G D+Y Sbjct: 2579 VRAGGGGMTPSDIGLTRLSQHQIDQLEQRYCVADVLPLTPLQQGLLFHADAARG-GADLY 2637 Query: 1118 AVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFV--EQFGEPVQVLTADPMIAWRYL- 1174 VQ DIT++G LD RLR A V+ RHPNLAA+FV E EPVQ++ D ++ WR + Sbjct: 2638 VVQFDITLSGALDPRRLRTAAQEVLRRHPNLAAQFVWGEPLDEPVQIILNDLVLEWRTVE 2697 Query: 1175 -DLRGD-DLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDG 1232 D GD D + I+++CA ER AV DL FR ALIRT+ +HR VLT HHIV DG Sbjct: 2698 FDPAGDPDAHVEQHIDEVCADERVAVADLGGGSPFRIALIRTAPCEHRLVLTAHHIVCDG 2757 Query: 1233 WSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPP 1292 WS+PI++QEI A Y G L A YRNF+ WL WRE+ F PTLV P Sbjct: 2758 WSMPIVMQEILAAYAGQPLAAPGSYRNFLTWLAERDKSAARTAWRELFADFRHPTLVGLP 2817 Query: 1293 ---GVPGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGT 1349 G+ G RG+ESY + T AL ELARS T+N VLQAA+ QLL +TGQ DVAFGT Sbjct: 2818 DHLGL-GSRGVESYLLPIGITEALTELARSCRVTVNIVLQAAFAQLLSWLTGQHDVAFGT 2876 Query: 1350 AVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI 1409 VSGRPA++AG SMVGL INTVP RA++++ TT +LL QLQS H +TLEH HLAL+DI Sbjct: 2877 TVSGRPAEVAGVHSMVGLFINTVPTRARMASTTTTRELLDQLQSVHYETLEHHHLALSDI 2936 Query: 1410 HHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLR 1469 H VSGH+QLFDTLF+YE+YPID +A G ELA++ REY+HYPL V A+PG +LGLR Sbjct: 2937 HRVSGHDQLFDTLFVYENYPIDKTAAQGTGELAISGIGCREYSHYPLVVQAMPGDQLGLR 2996 Query: 1470 VEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQ 1529 VE+ T VFD + I LI R QR++ AM+ DP RRLSS+D++D E +LD NRAVL + Sbjct: 2997 VEFRTDVFDAASIAALIQRLQRVVVAMVADPDRRLSSVDLLDAAEHARLDVVGNRAVLAE 3056 Query: 1530 PVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVA 1589 P+ P S+P +FA QV E A+ SL Y ELD AAN+LA+LL G PG V Sbjct: 3057 PLVEPVSVPGLFAAQVASRAEVTALVCGDRSLTYRELDRAANRLAHLLVDQGVGPGDVVG 3116 Query: 1590 LMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGF 1649 L++ RS +A++AILAVLK+GAAYL ID + P R+ FM+ DA PVA +TT L R G+ Sbjct: 3117 LLLERSVEAVIAILAVLKSGAAYLAIDVNHPDGRIGFMIEDAAPVAVITTAGLAQRLAGY 3176 Query: 1650 DLQVVEVDDPAVEI-YPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLP 1708 + V+++DDPA+ YP L PS D+IAY+IYTSGTTG PKGV ITH N+TQ+ ++ Sbjct: 3177 PVAVIDIDDPAIATCYPGHGLPFPSADNIAYLIYTSGTTGKPKGVGITHHNITQLFTSVA 3236 Query: 1709 AE-LPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 A PG +W+Q HS FD+SV+E+WGALLHGGRLV+VPES+ GSP DLHALLV+E V Sbjct: 3237 ATGFTPAPGQIWTQCHSYAFDLSVFEMWGALLHGGRLVVVPESVTGSPADLHALLVAEQV 3296 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAIS 1827 +VL QTPSAV M+S +GLE T LVV GEACP EVVD WA R+M+N YGP+E+T+Y ++S Sbjct: 3297 DVLAQTPSAVAMLSTQGLESTTLVVGGEACPAEVVDNWAPGRMMVNQYGPSETTMYVSMS 3356 Query: 1828 APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTR 1887 APL PGS PIG PVP+ A FVLD WLRPVP GV GELY+A LT +R Sbjct: 3357 APLVPGSGPAPIGVPVPRAALFVLDGWLRPVPAGVAGELYVAGAGVGCGYWRRSGLTASR 3416 Query: 1888 FVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGV 1947 FVACPFG GARMYRTGD+VRWG DGQLQY+GRADEQVKIRGYRIELGE+ AALS +DGV Sbjct: 3417 FVACPFGALGARMYRTGDVVRWGPDGQLQYVGRADEQVKIRGYRIELGEVAAALSQLDGV 3476 Query: 1948 DQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGK 2007 DQAVVIAREDRPGDKRLVGY+ G+ D AR+ L LPAYMVPAAVV +++LPLTVNGK Sbjct: 3477 DQAVVIAREDRPGDKRLVGYLVGSVDAGQARAALAQALPAYMVPAAVVVVDSLPLTVNGK 3536 Query: 2008 LDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRV 2067 LD RALPAP+Y + YRAP + E+ LAGI+A VLG++R AMRV Sbjct: 3537 LDIRALPAPQYGATGSYRAPASPVEEVLAGIYAQVLGLDRVAVDQSFFDLGGNSILAMRV 3596 Query: 2068 TAAVNTALDADLSVRTLFEAPTVAKLSLHVE 2098 ++A+ L DL VR +FEAPTV LS VE Sbjct: 3597 SSAIEKFLGVDLPVRLMFEAPTVESLSRQVE 3627 Score = 794 bits (2050), Expect = 0.0 Identities = 475/1067 (44%), Positives = 628/1067 (58%), Gaps = 54/1067 (5%) Query: 1088 DVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPN 1147 D+ DV+ L+P+Q GL + + DD Y V L I + G LD LR ++ RHPN Sbjct: 10 DIEDVMTLSPLQLGLFALAMASGAASDDPYTVALGIDVHGSLDVGLLRSCALAMLKRHPN 69 Query: 1148 LAARFVEQ-FGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPT 1206 L ARF+ + PVQV+ ++ + W ++ + L A ER+ DL P Sbjct: 70 LRARFLGRGLPHPVQVVPSEVQLEWARVEATAETAGA------LEAQERNRGFDLEMGPA 123 Query: 1207 FRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH----RLPAAA-PYRNFV 1261 R LI G++ RF++T HHIVI GWS+ + + E+ Y LPA PYR+++ Sbjct: 124 IRFLLIELPGDRWRFLITAHHIVIGGWSIALFVDELLTLYEADCNIDTLPAQPRPYRDYI 183 Query: 1262 NWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIE--------SYRVSAETTRAL 1313 WL WRE L G PTL+A P G G++ + T +L Sbjct: 184 GWLERCDVEQGQRQWREHLAGLAAPTLLAAP--LGSSGVQPDSLPKRAELTLDEGATTSL 241 Query: 1314 GELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVP 1373 + ARS+ T+NT+ Q AW +L +T +RDV FG VS RPA+LA ESMVGL +NTVP Sbjct: 242 VDGARSRGVTVNTLTQLAWALMLSMLTDRRDVVFGVTVSSRPAELARVESMVGLFVNTVP 301 Query: 1374 IRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTS 1433 +R ++ TTV +Q EH +L+ + I ++G +LFDTL +++++P Sbjct: 302 LRVRLDPKTTVAQQCALIQRDAARLREHAYLSHSQIRALAGMGELFDTLLVFQNFPSLGL 361 Query: 1434 AFMGVQELAVTEFNN---REYNHYPLSVMA-LPGHELGLRVEYDTSVF-DVSEI---ETL 1485 A + + F++ + H+P+ + A L L L + + + F D++E + L Sbjct: 362 ADGKARAVGAARFDSLTVQSPTHFPVCITAELTDARLSLSIATNANAFGDITESALGDRL 421 Query: 1486 IDRFQRLLEAMIDDPARRLSSM--DVVDDD----ERTQLDEWANRAVLTQPVDSPQSIPE 1539 + QRLL M D P R +S + D D E +LD NRAVL +P+ P S+P Sbjct: 422 VAVLQRLLP-MWDRPLRDVSMLLDGQTDGDTAVSEHARLDVVGNRAVLAEPLVEPVSVPG 480 Query: 1540 VFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAI 1599 +FA QV E A+ SL Y ELD AAN+LA+LL G PG V L++ RS +A+ Sbjct: 481 LFAAQVASRAEVTALVCGDRSLTYRELDRAANRLAHLLVDQGVGPGDVVGLLLERSVEAV 540 Query: 1600 VAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDP 1659 +AILAVLK+GAAYL ID + P R+ FM+ DA PVA +TT L R G+ + V+++DDP Sbjct: 541 IAILAVLKSGAAYLAIDVNHPDGRIGFMIEDAAPVAVITTAGLAQRLAGYPVAVIDIDDP 600 Query: 1660 AVEI-YPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAE-LPAGPGA 1717 A+ YP L PS D+IAY+IYTSGTTG PKGV ITH N+TQ+ ++ A PG Sbjct: 601 AIATCYPGYGLPFPSADNIAYLIYTSGTTGKPKGVGITHHNITQLFTSVAATGFTPAPGQ 660 Query: 1718 VWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAV 1777 +W+Q HS FD SVWE+WGALLHGGRLV+VPE + S +L ALLV+EGV VL QTPSA Sbjct: 661 IWTQCHSYAFDYSVWEMWGALLHGGRLVVVPELVTRSAAELLALLVTEGVGVLSQTPSAF 720 Query: 1778 RMMSPEGLEGT---------ALVVAGEACPTEVVDRWAVDRV----MINAYGPTESTIYA 1824 + E A+V GEA + W + +IN YG TE+T++A Sbjct: 721 YALQAEDAAQPQLGRQLCLDAVVFGGEALEPARLGPWLANHGRRPRLINMYGITETTVHA 780 Query: 1825 AISAPLSP--GSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXX 1882 + + G V P+G P+ A FVLD WLRPVP GV GELY+A Sbjct: 781 SFREIVRHDLGFAVSPVGVPLANLAFFVLDGWLRPVPVGVAGELYVAGAGVGCGYWRRSG 840 Query: 1883 LTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALS 1942 LT +RFVACPFG GARMYRTGD+VRWG DGQLQY+GRADEQVKIRGYRIELGE+ AALS Sbjct: 841 LTASRFVACPFGALGARMYRTGDVVRWGPDGQLQYVGRADEQVKIRGYRIELGEVAAALS 900 Query: 1943 DVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPL 2002 +DGVDQAVVIAREDRPGDKRLVGY+ G+ D AR+ L LPAYMVPAAVV +++LPL Sbjct: 901 QLDGVDQAVVIAREDRPGDKRLVGYLVGSVDAGQARAALAQALPAYMVPAAVVVVDSLPL 960 Query: 2003 TVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXX 2062 TVNGKLD RALPAP+Y + YRAP + E+ LAGI+A VLG++R Sbjct: 961 TVNGKLDIRALPAPQYGATGSYRAPASPVEEVLAGIYAQVLGLDRVAVDQSFFDLGGDSL 1020 Query: 2063 XAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVS 2109 AMRV AA+N +L DLSVR LF+APTVA+L+ + +G+ T V+ Sbjct: 1021 SAMRVVAAINKSLGGDLSVRALFDAPTVAELAPGIGQGSGQWTPLVA 1067 Score = 684 bits (1766), Expect = 0.0 Identities = 445/1062 (41%), Positives = 589/1062 (55%), Gaps = 75/1062 (7%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ QQ L F VY + ++G LD L A VV RH +L Sbjct: 1073 VVPLSFAQQRLWFIDQLQGPSA--VYNMAWSARLSGELDAAALGAAFADVVGRHESLRTV 1130 Query: 1152 FVEQFGEPVQVLTADPMI--AWRYLDLRGDDLTPDHEIEQLCAA--ERSAVC-DLLERPT 1206 F G Q++ + W+ +D +G +L AA +++ C DL Sbjct: 1131 FRAVAGVAEQLVLGVEQVDVRWQIIDAQG------WSSRRLAAALEQQARHCFDLTVEIP 1184 Query: 1207 FRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPA----AAPYRN 1259 RA+L R + ++H V+ HHI DGWSL L+ ++ Y R P A Y + Sbjct: 1185 LRASLFRVTDDEHVLVVVAHHIAADGWSLRPLVTDLGVAYASRCAGRAPGWAGLAVQYVD 1244 Query: 1260 FVNWLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRV 1305 + W W + L+G + PT A P V RG + Sbjct: 1245 YTLWQRTNLGELTDSHSGIAGQLRYWEKALEGMAERLQLPTDRAYPRVADHRGSGVDVQW 1304 Query: 1306 SAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMV 1365 A+ + + +AR H T V+Q A LL +++G DVA G V+GR D A + +V Sbjct: 1305 PAQLQQQVARVAREHHATSFMVIQTALAVLLAKLSGSSDVAVGVPVAGR-GDPA-LDELV 1362 Query: 1366 GLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQL 1418 G+ +NTV +R +V+ D T LL Q+++ EH+ + LN + ++ H L Sbjct: 1363 GVFVNTVVLRVQVAGDPTFAQLLAQVRTRSLAAFEHQDVPFEVLVERLNPVRSLT-HHPL 1421 Query: 1419 FDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHE---------LGLR 1469 + +++ D SA + + L V EF + ++ G +G Sbjct: 1422 VQVVLAWQN---DMSAELVLDGLDV-EFAPVHTQTARMDLVFSLGERFTDTGAPAGIGGG 1477 Query: 1470 VEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQ 1529 VE+ T VFD + I LI R QR++ AM+ DP RRLSS+D++D E +LD NRAVL + Sbjct: 1478 VEFRTDVFDAASIAALIQRLQRVVVAMVADPDRRLSSVDLLDAAEHARLDVVGNRAVLAE 1537 Query: 1530 PVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVA 1589 P+ P S+P +FA QV E A+ E SL Y ELD AAN+LA+LL G PG V Sbjct: 1538 PLVEPVSVPGLFAAQVASRAEVTALVCEDRSLTYRELDRAANRLAHLLVDQGVGPGDVVG 1597 Query: 1590 LMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGF 1649 L++ RS +A++AILAVLK+GAAYL ID + P R+ FM+ DA PVA +TT L R G+ Sbjct: 1598 LLLERSVEAVIAILAVLKSGAAYLAIDVNHPDGRIGFMIEDAAPVAVITTAGLAQRLAGY 1657 Query: 1650 DLQVVEVDDPAV-EIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLP 1708 + V+++DDPA+ YP L PS D+IAY+IYTSGTTG PKGV ITH N+TQ+ ++ Sbjct: 1658 PVAVIDIDDPAIATCYPGHGLPFPSADNIAYLIYTSGTTGKPKGVGITHHNITQLFTSVA 1717 Query: 1709 AE-LPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 A PG +W+Q HS FD SVWE+WGALLHGGRLV+VPE + S +L ALLV+EGV Sbjct: 1718 ATGFTPAPGQIWTQCHSYAFDYSVWEMWGALLHGGRLVVVPELVTRSAAELLALLVTEGV 1777 Query: 1768 NVLYQTPSAVRMMSPEG---------LEGTALVVAGEACPTEVVDRWAVDR----VMINA 1814 VL QTPSA + E L A+V GEA + W + +IN Sbjct: 1778 GVLSQTPSAFYALQAEDAAQPQLGRQLCLDAVVFGGEALEPARLGPWLANHGRRPRLINM 1837 Query: 1815 YGPTESTIYAAISAPL--SPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXX 1872 YG TE+T++A+ + G V P+G P+ A FVLD WLRPVP GV GELY+A Sbjct: 1838 YGITETTVHASFREIVRHDLGFAVSPVGVPLANLAFFVLDGWLRPVPVGVAGELYVAGAG 1897 Query: 1873 XXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRI 1932 LT +RFVACPFG GARMYRTGD+VRWG DGQLQY+GRADEQVKIRGYRI Sbjct: 1898 VGCGYWRRSGLTASRFVACPFGALGARMYRTGDVVRWGPDGQLQYVGRADEQVKIRGYRI 1957 Query: 1933 ELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPA 1992 ELGE+ AALS +DGVDQAVVIAREDRPGDKRLVGY+ G+ D AR+ L LPAYMVPA Sbjct: 1958 ELGEVAAALSQLDGVDQAVVIAREDRPGDKRLVGYLVGSVDAGQARAALAQALPAYMVPA 2017 Query: 1993 AVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXX 2052 AVV +++LPLTVNGKLD RALPAP+Y + YRAP + E+ LAGI+A VLG++R Sbjct: 2018 AVVVVDSLPLTVNGKLDIRALPAPQYGATGSYRAPASPVEEVLAGIYAQVLGLDRVAVDQ 2077 Query: 2053 XXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 A++V A A R +F TVA L+ Sbjct: 2078 SFFDLGGDSILAIQVVARARAA-GVVCRPRDVFTEQTVAGLA 2118 Score = 644 bits (1660), Expect = 0.0 Identities = 418/959 (43%), Positives = 536/959 (55%), Gaps = 68/959 (7%) Query: 20 EHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRL 79 EH +++V GNRAVL +P PV++P LFA QV + ALV GDRS TYRELD A+NRL Sbjct: 455 EHARLDVVGNRAVLAEPLVEPVSVPGLFAAQVASRAEVTALVCGDRSLTYRELDRAANRL 514 Query: 80 AHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKP 139 AH+L + G PG V L+ RS EA+++IL+VLK+GAAYL +D HPD RIGFM+ DA P Sbjct: 515 AHLLVDQGVGPGDVVGLLLERSVEAVIAILAVLKSGAAYLAIDVNHPDGRIGFMIEDAAP 574 Query: 140 VAALTTADLRSRLDQYDLAVIDMADPAIDR-RPSDALSGPRPDDLAYMTYTSGTTGVPKA 198 VA +TTA L RL Y +AVID+ DPAI P L P D++AY+ YTSGTTG PK Sbjct: 575 VAVITTAGLAQRLAGYPVAVIDIDDPAIATCYPGYGLPFPSADNIAYLIYTSGTTGKPKG 634 Query: 199 VAVTHHNVTQLVSALHAD-LPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESV 257 V +THHN+TQL +++ A PGQ+W+Q HS FD SVWE+WGALLHGGRLVVVPE V Sbjct: 635 VGITHHNITQLFTSVAATGFTPAPGQIWTQCHSYAFDYSVWEMWGALLHGGRLVVVPELV 694 Query: 258 GSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTL---------IVAGEACPTELV 308 S +L LL+TE V VL QTPSA L E L + GEA + Sbjct: 695 TRSAAELLALLVTEGVGVLSQTPSAFYALQAEDAAQPQLGRQLCLDAVVFGGEALEPARL 754 Query: 309 DRWAPGRV----MINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXL--FVLDKWLR 362 W +IN YG TE T++A+ E + L FVLD WLR Sbjct: 755 GPWLANHGRRPRLINMYGITETTVHASFREIVRHDLGFAVSPVGVPLANLAFFVLDGWLR 814 Query: 363 PAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLE 422 P P GV GELYVAG GV GY R LTASRFVACPFG G RMYRTGD+VRWG DGQL+ Sbjct: 815 PVPVGVAGELYVAGAGVGCGYWRRSGLTASRFVACPFGALGARMYRTGDVVRWGPDGQLQ 874 Query: 423 YLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPAQ 482 Y+GRADEQVKIRGYRIELGE+ AAL++LDGVDQAVVIAREDRPGDKRLVGY+ G+ D Q Sbjct: 875 YVGRADEQVKIRGYRIELGEVAAALSQLDGVDQAVVIAREDRPGDKRLVGYLVGSVDAGQ 934 Query: 483 LRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQIL 542 R ALA++LPAYMVP AVVV+D++PLTVNGKLD RALPAP+Y A YRAP++P E++L Sbjct: 935 ARAALAQALPAYMVPAAVVVVDSLPLTVNGKLDIRALPAPQY-GATGSYRAPASPVEEVL 993 Query: 543 ADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARA-RAAGIQCRPRDIFVEQTXXXXXX 601 A +YAQVLG++RV VD SFFDLGGDS+ +M+VVA ++ G R +F T Sbjct: 994 AGIYAQVLGLDRVAVDQSFFDLGGDSLSAMRVVAAINKSLGGDLSVRALFDAPTVAELAP 1053 Query: 602 XXXXXXESHV-VDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDV 655 + G P V A + ++ ++ GP+ +N + + + Sbjct: 1054 GIGQGSGQWTPLVAGERPAVVPLSFAQQRLWFIDQLQGPSAVYNMAWSARLSGELDAAAL 1113 Query: 656 VVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA-------LTDD 708 ++ RH +LR ++ L V + V R + +DA L Sbjct: 1114 GAAFADVVGRHESLRTVFRAVAGVAEQLVLGVEQ---VDVR--WQIIDAQGWSSRRLAAA 1168 Query: 709 VLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIAWAQHC 765 + +AR+ D + A R T LV++ HH+A DG S R L+ DL +A+A C Sbjct: 1169 LEQQARHCFDLTVEIPLRASLFRVTDDEHVLVVVAHHIAADGWSLRPLVTDLGVAYASRC 1228 Query: 766 TGQS---IELPAGGTSFARWSAL-LAEHAKTDTVRDLADAWRAVTSVPQALPP-VQPDTD 820 G++ L + W L E TD+ +A R + + +Q TD Sbjct: 1229 AGRAPGWAGLAVQYVDYTLWQRTNLGE--LTDSHSGIAGQLRYWEKALEGMAERLQLPTD 1286 Query: 821 TYV--TAGQLSASLDVETTRQLLGEVPAAFR---AGVQDILLVAFGLAWTEFLNRSDTPI 875 A + +DV+ QL +V R A ++ A + + SD + Sbjct: 1287 RAYPRVADHRGSGVDVQWPAQLQQQVARVAREHHATSFMVIQTALAVLLAKLSGSSDVAV 1346 Query: 876 GVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVK 934 GV V G G D L VG F V L V+ VAGD ++ V+ Sbjct: 1347 GVPVAGRG-------DPALDELVGVFVN--TVVLRVQ-------VAGDPTFAQLLAQVR 1389 >tr|B2HRT9|B2HRT9_MYCMM Tax_Id=216594 SubName: Full=Non-ribosomal peptide synthetase;[Mycobacterium marinum] Length = 2807 Score = 2169 bits (5621), Expect = 0.0 Identities = 1151/2138 (53%), Positives = 1419/2138 (66%), Gaps = 68/2138 (3%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M AEP R L DLLD +EH++++ WGNRA LT PTP ++PALFA QV R P+A A+ Sbjct: 432 MAAEPGRRLSL-IDLLDPNEHERLDDWGNRAALTKAVPTPGSLPALFAAQVARTPEATAI 490 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 GD S TY +LD S +LA L GA+PG +A L+PR+ I++IL+VLKTGA YLP Sbjct: 491 TDGDVSLTYAQLDAQSTQLAQALTALGARPGELIALLLPRTHRGIIAILAVLKTGAGYLP 550 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP HPD RI FM++D+ P+AA+TT L RL+ YDL VID+ +P D P+ P P Sbjct: 551 IDPMHPDTRIAFMLNDSTPIAAITTGALHPRLNDYDLPVIDIENPPTDTTPATNPPTPTP 610 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPS---GPGQVWSQWHSLVFDVSV 237 DLAY+ YTSG+TG PK V +THHNVTQL+++ + P +VW+QWHS FDVSV Sbjct: 611 HDLAYIIYTSGSTGTPKGVGITHHNVTQLLNSFDPQSTAILFSPNRVWTQWHSYSFDVSV 670 Query: 238 WEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTL- 296 WEIWGALL G RLVVVPE SPD+L LL+ E+V+VL QTPSA L S L Sbjct: 671 WEIWGALLSGARLVVVPEHTAKSPDELLGLLVDERVNVLSQTPSAFYALQAAAEASDELS 730 Query: 297 --------IVAGEACPTELVDRWA------PGRVMINAYGPTEATIYAAMSEPLXXXXXX 342 + AGEA + W PG + N YG TE T++A+ E + Sbjct: 731 SRLQLDAALFAGEALQPHRLTSWMSRHPRRPG--LFNLYGTTETTVHASWREIVGSDTAA 788 Query: 343 XXXXXXXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFG 400 L FVLD WLRP P GVVGELYVAG GV GY R DLT +RFVACPFG Sbjct: 789 DVSPIGTPLPSLGFFVLDGWLRPVPVGVVGELYVAGGGVGLGYWRRADLTGTRFVACPFG 848 Query: 401 ET-GERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVI 459 +T G RMYRTGDLV WG+DGQL YLGRAD QVKIRG+RIE E+ AAL+++ GVDQAVVI Sbjct: 849 QTPGTRMYRTGDLVWWGTDGQLRYLGRADNQVKIRGFRIEPCEVGAALSRMAGVDQAVVI 908 Query: 460 AREDRPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRAL 519 AR D PGD RLVGY TG ADP +LR ALA LP YMVPTA++ + +PLTVNGKLD RAL Sbjct: 909 ARHDHPGDPRLVGYFTGNADPTELRAALATQLPHYMVPTALIPIAELPLTVNGKLDTRAL 968 Query: 520 PAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARAR 579 PA +Y YRAP TPAEQ LA +YAQVLG++RV VDDSFFDLGGDS+ +M+VV+ AR Sbjct: 969 PAVQYGHTQR-YRAPDTPAEQTLAAIYAQVLGLDRVSVDDSFFDLGGDSLSAMRVVSAAR 1027 Query: 580 AAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVV--DEGVGPVVATPIMRWLREVDGPTGQ 637 AAG+ CR RDIF Q + D+GVG V TPIMRW V Sbjct: 1028 AAGLACRTRDIFRHQNVAALARVVEHIGADVCLGDDDGVGSVALTPIMRWFNSVASLVAG 1087 Query: 638 FNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARE 697 +QTV+ Q PAGV + DVVV++QALLDRHA LRL+V ++ WSL G V ARE Sbjct: 1088 LHQTVLVQGPAGVDQADVVVLIQALLDRHAMLRLQV--ARDSDGGWSLQARPPGCVDARE 1145 Query: 698 CLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDL 757 +R + ++ ++L A +RLDPAAG MVSAVWV T+QL+L IHHLAVDGVSWR+LL+DL Sbjct: 1146 LMRQAEVMSGELLAGALSRLDPAAGVMVSAVWVSSTAQLLLAIHHLAVDGVSWRVLLDDL 1205 Query: 758 NIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQP 817 N WAQ+ ++ LPA G+SF +W+ +L ++A V AWR + +VP + Sbjct: 1206 NTGWAQYRRAGAVSLPAAGSSFRQWATMLVDYAYDPAVTAQLAAWRQIAAVPAVIAAPDR 1265 Query: 818 DTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGV 877 + D +AG LS LD TT+ L+ +VPAAF AGV DILL+AF +AW EFL IGV Sbjct: 1266 EVDNAASAGHLSVVLDAATTQALITKVPAAFHAGVHDILLIAFAVAWQEFLADPTGVIGV 1325 Query: 878 DVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQL 937 DVEGHGR DEL+ +DLS TVGWFTTKYPVAL + W Q GD +G +VK +KEQL Sbjct: 1326 DVEGHGRNDELSPGMDLSATVGWFTTKYPVALHAGPIAWPQFCTGDTVVGAVVKDLKEQL 1385 Query: 938 RSLPEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGR------LG-------AGAGELSEEL 984 R++PEGLTYGLLRY N EVD DP I FNYLGR LG +GAG + E Sbjct: 1386 RAVPEGLTYGLLRYQNHEVDFAEPDPPIAFNYLGRFEGFDRLGGSGGWHLSGAGLMLAET 1445 Query: 985 WRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLS 1044 R+ MPL HTV LNA TIDTD GP L A WTWA S FD +L+ Sbjct: 1446 ARV------------MADMPLTHTVALNAVTIDTDAGPQLHAEWTWASSVFDRGALVKLA 1493 Query: 1045 RLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLF 1104 LWF+ALA I AHV GGGGL+P+D+ LTQ QID+L + Y V D+LPLTP+QQGLLF Sbjct: 1494 GLWFDALAAISAHVDAGGGGLSPADLPGLSLTQSQIDDLERSYPVKDLLPLTPLQQGLLF 1553 Query: 1105 HS-TFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQ-FGEPVQV 1162 HS F G Y VQ+ I + G LD RL DAV T + R+PNLAARF EPVQ+ Sbjct: 1554 HSDAFTSG---QAYVVQIGIELAGELDPLRLHDAVQTAITRNPNLAARFAYAGLDEPVQI 1610 Query: 1163 LTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFV 1222 + DP++ W +DL +IE + A +R A+ D+ RAAL++T+ +Q+R + Sbjct: 1611 ILDDPVVPWDVIDLSDG---AQRDIEAVSAGQREALRDISNNCPIRAALVKTAPDQYRLI 1667 Query: 1223 LTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDG 1282 LT HH+V DGWS+ ILL E+F Y L PYR + WL WRE+ G Sbjct: 1668 LTNHHVVCDGWSMSILLGEVFTRYGNGSLATPVPYREHLVWLADQDRDTALLAWREMFSG 1727 Query: 1283 FETPTLVAP--PGVPGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMT 1340 F+TPTLV+ PG ++S +S T AL ELARS H+T+N VLQAA+ QLL +T Sbjct: 1728 FDTPTLVSAQGPGESAQHAVQSLTLSDAATGALNELARSHHSTLNVVLQAAFAQLLAWLT 1787 Query: 1341 GQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLE 1400 G DVAFGT VSGR ADLAG+ESMVGLLINTV +RA+++A TT +L+ QLQ H DTLE Sbjct: 1788 GHHDVAFGTTVSGRSADLAGSESMVGLLINTVAVRARLTATTTTTELIDQLQQFHTDTLE 1847 Query: 1401 HEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMA 1460 + HL L DIH +GH +LFDTLF+YE+YPI+ + +L +T+ + E HYPL+V Sbjct: 1848 YHHLPLGDIHRAAGHPRLFDTLFVYENYPINDLTALCPDQLTITDITSFETTHYPLTVFV 1907 Query: 1461 LPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDE 1520 LPG +LG RVEYDT+ FD + +++LI R Q +L M +P RRLS +D++D +E +LD+ Sbjct: 1908 LPGPQLGFRVEYDTAAFDKTAMDSLIARLQAVLTVMAAEPGRRLSLIDLLDPNEHERLDD 1967 Query: 1521 WANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVY 1580 W NRA LT+ V +P S+P +FA QV R PEA A+T SL Y +LD + QLA L Sbjct: 1968 WGNRAALTKAVPTPGSLPALFAAQVARTPEATAITDGDVSLTYAQLDAQSTQLAQALTAL 2027 Query: 1581 GAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTG 1640 GA PG+ +AL++PR+ I+AILAVLKTGA YLPIDP P R+ FML D+ P+AA+TTG Sbjct: 2028 GARPGELIALLLPRTHRGIIAILAVLKTGAGYLPIDPMHPDTRIAFMLNDSTPIAAITTG 2087 Query: 1641 DLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNV 1700 L R + +DL V+++++P + P+T TP+P D+AY+IYTSG+TG PKGV ITH NV Sbjct: 2088 ALHPRLNDYDLPVIDIENPPTDTTPATNPTTPTPHDLAYIIYTSGSTGTPKGVGITHHNV 2147 Query: 1701 TQVLDTLPAELPA---GPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDD 1757 TQ+L++ + A P VW+QWHS FDVSVWEIWGALL G RLV+VPE A SPD+ Sbjct: 2148 TQLLNSFDPQSTAILFSPNRVWTQWHSYSFDVSVWEIWGALLSGARLVVVPEHTAKSPDE 2207 Query: 1758 LHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGP 1817 LHALLV+E V VL QTPSA +SP+GLE LVV GEACP +VD+WA R MINAYGP Sbjct: 2208 LHALLVAEHVEVLTQTPSAAAALSPQGLESVTLVVGGEACPAGLVDQWAPGRTMINAYGP 2267 Query: 1818 TESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXX 1877 TE+TIYAA+S+PL PGS PIGSPV + FVLD WLRPVP GVVGELY+A Sbjct: 2268 TEATIYAAMSSPLVPGSGATPIGSPVAGASLFVLDGWLRPVPVGVVGELYVAGGGVGLGY 2327 Query: 1878 XXXXXLTGTRFVACPFGE-PGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGE 1936 LTGTRFVACPFG+ PG RMYRTGDLV WG DGQL+YLGRAD QVKIRG+RIE GE Sbjct: 2328 WRRADLTGTRFVACPFGQTPGTRMYRTGDLVWWGTDGQLRYLGRADNQVKIRGFRIEPGE 2387 Query: 1937 IQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVT 1996 + AALS + GVDQAVVIAR D PGD RLVGY TG ADP R+ L +LP YMVP A++ Sbjct: 2388 VGAALSRMAGVDQAVVIARHDHPGDPRLVGYFTGNADPTELRAALATQLPHYMVPTALIP 2447 Query: 1997 LETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXX 2056 + LPLTVNGKLD RALPA +Y QRYRAP+T E+TLA I+A VLG++R Sbjct: 2448 IAELPLTVNGKLDTRALPAVQYGHTQRYRAPDTPVEQTLAAIYAQVLGLDRVSVDDSFFD 2507 Query: 2057 XXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 AMRV +A+NT L+ D++VR LF+APTV L+ Sbjct: 2508 LGGDSLSAMRVVSAINTTLNTDVAVRVLFDAPTVCTLA 2545 Score = 642 bits (1655), Expect = 0.0 Identities = 408/1020 (40%), Positives = 540/1020 (52%), Gaps = 64/1020 (6%) Query: 1125 ITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD 1184 I G + L A+ VV L A +E G VQ + P + + DLR Sbjct: 53 IAGSVTPDLLSQAIRQVVGEAEPLRAAIIEADGHVVQKVVDYPNLDVPFHDLRSC----- 107 Query: 1185 HEIEQLCAAERSAVCDLLER-----PTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILL 1239 + + A R + E P F+ AL + + + ++ HH+V+DG+ +L+ Sbjct: 108 --ADPVAEANRRGLAMHREPMPWNGPLFKFALFQVASEEFYLFVSIHHVVVDGFGYALLV 165 Query: 1240 QEI----------------FAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGF 1283 I F G + A A Y ++ W+E LDG Sbjct: 166 NRIALVYSELSSGAPVSPTFFGSLQTLVAAEAEYEQSDDY------RADLAYWKETLDGV 219 Query: 1284 ETPTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQ 1342 +L G GP S + +LA+ ++V+ AA ++ + G Sbjct: 220 TDHSLAHADGDRGPSATSVSVEIDPAVVDRAEQLAQLAGVRRSSVITAACALMVRQRQGG 279 Query: 1343 RDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHE 1402 V VS R + ++ G+L TVP+ V D V + ++S + H+ Sbjct: 280 PKVVLDFPVSRRTSPQL--MTIPGMLSGTVPLVLTVPPDAEVNAFCQHVESQIKQAVRHQ 337 Query: 1403 HLALNDIHHVSGHEQLFDT----LFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSV 1458 ++ + SG Q F+ P T A G VT + + + + V Sbjct: 338 RFPMHILE--SGAYQQFNEKSAGAVSVNFMPSVTLAPFGGAASTVTILSFAQGEQFGM-V 394 Query: 1459 MALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQL 1518 G L L F ++ L R Q +L M +P RRLS +D++D +E +L Sbjct: 395 FTKDGGRLFLHTVGSGGPFADLDVSDLAARLQAVLTVMAAEPGRRLSLIDLLDPNEHERL 454 Query: 1519 DEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLA 1578 D+W NRA LT+ V +P S+P +FA QV R PEA A+T SL Y +LD + QLA L Sbjct: 455 DDWGNRAALTKAVPTPGSLPALFAAQVARTPEATAITDGDVSLTYAQLDAQSTQLAQALT 514 Query: 1579 VYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVT 1638 GA PG+ +AL++PR+ I+AILAVLKTGA YLPIDP P R+ FML D+ P+AA+T Sbjct: 515 ALGARPGELIALLLPRTHRGIIAILAVLKTGAGYLPIDPMHPDTRIAFMLNDSTPIAAIT 574 Query: 1639 TGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHG 1698 TG L R + +DL V+++++P + P+T TP+P D+AY+IYTSG+TG PKGV ITH Sbjct: 575 TGALHPRLNDYDLPVIDIENPPTDTTPATNPPTPTPHDLAYIIYTSGSTGTPKGVGITHH 634 Query: 1699 NVTQVLDTLPAELPA---GPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSP 1755 NVTQ+L++ + A P VW+QWHS FDVSVWEIWGALL G RLV+VPE A SP Sbjct: 635 NVTQLLNSFDPQSTAILFSPNRVWTQWHSYSFDVSVWEIWGALLSGARLVVVPEHTAKSP 694 Query: 1756 DDLHALLVSEGVNVLYQTPSAVRMMSPEG---------LEGTALVVAGEACPTEVVDRWA 1806 D+L LLV E VNVL QTPSA + L+ A + AGEA + W Sbjct: 695 DELLGLLVDERVNVLSQTPSAFYALQAAAEASDELSSRLQLDAALFAGEALQPHRLTSWM 754 Query: 1807 VDRV----MINAYGPTESTIYAAISAPL--SPGSDVVPIGSPVPKGATFVLDEWLRPVPP 1860 + N YG TE+T++A+ + +DV PIG+P+P FVLD WLRPVP Sbjct: 755 SRHPRRPGLFNLYGTTETTVHASWREIVGSDTAADVSPIGTPLPSLGFFVLDGWLRPVPV 814 Query: 1861 GVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGE-PGARMYRTGDLVRWGDDGQLQYLG 1919 GVVGELY+A LTGTRFVACPFG+ PG RMYRTGDLV WG DGQL+YLG Sbjct: 815 GVVGELYVAGGGVGLGYWRRADLTGTRFVACPFGQTPGTRMYRTGDLVWWGTDGQLRYLG 874 Query: 1920 RADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARS 1979 RAD QVKIRG+RIE E+ AALS + GVDQAVVIAR D PGD RLVGY TG ADP R+ Sbjct: 875 RADNQVKIRGFRIEPCEVGAALSRMAGVDQAVVIARHDHPGDPRLVGYFTGNADPTELRA 934 Query: 1980 ELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIF 2039 L +LP YMVP A++ + LPLTVNGKLD RALPA +Y QRYRAP+T E+TLA I+ Sbjct: 935 ALATQLPHYMVPTALIPIAELPLTVNGKLDTRALPAVQYGHTQRYRAPDTPAEQTLAAIY 994 Query: 2040 AHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEH 2099 A VLG++R AMRV +A A R +F VA L+ VEH Sbjct: 995 AQVLGLDRVSVDDSFFDLGGDSLSAMRVVSAARAA-GLACRTRDIFRHQNVAALARVVEH 1053 >tr|Q740D1|Q740D1_MYCPA Tax_Id=1770 SubName: Full=Putative uncharacterized protein;[Mycobacterium paratuberculosis] Length = 6384 Score = 2153 bits (5579), Expect = 0.0 Identities = 1162/2002 (58%), Positives = 1387/2002 (69%), Gaps = 49/2002 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLT-DPGPTPVTIPALFAEQVVRAPDAVA 59 M A+P+ R L S D+L + EH Q+E GN AVLT PGP V++P LFA QV RAP VA Sbjct: 421 MAADPA-RLLSSLDVLRDPEHAQLEALGNTAVLTRTPGPA-VSVPELFATQVARAPQDVA 478 Query: 60 LVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYL 119 LV RS TYR+LDEASNRLAH+LA GA PG +VA L RS EA+ SIL+VLKTGAAYL Sbjct: 479 LVCEGRSLTYRQLDEASNRLAHLLAGLGAGPGQSVALLFSRSAEAVASILAVLKTGAAYL 538 Query: 120 PVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPR 179 P+DPA P+ RIGFM++DAKPVAAL+TA+L RL+ + + VID+ DP I RP+ AL P Sbjct: 539 PIDPAAPETRIGFMLADAKPVAALSTAELAGRLEGHGMTVIDVNDPRIQDRPATALPVPA 598 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWE 239 D +AY+ YTSGTTGVPK VAVTH NVTQL+ +L A LP P VWSQ HS FDVSVWE Sbjct: 599 ADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSLDAGLP--PAGVWSQCHSYAFDVSVWE 656 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVA 299 I+GALL GGRLVVVPE V +P++LH++L+ E+VSVL QTPSA MLSP+GLES +L+V Sbjct: 657 IFGALLRGGRLVVVPEDVTRAPEELHDVLVNEQVSVLTQTPSAVAMLSPQGLESVSLVVV 716 Query: 300 GEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 GEACP E+VDRW+PGRVM+NAYGPTE T+ A+S PL LFVLD Sbjct: 717 GEACPAEVVDRWSPGRVMVNAYGPTETTMCVAISAPLAPGMGSPPIGVPVDGAGLFVLDA 776 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDG 419 WLRP P GVVGELYV G GVA GY R LTAS FVACPFG G RMYRTGDLV W SDG Sbjct: 777 WLRPVPPGVVGELYVGGAGVACGYWRRGGLTASWFVACPFGAPGARMYRTGDLVCWRSDG 836 Query: 420 QLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD 479 QL+Y GRADEQVK+RGYRIELGE+QAALA LD VDQAVVIAREDRPG KRLVGYITGTAD Sbjct: 837 QLDYRGRADEQVKVRGYRIELGEVQAALAALDDVDQAVVIAREDRPGGKRLVGYITGTAD 896 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 PA++RTALA+ LP YMVP AVV LD IPLT NGKLD RALP PEY + YRAPS E Sbjct: 897 PAEVRTALAQRLPVYMVPAAVVALDAIPLTPNGKLDTRALPTPEYTGSR--YRAPSNAVE 954 Query: 540 QILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXX 599 + +A +YA VLGVERVGVDDSFFDLGGDSI ++QVVARARAAG+ CRPRD+FVEQT Sbjct: 955 ETVAGIYAHVLGVERVGVDDSFFDLGGDSISALQVVARARAAGLTCRPRDVFVEQTVARL 1014 Query: 600 XXXXXXXXES-HVVDEGVGPVVATPIMRWLREVD---GPTGQFNQTVITQAPAGVTEDDV 655 + V DEGVGPV TPIMRWL+ + G T QFNQTV+ QAPAGVTE +V Sbjct: 1015 ARVVGSGDRAAEVADEGVGPVPPTPIMRWLQAAERAGGATDQFNQTVLVQAPAGVTETEV 1074 Query: 656 VVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARN 715 ++LQAL+DRHA LRLRV D + D WS VPEAG+V AR+CLR+VDAL+D+ L+ AR Sbjct: 1075 AIVLQALVDRHAMLRLRVTD--DGADGWSFEVPEAGSVQARDCLRSVDALSDEALLAARA 1132 Query: 716 RLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAG 775 RL+PAAG M++A+WV T QL ++IHHLAVD VSW ILLEDLNIAWA H GQ +EL Sbjct: 1133 RLNPAAGTMLAALWVEATGQLAVIIHHLAVDAVSWWILLEDLNIAWALHRAGQPVELAPA 1192 Query: 776 GTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVE 835 GTSFARW+ LL EHA+ V D W+ VTS P ALP +PD DTY +AG+LS LD E Sbjct: 1193 GTSFARWARLLDEHARDPEVVGQLDRWKTVTSTPAALPAPRPDVDTYASAGRLSVELDAE 1252 Query: 836 TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLS 895 TT LLGEVPAAF AG+ DILL+AFGLAWTEFL PIG+DVEGHGR++EL +D+DLS Sbjct: 1253 TTAMLLGEVPAAFHAGIHDILLIAFGLAWTEFLGEPGAPIGIDVEGHGRHEELGADIDLS 1312 Query: 896 RTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPE 955 RTVGWFT KYPV+L V L W QV AGD ALG ++K KEQLR+LPE LTYGLLRYLN + Sbjct: 1313 RTVGWFTAKYPVSLDVAGLRWPQVAAGDPALGPVLKRAKEQLRTLPEPLTYGLLRYLNTD 1372 Query: 956 VDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGT 1015 VDL G+DP I FNYLGR GA A + + + WRI Q VPMPLMH VELNAGT Sbjct: 1373 VDLAGADPPIAFNYLGRQGA-ASDSAADGWRISQ-DMSLLGAAAAVPMPLMHAVELNAGT 1430 Query: 1016 IDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVR-GGGGGLTPSDVAPAR 1074 IDT GP L A WTWAPS EQ TR+SRLWFEALAG+CAHVR GGGGGLTPSD+APAR Sbjct: 1431 IDTGAGPHLHAEWTWAPSVLGAEQITRVSRLWFEALAGVCAHVRSGGGGGLTPSDIAPAR 1490 Query: 1075 LTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIG--DDVYAVQLDITITGVLDQH 1132 LTQ+QIDEL R+ + D+LPLTP+QQGLLFHS+ A+G DD+YAVQLD T+TG LD Sbjct: 1491 LTQQQIDELQSRHRIADILPLTPLQQGLLFHSSTAQGNDGMDDMYAVQLDFTLTGPLDAD 1550 Query: 1133 RLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT-PDHEIEQLC 1191 RLR+AV TVV RHP+LAA F +Q+ EPVQ++ ADP + WRY++L G D IEQLC Sbjct: 1551 RLREAVRTVVHRHPHLAALFCDQYDEPVQIIPADPAVEWRYVELDGTGAADADDLIEQLC 1610 Query: 1192 AAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL 1251 AAER+AV DL +P FR AL+RT G++HRFVLT HHI++DGWSLPILL+EIFAGY+G RL Sbjct: 1611 AAERAAVADLAGQPVFRTALVRTGGDRHRFVLTSHHILLDGWSLPILLREIFAGYYGQRL 1670 Query: 1252 PAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG--VPGPRGIESYRVSAET 1309 PAA YR F+ WL W EVL GF+TPTLVAP G G RG E V +T Sbjct: 1671 PAAGSYRAFLTWLAERDLDAARRAWGEVLSGFDTPTLVAPEGRLGQGRRGFEKSCVPEQT 1730 Query: 1310 TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSG-RPADLAGAESMVGLL 1368 TRALGELARS HTT++TVLQAAW +L +TG+ DV FGT S ++ AE MVGLL Sbjct: 1731 TRALGELARSCHTTLSTVLQAAWAVVLTSLTGRHDVVFGTPRSRVGQLEVDDAEQMVGLL 1790 Query: 1369 INTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESY 1428 INTVP+RA+++A TT LL QLQ+ HNDTLEH+HLALN+IH V+GH+QLFDTLF+YE+Y Sbjct: 1791 INTVPVRAEITATTTTAQLLAQLQNSHNDTLEHQHLALNEIHRVTGHDQLFDTLFVYENY 1850 Query: 1429 PIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDR 1488 PID+ +G LA+ EF NREYNHYPL+V ALPG ELGL +E+DT VFD + IE+L+ R Sbjct: 1851 PIDSGMTLGADGLAIAEFTNREYNHYPLTVEALPGPELGLHIEFDTDVFDTASIESLVQR 1910 Query: 1489 FQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERD 1548 QR+L AM DP RRLSS+D++D ER + + A ++ P+ P++ A V D Sbjct: 1911 LQRVLVAMSTDPDRRLSSLDLLDRGERELVLSTMSGAGVSAPIG---VAPQLLAAAVAAD 1967 Query: 1549 PEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKT 1608 P+APA+ L+Y ELD+ + +LA L +G P + + + R A+ +VA AV K Sbjct: 1968 PDAPAIVDGARELSYRELDDWSTRLARKLIQHGVGPEHAAGVAIERCAELVVAWWAVTKV 2027 Query: 1609 GAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLR---------SRFDGFDLQVVEVDDP 1659 G Y P++ P R+ +L V +T G R DG DL + Sbjct: 2028 GGVYAPVNLDHPVERIASVLDTVNAVCVLTCGTDEVAGAGPRPILRIDGLDLSGHSTE-- 2085 Query: 1660 AVEIYPSTTLLTPSP---DDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPG 1716 P T SP DD AY+I+TSG+TGVPKGVA++H + G Sbjct: 2086 -----PITDADRRSPLRADDTAYLIFTSGSTGVPKGVAVSHTGLLGWAAAQRELFGLGAD 2140 Query: 1717 AVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA 1776 A S FD SV E+ A G L++ P + + L ALL ++ V TP+ Sbjct: 2141 ARVLMVASPTFDASVGELLLAAGSGAALIVAPPQVYAG-EALTALLHNQRVGTAILTPTV 2199 Query: 1777 VRMMSPEGLEGT-ALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSD 1835 + + L+G LV GEAC E+VD WA R M N YGP+E+TI+ A L+ G Sbjct: 2200 ISTLDRGRLDGLHTLVAVGEACLPELVDGWAPGRQMFNGYGPSETTIWVT-CARLTAGHP 2258 Query: 1836 VVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGE 1895 V IG+P+P VLD WL+PVP GVVGELYL+ LT RFVA PFG Sbjct: 2259 -VRIGAPIPGVCARVLDGWLKPVPVGVVGELYLSGPALGHGYLGRVDLTAERFVANPFGG 2317 Query: 1896 PGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAR 1955 PG RMYRTGDLVRW +G L YLGRAD Q+K+RG RIELGEI+ L V QA V + Sbjct: 2318 PGERMYRTGDLVRWTPEGTLDYLGRADNQIKLRGQRIELGEIENTLLACPQVTQAAVTVQ 2377 Query: 1956 EDRPGDKRLVGYITGTADPAAA 1977 + G +LV Y+T P+ A Sbjct: 2378 DSAAG-SQLVAYVTLDHGPSDA 2398 Score = 850 bits (2195), Expect = 0.0 Identities = 490/1055 (46%), Positives = 639/1055 (60%), Gaps = 53/1055 (5%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ Q L F F +Y + + + ++G LD LR A+ VVARH +L Sbjct: 2946 VIPLSFAQTRLWFIDQFQGP--SPMYNITVALRLSGRLDADALRAALADVVARHESLRTV 3003 Query: 1152 FVEQFGEPVQVLTADPMIAWR--YLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 F G P QV+ I + +D RG P+ + + +A DL Sbjct: 3004 FATADGTPQQVVIPADRIGFACDVVDARG---WPEDRLREAMSAAARYTFDLSAESPLHT 3060 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVN 1262 L ++H V+ HHI DGWS+ +++ Y R P AP Y ++ Sbjct: 3061 ELFARGDDEHVLVVAVHHIAADGWSITPFARDLGVAYASRCAGRDPDWAPLPVQYADYTL 3120 Query: 1263 WLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAE 1308 W W + L G + PT P V RG + AE Sbjct: 3121 WQRAHLGDVDDPGSRIAAQLDFWTDALAGLPERLQLPTDRPYPAVADHRGARLAVDWPAE 3180 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLL 1368 + L +AR T V+QAA+ LL +++ DVA G ++GRP + + ++G Sbjct: 3181 LQQQLRRVAREHDATSFMVVQAAFAALLAKVSASSDVAVGFPIAGRPEPVL--DELIGFF 3238 Query: 1369 INTVPIRA---KVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQL 1418 +NT+ +R ++ D T +LL Q++ EH+ + LN +S H L Sbjct: 3239 VNTLVLRVDLNELGGDPTFAELLAQVRRRSLAAFEHQDVPFELLVERLNPTRSMS-HHPL 3297 Query: 1419 FDTLFLYESYPIDTSA---FMGVQELAVTEF---NNREYNHYPLSV---MALPGHELGLR 1469 L +E++P + +A + + +L VT N S+ G G+ Sbjct: 3298 VQVLLGWENFPGEVTAPAAGLALGDLQVTPMPLHTNTARMDLTFSLAERFTESGQRAGIA 3357 Query: 1470 V--EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 V EY T VFD +E LI+R QRLL A+ DP RRLS++D++D +E +L++W N AVL Sbjct: 3358 VTAEYRTDVFDGRTVEGLIERLQRLLTAVTADPQRRLSAVDLLDANEHARLEKWGNTAVL 3417 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 +P +P S+P FA Q R P+A A+T +G S+ Y ELDEAAN+LA+ + +GA PG+ Sbjct: 3418 ARPA-TPVSVPARFAAQAARTPDAVALTCDGRSMTYRELDEAANRLAHFMIHHGAGPGER 3476 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VAL+ PRSA+AIVAILA LK+GAAYLPIDP++PAAR+EFML DA P+ AVTT L R Sbjct: 3477 VALLFPRSAEAIVAILAALKSGAAYLPIDPALPAARVEFMLTDAAPIVAVTTAALAERLH 3536 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 GFDL V++V DPAV P+T P PDD+A++IYTSGTTGVPKGVA+T NV Q+ D L Sbjct: 3537 GFDLTVIDVADPAVATQPATAPPVPDPDDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDL 3596 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 + P VW+Q+HS FD SVWEIWGALLHGGRLV+VPE+++ SP++ H LLV E V Sbjct: 3597 RIGIELSPRQVWTQFHSYAFDFSVWEIWGALLHGGRLVVVPETVSRSPNEFHDLLVREHV 3656 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAIS 1827 VL QTPSAV ++ +GL+GTALV+ E CP E+VDRWA R M+N YGPTE+T++A S Sbjct: 3657 TVLTQTPSAVGLLRTDGLDGTALVIGAEPCPPELVDRWAPGRTMVNVYGPTETTMWACKS 3716 Query: 1828 APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTR 1887 APL+ GS PIG+PV + A FVLD+WLRPVPPGVVGELYLA LT R Sbjct: 3717 APLTAGSGFPPIGAPVTRAAFFVLDDWLRPVPPGVVGELYLAGDGVGVGYWRRPGLTAAR 3776 Query: 1888 FVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGV 1947 F+ACPFGEPG RMYRTGDLV WG DGQL+YLGRADEQVK+RGYRIELGEIQAALS +DGV Sbjct: 3777 FLACPFGEPGTRMYRTGDLVCWGPDGQLRYLGRADEQVKVRGYRIELGEIQAALSALDGV 3836 Query: 1948 DQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGK 2007 +QAVV+ARED PGDKRLVGY+TG+ PA AR+ L RLPAYMVPAAVV L++LP+TVNGK Sbjct: 3837 EQAVVVAREDNPGDKRLVGYVTGSVAPAKARAALAERLPAYMVPAAVVVLDSLPMTVNGK 3896 Query: 2008 LDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRV 2067 LD RALPAP+Y YRAPE+ TE+ LAGI+A VLGV+R MR+ Sbjct: 3897 LDTRALPAPDYWHTGGYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRL 3956 Query: 2068 TAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 A+N+ALD DL VRT+FEAPT+A+L+ + AG Sbjct: 3957 ITAINSALDTDLPVRTVFEAPTIAQLAPRIAQSAG 3991 Score = 836 bits (2160), Expect = 0.0 Identities = 515/1093 (47%), Positives = 660/1093 (60%), Gaps = 71/1093 (6%) Query: 1045 RLWFEA--LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGL 1102 R FEA +A + + GGL P VA R DV+PL+ Q L Sbjct: 3971 RTVFEAPTIAQLAPRIAQSAGGLAPL-VAAGR---------------PDVVPLSFAQNRL 4014 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 F ++G +Y + + + G LD L A+ VVARH +L F G P Q+ Sbjct: 4015 WFIDQ-SQG-PSPLYNMAAALRLRGRLDAGALGAALGDVVARHESLRTVFPSHQGTPRQL 4072 Query: 1163 LTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFV 1222 + + + + D D + + R DL RA L S ++H V Sbjct: 4073 VVPAERAEFGWDVIDATDWPADRLDDAVQDVTRHTF-DLAAEIPIRAKLFAVSEDEHVLV 4131 Query: 1223 LTFHHIVIDGWSLPIL---LQEIFAGYFGHRLPAAAP----YRNFVNWLXXXXXXXXXXX 1275 + HHI DG SL L L + +A P A Y ++ W Sbjct: 4132 IVVHHIAADGMSLTPLGVDLSQAYASRCAGHAPGWADLPVQYCDYTLWQRAQFGDLNDPD 4191 Query: 1276 ---------WREVLDGFET----PTLVAPPGVPGPRGIESYRVS--AETTRALGELARSQ 1320 W + L G PT P RG +S V AE + + +AR Sbjct: 4192 SRIGTQLAYWEDALAGMPERLALPTDRPYPAAADQRG-DSVAVDWPAELQQQVRRIAREH 4250 Query: 1321 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAKV 1378 + T V+QAA LL ++ DVA G ++GR PA + +VG +NT+ +R + Sbjct: 4251 NATSFMVVQAALAVLLSKIGASSDVAVGFPIAGRRDPA----LDQLVGFFVNTLVLRIDL 4306 Query: 1379 SADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYP-- 1429 + D + +LL +Q+ EH+ + LN ++ H L + ++++ Sbjct: 4307 TGDPSFAELLALVQARSLAAFEHQDVPFEVLVERLNPTRSLT-HHPLVQVMLAWQNFAGH 4365 Query: 1430 IDTSAFMGVQELAVTEFNNREYNHYPLSVMAL-----PGHE---LGLRVEYDTSVFDVSE 1481 D +A + + +L VT + + V +L P E +G RVE+ T VFD + Sbjct: 4366 DDPAAALALGDLDVTSVPVHDQSARMDLVFSLAERWNPDGEFAGIGGRVEFRTDVFDAAT 4425 Query: 1482 IETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVF 1541 IETLI+R +R+LEAM DP R LS++D++DD ER L+E N A+LT+P S+PE+F Sbjct: 4426 IETLIERLRRVLEAMTGDPGRPLSAVDLLDDAERAYLEEVGNTAILTRPASGRVSVPELF 4485 Query: 1542 ARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVA 1601 A QV R PE A+ + S+ Y +LDEA+N+LA+ LA GA PG++VAL+ RSA+A+ A Sbjct: 4486 ATQVARVPETVALVCDDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAA 4545 Query: 1602 ILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAV 1661 ILAVLKTGAAYLPIDPS P R+EFMLGDA+P+AAVTT +L R G + VV+VDDP + Sbjct: 4546 ILAVLKTGAAYLPIDPSAPQTRVEFMLGDAEPIAAVTTAELAQRLAGRPVTVVDVDDPGI 4605 Query: 1662 EIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQ 1721 + P+T L P PD IAY+IYTSGTTG PKGVA+TH NVTQ+L +L A LP+ PG VWSQ Sbjct: 4606 DTLPNTALPLPDPDGIAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPS-PG-VWSQ 4663 Query: 1722 WHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS 1781 HSL FDVSVWEI+GALL GGR+V++PE++A SP DLH L++ V VL QTPSAV M+S Sbjct: 4664 CHSLAFDVSVWEIFGALLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSAVAMLS 4723 Query: 1782 PEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGS 1841 P+GLE +LV+AGEACP EVVD+WA RVM+N YGPTE+++ +ISAPL+ GS + PIGS Sbjct: 4724 PQGLESVSLVLAGEACPPEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGS 4783 Query: 1842 PVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMY 1901 PV A FVLDE LRPVPPGVVGELY+A LT RFVACPFG PGARMY Sbjct: 4784 PVDGAALFVLDESLRPVPPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPGARMY 4843 Query: 1902 RTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGD 1961 RTGDLVRW DGQL YLGRADEQVK+RGYRIELGEIQAALS +DGV+QAVV+ARED PGD Sbjct: 4844 RTGDLVRWRADGQLDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGD 4903 Query: 1962 KRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSA 2021 KRLVGYITGTADPA AR+ L RLPAYMVPAAV+ L+ +PLT NGKLD RALPAP+Y +A Sbjct: 4904 KRLVGYITGTADPAEARARLGERLPAYMVPAAVLGLDAIPLTPNGKLDARALPAPDY-AA 4962 Query: 2022 QRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSV 2081 YRAPE+ TE+ LAGI+A VLGV+R AMR+ AAVN AL+ADL V Sbjct: 4963 GEYRAPESPTEEILAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPV 5022 Query: 2082 RTLFEAPTVAKLS 2094 RT+FEAPTVA L+ Sbjct: 5023 RTVFEAPTVAALA 5035 Score = 811 bits (2095), Expect = 0.0 Identities = 500/1103 (45%), Positives = 634/1103 (57%), Gaps = 77/1103 (6%) Query: 1045 RLWFEA--LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGL 1102 R FEA +A + + GG GL P A R T V+PL+ Q L Sbjct: 5023 RTVFEAPTVAALAPRIGEGGSGLEPL-TAGERPT---------------VVPLSFAQNRL 5066 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 F VY + + + G LD L A+ VVARH +L F G P QV Sbjct: 5067 WFLDQLQGP--SPVYNMAAALRLDGPLDTEALGAALGDVVARHESLRTLFAAPEGRPQQV 5124 Query: 1163 LTADPM--IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHR 1220 + W +D G ++++ A DL + RA L R ++H Sbjct: 5125 VLPAERADFGWEVVDASGWSAD---QLDEAIGATARYTFDLAAQIPLRAELFRLRDDRHV 5181 Query: 1221 FVLTFHHIVIDGWSLPILLQEIFAGYFGHR-------LPAAAPYRNFVNWLXXXXXXXXX 1273 V HHI DG S+ L++++ A Y P Y ++ W Sbjct: 5182 LVAVVHHIAADGMSITPLVRDLGAAYARRCDGRGPDWTPLPVQYVDYTLWQRAQFGELAD 5241 Query: 1274 XX---------WREVLDGFET----PTLVAPPGVPGPRGIE-SYRVSAETTRALGELARS 1319 W++ L G PT P V RG AE + +G++A Sbjct: 5242 SGSRIAAQLAYWQDALAGMPERLALPTDRPYPLVADQRGATVEIDWPAELQQRIGDVAHR 5301 Query: 1320 QHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGLLINTVPIRAK 1377 + T V+Q A T LL ++ DVA G ++GR PA + +VG +NT+ +R Sbjct: 5302 HNATSFMVIQTALTVLLAKLGANPDVAVGFPIAGRRDPA----LDDLVGFFVNTLVLRVD 5357 Query: 1378 VSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFDTLFLYESYP- 1429 + D + +LL ++++ + EH+ + LN ++ H L + ++++ Sbjct: 5358 AAGDPSFTELLARVRTRSLEAFEHQDVPFEVLVERLNPTRSLT-HHPLVQVMLAWQNFAG 5416 Query: 1430 IDTSAFMG-------VQELAVTEFNNREYNHYPLSVMALPGHE---LGLRVEYDTSVFDV 1479 DT G + + V R + + E +G VE+ T VFD Sbjct: 5417 QDTGPAAGLSLGDVEITPIPVDTHTARMDLTFSVGERWCESGEPGGIGGTVEFRTDVFDP 5476 Query: 1480 SEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPE 1539 I+TLI R +R+LEAM DDP + + S+D++D E +LD NRA LT P S+P Sbjct: 5477 DSIQTLIGRLRRVLEAMTDDPTQSVWSVDLLDAGEHARLDTLGNRAALTGPPPRFDSLPT 5536 Query: 1540 VFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAI 1599 +FA Q R P+A A+ G + Y ELDEAAN++A+LL V GA PG +VAL+ RSA+AI Sbjct: 5537 LFAEQAARTPDAVALVCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVALLFSRSAEAI 5596 Query: 1600 VAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDG-FDLQVVEVDD 1658 VAIL VLK+GAAYLPIDP++P R+ FML DA P+ A++T +L R G D+ V++V D Sbjct: 5597 VAILGVLKSGAAYLPIDPALPGERIGFMLADAAPMVAISTAELAPRLHGQHDVPVIDVHD 5656 Query: 1659 PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAV 1718 PA+E PS+ L P DDIAY+IYTSGTTGVPKGVA++H NVTQ+L T + LP V Sbjct: 5657 PAIEAAPSSALPPPGADDIAYLIYTSGTTGVPKGVAVSHRNVTQLL-TADSGLPRE--GV 5713 Query: 1719 WSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVR 1778 WSQWHSL FDVSVWEI+GALLHGGRLV++P+S+ SPDD HALL+ E V+VL QTPSA Sbjct: 5714 WSQWHSLAFDVSVWEIFGALLHGGRLVVIPDSVVRSPDDFHALLLDEQVSVLSQTPSAAG 5773 Query: 1779 MMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDV-V 1837 +SPEGLE LVVAGEACP E+VDRWA R MINAYGPTE+T+Y AISAPL PGS V Sbjct: 5774 TLSPEGLEDLTLVVAGEACPAELVDRWAPGRTMINAYGPTEATVYTAISAPLQPGSPAGV 5833 Query: 1838 PIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPG 1897 PIG PVP FVLDE LRPVPPGVVGELY+ LT + FVACPFG PG Sbjct: 5834 PIGFPVPGAGLFVLDESLRPVPPGVVGELYVGGAGVACGYWRRGGLTASWFVACPFGAPG 5893 Query: 1898 ARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARED 1957 ARMYRTGDLV W DGQL Y GRADEQVK+RGYRIELGE+QAAL+ +D V+QAVVIARED Sbjct: 5894 ARMYRTGDLVCWRSDGQLDYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAVVIARED 5953 Query: 1958 RPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPE 2017 RPG KRLVGYITGTADPA R+ L RLP YMVPAAVV L+ +PLT NGKLD RALP PE Sbjct: 5954 RPGGKRLVGYITGTADPAEVRTALAQRLPVYMVPAAVVALDAIPLTPNGKLDTRALPTPE 6013 Query: 2018 YQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDA 2077 Y + RYRAP E+T+AGI+AHVLGVER AMRV A+N +L Sbjct: 6014 Y-TGSRYRAPSNAVEETVAGIYAHVLGVERVGVDDSFFDLGGDSISAMRVITAINASLGV 6072 Query: 2078 DLSVRTLFEAPTVAKLSLHVEHD 2100 +L+VRTLFEAPTVA LS + D Sbjct: 6073 ELAVRTLFEAPTVASLSWRAQTD 6095 Score = 765 bits (1975), Expect = 0.0 Identities = 450/924 (48%), Positives = 575/924 (62%), Gaps = 38/924 (4%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P R L + DLLD+ E +E GN A+LT P V++P LFA QV R P+ VAL Sbjct: 4440 MTGDPG-RPLSAVDLLDDAERAYLEEVGNTAILTRPASGRVSVPELFATQVARVPETVAL 4498 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V D S TYR+LDEASNRLAH LA GA PG TVA L RS EA+ +IL+VLKTGAAYLP Sbjct: 4499 VCDDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVALLFSRSAEAVAAILAVLKTGAAYLP 4558 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DP+ P R+ FM+ DA+P+AA+TTA+L RL + V+D+ DP ID P+ AL P P Sbjct: 4559 IDPSAPQTRVEFMLGDAEPIAAVTTAELAQRLAGRPVTVVDVDDPGIDTLPNTALPLPDP 4618 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 D +AY+ YTSGTTG PK VAVTHHNVTQL+ +L A LPS PG VWSQ HSL FDVSVWEI Sbjct: 4619 DGIAYLIYTSGTTGAPKGVAVTHHNVTQLLGSLDAGLPS-PG-VWSQCHSLAFDVSVWEI 4676 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 +GALL GGR+VV+PE+V SP DLH+ LI V+VL QTPSA MLSP+GLES +L++AG Sbjct: 4677 FGALLRGGRVVVMPEAVARSPHDLHDALIARHVTVLTQTPSAVAMLSPQGLESVSLVLAG 4736 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP E+VD+WAPGRVM+N YGPTE ++ ++S PL LFVLD+ Sbjct: 4737 EACPPEVVDQWAPGRVMVNGYGPTETSMCVSISAPLTAGSGIPPIGSPVDGAALFVLDES 4796 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELYVAG GVA GY+GRP LTA+RFVACPFG G RMYRTGDLVRW +DGQ Sbjct: 4797 LRPVPPGVVGELYVAGSGVAAGYLGRPSLTAARFVACPFGAPGARMYRTGDLVRWRADGQ 4856 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L+YLGRADEQVK+RGYRIELGEIQAAL+ LDGV+QAVV+ARED PGDKRLVGYITGTADP Sbjct: 4857 LDYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYITGTADP 4916 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A+ R L E LPAYMVP AV+ LD IPLT NGKLD RALPAP+Y AA +YRAP +P E+ Sbjct: 4917 AEARARLGERLPAYMVPAAVLGLDAIPLTPNGKLDARALPAPDY--AAGEYRAPESPTEE 4974 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXX 599 ILA +YA+VLGV+RVGVDDSFFDLGGDSI +M+++A AA R +F T Sbjct: 4975 ILAGIYAEVLGVQRVGVDDSFFDLGGDSISAMRLIAAVNAALNADLPVRTVFEAPTVAAL 5034 Query: 600 XXXXXXXXES-HVVDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTED 653 + G P V A + +L ++ GP+ +N + + + Sbjct: 5035 APRIGEGGSGLEPLTAGERPTVVPLSFAQNRLWFLDQLQGPSPVYNMAAALRLDGPLDTE 5094 Query: 654 DVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR----TVDALTDDV 709 + L ++ RH +LR + + +++P A E + + D L + + Sbjct: 5095 ALGAALGDVVARHESLRTLFAAPEGRPQQ--VVLPAERADFGWEVVDASGWSADQLDEAI 5152 Query: 710 LVEARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCT 766 AR D AA + A R + LV ++HH+A DG+S L+ DL A+A+ C Sbjct: 5153 GATARYTFDLAAQIPLRAELFRLRDDRHVLVAVVHHIAADGMSITPLVRDLGAAYARRCD 5212 Query: 767 GQSIE---LPAGGTSFARWS-ALLAEHAKTDT--VRDLADAWRAVTSVPQALPPVQPDTD 820 G+ + LP + W A E A + + LA A+ +P+ L + D Sbjct: 5213 GRGPDWTPLPVQYVDYTLWQRAQFGELADSGSRIAAQLAYWQDALAGMPERL-ALPTDRP 5271 Query: 821 TYVTAGQLSASLDVE---TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGV 877 + A Q A+++++ +Q +G+V A ++ A + + D +G Sbjct: 5272 YPLVADQRGATVEIDWPAELQQRIGDVAHRHNATSFMVIQTALTVLLAKLGANPDVAVGF 5331 Query: 878 DVEGHGRYDELASDVDLSRTVGWF 901 + G D L VG+F Sbjct: 5332 PIAGR-------RDPALDDLVGFF 5348 Score = 754 bits (1946), Expect = 0.0 Identities = 416/805 (51%), Positives = 521/805 (64%), Gaps = 34/805 (4%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+P R L + DLLD +EH ++E WGN AVL P TPV++PA FA Q R PDAVAL Sbjct: 3386 VTADPQRR-LSAVDLLDANEHARLEKWGNTAVLARPA-TPVSVPARFAAQAARTPDAVAL 3443 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 RS TYRELDEA+NRLAH + HGA PG VA L PRS EAI++IL+ LK+GAAYLP Sbjct: 3444 TCDGRSMTYRELDEAANRLAHFMIHHGAGPGERVALLFPRSAEAIVAILAALKSGAAYLP 3503 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 +DPA P AR+ FM++DA P+ A+TTA L RL +DL VID+ADPA+ +P+ A P P Sbjct: 3504 IDPALPAARVEFMLTDAAPIVAVTTAALAERLHGFDLTVIDVADPAVATQPATAPPVPDP 3563 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+A++ YTSGTTGVPK VAVT +NV QL L + P QVW+Q+HS FD SVWEI Sbjct: 3564 DDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDLRIGIELSPRQVWTQFHSYAFDFSVWEI 3623 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 WGALLHGGRLVVVPE+V SP++ H+LL+ E V+VL QTPSA G+L +GL+ T L++ Sbjct: 3624 WGALLHGGRLVVVPETVSRSPNEFHDLLVREHVTVLTQTPSAVGLLRTDGLDGTALVIGA 3683 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 E CP ELVDRWAPGR M+N YGPTE T++A S PL FVLD W Sbjct: 3684 EPCPPELVDRWAPGRTMVNVYGPTETTMWACKSAPLTAGSGFPPIGAPVTRAAFFVLDDW 3743 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GVVGELY+AG GV GY RP LTA+RF+ACPFGE G RMYRTGDLV WG DGQ Sbjct: 3744 LRPVPPGVVGELYLAGDGVGVGYWRRPGLTAARFLACPFGEPGTRMYRTGDLVCWGPDGQ 3803 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 L YLGRADEQVK+RGYRIELGEIQAAL+ LDGV+QAVV+ARED PGDKRLVGY+TG+ P Sbjct: 3804 LRYLGRADEQVKVRGYRIELGEIQAALSALDGVEQAVVVAREDNPGDKRLVGYVTGSVAP 3863 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 A+ R ALAE LPAYMVP AVVVLD++P+TVNGKLD RALPAP+Y YRAP +P E+ Sbjct: 3864 AKARAALAERLPAYMVPAAVVVLDSLPMTVNGKLDTRALPAPDYWHTGG-YRAPESPTEE 3922 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRP-RDIFVEQTXXXX 599 ILA +YA+VLGV+RVGVDDSFFDLGGDS+ +M+++ +A P R +F T Sbjct: 3923 ILAGIYAEVLGVQRVGVDDSFFDLGGDSLTTMRLITAINSALDTDLPVRTVFEAPTIAQL 3982 Query: 600 XXXXXXXXESHVVDEGVGPVVA------TPI------MRWLREVDGPTGQFNQTVITQAP 647 G+ P+VA P+ + ++ + GP+ +N + Sbjct: 3983 APRIAQSA------GGLAPLVAAGRPDVVPLSFAQNRLWFIDQSQGPSPLYNMAAALRLR 4036 Query: 648 AGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRT----VD 703 + + L ++ RH +LR V + + T L+VP A + + D Sbjct: 4037 GRLDAGALGAALGDVVARHESLR-TVFPSHQGTPR-QLVVPAERAEFGWDVIDATDWPAD 4094 Query: 704 ALTDDVLVEARNRLDPAAGAMVSA---VWVRETSQLVLMIHHLAVDGVSWRILLEDLNIA 760 L D V R+ D AA + A + LV+++HH+A DG+S L DL+ A Sbjct: 4095 RLDDAVQDVTRHTFDLAAEIPIRAKLFAVSEDEHVLVIVVHHIAADGMSLTPLGVDLSQA 4154 Query: 761 WAQHCTGQS---IELPAGGTSFARW 782 +A C G + +LP + W Sbjct: 4155 YASRCAGHAPGWADLPVQYCDYTLW 4179 Score = 737 bits (1903), Expect = 0.0 Identities = 393/598 (65%), Positives = 452/598 (75%), Gaps = 9/598 (1%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MT +P T+++ S DLLD EH +++ GNRA LT P P ++P LFAEQ R PDAVAL Sbjct: 5493 MTDDP-TQSVWSVDLLDAGEHARLDTLGNRAALTGPPPRFDSLPTLFAEQAARTPDAVAL 5551 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V G R TYRELDEA+NR+AH+L GA PG TVA L RS EAI++IL VLK+GAAYLP Sbjct: 5552 VCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVALLFSRSAEAIVAILGVLKSGAAYLP 5611 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLD-QYDLAVIDMADPAIDRRPSDALSGPR 179 +DPA P RIGFM++DA P+ A++TA+L RL Q+D+ VID+ DPAI+ PS AL P Sbjct: 5612 IDPALPGERIGFMLADAAPMVAISTAELAPRLHGQHDVPVIDVHDPAIEAAPSSALPPPG 5671 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWE 239 DD+AY+ YTSGTTGVPK VAV+H NVTQL++A + LP VWSQWHSL FDVSVWE Sbjct: 5672 ADDIAYLIYTSGTTGVPKGVAVSHRNVTQLLTA-DSGLPREG--VWSQWHSLAFDVSVWE 5728 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVA 299 I+GALLHGGRLVV+P+SV SPDD H LL+ E+VSVL QTPSAAG LSPEGLE TL+VA Sbjct: 5729 IFGALLHGGRLVVIPDSVVRSPDDFHALLLDEQVSVLSQTPSAAGTLSPEGLEDLTLVVA 5788 Query: 300 GEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX-LFVLD 358 GEACP ELVDRWAPGR MINAYGPTEAT+Y A+S PL LFVLD Sbjct: 5789 GEACPAELVDRWAPGRTMINAYGPTEATVYTAISAPLQPGSPAGVPIGFPVPGAGLFVLD 5848 Query: 359 KWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSD 418 + LRP P GVVGELYV G GVA GY R LTAS FVACPFG G RMYRTGDLV W SD Sbjct: 5849 ESLRPVPPGVVGELYVGGAGVACGYWRRGGLTASWFVACPFGAPGARMYRTGDLVCWRSD 5908 Query: 419 GQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA 478 GQL+Y GRADEQVK+RGYRIELGE+QAALA LD V+QAVVIAREDRPG KRLVGYITGTA Sbjct: 5909 GQLDYRGRADEQVKVRGYRIELGEVQAALAGLDDVEQAVVIAREDRPGGKRLVGYITGTA 5968 Query: 479 DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPA 538 DPA++RTALA+ LP YMVP AVV LD IPLT NGKLD RALP PEY + YRAPS Sbjct: 5969 DPAEVRTALAQRLPVYMVPAAVVALDAIPLTPNGKLDTRALPTPEY--TGSRYRAPSNAV 6026 Query: 539 EQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQT 595 E+ +A +YA VLGVERVGVDDSFFDLGGDSI +M+V+ A+ G++ R +F T Sbjct: 6027 EETVAGIYAHVLGVERVGVDDSFFDLGGDSISAMRVITAINASLGVELAVRTLFEAPT 6084 Score = 736 bits (1899), Expect = 0.0 Identities = 452/1015 (44%), Positives = 579/1015 (57%), Gaps = 50/1015 (4%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 + I G +D L + VV +L A F E G+ Q + + DL G Sbjct: 36 VRIDGAIDPALLHQTMRHVVGEAESLRASFFEADGQVFQKAVEYSDVDLTFYDLSGSS-D 94 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 P+ E+ ++ A+ + L P + AL RT ++ + T HHI IDG + ++ + I Sbjct: 95 PEREVREMTASIQRTPMPLTG-PMIKFALFRTGSAEYYWFTTCHHIAIDGMGIALVGRRI 153 Query: 1243 FAGYF----GHRLPAA--APYRNFVN-----------------WLXXXXXXXXXXXWREV 1279 A Y G +P A ++ V WL Sbjct: 154 AAVYTALASGKPIPPAFFGSLQDLVGGELEYEASAKFLEDKDYWLAHRPGDGTAGHPPRP 213 Query: 1280 LDGFETPTLVAPPGVPGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRM 1339 D P +PP I S + E ++ALG S T +L W Sbjct: 214 ADDGRDPYSPSPPVQLDESVIGSVK---ELSKALGIRRSSVLTAACALLVRGWCA----- 265 Query: 1340 TGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTL 1399 G +V VS R + ++ G+L VP+ A T D R + + L Sbjct: 266 DGSDEVVLDFPVSRRVDPKS--KTHPGMLAGVVPLVLHAPAAATFADFCRHVDQRSREAL 323 Query: 1400 EHEHL---ALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPL 1456 H+ L+ SG Q + + + P + + T + H+ L Sbjct: 324 RHQQFPTRTLDGEGDFSGPRQAPNRVVV-NFVPARLTLSLADVPATATYTSFGPVGHFGL 382 Query: 1457 SVMALPGHELGLRVEYDTSV--FDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDE 1514 + + V + FD ++ L +R QR+L AM DPAR LSS+DV+ D E Sbjct: 383 FFLGFGDQQFLSTVGTGQPLANFDATD---LAERLQRILAAMAADPARLLSSLDVLRDPE 439 Query: 1515 RTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLA 1574 QL+ N AVLT+ S+PE+FA QV R P+ A+ EG SL Y +LDEA+N+LA Sbjct: 440 HAQLEALGNTAVLTRTPGPAVSVPELFATQVARAPQDVALVCEGRSLTYRQLDEASNRLA 499 Query: 1575 NLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPV 1634 +LLA GA PG+SVAL+ RSA+A+ +ILAVLKTGAAYLPIDP+ P R+ FML DAKPV Sbjct: 500 HLLAGLGAGPGQSVALLFSRSAEAVASILAVLKTGAAYLPIDPAAPETRIGFMLADAKPV 559 Query: 1635 AAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVA 1694 AA++T +L R +G + V++V+DP ++ P+T L P+ D +AY+IYTSGTTGVPKGVA Sbjct: 560 AALSTAELAGRLEGHGMTVIDVNDPRIQDRPATALPVPAADGVAYVIYTSGTTGVPKGVA 619 Query: 1695 ITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGS 1754 +TH NVTQ+L +L A LP P VWSQ HS FDVSVWEI+GALL GGRLV+VPE + + Sbjct: 620 VTHRNVTQLLGSLDAGLP--PAGVWSQCHSYAFDVSVWEIFGALLRGGRLVVVPEDVTRA 677 Query: 1755 PDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINA 1814 P++LH +LV+E V+VL QTPSAV M+SP+GLE +LVV GEACP EVVDRW+ RVM+NA Sbjct: 678 PEELHDVLVNEQVSVLTQTPSAVAMLSPQGLESVSLVVVGEACPAEVVDRWSPGRVMVNA 737 Query: 1815 YGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXX 1874 YGPTE+T+ AISAPL+PG PIG PV FVLD WLRPVPPGVVGELY+ Sbjct: 738 YGPTETTMCVAISAPLAPGMGSPPIGVPVDGAGLFVLDAWLRPVPPGVVGELYVGGAGVA 797 Query: 1875 XXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIEL 1934 LT + FVACPFG PGARMYRTGDLV W DGQL Y GRADEQVK+RGYRIEL Sbjct: 798 CGYWRRGGLTASWFVACPFGAPGARMYRTGDLVCWRSDGQLDYRGRADEQVKVRGYRIEL 857 Query: 1935 GEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAV 1994 GE+QAAL+ +D VDQAVVIAREDRPG KRLVGYITGTADPA R+ L RLP YMVPAAV Sbjct: 858 GEVQAALAALDDVDQAVVIAREDRPGGKRLVGYITGTADPAEVRTALAQRLPVYMVPAAV 917 Query: 1995 VTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXX 2054 V L+ +PLT NGKLD RALP PEY + RYRAP E+T+AGI+AHVLGVER Sbjct: 918 VALDAIPLTPNGKLDTRALPTPEY-TGSRYRAPSNAVEETVAGIYAHVLGVERVGVDDSF 976 Query: 2055 XXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVS 2109 A++V A A R +F TVA+L+ V +G+R V+ Sbjct: 977 FDLGGDSISALQVVARARAA-GLTCRPRDVFVEQTVARLARVV--GSGDRAAEVA 1028 Score = 147 bits (372), Expect = 2e-32 Identities = 132/426 (30%), Positives = 195/426 (45%), Gaps = 31/426 (7%) Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 AQ+R L LP YMVPT +V LD P+T +GKLDR+ALPAP+Y+ A + YRAPST E+ Sbjct: 2806 AQVRERLNAWLPEYMVPTHIVALDEFPMTTSGKLDRKALPAPDYQDA-DRYRAPSTAVEE 2864 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXX 599 IL +Y QVLG+ERVGVDDSFFDLGGDS+ +M+++A A+ R +F T Sbjct: 2865 ILVGIYGQVLGLERVGVDDSFFDLGGDSLSAMRLIAAVNASLNTDLGVRTVFEAPTAAEL 2924 Query: 600 XXXXXXXXE-SHVVDEGVGPVV-----ATPIMRWLREVDGPTGQFNQTVITQAPAGVTED 653 + + G P V A + ++ + GP+ +N TV + + D Sbjct: 2925 ALRVGSEADRPEPLVAGERPAVIPLSFAQTRLWFIDQFQGPSPMYNITVALRLSGRLDAD 2984 Query: 654 DVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVP------EAGAVGARECLRTVDALTD 707 + L ++ RH +LR V T + T + +++P V AR D L + Sbjct: 2985 ALRAALADVVARHESLR-TVFATADGTPQ-QVVIPADRIGFACDVVDARGW--PEDRLRE 3040 Query: 708 DVLVEARNRLD-PAAGAMVSAVWVRETSQ--LVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 + AR D A + + ++ R + LV+ +HH+A DG S DL +A+A Sbjct: 3041 AMSAAARYTFDLSAESPLHTELFARGDDEHVLVVAVHHIAADGWSITPFARDLGVAYASR 3100 Query: 765 CTGQSIE---LPAGGTSFARWSALLAEHAKTDTVRDLA--DAWR-AVTSVPQALPPVQPD 818 C G+ + LP + W R A D W A+ +P+ L + D Sbjct: 3101 CAGRDPDWAPLPVQYADYTLWQRAHLGDVDDPGSRIAAQLDFWTDALAGLPERL-QLPTD 3159 Query: 819 TDTYVTAGQLSASLDVE---TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPI 875 A A L V+ +Q L V A ++ AF + SD + Sbjct: 3160 RPYPAVADHRGARLAVDWPAELQQQLRRVAREHDATSFMVVQAAFAALLAKVSASSDVAV 3219 Query: 876 GVDVEG 881 G + G Sbjct: 3220 GFPIAG 3225 Score = 124 bits (311), Expect = 2e-25 Identities = 64/127 (50%), Positives = 80/127 (62%) Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKT 2034 A R L LP YMVP +V L+ P+T +GKLDR+ALPAP+YQ A RYRAP T E+ Sbjct: 2806 AQVRERLNAWLPEYMVPTHIVALDEFPMTTSGKLDRKALPAPDYQDADRYRAPSTAVEEI 2865 Query: 2035 LAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 L GI+ VLG+ER AMR+ AAVN +L+ DL VRT+FEAPT A+L+ Sbjct: 2866 LVGIYGQVLGLERVGVDDSFFDLGGDSLSAMRLIAAVNASLNTDLGVRTVFEAPTAAELA 2925 Query: 2095 LHVEHDA 2101 L V +A Sbjct: 2926 LRVGSEA 2932 >tr|B1MLB3|B1MLB3_MYCA9 Tax_Id=561007 SubName: Full=Probable non-ribosomal peptide synthetase PstA;[Mycobacterium abscessus] Length = 2716 Score = 1709 bits (4425), Expect = 0.0 Identities = 902/1567 (57%), Positives = 1113/1567 (71%), Gaps = 44/1567 (2%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 MTA+ S R L + D+LD +E +++ WGNRA L P T V+IPALFA+QV R P AVA+ Sbjct: 1074 MTAD-SARPLSAIDVLDAEELARLDEWGNRAELAQP-VTSVSIPALFAQQVSRVPGAVAV 1131 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 S +Y+ELDEASNRLAH L E+GA PG VA L RS EAI++I+ VLKTGAAY+P Sbjct: 1132 SSAGGHLSYQELDEASNRLAHKLIEYGAGPGERVALLFARSAEAIVAIMGVLKTGAAYVP 1191 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPS-DALSGPR 179 VDP+ PDAR+ F+++DA+P A+TT+DL RLD + VID+ DP + +P+ L+ Sbjct: 1192 VDPSVPDARLEFVLADAEPAVAVTTSDLMDRLDACGVVVIDVDDPELAVQPAYTPLTRLS 1251 Query: 180 PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWE 239 DD+AY+ YTSGTTGVPK VA+ H NV +L+ L DL GQVWSQ HSL FD SVWE Sbjct: 1252 ADDIAYLIYTSGTTGVPKGVAIPHKNVGRLLHVLGGDLELSAGQVWSQSHSLAFDFSVWE 1311 Query: 240 IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLS------PE---- 289 I+GALLHGGRLV+VPE+V SP++ H LL+ E+VSVL QTPSA L PE Sbjct: 1312 IFGALLHGGRLVIVPETVVRSPEEFHALLVDEQVSVLSQTPSAFYALQTVDAMVPERAGQ 1371 Query: 290 -GLESTTLIVAGEACPTELVDRWAPGRV----MINAYGPTEATIYAAMSEPLXXXXXXXX 344 G+E ++ GEA + + W ++N YG TE T++A+ E + Sbjct: 1372 LGIE--VVVFGGEALEPQRLKPWMERHPVLPRLVNMYGITETTVHASFREIVSADTEVTV 1429 Query: 345 XXXXXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPF--G 400 + FVLD+ LRP P GVVGELYV G G+ GY+GR LTA+RFVACPF G Sbjct: 1430 SPIGSPLAHVGFFVLDRSLRPVPAGVVGELYVVGAGLGYGYVGRAGLTAARFVACPFRVG 1489 Query: 401 ETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIA 460 +G+RMYRTGDL WG GQL+Y GRADEQVKIRG+RIELGEI +AL GV+QA VIA Sbjct: 1490 ASGQRMYRTGDLASWGPGGQLQYAGRADEQVKIRGHRIELGEIHSALTAAPGVEQAAVIA 1549 Query: 461 REDRPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALP 520 REDRPGDKRLVGY+TGTAD A++R LAE LP+YMVP AVV L +PLTVNGKLD++ALP Sbjct: 1550 REDRPGDKRLVGYVTGTADTARIRAQLAECLPSYMVPAAVVSLAALPLTVNGKLDKKALP 1609 Query: 521 APEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA 580 APEY S + YRAP+T E+ILA +YAQVLG+ERVGVDDSFFDLGGDSI ++QVV RA Sbjct: 1610 APEY-SDIDHYRAPATLVEEILAGIYAQVLGLERVGVDDSFFDLGGDSISAIQVVWRAHG 1668 Query: 581 AGIQCRPRDIFVEQTXXXXXXXXXXXXESH-VVDEGVGPVVATPIMRWLREVDGPTGQFN 639 AG+ RPRDIFV+QT S V+DEGVG +VATPIM WL+ ++GP +FN Sbjct: 1669 AGLIGRPRDIFVQQTVARLARVVRMADGSDGVIDEGVGSMVATPIMLWLKGIEGPIDEFN 1728 Query: 640 QTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECL 699 QTV+ QAPAGVTE V+++LQALLDRH+ LRLR D + W+L VPE G V A +CL Sbjct: 1729 QTVVLQAPAGVTEAAVLIMLQALLDRHSMLRLRAAD--DGAGGWALTVPEPGTVNAADCL 1786 Query: 700 RTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNI 759 VD L+D+ LV AR+RLDPAAG M+S +WV T QLVL+IHHLAVDGVSWRILLEDL I Sbjct: 1787 HAVDVLSDETLVAARSRLDPAAGVMLSGLWVAATGQLVLIIHHLAVDGVSWRILLEDLTI 1846 Query: 760 AWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDT 819 A Q GQ + LP GTSF RWS LAEHA+ V A AWR V S+ +L +P Sbjct: 1847 ASTQLRGGQQVLLPPAGTSFQRWSDRLAEHARHPDVVRQAGAWRQVGSIASSLAAPRPTE 1906 Query: 820 DTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDV 879 DT+ TAG+L+ LD ETT LLGEVPAAF AGV +ILL+AF LAW + L PI +DV Sbjct: 1907 DTFATAGRLTEFLDAETTHMLLGEVPAAFHAGVHEILLIAFALAWAQHLGTGAAPIAIDV 1966 Query: 880 EGHGRYDELAS-------DVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKA 932 EGHGR+++L + ++DLSRTVGWFTTKYPV+L V L W QVVAGDAALG ++K Sbjct: 1967 EGHGRHEDLPARSGTSEGNIDLSRTVGWFTTKYPVSLAVGGLRWTQVVAGDAALGAVIKE 2026 Query: 933 VKEQLRSLPEGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXX 992 KEQLR++P+GLTYGLLRYLNP+VDL SDP IGFNYLGRLG+ A S ++WR Q Sbjct: 2027 AKEQLRAMPDGLTYGLLRYLNPDVDLPESDPAIGFNYLGRLGSPAAYASGDVWRFSQEGL 2086 Query: 993 XXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALA 1052 +P+ L HTVELNA TIDTD GP L A+WTWAP+A D TR++RLWF+ALA Sbjct: 2087 SLTGAAGAMPIALPHTVELNAVTIDTDTGPHLNATWTWAPTALDRMAVTRINRLWFDALA 2146 Query: 1053 GICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGI 1112 GICAHVR GGGGLTPSD+ PARL+Q+QID L + V DVLPLTP+QQGLLFH+ A+ Sbjct: 2147 GICAHVRRGGGGLTPSDILPARLSQQQIDGLQSHFPVADVLPLTPLQQGLLFHAGIAKSS 2206 Query: 1113 GDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWR 1172 GDDVYAVQ +I + GVLD RL +AV TVVARHP+LAARF +QF +P+Q++ A P+ W Sbjct: 2207 GDDVYAVQFEIALGGVLDAERLHEAVQTVVARHPHLAARFCDQFEQPLQIIPAQPVAPWM 2266 Query: 1173 YLDLRGD--DLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVI 1230 Y++L D + +IE++CAAER+AVCDL E+P FRA LIR + N++RFVLT HHIV+ Sbjct: 2267 YIELADGIADSDTEEQIEKICAAERTAVCDLAEQPAFRAVLIRVADNRYRFVLTNHHIVL 2326 Query: 1231 DGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVA 1290 DGWS+PIL+QEIFAGY G RLP AA YR+FV WL WR+ + GF+ PTL+ Sbjct: 2327 DGWSMPILMQEIFAGYHGVRLPPAASYRSFVTWLSERDQVAAQHAWRKAMAGFDAPTLLG 2386 Query: 1291 PPGVP--GPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFG 1348 PP G R ++ +RV TTRAL +LARSQ TT+N VLQ AW LL + G DVAFG Sbjct: 2387 PPQKLQFGRRSVDLFRVPLRTTRALTKLARSQQTTVNVVLQGAWALLLSSLCGHGDVAFG 2446 Query: 1349 TAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALND 1408 T VSGRPA++ GAESMVGLLINTVP+RA + A TT +LL QLQ HNDTLEH+HLAL+D Sbjct: 2447 TTVSGRPAEVLGAESMVGLLINTVPVRATIGAATTTAELLGQLQGRHNDTLEHQHLALSD 2506 Query: 1409 IHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGL 1468 IH ++G E+LFDT+F+YE+YP DT A V LA+T ++R+Y HYP++V A PG EL L Sbjct: 2507 IHRITGQERLFDTVFVYENYPTDTRAAADVNGLAITGLSSRDYYHYPIAVQAGPGRELEL 2566 Query: 1469 RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRA--V 1526 RV+YDT VFD I+ LI+RF+++L AM P R+LSS+D+++ R D W+ R+ V Sbjct: 2567 RVQYDTDVFDAESIKELIERFKQVLVAMTAHPGRQLSSLDLLNGIGR---DRWSERSSRV 2623 Query: 1527 LTQPVDS 1533 Q VD+ Sbjct: 2624 EGQSVDT 2630 Score = 698 bits (1802), Expect = 0.0 Identities = 444/1016 (43%), Positives = 583/1016 (57%), Gaps = 70/1016 (6%) Query: 1092 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAAR 1151 V+PL+ Q L F VY + + + + GVLD L A V+ RH +L Sbjct: 637 VMPLSYAQSRLWFIDQLHGP--SPVYNLAVGLRLQGVLDADALEAAFTDVLDRHESLRTM 694 Query: 1152 FVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAAL 1211 F G P Q++ + + + + D D + + + + E P F+A L Sbjct: 695 FPAVDGIPQQLIVPVEHVEFGWEVIDACDWQTDRLDSAVAESAQHSFVLSSEIP-FKARL 753 Query: 1212 IRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH-------RLPAAAPYRNFVNWL 1264 R + + H V HHI DGWS+ L+ ++ Y R P A Y ++ W Sbjct: 754 FRVAADDHVLVAVVHHIAADGWSITPLVADLGVAYASRCAGQAPDRKPLAVQYADYTLWQ 813 Query: 1265 XXXXXXXXXXX---------WREVLDGFETPTLVAPPGVPGPRGIESY--RVS----AET 1309 W +L G L P P P + RV AE Sbjct: 814 RAQLGDLDDSESRIARQLTYWENMLAGMPE-RLALPTDRPYPLVADQSGSRVDVAWPAEL 872 Query: 1310 TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVGL 1367 + + LAR + T V+QAA + +++ DVA G ++GR PA + ++G Sbjct: 873 QQRVNGLAREHNATSFMVMQAALAVVFSKLSASSDVAIGFPIAGRRDPA----LDELIGF 928 Query: 1368 LINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLA-------LNDIHHVSGHEQLFD 1420 +NT+ +R ++ D +V +LL Q+++ E++ + LN ++ H L Sbjct: 929 FVNTLVLRVDLAGDPSVAELLAQVRARSLGAFENQDVPFELLVERLNPARSLT-HHPLVQ 987 Query: 1421 TLFLYESYP---IDTSAFMGVQELAVTEFNNREYNHYPLSVMALP------GHELGLR-- 1469 +F +++ P D+ M + +L +T+ ++ +L G G+ Sbjct: 988 VMFAWQNIPGQIDDSGREMALADLELTQLPLDTHSARMDLAFSLAESWTEAGEAAGISGT 1047 Query: 1470 VEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQ 1529 VE+ T VFD +E LIDR +R+L+ M D AR LS++DV+D +E +LDEW NRA L Q Sbjct: 1048 VEFRTDVFDARSVEILIDRLRRVLDTMTADSARPLSAIDVLDAEELARLDEWGNRAELAQ 1107 Query: 1530 PVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVA 1589 PV S SIP +FA+QV R P A AV+ G L+Y ELDEA+N+LA+ L YGA PG+ VA Sbjct: 1108 PVTSV-SIPALFAQQVSRVPGAVAVSSAGGHLSYQELDEASNRLAHKLIEYGAGPGERVA 1166 Query: 1590 LMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGF 1649 L+ RSA+AIVAI+ VLKTGAAY+P+DPSVP ARLEF+L DA+P AVTT DL R D Sbjct: 1167 LLFARSAEAIVAIMGVLKTGAAYVPVDPSVPDARLEFVLADAEPAVAVTTSDLMDRLDAC 1226 Query: 1650 DLQVVEVDDPAVEIYPSTTLLTP-SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLP 1708 + V++VDDP + + P+ T LT S DDIAY+IYTSGTTGVPKGVAI H NV ++L L Sbjct: 1227 GVVVIDVDDPELAVQPAYTPLTRLSADDIAYLIYTSGTTGVPKGVAIPHKNVGRLLHVLG 1286 Query: 1709 AELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVN 1768 +L G VWSQ HSL FD SVWEI+GALLHGGRLVIVPE++ SP++ HALLV E V+ Sbjct: 1287 GDLELSAGQVWSQSHSLAFDFSVWEIFGALLHGGRLVIVPETVVRSPEEFHALLVDEQVS 1346 Query: 1769 VLYQTPSA------VRMMSPE--GLEGTALVV-AGEACPTEVVDRWA----VDRVMINAY 1815 VL QTPSA V M PE G G +VV GEA + + W V ++N Y Sbjct: 1347 VLSQTPSAFYALQTVDAMVPERAGQLGIEVVVFGGEALEPQRLKPWMERHPVLPRLVNMY 1406 Query: 1816 GPTESTIYAAISAPLSPGSDVV--PIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXX 1873 G TE+T++A+ +S ++V PIGSP+ FVLD LRPVP GVVGELY+ Sbjct: 1407 GITETTVHASFREIVSADTEVTVSPIGSPLAHVGFFVLDRSLRPVPAGVVGELYVVGAGL 1466 Query: 1874 XXXXXXXXXLTGTRFVACPF--GEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYR 1931 LT RFVACPF G G RMYRTGDL WG GQLQY GRADEQVKIRG+R Sbjct: 1467 GYGYVGRAGLTAARFVACPFRVGASGQRMYRTGDLASWGPGGQLQYAGRADEQVKIRGHR 1526 Query: 1932 IELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVP 1991 IELGEI +AL+ GV+QA VIAREDRPGDKRLVGY+TGTAD A R++L LP+YMVP Sbjct: 1527 IELGEIHSALTAAPGVEQAAVIAREDRPGDKRLVGYVTGTADTARIRAQLAECLPSYMVP 1586 Query: 1992 AAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVER 2047 AAVV+L LPLTVNGKLD++ALPAPEY YRAP T E+ LAGI+A VLG+ER Sbjct: 1587 AAVVSLAALPLTVNGKLDKKALPAPEYSDIDHYRAPATLVEEILAGIYAQVLGLER 1642 Score = 646 bits (1667), Expect = 0.0 Identities = 416/972 (42%), Positives = 552/972 (56%), Gaps = 66/972 (6%) Query: 6 STRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDR 65 +TR LLS DL D+DE + E WGNRA L P+ ++IP LFAEQVVR P AVA+ G R Sbjct: 5 ATRRLLSMDLDDDDERAEWEEWGNRAALERSAPS-LSIPELFAEQVVRDPGAVAVSCGGR 63 Query: 66 SWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAH 125 S +YR LDEASNRLAH+L HG PG VA L+ RS EA+++I+ VLKTGAAY+P+DP+ Sbjct: 64 SVSYRGLDEASNRLAHLLISHGVGPGQRVALLLSRSVEAVVAIMGVLKTGAAYVPIDPSV 123 Query: 126 PDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMAD----PAIDRRPSDALSGPRPD 181 PDAR+ F++ DA PV +TTA+L RL L +ID+ D P + LS P Sbjct: 124 PDARLRFVLCDAGPVVVVTTAELADRLGGSGLVIIDIDDVSSGPGAAQTDGPQLSAPCGS 183 Query: 182 DLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIW 241 D+AY+ YTSGTTG PK VA+ HHNVT+L+ A+ ADL PGQ W+Q HSL FD SVWEI+ Sbjct: 184 DIAYVIYTSGTTGTPKGVAIPHHNVTRLLEAIDADLELVPGQGWAQCHSLAFDFSVWEIF 243 Query: 242 GALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSA--------AGMLSPEGLES 293 GALLHGGRLVVV +SV +PD L LLI E++ VL QTPSA A L Sbjct: 244 GALLHGGRLVVVSDSVVRTPDRLRALLIDERIGVLSQTPSAFYALLAADADRSQDARLGL 303 Query: 294 TTLIVAGEACPTELVDRWAPGRV----MINAYGPTEATIYAAMSEPLXXXXXXXXXXXXX 349 ++ GEA + W +IN YG TE T++A+ E Sbjct: 304 DVVVFGGEALEPARLSDWFQDHPQSPRLINMYGITETTVHASFREITVADVVGTSSPIGV 363 Query: 350 XXXXLF--VLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMY 407 L VLD+WL+P VVGELYVAG G+ GY+GR L A+RFVACP+G G RMY Sbjct: 364 PLGHLAFSVLDEWLQPVSVDVVGELYVAGSGLGYGYVGRAPLNATRFVACPWGGPGTRMY 423 Query: 408 RTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGD 467 RTGDLV WG+DGQL YLGRADEQVKIRG+RIELGEI++ L L+GV QAVVIAREDRPGD Sbjct: 424 RTGDLVSWGTDGQLRYLGRADEQVKIRGHRIELGEIRSVLNGLNGVGQAVVIAREDRPGD 483 Query: 468 KRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSA 527 KRLVGY TGTADPA+LR AL + LP+YMVP +V L +PLTVNGKLD ALPAPEY+S Sbjct: 484 KRLVGYFTGTADPAELRAALTDRLPSYMVPVVLVALPRLPLTVNGKLDLDALPAPEYQS- 542 Query: 528 ANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVA---RARAAGIQ 584 + YRAP++P+E+ILA +YAQVLG++RVG+DDSFFDLGGDS+L+M++VA R+ AG++ Sbjct: 543 VDQYRAPTSPSEEILAGIYAQVLGLDRVGMDDSFFDLGGDSLLAMRLVAALNRSMDAGLE 602 Query: 585 CRPRDIFVEQTXXXXXXXXXXXXES-HVVDEGVGPVV-----ATPIMRWLREVDGPTGQF 638 R +F T + + G P V A + ++ ++ GP+ + Sbjct: 603 --ERAVFDAPTVAQLMLRIGGGEHTLEPLIAGERPAVMPLSYAQSRLWFIDQLHGPSPVY 660 Query: 639 NQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVP----EAGAVG 694 N V + + D + +LDRH +LR D L+VP E G Sbjct: 661 NLAVGLRLQGVLDADALEAAFTDVLDRHESLRTMFPAV--DGIPQQLIVPVEHVEFGWEV 718 Query: 695 ARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWR 751 C D L V A++ ++ A R + LV ++HH+A DG S Sbjct: 719 IDACDWQTDRLDSAVAESAQHSFVLSSEIPFKARLFRVAADDHVLVAVVHHIAADGWSIT 778 Query: 752 ILLEDLNIAWAQHCTGQSIELPAGGTSFARWS----ALLA--EHAKTDTVRDLADAWRAV 805 L+ DL +A+A C GQ+ + +A ++ A L + +++ R L + Sbjct: 779 PLVADLGVAYASRCAGQAPDRKPLAVQYADYTLWQRAQLGDLDDSESRIARQLTYWENML 838 Query: 806 TSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFR---AGVQDILLVAFGL 862 +P+ L + D + A Q + +DV +L V R A ++ A + Sbjct: 839 AGMPERL-ALPTDRPYPLVADQSGSRVDVAWPAELQQRVNGLAREHNATSFMVMQAALAV 897 Query: 863 AWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAG 922 +++ SD IG + G D L +G+F V L +AG Sbjct: 898 VFSKLSASSDVAIGFPIAGR-------RDPALDELIGFF---------VNTLVLRVDLAG 941 Query: 923 DAALGGIVKAVK 934 D ++ ++ V+ Sbjct: 942 DPSVAELLAQVR 953 Score = 604 bits (1558), Expect = e-170 Identities = 342/634 (53%), Positives = 421/634 (66%), Gaps = 31/634 (4%) Query: 1499 DPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEG 1558 D RRL SMD+ DDDER + +EW NRA L + S SIPE+FA QV RDP A AV+ G Sbjct: 4 DATRRLLSMDLDDDDERAEWEEWGNRAALERSAPS-LSIPELFAEQVVRDPGAVAVSCGG 62 Query: 1559 ESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPS 1618 S++Y LDEA+N+LA+LL +G PG+ VAL++ RS +A+VAI+ VLKTGAAY+PIDPS Sbjct: 63 RSVSYRGLDEASNRLAHLLISHGVGPGQRVALLLSRSVEAVVAIMGVLKTGAAYVPIDPS 122 Query: 1619 VPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDD----PAVEIYPSTTLLTPSP 1674 VP ARL F+L DA PV VTT +L R G L ++++DD P L P Sbjct: 123 VPDARLRFVLCDAGPVVVVTTAELADRLGGSGLVIIDIDDVSSGPGAAQTDGPQLSAPCG 182 Query: 1675 DDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEI 1734 DIAY+IYTSGTTG PKGVAI H NVT++L+ + A+L PG W+Q HSL FD SVWEI Sbjct: 183 SDIAYVIYTSGTTGTPKGVAIPHHNVTRLLEAIDADLELVPGQGWAQCHSLAFDFSVWEI 242 Query: 1735 WGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMM-------SPEGLEG 1787 +GALLHGGRLV+V +S+ +PD L ALL+ E + VL QTPSA + S + G Sbjct: 243 FGALLHGGRLVVVSDSVVRTPDRLRALLIDERIGVLSQTPSAFYALLAADADRSQDARLG 302 Query: 1788 TALVV-AGEACPTEVVDRWAVDRV----MINAYGPTESTIYAAISAPLSPGSDVV----P 1838 +VV GEA + W D +IN YG TE+T++A+ +DVV P Sbjct: 303 LDVVVFGGEALEPARLSDWFQDHPQSPRLINMYGITETTVHASFREITV--ADVVGTSSP 360 Query: 1839 IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGA 1898 IG P+ A VLDEWL+PV VVGELY+A L TRFVACP+G PG Sbjct: 361 IGVPLGHLAFSVLDEWLQPVSVDVVGELYVAGSGLGYGYVGRAPLNATRFVACPWGGPGT 420 Query: 1899 RMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDR 1958 RMYRTGDLV WG DGQL+YLGRADEQVKIRG+RIELGEI++ L+ ++GV QAVVIAREDR Sbjct: 421 RMYRTGDLVSWGTDGQLRYLGRADEQVKIRGHRIELGEIRSVLNGLNGVGQAVVIAREDR 480 Query: 1959 PGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY 2018 PGDKRLVGY TGTADPA R+ LT+RLP+YMVP +V L LPLTVNGKLD ALPAPEY Sbjct: 481 PGDKRLVGYFTGTADPAELRAALTDRLPSYMVPVVLVALPRLPLTVNGKLDLDALPAPEY 540 Query: 2019 QSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDAD 2078 QS +YRAP + +E+ LAGI+A VLG++R AMR+ AA+N ++DA Sbjct: 541 QSVDQYRAPTSPSEEILAGIYAQVLGLDRVGMDDSFFDLGGDSLLAMRLVAALNRSMDAG 600 Query: 2079 LSVRTLFEAPTVAKLSLHV---EHD-----AGER 2104 L R +F+APTVA+L L + EH AGER Sbjct: 601 LEERAVFDAPTVAQLMLRIGGGEHTLEPLIAGER 634 Score = 63.2 bits (152), Expect = 5e-07 Identities = 31/57 (54%), Positives = 42/57 (73%) Query: 525 RSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA 581 R + Y P+T EQIL+ ++A VLGV+RVGVD+SFFDLGG+S+ +M+VVA A Sbjct: 2631 RDTNSTYCRPATLNEQILSSIFAHVLGVDRVGVDESFFDLGGNSLGAMRVVAAINTA 2687 Score = 62.4 bits (150), Expect = 9e-07 Identities = 34/75 (45%), Positives = 45/75 (60%) Query: 2024 YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRT 2083 Y P T E+ L+ IFAHVLGV+R AMRV AA+NTAL+A+L++ Sbjct: 2637 YCRPATLNEQILSSIFAHVLGVDRVGVDESFFDLGGNSLGAMRVVAAINTALNANLTMLA 2696 Query: 2084 LFEAPTVAKLSLHVE 2098 LF+APTV L+ +E Sbjct: 2697 LFDAPTVRNLAQQLE 2711 >tr|D6A934|D6A934_9ACTO Tax_Id=566461 SubName: Full=Amino acid adenylation;[Streptomyces ghanaensis ATCC 14672] Length = 3940 Score = 1363 bits (3527), Expect = 0.0 Identities = 882/2107 (41%), Positives = 1154/2107 (54%), Gaps = 146/2107 (6%) Query: 42 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRS 101 T P LF+ +V APDA A++ GDR TY ELDE ++RLA VLA G P VA +PRS Sbjct: 1316 TFPQLFSARVAAAPDAPAVLFGDRVLTYGELDERTDRLAAVLAGRGVGPERIVAVAVPRS 1375 Query: 102 GEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADL---------RSRL 152 E ++ +L+VLK GAAYLPVD +P R+ +M+ D++P +TT+ + R + Sbjct: 1376 AELVVCVLAVLKAGAAYLPVDLDYPADRVAYMLRDSRPALVITTSAVADTIPGDVPRLLV 1435 Query: 153 DQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSA 212 D+ D D+A P P+ S AY+ YTSG+TG PK V V+H V L +A Sbjct: 1436 DRPD----DLAGPVAPVVPAGVASP------AYVIYTSGSTGRPKGVVVSHAGVGNLATA 1485 Query: 213 LHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEK 272 Q+ S FD SV E++ L LV DL + + Sbjct: 1486 QIDRFALTDAGRLLQFASPSFDASVSEVFTTWLSSATLVTATADHLRPGTDLADTVRDLH 1545 Query: 273 VSVLCQTPSAAGMLSPEGLES-TTLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAA 331 ++ P+A + P L TTL+VAGEA P ++V+ WAPGR MINAYGPTE T+ A Sbjct: 1546 ITHATIPPAALAAMEPSDLPGLTTLVVAGEAVPAQVVEAWAPGRRMINAYGPTETTVCAT 1605 Query: 332 MSEPLXXXXXXXXXXXXXXXXX-LFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLT 390 MS PL ++VLD+ LRP GVVGELYVAG G+A GY+ RPDLT Sbjct: 1606 MSTPLTGPQPDSVPIGTPITNTRVYVLDETLRPVAPGVVGELYVAGTGLARGYLNRPDLT 1665 Query: 391 ASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKL 450 A RFVACPFG GERMYRTGDLVRW DG+L YLGR D+QVK+RG+RIELGE++ AL L Sbjct: 1666 AERFVACPFGSPGERMYRTGDLVRWTEDGELTYLGRTDDQVKLRGFRIELGEVETALRHL 1725 Query: 451 DGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTI 506 DG+ QA + REDRPGD+RL+ Y TADPA LR AL +LP +MVP A+V LD + Sbjct: 1726 DGIRQAAAVIREDRPGDRRLIAYTVHDTDHTADPAALRDALRTTLPEHMVPAAIVPLDAL 1785 Query: 507 PLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGG 566 PLTV+GKLDR ALPAP Y AA RAPS P E L ++A VLGVE VGVDD FFDLGG Sbjct: 1786 PLTVHGKLDRTALPAPAYGRAAGVGRAPSGPVETTLCAIFADVLGVETVGVDDGFFDLGG 1845 Query: 567 DSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVV---DEGVGPVVATP 623 DSI+S+Q+VARAR AG+ RD+F +T +H D G+GPV TP Sbjct: 1846 DSIVSIQLVARARKAGLALTARDVFQHKT-VAALAEVAEAATAHTAEDPDAGIGPVDTTP 1904 Query: 624 IMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEW 683 I+ WL E+ GPT +F+Q+++ Q PAG + + LQALLDRH LR R+ D W Sbjct: 1905 IVAWLSELGGPTDRFSQSMLLQIPAGTRREQLTEALQALLDRHDALRSRL---HRRADGW 1961 Query: 684 SLLVPEAGAVGARECLRTVDA--LTDDVLVEARNR--------LDPAAGAMVSAVWV--- 730 SL V AV A + + DA +T L +A R L P G M+ AVW Sbjct: 1962 SLEVLPRDAVRAADLILRADAHGVTGAGLRQAVTRHHDMAQAALAPEDGVMLRAVWFDAG 2021 Query: 731 -RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEH 789 +L+L+ HHL VDGVSWRILL DL A A G+ IEL TS W+ L H Sbjct: 2022 DEAPGRLLLVAHHLVVDGVSWRILLTDLAAAGAAVAAGRRIELDPVPTSLRTWARELTAH 2081 Query: 790 AKTDTVRDLADAWRAVTSVPQAL---PPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPA 846 D +L W + P L PV P DT T LS SL T LLGEV Sbjct: 2082 T-ADRTGEL-PFWERTLAGPDPLLGDRPVDPARDTMGTTRSLSVSLPAPVTSALLGEVTR 2139 Query: 847 AFRAGVQDILLVAFGLA---WTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTT 903 F A ++LL LA W + +D+EGHGR D LA VD+SRTVGWFT+ Sbjct: 2140 VFHARANEVLLAGLALAVPKWRRARGLDGDDVLLDLEGHGREDVLAG-VDVSRTVGWFTS 2198 Query: 904 KYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNP---EVDLG 959 +PV L AG + VK VKEQ+R++P+ G+ YGLLR+L+P + Sbjct: 2199 LFPVRLN----------AGADGVDTAVKRVKEQVRAVPDNGIGYGLLRHLDPGARPLLAA 2248 Query: 960 GSDPTIGFNYLGRLGAGAGELSEELWR-IDQXXXXXXXXXXXVPMPLMHTVELNAGTID- 1017 P IGFNYLGR+ GAG W + M + H +E++A D Sbjct: 2249 LPVPQIGFNYLGRMDGGAGPAD---WAPAAESDLLLGTGVADAAMAVPHPLEISAVVRDG 2305 Query: 1018 TDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVR-GGGGGLTPSDVAPARLT 1076 D GP L +W WA DE LS WF+AL I AH G GG TP+D+ RL+ Sbjct: 2306 QDEGPVLTVTWVWAEGLLDEAAVRALSAAWFDALRDIAAHAALPGAGGFTPADLPLVRLS 2365 Query: 1077 QRQIDELSQRYDV-TDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLR 1135 Q QID + + + +D+LP+ P+Q+GLLFH+ F G G DVY+VQ + G LD LR Sbjct: 2366 QEQIDRIEETHPAPSDILPVAPLQEGLLFHAMFDEG-GPDVYSVQFSFGLDGPLDAGALR 2424 Query: 1136 DAVHTVVARHPNLAARF-VEQFGEPVQVLTADPMIAWRYLDLRG-DDLTPDHEIEQLCAA 1193 A +++ARH NL A F ++ PVQV+ A + WR +DL G D+ +E++ A Sbjct: 2425 AAAESLLARHDNLRAAFRLDVADRPVQVIPATVDLPWREVDLSGLDEAAQRAGVERVLAE 2484 Query: 1194 ERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGY-----FG 1248 +R+A DL P R L++ +G +HR V HH+++DGWS+PI+ E+F Y Sbjct: 2485 DRAARYDLSVAPLLRFTLVKLAGERHRLVFANHHVLLDGWSMPIVFGELFTLYARNVGAD 2544 Query: 1249 HRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIE------- 1301 LP PYR+++ W+ WR LDG E PTL+ P G RG + Sbjct: 2545 RDLPRVTPYRDYLAWVGEQDRAVALDAWRSALDGVEEPTLLVPDD-SGARGADHGAEVPR 2603 Query: 1302 --SYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLA 1359 + + AE T +L E AR T+NTV+Q W LL R+TG+ DV FG VSGRP ++ Sbjct: 2604 QLPFELPAELTASLQEWARRSGLTLNTVVQGLWAVLLGRLTGRDDVVFGATVSGRPPEVP 2663 Query: 1360 GAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLF 1419 G ESMVGL INTVP+R V TV LL ++Q+ + + H+H+ L++I + G LF Sbjct: 2664 GIESMVGLFINTVPVRITVDPAETVTALLTRVQAAQSALMPHQHVQLSEIQGLVGIGDLF 2723 Query: 1420 DTLFLYESYPIDTSAF-MGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFD 1478 DTL ++ESYP+D + + L V++ + + HYP+++ ALPG L LR+EY F Sbjct: 2724 DTLTVFESYPMDAAVLELPGTGLRVSDVDGADATHYPVTLAALPGDRLRLRLEYAPGRFP 2783 Query: 1479 VSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIP 1538 + L R L EA+ +DP R + +DV+ ER N + P Q++ Sbjct: 2784 QDRAQALAARLTGLFEAVAEDPDRPVGRLDVLTAQERETALTGGNALLHPVPGHPVQALL 2843 Query: 1539 EVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADA 1598 E A R