BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_0408 (3652 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|Q3L885|Q3L885_MYCS2 Tax_Id=246196 (pks)SubName: Full=Polyketi... 6800 0.0 tr|A1T1R8|A1T1R8_MYCVP Tax_Id=350058 SubName: Full=Beta-ketoacyl... 5544 0.0 tr|Q1BFG9|Q1BFG9_MYCSS Tax_Id=164756 SubName: Full=Beta-ketoacyl... 5537 0.0 tr|A3PT20|A3PT20_MYCSJ Tax_Id=164757 SubName: Full=Beta-ketoacyl... 5537 0.0 tr|A1U9G3|A1U9G3_MYCSK Tax_Id=189918 SubName: Full=Beta-ketoacyl... 5537 0.0 tr|A5A9S2|A5A9S2_MYCCH Tax_Id=1774 (pks)SubName: Full=Pks protei... 5495 0.0 tr|B1MJ75|B1MJ75_MYCA9 Tax_Id=561007 SubName: Full=Probable poly... 5479 0.0 tr|A4T3X4|A4T3X4_MYCGI Tax_Id=350054 SubName: Full=Beta-ketoacyl... 5479 0.0 tr|A5A9V0|A5A9V0_MYCAB Tax_Id=36809 (pks)SubName: Full=Pks prote... 5479 0.0 tr|A0QDK0|A0QDK0_MYCA1 Tax_Id=243243 SubName: Full=Tylactone syn... 5248 0.0 tr|Q73XS9|Q73XS9_MYCPA Tax_Id=1770 SubName: Full=Putative unchar... 5241 0.0 tr|A1T3U1|A1T3U1_MYCVP Tax_Id=350058 SubName: Full=Beta-ketoacyl... 4578 0.0 tr|D5PHA5|D5PHA5_9MYCO Tax_Id=525368 SubName: Full=Putative unch... 3458 0.0 tr|D1SGL1|D1SGL1_9ACTO Tax_Id=644283 SubName: Full=KR domain pro... 1950 0.0 tr|Q53840|Q53840_SORCE Tax_Id=56 (sorB)SubName: Full=Soraphen po... 1908 0.0 tr|B1W4J4|B1W4J4_STRGG Tax_Id=455632 (pks2-4)SubName: Full=Putat... 1889 0.0 tr|A4F5C6|A4F5C6_SORCE Tax_Id=56 (spiG)SubName: Full=Polyketide ... 1885 0.0 tr|Q6W5P9|Q6W5P9_9ACTO Tax_Id=206662 (fscB)SubName: Full=FscB;[S... 1858 0.0 tr|A0ACH1|A0ACH1_STRAM Tax_Id=278992 SubName: Full=Putative poly... 1835 0.0 tr|A4D934|A4D934_9NOSO Tax_Id=76335 (crpB)SubName: Full=CrpB;[No... 1768 0.0 tr|Q9KIV3|Q9KIV3_STRAT Tax_Id=1890 (oleAII)SubName: Full=8,8a-de... 1759 0.0 tr|Q52V53|Q52V53_9ACTO Tax_Id=255848 SubName: Full=Polyketide sy... 1651 0.0 tr|Q3S864|Q3S864_9ACTO Tax_Id=42238 SubName: Full=Nodular polyke... 1645 0.0 tr|D1SGG4|D1SGG4_9ACTO Tax_Id=644283 SubName: Full=Short-chain d... 1645 0.0 tr|Q52V44|Q52V44_9ACTO Tax_Id=255848 SubName: Full=Polyketide sy... 1640 0.0 tr|D3C7A9|D3C7A9_9ACTO Tax_Id=648999 SubName: Full=Mycocerosate ... 1639 0.0 tr|Q52V46|Q52V46_9ACTO Tax_Id=255848 SubName: Full=Polyketide sy... 1639 0.0 tr|Q8GBX6|Q8GBX6_SORCE Tax_Id=56 (spiH)SubName: Full=Polyketide ... 1636 0.0 tr|A4F5C7|A4F5C7_SORCE Tax_Id=56 (spiH)SubName: Full=Polyketide ... 1636 0.0 tr|C9YYI1|C9YYI1_STRSW Tax_Id=680198 SubName: Full=Putative type... 1628 0.0 tr|B4VBW0|B4VBW0_9ACTO Tax_Id=465541 SubName: Full=Polyketide sy... 1627 0.0 tr|B6ZIR4|B6ZIR4_STRPT Tax_Id=58346 (pldAIII)SubName: Full=Polyk... 1607 0.0 tr|Q82QT4|Q82QT4_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular... 1604 0.0 tr|Q93H87|Q93H87_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular... 1604 0.0 tr|Q9X993|Q9X993_9ACTO Tax_Id=68242 (pimS1)SubName: Full=PimS1 p... 1588 0.0 tr|Q3S869|Q3S869_9ACTO Tax_Id=42238 SubName: Full=Modular polyke... 1587 0.0 tr|B6ZIR3|B6ZIR3_STRPT Tax_Id=58346 (pldAII)SubName: Full=Polyke... 1583 0.0 tr|C9YYI3|C9YYI3_STRSW Tax_Id=680198 SubName: Full=Putative type... 1576 0.0 tr|Q8GBX5|Q8GBX5_SORCE Tax_Id=56 (spiI)SubName: Full=Polyketide ... 1569 0.0 tr|Q93H84|Q93H84_STRAW Tax_Id=33903 (pteA4)SubName: Full=Modular... 1565 0.0 tr|B6ZIR2|B6ZIR2_STRPT Tax_Id=58346 (pldAI)SubName: Full=Polyket... 1565 0.0 tr|D3Y1I4|D3Y1I4_9ACTO Tax_Id=529089 SubName: Full=TamAII;[Strep... 1554 0.0 tr|D5PHA4|D5PHA4_9MYCO Tax_Id=525368 SubName: Full=Putative unch... 1553 0.0 tr|Q68BG4|Q68BG4_STRHA Tax_Id=1944 (hlsB)SubName: Full=Type I po... 1551 0.0 tr|D0LQW0|D0LQW0_HALO1 Tax_Id=502025 SubName: Full=Acyl transfer... 1550 0.0 >tr|Q3L885|Q3L885_MYCS2 Tax_Id=246196 (pks)SubName: Full=Polyketide synthase; SubName: Full=Type I modular polyketide synthase;[Mycobacterium smegmatis] Length = 3652 Score = 6800 bits (17643), Expect = 0.0 Identities = 3456/3652 (94%), Positives = 3456/3652 (94%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD Sbjct: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS Sbjct: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV Sbjct: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA Sbjct: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA Sbjct: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL Sbjct: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG Sbjct: 361 EAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL 480 VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL Sbjct: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL 480 Query: 481 RAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEA 540 RAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEA Sbjct: 481 RAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEA 540 Query: 541 PKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD 600 PKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD Sbjct: 541 PKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD 600 Query: 601 TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGAR 660 TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGAR Sbjct: 601 TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGAR 660 Query: 661 LIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESA 720 LIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESA Sbjct: 661 LIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESA 720 Query: 721 VATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS 780 VATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS Sbjct: 721 VATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS 780 Query: 781 TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVL 840 TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVL Sbjct: 781 TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVL 840 Query: 841 ASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI 900 ASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI Sbjct: 841 ASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI 900 Query: 901 DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRS 960 DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRS Sbjct: 901 DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRS 960 Query: 961 THVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVALPG 1020 THVDPDARYEIRWD DWILVGDDTAAVLEFADALTAGGHRHQIVALPG Sbjct: 961 THVDPDARYEIRWDAIASAAASTGAAADWILVGDDTAAVLEFADALTAGGHRHQIVALPG 1020 Query: 1021 SDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAE 1080 SDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAE Sbjct: 1021 SDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAE 1080 Query: 1081 LRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI 1140 LRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI Sbjct: 1081 LRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI 1140 Query: 1141 ARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG 1200 ARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG Sbjct: 1141 ARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG 1200 Query: 1201 YLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAE 1260 YLASHGAGHVVLTSRREP EQYACDVRVITADVADAHDVARLMTTVAAE Sbjct: 1201 YLASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHDVARLMTTVAAE 1260 Query: 1261 LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS 1320 LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS Sbjct: 1261 LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS 1320 Query: 1321 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGV 1380 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGV Sbjct: 1321 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGV 1380 Query: 1381 RTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXX 1440 RTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESEL Sbjct: 1381 RTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAA 1440 Query: 1441 XXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSL 1500 LVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSL Sbjct: 1441 APATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSL 1500 Query: 1501 MAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDD 1560 MAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDD Sbjct: 1501 MAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDD 1560 Query: 1561 PIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRXX 1620 PIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTR Sbjct: 1561 PIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRFG 1620 Query: 1621 XXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGV 1680 PEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGV Sbjct: 1621 GFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGV 1680 Query: 1681 AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQ 1740 AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQ Sbjct: 1681 AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQ 1740 Query: 1741 ACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGV 1800 ACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGV Sbjct: 1741 ACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGV 1800 Query: 1801 LVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADV 1860 LVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADV Sbjct: 1801 LVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADV 1860 Query: 1861 DYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVV 1920 DYLEAHGTGTPLGDPIEVQ PLLMGSVKTNIGHTESASGAAGLIKVV Sbjct: 1861 DYLEAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESASGAAGLIKVV 1920 Query: 1921 LSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHV 1980 LSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHV Sbjct: 1921 LSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHV 1980 Query: 1981 LVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPG 2040 LVEEAPPQLH GTDDSPQVLALSARSPEALVELARRYDDWLSATPG Sbjct: 1981 LVEEAPPQLHTADAAPVEPAATAEAGTDDSPQVLALSARSPEALVELARRYDDWLSATPG 2040 Query: 2041 LDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAW 2100 LDIADVCHTAGVGRSHFEYRAALVVDSV TPAGVVRGEHVHRPTTAW Sbjct: 2041 LDIADVCHTAGVGRSHFEYRAALVVDSVERAREGLAALAEGRTPAGVVRGEHVHRPTTAW 2100 Query: 2101 LFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHT 2160 LFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHT Sbjct: 2101 LFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHT 2160 Query: 2161 SFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRM 2220 SFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRM Sbjct: 2161 SFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRM 2220 Query: 2221 FGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFEDEG 2280 FGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFEDEG Sbjct: 2221 FGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFEDEG 2280 Query: 2281 IRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYW 2340 IRCTWLATSHAFHSELLDPVLD PTLPLVCNRTGAVLTGQTPLDAQYW Sbjct: 2281 IRCTWLATSHAFHSELLDPVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYW 2340 Query: 2341 RRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVA 2400 RRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVA Sbjct: 2341 RRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVA 2400 Query: 2401 DRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAAS 2460 DRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAAS Sbjct: 2401 DRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAAS 2460 Query: 2461 GILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARLKD 2520 GILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARLKD Sbjct: 2461 GILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARLKD 2520 Query: 2521 VFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD 2580 VFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD Sbjct: 2521 VFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD 2580 Query: 2581 PDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI 2640 PDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI Sbjct: 2581 PDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI 2640 Query: 2641 LVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMP 2700 LVGAELAEQLGSEPMHPVLMDLCTGV EQGVNDLFLPLRYGQVTLAEKMP Sbjct: 2641 LVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEKMP 2700 Query: 2701 RRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRL 2760 RRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRL Sbjct: 2701 RRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRL 2760 Query: 2761 LYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARG 2820 LYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARG Sbjct: 2761 LYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARG 2820 Query: 2821 AGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHG 2880 AGFSGVVWRCATPGRK ITNLLSAVHAAQGPSVKLPGGLWIVTEHG Sbjct: 2821 AGFSGVVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQGPSVKLPGGLWIVTEHG 2880 Query: 2881 VACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPE 2940 VACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVD PGIQEPE Sbjct: 2881 VACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPE 2940 Query: 2941 IAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQV 3000 IAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQV Sbjct: 2941 IAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQV 3000 Query: 3001 RVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFAS 3060 RVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFAS Sbjct: 3001 RVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFAS 3060 Query: 3061 RFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAI 3120 RFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAI Sbjct: 3061 RFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAI 3120 Query: 3121 QMAQQSGAEVFATASTFKRSTLRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTS 3180 QMAQQSGAEVFATASTFKRSTLRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTS Sbjct: 3121 QMAQQSGAEVFATASTFKRSTLRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTS 3180 Query: 3181 AGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLL 3240 AGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLL Sbjct: 3181 AGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLL 3240 Query: 3241 TEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLIT 3300 TEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKI DRSYLIT Sbjct: 3241 TEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQPQQDRSYLIT 3300 Query: 3301 GGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEA 3360 GGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEA Sbjct: 3301 GGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEA 3360 Query: 3361 QVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXX 3420 QVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASH Sbjct: 3361 QVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDD 3420 Query: 3421 XXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASS 3480 PGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASS Sbjct: 3421 DLDFFIVSSSVSSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASS 3480 Query: 3481 EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLV 3540 EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLV Sbjct: 3481 EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLV 3540 Query: 3541 LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTD 3600 LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTD Sbjct: 3541 LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTD 3600 Query: 3601 SLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA 3652 SLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA Sbjct: 3601 SLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA 3652 >tr|A1T1R8|A1T1R8_MYCVP Tax_Id=350058 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium vanbaalenii] Length = 3676 Score = 5544 bits (14381), Expect = 0.0 Identities = 2828/3679 (76%), Positives = 3081/3679 (83%), Gaps = 60/3679 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M SAEHP P P FAI+GYAARFPGA A+ +W +LR+GR+AISDVP+DRWD EEFFDP+ Sbjct: 1 MGSAEHPNGPAPRFAIVGYAARFPGAPDADAFWDVLREGRDAISDVPRDRWDAEEFFDPE 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFVDDVTGFDAPFFGMS REVR+MDPQHR+L+ETAWRAVEHSG APT+ Sbjct: 61 PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQHRLLLETAWRAVEHSGTAPTA 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LA SNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV Sbjct: 121 LAGSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQALRL ECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA Sbjct: 181 DTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGV+V+KRLEDAVRDGDRIRAVIRGS+INQDGASGGLTVPNGVAQQRVIA Sbjct: 241 AADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIA 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DALKR+ L P DVGYLEAHGTGTSLGDPIEAQAAG VLGAGR P PLLIGSAKTNIGHL Sbjct: 301 DALKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPSRPLLIGSAKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LE+ TLPKHLNFE PSPHIPW+RL +EVV+ET+PW+R+G PRIAG Sbjct: 361 EAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLAVEVVKETIPWERDGGPRIAG 420 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDP-RRYSVLPLSARTPEALVRLAGEYRDW 479 VSSFGFAGTNAHVILEEAP A PV+ P RR+S+LPLSARTP AL +LAG+YRDW Sbjct: 421 VSSFGFAGTNAHVILEEAPE--QAAAPGPVQQPDRRFSLLPLSARTPAALTQLAGQYRDW 478 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 AHP+A LADV TAG RAHLE RAALVVNS ESA+ELLGALADDRPAPGLVRGESH+ Sbjct: 479 WTAHPEATLADVCFTAGAGRAHLEHRAALVVNSAESAVELLGALADDRPAPGLVRGESHD 538 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 PKTAWLFTGQGSQYPGMAREL+DTEPVFAET+ +CAEAVAD+LEKPLLDVIFDA+ Sbjct: 539 TPKTAWLFTGQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAEA--D 596 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 D E L++T YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQYSAACVAGVF + DGA Sbjct: 597 DAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVFSLTDGA 656 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLES 719 RL+AERGRLFGSLP GGRM AVFT ERAE +TDE+PSLSVAAYNG NTVLSGPA DLE Sbjct: 657 RLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEFPSLSVAAYNGTNTVLSGPAGDLEK 716 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 AVATL ADGVRCDWLDTSHAFHSALLDPILDDFES+A + ++ PQRILIDNRTG+ALGR Sbjct: 717 AVATLSADGVRCDWLDTSHAFHSALLDPILDDFESYANQFDFAAPQRILIDNRTGTALGR 776 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 S +LDG YWRRHARQPVEFAKSVRTLA+MNC++L+EIGPRPVLTA AL AWPDPAT P+V Sbjct: 777 SVQLDGTYWRRHARQPVEFAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAPRV 836 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 +ASLR T ADHRQITEAVA AY GHLP+F AFR ARKLDLPTYPFEHRQ+WF DN Sbjct: 837 IASLRRTAADHRQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFRDN-- 894 Query: 900 IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQR 959 +D + A T+AVRLLEDG+IEELA L+DG D+QTL VL++LAA+HNQQR Sbjct: 895 --QDPDGSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTLDVLSRLAAQHNQQR 952 Query: 960 STHVDPDARYEIRWD--XXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVA 1017 S+ + RYEIRW+ WILVGDDT A D L+A G R++I Sbjct: 953 SSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVGDDTEATRPLVDVLSARGQRYRIFG 1012 Query: 1018 LPGSDADEAQLVDTLRAASAGE--LYVVHIAAGD-----GAAAPMRDLLRVQHRTLGGLR 1070 LP SDADE QL + LR A+A + L +VH+ D G A MR LLR+QHR LGG R Sbjct: 1013 LPVSDADEEQLGEALRLAAAEDSTLRIVHVGGLDSDPDPGTAPSMRSLLRMQHRILGGTR 1072 Query: 1071 RLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLS 1130 RLFRAA AELR+PIW+VTR Q VT TDTV P+QSCLWGFGRAAALELP +WGGLADL+ Sbjct: 1073 RLFRAAAAAELRTPIWVVTRRAQHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLA 1132 Query: 1131 -GADTEWPRLIARITSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYL 1186 G EW RL+ RIT+P EDQIALR AVY PRLVRR G P+ PL +R+D TYL Sbjct: 1133 DGTADEWSRLLNRITAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDDATYL 1192 Query: 1187 VTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVAD 1246 VTGGLG+IGLE+AGYLA+HGA H+VLTSRR P Q++C +RV+ ADVAD Sbjct: 1193 VTGGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRIDALGAQHSCQIRVVAADVAD 1252 Query: 1247 AHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALT 1306 AHDVARL+ VAAELPPLAGIVHAAGEIGTTPL L+D+EVDRVFAGKVWGAWHLSEA Sbjct: 1253 AHDVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSLEDSEVDRVFAGKVWGAWHLSEAAA 1312 Query: 1307 DLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGM 1366 DL+ LDFF+ TSSIASVWGG+GQTAYGAANAFLDGLAWRLRE+G++ VS+NFGPW+AGM Sbjct: 1313 DLQ--LDFFLGTSSIASVWGGYGQTAYGAANAFLDGLAWRLREQGISGVSINFGPWSAGM 1370 Query: 1367 ADAESRARLEQRGVRTLSPAEALAGMADVVA-----GPVQGVVAKIDWSRFLPLYQQAGR 1421 ADAESRARL+QRGVRTLSPA+ALAG+ADVV GP QG+VA+IDW RFLPLYQQAGR Sbjct: 1371 ADAESRARLDQRGVRTLSPADALAGLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGR 1430 Query: 1422 RAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRV 1481 RAFL+ELE E+ LVE+LT APVQQRK L+T+YLR AVAE+TRV Sbjct: 1431 RAFLAELEREV----PDTAPAATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAEITRV 1486 Query: 1482 DADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLG 1541 DA EIR++AGFFDLGMDSLMAVELRRRIEQGVG++IP TL MDHPRLSD ADYLL EVLG Sbjct: 1487 DATEIREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPRLSDVADYLLGEVLG 1546 Query: 1542 LGEQTNVR----QASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPED 1597 L EQ + AS RTD+PIA+VAVSCRFPGAPDPE+FWE+LAGGVDAIREVPED Sbjct: 1547 LAEQAPAKAGSQPASAAANRTDEPIAIVAVSCRFPGAPDPEAFWEVLAGGVDAIREVPED 1606 Query: 1598 RWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWE 1657 R+DIDEFYDPDPD GKTYTR PEFFGISPREAVWIEPQQRLMLETVWE Sbjct: 1607 RFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWE 1666 Query: 1658 GLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFA 1717 GLERAG AP+DLRGSRTG+F GVAANEYAHLLS+ESI+KIEPHFITGNALNAISGRVAFA Sbjct: 1667 GLERAGLAPADLRGSRTGIFVGVAANEYAHLLSSESIEKIEPHFITGNALNAISGRVAFA 1726 Query: 1718 LGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLS 1777 LG EGPAVAVDTACSSALVAVHQACQAL SGDCDLALAGGVNVLLSPVT VAASRARMLS Sbjct: 1727 LGLEGPAVAVDTACSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTSVAASRARMLS 1786 Query: 1778 PVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVP 1837 PVGRCKTFDASADGYVRSEGCG+LVLKRL DAVRDGDRVCAVIP+S+VNQDGASSGLTVP Sbjct: 1787 PVGRCKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRVCAVIPSSAVNQDGASSGLTVP 1846 Query: 1838 NGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLM 1897 NGGAQQRLI LARAGLSG DVDYLEAHGTGTPLGDPIEVQ PLLM Sbjct: 1847 NGGAQQRLIGMALARAGLSGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGASRDADRPLLM 1906 Query: 1898 GSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPW 1957 GSVKTNIGH ESASGAAGLIKVVLSLQH +LPQSLHFENPSPHIPWD+LPVRV+D+ +PW Sbjct: 1907 GSVKTNIGHLESASGAAGLIKVVLSLQHNLLPQSLHFENPSPHIPWDSLPVRVVDKAIPW 1966 Query: 1958 QTNGRVRRAGVSSFGFTGTNAHVLVEEAP-PQLHXXXXXXXXXXXXXXXGTDDSPQVLAL 2016 Q +GR RRAGVSSFGFTGTNAHVL+EEAP PQ VLAL Sbjct: 1967 QADGRPRRAGVSSFGFTGTNAHVLIEEAPLPQAADPVEEPDTRALPVG--------VLAL 2018 Query: 2017 SARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXX 2076 SARSPEAL LA+RY+ WLSA P D+ADVC TAG GRSHFE+RAALVVDSV Sbjct: 2019 SARSPEALTALAQRYEAWLSAHPDADLADVCRTAGTGRSHFEHRAALVVDSVAAAREGLA 2078 Query: 2077 XXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVAD 2136 GVVRGEH H PTTAWLFTGQGSQ+PGMARELF+T+PVFA V +CA+AV D Sbjct: 2079 ELAQNRLRPGVVRGEHTHHPTTAWLFTGQGSQFPGMARELFETEPVFADAVTRCADAVKD 2138 Query: 2137 MLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQY 2196 +LPRPLL+VLFA DRE+ + L+HTSFAQPA+FAVEMGLARLWQSW IEPDVVLGHSVGQY Sbjct: 2139 ILPRPLLEVLFAADRESGEALRHTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQY 2198 Query: 2197 AAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYN 2256 AAACVAGVFSL+DGARLMAERGRMFGSLPEGGRMVAVF DA+ VE++AG+FPRVSVGAYN Sbjct: 2199 AAACVAGVFSLEDGARLMAERGRMFGSLPEGGRMVAVFTDAKLVEEIAGDFPRVSVGAYN 2258 Query: 2257 GPNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXP 2316 GPNTVLSGPGEDLE+IV+RF D+G+RCTWL TSHAFHSELLDPVLD P Sbjct: 2259 GPNTVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLDEFESYAAQFQFATP 2318 Query: 2317 TLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG 2376 TLPLVCNRTG VLT QTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG Sbjct: 2319 TLPLVCNRTGTVLTAQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG 2378 Query: 2377 AAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPT 2436 +AVQVWPEH+AAPRA+ SLRKGV+DRRQI +ALA+AYVGGHRPDF A++R+P R V LPT Sbjct: 2379 SAVQVWPEHLAAPRAIVSLRKGVSDRRQITEALAAAYVGGHRPDFGALYRRPGRAVALPT 2438 Query: 2437 YPFQRRRFWPKASSIAVDGGTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGT 2496 YPFQRRRFWPK S I D G A SGILGS KDLASGDT+YTSR SV+SQPWLADHVIYGT Sbjct: 2439 YPFQRRRFWPKTSGITTD-GPAVSGILGSAKDLASGDTVYTSRWSVRSQPWLADHVIYGT 2497 Query: 2497 VVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHS 2556 VVVPGATYAAMALAAVGTPAR+KDVFFYEPIILPEKASREVQLTLHP++ G FQ+HS Sbjct: 2498 VVVPGATYAAMALAAVGTPARVKDVFFYEPIILPEKASREVQLTLHPSEDGG-QKFQVHS 2556 Query: 2557 RPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLEL 2616 R YGERG +WSLNAEGTV +G D + A E S PVDE IERL RMRPQDLFETFAD+EL Sbjct: 2557 REYGERGTEWSLNAEGTV-ASGVDENPQA-EPSGPVDEAIERLNRMRPQDLFETFADMEL 2614 Query: 2617 AWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXX 2676 AWGPTWSGSLKSLWLG+GEA+GDILVG ELAEQLG+EPMHPVLMDLCTGV Sbjct: 2615 AWGPTWSGSLKSLWLGEGEAIGDILVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLA 2674 Query: 2677 XEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGI 2736 EQGV+DLFLPLRYGQVTL +KMPRRFYCRA WH S LDSETQVF+L+F+D GR LGGI Sbjct: 2675 AEQGVSDLFLPLRYGQVTLRDKMPRRFYCRATWHTSELDSETQVFDLDFLDRDGRHLGGI 2734 Query: 2737 REFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAV-GTWLIAGFDELAAKVP 2795 REFTVKRAPREALLRGLGGDATRLLYTLGWHEVP P S D A+ G WLIAGFDELAA VP Sbjct: 2735 REFTVKRAPREALLRGLGGDATRLLYTLGWHEVPAPASGDAALNGNWLIAGFDELAAGVP 2794 Query: 2796 GCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNL 2855 GC+P DR+TD + LG++L+QAH RG GFSGVVWR A P I +L Sbjct: 2795 GCIPFDRSTDPEPLGQLLAQAHERGIGFSGVVWRAAAP--SADESSTAMAARIETEIADL 2852 Query: 2856 LSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLV 2915 LSAVH Q +VKLPGGLWIVTE VA ESGEPVDPVQAALWGFGRTTINEEPAL CRLV Sbjct: 2853 LSAVHTVQNGAVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRCRLV 2912 Query: 2916 DCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPT 2975 D DGS EAV P + EPE+AVRQGKLLASRLLPWARSGHLT+PR D+VLAPT Sbjct: 2913 DVDGSPEAVLALAGLLAAP-VDEPELAVRQGKLLASRLLPWARSGHLTVPRSADYVLAPT 2971 Query: 2976 ERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVT 3035 ERGAIDNLRLTETDV P EGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVT Sbjct: 2972 ERGAIDNLRLTETDVAPPAEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVT 3031 Query: 3036 QLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF 3095 QLG+GV+GLE+GQRVYG MQGAFASRFNVPAQ LAPIPDGIGAV+AATIPAAALT RLAF Sbjct: 3032 QLGSGVTGLEVGQRVYGFMQGAFASRFNVPAQLLAPIPDGIGAVDAATIPAAALTARLAF 3091 Query: 3096 DWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGVKYVYDSRT 3155 DWAQLKPGD+VLIHAASGGVGLAAIQMAQQ GA VFATAST+KR+TLR+LGV +VYDSRT Sbjct: 3092 DWAQLKPGDRVLIHAASGGVGLAAIQMAQQHGAVVFATASTYKRATLRKLGVDHVYDSRT 3151 Query: 3156 TDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEAR 3215 T+FADQILADT+G GVDVVLNSLT+ GF+EAT++ATAQ GRFAEIAKRDIW+ EQMA AR Sbjct: 3152 TEFADQILADTDGEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIAKRDIWTPEQMAAAR 3211 Query: 3216 PDIAYEIVALDTVMFTEPDRIRDLLTEVSDGM------ARGEWTPLPAEIYPITEARSAF 3269 PDIAYEIVALDTV EP+RIR LL EVSDG+ +R EW PLPAEIYP+TEAR+AF Sbjct: 3212 PDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGKADGSSRAEWVPLPAEIYPLTEARAAF 3271 Query: 3270 RRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRD 3329 RRMQQARH+GKI DRSYLITGGLGAIGLHTAAYLAQLGAGD+VLTSRR Sbjct: 3272 RRMQQARHVGKIVLQMPKPLQPRADRSYLITGGLGAIGLHTAAYLAQLGAGDLVLTSRRA 3331 Query: 3330 PDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDA 3389 PD A+RAI+EITER+KCR+HT+ ADVGDE+QVA+LLARIRAELPPLAG+AHLAGVLDDA Sbjct: 3332 PDADARRAIEEITERYKCRVHTFCADVGDESQVAELLARIRAELPPLAGVAHLAGVLDDA 3391 Query: 3390 LLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAM 3449 LLS Q+ ERFRTTLAPKA+GA H PGQANYATANA+ Sbjct: 3392 LLSQQSLERFRTTLAPKAFGACHLDRLTAGDDLDFFIMSSSVSSLFGSPGQANYATANAL 3451 Query: 3450 LDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALAEVIA 3509 LDGL A RRA+GL ATG+NFGPW QGGMASSEAATANI AQGL+PL+PSAAL ALAEV+A Sbjct: 3452 LDGLTAHRRARGLPATGVNFGPWAQGGMASSEAATANIGAQGLVPLEPSAALGALAEVLA 3511 Query: 3510 NGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGF 3569 NG+GQA VLKANWQRAAKVLGS+RPPILDLVLP GE GDSELL+QL EIP+ QRAGF Sbjct: 3512 NGTGQAAVLKANWQRAAKVLGSSRPPILDLVLPRPEGEVAGDSELLRQLQEIPVAQRAGF 3571 Query: 3570 VTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDY 3629 VTEFLQREVQNFLRLA PPAA+SRFLDLGTDSLMAIELRNRLHSQFGG FTINATAVFDY Sbjct: 3572 VTEFLQREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDY 3631 Query: 3630 PTIGGLAEYLVGQLPDAEA 3648 PTIGGLAEYLVGQLPD++A Sbjct: 3632 PTIGGLAEYLVGQLPDSDA 3650 >tr|Q1BFG9|Q1BFG9_MYCSS Tax_Id=164756 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium sp.] Length = 3693 Score = 5537 bits (14363), Expect = 0.0 Identities = 2833/3693 (76%), Positives = 3087/3693 (83%), Gaps = 68/3693 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M SA +P P FAI+GYAARFPGA A+E+W LLRDGREAIS+VP+DRW+++EFFDP+ Sbjct: 19 MESAAYPHVPANRFAIVGYAARFPGAQDADEFWDLLRDGREAISEVPQDRWNVDEFFDPE 78 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFVDDVTGFDAPFFGMS REVRLMDPQHR+L+ETAWRAVEHSG APT Sbjct: 79 PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGTAPTD 138 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LANSNTGVFVGLATHDYLGMASDEL+YPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV Sbjct: 139 LANSNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 198 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQAL+L ECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA Sbjct: 199 DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 258 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGV+V+KRLEDA+RDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI Sbjct: 259 AADGYVRGEGCGVIVIKRLEDALRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIT 318 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DALKRAG+R DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGR P PLLIGSAKTNIGHL Sbjct: 319 DALKRAGVRAGDVGYLEAHGTGTSLGDPIEAQAAGEVLGAGREPSRPLLIGSAKTNIGHL 378 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LE+ETLPKHLNF TPSPHIPW+RL ++VV E+ PW+RNG+PRIAG Sbjct: 379 EAAAGIAGVIKVILSLEHETLPKHLNFTTPSPHIPWDRLAVKVVTESTPWERNGRPRIAG 438 Query: 421 VSSFGFAGTNAHVILEEAP-AVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDW 479 VSSFGFAGTNAHVILEEAP + TPA T E R+S+LPLSARTP ALVR+A YR W Sbjct: 439 VSSFGFAGTNAHVILEEAPESTVTPAATP--EPGERFSLLPLSARTPAALVRIADRYRSW 496 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 + HP+A LADV TA TARAHLEQRAALVV+SRESA+ELLGALADDRPAPGLVRGESH+ Sbjct: 497 MTTHPEATLADVCFTASTARAHLEQRAALVVDSRESAVELLGALADDRPAPGLVRGESHD 556 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 PKTAWLFTGQGSQYPGMARELFDTEPVFAET+++CA AVAD+LEKPLLDVIFDA Sbjct: 557 TPKTAWLFTGQGSQYPGMARELFDTEPVFAETMKQCAAAVADVLEKPLLDVIFDAH--GP 614 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 + LR T+YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQY+AACVAGV +EDGA Sbjct: 615 EAAETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLGLEDGA 674 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLES 719 RL+AERGRLFGSLPAGGRM AVFTA ER E +TDEYP LSVAAYNGANTVLSGPA DLE Sbjct: 675 RLMAERGRLFGSLPAGGRMVAVFTAAERVENITDEYPRLSVAAYNGANTVLSGPAGDLEK 734 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 AVATL ADG+RCDWLDTSHAFHSALLDPILD+FES+AQ++EY PQR+LIDNRTG+ALG Sbjct: 735 AVATLAADGIRCDWLDTSHAFHSALLDPILDEFESYAQQIEYAAPQRVLIDNRTGAALGW 794 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 S +LDG YWRRHARQPVEFAKSVRTLA++NC+VLLEIGPRPVLTA AL+AWPDPAT P+ Sbjct: 795 SAKLDGTYWRRHARQPVEFAKSVRTLAELNCKVLLEIGPRPVLTAAALSAWPDPATAPRA 854 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 +ASLR TADHRQITEA+A AY GH PDF A ++PDA KLDLPTYPFEHRQ+ F DN+A Sbjct: 855 IASLRRNTADHRQITEALADAYVLGHRPDFAAIQRPDAHKLDLPTYPFEHRQYSFRDNQA 914 Query: 900 IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQR 959 +R Q A RT+AV LLEDG+IEELAAL+ D QT VL+KLAA+HNQQR Sbjct: 915 -ERPEQ-AGPPIHQAARTEAVGLLEDGRIEELAALLGDTDGDRQTFDVLSKLAAQHNQQR 972 Query: 960 STHVDPDARYEIRWDXXXXXXXXXXXXXD-WILVGDDTAAVLEFADALTAGGHRHQIVAL 1018 ++ D RYEIRW+ WI+VGDDT A DA+TA G RH++V Sbjct: 973 TSQSITDDRYEIRWEELTTASPAATGEPSTWIIVGDDTDAARPLIDAVTARGDRHRLVGS 1032 Query: 1019 PGSDADEAQLVDTLRA------ASAGELYVVHIAAGDGAAAP-MRDLLRVQHRTLGGLRR 1071 P SDADEA L D LRA A G + ++HIAA D AP MR LL +QHR LG RR Sbjct: 1033 PVSDADEASLADALRASVDDASAPGGAVRILHIAALDATTAPSMRTLLSMQHRILGRTRR 1092 Query: 1072 LFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADL-- 1129 LF A LR+PIWL+TR QRVT TDTV P+QS LWGFGRAA+LELPH+WGGLADL Sbjct: 1093 LFHAVTTTGLRTPIWLITRGAQRVTATDTVAPDQSALWGFGRAASLELPHLWGGLADLPT 1152 Query: 1130 --SGADTEWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT 1184 ++ EW RL+ RI +PR EDQ+ALR AV+ PRLVRRTG+PS PL +R D T Sbjct: 1153 GPGASEDEWSRLLDRIAAPRHSDVTEDQVALRDGAVHVPRLVRRTGQPSGAPLRLRSDAT 1212 Query: 1185 YLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADV 1244 YLVTGGLGAIGLE+AGYLA+HGAG++VLTSRR P +++ C +RV TADV Sbjct: 1213 YLVTGGLGAIGLEIAGYLAAHGAGNIVLTSRRAPGDAAQQRIDALRDKFGCAIRVATADV 1272 Query: 1245 ADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDD----AEVDRVFAGKVWGAWH 1300 ADAHDVARL+ V AELPPLAGIVHAAGEIGTT LS +DD AEVDRVFAGKVWGAWH Sbjct: 1273 ADAHDVARLLAGVQAELPPLAGIVHAAGEIGTTALSAMDDESQQAEVDRVFAGKVWGAWH 1332 Query: 1301 LSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFG 1360 LSEA DL+ LDFF+STSSIASVWGGFGQTAYGAANAFLDGLAWRLRE+G+ A SVNFG Sbjct: 1333 LSEAAVDLQ--LDFFISTSSIASVWGGFGQTAYGAANAFLDGLAWRLREQGIAATSVNFG 1390 Query: 1361 PWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGP-VQGVVAKIDWSRFLPLYQQA 1419 PW+AGMADAESRARLEQRGVRTL PA+ALAG+ADVVAGP QGV+A+IDW+RFLPLYQQA Sbjct: 1391 PWSAGMADAESRARLEQRGVRTLDPADALAGLADVVAGPATQGVIARIDWARFLPLYQQA 1450 Query: 1420 GRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT 1479 GRRAFL+ELE E LVE+L+ APVQQRK L+T+YLR+AVAEVT Sbjct: 1451 GRRAFLTELEREAPVASTDAAPAVTASGKTPLVERLSGAPVQQRKKLLTDYLRDAVAEVT 1510 Query: 1480 RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEV 1539 RVD+ EIR++AGFFDLGMDSLMAVELRRR+EQGVGK+IPVTLVMDHPRLSDAADYLL EV Sbjct: 1511 RVDSAEIREDAGFFDLGMDSLMAVELRRRLEQGVGKEIPVTLVMDHPRLSDAADYLLGEV 1570 Query: 1540 LGLGEQTNVRQ----ASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVP 1595 LGL EQ AS + RTDDPIA+VAVSCRFPGAPDPE+FW+LL+GGVDAIREVP Sbjct: 1571 LGLAEQAPAESRPALASLASERTDDPIAIVAVSCRFPGAPDPEAFWDLLSGGVDAIREVP 1630 Query: 1596 EDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETV 1655 EDR+DIDEFYDPDPD GKTYTR PEFFGISPREAVWIEPQQRLMLETV Sbjct: 1631 EDRFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETV 1690 Query: 1656 WEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVA 1715 WEG+ERAG +P+DLRGSRTGVF GVAANEYAHLLS+ESI+KIEPHFITGNALNAISGRVA Sbjct: 1691 WEGIERAGLSPADLRGSRTGVFVGVAANEYAHLLSSESIEKIEPHFITGNALNAISGRVA 1750 Query: 1716 FALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARM 1775 FALG EGPAVAVDTACSSALVAVHQA QAL SGDCDLA+AGGVNVLLSPVTVVAASRARM Sbjct: 1751 FALGLEGPAVAVDTACSSALVAVHQAVQALHSGDCDLAVAGGVNVLLSPVTVVAASRARM 1810 Query: 1776 LSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLT 1835 LSPVGRCKTFDASADGYVRSEGCG+LVLKRLSDAVRDGDRVCAVIP ++VNQDGASSGLT Sbjct: 1811 LSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIPGTAVNQDGASSGLT 1870 Query: 1836 VPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPL 1895 VPNGGAQQRLI+ L RAGL+G DVDYLEAHGTGTPLGDPIEVQ PL Sbjct: 1871 VPNGGAQQRLIKTALTRAGLTGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGASRDADRPL 1930 Query: 1896 LMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPV 1955 LMGSVK+NIGH ESASGAAGLIKVVLSLQHGVLPQSLHF+NPSPHIPWD+LPVRV+DE V Sbjct: 1931 LMGSVKSNIGHLESASGAAGLIKVVLSLQHGVLPQSLHFDNPSPHIPWDSLPVRVVDEAV 1990 Query: 1956 PWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSP-QVL 2014 PWQ NGR RRAGVSSFGFTGTNAHVLVEEAP TDD P VL Sbjct: 1991 PWQPNGRPRRAGVSSFGFTGTNAHVLVEEAP---------QAPVSEDQESDTDDQPVHVL 2041 Query: 2015 ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXX 2074 LSARSPEALV LARRYD WL A P D+A VC TAG GRSHFE+RAA+VVDSV Sbjct: 2042 PLSARSPEALVALARRYDSWLGAHPDADLAGVCFTAGTGRSHFEHRAAMVVDSVASARQG 2101 Query: 2075 XXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAV 2134 T GVVRGEH +RPTTAWLFTGQGSQYP MARELFD +PVFA+TV +CA+AV Sbjct: 2102 LADLADNRTRPGVVRGEHTNRPTTAWLFTGQGSQYPRMARELFDAEPVFAETVTRCADAV 2161 Query: 2135 ADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVG 2194 MLP PLL+VLFA DRETA+ L+HTS+AQPALFAVEMGLARLWQSW + PDVVLGHSVG Sbjct: 2162 DGMLPLPLLEVLFAADRETAERLRHTSYAQPALFAVEMGLARLWQSWGVTPDVVLGHSVG 2221 Query: 2195 QYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGA 2254 QYAAACVAGVFSL+DGARLMAERGRMFGSLPEGGRMVA+FADA+ VEQ+AGEF RVSVGA Sbjct: 2222 QYAAACVAGVFSLEDGARLMAERGRMFGSLPEGGRMVAIFADAKQVEQIAGEFARVSVGA 2281 Query: 2255 YNGPNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXX 2314 YNGPNTVLSGPGEDLE+IV RF DEGIRCTWL TSHAFHSELLDPVLD Sbjct: 2282 YNGPNTVLSGPGEDLEQIVARFADEGIRCTWLETSHAFHSELLDPVLDEFESYAAQFEFA 2341 Query: 2315 XPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVL 2374 PT+P+VCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVA LGCSVLMEIGPQPVL Sbjct: 2342 APTMPVVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVATLGCSVLMEIGPQPVL 2401 Query: 2375 TGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVEL 2434 TGAAVQ+WPEH+AAPRA+ASLRKGV DRRQIADALA+AYVGG RPDFAA+ QP +EL Sbjct: 2402 TGAAVQIWPEHLAAPRAIASLRKGVGDRRQIADALAAAYVGGLRPDFAALQGQPHHRLEL 2461 Query: 2435 PTYPFQRRRFWPKASSIAVDGGTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIY 2494 PTYPFQRRRFWPK SSI VD G A SGILGS KDLASGDT+YTSRLSVKSQPWL+DHVIY Sbjct: 2462 PTYPFQRRRFWPKTSSITVD-GPATSGILGSAKDLASGDTVYTSRLSVKSQPWLSDHVIY 2520 Query: 2495 GTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQI 2554 GTVVVPGATYAAMALAAVGTPAR+KDVFFYEPIILPEK+SREVQLTLH G FQ+ Sbjct: 2521 GTVVVPGATYAAMALAAVGTPARVKDVFFYEPIILPEKSSREVQLTLHILGDGE-QKFQV 2579 Query: 2555 HSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADL 2614 HSR YG R A+WSLNAEGTV D A Q DPVDE IER RMRPQ+LFETFAD+ Sbjct: 2580 HSRSYGVRDAEWSLNAEGTVVRGVDD---APVSQDDPVDEAIERCNRMRPQELFETFADM 2636 Query: 2615 ELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXX 2674 ELAWGPTWSGSLKSLWLGDGEA+GD+LVGAELAEQLGSEP+HPVLMDLCTGV Sbjct: 2637 ELAWGPTWSGSLKSLWLGDGEAIGDVLVGAELAEQLGSEPIHPVLMDLCTGVAFPAFPAL 2696 Query: 2675 XXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALG 2734 EQGV+DLFLPLRYGQVT+ EKMPRRFYCRA+WH S LDSETQVF+L+F+ GR LG Sbjct: 2697 LAAEQGVSDLFLPLRYGQVTVQEKMPRRFYCRAKWHHSELDSETQVFDLDFISRDGRPLG 2756 Query: 2735 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPP---PSADDAVGTWLIAGFDELA 2791 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVP P P+A + G WLIAGFDELA Sbjct: 2757 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPLPAVDPAAPN--GNWLIAGFDELA 2814 Query: 2792 AKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXX 2851 A VPGC+P DR TD + LG++L+QAH RG FSGVVWR A P K Sbjct: 2815 ASVPGCIPFDRTTDPEPLGQLLTQAHERGMAFSGVVWRAAAP--KPDESSADVAARIETE 2872 Query: 2852 ITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALH 2911 I NLLSAVHA Q VKLPGGLWIVTE VACESGEPVDPVQAALWGFGRTTINEEPAL Sbjct: 2873 IANLLSAVHAVQRGEVKLPGGLWIVTERAVACESGEPVDPVQAALWGFGRTTINEEPALR 2932 Query: 2912 CRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFV 2971 C+LVDCDGS EAV+ P + EPE+A+RQGKLLASRLL WARSGHLT+PR D+V Sbjct: 2933 CKLVDCDGSPEAVEALSALLTTP-VDEPELALRQGKLLASRLLHWARSGHLTVPRSTDYV 2991 Query: 2972 LAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFA 3031 LAPTERGAIDNLRLTET+VP P EGYVQV VEAAGLNFRDVLNVLGLYPGDPGPIGGDFA Sbjct: 2992 LAPTERGAIDNLRLTETEVPPPAEGYVQVEVEAAGLNFRDVLNVLGLYPGDPGPIGGDFA 3051 Query: 3032 GTVTQLGAGVSG----------LEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEA 3081 G VTQLG GV LE+GQRVYG MQGAF+SRFNVPAQ LAPIPDG+GAVEA Sbjct: 3052 GVVTQLGDGVGSGRAERRDGIKLEVGQRVYGFMQGAFSSRFNVPAQLLAPIPDGVGAVEA 3111 Query: 3082 ATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRST 3141 ATIPAAALT RLAFDWAQL+PGD+VLIHAASGGVGLAAIQ+AQQ GA VFATAST+KR+T Sbjct: 3112 ATIPAAALTARLAFDWAQLEPGDRVLIHAASGGVGLAAIQLAQQHGAVVFATASTYKRAT 3171 Query: 3142 LRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIA 3201 LR++GV+YVYDSR+TDFADQILADT+GAGVDVVLNSLT+ GFVEAT++ATAQ GRFAEIA Sbjct: 3172 LRKMGVEYVYDSRSTDFADQILADTDGAGVDVVLNSLTNEGFVEATVRATAQNGRFAEIA 3231 Query: 3202 KRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYP 3261 KRDIW+HEQMA ARPDI+YEIVALDTV EP+RIR LL EVSDG+ +GEW PLPAEIYP Sbjct: 3232 KRDIWTHEQMAAARPDISYEIVALDTVTIQEPERIRGLLGEVSDGLGKGEWAPLPAEIYP 3291 Query: 3262 ITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGD 3321 +TEAR+AFRRMQQARHIGKI DRSYLITGGLGAIGLHTA+YLAQLGAGD Sbjct: 3292 LTEARAAFRRMQQARHIGKIVVQMPSPLQPRPDRSYLITGGLGAIGLHTASYLAQLGAGD 3351 Query: 3322 IVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAH 3381 IVLTSRR+PD Q+ IDEIT+RH+CRIHT+AADVGDE+QV +LL RIRAELPPLAG+AH Sbjct: 3352 IVLTSRREPDADTQQVIDEITDRHRCRIHTFAADVGDESQVEELLERIRAELPPLAGVAH 3411 Query: 3382 LAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQA 3441 LAGVLDDALLS Q+ ERFRTTLAPKA+GA H PGQA Sbjct: 3412 LAGVLDDALLSQQSVERFRTTLAPKAFGAYHLDHLTRDDDLDFFIVSSSVSSLFGSPGQA 3471 Query: 3442 NYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAAL 3501 NYATANA+LDGLVA+RRA GL ATG+NFGPW QGGMASSEAATANI+AQGL+PL+PSAAL Sbjct: 3472 NYATANALLDGLVARRRAHGLPATGVNFGPWAQGGMASSEAATANISAQGLVPLEPSAAL 3531 Query: 3502 HALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEI 3561 ALAEV+ANG+ QATV+KANWQRAAKVLG++RPP+LDLVLPSAAGE TGDSELL+QL EI Sbjct: 3532 SALAEVVANGTAQATVIKANWQRAAKVLGASRPPLLDLVLPSAAGEVTGDSELLRQLQEI 3591 Query: 3562 PIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTI 3621 P+ QRAGFVTEFLQREVQNFLRLA PPAASSRFLDLGTDSLMAIELRNRLHSQFGG FTI Sbjct: 3592 PVAQRAGFVTEFLQREVQNFLRLAQPPAASSRFLDLGTDSLMAIELRNRLHSQFGGAFTI 3651 Query: 3622 NATAVFDYPTIGGLAEYLVGQLPDAEAP--ETA 3652 NATAVFDYPTIGGLAEYLVGQLPDAE+P ETA Sbjct: 3652 NATAVFDYPTIGGLAEYLVGQLPDAESPAAETA 3684 Score = 1031 bits (2665), Expect = 0.0 Identities = 523/903 (57%), Positives = 630/903 (69%), Gaps = 11/903 (1%) Query: 1544 EQTNVRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDE 1603 E TN +++ + A+V + RFPGA D + FW+LL G +AI EVP+DRW++DE Sbjct: 14 EDTNGMESAAYPHVPANRFAIVGYAARFPGAQDADEFWDLLRDGREAISEVPQDRWNVDE 73 Query: 1604 FYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAG 1663 F+DP+P PGK TR FFG+S RE ++PQ RL+LET W +E +G Sbjct: 74 FFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSG 133 Query: 1664 YAPSDLRGSRTGVFTGVAANEYAHLLSAE-SIDKIEPHFITGNALNAISGRVAFALGFEG 1722 AP+DL S TGVF G+A ++Y + S E S +IE + G + A +GR+++ LG +G Sbjct: 134 TAPTDLANSNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQG 193 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PAVAVDTACSS+LVA+HQACQALQ G+CDLALAGG NVLL+P T++ S A ML+P GRC Sbjct: 194 PAVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRC 253 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 KTFDA+ADGYVR EGCGV+V+KRL DA+RDGDR+ AVI S++NQDGAS GLTVPNG AQ Sbjct: 254 KTFDAAADGYVRGEGCGVIVIKRLEDALRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQ 313 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QR+I L RAG+ DV YLEAHGTGT LGDPIE Q PLL+GS KT Sbjct: 314 QRVITDALKRAGVRAGDVGYLEAHGTGTSLGDPIEAQAAGEVLGAGREPSRPLLIGSAKT 373 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGH E+A+G AG+IKV+LSL+H LP+ L+F PSPHIPWD L V+V+ E PW+ NGR Sbjct: 374 NIGHLEAAAGIAGVIKVILSLEHETLPKHLNFTTPSPHIPWDRLAVKVVTESTPWERNGR 433 Query: 1963 VRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPE 2022 R AGVSSFGF GTNAHV++EEAP + +L LSAR+P Sbjct: 434 PRIAGVSSFGFAGTNAHVILEEAPES---------TVTPAATPEPGERFSLLPLSARTPA 484 Query: 2023 ALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXX 2082 ALV +A RY W++ P +ADVC TA R+H E RAALVVDS Sbjct: 485 ALVRIADRYRSWMTTHPEATLADVCFTASTARAHLEQRAALVVDSRESAVELLGALADDR 544 Query: 2083 TPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPL 2142 G+VRGE P TAWLFTGQGSQYPGMARELFDT+PVFA+T++QCA AVAD+L +PL Sbjct: 545 PAPGLVRGESHDTPKTAWLFTGQGSQYPGMARELFDTEPVFAETMKQCAAAVADVLEKPL 604 Query: 2143 LDVLF-ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACV 2201 LDV+F A E A+ L+ TS+AQPALFAVEMGLARLWQSW EPDVVLGHSVGQYAAACV Sbjct: 605 LDVIFDAHGPEAAETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACV 664 Query: 2202 AGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTV 2261 AGV L+DGARLMAERGR+FGSLP GGRMVAVF AE VE + E+PR+SV AYNG NTV Sbjct: 665 AGVLGLEDGARLMAERGRLFGSLPAGGRMVAVFTAAERVENITDEYPRLSVAAYNGANTV 724 Query: 2262 LSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLV 2321 LSGP DLE+ V +GIRC WL TSHAFHS LLDP+LD P L+ Sbjct: 725 LSGPAGDLEKAVATLAADGIRCDWLDTSHAFHSALLDPILDEFESYAQQIEYAAPQRVLI 784 Query: 2322 CNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQV 2381 NRTGA L LD YWRRH+RQPV+FA+SVRT+A L C VL+EIGP+PVLT AA+ Sbjct: 785 DNRTGAALGWSAKLDGTYWRRHARQPVEFAKSVRTLAELNCKVLLEIGPRPVLTAAALSA 844 Query: 2382 WPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQR 2441 WP+ APRA+ASLR+ AD RQI +ALA AYV GHRPDFAA+ R ++LPTYPF+ Sbjct: 845 WPDPATAPRAIASLRRNTADHRQITEALADAYVLGHRPDFAAIQRPDAHKLDLPTYPFEH 904 Query: 2442 RRF 2444 R++ Sbjct: 905 RQY 907 >tr|A3PT20|A3PT20_MYCSJ Tax_Id=164757 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium sp.] Length = 3702 Score = 5537 bits (14363), Expect = 0.0 Identities = 2832/3691 (76%), Positives = 3086/3691 (83%), Gaps = 66/3691 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M SA +P P FAI+GYAARFPGA A+E+W LLRDGREAIS+VP+DRW+++EFFDP+ Sbjct: 19 MESAAYPHVPANRFAIVGYAARFPGAQDADEFWDLLRDGREAISEVPQDRWNVDEFFDPE 78 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFVDDVTGFDAPFFGMS REVRLMDPQHR+L+ETAWRAVEHSG APT Sbjct: 79 PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGTAPTD 138 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LANSNTGVFVGLATHDYLGMASDEL+YPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV Sbjct: 139 LANSNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 198 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQAL+L ECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA Sbjct: 199 DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 258 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGV+V+KRLEDA+RDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI Sbjct: 259 AADGYVRGEGCGVIVIKRLEDALRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIT 318 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DALKRAG+R DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGR P PLLIGSAKTNIGHL Sbjct: 319 DALKRAGVRAGDVGYLEAHGTGTSLGDPIEAQAAGEVLGAGREPSRPLLIGSAKTNIGHL 378 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LE+ETLPKHLNF TPSPHIPW+RL ++VV E+ PW+RNG+PRIAG Sbjct: 379 EAAAGIAGVIKVILSLEHETLPKHLNFTTPSPHIPWDRLAVKVVTESTPWERNGRPRIAG 438 Query: 421 VSSFGFAGTNAHVILEEAP-AVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDW 479 VSSFGFAGTNAHVILEEAP + TPA T E R+S+LPLSARTP ALVR+A YR W Sbjct: 439 VSSFGFAGTNAHVILEEAPESTVTPAATP--EPGERFSLLPLSARTPSALVRIADRYRSW 496 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 + HP+A LADV TA TARAHLEQRAALVV+SRESA+ELLGALA+DRPAPGLVRGESH+ Sbjct: 497 MTTHPEATLADVCFTASTARAHLEQRAALVVDSRESAVELLGALAEDRPAPGLVRGESHD 556 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 PKTAWLFTGQGSQYPGMARELFDTEPVFAET+++CA AVAD+LEKPLLDVIFDA Sbjct: 557 TPKTAWLFTGQGSQYPGMARELFDTEPVFAETMKQCAAAVADVLEKPLLDVIFDAH--GP 614 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 + LR T+YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQY+AACVAGV +EDGA Sbjct: 615 EAAETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLGLEDGA 674 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLES 719 RL+AERGRLFGSLPAGGRM AVFTA ER E +TDEYP LSVAAYNGANTVLSGPA DLE Sbjct: 675 RLMAERGRLFGSLPAGGRMVAVFTAAERVENITDEYPRLSVAAYNGANTVLSGPAGDLEK 734 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 AVATL ADGVRCDWLDTSHAFHSALLDPILD+FES+AQ++EY PQR+LIDNRTG+ALG Sbjct: 735 AVATLAADGVRCDWLDTSHAFHSALLDPILDEFESYAQQIEYAAPQRVLIDNRTGAALGW 794 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 S +LDG YWRRHARQPVEFAKSVRTLA++NC+VLLEIGPRPVLTA AL+AWPDPAT P+ Sbjct: 795 SAKLDGTYWRRHARQPVEFAKSVRTLAELNCKVLLEIGPRPVLTAAALSAWPDPATAPRA 854 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 +ASLR TADHRQITEA+A AY GH PDF A ++PDA KLDLPTYPFEHRQ+ F DN+A Sbjct: 855 IASLRRNTADHRQITEALADAYVLGHRPDFAAIQRPDAHKLDLPTYPFEHRQYSFRDNQA 914 Query: 900 IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQR 959 +R Q A RT+AV LLEDG+IEELAAL+ D QT VL+KLAA+HNQQR Sbjct: 915 -ERPEQ-AGPPIHQAARTEAVGLLEDGRIEELAALLGDTDGDRQTFDVLSKLAAQHNQQR 972 Query: 960 STHVDPDARYEIRWDXXXXXXXXXXXXXD-WILVGDDTAAVLEFADALTAGGHRHQIVAL 1018 ++ D RYEIRW+ WI+VGDDT A DA+TA G RH++V Sbjct: 973 TSQSITDDRYEIRWEELTTASPAATGEPSTWIIVGDDTDAARPLIDAVTARGDRHRLVGS 1032 Query: 1019 PGSDADEAQLVDTLRA------ASAGELYVVHIAAGDGAAAP-MRDLLRVQHRTLGGLRR 1071 P SDADEA L D LRA A G + ++HIAA D AP MR LLR+QHR L RR Sbjct: 1033 PVSDADEASLADALRASVDDASAPGGAVRILHIAALDATTAPSMRTLLRMQHRILNRTRR 1092 Query: 1072 LFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADL-- 1129 LF A LR+PIWL+TR QRVT TDTV P+QS LWGFGRAA+LELPH+WGGLADL Sbjct: 1093 LFHAVTTTGLRTPIWLITRGAQRVTATDTVAPDQSALWGFGRAASLELPHLWGGLADLPT 1152 Query: 1130 --SGADTEWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT 1184 ++ EW RL+ RI +PR EDQ+ALR AV+ PRLVRRTG+PS PL +R D T Sbjct: 1153 GPGASEDEWSRLLDRIGAPRQSDVTEDQVALRDGAVHVPRLVRRTGQPSGAPLRLRSDAT 1212 Query: 1185 YLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADV 1244 YLVTGGLGAIGLE+AGYLA+HGAG+VVLTSRR P +++ C +RV TADV Sbjct: 1213 YLVTGGLGAIGLEIAGYLAAHGAGNVVLTSRRAPGDAAQQRIDALRDKFGCAIRVATADV 1272 Query: 1245 ADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDD----AEVDRVFAGKVWGAWH 1300 ADAHDVARL+ V AELPPLAGIVHAAGEIGTT LS +DD AEVDRVFAGKVWGAWH Sbjct: 1273 ADAHDVARLLAGVQAELPPLAGIVHAAGEIGTTALSAMDDESQQAEVDRVFAGKVWGAWH 1332 Query: 1301 LSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFG 1360 LSEA DL+ LDFF+STSSIASVWGGFGQTAYGAANAFLDGLAWRLRE+G+ A SVNFG Sbjct: 1333 LSEAAVDLQ--LDFFISTSSIASVWGGFGQTAYGAANAFLDGLAWRLREQGIAATSVNFG 1390 Query: 1361 PWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGP-VQGVVAKIDWSRFLPLYQQA 1419 PW+AGMADAESRARLEQRGVRTL PA+ALAG+ADVVAGP QGV+A+IDW+RFLPLYQQA Sbjct: 1391 PWSAGMADAESRARLEQRGVRTLDPADALAGLADVVAGPATQGVIARIDWARFLPLYQQA 1450 Query: 1420 GRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT 1479 GRRAFL+ELE E+ LVE+L+ APVQQRK L+T+YLR+AVAEVT Sbjct: 1451 GRRAFLTELEREVPVASTDAAPAVTASGKTPLVERLSGAPVQQRKKLLTDYLRDAVAEVT 1510 Query: 1480 RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEV 1539 RVD+ EIR++AGFFDLGMDSLMAVELRRR+EQGVGK+IPVTLVMDHPRLSDAADYLL EV Sbjct: 1511 RVDSAEIREDAGFFDLGMDSLMAVELRRRLEQGVGKEIPVTLVMDHPRLSDAADYLLGEV 1570 Query: 1540 LGLGEQTNVRQ----ASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVP 1595 LGL EQ AS + RTDDPIA+VAVSCRFPGAPDPE+FW+LL+GGVDAIREVP Sbjct: 1571 LGLSEQAPAESRPALASLASERTDDPIAIVAVSCRFPGAPDPEAFWDLLSGGVDAIREVP 1630 Query: 1596 EDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETV 1655 EDR+DIDEFYDPDPD GKTYTR PEFFGISPREAVWIEPQQRLMLETV Sbjct: 1631 EDRFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETV 1690 Query: 1656 WEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVA 1715 WEG+ERAG +P+DLRGSRTGVF GVAANEYAHLLS+ESI+KIEPHFITGNALNAISGRVA Sbjct: 1691 WEGIERAGLSPADLRGSRTGVFVGVAANEYAHLLSSESIEKIEPHFITGNALNAISGRVA 1750 Query: 1716 FALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARM 1775 FALG EGPAVAVDTACSSALVAVHQA QAL SGDCDLA+AGGVNVLLSPVTVVAASRARM Sbjct: 1751 FALGLEGPAVAVDTACSSALVAVHQAVQALHSGDCDLAVAGGVNVLLSPVTVVAASRARM 1810 Query: 1776 LSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLT 1835 LSPVGRCKTFDASADGYVRSEGCG+L+LKRLSDAVRDGDRVCAVIP ++VNQDGASSGLT Sbjct: 1811 LSPVGRCKTFDASADGYVRSEGCGILLLKRLSDAVRDGDRVCAVIPGTAVNQDGASSGLT 1870 Query: 1836 VPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPL 1895 VPNGGAQQRLI+ L RAGL+G DVDYLEAHGTGTPLGDPIEVQ PL Sbjct: 1871 VPNGGAQQRLIKTALTRAGLTGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGASRDADRPL 1930 Query: 1896 LMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPV 1955 LMGSVK+NIGH ESASGAAGLIKVVLSLQHGVLPQSLHF+NPSPHIPWD+LPVRV+DE V Sbjct: 1931 LMGSVKSNIGHLESASGAAGLIKVVLSLQHGVLPQSLHFDNPSPHIPWDSLPVRVVDEAV 1990 Query: 1956 PWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSP-QVL 2014 PWQ NGR RRAGVSSFGFTGTNAHVLVEEAP TDD P VL Sbjct: 1991 PWQPNGRPRRAGVSSFGFTGTNAHVLVEEAP---------QAPVSEDQEYDTDDQPVHVL 2041 Query: 2015 ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXX 2074 LSARSPEALV LARRYD WL A P D+A VC TAG GRSHFE+RAA+VVDSV Sbjct: 2042 PLSARSPEALVALARRYDSWLGAHPDADLAGVCFTAGTGRSHFEHRAAMVVDSVASARQG 2101 Query: 2075 XXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAV 2134 T GVVRGEH +RPTTAWLFTGQGSQYP MARELFD +PVFA+TV +CA+AV Sbjct: 2102 LADLADNRTRPGVVRGEHTNRPTTAWLFTGQGSQYPRMARELFDAEPVFAETVTRCADAV 2161 Query: 2135 ADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVG 2194 MLP PLL+VLFA DRETA+ L+HTS+AQPALFAVEMGLARLWQSW + PDVVLGHSVG Sbjct: 2162 DGMLPLPLLEVLFAADRETAERLRHTSYAQPALFAVEMGLARLWQSWGVTPDVVLGHSVG 2221 Query: 2195 QYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGA 2254 QYAAACVAGVFSL+DGARLMAERGRMFGSLPEGGRMVA+FADA+ VEQ+AGEF RVSVGA Sbjct: 2222 QYAAACVAGVFSLEDGARLMAERGRMFGSLPEGGRMVAIFADAKQVEQIAGEFARVSVGA 2281 Query: 2255 YNGPNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXX 2314 YNGPNTVLSGPGEDLE+IV RF DEGIRCTWL TSHAFHSELLDPVLD Sbjct: 2282 YNGPNTVLSGPGEDLEQIVARFADEGIRCTWLETSHAFHSELLDPVLDEFESYAAQFEFA 2341 Query: 2315 XPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVL 2374 PT+PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVL Sbjct: 2342 APTMPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVL 2401 Query: 2375 TGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVEL 2434 TGAAVQ+WPEH+AAPRA+ASLRKGV DRRQIADALA+AYVGG RPDFAA+ QP +EL Sbjct: 2402 TGAAVQIWPEHLAAPRAIASLRKGVGDRRQIADALAAAYVGGLRPDFAALQGQPHHRLEL 2461 Query: 2435 PTYPFQRRRFWPKASSIAVDGGTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIY 2494 PTYPFQRRRFWPK SSI VD G A SGILGS KDLASGDT+Y SRLSVKSQPWL+DHVIY Sbjct: 2462 PTYPFQRRRFWPKTSSITVD-GPATSGILGSAKDLASGDTVYASRLSVKSQPWLSDHVIY 2520 Query: 2495 GTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQI 2554 GTVVVPGATYAAMALAAVGTPAR+KDVFFYEPIILPEK+SREVQLTLH G FQ+ Sbjct: 2521 GTVVVPGATYAAMALAAVGTPARVKDVFFYEPIILPEKSSREVQLTLHMLGDGE-QKFQV 2579 Query: 2555 HSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADL 2614 HSR YG R A+WSLNAEGTV D A Q DPVDE IER RMRPQ+LFETFAD+ Sbjct: 2580 HSRSYGVRDAEWSLNAEGTVVRGVDD---APVSQDDPVDEAIERCNRMRPQELFETFADM 2636 Query: 2615 ELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXX 2674 ELAWGPTWSGSLKSLWLGDGEA+GD+LVGAELAEQLGSEP+HPVLMDLCTGV Sbjct: 2637 ELAWGPTWSGSLKSLWLGDGEAIGDVLVGAELAEQLGSEPIHPVLMDLCTGVAFPAFPAL 2696 Query: 2675 XXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALG 2734 EQGV+DLFLPLRYGQVT+ EKMPRRFYCRA+WH S LDSETQVF+L+F+ GR LG Sbjct: 2697 LAAEQGVSDLFLPLRYGQVTVQEKMPRRFYCRAKWHHSELDSETQVFDLDFISRDGRPLG 2756 Query: 2735 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPP---PSADDAVGTWLIAGFDELA 2791 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVP P P+A + G WLIAGFDELA Sbjct: 2757 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPLPAVDPAAPN--GNWLIAGFDELA 2814 Query: 2792 AKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXX 2851 VPGC+P DR TD + LG++L+QAH RG FSGVVWR A P K Sbjct: 2815 DAVPGCIPFDRTTDPEPLGQLLTQAHERGMAFSGVVWRAAAP--KPDESSADVAARIETE 2872 Query: 2852 ITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALH 2911 I NLLSAVHA Q VKLPGGLWIVTE VACESGEPVDPVQAALWGFGRTTINEEPAL Sbjct: 2873 IANLLSAVHAVQRGEVKLPGGLWIVTERAVACESGEPVDPVQAALWGFGRTTINEEPALR 2932 Query: 2912 CRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFV 2971 C+LVDCDGS EAV+ P + EPE+A+RQGKLLASRLL WARSGHLT+PR D+V Sbjct: 2933 CKLVDCDGSPEAVEALSALLTTP-VDEPELALRQGKLLASRLLHWARSGHLTVPRSTDYV 2991 Query: 2972 LAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFA 3031 LAPTERGAIDNLRLTET+VP P EGYVQV+VEAAGLNFRDVLNVLGLYPGDPGPIGGDFA Sbjct: 2992 LAPTERGAIDNLRLTETEVPPPAEGYVQVKVEAAGLNFRDVLNVLGLYPGDPGPIGGDFA 3051 Query: 3032 GTVTQLGAGVSG----------LEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEA 3081 G VTQLG GV LE+GQRVYG MQGAF+SRFNVPAQ LAPIPDG+GAVEA Sbjct: 3052 GVVTQLGDGVGSGRAERRDGIKLEVGQRVYGFMQGAFSSRFNVPAQLLAPIPDGVGAVEA 3111 Query: 3082 ATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRST 3141 ATIPAAALT RLAFDWAQL+PGD+VLIHAASGGVGLAAIQ+AQQ GA VFATAST+KR+T Sbjct: 3112 ATIPAAALTARLAFDWAQLEPGDRVLIHAASGGVGLAAIQLAQQHGAVVFATASTYKRAT 3171 Query: 3142 LRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIA 3201 LR++GV+YVYDSR+TDFADQILADT+GAGVDVVLNSLT+ GFVEAT++ATAQ GRFAEIA Sbjct: 3172 LRKMGVEYVYDSRSTDFADQILADTDGAGVDVVLNSLTNEGFVEATVRATAQNGRFAEIA 3231 Query: 3202 KRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYP 3261 KRDIW+HEQMA ARPDI+YEIVALDTV EP+RIR LL EVSDG+ +GEW PLPAEIYP Sbjct: 3232 KRDIWTHEQMAAARPDISYEIVALDTVTIQEPERIRGLLGEVSDGLGKGEWAPLPAEIYP 3291 Query: 3262 ITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGD 3321 +TEAR+AFRRMQQARHIGKI DRSYLITGGLGAIGLHTA+YLAQLGAGD Sbjct: 3292 LTEARAAFRRMQQARHIGKIVVQMPSPLQPRPDRSYLITGGLGAIGLHTASYLAQLGAGD 3351 Query: 3322 IVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAH 3381 IVLTSRR+PD Q+ IDEITERH+CRIHT+AADVGDE+QV +LL RIRAELPPLAG+AH Sbjct: 3352 IVLTSRREPDADTQQVIDEITERHRCRIHTFAADVGDESQVEELLERIRAELPPLAGVAH 3411 Query: 3382 LAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQA 3441 LAGVLDDALLS Q+ ERFRTTLAPKA+GA H PGQA Sbjct: 3412 LAGVLDDALLSQQSVERFRTTLAPKAFGAYHLDHLTRDDDLDFFIVSSSVSSLFGSPGQA 3471 Query: 3442 NYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAAL 3501 NYATANA+LDGLVA+RRA GL ATG+NFGPW QGGMASSEAATANI+AQGL+PL+PSAAL Sbjct: 3472 NYATANALLDGLVARRRAHGLPATGVNFGPWAQGGMASSEAATANISAQGLVPLEPSAAL 3531 Query: 3502 HALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEI 3561 ALAEV+ANG+ QATV+KANWQRAAKVLG++RPP+LDLVLPSAAGE TGDSELL+QL EI Sbjct: 3532 SALAEVVANGTAQATVIKANWQRAAKVLGASRPPLLDLVLPSAAGEVTGDSELLRQLQEI 3591 Query: 3562 PIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTI 3621 P+ QRAGFVTEFLQREVQNFLRLA PPAASSRFLDLGTDSLMAIELRNRLHSQFGG FTI Sbjct: 3592 PVAQRAGFVTEFLQREVQNFLRLAQPPAASSRFLDLGTDSLMAIELRNRLHSQFGGAFTI 3651 Query: 3622 NATAVFDYPTIGGLAEYLVGQLPDAEAPETA 3652 NATAVFDYPTIGGLAEYLVGQLPDAE+P A Sbjct: 3652 NATAVFDYPTIGGLAEYLVGQLPDAESPPAA 3682 Score = 1031 bits (2665), Expect = 0.0 Identities = 522/903 (57%), Positives = 630/903 (69%), Gaps = 11/903 (1%) Query: 1544 EQTNVRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDE 1603 E TN +++ + A+V + RFPGA D + FW+LL G +AI EVP+DRW++DE Sbjct: 14 EDTNGMESAAYPHVPANRFAIVGYAARFPGAQDADEFWDLLRDGREAISEVPQDRWNVDE 73 Query: 1604 FYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAG 1663 F+DP+P PGK TR FFG+S RE ++PQ RL+LET W +E +G Sbjct: 74 FFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSG 133 Query: 1664 YAPSDLRGSRTGVFTGVAANEYAHLLSAE-SIDKIEPHFITGNALNAISGRVAFALGFEG 1722 AP+DL S TGVF G+A ++Y + S E S +IE + G + A +GR+++ LG +G Sbjct: 134 TAPTDLANSNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQG 193 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PAVAVDTACSS+LVA+HQACQALQ G+CDLALAGG NVLL+P T++ S A ML+P GRC Sbjct: 194 PAVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRC 253 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 KTFDA+ADGYVR EGCGV+V+KRL DA+RDGDR+ AVI S++NQDGAS GLTVPNG AQ Sbjct: 254 KTFDAAADGYVRGEGCGVIVIKRLEDALRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQ 313 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QR+I L RAG+ DV YLEAHGTGT LGDPIE Q PLL+GS KT Sbjct: 314 QRVITDALKRAGVRAGDVGYLEAHGTGTSLGDPIEAQAAGEVLGAGREPSRPLLIGSAKT 373 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGH E+A+G AG+IKV+LSL+H LP+ L+F PSPHIPWD L V+V+ E PW+ NGR Sbjct: 374 NIGHLEAAAGIAGVIKVILSLEHETLPKHLNFTTPSPHIPWDRLAVKVVTESTPWERNGR 433 Query: 1963 VRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPE 2022 R AGVSSFGF GTNAHV++EEAP + +L LSAR+P Sbjct: 434 PRIAGVSSFGFAGTNAHVILEEAPES---------TVTPAATPEPGERFSLLPLSARTPS 484 Query: 2023 ALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXX 2082 ALV +A RY W++ P +ADVC TA R+H E RAALVVDS Sbjct: 485 ALVRIADRYRSWMTTHPEATLADVCFTASTARAHLEQRAALVVDSRESAVELLGALAEDR 544 Query: 2083 TPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPL 2142 G+VRGE P TAWLFTGQGSQYPGMARELFDT+PVFA+T++QCA AVAD+L +PL Sbjct: 545 PAPGLVRGESHDTPKTAWLFTGQGSQYPGMARELFDTEPVFAETMKQCAAAVADVLEKPL 604 Query: 2143 LDVLF-ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACV 2201 LDV+F A E A+ L+ TS+AQPALFAVEMGLARLWQSW EPDVVLGHSVGQYAAACV Sbjct: 605 LDVIFDAHGPEAAETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACV 664 Query: 2202 AGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTV 2261 AGV L+DGARLMAERGR+FGSLP GGRMVAVF AE VE + E+PR+SV AYNG NTV Sbjct: 665 AGVLGLEDGARLMAERGRLFGSLPAGGRMVAVFTAAERVENITDEYPRLSVAAYNGANTV 724 Query: 2262 LSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLV 2321 LSGP DLE+ V +G+RC WL TSHAFHS LLDP+LD P L+ Sbjct: 725 LSGPAGDLEKAVATLAADGVRCDWLDTSHAFHSALLDPILDEFESYAQQIEYAAPQRVLI 784 Query: 2322 CNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQV 2381 NRTGA L LD YWRRH+RQPV+FA+SVRT+A L C VL+EIGP+PVLT AA+ Sbjct: 785 DNRTGAALGWSAKLDGTYWRRHARQPVEFAKSVRTLAELNCKVLLEIGPRPVLTAAALSA 844 Query: 2382 WPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQR 2441 WP+ APRA+ASLR+ AD RQI +ALA AYV GHRPDFAA+ R ++LPTYPF+ Sbjct: 845 WPDPATAPRAIASLRRNTADHRQITEALADAYVLGHRPDFAAIQRPDAHKLDLPTYPFEH 904 Query: 2442 RRF 2444 R++ Sbjct: 905 RQY 907 >tr|A1U9G3|A1U9G3_MYCSK Tax_Id=189918 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium sp.] Length = 3693 Score = 5537 bits (14363), Expect = 0.0 Identities = 2833/3693 (76%), Positives = 3087/3693 (83%), Gaps = 68/3693 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M SA +P P FAI+GYAARFPGA A+E+W LLRDGREAIS+VP+DRW+++EFFDP+ Sbjct: 19 MESAAYPHVPANRFAIVGYAARFPGAQDADEFWDLLRDGREAISEVPQDRWNVDEFFDPE 78 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFVDDVTGFDAPFFGMS REVRLMDPQHR+L+ETAWRAVEHSG APT Sbjct: 79 PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGTAPTD 138 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LANSNTGVFVGLATHDYLGMASDEL+YPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV Sbjct: 139 LANSNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 198 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQAL+L ECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA Sbjct: 199 DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 258 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGV+V+KRLEDA+RDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI Sbjct: 259 AADGYVRGEGCGVIVIKRLEDALRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIT 318 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DALKRAG+R DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGR P PLLIGSAKTNIGHL Sbjct: 319 DALKRAGVRAGDVGYLEAHGTGTSLGDPIEAQAAGEVLGAGREPSRPLLIGSAKTNIGHL 378 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LE+ETLPKHLNF TPSPHIPW+RL ++VV E+ PW+RNG+PRIAG Sbjct: 379 EAAAGIAGVIKVILSLEHETLPKHLNFTTPSPHIPWDRLAVKVVTESTPWERNGRPRIAG 438 Query: 421 VSSFGFAGTNAHVILEEAP-AVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDW 479 VSSFGFAGTNAHVILEEAP + TPA T E R+S+LPLSARTP ALVR+A YR W Sbjct: 439 VSSFGFAGTNAHVILEEAPESTVTPAATP--EPGERFSLLPLSARTPAALVRIADRYRSW 496 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 + HP+A LADV TA TARAHLEQRAALVV+SRESA+ELLGALADDRPAPGLVRGESH+ Sbjct: 497 MTTHPEATLADVCFTASTARAHLEQRAALVVDSRESAVELLGALADDRPAPGLVRGESHD 556 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 PKTAWLFTGQGSQYPGMARELFDTEPVFAET+++CA AVAD+LEKPLLDVIFDA Sbjct: 557 TPKTAWLFTGQGSQYPGMARELFDTEPVFAETMKQCAAAVADVLEKPLLDVIFDAH--GP 614 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 + LR T+YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQY+AACVAGV +EDGA Sbjct: 615 EAAETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLGLEDGA 674 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLES 719 RL+AERGRLFGSLPAGGRM AVFTA ER E +TDEYP LSVAAYNGANTVLSGPA DLE Sbjct: 675 RLMAERGRLFGSLPAGGRMVAVFTAAERVENITDEYPRLSVAAYNGANTVLSGPAGDLEK 734 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 AVATL ADG+RCDWLDTSHAFHSALLDPILD+FES+AQ++EY PQR+LIDNRTG+ALG Sbjct: 735 AVATLAADGIRCDWLDTSHAFHSALLDPILDEFESYAQQIEYAAPQRVLIDNRTGAALGW 794 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 S +LDG YWRRHARQPVEFAKSVRTLA++NC+VLLEIGPRPVLTA AL+AWPDPAT P+ Sbjct: 795 SAKLDGTYWRRHARQPVEFAKSVRTLAELNCKVLLEIGPRPVLTAAALSAWPDPATAPRA 854 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 +ASLR TADHRQITEA+A AY GH PDF A ++PDA KLDLPTYPFEHRQ+ F DN+A Sbjct: 855 IASLRRNTADHRQITEALADAYVLGHRPDFAAIQRPDAHKLDLPTYPFEHRQYSFRDNQA 914 Query: 900 IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQR 959 +R Q A RT+AV LLEDG+IEELAAL+ D QT VL+KLAA+HNQQR Sbjct: 915 -ERPEQ-AGPPIHQAARTEAVGLLEDGRIEELAALLGDTDGDRQTFDVLSKLAAQHNQQR 972 Query: 960 STHVDPDARYEIRWDXXXXXXXXXXXXXD-WILVGDDTAAVLEFADALTAGGHRHQIVAL 1018 ++ D RYEIRW+ WI+VGDDT A DA+TA G RH++V Sbjct: 973 TSQSITDDRYEIRWEELTTASPAATGEPSTWIIVGDDTDAARPLIDAVTARGDRHRLVGS 1032 Query: 1019 PGSDADEAQLVDTLRA------ASAGELYVVHIAAGDGAAAP-MRDLLRVQHRTLGGLRR 1071 P SDADEA L D LRA A G + ++HIAA D AP MR LL +QHR LG RR Sbjct: 1033 PVSDADEASLADALRASVDDASAPGGAVRILHIAALDATTAPSMRTLLSMQHRILGRTRR 1092 Query: 1072 LFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADL-- 1129 LF A LR+PIWL+TR QRVT TDTV P+QS LWGFGRAA+LELPH+WGGLADL Sbjct: 1093 LFHAVTTTGLRTPIWLITRGAQRVTATDTVAPDQSALWGFGRAASLELPHLWGGLADLPT 1152 Query: 1130 --SGADTEWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT 1184 ++ EW RL+ RI +PR EDQ+ALR AV+ PRLVRRTG+PS PL +R D T Sbjct: 1153 GPGASEDEWSRLLDRIAAPRHSDVTEDQVALRDGAVHVPRLVRRTGQPSGAPLRLRSDAT 1212 Query: 1185 YLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADV 1244 YLVTGGLGAIGLE+AGYLA+HGAG++VLTSRR P +++ C +RV TADV Sbjct: 1213 YLVTGGLGAIGLEIAGYLAAHGAGNIVLTSRRAPGDAAQQRIDALRDKFGCAIRVATADV 1272 Query: 1245 ADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDD----AEVDRVFAGKVWGAWH 1300 ADAHDVARL+ V AELPPLAGIVHAAGEIGTT LS +DD AEVDRVFAGKVWGAWH Sbjct: 1273 ADAHDVARLLAGVQAELPPLAGIVHAAGEIGTTALSAMDDESQQAEVDRVFAGKVWGAWH 1332 Query: 1301 LSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFG 1360 LSEA DL+ LDFF+STSSIASVWGGFGQTAYGAANAFLDGLAWRLRE+G+ A SVNFG Sbjct: 1333 LSEAAVDLQ--LDFFISTSSIASVWGGFGQTAYGAANAFLDGLAWRLREQGIAATSVNFG 1390 Query: 1361 PWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGP-VQGVVAKIDWSRFLPLYQQA 1419 PW+AGMADAESRARLEQRGVRTL PA+ALAG+ADVVAGP QGV+A+IDW+RFLPLYQQA Sbjct: 1391 PWSAGMADAESRARLEQRGVRTLDPADALAGLADVVAGPATQGVIARIDWARFLPLYQQA 1450 Query: 1420 GRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT 1479 GRRAFL+ELE E LVE+L+ APVQQRK L+T+YLR+AVAEVT Sbjct: 1451 GRRAFLTELEREAPVASTDAAPAVTASGKTPLVERLSGAPVQQRKKLLTDYLRDAVAEVT 1510 Query: 1480 RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEV 1539 RVD+ EIR++AGFFDLGMDSLMAVELRRR+EQGVGK+IPVTLVMDHPRLSDAADYLL EV Sbjct: 1511 RVDSAEIREDAGFFDLGMDSLMAVELRRRLEQGVGKEIPVTLVMDHPRLSDAADYLLGEV 1570 Query: 1540 LGLGEQTNVRQ----ASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVP 1595 LGL EQ AS + RTDDPIA+VAVSCRFPGAPDPE+FW+LL+GGVDAIREVP Sbjct: 1571 LGLAEQAPAESRPALASLASERTDDPIAIVAVSCRFPGAPDPEAFWDLLSGGVDAIREVP 1630 Query: 1596 EDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETV 1655 EDR+DIDEFYDPDPD GKTYTR PEFFGISPREAVWIEPQQRLMLETV Sbjct: 1631 EDRFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETV 1690 Query: 1656 WEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVA 1715 WEG+ERAG +P+DLRGSRTGVF GVAANEYAHLLS+ESI+KIEPHFITGNALNAISGRVA Sbjct: 1691 WEGIERAGLSPADLRGSRTGVFVGVAANEYAHLLSSESIEKIEPHFITGNALNAISGRVA 1750 Query: 1716 FALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARM 1775 FALG EGPAVAVDTACSSALVAVHQA QAL SGDCDLA+AGGVNVLLSPVTVVAASRARM Sbjct: 1751 FALGLEGPAVAVDTACSSALVAVHQAVQALHSGDCDLAVAGGVNVLLSPVTVVAASRARM 1810 Query: 1776 LSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLT 1835 LSPVGRCKTFDASADGYVRSEGCG+LVLKRLSDAVRDGDRVCAVIP ++VNQDGASSGLT Sbjct: 1811 LSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIPGTAVNQDGASSGLT 1870 Query: 1836 VPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPL 1895 VPNGGAQQRLI+ L RAGL+G DVDYLEAHGTGTPLGDPIEVQ PL Sbjct: 1871 VPNGGAQQRLIKTALTRAGLTGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGASRDADRPL 1930 Query: 1896 LMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPV 1955 LMGSVK+NIGH ESASGAAGLIKVVLSLQHGVLPQSLHF+NPSPHIPWD+LPVRV+DE V Sbjct: 1931 LMGSVKSNIGHLESASGAAGLIKVVLSLQHGVLPQSLHFDNPSPHIPWDSLPVRVVDEAV 1990 Query: 1956 PWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSP-QVL 2014 PWQ NGR RRAGVSSFGFTGTNAHVLVEEAP TDD P VL Sbjct: 1991 PWQPNGRPRRAGVSSFGFTGTNAHVLVEEAP---------QAPVSEDQESDTDDQPVHVL 2041 Query: 2015 ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXX 2074 LSARSPEALV LARRYD WL A P D+A VC TAG GRSHFE+RAA+VVDSV Sbjct: 2042 PLSARSPEALVALARRYDSWLGAHPDADLAGVCFTAGTGRSHFEHRAAMVVDSVASARQG 2101 Query: 2075 XXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAV 2134 T GVVRGEH +RPTTAWLFTGQGSQYP MARELFD +PVFA+TV +CA+AV Sbjct: 2102 LADLADNRTRPGVVRGEHTNRPTTAWLFTGQGSQYPRMARELFDAEPVFAETVTRCADAV 2161 Query: 2135 ADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVG 2194 MLP PLL+VLFA DRETA+ L+HTS+AQPALFAVEMGLARLWQSW + PDVVLGHSVG Sbjct: 2162 DGMLPLPLLEVLFAADRETAERLRHTSYAQPALFAVEMGLARLWQSWGVTPDVVLGHSVG 2221 Query: 2195 QYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGA 2254 QYAAACVAGVFSL+DGARLMAERGRMFGSLPEGGRMVA+FADA+ VEQ+AGEF RVSVGA Sbjct: 2222 QYAAACVAGVFSLEDGARLMAERGRMFGSLPEGGRMVAIFADAKQVEQIAGEFARVSVGA 2281 Query: 2255 YNGPNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXX 2314 YNGPNTVLSGPGEDLE+IV RF DEGIRCTWL TSHAFHSELLDPVLD Sbjct: 2282 YNGPNTVLSGPGEDLEQIVARFADEGIRCTWLETSHAFHSELLDPVLDEFESYAAQFEFA 2341 Query: 2315 XPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVL 2374 PT+P+VCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVA LGCSVLMEIGPQPVL Sbjct: 2342 APTMPVVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVATLGCSVLMEIGPQPVL 2401 Query: 2375 TGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVEL 2434 TGAAVQ+WPEH+AAPRA+ASLRKGV DRRQIADALA+AYVGG RPDFAA+ QP +EL Sbjct: 2402 TGAAVQIWPEHLAAPRAIASLRKGVGDRRQIADALAAAYVGGLRPDFAALQGQPHHRLEL 2461 Query: 2435 PTYPFQRRRFWPKASSIAVDGGTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIY 2494 PTYPFQRRRFWPK SSI VD G A SGILGS KDLASGDT+YTSRLSVKSQPWL+DHVIY Sbjct: 2462 PTYPFQRRRFWPKTSSITVD-GPATSGILGSAKDLASGDTVYTSRLSVKSQPWLSDHVIY 2520 Query: 2495 GTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQI 2554 GTVVVPGATYAAMALAAVGTPAR+KDVFFYEPIILPEK+SREVQLTLH G FQ+ Sbjct: 2521 GTVVVPGATYAAMALAAVGTPARVKDVFFYEPIILPEKSSREVQLTLHILGDGE-QKFQV 2579 Query: 2555 HSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADL 2614 HSR YG R A+WSLNAEGTV D A Q DPVDE IER RMRPQ+LFETFAD+ Sbjct: 2580 HSRSYGVRDAEWSLNAEGTVVRGVDD---APVSQDDPVDEAIERCNRMRPQELFETFADM 2636 Query: 2615 ELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXX 2674 ELAWGPTWSGSLKSLWLGDGEA+GD+LVGAELAEQLGSEP+HPVLMDLCTGV Sbjct: 2637 ELAWGPTWSGSLKSLWLGDGEAIGDVLVGAELAEQLGSEPIHPVLMDLCTGVAFPAFPAL 2696 Query: 2675 XXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALG 2734 EQGV+DLFLPLRYGQVT+ EKMPRRFYCRA+WH S LDSETQVF+L+F+ GR LG Sbjct: 2697 LAAEQGVSDLFLPLRYGQVTVQEKMPRRFYCRAKWHHSELDSETQVFDLDFISRDGRPLG 2756 Query: 2735 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPP---PSADDAVGTWLIAGFDELA 2791 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVP P P+A + G WLIAGFDELA Sbjct: 2757 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPLPAVDPAAPN--GNWLIAGFDELA 2814 Query: 2792 AKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXX 2851 A VPGC+P DR TD + LG++L+QAH RG FSGVVWR A P K Sbjct: 2815 ASVPGCIPFDRTTDPEPLGQLLTQAHERGMAFSGVVWRAAAP--KPDESSADVAARIETE 2872 Query: 2852 ITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALH 2911 I NLLSAVHA Q VKLPGGLWIVTE VACESGEPVDPVQAALWGFGRTTINEEPAL Sbjct: 2873 IANLLSAVHAVQRGEVKLPGGLWIVTERAVACESGEPVDPVQAALWGFGRTTINEEPALR 2932 Query: 2912 CRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFV 2971 C+LVDCDGS EAV+ P + EPE+A+RQGKLLASRLL WARSGHLT+PR D+V Sbjct: 2933 CKLVDCDGSPEAVEALSALLTTP-VDEPELALRQGKLLASRLLHWARSGHLTVPRSTDYV 2991 Query: 2972 LAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFA 3031 LAPTERGAIDNLRLTET+VP P EGYVQV VEAAGLNFRDVLNVLGLYPGDPGPIGGDFA Sbjct: 2992 LAPTERGAIDNLRLTETEVPPPAEGYVQVEVEAAGLNFRDVLNVLGLYPGDPGPIGGDFA 3051 Query: 3032 GTVTQLGAGVSG----------LEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEA 3081 G VTQLG GV LE+GQRVYG MQGAF+SRFNVPAQ LAPIPDG+GAVEA Sbjct: 3052 GVVTQLGDGVGSGRAERRDGIKLEVGQRVYGFMQGAFSSRFNVPAQLLAPIPDGVGAVEA 3111 Query: 3082 ATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRST 3141 ATIPAAALT RLAFDWAQL+PGD+VLIHAASGGVGLAAIQ+AQQ GA VFATAST+KR+T Sbjct: 3112 ATIPAAALTARLAFDWAQLEPGDRVLIHAASGGVGLAAIQLAQQHGAVVFATASTYKRAT 3171 Query: 3142 LRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIA 3201 LR++GV+YVYDSR+TDFADQILADT+GAGVDVVLNSLT+ GFVEAT++ATAQ GRFAEIA Sbjct: 3172 LRKMGVEYVYDSRSTDFADQILADTDGAGVDVVLNSLTNEGFVEATVRATAQNGRFAEIA 3231 Query: 3202 KRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYP 3261 KRDIW+HEQMA ARPDI+YEIVALDTV EP+RIR LL EVSDG+ +GEW PLPAEIYP Sbjct: 3232 KRDIWTHEQMAAARPDISYEIVALDTVTIQEPERIRGLLGEVSDGLGKGEWAPLPAEIYP 3291 Query: 3262 ITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGD 3321 +TEAR+AFRRMQQARHIGKI DRSYLITGGLGAIGLHTA+YLAQLGAGD Sbjct: 3292 LTEARAAFRRMQQARHIGKIVVQMPSPLQPRPDRSYLITGGLGAIGLHTASYLAQLGAGD 3351 Query: 3322 IVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAH 3381 IVLTSRR+PD Q+ IDEIT+RH+CRIHT+AADVGDE+QV +LL RIRAELPPLAG+AH Sbjct: 3352 IVLTSRREPDADTQQVIDEITDRHRCRIHTFAADVGDESQVEELLERIRAELPPLAGVAH 3411 Query: 3382 LAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQA 3441 LAGVLDDALLS Q+ ERFRTTLAPKA+GA H PGQA Sbjct: 3412 LAGVLDDALLSQQSVERFRTTLAPKAFGAYHLDHLTRDDDLDFFIVSSSVSSLFGSPGQA 3471 Query: 3442 NYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAAL 3501 NYATANA+LDGLVA+RRA GL ATG+NFGPW QGGMASSEAATANI+AQGL+PL+PSAAL Sbjct: 3472 NYATANALLDGLVARRRAHGLPATGVNFGPWAQGGMASSEAATANISAQGLVPLEPSAAL 3531 Query: 3502 HALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEI 3561 ALAEV+ANG+ QATV+KANWQRAAKVLG++RPP+LDLVLPSAAGE TGDSELL+QL EI Sbjct: 3532 SALAEVVANGTAQATVIKANWQRAAKVLGASRPPLLDLVLPSAAGEVTGDSELLRQLQEI 3591 Query: 3562 PIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTI 3621 P+ QRAGFVTEFLQREVQNFLRLA PPAASSRFLDLGTDSLMAIELRNRLHSQFGG FTI Sbjct: 3592 PVAQRAGFVTEFLQREVQNFLRLAQPPAASSRFLDLGTDSLMAIELRNRLHSQFGGAFTI 3651 Query: 3622 NATAVFDYPTIGGLAEYLVGQLPDAEAP--ETA 3652 NATAVFDYPTIGGLAEYLVGQLPDAE+P ETA Sbjct: 3652 NATAVFDYPTIGGLAEYLVGQLPDAESPAAETA 3684 Score = 1031 bits (2665), Expect = 0.0 Identities = 523/903 (57%), Positives = 630/903 (69%), Gaps = 11/903 (1%) Query: 1544 EQTNVRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDE 1603 E TN +++ + A+V + RFPGA D + FW+LL G +AI EVP+DRW++DE Sbjct: 14 EDTNGMESAAYPHVPANRFAIVGYAARFPGAQDADEFWDLLRDGREAISEVPQDRWNVDE 73 Query: 1604 FYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAG 1663 F+DP+P PGK TR FFG+S RE ++PQ RL+LET W +E +G Sbjct: 74 FFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSG 133 Query: 1664 YAPSDLRGSRTGVFTGVAANEYAHLLSAE-SIDKIEPHFITGNALNAISGRVAFALGFEG 1722 AP+DL S TGVF G+A ++Y + S E S +IE + G + A +GR+++ LG +G Sbjct: 134 TAPTDLANSNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQG 193 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PAVAVDTACSS+LVA+HQACQALQ G+CDLALAGG NVLL+P T++ S A ML+P GRC Sbjct: 194 PAVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRC 253 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 KTFDA+ADGYVR EGCGV+V+KRL DA+RDGDR+ AVI S++NQDGAS GLTVPNG AQ Sbjct: 254 KTFDAAADGYVRGEGCGVIVIKRLEDALRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQ 313 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QR+I L RAG+ DV YLEAHGTGT LGDPIE Q PLL+GS KT Sbjct: 314 QRVITDALKRAGVRAGDVGYLEAHGTGTSLGDPIEAQAAGEVLGAGREPSRPLLIGSAKT 373 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGH E+A+G AG+IKV+LSL+H LP+ L+F PSPHIPWD L V+V+ E PW+ NGR Sbjct: 374 NIGHLEAAAGIAGVIKVILSLEHETLPKHLNFTTPSPHIPWDRLAVKVVTESTPWERNGR 433 Query: 1963 VRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPE 2022 R AGVSSFGF GTNAHV++EEAP + +L LSAR+P Sbjct: 434 PRIAGVSSFGFAGTNAHVILEEAPES---------TVTPAATPEPGERFSLLPLSARTPA 484 Query: 2023 ALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXX 2082 ALV +A RY W++ P +ADVC TA R+H E RAALVVDS Sbjct: 485 ALVRIADRYRSWMTTHPEATLADVCFTASTARAHLEQRAALVVDSRESAVELLGALADDR 544 Query: 2083 TPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPL 2142 G+VRGE P TAWLFTGQGSQYPGMARELFDT+PVFA+T++QCA AVAD+L +PL Sbjct: 545 PAPGLVRGESHDTPKTAWLFTGQGSQYPGMARELFDTEPVFAETMKQCAAAVADVLEKPL 604 Query: 2143 LDVLF-ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACV 2201 LDV+F A E A+ L+ TS+AQPALFAVEMGLARLWQSW EPDVVLGHSVGQYAAACV Sbjct: 605 LDVIFDAHGPEAAETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACV 664 Query: 2202 AGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTV 2261 AGV L+DGARLMAERGR+FGSLP GGRMVAVF AE VE + E+PR+SV AYNG NTV Sbjct: 665 AGVLGLEDGARLMAERGRLFGSLPAGGRMVAVFTAAERVENITDEYPRLSVAAYNGANTV 724 Query: 2262 LSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLV 2321 LSGP DLE+ V +GIRC WL TSHAFHS LLDP+LD P L+ Sbjct: 725 LSGPAGDLEKAVATLAADGIRCDWLDTSHAFHSALLDPILDEFESYAQQIEYAAPQRVLI 784 Query: 2322 CNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQV 2381 NRTGA L LD YWRRH+RQPV+FA+SVRT+A L C VL+EIGP+PVLT AA+ Sbjct: 785 DNRTGAALGWSAKLDGTYWRRHARQPVEFAKSVRTLAELNCKVLLEIGPRPVLTAAALSA 844 Query: 2382 WPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQR 2441 WP+ APRA+ASLR+ AD RQI +ALA AYV GHRPDFAA+ R ++LPTYPF+ Sbjct: 845 WPDPATAPRAIASLRRNTADHRQITEALADAYVLGHRPDFAAIQRPDAHKLDLPTYPFEH 904 Query: 2442 RRF 2444 R++ Sbjct: 905 RQY 907 >tr|A5A9S2|A5A9S2_MYCCH Tax_Id=1774 (pks)SubName: Full=Pks protein;[Mycobacterium chelonae] Length = 3707 Score = 5495 bits (14254), Expect = 0.0 Identities = 2784/3678 (75%), Positives = 3075/3678 (83%), Gaps = 38/3678 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M SA+HP P P FAIIGYAARFPGAA+A+E+W +LR+GR+AIS+VP DRWD +EFFD + Sbjct: 1 MESADHPNNPAPRFAIIGYAARFPGAANADEFWDVLREGRDAISEVPADRWDADEFFDSE 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFVDDVTGFDAPFFGMS REVRLMDPQHR+L+E AWRAVEHSGIAPT Sbjct: 61 PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLEMAWRAVEHSGIAPTD 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LA +N GVFVGLATHDYLGMASDELT+PEIEAYMAIGTSNAAAAGRISYRLGLQGP+VAV Sbjct: 121 LAETNAGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQAL+L ECDLALAGGANVLLTPATMITFS+AHMLAPDG+CKTFDA Sbjct: 181 DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEG GV+V+KRLEDA+RDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA Sbjct: 241 AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DALKRAG+ P+DVGYLEAHGTGTSLGDPIEAQAAG G GRA +PLLIGSAKTNIGHL Sbjct: 301 DALKRAGVAPSDVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRAANDPLLIGSAKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LENE LP+H NF+ PSPHIPW+RLP+EVV+E W+RNG+PRIAG Sbjct: 361 EAAAGIAGVIKVVLSLENELLPQHRNFQNPSPHIPWDRLPVEVVKEATAWERNGRPRIAG 420 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTE-PVEDPRRYSVLPLSARTPEALVRLAGEYRDW 479 VSSFGFAGTNAHVILEEAP T E P R+S+LPLSARTP ALV++A +YR W Sbjct: 421 VSSFGFAGTNAHVILEEAPVAAEIETAEEPESTGDRFSILPLSARTPAALVQIADQYRSW 480 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 L HP+A LAD+ TAG RAHLE RAALVVNSRE+A+ELLGA+ADDRPAPGL RGESH+ Sbjct: 481 LNGHPEATLADLCFTAGVGRAHLEHRAALVVNSREAAVELLGAVADDRPAPGLGRGESHD 540 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 PKTAWLFTGQGSQYPGMARELFDTEPVFAET+++CA VAD+LEKPLLDVIFD D Sbjct: 541 TPKTAWLFTGQGSQYPGMARELFDTEPVFAETLKRCAAVVADVLEKPLLDVIFDVD--GP 598 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 D E+ LR T YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQY+AACVAGVF +EDGA Sbjct: 599 DAEATLRQTAYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVFSLEDGA 658 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLES 719 L+AERGRLFGSLPAGGRMAA+F A ER E LTD++PSLSVAAYNGANTVLSGPA+DLE Sbjct: 659 ALMAERGRLFGSLPAGGRMAAIFAAAERVESLTDDFPSLSVAAYNGANTVLSGPAQDLEK 718 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 AVA LVA+G+RCD+L+TSHAFHSALLDPILD+FE +A K Y+ PQRILIDNRTG+ALGR Sbjct: 719 AVAGLVAEGIRCDFLETSHAFHSALLDPILDEFEVYAGKFNYKTPQRILIDNRTGTALGR 778 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 S +LDGAYWRRHARQPVEFAKSVRTLADMNC+VL EIGP+PVLTA AL AWPDPAT P+ Sbjct: 779 SVKLDGAYWRRHARQPVEFAKSVRTLADMNCKVLFEIGPQPVLTAAALRAWPDPATAPRA 838 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 +ASLR TADHRQITEA A AY GHLPDF AFR ARKLDLPTYPFEHRQ+WFSD R Sbjct: 839 IASLRRNTADHRQITEAAADAYVLGHLPDFGAFRHGHARKLDLPTYPFEHRQYWFSDKRN 898 Query: 900 IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQR 959 D T + RT+AVRLLEDG+IEELA L+ G + D+QTL VL KLAA+HNQQR Sbjct: 899 ADNRDATKQQQPASGSRTEAVRLLEDGKIEELANLLGGTSGDQQTLAVLTKLAAQHNQQR 958 Query: 960 STHVDPDARYEIRWDXXXXXXXXXXXXX--DWILVGDDTAAVLEFADALTAGGHRHQIVA 1017 +T D RY+ RWD W+LVGD A DALTA G +++I+ Sbjct: 959 TTQTIADDRYQFRWDKSPMPLAGADTSTATTWLLVGDVAGAAAPLVDALTARGQQYRILG 1018 Query: 1018 LPGSDADEAQLVDTLRAASAGE--LYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRA 1075 LP SDADE QL D R+A +G+ L +VH+AA DG A+ R LLR+QH+ LGG RRLFRA Sbjct: 1019 LPTSDADEQQLADEFRSAVSGDSALRIVHVAALDGGASSARSLLRMQHQILGGTRRLFRA 1078 Query: 1076 ANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADT- 1134 A AELR+PIW++TR QR+TDTDTV PEQS LWGFGRAAALELP +WGGLADL+ A Sbjct: 1079 AAAAELRAPIWVITRGAQRITDTDTVAPEQSALWGFGRAAALELPQVWGGLADLADASAA 1138 Query: 1135 EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGL 1191 EW + I+R ++ D EDQIALR +VY PRLVRR PS TPL VR++ TYLVTGGL Sbjct: 1139 EWSQFISRASASSDAAAREDQIALRDQSVYVPRLVRRENLPSGTPLEVRDNATYLVTGGL 1198 Query: 1192 GAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVA 1251 G+IGLE+AGYLA+ GA ++VLTSRREP Q+ C+VRV+TADVADAHDVA Sbjct: 1199 GSIGLEIAGYLAARGAKNLVLTSRREPNETAQQRIDALGAQHGCEVRVVTADVADAHDVA 1258 Query: 1252 RLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTD 1311 RL+ V A+LPPLAGIVHAAGEIGTTPLS LDD+EVDRVFAGKVWGAWHLSEA DL+ Sbjct: 1259 RLLAGVQADLPPLAGIVHAAGEIGTTPLSDLDDSEVDRVFAGKVWGAWHLSEAAADLK-- 1316 Query: 1312 LDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAES 1371 LDFF+STSSIASVWGGFGQTAY AANAFLDGLAWRLRE+G+ SVNFGPW AGMADAES Sbjct: 1317 LDFFISTSSIASVWGGFGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWTAGMADAES 1376 Query: 1372 RARLEQRGVRTLSPAEALAGMADVVA-----GPVQGVVAKIDWSRFLPLYQQAGRRAFLS 1426 RARLEQRG++TLSP++ALAG+ADVVA G QGVVA+IDW+RFLPLYQQAGRRAFL+ Sbjct: 1377 RARLEQRGIKTLSPSDALAGLADVVAASQSNGGAQGVVARIDWTRFLPLYQQAGRRAFLA 1436 Query: 1427 ELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEI 1486 ELE E+ LVE+L APVQQRK L+T+YLR+AVAEVTRVD EI Sbjct: 1437 ELEREVPSHLAASQGVPQSGTTQ-LVERLAGAPVQQRKKLLTDYLRDAVAEVTRVDVSEI 1495 Query: 1487 RDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQT 1546 R++AGFFDLGMDSLMAVELR+R+EQGVGK+IPVTLVMDHPR+SD ADYLL EVLGL EQ Sbjct: 1496 REDAGFFDLGMDSLMAVELRQRMEQGVGKEIPVTLVMDHPRISDVADYLLGEVLGLSEQA 1555 Query: 1547 NV--RQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEF 1604 ++ S VT RTD+PIA+V+VSCRFPGAPDPE+FWE+L+GGVDAIREVPEDR+DIDEF Sbjct: 1556 KPAPQRVSAVTDRTDEPIAIVSVSCRFPGAPDPEAFWEVLSGGVDAIREVPEDRFDIDEF 1615 Query: 1605 YDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGY 1664 YDPDP+T GKTYTR PEFFGISPREAVWIEPQQRLMLETVWEGLERAGY Sbjct: 1616 YDPDPETAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGY 1675 Query: 1665 APSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPA 1724 +P+ LRGSRTG+F GV ANEYAHLLS+ESIDKIEP+FITGNALNAISGRVAFALGFEGPA Sbjct: 1676 SPAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPA 1735 Query: 1725 VAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKT 1784 VAVDTACSSALVAVHQA QAL SGDCDLA+AGGVNVLLSPVTV+AASRARMLSPVGRCKT Sbjct: 1736 VAVDTACSSALVAVHQAVQALHSGDCDLAVAGGVNVLLSPVTVIAASRARMLSPVGRCKT 1795 Query: 1785 FDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQR 1844 FDASADGYVRSEGCG+LVLKRLSDA RDGDRV AVIP S+VNQDGASSGLTVPNGGAQQR Sbjct: 1796 FDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQR 1855 Query: 1845 LIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNI 1904 LI LARAGL+G DVDYLEAHGTGTPLGDPIEVQ PLLMGSVK+NI Sbjct: 1856 LIGTVLARAGLAGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSREADRPLLMGSVKSNI 1915 Query: 1905 GHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVR 1964 GHTESASGAAGLIKVVLSLQ+GVLPQSLHFE PSPHIPW++LPVRV+D+ +PW+ NGR R Sbjct: 1916 GHTESASGAAGLIKVVLSLQNGVLPQSLHFEKPSPHIPWESLPVRVVDKAIPWEPNGRPR 1975 Query: 1965 RAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEAL 2024 RAGVSSFGFTGTNAHVL+EEAP + D VL LSARSPEAL Sbjct: 1976 RAGVSSFGFTGTNAHVLIEEAPRRAVATDEGGPDETAATPEAQGDKVNVLPLSARSPEAL 2035 Query: 2025 VELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTP 2084 +A+RY+ WLSA P +DI DVC TAG GRSHFE+RAALVVDSV Sbjct: 2036 AAVAQRYESWLSAHPEVDIEDVCLTAGSGRSHFEHRAALVVDSVESAREGLAELVQNRLR 2095 Query: 2085 AGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLD 2144 GV+RGEH + PTTAWLFTGQGSQYPGMARELFD +PVFA+ V +CAEAV D++ RPLL+ Sbjct: 2096 PGVIRGEHTNHPTTAWLFTGQGSQYPGMARELFDAEPVFAEIVTRCAEAVKDIVERPLLE 2155 Query: 2145 VLFATDRETAD----LLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAAC 2200 V+FATDRET +L+HTSFAQPA+FAVEMGLARLWQSW IEPDVVLGHSVGQYAAAC Sbjct: 2156 VMFATDRETGGEAGKVLRHTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAAC 2215 Query: 2201 VAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNT 2260 VAGVFSL+DGARL+AERGR+FGSLP GGRMVAVF+DA+HVEQ+A +FPRVSVGAYNGPNT Sbjct: 2216 VAGVFSLEDGARLIAERGRLFGSLPAGGRMVAVFSDAKHVEQIASDFPRVSVGAYNGPNT 2275 Query: 2261 VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPL 2320 VLSGPGED+E+ V RFE+EGIRCTWL TSHAFHSELLDPVLD PTLPL Sbjct: 2276 VLSGPGEDVEQAVARFEEEGIRCTWLETSHAFHSELLDPVLDEFESYAAQVQFATPTLPL 2335 Query: 2321 VCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ 2380 VCNRTGAVLT QTP+DAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ Sbjct: 2336 VCNRTGAVLTAQTPIDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ 2395 Query: 2381 VWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQ 2440 VWPEH+AAPRA+ SLRKGV DRRQIA+ALA+AYVGGHRP+FAA+ R PR +ELPTYPFQ Sbjct: 2396 VWPEHLAAPRAIVSLRKGVGDRRQIAEALAAAYVGGHRPNFAALQRHPRNTLELPTYPFQ 2455 Query: 2441 RRRFWPKASSIAVDGGTAAS-GILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVV 2499 RRRFWPK+S A++GG S GILG G+DLASGD++Y SRLSV+SQPWL+DHVIYGTVVV Sbjct: 2456 RRRFWPKSSGAAIEGGGGLSAGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVV 2515 Query: 2500 PGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPY 2559 PGATYAAMALAAVGTPAR KDVFFYEPIILPEK+SREVQLTLHP + GS FQ+HSRPY Sbjct: 2516 PGATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPY 2575 Query: 2560 GERGADWSLNAEGTVDTA---GSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLEL 2616 GER DWSLNAEGTV +D A +++PVD IER+ERMRP +LFETFADLEL Sbjct: 2576 GERDVDWSLNAEGTVVPGIDDSADDAAGQTSEAEPVDAAIERMERMRPHELFETFADLEL 2635 Query: 2617 AWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXX 2676 +WGPTWSGSLKSLWLG GEA+GD+LVG ELAEQLG+EPMHPVLMDLCTGV Sbjct: 2636 SWGPTWSGSLKSLWLGQGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLA 2695 Query: 2677 XEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGI 2736 EQG+NDLFLPLRYGQVTL EKMPRRFYCRARWH SALDSETQVF+LE++D GR LGGI Sbjct: 2696 AEQGINDLFLPLRYGQVTLKEKMPRRFYCRARWHESALDSETQVFDLEYLDRDGRHLGGI 2755 Query: 2737 REFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADD---AVGTWLIAGFDELAAK 2793 REFTVKRAPREALLRGLGGDATRLLYTLGWHEVP PPS D A GTWLIAGFDELAA+ Sbjct: 2756 REFTVKRAPREALLRGLGGDATRLLYTLGWHEVPVPPSEDGTAAASGTWLIAGFDELAAR 2815 Query: 2794 VPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXIT 2853 VPGC+P DR ++ ++LG+VL++A RG FSGVVWR A PG + I Sbjct: 2816 VPGCIPFDRTSNPELLGQVLAEAKERGVPFSGVVWRAAAPGAQESSTDEIARLETE--IA 2873 Query: 2854 NLLSAVHAAQGPS---VKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPAL 2910 NLLSAVH Q + VKLP GLWIVTE VA ESGEPVDPVQA+LWGFGRTTINEEPAL Sbjct: 2874 NLLSAVHTVQNGAQNGVKLPDGLWIVTERAVATESGEPVDPVQASLWGFGRTTINEEPAL 2933 Query: 2911 HCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDF 2970 +LVD DGS EAV P ++EPEIAVRQGKLLASRLLPW+RSG+LT+PRG D+ Sbjct: 2934 RAKLVDGDGSPEAVQALANLLATP-VEEPEIAVRQGKLLASRLLPWSRSGNLTVPRGSDY 2992 Query: 2971 VLAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDF 3030 L PTERGAIDNLR+TE +V PDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDF Sbjct: 2993 ALLPTERGAIDNLRITEKEVEAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDF 3052 Query: 3031 AGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALT 3090 AG VTQLG GV+ + +GQRVYGSMQGAFASRFN PAQFLAPIPDG+ AVEA TIPAAALT Sbjct: 3053 AGVVTQLGEGVTEVAVGQRVYGSMQGAFASRFNAPAQFLAPIPDGVSAVEATTIPAAALT 3112 Query: 3091 VRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGVKYV 3150 VRLAFDWAQLKPGD+VLIHAASGGVGLAAIQMAQQ GAEV+ATASTFKR+T+R+LGVKYV Sbjct: 3113 VRLAFDWAQLKPGDRVLIHAASGGVGLAAIQMAQQCGAEVYATASTFKRATVRKLGVKYV 3172 Query: 3151 YDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQ 3210 YDSRTTDFADQILADT+G GVDVVLNSLTS GFVEAT++ATA+ GRFAEIAKRDIW+ EQ Sbjct: 3173 YDSRTTDFADQILADTDGHGVDVVLNSLTSEGFVEATVRATAKNGRFAEIAKRDIWTSEQ 3232 Query: 3211 MAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFR 3270 MAEARPDIAYEIVALDTVMF EP+RIR LLTEVSDG+A+GEWTPLPAEIYP+TEAR+AFR Sbjct: 3233 MAEARPDIAYEIVALDTVMFQEPERIRGLLTEVSDGLAKGEWTPLPAEIYPLTEARTAFR 3292 Query: 3271 RMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDP 3330 RMQQARHIGKI DR+YLITGGLGAIGLHTA+YLAQLGAGDIVLTSRR P Sbjct: 3293 RMQQARHIGKIVCQMPNPLAPQPDRTYLITGGLGAIGLHTASYLAQLGAGDIVLTSRRAP 3352 Query: 3331 DESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDAL 3390 D AQR I+EI+ER K RIH + ADVG+E++V LL RIRAELPPL GIAHLAGVLDDAL Sbjct: 3353 DVDAQRLIEEISERSKARIHVFTADVGEESEVVKLLERIRAELPPLGGIAHLAGVLDDAL 3412 Query: 3391 LSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAML 3450 L Q+ ERFRTTLAPKA+GA + PGQ+NYATANA L Sbjct: 3413 LGQQSVERFRTTLAPKAFGADYLDRLTKDEDLDFFIVSSSVSSLFGSPGQSNYATANAWL 3472 Query: 3451 DGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALAEVIAN 3510 DGL+A+RR+QGL ATG+NFGPWGQGGMASSEAATANI+AQGLIPLDPSAAL ALAEVIAN Sbjct: 3473 DGLIARRRSQGLPATGVNFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVIAN 3532 Query: 3511 GSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFV 3570 G GQATV+KANWQRAAKVLGS+RPPILDLVLPSA GE TGDSELLKQLMEIP+PQRAGFV Sbjct: 3533 GVGQATVIKANWQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFV 3592 Query: 3571 TEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYP 3630 TEFLQREVQNFLRLA PPAA+SRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYP Sbjct: 3593 TEFLQREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYP 3652 Query: 3631 TIGGLAEYLVGQLPDAEA 3648 TIGGL EYLV QLPDAE+ Sbjct: 3653 TIGGLGEYLVAQLPDAES 3670 Score = 218 bits (554), Expect = 2e-53 Identities = 141/389 (36%), Positives = 200/389 (51%), Gaps = 18/389 (4%) Query: 1176 PLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYAC 1235 PL + DRTYL+TGGLGAIGL A YLA GAG +VLTSRR P E+ Sbjct: 3310 PLAPQPDRTYLITGGLGAIGLHTASYLAQLGAGDIVLTSRRAPDVDAQRLIEEISERSKA 3369 Query: 1236 DVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKV 1295 + V TADV + +V +L+ + AELPPL GI H AG + L A K Sbjct: 3370 RIHVFTADVGEESEVVKLLERIRAELPPLGGIAHLAGVLDDALLGQQSVERFRTTLAPKA 3429 Query: 1296 WGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAV 1355 +GA +L D DLDFF+ +SS++S++G GQ+ Y ANA+LDGL R R +G+ A Sbjct: 3430 FGADYLDRLTKD--EDLDFFIVSSSVSSLFGSPGQSNYATANAWLDGLIARRRSQGLPAT 3487 Query: 1356 SVNFGPWA-AGMADAESR-ARLEQRGVRTLSPAEALAGMADVVAGPV-QGVVAKIDWSRF 1412 VNFGPW GMA +E+ A + +G+ L P+ ALA +A+V+A V Q V K +W R Sbjct: 3488 GVNFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVIANGVGQATVIKANWQRA 3547 Query: 1413 LPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR 1472 + + L S + L++QL + PV QR +T +L+ Sbjct: 3548 AKVLGSSRPPILDLVLPSAVGEVTGDSE----------LLKQLMEIPVPQRAGFVTEFLQ 3597 Query: 1473 NAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPV--TLVMDHPRLSD 1530 V R+ A + F DLG DSLMA+ELR R+ G + T V D+P + Sbjct: 3598 REVQNFLRL-AQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGG 3656 Query: 1531 AADYLLVEVLGLGEQTNVRQASTVTARTD 1559 +YL+ ++ ++ Q + A+++ Sbjct: 3657 LGEYLVAQLPDAESESQEEQPAVEAAQSE 3685 >tr|B1MJ75|B1MJ75_MYCA9 Tax_Id=561007 SubName: Full=Probable polyketide synthase;[Mycobacterium abscessus] Length = 3697 Score = 5479 bits (14212), Expect = 0.0 Identities = 2800/3691 (75%), Positives = 3084/3691 (83%), Gaps = 69/3691 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M SAE+PIE TP FAIIGYAARFPGAA AEE+W +LR+GR+AIS+VP DRWD EEFFDP+ Sbjct: 1 MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADRWDAEEFFDPE 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFV+DVTGFDAPFFGMS REVRLMDPQHR+L+ETAWRAVEHSGIAPT Sbjct: 61 PGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTD 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LA +N+GVFVGLATHDYLGMASDELT+PEIEAYMAIGTSNAAAAGRISYRLGLQGP+VAV Sbjct: 121 LAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQAL+L ECDLALAGGANVLLTPATMITFS+AHMLAPDG+CKTFDA Sbjct: 181 DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEG GV+V+KRLEDA+RDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA Sbjct: 241 AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DALKRAG+ P++VGYLEAHGTGTSLGDPIEAQAAG G GR +PLLIGSAKTNIGHL Sbjct: 301 DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRETNDPLLIGSAKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LENE LP+H NF+ PSPHIPW+RLP+EVVRE PW RNG+PRIAG Sbjct: 361 EAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRNGRPRIAG 420 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVE-DPRRYSVLPLSARTPEALVRLAGEYRDW 479 VSSFGFAGTNAHVILEEAP V A P R++S+LPLSARTP AL +LA +YR W Sbjct: 421 VSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALAQLADKYRAW 480 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 L AHP+A LAD+ TAG RAHLE RAALVVN+RE+A+ELL A+ADDRPAPGL RGESH+ Sbjct: 481 LNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLSAVADDRPAPGLGRGESHD 540 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 PKTAWLFTGQGSQYPGMARELF+TEPVFA+T+ +CA AVAD+LEKPLLDVIFD D Sbjct: 541 TPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD--GP 598 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 + E LR T+YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQYSAACVA VF +EDGA Sbjct: 599 EAEETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGA 658 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLES 719 RLIAERGRLF SLPAGGRMAAVFT ERAERLTDE+PSLSVAAYNGANTVLSGPA+DLE Sbjct: 659 RLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEFPSLSVAAYNGANTVLSGPAQDLEK 718 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 A+A LVADGVRCD+L+TSHAFHSALLDPILD+FE++A + Y+ PQRILIDNRTG+ALGR Sbjct: 719 AIAALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGR 778 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 S +LDGAYWRRHARQPVEFAKSVRTLADMNC+VLLEIGP+PVLTA AL AWPDPAT P+ Sbjct: 779 SVKLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRA 838 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 +ASLR TADHRQITEA A AY GHLPDF AF+ ARKLDLPTYPFE RQ+WFSD R Sbjct: 839 IASLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRD 898 Query: 900 ID-RDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQ 958 D RD + P RT+AVRLLEDG+IEELA L+ G D+QTL VL KLAA+HN Q Sbjct: 899 GDNRDAGNRQQNNGGP-RTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLTKLAAQHNLQ 957 Query: 959 RSTHVDPDARYEIRWDXXXXXXXXXXXXXD--WILVGDDTAAVLEFADALTAGGHRHQIV 1016 R+T D RY+ RW+ W+LV D A D LTA G +H+++ Sbjct: 958 RTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAGAAQPLLDVLTARGQQHRVL 1017 Query: 1017 ALPGSDADEAQLVDTLRAASAGE--LYVVHIAA--GDGAAAPMRDLLRVQHRTLGGLRRL 1072 ALP SDADEA+LV+ LR+A+ + L +VH+AA G G+++ + LLR+QH+ LGG RRL Sbjct: 1018 ALPVSDADEAELVEALRSAADEDSALRIVHVAALAGQGSSSA-QSLLRIQHQVLGGTRRL 1076 Query: 1073 FRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGA 1132 FRAA AELR+PIW+VTR Q V + DTV PEQS LWGFGRAAALELP +WGGLADLS A Sbjct: 1077 FRAAAAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDA 1136 Query: 1133 DT-EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVT 1188 T EW + I R++ + EDQ+ALRG AV+ PRLVRR PS PL VR D TYLVT Sbjct: 1137 GTDEWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVT 1196 Query: 1189 GGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAH 1248 GGLG+IGLE+AGYLA GA H+VLTSRREP Q C+VR +TADVAD H Sbjct: 1197 GGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRIDALAAQ-GCEVRAVTADVADGH 1255 Query: 1249 DVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDL 1308 DVARL+ + AELPPLAGIVHAAGEIGTTPLS L+DAEVDRVFAGKVWGAWHLSEA L Sbjct: 1256 DVARLLAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGL 1315 Query: 1309 RTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMAD 1368 + LDFF++TSSIA+VWGG+GQTAY AANAFLDGLAWRLRE+G+ SVNFGPW+AGMAD Sbjct: 1316 K--LDFFINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMAD 1373 Query: 1369 AESRARLEQRGVRTLSPAEALAGMADVVAGP----VQGVVAKIDWSRFLPLYQQAGRRAF 1424 AESRARLEQRG++TLSP +ALAG+ADVVA VQGV+A+IDW+RFLPLYQQAG+R F Sbjct: 1374 AESRARLEQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLYQQAGKRGF 1433 Query: 1425 LSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDAD 1484 L+EL+ E+ LVE+L APVQQRK L+T+YLR+AVAEVTRVD Sbjct: 1434 LAELDREVPSHLAGVAGAQSGSTQ--LVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVS 1491 Query: 1485 EIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGE 1544 EIR++AGFFDLGMDSLMAVELRRR+EQGVGK+IPVTLVMDHPR+SD ADYLL +VLGL E Sbjct: 1492 EIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLAE 1551 Query: 1545 QTN--VRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDID 1602 Q + AS VT RTD+PIA+VAVSCRFPGAPDPE+FW++L+GGVDAIREVPEDR+DID Sbjct: 1552 QAKPAAQLASAVTGRTDEPIAIVAVSCRFPGAPDPEAFWDVLSGGVDAIREVPEDRFDID 1611 Query: 1603 EFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERA 1662 EFYDPDP+ GKTYTR PEFFGISPREAVWIEPQQRLMLETVWEGLERA Sbjct: 1612 EFYDPDPEVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERA 1671 Query: 1663 GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEG 1722 GY+P+ LRGSRTG+F GV ANEYAHLLS+ESIDKIEP+FITGNALNAISGRVAFALGFEG Sbjct: 1672 GYSPAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEG 1731 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PAVAVDTACSSALVAVHQA QAL SGDCDLALAGGVNVLLSPVTV+AASRARMLSPVGRC Sbjct: 1732 PAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRC 1791 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 KTFDASADGYVRSEGCG+LVLKRLSDA RDGDRV AVIP S+VNQDGASSGLTVPNGGAQ Sbjct: 1792 KTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQ 1851 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QRLI + LARAGL G DVDYLEAHGTGTPLGDPIEVQ PLLMGSVK+ Sbjct: 1852 QRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKS 1911 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGHTESASGAAGLIKVVLSLQ+GVLPQSLHF+NPSPHIPW++LPVRV+D+ +PWQ NGR Sbjct: 1912 NIGHTESASGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGR 1971 Query: 1963 VRRAGVSSFGFTGTNAHVLVEEAP-PQLHXXXXXXXXXXXXXXXGTDDS--PQ-----VL 2014 RRAGVSSFGFTGTNAHVL+EEAP PQ DD+ PQ VL Sbjct: 1972 PRRAGVSSFGFTGTNAHVLIEEAPQPQA--------------TPDEDDASTPQSAPVSVL 2017 Query: 2015 ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXX 2074 LSARSPEAL +A+RY+ WL+A P +D+ DVC TAG GRSHFE+RAALVVDS+ Sbjct: 2018 PLSARSPEALAAVAQRYESWLAAHPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREG 2077 Query: 2075 XXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAV 2134 GVVRGEH + PTTAWLFTGQGSQYPGMARELFD +PVFA+TV +CAEAV Sbjct: 2078 LLELAQNRLRPGVVRGEHTNHPTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAV 2137 Query: 2135 ADMLPRPLLDVLFATDRETA----DLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLG 2190 D++ RPLL+V+FATDRET + L+HTSFAQPALFAVEMGLARLWQSW IEPDVVLG Sbjct: 2138 KDIVTRPLLEVMFATDRETGGKAGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLG 2197 Query: 2191 HSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRV 2250 HSVGQYAAACVAGVFS++DGARL+AERGR+FG LP GGRMVAVF+DA+HVEQ+AGEFPRV Sbjct: 2198 HSVGQYAAACVAGVFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRV 2257 Query: 2251 SVGAYNGPNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXX 2310 SVGAYNGPNTVLSGPGEDLE+ V RF++EGIRCTWL TSHAFHSELLDP+LD Sbjct: 2258 SVGAYNGPNTVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQ 2317 Query: 2311 XXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGP 2370 PTLPLVCNRTGAVLT QTP+D QYWRRHSRQPVQFAESVRTVAALGCSVLMEIGP Sbjct: 2318 VQFAAPTLPLVCNRTGAVLTAQTPIDGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGP 2377 Query: 2371 QPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRR 2430 QPVLTGAAVQVWPEH+A PRA+ SLRKGV DRRQIADALASAYV GHRP+FAA+ R PRR Sbjct: 2378 QPVLTGAAVQVWPEHLAPPRAIVSLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRR 2437 Query: 2431 PVELPTYPFQRRRFWPKASSIAVDGGTAA-SGILGSGKDLASGDTIYTSRLSVKSQPWLA 2489 VELPTYPFQRRRFWPK+S A++GG SGILG G+DLASGD++Y SRLSV+SQPWL+ Sbjct: 2438 TVELPTYPFQRRRFWPKSSGTAIEGGGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLS 2497 Query: 2490 DHVIYGTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSV 2549 DHVIYGTVVVPGATYAAMALAAVGTPAR KDVFFYEPIILPEK+SREVQLTLHP + GS Sbjct: 2498 DHVIYGTVVVPGATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSG 2557 Query: 2550 LSFQIHSRPYGERGADWSLNAEGTVDTAGSD---PDAAADEQSDPVDEVIERLERMRPQD 2606 FQ+HSRPYGER DWSLNAEGTV T D P A E ++PVD IER+ERMRP + Sbjct: 2558 SKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPME 2617 Query: 2607 LFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGV 2666 LFE FADLELAWGPTWSGSLKSLWLG+GEA+GD+LVG ELAEQLG+EPMHPVLMDLCTGV Sbjct: 2618 LFEIFADLELAWGPTWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGV 2677 Query: 2667 XXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFV 2726 EQGVNDLFLPLRYGQVTL EKMPRRFYCRARWH S LDSETQVF+L+++ Sbjct: 2678 AFPAFPALLAAEQGVNDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYL 2737 Query: 2727 DLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADD------AVG 2780 D GR LGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEV PP A + ++G Sbjct: 2738 DRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVAVPPVAGEGEESAASIG 2797 Query: 2781 TWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXX 2840 TWLIAGFDELAAKVPGC+P++R TD ++LGEVL A RG FSGVVWR A PG Sbjct: 2798 TWLIAGFDELAAKVPGCIPLNRETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATESTT 2857 Query: 2841 XXXXXXXXXXXITNLLSAVHAAQGPS---VKLPGGLWIVTEHGVACESGEPVDPVQAALW 2897 I +LLSAVH Q + VKLPGGLWIVTE VA ESGEPVDPVQAALW Sbjct: 2858 ESAARLEGE--IAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALW 2915 Query: 2898 GFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWA 2957 GFGRTTINEEPAL +LVD DGS EAV P + EPEIAVRQGKLLASRLLPW+ Sbjct: 2916 GFGRTTINEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLPWS 2974 Query: 2958 RSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLG 3017 R+GHLT+PRG D+VLAPTERGAIDNLR+TE +VP PDEGYVQVRVEAAGLNFRDVLNVLG Sbjct: 2975 RTGHLTVPRGSDYVLAPTERGAIDNLRITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLG 3034 Query: 3018 LYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIG 3077 LYPGDPGPIGGDFAG VTQLG GV+G+E+GQRVYGSMQGAF SRFNVPAQFLAPIPDGI Sbjct: 3035 LYPGDPGPIGGDFAGIVTQLGEGVTGVEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGIS 3094 Query: 3078 AVEAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTF 3137 VEAATIPAAALTVRL+FDWAQLKPGDKVLIHAASGGVGLAAIQMAQQ GAEVFATASTF Sbjct: 3095 GVEAATIPAAALTVRLSFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTF 3154 Query: 3138 KRSTLRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRF 3197 KR+TLR+LGVKYVYDSRTTDFADQILADT+GAGVDVVLNSLTS GF+EATL+ATA+ GRF Sbjct: 3155 KRATLRKLGVKYVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRF 3214 Query: 3198 AEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPA 3257 AEIAKRDIW+ EQMA++RPDIAYEIVALDTVMF EPDRIR LLTEVS+G+A+GEWTPLPA Sbjct: 3215 AEIAKRDIWTTEQMAQSRPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAKGEWTPLPA 3274 Query: 3258 EIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQL 3317 EIYP+TEAR+AFRRMQQARHIGKI DR+YLITGGLGAIGLHTAAYLAQL Sbjct: 3275 EIYPLTEARTAFRRMQQARHIGKIVCQMPNPLAPRPDRTYLITGGLGAIGLHTAAYLAQL 3334 Query: 3318 GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLA 3377 GAGDIVLTSRR PD AQR I EITER K RIH + ADVG E++VA LL RIRAELPPLA Sbjct: 3335 GAGDIVLTSRRAPDTDAQRVIGEITERSKTRIHVFTADVGAESEVAGLLERIRAELPPLA 3394 Query: 3378 GIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXX 3437 G+AHLAGVLDDALL Q+ ERFRTTLAPKA+GA + Sbjct: 3395 GVAHLAGVLDDALLGQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGS 3454 Query: 3438 PGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDP 3497 PGQ+NYATANA+LDGL+A+RRAQGL ATGINFGPWGQGGMASSEAATANI+AQGLIPLDP Sbjct: 3455 PGQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATANISAQGLIPLDP 3514 Query: 3498 SAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQ 3557 SAAL ALAEV+ANG+GQAT+LKANWQRAAKVLGS+RPPILDLVLPSA GE TGDSELLKQ Sbjct: 3515 SAALAALAEVVANGTGQATILKANWQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQ 3574 Query: 3558 LMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGG 3617 LMEIP+PQRAGFVTEFLQREVQNFLRLA PPAA+SRFLDLGTDSLMAIELRNRLHSQFGG Sbjct: 3575 LMEIPVPQRAGFVTEFLQREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGG 3634 Query: 3618 KFTINATAVFDYPTIGGLAEYLVGQLPDAEA 3648 KFTINATAVFDYPTIGGLAEYLVGQLPDA+A Sbjct: 3635 KFTINATAVFDYPTIGGLAEYLVGQLPDADA 3665 >tr|A4T3X4|A4T3X4_MYCGI Tax_Id=350054 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium gilvum] Length = 3679 Score = 5479 bits (14212), Expect = 0.0 Identities = 2797/3682 (75%), Positives = 3076/3682 (83%), Gaps = 46/3682 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M SA H E FAI+GYA RFPGA AE +W LL DGR+AIS+VP+DRWD+E FFDPD Sbjct: 1 MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDRWDVEAFFDPD 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 PSTPGKVVTRRAGFVDDV+GFDAPFFGMS REVRLMDPQHR+L+ETAWRA+EHSG AP+ Sbjct: 61 PSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSE 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LAN+NTGVFVGLATHDYLGMASDEL+YPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV Sbjct: 121 LANTNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQALRL ECDLALAGGANV+LTPATMITFSNAHMLAPDGRCKTFDA Sbjct: 181 DTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGV+V+KRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI Sbjct: 241 AADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DAL RAGL P DV YLEAHGTGTSLGDPIEAQAAG LG GR P+ PLLIGSAKTNIGHL Sbjct: 301 DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLIGSAKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPW---QRNGKPR 417 E LE+ETLPKHLNFE PSPHIPW+RLP+EVV+E++PW QR G+PR Sbjct: 361 EAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPR 420 Query: 418 IAGVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYR 477 IAGVSSFGFAGTNAHVILEEAP PA E V+D R +++LPLSARTP AL+ +A YR Sbjct: 421 IAGVSSFGFAGTNAHVILEEAPLAAEPAQ-ESVDDGR-FTLLPLSARTPAALMAVADRYR 478 Query: 478 DWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGES 537 DWL A+P A LAD+ TAGTAR+HLE RAALVVN+RE+A++LLGALADDRPAPGLVRGES Sbjct: 479 DWLVANPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGES 538 Query: 538 HEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADE- 596 H+ PKTAWLFTGQGSQYPGM+RELFDTEP+FAET+R+CA AV +LEKPLLDVIFD D Sbjct: 539 HDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGV 598 Query: 597 LDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVE 656 LD D+ LRHT+YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQY+AACVAGV + Sbjct: 599 LDTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLR 658 Query: 657 DGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKD 716 DGARL+AERGRLFGSLP+GGRMAAVF A ER E LTDEYP+LSVAAYNGANTVLSGPA D Sbjct: 659 DGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPALSVAAYNGANTVLSGPATD 718 Query: 717 LESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSA 776 LE AVA LVADGVRCDWL+TSHAFHSALLDPILDDFES+A+ + + PQRILIDNRTG+A Sbjct: 719 LERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFTAPQRILIDNRTGAA 778 Query: 777 LGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATT 836 LGRS LD AYWRRHARQPVEFAKSV TLADMNC++L+EIGPRPVLTA AL+AWPDPAT+ Sbjct: 779 LGRSVTLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATS 838 Query: 837 PQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSD 896 P+V+ASLR TTAD RQITEAVA AY GHLP F AFR+ AR LDLPTYPFEHRQ+WFSD Sbjct: 839 PRVIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSD 898 Query: 897 NRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHN 956 +R + +A RT+ VRLLEDG+IEELAAL+ G D T VLN+LAA+HN Sbjct: 899 SR------EPVAAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLNRLAAQHN 952 Query: 957 QQRSTHVDPDARYEIRWDXXXXXXXXXXXXXD--WILVGDDTAAVLEFADALTAGGHRHQ 1014 QQRST D RY+IRW+ W+LVGDDT A D L A GHR++ Sbjct: 953 QQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDATRPLVDVLAARGHRYR 1012 Query: 1015 IVALPGSDADEAQLVDTLR--AASAGELYVVHIAAGDGAAAP--MRDLLRVQHRTLGGLR 1070 I+ LP S A+E +L DTLR AA A +L +VH+AA D A + M+ LLR+QHR LGG R Sbjct: 1013 ILGLPKSGAEEHELADTLRDAAADATDLRIVHVAALDAAESDTSMKSLLRMQHRVLGGTR 1072 Query: 1071 RLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLS 1130 RLF AA A+LRSP+WLVTR Q VTDTD V P+Q+CLWGFGRAA+LE P IWGGLADL Sbjct: 1073 RLFGAAVAAQLRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLG 1132 Query: 1131 GADT-EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYL 1186 G + EW RL+ RI + D EDQ+A+RG Y PRLV R PS PL +R D TYL Sbjct: 1133 GGTSDEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADATYL 1192 Query: 1187 VTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVAD 1246 VTGGLG++GLE+AGYLA++GAGH+VLTSRR P E++ C+VRV+TADVAD Sbjct: 1193 VTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERHGCEVRVVTADVAD 1252 Query: 1247 AHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALT 1306 AH VARL+ TV AE+PPLAGIVHAAGEIGTTPL+ LDDAEVDRVFAGKVWGAWHLSEA + Sbjct: 1253 AHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATS 1312 Query: 1307 DLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGM 1366 DL+ LDFF+STSSIASVWGGFGQ AYGAANAFLDGLAWRLRE+GV VSVNFGPW+AGM Sbjct: 1313 DLQ--LDFFISTSSIASVWGGFGQAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGM 1370 Query: 1367 ADAESRARLEQRGVRTLSPAEALAGMAD-VVAGPVQGVVAKIDWSRFLPLYQQAGRRAFL 1425 ADA+SRARLEQRG++TLSPA+ALAG++D V++ VVA++DWSRFLPLYQQAGRR FL Sbjct: 1371 ADAQSRARLEQRGIKTLSPADALAGLSDAVISAAPHPVVARVDWSRFLPLYQQAGRRGFL 1430 Query: 1426 SELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADE 1485 +ELE EL LVE+LT AP+QQRK L+T+YLR+AVAEVTRVDA E Sbjct: 1431 AELERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAE 1490 Query: 1486 IRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQ 1545 IR++AGFFDLGMDSLMAVELRRRIE GVGK+IPVTLVMDHPRLSDAADYLL +VLGL E Sbjct: 1491 IREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGDVLGLTEA 1550 Query: 1546 TNVRQASTVTART-DDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEF 1604 +A+TV + D+PIA+VAVSCRFPGAP+PE+FW+LL+GGVDAIREVPEDR+DIDEF Sbjct: 1551 ATAPKAATVVSTAADEPIAIVAVSCRFPGAPNPEAFWDLLSGGVDAIREVPEDRFDIDEF 1610 Query: 1605 YDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGY 1664 YDPDPD GKTYTR PEFFG+SPREAVWIEPQQRLMLETVWEGLERAGY Sbjct: 1611 YDPDPDAAGKTYTRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGY 1670 Query: 1665 APSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPA 1724 APS LRGSRTGVF GVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALG EGPA Sbjct: 1671 APSALRGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPA 1730 Query: 1725 VAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKT 1784 VAVDTACSS+LVAVHQA QAL+SGDCD+ALAGGVNVLLSPVTVVAASRARMLSPVGRCKT Sbjct: 1731 VAVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRCKT 1790 Query: 1785 FDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQR 1844 FDASADGYVRSEGCG+LVLKRLSDAVRDGDRVCAVI S+VNQDGASSGLTVPNGGAQQR Sbjct: 1791 FDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASSGLTVPNGGAQQR 1850 Query: 1845 LIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNI 1904 LI LARAG++G +VDYLEAHGTGTPLGDPIEVQ PLLMGSVKTNI Sbjct: 1851 LIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAAAAAYAGARDADRPLLMGSVKTNI 1910 Query: 1905 GHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVR 1964 GHTESASGAAGLIKVVLSLQH LPQSLHF+ PSPHIPWD+LPVRV+D +PWQ NGR R Sbjct: 1911 GHTESASGAAGLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQPNGRPR 1970 Query: 1965 RAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSP----QVLALSARS 2020 RAGVSSFGFTGTNAHVL+EEAP L D +VL LSARS Sbjct: 1971 RAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARS 2030 Query: 2021 PEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXX 2080 PEALV LA+RY+ WL+A P D+ADVC TAG GRSHFE+RAALVVDSV Sbjct: 2031 PEALVALAQRYETWLTAHPEADLADVCRTAGTGRSHFEHRAALVVDSVESARIALTDLAQ 2090 Query: 2081 XXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPR 2140 GVVRGEH++ PTTAW+FTGQGSQYPGMARELFDT+PVFA TV +CA+AVAD+LPR Sbjct: 2091 NRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMARELFDTEPVFADTVTRCADAVADLLPR 2150 Query: 2141 PLLDVLFATDRETA----DLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQY 2196 PLLDV+FA RE + L+HTSFAQPALFAVEMGLARLWQSW I PDVVLGHSVGQY Sbjct: 2151 PLLDVMFAGGREAGVPPTETLRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQY 2210 Query: 2197 AAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYN 2256 AAACVAGVFSL+DGARLMAERGR+FGSLPEGGRMVAVFADA+ VEQVA +FPRVSVGAYN Sbjct: 2211 AAACVAGVFSLEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPRVSVGAYN 2270 Query: 2257 GPNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXP 2316 GPNTVLSGPGEDLE+IV F ++GIRCTWL TSHAFHSELLDPVLD P Sbjct: 2271 GPNTVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAAQLQFAAP 2330 Query: 2317 TLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG 2376 TLPLVCNRTGAVLTGQT LDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG Sbjct: 2331 TLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG 2390 Query: 2377 AAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPT 2436 AAVQVWPEH+AAPRA+ASLRKGVADRRQIADALA+AY+GGH+PDFAA+H Q +ELPT Sbjct: 2391 AAVQVWPEHLAAPRAIASLRKGVADRRQIADALAAAYIGGHKPDFAALHEQRGVRLELPT 2450 Query: 2437 YPFQRRRFWPKASSIAVDG---GTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVI 2493 YPFQRRRFWPK++ +A+DG +A SGILGSGKDLASGD++YTSRLSVK+QPWL+DHVI Sbjct: 2451 YPFQRRRFWPKSAGMAIDGRVGASAGSGILGSGKDLASGDSVYTSRLSVKTQPWLSDHVI 2510 Query: 2494 YGTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPA-DGGSVLSF 2552 YGTVVVPGATYAAMALAAVGTPA KDVFFYEPIILPEK+SREVQLT+HP+ DG S F Sbjct: 2511 YGTVVVPGATYAAMALAAVGTPAHAKDVFFYEPIILPEKSSREVQLTVHPSVDGES--KF 2568 Query: 2553 QIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFA 2612 Q+HSRPYGERGA+W+LNAEG V + D AAA + DPVDE IERL RMRPQ+LFETFA Sbjct: 2569 QVHSRPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDEAIERLNRMRPQELFETFA 2628 Query: 2613 DLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXX 2672 DLELAWGPTWSGSLKSLWLG+GEA+GDILVGAELAEQLG+EPMHPVLMDLCTGV Sbjct: 2629 DLELAWGPTWSGSLKSLWLGEGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAFPAFP 2688 Query: 2673 XXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRA 2732 EQGVNDL+LPLRYGQV+L EKMPRRFYCRA WH + LDSETQVF+LE++D GR Sbjct: 2689 ALLAAEQGVNDLYLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRH 2748 Query: 2733 LGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAV--GTWLIAGFDEL 2790 LGG+REFTVKRAPREALLRGLGGDATRLLYTLGWHEVP P S D A GTWLI GFDEL Sbjct: 2749 LGGVREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPVPESGDGAAPQGTWLIGGFDEL 2808 Query: 2791 AAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXX 2850 A VPGC+P DR T+ + L ++L+ AH RG FSGVVWR A Sbjct: 2809 AVSVPGCIPADR-TNPESLRQLLTDAHGRGLPFSGVVWRAARSD--GDESDAEVAARLEA 2865 Query: 2851 XITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPAL 2910 I LL AVH QG VKLPGGLWIVTE VA ESGEPVDPVQAALWGFGRT INEEPAL Sbjct: 2866 EIAELLGAVHTVQGGEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPAL 2925 Query: 2911 HCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDF 2970 CRLVDCDGS +AV P + EPE+AVRQGKLLASRLLPW+RSGHLT+PRGGD+ Sbjct: 2926 RCRLVDCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLLPWSRSGHLTVPRGGDY 2984 Query: 2971 VLAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDF 3030 VLAPTERGAIDNLRLT+++VP P EGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDF Sbjct: 2985 VLAPTERGAIDNLRLTDSEVPPPAEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDF 3044 Query: 3031 AGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALT 3090 AGTVTQLG GV+GL++GQRVYGSMQGAFASRFNVP QFLAPIPDG+ AVEAATIPAAALT Sbjct: 3045 AGTVTQLGEGVTGLDVGQRVYGSMQGAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALT 3104 Query: 3091 VRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGVKYV 3150 VRL+FDWAQ+K GDKVLIHAASGGVGLAA+QMAQQ GAEV+ATASTFKR+TLR+LGVK+V Sbjct: 3105 VRLSFDWAQVKSGDKVLIHAASGGVGLAAVQMAQQCGAEVYATASTFKRATLRKLGVKHV 3164 Query: 3151 YDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQ 3210 YDSRTTDFA+QILADT+GAGVDVVLNSLTS GF+EATL+ATAQ GRFAEIAKRDIW+ EQ Sbjct: 3165 YDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTVEQ 3224 Query: 3211 MAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFR 3270 MA ARPD+AYEIVALDTVMFTEPDRIRDLLTEVS G+ G WTPLPAE+YP+TEAR+AFR Sbjct: 3225 MAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPLPAEVYPLTEARAAFR 3284 Query: 3271 RMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDP 3330 RMQQARHIGKI DRSYLITGGLGAIGLHTA YLAQLGAGDIVLTSRR P Sbjct: 3285 RMQQARHIGKIVVQIPNPLQPQPDRSYLITGGLGAIGLHTAGYLAQLGAGDIVLTSRRAP 3344 Query: 3331 DESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDAL 3390 D +AQ+AI +I +R K R+H + ADVG EA VA LL RIRAELPPLAG+AHLAGVLDDAL Sbjct: 3345 DAAAQQAIADIADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDAL 3404 Query: 3391 LSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAML 3450 LS Q+ ERFRT LAPKA+GA H PGQ+NYATANA L Sbjct: 3405 LSQQSVERFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATANAFL 3464 Query: 3451 DGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALAEVIAN 3510 DGLVA+RRAQGL ATG+NFGPW +GGMASSEAA ANI+AQGLIPL+PSAAL A+AEV+AN Sbjct: 3465 DGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANISAQGLIPLEPSAALTAMAEVVAN 3524 Query: 3511 GSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFV 3570 G+ QATVLKANWQRAAKVLGS+RPPILDLVLPSA GE TGDSELLKQL EIP+PQRAGFV Sbjct: 3525 GTAQATVLKANWQRAAKVLGSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFV 3584 Query: 3571 TEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYP 3630 TEFLQ+EVQNFLRLA PPAA+SRFLDLGTDSLMAIELRNRLHSQFGG FTINATAVFDYP Sbjct: 3585 TEFLQKEVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYP 3644 Query: 3631 TIGGLAEYLVGQLPDAEAPETA 3652 TIGGLAEYLV QLPDAE P+ A Sbjct: 3645 TIGGLAEYLVAQLPDAETPQAA 3666 >tr|A5A9V0|A5A9V0_MYCAB Tax_Id=36809 (pks)SubName: Full=Pks protein;[Mycobacterium abscessus] Length = 3697 Score = 5479 bits (14212), Expect = 0.0 Identities = 2800/3691 (75%), Positives = 3084/3691 (83%), Gaps = 69/3691 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M SAE+PIE TP FAIIGYAARFPGAA AEE+W +LR+GR+AIS+VP DRWD EEFFDP+ Sbjct: 1 MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADRWDAEEFFDPE 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFV+DVTGFDAPFFGMS REVRLMDPQHR+L+ETAWRAVEHSGIAPT Sbjct: 61 PGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTD 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LA +N+GVFVGLATHDYLGMASDELT+PEIEAYMAIGTSNAAAAGRISYRLGLQGP+VAV Sbjct: 121 LAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQAL+L ECDLALAGGANVLLTPATMITFS+AHMLAPDG+CKTFDA Sbjct: 181 DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEG GV+V+KRLEDA+RDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA Sbjct: 241 AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 DALKRAG+ P++VGYLEAHGTGTSLGDPIEAQAAG G GR +PLLIGSAKTNIGHL Sbjct: 301 DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRETNDPLLIGSAKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LENE LP+H NF+ PSPHIPW+RLP+EVVRE PW RNG+PRIAG Sbjct: 361 EAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRNGRPRIAG 420 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVE-DPRRYSVLPLSARTPEALVRLAGEYRDW 479 VSSFGFAGTNAHVILEEAP V A P R++S+LPLSARTP AL +LA +YR W Sbjct: 421 VSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALAQLADKYRAW 480 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 L AHP+A LAD+ TAG RAHLE RAALVVN+RE+A+ELL A+ADDRPAPGL RGESH+ Sbjct: 481 LNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLSAVADDRPAPGLGRGESHD 540 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 PKTAWLFTGQGSQYPGMARELF+TEPVFA+T+ +CA AVAD+LEKPLLDVIFD D Sbjct: 541 TPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD--GP 598 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 + E LR T+YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQYSAACVA VF +EDGA Sbjct: 599 EAEETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGA 658 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLES 719 RLIAERGRLF SLPAGGRMAAVFT ERAERLTDE+PSLSVAAYNGANTVLSGPA+DLE Sbjct: 659 RLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEFPSLSVAAYNGANTVLSGPAQDLEK 718 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 A+A LVADGVRCD+L+TSHAFHSALLDPILD+FE++A + Y+ PQRILIDNRTG+ALGR Sbjct: 719 AIAALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGR 778 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 S +LDGAYWRRHARQPVEFAKSVRTLADMNC+VLLEIGP+PVLTA AL AWPDPAT P+ Sbjct: 779 SVKLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRA 838 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 +ASLR TADHRQITEA A AY GHLPDF AF+ ARKLDLPTYPFE RQ+WFSD R Sbjct: 839 IASLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRD 898 Query: 900 ID-RDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQ 958 D RD + P RT+AVRLLEDG+IEELA L+ G D+QTL VL KLAA+HN Q Sbjct: 899 GDNRDAGNRQQNNGGP-RTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLTKLAAQHNLQ 957 Query: 959 RSTHVDPDARYEIRWDXXXXXXXXXXXXXD--WILVGDDTAAVLEFADALTAGGHRHQIV 1016 R+T D RY+ RW+ W+LV D A D LTA G +H+++ Sbjct: 958 RTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAGAAQPLLDVLTARGQQHRVL 1017 Query: 1017 ALPGSDADEAQLVDTLRAASAGE--LYVVHIAA--GDGAAAPMRDLLRVQHRTLGGLRRL 1072 ALP SDADEA+LV+ LR+A+ + L +VH+AA G G+++ + LLR+QH+ LGG RRL Sbjct: 1018 ALPVSDADEAELVEALRSAADEDSALRIVHVAALAGQGSSSA-QSLLRIQHQVLGGTRRL 1076 Query: 1073 FRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGA 1132 FRAA AELR+PIW+VTR Q V + DTV PEQS LWGFGRAAALELP +WGGLADLS A Sbjct: 1077 FRAAAAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDA 1136 Query: 1133 DT-EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVT 1188 T EW + I R++ + EDQ+ALRG AV+ PRLVRR PS PL VR D TYLVT Sbjct: 1137 GTDEWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVT 1196 Query: 1189 GGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAH 1248 GGLG+IGLE+AGYLA GA H+VLTSRREP Q C+VR +TADVAD H Sbjct: 1197 GGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRIDALAAQ-GCEVRAVTADVADGH 1255 Query: 1249 DVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDL 1308 DVARL+ + AELPPLAGIVHAAGEIGTTPLS L+DAEVDRVFAGKVWGAWHLSEA L Sbjct: 1256 DVARLLAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGL 1315 Query: 1309 RTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMAD 1368 + LDFF++TSSIA+VWGG+GQTAY AANAFLDGLAWRLRE+G+ SVNFGPW+AGMAD Sbjct: 1316 K--LDFFINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMAD 1373 Query: 1369 AESRARLEQRGVRTLSPAEALAGMADVVAGP----VQGVVAKIDWSRFLPLYQQAGRRAF 1424 AESRARLEQRG++TLSP +ALAG+ADVVA VQGV+A+IDW+RFLPLYQQAG+R F Sbjct: 1374 AESRARLEQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLYQQAGKRGF 1433 Query: 1425 LSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDAD 1484 L+EL+ E+ LVE+L APVQQRK L+T+YLR+AVAEVTRVD Sbjct: 1434 LAELDREVPSHLAGVAGAQSGSTQ--LVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVS 1491 Query: 1485 EIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGE 1544 EIR++AGFFDLGMDSLMAVELRRR+EQGVGK+IPVTLVMDHPR+SD ADYLL +VLGL E Sbjct: 1492 EIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLAE 1551 Query: 1545 QTN--VRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDID 1602 Q + AS VT RTD+PIA+VAVSCRFPGAPDPE+FW++L+GGVDAIREVPEDR+DID Sbjct: 1552 QAKPAAQLASAVTGRTDEPIAIVAVSCRFPGAPDPEAFWDVLSGGVDAIREVPEDRFDID 1611 Query: 1603 EFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERA 1662 EFYDPDP+ GKTYTR PEFFGISPREAVWIEPQQRLMLETVWEGLERA Sbjct: 1612 EFYDPDPEVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERA 1671 Query: 1663 GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEG 1722 GY+P+ LRGSRTG+F GV ANEYAHLLS+ESIDKIEP+FITGNALNAISGRVAFALGFEG Sbjct: 1672 GYSPAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEG 1731 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PAVAVDTACSSALVAVHQA QAL SGDCDLALAGGVNVLLSPVTV+AASRARMLSPVGRC Sbjct: 1732 PAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRC 1791 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 KTFDASADGYVRSEGCG+LVLKRLSDA RDGDRV AVIP S+VNQDGASSGLTVPNGGAQ Sbjct: 1792 KTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQ 1851 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QRLI + LARAGL G DVDYLEAHGTGTPLGDPIEVQ PLLMGSVK+ Sbjct: 1852 QRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKS 1911 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGHTESASGAAGLIKVVLSLQ+GVLPQSLHF+NPSPHIPW++LPVRV+D+ +PWQ NGR Sbjct: 1912 NIGHTESASGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGR 1971 Query: 1963 VRRAGVSSFGFTGTNAHVLVEEAP-PQLHXXXXXXXXXXXXXXXGTDDS--PQ-----VL 2014 RRAGVSSFGFTGTNAHVL+EEAP PQ DD+ PQ VL Sbjct: 1972 PRRAGVSSFGFTGTNAHVLIEEAPQPQA--------------TPDEDDASTPQSAPVSVL 2017 Query: 2015 ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXX 2074 LSARSPEAL +A+RY+ WL+A P +D+ DVC TAG GRSHFE+RAALVVDS+ Sbjct: 2018 PLSARSPEALAAVAQRYESWLAAHPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREG 2077 Query: 2075 XXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAV 2134 GVVRGEH + PTTAWLFTGQGSQYPGMARELFD +PVFA+TV +CAEAV Sbjct: 2078 LLELAQNRLRPGVVRGEHTNHPTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAV 2137 Query: 2135 ADMLPRPLLDVLFATDRETA----DLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLG 2190 D++ RPLL+V+FATDRET + L+HTSFAQPALFAVEMGLARLWQSW IEPDVVLG Sbjct: 2138 KDIVTRPLLEVMFATDRETGGKAGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLG 2197 Query: 2191 HSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRV 2250 HSVGQYAAACVAGVFS++DGARL+AERGR+FG LP GGRMVAVF+DA+HVEQ+AGEFPRV Sbjct: 2198 HSVGQYAAACVAGVFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRV 2257 Query: 2251 SVGAYNGPNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXX 2310 SVGAYNGPNTVLSGPGEDLE+ V RF++EGIRCTWL TSHAFHSELLDP+LD Sbjct: 2258 SVGAYNGPNTVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQ 2317 Query: 2311 XXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGP 2370 PTLPLVCNRTGAVLT QTP+D QYWRRHSRQPVQFAESVRTVAALGCSVLMEIGP Sbjct: 2318 VQFAAPTLPLVCNRTGAVLTAQTPIDGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGP 2377 Query: 2371 QPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRR 2430 QPVLTGAAVQVWPEH+A PRA+ SLRKGV DRRQIADALASAYV GHRP+FAA+ R PRR Sbjct: 2378 QPVLTGAAVQVWPEHLAPPRAIVSLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRR 2437 Query: 2431 PVELPTYPFQRRRFWPKASSIAVDGGTAA-SGILGSGKDLASGDTIYTSRLSVKSQPWLA 2489 VELPTYPFQRRRFWPK+S A++GG SGILG G+DLASGD++Y SRLSV+SQPWL+ Sbjct: 2438 TVELPTYPFQRRRFWPKSSGTAIEGGGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLS 2497 Query: 2490 DHVIYGTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSV 2549 DHVIYGTVVVPGATYAAMALAAVGTPAR KDVFFYEPIILPEK+SREVQLTLHP + GS Sbjct: 2498 DHVIYGTVVVPGATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSG 2557 Query: 2550 LSFQIHSRPYGERGADWSLNAEGTVDTAGSD---PDAAADEQSDPVDEVIERLERMRPQD 2606 FQ+HSRPYGER DWSLNAEGTV T D P A E ++PVD IER+ERMRP + Sbjct: 2558 SKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPME 2617 Query: 2607 LFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGV 2666 LFE FADLELAWGPTWSGSLKSLWLG+GEA+GD+LVG ELAEQLG+EPMHPVLMDLCTGV Sbjct: 2618 LFEIFADLELAWGPTWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGV 2677 Query: 2667 XXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFV 2726 EQGVNDLFLPLRYGQVTL EKMPRRFYCRARWH S LDSETQVF+L+++ Sbjct: 2678 AFPAFPALLAAEQGVNDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYL 2737 Query: 2727 DLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADD------AVG 2780 D GR LGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEV PP A + ++G Sbjct: 2738 DRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVAVPPVAGEGEESAASIG 2797 Query: 2781 TWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXX 2840 TWLIAGFDELAAKVPGC+P++R TD ++LGEVL A RG FSGVVWR A PG Sbjct: 2798 TWLIAGFDELAAKVPGCIPLNRETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATESTT 2857 Query: 2841 XXXXXXXXXXXITNLLSAVHAAQGPS---VKLPGGLWIVTEHGVACESGEPVDPVQAALW 2897 I +LLSAVH Q + VKLPGGLWIVTE VA ESGEPVDPVQAALW Sbjct: 2858 ESAARLEGE--IAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALW 2915 Query: 2898 GFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWA 2957 GFGRTTINEEPAL +LVD DGS EAV P + EPEIAVRQGKLLASRLLPW+ Sbjct: 2916 GFGRTTINEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLPWS 2974 Query: 2958 RSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLG 3017 R+GHLT+PRG D+VLAPTERGAIDNLR+TE +VP PDEGYVQVRVEAAGLNFRDVLNVLG Sbjct: 2975 RTGHLTVPRGSDYVLAPTERGAIDNLRITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLG 3034 Query: 3018 LYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIG 3077 LYPGDPGPIGGDFAG VTQLG GV+G+E+GQRVYGSMQGAF SRFNVPAQFLAPIPDGI Sbjct: 3035 LYPGDPGPIGGDFAGIVTQLGEGVTGVEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGIS 3094 Query: 3078 AVEAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTF 3137 VEAATIPAAALTVRL+FDWAQLKPGDKVLIHAASGGVGLAAIQMAQQ GAEVFATASTF Sbjct: 3095 GVEAATIPAAALTVRLSFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTF 3154 Query: 3138 KRSTLRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRF 3197 KR+TLR+LGVKYVYDSRTTDFADQILADT+GAGVDVVLNSLTS GF+EATL+ATA+ GRF Sbjct: 3155 KRATLRKLGVKYVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRF 3214 Query: 3198 AEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPA 3257 AEIAKRDIW+ EQMA++RPDIAYEIVALDTVMF EPDRIR LLTEVS+G+A+GEWTPLPA Sbjct: 3215 AEIAKRDIWTTEQMAQSRPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAKGEWTPLPA 3274 Query: 3258 EIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQL 3317 EIYP+TEAR+AFRRMQQARHIGKI DR+YLITGGLGAIGLHTAAYLAQL Sbjct: 3275 EIYPLTEARTAFRRMQQARHIGKIVCQMPNPLAPRPDRTYLITGGLGAIGLHTAAYLAQL 3334 Query: 3318 GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLA 3377 GAGDIVLTSRR PD AQR I EITER K RIH + ADVG E++VA LL RIRAELPPLA Sbjct: 3335 GAGDIVLTSRRAPDTDAQRVIGEITERSKTRIHVFTADVGAESEVAGLLERIRAELPPLA 3394 Query: 3378 GIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXX 3437 G+AHLAGVLDDALL Q+ ERFRTTLAPKA+GA + Sbjct: 3395 GVAHLAGVLDDALLGQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGS 3454 Query: 3438 PGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDP 3497 PGQ+NYATANA+LDGL+A+RRAQGL ATGINFGPWGQGGMASSEAATANI+AQGLIPLDP Sbjct: 3455 PGQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATANISAQGLIPLDP 3514 Query: 3498 SAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQ 3557 SAAL ALAEV+ANG+GQAT+LKANWQRAAKVLGS+RPPILDLVLPSA GE TGDSELLKQ Sbjct: 3515 SAALAALAEVVANGTGQATILKANWQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQ 3574 Query: 3558 LMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGG 3617 LMEIP+PQRAGFVTEFLQREVQNFLRLA PPAA+SRFLDLGTDSLMAIELRNRLHSQFGG Sbjct: 3575 LMEIPVPQRAGFVTEFLQREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGG 3634 Query: 3618 KFTINATAVFDYPTIGGLAEYLVGQLPDAEA 3648 KFTINATAVFDYPTIGGLAEYLVGQLPDA+A Sbjct: 3635 KFTINATAVFDYPTIGGLAEYLVGQLPDADA 3665 >tr|A0QDK0|A0QDK0_MYCA1 Tax_Id=243243 SubName: Full=Tylactone synthase modules 4 & 5;[Mycobacterium avium] Length = 3679 Score = 5248 bits (13613), Expect = 0.0 Identities = 2681/3679 (72%), Positives = 3005/3679 (81%), Gaps = 63/3679 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M + E +P SFAI+GYAARFPGAA A+E+W +L +GR+A+S+VPKDRWD +EFFDPD Sbjct: 1 MSTVEGLRDPASSFAIVGYAARFPGAADADEFWRVLAEGRDAVSEVPKDRWDADEFFDPD 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFVDDVTGFDAPFFGMSARE RL+DPQHR+L+ETAWRAVEHSG APT Sbjct: 61 PDAPGKVVTRRAGFVDDVTGFDAPFFGMSAREARLLDPQHRLLLETAWRAVEHSGTAPTD 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LAN+NTGVF+G++THDYLGMASDELTY +IEAY AIGTS+AAAAGRISYRLGLQGPAVAV Sbjct: 121 LANTNTGVFIGISTHDYLGMASDELTYDQIEAYTAIGTSSAAAAGRISYRLGLQGPAVAV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQALRL ECDLALAGGANVLLTPATMITFS AHMLAPDGRCKTFDA Sbjct: 181 DTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSQAHMLAPDGRCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGV+VVKRLEDA+RDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA Sbjct: 241 AADGYVRGEGCGVLVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 +AL+RAG+ P DV YLEAHGTGTSLGDPIE QAAG VLGAGR PLLIGS KTNIGHL Sbjct: 301 EALQRAGIAPGDVDYLEAHGTGTSLGDPIEVQAAGAVLGAGREASRPLLIGSVKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LE+ LP+HL+F PSPHIPW+RL ++VV+E WQRNG+PR+AG Sbjct: 361 EAAAGIAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLAVQVVKEATAWQRNGRPRVAG 420 Query: 421 VSSFGFAGTNAHVILEEAP-----AVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGE 475 VSSFGFAGTNAHVILEEAP A PA P RR+ VLPLSARTP ALV++AGE Sbjct: 421 VSSFGFAGTNAHVILEEAPDGTGRAAVPPAAVRP-PGQRRFHVLPLSARTPAALVQIAGE 479 Query: 476 YRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRG 535 YRDWL AHP LAD+ TAG RAH E RAALVV+S SA ELL ALADDRPAPGL+RG Sbjct: 480 YRDWLSAHPDTALADLCLTAGAGRAHFEHRAALVVDSTGSAGELLAALADDRPAPGLLRG 539 Query: 536 ESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD 595 +APKTAWLFTGQGSQY GMARELFDTEPVFAET+ +CA +AD+LEKPLLDVIFD D Sbjct: 540 VCEDAPKTAWLFTGQGSQYAGMARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTD 599 Query: 596 ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDV 655 D +E+ LR T+YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQYSAACVAGV V Sbjct: 600 --DPASEATLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVLRV 657 Query: 656 EDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAK 715 EDGARLIAERGRLFGSLPAGGRM A F A R E LTDE+PSLSVAAYNGANTVLSGP + Sbjct: 658 EDGARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEFPSLSVAAYNGANTVLSGPGQ 717 Query: 716 DLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGS 775 +LE AVA L A+ VRCDWLDTSHAFHSALLDPILD+FES+A + ++ PQRILI NRTGS Sbjct: 718 ELEQAVARLTAEKVRCDWLDTSHAFHSALLDPILDEFESYANQFDFGPPQRILICNRTGS 777 Query: 776 ALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPAT 835 ALGRS +LDGAYWRRHARQPVEFAKSV TLAD+ C+VLLEIGP+PVLTA AL AWPDPAT Sbjct: 778 ALGRSVKLDGAYWRRHARQPVEFAKSVHTLADLGCKVLLEIGPQPVLTAAALRAWPDPAT 837 Query: 836 TPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFS 895 P+ +ASLR TADHRQITEA+A AY GHLPDF A P ARKLDLPTYPF+HRQ+WFS Sbjct: 838 APRAIASLRRNTADHRQITEALAEAYIVGHLPDFGAAVGP-ARKLDLPTYPFQHRQYWFS 896 Query: 896 DNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARH 955 + R QT++ +T AVRLLEDG+I ELA L+DG + D+ TL VL KLAA+H Sbjct: 897 EQRVPPGSQQTST-------QTTAVRLLEDGRIAELAELLDGASADQHTLDVLTKLAAQH 949 Query: 956 NQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQI 1015 NQQR + + RYEIRW+ W++VGDD AV DALTA GH+H+I Sbjct: 950 NQQRKSRSIAEDRYEIRWEKSTVPGPEAEAT--WLVVGDDDDAVAPLVDALTARGHQHRI 1007 Query: 1016 VALPGSDADEAQLVDTLRAASAGE--LYVVHIAAGDGAAAP-MRDLLRVQHRTLGGLRRL 1072 + LP SDADE +L LRAA+A E L + +AA D AP MR LLR+QHR L G RRL Sbjct: 1008 LVLPASDADEERLEIVLRAAAAEEAPLRIALVAALDSGTAPSMRSLLRMQHRVLAGTRRL 1067 Query: 1073 FRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLS-G 1131 FRAA AELR PIWLVTR QRVTD DTV P+QSCLWGFGRAA+LE P +WGGLADL+ G Sbjct: 1068 FRAAAAAELRQPIWLVTRGAQRVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQG 1127 Query: 1132 ADTEWPRLIARITSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVT 1188 + EW RL+ ++PRD GEDQIALRG +Y PRL RR+G+P+ L +R D TYLVT Sbjct: 1128 SAEEWSRLVRVASAPRDPAVGEDQIALRGSDIYVPRLTRRSGQPAAAALTLRADATYLVT 1187 Query: 1189 GGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAH 1248 GGLG+IGLE+AG+LA+ GA H+VLT RR P +Q+ C+VRVI ADVADAH Sbjct: 1188 GGLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRVIAADVADAH 1247 Query: 1249 DVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDL 1308 VARL+ V AELPP+AGIVHAAGEIGTTPLS L+DAE+DRVFAGKVWGAWHLSEA DL Sbjct: 1248 HVARLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAAADL 1307 Query: 1309 RTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMAD 1368 R LDFFVSTSSIASVWGG GQTAYGAANAFLDGLAWRLRE+GV +SVNFGPWAAGMAD Sbjct: 1308 R--LDFFVSTSSIASVWGGLGQTAYGAANAFLDGLAWRLREQGVNGISVNFGPWAAGMAD 1365 Query: 1369 AESRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRAFLSE 1427 +RARL QRG++TLSPA+ALAG+ADV+A QGVVA+IDW+RFLPLYQQAG+R+ L+E Sbjct: 1366 ENARARLAQRGIKTLSPADALAGLADVMATAAAQGVVARIDWTRFLPLYQQAGQRSLLAE 1425 Query: 1428 LESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIR 1487 L E+ LVE+L APVQQR+ L+T +LRNAVAEVTRVDA EIR Sbjct: 1426 LAREIPDFAPAPTPSGKTG----LVERLAGAPVQQRRKLMTEFLRNAVAEVTRVDAAEIR 1481 Query: 1488 DEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTN 1547 ++AGFFDLGMDSLMA+ELRR IEQGVGK IP TL MD+PRLSD A+YLL +VL L Q + Sbjct: 1482 EDAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGDVLDLRGQPD 1541 Query: 1548 VRQASTV-----TARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDID 1602 + A RTD+PIA+VA++CRFPGA DPE+FWELL+GGVDAIREVPEDR+DID Sbjct: 1542 AKPAPPAGTPAPAGRTDEPIAIVAMACRFPGAADPEAFWELLSGGVDAIREVPEDRFDID 1601 Query: 1603 EFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERA 1662 EFYDPDP+TPGK Y+R PEFFGISPREAVWI+PQQRL+LETVWEGLERA Sbjct: 1602 EFYDPDPETPGKMYSRFGGYLDQIDEFDPEFFGISPREAVWIDPQQRLVLETVWEGLERA 1661 Query: 1663 GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEG 1722 GY+P+ LRGSR+G+F GV ANEY+HLLSAES+DKIEPHFITGNALNAISGRVAFALG EG Sbjct: 1662 GYSPAALRGSRSGIFVGVGANEYSHLLSAESVDKIEPHFITGNALNAISGRVAFALGLEG 1721 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PAVAVDTACSS+LVAVHQACQAL SGDCDLALAGGVNVLLSPV+ +AASRARMLSPVGRC Sbjct: 1722 PAVAVDTACSSSLVAVHQACQALHSGDCDLALAGGVNVLLSPVSNIAASRARMLSPVGRC 1781 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 KTFDA+ADGYVRSEGCG+LVLKR+SDAVRDGDRVCAVIPAS+VNQDGASSGLTVPNGGAQ Sbjct: 1782 KTFDATADGYVRSEGCGILVLKRMSDAVRDGDRVCAVIPASAVNQDGASSGLTVPNGGAQ 1841 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QRLI L+RAGLSG DVDYLEAHGTGT LGDPIEVQ PLL+GSVKT Sbjct: 1842 QRLIATALSRAGLSGDDVDYLEAHGTGTALGDPIEVQAAGAVYGATRDTDRPLLIGSVKT 1901 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGH E+ASG AGLIKVVLSLQH +LPQSLHFE PSPHIPWD+LP+RV+D+ VPWQTNGR Sbjct: 1902 NIGHLEAASGVAGLIKVVLSLQHEMLPQSLHFETPSPHIPWDSLPLRVVDKAVPWQTNGR 1961 Query: 1963 VRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSP-QVLALSARSP 2021 RRAGVSSFGFTGTNAHVL+EEAP + +D P VL LSARSP Sbjct: 1962 PRRAGVSSFGFTGTNAHVLIEEAPQPVTTQDATPAAE-------SDARPVDVLPLSARSP 2014 Query: 2022 EALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXX 2081 EAL+ LA+RY +WL A P DI D+C T G GR+HFE+RAALVVDSV Sbjct: 2015 EALLALAQRYGEWLHAHPDADIGDLCFTVGAGRAHFEHRAALVVDSVRSAREALADLADN 2074 Query: 2082 XTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRP 2141 T GV RGE PTTAWLFTGQGSQYPGMARELFD +PVFA+TV +CA+AV +LPRP Sbjct: 2075 RTRPGVARGECTDPPTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCADAVDGLLPRP 2134 Query: 2142 LLDVLFATDRETAD----LLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYA 2197 L +V+FATD++T L++T+FAQPALFAVEMGLARLWQSW +EPDVVLGHSVGQYA Sbjct: 2135 LTEVIFATDKDTGGEAGKTLRNTAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYA 2194 Query: 2198 AACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNG 2257 AACVAGVFSL+DGARLMAERGR+FG LP+GGRMVAVFADA++VE++A + PRVSV AYNG Sbjct: 2195 AACVAGVFSLEDGARLMAERGRLFGGLPDGGRMVAVFADAQYVEELANDCPRVSVAAYNG 2254 Query: 2258 PNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPT 2317 PNTVLSGPG DLE+IV R +GIRC+WL TSHAFHSELLDPVLD PT Sbjct: 2255 PNTVLSGPGADLEQIVARGASDGIRCSWLETSHAFHSELLDPVLDEFESYAAHLDFAVPT 2314 Query: 2318 LPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGA 2377 LPLVCNRTG VLT +TPLDA+YWRRHSRQPVQFAESVRTVAALGC+VLMEIGPQPVLTGA Sbjct: 2315 LPLVCNRTGTVLTTETPLDARYWRRHSRQPVQFAESVRTVAALGCTVLMEIGPQPVLTGA 2374 Query: 2378 AVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTY 2437 AVQVWPEH+AAPRA+ SLRKGV DRRQIA+ LA+AYV GHRP+FAA+HR+PRR +ELPTY Sbjct: 2375 AVQVWPEHLAAPRAIVSLRKGVGDRRQIAEGLAAAYVSGHRPEFAALHRRPRRKLELPTY 2434 Query: 2438 PFQRRRFWPKASSIA-VDG-GTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYG 2495 PFQRRRFWPKAS IA +DG G AASG+LGS K+LASGD++YTSRLSVKSQPWLADHVIYG Sbjct: 2435 PFQRRRFWPKASGIAGIDGQGAAASGLLGSAKELASGDSVYTSRLSVKSQPWLADHVIYG 2494 Query: 2496 TVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIH 2555 TVVVPGATYAAMALAAVG PAR+++V+FYEPIILP+KASREVQL+LHP G SF++ Sbjct: 2495 TVVVPGATYAAMALAAVGPPARVQNVYFYEPIILPDKASREVQLSLHPLQEGG-WSFRVD 2553 Query: 2556 SRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLE 2615 SRPYG A+WSLNA+GTV AG + + AAD +D +D VIERL+R RPQ LF++FA+ E Sbjct: 2554 SRPYGVPDAEWSLNADGTV-VAGIEDEPAADP-ADHIDAVIERLDRNRPQLLFDSFAESE 2611 Query: 2616 LAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXX 2675 L WG TWS SLKSLW+GDGEAVGD+ VG ELAE LG+EPMHPVL+DLCTGV Sbjct: 2612 LEWGTTWSTSLKSLWMGDGEAVGDVTVGDELAEHLGTEPMHPVLLDLCTGVVFPAFPALL 2671 Query: 2676 XXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGG 2735 EQG NDL LPLRYGQV+L EKMPRRFYCR +W SALDSETQVF+++F+D GR LGG Sbjct: 2672 AAEQGFNDLLLPLRYGQVSLREKMPRRFYCRGKWRPSALDSETQVFDIDFIDRDGRHLGG 2731 Query: 2736 IREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAV---GTWLIAGFDELAA 2792 IREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPP PS D GTWLIAGFDEL A Sbjct: 2732 IREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPQPSNDGVANPSGTWLIAGFDELGA 2791 Query: 2793 KVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXI 2852 ++PGC+P DRNTD + G++L++A RG +G+VWR G + I Sbjct: 2792 QLPGCIPFDRNTDPESFGQLLARAEDRGGPVTGIVWRATQSGGRESSAESVARLETE--I 2849 Query: 2853 TNLLSAVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPA 2909 LL+AVHA Q G +VKLPGGLWIVTE GVA ESGEPVDPVQAALWG GRT +NEEPA Sbjct: 2850 AGLLTAVHALQNADGSAVKLPGGLWIVTERGVATESGEPVDPVQAALWGLGRTIVNEEPA 2909 Query: 2910 LHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGD 2969 L CRLVD DGS +AV P + EPE+AVRQGKLLASRLLPWARSGHL +PRG D Sbjct: 2910 LRCRLVDSDGSEQAVRSLAGLLGAP-LDEPELAVRQGKLLASRLLPWARSGHLAVPRGTD 2968 Query: 2970 FVLAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGD 3029 +VLAPTERGAIDNLRL E + P P EG VQVRVEA GLNFR+VLNVLGLYPGDPGP+GGD Sbjct: 2969 YVLAPTERGAIDNLRLIEQEAPPPAEGCVQVRVEAGGLNFREVLNVLGLYPGDPGPLGGD 3028 Query: 3030 FAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAAL 3089 FAGTVTQLG+GV+GLE+G RVYG MQGAFASRFNVP Q LAPIPDG+ AV+AATIPAAAL Sbjct: 3029 FAGTVTQLGSGVTGLEVGTRVYGFMQGAFASRFNVPVQLLAPIPDGVSAVDAATIPAAAL 3088 Query: 3090 TVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGVKY 3149 T RLAFDWAQLKPGD+VLIHAASGGVGLAAIQ+AQ+ GA VFATAST+KR+TLR+LGV+Y Sbjct: 3089 TARLAFDWAQLKPGDRVLIHAASGGVGLAAIQLAQRHGATVFATASTYKRATLRKLGVEY 3148 Query: 3150 VYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHE 3209 VYDSR+TDFADQILADT+GAGVDVVLNSLT+ GF+EAT++ATAQ GRF EIAKRDIW+ E Sbjct: 3149 VYDSRSTDFADQILADTDGAGVDVVLNSLTNEGFIEATVRATAQHGRFVEIAKRDIWTRE 3208 Query: 3210 QMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAF 3269 QMA ARPDIAYEIVALD +P+ I LLTEVSDG+A GEW PLPAEIYP+ EA++AF Sbjct: 3209 QMAAARPDIAYEIVALDWACVEQPEHIHALLTEVSDGLASGEWRPLPAEIYPLAEAKTAF 3268 Query: 3270 RRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRD 3329 RRMQQARHIGKI DRSYLITGGLGAIGLH AAYLAQLGAG+IVLTSRR Sbjct: 3269 RRMQQARHIGKIVLQMPKPLQPRGDRSYLITGGLGAIGLHLAAYLAQLGAGEIVLTSRRA 3328 Query: 3330 PDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDA 3389 PD +A RAID+ITER++CR+HT+AADVGD AQV LLARIRAELPPLAG+AHLAGVLDDA Sbjct: 3329 PDAAAWRAIDDITERYRCRVHTFAADVGDAAQVEQLLARIRAELPPLAGVAHLAGVLDDA 3388 Query: 3390 LLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAM 3449 LLS Q+PERFR LAPKA+GAS+ PGQANY+TANA Sbjct: 3389 LLSQQSPERFRVALAPKAFGASYLDHATRTDDLDFFIVSSSVSSLLGSPGQANYSTANAW 3448 Query: 3450 LDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALAEVIA 3509 LDGLVA R+A+GL ATG+N GPW QGGMASSEAA ANI AQGLIPL+P+AAL ALAEV+A Sbjct: 3449 LDGLVAARQARGLPATGVNLGPWAQGGMASSEAARANIGAQGLIPLEPTAALAALAEVVA 3508 Query: 3510 NGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGF 3569 NG+GQATV+KANWQRAAK+LG ARPPILDLVLPSA GEA+GDSELLKQL EIP+ QRA F Sbjct: 3509 NGTGQATVIKANWQRAAKLLGGARPPILDLVLPSAVGEASGDSELLKQLQEIPVAQRAAF 3568 Query: 3570 VTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDY 3629 +TEFLQREVQ FLRLA PPAA+SRFLDLGTDSLMA+ELRNRLHSQFGG FTINATAVFDY Sbjct: 3569 ITEFLQREVQGFLRLAQPPAATSRFLDLGTDSLMAVELRNRLHSQFGGAFTINATAVFDY 3628 Query: 3630 PTIGGLAEYLVGQLPDAEA 3648 PTIGGLAEYL GQLPDAE+ Sbjct: 3629 PTIGGLAEYLAGQLPDAES 3647 >tr|Q73XS9|Q73XS9_MYCPA Tax_Id=1770 SubName: Full=Putative uncharacterized protein;[Mycobacterium paratuberculosis] Length = 3679 Score = 5241 bits (13596), Expect = 0.0 Identities = 2678/3678 (72%), Positives = 3002/3678 (81%), Gaps = 63/3678 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M + E +P SFAI+GYAARFP AA A+E+W +L +GR+A+S+VPKDRWD +EFFDPD Sbjct: 1 MSTVEGLRDPASSFAIVGYAARFPDAADADEFWRVLAEGRDAVSEVPKDRWDADEFFDPD 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P PGKVVTRRAGFVDDVTGFDAPFFGMSARE RL+DPQHR+L+ETAWRAVEH G APT Sbjct: 61 PDAPGKVVTRRAGFVDDVTGFDAPFFGMSAREARLLDPQHRLLLETAWRAVEHCGTAPTD 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LAN+NTGVF+G++THDYLGMASDELTY +IEAY AIGTS+AAAAGRISYRLGLQGPAVAV Sbjct: 121 LANTNTGVFIGISTHDYLGMASDELTYDQIEAYTAIGTSSAAAAGRISYRLGLQGPAVAV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVAIHQACQALRL ECDLALAGGANVLLTPATMITFS AHMLAPDGRCKTFDA Sbjct: 181 DTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSQAHMLAPDGRCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGV+VVKRLEDA+RDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA Sbjct: 241 AADGYVRGEGCGVLVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 +AL+RAG+ P DV YLEAHGTGTSLGDPIE QAAG VLGAGR PLLIGS KTNIGHL Sbjct: 301 EALQRAGIAPGDVDYLEAHGTGTSLGDPIEVQAAGAVLGAGREASRPLLIGSVKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LE+ LP+HL+F PSPHIPW+RL ++VV+E WQRNG+PR+AG Sbjct: 361 EAAAGIAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLAVQVVKEATAWQRNGRPRVAG 420 Query: 421 VSSFGFAGTNAHVILEEAP-----AVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGE 475 VSSFGFAGTNAHVILEEAP A PA P RR+ VLPLSARTP ALV++AGE Sbjct: 421 VSSFGFAGTNAHVILEEAPDGTGRAAVPPAAVRP-PGQRRFHVLPLSARTPAALVQIAGE 479 Query: 476 YRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRG 535 YRDWL AHP LAD+ TAG RAH E RAALVV+S SA ELL ALADDRPAPGL+RG Sbjct: 480 YRDWLSAHPDTALADLCLTAGAGRAHFEHRAALVVDSTGSAGELLAALADDRPAPGLLRG 539 Query: 536 ESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD 595 +APKTAWLFTGQGSQY GMARELFDTEPVFAET+ +CA +AD+LEKPLLDVIFD D Sbjct: 540 VCEDAPKTAWLFTGQGSQYAGMARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTD 599 Query: 596 ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDV 655 D +E LR T+YAQPALFAVE+GLARLWQSWGFEPDVV+GHSVGQYSAACVAGV + Sbjct: 600 --DPASEETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVLRL 657 Query: 656 EDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAK 715 EDGARLIAERGRLFGSLPAGGRM A F A R E LTDE+PSLSVAAYNGANTVLSGP + Sbjct: 658 EDGARLIAERGRLFGSLPAGGRMVAAFAAAARVESLTDEFPSLSVAAYNGANTVLSGPGQ 717 Query: 716 DLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGS 775 +LE AVA L A+ VRCDWLDTSHAFHSAL DPILD+FES+A + ++ PQRILI NRTGS Sbjct: 718 ELEQAVARLTAEKVRCDWLDTSHAFHSALRDPILDEFESYANQFDFGPPQRILICNRTGS 777 Query: 776 ALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPAT 835 ALGRS +LDGAYWRRHARQPVEFAKSVRTLAD+ C+VLLEIGP+PVLTA AL AWPDPAT Sbjct: 778 ALGRSVKLDGAYWRRHARQPVEFAKSVRTLADLGCKVLLEIGPQPVLTAAALRAWPDPAT 837 Query: 836 TPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFS 895 P+ +ASLR TADHRQITEA+A AY GHLPDF A P ARKLDLPTYPF+HRQ+WFS Sbjct: 838 APRAIASLRRNTADHRQITEALAEAYIVGHLPDFGAAVGP-ARKLDLPTYPFQHRQYWFS 896 Query: 896 DNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARH 955 + R QT++ +T AVRLLEDG+I ELA L+DG +VD+ TL VL KLAA+H Sbjct: 897 EQRVPPGSQQTST-------QTTAVRLLEDGRIAELAELLDGASVDQHTLDVLTKLAAQH 949 Query: 956 NQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQI 1015 NQQR + + RYEIRW+ W++VGDD AV DALTA GH+H+I Sbjct: 950 NQQRKSRSIAEDRYEIRWEKSTVPGPEAEAT--WLVVGDDDDAVAPLVDALTARGHQHRI 1007 Query: 1016 VALPGSDADEAQLVDTLRAASAGE--LYVVHIAAGDGAAAP-MRDLLRVQHRTLGGLRRL 1072 + LP SDADE ++ LRAA+A E L + +AA D AP MR LLR+QHR L G RRL Sbjct: 1008 LVLPASDADEERVEIVLRAAAAEEAPLRIALVAALDSGTAPSMRSLLRMQHRVLAGTRRL 1067 Query: 1073 FRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLS-G 1131 FRAA AELR PIWLVTR QRVTD DTV P+QSCLWGFGRAA+LE P +WGGLADL+ G Sbjct: 1068 FRAAAAAELRQPIWLVTRGAQRVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQG 1127 Query: 1132 ADTEWPRLIARITSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVT 1188 + EW RL+ ++PRD GEDQIALRG +Y PRL RR+G+P+ L +R D TYLVT Sbjct: 1128 SAEEWSRLVRVASAPRDPAVGEDQIALRGSDIYVPRLTRRSGQPAAAALTLRADATYLVT 1187 Query: 1189 GGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAH 1248 GGLG+IGLE+AG+LA+ GA H+VLT RR P +Q+ C+VRVI ADVADAH Sbjct: 1188 GGLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRVIAADVADAH 1247 Query: 1249 DVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDL 1308 VARL+ V AELPP+AGIVHAAGEIGTTPLS L+DAE+DRVFAGKVWGAWHLSEA DL Sbjct: 1248 HVARLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAAADL 1307 Query: 1309 RTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMAD 1368 R LDFFVSTSSIASVWGG GQTAYGAANAFLDGLAWRLRE+GV +SVNFGPWAAGMAD Sbjct: 1308 R--LDFFVSTSSIASVWGGLGQTAYGAANAFLDGLAWRLREQGVNGISVNFGPWAAGMAD 1365 Query: 1369 AESRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRAFLSE 1427 +RARL QRG++TLSPA+ALAG+ADV+A QGVVA+IDW+RFLPLYQQAG+R+ L+E Sbjct: 1366 ENARARLAQRGIKTLSPADALAGLADVMATAAAQGVVARIDWTRFLPLYQQAGQRSLLAE 1425 Query: 1428 LESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIR 1487 L E+ LVE+L APVQQR+ L+T +LRNAVAEVTRVDA EIR Sbjct: 1426 LAREVPDFAPAPTPSGKTG----LVERLAGAPVQQRRKLMTEFLRNAVAEVTRVDAAEIR 1481 Query: 1488 DEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTN 1547 ++AGFFDLGMDSLMA+ELRR IEQGVGK IP TL MD+PRLSD A+YLL +VL L Q + Sbjct: 1482 EDAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGDVLDLRGQPD 1541 Query: 1548 VRQASTV-----TARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDID 1602 + A RTD+PIA+V+++CRFPGA DPE+FWELL+GGVDAIREVPEDR+DID Sbjct: 1542 AKPAPPAGTPAPAGRTDEPIAIVSMACRFPGAADPEAFWELLSGGVDAIREVPEDRFDID 1601 Query: 1603 EFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERA 1662 EFYDPDP+TPGK Y+R PEFFGISPREAVWI+PQQRL LETVWEGLERA Sbjct: 1602 EFYDPDPETPGKMYSRFGGYLDQIDEFEPEFFGISPREAVWIDPQQRLALETVWEGLERA 1661 Query: 1663 GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEG 1722 GY+P+ LRGSR+G+F GV ANEY+HLLSAES+DKIEPHFITGNALNAISGRVAFALG EG Sbjct: 1662 GYSPAALRGSRSGIFVGVGANEYSHLLSAESVDKIEPHFITGNALNAISGRVAFALGLEG 1721 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PAVAVDTACSS+LVAVHQACQAL SGDCDLALAGGVNVLLSPV+ +AASRARMLSPVGRC Sbjct: 1722 PAVAVDTACSSSLVAVHQACQALHSGDCDLALAGGVNVLLSPVSNIAASRARMLSPVGRC 1781 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 KTFDA+ADGYVRSEGCG+LVLKR+SDAVRDGDRVCAVIPAS+VNQDGASSGLTVPNGGAQ Sbjct: 1782 KTFDATADGYVRSEGCGILVLKRMSDAVRDGDRVCAVIPASAVNQDGASSGLTVPNGGAQ 1841 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QRLI L+RAGLSG DVDYLEAHGTGT LGDPIEVQ PLL+GSVKT Sbjct: 1842 QRLIATALSRAGLSGDDVDYLEAHGTGTALGDPIEVQAAGAVYGATRDTDRPLLIGSVKT 1901 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGH E+ASG AGLIKVVLSLQH +LPQSLHFE PSPHIPWD+LP+RV+D+ VPWQTNGR Sbjct: 1902 NIGHLEAASGVAGLIKVVLSLQHEMLPQSLHFETPSPHIPWDSLPLRVVDKAVPWQTNGR 1961 Query: 1963 VRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSP-QVLALSARSP 2021 RRAGVSSFGFTGTNAHVL+EEAP + +D P VL LSARSP Sbjct: 1962 PRRAGVSSFGFTGTNAHVLIEEAPQPVTTQHATPAAE-------SDARPVDVLPLSARSP 2014 Query: 2022 EALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXX 2081 EAL+ LA+RY +WL A P DI D+C T G GR+HFE+RAALVVDSV Sbjct: 2015 EALLALAQRYGEWLHAHPDADIGDLCFTVGAGRAHFEHRAALVVDSVRSAREALADLADN 2074 Query: 2082 XTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRP 2141 T GV RGE PTTAWLFTGQGSQYPGMARELFD +PVFA+TV +CA+AV +LPRP Sbjct: 2075 RTRPGVARGECTDPPTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCADAVDGLLPRP 2134 Query: 2142 LLDVLFATDRETAD----LLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYA 2197 L +V+FATD++T L++T+FAQPALFAVEMGLARLWQSW +EPDVVLGHSVGQYA Sbjct: 2135 LTEVIFATDKDTGGEAGKTLRNTAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYA 2194 Query: 2198 AACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNG 2257 AACVAGVFSL+DGARLMAERGR+FG LP+GGRMVAVFADA++VE++A + PRVSV AYNG Sbjct: 2195 AACVAGVFSLEDGARLMAERGRLFGGLPDGGRMVAVFADAQYVEELANDCPRVSVAAYNG 2254 Query: 2258 PNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPT 2317 PNTVLSGPG DLE+IV R +GIRC+WL TSHAFHSELLDPVLD PT Sbjct: 2255 PNTVLSGPGADLEQIVARGASDGIRCSWLETSHAFHSELLDPVLDEFESYAAHLDFAVPT 2314 Query: 2318 LPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGA 2377 LPLVCNRTG VLT +TPLDA+YWRRHSRQPVQFAESVRTVAALGC+VLMEIGPQPVLTGA Sbjct: 2315 LPLVCNRTGTVLTTETPLDARYWRRHSRQPVQFAESVRTVAALGCTVLMEIGPQPVLTGA 2374 Query: 2378 AVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTY 2437 AVQVWPEH+AAPRA+ SLRKGV DRRQIA+ LA+AYV GHRP+FAA+HR+PRR +ELPTY Sbjct: 2375 AVQVWPEHLAAPRAIVSLRKGVGDRRQIAEGLAAAYVSGHRPEFAALHRRPRRKLELPTY 2434 Query: 2438 PFQRRRFWPKASSIA-VDG-GTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYG 2495 PFQRRRFWPKAS IA +DG G AASG+LGS K+LASGD +YTSRLSVKSQPWLADHVIYG Sbjct: 2435 PFQRRRFWPKASGIAGIDGQGAAASGLLGSAKELASGDCVYTSRLSVKSQPWLADHVIYG 2494 Query: 2496 TVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIH 2555 TVVVPGATYAAMALAAVG PAR+++V+FYEPIILP+KASREVQL+LHP G SF++ Sbjct: 2495 TVVVPGATYAAMALAAVGPPARVQNVYFYEPIILPDKASREVQLSLHPLQEGG-WSFRVD 2553 Query: 2556 SRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLE 2615 SRPYG A+WSLNA+GTV AG + + AAD +D +D VIERL+R RPQ LF++FA+ E Sbjct: 2554 SRPYGVPDAEWSLNADGTV-VAGIEDEPAADP-ADHIDAVIERLDRSRPQLLFDSFAESE 2611 Query: 2616 LAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXX 2675 L WG TWS SLKSLW+GDGEAVGD+ VG ELAE LG+EPMHPVL+DLCTGV Sbjct: 2612 LEWGTTWSTSLKSLWMGDGEAVGDVTVGDELAEHLGTEPMHPVLLDLCTGVVFPAFPALL 2671 Query: 2676 XXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGG 2735 EQG NDL LPLRYGQV+L EKMPRRFYCR +W SALDSETQVF+++F+D GR LGG Sbjct: 2672 AAEQGFNDLLLPLRYGQVSLREKMPRRFYCRGKWRPSALDSETQVFDIDFIDRDGRHLGG 2731 Query: 2736 IREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAV---GTWLIAGFDELAA 2792 IREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPP PS D GTWLIAGFDELAA Sbjct: 2732 IREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPQPSNDGGANPSGTWLIAGFDELAA 2791 Query: 2793 KVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXI 2852 ++PGC+P DRNTD + G++L++A RG +G+VWR G + I Sbjct: 2792 QLPGCIPFDRNTDPESFGQLLARAEDRGGPVTGIVWRATQSGGQESSAESVARLETE--I 2849 Query: 2853 TNLLSAVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPA 2909 LL+AVHA Q G +VKLPGGLWIVTE GVA ESGEPVDPVQAALWG GRT +NEEPA Sbjct: 2850 AGLLTAVHALQNADGSAVKLPGGLWIVTERGVATESGEPVDPVQAALWGLGRTIVNEEPA 2909 Query: 2910 LHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGD 2969 L CRLVD DGS +AV P + EPE+AVRQGKLLASRLLPWARSGHL +PRG D Sbjct: 2910 LRCRLVDSDGSEQAVRSLAGLLGAP-LDEPELAVRQGKLLASRLLPWARSGHLAVPRGTD 2968 Query: 2970 FVLAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGD 3029 +VLAPTERGAIDNLRL E + P P EG VQVRVEA GLNFR+VLNVLGLYPGDPGP+GGD Sbjct: 2969 YVLAPTERGAIDNLRLIEQEAPPPAEGCVQVRVEAGGLNFREVLNVLGLYPGDPGPLGGD 3028 Query: 3030 FAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAAL 3089 FAGTVTQLG+GV+GLE+G RVYG MQGAFASRFNVP Q LAPIPDG+ AV+AATIPAAAL Sbjct: 3029 FAGTVTQLGSGVTGLEVGTRVYGFMQGAFASRFNVPVQLLAPIPDGVSAVDAATIPAAAL 3088 Query: 3090 TVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGVKY 3149 T RLAFDWAQLKPGD+VLIHAASGGVGLAAIQ+AQ+ GA VFATAST+KR+TLR+LGV+Y Sbjct: 3089 TARLAFDWAQLKPGDRVLIHAASGGVGLAAIQLAQRHGATVFATASTYKRATLRKLGVEY 3148 Query: 3150 VYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHE 3209 VYDSR+TDFADQILADT+GAGVDVVLNSLT+ GF+EAT++ATAQ GRF EIAKRDIW+ E Sbjct: 3149 VYDSRSTDFADQILADTDGAGVDVVLNSLTNEGFIEATVRATAQHGRFVEIAKRDIWTRE 3208 Query: 3210 QMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAF 3269 QMA ARPDIAYEIVALD +P+ I LLTEVSDG+A GEW PLPAEIYP+ EA++AF Sbjct: 3209 QMAAARPDIAYEIVALDWACVEQPEHIHALLTEVSDGLASGEWRPLPAEIYPLAEAKTAF 3268 Query: 3270 RRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRD 3329 RRMQQARHIGKI DRSYLITGGLGAIGLH AAYLAQLGAG+IVLTSRR Sbjct: 3269 RRMQQARHIGKIVLQMPKPLQPRGDRSYLITGGLGAIGLHLAAYLAQLGAGEIVLTSRRA 3328 Query: 3330 PDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDA 3389 PD +A+RAID+ITER++CR+HT+AADVGD AQV LLARIRAELPPLAG+AHLAGVLDDA Sbjct: 3329 PDAAARRAIDDITERYRCRVHTFAADVGDAAQVEQLLARIRAELPPLAGVAHLAGVLDDA 3388 Query: 3390 LLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAM 3449 LLS Q+PERFR LAPKA+GAS+ PGQANY+TANA Sbjct: 3389 LLSQQSPERFRVALAPKAFGASYLDHATRTDDLDFFIVSSSVSSLLGSPGQANYSTANAW 3448 Query: 3450 LDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALAEVIA 3509 LDGLVA R+A+GL ATG+N GPW QGGMASSEAA ANI AQGLIPL+P+AAL ALAEV+A Sbjct: 3449 LDGLVAARQARGLPATGVNLGPWAQGGMASSEAARANIGAQGLIPLEPTAALAALAEVVA 3508 Query: 3510 NGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGF 3569 NG+GQATV+KANWQRAAK+LG ARPPILDLVLPSA GEA+GDSELLKQL EIP+ QRA F Sbjct: 3509 NGTGQATVIKANWQRAAKLLGDARPPILDLVLPSAVGEASGDSELLKQLQEIPVAQRAAF 3568 Query: 3570 VTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDY 3629 +TEFLQREVQ FLRLA PPAA+SRFLDLGTDSLMA+ELRNRLHSQFGG FTINATAVFDY Sbjct: 3569 ITEFLQREVQGFLRLAQPPAATSRFLDLGTDSLMAVELRNRLHSQFGGAFTINATAVFDY 3628 Query: 3630 PTIGGLAEYLVGQLPDAE 3647 PTIGGLAEYL GQLPDAE Sbjct: 3629 PTIGGLAEYLAGQLPDAE 3646 >tr|A1T3U1|A1T3U1_MYCVP Tax_Id=350058 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium vanbaalenii] Length = 3696 Score = 4578 bits (11875), Expect = 0.0 Identities = 2360/3661 (64%), Positives = 2730/3661 (74%), Gaps = 50/3661 (1%) Query: 14 FAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAG 73 +AI+GYA RFPGAA A+E+W +LR GR+AIS+VP+DRWD +EFFD DP GK+VTRRAG Sbjct: 29 YAIVGYALRFPGAADADEFWDVLRGGRDAISEVPQDRWDADEFFDADPEAAGKMVTRRAG 88 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 FV+DV GFDAPFFG+SARE MDPQHR+L+ETAWRAVEHSG AP++LA + TGVF+GL+ Sbjct: 89 FVEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTRTGVFMGLS 148 Query: 134 THDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQ 193 THDYLGM +D LT+ IEAY+ GTS AAA GRISYRLGLQGPAVAVDTACSSSLVA+HQ Sbjct: 149 THDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQGPAVAVDTACSSSLVAVHQ 208 Query: 194 ACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGV 253 ACQALRL ECD+ALAGG NVLL+PATMI FS A MLAPDGRCKTFDA ADGYVRGEGCGV Sbjct: 209 ACQALRLAECDVALAGGVNVLLSPATMINFSRARMLAPDGRCKTFDATADGYVRGEGCGV 268 Query: 254 VVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADV 313 VVVKRL DA+R GDRIRAVIRGSA+NQDGASGGLTVPNG AQQRVIADAL AGL ADV Sbjct: 269 VVVKRLADAIRHGDRIRAVIRGSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADV 328 Query: 314 GYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXX 373 YLEAHGTGT LGDPIE QAAG VLG GR P+ PLLIGS KTNIGHLE Sbjct: 329 DYLEAHGTGTPLGDPIEVQAAGAVLGVGREPDRPLLIGSVKTNIGHLEAASGIAGLLKVI 388 Query: 374 XXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAHV 433 LE++ LPKHLNF +PSPHIPW RLP+ +V + VPW R+G+ R+AG+SSFGF+GTNAHV Sbjct: 389 LSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTRSGRSRVAGISSFGFSGTNAHV 448 Query: 434 ILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSH 493 ++EEAP P + +LPLSARTP+AL A R WL A+P A D+ Sbjct: 449 LVEEAPRADRAGAAPQPAAPGGFGMLPLSARTPDALAATAHRLRTWLAANPDASWPDLCF 508 Query: 494 TAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQGSQ 553 TA R+HL RAALVV+SR S ELLGALA+DRP PGL RGE + PKTAWLFTGQGSQ Sbjct: 509 TAAVGRSHLRHRAALVVDSRSSVEELLGALAEDRPGPGLARGECGDPPKTAWLFTGQGSQ 568 Query: 554 YPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYAQP 613 YPGM RELFDTEPV+ E + +CAEAVAD+LE+PLLDV+FDAD + LRHT+YAQP Sbjct: 569 YPGMGRELFDTEPVYREVMTRCAEAVADVLERPLLDVVFDADGGEA-----LRHTSYAQP 623 Query: 614 ALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGSLP 673 AL+AVE+GLARLWQSWG EPDVV+GHSVGQY+AACVAGV +EDGA L+AERGRLFGSLP Sbjct: 624 ALYAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLFGSLP 683 Query: 674 AGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVADGVRCDW 733 GGRMAAVF +R E T + P LSVAAYNG NTVLSGPA DLE AVA A GVRCDW Sbjct: 684 EGGRMAAVFAPADRVESCTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAGFSAAGVRCDW 743 Query: 734 LDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHAR 793 LDTSHAFHSALLDP+L++FES A + E+ PQR L+ NR+G L R RLDG YWRRHAR Sbjct: 744 LDTSHAFHSALLDPVLEEFESCADRFEFGTPQRTLVCNRSGEVLSRHARLDGQYWRRHAR 803 Query: 794 QPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTADHRQI 853 QPV FA+SVRTLAD+ CR+L+EIGP+PVLTA A+ WP T P+V AS+R +D RQI Sbjct: 804 QPVRFAESVRTLADLGCRLLMEIGPQPVLTAAAMRTWPGTVTAPRVAASMRRKGSDRRQI 863 Query: 854 TEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVT 913 TEA+A AY AGH P+ A + R LDLPTYPF+HR +WF +A T Sbjct: 864 TEALAQAYVAGHRPETAARQHGRGRLLDLPTYPFQHRAYWFPQGQARTAPTD-------- 915 Query: 914 PHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRW 973 P T+ VR L++ +I+ELAAL+DG T QT+ VL+KLAARH QQR DARY+IRW Sbjct: 916 PVHTETVRFLDEERIDELAALLDGPTGSAQTVDVLSKLAARHRQQRGAQSIADARYQIRW 975 Query: 974 D--XXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDT 1031 + W+LV D+ A A+ L GH + IV LPGSDAD A + Sbjct: 976 EKSEAPGAARPTTEATTWLLVTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPAEEA 1035 Query: 1032 LRA-ASAGELYVVHIAAGDGAAAPMRDLLR-VQHRTLGGLRRLFRAANDAELRSPIWLVT 1089 LRA S +++++AA + + L +QHR L RRLF+ A A R+PIWL+T Sbjct: 1036 LRATVSQPRPHILYLAALEEPGGSAAETLGWMQHRVLAAARRLFQLAATAGARAPIWLIT 1095 Query: 1090 RDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADT-EWPRLIARITSPRD 1148 QR+T +TV P Q+ LWGFGRAAALE P +WGGLAD++ D EW LI I + Sbjct: 1096 AGAQRITGDETVEPAQTSLWGFGRAAALEQPELWGGLADVTTGDAEEWSALIDHIVAAPT 1155 Query: 1149 GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAG 1208 EDQIA+RG ++ RL R + + L +R + TYLVTGGLGA+GLEVA +LASHGAG Sbjct: 1156 SEDQIAVRGREIHVARLTRCAEKANAAALELRREATYLVTGGLGALGLEVAEFLASHGAG 1215 Query: 1209 HVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIV 1268 H+VLT RR E++ C V V TADVAD DVARL +T+ +ELPPLAGIV Sbjct: 1216 HLVLTGRRSASDTVRQRIDAMRERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIV 1275 Query: 1269 HAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGF 1328 HAAGEIGT+PL LDDAE+DRVFAGKVWGA +L E + D+ LDFF++TSSIASVWG Sbjct: 1276 HAAGEIGTSPLRTLDDAEMDRVFAGKVWGAVYLCEEVADM--GLDFFLATSSIASVWGSH 1333 Query: 1329 GQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEA 1388 GQTAYGAANAFLDGLA LR RG+ +SVNFGPWAAGMADA++R +L +RGV+TL+PA+A Sbjct: 1334 GQTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAKAREQLSRRGVKTLAPADA 1393 Query: 1389 LAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXX 1447 LAGMADV+ A VVA+IDW+ FLP+YQ RRAFLS+LE E+ Sbjct: 1394 LAGMADVIAASTAHAVVARIDWATFLPVYQLQRRRAFLSQLEREV--PDVPDASAPAPSG 1451 Query: 1448 XXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRR 1507 VE+LT APV+QR+ L+ YLR AVAEVTRVDA EIRDEAGFFDLGMDSLMA+ELRR Sbjct: 1452 TTRFVEELTLAPVEQRRKLVLEYLRAAVAEVTRVDAAEIRDEAGFFDLGMDSLMAIELRR 1511 Query: 1508 RIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAV 1567 R+EQG+GK++PVTL MDHP LSDAA+Y+L +VLGL E T + + T RTDDPIA+V + Sbjct: 1512 RLEQGLGKELPVTLAMDHPHLSDAAEYVLGDVLGLSEHTVAQPDTPSTVRTDDPIAIVGM 1571 Query: 1568 SCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXX 1627 +CRFPGA D ++FW +LA G D IRE+P+DR+DI+EFYDPDP+ GK Y+R Sbjct: 1572 ACRFPGADDTDAFWSVLAEGADLIREIPDDRFDINEFYDPDPEAAGKIYSRYGGFLDGVD 1631 Query: 1628 XXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAH 1687 PEFFGISPREAVWI+PQQRL+LET WEGLERAGY+ + LRGSR+GV+ GV ANEY+H Sbjct: 1632 GFDPEFFGISPREAVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGVYVGVGANEYSH 1691 Query: 1688 LLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQS 1747 LLS S+D IE FITGNALN I+GRV+F LG EGPAVAVDTACSS+LVAVHQACQ LQS Sbjct: 1692 LLSGGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVAVDTACSSSLVAVHQACQGLQS 1751 Query: 1748 GDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLS 1807 GDCDLALAGGVNVLLSP T +A SRARMLSP GRCKTFDA+ADGYVR EGCG+LVLKRLS Sbjct: 1752 GDCDLALAGGVNVLLSPATTIATSRARMLSPDGRCKTFDAAADGYVRGEGCGILVLKRLS 1811 Query: 1808 DAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHG 1867 DAVRDGDR+ AVI S+VNQDGAS GLTVPNGGAQQR+I A L RAGLSG+D+DYLEAHG Sbjct: 1812 DAVRDGDRIQAVIRGSAVNQDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHG 1871 Query: 1868 TGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGV 1927 TGT LGDPIEVQ PLLMGSVKTN+GH ESASG AGLIKVVLSLQH + Sbjct: 1872 TGTSLGDPIEVQAAGAVLGAGRDPDRPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHEM 1931 Query: 1928 LPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPP 1987 LP+ LHF+ PSPHIPWD L VRV+ EP PW+ +GR RRAGVSSFGF+GTNAHV++EE P Sbjct: 1932 LPRHLHFKTPSPHIPWDRLAVRVVAEPTPWRADGRPRRAGVSSFGFSGTNAHVVLEEPPA 1991 Query: 1988 Q---LHXXXXXXXXXXXXXXXGTDDSPQ-VLALSARSPEALVELARRYDDWLSATPGLDI 2043 Q L T P VL +SARSPEAL LARRY+ WL+A P DI Sbjct: 1992 QSADLRQPPTDGKDGAAGLESATAPEPAGVLPISARSPEALTALARRYESWLTAHPDADI 2051 Query: 2044 ADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFT 2103 ADVC+TAG GRSHFE+RAALVVDSV G VRG P TAWLFT Sbjct: 2052 ADVCYTAGAGRSHFEHRAALVVDSVDGARDLLAGLAEDRLGPGAVRGVCGDPPKTAWLFT 2111 Query: 2104 GQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFA 2163 GQGSQYPGMARELFDT+PVF TV +CAEA+ D LPRPLL+VLF TD + L+HTS+A Sbjct: 2112 GQGSQYPGMARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDNGQTLRHTSYA 2171 Query: 2164 QPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGS 2223 QPALFA+EMGLARLWQ+ IEPDVVLGHSVGQYAAACVAGVF L+DGARL+A+RGR+FG Sbjct: 2172 QPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFGLEDGARLVADRGRLFGG 2231 Query: 2224 LPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFEDEGIRC 2283 LP GGRMVAVF DAE VE A EFP+VSV AYNGPNTVL+GP DLE+IV EGIR Sbjct: 2232 LPVGGRMVAVFTDAEVVEDFADEFPQVSVAAYNGPNTVLAGPASDLEQIVAGCSGEGIRT 2291 Query: 2284 TWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRH 2343 TWL TSHAFHS LLDPVLD PT PLVCNRTGAV+TG +DAQYWRRH Sbjct: 2292 TWLDTSHAFHSALLDPVLDEFESCAARLAYAAPTRPLVCNRTGAVVTGPGVIDAQYWRRH 2351 Query: 2344 SRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRR 2403 +RQPVQFAESVRT+A LGCSVLMEIGPQP L AA++VWPE A PRA+ SLRKG RR Sbjct: 2352 ARQPVQFAESVRTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIPSLRKGPDARR 2411 Query: 2404 QIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAASGIL 2463 Q+A+A+A+AY+ GHR DF P R + LPTYPFQ R +WPK + I D G++ SG+L Sbjct: 2412 QLAEAVAAAYIAGHRLDFTGHDGGPHRRLPLPTYPFQHRSYWPKTAGIRSD-GSSGSGLL 2470 Query: 2464 GSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARLKDVFF 2523 GS +DLASGD ++TSRLSVK+QPWL+DHVIYGTVVVPGATYAAMALAA+ TPAR+++VFF Sbjct: 2471 GSAQDLASGDIVHTSRLSVKTQPWLSDHVIYGTVVVPGATYAAMALAAMPTPARVQEVFF 2530 Query: 2524 YEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDA 2583 YEPIIL +K SREVQL LH D +F++HSRPYG+R ADWS NA GTV A DA Sbjct: 2531 YEPIILGDKDSREVQLMLHRTDDADGWTFEVHSRPYGDRDADWSRNASGTV--AAGVGDA 2588 Query: 2584 AADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVG 2643 A D +DPVD IERL R RPQ LF+ FAD +LAWGP W SL+SLW+G GEAVGDI VG Sbjct: 2589 APDAAADPVDNAIERLTRTRPQQLFDAFADNDLAWGPAWCSSLRSLWVGTGEAVGDIAVG 2648 Query: 2644 AELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRF 2703 AEL E LG EP+HPVL+DLCTG+ +LFLPLRYG+V + E+MPRRF Sbjct: 2649 AELGEHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRYGRVEVRERMPRRF 2708 Query: 2704 YCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYT 2763 YCRARW +DSETQVF+L+F+D GR LGGIREFTVKRAPREALLRGLG DATRL+Y Sbjct: 2709 YCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIREFTVKRAPREALLRGLGADATRLIYR 2768 Query: 2764 LGWHEVPPPPSADDAVG---TWLIAGFDELAAKVPGCVPI--DRNTDLQVLGEVL----- 2813 +GW E PP D A+G TWL+AG D LA VPG + I DR D G V+ Sbjct: 2769 VGWRETSPPVRDDGALGPSSTWLVAGLDALADDVPGSIRIGFDRIWDPDRDGRVVLDPAD 2828 Query: 2814 --------SQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGP 2865 + A R A +GVV T + I ++L AVH+ Sbjct: 2829 DEHWRRLFALADERRAPVAGVVLG-VTGRARPEEPSADFAARLEAQIRDVLGAVHSLSAL 2887 Query: 2866 SVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVD 2925 K GLWIVTE VA E+GEPVDPVQ+ALWG GRT I EEP L C LVD DGS +A Sbjct: 2888 GAKPAAGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLLVDLDGSEDAGP 2947 Query: 2926 XXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRL 2985 PG EPE+A+RQG+LL RLLPW+RSG L +PRG D+VLAPTERG +DNLR+ Sbjct: 2948 ALARLLGAPG-DEPELALRQGRLLVPRLLPWSRSGQLAIPRGTDYVLAPTERGVLDNLRV 3006 Query: 2986 TETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLE 3045 +ET+V P EG+VQVRVEAAGLNFRDVLN LGLYPGDPGPIGG+ AG VT G V G + Sbjct: 3007 SETEVTAPPEGHVQVRVEAAGLNFRDVLNALGLYPGDPGPIGGELAGVVTAPGPDVDGFD 3066 Query: 3046 IGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAFDWAQLKPGDK 3105 +GQRV+G GAFASR NVP QFLAP+P+GI AV AAT PAA LT LAFDWA L+ GD+ Sbjct: 3067 VGQRVFGFAVGAFASRVNVPVQFLAPVPEGISAVAAATTPAAVLTAGLAFDWAALRAGDR 3126 Query: 3106 VLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGVKYVYDSRTTDFADQILAD 3165 VLIHAASGGVGLAA+Q+A+Q GA VFATAS +KR LR +GV +VYDSRTTDFADQILAD Sbjct: 3127 VLIHAASGGVGLAAVQLARQRGATVFATASGYKRPMLRAMGVDHVYDSRTTDFADQILAD 3186 Query: 3166 TNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVAL 3225 T+GAGVDVVLNSLT+ GFV AT++ATA+ GRFAEIAKRDIWS EQMA ARPDI YE++AL Sbjct: 3187 TDGAGVDVVLNSLTNDGFVAATVRATARNGRFAEIAKRDIWSPEQMAAARPDIDYEVLAL 3246 Query: 3226 DTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXX 3285 D VM +PDRI+ LL +++D +ARGE PLP E YP+ EA +AFRRMQQARH GKI Sbjct: 3247 DAVMQQDPDRIQLLLADLADSLARGETAPLPFEAYPLAEATTAFRRMQQARHTGKIILQM 3306 Query: 3286 XXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERH 3345 DRSYLITGGLGA+GLH AAYLAQLGAGDIVLT RR PD + +RAI EI ER+ Sbjct: 3307 PKPLQPHGDRSYLITGGLGALGLHAAAYLAQLGAGDIVLTGRRMPDAATERAISEIAERY 3366 Query: 3346 KCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAP 3405 CRIHT+AADVGDE+ V DLL RIR ELPPLAG+AHLAGVLDDALL Q+PERFRTTLAP Sbjct: 3367 HCRIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQQSPERFRTTLAP 3426 Query: 3406 KAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVAT 3465 KA+GA H PGQANYATANA+LDGLVA R+A+GL AT Sbjct: 3427 KAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANYATANAVLDGLVAHRKARGLPAT 3486 Query: 3466 GINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRA 3525 G+N+GPW QGGMA+S+AA AN+ AQGLIPL+P+AAL+AL E++A+G A VLKANWQRA Sbjct: 3487 GVNWGPWAQGGMATSDAARANLGAQGLIPLEPTAALNALGEIVAHGIASAVVLKANWQRA 3546 Query: 3526 AKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA 3585 AK+LG+ RPPILD VLPSA GDS LLKQL ++P QR FVTE LQRE+Q L LA Sbjct: 3547 AKLLGATRPPILDHVLPSAVAAGPGDSALLKQLQDVPEAQRGSFVTEHLQRELQQILGLA 3606 Query: 3586 SPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPD 3645 PPAA+ RFL+LG DSLMA+ELRNRL QFG FTI ATAVFDYPTIG LAEYL Q P+ Sbjct: 3607 QPPAATGRFLELGMDSLMAVELRNRLVGQFGSGFTITATAVFDYPTIGALAEYLAAQTPE 3666 Query: 3646 A 3646 + Sbjct: 3667 S 3667 Score = 1036 bits (2680), Expect = 0.0 Identities = 528/887 (59%), Positives = 633/887 (71%), Gaps = 11/887 (1%) Query: 1560 DPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRX 1619 D A+V + RFPGA D + FW++L GG DAI EVP+DRWD DEF+D DP+ GK TR Sbjct: 27 DGYAIVGYALRFPGAADADEFWDVLRGGRDAISEVPQDRWDADEFFDADPEAAGKMVTRR 86 Query: 1620 XXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTG 1679 FFG+S REA++++PQ RL+LET W +E +G APS L G+RTGVF G Sbjct: 87 AGFVEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTRTGVFMG 146 Query: 1680 VAANEYAHLLSAE-SIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAV 1738 ++ ++Y +L+ + D IE + TG + A GR+++ LG +GPAVAVDTACSS+LVAV Sbjct: 147 LSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQGPAVAVDTACSSSLVAV 206 Query: 1739 HQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGC 1798 HQACQAL+ +CD+ALAGGVNVLLSP T++ SRARML+P GRCKTFDA+ADGYVR EGC Sbjct: 207 HQACQALRLAECDVALAGGVNVLLSPATMINFSRARMLAPDGRCKTFDATADGYVRGEGC 266 Query: 1799 GVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGA 1858 GV+V+KRL+DA+R GDR+ AVI S+VNQDGAS GLTVPNG AQQR+I L AGL+ A Sbjct: 267 GVVVVKRLADAIRHGDRIRAVIRGSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAA 326 Query: 1859 DVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIK 1918 DVDYLEAHGTGTPLGDPIEVQ PLL+GSVKTNIGH E+ASG AGL+K Sbjct: 327 DVDYLEAHGTGTPLGDPIEVQAAGAVLGVGREPDRPLLIGSVKTNIGHLEAASGIAGLLK 386 Query: 1919 VVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNA 1978 V+LSL+H VLP+ L+F +PSPHIPW+ LPVR++D+PVPW +GR R AG+SSFGF+GTNA Sbjct: 387 VILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTRSGRSRVAGISSFGFSGTNA 446 Query: 1979 HVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSAT 2038 HVLVEEAP +L LSAR+P+AL A R WL+A Sbjct: 447 HVLVEEAP--------RADRAGAAPQPAAPGGFGMLPLSARTPDALAATAHRLRTWLAAN 498 Query: 2039 PGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTT 2098 P D+C TA VGRSH +RAALVVDS G+ RGE P T Sbjct: 499 PDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELLGALAEDRPGPGLARGECGDPPKT 558 Query: 2099 AWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQ 2158 AWLFTGQGSQYPGM RELFDT+PV+ + + +CAEAVAD+L RPLLDV+F D + + L+ Sbjct: 559 AWLFTGQGSQYPGMGRELFDTEPVYREVMTRCAEAVADVLERPLLDVVF--DADGGEALR 616 Query: 2159 HTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERG 2218 HTS+AQPAL+AVEMGLARLWQSW IEPDVVLGHSVGQYAAACVAGV L+DGA L+AERG Sbjct: 617 HTSYAQPALYAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERG 676 Query: 2219 RMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFED 2278 R+FGSLPEGGRM AVFA A+ VE + P +SV AYNG NTVLSGP DLE V F Sbjct: 677 RLFGSLPEGGRMAAVFAPADRVESCTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAGFSA 736 Query: 2279 EGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQ 2338 G+RC WL TSHAFHS LLDPVL+ P LVCNR+G VL+ LD Q Sbjct: 737 AGVRCDWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRTLVCNRSGEVLSRHARLDGQ 796 Query: 2339 YWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKG 2398 YWRRH+RQPV+FAESVRT+A LGC +LMEIGPQPVLT AA++ WP + APR AS+R+ Sbjct: 797 YWRRHARQPVRFAESVRTLADLGCRLLMEIGPQPVLTAAAMRTWPGTVTAPRVAASMRRK 856 Query: 2399 VADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFW 2445 +DRRQI +ALA AYV GHRP+ AA R ++LPTYPFQ R +W Sbjct: 857 GSDRRQITEALAQAYVAGHRPETAARQHGRGRLLDLPTYPFQHRAYW 903 >tr|D5PHA5|D5PHA5_9MYCO Tax_Id=525368 SubName: Full=Putative uncharacterized protein; Flags: Fragment;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 2534 Score = 3458 bits (8966), Expect = 0.0 Identities = 1772/2542 (69%), Positives = 2011/2542 (79%), Gaps = 36/2542 (1%) Query: 1126 LADLS-GADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT 1184 LADLS G EW RLI ++ + GEDQIALR VY PRL RR G P+ PL +R D T Sbjct: 1 LADLSEGGAEEWSRLIGQVAAGPRGEDQIALRDHGVYIPRLSRRAGRPATPPLVLRGDAT 60 Query: 1185 YLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADV 1244 YLVTGGLG +GLE+AGYLA HGA H+VLTSRR P E C++RVITADV Sbjct: 61 YLVTGGLGGVGLEIAGYLADHGARHLVLTSRRAPGTAVQQRLDAIREGSDCEIRVITADV 120 Query: 1245 ADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEA 1304 A+ HDVARL+ TV A+LPPLAGIVHAAGE+GTTPL LDDAEVDRVFAGKVWGAW+LSEA Sbjct: 121 ANPHDVARLLATVEAQLPPLAGIVHAAGEMGTTPLRALDDAEVDRVFAGKVWGAWNLSEA 180 Query: 1305 LTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAA 1364 +L LDFF+STSSIASVWG FGQTAYGAANAFLDGL+WRLRE+GV VSVNFGPW+A Sbjct: 181 AAEL--SLDFFLSTSSIASVWGSFGQTAYGAANAFLDGLSWRLREQGVPGVSVNFGPWSA 238 Query: 1365 GMADAESRARLEQRGVRTLSPAEALAGMAD-VVAGPVQGVVAKIDWSRFLPLYQQAGRRA 1423 GMAD E+RARLEQRGVRTL PA+ALAGMA+ +VA GVVA+IDW+RFLPLYQQAG+R+ Sbjct: 239 GMADEEARARLEQRGVRTLPPADALAGMAEFLVASAAHGVVARIDWARFLPLYQQAGKRS 298 Query: 1424 FLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDA 1483 FL EL E+ VE+LT AP QQRK L+ +YLR+ VAEVTR+DA Sbjct: 299 FLEELGREVPESVPLPAPSGQTE----FVERLTLAPAQQRKKLLVDYLRDVVAEVTRIDA 354 Query: 1484 DEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGL- 1542 EIR+EAGFFDLGMDSLMAVELRRR+E VG+++P TL MD+PR++D A YLL +VLGL Sbjct: 355 AEIREEAGFFDLGMDSLMAVELRRRVEHAVGRELPATLAMDYPRVADVALYLLDDVLGLN 414 Query: 1543 ---GEQTNVRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRW 1599 G + + R D+PIA+VAV+CRFP +PDPE +WE+L+GGVDAIRE+P+DR+ Sbjct: 415 AQAGPKADARPVPVPAGPADEPIAIVAVACRFPASPDPEGYWEVLSGGVDAIREIPDDRF 474 Query: 1600 DIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGL 1659 +IDE+YDPDP TPGK Y+R PEFFGISPREAVW++PQQRLMLE WEGL Sbjct: 475 EIDEYYDPDPATPGKIYSRSGGFLDGIDGFDPEFFGISPREAVWMDPQQRLMLEIAWEGL 534 Query: 1660 ERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALG 1719 ERAGY+P+ LRGSR+G+F GVAANEY+HLLS +S++ IE HFITGNALNAI+GRVAFALG Sbjct: 535 ERAGYSPAALRGSRSGIFVGVAANEYSHLLSRDSVESIEAHFITGNALNAIAGRVAFALG 594 Query: 1720 FEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPV 1779 EGPAVAVDTACSS+LVAVHQACQAL SGDCDLALAGGVNVLLSP ++VAASRARMLSP Sbjct: 595 LEGPAVAVDTACSSSLVAVHQACQALHSGDCDLALAGGVNVLLSPESIVAASRARMLSPD 654 Query: 1780 GRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNG 1839 GRCKTFDA+ADGYVRSEGCG+LVLKRLSDA R GDR+CAVI S+VNQDGASSGLTVPNG Sbjct: 655 GRCKTFDAAADGYVRSEGCGILVLKRLSDAQRSGDRICAVIRGSAVNQDGASSGLTVPNG 714 Query: 1840 GAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGS 1899 GAQQRLI A LARAG+ G DVDYLEAHGTGT LGDPIEVQ PLL+GS Sbjct: 715 GAQQRLIAAALARAGVRGGDVDYLEAHGTGTSLGDPIEVQAAAAVYGADRDPRRPLLIGS 774 Query: 1900 VKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT 1959 KTN+GH ESA+G AGLIKVVLSLQH VLP++LHF+NPSPHIPWD+LPVRV+D +PWQ Sbjct: 775 AKTNLGHLESAAGVAGLIKVVLSLQHEVLPRNLHFQNPSPHIPWDSLPVRVVDTAMPWQA 834 Query: 1960 NGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSAR 2019 NGR RRAGVSSFGFTGTNAHVL+EEAPPQ TD +V LSAR Sbjct: 835 NGRPRRAGVSSFGFTGTNAHVLIEEAPPQT--VTYSESVAAEPASAATDVRVEVFPLSAR 892 Query: 2020 SPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXX 2079 SP+ALV LA+RY WL A P DIADVC TAGVGRSHFE+RAALVVDSV Sbjct: 893 SPQALVALAQRYGAWLGAHPEADIADVCFTAGVGRSHFEHRAALVVDSVAGAREVLAELA 952 Query: 2080 XXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLP 2139 GV+RGE P TAWLFTGQGSQYPGMARELFDT+PVFA+TV +CAEA+ MLP Sbjct: 953 ENRLRPGVLRGECADPPKTAWLFTGQGSQYPGMARELFDTEPVFAETVTRCAEAIDGMLP 1012 Query: 2140 RPLLDVLFATDRET----ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQ 2195 RPLL+VLF DR A+ L+HTSFAQPALFAVEMGLARLWQSW IEPDVVLGHSVGQ Sbjct: 1013 RPLLEVLFDIDRGAGGGAAETLRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQ 1072 Query: 2196 YAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAY 2255 YAAACVAGVFSL+DGARLMAERGR+FGSLP+GGRMVAVFA+AE VE A FP VSV AY Sbjct: 1073 YAAACVAGVFSLEDGARLMAERGRLFGSLPDGGRMVAVFAEAEQVEDAAKRFPAVSVAAY 1132 Query: 2256 NGPNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXX 2315 NG NTVLSGPG DL+++V F D+GIRCTWL TSHAFHSELL+PVLD Sbjct: 1133 NGRNTVLSGPGADLDQVVASFSDDGIRCTWLDTSHAFHSELLEPVLDEFEAYAARLQFAT 1192 Query: 2316 PTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLT 2375 PT PLVCNRTGAVLT +TPLDAQYWRRHSRQPVQF ESVRTVAALGCSVLMEIGPQP+LT Sbjct: 1193 PTRPLVCNRTGAVLTAETPLDAQYWRRHSRQPVQFTESVRTVAALGCSVLMEIGPQPILT 1252 Query: 2376 GAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELP 2435 AAVQ WPEH AAPRA+ SLRKG RRQ+A+ALA+AYV GHRP+FAA+HR PRR ++LP Sbjct: 1253 AAAVQAWPEHAAAPRAIVSLRKGACARRQVAEALAAAYVAGHRPEFAALHRAPRRRLDLP 1312 Query: 2436 TYPFQRRRFWPKASSIA-VDG-GTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVI 2493 TYPFQRR FWPK S IA VDG G A SGILGS KDLASGD +YTSRLSVK+QPWL+ HVI Sbjct: 1313 TYPFQRRHFWPKTSGIAGVDGQGAAVSGILGSAKDLASGDVVYTSRLSVKTQPWLSHHVI 1372 Query: 2494 YGTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQ 2553 YGTVVVPGATYAAMALAAVGTPA+++DVFFYEPIIL +K+SREVQLTLHP++ +FQ Sbjct: 1373 YGTVVVPGATYAAMALAAVGTPAQVRDVFFYEPIILADKSSREVQLTLHPSEDRGGWTFQ 1432 Query: 2554 IHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFAD 2613 +HSRPYG R A+WSLNA+G + AG+D AD VD IERL R RPQ LF+TFAD Sbjct: 1433 VHSRPYGVRDAEWSLNADGALVNAGADEPGPADS----VDVAIERLNRTRPQQLFDTFAD 1488 Query: 2614 LELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXX 2673 +ELAWGPTWS SLKSLW+G+GEAVGD++VG ELAE LG+EP+HPVL+DLCTGV Sbjct: 1489 MELAWGPTWSTSLKSLWVGEGEAVGDVVVGDELAEHLGTEPVHPVLLDLCTGVAFPAFPA 1548 Query: 2674 XXXXEQ--GVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGR 2731 + V DLFLPLRYG+V LAE+MPRRFYCRARW +DSETQVF+L+FVD GR Sbjct: 1549 LLAATERGAVPDLFLPLRYGRVALAERMPRRFYCRARWRTGGVDSETQVFDLDFVDRAGR 1608 Query: 2732 ALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPP----SADDAVGTWLIAGF 2787 LGGI EFTVKRAPREALLRGLGGD RLLYTLGWHEVP P + ++A G WL+AGF Sbjct: 1609 HLGGISEFTVKRAPREALLRGLGGDVARLLYTLGWHEVPAPSGDAGADENARGPWLVAGF 1668 Query: 2788 DELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWR-CATPGRKXXXXXXXXXX 2846 DELAA++PGCV + D + ++A R A +G+VWR PG + Sbjct: 1669 DELAAELPGCVQSNGAMDTGDWRRMFARAEERSAPITGIVWRGSGRPGAEESGEEFRARL 1728 Query: 2847 XXXXXITNLLSAVHAAQGPS-VKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTIN 2905 I NLL AVHA V LPGGL I+TE GVA E GE VDPVQ+ALWG GRT I Sbjct: 1729 ETD--IGNLLGAVHALLAEQQVNLPGGLRIITERGVATEPGERVDPVQSALWGLGRTIIA 1786 Query: 2906 EEPALHCRLVDCDGSSEAVDXXXXXXXXPG--IQEPEIAVRQGKLLASRLLPWARSGHLT 2963 E+P L CRL+D DGS EAV P +QEPE+A+RQGK LASRLLPWARSGHL Sbjct: 1787 EQPTLRCRLIDHDGSGEAVRSLASLLAAPDTTLQEPELALRQGKFLASRLLPWARSGHLA 1846 Query: 2964 LPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDP 3023 PR GD+VLAPTERGAIDNLRL ETDVP P G VQ+RVEAAGLNFRDVLNVLGLYPGDP Sbjct: 1847 APRAGDYVLAPTERGAIDNLRLAETDVPPPVAGQVQIRVEAAGLNFRDVLNVLGLYPGDP 1906 Query: 3024 GPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAAT 3083 G IGGDF+G VT++GAGV+G E GQRV+G MQGAFASR NVPAQ LAP+P + AV AA+ Sbjct: 1907 GLIGGDFSGIVTEVGAGVTGFEAGQRVFGFMQGAFASRINVPAQLLAPVPHELSAVAAAS 1966 Query: 3084 IPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLR 3143 IPAAALT RLAFDWAQLKPGD+VLIHAASGGVGLAAIQMAQQ GA VFATAST+KR+TLR Sbjct: 1967 IPAAALTARLAFDWAQLKPGDRVLIHAASGGVGLAAIQMAQQHGAVVFATASTYKRATLR 2026 Query: 3144 RLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKR 3203 RLGV+YVYDSRTTDFADQILADT+GAGVDVVLNSLT+ GFVEAT++ATAQ GRFAEIAKR Sbjct: 2027 RLGVEYVYDSRTTDFADQILADTDGAGVDVVLNSLTNEGFVEATVRATAQNGRFAEIAKR 2086 Query: 3204 DIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPIT 3263 DIW+HE+MA ARPDIAYE+VALD + +P+RIR LL EVSDG+ GEW PLPAEIYP+T Sbjct: 2087 DIWTHERMAAARPDIAYEVVALDGTILQDPERIRGLLAEVSDGLGSGEWAPLPAEIYPLT 2146 Query: 3264 EARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAYLAQLGAGDIV 3323 EA++AFRRMQQARHIGKI DR+YLITGGLGA+GL TA+YLAQLGAGDIV Sbjct: 2147 EAKTAFRRMQQARHIGKIVLQMPNPLQPQADRTYLITGGLGALGLRTASYLAQLGAGDIV 2206 Query: 3324 LTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLA 3383 LT RR+PD AQ+AI +ITER++CRIHT AAD+GDE+QV +LL RIRAELPPLAG+AHLA Sbjct: 2207 LTGRREPDADAQQAISDITERYRCRIHTLAADIGDESQVEELLERIRAELPPLAGVAHLA 2266 Query: 3384 GVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANY 3443 GVLDDALL Q+ +RFRTTL PKA GA H PGQANY Sbjct: 2267 GVLDDALLPQQDVKRFRTTLLPKALGAWHLDRLTRKDDLDFFIVYSSISGVLGSPGQANY 2326 Query: 3444 ATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHA 3503 ATANA+LDGLVA+RRAQGL AT +NFGPW QGGMA+SEAA AN+ AQGL+ ++P+AAL+A Sbjct: 2327 ATANALLDGLVAERRAQGLPATSVNFGPWAQGGMAASEAARANLGAQGLVAMEPTAALNA 2386 Query: 3504 LAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPI 3563 L E++A G+GQA V+KANWQRAAK+LG +RPP+LD +LPSAA +A GDSELLK+L E+P Sbjct: 2387 LGEIVAQGTGQAVVIKANWQRAAKMLGGSRPPMLDHLLPSAAAQAPGDSELLKKLHEVPE 2446 Query: 3564 PQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINA 3623 QRA F+TEFLQ+EVQ FLRLA PAA+SRFLDLGTDSLMA+ELRNRL+ QFGG FTI+A Sbjct: 2447 AQRASFLTEFLQQEVQQFLRLAQAPAATSRFLDLGTDSLMAVELRNRLYGQFGGAFTISA 2506 Query: 3624 TAVFDYPTIGGLAEYLVGQLPD 3645 TAVFDYPTI LAEYL Q+PD Sbjct: 2507 TAVFDYPTISALAEYLAAQVPD 2528 Score = 1091 bits (2822), Expect = 0.0 Identities = 548/962 (56%), Positives = 683/962 (70%), Gaps = 23/962 (2%) Query: 15 AIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAGF 74 AI+ A RFP + E YW +L G +AI ++P DR++I+E++DPDP+TPGK+ +R GF Sbjct: 438 AIVAVACRFPASPDPEGYWEVLSGGVDAIREIPDDRFEIDEYYDPDPATPGKIYSRSGGF 497 Query: 75 VDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLAT 134 +D + GFD FFG+S RE MDPQ R+++E AW +E +G +P +L S +G+FVG+A Sbjct: 498 LDGIDGFDPEFFGISPREAVWMDPQQRLMLEIAWEGLERAGYSPAALRGSRSGIFVGVAA 557 Query: 135 HDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQA 194 ++Y + S + + IEA+ G + A AGR+++ LGL+GPAVAVDTACSSSLVA+HQA Sbjct: 558 NEYSHLLSRD-SVESIEAHFITGNALNAIAGRVAFALGLEGPAVAVDTACSSSLVAVHQA 616 Query: 195 CQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVV 254 CQAL +CDLALAGG NVLL+P +++ S A ML+PDGRCKTFDAAADGYVR EGCG++ Sbjct: 617 CQALHSGDCDLALAGGVNVLLSPESIVAASRARMLSPDGRCKTFDAAADGYVRSEGCGIL 676 Query: 255 VVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVG 314 V+KRL DA R GDRI AVIRGSA+NQDGAS GLTVPNG AQQR+IA AL RAG+R DV Sbjct: 677 VLKRLSDAQRSGDRICAVIRGSAVNQDGASSGLTVPNGGAQQRLIAAALARAGVRGGDVD 736 Query: 315 YLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXXX 374 YLEAHGTGTSLGDPIE QAA V GA R P PLLIGSAKTN+GHLE Sbjct: 737 YLEAHGTGTSLGDPIEVQAAAAVYGADRDPRRPLLIGSAKTNLGHLESAAGVAGLIKVVL 796 Query: 375 XLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAHVI 434 L++E LP++L+F+ PSPHIPW+ LP+ VV +PWQ NG+PR AGVSSFGF GTNAHV+ Sbjct: 797 SLQHEVLPRNLHFQNPSPHIPWDSLPVRVVDTAMPWQANGRPRRAGVSSFGFTGTNAHVL 856 Query: 435 LEEAPAVGTPATTEPVEDPR------RYSVLPLSARTPEALVRLAGEYRDWLRAHPQARL 488 +EEAP + +P R V PLSAR+P+ALV LA Y WL AHP+A + Sbjct: 857 IEEAPPQTVTYSESVAAEPASAATDVRVEVFPLSARSPQALVALAQRYGAWLGAHPEADI 916 Query: 489 ADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFT 548 ADV TAG R+H E RAALVV+S A E+L LA++R PG++RGE + PKTAWLFT Sbjct: 917 ADVCFTAGVGRSHFEHRAALVVDSVAGAREVLAELAENRLRPGVLRGECADPPKTAWLFT 976 Query: 549 GQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADE-LDGDTESPLRH 607 GQGSQYPGMARELFDTEPVFAETV +CAEA+ +L +PLL+V+FD D G LRH Sbjct: 977 GQGSQYPGMARELFDTEPVFAETVTRCAEAIDGMLPRPLLEVLFDIDRGAGGGAAETLRH 1036 Query: 608 TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGR 667 T++AQPALFAVE+GLARLWQSWG EPDVV+GHSVGQY+AACVAGVF +EDGARL+AERGR Sbjct: 1037 TSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGR 1096 Query: 668 LFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVAD 727 LFGSLP GGRM AVF E+ E +P++SVAAYNG NTVLSGP DL+ VA+ D Sbjct: 1097 LFGSLPDGGRMVAVFAEAEQVEDAAKRFPAVSVAAYNGRNTVLSGPGADLDQVVASFSDD 1156 Query: 728 GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAY 787 G+RC WLDTSHAFHS LL+P+LD+FE++A +L++ P R L+ NRTG+ L T LD Y Sbjct: 1157 GIRCTWLDTSHAFHSELLEPVLDEFEAYAARLQFATPTRPLVCNRTGAVLTAETPLDAQY 1216 Query: 788 WRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTT 847 WRRH+RQPV+F +SVRT+A + C VL+EIGP+P+LTA A+ AWP+ A P+ + SLR Sbjct: 1217 WRRHSRQPVQFTESVRTVAALGCSVLMEIGPQPILTAAAVQAWPEHAAAPRAIVSLRKGA 1276 Query: 848 ADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTA 907 RQ+ EA+AAAY AGH P+F A + R+LDLPTYPF+ R FW + D Q A Sbjct: 1277 CARRQVAEALAAAYVAGHRPEFAALHRAPRRRLDLPTYPFQRRHFWPKTSGIAGVDGQGA 1336 Query: 908 SAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDA 967 + + G ++LA+ G+ V L V + H+ T V P A Sbjct: 1337 AVSGIL------------GSAKDLAS---GDVVYTSRLSVKTQPWLSHHVIYGTVVVPGA 1381 Query: 968 RY 969 Y Sbjct: 1382 TY 1383 >tr|D1SGL1|D1SGL1_9ACTO Tax_Id=644283 SubName: Full=KR domain protein;[Micromonospora aurantiaca ATCC 27029] Length = 3741 Score = 1950 bits (5051), Expect = 0.0 Identities = 1375/3733 (36%), Positives = 1855/3733 (49%), Gaps = 189/3733 (5%) Query: 9 EPTPSFAIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGK 66 E + AI+ + R+PG S+ EE W + G +AI D P DR WD++ + DP G Sbjct: 31 EESEPVAIVAMSCRYPGGISSPEELWEFVSSGGDAIGDFPTDRGWDLKRLYHADPDNAGT 90 Query: 67 VVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNT 126 T GF+ D FDA FG+S RE MDPQ R+L+E W E +GIAP SL S + Sbjct: 91 SYTTAGGFLRDAGEFDAALFGISPREAVAMDPQQRLLLEVTWELFERAGIAPLSLRGSRS 150 Query: 127 GVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSS 186 GVFVG + DY + P +E Y+ GT+ + +GR++Y GL+GP+V VDTACSS Sbjct: 151 GVFVGTSGQDYAAVLHRA---PGVEGYVLTGTAASVVSGRLAYTFGLEGPSVTVDTACSS 207 Query: 187 SLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYV 246 + VAIH ACQALR EC LALAGGA VL TP + FS LA DGRCK+F A+ADG Sbjct: 208 ASVAIHLACQALRQRECGLALAGGATVLATPGPFVEFSRQRGLAADGRCKSFAASADGTG 267 Query: 247 RGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRA 306 EG G+++++RL DA R+G + VIR SA+N DGAS GLT PNG +QQRVI AL A Sbjct: 268 WSEGVGMLLLERLSDARRNGHPVLGVIRSSAVNSDGASNGLTAPNGPSQQRVIRQALAGA 327 Query: 307 GLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXX 366 L P V +EAHGTGT+LGDPIEAQA G R PLL+GS K+NIGH + Sbjct: 328 KLTPDLVDVVEAHGTGTTLGDPIEAQALLATYGRERGDAAPLLLGSIKSNIGHTQAAAGI 387 Query: 367 XXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGF 426 + + +P L+ + P+PH+ W + +V E PW +PR A VSSFG Sbjct: 388 AGVIKMVEAMRHGIVPATLHVDEPTPHVDWAAGAVTLVTEATPWPAVDRPRRAAVSSFGM 447 Query: 427 AGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQA 486 +GTN H+ILE+ G A P + + L+ RT AL R A + WL P A Sbjct: 448 SGTNTHLILEQPEPAGAEADRPAAPAP---APVLLTGRTRTALRRQAERWSAWLADDPDA 504 Query: 487 RLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWL 546 R ADV+ T+ +R+ LE RA ++ + R+ + L ALADDRPAPGLV G + E A+L Sbjct: 505 RPADVARTSVLSRSPLEHRAVVLADDRDGLLAALHALADDRPAPGLVTGAAAERGGVAFL 564 Query: 547 FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLR 606 F+GQG+Q G REL++ PVFAE + + + L +PL ++F G E+ L Sbjct: 565 FSGQGAQRAGAGRELYEAYPVFAEALDEVCAHLDHRLPRPLKPLLFAGP---GTAEADLL 621 Query: 607 -HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAER 665 T + Q ALFAVE+ L RL SWG PD+V GHSVG+ +AA VAGV ++D L+A R Sbjct: 622 DQTVFTQAALFAVEVALHRLLGSWGLAPDMVAGHSVGELTAAHVAGVLSLDDACALVAAR 681 Query: 666 GRLFGSLPAGGRMAAVFTAPER-AERLTDEYPSLSVAAYNGANTVL-SGPAKDLESAVAT 723 GRL LP GG M AV R AE + ++VAA NG + V+ SG A ++ Sbjct: 682 GRLMQDLPTGGAMLAVAADEARVAESIAALTDRVAVAAVNGPDAVVVSGEAAAIDELAGL 741 Query: 724 LVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRL 783 GV+ L SHAFHS L++P+L +F + A +L+ R P ++ N TG + Sbjct: 742 WTDRGVQVRRLRVSHAFHSPLMEPMLAEFAAVAARLDLRAPTLPVVSNVTGELADPAQLT 801 Query: 784 DGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATA--LAAWPDPATTPQ--- 838 D YW RH R+ V FA VR L +E+GP VLTA A + TT Sbjct: 802 DPDYWVRHVREAVRFADGVRALRAHGVGTFVEVGPDAVLTAGVQETLAGTETETTDAAPA 861 Query: 839 -VLASLRPTTADHRQITEAVAAAYAAGHLPDFR-AFRQPDARKLDLPTYPFEHRQFWFSD 896 V+ LR D R + A+A + AG P + R +DLPTYPFE + +W Sbjct: 862 VVVPVLRRDRPDRRTLLAALAQLHVAGTPPRWADVLADLPGRLVDLPTYPFERQHYWVPA 921 Query: 897 NRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHN 956 D DT T AG++ AV + + + A+ D T ++LR L + A Sbjct: 922 EAPAD-DTTTGGAGALDRRFWAAVERADLDALRDTLAVTD--TAAAESLRTLLPVLADWR 978 Query: 957 QQRSTHVDPDA-RYEIRWDXXXXXXXXXXXXXDWILV-----GDDTAAVLEFADALTAGG 1010 +QR H D RY W W+L D+ AA A AG Sbjct: 979 RQRQEHSVLDGWRYREEWQVAPEPAPARLTGT-WLLALPAADADNPAARAVRAALTDAGA 1037 Query: 1011 HRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLR 1070 + P DAD A L L A VV + AG+ R L GL Sbjct: 1038 DVRPLTVEP--DADRAALAAAL--AGTEPAGVVSLLAGEP---------RTGGTVLPGLT 1084 Query: 1071 R---LFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGL 1126 L +A DA +P+WLVTR D +V P Q+ +WG GR +E PH WGGL Sbjct: 1085 ATLALAQALGDAGGATPLWLVTRGAVAAASYDRLVDPAQAAIWGLGRVVGVEAPHRWGGL 1144 Query: 1127 ADL-SGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTY 1185 DL S D +A I + GEDQ+A+RG V+A RLVR T Sbjct: 1145 VDLPSDPDDRAVARLAAILTGSTGEDQLAVRGPGVFARRLVRAALGDRTPARRFTPTGTA 1204 Query: 1186 LVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVA 1245 +VTGG G +G A +LA+ GA HVVL SRR P V V D+A Sbjct: 1205 VVTGGTGGLGARAARWLAAAGAEHVVLVSRRGPDAPGAAALEAELTALGTRVTVAACDIA 1264 Query: 1246 DAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEAL 1305 D VA L+ V A PP+ +VH AG TPL+ + AE+ V AGK GA HL++ L Sbjct: 1265 DRAAVADLLDRVEAAGPPVRTVVHTAGVAQATPLAEVTPAELAEVTAGKTAGATHLADLL 1324 Query: 1306 TDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-A 1364 D +LD FV SSIA+ WG GQ Y A NA+LD L R R G + ++ +GPW+ Sbjct: 1325 AD--RELDAFVVYSSIAATWGSGGQAGYAAGNAYLDALVQRRRADGRSGTAIAWGPWSDG 1382 Query: 1365 GMADAESRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRA 1423 GM A++ L +RG+ + PA A A + + V VA +DW+RF P Y A RR Sbjct: 1383 GMHAADAERNLRRRGLPAMDPAVATAALQQALDHDDVTVTVADVDWARFAPAYASARRRP 1442 Query: 1424 FLSEL-ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVD 1482 L + E+ L +L +R+ + +R A+V D Sbjct: 1443 LLEGVPEARAALDGGAAADDGDDGPAATLRRRLAALAPARREETVAEMVRELAADVLGHD 1502 Query: 1483 --ADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVL 1540 A + F DLG DSL AVELR R+ G+ +P TLV DHP + A +LL + Sbjct: 1503 GGAAAVGATTAFRDLGFDSLTAVELRNRLVAATGQALPTTLVFDHPTPAVLARFLLTGLF 1562 Query: 1541 GLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDR- 1598 G G V A+ D+P+AVVA++CR+PG DPE W L+A GVDAI + P DR Sbjct: 1563 GAGAAA-VPDAAPAAVGDDEPVAVVAMACRYPGGVNDPEQLWRLVADGVDAIGDFPTDRG 1621 Query: 1599 WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEG 1658 WD+D YDPDP PG TY P FFGISPREA ++PQQRL+LE WE Sbjct: 1622 WDLDRLYDPDPANPGTTYADKGGFLHAAGEFDPGFFGISPREAAAMDPQQRLLLEVSWEA 1681 Query: 1659 LERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFAL 1718 +ERAG P LRGSRTGVF G +Y LL A ++ E TGNA + +SGRVA+AL Sbjct: 1682 VERAGVEPGVLRGSRTGVFVGTNGQDYGALLMAAG-EQAEGFGATGNAASVVSGRVAYAL 1740 Query: 1719 GFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSP 1778 G EGPAV+VDTACSS+LVA+H A Q+L+ G+CDLALAGGV V+ +P T SR R L+ Sbjct: 1741 GLEGPAVSVDTACSSSLVALHLAVQSLRRGECDLALAGGVTVMATPGTFFEFSRQRGLAA 1800 Query: 1779 VGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPN 1838 GRCK F A ADG EG GVLV++RLSDA R+G V A++ S+VNQDGAS+GLT PN Sbjct: 1801 DGRCKAFAAGADGTGWGEGVGVLVVERLSDARRNGHEVLAIVRGSAVNQDGASNGLTAPN 1860 Query: 1839 GGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMG 1898 G +QQR+I LA A L ADVD +EAHGTGT LGDPIE Q PLL+G Sbjct: 1861 GPSQQRVIRQALAGARLGSADVDVVEAHGTGTTLGDPIEAQALLATYGQGREGHEPLLLG 1920 Query: 1899 SVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQ 1958 S+K+NIGHT++ASG AG+IK+VL+++ GV+P +LH + PSPHI W + V + + PW Sbjct: 1921 SIKSNIGHTQAASGVAGVIKMVLAMREGVVPATLHVDEPSPHIDWTSGAVELATQSRPWP 1980 Query: 1959 TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL-ALS 2017 R RRA VSSFG +GTNAHV++E+A G S V+ +S Sbjct: 1981 AVERARRAAVSSFGMSGTNAHVIIEQA--------DELSVAPVEHGPGLVASDVVVWPVS 2032 Query: 2018 ARSPEALVELARRYDDWLSATPG-------------LDIADVCHTAGVGRSHFEYRAALV 2064 ARS AL A R D+L +D+A V + RS F++RAA V Sbjct: 2033 ARSKGALAGQAARLADFLRGRGAGGAGHLQRANEAVVDVAAVGWSLATTRSAFDHRAA-V 2091 Query: 2065 VDSVXXXXXXXXXXXXXXTPAG--VVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPV 2122 V S TPAG V ++F GQG+Q MA L PV Sbjct: 2092 VGSGTEELLAGLEALSAGTPAGNLVTGAVSGTGAGVVFVFPGQGAQSARMAAGLVGRAPV 2151 Query: 2123 FAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWA 2182 F + C A+A L L+ VL D L+ QP L+AV + LA +WQ Sbjct: 2152 FDARLADCQRALAPYLDVDLVSVLTGEDE---SWLERVEVVQPVLWAVGVALAAVWQHAG 2208 Query: 2183 IEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQ 2242 + P V+GHS G+ AACVAG+ SL+D A+ +A R R L G M +V AE V + Sbjct: 2209 VTPAAVVGHSQGEIGAACVAGILSLEDAAKAVALRSRALTVLRGTGTMASVDLSAEAVAE 2268 Query: 2243 VAGEFPRVSVGAYNGPNT-VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVL 2301 FP V V A NGP+T V+SGP + ++VE + +G+R + +A HS + V Sbjct: 2269 RLPAFPGVGVAAVNGPSTVVVSGPPRPVADLVESCQADGVRARLIPVDYASHSVAVQDVA 2328 Query: 2302 DXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALG 2361 + LV TG + A YW + RQ VQF +VR A G Sbjct: 2329 EQLRADLAGVSPQAGHTRLVSTLTGD-WVDPFSMSADYWYDNLRQTVQFDAAVRVAVAAG 2387 Query: 2362 CSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF 2421 + +EI P PVL + + + + SLR+G D ++ LA+A+ G D Sbjct: 2388 HTTFVEISPHPVLAMPVTAILDDVGVSGHVLGSLRRGDDDATRLLTNLATAHTIGLPVDL 2447 Query: 2422 AAVHRQPRRPVELPTYPFQRRRFWPKASSIAV-DGGTAASGILGSGKDLASG-------- 2472 AV + V LPTY F+ R+W A + V D G+A G+ G L S Sbjct: 2448 TAVLAE-TGTVALPTYAFEHGRYWLDAPAHRVRDVGSA--GLQDIGHPLLSAAVPVADDR 2504 Query: 2473 DTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVG--TPARLKDVFFYEPIILP 2530 + T RLSV++ PWLADH + G V+VPG M + A ++ D+ P++LP Sbjct: 2505 TVVLTGRLSVRTHPWLADHAVGGAVIVPGTGVIDMVVRAGDEVDAGQVGDLTLINPLVLP 2564 Query: 2531 EKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSD 2590 + +VQ+ + P S +HSRP + A+W+ +AEG + DP AA Q Sbjct: 2565 ATGAMQVQVRVGPPADTGERSVTVHSRPEEDADAEWTRHAEGLLLPQLPDP-AAVPGQWP 2623 Query: 2591 PVD--EVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAE 2648 P E+ L+ Q A+ L +GP + G L+ +W GDGE ++ + E + Sbjct: 2624 PAGAVEIDADLDAWYAQ-----MAEGGLGYGPAFRG-LRRVWRGDGEVYAEVALPEEASA 2677 Query: 2649 QLGSEPMHPVLMDL---CTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYC 2705 +HP L D +GV G ++P + V L R Sbjct: 2678 DASRFGLHPALFDAALQASGVTALLGDPADTSGAG----WMPFAFRSVALHAHGATRLRA 2733 Query: 2706 RARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLG 2765 R R +L +T L D G+ + + T + + G +A L T Sbjct: 2734 RLR----SLGPDTVAVTL--ADTAGQPVATVESLTFR-----PVAAGRADEAAALRRTSV 2782 Query: 2766 WH-EVPPPPSADDAVG---TWLIAGFDEL---AAKVPGCVPIDRNTDLQVLGEVLSQAHA 2818 +H + P P AD A G +W + G D L A P+ + DL L Sbjct: 2783 FHLDWTPLPGADAAAGQTVSWALLGDDTLGLTGALTAAGHPVRSHADLAAL--------V 2834 Query: 2819 RGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXIT-NLLSAVHAAQGPSVKLPGGLWIVT 2877 G SG V R + L+ V G S L + T Sbjct: 2835 AEIGESGDVPDTVLDLRSGAEPDPQRAGEAAHDAARDALALVQQWLGESRLERSRLVLHT 2894 Query: 2878 EHGVACESGE-PVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGI 2936 V GE P D +A+LWG R+ +E P L+D D +A Sbjct: 2895 RGAVGAAPGEAPRDLARASLWGLVRSAQSEHPG-RFTLLDTD---DAAASLAAVPAAVAS 2950 Query: 2937 QEPEIAVRQGKLLASRLLPWARSGHLTLPRGG-DFVLAPTERGAIDNLRLTETDVPEPD- 2994 EP++A+R G L RL +G L LP G + L TE+G ++NL L +P P+ Sbjct: 2951 GEPQLALRDGAPLVPRLARARDAGVLPLPAGEVPWRLDVTEKGTLENLAL----LPGPET 3006 Query: 2995 -----EGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQR 3049 G+V V + A+GLNFRDV+ LG+ P D +G + AG V +G GV+ L G R Sbjct: 3007 AGELPAGHVLVGMRASGLNFRDVVLALGMVP-DQEVLGNEGAGVVLGVGPGVTDLAPGDR 3065 Query: 3050 VYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLI 3108 V G G+F+S + L IPDG +AA +P LT + A+L+ G+ VL+ Sbjct: 3066 VAGIFSGSFSSAAVTDRRLLTRIPDGWSYTDAAAVPVVFLTAWYGLVELARLRAGESVLV 3125 Query: 3109 HAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGV--KYVYDSRTTDFADQILADT 3166 HAA+GGVG+AA+Q+A+ GAE++ TAS K LR G ++ SR+ DFAD+ T Sbjct: 3126 HAAAGGVGMAAVQIARHLGAEIYGTASPGKWPALRATGFDDAHLASSRSLDFADEFAHRT 3185 Query: 3167 NGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALD 3226 GVDVVLN+L +V+A+L+ A GGRF E+ K D +Q+A P ++Y++ L Sbjct: 3186 GSRGVDVVLNALRGE-YVDASLRLLADGGRFVEMGKTDKRDPQQVAADHPGVSYQVFDL- 3243 Query: 3227 TVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXX 3286 + P +I +L E+ A G PLP + + A AFR + QARH+GK+ Sbjct: 3244 --IEAGPGKIGAMLGELMALFAAGALRPLPRRTWDVRRAPEAFRFLSQARHVGKL--ALS 3299 Query: 3287 XXXXXXXDRSYLITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERH 3345 D + L++G G +G +L GA ++L SRR PD + + Sbjct: 3300 IPQTPRLDGTVLVSGATGTLGALLCRHLVTAHGARQLLLVSRRGPDAEGADDLLADLKAL 3359 Query: 3346 KCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAP 3405 + AAD+ D VAD+L+ + PL + H AGVLDDA + + P+R L P Sbjct: 3360 GADVSIVAADLADPDAVADVLSTVDRR-HPLRAVVHAAGVLDDATVESLTPDRLAAVLRP 3418 Query: 3406 KAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVAT 3465 K A + PGQ NYA NA LD L RRA GL A Sbjct: 3419 KVDVAWNLHRATLGHELSAFVLFSAAAGVFGGPGQGNYAAGNAFLDALAEHRRALGLPAV 3478 Query: 3466 GINFGPWGQGGMASSEAATANI---TAQGLIPLDPSAALHALAEVIANGSGQATVLKANW 3522 + +G W Q + +A+I G+ L + L AL + + S +AT++ A Sbjct: 3479 ALAWGRWAQASGMTGHLDSADIRRLDRGGMAALSDAEGL-ALFDAVWR-SERATLMPAKI 3536 Query: 3523 QRAAKVLGSARPPILDLVL-----PSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQRE 3577 GS P+L ++ +AAG AT + L +P +RA + + + Sbjct: 3537 VTGVAAPGSPVHPLLTNLVRAAGRRAAAGAATDGQAYAETLRALPDDKRARALRDLVLSH 3596 Query: 3578 VQNFLRLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGL 3635 V L P + F +LG DSL A+ELRNRL + G + AT VFD PT L Sbjct: 3597 VAVVLGHGDPAGIEPTRAFRELGFDSLTAVELRNRLGAATG--LRLPATLVFDNPTPEAL 3654 Query: 3636 AEYLVGQLPDAEA 3648 A +L GQ A + Sbjct: 3655 AAHLGGQFVPANS 3667 Score = 704 bits (1818), Expect = 0.0 Identities = 410/940 (43%), Positives = 539/940 (57%), Gaps = 26/940 (2%) Query: 1536 LVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREV 1594 L V+ +QT R VTA +P+A+VA+SCR+PG PE WE ++ G DAI + Sbjct: 11 LTRVVAELQQTRQRLRE-VTAEESEPVAIVAMSCRYPGGISSPEELWEFVSSGGDAIGDF 69 Query: 1595 PEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLE 1653 P DR WD+ Y DPD G +YT FGISPREAV ++PQQRL+LE Sbjct: 70 PTDRGWDLKRLYHADPDNAGTSYTTAGGFLRDAGEFDAALFGISPREAVAMDPQQRLLLE 129 Query: 1654 TVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGR 1713 WE ERAG AP LRGSR+GVF G + +YA +L +E + +TG A + +SGR Sbjct: 130 VTWELFERAGIAPLSLRGSRSGVFVGTSGQDYAAVL--HRAPGVEGYVLTGTAASVVSGR 187 Query: 1714 VAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRA 1773 +A+ G EGP+V VDTACSSA VA+H ACQAL+ +C LALAGG VL +P V SR Sbjct: 188 LAYTFGLEGPSVTVDTACSSASVAIHLACQALRQRECGLALAGGATVLATPGPFVEFSRQ 247 Query: 1774 RMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSG 1833 R L+ GRCK+F ASADG SEG G+L+L+RLSDA R+G V VI +S+VN DGAS+G Sbjct: 248 RGLAADGRCKSFAASADGTGWSEGVGMLLLERLSDARRNGHPVLGVIRSSAVNSDGASNG 307 Query: 1834 LTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXX 1893 LT PNG +QQR+I LA A L+ VD +EAHGTGT LGDPIE Q Sbjct: 308 LTAPNGPSQQRVIRQALAGAKLTPDLVDVVEAHGTGTTLGDPIEAQALLATYGRERGDAA 367 Query: 1894 PLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDE 1953 PLL+GS+K+NIGHT++A+G AG+IK+V +++HG++P +LH + P+PH+ W A V ++ E Sbjct: 368 PLLLGSIKSNIGHTQAAAGIAGVIKMVEAMRHGIVPATLHVDEPTPHVDWAAGAVTLVTE 427 Query: 1954 PVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV 2013 PW R RRA VSSFG +GTN H+++E+ P +P Sbjct: 428 ATPWPAVDRPRRAAVSSFGMSGTNTHLILEQPEP-----------AGAEADRPAAPAPAP 476 Query: 2014 LALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXX 2073 + L+ R+ AL A R+ WL+ P ADV T+ + RS E+RA ++ D Sbjct: 477 VLLTGRTRTALRRQAERWSAWLADDPDARPADVARTSVLSRSPLEHRAVVLADDRDGLLA 536 Query: 2074 XXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEA 2133 G+V G R A+LF+GQG+Q G REL++ PVFA+ + + Sbjct: 537 ALHALADDRPAPGLVTGAAAERGGVAFLFSGQGAQRAGAGRELYEAYPVFAEALDEVCAH 596 Query: 2134 VADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHS 2192 + LPRPL +LFA ADLL T F Q ALFAVE+ L RL SW + PD+V GHS Sbjct: 597 LDHRLPRPLKPLLFAGPGTAEADLLDQTVFTQAALFAVEVALHRLLGSWGLAPDMVAGHS 656 Query: 2193 VGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHV-EQVAGEFPRVS 2251 VG+ AA VAGV SLDD L+A RGR+ LP GG M+AV AD V E +A RV+ Sbjct: 657 VGELTAAHVAGVLSLDDACALVAARGRLMQDLPTGGAMLAVAADEARVAESIAALTDRVA 716 Query: 2252 VGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXX 2310 V A NGP+ V+SG ++E+ + D G++ L SHAFHS L++P+L Sbjct: 717 VAAVNGPDAVVVSGEAAAIDELAGLWTDRGVQVRRLRVSHAFHSPLMEPMLAEFAAVAAR 776 Query: 2311 XXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGP 2370 PTLP+V N TG + D YW RH R+ V+FA+ VR + A G +E+GP Sbjct: 777 LDLRAPTLPVVSNVTGELADPAQLTDPDYWVRHVREAVRFADGVRALRAHGVGTFVEVGP 836 Query: 2371 QPVLTG------AAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAV 2424 VLT A + A V LR+ DRR + ALA +V G P +A V Sbjct: 837 DAVLTAGVQETLAGTETETTDAAPAVVVPVLRRDRPDRRTLLAALAQLHVAGTPPRWADV 896 Query: 2425 HRQ-PRRPVELPTYPFQRRRFWPKASSIAVDGGTAASGIL 2463 P R V+LPTYPF+R+ +W A + A D T +G L Sbjct: 897 LADLPGRLVDLPTYPFERQHYWVPAEAPADDTTTGGAGAL 936 >tr|Q53840|Q53840_SORCE Tax_Id=56 (sorB)SubName: Full=Soraphen polyketide synthase B;[Sorangium cellulosum] Length = 8817 Score = 1908 bits (4942), Expect = 0.0 Identities = 1354/3715 (36%), Positives = 1855/3715 (49%), Gaps = 185/3715 (4%) Query: 15 AIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + RFPG + E+ W LL DG++AISD+P +R W ++ G+ R Sbjct: 37 AIVAMSCRFPGDVRTPEDLWKLLLDGKDAISDLPPNRGWKLDAL-----DVHGRSPVREG 91 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF D FD FFG+S RE +DPQ R+L+E +W A E +GI P SL S +GVFVG+ Sbjct: 92 GFFYDADAFDPAFFGISPREALAIDPQQRLLLEISWEAFERAGIDPASLQGSQSGVFVGV 151 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 +DY + E E + ++A G++ + A+GRI+Y G QGPA++VDTACSSSLVA+H Sbjct: 152 IHNDYDALL--ENAAGEHKGFVATGSTASVASGRIAYTFGFQGPAISVDTACSSSLVAVH 209 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 ACQALR EC LALAGG V+ TPA + F + APDGRCK+F A+G EG G Sbjct: 210 LACQALRRGECSLALAGGVTVMATPAVFVAFDSESAGAPDGRCKSFSVEANGSGWAEGAG 269 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++++RL DAV++G + AV+RGSA+NQDG S GLT PNG AQ+RVI AL A L P D Sbjct: 270 MLLLERLSDAVQNGHPVLAVLRGSAVNQDGRSQGLTAPNGPAQERVIRQALDSARLTPKD 329 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT+LGDPIEAQA G + + PL +GS K+N+GH + Sbjct: 330 VDVVEAHGTGTTLGDPIEAQAILATYGEAHSQDRPLWLGSLKSNLGHAQAAAGVGSVIKM 389 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 L+ LPK L+ + PSPHI W ++++ E V W NG PR AGVS+FG +GTNAH Sbjct: 390 VLALQQGLLPKTLHAQNPSPHIDWSPGTVKLLNEPVVWTTNGHPRHAGVSAFGISGTNAH 449 Query: 433 VILEEAPAVG--TPATTEPVED--PRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARL 488 VILEEAPA+ PA ++P + P + VL LSA++ A+ A RD L A + L Sbjct: 450 VILEEAPAIARVEPAASQPASEPLPAAWPVL-LSAKSEAAVRAQAKRLRDHLLAKSELAL 508 Query: 489 ADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFT 548 ADV+++ T RAH EQRAAL+V R+ + L ALA A V G S K A LFT Sbjct: 509 ADVAYSLATTRAHFEQRAALLVKGRDELLSALDALAQGHSA--AVLGRSGAPGKLAVLFT 566 Query: 549 GQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHT 608 GQGSQ P M R L+D PVF + + + L++PL DV+F D + + L T Sbjct: 567 GQGSQRPTMGRGLYDVFPVFRDALDTVGAHLDRELDRPLRDVLFAPD--GSEQAARLEQT 624 Query: 609 TYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRL 668 + QPALFA+E+ L +L QS+G +P +++GHS+G+ AA VAGV ++DG L+A R +L Sbjct: 625 AFTQPALFALEVALFQLLQSFGLKPALLLGHSIGELVAAHVAGVLSLQDGCTLVAARAKL 684 Query: 669 FGSLPAGGRMAAVFTAPERAERLTDEYPS-LSVAAYNG-ANTVLSGPAKDLESAVATLVA 726 +LP GG M + + E L Y S+AA NG +TV++G + A Sbjct: 685 MQALPQGGAMVTLRASEEEVRDLLQPYEGRASLAALNGPLSTVVAGDEDAVVEIARQAEA 744 Query: 727 DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGA 786 G + L SHAFHS +D +LDDF AQ L Y + +I N TG+ Sbjct: 745 LGRKTTRLRVSHAFHSPHMDGMLDDFRRVAQSLTYHPARIPIISNVTGARATDHELASPD 804 Query: 787 YWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATAL-AAWPDPATTP-QVLASLR 844 YW RH R V F VR L RV LE+GP VL+A A A D T+P L +LR Sbjct: 805 YWVRHVRHTVRFLDGVRALHAEGARVFLELGPHAVLSALAQDALGQDEGTSPCAFLPTLR 864 Query: 845 PTTADHRQITEAVAAAYAAGHLPDFRAFRQPDA-RKLDLPTYPFEHRQFWFSDNRAIDRD 903 D T A+ A ++AG PD+ AF P A RK+ LPTY F+ +FW ++A Sbjct: 865 KGRDDAEAFTAALGALHSAGITPDWSAFFAPFAPRKVSLPTYAFQRERFWPDASKA---- 920 Query: 904 TQTASAGSVTPHRTQAVRLLEDGQIEELAAL--IDGETVDEQTLRVLNKLAA-RHNQQRS 960 A + P + +E G ++ L+ +DG+ +L L++ RH +Q Sbjct: 921 -PGADVSHLAPLEGGLWQAIERGDLDALSGQLHVDGDERRAALALLLPTLSSFRHERQEQ 979 Query: 961 THVDPDARYEIRWDXXXXXXXXXXXXXDWILVG----DDTAAVLEFADALTAGGHRHQIV 1016 + VD RY I W W++V DD A +ALT G R + Sbjct: 980 STVDA-WRYRITWKPLTTAETPADLAGTWLVVVPAALDDDALPSALTEALTRRGARVLAL 1038 Query: 1017 ALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMR---DLLRVQHRTL------- 1066 L + D L + LR A A AP+R LL + R L Sbjct: 1039 RLSQAHLDREALAEHLRQACA-------------ETAPIRGVLSLLALDERPLADRPALP 1085 Query: 1067 GGLR---RLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHI 1122 GL L +A D +L +P+W TR + +D + P Q+ WG GR LE P Sbjct: 1086 AGLALSLSLAQALGDLDLEAPLWFFTRGAVSIGHSDPLAHPAQAMTWGLGRVIGLEHPDR 1145 Query: 1123 WGGLADL-SGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVRE 1181 WGGL D+ +G D + + R EDQ+ALR +YA R+VR P P R+ Sbjct: 1146 WGGLVDVCAGVDESAVGRLLPALAERHDEDQLALRPAGLYARRIVR---APLGDAPPARD 1202 Query: 1182 ---DRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVR 1238 T L+TGG GAIG VA +LA GA H+VL SRR Sbjct: 1203 FTPGGTILITGGTGAIGAHVARWLARRGAQHLVLISRRGAEAPGASELHDELSALGARTT 1262 Query: 1239 VITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGA 1298 + DVAD + VA L+ + AE + + HA+G PL ++ V +GKV GA Sbjct: 1263 LAACDVADRNAVATLLEQLDAEGSQVRAVFHASGIEHHAPLDATSFRDLAEVVSGKVEGA 1322 Query: 1299 WHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVN 1358 HL + L LD FV SS A+VWGG Q Y AANAFLD LA R G+TA SV Sbjct: 1323 KHLHDLLGS--RPLDAFVLFSSGAAVWGGGQQGGYAAANAFLDALAEHRRSAGLTATSVA 1380 Query: 1359 FGPW-AAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLY 1416 +G W GMA ++ A L+QRG+ ++P+ ALA +A + V VA IDW+RF P + Sbjct: 1381 WGAWGGGGMATDQAAAHLQQRGLSRMAPSLALAALALALEHDETTVTVADIDWARFAPSF 1440 Query: 1417 QQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVA 1476 A R L +L L+++L ++ L+ + +R+ A Sbjct: 1441 SAARPRPLLRDLPEAQRALETSEGASSEHGPAPDLLDKLRSRSESEQLRLLVSLVRHETA 1500 Query: 1477 EVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYL 1535 V A + + GF DLG+DSLMAVELRRR++Q G +P TL DHP A +L Sbjct: 1501 LVLGHEGASHVDPDKGFLDLGLDSLMAVELRRRLQQATGIKLPATLAFDHPSPHRVALFL 1560 Query: 1536 ---LVEVLG--LGEQTNVRQASTVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVD 1589 L LG L + + + A +D+PIA+V ++ R P G D ++ WE LA G D Sbjct: 1561 RDSLAHALGTRLSVEPDAAALPALRAASDEPIAIVGMALRLPGGVGDVDALWEFLAQGRD 1620 Query: 1590 AIREVPEDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQR 1649 + +P+ RWD YDPDPD K+Y R P FFGISPREA ++PQ R Sbjct: 1621 GVEPIPKARWDAAALYDPDPDAKTKSYVRHAAMLDQVDLFDPAFFGISPREAKHLDPQHR 1680 Query: 1650 LMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNA 1709 L+LE+ W+ LE AG P L+ S TGVF G+ A+EYA L S + + + + G A + Sbjct: 1681 LLLESAWQALEDAGIVPPTLKDSPTGVFVGIGASEYA--LREASTEDSDAYALQGTAGSF 1738 Query: 1710 ISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVA 1769 +GR+A+ LG +GPA++VDTACSS+LVA+H ACQAL+ G+C+LALA GV+V+ SP V Sbjct: 1739 AAGRLAYTLGLQGPALSVDTACSSSLVALHLACQALRQGECNLALAAGVSVMASPEGFVL 1798 Query: 1770 ASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDG 1829 SR R L+P GR KTF A+ADGY R EG VL L+RL DA+ G RV A++ +++N DG Sbjct: 1799 LSRLRALAPDGRSKTFSANADGYGRGEGVIVLALERLGDALARGHRVLALVRGTAINHDG 1858 Query: 1830 ASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXX 1889 ASSG+T PNG +QQ+++ A L A ++ ADVD +E HGTGT LGDPIEVQ Sbjct: 1859 ASSGITAPNGTSQQKVLRAALHDARITPADVDVVECHGTGTSLGDPIEVQALAAVYADGR 1918 Query: 1890 XXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVR 1949 PLL+G++KTNIGH E+ASG AG+ K+V SL+H LP +LH +P I WD L + Sbjct: 1919 PAEKPLLLGALKTNIGHLEAASGLAGVAKIVASLRHDALPPTLHTGPRNPLIDWDTLAID 1978 Query: 1950 VIDEPVPW--QTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGT 2007 V+D P W + RRAGVS+FG +GTNAHV++EEAP L Sbjct: 1979 VVDTPRSWARHEDSSPRRAGVSAFGLSGTNAHVILEEAPAALSGEPATSQTASRPLPAAC 2038 Query: 2008 DDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDS 2067 + LSARS A+ A+R D L A L + DV ++ R+HFE+RAAL+ Sbjct: 2039 -----AVLLSARSEAAVRAQAKRLRDHLLAHDDLALIDVAYSQATTRAHFEHRAALLARD 2093 Query: 2068 VXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTV 2127 V G ++F GQGSQ+ GMA L D+ PVF + Sbjct: 2094 RDELLSALDSLAQDKPAPSTVLGRSGSHGKVVFVFPGQGSQWEGMALSLLDSSPVFRAQL 2153 Query: 2128 RQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDV 2187 C A+A + LL VL E A L QPALFAV + LA LW+S +EP Sbjct: 2154 EACERALAPHVEWSLLAVL--RRDEGAPSLDRVDVVQPALFAVMVSLAALWRSLGVEPAA 2211 Query: 2188 VLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF 2247 V+GHS G+ AAA VAG SL+D AR+ A R + ++ G M AV A ++ + Sbjct: 2212 VVGHSQGEIAAAFVAGALSLEDAARIAALRRKALTTVGGNGGMAAVELGASDLQTYLAPW 2271 Query: 2248 -PRVSVGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXX 2305 R+S A N P T++SG ++ +++ + + +A HS +D V D Sbjct: 2272 GDRLSTAAVNSPRATLVSGEPAAVDALLDVLTATKVFARKIRVDYASHSAQMDAVQDELA 2331 Query: 2306 XXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVL 2365 LPL TG L G + LD YW R+ RQ V F+ + + G Sbjct: 2332 AGLANIAPRTCELPLYSTVTGTRLDG-SELDGAYWYRNLRQTVLFSSATERLLDDGHRFS 2390 Query: 2366 MEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGG---HRPDFA 2422 +E+ P PVLT A + P V S+R+ ++ + A G DF Sbjct: 2391 VEVSPHPVLTLALRETCERSPLDPVVVGSIRREEGHLARLLLSWAELSTRGLALDWKDFF 2450 Query: 2423 AVHRQPRRPVELPTYPFQRRRFWPKASS--------IAVDGGTAASGILGSGKDLAS-GD 2473 A + R V LPTYPFQR RFW S+ D G +LG+ A G Sbjct: 2451 APYAP--RKVSLPTYPFQRERFWLDVSTDERFRRRLRRPDLGRPIP-LLGAAVAFADRGG 2507 Query: 2474 TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILP 2530 ++T RLS+ PWL H ++GT ++PG + +AL VG ++++ P+ LP Sbjct: 2508 FLFTGRLSLAEHPWLEGHAVFGTPILPGTGFLELALHVAHRVGLDT-VEELTLEAPLALP 2566 Query: 2531 EKASREVQLTLHPADGGSVLSFQIHSRPYGE-RGADWSLNAEGTVDTAGSDPDAAADEQS 2589 + + +Q+++ P D + HSR + W+ +A G++ A P +AD Sbjct: 2567 SQDTVLLQISVGPVDDAGRRALSFHSRQEDALQDGPWTRHASGSLSPA--TPSLSADLHE 2624 Query: 2590 DPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQ 2649 P I + + L+ T A+L LA+GP + G L+S++ E + + + Sbjct: 2625 WPPSSAIP----VDLEGLYATLANLGLAYGPEFQG-LRSVYKRGDELFAEAKLPEAAEKD 2679 Query: 2650 LGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARW 2709 +HP L+D ++ + LP + V+L + R R+ Sbjct: 2680 AARFALHPALLD-------SALHALAFEDEQRGTVALPFSWSGVSL--RSVGATTLRVRF 2730 Query: 2710 HRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEV 2769 HR +S + D G L ++ + R A LR L+ + W E+ Sbjct: 2731 HRPKGESSVSIV---LADAAGDPLASVQALAM-RTTSAAQLRTPAASHHDALFRVDWSEL 2786 Query: 2770 PPPPSADDA-VGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVW 2828 P S A G L G +LA P+ R DL L L Q GA G+V Sbjct: 2787 QSPTSPPAAPSGVLLGTGGHDLALD----APLARYADLAALRSALDQ----GASPPGLV- 2837 Query: 2829 RCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGG-LWIVTEHGVACESGE 2887 P T L A+ A +L L +VT VA + + Sbjct: 2838 --VAP---FIDRPAGDLVPSAHEATALALALLQAWLADERLASSRLVLVTRRAVATHTED 2892 Query: 2888 PV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQG 2946 V D A LWG R+ +E P L LVD D SEA G E ++A+R G Sbjct: 2893 DVKDLAHAPLWGLARSAQSEHPDLPLFLVDID-LSEASQQALLGALDTG--ERQLALRNG 2949 Query: 2947 KLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPD----EGYVQVRV 3002 K L RL + L P+ + L +G D L L D PE G V++ V Sbjct: 2950 KPLIPRLAQPRSTDALIPPQAPTWRLHIPTKGTFDALAL--VDAPEAQAPLAHGQVRIAV 3007 Query: 3003 EAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRF 3062 AAGLNFRDV++ LG+YPGD P+GG+ AG VT++G GVS +G RV G AF Sbjct: 3008 HAAGLNFRDVVDTLGMYPGDAPPLGGEGAGIVTEVGPGVSRYTVGDRVMGVFGAAFGPTA 3067 Query: 3063 NVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGVGLAAIQ 3121 A+ + PIP +AA++P LT D LKP +VLIHAA+GGVG AA+Q Sbjct: 3068 IADARMICPIPHAWSFAQAASVPIIYLTAYYGLVDLGHLKPNQRVLIHAAAGGVGTAAVQ 3127 Query: 3122 MAQQSGAEVFATASTFKRSTLRRLGV--KYVYDSRTTDFADQILADTNGAGVDVVLNSLT 3179 +A+ GAEVFATAS K S LR LG ++ SR F L T+G G+DVVL+ L Sbjct: 3128 LARHLGAEVFATASPGKWSALRALGFDDAHLASSRDLGFEQHFLRSTHGRGMDVVLDCL- 3186 Query: 3180 SAGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDL 3239 + FV+A+L+ GGRF E+ K DI + + A P + Y A D V PDRI + Sbjct: 3187 AREFVDASLRLMPSGGRFIEMGKTDIREPDAIGLAYPGVVYR--AFD-VTEAGPDRIGQM 3243 Query: 3240 LTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLI 3299 L E+ RG P + I A AFR + QARH+GK + + LI Sbjct: 3244 LAELLSLFERGVLRLPPITSWDIRHAPQAFRALAQARHVGKF--VLTIPRPIDPEGTVLI 3301 Query: 3300 TGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGD 3358 TGG G +G+ A +L A+ A ++LTSR+ A+ E + A DV D Sbjct: 3302 TGGTGTLGVLVARHLVAKHSAKHLLLTSRKGARAPGAEALRSELEALGASVTLVACDVAD 3361 Query: 3359 EAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXX 3418 + LL I + P+ + H AG LDD L + + ER PK A + Sbjct: 3362 PRALRTLLDSIPRD-HPITAVVHAAGALDDGPLGSMSAERIARVFDPKLDAAWYLHELTQ 3420 Query: 3419 XXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ-GGM 3477 PGQ+NYA ANA LD L RRAQGL A + +G W + GM Sbjct: 3421 DEPVAAFVLFSAASGVLGGPGQSNYAAANAFLDALAHHRRAQGLPAASLAWGYWAERSGM 3480 Query: 3478 AS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP 3535 S A A + G+ PLD AL +L +V A V PP Sbjct: 3481 TRHLSAADAARMRRAGVRPLDTDEAL-SLFDVALLRPEPALVPAPFDYNVLSTSADGVPP 3539 Query: 3536 ILDLVLPS-----AAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAA 3590 + ++ + AA S L + L +P +R + + ++ E + L LAS + Sbjct: 3540 LFQRLVRARIARKAASNTALASSLAEHLSSLPPAERERVLLDLVRTEAASVLGLASFESL 3599 Query: 3591 SSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 +LG DSLMA+ELRNRL + G + AT +FDYPT L+ + L Sbjct: 3600 DPHRPLQELGLDSLMALELRNRLAAAAG--LRLQATLLFDYPTPTALSRFFTTHL 3652 Score = 1536 bits (3976), Expect = 0.0 Identities = 1010/2662 (37%), Positives = 1372/2662 (51%), Gaps = 87/2662 (3%) Query: 15 AIIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAG 73 AI+G A R PG + W L GR+A+ +P RWD +DPDP K R A Sbjct: 5225 AIVGMALRLPGGIGDVDALWEFLAQGRDAVEPIPHARWDAGALYDPDPDAKAKSYVRHAA 5284 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 +D V FD FFG+S RE + +DPQHR+L+E+AW A+E +GI P++L +S TGVFVG+ Sbjct: 5285 MLDQVDLFDPAFFGISPREAKYLDPQHRLLLESAWLALEDAGIVPSTLKDSPTGVFVGIG 5344 Query: 134 THDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQ 193 +Y A + E+EAY GT+ + AAGR++Y LGLQGPA++VDTACSSSLVA+H Sbjct: 5345 ASEY---ALRNTSSEEVEAYALQGTAGSFAAGRLAYTLGLQGPALSVDTACSSSLVALHL 5401 Query: 194 ACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGV 253 ACQALR EC+LALA G +V+ +P + S LAPDGR KTF ADGY RGEG V Sbjct: 5402 ACQALRQGECNLALAAGVSVMASPGLFVVLSRMRALAPDGRSKTFSTNADGYGRGEGVVV 5461 Query: 254 VVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADV 313 + ++RL DA+ G R+ A++RG+A+N DGAS G+T PNG + Q+V+ AL A + PADV Sbjct: 5462 LALERLGDALARGHRVLALVRGTAMNHDGASSGITAPNGTSHQKVLRAALHDAHIGPADV 5521 Query: 314 GYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXX 373 +E HGTGTSLGDPIE QA V GR E+PLL+G+ KTNIGHLE Sbjct: 5522 DVVECHGTGTSLGDPIEVQALAAVYADGRPAEKPLLLGALKTNIGHLEAASGLAGVAKIV 5581 Query: 374 XXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRN--GKPRIAGVSSFGFAGTNA 431 L ++ LP L+ +P I W+ L I+VV T W R+ G PR AGVS+FG +GTNA Sbjct: 5582 ASLRHDALPPTLHTTPRNPLIEWDALAIDVVDATRAWARHEDGSPRRAGVSAFGLSGTNA 5641 Query: 432 HVILEEAPAVG----TPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQAR 487 HVILEEAPA+ T A P + VL LSAR+ A+ A RD L AH Sbjct: 5642 HVILEEAPAIPQAEPTAAQLASQPLPAAWPVL-LSARSEPAVRAQAQRLRDHLLAHDDLA 5700 Query: 488 LADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLF 547 LADV+++ T RA E RAALVV+ RE + L +LA RPAP V S K ++F Sbjct: 5701 LADVAYSLATTRATFEHRAALVVHDREELLSALDSLAQGRPAPSTVVERSGSHGKVVFVF 5760 Query: 548 TGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRH 607 GQGSQ+ GMA L DT PVF + C A+A ++ LL V+ + PL Sbjct: 5761 PGQGSQWEGMALSLLDTSPVFRAQLEACERALAPHVDWSLLAVLRGEEGAP-----PLDR 5815 Query: 608 TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGR 667 QPALF++ + LA LW+S G EPD VVGHS G+ +AACVAG +ED A+L+A R R Sbjct: 5816 VDVVQPALFSMMVSLAALWRSMGVEPDAVVGHSQGEIAAACVAGALSLEDAAKLVALRSR 5875 Query: 668 LFGSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGAN-TVLSGPAKDLESAVATLV 725 L G MAAV E A RL LS+ A N T +SG + + + L Sbjct: 5876 ALVELAGQGAMAAVELPEAEVARRLQRYGDRLSIGAINSPRFTTISGEPPAVAALLRDLE 5935 Query: 726 ADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDG 785 ++GV L A HSA ++ I D+ LE R +G+A+ S LD Sbjct: 5936 SEGVFALKLSYDFASHSAQVESIRDELLDLLSWLEPRSTAVPFYSTVSGAAIDGS-ELDA 5994 Query: 786 AYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRP 845 AYW R+ RQPV FA +V+ L R +E+ P PVLT + V+ SL Sbjct: 5995 AYWYRNLRQPVRFADAVQGLLAGEHRFFVEVSPSPVLTLALHELLEASERSAAVVGSLWS 6054 Query: 846 TTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQ 905 D R+ +++ Y G D+ P +++ LPTYPF+ +FW + A Sbjct: 6055 DEGDLRRFLVSLSELYVNGFALDWTTILPP-GKRVPLPTYPFQRERFWLDASTA-----P 6108 Query: 906 TASAGSVTPHRTQAVRLLEDGQIEELAAL--IDGETVDEQTLRVLNKLAA-RHNQQRSTH 962 A + P + + +E G I+ L+ +DG+ +L LA+ RH +Q Sbjct: 6109 AAGVNHLAPLEGRFWQAIESGNIDALSGQLHVDGDEQRAALALLLPTLASFRHERQEQGT 6168 Query: 963 VDPDARYEIRWDXXXXXXXXXXXXXDWILVG----DDTAAVLEFADALTAGGHRHQIVAL 1018 VD RY I W W+LV DD A +AL G R V L Sbjct: 6169 VDA-WRYRITWKPLTTATTPADLAGTWLLVVPAALDDDALPSALTEALARRGARVLAVRL 6227 Query: 1019 PGSDADEAQLVDTLRAA---SAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRA 1075 + D L + LR A +A V+ + A D +P+ D V L L +A Sbjct: 6228 SQAHLDREALAEHLRQACAETAPPRGVLSLLALD--ESPLADHAAVPAGLAFSLT-LVQA 6284 Query: 1076 ANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLSGA-D 1133 D L +P+WL TR V +D + P Q+ WG GR LE P WGGL D+ A D Sbjct: 6285 LGDIALDAPLWLFTRGAVSVGHSDPIAHPTQAMTWGLGRVVGLEHPERWGGLVDVGAAID 6344 Query: 1134 TEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGA 1193 + + + R+ EDQ+ALR YA RLVR + + T L+TGG GA Sbjct: 6345 ASAVGRLLPVLALRNDEDQLALRPAGFYARRLVRAPLGDAPPARTFKPRGTLLITGGTGA 6404 Query: 1194 IGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARL 1253 G VA +LA GA H+VL SRR V DVAD VA L Sbjct: 6405 AGAHVARWLAREGAEHLVLISRRGAQAEGASELHAELTALGARVTFAACDVADRSAVATL 6464 Query: 1254 MTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLD 1313 + + AE + + HA G PL+ E+ V + KV GA +L + L LD Sbjct: 6465 LEQLDAEGSQVRAVFHAGGIGRHAPLAATSLMELADVVSAKVLGAGNLHDLLGP--RPLD 6522 Query: 1314 FFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG--MADAES 1371 FV SSIA VWGG Q Y A NAFLD LA + R G SV +G W G + Sbjct: 6523 AFVLFSSIAGVWGGGQQAGYAAGNAFLDALADQRRSLGQPDTSVVWGAWGGGGGIFTGPL 6582 Query: 1372 RARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQAGRRAFLSELES 1430 A+LEQR + ++P+ A+A +A + V VA IDW+RF P A R + S Sbjct: 6583 AAQLEQRRLSPMAPSLAVAALAQALEHDETTVTVADIDWARFAPSISVARSRRSCATCPS 6642 Query: 1431 ELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDAD-EIRDE 1489 L+++L ++ L+ + + A V + R Sbjct: 6643 SAPSKTEKARPPPSTARPPDLLDKLRSRSESEQLRLLAALVCDETALVLGHEGRFPARPR 6702 Query: 1490 AGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYL---LVEVLGLGEQT 1546 GFFDLG+DS+M VELRRR++Q G +P TL DHP A ++ L LG Sbjct: 6703 QGFFDLGLDSIMTVELRRRLQQATGIKLPATLAFDHPSPHRVALFMRDSLAHALGTRLSA 6762 Query: 1547 NVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDRWDIDEFY 1605 + A +D+PIA+V ++ R PG D ++ WE L G DA+ +P+ RWD Y Sbjct: 6763 EATPPRSGRASSDEPIAIVGMALRLPGGVGDVDALWEFLHQGRDAVEPIPQSRWDAGALY 6822 Query: 1606 DPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYA 1665 DPDPD K+Y R P FFGISPREA ++PQ RL+LE+ W LE AG Sbjct: 6823 DPDPDADAKSYVRHAAMLDQIDLFDPAFFGISPREAKHLDPQHRLLLESAWLALEDAGIV 6882 Query: 1666 PSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAV 1725 P+ L+ S TGVF G+ A EYA + S + E +FI G + + +G +A+ LG +GP Sbjct: 6883 PTSLKDSLTGVFVGICAGEYA--MQEASSEGSEVYFIQGTSASFGAGGLAYTLGLQGPRS 6940 Query: 1726 AVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTF 1785 +VDTACSS+LV++H ACQAL+ G+C+LALA GV++++SP T V SR R L+P GR KTF Sbjct: 6941 SVDTACSSSLVSLHLACQALRQGECNLALAAGVSLMVSPQTFVILSRLRALAPDGRSKTF 7000 Query: 1786 DASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRL 1845 +ADGY R EG VL L+R+ DA+ RV ++ +++N DGASSG+T PNG +QQ++ Sbjct: 7001 SDNADGYGRGEGVVVLALERIGDALARRHRVLVLVRGTAINHDGASSGITAPNGTSQQKV 7060 Query: 1846 IEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIG 1905 + A L A ++ ADVD +E HGTGT LGDPIEVQ PLL+G++KTNIG Sbjct: 7061 LRAALHDARITPADVDVVECHGTGTSLGDPIEVQALAAVYADGRPAEKPLLLGALKTNIG 7120 Query: 1906 HTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPW--QTNGRV 1963 H E+ASG AG+ K+V SL+H LP +LH +P I W+AL + V+D P PW +G Sbjct: 7121 HLEAASGLAGVAKMVASLRHDALPPTLHATPRNPLIEWEALAIDVVDTPRPWPRHEDGSP 7180 Query: 1964 RRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV--LALSARSP 2021 RRAG+S+FGF+GTNAHV++EEAP L + +P + LSARS Sbjct: 7181 RRAGISAFGFSGTNAHVILEEAPAAL-------PAEPATSQPASQAAPAAWPVLLSARSE 7233 Query: 2022 EALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXX 2081 A+ A+R D L A L +ADV ++ R+HFE+RAALV + Sbjct: 7234 AAVRAQAKRLRDHLVAHDDLTLADVAYSLATTRAHFEHRAALVAHNRDELLSALDSLAQD 7293 Query: 2082 XTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRP 2141 V G ++F GQGSQ+ GMA L D+ PVF + C A+A + Sbjct: 7294 KPAPSTVLGRSGSHGKLVFVFPGQGSQWEGMALSLLDSSPVFRAQLEACERALAPHVEWS 7353 Query: 2142 LLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACV 2201 LL VL E A L QPALFAV + LA LW+S +EP V+GHS G+ AAA V Sbjct: 7354 LLAVL--RRDEGAPSLDRVDVVQPALFAVMVSLAALWRSLGVEPAAVVGHSQGEIAAAFV 7411 Query: 2202 AGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF-PRVSVGAYNGPN- 2259 AG SL+D AR+ A R + ++ G M AV A ++ + R+S+ A N P Sbjct: 7412 AGALSLEDAARIAALRSKALTTVAGNGAMAAVELGASDLQTYLAPWGDRLSIAAVNSPRA 7471 Query: 2260 TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLP 2319 T++SG ++ +++ + + +A HS +D V D LP Sbjct: 7472 TLVSGEPAAIDALIDSLTAAQVFARKVRVDYASHSAQMDAVQDELAAGLANIAPRTCELP 7531 Query: 2320 LVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAV 2379 L TG L G + LD YW R+ RQ V F+ + + G +E+ P PVLT A Sbjct: 7532 LYSTVTGTRLDG-SELDGAYWYRNLRQTVLFSSATERLLDDGHRFFVEVSPHPVLTLALR 7590 Query: 2380 QVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYP 2438 + P V S+R+ ++ + A G D+ A R V LPTYP Sbjct: 7591 ETCERSPLDPVVVGSIRRDEGHLARLLLSWAELSTRGLALDWNAFFAPFAPRKVSLPTYP 7650 Query: 2439 FQRRRFWPKASS-----IAVDGGTAAS-GILGSGKDLASGD-TIYTSRLSVKSQPWLADH 2491 FQR RFW AS+ +A G T+A +LG+ LA D ++T RLS+ PWL DH Sbjct: 7651 FQRERFWLDASTAHAADVASAGLTSADHPLLGAAVALADRDGFVFTGRLSLAEHPWLEDH 7710 Query: 2492 VIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGS 2548 V++G +AL VG ++DV P+ LP + + +Q+++ PADG Sbjct: 7711 VVFGIPCPARRRLLELALHVAHLVGLDT-VEDVTLDPPLALPSQGAVLLQISVGPADGAG 7769 Query: 2549 VLSFQIHSRPYGE-RGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDL 2607 + +HSR + + W+ +A G++ A P ++ Q Sbjct: 7770 RRALSVHSRRHDALQDGPWTRHASGSLAQASPSHCLRCSANGPP-----SGATQVDTQGF 7824 Query: 2608 FETFADLELAWGPTWSGSLKSL 2629 + LA+GP + G + L Sbjct: 7825 YAALESAGLAYGPEFQGLRRRL 7846 Score = 1515 bits (3923), Expect = 0.0 Identities = 984/2498 (39%), Positives = 1318/2498 (52%), Gaps = 98/2498 (3%) Query: 7 PIEPTPS---FAIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDP 61 P+ P S AI+ + RFPG + E+ W LL DG++AIS P++R W ++ Sbjct: 3663 PLTPGGSEDPIAIVAMSCRFPGDVRTPEDLWKLLLDGQDAISGFPQNRGWSLDAL----- 3717 Query: 62 STPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSL 121 PG+ R GFV D FD FFG+S RE +DPQ RIL+E W A E +GI P SL Sbjct: 3718 DAPGRFPVREGGFVYDADAFDPAFFGISPREALAVDPQQRILLEITWEAFERAGIDPASL 3777 Query: 122 ANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVD 181 S +GVFVG+ DY AS E + +A G++ + A+GRI+Y GLQGPA++VD Sbjct: 3778 QGSQSGVFVGVWQSDY--HASLVNATGEYKGLVATGSAASVASGRIAYTFGLQGPAISVD 3835 Query: 182 TACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAA 241 TACSSSLVA+H ACQALR EC LALAGG ++ TP I F + APDGRCK F A Sbjct: 3836 TACSSSLVAVHLACQALRHGECSLALAGGVTIMATPGIFIAFDSESAGAPDGRCKAFSAE 3895 Query: 242 ADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIAD 301 ADG EG G+++++RL DAV++G + AV+RGSA+NQDG S GLT PNG AQ+RVI Sbjct: 3896 ADGSGWAEGAGMLLLERLSDAVQNGHPVLAVLRGSAVNQDGRSQGLTAPNGPAQERVIRQ 3955 Query: 302 ALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLE 361 AL A L P DV +EAHGTGT+LGDPIEAQA G + + PL +GS K+N+GH + Sbjct: 3956 ALDSARLTPKDVDVVEAHGTGTTLGDPIEAQAVFATYGEAHSQDRPLWLGSLKSNLGHTQ 4015 Query: 362 XXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGV 421 L++ LPK L+ + PSPHI W ++++ E V W +G PR AGV Sbjct: 4016 AAAGVGGIIKMVLALQHGLLPKTLHAQNPSPHIDWSPGIVKLLNEAVAWTTSGHPRRAGV 4075 Query: 422 SSFGFAGTNAHVILEEAPAV--GTPATTEPVEDPRRYS-VLPLSARTPEALVRLAGEYRD 478 SSFG +GTNAHVILEEAPA ++P P + + LSAR+ A+ A R+ Sbjct: 4076 SSFGVSGTNAHVILEEAPAATRAESGASQPASQPLPAAWPVVLSARSEAAVRAQAQRLRE 4135 Query: 479 WLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESH 538 L A LADV+++ T RAH E RAALV + R+ + L +LA D+PAP V G S Sbjct: 4136 HLLAQGDLTLADVAYSLATTRAHFEHRAALVAHDRDELLSALDSLAQDKPAPSTVLGRSG 4195 Query: 539 EAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELD 598 K ++F GQGSQ+ GMA L D+ PVF + C A+ +E LL V L Sbjct: 4196 SHGKVVFVFPGQGSQWEGMALSLLDSSPVFRTQLEACERALRPHVEWSLLAV------LR 4249 Query: 599 GDTESP-LRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVED 657 D +P L QPALFAV + LA LW+S G EP VVGHS G+ +AA VAG +ED Sbjct: 4250 RDEGAPSLDRVDVVQPALFAVMVSLAALWRSLGVEPAAVVGHSQGEIAAAFVAGALSLED 4309 Query: 658 GARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGAN-TVLSGPAKD 716 AR+ A R + PA G A A + L LS+AA N T++SG Sbjct: 4310 AARIAALRSKASPPSPATGMAAVELGASDLQTYLAPWGDRLSIAAVNSPRATLVSGEPAA 4369 Query: 717 LESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSA 776 +++ + +L A V + +A HSA +D + D+ + + R + L TG+ Sbjct: 4370 VDALIDSLTAAQVFARRVRVDYASHSAQMDAVQDELAAGLANIAPRTCELPLYSTVTGTR 4429 Query: 777 LGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATT 836 L S LDGAYW R+ RQ V F+ + L D R +E+ P PVLT Sbjct: 4430 LDGS-ELDGAYWYRNLRQTVLFSSATERLLDDGHRFFVEVSPHPVLTLALRETCERSPLD 4488 Query: 837 PQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDA-RKLDLPTYPFEHRQFWFS 895 P V+ S+R ++ + A G P+++AF P A RK+ LPTY F+ +FW Sbjct: 4489 PVVVGSIRRDEGHLPRLLALLGRALWPGLTPEWKAFFAPFAPRKVSLPTYAFQRERFWLD 4548 Query: 896 DNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALI--DGETVDEQTLRVLNKLAA 953 A A A + QA+ E G ++ L+ + DG+ +L L++ Sbjct: 4549 APNA--HPEGVAPAAPIDGRFWQAI---ERGDLDALSGQLHADGDEQRAALALLLPTLSS 4603 Query: 954 RHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILV-----GDDTAAVLEFADALTA 1008 H+Q++ RY I W W+LV GDD A DALT Sbjct: 4604 FHHQRQEQSTVDTWRYRITWRPLTTAATPADLAGTWLLVVPSALGDD-ALPATLTDALTR 4662 Query: 1009 GGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMR---DLLRVQHRT 1065 G R + L A L + LR A A AP+R LL + R Sbjct: 4663 RGARVLALRLSQVHIGRAALTEHLREAVA-------------ETAPIRGVLSLLALDERP 4709 Query: 1066 L-------GGLR---RLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRA 1114 L GL L +A D L +P+WL TR + +D + P Q+ +WG GR Sbjct: 4710 LADHAALPAGLALSLALVQALGDLALEAPLWLFTRGAVSIGHSDPLAHPTQAMIWGLGRV 4769 Query: 1115 AALELPHIWGGLADLSGA-DTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPS 1173 LE P WGGL DL A D + + R EDQ+ALR +YA R VR + Sbjct: 4770 VGLEHPERWGGLVDLGAALDASAAGRLLPALAQRHDEDQLALRPAGLYARRFVRAPLGDA 4829 Query: 1174 DTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQY 1233 T L+TGG GAIG VA +LA GA H+VL SRR Sbjct: 4830 PAARGFMPRGTILITGGTGAIGAHVARWLARKGAEHLVLISRRGAQAEGAVELHAELTAL 4889 Query: 1234 ACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAG 1293 V DVAD VA L+ + A P ++ + HA G PL+ ++ V +G Sbjct: 4890 GARVTFAACDVADRSAVATLLEQLDAGGPQVSAVFHAGGIEPHAPLAATSMEDLAEVVSG 4949 Query: 1294 KVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVT 1353 KV GA HL + L LD FV SS A VWGG Q Y AANAFLD LA + R G+T Sbjct: 4950 KVQGARHLHDLLGS--RPLDAFVLFSSGAVVWGGGQQGGYAAANAFLDALAEQRRSLGLT 5007 Query: 1354 AVSVNFGPW-AAGMADAESRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSR 1411 A SV +G W GMA A+LEQRG+ ++P+ A+A +A + VA IDW+R Sbjct: 5008 ATSVAWGVWGGGGMATGLLAAQLEQRGLSPMAPSLAVATLALALEHDETTLTVADIDWAR 5067 Query: 1412 FLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYL 1471 F P + A R L +L L+++L ++ L+++ + Sbjct: 5068 FAPSFSAARSRPLLRDLPEAQRALEASADASSEQDGATGLLDKLRNRSESEQIHLLSSLV 5127 Query: 1472 RNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSD 1530 R+ A V DA ++ GF DLG+DSLM VELRRR++Q G +P TL DHP Sbjct: 5128 RHEAALVLGHTDASQVDPHKGFMDLGLDSLMTVELRRRLQQATGIKLPATLAFDHPSPHR 5187 Query: 1531 AADYL---LVEVLG--LGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELL 1584 A +L L LG L + + + + +D+PIA+V ++ R PG D ++ WE L Sbjct: 5188 