P+A AV F G +L EL+E AN+LA LL GA P + VAL +PR A Sbjct: 2844 EDLA---ARTPDATAVVFRGTTLTCSELNERANRLARLLIARGAGPERIVALALPRGPQA 2900 Query: 1599 IVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVT--TGDLRSRFDGFDLQV--- 1653 +VA+ AVLK GAA+L +DP PA R+ ++L DA P +T GD +G + Sbjct: 2901 LVAMFAVLKAGAAFLTVDPEFPADRIAYLLRDAAPTVVLTDREGDAHWTAEGLGAGIGRL 2960 Query: 1654 ----------VEVDDPA-VEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQ 1702 + DPA V T LTP+ AY+IYTSG+TG PKGV + H N+ Sbjct: 2961 VLDAEETGRELAAADPADVVDTDRTAPLTPAAP--AYVIYTSGSTGRPKGVVVQHHNLVN 3018 Query: 1703 VL----DTL-----PAELPAGPGAVWSQWHSLVFDVSVWE--IWGALLHGGRLVIVPESI 1751 + +TL A+ P G V + FD + W+ +W +L G L ++ + Sbjct: 3019 LFHGHKETLFDRHARADDPDGRFRV-ALTAVFSFD-TAWDGVLW--MLDGHELHLIDDDT 3074 Query: 1752 AGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL------EGTALVVAGEACPTEVVDRW 1805 P+ L A + E V+ L TP+ + GL L++ GEA ++ R Sbjct: 3075 RRDPEALAAYVDRERVDFLDLTPAFAGQLVEAGLLADGRHHPAVLMLGGEALGPDLWSRL 3134 Query: 1806 --AVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVV 1863 A N YGPTE+TI + PL+ S+ +G PV VLD LRPVPPGV Sbjct: 3135 RAAPRTTAYNFYGPTEATI-DTVFLPLAE-SEKPLVGRPVRNTRVHVLDGHLRPVPPGVT 3192 Query: 1864 GELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADE 1923 GELYLA LT FVA PFGEPG+R+YRTGDLVR DG L+Y GR D+ Sbjct: 3193 GELYLAGDQLARGYLGRPDLTAGSFVANPFGEPGSRLYRTGDLVRATADGLLEYRGRTDD 3252 Query: 1924 QVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAAARS 1979 QVK+RG+RIELGEI++AL+ V A V+ RED PG +RLVGY A +PAA R Sbjct: 3253 QVKVRGFRIELGEIESALAAGPDVAAAAVVVREDTPGVRRLVGYAVPAAGAAPEPAALRE 3312 Query: 1980 ELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGI 2038 + LP YMVPAAVV L+ LPLT NGKLDR ALPAP++ + A RA E+ L + Sbjct: 3313 RVGRTLPEYMVPAAVVLLDALPLTANGKLDRGALPAPDFSARATGGRAAGDPVEQALCAL 3372 Query: 2039 FAHVLGV 2045 FA VLG+ Sbjct: 3373 FADVLGL 3379 Score = 1291 bits (3341), Expect = 0.0 Identities = 805/1937 (41%), Positives = 1066/1937 (55%), Gaps = 94/1937 (4%) Query: 251 VVVPESVGSSPDDLHNLLITEKVSVLCQTPSAA-GMLSPEG--------LESTTLIVAGE 301 ++VP V SP+D LL +KV+VL QTPSA ++ EG L ++ GE Sbjct: 1 MIVPFEVSRSPEDFLALLADQKVTVLNQTPSAFYQLMRTEGDRPDLGARLALRYVVFGGE 60 Query: 302 ACPTELVDRW-------APGRVMINAYGPTEATIYA---AMSEPLXXXXXXXXXXXXXXX 351 A + W AP +IN YG TE T++ A+ Sbjct: 61 ALDLWRLQEWYGRHPEDAPR--LINMYGITETTVHVTHRALDRLTAKSATGSLIGRGIPD 118 Query: 352 XXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGD 411 + VLD LRPA GVVGE+YVAG G+A GY+GR LTA RFVA P+G G RMYRTGD Sbjct: 119 LGIRVLDSALRPAAPGVVGEMYVAGAGLARGYLGRHALTAERFVADPYGPPGTRMYRTGD 178 Query: 412 LVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLV 471 L RW DG+LEY+GRAD+QVKIRG+RIELGEI+A L V QA V+ REDRPGDKRLV Sbjct: 179 LARWDDDGELEYIGRADQQVKIRGFRIELGEIEACLETHADVVQAAVVVREDRPGDKRLV 238 Query: 472 GYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSA 527 GY DPA LR LA LP YMVP A V LD +PLT NGKLDR+ALPAP +A Sbjct: 239 GYTVLADGRHCDPAALRDHLAALLPDYMVPAAFVALDVLPLTSNGKLDRKALPAPVV-AA 297 Query: 528 ANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRP 587 RAP+T E+ L V+A+ LG+ VG DD+FFDLGGDSI+S+Q+++ AR AG++ Sbjct: 298 GTTGRAPATRTEETLCAVFAEALGLPAVGPDDNFFDLGGDSIVSLQMISLARRAGLRMTT 357 Query: 588 RDIFVEQTXXXXXXXXXXXXES--HVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQ 645 RD+F +T + V DE VGP+VATP++ WL G Q++Q + Q Sbjct: 358 RDVFKHRTPAALAAVAATGSAAAEPVRDEPVGPLVATPVVHWLAGRGGSMDQYHQATLVQ 417 Query: 646 APAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA- 704 PAG+ ++ + LQALL+RH LR+R T + W+L V AG+V AR+ LR V+ Sbjct: 418 VPAGLRQEHLTAALQALLERHDALRMRAVATGD--GGWTLEVAPAGSVEARDTLRRVEVP 475 Query: 705 ---------LTDDVLVEARNRLDPAAGAMVSAVWV----RETSQLVLMIHHLAVDGVSWR 751 L D+ A L P G M+ AVW +L+L+ HHL VDGVSW Sbjct: 476 DPAAGLPPELLDERTGAAVAELAPYDGVMLRAVWFDAGDEALGRLLLVAHHLVVDGVSWH 535 Query: 752 ILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQA 811 ILL DL AW G++ LP GTS W+ L A A+ W+ + S P Sbjct: 536 ILLSDLAEAWQAAADGRTPALPPYGTSLRTWARELHRLAHRPERVAEAELWQHLASGPDP 595 Query: 812 L---PPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA---WT 865 L V P+ DT T L+ SL T LLGEV FRA ++LL LA W Sbjct: 596 LLGSRAVDPERDTAATVRSLTVSLPPAETSALLGEVARVFRARAHEVLLAGLALAVPRWR 655 Query: 866 EFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAA 925 + + ++VEGHGR D L VD+SRTVGWFT+ +PV L AG Sbjct: 656 RARGVDTSEVLLEVEGHGREDVL-EGVDVSRTVGWFTSLFPVRLD----------AGGED 704 Query: 926 LGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEVD---LGGSDPTIGFNYLGRLGAGAGELS 981 G ++ VKEQ+R++P+ G+ +GLLR+L+P G P IGFNYLGR+G +G Sbjct: 705 AGEALRRVKEQMRAVPDNGIGFGLLRHLHPVAGAALAGLPTPQIGFNYLGRVGGPSGGDW 764 Query: 982 EELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQAT 1041 + MP+ HTV+LNA T +T GP L A W WA E + + Sbjct: 765 SPV-----AGERALTGADDPSMPVAHTVDLNAYTRETAKGPVLTAVWNWAGGLLTEAEVS 819 Query: 1042 RLSRLWFEALAGIC-AHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVT-DVLPLTPVQ 1099 L+ LWF AL + A + G GG TPSDV RLTQ QI + + T D+LP+TP+Q Sbjct: 820 GLADLWFRALRELVEASSQPGAGGFTPSDVPLVRLTQEQIRSIEAAHPATVDILPVTPLQ 879 Query: 1100 QGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF-VEQFGE 1158 QGLLFH+ F G G DVY VQ + G LD LR A ++ RHP L A F ++ Sbjct: 880 QGLLFHTLFDEG-GPDVYTVQFLYDLEGRLDAAALRGAAEEMLRRHPGLRAAFRLDGLDH 938 Query: 1159 PVQVLTADPMIAWRYLDLRGDDLTPDHEI-EQLCAAERSAVCDLLERPTFRAALIRTSGN 1217 VQV+ + W LDLR D T + +++ +R DL P R L+ + + Sbjct: 939 AVQVVPESVELPWTDLDLRHLDPTEQQTVLDRMLQEDRGNRFDLAAPPLMRFLLVALADD 998 Query: 1218 QHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWR 1277 +HR V T HH+++DGWS+P+ ++E+ Y G P+R+++ WL WR Sbjct: 999 RHRLVFTHHHVLLDGWSMPLFVRELLDLYAGRTPDRTPPHRDYLAWLAEQDASATASVWR 1058 Query: 1278 EVLDGFETPTLVAPPGVPGPRGIESYRVS----AETTRALGELARSQHTTINTVLQAAWT 1333 E L G + PTL+A P VP + + +++ A+ T L + AR+ T+NT+LQ AW+ Sbjct: 1059 EALQGLDEPTLLA-PSVPDRQPVVPDQLTADLPADLTARLQDTARAHGLTLNTLLQGAWS 1117 Query: 1334 QLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQS 1393 +L R+T + DV FG+ VSGRP + G ESMVGL INT+P+R ++ + L +LQ Sbjct: 1118 VVLSRLTARDDVVFGSTVSGRPPQVPGVESMVGLFINTLPVRVRIVPGESAVAFLTRLQD 1177 Query: 1394 HHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNH 1453 +EH+H+ L D+ ++G +LFDT+ + E+YP+D A + V LAVT + R+ H Sbjct: 1178 EQTRLMEHQHIGLADVQRIAGIGELFDTITVLENYPLD-PARLRVPGLAVTAIDGRDATH 1236 Query: 1454 YPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDD 1513 YPLS+ +PG L LR+ Y +FD + L+ RFQ +LE D P + +DV+ Sbjct: 1237 YPLSLAVMPGERLHLRINYRPDLFDADAVRQLVGRFQAVLEFWADRPQEPVGRIDVLPAA 1296 Query: 1514 ERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQL 1573 E L N P + P++F+ +V P+APAV F L YGELDE ++L Sbjct: 1297 EYEHLVRGVNGTARDVP---HATFPQLFSARVAAAPDAPAVLFGDRVLTYGELDERTDRL 1353 Query: 1574 ANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKP 1633 A +LA G P + VA+ VPRSA+ +V +LAVLK GAAYLP+D PA R+ +ML D++P Sbjct: 1354 AAVLAGRGVGPERIVAVAVPRSAELVVCVLAVLKAGAAYLPVDLDYPADRVAYMLRDSRP 1413 Query: 1634 VAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGV 1693 +TT + G D+ + VD P P ++ AY+IYTSG+TG PKGV Sbjct: 1414 ALVITTSAVADTIPG-DVPRLLVDRPDDLAGPVAPVVPAGVASPAYVIYTSGSTGRPKGV 1472 Query: 1694 AITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAG 1753 ++H V + Q+ S FD SV E++ L LV Sbjct: 1473 VVSHAGVGNLATAQIDRFALTDAGRLLQFASPSFDASVSEVFTTWLSSATLVTATADHLR 1532 Query: 1754 SPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG-TALVVAGEACPTEVVDRWAVDRVMI 1812 DL + + P+A+ M P L G T LVVAGEA P +VV+ WA R MI Sbjct: 1533 PGTDLADTVRDLHITHATIPPAALAAMEPSDLPGLTTLVVAGEAVPAQVVEAWAPGRRMI 1592 Query: 1813 NAYGPTESTIYAAISAPLS-PGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXX 1871 NAYGPTE+T+ A +S PL+ P D VPIG+P+ +VLDE LRPV PGVVGELY+A Sbjct: 1593 NAYGPTETTVCATMSTPLTGPQPDSVPIGTPITNTRVYVLDETLRPVAPGVVGELYVAGT 1652 Query: 1872 XXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYR 1931 LT RFVACPFG PG RMYRTGDLVRW +DG+L YLGR D+QVK+RG+R Sbjct: 1653 GLARGYLNRPDLTAERFVACPFGSPGERMYRTGDLVRWTEDGELTYLGRTDDQVKLRGFR 1712 Query: 1932 IELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTNRLPA 1987 IELGE++ AL +DG+ QA + REDRPGD+RL+ Y TADPAA R L LP Sbjct: 1713 IELGEVETALRHLDGIRQAAAVIREDRPGDRRLIAYTVHDTDHTADPAALRDALRTTLPE 1772 Query: 1988 YMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGIFAHVLGVE 2046 +MVPAA+V L+ LPLTV+GKLDR ALPAP Y ++A RAP E TL IFA VLGVE Sbjct: 1773 HMVPAAIVPLDALPLTVHGKLDRTALPAPAYGRAAGVGRAPSGPVETTLCAIFADVLGVE 1832 Query: 2047 RXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTD 2106 ++++ A A L+ R +F+ TVA L+ V A T Sbjct: 1833 TVGVDDGFFDLGGDSIVSIQLVARARKA-GLALTARDVFQHKTVAALA-EVAEAATAHTA 1890 Query: 2107 RVSFAAVHGSDVTEVHA 2123 A + D T + A Sbjct: 1891 EDPDAGIGPVDTTPIVA 1907 Score = 698 bits (1802), Expect = 0.0 Identities = 469/1158 (40%), Positives = 610/1158 (52%), Gaps = 96/1158 (8%) Query: 3 AEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVS 62 AE R + D+L E + GN + PG + AL + R PDA A+V Sbjct: 2802 AEDPDRPVGRLDVLTAQERETALTGGNALLHPVPGHP---VQALLEDLAARTPDATAVVF 2858 Query: 63 GDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVD 122 + T EL+E +NRLA +L GA P VA +PR +A++++ +VLK GAA+L VD Sbjct: 2859 RGTTLTCSELNERANRLARLLIARGAGPERIVALALPRGPQALVAMFAVLKAGAAFLTVD 2918 Query: 123 PAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLA------VIDM---------ADPAI 167 P P RI +++ DA P LT + + L V+D ADPA Sbjct: 2919 PEFPADRIAYLLRDAAPTVVLTDREGDAHWTAEGLGAGIGRLVLDAEETGRELAAADPA- 2977 Query: 168 DRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSA---------LHADLP 218 D +D + P AY+ YTSG+TG PK V V HHN+ L AD P Sbjct: 2978 DVVDTDRTAPLTPAAPAYVIYTSGSTGRPKGVVVQHHNLVNLFHGHKETLFDRHARADDP 3037 Query: 219 SGPGQVWSQWHSLVFDVSVWE--IWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVL 276 G +V + FD + W+ +W +L G L ++ + P+ L + E+V L Sbjct: 3038 DGRFRV-ALTAVFSFDTA-WDGVLW--MLDGHELHLIDDDTRRDPEALAAYVDRERVDFL 3093 Query: 277 CQTPSAAGMLSPEGL------ESTTLIVAGEACPTELVDRW--APGRVMINAYGPTEATI 328 TP+ AG L GL L++ GEA +L R AP N YGPTEATI Sbjct: 3094 DLTPAFAGQLVEAGLLADGRHHPAVLMLGGEALGPDLWSRLRAAPRTTAYNFYGPTEATI 3153 Query: 329 ------YAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATG 382 A +PL + VLD LRP P GV GELY+AG +A G Sbjct: 3154 DTVFLPLAESEKPLVGRPVRNTR--------VHVLDGHLRPVPPGVTGELYLAGDQLARG 3205 Query: 383 YIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGE 442 Y+GRPDLTA FVA PFGE G R+YRTGDLVR +DG LEY GR D+QVK+RG+RIELGE Sbjct: 3206 YLGRPDLTAGSFVANPFGEPGSRLYRTGDLVRATADGLLEYRGRTDDQVKVRGFRIELGE 3265 Query: 443 IQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAQLRTALAESLPAYMVPT 498 I++ALA V A V+ RED PG +RLVGY A +PA LR + +LP YMVP Sbjct: 3266 IESALAAGPDVAAAAVVVREDTPGVRRLVGYAVPAAGAAPEPAALRERVGRTLPEYMVPA 3325 Query: 499 AVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVD 558 AVV+LD +PLT NGKLDR ALPAP++ + A RA P EQ L ++A VLG+ VGVD Sbjct: 3326 AVVLLDALPLTANGKLDRGALPAPDFSARATGGRAAGDPVEQALCALFADVLGLPEVGVD 3385 Query: 559 DSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHV--VDEGV 616 SFFDLGGDSI+S+Q+VARARAAG+ P+D+F +T ++ D G+ Sbjct: 3386 SSFFDLGGDSIVSIQLVARARAAGLVFSPKDVFTHRTVAALAPVVRRAQDTPAEDPDAGI 3445 Query: 617 GPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDT 676 G + ATP++RWL+E G T F Q+++ + PAG+ + + +QALLD H LR+ V Sbjct: 3446 GTLPATPVIRWLQEHGGATDGFVQSMLVRVPAGLGLEHLTTAVQALLDHHDALRMTVTRG 3505 Query: 677 QEDTDEWSLLVPEAGAVGARECLRTV----------DALTDDVLVEARNRLDPAAGAMVS 726 +DT WSL VP G V A E + V +AL A LDPAAG M+ Sbjct: 3506 ADDT-PWSLEVPARGCVPAAEVVVRVPTGGFTGADLEALIAAEAEAAWRALDPAAGRMLR 3564 Query: 727 AVWV----RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARW 782 VW +L++ HHL VDGVSWRILL DL AW G GTSF RW Sbjct: 3565 VVWFDAGPSTPGRLLITAHHLVVDGVSWRILLPDLAAAWQAAAEGGQPRPAPNGTSFRRW 3624 Query: 783 SALLAEHAKTDTVRDLADAWRAVTS---VPQALPPVQPDTDTYVTAGQLSASLDVETTRQ 839 + L E A D + W + S P P+ P +DT A L+ SL + T Sbjct: 3625 AQRLTEAAAER--EDEVELWLEMLSEEEAPLGARPLAP-SDTAAGARSLTLSLPADRTEP 3681 Query: 840 LLGEVPAAFRAGVQDILLVAFGLAWTEFLNR----SDTPIGVDVEGHGRYDELASDVDLS 895 LL +VPAAF GV D+LL LA ++ R D + VD+EGHGR +++ DLS Sbjct: 3682 LLTDVPAAFHGGVNDVLLTGLALAVAQWRRRRGLGEDGAVLVDLEGHGR-EDVVGGADLS 3740 Query: 896 RTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNP 954 RTVGWFTT YPV L L ++V AG AALG VK VKEQLR++P+ G+ YG+LR+LNP Sbjct: 3741 RTVGWFTTVYPVRLDPGQLDRDEVRAGGAALGRAVKRVKEQLRAVPDHGIGYGMLRHLNP 3800 Query: 955 EVD---LGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVP-MPLMHTVE 1010 DP IGFNYLGRLGA E ++ W + P L H +E Sbjct: 3801 ATAPLLAEYPDPQIGFNYLGRLGAPGAE--DQDWAVAPESAALTGAAAGDPDTRLAHAIE 3858 Query: 1011 LNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRG-GGGGLTPSD 1069 +NA D GP L +WTW F E+ L+ WF+AL + + GG +PSD Sbjct: 3859 INALVRDLPGGPELNVTWTWPDGLFPEQDMQDLADNWFDALEALARYAAAPESGGHSPSD 3918 Query: 1070 VAPARLTQRQIDELSQRY 1087 + L+Q Q+D L + Sbjct: 3919 MPLVNLSQAQLDLLESTW 3936 >tr|C1AUS1|C1AUS1_RHOOB Tax_Id=632772 SubName: Full=Putative non-ribosomal peptide synthetase;[Rhodococcus opacus] Length = 8860 Score = 1360 bits (3519), Expect = 0.0 Identities = 856/2162 (39%), Positives = 1184/2162 (54%), Gaps = 111/2162 (5%) Query: 14 DLLDEDEHDQIEVWGNRAVLTDPGP--TPVTIPALFAEQVVRAPDAVALVSGDRSWTYRE 71 D+LD E + +R PG P+++ LF +AVA+ S TYRE Sbjct: 5398 DILDAPERGLVLTSAHR-----PGTDVAPLSLVDLFDRAAAAEAEAVAVRCEGSSVTYRE 5452 Query: 72 LDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIG 131 LDE +NRLA +L GA VA + RS + ++++++V+K+GA YLPVD P R+ Sbjct: 5453 LDERANRLARLLVARGAGAETLVAVGMTRSVDLVVALVAVVKSGAGYLPVDVDSPADRLA 5512 Query: 132 FMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPA----------IDRRPSDALSGPRPD 181 F++ DA+P LTT + V+ + DPA + D + D Sbjct: 5513 FLLGDARPGCVLTTTADAETFRGAGVPVVVVDDPATVTALQPLSPLPVTDDDRRTPLHLD 5572 Query: 182 DLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIW 241 +AY+ YTSG+TG PK V V+H NV LV+ GP VW+ +HS FD SVWE+W Sbjct: 5573 SVAYVIYTSGSTGQPKGVQVSHRNVVTLVANTQTLFGFGPADVWTMFHSAAFDFSVWEMW 5632 Query: 242 GALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPE-------GLEST 294 GAL HGGRLV V SP+ LL E V+V+ QTP+A L+ L Sbjct: 5633 GALAHGGRLVPVDYFTARSPEKFLELLRAEHVTVVNQTPTAFYQLAEADRLAGGPALSLR 5692 Query: 295 TLIVAGEACPTELVDRWAPGR-----VMINAYGPTEATIYAA---MSEPLXXXXXXXXXX 346 +I GEA + RW R V+ N YG TE T++ + L Sbjct: 5693 YVIFGGEALDFGQLRRWYARRGDTAPVLANMYGITETTVHVTHLPVDRDLAREASGSLIG 5752 Query: 347 XXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERM 406 ++VLD L P P GVVGE+YV G V+ GY+GRP LT+ RFVA PF G RM Sbjct: 5753 RGLPGLRVYVLDGRLHPVPPGVVGEMYVCGAQVSRGYLGRPALTSGRFVADPF-VPGARM 5811 Query: 407 YRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPG 466 YR+GDL RW + GQLEYLGR D QV+++GYRIELGE+++AL +GV QA V AR DR Sbjct: 5812 YRSGDLGRWNAHGQLEYLGRNDLQVQVKGYRIELGEVESALLASEGVAQAAVTARGDR-- 5869 Query: 467 DKRLVGYITGTA----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAP 522 LVGY+ A DPA + A AE L ++MVP AVVVL +PLTVNGKLDR+ALP P Sbjct: 5870 ---LVGYVVPEAGAAIDPAVVLDAAAERLASHMVPAAVVVLGGMPLTVNGKLDRKALPEP 5926 Query: 523 EYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAG 582 ++ R P T E+ILAD++A+VLG+ VGVDDSFF LGGDSI+S+Q+V RA+AAG Sbjct: 5927 DFGQRVTAGRGPVTETERILADLFAEVLGLGSVGVDDSFFALGGDSIMSIQLVTRAKAAG 5986 Query: 583 IQCRPRDIFVEQTXXXXXXXXXXXXESHVVDE----GVGPVVATPIMRWLREVDGPTGQF 638 + PRD+F +T + V+DE G+G + TPI+RW+ G ++ Sbjct: 5987 VLISPRDVFERKTVAALAATAGTDDAAVVLDELPGGGIGEIALTPIVRWMLARGGDFRRY 6046 Query: 639 NQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGAREC 698 Q+ + PAG+TED + +QA+LDRH LR R+ T WS+ GAV A Sbjct: 6047 AQSAVFTLPAGMTEDTLTQAVQAVLDRHDVLRARLSRTSRSEAGWSMEAAAEGAVRAATV 6106 Query: 699 LRTVDALTDDVLVE---ARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWRI 752 LR A DDV E A +RLDP +G MV AVW ++++++HHLA+DGVSWRI Sbjct: 6107 LRR--ARADDVGAEFDSALDRLDPESGVMVQAVWFGGGVRPPRVLIVVHHLAMDGVSWRI 6164 Query: 753 LLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQAL 812 L+ DL A AQ +G++ L GTS RW+ LA+ A+ D WR + P L Sbjct: 6165 LIPDLAAACAQLQSGRAPVLERPGTSMRRWAHGLADAAREPRRAAELDLWRTMLDAPDPL 6224 Query: 813 PPVQPDT--DTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNR 870 +P T DT TA ++ + T L VP AF GV D LL A +A T + R Sbjct: 6225 LGSRPLTAADTAATAADVAVRVPASLTETLSTTVPRAFHGGVADALLTALAMALTRWRRR 6284 Query: 871 SDTPIG---VDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALG 927 + V +EGHGR +++ DL+RT+GWFTT +PV L + + + AG + G Sbjct: 6285 RGIDVPGALVGLEGHGREEQVVPGADLARTIGWFTTIFPVRLELSGVDLDDAFAGGPSAG 6344 Query: 928 GIVKAVKEQLRSLPE-GLTYGLLRYLNPEVDLGGSD---PTIGFNYLGRLGAGAGELSEE 983 +K+VKEQL ++P+ G+ +GLLRYLN + S P + FNYLGR+GA A E +E Sbjct: 6345 TALKSVKEQLLAVPDHGIGFGLLRYLNDDTAQSLSALPMPQVSFNYLGRMGAAATETAEG 6404 Query: 984 LWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRL 1043 +D+ +P+ V++NA T+D +GP LR++WT+ P + L Sbjct: 6405 WMPVDEPGLREDP-----AVPVAAVVDVNAMTVDAGDGPELRSTWTYPPEVLTRAEVEEL 6459 Query: 1044 SRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRY-DVTDVLPLTPVQQGL 1102 ++LW +ALA + H GG G TPSD+ L Q I+ L +R D+TDV PL+P+Q G+ Sbjct: 6460 AQLWLQALAALGTHTESGGTGFTPSDLDLVALRQDAIEALERRCPDLTDVWPLSPLQSGM 6519 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFV-EQFGEPVQ 1161 LFH+ A D Y VQ+ + + G +D RLR A ++ARH NL A F+ + G VQ Sbjct: 6520 LFHAELADD-SLDAYLVQVSLELDGAVDPVRLRRAADALLARHDNLRAGFLRDTDGNAVQ 6578 Query: 1162 VLTADPMIAWRYLDLRG-DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHR 1220 V+ W +DL D+ EI +L A +R D+ P R LI T N++R Sbjct: 6579 VIRRRAEAPWLDVDLTALDEDAAASEIARLLADDRVRPFDMTRAPLIRFQLIATGPNRYR 6638 Query: 1221 FVLTFHHIVIDGWSLPILLQEIFAGYF----GHRLPAAAPYRNFVNWLXXXXXXXXXXXW 1276 V T HHI++DGWS+P+L++E+ Y LP YR+++ W W Sbjct: 6639 LVSTNHHILLDGWSMPLLIRELLTLYATGGDASPLPRIRGYRDYLAWAARRDQDASREVW 6698 Query: 1277 REVLDGFETPTLVAPPGVPGPRGIES----YRVSAETTRALGELARSQHTTINTVLQAAW 1332 L G E PTL+APP S + + ++T L ++ARS+ T+NT++Q +W Sbjct: 6699 ARALAGVEGPTLLAPPDRGHRLSTMSDEFVFDLDEQSTARLRDVARSRGLTVNTLVQVSW 6758 Query: 1333 TQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQ 1392 +L T + DV FG VSGRP +LAG E+MVG+ INT+P+R + TVG LL ++Q Sbjct: 6759 GIVLGASTARDDVLFGATVSGRPPELAGIETMVGMFINTLPVRIGLRPGETVGALLERVQ 6818 Query: 1393 SHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELA---VTEFNNR 1449 + L+H +L L++I +G E FDTL ++ESYP+D + ++A VT + R Sbjct: 6819 AEQAALLDHHYLGLSEIQGAAGPEAGFDTLTVFESYPVDRAGLTTDTDIAGMRVTGVDAR 6878 Query: 1450 EYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDV 1509 + HYPLS++A L L+ EY VFD + L R R+L+A P R L+++ + Sbjct: 6879 DAAHYPLSLVASVDARLHLKFEYLPDVFDADTVADLAGRVIRVLDA-CTRPDRPLAALSL 6937 Query: 1510 VDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEA 1569 + D ERT+L V +P S +++P++ DP A A+++ + YGELDE Sbjct: 6938 LTDRERTEL-----VPVRGRPGGSTRTLPQILEDGAALDPHAVALSYGDVDVTYGELDEH 6992 Query: 1570 ANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLG 1629 +N+LA L GA P VA+ +PRS D+++++ AV K+GAA++P+DP+ P R+ ML Sbjct: 6993 SNRLARALIARGAGPETFVAIGIPRSLDSVLSVWAVAKSGAAFVPVDPNYPDERITHMLV 7052 Query: 1630 DAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEI----YPSTTLLTP------SPDDIAY 1679 D+ +TT + R+R G D + +D+P I YP + + D AY Sbjct: 7053 DSGVTLGLTTTEHRNRLPG-DADWLLLDEPGFAIECAEYPGAAVTDADRSGPVTLDTAAY 7111 Query: 1680 MIYTSGTTGVPKGVAITHGNVTQ-VLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGAL 1738 +YTSG+TG+PKGV +TH + LD L A P + + + FD SV+E A Sbjct: 7112 AVYTSGSTGLPKGVVVTHRGLDNFALDQL-ERFGATPRSRTLHFSTPSFDGSVFEYLQAF 7170 Query: 1739 LHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG-TALVVAGEAC 1797 G +VI P ++ G D+L LL V + T +A+ + P GL T LV GEAC Sbjct: 7171 GAGATMVIAPPTVFGG-DELARLLADRNVTHAFITTAALASLDPAGLTHLTDLVFGGEAC 7229 Query: 1798 PTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRP 1857 P EVV RWA R + NAYGPTE+TI + ISAP+ PG + + IG P+ VLD L+P Sbjct: 7230 PPEVVARWAPGRRLYNAYGPTETTIMSNISAPMVPG-EPITIGGPIRGVTELVLDTRLQP 7288 Query: 1858 VPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQY 1917 VP GV GELYLA LT RFVA PF PG RMYRTGD+VRW D ++Y Sbjct: 7289 VPVGVAGELYLAGAGPARGYHRRPALTAERFVADPF-RPGERMYRTGDIVRWTPDHSIEY 7347 Query: 1918 LGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAA 1977 +GR D QVK+RG+RIELGE+ L V A +A GD LV Y+ ++ + Sbjct: 7348 VGRTDFQVKVRGFRIELGEVDGTLMSEPNVGFAATLAHRGPAGDTLLVSYVVPSSGSSLD 7407 Query: 1978 RSELT----NRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPE-YQSAQRYRAPETETE 2032 +ELT +RLP +MVP ++ LE +PLT GKLDR ALP P+ A YR P E Sbjct: 7408 TAELTRHLADRLPPHMVPTSITVLERIPLTAVGKLDRAALPEPDLLAGAGHYRVPAGPLE 7467 Query: 2033 KTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAK 2092 + +AG+FA VL + R A RVTA + +L D VR LFEAPTVA Sbjct: 7468 EAVAGVFADVLALGRVGADADFFDLGGNSLSATRVTARLRASLGVDCGVRDLFEAPTVAA 7527 Query: 2093 LS 2094 L+ Sbjct: 7528 LA 7529 Score = 1265 bits (3273), Expect = 0.0 Identities = 848/2188 (38%), Positives = 1142/2188 (52%), Gaps = 131/2188 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIE-VWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVA 59 +TA+P R + D+L E + V G AV P +P L AE V P+A A Sbjct: 2796 VTADPGAR-VGDIDILGSLERALLAPVPGGAAV------APRMLPDLMAEAVAHDPEATA 2848 Query: 60 LVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYL 119 LV + Y ELD SNRLA +L E GA P + V +PRS E++L++ ++ K+GAA+L Sbjct: 2849 LVFAGSAIRYGELDRRSNRLARMLIERGAGPESVVVLCVPRSVESVLAVWAIAKSGAAFL 2908 Query: 120 PVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADP----AIDRRPS--- 172 PVDP HP RI +M++D+ V LT + R L + + + DP A+ R PS Sbjct: 2909 PVDPNHPPKRIEYMLTDSGAVYGLTGSAHRGTLPGI-VPWLVLDDPGAGDALSRYPSSEI 2967 Query: 173 ---DALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWH 229 + LS R D+ AY+ YTSG+TG PK V TH + + + P + Sbjct: 2968 TDDERLSTIRADNPAYLIYTSGSTGTPKGVVTTHRGLAAFATQERETFGTTPESRTLHFA 3027 Query: 230 SLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPE 289 S FD SV E+ A+ +V+ P SV + L LL +E+V+ TP+A + P Sbjct: 3028 SPSFDASVLELLLAIGAAATMVIAPPSVYGGAE-LAQLLESERVTHCFVTPAALASIDPA 3086 Query: 290 GLESTTLIVAG-EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXX 348 GL +V G EACP ELV RWAPGR M NAYGPTEAT+ +++SE L Sbjct: 3087 GLPDLGCVVTGGEACPPELVARWAPGRHMFNAYGPTEATVVSSISEELVPGAPVTIGTPT 3146 Query: 349 XXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYR 408 VLD L P P GVVGELY+AG +A GY R LTA+ FVA PFG G RMYR Sbjct: 3147 LGFTET-VLDSRLHPVPAGVVGELYLAGPALARGYRRRHPLTAANFVADPFGPPGSRMYR 3205 Query: 409 TGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDK 468 TGD RW DGQLEYLGR D QVKIRG+RIELGE+++AL D V A D GD Sbjct: 3206 TGDRARWLPDGQLEYLGRTDSQVKIRGFRIELGEVESALLACDSVAHAAASVWNDGGGD- 3264 Query: 469 RLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEY 524 RL+GY+ + D + +A L +YMVP A+V+LD++PLTV+GKLDR ALPAP++ Sbjct: 3265 RLIGYVVPESGASIDSRAVLDFVACRLASYMVPAALVILDSLPLTVHGKLDRTALPAPDF 3324 Query: 525 RSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQ 584 A + R P T E +LA ++ VLGV+ VG DDSFF LGGDSI S+Q+VA ARAAG+ Sbjct: 3325 --AGSGSRPPQTETEALLAGLFEDVLGVDSVGADDSFFSLGGDSIQSIQLVAHARAAGVI 3382 Query: 585 CRPRDIFVEQTXXXXXXXXXXXXESHV-VDE----GVGPVVATPIMRWLRE-VDGPTGQF 638 PRD+F +T + V +DE GVG + TP+ RW+ E G +F Sbjct: 3383 LSPRDVFDHRTVSGLAAAARFDHDGTVALDELPGGGVGSLPLTPVARWMFERSGGRLDRF 3442 Query: 639 NQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGAREC 698 +Q ++ APA +T + +V ++A+LDRH LR V + + T+ V G+V A Sbjct: 3443 SQALLLTAPADLTHEVLVGAVEAVLDRHDMLRALV--SADGTN-----VLPTGSVPAEVH 3495 Query: 699 LRTVDALTDD--------VLVEARNRLDPAAGAMVSAVWV---RETSQLVLMIHHLAVDG 747 VDA+ + L A + LDPAA + VW + +L++++HHL VDG Sbjct: 3496 RVPVDAVRGEEFTALAAAELEAAADHLDPAAARTLRVVWFDVPDDAGRLLVVVHHLVVDG 3555 Query: 748 VSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTS 807 VSWRIL+ DL A + G + LPA GTS RWS L E +T T +LA +W + Sbjct: 3556 VSWRILVADLASAAERLGAGLTPALPAVGTSMRRWSHGLTEAVRTRT-GELA-SWEKILD 3613 Query: 808 VPQAL---PPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGL-- 862 P L P+ P D T G ++ + E T LL +P A V D LL A L Sbjct: 3614 GPDPLIGSRPLDPAIDVAATVGTVTVDVPPEVTDALLTALPDAVHGSVGDGLLTAIALAL 3673 Query: 863 -AWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVA 921 AW + + +EGHGR +++ DLSRTVGWFTT YP L + + + +A Sbjct: 3674 IAWRRERGGAVPDTLLTLEGHGREEQVVPGADLSRTVGWFTTVYPARLDLTGIEVDDALA 3733 Query: 922 GDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEVDLGGSD-------PTIGFNYLGRL 973 G AA G VKAVKEQL ++P+ G+ +GLLRYL+ E GS+ P +GFNYLGR+ Sbjct: 3734 GGAAAGQAVKAVKEQLLAIPDHGIGFGLLRYLDDE----GSEALHRFRTPQVGFNYLGRV 3789 Query: 974 ---GAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTW 1030 G G L E MP+ +++NA DT G LRAS+ + Sbjct: 3790 VVTGGGENWLPVE---------STLGGTTNPDMPVASVIDINAVVSDTPEGARLRASFAF 3840 Query: 1031 APSAFDEEQATRLSRLWFEALAGICAH-VRGGGGGLTPSDVAPARLTQRQIDELSQRYD- 1088 EE+ + LW AL G+ H R GG TPSD+ QRQI+ +R+ Sbjct: 3841 PTGVLSEEEVAAFADLWRRALGGLAVHTARPDAGGRTPSDLPLVSANQRQIERWEERFPA 3900 Query: 1089 VTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNL 1148 + DV PL+P+Q GLLFH++ A DVY QL I G +D RLR A ++ARH NL Sbjct: 3901 LQDVWPLSPLQSGLLFHASLA-AESMDVYTAQLRIDFEGEVDAQRLRAAAAGLLARHANL 3959 Query: 1149 AARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHE--IEQLCAAERSAVCDLLERPT 1206 FV G P Q++ + WR +DL D D + + +L +RSA DL P Sbjct: 3960 RTAFVYDDGVPAQIVLDAVEVPWREVDLTDTDTDTDTDTALVRLLDEDRSARFDLARPPL 4019 Query: 1207 FRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP----YRNFVN 1262 R L T+ +T HHIV+DGWS+P+L++E+ Y PA P YR ++ Sbjct: 4020 LRLTLFHTAPKCFVLSITNHHIVLDGWSIPLLVRELLVRYASGGDPAGLPEPPSYRTYLE 4079 Query: 1263 WLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIE---SYRVSAETTRALGELARS 1319 W+ W LDG E PTL+AP G+ + A L A Sbjct: 4080 WVASRDTELSARAWERALDGVEEPTLLAPHASAALHGVPHELDVDLPAGILDGLAATANR 4139 Query: 1320 QHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVS 1379 T+NTV QAAW LL R + DV FG VSGRP L G E+M+GL INTVP+R +V Sbjct: 4140 AGVTMNTVTQAAWGILLSRSVSREDVIFGATVSGRPPQLPGVETMLGLFINTVPVRVRVD 4199 Query: 1380 ADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAF---M 1436 D TV LL +LQ L+H HL L +I G LFDTL ++ESYPIDTS Sbjct: 4200 PDETVAGLLTRLQDEQTSLLDHHHLGLGEIQSRIGLGNLFDTLSVFESYPIDTSGLDENT 4259 Query: 1437 GVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAM 1496 V + VT + R+ HYP++++ + L L + Y + D + + L DR R+L + Sbjct: 4260 DVGGVRVTGLDARDATHYPVTLLTIVEPRLRLSLRYQPGILDRATVAALADRLVRILGTI 4319 Query: 1497 IDDPARRLSSMDVVDDDER-TQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVT 1555 DP + ++V+ ER + W T V S+ ++F QV R P APAV Sbjct: 4320 AGDPDTVVGDVEVLGPGERGLVVGSWN----ATSHVVPGVSVADLFVAQVGRSPGAPAVV 4375 Query: 1556 FEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPI 1615 L+YGE +LA L G P SV + V RS D +V + AV+ G A++PI Sbjct: 4376 CGEVVLSYGEFAARVYRLARWLIGEGVGPESSVGVAVRRSVDMVVGVYAVVVAGGAFVPI 4435 Query: 1616 DPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVE------IYPSTTL 1669 DP P R+ +++G A PV +TT F G ++VV VD+ V + L Sbjct: 4436 DPDQPVERVGYVVGTAAPVLVLTTSADVGVFAG-SVRVVAVDELDVSGLGAGPVGDGERL 4494 Query: 1670 LTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDV 1729 P Y+++TSG+TG PKGV++ H + L + G V Q + FDV Sbjct: 4495 ARLRPGCPGYVMFTSGSTGRPKGVSVPHAGIVNRLLWMQDRYRLGSDDVVLQKTPVTFDV 4554 Query: 1730 SVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRM-MSPEGLEGT 1788 SVWE++ L+ G RLVI P L ++ E V ++ PS + + ++ +EG Sbjct: 4555 SVWELFWPLVVGARLVIAEPGGHRDPAYLERVIREESVTTVHFVPSMLEVFLAGANVEGC 4614 Query: 1789 A----LVVAGEACPTEVVDRWAVDRV----MINAYGPTESTIYAAISAPLSPGSDVVPIG 1840 + +GEA P+ R + RV + N YGPTE+++ VVPIG Sbjct: 4615 GALRRVFTSGEALPSASAAR--LRRVSGTELHNLYGPTEASVDVTFHEVTDADRVVVPIG 4672 Query: 1841 SPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGE---PG 1897 +PV T VLD LRPVP GV GELYL LT RFVA PFG G Sbjct: 4673 APVWNTQTVVLDGRLRPVPVGVAGELYLGGVQLARGYVGRAELTAERFVANPFGAGDGRG 4732 Query: 1898 ARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARED 1957 +R+YRTGD VRW G+L+YLGR D QVK+RG R+ELGE++A L V QAVV+ R D Sbjct: 4733 SRLYRTGDRVRWLRSGELEYLGRTDFQVKLRGQRVELGEVEAVLLRRVEVAQAVVVLRGD 4792 Query: 1958 RPGDKRLVGYITGTA----DPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRAL 2013 + L GY+ A D A R + +P +MVP+ VV L LP+TVNGKLDR+AL Sbjct: 4793 GAAGEYLAGYVVPVAGAVVDERAVRESVAAVVPGFMVPSVVVVLAELPVTVNGKLDRKAL 4852 Query: 2014 PAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVN 2072 P P++ + R YR P T E+ +A FA VLG++R A R +N Sbjct: 4853 PTPDFGTTTRGYRVPTTPAEEAVASAFAAVLGIDRVGADDSFLDLGGDSLSATRAVGRIN 4912 Query: 2073 TALDADLSVRTLFEAPTVAKLSLHVEHD 2100 +ALD DL V LF+AP VA L+ ++ D Sbjct: 4913 SALDTDLGVAALFDAPVVADLAARIDSD 4940 Score = 501 bits (1289), Expect = e-139 Identities = 377/1076 (35%), Positives = 526/1076 (48%), Gaps = 104/1076 (9%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ QQ + F + F Y + + + + G LD LR A+ V+ RH +L F Sbjct: 4959 IPLSLAQQRMWFVNQF--DTASPAYNIPVALQLDGALDLDALRAALGDVLERHESLRTVF 5016 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHE--IEQLCAAERSAVCDLLERPTFRAA 1210 P Q MIA L G + P E + + A A D+ E R Sbjct: 5017 PGSADGPRQ------MIADSALVTPGLEPVPVAEGALRESLTAFFGAGFDVTEDVPIRVR 5070 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXXXX 1270 L+R + +H L HHI DG+S+ L +++ Y R AP W Sbjct: 5071 LVRLAPERHVLALVVHHIAADGFSMAPLARDVMLAYTA-RAQGHAP-----GWAPLPVQY 5124 Query: 1271 XXXXXW-REVLD-------------GFETPTLVAPPGV---------PGPRG----IESY 1303 W RE L G+ T TL P V P R + + Sbjct: 5125 ADYGLWQREALGTDEQPDSMISGLLGYWTRTLSGIPDVLPLPLDRPRPAQRSHLGAVVPF 5184 Query: 1304 RVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAES 1363 + + +L ++AR ++T+ V+ AA LL R+TG DV GT ++GR A + Sbjct: 5185 DIPPDVHESLTDIARQSNSTLFMVVHAALAVLLARVTGSEDVVLGTPIAGRGH--AALDD 5242 Query: 1364 MVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQ 1417 +VG+ +NT+ +R V A ++ +LL ++S EH L + + H Sbjct: 5243 VVGMFVNTLVLRTPVPAGSSFTELLTGVRSVDLGAFEHADLPFERLVDELAPERSTAHSP 5302 Query: 1418 LFDTLFLYESYPIDTSAFMGVQ------ELAVTEFNNREYNHYPLSVMALP-GHELGLRV 1470 LF L +++ G+ +L V +F+ + + +P G G+R Sbjct: 5303 LFQVLLEFQNATRTHLELPGLTARSVDVDLDVAKFDLQLSLVERVDEQGVPAGVSAGVR- 5361 Query: 1471 EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQP 1530 Y T V D + +E +RF R+LEA+ DPA + +D++D ER + A+R Sbjct: 5362 -YATDVLDRASVEGFAERFVRVLEAVTTDPAAPVGDIDILDAPERGLVLTSAHRPGTDV- 5419 Query: 1531 VDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVAL 1590 +P S+ ++F R + EA AV EG S+ Y ELDE AN+LA LL GA VA+ Sbjct: 5420 --APLSLVDLFDRAAAAEAEAVAVRCEGSSVTYRELDERANRLARLLVARGAGAETLVAV 5477 Query: 1591 MVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFD 1650 + RS D +VA++AV+K+GA YLP+D PA RL F+LGDA+P +TT F G Sbjct: 5478 GMTRSVDLVVALVAVVKSGAGYLPVDVDSPADRLAFLLGDARPGCVLTTTADAETFRGAG 5537 Query: 1651 LQVVEVDDPAVEIYPSTTLLTPSP------------DDIAYMIYTSGTTGVPKGVAITHG 1698 + VV VDDPA + L+P P D +AY+IYTSG+TG PKGV ++H Sbjct: 5538 VPVVVVDDPAT--VTALQPLSPLPVTDDDRRTPLHLDSVAYVIYTSGSTGQPKGVQVSHR 5595 Query: 1699 NVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDL 1758 NV ++ GP VW+ +HS FD SVWE+WGAL HGGRLV V A SP+ Sbjct: 5596 NVVTLVANTQTLFGFGPADVWTMFHSAAFDFSVWEMWGALAHGGRLVPVDYFTARSPEKF 5655 Query: 1759 HALLVSEGVNVLYQTPSAV-------RMMSPEGLEGTALVVAGEACPTEVVDRWAVDR-- 1809 LL +E V V+ QTP+A R+ L ++ GEA + RW R Sbjct: 5656 LELLRAEHVTVVNQTPTAFYQLAEADRLAGGPALSLRYVIFGGEALDFGQLRRWYARRGD 5715 Query: 1810 ---VMINAYGPTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVV 1863 V+ N YG TE+T++ + L+ + IG +P +VLD L PVPPGVV Sbjct: 5716 TAPVLANMYGITETTVHVTHLPVDRDLAREASGSLIGRGLPGLRVYVLDGRLHPVPPGVV 5775 Query: 1864 GELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADE 1923 GE+Y+ LT RFVA PF PGARMYR+GDL RW GQL+YLGR D Sbjct: 5776 GEMYVCGAQVSRGYLGRPALTSGRFVADPF-VPGARMYRSGDLGRWNAHGQLEYLGRNDL 5834 Query: 1924 QVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAAARS 1979 QV+++GYRIELGE+++AL +GV QA V AR D RLVGY+ A DPA Sbjct: 5835 QVQVKGYRIELGEVESALLASEGVAQAAVTARGD-----RLVGYVVPEAGAAIDPAVVLD 5889 Query: 1980 ELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGI 2038 RL ++MVPAAVV L +PLTVNGKLDR+ALP P++ Q R P TETE+ LA + Sbjct: 5890 AAAERLASHMVPAAVVVLGGMPLTVNGKLDRKALPEPDFGQRVTAGRGPVTETERILADL 5949 Query: 2039 FAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 FA VLG+ ++++ A +S R +FE TVA L+ Sbjct: 5950 FAEVLGLGSVGVDDSFFALGGDSIMSIQLVTRAKAA-GVLISPRDVFERKTVAALA 6004 Score = 499 bits (1285), Expect = e-138 Identities = 372/1093 (34%), Positives = 520/1093 (47%), Gaps = 91/1093 (8%) Query: 1090 TDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLA 1149 T +P++P QQ + F + F Y V + + G LD H L+ AV VV RH + Sbjct: 2365 TAEVPVSPAQQRMWFINQF--DTSSSAYNVAFALRLEGRLDVHALQAAVADVVERHEAVR 2422 Query: 1150 ARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA 1209 F P QV+ A DL + + E+ + SA D+ + RA Sbjct: 2423 TLFPLADDGPRQVVLP---AANAVPDLAPVVVPGEAELREHSLILLSAGFDVTTQVPLRA 2479 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHR-------LPAAAPYRNFVN 1262 L R N H + HHI DG+S+ L +++ A Y LP Y ++ Sbjct: 2480 KLFRLDENLHVLAVVVHHIAADGFSMAPLARDVMAAYVSRSNGSAPDWLPLDVQYADYAL 2539 Query: 1263 WL---------XXXXXXXXXXXWREVLDG----FETPTLVAPPGVPGPRGIE-SYRVSAE 1308 W W L E PT P V RG + + + Sbjct: 2540 WQREWLGSESDDRSPVSRQLAYWTATLSDLPELLELPTDRPRPSVRSLRGGRVEFVIDPD 2599 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLL 1368 + LAR TT+ L AA +L R++G D+A GT +GR + +VG+ Sbjct: 2600 IHAGVVRLAREHATTVFMTLHAALAVVLARVSGANDIAVGTPTAGRGE--RELDDVVGMF 2657 Query: 1369 INTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHV------SGHEQLFDTL 1422 +NT+ +R V T + L +++ H + + V + + LF + Sbjct: 2658 VNTLVLRTHVDGAATFAEFLDRVRETDLGAFTHAEVPFERVVEVLSPSRATAYAPLFQVM 2717 Query: 1423 FLYE-----------------SYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHE 1465 ++ + IDT+ F +L T + N YP + A G Sbjct: 2718 LEFQDIERPTLELPDLQIRNLDFEIDTANF----DLQWTLTETFDENGYPAGITAGLG-- 2771 Query: 1466 LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRA 1525 Y T +FD +RF R+LEA+ DP R+ +D++ ER L A Sbjct: 2772 ------YATDLFDEETAIGFAERFVRILEAVTADPGARVGDIDILGSLERALLAPVPGGA 2825 Query: 1526 VLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPG 1585 + +P+ +P++ A V DPEA A+ F G ++ YGELD +N+LA +L GA P Sbjct: 2826 AV-----APRMLPDLMAEAVAHDPEATALVFAGSAIRYGELDRRSNRLARMLIERGAGPE 2880 Query: 1586 KSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSR 1645 V L VPRS ++++A+ A+ K+GAA+LP+DP+ P R+E+ML D+ V +T R Sbjct: 2881 SVVVLCVPRSVESVLAVWAIAKSGAAFLPVDPNHPPKRIEYMLTDSGAVYGLTGSAHRGT 2940 Query: 1646 FDGFDLQVVEVDDP----AVEIYPST------TLLTPSPDDIAYMIYTSGTTGVPKGVAI 1695 G +V +DDP A+ YPS+ L T D+ AY+IYTSG+TG PKGV Sbjct: 2941 LPGIVPWLV-LDDPGAGDALSRYPSSEITDDERLSTIRADNPAYLIYTSGSTGTPKGVVT 2999 Query: 1696 THGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSP 1755 TH + P + + S FD SV E+ A+ +VI P S+ G Sbjct: 3000 THRGLAAFATQERETFGTTPESRTLHFASPSFDASVLELLLAIGAAATMVIAPPSVYGGA 3059 Query: 1756 DDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVV-AGEACPTEVVDRWAVDRVMINA 1814 +L LL SE V + TP+A+ + P GL VV GEACP E+V RWA R M NA Sbjct: 3060 -ELAQLLESERVTHCFVTPAALASIDPAGLPDLGCVVTGGEACPPELVARWAPGRHMFNA 3118 Query: 1815 YGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXX 1874 YGPTE+T+ ++IS L PG+ V IG+P VLD L PVP GVVGELYLA Sbjct: 3119 YGPTEATVVSSISEELVPGAPVT-IGTPTLGFTETVLDSRLHPVPAGVVGELYLAGPALA 3177 Query: 1875 XXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIEL 1934 LT FVA PFG PG+RMYRTGD RW DGQL+YLGR D QVKIRG+RIEL Sbjct: 3178 RGYRRRHPLTAANFVADPFGPPGSRMYRTGDRARWLPDGQLEYLGRTDSQVKIRGFRIEL 3237 Query: 1935 GEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTNRLPAYMV 1990 GE+++AL D V A D GD RL+GY+ + D A + RL +YMV Sbjct: 3238 GEVESALLACDSVAHAAASVWNDGGGD-RLIGYVVPESGASIDSRAVLDFVACRLASYMV 3296 Query: 1991 PAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXX 2050 PAA+V L++LPLTV+GKLDR ALPAP++ + R P+TETE LAG+F VLGV+ Sbjct: 3297 PAALVILDSLPLTVHGKLDRTALPAPDF-AGSGSRPPQTETEALLAGLFEDVLGVDSVGA 3355 Query: 2051 XXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKL--SLHVEHDAGERTDRV 2108 ++++ A A LS R +F+ TV+ L + +HD D + Sbjct: 3356 DDSFFSLGGDSIQSIQLVAHARAA-GVILSPRDVFDHRTVSGLAAAARFDHDGTVALDEL 3414 Query: 2109 SFAAVHGSDVTEV 2121 V +T V Sbjct: 3415 PGGGVGSLPLTPV 3427 Score = 457 bits (1177), Expect = e-126 Identities = 342/1069 (31%), Positives = 504/1069 (47%), Gaps = 98/1069 (9%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D +PL+ QQ + F + Y + + +T++G LD L A+ V+ARH +L Sbjct: 7553 DDIPLSFAQQRMWFVNQL--DTTSAAYNIPIVVTLSGDLDVGALNSALTDVLARHESLRT 7610 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 F + PVQ + + + + E+ +L +A +L RA Sbjct: 7611 MFPVRGDWPVQQILPAAGAVPALIPVTVTEEHVRDEVSRLVSAGFDVTVEL----PLRAG 7666 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP--------YRNFVN 1262 L S ++ + HHI DG+S+ L++++ A Y G R AAP Y ++ Sbjct: 7667 LYSLSATEYVLAVVVHHISADGFSMGPLVRDVMAAY-GARASGAAPDWAPLPVQYADYAL 7725 Query: 1263 WLXXXXXXXXXXX---------WREVLDG----FETPTLVAPPGVPGPRGIE-SYRVSAE 1308 W W L G E PT P RG + V + Sbjct: 7726 WQRELLGSDDDPESLLSRQLDYWTTALAGTPDLLELPTDRDRPSQQSFRGARVHFSVDGD 7785 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGR--PADLAGAESMVG 1366 R + EL+R +T + AA LL R+ G DVA GT V+GR PA + +VG Sbjct: 7786 LHRRIRELSRRLGSTEFMTVHAALAVLLSRLGGTPDVAVGTPVAGRGDPA----LDGLVG 7841 Query: 1367 LLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYE 1426 + + T+ +R +V + L + H + + G Sbjct: 7842 MFVGTLALRTRVDPAASFTALAGHCRDVDLAAFAHADVPFERVVDAVG------------ 7889 Query: 1427 SYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGL------------------ 1468 P ++AF + ++++ EF N E L + + G + GL Sbjct: 7890 --PTRSTAFAPLAQVSL-EFQNTERPVLTLPGLDVRGIDSGLAVVKVDLEFLLAEEFGAD 7946 Query: 1469 --------RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDE 1520 V++ T +FD + DRF R+L+A+ +P R + + ++D+ E Sbjct: 7947 GAPAGMSGAVDFATDLFDAGTVRGFADRFVRILDAVTANPDRPVGDLPLLDETELR---- 8002 Query: 1521 WANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVY 1580 A P PQ P++ DP++ A+++E ++Y ELDE +N+ A +L Sbjct: 8003 -AMAPARGGPDVRPQLWPDLLTAAAAFDPDSVALSYEDRRVSYRELDEWSNRWARILRGR 8061 Query: 1581 GAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTT- 1639 G P VA+ +PRS +++VAI ++ K GAA++P+DP+ P R+++ML D + +T Sbjct: 8062 GVGPETFVAVGMPRSIESVVAIWSITKAGAAFVPVDPTYPRERIDYMLTDCRAALGLTVR 8121 Query: 1640 ---GDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDI-----AYMIYTSGTTGVPK 1691 GDL L EV + P+ + AY+IYTSG+TG PK Sbjct: 8122 SRRGDLPDTVPWLMLDDEEVTAQVAAVSPAPVTDADRTGPLHLAHPAYLIYTSGSTGRPK 8181 Query: 1692 GVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESI 1751 GV +TH + + SQ S FD SV+E+ A ++VIVP ++ Sbjct: 8182 GVTVTHRGMADFTAETHERFQVSHESRVSQLASPSFDASVFELMMAFSASAQVVIVPPAV 8241 Query: 1752 AGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG-TALVVAGEACPTEVVDRWAVDRV 1810 G +L L E V TP+A+ + +GL+ L + GEACP EVV RWA R Sbjct: 8242 LGG-SELADLFRREQVTHATITPTALAALDNDGLDALRVLDLVGEACPPEVVARWAPGRS 8300 Query: 1811 MINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAX 1870 + + YGPTE+TI A++SAP+ PG + V IGSP A VLDE L+PVP GV GELY+A Sbjct: 8301 LHSGYGPTETTIQASVSAPMRPG-ESVNIGSPALGFAFLVLDERLQPVPAGVPGELYIAG 8359 Query: 1871 XXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGY 1930 LT RFVAC FGEPG RMYRTGD+VRW D L+YLGR+D QVK+RG+ Sbjct: 8360 PGTARGYHNRPDLTSERFVACNFGEPGCRMYRTGDVVRWRRDHTLEYLGRSDFQVKVRGF 8419 Query: 1931 RIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITG----TADPAAARSELTNRLP 1986 RIELGEI A L V A + GD L Y+ G PA R+ RLP Sbjct: 8420 RIELGEIDAVLGRHPAVAFAATVGHTGPSGDTVLASYVRGHDGQEVQPAGLRTYAAERLP 8479 Query: 1987 AYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFAHVLGV 2045 A+MVP+AVV L+ +P+T GKLDR+ALPAPE+ S +RAP TETE+ + +FA VLG+ Sbjct: 8480 AHMVPSAVVVLDRIPMTPVGKLDRKALPAPEFGSTGAAFRAPATETERIVVDVFASVLGL 8539 Query: 2046 ERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +R A R+ +A+ LD + ++ +F PT A ++ Sbjct: 8540 DRVGTADSFFDLGGNSLLATRIVSALQAELDRRVPLQWMFLDPTPAGIA 8588 Score = 452 bits (1163), Expect = e-124 Identities = 318/839 (37%), Positives = 429/839 (51%), Gaps = 61/839 (7%) Query: 1305 VSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESM 1364 + A T R + LA TT+ VL AA LL R++G DVA GT V P D Sbjct: 496 IGAGTHRGVRALAEDHDTTLFGVLHAAAAVLLSRLSGAADVAVGTMV---PVDRGQ---- 548 Query: 1365 VGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFL 1424 N V +R + D T + LR + + + EH + HV L D+ Sbjct: 549 -----NLVVLRTRAPLDATFTEHLRYVDAVDREAFEHRDVPFE---HVVRAVALRDSPAF 600 Query: 1425 YESYPI----DTSAFMGVQ--ELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFD 1478 + D + G+ +L VT + + P + G + L FD Sbjct: 601 SPIVQVLVDGDAAGPPGIGRFDLRVTAAETFDADGLPAGITVTLGFAVDL--------FD 652 Query: 1479 VSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSP-QSI 1537 + L +RF+R+LEA DP + +D++ D ER L + P P +++ Sbjct: 653 PGTVRRLGERFRRILEAATGDPGVVVGDIDILSDAERATL------VPVPGPAGRPGRAL 706 Query: 1538 PEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSAD 1597 PE+F+ +P A+++ G + Y ELDE ++QLA +LA +G P VAL + RS + Sbjct: 707 PELFSAATRANPTGTALSYLGHDVTYRELDERSSQLARVLAEHGIGPENVVALGMTRSIE 766 Query: 1598 AIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVD 1657 +++++LAV K GAA+LP DP+ PA R+E ML D+ VT +RSR G +V + Sbjct: 767 SVLSMLAVGKAGAAFLPADPNYPAERIEHMLDDSGAALGVTVSTVRSRLPGSVPWLVLDE 826 Query: 1658 D---------PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLP 1708 D P + S + P++ AY+IYTSG+TG PKGV +TH LD Sbjct: 827 DEFRLHCASRPNSAVTDSDRVRPLRPENPAYVIYTSGSTGRPKGVVVTHRG----LDNFA 882 Query: 1709 AELPAGPGAVWSQ----WHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVS 1764 AE A GA + + + FD SV E +VIVP +I G ++L L S Sbjct: 883 AEQLARSGASRTSRVLHFSTPSFDASVSEYLHVFAAAATMVIVPPTIYGG-EELSRFLRS 941 Query: 1765 EGVNVLYQTPSAVRMMSPEGLEGTA-LVVAGEACPTEVVDRWAVDRVMINAYGPTESTIY 1823 E V + T +A+ + P+GL G +V+ GEACP E+V RWA R + NAYGPTE+T+ Sbjct: 942 ERVTHGFVTTAALGTIDPDGLSGFGDVVLGGEACPPELVQRWAPGRRLSNAYGPTEATVM 1001 Query: 1824 AAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXL 1883 + ISAP+ P V +G P+ VLDE L PVP GV GELY++ L Sbjct: 1002 SNISAPMQPDG-AVTLGGPLRGFREVVLDERLSPVPAGVAGELYISGDGLARGYRGRSAL 1060 Query: 1884 TGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSD 1943 T RFVA PFG PG RMYRTGD+VRW D L+Y+GR+D QVK+RG+RIELGEI L Sbjct: 1061 TAERFVADPFGGPGDRMYRTGDVVRWRTDRTLEYVGRSDFQVKMRGFRIELGEIDTVLHA 1120 Query: 1944 VDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTN----RLPAYMVPAAVVTLET 1999 V AV +R GD LV Y+ A +ELT+ +LP YMVPAA+V L+ Sbjct: 1121 HPHVRTAVTTSRTAPSGDTVLVSYVLPAAGQRLTATELTDLAAKQLPTYMVPAAIVVLDE 1180 Query: 2000 LPLTVNGKLDRRALPAPEYQSAQ-RYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXX 2058 LPLT GKLDR ALPAPE+ SA+ +R P T E+T+A +FA VLGVER Sbjct: 1181 LPLTPAGKLDRAALPAPEFLSAKTEFRVPVTAEEQTVARVFADVLGVERIGLDDSFFDLG 1240 Query: 2059 XXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAAVHGSD 2117 A RV A +N AL DL VRTLFEAPTV L+ + DR A D Sbjct: 1241 GNSLAATRVVARLNAALGVDLVVRTLFEAPTVEALAERIGSAHTRPADRPDLVAQRRPD 1299 Score = 426 bits (1094), Expect = e-116 Identities = 305/849 (35%), Positives = 434/849 (51%), Gaps = 50/849 (5%) Query: 36 PGPTPV---TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGA 92 PGP +P LF+ P AL TYRELDE S++LA VLAEHG P Sbjct: 696 PGPAGRPGRALPELFSAATRANPTGTALSYLGHDVTYRELDERSSQLARVLAEHGIGPEN 755 Query: 93 TVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRL 152 VA + RS E++LS+L+V K GAA+LP DP +P RI M+ D+ +T + +RSRL Sbjct: 756 VVALGMTRSIESVLSMLAVGKAGAAFLPADPNYPAERIEHMLDDSGAALGVTVSTVRSRL 815 Query: 153 -----------DQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAV 201 D++ L + A+ SD + RP++ AY+ YTSG+TG PK V V Sbjct: 816 PGSVPWLVLDEDEFRLHCASRPNSAVT--DSDRVRPLRPENPAYVIYTSGSTGRPKGVVV 873 Query: 202 THHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSP 261 TH + + A + + + FD SV E +V+VP ++ Sbjct: 874 THRGLDNFAAEQLARSGASRTSRVLHFSTPSFDASVSEYLHVFAAAATMVIVPPTIYGG- 932 Query: 262 DDLHNLLITEKVSVLCQTPSAAGMLSPEGLEST-TLIVAGEACPTELVDRWAPGRVMINA 320 ++L L +E+V+ T +A G + P+GL +++ GEACP ELV RWAPGR + NA Sbjct: 933 EELSRFLRSERVTHGFVTTAALGTIDPDGLSGFGDVVLGGEACPPELVQRWAPGRRLSNA 992 Query: 321 YGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVA 380 YGPTEAT+ + +S P+ + VLD+ L P P GV GELY++G G+A Sbjct: 993 YGPTEATVMSNISAPMQPDGAVTLGGPLRGFREV-VLDERLSPVPAGVAGELYISGDGLA 1051 Query: 381 TGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIEL 440 GY GR LTA RFVA PFG G+RMYRTGD+VRW +D LEY+GR+D QVK+RG+RIEL Sbjct: 1052 RGYRGRSALTAERFVADPFGGPGDRMYRTGDVVRWRTDRTLEYVGRSDFQVKMRGFRIEL 1111 Query: 441 GEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPAQLRTAL----AESLPAYMV 496 GEI L V AV +R GD LV Y+ A T L A+ LP YMV Sbjct: 1112 GEIDTVLHAHPHVRTAVTTSRTAPSGDTVLVSYVLPAAGQRLTATELTDLAAKQLPTYMV 1171 Query: 497 PTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVG 556 P A+VVLD +PLT GKLDR ALPAPE+ SA ++R P T EQ +A V+A VLGVER+G Sbjct: 1172 PAAIVVLDELPLTPAGKLDRAALPAPEFLSAKTEFRVPVTAEEQTVARVFADVLGVERIG 1231 Query: 557 VDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXXXXXXXXXXESHVVD-- 613 +DDSFFDLGG+S+ + +VVAR AA G+ R +F E + D Sbjct: 1232 LDDSFFDLGGNSLAATRVVARLNAALGVDLVVRTLF-EAPTVEALAERIGSAHTRPADRP 1290 Query: 614 --------EGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDR 665 + + +A + ++ + D + +N + + + E + + +L R Sbjct: 1291 DLVAQRRPDRIPLSLAQQRLWFVNQYDTSSPAYNIPMALRLTGTLDEAALRTAVGDILGR 1350 Query: 666 HATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVD--ALTDDVLVEARNRLDPAAGA 723 H +LR + + + +++P + A E D AL + A D + A Sbjct: 1351 HESLRTVYPASVDGPHQ--VILPLGDVMPALEPTIVDDEAALRAQTVELAARGFDVSTEA 1408 Query: 724 MVSAVWVR--ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTS 778 V R + LVL++HH++ DG S L DL +A++ Q + LP Sbjct: 1409 PVRGALFRTGQAHVLVLVVHHISADGASLAPLARDLMVAYSARVRQQPPDWRPLPVQYAD 1468 Query: 779 FARW--SALLAEHAKTDTVRDLADAW-RAVTSVPQA--LPPVQP-DTDTYVTAGQLSASL 832 ++ W +AL +E + + W R ++ +P LP +P TD + + ++ Sbjct: 1469 YSLWQRAALGSEDHPGSVMSAQVEYWKRTLSGLPDVIDLPLDRPRPTDRTLRGETVRFTV 1528 Query: 833 DVETTRQLL 841 E R LL Sbjct: 1529 SAEDHRSLL 1537 Score = 421 bits (1083), Expect = e-115 Identities = 301/817 (36%), Positives = 412/817 (50%), Gaps = 62/817 (7%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R L + LL + E ++ R PG + T+P + + P AVAL GD Sbjct: 6930 RPLAALSLLTDRERTELVPVRGR-----PGGSTRTLPQILEDGAALDPHAVALSYGDVDV 6984 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 TY ELDE SNRLA L GA P VA IPRS +++LS+ +V K+GAA++PVDP +PD Sbjct: 6985 TYGELDEHSNRLARALIARGAGPETFVAIGIPRSLDSVLSVWAVAKSGAAFVPVDPNYPD 7044 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLD-QYDLAVIDMADPAID--RRPSDAL-----SGPR 179 RI M+ D+ LTT + R+RL D ++D AI+ P A+ SGP Sbjct: 7045 ERITHMLVDSGVTLGLTTTEHRNRLPGDADWLLLDEPGFAIECAEYPGAAVTDADRSGPV 7104 Query: 180 P-DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVW 238 D AY YTSG+TG+PK V VTH + + P + + FD SV+ Sbjct: 7105 TLDTAAYAVYTSGSTGLPKGVVVTHRGLDNFALDQLERFGATPRSRTLHFSTPSFDGSVF 7164 Query: 239 EIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTT-LI 297 E A G +V+ P +V D+L LL V+ T +A L P GL T L+ Sbjct: 7165 EYLQAFGAGATMVIAPPTVFGG-DELARLLADRNVTHAFITTAALASLDPAGLTHLTDLV 7223 Query: 298 VAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVL 357 GEACP E+V RWAPGR + NAYGPTE TI + +S P+ L VL Sbjct: 7224 FGGEACPPEVVARWAPGRRLYNAYGPTETTIMSNISAPMVPGEPITIGGPIRGVTEL-VL 7282 Query: 358 DKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGS 417 D L+P P GV GELY+AG G A GY RP LTA RFVA PF GERMYRTGD+VRW Sbjct: 7283 DTRLQPVPVGVAGELYLAGAGPARGYHRRPALTAERFVADPF-RPGERMYRTGDIVRWTP 7341 Query: 418 DGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGT 477 D +EY+GR D QVK+RG+RIELGE+ L V A +A GD LV Y+ + Sbjct: 7342 DHSIEYVGRTDFQVKVRGFRIELGEVDGTLMSEPNVGFAATLAHRGPAGDTLLVSYVVPS 7401 Query: 478 A----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRA 533 + D A+L LA+ LP +MVPT++ VL+ IPLT GKLDR ALP P+ + A YR Sbjct: 7402 SGSSLDTAELTRHLADRLPPHMVPTSITVLERIPLTAVGKLDRAALPEPDLLAGAGHYRV 7461 Query: 534 PSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFV 592 P+ P E+ +A V+A VL + RVG D FFDLGG+S+ + +V AR RA+ G+ C RD+F Sbjct: 7462 PAGPLEEAVAGVFADVLALGRVGADADFFDLGGNSLSATRVTARLRASLGVDCGVRDLFE 7521 Query: 593 EQTXXXXXXXXXXXXESHVVDEGVGPV------------------VATPIMRWLREVDGP 634 T + G GP A M ++ ++D Sbjct: 7522 APTVAALA--------ERIAQSGAGPSGRPVLTAARIRPDDIPLSFAQQRMWFVNQLDTT 7573 Query: 635 TGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSL--LVPEAGA 692 + +N ++ + + L +L RH +LR +W + ++P AGA Sbjct: 7574 SAAYNIPIVVTLSGDLDVGALNSALTDVLARHESLRTMFPVR----GDWPVQQILPAAGA 7629 Query: 693 VGARECLR-TVDALTDDV--LVEARNRLDPAAGAMVSAVWVRETSQ-LVLMIHHLAVDGV 748 V A + T + + D+V LV A + + T L +++HH++ DG Sbjct: 7630 VPALIPVTVTEEHVRDEVSRLVSAGFDVTVELPLRAGLYSLSATEYVLAVVVHHISADGF 7689 Query: 749 SWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFARW 782 S L+ D+ A+ +G + + LP +A W Sbjct: 7690 SMGPLVRDVMAAYGARASGAAPDWAPLPVQYADYALW 7726 Score = 420 bits (1079), Expect = e-114 Identities = 255/579 (44%), Positives = 333/579 (57%), Gaps = 28/579 (4%) Query: 22 DQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAH 81 D+ E+ P P P L PD+VAL DR +YRELDE SNR A Sbjct: 7997 DETELRAMAPARGGPDVRPQLWPDLLTAAAAFDPDSVALSYEDRRVSYRELDEWSNRWAR 8056 Query: 82 VLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVA 141 +L G P VA +PRS E++++I S+ K GAA++PVDP +P RI +M++D + Sbjct: 8057 ILRGRGVGPETFVAVGMPRSIESVVAIWSITKAGAAFVPVDPTYPRERIDYMLTDCRAAL 8116 Query: 142 ALTTADLRSRL----------DQYDLAVIDMADPA----IDRRPSDALSGPRPDDLAYMT 187 LT R L D+ A + PA DR L+ P AY+ Sbjct: 8117 GLTVRSRRGDLPDTVPWLMLDDEEVTAQVAAVSPAPVTDADRTGPLHLAHP-----AYLI 8171 Query: 188 YTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHG 247 YTSG+TG PK V VTH + + H SQ S FD SV+E+ A Sbjct: 8172 YTSGSTGRPKGVTVTHRGMADFTAETHERFQVSHESRVSQLASPSFDASVFELMMAFSAS 8231 Query: 248 GRLVVVPESV-GSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLI-VAGEACPT 305 ++V+VP +V G S +L +L E+V+ TP+A L +GL++ ++ + GEACP Sbjct: 8232 AQVVIVPPAVLGGS--ELADLFRREQVTHATITPTALAALDNDGLDALRVLDLVGEACPP 8289 Query: 306 ELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAP 365 E+V RWAPGR + + YGPTE TI A++S P+ L VLD+ L+P P Sbjct: 8290 EVVARWAPGRSLHSGYGPTETTIQASVSAPMRPGESVNIGSPALGFAFL-VLDERLQPVP 8348 Query: 366 EGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLG 425 GV GELY+AG G A GY RPDLT+ RFVAC FGE G RMYRTGD+VRW D LEYLG Sbjct: 8349 AGVPGELYIAGPGTARGYHNRPDLTSERFVACNFGEPGCRMYRTGDVVRWRRDHTLEYLG 8408 Query: 426 RADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITG----TADPA 481 R+D QVK+RG+RIELGEI A L + V A + GD L Y+ G PA Sbjct: 8409 RSDFQVKVRGFRIELGEIDAVLGRHPAVAFAATVGHTGPSGDTVLASYVRGHDGQEVQPA 8468 Query: 482 QLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQI 541 LRT AE LPA+MVP+AVVVLD IP+T GKLDR+ALPAPE+ S +RAP+T E+I Sbjct: 8469 GLRTYAAERLPAHMVPSAVVVLDRIPMTPVGKLDRKALPAPEFGSTGAAFRAPATETERI 8528 Query: 542 LADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA 580 + DV+A VLG++RVG DSFFDLGG+S+L+ ++V+ +A Sbjct: 8529 VVDVFASVLGLDRVGTADSFFDLGGNSLLATRIVSALQA 8567 Score = 409 bits (1052), Expect = e-111 Identities = 349/1128 (30%), Positives = 500/1128 (44%), Gaps = 109/1128 (9%) Query: 1045 RLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLF 1104 R FEA R G P+D P + QR+ D + PL+ QQ L F Sbjct: 1264 RTLFEAPTVEALAERIGSAHTRPAD-RPDLVAQRRPDRI----------PLSLAQQRLWF 1312 Query: 1105 HSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLT 1164 + + Y + + + +TG LD+ LR AV ++ RH +L + P QV+ Sbjct: 1313 VNQY--DTSSPAYNIPMALRLTGTLDEAALRTAVGDILGRHESLRTVYPASVDGPHQVIL 1370 Query: 1165 --ADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFV 1222 D M A + D+ + +L A D+ R AL RT G H V Sbjct: 1371 PLGDVMPALEPT-IVDDEAALRAQTVELAARG----FDVSTEAPVRGALFRT-GQAHVLV 1424 Query: 1223 LTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNFVNWLXXXXXXXXXXX 1275 L HHI DG SL L +++ Y P Y ++ W Sbjct: 1425 LVVHHISADGASLAPLARDLMVAYSARVRQQPPDWRPLPVQYADYSLWQRAALGSEDHPG 1484 Query: 1276 ---------WREVLDGFETPTLVAPPGVPGPRGIES--------YRVSAETTRALGELAR 1318 W+ L G P ++ P + PR + + VSAE R+L LAR Sbjct: 1485 SVMSAQVEYWKRTLSGL--PDVIDLP-LDRPRPTDRTLRGETVRFTVSAEDHRSLLLLAR 1541 Query: 1319 SQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKV 1378 T+ V+ A L+ R++G DVA GT ++GR + + +VG+L+NT+ +R V Sbjct: 1542 QHDCTMFMVMHAVLAVLIARLSGSGDVAIGTPIAGRGEE--ALDDVVGMLVNTLVLRTAV 1599 Query: 1379 SADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHV------SGHEQLFDTLFLYESYP--- 1429 T D+L ++ H + + + + LF L +++ Sbjct: 1600 EPAATFADVLALVREADLAAFGHADVPFESVVDAVAPTRSTAYSPLFQILLEFQNTAPVH 1659 Query: 1430 ----------IDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDV 1479 +D + +L +T E + + A Y + VFD Sbjct: 1660 VDLPGLTVETVDVEPGVAKFDLQLTLAEQYEKSDTAAGIAA--------SFTYASDVFDR 1711 Query: 1480 SEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDER-TQLDEW--ANRAVLTQPVDSPQS 1536 + +RF R+L + DPA + ++V+ ER + W +RAV S Sbjct: 1712 ATAAGFGERFVRILGTIAGDPATVVGDVEVLGPGERGLVVGSWNATSRAV------PGVS 1765 Query: 1537 IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSA 1596 + ++F QV R P APAV L+YGE +LA L G P SV + V RS Sbjct: 1766 VADLFVAQVGRSPGAPAVVCGEVVLSYGEFAARVYRLARWLIGEGVGPESSVGVAVRRSV 1825 Query: 1597 DAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEV 1656 D +V + AV+ G A++PIDP P R+ +++G A PV +TT F G ++VV V Sbjct: 1826 DMVVGVYAVVVAGGAFVPIDPDQPVERVGYVVGTAAPVLVLTTSADVGVFAG-SVRVVAV 1884 Query: 1657 DDPAVE------IYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAE 1710 D+ V + L P Y+++TSG+TG PKGV++ H + L + Sbjct: 1885 DELDVSGLGAGPVGDGERLARLRPGCPGYVMFTSGSTGRPKGVSVPHAGIVNRLLWMQDR 1944 Query: 1711 LPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVL 1770 G V Q + FDVSVWE++ L+ G RLVI P L L+V V + Sbjct: 1945 YRLGSDDVVLQKTPVTFDVSVWELFWPLVVGARLVIARPDGHRDPGYLADLIVEHRVTTV 2004 Query: 1771 YQTPS--AVRMMSPEGLEGTAL---VVAGEACPTEVVDRW---AVDRVMINAYGPTESTI 1822 + PS AV P T L +GEA P R + + N YGPTE+++ Sbjct: 2005 HFVPSMLAVFTAEPTAARCTGLRRVFASGEALPAATAARMRELVPEGGIHNLYGPTEASV 2064 Query: 1823 YAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXX 1882 VVPIG+PV T VLD LRPVP GV GELYL Sbjct: 2065 DVTFHEVTDADRVVVPIGAPVWNTQTVVLDGRLRPVPVGVAGELYLGGVQLARGYVGRAE 2124 Query: 1883 LTGTRFVACPFGEP---GARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQA 1939 LT RFVA PFG G+R+YRTGD VRW G+L+YLGR D QVK+RG R+ELGE++A Sbjct: 2125 LTAERFVANPFGAGDGRGSRLYRTGDRVRWLRSGELEYLGRTDFQVKLRGQRVELGEVEA 2184 Query: 1940 ALSDVDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAAARSELTNRLPAYMVPAAVV 1995 L V QAVV+ R D + L GY+ A D A R + +P +MVP+ VV Sbjct: 2185 VLLRRVEVAQAVVVLRGDGAAGEYLAGYVVPVAGAVVDERAVRESVAAVVPGFMVPSVVV 2244 Query: 1996 TLETLPLTVNGKLDRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVERXXXXXXX 2054 L LP+TVNGKLDR+ALP P++ S + AP T E+ +A + A +LG++R Sbjct: 2245 VLAELPVTVNGKLDRKALPTPDFGSPDSGFVAPRTPIEEIVAAVCADLLGLDRVGAHDNF 2304 Query: 2055 XXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 A R+ A +N + + +R +F+APTVA L+ E G Sbjct: 2305 FDLGGNSLIATRLVARINAVVGDRIGLRDVFDAPTVAGLAQLAESQDG 2352 Score = 368 bits (945), Expect = 6e-99 Identities = 274/826 (33%), Positives = 397/826 (48%), Gaps = 69/826 (8%) Query: 41 VTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPR 100 V++ LF QV R+P A A+V G+ +Y E RLA L G P ++V + R Sbjct: 4355 VSVADLFVAQVGRSPGAPAVVCGEVVLSYGEFAARVYRLARWLIGEGVGPESSVGVAVRR 4414 Query: 101 SGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTT-ADLRSRLDQYDLAV 159 S + ++ + +V+ G A++P+DP P R+G+++ A PV LTT AD+ + Sbjct: 4415 SVDMVVGVYAVVVAGGAFVPIDPDQPVERVGYVVGTAAPVLVLTTSADVGVFAGSVRVVA 4474 Query: 160 IDMADPA-IDRRP---SDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHA 215 +D D + + P + L+ RP Y+ +TSG+TG PK V+V H + + + Sbjct: 4475 VDELDVSGLGAGPVGDGERLARLRPGCPGYVMFTSGSTGRPKGVSVPHAGIVNRLLWMQD 4534 Query: 216 DLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSV 275 G V Q + FDVSVWE++ L+ G RLV+ P L ++ E V+ Sbjct: 4535 RYRLGSDDVVLQKTPVTFDVSVWELFWPLVVGARLVIAEPGGHRDPAYLERVIREESVTT 4594 Query: 276 LCQTPSAAGML----SPEGLESTTLI-VAGEACPTELVDRW--APGRVMINAYGPTEATI 328 + PS + + EG + + +GEA P+ R G + N YGPTEA++ Sbjct: 4595 VHFVPSMLEVFLAGANVEGCGALRRVFTSGEALPSASAARLRRVSGTELHNLYGPTEASV 4654 Query: 329 YAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPD 388 E VLD LRP P GV GELY+ G +A GY+GR + Sbjct: 4655 DVTFHEVTDADRVVVPIGAPVWNTQTVVLDGRLRPVPVGVAGELYLGGVQLARGYVGRAE 4714 Query: 389 LTASRFVACPFGE---TGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQA 445 LTA RFVA PFG G R+YRTGD VRW G+LEYLGR D QVK+RG R+ELGE++A Sbjct: 4715 LTAERFVANPFGAGDGRGSRLYRTGDRVRWLRSGELEYLGRTDFQVKLRGQRVELGEVEA 4774 Query: 446 ALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAQLRTALAESLPAYMVPTAVV 501 L + V QAVV+ R D + L GY+ A D +R ++A +P +MVP+ VV Sbjct: 4775 VLLRRVEVAQAVVVLRGDGAAGEYLAGYVVPVAGAVVDERAVRESVAAVVPGFMVPSVVV 4834 Query: 502 VLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSF 561 VL +P+TVNGKLDR+ALP P++ + YR P+TPAE+ +A +A VLG++RVG DDSF Sbjct: 4835 VLAELPVTVNGKLDRKALPTPDFGTTTRGYRVPTTPAEEAVASAFAAVLGIDRVGADDSF 4894 Query: 562 FDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXX-ESHVVDEGVGPVV 620 DLGGDS+ + + V R +A D+ V +S V+ P + Sbjct: 4895 LDLGGDSLSATRAVGRINSA----LDTDLGVAALFDAPVVADLAARIDSDVMTSSTSPAL 4950 Query: 621 -------------ATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHA 667 A M ++ + D + +N V Q + D + L +L+RH Sbjct: 4951 TARPRPERIPLSLAQQRMWFVNQFDTASPAYNIPVALQLDGALDLDALRAALGDVLERHE 5010 Query: 668 TLRLRVEDTQEDTDEW---SLLV-----PEAGAVGA-RECLRTVDA----LTDDVLVEAR 714 +LR + + + S LV P A GA RE L +T+DV + R Sbjct: 5011 SLRTVFPGSADGPRQMIADSALVTPGLEPVPVAEGALRESLTAFFGAGFDVTEDVPIRVR 5070 Query: 715 N-RLDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQS---I 770 RL P E L L++HH+A DG S L D+ +A+ G + Sbjct: 5071 LVRLAP------------ERHVLALVVHHIAADGFSMAPLARDVMLAYTARAQGHAPGWA 5118 Query: 771 ELPAGGTSFARW--SALLAEHAKTDTVRDLADAW-RAVTSVPQALP 813 LP + W AL + + L W R ++ +P LP Sbjct: 5119 PLPVQYADYGLWQREALGTDEQPDSMISGLLGYWTRTLSGIPDVLP 5164 Score = 355 bits (911), Expect = 5e-95 Identities = 260/791 (32%), Positives = 383/791 (48%), Gaps = 63/791 (7%) Query: 41 VTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPR 100 V++ LF QV R+P A A+V G+ +Y E RLA L G P ++V + R Sbjct: 1764 VSVADLFVAQVGRSPGAPAVVCGEVVLSYGEFAARVYRLARWLIGEGVGPESSVGVAVRR 1823 Query: 101 SGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTT-ADLRSRLDQYDLAV 159 S + ++ + +V+ G A++P+DP P R+G+++ A PV LTT AD+ + Sbjct: 1824 SVDMVVGVYAVVVAGGAFVPIDPDQPVERVGYVVGTAAPVLVLTTSADVGVFAGSVRVVA 1883 Query: 160 IDMADPA-IDRRP---SDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHA 215 +D D + + P + L+ RP Y+ +TSG+TG PK V+V H + + + Sbjct: 1884 VDELDVSGLGAGPVGDGERLARLRPGCPGYVMFTSGSTGRPKGVSVPHAGIVNRLLWMQD 1943 Query: 216 DLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSV 275 G V Q + FDVSVWE++ L+ G RLV+ P L +L++ +V+ Sbjct: 1944 RYRLGSDDVVLQKTPVTFDVSVWELFWPLVVGARLVIARPDGHRDPGYLADLIVEHRVTT 2003 Query: 276 LCQTPSAAGMLSPEGLESTT-----LIVAGEACPTELVDRW---APGRVMINAYGPTEAT 327 + PS + + E + + +GEA P R P + N YGPTEA+ Sbjct: 2004 VHFVPSMLAVFTAEPTAARCTGLRRVFASGEALPAATAARMRELVPEGGIHNLYGPTEAS 2063 Query: 328 IYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRP 387 + E VLD LRP P GV GELY+ G +A GY+GR Sbjct: 2064 VDVTFHEVTDADRVVVPIGAPVWNTQTVVLDGRLRPVPVGVAGELYLGGVQLARGYVGRA 2123 Query: 388 DLTASRFVACPFGE---TGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQ 444 +LTA RFVA PFG G R+YRTGD VRW G+LEYLGR D QVK+RG R+ELGE++ Sbjct: 2124 ELTAERFVANPFGAGDGRGSRLYRTGDRVRWLRSGELEYLGRTDFQVKLRGQRVELGEVE 2183 Query: 445 AALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAQLRTALAESLPAYMVPTAV 500 A L + V QAVV+ R D + L GY+ A D +R ++A +P +MVP+ V Sbjct: 2184 AVLLRRVEVAQAVVVLRGDGAAGEYLAGYVVPVAGAVVDERAVRESVAAVVPGFMVPSVV 2243 Query: 501 VVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDS 560 VVL +P+TVNGKLDR+ALP P++ S + + AP TP E+I+A V A +LG++RVG D+ Sbjct: 2244 VVLAELPVTVNGKLDRKALPTPDFGSPDSGFVAPRTPIEEIVAAVCADLLGLDRVGAHDN 2303 Query: 561 FFDLGGDSILSMQVVARARA-AGIQCRPRDIFVEQTXXXXXXXXXXXXESHV-----VDE 614 FFDLGG+S+++ ++VAR A G + RD+F T E Sbjct: 2304 FFDLGGNSLIATRLVARINAVVGDRIGLRDVFDAPTVAGLAQLAESQDGLEARPPLKPRE 2363 Query: 615 GVGPVVATPI---MRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRL 671 G V +P M ++ + D + +N + L+ LD HA L+ Sbjct: 2364 GTAEVPVSPAQQRMWFINQFDTSSSAYNVAFALR-------------LEGRLDVHA-LQA 2409 Query: 672 RVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTD--DVLVEARNRLDPAAGAMVSAVW 729 V D E + L P A + L +A+ D V+V L + ++SA + Sbjct: 2410 AVADVVERHEAVRTLFPLADDGPRQVVLPAANAVPDLAPVVVPGEAELREHSLILLSAGF 2469 Query: 730 VRETS---------------QLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQS---IE 771 T L +++HH+A DG S L D+ A+ G + + Sbjct: 2470 DVTTQVPLRAKLFRLDENLHVLAVVVHHIAADGFSMAPLARDVMAAYVSRSNGSAPDWLP 2529 Query: 772 LPAGGTSFARW 782 L +A W Sbjct: 2530 LDVQYADYALW 2540 Score = 59.3 bits (142), Expect = 8e-06 Identities = 155/715 (21%), Positives = 243/715 (33%), Gaps = 101/715 (14%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 + + G LD LR V + + VE G P+Q + + ++D RGD Sbjct: 46 VELHGDLDIGLLRRETIAVAREFESPFLKVVEVDGTPMQYVDHSTDTSIEFVDFRGDQ-N 104 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 P + A DL F +++ + + HH+ +DG+ L+ I Sbjct: 105 PVAAAHAWMDRDYQAPLDLAADRLFETSILCVGEAHYLWYSRIHHVALDGYGAMTLINRI 164 Query: 1243 FAGYFGHRLPAA---------------APYRNFVNWLXXXXXXXXXXXWREVLDGFETPT 1287 HR AA A Y + W ++G T Sbjct: 165 -----AHRYSAAVAGREPDPSRAATLRALYDVDAGYRASDRFVADREYWAGRVEGIGGST 219 Query: 1288 LVAPPGVPGPRG-IESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVA 1346 L R +ES +S + T + AA+ L R T + +V Sbjct: 220 LADADAPALARSKVESALLSEAAASGIQNSDSQATATAAVTIIAAFACYLSRATAKTEVL 279 Query: 1347 FGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLAL 1406 +SGR L + G+ + P+ V D TV DL+ +++ L H+ ++ Sbjct: 280 VNVPMSGRTTSLL--RNSGGMTVTVAPLPVTVDEDGTVADLVARVRRELMGALRHQRCSV 337 Query: 1407 NDIHHVSG-------HEQLFDTLFLYE---------SYPIDTSAFMGVQELAVTEFNNRE 1450 DI +G H + + + ++ Y I TS V++L V Sbjct: 338 EDIRRDAGAGGGAELHGPMVNVMLFHQEVTLGPLVGEYHIVTSG--PVEDLLV------- 388 Query: 1451 YNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMID-DPARRLSSM-D 1508 N YP A E+ + + + ++ S + F LLE + DP RL ++ D Sbjct: 389 -NVYPSGTPA----EIFVDFRANPNRYEDSALRRHHRHFVELLEEFVSADPQARLGTVHD 443 Query: 1509 VVDDDERTQLDEWANRAVLTQPVDSPQSIPEVF------ARQVERDPEAPAVTFE-GESL 1561 D + E + A T D +PEV R + R V G Sbjct: 444 ATARDGARRRREALHLAYWT---DRLSGMPEVLNLPSDRVRPILRSGRGDRVDVPIGAGT 500 Query: 1562 NYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPA 1621 + G A + L V AA A+L +GAA + + VP Sbjct: 501 HRGVRALAEDHDTTLFGVLHAA----------------AAVLLSRLSGAADVAVGTMVPV 544 Query: 1622 ARLE--FMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPD-DIA 1678 R + +L P+ A T LR D D + E D E L SP Sbjct: 545 DRGQNLVVLRTRAPLDATFTEHLR-YVDAVDREAFEHRDVPFEHVVRAVALRDSPAFSPI 603 Query: 1679 YMIYTSGTTGVPKGVAITHGNVTQVLDTLPAE-LPAGPGAVWSQWHSLVFDVSVWEIWGA 1737 + G P G+ VT +T A+ LPAG +L F V +++ Sbjct: 604 VQVLVDGDAAGPPGIGRFDLRVT-AAETFDADGLPAGITV------TLGFAVDLFDPGTV 656 Query: 1738 LLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA--VRMMSPEGLEGTAL 1790 G R + E+ G P +V +++L A V + P G G AL Sbjct: 657 RRLGERFRRILEAATGDPG-----VVVGDIDILSDAERATLVPVPGPAGRPGRAL 706 >tr|Q9ZET7|Q9ZET7_MYCSM Tax_Id=1772 (peptide synthetase)SubName: Full=Peptide synthetase; Flags: Fragment;[Mycobacterium smegmatis] Length = 1438 Score = 1358 bits (3515), Expect = 0.0 Identities = 688/1025 (67%), Positives = 789/1025 (76%), Gaps = 6/1025 (0%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P+ L + LL E E D++ GN + L++ P V+IP FA +V APDA AL Sbjct: 420 MAADPAM-PLAAVRLLAESESDRLATIGNHSALSESAPDAVSIPERFAARVAEAPDAAAL 478 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 R+ TYRELDEA+NR AH L G PG+ VA + PR+ ++++IL K GAAY+P Sbjct: 479 TFEGRTLTYRELDEAANRFAHALLARGIGPGSRVALMSPRTDRSVIAILGAFKAGAAYVP 538 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VDPA P AR+ F++ DA PVA +TTA+LRSR D +DLAVID+ DPAI P+ A+S PRP Sbjct: 539 VDPAVPAARVRFILDDASPVAVVTTAELRSRFDGHDLAVIDIDDPAIASLPATAVSDPRP 598 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DD+AY+ YTSGTTG PK VAVTH N+T L++ L LP PG VW HSL FD SVWEI Sbjct: 599 DDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVLEERLPK-PG-VWPLCHSLAFDASVWEI 656 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG 300 ALL GGRLVVVPE+V SP+D H+LL+ E+V+ L QTPSA MLSP+GLES TL V G Sbjct: 657 SNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQVTFLTQTPSAVAMLSPDGLESMTLAVVG 716 Query: 301 EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 EACP LVDRWA R MINAYGPTE TI S PL LFVLD W Sbjct: 717 EACPPALVDRWATNRTMINAYGPTETTICVTSSSPLEPGSVVVPIGSALPRTALFVLDPW 776 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 LRP P GV GELYVAG GV GYIGR LTASRFV CPFGE G RMYRTGDLVRWG DGQ Sbjct: 777 LRPVPTGVAGELYVAGDGVTCGYIGRSGLTASRFVPCPFGEPGARMYRTGDLVRWGRDGQ 836 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 LEYLGRADEQVKIRGYRIELGE+Q+ALA LDGV+ A I REDRPGD+RLVGYITGTADP Sbjct: 837 LEYLGRADEQVKIRGYRIELGEVQSALAALDGVESAAAIMREDRPGDRRLVGYITGTADP 896 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 +R LA+ LP YMVPTA+VVL +PLT + KLD RALPAPEY +A +YRAPS P E+ Sbjct: 897 VDIRAELADRLPPYMVPTAIVVLPALPLTSSNKLDTRALPAPEYANAEKNYRAPSNPVEE 956 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXX 600 +LAD+YAQVLGVER+GVDDSFFDLGGDSILSMQVVARARAAGIQCRPRD+FVEQT Sbjct: 957 VLADIYAQVLGVERIGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDVFVEQTVARLA 1016 Query: 601 XXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQ 660 E VVD+G G TPI+ WLRE G T +FNQT++ QAP GVTE DVV +LQ Sbjct: 1017 SVATVATEIGVVDDGTGSAAPTPIIHWLREAGGATDEFNQTLVVQAPTGVTEPDVVAVLQ 1076 Query: 661 ALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPA 720 ALLDRHATLRLRV+D+ EWSLLVP+A V AR+CL VD L+DDV++ AR +L+PA Sbjct: 1077 ALLDRHATLRLRVQDSD---GEWSLLVPDAATVDARDCLSVVDTLSDDVVLAARAKLNPA 1133 Query: 721 AGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 780 AGAMVSA+WVR+TSQLVL+IHHLAVDGVSWRILLEDLNIAWAQH +GQ ++LPAGGTSF Sbjct: 1134 AGAMVSALWVRQTSQLVLIIHHLAVDGVSWRILLEDLNIAWAQHHSGQQVQLPAGGTSFL 1193 Query: 781 RWSALLAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL 840 RWS LA+HA T V ADAWR + + P ALP VQPDTDT+ +AG+ SA+LD ETTRQL Sbjct: 1194 RWSKRLADHAHTAEVTAQADAWREILAKPAALPAVQPDTDTHASAGRFSATLDPETTRQL 1253 Query: 841 LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGW 900 LGEVPAAF AGVQDILLVAFGLAW EFLNRS TPI VDVEGHGR++ELASD+DLSRTVGW Sbjct: 1254 LGEVPAAFHAGVQDILLVAFGLAWAEFLNRSGTPITVDVEGHGRHEELASDIDLSRTVGW 1313 Query: 901 FTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEVDLGG 960 FTTKYPVALTV ++PW QVVAG+A LG +VK VKEQLR++P+GLTYGLLRYLN EV+LGG Sbjct: 1314 FTTKYPVALTVADVPWAQVVAGEATLGAVVKDVKEQLRAVPDGLTYGLLRYLNSEVELGG 1373 Query: 961 SDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDN 1020 ++PTIGFNYLGRLGAGAGELSEELWRI+Q VPMPL HTVELNAGT+DTD Sbjct: 1374 TEPTIGFNYLGRLGAGAGELSEELWRIEQGSLALTDVVSAVPMPLAHTVELNAGTMDTDK 1433 Query: 1021 GPSLR 1025 GPSL+ Sbjct: 1434 GPSLQ 1438 Score = 696 bits (1795), Expect = 0.0 Identities = 426/988 (43%), Positives = 552/988 (55%), Gaps = 27/988 (2%) Query: 1125 ITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD 1184 I GV+D L+ A+ + A F E G+ Q + D+R D P+ Sbjct: 38 IDGVVDHGLLQQAIRQALQEAEPARATFFEADGQVFQKPLDYSELEVPLYDVRDAD-DPE 96 Query: 1185 HEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFA 1244 + ++ A + L R + AL +T Q HHI +DG + ++ + I Sbjct: 97 AKAREMAAEIQHTPLPLTGR-LVKFALFQTRDEQFYLFGLGHHISVDGLGMALVSRRIST 155 Query: 1245 GYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG-------VPGP 1297 Y P F + + D + PP P P Sbjct: 156 IYTSLVTGKPVPEAYFGSLRDLVECEMSYESSADYQDDLAYWSENLPPDTGLDQGLAPTP 215 Query: 1298 RGIESYRVSAET------TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRD-VAFGTA 1350 G +Y SA + EL+++ +V AA L + D VA Sbjct: 216 HGKNAYTPSASVPMDPAIVGRIKELSKTLRIRRYSVTTAACALLAQSWSSTGDQVALDFP 275 Query: 1351 VSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHL---ALN 1407 VS R + ++++ +L P+ TVG+ + + + L+H+ L Sbjct: 276 VSRRVS--PESKTLPAMLAGVAPLVLDAPPQLTVGEFCKHVDIRIRELLQHQRFPVHRLG 333 Query: 1408 DIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELG 1467 D + G Q + L + T F G E + N+ H+ L + G EL Sbjct: 334 DGGALRGPRQASNRLAVNFIPSRLTLDFAGA-EATASYTNHGPMGHFGLFFIG-AGEELF 391 Query: 1468 LRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 L F E+ L +R ++ AM DPA L+++ ++ + E +L N + L Sbjct: 392 LSTAGAGQPFANFEVPELAERLGAIVAAMAADPAMPLAAVRLLAESESDRLATIGNHSAL 451 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 ++ SIPE FA +V P+A A+TFEG +L Y ELDEAAN+ A+ L G PG Sbjct: 452 SESAPDAVSIPERFAARVAEAPDAAALTFEGRTLTYRELDEAANRFAHALLARGIGPGSR 511 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VALM PR+ +++AIL K GAAY+P+DP+VPAAR+ F+L DA PVA VTT +LRSRFD Sbjct: 512 VALMSPRTDRSVIAILGAFKAGAAYVPVDPAVPAARVRFILDDASPVAVVTTAELRSRFD 571 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 G DL V+++DDPA+ P+T + P PDDIAY+IYTSGTTG PKGVA+TH N+T ++ L Sbjct: 572 GHDLAVIDIDDPAIASLPATAVSDPRPDDIAYVIYTSGTTGTPKGVAVTHKNLTHLIAVL 631 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 LP PG VW HSL FD SVWEI ALL GGRLV+VPE++AGSP+D H LLV+E V Sbjct: 632 EERLPK-PG-VWPLCHSLAFDASVWEISNALLRGGRLVVVPEAVAGSPEDFHDLLVAEQV 689 Query: 1768 NVLYQTPSAVRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAIS 1827 L QTPSAV M+SP+GLE L V GEACP +VDRWA +R MINAYGPTE+TI S Sbjct: 690 TFLTQTPSAVAMLSPDGLESMTLAVVGEACPPALVDRWATNRTMINAYGPTETTICVTSS 749 Query: 1828 APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTR 1887 +PL PGS VVPIGS +P+ A FVLD WLRPVP GV GELY+A LT +R Sbjct: 750 SPLEPGSVVVPIGSALPRTALFVLDPWLRPVPTGVAGELYVAGDGVTCGYIGRSGLTASR 809 Query: 1888 FVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGV 1947 FV CPFGEPGARMYRTGDLVRWG DGQL+YLGRADEQVKIRGYRIELGE+Q+AL+ +DGV Sbjct: 810 FVPCPFGEPGARMYRTGDLVRWGRDGQLEYLGRADEQVKIRGYRIELGEVQSALAALDGV 869 Query: 1948 DQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGK 2007 + A I REDRPGD+RLVGYITGTADP R+EL +RLP YMVP A+V L LPLT + K Sbjct: 870 ESAAAIMREDRPGDRRLVGYITGTADPVDIRAELADRLPPYMVPTAIVVLPALPLTSSNK 929 Query: 2008 LDRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMR 2066 LD RALPAPEY +A++ YRAP E+ LA I+A VLGVER +M+ Sbjct: 930 LDTRALPAPEYANAEKNYRAPSNPVEEVLADIYAQVLGVERIGVDDSFFDLGGDSILSMQ 989 Query: 2067 VTAAVNTALDADLSVRTLFEAPTVAKLS 2094 V A A R +F TVA+L+ Sbjct: 990 VVARARAA-GIQCRPRDVFVEQTVARLA 1016 >tr|D2B247|D2B247_STRRD Tax_Id=479432 SubName: Full=Non-ribosomal peptide synthase;[Streptosporangium roseum] Length = 4106 Score = 1357 bits (3511), Expect = 0.0 Identities = 909/2224 (40%), Positives = 1172/2224 (52%), Gaps = 223/2224 (10%) Query: 12 SFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRE 71 + DLLDE E + WG A P T VT LF EQV R P+AVA+V+GD TY E Sbjct: 418 AIDLLDEAERALLGDWGG-APREVPDGTAVT---LFEEQVRRRPEAVAVVAGDTEVTYAE 473 Query: 72 LDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPV---------- 121 L+ +NRLAH L GA P V +PRS + +++ L++LK+GAAYLP+ Sbjct: 474 LNVRANRLAHHLIARGAGPDRYVGLSVPRSLDMVVAFLAILKSGAAYLPLDPDYPRDRLA 533 Query: 122 ----DPAHP-------------------DARIGFMMSDAKPVAALTT------------- 145 D A P DAR G ++ A A Sbjct: 534 VMLADAAPPIVVTCAAAGLLPPPGADTVDARTGESLAGAGAGAGAGAGAGDGGGSGDGGG 593 Query: 146 ---ADLRSRLDQYDLAVIDMADPAIDRRP-SDALSGPRPDDLAYMTYTSGTTGVPKAVAV 201 A R V+ M D P SD ++ P AY+ +TSG+TG+PK V V Sbjct: 594 AGRAGTRIEDGLSGAEVVMMDTWTGDGLPGSDPVTALLPGHPAYVVFTSGSTGLPKGVLV 653 Query: 202 THHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESV-GSS 260 TH + Q+ S+ FD +V E A G LV+ P V G Sbjct: 654 THAGLPGYARTEIDRYAVTEDSRVLQFASIGFDGAVLEWLMAFSSGAALVLAPAGVYGGE 713 Query: 261 PDDLHNLLITEKVSVLCQTPSAAGMLSPEGL-ESTTLIVAGEACPTELVDRWAPGRVMIN 319 P L L +V+ TP+A + L + TL+V GEAC ELV RW+ GR MIN Sbjct: 714 P--LGRFLAETRVTHAFITPAALATIPERPLPDLRTLLVGGEACRPELVRRWSAGRRMIN 771 Query: 320 AYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGV 379 YGPTE T+ A S+PL L VLD LRP P G GELYVAG V Sbjct: 772 VYGPTETTVVVATSDPLTSPDDTPIGRPVYDTR-LHVLDPGLRPVPPGTAGELYVAGPSV 830 Query: 380 ATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIE 439 A GY+ RP LTA RFVA P G G RMYRTGDLVRWG+DGQL+YL RAD QVK+RG+RIE Sbjct: 831 ARGYLNRPGLTAERFVADPTG-AGGRMYRTGDLVRWGADGQLQYLDRADRQVKVRGFRIE 889 Query: 440 LGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTA 499 LGEI++ LA GV QA V+AR+D+PGD+RLV Y+TGTAD +LR +LP YMVP A Sbjct: 890 LGEIESVLAGHPGVGQAAVLARDDQPGDRRLVAYVTGTADADELRRHARRALPDYMVPAA 949 Query: 500 VVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDD 559 +VVLD +PLT NGKLDRRALPAPE ++ R P+T E++L ++A+VLGVERVG DD Sbjct: 950 IVVLDAMPLTANGKLDRRALPAPERETSG---REPATDRERLLCALFAEVLGVERVGADD 1006 Query: 560 SFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVV-DEGVGP 618 FFDLGGDSIL++++VARAR AG+ P+ +F ++ E+ V D+GVG Sbjct: 1007 GFFDLGGDSILAIRLVARAREAGLGLTPKHVFQHRSPEALALVAHEAVETVVTGDDGVGA 1066 Query: 619 VVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQE 678 V ATPIM WL E GP FNQTV+ + P G+ D ++V +QA+LD H LRLRV Sbjct: 1067 VPATPIMAWLAERGGPIDGFNQTVVLRVPPGLGLDHLIVAVQAVLDCHDVLRLRVAGPGV 1126 Query: 679 DTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEA------RNRLDPAAGAMVSAVWV-- 730 L V G V A E +R V+ + A R LDP AG MV W+ Sbjct: 1127 S----GLEVMARGVVRAVEHVRRVEVAGEVEEAVAGQVELLRCGLDPVAGRMVGVAWLDA 1182 Query: 731 --RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAE 788 + +LVL +HHLAVDGVSWRILL DL AW G++ L TSF W+ L + Sbjct: 1183 GPEVSGRLVLTVHHLAVDGVSWRILLPDLFAAWEAAVQGKAPVLAPVPTSFRTWAHRLRD 1242 Query: 789 HAK-TDTVRDLADA---------WRAVTSVPQALPPVQPD-TDTYVTAGQLSASLDVETT 837 A+ RD DA W + P P T+ + L E T Sbjct: 1243 EARDRGEARDGGDAHDRTAELDRWTEILDGPAGDGSATPRWWGTWGERRETVVELPAEVT 1302 Query: 838 RQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRT 897 R LLG+VP AF D+LL GLA D + +D+EGHGR D A VDLSRT Sbjct: 1303 RPLLGKVPGAFHGRADDVLLA--GLAAAVARWSGDRSVLIDLEGHGREDVFAG-VDLSRT 1359 Query: 898 VGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNP--- 954 VGWFT YPV + + W + G ++ VK VKEQLR+LP+ L+YGLLRYLNP Sbjct: 1360 VGWFTAMYPVRIDAGPVDWSDLRNGGQSVAQAVKRVKEQLRALPDSLSYGLLRYLNPGTA 1419 Query: 955 EVDLGGSDPTIGFNYLGRLGAGAGELSEELWR-IDQXXXXXXXXXXXVPMPLMHTVELNA 1013 V P IGFNYLGR+ S + W PL H +E+NA Sbjct: 1420 PVLAALPRPEIGFNYLGRI-----TTSGQDWEPATDGPSGGLSGGQDAGAPLRHGIEINA 1474 Query: 1014 GTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPA 1073 + G +LR +WTW+P + E++ L+ W EAL GI H GGGLTPSDV A Sbjct: 1475 VAL----GDTLRVTWTWSPHHYTEDRIVELATAWSEALTGISRHT---GGGLTPSDVT-A 1526 Query: 1074 RLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHR 1133 RLTQ +D D+ D PL P+Q+GL FHS A DVY QL + +TG LD R Sbjct: 1527 RLTQDDLDGFGP--DLQDAWPLAPLQRGLFFHSMLA----VDVYTAQLVLDLTGPLDAAR 1580 Query: 1134 LRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAA 1193 LR A +V RHP L A F + G PVQ++ + WR + + + A Sbjct: 1581 LRTAAERLVRRHPGLRASFEFRDG-PVQLVHRRVEVPWREV--------ATADAAGVAAE 1631 Query: 1194 ERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPA 1253 ER+ DL P R AL+R + +H+ +LT HHI++DGWS P+L E+FA Y G A Sbjct: 1632 ERAHRFDLSRPPLLRFALVRLAPGRHQLILTNHHILLDGWSTPLLAAELFALYTGDEPSA 1691 Query: 1254 AAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAP--PGVPGPRGIESYRVSAETTR 1311 A PY+ ++ WL W LDG + PTLVAP P P P G + ++ TR Sbjct: 1692 APPYKGYLEWLARQDHAAATAAWDRALDGLDDPTLVAPHAPADPVPPGRVTAELADGPTR 1751 Query: 1312 ALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINT 1371 AL LAR+ TT+NTV+QAA+ LL ++TG DV FG VSGRP +L G E MVGL INT Sbjct: 1752 ALTTLARTHSTTLNTVMQAAFGLLLAQLTGGDDVVFGGTVSGRPPELPGVERMVGLFINT 1811 Query: 1372 VPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPID 1431 +P+R ++ VGDLLR+L+ + L H HL L++I LFDTL + E+YP+D Sbjct: 1812 LPVRVRLRPAEPVGDLLRRLRDEQAELLAHHHLGLSEIR----RGVLFDTLLVMENYPLD 1867 Query: 1432 TSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQR 1491 +G +L +T + + HYP++++ +PG L R++Y VF E E L+DRF+ Sbjct: 1868 PRTTIG--DLRLTSADVADATHYPITLLVIPGERLRFRLQYRPDVFTEEEAEGLLDRFRH 1925 Query: 1492 LLEAMI---DDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERD 1548 LL + D P RL + D+ L EW + A V ++ +F QV R Sbjct: 1926 LLTTLAAAPDTPVGRLGGL--FRDERELLLREWNDTAAAVPEV----TLAGLFEEQVART 1979 Query: 1549 PEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKT 1608 P+A A+ EG L+Y + AN+LA LLA + A P + VALM+PRS D +VA+ AV+K Sbjct: 1980 PDATALVSEGVELSYAAFNARANRLARLLAEHEAGPERVVALMLPRSPDLLVAMYAVVKA 2039 Query: 1609 GAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTT 1668 GAAYLPIDP +PA R+ ML DA+PV + L G D+ ++ V Sbjct: 2040 GAAYLPIDPGLPAGRIASMLDDARPVLVIDHDWLA----GADVSGCSAENLEVR------ 2089 Query: 1669 LLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVL------------DTLPAELPAGPG 1716 P+PD+ AY+IYTSG+TG PKGV ++H ++ L D + + PAG Sbjct: 2090 ---PAPDNPAYVIYTSGSTGRPKGVVVSHRSIVNRLLWAQSRYGLRADDRVLQKTPAG-- 2144 Query: 1717 AVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPS- 1775 FDVSVWE + L G LVI P L L+ +E V ++ PS Sbjct: 2145 ----------FDVSVWEFFWPLQTGAALVIARPGGHRDPAYLAGLIDAERVTTVHFVPSM 2194 Query: 1776 -AVRMMSPEGLEGTAL---VVAGEACPTEVVDRWAVDRVMI---NAYGPTESTIYAAI-S 1827 AV + + +G +L + +GEA P EV D+ AV R+ + N YGPTE+ + Sbjct: 2195 LAVFLAASDGPAPASLRRVICSGEALPPEVADQ-AVARLGVPVHNLYGPTEAAVDVTYWE 2253 Query: 1828 APLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTR 1887 P VPIG PV +VLD WLRPVP GV GELYLA LT R Sbjct: 2254 HRPDPDGGSVPIGRPVWNTRVYVLDPWLRPVPVGVAGELYLAGVQLARGYLGRGGLTAER 2313 Query: 1888 FVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGV 1947 FVACPFG PG RMYRTGD+VRW DG L Y+GRAD QVK+RG+RIELGE++A L+ V Sbjct: 2314 FVACPFGGPGERMYRTGDVVRWRADGGLDYVGRADFQVKVRGFRIELGEVEAVLARHGSV 2373 Query: 1948 DQAVVIAREDRPGDKRLVGYIT---------------------------------GTADP 1974 V+ REDRPGD+RLV Y+ D Sbjct: 2374 SGVAVVVREDRPGDRRLVAYVVPAPAGPVEGDMLAVPARRAGGEAVAAPVGRVVPAEVDA 2433 Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKT 2034 A R + LP YMVP+ VV L+ LP+T NGKLDR ALP PE S R P + E+ Sbjct: 2434 AELRRWVGEVLPEYMVPSVVVVLDVLPVTRNGKLDRAALPVPEV-SVGSGRGPRSVVEEV 2492 Query: 2035 LAGIFAHVLGVER-XXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKL 2093 L G+FA VLG + MR+ + V + L +L VR +FEA +VA L Sbjct: 2493 LCGVFAEVLGFDGVVGVDDSFFDLGGDSLLVMRLVSRVRSVLSVELPVRVVFEASSVAAL 2552 Query: 2094 SLHV 2097 ++ V Sbjct: 2553 AVWV 2556 Score = 741 bits (1913), Expect = 0.0 Identities = 480/1141 (42%), Positives = 618/1141 (54%), Gaps = 84/1141 (7%) Query: 1 MTAEPSTRTLLSFDLLDEDE-HDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVA 59 +TA+P +L + D+LD E H + W + PG P TI F QV R+P AVA Sbjct: 2995 VTADPDV-SLSAIDILDARERHTILRDWAGTG--SSPG-VPSTIAEEFEAQVARSPHAVA 3050 Query: 60 LVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYL 119 +V +Y ELD + LA VL G P VA ++PRS E ++++++V+K G AY+ Sbjct: 3051 VVGSGVELSYGELDARAGALARVLVGLGVGPERFVALVVPRSVELVVAVVAVVKAGGAYV 3110 Query: 120 PVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPR 179 P+DP +P RI ++ DA+PV A+T L L + + I P A++G Sbjct: 3111 PIDPGYPADRIAHIVRDARPVLAVTVPGSEGLLPA-GLPRVVLDGSVITAVPDAAVAGGE 3169 Query: 180 -----PDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFD 234 P AY+ +TSG+TG PK V V H NVT+L+++ VW+ +HS FD Sbjct: 3170 VGRLVPAHPAYVIFTSGSTGRPKGVVVPHGNVTRLLASTEGWFGFDETDVWTLFHSYAFD 3229 Query: 235 VSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGML-----SPE 289 SVWE+WGALL+GGRLVVVP V SP + L+ V+VL QTPSA Sbjct: 3230 FSVWELWGALLYGGRLVVVPFEVSRSPGEFVALVAECGVTVLNQTPSAFYQFMRAERERA 3289 Query: 290 GLESTT--LIVAGEACPTELVDRWAPGR------VMINAYGPTEATI---YAAMSEPLXX 338 G+E + +I GEA +D W GR V++N YG TE T+ YAA+ Sbjct: 3290 GVELSLRCVIFGGEALDPGRLDDWY-GRHPETAPVLVNMYGITETTVHVTYAALDREAAV 3348 Query: 339 XXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACP 398 ++VLD++L P P GVVGELYVAG GVA GY+GR LTA RFVA P Sbjct: 3349 SGVGSVIGVGIPDLRVYVLDEFLCPVPPGVVGELYVAGAGVARGYVGRAGLTAERFVADP 3408 Query: 399 FGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVV 458 FG G RMYR+GDL RW G+LE+LGR D+QVKIRG+RIELGE++ L V A V Sbjct: 3409 FGVGGGRMYRSGDLARWDRAGRLEFLGRVDQQVKIRGFRIELGEVEGVLVGHPAVADAAV 3468 Query: 459 IAREDRPGDKRLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRA 518 + REDRPGD+RLV Y+ GTA P LR E+LP YMVP AVVVL+ +PLT NGKLDRRA Sbjct: 3469 VVREDRPGDRRLVAYVVGTATPDALRAWAREALPDYMVPAAVVVLEALPLTANGKLDRRA 3528 Query: 519 LPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARA 578 LP PE S+ R PSTP E +L ++A+VLGVERVG DD FFDLGGDSI+++Q+VARA Sbjct: 3529 LPVPEITSSG---REPSTPREALLCALFAEVLGVERVGADDGFFDLGGDSIIAIQLVARA 3585 Query: 579 RAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVVDE--GVGPVVATPIMRWLREVDGPTG 636 R AG+ PRD+F Q+ E+ E G+GP+ ATPIM WL E GP Sbjct: 3586 RQAGVVFGPRDVFRHQSVRELAAVATDGQETEHEPEGAGIGPLPATPIMAWLAERGGPID 3645 Query: 637 QFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGAR 696 FNQTV+ + P G+ D ++V +QA+LD H LRLRV L V G V A Sbjct: 3646 GFNQTVVLRVPPGLGLDHLIVAVQAVLDCHDVLRLRVAGPGVS----GLEVMARGVVRAA 3701 Query: 697 ECLRTVDALTDDVLVEA------RNRLDPAAGAMVSAVWV----RETSQLVLMIHHLAVD 746 E +R V+ + A R LDP AG MV W+ + +LVL +HHLAVD Sbjct: 3702 EHVRRVEVAGEVEEAVAGQVELLRCGLDPVAGRMVGVAWLDAGPEVSGRLVLTVHHLAVD 3761 Query: 747 GVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAK-TDTVRDLADA---- 801 GVSWRILL DL AW G++ L TSF W+ L + A+ RD DA Sbjct: 3762 GVSWRILLPDLFAAWEAAVQGKAPVLAPVPTSFRTWAHRLRDEARDRGEARDGGDAHDRT 3821 Query: 802 -----WRAVTSVPQAL---PPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQ 853 W + P L P+ P DT T L +L LL VPAAF Sbjct: 3822 AELDRWTEILDGPDPLIGSRPLDPRIDTVATLRSLRLTLPPGQAEPLLTSVPAAFHGRAG 3881 Query: 854 DILLVAFGLA---WTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALT 910 D+LL LA W T + +D+EGHGR +E+ VDLSRTVGWFT YPV L Sbjct: 3882 DVLLTGLALAVAHWRRKRGGRGTSVLLDLEGHGR-EEIFPGVDLSRTVGWFTAMYPVRLD 3940 Query: 911 VENLPWEQVVAGDAALGGIVKAVKEQLRSLPEGLTYGLLRYLNPEV--DLGG-SDPTIGF 967 W + A+ +K VKEQLR++P L YGLLR+L+P +L G P I F Sbjct: 3941 AGIGGW----TDERAVTQAIKQVKEQLRAVPNPLGYGLLRHLDPVAGPELAGLPQPQIVF 3996 Query: 968 NYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRAS 1027 NYLGR+ G+ W + MP+ HT+E+N T D +GP L A Sbjct: 3997 NYLGRVAVAEGD-----WNL----VPAGFGGHDPGMPVAHTLEINVTTHDRPDGPHLEAV 4047 Query: 1028 WTWAPSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRY 1087 W+W + L+ W EAL G+ AH G GG TPSD+ L Q +ID + + Sbjct: 4048 WSWPEGVLTGAEVRDLAGTWSEALEGLAAH---GRGGYTPSDLL-VDLDQNEIDRIQAAW 4103 Query: 1088 D 1088 + Sbjct: 4104 E 4104 Score = 533 bits (1373), Expect = e-148 Identities = 378/1056 (35%), Positives = 518/1056 (49%), Gaps = 109/1056 (10%) Query: 1051 LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFAR 1110 + G+ VR G G + S V P +QR++ L++ L P+ Sbjct: 2556 VGGVSGGVRPGVGRVVRSGVVPLSFSQRRLWFLNR---------LEPLSA---------- 2596 Query: 1111 GIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLT--ADPM 1168 VY + + + ++G +D LR A+ VV RH +L F E G Q + A+P Sbjct: 2597 -----VYNLPVVLRLSGGVDVGVLRGALGDVVGRHESLRTVFPEVGGVACQRILDPAEPA 2651 Query: 1169 IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHI 1228 + +L+ + E+ A DL P RA L ++H L HHI Sbjct: 2652 LEHVHLE--------EAELADALLASVGRGFDLAVEPPLRATLFTLGPDEHVIALVLHHI 2703 Query: 1229 VIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNWLXXXXXXXXXXX------ 1275 DGWS+ L +++ Y R+ + AP Y ++ W Sbjct: 2704 AGDGWSMAPLARDVITAYEARSRGRVASWAPLPVQYADYAVWQRELLGEESDPGSLVSRQ 2763 Query: 1276 ---WREVLDGFETPTLVAPPGVPGPR-GIESYR-------VSAETTRALGELARSQHTTI 1324 WR L G P +A P V PR + SYR + E R L LAR ++ ++ Sbjct: 2764 VGFWRAALAGL--PDEIALP-VDRPRPAVASYRGGSVPVSIGVEEVRRLRALAREENASL 2820 Query: 1325 NTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTV 1384 V+QAA LL R+ DV G+ V+GR + + +VG+ +NT+ +R D Sbjct: 2821 FMVVQAALAALLTRLGAGTDVPIGSVVAGRVDE--ALDDLVGMFVNTLVLRTDTGGDPGF 2878 Query: 1385 GDLLRQLQSHHNDTLEHEHLALNDIHHV------SGHEQLFDTLFLYESYPIDTSAFMGV 1438 +L+ +++ H+ L + + LF +++ P G+ Sbjct: 2879 RELVGRVREVDLAAYAHQDLPFERLVEIVSPARSMARHPLFQVALTFQNNPAAELELDGL 2938 Query: 1439 Q------ELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRL 1492 E V +F+ L + EL +EY T +FD E ++ RF RL Sbjct: 2939 SIRPEPVEAGVAKFDL-------LMSLTETAGELTGTLEYATDLFDPETAEGIVSRFLRL 2991 Query: 1493 LEAMIDDPARRLSSMDVVDDDER-TQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEA 1551 + A+ DP LS++D++D ER T L +WA P +I E F QV R P A Sbjct: 2992 VRAVTADPDVSLSAIDILDARERHTILRDWAGTG---SSPGVPSTIAEEFEAQVARSPHA 3048 Query: 1552 PAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAA 1611 AV G L+YGELD A LA +L G P + VAL+VPRS + +VA++AV+K G A Sbjct: 3049 VAVVGSGVELSYGELDARAGALARVLVGLGVGPERFVALVVPRSVELVVAVVAVVKAGGA 3108 Query: 1612 YLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLT 1671 Y+PIDP PA R+ ++ DA+PV AVT L V +D + P + Sbjct: 3109 YVPIDPGYPADRIAHIVRDARPVLAVTVPGSEGLLPA-GLPRVVLDGSVITAVPDAAVAG 3167 Query: 1672 PS-----PDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLV 1726 P AY+I+TSG+TG PKGV + HGNVT++L + VW+ +HS Sbjct: 3168 GEVGRLVPAHPAYVIFTSGSTGRPKGVVVPHGNVTRLLASTEGWFGFDETDVWTLFHSYA 3227 Query: 1727 FDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAV-------RM 1779 FD SVWE+WGALL+GGRLV+VP ++ SP + AL+ GV VL QTPSA R Sbjct: 3228 FDFSVWELWGALLYGGRLVVVPFEVSRSPGEFVALVAECGVTVLNQTPSAFYQFMRAERE 3287 Query: 1780 MSPEGLEGTALVVAGEACPTEVVDRW-----AVDRVMINAYGPTESTI---YAAISAPLS 1831 + L ++ GEA +D W V++N YG TE+T+ YAA+ + Sbjct: 3288 RAGVELSLRCVIFGGEALDPGRLDDWYGRHPETAPVLVNMYGITETTVHVTYAALDREAA 3347 Query: 1832 PGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVAC 1891 IG +P +VLDE+L PVPPGVVGELY+A LT RFVA Sbjct: 3348 VSGVGSVIGVGIPDLRVYVLDEFLCPVPPGVVGELYVAGAGVARGYVGRAGLTAERFVAD 3407 Query: 1892 PFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAV 1951 PFG G RMYR+GDL RW G+L++LGR D+QVKIRG+RIELGE++ L V A Sbjct: 3408 PFGVGGGRMYRSGDLARWDRAGRLEFLGRVDQQVKIRGFRIELGEVEGVLVGHPAVADAA 3467 Query: 1952 VIAREDRPGDKRLVGYITGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRR 2011 V+ REDRPGD+RLV Y+ GTA P A R+ LP YMVPAAVV LE LPLT NGKLDRR Sbjct: 3468 VVVREDRPGDRRLVAYVVGTATPDALRAWAREALPDYMVPAAVVVLEALPLTANGKLDRR 3527 Query: 2012 ALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVER 2047 ALP PE S+ R P T E L +FA VLGVER Sbjct: 3528 ALPVPEITSSG--REPSTPREALLCALFAEVLGVER 3561 Score = 444 bits (1142), Expect = e-122 Identities = 364/1084 (33%), Positives = 510/1084 (47%), Gaps = 112/1084 (10%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+ Q G+ A D ++ Q I I+G +D AV + R Sbjct: 11 LPLSAAQSGMWHAQRIAPE--DPIHIAQY-IEISGPVDPVLFASAVRLAAREVDAIHVRI 67 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALI 1212 VE G+ V+ +P A +LDL + + QL + L E AL+ Sbjct: 68 VEG-GQIVE--EREP--ACPFLDLGDERAALEWMRAQLASP-------LGEGSLLATALL 115 Query: 1213 RTSGNQHRFVLTFHHIVIDGWSLPILLQ---EIFAGYFGHRLPAAAPYRNFVNWLXXXXX 1269 R + +++ + L HH+++DG+S P++ Q E++ R P + L Sbjct: 116 RVADDRYLWYLRCHHVIMDGYSGPMIAQRLAEVYTALAEGRDPDPGGLGSLATLLEEDAA 175 Query: 1270 XXXXXXWR--------EVLDGFETPTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQ 1320 + ++ D P L + V R S + AL E A S Sbjct: 176 YRASDRFEADRRHWLGKLADLPAVPALSSGTAVATSRFHRWSAMLGERDAAALTEGALSH 235 Query: 1321 HTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSA 1380 T ++ ++ AA + R+TG ++V G AV+ R A G++ N +P+R V Sbjct: 236 GTAVSGLMIAAVAAFVGRLTGAQEVVLGLAVTARTTPTA--RRTPGMVSNVLPLRLAVRP 293 Query: 1381 DTTVGDLLRQLQSHHNDTLEHEHLALNDIHH-VSGHEQLFDTLFLYESYPIDTSAFMGVQ 1439 TT G+L+ Q+ L H+ D+ V G +LF + + D F G Sbjct: 294 QTTFGELVGQVTREVGRLLVHQRYRYEDLRREVRG--RLFGPVVNIMRFDYDLK-FAGH- 349 Query: 1440 ELAVTEFNNREYNHYPLSVMALPGHE-LGLRVEYD--TSVFDVSEIETLIDRFQRLLEAM 1496 A T LS+ G + G+R+++D ++ +E+ DRF R L + Sbjct: 350 --AATAHPLSTGPIEDLSINLYDGSDGRGVRIDFDGHPELYGEAELADHHDRFLRCLAQI 407 Query: 1497 ID-DPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPE-----VFARQVERDPE 1550 P R+ ++D++D+ ER L +W +P+ +P+ +F QV R PE Sbjct: 408 AQASPDLRVGAIDLLDEAERALLGDWGG---------APREVPDGTAVTLFEEQVRRRPE 458 Query: 1551 APAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGA 1610 A AV + Y EL+ AN+LA+ L GA P + V L VPRS D +VA LA+LK+GA Sbjct: 459 AVAVVAGDTEVTYAELNVRANRLAHHLIARGAGPDRYVGLSVPRSLDMVVAFLAILKSGA 518 Query: 1611 AYLPIDPSVPAARLEFMLGD-AKPV----------------------------------A 1635 AYLP+DP P RL ML D A P+ A Sbjct: 519 AYLPLDPDYPRDRLAVMLADAAPPIVVTCAAAGLLPPPGADTVDARTGESLAGAGAGAGA 578 Query: 1636 AVTTGDLRSRFDG--------------FDLQVVEVDDPAVEIYPSTTLLTPS-PDDIAYM 1680 GD DG +VV +D + P + +T P AY+ Sbjct: 579 GAGAGDGGGSGDGGGAGRAGTRIEDGLSGAEVVMMDTWTGDGLPGSDPVTALLPGHPAYV 638 Query: 1681 IYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLH 1740 ++TSG+TG+PKGV +TH + T + Q+ S+ FD +V E A Sbjct: 639 VFTSGSTGLPKGVLVTHAGLPGYARTEIDRYAVTEDSRVLQFASIGFDGAVLEWLMAFSS 698 Query: 1741 GGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGT-ALVVAGEACPT 1799 G LV+ P + G + L L V + TP+A+ + L L+V GEAC Sbjct: 699 GAALVLAPAGVYGG-EPLGRFLAETRVTHAFITPAALATIPERPLPDLRTLLVGGEACRP 757 Query: 1800 EVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVP 1859 E+V RW+ R MIN YGPTE+T+ A S PL+ D PIG PV VLD LRPVP Sbjct: 758 ELVRRWSAGRRMINVYGPTETTVVVATSDPLTSPDDT-PIGRPVYDTRLHVLDPGLRPVP 816 Query: 1860 PGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLG 1919 PG GELY+A LT RFVA P G G RMYRTGDLVRWG DGQLQYL Sbjct: 817 PGTAGELYVAGPSVARGYLNRPGLTAERFVADPTGA-GGRMYRTGDLVRWGADGQLQYLD 875 Query: 1920 RADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARS 1979 RAD QVK+RG+RIELGEI++ L+ GV QA V+AR+D+PGD+RLV Y+TGTAD R Sbjct: 876 RADRQVKVRGFRIELGEIESVLAGHPGVGQAAVLARDDQPGDRRLVAYVTGTADADELRR 935 Query: 1980 ELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIF 2039 LP YMVPAA+V L+ +PLT NGKLDRRALPAPE +++ R P T+ E+ L +F Sbjct: 936 HARRALPDYMVPAAIVVLDAMPLTANGKLDRRALPAPERETSG--REPATDRERLLCALF 993 Query: 2040 AHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEH 2099 A VLGVER A+R+ A A L+ + +F+ + L+L V H Sbjct: 994 AEVLGVERVGADDGFFDLGGDSILAIRLVARAREA-GLGLTPKHVFQHRSPEALAL-VAH 1051 Query: 2100 DAGE 2103 +A E Sbjct: 1052 EAVE 1055 Score = 417 bits (1073), Expect = e-114 Identities = 322/930 (34%), Positives = 444/930 (47%), Gaps = 115/930 (12%) Query: 41 VTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPR 100 VT+ LF EQV R PDA ALVS +Y + +NRLA +LAEH A P VA ++PR Sbjct: 1966 VTLAGLFEEQVARTPDATALVSEGVELSYAAFNARANRLARLLAEHEAGPERVVALMLPR 2025 Query: 101 SGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVI 160 S + ++++ +V+K GAAYLP+DP P RI M+ DA+PV +D LA Sbjct: 2026 SPDLLVAMYAVVKAGAAYLPIDPGLPAGRIASMLDDARPVLV---------IDHDWLAGA 2076 Query: 161 DMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSG 220 D++ + + + P PD+ AY+ YTSG+TG PK V V+H ++ + + Sbjct: 2077 DVSGCSAE----NLEVRPAPDNPAYVIYTSGSTGRPKGVVVSHRSIVNRLLWAQSRYGLR 2132 Query: 221 PGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTP 280 Q FDVSVWE + L G LV+ P L L+ E+V+ + P Sbjct: 2133 ADDRVLQKTPAGFDVSVWEFFWPLQTGAALVIARPGGHRDPAYLAGLIDAERVTTVHFVP 2192 Query: 281 SAAGML-----SPEGLESTTLIVAGEACPTELVDRWAP--GRVMINAYGPTEATIYAAMS 333 S + P +I +GEA P E+ D+ G + N YGPTEA + Sbjct: 2193 SMLAVFLAASDGPAPASLRRVICSGEALPPEVADQAVARLGVPVHNLYGPTEAAVDVTYW 2252 Query: 334 EPL-XXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTAS 392 E ++VLD WLRP P GV GELY+AG +A GY+GR LTA Sbjct: 2253 EHRPDPDGGSVPIGRPVWNTRVYVLDPWLRPVPVGVAGELYLAGVQLARGYLGRGGLTAE 2312 Query: 393 RFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDG 452 RFVACPFG GERMYRTGD+VRW +DG L+Y+GRAD QVK+RG+RIELGE++A LA+ Sbjct: 2313 RFVACPFGGPGERMYRTGDVVRWRADGGLDYVGRADFQVKVRGFRIELGEVEAVLARHGS 2372 Query: 453 VDQAVVIAREDRPGDKRLVGYIT---------------------------------GTAD 479 V V+ REDRPGD+RLV Y+ D Sbjct: 2373 VSGVAVVVREDRPGDRRLVAYVVPAPAGPVEGDMLAVPARRAGGEAVAAPVGRVVPAEVD 2432 Query: 480 PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAE 539 A+LR + E LP YMVP+ VVVLD +P+T NGKLDR ALP PE + R P + E Sbjct: 2433 AAELRRWVGEVLPEYMVPSVVVVLDVLPVTRNGKLDRAALPVPEV--SVGSGRGPRSVVE 2490 Query: 540 QILADVYAQVLGVER-VGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXX 597 ++L V+A+VLG + VGVDDSFFDLGGDS+L M++V+R R+ ++ R +F + Sbjct: 2491 EVLCGVFAEVLGFDGVVGVDDSFFDLGGDSLLVMRLVSRVRSVLSVELPVRVVF--EASS 2548 Query: 598 XXXXXXXXXXESHVVDEGVGPVVATPI---------MRWLREVDGPTGQFNQTVITQAPA 648 S V GVG VV + + + +L ++ + +N V+ + Sbjct: 2549 VAALAVWVGGVSGGVRPGVGRVVRSGVVPLSFSQRRLWFLNRLEPLSAVYNLPVVLRLSG 2608 Query: 649 GVTEDDVVVILQALLD---RHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVD-- 703 GV DV V+ AL D RH +LR + PE G V + L + Sbjct: 2609 GV---DVGVLRGALGDVVGRHESLR--------------TVFPEVGGVACQRILDPAEPA 2651 Query: 704 ---------ALTDDVLVEARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWR 751 L D +L D A + A + + L++HH+A DG S Sbjct: 2652 LEHVHLEEAELADALLASVGRGFDLAVEPPLRATLFTLGPDEHVIALVLHHIAGDGWSMA 2711 Query: 752 ILLEDLNIAWAQHCTGQSIE---LPAGGTSFARWS-ALLAEHAKTDT-VRDLADAWR-AV 805 L D+ A+ G+ LP +A W LL E + + V WR A+ Sbjct: 2712 PLARDVITAYEARSRGRVASWAPLPVQYADYAVWQRELLGEESDPGSLVSRQVGFWRAAL 2771 Query: 806 TSVPQ--ALPPVQP-DTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGL 862 +P ALP +P G + S+ VE R+L + A + ++ A Sbjct: 2772 AGLPDEIALPVDRPRPAVASYRGGSVPVSIGVEEVRRLRA-LAREENASLFMVVQAALAA 2830 Query: 863 AWTEFLNRSDTPIGVDVEGHGRYDELASDV 892 T +D PIG V GR DE D+ Sbjct: 2831 LLTRLGAGTDVPIGSVVA--GRVDEALDDL 2858 >tr|B1VL65|B1VL65_STRGG Tax_Id=455632 SubName: Full=Putative NRPS;[Streptomyces griseus subsp. griseus] Length = 4935 Score = 1347 bits (3486), Expect = 0.0 Identities = 868/2141 (40%), Positives = 1157/2141 (54%), Gaps = 124/2141 (5%) Query: 36 PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA 95 P T ++ F P A ALV+ D+ TY EL ++RLAH L E GA P VA Sbjct: 1501 PACTEGSVAERFDAWAAARPRATALVTEDQELTYAELAARTDRLAHWLREQGAGPERFVA 1560 Query: 96 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQY 155 +PR+ + ++++L+VLK+GAAYLPVDPA P RI +++ DA+P+ LT ++ + Sbjct: 1561 VRLPRTVDLVVALLAVLKSGAAYLPVDPALPADRIAYLLRDAQPLLVLTEEEMA----RA 1616 Query: 156 DLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHA 215 D A A PA R P D AY+ YTSG+TG PK V V + L+ +L Sbjct: 1617 DRAGAPTAAPAPVRHP---------DHPAYVIYTSGSTGRPKGVVVPGGGMVNLLDSLVR 1667 Query: 216 DLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSV 275 L P + ++ FD++V EI+ L GG LV+ P++L LL +V Sbjct: 1668 RLGLTPDDRTAAVSTVGFDIAVMEIFLPLTSGGTLVLAGSDAVKDPEELGALLTRTGTTV 1727 Query: 276 LCQTPSAAGMLS---PEGLESTTLIVAGEACPTELVDRW-APGRVMINAYGPTEATIYAA 331 L PS +L P+ L + GEA +L R A G + N YGPTE T+ A Sbjct: 1728 LAAAPSLWHVLEETVPQALRGLRKMTGGEALAPDLARRLVALGGPVFNLYGPTEITVCAT 1787 Query: 332 MSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTA 391 +E + VLD LRP P GV GELY+AG GV GY GRP LTA Sbjct: 1788 GAE--MDGVAPVTIGGPIGGTRVHVLDAALRPVPPGVPGELYIAGAGVTRGYHGRPGLTA 1845 Query: 392 SRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLD 451 RFV P+G G RMYR+GDLVRWG +G+L+YLGR D QVK+RG+RIELGEI+ L Sbjct: 1846 ERFVPDPYGPAGTRMYRSGDLVRWGDEGRLDYLGRTDFQVKLRGFRIELGEIEEVLGGHG 1905 Query: 452 GVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIP 507 V +AVV E RPGD+RLV ++ T D A LR A +LPAYMVP A VVLD +P Sbjct: 1906 DVGRAVVGVHEFRPGDRRLVAHVMPAEGRTVDAAVLREHAAAALPAYMVPAAFVVLDELP 1965 Query: 508 LTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGD 567 L N K+DR+ALPAPE R P E L ++A+VLG+ERV V +SFF +GGD Sbjct: 1966 LNANAKVDRKALPAPE-TDGGEPSREPRNATEATLCAIFAEVLGLERVDVAESFFAVGGD 2024 Query: 568 SILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVV-----DEGVGPVVAT 622 SI S+Q+V RAR G++ PRD+F +T V + VG V T Sbjct: 2025 SISSIQLVGRARQEGLRFSPRDVFEHRTPQALAAAVLAEAAGPVAPDVSRSDAVGDVPLT 2084 Query: 623 PIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDE 682 PI+ W+RE G QFNQT+ PAG V +QA+LD H LR+R++ ED Sbjct: 2085 PIVHWVRERGGAIDQFNQTMSLPVPAGTEPAAVASAVQAVLDHHDALRMRLDRLGEDFG- 2143 Query: 683 WSLLVPEAGAVGARECLRTVDA-------LTD--------DVLVEARNRLDPAAGAMVSA 727 WSL + G V A +C+ VDA LT+ + + A+ RLDP AGAMV Sbjct: 2144 WSLEIDPPGTVRAEDCVHRVDAAALIASGLTEAELDLRAGEEIAAAQARLDPGAGAMVRC 2203 Query: 728 VW----VRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWS 783 VW + +L ++ HHL VDGVSWRILL DL A G++ L GTSF WS Sbjct: 2204 VWFDTGAKAPGRLTVIAHHLVVDGVSWRILLPDLQAALEALAAGRTAVLEPVGTSFRDWS 2263 Query: 784 ALLAE-HAKTDTVRDLADAWRAV---TSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQ 839 L + A D +R+L WR + + P P+ DT+ TA QLS L + T Sbjct: 2264 RRLTDLAAAPDRMREL-PLWRDILDGSDTPLTDRPLDAKRDTFGTAAQLSVQLPAKLTAP 2322 Query: 840 LLGEVPAAFRAGVQDILLVAFGLA---WTEFLNRSDTP-IGVDVEGHGRYDELASDVDLS 895 LLG +PA F G+ D+LL A LA W R D P + +D+EGHGR +E+A VDLS Sbjct: 2323 LLGRIPALFNTGINDVLLTALALAVIDWRGRTGRGDDPEVLIDLEGHGR-EEIADGVDLS 2381 Query: 896 RTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNP 954 RTVGWFT+ YP+ LT P E+V +G A+G VK +KEQ R LP+ G+ +GLLR+LNP Sbjct: 2382 RTVGWFTSLYPLRLTPGETPGEEVWSGGPAVGRAVKRIKEQRRVLPDNGIGFGLLRHLNP 2441 Query: 955 EVD--LGG-SDPTIGFNYLGRL-----GAGAG---ELSEELWRIDQXXXXXXXXXXXVPM 1003 + LG + P IGFNYLGRL GAG G E++ L + + M Sbjct: 2442 QTAQVLGRFAQPQIGFNYLGRLGEADDGAGTGREPEVNRGLSNVAE-----------AAM 2490 Query: 1004 PLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVR--GG 1061 L H ++L A + +GP L A W WA F ++ L+R WF AL + H G Sbjct: 2491 ALPHALDLTATAVTYPDGPRLVAHWIWAGELFSDDDMRDLARTWFRALEALVLHAERPEG 2550 Query: 1062 GGGLTPSDVAPARLTQRQIDEL-SQRYDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQ 1120 GGL+PSD+ L Q +ID L S DV DVLPL+P+Q+GLLFH+ + G D+Y Sbjct: 2551 AGGLSPSDLTLVDLGQEEIDRLASAGDDVVDVLPLSPLQEGLLFHALYDER-GADIYTTL 2609 Query: 1121 LDITITGVLDQHRLRDAVHTVVARHPNLAARF-VEQFGEPVQVLTADPMIAWRYLDLRG- 1178 L + G LD LRDA ++ RH NL A F G+ +QV+ + WR +DL G Sbjct: 2610 LAFELRGELDASALRDAAGALLRRHDNLRAAFRPGAAGQSLQVIPRTVELPWRQVDLSGY 2669 Query: 1179 DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPIL 1238 D+ E+++L A + D + P R L+RT HR +L HHI+ DGWS P+L Sbjct: 2670 DEERRTRELDRLTAEALAERFDPRQAPLLRFTLVRTGAKAHRLLLANHHILFDGWSGPVL 2729 Query: 1239 LQEIF----AGYFGHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG- 1293 E+F G LPA PY+++++WL WRE LDG + PTLVAP Sbjct: 2730 SAELFELYRTGGDDAALPAVTPYKDYLSWLAGQDRAAAESAWREALDGVDEPTLVAPADP 2789 Query: 1294 VPGPRGIESYR--VSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAV 1351 P S+R +SA T AL AR T NTV+QAAW LL +TG+ DV FG V Sbjct: 2790 ARAPLRPRSHRLELSAAETAALTGRARRSGVTKNTVVQAAWGLLLCGLTGREDVTFGETV 2849 Query: 1352 SGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHH 1411 +GRPA+L G E+MVGL INT+P+R + T+ D++ +L+ + L H++L L DI Sbjct: 2850 NGRPAELPGVETMVGLFINTLPVRVRAGRGDTLLDVVHRLRDQQLELLPHKYLGLTDIQR 2909 Query: 1412 VSGHEQLFDTLFLYESYPIDTSAFMGVQE-LAVTEFNNREYNHYPLSVMAL-PGHELGLR 1469 ++G LFDT + SYP+D+ E + + + ++ HYPL++ A G L L Sbjct: 2910 ITGTGALFDTSTEFSSYPVDSETLERTAEGIGIVDAQIQDGTHYPLALGASDDGRNLTLT 2969 Query: 1470 VEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDD-DERTQLDEWANRAVLT 1528 ++Y ++D E L R + +LEA DP R S+D++ + RT L EW + A Sbjct: 2970 IDYRPDLYDDGTAEALGARLRAILEAFAADPGCRADSLDLLTEAGRRTLLVEWNDTAAEV 3029 Query: 1529 QPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSV 1588 ++PE+F Q R P+APAV F L+Y +LD +++LA LLA G P V Sbjct: 3030 ----PAGAVPELFRAQARRTPDAPAVVFGDTRLDYRDLDARSDRLAGLLAGLGVGPETPV 3085 Query: 1589 ALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDG 1648 +++ RSA+ V +LAVLK G AY+P+ + PA RL +L D VT G Sbjct: 3086 GVLMERSAELPVVLLAVLKAGGAYVPLRDTDPAPRLRRLLADTGARVVVTDGASAPLAGE 3145 Query: 1649 FDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLP 1708 + V++ D + P T+L PD +AY++YTSG+TG+PKGV IT ++ + Sbjct: 3146 LGVTVLDARDDSPAQAPRVTVL---PDQLAYVMYTSGSTGLPKGVEITQRDIVGL--AFD 3200 Query: 1709 AELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVN 1768 +G FD S +E W LL GG +V+ P A S L LL + V Sbjct: 3201 RRWESGAHRRVLMHSPTAFDASTYESWVPLLRGGAVVVAPPG-ALSVAALEQLLATHEVT 3259 Query: 1769 VLYQTPSAVRMM---SPEGLEGTALV-VAGEACPTEVVDRWAV---DRVMINAYGPTEST 1821 L+ T R++ SP L G V G+ P E V R V+ + YGPTE+T Sbjct: 3260 GLWLTAGLFRLVAEESPGALSGLREVWTGGDVVPAEAVRRVLAACPGIVVTDGYGPTETT 3319 Query: 1822 IYAAISAPLSPGSDV---VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXX 1878 + A+S PL+ V VPIG P+ +VLD LRPVP GV GELY+A Sbjct: 3320 TF-ALSHPLTAAEPVPARVPIGRPLDNTRVYVLDGSLRPVPAGVAGELYIAGAGLARGYT 3378 Query: 1879 XXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQ 1938 T RFVA PFG PGARMYRTGDLVRW DG +++ GRAD+Q+K+RG+RIE GEI+ Sbjct: 3379 RRPAATAGRFVANPFGPPGARMYRTGDLVRWTADGVVEFAGRADDQIKLRGFRIEPGEIE 3438 Query: 1939 AALSDVDGVDQAVVIAREDRPGDKRLVGYIT-----GTADPAAARSELTNRLPAYMVPAA 1993 L+ V QA V+ REDRPGD+RLVGY G A A + L+ LP YMVP+A Sbjct: 3439 DRLARHPAVAQAAVLVREDRPGDRRLVGYAVLADPDGPATTADLTAYLSGELPDYMVPSA 3498 Query: 1994 VVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXX 2053 +V + LPLT NGK+DRRALPAPEY AQ RAP E EKTL ++A +LGV Sbjct: 3499 LVAVAALPLTANGKIDRRALPAPEYGGAQERRAPRDEREKTLCALYAEILGVPEVGIDDS 3558 Query: 2054 XXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 A R+ + +A A++ VR +FEAPTVA L+ Sbjct: 3559 FFDLGGHSLLATRLVNRIRSAFGAEVPVRLVFEAPTVAALA 3599 Score = 999 bits (2583), Expect = 0.0 Identities = 644/1633 (39%), Positives = 874/1633 (53%), Gaps = 92/1633 (5%) Query: 469 RLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAA 528 RL+ + AD +LR E A A +VL +G DR A PA R AA Sbjct: 417 RLLAVLAEFADRPELRVGELELFDA--ADRARLVLPP-----SGPADRAARPAGTDRPAA 469 Query: 529 NDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPR 588 D P+ E +L + A+VLGVE V V D+FF+ GGDSI S+Q+ RAR I R Sbjct: 470 ADGE-PANEREALLCRLVAEVLGVESVSVHDNFFERGGDSISSIQLAHRARKENIALTLR 528 Query: 589 DIFVEQTXXXXXXXXXXXXESH--VVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQA 646 +IF +T D+GVGPV TP+M W + G FNQT+ Sbjct: 529 EIFEHRTVSRLAALAGAAPRPAPAAADDGVGPVPLTPVMHWQQSQGGRIDAFNQTLTVPV 588 Query: 647 PAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR------ 700 PAG+T+D + LQALLD H LR+R+ + EW+L V GAV A +C+R Sbjct: 589 PAGLTQDRLHTALQALLDHHDALRMRLG--RAPGQEWTLEVMARGAVRAEDCVRRYATGS 646 Query: 701 ---TVDALTDDVLVEARNRLDPAAGAMVSAVW----VRETSQLVLMIHHLAVDGVSWRIL 753 + ++ ++ A RL PA G MV AVW L L+IHHLAVDGVSWRIL Sbjct: 647 GDPAAERTHEEQVLAAVERLAPAEGRMVQAVWHDAGPDAEGLLALVIHHLAVDGVSWRIL 706 Query: 754 LEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQ--- 810 L DL A A +G I L GTS RWS LAE A T+ D WR V + P Sbjct: 707 LPDLEAALAALGSGDPIVLDPVGTSLRRWSRGLAEEALTERRVAELDLWRTVLATPDPHL 766 Query: 811 ALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA---WTEF 867 A P D A QL+ +L TT +LG VPA F AG + +L A LA W Sbjct: 767 ADRRTDPARDVVGAARQLTVTLPATTTAAVLGAVPALFHAGADEAMLTALALAVARWRRE 826 Query: 868 LNRSD-TPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALT--VENLPWEQVVAGDA 924 R + + + V +EGHGR +E+ VDLSRTVGWFT+ YPVA+ E+ +G Sbjct: 827 RGRGEGSAVLVGLEGHGR-EEILDGVDLSRTVGWFTSLYPVAVDPGAGADADEETWSGGP 885 Query: 925 ALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEVD---LGGSDPTIGFNYLGRLGAGAGEL 980 A+G KAVKEQLR++P+ G+ YGLLR+LNP+ G ++P IGFNYLGRLG + Sbjct: 886 AIGTAFKAVKEQLRAIPDKGMGYGLLRHLNPDTGPELAGFAEPQIGFNYLGRLGTADADA 945 Query: 981 SEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQA 1040 + R+ MPL +T+ELNA +D +G L ASWTW+ E + Sbjct: 946 DPDAVRVRDLTGAGD-----ASMPLPYTLELNAAAVDHTDGQRLTASWTWSGELLGEAEV 1000 Query: 1041 TRLSRLWFEALAGICAHV-RGGGGGLTPSDVAPARLTQRQIDELSQRYD-VTDVLPLTPV 1098 TR++RLWF+AL + AH R GGLTPSD+ +TQ +ID L + DVLPL+P+ Sbjct: 1001 TRIARLWFDALTALAAHAERPDAGGLTPSDLPLVTVTQAEIDRLETTPGAIVDVLPLSPL 1060 Query: 1099 QQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVE-QFG 1157 QQGL FH + DVY +Q + + G ++ LR+A ++ RH NL A FV G Sbjct: 1061 QQGLHFHGLYDAS-ETDVYTIQSVLELRGPVEPEALREAARALLRRHDNLRAFFVTGAAG 1119 Query: 1158 EPVQVLTADPMIAWRYLDLRG---DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRT 1214 P+QV+ A W DL G +D T E+E+L A++R DL P R L+R Sbjct: 1120 GPLQVIPAQAEPPWASHDLSGLADEDRTA--ELERLLASDRGTRFDLETSPPLRCTLVRL 1177 Query: 1215 SGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL---PA---AAPYRNFVNWLXXXX 1268 HRFVLT HHI +DGWS+P+L++++F Y H+ PA AAPY+ ++ WL Sbjct: 1178 GERDHRFVLTVHHIAVDGWSMPLLVRDLFDLYGSHQRGEEPAPSPAAPYKRYLTWLAAQD 1237 Query: 1269 XXXXXXXWREVLDGFETPT-LVAPPGVPGPRGIESYR--VSAETTRALGELARSQHTTIN 1325 WR L G + T LV G G E + E + L +AR T+N Sbjct: 1238 RGVSEDAWRTALAGLDEVTHLVTDAGAAGSAAPERLGTDIPEELSAGLTAVAREHGLTVN 1297 Query: 1326 TVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVG 1385 T++Q AW +L +TG+ DV FG VSGRP +L G E M+GL INT+P+R + ++ Sbjct: 1298 TLVQGAWGLVLSALTGRDDVVFGATVSGRPPELPGVEDMIGLFINTLPVRMDIDHGVSLA 1357 Query: 1386 DLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFM-GVQELAVT 1444 L ++LQ + + H++L L D+ ++G +LFDTL ++E+YP+++ QEL V Sbjct: 1358 GLFQRLQERQSGLMAHQYLGLADVQRLAGSGELFDTLVVFENYPVESEPLRESAQELGVV 1417 Query: 1445 EFNNREYNHYPLSVMALP-GHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARR 1503 + + HYP++++A G L + Y + D + +E + +RF +L A D P R Sbjct: 1418 DAEVHDAVHYPIALLAAQRGDRLTVEWSYRPDLLDRARVEAVAERFVAVLRAFADGPGRP 1477 Query: 1504 LSSMDVVDDDE-RTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLN 1562 +++D++ E R L EW++ A P + S+ E F P A A+ E + L Sbjct: 1478 AAALDLLAPAERRLVLGEWSDGA----PACTEGSVAERFDAWAAARPRATALVTEDQELT 1533 Query: 1563 YGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAA 1622 Y EL ++LA+ L GA P + VA+ +PR+ D +VA+LAVLK+GAAYLP+DP++PA Sbjct: 1534 YAELAARTDRLAHWLREQGAGPERFVAVRLPRTVDLVVALLAVLKSGAAYLPVDPALPAD 1593 Query: 1623 RLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIY 1682 R+ ++L DA+P+ +T ++ +R D P P PD AY+IY Sbjct: 1594 RIAYLLRDAQPLLVLTEEEM-ARAD-------RAGAPTAAPAP-----VRHPDHPAYVIY 1640 Query: 1683 TSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGG 1742 TSG+TG PKGV + G + +LD+L L P + ++ FD++V EI+ L GG Sbjct: 1641 TSGSTGRPKGVVVPGGGMVNLLDSLVRRLGLTPDDRTAAVSTVGFDIAVMEIFLPLTSGG 1700 Query: 1743 RLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS---PEGLEGTALVVAGEACPT 1799 LV+ P++L ALL G VL PS ++ P+ L G + GEA Sbjct: 1701 TLVLAGSDAVKDPEELGALLTRTGTTVLAAAPSLWHVLEETVPQALRGLRKMTGGEALAP 1760 Query: 1800 EVVDRW-AVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPV 1858 ++ R A+ + N YGPTE T+ A + G V IG P+ VLD LRPV Sbjct: 1761 DLARRLVALGGPVFNLYGPTEITVCA--TGAEMDGVAPVTIGGPIGGTRVHVLDAALRPV 1818 Query: 1859 PPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYL 1918 PPGV GELY+A LT RFV P+G G RMYR+GDLVRWGD+G+L YL Sbjct: 1819 PPGVPGELYIAGAGVTRGYHGRPGLTAERFVPDPYGPAGTRMYRSGDLVRWGDEGRLDYL 1878 Query: 1919 GRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADP 1974 GR D QVK+RG+RIELGEI+ L V +AVV E RPGD+RLV ++ T D Sbjct: 1879 GRTDFQVKLRGFRIELGEIEEVLGGHGDVGRAVVGVHEFRPGDRRLVAHVMPAEGRTVDA 1938 Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKT 2034 A R LPAYMVPAA V L+ LPL N K+DR+ALPAPE + R P TE T Sbjct: 1939 AVLREHAAAALPAYMVPAAFVVLDELPLNANAKVDRKALPAPETDGGEPSREPRNATEAT 1998 Query: 2035 LAGIFAHVLGVER 2047 L IFA VLG+ER Sbjct: 1999 LCAIFAEVLGLER 2011 Score = 449 bits (1155), Expect = e-123 Identities = 362/1136 (31%), Positives = 527/1136 (46%), Gaps = 110/1136 (9%) Query: 1033 SAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDV 1092 SAF E RL FEA V G LT ++ A RL + Sbjct: 3578 SAFGAEVPVRLV---FEAPT-----VAALAGRLTGAEAAKQRLVPGERPA---------A 3620 Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ Q+ L F + Y +QL + + G +D + AV VV RH +L F Sbjct: 3621 IPLSHAQRRLWFIDSVEEDATGS-YTIQLAVRLLGEVDPGAMEAAVADVVGRHESLRTVF 3679 Query: 1153 VEQFGEPVQ-VLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAAL 1211 + G P Q +LT D ++ +D +E ++V DL RA L Sbjct: 3680 PVEDGAPRQRILTPDEYTVPLPVEAVAED-----GLEAALKESAASVFDLAADVPLRARL 3734 Query: 1212 IRTSGNQHRFVLTFHHIVIDGWSLPILLQEI---FAGYFGHRLPAAAP----YRNFVNWL 1264 +R + +H L HHI DG SL L +++ +A P AP Y ++ W Sbjct: 3735 LRLAPREHVLDLVLHHIAADGSSLAPLARDLGLAYAARLERTEPEFAPLPVQYADYALWQ 3794 Query: 1265 XXXXXXXXXXX---------WREVLDGFETPTLV-------APPGVPGPRGIESYRVSAE 1308 WR L G + A G PG G R Sbjct: 3795 RRTLGDESDPESPYGRQLAHWRTALAGLPEELDLPVDRPRSAEAGSPG--GQVELRFPDA 3852 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLL 1368 + LA ++ VL AA L R+ G D+ GT V+GR + + +VG Sbjct: 3853 VVEGVHRLADEGGASLFMVLHAAVAATLHRVGGGTDIPVGTVVAGRGDE--ALDELVGFF 3910 Query: 1369 INTVPIRAKVSADTTVGDLLRQLQ-------SHHNDTLEHEHLALNDIHHVSGHEQLFDT 1421 +NT+ +R +S +LLR+++ SH + E LN + G LF Sbjct: 3911 VNTLVLRTDLSGAPDFRELLRRVRNTDLTAFSHQDVPFERLVEELNPARSL-GRNPLFQV 3969 Query: 1422 LFLYESY-------------PIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGL 1468 E+ P T+A + +L+ T F + P LG Sbjct: 3970 AVSLENNEEADLELPGLTLAPQPTTADLAKFDLSFT-FGEIRPDSGPAG--------LGG 4020 Query: 1469 RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLT 1528 +++Y+ ++FD S E L DR RLL A++ DP ++ +D++ ERT L E N Sbjct: 4021 QLDYNAALFDHSTAEALADRLVRLLAAVVADPGLPVADVDLLSPRERTVLQE-RNDTARA 4079 Query: 1529 QPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSV 1588 +P + I FA +V +P+APAV+ G ++ Y ELD AN+LA+ L G APG V Sbjct: 4080 RPAGT---IVSRFAERVAAEPDAPAVSDRGVTIGYAELDARANRLAHRLIAAGVAPGDRV 4136 Query: 1589 ALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDG 1648 A++ RSAD +V+ LAVLK GAAY+P+D P RL ++ + +T L Sbjct: 4137 AVLQERSADLVVSTLAVLKAGAAYVPLDARYPLPRLGLIVEETGSRVLLTDRALSKVAVD 4196 Query: 1649 FDLQVVEVDDP-----AVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQV 1703 +V+ VD + + P + + P D++AY++YTSG+TG PKG+ +TH NV Sbjct: 4197 GPAEVIVVDGGREAARSTDPDPGSPDIAPHQDELAYVMYTSGSTGKPKGIGVTHANVV-- 4254 Query: 1704 LDTLPAELPAGPGAVWSQWHSL-VFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALL 1762 A+ G +HS FD S +EIW LL G LV+ P + L L Sbjct: 4255 --AFAADERWRSGHEKVLFHSPHAFDASTYEIWATLLGGAHLVVAPPGQLDA-SGLRRLT 4311 Query: 1763 VSEGVNVLYQTPSAVRMMSPEGLEGTA----LVVAGEACPTEVVDRW---AVDRVMINAY 1815 EG+ ++ T + +++ E A + GE R D +++ Y Sbjct: 4312 EEEGLTAVFMTTALFNLIAEEDPGAFAGLREIWTGGEQVSPAAFQRVLAACADTAVVHVY 4371 Query: 1816 GPTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXX 1872 GPTE+T+YA + AP++ VP+G P+ +VLD+ LRPVP GV GELYLA Sbjct: 4372 GPTETTVYALCVPLRAPVA-ALRTVPVGRPMDNTRAYVLDDRLRPVPFGVAGELYLAGAG 4430 Query: 1873 XXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRI 1932 +T RF+A PFG G RMYRTGD+VR +G ++++GRAD QVKIRG RI Sbjct: 4431 TARGYPGLPGMTAERFLADPFGAGGERMYRTGDVVRQDAEGLIEFVGRADHQVKIRGLRI 4490 Query: 1933 ELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGT--ADPAAARSELTNRLPAYMV 1990 ELGEI++ L D V + +V RED PGDK+LV Y+ AD A R ++ RLP YMV Sbjct: 4491 ELGEIESVLQDQPQVSRTLVTVREDAPGDKKLVAYLVPVPGADTAGLREQVARRLPDYMV 4550 Query: 1991 PAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXX 2050 P+A V L LP+ NGK+DR+ALPAP++ A R P E+ L ++A L ++R Sbjct: 4551 PSAFVYLPDLPVNANGKVDRKALPAPDFGPAAGGRGPRDPREELLCRLWAEALKLDRVGI 4610 Query: 2051 XXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTD 2106 ++++T+ V + +LS R +F+APTVA L + V G+R D Sbjct: 4611 DDNFFELGGDSIVSLQLTSRVRSVFGVELSNRAVFQAPTVASL-MEVMGAGGQRDD 4665 Score = 409 bits (1051), Expect = e-111 Identities = 319/938 (34%), Positives = 447/938 (47%), Gaps = 59/938 (6%) Query: 19 DEHDQIEVWGNRAVLTDPGPTPVTIPA-----LFAEQVVRAPDAVALVSGDRSWTYRELD 73 D D + G R +L + T +PA LF Q R PDA A+V GD YR+LD Sbjct: 3005 DSLDLLTEAGRRTLLVEWNDTAAEVPAGAVPELFRAQARRTPDAPAVVFGDTRLDYRDLD 3064 Query: 74 EASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFM 133 S+RLA +LA G P V L+ RS E + +L+VLK G AY+P+ P R+ + Sbjct: 3065 ARSDRLAGLLAGLGVGPETPVGVLMERSAELPVVLLAVLKAGGAYVPLRDTDPAPRLRRL 3124 Query: 134 MSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTT 193 ++D +T + + V+D D + + P + PD LAY+ YTSG+T Sbjct: 3125 LADTGARVVVTDGASAPLAGELGVTVLDARDDSPAQAPRVTVL---PDQLAYVMYTSGST 3181 Query: 194 GVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVV 253 G+PK V +T ++ L A SG + FD S +E W LL GG +VV Sbjct: 3182 GLPKGVEITQRDIVGL--AFDRRWESGAHRRVLMHSPTAFDASTYESWVPLLRGGAVVVA 3239 Query: 254 PESVGSSPDDLHNLLITEKVSVLCQTPSAAGML---SPEGLESTTLI-VAGEACPTELVD 309 P S L LL T +V+ L T ++ SP L + G+ P E V Sbjct: 3240 PPGA-LSVAALEQLLATHEVTGLWLTAGLFRLVAEESPGALSGLREVWTGGDVVPAEAVR 3298 Query: 310 RW---APGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX---LFVLDKWLRP 363 R PG V+ + YGPTE T +A +S PL ++VLD LRP Sbjct: 3299 RVLAACPGIVVTDGYGPTETTTFA-LSHPLTAAEPVPARVPIGRPLDNTRVYVLDGSLRP 3357 Query: 364 APEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEY 423 P GV GELY+AG G+A GY RP TA RFVA PFG G RMYRTGDLVRW +DG +E+ Sbjct: 3358 VPAGVAGELYIAGAGLARGYTRRPAATAGRFVANPFGPPGARMYRTGDLVRWTADGVVEF 3417 Query: 424 LGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT-----GTA 478 GRAD+Q+K+RG+RIE GEI+ LA+ V QA V+ REDRPGD+RLVGY G A Sbjct: 3418 AGRADDQIKLRGFRIEPGEIEDRLARHPAVAQAAVLVREDRPGDRRLVGYAVLADPDGPA 3477 Query: 479 DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPA 538 A L L+ LP YMVP+A+V + +PLT NGK+DRRALPAPEY A + RAP Sbjct: 3478 TTADLTAYLSGELPDYMVPSALVAVAALPLTANGKIDRRALPAPEY-GGAQERRAPRDER 3536 Query: 539 EQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXX 597 E+ L +YA++LGV VG+DDSFFDLGG S+L+ ++V R R+A G + R +F T Sbjct: 3537 EKTLCALYAEILGVPEVGIDDSFFDLGGHSLLATRLVNRIRSAFGAEVPVRLVFEAPTVA 3596 Query: 598 XXXXXXXXXXESH---VVDEGVGPVVATPIMRWLREVDG----PTGQFNQTVITQAPAGV 650 + V E + + R L +D TG + + + V Sbjct: 3597 ALAGRLTGAEAAKQRLVPGERPAAIPLSHAQRRLWFIDSVEEDATGSYTIQLAVRLLGEV 3656 Query: 651 TEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVL 710 + + ++ RH +LR V ++ +L P+ V D L + Sbjct: 3657 DPGAMEAAVADVVGRHESLR-TVFPVEDGAPRQRILTPDEYTVPLPVEAVAEDGLEAALK 3715 Query: 711 VEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIAWA---QH 764 A + D AA + A +R + L L++HH+A DG S L DL +A+A + Sbjct: 3716 ESAASVFDLAADVPLRARLLRLAPREHVLDLVLHHIAADGSSLAPLARDLGLAYAARLER 3775 Query: 765 CTGQSIELPAGGTSFARWS-ALLAEHAKTDTV--RDLADAWRAVTSVPQALPPVQPDTDT 821 + LP +A W L + + ++ R LA A+ +P+ L + D Sbjct: 3776 TEPEFAPLPVQYADYALWQRRTLGDESDPESPYGRQLAHWRTALAGLPEEL-DLPVDRPR 3834 Query: 822 YVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNR----SDTPIGV 877 AG +++ ++ V G + +V A L+R +D P+G Sbjct: 3835 SAEAGSPGGQVELRFPDAVVEGVHRLADEGGASLFMVLHA-AVAATLHRVGGGTDIPVGT 3893 Query: 878 DVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLP 915 V G G D L VG+F + + P Sbjct: 3894 VVAGRG-------DEALDELVGFFVNTLVLRTDLSGAP 3924 Score = 365 bits (936), Expect = 7e-98 Identities = 236/575 (41%), Positives = 320/575 (55%), Gaps = 30/575 (5%) Query: 42 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRS 101 TI + FAE+V PDA A+ + Y ELD +NRLAH L G PG VA L RS Sbjct: 4084 TIVSRFAERVAAEPDAPAVSDRGVTIGYAELDARANRLAHRLIAAGVAPGDRVAVLQERS 4143 Query: 102 GEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADL-RSRLD-QYDLAV 159 + ++S L+VLK GAAY+P+D +P R+G ++ + LT L + +D ++ V Sbjct: 4144 ADLVVSTLAVLKAGAAYVPLDARYPLPRLGLIVEETGSRVLLTDRALSKVAVDGPAEVIV 4203 Query: 160 ID---MADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHAD 216 +D A + D P P D+LAY+ YTSG+TG PK + VTH NV A AD Sbjct: 4204 VDGGREAARSTDPDPGSPDIAPHQDELAYVMYTSGSTGKPKGIGVTHANVV----AFAAD 4259 Query: 217 LPSGPGQVWSQWHSL-VFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSV 275 G +HS FD S +EIW LL G LVV P + L L E ++ Sbjct: 4260 ERWRSGHEKVLFHSPHAFDASTYEIWATLLGGAHLVVAPPGQLDA-SGLRRLTEEEGLTA 4318 Query: 276 LCQTPSAAGMLSPE------GLESTTLIVAGEACPTELVDRWAPG---RVMINAYGPTEA 326 + T + +++ E GL + GE R +++ YGPTE Sbjct: 4319 VFMTTALFNLIAEEDPGAFAGLRE--IWTGGEQVSPAAFQRVLAACADTAVVHVYGPTET 4376 Query: 327 TIYAAMSEPLXXXXXXXXXXXXXXXXX---LFVLDKWLRPAPEGVVGELYVAGHGVATGY 383 T+YA + PL +VLD LRP P GV GELY+AG G A GY Sbjct: 4377 TVYA-LCVPLRAPVAALRTVPVGRPMDNTRAYVLDDRLRPVPFGVAGELYLAGAGTARGY 4435 Query: 384 IGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEI 443 G P +TA RF+A PFG GERMYRTGD+VR ++G +E++GRAD QVKIRG RIELGEI Sbjct: 4436 PGLPGMTAERFLADPFGAGGERMYRTGDVVRQDAEGLIEFVGRADHQVKIRGLRIELGEI 4495 Query: 444 QAALAKLDGVDQAVVIAREDRPGDKRLVGYITGT--ADPAQLRTALAESLPAYMVPTAVV 501 ++ L V + +V RED PGDK+LV Y+ AD A LR +A LP YMVP+A V Sbjct: 4496 ESVLQDQPQVSRTLVTVREDAPGDKKLVAYLVPVPGADTAGLREQVARRLPDYMVPSAFV 4555 Query: 502 VLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSF 561 L +P+ NGK+DR+ALPAP++ AA R P P E++L ++A+ L ++RVG+DD+F Sbjct: 4556 YLPDLPVNANGKVDRKALPAPDFGPAAGG-RGPRDPREELLCRLWAEALKLDRVGIDDNF 4614 Query: 562 FDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQT 595 F+LGGDSI+S+Q+ +R R+ G++ R +F T Sbjct: 4615 FELGGDSIVSLQLTSRVRSVFGVELSNRAVFQAPT 4649 Score = 241 bits (614), Expect = 1e-60 Identities = 150/439 (34%), Positives = 234/439 (53%), Gaps = 16/439 (3%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D+ PL+P+Q+G+LFH+ + G DVY +QL I + +D LR AV TV+ RH NL A Sbjct: 14 DIWPLSPLQKGMLFHALYEER-GADVYVIQLAIDLRRAVDAGVLRGAVATVLDRHENLRA 72 Query: 1151 RFVEQ-FGEPVQVLTADPMIAWRYLDLRGDDLTPDHE--IEQLCAAERSAVCDLLERPTF 1207 F + GEPVQ + + W D+ + P+ E + +L +R+ DL +RP Sbjct: 73 SFRNRKSGEPVQAILREAEPDWSETDI-SEVPEPEREARLRELLDEDRTRRFDL-KRPPL 130 Query: 1208 RAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH----RLPAAAPYRNFVNW 1263 R +L++ + ++RFV T HHI++DGWS+P++L E+ A Y LP PY+ ++ W Sbjct: 131 RFSLVKLAEEEYRFVFTAHHILLDGWSMPLVLGELMALYAAGGDAAELPPVIPYKEYLAW 190 Query: 1264 LXXXXXXXXXXXWREVLDGFETPTLVAPPGVPG--PRGIESYRVSAETTRALGELARSQH 1321 L W+ LDG PTLVA G P + V + + AL E ARS Sbjct: 191 LSRQDRPAAEAAWKAALDG-AAPTLVAGSGTGASLPDSLIE-EVDPKVSAALIERARSLG 248 Query: 1322 TTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSAD 1381 T+N+V+Q AW +L +TG+ DV FG VSGRP +L G E MVGL INT+P+R ++ + Sbjct: 249 VTLNSVVQTAWGLVLGSLTGRDDVVFGETVSGRPPELPGVERMVGLFINTLPVRLRLDSA 308 Query: 1382 TTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFM-GVQE 1440 ++ D + LQ D L H+HL L +I + G LFD + ++ +YPIDT + Sbjct: 309 LSLKDHVHHLQDAQADLLAHKHLGLAEIQQLHGAGPLFDAITIFANYPIDTDTLRNSADD 368 Query: 1441 LAVTEFNNREYNHYPLSVM-ALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDD 1499 + + HY L++ + G + +R+++ +F ++DR +L D Sbjct: 369 IGAVGAATVDATHYALNLEGTVRGDRMTVRLDHRPDLFTEGAGREVLDRLLAVLAEFADR 428 Query: 1500 PARRLSSMDVVDDDERTQL 1518 P R+ +++ D +R +L Sbjct: 429 PELRVGELELFDAADRARL 447 >tr|D1WS61|D1WS61_9ACTO Tax_Id=649189 SubName: Full=Amino acid adenylation domain protein;[Streptomyces sp. ACT-1] Length = 4935 Score = 1346 bits (3484), Expect = 0.0 Identities = 871/2174 (40%), Positives = 1169/2174 (53%), Gaps = 127/2174 (5%) Query: 3 AEPSTRTLLSFDLLDEDEHDQI-EVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALV 61 A+ R + DLL E + W + A P T ++ F P A ALV Sbjct: 1471 ADGPGRPAAALDLLTPAERRLVLGEWSDGA----PAFTEGSVAERFDAWAAARPRATALV 1526 Query: 62 SGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPV 121 + D+ TY EL ++RLAH L E GA P VA +PR+ + ++++L+VLK+GAAYLPV Sbjct: 1527 TEDQELTYAELAARTDRLAHWLREQGAGPERFVAVRLPRTVDLVVALLAVLKSGAAYLPV 1586 Query: 122 DPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPD 181 DPA P RI +++ DA+P+ LT ++ + D A A PA R P D Sbjct: 1587 DPALPADRIAYLLQDAQPLLVLTEEEMA----RADRAGAPTAAPAPARHP---------D 1633 Query: 182 DLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIW 241 AY+ YTSG+TG PK V V + L+ +L L P + ++ FD++V EI+ Sbjct: 1634 HPAYVIYTSGSTGRPKGVVVPGGGMVNLLDSLVRRLGLTPDDRTAAVSTVGFDIAVMEIF 1693 Query: 242 GALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLS---PEGLESTTLIV 298 L GG LV+ P++L LL +VL PS +L P+ L + Sbjct: 1694 LPLTSGGTLVLAGSDAVKDPEELGALLTRTGTTVLAAAPSLWHVLEETVPQALRGLRKMT 1753 Query: 299 AGEACPTELVDRW-APGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVL 357 GEA +L R A G + N YGPTE T+ A +E + VL Sbjct: 1754 GGEALAPDLARRLVALGGPVFNLYGPTEITVCATGAE--MDGVAPVTIGGPIGGTRVHVL 1811 Query: 358 DKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGS 417 D LRP P GV GELY+AG GV GY GRP LTA RFV P+G G RMYR+GDLVRWG Sbjct: 1812 DAALRPVPPGVPGELYIAGAGVTRGYHGRPGLTAERFVPDPYGPAGTRMYRSGDLVRWGD 1871 Query: 418 DGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT-- 475 +G+L+YLGR D QVK+RG+RIELGEI+ L + V +AVV E RPGD+RLV ++ Sbjct: 1872 EGRLDYLGRTDFQVKLRGFRIELGEIEEVLGGHEDVGRAVVGVHEFRPGDRRLVAHVMPA 1931 Query: 476 --GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRA 533 T D A LR A +LPAYMVP A VVLD +PL N K+DR+ALPAPE R Sbjct: 1932 EGRTVDAAVLREHAAAALPAYMVPAAFVVLDELPLNANAKVDRKALPAPE-TDGGEPSRE 1990 Query: 534 PSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVE 593 P E L ++A+VLG+ERV V +SFF +GGDSI S+Q+V RAR G++ PRD+F Sbjct: 1991 PRNATEATLCAIFAEVLGLERVDVAESFFAVGGDSISSIQLVGRARQEGLRFSPRDVFEH 2050 Query: 594 QTXXXXXXXXXXXXESHVV-----DEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPA 648 +T V + VG V TPI+ W+RE G QFNQT+ PA Sbjct: 2051 RTPQALAAAVLAEAAGPVAPDVSRSDAVGDVPLTPIVHWVRERGGAIDQFNQTMSLPVPA 2110 Query: 649 GVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA---- 704 G V +QA+LD H LR+R++ ED WSL + G V A +C+ VDA Sbjct: 2111 GTEPAAVASAVQAVLDHHDALRMRLDRLGEDFG-WSLEIDPPGTVRAEDCVHRVDAAALI 2169 Query: 705 ---LTD--------DVLVEARNRLDPAAGAMVSAVW----VRETSQLVLMIHHLAVDGVS 749 LT+ + + A+ RLDP AGAMV VW + +L ++ HHL VDGVS Sbjct: 2170 ASGLTEAELDLRAGEEIAAAQARLDPGAGAMVRCVWFDTGAKAPGRLTVIAHHLVVDGVS 2229 Query: 750 WRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAE-HAKTDTVRDLADAWRAV--- 805 WRILL DL A G+++ L GTSF WS L + A D +R+L WR + Sbjct: 2230 WRILLPDLQAALEALAAGRTVVLEPVGTSFRDWSRRLTDLAAAPDRMREL-PLWRDILDG 2288 Query: 806 TSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA-- 863 + P P+ DT+ TA QLS L + T LLG +PA F G+ D+LL A +A Sbjct: 2289 SDTPLTDRPLDAKRDTFGTAAQLSVQLPAKLTAPLLGRIPALFNTGINDVLLTALAVAVI 2348 Query: 864 -WTEFLNRSDTP-IGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVA 921 W R D P + +D+EGHGR +E+A VDLSRTVGWFT+ YP+ LT +P E+V + Sbjct: 2349 DWRGRTGRGDDPEVLIDLEGHGR-EEIADGVDLSRTVGWFTSLYPLRLTPGEMPGEEVWS 2407 Query: 922 GDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEVD--LGG-SDPTIGFNYLGRL---- 973 G A+G VK +KEQ R LP+ G+ +GLLR+LNP+ LG + P IGFNYLGRL Sbjct: 2408 GGPAVGRAVKRIKEQRRVLPDSGIGFGLLRHLNPQTAQVLGRFAQPQIGFNYLGRLGEAD 2467 Query: 974 -GAGAG---ELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWT 1029 GAG G E++ L + + M L H ++L A + +GP L A W Sbjct: 2468 DGAGTGREPEVNRGLSNVAE-----------AAMALPHALDLTATAVTYPDGPRLVAHWI 2516 Query: 1030 WAPSAFDEEQATRLSRLWFEALAGICAHVR--GGGGGLTPSDVAPARLTQRQIDEL-SQR 1086 WA F ++ L+R WF AL + H G GGL+PSD+ L Q +ID L S Sbjct: 2517 WAGELFSDDDMRDLARTWFRALEALVLHAERPEGAGGLSPSDLTLVDLGQEEIDRLASAG 2576 Query: 1087 YDVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHP 1146 DV DVLPL+P+Q+GLLFH+ + G D+Y L + G LD LRDA ++ RH Sbjct: 2577 DDVVDVLPLSPLQEGLLFHALYDER-GADIYTTLLAFELRGELDASALRDAAGALLRRHD 2635 Query: 1147 NLAARF-VEQFGEPVQVLTADPMIAWRYLDLRG-DDLTPDHEIEQLCAAERSAVCDLLER 1204 NL A F G+ +QV+ + WR +DL G D+ E+++L A + D + Sbjct: 2636 NLRAAFRPGAAGQSLQVIPRTVELPWRQVDLSGYDEERCTRELDRLTAQALAERFDPRQA 2695 Query: 1205 PTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIF----AGYFGHRLPAAAPYRNF 1260 P R L+RT HR +L HHI+ DGWS P+L E+F G LPA PY+++ Sbjct: 2696 PLLRFTLVRTGAKAHRLLLANHHILFDGWSGPVLSAELFELYRTGGDDAALPAVTPYKDY 2755 Query: 1261 VNWLXXXXXXXXXXXWREVLDGFETPTLVAPPG-VPGPRGIESYR--VSAETTRALGELA 1317 ++WL WRE LDG + PTLVAP P S+R +SA T AL A Sbjct: 2756 LSWLAGQDRAAAESAWREALDGVDEPTLVAPADPARAPLRPRSHRLELSAAETAALTGRA 2815 Query: 1318 RSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAK 1377 R T NTV+QAAW LL +TG+ DV FG V+GRPA+L G E+MVGL INT+P+R + Sbjct: 2816 RRSGVTKNTVVQAAWGLLLCGLTGREDVTFGETVNGRPAELPGVETMVGLFINTLPVRVR 2875 Query: 1378 VSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMG 1437 T+ D++ +L+ + L H++L L DI ++G LFDT + SYP+D+ Sbjct: 2876 AGRGDTLLDVVHRLRDQQLELLPHKYLGLTDIQRITGTGALFDTSTEFSSYPVDSETLER 2935 Query: 1438 VQE-LAVTEFNNREYNHYPLSVMAL-PGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEA 1495 E + + + ++ HYPL++ A G L L ++Y ++D E L R + +LEA Sbjct: 2936 TAEGIGIVDAQIQDGTHYPLALGATDDGRNLTLTIDYRPDLYDDGTAEALGARLRAILEA 2995 Query: 1496 MIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVT 1555 DP RR S+D++ + R L N P ++PE+F Q R P+APAV Sbjct: 2996 FAADPGRRADSLDLLTEAGRRTLLVERNDTAAEVPAG---AVPELFRAQARRTPDAPAVV 3052 Query: 1556 FEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPI 1615 F L+Y +LD +++LA LLA G P V +++ RSA+ V +LAVLK G AY+P+ Sbjct: 3053 FGDTRLDYRDLDARSDRLAGLLAGLGVGPETPVGVLMERSAELPVVLLAVLKAGGAYVPL 3112 Query: 1616 DPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPD 1675 + PA RL +L D VT G + V++ D + P T+L PD Sbjct: 3113 RDTDPAPRLRRLLADTGARVVVTDGASAPLAGELGVTVLDARDDSPAQAPRVTVL---PD 3169 Query: 1676 DIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIW 1735 +AY++YTSG+TG+PKGV IT ++ + +G FD S +E W Sbjct: 3170 QLAYVMYTSGSTGLPKGVEITQRDIVGL--AFDRRWESGAHRRVLMHSPTAFDASTYESW 3227 Query: 1736 GALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMM---SPEGLEGTALV- 1791 LL GG +V+ P A S L LL + V L+ T R++ SP L G V Sbjct: 3228 VPLLRGGAVVVAPPG-ALSVAALEQLLATHEVTGLWLTAGLFRLVAEESPGALSGLREVW 3286 Query: 1792 VAGEACPTEVVDRWAV---DRVMINAYGPTESTIYAAISAPLSPGSDV---VPIGSPVPK 1845 G+ P E V R V+ + YGPTE+T + A+S PL+ V VPIG P+ Sbjct: 3287 TGGDVVPAEAVRRVLAACPGIVVTDGYGPTETTTF-ALSHPLTAAEPVPARVPIGRPLDN 3345 Query: 1846 GATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGD 1905 +VLD LRPVP GV GELY+A T RFVA PFG PGARMYRTGD Sbjct: 3346 MRVYVLDGSLRPVPAGVAGELYIAGAGLARGYTRRPAATAGRFVANPFGPPGARMYRTGD 3405 Query: 1906 LVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLV 1965 LVRW DG +++ GRAD+Q+K+RG+RIE GEI+ L+ V QA V+ REDRPGD+RLV Sbjct: 3406 LVRWTADGVVEFAGRADDQIKLRGFRIEPGEIEDRLARHPAVAQAAVLVREDRPGDRRLV 3465 Query: 1966 GYIT-----GTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS 2020 GY G A A + L+ LP YMVP+A+V + LPLT NGK+DRRALPAPEY Sbjct: 3466 GYAVLADPDGPATTADLTAYLSGELPDYMVPSALVAVAALPLTANGKIDRRALPAPEYGG 3525 Query: 2021 AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLS 2080 A+ RAP E E+ L ++A +LGV A R+ + +A A++ Sbjct: 3526 AEERRAPRDERERALCALYAEILGVPEVGIDDSFFDLGGHSLLATRLVNRIRSAFGAEVP 3585 Query: 2081 VRTLFEAPTVAKLS 2094 VR +FEAPTVA L+ Sbjct: 3586 VRLVFEAPTVAALA 3599 Score = 1001 bits (2587), Expect = 0.0 Identities = 644/1633 (39%), Positives = 876/1633 (53%), Gaps = 92/1633 (5%) Query: 469 RLVGYITGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAA 528 RL+ + AD +LR E A A +VL +G DR A PA R A Sbjct: 417 RLLAVLAEFADRPELRVGELELFDA--ADRARLVLPP-----SGPADRAARPAGTDRPDA 469 Query: 529 NDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPR 588 D P+ E +L + A+VLGVE V V D+FF+ GGDSI S+Q+ RAR I R Sbjct: 470 ADGE-PANEREALLCRLVAEVLGVESVSVHDNFFERGGDSISSIQLAHRARKENIALTLR 528 Query: 589 DIFVEQTXXXXXXXXXXXXESH--VVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQA 646 +IF +T V D+GVGPV TP+M W + G FNQT+ Sbjct: 529 EIFEHRTVSRLAALAGAAPRPAPAVADDGVGPVPLTPVMHWQQSQGGRIDAFNQTLTVPV 588 Query: 647 PAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR------ 700 PAG+T+D + LQALLD H LR+R+ + EW+L V GAV A +C+R Sbjct: 589 PAGLTQDRLHTALQALLDHHDALRMRLG--RAPGQEWTLEVMARGAVRAEDCVRRYATGS 646 Query: 701 ---TVDALTDDVLVEARNRLDPAAGAMVSAVW----VRETSQLVLMIHHLAVDGVSWRIL 753 + ++ ++ A RL PA G MV AVW L L+IHHLAVDGVSWRIL Sbjct: 647 GDPAAERTHEEQVLAAVERLAPAEGRMVQAVWHDAGPDAEGLLALVIHHLAVDGVSWRIL 706 Query: 754 LEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQ--- 810 L DL A A +G I L GTS RWS LAE A T+ D WR V + P Sbjct: 707 LPDLEAALAALGSGDPIVLDPVGTSLRRWSRGLAEEALTERRVAELDLWRTVLATPDPHL 766 Query: 811 ALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA---WTEF 867 A P D A QL+ +L TT +LG VPA F AG + +L A LA W Sbjct: 767 ADRRTDPARDVVGAARQLTVTLPATTTAAVLGAVPALFHAGADEAMLTALALAVARWRRE 826 Query: 868 LNRSD-TPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALT--VENLPWEQVVAGDA 924 R + + + V +EGHGR +E+ VDLSRTVGWFT+ YPVA+ E+ +G Sbjct: 827 RGRGEGSAVLVGLEGHGR-EEILDGVDLSRTVGWFTSLYPVAVDPGAGADANEETWSGGP 885 Query: 925 ALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEVD---LGGSDPTIGFNYLGRLGAGAGEL 980 A+G KAVKEQLR++P+ G+ YGLLR+LNP+ G ++P IGFNYLGRLG + Sbjct: 886 AIGTAFKAVKEQLRAIPDKGMGYGLLRHLNPDTGPELAGCAEPQIGFNYLGRLGTADADA 945 Query: 981 SEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQA 1040 + R+ MPL +T+ELNA +D +G L ASWTW+ E + Sbjct: 946 DPDAVRVRDLTGAGD-----ASMPLPYTLELNAAAVDHTDGQRLTASWTWSGELLGEAEV 1000 Query: 1041 TRLSRLWFEALAGICAHV-RGGGGGLTPSDVAPARLTQRQIDELSQRYD-VTDVLPLTPV 1098 TR++RLWF+AL + AH R GGLTPSD+ +TQ +ID L + DVLPL+P+ Sbjct: 1001 TRIARLWFDALTALAAHAERPDAGGLTPSDLPLVTVTQAEIDRLETTPGGIVDVLPLSPL 1060 Query: 1099 QQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVE-QFG 1157 QQGL FH + DVY +Q + + G ++ LR+A ++ RH NL A FV G Sbjct: 1061 QQGLHFHGLYDAS-ETDVYTIQSVLELRGPVEPEALREAARALLRRHDNLRAFFVTGAAG 1119 Query: 1158 EPVQVLTADPMIAWRYLDLRG---DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRT 1214 P+QV+ A W DL G +D T E+E+L A++R DL P R L+R Sbjct: 1120 GPLQVIPAQAEPPWASHDLSGLADEDRTA--ELERLLASDRGTRFDLETSPPLRCTLVRL 1177 Query: 1215 SGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL---PA---AAPYRNFVNWLXXXX 1268 HRFVLT HHI +DGWS+P+L++++F Y H+ PA AAPY+ ++ WL Sbjct: 1178 GERDHRFVLTVHHIAVDGWSMPLLVRDLFDLYGSHQRGEEPAPSPAAPYKRYLTWLAAQD 1237 Query: 1269 XXXXXXXWREVLDGFETPT-LVAPPGVPGPRGIESYR--VSAETTRALGELARSQHTTIN 1325 WR L G + T LV G G E + E + L +AR T+N Sbjct: 1238 RGVSEDAWRTALAGLDEVTHLVTDAGAAGSAAPERLGTDIPEELSAGLTAVAREHGLTVN 1297 Query: 1326 TVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVG 1385 T++Q AW +L +TG+ DV FG VSGRP +L G E M+GL INT+P+R + ++ Sbjct: 1298 TLVQGAWGLVLSALTGRDDVVFGATVSGRPPELPGVEDMIGLFINTLPVRMDIDHGVSLA 1357 Query: 1386 DLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFM-GVQELAVT 1444 L ++LQ + + H++L L D+ ++G +LFDTL ++E+YP+++ QEL V Sbjct: 1358 GLFQRLQERQSGLMAHQYLGLADVQRLTGSGELFDTLVVFENYPVESEPLRESAQELGVV 1417 Query: 1445 EFNNREYNHYPLSVMALP-GHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARR 1503 + + HYP++++A G L + Y + D + +E + +RF +L A D P R Sbjct: 1418 DAEVHDAVHYPIALLAAQRGDRLTVEWSYRPDLLDRARVEAVAERFVAVLRAFADGPGRP 1477 Query: 1504 LSSMDVVDDDE-RTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLN 1562 +++D++ E R L EW++ A P + S+ E F P A A+ E + L Sbjct: 1478 AAALDLLTPAERRLVLGEWSDGA----PAFTEGSVAERFDAWAAARPRATALVTEDQELT 1533 Query: 1563 YGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAA 1622 Y EL ++LA+ L GA P + VA+ +PR+ D +VA+LAVLK+GAAYLP+DP++PA Sbjct: 1534 YAELAARTDRLAHWLREQGAGPERFVAVRLPRTVDLVVALLAVLKSGAAYLPVDPALPAD 1593 Query: 1623 RLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIY 1682 R+ ++L DA+P+ +T ++ +R D P P+ PD AY+IY Sbjct: 1594 RIAYLLQDAQPLLVLTEEEM-ARAD-------RAGAPTAAPAPAR-----HPDHPAYVIY 1640 Query: 1683 TSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGG 1742 TSG+TG PKGV + G + +LD+L L P + ++ FD++V EI+ L GG Sbjct: 1641 TSGSTGRPKGVVVPGGGMVNLLDSLVRRLGLTPDDRTAAVSTVGFDIAVMEIFLPLTSGG 1700 Query: 1743 RLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS---PEGLEGTALVVAGEACPT 1799 LV+ P++L ALL G VL PS ++ P+ L G + GEA Sbjct: 1701 TLVLAGSDAVKDPEELGALLTRTGTTVLAAAPSLWHVLEETVPQALRGLRKMTGGEALAP 1760 Query: 1800 EVVDRW-AVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPV 1858 ++ R A+ + N YGPTE T+ A + G V IG P+ VLD LRPV Sbjct: 1761 DLARRLVALGGPVFNLYGPTEITVCA--TGAEMDGVAPVTIGGPIGGTRVHVLDAALRPV 1818 Query: 1859 PPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYL 1918 PPGV GELY+A LT RFV P+G G RMYR+GDLVRWGD+G+L YL Sbjct: 1819 PPGVPGELYIAGAGVTRGYHGRPGLTAERFVPDPYGPAGTRMYRSGDLVRWGDEGRLDYL 1878 Query: 1919 GRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADP 1974 GR D QVK+RG+RIELGEI+ L + V +AVV E RPGD+RLV ++ T D Sbjct: 1879 GRTDFQVKLRGFRIELGEIEEVLGGHEDVGRAVVGVHEFRPGDRRLVAHVMPAEGRTVDA 1938 Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKT 2034 A R LPAYMVPAA V L+ LPL N K+DR+ALPAPE + R P TE T Sbjct: 1939 AVLREHAAAALPAYMVPAAFVVLDELPLNANAKVDRKALPAPETDGGEPSREPRNATEAT 1998 Query: 2035 LAGIFAHVLGVER 2047 L IFA VLG+ER Sbjct: 1999 LCAIFAEVLGLER 2011 Score = 442 bits (1138), Expect = e-121 Identities = 361/1135 (31%), Positives = 523/1135 (46%), Gaps = 108/1135 (9%) Query: 1033 SAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDV 1092 SAF E RL FEA V G LT ++ A RL + Sbjct: 3578 SAFGAEVPVRLV---FEAPT-----VAALAGRLTGAEAAKQRLVPGERPT---------A 3620 Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ Q+ L F + Y +QL + + G +D + AV VV RH +L F Sbjct: 3621 IPLSHAQRRLWFIDSVEEDATGS-YTIQLAVRLLGEVDPGAMEAAVADVVGRHESLRTVF 3679 Query: 1153 VEQFGEPVQ-VLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAAL 1211 + G P Q +LT D ++ +D +E ++V DL RA L Sbjct: 3680 PVEDGAPRQRILTPDEYTVPLPVEAVAED-----GLEAALKESAASVFDLAADVPLRARL 3734 Query: 1212 IRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNWL 1264 +R + +H L HHI DG SL L +++ Y R P AP Y ++ W Sbjct: 3735 LRLAPREHVLDLVLHHIAADGSSLAPLARDLGLAYAARLEGREPEFAPLPVQYADYALWQ 3794 Query: 1265 XXXXXXXXXXX---------WREVLDGFETPTLVAPPGVP------GPRGIESYRVSAET 1309 WR L G L P P P G R Sbjct: 3795 RRTLGDESDPESPYGRQLGHWRTALAGLPEE-LDLPVDRPRSAEAGNPGGQVELRFPDAV 3853 Query: 1310 TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLI 1369 + LA ++ VL AA L R+ G D+ GT V+GR + + +VG + Sbjct: 3854 VEGVHRLADEGGASLFMVLHAAVAATLHRVGGGTDIPVGTVVAGRGDE--ALDELVGFFV 3911 Query: 1370 NTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQLFDTLF 1423 NT+ +R +S +LLR++++ H+ + + + G LF Sbjct: 3912 NTLVLRTDLSGAPDFRELLRRVRNTDLTAFSHQDVPFDRLVEELNPARSLGRNPLFQVAV 3971 Query: 1424 LYESY-------------PIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRV 1470 E+ P T+A + +L+ T F + P LG ++ Sbjct: 3972 SLENNEEADLELPGLTLAPQPTTADLAKFDLSFT-FGEIRPDSGPAG--------LGGQL 4022 Query: 1471 EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQP 1530 +Y+ ++FD S E L DR RLL A++ DP ++ +D++ ERT L E N +P Sbjct: 4023 DYNAALFDHSTAEALADRLVRLLAAVVADPGLPVADVDLLSPRERTVLRE-RNDTARARP 4081 Query: 1531 VDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVAL 1590 + I FA +V +P+APAV+ G ++ Y ELD AN+LA+ L G APG VA+ Sbjct: 4082 AGT---IVSRFAERVAAEPDAPAVSDRGVTIGYAELDARANRLAHRLIAAGVAPGDRVAV 4138 Query: 1591 MVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFD 1650 + RSAD +V+ LAVLK GAAY+P+D P RL ++ + +T L Sbjct: 4139 LQERSADLVVSTLAVLKAGAAYVPLDARYPLPRLGLIVEETGSRVLLTDRALSKVAVDGP 4198 Query: 1651 LQVVEVDDPAVEIYPSTTLLTPSPD------DIAYMIYTSGTTGVPKGVAITHGNVTQVL 1704 +V+ VD E ST SPD ++AY++YTSG+TG PKG+ +TH NV Sbjct: 4199 AEVIVVDGGR-EAARSTDPDPGSPDIALHQEELAYVMYTSGSTGKPKGIGVTHANVV--- 4254 Query: 1705 DTLPAELPAGPGAVWSQWHSL-VFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLV 1763 A+ G +HS FD S +EIW LL G LV+ P + L L Sbjct: 4255 -AFAADERWRSGHEKVLFHSPHAFDASTYEIWATLLGGAHLVVAPPGQLDA-SGLRRLTE 4312 Query: 1764 SEGVNVLYQTPSAVRMMSPEGLEGTA----LVVAGEACPTEVVDRW---AVDRVMINAYG 1816 EG+ ++ T + +++ E A + GE R D +++ YG Sbjct: 4313 EEGLTAVFMTTALFNLIAEEDPGAFAGLREIWTGGEQVSPAAFQRVLAACADTAVVHVYG 4372 Query: 1817 PTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXX 1873 PTE+T+YA + AP++ VP+G P+ +VLD+ LRPVP GV GELYLA Sbjct: 4373 PTETTVYALCVPLRAPVA-ALRTVPVGRPMDNTRAYVLDDRLRPVPFGVAGELYLAGAGT 4431 Query: 1874 XXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIE 1933 +T RF+A PFG G RMYRTGD+VR +G ++++GRAD QVKIRG RIE Sbjct: 4432 ARGYPGLPGMTAERFLADPFGAGGERMYRTGDVVRQDAEGLIEFVGRADHQVKIRGLRIE 4491 Query: 1934 LGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGT--ADPAAARSELTNRLPAYMVP 1991 LGEI++ L D V + +V RED PGDK+LV Y+ AD A R ++ RLP YMVP Sbjct: 4492 LGEIESVLQDQPQVSRTLVTVREDAPGDKKLVAYLVPVPGADTAGLREQVARRLPDYMVP 4551 Query: 1992 AAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXX 2051 +A V L LP+ NGK+DR+ALPAP++ A P E+ L ++A L ++R Sbjct: 4552 SAFVYLPDLPVNANGKVDRKALPAPDFGPAAGGSGPRDPREELLCRLWAEALKLDRVGID 4611 Query: 2052 XXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTD 2106 ++++T+ V + +LS R +F+APTVA L + V G+R D Sbjct: 4612 DNFFELGGDSIVSLQLTSRVRSVFGVELSNRAVFQAPTVASL-MEVMGAGGQRDD 4665 Score = 411 bits (1057), Expect = e-112 Identities = 320/938 (34%), Positives = 447/938 (47%), Gaps = 59/938 (6%) Query: 19 DEHDQIEVWGNRAVLTDPGPTPVTIPA-----LFAEQVVRAPDAVALVSGDRSWTYRELD 73 D D + G R +L + T +PA LF Q R PDA A+V GD YR+LD Sbjct: 3005 DSLDLLTEAGRRTLLVERNDTAAEVPAGAVPELFRAQARRTPDAPAVVFGDTRLDYRDLD 3064 Query: 74 EASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFM 133 S+RLA +LA G P V L+ RS E + +L+VLK G AY+P+ P R+ + Sbjct: 3065 ARSDRLAGLLAGLGVGPETPVGVLMERSAELPVVLLAVLKAGGAYVPLRDTDPAPRLRRL 3124 Query: 134 MSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTT 193 ++D +T + + V+D D + + P + PD LAY+ YTSG+T Sbjct: 3125 LADTGARVVVTDGASAPLAGELGVTVLDARDDSPAQAPRVTVL---PDQLAYVMYTSGST 3181 Query: 194 GVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVV 253 G+PK V +T ++ L A SG + FD S +E W LL GG +VV Sbjct: 3182 GLPKGVEITQRDIVGL--AFDRRWESGAHRRVLMHSPTAFDASTYESWVPLLRGGAVVVA 3239 Query: 254 PESVGSSPDDLHNLLITEKVSVLCQTPSAAGML---SPEGLESTTLI-VAGEACPTELVD 309 P S L LL T +V+ L T ++ SP L + G+ P E V Sbjct: 3240 PPGA-LSVAALEQLLATHEVTGLWLTAGLFRLVAEESPGALSGLREVWTGGDVVPAEAVR 3298 Query: 310 RW---APGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX---LFVLDKWLRP 363 R PG V+ + YGPTE T +A +S PL ++VLD LRP Sbjct: 3299 RVLAACPGIVVTDGYGPTETTTFA-LSHPLTAAEPVPARVPIGRPLDNMRVYVLDGSLRP 3357 Query: 364 APEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEY 423 P GV GELY+AG G+A GY RP TA RFVA PFG G RMYRTGDLVRW +DG +E+ Sbjct: 3358 VPAGVAGELYIAGAGLARGYTRRPAATAGRFVANPFGPPGARMYRTGDLVRWTADGVVEF 3417 Query: 424 LGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT-----GTA 478 GRAD+Q+K+RG+RIE GEI+ LA+ V QA V+ REDRPGD+RLVGY G A Sbjct: 3418 AGRADDQIKLRGFRIEPGEIEDRLARHPAVAQAAVLVREDRPGDRRLVGYAVLADPDGPA 3477 Query: 479 DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPA 538 A L L+ LP YMVP+A+V + +PLT NGK+DRRALPAPEY A + RAP Sbjct: 3478 TTADLTAYLSGELPDYMVPSALVAVAALPLTANGKIDRRALPAPEY-GGAEERRAPRDER 3536 Query: 539 EQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXX 597 E+ L +YA++LGV VG+DDSFFDLGG S+L+ ++V R R+A G + R +F T Sbjct: 3537 ERALCALYAEILGVPEVGIDDSFFDLGGHSLLATRLVNRIRSAFGAEVPVRLVFEAPTVA 3596 Query: 598 XXXXXXXXXXESH---VVDEGVGPVVATPIMRWLREVDG----PTGQFNQTVITQAPAGV 650 + V E + + R L +D TG + + + V Sbjct: 3597 ALAGRLTGAEAAKQRLVPGERPTAIPLSHAQRRLWFIDSVEEDATGSYTIQLAVRLLGEV 3656 Query: 651 TEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVL 710 + + ++ RH +LR V ++ +L P+ V D L + Sbjct: 3657 DPGAMEAAVADVVGRHESLR-TVFPVEDGAPRQRILTPDEYTVPLPVEAVAEDGLEAALK 3715 Query: 711 VEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIAWAQHCTG 767 A + D AA + A +R + L L++HH+A DG S L DL +A+A G Sbjct: 3716 ESAASVFDLAADVPLRARLLRLAPREHVLDLVLHHIAADGSSLAPLARDLGLAYAARLEG 3775 Query: 768 QSIE---LPAGGTSFARWS-ALLAEHAKTDTV--RDLADAWRAVTSVPQALPPVQPDTDT 821 + E LP +A W L + + ++ R L A+ +P+ L + D Sbjct: 3776 REPEFAPLPVQYADYALWQRRTLGDESDPESPYGRQLGHWRTALAGLPEEL-DLPVDRPR 3834 Query: 822 YVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNR----SDTPIGV 877 AG +++ ++ V G + +V A L+R +D P+G Sbjct: 3835 SAEAGNPGGQVELRFPDAVVEGVHRLADEGGASLFMVLHA-AVAATLHRVGGGTDIPVGT 3893 Query: 878 DVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLP 915 V G G D L VG+F + + P Sbjct: 3894 VVAGRG-------DEALDELVGFFVNTLVLRTDLSGAP 3924 Score = 357 bits (916), Expect = 1e-95 Identities = 233/575 (40%), Positives = 318/575 (55%), Gaps = 30/575 (5%) Query: 42 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRS 101 TI + FAE+V PDA A+ + Y ELD +NRLAH L G PG VA L RS Sbjct: 4084 TIVSRFAERVAAEPDAPAVSDRGVTIGYAELDARANRLAHRLIAAGVAPGDRVAVLQERS 4143 Query: 102 GEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADL-RSRLD-QYDLAV 159 + ++S L+VLK GAAY+P+D +P R+G ++ + LT L + +D ++ V Sbjct: 4144 ADLVVSTLAVLKAGAAYVPLDARYPLPRLGLIVEETGSRVLLTDRALSKVAVDGPAEVIV 4203 Query: 160 ID---MADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHAD 216 +D A + D P ++LAY+ YTSG+TG PK + VTH NV A AD Sbjct: 4204 VDGGREAARSTDPDPGSPDIALHQEELAYVMYTSGSTGKPKGIGVTHANVV----AFAAD 4259 Query: 217 LPSGPGQVWSQWHSL-VFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSV 275 G +HS FD S +EIW LL G LVV P + L L E ++ Sbjct: 4260 ERWRSGHEKVLFHSPHAFDASTYEIWATLLGGAHLVVAPPGQLDA-SGLRRLTEEEGLTA 4318 Query: 276 LCQTPSAAGMLSPE------GLESTTLIVAGEACPTELVDRWAPG---RVMINAYGPTEA 326 + T + +++ E GL + GE R +++ YGPTE Sbjct: 4319 VFMTTALFNLIAEEDPGAFAGLRE--IWTGGEQVSPAAFQRVLAACADTAVVHVYGPTET 4376 Query: 327 TIYAAMSEPLXXXXXXXXXXXXXXXXX---LFVLDKWLRPAPEGVVGELYVAGHGVATGY 383 T+YA + PL +VLD LRP P GV GELY+AG G A GY Sbjct: 4377 TVYA-LCVPLRAPVAALRTVPVGRPMDNTRAYVLDDRLRPVPFGVAGELYLAGAGTARGY 4435 Query: 384 IGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEI 443 G P +TA RF+A PFG GERMYRTGD+VR ++G +E++GRAD QVKIRG RIELGEI Sbjct: 4436 PGLPGMTAERFLADPFGAGGERMYRTGDVVRQDAEGLIEFVGRADHQVKIRGLRIELGEI 4495 Query: 444 QAALAKLDGVDQAVVIAREDRPGDKRLVGYITGT--ADPAQLRTALAESLPAYMVPTAVV 501 ++ L V + +V RED PGDK+LV Y+ AD A LR +A LP YMVP+A V Sbjct: 4496 ESVLQDQPQVSRTLVTVREDAPGDKKLVAYLVPVPGADTAGLREQVARRLPDYMVPSAFV 4555 Query: 502 VLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSF 561 L +P+ NGK+DR+ALPAP++ AA P P E++L ++A+ L ++RVG+DD+F Sbjct: 4556 YLPDLPVNANGKVDRKALPAPDFGPAAGG-SGPRDPREELLCRLWAEALKLDRVGIDDNF 4614 Query: 562 FDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQT 595 F+LGGDSI+S+Q+ +R R+ G++ R +F T Sbjct: 4615 FELGGDSIVSLQLTSRVRSVFGVELSNRAVFQAPT 4649 Score = 241 bits (614), Expect = 1e-60 Identities = 149/439 (33%), Positives = 234/439 (53%), Gaps = 16/439 (3%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D+ PL+P+Q+G+LFH+ + G DVY +QL I + +D LR AV TV+ RH NL A Sbjct: 14 DIWPLSPLQKGMLFHALYEER-GADVYVIQLAIDLRRAVDAGVLRGAVATVLDRHENLRA 72 Query: 1151 RFVEQ-FGEPVQVLTADPMIAWRYLDLRGDDLTPDHE--IEQLCAAERSAVCDLLERPTF 1207 F + GEPVQ + + W D+ + P+ E + +L +R+ DL +RP Sbjct: 73 SFRNRKSGEPVQAILREAEPDWSETDI-SEVPEPEREARLRELLDEDRTRRFDL-KRPPL 130 Query: 1208 RAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH----RLPAAAPYRNFVNW 1263 R +L++ + ++RFV T HHI++DGWS+P++L E+ A Y LP PY+ ++ W Sbjct: 131 RFSLVKLADEEYRFVFTAHHILLDGWSMPLVLGELMALYAAGGDAAELPPVIPYKEYLAW 190 Query: 1264 LXXXXXXXXXXXWREVLDGFETPTLVAPPGVPG--PRGIESYRVSAETTRALGELARSQH 1321 + W+ LDG PTLVA G P + V + + AL E ARS Sbjct: 191 ISRQDRPAAEAAWKAALDG-AAPTLVAGSGTGASLPDSLIE-EVDPKVSAALIERARSLG 248 Query: 1322 TTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSAD 1381 T+N+V+Q AW +L +TG+ DV FG VSGRP +L G E MVGL INT+P+R ++ + Sbjct: 249 VTLNSVVQTAWGLVLGSLTGRDDVVFGETVSGRPPELPGVERMVGLFINTLPVRLRLDSA 308 Query: 1382 TTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFM-GVQE 1440 ++ D + LQ D L H+HL L +I + G LFD + ++ +YPIDT + Sbjct: 309 LSLKDHVHNLQDAQADLLAHKHLGLAEIQQLHGAGPLFDAITIFANYPIDTDTLQNSADD 368 Query: 1441 LAVTEFNNREYNHYPLSVM-ALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDD 1499 + + HY L++ + G + +R+++ +F ++DR +L D Sbjct: 369 IGAVGAATVDATHYALNLEGTVRGDRMTVRLDHRPDLFTEGAGREVLDRLLAVLAEFADR 428 Query: 1500 PARRLSSMDVVDDDERTQL 1518 P R+ +++ D +R +L Sbjct: 429 PELRVGELELFDAADRARL 447 >tr|Q0S6F3|Q0S6F3_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal peptide synthetase;[Rhodococcus sp.] Length = 8939 Score = 1345 bits (3480), Expect = 0.0 Identities = 856/2180 (39%), Positives = 1159/2180 (53%), Gaps = 134/2180 (6%) Query: 28 GNRAVLTD----PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVL 83 G RA LT PG T+P + P AVALVS R +YR+LDE SNRLA +L Sbjct: 2877 GERAALTSASGGPGVAARTLPQMLTAAAAADPAAVALVSDGRQVSYRDLDEWSNRLARLL 2936 Query: 84 AEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAAL 143 E G P VA +PRS E++L++ SV KTGAA+LPVDP HP RI +M+ D+ VA L Sbjct: 2937 IERGVGPEQVVALALPRSIESVLAVWSVAKTGAAFLPVDPNHPAERIEYMLGDSGAVAGL 2996 Query: 144 TTADLRSRLD-------------QYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTS 190 TTA LRS L + +LA++ PA +D S D AY+ YTS Sbjct: 2997 TTAALRSALPASIPWLVPGDPETEAELALL----PAAAVTDADRTSALHVDHPAYVIYTS 3052 Query: 191 GTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRL 250 G+TG PK V TH + + + + S FD SV E+ A+ G + Sbjct: 3053 GSTGKPKGVVTTHRGLANFAATEQNTFGTTAASRTLHFASPSFDASVLELMLAIGPGATM 3112 Query: 251 VVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG-EACPTELVD 309 V+ SV D+L LL+ E+V+ TP+A + P GLES +V G E CP ELV Sbjct: 3113 VIASPSVYGG-DELAELLLRERVTHCFVTPAALASVDPAGLESVQCVVTGGETCPPELVA 3171 Query: 310 RWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVV 369 RWAPGR M +AYGPTE+T+ +++S PL VLD+ L P P GV Sbjct: 3172 RWAPGRAMFDAYGPTESTVVSSISTPLAPGEPVTIGAPTLGFTAA-VLDQRLHPVPAGVA 3230 Query: 370 GELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADE 429 GELY+AG +A GY GR LTA RFVA PFG G RMYRTGDLVRW +DGQL+YLGR D Sbjct: 3231 GELYLAGPALARGYHGRYPLTAERFVANPFGPPGSRMYRTGDLVRWTADGQLDYLGRTDF 3290 Query: 430 QVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRT 485 QVKIRG+RIELGE+++AL V AV R D RL+GY+ DP ++ Sbjct: 3291 QVKIRGFRIELGEVESALLAHGDVAAAVADVRRDERSGDRLIGYVVPEPGADIDPGEVLQ 3350 Query: 486 ALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADV 545 L +YMVP AVVV+ +P+TV+GKLDR+ALP P++ D R P T E +LA + Sbjct: 3351 FAGTRLASYMVPAAVVVIAALPVTVHGKLDRKALPEPDFGVVVTDSRPPRTETEALLAGL 3410 Query: 546 YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXX 605 + VLG+ VG+DDSFF LGGDSI+S+Q+VARA+AAG+ PRD+F +T Sbjct: 3411 FRDVLGLGSVGMDDSFFALGGDSIMSIQLVARAKAAGLILSPRDVFERRTVAGLAEVAHY 3470 Query: 606 XXESHVVDE-----GVGPVVATPIMRW-LREVDGPTGQFNQTVITQAPAGVTEDDVVVIL 659 VV E GVGPV TP++ W L G +F+Q V+ AP +T DD+ + Sbjct: 3471 ERADAVVLEELPGAGVGPVPLTPVVAWMLGRSGGRLNRFSQAVLVTAPPRLTRDDLAAAV 3530 Query: 660 QALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTV----------DALTDDV 709 A+LDRH LR R+ +++ +W++ V G+V A + V DA+ Sbjct: 3531 DAVLDRHDMLRARL--AVDESGQWAMTVLPTGSVPADALIHHVPVTSFDAGDFDAVARAE 3588 Query: 710 LVEARNRLDPAAGAMVSAVWV---RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCT 766 L A +RLDPA+ +MV +W +L+L+ HHL VDGVSWRIL+ DL A A+ Sbjct: 3589 LNAAADRLDPASASMVQVLWFDGPGGQGRLLLVAHHLVVDGVSWRILIADLAAAHARAAE 3648 Query: 767 GQSIELPAGGTSFARWSALLAEHAKTDTV---RDLADAWRAVTSVPQAL---PPVQPDTD 820 G LPA GTS RWS H TD R A W+++ P L P+ P D Sbjct: 3649 GLPAALPAVGTSMRRWS-----HGLTDAAAARRTEAGRWQSILDGPDPLLGFRPLDPAVD 3703 Query: 821 TYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA---WTEFLNRSDTPIGV 877 T G++S + T LL +PAAF V D LL A +A W + + Sbjct: 3704 VDATTGRVSVDVPPPVTEALLTTLPAAFHGTVGDGLLTALTMAMIRWRRLRGVETADVLI 3763 Query: 878 DVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQL 937 ++EGHGR D + DLSRTVGWFTT +P L + + + +AGD A G +KA+KEQL Sbjct: 3764 NLEGHGREDHVVPGADLSRTVGWFTTLFPARLDLTGIGIDAALAGDDAAGTAIKAIKEQL 3823 Query: 938 RSLPE-GLTYGLLRYLNP---EVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXX 993 ++P+ G+ YG+LRYL+P E P + FNYLGR+ G++S W + Sbjct: 3824 LAIPDHGIGYGILRYLDPVGSEALRRFRPPQVSFNYLGRVATSGGDVS---W-LPVAGSG 3879 Query: 994 XXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAG 1053 MP V++NA T D P L A+W++ E LS LW L Sbjct: 3880 DLGGTQNYDMPAAWVVDVNAATTVRDGAPVLTATWSYPTGVLAAEDVEELSALWIRGLTA 3939 Query: 1054 ICAHV-RGGGGGLTPSDVAPARLTQRQIDELSQRY-DVTDVLPLTPVQQGLLFHSTFARG 1111 + H R G GGLTPSD+ + Q I+ Y D+ D+ PL+P+Q GLLFH+ + Sbjct: 3940 LAEHASRPGAGGLTPSDLDLVSVGQADIERFESAYPDLADIWPLSPLQAGLLFHAQLSEH 3999 Query: 1112 IGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAW 1171 D Y VQL + + G +D RLR A ++ RH NL F + PVQV+ A W Sbjct: 4000 -RLDAYQVQLVLDLRGTVDSARLRRAAQGLLDRHANLRVAFADTGAGPVQVVLAGATAPW 4058 Query: 1172 RYLDLRG-DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVI 1230 +DL D E E L AA+R+ ++ E P R L+RT+ +++R V+T HHI++ Sbjct: 4059 TDVDLSDLADTRIAAEAEALVAADRAVPFEMSEAPLLRFTLLRTAPDRYRLVVTHHHILL 4118 Query: 1231 DGWSLPILLQEIFAGYFGH----RLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETP 1286 DGWS P++++++ Y LP YR+++ W+ W L G + P Sbjct: 4119 DGWSTPLVIKDLLILYATDGDTTALPRVTSYRDYLQWIGRQDHERSTAAWVSALAGSDEP 4178 Query: 1287 TLVAPPGVPGPRGIESYR--------VSAETTRALGELARSQHTTINTVLQAAWTQLLMR 1338 T VA P RG +S+ V E TRAL LAR T+NT++Q AW +L Sbjct: 4179 TFVA----PAARGEQSFAEPEDVRLDVGEEKTRALEALAREHGLTMNTLVQVAWGLVLTT 4234 Query: 1339 MTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDT 1398 + + DV FG VSGRP +AG ESMVGL INTVP+R ++ + T+ +LL++ Q + Sbjct: 4235 LGTREDVVFGATVSGRPPGVAGIESMVGLFINTVPVRLRLRREETLAELLQRFQREQSAL 4294 Query: 1399 LEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQE------LAVTEFNNREYN 1452 L+H ++ L +I G FDTL ++ESYP+D MG+ E + V + Sbjct: 4295 LDHHYVGLTEIQRAVGEGAAFDTLTVFESYPVDR---MGLSEDTDIDGMHVAGIEGIDST 4351 Query: 1453 HYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDD 1512 HYP ++MA L LR+ Y +VF E++ R R+++ ++ D ++ + ++ + Sbjct: 4352 HYPFTLMAHVDTGLHLRLRYQPNVFRSEFAESVAARVARVVQILLSDIETPIAHLTLLSE 4411 Query: 1513 DERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQ 1572 E L E+ AV P P+++PE+ PEA A+ +G +Y ELDE ++ Sbjct: 4412 AE---LQEYT--AVSGAPAGPPKTLPEILTASAGNRPEAAALVCDGRETSYRELDERSSA 4466 Query: 1573 LANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAK 1632 LA +L GA P VAL +PRS ++++A+ AV K GAA++P+DP+ PA R+E ML D+ Sbjct: 4467 LARVLIERGAGPETFVALGLPRSRESVLAVWAVAKAGAAFVPVDPNYPADRIEHMLADSG 4526 Query: 1633 PVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSP--------------DDIA 1678 VT R R G + + +DD A + T SP D A Sbjct: 4527 AALGVTMSAHRHRLPG-SVPWLVLDDAAFD----RTWAAASPVRVTDLDRRSVLDVDHAA 4581 Query: 1679 YMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGAL 1738 Y IYTSG+TG PKGV +TH + +L P + S FDV++ E+ + Sbjct: 4582 YAIYTSGSTGRPKGVVVTHRGLANLLTEQTEHYTVSPDSRCLHICSPSFDVAILELVQSC 4641 Query: 1739 LHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG-TALVVAGEAC 1797 G LVI P + G +L ALL E V TP+ + + +G+E ALVVAG+A Sbjct: 4642 AAGATLVIAPPDVYGGA-ELAALLRRERVTHACITPAVLATVERDGIEHLEALVVAGDAV 4700 Query: 1798 PTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRP 1857 E+V W DR M N YGPTE+TI S P+ PG + V IG PV A VLD L+P Sbjct: 4701 GDELVAAWGADRAMFNGYGPTEATILTTFSRPMRPG-EPVTIGGPVRGIALSVLDARLQP 4759 Query: 1858 VPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQY 1917 VP GV GELY+A LT RFVA P+G G RMYRTGD+VRW D L+Y Sbjct: 4760 VPAGVPGELYIAGPALARGYHRRPALTAERFVADPYG--GGRMYRTGDVVRWSRDHTLEY 4817 Query: 1918 LGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAA 1977 LGR+D QVKIRG R+ELGEI + L+ +D A + R GD LV Y+ A Sbjct: 4818 LGRSDFQVKIRGQRVELGEIDSVLTTHPHLDFAATLGRPGPLGDTALVSYVLPHDGEEVA 4877 Query: 1978 RSELT----NRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQ-RYRAPETETE 2032 E+ LP YMVPAAVV L+ +PLT GKLDR+ALPAPE+ SA YRAP T E Sbjct: 4878 APEVLAFAGRILPKYMVPAAVVVLDEIPLTPVGKLDRKALPAPEFTSATIGYRAPTTPVE 4937 Query: 2033 KTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAK 2092 + +A +FA VLG R A R A +N+ALDA + V LF+AP VA Sbjct: 4938 EAVAQVFADVLGAPRVGADDSFFELGGDSLSATRAVARINSALDAGIGVAALFDAPVVAD 4997 Query: 2093 LSLHVEHDAGERTDRVSFAA 2112 L++ ++ T V+ AA Sbjct: 4998 LAVRIDSAVTAATPSVALAA 5017 Score = 1337 bits (3461), Expect = 0.0 Identities = 849/2198 (38%), Positives = 1195/2198 (54%), Gaps = 137/2198 (6%) Query: 14 DLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELD 73 ++LD E D + +P T+ LF R+ A A+V S TY ELD Sbjct: 5464 EILDTAERDLV-----LPPFAEPPAPDATLAELFERAAQRSRHATAVVCEGVSLTYDELD 5518 Query: 74 EASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFM 133 +NRLA +L GA P VA RS E ++++L+V+K+GA Y+PVD +P R+ F+ Sbjct: 5519 TRANRLARLLIARGAGPETLVAVAAARSVELVVALLAVVKSGAGYVPVDVTYPAERLAFV 5578 Query: 134 MSDAKPVAALTTADLRS--RLDQYDLAVIDMADPAIDRRPSDAL-------SGP-RPDDL 183 +DA+PV LTT R L ++D A+ + + L +GP RPD + Sbjct: 5579 FADARPVCVLTTEAESDAVRASGVPLLLVDSAETVAELDRTSPLPVTDGDRTGPLRPDSV 5638 Query: 184 AYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGA 243 AY+ YTSG+TG PK V V H NV L + VW+ +HS FD SVWE+WGA Sbjct: 5639 AYVIYTSGSTGQPKGVQVAHRNVVTLFANTQPLFRFDACDVWTMFHSAAFDFSVWELWGA 5698 Query: 244 LLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEG-------LESTTL 296 LLHGGRLVVV SPD LL E V+VL QTP+A L+ L + Sbjct: 5699 LLHGGRLVVVDYFTTRSPDMFLRLLRDENVTVLNQTPTAFYQLAEADRVAGATELSLRVV 5758 Query: 297 IVAGEACPTELVDRWAPGRV-----MINAYGPTEATIYAA---MSEPLXXXXXXXXXXXX 348 + GEA + RW V ++N YG TE T++ + + L Sbjct: 5759 VFGGEALDLGQLTRWYARHVDTAPALVNMYGITETTVHVSHLPLDAELAASASASVIGRA 5818 Query: 349 XXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYR 408 ++VLD L P P GVVGELYV+G V+ GY+GR LT++RFVA P G RMYR Sbjct: 5819 LPGLRVYVLDSRLHPVPPGVVGELYVSGPQVSRGYLGRFALTSTRFVADPH-TPGSRMYR 5877 Query: 409 TGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDK 468 +GDL RW +DGQLEYLGR D QV+++G+RIELGE+++AL +GV Q+VV+AR +R Sbjct: 5878 SGDLGRWNADGQLEYLGRNDFQVQVKGFRIELGEVESALLACEGVAQSVVLARRER---- 5933 Query: 469 RLVGYITGTA----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEY 524 LVGY+ A DPA + A+A L A+MVP AVVVLD +PLTVNGKLDRRALP P++ Sbjct: 5934 -LVGYVVPEAGRVLDPAGIVDAVAGRLAAHMVPAAVVVLDALPLTVNGKLDRRALPEPDF 5992 Query: 525 RSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQ 584 + RAP+T E+ILA ++A+VLG+E VGVDDSFF +GGDSI+S+Q+V RA+A+G+ Sbjct: 5993 GRQVSLGRAPATETERILAGLFAEVLGLESVGVDDSFFAVGGDSIMSIQLVTRAKASGVV 6052 Query: 585 CRPRDIFVEQTXXXXXXXXXXXXESHVVDE----GVGPVVATPIMRWLREVDGPTGQFNQ 640 PRD+F +T + ++E GVG TPI+ W+ G +++Q Sbjct: 6053 ITPRDVFERKTVAALAEVATAGEQVVTLEELPGGGVGEFPLTPIVHWMLGRGGDFRRYSQ 6112 Query: 641 TVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR 700 + PA + ED + LQA+LDRH LR R+ + ++ V G V A +R Sbjct: 6113 AALITTPAALDEDALTAALQAVLDRHDMLRARLYRSDRAERGAAMAVAPPGWVRATAVVR 6172 Query: 701 TV-----DALTDDVLVE---ARNRLDPAAGAMVSAVWVRETS------QLVLMIHHLAVD 746 TV D+ T E A +RLDP +G MV AVW ++ +L+++ HH+ VD Sbjct: 6173 TVSLDPADSFTVAASFELDAAADRLDPESGVMVQAVWFASSATPAAPGRLLIVAHHVVVD 6232 Query: 747 GVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVT 806 GVSWRIL+ DL +A AQ +G+ LP GTS RW+ L + A+ + D WR + Sbjct: 6233 GVSWRILVPDLALACAQVLSGEPPSLPGTGTSMRRWAHALTDVAQEPSRTAELDLWRQML 6292 Query: 807 SVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA--- 863 P + T V + + V T LL +P AF V D LL A LA Sbjct: 6293 DTPDPPLGSRALTAADVQTSDVEVRIPVAVTEALLTTLPQAFHGSVGDGLLTALALALVR 6352 Query: 864 WTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGD 923 W + V++EGHGR +++ DL+RTVGWFTT +PV L + + + A Sbjct: 6353 WRRARGIESSGALVNLEGHGREEQVVPGADLARTVGWFTTIFPVGLDLSGVDIDDAFAAG 6412 Query: 924 AALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPE-----VDLGGSDPTIGFNYLGRLGAGA 977 A G VKAVKE+L+S+P+ G+ +GLLRYL+ E L G+ + FNYLGRLG+G+ Sbjct: 6413 PAAGVAVKAVKERLQSIPDHGIGFGLLRYLDAETAPELAALPGAQ--VSFNYLGRLGSGS 6470 Query: 978 GELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDE 1037 + D+ +P V++NA T DT GP+L A+W++ Sbjct: 6471 APDGDWTPVSDEGLAAAAHSG----LPAAAVVDVNARTTDTAAGPALAATWSFPVGVIAA 6526 Query: 1038 EQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYD-VTDVLPLT 1096 + L+ LW +AL + AH R GGGG TPSD+ RL Q ID+L +RY +TDV PL+ Sbjct: 6527 DDVGELASLWADALEALTAHARSGGGGFTPSDLNLVRLGQSAIDDLERRYPAMTDVWPLS 6586 Query: 1097 PVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFV-EQ 1155 P+Q G+LFH+ A D Y VQL + + G +D RLR A ++ RHPNL + F + Sbjct: 6587 PLQAGMLFHAELA-DESVDAYLVQLILDLGGDVDAARLRRAAAALLDRHPNLRSAFCHDA 6645 Query: 1156 FGEPVQVLTADPMIAWRYLDLRG-DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRT 1214 G VQV++ + WR +DL G D+ EIE+L AA+R+ D+ P R L+RT Sbjct: 6646 EGGAVQVVSGRVAVPWREIDLSGLDEDAAAAEIERLLAADRTTPFDMATAPLIRFLLVRT 6705 Query: 1215 SGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPA----AAPYRNFVNWLXXXXXX 1270 +G + R V T HHI++DGWS+P++++E+ Y P+ YR+++ W+ Sbjct: 6706 AGGRCRLVSTNHHILLDGWSMPLMIRELLTLYATDADPSPLARVRDYRDYLLWMSGRDTD 6765 Query: 1271 XXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAE--------TTRALGELARSQHT 1322 W + L G E PTL+ VP R + VS E T L E AR++ Sbjct: 6766 VSARAWADALAGVEEPTLL----VPADRARQLSTVSREWVFDLDEDRTDRLRESARARGL 6821 Query: 1323 TINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADT 1382 T+N++LQ AW +L +TG+ DV FG VSGRP +L+G E+M+GL INTVP+R + + Sbjct: 6822 TLNSILQTAWGIVLAMLTGRDDVVFGATVSGRPPELSGIETMIGLFINTVPVRVTLRPEE 6881 Query: 1383 TVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAF---MGVQ 1439 T+G LL ++Q+ L+H + L +I +G FDTL ++ESYP+D + + Sbjct: 6882 TLGALLERVQAEQAAMLDHHYTGLAEIQDAAGPGVGFDTLTVFESYPVDRAGLSEDTDIA 6941 Query: 1440 ELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMI-- 1497 L VT + R+ HYPLS++A L L+ EY +F IE + +R R+L+A Sbjct: 6942 GLRVTGVDARDAAHYPLSLVASAAASLHLKFEYVPDLFTPGAIEDIAERVVRVLDACTGP 7001 Query: 1498 DDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFE 1557 D P RLS ++ + ER +L V P S +++P++F V DP+A A++ Sbjct: 7002 DVPLARLS---LLTERERAEL-----VPVRGGPAGSVRTLPQIFTDAVAVDPDAVALSSG 7053 Query: 1558 GESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDP 1617 ++Y ELDE +N+LA L G P SVA+ +PRS ++++ + AV +TGA ++P+DP Sbjct: 7054 DVEVSYRELDERSNRLARALIARGLGPETSVAVGIPRSIESVLCVWAVARTGAVFVPVDP 7113 Query: 1618 SVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTP----- 1672 + P R+ ML D++ +TT + R+R ++ + +DDPA + P Sbjct: 7114 NYPGERITHMLTDSECALGLTTSEHRARLPE-NIGWLVLDDPAFAAECAAASAAPVDDGD 7172 Query: 1673 -----SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVF 1727 + D AY++YTSG+TG PKGV +TH + A A PG+ + + F Sbjct: 7173 RTAPVTLDTAAYLVYTSGSTGRPKGVTVTHRGLDNFARDQLARFGADPGSRTLHFSTPSF 7232 Query: 1728 DVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG 1787 D SV+E A +VIVP ++ G D+L L+ V + T +A+ + P GL+ Sbjct: 7233 DGSVFEYLQAFGAAATMVIVPTTVFGG-DELAQLIRDRHVTHAFVTTAALASLDPAGLDH 7291 Query: 1788 -TALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKG 1846 T + V GEACP E+V RWA R + NAYGPTE+T+ + IS PL+PG D + IG P+ Sbjct: 7292 FTDVAVGGEACPPELVSRWAPGRRLYNAYGPTETTVMSNISDPLTPG-DRITIGGPIRGV 7350 Query: 1847 ATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDL 1906 VLD L+PVP GV GELYLA LT RFVA P E G RMYRTGD+ Sbjct: 7351 TELVLDSRLQPVPAGVPGELYLAGAGLARGYHRRPGLTAERFVADP-AEAGQRMYRTGDI 7409 Query: 1907 VRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVG 1966 VRW + ++YLGR+D QVK+RG+RIELGEI L+ V AV +A GD L Sbjct: 7410 VRWTPERTIEYLGRSDFQVKVRGFRIELGEIDTTLTADPDVRFAVTVAYRGPAGDTLLAS 7469 Query: 1967 YITGTADPAAARSELT----NRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ-SA 2021 Y+ + A +T RLP++MVP+++ L+ +PL GK DR+ALPAP + A Sbjct: 7470 YVVPAPEHALDTETITRRLAGRLPSHMVPSSITVLDEIPLNAVGKFDRKALPAPRFDVGA 7529 Query: 2022 QRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSV 2081 + YRAP E+T+A +FA VLG+ R A R A + ALD D+ V Sbjct: 7530 REYRAPADPVEETVAEVFAEVLGLARVSADAGFFDLGGNSLSATRAVARLRAALDTDIGV 7589 Query: 2082 RTLFEAPTVAKLSLHVEH-----------DAGERTDRV 2108 R LFEAPTV + +EH AG R DR+ Sbjct: 7590 RALFEAPTVEAFAARIEHAGAGPSGRPALTAGARPDRI 7627 Score = 516 bits (1330), Expect = e-143 Identities = 379/1096 (34%), Positives = 535/1096 (48%), Gaps = 122/1096 (11%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ QQ + F + F Y + + + +TG LD LR AV V+ RH +L + Sbjct: 1349 IPLSLAQQRMWFINQF--DTSSVAYNIPMAVRLTGPLDADTLRAAVGDVIERHESLRTVY 1406 Query: 1153 VEQFGEPVQVL--TADPMIAWRYLDLRGDDLTP----DHEIEQLCAAERSAVCDLLERPT 1206 P QV+ TAD + DLTP D + + A + D+ + Sbjct: 1407 PASTDGPYQVVVDTADVV----------PDLTPHVDGDESLHERIATLLAGGFDVSAKVP 1456 Query: 1207 FRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRN 1259 RAAL+ T ++H V+ HHI DG SL L +++ Y R P Y + Sbjct: 1457 LRAALLWTGPDEHVLVIVVHHIAADGASLAPLARDLMVAYSSRRSGTPPSWEPLPVQYAD 1516 Query: 1260 FVNWLXXXXXXXXXXX---------WREVLDGFETPTLVAPP---GVPGPRGIE----SY 1303 F W WR VL E P + A P P R +E ++ Sbjct: 1517 FSVWQRRLLGSAEDADSLMSRQLQYWRGVLA--ELPEVSALPLDRNRPPARSLEGATAAF 1574 Query: 1304 RVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAES 1363 + A R L LAR T+ V+ AA LL RM+G DVA GT ++GR A + Sbjct: 1575 AIDAGLHRQLLLLAREHQATLFMVMHAALAVLLSRMSGSGDVAIGTPIAGRGE--AALDD 1632 Query: 1364 MVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQ 1417 +VG+ +NT+ +R V D+L + + H + + + H Sbjct: 1633 LVGMFVNTLVLRTPVEPGEVFTDVLARARDTDLGAFGHTDVPFESVVDELAPGRSTSHSP 1692 Query: 1418 LFDTLFLY---------------ESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALP 1462 LF L + E+ +D +L++ E+++ + ++ L Sbjct: 1693 LFQVLLEFQNTVRAHLELPGLTVEAVDVDPGVAKFDLQLSLAEYHDEKGTAAGMAAAFL- 1751 Query: 1463 GHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQ-LDEW 1521 Y T VFD + +E +RF R+L A++DDPA + + V+ ER LD W Sbjct: 1752 ---------YATDVFDRTSVEGFGERFVRVLRAVVDDPAAVVGDIPVLGAVERDLVLDRW 1802 Query: 1522 ANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYG 1581 V Q++ E+FAR P+A AV E+L YGELDE AN+LA LL G Sbjct: 1803 NREGVTADA----QTVVELFARVAASTPDATAVVCGDETLTYGELDEQANRLARLLIAEG 1858 Query: 1582 AAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGD 1641 VA+MV R+ +V +LAVL G Y+P+D S PA R+ M DA+PV AV + + Sbjct: 1859 VGTESLVAVMVDRTPALVVTLLAVLAAGGGYVPVDTSYPAERVAAMFDDARPVCAVVSAE 1918 Query: 1642 LRSRFDGFDLQVVEVDDPA----------VEIYPSTTLLTPSPDDIAYMIYTSGTTGVPK 1691 S + VV +DDPA + + S L D +AY+I+TSG+TG PK Sbjct: 1919 FASLAPA-GIPVVAIDDPATAGAMAELSGLPVTDSDRLRPLWADAVAYVIFTSGSTGRPK 1977 Query: 1692 GVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESI 1751 GV ++H V +L VW+ +HS FD SVWE+WGAL+HGGRLV+V Sbjct: 1978 GVQVSHRCVVTLLANTRELFGFDSSDVWTLFHSYAFDFSVWELWGALVHGGRLVLVDYFT 2037 Query: 1752 AGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTA-------------LVVAGEACP 1798 A SPD LL E V VL QTP+A ++ A ++ GEA Sbjct: 2038 ARSPDTFLELLRRERVTVLNQTPTAFYQLTEADRAANAVNDAGGSPLSLRHVIFGGEALD 2097 Query: 1799 TEVVDRWAV---DR--VMINAYGPTESTI---YAAISAPLSPGSDVVPIGSPVPKGATFV 1850 ++RW DR V++N YG TE+T+ + A+ L+ IG +P +V Sbjct: 2098 VGQLERWYTRHDDRAPVLVNMYGITETTVHVSFLALDRALAASVPGSVIGGGLPGLRVYV 2157 Query: 1851 LDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFG--EPGARMYRTGDLVR 1908 LD L PVPPGVVGELY++ LT TRFVA PF GARMYR+GD+V+ Sbjct: 2158 LDGRLHPVPPGVVGELYVSGDQVTRGYIGRQGLTSTRFVADPFDHHRAGARMYRSGDVVK 2217 Query: 1909 WGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAR-EDRPGDKRLVGY 1967 WG G+L+Y+GR+D QV++RG+R+ELGE++AAL+ GV Q+VV+ R +DR GD RLVGY Sbjct: 2218 WGAGGRLEYMGRSDFQVQLRGFRVELGEVEAALAACAGVAQSVVVVRGDDRDGD-RLVGY 2276 Query: 1968 I---TGT-ADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQ 2022 + TG D AA + +P+YMVPAAVV ++ LPLTVNGKLDR+ALP ++ S Sbjct: 2277 VVPETGADVDAAAVLDAVGESVPSYMVPAAVVVIDALPLTVNGKLDRKALPEADFGTSTL 