VALFLRDSLAHALGARLSVERDAAALPALRSASDEPIAIVGMALRLPGGIGDVDALWEFL 5247 Query: 1585 AGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWI 1644 A G DA+ +P RWD YDPDPD K+Y R P FFGISPREA ++ Sbjct: 5248 AQGRDAVEPIPHARWDAGALYDPDPDAKAKSYVRHAAMLDQVDLFDPAFFGISPREAKYL 5307 Query: 1645 EPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITG 1704 +PQ RL+LE+ W LE AG PS L+ S TGVF G+ A+EYA L S +++E + + G Sbjct: 5308 DPQHRLLLESAWLALEDAGIVPSTLKDSPTGVFVGIGASEYA--LRNTSSEEVEAYALQG 5365 Query: 1705 NALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSP 1764 A + +GR+A+ LG +GPA++VDTACSS+LVA+H ACQAL+ G+C+LALA GV+V+ SP Sbjct: 5366 TAGSFAAGRLAYTLGLQGPALSVDTACSSSLVALHLACQALRQGECNLALAAGVSVMASP 5425 Query: 1765 VTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASS 1824 V SR R L+P GR KTF +ADGY R EG VL L+RL DA+ G RV A++ ++ Sbjct: 5426 GLFVVLSRMRALAPDGRSKTFSTNADGYGRGEGVVVLALERLGDALARGHRVLALVRGTA 5485 Query: 1825 VNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXX 1884 +N DGASSG+T PNG + Q+++ A L A + ADVD +E HGTGT LGDPIEVQ Sbjct: 5486 MNHDGASSGITAPNGTSHQKVLRAALHDAHIGPADVDVVECHGTGTSLGDPIEVQALAAV 5545 Query: 1885 XXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWD 1944 PLL+G++KTNIGH E+ASG AG+ K+V SL+H LP +LH +P I WD Sbjct: 5546 YADGRPAEKPLLLGALKTNIGHLEAASGLAGVAKIVASLRHDALPPTLHTTPRNPLIEWD 5605 Query: 1945 ALPVRVIDEPVPW--QTNGRVRRAGVSSFGFTGTNAHVLVEEAP--PQLHXXXXXXXXXX 2000 AL + V+D W +G RRAGVS+FG +GTNAHV++EEAP PQ Sbjct: 5606 ALAIDVVDATRAWARHEDGSPRRAGVSAFGLSGTNAHVILEEAPAIPQAEPTAAQLASQP 5665 Query: 2001 XXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYR 2060 + + LSARS A+ A+R D L A L +ADV ++ R+ FE+R Sbjct: 5666 L-------PAAWPVLLSARSEPAVRAQAQRLRDHLLAHDDLALADVAYSLATTRATFEHR 5718 Query: 2061 AALVV-DSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDT 2119 AALVV D P+ VV H ++F GQGSQ+ GMA L DT Sbjct: 5719 AALVVHDREELLSALDSLAQGRPAPSTVVERSGSH-GKVVFVFPGQGSQWEGMALSLLDT 5777 Query: 2120 QPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQ 2179 PVF + C A+A + LL VL E A L QPALF++ + LA LW+ Sbjct: 5778 SPVFRAQLEACERALAPHVDWSLLAVL--RGEEGAPPLDRVDVVQPALFSMMVSLAALWR 5835 Query: 2180 SWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAV-FADAE 2238 S +EPD V+GHS G+ AAACVAG SL+D A+L+A R R L G M AV +AE Sbjct: 5836 SMGVEPDAVVGHSQGEIAAACVAGALSLEDAAKLVALRSRALVELAGQGAMAAVELPEAE 5895 Query: 2239 HVEQVAGEFPRVSVGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELL 2297 ++ R+S+GA N P T +SG + ++ E EG+ L+ A HS + Sbjct: 5896 VARRLQRYGDRLSIGAINSPRFTTISGEPPAVAALLRDLESEGVFALKLSYDFASHSAQV 5955 Query: 2298 DPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTV 2357 + + D +P +GA + G + LDA YW R+ RQPV+FA++V+ + Sbjct: 5956 ESIRDELLDLLSWLEPRSTAVPFYSTVSGAAIDG-SELDAAYWYRNLRQPVRFADAVQGL 6014 Query: 2358 AALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGH 2417 A +E+ P PVLT A ++ + V SL D R+ +L+ YV G Sbjct: 6015 LAGEHRFFVEVSPSPVLTLALHELLEASERSAAVVGSLWSDEGDLRRFLVSLSELYVNGF 6074 Query: 2418 RPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDG 2455 D+ + P + V LPTYPFQR RFW AS+ G Sbjct: 6075 ALDWTTI-LPPGKRVPLPTYPFQRERFWLDASTAPAAG 6111 Score = 746 bits (1926), Expect = 0.0 Identities = 486/1309 (37%), Positives = 679/1309 (51%), Gaps = 53/1309 (4%) Query: 1176 PLPVREDRTYLVTGGLGAIGLEVAGYL-ASHGAGHVVLTSRREPXXXXXXXXXXXXEQYA 1234 P P+ + T L+TGG G +G+ VA +L A H A H++LTSR+ E Sbjct: 3290 PRPIDPEGTVLITGGTGTLGVLVARHLVAKHSAKHLLLTSRKGARAPGAEALRSELEALG 3349 Query: 1235 CDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGK 1294 V ++ DVAD + L+ ++ + P+ +VHAAG + PL + + RVF K Sbjct: 3350 ASVTLVACDVADPRALRTLLDSIPRD-HPITAVVHAAGALDDGPLGSMSAERIARVFDPK 3408 Query: 1295 VWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTA 1354 + AW+L E D + FV S+ + V GG GQ+ Y AANAFLD LA R +G+ A Sbjct: 3409 LDAAWYLHELTQD--EPVAAFVLFSAASGVLGGPGQSNYAAANAFLDALAHHRRAQGLPA 3466 Query: 1355 VSVNFGPWA--AGMA---DAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGVV-AKID 1408 S+ +G WA +GM A AR+ + GVR L EAL+ + P +V A D Sbjct: 3467 ASLAWGYWAERSGMTRHLSAADAARMRRAGVRPLDTDEALSLFDVALLRPEPALVPAPFD 3526 Query: 1409 WSRFL-------PLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQ 1461 ++ PL+Q+ R + S L E L+ P Sbjct: 3527 YNVLSTSADGVPPLFQRLVRARIARKAASNTALASS-------------LAEHLSSLPPA 3573 Query: 1462 QRKSLITNYLRNAVAEVTRVDADEIRD-EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVT 1520 +R+ ++ + +R A V + + E D +LG+DSLMA+ELR R+ G + T Sbjct: 3574 ERERVLLDLVRTEAASVLGLASFESLDPHRPLQELGLDSLMALELRNRLAAAAGLRLQAT 3633 Query: 1521 LVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVT-ARTDDPIAVVAVSCRFPG-APDPE 1578 L+ D+P + + + + G T R +T ++DPIA+VA+SCRFPG PE Sbjct: 3634 LLFDYPTPTALSRFFTTHLFG---GTTHRPGVPLTPGGSEDPIAIVAMSCRFPGDVRTPE 3690 Query: 1579 SFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGIS 1637 W+LL G DAI P++R W +D D PG+ R P FFGIS Sbjct: 3691 DLWKLLLDGQDAISGFPQNRGWSLDAL-----DAPGRFPVREGGFVYDADAFDPAFFGIS 3745 Query: 1638 PREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKI 1697 PREA+ ++PQQR++LE WE ERAG P+ L+GS++GVF GV ++Y H + + Sbjct: 3746 PREALAVDPQQRILLEITWEAFERAGIDPASLQGSQSGVFVGVWQSDY-HASLVNATGEY 3804 Query: 1698 EPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGG 1757 + TG+A + SGR+A+ G +GPA++VDTACSS+LVAVH ACQAL+ G+C LALAGG Sbjct: 3805 KGLVATGSAASVASGRIAYTFGLQGPAISVDTACSSSLVAVHLACQALRHGECSLALAGG 3864 Query: 1758 VNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVC 1817 V ++ +P +A +P GRCK F A ADG +EG G+L+L+RLSDAV++G V Sbjct: 3865 VTIMATPGIFIAFDSESAGAPDGRCKAFSAEADGSGWAEGAGMLLLERLSDAVQNGHPVL 3924 Query: 1818 AVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIE 1877 AV+ S+VNQDG S GLT PNG AQ+R+I L A L+ DVD +EAHGTGT LGDPIE Sbjct: 3925 AVLRGSAVNQDGRSQGLTAPNGPAQERVIRQALDSARLTPKDVDVVEAHGTGTTLGDPIE 3984 Query: 1878 VQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENP 1937 Q PL +GS+K+N+GHT++A+G G+IK+VL+LQHG+LP++LH +NP Sbjct: 3985 AQAVFATYGEAHSQDRPLWLGSLKSNLGHTQAAAGVGGIIKMVLALQHGLLPKTLHAQNP 4044 Query: 1938 SPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXX 1997 SPHI W V++++E V W T+G RRAGVSSFG +GTNAHV++EEAP Sbjct: 4045 SPHIDWSPGIVKLLNEAVAWTTSGHPRRAGVSSFGVSGTNAHVILEEAPAATRAESGASQ 4104 Query: 1998 XXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHF 2057 + + LSARS A+ A+R + L A L +ADV ++ R+HF Sbjct: 4105 PASQPL-----PAAWPVVLSARSEAAVRAQAQRLREHLLAQGDLTLADVAYSLATTRAHF 4159 Query: 2058 EYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELF 2117 E+RAALV V G ++F GQGSQ+ GMA L Sbjct: 4160 EHRAALVAHDRDELLSALDSLAQDKPAPSTVLGRSGSHGKVVFVFPGQGSQWEGMALSLL 4219 Query: 2118 DTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARL 2177 D+ PVF + C A+ + LL VL E A L QPALFAV + LA L Sbjct: 4220 DSSPVFRTQLEACERALRPHVEWSLLAVL--RRDEGAPSLDRVDVVQPALFAVMVSLAAL 4277 Query: 2178 WQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADA 2237 W+S +EP V+GHS G+ AAA VAG SL+D AR+ A R + P G + Sbjct: 4278 WRSLGVEPAAVVGHSQGEIAAAFVAGALSLEDAARIAALRSKASPPSPATGMAAVELGAS 4337 Query: 2238 EHVEQVAGEFPRVSVGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSEL 2296 + +A R+S+ A N P T++SG ++ +++ + + +A HS Sbjct: 4338 DLQTYLAPWGDRLSIAAVNSPRATLVSGEPAAVDALIDSLTAAQVFARRVRVDYASHSAQ 4397 Query: 2297 LDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRT 2356 +D V D LPL TG L G + LD YW R+ RQ V F+ + Sbjct: 4398 MDAVQDELAAGLANIAPRTCELPLYSTVTGTRLDG-SELDGAYWYRNLRQTVLFSSATER 4456 Query: 2357 VAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGG 2416 + G +E+ P PVLT A + P V S+R+ ++ L A G Sbjct: 4457 LLDDGHRFFVEVSPHPVLTLALRETCERSPLDPVVVGSIRRDEGHLPRLLALLGRALWPG 4516 Query: 2417 HRPDFAAVHRQ-PRRPVELPTYPFQRRRFWPKASSIAVDGGTAASGILG 2464 P++ A R V LPTY FQR RFW A + +G A+ I G Sbjct: 4517 LTPEWKAFFAPFAPRKVSLPTYAFQRERFWLDAPNAHPEGVAPAAPIDG 4565 Score = 660 bits (1704), Expect = 0.0 Identities = 393/906 (43%), Positives = 527/906 (58%), Gaps = 25/906 (2%) Query: 1554 VTARTDDPIAVVAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDT 1611 V + +PIA+VA+SCRFPG PE W+LL G DAI ++P +R W +D D Sbjct: 28 VEEKEHEPIAIVAMSCRFPGDVRTPEDLWKLLLDGKDAISDLPPNRGWKLDAL-----DV 82 Query: 1612 PGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRG 1671 G++ R P FFGISPREA+ I+PQQRL+LE WE ERAG P+ L+G Sbjct: 83 HGRSPVREGGFFYDADAFDPAFFGISPREALAIDPQQRLLLEISWEAFERAGIDPASLQG 142 Query: 1672 SRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTAC 1731 S++GVF GV N+Y LL + + + TG+ + SGR+A+ GF+GPA++VDTAC Sbjct: 143 SQSGVFVGVIHNDYDALLE-NAAGEHKGFVATGSTASVASGRIAYTFGFQGPAISVDTAC 201 Query: 1732 SSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADG 1791 SS+LVAVH ACQAL+ G+C LALAGGV V+ +P VA +P GRCK+F A+G Sbjct: 202 SSSLVAVHLACQALRRGECSLALAGGVTVMATPAVFVAFDSESAGAPDGRCKSFSVEANG 261 Query: 1792 YVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLA 1851 +EG G+L+L+RLSDAV++G V AV+ S+VNQDG S GLT PNG AQ+R+I L Sbjct: 262 SGWAEGAGMLLLERLSDAVQNGHPVLAVLRGSAVNQDGRSQGLTAPNGPAQERVIRQALD 321 Query: 1852 RAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESAS 1911 A L+ DVD +EAHGTGT LGDPIE Q PL +GS+K+N+GH ++A+ Sbjct: 322 SARLTPKDVDVVEAHGTGTTLGDPIEAQAILATYGEAHSQDRPLWLGSLKSNLGHAQAAA 381 Query: 1912 GAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSF 1971 G +IK+VL+LQ G+LP++LH +NPSPHI W V++++EPV W TNG R AGVS+F Sbjct: 382 GVGSVIKMVLALQQGLLPKTLHAQNPSPHIDWSPGTVKLLNEPVVWTTNGHPRHAGVSAF 441 Query: 1972 GFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV--LALSARSPEALVELAR 2029 G +GTNAHV++EEAP ++ P + LSA+S A+ A+ Sbjct: 442 GISGTNAHVILEEAP-------AIARVEPAASQPASEPLPAAWPVLLSAKSEAAVRAQAK 494 Query: 2030 RYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVR 2089 R D L A L +ADV ++ R+HFE RAAL+V + A V Sbjct: 495 RLRDHLLAKSELALADVAYSLATTRAHFEQRAALLVKGRDELLSALDALAQGHSAA--VL 552 Query: 2090 GEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFAT 2149 G A LFTGQGSQ P M R L+D PVF + + L RPL DVLFA Sbjct: 553 GRSGAPGKLAVLFTGQGSQRPTMGRGLYDVFPVFRDALDTVGAHLDRELDRPLRDVLFAP 612 Query: 2150 D-RETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLD 2208 D E A L+ T+F QPALFA+E+ L +L QS+ ++P ++LGHS+G+ AA VAGV SL Sbjct: 613 DGSEQAARLEQTAFTQPALFALEVALFQLLQSFGLKPALLLGHSIGELVAAHVAGVLSLQ 672 Query: 2209 DGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFP-RVSVGAYNGP-NTVLSGPG 2266 DG L+A R ++ +LP+GG MV + A E V + + R S+ A NGP +TV++G Sbjct: 673 DGCTLVAARAKLMQALPQGGAMVTLRASEEEVRDLLQPYEGRASLAALNGPLSTVVAGDE 732 Query: 2267 EDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTG 2326 + + EI + E G + T L SHAFHS +D +LD +P++ N TG Sbjct: 733 DAVVEIARQAEALGRKTTRLRVSHAFHSPHMDGMLDDFRRVAQSLTYHPARIPIISNVTG 792 Query: 2327 AVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ-VWPEH 2385 A T YW RH R V+F + VR + A G V +E+GP VL+ A + + Sbjct: 793 ARATDHELASPDYWVRHVRHTVRFLDGVRALHAEGARVFLELGPHAVLSALAQDALGQDE 852 Query: 2386 MAAPRA-VASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRR 2443 +P A + +LRKG D AL + + G PD++A R V LPTY FQR R Sbjct: 853 GTSPCAFLPTLRKGRDDAEAFTAALGALHSAGITPDWSAFFAPFAPRKVSLPTYAFQRER 912 Query: 2444 FWPKAS 2449 FWP AS Sbjct: 913 FWPDAS 918 Score = 162 bits (409), Expect = 1e-36 Identities = 146/505 (28%), Positives = 218/505 (43%), Gaps = 36/505 (7%) Query: 1052 AAPMRDLLRVQHRTLGGLRRLFRA--ANDAELRSPIWLVTRDGQRV-TDTDTVVPEQSCL 1108 A P DL+ T L +A A++ S + LVTR + D + L Sbjct: 8030 ALPEGDLIASARETTAHALALLQAWLADERLASSRLALVTRRAVATHAEEDVKGLAHAPL 8089 Query: 1109 WGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRR 1168 WG R+A E P L DL ++ L+ + + E +IALR PRL R Sbjct: 8090 WGLARSAQSEHPERPLVLVDLDDSEASQHALLGALDAR---EPEIALRNGKPLVPRLSRL 8146 Query: 1169 TGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLA-SHGAGHVVLTSRREPXXXXXXXXX 1227 P+DT P T L+TGG G +G VA L +H A H++LTSR+ Sbjct: 8147 PQAPTDTASPAGLGGTVLITGGTGTLGALVARRLVVNHDAKHLLLTSRQGASAPGADVLR 8206 Query: 1228 XXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEV 1287 E V + DVAD + L+ + + P+A +VHAA + L + + Sbjct: 8207 SELEALGASVTLAACDVADPRALKDLLDNIPSA-HPVAAVVHAASVLDGDLLGAMSLERI 8265 Query: 1288 DRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRL 1347 DRVFA K+ AWHL + D L F+ SS+A V G G + Y AA+AFLD LA Sbjct: 8266 DRVFAPKIDAAWHLHQLTQD--KPLAAFILFSSVAGVLGSSGHSNYAAASAFLDALAHHR 8323 Query: 1348 RERGVTAVSVNFGPWAAGMA-----DAESRARLEQRGVRTLSPAEALAGMADVVAGPVQG 1402 R +G+ A S+ + WA A A R+E+ G+ + S A + Sbjct: 8324 RAQGLPASSLAWSHWAERSAMTEHVSAAGAPRMERAGLPSTSEERLALFDAALFRTETAL 8383 Query: 1403 VVAKIDWSRFL-------PLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQL 1455 V A+ D S PL+Q+ R + + S L E+L Sbjct: 8384 VPARFDLSALRANAGSVPPLFQRLVRARTVRKAASN-------------TAQASSLTERL 8430 Query: 1456 TKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFF-DLGMDSLMAVELRRRIEQGVG 1514 + P +R+ + + +R A V + + E D +LG+DS++A++LR R+ G Sbjct: 8431 SALPPAERERALLDLIRTEAAAVLGLASFESLDPDRLLQELGLDSIIALDLRNRLAAATG 8490 Query: 1515 KDIPVTLVMDHPRLSDAADYLLVEV 1539 +P TL+ +HP + A LL + Sbjct: 8491 VRLPATLLFEHPTPAALAALLLARL 8515 Score = 151 bits (381), Expect = 2e-33 Identities = 120/361 (33%), Positives = 162/361 (44%), Gaps = 15/361 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GAIG H A +LA+ GA +VL SRR + + + R A DV Sbjct: 1210 LITGGTGAIGAHVARWLARRGAQHLVLISRRGAEAPGASELHDELSALGARTTLAACDVA 1269 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D VA LL ++ AE + + H +G+ A L A + ++ K GA H Sbjct: 1270 DRNAVATLLEQLDAEGSQVRAVFHASGIEHHAPLDATSFRDLAEVVSGKVEGAKHLHDLL 1329 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 Q YA ANA LD L RR+ GL AT + +G WG GGM Sbjct: 1330 GSRPLDAFVLFSSGAAVWGGGQQGGYAAANAFLDALAEHRRSAGLTATSVAWGAWGGGGM 1389 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 A+ +AA A++ +GL + PS AL ALA + + TV +W R A +ARP L Sbjct: 1390 ATDQAA-AHLQQRGLSRMAPSLALAALALALEHDETTVTVADIDWARFAPSFSAARPRPL 1448 Query: 3538 DLVLP----------SAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL--RLA 3585 LP A+ E +LL +L ++ + ++ E L A Sbjct: 1449 LRDLPEAQRALETSEGASSEHGPAPDLLDKLRSRSESEQLRLLVSLVRHETALVLGHEGA 1508 Query: 3586 SPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPD 3645 S FLDLG DSLMA+ELR RL G K + AT FD+P+ +A +L L Sbjct: 1509 SHVDPDKGFLDLGLDSLMAVELRRRLQQATGIK--LPATLAFDHPSPHRVALFLRDSLAH 1566 Query: 3646 A 3646 A Sbjct: 1567 A 1567 Score = 149 bits (377), Expect = 6e-33 Identities = 122/362 (33%), Positives = 168/362 (46%), Gaps = 17/362 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPD-ESAQRAIDEITERHKCRIHTYAADV 3356 LITGG GAIG H A +LA+ GA +VL SRR E A E+T R+ A DV Sbjct: 4842 LITGGTGAIGAHVARWLARKGAEHLVLISRRGAQAEGAVELHAELTALG-ARVTFAACDV 4900 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D + VA LL ++ A P ++ + H G+ A L+A + E ++ K GA H Sbjct: 4901 ADRSAVATLLEQLDAGGPQVSAVFHAGGIEPHAPLAATSMEDLAEVVSGKVQGARHLHDL 4960 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 Q YA ANA LD L +RR+ GL AT + +G WG GG Sbjct: 4961 LGSRPLDAFVLFSSGAVVWGGGQQGGYAAANAFLDALAEQRRSLGLTATSVAWGVWGGGG 5020 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA--RP 3534 MA+ A A + +GL P+ PS A+ LA + + TV +W R A +A RP Sbjct: 5021 MATGLLA-AQLEQRGLSPMAPSLAVATLALALEHDETTLTVADIDWARFAPSFSAARSRP 5079 Query: 3535 PILDLVLPSAAGEATGDSE--------LLKQLMEIPIPQRAGFVTEFLQREVQNFL--RL 3584 + DL A EA+ D+ LL +L ++ ++ ++ E L Sbjct: 5080 LLRDLPEAQRALEASADASSEQDGATGLLDKLRNRSESEQIHLLSSLVRHEAALVLGHTD 5139 Query: 3585 ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLP 3644 AS F+DLG DSLM +ELR RL G K + AT FD+P+ +A +L L Sbjct: 5140 ASQVDPHKGFMDLGLDSLMTVELRRRLQQATGIK--LPATLAFDHPSPHRVALFLRDSLA 5197 Query: 3645 DA 3646 A Sbjct: 5198 HA 5199 Score = 125 bits (315), Expect = 1e-25 Identities = 108/362 (29%), Positives = 154/362 (42%), Gaps = 16/362 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPD-ESAQRAIDEITERHKCRIHTYAADV 3356 LITGG GA G H A +LA+ GA +VL SRR E A E+T R+ A DV Sbjct: 6397 LITGGTGAAGAHVARWLAREGAEHLVLISRRGAQAEGASELHAELTALG-ARVTFAACDV 6455 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D + VA LL ++ AE + + H G+ A L+A + ++ K GA + Sbjct: 6456 ADRSAVATLLEQLDAEGSQVRAVFHAGGIGRHAPLAATSLMELADVVSAKVLGAGNLHDL 6515 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 QA YA NA LD L +RR+ G T + +G WG GG Sbjct: 6516 LGPRPLDAFVLFSSIAGVWGGGQQAGYAAGNAFLDALADQRRSLGQPDTSVVWGAWGGGG 6575 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPI 3536 + A + + L P+ PS A+ ALA+ + + TV +W R A + AR Sbjct: 6576 GIFTGPLAAQLEQRRLSPMAPSLAVAALAQALEHDETTVTVADIDWARFAPSISVARSRR 6635 Query: 3537 LDLVLPSAAGEATGDS----------ELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 PS+A T + +LL +L ++ + + E L Sbjct: 6636 SCATCPSSAPSKTEKARPPPSTARPPDLLDKLRSRSESEQLRLLAALVCDETALVLGHEG 6695 Query: 3587 --PPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLP 3644 P F DLG DS+M +ELR RL G K + AT FD+P+ +A ++ L Sbjct: 6696 RFPARPRQGFFDLGLDSIMTVELRRRLQQATGIK--LPATLAFDHPSPHRVALFMRDSLA 6753 Query: 3645 DA 3646 A Sbjct: 6754 HA 6755 Score = 109 bits (273), Expect = 7e-21 Identities = 108/367 (29%), Positives = 155/367 (42%), Gaps = 36/367 (9%) Query: 3298 LITGGLGAIGLHTAAYLA-QLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 LITGG G +G A L A ++LTSR+ + E + A DV Sbjct: 8164 LITGGTGTLGALVARRLVVNHDAKHLLLTSRQGASAPGADVLRSELEALGASVTLAACDV 8223 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D + DLL I + P+A + H A VLD LL A + ER APK A H Sbjct: 8224 ADPRALKDLLDNIPSA-HPVAAVVHAASVLDGDLLGAMSLERIDRVFAPKIDAAWHLHQL 8282 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 G +NYA A+A LD L RRAQGL A+ + + W Sbjct: 8283 TQDKPLAAFILFSSVAGVLGSSGHSNYAAASAFLDALAHHRRAQGLPASSLAWSHW---- 8338 Query: 3477 MASSEAATANITAQGLIPLD----PS----------AALHALAEVIANGSGQATVLKANW 3522 A A T +++A G ++ PS AAL + + L+AN Sbjct: 8339 -AERSAMTEHVSAAGAPRMERAGLPSTSEERLALFDAALFRTETALVPARFDLSALRAN- 8396 Query: 3523 QRAAKVLGSARPPILDLV----LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREV 3578 GS P LV + AA S L ++L +P +R + + ++ E Sbjct: 8397 ------AGSVPPLFQRLVRARTVRKAASNTAQASSLTERLSALPPAERERALLDLIRTEA 8450 Query: 3579 QNFLRLASPPAASSRFL--DLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLA 3636 L LAS + L +LG DS++A++LRNRL + G + + AT +F++PT LA Sbjct: 8451 AAVLGLASFESLDPDRLLQELGLDSIIALDLRNRLAAATGVR--LPATLLFEHPTPAALA 8508 Query: 3637 EYLVGQL 3643 L+ +L Sbjct: 8509 ALLLARL 8515 Score = 42.0 bits (97), Expect = 1.8 Identities = 57/198 (28%), Positives = 75/198 (37%), Gaps = 24/198 (12%) Query: 2761 LYTLGWHEVPPPPSADDAVGTWLIA--GFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHA 2818 L+ + W E+ P S A L+ G D L +VP +DR TDL L L Q Sbjct: 7965 LFRIDWSELQSPTSPPIAPSGALLGTEGLD-LGTRVP----LDRYTDLAALRSALDQ--- 8016 Query: 2819 RGAGFSGVVWR--CATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIV 2876 GA +V A P + L+ + A L +V Sbjct: 8017 -GASPPSLVIAPFIALP-------EGDLIASARETTAHALALLQAWLADERLASSRLALV 8068 Query: 2877 TEHGVACESGEPVDPV-QAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPG 2935 T VA + E V + A LWG R+ +E P LVD D S + Sbjct: 8069 TRRAVATHAEEDVKGLAHAPLWGLARSAQSEHPERPLVLVDLDDSEASQHALLGAL---D 8125 Query: 2936 IQEPEIAVRQGKLLASRL 2953 +EPEIA+R GK L RL Sbjct: 8126 AREPEIALRNGKPLVPRL 8143 >tr|B1W4J4|B1W4J4_STRGG Tax_Id=455632 (pks2-4)SubName: Full=Putative type-I PKS;[Streptomyces griseus subsp. griseus] Length = 3723 Score = 1889 bits (4894), Expect = 0.0 Identities = 1350/3717 (36%), Positives = 1841/3717 (49%), Gaps = 215/3717 (5%) Query: 15 AIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G + RFPG S E+ W + G +AI+ PKDR WD++ F D G T Sbjct: 43 AIVGMSCRFPGDVRSPEDLWDFVAAGGDAIAGFPKDRGWDLDTLFATDADGAGTSSTAAG 102 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GFV D FDA FFG+S RE MDPQ R+++E +W A+E +GI ++L NS+TGVF+G Sbjct: 103 GFVYDAGEFDAGFFGISPREALAMDPQQRLVLECSWEAIERAGIDVSTLRNSSTGVFLGA 162 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 + +Y G +D+ E Y G + + +GR++Y GL+GPAV VDTACSSSLVA+H Sbjct: 163 SAQNY-GTFADQGGEGS-EGYFLTGNAASVVSGRLAYVFGLEGPAVTVDTACSSSLVALH 220 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC LA+AGG V+ TP + FS LAPDGRCK F A ADG GEG G Sbjct: 221 LAAQALRAGECGLAVAGGVAVMSTPGAFVEFSRQRGLAPDGRCKPFAAGADGTGWGEGAG 280 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V++++RL DAV +G ++ AV+RGSA+NQDGAS GLT PNG +QQRVI AL AGL + Sbjct: 281 VLLLERLSDAVANGHQVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALSNAGLGTGE 340 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R PL +GS K+NIGH + Sbjct: 341 VDVVEAHGTGTKLGDPIEAQALLATYGQDRPEGRPLWLGSVKSNIGHTQAAAGVAGVIKM 400 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP+ L+ + PSPH+ W + ++ E VPW +G+ R AGVSSFG +GTNAH Sbjct: 401 VMAMRHGLLPETLHVDEPSPHVDWSAGEVRLLTEAVPWPADGRQRRAGVSSFGVSGTNAH 460 Query: 433 VILEEAPAVG-TPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADV 491 VILEEAPAV P T V P + V S R L A ++++ Q DV Sbjct: 461 VILEEAPAVEPAPEPTVVVSGPVPWLV---SGRGDAGLRGQAARLAEFVQGRDQD--VDV 515 Query: 492 SHTAGT--ARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTG 549 + A RA LE RA +V + L LA G+V G S K+A LFTG Sbjct: 516 AGVAAALMGRAVLENRAVVVGEGVADLVARLDVLAGGGLVDGVVCG-SPVGGKSAVLFTG 574 Query: 550 QGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTT 609 QGSQ+ GM L+ VFA V + +L +PL V+F +G + T Sbjct: 575 QGSQFAGMGAGLYGRFGVFAGVVDEVCAVADGLLPEPLRPVLFG----EGGRGGLIDRTV 630 Query: 610 YAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLF 669 +AQ L A+E+GL R+ G DV+VGHSVG+ SAA +GV + D RL+ RGRL Sbjct: 631 FAQVGLVALEVGLWRVLVECGVRADVLVGHSVGEVSAAVASGVLSLADAVRLVCVRGRLM 690 Query: 670 GSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLVADG 728 +PAGG M +V E + VAA N + VL+G + V LVA+G Sbjct: 691 EEVPAGGVMVSVAAPEEVVRGRVVGVAGVWVAAVNAPGSVVLAGEEGAVRGVVDGLVAEG 750 Query: 729 VRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYW 788 VR WL SHAFH+ L+DP+L++F L ++EP+ ++ TG G G YW Sbjct: 751 VRTRWLPVSHAFHTPLMDPVLEEFSREIAGLSFQEPRIPVVSTVTGEVAGAGFGSAG-YW 809 Query: 789 RRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTA 848 HAR+PV FA +V + RV E+GP+P L+A D V + LR Sbjct: 810 VEHARRPVRFADAVGVARGLGVRVWAEVGPQPALSAAL-----DVREGEVVASFLRRDRD 864 Query: 849 DHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTAS 908 + ++ + G + + +++PTY F+ R++W + R + Sbjct: 865 QATSLLTGLSRLHVHGVDVAWDQWVSRTGPLVEVPTYAFQRRRYWLEGSA---RSVVGSD 921 Query: 909 AGSVTPHRTQAVRLLEDGQIEELAAL-IDGETVDEQTLRVLNKLAARHNQQRSTHVDPDA 967 + T +AV + +L AL +DG+T ++ L VL + +R H Sbjct: 922 VDASTAEFWEAV------ERNDLRALGLDGDTPSDRVLPVLTEW---RRGRREHHALAGL 972 Query: 968 RYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQ 1027 RY + W W+++ E A+ G + + +P DE + Sbjct: 973 RYHVTWKPVPEPAAPTTLTGTWLVLTRPDDQAPEVIGAVGRAGGQTVRITVPVDVTDE-E 1031 Query: 1028 LVDTLRAAS------AGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAEL 1081 L L A S +G L ++ +A G GA + T+ L RA + A + Sbjct: 1032 LSRRLIAVSGDTITPSGVLSLLAVADGAGAETEPEAFPDLLPGTVTDTVTLLRALDAAGV 1091 Query: 1082 RSPIWLVTRDGQRVTDTD-TVVPEQSCLWGFGRAAALELPHIWGGLADLSGA-DTEWPRL 1139 +P+W VTR +D + T P + +WG GR AALE P WGGL DL D L Sbjct: 1092 DAPLWSVTRGAVSTSDDEPTRDPAAALVWGMGRVAALEQPGRWGGLIDLPAVTDENTYDL 1151 Query: 1140 IARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVA 1199 + R+ + D EDQ+A+R V A R+ R G + T R T L+TGG GA+G VA Sbjct: 1152 VCRVLAGTDREDQVAIRATGVLARRISRADGA-AGTATTWRPRGTALITGGTGALGGHVA 1210 Query: 1200 GYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAA 1259 +L G HVVL RR V V DVAD + ++ V A Sbjct: 1211 RWLVGQGVEHVVLLGRRGSDAPQAAALRDELTAAGARVTVAACDVADRDQLHEVVRKVRA 1270 Query: 1260 ELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTS 1319 + + +VHAAG T LS + E R A K GA HL R+DLD FV S Sbjct: 1271 DGAEIRVVVHAAGLGLTGALSEVRPEEFRRTMAAKALGALHLDALFG--RSDLDAFVLFS 1328 Query: 1320 SIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAA-GMADAESRARLEQR 1378 SIA +WG GQ+AY AANAFLD LA R RG+TA SV +G WA GMA+ ++ +L +R Sbjct: 1329 SIAGIWGSGGQSAYAAANAFLDALARHRRGRGLTATSVAWGAWAGDGMAEGDAAVQLARR 1388 Query: 1379 GVRTLSPAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXX 1437 G+ T+ AL+ + ++ VA +DWSRF Y E+ Sbjct: 1389 GITTMPVDRALSALRQILDRDETTATVADVDWSRFARTYLTVRDSRLFDEIAEAREAQAG 1448 Query: 1438 XXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLG 1496 L +L + + + +R A AEV +I ++ F DLG Sbjct: 1449 EPADDGKGAGDTPLTGRLRSLDEAAQHHALLDVVRTAAAEVLGHTGPTDIHEDRAFRDLG 1508 Query: 1497 MDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTA 1556 DSL AVE+R R+ G +P TL+ DHP A +L E+ G S A Sbjct: 1509 CDSLTAVEVRDRLRAATGLRLPATLLFDHPTPRVLAAHLRTELFGAPTAAVPALPSPAGA 1568 Query: 1557 -RTDDPIAVVAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPG 1613 DDPIA+V +SCR+PG PE W L+A G D + + P +R WD+ + DPD PG Sbjct: 1569 PMDDDPIAIVGMSCRYPGDVRSPEDLWRLVATGDDTLTDFPTNRGWDLSALFHDDPDRPG 1628 Query: 1614 KTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSR 1673 +Y EFFGI+PREA+ ++PQQRL+LE WE LERA AP LR S Sbjct: 1629 TSYATTGSFLHDVDEFDAEFFGINPREALAMDPQQRLLLEVTWEALERAHIAPESLRASP 1688 Query: 1674 TGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSS 1733 TGVF G +Y LLS I E + TGNA + +SGR+A+ G EGPAV VDTACSS Sbjct: 1689 TGVFVGTNGQDYVSLLSGAGI-AAEGYLATGNAASVVSGRLAYVFGLEGPAVTVDTACSS 1747 Query: 1734 ALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYV 1793 +LVA+H A Q+L+SG+C LA+AGGV V+ +P V SR R L+P GRCK F A ADG Sbjct: 1748 SLVALHMAVQSLRSGECSLAVAGGVTVMSTPGAFVEFSRQRGLAPDGRCKPFAAGADGTG 1807 Query: 1794 RSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARA 1853 EG GVL+L+RLS AV +G RV V+ S+VNQDGAS+GLT PNG +QQR+I L+ A Sbjct: 1808 WGEGAGVLLLERLSAAVANGHRVLGVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALSNA 1867 Query: 1854 GLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGA 1913 GL DVD +EAHGTGT LGDPIE Q PL +GSVK+NIGHT++A+G Sbjct: 1868 GLGPGDVDVVEAHGTGTSLGDPIEAQALLATYGQDRVEGRPLWLGSVKSNIGHTQAAAGV 1927 Query: 1914 AGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGF 1973 AG+IK+V++++HG+LP++LH + PSPH+ W A VR++ E VPW+ GR RRAGVSSFG Sbjct: 1928 AGVIKMVMAMRHGLLPETLHVDEPSPHVDWSAGEVRLLTESVPWRAEGRPRRAGVSSFGV 1987 Query: 1974 TGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDD 2033 +GTNAHV++EEAP P +S R L A R + Sbjct: 1988 SGTNAHVILEEAP----------AVAPLPEPPADHSGPVPWLVSGRGDAGLRGQAARLAE 2037 Query: 2034 WL-SATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEH 2092 ++ +D+A V VGR+ E RA +V + V + GVV G Sbjct: 2038 FVRGRDQDVDVAGVAAVL-VGRAVLENRAVVVGEGVADLVARLDVLAEGGSVDGVVCGSP 2096 Query: 2093 VHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRE 2152 V +A LFTGQGSQ+ GM EL+ VFA V + +LP PL VLF + Sbjct: 2097 V-GGKSAVLFTGQGSQFAGMGVELYGRFGVFAGVVDEVCAVADGLLPEPLRPVLFG-EGG 2154 Query: 2153 TADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGAR 2212 L+ T FAQ L A+E+GL R+ + DV++GHSVG+ +AA +GV SL D R Sbjct: 2155 RGGLIDRTVFAQVGLVALEVGLWRVLVECGVRADVLVGHSVGEVSAAVASGVLSLADAVR 2214 Query: 2213 LMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEE 2271 L+ RGR+ +P GG MV+V A E V + V V A N P + VL+G + Sbjct: 2215 LVCVRGRLMEEVPAGGVMVSVAAPEEVVRERVVGVAGVWVAAVNAPGSVVLAGEEGAVRG 2274 Query: 2272 IVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTG 2331 +V+ EG+R WL SHAFH+ L+DPVL+ P +P+V TG V G Sbjct: 2275 VVDGLVAEGVRTRWLPVSHAFHTPLMDPVLEEFSREIAGLAFEAPRIPVVSTVTGEV-AG 2333 Query: 2332 QTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRA 2391 A YW H+R+PV+FA++V LG V E+GPQP L+ AA+ V + A Sbjct: 2334 AGFGSAAYWVEHARRPVRFADAVGVARGLGVRVWAEVGPQPALS-AALDVREGEVVA--- 2389 Query: 2392 VASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPR--RPVELPTYPFQRRRFWPKAS 2449 + LR+ + L+ +V H D A PR V+LPTY FQRRR+WP S Sbjct: 2390 -SFLRRDRDQATSLLTGLSRLHV--HGVDVAWDSWLPRGTDSVDLPTYAFQRRRYWPGGS 2446 Query: 2450 SIAVDGGTAASG-------ILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGA 2502 A G + G +LG+ +A G ++T RLSV +QPWLADH + GTV++PG Sbjct: 2447 VGASTGSLSGVGLSGADHRLLGAQVTVADGAAVFTGRLSVSTQPWLADHAVSGTVLLPGT 2506 Query: 2503 TYA---AMALAAVGTPARLKDVFFYEPIIL-PEKASREVQLTLHPADGGSVLSFQIHSRP 2558 + A A VG+P ++ ++ P++L + VQ+ + D + I+SRP Sbjct: 2507 AFVDFMAHAGRRVGSP-QVGELTLQAPLVLAADGPGVAVQVVVDVPDEHGRRTVAIYSRP 2565 Query: 2559 YGERGADWSLNAEGTVDTAGSDPDAA-ADEQSDPVD---EVIERLERMRPQDLFETFADL 2614 + G DW+ + G + A DA A E SD + M +D++ ++ Sbjct: 2566 DNDTG-DWTRHGAGILTEAPQATDATEATETSDAPGASWDWPRAAAEMSGEDVYAGLSEA 2624 Query: 2615 ELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXX 2674 +GP + G LK +W DGE DI L + +HP L+D Sbjct: 2625 GFDYGPVFRG-LKQVW-QDGE---DIYAEVVLPDDPAGFVLHPALLDAALHALAADSG-- 2677 Query: 2675 XXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALG 2734 G + LP + V + P R R R D LE VD G + Sbjct: 2678 ----TGPGEAGLPFAFTGVRV--HRPGASTLRVRLRRQEPDG----VSLEAVDTAGHLVA 2727 Query: 2735 GIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSA-DDAVGTWLIAGFDELAAK 2793 I + V R A L G +L+ L W +P P A ++A G E+ + Sbjct: 2728 SI-DSLVFRPVSHADLAAPGAADGDVLH-LRW--IPLPERAQEEAPGEAPEEAPGEVPVE 2783 Query: 2794 VPGCVPIDRNTDLQVLG-------EVLSQAHARGAGFS---GVVWRCATPGRKXXXXXXX 2843 PG P+ D++ G ++++ + A AG + VV C P Sbjct: 2784 APGAEPVRNPADVRQYGGHVHAVPDIVAASAAVRAGAAEPHWVVLPCRAPDEGTVPERAR 2843 Query: 2844 XXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHGVAC-ESGEPVDPVQAALWGFGRT 2902 +L V A L ++T VA ES VD A +WG R+ Sbjct: 2844 VLTVW------VLGQVQAFLAAPEMAGRRLVVLTRGAVAADESDRGVDVSAAGVWGLVRS 2897 Query: 2903 TINEEPALHCRLVDCDGSSEAVD--XXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSG 2960 +E P RLV D +E D P++ R G L RL G Sbjct: 2898 AQSEHPD---RLVLLDVDTEVGDDEWPAVLSALSAAPLPQLVRRSGTLSTPRLEAAGDGG 2954 Query: 2961 HLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPD-------EGYVQVRVEAAGLNFRDVL 3013 LT P G ++L P G L L VP+P EG V+V V AAGLNFRDVL Sbjct: 2955 DLTAPPQGHWLLTPGSGGTSAELAL----VPQPSNADEPLGEGLVRVAVRAAGLNFRDVL 3010 Query: 3014 NVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIP 3073 LG+YPG IGG+ AG VT++G GV+G +G RV G + +FA A+ + +P Sbjct: 3011 ISLGMYPG-AASIGGEGAGVVTEVGPGVTGTAVGDRVMGLLPDSFADTSAADARMVVRMP 3069 Query: 3074 DGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFA 3132 + EAA++P LT R A D A L G++VL+HA +GGVG+AA+Q+A+ GAEVFA Sbjct: 3070 EDWTFQEAASVPIVFLTARYALGDLAGLCAGERVLVHAGAGGVGMAAVQLARHLGAEVFA 3129 Query: 3133 TASTFKRSTLRRLGV--KYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKA 3190 TA K LR LGV +V SR F L T GAGVDVVLNSL + FV+A+L+ Sbjct: 3130 TAHPSKWGALRELGVAEDHVASSRDLGFRAAFLEVTGGAGVDVVLNSL-AGEFVDASLEL 3188 Query: 3191 TAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARG 3250 +GGRF E+ K D+ + A + Y L EP RI D+L+E+ G Sbjct: 3189 LPRGGRFIEMGKTDV---REAASLPSGVRYRTFDLTE---PEPTRIGDMLSELLTLFRDG 3242 Query: 3251 EWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHT 3310 + LP + + A +AF ++ ARH GK+ D + LITGG G +G Sbjct: 3243 DLRLLPLTSWDVRRAPAAFGHVRLARHTGKV--VLNVPAPLDLDGTVLITGGTGTLGALV 3300 Query: 3311 AAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARI 3369 A +L G ++L RR P + E + + AAD+ + D+LA++ Sbjct: 3301 AEHLITAHGVRHLLLAGRRGPQAPGAEELVERLREYGADVRVVAADLAHRDEAVDVLAQV 3360 Query: 3370 RAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXX 3429 + PL G+ H AG++DD +L + P+R +A KA A H Sbjct: 3361 GTD-HPLTGVVHAAGIVDDGVLGSLTPDRVERVMAAKADAAWHLHELTRDADLAMFTLFS 3419 Query: 3430 XXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMAS---SEAATAN 3486 PGQANYA AN LD L RRA+GL A +++G W + S ++A A Sbjct: 3420 SASGVLGSPGQANYAAANTFLDALAEHRRARGLAAQSLSWGLWARRSAISGHLADADLAR 3479 Query: 3487 ITAQGLIPL-------------DPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSAR 3533 + G++PL D HA+ ++A G L A+ L Sbjct: 3480 VARSGMLPLGDEHGLRLMDGARDRGGRAHAVPVLLAPGHRHTHPLLAH-------LEGPS 3532 Query: 3534 PPILDLVLPSAAGEATGDSELLKQLMEIPIPQR-AGFVTEFLQREVQNFLRLASPPA--- 3589 P D S AGE + +PI +R G E +R + +R S A Sbjct: 3533 LPARDATRGSGAGEPS-----------VPIAERLRGLSAEEQRRTLLTLVREQSAAALGH 3581 Query: 3590 -------ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 A F +LG DSL +E+RNRL + G T+ AT VFD+PT G LA++L Sbjct: 3582 ESADAIGAHKPFKELGFDSLTGVEVRNRLGAVTG--VTLRATVVFDFPTPGALADHL 3636 Score = 632 bits (1631), Expect = e-178 Identities = 385/899 (42%), Positives = 513/899 (57%), Gaps = 24/899 (2%) Query: 1561 PIAVVAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTR 1618 PIA+V +SCRFPG PE W+ +A G DAI P+DR WD+D + D D G + T Sbjct: 41 PIAIVGMSCRFPGDVRSPEDLWDFVAAGGDAIAGFPKDRGWDLDTLFATDADGAGTSSTA 100 Query: 1619 XXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFT 1678 FFGISPREA+ ++PQQRL+LE WE +ERAG S LR S TGVF Sbjct: 101 AGGFVYDAGEFDAGFFGISPREALAMDPQQRLVLECSWEAIERAGIDVSTLRNSSTGVFL 160 Query: 1679 GVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAV 1738 G +A Y + + + E +F+TGNA + +SGR+A+ G EGPAV VDTACSS+LVA+ Sbjct: 161 GASAQNYG-TFADQGGEGSEGYFLTGNAASVVSGRLAYVFGLEGPAVTVDTACSSSLVAL 219 Query: 1739 HQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGC 1798 H A QAL++G+C LA+AGGV V+ +P V SR R L+P GRCK F A ADG EG Sbjct: 220 HLAAQALRAGECGLAVAGGVAVMSTPGAFVEFSRQRGLAPDGRCKPFAAGADGTGWGEGA 279 Query: 1799 GVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGA 1858 GVL+L+RLSDAV +G +V AV+ S+VNQDGAS+GLT PNG +QQR+I L+ AGL Sbjct: 280 GVLLLERLSDAVANGHQVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALSNAGLGTG 339 Query: 1859 DVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIK 1918 +VD +EAHGTGT LGDPIE Q PL +GSVK+NIGHT++A+G AG+IK Sbjct: 340 EVDVVEAHGTGTKLGDPIEAQALLATYGQDRPEGRPLWLGSVKSNIGHTQAAAGVAGVIK 399 Query: 1919 VVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNA 1978 +V++++HG+LP++LH + PSPH+ W A VR++ E VPW +GR RRAGVSSFG +GTNA Sbjct: 400 MVMAMRHGLLPETLHVDEPSPHVDWSAGEVRLLTEAVPWPADGRQRRAGVSSFGVSGTNA 459 Query: 1979 HVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSA- 2037 HV++EEAP P +S R L A R +++ Sbjct: 460 HVILEEAP----------AVEPAPEPTVVVSGPVPWLVSGRGDAGLRGQAARLAEFVQGR 509 Query: 2038 TPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPT 2097 +D+A V A +GR+ E RA +V + V GVV G V Sbjct: 510 DQDVDVAGVA-AALMGRAVLENRAVVVGEGVADLVARLDVLAGGGLVDGVVCGSPV-GGK 567 Query: 2098 TAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLL 2157 +A LFTGQGSQ+ GM L+ VFA V + +LP PL VLF + L+ Sbjct: 568 SAVLFTGQGSQFAGMGAGLYGRFGVFAGVVDEVCAVADGLLPEPLRPVLFG-EGGRGGLI 626 Query: 2158 QHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAER 2217 T FAQ L A+E+GL R+ + DV++GHSVG+ +AA +GV SL D RL+ R Sbjct: 627 DRTVFAQVGLVALEVGLWRVLVECGVRADVLVGHSVGEVSAAVASGVLSLADAVRLVCVR 686 Query: 2218 GRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERF 2276 GR+ +P GG MV+V A E V V V A N P + VL+G + +V+ Sbjct: 687 GRLMEEVPAGGVMVSVAAPEEVVRGRVVGVAGVWVAAVNAPGSVVLAGEEGAVRGVVDGL 746 Query: 2277 EDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLD 2336 EG+R WL SHAFH+ L+DPVL+ P +P+V TG V G Sbjct: 747 VAEGVRTRWLPVSHAFHTPLMDPVLEEFSREIAGLSFQEPRIPVVSTVTGEV-AGAGFGS 805 Query: 2337 AQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLR 2396 A YW H+R+PV+FA++V LG V E+GPQP L+ AA+ V + A + LR Sbjct: 806 AGYWVEHARRPVRFADAVGVARGLGVRVWAEVGPQPALS-AALDVREGEVVA----SFLR 860 Query: 2397 KGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDG 2455 + + L+ +V G + + VE+PTY FQRRR+W + S+ +V G Sbjct: 861 RDRDQATSLLTGLSRLHVHGVDVAWDQWVSRTGPLVEVPTYAFQRRRYWLEGSARSVVG 919 Score = 151 bits (381), Expect = 2e-33 Identities = 112/367 (30%), Positives = 165/367 (44%), Gaps = 18/367 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G H A +L G +VL RR D A+ + R+ A DV Sbjct: 1197 LITGGTGALGGHVARWLVGQGVEHVVLLGRRGSDAPQAAALRDELTAAGARVTVAACDVA 1256 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D Q+ +++ ++RA+ + + H AG+ LS PE FR T+A KA GA H Sbjct: 1257 DRDQLHEVVRKVRADGAEIRVVVHAAGLGLTGALSEVRPEEFRRTMAAKALGALHLDALF 1316 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQ+ YA ANA LD L RR +GL AT + +G W GM Sbjct: 1317 GRSDLDAFVLFSSIAGIWGSGGQSAYAAANAFLDALARHRRGRGLTATSVAWGAWAGDGM 1376 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP-I 3536 A +AA + +G+ + AL AL +++ ATV +W R A+ + R + Sbjct: 1377 AEGDAAV-QLARRGITTMPVDRALSALRQILDRDETTATVADVDWSRFARTYLTVRDSRL 1435 Query: 3537 LDLVL---------PSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 D + P+ G+ GD+ L +L + + + + ++ L P Sbjct: 1436 FDEIAEAREAQAGEPADDGKGAGDTPLTGRLRSLDEAAQHHALLDVVRTAAAEVLGHTGP 1495 Query: 3588 PAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL-- 3643 F DLG DSL A+E+R+RL + G + AT +FD+PT LA +L +L Sbjct: 1496 TDIHEDRAFRDLGCDSLTAVEVRDRLRAATG--LRLPATLLFDHPTPRVLAAHLRTELFG 1553 Query: 3644 -PDAEAP 3649 P A P Sbjct: 1554 APTAAVP 1560 >tr|A4F5C6|A4F5C6_SORCE Tax_Id=56 (spiG)SubName: Full=Polyketide synthase;[Sorangium cellulosum] Length = 5331 Score = 1885 bits (4882), Expect = 0.0 Identities = 1333/3741 (35%), Positives = 1855/3741 (49%), Gaps = 186/3741 (4%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAG 73 AI+G R PG A E + L G +A++ +P RWD + +DPDP+ GK R A Sbjct: 37 AIVGLGLRLPGGAVDPESLGSFLERGVDAVAPIPASRWDADAIYDPDPNAIGKSYVRSAA 96 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 +D V FDA FFG+S RE + +DPQHR+L+ETAW+A+E +GI P SL ++ TGVFVG Sbjct: 97 LLDRVDLFDAAFFGISPREAKHVDPQHRLLLETAWQALEEAGIVPASLKDTKTGVFVGAG 156 Query: 134 THDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQ 193 +Y + D + +AY +GTS + AAGR+++ LG+QGPA++VDTACSSSLVA+H Sbjct: 157 ASEYATLRGDA---EKADAYATMGTSTSFAAGRLAFTLGVQGPALSVDTACSSSLVALHL 213 Query: 194 ACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGV 253 ACQ+LR +ECDLALA G V+ +P + S LAPDGR KTF A+ADGY RGEG V Sbjct: 214 ACQSLRRDECDLALAAGVQVMASPEPFVLISRTRALAPDGRSKTFSASADGYGRGEGVVV 273 Query: 254 VVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADV 313 + ++RL DA +G + AVIRGSAIN DG S G+T PNG +QQ+V+ AL+ AGL P DV Sbjct: 274 LALERLRDARANGHPVLAVIRGSAINHDGTSSGITAPNGSSQQKVLRAALEDAGLAPTDV 333 Query: 314 GYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXX 373 +E HGTGTSLGDP+E A V G R E PLL+G+ KTNIGHLE Sbjct: 334 DVVECHGTGTSLGDPVEVHAVAAVYGEDRPAERPLLLGAVKTNIGHLEAAAGLAGVAKVV 393 Query: 374 XXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR--NGKPRIAGVSSFGFAGTNA 431 L TLP L+ P+PH+ WE LP+ VV W R +G PR AGVS+FGF+GTNA Sbjct: 394 AALRRATLPPTLHTHPPNPHVAWETLPLRVVDAAQRWDRRADGAPRRAGVSAFGFSGTNA 453 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQARLA 489 HVI+EEAPA E S LP +SA+T AL A L A P+ LA Sbjct: 454 HVIVEEAPAPEGATAPEAERACAHASPLPVVISAKTEGALRGQAARLHAHLAARPELALA 513 Query: 490 DVSHTAGTARAHLEQRAALVVNSRESAIELLGAL---ADDRPAPGLVRGESHEAPKTAWL 546 D++ + T R+H E RA +V + RE+ + L L A+ P PG + G + A L Sbjct: 514 DIAASLATTRSHFEHRAVVVAHDREAVLTALDGLARGANASPPPGTLVGGDAPKGRLAIL 573 Query: 547 FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLR 606 FTGQG Q M L+ PVF + + + L++PL +V+F + L Sbjct: 574 FTGQGGQRAAMGHGLYQAFPVFRDALDAVCAHLDRDLDRPLREVLFAPK--GSELARLLD 631 Query: 607 HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERG 666 T + Q ALFA+E+ L RL ++WG PD ++GHSVG+ +AA VAGV +ED L++ R Sbjct: 632 ETVFTQTALFALEVALFRLVEAWGVAPDALLGHSVGEITAAHVAGVLSLEDACALVSARA 691 Query: 667 RLFGSLPA-----------GGRMAAVFTA-PERAERLTDEYPSLSVAAYNG-ANTVLSGP 713 RL +LPA G +AAV A E R T +AA NG ++TV++G Sbjct: 692 RLMQALPARDAAMVAIAASEGEVAAVIAARGEGGARAT-------IAAINGPSSTVVAGD 744 Query: 714 AKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRT 773 + A A G + L SHAFHS +D +LD F A+ L + P+ ++ N T Sbjct: 745 RDAVLDVAARFEALGRKTSRLRVSHAFHSHHMDGMLDAFRRVAEGLTFHPPRIPIVSNVT 804 Query: 774 GSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAW-PD 832 G G YW RHAR V FA + TL LE+GP VL+A +A D Sbjct: 805 GQRAGDGELCSADYWVRHARSAVRFADGLGTLHTERVSTFLELGPHGVLSALGQSALEAD 864 Query: 833 PATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLPTYPFEHRQ 891 + + +LR D + A+ A +A GH D+RAF P AR++ LPTY F+ + Sbjct: 865 APSRALFVPTLRADRDDGDALVTALGALHARGHRVDWRAFFAPVGARRVPLPTYAFQRER 924 Query: 892 FWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKL 951 FW D R+ A P + R +E+ ++ L + + E+ + L Sbjct: 925 FWVDDAPPEPRE-----AAQPAPAEARFWRAIEESNVDMLRDALGVASEGEERAALSTLL 979 Query: 952 AARHNQQRSTHV---DPDARYEIRWDXXXXXXXXXXXXXDWILV---GDDTAAVLEFADA 1005 A +R V RY + W W++V G V A Sbjct: 980 PALSAWRRKGQVLGLVDTWRYRVAW-RPIAATSRGDASGTWLVVRAAGAYDGVVESVVRA 1038 Query: 1006 LTAGGHRHQIVALPGSDADEAQLVDTLRAASAG----ELYVVHIAAGDGAAAPMRDLLRV 1061 L G + L A+L LR A AG + + DG + + Sbjct: 1039 LEGRGGDVVTLGLGADACARAELAARLREAVAGRGALRGVLSFVGLDDGPSTSQPAVPAG 1098 Query: 1062 QHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELP 1120 RTL L +A D+ L + +WL +R V+ D +V P Q+ WG R +LE P Sbjct: 1099 LARTL----TLVQALGDSALDARVWLFSRGAVSVSRADAIVNPAQAATWGLARVVSLEHP 1154 Query: 1121 HIWGGLADL------SGA--DTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEP 1172 GG DL SGA L+A + GED++ALR + ++A RLVR Sbjct: 1155 ERLGGAVDLASSLGASGALDAAAIDHLVAALGGALAGEDELALRPEGLFARRLVR--APL 1212 Query: 1173 SDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQ 1232 + P P T LVTGG GA+G VA A GA H+VLTSRR P Sbjct: 1213 GEAPRPRAPRGTVLVTGGTGALGAHVARLFAQRGAKHLVLTSRRGPDAPSARALHDELTA 1272 Query: 1233 YACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFA 1292 V + DV D + L + A+ PL+ +VHAAG + L L +D VF Sbjct: 1273 LGARVTIAACDVGDRAALEELFAAMPAD-APLSAVVHAAGVLDDGVLDALTPERLDAVFR 1331 Query: 1293 GKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGV 1352 K A HL E LT R DLD FV SS + V+G GQ +Y AANA+LD LA R RGV Sbjct: 1332 AKALAARHLDE-LTRSR-DLDAFVLFSSASGVFGSAGQGSYAAANAYLDALAEARRARGV 1389 Query: 1353 TAVSVNFGPWA-AGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWS 1410 TA S+ +G WA GM + + L + G+ + P A A +A + V +A IDW+ Sbjct: 1390 TATSIAWGAWAGGGMLEDAVASDLRRSGLSPMRPEVATAALAHALDHDDDVVTIADIDWA 1449 Query: 1411 RFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNY 1470 RF P + R F+SEL L ++ + + L+ Sbjct: 1450 RFAPSFASVRERPFVSELPEAKRAQGALAANPARPDESALLTALRAQSDDDRLRHLVGLV 1509 Query: 1471 LRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSD 1530 L A + DA + GFFDLG+DSLMAVELR R+++ G +P T++ D P Sbjct: 1510 LGETAAVLGHADASRVDAHKGFFDLGLDSLMAVELRLRLQKATGIRLPSTIMFDQPSPER 1569 Query: 1531 AADYLLVEVL-GLGEQTNVRQASTVTARTD-DPIAVVAVSCRFPGAP-DPESFWELLAGG 1587 A +L + LGE+ +V A R D +P+A+V +S R PG D W+LL G Sbjct: 1570 VATFLRDALARTLGERGDVDAALVARTRHDGEPVAIVGLSLRLPGGTGDLAGLWDLLERG 1629 Query: 1588 VDAIREVPEDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQ 1647 VDA+ +P RWD YDPDPD GK+Y R FFGISPREA ++PQ Sbjct: 1630 VDAVGPIPASRWDAGAAYDPDPDAKGKSYVRSAALLDGVDLFDAAFFGISPREAKHVDPQ 1689 Query: 1648 QRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNAL 1707 RL+LE W+ LE AG P+ L+GS+TGVF G A++YA LL +S D+ + + G A Sbjct: 1690 HRLLLEAAWQALEEAGVVPASLKGSKTGVFVGAGASDYA-LLQRDS-DEDDAYAAMGTAS 1747 Query: 1708 NAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTV 1767 +GR+AF LG EGPA++VDTACSS+LVA+H ACQ+L+ G+CDLALA G V+ SP Sbjct: 1748 AFAAGRLAFTLGLEGPALSVDTACSSSLVALHLACQSLRQGECDLALAAGAQVMASPEAF 1807 Query: 1768 VAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQ 1827 V SR R L+P GR KTF A+ADG+ R EG VL L+RLSDA +G V AV+ S++N Sbjct: 1808 VLLSRTRALAPDGRSKTFSANADGFGRGEGVVVLALERLSDARANGRPVLAVVRGSAMNH 1867 Query: 1828 DGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXX 1887 DGASSG+TVPNG AQQ+++ L AGL+ A++D +E HGTGT LGDPIEV Sbjct: 1868 DGASSGITVPNGTAQQKVLRGALDDAGLAPAEIDVVECHGTGTALGDPIEVNALAAVYGE 1927 Query: 1888 XXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALP 1947 PLL+G++KTNIGH E+A+G AG+ KVV +L++G LP +LH +PH+ WD LP Sbjct: 1928 GRPADRPLLVGAIKTNIGHLEAAAGLAGVAKVVAALRNGALPATLHTSPLNPHLAWDELP 1987 Query: 1948 VRVIDEPVPW--QTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXX 2005 VRVID PW + RRAGVS+FG +GTNAHV++EEAP Sbjct: 1988 VRVIDGACPWLRRAEDTPRRAGVSAFGLSGTNAHVIIEEAP------GDADASASAATAE 2041 Query: 2006 GTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVV 2065 LSA++ AL ARR ++A L +AD+ + RSHF+ RAA+V Sbjct: 2042 AAPGRELPFVLSAKTEAALRAQARRLHAHVAANGELSLADLGFSLATTRSHFDERAAVVA 2101 Query: 2066 DSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQ 2125 V V ++F GQGSQ+P MA L D++PVF + Sbjct: 2102 SDRDALLHGLDALARGEPAPETVAASTVSSGKLVFVFPGQGSQWPEMASALLDSEPVFRE 2161 Query: 2126 TVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEP 2185 + C A+A + LL VL R+ L QP LFAV + LA +W++ +EP Sbjct: 2162 QLLACEGALAPHVDWSLLTVL-RHGRDGDASLDRVDVVQPVLFAVMVALAAMWRATGVEP 2220 Query: 2186 DVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQ-VA 2244 D V+GHS G+ AAA VAG SL+D A+++A R R L G M A+ A +++ + Sbjct: 2221 DAVVGHSQGEIAAAYVAGALSLEDAAKVVALRARAITRLAGRGAMAAIELPASELDRHLD 2280 Query: 2245 GEFPRVSVGAYNGPNTVL-SGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDX 2303 G R+ + A N P T L +G ++ +V I + +A HSE + + + Sbjct: 2281 GLDGRIGIAAINSPRTTLVAGDVAAVDALVGTLSAAQIFARKVRVDYASHSEHVAAIENE 2340 Query: 2304 XXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCS 2363 LP+ TG L GQ LDA +W R+ RQ V+F ++ R + A Sbjct: 2341 LLRDLGGISPRASALPIYSAVTGEKLDGQA-LDAAHWYRNLRQTVRFEDATRALLADQHR 2399 Query: 2364 VLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAA 2423 +E+ P PVL+ A + + + V +LR+ R + +LA + GHR ++A Sbjct: 2400 FFVEVSPHPVLSLALRETIBDAGLSAAVVPTLRRDDGHRARFLLSLAELHARGHRVVWSA 2459 Query: 2424 VH--RQPRRPVELPTYPFQRRRFW---PKASSIAVDGGTAAS--GILGSGKDLASGD-TI 2475 + +PRR V LPTY FQR RFW P+A + G A++ +L + LA D + Sbjct: 2460 LFDAHRPRR-VPLPTYAFQRERFWLDAPRARADVAAAGLASAEHPLLKASVALAGSDGYL 2518 Query: 2476 YTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEK 2532 +T RLS+ PWLA H ++G ++PG + +ALAA VG A + ++ P+ LP Sbjct: 2519 FTGRLSLAEHPWLAGHAVFGEPILPGTAFLDLALAAAHRVGLDA-VDELTLEAPLALPAT 2577 Query: 2533 ASREVQLTLHPADGGSVLSFQIHSRPYGERGAD--WSLNAEGTVD--TAGSDPDAAADEQ 2588 VQ+ L D S +H+RP + G D W+ +A G + AG+ D A Sbjct: 2578 GGVVVQMALGATDDDGRRSLTVHARP-DDAGDDAAWTRHATGALGPRAAGASLDVGAFPP 2636 Query: 2589 SDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAE 2648 D + L++ A LA+G + G L+++W E ++++ A Sbjct: 2637 GDATP--------LATAGLYDRLARAGLAYGTDFQG-LRAVWKRGDELFAEVVLSEATAR 2687 Query: 2649 QLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRAR 2708 +HP +D + E+ + +P + V+L + R Sbjct: 2688 DAARFGLHPAALD--AALHALAAEVLDGGEKA--HVAMPFSWSGVSLHAVGASTLHVRIA 2743 Query: 2709 WHRSALDSETQVFELEFVDLGGRALGGIREFTVK--RAPREALLRGLGGDATRLLYTLGW 2766 R D+ L D G+ + + ++ A R + G + W Sbjct: 2744 --RKGGDT----VALAIADAAGQKVASVDALALRPASATRVRGAKPRTGPVHDAXLRVDW 2797 Query: 2767 HEVPPPPSADDAVGTWLIAGFD-ELAAKVPGC-VPIDRNTDLQVLGEVLSQAHARGAGFS 2824 E+P P A W I G D LA+ + + R+ D G + GA Sbjct: 2798 IELPSGPEG-AAPRAWAILGSDARLASALEAAGAHVTRHRD---PGAWIDAIRGGGAPEV 2853 Query: 2825 GVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACE 2884 V C T + L+A+ A L ++TE VA Sbjct: 2854 VAVLACTT----RPDAPSGALAATHGAAADALAALQAWLAEERLASCALVVLTERAVATR 2909 Query: 2885 SGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVD-----XXXXXXXXPGIQE 2938 E V D V A +WG R E P LVD D ++ E Sbjct: 2910 PDEDVLDLVHAPVWGLVRAAQVENPDRALILVDVDADDASLPALPALVAAAVARAADASE 2969 Query: 2939 PEIAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLT--ETDVPEPDEG 2996 P++A+R+G+ L RL L P + L +G +++L L E EG Sbjct: 2970 PQLALREGRRLVPRLGRLGGDDALVPPSAAAYRLHVAAKGTLESLALVPHEEATRPLAEG 3029 Query: 2997 YVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQG 3056 ++V V AAGLNFRD L+ LG+YPGDPGP+G + AG V ++G GV+ L G RV G + Sbjct: 3030 QIRVAVRAAGLNFRDALDALGMYPGDPGPLGAEGAGVVLEVGPGVTELAPGDRVMGLLSA 3089 Query: 3057 AFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGV 3115 AF + ++ IP G+ VEAA+IP LT D +L+PG++VL+HAA+GGV Sbjct: 3090 AFGPIALADHRMVSRIPAGLSFVEAASIPVVFLTAYYGLVDLGRLRPGERVLVHAAAGGV 3149 Query: 3116 GLAAIQMAQQSGAEVFATASTFKRSTLRRLGV--KYVYDSRTTDFADQILADTNGAGVDV 3173 G+AA+Q+A+ GAEVFATAS K +TLR LG+ ++ SR+ DF + G GVDV Sbjct: 3150 GIAAVQLARHLGAEVFATASPPKWATLRALGLDDDHIASSRSGDFEAHFRRTSGGRGVDV 3209 Query: 3174 VLNSLTSAGFVEATLK--ATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFT 3231 VL+SL + V+A+L+ A A GRF E+ K D+ +A + P +AY L Sbjct: 3210 VLDSL-ARELVDASLRLVALAPDGRFVEMGKSDVRDPLAVAASHPSVAYRAFDLAE---A 3265 Query: 3232 EPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXX 3291 P+RI+ +L E+ RG P + A AFR + QAR +GK+ Sbjct: 3266 GPERIQAMLAELVALFERGVLRVPPITPCDLRRAPQAFRALAQARLVGKVVLTIPRALDP 3325 Query: 3292 XXDRSYLITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIH 3350 S L+TGG G +G A +L Q G +VL+SRR P + E + Sbjct: 3326 RG--SVLVTGGTGTLGALVARHLVQRHGVRSLVLSSRRGPAAPGADDLRRELEAAGASVA 3383 Query: 3351 TYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGA 3410 A D GD + LLA I A+ PL + H AG LDD +L++ PER R+ ++ K A Sbjct: 3384 IVACDAGDRLALERLLAGIPAD-RPLTAVVHAAGTLDDGVLTSLTPERLRSVMSAKVDAA 3442 Query: 3411 SHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFG 3470 +H PGQANYA AN LD L +RR++GL A +++G Sbjct: 3443 AHLDELTRPLDLSAFVLFASLSGVLGSPGQANYAAANTFLDALAHQRRSRGLPAVSLDWG 3502 Query: 3471 PWGQGGMASSEAATANITAQ---GLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAK 3527 W + ++ ++ GL PL L +A+ A ++ A + A Sbjct: 3503 YWAERTGLTAHLGDTDLQRMARGGLRPLTTDDGLALFDAALAH--VDAALVAAPFDPVAL 3560 Query: 3528 VLGSARPPILDLVLPSA-----AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL 3582 + P + LV A A A + L ++L + +R + + ++ E+ L Sbjct: 3561 RAHAVAPILRGLVRAGAARRKLANNAASAAPLAQRLAGLAPKERERAMIDVVRPEIGVVL 3620 Query: 3583 RLASPPAASSRFLD-------LGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGL 3635 L PP SR LD LG DSLMA+ELRNRL + G + + AT +FDYPT L Sbjct: 3621 GL--PP---SRHLDGDRPLKELGLDSLMAVELRNRLAAIVGTR--LPATLLFDYPTPTAL 3673 Query: 3636 AEY----LVGQLPDAEAPETA 3652 A + LVG+ A AP A Sbjct: 3674 ARFLATALVGRGDAAAAPSAA 3694 Score = 865 bits (2236), Expect = 0.0 Identities = 585/1565 (37%), Positives = 782/1565 (49%), Gaps = 61/1565 (3%) Query: 13 SFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTR 70 + AI+ A RFPG + E+ + LLR+G +AIS P++R WD++ D R Sbjct: 3705 AIAIVAMACRFPGGVLTPEDLFRLLREGGDAISAFPENRGWDLDALSDG--------AAR 3756 Query: 71 RAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFV 130 + GF+ D FDA FFG+S RE +DPQ R+L+E W A+E +GI P SL S +GVFV Sbjct: 3757 QGGFLHDADLFDAEFFGISPRETLALDPQQRLLLEMTWEALERAGIIPASLHGSKSGVFV 3816 Query: 131 GLATHDYLGMA----SDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSS 186 G+ DY+ S + Y+ G++++ A+GRI+Y LGL+GPA++VDTACSS Sbjct: 3817 GVFGSDYVARLLHGPSGAQAMESLRGYIGTGSASSVASGRIAYALGLEGPAISVDTACSS 3876 Query: 187 SLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYV 246 SLVA+H AC A+R EC LALAGG V+ TP FS H APDGRCK+F A A+G Sbjct: 3877 SLVALHLACHAIRRGECSLALAGGVTVMATPGIFGEFSAQHAGAPDGRCKSFSADANGAG 3936 Query: 247 RGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRA 306 EG G+V+++RL DA ++G + A++RGSA+NQDG S GLT PNG AQ+RVI DAL A Sbjct: 3937 WSEGAGIVLLERLSDARKNGHPVLAIVRGSAVNQDGKSQGLTAPNGPAQERVIRDALASA 3996 Query: 307 GLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXX 366 GL PADV +EAHGTGT+LGDPIEA+A GA A E PL +GS K+N+GH + Sbjct: 3997 GLAPADVDAVEAHGTGTTLGDPIEARALFATYGAAHAKERPLWLGSLKSNLGHTQAAAGI 4056 Query: 367 XXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGF 426 L++ LP+ L+ +PS HI W I ++ E VPW+ G PR A VSSFG Sbjct: 4057 GGVIKMVLALQSGVLPRTLHAASPSQHIDWSSGAIRLLTEEVPWKPGGSPRRAAVSSFGI 4116 Query: 427 AGTNAHVILEEAP--AVGTPATTEPVEDPRRYSV-LPLSARTPEALVRLAGEYRDWLRAH 483 +GTNAHV+LEEAP A G EP P V + LSA++ AL AG+ L H Sbjct: 4117 SGTNAHVVLEEAPRAAAGDDQAAEPARAPLAPPVPVLLSAKSDAALRAQAGKLHAHLAEH 4176 Query: 484 PQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKT 543 L DV+ + T R+H E+RAA+V + R + + L ALA+ R G V GE+ K Sbjct: 4177 EDVALVDVAASLATTRSHFERRAAVVADDRAALLSALAALAEGRAGAGTVAGEALPPGKV 4236 Query: 544 AWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTES 603 A++F GQGSQ+P MAR L + P F + C A+A ++ LL V+ DE Sbjct: 4237 AFVFPGQGSQWPSMARALLASSPAFRAEIEACERALAPHVDWSLLAVL-GGDE--AHAAP 4293 Query: 604 PLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIA 663 L QP LFAV + LA W++ G PD VVGHS G+ +AA VAG +ED AR++A Sbjct: 4294 MLERVDVVQPVLFAVMIALAATWRAAGVTPDAVVGHSQGEIAAAYVAGALSLEDAARVVA 4353 Query: 664 ERGRLFGSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGANTVL-SGPAKDLESAV 721 R R L G MAAV T + RL L++AA N + L SG ++ V Sbjct: 4354 LRSRAITKLAGRGAMAAVELTTADLEARLAPFGGRLAIAAINSPHAALVSGDPDAIDELV 4413 Query: 722 ATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRST 781 A L + + +A HSA ++ I + R L TG L Sbjct: 4414 AELSGAQLFARKVRVDYASHSAHVEAIERTLLEALDGIAPRPATVPLYSAVTGERLD-GE 4472 Query: 782 RLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLA 841 L A+W R+ R V F + R L D R +E+ P PVLT A Sbjct: 4473 ALGAAHWYRNLRHTVRFEHATRALLDDGHRFFVEVSPHPVLTVALRDTIDASGHDAVACA 4532 Query: 842 SLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDA-RKLDLPTYPFEHRQFWFSDNRAI 900 SLR D + ++A + G D+RAF P A R + LPTY F+ +FW +A Sbjct: 4533 SLRRDEGDLARFNLSLAELHTRGLAVDWRAFFAPFAPRTVALPTYAFQRERFWLDAPKA- 4591 Query: 901 DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALID-GETVDEQTLRVLNKLAARHNQQR 959 + +P + +EDG + + +D G+ L L A + R Sbjct: 4592 ----SGVIPAAASPAEARFWSAVEDGDVATVTDALDVGDDERRAALATLLPTLATWRRAR 4647 Query: 960 STHVDPDA-RYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLE--FADALTAGGHRHQIV 1016 DA RY + W W++V + A L A AL A G R +V Sbjct: 4648 RAQSTIDAWRYRVAW-RALTAPPKGDIAGTWLVVAPEVAGALADGVARALEARGARGVLV 4706 Query: 1017 ALPGSDADEAQLVDTLRAASAGELY--VVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFR 1074 + DA L LRA + G+ V+ AA D AP+ + + G L + Sbjct: 4707 PVDAEDAARTPLAGRLRAVAGGQAIRGVISFAALDERPAPLEPSVPLGLAVSLG---LVQ 4763 Query: 1075 AANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADL---S 1130 A DA + +P+WLVTR V ++ V P Q+ WG GR ALE P WGGL DL S Sbjct: 4764 ALGDAAIDAPLWLVTRGAVAVGASERVTRPLQAMTWGLGRVVALEHPERWGGLVDLGEES 4823 Query: 1131 GADTEWPR------LIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT 1184 D R +A + + RD EDQ+ALR Y RLVR + + P Sbjct: 4824 APDANGARDANVHDRLANLVARRDDEDQLALRAAGTYVRRLVRAPHDGARPPAFAPRGAA 4883 Query: 1185 YLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADV 1244 LVTGG GA+G VA +LA GA H+VL SRR V + DV Sbjct: 4884 -LVTGGTGALGAHVARWLARIGAEHIVLASRRGAAAPGAAALAEELSALGARVTLAACDV 4942 Query: 1245 ADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEA 1304 AD VA L+ V A + + HA G + P++ + E+ A K GA HL + Sbjct: 4943 ADREAVAALVRDVEAGGATVRAVFHAGGAMHEAPVAAMRVEELADAIAAKARGAQHLHDV 5002 Query: 1305 LTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA- 1363 + LD FV SS A VWGG Q AY AANAFLD LA R G+ A S+ +G WA Sbjct: 5003 FA--QRPLDAFVLFSSGAGVWGGGRQGAYAAANAFLDALAEARRADGLAATSIAWGAWAG 5060 Query: 1364 AGMADAESRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRR 1422 GM ++ RL+ RGV + P A+A +A + VA +DW+RF P + A R Sbjct: 5061 GGMLATDAERRLKHRGVAPMDPELAVAALAHALDHAETCLAVADVDWARFAPSFASARPR 5120 Query: 1423 AFLSELE------SELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVA 1476 L EL L L L P +R + +R A Sbjct: 5121 PLLDELAEARSALDALREPPDDARTAAGPEPASTLRTTLAALPEGERHRHLLALVRTETA 5180 Query: 1477 EVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYL 1535 V DA + GFFDLG+DSLM+VELRRR+++ G +P TL DHP S A + Sbjct: 5181 AVLGHADASRVEPNRGFFDLGLDSLMSVELRRRVQRATGIKLPATLAFDHPTPSALASKV 5240 Query: 1536 LVEVL 1540 L ++ Sbjct: 5241 LAAIV 5245 Score = 723 bits (1867), Expect = 0.0 Identities = 481/1289 (37%), Positives = 673/1289 (52%), Gaps = 47/1289 (3%) Query: 1186 LVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADV 1244 LVTGG G +G VA +L HG +VL+SRR P E V ++ D Sbjct: 3330 LVTGGTGTLGALVARHLVQRHGVRSLVLSSRRGPAAPGADDLRRELEAAGASVAIVACDA 3389 Query: 1245 ADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEA 1304 D + RL+ + A+ P L +VHAAG + L+ L + V + KV A HL E Sbjct: 3390 GDRLALERLLAGIPADRP-LTAVVHAAGTLDDGVLTSLTPERLRSVMSAKVDAAAHLDEL 3448 Query: 1305 LTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA- 1363 L DL FV +S++ V G GQ Y AAN FLD LA + R RG+ AVS+++G WA Sbjct: 3449 TRPL--DLSAFVLFASLSGVLGSPGQANYAAANTFLDALAHQRRSRGLPAVSLDWGYWAE 3506 Query: 1364 -----AGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQ 1418 A + D + + R+ + G+R L+ + LA +A +VA + F P+ + Sbjct: 3507 RTGLTAHLGDTDLQ-RMARGGLRPLTTDDGLALFDAALAHVDAALVA----APFDPVALR 3561 Query: 1419 AGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEV 1478 A A L + L ++L ++R+ + + +R + V Sbjct: 3562 A--HAVAPILRGLVRAGAARRKLANNAASAAPLAQRLAGLAPKERERAMIDVVRPEIGVV 3619 Query: 1479 TRVDADEIRD-EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLV 1537 + D + +LG+DSLMAVELR R+ VG +P TL+ D+P + A +L Sbjct: 3620 LGLPPSRHLDGDRPLKELGLDSLMAVELRNRLAAIVGTRLPATLLFDYPTPTALARFLAT 3679 Query: 1538 EVLGLGEQTNVRQASTVTAR--TDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREV 1594 ++G G+ A+ + +DD IA+VA++CRFPG PE + LL G DAI Sbjct: 3680 ALVGRGDAAAAPSAARAASAGASDDAIAIVAMACRFPGGVLTPEDLFRLLREGGDAISAF 3739 Query: 1595 PEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLE 1653 PE+R WD+D D R EFFGISPRE + ++PQQRL+LE Sbjct: 3740 PENRGWDLDALSDGA--------ARQGGFLHDADLFDAEFFGISPRETLALDPQQRLLLE 3791 Query: 1654 TVWEGLERAGYAPSDLRGSRTGVFTGVAANEY-AHLL----SAESIDKIEPHFITGNALN 1708 WE LERAG P+ L GS++GVF GV ++Y A LL A++++ + + TG+A + Sbjct: 3792 MTWEALERAGIIPASLHGSKSGVFVGVFGSDYVARLLHGPSGAQAMESLRGYIGTGSASS 3851 Query: 1709 AISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVV 1768 SGR+A+ALG EGPA++VDTACSS+LVA+H AC A++ G+C LALAGGV V+ +P Sbjct: 3852 VASGRIAYALGLEGPAISVDTACSSSLVALHLACHAIRRGECSLALAGGVTVMATPGIFG 3911 Query: 1769 AASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQD 1828 S +P GRCK+F A A+G SEG G+++L+RLSDA ++G V A++ S+VNQD Sbjct: 3912 EFSAQHAGAPDGRCKSFSADANGAGWSEGAGIVLLERLSDARKNGHPVLAIVRGSAVNQD 3971 Query: 1829 GASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXX 1888 G S GLT PNG AQ+R+I LA AGL+ ADVD +EAHGTGT LGDPIE + Sbjct: 3972 GKSQGLTAPNGPAQERVIRDALASAGLAPADVDAVEAHGTGTTLGDPIEARALFATYGAA 4031 Query: 1889 XXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPV 1948 PL +GS+K+N+GHT++A+G G+IK+VL+LQ GVLP++LH +PS HI W + + Sbjct: 4032 HAKERPLWLGSLKSNLGHTQAAAGIGGVIKMVLALQSGVLPRTLHAASPSQHIDWSSGAI 4091 Query: 1949 RVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTD 2008 R++ E VPW+ G RRA VSSFG +GTNAHV++EEAP Sbjct: 4092 RLLTEEVPWKPGGSPRRAAVSSFGISGTNAHVVLEEAPRAAAGDDQAAEPARAPLA---- 4147 Query: 2009 DSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSV 2068 P + LSA+S AL A + L+ + + DV + RSHFE RAA+V D Sbjct: 4148 -PPVPVLLSAKSDAALRAQAGKLHAHLAEHEDVALVDVAASLATTRSHFERRAAVVADDR 4206 Query: 2069 XXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVR 2128 AG V GE + A++F GQGSQ+P MAR L + P F + Sbjct: 4207 AALLSALAALAEGRAGAGTVAGEALPPGKVAFVFPGQGSQWPSMARALLASSPAFRAEIE 4266 Query: 2129 QCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVV 2188 C A+A + LL VL + A +L+ QP LFAV + LA W++ + PD V Sbjct: 4267 ACERALAPHVDWSLLAVLGGDEAHAAPMLERVDVVQPVLFAVMIALAATWRAAGVTPDAV 4326 Query: 2189 LGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF- 2247 +GHS G+ AAA VAG SL+D AR++A R R L G M AV +E F Sbjct: 4327 VGHSQGEIAAAYVAGALSLEDAARVVALRSRAITKLAGRGAMAAVELTTADLEARLAPFG 4386 Query: 2248 PRVSVGAYNGPNTVL-SGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXX 2306 R+++ A N P+ L SG + ++E+V + + +A HS ++ + Sbjct: 4387 GRLAIAAINSPHAALVSGDPDAIDELVAELSGAQLFARKVRVDYASHSAHVEAIERTLLE 4446 Query: 2307 XXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM 2366 T+PL TG L G+ L A +W R+ R V+F + R + G + Sbjct: 4447 ALDGIAPRPATVPLYSAVTGERLDGEA-LGAAHWYRNLRHTVRFEHATRALLDDGHRFFV 4505 Query: 2367 EIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR 2426 E+ P PVLT A A ASLR+ D + +LA + G D+ A Sbjct: 4506 EVSPHPVLTVALRDTIDASGHDAVACASLRRDEGDLARFNLSLAELHTRGLAVDWRAFFA 4565 Query: 2427 Q-PRRPVELPTYPFQRRRFW---PKASSI 2451 R V LPTY FQR RFW PKAS + Sbjct: 4566 PFAPRTVALPTYAFQRERFWLDAPKASGV 4594 Score = 649 bits (1673), Expect = 0.0 Identities = 393/923 (42%), Positives = 519/923 (56%), Gaps = 29/923 (3%) Query: 1543 GEQTNVRQA----STVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPED 1597 G T++RQA S + + +PIA+V + R P GA DPES L GVDA+ +P Sbjct: 13 GLTTSLRQARRRLSDIEGKQREPIAIVGLGLRLPGGAVDPESLGSFLERGVDAVAPIPAS 72 Query: 1598 RWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWE 1657 RWD D YDPDP+ GK+Y R FFGISPREA ++PQ RL+LET W+ Sbjct: 73 RWDADAIYDPDPNAIGKSYVRSAALLDRVDLFDAAFFGISPREAKHVDPQHRLLLETAWQ 132 Query: 1658 GLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFA 1717 LE AG P+ L+ ++TGVF G A+EYA L +K + + G + + +GR+AF Sbjct: 133 ALEEAGIVPASLKDTKTGVFVGAGASEYATLRG--DAEKADAYATMGTSTSFAAGRLAFT 190 Query: 1718 LGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLS 1777 LG +GPA++VDTACSS+LVA+H ACQ+L+ +CDLALA GV V+ SP V SR R L+ Sbjct: 191 LGVQGPALSVDTACSSSLVALHLACQSLRRDECDLALAAGVQVMASPEPFVLISRTRALA 250 Query: 1778 PVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVP 1837 P GR KTF ASADGY R EG VL L+RL DA +G V AVI S++N DG SSG+T P Sbjct: 251 PDGRSKTFSASADGYGRGEGVVVLALERLRDARANGHPVLAVIRGSAINHDGTSSGITAP 310 Query: 1838 NGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLM 1897 NG +QQ+++ A L AGL+ DVD +E HGTGT LGDP+EV PLL+ Sbjct: 311 NGSSQQKVLRAALEDAGLAPTDVDVVECHGTGTSLGDPVEVHAVAAVYGEDRPAERPLLL 370 Query: 1898 GSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPW 1957 G+VKTNIGH E+A+G AG+ KVV +L+ LP +LH P+PH+ W+ LP+RV+D W Sbjct: 371 GAVKTNIGHLEAAAGLAGVAKVVAALRRATLPPTLHTHPPNPHVAWETLPLRVVDAAQRW 430 Query: 1958 --QTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLA 2015 + +G RRAGVS+FGF+GTNAHV+VEEAP SP + Sbjct: 431 DRRADGAPRRAGVSAFGFSGTNAHVIVEEAP------APEGATAPEAERACAHASPLPVV 484 Query: 2016 LSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVV---DSVXXXX 2072 +SA++ AL A R L+A P L +AD+ + RSHFE+RA +V ++V Sbjct: 485 ISAKTEGALRGQAARLHAHLAARPELALADIAASLATTRSHFEHRAVVVAHDREAVLTAL 544 Query: 2073 XXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAE 2132 P G + G + A LFTGQG Q M L+ PVF + Sbjct: 545 DGLARGANASPPPGTLVGGDAPKGRLAILFTGQGGQRAAMGHGLYQAFPVFRDALDAVCA 604 Query: 2133 AVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGH 2191 + L RPL +VLFA E A LL T F Q ALFA+E+ L RL ++W + PD +LGH Sbjct: 605 HLDRDLDRPLREVLFAPKGSELARLLDETVFTQTALFALEVALFRLVEAWGVAPDALLGH 664 Query: 2192 SVGQYAAACVAGVFSLDDGARLMAERGRMFGSLP-EGGRMVAVFADAEHVEQV---AGE- 2246 SVG+ AA VAGV SL+D L++ R R+ +LP MVA+ A V V GE Sbjct: 665 SVGEITAAHVAGVLSLEDACALVSARARLMQALPARDAAMVAIAASEGEVAAVIAARGEG 724 Query: 2247 FPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXX 2305 R ++ A NGP +TV++G + + ++ RFE G + + L SHAFHS +D +LD Sbjct: 725 GARATIAAINGPSSTVVAGDRDAVLDVAARFEALGRKTSRLRVSHAFHSHHMDGMLDAFR 784 Query: 2306 XXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVL 2365 P +P+V N TG A YW RH+R V+FA+ + T+ S Sbjct: 785 RVAEGLTFHPPRIPIVSNVTGQRAGDGELCSADYWVRHARSAVRFADGLGTLHTERVSTF 844 Query: 2366 MEIGPQPVLTGAAVQVWPEHMAAPRA--VASLRKGVADRRQIADALASAYVGGHRPDFAA 2423 +E+GP VL+ A Q E A RA V +LR D + AL + + GHR D+ A Sbjct: 845 LELGPHGVLS-ALGQSALEADAPSRALFVPTLRADRDDGDALVTALGALHARGHRVDWRA 903 Query: 2424 VHRQ-PRRPVELPTYPFQRRRFW 2445 R V LPTY FQR RFW Sbjct: 904 FFAPVGARRVPLPTYAFQRERFW 926 Score = 627 bits (1618), Expect = e-177 Identities = 373/904 (41%), Positives = 504/904 (55%), Gaps = 23/904 (2%) Query: 6 HPIEPTPSFAIIGYAARFPGAAS-AEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTP 64 H EP AI+G + R PG W LL G +A+ +P RWD +DPDP Sbjct: 1598 HDGEPV---AIVGLSLRLPGGTGDLAGLWDLLERGVDAVGPIPASRWDAGAAYDPDPDAK 1654 Query: 65 GKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANS 124 GK R A +D V FDA FFG+S RE + +DPQHR+L+E AW+A+E +G+ P SL S Sbjct: 1655 GKSYVRSAALLDGVDLFDAAFFGISPREAKHVDPQHRLLLEAAWQALEEAGVVPASLKGS 1714 Query: 125 NTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTAC 184 TGVFVG DY + D E +AY A+GT++A AAGR+++ LGL+GPA++VDTAC Sbjct: 1715 KTGVFVGAGASDYALLQRDS---DEDDAYAAMGTASAFAAGRLAFTLGLEGPALSVDTAC 1771 Query: 185 SSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADG 244 SSSLVA+H ACQ+LR ECDLALA GA V+ +P + S LAPDGR KTF A ADG Sbjct: 1772 SSSLVALHLACQSLRQGECDLALAAGAQVMASPEAFVLLSRTRALAPDGRSKTFSANADG 1831 Query: 245 YVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALK 304 + RGEG V+ ++RL DA +G + AV+RGSA+N DGAS G+TVPNG AQQ+V+ AL Sbjct: 1832 FGRGEGVVVLALERLSDARANGRPVLAVVRGSAMNHDGASSGITVPNGTAQQKVLRGALD 1891 Query: 305 RAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXX 364 AGL PA++ +E HGTGT+LGDPIE A V G GR + PLL+G+ KTNIGHLE Sbjct: 1892 DAGLAPAEIDVVECHGTGTALGDPIEVNALAAVYGEGRPADRPLLVGAIKTNIGHLEAAA 1951 Query: 365 XXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGK--PRIAGVS 422 L N LP L+ +PH+ W+ LP+ V+ PW R + PR AGVS Sbjct: 1952 GLAGVAKVVAALRNGALPATLHTSPLNPHLAWDELPVRVIDGACPWLRRAEDTPRRAGVS 2011 Query: 423 SFGFAGTNAHVILEEAP----AVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRD 478 +FG +GTNAHVI+EEAP A + AT E P R LSA+T AL A Sbjct: 2012 AFGLSGTNAHVIIEEAPGDADASASAATAEAA--PGRELPFVLSAKTEAALRAQARRLHA 2069 Query: 479 WLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESH 538 + A+ + LAD+ + T R+H ++RAA+V + R++ + L ALA PAP V + Sbjct: 2070 HVAANGELSLADLGFSLATTRSHFDERAAVVASDRDALLHGLDALARGEPAPETVAASTV 2129 Query: 539 EAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELD 598 + K ++F GQGSQ+P MA L D+EPVF E + C A+A ++ LL V+ D Sbjct: 2130 SSGKLVFVFPGQGSQWPEMASALLDSEPVFREQLLACEGALAPHVDWSLLTVL--RHGRD 2187 Query: 599 GDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDG 658 GD + L QP LFAV + LA +W++ G EPD VVGHS G+ +AA VAG +ED Sbjct: 2188 GD--ASLDRVDVVQPVLFAVMVALAAMWRATGVEPDAVVGHSQGEIAAAYVAGALSLEDA 2245 Query: 659 ARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPS-LSVAAYNGANTVL-SGPAKD 716 A+++A R R L G MAA+ +R D + +AA N T L +G Sbjct: 2246 AKVVALRARAITRLAGRGAMAAIELPASELDRHLDGLDGRIGIAAINSPRTTLVAGDVAA 2305 Query: 717 LESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSA 776 +++ V TL A + + +A HS + I ++ + R + TG Sbjct: 2306 VDALVGTLSAAQIFARKVRVDYASHSEHVAAIENELLRDLGGISPRASALPIYSAVTGEK 2365 Query: 777 LGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATT 836 L LD A+W R+ RQ V F + R L R +E+ P PVL+ D + Sbjct: 2366 LD-GQALDAAHWYRNLRQTVRFEDATRALLADQHRFFVEVSPHPVLSLALRETIBDAGLS 2424 Query: 837 PQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFS 895 V+ +LR + ++A +A GH + A F R++ LPTY F+ +FW Sbjct: 2425 AAVVPTLRRDDGHRARFLLSLAELHARGHRVVWSALFDAHRPRRVPLPTYAFQRERFWLD 2484 Query: 896 DNRA 899 RA Sbjct: 2485 APRA 2488 Score = 154 bits (390), Expect = 2e-34 Identities = 118/364 (32%), Positives = 162/364 (44%), Gaps = 21/364 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA++GA IVL SRR A+ E R+ A DV Sbjct: 4884 LVTGGTGALGAHVARWLARIGAEHIVLASRRGAAAPGAAALAEELSALGARVTLAACDVA 4943 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D VA L+ + A + + H G + +A ++A E +A KA GA H Sbjct: 4944 DREAVAALVRDVEAGGATVRAVFHAGGAMHEAPVAAMRVEELADAIAAKARGAQHLHDVF 5003 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 Q YA ANA LD L RRA GL AT I +G W GGM Sbjct: 5004 AQRPLDAFVLFSSGAGVWGGGRQGAYAAANAFLDALAEARRADGLAATSIAWGAWAGGGM 5063 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP-PI 3536 +++ A + +G+ P+DP A+ ALA + + V +W R A SARP P+ Sbjct: 5064 LATD-AERRLKHRGVAPMDPELAVAALAHALDHAETCLAVADVDWARFAPSFASARPRPL 5122 Query: 3537 LDLVL------------PSAAGEATGD---SELLKQLMEIPIPQRAGFVTEFLQREVQNF 3581 LD + P A A G S L L +P +R + ++ E Sbjct: 5123 LDELAEARSALDALREPPDDARTAAGPEPASTLRTTLAALPEGERHRHLLALVRTETAAV 5182 Query: 3582 L--RLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 L AS + F DLG DSLM++ELR R+ G K + AT FD+PT LA + Sbjct: 5183 LGHADASRVEPNRGFFDLGLDSLMSVELRRRVQRATGIK--LPATLAFDHPTPSALASKV 5240 Query: 3640 VGQL 3643 + + Sbjct: 5241 LAAI 5244 Score = 45.1 bits (105), Expect = 0.22 Identities = 54/205 (26%), Positives = 72/205 (35%), Gaps = 30/205 (14%) Query: 2762 YTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGC-------------VPIDRNTDLQV 2808 Y + W + PP D A GTWL+ + A G VP+D + Sbjct: 4658 YRVAWRALTAPPKGDIA-GTWLVVAPEVAGALADGVARALEARGARGVLVPVDAEDAART 4716 Query: 2809 LGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVK 2868 +A A G GV+ A R + L V A ++ Sbjct: 4717 PLAGRLRAVAGGQAIRGVISFAALDERPAPLEPSVPLG-----LAVSLGLVQALGDAAID 4771 Query: 2869 LPGGLWIVTEHGVACESGEPVD-PVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXX 2927 P LW+VT VA + E V P+QA WG GR E P LVD G A D Sbjct: 4772 AP--LWLVTRGAVAVGASERVTRPLQAMTWGLGRVVALEHPERWGGLVDL-GEESAPDAN 4828 Query: 2928 XXXXXXPGIQEPEIAVRQGKLLASR 2952 G ++ + R L+A R Sbjct: 4829 -------GARDANVHDRLANLVARR 4846 >tr|Q6W5P9|Q6W5P9_9ACTO Tax_Id=206662 (fscB)SubName: Full=FscB;[Streptomyces sp. FR-008] Length = 5541 Score = 1858 bits (4813), Expect = 0.0 Identities = 1319/3725 (35%), Positives = 1843/3725 (49%), Gaps = 172/3725 (4%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 A++ A R+PG + ++ W L RDG +AIS P +R WD++ F PDP+ G TR Sbjct: 37 AVVAMACRYPGGVRTPQDLWELARDGVDAISAFPANRGWDLDHLFHPDPAHHGTTYTREG 96 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FD FFG+S RE MDPQ R+L+ET+W A+E +GI P +LA S TGVFVG Sbjct: 97 GFLHDAGEFDPAFFGISPREALAMDPQQRLLLETSWEALERAGILPDTLAGSTTGVFVGT 156 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 DY G + E+ ++ G + A A+GR+SY G +GPAV VDTACSSSLVA+H Sbjct: 157 GHGDYDGASRGR--QKEVAGHLLTGNTVAVASGRLSYTYGFEGPAVTVDTACSSSLVALH 214 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A ++LR EC LALAGGA V+ TP FS LA DGRCK F A ADG EG G Sbjct: 215 LAVRSLRQGECSLALAGGATVMSTPKMFTEFSRQQGLAADGRCKPFAAGADGTAWSEGVG 274 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++++RL DA R+G I AVIRGSAINQDGAS GLT PNG +QQR+I AL AGL + Sbjct: 275 LILLERLSDAQRNGHEILAVIRGSAINQDGASNGLTAPNGPSQQRLIRQALIDAGLTSGE 334 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT+LGDPIEAQA G R PLL+GS K+N GH + Sbjct: 335 VDVVEAHGTGTTLGDPIEAQALLNTYGQDRGDAHPLLLGSLKSNTGHTQAASGVAGVIKM 394 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + TLPK L+ + P+PH W +E++ E+ W G+PR A VSSFG +GTNAH Sbjct: 395 VQAMRHGTLPKSLHVDAPTPHADWATGGVELLTESTTWPETGRPRRAAVSSFGVSGTNAH 454 Query: 433 VILEEAPAVGTPATTEPVEDP---------RRYSVLPLS-ARTPEALVRLAGEYRDWLRA 482 +ILE+AP TP EP +P R + V S A E RLA R Sbjct: 455 LILEQAPEDQTPRAEEPGTEPSADDSADTVRSWMVSGKSRAAVGEQAARLAASVRA---- 510 Query: 483 HPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE-AP 541 A + DV+H ++R +++RA +V + RE + L ALA P+ +V G + E A Sbjct: 511 -SDASVLDVAHALVSSRVAMDRRAVVVGSDREELLAGLDALAAGEPSVRVVEGTAGEGAG 569 Query: 542 KTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDT 601 A++F GQGSQ+ GMA EL + PVFA V +CA A+ E LLDV+ + ++G Sbjct: 570 DVAFVFPGQGSQWVGMAVELLGSSPVFAGRVAECAAALEPFTEWSLLDVL---NGVEG-- 624 Query: 602 ESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARL 661 + L QP L+AV + LA +W++ G EP V+GHS G+ +AA VAG +EDGAR+ Sbjct: 625 AASLERVDVVQPVLWAVMVSLAEVWRAQGVEPGAVIGHSQGEIAAAVVAGGLSLEDGARV 684 Query: 662 IAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPS-LSVAAYNG-ANTVLSGPAKDLES 719 +A R R +L G M +V + L + +SVAA NG ++ V+SG A+ L+ Sbjct: 685 VALRSRALRALSGLGGMVSVARNVDEVRGLLAGWEGRISVAAVNGPSSVVVSGDAEALDE 744 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 VA A GVR + +A HSA ++ I ++ + R +G + Sbjct: 745 FVAACDASGVRARRVAVDYASHSAHVERIEEELAGLLAPVAPRSCDVPFYSTLSGGVID- 803 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 + LD YW R+ R VEF R L RV +E+ PV+ D + V Sbjct: 804 TAGLDAGYWYRNLRGTVEFEAGTRALLADGFRVFVEVSAHPVVATGVQETIEDASVQAGV 863 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDNR 898 + +LR + ++ A+A G D+ + R +DLPTYPF +W + Sbjct: 864 VGTLRRDEGGLERFALSLGEAWALGAEVDWETHYAGTRPRHVDLPTYPFRRDWYWLTPAE 923 Query: 899 AIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQ 958 + A+A + P +E G + L+++++ D + L A ++ Sbjct: 924 S------AAAAATGDPADGDFWSAVESGDLTRLSSVLEVTGDDVEAFGTLLPALASWRRR 977 Query: 959 RSTHVDPDA-RYEIRWDXXXXXXXXXXXXXDWILVGD---DTAAVLEFADALTAGGHRHQ 1014 R+ D R+ + W LV D V ALT G R + Sbjct: 978 RTLRSTLDTWRHRVTWTALTGADDAVPAGRWPALVPAGHADDPWVHAVLGALTGRGLRVE 1037 Query: 1015 IVALPGSDADEAQLV-------DTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLG 1067 L G D D A L DT + G V+ + A D P + R L Sbjct: 1038 RHDLTG-DEDTAALTALLTGTGDTEPDGAEGIAGVLSLLALDERPHPDHPAVP---RGLA 1093 Query: 1068 GLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGL 1126 + L A + E + +W +TR V D + P Q+ WGFGRA ALELP WGGL Sbjct: 1094 TAKELLHALSGTE--ASVWALTRGAVAVDSRDRLTSPVQAETWGFGRAVALELPDAWGGL 1151 Query: 1127 ADLSGADTEWPRLIARITSPRDG-EDQIALRGDAVYAPRLVRRT-GEPS-----DTPLPV 1179 ADL AD + R +AR+ + G EDQIA+R YA RL R EP+ D L V Sbjct: 1152 ADLP-ADPD-ARSLARLATLLGGPEDQIAVRSSGAYARRLARMPLPEPARVTDVDAELAV 1209 Query: 1180 R-----------EDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXX 1228 R + T L+TGG GA+G VA LA+ GA H+VLTSRR P Sbjct: 1210 RAADDDGIGGWGDHDTVLITGGTGALGAHVARSLAASGARHLVLTSRRGPGSPGAVGLVA 1269 Query: 1229 XXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVD 1288 E+ V V DVAD +ARL+ ++ A LP L G+VHAAG + L L + Sbjct: 1270 ELEELGARVTVADCDVADRDQLARLLDSLPAGLP-LTGVVHAAGVLDDGVLDALTLDRFE 1328 Query: 1289 RVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLR 1348 V K G HL E D D+ FV SSI V G GQ Y AANA+LD +A + R Sbjct: 1329 AVLRPKTLGTAHLHELTRD--HDVTLFVLFSSIVGVLGNAGQANYAAANAYLDAVAEQRR 1386 Query: 1349 ERGVTAVSVNFGPWA-AGMADAESRA-RLEQRGVRTLSPAEALAGMADVVA-GPVQGVVA 1405 G+ SV +GPWA AGMA A+ A R+ G+ + P A+A + VA G V Sbjct: 1387 AEGLPVTSVAWGPWADAGMATADVLADRMSHDGLAPMDPVTAVAALRAAVAEGVPHATVL 1446 Query: 1406 KIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTK--APVQQR 1463 +DW Y A A S L +L + + AP +Q Sbjct: 1447 DVDWRA----YGTAMTAARPSPLVGDLPEVRRALEAAAATAPDTHALRDRLRGLAPAEQD 1502 Query: 1464 KSLITNYLRNAVAEVTRVDADEIRD-EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLV 1522 + L+T+ +R VA R + E D F DLG DSL AVE+R RI +P TL+ Sbjct: 1503 R-LLTDLVRAEVATALRHSSPEAVDVNRAFKDLGFDSLTAVEVRNRITAATDVKLPTTLL 1561 Query: 1523 MDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTAR-TDDPIAVVAVSCRFPGA-PDPESF 1580 D+P + +L L LG++ V V+A TD+P+AVVA++CRFPG PE Sbjct: 1562 FDYPNTTAVVAHL--RTLLLGDERPVAAPVVVSAGVTDEPMAVVAMACRFPGGVTTPEEL 1619 Query: 1581 WELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPR 1639 W L+A VDA+ PEDR WD+D YDPDP+ G TY+R P FFGISPR Sbjct: 1620 WHLMAAEVDAVSTPPEDRGWDLDALYDPDPERHGTTYSREGGFIQDVAGFDPVFFGISPR 1679 Query: 1640 EAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEY-AHLLSAESIDKIE 1698 EA+ ++PQQRL+LET WE ERAG P LR S TGVF G +Y L A + +++ Sbjct: 1680 EALAMDPQQRLLLETSWETFERAGIDPGTLRNSATGVFVGSITTDYQVRLGGAAAQEQLA 1739 Query: 1699 PHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGV 1758 H +TGNA + SGR+++ GFEGPAV +DT CSS++VA+H A Q+L++G+C +ALAGGV Sbjct: 1740 GHLMTGNASSIASGRLSYTYGFEGPAVTMDTGCSSSMVALHLALQSLRTGECTMALAGGV 1799 Query: 1759 NVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCA 1818 V+ +P V SR R L+ GRCK F ADG +EG G+++L+RLSDA R+G V A Sbjct: 1800 TVMSTPEPYVEFSRQRGLAADGRCKAFAEGADGMGFAEGVGLVLLERLSDARRNGHPVLA 1859 Query: 1819 VIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEV 1878 V+ S++NQDGAS+GLT PNG +QQR+I LA AGL+ +VD +EAHGTGTPLGDPIE Sbjct: 1860 VVRGSALNQDGASNGLTAPNGPSQQRVIRQALANAGLAPGEVDVVEAHGTGTPLGDPIEA 1919 Query: 1879 QXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPS 1938 Q PLL+GS+K+NIGHT++A+G AG++K++L+++ G LP+SLH P+ Sbjct: 1920 QAILATYGQDRDPARPLLLGSLKSNIGHTQAAAGVAGMMKMILAMRQGTLPKSLHITRPT 1979 Query: 1939 PHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXX 1998 + W + VR++ E PW GR RRAGVSSFG +GTN H+++EEAP Sbjct: 1980 SVVDWSSGAVRLVTESTPWPETGRPRRAGVSSFGISGTNGHLILEEAPAPEPAEDEPADP 2039 Query: 1999 XXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFE 2058 + D+ + +S +S A+ E A R + T + DV H R + Sbjct: 2040 FTEPSADDSADTVRSWMVSGKSRAAVGEQAARLAASV-RTSDASVLDVAHALVSSRVAMD 2098 Query: 2059 YRAALV-VDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELF 2117 RA +V D +P V A++F GQGSQ+ GMA EL Sbjct: 2099 RRAVVVGRDGEELLAGLDALAAGEPSPRLVEGSVGDGSGKVAFVFPGQGSQWVGMAVELL 2158 Query: 2118 DTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARL 2177 + PVFA V +CA A+ LLDVL E A L+ QP L+AV + LA + Sbjct: 2159 GSSPVFAGRVAECAAALEPFTEWSLLDVLNGV--EGAASLERVDVVQPVLWAVMVSLAEV 2216 Query: 2178 WQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADA 2237 W++ +EP V+GHS G+ AAA VAG SL+DGAR++A R R +L G MV+V + Sbjct: 2217 WRAQGVEPGAVIGHSQGEIAAAVVAGGLSLEDGARVVALRSRALRALSGLGGMVSVARNV 2276 Query: 2238 EHVE-QVAGEFPRVSVGAYNGPNT-VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSE 2295 + V +AG R+SV A NGP++ V+SG E L+E V + G+R +A +A HS Sbjct: 2277 DEVRGLLAGWEGRISVAAVNGPSSVVVSGDAEALDEFVAACDASGVRARRVAVDYASHSA 2336 Query: 2296 LLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVR 2355 ++ + + +P +G V+ LDA YW R+ R V+F R Sbjct: 2337 HVERIEEELAGLLAPVAPRSCDVPFYSTLSGGVI-DTAGLDAGYWYRNLRGTVEFEAGTR 2395 Query: 2356 TVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVG 2415 + A G V +E+ PV+ + + V +LR+ + A +L A+ Sbjct: 2396 ALLADGFRVFVEVSAHPVVATGVQETIEDASVQAGVVGTLRRDEGGLERFALSLGEAWAL 2455 Query: 2416 GHRPDFAAVHRQPR-RPVELPTYPFQRRRFWPKASSIAVDGGTAA-----SGILGSGKDL 2469 G D+ + R R V+LPTY FQR+ +WP+ + + D +A +LG+ +L Sbjct: 2456 GAEVDWETHYAGTRPRHVDLPTYAFQRQHYWPRFAELGGDVSSAGLDSPDHPLLGASVEL 2515 Query: 2470 ASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA--VGTPARLKDVFFYEP 2526 A GD + T+R S+++ PWLADH + GTV+VPG + A V R++++ P Sbjct: 2516 AGGDGLVATARWSLRTHPWLADHAVSGTVIVPGTALVESVIRAGDVLGCGRIEELALQAP 2575 Query: 2527 IILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGAD---WSLNAEGTVDTAGSDPDA 2583 ++L E+ +VQ+ + D +H+R G GA W+L A+GT+ G+ Sbjct: 2576 VVLQERGEAQVQIGVGEPDASGRRPVTVHTRTTGPDGATEDLWTLRAQGTLTEPGA---P 2632 Query: 2584 AADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVG 2643 A D + + + +E A +GP + G +++ W + ++++ Sbjct: 2633 AVDRPEEFTSWPPPGATAVAAEGFYELLAGRGYEFGPVFQG-VRATWSRGEDLYAEVVLP 2691 Query: 2644 AELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRF 2703 ++ G +HP L+D +P + V L Sbjct: 2692 EQVRGDAGRFGIHPALLDAALHAAHLAPG-------SAGRTVVPFTWSGVCLHAAGATAL 2744 Query: 2704 YCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYT 2763 R R + D+ ++ D G + I V+ + L A L+ Sbjct: 2745 --RVRVSPAGQDA----ISVQLTDPTGAPVATIDALAVREIAPDTLDPSARA-ARDWLFR 2797 Query: 2764 LGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVL---GEVLSQAHARG 2820 L W V PP + A G W + G P P T L G + A G Sbjct: 2798 LDWTPVTPPAAVPAATG-WAVLG----TPADPVTAPDGSGTTLPAFATPGALAEHTEANG 2852 Query: 2821 AGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHG 2880 V+ + ++L+ V + L +VT Sbjct: 2853 HRPDAVLLFAGAAASGTAAAPDAEPGVPDAVLDDVLATVQSWLADETTEGVPLVVVTRGA 2912 Query: 2881 VACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEP 2939 V +P D AA+WG R+ ++ P LVD D D EP Sbjct: 2913 VPTGPADPAHDLPGAAVWGLVRSAQSQHPG-RLVLVDLDIHD---DSWLALPAALAAGEP 2968 Query: 2940 EIAVRQGKLLASRLLPWARSGHLTLPRG-GDFVLAPTERGAIDNLRLTET--DVPEPDEG 2996 ++A+RQG A RL+ S LT+P G G++ L E+G++D L L EP G Sbjct: 2969 QLALRQGAAYAPRLVRPRTSDALTVPEGTGNWRLDIPEKGSVDRLDLVAAPGTAEEPAAG 3028 Query: 2997 YVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQG 3056 V + V AAGLNFRDVLN LG+YPG +G + AG VT +G GV+G G RV G + G Sbjct: 3029 EVVIEVRAAGLNFRDVLNTLGMYPGPAVLLGAEAAGVVTAVGEGVTGFAPGDRVMGLVSG 3088 Query: 3057 AFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGV 3115 FA R A+ LAP+PDG +AA++P A LT D A L G+ VL+HAA+GGV Sbjct: 3089 GFAPRAVADARMLAPVPDGWTWAQAASVPVAFLTAYYGLRDLAHLDAGESVLVHAAAGGV 3148 Query: 3116 GLAAIQMAQQSGAEVFATASTFKRSTLRRLG--VKYVYDSRTTDFADQILADTNGAGVDV 3173 G+AA Q+A+ GAEV+ TA KR+ LR G ++ SRT F D+ + G GVDV Sbjct: 3149 GMAAAQLARHWGAEVYGTAGDHKRTLLRADGWDDAHLASSRTLAFEDRFRTTSGGRGVDV 3208 Query: 3174 VLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIA-YEIVALDTVMFTE 3232 VLNSL + +++A+L+ A GGR ++ K D+ Q+ P A Y+ L Sbjct: 3209 VLNSL-AGDYIDASLRLLAPGGRLVDMGKTDVRDPGQVLRDHPAAALYQAYELRE---AG 3264 Query: 3233 PDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXX 3292 DRI+++ ++S+ A G PLP + + AR AFR M QA+H GKI Sbjct: 3265 EDRIQEMFRDLSELFASGALRPLPTVTWDVRHAREAFRHMAQAKHYGKI--VLTLPRAWD 3322 Query: 3293 XDRSYLITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHT 3351 + + L+TGG G +G A +L + G +VLT RR PD + + Sbjct: 3323 PEGTVLVTGGAGVLGGILARHLVTRHGMRHLVLTGRRGPDTPGAGELAAELRELGAEVTL 3382 Query: 3352 YAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS 3411 A D D +A +LA + AE PL + H AGVLDD +L + P+R RT LAPKA A Sbjct: 3383 AACDAADADALAAVLAAVPAE-HPLTAVVHAAGVLDDGVLESLTPDRLRTVLAPKADAAR 3441 Query: 3412 HXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGP 3471 H GQANYA AN LD L +RRA GL T +++G Sbjct: 3442 HLHRLTRDLDLTDLVLFSAGAGVFGNAGQANYAAANTYLDALAHRRRADGLPTTSLSWGL 3501 Query: 3472 WGQGGMAS---SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKV 3528 W + + A + G++PL + + + ++ + + Sbjct: 3502 WADTSALTGQLDDTDLARVRRSGVLPLSAADGMVLFDAALTEQRPHLVPVRLETGQ-LRA 3560 Query: 3529 LGSARPPILDLVL------PSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL 3582 G PP+L + + AG ATG L +L R + + + L Sbjct: 3561 SGDEVPPLLRSLYRGPVRRTAEAGAATGTDGLRARLAGRSAEDRLSTLRDLVGAHAAAVL 3620 Query: 3583 RL--ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV 3640 P A F DLG DSL A+ELRNRL + G + AT VFD+PT+ LA +L Sbjct: 3621 GHDDTEPFHAGRAFRDLGFDSLTAVELRNRLSAATG--LRLPATLVFDHPTVAALAAHLD 3678 Query: 3641 GQLPD 3645 G+L D Sbjct: 3679 GELSD 3683 Score = 773 bits (1996), Expect = 0.0 Identities = 557/1521 (36%), Positives = 757/1521 (49%), Gaps = 90/1521 (5%) Query: 1184 TYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITA 1242 T LVTGG G +G +A +L + HG H+VLT RR P + +V + Sbjct: 3326 TVLVTGGAGVLGGILARHLVTRHGMRHLVLTGRRGPDTPGAGELAAELRELGAEVTLAAC 3385 Query: 1243 DVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLS 1302 D ADA +A ++ V AE PL +VHAAG + L L + V A K A HL Sbjct: 3386 DAADADALAAVLAAVPAE-HPLTAVVHAAGVLDDGVLESLTPDRLRTVLAPKADAARHLH 3444 Query: 1303 EALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW 1362 DL DL V S+ A V+G GQ Y AAN +LD LA R R G+ S+++G W Sbjct: 3445 RLTRDL--DLTDLVLFSAGAGVFGNAGQANYAAANTYLDALAHRRRADGLPTTSLSWGLW 3502 Query: 1363 A-----AGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQ 1417 A G D AR+ + GV LS A+ + + D + +P+ Sbjct: 3503 ADTSALTGQLDDTDLARVRRSGVLPLSAADGMV-LFDAALTEQR--------PHLVPVRL 3553 Query: 1418 QAGR-RAFLSE----LESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYL- 1471 + G+ RA E L S L +L + R S + + + Sbjct: 3554 ETGQLRASGDEVPPLLRSLYRGPVRRTAEAGAATGTDGLRARLAGRSAEDRLSTLRDLVG 3613 Query: 1472 RNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDA 1531 +A A + D + F DLG DSL AVELR R+ G +P TLV DHP ++ Sbjct: 3614 AHAAAVLGHDDTEPFHAGRAFRDLGFDSLTAVELRNRLSAATGLRLPATLVFDHPTVAAL 3673 Query: 1532 ADYLLVEVLGLGEQTNVRQA---STVTARTDDPIAVVAVSCRFPG-APDPESFWELLAGG 1587 A +L E L G + A + DDP A+V ++CR PG PE W LLA G Sbjct: 3674 AAHLDGE-LSDGTPAALPAAPAPAPAAPGDDDPFAIVGMACRLPGDIHSPEDLWRLLADG 3732 Query: 1588 VDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEP 1646 DA+ P+DR WD+ YD P+ G + TR +FFGISPREA+ ++P Sbjct: 3733 ADAVAPFPDDRGWDLARLYDSVPEGQGSSRTREGGFLHDAADFDADFFGISPREALAMDP 3792 Query: 1647 QQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNA 1706 QQRL+LET WE ERAG P +RGSRTGVF G+++++Y ++ D+I + GNA Sbjct: 3793 QQRLLLETAWETFERAGIDPRSVRGSRTGVFAGLSSSDYLKRVTHVP-DEIAGYVNNGNA 3851 Query: 1707 LNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVT 1766 + +SGRV++ LG EGPAV VDTACSS+LVA+H A QAL+ G+C +ALAGGV V+ SP Sbjct: 3852 NSIVSGRVSYTLGLEGPAVTVDTACSSSLVALHMALQALRRGECTMALAGGVTVMSSPEI 3911 Query: 1767 VVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVN 1826 +V SR R L+ GRCK F +ADG SEG G+++++RLSDA R+G +V AV+ S+VN Sbjct: 3912 IVDFSRQRGLAADGRCKPFAEAADGTGFSEGVGLILVERLSDARRNGHQVLAVVRGSAVN 3971 Query: 1827 QDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXX 1886 QDGAS+GL+ PNG AQQR+I LA AG+ A+VD +EAHGTGT LGDPIE Q Sbjct: 3972 QDGASNGLSAPNGPAQQRVIRQALADAGVGAAEVDVVEAHGTGTRLGDPIEAQALLATYG 4031 Query: 1887 XXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDAL 1946 PL +GSVK+N+GHT++A+G AG++K+VL+L+H +LP+SLH + P+PH+ W Sbjct: 4032 RDRDGGHPLFLGSVKSNLGHTQAAAGVAGVMKMVLALRHRLLPESLHIDAPTPHVDWADS 4091 Query: 1947 PVRVIDEPVPWQTNG--RVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXX 2004 VR++ E W G R RRA VSSFG +G PP Sbjct: 4092 GVRLLTEATAWPEAGASRPRRAAVSSFGISGHQRPRHPGGGPPPPPARTAASRSPPAPDA 4151 Query: 2005 XGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALV 2064 T +P LSARS AL A+ L A PG D AD+ HT R+ E R A+V Sbjct: 4152 AETRPAPLPWVLSARSEAALRGQAKALLTHLDAHPGTDPADIAHTLVTRRAQLEKR-AVV 4210 Query: 2065 VDSVXXXXXXXXXXXXXXTPAGVV----RGEHVHRPTTAWLFTGQGSQYPGMARELFDTQ 2120 V S +PA V RG R T +F GQGSQ+ GM EL D Sbjct: 4211 VGSATGDFRAGLAALAEGSPAAHVVTGGRGAGRDR-RTVLVFPGQGSQWAGMGAELLDAS 4269 Query: 2121 PVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQS 2180 P FA V C EA+A + L VL E A L QP +AV + LA +W++ Sbjct: 4270 PAFADRVAACEEALAPYVDWSLTAVL--RQEEGAPALDRVDVVQPVTWAVMVALAEVWRA 4327 Query: 2181 WAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFG-SLPEGGRMVAVFADAEH 2239 + P VLGHS G+ AAA VAG SL D AR++A R R L G MVAV A + Sbjct: 4328 HGLRPAAVLGHSQGEIAAAAVAGALSLADAARIVAVRSRAIARELSGHGGMVAVTAPHDE 4387 Query: 2240 VEQVAGEFPRVSVGAYNGPNT-VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLD 2298 V + + P V V A NGP++ V+SG L+ ++ E++G+R + +A HS +D Sbjct: 4388 VTALLADLPGVCVAAVNGPSSVVVSGDTGGLDTLLAACEEQGVRARRVPVDYASHSAHVD 4447 Query: 2299 PVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVA 2358 + + +P T G T L A YW R+ R V+ ES+R + Sbjct: 4448 RLAESLPAALDGIEPRDGDIPFFSTVTADWHPG-TGLGAAYWHRNLRGTVRLEESLRALV 4506 Query: 2359 ALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHR 2418 G V +E GP PVLT A A+ SLR+ ++ ALA+A+V G Sbjct: 4507 EQGHDVFVECGPHPVLTVGIEDTVAALGADAVALGSLRRDDGGPARVLTALAAAHVEGVP 4566 Query: 2419 PDF--AAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAASGILG--SGKDLASGDT 2474 D+ A H V+LPTY FQRRR+W +D GT G S LA G Sbjct: 4567 VDWRPAVSH---GTAVDLPTYAFQRRRYW-------LDAGTPQGDPAGLDSVVRLADGGA 4616 Query: 2475 IYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPE 2531 + + LS+ +QPWL H +G VVP A+ A G P + + + P+++PE Sbjct: 4617 VLSGSLSLTTQPWLDAHRTHGAAVVPTTALLDWAVRAGDETGLPV-VAALDEHSPLVVPE 4675 Query: 2532 KASREVQLTLHPADGGSVLSFQIHSRPY----GERGADWSLNAEG--------TVDTAGS 2579 + E+QLT+ AD S F +HSR + GE W+ NA G T +G+ Sbjct: 4676 EGHVEIQLTVSAADTDS-RPFSVHSRLHAADAGEPATPWTRNATGDLTDRPTTTPQASGT 4734 Query: 2580 DPDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGD 2639 P A A +DP + L R DL F +++SLW + + + Sbjct: 4735 WPPADA-VAADPAP--VRALAEDRGLDLAAPF------------DTVRSLWRAGTDVLAE 4779 Query: 2640 ILVGAELAEQLGSEPMHPVLM 2660 + + +HP L+ Sbjct: 4780 VALPDAAHADAARFRLHPALL 4800 Score = 607 bits (1566), Expect = e-171 Identities = 382/961 (39%), Positives = 520/961 (54%), Gaps = 26/961 (2%) Query: 1549 RQASTVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYD 1606 +Q S R +P+AVVA++CR+P G P+ WEL GVDAI P +R WD+D + Sbjct: 23 QQLSDAENRDREPVAVVAMACRYPGGVRTPQDLWELARDGVDAISAFPANRGWDLDHLFH 82 Query: 1607 PDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP 1666 PDP G TYTR P FFGISPREA+ ++PQQRL+LET WE LERAG P Sbjct: 83 PDPAHHGTTYTREGGFLHDAGEFDPAFFGISPREALAMDPQQRLLLETSWEALERAGILP 142 Query: 1667 SDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVA 1726 L GS TGVF G +Y S ++ H +TGN + SGR+++ GFEGPAV Sbjct: 143 DTLAGSTTGVFVGTGHGDYDG-ASRGRQKEVAGHLLTGNTVAVASGRLSYTYGFEGPAVT 201 Query: 1727 VDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFD 1786 VDTACSS+LVA+H A ++L+ G+C LALAGG V+ +P SR + L+ GRCK F Sbjct: 202 VDTACSSSLVALHLAVRSLRQGECSLALAGGATVMSTPKMFTEFSRQQGLAADGRCKPFA 261 Query: 1787 ASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLI 1846 A ADG SEG G+++L+RLSDA R+G + AVI S++NQDGAS+GLT PNG +QQRLI Sbjct: 262 AGADGTAWSEGVGLILLERLSDAQRNGHEILAVIRGSAINQDGASNGLTAPNGPSQQRLI 321 Query: 1847 EATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGH 1906 L AGL+ +VD +EAHGTGT LGDPIE Q PLL+GS+K+N GH Sbjct: 322 RQALIDAGLTSGEVDVVEAHGTGTTLGDPIEAQALLNTYGQDRGDAHPLLLGSLKSNTGH 381 Query: 1907 TESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRA 1966 T++ASG AG+IK+V +++HG LP+SLH + P+PH W V ++ E W GR RRA Sbjct: 382 TQAASGVAGVIKMVQAMRHGTLPKSLHVDAPTPHADWATGGVELLTESTTWPETGRPRRA 441 Query: 1967 GVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL---ALSARSPEA 2023 VSSFG +GTNAH+++E+AP DDS + +S +S A Sbjct: 442 AVSSFGVSGTNAHLILEQAPED-----QTPRAEEPGTEPSADDSADTVRSWMVSGKSRAA 496 Query: 2024 LVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXT 2083 + E A R + A+ + DV H R + RA +V Sbjct: 497 VGEQAARLAASVRASDA-SVLDVAHALVSSRVAMDRRAVVVGSDREELLAGLDALAAGEP 555 Query: 2084 PAGVVRGEHVH-RPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPL 2142 VV G A++F GQGSQ+ GMA EL + PVFA V +CA A+ L Sbjct: 556 SVRVVEGTAGEGAGDVAFVFPGQGSQWVGMAVELLGSSPVFAGRVAECAAALEPFTEWSL 615 Query: 2143 LDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVA 2202 LDVL E A L+ QP L+AV + LA +W++ +EP V+GHS G+ AAA VA Sbjct: 616 LDVLNGV--EGAASLERVDVVQPVLWAVMVSLAEVWRAQGVEPGAVIGHSQGEIAAAVVA 673 Query: 2203 GVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVE-QVAGEFPRVSVGAYNGPNT- 2260 G SL+DGAR++A R R +L G MV+V + + V +AG R+SV A NGP++ Sbjct: 674 GGLSLEDGARVVALRSRALRALSGLGGMVSVARNVDEVRGLLAGWEGRISVAAVNGPSSV 733 Query: 2261 VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPL 2320 V+SG E L+E V + G+R +A +A HS ++ + + +P Sbjct: 734 VVSGDAEALDEFVAACDASGVRARRVAVDYASHSAHVERIEEELAGLLAPVAPRSCDVPF 793 Query: 2321 VCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ 2380 +G V+ LDA YW R+ R V+F R + A G V +E+ PV+ + Sbjct: 794 YSTLSGGVI-DTAGLDAGYWYRNLRGTVEFEAGTRALLADGFRVFVEVSAHPVVATGVQE 852 Query: 2381 VWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPR-RPVELPTYPF 2439 + V +LR+ + A +L A+ G D+ + R R V+LPTYPF Sbjct: 853 TIEDASVQAGVVGTLRRDEGGLERFALSLGEAWALGAEVDWETHYAGTRPRHVDLPTYPF 912 Query: 2440 QRRRFW--PKASSIAVDGGTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTV 2497 +R +W P S+ A G A G S + SGD +RLS + D +GT+ Sbjct: 913 RRDWYWLTPAESAAAAATGDPADGDFWSA--VESGD---LTRLSSVLEVTGDDVEAFGTL 967 Query: 2498 V 2498 + Sbjct: 968 L 968 Score = 597 bits (1540), Expect = e-168 Identities = 370/934 (39%), Positives = 505/934 (54%), Gaps = 39/934 (4%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFD 58 +VSA EP A++ A RFPG + EE W L+ +A+S P+DR WD++ +D Sbjct: 1590 VVSAGVTDEP---MAVVAMACRFPGGVTTPEELWHLMAAEVDAVSTPPEDRGWDLDALYD 1646 Query: 59 PDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAP 118 PDP G +R GF+ DV GFD FFG+S RE MDPQ R+L+ET+W E +GI P Sbjct: 1647 PDPERHGTTYSREGGFIQDVAGFDPVFFGISPREALAMDPQQRLLLETSWETFERAGIDP 1706 Query: 119 TSLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAV 178 +L NS TGVFVG T DY ++ ++ G +++ A+GR+SY G +GPAV Sbjct: 1707 GTLRNSATGVFVGSITTDYQVRLGGAAAQEQLAGHLMTGNASSIASGRLSYTYGFEGPAV 1766 Query: 179 AVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTF 238 +DT CSSS+VA+H A Q+LR EC +ALAGG V+ TP + FS LA DGRCK F Sbjct: 1767 TMDTGCSSSMVALHLALQSLRTGECTMALAGGVTVMSTPEPYVEFSRQRGLAADGRCKAF 1826 Query: 239 DAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRV 298 ADG EG G+V+++RL DA R+G + AV+RGSA+NQDGAS GLT PNG +QQRV Sbjct: 1827 AEGADGMGFAEGVGLVLLERLSDARRNGHPVLAVVRGSALNQDGASNGLTAPNGPSQQRV 1886 Query: 299 IADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIG 358 I AL AGL P +V +EAHGTGT LGDPIEAQA G R P PLL+GS K+NIG Sbjct: 1887 IRQALANAGLAPGEVDVVEAHGTGTPLGDPIEAQAILATYGQDRDPARPLLLGSLKSNIG 1946 Query: 359 HLEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRI 418 H + + TLPK L+ P+ + W + +V E+ PW G+PR Sbjct: 1947 HTQAAAGVAGMMKMILAMRQGTLPKSLHITRPTSVVDWSSGAVRLVTESTPWPETGRPRR 2006 Query: 419 AGVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDP-------------RRYSVLPLS-AR 464 AGVSSFG +GTN H+ILEEAPA PA EP DP R + V S A Sbjct: 2007 AGVSSFGISGTNGHLILEEAPA-PEPAEDEPA-DPFTEPSADDSADTVRSWMVSGKSRAA 2064 Query: 465 TPEALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALA 524 E RLA R A + DV+H ++R +++RA +V E + L ALA Sbjct: 2065 VGEQAARLAASVRT-----SDASVLDVAHALVSSRVAMDRRAVVVGRDGEELLAGLDALA 2119 Query: 525 DDRPAPGLVRGESHE-APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADIL 583 P+P LV G + + K A++F GQGSQ+ GMA EL + PVFA V +CA A+ Sbjct: 2120 AGEPSPRLVEGSVGDGSGKVAFVFPGQGSQWVGMAVELLGSSPVFAGRVAECAAALEPFT 2179 Query: 584 EKPLLDVIFDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQ 643 E LLDV+ + ++G + L QP L+AV + LA +W++ G EP V+GHS G+ Sbjct: 2180 EWSLLDVL---NGVEG--AASLERVDVVQPVLWAVMVSLAEVWRAQGVEPGAVIGHSQGE 2234 Query: 644 YSAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPS-LSVAA 702 +AA VAG +EDGAR++A R R +L G M +V + L + +SVAA Sbjct: 2235 IAAAVVAGGLSLEDGARVVALRSRALRALSGLGGMVSVARNVDEVRGLLAGWEGRISVAA 2294 Query: 703 YNG-ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEY 761 NG ++ V+SG A+ L+ VA A GVR + +A HSA ++ I ++ + Sbjct: 2295 VNGPSSVVVSGDAEALDEFVAACDASGVRARRVAVDYASHSAHVERIEEELAGLLAPVAP 2354 Query: 762 REPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPV 821 R +G + + LD YW R+ R VEF R L RV +E+ PV Sbjct: 2355 RSCDVPFYSTLSGGVID-TAGLDAGYWYRNLRGTVEFEAGTRALLADGFRVFVEVSAHPV 2413 Query: 822 LTATALAAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKL 880 + D + V+ +LR + ++ A+A G D+ + R + Sbjct: 2414 VATGVQETIEDASVQAGVVGTLRRDEGGLERFALSLGEAWALGAEVDWETHYAGTRPRHV 2473 Query: 881 DLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTP 914 DLPTY F+ + +W R + +SAG +P Sbjct: 2474 DLPTYAFQRQHYW---PRFAELGGDVSSAGLDSP 2504 Score = 575 bits (1482), Expect = e-161 Identities = 362/931 (38%), Positives = 483/931 (51%), Gaps = 51/931 (5%) Query: 14 FAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRR 71 FAI+G A R PG S E+ W LL DG +A++ P DR WD+ +D P G TR Sbjct: 3706 FAIVGMACRLPGDIHSPEDLWRLLADGADAVAPFPDDRGWDLARLYDSVPEGQGSSRTRE 3765 Query: 72 AGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVG 131 GF+ D FDA FFG+S RE MDPQ R+L+ETAW E +GI P S+ S TGVF G Sbjct: 3766 GGFLHDAADFDADFFGISPREALAMDPQQRLLLETAWETFERAGIDPRSVRGSRTGVFAG 3825 Query: 132 LATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 L++ DYL + EI Y+ G +N+ +GR+SY LGL+GPAV VDTACSSSLVA+ Sbjct: 3826 LSSSDYLKRVTH--VPDEIAGYVNNGNANSIVSGRVSYTLGLEGPAVTVDTACSSSLVAL 3883 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR EC +ALAGG V+ +P ++ FS LA DGRCK F AADG EG Sbjct: 3884 HMALQALRRGECTMALAGGVTVMSSPEIIVDFSRQRGLAADGRCKPFAEAADGTGFSEGV 3943 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 G+++V+RL DA R+G ++ AV+RGSA+NQDGAS GL+ PNG AQQRVI AL AG+ A Sbjct: 3944 GLILVERLSDARRNGHQVLAVVRGSAVNQDGASNGLSAPNGPAQQRVIRQALADAGVGAA 4003 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 +V +EAHGTGT LGDPIEAQA G R PL +GS K+N+GH + Sbjct: 4004 EVDVVEAHGTGTRLGDPIEAQALLATYGRDRDGGHPLFLGSVKSNLGHTQAAAGVAGVMK 4063 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNG--KPRIAGVSSFGFAGT 429 L + LP+ L+ + P+PH+ W + ++ E W G +PR A VSSFG +G Sbjct: 4064 MVLALRHRLLPESLHIDAPTPHVDWADSGVRLLTEATAWPEAGASRPRRAAVSSFGISGH 4123 Query: 430 N-------------AHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEY 476 A +P A T P P LSAR+ AL A Sbjct: 4124 QRPRHPGGGPPPPPARTAASRSPPAPDAAETRPAPLP-----WVLSARSEAALRGQAKAL 4178 Query: 477 RDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRG- 535 L AHP AD++HT T RA LE+RA +V ++ L ALA+ PA +V G Sbjct: 4179 LTHLDAHPGTDPADIAHTLVTRRAQLEKRAVVVGSATGDFRAGLAALAEGSPAAHVVTGG 4238 Query: 536 -ESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDA 594 + +T +F GQGSQ+ GM EL D P FA+ V C EA+A P +D A Sbjct: 4239 RGAGRDRRTVLVFPGQGSQWAGMGAELLDASPAFADRVAACEEALA-----PYVDWSLTA 4293 Query: 595 DELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFD 654 + L QP +AV + LA +W++ G P V+GHS G+ +AA VAG Sbjct: 4294 VLRQEEGAPALDRVDVVQPVTWAVMVALAEVWRAHGLRPAAVLGHSQGEIAAAAVAGALS 4353 Query: 655 VEDGARLIAERGRLFG-SLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSG 712 + D AR++A R R L G M AV + L + P + VAA NG ++ V+SG Sbjct: 4354 LADAARIVAVRSRAIARELSGHGGMVAVTAPHDEVTALLADLPGVCVAAVNGPSSVVVSG 4413 Query: 713 PAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREP-----QRI 767 L++ +A GVR + +A HSA +D + + + +E R+ + Sbjct: 4414 DTGGLDTLLAACEEQGVRARRVPVDYASHSAHVDRLAESLPAALDGIEPRDGDIPFFSTV 4473 Query: 768 LIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATAL 827 D G+ LG AYW R+ R V +S+R L + V +E GP PVLT Sbjct: 4474 TADWHPGTGLG------AAYWHRNLRGTVRLEESLRALVEQGHDVFVECGPHPVLTVGIE 4527 Query: 828 AAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPF 887 L SLR ++ A+AAA+ G D+R +DLPTY F Sbjct: 4528 DTVAALGADAVALGSLRRDDGGPARVLTALAAAHVEGVPVDWRP-AVSHGTAVDLPTYAF 4586 Query: 888 EHRQFWF------SDNRAIDRDTQTASAGSV 912 + R++W D +D + A G+V Sbjct: 4587 QRRRYWLDAGTPQGDPAGLDSVVRLADGGAV 4617 Score = 196 bits (499), Expect = 4e-47 Identities = 130/364 (35%), Positives = 177/364 (48%), Gaps = 12/364 (3%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G H A LA GA +VLTSRR P + E R+ DV Sbjct: 1227 LITGGTGALGAHVARSLAASGARHLVLTSRRGPGSPGAVGLVAELEELGARVTVADCDVA 1286 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D Q+A LL + A LP L G+ H AGVLDD +L A +RF L PK G +H Sbjct: 1287 DRDQLARLLDSLPAGLP-LTGVVHAAGVLDDGVLDALTLDRFEAVLRPKTLGTAHLHELT 1345 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQANYA ANA LD + +RRA+GL T + +GPW GM Sbjct: 1346 RDHDVTLFVLFSSIVGVLGNAGQANYAAANAYLDAVAEQRRAEGLPVTSVAWGPWADAGM 1405 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP--- 3534 A+++ ++ GL P+DP A+ AL +A G ATVL +W+ + +ARP Sbjct: 1406 ATADVLADRMSHDGLAPMDPVTAVAALRAAVAEGVPHATVLDVDWRAYGTAMTAARPSPL 1465 Query: 3535 ----PILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA- 3589 P + L +AA A L +L + ++ +T+ ++ EV LR +SP A Sbjct: 1466 VGDLPEVRRALEAAAATAPDTHALRDRLRGLAPAEQDRLLTDLVRAEVATALRHSSPEAV 1525 Query: 3590 -ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEA 3648 + F DLG DSL A+E+RNR+ + K + T +FDYP + +L L E Sbjct: 1526 DVNRAFKDLGFDSLTAVEVRNRITAATDVK--LPTTLLFDYPNTTAVVAHLRTLLLGDER 1583 Query: 3649 PETA 3652 P A Sbjct: 1584 PVAA 1587 Score = 182 bits (463), Expect = 7e-43 Identities = 183/563 (32%), Positives = 237/563 (42%), Gaps = 66/563 (11%) Query: 1087 LVTRDGQRVTDTDTVVP--EQSCLWGFGRAAALELPHIWGGLADLSGA------DTEWPR 1138 L+ +G T D VP + WG R+A E P + LADL A D+ Sbjct: 4992 LLVTEGAVATGPDDTVPGLADATAWGLLRSAQTEHPGRFL-LADLDPAPGDTDEDSAADA 5050 Query: 1139 LIARITSP-RDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDR--------TYLVTG 1189 LIA + R GE Q A+R V PRLV G P P P T L+TG Sbjct: 5051 LIAAAAAAARTGEHQFAVRAGTVTVPRLVP-AGHPEGAPAPAATAPWGEGTGAGTVLITG 5109 Query: 1190 GLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAH 1248 G G +G VA +L + HG H++LTSRR P + ++ DVAD Sbjct: 5110 GTGTLGALVARHLVTRHGVRHLLLTSRRGPGAPGAAALREELAALGAEAEIVACDVADRE 5169 Query: 1249 DVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDL 1308 +A ++ V AE PL +VH AG + L GL V V K AWHL E D Sbjct: 5170 QLAGVLDAVPAE-HPLTAVVHTAGVLDDGTLDGLTADRVAHVLRPKADAAWHLHELTRD- 5227 Query: 1309 RTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW-----A 1363 T L FV SS A V GG GQ Y AANAFLD LA R G+ A S+ +G W Sbjct: 5228 -TKLTAFVMFSSYAGVAGGPGQANYAAANAFLDALAQHRRASGLPAHSLAWGLWEDRSDL 5286 Query: 1364 AGMADAESRARLEQRGVRTLSPAEALAGM-ADVVAGPVQGVVAKIDWSRFL------PLY 1416 G D ARLE+ G+R L+ + LA + A V ++D +R L PL Sbjct: 5287 TGALDTTGLARLERSGIRPLTAGQGLALLDASTALDTAHLVPVRLD-TRTLRADEVPPLL 5345 Query: 1417 QQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLT-KAPVQQRKSLITNYLRNAV 1475 + R A +S L E+L + QQR L L + Sbjct: 5346 RALARPAVRRAADS---------GPGAATGAPADLRERLAGLSGPQQRALLHRTVLGHLA 5396 Query: 1476 AEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYL 1535 A + A + + GF DLGM SL AVELR R+ G +P TL+ DHP + +L Sbjct: 5397 AVLGHASAASLDADRGFLDLGMSSLTAVELRNRLNADTGLSLPTTLIFDHPDPAALVRHL 5456 Query: 1536 LVEVLGLG----------EQTNVRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLA 1585 E LG G E + A A D A +A + G W+L A Sbjct: 5457 QTE-LGTGAGEPDQAVFAELAALEAAVGGAALDDQDRARLAQRLKALG-------WKLDA 5508 Query: 1586 GGVDAIREVPEDRWDIDEFYDPD 1608 DA + P+D D+D D + Sbjct: 5509 TSQDA--DEPDDDSDLDTTTDDE 5529 Score = 131 bits (329), Expect = 2e-27 Identities = 113/358 (31%), Positives = 156/358 (43%), Gaps = 15/358 (4%) Query: 3298 LITGGLGAIGLHTAAYLA-QLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 LITGG G +G A +L + G ++LTSRR P A+ E A DV Sbjct: 5106 LITGGTGTLGALVARHLVTRHGVRHLLLTSRRGPGAPGAAALREELAALGAEAEIVACDV 5165 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D Q+A +L + AE PL + H AGVLDD L +R L PKA A H Sbjct: 5166 ADREQLAGVLDAVPAE-HPLTAVVHTAGVLDDGTLDGLTADRVAHVLRPKADAAWHLHEL 5224 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 PGQANYA ANA LD L RRA GL A + +G W Sbjct: 5225 TRDTKLTAFVMFSSYAGVAGGPGQANYAAANAFLDALAQHRRASGLPAHSLAWGLWEDRS 5284 Query: 3477 MASSEAAT---ANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQ--RAAKV--- 3528 + T A + G+ PL L L A + ++ + + RA +V Sbjct: 5285 DLTGALDTTGLARLERSGIRPLTAGQGLALLDASTALDTAHLVPVRLDTRTLRADEVPPL 5344 Query: 3529 LGSARPPILDLVLPSAAGEATG-DSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 L + P + S G ATG ++L ++L + PQ+ + + + L AS Sbjct: 5345 LRALARPAVRRAADSGPGAATGAPADLRERLAGLSGPQQRALLHRTVLGHLAAVLGHASA 5404 Query: 3588 PA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 + A FLDLG SL A+ELRNRL++ G ++ T +FD+P L +L +L Sbjct: 5405 ASLDADRGFLDLGMSSLTAVELRNRLNADTG--LSLPTTLIFDHPDPAALVRHLQTEL 5460 >tr|A0ACH1|A0ACH1_STRAM Tax_Id=278992 SubName: Full=Putative polyketide synthase B;[Streptomyces ambofaciens ATCC 23877] Length = 8154 Score = 1835 bits (4753), Expect = 0.0 Identities = 1349/3721 (36%), Positives = 1825/3721 (49%), Gaps = 262/3721 (7%) Query: 15 AIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAG 73 AI+ + R PG A E+ W LL DG +AI D P DR + + T G TRR G Sbjct: 38 AIVAMSCRLPGGVGAPEDLWRLLADGTDAIVDFPDDRGWTQTVAE----TGG--YTRRGG 91 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 FV D FDA FG++ RE MDPQ R+L+E AW E +GI P SLA S+TGVFVG + Sbjct: 92 FVPDAAEFDAALFGINPREALAMDPQQRMLLEAAWEVAERAGIDPHSLAGSDTGVFVGAS 151 Query: 134 T--HDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 +D +G + Y G++ + +GR+SY LGL+GPAV VDTACSSSLVA+ Sbjct: 152 PSGYDTVGRLPESTV-----GYQLTGSAGSVLSGRLSYVLGLEGPAVTVDTACSSSLVAL 206 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR EC AL GG V+ TPA F +A DGRCK+F A ADG EG Sbjct: 207 HLAVQALRQGECGRALVGGVAVITTPAAFTEFGKQGGMASDGRCKSFSAEADGTGWSEGV 266 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 GV++V+RL DA R+G + AVIRGSA+NQDGAS GLT PNG +QQRVI AL A L Sbjct: 267 GVLLVERLSDARRNGHDVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAQLTTV 326 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT+LGDPIE +A + G R + PL +GSAK+N+GH + Sbjct: 327 DVDAVEAHGTGTALGDPIELEALQDTYGRDRTDDRPLWLGSAKSNLGHTQAASGVVGVIK 386 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 L N LP+ L+ P+PH+ WE + ++ + PW R PR GVS+FG +GTNA Sbjct: 387 SVLALRNGLLPRTLHVAVPTPHVVWEGRGVRLLADARPWPRTDVPRRIGVSAFGVSGTNA 446 Query: 432 HVILEEAPAV--GTPATTEPVE---DPRRYSVL-PLSARTPEAL----VRLAGEYRDWLR 481 H+ILEEAPA G + EP + P +L P+SA+T EAL RL+G D Sbjct: 447 HLILEEAPAPLPGDESAGEPADAGAGPLPGPLLWPVSAQTSEALRAQAERLSGRLTDHAE 506 Query: 482 AHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAP 541 HP ADV+ + T RA L +RA ++ L +L PA G+V G E Sbjct: 507 -HP----ADVAWSLATTRAALTRRAVVIGTDEAQLRHGLASLTIGHPAGGVVTGTIDEG- 560 Query: 542 KTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDT 601 +T +LFTGQG+Q GM R L+++ PVFAE ++PL DV+FD G T Sbjct: 561 RTGFLFTGQGAQRAGMGRGLYESFPVFAEAFDAVCAEFDPRRDRPLKDVVFD-----GGT 615 Query: 602 ESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARL 661 E L T + Q LFAVE+ RL +SWG PD+++GHS+G+ +AA AGV + RL Sbjct: 616 E--LDRTAWTQAGLFAVEVAAFRLLESWGVAPDLLLGHSIGEVAAAHCAGVLSLAHACRL 673 Query: 662 IAERGRLFGSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLES 719 + RGRL +LP+GG M AV T E E + + +AA NG + V+SG + L++ Sbjct: 674 VEARGRLMQALPSGGAMLAVEATESEVVEMIAGQ---ADIAAVNGPTSVVVSGSEETLDA 730 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 +G R L SHAFHSAL++P+L +F + +KL++ +P ++ N TG Sbjct: 731 LATRWTGEGRRTRRLTVSHAFHSALMEPMLAEFATVVEKLDFADPVIPVVSNLTGEVAES 790 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 D YW R RQ V FA V L + +E+GP VL A A D P Sbjct: 791 GLLSDPGYWVRQVRQAVRFADGVARLREQGVSRFVELGPDGVLCAMAQQTAADAVCAPL- 849 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 LR D A+A + +G D+R+ P R+++LPTY F+ ++W Sbjct: 850 ---LRRDRDDTATALTALARLWTSGAEVDWRSLL-PAGRRVELPTYAFQRERYW------ 899 Query: 900 IDRDTQTASAGSVTPHRT-QAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQ 958 AG+ P + R E + +L L D + + + N + A + + Sbjct: 900 ---PEALPDAGAAQPSTSPDEDRFWEAVERADLTGLTDTLGLRDDPESLANLVPALSSWR 956 Query: 959 RSTHVDP---DARYEIRWDXXXXXXXXXXXXXDWILV----GDDTAAVLEFADALTAGGH 1011 RS D RY+ RW W+LV GDD V A+AL A G Sbjct: 957 RSLRQDSLLDSWRYQARWKPLTLTPGGSLTGT-WLLVTADAGDDAQHV---ANALRASGA 1012 Query: 1012 RHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRR 1071 R + L +D D A L + L AA+ + VV G + P R L L R Sbjct: 1013 RVVELTLTAAD-DRAVLTERLTAAAPDGVVVV---VGGTSPRPSRPT------DLAALLR 1062 Query: 1072 LFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLS 1130 ++A DAE +P+W +TR D D ++ PEQ+ LWG GR AALE P WGGL DL Sbjct: 1063 TYQALADAEPAAPLWCLTRGAVSTGDGDPLLHPEQAPLWGLGRVAALEHPTTWGGLVDLP 1122 Query: 1131 G-ADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVR----RTGEPSDTPLPVREDRTY 1185 D L+A + EDQ+ALR Y R+VR R P T D T Sbjct: 1123 AHGDDSTGDLLAALLGGGAREDQVALRDGQAYGRRIVRAPLPRVSAPRWTT-----DGTV 1177 Query: 1186 LVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVA 1245 LVTGG G +G EVA +LA G H++L SR V V DVA Sbjct: 1178 LVTGGTGGLGGEVARWLARRGVPHLLLLSRHGADAPGADELRAELHALGTQVTVAGCDVA 1237 Query: 1246 DAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEAL 1305 D +A ++ V AE P L G+VHAAG L D+ EV V KV GA L E L Sbjct: 1238 DRESLAAVLAAVPAEFP-LTGVVHAAGVGTPGRLLDTDETEVAEVLRAKVTGAALLDE-L 1295 Query: 1306 TDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-A 1364 TD LD FV SSIA+ WG GQ AY A NAFLD L R RG++ ++ +GPWA Sbjct: 1296 TD---GLDLFVVFSSIAATWGSGGQGAYAAGNAFLDALVEHRRHRGLSGTAIAWGPWAEV 1352 Query: 1365 GMA-DAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQAGRR 1422 GMA D E A L +RG+ + AL +A V V VA +DW F P + A Sbjct: 1353 GMAADDEVAAFLRRRGLSVMDRTVALRALASAVDHDETTVSVADVDWKLFAPAFVSARPS 1412 Query: 1423 AFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RV 1481 L+EL L + L AP +R L+ + +R A+V Sbjct: 1413 PLLAELPDA---RVPARATTDADTPSTALRDALAAAPETERHRLLLDAVRTHTAQVLGHT 1469 Query: 1482 DADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLG 1541 + + F DLG DSL AVELR + G +P TLV DHP + D+LL + G Sbjct: 1470 NVAVVEPRRAFRDLGFDSLTAVELRNLLTSETGLPLPTTLVFDHPTPTALTDHLLGRLFG 1529 Query: 1542 LGEQTNVRQASTVTARTDDPIAVVAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-W 1599 + A D+PIA+V +SCR+PG A E W+L+A G D + + P DR W Sbjct: 1530 DTSAAAAAPSLDTPAAADEPIAIVGMSCRYPGGANSAEQLWDLVASGRDVVTDFPTDRGW 1589 Query: 1600 DIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGL 1659 P+ Y R FGISPREA+ ++PQQRL+LE WE Sbjct: 1590 ---------PEGGDGDYARRGGFVDGATEFDAALFGISPREALAMDPQQRLLLEASWEAF 1640 Query: 1660 ERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALG 1719 E AG P +RTGV G A++ Y L + E H + G + + ISGRVA++ G Sbjct: 1641 EHAGIDPLSQNHTRTGVLIGAASSGYG--LGTDLFTTAEGHVLAGGSNSVISGRVAYSFG 1698 Query: 1720 FEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPV 1779 EGPAV VDTACSS+LVAVH A QAL++G+CD ALAGGV V+ +P +R L+ Sbjct: 1699 LEGPAVTVDTACSSSLVAVHLAVQALRNGECDRALAGGVTVMAAPSIFAEFNRQGGLAGD 1758 Query: 1780 GRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNG 1839 GRCK F +ADG +EG GVLVL+RLSDAVR G V AV+ S+VNQDGAS+GLT PNG Sbjct: 1759 GRCKAFAGAADGTGWAEGVGVLVLERLSDAVRRGHEVLAVVRGSAVNQDGASNGLTAPNG 1818 Query: 1840 GAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGS 1899 +Q+R+I LA A L +DVD +EAHGTGT LGDPIE Q PL +GS Sbjct: 1819 PSQERVIRQALANARLEASDVDVVEAHGTGTRLGDPIEAQALLATYGQGRDEDRPLWLGS 1878 Query: 1900 VKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT 1959 VK+NIGHT++A+G AG+IK+V +L+ G +P +LH + P+PH+ W VR+ W Sbjct: 1879 VKSNIGHTQAAAGVAGVIKMVQALRSGTVPATLHVDEPTPHVDWTTGAVRLAVASRAWPE 1938 Query: 1960 NGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSAR 2019 GR RRAGVSSFG +GTNAHV++E+A P T + L +SA+ Sbjct: 1939 TGRARRAGVSSFGMSGTNAHVIIEQAEP----------VAAPTPEPSTGSAWVPLTVSAK 1988 Query: 2020 SPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXX 2079 S L A R + +S T G D+ DV + + R+ E+RA ++ Sbjct: 1989 SVVGLAAQADRLRELVSGTSGPDLVDVGWSL-LSRAGLEHRAVVLGADRESAAEGLKSVA 2047 Query: 2080 XXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLP 2139 +GVV G V ++F GQGSQ+ GM REL VF + + +C A+ + Sbjct: 2048 AGVASSGVVAG-GVVPGDVVFVFPGQGSQWVGMGRELAGWSGVFREALAECEAALEPWVE 2106 Query: 2140 RPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAA 2199 L +V+ +R LL+ QP L+AV + LARLW+ + P V+GHS G+ AAA Sbjct: 2107 WSLWEVI---ERGDEGLLERVDVVQPVLWAVMVSLARLWRGCGVVPSAVVGHSQGEIAAA 2163 Query: 2200 CVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF-PRVSVGAYNGP 2258 VAG SL+DGAR++A R R +L GG MV+V VE++ G F R+SV A NGP Sbjct: 2164 VVAGGLSLEDGARVVALRSRAILALAGGGGMVSVAEGRGVVEELVGGFGGRLSVAAVNGP 2223 Query: 2259 -NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPT 2317 +TV+SG LEE++ G+R + +A HS ++ V + Sbjct: 2224 GSTVVSGEPGALEELLGLCGVRGVRARRIPVDYASHSVQVEGVRERILAELAEVAPVSSG 2283 Query: 2318 LPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGA 2377 +PL TGA + +DA YW + R V+F E R + A G SV +E P PVL Sbjct: 2284 VPLYSTVTGAPI-DTASMDAGYWFENLRSTVRFEEVTRGLLADGRSVFVECSPHPVLAVG 2342 Query: 2378 AVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTY 2437 + V SLR+G + ALA A+V G D+++V RR VELP Y Sbjct: 2343 VEETAEAAGVDAVVVGSLRRGEGGEERFLTALAEAWVAGAGVDWSSVVPAGRR-VELPAY 2401 Query: 2438 PFQRRRFWPKASSIAVDGGTAASG-------ILGSGKDLASGDTIYTSRLSVKSQPWLAD 2490 FQR R+WP+ + G +A G ILG+ L SG + T RLS S PWL D Sbjct: 2402 AFQRERYWPRP---VMSGDVSAVGQQGLHHAILGATVALPSGGAVLTGRLSPSSHPWLQD 2458 Query: 2491 HVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGG 2547 H + G V+VPG +A +AL A VG+ L+++ P++L ++A +Q+ + D Sbjct: 2459 HAVRGQVLVPGTAFAELALRAGDQVGS-GFLRELVLQTPLVLSDRAGVALQVGIGAPDDS 2517 Query: 2548 SVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDL 2607 S ++ SRP + A W +A G + + +D + P RP DL Sbjct: 2518 GDRSVEVCSRPSDD--AAWVCHATGLLGESAADAPTESTTWPPP---------GSRPVDL 2566 Query: 2608 ---FETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCT 2664 ++ A+ +GP + G L+++W DG+ V + E + G +HP L+D Sbjct: 2567 AGFYDGLAEAGYGYGPAFQG-LRAVW-RDGDTVFAEVELPEAVDPAGF-GIHPALLDAAL 2623 Query: 2665 -GVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFEL 2723 V + G LP + VTL A R AL + Sbjct: 2624 HAVAVTDADADSDADSGTR---LPFAWHGVTL-------HATEATVLRVALTDTPDGLTV 2673 Query: 2724 EFVDLGGRALGGIREFTVKRAPREALLRGLGGDATR-LLYTLGWHEVPPPPSADDAVGTW 2782 VD G + + ++ EA LR +G R L+ L W +P P +A W Sbjct: 2674 RAVDPTGAPVVTVEALVLRDITPEA-LRQVGEQRLREALFALDWTVLPDPGNAPPDTSAW 2732 Query: 2783 LIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXX 2842 L D G P V L Q A A S T Sbjct: 2733 LRLDPD-------GPTPAHDTPPPPVAVLTLPQP-APDAALSADTVHLTT---------- 2774 Query: 2843 XXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPV-DPVQAALWGFGR 2901 ++L V L L +VT V G+ V D A++WG R Sbjct: 2775 ----------QDVLRTVQNWLADDRYLDTRLVVVTRGAVPAVPGQSVTDLAGASVWGLLR 2824 Query: 2902 TTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLL-PWARSG 2960 + +E P R+V D D EP++A+R G+ A RL+ P A Sbjct: 2825 SAQSEHPG---RIVLLDRDPAGTDGDVWPNWAVADDEPQVAIRDGRARAPRLVRPSAADD 2881 Query: 2961 HLTLPRG-GDFVLAPTERGAIDNLRLTETDVPEPD------EGYVQVRVEAAGLNFRDVL 3013 L LP G + L T+ G +D+L + +P PD G V+V V AAG+NFRDVL Sbjct: 2882 GLPLPSGPAAWRLDVTDEGTLDHLAM----LPAPDADAPLTAGQVRVAVRAAGVNFRDVL 2937 Query: 3014 NVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIP 3073 LG+YP D +G + AG VT+ G GV L +G RV+G G ASR + LAP+P Sbjct: 2938 IALGMYP-DRAQMGAEAAGVVTETGPGVHDLAVGDRVFGFFTGGIASRAVTDRRLLAPVP 2996 Query: 3074 DGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFA 3132 G +AA +P T D A+ +PG+ VL+H+A+GGVG+AA+Q+ + G EVF Sbjct: 2997 TGWTFAQAAAVPVVFATAYYGLVDVARARPGESVLVHSAAGGVGMAAVQLGRHLGLEVFG 3056 Query: 3133 TASTFKRSTLRRLGV--KYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKA 3190 TA K TLR G+ ++ SR F ++ A ++G GVDVVLNSL + FV+A+L+ Sbjct: 3057 TAKPSKWGTLRAAGLDDAHIASSRDLAFEERFRATSDGRGVDVVLNSL-AGEFVDASLRL 3115 Query: 3191 TAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARG 3250 GGRFA++++ D+ Q+A P + Y+ DR+R++L EV D G Sbjct: 3116 LGDGGRFADLSRTDLRDAAQVAADHPGVRYQAF---NPAEAGADRVREILGEVLDLFHTG 3172 Query: 3251 EWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHT 3310 LP + + +A SAFR + QARH+GK D + LITGG G +G Sbjct: 3173 VLELLPVTAWDVRDAVSAFRHISQARHVGK--NVLTVPTPLDPDGTVLITGGTGTLGGLL 3230 Query: 3311 AAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARI 3369 A +L + GA +I+L SRR D + R A D D A +AD+L I Sbjct: 3231 ARHLVTEHGARNILLLSRRGADGPGATELLADLHAMGARATVVACDAADRAALADVLTAI 3290 Query: 3370 RAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXX 3429 + PL G+ H AGVLDD + + PER L PK A + Sbjct: 3291 -PDRHPLTGVIHAAGVLDDGVFESMTPERVEAVLRPKVDAAVNLHDLTLDTDLALFVLYS 3349 Query: 3430 XXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ-----GGMASSEAAT 3484 GQANYA AN+ LD L + RRA+GL A + +G W Q G + T Sbjct: 3350 SASATLGTGGQANYAAANSFLDALASYRRARGLPAQSLGWGLWQQASTMTGHLLDDATPT 3409 Query: 3485 AN------ITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILD 3538 T QGL D ++A H + + + R +V R I Sbjct: 3410 GGRTGATLSTEQGLALFDVASATH---------TPHLLPIPLDLARGGEVPALLRGLIRP 3460 Query: 3539 LVLPSAAGEATGDSE-----LLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSR 3593 +A A G +E L +L+ + R V + ++ L A A +R Sbjct: 3461 AGRRAAGRRAAGRNEETHNVLATRLLGLSAADRRDLVLDLVRGNAATVLGHARADAVGAR 3520 Query: 3594 --FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPET 3651 F DLG DSL A+ELRNRL++ G + AT VFD+PT LAE+L +L AP Sbjct: 3521 QAFRDLGFDSLTAVELRNRLNTATG--LRLPATLVFDHPTPTVLAEHLSTRLGGEPAPTP 3578 Query: 3652 A 3652 A Sbjct: 3579 A 3579 Score = 1438 bits (3722), Expect = 0.0 Identities = 955/2472 (38%), Positives = 1271/2472 (51%), Gaps = 154/2472 (6%) Query: 10 PTPSFAIIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKV 67 P AI+G A R PG AS + W L+ +G +A S P DR W ++ Sbjct: 3588 PGEPIAIVGMACRLPGGVASPADLWPLVSEGMDATSGFPADRGWPLDIV---------GA 3638 Query: 68 VTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTG 127 R GF+D+ T FDA FG+S RE MDPQ R+L+ETAW A E +GIA + S+TG Sbjct: 3639 EAARGGFLDEATDFDAALFGISPREALAMDPQQRLLLETAWEAFESAGIATSDAHGSSTG 3698 Query: 128 VFVGLATHDY-LGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSS 186 VF+G A Y GM + ++ GT+ + A+GR++Y GL+GPAV VDTACSS Sbjct: 3699 VFIGAAHAQYGYGMRLPDNAL----GHLMTGTTTSVASGRLAYTFGLEGPAVTVDTACSS 3754 Query: 187 SLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYV 246 SLVA+H A QALR EC +ALAGG VL TP + F LA DGRCK F AAADG Sbjct: 3755 SLVALHLAVQALRNGECAMALAGGVTVLATPGVITEFDRQRGLASDGRCKAFSAAADGTG 3814 Query: 247 RGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRA 306 EG G+++V+RL DA R G + AV+RGSA+NQDGAS GLT PNG +Q+RVI AL A Sbjct: 3815 MSEGVGLLLVERLSDAERLGHEVLAVVRGSAVNQDGASNGLTAPNGPSQERVIRQALANA 3874 Query: 307 GLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXX 366 L ++V +EAHGTGT LGDPIEAQA G GR + PL +GS K+NIGH + Sbjct: 3875 RLAASEVDAVEAHGTGTRLGDPIEAQALLATYGQGRDEDRPLWLGSVKSNIGHTQAAAGV 3934 Query: 367 XXXXXXXXXLENETLPKH-LNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFG 425 + N LP L+ + P+PH+ W +E++ E PW + +P AGVSSFG Sbjct: 3935 AGVIKMVLAMRNGVLPPTLLHADEPTPHVDWSAGAVELLTEARPWPLSDRPHRAGVSSFG 3994 Query: 426 FAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQ 485 +GTNAHVILE A + AT P L +SA TPE L A L A + Sbjct: 3995 ISGTNAHVILEAAGPAHSHATPTIPSTPGPVGWL-VSAHTPEGLRAQAERLATTLSA-AR 4052 Query: 486 ARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAW 545 A DV+ + T R L+ RAA+V + L ALA PA +V G E +TA+ Sbjct: 4053 AEAHDVAWSLATTRTALDHRAAVVGEGHGELVAGLTALACGEPAANVVSGAVAEG-RTAF 4111 Query: 546 LFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPL 605 LFTGQG+Q GM R L++ PVFAE + LE+P+ + +FD +LD Sbjct: 4112 LFTGQGAQRAGMGRGLYEAYPVFAEAFDTVCAELDRRLERPVREAVFDGVDLD------- 4164 Query: 606 RHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAER 665 T + Q LFAVE+ + RL +SWG PDV++GHS+G+ +AA AGVF + D L+A R Sbjct: 4165 -RTVWTQAGLFAVEVAVFRLLESWGVVPDVLLGHSIGEIAAAHCAGVFSLADACALVAAR 4223 Query: 666 GRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATL 724 GRL +LPAGG M AV AE + D L VAA NG ++ V+SG A ++ A Sbjct: 4224 GRLMQALPAGGAMLAV--RATEAEVVEDVRGRLDVAAVNGPSSVVVSGDAGTIDEFAAKW 4281 Query: 725 VADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLD 784 +G R L SHAFHSAL++P+L DF S A+ + Y P+ L+ +A + Sbjct: 4282 RGEGRRTSRLTVSHAFHSALMEPMLADFASVAESVSYCAPRIPLV-----AATAGAQPAT 4336 Query: 785 GAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLR 844 YW R R+ V FA +V + + +E+GP VL A D P LR Sbjct: 4337 PEYWVRQVRETVRFADAVTEVTERGVTRFVEVGPDGVLCGMAQQTAADAVFAP----VLR 4392 Query: 845 PTTADHRQITEAVAAAYAAG---HLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAID 901 +H A+ +AAG H P P R++ LPTY F+ ++W + D Sbjct: 4393 RDRDEHETALAALGRLWAAGAEIHWPAV----LPAGRRVALPTYAFQRERYWPEPSTVAD 4448 Query: 902 RDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRST 961 A + ++ + ELA I ++ L+ +R Sbjct: 4449 ------PAAPADADEARFWAAVDRADLTELADTIGLPDASAPLDALVPALSRWRRSRRQE 4502 Query: 962 HVDPDARYEIRWDXXXXXXXXXXXXXDWILVG---DDTAAVLEFADALTAGGHRHQIVAL 1018 V RY + W LV D A+AL A G Sbjct: 4503 SVIGSWRYRVTWTPLQHLTSTPATLSGTWLVAAAPADAEPAARLAEALRAAG-------- 4554 Query: 1019 PGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAAND 1078 A++ R A + AG A AP D + L R +D Sbjct: 4555 -------AEVAPLDREADRQGAHASATVAGVVALAPSSDAVTES-------VALLRQLDD 4600 Query: 1079 AELRSPIWLVTRDGQRVTDTDTV-VPEQSCLWGFGRAAALELPHIWGGLADLSGA-DTEW 1136 AEL +P+W++T + +D + Q+ WG GR AALE P WGGL DL D Sbjct: 4601 AELDAPVWMLTSGAVSIGRSDPLREVAQAQAWGLGRVAALEQPRRWGGLIDLPAEFDARA 4660 Query: 1137 PRLIARITSPRDGEDQIALRGDAVYAPRLVR-RTGEPSDTPLPVREDRTYLVTGGLGAIG 1195 RL+ + + GEDQ+A+R Y RLVR GEP+ T P T LVTGG GA+G Sbjct: 4661 ARLLISVLAGGTGEDQVAVRSSGAYGRRLVRAAAGEPTGT--PYTPSGTVLVTGGTGALG 4718 Query: 1196 LEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMT 1255 VA +LA GA +VL RR + C+ V+ DV D +A ++ Sbjct: 4719 KRVARWLAERGAPRLVLLGRRGADAPGTTELAAELAAHGCEATVVACDVTDRTALAAVLD 4778 Query: 1256 TVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFF 1315 + E PL G+VHAAG PL+ D+AE+ RV GKV GA HL E + TDLD F Sbjct: 4779 AIPEE-HPLTGVVHAAGFGQAVPLADTDEAEITRVLDGKVTGAAHLDELTRE--TDLDLF 4835 Query: 1316 VSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW-AAGM-ADAESRA 1373 V SSIA+ WG GQ Y AANA LD L + R G + SV +GPW GM A + Sbjct: 4836 VVFSSIAATWGSGGQGVYAAANAHLDALVEQRRAHGRSGTSVAWGPWEGEGMAAQGGAEE 4895 Query: 1374 RLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQAGRRAFLSELESEL 1432 L + G+ ++P AL + V V VA +DW RF P + A L+EL Sbjct: 4896 YLYRHGLVAMAPDLALRALERAVELDESCVTVADVDWERFAPAFTSGRDSALLTELTDAA 4955 Query: 1433 XXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR-NAVAEVTRVDADEIRDEAG 1491 ++L AP +R ++ + +R A + A+ I + Sbjct: 4956 QALAPATDAAERGSTFR---DELVAAPESRRHGMLLDLIRARAAVSLGHASAEAIDPDRS 5012 Query: 1492 FFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQA 1551 F D G DSL A+ELR + G +P TLV DHP + A++L GL E+T Sbjct: 5013 FRDAGFDSLTAIELRNLLGADTGLTLPATLVFDHPSPTALAEHLSA---GLLERTGTDAG 5069 Query: 1552 STVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDP 1609 T D+PIA+V +S R+P G + E WEL+A G D E P DR W P Sbjct: 5070 PTAVGAVDEPIAIVGMSARYPGGVRNAEQLWELVAHGADGTAEFPADREW---------P 5120 Query: 1610 DTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDL 1669 FGISPREA+ ++PQQRL+LE WE E AG P L Sbjct: 5121 SDVVAGAAARGGFVDGATEFDAGLFGISPREALAMDPQQRLLLEASWEAFESAGLNPRSL 5180 Query: 1670 RGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDT 1729 RG GVF G +++ Y + + ++ + + G A + ISGRVA+ G EGPAV VDT Sbjct: 5181 RGRPVGVFAGASSSGYGG--AGDDLEGAGGYLLAGTANSVISGRVAYTFGLEGPAVTVDT 5238 Query: 1730 ACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASA 1789 ACSS+LVA+H A QAL++G+C+LALAGGV V++SP R L+ GRCK+F A Sbjct: 5239 ACSSSLVALHWAAQALRNGECELALAGGVTVMVSPAAFAEFDRQDGLASDGRCKSFAGGA 5298 Query: 1790 DGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEAT 1849 DG EG GVLVL+RLSDA R+G + AV+ S+VNQDGAS+GLT PNG +QQR+I Sbjct: 5299 DGTGWGEGVGVLVLERLSDARRNGHEILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQA 5358 Query: 1850 LARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTES 1909 LA AGL+ +VD +EAHGTGT LGDPIE Q PL +GSVK+NIGHT++ Sbjct: 5359 LATAGLAPGEVDVVEAHGTGTRLGDPIEAQALLATYGQGRDEDRPLWLGSVKSNIGHTQA 5418 Query: 1910 ASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVS 1969 ASG AG+IK+V++++HGVLP +LH + P+PH+ W V+++ + PW R RRAGVS Sbjct: 5419 ASGVAGVIKMVMAMRHGVLPATLHVDEPTPHVDWSTGAVKLLTDARPWTVTDRPRRAGVS 5478 Query: 1970 SFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLA---------LSARS 2020 SFG +GTNAH+L+E AP +DD V A LSA++ Sbjct: 5479 SFGISGTNAHILLESAP-------------------SSDDEASVPARAPRPLGWTLSAKT 5519 Query: 2021 PEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXX 2080 + L A R L A +D DV + R+ ++RA +V Sbjct: 5520 ADGLRAQAARLRG-LVAERHIDPYDVAWSLATTRAALDHRAVVVGTDRDELLAGLAALAR 5578 Query: 2081 XXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPR 2140 T A + E R TA+LFTGQG+Q GM R L++T PV+A + L Sbjct: 5579 GGTAAHTLSAE-ATRGRTAFLFTGQGAQRAGMGRGLYETFPVYADAFDAVCAELEPHLEH 5637 Query: 2141 PLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAAC 2200 P+ DV+F L T +AQ LFAVE+ + RL +SW + PDV+LGHSVG+ AAA Sbjct: 5638 PVRDVVF-----DGTGLDRTVWAQAGLFAVEVAVFRLLESWGVVPDVLLGHSVGELAAAH 5692 Query: 2201 VAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFA-DAEHVEQVAGEFPRVSVGAYNGPN 2259 AGVFSL D RL+A RGR+ +LP GG M+AV A +AE VE + G R+ V A NGP+ Sbjct: 5693 CAGVFSLPDACRLVAARGRLMQALPVGGAMLAVEATEAEVVEVIEG---RLDVAAVNGPS 5749 Query: 2260 T-VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTL 2318 + V+SG E +EE + D+G R L SHAFHS L++P+L P + Sbjct: 5750 SVVVSGAAETVEEFAALWRDQGRRTRRLTVSHAFHSVLMEPMLTEFAAVLEKTAFAEPRI 5809 Query: 2319 PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAA 2378 P+V + TG YW R R+ V+FA+ V + G + L+E+GP VL G A Sbjct: 5810 PVVSDLTGRPAEPGLLSSPDYWVRQVREAVRFADGVEWLRREGVTRLVELGPDGVLCGMA 5869 Query: 2379 VQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYP 2438 Q + + AP LR D ALA + G D++ RR V LPTYP Sbjct: 5870 RQAGIDAVCAP----VLRADRDDTVTALLALAQLWTDGADADWSTTAPGGRR-VALPTYP 5924 Query: 2439 FQRRRFWPKASS 2450 FQR R+WP+A++ Sbjct: 5925 FQRDRYWPRATA 5936 Score = 1418 bits (3671), Expect = 0.0 Identities = 953/2460 (38%), Positives = 1283/2460 (52%), Gaps = 112/2460 (4%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G +AR+PG +AE+ W L+ G + ++ P DR W PS R Sbjct: 5081 AIVGMSARYPGGVRNAEQLWELVAHGADGTAEFPADREW---------PSDVVAGAAARG 5131 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GFVD T FDA FG+S RE MDPQ R+L+E +W A E +G+ P SL GVF G Sbjct: 5132 GFVDGATEFDAGLFGISPREALAMDPQQRLLLEASWEAFESAGLNPRSLRGRPVGVFAGA 5191 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 ++ Y G A D+L Y+ GT+N+ +GR++Y GL+GPAV VDTACSSSLVA+H Sbjct: 5192 SSSGY-GGAGDDLE--GAGGYLLAGTANSVISGRVAYTFGLEGPAVTVDTACSSSLVALH 5248 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC+LALAGG V+++PA F LA DGRCK+F ADG GEG G Sbjct: 5249 WAAQALRNGECELALAGGVTVMVSPAAFAEFDRQDGLASDGRCKSFAGGADGTGWGEGVG 5308 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V+V++RL DA R+G I AV+RGSA+NQDGAS GLT PNG +QQRVI AL AGL P + Sbjct: 5309 VLVLERLSDARRNGHEILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALATAGLAPGE 5368 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G GR + PL +GS K+NIGH + Sbjct: 5369 VDVVEAHGTGTRLGDPIEAQALLATYGQGRDEDRPLWLGSVKSNIGHTQAASGVAGVIKM 5428 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP L+ + P+PH+ W ++++ + PW +PR AGVSSFG +GTNAH Sbjct: 5429 VMAMRHGVLPATLHVDEPTPHVDWSTGAVKLLTDARPWTVTDRPRRAGVSSFGISGTNAH 5488 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVS 492 ++LE AP+ A+ P PR LSA+T + L A R L A DV+ Sbjct: 5489 ILLESAPSSDDEASV-PARAPRPLG-WTLSAKTADGLRAQAARLRG-LVAERHIDPYDVA 5545 Query: 493 HTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQGS 552 + T RA L+ RA +V R+ + L ALA A + E+ +TA+LFTGQG+ Sbjct: 5546 WSLATTRAALDHRAVVVGTDRDELLAGLAALARGGTAAHTLSAEATRG-RTAFLFTGQGA 5604 Query: 553 QYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYAQ 612 Q GM R L++T PV+A+ + LE P+ DV+FD LD T +AQ Sbjct: 5605 QRAGMGRGLYETFPVYADAFDAVCAELEPHLEHPVRDVVFDGTGLD--------RTVWAQ 5656 Query: 613 PALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGSL 672 LFAVE+ + RL +SWG PDV++GHSVG+ +AA AGVF + D RL+A RGRL +L Sbjct: 5657 AGLFAVEVAVFRLLESWGVVPDVLLGHSVGELAAAHCAGVFSLPDACRLVAARGRLMQAL 5716 Query: 673 PAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLVADGVRC 731 P GG M AV + + L VAA NG ++ V+SG A+ +E A G R Sbjct: 5717 PVGGAMLAVEATEAEVVEVIEG--RLDVAAVNGPSSVVVSGAAETVEEFAALWRDQGRRT 5774 Query: 732 DWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRH 791 L SHAFHS L++P+L +F + +K + EP+ ++ + TG YW R Sbjct: 5775 RRLTVSHAFHSVLMEPMLTEFAAVLEKTAFAEPRIPVVSDLTGRPAEPGLLSSPDYWVRQ 5834 Query: 792 ARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTADHR 851 R+ V FA V L L+E+GP VL A A D P LR D Sbjct: 5835 VREAVRFADGVEWLRREGVTRLVELGPDGVLCGMARQAGIDAVCAPV----LRADRDDTV 5890 Query: 852 QITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASAGS 911 A+A + G D+ P R++ LPTYPF+ ++W A+ R A+ Sbjct: 5891 TALLALAQLWTDGADADWST-TAPGGRRVALPTYPFQRDRYWPRATAAVTRPAAHATDSR 5949 Query: 912 VTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEI 971 +E I+ LA L+D + L L++ Q+R RY Sbjct: 5950 FWD-------AVEHEDIDALADLLDDPRTLDLLGAALPMLSSWRRQRRKESAIDSWRYLA 6002 Query: 972 RWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDT 1031 W W++V ++ T R AL G+ A+ +LV T Sbjct: 6003 TWRPVADLPAHPALTGRWLVVVPESQP--------TPAPAREVSSALVGAGAEAVRLVPT 6054 Query: 1032 L--RAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLR---RLFRAANDAELRSPIW 1086 RAA A L V +G + A D + GLR L +A DA + +P+W Sbjct: 6055 SSDRAALAARLAAVGPVSGVVSLAAWADDETPRPGPSAGLRLTLSLLQALGDAGIDAPLW 6114 Query: 1087 LVTRDGQRVTDTDTVVPEQSC-LWGFGRAAALELPHIWGGLADL-SGADTEWPRLIARIT 1144 +T V +D S +WG GR AALE P WGGL D+ S D +A + Sbjct: 6115 ALTSGAVSVGRSDASPAAVSAQIWGLGRVAALEQPDRWGGLLDIPSVLDARAGARLAAVL 6174 Query: 1145 SPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLAS 1204 GEDQ+A+R VY RLVR S TP LVTGG GA+G VA +LA Sbjct: 6175 GGDTGEDQVAVRAAGVYGRRLVRAESAGS-TPWSPSRPGAVLVTGGTGALGAVVARWLAD 6233 Query: 1205 HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPL 1264 G HVVL RR V V T DV D +A + + AE PL Sbjct: 6234 RGVPHVVLMGRRGTRAPGVTGLVGELADVGTRVTVETGDVTDRVALAGALERLPAE-HPL 6292 Query: 1265 AGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASV 1324 G+VHAAG + L L + V A KV G L E +L+FFV+ SS+A Sbjct: 6293 IGVVHAAGVLDDGTLDALTPERFETVLAAKVSGLVALDEVTGG--AELEFFVAFSSLAGT 6350 Query: 1325 WGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRA---RLEQRGVR 1381 G GQ Y AANAF+D R RG+ VS+ +GPWA A+ +A RL + G+ Sbjct: 6351 VGSAGQGNYAAANAFVDAWMQGRRARGLPGVSIAWGPWAQDGMAADDQAVADRLRRGGLS 6410 Query: 1382 TLSPAEALAGMAD-VVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXX 1440 L P A+A +A +V G V+A IDWS+F G RA S L +EL Sbjct: 6411 PLDPELAVAALAGALVPGDQDPVIADIDWSQFAA--GLTGARA--SALLTELPEAASART 6466 Query: 1441 XXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDS 1499 +LT AP +R +++ +R+ A V A+ + F DLG DS Sbjct: 6467 PATEADPATEFRAELTAAPAARRGAMLLAAVRSWAATVLGHGSAEAVGAGQAFRDLGFDS 6526 Query: 1500 LMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTN---VRQASTVTA 1556 L AVE R G +P +LV D P ++ A YL E+ G GE V A+ Sbjct: 6527 LAAVEFRNLAGVRTGLRLPASLVFDRPTPAELARYLGEELFG-GEPVPAPAVVAATRAVT 6585 Query: 1557 RTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGK 1614 D+P+A+V ++CR PG P+ W+LL GGVDA+ P DR WD+ PD+P Sbjct: 6586 AADEPLALVGMACRLPGGVGSPDELWDLLIGGVDAMTTFPTDRGWDLTAL----PDSP-- 6639 Query: 1615 TYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRT 1674 T FGISPREA+ ++PQQRL+LETVWE E AG P +RG Sbjct: 6640 --TLRGGFVDGVAEFDAGLFGISPREALAMDPQQRLLLETVWETFESAGVDPRAVRGRSV 6697 Query: 1675 GVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSA 1734 G+F G +Y +L+ + + ++ H TGNA +SGRV++A G EGPAV VDTACSS+ Sbjct: 6698 GMFVGTNGQDYPVVLAGSADEGLDAHAATGNAAAVLSGRVSYAFGLEGPAVTVDTACSSS 6757 Query: 1735 LVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVR 1794 LVA+H A QAL+ G+CDLALAGGV+V+ + +R L+ GRCK F A ADG Sbjct: 6758 LVALHLAAQALRRGECDLALAGGVSVMSTEAAFTEFARQGGLADDGRCKAFSADADGTGW 6817 Query: 1795 SEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAG 1854 EG GVL+++RL+DA R+G RV A++ S+VNQDGAS+GLT PNG +QQR+I LA A Sbjct: 6818 GEGVGVLLVERLADARRNGHRVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADAR 6877 Query: 1855 LSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAA 1914 LS ++VD +EAHGTGT LGDPIE Q PL +GS+K+N+GHT++A+G A Sbjct: 6878 LSPSEVDAVEAHGTGTRLGDPIEAQALLATYGQDRDADRPLWLGSIKSNLGHTQAAAGVA 6937 Query: 1915 GLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFT 1974 G+IK+VL+L+HG LP +LH + P+ + W A V ++ PW R RRAGVSSFG + Sbjct: 6938 GVIKMVLALRHGTLPPTLHADEPTEQVDWSAGAVELLTRARPWPEADRPRRAGVSSFGIS 6997 Query: 1975 GTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDW 2034 GTNAHV++E P G +P L +S RS AL A R + Sbjct: 6998 GTNAHVILEAEP-------VPADEAAPTDRPGDGTTPPWL-VSGRSATALAAQAGRLHEV 7049 Query: 2035 LSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVH 2094 LSA P + ADV + + R+ E+RA ++ AG++ E Sbjct: 7050 LSARPEVAPADVARSL-LSRADLEHRAVVMGTGYDDLMAGLAALATGEPAAGLI-SETTG 7107 Query: 2095 RPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETA 2154 TA+LFTGQG+Q GM REL++ P +A + RPL DV+F Sbjct: 7108 EGRTAFLFTGQGAQRAGMGRELYEAFPAYADAFDAVCAELDLKHERPLRDVVF-----DG 7162 Query: 2155 DLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLM 2214 D L T +AQ LFAVE+ + RL +S+ + PDV+LGHS+G+ AAA AGV SL D L+ Sbjct: 7163 DGLDRTVWAQAGLFAVEVAVFRLLESFGVVPDVLLGHSIGEIAAAHCAGVLSLADACELV 7222 Query: 2215 AERGRMFGSLPEGGRMVAVFA-DAEHVEQVAGEFPRVSVGAYNGPNT-VLSGPGEDLEEI 2272 A+RGR+ +LP GG M+AV A +AE ++ V R+ + A NGP++ V+SG E +EE Sbjct: 7223 AQRGRLMQALPAGGAMLAVEATEAEILDAVRS---RLDIAAVNGPSSLVVSGVTEVVEEF 7279 Query: 2273 VERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQ 2332 R+ EG R + L SHAFHS L++P+L P +P++ GA LT Sbjct: 7280 AARWSAEGRRTSRLTVSHAFHSALMEPMLAGFAEVVETMTFAEPRVPVIPAAAGADLT-- 7337 Query: 2333 TPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAV 2392 TP YW R R+ V+F + VR + G + +E+GP VL A AP Sbjct: 7338 TP---DYWVRQVRETVRFGDGVRQLTEQGVTRFVELGPDGVLCAMARGAGVTGAFAP--- 7391 Query: 2393 ASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIA 2452 LR+ + R + +AL + G D+ A R + LPTY FQR R+WP+ ++ A Sbjct: 7392 -VLRRDRDEVRTVWEALGRIWAVGVDVDWTAAVPPHGRRIALPTYAFQRDRYWPEPATAA 7450 Score = 853 bits (2204), Expect = 0.0 Identities = 586/1552 (37%), Positives = 794/1552 (51%), Gaps = 83/1552 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 A++G A R PG S +E W LL G +A++ P DR WD+ P +P T R Sbjct: 6592 ALVGMACRLPGGVGSPDELWDLLIGGVDAMTTFPTDRGWDLTAL----PDSP----TLRG 6643 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GFVD V FDA FG+S RE MDPQ R+L+ET W E +G+ P ++ + G+FVG Sbjct: 6644 GFVDGVAEFDAGLFGISPREALAMDPQQRLLLETVWETFESAGVDPRAVRGRSVGMFVGT 6703 Query: 133 ATHDY---LGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLV 189 DY L ++DE ++A+ A G + A +GR+SY GL+GPAV VDTACSSSLV Sbjct: 6704 NGQDYPVVLAGSADE----GLDAHAATGNAAAVLSGRVSYAFGLEGPAVTVDTACSSSLV 6759 Query: 190 AIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGE 249 A+H A QALR ECDLALAGG +V+ T A F+ LA DGRCK F A ADG GE Sbjct: 6760 ALHLAAQALRRGECDLALAGGVSVMSTEAAFTEFARQGGLADDGRCKAFSADADGTGWGE 6819 Query: 250 GCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLR 309 G GV++V+RL DA R+G R+ A++RGSA+NQDGAS GLT PNG +QQRVI AL A L Sbjct: 6820 GVGVLLVERLADARRNGHRVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLS 6879 Query: 310 PADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXX 369 P++V +EAHGTGT LGDPIEAQA G R + PL +GS K+N+GH + Sbjct: 6880 PSEVDAVEAHGTGTRLGDPIEAQALLATYGQDRDADRPLWLGSIKSNLGHTQAAAGVAGV 6939 Query: 370 XXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGT 429 L + TLP L+ + P+ + W +E++ PW +PR AGVSSFG +GT Sbjct: 6940 IKMVLALRHGTLPPTLHADEPTEQVDWSAGAVELLTRARPWPEADRPRRAGVSSFGISGT 6999 Query: 430 NAHVILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQAR 487 NAHVILE P A P + P + P +S R+ AL AG + L A P+ Sbjct: 7000 NAHVILEAEPVPADEAA--PTDRPGDGTTPPWLVSGRSATALAAQAGRLHEVLSARPEVA 7057 Query: 488 LADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLF 547 ADV+ + +RA LE RA ++ + + L ALA PA GL+ + E +TA+LF Sbjct: 7058 PADVARSL-LSRADLEHRAVVMGTGYDDLMAGLAALATGEPAAGLISETTGEG-RTAFLF 7115 Query: 548 TGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRH 607 TGQG+Q GM REL++ P +A+ + E+PL DV+FD D LD Sbjct: 7116 TGQGAQRAGMGRELYEAFPAYADAFDAVCAELDLKHERPLRDVVFDGDGLD--------R 7167 Query: 608 TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGR 667 T +AQ LFAVE+ + RL +S+G PDV++GHS+G+ +AA AGV + D L+A+RGR Sbjct: 7168 TVWAQAGLFAVEVAVFRLLESFGVVPDVLLGHSIGEIAAAHCAGVLSLADACELVAQRGR 7227 Query: 668 LFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANT-VLSGPAKDLESAVATLVA 726 L +LPAGG M AV AE L L +AA NG ++ V+SG + +E A A Sbjct: 7228 LMQALPAGGAMLAVEAT--EAEILDAVRSRLDIAAVNGPSSLVVSGVTEVVEEFAARWSA 7285 Query: 727 DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGA 786 +G R L SHAFHSAL++P+L F + + + EP+ +I G+ L T D Sbjct: 7286 EGRRTSRLTVSHAFHSALMEPMLAGFAEVVETMTFAEPRVPVIPAAAGADL---TTPD-- 7340 Query: 787 YWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPT 846 YW R R+ V F VR L + +E+GP VL A A A A P LR Sbjct: 7341 YWVRQVRETVRFGDGVRQLTEQGVTRFVELGPDGVLCAMARGAGVTGAFAPV----LRRD 7396 Query: 847 TADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQT 906 + R + EA+ +A G D+ A P R++ LPTY F+ ++W Sbjct: 7397 RDEVRTVWEALGRIWAVGVDVDWTAAVPPHGRRIALPTYAFQRDRYW-------PEPATA 7449 Query: 907 ASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPD 966 A A + P ++ +E + E+A+ + + VL L++ Q R Sbjct: 7450 APAPAQAPVESRFWAAVEREDVTEVASTLRLAARPDALAEVLPALSSWRRQSRQYAAVDG 7509 Query: 967 ARYEIRWDXXXXXXXXXXXXXDWILV---GDDTAAVLEFADALTAGGHRHQIVALPGSDA 1023 RY + W W+LV GD+ + +AL G + + + Sbjct: 7510 WRYRVEWTPVAVPDAPLDGT--WLLVTEAGDEYGVGV--GEALRGSGAHVVPLPVDATHP 7565 Query: 1024 DEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRS 1083 D +L L A VVH A + L L +A DA + Sbjct: 7566 DRHELAARLGALVGDFRGVVHPAG--------------RRADLAVALTLVQALGDAGWTA 7611 Query: 1084 PIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIAR 1142 P+W +TR V D V E + +WGFG+A ALE PH WGGL DLS + +A Sbjct: 7612 PLWTLTRGAVAVDAADRVTRAEHARVWGFGQAVALEHPHRWGGLVDLSSDGDQDLTRLAA 7671 Query: 1143 ITSPRDGEDQIALRGDAVYAPRLVR--RTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG 1200 + GEDQ+ALR A RLVR R ++ P R T LVTGG GA+G VA Sbjct: 7672 VLRGDTGEDQLALREGRFLARRLVRADRPDWVAEAWTPSRPG-TVLVTGGTGALGASVAR 7730 Query: 1201 YLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAE 1260 +LA G H++LT RR + V + DV D +A L++ V A+ Sbjct: 7731 WLAERGVSHLLLTGRRGARAPGADELLAELRALGAEATVASCDVTDREALAELLSAVPAD 7790 Query: 1261 LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS 1320 P L G+VHAAG + P+ A++ + GKV GA HL + D DL+ FV SS Sbjct: 7791 RP-LLGVVHAAGVAQSGPVETTRLADIAEITDGKVLGAAHLDQLTRD--ADLELFVLFSS 7847 Query: 1321 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-AGMA-DAESRARLEQR 1378 IA+ WG GQ Y A NA+LD LA R +R + A+SV +GPWA AGMA E+ L +R Sbjct: 7848 IAATWGSGGQALYAAGNAYLDALAQRRADRKLAALSVAWGPWAGAGMAVSQEAEQFLRRR 7907 Query: 1379 GVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXX 1437 G+ L PA A+A +A V G VA +DW+RF P + L EL E Sbjct: 7908 GLTPLDPALAVAALAQAVEDGETNVTVADVDWTRFTPAFTSGRPSPLLREL-PEATGAVA 7966 Query: 1438 XXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEA-GFFDLG 1496 L +L +R + +T +R A+ V R DA E D A F DLG Sbjct: 7967 STGTPTEEEADTGLRARLATLSTAERLAELTELIRGALVVVLRYDAHEQIDGARPFRDLG 8026 Query: 1497 MDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNV 1548 DSL AVE R + + G +P T+V D+P + D+L + G T++ Sbjct: 8027 FDSLTAVEFRDVLARECGTPLPSTIVFDYPTPAALVDHLHATLPGADPVTDI 8078 Score = 725 bits (1871), Expect = 0.0 Identities = 496/1297 (38%), Positives = 674/1297 (51%), Gaps = 77/1297 (5%) Query: 1176 PLPVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYA 1234 P P+ D T L+TGG G +G +A +L + HGA +++L SRR Sbjct: 3208 PTPLDPDGTVLITGGTGTLGGLLARHLVTEHGARNILLLSRRGADGPGATELLADLHAMG 3267 Query: 1235 CDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGK 1294 V+ D AD +A ++T + + PL G++HAAG + + V+ V K Sbjct: 3268 ARATVVACDAADRAALADVLTAIP-DRHPLTGVIHAAGVLDDGVFESMTPERVEAVLRPK 3326 Query: 1295 VWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTA 1354 V A +L + D TDL FV SS ++ G GQ Y AAN+FLD LA R RG+ A Sbjct: 3327 VDAAVNLHDLTLD--TDLALFVLYSSASATLGTGGQANYAAANSFLDALASYRRARGLPA 3384 Query: 1355 VSVNFGPW--AAGMAD--AESRARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKI--D 1408 S+ +G W A+ M + R TLS + LA + DV + + I D Sbjct: 3385 QSLGWGLWQQASTMTGHLLDDATPTGGRTGATLSTEQGLA-LFDVASATHTPHLLPIPLD 3443 Query: 1409 WSR-------FLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQ 1461 +R L + AGRRA L +L Sbjct: 3444 LARGGEVPALLRGLIRPAGRRA------------AGRRAAGRNEETHNVLATRLLGLSAA 3491 Query: 1462 QRKSLITNYLR-NAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVT 1520 R+ L+ + +R NA + AD + F DLG DSL AVELR R+ G +P T Sbjct: 3492 DRRDLVLDLVRGNAATVLGHARADAVGARQAFRDLGFDSLTAVELRNRLNTATGLRLPAT 3551 Query: 1521 LVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPES 1579 LV DHP + A++L + G T +T A +PIA+V ++CR PG P Sbjct: 3552 LVFDHPTPTVLAEHLSTRLGGEPAPTPAAPPTTAAA-PGEPIAIVGMACRLPGGVASPAD 3610 Query: 1580 FWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISP 1638 W L++ G+DA P DR W +D G R FGISP Sbjct: 3611 LWPLVSEGMDATSGFPADRGWPLD--------IVGAEAARGGFLDEATDFDAA-LFGISP 3661 Query: 1639 REAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIE 1698 REA+ ++PQQRL+LET WE E AG A SD GS TGVF G A +Y + + D Sbjct: 3662 REALAMDPQQRLLLETAWEAFESAGIATSDAHGSSTGVFIGAAHAQYGYGMRLP--DNAL 3719 Query: 1699 PHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGV 1758 H +TG + SGR+A+ G EGPAV VDTACSS+LVA+H A QAL++G+C +ALAGGV Sbjct: 3720 GHLMTGTTTSVASGRLAYTFGLEGPAVTVDTACSSSLVALHLAVQALRNGECAMALAGGV 3779 Query: 1759 NVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCA 1818 VL +P + R R L+ GRCK F A+ADG SEG G+L+++RLSDA R G V A Sbjct: 3780 TVLATPGVITEFDRQRGLASDGRCKAFSAAADGTGMSEGVGLLLVERLSDAERLGHEVLA 3839 Query: 1819 VIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEV 1878 V+ S+VNQDGAS+GLT PNG +Q+R+I LA A L+ ++VD +EAHGTGT LGDPIE Sbjct: 3840 VVRGSAVNQDGASNGLTAPNGPSQERVIRQALANARLAASEVDAVEAHGTGTRLGDPIEA 3899 Query: 1879 QXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQS-LHFENP 1937 Q PL +GSVK+NIGHT++A+G AG+IK+VL++++GVLP + LH + P Sbjct: 3900 QALLATYGQGRDEDRPLWLGSVKSNIGHTQAAAGVAGVIKMVLAMRNGVLPPTLLHADEP 3959 Query: 1938 SPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXX 1997 +PH+ W A V ++ E PW + R RAGVSSFG +GTNAHV++E A P Sbjct: 3960 TPHVDWSAGAVELLTEARPWPLSDRPHRAGVSSFGISGTNAHVILEAAGP---------A 4010 Query: 1998 XXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHF 2057 + P +SA +PE L A R LSA + DV + R+ Sbjct: 4011 HSHATPTIPSTPGPVGWLVSAHTPEGLRAQAERLATTLSAARA-EAHDVAWSLATTRTAL 4069 Query: 2058 EYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELF 2117 ++RAA+V + A VV G V TA+LFTGQG+Q GM R L+ Sbjct: 4070 DHRAAVVGEGHGELVAGLTALACGEPAANVVSGA-VAEGRTAFLFTGQGAQRAGMGRGLY 4128 Query: 2118 DTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARL 2177 + PVFA+ + L RP+ + +F + D L T + Q LFAVE+ + RL Sbjct: 4129 EAYPVFAEAFDTVCAELDRRLERPVREAVF----DGVD-LDRTVWTQAGLFAVEVAVFRL 4183 Query: 2178 WQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFA-D 2236 +SW + PDV+LGHS+G+ AAA AGVFSL D L+A RGR+ +LP GG M+AV A + Sbjct: 4184 LESWGVVPDVLLGHSIGEIAAAHCAGVFSLADACALVAARGRLMQALPAGGAMLAVRATE 4243 Query: 2237 AEHVEQVAGEFPRVSVGAYNGPNT-VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSE 2295 AE VE V G R+ V A NGP++ V+SG ++E ++ EG R + L SHAFHS Sbjct: 4244 AEVVEDVRG---RLDVAAVNGPSSVVVSGDAGTIDEFAAKWRGEGRRTSRLTVSHAFHSA 4300 Query: 2296 LLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVR 2355 L++P+L P +PLV A G P +YW R R+ V+FA++V Sbjct: 4301 LMEPMLADFASVAESVSYCAPRIPLV-----AATAGAQPATPEYWVRQVRETVRFADAVT 4355 Query: 2356 TVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVG 2415 V G + +E+GP VL G A Q + + AP LR+ + AL + Sbjct: 4356 EVTERGVTRFVEVGPDGVLCGMAQQTAADAVFAP----VLRRDRDEHETALAALGRLWAA 4411 Query: 2416 GHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIA 2452 G + AV RR V LPTY FQR R+WP+ S++A Sbjct: 4412 GAEIHWPAVLPAGRR-VALPTYAFQRERYWPEPSTVA 4447 Score = 597 bits (1539), Expect = e-167 Identities = 370/903 (40%), Positives = 500/903 (55%), Gaps = 27/903 (2%) Query: 1549 RQASTVTARTDDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDRWDIDEFYDP 1607 RQ + +PIA+VA+SCR PG PE W LLA G DAI + P+DR + Sbjct: 24 RQNREMRQAAREPIAIVAMSCRLPGGVGAPEDLWRLLADGTDAIVDFPDDR----GWTQT 79 Query: 1608 DPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPS 1667 +T G YTR FGI+PREA+ ++PQQR++LE WE ERAG P Sbjct: 80 VAETGG--YTRRGGFVPDAAEFDAALFGINPREALAMDPQQRMLLEAAWEVAERAGIDPH 137 Query: 1668 DLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAV 1727 L GS TGVF G + + Y + + + +TG+A + +SGR+++ LG EGPAV V Sbjct: 138 SLAGSDTGVFVGASPSGYDTV--GRLPESTVGYQLTGSAGSVLSGRLSYVLGLEGPAVTV 195 Query: 1728 DTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDA 1787 DTACSS+LVA+H A QAL+ G+C AL GGV V+ +P + ++ GRCK+F A Sbjct: 196 DTACSSSLVALHLAVQALRQGECGRALVGGVAVITTPAAFTEFGKQGGMASDGRCKSFSA 255 Query: 1788 SADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIE 1847 ADG SEG GVL+++RLSDA R+G V AVI S+VNQDGAS+GLT PNG +QQR+I Sbjct: 256 EADGTGWSEGVGVLLVERLSDARRNGHDVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIR 315 Query: 1848 ATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHT 1907 LA A L+ DVD +EAHGTGT LGDPIE++ PL +GS K+N+GHT Sbjct: 316 QALANAQLTTVDVDAVEAHGTGTALGDPIELEALQDTYGRDRTDDRPLWLGSAKSNLGHT 375 Query: 1908 ESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAG 1967 ++ASG G+IK VL+L++G+LP++LH P+PH+ W+ VR++ + PW RR G Sbjct: 376 QAASGVVGVIKSVLALRNGLLPRTLHVAVPTPHVVWEGRGVRLLADARPWPRTDVPRRIG 435 Query: 1968 VSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVEL 2027 VS+FG +GTNAH+++EEAP L G P + +SA++ EAL Sbjct: 436 VSAFGVSGTNAHLILEEAPAPL--PGDESAGEPADAGAGPLPGPLLWPVSAQTSEALRAQ 493 Query: 2028 ARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGV 2087 A R L+ ADV + R+ RA ++ GV Sbjct: 494 AERLSGRLT-DHAEHPADVAWSLATTRAALTRRAVVIGTDEAQLRHGLASLTIGHPAGGV 552 Query: 2088 VRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLF 2147 V G + T +LFTGQG+Q GM R L+++ PVFA+ RPL DV+F Sbjct: 553 VTGT-IDEGRTGFLFTGQGAQRAGMGRGLYESFPVFAEAFDAVCAEFDPRRDRPLKDVVF 611 Query: 2148 ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSL 2207 E L T++ Q LFAVE+ RL +SW + PD++LGHS+G+ AAA AGV SL Sbjct: 612 DGGTE----LDRTAWTQAGLFAVEVAAFRLLESWGVAPDLLLGHSIGEVAAAHCAGVLSL 667 Query: 2208 DDGARLMAERGRMFGSLPEGGRMVAVFA-DAEHVEQVAGEFPRVSVGAYNGP-NTVLSGP 2265 RL+ RGR+ +LP GG M+AV A ++E VE +AG+ + A NGP + V+SG Sbjct: 668 AHACRLVEARGRLMQALPSGGAMLAVEATESEVVEMIAGQ---ADIAAVNGPTSVVVSGS 724 Query: 2266 GEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRT 2325 E L+ + R+ EG R L SHAFHS L++P+L P +P+V N T Sbjct: 725 EETLDALATRWTGEGRRTRRLTVSHAFHSALMEPMLAEFATVVEKLDFADPVIPVVSNLT 784 Query: 2326 GAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEH 2385 G V D YW R RQ V+FA+ V + G S +E+GP VL A Q + Sbjct: 785 GEVAESGLLSDPGYWVRQVRQAVRFADGVARLREQGVSRFVELGPDGVLCAMAQQTAADA 844 Query: 2386 MAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFW 2445 + AP LR+ D ALA + G D+ ++ RR VELPTY FQR R+W Sbjct: 845 VCAP----LLRRDRDDTATALTALARLWTSGAEVDWRSLLPAGRR-VELPTYAFQRERYW 899 Query: 2446 PKA 2448 P+A Sbjct: 900 PEA 902 Score = 554 bits (1428), Expect = e-155 Identities = 358/899 (39%), Positives = 481/899 (53%), Gaps = 36/899 (4%) Query: 3 SAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPD 60 S + P AI+G + R+PG A SAE+ W L+ GR+ ++D P DR W Sbjct: 1539 SLDTPAAADEPIAIVGMSCRYPGGANSAEQLWDLVASGRDVVTDFPTDRGW--------- 1589 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P RR GFVD T FDA FG+S RE MDPQ R+L+E +W A EH+GI P S Sbjct: 1590 PEGGDGDYARRGGFVDGATEFDAALFGISPREALAMDPQQRLLLEASWEAFEHAGIDPLS 1649 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 ++ TGV +G A+ Y G+ +D T E ++ G SN+ +GR++Y GL+GPAV V Sbjct: 1650 QNHTRTGVLIGAASSGY-GLGTDLFT--TAEGHVLAGGSNSVISGRVAYSFGLEGPAVTV 1706 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVA+H A QALR ECD ALAGG V+ P+ F+ LA DGRCK F Sbjct: 1707 DTACSSSLVAVHLAVQALRNGECDRALAGGVTVMAAPSIFAEFNRQGGLAGDGRCKAFAG 1766 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADG EG GV+V++RL DAVR G + AV+RGSA+NQDGAS GLT PNG +Q+RVI Sbjct: 1767 AADGTGWAEGVGVLVLERLSDAVRRGHEVLAVVRGSAVNQDGASNGLTAPNGPSQERVIR 1826 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 AL A L +DV +EAHGTGT LGDPIEAQA G GR + PL +GS K+NIGH Sbjct: 1827 QALANARLEASDVDVVEAHGTGTRLGDPIEAQALLATYGQGRDEDRPLWLGSVKSNIGHT 1886 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 + L + T+P L+ + P+PH+ W + + + W G+ R AG Sbjct: 1887 QAAAGVAGVIKMVQALRSGTVPATLHVDEPTPHVDWTTGAVRLAVASRAWPETGRARRAG 1946 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL 480 VSSFG +GTNAHVI+E+A V P T EP + L +SA++ L A R+ + Sbjct: 1947 VSSFGMSGTNAHVIIEQAEPVAAP-TPEP-STGSAWVPLTVSAKSVVGLAAQADRLRELV 2004 Query: 481 RAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEA 540 L DV + +RA LE RA ++ RESA E L ++A + G+V G Sbjct: 2005 SGTSGPDLVDVGWSL-LSRAGLEHRAVVLGADRESAAEGLKSVAAGVASSGVVAG-GVVP 2062 Query: 541 PKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD 600 ++F GQGSQ+ GM REL VF E + +C A+ +E L +VI D Sbjct: 2063 GDVVFVFPGQGSQWVGMGRELAGWSGVFREALAECEAALEPWVEWSLWEVIERGD----- 2117 Query: 601 TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGAR 660 E L QP L+AV + LARLW+ G P VVGHS G+ +AA VAG +EDGAR Sbjct: 2118 -EGLLERVDVVQPVLWAVMVSLARLWRGCGVVPSAVVGHSQGEIAAAVVAGGLSLEDGAR 2176 Query: 661 LIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPS-LSVAAYNG-ANTVLSGPAKDLE 718 ++A R R +L GG M +V E L + LSVAA NG +TV+SG LE Sbjct: 2177 VVALRSRAILALAGGGGMVSVAEGRGVVEELVGGFGGRLSVAAVNGPGSTVVSGEPGALE 2236 Query: 719 SAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALG 778 + GVR + +A HS ++ + + + ++ L TG+ + Sbjct: 2237 ELLGLCGVRGVRARRIPVDYASHSVQVEGVRERILAELAEVAPVSSGVPLYSTVTGAPID 2296 Query: 779 RSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTA----TALAAWPDPA 834 ++ +D YW + R V F + R L V +E P PVL TA AA D Sbjct: 2297 TAS-MDAGYWFENLRSTVRFEEVTRGLLADGRSVFVECSPHPVLAVGVEETAEAAGVDAV 2355 Query: 835 TTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFW 893 V+ SLR + A+A A+ AG D+ + P R+++LP Y F+ ++W Sbjct: 2356 ----VVGSLRRGEGGEERFLTALAEAWVAGAGVDWSSV-VPAGRRVELPAYAFQRERYW 2409 Score = 162 bits (411), Expect = 7e-37 Identities = 123/355 (34%), Positives = 156/355 (43%), Gaps = 12/355 (3%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G A +LA G +VL RR + R+ DV Sbjct: 6215 LVTGGTGALGAVVARWLADRGVPHVVLMGRRGTRAPGVTGLVGELADVGTRVTVETGDVT 6274 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A L R+ AE PL G+ H AGVLDD L A PERF T LA K G Sbjct: 6275 DRVALAGALERLPAE-HPLIGVVHAAGVLDDGTLDALTPERFETVLAAKVSGLVALDEVT 6333 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQ NYA ANA +D + RRA+GL I +GPW Q GM Sbjct: 6334 GGAELEFFVAFSSLAGTVGSAGQGNYAAANAFVDAWMQGRRARGLPGVSIAWGPWAQDGM 6393 Query: 3478 ASSEAATAN-ITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPI 3536 A+ + A A+ + GL PLDP A+ ALA + G + +W + A L AR Sbjct: 6394 AADDQAVADRLRRGGLSPLDPELAVAALAGALVPGDQDPVIADIDWSQFAAGLTGARASA 6453 Query: 3537 LDLVLPSAAG------EATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA- 3589 L LP AA EA +E +L P +R + ++ L S A Sbjct: 6454 LLTELPEAASARTPATEADPATEFRAELTAAPAARRGAMLLAAVRSWAATVLGHGSAEAV 6513 Query: 3590 -ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A F DLG DSL A+E RN + G + A+ VFD PT LA YL +L Sbjct: 6514 GAGQAFRDLGFDSLAAVEFRNLAGVRTG--LRLPASLVFDRPTPAELARYLGEEL 6566 Score = 150 bits (378), Expect = 5e-33 Identities = 114/363 (31%), Positives = 161/363 (44%), Gaps = 18/363 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAA--D 3355 L+TGG GA+G A +LA+ G ++LT RR A A + + E A D Sbjct: 7716 LVTGGTGALGASVARWLAERGVSHLLLTGRRGA--RAPGADELLAELRALGAEATVASCD 7773 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 V D +A+LL+ + A+ P L G+ H AGV + K GA+H Sbjct: 7774 VTDREALAELLSAVPADRP-LLGVVHAAGVAQSGPVETTRLADIAEITDGKVLGAAHLDQ 7832 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQA YA NA LD L +R + L A + +GPW Sbjct: 7833 LTRDADLELFVLFSSIAATWGSGGQALYAAGNAYLDALAQRRADRKLAALSVAWGPWAGA 7892 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP 3535 GMA S+ A + +GL PLDP+ A+ ALA+ + +G TV +W R S RP Sbjct: 7893 GMAVSQEAEQFLRRRGLTPLDPALAVAALAQAVEDGETNVTVADVDWTRFTPAFTSGRPS 7952 Query: 3536 ILDLVLPSAAG---------EATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 L LP A G E D+ L +L + +R +TE ++ + LR + Sbjct: 7953 PLLRELPEATGAVASTGTPTEEEADTGLRARLATLSTAERLAELTELIRGALVVVLRYDA 8012 Query: 3587 PPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLP 3644 + F DLG DSL A+E R+ L + G + +T VFDYPT L ++L LP Sbjct: 8013 HEQIDGARPFRDLGFDSLTAVEFRDVLARECG--TPLPSTIVFDYPTPAALVDHLHATLP 8070 Query: 3645 DAE 3647 A+ Sbjct: 8071 GAD 8073 Score = 148 bits (373), Expect = 2e-32 Identities = 115/351 (32%), Positives = 149/351 (42%), Gaps = 12/351 (3%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G A +LA+ GA +VL RR D + H C A DV Sbjct: 4709 LVTGGTGALGKRVARWLAERGAPRLVLLGRRGADAPGTTELAAELAAHGCEATVVACDVT 4768 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A +L I E PL G+ H AG L+ + L K GA+H Sbjct: 4769 DRTALAAVLDAIPEE-HPLTGVVHAAGFGQAVPLADTDEAEITRVLDGKVTGAAHLDELT 4827 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQ YA ANA LD LV +RRA G T + +GPW GM Sbjct: 4828 RETDLDLFVVFSSIAATWGSGGQGVYAAANAHLDALVEQRRAHGRSGTSVAWGPWEGEGM 4887 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 A+ A + GL+ + P AL AL + TV +W+R A S R L Sbjct: 4888 AAQGGAEEYLYRHGLVAMAPDLALRALERAVELDESCVTVADVDWERFAPAFTSGRDSAL 4947 Query: 3538 DLVLPSAA-------GEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA- 3589 L AA A S +L+ P +R G + + ++ L AS A Sbjct: 4948 LTELTDAAQALAPATDAAERGSTFRDELVAAPESRRHGMLLDLIRARAAVSLGHASAEAI 5007 Query: 3590 -ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 F D G DSL AIELRN L + G T+ AT VFD+P+ LAE+L Sbjct: 5008 DPDRSFRDAGFDSLTAIELRNLLGADTG--LTLPATLVFDHPSPTALAEHL 5056 >tr|A4D934|A4D934_9NOSO Tax_Id=76335 (crpB)SubName: Full=CrpB;[Nostoc sp. ATCC 53789] Length = 3469 Score = 1768 bits (4578), Expect = 0.0 Identities = 1078/2851 (37%), Positives = 1566/2851 (54%), Gaps = 126/2851 (4%) Query: 11 TPSFAIIGYAARFPGAASAEE-YWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVT 69 T AIIG RFPG AS + +W +L++G +AI+ VP +RW+++ ++DP+P +PGK+ T Sbjct: 44 TEPIAIIGMGCRFPGGASTPKGFWEVLKNGVDAITQVPPNRWNLDNYYDPNPESPGKIYT 103 Query: 70 RRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVF 129 GF++ + FDA FG+S RE +DPQ R+L+E W A+E++ I PT L S T VF Sbjct: 104 PYGGFIELLDQFDANLFGISPREAIHLDPQQRLLLEVTWEAIENALINPTELNGSQTSVF 163 Query: 130 VGLATHDYLG--MASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSS 187 G+ +DY +A D +I+AY+ G +++ A+GRISY LGL GP++AVDTACSSS Sbjct: 164 TGICGNDYYQRVIAQDS---EQIDAYVVSGNAHSTASGRISYILGLLGPSLAVDTACSSS 220 Query: 188 LVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVR 247 LV++H AC +LR E +LALAGG N +++P I FS A ML+ +GRCKTFDA+ADG+VR Sbjct: 221 LVSVHLACSSLRRGESNLALAGGVNRIISPEVSIAFSKARMLSFNGRCKTFDASADGFVR 280 Query: 248 GEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAG 307 GEGCGVVV+KRL DA+ D D I AVIRGSAINQDG + GLTVPNG +QQ VI AL+ G Sbjct: 281 GEGCGVVVLKRLSDALTDKDNILAVIRGSAINQDGHTSGLTVPNGPSQQAVIRQALENGG 340 Query: 308 LRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXX 367 + PA++ Y EAHGTGTSLGDPIE A G V G + E+PL++GS KTNIGHLE Sbjct: 341 VEPANISYFEAHGTGTSLGDPIEVGALGTVFGTSHSKEQPLIVGSVKTNIGHLEAAAGVA 400 Query: 368 XXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFA 427 L+N+ + L+F P+P+I W LP+++ + PW NGK RIAGVSSFGF+ Sbjct: 401 GLIKIVLQLQNQQIVPSLHFNQPNPYINWSELPVKIPTQISPWPTNGKSRIAGVSSFGFS 460 Query: 428 GTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQAR 487 GTNAHVILEEAP + + + +L LSA+ +AL + Y ++L A Sbjct: 461 GTNAHVILEEAPTQQSQVKDSDL-GKHPWHILTLSAKCEKALQEMIQSYEEFLSNDNTAT 519 Query: 488 LADVSHTAGTARAHLEQRAALVVNSRESAIELLGAL-ADDRPAPGLVRG--ESHEAPKTA 544 +AD+ +A +R+H + R AL+ S E + L + G+VRG +S + K Sbjct: 520 IADICFSAHISRSHFDYRLALIAPSTEKLRQKLKVFQKNPEDTLGVVRGQVDSKKLAKIV 579 Query: 545 WLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESP 604 +LFTGQGSQY M R+L++T+PVF +T+ +C + + L+K +LD+I+ D ++ S Sbjct: 580 FLFTGQGSQYINMGRQLYETQPVFRQTLEQCEQILQPYLKKSILDIIYPEDNQKLNS-SI 638 Query: 605 LRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAE 664 + T Y Q ALFA+E L +LW+SWG +PDVV+GHSVG+Y AA VAG+F +EDG +LIA Sbjct: 639 IDQTAYTQVALFAIEYALYKLWESWGIKPDVVMGHSVGEYVAATVAGIFSLEDGLKLIAH 698 Query: 665 RGRLFGSLPAGGRMAAVFTAPERAERLTDEY-PSLSVAAYNGANT-VLSGPAKDLESAVA 722 RGRL L +GG M +V + E+ +L Y +++A+ NG + V+SG A+ + + Sbjct: 699 RGRLMQQLSSGGEMLSVMASIEKVNQLIAPYSQKVAIASINGPQSIVISGEAEAIGAVQN 758 Query: 723 TLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTR 782 +L A+ ++ L SHAFHS L++P+L DFE+ A ++ Y +P L+ N TG A ++ Sbjct: 759 SLEAEDIKTKRLQVSHAFHSHLMEPMLADFEAVASEITYNQPNIPLVSNVTG-ARAENSI 817 Query: 783 LDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLAS 842 +YW H RQPV+FA+S+ TL + LEIGP+P L P+ L S Sbjct: 818 ATASYWVNHVRQPVKFAQSMDTLQQEGYSIFLEIGPKPTLLGMGRQCLPEDVGV--WLPS 875 Query: 843 LRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDAR-KLDLPTYPFEHRQFWFSDNRAID 901 LRP D +Q+ +++A Y G D+ F + +R K+ LPTYPF+ +++W + + Sbjct: 876 LRPGQEDWQQMLQSLAELYVHGVKVDWLGFDKDYSRSKVVLPTYPFQRQRYWI---ESTE 932 Query: 902 RDTQTASAGSVTPHRTQAVRLLEDGQIEELAALID--GETVDEQT---LRVLNKLAARHN 956 +Q A+ S T LL G I++LA I+ G+ EQ L L +H Sbjct: 933 SQSQKAAYSSCETKSTPIFDLLIHGNIQQLAQQIEKIGKFSPEQVNLLPEFLEVLVKQHQ 992 Query: 957 QQRSTHVDPDARYEIRWDXXXXXXXXXXXXXD-WILVGDDTAAVLEFADALTAGGHRHQI 1015 +Q D Y+++W W++ D TA + L + H + Sbjct: 993 KQLIIETTKDFLYQVQWKPLVDTQPKTSIKPSHWLIFADTTAVGEKLVQQLQS--HHCEC 1050 Query: 1016 VALPGSDA----DEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLR- 1070 + SD DE L A E + A G+ + P+ ++ + + G + Sbjct: 1051 SLVYRSDCYRKLDEGTY--QLNPTEAQEFEQLIQAIGENSKLPLLHVINLWSLDIQGTQD 1108 Query: 1071 ------------------RLFRAANDAELRSPIWLVTRDGQRV-TDTDTVVPEQSCLWGF 1111 +L + + + +WLVTR Q V + T++V S LWG Sbjct: 1109 LTTTTLKQAQLWGCGTVLQLVKVLTKTKSVAKLWLVTRGAQLVKSQTESVCVAASPLWGM 1168 Query: 1112 GRAAALELPHIWGGLADLS--GADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRT 1169 GR +LE P +WGG+ DL ++E L+ + + ED +ALR D +Y RLV+++ Sbjct: 1169 GRVISLEHPQLWGGMVDLDPISPESEAYTLLQLLVNSNQLEDHLALRADNLYFARLVKQS 1228 Query: 1170 GEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXX 1229 +P D+ + ++++ TYL+TGGLGA+GL A ++ GA H+VLT R++P Sbjct: 1229 LKPYDS-VSLKDNATYLITGGLGALGLHTARWMVQQGARHLVLTGRKQP-NLEAQQIIEE 1286 Query: 1230 XEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDR 1289 ++ + V+ D++D D + + + A LP L G+++AAG + L + + + Sbjct: 1287 LQKLGAQILVLCGDISDEVDATTIFSEIEASLPTLKGVINAAGVLDDALLHSMSWEQFTQ 1346 Query: 1290 VFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRE 1349 V A KV GAWHL LT + LDFFV SS+AS+ G GQ Y AANAF+D LA R Sbjct: 1347 VMAPKVQGAWHLHN-LTQNKA-LDFFVCFSSMASLVGSPGQGNYAAANAFMDALAHHRRG 1404 Query: 1350 RGVTAVSVNFGPWA-AGMA---DAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-V 1404 G+ +S+N+GPWA AGMA D +R R+ G+ L+P + L + ++ + V V Sbjct: 1405 MGLPGLSINWGPWAQAGMAASLDNRNRDRMVASGITPLTPEQGLQVLGQLLEQSLPQVGV 1464 Query: 1405 AKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRK 1464 + WS F + + L EL L L+++L P ++R Sbjct: 1465 LSVQWSVFQEKFSFGNQIPLLLEL---LGETESQQKAFRTKTKQNELLKRLESLPCKERY 1521 Query: 1465 SLITNYLRNAVAEVTRVDADEIRD-EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVM 1523 ++ +++ VA+V ++ ++ E GFFDLGMDSLMAVELR RI Q + +P TL Sbjct: 1522 YVLRTEIQSEVAKVLALNDSQLPGFEQGFFDLGMDSLMAVELRNRITQLLKVTLPSTLSF 1581 Query: 1524 DHPRLSDAADYLLVEVLGLGEQTNVRQ-ASTVTARTDDPIAVVAVSCRFP-GAPDPESFW 1581 D P + Y+ ++L L + +Q V A +PIA++ + C P GA PE FW Sbjct: 1582 DFPNIEQLTKYISSQILDLSTSNDGQQPEQKVKAAEHEPIAIIGMGCSLPGGANTPEKFW 1641 Query: 1582 ELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREA 1641 ELL G A E+P RWD++ +YDPD + GK TR PEFFGISPREA Sbjct: 1642 ELLHSGTSAREEIPAQRWDVNSYYDPDREAAGKMVTRYGHFISGVDQFDPEFFGISPREA 1701 Query: 1642 VWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHL----LSAESIDKI 1697 ++PQ RL+LE W+ LERAG L GVF G ++Y L L E Sbjct: 1702 TAMDPQHRLLLEVSWQALERAGQKVERLSSEPVGVFVGNDGHDYEQLMQKHLEQEPNSTF 1761 Query: 1698 EPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGG 1757 + TGN+ ++ SGR+A+ GF GP V +DTACSS+LVA+HQAC +++ G+C +A+AGG Sbjct: 1762 GTYTCTGNSPSSASGRLAYTFGFTGPTVTIDTACSSSLVAIHQACNSIRLGECQMAIAGG 1821 Query: 1758 VNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVC 1817 V + L+P + + SRA M+SP G CKTFD SADGY R