2336 Query: 2023 RYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVR 2082 + AP E+ +A +FA +LG+ R A R+ A VN A+ L VR Sbjct: 2337 GFVAPRNPVEEIVAAVFADLLGIVRVGANDSFFALGGNSLTATRLVARVNAAVGNRLGVR 2396 Query: 2083 TLFEAPTVAKLSLHVE 2098 +F+APTVA L+ E Sbjct: 2397 DVFDAPTVAGLAARAE 2412 Score = 503 bits (1295), Expect = e-139 Identities = 373/1080 (34%), Positives = 528/1080 (48%), Gaps = 109/1080 (10%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D +PL+ QQ + F + F Y + + + +TGVLD L AV VVARH +L Sbjct: 5022 DRIPLSLAQQRMWFVNQF--DTSSPAYNIPIALRLTGVLDHAALLAAVGDVVARHESLRT 5079 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 F P QV+ D A LD + D + AA SA D+ + FRA Sbjct: 5080 VFPGSVDGPHQVIV-DAGRATPRLDPVA--VAGDRALRDALAALVSAGFDVSDEIPFRAR 5136 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNFVNW 1263 L QH + HHI DG+S+ L +++ Y + P Y ++ W Sbjct: 5137 LFELEPEQHVLAIVVHHIAADGFSMMPLARDVMLAYTARTVGDTPGWTPLPVQYADYSVW 5196 Query: 1264 LXXXXXXXXXXX---------WREVLDGFETPTLVAPPGVPGPRGIE-SYR-------VS 1306 W + L G +P ++ P V PR ++ SYR V Sbjct: 5197 QRDFLGAVDDPDSVLSRQLGYWTDTLSG--SPEVLQIP-VDRPRPVQRSYRGDVVEFDVP 5253 Query: 1307 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVG 1366 A RAL +A ++T+ + AA+ LL R++G DV GT V+GR A + +VG Sbjct: 5254 ARLHRALNTIAAQHNSTLFMAVHAAFAVLLSRLSGTDDVTMGTPVAGR--GQAVLDDVVG 5311 Query: 1367 LLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQLFD 1420 + +NT+ +R V + G++L +++ EH + + + H LF Sbjct: 5312 MFVNTLVLRTVVDPRASFGEVLTAVRAADLGAFEHADIPFERLVDHLAPERSTSHTPLFQ 5371 Query: 1421 TLFLY---------------ESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHE 1465 L + +S +D EL++ E +R+ A G Sbjct: 5372 VLIEFRNAEGTHLELPGLTVDSLDVDLGVAKFDLELSLAEQIDRD--------GAPAGLA 5423 Query: 1466 LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRA 1525 GLR + T V D + +RF R+LE++ + ++++D ER + Sbjct: 5424 AGLR--FATDVLDRDTVARFGERFLRVLESVAVATELPVGDIEILDTAERDLV-----LP 5476 Query: 1526 VLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPG 1585 +P ++ E+F R +R A AV EG SL Y ELD AN+LA LL GA P Sbjct: 5477 PFAEPPAPDATLAELFERAAQRSRHATAVVCEGVSLTYDELDTRANRLARLLIARGAGPE 5536 Query: 1586 KSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRS- 1644 VA+ RS + +VA+LAV+K+GA Y+P+D + PA RL F+ DA+PV +TT + S Sbjct: 5537 TLVAVAAARSVELVVALLAVVKSGAGYVPVDVTYPAERLAFVFADARPVCVLTT-EAESD 5595 Query: 1645 --RFDGFDLQVVEVDDPAVEIYPSTTLLTPS--------PDDIAYMIYTSGTTGVPKGVA 1694 R G L +V+ + E+ ++ L PD +AY+IYTSG+TG PKGV Sbjct: 5596 AVRASGVPLLLVDSAETVAELDRTSPLPVTDGDRTGPLRPDSVAYVIYTSGSTGQPKGVQ 5655 Query: 1695 ITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGS 1754 + H NV + VW+ +HS FD SVWE+WGALLHGGRLV+V S Sbjct: 5656 VAHRNVVTLFANTQPLFRFDACDVWTMFHSAAFDFSVWELWGALLHGGRLVVVDYFTTRS 5715 Query: 1755 PDDLHALLVSEGVNVLYQTPSAV-------RMMSPEGLEGTALVVAGEACPTEVVDRWAV 1807 PD LL E V VL QTP+A R+ L +V GEA + RW Sbjct: 5716 PDMFLRLLRDENVTVLNQTPTAFYQLAEADRVAGATELSLRVVVFGGEALDLGQLTRWYA 5775 Query: 1808 DRV-----MINAYGPTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVP 1859 V ++N YG TE+T++ + + A L+ + IG +P +VLD L PVP Sbjct: 5776 RHVDTAPALVNMYGITETTVHVSHLPLDAELAASASASVIGRALPGLRVYVLDSRLHPVP 5835 Query: 1860 PGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLG 1919 PGVVGELY++ LT TRFVA P PG+RMYR+GDL RW DGQL+YLG Sbjct: 5836 PGVVGELYVSGPQVSRGYLGRFALTSTRFVADPH-TPGSRMYRSGDLGRWNADGQLEYLG 5894 Query: 1920 RADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTA----DPA 1975 R D QV+++G+RIELGE+++AL +GV Q+VV+AR + RLVGY+ A DPA Sbjct: 5895 RNDFQVQVKGFRIELGEVESALLACEGVAQSVVLARRE-----RLVGYVVPEAGRVLDPA 5949 Query: 1976 AARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKT 2034 + RL A+MVPAAVV L+ LPLTVNGKLDRRALP P++ + RAP TETE+ Sbjct: 5950 GIVDAVAGRLAAHMVPAAVVVLDALPLTVNGKLDRRALPEPDFGRQVSLGRAPATETERI 6009 Query: 2035 LAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 LAG+FA VLG+E ++++ A ++ R +FE TVA L+ Sbjct: 6010 LAGLFAEVLGLESVGVDDSFFAVGGDSIMSIQLVTRAK-ASGVVITPRDVFERKTVAALA 6068 Score = 503 bits (1295), Expect = e-139 Identities = 373/1073 (34%), Positives = 523/1073 (48%), Gaps = 90/1073 (8%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D +PL+ QQ + F + F Y + + + +TG LD L AV VV RH +L Sbjct: 7625 DRIPLSYAQQRMWFINQF--DTSSPAYNIPMVVRLTGDLDVDALTAAVTDVVTRHESLRT 7682 Query: 1151 RFVEQFGEPVQVLTAD--PMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFR 1208 RF + GEPVQ + A PM+A + DD E+ +L A D+ + R Sbjct: 7683 RFPLRDGEPVQEILAPTAPMLAPTAV---ADDSRLREELTRLVTAG----FDVAQAVPLR 7735 Query: 1209 AALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFV 1261 AL H + HHI DG+S+ L++++ Y R P P Y ++ Sbjct: 7736 VALFSLDPTDHVLAVVVHHISADGFSMAPLVRDVMVAYESRVHGRTPGWTPLPVQYADYT 7795 Query: 1262 NWLXXXXXXXXXXX---------WREVLDGF-ETPTLVAPPGVPGPRGIESYRVSAETTR 1311 W W L G E L A P + RV Sbjct: 7796 LWQRRLLGSEDDPGSLISRQLAYWESALAGLPELLELPADRRRPAQQSFRGERVRFAIDP 7855 Query: 1312 ALGE----LARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGL 1367 L E AR +T ++ AA LL R+ G DVA GT ++GR A + +VG+ Sbjct: 7856 GLHERIRTAAREHRSTEFMIVHAALAVLLGRLGGTGDVAIGTPIAGRGE--AALDDLVGM 7913 Query: 1368 LINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG------HEQLFDT 1421 + T+ +R V A DLL +++ H L + G H LF Sbjct: 7914 FVGTLALRTPVEAGQPFRDLLARVRDADLGAFAHADLPFERVVDAVGPVRSTAHSPLFQV 7973 Query: 1422 LFLYESYPIDTSAFMGVQ------ELAVTEFNNREYNHYPLSVM-----ALPGHELGL-- 1468 +++ G+ +LAV + + L V+ A G G+ Sbjct: 7974 SLEFQNTENPALRLPGLTVEGLDPDLAVVKVD--------LEVILDERFAADGSAAGMVG 8025 Query: 1469 RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLT 1528 ++Y T +FD + +RF R+L + +P + ++++ DE L + Sbjct: 8026 AIDYATDLFDADTVRGFAERFVRILGTVTAEPGVPVGDIEILGTDEVAALTPARGAS--- 8082 Query: 1529 QPVDSPQSI-PEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 D+P + PE+ + VERD A AV++ G +++Y ELDEA+N+LA L GA PG + Sbjct: 8083 ---DAPNVLLPELLSAAVERDRGADAVSYRGRTISYRELDEASNRLARRLIEDGAGPGTT 8139 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VAL +PRS ++++++ AV +TGAA+LP+DP P R+E ML D+ V+ VT R + Sbjct: 8140 VALSLPRSIESVLSVWAVARTGAAFLPVDPGYPLDRIEHMLTDSGAVSGVTLRAHRDQLP 8199 Query: 1648 GFDLQVVEVDDPAVEIYPSTTLLTPSP------------DDIAYMIYTSGTTGVPKGVAI 1695 G + + +DD E L +P+P AY+IYTSG+TGVPKGVA+ Sbjct: 8200 G-TVNWIVLDDAEDE--ERIRLQSPAPVTDADRTAPLHEAHPAYLIYTSGSTGVPKGVAV 8256 Query: 1696 THGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSP 1755 TH + + L PGA + S FD SV+E+ A G LVI P +I G Sbjct: 8257 THRGLANLAAEERDRLAVTPGARVLHFASPSFDASVFELVMAFCAGATLVIAPPTIYGGT 8316 Query: 1756 DDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGT-ALVVAGEACPTEVVDRWAVDRVMINA 1814 + L ALL E V+ + TP+A+ M P G E LVVAGEACP E+V RWA R M NA Sbjct: 8317 E-LAALLSDERVSHGFVTPTALASMDPLGFESLRTLVVAGEACPPELVARWAPGRRMFNA 8375 Query: 1815 YGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXX 1874 YGPTE+TI + IS L PG + +G+P + VLD LRPVP GVVGELY++ Sbjct: 8376 YGPTETTIMSNISDALVPGEPIT-LGAPTRGVSEVVLDSRLRPVPLGVVGELYVSGRALA 8434 Query: 1875 XXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIEL 1934 LT +RFVA P+G PG RMYRTGD+VRW DG L+Y+GR+D QVKIRG+RIE Sbjct: 8435 SGYHRRPGLTASRFVAAPWGPPGERMYRTGDVVRWRRDGTLEYVGRSDFQVKIRGFRIEP 8494 Query: 1935 GEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELT----NRLPAYMV 1990 GEI A L+D V AV I R G+ LV Y+ +ELT RLPA+MV Sbjct: 8495 GEIDAVLTDHPDVGFAVTIGRAGPAGEPLLVSYVRPIGGADVDTAELTRLVGERLPAHMV 8554 Query: 1991 PAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXX 2050 PAA+V LE +PLT GKLDR ALPAPE+ S +R P + E + +FA VLG++R Sbjct: 8555 PAAIVVLEQIPLTPVGKLDRTALPAPEFLSGAAFRLPANDLEAAIVDVFAEVLGLDRVGA 8614 Query: 2051 XXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 A +V AA+ L + ++ +F PT A L+ + + E Sbjct: 8615 EDNFFERSGNSLLATKVIAALQERLGRKIPLQWMFLDPTPAGLARRIAVPSAE 8667 Score = 487 bits (1254), Expect = e-135 Identities = 365/1095 (33%), Positives = 522/1095 (47%), Gaps = 94/1095 (8%) Query: 1088 DVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPN 1147 D + +P++ QQ + F + F Y V + + ++G LD L AV VV RH + Sbjct: 2428 DPSREVPVSLAQQRMWFINQF--DTASAAYNVAIALRLSGTLDAQALDAAVADVVERHES 2485 Query: 1148 LAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTF 1207 L F P QV+ +A D E+ +L SA D+ Sbjct: 2486 LRTVFPLTDNGPRQVILPAEKVAPPLTPHAVASADLDAELHRLL----SAGFDVTTEAPV 2541 Query: 1208 RAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXX 1267 RA L + ++H + HH+ DG+S+ L +++ + Y R AAP +W Sbjct: 2542 RARLFGVNEHEHVLAVVVHHVAADGFSMVPLARDVLSAYTA-RCRGAAP-----DWTPLP 2595 Query: 1268 XXXXXXXXWREVLDGFE--------------TPTLVAPPGV---------PGPRGIESYR 1304 W+ G E T TL P V P R + + R Sbjct: 2596 VQYADYTLWQRDWLGDEDDDGSPLARQLDYWTATLADLPDVLELPTDRPRPAARTLGAGR 2655 Query: 1305 VSAETT----RALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAG 1360 V + R++ +LAR +T+ L +A T LL R++ D+A GT ++GR A Sbjct: 2656 VEFDIDPDLHRSVVQLARRHGSTVFMALHSALTVLLSRLSASDDIAVGTPIAGRGE--AE 2713 Query: 1361 AESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSG 1414 + +VG+ +NT+ +R V T +LL Q++ H + + + Sbjct: 2714 LDDLVGMFVNTLVLRTPVDGARTFAELLAQVREADLGAFTHADVPFERVVESLRPSRSTA 2773 Query: 1415 HEQLFDTLFLYES-------------YPIDTSAFMGVQELAVTEFNNREYNHYPLSVMAL 1461 + LF + +++ P+D + +L +T N + + +P + A Sbjct: 2774 YSPLFQVMLEFQNTERPELELPGLHVEPLDLAFDTINFDLQLTLRENVDADGHPAGISAA 2833 Query: 1462 PGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEW 1521 G Y T +FD + +R R+L A+ + P + +DV+ ER L Sbjct: 2834 LG--------YATDIFDADTVTAFAERLVRILSAVTESPDAPVGDVDVLGAGERAALTSA 2885 Query: 1522 ANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYG 1581 + P + +++P++ DP A A+ +G ++Y +LDE +N+LA LL G Sbjct: 2886 SG-----GPGVAARTLPQMLTAAAAADPAAVALVSDGRQVSYRDLDEWSNRLARLLIERG 2940 Query: 1582 AAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGD 1641 P + VAL +PRS ++++A+ +V KTGAA+LP+DP+ PA R+E+MLGD+ VA +TT Sbjct: 2941 VGPEQVVALALPRSIESVLAVWSVAKTGAAFLPVDPNHPAERIEYMLGDSGAVAGLTTAA 3000 Query: 1642 LRSRFDGFDLQVVEVDD---------PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKG 1692 LRS +V D PA + + D AY+IYTSG+TG PKG Sbjct: 3001 LRSALPASIPWLVPGDPETEAELALLPAAAVTDADRTSALHVDHPAYVIYTSGSTGKPKG 3060 Query: 1693 VAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIA 1752 V TH + T + + S FD SV E+ A+ G +VI S+ Sbjct: 3061 VVTTHRGLANFAATEQNTFGTTAASRTLHFASPSFDASVLELMLAIGPGATMVIASPSVY 3120 Query: 1753 GSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVV-AGEACPTEVVDRWAVDRVM 1811 G D+L LL+ E V + TP+A+ + P GLE VV GE CP E+V RWA R M Sbjct: 3121 GG-DELAELLLRERVTHCFVTPAALASVDPAGLESVQCVVTGGETCPPELVARWAPGRAM 3179 Query: 1812 INAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXX 1871 +AYGPTEST+ ++IS PL+PG + V IG+P VLD+ L PVP GV GELYLA Sbjct: 3180 FDAYGPTESTVVSSISTPLAPG-EPVTIGAPTLGFTAAVLDQRLHPVPAGVAGELYLAGP 3238 Query: 1872 XXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYR 1931 LT RFVA PFG PG+RMYRTGDLVRW DGQL YLGR D QVKIRG+R Sbjct: 3239 ALARGYHGRYPLTAERFVANPFGPPGSRMYRTGDLVRWTADGQLDYLGRTDFQVKIRGFR 3298 Query: 1932 IELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTNRLPA 1987 IELGE+++AL V AV R D RL+GY+ DP RL + Sbjct: 3299 IELGEVESALLAHGDVAAAVADVRRDERSGDRLIGYVVPEPGADIDPGEVLQFAGTRLAS 3358 Query: 1988 YMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGIFAHVLGVE 2046 YMVPAAVV + LP+TV+GKLDR+ALP P++ R P TETE LAG+F VLG+ Sbjct: 3359 YMVPAAVVVIAALPVTVHGKLDRKALPEPDFGVVVTDSRPPRTETEALLAGLFRDVLGLG 3418 Query: 2047 RXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTD 2106 ++++ A A LS R +FE TVA L+ V H ER D Sbjct: 3419 SVGMDDSFFALGGDSIMSIQLVARAKAA-GLILSPRDVFERRTVAGLA-EVAH--YERAD 3474 Query: 2107 RVSFAAVHGSDVTEV 2121 V + G+ V V Sbjct: 3475 AVVLEELPGAGVGPV 3489 Score = 439 bits (1128), Expect = e-120 Identities = 330/950 (34%), Positives = 476/950 (50%), Gaps = 99/950 (10%) Query: 24 IEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVL 83 ++ W V D T+ LFA PDA A+V GD + TY ELDE +NRLA +L Sbjct: 1799 LDRWNREGVTADAQ----TVVELFARVAASTPDATAVVCGDETLTYGELDEQANRLARLL 1854 Query: 84 AEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAAL 143 G + VA ++ R+ ++++L+VL G Y+PVD ++P R+ M DA+PV A+ Sbjct: 1855 IAEGVGTESLVAVMVDRTPALVVTLLAVLAAGGGYVPVDTSYPAERVAAMFDDARPVCAV 1914 Query: 144 TTADLRSRLDQYDLAVIDMADPA----------IDRRPSDALSGPRPDDLAYMTYTSGTT 193 +A+ S L + V+ + DPA + SD L D +AY+ +TSG+T Sbjct: 1915 VSAEFAS-LAPAGIPVVAIDDPATAGAMAELSGLPVTDSDRLRPLWADAVAYVIFTSGST 1973 Query: 194 GVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVV 253 G PK V V+H V L++ VW+ +HS FD SVWE+WGAL+HGGRLV+V Sbjct: 1974 GRPKGVQVSHRCVVTLLANTRELFGFDSSDVWTLFHSYAFDFSVWELWGALVHGGRLVLV 2033 Query: 254 PESVGSSPDDLHNLLITEKVSVLCQTPSA----------AGMLSPEG---LESTTLIVAG 300 SPD LL E+V+VL QTP+A A ++ G L +I G Sbjct: 2034 DYFTARSPDTFLELLRRERVTVLNQTPTAFYQLTEADRAANAVNDAGGSPLSLRHVIFGG 2093 Query: 301 EACPTELVDRW-------APGRVMINAYGPTEATIYA---AMSEPLXXXXXXXXXXXXXX 350 EA ++RW AP V++N YG TE T++ A+ L Sbjct: 2094 EALDVGQLERWYTRHDDRAP--VLVNMYGITETTVHVSFLALDRALAASVPGSVIGGGLP 2151 Query: 351 XXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGE--TGERMYR 408 ++VLD L P P GVVGELYV+G V GYIGR LT++RFVA PF G RMYR Sbjct: 2152 GLRVYVLDGRLHPVPPGVVGELYVSGDQVTRGYIGRQGLTSTRFVADPFDHHRAGARMYR 2211 Query: 409 TGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAR-EDRPGD 467 +GD+V+WG+ G+LEY+GR+D QV++RG+R+ELGE++AALA GV Q+VV+ R +DR GD Sbjct: 2212 SGDVVKWGAGGRLEYMGRSDFQVQLRGFRVELGEVEAALAACAGVAQSVVVVRGDDRDGD 2271 Query: 468 KRLVGYI---TGT-ADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPE 523 RLVGY+ TG D A + A+ ES+P+YMVP AVVV+D +PLTVNGKLDR+ALP + Sbjct: 2272 -RLVGYVVPETGADVDAAAVLDAVGESVPSYMVPAAVVVIDALPLTVNGKLDRKALPEAD 2330 Query: 524 YRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-G 582 + ++ + AP P E+I+A V+A +LG+ RVG +DSFF LGG+S+ + ++VAR AA G Sbjct: 2331 FGTSTLGFVAPRNPVEEIVAAVFADLLGIVRVGANDSFFALGGNSLTATRLVARVNAAVG 2390 Query: 583 IQCRPRDIFVEQT---XXXXXXXXXXXXESHVVDEGVGPVVATPI------MRWLREVDG 633 + RD+F T ES P P+ M ++ + D Sbjct: 2391 NRLGVRDVFDAPTVAGLAARAEAGDSRPESRPAPAPRDPSREVPVSLAQQRMWFINQFDT 2450 Query: 634 PTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSL-------- 685 + +N + + + + + +++RH +LR T + L Sbjct: 2451 ASAAYNVAIALRLSGTLDAQALDAAVADVVERHESLRTVFPLTDNGPRQVILPAEKVAPP 2510 Query: 686 LVPEAGAVGAREC-LRTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLA 744 L P A A + L + + DV EA R A + V E L +++HH+A Sbjct: 2511 LTPHAVASADLDAELHRLLSAGFDVTTEAPVR------ARLFGVNEHE-HVLAVVVHHVA 2563 Query: 745 VDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFARWSA--LLAEHAKTDTVRDLA 799 DG S L D+ A+ C G + + LP + W L E + Sbjct: 2564 ADGFSMVPLARDVLSAYTARCRGAAPDWTPLPVQYADYTLWQRDWLGDEDDDGSPLARQL 2623 Query: 800 DAWRA-VTSVPQA--LPPVQP-DTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDI 855 D W A + +P LP +P + AG++ +D + R + V A R G Sbjct: 2624 DYWTATLADLPDVLELPTDRPRPAARTLGAGRVEFDIDPDLHRSV---VQLARRHG--ST 2678 Query: 856 LLVAFGLAWTEFLNR----SDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 + +A A T L+R D +G + G G + +L VG F Sbjct: 2679 VFMALHSALTVLLSRLSASDDIAVGTPIAGRG-------EAELDDLVGMF 2721 Score = 433 bits (1114), Expect = e-118 Identities = 315/864 (36%), Positives = 435/864 (50%), Gaps = 68/864 (7%) Query: 1276 WREVLDGFETPTLVAPPGVPGPRGIESYR------VSAETTRALGELARSQHTTINTVLQ 1329 WR LDG L P P P + V E R + LA + TT TV Sbjct: 510 WRRQLDGLPD-LLPLPTDHPRPARLSQASDRVTVVVPGELHRRVAALADAAGTTGRTVFL 568 Query: 1330 AAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLR 1389 A + LL R+TG D+A GTAV VG + V +R++ +++ + D L Sbjct: 569 TALSILLGRVTGSSDIAVGTAVD------------VGDRTDVVVVRSRYASEVSCRDYLS 616 Query: 1390 QLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSA------FMGVQELAV 1443 ++ + H + + + G + D +DT A + +L V Sbjct: 617 HVRDVATEAAAHTGVPFDRLVRELG-VSVSDAYAPIVQVLLDTRAPGAPGPAVSGLDLCV 675 Query: 1444 TEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARR 1503 T + + P V E G + +FD I +R+ R+L+AM DP Sbjct: 676 TVTEAADESGDPAGVTV----EFG----FAADLFDAHTIRVAAERYLRILDAMAADPEVP 727 Query: 1504 LSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNY 1563 + ++++ DER+ L V +P S +++P++FA DP A A++ +GE L+Y Sbjct: 728 VGDIEILSADERSAL-----TPVRGRPGRSERTLPDLFADAAALDPAATALSRQGEELSY 782 Query: 1564 GELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAAR 1623 ELD + Q+A +L G P VAL +PRS ++ ++ AV KTGAA++P+DP+ PA R Sbjct: 783 RELDRWSTQVARMLIDRGVGPESFVALALPRSFRSVASVWAVAKTGAAFVPVDPNYPADR 842 Query: 1624 LEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVE----------IYPSTTLLTPS 1673 +++ML D+ V +T R R + +DDP + + S + Sbjct: 843 IDYMLADSGVVLGLTEEAARGRLHD-SIPWCVLDDPDFQADCAARSGRPLTDSDRIQPLH 901 Query: 1674 PDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWS----QWHSLVFDV 1729 D+ AY+IYTSG+TG PKGV +TH + LD A+ GA S + + FD Sbjct: 902 LDNAAYLIYTSGSTGRPKGVTVTH----RGLDNFAADQQERFGATRSSRTLHFSTPSFDA 957 Query: 1730 SVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL-EGT 1788 SV+E A G +V+VP S G +L LL SE V + T +A+ + P+ L + Sbjct: 958 SVFEYLQAFGVGATMVVVPPSAYGG-SELADLLRSERVTHGFVTTAALGTIPPDSLGDFL 1016 Query: 1789 ALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGAT 1848 +VV GEACP E+V RWA DR + NAYGPTE+TI A ISAP++PG D + +G P+ Sbjct: 1017 DVVVGGEACPPELVARWAPDRRLHNAYGPTETTIMANISAPMTPG-DPITLGGPIRGAEE 1075 Query: 1849 FVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVR 1908 VLD LRPVP GV GELY+A LT RFVA P+G RMYRTGD+VR Sbjct: 1076 VVLDARLRPVPVGVPGELYIAGAGVARGYHRRPGLTAARFVADPYGR--GRMYRTGDVVR 1133 Query: 1909 WGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYI 1968 W D L+YL R+D QVK+RG+RIELGEI A L V AV I R GD LV Y+ Sbjct: 1134 WRPDHTLEYLRRSDFQVKVRGFRIELGEIDAMLQTHPDVRLAVTIGRPGPSGDTVLVSYV 1193 Query: 1969 TGTADPAAARSEL----TNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS-AQR 2023 +EL NRLPAYMVP+ VV L+ +PL GKLDR ALP P + S A Sbjct: 1194 VPAPGRPIETTELLRQVRNRLPAYMVPSVVVVLDEIPLNPVGKLDRAALPEPRFLSAAAE 1253 Query: 2024 YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRT 2083 ++AP E+++A +F VLGVER A RV A VN AL +D+ VR Sbjct: 1254 FKAPTDPVEESIAEVFTEVLGVERISVDDSFFDLGGNSLVATRVIARVNAALGSDVGVRA 1313 Query: 2084 LFEAPTVAKLSLHVEHDAGERTDR 2107 LFEAPT L+ +V E DR Sbjct: 1314 LFEAPTAELLAAYVRRAGTEFVDR 1337 Score = 424 bits (1090), Expect = e-116 Identities = 262/556 (47%), Positives = 335/556 (60%), Gaps = 29/556 (5%) Query: 41 VTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPR 100 V +P L + V R A A+ R+ +YRELDEASNRLA L E GA PG TVA +PR Sbjct: 8087 VLLPELLSAAVERDRGADAVSYRGRTISYRELDEASNRLARRLIEDGAGPGTTVALSLPR 8146 Query: 101 SGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQY----D 156 S E++LS+ +V +TGAA+LPVDP +P RI M++D+ V+ +T LR+ DQ + Sbjct: 8147 SIESVLSVWAVARTGAAFLPVDPGYPLDRIEHMLTDSGAVSGVT---LRAHRDQLPGTVN 8203 Query: 157 LAVIDMAD-----------PAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHN 205 V+D A+ P D + L P AY+ YTSG+TGVPK VAVTH Sbjct: 8204 WIVLDDAEDEERIRLQSPAPVTDADRTAPLHEAHP---AYLIYTSGSTGVPKGVAVTHRG 8260 Query: 206 VTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLH 265 + L + L PG + S FD SV+E+ A G LV+ P ++ + L Sbjct: 8261 LANLAAEERDRLAVTPGARVLHFASPSFDASVFELVMAFCAGATLVIAPPTIYGGTE-LA 8319 Query: 266 NLLITEKVSVLCQTPSAAGMLSPEGLEST-TLIVAGEACPTELVDRWAPGRVMINAYGPT 324 LL E+VS TP+A + P G ES TL+VAGEACP ELV RWAPGR M NAYGPT Sbjct: 8320 ALLSDERVSHGFVTPTALASMDPLGFESLRTLVVAGEACPPELVARWAPGRRMFNAYGPT 8379 Query: 325 EATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYI 384 E TI + +S+ L + VLD LRP P GVVGELYV+G +A+GY Sbjct: 8380 ETTIMSNISDALVPGEPITLGAPTRGVSEV-VLDSRLRPVPLGVVGELYVSGRALASGYH 8438 Query: 385 GRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQ 444 RP LTASRFVA P+G GERMYRTGD+VRW DG LEY+GR+D QVKIRG+RIE GEI Sbjct: 8439 RRPGLTASRFVAAPWGPPGERMYRTGDVVRWRRDGTLEYVGRSDFQVKIRGFRIEPGEID 8498 Query: 445 AALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAV 500 A L V AV I R G+ LV Y+ D A+L + E LPA+MVP A+ Sbjct: 8499 AVLTDHPDVGFAVTIGRAGPAGEPLLVSYVRPIGGADVDTAELTRLVGERLPAHMVPAAI 8558 Query: 501 VVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDS 560 VVL+ IPLT GKLDR ALPAPE+ S A +R P+ E + DV+A+VLG++RVG +D+ Sbjct: 8559 VVLEQIPLTPVGKLDRTALPAPEFLSGA-AFRLPANDLEAAIVDVFAEVLGLDRVGAEDN 8617 Query: 561 FFDLGGDSILSMQVVA 576 FF+ G+S+L+ +V+A Sbjct: 8618 FFERSGNSLLATKVIA 8633 Score = 423 bits (1087), Expect = e-115 Identities = 330/951 (34%), Positives = 467/951 (49%), Gaps = 67/951 (7%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 M A+P + ++L DE + R PG + T+P LFA+ P A AL Sbjct: 720 MAADPEV-PVGDIEILSADERSALTPVRGR-----PGRSERTLPDLFADAAALDPAATAL 773 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 +YRELD S ++A +L + G P + VA +PRS ++ S+ +V KTGAA++P Sbjct: 774 SRQGEELSYRELDRWSTQVARMLIDRGVGPESFVALALPRSFRSVASVWAVAKTGAAFVP 833 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRL-DQYDLAVIDMADPAID-----RRP--- 171 VDP +P RI +M++D+ V LT R RL D V+D D D RP Sbjct: 834 VDPNYPADRIDYMLADSGVVLGLTEEAARGRLHDSIPWCVLDDPDFQADCAARSGRPLTD 893 Query: 172 SDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSL 231 SD + D+ AY+ YTSG+TG PK V VTH + + + + + Sbjct: 894 SDRIQPLHLDNAAYLIYTSGSTGRPKGVTVTHRGLDNFAADQQERFGATRSSRTLHFSTP 953 Query: 232 VFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGL 291 FD SV+E A G +VVVP S +L +LL +E+V+ T +A G + P+ L Sbjct: 954 SFDASVFEYLQAFGVGATMVVVPPSAYGG-SELADLLRSERVTHGFVTTAALGTIPPDSL 1012 Query: 292 -ESTTLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXX 350 + ++V GEACP ELV RWAP R + NAYGPTE TI A +S P+ Sbjct: 1013 GDFLDVVVGGEACPPELVARWAPDRRLHNAYGPTETTIMANISAPMTPGDPITLGGPIRG 1072 Query: 351 XXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTG 410 + VLD LRP P GV GELY+AG GVA GY RP LTA+RFVA P+G RMYRTG Sbjct: 1073 AEEV-VLDARLRPVPVGVPGELYIAGAGVARGYHRRPGLTAARFVADPYGRG--RMYRTG 1129 Query: 411 DLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRL 470 D+VRW D LEYL R+D QVK+RG+RIELGEI A L V AV I R GD L Sbjct: 1130 DVVRWRPDHTLEYLRRSDFQVKVRGFRIELGEIDAMLQTHPDVRLAVTIGRPGPSGDTVL 1189 Query: 471 VGYITGTA----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRS 526 V Y+ + +L + LPAYMVP+ VVVLD IPL GKLDR ALP P + S Sbjct: 1190 VSYVVPAPGRPIETTELLRQVRNRLPAYMVPSVVVVLDEIPLNPVGKLDRAALPEPRFLS 1249 Query: 527 AANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQC 585 AA +++AP+ P E+ +A+V+ +VLGVER+ VDDSFFDLGG+S+++ +V+AR AA G Sbjct: 1250 AAAEFKAPTDPVEESIAEVFTEVLGVERISVDDSFFDLGGNSLVATRVIARVNAALGSDV 1309 Query: 586 RPRDIFVEQTXXXXXXXXXXXXESHV---------VDEGVGPVVATPIMRWLREVDGPTG 636 R +F T V E + +A M ++ + D + Sbjct: 1310 GVRALFEAPTAELLAAYVRRAGTEFVDRPPLVVGERPERIPLSLAQQRMWFINQFDTSSV 1369 Query: 637 QFNQTVITQAPAGVTEDDVVVILQALLDRHATLR----LRVEDTQEDTDEWSLLVPEA-- 690 +N + + + D + + +++RH +LR + + + + +VP+ Sbjct: 1370 AYNIPMAVRLTGPLDADTLRAAVGDVIERHESLRTVYPASTDGPYQVVVDTADVVPDLTP 1429 Query: 691 ---GAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWV-RETSQLVLMIHHLAVD 746 G E + T+ A DV + R + +W + LV+++HH+A D Sbjct: 1430 HVDGDESLHERIATLLAGGFDVSAKVPLR--------AALLWTGPDEHVLVIVVHHIAAD 1481 Query: 747 GVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFARWSALL---AEHAKTDTVRDLAD 800 G S L DL +A++ +G LP F+ W L AE A + R L Sbjct: 1482 GASLAPLARDLMVAYSSRRSGTPPSWEPLPVQYADFSVWQRRLLGSAEDADSLMSRQL-Q 1540 Query: 801 AWRAV-TSVPQ--ALPPVQPDTDTYVTAGQLSA-SLDVETTRQLLGEVPAAFRAGVQDIL 856 WR V +P+ ALP + G +A ++D RQLL + +A + ++ Sbjct: 1541 YWRGVLAELPEVSALPLDRNRPPARSLEGATAAFAIDAGLHRQLL-LLAREHQATLFMVM 1599 Query: 857 LVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPV 907 A + + D IG + G G E A D + V + PV Sbjct: 1600 HAALAVLLSRMSGSGDVAIGTPIAGRG---EAALDDLVGMFVNTLVLRTPV 1647 Score = 58.9 bits (141), Expect = 1e-05 Identities = 77/342 (22%), Positives = 130/342 (38%), Gaps = 29/342 (8%) Query: 1088 DVTDVLPLTPVQQGLLFHSTFARGIGDDV-YAVQLDITITGVLDQHRLRDAVHTVVARHP 1146 D + +PL+ Q+ + FA+ + V ++ + GVLD LR Sbjct: 66 DGGEPIPLSAAQRA----TWFAQQLEPQVPISIAQYVEFHGVLDIDLLRQETVEAAREFE 121 Query: 1147 NLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVC--DLLER 1204 + + + G P+Q + + Y+D R D+ D ER V DL Sbjct: 122 SPFLKVYDVDGRPLQYVDHRTDTSIAYVDFRADE---DPVAAAHAWMERDYVTPLDLSAD 178 Query: 1205 PTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFV--- 1261 ++++T+ + HH+ +DG+ +L+ I A + ++ P N Sbjct: 179 RLVETSILQTADTHFLWYSRIHHVALDGYGAMTMLRRI-AHRYSAKVAGREPDPNRAVSL 237 Query: 1262 --------NWLXXXXXXXXXXXWREVLDGFETPTLVAPPG-VPGPRGIESYRVSAETTRA 1312 + W + G E TL G V +ES +S + Sbjct: 238 RQLYDIDSRYRASERFVTDREYWAGRVAGLEGTTLARTAGQVSATSTVESAVLSDDVVAV 297 Query: 1313 LGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTV 1372 L S+ + + AA L R TG+ DV VS R A + G+L+N Sbjct: 298 LD----SRDSLSAATIIAAAACYLSRRTGRTDVLVTIPVSARTT--AVLRNSGGMLVNVA 351 Query: 1373 PIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG 1414 P+ V AD TV +L+ ++Q L H+ +L+DI +G Sbjct: 352 PMPVSVRADDTVAELIEKVQRELVAALRHQRCSLDDIRRDAG 393 >tr|Q9Z4X6|Q9Z4X6_STRCO Tax_Id=1902 (cdaPSI)SubName: Full=CDA peptide synthetase I;[Streptomyces coelicolor] Length = 7463 Score = 1342 bits (3472), Expect = 0.0 Identities = 880/2191 (40%), Positives = 1179/2191 (53%), Gaps = 155/2191 (7%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVT-IPALFAEQVVR------ 53 + A+PS R + D+L E ++ VLT+ TP + FA+ V R Sbjct: 2717 LVADPSRR-IGDVDVLGPRERER--------VLTEWNDTPRRPVQGTFADHVARHAAERP 2767 Query: 54 ---APDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILS 110 A + + + TY EL+E +NRLA L GA P VA +PRS + +LS L+ Sbjct: 2768 GHLAVETAGAAAPGGALTYGELNERANRLARALLARGAGPERFVAVALPRSADLVLSALA 2827 Query: 111 VLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRL----------DQYDLAVI 160 K GAAYLPVDPAHP RI ++SDA P +TT+ L + L D + A Sbjct: 2828 AFKAGAAYLPVDPAHPAERITHLVSDAAPTLIVTTSALAASLPDTGTPVLLLDTPETAAT 2887 Query: 161 DMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSG 220 A P D +D RP+ AYM YTSGTTG PK V VTH + L+ D +G Sbjct: 2888 LAALPGHDVTDADRPVPLRPEHPAYMIYTSGTTGRPKGVVVTHTGLPGLLDIFTRDCAAG 2947 Query: 221 PGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTP 280 PG Q S FD S WE+ LL G LVV P P+ L L + L T Sbjct: 2948 PGSRILQHLSPSFDASFWELAMGLLTGATLVVAPPETTPGPE-LAELATRHAATHLSLTT 3006 Query: 281 SAAGMLSPEGL-ESTTLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXX 339 S G+L P+ L + TL+V EA P ELV+RW+PGR M+N+YGPTE T+ + MS PL Sbjct: 3007 SVLGLLPPDSLPDGLTLVVGAEAIPPELVERWSPGRTMLNSYGPTETTVCSTMSGPLSGP 3066 Query: 340 XXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPF 399 ++VLD LRP P GV GELY AG +A GY R LTA RFVA PF Sbjct: 3067 AVPPIGSPVANSA-VYVLDAALRPVPPGVPGELYAAGAHLARGYHDRRALTAERFVANPF 3125 Query: 400 GETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVI 459 GE G R+YRTGDLVRW DGQLEYLGRAD QVKIRG RIE EI+A + + + +A VI Sbjct: 3126 GEPGSRLYRTGDLVRWRPDGQLEYLGRADTQVKIRGLRIEPTEIEAVITERPHLARAAVI 3185 Query: 460 AREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLD 515 REDRPGD+RLV Y+ T D A+LR AL E+LP +M+PTA VVLD +PLT+NGKLD Sbjct: 3186 VREDRPGDRRLVAYVVPEPGATVDTAELRAALRETLPDHMIPTAFVVLDALPLTLNGKLD 3245 Query: 516 RRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVV 575 R+ALPAP+Y SA RA P E++L ++ ++LGVE GVDD FFDLGGDSILS+Q+V Sbjct: 3246 RKALPAPDY-SARTSGRAARDPRERLLTALFGEILGVEPAGVDDGFFDLGGDSILSIQLV 3304 Query: 576 ARARAAGIQCRPRDIFVEQT--XXXXXXXXXXXXESHVVDEGV---GPVVATPIMRWLRE 630 ARARAAG+ RD+F QT + D V GP TP+M W Sbjct: 3305 ARARAAGLVLSVRDVFEHQTPALLARSAAAAPAGDRTARDSDVPADGPAPRTPMMGWFAA 3364 Query: 631 VDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEA 690 + FNQ+++ + PA + D + L+A+LDRH LR+RV D+W++ +P Sbjct: 3365 LGSDLAAFNQSLVLRVPAALDPDTLDTALRAVLDRHDALRMRV------ADDWTIEIPPP 3418 Query: 691 GAVGARECLRTVDAL-TDDVLVE---------ARNRLDPAAGAMVSAVWVRETSQ----L 736 G+V +CL DA+ D+ V AR+RL PA G M+ AVW+ + L Sbjct: 3419 GSVTPADCLVRFDAVGLDEAAVRSAVTEQARTARDRLAPADGRMLQAVWLDRGADRDGLL 3478 Query: 737 VLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVR 796 +L+ +HL VDGV+WRIL+ DL A+A G++ L GT + W+ L++ A Sbjct: 3479 LLVANHLVVDGVTWRILVPDLAAAYA----GET--LAPVGTPWRHWALSLSDLAGQPRTE 3532 Query: 797 DLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDIL 856 + D W +V + P DT+ TAG+++A LD +TT LL VP A V D+ Sbjct: 3533 EELDHWHSVLGDTPHTLRLDPARDTHATAGEITAELDADTTEALLTWVPGVCHATVNDVF 3592 Query: 857 LVAFGLA---WTEFLNR-SDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVE 912 L F LA W +D P+ +D+E HGR++E V+LSRT GWFT+ YPV L Sbjct: 3593 LSTFALAVAGWRRGRGEDADAPVVLDLESHGRHEEAVPGVELSRTAGWFTSMYPVRLAP- 3651 Query: 913 NLPWEQVVAGDAALGGIVKAVKEQLRSLP-EGLTYGLLRYLNPEVDLGGSD---PTIGFN 968 +GD + +KAVKEQLR++P +GL YGLLR+LNP + P GFN Sbjct: 3652 ----PAGASGDGSALRALKAVKEQLRTVPGDGLGYGLLRHLNPRTRAALAALPLPEFGFN 3707 Query: 969 YLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASW 1028 YLGR+G + E W I+ MPL H V++NA +T +G LRA W Sbjct: 3708 YLGRIGQEGTD--EAPWTIEGGDVAGIDG----AMPLAHPVDVNAVARETADGTRLRARW 3761 Query: 1029 TWAPSAFDEEQATRLSRLWFEALAGICAHVR-GGGGGLTPSDVAPARLTQRQIDELSQRY 1087 T++ +A + E RL+ WF L + R G GGLTPSD+A L Q +I++L Sbjct: 3762 TYSRTALEPEDTQRLADTWFRLLRRLVEEARQPGAGGLTPSDIAHPALAQDEIEDLEHTV 3821 Query: 1088 -DVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHP 1146 + D+LPL P+Q+G LF + + DVY QL + G D R+R A ++ RH Sbjct: 3822 PGLQDILPLAPLQEGFLFLNLYDEN-ARDVYVGQLAFDLEGSFDGTRMRAAAGALLRRHA 3880 Query: 1147 NLAARFVE-QFGEPVQVLTADPMIAWRYLDL--RGDDLTPDHEIEQLCAAERSAVCDLLE 1203 NL A F + G VQV+ A+ WR DL R D+ D E +L A +R DL Sbjct: 3881 NLRAGFRQTATGTWVQVVPAELEPDWRECDLTDRADEAERDAEAGRLAAGDRERRFDLTS 3940 Query: 1204 RPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH----RLPAAAPYRN 1259 P R IR S ++ R V+T HHI++DGWS+P+L QE+ Y LP PYR+ Sbjct: 3941 PPLMRFTAIRLSADRVRLVMTNHHILLDGWSMPLLWQELTELYVSGGDPVSLPPVRPYRD 4000 Query: 1260 FVNWLXXXXXXXXXXXWREVLDGFETPTLVAP---PGVPGPRGIESYRVSAETTRALGEL 1316 + WL WR L G + TL+AP P P GI + + + T AL Sbjct: 4001 HLAWLGARDRDAARDAWRRSLSGLDEATLLAPDAGPAEAAPLGI-PFGLDRDATAALSAW 4059 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA 1376 AR + T+NTV+Q AW L + TG+ DV FG VSGRP +L G ESM+GL INT+P+RA Sbjct: 4060 ARGRGVTMNTVVQGAWALALAQATGRDDVVFGATVSGRPPELPGVESMIGLFINTLPVRA 4119 Query: 1377 KVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPI--DTSA 1434 ++ +GDL R+LQ+ L+H+ L DI H +GH +LFDT ++++YP+ DT++ Sbjct: 4120 RLDQAEPLGDLFRRLQNEQARLLDHQWPGLADIQHWAGHGELFDTAMVFQNYPVSADTTS 4179 Query: 1435 FMGVQELAVTEFNNREYNHYPLSVMALPGHE-LGLRVEYDTSVFDVSEIETLIDRFQRLL 1493 + L V ++ E + ++++A + L LR++Y + +L DR R+L Sbjct: 4180 -RQLDGLRVAGYDAVESTDFAVNLVAHTRDDALRLRLDYRADACAGDLVRSLADRMLRVL 4238 Query: 1494 EAMIDDPARRLSSMDVVDDDERTQ-LDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAP 1552 EA++ D R ++ +D +D R + L EW TQ +P + E+ + Q P+A Sbjct: 4239 EALVTDSDRPVAHLDTLDPAVRERVLVEW--NGAPTQLPGTP--LHELISEQARLTPDAV 4294 Query: 1553 AVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAY 1612 AV +G SL Y ELD ANQLA L G VA+ + +S DA++++LAVLKTGAAY Sbjct: 4295 AVVCDGTSLTYAELDGGANQLARHLLGEGLGAEDFVAIALAKSLDAVISMLAVLKTGAAY 4354 Query: 1613 LPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTP 1672 LPIDP PA R+ +ML DA+P +T R+ G + V ++ +P Sbjct: 4355 LPIDPDYPAERITYMLDDARPALTLTEPVPVERYTGHSVTAVTDEERR----------SP 4404 Query: 1673 -SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHS-LVFDVS 1730 S AYMIYTSG+TG PKGV I H + L A G + HS L FD++ Sbjct: 4405 WSARHAAYMIYTSGSTGRPKGVVIEHHALATYLHRARNTYTAMTGV--TVLHSPLAFDLT 4462 Query: 1731 VWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS--PEGLEGT 1788 + +W L GG + + + + L + TPS + +++ PE + Sbjct: 4463 ITALWTPLTSGGTVHLTSLEESDTQPSL-----------IKATPSHLPLLTTLPETASPS 4511 Query: 1789 -ALVVAGEACPTEVVDRWAVDR---VMINAYGPTESTI-----YAAISAPLSPGSDVVPI 1839 L++ GEA T+ + W +INAYGPTEST+ + P P VPI Sbjct: 4512 HTLILGGEALHTDHLVTWRTQHPGVQIINAYGPTESTVNITDHHVGEDTPDGP----VPI 4567 Query: 1840 GSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGE-PGA 1898 G P +VLD LRPV PGV GELYLA LT RF A P PGA Sbjct: 4568 GRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSSTPGA 4627 Query: 1899 RMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDR 1958 RMYRTGDL W G L Y GRAD Q+K+RG+RIE GEI+A L+ G+ QA V RED+ Sbjct: 4628 RMYRTGDLAHWNHHGHLTYDGRADHQIKLRGHRIEPGEIEATLTAQTGITQATVQLREDQ 4687 Query: 1959 PGDKRLVGYI----TGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALP 2014 PGD+RLV Y+ + D R LT+ LP YMVP+A+VTL+ LPLT NGKLDR ALP Sbjct: 4688 PGDQRLVAYLVVNDSTEYDEKTVRDALTSALPDYMVPSALVTLDALPLTPNGKLDRTALP 4747 Query: 2015 APEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTA 2074 AP Y ++ RAP T E+ L +FA VLGV+ A R+ + TA Sbjct: 4748 APAYSASTAGRAPRTPREEVLCTLFAEVLGVDLVTIDDNFFDLGGHSLLATRLVSRTRTA 4807 Query: 2075 LDADLSVRTLFEAPTVAKLSLHVEHDAGERT 2105 L +LS+R LFE PTVA L+ ++ RT Sbjct: 4808 LGVELSIRQLFETPTVAGLAEALDASGTVRT 4838 Score = 642 bits (1655), Expect = 0.0 Identities = 436/1135 (38%), Positives = 584/1135 (51%), Gaps = 104/1135 (9%) Query: 30 RAVLTDPGPTPV------TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVL 83 R L D G P+ T+P LFAEQ +R P A ALV G + +Y ELD +NRLA +L Sbjct: 6338 RRSLLDRGTGPLLEGLDATLPELFAEQALRTPGAPALVRGGTTVSYAELDLRTNRLARLL 6397 Query: 84 AEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAAL 143 + G +PG V L+ RS +++ L++ K G AY+P+ +P R+ +++D L Sbjct: 6398 RQQGVRPGTPVVMLMERSPAHVVATLAIAKAGGAYVPLHDTYPLDRMRHVVADTAATLIL 6457 Query: 144 TTADLRSRLDQYD--LAVIDMADPAIDRRPSDALSGP---------------------RP 180 T +R Q + V+D A +DA G RP Sbjct: 6458 TDRAEAARAGQLGARVMVVDEFGAAPSGSEADAAPGTGTGTGTGSRSGYVDDAPEVGLRP 6517 Query: 181 DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEI 240 DLAY+ YTSG+TGVPK VAVTH V LV H P +V FDVS +E+ Sbjct: 6518 QDLAYVMYTSGSTGVPKGVAVTHRGVVDLVRD-HCWRPGVHERVLLHAPH-AFDVSCYEM 6575 Query: 241 WGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTT----L 296 W L+ GG +VV P P + +L+ ++ + T +++ E E + Sbjct: 6576 WVPLVSGGTVVVAPPG-HLDPAAITDLITAHDITAIHLTAGFFRVVAEEAPECFAGVREV 6634 Query: 297 IVAGEACPTELVDRWA---PGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXX 353 + G+ V R P V+ + YGPTE T+ E Sbjct: 6635 LTGGDVVSPAAVARVLAHHPRIVLRHLYGPTETTLCVTQHEVTAPYEARGSLPVGRATGN 6694 Query: 354 L--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGD 411 +VLD++L+P P GV GEL+++G G+A GY+ RPDLT RFVA P+G +GERMYRTGD Sbjct: 6695 TRAYVLDRYLQPVPAGVPGELFISGSGLARGYLDRPDLTCERFVADPYGGSGERMYRTGD 6754 Query: 412 LVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLV 471 LVR+ + G+LEYL RAD+QVKIRG+R+ELGEI+A LA + QA V+ REDRPGD+RLV Sbjct: 6755 LVRYNAAGELEYLARADDQVKIRGFRVELGEIEAVLATRPELAQAAVVVREDRPGDRRLV 6814 Query: 472 GYIT------GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 GY+ G DP LR ++LP YMVP+A VVL T+PLT NGKLDR+ALPAP+Y Sbjct: 6815 GYVVAAAGRDGEVDPDALRAFSRQALPDYMVPSAFVVLGTLPLTANGKLDRKALPAPDY- 6873 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQC 585 AA+ RA TPAE++L ++AQVLG+ VGVDD FFDLGGDSILS+Q+V+RARAAG+ Sbjct: 6874 GAASTGRAARTPAEELLCTLFAQVLGLSAVGVDDGFFDLGGDSILSIQLVSRARAAGLAL 6933 Query: 586 RPRDIFVEQTXXXXXXXXXXXXESHVVDEG-----VGPVVATPIMRWLREVDGPTGQFNQ 640 RD+F Q+ ++ V E GP TP+M + E+ FNQ Sbjct: 6934 AVRDVFEHQSTARLAAALTDRDDAASVPEAEAVPPYGPAPLTPVMARIAELGLGGDDFNQ 6993 Query: 641 TVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR 700 +V+ P V D +V LQ +LD H LRLRV + S V G+V A + L Sbjct: 6994 SVVVSLPPAVDRDRLVPALQRVLDHHDALRLRV------LPDGSTEVRAPGSVPAADVLS 7047 Query: 701 TV-----------DALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ-------------L 736 V DAL + AR+RL PA G M+ AV V T L Sbjct: 7048 VVTRAPGATGEARDALLVEAACAARDRLAPAEGRMLQAVLVDGTDDTDGTGGTSGADGVL 7107 Query: 737 VLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVR 796 +L+ HHL VD V+W I++ DL A+ + E GTS+ +W+ LA A V Sbjct: 7108 ILVAHHLVVDSVTWSIVVPDLAAAY------RGEEPAPVGTSWRQWATSLARLATDPRVE 7161 Query: 797 DLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDIL 856 W + L + D AG++S L TT LL +P A V D+L Sbjct: 7162 AETAHWEHTLTGAGTL-RLDRGRDLQGDAGRISLDLAPHTTEALLTRLPGGVNASVHDVL 7220 Query: 857 LVAFGLA---WTEFLNRS-DTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVE 912 L AF A W D P+ +D+E HGR++E +LSRT GWFT +PV L + Sbjct: 7221 LTAFAFAVAGWRRGRGEDPDAPVVLDLESHGRHEEAVPGAELSRTAGWFTALHPVRLAPD 7280 Query: 913 NLPWEQVVAGDAALGGIVKAVKEQLRSLP-EGLTYGLLRYLNPEVD---LGGSDPTIGFN 968 W ++ AL +K VKEQLRS+P +GL +GLLR+LNP +P GFN Sbjct: 7281 VTDWARLHQDGDALRDGLKQVKEQLRSVPGDGLGHGLLRHLNPTAGPRLARLPEPDFGFN 7340 Query: 969 YLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASW 1028 YLGR A + E W + P+ H VEL+A + +GP LRA W Sbjct: 7341 YLGRRVTPATG-TPEPWTV----TGGGLAASRPTAPMAHAVELSAVVHEGADGPRLRAEW 7395 Query: 1029 TWAPSAFDEEQATRLSRLWFEALAGICAHV-RGGGGGLTPSDVAPARLTQRQIDE 1082 T+A + A RL+ WF AL + R G GGLTPSDV L+Q +I+E Sbjct: 7396 TYARRLVPDHDARRLAEQWFRALEALVEQADRAGTGGLTPSDVTLGSLSQSEIEE 7450 Score = 546 bits (1407), Expect = e-152 Identities = 397/1093 (36%), Positives = 528/1093 (48%), Gaps = 98/1093 (8%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+ QQ L F Y + + +TG LD LR A VV RH +L F Sbjct: 2287 LPLSYAQQRLWFLHQLEGP--SPTYNITGALRLTGDLDPGALRAAFQDVVTRHESLRTVF 2344 Query: 1153 VEQ-FGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAAL 1211 E G VL A A +L D++ D +L A R DL RA L Sbjct: 2345 SEDGHGARQTVLDA----AGVRFELPVADVSEDRLDARLEEAARHCF-DLTTDIPVRAEL 2399 Query: 1212 IRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNWL 1264 R +H +L HHI DGWSL L++++ A Y R P AP Y +F W Sbjct: 2400 FRLGAREHVLLLMVHHIAGDGWSLGPLIRDLAAAYTARAARRAPDWAPLPVQYADFALWQ 2459 Query: 1265 XXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETT 1310 W+E L G E P P V RG V A Sbjct: 2460 RAALGDAADATSPAGRQLAHWKEALAGLPDRLELPADRPLPAVASHRGGRVPLTVPAPLH 2519 Query: 1311 RALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLIN 1370 + ELAR T++ VLQAA LL RM DV GT V+GR D + +VG +N Sbjct: 2520 SGVAELARESRTSVFMVLQAALAALLTRMGAGEDVPLGTPVAGRGDD--AVDQVVGFFVN 2577 Query: 1371 TVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG------HEQLFDTLFL 1424 T+ +R + T LL +++ +H+ L + V H LF L Sbjct: 2578 TLVLRTDTGGNPTFRALLDRVRDTDLTAYDHQDLPFEHLVDVLSPTRSLSHNPLFQVLLS 2637 Query: 1425 YESYPIDTSAFMGVQELAVTEFN----------------NREYNHYPLSVMALPGHELGL 1468 ++ D A + L V N +R+ + P ++ Sbjct: 2638 LDTTQQDALAALSATGLGVRLLNVTTGVAKLDLALEIAEHRDADGAPAGLVGA------- 2690 Query: 1469 RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLT 1528 EY +FD + L++RF RLL+A++ DP+RR+ +DV+ ER + VLT Sbjct: 2691 -AEYSADLFDEGTVTLLVERFLRLLDALVADPSRRIGDVDVLGPRERER--------VLT 2741 Query: 1529 QPVDSPQS-IPEVFARQVERDP---------EAPAVTFEGESLNYGELDEAANQLANLLA 1578 + D+P+ + FA V R E G +L YGEL+E AN+LA L Sbjct: 2742 EWNDTPRRPVQGTFADHVARHAAERPGHLAVETAGAAAPGGALTYGELNERANRLARALL 2801 Query: 1579 VYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVT 1638 GA P + VA+ +PRSAD +++ LA K GAAYLP+DP+ PA R+ ++ DA P VT Sbjct: 2802 ARGAGPERFVAVALPRSADLVLSALAAFKAGAAYLPVDPAHPAERITHLVSDAAPTLIVT 2861 Query: 1639 TGDLRSRFDGFDLQVVEVDDPAV----------EIYPSTTLLTPSPDDIAYMIYTSGTTG 1688 T L + V+ +D P ++ + + P+ AYMIYTSGTTG Sbjct: 2862 TSALAASLPDTGTPVLLLDTPETAATLAALPGHDVTDADRPVPLRPEHPAYMIYTSGTTG 2921 Query: 1689 VPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVP 1748 PKGV +TH + +LD + AGPG+ Q S FD S WE+ LL G LV+ P Sbjct: 2922 RPKGVVVTHTGLPGLLDIFTRDCAAGPGSRILQHLSPSFDASFWELAMGLLTGATLVVAP 2981 Query: 1749 ESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL-EGTALVVAGEACPTEVVDRWAV 1807 P+ L L L T S + ++ P+ L +G LVV EA P E+V+RW+ Sbjct: 2982 PETTPGPE-LAELATRHAATHLSLTTSVLGLLPPDSLPDGLTLVVGAEAIPPELVERWSP 3040 Query: 1808 DRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELY 1867 R M+N+YGPTE+T+ + +S PLS G V PIGSPV A +VLD LRPVPPGV GELY Sbjct: 3041 GRTMLNSYGPTETTVCSTMSGPLS-GPAVPPIGSPVANSAVYVLDAALRPVPPGVPGELY 3099 Query: 1868 LAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKI 1927 A LT RFVA PFGEPG+R+YRTGDLVRW DGQL+YLGRAD QVKI Sbjct: 3100 AAGAHLARGYHDRRALTAERFVANPFGEPGSRLYRTGDLVRWRPDGQLEYLGRADTQVKI 3159 Query: 1928 RGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTN 1983 RG RIE EI+A +++ + +A VI REDRPGD+RLV Y+ T D A R+ L Sbjct: 3160 RGLRIEPTEIEAVITERPHLARAAVIVREDRPGDRRLVAYVVPEPGATVDTAELRAALRE 3219 Query: 1984 RLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVL 2043 LP +M+P A V L+ LPLT+NGKLDR+ALPAP+Y + RA E+ L +F +L Sbjct: 3220 TLPDHMIPTAFVVLDALPLTLNGKLDRKALPAPDYSARTSGRAARDPRERLLTALFGEIL 3279 Query: 2044 GVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLH-VEHDAG 2102 GVE ++++ A A LSVR +FE T A L+ AG Sbjct: 3280 GVEPAGVDDGFFDLGGDSILSIQLVARARAA-GLVLSVRDVFEHQTPALLARSAAAAPAG 3338 Query: 2103 ERTDRVSFAAVHG 2115 +RT R S G Sbjct: 3339 DRTARDSDVPADG 3351 Score = 529 bits (1362), Expect = e-147 Identities = 404/1177 (34%), Positives = 540/1177 (45%), Gaps = 122/1177 (10%) Query: 1040 ATRL-SRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPV 1098 ATRL SR+ A AG +R T +++APA + D LPL+ Sbjct: 1125 ATRLISRI--RATAGAEVPIRRVFEAPTVAELAPALTDGGRARAAVTARPRPDRLPLSFA 1182 Query: 1099 QQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGE 1158 Q+ L F + +Y + + +TG +D L A+ VVARH +L F E Sbjct: 1183 QRRLWFIHQYEGP--SPLYNIPAALRLTGPVDGAALSAALGDVVARHESLRTVFAEDAHG 1240 Query: 1159 PVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQ 1218 P QV+ + A R L D P+ L R DL RA L+R + + Sbjct: 1241 PHQVILSAERAAPRLKTLDSD---PERLAADLARTARHTF-DLTRDVPLRATLLRVAPEE 1296 Query: 1219 HRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNFVNWLXXXXXXX 1271 H +L HHI DGWSL L +++ Y P Y ++ W Sbjct: 1297 HVLLLVLHHIAGDGWSLAPLARDLGTAYAARTAGTAPDWAPLPVQYADYTLWQRELLGAD 1356 Query: 1272 XXXX--------------WREVLDGFETPTLVAPPGVPGPRGIES------YRVSAETTR 1311 WRE L G L P P P ++ V A R Sbjct: 1357 GNGAGTGDGGEGARQLAHWREALAGLPE-RLELPSDRPRPARRDNSGARLDVSVPAGLHR 1415 Query: 1312 ALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINT 1371 +L LA T++ VLQAA LL R+ DV G+ ++GR A E++VG +NT Sbjct: 1416 SLAALAAETRTSVFMVLQAALAGLLTRLGAGEDVPIGSTIAGRTD--AAVENLVGFFVNT 1473 Query: 1372 VPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQLFDTLFLY 1425 + +R D +LL +++ H+ + + + H LF + + Sbjct: 1474 LVLRTDTGGDPAFRELLSRVRERDLAAYAHQDVPFERLVEAVNPDRATSHHPLFQVMLTF 1533 Query: 1426 ESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMAL----------PGHELGL--RVEYD 1473 ++ D +G T H LS L G + GL VE+ Sbjct: 1534 DTTQQDALGELGRLPGITTSLLPV---HTGLSRFDLVFAFDERRDAAGGQAGLDLAVEFS 1590 Query: 1474 TSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDS 1533 T +FD + L +R LL + DP RL +DV+ E L ANR + Sbjct: 1591 TELFDAGTVRALTERLLLLLTQVAADPGVRLGDLDVLLPGEHHDLLVAANRPGTAPASPA 1650 Query: 1534 PQS-----------------IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANL 1576 P S +PE+F RQ R P+ A+TFEG SL+Y EL+ AN+LA L Sbjct: 1651 PASPEPASPEPASPAPGTATLPELFERQAARHPDRTALTFEGTSLSYAELNARANRLARL 1710 Query: 1577 LAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAA 1636 L G P VAL +PRSA+ +VA+LAV+K+GAAY+P+DP PA RL L D+ P A Sbjct: 1711 LTARGIGPDALVALALPRSAELVVALLAVVKSGAAYVPLDPGYPADRLAHALSDSAPAAL 1770 Query: 1637 VTTGDLRSRFDGFDLQVVEVDDPA-----------VEIYPSTTLLTP------SPDDIAY 1679 +T R ++ + +D PA + +P+T L P D AY Sbjct: 1771 LTDRATAGRLPAHEVPRIVLDAPAPADGGTTGGDPADAHPATDLAQGERVRPLDPRDTAY 1830 Query: 1680 MIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALL 1739 +IYTSG+TG PKGVA+ HGNV ++ VW+ +HS FD SVWE+WG LL Sbjct: 1831 VIYTSGSTGRPKGVAVPHGNVVRLFSATAPWFGFDEHDVWTLFHSYAFDFSVWELWGPLL 1890 Query: 1740 HGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMM------SPEGLEGTALVVA 1793 HGGRLV+VP + P ALL E V VL QTPSA + +P L +V Sbjct: 1891 HGGRLVVVPHDVTRDPAAFLALLARERVTVLNQTPSAFHQLAAADRENPTELALRTVVFG 1950 Query: 1794 GEACPTEVVDRW----AVDR-VMINAYGPTESTIYA---AISAPLSPGSDVVPIGSPVPK 1845 GEA + W A D ++N YG TE+T++ A+ + S IG +P Sbjct: 1951 GEALDLSRLADWYERHAEDAPALVNMYGITETTVHVSHFALDRATAAASSASTIGVNIPD 2010 Query: 1846 GATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACP----FGEPGARMY 1901 +VLD+ LRP PGV GE+Y+A LT RF A P FGE G RMY Sbjct: 2011 LRVYVLDDRLRPTAPGVTGEMYVAGAGLARGYLGRPALTADRFPADPYAALFGERGTRMY 2070 Query: 1902 RTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGD 1961 RTGDL R DG L YLGRAD+QVKIRG+RIE GEI+A L+ VD V+ARED GD Sbjct: 2071 RTGDLARRRTDGGLDYLGRADQQVKIRGFRIEPGEIEAVLAAHPAVDDVAVVAREDVQGD 2130 Query: 1962 KRLVGY-ITGT-ADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ 2019 RLV Y +TG+ A A LP +M+P+A VTL+ LPLT NGKLD +ALPAP + Sbjct: 2131 PRLVAYVVTGSGATARALHDHAAGHLPDHMLPSAFVTLDVLPLTPNGKLDTKALPAPAHA 2190 Query: 2020 SAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADL 2079 RAP E+ L +FA VLGV R A R+ + L +L Sbjct: 2191 GQVTGRAPRGPREEILCALFAEVLGVPRLTVDDSFFDLGGHSLLATRLAGRIRGTLGVEL 2250 Query: 2080 SVRTLFEAPTVAKLSLHVE--------HDAGERTDRV 2108 SVR LFE PTVA LS ++ AGER +R+ Sbjct: 2251 SVRRLFETPTVAGLSAALDGAERSGTGPTAGERPERL 2287 Score = 469 bits (1206), Expect = e-129 Identities = 350/983 (35%), Positives = 467/983 (47%), Gaps = 102/983 (10%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPV-----------------TI 43 + A+P R L D+L EH + V NR P P T+ Sbjct: 1613 VAADPGVR-LGDLDVLLPGEHHDLLVAANRPGTAPASPAPASPEPASPEPASPAPGTATL 1671 Query: 44 PALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGE 103 P LF Q R PD AL S +Y EL+ +NRLA +L G P A VA +PRS E Sbjct: 1672 PELFERQAARHPDRTALTFEGTSLSYAELNARANRLARLLTARGIGPDALVALALPRSAE 1731 Query: 104 AILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDM- 162 ++++L+V+K+GAAY+P+DP +P R+ +SD+ P A LT RL +++ I + Sbjct: 1732 LVVALLAVVKSGAAYVPLDPGYPADRLAHALSDSAPAALLTDRATAGRLPAHEVPRIVLD 1791 Query: 163 -----------ADPAIDRRPSDALSGPR-----PDDLAYMTYTSGTTGVPKAVAVTHHNV 206 DPA +D G R P D AY+ YTSG+TG PK VAV H NV Sbjct: 1792 APAPADGGTTGGDPADAHPATDLAQGERVRPLDPRDTAYVIYTSGSTGRPKGVAVPHGNV 1851 Query: 207 TQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHN 266 +L SA VW+ +HS FD SVWE+WG LLHGGRLVVVP V P Sbjct: 1852 VRLFSATAPWFGFDEHDVWTLFHSYAFDFSVWELWGPLLHGGRLVVVPHDVTRDPAAFLA 1911 Query: 267 LLITEKVSVLCQTPSAAGML------SPEGLESTTLIVAGEACPTELVDRW-----APGR 315 LL E+V+VL QTPSA L +P L T++ GEA + W Sbjct: 1912 LLARERVTVLNQTPSAFHQLAAADRENPTELALRTVVFGGEALDLSRLADWYERHAEDAP 1971 Query: 316 VMINAYGPTEATIYA---AMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGEL 372 ++N YG TE T++ A+ ++VLD LRP GV GE+ Sbjct: 1972 ALVNMYGITETTVHVSHFALDRATAAASSASTIGVNIPDLRVYVLDDRLRPTAPGVTGEM 2031 Query: 373 YVAGHGVATGYIGRPDLTASRFVACP----FGETGERMYRTGDLVRWGSDGQLEYLGRAD 428 YVAG G+A GY+GRP LTA RF A P FGE G RMYRTGDL R +DG L+YLGRAD Sbjct: 2032 YVAGAGLARGYLGRPALTADRFPADPYAALFGERGTRMYRTGDLARRRTDGGLDYLGRAD 2091 Query: 429 EQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGY-ITGTADPAQ-LRTA 486 +QVKIRG+RIE GEI+A LA VD V+ARED GD RLV Y +TG+ A+ L Sbjct: 2092 QQVKIRGFRIEPGEIEAVLAAHPAVDDVAVVAREDVQGDPRLVAYVVTGSGATARALHDH 2151 Query: 487 LAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVY 546 A LP +M+P+A V LD +PLT NGKLD +ALPAP + RAP P E+IL ++ Sbjct: 2152 AAGHLPDHMLPSAFVTLDVLPLTPNGKLDTKALPAPAHAGQVTG-RAPRGPREEILCALF 2210 Query: 547 AQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXXXXXXXX 605 A+VLGV R+ VDDSFFDLGG S+L+ ++ R R G++ R +F T Sbjct: 2211 AEVLGVPRLTVDDSFFDLGGHSLLATRLAGRIRGTLGVELSVRRLFETPTVAGLSAALDG 2270 Query: 606 XXESHVVDEGVGPVV-----------ATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDD 654 S G GP A + +L +++GP+ +N T + + Sbjct: 2271 AERS-----GTGPTAGERPERLPLSYAQQRLWFLHQLEGPSPTYNITGALRLTGDLDPGA 2325 Query: 655 VVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTD--DVLVE 712 + Q ++ RH +LR + + L A G R L D D D +E Sbjct: 2326 LRAAFQDVVTRHESLRTVFSEDGHGARQTVL-----DAAGVRFELPVADVSEDRLDARLE 2380 Query: 713 --ARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIAWAQHCTG 767 AR+ D V A R ++ L+LM+HH+A DG S L+ DL A+ Sbjct: 2381 EAARHCFDLTTDIPVRAELFRLGAREHVLLLMVHHIAGDGWSLGPLIRDLAAAYTARAAR 2440 Query: 768 QSIE---LPAGGTSFARWSALL---AEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDT 821 ++ + LP FA W A A + R LA A+ +P L + D Sbjct: 2441 RAPDWAPLPVQYADFALWQRAALGDAADATSPAGRQLAHWKEALAGLPDRL-ELPADRPL 2499 Query: 822 YVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVD 878 A + + L + E+ R V +L A T D P+G Sbjct: 2500 PAVASHRGGRVPLTVPAPLHSGVAELARESRTSVFMVLQAALAALLTRMGAGEDVPLGTP 2559 Query: 879 VEGHGRYDELASDVDLSRTVGWF 901 V G G D + + VG+F Sbjct: 2560 VAGRG-------DDAVDQVVGFF 2575 Score = 456 bits (1173), Expect = e-125 Identities = 361/1059 (34%), Positives = 488/1059 (46%), Gaps = 97/1059 (9%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ QQ L F Y L + + G LD LR A+ VVARH +L F Sbjct: 4849 IPLSYAQQRLWFLHQLEGPSA--TYNTVLTLRLGGALDVDALRAAISDVVARHESLRTVF 4906 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALI 1212 E Q++ + + + + EI DL + R +L Sbjct: 4907 TEDERGAYQIVLPVEAASTPFTVVD----VAEEEIGDRLDEAVGHCFDLAQELPARTSLF 4962 Query: 1213 RTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNWLX 1265 R S +H +L HHI D WS L Q++ A Y P AP Y ++ W Sbjct: 4963 RVSEREHVLLLLIHHIASDAWSRAPLAQDLTAAYAARVRSEAPMWAPLTVQYADYALWQQ 5022 Query: 1266 XXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTR 1311 W++ L G + PT P V G G + V E Sbjct: 5023 EILGDDTDADSLAGRQLAYWKQQLAGLPEQLDLPTDRPRPAVAGYSGDRVPFTVPTELHT 5082 Query: 1312 ALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINT 1371 L ELAR+ +T+ V+QAA LL R+ D+ GT V+GR D A+ ++GL INT Sbjct: 5083 RLTELARATNTSAFMVIQAAVAVLLTRLGAGEDIPIGTPVAGRTDD--AADDLIGLFINT 5140 Query: 1372 VPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHL-------ALNDIHHVSGHEQLFDTLFL 1424 + +R S D T LL +++ H+ L ALN +S H LF L Sbjct: 5141 LVLRTDTSGDPTFRRLLDRVRDTDLAAYAHQDLPFERLVEALNPARTLS-HHPLFQVLLT 5199 Query: 1425 YESYPIDTSAFMGVQELAVTEFNNREYNH----YPLSVMALPGHELGLR-------VEYD 1473 + + + A + EL RE + LS + R +++ Sbjct: 5200 FNNTDHE-GALKDISELPGLTVALREVQRTSSKFDLSFGFAESFDTSRRPQGIEAALDFS 5258 Query: 1474 TSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQ-LDEWANRAVLTQPVD 1532 T + D + + DRF R+LEA+ P R + +++++D ER + L EW TQ Sbjct: 5259 TELLDRRSAQAIADRFLRVLEAVTTAPDRPIGAVELMDPAERERVLVEW--NGAPTQLPG 5316 Query: 1533 SPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMV 1592 +P + E+ + Q P+A AV +G +L Y ELD ANQLA L G VA+ + Sbjct: 5317 TP--LHELISEQARLTPDAVAVVCDGTTLTYAELDRRANQLARHLLGEGLGAEDFVAIAL 5374 Query: 1593 PRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQ 1652 +S DA++++LAVLKTGAAYLPIDP PA R+ +ML DA+P +T + +D Sbjct: 5375 AKSLDAVISMLAVLKTGAAYLPIDPDYPAERITYMLDDAQPALTLTAPIPPASYDS---- 5430 Query: 1653 VVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELP 1712 P EI S AYMIYTSG+TG PKGV I H + L Sbjct: 5431 -----RPTSEITDVERRSPWSARHAAYMIYTSGSTGRPKGVVIEHHALATYLHRARNTYT 5485 Query: 1713 AGPGAVWSQWHS-LVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLY 1771 A G + HS L FD+++ +W L GG + + A L + Sbjct: 5486 AMTGV--TVLHSPLAFDLTITALWTPLTAGGTVHLTSLEEAEVQPSL-----------IK 5532 Query: 1772 QTPSAVRMMS--PEGLEGT-ALVVAGEACPTEVVDRWAVDRV---MINAYGPTESTI--- 1822 TPS + +++ PE + L++ GEA T+ + W +INAYGPTEST+ Sbjct: 5533 ATPSHLPLLTTLPETASPSHTLILGGEALHTDHLATWRTQHPGAQIINAYGPTESTVNIT 5592 Query: 1823 --YAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXX 1880 + + P P VPIG P +VLD LRPV PGV GELYLA Sbjct: 5593 DHHVSEDTPDGP----VPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGR 5648 Query: 1881 XXLTGTRFVACPFGE-PGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQA 1939 LT RF A P PGARMYRTGDL W DG L Y GRAD Q+K+RG+RIE GEI+ Sbjct: 5649 PALTAERFTANPHSSTPGARMYRTGDLAHWNHDGHLTYDGRADHQIKLRGHRIEPGEIET 5708 Query: 1940 ALSDVDGVDQAVVIAREDRPGDKRLVGYI----TGTADPAAARSELTNRLPAYMVPAAVV 1995 L+ G+ Q V RED PGD+RLV Y+ + D R L + LP YM P+A V Sbjct: 5709 TLTAQTGITQTTVQLREDTPGDQRLVAYLVVNDSTEYDEPTLRDALASALPDYMRPSAYV 5768 Query: 1996 TLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXX 2055 TL+ LPLT NGKLDR ALPAP Y ++ R P T E+ L +FA VLGV+ Sbjct: 5769 TLDALPLTPNGKLDRTALPAPAYSASTTGRTPRTPREEILCTLFAEVLGVDLVTIDDNFF 5828 Query: 2056 XXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 A R+ + TAL +LSVR FE PT+A LS Sbjct: 5829 DLGGHSLLATRLVSRARTALGVELSVRQFFETPTIAGLS 5867 Score = 451 bits (1161), Expect = e-124 Identities = 355/1102 (32%), Positives = 528/1102 (47%), Gaps = 111/1102 (10%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ QQ L F Y + + +TG LD L+ A++ ++ARH +L + Sbjct: 5889 IPLSYAQQRLWFLHQLEGPSA--TYNIPTTLRLTGTLDTDALQSALNDLLARHESLRTTY 5946 Query: 1153 VEQFGEPVQVLTA-DP-MIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 E P QV+ A +P M+ +D T + E++ + +A DL RA Sbjct: 5947 TEDGEGPRQVIHAWEPGMLPLGVVD------TGEGELDAMLSAGVHHAFDLTAGIPVRAT 6000 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNW 1263 L R S +H +L HHI D WS L ++ A Y +PA P Y ++ W Sbjct: 6001 LFRISEQEHVLLLLIHHIATDAWSRTPLGHDLAAAYSARCAGDVPAWEPLPVQYADYALW 6060 Query: 1264 LXXXXXXXXXXX---------WREVL----DGFETPTLVAPPGVPGPRGIE-SYRVSAET 1309 W L + + PT P V G ++ + A+ Sbjct: 6061 QREVLGDEGDADAPAGRQLAYWTRQLADLPEQLDLPTDRPRPAVASQDGDRVAFSLDADL 6120 Query: 1310 TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLI 1369 L ELAR+ H++ V+QAA LL R+ D+ GT V+GR D E++VG + Sbjct: 6121 YVRLTELARATHSSTFMVVQAALAVLLTRLGAGEDIPIGTPVAGRTDD--ATENLVGFFV 6178 Query: 1370 NTVPIRAKVSADTTVGDLLRQ-----LQSHHNDTLEHEHL--ALNDIHHVSGHEQLFDTL 1422 NT+ +R S + T +LL + L ++ + L E L ALN ++ H LF + Sbjct: 6179 NTLVLRNDTSGNPTFRELLEETRRTDLAAYAHQDLPFERLVEALNPARTLA-HHPLFQVM 6237 Query: 1423 FLYESYPIDTSAFMGVQELAVTEFNNR------EYNHYPLSVMALPGHELGLR--VEYDT 1474 + + D A + + L V +R + V G GL +++ T Sbjct: 6238 LILSTAETDPDASLALPGLRVGAERSRLGAAKVDLAFALAEVRDGEGRSTGLTGALDFRT 6297 Query: 1475 SVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSP 1534 +FD S +L++RF R LEA++ DP RLS + V+ ER L + +L + +D+ Sbjct: 6298 DLFDRSTARSLVERFVRTLEAVVADPGVRLSRVPVLTGSERRSLLDRGTGPLL-EGLDA- 6355 Query: 1535 QSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPR 1594 ++PE+FA Q R P APA+ G +++Y ELD N+LA LL G PG V +++ R Sbjct: 6356 -TLPELFAEQALRTPGAPALVRGGTTVSYAELDLRTNRLARLLRQQGVRPGTPVVMLMER 6414 Query: 1595 SADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVV 1654 S +VA LA+ K G AY+P+ + P R+ ++ D +T +R +V+ Sbjct: 6415 SPAHVVATLAIAKAGGAYVPLHDTYPLDRMRHVVADTAATLILTDRAEAARAGQLGARVM 6474 Query: 1655 EVDD-------PAVEIYPSTTLLTPS----------------PDDIAYMIYTSGTTGVPK 1691 VD+ + P T T + P D+AY++YTSG+TGVPK Sbjct: 6475 VVDEFGAAPSGSEADAAPGTGTGTGTGSRSGYVDDAPEVGLRPQDLAYVMYTSGSTGVPK 6534 Query: 1692 GVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESI 1751 GVA+TH V ++ + H+ FDVS +E+W L+ GG +V+ P Sbjct: 6535 GVAVTHRGVVDLVRDHCWRPGVHERVLLHAPHA--FDVSCYEMWVPLVSGGTVVVAPPGH 6592 Query: 1752 AGSPDDLHALLVSEGVNVLYQTPSAVRMM---SPEGLEGTALVVAGEACPTEVVDRWAVD 1808 P + L+ + + ++ T R++ +PE G V+ G +VV AV Sbjct: 6593 L-DPAAITDLITAHDITAIHLTAGFFRVVAEEAPECFAGVREVLTG----GDVVSPAAVA 6647 Query: 1809 RVMI--------NAYGPTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRP 1857 RV+ + YGPTE+T+ ++AP +P+G +VLD +L+P Sbjct: 6648 RVLAHHPRIVLRHLYGPTETTLCVTQHEVTAPYEARGS-LPVGRATGNTRAYVLDRYLQP 6706 Query: 1858 VPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQY 1917 VP GV GEL+++ LT RFVA P+G G RMYRTGDLVR+ G+L+Y Sbjct: 6707 VPAGVPGELFISGSGLARGYLDRPDLTCERFVADPYGGSGERMYRTGDLVRYNAAGELEY 6766 Query: 1918 LGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT------GT 1971 L RAD+QVKIRG+R+ELGEI+A L+ + QA V+ REDRPGD+RLVGY+ G Sbjct: 6767 LARADDQVKIRGFRVELGEIEAVLATRPELAQAAVVVREDRPGDRRLVGYVVAAAGRDGE 6826 Query: 1972 ADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETET 2031 DP A R+ LP YMVP+A V L TLPLT NGKLDR+ALPAP+Y +A RA T Sbjct: 6827 VDPDALRAFSRQALPDYMVPSAFVVLGTLPLTANGKLDRKALPAPDYGAASTGRAARTPA 6886 Query: 2032 EKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVA 2091 E+ L +FA VLG+ ++++ + A L+VR +FE + A Sbjct: 6887 EELLCTLFAQVLGLSAVGVDDGFFDLGGDSILSIQLVSRARAA-GLALAVRDVFEHQSTA 6945 Query: 2092 KLSLHVEHDAGERTDRVSFAAV 2113 +L A TDR A+V Sbjct: 6946 RL-------AAALTDRDDAASV 6960 Score = 407 bits (1047), Expect = e-111 Identities = 323/917 (35%), Positives = 442/917 (48%), Gaps = 82/917 (8%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R + + +L+D E +++ V N A PG TP + L +EQ PDAVA+V + Sbjct: 5287 RPIGAVELMDPAERERVLVEWNGAPTQLPG-TP--LHELISEQARLTPDAVAVVCDGTTL 5343 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 TY ELD +N+LA L G VA + +S +A++S+L+VLKTGAAYLP+DP +P Sbjct: 5344 TYAELDRRANQLARHLLGEGLGAEDFVAIALAKSLDAVISMLAVLKTGAAYLPIDPDYPA 5403 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMT 187 RI +M+ DA+P LT + D + I + R P A AYM Sbjct: 5404 ERITYMLDDAQPALTLTAPIPPASYDSRPTSEITDVER---RSPWSARHA------AYMI 5454 Query: 188 YTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHS-LVFDVSVWEIWGALLH 246 YTSG+TG PK V + HH + + + G + HS L FD+++ +W L Sbjct: 5455 YTSGSTGRPKGVVIEHHALATYLHRARNTYTAMTGV--TVLHSPLAFDLTITALWTPLTA 5512 Query: 247 GGRLVVVP-ESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLS--PEGLE-STTLIVAGEA 302 GG + + E P S++ TPS +L+ PE S TLI+ GEA Sbjct: 5513 GGTVHLTSLEEAEVQP------------SLIKATPSHLPLLTTLPETASPSHTLILGGEA 5560 Query: 303 CPTELVDRWA---PGRVMINAYGPTEATIYAA---MSEPLXXXXXXXXXXXXXXXXXLFV 356 T+ + W PG +INAYGPTE+T+ +SE ++V Sbjct: 5561 LHTDHLATWRTQHPGAQIINAYGPTESTVNITDHHVSEDTPDGPVPIGRPFANTQ--VYV 5618 Query: 357 LDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGET-GERMYRTGDLVRW 415 LD LRP GV GELY+AG +A GY+GRP LTA RF A P T G RMYRTGDL W Sbjct: 5619 LDSALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSSTPGARMYRTGDLAHW 5678 Query: 416 GSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYI- 474 DG L Y GRAD Q+K+RG+RIE GEI+ L G+ Q V RED PGD+RLV Y+ Sbjct: 5679 NHDGHLTYDGRADHQIKLRGHRIEPGEIETTLTAQTGITQTTVQLREDTPGDQRLVAYLV 5738 Query: 475 ---TGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDY 531 + D LR ALA +LP YM P+A V LD +PLT NGKLDR ALPAP Y SA+ Sbjct: 5739 VNDSTEYDEPTLRDALASALPDYMRPSAYVTLDALPLTPNGKLDRTALPAPAY-SASTTG 5797 Query: 532 RAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDI 590 R P TP E+IL ++A+VLGV+ V +DD+FFDLGG S+L+ ++V+RAR A G++ R Sbjct: 5798 RTPRTPREEILCTLFAEVLGVDLVTIDDNFFDLGGHSLLATRLVSRARTALGVELSVRQF 5857 Query: 591 FVEQTXXXXXXXXXXXXESHVV------DEGVGPVVATPIMRWLREVDGPTGQFNQTVIT 644 F T + E + A + +L +++GP+ +N Sbjct: 5858 FETPTIAGLSGAFDRAGRARAALTARPRPERIPLSYAQQRLWFLHQLEGPSATYNIPTTL 5917 Query: 645 QAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDE----WSLLVPEAGAVGARECLR 700 + + D + L LL RH +LR + E + W + G V E Sbjct: 5918 RLTGTLDTDALQSALNDLLARHESLRTTYTEDGEGPRQVIHAWEPGMLPLGVVDTGE--G 5975 Query: 701 TVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDL 757 +DA+ + + D AG V A R + Q L+L+IHH+A D S L DL Sbjct: 5976 ELDAM---LSAGVHHAFDLTAGIPVRATLFRISEQEHVLLLLIHHIATDAWSRTPLGHDL 6032 Query: 758 NIAWAQHCTGQS---IELPAGGTSFARWS-ALLAEHAKTDTV--RDLADAWRAVTSVPQA 811 A++ C G LP +A W +L + D R LA R + +P+ Sbjct: 6033 AAAYSARCAGDVPAWEPLPVQYADYALWQREVLGDEGDADAPAGRQLAYWTRQLADLPEQ 6092 Query: 812 LP-------PVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAW 864 L P D A L A L V T E+ A + ++ A + Sbjct: 6093 LDLPTDRPRPAVASQDGDRVAFSLDADLYVRLT-----ELARATHSSTFMVVQAALAVLL 6147 Query: 865 TEFLNRSDTPIGVDVEG 881 T D PIG V G Sbjct: 6148 TRLGAGEDIPIGTPVAG 6164 Score = 405 bits (1041), Expect = e-110 Identities = 322/933 (34%), Positives = 456/933 (48%), Gaps = 90/933 (9%) Query: 6 STRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDR 65 S R + D LD +++ V N A PG TP + L +EQ PDAVA+V Sbjct: 4245 SDRPVAHLDTLDPAVRERVLVEWNGAPTQLPG-TP--LHELISEQARLTPDAVAVVCDGT 4301 Query: 66 SWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAH 125 S TY ELD +N+LA L G VA + +S +A++S+L+VLKTGAAYLP+DP + Sbjct: 4302 SLTYAELDGGANQLARHLLGEGLGAEDFVAIALAKSLDAVISMLAVLKTGAAYLPIDPDY 4361 Query: 126 PDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAY 185 P RI +M+ DA+P LT R + + + + R P A AY Sbjct: 4362 PAERITYMLDDARPALTLTEPVPVERYTGHSVTAVTDEER---RSPWSARHA------AY 4412 Query: 186 MTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHS-LVFDVSVWEIWGAL 244 M YTSG+TG PK V + HH + + + G + HS L FD+++ +W L Sbjct: 4413 MIYTSGSTGRPKGVVIEHHALATYLHRARNTYTAMTGV--TVLHSPLAFDLTITALWTPL 4470 Query: 245 LHGGRLVVVP-ESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLS--PEGLE-STTLIVAG 300 GG + + E + P S++ TPS +L+ PE S TLI+ G Sbjct: 4471 TSGGTVHLTSLEESDTQP------------SLIKATPSHLPLLTTLPETASPSHTLILGG 4518 Query: 301 EACPTELVDRWA---PGRVMINAYGPTEATI-----YAAMSEPLXXXXXXXXXXXXXXXX 352 EA T+ + W PG +INAYGPTE+T+ + P Sbjct: 4519 EALHTDHLVTWRTQHPGVQIINAYGPTESTVNITDHHVGEDTP----DGPVPIGRPFANT 4574 Query: 353 XLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGET-GERMYRTGD 411 ++VLD LRP GV GELY+AG +A GY+GRP LTA RF A P T G RMYRTGD Sbjct: 4575 QVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSSTPGARMYRTGD 4634 Query: 412 LVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLV 471 L W G L Y GRAD Q+K+RG+RIE GEI+A L G+ QA V RED+PGD+RLV Sbjct: 4635 LAHWNHHGHLTYDGRADHQIKLRGHRIEPGEIEATLTAQTGITQATVQLREDQPGDQRLV 4694 Query: 472 GYI----TGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSA 527 Y+ + D +R AL +LP YMVP+A+V LD +PLT NGKLDR ALPAP Y SA Sbjct: 4695 AYLVVNDSTEYDEKTVRDALTSALPDYMVPSALVTLDALPLTPNGKLDRTALPAPAY-SA 4753 Query: 528 ANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCR 586 + RAP TP E++L ++A+VLGV+ V +DD+FFDLGG S+L+ ++V+R R A G++ Sbjct: 4754 STAGRAPRTPREEVLCTLFAEVLGVDLVTIDDNFFDLGGHSLLATRLVSRTRTALGVELS 4813 Query: 587 PRDIFVEQTXXXXXXXXXXXXESHVV------DEGVGPVVATPIMRWLREVDGPTGQFNQ 640 R +F T E + A + +L +++GP+ +N Sbjct: 4814 IRQLFETPTVAGLAEALDASGTVRTALTARPRPERIPLSYAQQRLWFLHQLEGPSATYN- 4872 Query: 641 TVITQAPAGVTEDDVV-VILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECL 699 TV+T G + D + + ++ RH +LR T+++ + +++P E Sbjct: 4873 TVLTLRLGGALDVDALRAAISDVVARHESLRTVF--TEDERGAYQIVLPV-------EAA 4923 Query: 700 RTVDALTDDVLVEARNRLDPAAG----------AMVSAVWVRETSQ-LVLMIHHLAVDGV 748 T + D E +RLD A G A S V E L+L+IHH+A D Sbjct: 4924 STPFTVVDVAEEEIGDRLDEAVGHCFDLAQELPARTSLFRVSEREHVLLLLIHHIASDAW 4983 Query: 749 SWRILLEDLNIAWAQHCTGQS---IELPAGGTSFARW-SALLAEHAKTDTV--RDLADAW 802 S L +DL A+A ++ L +A W +L + D++ R LA Sbjct: 4984 SRAPLAQDLTAAYAARVRSEAPMWAPLTVQYADYALWQQEILGDDTDADSLAGRQLAYWK 5043 Query: 803 RAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVA 859 + + +P+ L + D AG + +L L E+ A ++ A Sbjct: 5044 QQLAGLPEQL-DLPTDRPRPAVAGYSGDRVPFTVPTELHTRLTELARATNTSAFMVIQAA 5102 Query: 860 FGLAWTEFLNRSDTPIGVDVEGHGRYDELASDV 892 + T D PIG V GR D+ A D+ Sbjct: 5103 VAVLLTRLGAGEDIPIGTPVA--GRTDDAADDL 5133 Score = 372 bits (954), Expect = e-100 Identities = 301/912 (33%), Positives = 421/912 (46%), Gaps = 81/912 (8%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFV-EQFGEPVQVL----------TADP---- 1167 + I G LD L A+ VA L +RF+ ++ G P + DP Sbjct: 37 LEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVP 96 Query: 1168 --MIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRA-ALIRTSGNQHRFVLT 1224 + R++DL G + P+ E ++ +R+ L +RP + AL G +H + L Sbjct: 97 YTPVLLRHIDLSGHE-DPEGEAQRWMDRDRATPLPL-DRPGLSSHALFTLGGGRHLYYLG 154 Query: 1225 FHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVN----------WLXXXXXXXXXX 1274 HHIVIDG S+ + + + Y R A P F + + Sbjct: 155 VHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRA 214 Query: 1275 XWREVLDGFETPTLVAPPGVPGPRG----IESYRVSAETTRALGELARSQHTTINTVLQA 1330 W + + P V+ G G R + S + E T LG A + V+ A Sbjct: 215 YWTGLFT--DRPEPVSLTGRGGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIA 272 Query: 1331 AWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQ 1390 L R TG RDV V+GR A A G++ N +P+R V + ++ Sbjct: 273 GVAAFLHRTTGARDVVVSVPVTGRYG--ANARITPGMVSNRLPLRLAVRPGESFARVVET 330 Query: 1391 LQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESY--PIDTSAFMGVQELAVTEFNN 1448 + + L H D+ G + Y P+D +G+ Sbjct: 331 VSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLM--------- 381 Query: 1449 REYNHYP---LSVMALPGHELGLRVEYDTS--VFDVSEIETLIDRFQRLLEAMIDDPARR 1503 R + P L+++ E GLRV+++ + V+ ++ L +RF R L + DPA Sbjct: 382 RSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAAT 441 Query: 1504 LSSMDVVDDDERTQ-LDEWANRAVLTQPVDSPQS-IPEVFARQVERDPEAPAVTFEGESL 1561 + + ++ DER + LD W + A + P++ +PE+FA + R P A+ +EG SL Sbjct: 442 VDEVALLTPDERERVLDGWNDTAH-----EVPETTLPELFAARAARTPGHEALVYEGTSL 496 Query: 1562 NYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPA 1621 Y ELD A +LA L GA P + VA+ V RSA+ +VA+LAVLK+GAAY+P+DP PA Sbjct: 497 TYAELDARAERLAGALTARGAGPERFVAVAVERSAELVVALLAVLKSGAAYVPVDPGYPA 556 Query: 1622 ARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVE-------IYPSTTL--LTP 1672 R+ +L DA + +TT D R G + +D+PA P TL P Sbjct: 557 DRIAHILRDAGAMLVLTTRDTAERLPGDGTPRLLLDEPAAAGTTAAGAPAPPGTLPRALP 616 Query: 1673 SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVW 1732 +P AY+IYTSG+TG PKGV I+H + L + P Q FDVSVW Sbjct: 617 APGHPAYVIYTSGSTGRPKGVVISHRAIVNRLAWMQDTYGLEPSDRVLQKTPSGFDVSVW 676 Query: 1733 EIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPE----GLEGT 1788 E + L+ G LV+ P L + EGV L+ PS + + E L G Sbjct: 677 EFFWPLVQGATLVVARPGGHTDPAYLAGTVRREGVTTLHFVPSMLDVFLREPAAAALGGA 736 Query: 1789 ALV----VAGEACPTEVVDRWAV--DRVMINAYGPTESTIYAAI-SAPLSPGSDVVPIGS 1841 V +GEA P E+ R+ D + N YGPTE+ + G VPIG Sbjct: 737 TPVRRVFCSGEALPAELRARFRAVSDVPLHNLYGPTEAAVDVTYWPCAEDTGDGPVPIGR 796 Query: 1842 PVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMY 1901 PV +VLD LRPVP GV GELY+A L+ RF A P G PG+RMY Sbjct: 797 PVWNTRMYVLDAALRPVPAGVPGELYIAGVQLARGYLGRPALSAERFTADPHGAPGSRMY 856 Query: 1902 RTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGD 1961 RTGDL RW DG L YLGRAD QVK+RG+RIELGEI+AAL + QA V+ REDRPGD Sbjct: 857 RTGDLARWNHDGSLDYLGRADHQVKLRGFRIELGEIEAALVRQPEIAQAAVVLREDRPGD 916 Query: 1962 KRLVGYITGTAD 1973 +RLV Y D Sbjct: 917 QRLVAYTVPARD 928 Score = 290 bits (742), Expect = 2e-75 Identities = 197/512 (38%), Positives = 259/512 (50%), Gaps = 28/512 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 + A+P+ T+ LL DE +++ N P T+P LFA + R P AL Sbjct: 434 LAADPAA-TVDEVALLTPDERERVLDGWNDTAHEVP---ETTLPELFAARAARTPGHEAL 489 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V S TY ELD + RLA L GA P VA + RS E ++++L+VLK+GAAY+P Sbjct: 490 VYEGTSLTYAELDARAERLAGALTARGAGPERFVAVAVERSAELVVALLAVLKSGAAYVP 549 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGP-- 178 VDP +P RI ++ DA + LTT D RL + + +PA + P Sbjct: 550 VDPGYPADRIAHILRDAGAMLVLTTRDTAERLPGDGTPRLLLDEPAAAGTTAAGAPAPPG 609 Query: 179 -------RPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSL 231 P AY+ YTSG+TG PK V ++H + ++ + P Q Sbjct: 610 TLPRALPAPGHPAYVIYTSGSTGRPKGVVISHRAIVNRLAWMQDTYGLEPSDRVLQKTPS 669 Query: 232 VFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGL 291 FDVSVWE + L+ G LVV + P L + E V+ L PS + E Sbjct: 670 GFDVSVWEFFWPLVQGATLVVARPGGHTDPAYLAGTVRREGVTTLHFVPSMLDVFLREPA 729 Query: 292 ESTT--------LIVAGEACPTELVDRW-APGRVMI-NAYGPTEATI---YAAMSEPLXX 338 + + +GEA P EL R+ A V + N YGPTEA + Y +E Sbjct: 730 AAALGGATPVRRVFCSGEALPAELRARFRAVSDVPLHNLYGPTEAAVDVTYWPCAEDTGD 789 Query: 339 XXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACP 398 ++VLD LRP P GV GELY+AG +A GY+GRP L+A RF A P Sbjct: 790 GPVPIGRPVWNTR--MYVLDAALRPVPAGVPGELYIAGVQLARGYLGRPALSAERFTADP 847 Query: 399 FGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVV 458 G G RMYRTGDL RW DG L+YLGRAD QVK+RG+RIELGEI+AAL + + QA V Sbjct: 848 HGAPGSRMYRTGDLARWNHDGSLDYLGRADHQVKLRGFRIELGEIEAALVRQPEIAQAAV 907 Query: 459 IAREDRPGDKRLVGYITGTADPAQLRTALAES 490 + REDRPGD+RLV Y D L AE+ Sbjct: 908 VLREDRPGDQRLVAYTVPARDADTLTGPPAEA 939 Score = 136 bits (343), Expect = 4e-29 Identities = 140/486 (28%), Positives = 202/486 (41%), Gaps = 51/486 (10%) Query: 479 DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPA 538 D A L L E LP YMVP+A V L +P+T NGKLDRRALPAP A RAP TP Sbjct: 1034 DGAVLAARLRELLPGYMVPSAFVALPRLPVTPNGKLDRRALPAPAESGRAAG-RAPRTPG 1092 Query: 539 EQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGIQCRPRDIFVEQTXX 597 E++L ++A+VLGV V VDD FFDLGG S+L+ ++++R RA AG + R +F T Sbjct: 1093 EELLCALFAEVLGVAEVRVDDGFFDLGGHSLLATRLISRIRATAGAEVPIRRVFEAPTVA 1152 Query: 598 XXXXXXXXXXESHVVDEGVGPVVATPI------MRWLREVDGPTGQFNQTVITQAPAGVT 651 + P+ + ++ + +GP+ +N + V Sbjct: 1153 ELAPALTDGGRARAAVTARPRPDRLPLSFAQRRLWFIHQYEGPSPLYNIPAALRLTGPVD 1212 Query: 652 EDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA----LTD 707 + L ++ RH +LR + + L A A L+T+D+ L Sbjct: 1213 GAALSAALGDVVARHESLRTVFAEDAHGPHQVIL-----SAERAAPRLKTLDSDPERLAA 1267 Query: 708 DVLVEARNRLDPAAGAMVSAVWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQH 764 D+ AR+ D + A +R E L+L++HH+A DG S L DL A+A Sbjct: 1268 DLARTARHTFDLTRDVPLRATLLRVAPEEHVLLLVLHHIAGDGWSLAPLARDLGTAYAAR 1327 Query: 765 CTGQSIE---LPAGGTSFARWSALL----AEHAKT----DTVRDLADAWRAVTSVPQALP 813 G + + LP + W L A T + R LA A+ +P+ L Sbjct: 1328 TAGTAPDWAPLPVQYADYTLWQRELLGADGNGAGTGDGGEGARQLAHWREALAGLPERL- 1386 Query: 814 PVQPDTDTYVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVAFGLAWTEFLNR 870 + D A LDV L L + A R V +L A T Sbjct: 1387 ELPSDRPRPARRDNSGARLDVSVPAGLHRSLAALAAETRTSVFMVLQAALAGLLTRLGAG 1446 Query: 871 SDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIV 930 D PIG + G +D + VG+F V L GD A ++ Sbjct: 1447 EDVPIGSTIAGR-------TDAAVENLVGFF---------VNTLVLRTDTGGDPAFRELL 1490 Query: 931 KAVKEQ 936 V+E+ Sbjct: 1491 SRVRER 1496 Score = 91.3 bits (225), Expect = 2e-15 Identities = 51/122 (41%), Positives = 65/122 (53%) Query: 1973 DPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETE 2032 D A + L LP YMVP+A V L LP+T NGKLDRRALPAP RAP T E Sbjct: 1034 DGAVLAARLRELLPGYMVPSAFVALPRLPVTPNGKLDRRALPAPAESGRAAGRAPRTPGE 1093 Query: 2033 KTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAK 2092 + L +FA VLGV A R+ + + A++ +R +FEAPTVA+ Sbjct: 1094 ELLCALFAEVLGVAEVRVDDGFFDLGGHSLLATRLISRIRATAGAEVPIRRVFEAPTVAE 1153 Query: 2093 LS 2094 L+ Sbjct: 1154 LA 1155 Score = 45.1 bits (105), Expect = 0.15 Identities = 71/311 (22%), Positives = 113/311 (36%), Gaps = 40/311 (12%) Query: 1054 ICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDV-----------LPLTPVQQGL 1102 + + R G L DV + T R L+ R D V PLTPV + Sbjct: 6922 LVSRARAAGLALAVRDVFEHQSTARLAAALTDRDDAASVPEAEAVPPYGPAPLTPVMARI 6981 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 G+G D + + +++ +D+ RL A+ V+ H L R + V+ Sbjct: 6982 A-----ELGLGGDDFNQSVVVSLPPAVDRDRLVPALQRVLDHHDALRLRVLPDGSTEVRA 7036 Query: 1163 LTADPMIAWRYLDLRGDDLTPDHE----IEQLCAA-ERSAVCDLLERPTFRAALIR---- 1213 + P + R T + +E CAA +R A E +A L+ Sbjct: 7037 PGSVPAADVLSVVTRAPGATGEARDALLVEAACAARDRLAPA---EGRMLQAVLVDGTDD 7093 Query: 1214 ------TSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHR-LPAAAPYRNFVNWL-- 1264 TSG +L HH+V+D + I++ ++ A Y G P +R + L Sbjct: 7094 TDGTGGTSGADGVLILVAHHLVVDSVTWSIVVPDLAAAYRGEEPAPVGTSWRQWATSLAR 7153 Query: 1265 --XXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRA-LGELARSQH 1321 W L G T L + G G S ++ TT A L L + Sbjct: 7154 LATDPRVEAETAHWEHTLTGAGTLRLDRGRDLQGDAGRISLDLAPHTTEALLTRLPGGVN 7213 Query: 1322 TTINTVLQAAW 1332 +++ VL A+ Sbjct: 7214 ASVHDVLLTAF 7224 >tr|D6ES40|D6ES40_STRLI Tax_Id=457428 SubName: Full=CDA peptide synthetase I;[Streptomyces lividans TK24] Length = 5605 Score = 1339 bits (3465), Expect = 0.0 Identities = 879/2190 (40%), Positives = 1175/2190 (53%), Gaps = 154/2190 (7%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVT-IPALFAEQVVR------ 53 + A+PS R + D+L E ++ VLT+ TP + FA+ V R Sbjct: 849 LVADPSRR-IGDVDVLGPRERER--------VLTEWNDTPRRPVQGTFADHVARHAAERP 899 Query: 54 ---APDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILS 110 A + + + TY EL+E +NRLA L GA P VA +PRS + +LS L+ Sbjct: 900 GHLAVETAGAAAPGGALTYGELNERANRLARALLARGAGPERFVAVALPRSADLVLSALA 959 Query: 111 VLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRL----------DQYDLAVI 160 K GAAYLPVDPAHP RI ++SDA P +TT+ L + L D + A Sbjct: 960 AFKAGAAYLPVDPAHPAERITHLVSDAAPTLIVTTSALAASLPDTGTPVLLLDTPETAAT 1019 Query: 161 DMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSG 220 A P D +D RP+ AYM YTSGTTG PK V VTH + L+ D +G Sbjct: 1020 LAALPGHDVTDADRPVPLRPEHPAYMIYTSGTTGRPKGVVVTHTGLPGLLDIFTRDCAAG 1079 Query: 221 PGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTP 280 PG Q S FD S WE+ LL G LVV P P+ L L + L T Sbjct: 1080 PGSRILQHLSPSFDASFWELAMGLLTGATLVVAPPETTPGPE-LAELATRHAATHLSLTT 1138 Query: 281 SAAGMLSPEGL-ESTTLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXX 339 S G+L P+ L + TL+V EA P ELV+RW+PGR M+N+YGPTE T+ + MS PL Sbjct: 1139 SVLGLLPPDSLPDGLTLVVGAEAIPPELVERWSPGRTMLNSYGPTETTVCSTMSGPLSGP 1198 Query: 340 XXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPF 399 ++VLD LRP P GV GELY AG +A GY R LTA RFVA PF Sbjct: 1199 AVPPIGSPVANSA-VYVLDAALRPVPPGVPGELYAAGAHLARGYHDRRALTAERFVANPF 1257 Query: 400 GETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVI 459 GE G R+YRTGDLVRW DGQLEYLGRAD QVKIRG RIE EI+A + + + +A VI Sbjct: 1258 GEPGSRLYRTGDLVRWRPDGQLEYLGRADTQVKIRGLRIEPTEIEAVITERPHLARAAVI 1317 Query: 460 AREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLD 515 REDRPGD+RLV Y+ T D A+LR AL E+LP +M+PTA VVLD +PLT+NGKLD Sbjct: 1318 VREDRPGDRRLVAYVVPEPGATVDTAELRAALRETLPDHMIPTAFVVLDALPLTLNGKLD 1377 Query: 516 RRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVV 575 R+ALPAP+Y SA RA P E++L ++ ++LGVE GVDD FFDLGGDSILS+Q+V Sbjct: 1378 RKALPAPDY-SARTSGRAARDPRERLLTALFGEILGVEPAGVDDGFFDLGGDSILSIQLV 1436 Query: 576 ARARAAGIQCRPRDIFVEQT--XXXXXXXXXXXXESHVVDEGV---GPVVATPIMRWLRE 630 ARARAAG+ RD+F QT + D V GP TP+M W Sbjct: 1437 ARARAAGLVLSVRDVFEHQTPALLARSAAAAPAGDRTARDSDVPADGPAPRTPMMGWFAA 1496 Query: 631 VDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEA 690 + FNQ+++ + P + D + L+A+LDRH LR+RV D+W++ +P Sbjct: 1497 LGSDLAAFNQSLVLRVPTALDPDTLDTALRAVLDRHDALRMRV------ADDWTIEIPPP 1550 Query: 691 GAVGARECLRTVDAL-TDDVLVE---------ARNRLDPAAGAMVSAVWVRETSQ----L 736 G+V +CL DA+ D+ V AR+RL PA G M+ AVWV + L Sbjct: 1551 GSVTPADCLVRFDAVGLDEAAVRSAVTEQARTARDRLAPADGRMLQAVWVDRGADRDGLL 1610 Query: 737 VLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVR 796 VL+ +HL VDGV+WRIL+ DL A+A G++ L GT + W+ L++ A Sbjct: 1611 VLVANHLVVDGVTWRILVPDLAAAYA----GET--LAPVGTPWRHWALSLSDLAGQPRTE 1664 Query: 797 DLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDIL 856 + D W +V + P DT+ TAG+++A LD +TT LL VP A V D+ Sbjct: 1665 EELDHWHSVLGDTPHTLRLDPARDTHATAGEITAELDADTTEALLTWVPGVCHATVNDVF 1724 Query: 857 LVAFGLA---WTEFLNR-SDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVE 912 L F LA W +D P+ +D+E HGR++E +LSRT GWFT+ YPV L Sbjct: 1725 LSTFALAVAGWRRGRGEDADAPVVLDLESHGRHEEAVPGAELSRTAGWFTSMYPVRLAP- 1783 Query: 913 NLPWEQVVAGDAALGGIVKAVKEQLRSLP-EGLTYGLLRYLNPEVDLGGSD---PTIGFN 968 +GD + +KAVKEQLR++P +GL YGLLR+LNP + P GFN Sbjct: 1784 ----PAGASGDGSALRALKAVKEQLRTVPGDGLGYGLLRHLNPRTRDALAALPLPEFGFN 1839 Query: 969 YLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASW 1028 YLGR+G + E W I+ MPL H V++NA +T +G LRA W Sbjct: 1840 YLGRIGQEGTD--EAPWTIEGGDVAGIDG----AMPLAHPVDVNAVARETADGTRLRARW 1893 Query: 1029 TWAPSAFDEEQATRLSRLWFEALAGICAHVR-GGGGGLTPSDVAPARLTQRQIDELSQRY 1087 T++ +A + E RL+ WF L + R G GGLTPSD+A L Q +I++L Sbjct: 1894 TYSRTALEPEDTQRLADTWFRLLRRLVEEARQPGAGGLTPSDIAHPALAQDEIEDLEHTV 1953 Query: 1088 -DVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHP 1146 + D+LPL P+Q+G LF + + DVY QL + G D R+R A ++ RH Sbjct: 1954 PGLQDILPLAPLQEGFLFLNLYDEN-ARDVYVGQLAFDLEGSFDGTRMRAAAGALLRRHA 2012 Query: 1147 NLAARFVE-QFGEPVQVLTADPMIAWRYLDL--RGDDLTPDHEIEQLCAAERSAVCDLLE 1203 NL A F + G VQV+ A+ WR DL R D+ D E +L A +R DL Sbjct: 2013 NLRAGFRQTATGTWVQVVPAELEPDWRECDLTDRADEAERDAEAGRLAAGDRERRFDLTS 2072 Query: 1204 RPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH----RLPAAAPYRN 1259 P R IR S ++ R V+T HHI++DGWS+P+L QE+ Y LP PYR+ Sbjct: 2073 PPLMRFTAIRLSADRVRLVMTNHHILLDGWSMPLLWQELTELYVSGGDPVSLPPVRPYRD 2132 Query: 1260 FVNWLXXXXXXXXXXXWREVLDGFETPTLVAP---PGVPGPRGIESYRVSAETTRALGEL 1316 + WL WR L G + TL+AP P P GI + + + T AL Sbjct: 2133 HLAWLAARDRDAARDAWRRSLSGLDEATLLAPDAGPAEAAPLGI-PFGLDRDATAALSAW 2191 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA 1376 AR + T+NTV+Q AW L + TG+ DV FG VSGRP +L G ESM+GL INT+P+RA Sbjct: 2192 ARGRGVTMNTVVQGAWALALAQATGRDDVVFGATVSGRPPELPGVESMIGLFINTLPVRA 2251 Query: 1377 KVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPI--DTSA 1434 ++ +GDL R+LQ+ L+H+ L DI H +GH +LFDT ++++YP+ DT++ Sbjct: 2252 RLDQAEPLGDLFRRLQNEQARLLDHQWPGLADIQHWAGHGELFDTAMVFQNYPVSADTTS 2311 Query: 1435 FMGVQELAVTEFNNREYNHYPLSVMALPGHE-LGLRVEYDTSVFDVSEIETLIDRFQRLL 1493 + L V ++ E + ++++A + L LR++Y + +L DR R+L Sbjct: 2312 -RQLDGLRVAGYDAVESTDFAVNLVAHTRDDALRLRLDYRADACAGDLVRSLADRMLRVL 2370 Query: 1494 EAMIDDPARRLSSMDVVDDDERTQ-LDEWANRAVLTQPVDSPQS-IPEVFARQVERDPEA 1551 EA++ D R ++ +D +D R + L EW P + P + + E+ + Q P+A Sbjct: 2371 EALVTDSDRPVAHLDTLDPAVRERVLVEWNG-----APTELPGTPLHELISGQARLTPDA 2425 Query: 1552 PAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAA 1611 AV +G +L Y ELD ANQLA L G VA+ + +S DA++++LAVLKTGAA Sbjct: 2426 VAVVCDGTTLTYAELDRRANQLARHLLGEGLGAEDFVAIALAKSLDAVISMLAVLKTGAA 2485 Query: 1612 YLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLT 1671 YLPIDP PA R+ +ML DA+P +T R+ G + V ++ + Sbjct: 2486 YLPIDPDYPAERITYMLDDARPALTLTEPVPVERYAGHSVTAVTDEERR----------S 2535 Query: 1672 P-SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHS-LVFDV 1729 P S AYMIYTSG+TG PKGV I H + L A G + HS L FD+ Sbjct: 2536 PWSARHAAYMIYTSGSTGRPKGVVIEHHALATYLHRARNTYTAMTGV--TVLHSPLAFDL 2593 Query: 1730 SVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTA 1789 ++ +W L GG + + + + L + TPS + +++ L TA Sbjct: 2594 TITALWTPLTAGGTVHLTSLEESDTQPSL-----------IKATPSHLPLLT--NLAATA 2640 Query: 1790 -----LVVAGEACPTEVVDRWAVDR---VMINAYGPTESTIYAAISAPLSPGSDVVPIGS 1841 L++ GEA T+ + W +INAYGPTEST+ VPIG Sbjct: 2641 SPSHTLILGGEALHTDHLATWRTQHPHVQIINAYGPTESTVNITDHRLDGTEEGPVPIGR 2700 Query: 1842 PVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGE-PGARM 1900 P +VLD LRPV PGV GELYLA LT RF A P PGARM Sbjct: 2701 PFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSSTPGARM 2760 Query: 1901 YRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPG 1960 YRTGDL W DG L Y GRAD Q+K+RG+RIE GEI+ L+ G+ QA V RED+PG Sbjct: 2761 YRTGDLAHWNHDGHLTYDGRADHQIKLRGHRIEPGEIETTLTAQTGITQATVQLREDQPG 2820 Query: 1961 DKRLVGYI-----TGTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPA 2015 D+RLV Y+ TG D R LT+ LP YMVP+A+VTL+ LPLT NGKLDR ALPA Sbjct: 2821 DQRLVAYLVVNDSTG-YDEKTVRDALTSALPDYMVPSALVTLDALPLTPNGKLDRTALPA 2879 Query: 2016 PEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTAL 2075 P Y ++ RAP T E+ L +FA VLGV+ A R+ + TAL Sbjct: 2880 PAYSASTAGRAPRTPREEVLCTLFAEVLGVDLVTIDDNFFDLGGHSLLATRLVSRTRTAL 2939 Query: 2076 DADLSVRTLFEAPTVAKLSLHVEHDAGERT 2105 +LS+R LFE PTVA L+ ++ RT Sbjct: 2940 GVELSIRQLFETPTVAGLAEALDASGTVRT 2969 Score = 635 bits (1638), Expect = e-179 Identities = 434/1146 (37%), Positives = 583/1146 (50%), Gaps = 114/1146 (9%) Query: 30 RAVLTDPGPTPV------TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVL 83 R L D G P+ T+P LFAEQ +R P A ALV G + +Y ELD +NRLA +L Sbjct: 4468 RRSLLDRGTGPLLEGLDATLPELFAEQALRTPGAPALVRGGTTVSYAELDLRTNRLARLL 4527 Query: 84 AEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAAL 143 + G +PG V L+ RS +++ L++ K G AY+P+ +P R+ +++D L Sbjct: 4528 RQQGVRPGTPVVMLMERSPAHVVATLAIAKAGGAYVPLHDTYPLDRMRHVVADTAATLIL 4587 Query: 144 TTADLRSRLDQYD--LAVIDMADPAIDRRPSDALSGP----------------------- 178 T +R Q + V+D A +DA G Sbjct: 4588 TDRAEVARAGQLGARVMVVDEFGAAPSGSEADAAPGTGTGTSTSTSTSTSTGSGSGSRSG 4647 Query: 179 ----------RPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQW 228 RP DLAY+ YTSG+TGVPK VAVTH V LV H P +V Sbjct: 4648 YVDDAPEVGLRPQDLAYVMYTSGSTGVPKGVAVTHRGVVDLVRD-HCWRPGVHERVLLHA 4706 Query: 229 HSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSP 288 FDVS +E+W L+ GG +VV P P + +L+ ++ + T +++ Sbjct: 4707 PH-AFDVSCYEMWVPLVSGGTVVVAPPG-HLDPAAITDLITAHGITAIHLTAGFFRVVAE 4764 Query: 289 EGLESTT----LIVAGEACPTELVDRWA---PGRVMINAYGPTEATIYAAMSEPLXXXXX 341 E E ++ G+ V R P V+ + YGPTE T+ E Sbjct: 4765 EAPECFAGVREVLTGGDVVSPAAVARVLAHHPRIVLRHLYGPTETTLCVTQHEVTAPYEA 4824 Query: 342 XXXXXXXXXXXXL--FVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPF 399 +VLD++L+P P GV GEL+++G G+A GY+ RPDLT RFVA P+ Sbjct: 4825 RGSLPVGRATGNTRAYVLDRYLQPVPAGVPGELFISGSGLARGYLDRPDLTCERFVADPY 4884 Query: 400 GETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVI 459 G +GERMYRTGDLVR+ + G+LEYL RAD+QVKIRG+R+ELGEI+A LA + QA V+ Sbjct: 4885 GGSGERMYRTGDLVRYNAAGELEYLARADDQVKIRGFRVELGEIEAVLATRPELAQAAVV 4944 Query: 460 AREDRPGDKRLVGYIT------GTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGK 513 REDRPGD+RLVGY+ G DP LR ++LP YMVP+A VVL T+PLT NGK Sbjct: 4945 VREDRPGDRRLVGYVVAAAGRDGEVDPDALRAFSRQALPDYMVPSAFVVLGTLPLTANGK 5004 Query: 514 LDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQ 573 LDR+ALPAP+Y AA+ RA TPAE++L ++A+VLG+ VGVDD FFDLGGDSILS+Q Sbjct: 5005 LDRKALPAPDY-GAASTGRAARTPAEELLCTLFAEVLGLSAVGVDDGFFDLGGDSILSIQ 5063 Query: 574 VVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVVDEG-----VGPVVATPIMRWL 