EGCG++VLK LS A DGD + Sbjct: 1822 VKLHLTPSSYIFTSRAGMISPDGLCKTFDISADGYGRGEGCGMVVLKSLSQAQADGDPIL 1881 Query: 1818 AVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIE 1877 A+I S+VNQDG SSGLTVPNG +QQ+LI L +A + AD+ YLEAHGTGT LGDPIE Sbjct: 1882 ALILGSAVNQDGPSSGLTVPNGQSQQKLILQALKQARVEPADISYLEAHGTGTSLGDPIE 1941 Query: 1878 VQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENP 1937 V PL +G+VKTNIGH ESA+G +GLIKVVLSLQH +P +LH + P Sbjct: 1942 VNAAAAVLGLQRSPSQPLWIGTVKTNIGHLESAAGVSGLIKVVLSLQHQQIPANLHLQEP 2001 Query: 1938 SPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXX 1997 +P I W ++V PW + R AGVSSFGFTGTNAHV++ E P + Sbjct: 2002 NPKIDWQPW-LQVPQALTPW-VGSKGRLAGVSSFGFTGTNAHVVLSETPAAIASSTVEY- 2058 Query: 1998 XXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHF 2057 + +L LSA++ AL +LA+RY D L D+ D+C TA R Sbjct: 2059 ----------ERPLHLLQLSAKNDLALAQLAQRYSDHLKTHLEQDLRDICFTANSSRLAH 2108 Query: 2058 EYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTT--AWLFTGQGSQYPGMARE 2115 ++R A+V + +V G+ T A LFTGQGSQY GM R+ Sbjct: 2109 KHRLAVVASNRKELQQKLGNFGTDSERMDLVTGQVSSSQLTKVAMLFTGQGSQYVGMGRQ 2168 Query: 2116 LFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLA 2175 L+ TQP F Q V QCA+ + + L +PLL++L + ++L T++ Q ALFA+E L Sbjct: 2169 LYQTQPTFKQFVDQCAQILENYLDKPLLEILDVAQVQ-ENVLAQTAYTQVALFAIEYALY 2227 Query: 2176 RLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFA 2235 +LW+SW I+PDVV+GHS G+Y AA VAG+FSL+DG +L+A RGR+ LP GG M++V A Sbjct: 2228 KLWESWGIKPDVVMGHSAGEYVAATVAGIFSLEDGLKLIAHRGRLMQQLPSGGEMLSVMA 2287 Query: 2236 DAEHVEQVAGEF-PRVSVGAYNGPNT-VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFH 2293 E V Q+ + +V++ + NGP + V+SG E + + E E I+ L SHAFH Sbjct: 2288 SIEKVNQLIAPYSQKVAIASINGPQSIVISGEAEAIGAVQNSLEAEDIKTKRLQVSHAFH 2347 Query: 2294 SELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAES 2353 S L++P+L P +PLV N TGA + A YW H RQPV+FA+S Sbjct: 2348 SHLMEPMLADFEAVASEITYNQPNIPLVSNVTGA-RAENSIATASYWVNHVRQPVKFAQS 2406 Query: 2354 VRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAY 2413 + T+ G S+ +EIGP+P L G Q PE + + SL+ G D +Q+ +LA Y Sbjct: 2407 MDTLQQEGYSIFLEIGPKPTLLGMGRQCLPEDVGV--WLPSLKPGQEDWQQMLQSLAELY 2464 Query: 2414 VGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWPKASSIAVDGGTAASG------ILGSG 2466 V G + D+ + R V LPTYPFQR+R+W + ++ + S +LG Sbjct: 2465 VHGVKVDWLGFDKDYSRSKVVLPTYPFQRQRYWIETNNNLIHQKQFLSNHKNLHPLLGQR 2524 Query: 2467 KDLAS--GDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA-----VGTPARLK 2519 LA+ + ++S +L H ++ V P A Y +ALAA L+ Sbjct: 2525 LHLAALEQQIRFECQISASQPTYLQHHCVFSQPVFPAAAYLEIALAAGSILFNSDDLILE 2584 Query: 2520 DVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGAD--WSLNAEGTVDTA 2577 D+ + +IL + +Q+ L+ S FQI S ++ W L+ EG + Sbjct: 2585 DIAIQKVLILSKDEINTIQIVLNLQLVQS-YKFQIFSLDINTNSSEPKWILHIEGKILVG 2643 Query: 2578 GSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAV 2637 DP DE +++ P + ++ F + L +G ++ ++K LW +G+A+ Sbjct: 2644 NKDPQLETTNLKAIKDEYNQQI---LPTEFYQKFEEWGLNYGSSFQ-AVKQLWHSEGKAL 2699 Query: 2638 GDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAE 2697 G+I + +HP+L+D V E +LPL ++ + Sbjct: 2700 GEIQLPETEVNVATLYQLHPILLDASFQVLAAVMGKTDNQE-----TYLPLEIKRLQIYR 2754 Query: 2698 KMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDA 2757 + + + + +T ++ +D G + + T+ R REALLR + Sbjct: 2755 SGSNSLWTQVEIGATETNKQTLSGKVCLLDEQGIVVARVEGLTLLRTSREALLRNIEPKF 2814 Query: 2758 TRLLYTLGW--HEVPPPPSADDAV--GTWLI 2784 LY + W + P + D G+WL+ Sbjct: 2815 NNWLYQIHWQTQSISPHNQSIDLTKSGSWLL 2845 Score = 211 bits (537), Expect = 2e-51 Identities = 133/361 (36%), Positives = 183/361 (50%), Gaps = 14/361 (3%) Query: 3296 SYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAAD 3355 +YLITGGLGA+GLHTA ++ Q GA +VLT R+ P+ AQ+ I+E+ ++ +I D Sbjct: 1242 TYLITGGLGALGLHTARWMVQQGARHLVLTGRKQPNLEAQQIIEEL-QKLGAQILVLCGD 1300 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 + DE + + I A LP L G+ + AGVLDDALL + + E+F +APK GA H Sbjct: 1301 ISDEVDATTIFSEIEASLPTLKGVINAAGVLDDALLHSMSWEQFTQVMAPKVQGAWHLHN 1360 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 PGQ NYA ANA +D L RR GL IN+GPW Q Sbjct: 1361 LTQNKALDFFVCFSSMASLVGSPGQGNYAAANAFMDALAHHRRGMGLPGLSINWGPWAQA 1420 Query: 3476 GMASS--EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQ--RAAKVLGS 3531 GMA+S + A G+ PL P L L +++ Q VL W + G+ Sbjct: 1421 GMAASLDNRNRDRMVASGITPLTPEQGLQVLGQLLEQSLPQVGVLSVQWSVFQEKFSFGN 1480 Query: 3532 ARPPILDLV-----LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL-- 3584 P +L+L+ A T +ELLK+L +P +R + +Q EV L L Sbjct: 1481 QIPLLLELLGETESQQKAFRTKTKQNELLKRLESLPCKERYYVLRTEIQSEVAKVLALND 1540 Query: 3585 ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLP 3644 + P F DLG DSLMA+ELRNR+ K T+ +T FD+P I L +Y+ Q+ Sbjct: 1541 SQLPGFEQGFFDLGMDSLMAVELRNRITQLL--KVTLPSTLSFDFPNIEQLTKYISSQIL 1598 Query: 3645 D 3645 D Sbjct: 1599 D 1599 Score = 196 bits (498), Expect = 6e-47 Identities = 156/527 (29%), Positives = 254/527 (48%), Gaps = 43/527 (8%) Query: 1042 VVHIAAGDGAAA---PMRDLLRVQHRTLGGLRRLFRAA--NDAELRSPIWLVTRDGQRVT 1096 ++H+ + D A ++L + Q G + L +A N +P+WLVT+ Q V Sbjct: 2911 IIHLWSLDSTIALRTGAQELQKSQELGCGSVLHLVQALVKNQDMESAPLWLVTQGSQSVG 2970 Query: 1097 DTDTVVP-EQSCLWGFGRAAALELPHIWGGLADLSGA--DTEW-PRLIARITSPRDGEDQ 1152 + + +Q+ LWG GR A E + DL D++ L+ + SP D E+Q Sbjct: 2971 NESLPIQFQQTPLWGLGRVIAQEHRELQCRCLDLDPTMEDSQTVAALLEELLSPGD-ENQ 3029 Query: 1153 IALRGDAVYAPRLVRR--------------TGEPSDTPLP--------VREDRTYLVTGG 1190 IA + RL R+ + +P L ++ + +YL+TGG Sbjct: 3030 IAYCQGVRHVARLERQQKMSTSTQSGLQISSQQPFQLKLSEYKSLDNLIQAEASYLITGG 3089 Query: 1191 LGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDV 1250 LGA+GL+ A ++ G ++VLT RR+P ++ V V+ D++ +V Sbjct: 3090 LGALGLKTAEWMVQQGVKYLVLTGRRQPSAKAQQTIEQL-QKAGAQVLVLCGDISQQENV 3148 Query: 1251 ARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRT 1310 AR++ ++ LP L GI+HAAG + L ++ + +V A KV GAWHL +L Sbjct: 3149 ARIIESIKVSLPALRGIIHAAGILDDGLLLNMNWEKFTQVMAPKVQGAWHLHNLTQNL-- 3206 Query: 1311 DLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-AGMA-- 1367 LDFFV SS+AS+ G GQ Y AANAF+DGLA R G+ +S+N+GPWA GMA Sbjct: 3207 PLDFFVCFSSMASILGSPGQGNYAAANAFMDGLAHHRRGMGLPGLSINWGPWAQEGMAAN 3266 Query: 1368 -DAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQAGRRAFL 1425 D+ + R+ +G+ LS + L + ++ + V V I WS F + + L Sbjct: 3267 LDSPHQDRMVSKGMTFLSSEQGLQVLGQLLEQSIPQVGVLPIQWSVFQEQFSFGNQIPLL 3326 Query: 1426 SELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADE 1485 S+L E +EQL A ++R+ L+ Y+++ +++V + + Sbjct: 3327 SQLVKE---SKSQQKALKTKTKHNEFLEQLKAALPREREKLLIIYIKDEISQVLSLSTSQ 3383 Query: 1486 IRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAA 1532 I + +G+DSLMAVEL R++ + DI + ++ + D A Sbjct: 3384 IDMQQPLNTMGLDSLMAVELHNRLQTDLLVDISIVKFIEDISIVDLA 3430 Score = 170 bits (430), Expect = 4e-39 Identities = 111/330 (33%), Positives = 161/330 (48%), Gaps = 11/330 (3%) Query: 3294 DRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYA 3353 + SYLITGGLGA+GL TA ++ Q G +VLT RR P AQ+ I+++ ++ ++ Sbjct: 3081 EASYLITGGLGALGLKTAEWMVQQGVKYLVLTGRRQPSAKAQQTIEQL-QKAGAQVLVLC 3139 Query: 3354 ADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHX 3413 D+ + VA ++ I+ LP L GI H AG+LDD LL N E+F +APK GA H Sbjct: 3140 GDISQQENVARIIESIKVSLPALRGIIHAAGILDDGLLLNMNWEKFTQVMAPKVQGAWHL 3199 Query: 3414 XXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWG 3473 PGQ NYA ANA +DGL RR GL IN+GPW Sbjct: 3200 HNLTQNLPLDFFVCFSSMASILGSPGQGNYAAANAFMDGLAHHRRGMGLPGLSINWGPWA 3259 Query: 3474 QGGMASS--EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQ--RAAKVL 3529 Q GMA++ + ++G+ L L L +++ Q VL W + Sbjct: 3260 QEGMAANLDSPHQDRMVSKGMTFLSSEQGLQVLGQLLEQSIPQVGVLPIQWSVFQEQFSF 3319 Query: 3530 GSARPPILDLVLPS-----AAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 G+ P + LV S A T +E L+QL +R + +++ E+ L L Sbjct: 3320 GNQIPLLSQLVKESKSQQKALKTKTKHNEFLEQLKAALPREREKLLIIYIKDEISQVLSL 3379 Query: 3585 ASPPAASSRFLD-LGTDSLMAIELRNRLHS 3613 ++ + L+ +G DSLMA+EL NRL + Sbjct: 3380 STSQIDMQQPLNTMGLDSLMAVELHNRLQT 3409 Score = 40.0 bits (92), Expect = 7.0 Identities = 38/121 (31%), Positives = 52/121 (42%), Gaps = 12/121 (9%) Query: 2873 LWIVTE--HGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGS---SEAVDXX 2927 LW+VT+ V ES P+ Q LWG GR E L CR +D D + S+ V Sbjct: 2959 LWLVTQGSQSVGNES-LPIQFQQTPLWGLGRVIAQEHRELQCRCLDLDPTMEDSQTVAAL 3017 Query: 2928 XXXXXXPGIQEPEIAVRQGKLLASRL-----LPWARSGHLTLPRGGDFVLAPTERGAIDN 2982 PG E +IA QG +RL + + L + F L +E ++DN Sbjct: 3018 LEELLSPG-DENQIAYCQGVRHVARLERQQKMSTSTQSGLQISSQQPFQLKLSEYKSLDN 3076 Query: 2983 L 2983 L Sbjct: 3077 L 3077 >tr|Q9KIV3|Q9KIV3_STRAT Tax_Id=1890 (oleAII)SubName: Full=8,8a-deoxyoleandolide synthase 2;[Streptomyces antibioticus] Length = 3816 Score = 1759 bits (4557), Expect = 0.0 Identities = 1303/3801 (34%), Positives = 1826/3801 (48%), Gaps = 278/3801 (7%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI A FPG S E+ W LL G E +S+ P DR WD++E + PDP G R Sbjct: 34 AITSMACHFPGGIESPEQLWELLSAGGEVLSEFPDDRGWDLDEIYHPDPEHSGTSYVRHG 93 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+D T FD FFG+S RE MDPQ R+L+ET+W+ E +G+ P +L S TGVFVG Sbjct: 94 GFLDHATQFDTDFFGISPREALAMDPQQRLLLETSWQLFERAGVDPHTLKGSRTGVFVGA 153 Query: 133 ATHDYLGMASDELTYP-EIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 A ++G A T P E E Y+ G ++A +GRISY GL+GPAV VDTACSSSLVA+ Sbjct: 154 A---HMGYADRVDTPPAEAEGYLLTGNASAVVSGRISYTFGLEGPAVTVDTACSSSLVAL 210 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR EC LA+ GG V+ P + FS LA DGR K F A+ADG+ EG Sbjct: 211 HLAVQALRRGECSLAVVGGVAVMSDPKVFVEFSRQRGLARDGRSKAFAASADGFGFAEGV 270 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 +++++RL DA R G R+ AV+RGSA+NQDGAS GL PNG +QQRVI AL AGL PA Sbjct: 271 SLLLLERLSDARRLGHRVLAVVRGSAVNQDGASNGLAAPNGPSQQRVIRAALADAGLAPA 330 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT LGDPIEAQA G GR P+ +GS K+NIGH + Sbjct: 331 DVDVVEAHGTGTRLGDPIEAQALLATYGQGRTSGRPVWLGSVKSNIGHTQAAAGVAGVMK 390 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKP-RIAGVSSFGFAGTN 430 LE +PK L+ + PSPH+ W +E++ E PW+ + R AG+S+FG +GTN Sbjct: 391 MVLALERGVVPKTLHVDEPSPHVDWSTGAVELLTEERPWEPEAERLRRAGISAFGVSGTN 450 Query: 431 AHVILEEAPAVGTPATTEPVEDPRRYS----VLP--LSARTPEALVRLAGEYRDWLRAHP 484 AHVI+EEAPA P EP R + V+P +S R AL A L AH Sbjct: 451 AHVIVEEAPAEPEP---EPEPGTRVVAAGDLVVPWVVSGRDAGALRAQAAR----LAAHV 503 Query: 485 Q---ARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESH-EA 540 A + DV + R+ E RA +V +S L A PG+V G + E Sbjct: 504 SSTGAGVVDVGWSLVATRSVFEHRAVMVGTDLDSMAGSLAGFAAGGVVPGVVSGVAPAEG 563 Query: 541 PKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD 600 + ++F GQGSQ+ GMA L D PVFAE V +CA + + L++V+ Sbjct: 564 RRVVFVFPGQGSQWVGMAAGLLDACPVFAEAVAECAAVLDPLTGWSLVEVLRGG------ 617 Query: 601 TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGAR 660 E+ L QPAL+AV + LAR W+ +G EP VVGHS G+ +AACVAG + DGAR Sbjct: 618 -EAVLGRVDVVQPALWAVMVSLARTWRYYGVEPAAVVGHSQGEIAAACVAGGLSLADGAR 676 Query: 661 LIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPS-LSVAAYNG-ANTVLSGPAKDLE 718 ++ R R + GG M +V R + D Y LSVAA NG ++TV+SG A+ L+ Sbjct: 677 VVVLRSRAIARIAGGGGMVSVSLPAGRVRTMLDTYGGRLSVAAVNGPSSTVVSGDAQALD 736 Query: 719 SAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALG 778 +A +GVR + +A HSA +D + D+ + + T L Sbjct: 737 ELLAGCEREGVRARRVPVDYASHSAQMDQLRDELLEALADITPQHSSVPFFSTVTADWLD 796 Query: 779 RSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQ 838 +T LD YW + R+ V F ++V L +E P PVL Sbjct: 797 -TTALDAGYWFTNLRETVRFQEAVEGLVAQGMGAFVECSPHPVLVPGIEQTLDTVEADAV 855 Query: 839 VLASLRPTTADHRQITEAVAAAYAAGHLPDF-RAFRQPDARKLDLPTYPFEHRQFWFSDN 897 L SLR + ++A A+ G D+ R F R +DLPTYPF+ ++FW + Sbjct: 856 ALGSLRRDEGGLGRFLTSLAEAFVQGVPVDWSRTFEGASPRTVDLPTYPFQRQRFWLEGS 915 Query: 898 RAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRV-LNKLAARHN 956 A+ + A V + + E+ A + + +D + L + L L++ Sbjct: 916 PALSSNGVEGEAD---------VAFWDAVEREDSAVVAEELGIDAKALHMTLPALSSWRR 966 Query: 957 QQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILV-----GDDTAAVLEFADALTAGGH 1011 ++R RY + W W+LV D A+ GG Sbjct: 967 RERQRRKVQRWRYRVEWKRLPNSRAQESLQGGWLLVVPQGRAGDVRVTQSVAEVAAKGGE 1026 Query: 1012 RHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRR 1071 ++ + D A + L V +A + A A L +L + Sbjct: 1027 A-TVLEVDALHPDRAAYAEALTRWPGVRGVVSFLAWEEQALAEHPVLSAGLAASLALAQA 1085 Query: 1072 LFRAANDAELRSPIWLVTRDGQRVTDTDT---VVPEQSCLWGFGRAAALELPHIWGGLAD 1128 L E +WLVT + DT + P + LWGFGR ALE P +WGGL D Sbjct: 1086 LIDVGGSGESAPRLWLVTEAAVVIGAADTGAVIDPVHAQLWGFGRVLALEHPELWGGLID 1145 Query: 1129 LSG-------------ADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDT 1175 L AD L + + GEDQ+A+R Y PRLVR G Sbjct: 1146 LPAVAGEPGSITDHAHADLLATVLATMVQAAARGEDQVAVRTTGTYVPRLVRSGGSAHSG 1205 Query: 1176 PLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYAC 1235 + T LVTGG+G + + +LA +GA VVL + + + Sbjct: 1206 ARRWQPRDTVLVTGGMGPLTAHIVRWLADNGADQVVLLGG-QGADGEAEALRAEFDGHTT 1264 Query: 1236 DVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKV 1295 + + D D+ + L+ E PL ++HA + ++ D R + K+ Sbjct: 1265 KIELADVDTEDSDALRSLLDRTTGE-HPLRAVIHAPTVVEFASVAESDLVRFARTISSKI 1323 Query: 1296 WGAWHLSEALTDLRT--DLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVT 1353 G L E L+ + T D+ FF SS+A VWG GQ+AY A NAFLD +A R RG+ Sbjct: 1324 AGVEQLDEVLSGIDTAHDVVFF---SSVAGVWGSAGQSAYAAGNAFLDAVAQHRRLRGLP 1380 Query: 1354 AVSVNFGPWAAGMADAE-SRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDWSR 1411 SV + PW + A + L++RG+R LS ALA + +V+ V VVA +DW R Sbjct: 1381 GTSVAWTPWDDDRSLASLGDSYLDRRGLRALSIPGALASLQEVLDQDEVHAVVADVDWER 1440 Query: 1412 FLPLYQQAGRRAFLSELESE----LXXXXXXXXXXXXXXXXXXLVEQLTK-APVQQRKSL 1466 F + R +F ++ L LV +L +Q++ L Sbjct: 1441 FYAGFSAVRRTSFFDDVHDAHRPALSTAATNDGQARDEDGGTELVRRLRPLTETEQQREL 1500 Query: 1467 ITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHP 1526 ++ A + D ++ + F ++G DSL AV+LR R+ G +P TLV D+P Sbjct: 1501 VSLVQSEVAAVLGHSSTDAVQPQRAFREIGFDSLTAVQLRNRLTATTGMRLPTTLVFDYP 1560 Query: 1527 RLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAPD-PESFWELLA 1585 + A+YL E+ G+ DDP+ +V ++CRFPG D PE+FW+LL Sbjct: 1561 TTNGLAEYLRSELFGVSGAPADLSVVRNADEEDDPVVIVGMACRFPGGIDTPEAFWKLLE 1620 Query: 1586 GGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWI 1644 G D I E+P +R WD++ +PDP+ G + TR FFGISPREA+ + Sbjct: 1621 AGGDVISELPANRGWDMERLLNPDPEAKGTSATRYGGFLYDAGEFDAAFFGISPREALAM 1680 Query: 1645 EPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITG 1704 +PQQRL+LETVWE +E AG AP L SRTG F G YA LL D +E + G Sbjct: 1681 DPQQRLLLETVWELIESAGVAPDSLHRSRTGTFIGSNGQFYAPLLWNSGGD-LEGYQGVG 1739 Query: 1705 NALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSP 1764 NA + +SGRVA++LG EGPAV VDTACSS+LVA+H A QAL+ G+C LA+AGGV V+ +P Sbjct: 1740 NAGSVMSGRVAYSLGLEGPAVTVDTACSSSLVALHLAVQALRRGECSLAIAGGVTVMSTP 1799 Query: 1765 VTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASS 1824 + V SR + LS GRCK F ++ADG+ +EG L+++RLSDA R G RV AV+ S+ Sbjct: 1800 DSFVEFSRQQGLSEDGRCKAFASTADGFGLAEGVSALLVERLSDARRLGHRVLAVVRGSA 1859 Query: 1825 VNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXX 1884 VNQDGAS+GLT PNG +QQR+I A LA AGL+ ADVD +EAHGTGT LGDPIE Q Sbjct: 1860 VNQDGASNGLTAPNGPSQQRVIRAALADAGLAPADVDVVEAHGTGTRLGDPIEAQALLAT 1919 Query: 1885 XXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWD 1944 P+++GSVK+NIGHT++A+G AG++K+VL+L+ GV+P++LH + PSPH+ W Sbjct: 1920 YGQGRAGGRPVVLGSVKSNIGHTQAAAGVAGVMKMVLALERGVVPKTLHVDEPSPHVDWS 1979 Query: 1945 ALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXX 2004 A V + E VPW GRVRRAGVSSFG +GTNAHV+VEEAP + Sbjct: 1980 AGEVELAVEAVPWSRGGRVRRAGVSSFGISGTNAHVIVEEAPAE-------PEPEPGTRV 2032 Query: 2005 XGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALV 2064 D +S R AL E A R +S+T G + DV + RS FE+RA +V Sbjct: 2033 VAAGDLVVPWVVSGRDAGALREQAARLAAHVSST-GAGVVDVGWSLVATRSVFEHRAVMV 2091 Query: 2065 VDSVXXXXXXXXXXXXXXTPAGVVRG-EHVHRPTTAWLFTGQGSQYPGMARELFDTQPVF 2123 + GVV G ++F GQGSQ+ GMA L D PVF Sbjct: 2092 GSELDSMAESLAGFAAGGVVPGVVSGVAPAEGRRVVFVFPGQGSQWVGMAAGLLDACPVF 2151 Query: 2124 AQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAI 2183 A+ V +CA + + L++VL +L QPAL+AV + LAR W+ + + Sbjct: 2152 AEAVAECAAVLDPVTGWSLVEVLRGGGEA---VLGRVDVVQPALWAVMVSLARTWRYYGV 2208 Query: 2184 EPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQV 2243 EP V+GHS G+ AAACVAG SL DGAR++ R R + GG MV+V AE V + Sbjct: 2209 EPAAVVGHSQGEIAAACVAGGLSLADGARVVVLRSRAIARIAGGGGMVSVGLSAERVRTM 2268 Query: 2244 AGEF-PRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVL 2301 + RVSV A NGP +TV+SG + L+E++ E EG+R + +A HS +D + Sbjct: 2269 LDTYGGRVSVAAVNGPSSTVVSGDVQALDELLAGCEREGVRARRVPVDYASHSAQMDQLR 2328 Query: 2302 DXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALG 2361 D ++P T L T LDA YW + R+ V+F E+V + A G Sbjct: 2329 DELLEALADITPQHSSVPFFSTVTADWL-DTTALDAGYWFTNLRETVRFQEAVEGLVAQG 2387 Query: 2362 CSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF 2421 +E P PVL Q + SLR+ ++ +LA A+V G D+ Sbjct: 2388 MGAFVECSPHPVLVPGIEQTLDALDQNAAVLGSLRRDEGGLDRLLTSLAEAFVQGVPVDW 2447 Query: 2422 A-AVHRQPRRPVELPTYPFQRRRFWPKAS--------SIAVDGGTAAS-GILGSGKDLAS 2471 A R V+LPTYPFQR+ +WPK + +A G TAA +LG+ ++ Sbjct: 2448 THAFEGMTPRTVDLPTYPFQRQHYWPKPAPAPGANLGDVASVGLTAAGHPLLGAVVEMPD 2507 Query: 2472 GD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPAR--LKDVFFYEPII 2528 D + T ++S+++ PWLADH + G+V++PG + +A+ A L ++ P++ Sbjct: 2508 SDGLVLTGQISLRTHPWLADHEVLGSVLLPGTAFVELAVQAADRAGYDVLDELTLEAPLV 2567 Query: 2529 LPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGAD-WSLNAEGTV-----------DT 2576 LP++ +V+L L P++ S Q+HSRP G W+ +A G V + Sbjct: 2568 LPDRGGIQVRLALGPSEADGRRSLQLHSRPEEAAGFHRWTRHASGFVVPGGTGAARPTEP 2627 Query: 2577 AGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWL-GDGE 2635 AG P A A +PV +R R+ + +GP++ G L + W GD Sbjct: 2628 AGVWPPAGA----EPVALASDRYARL---------VERGYTYGPSFQG-LHTAWRHGD-- 2671 Query: 2636 AVGDILVGAELAEQLGSE--PMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQV 2693 D+ L E ++ +HP L+D + ++LP + V Sbjct: 2672 ---DVYAEVALPEGTPADGYALHPALLDAAVQAVGLGSFV-----EDPGQVYLPFLWSDV 2723 Query: 2694 TLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGL 2753 TL R + L D G + + ++ L R Sbjct: 2724 TLHATGATSLRVRVS------PAGPDTVALALADPAGAPVATVGALRLRTTSAAQLARA- 2776 Query: 2754 GGDATRLLYTLGW------------------HEVPPPPSADDAVGTWLIAGFDELAAKVP 2795 G A ++ + W +E A A GTW + G +VP Sbjct: 2777 RGSAEHAMFRVEWVEEGSAADRCRGGAGGTTYEGERAAEAGAAAGTWAVLG-----PRVP 2831 Query: 2796 GCV----------------PIDRNT--DLQVLGEVLSQAHARGAGFSGVVWRCATPGRKX 2837 V P D + DL LG+ + + S + G + Sbjct: 2832 AAVRTMGVDVVTALDTPDHPADPQSLADLAALGDTVPDVVVVTSLLSLASGADSPLGNR- 2890 Query: 2838 XXXXXXXXXXXXXXITNLLSAVHAA-------QGPSVKLPGGLWIVTEHGVACESGEP-V 2889 + + SA+HAA L +VT H + +P Sbjct: 2891 -PRPTAAEQDTAATVAGVHSALHAALDLVQAWLADERHTASRLVLVTRHAMTVAESDPEP 2949 Query: 2890 DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLL 2949 D + A +WG R+ E P L D DG + D E+A+R G + Sbjct: 2950 DLLLAPVWGLVRSAQAENPGRFV-LADIDGDEASWDALPRAVASAA---SEVAIRAGAVY 3005 Query: 2950 ASRLLPWARSGHLTLPR-GGDFVLAPTERGAIDNLRLTETDVPEPDEG------YVQVRV 3002 RL G + G + L TE G + NL L VP PD V++ V Sbjct: 3006 VPRLARATDEGLVVADEAAGPWRLDVTEAGTLANLAL----VPCPDASRPLGPDEVRIAV 3061 Query: 3003 EAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRF 3062 AAG+NFRDVL LG+YP D G +G + AG VT++G GV+ L G RV G + G F Sbjct: 3062 RAAGVNFRDVLLALGMYP-DEGLMGAEAAGVVTEVGGGVTTLAPGDRVMGLVTGGFGPVA 3120 Query: 3063 NVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGVGLAAIQ 3121 + L +P G EAA++P A LT A D A L+ G+ VL+H+A+GGVG+AA+Q Sbjct: 3121 VTHHRMLVRMPRGWSFAEAASVPVAFLTAYYALHDLAGLRGGESVLVHSAAGGVGMAAVQ 3180 Query: 3122 MAQQSGAEVFATASTFKRSTLRRLGV--KYVYDSRTTDFADQILADTNGAGVDVVLNSLT 3179 +A+ AEVF TAS K L G+ +++ SRTT+F + A + G G+DVVLN+L Sbjct: 3181 LARHWDAEVFGTASKGKWDVLAAQGLDEEHIGSSRTTEFEQRFRATSGGRGIDVVLNAL- 3239 Query: 3180 SAGFVEATLKATAQGGRFAEIAKRDIWSHEQM--AEARPDIAYEIVALDTVMFTEPDRIR 3237 S FV+A+ + +GGRF E+ K DI + + A+ PDI Y VA D + +RI Sbjct: 3240 SGDFVDASARLLREGGRFVEMGKTDIRTDLGVVGADGVPDIRY--VAFD-LAEAGAERIG 3296 Query: 3238 DLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSY 3297 +L E+ G P +P+ A A R + QARH+GK+ + + Sbjct: 3297 QMLDEIMALFDAGVLRLPPLRAWPVRRAHEALRFVSQARHVGKV--VLTVPAALDAEGTV 3354 Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRD--PDESAQRAIDEITERHKCRIHTYAA 3354 LITG G +G A +L + ++L SR PD +A+ + A Sbjct: 3355 LITGA-GTLGALVARHLVTEHDVRRLLLVSRSGVAPDLAAELG------ALGAEVTVAAC 3407 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGA--SH 3412 DV + + LL I E P+ GI H AGVLDD ++S PER T L PK A Sbjct: 3408 DVANRKALKALLEDIPPE-HPVTGIVHTAGVLDDGVVSGLTPERVDTVLKPKVDAALTLE 3466 Query: 3413 XXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPW 3472 PGQ +YA AN LD L R +GL + + +G W Sbjct: 3467 SVIGELDLDPALFVIFSSAASMLGGPGQGSYAAANQFLDTLARHRARRGLTSVSLGWGLW 3526 Query: 3473 GQ-----GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAA- 3526 + GG+A + ++ G+ P+ ALH A G +L AA Sbjct: 3527 HEASGLTGGLADID--RDRMSRAGIAPMPTDEALHLFDR--ATELGDPVLLPMRLNEAAL 3582 Query: 3527 --KVLGSARPPILDLVL-----PSA------AGEATGDSELLKQLMEIPIPQRAGFVTEF 3573 + PP+L ++ PSA A ATG ++L P P+RA + + Sbjct: 3583 EDRAADGTLPPLLSGLVRVRHRPSARAGTATAAPATGPEAFARELAAAPDPRRA--LRDL 3640 Query: 3574 LQREVQNFLRLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPT 3631 ++ V L + P A A F D+G DSL A+ELRNRL+++ G + T VFDYP Sbjct: 3641 VRGHVALVLGHSGPEAIDAEQAFRDIGFDSLTAVELRNRLNAETG--LRLPGTLVFDYPN 3698 Query: 3632 IGGLAEYLVGQLPDAEAPETA 3652 LA++L+ L A P A Sbjct: 3699 PSALADHLLELLAPATQPTAA 3719 Score = 632 bits (1630), Expect = e-178 Identities = 382/908 (42%), Positives = 514/908 (56%), Gaps = 23/908 (2%) Query: 1559 DDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTY 1616 D+PIA+ +++C FPG PE WELL+ G + + E P+DR WD+DE Y PDP+ G +Y Sbjct: 30 DEPIAITSMACHFPGGIESPEQLWELLSAGGEVLSEFPDDRGWDLDEIYHPDPEHSGTSY 89 Query: 1617 TRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGV 1676 R +FFGISPREA+ ++PQQRL+LET W+ ERAG P L+GSRTGV Sbjct: 90 VRHGGFLDHATQFDTDFFGISPREALAMDPQQRLLLETSWQLFERAGVDPHTLKGSRTGV 149 Query: 1677 FTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALV 1736 F G A YA + + E + +TGNA +SGR+++ G EGPAV VDTACSS+LV Sbjct: 150 FVGAAHMGYADRVDTPPAE-AEGYLLTGNASAVVSGRISYTFGLEGPAVTVDTACSSSLV 208 Query: 1737 AVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSE 1796 A+H A QAL+ G+C LA+ GGV V+ P V SR R L+ GR K F ASADG+ +E Sbjct: 209 ALHLAVQALRRGECSLAVVGGVAVMSDPKVFVEFSRQRGLARDGRSKAFAASADGFGFAE 268 Query: 1797 GCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLS 1856 G +L+L+RLSDA R G RV AV+ S+VNQDGAS+GL PNG +QQR+I A LA AGL+ Sbjct: 269 GVSLLLLERLSDARRLGHRVLAVVRGSAVNQDGASNGLAAPNGPSQQRVIRAALADAGLA 328 Query: 1857 GADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGL 1916 ADVD +EAHGTGT LGDPIE Q P+ +GSVK+NIGHT++A+G AG+ Sbjct: 329 PADVDVVEAHGTGTRLGDPIEAQALLATYGQGRTSGRPVWLGSVKSNIGHTQAAAGVAGV 388 Query: 1917 IKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNG-RVRRAGVSSFGFTG 1975 +K+VL+L+ GV+P++LH + PSPH+ W V ++ E PW+ R+RRAG+S+FG +G Sbjct: 389 MKMVLALERGVVPKTLHVDEPSPHVDWSTGAVELLTEERPWEPEAERLRRAGISAFGVSG 448 Query: 1976 TNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWL 2035 TNAHV+VEEAP + D +S R AL A R + Sbjct: 449 TNAHVIVEEAPAE-----PEPEPEPGTRVVAAGDLVVPWVVSGRDAGALRAQAARLAAHV 503 Query: 2036 SATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRG-EHVH 2094 S+T G + DV + RS FE+RA +V + GVV G Sbjct: 504 SST-GAGVVDVGWSLVATRSVFEHRAVMVGTDLDSMAGSLAGFAAGGVVPGVVSGVAPAE 562 Query: 2095 RPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETA 2154 ++F GQGSQ+ GMA L D PVFA+ V +CA + + L++VL R Sbjct: 563 GRRVVFVFPGQGSQWVGMAAGLLDACPVFAEAVAECAAVLDPLTGWSLVEVL----RGGE 618 Query: 2155 DLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLM 2214 +L QPAL+AV + LAR W+ + +EP V+GHS G+ AAACVAG SL DGAR++ Sbjct: 619 AVLGRVDVVQPALWAVMVSLARTWRYYGVEPAAVVGHSQGEIAAACVAGGLSLADGARVV 678 Query: 2215 AERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF-PRVSVGAYNGP-NTVLSGPGEDLEEI 2272 R R + GG MV+V A V + + R+SV A NGP +TV+SG + L+E+ Sbjct: 679 VLRSRAIARIAGGGGMVSVSLPAGRVRTMLDTYGGRLSVAAVNGPSSTVVSGDAQALDEL 738 Query: 2273 VERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQ 2332 + E EG+R + +A HS +D + D ++P T L Sbjct: 739 LAGCEREGVRARRVPVDYASHSAQMDQLRDELLEALADITPQHSSVPFFSTVTADWL-DT 797 Query: 2333 TPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAV 2392 T LDA YW + R+ V+F E+V + A G +E P PVL Q A A+ Sbjct: 798 TALDAGYWFTNLRETVRFQEAVEGLVAQGMGAFVECSPHPVLVPGIEQTLDTVEADAVAL 857 Query: 2393 ASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFW----PK 2447 SLR+ + +LA A+V G D++ R V+LPTYPFQR+RFW P Sbjct: 858 GSLRRDEGGLGRFLTSLAEAFVQGVPVDWSRTFEGASPRTVDLPTYPFQRQRFWLEGSPA 917 Query: 2448 ASSIAVDG 2455 SS V+G Sbjct: 918 LSSNGVEG 925 Score = 118 bits (295), Expect = 2e-23 Identities = 126/420 (30%), Positives = 175/420 (41%), Gaps = 43/420 (10%) Query: 1176 PLPVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYA 1234 P + + T L+TG G +G VA +L + H ++L SR Sbjct: 3345 PAALDAEGTVLITGA-GTLGALVARHLVTEHDVRRLLLVSRS----GVAPDLAAELGALG 3399 Query: 1235 CDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGK 1294 +V V DVA+ + L+ + E P+ GIVH AG + +SGL VD V K Sbjct: 3400 AEVTVAACDVANRKALKALLEDIPPE-HPVTGIVHTAGVLDDGVVSGLTPERVDTVLKPK 3458 Query: 1295 VWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTA 1354 V A L + +L D FV SS AS+ GG GQ +Y AAN FLD LA RG+T+ Sbjct: 3459 VDAALTLESVIGELDLDPALFVIFSSAASMLGGPGQGSYAAANQFLDTLARHRARRGLTS 3518 Query: 1355 VSVNFGPW------AAGMADAESRARLEQRGVRTLSPAEAL------AGMADVVAGPVQG 1402 VS+ +G W G+AD + R R+ + G+ + EAL + D V P++ Sbjct: 3519 VSLGWGLWHEASGLTGGLADID-RDRMSRAGIAPMPTDEALHLFDRATELGDPVLLPMRL 3577 Query: 1403 VVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXX------LVEQLT 1456 A ++ L L S L +L Sbjct: 3578 NEAALE---------DRAADGTLPPLLSGLVRVRHRPSARAGTATAAPATGPEAFARELA 3628 Query: 1457 KAPVQQRKSLITNYLRNAVAEVTRVDADEIRD-EAGFFDLGMDSLMAVELRRRIEQGVGK 1515 AP +R + + +R VA V E D E F D+G DSL AVELR R+ G Sbjct: 3629 AAPDPRRA--LRDLVRGHVALVLGHSGPEAIDAEQAFRDIGFDSLTAVELRNRLNAETGL 3686 Query: 1516 DIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP 1575 +P TLV D+P S AD+LL E+L Q R + ++ A PG P Sbjct: 3687 RLPGTLVFDYPNPSALADHLL-ELLAPATQPTAAPLLAELERVEQLLSAAA----SPGGP 3741 >tr|Q52V53|Q52V53_9ACTO Tax_Id=255848 SubName: Full=Polyketide synthase type I;[Streptomyces aizunensis] Length = 5207 Score = 1651 bits (4275), Expect = 0.0 Identities = 1125/3019 (37%), Positives = 1534/3019 (50%), Gaps = 173/3019 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G R+PG S EE W L+ DG +AIS P DR WD+E + PDP PG + Sbjct: 37 AIVGMGCRYPGGVTSPEELWQLVVDGGDAISGFPADRGWDMETVYHPDPEHPGTSYANQG 96 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GFV D FD FG+S RE MDPQ R+L+ET+W A E +GI PTS+ GVFVG Sbjct: 97 GFVRDFARFDPSLFGISPREALAMDPQQRLLLETSWEAFERAGIDPTSMRGKQVGVFVGT 156 Query: 133 ATHDYLG--MASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVA 190 + HDYL ++S E +E Y+ G + + A+GR+SY GL+GPAV VDTACSSS VA Sbjct: 157 SNHDYLSALLSSSE----NVEGYLGTGNAASVASGRLSYTFGLEGPAVTVDTACSSSSVA 212 Query: 191 IHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG 250 +H A QALR EC LALAGGA ++ P T I +S LA DGRCK F ADG+ EG Sbjct: 213 LHLAVQALRNGECSLALAGGATLMSAPGTFIDYSKQRGLATDGRCKAFSPDADGFSLAEG 272 Query: 251 CGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRP 310 G+++V+RL DA R G + AV+RG+A+NQDGAS GLT PNG +QQRVI AL A L P Sbjct: 273 VGILLVERLSDARRKGHPVLAVVRGTAVNQDGASNGLTAPNGPSQQRVILQALSNARLTP 332 Query: 311 ADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXX 370 V +EAHGTGT LGDPIEAQA G R PL +GS KTNIGH + Sbjct: 333 DQVDAVEAHGTGTGLGDPIEAQALIATYGQDRPDGRPLWLGSLKTNIGHAQAAAGVAGVI 392 Query: 371 XXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTN 430 + + LP+ L+ + P+P + W + ++ E PW +PR GVSSFG +GTN Sbjct: 393 KSVMAMRHGVLPRTLHVDEPTPEVDWSAGDVSLLTEARPWPLGDQPRRIGVSSFGMSGTN 452 Query: 431 AHVILE-----------EAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDW 479 AH+ILE +A G T P V+ LS RT AL A Sbjct: 453 AHIILESAQEYADGRQADAGTAGNEPATGRTNPPGALPVV-LSGRTEPALRAQAAALHAH 511 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 L AHP +AD++ + RA L++RAA+V + R++ + L ALA+ RP+ +V G + + Sbjct: 512 LAAHPGLGIADLAFSQALTRAALDRRAAVVADDRDALLAGLAALAEGRPSADVVEGSATD 571 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 K A+LFTGQGSQ PGM REL+ T PVFA+ + +AV + LE PL DV+F D G Sbjct: 572 G-KLAFLFTGQGSQRPGMGRELYATYPVFAQAL----DAVCERLELPLKDVLFGTD---G 623 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 + L T Y QPALFAVE+ L RL +SWG +PD + GHS+G+ +AA VAGVF +ED Sbjct: 624 AAGAALDETAYTQPALFAVEVALFRLVESWGLKPDYLAGHSIGEIAAAHVAGVFSLEDAC 683 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLES 719 L+ RGRL +LP GG M AV + + L ++ +S+AA NG +V+ +D Sbjct: 684 TLVEARGRLMQALPTGGVMIAVEASEDEVLPLLTDW--VSIAAVNGPRSVVVAGDEDAAV 741 Query: 720 AVA-TLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALG 778 A+A A G + L SHAFHS +D +LD F + AQ L Y P+ ++ N TG AL Sbjct: 742 AIAEAFAAQGRKTKKLTVSHAFHSPHMDGMLDAFRTVAQGLSYGTPRIPVVSNLTG-ALV 800 Query: 779 RSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQ 838 +W RH R+ V F +R L +E+GP VL+A L AT P+ Sbjct: 801 TDEMGSADFWVRHVREAVRFLDGIRWLESRGVTTYIELGPGGVLSA--LGQDCQTATGPR 858 Query: 839 VLA---SLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWF 894 A +LR + +T AVA A+ G PD+ F A++++LPTY F+ +W Sbjct: 859 AAAFLPALRTGRPEASSLTAAVAGAHVRGLSPDWTVRFAGTGAQRVELPTYAFQRELYWP 918 Query: 895 SDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALID--GETVDEQTLRVLNKLA 952 D ++A G + + +++ E+LAAL D G DE VL L+ Sbjct: 919 RD--PFTDPAESAHGGELGATDAKFWEVVDS---EDLAALADTLGVGGDEPLSSVLPALS 973 Query: 953 ARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFA----DALTA 1008 A H + R RY + W W+LV A +A ALTA Sbjct: 974 AWHRRHRDRDTVDGWRYRVTWKPLTDTTPASPSGH-WLLVVPTEHADAPWAVAAERALTA 1032 Query: 1009 GGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRT--- 1065 G V L + D A + A A AG A + LL ++ R Sbjct: 1033 RGVTVSTVVLDATLDDRAATARRIGEALAASAATDSAPAGAETLAGVFSLLALEERPHPA 1092 Query: 1066 -------LGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPE-QSCLWGFGRAAAL 1117 L L +A DA + +P+W T TD + Q+ +WG GR AAL Sbjct: 1093 DPALSAGLAATVALIQALGDAGVEAPLWAATCGAVSTGRTDRLSSTAQAQVWGLGRTAAL 1152 Query: 1118 ELPHIWGGLADLSGADTEWPRLIARITSPRDG------EDQIALRGDAVYAPRLVRRTGE 1171 ELP WGGL DL G E R R+ G ED +A+R V+ RL R T + Sbjct: 1153 ELPVRWGGLVDLPGTPDE--RAAGRLADVLGGLGGPGAEDHLAVRSTGVFVRRLARATRD 1210 Query: 1172 PSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXE 1231 T T L+TGG GA+G VA +LA GA H++L SRR P Sbjct: 1211 ERPTT-EWATTGTALITGGTGALGRHVARWLARTGAQHLLLVSRRGPEAEGADALAAELR 1269 Query: 1232 QYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVF 1291 +V + DVAD VA L+ T+ AE PL +VHAAG + G+ DA+ + Sbjct: 1270 ALGAEVTIAACDVADRDAVAALLATLPAE-HPLTNVVHAAGVLD----DGVLDAQTPQRL 1324 Query: 1292 AGKVWGAWHLSEALTDLRTDLDF--FVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRE 1349 AG + H ++ L +L DLD FV SS+A+V+G GQ Y AANA L+ LA + R Sbjct: 1325 AGVLRPKAHAAQVLHELTRDLDLSAFVLFSSVAAVFGAAGQANYAAANASLEALAEQRRA 1384 Query: 1350 RGVTAVSVNFGPWA-AGMADAESRA-RLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAK 1406 G+ A + +G WA GMA E A RL G+ L+P AL+ + + +VA Sbjct: 1385 DGLPATVLAWGAWAEGGMATDELVAERLRLAGLPALAPELALSALHRALTLDETASLVAD 1444 Query: 1407 IDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSL 1466 IDW R P +++L + QL AP +R L Sbjct: 1445 IDWERLAPGLTAVRPCPLIADLPEAVHALAGAEASTGPGAAADTFARQLADAPAGERDQL 1504 Query: 1467 ITNYLRNAVAEVTRVDADEIRDEAGFF-DLGMDSLMAVELRRRIEQGVGKDIPVTLVMDH 1525 ++R VA V E D F DLG DSL AVE+R + G +P TL+ D+ Sbjct: 1505 ALEFVRTQVAAVLGYAGPESVDPGSAFRDLGFDSLTAVEIRNLLTSRTGLRLPATLIFDY 1564 Query: 1526 PRLSDAADYLLVEVLGLGEQTNVRQ--ASTVTARTDDPIAVVAVSCRFPGA-PDPESFWE 1582 P A +L E+LG R A TA DDPIA+VA+SCRFPG PE W+ Sbjct: 1565 PNSLSLAAFLQGELLGAQATDPARHTPAGPGTATDDDPIAIVAMSCRFPGGVQSPEDLWQ 1624 Query: 1583 LLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREA 1641 LL+ G DAI P DR WD+D YDP+ +Y R P FFGISPREA Sbjct: 1625 LLSTGRDAISGFPGDRGWDLDGLYDPESAGENTSYVREGGFLAGATEFDPAFFGISPREA 1684 Query: 1642 VWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHF 1701 + ++PQQRL+LET WE ERAG P+ +RG + GVFTG +Y +++ A D +E Sbjct: 1685 LAMDPQQRLLLETSWEAFERAGIDPATVRGEQIGVFTGTNGQDYLNVILAAP-DGVEGFL 1743 Query: 1702 ITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVL 1761 TGNA + +SGRV++ LG EGPAV VDTACSS+LVA+H A QAL+ G+C +ALAGGV V+ Sbjct: 1744 GTGNAASVVSGRVSYVLGLEGPAVTVDTACSSSLVALHWAIQALRQGECTMALAGGVTVM 1803 Query: 1762 LSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIP 1821 +P + + SR R L+ GR K F A+ADG EG G+L+++RLSDA R+G V A++ Sbjct: 1804 STPASFIDFSRQRGLAEDGRIKAFAAAADGTGWGEGVGILLVERLSDAQRNGHPVLAIVR 1863 Query: 1822 ASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXX 1881 S++NQDGAS+GLT PNG +QQR+I LA GL+ DVD +EAHGTGT LGDPIE Q Sbjct: 1864 GSAINQDGASNGLTAPNGPSQQRVIRQALASGGLTTMDVDAVEAHGTGTKLGDPIEAQAL 1923 Query: 1882 XXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHI 1941 PLL+GS+K+N+GHT++A+G AG++K+VL++QHGVLPQ+LH + P+PH+ Sbjct: 1924 LATYGQDRPEGRPLLLGSIKSNLGHTQAAAGVAGVMKMVLAMQHGVLPQTLHVDEPTPHV 1983 Query: 1942 PWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXX 2001 W A V ++ + V W GR RRAGVSSFG +GTNAH ++E+AP + Sbjct: 1984 DWSAGDVALLADAVAWPETGRPRRAGVSSFGISGTNAHTIIEQAPAAV------APVPPV 2037 Query: 2002 XXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRA 2061 D PQ LSA++ +AL + ARR P L AD+ + GRS FE RA Sbjct: 2038 ATTPARADGPQPWLLSAKTRDALHDQARRLHAHAELNPELSPADLGLSLAAGRSAFERRA 2097 Query: 2062 ALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQP 2121 A++ AG+V G V A+LFTGQGSQ GM REL+DT P Sbjct: 2098 AVIAADRDGLLAGLAALADGGAAAGLVEGSPV-AGKLAFLFTGQGSQRLGMGRELYDTYP 2156 Query: 2122 VFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSW 2181 VFA + V L PL DVLF D LL T++ QPALFAVE+ L RL +SW Sbjct: 2157 VFADALDAVCAHVDAHLEVPLKDVLFGAD---TGLLDQTAYTQPALFAVEVALFRLVESW 2213 Query: 2182 AIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVE 2241 + PD + GHS+G+ AAA VAGVFSL D + L+ RGR+ +LP GG M+AV A + V Sbjct: 2214 GLRPDFLAGHSIGEIAAAHVAGVFSLQDASELVVARGRLMQALPTGGVMIAVQASEDEVL 2273 Query: 2242 QVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPV 2300 + + RVS+ A NGP + V++G D I E F G + L SHAFHS +D + Sbjct: 2274 PLLTD--RVSIAAINGPQSVVIAGDEADAVAIAESF--TGRKSKRLTVSHAFHSPHMDGM 2329 Query: 2301 LDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAAL 2360 L+ P +P+V N TGA+++ + A++W RH R+ V+F + +RT+ A Sbjct: 2330 LEDFRAVAEGLSYEAPRIPVVSNLTGALISDEMG-SAEFWVRHVREAVRFLDGIRTLEAA 2388 Query: 2361 GCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPD 2420 G + +E+GP VL+ A + + LRK + + AL +A+V G D Sbjct: 2389 GVTKYVELGPDGVLSAMAQDCVSGEGSV--FIPVLRKARPEPESVTTALTTAHVHGIPVD 2446 Query: 2421 FAAVHR-QPRRPVELPTYPFQRRRFWPKASSI------AVDGGTAASGILGSGKDLASGD 2473 + A R V+LPTY FQR+R+WP SS+ A+ A +L +G L D Sbjct: 2447 WQAFFAGTGARRVDLPTYAFQRQRYWPAVSSLYLGDVEAIGLDDTAHPLLSAGVALPESD 2506 Query: 2474 -TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIIL 2529 ++ RL++ + WLADH I G+V++PG + +A A VG L+++ P++L Sbjct: 2507 GMVFAGRLALSTHAWLADHAILGSVLLPGTAFVELATRAGDQVGCD-YLEELTLEAPLVL 2565 Query: 2530 PEKASREVQLTLHPADGGSVLSFQIHSRPYGERGAD-WSLNAEGTVDTAGSDPDAAADEQ 2588 PE ++++ + AD F +HSR G + W+ +A G + G P A D Sbjct: 2566 PEHGGVQLRVWVGAADESGRRPFALHSRAEGLPVEEPWTRHAGGVL-AEGGRPPADFDLT 2624 Query: 2589 SDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAE 2648 + P +E + ++ + A+GPT+ G L++ W DGE ++ + Sbjct: 2625 AWPPPGAVE----VDLDGRYDQLDGIGFAYGPTFRG-LRTAWQLDGEIYAEVRLPEGAEG 2679 Query: 2649 QLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRAR 2708 + G +HP L+D + LP + V+L R Sbjct: 2680 EAGRFGLHPALLDAALHAIGLGGLGADDGQGR-----LPFAWSGVSLHAGGA----AALR 2730 Query: 2709 WHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHE 2768 H + +E LE D G + + ++ E LR ++ W E Sbjct: 2731 VHLAPAGAEG--VRLEIADASGAPVAAVESLGLRPVTAEQ-LRAARATYHESVFRQQWTE 2787 Query: 2769 VP--PPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGV 2826 +P P+A AV + G + DR+ DL L + R V Sbjct: 2788 LPGLGAPAATPAVRYAFLGGDSGDSGDSGDTAAADRHQDLAALAAAIDA--GRPVPDEVV 2845 Query: 2827 VWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKL-----------PGGLWI 2875 V A P SAVH+A ++ L L Sbjct: 2846 VELAAAPWAVS------------------ASAVHSAAHDALALIQTWLADDRFAAARLVF 2887 Query: 2876 VTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXP 2934 +T VA ++G+ V D A +WG R+ E P LVD DG + Sbjct: 2888 LTRGAVAADAGDDVTDLAAATVWGLLRSAQTENPG-RIALVDTDGHDRSEQALRAALTS- 2945 Query: 2935 GIQEPEIAVRQGKLLASRL 2953 E A+R G +L RL Sbjct: 2946 --DEERFALRAGAVLVPRL 2962 Score = 907 bits (2343), Expect = 0.0 Identities = 695/2007 (34%), Positives = 965/2007 (48%), Gaps = 143/2007 (7%) Query: 1007 TAGGHRHQIVALPGSDADEAQ------LVDTLRAASAGELYVVHIAAGDGAAAPMRDLLR 1060 TA RHQ +A + D + +V+ A A VH AA D A A ++ L Sbjct: 2818 TAAADRHQDLAALAAAIDAGRPVPDEVVVELAAAPWAVSASAVHSAAHD-ALALIQTWLA 2876 Query: 1061 VQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELP 1120 L L R A A+ G VTD +WG R+A E P Sbjct: 2877 DDRFAAARLVFLTRGAVAADA----------GDDVTDLAAAT-----VWGLLRSAQTENP 2921 Query: 1121 HIWGGLADLSGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSD---TPL 1177 L D G D L A +TS E++ ALR AV PRL R + D TP Sbjct: 2922 GRIA-LVDTDGHDRSEQALRAALTSD---EERFALRAGAVLVPRLARVEIQQDDSARTPA 2977 Query: 1178 PVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACD 1236 + T L+TG GA+G A +LA+ HG ++L RR + Sbjct: 2978 -LTPGGTVLITGATGALGGLFARHLAAEHGVERLLLVGRRGADAPGAAELVAELAESGTL 3036 Query: 1237 VRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVW 1296 DVAD +A L+ + AE PL +VH AG + +S L + V KV Sbjct: 3037 ATWAACDVADRDALAALLADIPAE-HPLTAVVHTAGVLDDGVISSLTPERLSAVLRPKVD 3095 Query: 1297 GAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVS 1356 AW+L E L DL FV SS + ++GG GQ Y AAN+FLD LA R G+ A S Sbjct: 3096 AAWNLHELTRGL--DLAAFVLFSSTSGLFGGPGQGNYAAANSFLDALAQHRRAHGLPATS 3153 Query: 1357 VNFGPWA-----AGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGVVA--KIDW 1409 +G W+ AG DA R+ + G+ L+ A+ L G+ D + +A ++D Sbjct: 3154 TAWGLWSVADGMAGALDAADVNRMRRAGLPPLTAADGL-GLFDTAVSLDEASLALMRVD- 3211 Query: 1410 SRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITN 1469 + L AG A L L +L ++ + + Sbjct: 3212 TEVLRTQAGAGTIAPLLRGLVRGVARRSVDVSAGAGGAESELRGRLAALTAAEQDRALLD 3271 Query: 1470 YLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRL 1528 +R VA V + F +LG DSL AVELR R+ +P TL+ D+P Sbjct: 3272 LVRTQVAAVLGHAGPAAVESGRAFKELGFDSLTAVELRNRLNAATALRLPATLIFDYPDP 3331 Query: 1529 SDAADYLLVEVLGLGEQTNVRQASTVTARTDD-PIAVVAVSCRFPG-APDPESFWELLAG 1586 + A YL E++G + T A +TA DD PIA+VA+SCR+PG PE W+LL Sbjct: 3332 TVLARYLRGELIG--DDTTDAVAEPLTAVADDEPIAIVAMSCRYPGDVRTPEDLWQLLTA 3389 Query: 1587 GVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIE 1645 G D I +PE+R WD + YDPDP++ G +Y R FFGISPREA+ ++ Sbjct: 3390 GADGITRLPENRGWDTEGLYDPDPESQGTSYARDGGFLHDAAEFDASFFGISPREALAMD 3449 Query: 1646 PQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGN 1705 PQQRL+LET WE ERAG APS +RGSRTGVF GV ++Y L A D +E + TG+ Sbjct: 3450 PQQRLLLETTWEVFERAGIAPSAVRGSRTGVFAGVMYHDYGARLHAVP-DGVEGYLGTGS 3508 Query: 1706 ALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPV 1765 + + +SGRVA+ G EGPAV VDTACSS+LVA+H A QAL++G+C LALAGGV V+ +P Sbjct: 3509 SSSIVSGRVAYTFGLEGPAVTVDTACSSSLVALHLAAQALRNGECSLALAGGVTVMFTPG 3568 Query: 1766 TVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSV 1825 T + SR R L+ GRCK+F A+ADG EG G+L+L+RLSDA R+G +V AV+ S+V Sbjct: 3569 TFIEFSRQRGLAADGRCKSFAAAADGTGWGEGAGMLLLERLSDARRNGHQVLAVVRGSAV 3628 Query: 1826 NQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXX 1885 NQDGAS+GLT PNG +QQR+I LA AG++ VD +EAHGTGT LGDPIE Q Sbjct: 3629 NQDGASNGLTAPNGPSQQRVIRQALANAGVAAGHVDAVEAHGTGTTLGDPIEAQALLATY 3688 Query: 1886 XXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDA 1945 PLL+GSVK+N+GHT++ASG AG+IK+V+S++HGVLP++LH + P+PH+ W A Sbjct: 3689 GQEHTDDRPLLLGSVKSNLGHTQAASGVAGVIKMVMSMRHGVLPKTLHVDEPTPHVDWSA 3748 Query: 1946 LPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXX 2005 V ++ E PW GR RRAGVSSFG +GTNAH ++E+AP Sbjct: 3749 GAVSLLTEQTPWPETGRPRRAGVSSFGISGTNAHAIIEQAP---EPDPARAKATARPAPD 3805 Query: 2006 GTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVV 2065 S L +SAR +AL ARR + A PGL D+ + RS E RAALV Sbjct: 3806 AAAPSSVPLIVSARGEDALRAQARRLHAHVHADPGLRAVDLGLSLATTRSALEQRAALVA 3865 Query: 2066 DSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQ 2125 AG+VRG A+LFTGQGSQ PGM REL+D PVFA Sbjct: 3866 GDRAELLRGLDALARGEDTAGLVRGT-AREGQVAFLFTGQGSQRPGMGRELYDAHPVFAD 3924 Query: 2126 TVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEP 2185 + + + L PL VLFAT+ DL+ T++ QPALFAVE+ L RL +S ++P Sbjct: 3925 ALDEICGELDRHLEVPLKGVLFATE---GDLIHQTAYTQPALFAVEVALFRLLESRGVQP 3981 Query: 2186 DVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAG 2245 D + GHS+G+ AAA VAGVFSL D + L+A RGR+ +LP GG M+AV A + V + Sbjct: 3982 DFLAGHSIGEIAAAHVAGVFSLQDASELVAARGRLMQALPTGGVMIAVQASEDEVLPLLT 4041 Query: 2246 EFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXX 2304 + RVS+ A NGP + V++G D I E F D + L SHAFHS +D +L Sbjct: 4042 D--RVSIAAINGPQSVVIAGDEADAVAIAESFTDR--KSKRLTVSHAFHSPHMDGMLADF 4097 Query: 2305 XXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSV 2364 P +P+V N TGA++T + A +W RH R+ V+F + +R + A G + Sbjct: 4098 RKVAEGLVYENPRIPVVSNLTGALVTDEMG-SADFWVRHVREAVRFLDGIRALEAAGVTT 4156 Query: 2365 LMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAV 2424 +E+GP VL A + V LR G + + ALA +V G D+ A Sbjct: 4157 HIELGPDGVLCAMAQECVSGEDTV--FVPVLRPGRPEAETVTTALARVHVQGVPVDWQAY 4214 Query: 2425 HR-QPRRPVELPTYPFQRRRFWPKASSIAVDGGTAASGILGSGKDLA------------- 2470 + V+LPTY FQR+R+W +D G + +L +G D A Sbjct: 4215 FSGTGAQRVDLPTYAFQRKRYW-------LDVGVSVEDVLAAGLDAADHPLLGATVSLPG 4267 Query: 2471 SGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPI 2527 S + T RL++ + PWL+DH + TV++PG + +AL A VG A ++++ P+ Sbjct: 4268 SDGLVLTGRLALSTHPWLSDHTVMDTVLLPGTAFVELALRAGELVGCGA-VEELALEAPL 4326 Query: 2528 ILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGAD-WSLNAEGTVDTAGS------- 2579 L ++ + + QL + DG + +HSR G + W+ +A G + S Sbjct: 4327 TLADQGAVQFQLAVDAPDGAGRRTLTLHSRRAGAPAEEPWTRHATGVLTPEASAVPAHPF 4386 Query: 2580 DPDAAADEQSDPVDEVIERLERMRPQDLF-ETFADLELAWGPTWSGSLKSLWLGDGEAVG 2638 D A ++PV P D F A L +GP + G L++ W E Sbjct: 4387 DLTAWPPADAEPV-----------PTDAFYPGAAAAGLGYGPVFQG-LRAAWRRGDELFA 4434 Query: 2639 DILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEK 2698 ++ + E + +HP L+D P ++ A Sbjct: 4435 EVALDEEHEADAAAYGLHPALLDAALHAIGLGAPGAPAD--------APAEGARLPFAWT 4486 Query: 2699 MPRRFYCRARWHRSALDSETQ-VFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDA 2757 R + A R L + L+ D G + + ++ E LGGD Sbjct: 4487 GVRLYAAGAAGIRVRLTAAASGGIALDVADSTGAPVASVESLILRPVSAEQ----LGGDR 4542 Query: 2758 T---RLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLS 2814 T L+ + W + P A + W + G DE +V G +D + L L E ++ Sbjct: 4543 TAHHESLFGVEWTRLSLPTGAIPSGERWAVLGEDEPDLRVGG-ERLDVYSGLTALREEIA 4601 Query: 2815 QAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGG-L 2873 A V A G + L+ +L G L Sbjct: 4602 -AGTSAPDVVVVPLSSAASGGGRAGTARAAAHHALALVKEWLA--------DERLDGARL 4652 Query: 2874 WIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXX 2932 ++T VA E V D A +WG R+ +E P L D DG+ + Sbjct: 4653 VLLTRGAVAAVPDEHVTDLTHAPVWGLVRSAQSENPGRFV-LADTDGADASFGALAAAL- 4710 Query: 2933 XPGIQEPEIAVRQGKLLASRLLPWARS 2959 EP++A+R G+ A RL AR+ Sbjct: 4711 --ATDEPQLALRSGEAHAFRLRRIART 4735 Score = 673 bits (1737), Expect = 0.0 Identities = 394/927 (42%), Positives = 534/927 (57%), Gaps = 28/927 (3%) Query: 1533 DYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAI 1591 DYL + L QT R V A+ DPIA+V + CR+P G PE W+L+ G DAI Sbjct: 9 DYLKLVTADL-HQTRQRLRD-VEAKNQDPIAIVGMGCRYPGGVTSPEELWQLVVDGGDAI 66 Query: 1592 REVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRL 1650 P DR WD++ Y PDP+ PG +Y P FGISPREA+ ++PQQRL Sbjct: 67 SGFPADRGWDMETVYHPDPEHPGTSYANQGGFVRDFARFDPSLFGISPREALAMDPQQRL 126 Query: 1651 MLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAI 1710 +LET WE ERAG P+ +RG + GVF G + ++Y L + S + +E + TGNA + Sbjct: 127 LLETSWEAFERAGIDPTSMRGKQVGVFVGTSNHDYLSALLSSS-ENVEGYLGTGNAASVA 185 Query: 1711 SGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAA 1770 SGR+++ G EGPAV VDTACSS+ VA+H A QAL++G+C LALAGG ++ +P T + Sbjct: 186 SGRLSYTFGLEGPAVTVDTACSSSSVALHLAVQALRNGECSLALAGGATLMSAPGTFIDY 245 Query: 1771 SRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGA 1830 S+ R L+ GRCK F ADG+ +EG G+L+++RLSDA R G V AV+ ++VNQDGA Sbjct: 246 SKQRGLATDGRCKAFSPDADGFSLAEGVGILLVERLSDARRKGHPVLAVVRGTAVNQDGA 305 Query: 1831 SSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXX 1890 S+GLT PNG +QQR+I L+ A L+ VD +EAHGTGT LGDPIE Q Sbjct: 306 SNGLTAPNGPSQQRVILQALSNARLTPDQVDAVEAHGTGTGLGDPIEAQALIATYGQDRP 365 Query: 1891 XXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRV 1950 PL +GS+KTNIGH ++A+G AG+IK V++++HGVLP++LH + P+P + W A V + Sbjct: 366 DGRPLWLGSLKTNIGHAQAAAGVAGVIKSVMAMRHGVLPRTLHVDEPTPEVDWSAGDVSL 425 Query: 1951 IDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDS 2010 + E PW + RR GVSSFG +GTNAH+++E A G + Sbjct: 426 LTEARPWPLGDQPRRIGVSSFGMSGTNAHIILESAQEYADGRQADAGTAGNEPATGRTNP 485 Query: 2011 PQVL--ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSV 2068 P L LS R+ AL A L+A PGL IAD+ + + R+ + RAA+V D Sbjct: 486 PGALPVVLSGRTEPALRAQAAALHAHLAAHPGLGIADLAFSQALTRAALDRRAAVVADDR 545 Query: 2069 XXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVR 2128 A VV G A+LFTGQGSQ PGM REL+ T PVFAQ + Sbjct: 546 DALLAGLAALAEGRPSADVVEGSATD-GKLAFLFTGQGSQRPGMGRELYATYPVFAQAL- 603 Query: 2129 QCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVV 2188 +AV + L PL DVLF TD L T++ QPALFAVE+ L RL +SW ++PD + Sbjct: 604 ---DAVCERLELPLKDVLFGTDGAAGAALDETAYTQPALFAVEVALFRLVESWGLKPDYL 660 Query: 2189 LGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFP 2248 GHS+G+ AAA VAGVFSL+D L+ RGR+ +LP GG M+AV A + V + ++ Sbjct: 661 AGHSIGEIAAAHVAGVFSLEDACTLVEARGRLMQALPTGGVMIAVEASEDEVLPLLTDW- 719 Query: 2249 RVSVGAYNGPNTVLSGPGEDLE-EIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXX 2307 VS+ A NGP +V+ ED I E F +G + L SHAFHS +D +LD Sbjct: 720 -VSIAAVNGPRSVVVAGDEDAAVAIAEAFAAQGRKTKKLTVSHAFHSPHMDGMLDAFRTV 778 Query: 2308 XXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLME 2367 P +P+V N TGA++T + A +W RH R+ V+F + +R + + G + +E Sbjct: 779 AQGLSYGTPRIPVVSNLTGALVTDEMG-SADFWVRHVREAVRFLDGIRWLESRGVTTYIE 837 Query: 2368 IGPQPVLTGAAVQVWPEHMAAPRAVA---SLRKGVADRRQIADALASAYVGGHRPD---- 2420 +GP VL+ + PRA A +LR G + + A+A A+V G PD Sbjct: 838 LGPGGVLSALGQDC--QTATGPRAAAFLPALRTGRPEASSLTAAVAGAHVRGLSPDWTVR 895 Query: 2421 FAAVHRQPRRPVELPTYPFQRRRFWPK 2447 FA Q VELPTY FQR +WP+ Sbjct: 896 FAGTGAQ---RVELPTYAFQRELYWPR 919 Score = 659 bits (1700), Expect = 0.0 Identities = 386/889 (43%), Positives = 513/889 (57%), Gaps = 27/889 (3%) Query: 15 AIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + R+PG + E+ W LL G + I+ +P++R WD E +DPDP + G R Sbjct: 3365 AIVAMSCRYPGDVRTPEDLWQLLTAGADGITRLPENRGWDTEGLYDPDPESQGTSYARDG 3424 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE MDPQ R+L+ET W E +GIAP+++ S TGVF G+ Sbjct: 3425 GFLHDAAEFDASFFGISPREALAMDPQQRLLLETTWEVFERAGIAPSAVRGSRTGVFAGV 3484 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 HDY A +E Y+ G+S++ +GR++Y GL+GPAV VDTACSSSLVA+H Sbjct: 3485 MYHDY--GARLHAVPDGVEGYLGTGSSSSIVSGRVAYTFGLEGPAVTVDTACSSSLVALH 3542 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC LALAGG V+ TP T I FS LA DGRCK+F AAADG GEG G Sbjct: 3543 LAAQALRNGECSLALAGGVTVMFTPGTFIEFSRQRGLAADGRCKSFAAAADGTGWGEGAG 3602 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++++RL DA R+G ++ AV+RGSA+NQDGAS GLT PNG +QQRVI AL AG+ Sbjct: 3603 MLLLERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGVAAGH 3662 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT+LGDPIEAQA G + PLL+GS K+N+GH + Sbjct: 3663 VDAVEAHGTGTTLGDPIEAQALLATYGQEHTDDRPLLLGSVKSNLGHTQAASGVAGVIKM 3722 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LPK L+ + P+PH+ W + ++ E PW G+PR AGVSSFG +GTNAH Sbjct: 3723 VMSMRHGVLPKTLHVDEPTPHVDWSAGAVSLLTEQTPWPETGRPRRAGVSSFGISGTNAH 3782 Query: 433 VILEEAP---AVGTPATTEPVEDPRRYSVLPL--SARTPEALVRLAGEYRDWLRAHPQAR 487 I+E+AP AT P D S +PL SAR +AL A + A P R Sbjct: 3783 AIIEQAPEPDPARAKATARPAPDAAAPSSVPLIVSARGEDALRAQARRLHAHVHADPGLR 3842 Query: 488 LADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLF 547 D+ + T R+ LEQRAALV R + L ALA GLVRG + E + A+LF Sbjct: 3843 AVDLGLSLATTRSALEQRAALVAGDRAELLRGLDALARGEDTAGLVRGTAREG-QVAFLF 3901 Query: 548 TGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRH 607 TGQGSQ PGM REL+D PVFA+ + + + LE PL V+F TE L H Sbjct: 3902 TGQGSQRPGMGRELYDAHPVFADALDEICGELDRHLEVPLKGVLF-------ATEGDLIH 3954 Query: 608 -TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERG 666 T Y QPALFAVE+ L RL +S G +PD + GHS+G+ +AA VAGVF ++D + L+A RG Sbjct: 3955 QTAYTQPALFAVEVALFRLLESRGVQPDFLAGHSIGEIAAAHVAGVFSLQDASELVAARG 4014 Query: 667 RLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLV 725 RL +LP GG M AV + + LTD +S+AA NG +V+ + A+A Sbjct: 4015 RLMQALPTGGVMIAVQASEDEVLPLLTDR---VSIAAINGPQSVVIAGDEADAVAIAESF 4071 Query: 726 ADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDG 785 D + L SHAFHS +D +L DF A+ L Y P+ ++ N TG AL Sbjct: 4072 TDR-KSKRLTVSHAFHSPHMDGMLADFRKVAEGLVYENPRIPVVSNLTG-ALVTDEMGSA 4129 Query: 786 AYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRP 845 +W RH R+ V F +R L +E+GP VL A A T + LRP Sbjct: 4130 DFWVRHVREAVRFLDGIRALEAAGVTTHIELGPDGVLCAMAQECVSGEDTV--FVPVLRP 4187 Query: 846 TTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFW 893 + +T A+A + G D++A F A+++DLPTY F+ +++W Sbjct: 4188 GRPEAETVTTALARVHVQGVPVDWQAYFSGTGAQRVDLPTYAFQRKRYW 4236 Score = 197 bits (502), Expect = 2e-47 Identities = 134/367 (36%), Positives = 175/367 (47%), Gaps = 15/367 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G H A +LA+ GA ++L SRR P+ A+ + A DV Sbjct: 1224 LITGGTGALGRHVARWLARTGAQHLLLVSRRGPEAEGADALAAELRALGAEVTIAACDVA 1283 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D VA LLA + AE PL + H AGVLDD +L AQ P+R L PKA+ A Sbjct: 1284 DRDAVAALLATLPAE-HPLTNVVHAAGVLDDGVLDAQTPQRLAGVLRPKAHAAQVLHELT 1342 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQANYA ANA L+ L +RRA GL AT + +G W +GGM Sbjct: 1343 RDLDLSAFVLFSSVAAVFGAAGQANYAAANASLEALAEQRRADGLPATVLAWGAWAEGGM 1402 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 A+ E + GL L P AL AL + + V +W+R A L + RP L Sbjct: 1403 ATDELVAERLRLAGLPALAPELALSALHRALTLDETASLVADIDWERLAPGLTAVRPCPL 1462 Query: 3538 DLVLPSA----------AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 LP A G +QL + P +R EF++ +V L A P Sbjct: 1463 IADLPEAVHALAGAEASTGPGAAADTFARQLADAPAGERDQLALEFVRTQVAAVLGYAGP 1522 Query: 3588 PAA--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPD 3645 + S F DLG DSL A+E+RN L S+ G + AT +FDYP LA +L G+L Sbjct: 1523 ESVDPGSAFRDLGFDSLTAVEIRNLLTSRTG--LRLPATLIFDYPNSLSLAAFLQGELLG 1580 Query: 3646 AEAPETA 3652 A+A + A Sbjct: 1581 AQATDPA 1587 Score = 163 bits (413), Expect = 4e-37 Identities = 186/598 (31%), Positives = 255/598 (42%), Gaps = 78/598 (13%) Query: 989 WILVGDDTAAV------LEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYV 1042 W ++G+D + L+ LTA R +I A G+ A + +V AAS G Sbjct: 4570 WAVLGEDEPDLRVGGERLDVYSGLTA--LREEIAA--GTSAPDVVVVPLSSAASGGGRAG 4625 Query: 1043 VHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV 1102 AA A A +++ L + L L R A + + VTD T Sbjct: 4626 TARAAAHHALALVKEWLADERLDGARLVLLTRGA----------VAAVPDEHVTDL-THA 4674 Query: 1103 PEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRDGEDQIALRGDAVYA 1162 P +WG R+A E P + LAD GAD + L A + + E Q+ALR +A Sbjct: 4675 P----VWGLVRSAQSENPGRFV-LADTDGADASFGALAAALATD---EPQLALRSGEAHA 4726 Query: 1163 PRLVR--RT-----GEPSDTPLPVREDR--------TYLVTGGLGAIGLEVAGYLAS-HG 1206 RL R RT GE P R D T LVTG G +G A +LA+ HG Sbjct: 4727 FRLRRIARTASDPAGETGTGDGPTRADDAGRIAADGTVLVTGASGTLGGLFARHLATTHG 4786 Query: 1207 AGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAG 1266 A H++L SRR + DV D AD +A ++ + A+ P L Sbjct: 4787 ARHLLLLSRRGDRAPGAGELTRELTEAGVDVTWAACDAADRDALAAVLAAIPADRP-LTA 4845 Query: 1267 IVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWG 1326 +VH AG + + L +D V KV AW+L E LT+ +L FV SS+A +G Sbjct: 4846 VVHTAGVLDDGIIDSLTPERLDTVLRPKVDAAWNLHE-LTEGH-ELSAFVLFSSVAGCFG 4903 Query: 1327 GFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW-----AAGMADAESRARLEQRGVR 1381 GQ Y AAN FLD LA + RG+TA S+ +G W AG D R+ + GV Sbjct: 4904 AAGQGNYAAANTFLDALAQHRKARGLTASSLAWGLWETTDGMAGALDEADLTRMARSGVA 4963 Query: 1382 TLSPAEALA------GMADVVAGPVQ---GVVAKIDWSRFLP-----LYQQAGRRAFLSE 1427 L+P E LA + D V P++ G + LP L + RRA S Sbjct: 4964 ALAPDEGLALFDTSRTLDDAVLVPMRIELGALRAQAADGTLPPLLRGLVRTPARRAAGST 5023 Query: 1428 LESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEI 1486 + L E+L +R + +R VA V D++ Sbjct: 5024 ARA---------GTRPGTDPAGTLEERLAGLSAAERDRALMELVRTQVAAVLGYAGPDDV 5074 Query: 1487 RDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGE 1544 GF DLG DSL AV+LR R+ G +PVTL+ D+P + A Y L E LG G+ Sbjct: 5075 DAARGFLDLGFDSLTAVDLRNRLTASAGLRLPVTLIFDYPSPTALAAY-LAERLGQGD 5131 Score = 137 bits (345), Expect = 3e-29 Identities = 121/363 (33%), Positives = 170/363 (46%), Gaps = 22/363 (6%) Query: 3298 LITGGLGAIGLHTAAYLA-QLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHTYAA- 3354 LITG GA+G A +LA + G ++L RR D A + E+ E + T+AA Sbjct: 2985 LITGATGALGGLFARHLAAEHGVERLLLVGRRGADAPGAAELVAELAESGT--LATWAAC 3042 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXX 3414 DV D +A LLA I AE PL + H AGVLDD ++S+ PER L PK A + Sbjct: 3043 DVADRDALAALLADIPAE-HPLTAVVHTAGVLDDGVISSLTPERLSAVLRPKVDAAWNLH 3101 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWG- 3473 PGQ NYA AN+ LD L RRA GL AT +G W Sbjct: 3102 ELTRGLDLAAFVLFSSTSGLFGGPGQGNYAAANSFLDALAQHRRAHGLPATSTAWGLWSV 3161 Query: 3474 QGGMASS-EAATAN-ITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQ--RAAKVL 3529 GMA + +AA N + GL PL + L ++ +++ + + R Sbjct: 3162 ADGMAGALDAADVNRMRRAGLPPLTAADGLGLFDTAVSLDEASLALMRVDTEVLRTQAGA 3221 Query: 3530 GSARPPILDLV-------LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL 3582 G+ P + LV + +AG +SEL +L + ++ + + ++ +V L Sbjct: 3222 GTIAPLLRGLVRGVARRSVDVSAGAGGAESELRGRLAALTAAEQDRALLDLVRTQVAAVL 3281 Query: 3583 RLASPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV 3640 A P A S F +LG DSL A+ELRNRL++ + AT +FDYP LA YL Sbjct: 3282 GHAGPAAVESGRAFKELGFDSLTAVELRNRLNA--ATALRLPATLIFDYPDPTVLARYLR 3339 Query: 3641 GQL 3643 G+L Sbjct: 3340 GEL 3342 Score = 123 bits (308), Expect = 6e-25 Identities = 115/373 (30%), Positives = 166/373 (44%), Gaps = 29/373 (7%) Query: 3294 DRSYLITGGLGAIGLHTAAYLAQL-GAGDIVLTSRR-DPDESAQRAIDEITERHKCRIHT 3351 D + L+TG G +G A +LA GA ++L SRR D A E+TE + Sbjct: 4761 DGTVLVTGASGTLGGLFARHLATTHGARHLLLLSRRGDRAPGAGELTRELTEAG-VDVTW 4819 Query: 3352 YAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS 3411 A D D +A +LA I A+ P L + H AGVLDD ++ + PER T L PK A Sbjct: 4820 AACDAADRDALAAVLAAIPADRP-LTAVVHTAGVLDDGIIDSLTPERLDTVLRPKVDAAW 4878 Query: 3412 HXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGP 3471 + GQ NYA AN LD L R+A+GL A+ + +G Sbjct: 4879 NLHELTEGHELSAFVLFSSVAGCFGAAGQGNYAAANTFLDALAQHRKARGLTASSLAWGL 4938 Query: 3472 W----GQGGMASSEAATANITAQGLIPL--DPSAALHALAEVIANGSGQATVLKANWQRA 3525 W G G A EA + G+ L D AL + + + ++ RA Sbjct: 4939 WETTDGMAG-ALDEADLTRMARSGVAALAPDEGLALFDTSRTLDDAVLVPMRIELGALRA 4997 Query: 3526 AKVLGSARPPILDLVLPSAAGEATGDS-------------ELLKQLMEIPIPQRAGFVTE 3572 G+ PP+L ++ + A A G + L ++L + +R + E Sbjct: 4998 QAADGTL-PPLLRGLVRTPARRAAGSTARAGTRPGTDPAGTLEERLAGLSAAERDRALME 5056 Query: 3573 FLQREVQNFLRLASPP--AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYP 3630 ++ +V L A P A+ FLDLG DSL A++LRNRL + G + + T +FDYP Sbjct: 5057 LVRTQVAAVLGYAGPDDVDAARGFLDLGFDSLTAVDLRNRLTASAGLRLPV--TLIFDYP 5114 Query: 3631 TIGGLAEYLVGQL 3643 + LA YL +L Sbjct: 5115 SPTALAAYLAERL 5127 >tr|Q3S864|Q3S864_9ACTO Tax_Id=42238 SubName: Full=Nodular polyketide synthase;[Streptomyces neyagawaensis] Length = 4970 Score = 1645 bits (4259), Expect = 0.0 Identities = 1137/3105 (36%), Positives = 1561/3105 (50%), Gaps = 192/3105 (6%) Query: 2 VSAEHPIEPTPSFAIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDP 59 V A P + AI+G + R+PG + E+ W L+ +GR+ IS +P DR WD++ +D Sbjct: 1569 VPAHVPADADDPIAIVGMSCRYPGDVRTPEDLWRLVAEGRDVISALPADRGWDLDGLYDT 1628 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 DP PG + GF+ D FD FFG+S RE MDPQ R+L+ET+W A+E +GI P Sbjct: 1629 DPDRPGTTYSSEGGFLYDAGQFDPAFFGISPREALAMDPQQRLLLETSWEALERAGIDPA 1688 Query: 120 SLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVA 179 SL GVF G A Y G++ E+E ++ G S + +GRI+Y LGL+GPAV Sbjct: 1689 SLRGGQVGVFAGAAYQGYGGLSD---VPEEVEGHLIAGISTSILSGRIAYTLGLEGPAVT 1745 Query: 180 VDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFD 239 VDTACSSSLVA+H A QALR EC LALAGG V+ TP + FS LA DGRCK+F Sbjct: 1746 VDTACSSSLVAVHLAAQALRSGECSLALAGGVTVMGTPLSFTGFSRQRGLAADGRCKSFG 1805 Query: 240 AAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI 299 A ADG+ EG G+++++RL DA R+G R+ A++RGSA+NQDGAS GLT P+G+AQQRVI Sbjct: 1806 ADADGFGMAEGVGLLLLERLSDARRNGHRVLALVRGSAVNQDGASNGLTAPSGLAQQRVI 1865 Query: 300 ADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGH 359 AL AG+ PA+V +EAHGTGT LGDPIEAQA G R + PLL+GS K+NIGH Sbjct: 1866 RSALAGAGVPPAEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPADRPLLLGSLKSNIGH 1925 Query: 360 LEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIA 419 + + +E LP+ L+ E P+P++ W +E++ E+ PW R G PR A Sbjct: 1926 SQAAAGVAGIIKMVQAMRHELLPRTLHAEVPTPNVDWSVGAVELLTESRPWTRGGHPRRA 1985 Query: 420 GVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYS---VLP--LSARTPEALVRLAG 474 GVSSFG +GTNAHVI+EE P EP E P + +P LS RTPEAL A Sbjct: 1986 GVSSFGLSGTNAHVIIEE------PYDEEPGEAPEGNAPGTAVPWLLSGRTPEALREQAA 2039 Query: 475 EYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVR 534 L P+ R DV T TAR+ E RA +V R + + L ALA P +VR Sbjct: 2040 RLHTHLTDRPELRPHDVGLTLATARSAFEHRAVVVGADRATLLTGLAALAAGENDPAVVR 2099 Query: 535 GESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDA 594 G + +T ++F GQGSQ+ GMA L D+ PVFAE + +C A++ L+ L DV+ A Sbjct: 2100 GTAATPGRTVFVFPGQGSQWVGMAVGLLDSAPVFAERIAECERALSPYLDWSLTDVLRAA 2159 Query: 595 DELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFD 654 + PL QP LF++ + LA LW+S+G EP VVGHS G+ +AA VAG Sbjct: 2160 PD-----SPPLDRVDVVQPVLFSMMVSLAALWRSYGVEPSAVVGHSQGEIAAAVVAGALT 2214 Query: 655 VEDGARLIAERGRLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNG-ANTVLSG 712 +EDGAR++A R ++ +L G M V E ERL LSVAA NG A +SG Sbjct: 2215 LEDGARIVARRSQILTALVGRGTMLFVALPDEEVRERLAPWAGKLSVAAVNGPAAVTVSG 2274 Query: 713 PAKDLESAVATLVADGV-RCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDN 771 + LE L DGV R + A HS +D + + + R Sbjct: 2275 DPEALEEFGERLSEDGVMRWTIPGVTFAGHSPQVDEVRGELLDALAGVAPRRTDIAFYST 2334 Query: 772 RTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWP 831 TG + +T LD YW R+ R+PVEF ++V L + +E GP PVLT + Sbjct: 2335 VTGGVVDTTT-LDTEYWYRNLREPVEFHRTVAALIEDGHDTFVETGPHPVLTVWIERSLE 2393 Query: 832 DPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHR 890 T +V +L + A+AA + G D+ A F DAR ++LPTY F+ + Sbjct: 2394 AADVTGRVTGTLLTDDGGPDRFLTALAAPHVHGVPVDWSAVFAGADARPVELPTYAFQRQ 2453 Query: 891 QFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLR---- 946 ++W A T + G+ P T +E G + +A ++ D+ Sbjct: 2454 RYWLEPT-ATAAGTAAGAPGADRPGDTAFWDAVERGDLTAVATALNLPDEDDSVRTSLGG 2512 Query: 947 VLNKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADAL 1006 VL LA +RS RY + + W +V AA Sbjct: 2513 VLPALADWQRGRRSRTAIDGWRYRVTYKTLHPAPGTPALTGTWWVVVPADAATHPMVTGA 2572 Query: 1007 TAGGHRHQIVALP----GSDADEAQLVDTLRAASAGELYVVHIAA------GDGAAAPMR 1056 RH +A+P +D D A L L AA+A + V+ + A DG A P Sbjct: 2573 LRALERHGALAVPVEIGAADNDRAALAARLGAAAAPDGGVLSLLALAEQPYTDGTALPTG 2632 Query: 1057 DLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAA 1115 L L +A DA + +P+W VT V +D + P Q+ LWG G A Sbjct: 2633 LALTTT---------LLQALGDAGINAPLWSVTCGAVSVGRSDALTAPAQATLWGLGAVA 2683 Query: 1116 ALELPHIWGGLADL-SGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSD 1174 +E P W GL DL + D +A + + DGEDQ+A+R +Y RLVR Sbjct: 2684 GVEYPERWAGLVDLPADLDDRSGGRLAAVLAGLDGEDQVAIRPSGIYGRRLVRALPGDET 2743 Query: 1175 TPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYA 1234 P+ + D T L+TGG GA+G VA LA G H++LT RR P Sbjct: 2744 APVAWKPDGTVLITGGTGALGAHVARRLARSGTRHLLLTGRRGPDTPGAAELVAELADLG 2803 Query: 1235 CDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGK 1294 + RV D AD +A L+ + + P L +VHAAG + L L V K Sbjct: 2804 AEARVAACDAADRDALAALLAGIPDDRP-LRAVVHAAGVLDDGVLDTLTPERAAGVLRPK 2862 Query: 1295 VWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTA 1354 + A +L DL DL FV SS+A GG GQ +Y AANA+LD LA R G+ A Sbjct: 2863 MDAARNLDALTRDL--DLSAFVLFSSLAGTLGGTGQGSYAAANAYLDALAEHRRSLGLPA 2920 Query: 1355 VSVNFGPWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFL 1413 +V +G WA A +R +L + G+ + P A+ + V G + ++ W RF Sbjct: 2921 TAVAWGLWAGDSAANSAREQLVRNGIPPMDPELAVTALEQAVEQGENRLILCDFAWDRFA 2980 Query: 1414 PLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRN 1473 P Y A L EL E L +L VQ+R+ + +R Sbjct: 2981 PAYTALRPSAVLRELP-EARDILAAAGADGQDTGADSLAGRLAALSVQERQEELVRLIRT 3039 Query: 1474 AVAEVTRV-DADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAA 1532 VA V D ++ + F DLG DSL AV+LR R+ + G + VTLV DHP ++ Sbjct: 3040 EVAAVLGYPDPADVDPDRVFKDLGFDSLTAVDLRNRLSEVTGLRLSVTLVFDHPTVTALV 3099 Query: 1533 DYLLVEVLGLGEQTN----VRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGG 1587 D++ E+ G + V + + DD IAVV++SCR+PG PE W L++ G Sbjct: 3100 DHVRSELGGTAPVSTSAPVVPDSPAMPVVDDDAIAVVSMSCRYPGGVTTPEELWRLVSSG 3159 Query: 1588 VDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEP 1646 DAI E P R WD+DE YDPDP+ G+TY R P FFGISPREA+ I+P Sbjct: 3160 ADAITEFPTGRGWDLDELYDPDPEKIGRTYAREGGFLHDADHFDPAFFGISPREALSIDP 3219 Query: 1647 QQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNA 1706 QQRL+LE WE ERAG P+ L+GSR GVF G + +Y + E ++ E + G+A Sbjct: 3220 QQRLLLEISWEAFERAGIDPASLKGSRAGVFVGSSYRDYGSRVQ-EPTEETEGYLGIGSA 3278 Query: 1707 LNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVT 1766 + SGR+++ G EGPAV VDTACSS+LVAVH A QAL+SG+C LALAGGV V+ +P Sbjct: 3279 GSVASGRISYTFGLEGPAVTVDTACSSSLVAVHLAAQALRSGECTLALAGGVTVMSTPGA 3338 Query: 1767 VVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVN 1826 + SR R L+ GRCK F +ADG +EG G++VL+RLSDA R+G V A++ S+VN Sbjct: 3339 FIEFSRQRGLAADGRCKPFAEAADGTAWAEGAGLVVLERLSDARRNGHPVLALVRGSAVN 3398 Query: 1827 QDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXX 1886 QDGAS+GLT PNG +QQR+I LA AGL+ ADVD +EAHGTGT LGDPIE Q Sbjct: 3399 QDGASNGLTAPNGPSQQRVIRQALASAGLNSADVDAVEAHGTGTRLGDPIEAQALLATYG 3458 Query: 1887 XXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDAL 1946 PLL+GS+K+N+GH ++A+G AGL K+VL+++HGVLP++LH + P+P + W A Sbjct: 3459 QDRPADRPLLLGSLKSNMGHAQAAAGIAGLQKMVLAMRHGVLPRTLHVDAPTPFVDWSAG 3518 Query: 1947 PVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXG 2006 V ++ E PW NG RRAG+SSFG +GTNAH ++E P + Sbjct: 3519 AVSLLTEDTPWPDNGHPRRAGISSFGVSGTNAHTILEHVPDE----YAPDGLDEAGDDAA 3574 Query: 2007 TDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVD 2066 D + LSARS AL A+R + A PGL AD+ HT GRS FEYR A+V D Sbjct: 3575 DDGTVLPWLLSARSRAALRAQAQRLLEHTDARPGLRPADIAHTLATGRSAFEYRGAVVGD 3634 Query: 2067 SVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQT 2126 S + GV +G V A+LF GQGSQ M EL+ PVFA Sbjct: 3635 SREALTGGLKALATGGSAPGVTQGTAV-AGKVAFLFAGQGSQRAAMGAELYARYPVFADA 3693 Query: 2127 VRQCAEAVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEP 2185 + + +L RPL +V+FA + A LL T + QPALFAVE+ L RL + W + P Sbjct: 3694 FDEICAELDPLLDRPLREVVFAPAGSDAAALLDRTEYTQPALFAVEVALFRLVEHWGVVP 3753 Query: 2186 DVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFA-DAEHVEQVA 2244 D++LGHS+G AAA VAGVF+ D A L+A RGR+ +LPEGG MVA+ A +A+ +A Sbjct: 3754 DLLLGHSIGVLAAAHVAGVFTAPDAAALVAARGRLMQALPEGGAMVALTASEADATALLA 3813 Query: 2245 GEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDX 2303 RV+V A NGP + V+SG + + ++ E++ D G + L SHAFHS +D +LD Sbjct: 3814 PYDGRVAVAAVNGPASVVVSGDEDAVLDLAEQWRDRGGKARRLTVSHAFHSPHMDAMLDE 3873 Query: 2304 XXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCS 2363 P +PLV + TG + T + +YW RH R+ V+F + +R +AA G Sbjct: 3874 FRRVAESLDYRAPRIPLVSDVTGELATPEQLGSPEYWVRHVREAVRFHDGMRRLAAEGAV 3933 Query: 2364 VLMEIGPQPVLTGAAVQVWPE-----------HMAAPRAVASLRKGVADRRQIADALASA 2412 +E+GP LT + E AA V LRK + R + DALA Sbjct: 3934 TYLELGPDGSLTAMGRDCFAEADPIGSDDPVDPSAAGPLVPLLRKDRTETRALTDALAQL 3993 Query: 2413 YVGGHRPDFAAVHRQPRR--PVELPTYPFQRRRFWPKASSIAVDGGTAASG-------IL 2463 YV G D+ V R VELPTY FQR R+W +A+ A GG AA+G +L Sbjct: 3994 YVRGTAVDWPTVLEATGRGGQVELPTYAFQRERYWLEAT--AASGGMAAAGLLPADHPLL 4051 Query: 2464 GSGKDLASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLK 2519 G+ LA D ++TSRLSV++ PWLADH ++GT + P +A+ A VG +++ Sbjct: 4052 GAAVPLADTDGVLFTSRLSVRTHPWLADHGVFGTALFPATALLELAVRAGDQVGC-GQVE 4110 Query: 2520 DVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGS 2579 ++ P+++P + S +QLT+ D +H+RP W+ +A G + Sbjct: 4111 ELTLETPLVIPAQGSVALQLTVGAPDSTGARPLSVHTRPGDTDDMGWTCHARGLL----- 4165 Query: 2580 DPDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLW-LGDGEAVG 2638 P A E +D V + +R L+E FA+ +GP + G L+ +W LGD Sbjct: 4166 VPAADETEPADSVTWPPTGAQPVRIDGLYERFAEGGFGYGPAFQG-LREVWRLGD----- 4219 Query: 2639 DILVGAELAEQLGSEP----MHPVLMD-----LCTGVXXXXXXXXXXXEQGVNDLFLPLR 2689 D+ A L + +E +HP L+D L GV +G + +LP Sbjct: 4220 DVYAEASLPPEQQAEAAKFGLHPALLDSALHALIFGVL-----------EGTDQGWLPFS 4268 Query: 2690 YGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREAL 2749 + + L R R + ++ D G+ + IR + Sbjct: 4269 WNGIRLHASGARALRIR------LTPAGNNAVSVQATDTAGQPVVSIRSL---------V 4313 Query: 2750 LRGLGGDATRL--------LYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPID 2801 LR + D R LY + W + P +AD W + G + G I Sbjct: 4314 LRPVNPDQVRAARTAHHDDLYRVEWPTLSRPAAADS--DGWAVIGPEAPDWAAHG---IT 4368 Query: 2802 RN-TDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXIT-NLLSAV 2859 R+ T L E LS+ A AG GV +T + L+ V Sbjct: 4369 RSATGL----EALSREIAGEAG--GVAPPTVVLAHVPAAPAGLGQPDAVRHVTGHTLTLV 4422 Query: 2860 HAAQGPSVKLPGGLWIVTEHGVACES-GEPVDPVQAALWGFGRTTINEEPALHCRLVDCD 2918 L +VT GV + G D AA+WG R+ E P L D D Sbjct: 4423 QEWLADDTFADAKLVLVTRGGVPVSADGVAQDLAHAAVWGLVRSAQTENPGRFV-LADLD 4481 Query: 2919 GSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLL-----------PWARSGHLTLPRG 2967 +SE EP++A+R+G+ +RL W R G + + G Sbjct: 4482 DASE-----DALVAAVASGEPQLALREGRTHIARLTKVPVTEQPGTPDWGRPGTVLITGG 4536 Query: 2968 GDFVLAPTER-----GAIDNLRLTETDVPEPDEGYVQVRVEAAGL 3007 + + R + L LT P EG + VE A L Sbjct: 4537 TGAIGSVLARHLAAEHGVKRLLLTSRRGPAA-EGAADLVVELAAL 4580 Score = 1453 bits (3762), Expect = 0.0 Identities = 994/2521 (39%), Positives = 1314/2521 (52%), Gaps = 135/2521 (5%) Query: 15 AIIGYAARFPGAAS-AEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + R+PG A E+ W ++ G +AIS+ P DR WD +DPDP PG TR Sbjct: 37 AIVSMSCRYPGGADDPEQLWDMVSSGTDAISEWPADRGWDTAALYDPDPDRPGTSYTRHG 96 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ FDA FFGMS RE DPQ R+L+ET+W +E +GI P L + TGVFVG Sbjct: 97 GFLHRAGEFDAAFFGMSPREALATDPQQRLLLETSWETLERAGIDPAVLKGTATGVFVGA 156 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 T+ Y + D+ +++ + GT+ + ISY LGL+GPAV VDTACSSSLVA+H Sbjct: 157 MTNGYGDGSRDQ---SDVQGLLHTGTAGSV----ISYTLGLEGPAVTVDTACSSSLVALH 209 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A +ALR EC LALA G V+ P + FS LAPDGRCK F A ADG EG G Sbjct: 210 LAIRALRSGECSLALACGVTVMPHPDPFVAFSRQRALAPDGRCKAFAAGADGTSWSEGVG 269 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V++++RL DA R G R+ AV+RGSA+NQDGAS GLT PNG +QQRVI AL A L P D Sbjct: 270 VLLLERLSDARRHGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALADARLLPGD 329 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R + PLL+GS K+NIGH Sbjct: 330 VDAVEAHGTGTRLGDPIEAQALLATYGQDRPADRPLLLGSLKSNIGHTSAAAGVGGVIKM 389 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRN-GKPRIAGVSSFGFAGTNA 431 L +E LP+ L+ + PSP + W +E++ E PW + +PR A VS FG +GTNA Sbjct: 390 VQALRHEVLPRTLHVDAPSPQVDWSAGAVELLTEERPWAFDPDRPRRAAVSGFGVSGTNA 449 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLPL-----SARTPEALVRLAGEYRDWLRAHPQA 486 HVILEEAP + E E P + LPL SAR +AL RA Sbjct: 450 HVILEEAPE-----SAETPEAPETATPLPLVPWVLSARGEDALTD---------RARQLL 495 Query: 487 RLAD--------VSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESH 538 LAD V+ T R+ LE RA +V E L ALA A LVRG + Sbjct: 496 ALADADALIPGAVARALATGRSPLEHRAVVVAGDAEGFRTGLTALATGGEAANLVRGLAG 555 Query: 539 EAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELD 598 A +T ++F GQG+Q+ GMA EL DT PVFA + C A+A ++ L DV+ A +L+ Sbjct: 556 PAGRTVFVFPGQGTQWTGMALELLDTSPVFAARMADCERALAPHVDWSLTDVLSSATDLE 615 Query: 599 GDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDG 658 QP L+AV + LA LW+S G EPD V+GHS G+ +AA VAG +EDG Sbjct: 616 --------RVDVVQPVLWAVMVSLAALWRSAGVEPDAVLGHSQGEIAAAVVAGALSLEDG 667 Query: 659 ARLIAERGRLFGSLPAGGRMAAVFTAPER-AERLTDEYPSLSVAAYNG-ANTVLSGPAKD 716 A+++A R + ++ G MA+V PE A L LSVAA NG A TVLSG + Sbjct: 668 AKVVALRSQAITAIAGRGGMASVPLPPEELAGHLGPWGDRLSVAAANGPAATVLSGDTEA 727 Query: 717 LESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSA 776 ++ VA L A+ VR + +A HSA ++ I + +E Q + + Sbjct: 728 IDGIVAQLQAEDVRARRIPVDYASHSAHVEEIRERLLECLADIEPTTGQ-VPFFSTVDLN 786 Query: 777 LGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATT 836 S LD YW R+ RQ V F ++ RTL R +E PVLT + Sbjct: 787 WQDSGALDAEYWYRNLRQTVRFEEATRTLLAQGFRFFVESSAHPVLTVGISQTAEAEESD 846 Query: 837 PQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPD-ARKLDLPTYPFEHRQFWFS 895 + +LR + ++A A+ G P++ +DLPTYPF+ R++W Sbjct: 847 AVAVGTLRRDQGGLDRFLLSLAEAHTGGLAPEWDTLLAGHPGDTVDLPTYPFQRRRYWLE 906 Query: 896 DNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETV-DEQTLRVLNKLAAR 954 A DT E ++L AL V E L V+ A Sbjct: 907 RPSAHAEDTAATDPADAA--------FWESVGGQDLPALTTTLGVRPEDPLTVVLPALAD 958 Query: 955 HNQQRSTHVDPDA-RYEIRW----DXXXXXXXXXXXXXDWILVGDDTA---AVLEFADAL 1006 ++R D+ RY + W D + V D T A AL Sbjct: 959 WRRRRDERATVDSWRYRVDWRPLADAPAGRTAAAPNGTWLVAVTDGTEGDPAREAAVRAL 1018 Query: 1007 TAGGHRHQIVALPGSDADEAQLVDTLRAASAGELY-VVHIAAGDGAAAPMRDLLRVQHRT 1065 G V L + D A L L AS G ++ V+ + A D P L + Sbjct: 1019 REAGAVPVPVVLTEAHTDRATLTAHLSEASTGPVHGVLSLVALDERPHPSHPHLPLG--- 1075 Query: 1066 LGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWG 1124 L L +A DA + +P+W TR D V P Q +WG GR AALE P WG Sbjct: 1076 LALTLTLVQALGDAGVTAPLWCATRGAVTTGRDDAVTSPGQHMVWGLGRCAALEHPQRWG 1135 Query: 1125 GLADLSGADTEWPRLIAR---ITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVRE 1181 GL DL DT R AR I + RD EDQ+A+R Y RLVR P+D P R Sbjct: 1136 GLVDLP--DTLDERAAARLCGILAGRDDEDQVAVRPSGAYGRRLVR--ARPAD---PARA 1188 Query: 1182 DR-----TYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACD 1236 D T LVTGG G +G +A +LA GA H+VL RR Sbjct: 1189 DAWQPRGTVLVTGGTGGVGAHLARWLAKGGAEHLVLVGRRGADTPGAADLTAELTALGTR 1248 Query: 1237 VRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVW 1296 V V DVAD +A L+ + + PP+ ++HAAG PLS D E KV Sbjct: 1249 VTVAACDVADRDRLAELVAGLEQDGPPIRTVIHAAGTGLLVPLSDTDPDEFADTLYAKVA 1308 Query: 1297 GAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVS 1356 GA +L +A+ D R DLD FV SSI+ VWG AY AANA LD LA R R RG TA S Sbjct: 1309 GAENL-DAVFD-RDDLDTFVLFSSISGVWGSGDHGAYAAANAHLDALADRRRARGRTATS 1366 Query: 1357 VNFGPW----AAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSR 1411 V +G W AGMA +L RG+ ++P AL G+ V+ V V +DW R Sbjct: 1367 VVWGIWDPEGGAGMAANLVEEQLRGRGIPFMAPQVALTGLQQVLTDDETVVLVTAVDWDR 1426 Query: 1412 FLPLYQQAGRRAFLSEL-ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNY 1470 F P++ A + +L E L +++ P R L+T+ Sbjct: 1427 FAPVFTSARPSPLIGDLPEVRRALAEETAPAQDGDDTASSLRDRIADLPPADRDRLLTDL 1486 Query: 1471 LR-NAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLS 1529 +R +A A + AD I E F +LG DSL AVE+R R+ G +P+T++ D+ Sbjct: 1487 VRGHAAAVLGHGSADAIAPERAFRELGFDSLTAVEMRNRLNAATGLRLPLTVLFDYASAD 1546 Query: 1530 DAADYLLVEVLG--LGEQTNVRQASTVTARTDDPIAVVAVSCRFPG-APDPESFWELLAG 1586 A +L E+LG T + V A DDPIA+V +SCR+PG PE W L+A Sbjct: 1547 ALARHLREELLGPDTAAPTGPAVPAHVPADADDPIAIVGMSCRYPGDVRTPEDLWRLVAE 1606 Query: 1587 GVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIE 1645 G D I +P DR WD+D YD DPD PG TY+ P FFGISPREA+ ++ Sbjct: 1607 GRDVISALPADRGWDLDGLYDTDPDRPGTTYSSEGGFLYDAGQFDPAFFGISPREALAMD 1666 Query: 1646 PQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGN 1705 PQQRL+LET WE LERAG P+ LRG + GVF G A Y L ++ +++E H I G Sbjct: 1667 PQQRLLLETSWEALERAGIDPASLRGGQVGVFAGAAYQGYGGL--SDVPEEVEGHLIAGI 1724 Query: 1706 ALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPV 1765 + + +SGR+A+ LG EGPAV VDTACSS+LVAVH A QAL+SG+C LALAGGV V+ +P+ Sbjct: 1725 STSILSGRIAYTLGLEGPAVTVDTACSSSLVAVHLAAQALRSGECSLALAGGVTVMGTPL 1784 Query: 1766 TVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSV 1825 + SR R L+ GRCK+F A ADG+ +EG G+L+L+RLSDA R+G RV A++ S+V Sbjct: 1785 SFTGFSRQRGLAADGRCKSFGADADGFGMAEGVGLLLLERLSDARRNGHRVLALVRGSAV 1844 Query: 1826 NQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXX 1885 NQDGAS+GLT P+G AQQR+I + LA AG+ A+VD +EAHGTGT LGDPIE Q Sbjct: 1845 NQDGASNGLTAPSGLAQQRVIRSALAGAGVPPAEVDVVEAHGTGTRLGDPIEAQALLATY 1904 Query: 1886 XXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDA 1945 PLL+GS+K+NIGH+++A+G AG+IK+V +++H +LP++LH E P+P++ W Sbjct: 1905 GQDRPADRPLLLGSLKSNIGHSQAAAGVAGIIKMVQAMRHELLPRTLHAEVPTPNVDWSV 1964 Query: 1946 LPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXX 2005 V ++ E PW G RRAGVSSFG +GTNAHV++EE + Sbjct: 1965 GAVELLTESRPWTRGGHPRRAGVSSFGLSGTNAHVIIEEPYDE---------EPGEAPEG 2015 Query: 2006 GTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALV- 2064 + LS R+PEAL E A R L+ P L DV T RS FE+RA +V Sbjct: 2016 NAPGTAVPWLLSGRTPEALREQAARLHTHLTDRPELRPHDVGLTLATARSAFEHRAVVVG 2075 Query: 2065 VDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFA 2124 D PA VVRG T ++F GQGSQ+ GMA L D+ PVFA Sbjct: 2076 ADRATLLTGLAALAAGENDPA-VVRGTAATPGRTVFVFPGQGSQWVGMAVGLLDSAPVFA 2134 Query: 2125 QTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIE 2184 + + +C A++ L L DVL A + L QP LF++ + LA LW+S+ +E Sbjct: 2135 ERIAECERALSPYLDWSLTDVLRAA--PDSPPLDRVDVVQPVLFSMMVSLAALWRSYGVE 2192 Query: 2185 PDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAV-FADAEHVEQV 2243 P V+GHS G+ AAA VAG +L+DGAR++A R ++ +L G M+ V D E E++ Sbjct: 2193 PSAVVGHSQGEIAAAVVAGALTLEDGARIVARRSQILTALVGRGTMLFVALPDEEVRERL 2252 Query: 2244 AGEFPRVSVGAYNGPNTV-LSGPGEDLEEIVERFEDEGI-RCTWLATSHAFHSELLDPVL 2301 A ++SV A NGP V +SG E LEE ER ++G+ R T + A HS +D V Sbjct: 2253 APWAGKLSVAAVNGPAAVTVSGDPEALEEFGERLSEDGVMRWTIPGVTFAGHSPQVDEVR 2312 Query: 2302 DXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALG 2361 + TG V+ T LD +YW R+ R+PV+F +V + G Sbjct: 2313 GELLDALAGVAPRRTDIAFYSTVTGGVV-DTTTLDTEYWYRNLREPVEFHRTVAALIEDG 2371 Query: 2362 CSVLMEIGPQPVLTGAAVQVWPEHM-----AAPRAVASLRKGVADRRQIADALASAYVGG 2416 +E GP PVLT VW E R +L + ALA+ +V G Sbjct: 2372 HDTFVETGPHPVLT-----VWIERSLEAADVTGRVTGTLLTDDGGPDRFLTALAAPHVHG 2426 Query: 2417 HRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSIAVDGGTAASGILGSGKDLASGDTI 2475 D++AV RPVELPTY FQR+R+W + ++ A GTAA G G+ + GDT Sbjct: 2427 VPVDWSAVFAGADARPVELPTYAFQRQRYWLEPTATA--AGTAA-GAPGADR---PGDTA 2480 Query: 2476 Y 2476 + Sbjct: 2481 F 2481 Score = 622 bits (1603), Expect = e-175 Identities = 407/976 (41%), Positives = 533/976 (54%), Gaps = 90/976 (9%) Query: 1560 DPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYT 1617 +PIA+V++SCR+P GA DPE W++++ G DAI E P DR WD YDPDPD PG +YT Sbjct: 34 EPIAIVSMSCRYPGGADDPEQLWDMVSSGTDAISEWPADRGWDTAALYDPDPDRPGTSYT 93 Query: 1618 RXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVF 1677 R FFG+SPREA+ +PQQRL+LET WE LERAG P+ L+G+ TGVF Sbjct: 94 RHGGFLHRAGEFDAAFFGMSPREALATDPQQRLLLETSWETLERAGIDPAVLKGTATGVF 153 Query: 1678 TGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVA 1737 G N Y + ++ TG A + IS + LG EGPAV VDTACSS+LVA Sbjct: 154 VGAMTNGYGD--GSRDQSDVQGLLHTGTAGSVIS----YTLGLEGPAVTVDTACSSSLVA 207 Query: 1738 VHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEG 1797 +H A +AL+SG+C LALA GV V+ P VA SR R L+P GRCK F A ADG SEG Sbjct: 208 LHLAIRALRSGECSLALACGVTVMPHPDPFVAFSRQRALAPDGRCKAFAAGADGTSWSEG 267 Query: 1798 CGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSG 1857 GVL+L+RLSDA R G RV AV+ S+VNQDGAS+GLT PNG +QQR+I A LA A L Sbjct: 268 VGVLLLERLSDARRHGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALADARLLP 327 Query: 1858 ADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLI 1917 DVD +EAHGTGT LGDPIE Q PLL+GS+K+NIGHT +A+G G+I Sbjct: 328 GDVDAVEAHGTGTRLGDPIEAQALLATYGQDRPADRPLLLGSLKSNIGHTSAAAGVGGVI 387 Query: 1918 KVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTN-GRVRRAGVSSFGFTGT 1976 K+V +L+H VLP++LH + PSP + W A V ++ E PW + R RRA VS FG +GT Sbjct: 388 KMVQALRHEVLPRTLHVDAPSPQVDWSAGAVELLTEERPWAFDPDRPRRAAVSGFGVSGT 447 Query: 1977 NAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL--------ALSARSPEALVELA 2028 NAHV++EEAP T ++P+ LSAR +AL + A Sbjct: 448 NAHVILEEAPESAE----------------TPEAPETATPLPLVPWVLSARGEDALTDRA 491 Query: 2029 RRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVV 2088 R+ L+ L V GRS E+RA +V A +V Sbjct: 492 RQLLA-LADADALIPGAVARALATGRSPLEHRAVVVAGDAEGFRTGLTALATGGEAANLV 550 Query: 2089 RGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVL-F 2147 RG T ++F GQG+Q+ GMA EL DT PVFA + C A+A + L DVL Sbjct: 551 RGLAGPAGRTVFVFPGQGTQWTGMALELLDTSPVFAARMADCERALAPHVDWSLTDVLSS 610 Query: 2148 ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSL 2207 ATD E D++ QP L+AV + LA LW+S +EPD VLGHS G+ AAA VAG SL Sbjct: 611 ATDLERVDVV------QPVLWAVMVSLAALWRSAGVEPDAVLGHSQGEIAAAVVAGALSL 664 Query: 2208 DDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF-PRVSVGAYNGP-NTVLSGP 2265 +DGA+++A R + ++ G M +V E + G + R+SV A NGP TVLSG Sbjct: 665 EDGAKVVALRSQAITAIAGRGGMASVPLPPEELAGHLGPWGDRLSVAAANGPAATVLSGD 724 Query: 2266 GEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRT 2325 E ++ IV + + E +R + +A HS ++ + + L C Sbjct: 725 TEAIDGIVAQLQAEDVRARRIPVDYASHSAHVEEIRERL---------------LECLAD 769 Query: 2326 GAVLTGQTP--------------LDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQ 2371 TGQ P LDA+YW R+ RQ V+F E+ RT+ A G +E Sbjct: 770 IEPTTGQVPFFSTVDLNWQDSGALDAEYWYRNLRQTVRFEEATRTLLAQGFRFFVESSAH 829 Query: 2372 PVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF-AAVHRQPRR 2430 PVLT Q + AV +LR+ + +LA A+ GG P++ + P Sbjct: 830 PVLTVGISQTAEAEESDAVAVGTLRRDQGGLDRFLLSLAEAHTGGLAPEWDTLLAGHPGD 889 Query: 2431 PVELPTYPFQRRRFW---PKA---SSIAVDGGTAASGILGSGKDLASGDTIYTSRLSVKS 2484 V+LPTYPFQRRR+W P A + A D AA G+DL + T+ L V+ Sbjct: 890 TVDLPTYPFQRRRYWLERPSAHAEDTAATDPADAAFWESVGGQDLPA----LTTTLGVRP 945 Query: 2485 QPWLADHVIYGTVVVP 2500 + L TVV+P Sbjct: 946 EDPL-------TVVLP 954 Score = 169 bits (427), Expect = 1e-38 Identities = 158/477 (33%), Positives = 218/477 (45%), Gaps = 27/477 (5%) Query: 1076 ANDAELRSPIWLVTRDGQRVTDTDTVVPE--QSCLWGFGRAAALELPHIWGGLADLSGAD 1133 A+D + + LVTR G V+ D V + + +WG R+A E P + LADL A Sbjct: 4427 ADDTFADAKLVLVTRGGVPVS-ADGVAQDLAHAAVWGLVRSAQTENPGRFV-LADLDDAS 4484 Query: 1134 TEWPRLIARITSPRDGEDQIALRGDAVYAPRLVR-RTGEPSDTPLPVREDRTYLVTGGLG 1192 + L+A + S GE Q+ALR + RL + E TP R T L+TGG G Sbjct: 4485 ED--ALVAAVAS---GEPQLALREGRTHIARLTKVPVTEQPGTPDWGRPG-TVLITGGTG 4538 Query: 1193 AIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVA 1251 AIG +A +LA+ HG ++LTSRR P ++ D AD +A Sbjct: 4539 AIGSVLARHLAAEHGVKRLLLTSRRGPAAEGAADLVVELAALGAHAEIVACDAADRDALA 4598 Query: 1252 RLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTD 1311 RL+ + + L +VHAAG I + + +D V KV AW+L E + D Sbjct: 4599 RLLGALPED-QSLTAVVHAAGTIADGVVDAMTPVRLDTVLRPKVDAAWNLHELTEGM--D 4655 Query: 1312 LDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA------AG 1365 L FV SSIA V+GG GQ Y AAN+FLD LA R+RG+ A S+ +G WA G Sbjct: 4656 LSAFVVFSSIAGVFGGMGQGNYAAANSFLDALAHHRRQRGLPAASLAWGLWANKGGMSGG 4715 Query: 1366 MADAESRARLEQRGVRTLSPAE--ALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRA 1423 + +A+ R R+ + G+ SPAE AL A+ + PV + ++D + G A Sbjct: 4716 LDEADFR-RIARGGIIAFSPAEGAALFDTANASSEPVV-LPLRLDTTALAAQSGADGVPA 4773 Query: 1424 FLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDA 1483 L L L L P +R + + +R A V Sbjct: 4774 LLRGLVRP-AARRSAAAGEAAPDAADTLRRTLAGQPEHRRLRTLLDLVRGHAAIVLGFPG 4832 Query: 1484 DEIRD-EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEV 1539 D E G +LG DSL AVELR R+ G +P TL+ DHP A L VE+ Sbjct: 4833 PASVDAERGLLELGFDSLTAVELRNRLGAATGLRLPATLLFDHPTSGAVARQLAVEL 4889 Score = 161 bits (408), Expect = 2e-36 Identities = 119/371 (32%), Positives = 169/371 (45%), Gaps = 36/371 (9%) Query: 3294 DRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYA 3353 D + LITGG GA+G H A LA+ G ++LT RR PD A + + E Sbjct: 2751 DGTVLITGGTGALGAHVARRLARSGTRHLLLTGRRGPDTPG--AAELVAE---------L 2799 Query: 3354 ADVGDEAQVA-------DLLARIRAELP---PLAGIAHLAGVLDDALLSAQNPERFRTTL 3403 AD+G EA+VA D LA + A +P PL + H AGVLDD +L PER L Sbjct: 2800 ADLGAEARVAACDAADRDALAALLAGIPDDRPLRAVVHAAGVLDDGVLDTLTPERAAGVL 2859 Query: 3404 APKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLV 3463 PK A + GQ +YA ANA LD L RR+ GL Sbjct: 2860 RPKMDAARNLDALTRDLDLSAFVLFSSLAGTLGGTGQGSYAAANAYLDALAEHRRSLGLP 2919 Query: 3464 ATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQ 3523 AT + +G W G +++ +A + G+ P+DP A+ AL + + G + + W Sbjct: 2920 ATAVAWGLW--AGDSAANSAREQLVRNGIPPMDPELAVTALEQAVEQGENRLILCDFAWD 2977 Query: 3524 RAAKVLGSARPPILDLVLPSAA---------GEATGDSELLKQLMEIPIPQRAGFVTEFL 3574 R A + RP + LP A G+ TG L +L + + +R + + Sbjct: 2978 RFAPAYTALRPSAVLRELPEARDILAAAGADGQDTGADSLAGRLAALSVQERQEELVRLI 3037 Query: 3575 QREVQNFLRLASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTI 3632 + EV L P F DLG DSL A++LRNRL G ++ T VFD+PT+ Sbjct: 3038 RTEVAAVLGYPDPADVDPDRVFKDLGFDSLTAVDLRNRLSEVTG--LRLSVTLVFDHPTV 3095 Query: 3633 GGLAEYLVGQL 3643 L +++ +L Sbjct: 3096 TALVDHVRSEL 3106 Score = 141 bits (356), Expect = 2e-30 Identities = 115/370 (31%), Positives = 167/370 (45%), Gaps = 21/370 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG G +G H A +LA+ GA +VL RR D + R+ A DV Sbjct: 1198 LVTGGTGGVGAHLARWLAKGGAEHLVLVGRRGADTPGAADLTAELTALGTRVTVAACDVA 1257 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D ++A+L+A + + PP+ + H AG LS +P+ F TL K GA + Sbjct: 1258 DRDRLAELVAGLEQDGPPIRTVIHAAGTGLLVPLSDTDPDEFADTLYAKVAGAENLDAVF 1317 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPW---GQ 3474 YA ANA LD L +RRA+G AT + +G W G Sbjct: 1318 DRDDLDTFVLFSSISGVWGSGDHGAYAAANAHLDALADRRRARGRTATSVVWGIWDPEGG 1377 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 GMA++ + +G+ + P AL L +V+ + V +W R A V SARP Sbjct: 1378 AGMAAN-LVEEQLRGRGIPFMAPQVALTGLQQVLTDDETVVLVTAVDWDRFAPVFTSARP 1436 Query: 3535 PILDLVLPS---AAGEAT-----GD---SELLKQLMEIPIPQRAGFVTEFLQREVQNFLR 3583 L LP A E T GD S L ++ ++P R +T+ ++ L Sbjct: 1437 SPLIGDLPEVRRALAEETAPAQDGDDTASSLRDRIADLPPADRDRLLTDLVRGHAAAVLG 1496 Query: 3584 LASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 S A + F +LG DSL A+E+RNRL++ G + + T +FDY + LA +L Sbjct: 1497 HGSADAIAPERAFRELGFDSLTAVEMRNRLNAATGLRLPL--TVLFDYASADALARHLRE 1554 Query: 3642 QL--PDAEAP 3649 +L PD AP Sbjct: 1555 ELLGPDTAAP 1564 Score = 126 bits (317), Expect = 6e-26 Identities = 123/366 (33%), Positives = 165/366 (45%), Gaps = 28/366 (7%) Query: 3298 LITGGLGAIGLHTAAYLA-QLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 LITGG GAIG A +LA + G ++LTSRR P +A+ A D + E H A V Sbjct: 4532 LITGGTGAIGSVLARHLAAEHGVKRLLLTSRRGP--AAEGAADLVVELAALGAH--AEIV 4587 Query: 3357 GDEAQVADLLARIRAELPP---LAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHX 3413 +A D LAR+ LP L + H AG + D ++ A P R T L PK A + Sbjct: 4588 ACDAADRDALARLLGALPEDQSLTAVVHAAGTIADGVVDAMTPVRLDTVLRPKVDAAWNL 4647 Query: 3414 XXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPW- 3472 GQ NYA AN+ LD L RR +GL A + +G W Sbjct: 4648 HELTEGMDLSAFVVFSSIAGVFGGMGQGNYAAANSFLDALAHHRRQRGLPAASLAWGLWA 4707 Query: 3473 GQGGMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLG 3530 +GGM+ EA I G+I P+ AL + AN S + VL A Sbjct: 4708 NKGGMSGGLDEADFRRIARGGIIAFSPAEGA-ALFDT-ANASSEPVVLPLRLDTTALAAQ 4765 Query: 3531 SAR---PPIL-DLVLP-----SAAGEATGDS--ELLKQLMEIPIPQRAGFVTEFLQREVQ 3579 S P +L LV P +AAGEA D+ L + L P +R + + ++ Sbjct: 4766 SGADGVPALLRGLVRPAARRSAAAGEAAPDAADTLRRTLAGQPEHRRLRTLLDLVRGHAA 4825 Query: 3580 NFLRLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAE 3637 L P + A L+LG DSL A+ELRNRL + G + AT +FD+PT G +A Sbjct: 4826 IVLGFPGPASVDAERGLLELGFDSLTAVELRNRLGAATG--LRLPATLLFDHPTSGAVAR 4883 Query: 3638 YLVGQL 3643 L +L Sbjct: 4884 QLAVEL 4889 >tr|D1SGG4|D1SGG4_9ACTO Tax_Id=644283 SubName: Full=Short-chain dehydrogenase/reductase SDR; Flags: Fragment;[Micromonospora aurantiaca ATCC 27029] Length = 5679 Score = 1645 bits (4259), Expect = 0.0 Identities = 1086/2718 (39%), Positives = 1446/2718 (53%), Gaps = 129/2718 (4%) Query: 15 AIIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + R+PG AS E+ W L+ G +AI P DR WD++ +DPD G+ TR Sbjct: 38 AIVAMSCRYPGGVASPEQLWDLVAAGGDAIGGFPTDRGWDLDNLYDPDADRAGRSTTREG 97 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE MDPQ R+L+ET+W A EH+GIAP S+ GVFVG Sbjct: 98 GFLYDAADFDAEFFGISPREAVAMDPQQRLLLETSWEAFEHAGIAPASMRGQKVGVFVGT 157 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 A + Y GM E Y+ GT+ + +GRI+Y LGL+GPAV VDTACSSSLVA+H Sbjct: 158 AANGY-GMGPQSEAEGADEGYLLTGTATSVVSGRIAYALGLEGPAVTVDTACSSSLVALH 216 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 ACQALR + DLALAGG V+ TP + FS LAPDGRCK+F AAADG EG G Sbjct: 217 LACQALRQGDFDLALAGGVCVMATPGPFVGFSRQRGLAPDGRCKSFAAAADGTGWSEGVG 276 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DA R G I AVIRGSA+NQDGAS GLT PNG AQQRVI AL A L AD Sbjct: 277 ILLVERLSDAQRKGHPILAVIRGSAVNQDGASNGLTAPNGPAQQRVIRQALANARLTTAD 336 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R + PLL+GS K+NIGH + Sbjct: 337 VDAVEAHGTGTVLGDPIEAQALLATYGRDRPADRPLLLGSIKSNIGHSQSAAGVAGVIKM 396 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + +P L+ + P+P + W + +V E PW +PR A VSSFG +GTNAH Sbjct: 397 VMAMRHGLVPSTLHVDEPTPKVDWSAGEVSLVTEATPWPATDRPRRAAVSSFGISGTNAH 456 Query: 433 VILEEAPAVGTPATTEPVE-DPRRYSVLP-----LSARTPEALVRLAGEYRDWLRAHPQA 486 I+EE P TP EP + P LP LSAR+ AL AG + WL Sbjct: 457 TIIEEPP---TPDAVEPADAGPAPTVALPAVPVLLSARSEAALGAQAGRWTRWLEDDEAL 513 Query: 487 RLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWL 546 R DV ++ +R+ LE RA L RE + L ALA +P+ LV G++ + A L Sbjct: 514 RTVDVGWSSVVSRSALEHRAVLTATDREELLAGLRALAAGQPSGALVAGQAADRGPLAVL 573 Query: 547 FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLR 606 F+GQG+Q GM REL+ PVFA + + + + +L +PL +V+F A E + E L Sbjct: 574 FSGQGAQRAGMGRELYAEFPVFAAALDEVSAQLDALLPRPLKEVLF-APEGSAEAEL-LD 631 Query: 607 HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERG 666 T + Q LFAVE+ L RL +S+G PD+V GHS+G+ +AA VAGV + D L+A RG Sbjct: 632 RTVFTQAGLFAVEVALFRLVESFGVAPDLVGGHSIGEVTAAHVAGVLSLADACVLVAARG 691 Query: 667 RLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLV 725 RL +LPAGG M AV A D + VAA NG + V+SG + L+ Sbjct: 692 RLMQALPAGGGMLAVAAAEADVLATLDGSTGVGVAAVNGPTSVVVSGAVEALDEVERVWR 751 Query: 726 ADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDG 785 GVR L SHAFHS L++P+LD+F L + P ++ N TG+ Sbjct: 752 GRGVRTRRLSVSHAFHSPLMEPMLDEFRVVLDGLTFEAPGLPVVSNVTGALADVDEIRSP 811 Query: 786 AYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATA--LAAWPDPAT----TPQV 839 YW RH R+ V FA V L LEIGPR VLTA A + + +PA TP V Sbjct: 812 DYWVRHVREAVRFADGVAALRAAGVDTFLEIGPRSVLTAMARDVLSGREPADVDDDTPVV 871 Query: 840 -LASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDN 897 + +LR + R + A++ + G D+ A + A + LPTY F+ +++W Sbjct: 872 AVPALRADRPESRALLAALSELHVNGTPVDWAALYAGTGATPVALPTYAFQRQRYW---- 927 Query: 898 RAIDRDTQTASAGSVTPHRTQAV--RLLEDGQIEELAALI--DGETVDEQTLRVLNKLAA 953 ++ G V+P +E + LAA I DG +D + + Sbjct: 928 ---PEQMPASATGPVSPDVVDVEFWSAVERSDVAALAAQIGVDGAALDVLAPALPVLSSW 984 Query: 954 RHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGD-DTAAVLEFADALT----- 1007 R + R VD + Y + W W+LV D AA E+A AL Sbjct: 985 RRARLRDAVVDGWS-YRVVWKRTAAPAPVTPSGR-WLLVEPADDAATTEWAGALAGALSA 1042 Query: 1008 AGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHR--- 1064 AGG ++ P ++ D+ T R A A V A G + + LL H Sbjct: 1043 AGGEVSRLAVDPLAERDQV----TSRVAQA-----VQNAPFTGIVS-LLGLLERPHPGRP 1092 Query: 1065 --TLG--GLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVP-EQSCLWGFGRAAALEL 1119 LG L +A + A++ +P+W++TR DTD V Q LWG R A LE Sbjct: 1093 AVPLGTAATMTLVQALHAADVTAPLWMLTRGAVGTGDTDPVRSVAQGGLWGLARVAGLEH 1152 Query: 1120 PHIWGGLADLSGADT--EWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPL 1177 P +WGGL DL A +W + +T EDQ+A+R V+ RLVR T Sbjct: 1153 PQLWGGLVDLPDAPGRGDWDHAVGVLTGGGP-EDQVAVRPSGVFVRRLVRATPAAVGAVD 1211 Query: 1178 PVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDV 1237 + T LVTGG GA+G VA + A++GA H+VLTSRR V Sbjct: 1212 RWQPSGTVLVTGGTGALGAHVARWAAANGAEHLVLTSRRGEHAPGAAELRDELTGLGARV 1271 Query: 1238 RVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWG 1297 ++ AD+AD V L+ V A+ PL +VHAAG T L D A + V GK+ G Sbjct: 1272 TLVAADMADRARVEALLRDVDADPAPLTAVVHAAGVGQLTMLVDTDLAGLAGVLDGKIAG 1331 Query: 1298 AWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSV 1357 A HL E L D LD FV SSIA +WG GQ AY A NAFLD LA R R RG+ A +V Sbjct: 1332 AVHLDELLGD--RPLDAFVLFSSIAGIWGSGGQAAYAAGNAFLDALAERRRARGLAATAV 1389 Query: 1358 NFGPWA-AGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPL 1415 +GPWA GMA E + L +RG+ +SPA+A+ + V V V VA +DWS F P Sbjct: 1390 AWGPWAEGGMASGEGQELLARRGLSPMSPAQAVYALRSAVGRAVPSVTVADVDWSLFTPA 1449 Query: 1416 YQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAV 1475 + A R L ++ +E L + L P ++ +T+ +R Sbjct: 1450 FAAARARPLLDDV-AEARDALRVVDAEPEDTAGGGLRQHLLTLPRAEQDRHLTDLVRTHT 1508 Query: 1476 AEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADY 1534 A V D ++ F +LG DSL AVELR R+ G +P TLV D+P + AD+ Sbjct: 1509 AAVLGHSGTDLVKAGRAFKELGFDSLTAVELRNRLGAATGLTLPTTLVFDYPNPAALADH 1568 Query: 1535 LLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIRE 1593 L V L L E V DPI +V +SCR+PG +P+ W+L+A G D I Sbjct: 1569 LSV-TLRLHEVETVTAWGPAGPVDGDPIVIVGMSCRYPGGVANPDDLWDLVATGRDGISG 1627 Query: 1594 VPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLML 1652 P+DR WD+ D D ++TR P FFGISPREAV ++PQQRL+L Sbjct: 1628 FPDDRHWDMGRLLAVDADGQPVSHTREGGFVDGATTFDPGFFGISPREAVAMDPQQRLLL 1687 Query: 1653 ETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISG 1712 E WE +E+AG P +LRG+RTGVF G + + Y + ++ ++ + +TG A + ISG Sbjct: 1688 EASWEAMEQAGIDPDELRGTRTGVFVGASPSGYG---TTDTPAELAGYQLTGGAHSVISG 1744 Query: 1713 RVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASR 1772 RV++ G EGPAV VDTACSS+LVAVH A QAL+ G+CD+ALAGGV V+++P V SR Sbjct: 1745 RVSYTFGLEGPAVTVDTACSSSLVAVHLAAQALRGGECDMALAGGVTVMVTPGAFVEFSR 1804 Query: 1773 ARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASS 1832 L+P GRCK+F A ADG SEG GVL+++RLSDA R G +V AV+ S+VNQDGAS+ Sbjct: 1805 QGGLAPDGRCKSFAADADGTGWSEGVGVLLVQRLSDARRQGRQVLAVLAGSAVNQDGASN 1864 Query: 1833 GLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXX 1892 GLT PNG AQQR+I LA A L+ ADVD +EAHGTGT LGDPIE Q Sbjct: 1865 GLTAPNGPAQQRVIRQALANARLTTADVDAVEAHGTGTTLGDPIEAQALLATYGQGRPAD 1924 Query: 1893 XPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVID 1952 PLL+GS+K+NIGH+++A+G AG+IK+V ++++G+LP++LH + P+PH+ W + V ++ Sbjct: 1925 RPLLLGSIKSNIGHSQAAAGVAGMIKMVQAMRYGLLPRTLHLDEPTPHVDWSSGAVSLLT 1984 Query: 1953 EPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEE--APPQLHXXXXXXXXXXXXXXXGTDDS 2010 E PW R RRA VSSFG +GTN H+++E+ AP T D Sbjct: 1985 EARPWPAVDRPRRAAVSSFGISGTNVHLILEQPSAPTDADEPADGDEPV-------TGDE 2037 Query: 2011 PQ------VLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALV 2064 P L LSAR L A R+ WL T DV ++ RS E+RA + Sbjct: 2038 PSRVPAVLPLLLSARDAAGLSAQAGRWAQWLGGTEAPRPLDVAWSSVASRSVLEHRAVVS 2097 Query: 2065 VDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFA 2124 S AGV+ G R A LF+GQG+Q GM REL+ PVFA Sbjct: 2098 GASRDELLAGLEAVSAGELSAGVLTGPGGQRGQLALLFSGQGAQRAGMGRELYGVFPVFA 2157 Query: 2125 QTVRQCAEAVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAI 2183 + + + +LPRPL +VLFA A+LL T F Q LFAVE+ L RL +S+ I Sbjct: 2158 AALDEVCGHLDPLLPRPLREVLFAEAGTSEAELLDQTVFTQAGLFAVEVALFRLVESFGI 2217 Query: 2184 EPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFAD-AEHVEQ 2242 PDVV GHS+G+ AA VAGV SL D L+A RGR+ +LP GG M+AV AD A E Sbjct: 2218 VPDVVAGHSIGEVTAAHVAGVLSLADACELVAARGRLMQALPTGGGMLAVAADEAAVAES 2277 Query: 2243 VAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVL 2301 VAG RV + A NGP V+SG E L E+ + D G+R L SHAFHS L+ P+L Sbjct: 2278 VAGLTDRVGIAAVNGPAAVVVSGAVEALAEVERAWRDRGVRTRRLTVSHAFHSPLMAPML 2337 Query: 2302 DXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALG 2361 D P LP+V N TGA L G +YW RH R+ V++A+ V + A G Sbjct: 2338 DEFRTVLGGLAFAAPLLPVVSNVTGA-LAGDEICTPEYWVRHVREAVRYADGVAALRAAG 2396 Query: 2362 CSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF 2421 +E+GPQ VLT + + A AVA R+ +D + + ALA +V G + Sbjct: 2397 VDTFLEVGPQSVLTAMNADLLADDEAV-LAVAVQRRDRSDAQALLHALAELHVHGVPVTW 2455 Query: 2422 AAVHRQP-RRPVELPTYPFQRRRFW--PKASSIAVDG---GTAASGILGSGKDLASGD-T 2474 + + R V+LPTY FQR R+W P S V G G A +LG+ +A D Sbjct: 2456 QSWFAETGARRVDLPTYAFQRERYWLPPAGQSADVSGAGLGVARHPLLGAAVSVAGEDMV 2515 Query: 2475 IYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPE 2531 + T RLSV + PWLADHV+ G VVVPG + + A VG +R++++ P++LP Sbjct: 2516 VLTGRLSVSTHPWLADHVVSGAVVVPGTALVDLVVRAGDEVGA-SRVRELTVLAPLVLPA 2574 Query: 2532 KASR-EVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVD-------TAGSDPDA 2583 VQ+ + P DG S +HS+ + + W+ +A+G VD T G+ P Sbjct: 2575 TGGGVRVQVRVGPVDGTGSRSVTVHSQSEDDPESGWTRHADGLVDAPTVDEPTLGAWPPP 2634 Query: 2584 AADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVG 2643 A E VD + T A+ LA+GP + G L+ W DGE ++ + Sbjct: 2635 GASE----VDVT----------GWYATVAEHGLAYGPVFRG-LRRAWTADGEVFAEVALA 2679 Query: 2644 AELAEQLGSEPMHPVLMD 2661 E A +HP L+D Sbjct: 2680 DEFAGDPAGFGVHPALLD 2697 Score = 957 bits (2473), Expect = 0.0 Identities = 723/2103 (34%), Positives = 1019/2103 (48%), Gaps = 148/2103 (7%) Query: 916 RTQAVRLLEDGQIEELAAL----IDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEI 971 RT VRL G L A + +VD TLR + LAA ++ + +E+ Sbjct: 2732 RTLRVRLTASGSSVRLVATDTTGVPVVSVDSLTLREMTGLAAAPDEAYRS------LFEV 2785 Query: 972 RWDXXXXXXXXXXXXXDWILVGD-------DTAAVLEFADALTAG--GHRHQIVALPGSD 1022 W W+++G A AD TA G + LP + Sbjct: 2786 SWQPEQIAAPDGTYG--WVVLGGRPLDGAPQLPAYAGVADLTTAATDGTAPAALLLPVTP 2843 Query: 1023 ADE-AQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAEL 1081 A A + D +R+ +A L VV AA P+ D RL A Sbjct: 2844 APSGADVPDAVRSVTADVLGVVQAWL---AAGPLAD------------SRLVVVTRGA-- 2886 Query: 1082 RSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIA 1141 + T RVTD + +WG R+A E P LADL L+A Sbjct: 2887 -----VATGADDRVTDL-----AGAAVWGLLRSAQSEHPGRIV-LADLEPGTDLDADLLA 2935 Query: 1142 RITSPRDGE---DQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEV 1198 + + DG Q+A+R Y PRLVR TG + TP + T LVTGG G++G V Sbjct: 2936 LLAAVADGPALGGQVAVRSGTAYLPRLVRATGA-ARTPEALGGG-TVLVTGGTGSLGALV 2993 Query: 1199 AGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTV 1257 + +L + +G +VL SR+ P RV+ DV D V L+ ++ Sbjct: 2994 SEHLVTAYGMRSLVLVSRQGPAAPGADELVRRLAALGATARVVATDVTDRERVGELVRSI 3053 Query: 1258 AAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVS 1317 A+ LAG+VH AG + +SG+ + V A KV W L EA +L DLD FV Sbjct: 3054 TAD-DRLAGVVHTAGVVDDGIVSGITADRLADVLAPKVTAGWWLHEATAEL--DLDLFVL 3110 Query: 1318 TSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW-----AAGMADAESR 1372 SS+A V G GQ AY A NAFLD LA +RG+ AVS+ +G W AA + DA+ R Sbjct: 3111 FSSVAGVLGSPGQAAYAAGNAFLDALAVLRAQRGLPAVSLAWGMWDTDGMAASINDAD-R 3169 Query: 1373 ARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESEL 1432 AR+ + G L P A G+ A G A + LP A R + + Sbjct: 3170 ARVTRAG---LVPMTAPVGLGLWDAALTHGGAALVPAVVDLP----AMRAQTAAGRVPVM 3222 Query: 1433 XXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAG 1491 ++L Q+ ++ + +R +A+V A+ + + Sbjct: 3223 LRGLVGPAAKRRRSGTGAWADRLAGLDPQEARTQVALLVRGMIAQVLGHGGAEAVPADRA 3282 Query: 1492 FFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQA 1551 F +LG DSL AVELR RI G + TLV D+P +++L ++ G Q +Q Sbjct: 3283 FRELGFDSLTAVELRNRINSASGLRLTSTLVFDYPTPGALSEHLYEQLSG---QVAAQQQ 3339 Query: 1552 STVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDP 1609 + D+PIA+V ++CR+PG +P+ W+L+A G D I E P DR WD+D + PDP Sbjct: 3340 AVRATTVDEPIAIVGMACRYPGGVTNPQQLWDLVAAGADGIGEFPTDRGWDLDRLFHPDP 3399 Query: 1610 DTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDL 1669 D PG +YTR P+FFGISPREA+ ++PQQRL+LE WE E AG PS L Sbjct: 3400 DNPGTSYTRHGGFLYGAAEFDPDFFGISPREAIAMDPQQRLLLEASWETFESAGLDPSRL 3459 Query: 1670 RGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDT 1729 RGSRTGVF G+ ++YA + + + + + TG + + +SGRVA+ G EGPAV VDT Sbjct: 3460 RGSRTGVFAGLMYHDYASGVQ-DLPEGVGGYLGTGTSGSVLSGRVAYTFGLEGPAVTVDT 3518 Query: 1730 ACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASA 1789 ACSS+LVA+H A QAL+ G+CDLALAGGV V+ +P T + SR R LS GRCK+F ASA Sbjct: 3519 ACSSSLVALHLAVQALRGGECDLALAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASA 3578 Query: 1790 DGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEAT 1849 DG SEG GVL+++RLSDA R+G RV AV+ ++VNQDGAS+GLT PNG +QQR+I Sbjct: 3579 DGTGWSEGVGVLLVERLSDARRNGHRVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQA 3638 Query: 1850 LARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTES 1909 LA A L+ ADVD +EAHGTGT LGDPIE Q PL +GSVK+NIGHT++ Sbjct: 3639 LANARLTAADVDAVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSVKSNIGHTQA 3698 Query: 1910 ASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVS 1969 A+GAAG+IK++++++HGVLP +LH + PSPHI W A V ++ E W GR RRA +S Sbjct: 3699 AAGAAGIIKMIMAMRHGVLPSTLHVDEPSPHIEWSAGAVSLLTEARDWPAAGRPRRAAIS 3758 Query: 1970 SFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELAR 2029 SFG +GTNAHV++E+ + P + LSARS A+ A Sbjct: 3759 SFGVSGTNAHVIIEQPHAEAEPTRGEGAPTPT-----AGQMPSPVLLSARSEAAVAAQAE 3813 Query: 2030 RYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVR 2089 R+ W++ L DV ++ V R+ E+RA + A VV Sbjct: 3814 RWARWIAGDEELRPLDVGWSSTVSRAVMEHRAVVTATDRDELLAGLRALADGEPAATVVT 3873 Query: 2090 GEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFAT 2149 G R A LF+GQG+Q GM REL+ PVFA + + + +LPRPL VLFA+ Sbjct: 3874 GTGATRTQLAVLFSGQGAQRAGMGRELYAGFPVFATALDEVCAQLDPLLPRPLQGVLFAS 3933 Query: 2150 DRET-ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLD 2208 A+LL T F Q LFAVE+ L RL +S+ + PDVV GHS+G+ AA VAGV SL Sbjct: 3934 SGSAEAELLDQTVFTQAGLFAVEVALFRLVESFGVVPDVVAGHSIGEVTAAHVAGVLSLA 3993 Query: 2209 DGARLMAERGRMFGSLPEGGRMVAVFAD-AEHVEQVAGEFPRVSVGAYNGP-NTVLSGPG 2266 D +L+A RGR+ +LP GG M+AV AD A E +AG R+ + A NGP V+SG Sbjct: 3994 DACQLVAARGRLMQALPTGGGMLAVAADEAAVAESLAGMTDRLGIAAVNGPAAVVVSGAV 4053 Query: 2267 EDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTG 2326 E L+E+ + + G+R L SHAFHS L++P+LD P LP+V N TG Sbjct: 4054 EALDEVERVWRERGVRTRRLTVSHAFHSPLMEPMLDEFRAVLAGLTFRAPLLPVVSNLTG 4113 Query: 2327 AVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHM 2386 A+ Q A+YW RH R+ V++A+ + + A G +EIGPQ VLT + E Sbjct: 4114 ALADPQEITRAEYWVRHVREAVRYADGIAALRATGVDTFLEIGPQSVLTAMNADLLAEDS 4173 Query: 2387 AAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQP-RRPVELPTYPFQRRRFW 2445 AVA R+ + + ALA +V G + V+LPTY FQ +R+W Sbjct: 4174 L---AVAVQRRDRPAPQALLHALADLHVHGVPVTWTQWFADAGAARVDLPTYAFQHQRYW 4230 Query: 2446 -----PKASSIAVDG-GTAASGILGSGKDLASGD-TIYTSRLSVKSQPWLADHVIYGTVV 2498 +A+ ++ G G A +LG+ +A D + T R+SV + WLADHV+ G VV Sbjct: 4231 LGAGQARAADVSGAGLGVAGHPLLGAAVSVAGVDMVVLTGRVSVSTHVWLADHVVSGAVV 4290 Query: 2499 VPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIH 2555 VPGA +A+ A VG +R++++ P++LPE + VQ+ + AD V +H Sbjct: 4291 VPGAALVELAVRAGDEVGA-SRVRELTVAAPLVLPEAGAVRVQVRVGAADETGVRVVAVH 4349 Query: 2556 SRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLE 2615 S+ G+ ADW +AEG ++ A + + + EV + T A+ Sbjct: 4350 SQSEGDPEADWVRHAEGVLEPASAGEPSLGEWPPVGASEV-------DVAGWYPTLAEHG 4402 Query: 2616 LAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXX 2675 LA+GP + G L+ +W G E ++ + E+A + +HP L+D Sbjct: 4403 LAYGPVFRG-LRRVWTGGDEVFAEVALPDEVATEAARFGVHPALLDAA-----LHPIGLL 4456 Query: 2676 XXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGG 2735 +G +P + V + + AR R L L D G A+ Sbjct: 4457 PGTEGSGGPRVPFAFEGVQV-------YASGARVLRVRLSRTGSAVRLVACDESGAAVVS 4509 Query: 2736 IREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVP 2795 + A RE G A R ++ L W + D + W + G A Sbjct: 4510 VDSL----ALRELTGVTAAGAAARAMFELTWQAEEIAATGD--LSGWALVGSPATA---- 4559 Query: 2796 GCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNL 2855 DL G+V + A AG + P + + Sbjct: 4560 ---------DLPAYGDVEALVAAVDAGRTVAPRALLLP---IDGPERAVPDAVRAATSEV 4607 Query: 2856 LSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRL 2914 L+ V + L +VT V+ + + V D AA+WG R+ +E P L Sbjct: 4608 LATVRSWLAADALAESRLVVVTRGAVSVAADDRVSDLAGAAVWGLLRSAQSEHPG-RIVL 4666 Query: 2915 VDCDGSSEA--VDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFVL 2972 D DG +A + P ++AVR G++ RL+ + + P GD + Sbjct: 4667 ADVDGDVDAGLLGVLTTVADEPSTHGGQVAVRSGEVFVPRLVRAVAAASVETPVVGDGAV 4726 Query: 2973 APT 2975 T Sbjct: 4727 VVT 4729 Score = 707 bits (1825), Expect = 0.0 Identities = 421/944 (44%), Positives = 550/944 (58%), Gaps = 23/944 (2%) Query: 1528 LSDAADYLLVEVL--GLGEQTNVRQAST-VTARTDDPIAVVAVSCRFPGA-PDPESFWEL 1583 +S +AD + VE L L E +RQ + +TA +PIA+VA+SCR+PG PE W+L Sbjct: 1 MSTSADKV-VEALRASLKETGRLRQLNQQLTAAAREPIAIVAMSCRYPGGVASPEQLWDL 59 Query: 1584 LAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAV 1642 +A G DAI P DR WD+D YDPD D G++ TR EFFGISPREAV Sbjct: 60 VAAGGDAIGGFPTDRGWDLDNLYDPDADRAGRSTTREGGFLYDAADFDAEFFGISPREAV 119 Query: 1643 WIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFI 1702 ++PQQRL+LET WE E AG AP+ +RG + GVF G AAN Y +E+ E + + Sbjct: 120 AMDPQQRLLLETSWEAFEHAGIAPASMRGQKVGVFVGTAANGYGMGPQSEAEGADEGYLL 179 Query: 1703 TGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLL 1762 TG A + +SGR+A+ALG EGPAV VDTACSS+LVA+H ACQAL+ GD DLALAGGV V+ Sbjct: 180 TGTATSVVSGRIAYALGLEGPAVTVDTACSSSLVALHLACQALRQGDFDLALAGGVCVMA 239 Query: 1763 SPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPA 1822 +P V SR R L+P GRCK+F A+ADG SEG G+L+++RLSDA R G + AVI Sbjct: 240 TPGPFVGFSRQRGLAPDGRCKSFAAAADGTGWSEGVGILLVERLSDAQRKGHPILAVIRG 299 Query: 1823 SSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXX 1882 S+VNQDGAS+GLT PNG AQQR+I LA A L+ ADVD +EAHGTGT LGDPIE Q Sbjct: 300 SAVNQDGASNGLTAPNGPAQQRVIRQALANARLTTADVDAVEAHGTGTVLGDPIEAQALL 359 Query: 1883 XXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIP 1942 PLL+GS+K+NIGH++SA+G AG+IK+V++++HG++P +LH + P+P + Sbjct: 360 ATYGRDRPADRPLLLGSIKSNIGHSQSAAGVAGVIKMVMAMRHGLVPSTLHVDEPTPKVD 419 Query: 1943 WDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXX 2002 W A V ++ E PW R RRA VSSFG +GTNAH ++EE P Sbjct: 420 WSAGEVSLVTEATPWPATDRPRRAAVSSFGISGTNAHTIIEEPP------TPDAVEPADA 473 Query: 2003 XXXGTDDSPQV-LALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRA 2061 T P V + LSARS AL A R+ WL L DV ++ V RS E+RA Sbjct: 474 GPAPTVALPAVPVLLSARSEAALGAQAGRWTRWLEDDEALRTVDVGWSSVVSRSALEHRA 533 Query: 2062 ALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQP 2121 L +V G+ R A LF+GQG+Q GM REL+ P Sbjct: 534 VLTATDREELLAGLRALAAGQPSGALVAGQAADRGPLAVLFSGQGAQRAGMGRELYAEFP 593 Query: 2122 VFAQTVRQCAEAVADMLPRPLLDVLFATDRET-ADLLQHTSFAQPALFAVEMGLARLWQS 2180 VFA + + + + +LPRPL +VLFA + A+LL T F Q LFAVE+ L RL +S Sbjct: 594 VFAAALDEVSAQLDALLPRPLKEVLFAPEGSAEAELLDRTVFTQAGLFAVEVALFRLVES 653 Query: 2181 WAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHV 2240 + + PD+V GHS+G+ AA VAGV SL D L+A RGR+ +LP GG M+AV A V Sbjct: 654 FGVAPDLVGGHSIGEVTAAHVAGVLSLADACVLVAARGRLMQALPAGGGMLAVAAAEADV 713 Query: 2241 EQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDP 2299 V V A NGP + V+SG E L+E+ + G+R L+ SHAFHS L++P Sbjct: 714 LATLDGSTGVGVAAVNGPTSVVVSGAVEALDEVERVWRGRGVRTRRLSVSHAFHSPLMEP 773 Query: 2300 VLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAA 2359 +LD P LP+V N TGA+ YW RH R+ V+FA+ V + A Sbjct: 774 MLDEFRVVLDGLTFEAPGLPVVSNVTGALADVDEIRSPDYWVRHVREAVRFADGVAALRA 833 Query: 2360 LGCSVLMEIGPQPVLTGAAVQVWPEHMAAP-------RAVASLRKGVADRRQIADALASA 2412 G +EIGP+ VLT A V A AV +LR + R + AL+ Sbjct: 834 AGVDTFLEIGPRSVLTAMARDVLSGREPADVDDDTPVVAVPALRADRPESRALLAALSEL 893 Query: 2413 YVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSIAVDG 2455 +V G D+AA++ PV LPTY FQR+R+WP+ + G Sbjct: 894 HVNGTPVDWAALYAGTGATPVALPTYAFQRQRYWPEQMPASATG 937 Score = 672 bits (1733), Expect = 0.0 Identities = 493/1261 (39%), Positives = 638/1261 (50%), Gaps = 93/1261 (7%) Query: 916 RTQAVRLLEDGQIEELAALIDGE----TVDEQTLRVLNKLAARHNQQRSTHVDPDARYEI 971 R VRL G L A + +VD LR L + A R A +E+ Sbjct: 4482 RVLRVRLSRTGSAVRLVACDESGAAVVSVDSLALRELTGVTAAGAAAR-------AMFEL 4534 Query: 972 RWDXXXXXXXXXXXXXDWILVGDDTAAVLEF---ADALTAGGHRHQIVA----LPGSDAD 1024 W W LVG A L +AL A + VA L D Sbjct: 4535 TWQAEEIAATGDLSG--WALVGSPATADLPAYGDVEALVAAVDAGRTVAPRALLLPIDGP 4592 Query: 1025 EAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSP 1084 E + D +RAA++ L A +R L A DA S Sbjct: 4593 ERAVPDAVRAATSEVL------------ATVRSWL----------------AADALAESR 4624 Query: 1085 IWLVTRDGQRVTDTDTVVP-EQSCLWGFGRAAALELPHIWGGLADLSG-ADTEWPRLIAR 1142 + +VTR V D V + +WG R+A E P LAD+ G D ++ Sbjct: 4625 LVVVTRGAVSVAADDRVSDLAGAAVWGLLRSAQSEHPGRIV-LADVDGDVDAGLLGVLTT 4683 Query: 1143 ITS-PRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGY 1201 + P Q+A+R V+ PRLVR S PV D +VTGG GA+G VA + Sbjct: 4684 VADEPSTHGGQVAVRSGEVFVPRLVRAVAAAS-VETPVVGDGAVVVTGGTGALGALVAEH 4742 Query: 1202 LAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAE 1260 L S HG +VL SRR VRV+ DV D V L+ VAAE Sbjct: 4743 LVSAHGVRSLVLVSRRGAEAAGAGELSERLSALGASVRVVACDVTDRDQVFGLVAEVAAE 4802 Query: 1261 LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS 1320 LAG+VH AG + + + + + V A KV W L EA L LD FV SS Sbjct: 4803 -GRLAGVVHTAGVLDDGVIERVTEERLVGVLAPKVSAGWLLHEATASLA--LDLFVVFSS 4859 Query: 1321 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW-AAGMA---DAESRARLE 1376 +A V G GQ+AY A NAFLDGLA R+ G+ AVS+ +G W AGMA D RAR Sbjct: 4860 VAGVLGSPGQSAYAAGNAFLDGLAVYRRQLGLPAVSLAWGMWDTAGMAASIDEADRARSA 4919 Query: 1377 QRGVRTLSPAEALAGM----ADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESEL 1432 + G L+P A G+ A +VA V A ID +P + A + + L Sbjct: 4920 RAG---LTPMSAEIGLELFDAALVAEQPALVPAVID----VPAMRAA---LGAGPVPAVL 4969 Query: 1433 XXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAG 1491 QL + ++ I +R VA+V A+ + + Sbjct: 4970 RTLIGSTAARRRAARSGDWANQLAGLAPDEARAQIDVLVRGLVAQVLGHGGAEAVPADRA 5029 Query: 1492 FFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQA 1551 F +LG DSL AV+LR R+ G + TLV D+P + AD+L +V G Q RQ Sbjct: 5030 FRELGFDSLTAVDLRNRLNAATGLRLASTLVFDYPTPAVLADHLHEQVSG---QITARQT 5086 Query: 1552 STVTARTDDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDP 1609 + +TA TD+PIA+V ++CR+PG D P+ W LLAGG D I E P DR WD++ +DPDP Sbjct: 5087 AVLTAGTDEPIAIVGMACRYPGGVDSPDQLWALLAGGGDGISEFPTDRGWDLESLFDPDP 5146 Query: 1610 DTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDL 1669 + G +YTR P FFGISPREA+ ++PQQRL+LE WE E AG P L Sbjct: 5147 EHSGTSYTRHGGFLYGAAEFDPGFFGISPREALAMDPQQRLLLEASWESFESAGLDPQRL 5206 Query: 1670 RGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDT 1729 RGSRTGVF GV ++YA L D E TG + + +SGRVA+ G EGPAV VDT Sbjct: 5207 RGSRTGVFAGVMYHDYASRLMDLPPDA-EGFVGTGTSGSVLSGRVAYTFGLEGPAVTVDT 5265 Query: 1730 ACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASA 1789 ACSS+LVA+H A QAL+SG+CDLALAGGV V+ +P T + SR R LS GRCK+F ASA Sbjct: 5266 ACSSSLVALHLAAQALRSGECDLALAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASA 5325 Query: 1790 DGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEAT 1849 DG SEG GVL+++RLSDA R+G RV AV+ ++VNQDGAS+GLT PNG +QQR+I Sbjct: 5326 DGTGWSEGVGVLLVERLSDARRNGHRVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQA 5385 Query: 1850 LARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTES 1909 LA A LS ADVD +EAHGTGT LGDPIE Q PLL+GSVK+NIGHT++ Sbjct: 5386 LANARLSPADVDAVEAHGTGTTLGDPIEAQALLATYGQERPQDRPLLLGSVKSNIGHTQA 5445 Query: 1910 ASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVS 1969 A+G AG+IK+VL+++HG++P +LH + SPH+ W A V + EP PW R RRA VS Sbjct: 5446 AAGVAGVIKMVLAMRHGLVPATLHVDEASPHVDWSAGAVALATEPTPWPRVDRPRRAAVS 5505 Query: 1970 SFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV-LALSARSPEALVELA 2028 SFG +GTNAHV++E+ P + D P V + LSAR AL A Sbjct: 5506 SFGISGTNAHVIIEQPPAE----------TIEGEIVARDVPPVVPVLLSARDAAALSAQA 5555 Query: 2029 RRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVV 2088 R+ WL+A D+ ++ R E+RA + V Sbjct: 5556 GRWARWLTADEAPRPLDLAWSSVTTRPALEHRAVVTAADRDDLVAALTALADGDPTGTAV 5615 Query: 2089 RGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFA 2148 G R A LF+GQG+Q GM REL PVFA + + + +LPRPL +VLFA Sbjct: 5616 SGATGQRGRLALLFSGQGAQRAGMGRELSAGFPVFAAALDEVCGHLDPLLPRPLREVLFA 5675 Query: 2149 T 2149 + Sbjct: 5676 S 5676 Score = 641 bits (1653), Expect = 0.0 Identities = 378/907 (41%), Positives = 505/907 (55%), Gaps = 21/907 (2%) Query: 15 AIIGYAARFPGAAS-AEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G A R+PG + ++ W L+ G + I + P DR WD++ F PDP PG TR Sbjct: 3351 AIVGMACRYPGGVTNPQQLWDLVAAGADGIGEFPTDRGWDLDRLFHPDPDNPGTSYTRHG 3410 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ FD FFG+S RE MDPQ R+L+E +W E +G+ P+ L S TGVF GL Sbjct: 3411 GFLYGAAEFDPDFFGISPREAIAMDPQQRLLLEASWETFESAGLDPSRLRGSRTGVFAGL 3470 Query: 133 ATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 HDY D PE + Y+ GTS + +GR++Y GL+GPAV VDTACSSSLVA+ Sbjct: 3471 MYHDYASGVQD---LPEGVGGYLGTGTSGSVLSGRVAYTFGLEGPAVTVDTACSSSLVAL 3527 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR ECDLALAGG V+ TP T I FS L+ DGRCK+F A+ADG EG Sbjct: 3528 HLAVQALRGGECDLALAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASADGTGWSEGV 3587 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 GV++V+RL DA R+G R+ AV+RG+A+NQDGAS GLT PNG +QQRVI AL A L A Sbjct: 3588 GVLLVERLSDARRNGHRVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANARLTAA 3647 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT+LGDPIEAQA G R + PL +GS K+NIGH + Sbjct: 3648 DVDAVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSVKSNIGHTQAAAGAAGIIK 3707 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 + + LP L+ + PSPHI W + ++ E W G+PR A +SSFG +GTNA Sbjct: 3708 MIMAMRHGVLPSTLHVDEPSPHIEWSAGAVSLLTEARDWPAAGRPRRAAISSFGVSGTNA 3767 Query: 432 HVILEEAPAVGTPATTEPVEDP---RRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARL 488 HVI+E+ A P E P + S + LSAR+ A+ A + W+ + R Sbjct: 3768 HVIIEQPHAEAEPTRGEGAPTPTAGQMPSPVLLSARSEAAVAAQAERWARWIAGDEELRP 3827 Query: 489 ADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFT 548 DV ++ +RA +E RA + R+ + L ALAD PA +V G + A LF+ Sbjct: 3828 LDVGWSSTVSRAVMEHRAVVTATDRDELLAGLRALADGEPAATVVTGTGATRTQLAVLFS 3887 Query: 549 GQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESP-LRH 607 GQG+Q GM REL+ PVFA + + + +L +PL V+F + G E+ L Sbjct: 3888 GQGAQRAGMGRELYAGFPVFATALDEVCAQLDPLLPRPLQGVLFAS---SGSAEAELLDQ 3944 Query: 608 TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGR 667 T + Q LFAVE+ L RL +S+G PDVV GHS+G+ +AA VAGV + D +L+A RGR Sbjct: 3945 TVFTQAGLFAVEVALFRLVESFGVVPDVVAGHSIGEVTAAHVAGVLSLADACQLVAARGR 4004 Query: 668 LFGSLPAGGRMAAVFTAPER--AERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATL 724 L +LP GG M AV A E AE L L +AA NG A V+SG + L+ Sbjct: 4005 LMQALPTGGGMLAV-AADEAAVAESLAGMTDRLGIAAVNGPAAVVVSGAVEALDEVERVW 4063 Query: 725 VADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLD 784 GVR L SHAFHS L++P+LD+F + L +R P ++ N TG+ Sbjct: 4064 RERGVRTRRLTVSHAFHSPLMEPMLDEFRAVLAGLTFRAPLLPVVSNLTGALADPQEITR 4123 Query: 785 GAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLR 844 YW RH R+ V +A + L LEIGP+ VLTA + + V R Sbjct: 4124 AEYWVRHVREAVRYADGIAALRATGVDTFLEIGPQSVLTAMNADLLAEDSLAVAVQRRDR 4183 Query: 845 PTTADHRQITEAVAAAYAAG-HLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRD 903 P + + A+A + G + + F A ++DLPTY F+H+++W +A D Sbjct: 4184 PAP---QALLHALADLHVHGVPVTWTQWFADAGAARVDLPTYAFQHQRYWLGAGQARAAD 4240 Query: 904 TQTASAG 910 A G Sbjct: 4241 VSGAGLG 4247 Score = 489 bits (1259), Expect = e-135 Identities = 269/580 (46%), Positives = 346/580 (59%), Gaps = 5/580 (0%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G A R+PG S ++ WALL G + IS+ P DR WD+E FDPDP G TR Sbjct: 5098 AIVGMACRYPGGVDSPDQLWALLAGGGDGISEFPTDRGWDLESLFDPDPEHSGTSYTRHG 5157 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ FD FFG+S RE MDPQ R+L+E +W + E +G+ P L S TGVF G+ Sbjct: 5158 GFLYGAAEFDPGFFGISPREALAMDPQQRLLLEASWESFESAGLDPQRLRGSRTGVFAGV 5217 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 HDY D P+ E ++ GTS + +GR++Y GL+GPAV VDTACSSSLVA+H Sbjct: 5218 MYHDYASRLMD--LPPDAEGFVGTGTSGSVLSGRVAYTFGLEGPAVTVDTACSSSLVALH 5275 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR ECDLALAGG V+ TP T I FS L+ DGRCK+F A+ADG EG G Sbjct: 5276 LAAQALRSGECDLALAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASADGTGWSEGVG 5335 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V++V+RL DA R+G R+ AV+RG+A+NQDGAS GLT PNG +QQRVI AL A L PAD Sbjct: 5336 VLLVERLSDARRNGHRVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANARLSPAD 5395 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT+LGDPIEAQA G R + PLL+GS K+NIGH + Sbjct: 5396 VDAVEAHGTGTTLGDPIEAQALLATYGQERPQDRPLLLGSVKSNIGHTQAAAGVAGVIKM 5455 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + +P L+ + SPH+ W + + E PW R +PR A VSSFG +GTNAH Sbjct: 5456 VLAMRHGLVPATLHVDEASPHVDWSAGAVALATEPTPWPRVDRPRRAAVSSFGISGTNAH 5515 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVS 492 VI+E+ PA + P VL LSAR AL AG + WL A R D++ Sbjct: 5516 VIIEQPPAETIEGEIVARDVPPVVPVL-LSARDAAALSAQAGRWARWLTADEAPRPLDLA 5574 Query: 493 HTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQGS 552 ++ T R LE RA + R+ + L ALAD P V G + + + A LF+GQG+ Sbjct: 5575 WSSVTTRPALEHRAVVTAADRDDLVAALTALADGDPTGTAVSGATGQRGRLALLFSGQGA 5634 Query: 553 QYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIF 592 Q GM REL PVFA + + + +L +PL +V+F Sbjct: 5635 QRAGMGRELSAGFPVFAAALDEVCGHLDPLLPRPLREVLF 5674 Score = 162 bits (410), Expect = 9e-37 Identities = 119/354 (33%), Positives = 165/354 (46%), Gaps = 16/354 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRR-DPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TGG GA+G H A + A GA +VLTSRR + A DE+T R+ AAD+ Sbjct: 1220 LVTGGTGALGAHVARWAAANGAEHLVLTSRRGEHAPGAAELRDELTGLG-ARVTLVAADM 1278 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D A+V LL + A+ PL + H AGV +L + L K GA H Sbjct: 1279 ADRARVEALLRDVDADPAPLTAVVHAAGVGQLTMLVDTDLAGLAGVLDGKIAGAVHLDEL 1338 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQA YA NA LD L +RRA+GL AT + +GPW +GG Sbjct: 1339 LGDRPLDAFVLFSSIAGIWGSGGQAAYAAGNAFLDALAERRRARGLAATAVAWGPWAEGG 1398 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP-P 3535 MAS E + +GL P+ P+ A++AL + TV +W +AR P Sbjct: 1399 MASGEGQEL-LARRGLSPMSPAQAVYALRSAVGRAVPSVTVADVDWSLFTPAFAAARARP 1457 Query: 3536 ILD--------LVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 +LD L + A E T L + L+ +P ++ +T+ ++ L + Sbjct: 1458 LLDDVAEARDALRVVDAEPEDTAGGGLRQHLLTLPRAEQDRHLTDLVRTHTAAVLGHSGT 1517 Query: 3588 P--AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 A F +LG DSL A+ELRNRL + G T+ T VFDYP LA++L Sbjct: 1518 DLVKAGRAFKELGFDSLTAVELRNRLGAATG--LTLPTTLVFDYPNPAALADHL 1569 Score = 135 bits (340), Expect = 1e-28 Identities = 111/356 (31%), Positives = 156/356 (43%), Gaps = 16/356 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKC---RIHTYA 3353 L+TGG G++G + +L G +VL SR+ P A DE+ R A Sbjct: 2981 LVTGGTGSLGALVSEHLVTAYGMRSLVLVSRQGP---AAPGADELVRRLAALGATARVVA 3037 Query: 3354 ADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHX 3413 DV D +V +L+ I A+ LAG+ H AGV+DD ++S +R LAPK Sbjct: 3038 TDVTDRERVGELVRSITAD-DRLAGVVHTAGVVDDGIVSGITADRLADVLAPKVTAGWWL 3096 Query: 3414 XXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWG 3473 PGQA YA NA LD L R +GL A + +G W Sbjct: 3097 HEATAELDLDLFVLFSSVAGVLGSPGQAAYAAGNAFLDALAVLRAQRGLPAVSLAWGMWD 3156 Query: 3474 QGGMASS--EAATANITAQGLIPLDPSAALHALAEVIANGSGQ--ATVLKANWQRAAKVL 3529 GMA+S +A A +T GL+P+ L + +G V+ RA Sbjct: 3157 TDGMAASINDADRARVTRAGLVPMTAPVGLGLWDAALTHGGAALVPAVVDLPAMRAQTAA 3216 Query: 3530 GSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA 3589 G + LV P+A +G +L + + V ++ + L A Sbjct: 3217 GRVPVMLRGLVGPAAKRRRSGTGAWADRLAGLDPQEARTQVALLVRGMIAQVLGHGGAEA 3276 Query: 3590 --ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A F +LG DSL A+ELRNR++S G + T +T VFDYPT G L+E+L QL Sbjct: 3277 VPADRAFRELGFDSLTAVELRNRINSASGLRLT--STLVFDYPTPGALSEHLYEQL 3330 Score = 130 bits (328), Expect = 3e-27 Identities = 113/359 (31%), Positives = 154/359 (42%), Gaps = 13/359 (3%) Query: 3294 DRSYLITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTY 3352 D + ++TGG GA+G A +L G +VL SRR + + + E + Sbjct: 4723 DGAVVVTGGTGALGALVAEHLVSAHGVRSLVLVSRRGAEAAGAGELSERLSALGASVRVV 4782 Query: 3353 AADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASH 3412 A DV D QV L+A + AE LAG+ H AGVLDD ++ ER LAPK Sbjct: 4783 ACDVTDRDQVFGLVAEVAAE-GRLAGVVHTAGVLDDGVIERVTEERLVGVLAPKVSAGWL 4841 Query: 3413 XXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPW 3472 PGQ+ YA NA LDGL RR GL A + +G W Sbjct: 4842 LHEATASLALDLFVVFSSVAGVLGSPGQSAYAAGNAFLDGLAVYRRQLGLPAVSLAWGMW 4901 Query: 3473 GQGGMASS--EAATANITAQGLIPLDPSAALHAL--AEVIANGSGQATVLKANWQRAAKV 3528 GMA+S EA A GL P+ L A V + V+ RAA Sbjct: 4902 DTAGMAASIDEADRARSARAGLTPMSAEIGLELFDAALVAEQPALVPAVIDVPAMRAALG 4961 Query: 3529 LGSARPPILDLVLPSAAG--EATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 G P +L ++ S A A + QL + + + ++ V L Sbjct: 4962 AGPV-PAVLRTLIGSTAARRRAARSGDWANQLAGLAPDEARAQIDVLVRGLVAQVLGHGG 5020 Query: 3587 PPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A A F +LG DSL A++LRNRL++ G + +T VFDYPT LA++L Q+ Sbjct: 5021 AEAVPADRAFRELGFDSLTAVDLRNRLNAATG--LRLASTLVFDYPTPAVLADHLHEQV 5077 >tr|Q52V44|Q52V44_9ACTO Tax_Id=255848 SubName: Full=Polyketide synthase type I;[Streptomyces aizunensis] Length = 6751 Score = 1640 bits (4247), Expect = 0.0 Identities = 1082/2708 (39%), Positives = 1455/2708 (53%), Gaps = 158/2708 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + RFPG + E+ W LL G +AISD+P DR WDI+ +D DPST G R Sbjct: 3363 AIVSMSCRFPGGVRTPEDLWELLSTGGDAISDLPLDRGWDIDALYDADPSTQGTSYARAG 3422 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE MDPQ R+L+ET+W A E +GI P +L S GVFVG Sbjct: 3423 GFLYDAADFDADFFGISPREALAMDPQQRLLLETSWEAFERAGIDPETLRGSQAGVFVGT 3482 Query: 133 ATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 DYL + +E PE +E ++ G + + +GR+SY GL+GPAV VDTACSSSLVA+ Sbjct: 3483 NGQDYLSVLLEE---PEGLEGHLGTGNAASVVSGRLSYVFGLEGPAVTVDTACSSSLVAL 3539 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR EC LALAGG V+ TP T I FS LA DGR K F AAADG GEG Sbjct: 3540 HWAIQALRNGECSLALAGGVTVMSTPGTFIEFSRQRGLAEDGRIKAFAAAADGTGWGEGV 3599 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 G+++V+RL DA R+G + A++RGSAINQDGAS GLT PNG +QQRVI AL AGL A Sbjct: 3600 GMLLVERLSDAERNGHPVLAIVRGSAINQDGASNGLTAPNGPSQQRVIRAALASAGLSAA 3659 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT+LGDPIEAQA G R + PL +GS K+NIGH + Sbjct: 3660 DVDAVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLQLGSIKSNIGHTQAAAGVAGVIK 3719 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 +E+ LP+ L+ + PSP + WE I ++ E W G+PR AGVSSFGF+GTNA Sbjct: 3720 MVLAMEHGVLPQSLHIDAPSPQVDWEAGDIALLTEQRQWPETGRPRRAGVSSFGFSGTNA 3779 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADV 491 H I+E+APA E + L LSA++ AL A R L A P RL+DV Sbjct: 3780 HTIIEQAPASTETDRAESGSVEPDFVPLMLSAKSDVALRAQAASLRARLIAAPDMRLSDV 3839 Query: 492 SHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQG 551 T T R+ E+RAALV RE + L ALAD A GLV G S + K A+LFTGQG Sbjct: 3840 GSTLTTGRSAFERRAALVAGGREGLLAGLEALADGGSAAGLVEG-SPVSGKLAFLFTGQG 3898 Query: 552 SQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYA 611 SQ GM REL++ PVFA+ + +AV LE PL+DV+F AD L T Y Sbjct: 3899 SQRLGMGRELYEAYPVFADAL----DAVCVRLELPLMDVLFGADA------GLLNETAYT 3948 Query: 612 QPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGS 671 QPALFAVE+ L RL +SWG PD + GHS+G+ +AA VAGV ++D L+ RGRL G+ Sbjct: 3949 QPALFAVEVALFRLVESWGLRPDFLAGHSIGEIAAAHVAGVLSLDDACALVEARGRLMGA 4008 Query: 672 LPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVA-DGV 729 LPAGG M AV + + LTD +S+AA NG +V+ A D AVA + + G Sbjct: 4009 LPAGGVMIAVQASEDEVLPLLTDR---VSIAAINGPQSVVI--AGDEADAVAIVESFTGR 4063 Query: 730 RCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWR 789 + L SHAFHS +D +L+DF A+ L Y P+ ++ N TG AL +W Sbjct: 4064 KSKRLSVSHAFHSPHMDGMLEDFRVVAEGLSYDAPRIPVVSNLTG-ALVTDEMGSADFWV 4122 Query: 790 RHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTAD 849 RH R+ V F +R L +E+GP VL+A A + + LR + Sbjct: 4123 RHVREAVRFLDGIRALEAAGVTTYVELGPDGVLSAMAQECVTEGGAA--FVPVLRKGRPE 4180 Query: 850 HRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASA 909 + + A+ G D+ + A+++DLPTY F+ +++W +++A Sbjct: 4181 AETVMATLGQAHVRGVAVDWHSVYGTGAQRVDLPTYSFQRQRYW---------PAASSTA 4231 Query: 910 GSVTPHRTQAV--RLLEDGQIEELAALIDGETVDEQT--LRVLNKLAARHNQQRSTHVDP 965 G AV R + + E+LA+L +D+ + L+A ++R+ Sbjct: 4232 GGSVDRSVDAVDARFWDAVEREDLASLAAELDLDDDAPFSELAPALSAWRRERRALSEVD 4291 Query: 966 DARYEIRWDXXXXXXXXXXXXXDWILVG-----DDTAAVLEFADALTAGGHRHQIVALPG 1020 RY + W W+++ DD+A V + G ++V G Sbjct: 4292 GWRYRVSWKPLADVSASGLSG-SWVVISPAGGVDDSAVV---GALVGRGAEVRRVVVEAG 4347 Query: 1021 SDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRV-QHRTLGGLRRLFRAANDA 1079 D R+A AG L A G+AA + LL + + L G L +A DA Sbjct: 4348 VD----------RSALAGLL------ADAGSAAGVVSLLGLDESEGLLGTVGLVQALGDA 4391 Query: 1080 ELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLSGADTEWP- 1137 + +P+W +TR V +D +V P Q+ +WG GR AALE+P WGGL DL E Sbjct: 4392 GVEAPLWCLTRGAVSVGRSDRLVSPVQAQVWGLGRVAALEVPERWGGLIDLPEVLDERAV 4451 Query: 1138 -RLIARITSPRDGEDQIALRGDAVYAPRLVRRT-GEPSDTPLPVREDRTYLVTGGLGAIG 1195 RL+ ++ GEDQ+A+R V+ RLVR E + P T LVTGG G +G Sbjct: 4452 SRLVGVLSGGGSGEDQVAVRSSGVFGRRLVRAPRAEGASAWSPTG---TVLVTGGTGVLG 4508 Query: 1196 LEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMT 1255 VA +LA GA +VLTSRR P +V V+ D AD + L++ Sbjct: 4509 GRVARWLAGAGAERLVLTSRRGPDAPGAAELVEELAGSGVEVSVVACDAADRDALRALLS 4568 Query: 1256 TVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFF 1315 AE L ++H AG + L L +D V K A +L E +L +L F Sbjct: 4569 ---AEAGTLTAVIHTAGVLDDGVLDALTPDRIDSVLRAKAVSAINLHELTAELGIELSAF 4625 Query: 1316 VSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG--MADAESRA 1373 V SS+ WG GQ Y AANA+LD LA + R G+ A S+ +GPWA G ADA A Sbjct: 4626 VLFSSVTGTWGTAGQANYAAANAYLDALAEQRRADGLAATSIAWGPWAEGGMAADAALEA 4685 Query: 1374 RLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELE--- 1429 R+ + GV + A+ + + A V ++W RF P + A L+EL Sbjct: 4686 RMRRGGVPPMKGEAAVNALQRALNANDTVVTVVDVEWERFAPGFTAARASTLLAELPEAQ 4745 Query: 1430 ---SELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADE 1485 + L E+L + +R L+ +R VA V + Sbjct: 4746 RALAPQEGDEGQDDGAVHGRGGHSLAERLAELSAAERDRLLLGLVRKEVAAVLGHAGVES 4805 Query: 1486 IRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQ 1545 I F +LG DSL AVELR R+ G +P TL+ D+P A+YL E+LG Sbjct: 4806 IGAARAFKELGFDSLTAVELRNRLGAVTGLRLPATLIYDYPTSGALAEYLRGELLGTQAV 4865 Query: 1546 TNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDR-WDIDE 1603 + S A DDPIA+VA+SCRFPG PE W+LLA G DAI E PEDR WD + Sbjct: 4866 VS-GPVSNAVAVDDDPIAIVAMSCRFPGGVRTPEDLWQLLATGRDAIGEFPEDRGWDAEA 4924 Query: 1604 FYDP--DPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLER 1661 + P + D P Y R P FFGISPREA+ ++PQQRL+LET WE ER Sbjct: 4925 LFGPQFEQDAP---YAREGGFLYDVADFDPAFFGISPREALAMDPQQRLLLETSWEAFER 4981 Query: 1662 AGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFE 1721 AG P +RGS+ GVF G +Y L+ S D + TGN+ + +SGR+++ G E Sbjct: 4982 AGIDPLSVRGSQAGVFVGTNGQDYLSLV-LNSADGGDGFMSTGNSASVVSGRLSYVFGLE 5040 Query: 1722 GPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGR 1781 GPAV VDTACS++LVA+H A QAL++G+C LALAGGV V+ +P SR R L+ GR Sbjct: 5041 GPAVTVDTACSASLVALHLAVQALRNGECSLALAGGVTVMSTPGAFAEFSRQRGLAEDGR 5100 Query: 1782 CKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGA 1841 K F A+ADG EG G+L+++RLSDA R+G V A++ S+VNQDGAS+GLT PNG + Sbjct: 5101 IKAFAAAADGTGWGEGVGMLLVERLSDARRNGHPVLALVRGSAVNQDGASNGLTAPNGPS 5160 Query: 1842 QQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVK 1901 QQR+I A LA AGL+ D+D +EAHGTGT LGDPIE Q PL +GS+K Sbjct: 5161 QQRVIRAALASAGLAPGDIDAVEAHGTGTKLGDPIEAQALLATYGQDRPADRPLQLGSIK 5220 Query: 1902 TNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNG 1961 +NIGHT++A+G AGL+K+VL++QHGVLPQ+LH + P+PH+ W A + ++ E W G Sbjct: 5221 SNIGHTQAAAGVAGLMKMVLAMQHGVLPQTLHVDEPTPHVDWSAGDIALLTERREWPETG 5280 Query: 1962 RVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSP 2021 R RRAG+SSFG +GTNAH ++E+APP T + L+ ++ Sbjct: 5281 RPRRAGISSFGVSGTNAHTILEQAPPLTEKDEAEAARPE------TGSAVSAWPLAGKTE 5334 Query: 2022 EALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVV-DSVXXXXXXXXXXXX 2080 L E A R + A L DV H+ GR+ F++RA LV D Sbjct: 5335 AGLREQAERLLAHIDAHSELRPVDVGHSLATGRAAFDHRAVLVAGDDRSEFRRALAALAS 5394 Query: 2081 XXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPR 2140 + A VV+G A+LFTGQGSQ GM REL++T PVFA + +AV L Sbjct: 5395 GESVAQVVQGIARPDQQVAFLFTGQGSQRLGMGRELYETYPVFADAL----DAVCARLEL 5450 Query: 2141 PLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAAC 2200 PL DVLF D AD L T++ QPALFAVE+ L RL +SW + PD + GHS+G+ AAA Sbjct: 5451 PLKDVLFGGD---ADRLNETAYTQPALFAVEVALFRLVESWGVRPDFLAGHSIGEIAAAH 5507 Query: 2201 VAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-N 2259 VAGVFSLDD L+ RGR+ +LP GG M+AV A V + E RVS+ A NGP + Sbjct: 5508 VAGVFSLDDACALVEARGRLMQALPTGGVMIAVQASEAEVLPLLTE--RVSIAAINGPQS 5565 Query: 2260 TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLP 2319 V++G D IV+ F D + LA SHAFHS +D +L P +P Sbjct: 5566 VVIAGDEADAVAIVDAFNDR--KSKRLAVSHAFHSPHMDGMLADFRKVAEELSYEAPRIP 5623 Query: 2320 LVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAV 2379 +V N TGA++T + A +W RH R+ V+F + +R + A G +V +E+GP VL+ A Sbjct: 5624 IVSNLTGALVTDEMG-SADFWVRHVREAVRFLDGIRALEAAGVTVYVELGPDGVLSAMAQ 5682 Query: 2380 QVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYP 2438 + AA V +LRKG + I ALA A+ G D+ A + V+LPTY Sbjct: 5683 ECVTGEGAA--FVPALRKGRPEAETITAALAHAHTHGIAVDWQAYFAGTGAQRVDLPTYA 5740 Query: 2439 FQRRRFW----PKASSIAVDG-GTAASGILGSGKDLASGD-TIYTSRLSVKSQPWLADHV 2492 FQR+R+W + +A G G+A +LG+ +L D ++T RLS+++ PWLADHV Sbjct: 5741 FQRQRYWVDSFAEFDDVASAGIGSAGHPLLGAAVELPDSDGFLFTGRLSLRTHPWLADHV 5800 Query: 2493 IYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSV 2549 + TVVVPGA + +A+ A VG ++++ P++LPEK + +++L++ AD Sbjct: 5801 VADTVVVPGAAFVELAVRAGDEVGC-EEVEELVLEAPLVLPEKGAVQLRLSVGGADDQGR 5859 Query: 2550 LSFQIHSRPY-----GERGADWSLNAEGTVDTAGSDPDA-----------AADEQSDPVD 2593 S +HSR G G WS NA G + T GS D A EQ D V Sbjct: 5860 RSVHVHSRVEAADGGGVPGGAWSRNATGLLSTGGSGSDVDSGTVIGEWPPAGAEQVD-VT 5918 Query: 2594 EVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSE 2653 V ERL A L GP + +L +W+ E + + EL+ G Sbjct: 5919 AVRERL------------AAAGLHHGPGFR-TLTEVWVRGEEVFAEARLSDELSASAGRF 5965 Query: 2654 PMHPVLMD 2661 +HP L+D Sbjct: 5966 ALHPTLLD 5973 Score = 1556 bits (4030), Expect = 0.0 Identities = 1010/2486 (40%), Positives = 1358/2486 (54%), Gaps = 135/2486 (5%) Query: 15 AIIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + RFPG AS E+ W LL GR+ I+ P DR WD++ + DP G R Sbjct: 1833 AIVAMSCRFPGGIASPEDLWQLLVTGRDGITGFPADRGWDLDSLYSDDPDREGTSYAREG 1892 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ + FDA FFG+S RE MDPQ R+L+ET W E +GI PTSL S TGVFVG Sbjct: 1893 GFLHEAAEFDASFFGISPREALAMDPQQRLLLETTWETFERAGIDPTSLRGSRTGVFVGS 1952 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 DYL + ++ +E ++ G + + +GR+SY GL+GPAV VDTACSSSLV +H Sbjct: 1953 NAQDYLQLWLNDAD--GLEGHLGTGNAASVVSGRLSYTFGLEGPAVTVDTACSSSLVTLH 2010 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC +ALAG ++ TP FS LA DGR K F AAADG EG G Sbjct: 2011 LAAQALRRGECSMALAGAVTIMSTPGAFTEFSRQRGLAADGRIKAFAAAADGTSWSEGVG 2070 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DA R+G + AV+RG+A+NQDGAS GLT PNG +QQRVI +AL AGL A+ Sbjct: 2071 LLLVERLSDARRNGHPVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIREALADAGLSAAE 2130 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT+LGDPIEAQA G GR ++PL +GS K+NIGH + Sbjct: 2131 VDAVEAHGTGTTLGDPIEAQALLATYGQGRPDDQPLWLGSVKSNIGHTQAVAGAAGIIKM 2190 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP+ L+ + P+P++ W I ++ E W G+PR AGVSSFG++GTNAH Sbjct: 2191 VMAMRHGVLPQTLHIDEPTPYVDWSAGDIALLTEQRAWPETGRPRRAGVSSFGYSGTNAH 2250 Query: 433 VILEEAPAVGTPATTE----PVEDP--RRYSVLPL--SARTPEALVRLAGEYRDWLRAHP 484 ++E+AP T + P P R VLPL S RT AL A R A Sbjct: 2251 AVIEQAPQNAMERTPQGDNLPARTPATRTLPVLPLLVSGRTAPALRAQAERLRPAATALA 2310 Query: 485 QARLA--------DVSHTAGTARAHLEQRAALV--VNSRESAIELLGALADDRPAPGLVR 534 + D+ ++ T+RA LE RA L+ + ++ L ALA PGLV+ Sbjct: 2311 TGTVTNSGALEALDLGYSLATSRAALEHRAVLIGTPSDGQALASRLDALAAGEQVPGLVQ 2370 Query: 535 GESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDA 594 G + A+LFTGQGSQ GM REL++T PVFAE + +AV LE PL +V+F A Sbjct: 2371 GTA-SGGGLAFLFTGQGSQRLGMGRELYETYPVFAEAL----DAVCARLELPLKEVLFGA 2425 Query: 595 DELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFD 654 D + L T QPALFA+E+ L RL +SWG PD V GHS+G+ +AA VAGVF Sbjct: 2426 DG------AALDQTAVTQPALFAIEVALFRLVESWGLRPDFVAGHSIGEIAAAHVAGVFS 2479 Query: 655 VEDGARLIAERGRLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTVLSGP 713 +ED RL+ RGRL +LP GG M AV + + LTD +S+AA NG +V+ Sbjct: 2480 LEDACRLVEARGRLMQALPGGGVMIAVQASEDEVLPLLTDR---VSIAAINGPQSVVI-- 2534 Query: 714 AKDLESAVATLVA-DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNR 772 A D AVA + G + L SHAFHS +D +L+DF + A+ L Y P+ ++ N Sbjct: 2535 AGDEADAVAIAESFTGRKSKHLAVSHAFHSPHMDGMLEDFRAVAEGLSYEAPRIAVVSNL 2594 Query: 773 TGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWP- 831 TG AL +W RH R+ V F +R L +E+GP VL+A A Sbjct: 2595 TG-ALVSDEMSSAEFWVRHVREAVRFLDGIRALEAAGVTTYVELGPGGVLSALAQECVSG 2653 Query: 832 DPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAF-RQPDARKLDLPTYPFEHR 890 D A VL S R ++ + A+A A+ G D+ AF A ++DLPTY F+ + Sbjct: 2654 DGAAFVPVLRSGR---SEAETVVTALAQAHVRGVEVDWAAFFAGTGAERIDLPTYAFQRQ 2710 Query: 891 QFWFSDNRAIDRDTQTASAGSVTPHRTQAV--RLLEDGQIEELAALIDGETVDEQTL-RV 947 ++W +T ++ G V AV R + + E+LA+L+ VDE L V Sbjct: 2711 RYW--------PETVLSTVGPVVAEAVDAVDARFWDAVEREDLASLVAELDVDETPLGEV 2762 Query: 948 LNKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVG-----DDTAAVLEF 1002 + L+A ++R+ RY + W W++V DD+A V Sbjct: 2763 VPALSAWRRERRAQSEVDGWRYRVSWKPLADASTARLSG-SWVVVSPDKGVDDSAVVAGL 2821 Query: 1003 ADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRV- 1061 A G ++V G D R+A AG L A G+AA + LL + Sbjct: 2822 AGR---GAEVRRVVVEAGVD----------RSALAGLL------ADAGSAAGVVSLLGLD 2862 Query: 1062 QHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELP 1120 + L G L +A DA + +P+W +TR V +D +V P Q+ +WG GR AALE+P Sbjct: 2863 ESEGLLGTVGLVQALGDAGVEAPLWCLTRGAVSVGRSDRLVSPVQAQVWGLGRVAALEVP 2922 Query: 1121 HIWGGLADLSGADTEWPRLIARITS--PRDGEDQIALRGDAVYAPRLVRRT---GEPSDT 1175 WGGL DL E R +AR+ GEDQ+A+R V+ RLVR G + T Sbjct: 2923 EHWGGLVDLPEVLDE--RAVARLVGVLAGSGEDQVAVRSSGVFGRRLVRAPRAEGAAAWT 2980 Query: 1176 PLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQ-YA 1234 P T LVTGG G +G VA +LA GA +VLTSRR P + Sbjct: 2981 PTG-----TVLVTGGTGVLGGRVARWLAGAGAERLVLTSRRGPDAPGAAELVEELTTGFG 3035 Query: 1235 CDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGK 1294 +V ++ D AD + L++ AE L ++H AG + L L +D V K Sbjct: 3036 VEVSIVACDAADRDALRALLS---AEAGTLTAVIHTAGVLDDGVLDALTPDRIDSVLRAK 3092 Query: 1295 VWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTA 1354 A +L E +L +L FV SS++ G GQ Y AANAFLD LA + R G+ A Sbjct: 3093 AVSALNLHELTAELDIELSAFVLFSSMSGTVGAAGQANYAAANAFLDALAEQRRADGLAA 3152 Query: 1355 VSVNFGPWAAG--MADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSR 1411 S+ +GPWA G ADA AR+ + GV + AL+ + + + + DW+R Sbjct: 3153 TSLAWGPWAEGGMAADAALEARMRRGGVPPMDAELALSALRQAIGSADAALTIVDFDWAR 3212 Query: 1412 FLPLYQQAGRRAFLSEL-ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNY 1470 F P + L+EL E+ L +L ++ + Sbjct: 3213 FAPGFTAVRAGNLLAELPEAAAVMRGPENADSRPEHADSSLALRLQGMAQADQEPFLLEL 3272 Query: 1471 LRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLS 1529 +R VAEV A++I F ++G DSL AVELR R+ +P TLV D+P + Sbjct: 3273 VRAQVAEVLGHSGAEDIEAGRAFREIGFDSLTAVELRNRLGAAAELRLPATLVYDYPTPA 3332 Query: 1530 DAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGV 1588 A +L E+LG + + V DDPIA+V++SCRFPG PE WELL+ G Sbjct: 3333 ALAVHLRTELLGKQVVVSGPVSKVVD---DDPIAIVSMSCRFPGGVRTPEDLWELLSTGG 3389 Query: 1589 DAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQ 1647 DAI ++P DR WDID YD DP T G +Y R +FFGISPREA+ ++PQ Sbjct: 3390 DAISDLPLDRGWDIDALYDADPSTQGTSYARAGGFLYDAADFDADFFGISPREALAMDPQ 3449 Query: 1648 QRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNAL 1707 QRL+LET WE ERAG P LRGS+ GVF G +Y +L E + +E H TGNA Sbjct: 3450 QRLLLETSWEAFERAGIDPETLRGSQAGVFVGTNGQDYLSVLLEEP-EGLEGHLGTGNAA 3508 Query: 1708 NAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTV 1767 + +SGR+++ G EGPAV VDTACSS+LVA+H A QAL++G+C LALAGGV V+ +P T Sbjct: 3509 SVVSGRLSYVFGLEGPAVTVDTACSSSLVALHWAIQALRNGECSLALAGGVTVMSTPGTF 3568 Query: 1768 VAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQ 1827 + SR R L+ GR K F A+ADG EG G+L+++RLSDA R+G V A++ S++NQ Sbjct: 3569 IEFSRQRGLAEDGRIKAFAAAADGTGWGEGVGMLLVERLSDAERNGHPVLAIVRGSAINQ 3628 Query: 1828 DGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXX 1887 DGAS+GLT PNG +QQR+I A LA AGLS ADVD +EAHGTGT LGDPIE Q Sbjct: 3629 DGASNGLTAPNGPSQQRVIRAALASAGLSAADVDAVEAHGTGTTLGDPIEAQALLATYGQ 3688 Query: 1888 XXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALP 1947 PL +GS+K+NIGHT++A+G AG+IK+VL+++HGVLPQSLH + PSP + W+A Sbjct: 3689 DRPADRPLQLGSIKSNIGHTQAAAGVAGVIKMVLAMEHGVLPQSLHIDAPSPQVDWEAGD 3748 Query: 1948 VRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGT 2007 + ++ E W GR RRAGVSSFGF+GTNAH ++E+AP Sbjct: 3749 IALLTEQRQWPETGRPRRAGVSSFGFSGTNAHTIIEQAPASTE--------TDRAESGSV 3800 Query: 2008 DDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDS 2067 + L LSA+S AL A L A P + ++DV T GRS FE RAALV Sbjct: 3801 EPDFVPLMLSAKSDVALRAQAASLRARLIAAPDMRLSDVGSTLTTGRSAFERRAALVAGG 3860 Query: 2068 VXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTV 2127 + AG+V G V A+LFTGQGSQ GM REL++ PVFA + Sbjct: 3861 REGLLAGLEALADGGSAAGLVEGSPV-SGKLAFLFTGQGSQRLGMGRELYEAYPVFADAL 3919 Query: 2128 RQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDV 2187 +AV L PL+DVLF D A LL T++ QPALFAVE+ L RL +SW + PD Sbjct: 3920 ----DAVCVRLELPLMDVLFGAD---AGLLNETAYTQPALFAVEVALFRLVESWGLRPDF 3972 Query: 2188 VLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF 2247 + GHS+G+ AAA VAGV SLDD L+ RGR+ G+LP GG M+AV A + V + + Sbjct: 3973 LAGHSIGEIAAAHVAGVLSLDDACALVEARGRLMGALPAGGVMIAVQASEDEVLPLLTD- 4031 Query: 2248 PRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXX 2306 RVS+ A NGP + V++G D IVE F G + L+ SHAFHS +D +L+ Sbjct: 4032 -RVSIAAINGPQSVVIAGDEADAVAIVESF--TGRKSKRLSVSHAFHSPHMDGMLEDFRV 4088 Query: 2307 XXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM 2366 P +P+V N TGA++T + A +W RH R+ V+F + +R + A G + + Sbjct: 4089 VAEGLSYDAPRIPVVSNLTGALVTDEMG-SADFWVRHVREAVRFLDGIRALEAAGVTTYV 4147 Query: 2367 EIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR 2426 E+GP VL+ A + E AA V LRKG + + L A+V G D+ +V+ Sbjct: 4148 ELGPDGVLSAMAQECVTEGGAA--FVPVLRKGRPEAETVMATLGQAHVRGVAVDWHSVYG 4205 Query: 2427 QPRRPVELPTYPFQRRRFWPKASSIA 2452 + V+LPTY FQR+R+WP ASS A Sbjct: 4206 TGAQRVDLPTYSFQRQRYWPAASSTA 4231 Score = 798 bits (2062), Expect = 0.0 Identities = 564/1502 (37%), Positives = 768/1502 (51%), Gaps = 93/1502 (6%) Query: 1004 DALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAG------DGAAAP--- 1054 DAL G H LPG A A L + A AG + A DG AAP Sbjct: 1249 DALVNGLLGH----LPGEVARYADLAELAAAVEAGAATPDAVFAAYARSDDDGPAAPDVS 1304 Query: 1055 -----MRDLLRVQHRTLGGLRRLFRA---ANDAELRSPIWLVTRDGQRVTDTDTVV-PEQ 1105 + + H L ++ F A D + + ++TR D DTV P Sbjct: 1305 APDVSAQAVHAATHDALALVQTWFGEEPFAGDRFAATRLVVLTRGAVAAGDGDTVTDPAH 1364 Query: 1106 SCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRL 1165 + +WG R+A E P L D G + L A + GE Q+ALR +V+A RL Sbjct: 1365 AAVWGLLRSAQSEYPDRLL-LIDTDGVEDSVHALPAVLAV---GEPQLALRAGSVHALRL 1420 Query: 1166 VR---RTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYL-ASHGAGHVVLTSRREPXXX 1221 R T E + P T L+TG G +G +A L A HG H++L RR Sbjct: 1421 ARVAAATPEDAAAPTQYAPGSTVLITGAGGMLGGLIARRLVAEHGVRHLLLVGRRGAAAP 1480 Query: 1222 XXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSG 1281 + V DVAD ++ ++ + AE PL +VH AG + ++ Sbjct: 1481 GAEQLSAELAEAGASVTWAACDVADRDALSAVLHAIPAE-HPLGAVVHTAGVLDDGVIAS 1539 Query: 1282 LDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLD 1341 L + V KV A +L E L DL FV SSI V+GG GQ Y AAN FLD Sbjct: 1540 LTPERLSAVLRPKVDAACNLHELTRHL--DLTAFVLFSSIGGVFGGPGQGNYAAANVFLD 1597 Query: 1342 GLAWRLRERGVTAVSVNFGPWA-----AGMADAESRARLEQRGVRTLSPAEALAGMADVV 1396 LA R +G+ A S+ + WA AG D +R+ + G+ L+ AE L + D+ Sbjct: 1598 ALAQHRRSQGLAATSLAWALWADSTGMAGSLDEADISRMRRGGLPPLTTAEGLE-LFDLA 1656 Query: 1397 -----AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXL 1451 A PV + + D + Q L L L Sbjct: 1657 HRIDEAAPV---LMRADLTALRTQAQAGTMSPLLRGLVR--VPARRSASGAAGTGGESGL 1711 Query: 1452 VEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADE-IRDEAGFFDLGMDSLMAVELRRRIE 1510 E+L +R + + +R VA + F +LG DSL AVELR + Sbjct: 1712 RERLAGLSAAERDRTLLDLVRKQVAAALGYPGPSAVEPGRSFKELGFDSLTAVELRNLLG 1771 Query: 1511 QGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTART---------DDP 1561 G+ +P TLV D+P + A YL E++G A +A DDP Sbjct: 1772 DATGRRLPATLVFDYPTATALAGYLREEIIGDLADAVTAPALVPSAAVAGAGAGADDDDP 1831 Query: 1562 IAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRX 1619 IA+VA+SCRFPG PE W+LL G D I P DR WD+D Y DPD G +Y R Sbjct: 1832 IAIVAMSCRFPGGIASPEDLWQLLVTGRDGITGFPADRGWDLDSLYSDDPDREGTSYARE 1891 Query: 1620 XXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTG 1679 FFGISPREA+ ++PQQRL+LET WE ERAG P+ LRGSRTGVF G Sbjct: 1892 GGFLHEAAEFDASFFGISPREALAMDPQQRLLLETTWETFERAGIDPTSLRGSRTGVFVG 1951 Query: 1680 VAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVH 1739 A +Y L ++ D +E H TGNA + +SGR+++ G EGPAV VDTACSS+LV +H Sbjct: 1952 SNAQDYLQLWLNDA-DGLEGHLGTGNAASVVSGRLSYTFGLEGPAVTVDTACSSSLVTLH 2010 Query: 1740 QACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCG 1799 A QAL+ G+C +ALAG V ++ +P SR R L+ GR K F A+ADG SEG G Sbjct: 2011 LAAQALRRGECSMALAGAVTIMSTPGAFTEFSRQRGLAADGRIKAFAAAADGTSWSEGVG 2070 Query: 1800 VLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGAD 1859 +L+++RLSDA R+G V AV+ ++VNQDGAS+GLT PNG +QQR+I LA AGLS A+ Sbjct: 2071 LLLVERLSDARRNGHPVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIREALADAGLSAAE 2130 Query: 1860 VDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKV 1919 VD +EAHGTGT LGDPIE Q PL +GSVK+NIGHT++ +GAAG+IK+ Sbjct: 2131 VDAVEAHGTGTTLGDPIEAQALLATYGQGRPDDQPLWLGSVKSNIGHTQAVAGAAGIIKM 2190 Query: 1920 VLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAH 1979 V++++HGVLPQ+LH + P+P++ W A + ++ E W GR RRAGVSSFG++GTNAH Sbjct: 2191 VMAMRHGVLPQTLHIDEPTPYVDWSAGDIALLTEQRAWPETGRPRRAGVSSFGYSGTNAH 2250 Query: 1980 VLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV-LALSARSPEALVELARRYDDWLSA- 2037 ++E+A PQ T P + L +S R+ AL A R +A Sbjct: 2251 AVIEQA-PQNAMERTPQGDNLPARTPATRTLPVLPLLVSGRTAPALRAQAERLRPAATAL 2309 Query: 2038 -------TPGLDIADVCHTAGVGRSHFEYRAALV---VDSVXXXXXXXXXXXXXXTPAGV 2087 + L+ D+ ++ R+ E+RA L+ D P G+ Sbjct: 2310 ATGTVTNSGALEALDLGYSLATSRAALEHRAVLIGTPSDGQALASRLDALAAGEQVP-GL 2368 Query: 2088 VRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLF 2147 V+G A+LFTGQGSQ GM REL++T PVFA+ + +AV L PL +VLF Sbjct: 2369 VQGT-ASGGGLAFLFTGQGSQRLGMGRELYETYPVFAEAL----DAVCARLELPLKEVLF 2423 Query: 2148 ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSL 2207 D D T+ QPALFA+E+ L RL +SW + PD V GHS+G+ AAA VAGVFSL Sbjct: 2424 GADGAALD---QTAVTQPALFAIEVALFRLVESWGLRPDFVAGHSIGEIAAAHVAGVFSL 2480 Query: 2208 DDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-NTVLSGPG 2266 +D RL+ RGR+ +LP GG M+AV A + V + + RVS+ A NGP + V++G Sbjct: 2481 EDACRLVEARGRLMQALPGGGVMIAVQASEDEVLPLLTD--RVSIAAINGPQSVVIAGDE 2538 Query: 2267 EDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTG 2326 D I E F G + LA SHAFHS +D +L+ P + +V N TG Sbjct: 2539 ADAVAIAESF--TGRKSKHLAVSHAFHSPHMDGMLEDFRAVAEGLSYEAPRIAVVSNLTG 2596 Query: 2327 AVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHM 2386 A+++ + A++W RH R+ V+F + +R + A G + +E+GP VL+ A + Sbjct: 2597 ALVSDEMS-SAEFWVRHVREAVRFLDGIRALEAAGVTTYVELGPGGVLSALAQECVSGDG 2655 Query: 2387 AAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFW 2445 AA V LR G ++ + ALA A+V G D+AA ++LPTY FQR+R+W Sbjct: 2656 AA--FVPVLRSGRSEAETVVTALAQAHVRGVEVDWAAFFAGTGAERIDLPTYAFQRQRYW 2713 Query: 2446 PK 2447 P+ Sbjct: 2714 PE 2715 Score = 772 bits (1993), Expect = 0.0 Identities = 524/1450 (36%), Positives = 735/1450 (50%), Gaps = 98/1450 (6%) Query: 1549 RQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDIDEFYD 1606 R+ +T +PIA+V +SCRFPG PE W L+ G DAI P +R WDI+ YD Sbjct: 24 RRNQELTDAAREPIAIVGMSCRFPGGVSSPEDLWRLVESGGDAISGFPVNRGWDIESLYD 83 Query: 1607 PDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP 1666 PDPD G TY R P FFGISPREA+ ++PQQRL+LET WE ERAG P Sbjct: 84 PDPDHEGTTYARDGGFLHEAADFDPAFFGISPREALAMDPQQRLLLETTWEVFERAGIDP 143 Query: 1667 SDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVA 1726 + LRGSR GVF G +AN Y S + D +E H +TG A + +SGR+A+ G EGPA Sbjct: 144 ASLRGSRAGVFVGASANAYG-AGSHDLPDGVEGHLLTGTASSVLSGRLAYVFGLEGPAAT 202 Query: 1727 VDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFD 1786 +DTACSS+ VA+H A QAL+ G+C LALA GV VL P V SR R LSP GRC++F Sbjct: 203 IDTACSSSSVALHMAVQALRQGECSLALAAGVTVLAGPDVFVEFSRQRGLSPDGRCRSFA 262 Query: 1787 ASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLI 1846 SADG SEG GVL+++RLSDA R+G + AV+ S+VNQDGAS+GLT PNG AQQ++I Sbjct: 263 ESADGTGWSEGAGVLLVERLSDARRNGHHILAVVRGSAVNQDGASNGLTAPNGPAQQKVI 322 Query: 1847 EATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGH 1906 L A L+ AD+D +EAHGTGT LGDPIE Q PL +GS+K+N+GH Sbjct: 323 RQALESARLTPADIDAVEAHGTGTTLGDPIEAQALLATYGQGRTDGRPLWLGSLKSNLGH 382 Query: 1907 TESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRA 1966 T++A+G AG+IK+V++++HGVLP++LH + P+ H+ W V ++ EPV W GR RR Sbjct: 383 TQNAAGVAGIIKMVMAMRHGVLPRTLHVDEPTSHVDWSTGAVALLTEPVEWPETGRPRRV 442 Query: 1967 GVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL--ALSARSPEAL 2024 GVS+FG +GTN H ++E+AP P+ L LSA+ +AL Sbjct: 443 GVSAFGVSGTNVHTIIEQAP-----APAPAPVADDTSEPAPAARPKALPWLLSAKGRDAL 497 Query: 2025 VELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTP 2084 + A + + P L D+ + VGR FE RAA+V + Sbjct: 498 RDRAAQLLAYAEEHPDLRPVDIAGSLAVGRPSFEDRAAVVAADREGLLAGLAALADGGSA 557 Query: 2085 AGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLD 2144 G+V+G A+LFTGQGSQ GM REL++T PVFAQ + +AV + L PL + Sbjct: 558 TGLVKGSSQLVGKLAFLFTGQGSQRLGMGRELYETYPVFAQAL----DAVCERLELPLKN 613 Query: 2145 VLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGV 2204 VLF TD D TS+ QPALFAVE+ L RL +SW ++PD + GHS+G+ AAA VAGV Sbjct: 614 VLFGTDSAALD---ETSYTQPALFAVEVALFRLVESWGLKPDFLAGHSIGEIAAAHVAGV 670 Query: 2205 FSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-NTVLS 2263 FSLDD L++ RGR+ G+LP GG M+AV A + V + + RVS+ A NGP + V++ Sbjct: 671 FSLDDACALVSARGRLMGALPGGGVMIAVQASEDEVLPLLTD--RVSIAAINGPQSVVIA 728 Query: 2264 GPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCN 2323 G D I E F D + L SHAFHS +D +L+ P +P+V N Sbjct: 729 GDEADAVAIAESFADR--KSKRLTVSHAFHSPHMDGMLEDFRVVAEGLSYEAPRIPVVSN 786 Query: 2324 RTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWP 2383 TGA+++ + A +W RH R+ V+F + +RT+ A G + +E+GP VL+ A Sbjct: 787 LTGALVSDEMG-SADFWVRHVRETVRFLDGIRTLEAAGVTKYVELGPDGVLSALAQDCVS 845 Query: 2384 EHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRR 2442 + + LRK + +A ALASA+V G D+ A + V+LPTYPFQR+ Sbjct: 846 GEDSV--FIPVLRKARPEAETVATALASAHVHGIPVDWRAYFAGTGAQRVDLPTYPFQRQ 903 Query: 2443 RFWPKASSIAVDGGT-----AASGILGSGKDLASGD-TIYTSRLSVKSQPWLADHVIYGT 2496 R+W + A D G A +LG+ LA + ++T RL S PWLADH + T Sbjct: 904 RYWIEPGGRAGDVGAAGLEEAGHPLLGAAVPLADSEGFLFTGRLGRTSHPWLADHAVMDT 963 Query: 2497 VVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTL--HPADGGSVLS 2551 V++PG + +A+ A VG ++++ P++LPE+ + ++Q+ + ADG + Sbjct: 964 VLLPGTAFVDLAVRAGDQVGCDV-VEELTLEAPLVLPERGAVQIQMHVGAPDADGTGRRT 1022 Query: 2552 FQIHSRPY-GERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFET 2610 F + SR G W+ +A G + + P A PV E + + L+ Sbjct: 1023 FTLSSRTQDGAADEPWTRHAGGVLAHGAAQPAFA------PVQWPPAGAEPIPTESLYAD 1076 Query: 2611 FADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXX 2670 A++ + +GP + G L + W ++ + E A +HP L+D Sbjct: 1077 LAEVGMGYGPAFRG-LTAAWRHGESVYVEVALPEETASTARDFGLHPALLDAALHALGLG 1135 Query: 2671 XXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGG 2730 E LP + VTL R H + + LE D G Sbjct: 1136 VLGGVEGEGR-----LPFAWSGVTLHAAGADAL----RVHLAPAGAHG--VRLEIADAAG 1184 Query: 2731 RALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGF--- 2787 + + + V R E +R ++ W +P + G W + G Sbjct: 1185 APVATV-DSLVLRTVSEEQVRAARTAYHESVFRAEWTALPTAAESAATHGRWAVLGAADA 1243 Query: 2788 -----DELAAKVPGCVP--IDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXX 2840 D L + G +P + R DL L + A R G Sbjct: 1244 GDSPRDALVNGLLGHLPGEVARYADLAELAAAVEAGAATPDAVFAAYARSDDDGPAAPDV 1303 Query: 2841 XXXXXXXXXXXITNLLSAVHAAQGPSVKL----------------PGGLWIVTEHGVACE 2884 AVHAA ++ L L ++T VA Sbjct: 1304 SAPDVS---------AQAVHAATHDALALVQTWFGEEPFAGDRFAATRLVVLTRGAVAAG 1354 Query: 2885 SGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAV 2943 G+ V DP AA+WG R+ +E P L+D DG ++V + EP++A+ Sbjct: 1355 DGDTVTDPAHAAVWGLLRSAQSEYPD-RLLLIDTDGVEDSVHALPAVL---AVGEPQLAL 1410 Query: 2944 RQGKLLASRL 2953 R G + A RL Sbjct: 1411 RAGSVHALRL 1420 Score = 659 bits (1700), Expect = 0.0 Identities = 383/890 (43%), Positives = 518/890 (58%), Gaps = 32/890 (3%) Query: 15 AIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G + RFPG S+ E+ W L+ G +AIS P +R WDIE +DPDP G R Sbjct: 38 AIVGMSCRFPGGVSSPEDLWRLVESGGDAISGFPVNRGWDIESLYDPDPDHEGTTYARDG 97 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ + FD FFG+S RE MDPQ R+L+ET W E +GI P SL S GVFVG Sbjct: 98 GFLHEAADFDPAFFGISPREALAMDPQQRLLLETTWEVFERAGIDPASLRGSRAGVFVGA 157 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 + + Y G S +L +E ++ GT+++ +GR++Y GL+GPA +DTACSSS VA+H Sbjct: 158 SANAY-GAGSHDLP-DGVEGHLLTGTASSVLSGRLAYVFGLEGPAATIDTACSSSSVALH 215 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC LALA G VL P + FS L+PDGRC++F +ADG EG G Sbjct: 216 MAVQALRQGECSLALAAGVTVLAGPDVFVEFSRQRGLSPDGRCRSFAESADGTGWSEGAG 275 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V++V+RL DA R+G I AV+RGSA+NQDGAS GLT PNG AQQ+VI AL+ A L PAD Sbjct: 276 VLLVERLSDARRNGHHILAVVRGSAVNQDGASNGLTAPNGPAQQKVIRQALESARLTPAD 335 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 + +EAHGTGT+LGDPIEAQA G GR PL +GS K+N+GH + Sbjct: 336 IDAVEAHGTGTTLGDPIEAQALLATYGQGRTDGRPLWLGSLKSNLGHTQNAAGVAGIIKM 395 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP+ L+ + P+ H+ W + ++ E V W G+PR GVS+FG +GTN H Sbjct: 396 VMAMRHGVLPRTLHVDEPTSHVDWSTGAVALLTEPVEWPETGRPRRVGVSAFGVSGTNVH 455 Query: 433 VILEEAPAVGTPATTEPVEDP---RRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQAR 487 I+E+APA + +P R LP LSA+ +AL A + + HP R Sbjct: 456 TIIEQAPAPAPAPVADDTSEPAPAARPKALPWLLSAKGRDALRDRAAQLLAYAEEHPDLR 515 Query: 488 LADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLF 547 D++ + R E RAA+V RE + L ALAD A GLV+G S K A+LF Sbjct: 516 PVDIAGSLAVGRPSFEDRAAVVAADREGLLAGLAALADGGSATGLVKGSSQLVGKLAFLF 575 Query: 548 TGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRH 607 TGQGSQ GM REL++T PVFA+ + +AV + LE PL +V+F D + L Sbjct: 576 TGQGSQRLGMGRELYETYPVFAQAL----DAVCERLELPLKNVLFGTD------SAALDE 625 Query: 608 TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGR 667 T+Y QPALFAVE+ L RL +SWG +PD + GHS+G+ +AA VAGVF ++D L++ RGR Sbjct: 626 TSYTQPALFAVEVALFRLVESWGLKPDFLAGHSIGEIAAAHVAGVFSLDDACALVSARGR 685 Query: 668 LFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVA 726 L G+LP GG M AV + + LTD +S+AA NG +V+ + A+A A Sbjct: 686 LMGALPGGGVMIAVQASEDEVLPLLTDR---VSIAAINGPQSVVIAGDEADAVAIAESFA 742 Query: 727 DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGA 786 D + L SHAFHS +D +L+DF A+ L Y P+ ++ N TG AL Sbjct: 743 DR-KSKRLTVSHAFHSPHMDGMLEDFRVVAEGLSYEAPRIPVVSNLTG-ALVSDEMGSAD 800 Query: 787 YWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATA--LAAWPDPATTPQVLASLR 844 +W RH R+ V F +RTL +E+GP VL+A A + D P VL R Sbjct: 801 FWVRHVRETVRFLDGIRTLEAAGVTKYVELGPDGVLSALAQDCVSGEDSVFIP-VLRKAR 859 Query: 845 PTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFW 893 P + + A+A+A+ G D+RA F A+++DLPTYPF+ +++W Sbjct: 860 P---EAETVATALASAHVHGIPVDWRAYFAGTGAQRVDLPTYPFQRQRYW 906 Score = 181 bits (460), Expect = 1e-42 Identities = 130/371 (35%), Positives = 173/371 (46%), Gaps = 25/371 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG G +G A +LA GA +VLTSRR PD + E + A D Sbjct: 4499 LVTGGTGVLGGRVARWLAGAGAERLVLTSRRGPDAPGAAELVEELAGSGVEVSVVACDAA 4558 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXXX 3415 D + LL+ AE L + H AGVLDD +L A P+R + L KA A H Sbjct: 4559 DRDALRALLS---AEAGTLTAVIHTAGVLDDGVLDALTPDRIDSVLRAKAVSAINLHELT 4615 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQANYA ANA LD L +RRA GL AT I +GPW +G Sbjct: 4616 AELGIELSAFVLFSSVTGTWGTAGQANYAAANAYLDALAEQRRADGLAATSIAWGPWAEG 4675 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP 3535 GMA+ A A + G+ P+ AA++AL + TV+ W+R A +AR Sbjct: 4676 GMAADAALEARMRRGGVPPMKGEAAVNALQRALNANDTVVTVVDVEWERFAPGFTAARAS 4735 Query: 3536 ILDLVLPSA----------------AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQ 3579 L LP A A G L ++L E+ +R + +++EV Sbjct: 4736 TLLAELPEAQRALAPQEGDEGQDDGAVHGRGGHSLAERLAELSAAERDRLLLGLVRKEVA 4795 Query: 3580 NFLRLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAE 3637 L A + A+ F +LG DSL A+ELRNRL + G + AT ++DYPT G LAE Sbjct: 4796 AVLGHAGVESIGAARAFKELGFDSLTAVELRNRLGAVTG--LRLPATLIYDYPTSGALAE 4853 Query: 3638 YLVGQLPDAEA 3648 YL G+L +A Sbjct: 4854 YLRGELLGTQA 4864 Score = 176 bits (446), Expect = 6e-41 Identities = 126/362 (34%), Positives = 170/362 (46%), Gaps = 21/362 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHTYAADV 3356 L+TGG G +G A +LA GA +VLTSRR PD A ++E+T + A D Sbjct: 2986 LVTGGTGVLGGRVARWLAGAGAERLVLTSRRGPDAPGAAELVEELTTGFGVEVSIVACDA 3045 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXX 3414 D + LL+ AE L + H AGVLDD +L A P+R + L KA A H Sbjct: 3046 ADRDALRALLS---AEAGTLTAVIHTAGVLDDGVLDALTPDRIDSVLRAKAVSALNLHEL 3102 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQANYA ANA LD L +RRA GL AT + +GPW + Sbjct: 3103 TAELDIELSAFVLFSSMSGTVGAAGQANYAAANAFLDALAEQRRADGLAATSLAWGPWAE 3162 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 GGMA+ A A + G+ P+D AL AL + I + T++ +W R A + R Sbjct: 3163 GGMAADAALEARMRRGGVPPMDAELALSALRQAIGSADAALTIVDFDWARFAPGFTAVRA 3222 Query: 3535 PILDLVLPSAAGEATG-----------DSELLKQLMEIPIPQRAGFVTEFLQREVQNFL- 3582 L LP AA G DS L +L + + F+ E ++ +V L Sbjct: 3223 GNLLAELPEAAAVMRGPENADSRPEHADSSLALRLQGMAQADQEPFLLELVRAQVAEVLG 3282 Query: 3583 -RLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 A A F ++G DSL A+ELRNRL + + + AT V+DYPT LA +L Sbjct: 3283 HSGAEDIEAGRAFREIGFDSLTAVELRNRLGA--AAELRLPATLVYDYPTPAALAVHLRT 3340 Query: 3642 QL 3643 +L Sbjct: 3341 EL 3342 Score = 171 bits (432), Expect = 3e-39 Identities = 159/474 (33%), Positives = 207/474 (43%), Gaps = 31/474 (6%) Query: 1087 LVTRDGQRVTDTDTVVPE--QSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARIT 1144 +VTR G T DT V + + +WG RAA E P + L DL GAD L I Sbjct: 6200 VVTR-GAVATGRDTEVEDLAHAPVWGLLRAAQTEHPDRFV-LVDLDGADASVRALPGAIA 6257 Query: 1145 SPRDGEDQIALRGDAVYAPRLVRR-----TGEPSDTPLPVREDRTYLVTGGLGAI-GLEV 1198 S E ++A+R +YAPRLVR TG+ + R T L+TG G + GL Sbjct: 6258 SQ---ESELAVRDGVLYAPRLVRVGAEAVTGDTGGRRIDPRG--TVLITGASGGLAGLFA 6312 Query: 1199 AGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVA 1258 +A HG H++LTSRR V DVAD +A L+ +V Sbjct: 6313 RHLVAEHGVRHLLLTSRRGAAAEGAAQLADELVALGAQVTWAACDVADRDALAALLASVP 6372 Query: 1259 AELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVST 1318 AE PL +VH A + + L VDRV K A HL E DL DL FV Sbjct: 6373 AE-QPLTAVVHTAAVLDDGVVDLLTPERVDRVLRPKAEAALHLHELTKDL--DLSAFVLF 6429 Query: 1319 SSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA--AGMADAESRARLE 1376 S+ A GG GQ Y AAN FLD LA RG+TA+S+ +G WA GMA + A L Sbjct: 6430 SAAAGTLGGAGQANYAAANVFLDALARHRTARGLTALSLVWGMWAEERGMAGRLTEAELG 6489 Query: 1377 QRGVRTLSPAEALAGM----ADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSEL---- 1428 + G ++P A G+ A + A V +ID G L Sbjct: 6490 RAGRGGVAPLSATEGLALFDAALAADEAVLVPVRIDVPTLRARAADGGIHPMFRGLVRTP 6549 Query: 1429 --ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRV-DADE 1485 S L QL + V +R+ + + +R VA V A+ Sbjct: 6550 VRRSAQSAGRAAGTVPTDGAGERTLARQLAELSVAERERTVLDLVRGQVAAVLGYGSAEH 6609 Query: 1486 IRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEV 1539 I E F +LG DSL AVELR R+ G +P TL+ D+P + A +LL EV Sbjct: 6610 IGGEQAFKELGFDSLTAVELRNRLGAAGGLRLPATLIYDYPNPAALAQHLLSEV 6663 Score = 132 bits (332), Expect = 1e-27 Identities = 118/378 (31%), Positives = 165/378 (43%), Gaps = 31/378 (8%) Query: 3298 LITGGLGAI-GLHTAAYLAQLGAGDIVLTSRRDPD-ESAQRAIDEITERHKCRIHTYAAD 3355 LITG G + GL +A+ G ++LTSRR E A + DE+ ++ A D Sbjct: 6299 LITGASGGLAGLFARHLVAEHGVRHLLLTSRRGAAAEGAAQLADELVALG-AQVTWAACD 6357 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 V D +A LLA + AE PL + H A VLDD ++ PER L PKA A H Sbjct: 6358 VADRDALAALLASVPAE-QPLTAVVHTAAVLDDGVVDLLTPERVDRVLRPKAEAALHLHE 6416 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWG-Q 3474 GQANYA AN LD L R A+GL A + +G W + Sbjct: 6417 LTKDLDLSAFVLFSAAAGTLGGAGQANYAAANVFLDALARHRTARGLTALSLVWGMWAEE 6476 Query: 3475 GGMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKAN--WQRAAKVLG 3530 GMA +EA G+ PL + L +A ++ + RA G Sbjct: 6477 RGMAGRLTEAELGRAGRGGVAPLSATEGLALFDAALAADEAVLVPVRIDVPTLRARAADG 6536 Query: 3531 SARPPILDLV----------LPSAAG----EATGDSELLKQLMEIPIPQRAGFVTEFLQR 3576 P LV AAG + G+ L +QL E+ + +R V + ++ Sbjct: 6537 GIHPMFRGLVRTPVRRSAQSAGRAAGTVPTDGAGERTLARQLAELSVAERERTVLDLVRG 6596 Query: 3577 EVQNFLRLASPP--AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGG 3634 +V L S F +LG DSL A+ELRNRL + G + AT ++DYP Sbjct: 6597 QVAAVLGYGSAEHIGGEQAFKELGFDSLTAVELRNRLGA--AGGLRLPATLIYDYPNPAA 6654 Query: 3635 LAEYLVGQLPDAEAPETA 3652 LA++L+ ++ AP+TA Sbjct: 6655 LAQHLLSEV----APDTA 6668 Score = 127 bits (318), Expect = 4e-26 Identities = 115/367 (31%), Positives = 161/367 (43%), Gaps = 21/367 (5%) Query: 3298 LITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 LITG G +G L +A+ G ++L RR + + A DV Sbjct: 1444 LITGAGGMLGGLIARRLVAEHGVRHLLLVGRRGAAAPGAEQLSAELAEAGASVTWAACDV 1503 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D ++ +L I AE PL + H AGVLDD ++++ PER L PK A + Sbjct: 1504 ADRDALSAVLHAIPAE-HPLGAVVHTAGVLDDGVIASLTPERLSAVLRPKVDAACNLHEL 1562 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG- 3475 PGQ NYA AN LD L RR+QGL AT + + W Sbjct: 1563 TRHLDLTAFVLFSSIGGVFGGPGQGNYAAANVFLDALAQHRRSQGLAATSLAWALWADST 1622 Query: 3476 GMASS--EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQ--RAAKVLGS 3531 GMA S EA + + GL PL + L +++A+ R G+ Sbjct: 1623 