628 +V+RARAAG+ RD+F Q+ ++ V E GP TP+M + Sbjct: 5064 LVSRARAAGLALAVRDVFEHQSTARLAAALTDRDDAASVPEAEAVPPYGPAPLTPVMARI 5123 Query: 629 REVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRV----------EDTQE 678 E+ FNQ+V+ P V D +V LQ +LD H LRLRV + Sbjct: 5124 AELGLGGDDFNQSVVVSLPPAVDRDRLVPALQRVLDHHDALRLRVLPDGSTEVRAPGSVP 5183 Query: 679 DTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ--- 735 D S++ GA GA DAL + AR+RL PA G M+ AV V T Sbjct: 5184 AADVLSVVTRAPGATGAAR-----DALLVEAACAARDRLAPAEGRMLQAVLVDGTDDTDG 5238 Query: 736 ----------LVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSAL 785 L+L+ HHL VD V+W I++ DL A+ + E GTS+ +W+ Sbjct: 5239 TGGTSGADGVLILVAHHLVVDSVTWSIVVPDLAAAY------RGEEPAPVGTSWRQWATS 5292 Query: 786 LAEHAKTDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVP 845 LA A V W + L + D AG++S L TT LL +P Sbjct: 5293 LARLATDPRVEAETAHWEHTLTGAGTL-RLDRGRDLQGDAGRISLDLAPHTTEALLTRLP 5351 Query: 846 AAFRAGVQDILLVAFGLA---WTEFLNRS-DTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 A V D+LL AF A W D P+ +D+E HGR++E +LSRT GWF Sbjct: 5352 GGVNASVHDVLLTAFAFAVAGWRRGRGEDPDAPVVLDLESHGRHEEAVPGAELSRTAGWF 5411 Query: 902 TTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLP-EGLTYGLLRYLNPEVD--- 957 T +PV L + W ++ AL +K VKEQLRS+P +GL +GLLR+LNP Sbjct: 5412 TALHPVRLAPDVTDWARLHQDGDALRDGLKQVKEQLRSVPGDGLGHGLLRHLNPTAGPRL 5471 Query: 958 LGGSDPTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTID 1017 +P GFNYLGR A + E W + P+ H VEL+A + Sbjct: 5472 ARLPEPDFGFNYLGRRVTPATG-TPEPWTV----TGGGLAASRPTAPMAHAVELSAVVHE 5526 Query: 1018 TDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHV-RGGGGGLTPSDVAPARLT 1076 +GP LRA WT+A + A RL+ WF AL + R G GGLTPSDV L+ Sbjct: 5527 GADGPRLRAEWTYARRLVPDHDARRLAEQWFRALEALVEQADRAGTGGLTPSDVTLGSLS 5586 Query: 1077 QRQIDE 1082 Q +I+E Sbjct: 5587 QSEIEE 5592 Score = 548 bits (1411), Expect = e-153 Identities = 397/1093 (36%), Positives = 529/1093 (48%), Gaps = 98/1093 (8%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+ QQ L F Y + + +TG LD LR A VV RH +L F Sbjct: 419 LPLSYAQQRLWFLHQLEGP--SPTYNITGALRLTGDLDPGALRAAFQDVVTRHESLRTVF 476 Query: 1153 VEQ-FGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAAL 1211 E G VL A A + +L D++ D +L A R DL RA L Sbjct: 477 SEDGHGARQTVLDA----AGVHFELPVADVSEDRLDARLEEAARHCF-DLTTDIPVRAEL 531 Query: 1212 IRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNWL 1264 R +H +L HHI DGWSL L++++ A Y R P AP Y +F W Sbjct: 532 FRLGAREHVLLLMVHHIAGDGWSLGPLIRDLAAAYTARAARRAPDWAPLPVQYADFALWQ 591 Query: 1265 XXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETT 1310 W+E L G E P P V RG V A Sbjct: 592 RAALGDAADATSPAGRQLAHWKEALAGLPDRLELPADRPLPAVASHRGGRVPLTVPAALH 651 Query: 1311 RALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLIN 1370 + ELAR T++ VLQAA LL RM DV GT V+GR D + +VG +N Sbjct: 652 SGVAELARESRTSVFMVLQAALAALLTRMGAGEDVPLGTPVAGRGDD--AVDQVVGFFVN 709 Query: 1371 TVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG------HEQLFDTLFL 1424 T+ +R + T LL +++ +H+ L + V H LF L Sbjct: 710 TLVLRTDTGGNPTFRALLDRVRDTDLTAYDHQDLPFEHLVDVLSPTRSLSHNPLFQVLLS 769 Query: 1425 YESYPIDTSAFMGVQELAVTEFN----------------NREYNHYPLSVMALPGHELGL 1468 ++ D A + L V N +R+ + P ++ Sbjct: 770 LDTTQQDALAALSATGLGVRLLNVTTGVAKLDLALEIAEHRDADGAPAGLVGA------- 822 Query: 1469 RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLT 1528 EY +FD + L++RF RLL+A++ DP+RR+ +DV+ ER + VLT Sbjct: 823 -AEYSADLFDEGTVTLLVERFLRLLDALVADPSRRIGDVDVLGPRERER--------VLT 873 Query: 1529 QPVDSPQS-IPEVFARQVERDP---------EAPAVTFEGESLNYGELDEAANQLANLLA 1578 + D+P+ + FA V R E G +L YGEL+E AN+LA L Sbjct: 874 EWNDTPRRPVQGTFADHVARHAAERPGHLAVETAGAAAPGGALTYGELNERANRLARALL 933 Query: 1579 VYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVT 1638 GA P + VA+ +PRSAD +++ LA K GAAYLP+DP+ PA R+ ++ DA P VT Sbjct: 934 ARGAGPERFVAVALPRSADLVLSALAAFKAGAAYLPVDPAHPAERITHLVSDAAPTLIVT 993 Query: 1639 TGDLRSRFDGFDLQVVEVDDPAV----------EIYPSTTLLTPSPDDIAYMIYTSGTTG 1688 T L + V+ +D P ++ + + P+ AYMIYTSGTTG Sbjct: 994 TSALAASLPDTGTPVLLLDTPETAATLAALPGHDVTDADRPVPLRPEHPAYMIYTSGTTG 1053 Query: 1689 VPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVP 1748 PKGV +TH + +LD + AGPG+ Q S FD S WE+ LL G LV+ P Sbjct: 1054 RPKGVVVTHTGLPGLLDIFTRDCAAGPGSRILQHLSPSFDASFWELAMGLLTGATLVVAP 1113 Query: 1749 ESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL-EGTALVVAGEACPTEVVDRWAV 1807 P+ L L L T S + ++ P+ L +G LVV EA P E+V+RW+ Sbjct: 1114 PETTPGPE-LAELATRHAATHLSLTTSVLGLLPPDSLPDGLTLVVGAEAIPPELVERWSP 1172 Query: 1808 DRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELY 1867 R M+N+YGPTE+T+ + +S PLS G V PIGSPV A +VLD LRPVPPGV GELY Sbjct: 1173 GRTMLNSYGPTETTVCSTMSGPLS-GPAVPPIGSPVANSAVYVLDAALRPVPPGVPGELY 1231 Query: 1868 LAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKI 1927 A LT RFVA PFGEPG+R+YRTGDLVRW DGQL+YLGRAD QVKI Sbjct: 1232 AAGAHLARGYHDRRALTAERFVANPFGEPGSRLYRTGDLVRWRPDGQLEYLGRADTQVKI 1291 Query: 1928 RGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTN 1983 RG RIE EI+A +++ + +A VI REDRPGD+RLV Y+ T D A R+ L Sbjct: 1292 RGLRIEPTEIEAVITERPHLARAAVIVREDRPGDRRLVAYVVPEPGATVDTAELRAALRE 1351 Query: 1984 RLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVL 2043 LP +M+P A V L+ LPLT+NGKLDR+ALPAP+Y + RA E+ L +F +L Sbjct: 1352 TLPDHMIPTAFVVLDALPLTLNGKLDRKALPAPDYSARTSGRAARDPRERLLTALFGEIL 1411 Query: 2044 GVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLH-VEHDAG 2102 GVE ++++ A A LSVR +FE T A L+ AG Sbjct: 1412 GVEPAGVDDGFFDLGGDSILSIQLVARARAA-GLVLSVRDVFEHQTPALLARSAAAAPAG 1470 Query: 2103 ERTDRVSFAAVHG 2115 +RT R S G Sbjct: 1471 DRTARDSDVPADG 1483 Score = 453 bits (1165), Expect = e-124 Identities = 356/1055 (33%), Positives = 481/1055 (45%), Gaps = 90/1055 (8%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ QQ L F Y L + + G LD LR A+ VVARH +L F Sbjct: 2980 IPLSYAQQRLWFLHQLEGPSA--TYNTVLTLRLGGALDVDALRAAIGDVVARHESLRTVF 3037 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALI 1212 E Q++ + + + + EI DL + R +L Sbjct: 3038 TEDERGAYQIVLPVEAASTPFTVVD----VAEEEIGDRLDEAVGHCFDLAQELPARTSLF 3093 Query: 1213 RTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHR-------LPAAAPYRNFVNWLX 1265 R S +H +L HHI D WS L Q++ A Y P Y ++ W Sbjct: 3094 RVSEREHVLLLLIHHIASDAWSRAPLAQDLTAAYAARVRSEAPMWAPVTVQYADYALWQQ 3153 Query: 1266 XXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTR 1311 W++ L G + PT P V G G + V E Sbjct: 3154 EILGDDTDADSLAGRQLAYWKQQLAGLPEQLDLPTDRPRPAVAGYSGDRVPFTVPTELHT 3213 Query: 1312 ALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINT 1371 L ELAR+ +T+ V+QAA LL R+ D+ GT V+GR D A+ ++GL INT Sbjct: 3214 RLTELARATNTSAFMVIQAAVAVLLTRLGAGEDIPIGTPVAGRTDD--AADDLIGLFINT 3271 Query: 1372 VPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHL-------ALNDIHHVSGHEQLFDTLFL 1424 + +R S D T LL +++ H+ L ALN +S H LF L Sbjct: 3272 LVLRTDTSGDPTFRRLLDRVRDTDLAAYAHQDLPFERLVEALNPARTLS-HHPLFQVLLT 3330 Query: 1425 YESYPIDTSAFMGVQELAVTEFNNREYNH----YPLSVMALPGHELGLR-------VEYD 1473 + + + A + EL RE + LS + R +++ Sbjct: 3331 FNNTDHE-GALKDISELPGLTVALREVQRTSSKFDLSFGFAESFDTSRRPQGIEAALDFS 3389 Query: 1474 TSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQ-LDEWANRAVLTQPVD 1532 T + D + + DRF R+LEA+ P R + +++++D ER + L EW P + Sbjct: 3390 TELLDRRSAQAIADRFLRVLEAVTTAPDRPIGAVELMDPAERERILVEWNGA-----PTE 3444 Query: 1533 SPQS-IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALM 1591 P + + E+ + Q P+A AV +G SL Y ELD ANQLA L G VA+ Sbjct: 3445 LPGTPLHELISEQARLTPDAVAVVCDGTSLTYAELDGRANQLARHLLEQGLGAEDFVAIA 3504 Query: 1592 VPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDL 1651 + +S DA+ ++LAVLK GAAYLPIDP PA R+ +ML DA+P +T + +D Sbjct: 3505 LHKSLDAVTSMLAVLKAGAAYLPIDPDYPAERITYMLDDAQPALTLTAPIPPASYDS--- 3561 Query: 1652 QVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAEL 1711 P EI S AYMIYTSG+TG PKGV I H + L Sbjct: 3562 ------RPTSEITDVERRSPWSARHAAYMIYTSGSTGRPKGVVIEHHALATYLHRARNTY 3615 Query: 1712 PAGPGAVWSQWHS-LVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVL 1770 A G + HS L FD+++ +W L GG + + A L + Sbjct: 3616 TAMTGV--TVLHSPLAFDLTITALWTPLTAGGTVHLTSLEEAEVQPSL-----------I 3662 Query: 1771 YQTPSAVRMMS--PEGLEGT-ALVVAGEACPTEVVDRWAVDRV---MINAYGPTESTIYA 1824 TPS + +++ PE + L++ GEA T+ + W +INAYGPTEST+ Sbjct: 3663 KATPSHLPLLTTLPETASPSYTLILGGEALHTDHLATWRTQHPGVQIINAYGPTESTVNI 3722 Query: 1825 AISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLT 1884 VPIG P +VLD LRPV PGV GELYLA LT Sbjct: 3723 TDHRLDGTEEGSVPIGRPFANTQVYVLDSALRPVAPGVTGELYLAGEQLARGYLGRSALT 3782 Query: 1885 GTRFVACPFGE-PGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSD 1943 RF A P PGARMYRTGDL W G L Y GRAD Q+K+RG+RIE GEI+ L+ Sbjct: 3783 AERFTANPHSSVPGARMYRTGDLAHWNHHGHLTYDGRADHQIKLRGHRIEPGEIETTLTA 3842 Query: 1944 VDGVDQAVVIAREDRPGDKRLVGYI----TGTADPAAARSELTNRLPAYMVPAAVVTLET 1999 G+ QA + RED PGD+RLV Y+ + D R L + LP YM P+A VTL+ Sbjct: 3843 QPGITQATIQLREDTPGDQRLVAYLVVNDSTEYDEPTLRDALASALPDYMRPSAYVTLDA 3902 Query: 2000 LPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXX 2059 LPLT NGKLDR ALPAP Y ++ RAP T E+ L +FA VLGV+ Sbjct: 3903 LPLTPNGKLDRTALPAPAYSASTAGRAPRTPREEILCTLFAEVLGVDLVTIDDNFFDLGG 3962 Query: 2060 XXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 A R+ + TAL +LSVR FE PT+A LS Sbjct: 3963 HSLLATRLVSRARTALGVELSVRQFFETPTIAGLS 3997 Score = 450 bits (1157), Expect = e-123 Identities = 357/1114 (32%), Positives = 529/1114 (47%), Gaps = 123/1114 (11%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ QQ L F Y + + +TG LD L A++ ++ARH +L + Sbjct: 4019 IPLSYAQQRLWFLHQLEGPSA--TYNIPTTLRLTGTLDTGALHAALNDLLARHESLRTTY 4076 Query: 1153 VEQFGEPVQVLTA-DP-MIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 E P QV+ A +P M+ +D T + E++ + +A DL RA Sbjct: 4077 TEDDEGPRQVIHAWEPGMLPLGVVD------TGEGELDAMLSAGVHHAFDLTAGIPVRAT 4130 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNW 1263 L R S +H +L HHI D WS L ++ A Y +PA P Y ++ W Sbjct: 4131 LFRISEQEHVLLLLIHHIATDAWSRTPLGHDLAAAYAARCAGDVPAWEPLPVQYADYALW 4190 Query: 1264 LXXXXXXXXXXX---------WREVL----DGFETPTLVAPPGVPGPRGIE-SYRVSAET 1309 W L + + PT P V G ++ + A+ Sbjct: 4191 QREVLGDEGDADAPAGRQLAYWTRQLADLPEQLDLPTDRPRPAVASQDGDRVAFSLDADL 4250 Query: 1310 TRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLI 1369 L ELAR+ H++ V+QAA LL R+ D+ GT V+GR D E++VG + Sbjct: 4251 YVRLTELARATHSSTFMVVQAALAVLLTRLGAGEDIPIGTPVAGRTDD--ATENLVGFFV 4308 Query: 1370 NTVPIRAKVSADTTVGDLLRQ-----LQSHHNDTLEHEHL--ALNDIHHVSGHEQLFDTL 1422 NT+ +R S + T +LL + L ++ + L E L ALN ++ H LF + Sbjct: 4309 NTLVLRNDTSGNPTFRELLEETRRTDLAAYAHQDLPFERLVEALNPARTLA-HHPLFQVM 4367 Query: 1423 FLYESYPIDTSAFMGVQELAVTEFNNR------EYNHYPLSVMALPGHELGLR--VEYDT 1474 + + D A + + L V +R + V G GL +++ T Sbjct: 4368 LILSTAETDPDASLALPGLRVGAERSRLGAAKVDLAFALAEVRDGEGRSTGLTGALDFRT 4427 Query: 1475 SVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSP 1534 +FD S +L++RF R LEA++ DP RLS + V+ ER L + +L + +D+ Sbjct: 4428 DLFDRSTARSLVERFVRTLEAVVADPGVRLSRVPVLSGSERRSLLDRGTGPLL-EGLDA- 4485 Query: 1535 QSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPR 1594 ++PE+FA Q R P APA+ G +++Y ELD N+LA LL G PG V +++ R Sbjct: 4486 -TLPELFAEQALRTPGAPALVRGGTTVSYAELDLRTNRLARLLRQQGVRPGTPVVMLMER 4544 Query: 1595 SADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVV 1654 S +VA LA+ K G AY+P+ + P R+ ++ D +T +R +V+ Sbjct: 4545 SPAHVVATLAIAKAGGAYVPLHDTYPLDRMRHVVADTAATLILTDRAEVARAGQLGARVM 4604 Query: 1655 EVDD-------------PAVEIYPSTTLLTPS----------------------PDDIAY 1679 VD+ P ST+ T + P D+AY Sbjct: 4605 VVDEFGAAPSGSEADAAPGTGTGTSTSTSTSTSTGSGSGSRSGYVDDAPEVGLRPQDLAY 4664 Query: 1680 MIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALL 1739 ++YTSG+TGVPKGVA+TH V ++ + H+ FDVS +E+W L+ Sbjct: 4665 VMYTSGSTGVPKGVAVTHRGVVDLVRDHCWRPGVHERVLLHAPHA--FDVSCYEMWVPLV 4722 Query: 1740 HGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS---PEGLEGTALVVAGEA 1796 GG +V+ P P + L+ + G+ ++ T R+++ PE G V+ G Sbjct: 4723 SGGTVVVAPPGHL-DPAAITDLITAHGITAIHLTAGFFRVVAEEAPECFAGVREVLTGG- 4780 Query: 1797 CPTEVVDRWAVDRVMIN--------AYGPTESTIYAA---ISAPLSPGSDVVPIGSPVPK 1845 +VV AV RV+ + YGPTE+T+ ++AP + P+G Sbjct: 4781 ---DVVSPAAVARVLAHHPRIVLRHLYGPTETTLCVTQHEVTAPYEARGSL-PVGRATGN 4836 Query: 1846 GATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGD 1905 +VLD +L+PVP GV GEL+++ LT RFVA P+G G RMYRTGD Sbjct: 4837 TRAYVLDRYLQPVPAGVPGELFISGSGLARGYLDRPDLTCERFVADPYGGSGERMYRTGD 4896 Query: 1906 LVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLV 1965 LVR+ G+L+YL RAD+QVKIRG+R+ELGEI+A L+ + QA V+ REDRPGD+RLV Sbjct: 4897 LVRYNAAGELEYLARADDQVKIRGFRVELGEIEAVLATRPELAQAAVVVREDRPGDRRLV 4956 Query: 1966 GYIT------GTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ 2019 GY+ G DP A R+ LP YMVP+A V L TLPLT NGKLDR+ALPAP+Y Sbjct: 4957 GYVVAAAGRDGEVDPDALRAFSRQALPDYMVPSAFVVLGTLPLTANGKLDRKALPAPDYG 5016 Query: 2020 SAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADL 2079 +A RA T E+ L +FA VLG+ ++++ + A L Sbjct: 5017 AASTGRAARTPAEELLCTLFAEVLGLSAVGVDDGFFDLGGDSILSIQLVSRARAA-GLAL 5075 Query: 2080 SVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAAV 2113 +VR +FE + A+L A TDR A+V Sbjct: 5076 AVRDVFEHQSTARL-------AAALTDRDDAASV 5102 Score = 403 bits (1036), Expect = e-109 Identities = 321/914 (35%), Positives = 436/914 (47%), Gaps = 77/914 (8%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R + + +L+D E ++I V N A PG TP + L +EQ PDAVA+V S Sbjct: 3418 RPIGAVELMDPAERERILVEWNGAPTELPG-TP--LHELISEQARLTPDAVAVVCDGTSL 3474 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 TY ELD +N+LA L E G VA + +S +A+ S+L+VLK GAAYLP+DP +P Sbjct: 3475 TYAELDGRANQLARHLLEQGLGAEDFVAIALHKSLDAVTSMLAVLKAGAAYLPIDPDYPA 3534 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMT 187 RI +M+ DA+P LT + D + I + R P A AYM Sbjct: 3535 ERITYMLDDAQPALTLTAPIPPASYDSRPTSEITDVER---RSPWSARHA------AYMI 3585 Query: 188 YTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHS-LVFDVSVWEIWGALLH 246 YTSG+TG PK V + HH + + + G + HS L FD+++ +W L Sbjct: 3586 YTSGSTGRPKGVVIEHHALATYLHRARNTYTAMTGV--TVLHSPLAFDLTITALWTPLTA 3643 Query: 247 GGRLVVVP-ESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLS--PEGLE-STTLIVAGEA 302 GG + + E P S++ TPS +L+ PE S TLI+ GEA Sbjct: 3644 GGTVHLTSLEEAEVQP------------SLIKATPSHLPLLTTLPETASPSYTLILGGEA 3691 Query: 303 CPTELVDRWA---PGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 T+ + W PG +INAYGPTE+T+ ++VLD Sbjct: 3692 LHTDHLATWRTQHPGVQIINAYGPTESTVNITDHRLDGTEEGSVPIGRPFANTQVYVLDS 3751 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGET-GERMYRTGDLVRWGSD 418 LRP GV GELY+AG +A GY+GR LTA RF A P G RMYRTGDL W Sbjct: 3752 ALRPVAPGVTGELYLAGEQLARGYLGRSALTAERFTANPHSSVPGARMYRTGDLAHWNHH 3811 Query: 419 GQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYI---- 474 G L Y GRAD Q+K+RG+RIE GEI+ L G+ QA + RED PGD+RLV Y+ Sbjct: 3812 GHLTYDGRADHQIKLRGHRIEPGEIETTLTAQPGITQATIQLREDTPGDQRLVAYLVVND 3871 Query: 475 TGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAP 534 + D LR ALA +LP YM P+A V LD +PLT NGKLDR ALPAP Y SA+ RAP Sbjct: 3872 STEYDEPTLRDALASALPDYMRPSAYVTLDALPLTPNGKLDRTALPAPAY-SASTAGRAP 3930 Query: 535 STPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVE 593 TP E+IL ++A+VLGV+ V +DD+FFDLGG S+L+ ++V+RAR A G++ R F Sbjct: 3931 RTPREEILCTLFAEVLGVDLVTIDDNFFDLGGHSLLATRLVSRARTALGVELSVRQFFET 3990 Query: 594 QTXXXXXXXXXXXXESHVV------DEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAP 647 T + E + A + +L +++GP+ +N + Sbjct: 3991 PTIAGLSGAFDRAGRARAALTARPRPERIPLSYAQQRLWFLHQLEGPSATYNIPTTLRLT 4050 Query: 648 AGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDE----WSLLVPEAGAVGARECLRTVD 703 + + L LL RH +LR + E + W + G V E +D Sbjct: 4051 GTLDTGALHAALNDLLARHESLRTTYTEDDEGPRQVIHAWEPGMLPLGVVDTGE--GELD 4108 Query: 704 ALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIA 760 A+ + + D AG V A R + Q L+L+IHH+A D S L DL A Sbjct: 4109 AM---LSAGVHHAFDLTAGIPVRATLFRISEQEHVLLLLIHHIATDAWSRTPLGHDLAAA 4165 Query: 761 WAQHCTGQS---IELPAGGTSFARWS-ALLAEHAKTDTV--RDLADAWRAVTSVPQALP- 813 +A C G LP +A W +L + D R LA R + +P+ L Sbjct: 4166 YAARCAGDVPAWEPLPVQYADYALWQREVLGDEGDADAPAGRQLAYWTRQLADLPEQLDL 4225 Query: 814 ------PVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEF 867 P D A L A L V T E+ A + ++ A + T Sbjct: 4226 PTDRPRPAVASQDGDRVAFSLDADLYVRLT-----ELARATHSSTFMVVQAALAVLLTRL 4280 Query: 868 LNRSDTPIGVDVEG 881 D PIG V G Sbjct: 4281 GAGEDIPIGTPVAG 4294 Score = 402 bits (1033), Expect = e-109 Identities = 321/927 (34%), Positives = 450/927 (48%), Gaps = 79/927 (8%) Query: 6 STRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDR 65 S R + D LD +++ V N A PG TP + L + Q PDAVA+V Sbjct: 2377 SDRPVAHLDTLDPAVRERVLVEWNGAPTELPG-TP--LHELISGQARLTPDAVAVVCDGT 2433 Query: 66 SWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAH 125 + TY ELD +N+LA L G VA + +S +A++S+L+VLKTGAAYLP+DP + Sbjct: 2434 TLTYAELDRRANQLARHLLGEGLGAEDFVAIALAKSLDAVISMLAVLKTGAAYLPIDPDY 2493 Query: 126 PDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAY 185 P RI +M+ DA+P LT R + + + + R P A AY Sbjct: 2494 PAERITYMLDDARPALTLTEPVPVERYAGHSVTAVTDEER---RSPWSARHA------AY 2544 Query: 186 MTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHS-LVFDVSVWEIWGAL 244 M YTSG+TG PK V + HH + + + G + HS L FD+++ +W L Sbjct: 2545 MIYTSGSTGRPKGVVIEHHALATYLHRARNTYTAMTGV--TVLHSPLAFDLTITALWTPL 2602 Query: 245 LHGG--RLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAGEA 302 GG L + ES D LI S L + A SP S TLI+ GEA Sbjct: 2603 TAGGTVHLTSLEES------DTQPSLIKATPSHLPLLTNLAATASP----SHTLILGGEA 2652 Query: 303 CPTELVDRWA---PGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDK 359 T+ + W P +INAYGPTE+T+ ++VLD Sbjct: 2653 LHTDHLATWRTQHPHVQIINAYGPTESTVNITDHRLDGTEEGPVPIGRPFANTQVYVLDS 2712 Query: 360 WLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGET-GERMYRTGDLVRWGSD 418 LRP GV GELY+AG +A GY+GRP LTA RF A P T G RMYRTGDL W D Sbjct: 2713 ALRPVAPGVTGELYLAGEQLARGYLGRPALTAERFTANPHSSTPGARMYRTGDLAHWNHD 2772 Query: 419 GQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYI---- 474 G L Y GRAD Q+K+RG+RIE GEI+ L G+ QA V RED+PGD+RLV Y+ Sbjct: 2773 GHLTYDGRADHQIKLRGHRIEPGEIETTLTAQTGITQATVQLREDQPGDQRLVAYLVVND 2832 Query: 475 -TGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRA 533 TG D +R AL +LP YMVP+A+V LD +PLT NGKLDR ALPAP Y SA+ RA Sbjct: 2833 STGY-DEKTVRDALTSALPDYMVPSALVTLDALPLTPNGKLDRTALPAPAY-SASTAGRA 2890 Query: 534 PSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFV 592 P TP E++L ++A+VLGV+ V +DD+FFDLGG S+L+ ++V+R R A G++ R +F Sbjct: 2891 PRTPREEVLCTLFAEVLGVDLVTIDDNFFDLGGHSLLATRLVSRTRTALGVELSIRQLFE 2950 Query: 593 EQTXXXXXXXXXXXXESHVV------DEGVGPVVATPIMRWLREVDGPTGQFNQTVITQA 646 T E + A + +L +++GP+ +N TV+T Sbjct: 2951 TPTVAGLAEALDASGTVRTALTARPRPERIPLSYAQQRLWFLHQLEGPSATYN-TVLTLR 3009 Query: 647 PAGVTEDDVV-VILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDAL 705 G + D + + ++ RH +LR T+++ + +++P E T + Sbjct: 3010 LGGALDVDALRAAIGDVVARHESLRTVF--TEDERGAYQIVLPV-------EAASTPFTV 3060 Query: 706 TDDVLVEARNRLDPAAG----------AMVSAVWVRETSQ-LVLMIHHLAVDGVSWRILL 754 D E +RLD A G A S V E L+L+IHH+A D S L Sbjct: 3061 VDVAEEEIGDRLDEAVGHCFDLAQELPARTSLFRVSEREHVLLLLIHHIASDAWSRAPLA 3120 Query: 755 EDLNIAWAQHCTGQS---IELPAGGTSFARW-SALLAEHAKTDTV--RDLADAWRAVTSV 808 +DL A+A ++ + +A W +L + D++ R LA + + + Sbjct: 3121 QDLTAAYAARVRSEAPMWAPVTVQYADYALWQQEILGDDTDADSLAGRQLAYWKQQLAGL 3180 Query: 809 PQALPPVQPDTDTYVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVAFGLAWT 865 P+ L + D AG + +L L E+ A ++ A + T Sbjct: 3181 PEQL-DLPTDRPRPAVAGYSGDRVPFTVPTELHTRLTELARATNTSAFMVIQAAVAVLLT 3239 Query: 866 EFLNRSDTPIGVDVEGHGRYDELASDV 892 D PIG V GR D+ A D+ Sbjct: 3240 RLGAGEDIPIGTPVA--GRTDDAADDL 3264 Score = 320 bits (821), Expect = 1e-84 Identities = 253/713 (35%), Positives = 337/713 (47%), Gaps = 71/713 (9%) Query: 239 EIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLS------PEGLE 292 E+WG LLHGGRLVVVP V P LL E+V+VL QTPSA L+ P L Sbjct: 16 ELWGPLLHGGRLVVVPHDVTRDPAAFLALLARERVTVLNQTPSAFHQLAAADRENPTELA 75 Query: 293 STTLIVAGEACPTELVDRW-------APGRVMINAYGPTEATIYA---AMSEPLXXXXXX 342 T++ GEA + W AP ++N YG TE T++ A+ Sbjct: 76 LRTVVFGGEALDLSRLADWYERHAEDAPA--LVNMYGITETTVHVSHFALDRATAAASSA 133 Query: 343 XXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACP---- 398 ++VLD LRP GV GE+YVAG G+A GY+GRP LTA RF A P Sbjct: 134 STIGVNIPDLRVYVLDDRLRPTAPGVTGEMYVAGAGLARGYLGRPALTADRFPADPYAAL 193 Query: 399 FGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVV 458 FGE G RMYRTGDL R +DG L+YLGRAD+QVKIRG+RIE GEI+A LA VD V Sbjct: 194 FGERGTRMYRTGDLARRRTDGGLDYLGRADQQVKIRGFRIEPGEIEAVLAAHPAVDDVAV 253 Query: 459 IAREDRPGDKRLVGY-ITGTADPAQ-LRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDR 516 +ARED GD RLV Y +TG+ A+ L A LP +M+P+A V LD +PLT NGKLD Sbjct: 254 VAREDVQGDPRLVAYVVTGSGATARALHDHAAGHLPDHMLPSAFVTLDVLPLTPNGKLDT 313 Query: 517 RALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 576 +ALPAP + RAP P E+IL ++A+VLGV R+ VDDSFFDLGG S+L+ ++ Sbjct: 314 KALPAPAHAGQVTG-RAPRGPREEILCALFAEVLGVPRLTVDDSFFDLGGHSLLATRLAG 372 Query: 577 RARAA-GIQCRPRDIFVEQTXXXXXXXXXXXXESHVVDEGVGPVV-----------ATPI 624 R R G++ R +F T S G GP A Sbjct: 373 RIRGTLGVELSVRRLFETPTVAGLSAALDGAERS-----GTGPTAGERPERLPLSYAQQR 427 Query: 625 MRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWS 684 + +L +++GP+ +N T + + + Q ++ RH +LR + + Sbjct: 428 LWFLHQLEGPSPTYNITGALRLTGDLDPGALRAAFQDVVTRHESLRTVFSEDGHGARQTV 487 Query: 685 LLVPEAGAVGARECLRTVDALTD--DVLVE--ARNRLDPAAGAMVSAVWVRETSQ---LV 737 L A G L D D D +E AR+ D V A R ++ L+ Sbjct: 488 L-----DAAGVHFELPVADVSEDRLDARLEEAARHCFDLTTDIPVRAELFRLGAREHVLL 542 Query: 738 LMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFARWSALL---AEHAK 791 LM+HH+A DG S L+ DL A+ ++ + LP FA W A A Sbjct: 543 LMVHHIAGDGWSLGPLIRDLAAAYTARAARRAPDWAPLPVQYADFALWQRAALGDAADAT 602 Query: 792 TDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL---LGEVPAAF 848 + R LA A+ +P L + D A + + L + E+ Sbjct: 603 SPAGRQLAHWKEALAGLPDRL-ELPADRPLPAVASHRGGRVPLTVPAALHSGVAELARES 661 Query: 849 RAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 R V +L A T D P+G V G G D + + VG+F Sbjct: 662 RTSVFMVLQAALAALLTRMGAGEDVPLGTPVAGRG-------DDAVDQVVGFF 707 Score = 267 bits (682), Expect = 2e-68 Identities = 173/404 (42%), Positives = 214/404 (52%), Gaps = 28/404 (6%) Query: 1733 EIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS------PEGLE 1786 E+WG LLHGGRLV+VP + P ALL E V VL QTPSA ++ P L Sbjct: 16 ELWGPLLHGGRLVVVPHDVTRDPAAFLALLARERVTVLNQTPSAFHQLAAADRENPTELA 75 Query: 1787 GTALVVAGEACPTEVVDRW----AVDR-VMINAYGPTESTIYA---AISAPLSPGSDVVP 1838 +V GEA + W A D ++N YG TE+T++ A+ + S Sbjct: 76 LRTVVFGGEALDLSRLADWYERHAEDAPALVNMYGITETTVHVSHFALDRATAAASSAST 135 Query: 1839 IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACP----FG 1894 IG +P +VLD+ LRP PGV GE+Y+A LT RF A P FG Sbjct: 136 IGVNIPDLRVYVLDDRLRPTAPGVTGEMYVAGAGLARGYLGRPALTADRFPADPYAALFG 195 Query: 1895 EPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIA 1954 E G RMYRTGDL R DG L YLGRAD+QVKIRG+RIE GEI+A L+ VD V+A Sbjct: 196 ERGTRMYRTGDLARRRTDGGLDYLGRADQQVKIRGFRIEPGEIEAVLAAHPAVDDVAVVA 255 Query: 1955 REDRPGDKRLVGY-ITGT-ADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRA 2012 RED GD RLV Y +TG+ A A LP +M+P+A VTL+ LPLT NGKLD +A Sbjct: 256 REDVQGDPRLVAYVVTGSGATARALHDHAAGHLPDHMLPSAFVTLDVLPLTPNGKLDTKA 315 Query: 2013 LPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVN 2072 LPAP + RAP E+ L +FA VLGV R A R+ + Sbjct: 316 LPAPAHAGQVTGRAPRGPREEILCALFAEVLGVPRLTVDDSFFDLGGHSLLATRLAGRIR 375 Query: 2073 TALDADLSVRTLFEAPTVAKLSLHVE--------HDAGERTDRV 2108 L +LSVR LFE PTVA LS ++ AGER +R+ Sbjct: 376 GTLGVELSVRRLFETPTVAGLSAALDGAERSGTGPTAGERPERL 419 Score = 43.5 bits (101), Expect = 0.44 Identities = 71/311 (22%), Positives = 112/311 (36%), Gaps = 40/311 (12%) Query: 1054 ICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDV-----------LPLTPVQQGL 1102 + + R G L DV + T R L+ R D V PLTPV + Sbjct: 5064 LVSRARAAGLALAVRDVFEHQSTARLAAALTDRDDAASVPEAEAVPPYGPAPLTPVMARI 5123 Query: 1103 LFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQV 1162 G+G D + + +++ +D+ RL A+ V+ H L R + V+ Sbjct: 5124 A-----ELGLGGDDFNQSVVVSLPPAVDRDRLVPALQRVLDHHDALRLRVLPDGSTEVRA 5178 Query: 1163 LTADPMIAWRYLDLRGDDLTPDHE----IEQLCAA-ERSAVCDLLERPTFRAALIR---- 1213 + P + R T +E CAA +R A E +A L+ Sbjct: 5179 PGSVPAADVLSVVTRAPGATGAARDALLVEAACAARDRLAPA---EGRMLQAVLVDGTDD 5235 Query: 1214 ------TSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHR-LPAAAPYRNFVNWL-- 1264 TSG +L HH+V+D + I++ ++ A Y G P +R + L Sbjct: 5236 TDGTGGTSGADGVLILVAHHLVVDSVTWSIVVPDLAAAYRGEEPAPVGTSWRQWATSLAR 5295 Query: 1265 --XXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAETTRA-LGELARSQH 1321 W L G T L + G G S ++ TT A L L + Sbjct: 5296 LATDPRVEAETAHWEHTLTGAGTLRLDRGRDLQGDAGRISLDLAPHTTEALLTRLPGGVN 5355 Query: 1322 TTINTVLQAAW 1332 +++ VL A+ Sbjct: 5356 ASVHDVLLTAF 5366 >tr|Q0S6F2|Q0S6F2_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal peptide synthetase; EC=5.1.1.11; EC=6.1.1.13;[Rhodococcus sp.] Length = 6278 Score = 1338 bits (3464), Expect = 0.0 Identities = 857/2180 (39%), Positives = 1189/2180 (54%), Gaps = 112/2180 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +T +P+T + D+L E + + +R P P+++ F V A DAVA+ Sbjct: 2803 VTTDPAT-PVGDIDILHAPERELVLTAAHRPGTDVP---PLSLVDAFDRMVASAGDAVAV 2858 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 S TYR LD+ +NRLA +L G V + RS + ++++L+V+KTGA YLP Sbjct: 2859 RCDGASMTYRALDDRANRLARLLVAQGVGAETLVVVGMTRSIDLVVALLAVVKTGAGYLP 2918 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRP 180 VD A P R+ F++ DA+P LTT + V+ + DP S P Sbjct: 2919 VDVASPAERLAFVLGDARPECVLTTTADAGTFRGAGVPVVVLDDPETVTALQQFSSLPVT 2978 Query: 181 DD----------LAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHS 230 DD +AY+ YTSG+TG PK V V+H NV L++ GP VW+ +HS Sbjct: 2979 DDDRRTPLHLDSVAYVIYTSGSTGQPKGVQVSHRNVITLLANTQTLFGFGPADVWTMFHS 3038 Query: 231 LVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPE- 289 FD SVWE+WGAL HGGRLV+V SP+ LL E V+V+ QTP+A L+ Sbjct: 3039 AAFDFSVWEMWGALAHGGRLVLVDYFTARSPERFLELLRGETVTVVNQTPTAFYQLAEAD 3098 Query: 290 ------GLESTTLIVAGEACPTELVDRWAPGR-----VMINAYGPTEATIYAA---MSEP 335 GL +I GEA + RW R V++N YG TE T++ + + Sbjct: 3099 RLAGGPGLSLRYVIFGGEALEFGQLRRWYARRGDAAPVLVNMYGITETTVHVSHLPIHRD 3158 Query: 336 LXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFV 395 L ++VLD L P P GVVGE+YV+G V+ GY+GR LT+ RFV Sbjct: 3159 LVEEESASVIGRGLPGLRVYVLDGRLHPVPPGVVGEMYVSGAQVSRGYLGRAALTSGRFV 3218 Query: 396 ACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQ 455 A PF G RMYR+GDL RW GQLEYLGR D QV+++GYRIELGE++AAL +GV Q Sbjct: 3219 ADPF-TPGARMYRSGDLGRWNGHGQLEYLGRNDLQVQVKGYRIELGEVEAALLACEGVAQ 3277 Query: 456 AVVIAREDRPGDKRLVGYI---TGTA-DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVN 511 +VV AR DR LVGY+ TG A DPA + A A L ++MVP AVVVLD +P TVN Sbjct: 3278 SVVTARGDR-----LVGYVVPETGAAIDPAAIIDAAAVRLASHMVPAAVVVLDELPRTVN 3332 Query: 512 GKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILS 571 GKLDR+ALP P++ R P T E+ILAD++A+VLG++ VGVDDSFF LGGDSI+S Sbjct: 3333 GKLDRKALPEPDFGQRVTAGRGPVTETERILADLFAEVLGLDSVGVDDSFFTLGGDSIMS 3392 Query: 572 MQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVVDE----GVGPVVATPIMRW 627 +Q+V RA+ AGI PR++F +T + V+DE G+G + TPI+RW Sbjct: 3393 IQLVTRAKGAGILISPREVFERKTVAGLAAAAGTEDGTVVLDELPGGGIGEIPLTPIVRW 3452 Query: 628 LREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLV 687 + G +++Q+ + PA V E + LQA+LDRH LR R+ T + WS+ V Sbjct: 3453 MLARGGDFRRYSQSALFTLPATVDERTLTEALQAVLDRHELLRARLYRTSRTEEGWSMEV 3512 Query: 688 PEAGAVGARECLRTVDALTDDV---LVEARNRLDPAAGAMVSAVWV---RETSQLVLMIH 741 G+V A LR DDV L A +RLDP +G M+ AVW+ +++++++H Sbjct: 3513 QAEGSVRATTVLRR--GRMDDVGAELDSALHRLDPESGVMMQAVWLDRAEHPARVLIVVH 3570 Query: 742 HLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADA 801 HL DGVSWRIL+ DL A AQ +G + L GTS RW+ LA+ A+ + Sbjct: 3571 HLVTDGVSWRILIPDLAAACAQLQSGAAPALEPPGTSMRRWAHALADAAREPPRTAEVEL 3630 Query: 802 WRAVTSVPQAL---PPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLV 858 W+ + + P L V P +DT TA ++ + T LL VP AF V D LL Sbjct: 3631 WQGMLNAPDPLLGSRRVTP-SDTAATAADIAVRVPAPLTETLLTTVPRAFHGSVGDALLT 3689 Query: 859 AFGLAWTEFLNRSDTPIG---VDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLP 915 A +A T + R + V +EGHGR ++LA DL+RT+GWFTT +PV L + + Sbjct: 3690 ALTMALTSWRRRRGIELSGALVSLEGHGREEQLAPGADLARTIGWFTTIFPVRLDLSGVD 3749 Query: 916 WEQVVAGDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEVDLGGSD---PTIGFNYLG 971 + A + G VK VKEQL ++P+ G+ +G+LRYLN E S P + FNYLG Sbjct: 3750 LDDAFAAGPSAGAAVKTVKEQLLAVPDHGIGFGVLRYLNDETAQVLSPLPMPQVSFNYLG 3809 Query: 972 RLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWA 1031 R+G A +E +D+ +P+ V++NA T+D+ +GP L ++WT+ Sbjct: 3810 RMGPTATATAEGWVPVDEPGLREKS-----AVPVAAVVDVNAMTVDSGDGPQLNSTWTYP 3864 Query: 1032 PSAFDEEQATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRY-DVT 1090 P E+ L++LW +ALA + AH GGGG TPSD+ L Q I++L D+T Sbjct: 3865 PGVLTREEVEELAQLWVQALAALGAHAESGGGGFTPSDLDLVELRQDAIEDLEHVCPDLT 3924 Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 DV PL+P+Q G+LFHS A DVY VQ+ + + G +D RLR A ++ RH NL A Sbjct: 3925 DVWPLSPLQSGMLFHSELADD-SLDVYLVQVSLELEGTVDPRRLRRAADALLDRHANLRA 3983 Query: 1151 RFV-EQFGEPVQVLTADPMIAWRYLDLRG-DDLTPDHEIEQLCAAERSAVCDLLERPTFR 1208 F+ + G V V+ WR + L D+ E+ +L A +R DL P R Sbjct: 3984 GFLHDAEGNAVHVIRRRVEAPWRDVQLTALDEDAAAAEVARLLAEDRVRPFDLTRAPLIR 4043 Query: 1209 AALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP----YRNFVNWL 1264 LI T+ N++R V T HHI++DGWS+P+L++E+ Y P+ P YR+++ W+ Sbjct: 4044 FMLIATAPNRYRLVSTNHHILLDGWSMPLLVRELLTLYATDGDPSPLPRVRGYRDYLAWM 4103 Query: 1265 XXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIES-----YRVSAETTRALGELARS 1319 W L G + PTL+A PG R + + + T L ++ARS Sbjct: 4104 SRRDHGASREVWGRALAGVDGPTLLARSD-PGRRLSTMSDEFVFDLDEDHTTRLRDVARS 4162 Query: 1320 QHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVS 1379 + T+NT++Q AW +L +T + DV FG VSGRP +LAG E+MVGL INT+P+R ++ Sbjct: 4163 RGLTVNTLVQVAWGIVLGTLTARDDVLFGATVSGRPPELAGIETMVGLFINTLPVRVRLR 4222 Query: 1380 ADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQ 1439 D TVG LL ++Q+ L+H +L L +I +G E FDTL ++ESYP+D + Sbjct: 4223 PDDTVGALLERVQAEQAALLDHHYLGLAEIQSAAGPEVGFDTLTVFESYPVDRAGLSTET 4282 Query: 1440 ELA---VTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAM 1496 ++A VT + R+ HYPLS++A L L+ EY +FD I+ + R R+L+A Sbjct: 4283 DIAGMRVTGVDARDAAHYPLSLVASVDSRLRLKFEYLPDIFDADTIDDIAGRVLRVLDA- 4341 Query: 1497 IDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTF 1556 P R L+++ ++ D ER L V +P S +++P++ A DP A A++ Sbjct: 4342 CTRPDRPLAALSLLTDRERADL-----VPVRGRPGGSIRTLPQILAEGAALDPGAIALSS 4396 Query: 1557 EGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPID 1616 E ++YG+LDE +N+L+ L GA P VA+ +PRS D+I+++ AV KTGAA++PID Sbjct: 4397 EDGDVSYGDLDERSNRLSRALIARGAGPETFVAIGIPRSLDSILSVWAVAKTGAAFVPID 4456 Query: 1617 PSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEI-------YPSTTL 1669 P+ P R+ ML D+ VTT R R G +V +D+PA I P T Sbjct: 4457 PNYPDERITHMLVDSGVTLGVTTTAHRDRLPGAAHWLV-LDEPAFAIECAERAGAPVTDA 4515 Query: 1670 LTPSP---DDIAYMIYTSGTTGVPKGVAITHGNVTQ-VLDTLPAELPAGPGAVWSQWHSL 1725 P D AY +YTSG+TGVPKGV +TH + LD L A P + + + Sbjct: 4516 DRSGPVTLDTAAYAVYTSGSTGVPKGVVVTHRGLDNFALDQL-ERFGATPQSRTLHFSTP 4574 Query: 1726 VFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL 1785 FD SV+E A G +VI ++ G ++L LL V + T +A+ + P GL Sbjct: 4575 SFDGSVFEYLQAFGAGATMVIAAPTVFGG-EELARLLADRRVTHAFITTAALASLDPAGL 4633 Query: 1786 -EGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVP 1844 T LV GEACP E+V RWA R + NAYGPTE+TI + IS P+ PG+ + IG P+ Sbjct: 4634 VHLTDLVFGGEACPPELVARWAPGRRLYNAYGPTETTIMSNISEPMVPGNPIT-IGGPIR 4692 Query: 1845 KGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTG 1904 VLD L+PVP GV GELYLA LT RFVA P PG RMYRTG Sbjct: 4693 GVTELVLDPRLQPVPVGVPGELYLAGAGLARGYHRRPALTAERFVAHPV-RPGERMYRTG 4751 Query: 1905 DLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRL 1964 D+VRW D ++Y+GR D QVK+RG+RIELGEI + L V A +A GD L Sbjct: 4752 DIVRWTADRSIEYVGRTDFQVKVRGFRIELGEIDSTLMSEPDVGFAATLAHRGPAGDTLL 4811 Query: 1965 VGYITGTA----DPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS 2020 V Y+ + DP L +RLP++MVP ++ LE +PLT GKLDR ALP P+ S Sbjct: 4812 VSYVVPASGRSLDPVVLTRHLADRLPSHMVPTSITVLERIPLTAVGKLDRAALPEPDLLS 4871 Query: 2021 AQRY-RAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADL 2079 + R P E +A +FA VLG+ R A RV A + L D Sbjct: 4872 GTGHDRVPVGPIEDAVAVVFAEVLGLARVGADAGFFDIGGNSLSATRVMARLRALLGTDC 4931 Query: 2080 SVRTLFEAPTVAKLSLHVEH 2099 VR LFEAPTVA L+ +EH Sbjct: 4932 GVRDLFEAPTVAALAARIEH 4951 Score = 496 bits (1277), Expect = e-137 Identities = 370/1069 (34%), Positives = 531/1069 (49%), Gaps = 90/1069 (8%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ QQ + F + F Y + + + + G +D L+ A+ V+ RH +L F Sbjct: 2376 IPLSLAQQRMWFVNQF--DTSSPAYNIPVALDLDGAVDLTALQAALGDVMERHESLRTVF 2433 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALI 1212 P QV+ D +A LD + + A D+ E R L Sbjct: 2434 PGSADGPRQVIV-DSALATPELD---PVPVAEGALRDSLTAFFGVGFDVTEDLPIRVRLW 2489 Query: 1213 RTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVNWLX 1265 + +H L HHI DG+S+ L +++ Y + P AP Y ++ W Sbjct: 2490 ELAPERHVLALVAHHIAADGFSMAPLARDVMLAYTARAQQQAPGWAPLPVQYADYSLWQR 2549 Query: 1266 XXXXXXXXXX---------WREVLDGFETPTLVAPPGVPGPRGIES--------YRVSAE 1308 W L G V P + PR ++ + + Sbjct: 2550 AALGTEEQPDSMMSGQLGYWARTLSGIPD---VLPLPLDRPRPLQRSFLGDVVPFDIPPS 2606 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLL 1368 +AL ELAR ++T+ V+ AA LL R++G DV GT ++GR A + +VG+ Sbjct: 2607 VHKALTELARQYNSTLFMVVHAALAVLLERVSGSDDVVVGTPIAGRGH--AALDDVVGMF 2664 Query: 1369 INTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQLFDTL 1422 +NT+ +R V+ ++ D+L ++S EH L + + H LF L Sbjct: 2665 VNTLVLRTAVAPGSSFADVLTDVRSVDLGAFEHADLPFERLVDQLAPERSTAHSPLFQVL 2724 Query: 1423 FLYES-------YPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTS 1475 +++ P T+ + V +L V +F+ + + +P +G + Y T Sbjct: 2725 LEFQNATRTHLELPGLTARSLDV-DLDVAKFDLQLSLVERVDEQGVPAG-IGAGLRYATD 2782 Query: 1476 VFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQ 1535 VFD + +++ +RF R++EA+ DPA + +D++ ER + A+R P P Sbjct: 2783 VFDRASVKSFAERFVRVIEAVTTDPATPVGDIDILHAPERELVLTAAHRPGTDVP---PL 2839 Query: 1536 SIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRS 1595 S+ + F R V +A AV +G S+ Y LD+ AN+LA LL G V + + RS Sbjct: 2840 SLVDAFDRMVASAGDAVAVRCDGASMTYRALDDRANRLARLLVAQGVGAETLVVVGMTRS 2899 Query: 1596 ADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVE 1655 D +VA+LAV+KTGA YLP+D + PA RL F+LGDA+P +TT F G + VV Sbjct: 2900 IDLVVALLAVVKTGAGYLPVDVASPAERLAFVLGDARPECVLTTTADAGTFRGAGVPVVV 2959 Query: 1656 VDDP----AVEIYPSTTLL-----TP-SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLD 1705 +DDP A++ + S + TP D +AY+IYTSG+TG PKGV ++H NV +L Sbjct: 2960 LDDPETVTALQQFSSLPVTDDDRRTPLHLDSVAYVIYTSGSTGQPKGVQVSHRNVITLLA 3019 Query: 1706 TLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSE 1765 GP VW+ +HS FD SVWE+WGAL HGGRLV+V A SP+ LL E Sbjct: 3020 NTQTLFGFGPADVWTMFHSAAFDFSVWEMWGALAHGGRLVLVDYFTARSPERFLELLRGE 3079 Query: 1766 GVNVLYQTPSAV-------RMMSPEGLEGTALVVAGEACPTEVVDRWAVDR-----VMIN 1813 V V+ QTP+A R+ GL ++ GEA + RW R V++N Sbjct: 3080 TVTVVNQTPTAFYQLAEADRLAGGPGLSLRYVIFGGEALEFGQLRRWYARRGDAAPVLVN 3139 Query: 1814 AYGPTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAX 1870 YG TE+T++ + I L IG +P +VLD L PVPPGVVGE+Y++ Sbjct: 3140 MYGITETTVHVSHLPIHRDLVEEESASVIGRGLPGLRVYVLDGRLHPVPPGVVGEMYVSG 3199 Query: 1871 XXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGY 1930 LT RFVA PF PGARMYR+GDL RW GQL+YLGR D QV+++GY Sbjct: 3200 AQVSRGYLGRAALTSGRFVADPF-TPGARMYRSGDLGRWNGHGQLEYLGRNDLQVQVKGY 3258 Query: 1931 RIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYI---TGTA-DPAAARSELTNRLP 1986 RIELGE++AAL +GV Q+VV AR D RLVGY+ TG A DPAA RL Sbjct: 3259 RIELGEVEAALLACEGVAQSVVTARGD-----RLVGYVVPETGAAIDPAAIIDAAAVRLA 3313 Query: 1987 AYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGIFAHVLGV 2045 ++MVPAAVV L+ LP TVNGKLDR+ALP P++ Q R P TETE+ LA +FA VLG+ Sbjct: 3314 SHMVPAAVVVLDELPRTVNGKLDRKALPEPDFGQRVTAGRGPVTETERILADLFAEVLGL 3373 Query: 2046 ERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 + ++++ A +S R +FE TVA L+ Sbjct: 3374 DSVGVDDSFFTLGGDSIMSIQLVTRAKGA-GILISPREVFERKTVAGLA 3421 Score = 459 bits (1181), Expect = e-126 Identities = 315/837 (37%), Positives = 431/837 (51%), Gaps = 64/837 (7%) Query: 1304 RVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAES 1363 ++ AE A+ LA TT +VL AA+T LL R++G DV GT + Sbjct: 506 QIGAEAHAAVLALAHEHDTTAFSVLHAAFTVLLSRLSGASDVMIGTTTTADHGR------ 559 Query: 1364 MVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEH---------LALNDIHHVSG 1414 N V +R +V DT LL ++ + EH LAL D S Sbjct: 560 ------NLVALRTRVEPDTHFTHLLGHVRDIDREAFEHRDVPFERVVRTLALGDSPAYSP 613 Query: 1415 HEQLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDT 1474 Q+ L E ++ +G +L VT N + + P + A G + T Sbjct: 614 IVQV-----LLECRDEAETSGIGRLDLRVTATENSDADGIPSGITATLG--------FAT 660 Query: 1475 SVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSP 1534 +FD + L +RF+R+LE DDP + +D++ D ER L V P Sbjct: 661 DLFDPDTVRRLGERFRRILETTADDPGLVVGDLDILSDTERATLVP-----VSGSPGRPG 715 Query: 1535 QSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPR 1594 +++PE+F+ +P+ A+++ G + Y E+DE +NQLA +LA G P VAL R Sbjct: 716 RTLPELFSAAARTNPDGIALSYRGTEVTYREVDERSNQLARVLAGRGIGPENFVALGTTR 775 Query: 1595 SADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRF-DGFDLQV 1653 S ++++++LAV K+GAAY+P+DP+ PA R+E MLGD+ +T +RS D V Sbjct: 776 SIESVLSMLAVAKSGAAYVPVDPNYPAERIEHMLGDSGAALGITVSAVRSLLPDAIPWLV 835 Query: 1654 VEVDD--------PAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLD 1705 ++ D+ P + + ++ +Y+IYTSG+TG PKGV +THG LD Sbjct: 836 LDDDEFRTHCAAHPVSVVTDAERARPLRVENPSYVIYTSGSTGRPKGVVVTHGG----LD 891 Query: 1706 TLPAELPAGPGAVWSQ----WHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHAL 1761 AE + GA + + + FD SV E +VIVP ++ G + L Sbjct: 892 NFAAEQRSRFGATETSRILHFSTPSFDASVSEYLHVFAAAATMVIVPPTVYGGAE-LSRF 950 Query: 1762 LVSEGVNVLYQTPSAVRMMSPEGLEGTALVV-AGEACPTEVVDRWAVDRVMINAYGPTES 1820 L SE V + T +A+ + P+GL VV GEACP E+V+RWA R + NAYGP+E+ Sbjct: 951 LKSERVTHGFVTTAALGTVEPDGLADLGDVVFGGEACPPELVERWAPGRRLSNAYGPSEA 1010 Query: 1821 TIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXX 1880 T+ + ISAP+SP + + +G P+ VLD L+PVPPGV GELY+A Sbjct: 1011 TVMSNISAPMSP-TGTITVGGPLRGFHEVVLDARLQPVPPGVAGELYVAGDGLARGYHGK 1069 Query: 1881 XXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAA 1940 LT RFVA PFG PG RMYRTGD+VRW D L+YLGR D QVKIRG+RIE GEI Sbjct: 1070 SALTAERFVANPFGGPGERMYRTGDVVRWRTDLSLEYLGRIDFQVKIRGFRIEPGEIDTV 1129 Query: 1941 LSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSEL----TNRLPAYMVPAAVVT 1996 L V A+ + R GD LV Y+ A A EL +LP YMVPAA+V Sbjct: 1130 LHAHPRVRTAMTMPRTAPSGDTVLVSYVLPAAGHQLATRELIDYAAEQLPTYMVPAAIVV 1189 Query: 1997 LETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXX 2055 L+ +P+T GKLDR ALPAPE+ S A +RAP T E+ +A +FA VLGVER Sbjct: 1190 LDEIPMTPVGKLDRAALPAPEFLSTATEFRAPATPVERAVARVFADVLGVERIGLDDSFF 1249 Query: 2056 XXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAA 2112 A +V A VN AL DL VRTLFEAPTV L+ +E R DR A Sbjct: 1250 DLGGNSLVATKVVARVNAALGIDLVVRTLFEAPTVEALADRIEGTHARRPDRPDLVA 1306 Score = 457 bits (1175), Expect = e-125 Identities = 357/1118 (31%), Positives = 538/1118 (48%), Gaps = 111/1118 (9%) Query: 1048 FEA--LAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFH 1105 FEA +A + A + G G + V AR D +PL+ QQ + F Sbjct: 4937 FEAPTVAALAARIEHAGAGPSGHPVLAARSRP-------------DDIPLSYAQQRMWFV 4983 Query: 1106 STFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQ-VLT 1164 + Y + + ++++G LD L A+ VVARH +L F + PVQ +L Sbjct: 4984 NQL--DTTSAAYNIPIVVSLSGALDVGALNSALTDVVARHESLRTMFPVRGDWPVQQILP 5041 Query: 1165 ADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLT 1224 A+ + L + +H + + SA D+ R RA L S +H + Sbjct: 5042 AEGAVP----TLTPVPVADEHGLREELTRLVSAGFDVTVRIPLRAGLYSLSDTEHVLAVV 5097 Query: 1225 FHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP--------YRNFVNWLXXXXXXXXXXX- 1275 HHI DG+S+ L++++ Y G R+ AP Y ++ W Sbjct: 5098 VHHISADGFSMVPLVRDVMTAY-GARVGGGAPDWPPLPVQYADYALWQRESLGSDDDPRS 5156 Query: 1276 --------WREVLDG----FETPTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHT 1322 W L G E PT P RG + V ++ R +GEL+R + Sbjct: 5157 LISRQLDYWTTTLAGAPDLLELPTDRDRPSQQSFRGARIHFAVDSDLHRRIGELSRRLGS 5216 Query: 1323 TINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADT 1382 T + AA LL R+ G DVA G ++GR D A + +VG+ + T+ +R +V A Sbjct: 5217 TEFMTVHAALAVLLSRLGGTPDVAVGAPIAGR-GDPA-LDDLVGMFVGTLALRTQVDA-- 5272 Query: 1383 TVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELA 1442 + L +H D ++ E A D+ E++ D + P ++A+ + +++ Sbjct: 5273 --AESFTALAAHCRD-VDLEAFAHADVPF----ERVVDAVG-----PTRSTAYAPLVQVS 5320 Query: 1443 VTEFNNREYNHYPLSVMALPGHELGLRV--------------------------EYDTSV 1476 + EF N E L + + G + GL V ++ T + Sbjct: 5321 L-EFQNNERPVLTLPGLEVRGIDPGLAVVKVDLEFLLAEEFDANGAPAGMNGAVDFATDL 5379 Query: 1477 FDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQS 1536 FD + DRF R+L+A+ +P R + + ++D+ E A +P P+ Sbjct: 5380 FDSDTVRGFADRFVRILDAVTANPDRPIGDLPLLDEVELR-----AMVPARGEPQVRPEL 5434 Query: 1537 IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSA 1596 P++ DP++ A++FE ++Y +LDE +N++A +L G P VA+ +PRS Sbjct: 5435 WPDLLTAAAALDPDSVALSFEDRRVSYRQLDEWSNRVARVLRGRGVGPETFVAVGMPRSI 5494 Query: 1597 DAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRF-DGFDLQVVE 1655 +++V+I ++ K GAA++P+DP+ P R+++ML D + +T RS D +++ Sbjct: 5495 ESVVSIWSITKAGAAFVPVDPTYPRDRIDYMLIDCRAALGLTVRSRRSTLPDTVPWLILD 5554 Query: 1656 VDD-----PAVEIYPSTTLLTPSPDDI---AYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 +D AV P T +P + AY+IYTSG+TG PKGV +TH + Sbjct: 5555 DEDFATQASAVSSAPITDADRTNPLHLAHPAYLIYTSGSTGRPKGVTVTHRGMADFTAET 5614 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 + SQ S FD SV+E+ A R+VIVP +I G +L L E V Sbjct: 5615 HQRFQVTHESRVSQLASPSFDASVFELMMAFSASARVVIVPPAIVGG-SELADLFRREQV 5673 Query: 1768 NVLYQTPSAVRMMSPEGLEG-TALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAI 1826 TP+A+ + +GL+ L + GEACP EVV RWA R + + YGPTE+TI A++ Sbjct: 5674 THATITPTALAALDNDGLDSLRVLDLVGEACPPEVVARWAPGRSLHSGYGPTETTIQASV 5733 Query: 1827 SAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGT 1886 S P+ PG + V IG+P A VLDE L+PVP GV GELY+A LT Sbjct: 5734 SDPMRPG-ESVNIGAPARGFAFLVLDERLQPVPVGVPGELYIAGPGMARGYHNRAALTSE 5792 Query: 1887 RFVACPFGEPGARMYRTGDLVRWGDDGQ-LQYLGRADEQVKIRGYRIELGEIQAALSDVD 1945 RFVAC FGEPG RMYRTGD+VRW + L+Y+GR+D QVK+RG+RIELGEI A L+ Sbjct: 5793 RFVACNFGEPGCRMYRTGDVVRWRESASALEYIGRSDFQVKVRGFRIELGEIDAVLTRHP 5852 Query: 1946 GVDQAVVIAREDRPGDKRLVGYITG----TADPAAARSELTNRLPAYMVPAAVVTLETLP 2001 V A I GD L Y+ PA R+ + RLPA+MVP+AVV L+ +P Sbjct: 5853 AVAFAATIGHIGPSGDTVLASYVRAQDGQEVQPAGLRTYASERLPAHMVPSAVVVLDRIP 5912 Query: 2002 LTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXX 2060 +T GKLDR+ALPAPE+ S +RAP TE E+ + F VLGV+R Sbjct: 5913 MTPVGKLDRKALPAPEFGSTGAAFRAPATENERIVVDAFTEVLGVDRVGTADSFFDLGGN 5972 Query: 2061 XXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVE 2098 A R+ A+ ALD + ++ +F PT A ++ ++ Sbjct: 5973 SLLATRIVGALQAALDRRVPLQWMFLDPTPAGIARRLD 6010 Score = 425 bits (1093), Expect = e-116 Identities = 334/1075 (31%), Positives = 492/1075 (45%), Gaps = 93/1075 (8%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D +PL+ QQ + F + + Y + + + ++G LD LR V V+ RH +L Sbjct: 1311 DRIPLSLAQQRMWFVNQY--DTSSPAYNIPMALRLSGTLDVEALRATVADVLERHESLRT 1368 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTP----DHEIEQLCAAERSAV-CDLLERP 1205 + P QV+ + DL P D + + AE +A D+ Sbjct: 1369 VYPASVDGPQQVILPPGEVI--------PDLEPTVCEDEDAVRARIAELTARGFDVSTEV 1420 Query: 1206 TFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP--------Y 1257 R AL RT +++ +L HHI DG SL L ++ Y R+ AP Y Sbjct: 1421 PVRGALFRTGHDENVLILVVHHISADGASLAPLAHDLMVAY-SVRIQQQAPDWRPLPVQY 1479 Query: 1258 RNFVNWLXXXXXXXXXXX---------WREVLDGFETPTLVAPPGVPGPR------GIES 1302 ++ W W++ L G + P P P GI Sbjct: 1480 ADYSLWQRAALGSDENPDSMMSAQLEYWKQTLSGLPD-AIDLPLDRPRPADRALRGGIVR 1538 Query: 1303 YRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAE 1362 + VSAE RAL +AR ++T+ V+ A L R++G D+A GT ++GR + + Sbjct: 1539 FPVSAEQHRALLLIARQHNSTMFMVMHAVLAVLAARLSGSGDIAIGTPIAGRGEE--ALD 1596 Query: 1363 SMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHV------SGHE 1416 +VG+L+NT+ +R V T ++L + + H + + + + Sbjct: 1597 DVVGMLVNTLVLRTTVEPAATFAEVLSRAREADLAAFGHAEVPFESVVDTVAPTRSTAYS 1656 Query: 1417 QLFDTLFLYESYP-------------IDTSAFMGVQELAVTEFNNREYNHYPLSVMALPG 1463 LF L +++ +D + + +L +T + + P V A Sbjct: 1657 PLFQVLLEFQNTAPAHLDLPGLTVEILDVDSGVSKFDLQLTLAERYDASGTPAGVDA--- 1713 Query: 1464 HELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWAN 1523 + + VFD + +RF R+L ++ DP + ++V+ ER + N Sbjct: 1714 -----SFTFASDVFDPDTVTGFGERFLRILAGLVADPDTAVGDVEVLGPGERALVVGSWN 1768 Query: 1524 RAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAA 1583 P ++ ++ QV R P A AV L+YGE D N+LA L G Sbjct: 1769 ATGHPVP---HTTLVDLLDAQVGRTPGAAAVVCGDVVLSYGEFDARVNRLARFLVAAGVG 1825 Query: 1584 PGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLR 1643 P SV + V RS + +V I AV+K G AY+PIDP PA R+ +++G A PV +T+ R Sbjct: 1826 PESSVGVAVRRSVEMLVGIYAVVKAGGAYVPIDPGQPAERVGYVVGIADPVLVLTSSADR 1885 Query: 1644 SRFDGFDLQVVEVDDPAVEIYPSTTLLTPS------PDDIAYMIYTSGTTGVPKGVAITH 1697 ++VVE+D V + + + P++ AY+I+TSG+TG PKGVA+ H Sbjct: 1886 VVVPA-GVRVVELDTLDVSGFSAGPVGDGDRSGPVRPENPAYVIFTSGSTGRPKGVAVPH 1944 Query: 1698 GNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDD 1757 V L + V Q + FDVSVWE++ L+ G RLVI P Sbjct: 1945 EGVVNRLLWMQDRYGLASDDVVLQKTPVTFDVSVWELFWPLIVGARLVIAEPDGHRDPAY 2004 Query: 1758 LHALLVSEGVNVLYQTPSAVRM-MSPEGLEGTA----LVVAGEACPTEVVD--RWAVDRV 1810 L ++ E V ++ PS + + ++ +EG + +GEA P+ R Sbjct: 2005 LERVIREESVTTVHFVPSMLEVFLAGANVEGCGALHRVFTSGEALPSATAARLRGVSGAE 2064 Query: 1811 MINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAX 1870 + N YGPTE+ + VVPIG+PV T+VLD LR VP GV GELYL Sbjct: 2065 LHNLYGPTEAAVDVTFHEVSGSDRTVVPIGAPVWNTQTYVLDGRLRVVPVGVAGELYLGG 2124 Query: 1871 XXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGY 1930 LT RFVA PFG R+YRTGD VRW G+L+YLGR D QVK+RG Sbjct: 2125 VQLARGYQGRADLTADRFVANPFGT--GRLYRTGDRVRWLPSGELEYLGRTDFQVKLRGQ 2182 Query: 1931 RIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAAARSELTNRLP 1986 R+ELGEI+A L + V QAVV+ R D + L GY+ A D R LP Sbjct: 2183 RVELGEIEAVLLRREDVAQAVVVLRGDGSSGEYLAGYVVPVAGAVVDERVVRESAAVALP 2242 Query: 1987 AYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQ-RYRAPETETEKTLAGIFAHVLGV 2045 +MVP+ VV L LP+TVNGKLDR+ALP P++ + YRAP T E+ +A FA VLGV Sbjct: 2243 GFMVPSVVVVLAELPVTVNGKLDRKALPEPDFGTRTIGYRAPTTPAEEAIATAFAAVLGV 2302 Query: 2046 ERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHD 2100 +R A R +N+ALD L V LF+AP V+ L++ ++ D Sbjct: 2303 DRVGADDSFFDLGGDSLSATRAVGRINSALDTALGVAALFDAPVVSDLAVRIDSD 2357 Score = 424 bits (1091), Expect = e-116 Identities = 323/929 (34%), Positives = 463/929 (49%), Gaps = 67/929 (7%) Query: 36 PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA 95 PG T+P LF+ PD +AL TYRE+DE SN+LA VLA G P VA Sbjct: 711 PGRPGRTLPELFSAAARTNPDGIALSYRGTEVTYREVDERSNQLARVLAGRGIGPENFVA 770 Query: 96 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRL-DQ 154 RS E++LS+L+V K+GAAY+PVDP +P RI M+ D+ +T + +RS L D Sbjct: 771 LGTTRSIESVLSMLAVAKSGAAYVPVDPNYPAERIEHMLGDSGAALGITVSAVRSLLPDA 830 Query: 155 YDLAVID--------MADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNV 206 V+D A P ++ R ++ +Y+ YTSG+TG PK V VTH + Sbjct: 831 IPWLVLDDDEFRTHCAAHPVSVVTDAERARPLRVENPSYVIYTSGSTGRPKGVVVTHGGL 890 Query: 207 TQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHN 266 + + + + + FD SV E +V+VP +V + L Sbjct: 891 DNFAAEQRSRFGATETSRILHFSTPSFDASVSEYLHVFAAAATMVIVPPTVYGGAE-LSR 949 Query: 267 LLITEKVSVLCQTPSAAGMLSPEGLEST-TLIVAGEACPTELVDRWAPGRVMINAYGPTE 325 L +E+V+ T +A G + P+GL ++ GEACP ELV+RWAPGR + NAYGP+E Sbjct: 950 FLKSERVTHGFVTTAALGTVEPDGLADLGDVVFGGEACPPELVERWAPGRRLSNAYGPSE 1009 Query: 326 ATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIG 385 AT+ + +S P+ + VLD L+P P GV GELYVAG G+A GY G Sbjct: 1010 ATVMSNISAPMSPTGTITVGGPLRGFHEV-VLDARLQPVPPGVAGELYVAGDGLARGYHG 1068 Query: 386 RPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQA 445 + LTA RFVA PFG GERMYRTGD+VRW +D LEYLGR D QVKIRG+RIE GEI Sbjct: 1069 KSALTAERFVANPFGGPGERMYRTGDVVRWRTDLSLEYLGRIDFQVKIRGFRIEPGEIDT 1128 Query: 446 ALAKLDGVDQAVVIAREDRPGDKRLVGYITGTAD----PAQLRTALAESLPAYMVPTAVV 501 L V A+ + R GD LV Y+ A +L AE LP YMVP A+V Sbjct: 1129 VLHAHPRVRTAMTMPRTAPSGDTVLVSYVLPAAGHQLATRELIDYAAEQLPTYMVPAAIV 1188 Query: 502 VLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSF 561 VLD IP+T GKLDR ALPAPE+ S A ++RAP+TP E+ +A V+A VLGVER+G+DDSF Sbjct: 1189 VLDEIPMTPVGKLDRAALPAPEFLSTATEFRAPATPVERAVARVFADVLGVERIGLDDSF 1248 Query: 562 FDLGGDSILSMQVVARARAA-GIQCRPRDIF-----------VEQTXXXXXXXXXXXXES 609 FDLGG+S+++ +VVAR AA GI R +F +E T ++ Sbjct: 1249 FDLGGNSLVATKVVARVNAALGIDLVVRTLFEAPTVEALADRIEGTHARRPDRPDLVAQT 1308 Query: 610 HVVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATL 669 + + +A M ++ + D + +N + + + + + + +L+RH +L Sbjct: 1309 R--PDRIPLSLAQQRMWFVNQYDTSSPAYNIPMALRLSGTLDVEALRATVADVLERHESL 1366 Query: 670 RLRVEDTQEDTDEWSLLVP-------------EAGAVGARECLRTVDALTDDVLVEARNR 716 R V D + +L P + AV AR + + A DV E Sbjct: 1367 R-TVYPASVDGPQQVILPPGEVIPDLEPTVCEDEDAVRAR--IAELTARGFDVSTEV--- 1420 Query: 717 LDPAAGAMVSAVWVRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LP 773 P GA+ + + L+L++HH++ DG S L DL +A++ Q+ + LP Sbjct: 1421 --PVRGALFRT--GHDENVLILVVHHISADGASLAPLAHDLMVAYSVRIQQQAPDWRPLP 1476 Query: 774 AGGTSFARW--SALLAEHAKTDTVRDLADAWR-AVTSVPQA--LPPVQP-DTDTYVTAGQ 827 ++ W +AL ++ + + W+ ++ +P A LP +P D + G Sbjct: 1477 VQYADYSLWQRAALGSDENPDSMMSAQLEYWKQTLSGLPDAIDLPLDRPRPADRALRGGI 1536 Query: 828 LSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDE 887 + + E R LL + + + ++ + D IG + G G +E Sbjct: 1537 VRFPVSAEQHRALL-LIARQHNSTMFMVMHAVLAVLAARLSGSGDIAIGTPIAGRG--EE 1593 Query: 888 LASDV--DLSRTVGWFTTKYPVALTVENL 914 DV L T+ TT P A E L Sbjct: 1594 ALDDVVGMLVNTLVLRTTVEPAATFAEVL 1622 Score = 413 bits (1061), Expect = e-112 Identities = 261/597 (43%), Positives = 341/597 (57%), Gaps = 25/597 (4%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA P R + LLDE +E+ +P P P L PD+VAL Sbjct: 5399 VTANPD-RPIGDLPLLDE-----VELRAMVPARGEPQVRPELWPDLLTAAAALDPDSVAL 5452 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 DR +YR+LDE SNR+A VL G P VA +PRS E+++SI S+ K GAA++P Sbjct: 5453 SFEDRRVSYRQLDEWSNRVARVLRGRGVGPETFVAVGMPRSIESVVSIWSITKAGAAFVP 5512 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRL-DQYDLAVIDMAD-----PAIDRRPSDA 174 VDP +P RI +M+ D + LT RS L D ++D D A+ P Sbjct: 5513 VDPTYPRDRIDYMLIDCRAALGLTVRSRRSTLPDTVPWLILDDEDFATQASAVSSAPITD 5572 Query: 175 LSGPRPDDLA---YMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSL 231 P LA Y+ YTSG+TG PK V VTH + + H SQ S Sbjct: 5573 ADRTNPLHLAHPAYLIYTSGSTGRPKGVTVTHRGMADFTAETHQRFQVTHESRVSQLASP 5632 Query: 232 VFDVSVWEIWGALLHGGRLVVVPES-VGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEG 290 FD SV+E+ A R+V+VP + VG S +L +L E+V+ TP+A L +G Sbjct: 5633 SFDASVFELMMAFSASARVVIVPPAIVGGS--ELADLFRREQVTHATITPTALAALDNDG 5690 Query: 291 LESTTLI-VAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXX 349 L+S ++ + GEACP E+V RWAPGR + + YGPTE TI A++S+P+ Sbjct: 5691 LDSLRVLDLVGEACPPEVVARWAPGRSLHSGYGPTETTIQASVSDPMRPGESVNIGAPAR 5750 Query: 350 XXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRT 409 L VLD+ L+P P GV GELY+AG G+A GY R LT+ RFVAC FGE G RMYRT Sbjct: 5751 GFAFL-VLDERLQPVPVGVPGELYIAGPGMARGYHNRAALTSERFVACNFGEPGCRMYRT 5809 Query: 410 GDLVRWG-SDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDK 468 GD+VRW S LEY+GR+D QVK+RG+RIELGEI A L + V A I GD Sbjct: 5810 GDVVRWRESASALEYIGRSDFQVKVRGFRIELGEIDAVLTRHPAVAFAATIGHIGPSGDT 5869 Query: 469 RLVGYITGT----ADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEY 524 L Y+ PA LRT +E LPA+MVP+AVVVLD IP+T GKLDR+ALPAPE+ Sbjct: 5870 VLASYVRAQDGQEVQPAGLRTYASERLPAHMVPSAVVVLDRIPMTPVGKLDRKALPAPEF 5929 Query: 525 RSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA 581 S +RAP+T E+I+ D + +VLGV+RVG DSFFDLGG+S+L+ ++V +AA Sbjct: 5930 GSTGAAFRAPATENERIVVDAFTEVLGVDRVGTADSFFDLGGNSLLATRIVGALQAA 5986 Score = 407 bits (1047), Expect = e-111 Identities = 321/934 (34%), Positives = 449/934 (48%), Gaps = 89/934 (9%) Query: 8 RTLLSFDLL-DEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRS 66 R L + LL D + D + V G PG + T+P + AE P A+AL S D Sbjct: 4347 RPLAALSLLTDRERADLVPVRGR------PGGSIRTLPQILAEGAALDPGAIALSSEDGD 4400 Query: 67 WTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHP 126 +Y +LDE SNRL+ L GA P VA IPRS ++ILS+ +V KTGAA++P+DP +P Sbjct: 4401 VSYGDLDERSNRLSRALIARGAGPETFVAIGIPRSLDSILSVWAVAKTGAAFVPIDPNYP 4460 Query: 127 DARIGFMMSDAKPVAALTTADLRSRL---------DQYDLAVIDMADPAIDRRPSDALSG 177 D RI M+ D+ +TT R RL D+ A I+ A+ A SG Sbjct: 4461 DERITHMLVDSGVTLGVTTTAHRDRLPGAAHWLVLDEPAFA-IECAERAGAPVTDADRSG 4519 Query: 178 PRP-DDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVS 236 P D AY YTSG+TGVPK V VTH + + P + + FD S Sbjct: 4520 PVTLDTAAYAVYTSGSTGVPKGVVVTHRGLDNFALDQLERFGATPQSRTLHFSTPSFDGS 4579 Query: 237 VWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGL-ESTT 295 V+E A G +V+ +V ++L LL +V+ T +A L P GL T Sbjct: 4580 VFEYLQAFGAGATMVIAAPTVFGG-EELARLLADRRVTHAFITTAALASLDPAGLVHLTD 4638 Query: 296 LIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLF 355 L+ GEACP ELV RWAPGR + NAYGPTE TI + +SEP+ L Sbjct: 4639 LVFGGEACPPELVARWAPGRRLYNAYGPTETTIMSNISEPMVPGNPITIGGPIRGVTEL- 4697 Query: 356 VLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRW 415 VLD L+P P GV GELY+AG G+A GY RP LTA RFVA P GERMYRTGD+VRW Sbjct: 4698 VLDPRLQPVPVGVPGELYLAGAGLARGYHRRPALTAERFVAHPV-RPGERMYRTGDIVRW 4756 Query: 416 GSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT 475 +D +EY+GR D QVK+RG+RIELGEI + L V A +A GD LV Y+ Sbjct: 4757 TADRSIEYVGRTDFQVKVRGFRIELGEIDSTLMSEPDVGFAATLAHRGPAGDTLLVSYVV 4816 Query: 476 GTA----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDY 531 + DP L LA+ LP++MVPT++ VL+ IPLT GKLDR ALP P+ S Sbjct: 4817 PASGRSLDPVVLTRHLADRLPSHMVPTSITVLERIPLTAVGKLDRAALPEPDLLSGTGHD 4876 Query: 532 RAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDI 590 R P P E +A V+A+VLG+ RVG D FFD+GG+S+ + +V+AR RA G C RD+ Sbjct: 4877 RVPVGPIEDAVAVVFAEVLGLARVGADAGFFDIGGNSLSATRVMARLRALLGTDCGVRDL 4936 Query: 591 FVEQTXXXXXXXXXXXXESHVVDEGVGPV-----------------VATPIMRWLREVDG 633 F T + + G GP A M ++ ++D Sbjct: 4937 FEAPTVAALA--------ARIEHAGAGPSGHPVLAARSRPDDIPLSYAQQRMWFVNQLDT 4988 Query: 634 PTGQFNQTVITQAPAGVTEDDVVVILQALLD---RHATLRLRVEDTQEDTDEWSL--LVP 688 + +N ++ + DV + AL D RH +LR +W + ++P Sbjct: 4989 TSAAYNIPIVVSLSGAL---DVGALNSALTDVVARHESLRTMFPVR----GDWPVQQILP 5041 Query: 689 EAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVR-------ETSQ-LVLMI 740 GAV L V + L E RL A + + +R +T L +++ Sbjct: 5042 AEGAVPT---LTPVPVADEHGLREELTRLVSAGFDVTVRIPLRAGLYSLSDTEHVLAVVV 5098 Query: 741 HHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFARW--SALLAEHAKTDTV 795 HH++ DG S L+ D+ A+ G + + LP +A W +L ++ + Sbjct: 5099 HHISADGFSMVPLVRDVMTAYGARVGGGAPDWPPLPVQYADYALWQRESLGSDDDPRSLI 5158 Query: 796 RDLADAWRAVTSVPQALPPVQPDTD----TYVTAGQLSASLDVETTRQLLGEVPAAFRAG 851 D W + L + D D ++ ++D + R+ +GE+ + R G Sbjct: 5159 SRQLDYWTTTLAGAPDLLELPTDRDRPSQQSFRGARIHFAVDSDLHRR-IGEL--SRRLG 5215 Query: 852 VQDILLV--AFGLAWTEFLNRSDTPIGVDVEGHG 883 + + V A + + D +G + G G Sbjct: 5216 STEFMTVHAALAVLLSRLGGTPDVAVGAPIAGRG 5249 Score = 379 bits (973), Expect = e-102 Identities = 279/816 (34%), Positives = 397/816 (48%), Gaps = 47/816 (5%) Query: 38 PTP-VTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAF 96 P P T+ L QV R P A A+V GD +Y E D NRLA L G P ++V Sbjct: 1773 PVPHTTLVDLLDAQVGRTPGAAAVVCGDVVLSYGEFDARVNRLARFLVAAGVGPESSVGV 1832 Query: 97 LIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLR----SRL 152 + RS E ++ I +V+K G AY+P+DP P R+G+++ A PV LT++ R + + Sbjct: 1833 AVRRSVEMLVGIYAVVKAGGAYVPIDPGQPAERVGYVVGIADPVLVLTSSADRVVVPAGV 1892 Query: 153 DQYDLAVIDMADPAIDRRPSDALSGP-RPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVS 211 +L +D++ + SGP RP++ AY+ +TSG+TG PK VAV H V + Sbjct: 1893 RVVELDTLDVSGFSAGPVGDGDRSGPVRPENPAYVIFTSGSTGRPKGVAVPHEGVVNRLL 1952 Query: 212 ALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITE 271 + V Q + FDVSVWE++ L+ G RLV+ P L ++ E Sbjct: 1953 WMQDRYGLASDDVVLQKTPVTFDVSVWELFWPLIVGARLVIAEPDGHRDPAYLERVIREE 2012 Query: 272 KVSVLCQTPSAAGML----SPEGLEST-TLIVAGEACPTELVDRW--APGRVMINAYGPT 324 V+ + PS + + EG + + +GEA P+ R G + N YGPT Sbjct: 2013 SVTTVHFVPSMLEVFLAGANVEGCGALHRVFTSGEALPSATAARLRGVSGAELHNLYGPT 2072 Query: 325 EATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYI 384 EA + E +VLD LR P GV GELY+ G +A GY Sbjct: 2073 EAAVDVTFHEVSGSDRTVVPIGAPVWNTQTYVLDGRLRVVPVGVAGELYLGGVQLARGYQ 2132 Query: 385 GRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQ 444 GR DLTA RFVA PFG TG R+YRTGD VRW G+LEYLGR D QVK+RG R+ELGEI+ Sbjct: 2133 GRADLTADRFVANPFG-TG-RLYRTGDRVRWLPSGELEYLGRTDFQVKLRGQRVELGEIE 2190 Query: 445 AALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAQLRTALAESLPAYMVPTAV 500 A L + + V QAVV+ R D + L GY+ A D +R + A +LP +MVP+ V Sbjct: 2191 AVLLRREDVAQAVVVLRGDGSSGEYLAGYVVPVAGAVVDERVVRESAAVALPGFMVPSVV 2250 Query: 501 VVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDS 560 VVL +P+TVNGKLDR+ALP P++ + YRAP+TPAE+ +A +A VLGV+RVG DDS Sbjct: 2251 VVLAELPVTVNGKLDRKALPEPDFGTRTIGYRAPTTPAEEAIATAFAAVLGVDRVGADDS 2310 Query: 561 FFDLGGDSILSMQVVARARAA-----GIQCR-----PRDIFVEQTXXXXXXXXXXXXESH 610 FFDLGGDS+ + + V R +A G+ D+ V + Sbjct: 2311 FFDLGGDSLSATRAVGRINSALDTALGVAALFDAPVVSDLAVRIDSDVRTSSASPALTAT 2370 Query: 611 VVDEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLR 670 E + +A M ++ + D + +N V V + L +++RH +LR Sbjct: 2371 ARPERIPLSLAQQRMWFVNQFDTSSPAYNIPVALDLDGAVDLTALQAALGDVMERHESLR 2430 Query: 671 L----RVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVS 726 + ++ + +L PE V E AL D + D + Sbjct: 2431 TVFPGSADGPRQVIVDSALATPELDPVPVAE-----GALRDSLTAFFGVGFDVTEDLPIR 2485 Query: 727 A-VW--VRETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQS---IELPAGGTSFA 780 +W E L L+ HH+A DG S L D+ +A+ Q+ LP ++ Sbjct: 2486 VRLWELAPERHVLALVAHHIAADGFSMAPLARDVMLAYTARAQQQAPGWAPLPVQYADYS 2545 Query: 781 RW--SALLAEHAKTDTVRDLADAW-RAVTSVPQALP 813 W +AL E + W R ++ +P LP Sbjct: 2546 LWQRAALGTEEQPDSMMSGQLGYWARTLSGIPDVLP 2581 Score = 62.0 bits (149), Expect = 1e-06 Identities = 90/450 (20%), Positives = 176/450 (39%), Gaps = 43/450 (9%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 + + G LD LR V + + VE G P+Q + + ++D RG+D Sbjct: 57 VELHGDLDIDLLRRETIAVAREFQSPFLKVVEVDGRPMQYVDHATDTSIAFIDFRGED-D 115 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 P + + A DL F +++ + + + HH+ +DG+ ++ I Sbjct: 116 PVAAAHEWMDRDYQAPLDLDADRLFETSILCVGESHYLWYSRIHHVALDGYGAMTVINRI 175 Query: 1243 ---FAGYFGHRLP----AAAPYRNF---VNWLXXXXXXXXXXXWREVLDGFETPTLVAPP 1292 ++ R P AA + + + W + ++ + TL P Sbjct: 176 AHRYSAVVAGREPDPSRAATLHELYDVDARYRSSDRFVADREYWAKRVEAVDGSTLADTP 235 Query: 1293 GVPGPRG-IESYRVSAETTRAL-GELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTA 1350 R +ES +S + G +R+ T T++ AA+ L R T + DV Sbjct: 236 APALARSKVESALLSEAAVSGIHGADSRANATAAVTII-AAFACYLSRTTAKTDVLVNVP 294 Query: 1351 VSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIH 1410 +SGR + + G++++ P+ V D TV DL+ +++ L H+ ++ DI Sbjct: 295 MSGRTTSVL--RNSGGMMVSVAPLPITVDEDETVADLVSRVRRELMGALRHQRCSVEDIR 352 Query: 1411 HVSG-------HEQLFDTLFLYESYPIDTSAFMGVQELAVT-EFNNREYNHYPLSVMALP 1462 G H + + + +++ + +G + + + N YP A Sbjct: 353 RDVGAGSGADLHGPMVNVMLFHQN--VQLGPLVGEYHIVTSGPVEDLLVNVYPSGTPA-- 408 Query: 1463 GHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMID-DPARRLSSMDVVD--DDERTQLD 1519 E+ + + + ++ + + F LLE I DP R++++ V D ER +L+ Sbjct: 409 --EIYVDFRANPNRYEDAALRLHHRHFVELLEEFISADPQARVATIHEVTARDGERRRLE 466 Query: 1520 E-----WANR-----AVLTQPVDSPQSIPE 1539 W ++ VL P D P+ + + Sbjct: 467 AHQLAYWTDQLSGMPEVLNLPSDRPRPVEQ 496 >tr|D5PLG3|D5PLG3_COREQ Tax_Id=525370 (ppx8)SubName: Full=Exopolyphosphatase; EC=3.6.1.11;[Rhodococcus equi ATCC 33707] Length = 8934 Score = 1338 bits (3463), Expect = 0.0 Identities = 859/2163 (39%), Positives = 1176/2163 (54%), Gaps = 120/2163 (5%) Query: 42 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRS 101 T+ FA R PD AL + Y ELD +NRLA L G P VA +PRS Sbjct: 5463 TLADRFALAAARFPDRPALTYEASTLGYAELDARANRLARHLVSLGVGPETLVAVALPRS 5522 Query: 102 GEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTT-ADLRS---------R 151 + ++++L+V+K+GA YLP+D +P R+ +M++DA PV LTT AD + R Sbjct: 5523 ADLVVALLAVIKSGAGYLPLDVTYPAERLSYMLTDAAPVCVLTTGADANAIPSTDVPLIR 5582 Query: 152 LDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVS 211 LD + A A P +D L+ RPDD+AY+ YTSG+TG PK V VTH NV L + Sbjct: 5583 LDTDETAAALAAAPDRAVTDADRLTPLRPDDVAYVIYTSGSTGRPKGVQVTHRNVLTLFA 5642 Query: 212 ALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITE 271 VW+ +HS FD SVWE+WG LLHGGRLVVV SP+ +LL TE Sbjct: 5643 NTTGAFGFDEHDVWTMFHSYAFDFSVWELWGPLLHGGRLVVVDFYTARSPEMFLDLLRTE 5702 Query: 272 KVSVLCQTPSAAGML-------SPEGLESTTL-----IVAGEACPTELVDRW-------A 312 +V+VL QTP+A L S +G +T L + GEA + RW A Sbjct: 5703 QVTVLNQTPTAFYQLAEADRLASEQGTTATDLALRYVVFGGEALDLGQLGRWYTRHPDSA 5762 Query: 313 PGRVMINAYGPTEATIYAA---MSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVV 369 P ++N YG TE T++ + + VLD+ L P GVV Sbjct: 5763 PR--LVNMYGITETTVHVTHLELDRAFAEAADASVIGRAIPGLRVVVLDERLHSVPPGVV 5820 Query: 370 GELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADE 429 GE+YVAG + GY+GR LT+SRFVA PFG G RMYRTGDL RW DG+LEYLGR+D Sbjct: 5821 GEMYVAGEQLTRGYLGRSALTSSRFVADPFGAPGSRMYRTGDLARWNRDGRLEYLGRSDF 5880 Query: 430 QVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITG----TADPAQLRT 485 QVKIRG+RIELGEI+AAL + GV QAVV D G RLVGY DP + Sbjct: 5881 QVKIRGFRIELGEIEAALLRYPGVAQAVVAVHRDGTGPARLVGYAVPEQGLDVDPQDVLG 5940 Query: 486 ALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADV 545 + L +YMVP +++LD +PLT NGKLDR+ALP PE+ + A RAP T E+ LA + Sbjct: 5941 HVGRELTSYMVPATLMLLDELPLTANGKLDRKALPQPEFGTGAARGRAPETDVERTLAGL 6000 Query: 546 YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQT-XXXXXXXXX 604 +A+VLG++ VGVDDSFF LGGDSI+S+Q+V+RA+ AG++ PRD+F ++ Sbjct: 6001 FAEVLGLDSVGVDDSFFGLGGDSIMSIQLVSRAKDAGLRFTPRDVFEHRSVAGLAAVAAA 6060 Query: 605 XXXESHV-VDE----GVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVIL 659 E+ V +DE GVG TPIM WL E ++ QT + P+G D + L Sbjct: 6061 DSGETPVHLDELPGGGVGEFPLTPIMHWLLERSDDVRRYTQTALLALPSGTDRDRLARTL 6120 Query: 660 QALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR--TVDALTDD--------V 709 QA++DRH LR ++ + +LV GAV A + + VDAL+ Sbjct: 6121 QAVVDRHDMLRAQLHTGPDP----HMLVRPVGAVDADDLITRIPVDALSGPDFTAVAGAA 6176 Query: 710 LVEARNRLDPAAGAMVSAVW--VRET-SQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCT 766 L +A RLDPAAGA++ AVW ET +L+L+IHHLAVDGVSWRIL+ DL AW + Sbjct: 6177 LDDAAGRLDPAAGAVLQAVWFDAGETGGRLLLVIHHLAVDGVSWRILVPDLAAAWTRIAA 6236 Query: 767 GQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQAL---PPVQPDTDTYV 823 G+ +L GTS RW+ LA+ A R+L + W+ P + P+ P D Y Sbjct: 6237 GELPDLAPTGTSMRRWAHGLAD-ATAGRDREL-ELWQGTLDTPDPVIGSRPLDPAVDVYG 6294 Query: 824 TAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEF--LNRSDTPIG-VDVE 880 T ++S L T LL VP FR V D LL A +A T + +DT V++E Sbjct: 6295 TVDKVSVELPSAVTEALLTTVPEVFRGNVNDALLTALAMALTRWRRTRGADTDAALVNLE 6354 Query: 881 GHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSL 940 GHGR D++ DL RTVGWFTT +PV L + + + A A G +KAVKEQL ++ Sbjct: 6355 GHGREDQVVPGADLGRTVGWFTTIFPVRLDLTGIDVDDAFAAGPAAGAALKAVKEQLLAI 6414 Query: 941 PE-GLTYGLLRYLNPEVDLGGSD---PTIGFNYLGRLGAGAGELSEELWRIDQXXXXXXX 996 P+ G+ +G+LRYL+P ++ P +GFNYLGRLG G ++ W Sbjct: 6415 PDHGIGFGMLRYLDPRTGPVLAELPVPQVGFNYLGRLG-GTSTGTDVPW--VPVSDTELD 6471 Query: 997 XXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICA 1056 MP+ +++NA DT +GP LRA+W + L+ LW AL+ + Sbjct: 6472 DAPSATMPVASALDVNAVVGDTPDGPRLRATWAFPSGVLAAVDVGELADLWVRALSALAR 6531 Query: 1057 H-VRGGGGGLTPSDVAPARLTQRQIDELSQRY-DVTDVLPLTPVQQGLLFHSTFARGIGD 1114 H G GGLTPSD+ RL Q I+ L RY + DV L+P+Q GL FH+ A Sbjct: 6532 HAAHPGAGGLTPSDLDLVRLDQDAIEALEHRYPGLDDVWSLSPLQAGLHFHAMLADD-SV 6590 Query: 1115 DVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGE-----PVQVLTADPMI 1169 D Y VQL +++ G +D RL A ++ RHPNL A FV G VQV+ + Sbjct: 6591 DAYLVQLTLSLGGTVDTDRLWRAGQALLDRHPNLRAAFVRVEGAASDSGAVQVIPDRVEL 6650 Query: 1170 AWRYLDL-RGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHI 1228 W +DL R D T ++L AA+R DL P R L++ +R V+T HHI Sbjct: 6651 PWTEVDLSRLDPGTRARRFDELIAADRGTRFDLTAAPAIRMTLVKFGAGDYRLVVTNHHI 6710 Query: 1229 VIDGWSLPILLQEIFAGYF----GHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFE 1284 ++DGWS P++++++ Y LP PYR+++ W+ WR+ L G E Sbjct: 6711 LLDGWSTPLVIRDLLTLYATDADASVLPRVHPYRDYLAWMATQDPAESTDAWRKALAGLE 6770 Query: 1285 TPTLVAP--PGVPGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQ 1342 PTL+AP P G ++AE T L L R + T+NTV+QAAW +L +T + Sbjct: 6771 EPTLLAPAVPRAGGGTAELEVALTAEHTDTLRSLVRERGLTLNTVVQAAWGIVLGALTAR 6830 Query: 1343 RDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHE 1402 DV FG VSGRP + G ESMVGL INT+P+R + A T+G+LL ++Q L+H Sbjct: 6831 TDVLFGGTVSGRPPQIPGIESMVGLFINTLPVRVTLDAGETLGELLDRVQREQAALLDHH 6890 Query: 1403 HLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELA---VTEFNNREYNHYPLSVM 1459 +L L DI +G FDTL ++ESYP+D +A ++A VT + R+ HYPLS++ Sbjct: 6891 YLGLADIQRATGPAATFDTLTVFESYPVDRNALTADTDIAGLKVTGIDGRDAAHYPLSLV 6950 Query: 1460 ALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLD 1519 A L L+ EY VFD +E++ R +LE + DP R L+ +D++ D ER L Sbjct: 6951 ASVNGSLNLKFEYFPEVFDPDVVESIATRVTVVLEHIATDPDRPLARLDLLTDTERHDL- 7009 Query: 1520 EWANRAVLTQPV-DSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLA 1578 A + PV S +++P++F DP+A A++F G + Y ELD ++++A +L Sbjct: 7010 -----APVEGPVGGSIRTLPDIFTDAAALDPDAIALSFSGREVTYRELDTRSSRIARVLI 7064 Query: 1579 VYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVT 1638 G P VAL +PRS ++++A+ AV KTGAA++PIDP+ P R+E ML D+ +T Sbjct: 7065 DQGVGPESYVALGIPRSVESVLAVWAVTKTGAAFVPIDPNYPPERIEHMLADSGAGLGLT 7124 Query: 1639 TGDLRSRFDGFDLQVVEVDDPAVEI-------YPSTTLLTPSP---DDIAYMIYTSGTTG 1688 R R + ++DP V P T +P + AY++YTSG+TG Sbjct: 7125 VAAHRHRLPD-TATWLTLEDPDVAAACAAHSDAPVTDTDRTAPLGLEHAAYVVYTSGSTG 7183 Query: 1689 VPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVP 1748 PKGV + H + A A + + + FD +V+E A G +VI Sbjct: 7184 RPKGVVVAHRGLDNFALDQQARFGATATSRTLHFATPSFDGAVFEYLQAFGVGATMVIAE 7243 Query: 1749 ESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL-EGTALVVAGEACPTEVVDRWAV 1807 ++ G DL +L V + T +A+ + P GL E T + V GEACP E+V RWA Sbjct: 7244 PTVFGGA-DLARVLADGHVTHAFVTTAALATVDPTGLDEFTHVAVGGEACPPELVARWAP 7302 Query: 1808 DRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELY 1867 R + NAYGPTE+TI + ISAP++ G + IG P+ VLD L+PVP GV GELY Sbjct: 7303 GRDLHNAYGPTETTIMSNISAPMTVGEQIT-IGGPIRGVHEVVLDGRLQPVPVGVPGELY 7361 Query: 1868 LAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKI 1927 +A L+ RFVA PFG+PG RMYRTGD+VRW D ++Y+GR+D QVK+ Sbjct: 7362 IAGLGLARGYHRRPGLSAERFVANPFGKPGERMYRTGDIVRWRPDLTIEYVGRSDFQVKV 7421 Query: 1928 RGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTN 1983 RG+RIELGEI AAL+ V AV + GD L Y+ T + A L+ Sbjct: 7422 RGFRIELGEIDAALAADPTVGFAVTLGVPGPAGDTVLASYVVATTGATVETGALLDRLSE 7481 Query: 1984 RLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ-SAQRYRAPETETEKTLAGIFAHV 2042 +LP++MVPAAV L+ +PLT GKLDR ALP PE+ ++ +RAP E TL+ +F V Sbjct: 7482 QLPSHMVPAAVTVLDEIPLTPVGKLDRAALPEPEFAFTSGEFRAPTNPLEYTLSDVFTEV 7541 Query: 2043 LGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 LGV+R A RVTA ++ LDAD+ VR LFEAPT+ L+ V + G Sbjct: 7542 LGVDRIGIDDSFFDLGGNSLIATRVTARLSGLLDADIPVRALFEAPTIHALAQWVARERG 7601 Query: 2103 ERT 2105 T Sbjct: 7602 AGT 7604 Score = 1328 bits (3437), Expect = 0.0 Identities = 861/2178 (39%), Positives = 1182/2178 (54%), Gaps = 123/2178 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+P+ R + DLL DE I A G T+P L A V PDA A+ Sbjct: 2836 VTADPAVR-VGDVDLLTADERAAIAPVSGGA-----GVPARTLPELLATAGVVDPDATAV 2889 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V R +YR+LD S+RLA +L G P + VA + RS E++ + +V KTGAA++P Sbjct: 2890 VFEGRELSYRQLDADSDRLARLLIARGLGPESVVALALARSLESVTATWAVAKTGAAFVP 2949 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQY-DLAVIDMADPAIDRRPSDALSGP- 178 VDP +P RI M++D+ V LT R L + V+D D A+ R GP Sbjct: 2950 VDPNYPADRIEHMLTDSGAVVGLTVHGHRDALPPVTEWLVLD--DSAVRDRMQRQPGGPV 3007 Query: 179 ---------RPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWH 229 R DD AY+ YTSG+TG+PK V V+H + + P + Sbjct: 3008 TDADRVRPVRLDDPAYLIYTSGSTGIPKGVVVSHRGLANFAAEERTRFGITPRSRTLHFS 3067 Query: 230 SLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPE 289 S FD S+ E+ A+ G +VV P +V D+L +LL +V+ TP+A + P Sbjct: 3068 SPSFDASILELLLAVGSGATMVVAPPTVLGG-DELRDLLRENRVTHAFVTPAALASVDPA 3126 Query: 290 GLESTTLIVAG-EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXX 348 GL + + G EACP ELV +WAPGR M NAYGPTEAT+ A++SEPL Sbjct: 3127 GLTALECVATGGEACPPELVAQWAPGRRMFNAYGPTEATVVASISEPLAVGVPVTIGRPP 3186 Query: 349 XXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYR 408 L VLD L P P GV GELYV G G+A GY RP T RFVA PFG+ G RMYR Sbjct: 3187 LGTS-LVVLDARLHPVPAGVPGELYVLGSGLARGYHARPGTTGERFVANPFGDPGSRMYR 3245 Query: 409 TGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDK 468 TGDLVRW GQLEYLGR D QVK+RG+RIELGEI++AL + GV +AVV P Sbjct: 3246 TGDLVRWNGSGQLEYLGRTDFQVKVRGFRIELGEIESALRRFPGVARAVVTVDGSGPA-S 3304 Query: 469 RLVGYITGTA----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEY 524 RLVGY+ A DPA + + L +YMVP+AV+VLD +PL GKLDRRALPAP++ Sbjct: 3305 RLVGYVVPEAGAAVDPADVTEFVGTFLASYMVPSAVMVLDALPLGPAGKLDRRALPAPDF 3364 Query: 525 RSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQ 584 A RAP + E+ LAD++A+VLG++ VGVDDSFF LGGDSI+S+Q+V+RA++AG+ Sbjct: 3365 -GARTAGRAPRSERERQLADLFAEVLGLDSVGVDDSFFGLGGDSIMSIQLVSRAKSAGLH 3423 Query: 585 CRPRDIFVEQTXXXXXXXXXXXXESHVVDE----GVGPVVATPIMRWLREVDGPTGQFNQ 640 PRD+F +T ++ + E GVG V P+ WL + G +F+Q Sbjct: 3424 FTPRDVFEHKTVEALARVAQSGADTATLAELDGGGVGDVPLLPVAHWLLDRGGHHDRFSQ 3483 Query: 641 TVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR 700 + AP G+ + + +QA+LDRH LR R+ E ++VP AG+V A +R Sbjct: 3484 AALLTAPEGLDDASLTGAVQAVLDRHDMLRARIR-----PGEHRMIVPPAGSVYAEWLIR 3538 Query: 701 TV--------DALTDDVLVE---ARNRLDPAAGAMVSAVWVRETS---QLVLMIHHLAVD 746 + DA D V E A +RLDP+AG M+ VW+ S +L++++HHL VD Sbjct: 3539 RIRVDAAPGTDAFADTVRAELDAAEDRLDPSAGEMMQVVWLESASGGGRLLIVVHHLVVD 3598 Query: 747 GVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVT 806 GVSWRIL+ DL AWAQ G+ + GTS RW+ L + A RD + WRA+ Sbjct: 3599 GVSWRILVPDLATAWAQIVAGERPDPAPVGTSMRRWAHGLVDAAADR--RDELELWRAML 3656 Query: 807 SVPQAL---PPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA 863 S L P+ P D TA ++ + + T LL VP AFR V D LL A +A Sbjct: 3657 SGDDPLLGARPLDPAVDVASTARTVTVEVSPDVTDALLTTVPDAFRGSVNDGLLTALAMA 3716 Query: 864 WTEFLN----RSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQV 919 + +DT + V +EGHGR D + DL+RTVGWFTT +P+ L + + + Sbjct: 3717 LVRWRRDHGVDADTAL-VTLEGHGREDHVLPGADLARTVGWFTTLFPIRLDLTGIDIDDA 3775 Query: 920 VAGDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPE---VDLGGSDPTIGFNYLGRLGA 975 G G VKAVKEQL ++P+ G+ YG+LRYL+ E G + + FNYLGRL A Sbjct: 3776 FTGGRGAGAAVKAVKEQLLAVPDHGIGYGMLRYLDDEGGRALRGLASAQVSFNYLGRLTA 3835 Query: 976 GAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAF 1035 E + +P+ +++NA T D +G LRA+W + Sbjct: 3836 AVPEDQRAAGWV-PTDDADLSVLQDADLPVASVLDINAVTTDGADGSRLRATWGFPAGVL 3894 Query: 1036 DEEQATRLSRLWFEALAGICAHV-RGGGGGLTPSDVAPARLTQRQIDELSQRY-DVTDVL 1093 T L+ LW EAL + HV R G GGL+PSD+ L Q +I+ L QR+ ++ DV Sbjct: 3895 TAADVTELAGLWTEALIALARHVSRPGAGGLSPSDLDLVDLGQPEIETLEQRFPNLADVW 3954 Query: 1094 PLTPVQQGLLFHSTFA-RGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 L+P+Q GLLFH+ A R + D Y VQ+ + + G D RLR A ++ RHPNL + F Sbjct: 3955 SLSPLQSGLLFHAQLADRSV--DAYLVQMMLDVRGA-DPGRLRRAGQAMLDRHPNLRSAF 4011 Query: 1153 VE-QFGEPVQVLTADPMIAWRYLDL-RGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 V G PVQV+ + W +DL D+ + E+ +L A +R+ D+ E P R Sbjct: 4012 VHGPDGTPVQVVQERVPLPWNEIDLSEHDEPVREAELARLIADDRTRRFDMAEAPLIRFL 4071 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHR----LPAAAPYRNFVNWLXX 1266 L+RT ++HR +LT HHI++DGWS P+++QE+ Y LP YR+++ W+ Sbjct: 4072 LVRTGPDEHRLILTNHHILLDGWSTPLMMQELLTLYATDGDTTVLPRVHAYRDYLAWIAA 4131 Query: 1267 XXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAE--------TTRALGELAR 1318 W L G + PTL+AP RG E V AE T L + R Sbjct: 4132 QDPEAGVRAWTRSLAGLDEPTLLAPL----DRGREQATVPAEIDISLDVTRTARLQSIGR 4187 Query: 1319 SQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKV 1378 T+NT++QAAW +L TG+ DV FG VSGRP + G ESM+GL INT+P+R ++ Sbjct: 4188 QWGVTLNTMVQAAWAIVLGASTGRDDVVFGGTVSGRPPHIPGIESMIGLFINTLPVRVRL 4247 Query: 1379 SADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSA---- 1434 A +VG+LLR++QS L+H H++L DI G FDTL ++ESYP+D SA Sbjct: 4248 DARESVGELLRRIQSEQAGLLDHHHVSLTDIQDAVGPALAFDTLTVFESYPVDRSAITDA 4307 Query: 1435 -FMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLL 1493 G++ + V E + HYPL+++A L +++++ +FD + +L +R QR+L Sbjct: 4308 DISGLRLVRVHE--GSDAAHYPLTLVANADDRLRMKLKFLPDLFDRGQARSLAERVQRVL 4365 Query: 1494 EAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLT-QPVDSPQSIPEVFARQVERDPEAP 1552 M +DP L+ + ++ D EWA L +P S +++P++F DP+A Sbjct: 4366 VEMSEDPQCPLARLRLLSD------AEWAELVPLRGRPGRSVRTLPQLFTDAAAADPDAI 4419 Query: 1553 AVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAY 1612 A+ + Y ELDE +N+LA +L G P VAL +PRS D++VA+ AV KTGAA+ Sbjct: 4420 ALVAGTTEVTYRELDERSNRLARVLLDDGVGPESFVALGIPRSIDSVVAVWAVAKTGAAF 4479 Query: 1613 LPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTP 1672 LP+DP+ PA R+ FML D+ A +T R R + +DDPA E + P Sbjct: 4480 LPVDPNYPAERIAFMLEDSGATAGLTVTGARDRLPA-TVPWTVLDDPAFESRRAAQSAAP 4538 Query: 1673 SPDD----------IAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQW 1722 DD AY+IYTSGTTG PKGV +TH + + + P + + Sbjct: 4539 VGDDERPVPLRLTHPAYVIYTSGTTGTPKGVVVTHEGLDNLSEEYLTHFATRPSSRTLHF 4598 Query: 1723 HSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSP 1782 + FD +V + A +VI P S+ G +L L+ + V + T +A + P Sbjct: 4599 STPSFDAAVLDYLLAFGPAATMVIAPTSVYGG-SELADLIRDQHVTHAFITTAAAATVDP 4657 Query: 1783 EGL-EGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGS 1841 GL E T ++V GEA P E+V RWA R N YGPTE+T+ A +SAPL G + V IG+ Sbjct: 4658 AGLDEFTEVMVGGEAVPPELVARWAHGRRFYNGYGPTEATVMANVSAPLVTG-ETVTIGA 4716 Query: 1842 PVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMY 1901 P+ + VLD LRPVP GV GELY+A LT RFVA P G PG RMY Sbjct: 4717 PLRGVSELVLDTNLRPVPAGVPGELYIAGPNLARGYHRRPGLTAERFVANPHGVPGERMY 4776 Query: 1902 RTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGD 1961 RTGD+VR D ++Y+GR+D QVKIRG+RIELG+I A D + AV + R G+ Sbjct: 4777 RTGDVVRVLADRTIEYVGRSDFQVKIRGFRIELGDIDNAFGDHPDIRFAVTLGRPGPTGE 4836 Query: 1962 KRLVGYITGTA----DPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPE 2017 LV Y+ A +P A R + LPA MVPA+++ L+ +PLT GKLDR ALPAPE Sbjct: 4837 TSLVTYVLPVAGAQPEPGALREYVAEHLPAQMVPASIMILDEIPLTPIGKLDRAALPAPE 4896 Query: 2018 Y-QSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALD 2076 + +A +RAP TE+T+ F VLG+ER A RV A + AL Sbjct: 4897 FLPAATTFRAPTDPTEQTIVDTFTAVLGLERIGVDDSFFDLGGNSLIATRVIARLGAALG 4956 Query: 2077 ADLSVRTLFEAPTVAKLS 2094 DL VR LFEAPT +L+ Sbjct: 4957 VDLGVRALFEAPTAHELA 4974 Score = 542 bits (1396), Expect = e-151 Identities = 390/1093 (35%), Positives = 540/1093 (49%), Gaps = 99/1093 (9%) Query: 1088 DVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPN 1147 D D LPL+ Q+ + F + F Y + L + +TG LD L AV V RH Sbjct: 4994 DRPDPLPLSLAQKRMWFINQF--DTESAAYNIPLAVRLTGDLDVAALTAAVADVQERHET 5051 Query: 1148 LAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTF 1207 L F + GEPVQ++ A L D+ PD E++ AA S D+ Sbjct: 5052 LRTLFPSRDGEPVQLVVPAAEAA---PSLDAVDVPPDRVPERI-AALISRGFDVTTAVPV 5107 Query: 1208 RAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYF---GHRLPAAAP----YRNF 1260 RA L+R +H + HHI DG+S+ L +++ A Y G +P AP Y +F Sbjct: 5108 RAELLRLGPREHVLTIVVHHICADGFSMAPLARDVMAAYVARTGGHVPQWAPLPVQYADF 5167 Query: 1261 VNWLXXXXXXXXXXX---------WREVLDGF-ETPTLVAPPGVPGPRGIESYRVS---- 1306 W W E L G E TL P + + RV Sbjct: 5168 ALWQHQVLGSEDDPDSPGRRQLAFWTEALAGLPEAITLPTDRPRPSRQSFDGARVEFEIP 5227 Query: 1307 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVG 1366 AE RAL E AR T+ AA LL +++G D+A GT ++GR A + +VG Sbjct: 5228 AEVHRALAESARRHGATMFMATHAALAVLLAKLSGTDDIAIGTPIAGRGE--AELDDLVG 5285 Query: 1367 LLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHV------SGHEQLFD 1420 + +NT+ +R+ V DLL + + H L + V + H LF Sbjct: 5286 MFVNTLVLRSDVDPAGGFADLLARTREFDLAAFGHADLPFERLVDVLAPERSTAHSPLFQ 5345 Query: 1421 TLFLYESYPIDTSAFMGV------QELAVTEFNNREYNHYPLSVMALPGHE-------LG 1467 + +++ + G+ +LAV +F+ L + H+ + Sbjct: 5346 VMLEFQNNELPRLELPGLVADPVAADLAVAKFD--------LQLTLAERHDDAGVPDGIA 5397 Query: 1468 LRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVL 1527 Y T +FD + L +RF RLL+A++ +P R + + + T+LD +R Sbjct: 5398 AVFTYATDLFDPGTVRELGERFTRLLDALVAEPERAIGDITITT---ATELDTMLHRWNA 5454 Query: 1528 TQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 + +++ + FA R P+ PA+T+E +L Y ELD AN+LA L G P Sbjct: 5455 EGARAADETLADRFALAAARFPDRPALTYEASTLGYAELDARANRLARHLVSLGVGPETL 5514 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VA+ +PRSAD +VA+LAV+K+GA YLP+D + PA RL +ML DA PV +TTG + Sbjct: 5515 VAVALPRSADLVVALLAVIKSGAGYLPLDVTYPAERLSYMLTDAAPVCVLTTGADANAIP 5574 Query: 1648 GFDLQVVEVDD----PAVEIYPSTTL-----LTP-SPDDIAYMIYTSGTTGVPKGVAITH 1697 D+ ++ +D A+ P + LTP PDD+AY+IYTSG+TG PKGV +TH Sbjct: 5575 STDVPLIRLDTDETAAALAAAPDRAVTDADRLTPLRPDDVAYVIYTSGSTGRPKGVQVTH 5634 Query: 1698 GNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDD 1757 NV + VW+ +HS FD SVWE+WG LLHGGRLV+V A SP+ Sbjct: 5635 RNVLTLFANTTGAFGFDEHDVWTMFHSYAFDFSVWELWGPLLHGGRLVVVDFYTARSPEM 5694 Query: 1758 LHALLVSEGVNVLYQTPSAV-------RMMSPEGLEGTAL-----VVAGEACPTEVVDRW 1805 LL +E V VL QTP+A R+ S +G T L V GEA + RW Sbjct: 5695 FLDLLRTEQVTVLNQTPTAFYQLAEADRLASEQGTTATDLALRYVVFGGEALDLGQLGRW 5754 Query: 1806 AVDRV-----MINAYGPTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRP 1857 ++N YG TE+T++ + + +D IG +P VLDE L Sbjct: 5755 YTRHPDSAPRLVNMYGITETTVHVTHLELDRAFAEAADASVIGRAIPGLRVVVLDERLHS 5814 Query: 1858 VPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQY 1917 VPPGVVGE+Y+A LT +RFVA PFG PG+RMYRTGDL RW DG+L+Y Sbjct: 5815 VPPGVVGEMYVAGEQLTRGYLGRSALTSSRFVADPFGAPGSRMYRTGDLARWNRDGRLEY 5874 Query: 1918 LGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITG----TAD 1973 LGR+D QVKIRG+RIELGEI+AAL GV QAVV D G RLVGY D Sbjct: 5875 LGRSDFQVKIRGFRIELGEIEAALLRYPGVAQAVVAVHRDGTGPARLVGYAVPEQGLDVD 5934 Query: 1974 PAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETE 2032 P + L +YMVPA ++ L+ LPLT NGKLDR+ALP PE+ A R RAPET+ E Sbjct: 5935 PQDVLGHVGRELTSYMVPATLMLLDELPLTANGKLDRKALPQPEFGTGAARGRAPETDVE 5994 Query: 2033 KTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADL--SVRTLFEAPTV 2090 +TLAG+FA VLG++ ++++ V+ A DA L + R +FE +V Sbjct: 5995 RTLAGLFAEVLGLDSVGVDDSFFGLGGDSIMSIQL---VSRAKDAGLRFTPRDVFEHRSV 6051 Query: 2091 AKLSLHVEHDAGE 2103 A L+ D+GE Sbjct: 6052 AGLAAVAAADSGE 6064 Score = 501 bits (1289), Expect = e-139 Identities = 369/1122 (32%), Positives = 540/1122 (48%), Gaps = 119/1122 (10%) Query: 1050 ALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFA 1109 ALA A RG G G T ++ R + D +PL+ QQ + F + F Sbjct: 7591 ALAQWVARERGAGTGHTRPELG--------------RRERPDRIPLSLAQQRMWFINQF- 7635 Query: 1110 RGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMI 1169 Y + + + +TG LD LRDAV V+ RH +L + EP Q + Sbjct: 7636 -DTASAAYNIPMAVNLTGALDTGALRDAVGDVLERHESLRTAYPIVDQEPTQEV------ 7688 Query: 1170 AWRYLDLRGDDLTP-----DHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLT 1224 W D+ DLTP D E+ + A S D+ P RA L+ H V+ Sbjct: 7689 -WPVGDVL-TDLTPVPVDDDAELRRQITAFASHGFDVTAAPPVRAELLEIDDEHHVLVIV 7746 Query: 1225 FHHIVIDGWSLPILLQEIFAGYFGHR-------LPAAAPYRNFVNWL---------XXXX 1268 HHI DG+S+ L +++ A Y P Y ++ W Sbjct: 7747 VHHICADGYSMAPLGRDLMAAYTARAAGTSPQWAPLPVQYADYTLWQHEMLGTDTDPDSL 7806 Query: 1269 XXXXXXXWREVLDGFETPTLVAPPGVPGP------RGIESYRVSAETTRALGELARSQHT 1322 W E L G + P P P G +RV AE + ELA Sbjct: 7807 ISRQLRFWTEELAGL-PDVIQLPTDRPRPVQQTFRGGRVEFRVPAELHTRITELAHRHGA 7865 Query: 1323 TINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADT 1382 ++ + AA +L R+ D+A GT ++GR ++A + +VG+ +NT+ +R ++ DT Sbjct: 7866 SMFMAMHAALATVLARLADTDDIAIGTPIAGR-GEMA-LDELVGMFVNTLVLRTRIDHDT 7923 Query: 1383 TVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELA 1442 + LL+Q++ E + A GH ++ + E P ++++ + +++ Sbjct: 7924 SFDALLQQVR-------ESDLAAF-------GHAEVPFERLVEEINPPRSTSYSPLFQVS 7969 Query: 1443 VTEFNNREYNHYPLSVMALPGHELGLRV--------------------------EYDTSV 1476 + EF N E L + + G + +V ++ T + Sbjct: 7970 I-EFQNNERPRLELPGLTVEGVGIDAQVAKEDLELVLAEEFTDTGDPAGVLASLDFATDL 8028 Query: 1477 FDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQS 1536 FD S + + RF R+LEA++ DPAR + ++++D E L + + SP Sbjct: 8029 FDESTVRGIAHRFIRVLEAVVADPARAVGDIEILDSGELAALAPAHGGSDV-----SPHV 8083 Query: 1537 IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSA 1596 PE+ DP+A A+++ G +L Y +LDE +N+LA +LA G P VAL +PRS Sbjct: 8084 WPELLESAAAVDPDAVALSYLGRTLTYRQLDERSNRLARVLAGRGVGPETFVALGMPRSI 8143 Query: 1597 DAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEV 1656 D IV+I AV K+GAA++P+DP+ PA R+ ML D+ +TT LR R + + + Sbjct: 8144 DEIVSIWAVAKSGAAFVPVDPNYPAERIAHMLTDSGTRLGLTTSALRERLPD-TVPWLVL 8202 Query: 1657 DDPAVEIYPSTTLLTPSPD----------DIAYMIYTSGTTGVPKGVAITHGNVTQVLDT 1706 DD A+ + P D AY+IYTSG+TG PKGV +TH + + + Sbjct: 8203 DDDAIAARLADASPAPVTDADRTAPLHLTHPAYLIYTSGSTGRPKGVIVTHLGIANLTEE 8262 Query: 1707 LPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEG 1766 P A S S FD SV+E+ A G RLVIVP ++ G +L LL EG Sbjct: 8263 ERQRFSVTPDARVSHLASPSFDASVFEMMMAFSAGARLVIVPPTVYGGA-ELTDLLSREG 8321 Query: 1767 VNVLYQTPSAVRMMSPEGLEG-TALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAA 1825 V + TP+A+ + EGLE L VAGEACP E+V +WA R M N YGPTE+TI A+ Sbjct: 8322 VTHGFITPTALASIEDEGLESLRILAVAGEACPPELVAKWAPGRRMFNGYGPTETTIQAS 8381 Query: 1826 ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTG 1885 +SAP+ PG + V IG P VLD LRPVP GV GELY++ LT Sbjct: 8382 VSAPMQPG-ETVNIGGPAIGFEEAVLDGRLRPVPVGVPGELYISGPGLARGYHNRPGLTA 8440 Query: 1886 TRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVD 1945 RFVA PFG PG+RMYRTGD+VRW D ++Y+GR+D QVK+RG+RIELGEI A L+ Sbjct: 8441 ERFVANPFGPPGSRMYRTGDVVRWRHDDTIEYIGRSDFQVKVRGFRIELGEIDAVLTRHP 8500 Query: 1946 GVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSELTNRLPAYMVPAAVVTLETLP 2001 + A + GD L Y+ + + R+ + +LPA+MVP+AVV L+ +P Sbjct: 8501 AITFAATLGHTGPSGDTLLASYVRPVEGHSVEARELRAHVAAQLPAHMVPSAVVVLDEIP 8560 Query: 2002 LTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXX 2060 LT GKLDRRALP PE+ S +R P T TE+ + +FA VLGV+ Sbjct: 8561 LTPVGKLDRRALPTPEFTSLTTEFRPPSTATERAVTEVFADVLGVDHVGIDDSFFDLGGN 8620 Query: 2061 XXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 A R+ + + L L ++T+F PT + L+ ++ G Sbjct: 8621 SIIATRIMSELQARLGRQLPLQTMFLDPTPSGLAKRIDLPVG 8662 Score = 498 bits (1281), Expect = e-138 Identities = 377/1127 (33%), Positives = 538/1127 (47%), Gaps = 92/1127 (8%) Query: 1048 FEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHST 1107 F+A +R GG+ + AP +R +P++ Q+ + F + Sbjct: 2375 FDAPTVAALALRIESGGMRGPERAPLEPAERPA-----------AVPVSLAQKRMWFINQ 2423 Query: 1108 FARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADP 1167 F Y V L + + G LD+ LR AV V+ RH +L RF GEPVQV+ Sbjct: 2424 F--DTSSAAYNVVLPVRLDGDLDRGALRAAVADVLDRHESLRTRFPMIDGEPVQVIVPTA 2481 Query: 1168 MIAWRYLDLRGDDLTPDHEIEQLCAAERSAV-----CDLLERPTFRAALIRTSGNQHRFV 1222 +A DL P+ EQ AER A D+ P R+ L+R H V Sbjct: 2482 AVA--------PDLEPESVAEQ-DVAERVAEFAGRGFDVTVAPPVRSLLLRVGPQTHVLV 2532 Query: 1223 LTFHHIVIDGWSLPILLQEIFAGYFG-------HRLPAAAPYRNFVNWL---------XX 1266 + HHI DG+SL L +++ + Y H P A Y ++ W Sbjct: 2533 IVVHHICADGFSLAPLARDVMSAYIARTEDRAPHWTPLAVQYADYALWQQKVLGGTDDPD 2592 Query: 1267 XXXXXXXXXWREVLDG----FETPTLVAPPGVPGPRG-IESYRVSAETTRALGELARSQH 1321 W LDG + PT P RG + +R+ + R L +AR+ + Sbjct: 2593 SVLSRQLEYWARTLDGLPEVLDLPTDRPRPSERTLRGAVHGFRLGPDVHRRLTAVARTHN 2652 Query: 1322 TTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSAD 1381 T+ + AA LL R+ DVA GT ++GR A A + MVG+ +NT+ +R+ Sbjct: 2653 ATVFMAVHAALAALLARLGDTDDVAIGTPIAGRGA--AALDDMVGMFVNTLVLRSHFDPA 2710 Query: 1382 TTVGDLLR-----QLQSHHNDTLEHEHL--ALNDIHHVSGHEQLFDTLFLYESYPIDTSA 1434 T +LL L + HN L E L AL + H LF + + + Sbjct: 2711 ATYSELLAAVRDGDLDAFHNADLPFERLVDALAP-ERSTAHSPLFQVMLEFRNNEQPRLE 2769 Query: 1435 FMGVQELAV---TEFNNREYNHYPLSVMALPGHELGLRV--EYDTSVFDVSEIETLIDRF 1489 G+ V T+ N + G G+ Y T +FD + + L +RF Sbjct: 2770 LPGLTVTLVDTGTDSTNFDLQLTLTEEFTESGEPAGVAAGFTYATDLFDPATVTRLAERF 2829 Query: 1490 QRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDP 1549 +L A+ DPA R+ +D++ DER + + A + +++PE+ A DP Sbjct: 2830 GAVLRAVTADPAVRVGDVDLLTADERAAIAPVSGGAGV-----PARTLPELLATAGVVDP 2884 Query: 1550 EAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTG 1609 +A AV FEG L+Y +LD +++LA LL G P VAL + RS +++ A AV KTG Sbjct: 2885 DATAVVFEGRELSYRQLDADSDRLARLLIARGLGPESVVALALARSLESVTATWAVAKTG 2944 Query: 1610 AAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVE------- 1662 AA++P+DP+ PA R+E ML D+ V +T R +V +DD AV Sbjct: 2945 AAFVPVDPNYPADRIEHMLTDSGAVVGLTVHGHRDALPPVTEWLV-LDDSAVRDRMQRQP 3003 Query: 1663 ---IYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVW 1719 + + + DD AY+IYTSG+TG+PKGV ++H + P + Sbjct: 3004 GGPVTDADRVRPVRLDDPAYLIYTSGSTGIPKGVVVSHRGLANFAAEERTRFGITPRSRT 3063 Query: 1720 SQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRM 1779 + S FD S+ E+ A+ G +V+ P ++ G D+L LL V + TP+A+ Sbjct: 3064 LHFSSPSFDASILELLLAVGSGATMVVAPPTVLGG-DELRDLLRENRVTHAFVTPAALAS 3122 Query: 1780 MSPEGLEGTALV-VAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVP 1838 + P GL V GEACP E+V +WA R M NAYGPTE+T+ A+IS PL+ G V Sbjct: 3123 VDPAGLTALECVATGGEACPPELVAQWAPGRRMFNAYGPTEATVVASISEPLAVGVPVT- 3181 Query: 1839 IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGA 1898 IG P + VLD L PVP GV GELY+ TG RFVA PFG+PG+ Sbjct: 3182 IGRPPLGTSLVVLDARLHPVPAGVPGELYVLGSGLARGYHARPGTTGERFVANPFGDPGS 3241 Query: 1899 RMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDR 1958 RMYRTGDLVRW GQL+YLGR D QVK+RG+RIELGEI++AL GV +AVV Sbjct: 3242 RMYRTGDLVRWNGSGQLEYLGRTDFQVKVRGFRIELGEIESALRRFPGVARAVVTVDGSG 3301 Query: 1959 PGDKRLVGYITGTA----DPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALP 2014 P RLVGY+ A DPA + L +YMVP+AV+ L+ LPL GKLDRRALP Sbjct: 3302 PA-SRLVGYVVPEAGAAVDPADVTEFVGTFLASYMVPSAVMVLDALPLGPAGKLDRRALP 3360 Query: 2015 APEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTA 2074 AP++ + RAP +E E+ LA +FA VLG++ ++++ + +A Sbjct: 3361 APDFGARTAGRAPRSERERQLADLFAEVLGLDSVGVDDSFFGLGGDSIMSIQLVSRAKSA 3420 Query: 2075 LDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAAVHGSDVTEV 2121 + R +FE TV L+ + A D + A + G V +V Sbjct: 3421 -GLHFTPRDVFEHKTVEALARVAQSGA----DTATLAELDGGGVGDV 3462 Score = 469 bits (1206), Expect = e-129 Identities = 360/1079 (33%), Positives = 503/1079 (46%), Gaps = 91/1079 (8%) Query: 1088 DVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPN 1147 D T +P++ QQ + F + A G Y + + + ++G LD LR A+ VV RH Sbjct: 1333 DHTGPVPVSLAQQRMWFVNQLAPGSA--AYNIPIAVRLSGPLDVAALRGALADVVERHQT 1390 Query: 1148 LAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTF 1207 L F PVQ + + +A LDL +D+T + ++ Q +A D+ + Sbjct: 1391 LRTVFPNTSDGPVQQVRS---VADAALDLEPEDVT-ETQLPQRLQGVATAPFDVSVQLPV 1446 Query: 1208 RAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNF 1260 RA L R +H L HH+ DG S+ L +++ Y P A Y ++ Sbjct: 1447 RAHLWRLGPTEHVLALVAHHVAADGLSMAPLARDVMVAYGARAAGTEPAWPPLAVQYADY 1506 Query: 1261 VNWLXXXXXXXXXXX---------WREVLDG----FETPT-LVAPPGVPGPRGIESYRVS 1306 W WR+ L G E PT PP G S ++ Sbjct: 1507 AVWQRELLGAEDDPRSLAARQIAFWRDELTGAPDLLELPTDRPRPPQQSMRGGTVSCTIA 1566 Query: 1307 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVG 1366 R L E+A ++ VL AA LL R +G DV G+ VSGR A + +VG Sbjct: 1567 PHLHRRLLEVAGEYEASLFMVLHAALAVLLARASGATDVTIGSPVSGRGE--AELDDLVG 1624 Query: 1367 LLINTVPIRAKVSADTTVGDLLRQ-----LQSHHNDTLEHEHLA-LNDIHHVSGHEQLFD 1420 + +NT+ +R++V T DLL L + N + E L + D + LF Sbjct: 1625 MFVNTLVLRSRVDHGGTFSDLLAHTRTTDLAALGNTDVPFERLVEVLDPPRSEAYSPLFQ 1684 Query: 1421 TLFLYESYP---------------IDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHE 1465 + + + IDT ++ +TE ++ E P+ Sbjct: 1685 VMLVLQGSERNRLELPGLAVEVDEIDTGTAKFDLQVILTEQSDEEGRPGPIEAT------ 1738 Query: 1466 LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQ-LDEWANR 1524 + Y T +FD + L +R+ R+LEA+ DPA R+ +DV+ D ER LDEW N Sbjct: 1739 ----LSYATDLFDPDTVAALAERYLRILEAVSVDPAVRVGDIDVLVDGERELVLDEW-NA 1793 Query: 1525 AVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAP 1584 + P ++ ++F Q R P A A+TF E L Y E A +LA L G P Sbjct: 1794 TAHSVP---DATLTDLFDAQARRTPHAVALTFGDEQLTYAEFASRARRLARELIARGVGP 1850 Query: 1585 GKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRS 1644 VAL + RS D ++ + AV + G AY+P+DP PAAR E++L A P +TT R+ Sbjct: 1851 ESRVALSMRRSFDLLIGMYAVTEAGGAYVPLDPDHPAARTEYVLASAAPACVLTTRRDRA 1910 Query: 1645 RFDGFDLQVVEVDDPAVE------IYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHG 1698 D+ V+E+D + I P + PD +AY+IYTSG+TG PKGVA++H Sbjct: 1911 GLQT-DIDVLEIDSLDLAGRGDGPIRPEERVGALRPDHVAYVIYTSGSTGRPKGVAVSHR 1969 Query: 1699 NVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDL 1758 + L + V Q FDVSVWE + L +G L I P L Sbjct: 1970 AIVNRLAWMQDRYHLTGTDVVVQKTPATFDVSVWEFFWPLQNGASLAIALPEGHRDPAYL 2029 Query: 1759 HALLVSEGVNVLYQTPS--AVRMMSPEGLEGTAL---VVAGEACPTEVVDRWA-----VD 1808 L+ GV V + PS A ++ + ++ +L +GE P + +A Sbjct: 2030 SQLIHDRGVTVAHFVPSMLAAFVVGADPVQCRSLRTVFCSGEGLPPSTAEAFAEFVGPAG 2089 Query: 1809 RVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYL 1868 + N YGPTE+ + + + VPIG+PV +VLD L P P GV GELYL Sbjct: 2090 AELHNLYGPTEAAVDVTYRQYTAADTVSVPIGTPVWNTQVYVLDARLHPAPVGVPGELYL 2149 Query: 1869 AXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDG----QLQYLGRADEQ 1924 A LT RFVA PFG PG R+YRTGDLVRW G L YLGR D Q Sbjct: 2150 AGVQLARGYVGRPDLTAERFVANPFGAPGTRLYRTGDLVRWRKTGHLDYSLDYLGRTDFQ 2209 Query: 1925 VKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITG----TADPAAARSE 1980 VK+RG RIELGE++A L GV QAVV+ R D + LVGY+ +PAA R Sbjct: 2210 VKLRGLRIELGEVEATLLSRPGVAQAVVVVRRDELVGEALVGYVIADPGVELEPAALRES 2269 Query: 1981 LTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQ-RYRAPETETEKTLAGIF 2039 L LPAYMVP+ ++ L+ PL GKLDRRALPAPE+ S + + AP E+ LA IF Sbjct: 2270 LAESLPAYMVPSQILVLDEFPLGSTGKLDRRALPAPEFGSVEAEFVAPRGPVEEILALIF 2329 Query: 2040 AHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVE 2098 ++G R A R+ A VN ALDA + VR +F+APTVA L+L +E Sbjct: 2330 GELVGTTRIGVYDSFFDLGGNSLTATRLVARVNDALDAHIGVRDVFDAPTVAALALRIE 2388 Score = 431 bits (1107), Expect = e-117 Identities = 263/574 (45%), Positives = 338/574 (58%), Gaps = 21/574 (3%) Query: 39 TPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLI 98 +P P L PDAVAL R+ TYR+LDE SNRLA VLA G P VA + Sbjct: 8080 SPHVWPELLESAAAVDPDAVALSYLGRTLTYRQLDERSNRLARVLAGRGVGPETFVALGM 8139 Query: 99 PRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRL-DQYDL 157 PRS + I+SI +V K+GAA++PVDP +P RI M++D+ LTT+ LR RL D Sbjct: 8140 PRSIDEIVSIWAVAKSGAAFVPVDPNYPAERIAHMLTDSGTRLGLTTSALRERLPDTVPW 8199 Query: 158 AVIDMADPAIDRRPSDALSGPRPD----------DLAYMTYTSGTTGVPKAVAVTHHNVT 207 V+D D AI R +DA P D AY+ YTSG+TG PK V VTH + Sbjct: 8200 LVLD--DDAIAARLADASPAPVTDADRTAPLHLTHPAYLIYTSGSTGRPKGVIVTHLGIA 8257 Query: 208 QLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNL 267 L P S S FD SV+E+ A G RLV+VP +V + L +L Sbjct: 8258 NLTEEERQRFSVTPDARVSHLASPSFDASVFEMMMAFSAGARLVIVPPTVYGGAE-LTDL 8316 Query: 268 LITEKVSVLCQTPSAAGMLSPEGLESTTLI-VAGEACPTELVDRWAPGRVMINAYGPTEA 326 L E V+ TP+A + EGLES ++ VAGEACP ELV +WAPGR M N YGPTE Sbjct: 8317 LSREGVTHGFITPTALASIEDEGLESLRILAVAGEACPPELVAKWAPGRRMFNGYGPTET 8376 Query: 327 TIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGR 386 TI A++S P+ VLD LRP P GV GELY++G G+A GY R Sbjct: 8377 TIQASVSAPMQPGETVNIGGPAIGFEEA-VLDGRLRPVPVGVPGELYISGPGLARGYHNR 8435 Query: 387 PDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAA 446 P LTA RFVA PFG G RMYRTGD+VRW D +EY+GR+D QVK+RG+RIELGEI A Sbjct: 8436 PGLTAERFVANPFGPPGSRMYRTGDVVRWRHDDTIEYIGRSDFQVKVRGFRIELGEIDAV 8495 Query: 447 LAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVVV 502 L + + A + GD L Y+ + + +LR +A LPA+MVP+AVVV Sbjct: 8496 LTRHPAITFAATLGHTGPSGDTLLASYVRPVEGHSVEARELRAHVAAQLPAHMVPSAVVV 8555 Query: 503 LDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFF 562 LD IPLT GKLDRRALP PE+ S ++R PST E+ + +V+A VLGV+ VG+DDSFF Sbjct: 8556 LDEIPLTPVGKLDRRALPTPEFTSLTTEFRPPSTATERAVTEVFADVLGVDHVGIDDSFF 8615 Query: 563 DLGGDSILSMQVVARARA-AGIQCRPRDIFVEQT 595 DLGG+SI++ ++++ +A G Q + +F++ T Sbjct: 8616 DLGGNSIIATRIMSELQARLGRQLPLQTMFLDPT 8649 Score = 427 bits (1097), Expect = e-116 Identities = 305/856 (35%), Positives = 429/856 (50%), Gaps = 79/856 (9%) Query: 1295 PGPRGIESYRVSAETT----RALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTA 1350 P R + S RV E RA+ + ++ T+ + AA LL R+ DVA GT Sbjct: 489 PARRALASDRVDFEIPAAVHRAVVAQSEARGCTVFAAVHAALVVLLARLADVDDVAIGTP 548 Query: 1351 VSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQL------QSHHNDTLEHEHL 1404 V+GR S G +NT+ +R ++S T DLL + H +T + + Sbjct: 549 VTGR--------SPAGEFVNTLTLRTRLSPGLTFDDLLTDVCRADTAAFRHAETPFAQLV 600 Query: 1405 ALNDIHHVSGHEQLFDTLFLYES-------------YPIDTSAFMGVQELAVTE----FN 1447 D + H LF + + +DT + +L +T Sbjct: 601 ESLDRTRENAHSPLFQVMLEFHDGRTPHLDEDGLVVRGVDTGPDISALDLRLTVEERFAG 660 Query: 1448 NREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSM 1507 N + P V A + T +FD IETL RF R+L+A+++DP+ ++ + Sbjct: 661 NAAGDAVPDGVHA--------SFAFATDMFDPETIETLSARFLRVLDAVLEDPSTVVADI 712 Query: 1508 DVVDDDERTQLDE-WANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGEL 1566 D++ ++ER QL W V P+++ E+ A DP A+T+EG L+Y L Sbjct: 713 DLLSEEERRQLSGVWGGDGV------EPRTLAEILAAAAHTDPTRTALTYEGRQLSYRAL 766 Query: 1567 DEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEF 1626 DE +N+LA LL G P VAL +PRS +++ ++ AV KTGAA++P+DP+ PA R+E Sbjct: 767 DEDSNRLARLLVSRGVGPESVVALSMPRSIESVASVWAVAKTGAAFVPVDPNYPADRIEH 826 Query: 1627 MLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDP--AVEIYP-STTLLTPSP-------DD 1676 ML D+ A+T + + + VDDP +++ S +T + D+ Sbjct: 827 MLTDSGATLALTVAAHAAAVADI-VPALVVDDPGFGAQVHQWSPDSITDADRSAPVRIDN 885 Query: 1677 IAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWG 1736 AY+IYTSG+TG PKGV +TH + + P + + S FD SV E+ Sbjct: 886 PAYLIYTSGSTGTPKGVTVTHRGLANFAEDERRRYGVRPDSRTLHFSSPSFDASVLELML 945 Query: 1737 ALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL-EGTALVVAGE 1795 A G +VI P ++ G +L ALL E V + TP+A+ + + L E +V GE Sbjct: 946 AFGAGATMVIAPPTVYGGA-ELTALLRDERVTHAFVTPAALGSVDADALPELECVVTGGE 1004 Query: 1796 ACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWL 1855 ACP +V++WA M NAYGPTE+T+ +++S PL G DV IG P VLD L Sbjct: 1005 ACPPYLVEQWAPRHRMFNAYGPTEATVVSSVSDPLVVGQDVT-IGCPPIGTGVLVLDARL 1063 Query: 1856 RPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRW---GDD 1912 RPVPPGV GELY+ T RFVA PF G RMYRTGDLVRW G Sbjct: 1064 RPVPPGVAGELYVYGEGQARGYHARAGTTAERFVANPF--DGTRMYRTGDLVRWRRFGRR 1121 Query: 1913 GQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYI---- 1968 L+Y+GR D Q+KIRGYRIELGE++AAL V A+ GD LV Y+ Sbjct: 1122 HSLEYVGRTDFQIKIRGYRIELGEVEAALRSHPDVGFALATGFVGPSGDTLLVAYVQAES 1181 Query: 1969 ---TGTADPAAAR--SELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ-SAQ 2022 TG + A+ + + LP +MVPA+VV L++LPLT GKLDRRALP P + Sbjct: 1182 NRETGVGEHLASEVTAHAADVLPPHMVPASVVVLDSLPLTPAGKLDRRALPEPRFDVGTG 1241 Query: 2023 RYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVR 2082 + AP T EK +AG+F+ +LGVER A R+ A +N L +LSV Sbjct: 1242 EFHAPATLDEKKIAGVFSELLGVERIGTTDSFFDLGGNSLTATRIVARINATLGTELSVL 1301 Query: 2083 TLFEAPTVAKLSLHVE 2098 LFEAPTV L+ VE Sbjct: 1302 DLFEAPTVGALAARVE 1317 Score = 409 bits (1051), Expect = e-111 Identities = 327/948 (34%), Positives = 456/948 (48%), Gaps = 75/948 (7%) Query: 4 EPSTRTLLSFDLLDEDEHDQIE-VWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVS 62 +PST + DLL E+E Q+ VWG G P T+ + A P AL Sbjct: 704 DPST-VVADIDLLSEEERRQLSGVWGG------DGVEPRTLAEILAAAAHTDPTRTALTY 756 Query: 63 GDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVD 122 R +YR LDE SNRLA +L G P + VA +PRS E++ S+ +V KTGAA++PVD Sbjct: 757 EGRQLSYRALDEDSNRLARLLVSRGVGPESVVALSMPRSIESVASVWAVAKTGAAFVPVD 816 Query: 123 PAHPDARIGFMMSDAKPVAALTTADLRSRL-DQYDLAVIDMADPAIDRR----------P 171 P +P RI M++D+ ALT A + + D V+D DP + Sbjct: 817 PNYPADRIEHMLTDSGATLALTVAAHAAAVADIVPALVVD--DPGFGAQVHQWSPDSITD 874 Query: 172 SDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSL 231 +D + R D+ AY+ YTSG+TG PK V VTH + P + S Sbjct: 875 ADRSAPVRIDNPAYLIYTSGSTGTPKGVTVTHRGLANFAEDERRRYGVRPDSRTLHFSSP 934 Query: 232 VFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGL 291 FD SV E+ A G +V+ P +V + L LL E+V+ TP+A G + + L Sbjct: 935 SFDASVLELMLAFGAGATMVIAPPTVYGGAE-LTALLRDERVTHAFVTPAALGSVDADAL 993 Query: 292 -ESTTLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXX 350 E ++ GEACP LV++WAP M NAYGPTEAT+ +++S+PL Sbjct: 994 PELECVVTGGEACPPYLVEQWAPRHRMFNAYGPTEATVVSSVSDPLVVGQDVTIGCPPIG 1053 Query: 351 XXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTG 410 L VLD LRP P GV GELYV G G A GY R TA RFVA PF G RMYRTG Sbjct: 1054 TGVL-VLDARLRPVPPGVAGELYVYGEGQARGYHARAGTTAERFVANPFD--GTRMYRTG 1110 Query: 411 DLVRWGSDGQ---LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGD 467 DLVRW G+ LEY+GR D Q+KIRGYRIELGE++AAL V A+ GD Sbjct: 1111 DLVRWRRFGRRHSLEYVGRTDFQIKIRGYRIELGEVEAALRSHPDVGFALATGFVGPSGD 1170 Query: 468 KRLVGYI-------TGTAD--PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRA 518 LV Y+ TG + +++ A+ LP +MVP +VVVLD++PLT GKLDRRA Sbjct: 1171 TLLVAYVQAESNRETGVGEHLASEVTAHAADVLPPHMVPASVVVLDSLPLTPAGKLDRRA 1230 Query: 519 LPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARA 578 LP P + ++ AP+T E+ +A V++++LGVER+G DSFFDLGG+S+ + ++VAR Sbjct: 1231 LPEPRFDVGTGEFHAPATLDEKKIAGVFSELLGVERIGTTDSFFDLGGNSLTATRIVARI 1290 Query: 579 RAA-GIQCRPRDIFVEQTXXXXXXXXXXXXESH------VVDEGVGPV---VATPIMRWL 628 A G + D+F T H V + GPV +A M ++ Sbjct: 1291 NATLGTELSVLDLFEAPTVGALAARVEAAGPGHGARPPLVPRDHTGPVPVSLAQQRMWFV 1350 Query: 629 REVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLD---RHATLRLRVEDTQEDTDEWSL 685 ++ + +N + + + DV + AL D RH TLR +T + + Sbjct: 1351 NQLAPGSAAYNIPIAVRLSGPL---DVAALRGALADVVERHQTLRTVFPNTSDGPVQQVR 1407 Query: 686 LVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSA-VWVRETSQ--LVLMIHH 742 V +A E + T L + A D + V A +W ++ L L+ HH Sbjct: 1408 SVADAALDLEPEDV-TETQLPQRLQGVATAPFDVSVQLPVRAHLWRLGPTEHVLALVAHH 1466 Query: 743 LAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAE-HAKTDTVRDLADA 801 +A DG+S L D+ +A+ G P +A ++ E D R LA Sbjct: 1467 VAADGLSMAPLARDVMVAYGARAAGTEPAWPPLAVQYADYAVWQRELLGAEDDPRSLAAR 1526 Query: 802 ----WR-AVTSVPQ--ALPPVQP-DTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQ 853 WR +T P LP +P + G +S ++ R+LL EV + A + Sbjct: 1527 QIAFWRDELTGAPDLLELPTDRPRPPQQSMRGGTVSCTIAPHLHRRLL-EVAGEYEASLF 1585 Query: 854 DILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 +L A + +D IG V G G + +L VG F Sbjct: 1586 MVLHAALAVLLARASGATDVTIGSPVSGRG-------EAELDDLVGMF 1626 Score = 399 bits (1024), Expect = e-108 Identities = 298/894 (33%), Positives = 428/894 (47%), Gaps = 61/894 (6%) Query: 42 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRS 101 T+ LF Q R P AVAL GD TY E + RLA L G P + VA + RS Sbjct: 1802 TLTDLFDAQARRTPHAVALTFGDEQLTYAEFASRARRLARELIARGVGPESRVALSMRRS 1861 Query: 102 GEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTT----ADLRSRLDQYDL 157 + ++ + +V + G AY+P+DP HP AR ++++ A P LTT A L++ +D ++ Sbjct: 1862 FDLLIGMYAVTEAGGAYVPLDPDHPAARTEYVLASAAPACVLTTRRDRAGLQTDIDVLEI 1921 Query: 158 AVIDMA---DPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALH 214 +D+A D I RP + + RPD +AY+ YTSG+TG PK VAV+H + ++ + Sbjct: 1922 DSLDLAGRGDGPI--RPEERVGALRPDHVAYVIYTSGSTGRPKGVAVSHRAIVNRLAWMQ 1979 Query: 215 ADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVS 274 V Q FDVSVWE + L +G L + P L L+ V+ Sbjct: 1980 DRYHLTGTDVVVQKTPATFDVSVWEFFWPLQNGASLAIALPEGHRDPAYLSQLIHDRGVT 2039 Query: 275 VLCQTPS--AAGMLSPEGLEST---TLIVAGEACPTELVDRWAP-----GRVMINAYGPT 324 V PS AA ++ + ++ T+ +GE P + +A G + N YGPT Sbjct: 2040 VAHFVPSMLAAFVVGADPVQCRSLRTVFCSGEGLPPSTAEAFAEFVGPAGAELHNLYGPT 2099 Query: 325 EATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYI 384 EA + + ++VLD L PAP GV GELY+AG +A GY+ Sbjct: 2100 EAAVDVTYRQYTAADTVSVPIGTPVWNTQVYVLDARLHPAPVGVPGELYLAGVQLARGYV 2159 Query: 385 GRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEY----LGRADEQVKIRGYRIEL 440 GRPDLTA RFVA PFG G R+YRTGDLVRW G L+Y LGR D QVK+RG RIEL Sbjct: 2160 GRPDLTAERFVANPFGAPGTRLYRTGDLVRWRKTGHLDYSLDYLGRTDFQVKLRGLRIEL 2219 Query: 441 GEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAQLRTALAESLPAYMV 496 GE++A L GV QAVV+ R D + LVGY+ +PA LR +LAESLPAYMV Sbjct: 2220 GEVEATLLSRPGVAQAVVVVRRDELVGEALVGYVIADPGVELEPAALRESLAESLPAYMV 2279 Query: 497 PTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVG 556 P+ ++VLD PL GKLDRRALPAPE+ S ++ AP P E+ILA ++ +++G R+G Sbjct: 2280 PSQILVLDEFPLGSTGKLDRRALPAPEFGSVEAEFVAPRGPVEEILALIFGELVGTTRIG 2339 Query: 557 VDDSFFDLGGDSILSMQVVARAR-AAGIQCRPRDIF----VEQTXXXXXXXXXXXXESHV 611 V DSFFDLGG+S+ + ++VAR A RD+F V E Sbjct: 2340 VYDSFFDLGGNSLTATRLVARVNDALDAHIGVRDVFDAPTVAALALRIESGGMRGPERAP 2399 Query: 612 VDEGVGPVVATPI------MRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDR 665 ++ P A P+ M ++ + D + +N + + + + + +LDR Sbjct: 2400 LEPAERP-AAVPVSLAQKRMWFINQFDTSSAAYNVVLPVRLDGDLDRGALRAAVADVLDR 2458 Query: 666 HATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNR-LDPAAGAM 724 H +LR R D + ++VP A E + + + E R D Sbjct: 2459 HESLRTRF--PMIDGEPVQVIVPTAAVAPDLEPESVAEQDVAERVAEFAGRGFDVTVAPP 2516 Query: 725 VSAVWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAW-------AQHCTGQSIELPA 774 V ++ +R +T LV+++HH+ DG S L D+ A+ A H T +++ Sbjct: 2517 VRSLLLRVGPQTHVLVIVVHHICADGFSLAPLARDVMSAYIARTEDRAPHWTPLAVQY-- 2574 Query: 775 GGTSFARW-SALLAEHAKTDTV--RDLADAWRAVTSVPQA--LPPVQPDTDTYVTAGQLS 829 +A W +L D+V R L R + +P+ LP +P G + Sbjct: 2575 --ADYALWQQKVLGGTDDPDSVLSRQLEYWARTLDGLPEVLDLPTDRPRPSERTLRGAVH 2632 Query: 830 ASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHG 883 + L V A V + A + D IG + G G Sbjct: 2633 GFRLGPDVHRRLTAVARTHNATVFMAVHAALAALLARLGDTDDVAIGTPIAGRG 2686 Score = 80.9 bits (198), Expect = 2e-12 Identities = 81/336 (24%), Positives = 130/336 (38%), Gaps = 18/336 (5%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 + PL+ VQ+ + F + ++ Q +T+ G LD L T + Sbjct: 22 EAFPLSAVQRSMWFAQQLTPAV--PIFIAQY-VTLQGDLDVDLLSRCAVTAAEEFQSPFL 78 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 ++ GEP Q + D + +DLR D P + S DL Sbjct: 79 HLIDVDGEPYQFIDPDTDTSIEQVDLR-DHPDPTAAAHAWMEHDYSVPIDLTRDRLIDMT 137 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFG---HRLPA---AAPYRNFV--- 1261 +++ ++ + HH+ +DG+S + I A Y HR P A R + Sbjct: 138 ILQVGDREYLWYTRIHHVALDGYSGMTVANRIAALYTAALEHRDPEPNRALDLRELLAID 197 Query: 1262 -NWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVP--GPRGIESYRVSAETTRALGELAR 1318 + W + + G E + +A P +ES + AL R Sbjct: 198 QKYRASGRFQADREYWADHIAGIEAGSTLAETDAPVSAVSRLESAPLPEAVITALDSTDR 257 Query: 1319 SQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKV 1378 + T VL AA+ L RMTG+ DV VS R A + G+L+N P+RA V Sbjct: 258 TLEATPAAVLIAAFACYLARMTGRTDVLVNMPVSARTT--APLQRSGGMLVNVAPLRATV 315 Query: 1379 SADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG 1414 + TV DL+ ++Q L H+ ++ DI +G Sbjct: 316 LPNDTVADLVGRIQLELMGALRHQRCSIEDIRRDAG 351 >tr|Q50E74|Q50E74_STRFL Tax_Id=67294 (dptA)SubName: Full=Peptide synthetase 1;[Streptomyces filamentosus] Length = 5830 Score = 1330 bits (3443), Expect = 0.0 Identities = 851/2227 (38%), Positives = 1189/2227 (53%), Gaps = 183/2227 (8%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R + S++LL +DE + W + A T PG T+ L + R PD A+V D Sbjct: 1468 RPISSYELLGDDERALLAQWNDTAHPTPPG----TVLDLLESRAARTPDRPAVVENDHVL 1523 Query: 68 TYRELDEASNRLA-HVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHP 126 TY +L +NRLA H++ HG P VA +PRS E ++++L+VLKTGAAY+P+D HP Sbjct: 1524 TYADLHTRANRLARHLITAHGVGPERLVAVALPRSAELLVALLAVLKTGAAYVPLDLTHP 1583 Query: 127 DARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPD----- 181 R ++ D +P LT A L + D+ + + +P + ++ GP D Sbjct: 1584 AERTAVVLDDCRPAVILTDAGAARELPRRDIPQLRLDEPEVHAAIAEQPGGPVTDRDRTC 1643 Query: 182 -------DLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFD 234 +AY+ YTSG+TG PK VAV H ++ V P G V + FD Sbjct: 1644 VTPVSGEHVAYVIYTSGSTGRPKGVAVEHRSLADFVRYSVTAYP-GAFDVTLLHSPVTFD 1702 Query: 235 VSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGL--- 291 ++V ++ L+ GG + V + P +L + + TPS +L+ E Sbjct: 1703 LTVTSLFPPLVVGGAIHVADLTEACPP----SLAAAGGPTFVKATPSHLPLLTHEATWAA 1758 Query: 292 ESTTLIVAGEACPTELVDRW---APGRVMINAYGPTEATIYAA-----MSEPLXXXXXXX 343 + L+V GE +D+W +P V+ N YGPTEAT+ +P+ Sbjct: 1759 SAKVLLVGGEQLLGRELDKWRAGSPEAVVFNDYGPTEATVNCVDFRIDPGQPIGAGPVAI 1818 Query: 344 XXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETG 403 +FVLD LR P GVVGEL+VAG G+A GY+G+P LTA RFVACPFG+ G Sbjct: 1819 GRPLRNTR--VFVLDGGLRAVPVGVVGELHVAGEGLARGYLGQPGLTAERFVACPFGDAG 1876 Query: 404 ERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIARED 463 ERMYRTGDLVRW +DG LE++GR D+QVK+RG+RIELGE++AA+A GVD++VV+ RED Sbjct: 1877 ERMYRTGDLVRWRADGMLEFVGRVDDQVKVRGFRIELGEVEAAVAACPGVDRSVVVVRED 1936 Query: 464 RPGDKRLVGYITGTADPAQLRTAL-----AESLPAYMVPTAVVVLDTIPLTVNGKLDRRA 518 RPGD+RLV Y+T D A+ L A LP YMVP+AVVVLD IPLT NGK+DR A Sbjct: 1937 RPGDRRLVAYVTAAGDEAEGLAPLIVETAAGRLPGYMVPSAVVVLDEIPLTPNGKVDRAA 1996 Query: 519 LPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARA 578 LPAP AA ++R +P E+ L ++A+VLGVERVGVDD FFDLGGDSILS+Q+VARA Sbjct: 1997 LPAPRVAPAA-EFRVTGSPREEALCALFAEVLGVERVGVDDGFFDLGGDSILSIQLVARA 2055 Query: 579 RAAGIQCRPRDIFVEQTXXXXXXXXXXXX--ESHVVDEGVGPVVATPIMRWLRE-----V 631 R AG++ RD+F +T + VVD GVG V P++ WL E + Sbjct: 2056 RRAGLEVSVRDVFEHRTVRALAGVVRESGGVAAAVVDSGVGAVERWPVVEWLAERGGGGL 2115 Query: 632 DGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAG 691 G FNQ+V+ PAG+T D++ +L A+ +RH RLRV D+ + WSL V Sbjct: 2116 GGAVRAFNQSVVVATPAGITWDELRTVLDAVRERHDAWRLRVVDSGDGA--WSLRVDAPA 2173 Query: 692 AVGARECLRTVDALTDDV----------LVEARNRLDPAAGAMVSAVWVRETSQ----LV 737 G + + + D+ VEAR+RLDP G MV AVW+ LV Sbjct: 2174 PGGEPDWITRHGMASADLEEQVNAVRAAAVEARSRLDPLTGRMVRAVWLDRGPDRRGVLV 2233 Query: 738 LMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRD 797 L+ HHL VDGVSWRI+L DL AW Q G + L GTS W+A LAE + Sbjct: 2234 LVAHHLVVDGVSWRIVLGDLGEAWTQARAGGHVRLDTVGTSLRGWAAALAEQGRHGARAT 2293 Query: 798 LADAWRAVT--SVPQALP-PVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQD 854 A+ W + S P P V P D + + + V +R LL EVP+ GVQ+ Sbjct: 2294 EANLWAQMVHGSDPLVGPRAVDPSVDVFGVVESVGSRASVGVSRALLTEVPSVLGVGVQE 2353 Query: 855 ILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENL 914 +LL AFGLA T + R + + VDVEGHGR ++ DLSRTVGWFT+ YPV L +E Sbjct: 2354 VLLAAFGLAVTRWRGRGGSVV-VDVEGHGRNEDAVPGADLSRTVGWFTSIYPVRLPLEPA 2412 Query: 915 PWEQVVAGDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEVDLGGSD---PTIGFNYL 970 W+++ AG A+G V+ +KE LR+LP+ GL YG+LRYL+PE + P GFNYL Sbjct: 2413 AWDEIRAGGPAVGRTVREIKECLRTLPDQGLGYGILRYLDPENGPALAQHPTPHFGFNYL 2472 Query: 971 GRL------------------------GAGAGELSEELWR--IDQXXXXXXXXXXXVPMP 1004 GR+ G A + EE W + +P Sbjct: 2473 GRVSVSADAASLDEGDAHADGLGGLVGGRAAADSDEEQWADWVPVSGPFAVGAGQDPVLP 2532 Query: 1005 LMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRG-GGG 1063 + H VE NA T+DT +GP L +W+W + E + L+R W EAL G+ AH R G Sbjct: 2533 VAHAVEFNAITLDTPDGPRLSVTWSWPTTLLSESRIRELARFWDEALEGLVAHARRPDAG 2592 Query: 1064 GLTPSDVAPARLTQRQIDELSQRYDVT----DVLPLTPVQQGLLFHSTFARGIGDDVYAV 1119 GLTPSD+ L +++ L DVT D+LP++P+Q+GLLFHS+FA G DVY Sbjct: 2593 GLTPSDLPLVALDHAELEALQA--DVTGGVHDILPVSPLQEGLLFHSSFAAD-GVDVYVG 2649 Query: 1120 QLDITITGVLDQHRLRDAVHTVVARHPNLAARFVE-QFGEPVQVLTADPMIAWRYLDLRG 1178 QL +TG +D L V ++V RH L + + Q GE + V+ W+Y+ Sbjct: 2650 QLTFDLTGPVDADHLHAVVESLVTRHDVLRTGYRQAQSGEWIAVVARQVHTPWQYIH--- 2706 Query: 1179 DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPIL 1238 T D + + L ER D+ + P R L R + RF++T+HH+++DGWS+ +L Sbjct: 2707 ---TLDTDADTLTNDERWRPFDMTQGPLARFTLARINDTHFRFIVTYHHVILDGWSVAVL 2763 Query: 1239 LQEIFAGY----FGHR--LPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPP 1292 ++E+F Y G R +P + P R+F+ WL WR L G PT++A Sbjct: 2764 IRELFTTYRDTALGRRPEVPYSPPRRDFMAWLAERDQTAAGQAWRSALAGLAEPTVLAL- 2822 Query: 1293 GVPG----PRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFG 1348 G G P +E +S E T L AR + T+ +V+QAAW +L R+ G+ DV FG Sbjct: 2823 GTEGSGVIPEVLEE-EISEELTSELVAWARGRGVTVASVVQAAWALVLGRLVGRDDVVFG 2881 Query: 1349 TAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALND 1408 VSGRPA++AG E MVGL +NT+P+RA++ ++G + +LQ + LEH+H+ L + Sbjct: 2882 LTVSGRPAEVAGVEDMVGLFVNTIPLRARMDPAESLGAFVERLQREQTELLEHQHVRLAE 2941 Query: 1409 IHHVSGHEQLFDTLFLYESYPIDT----SAFMGVQELAVTEFNNREYNHYPLSVMALPGH 1464 + +GH++LFD ++E+YP+D+ S F G L + + H+ L++ +P Sbjct: 2942 VQRWAGHKELFDVGMVFENYPMDSLLQDSLFHG-SGLQIDGIQGADATHFALNLAVVPLP 3000 Query: 1465 ELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWAN- 1523 + R+ Y VFD + L R LE ++ + +S +DV+ ER L W Sbjct: 3001 AMRFRLGYRPDVFDAGRVRELWGWIVRALECVVCERDVPVSGVDVLGAGERETLLGWGAG 3060 Query: 1524 -----RAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLA 1578 RA+ + + +F +V DP+A AV G +Y EL+ AN +A L Sbjct: 3061 AEPGVRALPGAGAGAGAGLVGLFEERVRTDPDAVAVRGAGVEWSYAELNARANAVARWLI 3120 Query: 1579 VYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVT 1638 G P + V +++ R D + +LAV K+G YLP+DP P R++++L DA AV Sbjct: 3121 GRGVGPERGVGVVMDRGPDVVAMLLAVAKSGGFYLPVDPQWPTERIDWVLADAGIDLAVV 3180 Query: 1639 TGDLRSRFDGF-DLQVVEVDDPAVEIYPSTTLLTPSPDDI-------------AYMIYTS 1684 +L + + D +VV+ A E + T + D Y+IYTS Sbjct: 3181 GENLAAAVEAVRDCEVVDYAQIARETRLNEQAATDAGDVTDGERVSALLSGHPLYVIYTS 3240 Query: 1685 GTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRL 1744 G+TG+PKGV +TH +V L + SL FD++V ++ L+ GG + Sbjct: 3241 GSTGLPKGVVVTHASVGAYLRRGRNAYRGAADGLGHVHSSLAFDLTVTVLFTPLVSGGCV 3300 Query: 1745 VIVPESIAGSPDDLHALLVSEGVNVLYQTPSAV-------RMMSPEGLEGTALVVAGEAC 1797 + G DD L G L TPS + R+++P+ L++ GEA Sbjct: 3301 TL------GDLDDTANGL---GATFLKATPSHLPLLGQLDRVLAPDA----TLLLGGEAL 3347 Query: 1798 PTEVVDRWAVDR---VMINAYGPTESTIYAAISAPLSPGSDV----VPIGSPVPKGATFV 1850 + W +INAYGPTE T+ A + PG + VPIG P FV Sbjct: 3348 TAGALHHWRTHHPHTTVINAYGPTELTVNCA-EYRIPPGHCLPDGPVPIGRPFTGHHLFV 3406 Query: 1851 LDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWG 1910 LD LR PP +GELY+A LT RFVACPF PG RMYRTGDL RW Sbjct: 3407 LDPALRLTPPDTIGELYVAGDGLARGYLGRPDLTAERFVACPFRSPGERMYRTGDLARWR 3466 Query: 1911 DDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITG 1970 DG L+++GRAD+QVKIRG+RIELGE++AA++ V +A+ + REDRPGD+RLV Y+TG Sbjct: 3467 SDGTLEFIGRADDQVKIRGFRIELGEVEAAVAAHPHVARAIAVVREDRPGDQRLVAYVTG 3526 Query: 1971 TADPAAARSELTN----RLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRA 2026 +DP+ S +T+ RLPAYMVP+AVV L+ +PLT NGK+DR ALPAP S RA Sbjct: 3527 -SDPSGLSSAVTDTVAGRLPAYMVPSAVVVLDQIPLTPNGKVDRAALPAPGTASGTTSRA 3585 Query: 2027 PETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFE 2086 P T E+ L +FA VLG+++ A R+T+ + +AL DL VR LF+ Sbjct: 3586 PGTAREEILCTLFADVLGLDQVGVDEDFFDLGGHSLLATRLTSRIRSALGIDLGVRALFK 3645 Query: 2087 APTVAKL 2093 APTV +L Sbjct: 3646 APTVGRL 3652 Score = 489 bits (1259), Expect = e-135 Identities = 358/1041 (34%), Positives = 496/1041 (47%), Gaps = 76/1041 (7%) Query: 1117 YAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPV--QVLTADPMIAWRYL 1174 Y + + + +TG LD L A+ V+ARH +L + V +L D L Sbjct: 3698 YNIPMALRLTGRLDLTALEAALTDVIARHESLRTVIAQDDSGGVWQNILPTDDTRTHLTL 3757 Query: 1175 DLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWS 1234 D D H ++ DL RA + R + ++H +L HHI DGWS Sbjct: 3758 DTMPVDA---HTLQNRVDEAARHPFDLTTEIPLRATVFRVTDDEHVLLLVLHHIAGDGWS 3814 Query: 1235 LPILLQEIFAGY------FGHRLPA-AAPYRNFVNWLXXXXXXXXXXX---------WRE 1278 + L ++ A Y +LPA A Y ++ W W Sbjct: 3815 MAPLAHDLSAAYTVRLEHHAPQLPALAVQYADYAAWQRDVLGTENNTSSQLSTQLDYWYS 3874 Query: 1279 VLDGFET----PTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHTTINTVLQAAWT 1333 L+G PT P V + V + + L LAR+Q T+ V+QAA Sbjct: 3875 KLEGLPAELTLPTSRVRPAVASHACDRVEFTVPHDVHQGLTALARTQGATVFMVVQAALA 3934 Query: 1334 QLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQS 1393 LL R+ D+ GT ++GR E+++GL +NT+ +R VS D T +LL ++++ Sbjct: 3935 ALLSRLGAGTDIPIGTPIAGRTDQ--AMENLIGLFVNTLVLRTDVSGDPTFAELLARVRT 3992 Query: 1394 HHNDTLEHEHL-------ALNDIHHVSGHEQLFDTLFLYESYPIDTS-----AFMGVQEL 1441 D H+ + A+N ++ H LF + + + ++ A G+ Sbjct: 3993 TALDAYAHQDIPFERLVEAINPERSLTRHP-LFQVMLAFNNTDRRSALDALDAMPGLHAR 4051 Query: 1442 AVTEFNNREYNHYPLSVMALPGH-ELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP 1500 S + PG E+ ++Y T +FD S E + +R RLL + P Sbjct: 4052 PADVLAVTSPYDLAFSFVETPGSTEMPGILDYATDLFDRSTAEAMTERLVRLLAEIARRP 4111 Query: 1501 ARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES 1560 + + ++ DE L A A + +PE+F QV A AV EGE Sbjct: 4112 ELSVGDIGILSADEVKALSPEAPPAAEELHTST---LPELFEEQVAARGHAVAVVCEGEE 4168 Query: 1561 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP 1620 L+Y EL+ AN+LA +L GA P + V + +PR D IVA+LAV KTGAAY+P+DP P Sbjct: 4169 LSYKELNARANRLARVLMERGAGPERFVGVALPRGLDLIVALLAVTKTGAAYVPLDPEYP 4228 Query: 1621 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIY----PSTTLLTPS-PD 1675 RL +M+ DA P A VT+ D+ +E+DD A+ P T S P Sbjct: 4229 TDRLAYMVTDANPTAVVTSTDVHIPLIA---PRIELDDEAIRTELAAAPDTAPCVGSGPA 4285 Query: 1676 DIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIW 1735 AY+IYTSG+TG PKGV I+H NV ++ GP VW+ +HS FD SVWEIW Sbjct: 4286 HPAYVIYTSGSTGRPKGVVISHANVVRLFTACSDSFDFGPDHVWTLFHSYAFDFSVWEIW 4345 Query: 1736 GALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS------PEGLEGTA 1789 GALLHGGRLV+VP + SP + ALL + V +L QTPSA ++ P G A Sbjct: 4346 GALLHGGRLVVVPFEVTRSPAEFLALLAEQQVTLLSQTPSAFHQLTEAARQEPARCAGLA 4405 Query: 1790 L---VVAGEACPTEVVDRW-----AVDRVMINAYGPTESTIYAAISAPLSPGSDVV---P 1838 L V GEA + W ++N YG TE+T++ + PL + + P Sbjct: 4406 LRHVVFGGEALDPSRLRDWFDLPLGSRPTLVNMYGITETTVHVTV-LPLEDRATSLSGSP 4464 Query: 1839 IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGA 1898 IG P+ +VLDE LRPVPPG VGE+Y+A LT RFVA P G Sbjct: 4465 IGRPLADLQVYVLDERLRPVPPGTVGEMYVAGAGLARGYLGRPALTAERFVADPNSRSGG 4524 Query: 1899 RMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDR 1958 R+YRTGDL + DG L+Y+GR D QVKIRG+RIELGEI+AAL GV QAVV+ R+++ Sbjct: 4525 RLYRTGDLAKVRPDGGLEYVGRGDRQVKIRGFRIELGEIEAALVTHAGVVQAVVLVRDEQ 4584 Query: 1959 PGDKRLVGYITGTADP-----AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRAL 2013 D+RLV ++ A L LPAYMVP+A TL+ LPLT NGKLDR AL Sbjct: 4585 TDDQRLVAHVVPALPHRAPTLAELHEHLAATLPAYMVPSAYRTLDELPLTANGKLDRAAL 4644 Query: 2014 PAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNT 2073 + R P T E+ L +FA VL + A R+ +AV Sbjct: 4645 AGQWQGGTRTRRLPRTPQEEILCELFADVLRLPAAGADDDFFALGGHSLLATRLLSAVRG 4704 Query: 2074 ALDADLSVRTLFEAPTVAKLS 2094 L +L +R LF APT A L+ Sbjct: 4705 TLGVELGIRDLFAAPTPAGLA 4725 Score = 470 bits (1210), Expect = e-129 Identities = 359/1070 (33%), Positives = 520/1070 (48%), Gaps = 84/1070 (7%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+ QQ L F Y + + + G LD L A+ V RH L Sbjct: 1040 LPLSHAQQRLWFLDQVEGP--SPAYNIPTAVRLEGPLDIPALAVALQDVTNRHEPLRTLL 1097 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALI 1212 E P QV+ P A R +L + P L A R DL +A L Sbjct: 1098 AEDSEGPHQVIL--PPEAARP-ELTHSTVAPGDLAAALAEAARRPF-DLAGEIPLKAHLF 1153 Query: 1213 RTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNFV---- 1261 + H +L HH DG S+ +L++++ Y R P Y + Sbjct: 1154 GCGPDDHTLLLLVHHTAGDGASVEVLVRDLAHAYGARRAGDAPHFEPLPLQYADHTLRRR 1213 Query: 1262 NWLXXXXXXXXXXXWREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTRALGEL 1316 + L WR+ L G E PT P VP RG ++ V T L + Sbjct: 1214 HLLDDPSDSTQLDHWRDALAGLPEQLELPTDHTRPAVPTRRGEAIAFTVPEHTHHTLRAM 1273 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA 1376 A++ T+ V+QAA LL R D+ GT V+GR D G E +VG +NT+ +R Sbjct: 1274 AQAHGVTVFMVMQAALAALLSRHGAGHDIPLGTPVAGRSDD--GTEDLVGFFVNTLVLRN 1331 Query: 1377 KVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQ------LFDTLFLYE---- 1426 VS D T +L+ ++++ + D ++ + + V E+ LF + Y Sbjct: 1332 DVSGDPTFAELVSRVRAANLDAYAYQDVPFERLVDVLKPERSLSWHPLFQIMIAYNGPAT 1391 Query: 1427 SYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRV----EYDTSVFDVSEI 1482 + D S F G+ + + LS L H GL + E+ T +F Sbjct: 1392 NDTADGSRFAGLTSRVHAVHTGM--SKFDLSFF-LTEHADGLGIDGALEFSTDLFTRITA 1448 Query: 1483 ETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFA 1542 E L+ R+ +LE P R +SS +++ DDER L +W + A T P ++ ++ Sbjct: 1449 ERLVQRYLTVLEQAAGAPDRPISSYELLGDDERALLAQWNDTAHPTPP----GTVLDLLE 1504 Query: 1543 RQVERDPEAPAVTFEGESLNYGELDEAANQLA-NLLAVYGAAPGKSVALMVPRSADAIVA 1601 + R P+ PAV L Y +L AN+LA +L+ +G P + VA+ +PRSA+ +VA Sbjct: 1505 SRAARTPDRPAVVENDHVLTYADLHTRANRLARHLITAHGVGPERLVAVALPRSAELLVA 1564 Query: 1602 ILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAV 1661 +LAVLKTGAAY+P+D + PA R +L D +P +T D+ + +D+P V Sbjct: 1565 LLAVLKTGAAYVPLDLTHPAERTAVVLDDCRPAVILTDAGAARELPRRDIPQLRLDEPEV 1624 Query: 1662 EIY-------PST----TLLTP-SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPA 1709 P T T +TP S + +AY+IYTSG+TG PKGVA+ H ++ D + Sbjct: 1625 HAAIAEQPGGPVTDRDRTCVTPVSGEHVAYVIYTSGSTGRPKGVAVEHRSLA---DFVRY 1681 Query: 1710 ELPAGPGAV-WSQWHSLV-FDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 + A PGA + HS V FD++V ++ L+ GG + + + A P +L + G Sbjct: 1682 SVTAYPGAFDVTLLHSPVTFDLTVTSLFPPLVVGGAIHVADLTEACPP----SLAAAGGP 1737 Query: 1768 NVLYQTPSAVRMMSPEGL---EGTALVVAGEACPTEVVDRWAV---DRVMINAYGPTEST 1821 + TPS + +++ E L+V GE +D+W + V+ N YGPTE+T Sbjct: 1738 TFVKATPSHLPLLTHEATWAASAKVLLVGGEQLLGRELDKWRAGSPEAVVFNDYGPTEAT 1797 Query: 1822 IYAAISAPLSPGSDV----VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXX 1877 + + + PG + V IG P+ FVLD LR VP GVVGEL++A Sbjct: 1798 VNC-VDFRIDPGQPIGAGPVAIGRPLRNTRVFVLDGGLRAVPVGVVGELHVAGEGLARGY 1856 Query: 1878 XXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEI 1937 LT RFVACPFG+ G RMYRTGDLVRW DG L+++GR D+QVK+RG+RIELGE+ Sbjct: 1857 LGQPGLTAERFVACPFGDAGERMYRTGDLVRWRADGMLEFVGRVDDQVKVRGFRIELGEV 1916 Query: 1938 QAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSEL-----TNRLPAYMVPA 1992 +AA++ GVD++VV+ REDRPGD+RLV Y+T D A + L RLP YMVP+ Sbjct: 1917 EAAVAACPGVDRSVVVVREDRPGDRRLVAYVTAAGDEAEGLAPLIVETAAGRLPGYMVPS 1976 Query: 1993 AVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXX 2052 AVV L+ +PLT NGK+DR ALPAP A +R + E+ L +FA VLGVER Sbjct: 1977 AVVVLDEIPLTPNGKVDRAALPAPRVAPAAEFRVTGSPREEALCALFAEVLGVERVGVDD 2036 Query: 2053 XXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 ++++ A A ++SVR +FE TV L+ V G Sbjct: 2037 GFFDLGGDSILSIQLVARARRA-GLEVSVRDVFEHRTVRALAGVVRESGG 2085 Score = 449 bits (1154), Expect = e-123 Identities = 331/939 (35%), Positives = 467/939 (49%), Gaps = 70/939 (7%) Query: 42 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRS 101 T+P LF EQV AVA+V +Y+EL+ +NRLA VL E GA P V +PR Sbjct: 4144 TLPELFEEQVAARGHAVAVVCEGEELSYKELNARANRLARVLMERGAGPERFVGVALPRG 4203 Query: 102 GEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLR-----SRLDQYD 156 + I+++L+V KTGAAY+P+DP +P R+ +M++DA P A +T+ D+ R++ D Sbjct: 4204 LDLIVALLAVTKTGAAYVPLDPEYPTDRLAYMVTDANPTAVVTSTDVHIPLIAPRIELDD 4263 Query: 157 LAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHAD 216 A+ A D P G P AY+ YTSG+TG PK V ++H NV +L +A Sbjct: 4264 EAIRTELAAAPDTAPC---VGSGPAHPAYVIYTSGSTGRPKGVVISHANVVRLFTACSDS 4320 Query: 217 LPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVL 276 GP VW+ +HS FD SVWEIWGALLHGGRLVVVP V SP + LL ++V++L Sbjct: 4321 FDFGPDHVWTLFHSYAFDFSVWEIWGALLHGGRLVVVPFEVTRSPAEFLALLAEQQVTLL 4380 Query: 277 CQTPSAAGMLSPE---------GLESTTLIVAGEACPTELVDRW-----APGRVMINAYG 322 QTPSA L+ GL ++ GEA + W ++N YG Sbjct: 4381 SQTPSAFHQLTEAARQEPARCAGLALRHVVFGGEALDPSRLRDWFDLPLGSRPTLVNMYG 4440 Query: 323 PTEATIYAAMS--EPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVA 380 TE T++ + E ++VLD+ LRP P G VGE+YVAG G+A Sbjct: 4441 ITETTVHVTVLPLEDRATSLSGSPIGRPLADLQVYVLDERLRPVPPGTVGEMYVAGAGLA 4500 Query: 381 TGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIEL 440 GY+GRP LTA RFVA P +G R+YRTGDL + DG LEY+GR D QVKIRG+RIEL Sbjct: 4501 RGYLGRPALTAERFVADPNSRSGGRLYRTGDLAKVRPDGGLEYVGRGDRQVKIRGFRIEL 4560 Query: 441 GEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP-----AQLRTALAESLPAYM 495 GEI+AAL GV QAVV+ R+++ D+RLV ++ A+L LA +LPAYM Sbjct: 4561 GEIEAALVTHAGVVQAVVLVRDEQTDDQRLVAHVVPALPHRAPTLAELHEHLAATLPAYM 4620 Query: 496 VPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERV 555 VP+A LD +PLT NGKLDR AL A +++ R P TP E+IL +++A VL + Sbjct: 4621 VPSAYRTLDELPLTANGKLDRAAL-AGQWQGGTRTRRLPRTPQEEILCELFADVLRLPAA 4679 Query: 556 GVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXXXXXXXXXXES----H 610 G DD FF LGG S+L+ ++++ R G++ RD+F T + Sbjct: 4680 GADDDFFALGGHSLLATRLLSAVRGTLGVELGIRDLFAAPTPAGLATVLAASGTALPPVT 4739 Query: 611 VVD---EGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHA 667 +D E + A + +L +++GP+ +N V + + + L + RH Sbjct: 4740 RIDRRPERLPLSFAQRRLWFLSKLEGPSATYNIPVAVRLTGALDVPALRAALGDVTARHE 4799 Query: 668 TLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSA 727 +LR D + + L++P A + TV + + D + + A Sbjct: 4800 SLRTVFPD--DGGEPRQLVLPHAEPPFLTHEV-TVGEVAEQAASATGYAFDITSDTPLRA 4856 Query: 728 VWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFAR 781 +R E LV++IHH+A DG S L+ DL A+ G + E LP +A Sbjct: 4857 TLLRVSPEEHVLVVVIHHIAGDGWSMGPLVRDLVTAYRARTRGDAPEYTPLPVQYADYAL 4916 Query: 782 WSALLA--EHAKTDTVRDLADAWR-AVTSVPQ--ALPPVQP-DTDTYVTAGQLSASLDVE 835 W +A E A WR + +P+ LP +P + G++ L Sbjct: 4917 WQHAVAGDEDAPDGRTARRLGYWREMLAGLPEEHTLPADRPRPVRSSHRGGRVRFELPAG 4976 Query: 836 TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLS 895 R LL V RA + ++ A + D PIG V G G DE DV Sbjct: 4977 VHRSLLA-VARDRRATLFMVVQAALAGLLSRLGAGDDIPIGTPVAGRG--DEALDDV--- 5030 Query: 896 RTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVK 934 VG+F V L +AGD + +V V+ Sbjct: 5031 --VGFF---------VNTLVLRTNLAGDPSFADLVDRVR 5058 Score = 442 bits (1138), Expect = e-121 Identities = 332/1012 (32%), Positives = 481/1012 (47%), Gaps = 81/1012 (8%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+ Q+ L F S Y + + + +TG LD LR A+ V ARH +L F Sbjct: 4748 LPLSFAQRRLWFLSKLEGPSA--TYNIPVAVRLTGALDVPALRAALGDVTARHESLRTVF 4805 Query: 1153 VEQFGEPVQVLT--ADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 + GEP Q++ A+P + + E+ + A+ D+ RA Sbjct: 4806 PDDGGEPRQLVLPHAEPPFLTHEVTVG--------EVAEQAASATGYAFDITSDTPLRAT 4857 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHR-------LPAAAPYRNFVNW 1263 L+R S +H V+ HHI DGWS+ L++++ Y P Y ++ W Sbjct: 4858 LLRVSPEEHVLVVVIHHIAGDGWSMGPLVRDLVTAYRARTRGDAPEYTPLPVQYADYALW 4917 Query: 1264 ---------LXXXXXXXXXXXWREVLDGF-ETPTLVAPPGVPGPRGIES--------YRV 1305 WRE+L G E TL A PR + S + + Sbjct: 4918 QHAVAGDEDAPDGRTARRLGYWREMLAGLPEEHTLPADR----PRPVRSSHRGGRVRFEL 4973 Query: 1306 SAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMV 1365 A R+L +AR + T+ V+QAA LL R+ D+ GT V+GR + + +V Sbjct: 4974 PAGVHRSLLAVARDRRATLFMVVQAALAGLLSRLGAGDDIPIGTPVAGRGDE--ALDDVV 5031 Query: 1366 GLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLY 1425 G +NT+ +R ++ D + DL+ ++++ D H+ + + + L+ Sbjct: 5032 GFFVNTLVLRTNLAGDPSFADLVDRVRTADLDAFAHQDVPFERLVEALAPRRSLARHPLF 5091 Query: 1426 ESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALP--------------GHELGLRV- 1470 + + T+A + A+ + YPL A G GL V Sbjct: 5092 QIWYTLTNADQDITGQALNALPGLTGDEYPLGASAAKFDLSFTFTEHRTPDGDAAGLSVL 5151 Query: 1471 -EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQ-LDEWANRAVLT 1528 +Y + ++D L R A+ DP L ++ ++ DDER + L +W + Sbjct: 5152 LDYSSDLYDHGTAAALGHRLTGFFAALAADPTAPLGTVPLLTDDERDRILGDWGSGTHTP 5211 Query: 1529 QPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSV 1588 P P+S+ E R+ DP+A AV E L+Y EL+ + + A LLA G V Sbjct: 5212 LP---PRSVAEQIVRRAALDPDAVAVITAEEELSYRELERLSGETARLLADRGIGRESLV 5268 Query: 1589 ALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDG 1648 A+ +PR+A + +L VL+TGAAYLP+D PA RL +L DA+P +T L R Sbjct: 5269 AVALPRTAGLVTTLLGVLRTGAAYLPLDTGYPAERLAHVLSDARPDLVLTHAGLAGRLPA 5328 Query: 1649 FDLQVVEVDDPAVEIYPSTTLLT-PSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 V VD+P + + T PS D +AY+I+TSG+TG PKGVAI ++ L Sbjct: 5329 GLAPTVLVDEPQPPAAAAPAVPTSPSGDHLAYVIHTSGSTGRPKGVAIAESSLRAFLADA 5388 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 P ++ FD++ E++ LL G +V+ E P + +L V Sbjct: 5389 VRRHDLTPHDRLLAVTTVGFDIAGLELFAPLLAGAAIVLADEDAVRDPASITSLCARHHV 5448 Query: 1768 NVLYQTPSAVRMM-------SPEGLEGTALVVAGEACPTEVVD-RWAVDRVMINAYGPTE 1819 V+ TPS R M + LE ++V GE P ++ A + N YGPTE Sbjct: 5449 TVVQATPSWWRAMLDGAPADAAARLEHVRILVGGEPLPADLARVLTATGAAVTNVYGPTE 5508 Query: 1820 STIYAAISAPLSPGSDVVP-IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXX 1878 +TI+A +APL+ G D P IG+P+ +LD L PVPPGV GE+++A Sbjct: 5509 ATIWAT-AAPLTAGDDRTPGIGTPLDNWRVHILDAALGPVPPGVPGEIHIAGSGLARGYL 5567 Query: 1879 XXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQ 1938 LT RFVA PF PG RMYRTGDL R+ DG L++LGR D+QVK+RG+RIELG+++ Sbjct: 5568 RRPDLTAERFVANPFA-PGERMYRTGDLGRFRPDGTLEHLGRVDDQVKVRGFRIELGDVE 5626 Query: 1939 AALSDVDGVDQAVVIAREDRPGDKRLVGYIT---GTADPAAA--RSELTNRLPAYMVPAA 1993 AAL+ V +A R D G RLV Y+ GT P A R + LP YMVP+A Sbjct: 5627 AALARHPDVGRAAAAVRPDHRGQGRLVAYVVPRPGTRGPDAGELRETVRELLPDYMVPSA 5686 Query: 1994 VVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGV 2045 VTL TLP T NGKLDR ALPAP + RAP T EK LAG+FA +LG+ Sbjct: 5687 QVTLTTLPHTPNGKLDRAALPAPVF-GTPAGRAPATREEKILAGLFADILGL 5737 Score = 436 bits (1121), Expect = e-119 Identities = 329/935 (35%), Positives = 443/935 (47%), Gaps = 54/935 (5%) Query: 28 GNRAVLTDPG-----PTP-VTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAH 81 G RA L D P P T+P LFAEQ R PDA A+ TYR+L + R A Sbjct: 439 GTRARLLDDSRGTERPVPRATLPELFAEQARRTPDAPAVQHDGTVLTYRDLHRSVERAAG 498 Query: 82 VLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVA 141 LA G + VA +P+S E++ +L + + GAAY+P+DP HP R+ ++ D +P Sbjct: 499 RLAGLGLRTEDVVALALPKSAESVAILLGIQRAGAAYVPLDPTHPAERLARVLDDTRPRY 558 Query: 142 ALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAV 201 +TT + + + AD + P A P P + AY+ TSG+TG PK V V Sbjct: 559 LVTTGHIDGL--SHPTPQLAAADLLREGGPEPAPGRPAPGNAAYIIQTSGSTGRPKGVVV 616 Query: 202 THHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSP 261 TH + L + +GP Q+ S FDV V E+ LL GG LV+ P+ G + Sbjct: 617 THEGLATLAADQIRRYRTGPDARVLQFISPGFDVFVSELSMTLLSGGCLVIPPD--GLTG 674 Query: 262 DDLHNLLITEKVSVLCQTPSAAGMLSPEGLEST-TLIVAGEACPTELVDRWAPGRVMINA 320 L + L E V+ TP A + L TLIV GE CP E+ D+W GR ++NA Sbjct: 675 RHLADFLAAEAVTTTSLTPGALATMPATDLPHLRTLIVGGEVCPPEIFDQWGRGRDIVNA 734 Query: 321 YGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVA 380 YGPTE T+ A +VLD L P P+G GELY+AG G+A Sbjct: 735 YGPTETTVEATAWHRDGATHGPVPLGRPTLNRRGYVLDPALEPVPDGTTGELYLAGEGLA 794 Query: 381 TGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIEL 440 GY+ P TA RFVA PFG G RMYRTGDLVR S G LE++GRAD QVK+RG+RIEL Sbjct: 795 RGYVAAPGPTAERFVADPFGPPGSRMYRTGDLVRRRSGGMLEFVGRADGQVKLRGFRIEL 854 Query: 441 GEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMV 496 GE+QAAL L GV QA V+ REDRPGD RLVGYI D +LR ALA +LP +MV Sbjct: 855 GEVQAALTALPGVRQAGVLIREDRPGDPRLVGYIVPAPGAEPDAGELRAALARTLPPHMV 914 Query: 497 PTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVG 556 P A+V L +PLT NGKLDR ALP P R+ + R P TP E+ L ++A VLGV V Sbjct: 915 PWALVPLPALPLTSNGKLDRAALPVPAARAGGSGQR-PVTPQEKTLCALFADVLGVTEVA 973 Query: 557 VDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXXXXXXXXXXESHVV--- 612 DD FF+LGG S+ +++AR R G RD+F T H Sbjct: 974 TDDVFFELGGHSLNGTRLLARIRTEFGTDLTLRDLFAFPTVAGLLPLLDDNGRQHTTPPL 1033 Query: 613 ---DEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATL 669 E + A + +L +V+GP+ +N + + + V LQ + +RH L Sbjct: 1034 PPRPERLPLSHAQQRLWFLDQVEGPSPAYNIPTAVRLEGPLDIPALAVALQDVTNRHEPL 1093 Query: 670 RLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDV---LVEARNRLDPAAGAMVS 726 R + + E + +L PEA AR L D+ L EA R AG + Sbjct: 1094 RTLLAEDSEGPHQ-VILPPEA----ARPELTHSTVAPGDLAAALAEAARRPFDLAGEIPL 1148 Query: 727 AVWV----RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARW 782 + + L+L++HH A DG S +L+ DL A+ G + +A Sbjct: 1149 KAHLFGCGPDDHTLLLLVHHTAGDGASVEVLVRDLAHAYGARRAGDAPHFEPLPLQYADH 1208 Query: 783 SALLAEHAKTDTVRDLADAWR-AVTSVPQALPPVQPDTDTYVTA--GQLSASLDVETTRQ 839 + + D WR A+ +P+ L T V G+ A E T Sbjct: 1209 TLRRRHLLDDPSDSTQLDHWRDALAGLPEQLELPTDHTRPAVPTRRGEAIAFTVPEHTHH 1268 Query: 840 LLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVG 899 L + A V ++ A + D P+G V GR D+ D+ VG Sbjct: 1269 TLRAMAQAHGVTVFMVMQAALAALLSRHGAGHDIPLGTPVA--GRSDDGTEDL-----VG 1321 Query: 900 WFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVK 934 +F V L V+GD +V V+ Sbjct: 1322 FF---------VNTLVLRNDVSGDPTFAELVSRVR 1347 Score = 435 bits (1118), Expect = e-119 Identities = 347/1038 (33%), Positives = 481/1038 (46%), Gaps = 65/1038 (6%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDD--VYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 L +T QQ + A + DD +Y +++TG +D L AV + L Sbjct: 8 LGVTAAQQSVWL----AGQLADDHRLYHCAAYLSLTGSIDPRTLGTAVRRTLDETEALRT 63 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 RFV Q GE +Q+L D GD P+ A +A L T A Sbjct: 64 RFVPQDGELLQILEPGAGQLLLEADFSGDP-DPERAAHDWMHAALAAPVRLDRAGTATHA 122 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQE---IFAGYFGHRLPAAAPYRNFVNWLXXX 1267 L+ ++H +HHI +DG+ + L+ ++ P P+ L Sbjct: 123 LLTLGPSRHLLYFGYHHIALDGYGALLHLRRLAHVYTALSNGDDPGPCPFGPLAGVLTEE 182 Query: 1268 XXXXXXXXWREVLDG-FETPTLVAPPGVPGPRGIES----------YRVSAETTRALGEL 1316 R DG F T +L PG E+ +S E T L Sbjct: 183 AAYRDSDNHRR--DGEFWTRSLAGADEAPGLSEREAGALAVPLRRTVELSGERTEKLAAS 240 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAG-AESMVGLLINTVPIR 1375 A + +++L AA + R D G V+ R L G A +L N VP+R Sbjct: 241 AAATGARWSSLLVAATAAFVRRHAAADDTVIGLPVTAR---LTGPALRTPCMLANDVPLR 297 Query: 1376 ---------AKVSADTT--VGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFL 1424 A + ADTT VG L R H E H L + +G ++ + Sbjct: 298 LDARLDAPFAALLADTTRAVGTLAR----HQRFRGEELHRNLGGVGRTAGLARVTVNVLA 353 Query: 1425 YESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEY--DTSVFDVSEI 1482 Y +D F G V E ++ + ++ PG G+++ + + +++ +++ Sbjct: 354 Y----VDNIRF-GDCRAVVHELSSGPVRDFHINSYGTPGTPDGVQLVFSGNPALYTATDL 408 Query: 1483 ETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFA 1542 +RF R L+A+ DP ++ R +L + + P ++PE+FA Sbjct: 409 ADHQERFLRFLDAVTADPDLPTGRHRLLSPGTRARLLDDSRGTERPVP---RATLPELFA 465 Query: 1543 RQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAI 1602 Q R P+APAV +G L Y +L + + A LA G VAL +P+SA+++ + Sbjct: 466 EQARRTPDAPAVQHDGTVLTYRDLHRSVERAAGRLAGLGLRTEDVVALALPKSAESVAIL 525 Query: 1603 LAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVD--DPA 1660 L + + GAAY+P+DP+ PA RL +L D +P VTTG + DG ++ D Sbjct: 526 LGIQRAGAAYVPLDPTHPAERLARVLDDTRPRYLVTTGHI----DGLSHPTPQLAAADLL 581 Query: 1661 VEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWS 1720 E P P+P + AY+I TSG+TG PKGV +TH + + GP A Sbjct: 582 REGGPEPAPGRPAPGNAAYIIQTSGSTGRPKGVVVTHEGLATLAADQIRRYRTGPDARVL 641 Query: 1721 QWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMM 1780 Q+ S FDV V E+ LL GG LVI P+ + G L L +E V TP A+ M Sbjct: 642 QFISPGFDVFVSELSMTLLSGGCLVIPPDGLTGR--HLADFLAAEAVTTTSLTPGALATM 699 Query: 1781 SPEGLEGT-ALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPI 1839 L L+V GE CP E+ D+W R ++NAYGPTE+T+ A VP+ Sbjct: 700 PATDLPHLRTLIVGGEVCPPEIFDQWGRGRDIVNAYGPTETTVEATAWHRDGATHGPVPL 759 Query: 1840 GSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGAR 1899 G P +VLD L PVP G GELYLA T RFVA PFG PG+R Sbjct: 760 GRPTLNRRGYVLDPALEPVPDGTTGELYLAGEGLARGYVAAPGPTAERFVADPFGPPGSR 819 Query: 1900 MYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRP 1959 MYRTGDLVR G L+++GRAD QVK+RG+RIELGE+QAAL+ + GV QA V+ REDRP Sbjct: 820 MYRTGDLVRRRSGGMLEFVGRADGQVKLRGFRIELGEVQAALTALPGVRQAGVLIREDRP 879 Query: 1960 GDKRLVGYITGT--ADPAAA--RSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPA 2015 GD RLVGYI A+P A R+ L LP +MVP A+V L LPLT NGKLDR ALP Sbjct: 880 GDPRLVGYIVPAPGAEPDAGELRAALARTLPPHMVPWALVPLPALPLTSNGKLDRAALPV 939 Query: 2016 PEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTAL 2075 P ++ + P T EKTL +FA VLGV R+ A + T Sbjct: 940 PAARAGGSGQRPVTPQEKTLCALFADVLGVTEVATDDVFFELGGHSLNGTRLLARIRTEF 999 Query: 2076 DADLSVRTLFEAPTVAKL 2093 DL++R LF PTVA L Sbjct: 1000 GTDLTLRDLFAFPTVAGL 1017 Score = 405 bits (1042), Expect = e-110 Identities = 305/823 (37%), Positives = 422/823 (51%), Gaps = 69/823 (8%) Query: 14 DLLDEDEHDQIEVWGNRA---VLTDPGP---TPVTIPALFAEQVVRAPDAVALVSGDRSW 67 D+L E + + WG A V PG + LF E+V PDAVA+ W Sbjct: 3044 DVLGAGERETLLGWGAGAEPGVRALPGAGAGAGAGLVGLFEERVRTDPDAVAVRGAGVEW 3103 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 +Y EL+ +N +A L G P V ++ R + + +L+V K+G YLPVDP P Sbjct: 3104 SYAELNARANAVARWLIGRGVGPERGVGVVMDRGPDVVAMLLAVAKSGGFYLPVDPQWPT 3163 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQY-DLAVIDMADPAIDRR--------PSDALSGP 178 RI ++++DA A+ +L + ++ D V+D A A + R D G Sbjct: 3164 ERIDWVLADAGIDLAVVGENLAAAVEAVRDCEVVDYAQIARETRLNEQAATDAGDVTDGE 3223 Query: 179 RPDDLA-----YMTYTSGTTGVPKAVAVTHHNVTQLVSA---LHADLPSGPGQVWSQWHS 230 R L Y+ YTSG+TG+PK V VTH +V + + G G V S S Sbjct: 3224 RVSALLSGHPLYVIYTSGSTGLPKGVVVTHASVGAYLRRGRNAYRGAADGLGHVHS---S 3280 Query: 231 LVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPS---AAGMLS 287 L FD++V ++ L+ GG + ++G D + L T L TPS G L Sbjct: 3281 LAFDLTVTVLFTPLVSGGCV-----TLGDLDDTANGLGAT----FLKATPSHLPLLGQLD 3331 Query: 288 PEGLESTTLIVAGEACPTELVDRWA---PGRVMINAYGPTEATIYAA---MSEPLXXXXX 341 TL++ GEA + W P +INAYGPTE T+ A + Sbjct: 3332 RVLAPDATLLLGGEALTAGALHHWRTHHPHTTVINAYGPTELTVNCAEYRIPPGHCLPDG 3391 Query: 342 XXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGE 401 LFVLD LR P +GELYVAG G+A GY+GRPDLTA RFVACPF Sbjct: 3392 PVPIGRPFTGHHLFVLDPALRLTPPDTIGELYVAGDGLARGYLGRPDLTAERFVACPFRS 3451 Query: 402 TGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAR 461 GERMYRTGDL RW SDG LE++GRAD+QVKIRG+RIELGE++AA+A V +A+ + R Sbjct: 3452 PGERMYRTGDLARWRSDGTLEFIGRADDQVKIRGFRIELGEVEAAVAAHPHVARAIAVVR 3511 Query: 462 EDRPGDKRLVGYITGTADPAQLRTALAES----LPAYMVPTAVVVLDTIPLTVNGKLDRR 517 EDRPGD+RLV Y+TG +DP+ L +A+ ++ LPAYMVP+AVVVLD IPLT NGK+DR Sbjct: 3512 EDRPGDQRLVAYVTG-SDPSGLSSAVTDTVAGRLPAYMVPSAVVVLDQIPLTPNGKVDRA 3570 Query: 518 ALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR 577 ALPAP S RAP T E+IL ++A VLG+++VGVD+ FFDLGG S+L+ ++ +R Sbjct: 3571 ALPAPGTASGTTS-RAPGTAREEILCTLFADVLGLDQVGVDEDFFDLGGHSLLATRLTSR 3629 Query: 578 ARAA-GIQCRPRDIFVEQTXXXXXXXXXXXXES----HVVDEGVG--PVVATPIMRW-LR 629 R+A GI R +F T S V E G P+ W L Sbjct: 3630 IRSALGIDLGVRALFKAPTVGRLDQLLQQQTTSLRAPLVARERTGCEPLSFAQQRLWFLH 3689 Query: 630 EVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDT-DEWSLLVP 688 +++GP +N + + + + L ++ RH +LR + Q+D+ W ++P Sbjct: 3690 QLEGPNAAYNIPMALRLTGRLDLTALEAALTDVIARHESLRTVI--AQDDSGGVWQNILP 3747 Query: 689 EAGAVGARECLRT--VDA--LTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIH 741 L T VDA L + V AR+ D + A R T L+L++H Sbjct: 3748 -TDDTRTHLTLDTMPVDAHTLQNRVDEAARHPFDLTTEIPLRATVFRVTDDEHVLLLVLH 3806 Query: 742 HLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSA 784 H+A DG S L DL+ A+ + +LPA +A ++A Sbjct: 3807 HIAGDGWSMAPLAHDLSAAYTVRLEHHAPQLPALAVQYADYAA 3849 Score = 386 bits (992), Expect = e-104 Identities = 247/615 (40%), Positives = 342/615 (55%), Gaps = 32/615 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQI-EVWGNRAVLTDPGPTPVTIPALFAEQVVRA----P 55 + A+P T L + LL +DE D+I WG+ TP+ P AEQ+VR P Sbjct: 5178 LAADP-TAPLGTVPLLTDDERDRILGDWGSGT------HTPLP-PRSVAEQIVRRAALDP 5229 Query: 56 DAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTG 115 DAVA+++ + +YREL+ S A +LA+ G + VA +PR+ + ++L VL+TG Sbjct: 5230 DAVAVITAEEELSYRELERLSGETARLLADRGIGRESLVAVALPRTAGLVTTLLGVLRTG 5289 Query: 116 AAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQ--YDLAVIDMADPAIDRRPSD 173 AAYLP+D +P R+ ++SDA+P LT A L RL ++D P P+ Sbjct: 5290 AAYLPLDTGYPAERLAHVLSDARPDLVLTHAGLAGRLPAGLAPTVLVDEPQPPAAAAPAV 5349 Query: 174 ALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVF 233 S P D LAY+ +TSG+TG PK VA+ ++ ++ P ++ F Sbjct: 5350 PTS-PSGDHLAYVIHTSGSTGRPKGVAIAESSLRAFLADAVRRHDLTPHDRLLAVTTVGF 5408 Query: 234 DVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPS-------AAGML 286 D++ E++ LL G +V+ E P + +L V+V+ TPS A Sbjct: 5409 DIAGLELFAPLLAGAAIVLADEDAVRDPASITSLCARHHVTVVQATPSWWRAMLDGAPAD 5468 Query: 287 SPEGLESTTLIVAGEACPTELVD-RWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXX 345 + LE ++V GE P +L A G + N YGPTEATI+A + Sbjct: 5469 AAARLEHVRILVGGEPLPADLARVLTATGAAVTNVYGPTEATIWATAAPLTAGDDRTPGI 5528 Query: 346 XXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 + +LD L P P GV GE+++AG G+A GY+ RPDLTA RFVA PF GER Sbjct: 5529 GTPLDNWRVHILDAALGPVPPGVPGEIHIAGSGLARGYLRRPDLTAERFVANPFAP-GER 5587 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDL R+ DG LE+LGR D+QVK+RG+RIELG+++AALA+ V +A R D Sbjct: 5588 MYRTGDLGRFRPDGTLEHLGRVDDQVKVRGFRIELGDVEAALARHPDVGRAAAAVRPDHR 5647 Query: 466 GDKRLVGYI-----TGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALP 520 G RLV Y+ T D +LR + E LP YMVP+A V L T+P T NGKLDR ALP Sbjct: 5648 GQGRLVAYVVPRPGTRGPDAGELRETVRELLPDYMVPSAQVTLTTLPHTPNGKLDRAALP 5707 Query: 521 APEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA 580 AP + + A RAP+T E+ILA ++A +LG+ VG D FFDLGGDS+LS+Q+V+RAR Sbjct: 5708 APVFGTPAG--RAPATREEKILAGLFADILGLPDVGADSGFFDLGGDSVLSIQLVSRARR 5765 Query: 581 AGIQCRPRDIFVEQT 595 G+ RD+F T Sbjct: 5766 EGLHITVRDVFEHGT 5780 >tr|D6AH54|D6AH54_STRFL Tax_Id=457431 SubName: Full=Peptide synthetase 1;[Streptomyces roseosporus NRRL 15998] Length = 5830 Score = 1330 bits (3443), Expect = 0.0 Identities = 851/2227 (38%), Positives = 1189/2227 (53%), Gaps = 183/2227 (8%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 R + S++LL +DE + W + A T PG T+ L + R PD A+V D Sbjct: 1468 RPISSYELLGDDERALLAQWNDTAHPTPPG----TVLDLLESRAARTPDRPAVVENDHVL 1523 Query: 68 TYRELDEASNRLA-HVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHP 126 TY +L +NRLA H++ HG P VA +PRS E ++++L+VLKTGAAY+P+D HP Sbjct: 1524 TYADLHTRANRLARHLITAHGVGPERLVAVALPRSAELLVALLAVLKTGAAYVPLDLTHP 1583 Query: 127 DARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPD----- 181 R ++ D +P LT A L + D+ + + +P + ++ GP D Sbjct: 1584 AERTAVVLDDCRPAVILTDAGAARELPRRDIPQLRLDEPEVHAAIAEQPGGPVTDRDRTC 1643 Query: 182 -------DLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFD 234 +AY+ YTSG+TG PK VAV H ++ V P G V + FD Sbjct: 1644 VTPVSGEHVAYVIYTSGSTGRPKGVAVEHRSLADFVRYSVTAYP-GAFDVTLLHSPVTFD 1702 Query: 235 VSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGL--- 291 ++V ++ L+ GG + V + P +L + + TPS +L+ E Sbjct: 1703 LTVTSLFPPLVVGGAIHVADLTEACPP----SLAAAGGPTFVKATPSHLPLLTHEATWAA 1758 Query: 292 ESTTLIVAGEACPTELVDRW---APGRVMINAYGPTEATIYAA-----MSEPLXXXXXXX 343 + L+V GE +D+W +P V+ N YGPTEAT+ +P+ Sbjct: 1759 SAKVLLVGGEQLLGRELDKWRAGSPEAVVFNDYGPTEATVNCVDFRIDPGQPIGAGPVAI 1818 Query: 344 XXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETG 403 +FVLD LR P GVVGEL+VAG G+A GY+G+P LTA RFVACPFG+ G Sbjct: 1819 GRPLRNTR--VFVLDGGLRAVPVGVVGELHVAGEGLARGYLGQPGLTAERFVACPFGDAG 1876 Query: 404 ERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIARED 463 ERMYRTGDLVRW +DG LE++GR D+QVK+RG+RIELGE++AA+A GVD++VV+ RED Sbjct: 1877 ERMYRTGDLVRWRADGMLEFVGRVDDQVKVRGFRIELGEVEAAVAACPGVDRSVVVVRED 1936 Query: 464 RPGDKRLVGYITGTADPAQLRTAL-----AESLPAYMVPTAVVVLDTIPLTVNGKLDRRA 518 RPGD+RLV Y+T D A+ L A LP YMVP+AVVVLD IPLT NGK+DR A Sbjct: 1937 RPGDRRLVAYVTAAGDEAEGLAPLIVETAAGRLPGYMVPSAVVVLDEIPLTPNGKVDRAA 1996 Query: 519 LPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARA 578 LPAP AA ++R +P E+ L ++A+VLGVERVGVDD FFDLGGDSILS+Q+VARA Sbjct: 1997 LPAPRVAPAA-EFRVTGSPREEALCALFAEVLGVERVGVDDGFFDLGGDSILSIQLVARA 2055 Query: 579 RAAGIQCRPRDIFVEQTXXXXXXXXXXXX--ESHVVDEGVGPVVATPIMRWLRE-----V 631 R AG++ RD+F +T + VVD GVG V P++ WL E + Sbjct: 2056 RRAGLEVSVRDVFEHRTVRALAGVVRESGGVAAAVVDSGVGAVERWPVVEWLAERGGGGL 2115 Query: 632 DGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAG 691 G FNQ+V+ PAG+T D++ +L A+ +RH RLRV D+ + WSL V Sbjct: 2116 GGAVRAFNQSVVVATPAGITWDELRTVLDAVRERHDAWRLRVVDSGDGA--WSLRVDAPA 2173 Query: 692 AVGARECLRTVDALTDDV----------LVEARNRLDPAAGAMVSAVWVRETSQ----LV 737 G + + + D+ VEAR+RLDP G MV AVW+ LV Sbjct: 2174 PGGEPDWITRHGMASADLEEQVNAVRAAAVEARSRLDPLTGRMVRAVWLDRGPDRRGVLV 2233 Query: 738 LMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRD 797 L+ HHL VDGVSWRI+L DL AW Q G + L GTS W+A LAE + Sbjct: 2234 LVAHHLVVDGVSWRIVLGDLGEAWTQARAGGHVRLDTVGTSLRGWAAALAEQGRHGARAT 2293 Query: 798 LADAWRAVT--SVPQALP-PVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQD 854 A+ W + S P P V P D + + + V +R LL EVP+ GVQ+ Sbjct: 2294 EANLWAQMVHGSDPLVGPRAVDPSVDVFGVVESVGSRASVGVSRALLTEVPSVLGVGVQE 2353 Query: 855 ILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENL 914 +LL AFGLA T + R + + VDVEGHGR ++ DLSRTVGWFT+ YPV L +E Sbjct: 2354 VLLAAFGLAVTRWRGRGGSVV-VDVEGHGRNEDAVPGADLSRTVGWFTSIYPVRLPLEPA 2412 Query: 915 PWEQVVAGDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEVDLGGSD---PTIGFNYL 970 W+++ AG A+G V+ +KE LR+LP+ GL YG+LRYL+PE + P GFNYL Sbjct: 2413 AWDEIRAGGPAVGRTVREIKECLRTLPDQGLGYGILRYLDPENGPALAQHPTPHFGFNYL 2472 Query: 971 GRL------------------------GAGAGELSEELWR--IDQXXXXXXXXXXXVPMP 1004 GR+ G A + EE W + +P Sbjct: 2473 GRVSVSADAASLDEGDAHADGLGGLVGGRAAADSDEEQWADWVPVSGPFAVGAGQDPVLP 2532 Query: 1005 LMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRG-GGG 1063 + H VE NA T+DT +GP L +W+W + E + L+R W EAL G+ AH R G Sbjct: 2533 VAHAVEFNAITLDTPDGPRLSVTWSWPTTLLSESRIRELARFWDEALEGLVAHARRPDAG 2592 Query: 1064 GLTPSDVAPARLTQRQIDELSQRYDVT----DVLPLTPVQQGLLFHSTFARGIGDDVYAV 1119 GLTPSD+ L +++ L DVT D+LP++P+Q+GLLFHS+FA G DVY Sbjct: 2593 GLTPSDLPLVALDHAELEALQA--DVTGGVHDILPVSPLQEGLLFHSSFAAD-GVDVYVG 2649 Query: 1120 QLDITITGVLDQHRLRDAVHTVVARHPNLAARFVE-QFGEPVQVLTADPMIAWRYLDLRG 1178 QL +TG +D L V ++V RH L + + Q GE + V+ W+Y+ Sbjct: 2650 QLTFDLTGPVDADHLHAVVESLVTRHDVLRTGYRQAQSGEWIAVVARQVHTPWQYIH--- 2706 Query: 1179 DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPIL 1238 T D + + L ER D+ + P R L R + RF++T+HH+++DGWS+ +L Sbjct: 2707 ---TLDTDADTLTNDERWRPFDMTQGPLARFTLARINDTHFRFIVTYHHVILDGWSVAVL 2763 Query: 1239 LQEIFAGY----FGHR--LPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPP 1292 ++E+F Y G R +P + P R+F+ WL WR L G PT++A Sbjct: 2764 IRELFTTYRDTALGRRPEVPYSPPRRDFMAWLAERDQTAAGQAWRSALAGLAEPTVLAL- 2822 Query: 1293 GVPG----PRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFG 1348 G G P +E +S E T L AR + T+ +V+QAAW +L R+ G+ DV FG Sbjct: 2823 GTEGSGVIPEVLEE-EISEELTSELVAWARGRGVTVASVVQAAWALVLGRLVGRDDVVFG 2881 Query: 1349 TAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALND 1408 VSGRPA++AG E MVGL +NT+P+RA++ ++G + +LQ + LEH+H+ L + Sbjct: 2882 LTVSGRPAEVAGVEDMVGLFVNTIPLRARMDPAESLGAFVERLQREQTELLEHQHVRLAE 2941 Query: 1409 IHHVSGHEQLFDTLFLYESYPIDT----SAFMGVQELAVTEFNNREYNHYPLSVMALPGH 1464 + +GH++LFD ++E+YP+D+ S F G L + + H+ L++ +P Sbjct: 2942 VQRWAGHKELFDVGMVFENYPMDSLLQDSLFHG-SGLQIDGIQGADATHFALNLAVVPLP 3000 Query: 1465 ELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWAN- 1523 + R+ Y VFD + L R LE ++ + +S +DV+ ER L W Sbjct: 3001 AMRFRLGYRPDVFDAGRVRELWGWIVRALECVVCERDVPVSGVDVLGAGERETLLGWGAG 3060 Query: 1524 -----RAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLA 1578 RA+ + + +F +V DP+A AV G +Y EL+ AN +A L Sbjct: 3061 AEPGVRALPGAGAGAGAGLVGLFEERVRTDPDAVAVRGAGVEWSYAELNARANAVARWLI 3120 Query: 1579 VYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVT 1638 G P + V +++ R D + +LAV K+G YLP+DP P R++++L DA AV Sbjct: 3121 GRGVGPERGVGVVMDRGPDVVAMLLAVAKSGGFYLPVDPQWPTERIDWVLADAGIDLAVV 3180 Query: 1639 TGDLRSRFDGF-DLQVVEVDDPAVEIYPSTTLLTPSPDDI-------------AYMIYTS 1684 +L + + D +VV+ A E + T + D Y+IYTS Sbjct: 3181 GENLAAAVEAVRDCEVVDYAQIARETRLNEQAATDAGDVTDGERVSALLSGHPLYVIYTS 3240 Query: 1685 GTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRL 1744 G+TG+PKGV +TH +V L + SL FD++V ++ L+ GG + Sbjct: 3241 GSTGLPKGVVVTHASVGAYLRRGRNAYRGAADGLGHVHSSLAFDLTVTVLFTPLVSGGCV 3300 Query: 1745 VIVPESIAGSPDDLHALLVSEGVNVLYQTPSAV-------RMMSPEGLEGTALVVAGEAC 1797 + G DD L G L TPS + R+++P+ L++ GEA Sbjct: 3301 TL------GDLDDTANGL---GATFLKATPSHLPLLGQLDRVLAPDA----TLLLGGEAL 3347 Query: 1798 PTEVVDRWAVDR---VMINAYGPTESTIYAAISAPLSPGSDV----VPIGSPVPKGATFV 1850 + W +INAYGPTE T+ A + PG + VPIG P FV Sbjct: 3348 TAGALHHWRTHHPHTTVINAYGPTELTVNCA-EYRIPPGHCLPDGPVPIGRPFTGHHLFV 3406 Query: 1851 LDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWG 1910 LD LR PP +GELY+A LT RFVACPF PG RMYRTGDL RW Sbjct: 3407 LDPALRLTPPDTIGELYVAGDGLARGYLGRPDLTAERFVACPFRSPGERMYRTGDLARWR 3466 Query: 1911 DDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITG 1970 DG L+++GRAD+QVKIRG+RIELGE++AA++ V +A+ + REDRPGD+RLV Y+TG Sbjct: 3467 SDGTLEFIGRADDQVKIRGFRIELGEVEAAVAAHPHVARAIAVVREDRPGDQRLVAYVTG 3526 Query: 1971 TADPAAARSELTN----RLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRA 2026 +DP+ S +T+ RLPAYMVP+AVV L+ +PLT NGK+DR ALPAP S RA Sbjct: 3527 -SDPSGLSSAVTDTVAGRLPAYMVPSAVVVLDQIPLTPNGKVDRAALPAPGTASGTTSRA 3585 Query: 2027 PETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFE 2086 P T E+ L +FA VLG+++ A R+T+ + +AL DL VR LF+ Sbjct: 3586 PGTAREEILCTLFADVLGLDQVGVDEDFFDLGGHSLLATRLTSRIRSALGIDLGVRALFK 3645 Query: 2087 APTVAKL 2093 APTV +L Sbjct: 3646 APTVGRL 3652 Score = 489 bits (1259), Expect = e-135 Identities = 358/1041 (34%), Positives = 496/1041 (47%), Gaps = 76/1041 (7%) Query: 1117 YAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPV--QVLTADPMIAWRYL 1174 Y + + + +TG LD L A+ V+ARH +L + V +L D L Sbjct: 3698 YNIPMALRLTGRLDLTALEAALTDVIARHESLRTVIAQDDSGGVWQNILPTDDTRTHLTL 3757 Query: 1175 DLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWS 1234 D D H ++ DL RA + R + ++H +L HHI DGWS Sbjct: 3758 DTMPVDA---HTLQNRVDEAARHPFDLTTEIPLRATVFRVTDDEHVLLLVLHHIAGDGWS 3814 Query: 1235 LPILLQEIFAGY------FGHRLPA-AAPYRNFVNWLXXXXXXXXXXX---------WRE 1278 + L ++ A Y +LPA A Y ++ W W Sbjct: 3815 MAPLAHDLSAAYTVRLEHHAPQLPALAVQYADYAAWQRDVLGTENNTSSQLSTQLDYWYS 3874 Query: 1279 VLDGFET----PTLVAPPGVPGPRGIE-SYRVSAETTRALGELARSQHTTINTVLQAAWT 1333 L+G PT P V + V + + L LAR+Q T+ V+QAA Sbjct: 3875 KLEGLPAELTLPTSRVRPAVASHACDRVEFTVPHDVHQGLTALARTQGATVFMVVQAALA 3934 Query: 1334 QLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQS 1393 LL R+ D+ GT ++GR E+++GL +NT+ +R VS D T +LL ++++ Sbjct: 3935 ALLSRLGAGTDIPIGTPIAGRTDQ--AMENLIGLFVNTLVLRTDVSGDPTFAELLARVRT 3992 Query: 1394 HHNDTLEHEHL-------ALNDIHHVSGHEQLFDTLFLYESYPIDTS-----AFMGVQEL 1441 D H+ + A+N ++ H LF + + + ++ A G+ Sbjct: 3993 TALDAYAHQDIPFERLVEAINPERSLTRHP-LFQVMLAFNNTDRRSALDALDAMPGLHAR 4051 Query: 1442 AVTEFNNREYNHYPLSVMALPGH-ELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP 1500 S + PG E+ ++Y T +FD S E + +R RLL + P Sbjct: 4052 PADVLAVTSPYDLAFSFVETPGSTEMPGILDYATDLFDRSTAEAMTERLVRLLAEIARRP 4111 Query: 1501 ARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES 1560 + + ++ DE L A A + +PE+F QV A AV EGE Sbjct: 4112 ELSVGDIGILSADEVKALSPEAPPAAEELHTST---LPELFEEQVAARGHAVAVVCEGEE 4168 Query: 1561 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVP 1620 L+Y EL+ AN+LA +L GA P + V + +PR D IVA+LAV KTGAAY+P+DP P Sbjct: 4169 LSYKELNARANRLARVLMERGAGPERFVGVALPRGLDLIVALLAVTKTGAAYVPLDPEYP 4228 Query: 1621 AARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVEIY----PSTTLLTPS-PD 1675 RL +M+ DA P A VT+ D+ +E+DD A+ P T S P Sbjct: 4229 TDRLAYMVTDANPTAVVTSTDVHIPLIA---PRIELDDEAIRTELAAAPDTAPCVGSGPA 4285 Query: 1676 DIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIW 1735 AY+IYTSG+TG PKGV I+H NV ++ GP VW+ +HS FD SVWEIW Sbjct: 4286 HPAYVIYTSGSTGRPKGVVISHANVVRLFTACSDSFDFGPDHVWTLFHSYAFDFSVWEIW 4345 Query: 1736 GALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS------PEGLEGTA 1789 GALLHGGRLV+VP + SP + ALL + V +L QTPSA ++ P G A Sbjct: 4346 GALLHGGRLVVVPFEVTRSPAEFLALLAEQQVTLLSQTPSAFHQLTEAARQEPARCAGLA 4405 Query: 1790 L---VVAGEACPTEVVDRW-----AVDRVMINAYGPTESTIYAAISAPLSPGSDVV---P 1838 L V GEA + W ++N YG TE+T++ + PL + + P Sbjct: 4406 LRHVVFGGEALDPSRLRDWFDLPLGSRPTLVNMYGITETTVHVTV-LPLEDRATSLSGSP 4464 Query: 1839 IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGA 1898 IG P+ +VLDE LRPVPPG VGE+Y+A LT RFVA P G Sbjct: 4465 IGRPLADLQVYVLDERLRPVPPGTVGEMYVAGAGLARGYLGRPALTAERFVADPNSRSGG 4524 Query: 1899 RMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDR 1958 R+YRTGDL + DG L+Y+GR D QVKIRG+RIELGEI+AAL GV QAVV+ R+++ Sbjct: 4525 RLYRTGDLAKVRPDGGLEYVGRGDRQVKIRGFRIELGEIEAALVTHAGVVQAVVLVRDEQ 4584 Query: 1959 PGDKRLVGYITGTADP-----AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRAL 2013 D+RLV ++ A L LPAYMVP+A TL+ LPLT NGKLDR AL Sbjct: 4585 TDDQRLVAHVVPALPHRAPTLAELHEHLAATLPAYMVPSAYRTLDELPLTANGKLDRAAL 4644 Query: 2014 PAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNT 2073 + R P T E+ L +FA VL + A R+ +AV Sbjct: 4645 AGQWQGGTRTRRLPRTPQEEILCELFADVLRLPAAGADDDFFALGGHSLLATRLLSAVRG 4704 Query: 2074 ALDADLSVRTLFEAPTVAKLS 2094 L +L +R LF APT A L+ Sbjct: 4705 TLGVELGIRDLFAAPTPAGLA 4725 Score = 470 bits (1210), Expect = e-129 Identities = 359/1070 (33%), Positives = 520/1070 (48%), Gaps = 84/1070 (7%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+ QQ L F Y + + + G LD L A+ V RH L Sbjct: 1040 LPLSHAQQRLWFLDQVEGP--SPAYNIPTAVRLEGPLDIPALAVALQDVTNRHEPLRTLL 1097 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALI 1212 E P QV+ P A R +L + P L A R DL +A L Sbjct: 1098 AEDSEGPHQVIL--PPEAARP-ELTHSTVAPGDLAAALAEAARRPF-DLAGEIPLKAHLF 1153 Query: 1213 RTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNFV---- 1261 + H +L HH DG S+ +L++++ Y R P Y + Sbjct: 1154 GCGPDDHTLLLLVHHTAGDGASVEVLVRDLAHAYGARRAGDAPHFEPLPLQYADHTLRRR 1213 Query: 1262 NWLXXXXXXXXXXXWREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAETTRALGEL 1316 + L WR+ L G E PT P VP RG ++ V T L + Sbjct: 1214 HLLDDPSDSTQLDHWRDALAGLPEQLELPTDHTRPAVPTRRGEAIAFTVPEHTHHTLRAM 1273 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA 1376 A++ T+ V+QAA LL R D+ GT V+GR D G E +VG +NT+ +R Sbjct: 1274 AQAHGVTVFMVMQAALAALLSRHGAGHDIPLGTPVAGRSDD--GTEDLVGFFVNTLVLRN 1331 Query: 1377 KVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQ------LFDTLFLYE---- 1426 VS D T +L+ ++++ + D ++ + + V E+ LF + Y Sbjct: 1332 DVSGDPTFAELVSRVRAANLDAYAYQDVPFERLVDVLKPERSLSWHPLFQIMIAYNGPAT 1391 Query: 1427 SYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRV----EYDTSVFDVSEI 1482 + D S F G+ + + LS L H GL + E+ T +F Sbjct: 1392 NDTADGSRFAGLTSRVHAVHTGM--SKFDLSFF-LTEHADGLGIDGALEFSTDLFTRITA 1448 Query: 1483 ETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFA 1542 E L+ R+ +LE P R +SS +++ DDER L +W + A T P ++ ++ Sbjct: 1449 ERLVQRYLTVLEQAAGAPDRPISSYELLGDDERALLAQWNDTAHPTPP----GTVLDLLE 1504 Query: 1543 RQVERDPEAPAVTFEGESLNYGELDEAANQLA-NLLAVYGAAPGKSVALMVPRSADAIVA 1601 + R P+ PAV L Y +L AN+LA +L+ +G P + VA+ +PRSA+ +VA Sbjct: 1505 SRAARTPDRPAVVENDHVLTYADLHTRANRLARHLITAHGVGPERLVAVALPRSAELLVA 1564 Query: 1602 ILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAV 1661 +LAVLKTGAAY+P+D + PA R +L D +P +T D+ + +D+P V Sbjct: 1565 LLAVLKTGAAYVPLDLTHPAERTAVVLDDCRPAVILTDAGAARELPRRDIPQLRLDEPEV 1624 Query: 1662 EIY-------PST----TLLTP-SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPA 1709 P T T +TP S + +AY+IYTSG+TG PKGVA+ H ++ D + Sbjct: 1625 HAAIAEQPGGPVTDRDRTCVTPVSGEHVAYVIYTSGSTGRPKGVAVEHRSLA---DFVRY 1681 Query: 1710 ELPAGPGAV-WSQWHSLV-FDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 + A PGA + HS V FD++V ++ L+ GG + + + A P +L + G Sbjct: 1682 SVTAYPGAFDVTLLHSPVTFDLTVTSLFPPLVVGGAIHVADLTEACPP----SLAAAGGP 1737 Query: 1768 NVLYQTPSAVRMMSPEGL---EGTALVVAGEACPTEVVDRWAV---DRVMINAYGPTEST 1821 + TPS + +++ E L+V GE +D+W + V+ N YGPTE+T Sbjct: 1738 TFVKATPSHLPLLTHEATWAASAKVLLVGGEQLLGRELDKWRAGSPEAVVFNDYGPTEAT 1797 Query: 1822 IYAAISAPLSPGSDV----VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXX 1877 + + + PG + V IG P+ FVLD LR VP GVVGEL++A Sbjct: 1798 VNC-VDFRIDPGQPIGAGPVAIGRPLRNTRVFVLDGGLRAVPVGVVGELHVAGEGLARGY 1856 Query: 1878 XXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEI 1937 LT RFVACPFG+ G RMYRTGDLVRW DG L+++GR D+QVK+RG+RIELGE+ Sbjct: 1857 LGQPGLTAERFVACPFGDAGERMYRTGDLVRWRADGMLEFVGRVDDQVKVRGFRIELGEV 1916 Query: 1938 QAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSEL-----TNRLPAYMVPA 1992 +AA++ GVD++VV+ REDRPGD+RLV Y+T D A + L RLP YMVP+ Sbjct: 1917 EAAVAACPGVDRSVVVVREDRPGDRRLVAYVTAAGDEAEGLAPLIVETAAGRLPGYMVPS 1976 Query: 1993 AVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXX 2052 AVV L+ +PLT NGK+DR ALPAP A +R + E+ L +FA VLGVER Sbjct: 1977 AVVVLDEIPLTPNGKVDRAALPAPRVAPAAEFRVTGSPREEALCALFAEVLGVERVGVDD 2036 Query: 2053 XXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAG 2102 ++++ A A ++SVR +FE TV L+ V G Sbjct: 2037 GFFDLGGDSILSIQLVARARRA-GLEVSVRDVFEHRTVRALAGVVRESGG 2085 Score = 449 bits (1154), Expect = e-123 Identities = 331/939 (35%), Positives = 467/939 (49%), Gaps = 70/939 (7%) Query: 42 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRS 101 T+P LF EQV AVA+V +Y+EL+ +NRLA VL E GA P V +PR Sbjct: 4144 TLPELFEEQVAARGHAVAVVCEGEELSYKELNARANRLARVLMERGAGPERFVGVALPRG 4203 Query: 102 GEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLR-----SRLDQYD 156 + I+++L+V KTGAAY+P+DP +P R+ +M++DA P A +T+ D+ R++ D Sbjct: 4204 LDLIVALLAVTKTGAAYVPLDPEYPTDRLAYMVTDANPTAVVTSTDVHIPLIAPRIELDD 4263 Query: 157 LAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHAD 216 A+ A D P G P AY+ YTSG+TG PK V ++H NV +L +A Sbjct: 4264 EAIRTELAAAPDTAPC---VGSGPAHPAYVIYTSGSTGRPKGVVISHANVVRLFTACSDS 4320 Query: 217 LPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVL 276 GP VW+ +HS FD SVWEIWGALLHGGRLVVVP V SP + LL ++V++L Sbjct: 4321 FDFGPDHVWTLFHSYAFDFSVWEIWGALLHGGRLVVVPFEVTRSPAEFLALLAEQQVTLL 4380 Query: 277 CQTPSAAGMLSPE---------GLESTTLIVAGEACPTELVDRW-----APGRVMINAYG 322 QTPSA L+ GL ++ GEA + W ++N YG Sbjct: 4381 SQTPSAFHQLTEAARQEPARCAGLALRHVVFGGEALDPSRLRDWFDLPLGSRPTLVNMYG 4440 Query: 323 PTEATIYAAMS--EPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVA 380 TE T++ + E ++VLD+ LRP P G VGE+YVAG G+A Sbjct: 4441 ITETTVHVTVLPLEDRATSLSGSPIGRPLADLQVYVLDERLRPVPPGTVGEMYVAGAGLA 4500 Query: 381 TGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIEL 440 GY+GRP LTA RFVA P +G R+YRTGDL + DG LEY+GR D QVKIRG+RIEL Sbjct: 4501 RGYLGRPALTAERFVADPNSRSGGRLYRTGDLAKVRPDGGLEYVGRGDRQVKIRGFRIEL 4560 Query: 441 GEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP-----AQLRTALAESLPAYM 495 GEI+AAL GV QAVV+ R+++ D+RLV ++ A+L LA +LPAYM Sbjct: 4561 GEIEAALVTHAGVVQAVVLVRDEQTDDQRLVAHVVPALPHRAPTLAELHEHLAATLPAYM 4620 Query: 496 VPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERV 555 VP+A LD +PLT NGKLDR AL A +++ R P TP E+IL +++A VL + Sbjct: 4621 VPSAYRTLDELPLTANGKLDRAAL-AGQWQGGTRTRRLPRTPQEEILCELFADVLRLPAA 4679 Query: 556 GVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXXXXXXXXXXES----H 610 G DD FF LGG S+L+ ++++ R G++ RD+F T + Sbjct: 4680 GADDDFFALGGHSLLATRLLSAVRGTLGVELGIRDLFAAPTPAGLATVLAASGTALPPVT 4739 Query: 611 VVD---EGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHA 667 +D E + A + +L +++GP+ +N V + + + L + RH Sbjct: 4740 RIDRRPERLPLSFAQRRLWFLSKLEGPSATYNIPVAVRLTGALDVPALRAALGDVTARHE 4799 Query: 668 TLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSA 727 +LR D + + L++P A + TV + + D + + A Sbjct: 4800 SLRTVFPD--DGGEPRQLVLPHAEPPFLTHEV-TVGEVAEQAASATGYAFDITSDTPLRA 4856 Query: 728 VWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFAR 781 +R E LV++IHH+A DG S L+ DL A+ G + E LP +A Sbjct: 4857 TLLRVSPEEHVLVVVIHHIAGDGWSMGPLVRDLVTAYRARTRGDAPEYTPLPVQYADYAL 4916 Query: 782 WSALLA--EHAKTDTVRDLADAWR-AVTSVPQ--ALPPVQP-DTDTYVTAGQLSASLDVE 835 W +A E A WR + +P+ LP +P + G++ L Sbjct: 4917 WQHAVAGDEDAPDGRTARRLGYWREMLAGLPEEHTLPADRPRPVRSSHRGGRVRFELPAG 4976 Query: 836 TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLS 895 R LL V RA + ++ A + D PIG V G G DE DV Sbjct: 4977 VHRSLLA-VARDRRATLFMVVQAALAGLLSRLGAGDDIPIGTPVAGRG--DEALDDV--- 5030 Query: 896 RTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVK 934 VG+F V L +AGD + +V V+ Sbjct: 5031 --VGFF---------VNTLVLRTNLAGDPSFADLVDRVR 5058 Score = 442 bits (1138), Expect = e-121 Identities = 332/1012 (32%), Positives = 481/1012 (47%), Gaps = 81/1012 (8%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+ Q+ L F S Y + + + +TG LD LR A+ V ARH +L F Sbjct: 4748 LPLSFAQRRLWFLSKLEGPSA--TYNIPVAVRLTGALDVPALRAALGDVTARHESLRTVF 4805 Query: 1153 VEQFGEPVQVLT--ADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 + GEP Q++ A+P + + E+ + A+ D+ RA Sbjct: 4806 PDDGGEPRQLVLPHAEPPFLTHEVTVG--------EVAEQAASATGYAFDITSDTPLRAT 4857 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHR-------LPAAAPYRNFVNW 1263 L+R S +H V+ HHI DGWS+ L++++ Y P Y ++ W Sbjct: 4858 LLRVSPEEHVLVVVIHHIAGDGWSMGPLVRDLVTAYRARTRGDAPEYTPLPVQYADYALW 4917 Query: 1264 ---------LXXXXXXXXXXXWREVLDGF-ETPTLVAPPGVPGPRGIES--------YRV 1305 WRE+L G E TL A PR + S + + Sbjct: 4918 QHAVAGDEDAPDGRTARRLGYWREMLAGLPEEHTLPADR----PRPVRSSHRGGRVRFEL 4973 Query: 1306 SAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMV 1365 A R+L +AR + T+ V+QAA LL R+ D+ GT V+GR + + +V Sbjct: 4974 PAGVHRSLLAVARDRRATLFMVVQAALAGLLSRLGAGDDIPIGTPVAGRGDE--ALDDVV 5031 Query: 1366 GLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLY 1425 G +NT+ +R ++ D + DL+ ++++ D H+ + + + L+ Sbjct: 5032 GFFVNTLVLRTNLAGDPSFADLVDRVRTADLDAFAHQDVPFERLVEALAPRRSLARHPLF 5091 Query: 1426 ESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALP--------------GHELGLRV- 1470 + + T+A + A+ + YPL A G GL V Sbjct: 5092 QIWYTLTNADQDITGQALNALPGLTGDEYPLGASAAKFDLSFTFTEHRTPDGDAAGLSVL 5151 Query: 1471 -EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQ-LDEWANRAVLT 1528 +Y + ++D L R A+ DP L ++ ++ DDER + L +W + Sbjct: 5152 LDYSSDLYDHGTAAALGHRLTGFFAALAADPTAPLGTVPLLTDDERDRILGDWGSGTHTP 5211 Query: 1529 QPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSV 1588 P P+S+ E R+ DP+A AV E L+Y EL+ + + A LLA G V Sbjct: 5212 LP---PRSVAEQIVRRAALDPDAVAVITAEEELSYRELERLSGETARLLADRGIGRESLV 5268 Query: 1589 ALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDG 1648 A+ +PR+A + +L VL+TGAAYLP+D PA RL +L DA+P +T L R Sbjct: 5269 AVALPRTAGLVTTLLGVLRTGAAYLPLDTGYPAERLAHVLSDARPDLVLTHAGLAGRLPA 5328 Query: 1649 FDLQVVEVDDPAVEIYPSTTLLT-PSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL 1707 V VD+P + + T PS D +AY+I+TSG+TG PKGVAI ++ L Sbjct: 5329 GLAPTVLVDEPQPPAAAAPAVPTSPSGDHLAYVIHTSGSTGRPKGVAIAESSLRAFLADA 5388 Query: 1708 PAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGV 1767 P ++ FD++ E++ LL G +V+ E P + +L V Sbjct: 5389 VRRHDLTPHDRLLAVTTVGFDIAGLELFAPLLAGAAIVLADEDAVRDPASITSLCARHHV 5448 Query: 1768 NVLYQTPSAVRMM-------SPEGLEGTALVVAGEACPTEVVD-RWAVDRVMINAYGPTE 1819 V+ TPS R M + LE ++V GE P ++ A + N YGPTE Sbjct: 5449 TVVQATPSWWRAMLDGAPADAAARLEHVRILVGGEPLPADLARVLTATGAAVTNVYGPTE 5508 Query: 1820 STIYAAISAPLSPGSDVVP-IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXX 1878 +TI+A +APL+ G D P IG+P+ +LD L PVPPGV GE+++A Sbjct: 5509 ATIWAT-AAPLTAGDDRTPGIGTPLDNWRVHILDAALGPVPPGVPGEIHIAGSGLARGYL 5567 Query: 1879 XXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQ 1938 LT RFVA PF PG RMYRTGDL R+ DG L++LGR D+QVK+RG+RIELG+++ Sbjct: 5568 RRPDLTAERFVANPFA-PGERMYRTGDLGRFRPDGTLEHLGRVDDQVKVRGFRIELGDVE 5626 Query: 1939 AALSDVDGVDQAVVIAREDRPGDKRLVGYIT---GTADPAAA--RSELTNRLPAYMVPAA 1993 AAL+ V +A R D G RLV Y+ GT P A R + LP YMVP+A Sbjct: 5627 AALARHPDVGRAAAAVRPDHRGQGRLVAYVVPRPGTRGPDAGELRETVRELLPDYMVPSA 5686 Query: 1994 VVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGV 2045 VTL TLP T NGKLDR ALPAP + RAP T EK LAG+FA +LG+ Sbjct: 5687 QVTLTTLPHTPNGKLDRAALPAPVF-GTPAGRAPATREEKILAGLFADILGL 5737 Score = 436 bits (1121), Expect = e-119 Identities = 329/935 (35%), Positives = 443/935 (47%), Gaps = 54/935 (5%) Query: 28 GNRAVLTDPG-----PTP-VTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAH 81 G RA L D P P T+P LFAEQ R PDA A+ TYR+L + R A Sbjct: 439 GTRARLLDDSRGTERPVPRATLPELFAEQARRTPDAPAVQHDGTVLTYRDLHRSVERAAG 498 Query: 82 VLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVA 141 LA G + VA +P+S E++ +L + + GAAY+P+DP HP R+ ++ D +P Sbjct: 499 RLAGLGLRTEDVVALALPKSAESVAILLGIQRAGAAYVPLDPTHPAERLARVLDDTRPRY 558 Query: 142 ALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAV 201 +TT + + + AD + P A P P + AY+ TSG+TG PK V V Sbjct: 559 LVTTGHIDGL--SHPTPQLAAADLLREGGPEPAPGRPAPGNAAYIIQTSGSTGRPKGVVV 616 Query: 202 THHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSP 261 TH + L + +GP Q+ S FDV V E+ LL GG LV+ P+ G + Sbjct: 617 THEGLATLAADQIRRYRTGPDARVLQFISPGFDVFVSELSMTLLSGGCLVIPPD--GLTG 674 Query: 262 DDLHNLLITEKVSVLCQTPSAAGMLSPEGLEST-TLIVAGEACPTELVDRWAPGRVMINA 320 L + L E V+ TP A + L TLIV GE CP E+ D+W GR ++NA Sbjct: 675 RHLADFLAAEAVTTTSLTPGALATMPATDLPHLRTLIVGGEVCPPEIFDQWGRGRDIVNA 734 Query: 321 YGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVA 380 YGPTE T+ A +VLD L P P+G GELY+AG G+A Sbjct: 735 YGPTETTVEATAWHRDGATHGPVPLGRPTLNRRGYVLDPALEPVPDGTTGELYLAGEGLA 794 Query: 381 TGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIEL 440 GY+ P TA RFVA PFG G RMYRTGDLVR S G LE++GRAD QVK+RG+RIEL Sbjct: 795 RGYVAAPGPTAERFVADPFGPPGSRMYRTGDLVRRRSGGMLEFVGRADGQVKLRGFRIEL 854 Query: 441 GEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMV 496 GE+QAAL L GV QA V+ REDRPGD RLVGYI D +LR ALA +LP +MV Sbjct: 855 GEVQAALTALPGVRQAGVLIREDRPGDPRLVGYIVPAPGAEPDAGELRAALARTLPPHMV 914 Query: 497 PTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVG 556 P A+V L +PLT NGKLDR ALP P R+ + R P TP E+ L ++A VLGV V Sbjct: 915 PWALVPLPALPLTSNGKLDRAALPVPAARAGGSGQR-PVTPQEKTLCALFADVLGVTEVA 973 Query: 557 VDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFVEQTXXXXXXXXXXXXESHVV--- 612 DD FF+LGG S+ +++AR R G RD+F T H Sbjct: 974 TDDVFFELGGHSLNGTRLLARIRTEFGTDLTLRDLFAFPTVAGLLPLLDDNGRQHTTPPL 1033 Query: 613 ---DEGVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATL 669 E + A + +L +V+GP+ +N + + + V LQ + +RH L Sbjct: 1034 PPRPERLPLSHAQQRLWFLDQVEGPSPAYNIPTAVRLEGPLDIPALAVALQDVTNRHEPL 1093 Query: 670 RLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDV---LVEARNRLDPAAGAMVS 726 R + + E + +L PEA AR L D+ L EA R AG + Sbjct: 1094 RTLLAEDSEGPHQ-VILPPEA----ARPELTHSTVAPGDLAAALAEAARRPFDLAGEIPL 1148 Query: 727 AVWV----RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARW 782 + + L+L++HH A DG S +L+ DL A+ G + +A Sbjct: 1149 KAHLFGCGPDDHTLLLLVHHTAGDGASVEVLVRDLAHAYGARRAGDAPHFEPLPLQYADH 1208 Query: 783 SALLAEHAKTDTVRDLADAWR-AVTSVPQALPPVQPDTDTYVTA--GQLSASLDVETTRQ 839 + + D WR A+ +P+ L T V G+ A E T Sbjct: 1209 TLRRRHLLDDPSDSTQLDHWRDALAGLPEQLELPTDHTRPAVPTRRGEAIAFTVPEHTHH 1268 Query: 840 LLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVG 899 L + A V ++ A + D P+G V GR D+ D+ VG Sbjct: 1269 TLRAMAQAHGVTVFMVMQAALAALLSRHGAGHDIPLGTPVA--GRSDDGTEDL-----VG 1321 Query: 900 WFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVK 934 +F V L V+GD +V V+ Sbjct: 1322 FF---------VNTLVLRNDVSGDPTFAELVSRVR 1347 Score = 435 bits (1118), Expect = e-119 Identities = 347/1038 (33%), Positives = 481/1038 (46%), Gaps = 65/1038 (6%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDD--VYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 L +T QQ + A + DD +Y +++TG +D L AV + L Sbjct: 8 LGVTAAQQSVWL----AGQLADDHRLYHCAAYLSLTGSIDPRTLGTAVRRTLDETEALRT 63 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 RFV Q GE +Q+L D GD P+ A +A L T A Sbjct: 64 RFVPQDGELLQILEPGAGQLLLEADFSGDP-DPERAAHDWMHAALAAPVRLDRAGTATHA 122 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQE---IFAGYFGHRLPAAAPYRNFVNWLXXX 1267 L+ ++H +HHI +DG+ + L+ ++ P P+ L Sbjct: 123 LLTLGPSRHLLYFGYHHIALDGYGALLHLRRLAHVYTALSNGDDPGPCPFGPLAGVLTEE 182 Query: 1268 XXXXXXXXWREVLDG-FETPTLVAPPGVPGPRGIES----------YRVSAETTRALGEL 1316 R DG F T +L PG E+ +S E T L Sbjct: 183 AAYRDSDNHRR--DGEFWTRSLAGADEAPGLSEREAGALAVPLRRTVELSGERTEKLAAS 240 Query: 1317 ARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAG-AESMVGLLINTVPIR 1375 A + +++L AA + R D G V+ R L G A +L N VP+R Sbjct: 241 AAATGARWSSLLVAATAAFVRRHAAADDTVIGLPVTAR---LTGPALRTPCMLANDVPLR 297 Query: 1376 ---------AKVSADTT--VGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFL 1424 A + ADTT VG L R H E H L + +G ++ + Sbjct: 298 LDARLDAPFAALLADTTRAVGTLAR----HQRFRGEELHRNLGGVGRTAGLARVTVNVLA 353 Query: 1425 YESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRVEY--DTSVFDVSEI 1482 Y +D F G V E ++ + ++ PG G+++ + + +++ +++ Sbjct: 354 Y----VDNIRF-GDCRAVVHELSSGPVRDFHINSYGTPGTPDGVQLVFSGNPALYTATDL 408 Query: 1483 ETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFA 1542 +RF R L+A+ DP ++ R +L + + P ++PE+FA Sbjct: 409 ADHQERFLRFLDAVTADPDLPTGRHRLLSPGTRARLLDDSRGTERPVP---RATLPELFA 465 Query: 1543 RQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAI 1602 Q R P+APAV +G L Y +L + + A LA G VAL +P+SA+++ + Sbjct: 466 EQARRTPDAPAVQHDGTVLTYRDLHRSVERAAGRLAGLGLRTEDVVALALPKSAESVAIL 525 Query: 1603 LAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVD--DPA 1660 L + + GAAY+P+DP+ PA RL +L D +P VTTG + DG ++ D Sbjct: 526 LGIQRAGAAYVPLDPTHPAERLARVLDDTRPRYLVTTGHI----DGLSHPTPQLAAADLL 581 Query: 1661 VEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWS 1720 E P P+P + AY+I TSG+TG PKGV +TH + + GP A Sbjct: 582 REGGPEPAPGRPAPGNAAYIIQTSGSTGRPKGVVVTHEGLATLAADQIRRYRTGPDARVL 641 Query: 1721 QWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMM 1780 Q+ S FDV V E+ LL GG LVI P+ + G L L +E V TP A+ M Sbjct: 642 QFISPGFDVFVSELSMTLLSGGCLVIPPDGLTGR--HLADFLAAEAVTTTSLTPGALATM 699 Query: 1781 SPEGLEGT-ALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPI 1839 L L+V GE CP E+ D+W R ++NAYGPTE+T+ A VP+ Sbjct: 700 PATDLPHLRTLIVGGEVCPPEIFDQWGRGRDIVNAYGPTETTVEATAWHRDGATHGPVPL 759 Query: 1840 GSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGAR 1899 G P +VLD L PVP G GELYLA T RFVA PFG PG+R Sbjct: 760 GRPTLNRRGYVLDPALEPVPDGTTGELYLAGEGLARGYVAAPGPTAERFVADPFGPPGSR 819 Query: 1900 MYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRP 1959 MYRTGDLVR G L+++GRAD QVK+RG+RIELGE+QAAL+ + GV QA V+ REDRP Sbjct: 820 MYRTGDLVRRRSGGMLEFVGRADGQVKLRGFRIELGEVQAALTALPGVRQAGVLIREDRP 879 Query: 1960 GDKRLVGYITGT--ADPAAA--RSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPA 2015 GD RLVGYI A+P A R+ L LP +MVP A+V L LPLT NGKLDR ALP Sbjct: 880 GDPRLVGYIVPAPGAEPDAGELRAALARTLPPHMVPWALVPLPALPLTSNGKLDRAALPV 939 Query: 2016 PEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTAL 2075 P ++ + P T EKTL +FA VLGV R+ A + T Sbjct: 940 PAARAGGSGQRPVTPQEKTLCALFADVLGVTEVATDDVFFELGGHSLNGTRLLARIRTEF 999 Query: 2076 DADLSVRTLFEAPTVAKL 2093 DL++R LF PTVA L Sbjct: 1000 GTDLTLRDLFAFPTVAGL 1017 Score = 405 bits (1042), Expect = e-110 Identities = 305/823 (37%), Positives = 422/823 (51%), Gaps = 69/823 (8%) Query: 14 DLLDEDEHDQIEVWGNRA---VLTDPGP---TPVTIPALFAEQVVRAPDAVALVSGDRSW 67 D+L E + + WG A V PG + LF E+V PDAVA+ W Sbjct: 3044 DVLGAGERETLLGWGAGAEPGVRALPGAGAGAGAGLVGLFEERVRTDPDAVAVRGAGVEW 3103 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 +Y EL+ +N +A L G P V ++ R + + +L+V K+G YLPVDP P Sbjct: 3104 SYAELNARANAVARWLIGRGVGPERGVGVVMDRGPDVVAMLLAVAKSGGFYLPVDPQWPT 3163 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQY-DLAVIDMADPAIDRR--------PSDALSGP 178 RI ++++DA A+ +L + ++ D V+D A A + R D G Sbjct: 3164 ERIDWVLADAGIDLAVVGENLAAAVEAVRDCEVVDYAQIARETRLNEQAATDAGDVTDGE 3223 Query: 179 RPDDLA-----YMTYTSGTTGVPKAVAVTHHNVTQLVSA---LHADLPSGPGQVWSQWHS 230 R L Y+ YTSG+TG+PK V VTH +V + + G G V S S Sbjct: 3224 RVSALLSGHPLYVIYTSGSTGLPKGVVVTHASVGAYLRRGRNAYRGAADGLGHVHS---S 3280 Query: 231 LVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPS---AAGMLS 287 L FD++V ++ L+ GG + ++G D + L T L TPS G L Sbjct: 3281 LAFDLTVTVLFTPLVSGGCV-----TLGDLDDTANGLGAT----FLKATPSHLPLLGQLD 3331 Query: 288 PEGLESTTLIVAGEACPTELVDRWA---PGRVMINAYGPTEATIYAA---MSEPLXXXXX 341 TL++ GEA + W P +INAYGPTE T+ A + Sbjct: 3332 RVLAPDATLLLGGEALTAGALHHWRTHHPHTTVINAYGPTELTVNCAEYRIPPGHCLPDG 3391 Query: 342 XXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGE 401 LFVLD LR P +GELYVAG G+A GY+GRPDLTA RFVACPF Sbjct: 3392 PVPIGRPFTGHHLFVLDPALRLTPPDTIGELYVAGDGLARGYLGRPDLTAERFVACPFRS 3451 Query: 402 TGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAR 461 GERMYRTGDL RW SDG LE++GRAD+QVKIRG+RIELGE++AA+A V +A+ + R Sbjct: 3452 PGERMYRTGDLARWRSDGTLEFIGRADDQVKIRGFRIELGEVEAAVAAHPHVARAIAVVR 3511 Query: 462 EDRPGDKRLVGYITGTADPAQLRTALAES----LPAYMVPTAVVVLDTIPLTVNGKLDRR 517 EDRPGD+RLV Y+TG +DP+ L +A+ ++ LPAYMVP+AVVVLD IPLT NGK+DR Sbjct: 3512 EDRPGDQRLVAYVTG-SDPSGLSSAVTDTVAGRLPAYMVPSAVVVLDQIPLTPNGKVDRA 3570 Query: 518 ALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR 577 ALPAP S RAP T E+IL ++A VLG+++VGVD+ FFDLGG S+L+ ++ +R Sbjct: 3571 ALPAPGTASGTTS-RAPGTAREEILCTLFADVLGLDQVGVDEDFFDLGGHSLLATRLTSR 3629 Query: 578 ARAA-GIQCRPRDIFVEQTXXXXXXXXXXXXES----HVVDEGVG--PVVATPIMRW-LR 629 R+A GI R +F T S V E G P+ W L Sbjct: 3630 IRSALGIDLGVRALFKAPTVGRLDQLLQQQTTSLRAPLVARERTGCEPLSFAQQRLWFLH 3689 Query: 630 EVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDT-DEWSLLVP 688 +++GP +N + + + + L ++ RH +LR + Q+D+ W ++P Sbjct: 3690 QLEGPNAAYNIPMALRLTGRLDLTALEAALTDVIARHESLRTVI--AQDDSGGVWQNILP 3747 Query: 689 EAGAVGARECLRT--VDA--LTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIH 741 L T VDA L + V AR+ D + A R T L+L++H Sbjct: 3748 -TDDTRTHLTLDTMPVDAHTLQNRVDEAARHPFDLTTEIPLRATVFRVTDDEHVLLLVLH 3806 Query: 742 HLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSA 784 H+A DG S L DL+ A+ + +LPA +A ++A Sbjct: 3807 HIAGDGWSMAPLAHDLSAAYTVRLEHHAPQLPALAVQYADYAA 3849 Score = 386 bits (992), Expect = e-104 Identities = 247/615 (40%), Positives = 342/615 (55%), Gaps = 32/615 (5%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQI-EVWGNRAVLTDPGPTPVTIPALFAEQVVRA----P 55 + A+P T L + LL +DE D+I WG+ TP+ P AEQ+VR P Sbjct: 5178 LAADP-TAPLGTVPLLTDDERDRILGDWGSGT------HTPLP-PRSVAEQIVRRAALDP 5229 Query: 56 DAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTG 115 DAVA+++ + +YREL+ S A +LA+ G + VA +PR+ + ++L VL+TG Sbjct: 5230 DAVAVITAEEELSYRELERLSGETARLLADRGIGRESLVAVALPRTAGLVTTLLGVLRTG 5289 Query: 116 AAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQ--YDLAVIDMADPAIDRRPSD 173 AAYLP+D +P R+ ++SDA+P LT A L RL ++D P P+ Sbjct: 5290 AAYLPLDTGYPAERLAHVLSDARPDLVLTHAGLAGRLPAGLAPTVLVDEPQPPAAAAPAV 5349 Query: 174 ALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVF 233 S P D LAY+ +TSG+TG PK VA+ ++ ++ P ++ F Sbjct: 5350 PTS-PSGDHLAYVIHTSGSTGRPKGVAIAESSLRAFLADAVRRHDLTPHDRLLAVTTVGF 5408 Query: 234 DVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPS-------AAGML 286 D++ E++ LL G +V+ E P + +L V+V+ TPS A Sbjct: 5409 DIAGLELFAPLLAGAAIVLADEDAVRDPASITSLCARHHVTVVQATPSWWRAMLDGAPAD 5468 Query: 287 SPEGLESTTLIVAGEACPTELVD-RWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXX 345 + LE ++V GE P +L A G + N YGPTEATI+A + Sbjct: 5469 AAARLEHVRILVGGEPLPADLARVLTATGAAVTNVYGPTEATIWATAAPLTAGDDRTPGI 5528 Query: 346 XXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGER 405 + +LD L P P GV GE+++AG G+A GY+ RPDLTA RFVA PF GER Sbjct: 5529 GTPLDNWRVHILDAALGPVPPGVPGEIHIAGSGLARGYLRRPDLTAERFVANPFAP-GER 5587 Query: 406 MYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRP 465 MYRTGDL R+ DG LE+LGR D+QVK+RG+RIELG+++AALA+ V +A R D Sbjct: 5588 MYRTGDLGRFRPDGTLEHLGRVDDQVKVRGFRIELGDVEAALARHPDVGRAAAAVRPDHR 5647 Query: 466 GDKRLVGYI-----TGTADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALP 520 G RLV Y+ T D +LR + E LP YMVP+A V L T+P T NGKLDR ALP Sbjct: 5648 GQGRLVAYVVPRPGTRGPDAGELRETVRELLPDYMVPSAQVTLTTLPHTPNGKLDRAALP 5707 Query: 521 APEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA 580 AP + + A RAP+T E+ILA ++A +LG+ VG D FFDLGGDS+LS+Q+V+RAR Sbjct: 5708 APVFGTPAG--RAPATREEKILAGLFADILGLPDVGADSGFFDLGGDSVLSIQLVSRARR 5765 Query: 581 AGIQCRPRDIFVEQT 595 G+ RD+F T Sbjct: 5766 EGLHITVRDVFEHGT 5780 >tr|C1AUS0|C1AUS0_RHOOB Tax_Id=632772 SubName: Full=Putative non-ribosomal peptide synthetase;[Rhodococcus opacus] Length = 8906 Score = 1329 bits (3440), Expect = 0.0 Identities = 844/2196 (38%), Positives = 1183/2196 (53%), Gaps = 133/2196 (6%) Query: 14 DLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELD 73 D+LD E + + L +P T+ LFA R+ A A+V S TY ELD Sbjct: 5426 DILDRAERESV-----LPALAEPVGAHATLVELFARAAERSRGATAVVCEGVSLTYEELD 5480 Query: 74 EASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFM 133 +NRLA +L GA P VA RS + ++++L+V+K+GA Y+PVD +P R+ ++ Sbjct: 5481 TRANRLARLLIARGAGPETLVAVAAARSVDLVVALLAVVKSGAGYVPVDVTYPAERLAYV 5540 Query: 134 MSDAKPVAALTTADLRS--RLDQYDLAVIDMADPAIDRRPSDAL-------SGP-RPDDL 183 +DA+PV LTT R ++D + A + L +GP PD + Sbjct: 5541 FADARPVCVLTTVAESGAVRASGVPAVLVDGPETAEELGRVSPLPVTDRDRNGPLHPDSV 5600 Query: 184 AYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGA 243 AY+ YTSG+TG PK V V+H NV L + G VW+ +HS FD SVWE+WGA Sbjct: 5601 AYVIYTSGSTGQPKGVQVSHRNVATLFAHTQPLFRFGAADVWTMFHSAAFDFSVWELWGA 5660 Query: 244 LLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSP-----EGLESTTLIV 298 LLHGGRLVVV SPD LL E V+VL QTPSA L+ +G E +V Sbjct: 5661 LLHGGRLVVVDYFTTRSPDAFLRLLRGENVTVLNQTPSAFYQLAEADRVADGAELALRVV 5720 Query: 299 A--GEACPTELVDRWAPGR-----VMINAYGPTEATIYAA---MSEPLXXXXXXXXXXXX 348 GEA + RW ++N YG TE T++ + + L Sbjct: 5721 VFGGEALDLGQLTRWYTRHGDTVPALVNMYGITETTVHVSHLPLDGELAASASASVIGRA 5780 Query: 349 XXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYR 408 ++VLD L P P GVVGELYV+G V+ GY+GR LT++RFVA P+ G RMYR Sbjct: 5781 LPGLRVYVLDSRLHPVPPGVVGELYVSGAQVSRGYLGRFTLTSTRFVADPY-TPGARMYR 5839 Query: 409 TGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDK 468 +GDL RW + GQL+YLGR D QV+++G+RIELGE+++AL DGV Q+VV+AR +R Sbjct: 5840 SGDLGRWNAVGQLDYLGRNDFQVQVKGFRIELGEVESALLACDGVAQSVVLARNER---- 5895 Query: 469 RLVGYITGTAD----PAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEY 524 LVGY+ AD PA + + L A+MVP AVVVL+T+PLTVNGKLDRRALP P+Y Sbjct: 5896 -LVGYVVPEADRVLDPAGILDTVGGRLAAHMVPAAVVVLETLPLTVNGKLDRRALPEPDY 5954 Query: 525 RSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQ 584 + RAP+T E+ILA ++A+VLG++ VGVDDSFF +GGDSI+S+Q+V RA+A+G+ Sbjct: 5955 GRLVSPGRAPATETERILAGLFAEVLGLDTVGVDDSFFAVGGDSIMSIQLVTRAKASGVV 6014 Query: 585 CRPRDIFVEQTXXXXXXXXXXXXESHVVDE----GVGPVVATPIMRWLREVDGPTGQFNQ 640 PRD+F +T E+ ++E GVG TPI+RW+ +G +++Q Sbjct: 6015 ITPRDVFERKTVAALAEVATSGEETVTLEELPGGGVGEFPLTPIVRWMLGREGDFRRYSQ 6074 Query: 641 TVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLR 700 + PA + ED + +QA+LDRH LR R+ + W++ G V A E +R Sbjct: 6075 AALFTTPAELDEDTLTAAMQAVLDRHDVLRARLYRSDRAGHGWTMAAAPPGWVRATEVVR 6134 Query: 701 TVDALTDD--------VLVEARNRLDPAAGAMVSAVWVRETS------QLVLMIHHLAVD 746 TV D L A RLDP +G MV AVW + +L+++ HH+ VD Sbjct: 6135 TVPLAAADSFTGAASRELDAAAGRLDPESGVMVQAVWFASNAAPAAAGRLLIVAHHVVVD 6194 Query: 747 GVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVT 806 GVSWRIL+ DL +A A+ +G + LPA GTS W+ L + A+ + WR + Sbjct: 6195 GVSWRILVPDLALACARVLSGDAPALPATGTSMRTWAHALTDVAQEPSRTAELGLWRRML 6254 Query: 807 SVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA--- 863 P +P T + + L V T LL +P AF V D LL A LA Sbjct: 6255 GTPDPPLGSRPLTPADIQTSDVEVRLPVAVTETLLTSLPQAFHGNVADGLLTALALALVR 6314 Query: 864 WTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGD 923 W + V++EGHGR + + DL+RTVGWFTT +PV L ++ + E Sbjct: 6315 WRRDRGIESSAALVNLEGHGREEHVVPGADLARTVGWFTTIFPVGLDLDGVDVEDAFGAG 6374 Query: 924 AALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPEV--DLG-GSDPTIGFNYLGRLGAGAGE 979 A G VKAVKE+LRS+P+ G+ +GLLRYL+ + +L + P + FNYLGRLGAGA Sbjct: 6375 PAAGDAVKAVKERLRSIPDHGIGFGLLRYLDDDTARELSVPAGPQVSFNYLGRLGAGAAP 6434 Query: 980 LSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQ 1039 + + D +P V++NA T DT GP L A+W++ E Sbjct: 6435 GGDWMPVSDAGLAAAAHSG----LPAAAVVDVNARTTDTAAGPVLTATWSFPVGVIAAED 6490 Query: 1040 ATRLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYD-VTDVLPLTPV 1098 L+RLW AL + H R GGGG TPSD+ L Q ID+L RY +TDV PL+P+ Sbjct: 6491 VGELARLWVRALEALSEHARSGGGGFTPSDLGLVSLGQGAIDDLEHRYPAMTDVWPLSPL 6550 Query: 1099 QQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFV-EQFG 1157 Q G+LFH+ A D Y VQL + + G +D R+R A ++ RHPNL + F + G Sbjct: 6551 QAGMLFHAELA-DESVDAYLVQLILDLGGDVDAARVRRAAGALLDRHPNLRSAFCHDADG 6609 Query: 1158 EPVQVLTADPMIAWRYLDLRG-DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSG 1216 VQV++ + WR +DL D + EIE+L AA+R+ D+ P R L+ TSG Sbjct: 6610 GAVQVVSGRVTVPWREIDLSALDGSAAEAEIERLLAADRTTPFDMATAPLIRFLLVWTSG 6669 Query: 1217 NQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP----YRNFVNWLXXXXXXXX 1272 + R V T HHI++DGWS+P++++E+ Y P+ P YR+++ W+ Sbjct: 6670 GRCRLVSTNHHILLDGWSMPLMIRELLTLYATDADPSPLPRVRDYRDYLAWMRGRDTGLS 6729 Query: 1273 XXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAE--------TTRALGELARSQHTTI 1324 W + LDG E PTL+ +P R + VS E T L E AR++ T+ Sbjct: 6730 ARAWADALDGVEEPTLL----IPADRARQLSTVSREWVFDLDRDRTDRLREAARTRGLTL 6785 Query: 1325 NTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTV 1384 N++LQ W +L +TG+ DV FG VSGRP +LAG E+MVGL INTVP+R + D T+ Sbjct: 6786 NSILQTVWGIVLGLLTGRDDVVFGATVSGRPPELAGIETMVGLFINTVPVRVTLRPDETL 6845 Query: 1385 GDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAF---MGVQEL 1441 G LL ++Q+ L+H + L +I +G FDTL ++ESYP+D + + L Sbjct: 6846 GALLERVQAEQAAMLDHHYTGLAEIRDAAGPGAGFDTLTVFESYPVDRAGLSEDTDIAGL 6905 Query: 1442 AVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMI--DD 1499 VT + R+ HYPLS++A L L+ EY + + + DR R+L+A D Sbjct: 6906 RVTGVDARDAAHYPLSLVASAAESLHLKFEYVPDLLAQGTVGDIADRVVRVLDACAGPDV 6965 Query: 1500 PARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGE 1559 P RLS ++ D ER +L V P S +++ ++F DP+A A++ Sbjct: 6966 PLARLS---LLTDRERGEL-----VPVRGGPAASVRTLAQIFTDAATVDPDAVALSSGDV 7017 Query: 1560 SLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSV 1619 ++Y ELDE + +LA L G P SVA+ +PRS ++++ + AV K GA ++P+DP+ Sbjct: 7018 EVSYRELDERSTRLARALIGRGLGPEISVAVGIPRSIESVLCVWAVAKAGAVFVPVDPNY 7077 Query: 1620 PAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDP----------AVEIYPSTTL 1669 P R+ ML D++ +TT D +R G + + + +DDP A + + Sbjct: 7078 PDERIAHMLTDSECALGLTTSDHLARLAG-NTRWLVLDDPVFAAECAAGSAAPVDDADRT 7136 Query: 1670 LTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDV 1729 + D Y++YTSG+TG+PKGV +TH + A A P + + + FD Sbjct: 7137 APVTLDSAVYVVYTSGSTGMPKGVTVTHRGLDNFAADQLARFGADPESRTLHFSTPSFDG 7196 Query: 1730 SVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTA 1789 SV+E A +VI P ++ G DDL L+ V + T +A+ + P GL+ A Sbjct: 7197 SVFEYLQAFGAAATMVIAPPTVFGG-DDLAQLIRDRRVTHAFVTTAALASLDPAGLDAFA 7255 Query: 1790 -LVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGAT 1848 +VV GEACP +V RWA R + N YGPTE+T+ + IS PL+PG + + IG P+ Sbjct: 7256 DVVVGGEACPPGLVSRWAPGRRLYNGYGPTETTVMSNISDPLTPG-ERITIGGPIRGVTE 7314 Query: 1849 FVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVR 1908 VL+ L+PVP GV GELYLA LT TRFVA P PG RMYRTGD+VR Sbjct: 7315 LVLNSRLQPVPAGVPGELYLAGAGLARGYHRRPGLTATRFVADPC-RPGERMYRTGDVVR 7373 Query: 1909 WGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYI 1968 W ++YLGR+D QVK+RG+RIELGEI A L+ GV A +A GD L Y+ Sbjct: 7374 WTAGHTIEYLGRSDFQVKVRGFRIELGEIDATLAADPGVRFAATVAYRGPAGDTLLASYV 7433 Query: 1969 T----GTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ-SAQR 2023 T D L +RLPA+MVP+++ L+ +PL GK DR+AL PE+ A Sbjct: 7434 VPAPGHTLDTGDLTRGLASRLPAHMVPSSITVLDEIPLNAVGKFDRKALLTPEFDVGAGE 7493 Query: 2024 YRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRT 2083 YRAP ++T+A +FA VLG++R A R A + AL D+ VRT Sbjct: 7494 YRAPADPVQETVADVFAEVLGLDRVSADAGFFDLGGNSLSATRAVARLRAALGTDIGVRT 7553 Query: 2084 LFEAPTVAKLSLHVEH-----------DAGERTDRV 2108 LFEAPTV L+ +EH AG R DR+ Sbjct: 7554 LFEAPTVETLAARLEHAGAGPSGRPALTAGARPDRI 7589 Score = 1315 bits (3402), Expect = 0.0 Identities = 849/2178 (38%), Positives = 1154/2178 (52%), Gaps = 127/2178 (5%) Query: 24 IEVWGN--RAVLTD----PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASN 77 I+V G RA LT PG T+P L + DA ALVS R +YR+LDE S+ Sbjct: 2840 IDVLGTAERAALTPVSGGPGVPARTLPQLLSAAAAVDSDAAALVSDGRRISYRDLDERSD 2899 Query: 78 RLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDA 137 RLA +L G P VA +PRS E++L++ SV K GAA+LPVDP HP RI +M+ D+ Sbjct: 2900 RLARLLIGRGIGPEQVVALAMPRSIESVLAVWSVAKAGAAFLPVDPNHPAERIEYMLGDS 2959 Query: 138 KPVAALTTADLRSRLDQYDLAVIDMAD----------PAIDRRPSDALSGPRPDDLAYMT 187 V LTTA +RS L + + + D PA +D S D AY+ Sbjct: 2960 GAVVGLTTAAVRSALPA-PIPWLVLGDARTDAELSLFPATAVTDADRSSTLHVDHPAYVI 3018 Query: 188 YTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHG 247 YTSG+TG PK V TH + + + + S FD SV E+ A+ G Sbjct: 3019 YTSGSTGRPKGVVTTHRGLANFAATEQDTFGTTAASRTLHFASPSFDASVLELMLAVGPG 3078 Query: 248 GRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG-EACPTE 306 +V+ SV DDL +LL E+V+ TP+A + P GLE +V G EACP E Sbjct: 3079 ATMVIASPSVYGG-DDLADLLRRERVTHCFVTPAALASVDPAGLERVRCVVTGGEACPPE 3137 Query: 307 LVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPE 366 LV RWAPGR M +AYGPTE+T+ +++S PL VLD L P P Sbjct: 3138 LVARWAPGRNMFDAYGPTESTVVSSISAPLAPGEPVTIGAPALGFTET-VLDGRLHPVPA 3196 Query: 367 GVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGR 426 GV GELY+AG +A GY GR LTA RFVA PFG G RMYRTGDLVRW +DGQL+YLGR Sbjct: 3197 GVAGELYLAGPALARGYSGRHALTAERFVANPFGPPGGRMYRTGDLVRWTADGQLDYLGR 3256 Query: 427 ADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQ 482 D QVKIRG+RIELGE+++AL + V AV R D +RL+GY+ + DP + Sbjct: 3257 TDFQVKIRGFRIELGEVESALLAHENVAAAVADVRRDGHSGRRLIGYVVPETGASVDPGE 3316 Query: 483 LRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQIL 542 + L +YMVP AV+V+ +P+TV+GK+DR+ALP P++ D R+PST E +L Sbjct: 3317 VLQFAGTRLASYMVPAAVLVIAALPVTVHGKIDRKALPEPDFGVGVTDSRSPSTETEALL 3376 Query: 543 ADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXX 602 A ++ VLG+ VGVDDSFF LGGDSI+S+Q+VARA+AAG+ PRD+F ++ Sbjct: 3377 AGLFRDVLGLASVGVDDSFFALGGDSIMSIQLVARAKAAGLILSPRDVFERRSVAGLAEV 3436 Query: 603 XXXXXESHVVDE-----GVGPVVATPIMRW-LREVDGPTGQFNQTVITQAPAGVTEDDVV 656 VV E GVGPV TP++ W L G +F+Q+V AP G+T +D+ Sbjct: 3437 AHHERADAVVLEELPGGGVGPVPLTPVVAWMLDRSGGRLERFSQSVPVTAPRGLTREDLA 3496 Query: 657 VILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVD----------ALT 706 + A+LDRH LR R+ ++T W++ V G+V A +R V A+ Sbjct: 3497 AAVDAVLDRHDMLRARL--AADETGRWAMTVLPPGSVWADALIRHVPVTSFEAGDFAAVA 3554 Query: 707 DDVLVEARNRLDPAAGAMVSAVWV---RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQ 763 L A +RLDPA+ +M+ +W +L+ + HHL VDGVSWRIL+ DL A + Sbjct: 3555 RAELNAAADRLDPASASMLQVLWFDGPDGQGRLLPVAHHLVVDGVSWRILIADLAAAHTR 3614 Query: 764 HCTGQSIELPAGGTSFARWSALLAEHAKTDTVRDL---ADAWRAVTSVPQAL---PPVQP 817 G S LPA GTS RWS H TD R W+++ P L P+ P Sbjct: 3615 VAEGLSAALPAVGTSMRRWS-----HGLTDAARSRHAEGALWQSILDGPDPLLGSRPLDP 3669 Query: 818 DTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA---WTEFLNRSDTP 874 D G++ + T LL +PAAF V D LL A LA W Sbjct: 3670 AVDVEAATGRVVVEVPTGVTDALLTTLPAAFHGAVGDGLLTALALAMIRWRRQRGAGTAD 3729 Query: 875 IGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVK 934 + V++EGHGR D + DLSRTVGWFTT +PV L + + + +AG A G +KAVK Sbjct: 3730 VLVNLEGHGREDHVVPGADLSRTVGWFTTLFPVRLDLTGIDVDAALAGTDAAGAAIKAVK 3789 Query: 935 EQLRSLPE-GLTYGLLRYLNPEVDLG---GSDPTIGFNYLGRLGAGAGELSEELWRIDQX 990 EQL ++P+ G+ YG+LRYL+P P + FNYLGR+ AG++ W + Sbjct: 3790 EQLLAVPDHGIGYGMLRYLDPGDSAALRRFRPPQVSFNYLGRVATSAGDVP---W-LPVA 3845 Query: 991 XXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEA 1050 MP V++NA T D P L A+W++ E LS LW A Sbjct: 3846 DSGDLGGTQNHDMPAAWVVDVNAATTVRDGEPVLTATWSYPTGVLAAEDVDELSALWVRA 3905 Query: 1051 LAGICAHV-RGGGGGLTPSDVAPARLTQRQIDELSQRY-DVTDVLPLTPVQQGLLFHSTF 1108 L + H G GGLTPSD+ + Q ID L + Y D+ D+ PL+P+Q GLLFH+ Sbjct: 3906 LTALAEHAGLPGAGGLTPSDLDLVSVGQADIDRLGRTYPDLADIWPLSPLQAGLLFHAQL 3965 Query: 1109 ARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPM 1168 + D Y VQL + + G +D RLR A ++ RH NL F + PVQV+ + Sbjct: 3966 S-AHRLDAYQVQLVLDLRGTVDPARLRHAAQGLLDRHANLRVAFADTGNGPVQVVRDSVI 4024 Query: 1169 IAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHI 1228 W +D+ P AA+R+ ++ E P R L+RT+ ++ R VLT HHI Sbjct: 4025 APWAEVDV------PPLGDTAFLAADRAVPFEMSEAPLLRFTLLRTAPDRFRLVLTHHHI 4078 Query: 1229 VIDGWSLPILLQEIFAGYFGH----RLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFE 1284 ++DGWS P++++++ Y LP PYR+++ W+ W L G + Sbjct: 4079 LLDGWSTPLVIKDLLVLYATDGDPTALPRVTPYRDYLQWIGRQDHERSTAAWVSALAGAD 4138 Query: 1285 TPTLVAPPGVPGPRGIESY--------RVSAETTRALGELARSQHTTINTVLQAAWTQLL 1336 PT VA P G +S+ V E TRAL LAR + T+NT++Q AW +L Sbjct: 4139 EPTFVA----PAAHGEQSFAEPEDVRLEVGEEKTRALEALARERGLTMNTLVQVAWGLVL 4194 Query: 1337 MRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHN 1396 + + DV FG VSGRP +AG ESMVGL INTVP+R ++ + T+ +LL++ Q + Sbjct: 4195 TTLGSREDVTFGATVSGRPPAVAGVESMVGLFINTVPVRLRLRREETLAELLQRFQREQS 4254 Query: 1397 DTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQE------LAVTEFNNRE 1450 L+H +L L +I G FDTL ++ESYP+D MG+ E + V + Sbjct: 4255 ALLDHHYLGLTEIQRAVGEAAAFDTLTVFESYPVDR---MGLSEDTDIGGMHVAGIEGID 4311 Query: 1451 YNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVV 1510 HYP ++MA L LR+ Y +VF E++ R R+++ ++ D L+ + ++ Sbjct: 4312 STHYPFTLMAHVDTALHLRLRYQPNVFGSEFAESVAARVARVVQILLSDIDTPLAHLTLL 4371 Query: 1511 DDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAA 1570 D E + AV P P+++PE+ P+A A F+G +Y ELD + Sbjct: 4372 SDAELREF-----TAVCGAPAGPPRTLPEILTVSAGHRPDASAFVFDGHETSYRELDARS 4426 Query: 1571 NQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGD 1630 + LA +L GA P VAL +PRS +++ A+ AV KTGAA++P+DP+ PA R+E ML D Sbjct: 4427 SALARVLIERGAGPETFVALGLPRSPESVPAVWAVAKTGAAFVPVDPTYPADRIENMLAD 4486 Query: 1631 AKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVE---IYPSTTLLTP-------SPDDIAYM 1680 + VTT R R G + + +DDP E S+ +T D AY Sbjct: 4487 SGAALGVTTSAHRHRLPG-SVPWLVLDDPDFERTWSAASSARVTDLDRRSVLDVDHAAYA 4545 Query: 1681 IYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLH 1740 IYTSG+TG PKGV +TH + +L P + S FDV+V E+ + Sbjct: 4546 IYTSGSTGRPKGVVVTHRGLANLLTEQTEHYVVSPDSRCLHICSPSFDVAVLELVQSCAA 4605 Query: 1741 GGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG-TALVVAGEACPT 1799 G LVI P + G +L ALL E V TP+ + + +G+E ALVVAG+A Sbjct: 4606 GATLVIAPPDVYGGA-ELSALLRRERVTHACITPAVLATVERDGVEHLEALVVAGDAVGD 4664 Query: 1800 EVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVP 1859 E+V W DR M N YGPTE+T+ S P+ PG + V IGSPV A VLD L+PVP Sbjct: 4665 ELVATWGADRPMFNGYGPTEATVLTTFSTPMEPG-EPVTIGSPVRGIALSVLDARLQPVP 4723 Query: 1860 PGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLG 1919 GV GELY+A LT RFVA P+G RMYRTGD+VRW D L+YLG Sbjct: 4724 AGVPGELYIAGTALARGYHRRPALTAERFVANPYGR--GRMYRTGDVVRWRRDHTLEYLG 4781 Query: 1920 RADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARS 1979 R+D QVKIRG R+ELGEI + L+ +D A + R GD LV Y+ A Sbjct: 4782 RSDFQVKIRGQRVELGEIDSVLTTHPHLDFAATLGRPGPLGDTALVSYVLPHDGEEVAAP 4841 Query: 1980 ELT----NRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQ-RYRAPETETEKT 2034 ++ LP YMVPAAVV L+ +PLT GKLDR+ALPAPE+ SA YRAP T E+ Sbjct: 4842 DVLAFAGRILPKYMVPAAVVVLDEIPLTPVGKLDRKALPAPEFISATLGYRAPTTPVEEA 4901 Query: 2035 LAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +A +FA VLG R A R A +N+ALDA + V LF+AP VA L+ Sbjct: 4902 VAQVFADVLGAPRVGADDSFFDLGGDSLSATRAVARINSALDAGIGVAALFDAPVVADLA 4961 Query: 2095 LHVEHDAGERTDRVSFAA 2112 + ++ A T + AA Sbjct: 4962 VRIDSAASTTTPSPAPAA 4979 Score = 510 bits (1314), Expect = e-141 Identities = 389/1131 (34%), Positives = 552/1131 (48%), Gaps = 119/1131 (10%) Query: 1054 ICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTDVLPLTPVQQGLLFHSTFARGIG 1113 + AHVR G L D P QR QR +PL+ QQ + F + F Sbjct: 1292 LAAHVRRAGTELV--DRPPLTAGQRP-----QR------VPLSLAQQRMWFINQF--DTS 1336 Query: 1114 DDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRY 1173 Y + + + + G LD LR AV V+ RH +L R+ P QV+ + Sbjct: 1337 SVAYNIPMAVRLIGPLDADTLRAAVADVIERHESLRTRYPASVDGPYQVVVDAADVV--- 1393 Query: 1174 LDLRGDDLTP----DHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIV 1229 DLTP D + A + D+ + RAAL+ T ++H V+ HHI Sbjct: 1394 -----PDLTPQVDGDESLHDRIATLLAGGFDVSAKVPLRAALLWTGPDEHVLVIVVHHIA 1448 Query: 1230 IDGWSLPILLQEIFAGYFGHR---LPAAAP----YRNFVNWLXXXXXXXXXXX------- 1275 DG SL L +++ Y R LP+ P Y +F W Sbjct: 1449 ADGASLAPLARDLIVAYSARRSGSLPSWEPLPVQYADFSVWQRRLLGSADDPDSLMSRQL 1508 Query: 1276 --WREVLDGFETPTLVAPP---GVPGPRGIE----SYRVSAETTRALGELARSQHTTINT 1326 WR L E P + A P P R + ++ + A R L LAR + T+ Sbjct: 1509 QYWRGALA--ELPEVSALPLDRNRPVTRSLAGATAAFPIDAGLHRQLLLLAREHNATLFM 1566 Query: 1327 VLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGD 1386 V+ AA LL RMTG DVA GT ++GR A + +VG+ +NT+ +R V + D Sbjct: 1567 VMHAALAVLLSRMTGSGDVAVGTPIAGRGE--AALDDLVGMFVNTLVLRTPVGSGDVFTD 1624 Query: 1387 LLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQLFDTLFLYESYPIDTSAFMGVQE 1440 +L + + H + + + H LF L +++ A + + Sbjct: 1625 VLARARDTDLGAFGHTDVPFESVVDELAPGRSTSHSPLFQVLLEFQN---TVRAHLELPG 1681 Query: 1441 LAVTEFN-NREYNHYPLSVMALPGHE-------LGLRVEYDTSVFDVSEIETLIDRFQRL 1492 L V + + + L + H+ + Y T VFD + ++ +RF R+ Sbjct: 1682 LTVEAVDVDPGVAKFDLQLSLAEHHDENGAAAGMSAAFLYATDVFDRTSVDGFGERFVRV 1741 Query: 1493 LEAMIDDPARRLSSMDVVDDDERTQ-LDEWANRAVLTQPVDSPQSIPEVFARQVERDPEA 1551 L A++DDP + + V+ ER LD W V T +++ E+FAR P+A Sbjct: 1742 LRAVVDDPVAVVGDIPVLGAAERDLVLDRWNREGVTT----GARTVVELFARVAAGTPDA 1797 Query: 1552 PAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAA 1611 AV E+L YG+LDE AN+LA LL G VA++V R+ D +V +LAVL G Sbjct: 1798 VAVVCGEETLTYGQLDEQANRLARLLIGEGVGTESLVAVLVDRTPDLVVTLLAVLAAGGG 1857 Query: 1612 YLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPAVE--------- 1662 Y+P+D S PA R+ M DA+PV AV + D + L VV +DDPA + Sbjct: 1858 YVPVDTSYPAERVAAMFDDARPVCAVVSADFAASAPA-GLPVVVIDDPATDRAVAGLSGL 1916 Query: 1663 -IYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQ 1721 + + L D +AY+I+TSG+TG PKGV ++H V +L VW+ Sbjct: 1917 PVTDADRLRPLRADAVAYVIFTSGSTGRPKGVQVSHRCVVTLLANTRDLFGFDSSDVWTL 1976 Query: 1722 WHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS 1781 +HS FD SVWE+WGAL+ GGRLV+V A SPD LL E V VL QTP+A ++ Sbjct: 1977 FHSYAFDFSVWELWGALVSGGRLVLVDYFTARSPDTFLELLRRERVTVLNQTPTAFYQLT 2036 Query: 1782 P--------EGLEGTAL-----VVAGEACPTEVVDRWAV-----DRVMINAYGPTESTIY 1823 E + T L + GEA ++RW D V++N YG TE+T++ Sbjct: 2037 EADRAASTVEDDDATPLSLRHVIFGGEALDVGQLERWYTRHDDRDPVLVNMYGITETTVH 2096 Query: 1824 AAISAPLSPGSDVVP---IGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXX 1880 + A + VP IG +P +VLD L PVPPGVVGELY++ Sbjct: 2097 VSFLALDRALAASVPGSVIGGGLPGLRVYVLDGRLHPVPPGVVGELYVSGDQVSRGYIGR 2156 Query: 1881 XXLTGTRFVACPFGE--PGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQ 1938 LT TRFVA PF GARMYR+GD+V+WG DG+L+Y+GR+D QV++RG+R+ELGE++ Sbjct: 2157 QGLTATRFVADPFDHRRAGARMYRSGDVVKWGADGRLEYVGRSDFQVQLRGFRVELGEVE 2216 Query: 1939 AALSDVDGVDQAVVIAR-EDRPGDKRLVGYITGTA----DPAAARSELTNRLPAYMVPAA 1993 AAL+ GV Q+VV+ R +DR GD RLVGY+ A D AA + +P+YMVPAA Sbjct: 2217 AALAACAGVAQSVVVVRGDDRDGD-RLVGYVVPEAGADVDAAAVLDAVGASVPSYMVPAA 2275 Query: 1994 VVTLETLPLTVNGKLDRRALPAPEYQSAQ-RYRAPETETEKTLAGIFAHVLGVERXXXXX 2052 VV ++ LPLTVNGKLDR++LP ++ +A + AP E+ +A +FA +LG+ R Sbjct: 2276 VVVIDALPLTVNGKLDRKSLPEADFGTATVGFVAPRNPVEEIVAAVFADLLGIVRVGAND 2335 Query: 2053 XXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 A R+ A VN A+ L VR +F+APTVA L+ E AGE Sbjct: 2336 SFFALGGNSLTATRLVARVNAAVGDCLGVRDVFDAPTVAGLAARAE--AGE 2384 Score = 500 bits (1287), Expect = e-138 Identities = 373/1081 (34%), Positives = 526/1081 (48%), Gaps = 111/1081 (10%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D +PL+ QQ + F + F Y + + + + G LD+ LR AV VV R +L Sbjct: 4984 DRIPLSMAQQRMWFVNQF--DTSSPAYNIPIALRLIGALDRAALRAAVGDVVERQESLRT 5041 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAA 1210 F P QV+ D A LD ++ D + A D+ + FRA Sbjct: 5042 VFPGSVDGPHQVIV-DAGRATPGLD--PVPVSGDRALRDAVATLVGTGFDVSDEIPFRAR 5098 Query: 1211 LIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNFVNW 1263 L QH + HHI DG+S+ L +++ Y + P Y ++ W Sbjct: 5099 LFELEPEQHVLAIVVHHIAADGFSMMPLARDVMLAYTARTVGETPGWTPLPVQYADYSIW 5158 Query: 1264 LXXXXXXXXXXX---------WREVLDGFETPTLVAPPGVPGPRGIE-SYR-------VS 1306 W + L G P ++ P V PR + SYR V Sbjct: 5159 QRDVLGAVDEPDSVMSTQLGYWTDTLSG--APEVLQIP-VDRPRPAQRSYRGDVVEFDVP 5215 Query: 1307 AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVG 1366 A R+L +A ++T+ + AA+ LL R++G D+ GT V+GR A + +VG Sbjct: 5216 ARLHRSLNRIAAEHNSTLFMAVHAAFAVLLSRLSGTGDITLGTPVAGR--GHAVLDDVVG 5273 Query: 1367 LLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQLFD 1420 + +NT+ +R V + G +L +++ EH + + + H LF Sbjct: 5274 MFVNTLVLRTVVDPRASFGAVLSAVRAADLGAFEHADIPFERLVDHLAPERSTSHAPLFQ 5333 Query: 1421 TLFLY---------------ESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHE 1465 L + +S +D EL++ E + + A G Sbjct: 5334 VLIEFRNAEGTHLELPGLTVDSLDVDVGVAKFDLELSLAERVDDD--------GAPAGLA 5385 Query: 1466 LGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRA 1525 GLR + T V D + +RF R+LE++ A + +D++D ER + Sbjct: 5386 AGLR--FATDVLDRDTVTRFAERFLRVLESIAAAEALPVGDIDILDRAERESV-----LP 5438 Query: 1526 VLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPG 1585 L +PV + ++ E+FAR ER A AV EG SL Y ELD AN+LA LL GA P Sbjct: 5439 ALAEPVGAHATLVELFARAAERSRGATAVVCEGVSLTYEELDTRANRLARLLIARGAGPE 5498 Query: 1586 KSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTT----GD 1641 VA+ RS D +VA+LAV+K+GA Y+P+D + PA RL ++ DA+PV +TT G Sbjct: 5499 TLVAVAAARSVDLVVALLAVVKSGAGYVPVDVTYPAERLAYVFADARPVCVLTTVAESGA 5558 Query: 1642 LRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPS--------PDDIAYMIYTSGTTGVPKGV 1693 +R+ G +V+ + A E+ + L PD +AY+IYTSG+TG PKGV Sbjct: 5559 VRA--SGVPAVLVDGPETAEELGRVSPLPVTDRDRNGPLHPDSVAYVIYTSGSTGQPKGV 5616 Query: 1694 AITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAG 1753 ++H NV + G VW+ +HS FD SVWE+WGALLHGGRLV+V Sbjct: 5617 QVSHRNVATLFAHTQPLFRFGAADVWTMFHSAAFDFSVWELWGALLHGGRLVVVDYFTTR 5676 Query: 1754 SPDDLHALLVSEGVNVLYQTPSAV-------RMMSPEGLEGTALVVAGEACPTEVVDRWA 1806 SPD LL E V VL QTPSA R+ L +V GEA + RW Sbjct: 5677 SPDAFLRLLRGENVTVLNQTPSAFYQLAEADRVADGAELALRVVVFGGEALDLGQLTRWY 5736 Query: 1807 VDR-----VMINAYGPTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPV 1858 ++N YG TE+T++ + + L+ + IG +P +VLD L PV Sbjct: 5737 TRHGDTVPALVNMYGITETTVHVSHLPLDGELAASASASVIGRALPGLRVYVLDSRLHPV 5796 Query: 1859 PPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYL 1918 PPGVVGELY++ LT TRFVA P+ PGARMYR+GDL RW GQL YL Sbjct: 5797 PPGVVGELYVSGAQVSRGYLGRFTLTSTRFVADPY-TPGARMYRSGDLGRWNAVGQLDYL 5855 Query: 1919 GRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTA----DP 1974 GR D QV+++G+RIELGE+++AL DGV Q+VV+AR ++RLVGY+ A DP Sbjct: 5856 GRNDFQVQVKGFRIELGEVESALLACDGVAQSVVLAR-----NERLVGYVVPEADRVLDP 5910 Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEK 2033 A + RL A+MVPAAVV LETLPLTVNGKLDRRALP P+Y + RAP TETE+ Sbjct: 5911 AGILDTVGGRLAAHMVPAAVVVLETLPLTVNGKLDRRALPEPDYGRLVSPGRAPATETER 5970 Query: 2034 TLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKL 2093 LAG+FA VLG++ ++++ A ++ R +FE TVA L Sbjct: 5971 ILAGLFAEVLGLDTVGVDDSFFAVGGDSIMSIQLVTRAK-ASGVVITPRDVFERKTVAAL 6029 Query: 2094 S 2094 + Sbjct: 6030 A 6030 Score = 492 bits (1267), Expect = e-136 Identities = 360/1070 (33%), Positives = 514/1070 (48%), Gaps = 79/1070 (7%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D +PL+ QQ + F + F Y + + + +TG LD LR AV VV RH +L Sbjct: 7587 DRIPLSYAQQRMWFINQF--DTSSPAYNIPMVVRLTGDLDVDALRLAVTDVVTRHESLRT 7644 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDL-LERPTFRA 1209 RF + GEPVQ + P DD E+ +L +A + L F Sbjct: 7645 RFPLRDGEPVQEILP-PGAPMPPPTAVADDSRLRDELTRLVSAGFDVAAAVPLRIALFTL 7703 Query: 1210 ALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFVN 1262 + H + HHI DG+S+ L++++ Y R PA P Y ++ Sbjct: 7704 DTVSLDTGTHVLAVVVHHISADGFSMAPLVRDVMVAYESRVHGRAPAWTPLPVQYADYTL 7763 Query: 1263 WLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIE-SYRVSAE 1308 W W L G E PT P G + + A Sbjct: 7764 WQRRLLGSEDDPGSLISGQLAYWEAALAGLPELLELPTDRRRPAQQSFHGDRVRFTIDAG 7823 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLL 1368 + AR +T ++ AA LL R+ G DVA GT ++GR A + +VG+ Sbjct: 7824 LHERIRAAAREHRSTEFMIVHAALAVLLGRLGGTGDVAIGTPIAGRGE--AALDDLVGMF 7881 Query: 1369 INTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG------HEQLFDTL 1422 + T+ +R + A DLL Q++ H L + G H LF Sbjct: 7882 VGTLALRTTIEAGQPFRDLLAQVRDADLGAFAHADLPFERVVDAVGPVRSTAHSPLFQVS 7941 Query: 1423 FLYESYPIDTSAFMGVQ------ELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSV 1476 +++ G+ +LAV + + P G ++Y T + Sbjct: 7942 LEFQNTENPALRLPGLSVEGLDPDLAVVKVDLEVILDERFDTDGTPAGMTGA-IDYATDL 8000 Query: 1477 FDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQS 1536 FD + +RF R+L+++ +P + ++++ DE A LT +P + Sbjct: 8001 FDADTVLGFAERFVRILDSVTAEPGIPVGDIEILGTDEV---------AALTPARGAPDA 8051 Query: 1537 ----IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMV 1592 +P++ V DP+A A+++ G ++ Y ELDE +N+LA L GA PG +VAL + Sbjct: 8052 PTLLLPDLLTAAVRLDPDADALSYRGRAITYRELDETSNRLARRLIEAGAGPGTTVALSL 8111 Query: 1593 PRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQ 1652 RS ++++++ AV +TGAA+LP+DP P R+E ML D+ V+ VT + R R Sbjct: 8112 SRSIESVLSVWAVARTGAAFLPVDPGYPLDRIEHMLTDSGAVSGVTVREHRDRLPAAVTW 8171 Query: 1653 VVEVDDPAVEIYPSTTLLTPSPDDI--------------AYMIYTSGTTGVPKGVAITHG 1698 +V +DD + + T SP + AY+IYTSG+TGVPKGVA+TH Sbjct: 8172 IV-LDDAR----DADRIRTRSPGPVTDADRTAPLHEFHPAYLIYTSGSTGVPKGVAVTHR 8226 Query: 1699 NVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDL 1758 + + L + + S FD SV+E+ A G LVI P +I G + L Sbjct: 8227 GLANLAAEERERLAVTRDSRVLHFASPSFDASVFELVMAFCAGAALVIAPRTIYGGTE-L 8285 Query: 1759 HALLVSEGVNVLYQTPSAVRMMSPEGLEGT-ALVVAGEACPTEVVDRWAVDRVMINAYGP 1817 ALL E V+ + TP+A+ M P G E LVVAGEACP E+V RWA R M NAYGP Sbjct: 8286 AALLSEERVSHGFVTPTAMASMDPLGFESLRTLVVAGEACPPELVARWAPGRRMFNAYGP 8345 Query: 1818 TESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXX 1877 TE+TI + IS L PG D + +G+P A VLD LRPVP GV GELY++ Sbjct: 8346 TETTIMSNISDALVPG-DPISLGAPTRGVAEVVLDSRLRPVPVGVAGELYVSGRALASGY 8404 Query: 1878 XXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEI 1937 LT +RFVA P+G PG RMYRTGD+VRW DG L+Y+GR+D Q+KIRG+RIE GEI Sbjct: 8405 HRRCGLTASRFVAAPWGAPGDRMYRTGDVVRWRRDGTLEYVGRSDFQMKIRGFRIEPGEI 8464 Query: 1938 QAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELT----NRLPAYMVPAA 1993 AAL+ GV AV I R G+ LV Y+ ELT RLP++MVPAA Sbjct: 8465 DAALTAHPGVGFAVTIGRAGPAGEPLLVSYVRPVGGAYVDTGELTRLVAERLPSHMVPAA 8524 Query: 1994 VVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXX 2053 VV L+ +PLT GKLDR ALPAPE+ S R+RAP T+ E + +FA VLG++R Sbjct: 8525 VVVLDQIPLTPVGKLDRAALPAPEFLSGTRFRAPATDLEAAVVDVFAEVLGLDRVGADDN 8584 Query: 2054 XXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGE 2103 A + AA+ LD + ++ +F PT + L+ + + E Sbjct: 8585 FFERSGNSLLATKAVAALQDRLDRKIPLQWMFLDPTPSGLARRIALPSAE 8634 Score = 483 bits (1243), Expect = e-133 Identities = 369/1103 (33%), Positives = 531/1103 (48%), Gaps = 110/1103 (9%) Query: 1088 DVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPN 1147 D + +P++ QQ + F + F Y V + + +TG LD L+ AV VV RH + Sbjct: 2397 DPSREVPVSLAQQRMWFINQF--DTVSAAYNVAIALRLTGTLDVAALQAAVTDVVERHES 2454 Query: 1148 LAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTP--------DHEIEQLCAAERSAVC 1199 L F P QV+ +A DLTP D E+++L SA Sbjct: 2455 LRTVFPLTDSGPRQVILPPETVA--------PDLTPHPVPQAAVDAELDRLL----SAGF 2502 Query: 1200 DLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRN 1259 D+ RA L +H + HHI DG+S+ L +++ + Y RL AAP Sbjct: 2503 DVTAEAPLRARLFAAGEQEHVLAVVVHHIAADGFSMVPLARDVLSAYTA-RLHGAAP--- 2558 Query: 1260 FVNWLXXXXXXXXXXXW-REVLD-------------GFETPTLVAPPGV---------PG 1296 +W W R+ L G+ T TL P V P Sbjct: 2559 --DWTPLPVQYADYTLWQRDRLGDEDDENSPLARQLGYWTATLADLPDVLELPTDRPRPA 2616 Query: 1297 PRGIESYRVS----AETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVS 1352 R + + RV A+ + + ++AR +T+ L AA LL R++ D+A GT ++ Sbjct: 2617 TRTLGAGRVEFGIGADLHQGVVQVARRHGSTVFMALHAALAVLLSRLSASDDIAVGTPIA 2676 Query: 1353 GRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI--- 1409 GR A + +VG+ +NT+ +R V T +LL Q++ H + + Sbjct: 2677 GRGE--AELDDLVGMFVNTLVLRTHVDGARTFAELLAQVRGADLGAFTHADVPFERVVER 2734 Query: 1410 ---HHVSGHEQLFDTLFLYES-------------YPIDTSAFMGVQELAVTEFNNREYNH 1453 + + LF + +++ P+D + +L ++ N + + Sbjct: 2735 LRPSRSTEYSPLFQVMLEFQNTERPELELPGLHVEPLDLAFDTINFDLQLSLRENVDADG 2794 Query: 1454 YPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDD 1513 P + A G Y T +FD + +R R+L A+ D P + +DV+ Sbjct: 2795 RPAGISAALG--------YATDIFDEHTVAAFAERLVRILGAVTDSPDAPVGDIDVLGTA 2846 Query: 1514 ERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQL 1573 ER L V P +++P++ + D +A A+ +G ++Y +LDE +++L Sbjct: 2847 ERAAL-----TPVSGGPGVPARTLPQLLSAAAAVDSDAAALVSDGRRISYRDLDERSDRL 2901 Query: 1574 ANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKP 1633 A LL G P + VAL +PRS ++++A+ +V K GAA+LP+DP+ PA R+E+MLGD+ Sbjct: 2902 ARLLIGRGIGPEQVVALAMPRSIESVLAVWSVAKAGAAFLPVDPNHPAERIEYMLGDSGA 2961 Query: 1634 VAAVTTGDLRSRFDGFDLQVVEVD---DPAVEIYPSTTLL------TPSPDDIAYMIYTS 1684 V +TT +RS +V D D + ++P+T + T D AY+IYTS Sbjct: 2962 VVGLTTAAVRSALPAPIPWLVLGDARTDAELSLFPATAVTDADRSSTLHVDHPAYVIYTS 3021 Query: 1685 GTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRL 1744 G+TG PKGV TH + T + + S FD SV E+ A+ G + Sbjct: 3022 GSTGRPKGVVTTHRGLANFAATEQDTFGTTAASRTLHFASPSFDASVLELMLAVGPGATM 3081 Query: 1745 VIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVV-AGEACPTEVVD 1803 VI S+ G DDL LL E V + TP+A+ + P GLE VV GEACP E+V Sbjct: 3082 VIASPSVYGG-DDLADLLRRERVTHCFVTPAALASVDPAGLERVRCVVTGGEACPPELVA 3140 Query: 1804 RWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVV 1863 RWA R M +AYGPTEST+ ++ISAPL+PG + V IG+P VLD L PVP GV Sbjct: 3141 RWAPGRNMFDAYGPTESTVVSSISAPLAPG-EPVTIGAPALGFTETVLDGRLHPVPAGVA 3199 Query: 1864 GELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADE 1923 GELYLA LT RFVA PFG PG RMYRTGDLVRW DGQL YLGR D Sbjct: 3200 GELYLAGPALARGYSGRHALTAERFVANPFGPPGGRMYRTGDLVRWTADGQLDYLGRTDF 3259 Query: 1924 QVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARS 1979 QVKIRG+RIELGE+++AL + V AV R D +RL+GY+ + DP Sbjct: 3260 QVKIRGFRIELGEVESALLAHENVAAAVADVRRDGHSGRRLIGYVVPETGASVDPGEVLQ 3319 Query: 1980 ELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGI 2038 RL +YMVPAAV+ + LP+TV+GK+DR+ALP P++ R+P TETE LAG+ Sbjct: 3320 FAGTRLASYMVPAAVLVIAALPVTVHGKIDRKALPEPDFGVGVTDSRSPSTETEALLAGL 3379 Query: 2039 FAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVE 2098 F VLG+ ++++ A A LS R +FE +VA L+ Sbjct: 3380 FRDVLGLASVGVDDSFFALGGDSIMSIQLVARAKAA-GLILSPRDVFERRSVAGLAEVAH 3438 Query: 2099 HDAGERTDRVSFAAVHGSDVTEV 2121 H ER D V + G V V Sbjct: 3439 H---ERADAVVLEELPGGGVGPV 3458 Score = 438 bits (1126), Expect = e-120 Identities = 327/952 (34%), Positives = 474/952 (49%), Gaps = 103/952 (10%) Query: 24 IEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVL 83 ++ W V T T+ LFA PDAVA+V G+ + TY +LDE +NRLA +L Sbjct: 1768 LDRWNREGVTTGAR----TVVELFARVAAGTPDAVAVVCGEETLTYGQLDEQANRLARLL 1823 Query: 84 AEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAAL 143 G + VA L+ R+ + ++++L+VL G Y+PVD ++P R+ M DA+PV A+ Sbjct: 1824 IGEGVGTESLVAVLVDRTPDLVVTLLAVLAAGGGYVPVDTSYPAERVAAMFDDARPVCAV 1883 Query: 144 TTADLRSRLDQYDLAVIDMADPAIDRR----------PSDALSGPRPDDLAYMTYTSGTT 193 +AD + L V+ + DPA DR +D L R D +AY+ +TSG+T Sbjct: 1884 VSADFAASAPA-GLPVVVIDDPATDRAVAGLSGLPVTDADRLRPLRADAVAYVIFTSGST 1942 Query: 194 GVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVV 253 G PK V V+H V L++ VW+ +HS FD SVWE+WGAL+ GGRLV+V Sbjct: 1943 GRPKGVQVSHRCVVTLLANTRDLFGFDSSDVWTLFHSYAFDFSVWELWGALVSGGRLVLV 2002 Query: 254 PESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTL-------------IVAG 300 SPD LL E+V+VL QTP+A L+ ++T+ I G Sbjct: 2003 DYFTARSPDTFLELLRRERVTVLNQTPTAFYQLTEADRAASTVEDDDATPLSLRHVIFGG 2062 Query: 301 EACPTELVDRWAPGR-----VMINAYGPTEATIYA---AMSEPLXXXXXXXXXXXXXXXX 352 EA ++RW V++N YG TE T++ A+ L Sbjct: 2063 EALDVGQLERWYTRHDDRDPVLVNMYGITETTVHVSFLALDRALAASVPGSVIGGGLPGL 2122 Query: 353 XLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGE--TGERMYRTG 410 ++VLD L P P GVVGELYV+G V+ GYIGR LTA+RFVA PF G RMYR+G Sbjct: 2123 RVYVLDGRLHPVPPGVVGELYVSGDQVSRGYIGRQGLTATRFVADPFDHRRAGARMYRSG 2182 Query: 411 DLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAR-EDRPGDKR 469 D+V+WG+DG+LEY+GR+D QV++RG+R+ELGE++AALA GV Q+VV+ R +DR GD R Sbjct: 2183 DVVKWGADGRLEYVGRSDFQVQLRGFRVELGEVEAALAACAGVAQSVVVVRGDDRDGD-R 2241 Query: 470 LVGYITGTA----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 LVGY+ A D A + A+ S+P+YMVP AVVV+D +PLTVNGKLDR++LP ++ Sbjct: 2242 LVGYVVPEAGADVDAAAVLDAVGASVPSYMVPAAVVVIDALPLTVNGKLDRKSLPEADFG 2301 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQC 585 +A + AP P E+I+A V+A +LG+ RVG +DSFF LGG+S+ + ++VAR AA C Sbjct: 2302 TATVGFVAPRNPVEEIVAAVFADLLGIVRVGANDSFFALGGNSLTATRLVARVNAAVGDC 2361 Query: 586 -RPRDIFVEQT---XXXXXXXXXXXXESHVVDEGVGPVVATPI------MRWLREVDGPT 635 RD+F T +S P P+ M ++ + D + Sbjct: 2362 LGVRDVFDAPTVAGLAARAEAGESRAQSRPAPAPRDPSREVPVSLAQQRMWFINQFDTVS 2421 Query: 636 GQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGA 695 +N + + + + + +++RH +LR V + +L PE A Sbjct: 2422 AAYNVAIALRLTGTLDVAALQAAVTDVVERHESLR-TVFPLTDSGPRQVILPPETVAPDL 2480 Query: 696 RE---CLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVS 749 VDA D +L D A A + A Q L +++HH+A DG S Sbjct: 2481 TPHPVPQAAVDAELDRLLSAG---FDVTAEAPLRARLFAAGEQEHVLAVVVHHIAADGFS 2537 Query: 750 WRILLEDLNIAWAQHCTGQSIE---LPAGGTSFARW-----------SALLAEHAK--TD 793 L D+ A+ G + + LP + W ++ LA T Sbjct: 2538 MVPLARDVLSAYTARLHGAAPDWTPLPVQYADYTLWQRDRLGDEDDENSPLARQLGYWTA 2597 Query: 794 TVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQ 853 T+ DL D T P +P T T + AG++ + + + G V A R G Sbjct: 2598 TLADLPDVLELPTDRP------RPATRT-LGAGRVEFGIGADLHQ---GVVQVARRHG-- 2645 Query: 854 DILLVAFGLAWTEFLNR----SDTPIGVDVEGHGRYDELASDVDLSRTVGWF 901 + +A A L+R D +G + G G + +L VG F Sbjct: 2646 STVFMALHAALAVLLSRLSASDDIAVGTPIAGRG-------EAELDDLVGMF 2690 Score = 431 bits (1107), Expect = e-117 Identities = 315/867 (36%), Positives = 434/867 (50%), Gaps = 64/867 (7%) Query: 1276 WREVLDGFETPTLVAPPGV---PGPRGIESYRVSAETT----RALGELARSQHTTINTVL 1328 WR L+G P L+ P P ES RV+ R + LA T TV Sbjct: 479 WRRRLEGL--PELLPLPTDRRRPATLSPESDRVTVVVPTRLHRRVAALAGDTGTAGRTVF 536 Query: 1329 QAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLL 1388 A + LL R+TG D+A GTAV VG +TV +R++ + DT+ D L Sbjct: 537 LTALSILLGRVTGSGDIAVGTAVE------------VGDRTDTVVVRSRYAGDTSCRDYL 584 Query: 1389 RQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELAV--TEF 1446 ++ + + H + + + G + + E+Y + + EF Sbjct: 585 AHVRDVAAEAVSHTGVPFDRLVQELG-------VSVSEAYAPIVQVLLDTRPPGSPGAEF 637 Query: 1447 NNREYNHYPLSVMALPGHELGLRVEYD--TSVFDVSEIETLIDRFQRLLEAMIDDPARRL 1504 + G G VE+ +FD + +R+ R+L+AM P + Sbjct: 638 PGLDLCVSVTEASGESGQPAGATVEFGFAADLFDARTVRVAAERYLRILDAMTAGPDVPV 697 Query: 1505 SSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYG 1564 ++++ DER+ L V P S +++P++FA DP A A+T +GE L+Y Sbjct: 698 GDIEILSADERSALTP-----VRGLPARSERTLPDLFADAAALDPAATALTRQGEQLSYR 752 Query: 1565 ELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARL 1624 ELD + Q+A +L G P VAL +PRS ++ ++ AV KTGAA++P+DP+ PA R+ Sbjct: 753 ELDRWSTQVARILIEKGVGPESFVALALPRSFRSVASVWAVAKTGAAFVPVDPNYPADRV 812 Query: 1625 EFMLGDAKPVAAVTTGDLRSRF-DGFDLQVVEVDDPAVEIY-----PSTTLLTPSP---D 1675 ++ML D+ V +T +R R D V++ D E P T P D Sbjct: 813 DYMLADSGVVLGLTEQSVRGRLHDSIPWCVLDDPDFRAECAARPDDPPTDADRTRPLHLD 872 Query: 1676 DIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWS----QWHSLVFDVSV 1731 + AY+IYTSG+TG PKGV +TH + LD A+ GA S + + FD SV Sbjct: 873 NAAYLIYTSGSTGQPKGVTVTH----RGLDNFAADQQERFGATRSSRTLHFSTPSFDASV 928 Query: 1732 WEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL-EGTAL 1790 +E A G +V+VP + G +L LL SE V + T +A+ + P+ L + + Sbjct: 929 FEYLQAFGVGATMVVVPPTAYGG-SELADLLRSERVTHGFVTTAALGTIPPDSLGDFLDV 987 Query: 1791 VVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFV 1850 V GEACP ++V RWA DR + +AYGPTE+TI A ISAP++ G D + +G P+ V Sbjct: 988 AVGGEACPPDLVARWAPDRRLYDAYGPTETTIMANISAPMTAG-DPITLGGPIRGAEEVV 1046 Query: 1851 LDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWG 1910 LD L PVP GV GELY+A LT RFVA P+G R+YRTGD+VRW Sbjct: 1047 LDARLHPVPVGVPGELYIAGCGVARGYHRRPGLTAARFVADPYGR--GRLYRTGDVVRWR 1104 Query: 1911 DDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITG 1970 D L+YL R+D QVK+RG+RIELGEI A L V AV I R GD LV Y+ Sbjct: 1105 PDHTLEYLRRSDFQVKVRGFRIELGEIDAVLQTHPDVRLAVTIGRPGPSGDTVLVSYVVP 1164 Query: 1971 TADPAAARSEL----TNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS-AQRYR 2025 A SEL NRLPAYMVP+ VV L+ +PL GKLDR ALP P + S A ++ Sbjct: 1165 AAGRPIETSELLRQVRNRLPAYMVPSVVVVLDEIPLNPVGKLDRAALPEPRFLSAAAEFK 1224 Query: 2026 APETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLF 2085 AP E+++A +F VLGVER A RV A VN AL +D+ VR LF Sbjct: 1225 APADPVEESIAEVFTEVLGVERISVDDSFFDLGGNSLVATRVIARVNAALGSDVGVRALF 1284 Query: 2086 EAPTVAKLSLHVEHDAGERTDRVSFAA 2112 EAPTV L+ HV E DR A Sbjct: 1285 EAPTVELLAAHVRRAGTELVDRPPLTA 1311 Score = 423 bits (1088), Expect = e-115 Identities = 262/555 (47%), Positives = 329/555 (59%), Gaps = 17/555 (3%) Query: 36 PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA 95 P + +P L V PDA AL R+ TYRELDE SNRLA L E GA PG TVA Sbjct: 8049 PDAPTLLLPDLLTAAVRLDPDADALSYRGRAITYRELDETSNRLARRLIEAGAGPGTTVA 8108 Query: 96 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQ- 154 + RS E++LS+ +V +TGAA+LPVDP +P RI M++D+ V+ +T + R RL Sbjct: 8109 LSLSRSIESVLSVWAVARTGAAFLPVDPGYPLDRIEHMLTDSGAVSGVTVREHRDRLPAA 8168 Query: 155 YDLAVIDMA---DPAIDRRPSDALSGPRPDDL-----AYMTYTSGTTGVPKAVAVTHHNV 206 V+D A D R P R L AY+ YTSG+TGVPK VAVTH + Sbjct: 8169 VTWIVLDDARDADRIRTRSPGPVTDADRTAPLHEFHPAYLIYTSGSTGVPKGVAVTHRGL 8228 Query: 207 TQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHN 266 L + L + S FD SV+E+ A G LV+ P ++ + L Sbjct: 8229 ANLAAEERERLAVTRDSRVLHFASPSFDASVFELVMAFCAGAALVIAPRTIYGGTE-LAA 8287 Query: 267 LLITEKVSVLCQTPSAAGMLSPEGLEST-TLIVAGEACPTELVDRWAPGRVMINAYGPTE 325 LL E+VS TP+A + P G ES TL+VAGEACP ELV RWAPGR M NAYGPTE Sbjct: 8288 LLSEERVSHGFVTPTAMASMDPLGFESLRTLVVAGEACPPELVARWAPGRRMFNAYGPTE 8347 Query: 326 ATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIG 385 TI + +S+ L + VLD LRP P GV GELYV+G +A+GY Sbjct: 8348 TTIMSNISDALVPGDPISLGAPTRGVAEV-VLDSRLRPVPVGVAGELYVSGRALASGYHR 8406 Query: 386 RPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQA 445 R LTASRFVA P+G G+RMYRTGD+VRW DG LEY+GR+D Q+KIRG+RIE GEI A Sbjct: 8407 RCGLTASRFVAAPWGAPGDRMYRTGDVVRWRRDGTLEYVGRSDFQMKIRGFRIEPGEIDA 8466 Query: 446 ALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRTALAESLPAYMVPTAVV 501 AL GV AV I R G+ LV Y+ D +L +AE LP++MVP AVV Sbjct: 8467 ALTAHPGVGFAVTIGRAGPAGEPLLVSYVRPVGGAYVDTGELTRLVAERLPSHMVPAAVV 8526 Query: 502 VLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSF 561 VLD IPLT GKLDR ALPAPE+ S +RAP+T E + DV+A+VLG++RVG DD+F Sbjct: 8527 VLDQIPLTPVGKLDRAALPAPEFLSGTR-FRAPATDLEAAVVDVFAEVLGLDRVGADDNF 8585 Query: 562 FDLGGDSILSMQVVA 576 F+ G+S+L+ + VA Sbjct: 8586 FERSGNSLLATKAVA 8600 Score = 420 bits (1079), Expect = e-114 Identities = 320/912 (35%), Positives = 459/912 (50%), Gaps = 53/912 (5%) Query: 36 PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA 95 P + T+P LFA+ P A AL +YRELD S ++A +L E G P + VA Sbjct: 718 PARSERTLPDLFADAAALDPAATALTRQGEQLSYRELDRWSTQVARILIEKGVGPESFVA 777 Query: 96 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRL-DQ 154 +PRS ++ S+ +V KTGAA++PVDP +P R+ +M++D+ V LT +R RL D Sbjct: 778 LALPRSFRSVASVWAVAKTGAAFVPVDPNYPADRVDYMLADSGVVLGLTEQSVRGRLHDS 837 Query: 155 YDLAVIDMAD------PAIDRRPSDALSGPRP---DDLAYMTYTSGTTGVPKAVAVTHHN 205 V+D D D P+DA RP D+ AY+ YTSG+TG PK V VTH Sbjct: 838 IPWCVLDDPDFRAECAARPDDPPTDA-DRTRPLHLDNAAYLIYTSGSTGQPKGVTVTHRG 896 Query: 206 VTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLH 265 + + + + + FD SV+E A G +VVVP + +L Sbjct: 897 LDNFAADQQERFGATRSSRTLHFSTPSFDASVFEYLQAFGVGATMVVVPPTAYGG-SELA 955 Query: 266 NLLITEKVSVLCQTPSAAGMLSPEGL-ESTTLIVAGEACPTELVDRWAPGRVMINAYGPT 324 +LL +E+V+ T +A G + P+ L + + V GEACP +LV RWAP R + +AYGPT Sbjct: 956 DLLRSERVTHGFVTTAALGTIPPDSLGDFLDVAVGGEACPPDLVARWAPDRRLYDAYGPT 1015 Query: 325 EATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYI 384 E TI A +S P+ + VLD L P P GV GELY+AG GVA GY Sbjct: 1016 ETTIMANISAPMTAGDPITLGGPIRGAEEV-VLDARLHPVPVGVPGELYIAGCGVARGYH 1074 Query: 385 GRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQ 444 RP LTA+RFVA P+G R+YRTGD+VRW D LEYL R+D QVK+RG+RIELGEI Sbjct: 1075 RRPGLTAARFVADPYGRG--RLYRTGDVVRWRPDHTLEYLRRSDFQVKVRGFRIELGEID 1132 Query: 445 AALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAQLRTALAESLPAYMVPTAV 500 A L V AV I R GD LV Y+ A + ++L + LPAYMVP+ V Sbjct: 1133 AVLQTHPDVRLAVTIGRPGPSGDTVLVSYVVPAAGRPIETSELLRQVRNRLPAYMVPSVV 1192 Query: 501 VVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDS 560 VVLD IPL GKLDR ALP P + SAA +++AP+ P E+ +A+V+ +VLGVER+ VDDS Sbjct: 1193 VVLDEIPLNPVGKLDRAALPEPRFLSAAAEFKAPADPVEESIAEVFTEVLGVERISVDDS 1252 Query: 561 FFDLGGDSILSMQVVARARAA-GIQCRPRDIF----VEQTXXXXXXXXXXXXESHVVDEG 615 FFDLGG+S+++ +V+AR AA G R +F VE + + G Sbjct: 1253 FFDLGGNSLVATRVIARVNAALGSDVGVRALFEAPTVELLAAHVRRAGTELVDRPPLTAG 1312 Query: 616 VGP-----VVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLR 670 P +A M ++ + D + +N + + + D + + +++RH +LR Sbjct: 1313 QRPQRVPLSLAQQRMWFINQFDTSSVAYNIPMAVRLIGPLDADTLRAAVADVIERHESLR 1372 Query: 671 LRVEDTQEDTDEWSLLVPEAGAVGARECLRTVD---ALTDDVLVEARNRLDPAAGAMVSA 727 R + + + ++V A V + VD +L D + D +A + A Sbjct: 1373 TRYPASVD--GPYQVVVDAADVV--PDLTPQVDGDESLHDRIATLLAGGFDVSAKVPLRA 1428 Query: 728 --VWV-RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFAR 781 +W + LV+++HH+A DG S L DL +A++ +G LP F+ Sbjct: 1429 ALLWTGPDEHVLVIVVHHIAADGASLAPLARDLIVAYSARRSGSLPSWEPLPVQYADFSV 1488 Query: 782 WS-ALLAEHAKTDTVRD-LADAWR-AVTSVPQ--ALPPVQPDTDTYVTAGQLSA-SLDVE 835 W LL D++ WR A+ +P+ ALP + T AG +A +D Sbjct: 1489 WQRRLLGSADDPDSLMSRQLQYWRGALAELPEVSALPLDRNRPVTRSLAGATAAFPIDAG 1548 Query: 836 TTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLS 895 RQLL + A + ++ A + + D +G + G G E A D + Sbjct: 1549 LHRQLL-LLAREHNATLFMVMHAALAVLLSRMTGSGDVAVGTPIAGRG---EAALDDLVG 1604 Query: 896 RTVGWFTTKYPV 907 V + PV Sbjct: 1605 MFVNTLVLRTPV 1616 Score = 416 bits (1068), Expect = e-113 Identities = 285/807 (35%), Positives = 406/807 (50%), Gaps = 46/807 (5%) Query: 15 LLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDE 74 L D + + + V G P + T+ +F + PDAVAL SGD +YRELDE Sbjct: 6973 LTDRERGELVPVRGG------PAASVRTLAQIFTDAATVDPDAVALSSGDVEVSYRELDE 7026 Query: 75 ASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMM 134 S RLA L G P +VA IPRS E++L + +V K GA ++PVDP +PD RI M+ Sbjct: 7027 RSTRLARALIGRGLGPEISVAVGIPRSIESVLCVWAVAKAGAVFVPVDPNYPDERIAHML 7086 Query: 135 SDAKPVAALTTADLRSRL---------DQYDLAVIDMADPAIDRRPSDALSGPRPDDLAY 185 +D++ LTT+D +RL D A A A +D + D Y Sbjct: 7087 TDSECALGLTTSDHLARLAGNTRWLVLDDPVFAAECAAGSAAPVDDADRTAPVTLDSAVY 7146 Query: 186 MTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALL 245 + YTSG+TG+PK V VTH + + A + P + + FD SV+E A Sbjct: 7147 VVYTSGSTGMPKGVTVTHRGLDNFAADQLARFGADPESRTLHFSTPSFDGSVFEYLQAFG 7206 Query: 246 HGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLES-TTLIVAGEACP 304 +V+ P +V DDL L+ +V+ T +A L P GL++ ++V GEACP Sbjct: 7207 AAATMVIAPPTVFGG-DDLAQLIRDRRVTHAFVTTAALASLDPAGLDAFADVVVGGEACP 7265 Query: 305 TELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPA 364 LV RWAPGR + N YGPTE T+ + +S+PL L VL+ L+P Sbjct: 7266 PGLVSRWAPGRRLYNGYGPTETTVMSNISDPLTPGERITIGGPIRGVTEL-VLNSRLQPV 7324 Query: 365 PEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYL 424 P GV GELY+AG G+A GY RP LTA+RFVA P GERMYRTGD+VRW + +EYL Sbjct: 7325 PAGVPGELYLAGAGLARGYHRRPGLTATRFVADPC-RPGERMYRTGDVVRWTAGHTIEYL 7383 Query: 425 GRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITG----TADP 480 GR+D QVK+RG+RIELGEI A LA GV A +A GD L Y+ T D Sbjct: 7384 GRSDFQVKVRGFRIELGEIDATLAADPGVRFAATVAYRGPAGDTLLASYVVPAPGHTLDT 7443 Query: 481 AQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQ 540 L LA LPA+MVP+++ VLD IPL GK DR+AL PE+ A +YRAP+ P ++ Sbjct: 7444 GDLTRGLASRLPAHMVPSSITVLDEIPLNAVGKFDRKALLTPEFDVGAGEYRAPADPVQE 7503 Query: 541 ILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIF----VEQT 595 +ADV+A+VLG++RV D FFDLGG+S+ + + VAR RAA G R +F VE Sbjct: 7504 TVADVFAEVLGLDRVSADAGFFDLGGNSLSATRAVARLRAALGTDIGVRTLFEAPTVETL 7563 Query: 596 XXXXXXXXXXXXESHVVDEGVGP-----VVATPIMRWLREVDGPTGQFNQTVITQAPAGV 650 + G P A M ++ + D + +N ++ + + Sbjct: 7564 AARLEHAGAGPSGRPALTAGARPDRIPLSYAQQRMWFINQFDTSSPAYNIPMVVRLTGDL 7623 Query: 651 TEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDVL 710 D + + + ++ RH +LR R D + ++P + + L D++ Sbjct: 7624 DVDALRLAVTDVVTRHESLRTRFP--LRDGEPVQEILPPGAPMPPPTAVADDSRLRDELT 7681 Query: 711 VEARNRLDPAAGAMVS-AVWVRETSQL-------VLMIHHLAVDGVSWRILLEDLNIAWA 762 D AA + A++ +T L +++HH++ DG S L+ D+ +A+ Sbjct: 7682 RLVSAGFDVAAAVPLRIALFTLDTVSLDTGTHVLAVVVHHISADGFSMAPLVRDVMVAYE 7741 Query: 763 QHCTGQS---IELPAGGTSFARWSALL 786 G++ LP + W L Sbjct: 7742 SRVHGRAPAWTPLPVQYADYTLWQRRL 7768 Score = 60.8 bits (146), Expect = 3e-06 Identities = 68/304 (22%), Positives = 111/304 (36%), Gaps = 20/304 (6%) Query: 1123 ITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDLRGDDLT 1182 + +G LD LR + + + G P+Q + + Y+D R D Sbjct: 67 VEFSGALDMDLLRQETVEAAREFESPFLKVYDVDGRPLQYVDHRTDTSIAYVDFR-TDAD 125 Query: 1183 PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEI 1242 P + + DL ++++T + HH+ +DG+ +L+ I Sbjct: 126 PAAAAHEWMERDYVTPIDLSVDRLVETSILQTGDTHFLWYSRIHHVALDGYGAMTMLRRI 185 Query: 1243 FAGYFGHRLPAAAPYRNFV-----------NWLXXXXXXXXXXXWREVLDGFETPTLVAP 1291 A + ++ P N + W + G E TL Sbjct: 186 -AHRYSAKVAGREPDPNRAVSLRQLYDIDRRYRASDRFLTDREYWAGRVAGVEGTTLART 244 Query: 1292 PG-VPGPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTA 1350 G V +ES +S + L R TI AA L R TG+ +V Sbjct: 245 AGHVSAASTVESAVLSDDVVAVLDSRDRPSAATII----AAAACYLARRTGRTEVLVTIP 300 Query: 1351 VSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIH 1410 VS R A + G+L+N P+ +V A+ TV DL+ Q+Q L H+ +L+DI Sbjct: 301 VSARTT--AVLRNSGGMLVNVAPMPVRVRAEDTVADLIEQVQRELVAALRHQRCSLDDIR 358 Query: 1411 HVSG 1414 +G Sbjct: 359 RDAG 362 >tr|Q0SKF9|Q0SKF9_RHOSR Tax_Id=101510 SubName: Full=Non-ribosomal peptide synthetase; EC=5.1.1.3; EC=6.2.1.3;[Rhodococcus sp.] Length = 8928 Score = 1329 bits (3439), Expect = 0.0 Identities = 834/2160 (38%), Positives = 1160/2160 (53%), Gaps = 130/2160 (6%) Query: 42 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRS 101 T+ FA+ V R PDA A+ S D + TY ELD SNRLA +L G P VA +PR+ Sbjct: 5469 TLADRFAQSVARFPDATAVTSEDVALTYAELDARSNRLARLLISQGVGPETLVAVALPRT 5528 Query: 102 GEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVID 161 + I+++L+V+KTG YLPVD +P R+ F+ DA P +TT S L + I Sbjct: 5529 CDLIIALLAVIKTGGGYLPVDITYPADRLAFVFEDAAPNCVITTTGDVSALPDSETPAIL 5588 Query: 162 MADPAI-----DRRPSDALSGPRPDDL-----AYMTYTSGTTGVPKAVAVTHHNVTQLVS 211 + DP + P+ R L AY+ YTSG+TG PK V V+H NV L + Sbjct: 5589 LDDPETTADLAQQSPATITDADRVTPLDSSSVAYVIYTSGSTGRPKGVVVSHRNVLTLFA 5648 Query: 212 ALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITE 271 VW+ +HS FD SVWE+WG LL+GGRLVVV SP+ H LL E Sbjct: 5649 NTQPLYGFDENDVWTMFHSYAFDFSVWELWGPLLYGGRLVVVDYYTARSPEMFHELLRNE 5708 Query: 272 KVSVLCQTPSAAGMLSPE------------GLESTTLIVAGEACPTELVDRW-------A 312 +V+VL QTP+A L+ L +I GEA + RW A Sbjct: 5709 QVTVLNQTPTAFYQLAETDRIVSEIDVNAAALALRYVIFGGEALDLGQLGRWYSRHDDSA 5768 Query: 313 PGRVMINAYGPTEATI---YAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVV 369 P ++N YG TE T+ Y A+ + VLD+ L P P G + Sbjct: 5769 P--TLVNMYGITETTVHVSYLALDREFAESASASVIGRGIAGLHVHVLDRRLHPVPPGTI 5826 Query: 370 GELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADE 429 GE+YV+G V GY+GR L++SRFVA P G RMYRTGDL RW +DGQLEYLGR+D Sbjct: 5827 GEMYVSGDQVTRGYLGRAGLSSSRFVADPL-RPGARMYRTGDLARWNTDGQLEYLGRSDF 5885 Query: 430 QVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQLRT 485 QVKIRG+RIELGEI++AL + G+ QAVV+ R+D G RL+GY+ T + + Sbjct: 5886 QVKIRGFRIELGEIESALLRYRGIAQAVVLTRDDGHGGHRLIGYVVPESGATVEVSSALE 5945 Query: 486 ALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADV 545 + L +YMVP +VVLD +PLT NGKLDRRALP P++ + + RAP+T E +LA + Sbjct: 5946 FVGTQLTSYMVPATLVVLDALPLTSNGKLDRRALPEPDFGARVSAGRAPATEMETVLAGL 6005 Query: 546 YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXX 605 +A+VLG+E VGVDDSFF LGGDSI+S+Q+VARA+AAG+ PRD+F +T Sbjct: 6006 FAEVLGLESVGVDDSFFALGGDSIMSIQLVARAKAAGVVLTPRDVFEAKTVAALAEAASW 6065 Query: 606 XXESHVV--DE----GVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVIL 659 + VV DE G+G + TPI WL E G ++ QT + PA E + + Sbjct: 6066 AGAADVVVLDELPGGGIGEMPVTPITAWLLERGGDFRRYTQTALLSLPAAADETLLKRTI 6125 Query: 660 QALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA----------LTDDV 709 A++D H LR R+ + +W + V G V + L V+ + Sbjct: 6126 AAVVDHHDMLRARLLGAE---PQWRIEVQAVGVVDVDDVLHRVEVASVVGSGFAEVATRE 6182 Query: 710 LVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGVSWRILLEDLNIAWAQHCT 766 L A RLDP AG M+ VW Q L+++ HHL VDGVSWRIL+ DL AWAQ Sbjct: 6183 LDAAAGRLDPEAGVMLQMVWFDAGDQGGRLLVVAHHLVVDGVSWRILVPDLATAWAQVSA 6242 Query: 767 GQSIELPAGGTSFARWSALLAEHAKTDTVRDLA---DAWRAVTSVPQAL---PPVQPDTD 820 GQ L GTS RWS H + R+ A + WR V L P+ D Sbjct: 6243 GQEPTLEPVGTSMRRWS-----HGLVEATRERAGEIELWRRVLEADDPLIGSRPLDAAID 6297 Query: 821 TYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA---WTEFLNRSDTPIGV 877 T +++ + + T LL VP AF GV D LL A LA W V Sbjct: 6298 VAGTVEKVTVEVPADVTDALLTRVPEAFHGGVNDGLLTALALALAQWRRTHGDFTRESLV 6357 Query: 878 DVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQL 937 +EGHGR D++ DL RTVGWFT +PV L + + + AG A G VKA+KEQL Sbjct: 6358 SLEGHGREDQVLPGADLGRTVGWFTAMFPVRLDLSGIDLDDAFAGGKATGSAVKAIKEQL 6417 Query: 938 RSLPE-GLTYGLLRYLNPEVD---LGGSDPTIGFNYLGRL-GAGAGELSEELWRIDQXXX 992 ++P+ G+ YG+LRYL+PE + P + FNYLGRL GA + ++ W Sbjct: 6418 LAIPDHGIGYGMLRYLDPESADQLRALAKPQVTFNYLGRLGGATSTDIHGHAW-----VP 6472 Query: 993 XXXXXXXXVP---MPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFE 1049 +P +P+ +++NA T +G LRA+W + + L+ LW + Sbjct: 6473 VTDTKLDDIPASDIPVASALDINAVTGTGADGNRLRATWAFPTGVLTPSEVRALADLWVQ 6532 Query: 1050 ALAGICAHV-RGGGGGLTPSDVAPARLTQRQIDELSQRYD-VTDVLPLTPVQQGLLFHST 1107 AL + HV R GG+TPSD+ L Q ID L R+ ++D+ L+P+Q GLLFH+ Sbjct: 6533 ALTALTTHVARPDAGGVTPSDLDLVTLDQDAIDRLEARFPALSDIWSLSPLQSGLLFHAQ 6592 Query: 1108 FARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFV-EQFGEPVQVLTAD 1166 F+ D Y VQL + + G +D R+R A ++ RHPNL A FV + G Q++ Sbjct: 6593 FS-DASVDPYLVQLALKLRGNIDPDRIRRAGQALLDRHPNLRAAFVHDSAGASAQIIQQH 6651 Query: 1167 PMIAWRYLDLRGDDLTPD---HEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVL 1223 + W DL L PD E +++ A +RS D+ P R AL+R + +R +L Sbjct: 6652 VELPWSEFDLSA--LDPDETTREYDRIVARDRSVKFDMANAPLLRLALVRLTEEDYRLIL 6709 Query: 1224 TFHHIVIDGWSLPILLQEIFAGYF----GHRLPAAAPYRNFVNWLXXXXXXXXXXXWREV 1279 T HHI++DGWS P++++++ Y G LP YR++++W+ WR Sbjct: 6710 TNHHILLDGWSTPLVIRDLLTLYALDADGSLLPRVHSYRDYLSWMKRHDTTDSLDAWRTA 6769 Query: 1280 LDGFETPTLVAP--PGVPGPRGIE--SYRVSAETTRALGELARSQHTTINTVLQAAWTQL 1335 LDG E PTL+AP G E ++ +S E T L +L+R + T+NTV+Q AW + Sbjct: 6770 LDGVEEPTLLAPLERGEAHSAVAEETAFTLSEEQTTRLRDLSRERGLTLNTVVQTAWGIV 6829 Query: 1336 LMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHH 1395 L + G+ DV FG VSGRP +AG ESMVGL INT+P+R + ++G+LL ++QS Sbjct: 6830 LGGLVGRSDVVFGGTVSGRPPQIAGIESMVGLFINTLPVRVTLDPWESLGELLERVQSEQ 6889 Query: 1396 NDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELA---VTEFNNREYN 1452 L+H ++ L DI G FDTL ++ESYP+D + ++A VT + ++ Sbjct: 6890 AALLDHHYVGLTDIQSAVGGGGAFDTLTVFESYPVDEAGLTEQTDIAGMFVTGIDGKDSA 6949 Query: 1453 HYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDD 1512 HYPL+V+A L + EY VF+ S ++ + DR QR+L+A+ D P L+ M ++ + Sbjct: 6950 HYPLAVVASGDARLNFKFEYLPEVFEESAVDEIADRLQRVLDALADRPEIPLAHMQLLTE 7009 Query: 1513 DERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQ 1572 E L E+A V +P S +++P++F DP A+TFEG +++Y EL+E +NQ Sbjct: 7010 AE---LAEFA--PVRGRPGFSVRTLPQIFEDAAALDPNRTALTFEGRNVSYRELNERSNQ 7064 Query: 1573 LANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAK 1632 LA +L GA P VAL +PRS ++++A+ AV KTGAA++P+DP+ P R+E ML D+ Sbjct: 7065 LARVLISRGAGPETFVALGIPRSIESVLAVWAVAKTGAAFVPVDPNYPMDRIEHMLTDSG 7124 Query: 1633 PVAAVTTGDLRS---------RFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYT 1683 +T + D + PA+ + S S D+ AY++YT Sbjct: 7125 ATIGLTMAAYEKALPDSVPWLQLDSPKFEKACQSKPALPVADSDRRSPISLDNAAYIVYT 7184 Query: 1684 SGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGR 1743 SG+TG PKGV +TH + + A + + + FD SV+E A G Sbjct: 7185 SGSTGKPKGVVVTHEGLDNFAEDQRQRFAAAQTSRTLHFSTPSFDGSVFEYLQAFGVGAT 7244 Query: 1744 LVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGL-EGTALVVAGEACPTEVV 1802 +VI P ++ G +L L+ SE V + T +A+ + P GL E +V GEACP E+V Sbjct: 7245 MVIAPPTVYGGA-ELAELIRSEHVTHAFVTTAALSTVDPTGLDEFQHVVFGGEACPPELV 7303 Query: 1803 DRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGV 1862 RWA R + NAYGPTE+T+ A IS P++ G D + +G P+ VLD L+PVP GV Sbjct: 7304 TRWAPGRQLSNAYGPTETTVMANISDPMTVG-DPITLGGPIRGVGELVLDSRLQPVPVGV 7362 Query: 1863 VGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRAD 1922 GELY+ L+ RFVA PFGE G RMYRTGD+VRW D ++Y+GR+D Sbjct: 7363 PGELYITGAGLARGYHRRPELSSQRFVANPFGEAGERMYRTGDIVRWRADHTVEYVGRSD 7422 Query: 1923 EQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYI----TGTADPAAAR 1978 QVKIRG+RIELGEI ++ GV A + GD LV Y+ G DPA Sbjct: 7423 FQVKIRGFRIELGEIDNEIATFPGVSFAATLGVPGPSGDTVLVTYLLPNTAGGVDPAELT 7482 Query: 1979 SELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ-SAQRYRAPETETEKTLAG 2037 + L+ RLPA+MVP +V+ L+ +PLT GKLDR ALPAPE+ + ++ P + E+ + Sbjct: 7483 AHLSTRLPAHMVPTSVMFLDEIPLTPVGKLDRSALPAPEFHVTTTEFQPPTNDLERKIVD 7542 Query: 2038 IFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHV 2097 IFA VLG+ER A RVTA + ALD D+ VR LFEAP V L+ V Sbjct: 7543 IFADVLGIERIGIDDNFFDLGGNSLVATRVTARLRDALDTDIGVRALFEAPDVRSLAARV 7602 Score = 1272 bits (3291), Expect = 0.0 Identities = 816/2159 (37%), Positives = 1154/2159 (53%), Gaps = 113/2159 (5%) Query: 32 VLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPG 91 V+ P P T+P L A P A AL R TYR+LDE SNRLA +L G P Sbjct: 2848 VMDGPDAEPRTLPELLAAAASVDPKAAALSYEGREVTYRDLDERSNRLARLLIGRGIGPE 2907 Query: 92 ATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSR 151 + VA + RS E++LS+ +V KTGAA++PVDP +P RI M+SD+ ALT A+ R Sbjct: 2908 SVVALALARSPESVLSLWAVAKTGAAFVPVDPNYPTDRIVHMLSDSGAALALTVAEFRPT 2967 Query: 152 L-DQYDLAVIDMA--DPAI-----------DRRPSDALSGPRPDDLAYMTYTSGTTGVPK 197 L D V+D D + DR AL P AY+ YTSG+TG PK Sbjct: 2968 LPDCTSYVVVDAPGFDDEVSAHSAAVVTDADRTHPLALENP-----AYLIYTSGSTGTPK 3022 Query: 198 AVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESV 257 V VTH + + P + S FD S+ E+ A+ G +V+ P SV Sbjct: 3023 GVVVTHRGLANFATDERVRFGVTPRSRTLHFSSPSFDASILELLLAVGSGATMVIAPASV 3082 Query: 258 GSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAG-EACPTELVDRWAPG-R 315 + L ++L +V+ TP+A + P GL+ + G + CP ELV +W G R Sbjct: 3083 IGGTE-LADVLREGRVTHAFITPAAMASVDPAGLDQLECVATGGDVCPPELVAQWVTGGR 3141 Query: 316 VMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVA 375 M NAYGPTEAT+ ++++ P+ + VLD L P P GV GELYV+ Sbjct: 3142 RMFNAYGPTEATVVSSVTGPMIPGEGVTIGRPPMGTGEM-VLDSRLHPVPNGVTGELYVS 3200 Query: 376 GHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRG 435 G G+A GY R TA RFVA P+G G RMYRTGDL RW GQLEYLGR+D QVKIRG Sbjct: 3201 GSGLARGYKDRAGTTAERFVANPYGGLGARMYRTGDLARWNGAGQLEYLGRSDFQVKIRG 3260 Query: 436 YRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAQLRTALAESL 491 +RIELGEI+ AL + GV ++VV A G RLVGY+ TA DP + + L Sbjct: 3261 FRIELGEIETALTRYPGVARSVVSAHRGSTGANRLVGYLVPTAGAELDPEAVLEFVGGFL 3320 Query: 492 PAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLG 551 YMVP+A++VLD +PLT GKLDRRALP P++ + + RAP + E++LA ++A+VLG Sbjct: 3321 APYMVPSALIVLDELPLTPAGKLDRRALPEPDFGARVSTGRAPVSEMEEVLAGLFAEVLG 3380 Query: 552 VERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHV 611 +E GV+DSFF LGGDSI+S+Q+VARA+AAG+ PRD+F +T + V Sbjct: 3381 LESAGVEDSFFALGGDSIMSIQLVARAKAAGVVLTPRDVFEAKTVAGLAAVASWVGAADV 3440 Query: 612 V--DE----GVGPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTE-DDVVVILQALLD 664 V DE GVG + TPI +WL E G + +Q+ + AP + E + + QA+LD Sbjct: 3441 VVLDELPGGGVGDMPTTPITKWLLERGGEFNRMSQSALLTAPPNLRELEPLSATFQAVLD 3500 Query: 665 RHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVD--------ALTDDVLVE---A 713 RH LR ++ + ED+ L V G V A++ +R V A V+ E A Sbjct: 3501 RHDMLRAQLIVSAEDS---HLAVRPVGEVDAQDLIRRVPVSTAPGTRAFAATVIAELDAA 3557 Query: 714 RNRLDPAAGAMVSAVWV---RETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSI 770 +RLDPAAG MV VW +L+++ HHL VDGVSWRIL+ DL AWAQ GQ Sbjct: 3558 LDRLDPAAGVMVQVVWFDAGESGGRLLVVAHHLVVDGVSWRILVPDLATAWAQISAGQEP 3617 Query: 771 ELPAGGTSFARWSALLAEHAKTDTVRDLADAWRAVTSVPQAL---PPVQPDTDTYVTAGQ 827 L GTS RW+ L + A + D W+ + L P+ PD D T G+ Sbjct: 3618 VLEQVGTSMRRWAHGLVDEAASRAGE--LDLWQRILDCEDPLVGSRPLDPDIDVNATVGR 3675 Query: 828 LSASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLAWTEFL--------NRSDTPIGVDV 879 ++ L E + +L +P A V D LL A +A T++ RS V + Sbjct: 3676 VTVQLPAEVSEAVLTALPEAIHGSVNDGLLTALAMAVTQWRRTRGHTLHGRSVDGTLVSL 3735 Query: 880 EGHGRYDELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRS 939 EGHGR D++ DL RTVGWFT +PV L + + + G A G +KA+KEQL + Sbjct: 3736 EGHGREDQVVPGADLGRTVGWFTAMFPVRLDLSGIDLDDAFDGGKAAGSAIKAIKEQLLA 3795 Query: 940 LPE-GLTYGLLRYLNPEVD---LGGSDPTIGFNYLGRLGAGAGELSEELWRI--DQXXXX 993 +P+ G+ YG+LRYLN + S P I FNYLGR A +LSE R Sbjct: 3796 IPDHGMGYGMLRYLNADTAPLLAARSLPQISFNYLGRF---AADLSEAATRAGWTPTGEV 3852 Query: 994 XXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAG 1053 + P+ +++NA T + ++ P LRA+W +A + L+ LW AL Sbjct: 3853 DMDRAQDLDTPVTSAIDVNAVTTEVEDRPQLRATWAYAAGVLTVAEVRELAELWVRALTA 3912 Query: 1054 ICAH-VRGGGGGLTPSDVAPARLTQRQIDELSQRYD-VTDVLPLTPVQQGLLFHSTFARG 1111 + + R GG+TPSD+ L Q ID + R+ ++D+ L+P+Q GLLFH+ A Sbjct: 3913 LTTYAARPDAGGVTPSDLELVSLDQDAIDRIESRFPALSDIWSLSPLQSGLLFHALLADQ 3972 Query: 1112 IGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFV-EQFGEPVQVLTADPMIA 1170 D Y VQ+ + + G + R+R A ++ RH NL A FV ++ G PVQ + + Sbjct: 3973 TIDS-YTVQVTLELRGAVPS-RMRVAGQALLDRHANLRASFVYDEGGTPVQAIHGSAELP 4030 Query: 1171 WRYLDLRG-DDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIV 1229 W +DL G D + + EI +L A+R D+ P R LI+ G++ R ++T HHI+ Sbjct: 4031 WTEIDLSGLDAESREAEIVRLLDADRRRGFDMATPPLLRFMLIQIGGDEQRLIITNHHIL 4090 Query: 1230 IDGWSLPILLQEIFAGYF----GHRLPAAAPYRNFVNWLXXXXXXXXXXXWREVLDGFET 1285 +DGWS+P+L++++ Y LP PYR+++ W+ W+ L G E Sbjct: 4091 LDGWSMPLLIRDLLTLYATEGDATALPRVHPYRDYLAWMSHRSTEDSLGVWQRALAGVEE 4150 Query: 1286 PTLVAPPGVPGPRGIES----YRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTG 1341 PTL+AP +S + + T L LAR T++T+++ AW +L + G Sbjct: 4151 PTLLAPADASVQSDTQSSELLVELDVDRTDQLSVLAREHGLTLSTLIRTAWGIVLGGLVG 4210 Query: 1342 QRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEH 1401 + DV FG VSGRP +AG ESMVGL INT+P+R + T+G+LL ++Q L+H Sbjct: 4211 RSDVVFGGTVSGRPPQIAGIESMVGLFINTLPVRVVLDPRETLGELLERIQGEQAALLDH 4270 Query: 1402 EHLALNDIHHVSGHEQLFDTLFLYESYPIDTSAFMGVQELA----VTEFNNREYNHYPLS 1457 ++ L DI V+G FDTL ++ESYP+D ++A + ++ HYPL+ Sbjct: 4271 HYVGLTDIQSVAGPGAGFDTLTVFESYPVDREGLTDQTDIAGMHVLDVHDSANAAHYPLA 4330 Query: 1458 VMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQ 1517 ++A L L++EY +FD +++E + DR R L A+ + P +L+ + ++ D E + Sbjct: 4331 LIASAHENLQLKLEYVEELFDRADVERIGDRIVRALIALAEHPGMKLAQLRLLTDVEEAE 4390 Query: 1518 LDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLL 1577 L P S +++P++FA +A A+ F ++Y ELDE +NQLA LL Sbjct: 4391 L-----VPARGLPGRSVRTLPQMFAETAAAAGDATALVFGDRRMSYRELDERSNQLARLL 4445 Query: 1578 AVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAV 1637 G P VAL + RS ++++A+ ++ KTGAA++P+DP+ P R+E M+ D+ + Sbjct: 4446 IDRGVGPEDIVALGISRSIESVLAVWSITKTGAAFVPVDPTYPRERVEHMVTDSGCTFGL 4505 Query: 1638 TTGDLRSRF-DGFDLQVVEVDDPAVEIYPSTTLLTPSPDDI--------AYMIYTSGTTG 1688 R D ++ + A I +T D + AY+IYTSG+TG Sbjct: 4506 RLEADHGRLPDTVRWLTLDDTETATAIRAMSTDTVTDDDRVAPLRFAHPAYVIYTSGSTG 4565 Query: 1689 VPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVP 1748 PKGV ++H + + + + S FD SV E + G +VIVP Sbjct: 4566 KPKGVVVSHRGLDNFAEEQRTRYATDSTSRALHFSSPSFDASVLEYLLSFAVGATMVIVP 4625 Query: 1749 ESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVVA-GEACPTEVVDRWAV 1807 S+ G ++L L+ +EGV + TP+A+ + PEGLE VVA GEA P E+V RWA Sbjct: 4626 PSVYGG-EELAELIRTEGVTHGFVTPAALASVDPEGLEVFQNVVAGGEAVPPELVTRWAP 4684 Query: 1808 DRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELY 1867 R M N YGPTE+TI + +S L G + V IG+PV + +LD L+PV GV GELY Sbjct: 4685 GRTMYNGYGPTETTIMSNLSDHLQVG-ETVTIGAPVRGVSEVILDSRLQPVSVGVAGELY 4743 Query: 1868 LAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKI 1927 ++ LT RFVA P+GEPG RMYRTGDL RW D ++YLGR D QVKI Sbjct: 4744 ISGEGLARGYHARAGLTSERFVANPYGEPGDRMYRTGDLARWRSDHTVEYLGRTDFQVKI 4803 Query: 1928 RGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSEL----TN 1983 RG+RIELG+I +AL+ V AV + R GD LV Y+ A+ A EL N Sbjct: 4804 RGFRIELGDIDSALAAHPSVAFAVTLGRPGPAGDTVLVSYVLPEAESALEPPELKEWTAN 4863 Query: 1984 RLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGIFAHV 2042 LPA+MVP++++ L+ +PLT GKLDR ALP P++ ++ +R P T E T+A + V Sbjct: 4864 LLPAHMVPSSIMILDEIPLTPVGKLDRAALPEPQFLPTSDDFRPPSTVLEHTIADVITTV 4923 Query: 2043 LGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDA 2101 LG+ER A RV A + LD D+ VRTLFEAPT+ +L+ +E A Sbjct: 4924 LGIERVGIDDNFFDIGGNSLIATRVAARLTAELDTDIGVRTLFEAPTIHQLARLIESTA 4982 Score = 502 bits (1292), Expect = e-139 Identities = 364/1074 (33%), Positives = 535/1074 (49%), Gaps = 90/1074 (8%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +P++ Q+ + F + F Y + L + +TG LD LR AV V RH +L F Sbjct: 5005 VPVSLAQKRMWFLNQF--DTSSAAYNIPLAVRLTGHLDVESLRAAVTDVFVRHESLRTVF 5062 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALI 1212 GEP QV+ + W +L +++ D E+ + A +A D+ R+AL Sbjct: 5063 PSHDGEPTQVVLSPGQ--WTP-NLEIVEVSED-ELREHIAGLATAGFDVTADVPMRSALF 5118 Query: 1213 RTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAP--------YRNFVNWL 1264 + + H V+ HHI DG+SL L +++ Y R+ +AP Y ++ W Sbjct: 5119 ALAPDDHVLVIVVHHICADGFSLTPLARDVMTAYAA-RIAGSAPQWNPLSVQYADYTLWQ 5177 Query: 1265 XXXXXXXXXXX---------WREVL----DGFETPTLVAPPGVPGPRGIE-SYRVSAETT 1310 W + L + + PT A P RG + + + A+ Sbjct: 5178 LQLLGDESDAESLISQQLRYWTDQLADLPELLQLPTDRARPVQQSFRGAQVDFTIPADVH 5237 Query: 1311 RALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLIN 1370 RAL LAR ++T+ + AA + LL ++ D+A GT ++GR A + MVG+ +N Sbjct: 5238 RALAALARKHNSTMFMAVHAALSVLLSALSSTEDIAVGTPIAGRGD--AALDDMVGMFVN 5295 Query: 1371 TVPIRAKVSADTTVGDLLRQLQS------HHNDTLEHEHLALNDIHHVSGHEQLFDTLFL 1424 T+ +R+ V G L+ Q++S HH+D + + + H LF L Sbjct: 5296 TLVLRSAVDPAAGFGALMDQVRSTDLAAFHHSDLPFERLVDVLAPERSTAHSPLFQALLE 5355 Query: 1425 YESYPIDTSAFMGVQEL--AVTEFNNREYNHYPLSVMALPGHE-------LGLRVEYDTS 1475 + + + + + + EL A +F + E + L + G + + + T Sbjct: 5356 FRN---NETPRLELPELTAAAVDF-DLEVAKFDLQLSVEEGFDADGVASGIAASFIFATD 5411 Query: 1476 VFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQ 1535 +FD + T DRF R+L A+ DP + + + D ER+ + N A D Sbjct: 5412 LFDAGTVRTFADRFLRILGAVTSDPLAPVGDIVITDAAERSAMATEWNTAGFDAGTD--- 5468 Query: 1536 SIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRS 1595 ++ + FA+ V R P+A AVT E +L Y ELD +N+LA LL G P VA+ +PR+ Sbjct: 5469 TLADRFAQSVARFPDATAVTSEDVALTYAELDARSNRLARLLISQGVGPETLVAVALPRT 5528 Query: 1596 ADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVE 1655 D I+A+LAV+KTG YLP+D + PA RL F+ DA P +TT S + + Sbjct: 5529 CDLIIALLAVIKTGGGYLPVDITYPADRLAFVFEDAAPNCVITTTGDVSALPDSETPAIL 5588 Query: 1656 VDDP-----AVEIYPSTTL----LTP-SPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLD 1705 +DDP + P+T +TP +AY+IYTSG+TG PKGV ++H NV + Sbjct: 5589 LDDPETTADLAQQSPATITDADRVTPLDSSSVAYVIYTSGSTGRPKGVVVSHRNVLTLFA 5648 Query: 1706 TLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSE 1765 VW+ +HS FD SVWE+WG LL+GGRLV+V A SP+ H LL +E Sbjct: 5649 NTQPLYGFDENDVWTMFHSYAFDFSVWELWGPLLYGGRLVVVDYYTARSPEMFHELLRNE 5708 Query: 1766 GVNVLYQTPSAV-------RMMSPEGLEGTAL-----VVAGEACPTEVVDRWAVDR---- 1809 V VL QTP+A R++S + AL + GEA + RW Sbjct: 5709 QVTVLNQTPTAFYQLAETDRIVSEIDVNAAALALRYVIFGGEALDLGQLGRWYSRHDDSA 5768 Query: 1810 -VMINAYGPTESTI---YAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGE 1865 ++N YG TE+T+ Y A+ + + IG + VLD L PVPPG +GE Sbjct: 5769 PTLVNMYGITETTVHVSYLALDREFAESASASVIGRGIAGLHVHVLDRRLHPVPPGTIGE 5828 Query: 1866 LYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQV 1925 +Y++ L+ +RFVA P PGARMYRTGDL RW DGQL+YLGR+D QV Sbjct: 5829 MYVSGDQVTRGYLGRAGLSSSRFVADPL-RPGARMYRTGDLARWNTDGQLEYLGRSDFQV 5887 Query: 1926 KIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAAARSEL 1981 KIRG+RIELGEI++AL G+ QAVV+ R+D G RL+GY+ T + ++A + Sbjct: 5888 KIRGFRIELGEIESALLRYRGIAQAVVLTRDDGHGGHRLIGYVVPESGATVEVSSALEFV 5947 Query: 1982 TNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFA 2040 +L +YMVPA +V L+ LPLT NGKLDRRALP P++ + RAP TE E LAG+FA Sbjct: 5948 GTQLTSYMVPATLVVLDALPLTSNGKLDRRALPEPDFGARVSAGRAPATEMETVLAGLFA 6007 Query: 2041 HVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 VLG+E ++++ A A L+ R +FEA TVA L+ Sbjct: 6008 EVLGLESVGVDDSFFALGGDSIMSIQLVARAKAA-GVVLTPRDVFEAKTVAALA 6060 Score = 482 bits (1240), Expect = e-133 Identities = 347/1059 (32%), Positives = 509/1059 (48%), Gaps = 78/1059 (7%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D LP++ Q+ + F + F + Y + L + +TG LD+ ++DAV V+ RH +L Sbjct: 2394 DRLPVSLAQKRMWFINQF--DLDSPAYNIALAVRLTGDLDEDAMQDAVADVMDRHESLRT 2451 Query: 1151 RFVEQFGEPVQVLTADPMIAWRYLDLRGDDLTP----DHEIEQLCAAERSAVCDLLERPT 1206 RF GEPVQV+ + DL+P + E+ + + A D+ Sbjct: 2452 RFPMVEGEPVQVILPTEDVV--------PDLSPIATTEAELPEHISRLAGAGFDVTVSVP 2503 Query: 1207 FRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHR-------LPAAAPYRN 1259 RAAL RT +H V+ HHI DG+S+ L +++ Y P Y + Sbjct: 2504 VRAALFRTDPGEHVLVIVVHHISADGFSMAPLARDVMTAYAARTGGQAPDWTPLPVQYAD 2563 Query: 1260 FVNWLXXXXXXXXXXX---------WREVLDGFETPTLVA-PPGVPGPR------GIESY 1303 F W W L G P L+A P P P GI S+ Sbjct: 2564 FALWQHRVLGNADDPDSLLAAQLDYWTHTLAGL--PELLALPTDHPRPTQQSMRGGIHSF 2621 Query: 1304 RVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAES 1363 + + L AR ++++ + AA LL R+ DV+ GT ++GR A + Sbjct: 2622 SIDPQVHSRLITTAREHNSSVFMAVHAALAVLLARLGDTDDVSVGTPIAGRGD--AALDD 2679 Query: 1364 MVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQ 1417 MVG+ +NT+ +R V T DLL ++ + H L + + H Sbjct: 2680 MVGMFVNTLVLRTPVEPAGTFTDLLSTVRDTDLNAFHHADLPFERLVDAISPERATSHSP 2739 Query: 1418 LFDTLFLYESYPIDTSAFMGVQELAV---TEFNNREYNHYPLSVMALPGHELGLRVE--Y 1472 LF + + + G+ + T+ +N + G G+ Y Sbjct: 2740 LFQVVLEFRNNERPRLELPGLTVTGLDLATDISNFDLQLTLTEEFGASGEPAGISAAFTY 2799 Query: 1473 DTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVD 1532 +S+FD S I D QR+ +A+ +P + +D++ ER L V+ P Sbjct: 2800 ASSLFDASTIAGFADYLQRIFDAVTSEPGMAVGDIDLMVASERAALTP-----VMDGPDA 2854 Query: 1533 SPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMV 1592 P+++PE+ A DP+A A+++EG + Y +LDE +N+LA LL G P VAL + Sbjct: 2855 EPRTLPELLAAAASVDPKAAALSYEGREVTYRDLDERSNRLARLLIGRGIGPESVVALAL 2914 Query: 1593 PRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQ 1652 RS ++++++ AV KTGAA++P+DP+ P R+ ML D+ A+T + R Sbjct: 2915 ARSPESVLSLWAVAKTGAAFVPVDPNYPTDRIVHMLSDSGAALALTVAEFRPTLPDCTSY 2974 Query: 1653 VVEVDDPAV--EIYPSTTLLTPSPD--------DIAYMIYTSGTTGVPKGVAITHGNVTQ 1702 VV VD P E+ + + D + AY+IYTSG+TG PKGV +TH + Sbjct: 2975 VV-VDAPGFDDEVSAHSAAVVTDADRTHPLALENPAYLIYTSGSTGTPKGVVVTHRGLAN 3033 Query: 1703 VLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALL 1762 P + + S FD S+ E+ A+ G +VI P S+ G +L +L Sbjct: 3034 FATDERVRFGVTPRSRTLHFSSPSFDASILELLLAVGSGATMVIAPASVIGG-TELADVL 3092 Query: 1763 VSEGVNVLYQTPSAVRMMSPEGLEGTALV-VAGEACPTEVVDRWAV-DRVMINAYGPTES 1820 V + TP+A+ + P GL+ V G+ CP E+V +W R M NAYGPTE+ Sbjct: 3093 REGRVTHAFITPAAMASVDPAGLDQLECVATGGDVCPPELVAQWVTGGRRMFNAYGPTEA 3152 Query: 1821 TIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXX 1880 T+ ++++ P+ PG V IG P VLD L PVP GV GELY++ Sbjct: 3153 TVVSSVTGPMIPGEGVT-IGRPPMGTGEMVLDSRLHPVPNGVTGELYVSGSGLARGYKDR 3211 Query: 1881 XXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAA 1940 T RFVA P+G GARMYRTGDL RW GQL+YLGR+D QVKIRG+RIELGEI+ A Sbjct: 3212 AGTTAERFVANPYGGLGARMYRTGDLARWNGAGQLEYLGRSDFQVKIRGFRIELGEIETA 3271 Query: 1941 LSDVDGVDQAVVIAREDRPGDKRLVGYITGTA----DPAAARSELTNRLPAYMVPAAVVT 1996 L+ GV ++VV A G RLVGY+ TA DP A + L YMVP+A++ Sbjct: 3272 LTRYPGVARSVVSAHRGSTGANRLVGYLVPTAGAELDPEAVLEFVGGFLAPYMVPSALIV 3331 Query: 1997 LETLPLTVNGKLDRRALPAPEYQS-AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXX 2055 L+ LPLT GKLDRRALP P++ + RAP +E E+ LAG+FA VLG+E Sbjct: 3332 LDELPLTPAGKLDRRALPEPDFGARVSTGRAPVSEMEEVLAGLFAEVLGLESAGVEDSFF 3391 Query: 2056 XXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 ++++ A A L+ R +FEA TVA L+ Sbjct: 3392 ALGGDSIMSIQLVARAKAA-GVVLTPRDVFEAKTVAGLA 3429 Score = 474 bits (1220), Expect = e-131 Identities = 350/1089 (32%), Positives = 524/1089 (48%), Gaps = 112/1089 (10%) Query: 1091 DVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAA 1150 D +PL+ Q+ + F + F Y + L + +TG LD+ LR A+ V+ RH L Sbjct: 7621 DRIPLSLAQKRMWFLNQF--DTSSPAYNIPLAVRLTGTLDEDALRLAMADVLERHETLRT 7678 Query: 1151 RFVEQFGEPVQVL--TADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFR 1208 F EP Q + AD + + +DL P H ++ + S D+ R Sbjct: 7679 VFPTVDNEPTQRILPAADAQPGVDTVSVAAEDL-PRHIMDLV-----SRGFDVSTDVPVR 7732 Query: 1209 AALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL--------PAAAPYRNF 1260 AAL R + + H + HHI DG+SL L +++ Y RL P Y ++ Sbjct: 7733 AALFRIAPDHHVLTIVVHHISADGFSLAPLARDVMVAYTS-RLGGDGPQWDPLHVQYADY 7791 Query: 1261 VNWL---------XXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIE--------SY 1303 W W E L G P ++ P PR I+ + Sbjct: 7792 TLWQHAGLGSENDPESMINQQLRFWSETLAG--VPDVIQLP-TDRPRPIQQTFEGDRVEF 7848 Query: 1304 RVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAES 1363 + A+ + L LAR+ + T+ + AA LL R+ DV GT V+GR A + Sbjct: 7849 AIDADLHQRLTALARANNATMFMAVHAALAVLLSRLGSTDDVVIGTPVAGRGE--AALDD 7906 Query: 1364 MVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLF 1423 MVG+ +NT+ +R ++ +T +L+++++ +H L E+L + Sbjct: 7907 MVGMFVNTLVLRNRIDPASTFTELVQRIRETDLAAFQHSDLPF---------ERLVE--- 7954 Query: 1424 LYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLRV------------- 1470 E P ++++ + ++A+ EF N E L + + +L +V Sbjct: 7955 --ELNPTRSTSYSPLFQVAL-EFQNNENPTLELPDLRVENVDLETKVVKEDLEVILAEQF 8011 Query: 1471 -------------EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQ 1517 ++ S+FD ++ DRF R+L A+ DP R + ++ ++D+ E + Sbjct: 8012 DQDGAPAGVAGGLDFAVSLFDRGTARSIADRFVRILAAVTADPDRPIGTLPLLDEAEIEE 8071 Query: 1518 LDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLL 1577 + + P P+ P++ DP++ A++FE + Y ELDE +N+LA +L Sbjct: 8072 MVPARGK-----PDVRPEVWPDLLTAAAALDPDSVALSFEDRQVTYRELDEWSNRLARVL 8126 Query: 1578 AVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAV 1637 G P VA+ +PRS + +V+I +V K+GAA++P+DP+ P R+++ML D + + Sbjct: 8127 CAQGVGPETFVAIGMPRSIEEVVSIWSVAKSGAAFVPVDPTYPRDRIDYMLTDCRASVGL 8186 Query: 1638 TTGDLRSRF-----------DGFDLQVVEV-DDPAVEIYPSTTLLTPSPDDIAYMIYTSG 1685 T R + F QV V P + + L P AY+IYTSG Sbjct: 8187 TVAGRRDNLPDTVPWLVLDDESFAEQVAAVSSSPVTDADRTRPLHLAHP---AYLIYTSG 8243 Query: 1686 TTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLV 1745 +TG PKGV +TH + + + S S FD S++E+ A R+V Sbjct: 8244 STGKPKGVIVTHRGMANLTAEEHERFQVTHESRVSHLASPSFDASIFELMMAFGASARVV 8303 Query: 1746 IVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG-TALVVAGEACPTEVVDR 1804 IVP ++ G +L L V + TP+A+ + GLE L VAGEACP E+V+ Sbjct: 8304 IVPPTVFGG-TELADLFRRNAVTHAFITPTALSSIEDVGLESLRVLAVAGEACPPELVEI 8362 Query: 1805 WAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVG 1864 W R M N YGPTE+TI A++SAP+ PG VV IG+P + VLDE L+PVP GV G Sbjct: 8363 WGKHRNMHNGYGPTETTIQASVSAPMRPGG-VVNIGAPALGFGSLVLDERLQPVPVGVPG 8421 Query: 1865 ELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQ 1924 ELY+ LT RFVACPFGEPG RMYRTGD+VRW D ++Y+GR D Q Sbjct: 8422 ELYITGPGLARGYHNRSALTSERFVACPFGEPGRRMYRTGDVVRWRGDHTIEYIGRTDFQ 8481 Query: 1925 VKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGT----ADPAAARSE 1980 VK+RG+RIELGEI A L+ V A I GD L Y+ +PA R+ Sbjct: 8482 VKVRGFRIELGEIDAVLARHPAVAFAATIGHTGPSGDTLLASYVRAAEGHDLEPAELRTH 8541 Query: 1981 LTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGIF 2039 +RLPA+MVP+AVV L+ +P+T GKLDR+ALPAPE+ + +RAP T TE+ + F Sbjct: 8542 AADRLPAHMVPSAVVVLDQIPMTPVGKLDRKALPAPEFGTTGAAFRAPTTATERIIVEAF 8601 Query: 2040 AHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHV-- 2097 A VLGV+R A RV + L + ++++F PT A L+L V Sbjct: 8602 AEVLGVDRVGTADSFFDLGGNSIVATRVITVLQERLGRQIPLQSMFLDPTPAGLALRVDT 8661 Query: 2098 EHDAGERTD 2106 E+ AG D Sbjct: 8662 ENAAGSPVD 8670 Score = 454 bits (1168), Expect = e-125 Identities = 339/1054 (32%), Positives = 490/1054 (46%), Gaps = 72/1054 (6%) Query: 1117 YAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDL 1176 Y + + I + G LD LR AV V+ RH +L F P+QV+ ++ +LD Sbjct: 1350 YNIPVGIRLRGTLDVEALRTAVSDVLTRHESLRTVFPNTPNGPIQVVLPVAEVS-PHLDA 1408 Query: 1177 RGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLP 1236 ++E+E A+ + D+ P RA L RT+ + H V HHI DG S+ Sbjct: 1409 VE---VAENELESRLIADAATGFDVTVEPPIRAELYRTATDDHVLVFVVHHIAADGLSMT 1465 Query: 1237 ILLQEIFAGYFGHRL-------PAAAPYRNFVNWLXXXXXXXXXXX---------WREVL 1280 L +++ Y P Y +F W W L Sbjct: 1466 PLTRDVMVAYHARAAGDTPQWAPLEVQYADFAVWQRELLGSPDDPTSLLARQLAFWARTL 1525 Query: 1281 DG----FETPTLVAPPGVPGPRGIES-YRVSAETTRALGELARSQHTTINTVLQAAWTQL 1335 DG + PT P G + + + A AL E+A + ++ V+ AA L Sbjct: 1526 DGAPEVMDLPTDRPRPARQSMIGATADFSIPARIHAALLEIAGANDASLFMVVHAALAVL 1585 Query: 1336 LMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQS-- 1393 L R +G DV+ G+ VSGR + +VG+ +NTV +R V D + ++L +S Sbjct: 1586 LSRSSGSSDVSIGSPVSGRGE--RQLDDVVGMFVNTVVLRTTVDPDRSFPEILSHTRSVD 1643 Query: 1394 ---HHNDTLEHEHLALNDIHHV--SGHEQLFDTLFLYESYPIDTSAFMGVQ------ELA 1442 N L +E L ++++ H LF + + + + G+ E Sbjct: 1644 LAAFSNTDLPYERL-VDELKPTRSEAHSPLFQVMLVLQGFANTRLELPGLDVEVEALETG 1702 Query: 1443 VTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPAR 1502 +F+ + PG + ++ Y + +FD + L +RF LLE + Sbjct: 1703 AAKFDLQVILTEHTEESGAPG-AIDVQFSYASELFDPPTMTALAERFVTLLETITAGSDA 1761 Query: 1503 RLSSMDVVDDDE-RTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESL 1561 ++ +D++ DE L++W + V V ++ +F QV R P+A AV F E L Sbjct: 1762 KVGDIDLIGADETHRMLEQWIDTDVA---VPDSATLVSLFEAQVARTPDAVAVVFAEEEL 1818 Query: 1562 NYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPA 1621 Y E D AN+LA L G P VA+ + RS + ++AI AV KTGAAY+P+DP PA Sbjct: 1819 LYAEFDARANRLARELLARGVGPESRVAVALRRSLELMIAIYAVEKTGAAYVPLDPDHPA 1878 Query: 1622 ARLEFMLGDAKPVAAVTTGDLRSRFDGFD----LQVVEVDDPAVEIYPSTTLLTPS---- 1673 +R+ +++ A+P +T+ R R +G D V+E+D + PST + Sbjct: 1879 SRIAYVIESAEPACVLTSS--RDRCEGVDSAAGAAVIEIDTLNLSRRPSTPITAAERGGP 1936 Query: 1674 --PDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSV 1731 PD AY+IYTSG+TG PKGVA++H + L + V Q + FDVSV Sbjct: 1937 IHPDSTAYVIYTSGSTGRPKGVAVSHRAIVNRLLWMQDTYRMDHTDVVLQKTPVTFDVSV 1996 Query: 1732 WEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMS----PEGLEG 1787 WE++ L G RLV+ P L ++ V ++ PS + + + PE L G Sbjct: 1997 WELFWPLEVGARLVLAAPDGHRDPTYLSHIIADHQVTTMHFVPSMLAVFTAGAEPE-LCG 2055 Query: 1788 TALVV--AGEACPTEVVDRWAV--DRVMINAYGPTESTIYAAISAPLSPGSDVVPIGSPV 1843 + V +GEA P D + + N YGPTE+ + VPIG+PV Sbjct: 2056 SLRQVFCSGEALPPATADAFREFGSAALHNLYGPTEAAVDVTYWECTEGDRASVPIGAPV 2115 Query: 1844 PKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRT 1903 +VLD L PVP GV GELYLA LT RFVA PFG PG RMYRT Sbjct: 2116 WNTQVYVLDSRLHPVPVGVHGELYLAGIQLARGYVGRSDLTSDRFVANPFGAPGQRMYRT 2175 Query: 1904 GDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKR 1963 GD+VRW DG ++Y+GR D QVK+RG RIELGE++AA+ V QAVV + Sbjct: 2176 GDVVRWRADGNIEYIGRRDFQVKLRGQRIELGEVEAAVLAHPSVAQAVVTVHRSEATGES 2235 Query: 1964 LVGYITGTA----DPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQ 2019 LVGY+ A D A R LPAYMVP ++ L+ PL GKLDR ALP PE+ Sbjct: 2236 LVGYVIPVAGADIDTAVVRDAAAEALPAYMVPTRIIVLDRFPLGATGKLDRGALPEPEFL 2295 Query: 2020 S-AQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDAD 2078 S + + P E+ LA IFA +L R A R+ A VN AL + Sbjct: 2296 SPSAEFVTPRNPIEEILASIFADLLDAPRIGVYDSFFDLGGNSLVATRLVARVNAALGSR 2355 Query: 2079 LSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAA 2112 + VR +F+APTVA L+ +E +A + +R A Sbjct: 2356 IGVREIFDAPTVATLATRIESEAVQGAERPPLVA 2389 Score = 443 bits (1140), Expect = e-121 Identities = 335/953 (35%), Positives = 462/953 (48%), Gaps = 63/953 (6%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TAEP T + DLL++ E+ ++ V +P P T+P L A V D AL Sbjct: 697 VTAEP-TAPIGDVDLLEQVEYAELA-----PVRDEPSVEPRTLPTLLARAVEAGGDGDAL 750 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 V R+ TY ELD S+RLA +L HG PG+ VA I RS E++L+ +V K+GAA++P Sbjct: 751 VYQGRTLTYPELDAQSDRLARMLIGHGVGPGSVVALAIARSIESVLATWAVAKSGAAFVP 810 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDR----------R 170 VDP +P RI M++D+ V LT A RS L + ++ M D + R Sbjct: 811 VDPNYPADRIEHMLTDSGAVVGLTVAAHRSSLPETTPWLV-MDDASFGRDLAQHAAGTVA 869 Query: 171 PSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHS 230 +D L R D AY+ YTSG+TG PK V VTH + G + S Sbjct: 870 DADRLRPLRTADPAYLIYTSGSTGTPKGVVVTHAGLANFAEDERQRFAVTAGSRTLHFSS 929 Query: 231 LVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEG 290 FD S+ E+ A+ G +VV P +V + L +LL E+V+ TP+A + P G Sbjct: 930 PSFDASILELLLAVGAGATMVVAPSTVYGGTE-LADLLSRERVTHAFVTPAALASVDPTG 988 Query: 291 LESTTLIVAG-EACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXX 349 L+ +V G E+CP LV +WAPGRVM NAYGPTEAT+ A+++ PL Sbjct: 989 LDHIRCVVTGGESCPPALVAQWAPGRVMFNAYGPTEATVVASVAGPLTVGEPVTIGRPSR 1048 Query: 350 XXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRT 409 L VLD L P P GV GELY+ G GVA GY R TA RFVA P G GERMYRT Sbjct: 1049 GCG-LLVLDSRLHPVPRGVPGELYITGDGVARGYHNRSIPTAERFVADPHGAPGERMYRT 1107 Query: 410 GDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKR 469 GDL RW + GQLEYLGR D QVKIRG+RIELGEI A + V A + R GD Sbjct: 1108 GDLARWNAAGQLEYLGRTDFQVKIRGFRIELGEIDAVVRSHPSVAFATTVGRTAPSGDTV 1167 Query: 470 LVGYI---TGT-ADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYR 525 LV Y+ GT + A +LPA+MVP V+VL +PLT GKLDR+ALP P++ Sbjct: 1168 LVTYVLPEDGTDIVVGDILEHAAAALPAHMVPARVMVLREVPLTPAGKLDRKALPEPQFE 1227 Query: 526 SAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQ 584 + + YRAP TP E +A+V+A +LGVER+GVDDSFFDLGGDS+++ +VV+R AA + Sbjct: 1228 ATSTVYRAPVTPTEMQIAEVFAALLGVERIGVDDSFFDLGGDSLVATRVVSRVNAALSTE 1287 Query: 585 CRPRDIFVEQTXXXXXXXXXXXXESH------VVDEGVGPV---VATPIMRWLREVDGPT 635 D+F + G GPV +A M ++ ++D + Sbjct: 1288 IGVLDLFEAPSVALLSARVDALGPRTSARPVLAPRAGSGPVQVSLAQQRMWFINQLDTAS 1347 Query: 636 GQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLV----PEAG 691 +N V + + + + + +L RH +LR +T + L V P Sbjct: 1348 PAYNIPVGIRLRGTLDVEALRTAVSDVLTRHESLRTVFPNTPNGPIQVVLPVAEVSPHLD 1407 Query: 692 AVGARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ---LVLMIHHLAVDGV 748 AV E + L ++ +A D + A R + LV ++HH+A DG+ Sbjct: 1408 AVEVAE-----NELESRLIADAATGFDVTVEPPIRAELYRTATDDHVLVFVVHHIAADGL 1462 Query: 749 SWRILLEDLNIAWAQHCTG---QSIELPAGGTSFARWSALLAEHAKTDT---VRDLADAW 802 S L D+ +A+ G Q L FA W L T R LA Sbjct: 1463 SMTPLTRDVMVAYHARAAGDTPQWAPLEVQYADFAVWQRELLGSPDDPTSLLARQLAFWA 1522 Query: 803 RAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVA 859 R + P+ + + D + A+ D ++ L E+ A A + ++ A Sbjct: 1523 RTLDGAPEVM-DLPTDRPRPARQSMIGATADFSIPARIHAALLEIAGANDASLFMVVHAA 1581 Query: 860 FGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVE 912 + + SD IG V G G + L VG F + TV+ Sbjct: 1582 LAVLLSRSSGSSDVSIGSPVSGRG-------ERQLDDVVGMFVNTVVLRTTVD 1627 Score = 431 bits (1108), Expect = e-118 Identities = 300/853 (35%), Positives = 423/853 (49%), Gaps = 41/853 (4%) Query: 1296 GPRGIESYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRP 1355 G + + V AE R LA T I T L AA LL R+ DV GT + GR Sbjct: 492 GAGEVVGFAVDAEVQRRAALLAEEAGTGIFTALHAALAVLLGRLGDTDDVVIGTPIVGRE 551 Query: 1356 ADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG- 1414 A + G N +R++V ++ D L +++ H L +D+ G Sbjct: 552 A-ADSDDPEAGAFFNKTVLRSQVDTASSFVDHLSRVRDADRAAFTHAALPFDDLVAALGA 610 Query: 1415 -----HEQLFDTL--FLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLS-VMALPGHEL 1466 H LF + F +P D+S + V + RE+ L V +L E Sbjct: 611 ESDPSHTPLFQVMLEFTDGGHPHDSSGNVTVSPI------QREHRALGLDLVFSLTESES 664 Query: 1467 GL---RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWAN 1523 G R+ + T V+D + E L RF R+L+ + +P + +D+++ E +L Sbjct: 665 GGINGRLRFATDVWDRASAEALAARFVRILQTVTAEPTAPIGDVDLLEQVEYAEL----- 719 Query: 1524 RAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAA 1583 V +P P+++P + AR VE + A+ ++G +L Y ELD +++LA +L +G Sbjct: 720 APVRDEPSVEPRTLPTLLARAVEAGGDGDALVYQGRTLTYPELDAQSDRLARMLIGHGVG 779 Query: 1584 PGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLR 1643 PG VAL + RS ++++A AV K+GAA++P+DP+ PA R+E ML D+ V +T R Sbjct: 780 PGSVVALAIARSIESVLATWAVAKSGAAFVPVDPNYPADRIEHMLTDSGAVVGLTVAAHR 839 Query: 1644 SRFDGFDLQVVEVD---------DPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVA 1694 S +V D A + + L D AY+IYTSG+TG PKGV Sbjct: 840 SSLPETTPWLVMDDASFGRDLAQHAAGTVADADRLRPLRTADPAYLIYTSGSTGTPKGVV 899 Query: 1695 ITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGS 1754 +TH + + G+ + S FD S+ E+ A+ G +V+ P ++ G Sbjct: 900 VTHAGLANFAEDERQRFAVTAGSRTLHFSSPSFDASILELLLAVGAGATMVVAPSTVYGG 959 Query: 1755 PDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEGTALVV-AGEACPTEVVDRWAVDRVMIN 1813 +L LL E V + TP+A+ + P GL+ VV GE+CP +V +WA RVM N Sbjct: 960 -TELADLLSRERVTHAFVTPAALASVDPTGLDHIRCVVTGGESCPPALVAQWAPGRVMFN 1018 Query: 1814 AYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXX 1873 AYGPTE+T+ A+++ PL+ G + V IG P VLD L PVP GV GELY+ Sbjct: 1019 AYGPTEATVVASVAGPLTVG-EPVTIGRPSRGCGLLVLDSRLHPVPRGVPGELYITGDGV 1077 Query: 1874 XXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIE 1933 T RFVA P G PG RMYRTGDL RW GQL+YLGR D QVKIRG+RIE Sbjct: 1078 ARGYHNRSIPTAERFVADPHGAPGERMYRTGDLARWNAAGQLEYLGRTDFQVKIRGFRIE 1137 Query: 1934 LGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELTNR----LPAYM 1989 LGEI A + V A + R GD LV Y+ ++ LPA+M Sbjct: 1138 LGEIDAVVRSHPSVAFATTVGRTAPSGDTVLVTYVLPEDGTDIVVGDILEHAAAALPAHM 1197 Query: 1990 VPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVERX 2048 VPA V+ L +PLT GKLDR+ALP P++++ YRAP T TE +A +FA +LGVER Sbjct: 1198 VPARVMVLREVPLTPAGKLDRKALPEPQFEATSTVYRAPVTPTEMQIAEVFAALLGVERI 1257 Query: 2049 XXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRV 2108 A RV + VN AL ++ V LFEAP+VA LS V+ + R Sbjct: 1258 GVDDSFFDLGGDSLVATRVVSRVNAALSTEIGVLDLFEAPSVALLSARVDALGPRTSARP 1317 Query: 2109 SFAAVHGSDVTEV 2121 A GS +V Sbjct: 1318 VLAPRAGSGPVQV 1330 Score = 430 bits (1105), Expect = e-117 Identities = 284/767 (37%), Positives = 404/767 (52%), Gaps = 47/767 (6%) Query: 36 PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA 95 PG + T+P +F + P+ AL R+ +YREL+E SN+LA VL GA P VA Sbjct: 7022 PGFSVRTLPQIFEDAAALDPNRTALTFEGRNVSYRELNERSNQLARVLISRGAGPETFVA 7081 Query: 96 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLD-- 153 IPRS E++L++ +V KTGAA++PVDP +P RI M++D+ LT A L Sbjct: 7082 LGIPRSIESVLAVWAVAKTGAAFVPVDPNYPMDRIEHMLTDSGATIGLTMAAYEKALPDS 7141 Query: 154 ----QYDLAVIDMA---DPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNV 206 Q D + A PA+ SD S D+ AY+ YTSG+TG PK V VTH + Sbjct: 7142 VPWLQLDSPKFEKACQSKPALPVADSDRRSPISLDNAAYIVYTSGSTGKPKGVVVTHEGL 7201 Query: 207 TQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHN 266 + + + FD SV+E A G +V+ P +V + L Sbjct: 7202 DNFAEDQRQRFAAAQTSRTLHFSTPSFDGSVFEYLQAFGVGATMVIAPPTVYGGAE-LAE 7260 Query: 267 LLITEKVSVLCQTPSAAGMLSPEGLESTTLIV-AGEACPTELVDRWAPGRVMINAYGPTE 325 L+ +E V+ T +A + P GL+ +V GEACP ELV RWAPGR + NAYGPTE Sbjct: 7261 LIRSEHVTHAFVTTAALSTVDPTGLDEFQHVVFGGEACPPELVTRWAPGRQLSNAYGPTE 7320 Query: 326 ATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIG 385 T+ A +S+P+ L VLD L+P P GV GELY+ G G+A GY Sbjct: 7321 TTVMANISDPMTVGDPITLGGPIRGVGEL-VLDSRLQPVPVGVPGELYITGAGLARGYHR 7379 Query: 386 RPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQA 445 RP+L++ RFVA PFGE GERMYRTGD+VRW +D +EY+GR+D QVKIRG+RIELGEI Sbjct: 7380 RPELSSQRFVANPFGEAGERMYRTGDIVRWRADHTVEYVGRSDFQVKIRGFRIELGEIDN 7439 Query: 446 ALAKLDGVDQAVVIAREDRPGDKRLVGYI----TGTADPAQLRTALAESLPAYMVPTAVV 501 +A GV A + GD LV Y+ G DPA+L L+ LPA+MVPT+V+ Sbjct: 7440 EIATFPGVSFAATLGVPGPSGDTVLVTYLLPNTAGGVDPAELTAHLSTRLPAHMVPTSVM 7499 Query: 502 VLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSF 561 LD IPLT GKLDR ALPAPE+ +++ P+ E+ + D++A VLG+ER+G+DD+F Sbjct: 7500 FLDEIPLTPVGKLDRSALPAPEFHVTTTEFQPPTNDLERKIVDIFADVLGIERIGIDDNF 7559 Query: 562 FDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVVDEGVGPVVA 621 FDLGG+S+++ +V AR R A DI V + V G P +A Sbjct: 7560 FDLGGNSLVATRVTARLRDA----LDTDIGVRALFEAPDVRSLAARVADSVSGGARPALA 7615 Query: 622 TPIMR--------------WLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHA 667 P+ R +L + D + +N + + + ED + + + +L+RH Sbjct: 7616 -PVERPDRIPLSLAQKRMWFLNQFDTSSPAYNIPLAVRLTGTLDEDALRLAMADVLERHE 7674 Query: 668 TLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDALTDDV---LVEARNR-LDPAAGA 723 TLR D + ++P A A+ + TV +D+ +++ +R D + Sbjct: 7675 TLRTVFPTV--DNEPTQRILP---AADAQPGVDTVSVAAEDLPRHIMDLVSRGFDVSTDV 7729 Query: 724 MVSAVWVR---ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTG 767 V A R + L +++HH++ DG S L D+ +A+ G Sbjct: 7730 PVRAALFRIAPDHHVLTIVVHHISADGFSLAPLARDVMVAYTSRLGG 7776 Score = 428 bits (1101), Expect = e-117 Identities = 324/955 (33%), Positives = 463/955 (48%), Gaps = 82/955 (8%) Query: 14 DLLDEDE-HDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYREL 72 DL+ DE H +E W + V P T+ +LF QV R PDAVA+V + Y E Sbjct: 1767 DLIGADETHRMLEQWIDTDVAV---PDSATLVSLFEAQVARTPDAVAVVFAEEELLYAEF 1823 Query: 73 DEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGF 132 D +NRLA L G P + VA + RS E +++I +V KTGAAY+P+DP HP +RI + Sbjct: 1824 DARANRLARELLARGVGPESRVAVALRRSLELMIAIYAVEKTGAAYVPLDPDHPASRIAY 1883 Query: 133 MMSDAKPVAALTTADLRSRLDQYD----LAVIDMADPAIDRRPSDALS-----GP-RPDD 182 ++ A+P LT++ R R + D AVI++ + RRPS ++ GP PD Sbjct: 1884 VIESAEPACVLTSS--RDRCEGVDSAAGAAVIEIDTLNLSRRPSTPITAAERGGPIHPDS 1941 Query: 183 LAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWG 242 AY+ YTSG+TG PK VAV+H + + + V Q + FDVSVWE++ Sbjct: 1942 TAYVIYTSGSTGRPKGVAVSHRAIVNRLLWMQDTYRMDHTDVVLQKTPVTFDVSVWELFW 2001 Query: 243 ALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLS----PEGLESTTLIV 298 L G RLV+ P L +++ +V+ + PS + + PE S + Sbjct: 2002 PLEVGARLVLAAPDGHRDPTYLSHIIADHQVTTMHFVPSMLAVFTAGAEPELCGSLRQVF 2061 Query: 299 -AGEACPTELVDRWAP--GRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLF 355 +GEA P D + + N YGPTEA + E ++ Sbjct: 2062 CSGEALPPATADAFREFGSAALHNLYGPTEAAVDVTYWECTEGDRASVPIGAPVWNTQVY 2121 Query: 356 VLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRW 415 VLD L P P GV GELY+AG +A GY+GR DLT+ RFVA PFG G+RMYRTGD+VRW Sbjct: 2122 VLDSRLHPVPVGVHGELYLAGIQLARGYVGRSDLTSDRFVANPFGAPGQRMYRTGDVVRW 2181 Query: 416 GSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT 475 +DG +EY+GR D QVK+RG RIELGE++AA+ V QAVV + LVGY+ Sbjct: 2182 RADGNIEYIGRRDFQVKLRGQRIELGEVEAAVLAHPSVAQAVVTVHRSEATGESLVGYVI 2241 Query: 476 GTA----DPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDY 531 A D A +R A AE+LPAYMVPT ++VLD PL GKLDR ALP PE+ S + ++ Sbjct: 2242 PVAGADIDTAVVRDAAAEALPAYMVPTRIIVLDRFPLGATGKLDRGALPEPEFLSPSAEF 2301 Query: 532 RAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDI 590 P P E+ILA ++A +L R+GV DSFFDLGG+S+++ ++VAR AA G + R+I Sbjct: 2302 VTPRNPIEEILASIFADLLDAPRIGVYDSFFDLGGNSLVATRLVARVNAALGSRIGVREI 2361 Query: 591 FVEQTXXXXXXXXXXXXESHVVDEGVGP-------------VVATPIMRWLREVDGPTGQ 637 F T ES V P +A M ++ + D + Sbjct: 2362 FDAPT----VATLATRIESEAVQGAERPPLVAGARPDRLPVSLAQKRMWFINQFDLDSPA 2417 Query: 638 FNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARE 697 +N + + + ED + + ++DRH +LR R + + + +++P V Sbjct: 2418 YNIALAVRLTGDLDEDAMQDAVADVMDRHESLRTRFPMVEGEPVQ--VILPTEDVVPDLS 2475 Query: 698 CLRTVDA-LTDDVLVEARNRLDPAAGAMVSAVWVRE---TSQLVLMIHHLAVDGVSWRIL 753 + T +A L + + A D V A R LV+++HH++ DG S L Sbjct: 2476 PIATTEAELPEHISRLAGAGFDVTVSVPVRAALFRTDPGEHVLVIVVHHISADGFSMAPL 2535 Query: 754 LEDLNIAWAQHCTGQSIE---LPAGGTSFARWSALLAEHA--KTDTVRDLADAW-RAVTS 807 D+ A+A GQ+ + LP FA W + +A + D W + Sbjct: 2536 ARDVMTAYAARTGGQAPDWTPLPVQYADFALWQHRVLGNADDPDSLLAAQLDYWTHTLAG 2595 Query: 808 VPQ--ALPPVQP-DTDTYVTAGQLSASLD-------VETTRQLLGEVPAAFRAGVQDILL 857 +P+ ALP P T + G S S+D + T R+ V A A + +LL Sbjct: 2596 LPELLALPTDHPRPTQQSMRGGIHSFSIDPQVHSRLITTAREHNSSVFMAVHAALA-VLL 2654 Query: 858 VAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTVE 912 G + D +G + G G D L VG F + VE Sbjct: 2655 ARLG-------DTDDVSVGTPIAGRG-------DAALDDMVGMFVNTLVLRTPVE 2695 Score = 421 bits (1082), Expect = e-115 Identities = 261/589 (44%), Positives = 336/589 (57%), Gaps = 22/589 (3%) Query: 1 MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVAL 60 +TA+P R + + LLDE E +++ + P P P L PD+VAL Sbjct: 8050 VTADPD-RPIGTLPLLDEAEIEEMVPARGK-----PDVRPEVWPDLLTAAAALDPDSVAL 8103 Query: 61 VSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLP 120 DR TYRELDE SNRLA VL G P VA +PRS E ++SI SV K+GAA++P Sbjct: 8104 SFEDRQVTYRELDEWSNRLARVLCAQGVGPETFVAIGMPRSIEEVVSIWSVAKSGAAFVP 8163 Query: 121 VDPAHPDARIGFMMSDAKPVAALTTADLRSRL-DQYDLAVIDMAD-----PAIDRRPSDA 174 VDP +P RI +M++D + LT A R L D V+D A+ P Sbjct: 8164 VDPTYPRDRIDYMLTDCRASVGLTVAGRRDNLPDTVPWLVLDDESFAEQVAAVSSSPVTD 8223 Query: 175 LSGPRPDDLA---YMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSL 231 RP LA Y+ YTSG+TG PK V VTH + L + H S S Sbjct: 8224 ADRTRPLHLAHPAYLIYTSGSTGKPKGVIVTHRGMANLTAEEHERFQVTHESRVSHLASP 8283 Query: 232 VFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGL 291 FD S++E+ A R+V+VP +V + L +L V+ TP+A + GL Sbjct: 8284 SFDASIFELMMAFGASARVVIVPPTVFGGTE-LADLFRRNAVTHAFITPTALSSIEDVGL 8342 Query: 292 EST-TLIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXX 350 ES L VAGEACP ELV+ W R M N YGPTE TI A++S P+ Sbjct: 8343 ESLRVLAVAGEACPPELVEIWGKHRNMHNGYGPTETTIQASVSAPMRPGGVVNIGAPALG 8402 Query: 351 XXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTG 410 L VLD+ L+P P GV GELY+ G G+A GY R LT+ RFVACPFGE G RMYRTG Sbjct: 8403 FGSL-VLDERLQPVPVGVPGELYITGPGLARGYHNRSALTSERFVACPFGEPGRRMYRTG 8461 Query: 411 DLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRL 470 D+VRW D +EY+GR D QVK+RG+RIELGEI A LA+ V A I GD L Sbjct: 8462 DVVRWRGDHTIEYIGRTDFQVKVRGFRIELGEIDAVLARHPAVAFAATIGHTGPSGDTLL 8521 Query: 471 VGYITGT----ADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRS 526 Y+ +PA+LRT A+ LPA+MVP+AVVVLD IP+T GKLDR+ALPAPE+ + Sbjct: 8522 ASYVRAAEGHDLEPAELRTHAADRLPAHMVPSAVVVLDQIPMTPVGKLDRKALPAPEFGT 8581 Query: 527 AANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVV 575 +RAP+T E+I+ + +A+VLGV+RVG DSFFDLGG+SI++ +V+ Sbjct: 8582 TGAAFRAPTTATERIIVEAFAEVLGVDRVGTADSFFDLGGNSIVATRVI 8630 Score = 77.4 bits (189), Expect = 3e-11 Identities = 86/336 (25%), Positives = 131/336 (38%), Gaps = 24/336 (7%) Query: 1094 PLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFV 1153 PL+ VQ+ + F + + + I + G +D L DA + R + Sbjct: 24 PLSSVQRSMWFAQQLSPTVPKFIAQY---IELRGEIDLDLLSDAAVRAGQEFQSPFLRLL 80 Query: 1154 EQFGEPVQVL--TADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAAL 1211 + GEP Q + + DP I +LD RG+ + Q+ E A L R Sbjct: 81 DVDGEPYQAVDFSIDPSIG--FLDFRGE--SDPMGAAQVWIDEDYATPLRLTRDRLVEMT 136 Query: 1212 IRTSGNQHRFVLT-FHHIVIDGWSLPILLQEIFAGYFG----------HRLPAAAPYRNF 1260 + G QH T HH+ +DG+S ++ I A Y L Y Sbjct: 137 VLQVGEQHYLWYTRIHHVALDGYSGMTMVNRIAALYTAAVEGTEPEPNRALDLRDLYELD 196 Query: 1261 VNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRG--IESYRVSAETTRALGELAR 1318 + W E + G E + +A P +ES ++S LGE + Sbjct: 197 QKYRASSRFENDRLYWAERIVGIEHGSTLATHDAPAAAKSRLESAKISDTALGFLGESDQ 256 Query: 1319 SQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKV 1378 T VL A + L RMTG+RDV VS R A + G+L+N P+R V Sbjct: 257 RVGATSAAVLLAGFACYLSRMTGKRDVLINLPVSARTT--APLQRSGGMLVNVAPLRITV 314 Query: 1379 SADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSG 1414 + TV +L+++ Q L H+ +L DI +G Sbjct: 315 RPEDTVAELVQRTQLELMGALRHQRCSLEDIRRDAG 350 >tr|D5PTH5|D5PTH5_COREQ Tax_Id=525370 SubName: Full=Non-ribosomal peptide synthetase;[Rhodococcus equi ATCC 33707] Length = 8139 Score = 1328 bits (3438), Expect = 0.0 Identities = 868/2140 (40%), Positives = 1145/2140 (53%), Gaps = 106/2140 (4%) Query: 36 PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA 95 P P T+P L + R P AL TY ELD S+ LA L + G PGA VA Sbjct: 2094 PAIEPHTLPDLLSAAADRDPRRPALRFEGADVTYGELDRISDELARTLIDEGIGPGAVVA 2153 Query: 96 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLR-SRLDQ 154 +PRS ++ + +V K+GAA+LPVDPAHP RI M+ D+ LTTA+LR S +D Sbjct: 2154 LGMPRSLGYLVGVWAVAKSGAAFLPVDPAHPPDRIELMLRDSGAALGLTTAELRDSFVDI 2213 Query: 155 YDLAVID-----MADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNVTQL 209 +D DP R + + R DD+AY+ YTSG+TGVPK VAVTH + Sbjct: 2214 VPWRAVDENAFAAIDPTGSIRDDERTAPLRVDDVAYLIYTSGSTGVPKGVAVTHRGLANF 2273 Query: 210 VSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHNLLI 269 + LH + P Q S FDVSV E+ A+ G LV+ P +V ++L LL Sbjct: 2274 AADLHERCGTAPDSRILQLTSPSFDVSVLELLLAVGVGATLVIAPPTVYGG-EELRRLLA 2332 Query: 270 TEKVSVLCQTPSAAGMLSPEGLES---------TTLIVAGEACPTELVDRWAPGRVMINA 320 +E+V+ TP+A M +P G +S T ++ AGEA P ++V RWA GR MI+A Sbjct: 2333 SEQVTHCIMTPTALAM-TPTGADSDGAAELDRLTCVLAAGEALPPDVVARWARGRTMIDA 2391 Query: 321 YGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVA 380 YGPTE T+ S L L VLD L+P P G GELY+AG G+A Sbjct: 2392 YGPTETTVIGTASAGLEPGDAVTIGGPIRGFHAL-VLDDRLQPVPVGTPGELYLAGPGLA 2450 Query: 381 TGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIEL 440 GY RP LT++RFVA P GE GERMYRTGD VRW G LEY GR D QVK+ G+RIEL Sbjct: 2451 RGYHRRPALTSARFVADPSGEPGERMYRTGDRVRWTDVGTLEYFGRGDRQVKLHGHRIEL 2510 Query: 441 GEIQAALAKLDGVDQAVVIARE-DRPGDKRLVGYITGTA----DPAQLRTALAESLPAYM 495 GEI+A L + V V R R GD RLV Y+ A D A+L +A LP+YM Sbjct: 2511 GEIEAVLTQHPAVAHVVADVRGVGRLGD-RLVAYVVPAAGADVDTARLHDIVAARLPSYM 2569 Query: 496 VPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERV 555 VP + VL IP+TV+GKLDR ALP P + + R P+TPAE L V+A VLG+E V Sbjct: 2570 VPRHITVLARIPMTVHGKLDRAALPEPAVGAEVSATRPPATPAETALVRVFADVLGLETV 2629 Query: 556 GVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXE-----SH 610 GV+DSFFDLGGDSI+S+Q+VARA+AAG+ PRD+F +T + Sbjct: 2630 GVEDSFFDLGGDSIMSIQLVARAKAAGLSVTPRDVFDRRTVAALAAVAMSDDAGGESLAE 2689 Query: 611 VVDEGVGPVVATPIMRWL-REVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATL 669 + GVG V TPI+ WL R G+F Q+V+ P GV E D++ QA+LDRH L Sbjct: 2690 LDGGGVGDVPLTPILAWLVRRAGRRIGRFAQSVLLNLPDGVRESDLLAAAQAVLDRHDML 2749 Query: 670 RLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA---------LTDDVLVEARNRLDPA 720 R R++ D W V GAV AR+ + L + L + +RLDPA Sbjct: 2750 RARLD---HDESGWRTEVLPIGAVDARDLVSRYPVRDFEDGFARLAEAELQASADRLDPA 2806 Query: 721 AGAMVSAVWVRE---TSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGT 777 AG+M+ VW + +L++++HH VDGVSWR+++ DL AWAQ G+ EL GT Sbjct: 2807 AGSMIRLVWFDGPDGSGRLLVVVHHTVVDGVSWRVIVPDLAAAWAQSVDGRRPELDPVGT 2866 Query: 778 SFARWSALLAEHAKTDTVRDLADA---WRAVTSVPQALPPV-----QPDTDTYVTAGQLS 829 S RW+ +A DTV D + W V V A PP+ PD D + T + Sbjct: 2867 SMRRWA-----YALRDTVSDRMNELSLWEDV--VGGADPPIGRRHPDPDRDVHATTDTVL 2919 Query: 830 ASLDVETTRQLLGEVPAAFRAGVQDILLVAFGLA---WTEFLNRSDTPIGVDVEGHGRYD 886 V T LL +P A QD+LL A LA WT D + + VEGHGR + Sbjct: 2920 VDAPVSDTALLLTSLPTAIHGSAQDVLLAALALAVARWTTLRGPGDDAVLLGVEGHGREE 2979 Query: 887 ELASDVDLSRTVGWFTTKYPVALTVENLPWEQVVAGDAALGGIVKAVKEQLRSLPE-GLT 945 + DLSRTVGWFTT +PV + + + AG A G VK VKE LRS P G+ Sbjct: 2980 DAVPGADLSRTVGWFTTIHPVRPDLSGIDLDDAWAGGPAAGAAVKLVKEHLRSAPHHGIG 3039 Query: 946 YGLLRYLNPEVDLG-GSDPTIGFNYLGRLGAGAGELSEE-LWRIDQXXXXXXXXXXXVPM 1003 YG+L L+ + S P I NYLGRL G S W Q M Sbjct: 3040 YGMLTELDGDAGRRLRSSPQIMLNYLGRLTVADGPASGPGPWMPVQAGGLGLTQDPD--M 3097 Query: 1004 PLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQATRLSRLWFEALAGICAHVRG-GG 1062 P+ ++++AG +G +L+ASWT+ D +L+ LW EAL G+ + R G Sbjct: 3098 PVSAALDISAGVRARPDGGALQASWTYPTGVLDRADVQQLAELWLEALHGLAGYARTPGA 3157 Query: 1063 GGLTPSDVAPARLTQRQIDEL-SQRYDVTDVLPLTPVQQGLLFHSTFARGIGD-DVYAVQ 1120 GGLTPSD+ L Q ID L + R + DV P+TP+Q GLLFH+ A D D Y +Q Sbjct: 3158 GGLTPSDLDLVELDQSGIDALEATRPRLADVWPVTPLQAGLLFHAHLAEDAPDTDAYLIQ 3217 Query: 1121 LDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFG-EPVQVLTADPMIAWRYLDLRGD 1179 L I + G + RLRDA +++ R+PNL A FV+ G E +QV+ + + WR +DL G+ Sbjct: 3218 LVIELRGEPARERLRDAARSLLDRYPNLRAGFVDDAGGETIQVIESGVTVPWREVDLSGE 3277 Query: 1180 DLTPDHEIEQLCAAERSAVCDLLERPTF-RAALIRTSGNQHRFVLTFHHIVIDGWSLPIL 1238 Q AAE A ++RP R L+R +R +LT HHI++DGWS P+L Sbjct: 3278 TPADVESRWQALAAEDRATPFAMDRPPLLRFTLVRVGHGSYRLLLTHHHILLDGWSTPLL 3337 Query: 1239 LQEIFAGYFGH---RLP-AAAPYRNFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGV 1294 LQ + Y P A YR+++ WL W LDG PTL+A P Sbjct: 3338 LQRLLMQYAAEPDVTAPFPAGDYRDYLAWLATRDRDASVAAWCRALDGVADPTLLAAPDA 3397 Query: 1295 PGPRGIES---YRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAV 1351 P G +S T AL +AR T NTV+Q AW +L +TG+ DV FG V Sbjct: 3398 PETAGASDDLDLVLSDSDTAALTRVARDHGVTPNTVVQVAWALVLGVLTGRTDVVFGATV 3457 Query: 1352 SGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHH 1411 SGR AD+ G ESM+GLL+NTVP+R + + TVG+LLR++Q +EH +AL D+ Sbjct: 3458 SGRHADVPGIESMIGLLVNTVPVRVRTDSRETVGELLRRVQREQAALMEHHDVALADVQQ 3517 Query: 1412 VSGHEQLFDTLFLYESYPIDTSAF---MGVQELAVTEFNNREYNHYPLSVMALPGHELGL 1468 +G +FDTL ++ESYPID S + L+VT + HYP+++ A L L Sbjct: 3518 AAGPGAVFDTLTVFESYPIDRSGLERGADIAGLSVTAVRGIDATHYPVTLRAALTDRLHL 3577 Query: 1469 RVEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLT 1528 V+Y + V D ++ E L R Q L+ + R ++ +D+ ER EW Sbjct: 3578 TVKYRSGVVDRADAELLRARVQAALDVVTHHHDRTIARVDLSTPAERK---EWLPSG--- 3631 Query: 1529 QPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSV 1588 P +P +P++ A +P+ AVT SL Y ELDE +N+LA L GA PG V Sbjct: 3632 GPAAAPALLPQLLASGAVANPDGLAVTAADGSLTYRELDERSNRLARSLVRAGAGPGAVV 3691 Query: 1589 ALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDG 1648 A +PRSA ++ A+ AV K+GAA+LP+DP+ P R+E ML DA VT+ R Sbjct: 3692 ACALPRSAVSVQAMWAVAKSGAAFLPVDPAYPRERIENMLADADVGVGVTSAADRRHLPD 3751 Query: 1649 FDLQVVEVDDPA-VEIYPSTTLLTPSP-------DDIAYMIYTSGTTGVPKGVAITHGNV 1700 ++ + +DDPA V ST +T DD+AY+IYTSG+TG PKGVA+TH + Sbjct: 3752 -TVRWILLDDPATVGGGESTDAVTDRDRTAPIHVDDVAYLIYTSGSTGRPKGVAVTHRGL 3810 Query: 1701 TQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHA 1760 T ++D + + P A S FD +V E+ A G LV+ P + G L Sbjct: 3811 TSLVDEMHSRYPISQDARCLHVCSPSFDFAVLELLQAGAVGAALVVAPPDVYGGAA-LAD 3869 Query: 1761 LLVSEGVNVLYQTPSAVRMMSPEGLEGTA-LVVAGEACPTEVVDRWAVDRVMINAYGPTE 1819 LLV++ + + TP+A+ + P + A LVV G+A TE+V WA R MI+ YGP E Sbjct: 3870 LLVAQQITHMCITPAALATVEPGRFDDLAVLVVGGDAVGTELVAGWATGRTMIDGYGPAE 3929 Query: 1820 STIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXX 1879 STI SAPL PG+DV PIG+PV VLDE+LRPVPPGV GELY+ Sbjct: 3930 STIVTTFSAPLVPGADV-PIGTPVRGTGVLVLDEYLRPVPPGVPGELYVVGAGLARGYHR 3988 Query: 1880 XXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQA 1939 LT RFVACP G GARMYRTGD+VR DG L YLGR+D QVK+RG RIELGEI+A Sbjct: 3989 RPGLTAARFVACPRGAAGARMYRTGDIVRRRPDGALDYLGRSDFQVKVRGLRIELGEIEA 4048 Query: 1940 ALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAAARSELT----NRLPAYMVPAAVV 1995 L V +V +AR GD L Y+ D +ELT RLP +M+P A+V Sbjct: 4049 VLVAHPAVAHSVTVARRRGAGDSLLASYVVPATDDGIDVTELTEFAARRLPRHMLPNAIV 4108 Query: 1996 TLETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXX 2054 L LP+T GKLDR ALP P++ + YRAP T EK + +FA + G +R Sbjct: 4109 VLGELPVTPVGKLDRDALPEPDFGRPTAPYRAPRTPAEKQVVAVFAEITGADRVGLDDNF 4168 Query: 2055 XXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 A RV A +N AL + L VR LFE T +L+ Sbjct: 4169 FGLGGNSLGATRVVARINRALGSGLDVRDLFECGTAGRLA 4208 Score = 1270 bits (3287), Expect = 0.0 Identities = 814/2183 (37%), Positives = 1140/2183 (52%), Gaps = 136/2183 (6%) Query: 31 AVLTDPG-----------PTPVTIPA--------LFAEQVVRAPDAVALVSGDRSWTYRE 71 AV DPG P PV +P LF PDAVA+V GD TYR+ Sbjct: 4658 AVAGDPGIAVGDVGLIDAPAPVAVPVTAEGTLADLFGAAAAADPDAVAVVCGDERITYRD 4717 Query: 72 LDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIG 131 LD SNRLA L E G P + VA + R+ + + ++ +++ GAAYLPVDP +P RIG Sbjct: 4718 LDAHSNRLARWLIERGIGPESVVAVAMERTVDLVAALAGIVRAGAAYLPVDPGYPPERIG 4777 Query: 132 FMMSDAKPVAALTTADLRSRLDQYDLA----VIDMADPAIDRRPSDALSGP--------- 178 F++ DA LT A + L L ++ + + +R SGP Sbjct: 4778 FVVRDAGARTLLTDAGSAAGLSDVPLPEHTEIVGLDAEDVRQRIEGRPSGPVADHERVRR 4837 Query: 179 -RPDDLAYMTYTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSV 237 PD AY+ YTSG+TG PK V VTH NV L+S + VW+ +HS FD +V Sbjct: 4838 LHPDSPAYVIYTSGSTGRPKGVVVTHRNVVTLLSGARDVIGFDASDVWTLFHSYAFDFAV 4897 Query: 238 WEIWGALLHGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGML------SPEGL 291 WE+WGAL GGR+VVV +PDDL LL E V++L QTPSA G L S L Sbjct: 4898 WELWGALGFGGRVVVVDRHTARAPDDLVALLAAESVTLLSQTPSAFGQLARAEADSDRPL 4957 Query: 292 ESTTLIVAGEACPTELVDRWAPGR-----VMINAYGPTEATIYA-----AMSEPLXXXXX 341 ++ GEA + WA R +IN YG TE ++ A +E Sbjct: 4958 ALRRVVFGGEALDATRLADWAARRGADRPALINMYGITETCVHVTWHPVAAAEVDSSRTV 5017 Query: 342 XXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGE 401 + VLD L P P GVVGELYVAG VA GY+ RPDLTASRFV P Sbjct: 5018 GSVIGVGLPGIGVRVLDDRLHPVPVGVVGELYVAGPQVARGYLHRPDLTASRFVPDPCAP 5077 Query: 402 TGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAR 461 + RMYR+GD VRW G LEY+GRAD QV++RG+R+E GE++AAL + GV AVV+AR Sbjct: 5078 S-RRMYRSGDRVRWTRSGDLEYIGRADFQVQVRGFRVEPGEVEAALTAVPGVAAAVVLAR 5136 Query: 462 EDRPGDKRLVGYITGTADPAQLRTA------LAESLPAYMVPTAVVVLDTIPLTVNGKLD 515 + G RL+GY+ +P Q TA + + LP+YMVP+ V VL PLT NGK+D Sbjct: 5137 AESAGADRLLGYVV--PEPGQTVTAETVTDAVGQRLPSYMVPSTVTVLGEFPLTSNGKID 5194 Query: 516 RRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVV 575 R ALP P R + R P+T E+IL D++A VLG E VGVDDSFF LGGDSI+S+Q+V Sbjct: 5195 RAALPDP--RPVGGEGRPPATDVERILTDLFADVLGAESVGVDDSFFGLGGDSIMSIQLV 5252 Query: 576 ARARAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHVV------DEGVGPVVATPIMRWLR 629 +RA+AAG+ PRD+F +T V GVG V TP++ WL Sbjct: 5253 SRAKAAGVTITPRDVFECRTVARLADVAAQLDRPRVELLPELPGGGVGDVATTPVVHWLA 5312 Query: 630 EVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPE 689 E G ++ Q+++ P + D + + A+LDRH LR ++ L V Sbjct: 5313 ERSGDFHRYAQSLVLDVPVDLDPDTLATAVDAVLDRHDMLRAQLRHDDRSRTGRRLTVRP 5372 Query: 690 AGAVGARECLRTV-------DALTDDVLV---EARNRLDPAAGAMVSAVWVRET--SQLV 737 GAV R +RTV A T+ V EA +RLDP +G+++ V + + ++LV Sbjct: 5373 PGAVDGRSVMRTVAVPTVQGSAFTEAARVALEEAADRLDPFSGSIIQIVRLTASDGARLV 5432 Query: 738 LMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKTDTVRD 797 +++HHLAVDGVSWRIL+ DL A+ G+ +L GTS W+ L A+ D V + Sbjct: 5433 VVVHHLAVDGVSWRILIPDLVAAYTGAVAGRDPDLAPVGTSMRTWADGLVTAAQ-DRVDE 5491 Query: 798 LADAWRAVTSV---PQALPPVQPDTDTYVTAGQLSASLDVETTRQLLGEVPAAFRAGVQD 854 L + WR++T A + P+ D T ++ +L E TR L VP F V D Sbjct: 5492 L-ELWRSMTEPVGPSLAARQLDPNVDVGATTDRVEIALSAEVTRALTTTVPRVFHGSVDD 5550 Query: 855 ILLVAFGLA---WTEFLNRSDTPIGVDVEGHGRYDELASDVDLSRTVGWFTTKYPVALTV 911 L+ A LA W + V +EGHGR D + DLSRTVGWFTT +PV + Sbjct: 5551 GLVSALALAVAQWRRERGVDVDAVAVTLEGHGREDHVVPGADLSRTVGWFTTFHPVRFDL 5610 Query: 912 ENLPWEQVVAGDAALGGIVKAVKEQLRSLPE-GLTYGLLRYLNPE---VDLGGSDPTIGF 967 + + G A +VKAVKE +RS+P+ G+ +GLLRYLN E V P I F Sbjct: 5611 SDTDLDAATTGGPASDTVVKAVKETMRSIPDHGIGFGLLRYLNDETRPVLSARPVPEISF 5670 Query: 968 NYLGRLGAGAGELSEELWRIDQXXXXXXXXXXXVPMPLMHTVELNAGTIDTDNGPSLRAS 1027 NYLGR GAG W + + P + V++NA + +GP + A+ Sbjct: 5671 NYLGRFDTGAGGA----WLPVEDAELRGVATPELSAPAV--VDVNAAAVSGPDGPRITAT 5724 Query: 1028 WTWAPSAFDEEQATRLSRLWFEALAGICAHV-RGGGGGLTPSDVAPARLTQRQIDELSQR 1086 W + + + RL++ W A I G GG TP+D+ L Q I+ L R Sbjct: 5725 WDFPRGLLNRGEVERLAQWWERAAEAIARRAGTPGAGGFTPTDLDLVALDQGAIEVLEDR 5784 Query: 1087 Y-DVTDVLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARH 1145 Y +++DV PL+P+Q+G++F S + D Y VQL + + G ++ RL+ A H ++ RH Sbjct: 5785 YPELSDVWPLSPMQRGMMFQSELSADAAD-AYLVQLVLELDGAVEVPRLQRAAHALLGRH 5843 Query: 1146 PNLAARFVEQ-FGEPVQVLTADPMIAWRYLDLRGDDLTPDH--EIEQLCAAERSAVCDLL 1202 NL FV G+ VQV+ + W +DLR + P+ + +L +R+ DL Sbjct: 5844 ANLRTAFVRTPGGDAVQVVQGAVDVPWSEIDLR-EHSEPEAAARMRELLDTDRATAFDLS 5902 Query: 1203 ERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAA----APYR 1258 P R L+ G R V+T HHI+ DGWS P+LL+++FA Y P+ YR Sbjct: 5903 HAPLLRITLVHMPGGAERLVVTNHHILFDGWSTPLLLEDLFALYAADGDPSGLSTPTSYR 5962 Query: 1259 NFVNWLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIES----YRVSAETTRALG 1314 +++WL W + + G PTL+A R +ES +R+ A+ T L Sbjct: 5963 RYLHWLTTRDDSVTLRAWTDAIAGAAEPTLLADRSAATGRYVESRDLPFRLDADLTARLR 6022 Query: 1315 ELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPI 1374 A+ + T++TV+Q AW +L +TG+ DV FG VSGRP DLAG E+ VGL INTVP+ Sbjct: 6023 VRAQDRGITLSTVVQTAWGIVLGLLTGRDDVVFGATVSGRPPDLAGVETAVGLFINTVPV 6082 Query: 1375 RAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESYPIDTSA 1434 R ++ ++GDLL ++Q+ L+H H L + +G +FDTL ++ESYP+ + Sbjct: 6083 RIRLDPYESLGDLLARIQTEQTAMLDHHHAGLEAVQRAAGPGAVFDTLTVFESYPLRDAD 6142 Query: 1435 FMGVQ--ELAVTEFNNREYNHYPLSVMALPGHELGLRVEYDTSVFDVSEIETLIDRFQRL 1492 G + L V + R+ HYPLSV+A L + +++ V SE+ + R R+ Sbjct: 6143 GSGTEIAGLRVVGIDARDSAHYPLSVVAAVRDGLNVTMKFRPDVLPESEVAAIAQRLLRV 6202 Query: 1493 LEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAP 1552 L + D+P RR++++D + + E L + T P +P+++ + RD EA Sbjct: 6203 LRFLADEPDRRVAALDFLSEAEHRALVP-----MRTGPGAAPRTLAAILDAAAARDGEAL 6257 Query: 1553 AVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAY 1612 A+ +G + YG+LD +N+LA L+ G P V L + RS ++++A+ AV ++GAA+ Sbjct: 6258 ALVGDGREVTYGDLDRRSNRLARHLSHLGIGPESMVVLGIARSFESVLAVWAVARSGAAF 6317 Query: 1613 LPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDP----AVEIYPSTT 1668 +PIDP P R+ ML D+ VTT + RSR LQ + +DDP A E +P+ Sbjct: 6318 VPIDPDYPPERVATMLADSGATVGVTTREHRSRLPD-TLQWLVLDDPGFERAYETWPADA 6376 Query: 1669 LLTPSP------DDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQW 1722 + D++AY+IYTSG+TG PK V++TH + D P A + Sbjct: 6377 VSDADRTAPLLLDNVAYLIYTSGSTGRPKAVSVTHRGLGNYADVQRDRCGLSPDARTLHF 6436 Query: 1723 HSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMMSP 1782 S FDVSV E G +VIVP ++ G +L A+L V + TP+A+ + P Sbjct: 6437 SSPSFDVSVVEYLLCFAVGATMVIVPRTVYGG-SELTAVLRKRRVTHAFITPAALASVDP 6495 Query: 1783 EGLEGTALV-VAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDVVPIGS 1841 GL+ V V GE+ E+V+ W ++NAYGPTE+T+ + + +G Sbjct: 6496 SGLDDLECVLVGGESWSPELVEDWLPQCRILNAYGPTETTMVVNLEESAADRPAEHSLGP 6555 Query: 1842 PVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMY 1901 P+P VLD LRPVP G+ G++Y+A LT RFVA P+G PG RMY Sbjct: 6556 PIPGVTETVLDSCLRPVPAGIAGDVYIAGPGLARGYHRRPGLTAARFVADPYGAPGDRMY 6615 Query: 1902 RTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGD 1961 RTGD+ W DG+L+Y GR+D QVK+RG+RIELGEI A L+ V A + R GD Sbjct: 6616 RTGDVGAWRPDGKLEYRGRSDFQVKVRGFRIELGEIDAVLTGHPDVRFAATLGRRGPAGD 6675 Query: 1962 KRLVGYITGT----ADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPE 2017 LV Y+ R L R+P YMVP A V L+ +PLT GKLDRRALP PE Sbjct: 6676 TMLVSYVVARDGHHVHVDELRRHLAERVPEYMVPTATVVLDDIPLTPVGKLDRRALPEPE 6735 Query: 2018 Y-QSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALD 2076 + +A ++AP E+ + G FA VLG+ R A R A ++ +L Sbjct: 6736 FGLAATTFQAPTDPVEEAITGAFAEVLGLGRVGTGDNFFDLGGNSLSATRAVARLDASLG 6795 Query: 2077 ADLSVRTLFEAPTVAKLSLHVEH 2099 DL VR LFEAPT A L+ +EH Sbjct: 6796 VDLGVRALFEAPTAAALAERIEH 6818 Score = 479 bits (1234), Expect = e-132 Identities = 362/1087 (33%), Positives = 514/1087 (47%), Gaps = 83/1087 (7%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+P QQ + F + F Y + L + ++G+LD+ L +A+ VVARH +L + Sbjct: 1637 IPLSPAQQRIWFVNQF--DTDSAAYNISLSLKLSGLLDRDALDEAIGDVVARHESLRTVY 1694 Query: 1153 -VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAAL 1211 ++ G +VL D L + D+ + +++Q A S D+ + RA L Sbjct: 1695 PLDDAGPRQEVLPLDRT----GLGIDRADVDDEADLQQRMRALMSRGFDVSAQVPLRAGL 1750 Query: 1212 IRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGY-------FGHRLPAAAPYRNFVNWL 1264 R +H + HHI+ DG+SL +L +++ Y R P Y ++ W Sbjct: 1751 FRLGDTEHVLTVVLHHILADGFSLGVLARDLVTAYATRTASGVPSRTPRPVQYADYALWQ 1810 Query: 1265 --XXXXXXXXXXXWREVLDGFETPTLVAPPGV---------PGPRGIESYRVSAETTRAL 1313 LD + T TL P V P R + RV E L Sbjct: 1811 SEWLGDADDPASLLARQLD-YWTTTLADLPAVLDLPCDRARPDVRSQQGGRVEFELPAQL 1869 Query: 1314 G----ELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLI 1369 ELAR+ ++ V+ AA LL R+ G DV GT ++GR A A + MVG+ + Sbjct: 1870 HARIVELARAHDASVFMVMHAALAVLLARLGGTEDVTVGTPIAGRGA--AALDDMVGMFV 1927 Query: 1370 NTVPIRAKVSADTTVGDLLRQLQS------HHNDTLEHEHLALNDIHHVSGHEQLFDTLF 1423 NT+ +R V + +LL +++ H D + D + H LF L Sbjct: 1928 NTLVLRCAVGGSCSFAELLHRVREADLGAFMHADAPFERVVDAVDPPRSTTHSPLFQVLL 1987 Query: 1424 LYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMA-----LPGHELGLR--VEYDTSV 1476 + + GV+ V ++ + ++ L V G G+ + + T + Sbjct: 1988 EFRTIARPDVQLPGVRVRTVE--SDYDIANFDLQVSVAEEFDTDGAAAGMTAGIVFATDI 2045 Query: 1477 FDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQS 1536 FD + DR R+L+A+ + +++++ E L V P P + Sbjct: 2046 FDARTVRGFADRLLRILQAVTASADTAVGDIELLEPAEHAVL-----APVRGLPAIEPHT 2100 Query: 1537 IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSA 1596 +P++ + +RDP PA+ FEG + YGELD +++LA L G PG VAL +PRS Sbjct: 2101 LPDLLSAAADRDPRRPALRFEGADVTYGELDRISDELARTLIDEGIGPGAVVALGMPRSL 2160 Query: 1597 DAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRF------DGFD 1650 +V + AV K+GAA+LP+DP+ P R+E ML D+ +TT +LR F D Sbjct: 2161 GYLVGVWAVAKSGAAFLPVDPAHPPDRIELMLRDSGAALGLTTAELRDSFVDIVPWRAVD 2220 Query: 1651 LQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAE 1710 DP I DD+AY+IYTSG+TGVPKGVA+TH + L Sbjct: 2221 ENAFAAIDPTGSIRDDERTAPLRVDDVAYLIYTSGSTGVPKGVAVTHRGLANFAADLHER 2280 Query: 1711 LPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVL 1770 P + Q S FDVSV E+ A+ G LVI P ++ G ++L LL SE V Sbjct: 2281 CGTAPDSRILQLTSPSFDVSVLELLLAVGVGATLVIAPPTVYGG-EELRRLLASEQVTHC 2339 Query: 1771 YQTPSAVRMMSPEGLEG---------TALVVAGEACPTEVVDRWAVDRVMINAYGPTEST 1821 TP+A+ M+P G + T ++ AGEA P +VV RWA R MI+AYGPTE+T Sbjct: 2340 IMTPTAL-AMTPTGADSDGAAELDRLTCVLAAGEALPPDVVARWARGRTMIDAYGPTETT 2398 Query: 1822 IYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXX 1881 + SA L PG D V IG P+ VLD+ L+PVP G GELYLA Sbjct: 2399 VIGTASAGLEPG-DAVTIGGPIRGFHALVLDDRLQPVPVGTPGELYLAGPGLARGYHRRP 2457 Query: 1882 XLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAAL 1941 LT RFVA P GEPG RMYRTGD VRW D G L+Y GR D QVK+ G+RIELGEI+A L Sbjct: 2458 ALTSARFVADPSGEPGERMYRTGDRVRWTDVGTLEYFGRGDRQVKLHGHRIELGEIEAVL 2517 Query: 1942 SDVDGVDQAVVIAR-EDRPGDKRLVGYITGTA----DPAAARSELTNRLPAYMVPAAVVT 1996 + V V R R GD RLV Y+ A D A + RLP+YMVP + Sbjct: 2518 TQHPAVAHVVADVRGVGRLGD-RLVAYVVPAAGADVDTARLHDIVAARLPSYMVPRHITV 2576 Query: 1997 LETLPLTVNGKLDRRALPAPEY-QSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXX 2055 L +P+TV+GKLDR ALP P R P T E L +FA VLG+E Sbjct: 2577 LARIPMTVHGKLDRAALPEPAVGAEVSATRPPATPAETALVRVFADVLGLETVGVEDSFF 2636 Query: 2056 XXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKL-SLHVEHDAGERTDRVSFAAVH 2114 ++++ A A ++ R +F+ TVA L ++ + DAG S A + Sbjct: 2637 DLGGDSIMSIQLVARAKAA-GLSVTPRDVFDRRTVAALAAVAMSDDAGGE----SLAELD 2691 Query: 2115 GSDVTEV 2121 G V +V Sbjct: 2692 GGGVGDV 2698 Score = 470 bits (1209), Expect = e-129 Identities = 356/1075 (33%), Positives = 497/1075 (46%), Gaps = 100/1075 (9%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+ QQ + F + F Y V + + +TG LD LR AV V+ RH L RF Sbjct: 6838 LPLSAAQQRMWFINQFDPS--SPAYNVPMAVRLTGALDSSALRAAVGDVLTRHEALRTRF 6895 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALI 1212 P+Q + + +DL ++ D E+ A + D+ ER L Sbjct: 6896 PVGAAGPIQDVRPAAEVT---IDLEPVAVSGDDELRVRTRAIIATGFDVTERVPVDGGLF 6952 Query: 1213 RTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRL-------PAAAPYRNFVNWL- 1264 + + H VL HHIVIDG SL L +++ Y P Y ++ W Sbjct: 6953 ELAPDLHVLVLVAHHIVIDGLSLGPLSRDLMQAYVARTAGRPPDWDPLPVQYADYTLWQR 7012 Query: 1265 --------XXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIE--------SYRVSAE 1308 W E L G P L+ P PR I+ + + Sbjct: 7013 ALLGDEDDPGSLRSRQLAYWTETLSG--APDLLGLPS-DRPRPIQQSFRGDRVEFALDPG 7069 Query: 1309 TTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLL 1368 R L AR +++ + AA LL R+ D+ GT V+GR + +VG+ Sbjct: 7070 LHRRLLTFARDHGSSLFMTIHAALAVLLARLGDTDDIVVGTPVAGRGE--RALDDLVGMF 7127 Query: 1369 INTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHEQLFDTLFLYESY 1428 + T+ +R +V A + +LL +++ H + + + E Sbjct: 7128 VGTLALRTRVDARRSFSELLESVRNVDLGAFAHADVPFERV--------------VEELD 7173 Query: 1429 PIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHELGLR------------------- 1469 P ++A+ + ++A+ EF N E LS + L G +G Sbjct: 7174 PARSTAYSPLFQVAL-EFQNDESAGVELSGLRLEGVSIGAGMVKEDLEFVLGERFDGVGE 7232 Query: 1470 -------VEYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWA 1522 V + T +FD ++ DRF R++EA DP R + + ++ E L Sbjct: 7233 PAGISGVVAFATDLFDRETVQGFADRFVRIVEAASSDPERPVGDLGILHPYELAGL---- 7288 Query: 1523 NRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGA 1582 P P +P++ A R+P+A AV +G L Y +LDE AN+LA L GA Sbjct: 7289 -APARGAPDAPPLLLPDLLA-SAARNPDALAVVCDGRELTYRQLDEGANRLARHLIAMGA 7346 Query: 1583 APGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDL 1642 P VAL + RS +++A+ AV +TGAA++P+DP+ PA R+ ML D VT Sbjct: 7347 GPEGYVALGLSRSVSSVLAVWAVARTGAAFVPVDPNYPAERIARMLADCGATVGVTVRSC 7406 Query: 1643 RSRFDGFDLQVVEVDDP----AVEIYPSTTLLTPS------PDDIAYMIYTSGTTGVPKG 1692 R R G V +DDP AV P+T + D AY+IYTSG+TG PKG Sbjct: 7407 RERVPG-SFDWVVLDDPDVAEAVAAEPATPISDADRRRPLRADHPAYLIYTSGSTGTPKG 7465 Query: 1693 VAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIA 1752 V +TH + + L P A + S FD SV+E AL G +V+VP I Sbjct: 7466 VVLTHRGLADLAAEERDRLLVTPTARTLHFASPSFDASVFETVMALSAGATMVVVPPDIY 7525 Query: 1753 GSPDDLHALLVSEGVNVLYQTPSAVRMMSPEGLEG-TALVVAGEACPTEVVDRWAVDRVM 1811 G + +L + GV + TP+ + + P GLE LVVAGE CP E+V RWA R M Sbjct: 7526 GG-TEFAEILATGGVTHGFVTPTTLASLDPVGLESLRTLVVAGEPCPPELVRRWAPGRTM 7584 Query: 1812 INAYGPTESTIYAAISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXX 1871 +NAYGPTE+TI A ISAP+SP V +G P+ VLD L PVP GVVGELY+A Sbjct: 7585 LNAYGPTETTIMANISAPMSPHRPVT-LGGPIRGVREVVLDSRLHPVPRGVVGELYVAGS 7643 Query: 1872 XXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYR 1931 T RFVA PFG G R+YRTGDLVRW D L+Y+GR+D QVK+RG+R Sbjct: 7644 ALARGYHRRPGTTAARFVADPFGAAGDRLYRTGDLVRWRTDDTLEYVGRSDFQVKVRGFR 7703 Query: 1932 IELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGT----ADPAAARSELTNRLPA 1987 IE GEI L+ GV AV +AR G+ L Y+ T DP R + LPA Sbjct: 7704 IEPGEIDTVLAAQPGVGFAVTLARRGPAGNMLLCSYVCPTVDAHVDPDEMRRAVARHLPA 7763 Query: 1988 YMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQR-YRAPETETEKTLAGIFAHVLGVE 2046 +MVP+AV L+ +PLT GKLDR ALP P + +A YR P+ E + FA VLGVE Sbjct: 7764 HMVPSAVTVLDRVPLTPTGKLDRDALPPPAFLAAPAVYREPQGPVETAVVDAFADVLGVE 7823 Query: 2047 RXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLSLHVEHDA 2101 R A + A ++ + +S++ LF PT A L+ +E A Sbjct: 7824 RIGMDDSFFDLGGTSLLATGLVADLSARMGTRVSLQALFLNPTPAGLARRLETSA 7878 Score = 449 bits (1156), Expect = e-123 Identities = 359/1091 (32%), Positives = 495/1091 (45%), Gaps = 109/1091 (9%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 LPL+P QQ + F + G VY + +T+TG LD LR A+ VV RH L F Sbjct: 563 LPLSPAQQRMWFVNQL--DTGSPVYNIAFAVTLTGQLDVAALRAAIGDVVERHEALRTVF 620 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGDDLTPD----HEIEQLCAAERSAVCDLLERPTFR 1208 P QV+ D+TP HE + D+ E P R Sbjct: 621 PVDAEGPQQVIVPAESAV--------PDVTPAAAERHEAREQIRRVSVVGFDVREEPPLR 672 Query: 1209 AALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLXXXX 1268 L R +H + HHI DG S+ L +++ Y R A P R W Sbjct: 673 VQLFRLGPEEHVLAVVVHHIAADGQSVSPLARDVMVAYAARR--AGGPPR----WTPLPV 726 Query: 1269 XXXXXXXWREVLDGFE--------------TPTLV-APPGVPGP-----------RGIE- 1301 W+ + G E T L PP + P RG Sbjct: 727 QYADYALWQRDMLGDERDGRSVAAHQLQYWTARLADLPPAIALPHDRPRSATMTTRGATV 786 Query: 1302 SYRVSAETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGA 1361 + V A+T R L +L R T+ VL AA+ LL R+ RDVA GT V+GR + Sbjct: 787 TLDVGADTHRRLLDLGRECDCTLFMVLHAAFAALLARLGAGRDVAIGTPVAGRT--VPEL 844 Query: 1362 ESMVGLLINTVPIRAKVSADTTVGDLLR-----QLQSHHNDTLEHEHLALNDIHHVSGHE 1416 + VG+ +NT+ +R V +T +LL L + N L E L S + Sbjct: 845 DESVGMFVNTLVLRTDVDPASTFVELLAGVRDIDLAALANADLPFERLVEELATDRSPAQ 904 Query: 1417 QLFDTLFLYESYPIDTSAFMGVQELAVTEFNNREYN-HYPLSV---MALPGHELGLRV-- 1470 + L + T+ + V E + LSV + GH GL + Sbjct: 905 APLVQVLLELQTAVTTAVELPGVVADVREIDTGVAKFELQLSVREQVDRDGHPQGLSLAL 964 Query: 1471 EYDTSVFDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQP 1530 + +F+ + I R R+L+A+ D + +++ D ER A+ T P Sbjct: 965 HFARDLFEHATITGAARRLHRILDAIAADGDVVVGDLEITDAPER---------ALSTLP 1015 Query: 1531 VDS---PQSIPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKS 1587 D+ P ++P++ AR V PEA AV L Y EL + N+L+ L G P Sbjct: 1016 PDTLGAPATLPDLLARAVAAHPEAVAVVAGASRLTYRELADRTNRLSRWLIERGIGPESR 1075 Query: 1588 VALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFD 1647 VA+ + RS D VA+ AV+ GAAY+P+D P R+ F+L DA+P + R Sbjct: 1076 VAVAMTRSVDLPVALAAVVGAGAAYVPVDIEYPDERVAFLLSDARPACVLVDAAGAHRLS 1135 Query: 1648 GFDLQVVEVD------DPAVEIYPSTTL------LTPSPDDIAYMIYTSGTTGVPKGVAI 1695 V VD A+ PS + + PD AY+IYTSG+TG PKGVA+ Sbjct: 1136 SVPTAVPLVDLGTDAVRAAIAEMPSNPVSDDDRTVRLRPDAAAYVIYTSGSTGRPKGVAV 1195 Query: 1696 THGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSP 1755 H +V + + VW+ +HS FD +VWE+WGALLHG +V+V A SP Sbjct: 1196 AHRSVVTLFERTGPLFRFDASDVWTMFHSYAFDFAVWEMWGALLHGATVVVVDRDTARSP 1255 Query: 1756 DDLHALLVSEGVNVLYQTPSAV---------RMMSPEGLEGTALVVAGEACPTEVVDRWA 1806 D ALL SEGV VL QTP A R GL ++ GE + W Sbjct: 1256 RDFLALLRSEGVTVLSQTPGAFGQLVEAVTRRDAGEPGLRLRHVIFGGEVLDPGQLSGWF 1315 Query: 1807 VDR-----VMINAYGPTESTIYAA---ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRPV 1858 R ++ N YG TE+ ++ +SA + + IG+P+P A VLDE L P Sbjct: 1316 ERRGDTHPLLTNMYGITETCVHVTHCPVSAASASHAIAGAIGNPLPGMAVRVLDERLHPA 1375 Query: 1859 PPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPGARMYRTGDLVRWGDDGQLQYL 1918 PPGVVGELY+A LT RFVA PFG G RMYRTGDL W DG L++ Sbjct: 1376 PPGVVGELYVAGAQLARGYLDRPGLTAGRFVADPFG-AGTRMYRTGDLGAWRADGTLRFA 1434 Query: 1919 GRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGT----ADP 1974 GR D QV++RGYR+ELGE+++ L+ V GV AV +A D R++GY+ + DP Sbjct: 1435 GRVDAQVQVRGYRVELGEVESVLAAVPGVGSAVAVA-SDAASGVRILGYVVASDGVRVDP 1493 Query: 1975 AAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETETEKT 2034 A R LP YMVP+ V LE LP+T +GKLDR ALPAPE + + AP E++ Sbjct: 1494 GAVREAAARTLPGYMVPSVVTVLEHLPITAHGKLDRTALPAPE-DTDRVLVAPRDPVEES 1552 Query: 2035 LAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVNTALDADLSVRTLFEAPTVAKLS 2094 +A +LG+E+ A ++ + V A D+ +R +F+APTVA L+ Sbjct: 1553 VAAAVRGLLGLEQVGVDDDFFVLGGNSLVAAQLASRVGDATGVDVGIRDVFDAPTVAGLA 1612 Query: 2095 LHVE-HDAGER 2104 V DAG R Sbjct: 1613 RRVSGTDAGPR 1623 Score = 431 bits (1108), Expect = e-118 Identities = 300/790 (37%), Positives = 405/790 (51%), Gaps = 59/790 (7%) Query: 36 PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA 95 P P +P L A V PD +A+ + D S TYRELDE SNRLA L GA PGA VA Sbjct: 3633 PAAAPALLPQLLASGAVANPDGLAVTAADGSLTYRELDERSNRLARSLVRAGAGPGAVVA 3692 Query: 96 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSRLDQY 155 +PRS ++ ++ +V K+GAA+LPVDPA+P RI M++DA +T+A R L Sbjct: 3693 CALPRSAVSVQAMWAVAKSGAAFLPVDPAYPRERIENMLADADVGVGVTSAADRRHLPDT 3752 Query: 156 -------DLAVI---DMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHN 205 D A + + D DR D + DD+AY+ YTSG+TG PK VAVTH Sbjct: 3753 VRWILLDDPATVGGGESTDAVTDR---DRTAPIHVDDVAYLIYTSGSTGRPKGVAVTHRG 3809 Query: 206 VTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLH 265 +T LV +H+ P S FD +V E+ A G LVV P V L Sbjct: 3810 LTSLVDEMHSRYPISQDARCLHVCSPSFDFAVLELLQAGAVGAALVVAPPDVYGGAA-LA 3868 Query: 266 NLLITEKVSVLCQTPSAAGMLSPEGLES-TTLIVAGEACPTELVDRWAPGRVMINAYGPT 324 +LL+ ++++ +C TP+A + P + L+V G+A TELV WA GR MI+ YGP Sbjct: 3869 DLLVAQQITHMCITPAALATVEPGRFDDLAVLVVGGDAVGTELVAGWATGRTMIDGYGPA 3928 Query: 325 EATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYI 384 E+TI S PL L VLD++LRP P GV GELYV G G+A GY Sbjct: 3929 ESTIVTTFSAPLVPGADVPIGTPVRGTGVL-VLDEYLRPVPPGVPGELYVVGAGLARGYH 3987 Query: 385 GRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQ 444 RP LTA+RFVACP G G RMYRTGD+VR DG L+YLGR+D QVK+RG RIELGEI+ Sbjct: 3988 RRPGLTAARFVACPRGAAGARMYRTGDIVRRRPDGALDYLGRSDFQVKVRGLRIELGEIE 4047 Query: 445 AALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP----AQLRTALAESLPAYMVPTAV 500 A L V +V +AR GD L Y+ D +L A LP +M+P A+ Sbjct: 4048 AVLVAHPAVAHSVTVARRRGAGDSLLASYVVPATDDGIDVTELTEFAARRLPRHMLPNAI 4107 Query: 501 VVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDS 560 VVL +P+T GKLDR ALP P++ YRAP TPAE+ + V+A++ G +RVG+DD+ Sbjct: 4108 VVLGELPVTPVGKLDRDALPEPDFGRPTAPYRAPRTPAEKQVVAVFAEITGADRVGLDDN 4167 Query: 561 FFDLGGDSILSMQVVARA-RAAGIQCRPRDIFVEQTXXXXXXXXXXXXESHV---VDEGV 616 FF LGG+S+ + +VVAR RA G RD+F T + + GV Sbjct: 4168 FFGLGGNSLGATRVVARINRALGSGLDVRDLFECGTAGRLAERAAQRARAESPAGLRGGV 4227 Query: 617 GPVVATPIMRWLREVDGPTGQFNQTVITQAPAGVTEDDVVVILQALLDRHATLRLRVEDT 676 P P + W +E QF+ T + +V+ L LD A LR + D Sbjct: 4228 RP--ERPPLSWAQERMWFVDQFDPT------SAAYNVPMVLRLTGTLDTRA-LRAALTDV 4278 Query: 677 QEDTDEWSLLVPEAGAVGARECLRTVDALTDDVLVEARNR-LDPAAGAMVSA-------V 728 E + + P + ++ + D + D R++ LD G ++ A V Sbjct: 4279 VERQESLRTVFPSGPSGPSQVTVAATDVVGDLEAEPVRHQDLDARIGDLLRAGFDVANEV 4338 Query: 729 WVR--------ETSQLVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFA 780 VR + LVL++HH+ DG S L D+ +A+A G+ P G Sbjct: 4339 PVRARILRLDPDVHVLVLVLHHIVADGFSIAPLARDVAVAYAARVAGR----PPG----- 4389 Query: 781 RWSALLAEHA 790 W L ++A Sbjct: 4390 -WEPLTVQYA 4398 Score = 429 bits (1103), Expect = e-117 Identities = 255/555 (45%), Positives = 322/555 (58%), Gaps = 17/555 (3%) Query: 36 PGPTPVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA 95 P P+ +P L A R PDA+A+V R TYR+LDE +NRLA L GA P VA Sbjct: 7295 PDAPPLLLPDLLAS-AARNPDALAVVCDGRELTYRQLDEGANRLARHLIAMGAGPEGYVA 7353 Query: 96 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTADLRSR---- 151 + RS ++L++ +V +TGAA++PVDP +P RI M++D +T R R Sbjct: 7354 LGLSRSVSSVLAVWAVARTGAAFVPVDPNYPAERIARMLADCGATVGVTVRSCRERVPGS 7413 Query: 152 -----LDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVPKAVAVTHHNV 206 LD D+A A+PA +D R D AY+ YTSG+TG PK V +TH + Sbjct: 7414 FDWVVLDDPDVAEAVAAEPATPISDADRRRPLRADHPAYLIYTSGSTGTPKGVVLTHRGL 7473 Query: 207 TQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPESVGSSPDDLHN 266 L + L P + S FD SV+E AL G +VVVP + + Sbjct: 7474 ADLAAEERDRLLVTPTARTLHFASPSFDASVFETVMALSAGATMVVVPPDIYGGTE-FAE 7532 Query: 267 LLITEKVSVLCQTPSAAGMLSPEGLEST-TLIVAGEACPTELVDRWAPGRVMINAYGPTE 325 +L T V+ TP+ L P GLES TL+VAGE CP ELV RWAPGR M+NAYGPTE Sbjct: 7533 ILATGGVTHGFVTPTTLASLDPVGLESLRTLVVAGEPCPPELVRRWAPGRTMLNAYGPTE 7592 Query: 326 ATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEGVVGELYVAGHGVATGYIG 385 TI A +S P+ + VLD L P P GVVGELYVAG +A GY Sbjct: 7593 TTIMANISAPMSPHRPVTLGGPIRGVREV-VLDSRLHPVPRGVVGELYVAGSALARGYHR 7651 Query: 386 RPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQA 445 RP TA+RFVA PFG G+R+YRTGDLVRW +D LEY+GR+D QVK+RG+RIE GEI Sbjct: 7652 RPGTTAARFVADPFGAAGDRLYRTGDLVRWRTDDTLEYVGRSDFQVKVRGFRIEPGEIDT 7711 Query: 446 ALAKLDGVDQAVVIAREDRPGDKRLVGYITGT----ADPAQLRTALAESLPAYMVPTAVV 501 LA GV AV +AR G+ L Y+ T DP ++R A+A LPA+MVP+AV Sbjct: 7712 VLAAQPGVGFAVTLARRGPAGNMLLCSYVCPTVDAHVDPDEMRRAVARHLPAHMVPSAVT 7771 Query: 502 VLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADVYAQVLGVERVGVDDSF 561 VLD +PLT GKLDR ALP P + +A YR P P E + D +A VLGVER+G+DDSF Sbjct: 7772 VLDRVPLTPTGKLDRDALPPPAFLAAPAVYREPQGPVETAVVDAFADVLGVERIGMDDSF 7831 Query: 562 FDLGGDSILSMQVVA 576 FDLGG S+L+ +VA Sbjct: 7832 FDLGGTSLLATGLVA 7846 Score = 417 bits (1072), Expect = e-113 Identities = 324/1047 (30%), Positives = 476/1047 (45%), Gaps = 92/1047 (8%) Query: 1117 YAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFVEQFGEPVQVLTADPMIAWRYLDL 1176 Y V + + +TG LD LR A+ VV R +L F P QV A + DL Sbjct: 4254 YNVPMVLRLTGTLDTRALRAALTDVVERQESLRTVFPSGPSGPSQVTVAATDVVG---DL 4310 Query: 1177 RGDDLTPDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVIDGWSLP 1236 + + +++ A D+ RA ++R + H VL HHIV DG+S+ Sbjct: 4311 EAEPVR-HQDLDARIGDLLRAGFDVANEVPVRARILRLDPDVHVLVLVLHHIVADGFSIA 4369 Query: 1237 ILLQEIFAGYFGHRL-------PAAAPYRNFVNWLXXXXXXXXXXX---------WREVL 1280 L +++ Y P Y +F W W + L Sbjct: 4370 PLARDVAVAYAARVAGRPPGWEPLTVQYADFALWQRRVLGDPDDPSSMLAREEAYWLDRL 4429 Query: 1281 DGFETPTLVAPPGVPGPR-----GIESYRVSAETTRALGELARSQHTTINTVLQAAWTQL 1335 G T + G R G V + RAL ++A +T+ V+ A L Sbjct: 4430 AGAPPVTTLPLDRPRGARRSTRGGRVELSVGPDVHRALSDIAEQHDSTMFMVVHTALAVL 4489 Query: 1336 LMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRAKVSADTTVGDLLRQLQSHH 1395 L R+ RDV GT V+GR A + +VG+ +NT+ +R ++ G +L +++ Sbjct: 4490 LARIGQDRDVVIGTPVAGRGE--AELDDVVGMFVNTLALRTEIDPAAAFGAVLTRVRDVD 4547 Query: 1396 NDTLEHEHLALNDIHHVSGHEQ------LFDTLFLYESYPIDTSAFMG--VQELAVTEFN 1447 + H L L + SG E+ LF L + + G V+ + + Sbjct: 4548 VEAFAHADLPLERLVVRSGAERTTSYAPLFQVLLEFRNVEAPRLGLPGLTVESVGIEARE 4607 Query: 1448 NREYNHYPLSVM-ALPGHELGLRVE--YDTSVFDVSEIETLIDRFQRLLEAMIDDPARRL 1504 + + + G GLR E Y T +FD S L RLL A+ DP + Sbjct: 4608 AKFDLQFGIGEQHDERGAPAGLRGEIVYATDIFDESTAAGLARMLSRLLTAVAGDPGIAV 4667 Query: 1505 SSMDVVDDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGESLNYG 1564 + ++D A + PV + ++ ++F DP+A AV E + Y Sbjct: 4668 GDVGLIDAP-----------APVAVPVTAEGTLADLFGAAAAADPDAVAVVCGDERITYR 4716 Query: 1565 ELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARL 1624 +LD +N+LA L G P VA+ + R+ D + A+ +++ GAAYLP+DP P R+ Sbjct: 4717 DLDAHSNRLARWLIERGIGPESVVAVAMERTVDLVAALAGIVRAGAAYLPVDPGYPPERI 4776 Query: 1625 EFMLGDAKPVAAVTTGDLRSRFDGFDL----QVVEVD----------DPAVEIYPSTTLL 1670 F++ DA +T + L ++V +D P+ + + Sbjct: 4777 GFVVRDAGARTLLTDAGSAAGLSDVPLPEHTEIVGLDAEDVRQRIEGRPSGPVADHERVR 4836 Query: 1671 TPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVS 1730 PD AY+IYTSG+TG PKGV +TH NV +L + VW+ +HS FD + Sbjct: 4837 RLHPDSPAYVIYTSGSTGRPKGVVVTHRNVVTLLSGARDVIGFDASDVWTLFHSYAFDFA 4896 Query: 1731 VWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSAVRMM------SPEG 1784 VWE+WGAL GGR+V+V A +PDDL ALL +E V +L QTPSA + S Sbjct: 4897 VWELWGALGFGGRVVVVDRHTARAPDDLVALLAAESVTLLSQTPSAFGQLARAEADSDRP 4956 Query: 1785 LEGTALVVAGEACPTEVVDRWAVDR-----VMINAYGPTESTIY--------AAISAPLS 1831 L +V GEA + WA R +IN YG TE+ ++ A + + + Sbjct: 4957 LALRRVVFGGEALDATRLADWAARRGADRPALINMYGITETCVHVTWHPVAAAEVDSSRT 5016 Query: 1832 PGSDVVPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVAC 1891 GS IG +P VLD+ L PVP GVVGELY+A LT +RFV Sbjct: 5017 VGS---VIGVGLPGIGVRVLDDRLHPVPVGVVGELYVAGPQVARGYLHRPDLTASRFVPD 5073 Query: 1892 PFGEPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAV 1951 P P RMYR+GD VRW G L+Y+GRAD QV++RG+R+E GE++AAL+ V GV AV Sbjct: 5074 PCA-PSRRMYRSGDRVRWTRSGDLEYIGRADFQVQVRGFRVEPGEVEAALTAVPGVAAAV 5132 Query: 1952 VIAREDRPGDKRLVGYITGTADPAAARSELTN----RLPAYMVPAAVVTLETLPLTVNGK 2007 V+AR + G RL+GY+ +T+ RLP+YMVP+ V L PLT NGK Sbjct: 5133 VLARAESAGADRLLGYVVPEPGQTVTAETVTDAVGQRLPSYMVPSTVTVLGEFPLTSNGK 5192 Query: 2008 LDRRALPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRV 2067 +DR ALP P + R P T+ E+ L +FA VLG E ++++ Sbjct: 5193 IDRAALPDPRPVGGEG-RPPATDVERILTDLFADVLGAESVGVDDSFFGLGGDSIMSIQL 5251 Query: 2068 TAAVNTALDADLSVRTLFEAPTVAKLS 2094 + A ++ R +FE TVA+L+ Sbjct: 5252 VSRAKAA-GVTITPRDVFECRTVARLA 5277 Score = 407 bits (1046), Expect = e-110 Identities = 313/922 (33%), Positives = 434/922 (47%), Gaps = 83/922 (9%) Query: 30 RAVLTDPGPT---PVTIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEH 86 RA+ T P T P T+P L A V P+AVA+V+G TYREL + +NRL+ L E Sbjct: 1009 RALSTLPPDTLGAPATLPDLLARAVAAHPEAVAVVAGASRLTYRELADRTNRLSRWLIER 1068 Query: 87 GAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTTA 146 G P + VA + RS + +++ +V+ GAAY+PVD +PD R+ F++SDA+P L A Sbjct: 1069 GIGPESRVAVAMTRSVDLPVALAAVVGAGAAYVPVDIEYPDERVAFLLSDARPACVLVDA 1128 Query: 147 DLRSRLDQYDLAV------IDMADPAIDRRPSDALSGP------RPDDLAYMTYTSGTTG 194 RL AV D AI PS+ +S RPD AY+ YTSG+TG Sbjct: 1129 AGAHRLSSVPTAVPLVDLGTDAVRAAIAEMPSNPVSDDDRTVRLRPDAAAYVIYTSGSTG 1188 Query: 195 VPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVP 254 PK VAV H +V L VW+ +HS FD +VWE+WGALLHG +VVV Sbjct: 1189 RPKGVAVAHRSVVTLFERTGPLFRFDASDVWTMFHSYAFDFAVWEMWGALLHGATVVVVD 1248 Query: 255 ESVGSSPDDLHNLLITEKVSVLCQTPSAAGML---------SPEGLESTTLIVAGEACPT 305 SP D LL +E V+VL QTP A G L GL +I GE Sbjct: 1249 RDTARSPRDFLALLRSEGVTVLSQTPGAFGQLVEAVTRRDAGEPGLRLRHVIFGGEVLDP 1308 Query: 306 ELVDRWAPGR-----VMINAYGPTEATIYAA---MSEPLXXXXXXXXXXXXXXXXXLFVL 357 + W R ++ N YG TE ++ +S + VL Sbjct: 1309 GQLSGWFERRGDTHPLLTNMYGITETCVHVTHCPVSAASASHAIAGAIGNPLPGMAVRVL 1368 Query: 358 DKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGS 417 D+ L PAP GVVGELYVAG +A GY+ RP LTA RFVA PFG G RMYRTGDL W + Sbjct: 1369 DERLHPAPPGVVGELYVAGAQLARGYLDRPGLTAGRFVADPFG-AGTRMYRTGDLGAWRA 1427 Query: 418 DGQLEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGT 477 DG L + GR D QV++RGYR+ELGE+++ LA + GV AV +A D R++GY+ + Sbjct: 1428 DGTLRFAGRVDAQVQVRGYRVELGEVESVLAAVPGVGSAVAVA-SDAASGVRILGYVVAS 1486 Query: 478 ----ADPAQLRTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRA 533 DP +R A A +LP YMVP+ V VL+ +P+T +GKLDR ALPAPE A Sbjct: 1487 DGVRVDPGAVREAAARTLPGYMVPSVVTVLEHLPITAHGKLDRTALPAPE--DTDRVLVA 1544 Query: 534 PSTPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR-ARAAGIQCRPRDIFV 592 P P E+ +A +LG+E+VGVDD FF LGG+S+++ Q+ +R A G+ RD+F Sbjct: 1545 PRDPVEESVAAAVRGLLGLEQVGVDDDFFVLGGNSLVAAQLASRVGDATGVDVGIRDVFD 1604 Query: 593 EQTXXXXXXXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTV--ITQ--APA 648 T V GP P++ R P Q + + Q + Sbjct: 1605 APT--------VAGLARRVSGTDAGPRARPPLVARPRPPRIPLSPAQQRIWFVNQFDTDS 1656 Query: 649 GVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRTVDA---- 704 + + L LLDR A L + D + + P A G R+ + +D Sbjct: 1657 AAYNISLSLKLSGLLDRDA-LDEAIGDVVARHESLRTVYPLDDA-GPRQEVLPLDRTGLG 1714 Query: 705 -----LTDDVLVEARNRLDPAAGAMVSA--------VWVRETSQ-LVLMIHHLAVDGVSW 750 + D+ ++ R R + G VSA + +T L +++HH+ DG S Sbjct: 1715 IDRADVDDEADLQQRMRALMSRGFDVSAQVPLRAGLFRLGDTEHVLTVVLHHILADGFSL 1774 Query: 751 RILLEDLNIAWAQHCTG---QSIELPAGGTSFARWSALL---AEHAKTDTVRDLADAWRA 804 +L DL A+A P +A W + A+ + R L D W Sbjct: 1775 GVLARDLVTAYATRTASGVPSRTPRPVQYADYALWQSEWLGDADDPASLLARQL-DYWTT 1833 Query: 805 VTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQL---LGEVPAAFRAGVQDILLVAFG 861 + A+ + D Q ++ E QL + E+ A A V ++ A Sbjct: 1834 TLADLPAVLDLPCDRARPDVRSQQGGRVEFELPAQLHARIVELARAHDASVFMVMHAALA 1893 Query: 862 LAWTEFLNRSDTPIGVDVEGHG 883 + D +G + G G Sbjct: 1894 VLLARLGGTEDVTVGTPIAGRG 1915 Score = 73.2 bits (178), Expect = 5e-10 Identities = 116/412 (28%), Positives = 168/412 (40%), Gaps = 82/412 (19%) Query: 478 ADPAQLRTALAE-SLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPST 536 ADP + +LAE L A PT+ PL+V R PAP ++ R P Sbjct: 422 ADPQR---SLAEVHLGAAPAPTSA---SPTPLSV-----RSEQPAP------SEQREPDA 464 Query: 537 P--AEQILADVYAQVLGVER-VGVDDSFFDLGGDSILSMQVVARARAA-GIQCRPRDIFV 592 EQ++ DV+ +VL R V +DSFFDLGGDS+++ +VVAR AA G+ RD+F Sbjct: 465 DDVTEQVIVDVFTEVLHANRPVRPEDSFFDLGGDSLVATKVVARLNAALGVTLTVRDLFE 524 Query: 593 EQTXXXXXXXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTV--ITQAPAG- 649 T E+ + PV P+ R R P Q + + Q G Sbjct: 525 APTAHRLAGHVGASRETDGATD--APVPLLPLARPDRPARLPLSPAQQRMWFVNQLDTGS 582 Query: 650 -----------VTEDDVVVILQAL---LDRHATLRLRVEDTQEDTDEWSLLVPEAGAV-- 693 + DV + A+ ++RH LR E + ++VP AV Sbjct: 583 PVYNIAFAVTLTGQLDVAALRAAIGDVVERHEALRTVFPVDAEGPQQ--VIVPAESAVPD 640 Query: 694 ---------GARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHHLA 744 ARE +R V + DV R +P + + E L +++HH+A Sbjct: 641 VTPAAAERHEAREQIRRVSVVGFDV------REEPPLRVQLFRLGPEE-HVLAVVVHHIA 693 Query: 745 VDGVSWRILLEDLNIAWAQHCTG---QSIELPAGGTSFARW----------SALLAEHAK 791 DG S L D+ +A+A G + LP +A W +A H Sbjct: 694 ADGQSVSPLARDVMVAYAARRAGGPPRWTPLPVQYADYALWQRDMLGDERDGRSVAAHQL 753 Query: 792 TDTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDV--ETTRQLL 841 LAD A+ ALP +P + T T G + +LDV +T R+LL Sbjct: 754 QYWTARLADLPPAI-----ALPHDRPRSATMTTRG-ATVTLDVGADTHRRLL 799 Score = 63.9 bits (154), Expect = 3e-07 Identities = 88/360 (24%), Positives = 138/360 (38%), Gaps = 32/360 (8%) Query: 1094 PLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARFV 1153 PL+ Q+ L F A + ++ Q + I G LD RLR A + R V Sbjct: 12 PLSEAQRALWFAQQLAPDV--PLFIAQY-VDIHGPLDIDRLRAANVRAAHEFESPFLRVV 68 Query: 1154 EQFGEPVQVLTADPMIAWRYLDLRG--DDLTPDHEIEQLCAAERSAVCDLLERPTFRAAL 1211 G+P+Q + + +DLR D + H Q E + DL + + Sbjct: 69 TVDGDPMQYVDPARDTSIELVDLRAHVDPVAAAHVWMQ---REIATPVDLSVDRLVQTVI 125 Query: 1212 IRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH------RLPAAAPYRNFVN--- 1262 + + HHI +DG+ +L I Y PAA R+ + Sbjct: 126 LEVGDRHFLWYSRSHHIALDGYGAATMLYRIAHLYTAAVEGREPDPPAATDLRSLHDIDE 185 Query: 1263 -WLXXXXXXXXXXXWREVLDGFETPTLVAPPGVPGPRGIESYRVSAE-TTRALGELARSQ 1320 + W LDG TLV G P ES V++ + RA+ L RS+ Sbjct: 186 RYRASDRHDTDRAYWAHRLDGVRGVTLV---GAGAPAVAESRLVTSPLSNRAMRRLERSE 242 Query: 1321 H-----TTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIR 1375 + + AA+ L R TG RDV VS R + G+ +N VP+R Sbjct: 243 DGQGPDASAAARIIAAFACFLSRTTGSRDVVVDIPVSARTTAVLRRSG--GMTVNLVPVR 300 Query: 1376 AKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDIHHVSGHE---QLFDTLFLYESYPIDT 1432 ++ D TVG L+ ++Q L H+ + DI G + + + +F + +D+ Sbjct: 301 VEMRDDDTVGALVGRVQVELVAALRHQRCSRADIQRDLGTDLTAPIVNVMFFHPEIVMDS 360 Score = 43.9 bits (102), Expect = 0.33 Identities = 46/143 (32%), Positives = 61/143 (42%), Gaps = 16/143 (11%) Query: 1972 ADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRALPAPEYQSAQRYRAPETET 2031 ADP + +E+ L A P + PL+V R PAP S QR + T Sbjct: 422 ADPQRSLAEV--HLGAAPAPTSA---SPTPLSV-----RSEQPAP---SEQREPDADDVT 468 Query: 2032 EKTLAGIFAHVLGVERXXXXXXXXXXXXXXXX-AMRVTAAVNTALDADLSVRTLFEAPTV 2090 E+ + +F VL R A +V A +N AL L+VR LFEAPT Sbjct: 469 EQVIVDVFTEVLHANRPVRPEDSFFDLGGDSLVATKVVARLNAALGVTLTVRDLFEAPTA 528 Query: 2091 AKLSLHVEHDAGERTDRVSFAAV 2113 +L+ HV A TD + A V Sbjct: 529 HRLAGHV--GASRETDGATDAPV 549 >tr|A5WIF6|A5WIF6_MYCTF Tax_Id=336982 SubName: Full=Peptide synthetase nrp;[Mycobacterium tuberculosis] Length = 2512 Score = 1327 bits (3433), Expect = 0.0 Identities = 773/1511 (51%), Positives = 959/1511 (63%), Gaps = 65/1511 (4%) Query: 1093 LPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTVVARHPNLAARF 1152 +PL+ Q+ L F R VY + + + + G LD L AV VV RH +L F Sbjct: 1023 IPLSFAQRRLWFLDQLQRPA--PVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVF 1080 Query: 1153 VEQFGEPVQVLTADPMIAWRYLDLRGD--DLT--PDHEIEQLCAAERSAVCDLLERPTFR 1208 G P Q++ I R DL D D T P +++ DL R Sbjct: 1081 PAVDGVPRQLV-----IEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLR 1135 Query: 1209 AALIRTSGNQHRFVLTFHHIVIDGWSLPILLQEIFAGYFGH---RLPAAAP----YRNFV 1261 L R + ++H V HHI DGWS+ L ++ A Y R P AP Y ++ Sbjct: 1136 TWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYT 1195 Query: 1262 NWLXXXXXXXXXXX---------WREVLDGF----ETPTLVAPPGVPGPRGIESY-RVSA 1307 W W L G PT P V RG A Sbjct: 1196 LWQREILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPA 1255 Query: 1308 ETTRALGELARSQHTTINTVLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGL 1367 + + +AR + T V+ A + LL +++G DVA G ++GR +D A +++VG Sbjct: 1256 SVQQQVRRIARQHNATSFMVVAAGFAVLLSKLSGSPDVAVGFPIAGR-SDPA-LDNLVGF 1313 Query: 1368 LINTVPIRAKVSADTTVGDLLRQLQSHHNDTLEHEHLALNDI------HHVSGHEQLFDT 1421 +NT+ +R ++ D + +LL Q+++ E++ + + H L Sbjct: 1314 FVNTLVLRVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQV 1373 Query: 1422 LFLYESYPIDTSAFMGVQE--LAVTEFNNREYNHYPLSVMALPGHE---LGLRVEYDTSV 1476 + ++ P+ +Q + + R + L+ G E +G VEY T V Sbjct: 1374 MLAWQDNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDV 1433 Query: 1477 FDVSEIETLIDRFQRLLEAMIDDPARRLSSMDVVDDDERTQLDEWANRAVLTQPVDSPQS 1536 F+ I+ LI+R +++L A+ P R +SS+D +D ER +LDEW NRAVLT P +P S Sbjct: 1434 FEAQAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVS 1493 Query: 1537 IPEVFARQVERDPEAPAVTFEGESLNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSA 1596 IP++ A QV R PEA AV S+ Y ELDEA+N+LA+ LA GA PG+ VAL+ R A Sbjct: 1494 IPQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCA 1553 Query: 1597 DAIVAILAVLKTGAAYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEV 1656 A+VA++AVLKTGAAYLPIDP+ P R+ FMLGDA PVAAVTT LRSR G DL +++V Sbjct: 1554 PAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDV 1613 Query: 1657 DDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTLPAELPAGPG 1716 D A+ YP T P+ ++AY++YTSGTTG PKGV ITH NVT++ +LPA L A Sbjct: 1614 VD-ALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQ- 1671 Query: 1717 AVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDLHALLVSEGVNVLYQTPSA 1776 VWSQ HS FD S WEIWGALL GGRLVIVPES+A SP+D H LLV+E V+VL QTP+A Sbjct: 1672 -VWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAA 1730 Query: 1777 VRMMSPEGLEGTALVVAGEACPTEVVDRWAVDRVMINAYGPTESTIYAAISAPLSPGSDV 1836 V M+ +GLE ALVVAGEACP +VDRWA RVM+NAYGPTE+TI AAISAPL PGS + Sbjct: 1731 VAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGM 1790 Query: 1837 VPIGSPVPKGATFVLDEWLRPVPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEP 1896 PIG PV A FVLD WLRPVP GV GELY+A LT +RFVACPFG Sbjct: 1791 PPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGS 1850 Query: 1897 GARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIARE 1956 GARMYRTGDLV W DGQL++LGR D+QVKIRGYRIELGE+ AL+++ GV QAVVIARE Sbjct: 1851 GARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIARE 1910 Query: 1957 DRPGDKRLVGYIT----GTADPAAARSELTNRLPAYMVPAAVVTLETLPLTVNGKLDRRA 2012 DRPGDKRLVGY T G DPA R++L RLP Y+VPAAVV ++ LPLTVNGKLD RA Sbjct: 1911 DRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRA 1970 Query: 2013 LPAPEYQSAQRYRAPETETEKTLAGIFAHVLGVERXXXXXXXXXXXXXXXXAMRVTAAVN 2072 LPAPEY YRAP EKT+AGIFA VLG+ER AMRV AA+N Sbjct: 1971 LPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGDSLAAMRVIAAIN 2030 Query: 2073 TALDADLSVRTLFEAPTVAKLSLHVEHDAGERTDRVSFAAVHGSDVTEVHARDLTLDKFI 2132 T L+ADL VR L A + LS + DA +D +VHG + TEVHA DLTLD+FI Sbjct: 2031 TTLNADLPVRALLHASSTRGLSQLLGRDARPTSD-PRLVSVHGDNPTEVHASDLTLDRFI 2089 Query: 2133 XXXXXXXXXXXXXXXGAVQTVLLTGATGFLGRYLLLEWLRQLRRVDDKVICLVRGKSDED 2192 ++TVLLTGATGFLGRYL+LE LR+L VD ++ICLVR +SDED Sbjct: 2090 DADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRL-DVDGRLICLVRAESDED 2148 Query: 2193 ARRRLEATFDT-DPLLRKHFNELATERLQVVAGDKGQPNLGLDEQTWQRLAESVDLIVDS 2251 ARRRLE TFD+ DP L +HF ELA +RL+VVAGDK +P+LGLD+ W+RLAE+VDLIVDS Sbjct: 2149 ARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDS 2208 Query: 2252 AAFVNSVLPYSELFGPNVVGTAELIRFALTSKLKPFNFVSTSDVGRQIEPSRFTEQADIR 2311 AA VN+ PY ELFGPNV GTAELIR ALT+KLKPF +VST+DVG IEPS FTE ADIR Sbjct: 2209 AAMVNA-FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDADIR 2267 Query: 2312 LVSATRKIEVGYANGYGNSKWAGEVLLREAHDHCGLPVAVFRSGMIMVDPTYAGQLNVTD 2371 ++S TR ++ G+A GYG SKWAGEVLLREA+D C LPVAVFR GMI+ D +YAGQLN++D Sbjct: 2268 VISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMILADTSYAGQLNMSD 2327 Query: 2372 TVSRMVLSIVATGVAPGSFYQRGDNGERQRAHFDGLPVDFVAQAITKLGWQVARSVTDST 2431 V+RMVLS++ATG+AP SFY+ G RQRAHFDGLPV FVA+AI LG +VA S+ Sbjct: 2328 WVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLPVTFVAEAIAVLGARVA----GSS 2383 Query: 2432 ASGFETYHVMNPHDDGIGIDTYIDWLIEAGYPIERIEDFGEWLQRFEAALQGLSDQQRQN 2491 +GF TYHVMNPHDDGIG+D Y+DWLIEAGYPI RI+DF EWLQRFEA+L L D+QR++ Sbjct: 2384 LAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDFAEWLQRFEASLGALPDRQRRH 2443 Query: 2492 SVLQMLTLLKQQAGELQPPVPTRGSFAPADRFQAAVRDANIGVE---GEIPHVTREVIVK 2548 SVL M LL + LQP PTRG AP DRF+AAVR A +G + +IPHV+ I+ Sbjct: 2444 SVLPM--LLASNSQRLQPLKPTRGCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIIN 2501 Query: 2549 YVTDLQLLGLL 2559 YVT+LQLLGLL Sbjct: 2502 YVTNLQLLGLL 2512 Score = 691 bits (1782), Expect = 0.0 Identities = 359/573 (62%), Positives = 421/573 (73%), Gaps = 8/573 (1%) Query: 8 RTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPALFAEQVVRAPDAVALVSGDRSW 67 RT+ S D LD E +++ WGNRAVLT P PTPV+IP + A QV R P+A A+ GD S Sbjct: 1459 RTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASM 1518 Query: 68 TYRELDEASNRLAHVLAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPD 127 TYRELDEASNRLAH LA GA PG VA L R A++++++VLKTGAAYLP+DPA+P Sbjct: 1519 TYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDPANPP 1578 Query: 128 ARIGFMMSDAKPVAALTTADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMT 187 R+ FM+ DA PVAA+TTA LRSRL +DL +ID+ D A+ P P +LAY+ Sbjct: 1579 PRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVD-ALAAYPGTPPPMPAAVNLAYIL 1637 Query: 188 YTSGTTGVPKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHG 247 YTSGTTG PK V +TH NVT+L ++L A L + QVWSQ HS FD S WEIWGALL G Sbjct: 1638 YTSGTTGEPKGVGITHRNVTRLFASLPARLSAA--QVWSQCHSYGFDASAWEIWGALLGG 1695 Query: 248 GRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTTLIVAGEACPTEL 307 GRLV+VPESV +SP+D H LL+ E VSVL QTP+A ML +GLES L+VAGEACP L Sbjct: 1696 GRLVIVPESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQGLESVALVVAGEACPAAL 1755 Query: 308 VDRWAPGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKWLRPAPEG 367 VDRWAPGRVM+NAYGPTE TI AA+S PL LFVLD WLRP P G Sbjct: 1756 VDRWAPGRVMLNAYGPTETTICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAG 1815 Query: 368 VVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQLEYLGRA 427 V GELY+AG GV GY R LTASRFVACPFG +G RMYRTGDLV W +DGQLE+LGR Sbjct: 1816 VAGELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGRT 1875 Query: 428 DEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYIT----GTADPAQL 483 D+QVKIRGYRIELGE+ ALA+L GV QAVVIAREDRPGDKRLVGY T G DPA L Sbjct: 1876 DDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGL 1935 Query: 484 RTALAESLPAYMVPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILA 543 R LA+ LP Y+VP AVVV+D +PLTVNGKLD RALPAPEY N YRAP+ P E+ +A Sbjct: 1936 RAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAPEY-GDTNGYRAPAGPVEKTVA 1994 Query: 544 DVYAQVLGVERVGVDDSFFDLGGDSILSMQVVA 576 ++A+VLG+ERVGVDDSFF+LGGDS+ +M+V+A Sbjct: 1995 GIFARVLGLERVGVDDSFFELGGDSLAAMRVIA 2027 Score = 123 bits (308), Expect = 4e-25 Identities = 209/905 (23%), Positives = 339/905 (37%), Gaps = 151/905 (16%) Query: 83 LAEHGAKPGATVAFLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAA 142 L + GA PG + F + + I +++ G Y D A + +++ Sbjct: 475 LVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGIL 534 Query: 143 LTTADLRSRLDQYDLAVID------MADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGVP 196 +T D+ + LAV+ + D + + DAL + AY+ TSGTTG P Sbjct: 535 VTVVDVAAT----QLAVVGHDELRKVVDERVTQVTHDALLATKT---AYIMPTSGTTGQP 587 Query: 197 KAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALLHGGRLVVVPES 256 K V ++H ++ A+ G Q L D+SV EI+G G RLV S Sbjct: 588 KLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RS 644 Query: 257 VGSSPDDLHNLL--ITEKVSVLCQTPSAAGML---SPEGLES------TTLIVAGEACPT 305 DL L+ + + + + P+A L + +++ +++ GEA Sbjct: 645 AAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRC 704 Query: 306 ELVDRW-----APGRVMINAYGPTEATIYAAMSEPLXXXXXXXXXXXXXXXXXLFVLDKW 360 VD+W + G ++++YGPTEAT+ A P+ + + Sbjct: 705 SAVDKWLESAASQGISLLSSYGPTEATVVATFL-PIVCDQTTMDGALLRLGRPILPNTVF 763 Query: 361 LRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFVACPFGETGERMYRTGDLVRWGSDGQ 420 L GE+ + G VA GY+G D V G + R + TGD V ++G Sbjct: 764 L------AFGEVVIVGDLVADGYLG-IDGDGFGTVTAADG-SRRRAFATGDRVTVDAEGF 815 Query: 421 LEYLGRADEQVKIRGYRIELGEIQAALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADP 480 + GR D VKI G R+++ E+ +A+ V V G V + + Sbjct: 816 PVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLG----VWFKSQRTRE 871 Query: 481 AQLRTALAESLPAYMVPTA-----VVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPS 535 + A A + +V VV + IP NGK+D LP SAA A + Sbjct: 872 GEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAET 931 Query: 536 TPAEQILADVYAQVLGVERVGVDDSFFDLGGDSILSMQVVARARA-AGIQCRPRDIFVEQ 594 L+ ++++ LG +G D S G S+ ++++ R G + D+ Sbjct: 932 GQRAAGLSQIWSRQLG-RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDL---- 986 Query: 595 TXXXXXXXXXXXXESHVVDEGVGPVVATPIMRWLREVDGPTGQ--FNQTVITQAPAGVTE 652 +G A + + D PTG+ F V Q PA + Sbjct: 987 ---------------------IGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPL 1025 Query: 653 D---------DVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGAVGARECLRT-- 701 D + + + LRLR DT+ V A VG E LRT Sbjct: 1026 SFAQRRLWFLDQLQRPAPVYNMAVALRLR---GYLDTEALGAAV--ADVVGRHESLRTVF 1080 Query: 702 --VDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQ------------------------ 735 VD + +++EAR R D + + W + Q Sbjct: 1081 PAVDGVPRQLVIEAR-RADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLF 1139 Query: 736 --------LVLMIHHLAVDGVSWRILLEDLNIAWAQHCTGQSIE---LPAGGTSFARWS- 783 LV + HH+A DG S L DL+ A+A C G++ + LP + W Sbjct: 1140 RIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQR 1199 Query: 784 ALLAEHAKTDT--VRDLADAWRAVTSVPQ--ALPPVQPDTDTYVTAGQLSASLDVE---T 836 +L + +D+ LA A+ +P+ LP +P A Q ASL V+ + Sbjct: 1200 EILGDLDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPP---VADQRGASLVVDWPAS 1256 Query: 837 TRQLLGEVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDVDLSR 896 +Q + + A ++ F + ++ D +G + G SD L Sbjct: 1257 VQQQVRRIARQHNATSFMVVAAGFAVLLSKLSGSPDVAVGFPIAGR-------SDPALDN 1309 Query: 897 TVGWF 901 VG+F Sbjct: 1310 LVGFF 1314 Score = 88.2 bits (217), Expect = 2e-14 Identities = 118/490 (24%), Positives = 190/490 (38%), Gaps = 47/490 (9%) Query: 1581 GAAPGKSVALMVPRSADAIVAILAVLKTGAAYLPIDPSVPAARLEFML---GDAKPVAAV 1637 GAAPG + + I ++A G Y D + + + GD V V Sbjct: 479 GAAPGDVLVFTDDDTDKTIDLLIACHLAGCGYSVCDTADEISVRTNAITEHGDGILVTVV 538 Query: 1638 TTGDLRSRFDGFDLQVVEVDDPAVEIYPSTTLLTPSPDDIAYMIYTSGTTGVPKGVAITH 1697 + G D VD+ ++ L T + AY++ TSGTTG PK V I+H Sbjct: 539 DVAATQLAVVGHDELRKVVDERVTQVTHDALLATKT----AYIMPTSGTTGQPKLVRISH 594 Query: 1698 GNVTQVLDTLPAELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDD 1757 G++ D + G Q L D+SV EI+G G RLV S A D Sbjct: 595 GSLAVFCDAISRAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLV---RSAAMKTGD 651 Query: 1758 LHAL---LVSEGVNVLYQTPSAVRMMSPEGLEGTA--------LVVAGEACPTEVVDRWA 1806 L AL LV+ ++ + +++ +G A +V+ GEA VD+W Sbjct: 652 LAALVDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCSAVDKWL 711 Query: 1807 VDRV-----MINAYGPTESTIYAA----ISAPLSPGSDVVPIGSPVPKGATFVLDEWLRP 1857 ++++YGPTE+T+ A + + ++ +G P+ F+ Sbjct: 712 ESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGALLRLGRPILPNTVFL------- 764 Query: 1858 VPPGVVGELYLAXXXXXXXXXXXXXLTGTRFVACPFGEPG-ARMYRTGDLVRWGDDGQLQ 1916 GE+ + + G F + R + TGD V +G Sbjct: 765 ----AFGEVVIV---GDLVADGYLGIDGDGFGTVTAADGSRRRAFATGDRVTVDAEGFPV 817 Query: 1917 YLGRADEQVKIRGYRIELGEIQAALSDVDGVDQAVVIAREDRPGDKRLVGYITGTADPAA 1976 + GR D VKI G R+++ E+ +++ V V G AA Sbjct: 818 FSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELHSGSLGVWFKSQRTREGEQDAA 877 Query: 1977 ARSELTNRLPAYMVPA-AVVTLETLPLTVNGKLDRRALP-APEYQSAQRYRAPETETEKT 2034 A + + L + V + VV + +P NGK+D LP P++ +A A + Sbjct: 878 AATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAG 937 Query: 2035 LAGIFAHVLG 2044 L+ I++ LG Sbjct: 938 LSQIWSRQLG 947 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.319 0.135 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 21,090,873,469 Number of extensions: 917180879 Number of successful extensions: 2599711 Number of sequences better than 10.0: 28431 Number of HSP's gapped: 2420388 Number of HSP's successfully gapped: 77504 Length of query: 2559 Length of database: 4,236,830,644 Length adjustment: 156 Effective length of query: 2403 Effective length of database: 2,285,603,860 Effective search space: 5492306075580 Effective search space used: 5492306075580 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 90 (39.3 bits)