GMAGSLDEADISRMRRGGLPPLTTAEGLELFDLAHRIDEAAPVLMRADLTALRTQAQAGT 1682 Query: 3532 ARPPILDLV-LP---SAAGEA--TGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA 3585 P + LV +P SA+G A G+S L ++L + +R + + ++++V L Sbjct: 1683 MSPLLRGLVRVPARRSASGAAGTGGESGLRERLAGLSAAERDRTLLDLVRKQVAAALGYP 1742 Query: 3586 SPPAA--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL---- 3639 P A F +LG DSL A+ELRN L G + + AT VFDYPT LA YL Sbjct: 1743 GPSAVEPGRSFKELGFDSLTAVELRNLLGDATGRR--LPATLVFDYPTATALAGYLREEI 1800 Query: 3640 VGQLPDA 3646 +G L DA Sbjct: 1801 IGDLADA 1807 Score = 39.7 bits (91), Expect = 9.1 Identities = 55/223 (24%), Positives = 80/223 (35%), Gaps = 27/223 (12%) Query: 2756 DATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQ 2815 DA+ + W V P DD+ ++AG A+V V ++ D L +L+ Sbjct: 2793 DASTARLSGSWVVVSPDKGVDDSA---VVAGLAGRGAEVRRVV-VEAGVDRSALAGLLAD 2848 Query: 2816 AHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWI 2875 A + AG ++ + G + + V A V+ P LW Sbjct: 2849 AGS-AAGVVSLLGLDESEG-----------------LLGTVGLVQALGDAGVEAP--LWC 2888 Query: 2876 VTEHGVAC-ESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXP 2934 +T V+ S V PVQA +WG GR E P LVD + Sbjct: 2889 LTRGAVSVGRSDRLVSPVQAQVWGLGRVAALEVPEHWGGLVDLPEVLDERAVARLVGVLA 2948 Query: 2935 GIQEPEIAVRQGKLLASRLL--PWARSGHLTLPRGGDFVLAPT 2975 G E ++AVR + RL+ P A P G V T Sbjct: 2949 GSGEDQVAVRSSGVFGRRLVRAPRAEGAAAWTPTGTVLVTGGT 2991 >tr|D3C7A9|D3C7A9_9ACTO Tax_Id=648999 SubName: Full=Mycocerosate synthase, 6-deoxyerythronolide-B synthase; EC=2.3.1.111; EC=2.3.1.94;[Micromonospora sp. L5] Length = 9937 Score = 1639 bits (4244), Expect = 0.0 Identities = 1078/2711 (39%), Positives = 1441/2711 (53%), Gaps = 115/2711 (4%) Query: 15 AIIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + R+PG AS E+ W L+ G +AI P DR WD++ +DPD G+ TR Sbjct: 38 AIVAMSCRYPGGVASPEQLWDLVAAGGDAIGGFPTDRGWDLDNLYDPDADRAGRSTTREG 97 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE MDPQ R+L+ET+W A EH+GIAP S+ GVFVG Sbjct: 98 GFLYDAADFDAEFFGISPREAVAMDPQQRLLLETSWEAFEHAGIAPASMRGQKVGVFVGT 157 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 A + Y GM E Y+ GT+ + +GRI+Y LGL+GPAV VDTACSSSLVA+H Sbjct: 158 AANGY-GMGPQSEAEGADEGYLLTGTATSVVSGRIAYALGLEGPAVTVDTACSSSLVALH 216 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 ACQALR + DLALAGG V+ TP + FS LAPDGRCK+F AAADG EG G Sbjct: 217 LACQALRQGDFDLALAGGVCVMATPGPFVGFSRQRGLAPDGRCKSFAAAADGTGWSEGVG 276 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DA R G I AVIRGSA+NQDGAS GLT PNG AQQRVI AL A L AD Sbjct: 277 ILLVERLSDAQRKGHPILAVIRGSAVNQDGASNGLTAPNGPAQQRVIRQALANARLTTAD 336 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R + PLL+GS K+NIGH + Sbjct: 337 VDAVEAHGTGTVLGDPIEAQALLATYGRDRPADRPLLLGSIKSNIGHSQSAAGVAGVIKM 396 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + +P L+ + P+P + W + +V E+ PW +PR A VSSFG +GTNAH Sbjct: 397 VMAMRHGLVPSTLHVDEPTPKVDWSAGEVSLVTESTPWPATDRPRRAAVSSFGISGTNAH 456 Query: 433 VILEEAPAVGTPATTEPVE-DPRRYSVLP-----LSARTPEALVRLAGEYRDWLRAHPQA 486 I+EE P TP EP + P LP LSAR+ AL AG + WL Sbjct: 457 TIIEEPP---TPDAVEPADAGPAPTVALPAVPVLLSARSEAALGAQAGRWTRWLEDDEAL 513 Query: 487 RLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWL 546 R DV ++ +R+ LE RA L RE + L ALA +P+ LV G++ + A L Sbjct: 514 RTVDVGWSSVVSRSALEHRAVLTATDREELLAGLRALAAGQPSGALVAGQAADRGPLAVL 573 Query: 547 FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLR 606 F+GQG+Q GM REL+ PVFA + + + +L +PL +V+F A E + E L Sbjct: 574 FSGQGAQRAGMGRELYAEFPVFAAALDEVCAQLDALLPRPLKEVLF-APEGSAEAEL-LD 631 Query: 607 HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERG 666 T + Q LFAVE+ L RL +S+G PD+V GHS+G+ +AA VAGV + D L+A RG Sbjct: 632 RTVFTQAGLFAVEVALFRLVESFGVAPDMVGGHSIGEVTAAHVAGVLSLADACELVAARG 691 Query: 667 RLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLV 725 RL +LPAGG M AV A D + VAA NG + V+SG + L+ Sbjct: 692 RLMQALPAGGGMLAVAAAEADVLATLDGSTGVGVAAVNGPTSVVVSGAVEALDEVERVWR 751 Query: 726 ADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDG 785 GVR L SHAFHS L++P+LD+F L + P ++ N TG+ Sbjct: 752 GRGVRTRRLSVSHAFHSPLMEPMLDEFRVVLDGLTFEAPALPVVSNVTGALADVDEIRSA 811 Query: 786 AYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATA--LAAWPDPAT----TPQV 839 YW RH R+ V FA V L LEIGPR VLTA + + +PA TP V Sbjct: 812 DYWVRHVREAVRFADGVAALRAAGVDTFLEIGPRSVLTAMTRDVLSGREPADADDDTPVV 871 Query: 840 -LASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDN 897 + +LR + R + A++ + G D+ A + A + LPTY F+ +++W Sbjct: 872 AVPALRADRPESRALLAALSELHVNGTPVDWAALYAGTGATPVALPTYAFQRQRYW---- 927 Query: 898 RAIDRDTQTASAGSVTPHRTQAV--RLLEDGQIEELAALI--DGETVDEQTLRVLNKLAA 953 ++ G V+P +E + LAA I DG +D + + Sbjct: 928 ---PEQMPASATGPVSPDVVDVEFWSAVERSDVAALAAQIGVDGAALDVLAPALPVLSSW 984 Query: 954 RHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGD-DTAAVLEFADALT----- 1007 R + R VD + Y + W W+LV D AA E+A AL Sbjct: 985 RRARLRDAVVDGWS-YRVVWKRTAAPAPVTPSGR-WLLVEPADDAATTEWAGALAGALSA 1042 Query: 1008 AGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHR--- 1064 AGG ++ P ++ D+ T R A A V A G + + LL H Sbjct: 1043 AGGEVSRLAVDPLAERDQV----TSRVAQA-----VQNAPFTGIVS-LLGLLERPHPGRP 1092 Query: 1065 --TLG--GLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVP-EQSCLWGFGRAAALEL 1119 LG L +A + A++ +P+W++TR DTD V Q LWG R A LE Sbjct: 1093 AVPLGTAATMTLVQALHAADVTAPLWMLTRGAVGTGDTDPVRSVAQGGLWGLARVAGLEH 1152 Query: 1120 PHIWGGLADLSGADT--EWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPL 1177 P +WGGL DL A +W + +T EDQ+A+R V+ RLVR T Sbjct: 1153 PQLWGGLVDLPDAPGRGDWDHAVGVLTGGGP-EDQVAVRPSGVFVRRLVRATPAAVGAVD 1211 Query: 1178 PVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDV 1237 + T LVTGG GA+G VA + A++GA H+VLTSRR V Sbjct: 1212 RWQPSGTVLVTGGTGALGAHVARWAAANGAEHLVLTSRRGEHAPGAAELRDELTGLGARV 1271 Query: 1238 RVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWG 1297 ++ AD+AD V L+ V A+ PL +VHAAG T L D A + V GK+ G Sbjct: 1272 TLVAADMADRARVEALLRDVDADPAPLTAVVHAAGVGQLTMLVDTDLAGLAGVLDGKIAG 1331 Query: 1298 AWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSV 1357 A HL E L D LD FV SSIA +WG GQ AY A NAFLD LA R R RG+ A +V Sbjct: 1332 AVHLDELLGD--RPLDAFVLFSSIAGIWGSGGQAAYAAGNAFLDALAERRRARGLAATAV 1389 Query: 1358 NFGPWA-AGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPL 1415 +GPWA GMA E + L +RG+ +SPA+A+ + V V V VA +DWS F P Sbjct: 1390 AWGPWAEGGMASGEGQELLARRGLSPMSPAQAVYALRSAVGRAVPSVTVADVDWSLFTPA 1449 Query: 1416 YQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAV 1475 + A R L ++ +E L + L P ++ +T+ +R Sbjct: 1450 FAAARARPLLDDV-AEARDALRVVDAEPEDTAGGGLRQHLLTLPRAEQDRHLTDLVRTHT 1508 Query: 1476 AEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADY 1534 A V D ++ F +LG DSL AVELR R+ G +P TLV D+P + AD+ Sbjct: 1509 AAVLGHSGTDLVKAGRAFKELGFDSLTAVELRNRLGAATGLTLPTTLVFDYPNPAALADH 1568 Query: 1535 LLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIRE 1593 L V L L E V DPI +V +SCR+PG +P+ W+L+A G D I Sbjct: 1569 LSV-TLRLHEVETVTAWGPAGPVDGDPIVIVGMSCRYPGGVANPDDLWDLVATGRDGISG 1627 Query: 1594 VPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLML 1652 P+DR WD+ D D ++TR P FFGISPREAV ++PQQRL+L Sbjct: 1628 FPDDRHWDMGRLLAVDADGQPVSHTREGGFVDGATTFDPGFFGISPREAVAMDPQQRLLL 1687 Query: 1653 ETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISG 1712 E WE +E+AG P +LRGSRTGVF G + + Y + ++ ++ + +TG A + ISG Sbjct: 1688 EASWEAMEQAGIDPDELRGSRTGVFVGASPSGYG---TTDTPAELAGYQLTGGAHSVISG 1744 Query: 1713 RVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASR 1772 RV++ G EGPAV VDTACSS+LVAVH A QAL+ G+CD+ALAGGV V+++P V SR Sbjct: 1745 RVSYTFGLEGPAVTVDTACSSSLVAVHLAAQALRGGECDMALAGGVTVMVTPGAFVEFSR 1804 Query: 1773 ARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASS 1832 L+P GRCK+F A ADG SEG GVL+++RLSDA R G +V AV+ S+VNQDGAS+ Sbjct: 1805 QGGLAPDGRCKSFAADADGTGWSEGVGVLLVQRLSDARRQGRQVLAVLAGSAVNQDGASN 1864 Query: 1833 GLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXX 1892 GLT PNG AQQR+I LA A L+ ADVD +EAHGTGT LGDPIE Q Sbjct: 1865 GLTAPNGPAQQRVIRQALANARLTTADVDAVEAHGTGTTLGDPIEAQALLATYGQGRPAD 1924 Query: 1893 XPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVID 1952 PLL+GS+K+NIGH+++A+G AG+IK+V ++++G+LP++LH + P+PH+ W + V ++ Sbjct: 1925 RPLLLGSIKSNIGHSQAAAGVAGMIKMVQAMRYGLLPRTLHLDEPTPHVDWSSGAVSLLT 1984 Query: 1953 EPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEE--APPQLHXXXXXXXXXXXXXXXGTDDS 2010 E PW R RRA VSSFG +GTN H+++E+ AP T D Sbjct: 1985 EARPWPAVDRPRRAAVSSFGISGTNVHLILEQPSAPTDADEPADGDEPV-------TGDE 2037 Query: 2011 PQ------VLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALV 2064 P L LSAR L A R+ WL T DV ++ RS E+RA + Sbjct: 2038 PSRPPTVLPLLLSARDAAGLSAQAGRWAQWLGGTEAPRPLDVAWSSVASRSVLEHRAVVS 2097 Query: 2065 VDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFA 2124 S PAGV+ G R A LF+GQG+Q GM REL+ PVFA Sbjct: 2098 GASRDELLAGLEAVSAGELPAGVLTGPGGQRGQLALLFSGQGAQRAGMGRELYGVFPVFA 2157 Query: 2125 QTVRQCAEAVADMLPRPLLDVLFAT-DRETADLLQHTSFAQPALFAVEMGLARLWQSWAI 2183 + + + +LPRPL +VLFA+ + A LL T F Q LFAVE+ L RL +S+ + Sbjct: 2158 AALDEVCGQLDPLLPRPLREVLFASANSAEAGLLDQTVFTQAGLFAVEVALFRLVESFGV 2217 Query: 2184 EPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFAD-AEHVEQ 2242 PD++ GHS+G+ AA VAGV SL D L+A RGR+ +LP GG M+AV AD A E Sbjct: 2218 VPDMLAGHSIGEVTAAHVAGVLSLADACALVAARGRLMQALPTGGGMLAVAADEAAVAES 2277 Query: 2243 VAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVL 2301 VAG RV + A NGP V+SG E L E+ + D G+R L SHAFHS L+ P+L Sbjct: 2278 VAGLTDRVGIAAVNGPAAVVVSGAVEALAEVERVWRDRGVRTRRLTLSHAFHSPLMAPML 2337 Query: 2302 DXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALG 2361 D P LP+V N TGA L G +YW RH R+ V++A+ V V A G Sbjct: 2338 DEFRTVLGGLAFAAPLLPVVSNVTGA-LVGDEICTPEYWVRHVREAVRYADGVAAVRAAG 2396 Query: 2362 CSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF 2421 +E+GPQ VLT + + A AVA R+ ++ + + ALA +V G + Sbjct: 2397 VDTFLEVGPQSVLTAMNADLLADDEAV-LAVAVQRRDRSEAQALLHALAELHVHGVPVTW 2455 Query: 2422 AAVHRQP-RRPVELPTYPFQRRRFW--PKASSIAVDG---GTAASGILGSGKDLASGD-T 2474 + + R V+LPTY FQR R+W P S V G G A +LG+ +A D Sbjct: 2456 QSWFAETGARRVDLPTYAFQRERYWLPPTGRSADVSGAGLGVARHPLLGAAVSVAGEDMV 2515 Query: 2475 IYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEP-IILP 2530 + T RLSV + PWLADHV+ G VVVPG + + A VG +R++++ P ++L Sbjct: 2516 VLTGRLSVSTHPWLADHVVSGAVVVPGTALVDLVVRAGDEVGA-SRVRELTVLAPLVLLA 2574 Query: 2531 EKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSD 2590 VQ+ + P DG S +HS+ + + W+ +A+G V +D Sbjct: 2575 TGGGVRVQVRVGPVDGTGSRSVTVHSQSEDDPESGWTRHADGLVGAPTADEPTLGAWPPP 2634 Query: 2591 PVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQL 2650 EV + T A+ LA+GP + G L+ W DGE ++ + E A Sbjct: 2635 GASEV-------DVTGWYATVAEHGLAYGPVFRG-LRRAWTADGEVFAEVALADEFAGDP 2686 Query: 2651 GSEPMHPVLMD 2661 +HP L+D Sbjct: 2687 AGFGVHPALLD 2697 Score = 1519 bits (3932), Expect = 0.0 Identities = 1003/2501 (40%), Positives = 1323/2501 (52%), Gaps = 129/2501 (5%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFD 58 +V + PI AI+G A R+PG S +E W LL G + IS+ P DR WD+E FD Sbjct: 6834 VVGTDEPI------AIVGMACRYPGGVESPDELWGLLAGGGDGISEFPADRGWDLESLFD 6887 Query: 59 PDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAP 118 PDP+ G TR GF+ FD FFG+S RE MDPQ R+L+E +W + E +G+ P Sbjct: 6888 PDPNRSGTSYTRHGGFLYGAAEFDPGFFGISPREALAMDPQQRLLLEASWESFESAGLDP 6947 Query: 119 TSLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAV 178 L S TGVF G+ HDY D T E+E Y+ GTS + +GR++Y GL+GPAV Sbjct: 6948 QRLRGSRTGVFAGVMYHDYASRLMDLPT--EVEGYVGTGTSGSVLSGRVAYTFGLEGPAV 7005 Query: 179 AVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTF 238 VDTACSSSLVA+H A QALR ECDLALAGG V+ TP T I FS L+ DGRCK+F Sbjct: 7006 TVDTACSSSLVALHLAAQALRSGECDLALAGGVTVMATPGTFIEFSRQRGLSQDGRCKSF 7065 Query: 239 DAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRV 298 A+ADG EG GV++V+RL DA R+G +I AV+RG+A+NQDGAS GLT PNG +QQRV Sbjct: 7066 AASADGTGWSEGVGVLLVQRLSDAQREGRKIYAVVRGTAVNQDGASNGLTAPNGPSQQRV 7125 Query: 299 IADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIG 358 I AL A L P+DV +EAHGTGT+LGDPIEAQA G R EPL +GS K+NIG Sbjct: 7126 IRQALASARLSPSDVDVVEAHGTGTTLGDPIEAQAVLATYGQDRQGREPLWLGSVKSNIG 7185 Query: 359 HLEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRI 418 H + + + +P L+ + PSPH+ W + + E PW +PR Sbjct: 7186 HTQAAAGVAGVIKMVMAMRHGLVPATLHVDEPSPHVDWSAGAVALATEPTPWPAVDRPRR 7245 Query: 419 AGVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRD 478 A VSSFG +GTNAHVI+E+ PA + P VL LSAR+ AL AG + Sbjct: 7246 AAVSSFGISGTNAHVIIEQPPAETIEGEIVARDLPPVVPVL-LSARSDAALAGQAGRWAR 7304 Query: 479 WLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESH 538 WL A R DV+ ++ T R LEQRA VV + L AL P+ +V G + Sbjct: 7305 WLAADEAPRPLDVAWSSVTTRPALEQRAVAVVADGNDLLTALRALDASEPSGTVVTGSTA 7364 Query: 539 EAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELD 598 + A LF+GQG+Q GM REL+ PVFA + + + +L +PL +V+F + Sbjct: 7365 VRGQLALLFSGQGAQRAGMGRELYAGFPVFATALDEVCGHLDPLLPRPLREVLFASS--- 7421 Query: 599 GDTESPLR-HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVED 657 G E+ L T + Q LFAVE+ L RL +S+G PDVV GHS+G+ +AA VAGV + D Sbjct: 7422 GSAEAGLLDQTVFTQAGLFAVEVALFRLVESFGVVPDVVAGHSIGEVTAAHVAGVLSLAD 7481 Query: 658 GARLIAERGRLFGSLPAGGRMAAVFTAPERA--ERLTDEYPSLSVAAYNGANTVL-SGPA 714 +L+A RGRL +LP GG M AV A E A E + VAA NG V+ SG Sbjct: 7482 ACQLVAARGRLMQALPTGGGMLAV-AADEAAVVESIAGLADRAGVAAVNGPTAVVVSGAV 7540 Query: 715 KDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTG 774 + L+ GVR L SHAFHS L++P+LD+F + L + P ++ N TG Sbjct: 7541 EALDEVERAWRDRGVRTRRLTVSHAFHSPLMEPMLDEFRTILHGLTFATPLLPVVSNVTG 7600 Query: 775 SALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPA 834 + YW RH R V FA + L LE+GP+ VLTA A P Sbjct: 7601 ALADADEIRTADYWVRHVRDAVRFADGITALKAAGIDTFLEVGPQSVLTAMAADVLPGDD 7660 Query: 835 TTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFW 893 V R H + A+A + G +++ F AR++DLPTY F+H+++W Sbjct: 7661 AVLAVAVQRRDRPEAHA-LLHALAELHVHGVPVTWQSWFADTGARRVDLPTYAFQHQRYW 7719 Query: 894 FSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAA 953 Q A G T+ +E G + LAA + G+T D L L A Sbjct: 7720 PEGTPT----RQAAPEGG----DTEFWAAVERGDLAALAAELGGDTEDLDALGPALPLLA 7771 Query: 954 RHNQQRSTHVDPDA-RYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHR 1012 R Q RS D Y I W+ W++V D+ A A LT G R Sbjct: 7772 RWRQHRSRDTALDGWSYRIGWEPVRPAPATRLSGR-WLVVTVDSGADAGVAKTLTQAGAR 7830 Query: 1013 HQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGG---- 1068 D + TL A GE + +GDG A + L R Q R L Sbjct: 7831 ----------VDTLTVSSTLARAELGER--LGRISGDGWAGVLCVLPR-QDRPLADTPAV 7877 Query: 1069 ------LRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCL-WGFGRAAALELPH 1121 L L RA D L +W ++R VT + + L WG GR ALE P Sbjct: 7878 PAGTAVLLTLVRALTDTGLAGRVWALSRTAMPVTAGERAGDVWAALAWGLGRVVALEQPD 7937 Query: 1122 IWGGLADLSGADTEWPR--LIARITSPRDGE-DQIALRGDAVYAPRLVRRTGEPSDTPLP 1178 WGGL DL R L+A + DG DQ+A+R + ++ RLV P+ P Sbjct: 7938 RWGGLVDLPDRADRGARAGLVAVLA---DGTLDQVAVRRNGLFGRRLV-----PAAPPAG 7989 Query: 1179 V--REDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACD 1236 R T LVTGG GA+G VA +L ++GA VVL SRR P Sbjct: 7990 AGWRPAGTVLVTGGTGALGRHVARWLLANGAAEVVLASRRGPAAPGAAELVAELGA---- 8045 Query: 1237 VRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSG-LDDAEVDRVFAGKV 1295 VRV+ DV D V L++ LP L +VH AG G T + + D E+ AGKV Sbjct: 8046 VRVVACDVTDRAAVEALVSG----LPELTAVVHTAGASGGTAAAHEVTDGELSETLAGKV 8101 Query: 1296 WGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAV 1355 GA HL A DLD FV SS+A VWGG GQ Y A NA LD L R +G+ A Sbjct: 8102 LGALHLDTACRG--RDLDAFVVFSSVAGVWGGGGQAGYAAGNALLDTLVAARRAKGLPAT 8159 Query: 1356 SVNFGPWAA-GMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQG-VVAKIDWSRFL 1413 ++ +GPWA GMA E+ L +RG L+P A+A + V P V+ +DWSRF+ Sbjct: 8160 ALAYGPWAEDGMAAGETADGLRRRGFSPLAPDAAVAALGRWVNAPEAAPVIVDVDWSRFV 8219 Query: 1414 PLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR- 1472 + A + + L +L P +++L+ + +R Sbjct: 8220 TAFTAARPSHLFDRVAPAVAGEPQRPENTAATDG---LRNRLATLPATGQEALLVDLVRA 8276 Query: 1473 NAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAA 1532 A A + D++ F +LG DSL AV+LR R+ + G +P T+V DHP ++ A Sbjct: 8277 EAAAVLGHPTTDQVPAGRAFRELGFDSLAAVQLRDRLGRVTGLTLPSTVVFDHPSAAELA 8336 Query: 1533 DYLLVEVLGLGEQTNVRQASTVTAR--TDDPIAVVAVSCRFPGA-PDPESFWELLAGGVD 1589 +L E++ +G AR D+PIA+V+++CRFPG P+ W LLA GVD Sbjct: 8337 RFLRTEIV-VGADGGPAAGGATAARPAADEPIAIVSMACRFPGGVSSPQELWRLLADGVD 8395 Query: 1590 AIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQ 1648 A+ +P DR WD+D +D DP+ G +YTR FFGI+PREA+ ++PQQ Sbjct: 8396 AVTPMPADRGWDLDALFDSDPEQVGTSYTRSGGFLHDVAGFDAAFFGINPREALAMDPQQ 8455 Query: 1649 RLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALN 1708 RL+L T WE E AG P +RGS TGVF G +YA LL ++E + TGN + Sbjct: 8456 RLLLHTTWEAFEHAGIDPHRVRGSATGVFMGTNGQDYATLLLGARA-QVEGYQATGNGAS 8514 Query: 1709 AISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVV 1768 +SGR+A++ G GPAV VDTACSS+LVA+H A QAL+SG+CDLALAGGV V+ +P + Sbjct: 8515 VVSGRLAYSFGLHGPAVTVDTACSSSLVALHLATQALRSGECDLALAGGVTVMSTPGAFL 8574 Query: 1769 AASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQD 1828 SR R L+ GR K F +ADG EG GVL+L+RLSDA RDG+R+ AV+ S+VN D Sbjct: 8575 EFSRQRGLAADGRVKAFAEAADGTGWGEGVGVLLLQRLSDAQRDGNRILAVVRGSAVNSD 8634 Query: 1829 GASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXX 1888 GAS+GLT PNG AQQR+I L AGL+ ADVD +EAHGTGT LGDPIE Q Sbjct: 8635 GASNGLTAPNGPAQQRVIRHALDNAGLTPADVDVVEAHGTGTTLGDPIEAQALLATYGRD 8694 Query: 1889 XXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPV 1948 PL +GSVK+NIGHT++A+GAA LIK+VL+LQH VLP++LH + P+PH+ W + + Sbjct: 8695 RTADRPLWLGSVKSNIGHTQAAAGAASLIKMVLALQHEVLPKTLHVDAPTPHVDWSSGTL 8754 Query: 1949 RVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTD 2008 ++ E PW T RRAGVSSFG +GTNAHV++E+AP + Sbjct: 8755 ALLTEARPWTTTEGPRRAGVSSFGISGTNAHVILEQAPDR------------PEPVFPDG 8802 Query: 2009 DSPQVL---ALSARSPEALVELARRYDDWLSATPGLDIAD-VCHTAGVGRSHFEYRAALV 2064 D P + +SA AL E A R D A G D AD V GR+H RA +V Sbjct: 8803 DRPAAILPWPVSAADLPALREQAGRLAD--RAATGDDPADLVAWALADGRAHLGRRATVV 8860 Query: 2065 -VDSVXXXXXXXXXXXXXXTPAGVV---RGEHVHRPTTAWLFTGQGSQYPGMARELFDTQ 2120 D PA V RG + A F+GQG+Q PG R L+DT Sbjct: 8861 AADRATRTAALRALAAGEEHPAVVTARRRGGGL-----AVQFSGQGAQRPGAGRRLYDTF 8915 Query: 2121 PVFAQTVRQCAEAVADMLPRPLLDVLFATDRET-ADLLQHTSFAQPALFAVEMGLARLWQ 2179 PVFA + + + LP+PL VLFA + A LL T F Q LFA+E+ L RL + Sbjct: 8916 PVFAAALDEVCAVLDHQLPQPLKPVLFAAEGSAEATLLDETVFTQAGLFALEVALFRLVE 8975 Query: 2180 SWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFAD-AE 2238 S+ + P V GHS+G+ AA VAGV SL D A L+A RGR+ +LP GG M+AV AD A Sbjct: 8976 SFGVVPGHVAGHSIGEITAAHVAGVLSLADAATLVAARGRLMQALPAGGGMLAVAADEAA 9035 Query: 2239 HVEQVAGEFPRVSVGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELL 2297 VE +AG RV V A NGP VL+G + L+ + + + G+R L SHAFHS L+ Sbjct: 9036 VVESLAGLGDRVGVAAVNGPTAVVLAGALDALDGLERLWRERGVRTRRLRVSHAFHSPLM 9095 Query: 2298 DPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTV 2357 +P+L P LP+V N TG + YW RH R+ V++A+ + + Sbjct: 9096 EPMLTDFRAVLDGLTFAAPLLPIVSNLTGRLAEPDEIRTPGYWVRHVREAVRYADGIAAL 9155 Query: 2358 AALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGH 2417 G +E+GPQ VLT + P+ AVA+LR G + + ALA + G Sbjct: 9156 RDAGVDTFLELGPQAVLTAMTAGLLPD-ADDGTAVAALRAGADEPAALLAALAVVHGTGR 9214 Query: 2418 RPDFAAV------HRQPRRPV-ELPTYPFQRRRFWPKASSI 2451 D+AAV R RR + ELPTY F+ +R+WP ++ Sbjct: 9215 DVDWAAVLAALAGPRPDRRLLPELPTYAFRPQRYWPTLDTL 9255 Score = 953 bits (2464), Expect = 0.0 Identities = 724/2112 (34%), Positives = 1019/2112 (48%), Gaps = 149/2112 (7%) Query: 916 RTQAVRLLEDGQIEELAAL----IDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEI 971 RT VRL G L A + +VD TLR + LAA ++ + +E+ Sbjct: 2732 RTLRVRLTASGSSVRLVATDETGVPVVSVDSLTLREMTGLAAAPDEAYRS------LFEV 2785 Query: 972 RWDXXXXXXXXXXXXXDWILVGD-------DTAAVLEFADALTAG--GHRHQIVALPGSD 1022 W W+++G A AD TA G + LP + Sbjct: 2786 SWQPEQIAAPDGAYG--WVVLGGRPLDGAPQLPAYAGVADLTTAATDGTAPAALLLPVTP 2843 Query: 1023 ADE-AQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAEL 1081 A A + D +R+ +A L VV AAAP+ D RL A Sbjct: 2844 APSGADVPDAVRSVTADVLGVVQAWL---AAAPLAD------------SRLVVVTRGA-- 2886 Query: 1082 RSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIA 1141 + T RVTD + +WG R+A E P LADL L+A Sbjct: 2887 -----VATGADDRVTDL-----AGAAVWGLLRSAQSEHPGRIV-LADLEPGTDLDADLLA 2935 Query: 1142 RITSPRDGE---DQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEV 1198 + + DG Q+A+R Y PRLVR TG + TP + T LVTGG G++G V Sbjct: 2936 LLAAVADGPALGGQVAVRSGTAYLPRLVRATGA-ARTPAALGGG-TVLVTGGTGSLGALV 2993 Query: 1199 AGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTV 1257 + +L + +G +VL SR+ P RV+ DV D V L+ ++ Sbjct: 2994 SEHLVTAYGVRSLVLVSRQGPAAPGADELVRRLAALGATARVVATDVTDRERVGELVRSI 3053 Query: 1258 AAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVS 1317 A+ LAG+VH AG + +SG+ + V A KV W L EA +L DLD FV Sbjct: 3054 TAD-DRLAGVVHTAGVLDDGIVSGITADRLADVLAPKVTAGWWLHEATAEL--DLDLFVL 3110 Query: 1318 TSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW-----AAGMADAESR 1372 SS+A V G GQ AY A NAFLD LA +RG+ AVS+ +G W AA + DA+ R Sbjct: 3111 FSSVAGVLGSPGQAAYAAGNAFLDALAVLRAQRGLPAVSLAWGMWDTDGMAASINDAD-R 3169 Query: 1373 ARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESEL 1432 AR+ + G L P A G+ A G A + LP A R + + Sbjct: 3170 ARVTRAG---LVPMTAPVGLGLWDAALTHGGAALVPAVVDLP----AMRAQTAAGRVPVM 3222 Query: 1433 XXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAG 1491 ++L Q+ ++ + +R +A+V A+ + + Sbjct: 3223 LRGLVGPAAKRRRSGTGAWADRLAGLDPQEARTQVALLVRGMIAQVLGHGGAEAVPADRA 3282 Query: 1492 FFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQA 1551 F +LG DSL AVELR RI G + TLV D+P +++L ++ G Q +Q Sbjct: 3283 FRELGFDSLTAVELRNRINSASGLRLTSTLVFDYPTPGALSEHLYEQLSG---QVAAQQQ 3339 Query: 1552 STVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDP 1609 + D+PIA+V ++CR+PG +P+ W+L+A G D I E P DR WD+D + PDP Sbjct: 3340 AVRATTVDEPIAIVGMACRYPGGVTNPQQLWDLVAAGADGIGEFPTDRGWDLDRLFHPDP 3399 Query: 1610 DTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDL 1669 D PG +YTR P+FFGISPREA+ ++PQQRL+LE WE E AG PS L Sbjct: 3400 DNPGTSYTRHGGFLYGAAEFDPDFFGISPREAIAMDPQQRLLLEASWETFESAGLDPSRL 3459 Query: 1670 RGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDT 1729 RGSRTGVF G+ ++YA + + + + + TG + + +SGRVA+ G EGPAV VDT Sbjct: 3460 RGSRTGVFAGLMYHDYASGVQ-DLPEGVGGYLGTGTSGSVLSGRVAYTFGLEGPAVTVDT 3518 Query: 1730 ACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASA 1789 ACSS+LVA+H A QAL+ G+CDLALAGGV V+ +P T + SR R LS GRCK+F ASA Sbjct: 3519 ACSSSLVALHLAVQALRGGECDLALAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASA 3578 Query: 1790 DGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEAT 1849 DG SEG GVL+++RLSDA R+G RV AV+ ++VNQDGAS+GLT PNG +QQR+I Sbjct: 3579 DGTGWSEGVGVLLVERLSDAQRNGHRVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQA 3638 Query: 1850 LARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTES 1909 LA A L+ ADVD +EAHGTGT LGDPIE Q PL +GSVK+NIGHT++ Sbjct: 3639 LANARLTAADVDAVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSVKSNIGHTQA 3698 Query: 1910 ASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVS 1969 A+GAAG+IK++++++HGVLP +LH + PSPHI W A V ++ E W GR RRA +S Sbjct: 3699 AAGAAGIIKMIMAMRHGVLPSTLHVDEPSPHIEWSAGEVSLLTEARDWPAAGRPRRAAIS 3758 Query: 1970 SFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELAR 2029 SFG +GTNAHV++E+ P + P + LSARS A+ A Sbjct: 3759 SFGVSGTNAHVIIEQPPAEAEPTRGEGAPTPT-----AGQLPSPVLLSARSEAAVAAQAE 3813 Query: 2030 RYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVR 2089 R+ W++ L DV ++ V R+ E+RA A VV Sbjct: 3814 RWARWIAGDEELRPLDVGWSSTVSRAVMEHRAVATATDRDELLAGLRALADGEPAATVVT 3873 Query: 2090 GEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFAT 2149 G R A LF+GQG+Q GM REL+ PVFA + + + +LPR L +VLFA+ Sbjct: 3874 GTGATRTQLAVLFSGQGAQRAGMGRELYAGFPVFATALDEVCAQLDPLLPRALREVLFAS 3933 Query: 2150 -DRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLD 2208 +LL T F Q LFAVE+ L RL +S+ + PDVV GHS+G+ AA VAGV SL Sbjct: 3934 AGTAEVELLDQTVFTQAGLFAVEVALFRLVESFGVVPDVVAGHSIGEVTAAYVAGVLSLA 3993 Query: 2209 DGARLMAERGRMFGSLPEGGRMVAVFAD-AEHVEQVAGEFPRVSVGAYNGP-NTVLSGPG 2266 D L+A RGR+ +LP GG M+AV AD A E +AG R+ + A NGP V+SG Sbjct: 3994 DACALVAARGRLMQALPTGGGMLAVAADEAAVAESLAGMTDRLGIAAVNGPAAVVVSGAV 4053 Query: 2267 EDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTG 2326 E L+E+ + + G+R L SHAFHS L++P+LD P LP+V N TG Sbjct: 4054 EALDEVERVWRERGVRTRRLTVSHAFHSPLMEPMLDEFRAVLAGLTFRAPLLPVVSNLTG 4113 Query: 2327 AVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHM 2386 A+ Q A+YW RH R+ V++A+ + + A G +EIGPQ VLT + E Sbjct: 4114 ALADPQEITRAEYWVRHVREAVRYADGIAALRATGVDTFLEIGPQSVLTAMNADLLAEDA 4173 Query: 2387 AAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQP-RRPVELPTYPFQRRRFW 2445 AVA R+ + + ALA +V G + V+LPTY FQ +R+W Sbjct: 4174 L---AVAVQRRDRPAPQALLHALADLHVHGVPVTWTQWFTDAGAARVDLPTYAFQHQRYW 4230 Query: 2446 -----PKASSIAVDG-GTAASGILGSGKDLASGD-TIYTSRLSVKSQPWLADHVIYGTVV 2498 +A+ ++ G G A +L + +A D + T RLS + WLADHV+ G V+ Sbjct: 4231 LGAGQARAADVSGAGLGVAGHPLLAAAVSVAGADMVVLTGRLSTSTHAWLADHVVSGAVI 4290 Query: 2499 VPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIH 2555 VPGA +A+ A VG +R++++ P++LP+ + VQ+ + AD V +H Sbjct: 4291 VPGAALVELAVRAGDEVGA-SRVRELTVAAPLVLPQAGAVRVQVRVGAADETGVRVVAVH 4349 Query: 2556 SRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLE 2615 S+ G+ ADW +AEG ++ A + + + EV + T A+ Sbjct: 4350 SQSEGDPEADWVRHAEGVLEPASAGEPSLGEWPPVGASEV-------DVAGWYPTLAEHG 4402 Query: 2616 LAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXX 2675 LA+GP + G L+ +W G E ++ + E+A + +HP L+D Sbjct: 4403 LAYGPVFRG-LRRVWTGGDEVFAEVALPDEVATEAARFGVHPALLDAA-----LHPIGLL 4456 Query: 2676 XXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGG 2735 +G +P + V + + AR R L L D G A+ Sbjct: 4457 PGTEGSGGPRVPFAFEGVQV-------YASGARVLRVRLSRTGSAVRLVACDESGAAVVS 4509 Query: 2736 IREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVP 2795 + A RE G A R ++ L W + D + W + G A Sbjct: 4510 VDSL----ALRELTGVTAAGAAARAMFELTWQAEEIAATGD--LSGWALVGSPATA---- 4559 Query: 2796 GCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNL 2855 DL G+V + A AG + P + + Sbjct: 4560 ---------DLPAYGDVEALVAAVDAGRTVAPRALLLP---IDGPERAVPDAVRAATSEV 4607 Query: 2856 LSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRL 2914 L+ V + L +VT V+ + + V D AA+WG R+ +E P L Sbjct: 4608 LATVRSWLAADALAESRLVVVTRGAVSVAADDRVSDLAGAAVWGLLRSAQSEHPG-RIVL 4666 Query: 2915 VDCDGSSEA--VDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGD-FV 2971 D DG +A + P ++AVR G + RL+ + + P GD V Sbjct: 4667 ADVDGDVDAGLLGVLTTVADEPSTHGGQVAVRAGAVFVPRLVRAVAAASVETPVVGDGAV 4726 Query: 2972 LAPTERGAIDNL 2983 L GA+ L Sbjct: 4727 LVTGGTGALGAL 4738 Score = 949 bits (2453), Expect = 0.0 Identities = 760/2125 (35%), Positives = 1015/2125 (47%), Gaps = 184/2125 (8%) Query: 916 RTQAVRLLEDGQIEELAALIDGE----TVDEQTLRVLNKLAARHNQQRSTHVDPDARYEI 971 R VRL G L A + +VD LR L + A R A +E+ Sbjct: 4482 RVLRVRLSRTGSAVRLVACDESGAAVVSVDSLALRELTGVTAAGAAAR-------AMFEL 4534 Query: 972 RWDXXXXXXXXXXXXXDWILVGDDTAAVLEF---ADALTAGGHRHQIVA----LPGSDAD 1024 W W LVG A L +AL A + VA L D Sbjct: 4535 TWQAEEIAATGDLSG--WALVGSPATADLPAYGDVEALVAAVDAGRTVAPRALLLPIDGP 4592 Query: 1025 EAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSP 1084 E + D +RAA++ L A +R L A DA S Sbjct: 4593 ERAVPDAVRAATSEVL------------ATVRSWL----------------AADALAESR 4624 Query: 1085 IWLVTRDGQRVTDTDTVVP-EQSCLWGFGRAAALELPHIWGGLADLSG-ADTEWPRLIAR 1142 + +VTR V D V + +WG R+A E P LAD+ G D ++ Sbjct: 4625 LVVVTRGAVSVAADDRVSDLAGAAVWGLLRSAQSEHPGRIV-LADVDGDVDAGLLGVLTT 4683 Query: 1143 ITS-PRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGY 1201 + P Q+A+R AV+ PRLVR S PV D LVTGG GA+G VA + Sbjct: 4684 VADEPSTHGGQVAVRAGAVFVPRLVRAVAAAS-VETPVVGDGAVLVTGGTGALGALVAEH 4742 Query: 1202 LAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAE 1260 L S HG +VL SRR VRV+ DV D V L+ VAA Sbjct: 4743 LVSAHGVRSLVLVSRRGAEAAGAGELSERLSALGASVRVVACDVTDRDQVFGLVAEVAAG 4802 Query: 1261 LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS 1320 LAG+VH AG + + GL + V A KV W L EA L LD FV SS Sbjct: 4803 -GRLAGVVHTAGVLDDGVVEGLTAERLVGVLAPKVSAGWLLHEATASLA--LDLFVVFSS 4859 Query: 1321 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW-AAGMA---DAESRARLE 1376 +A V G GQ+AY A NAFLDGLA R+ G+ AVS+ +G W AGMA D RAR Sbjct: 4860 VAGVLGSPGQSAYAAGNAFLDGLAVYRRQLGLPAVSLAWGMWDTAGMAASIDEADRARSA 4919 Query: 1377 QRGVRTLSPAEALAGM----ADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESEL 1432 + G L+P A G+ A +VA V A ID +P + A + + L Sbjct: 4920 RAG---LTPMSAEIGLELFDAALVAERPALVPAVID----VPAMRAA---LGAGPVPAVL 4969 Query: 1433 XXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAG 1491 QL + ++ I +R VA+V A+ + + Sbjct: 4970 RTLIGSTAARRRAARSGDWANQLAGLAPDEARAQIDVLVRGLVAQVLGHGGAEAVPADRA 5029 Query: 1492 FFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQA 1551 F +LG DSL AV+LR R+ G + TLV D+P + AD+L +V G Q RQ Sbjct: 5030 FRELGFDSLTAVDLRNRLNAATGLRLASTLVFDYPTPAVLADHLHEQVSG---QITARQT 5086 Query: 1552 STVTARTDDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDP 1609 + +TA TD+PIA+V ++CR+PG D P+ W LLAGG D I E P DR WD++ +DPDP Sbjct: 5087 AVLTAGTDEPIAIVGMACRYPGGVDGPDQLWALLAGGGDGISEFPTDRGWDLESLFDPDP 5146 Query: 1610 DTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDL 1669 + G +YTR P FFGISPREA+ ++PQQRL+LE WE E AG P L Sbjct: 5147 EHSGTSYTRHGGFLYGAAEFDPGFFGISPREALAMDPQQRLLLEASWESFESAGLDPQRL 5206 Query: 1670 RGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDT 1729 RGSRTGVF GV ++YA L D E TG + + +SGRVA+ G EGPAV VDT Sbjct: 5207 RGSRTGVFAGVMYHDYASRLMDLPPDA-EGFVGTGTSGSVLSGRVAYTFGLEGPAVTVDT 5265 Query: 1730 ACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASA 1789 ACSS+LVA+H A QAL+SG+CDLALAGGV V+ +P T + SR R LS GRCK+F ASA Sbjct: 5266 ACSSSLVALHLAAQALRSGECDLALAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASA 5325 Query: 1790 DGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEAT 1849 DG SEG GVL+++RLSDA R+G RV AV+ S+VNQDGAS+GLT PNG +QQR+I Sbjct: 5326 DGTGWSEGVGVLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQA 5385 Query: 1850 LARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTES 1909 LA A L+ ADVD +EAHGTGT LGDPIE Q PLL+GSVK+NIGHT++ Sbjct: 5386 LANARLTPADVDAVEAHGTGTTLGDPIEAQALLATYGQERPQDRPLLLGSVKSNIGHTQA 5445 Query: 1910 ASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVS 1969 A+G AG+IK+VL+++HGV+P +LH + SPH+ W A V + EP PW R RRA VS Sbjct: 5446 AAGVAGVIKMVLAMRHGVVPATLHVDEASPHVDWSAGAVALATEPTPWPRVDRPRRAAVS 5505 Query: 1970 SFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV--LALSARSPEALVEL 2027 SFG +GTNAHV++E+ P + D P V + LSAR AL Sbjct: 5506 SFGISGTNAHVIIEQPPAE-----------TIEGEVVAGDVPPVVPVLLSARDAAALSAQ 5554 Query: 2028 ARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGV 2087 A R+ WL+A DV ++ R E+RA + V Sbjct: 5555 AGRWARWLTADEAPRPLDVAWSSVTTRPALEHRAVVTAADRDDLVAALTALADGDPTGTV 5614 Query: 2088 VRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLF 2147 V G R A LF+GQG+Q GM REL PVFA + + + +LPRPL +VLF Sbjct: 5615 VSGATGQRGRLALLFSGQGAQRAGMGRELSAGFPVFAAALDEVCGHLDPLLPRPLREVLF 5674 Query: 2148 AT-DRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFS 2206 A+ A+LL T F Q LFAVE+ L RL +S+ I PD++ GHS+G+ AA VAGV S Sbjct: 5675 ASAGSAEAELLDQTVFTQAGLFAVEVALFRLVESFGIVPDMLAGHSIGEVTAAYVAGVLS 5734 Query: 2207 LDDGARLMAERGRMFGSLPEGGRMVAVFAD-AEHVEQVAGEFPRVSVGAYNGPN-TVLSG 2264 L D L+A RGR+ +LP GG M+AV AD A VE +AG R V A NGP V+SG Sbjct: 5735 LADACALVAARGRLMQALPTGGGMLAVAADEAAVVESIAGLADRAGVAAVNGPTAVVVSG 5794 Query: 2265 PGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNR 2324 E L+E+ + D G+R L SHAFHS L++P+LD P LP+V N Sbjct: 5795 AVEALDEVERHWRDRGVRTRRLMVSHAFHSPLMEPMLDEFRTVLDGLTFSAPLLPVVSNV 5854 Query: 2325 TGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPE 2384 TGA L G A YW RH R V+FA+ + + A G +E+GPQ VLT A V P Sbjct: 5855 TGA-LAGDEIRTADYWVRHVRDAVRFADGITALRAAGIDTFLEVGPQSVLTAMAADVLPG 5913 Query: 2385 HMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQP-RRPVELPTYPFQRRR 2443 A AVA R+ + + ALA +V G + + R V+LPTY FQ +R Sbjct: 5914 DDAV-LAVAVQRRDRPEAHALLHALAELHVHGVPVTWQSWFADTGARRVDLPTYAFQHQR 5972 Query: 2444 FWPKASSIAVDGGTAASG-------ILGSGKDLASGD-TIYTSRLSVKSQPWLADHVIYG 2495 +WP A A G + +G +LG+ DLA D + T RLS+ + PWLADH + G Sbjct: 5973 YWPTAGR-ARTGDVSGAGLGRTGHPLLGATVDLAGDDEMVLTGRLSLATHPWLADHTVSG 6031 Query: 2496 TVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSF 2552 +VPG +A+ A VG +RL+++ P+ LP +Q+ + ++ Sbjct: 6032 LTLVPGTALVELAVRAGDEVGL-SRLRELTMATPLALPGTGGVRIQVRVSTSESPQ-RPV 6089 Query: 2553 QIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFA 2612 ++SRP + A W+ +AEG ++ +D + DPV + + T A Sbjct: 6090 AVYSRPDDDPEAGWTRHAEGVLEPFTAD-------EPDPVTWPPAGAAEVDLASWYPTLA 6142 Query: 2613 DLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXX 2672 + L +GP + G L+ W G E ++++ + E G +HP L+D Sbjct: 6143 EHGLTYGPAFQG-LRRAWTGGDEVYAEVVLPDDATEAAGF-GVHPALLD----------- 6189 Query: 2673 XXXXXEQGVNDLFLPLRYGQVTLAEKMPRRF-----------YCRARWHRSALDSETQVF 2721 ++ + L L G+ + ++P F R R R + Sbjct: 6190 ------AALHPIGL-LLVGEESGGPRVPFAFEGVQVHASGAGALRVRLTRDGSGLRLAAY 6242 Query: 2722 ELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGT 2781 + + +RE T AP G ATR L+ L W V P A + G Sbjct: 6243 DEVGAPVVSVDSLALRELTGVAAP---------GVATRSLFELRWPAVEAAP-AGELSGW 6292 Query: 2782 WLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXX 2841 L+ G EL A P+ T V A AG V P Sbjct: 6293 ALVTGGRELPA------PVGMPTYPDV---------ATAAGEESVPRTLLLP--VFPAPG 6335 Query: 2842 XXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPV-DPVQAALWGFG 2900 +++L+ V + L +VT V+ + V D AA+WG Sbjct: 6336 SATAESVRAVTSDVLATVQSWLAADALADSRLVVVTRGAVSVGDDDRVTDLAGAAVWGLL 6395 Query: 2901 RTTINEEPALHCRLVDCDGSSEA--VDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWAR 2958 R+ +E P L D DG +A + P ++AVR G + + RL+ Sbjct: 6396 RSAQSEHPG-RIVLADVDGDPDAALMALLDGVLREPTATGGQLAVRGGAVHSPRLVRAGI 6454 Query: 2959 SGHLTLPRGGDFVLAPTERGAIDNL 2983 + T G VL GA+ L Sbjct: 6455 TAAETPAVGDGAVLVTGGTGALGAL 6479 Score = 885 bits (2287), Expect = 0.0 Identities = 619/1567 (39%), Positives = 821/1567 (52%), Gaps = 91/1567 (5%) Query: 920 VRLLEDGQIEELAALIDGE----TVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRWDX 975 VRL DG LAA + +VD LR L +AA RS +E+RW Sbjct: 6228 VRLTRDGSGLRLAAYDEVGAPVVSVDSLALRELTGVAAPGVATRSL-------FELRWPA 6280 Query: 976 XXXXXXXXXXXXDWILVGDDTAAVL---EFADALTAGGHRH--QIVALPGSDADEAQLVD 1030 + G + A + + D TA G + + LP A + + Sbjct: 6281 VEAAPAGELSGWALVTGGRELPAPVGMPTYPDVATAAGEESVPRTLLLPVFPAPGSATAE 6340 Query: 1031 TLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTR 1090 ++RA ++ D+L L A DA S + +VTR Sbjct: 6341 SVRAVTS-------------------DVLATVQSWL---------AADALADSRLVVVTR 6372 Query: 1091 DGQRVTDTDTVVP-EQSCLWGFGRAAALELPHIWGGLADLSG-ADTEWPRLIARIT-SPR 1147 V D D V + +WG R+A E P LAD+ G D L+ + P Sbjct: 6373 GAVSVGDDDRVTDLAGAAVWGLLRSAQSEHPGRIV-LADVDGDPDAALMALLDGVLREPT 6431 Query: 1148 DGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLAS-HG 1206 Q+A+RG AV++PRLVR ++TP D LVTGG GA+G VA +L S HG Sbjct: 6432 ATGGQLAVRGGAVHSPRLVRAGITAAETPAV--GDGAVLVTGGTGALGALVAEHLVSVHG 6489 Query: 1207 AGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAG 1266 +VL SRR P VRV+ DV D V L+ VAAE LAG Sbjct: 6490 VRSLVLVSRRGPEAAGAGELSERLSALGASVRVVACDVTDRDQVFGLVAEVAAE-GRLAG 6548 Query: 1267 IVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWG 1326 +VH AG + + GL + V A KV W L EA L DLD FV SS+A V G Sbjct: 6549 VVHTAGVLDDGVVEGLTAERLAGVLAPKVSAGWFLHEATASL--DLDLFVVFSSVAGVLG 6606 Query: 1327 GFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW-AAGMA---DAESRARLEQRGVRT 1382 GQ+AY A NAFLDGLA R+ G+ AVS+ +G W AGMA D RAR + G+ Sbjct: 6607 SPGQSAYAAGNAFLDGLAVHRRQLGLPAVSLAWGMWDTAGMAASIDEADRARSARAGLTP 6666 Query: 1383 LSPAEALAGMADVVAGPVQGVV--AKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXX 1440 +S AE + D G + V+ A ID +P + A + + L Sbjct: 6667 MS-AEIGLELFDAALGADRAVLVPAVID----VPALRAATSGGPVPAVLRTLIGVTGTRR 6721 Query: 1441 XXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDS 1499 ++L + ++ + +R VA+V A+ + + F +LG DS Sbjct: 6722 QAGQGGGGW--ADRLAGLTEDEGRAQVDVLVRGLVAQVLGHGGAESVPADRAFRELGFDS 6779 Query: 1500 LMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTD 1559 L AV+LR R+ G + TLV D+P + AD+L E+ G+ + T A V TD Sbjct: 6780 LTAVDLRNRLNAATGLRLASTLVFDYPTPAVLADHLWSELAGVRQSTAGPVAGPVVG-TD 6838 Query: 1560 DPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYT 1617 +PIA+V ++CR+PG + P+ W LLAGG D I E P DR WD++ +DPDP+ G +YT Sbjct: 6839 EPIAIVGMACRYPGGVESPDELWGLLAGGGDGISEFPADRGWDLESLFDPDPNRSGTSYT 6898 Query: 1618 RXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVF 1677 R P FFGISPREA+ ++PQQRL+LE WE E AG P LRGSRTGVF Sbjct: 6899 RHGGFLYGAAEFDPGFFGISPREALAMDPQQRLLLEASWESFESAGLDPQRLRGSRTGVF 6958 Query: 1678 TGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVA 1737 GV ++YA L + ++E + TG + + +SGRVA+ G EGPAV VDTACSS+LVA Sbjct: 6959 AGVMYHDYASRLM-DLPTEVEGYVGTGTSGSVLSGRVAYTFGLEGPAVTVDTACSSSLVA 7017 Query: 1738 VHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEG 1797 +H A QAL+SG+CDLALAGGV V+ +P T + SR R LS GRCK+F ASADG SEG Sbjct: 7018 LHLAAQALRSGECDLALAGGVTVMATPGTFIEFSRQRGLSQDGRCKSFAASADGTGWSEG 7077 Query: 1798 CGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSG 1857 GVL+++RLSDA R+G ++ AV+ ++VNQDGAS+GLT PNG +QQR+I LA A LS Sbjct: 7078 VGVLLVQRLSDAQREGRKIYAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALASARLSP 7137 Query: 1858 ADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLI 1917 +DVD +EAHGTGT LGDPIE Q PL +GSVK+NIGHT++A+G AG+I Sbjct: 7138 SDVDVVEAHGTGTTLGDPIEAQAVLATYGQDRQGREPLWLGSVKSNIGHTQAAAGVAGVI 7197 Query: 1918 KVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTN 1977 K+V++++HG++P +LH + PSPH+ W A V + EP PW R RRA VSSFG +GTN Sbjct: 7198 KMVMAMRHGLVPATLHVDEPSPHVDWSAGAVALATEPTPWPAVDRPRRAAVSSFGISGTN 7257 Query: 1978 AHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV-LALSARSPEALVELARRYDDWLS 2036 AHV++E+ P + D P V + LSARS AL A R+ WL+ Sbjct: 7258 AHVIIEQPPAE----------TIEGEIVARDLPPVVPVLLSARSDAALAGQAGRWARWLA 7307 Query: 2037 ATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRP 2096 A DV ++ R E RA VV VV G R Sbjct: 7308 ADEAPRPLDVAWSSVTTRPALEQRAVAVVADGNDLLTALRALDASEPSGTVVTGSTAVRG 7367 Query: 2097 TTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET-AD 2155 A LF+GQG+Q GM REL+ PVFA + + + +LPRPL +VLFA+ A Sbjct: 7368 QLALLFSGQGAQRAGMGRELYAGFPVFATALDEVCGHLDPLLPRPLREVLFASSGSAEAG 7427 Query: 2156 LLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMA 2215 LL T F Q LFAVE+ L RL +S+ + PDVV GHS+G+ AA VAGV SL D +L+A Sbjct: 7428 LLDQTVFTQAGLFAVEVALFRLVESFGVVPDVVAGHSIGEVTAAHVAGVLSLADACQLVA 7487 Query: 2216 ERGRMFGSLPEGGRMVAVFAD-AEHVEQVAGEFPRVSVGAYNGPN-TVLSGPGEDLEEIV 2273 RGR+ +LP GG M+AV AD A VE +AG R V A NGP V+SG E L+E+ Sbjct: 7488 ARGRLMQALPTGGGMLAVAADEAAVVESIAGLADRAGVAAVNGPTAVVVSGAVEALDEVE 7547 Query: 2274 ERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQT 2333 + D G+R L SHAFHS L++P+LD P LP+V N TGA+ Sbjct: 7548 RAWRDRGVRTRRLTVSHAFHSPLMEPMLDEFRTILHGLTFATPLLPVVSNVTGALADADE 7607 Query: 2334 PLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVA 2393 A YW RH R V+FA+ + + A G +E+GPQ VLT A V P A AVA Sbjct: 7608 IRTADYWVRHVRDAVRFADGITALKAAGIDTFLEVGPQSVLTAMAADVLPGDDAV-LAVA 7666 Query: 2394 SLRKGVADRRQIADALASAYVGGHRPDFAAVHRQP-RRPVELPTYPFQRRRFWPKAS--- 2449 R+ + + ALA +V G + + R V+LPTY FQ +R+WP+ + Sbjct: 7667 VQRRDRPEAHALLHALAELHVHGVPVTWQSWFADTGARRVDLPTYAFQHQRYWPEGTPTR 7726 Query: 2450 SIAVDGG 2456 A +GG Sbjct: 7727 QAAPEGG 7733 Score = 780 bits (2013), Expect = 0.0 Identities = 561/1557 (36%), Positives = 755/1557 (48%), Gaps = 92/1557 (5%) Query: 3 SAEHPIEPTPSFAIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFDPD 60 +A P P AI+ A RFPG S+ +E W LL DG +A++ +P DR WD++ FD D Sbjct: 8357 TAARPAADEP-IAIVSMACRFPGGVSSPQELWRLLADGVDAVTPMPADRGWDLDALFDSD 8415 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P G TR GF+ DV GFDA FFG++ RE MDPQ R+L+ T W A EH+GI P Sbjct: 8416 PEQVGTSYTRSGGFLHDVAGFDAAFFGINPREALAMDPQQRLLLHTTWEAFEHAGIDPHR 8475 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 + S TGVF+G DY + ++E Y A G + +GR++Y GL GPAV V Sbjct: 8476 VRGSATGVFMGTNGQDYATLLLGARA--QVEGYQATGNGASVVSGRLAYSFGLHGPAVTV 8533 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVA+H A QALR ECDLALAGG V+ TP + FS LA DGR K F Sbjct: 8534 DTACSSSLVALHLATQALRSGECDLALAGGVTVMSTPGAFLEFSRQRGLAADGRVKAFAE 8593 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADG GEG GV++++RL DA RDG+RI AV+RGSA+N DGAS GLT PNG AQQRVI Sbjct: 8594 AADGTGWGEGVGVLLLQRLSDAQRDGNRILAVVRGSAVNSDGASNGLTAPNGPAQQRVIR 8653 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 AL AGL PADV +EAHGTGT+LGDPIEAQA G R + PL +GS K+NIGH Sbjct: 8654 HALDNAGLTPADVDVVEAHGTGTTLGDPIEAQALLATYGRDRTADRPLWLGSVKSNIGHT 8713 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 + L++E LPK L+ + P+PH+ W + ++ E PW PR AG Sbjct: 8714 QAAAGAASLIKMVLALQHEVLPKTLHVDAPTPHVDWSSGTLALLTEARPWTTTEGPRRAG 8773 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL 480 VSSFG +GTNAHVILE+AP P + + P P+SA AL AG D Sbjct: 8774 VSSFGISGTNAHVILEQAPDRPEPVFPDG-DRPAAILPWPVSAADLPALREQAGRLAD-- 8830 Query: 481 RAHPQARLAD-VSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 RA AD V+ RAHL +RA +V R + L ALA P +V Sbjct: 8831 RAATGDDPADLVAWALADGRAHLGRRATVVAADRATRTAALRALAAGEEHPAVVTAR-RR 8889 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 A F+GQG+Q PG R L+DT PVFA + + + L +PL V+F A+ G Sbjct: 8890 GGGLAVQFSGQGAQRPGAGRRLYDTFPVFAAALDEVCAVLDHQLPQPLKPVLFAAE---G 8946 Query: 600 DTESPLR-HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDG 658 E+ L T + Q LFA+E+ L RL +S+G P V GHS+G+ +AA VAGV + D Sbjct: 8947 SAEATLLDETVFTQAGLFALEVALFRLVESFGVVPGHVAGHSIGEITAAHVAGVLSLADA 9006 Query: 659 ARLIAERGRLFGSLPAGGRMAAVFTAPERA--ERLTDEYPSLSVAAYNGANTVLSGPAKD 716 A L+A RGRL +LPAGG M AV A E A E L + VAA NG V+ A D Sbjct: 9007 ATLVAARGRLMQALPAGGGMLAV-AADEAAVVESLAGLGDRVGVAAVNGPTAVVLAGALD 9065 Query: 717 LESAVATLVAD-GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGS 775 + L + GVR L SHAFHS L++P+L DF + L + P ++ N TG Sbjct: 9066 ALDGLERLWRERGVRTRRLRVSHAFHSPLMEPMLTDFRAVLDGLTFAAPLLPIVSNLTGR 9125 Query: 776 ALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPAT 835 YW RH R+ V +A + L D LE+GP+ VLTA PD A Sbjct: 9126 LAEPDEIRTPGYWVRHVREAVRYADGIAALRDAGVDTFLELGPQAVLTAMTAGLLPD-AD 9184 Query: 836 TPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFR------QPDARKL-DLPTYPFE 888 +A+LR + + A+A + G D+ A +PD R L +LPTY F Sbjct: 9185 DGTAVAALRAGADEPAALLAALAVVHGTGRDVDWAAVLAALAGPRPDRRLLPELPTYAFR 9244 Query: 889 HRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVL 948 +++W + DT A A P R + DG + L G D+ +L Sbjct: 9245 PQRYWPT------LDTLPAPAAD-DPVDDAFWRAVTDGDLGRL-----GLDPDQPMRELL 9292 Query: 949 NKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTA 1008 +L + +++ RY + W+ W++V ALTA Sbjct: 9293 PELESWRRRRQLDGTLAGWRYRVTWERRALTVADPGT---WLVVAPPHQVTERVLAALTA 9349 Query: 1009 GGHR-HQIVALPGSDADEAQLVDTLRAASAGE-LYVVHIAAGDGAAAPMRDLLRVQHRTL 1066 G H + P + + D R A+A + ++ + A D A P + L Sbjct: 9350 GAATVHLLTVDPATVTRDGLTADLDRLAAAHQPTALLSLLALDEAPHPEQSALPT----- 9404 Query: 1067 GGLRRLFRAANDAELRS----PIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHI 1122 GL RS P+WL T V V P Q+ WG G AALE P Sbjct: 9405 -GLAANLLLVQAHTGRSGPAVPLWLATTGAVAVGGEAVVHPTQATTWGLGLVAALEHPRH 9463 Query: 1123 WGGLADLSG--ADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVR 1180 GG+ DL A+ + L + + DGEDQ+A+R V+ RLVR TG P+ R Sbjct: 9464 VGGVVDLPADPAEAAYAALAGALVNV-DGEDQLAVREAGVHTRRLVRDTGLPAAGD-GYR 9521 Query: 1181 EDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVI 1240 + T L+TGG G + +L HGA + L EP Sbjct: 9522 PNGTVLLTGGTGPLARHTTDWLGRHGAEVLPLA---EP---------------------A 9557 Query: 1241 TADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWH 1300 T + D LM +AAE P+ +VH E G+ PL+ L A + A V Sbjct: 9558 TGKLGD------LMERLAAEERPVTALVHVPAETGSVPLTELTLAALAADLAATVGDVPR 9611 Query: 1301 LSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFG 1360 ++ L LD FV +S VWG G+ A +A L LA LR G+ A +V +G Sbjct: 9612 YADELA--HRPLDAFVLCTSTTGVWGAGGRAGQSAGDALLHALAASLRHGGLAATAVAWG 9669 Query: 1361 PWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAG 1420 PW AE + +L +RG+ L P A+ + +VA + W RF+P + Sbjct: 9670 PWRDDPESAE-QTQLRRRGLPGLPPELAVEAFGQALRAQGALIVADVRWDRFVPTFASMR 9728 Query: 1421 RRAFLSEL-ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT 1479 + L+ + E+ L E+L R+ ++ + + A V Sbjct: 9729 QCPLLTGVPEAGAAMPADDERRPADDEAATALRERLRPLSPADREGVLVDLVGGLAATVL 9788 Query: 1480 RVDADE-IRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYL 1535 D + + F ++G DS+ AVELR R+ G +P +V D+P + A +L Sbjct: 9789 GHGGDAGLEPDRAFREVGFDSMTAVELRNRLRAATGVHLPAAVVFDYPTPAALARHL 9845 Score = 710 bits (1832), Expect = 0.0 Identities = 421/944 (44%), Positives = 549/944 (58%), Gaps = 23/944 (2%) Query: 1528 LSDAADYLLVEVL--GLGEQTNVRQAST-VTARTDDPIAVVAVSCRFPGA-PDPESFWEL 1583 +S +AD + VE L L E +RQ + +TA +PIA+VA+SCR+PG PE W+L Sbjct: 1 MSTSADKV-VEALRASLKETGRLRQLNQQLTAAAREPIAIVAMSCRYPGGVASPEQLWDL 59 Query: 1584 LAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAV 1642 +A G DAI P DR WD+D YDPD D G++ TR EFFGISPREAV Sbjct: 60 VAAGGDAIGGFPTDRGWDLDNLYDPDADRAGRSTTREGGFLYDAADFDAEFFGISPREAV 119 Query: 1643 WIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFI 1702 ++PQQRL+LET WE E AG AP+ +RG + GVF G AAN Y +E+ E + + Sbjct: 120 AMDPQQRLLLETSWEAFEHAGIAPASMRGQKVGVFVGTAANGYGMGPQSEAEGADEGYLL 179 Query: 1703 TGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLL 1762 TG A + +SGR+A+ALG EGPAV VDTACSS+LVA+H ACQAL+ GD DLALAGGV V+ Sbjct: 180 TGTATSVVSGRIAYALGLEGPAVTVDTACSSSLVALHLACQALRQGDFDLALAGGVCVMA 239 Query: 1763 SPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPA 1822 +P V SR R L+P GRCK+F A+ADG SEG G+L+++RLSDA R G + AVI Sbjct: 240 TPGPFVGFSRQRGLAPDGRCKSFAAAADGTGWSEGVGILLVERLSDAQRKGHPILAVIRG 299 Query: 1823 SSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXX 1882 S+VNQDGAS+GLT PNG AQQR+I LA A L+ ADVD +EAHGTGT LGDPIE Q Sbjct: 300 SAVNQDGASNGLTAPNGPAQQRVIRQALANARLTTADVDAVEAHGTGTVLGDPIEAQALL 359 Query: 1883 XXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIP 1942 PLL+GS+K+NIGH++SA+G AG+IK+V++++HG++P +LH + P+P + Sbjct: 360 ATYGRDRPADRPLLLGSIKSNIGHSQSAAGVAGVIKMVMAMRHGLVPSTLHVDEPTPKVD 419 Query: 1943 WDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXX 2002 W A V ++ E PW R RRA VSSFG +GTNAH ++EE P Sbjct: 420 WSAGEVSLVTESTPWPATDRPRRAAVSSFGISGTNAHTIIEEPP------TPDAVEPADA 473 Query: 2003 XXXGTDDSPQV-LALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRA 2061 T P V + LSARS AL A R+ WL L DV ++ V RS E+RA Sbjct: 474 GPAPTVALPAVPVLLSARSEAALGAQAGRWTRWLEDDEALRTVDVGWSSVVSRSALEHRA 533 Query: 2062 ALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQP 2121 L +V G+ R A LF+GQG+Q GM REL+ P Sbjct: 534 VLTATDREELLAGLRALAAGQPSGALVAGQAADRGPLAVLFSGQGAQRAGMGRELYAEFP 593 Query: 2122 VFAQTVRQCAEAVADMLPRPLLDVLFATDRET-ADLLQHTSFAQPALFAVEMGLARLWQS 2180 VFA + + + +LPRPL +VLFA + A+LL T F Q LFAVE+ L RL +S Sbjct: 594 VFAAALDEVCAQLDALLPRPLKEVLFAPEGSAEAELLDRTVFTQAGLFAVEVALFRLVES 653 Query: 2181 WAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHV 2240 + + PD+V GHS+G+ AA VAGV SL D L+A RGR+ +LP GG M+AV A V Sbjct: 654 FGVAPDMVGGHSIGEVTAAHVAGVLSLADACELVAARGRLMQALPAGGGMLAVAAAEADV 713 Query: 2241 EQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDP 2299 V V A NGP + V+SG E L+E+ + G+R L+ SHAFHS L++P Sbjct: 714 LATLDGSTGVGVAAVNGPTSVVVSGAVEALDEVERVWRGRGVRTRRLSVSHAFHSPLMEP 773 Query: 2300 VLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAA 2359 +LD P LP+V N TGA+ A YW RH R+ V+FA+ V + A Sbjct: 774 MLDEFRVVLDGLTFEAPALPVVSNVTGALADVDEIRSADYWVRHVREAVRFADGVAALRA 833 Query: 2360 LGCSVLMEIGPQPVLTGAAVQVWPEHMAAPR-------AVASLRKGVADRRQIADALASA 2412 G +EIGP+ VLT V A AV +LR + R + AL+ Sbjct: 834 AGVDTFLEIGPRSVLTAMTRDVLSGREPADADDDTPVVAVPALRADRPESRALLAALSEL 893 Query: 2413 YVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSIAVDG 2455 +V G D+AA++ PV LPTY FQR+R+WP+ + G Sbjct: 894 HVNGTPVDWAALYAGTGATPVALPTYAFQRQRYWPEQMPASATG 937 Score = 654 bits (1686), Expect = 0.0 Identities = 387/903 (42%), Positives = 506/903 (56%), Gaps = 16/903 (1%) Query: 15 AIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G A R+PG ++ WALL G + IS+ P DR WD+E FDPDP G TR Sbjct: 5098 AIVGMACRYPGGVDGPDQLWALLAGGGDGISEFPTDRGWDLESLFDPDPEHSGTSYTRHG 5157 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ FD FFG+S RE MDPQ R+L+E +W + E +G+ P L S TGVF G+ Sbjct: 5158 GFLYGAAEFDPGFFGISPREALAMDPQQRLLLEASWESFESAGLDPQRLRGSRTGVFAGV 5217 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 HDY D P+ E ++ GTS + +GR++Y GL+GPAV VDTACSSSLVA+H Sbjct: 5218 MYHDYASRLMD--LPPDAEGFVGTGTSGSVLSGRVAYTFGLEGPAVTVDTACSSSLVALH 5275 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR ECDLALAGG V+ TP T I FS L+ DGRCK+F A+ADG EG G Sbjct: 5276 LAAQALRSGECDLALAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASADGTGWSEGVG 5335 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V++V+RL DA R+G R+ AV+RGSA+NQDGAS GLT PNG +QQRVI AL A L PAD Sbjct: 5336 VLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLTPAD 5395 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT+LGDPIEAQA G R + PLL+GS K+NIGH + Sbjct: 5396 VDAVEAHGTGTTLGDPIEAQALLATYGQERPQDRPLLLGSVKSNIGHTQAAAGVAGVIKM 5455 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + +P L+ + SPH+ W + + E PW R +PR A VSSFG +GTNAH Sbjct: 5456 VLAMRHGVVPATLHVDEASPHVDWSAGAVALATEPTPWPRVDRPRRAAVSSFGISGTNAH 5515 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVS 492 VI+E+ PA + P VL LSAR AL AG + WL A R DV+ Sbjct: 5516 VIIEQPPAETIEGEVVAGDVPPVVPVL-LSARDAAALSAQAGRWARWLTADEAPRPLDVA 5574 Query: 493 HTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQGS 552 ++ T R LE RA + R+ + L ALAD P +V G + + + A LF+GQG+ Sbjct: 5575 WSSVTTRPALEHRAVVTAADRDDLVAALTALADGDPTGTVVSGATGQRGRLALLFSGQGA 5634 Query: 553 QYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESP-LRHTTYA 611 Q GM REL PVFA + + + +L +PL +V+F + G E+ L T + Sbjct: 5635 QRAGMGRELSAGFPVFAAALDEVCGHLDPLLPRPLREVLFAS---AGSAEAELLDQTVFT 5691 Query: 612 QPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGS 671 Q LFAVE+ L RL +S+G PD++ GHS+G+ +AA VAGV + D L+A RGRL + Sbjct: 5692 QAGLFAVEVALFRLVESFGIVPDMLAGHSIGEVTAAYVAGVLSLADACALVAARGRLMQA 5751 Query: 672 LPAGGRMAAVFTAPERA--ERLTDEYPSLSVAAYNGAN-TVLSGPAKDLESAVATLVADG 728 LP GG M AV A E A E + VAA NG V+SG + L+ G Sbjct: 5752 LPTGGGMLAV-AADEAAVVESIAGLADRAGVAAVNGPTAVVVSGAVEALDEVERHWRDRG 5810 Query: 729 VRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYW 788 VR L SHAFHS L++P+LD+F + L + P ++ N TG+ G R YW Sbjct: 5811 VRTRRLMVSHAFHSPLMEPMLDEFRTVLDGLTFSAPLLPVVSNVTGALAGDEIR-TADYW 5869 Query: 789 RRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTA 848 RH R V FA + L LE+GP+ VLTA A P V R Sbjct: 5870 VRHVRDAVRFADGITALRAAGIDTFLEVGPQSVLTAMAADVLPGDDAVLAVAVQRRDRPE 5929 Query: 849 DHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTA 907 H + A+A + G +++ F AR++DLPTY F+H+++W + RA D A Sbjct: 5930 AH-ALLHALAELHVHGVPVTWQSWFADTGARRVDLPTYAFQHQRYWPTAGRARTGDVSGA 5988 Query: 908 SAG 910 G Sbjct: 5989 GLG 5991 Score = 640 bits (1652), Expect = 0.0 Identities = 379/906 (41%), Positives = 503/906 (55%), Gaps = 19/906 (2%) Query: 15 AIIGYAARFPGAAS-AEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G A R+PG + ++ W L+ G + I + P DR WD++ F PDP PG TR Sbjct: 3351 AIVGMACRYPGGVTNPQQLWDLVAAGADGIGEFPTDRGWDLDRLFHPDPDNPGTSYTRHG 3410 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ FD FFG+S RE MDPQ R+L+E +W E +G+ P+ L S TGVF GL Sbjct: 3411 GFLYGAAEFDPDFFGISPREAIAMDPQQRLLLEASWETFESAGLDPSRLRGSRTGVFAGL 3470 Query: 133 ATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 HDY D PE + Y+ GTS + +GR++Y GL+GPAV VDTACSSSLVA+ Sbjct: 3471 MYHDYASGVQD---LPEGVGGYLGTGTSGSVLSGRVAYTFGLEGPAVTVDTACSSSLVAL 3527 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR ECDLALAGG V+ TP T I FS L+ DGRCK+F A+ADG EG Sbjct: 3528 HLAVQALRGGECDLALAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASADGTGWSEGV 3587 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 GV++V+RL DA R+G R+ AV+RG+A+NQDGAS GLT PNG +QQRVI AL A L A Sbjct: 3588 GVLLVERLSDAQRNGHRVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANARLTAA 3647 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT+LGDPIEAQA G R + PL +GS K+NIGH + Sbjct: 3648 DVDAVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSVKSNIGHTQAAAGAAGIIK 3707 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 + + LP L+ + PSPHI W + ++ E W G+PR A +SSFG +GTNA Sbjct: 3708 MIMAMRHGVLPSTLHVDEPSPHIEWSAGEVSLLTEARDWPAAGRPRRAAISSFGVSGTNA 3767 Query: 432 HVILEEAPAVGTPATTEPVEDP---RRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARL 488 HVI+E+ PA P E P + S + LSAR+ A+ A + W+ + R Sbjct: 3768 HVIIEQPPAEAEPTRGEGAPTPTAGQLPSPVLLSARSEAAVAAQAERWARWIAGDEELRP 3827 Query: 489 ADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFT 548 DV ++ +RA +E RA R+ + L ALAD PA +V G + A LF+ Sbjct: 3828 LDVGWSSTVSRAVMEHRAVATATDRDELLAGLRALADGEPAATVVTGTGATRTQLAVLFS 3887 Query: 549 GQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHT 608 GQG+Q GM REL+ PVFA + + + +L + L +V+F A + E L T Sbjct: 3888 GQGAQRAGMGRELYAGFPVFATALDEVCAQLDPLLPRALREVLF-ASAGTAEVEL-LDQT 3945 Query: 609 TYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRL 668 + Q LFAVE+ L RL +S+G PDVV GHS+G+ +AA VAGV + D L+A RGRL Sbjct: 3946 VFTQAGLFAVEVALFRLVESFGVVPDVVAGHSIGEVTAAYVAGVLSLADACALVAARGRL 4005 Query: 669 FGSLPAGGRMAAVFTAPER--AERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLV 725 +LP GG M AV A E AE L L +AA NG A V+SG + L+ Sbjct: 4006 MQALPTGGGMLAV-AADEAAVAESLAGMTDRLGIAAVNGPAAVVVSGAVEALDEVERVWR 4064 Query: 726 ADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDG 785 GVR L SHAFHS L++P+LD+F + L +R P ++ N TG+ Sbjct: 4065 ERGVRTRRLTVSHAFHSPLMEPMLDEFRAVLAGLTFRAPLLPVVSNLTGALADPQEITRA 4124 Query: 786 AYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRP 845 YW RH R+ V +A + L LEIGP+ VLTA + A V RP Sbjct: 4125 EYWVRHVREAVRYADGIAALRATGVDTFLEIGPQSVLTAMNADLLAEDALAVAVQRRDRP 4184 Query: 846 TTADHRQITEAVAAAYAAG-HLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDT 904 + + A+A + G + + F A ++DLPTY F+H+++W +A D Sbjct: 4185 AP---QALLHALADLHVHGVPVTWTQWFTDAGAARVDLPTYAFQHQRYWLGAGQARAADV 4241 Query: 905 QTASAG 910 A G Sbjct: 4242 SGAGLG 4247 Score = 162 bits (410), Expect = 9e-37 Identities = 119/354 (33%), Positives = 165/354 (46%), Gaps = 16/354 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRR-DPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TGG GA+G H A + A GA +VLTSRR + A DE+T R+ AAD+ Sbjct: 1220 LVTGGTGALGAHVARWAAANGAEHLVLTSRRGEHAPGAAELRDELTGLG-ARVTLVAADM 1278 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D A+V LL + A+ PL + H AGV +L + L K GA H Sbjct: 1279 ADRARVEALLRDVDADPAPLTAVVHAAGVGQLTMLVDTDLAGLAGVLDGKIAGAVHLDEL 1338 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQA YA NA LD L +RRA+GL AT + +GPW +GG Sbjct: 1339 LGDRPLDAFVLFSSIAGIWGSGGQAAYAAGNAFLDALAERRRARGLAATAVAWGPWAEGG 1398 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP-P 3535 MAS E + +GL P+ P+ A++AL + TV +W +AR P Sbjct: 1399 MASGEGQEL-LARRGLSPMSPAQAVYALRSAVGRAVPSVTVADVDWSLFTPAFAAARARP 1457 Query: 3536 ILD--------LVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 +LD L + A E T L + L+ +P ++ +T+ ++ L + Sbjct: 1458 LLDDVAEARDALRVVDAEPEDTAGGGLRQHLLTLPRAEQDRHLTDLVRTHTAAVLGHSGT 1517 Query: 3588 P--AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 A F +LG DSL A+ELRNRL + G T+ T VFDYP LA++L Sbjct: 1518 DLVKAGRAFKELGFDSLTAVELRNRLGAATG--LTLPTTLVFDYPNPAALADHL 1569 Score = 154 bits (388), Expect = 3e-34 Identities = 115/352 (32%), Positives = 162/352 (46%), Gaps = 21/352 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +L GA ++VL SRR P +A A + + E R+ A DV Sbjct: 7999 LVTGGTGALGRHVARWLLANGAAEVVLASRRGP--AAPGAAELVAELGAVRV--VACDVT 8054 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPE-RFRTTLAPKAYGASHXXXX 3416 D A V L++ LP L + H AG + + + TLA K GA H Sbjct: 8055 DRAAVEALVSG----LPELTAVVHTAGASGGTAAAHEVTDGELSETLAGKVLGALHLDTA 8110 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQA YA NA+LD LVA RRA+GL AT + +GPW + G Sbjct: 8111 CRGRDLDAFVVFSSVAGVWGGGGQAGYAAGNALLDTLVAARRAKGLPATALAYGPWAEDG 8170 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP- 3535 MA+ E A + +G PL P AA+ AL + ++ +W R +ARP Sbjct: 8171 MAAGETAD-GLRRRGFSPLAPDAAVAALGRWVNAPEAAPVIVDVDWSRFVTAFTAARPSH 8229 Query: 3536 ILDLVLPSAAGE------ATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL--RLASP 3587 + D V P+ AGE L +L +P + + + ++ E L Sbjct: 8230 LFDRVAPAVAGEPQRPENTAATDGLRNRLATLPATGQEALLVDLVRAEAAAVLGHPTTDQ 8289 Query: 3588 PAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 A F +LG DSL A++LR+RL G T+ +T VFD+P+ LA +L Sbjct: 8290 VPAGRAFRELGFDSLAAVQLRDRLGRVTG--LTLPSTVVFDHPSAAELARFL 8339 Score = 137 bits (344), Expect = 4e-29 Identities = 112/356 (31%), Positives = 156/356 (43%), Gaps = 16/356 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKC---RIHTYA 3353 L+TGG G++G + +L G +VL SR+ P A DE+ R A Sbjct: 2981 LVTGGTGSLGALVSEHLVTAYGVRSLVLVSRQGP---AAPGADELVRRLAALGATARVVA 3037 Query: 3354 ADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHX 3413 DV D +V +L+ I A+ LAG+ H AGVLDD ++S +R LAPK Sbjct: 3038 TDVTDRERVGELVRSITAD-DRLAGVVHTAGVLDDGIVSGITADRLADVLAPKVTAGWWL 3096 Query: 3414 XXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWG 3473 PGQA YA NA LD L R +GL A + +G W Sbjct: 3097 HEATAELDLDLFVLFSSVAGVLGSPGQAAYAAGNAFLDALAVLRAQRGLPAVSLAWGMWD 3156 Query: 3474 QGGMASS--EAATANITAQGLIPLDPSAALHALAEVIANGSGQ--ATVLKANWQRAAKVL 3529 GMA+S +A A +T GL+P+ L + +G V+ RA Sbjct: 3157 TDGMAASINDADRARVTRAGLVPMTAPVGLGLWDAALTHGGAALVPAVVDLPAMRAQTAA 3216 Query: 3530 GSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA 3589 G + LV P+A +G +L + + V ++ + L A Sbjct: 3217 GRVPVMLRGLVGPAAKRRRSGTGAWADRLAGLDPQEARTQVALLVRGMIAQVLGHGGAEA 3276 Query: 3590 --ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A F +LG DSL A+ELRNR++S G + T +T VFDYPT G L+E+L QL Sbjct: 3277 VPADRAFRELGFDSLTAVELRNRINSASGLRLT--STLVFDYPTPGALSEHLYEQL 3330 Score = 135 bits (339), Expect = 2e-28 Identities = 115/362 (31%), Positives = 159/362 (43%), Gaps = 18/362 (4%) Query: 3294 DRSYLITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTY 3352 D + L+TGG GA+G A +L + G +VL SRR P+ + + E + Sbjct: 6464 DGAVLVTGGTGALGALVAEHLVSVHGVRSLVLVSRRGPEAAGAGELSERLSALGASVRVV 6523 Query: 3353 AADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASH 3412 A DV D QV L+A + AE LAG+ H AGVLDD ++ ER LAPK Sbjct: 6524 ACDVTDRDQVFGLVAEVAAE-GRLAGVVHTAGVLDDGVVEGLTAERLAGVLAPKVSAGWF 6582 Query: 3413 XXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPW 3472 PGQ+ YA NA LDGL RR GL A + +G W Sbjct: 6583 LHEATASLDLDLFVVFSSVAGVLGSPGQSAYAAGNAFLDGLAVHRRQLGLPAVSLAWGMW 6642 Query: 3473 GQGGMASS--EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQ---RAAK 3527 GMA+S EA A GL P+ L + G+ +A ++ A A Sbjct: 6643 DTAGMAASIDEADRARSARAGLTPMSAEIGLELFDAAL--GADRAVLVPAVIDVPALRAA 6700 Query: 3528 VLGSARPPILDLVL-----PSAAGEATGD-SELLKQLMEIPIPQRAGFVTEFLQREVQNF 3581 G P +L ++ AG+ G ++ L L E + + L +V Sbjct: 6701 TSGGPVPAVLRTLIGVTGTRRQAGQGGGGWADRLAGLTEDEGRAQVDVLVRGLVAQVLGH 6760 Query: 3582 LRLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 S P A F +LG DSL A++LRNRL++ G + +T VFDYPT LA++L Sbjct: 6761 GGAESVP-ADRAFRELGFDSLTAVDLRNRLNAATG--LRLASTLVFDYPTPAVLADHLWS 6817 Query: 3642 QL 3643 +L Sbjct: 6818 EL 6819 Score = 129 bits (324), Expect = 9e-27 Identities = 113/359 (31%), Positives = 153/359 (42%), Gaps = 13/359 (3%) Query: 3294 DRSYLITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTY 3352 D + L+TGG GA+G A +L G +VL SRR + + + E + Sbjct: 4723 DGAVLVTGGTGALGALVAEHLVSAHGVRSLVLVSRRGAEAAGAGELSERLSALGASVRVV 4782 Query: 3353 AADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASH 3412 A DV D QV L+A + A LAG+ H AGVLDD ++ ER LAPK Sbjct: 4783 ACDVTDRDQVFGLVAEVAAG-GRLAGVVHTAGVLDDGVVEGLTAERLVGVLAPKVSAGWL 4841 Query: 3413 XXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPW 3472 PGQ+ YA NA LDGL RR GL A + +G W Sbjct: 4842 LHEATASLALDLFVVFSSVAGVLGSPGQSAYAAGNAFLDGLAVYRRQLGLPAVSLAWGMW 4901 Query: 3473 GQGGMASS--EAATANITAQGLIPLDPSAALHAL--AEVIANGSGQATVLKANWQRAAKV 3528 GMA+S EA A GL P+ L A V + V+ RAA Sbjct: 4902 DTAGMAASIDEADRARSARAGLTPMSAEIGLELFDAALVAERPALVPAVIDVPAMRAALG 4961 Query: 3529 LGSARPPILDLVLPSAAG--EATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 G P +L ++ S A A + QL + + + ++ V L Sbjct: 4962 AGPV-PAVLRTLIGSTAARRRAARSGDWANQLAGLAPDEARAQIDVLVRGLVAQVLGHGG 5020 Query: 3587 PPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A A F +LG DSL A++LRNRL++ G + +T VFDYPT LA++L Q+ Sbjct: 5021 AEAVPADRAFRELGFDSLTAVDLRNRLNAATG--LRLASTLVFDYPTPAVLADHLHEQV 5077 Score = 75.1 bits (183), Expect = 2e-10 Identities = 83/368 (22%), Positives = 123/368 (33%), Gaps = 49/368 (13%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG G + HT +L + GA + L Sbjct: 9527 LLTGGTGPLARHTTDWLGRHGAEVLPLAEPAT---------------------------- 9558 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 ++ DL+ R+ AE P+ + H+ L+ LA Sbjct: 9559 --GKLGDLMERLAAEERPVTALVHVPAETGSVPLTELTLAALAADLAATVGDVPRYADEL 9616 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 G+A + +A+L L A R GL AT + +GPW Sbjct: 9617 AHRPLDAFVLCTSTTGVWGAGGRAGQSAGDALLHALAASLRHGGLAATAVAWGPWRDD-- 9674 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 A + +GL L P A+ A + + G V W R S R L Sbjct: 9675 -PESAEQTQLRRRGLPGLPPELAVEAFGQAL-RAQGALIVADVRWDRFVPTFASMRQCPL 9732 Query: 3538 DLVLPSAAGEATGDSE-----------LLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 +P A D E L ++L + R G + + + L Sbjct: 9733 LTGVPEAGAAMPADDERRPADDEAATALRERLRPLSPADREGVLVDLVGGLAATVLGHGG 9792 Query: 3587 PPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLP 3644 F ++G DS+ A+ELRNRL + G + A VFDYPT LA +L +L Sbjct: 9793 DAGLEPDRAFREVGFDSMTAVELRNRLRAATG--VHLPAAVVFDYPTPAALARHLRDRLA 9850 Query: 3645 DAEAPETA 3652 + A A Sbjct: 9851 EDGAAAAA 9858 Score = 43.9 bits (102), Expect = 0.48 Identities = 51/208 (24%), Positives = 76/208 (36%), Gaps = 22/208 (10%) Query: 2762 YTLGWHEVPPPPSADDAVGTWLI----AGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAH 2817 Y +GW V P P A G WL+ +G D AK D + L++A Sbjct: 7788 YRIGWEPVRPAP-ATRLSGRWLVVTVDSGADAGVAKT--LTQAGARVDTLTVSSTLARAE 7844 Query: 2818 A-------RGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLP 2870 G G++GV+ C P + + L+ A+ L Sbjct: 7845 LGERLGRISGDGWAGVL--CVLPRQDRPLADTPAVPAGTAVLLTLVRAL-----TDTGLA 7897 Query: 2871 GGLWIVTEHGVACESGEPVDPVQAAL-WGFGRTTINEEPALHCRLVDCDGSSEAVDXXXX 2929 G +W ++ + +GE V AAL WG GR E+P LVD ++ Sbjct: 7898 GRVWALSRTAMPVTAGERAGDVWAALAWGLGRVVALEQPDRWGGLVDLPDRADRGARAGL 7957 Query: 2930 XXXXPGIQEPEIAVRQGKLLASRLLPWA 2957 ++AVR+ L RL+P A Sbjct: 7958 VAVLADGTLDQVAVRRNGLFGRRLVPAA 7985 >tr|Q52V46|Q52V46_9ACTO Tax_Id=255848 SubName: Full=Polyketide synthase type I;[Streptomyces aizunensis] Length = 8147 Score = 1639 bits (4243), Expect = 0.0 Identities = 1139/3011 (37%), Positives = 1545/3011 (51%), Gaps = 183/3011 (6%) Query: 16 IIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAG 73 I+ + RFPG + E+ W LL DG + ++ P DR WD++ + DP G TR G Sbjct: 1693 IVSMSCRFPGGVRTPEDLWQLLADGTDTVAAFPADRGWDLDGLYSADPERSGTSYTREGG 1752 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 F+ D FDA FFG+S RE MDPQ R+L+ETAW E +GI P SL S GVFVG Sbjct: 1753 FLYDAADFDADFFGISPREALAMDPQQRLLLETAWETFERAGIDPASLRGSQAGVFVGTN 1812 Query: 134 THDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 DYL + + E + +E ++ G + + +GR+SY GL+GPA+ VDTACSSSLVA+H Sbjct: 1813 GQDYLSLVTREGDGLDGLEGHVGTGNAASVVSGRLSYVFGLEGPAITVDTACSSSLVALH 1872 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC LALAGG V+ TP + FS LA DGR K F +AADG GEG G Sbjct: 1873 LAVQALRQGECTLALAGGVTVMSTPDAFVDFSRQRGLAEDGRIKAFASAADGTGWGEGVG 1932 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DA R+G + AV+RGSAINQDGAS GLT PNG +QQRVI AL AGL AD Sbjct: 1933 MLLVERLSDARRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALAGAGLSAAD 1992 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G GR + PL +GS K+NIGH + Sbjct: 1993 VDAVEAHGTGTRLGDPIEAQALLATYGQGRPADRPLWLGSVKSNIGHTQAAAGVAGVMKM 2052 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP+ L+ + P+PH+ W + ++ E W G PR AGVSSFG +GTNAH Sbjct: 2053 VMAMRHGVLPRTLHVDGPTPHVDWSAGDVALLTEQREWPATGHPRRAGVSSFGLSGTNAH 2112 Query: 433 VILEEAPAVG-----TPATTEPVEDPRRYSVLPL--SARTPEALVRLAGEYRDWLRAHPQ 485 I+EEAPA T A T P SVLPL SA++ L + + L +P Sbjct: 2113 TIIEEAPADDDAEPTTGAGTAP-------SVLPLLISAKSDAGLRAQSEQLATHLVGNPD 2165 Query: 486 ARLADVSHTAGTARAHLEQRAALV--VNSRESAIELLGALADDRPAPGLVRGESHEAPKT 543 + D++++ T R+ LE RA LV ++R L +LA APGLV+G E Sbjct: 2166 VPIGDIAYSLTTGRSGLETRAILVGDADNRTGLAAALRSLAAGEQAPGLVQGTVTEGG-L 2224 Query: 544 AWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTES 603 A+LFTGQGSQ GM REL++T PVFA+ + + LE PL DV+F G Sbjct: 2225 AFLFTGQGSQRLGMGRELYETYPVFADALDAVCARMD--LEVPLRDVLF------GAYAG 2276 Query: 604 PLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIA 663 L T Y QPALFAVE+ L RL +SWG PD V GHS+G+ +AA VAGV ++D L+ Sbjct: 2277 LLDETAYTQPALFAVEVALFRLVESWGLRPDFVAGHSIGEIAAAHVAGVLSLDDACALVE 2336 Query: 664 ERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVAT 723 RGRL G+LP GG M AV APE AE L +S+AA NG +V+ A D AVA Sbjct: 2337 ARGRLMGALPGGGVMIAV-QAPE-AEVLPLLTERVSIAAINGPQSVVI--AGDEADAVAI 2392 Query: 724 LVA-DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTR 782 + + G + L SHAFHS +D +L+DF + A+ L Y P+ ++ N TG AL Sbjct: 2393 VESFTGRKSKRLTVSHAFHSPHMDGMLEDFRAVAEGLSYEAPRIPVVSNLTG-ALVSDEM 2451 Query: 783 LDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWP-DPATTPQVLA 841 +W RH R+ V F +R L +E+GP VL+A A D A VL Sbjct: 2452 GSAEFWVRHVREAVRFLDGMRVLEAAGVTTYVELGPGGVLSALAQECVSGDGAAFVPVLR 2511 Query: 842 SLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQ-PDARKLDLPTYPFEHRQFWFSDNRAI 900 S RP + A+A A+ G D+ AF +++DLPTY F+ ++FW A+ Sbjct: 2512 SGRP---EAETAVTALAQAHVRGVDVDWAAFFSGTGVQRVDLPTYAFQRQRFW----PAM 2564 Query: 901 DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRS 960 ++ G+V ++E +E LA L+ + V A R Q+ Sbjct: 2565 TAESAPVG-GTVDAVDAHFWDVIEQEDVESLAELLGLDDASAWGSVVPALSAWRRQGQQQ 2623 Query: 961 THVDPDARYEIRWDXXXXXXXXXXXXXDWILV------GDDTAAVLEFADALTAGGHRHQ 1014 VD RY W W++ GDD +A+T G Sbjct: 2624 AQVD-GWRYRASWKPVTAAVSSGVVSGTWVVAVPAGSAGDDARV-----EAVTNG----- 2672 Query: 1015 IVALPGSDADEAQLVDTL---RAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRR 1071 L G D ++V RAA AG L AG+G+ A + LL + GGL Sbjct: 2673 ---LAGRGVDVRRVVVEAGVDRAALAGLL------AGEGSLAGVVSLLGLDES--GGLAA 2721 Query: 1072 ---LFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLA 1127 L +A DA + +P+W +TR V +D +V P Q+ +WG GR AALE+P WGGL Sbjct: 2722 TAGLVQALGDAGVSAPLWCLTRGAVSVGRSDRLVSPVQAQVWGLGRVAALEVPERWGGLV 2781 Query: 1128 DLSGADTEWPRLIARITS--PRDGEDQIALRGDAVYAPRLVRRT---GEPSDTPLPVRED 1182 DL E R ++R+ GEDQ+A+R V+ RLVR G S TP Sbjct: 2782 DLPEVLDE--RAVSRLIGVLAGSGEDQVAVRSSGVFGRRLVRAPRAEGAASWTPTG---- 2835 Query: 1183 RTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITA 1242 T LVTGG G +G VA +LA GA +VLTSRR +V V+ Sbjct: 2836 -TVLVTGGTGVLGGRVARWLAGAGAERLVLTSRRGLDAPGTAELVEELTSSGVEVSVVAC 2894 Query: 1243 DVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLS 1302 D AD + L+++ A L ++H AG + L L +D V K A +L Sbjct: 2895 DAADRDALRALLSSEAGSL---TAVIHTAGVLDDGVLDALTPDRIDGVVRAKAVSALNLH 2951 Query: 1303 EALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW 1362 E +L +L FV SS++ G GQ Y AANA+LD LA + R G+ A S+ +GPW Sbjct: 2952 ELTAELGIELSAFVLFSSMSGTVGTAGQANYAAANAYLDALAEQRRADGLAATSIAWGPW 3011 Query: 1363 AAG--MADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQA 1419 A G ADA AR+ + GV + A+ + VAG + VA ++W RFLP + A Sbjct: 3012 AEGGMAADAALEARMRRDGVPPMPADPAIRALRQAVAGDDAVLTVADVEWDRFLPGFVAA 3071 Query: 1420 GRRAFLSELES--ELXXXXXXXXXXXXXXXXXXLVEQLT-KAPVQQRKSLITNYLRNAVA 1476 SEL + L +L+ +AP +Q + L+ A Sbjct: 3072 RHSELFSELRDVRDARAAQDRAQAAVAADRPDSLSGRLSAQAPAEQERELLDLVRTQVAA 3131 Query: 1477 EVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLL 1536 + + + F +LG DSLMAVELR RI +P TL+ DHP + A++L Sbjct: 3132 VLGHAGVENVGAGRAFKELGFDSLMAVELRNRIGSATELRLPATLIYDHPTSAALAEFLR 3191 Query: 1537 VEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVP 1595 E++G + + V+A +DPIA+V++SCRFPG PE W LL G DA+ P Sbjct: 3192 GELVGTVRVADKVLPAVVSA-DEDPIAIVSMSCRFPGGVRTPEDLWRLLVDGTDAVGAFP 3250 Query: 1596 EDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLET 1654 DR WD+D Y PDPD PG +YTR P FFGISPREA+ ++PQQRL+LET Sbjct: 3251 ADRGWDLDRLYSPDPDQPGTSYTREGGFFDGAADFDPGFFGISPREALAMDPQQRLLLET 3310 Query: 1655 VWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRV 1714 WE +ERAG PS LRGS+ GVF G +Y L++ ES + +E H TGNA + +SGRV Sbjct: 3311 SWEAIERAGIDPSSLRGSQAGVFVGTNGQDYLSLITRES-EGLEGHLGTGNAGSVMSGRV 3369 Query: 1715 AFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRAR 1774 ++ LG EGPAV VDTACSS+LVA+H A QAL+ G+C +ALAGGV V+ +P V SR R Sbjct: 3370 SYVLGLEGPAVTVDTACSSSLVALHWAIQALRQGECSMALAGGVTVMSTPENFVDFSRQR 3429 Query: 1775 MLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGL 1834 L+ GR K F ++ADG EG G+L+++RLSDA R+G V AV+ S+VNQDGAS+GL Sbjct: 3430 GLAEDGRIKAFASAADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGSAVNQDGASNGL 3489 Query: 1835 TVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXP 1894 T PNG +QQR+I A LA AGLS ADVD +EAHGTGT LGDPIE Q P Sbjct: 3490 TAPNGPSQQRVIRAALASAGLSAADVDVVEAHGTGTKLGDPIEAQALLATYGQDRPAGRP 3549 Query: 1895 LLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEP 1954 L +GS+K+NIGHT++A+G AG+IK+VL++QHGVLPQ+LH + P+PH+ W A V ++ E Sbjct: 3550 LWLGSIKSNIGHTQAAAGVAGIIKMVLAMQHGVLPQTLHVDEPTPHVDWSAGEVTLLTEQ 3609 Query: 1955 VPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL 2014 W T R RRAGVSSFG +GTNAH ++E+AP P Sbjct: 3610 TAWPTVDRPRRAGVSSFGISGTNAHTIIEQAPAVEQLADGDATPATPALAL-----PLPY 3664 Query: 2015 ALSARSPEALVELARRYDDWLSAT----PGLDIADVCHTAGVGRSHFEYRAALVVDSVXX 2070 LSA+SPEAL A L AT PG D D+ + R+H E+RA L D Sbjct: 3665 VLSAKSPEALRAQASVLRTHLEATDHNGPGSD--DLAFSLATARAHLEHRAVLTADDPQE 3722 Query: 2071 XXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQC 2130 + G V TA+LFTGQGSQ GM REL++ PVFA + Sbjct: 3723 FREALARLADGDPSPRITTGA-VSDGRTAFLFTGQGSQRLGMGRELYEAYPVFADALDAV 3781 Query: 2131 AEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLG 2190 V L PL DVLF D A LL T++ QPALFAVE+ L RL +SW ++PD V G Sbjct: 3782 CAHVDAHLEVPLKDVLFGAD---AGLLDQTAYTQPALFAVEVALFRLVESWGVKPDFVAG 3838 Query: 2191 HSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRV 2250 HS+G+ AAA VAGVFSL D + L+ RGR+ +LP GG M+AV A + V + + RV Sbjct: 3839 HSIGEIAAAHVAGVFSLQDASELVFARGRLMQALPTGGVMIAVQASEDEVLPLLTD--RV 3896 Query: 2251 SVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXX 2309 S+ A NGP + V++G D I E F D + L SHAFHS +D +LD Sbjct: 3897 SIAAINGPQSVVIAGDEADAVAIAESFTDR--KSKRLTVSHAFHSPHMDGMLDAFREIAE 3954 Query: 2310 XXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIG 2369 +P+V N TGA+++ + A++W RH R+ V+F + +RT+ A G + +E+G Sbjct: 3955 GLSYEPSRIPVVSNLTGALVSDEMG-SAEFWVRHVREAVRFLDGIRTLEAAGVTKYVELG 4013 Query: 2370 PQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QP 2428 P VL+ A + + LRK + + ALASA+V G D+ A Sbjct: 4014 PDGVLSAMAQDCVSGEGSV--FIPVLRKARPEAESVTTALASAHVHGIPVDWQAYFAGTG 4071 Query: 2429 RRPVELPTYPFQRRRFWPKASSI------AVDGGTAASGILGSGKDLASGD-TIYTSRLS 2481 + V+LPTY FQR+R+WP A++ A+ G A +LG+ LA + ++T RLS Sbjct: 4072 AQRVDLPTYAFQRQRYWPSAAAFVTGDPTAIGLGDAGHPLLGAAVALADSEGVLFTGRLS 4131 Query: 2482 VKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQ 2538 + + PWLADH I G+V++PG + +A+ A VG ++++ P+++P++ ++Q Sbjct: 4132 LDTHPWLADHTILGSVLLPGTAFVDLAIRAGDQVGCDV-VEELTLEAPLVVPQRGGVQLQ 4190 Query: 2539 LTLHPADGGSVLSFQIHSR---PYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEV 2595 L + G F +HSR Y E W +A G + + S + + + Sbjct: 4191 LVVEAPSGPGQRPFSVHSRRQDAYAEE--PWMRHASGVLTSGVSRRELSVEGGE------ 4242 Query: 2596 IERLERMRP--------QDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELA 2647 E L P + L+E A+ +A+GP + G LK+ W DGE ++ + E Sbjct: 4243 FEALAVWPPTGAVPVDVRGLYEELAEAGVAYGPLFQG-LKAAWRRDGELFTEVALPGEAR 4301 Query: 2648 EQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRA 2707 + +HP L+D E + LP + V+L R Sbjct: 4302 REAARFGLHPALLD----AGLHAIGHGEGPEPAMTGALLPFSWAGVSLYAAGASSLRMRL 4357 Query: 2708 RWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWH 2767 H + L D GR + + ++ A + +R G L+ + W Sbjct: 4358 TPH---TPDDAHTMALLVADETGRPVAAVESLILRTASADQ-VRAADGGHLDSLFKVEWL 4413 Query: 2768 EVP--PPPSADDAVGTWLIAGFDELAAKVPGCV-PIDRNTDLQVLGEVLSQAHARGAGFS 2824 V P D W + G D L G + D LG L A G Sbjct: 4414 PVAGGATPHGDSTGRRWAVLGRDGLGLPATGVQGQVAEYDDASALGAAL----AAGEPVP 4469 Query: 2825 GVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACE 2884 V+ PG +T+ LS V L +T VA E Sbjct: 4470 DAVF--VHPGALPGQDTDTTAASVHAAVTDALSFVQEWLADERFAATRLVWLTSGAVADE 4527 Query: 2885 SGEPV-DPVQAALWGFGRTTINEEPALHCRL-VDCDGSSEAVDXXXXXXXXPGIQEPEIA 2942 G V D +A+ G R+ +E P L +D D +S A EPE+A Sbjct: 4528 PGAGVRDLAGSAVRGLLRSAQSENPGQLLMLDLDQDPASLAA-----LPAALAAGEPELA 4582 Query: 2943 VRQGKLLASRL 2953 +R+G+L RL Sbjct: 4583 IRRGELRTPRL 4593 Score = 1557 bits (4032), Expect = 0.0 Identities = 1008/2510 (40%), Positives = 1355/2510 (53%), Gaps = 125/2510 (4%) Query: 2 VSAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDP 59 V ++ PI AI+G FPG S E W L+ G +AIS P R WD++ +DP Sbjct: 136 VGSDEPI------AIVGIGCHFPGGVQSPEALWNLVETGTDAISAFPTGRGWDLDALYDP 189 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 DP G R GF+ D FDA FFG+S RE MDPQ R+L+E +W A + +G+ P Sbjct: 190 DPDRAGTSYAREGGFLHDADAFDAAFFGISPREALAMDPQQRLLLEASWEAFDRAGVDPA 249 Query: 120 SLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVA 179 +L GVFVG T +Y D E Y+ G + + A+GRI+Y G +GP V Sbjct: 250 ALRGGQVGVFVGAETQEYGPRLQDATD--GFEGYLVTGNAASVASGRIAYTFGFEGPTVT 307 Query: 180 VDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFD 239 VDTACSSSL A+H A QALR EC LALAGG V+ +P + ++FS LAPDGRCK F Sbjct: 308 VDTACSSSLAALHLAVQALRTGECSLALAGGVAVMASPGSFVSFSRQRGLAPDGRCKPFA 367 Query: 240 AAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI 299 AAADG GEG G+++V+RL DA G RI AV+RGSAINQDGAS GLT P+G +QQRVI Sbjct: 368 AAADGTAWGEGVGMLLVERLSDARAKGHRILAVVRGSAINQDGASNGLTAPSGPSQQRVI 427 Query: 300 ADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGH 359 AL AGL A+V +EAHGTGT LGDPIEAQA G + PL +GS K+NIGH Sbjct: 428 RQALANAGLSAAEVDVVEAHGTGTRLGDPIEAQALLATYGQEHTDDRPLWLGSLKSNIGH 487 Query: 360 LEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIA 419 + + + LP+ L+ + P+PH+ WE + ++ E V W + +PR A Sbjct: 488 TQAAAGVAGIIKMIMAMRHGVLPRTLHVDAPTPHVDWEAGAVTLLTEAVEWPESDRPRRA 547 Query: 420 GVSSFGFAGTNAHVILEE--------APAVGTPATTEPVEDPRRYSVLP------LSART 465 GVSSFG +GTNAHVI+EE AP G A + S P LSA+T Sbjct: 548 GVSSFGMSGTNAHVIVEEPAAQDREGAPTSGAQAPDSSQGQAQGTSTAPVLLPWALSAKT 607 Query: 466 PEALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALAD 525 PEAL A + A P D+ H+ T R EQRA ++ + RE+ ++ L ALA+ Sbjct: 608 PEALRAQARRLGTLIAAQPHVTPLDIGHSLATTRGRFEQRAIVLGDDREAFLDALHALAE 667 Query: 526 DRPAPGLVRGESHEAP-KTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILE 584 P +V+G + AP K A+LFTGQGSQ GM REL++T PVFA+ + + D LE Sbjct: 668 GNDTPSVVQGAA--APGKLAFLFTGQGSQRLGMGRELYETHPVFADALDDACWYLDDQLE 725 Query: 585 KPLLDVIFDADELDGDTESPLRH-TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQ 643 PLLDV+F ADE G E+ L H T Y QPALFAVE+ L RL SWG +PD V GHS+G+ Sbjct: 726 LPLLDVLF-ADE--GSPEAALLHQTAYTQPALFAVEVALFRLVDSWGLKPDFVAGHSIGE 782 Query: 644 YSAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAA 702 +AA VAGVF +ED L+A RGRL +LPAGG M A+ + + LTD +S+AA Sbjct: 783 IAAAHVAGVFSLEDACMLVAARGRLMQALPAGGVMIALQASEDEVLPLLTDR---VSIAA 839 Query: 703 YNGANTVLSGPAKDLESAVA-TLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEY 761 NG V+ +D +A+A T A G + L SHAFHS +D +L++F AQ L+Y Sbjct: 840 INGPQAVVIAGDEDAAAAIAETFQAAGRKTKRLTVSHAFHSPHMDAMLEEFLRVAQVLDY 899 Query: 762 REPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPV 821 +P ++ TG+ + AYW RH R V + VRTL R LE+GP V Sbjct: 900 AKPTLPVVSLLTGTTATPAELATPAYWVRHVRDAVRYLDGVRTLHQRGVRTFLELGPDAV 959 Query: 822 LTATAL-AAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARK 879 LTA A P A L S RP A + AVA A+ G D+ A F A++ Sbjct: 960 LTAMAQDCVDPQGAAFAPALRSGRPEAA---TVLNAVAHAHVRGAETDWAAFFAGTGAQR 1016 Query: 880 LDLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGET 939 +DLPTY F+ +++W + G P +E + LAA ++ + Sbjct: 1017 VDLPTYAFQRQRYWMDSRTPAPDSAAQRAHGGADPVDRVFWDAVEHEDVATLAAALELDL 1076 Query: 940 VDEQTLRVLNKLAARHNQQRSTHVDPDA-RYEIRWDXXXXXXXXXXXXXDWILV-----G 993 EQ L + + ++R T + D RY + W W+++ Sbjct: 1077 DGEQPLSEVVPALSAWRRRRRTQSEVDGWRYRVTW-KPLTEVSTSGLSGSWVVISPAGGA 1135 Query: 994 DDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAA 1053 DD+A V + + G ++V G D R+A AG L V G+ + Sbjct: 1136 DDSAVV---SALVGRGVDVRRVVVEAGVD----------RSALAGLLAEV------GSPS 1176 Query: 1054 PMRDLLRV-QHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGF 1111 + LL + + L G L +A DA + +P+W +TR V +D +V P Q+ +WG Sbjct: 1177 GVVSLLGLDESGGLLGTVGLVQALGDAGVGAPLWCLTRGAVSVGRSDRLVSPVQAQVWGL 1236 Query: 1112 GRAAALELPHIWGGLADLSGADTEWPRLIARITS--PRDGEDQIALRGDAVYAPRLVRR- 1168 GR AALE+P WGGL DL E R ++R+ GEDQ+A+R V+ RLVR Sbjct: 1237 GRVAALEVPEWWGGLIDLPEVLDE--RAVSRLVGVLAGSGEDQVAVRSSGVFGRRLVRAP 1294 Query: 1169 TGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRRE-PXXXXXXXXX 1227 E + P T LVTGG G +G VA +LA GA +VLTSRR Sbjct: 1295 RAEGASAWSPT---GTVLVTGGTGVLGGRVARWLAGAGAERLVLTSRRGLDAPGAVELVE 1351 Query: 1228 XXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEV 1287 + +V V+ D AD D R + ++AE L +VH AG + L L + Sbjct: 1352 ELTTGFGVEVSVVACDAAD-RDALRAL--LSAEAGSLTAVVHTAGVLDDGVLDALTPDRI 1408 Query: 1288 DRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRL 1347 D V K A +L E +L +L FV SS+ G GQ Y AANAFLD LA + Sbjct: 1409 DSVVRAKAVSALNLHELTAELGIELSDFVLFSSVTGTVGAAGQANYAAANAFLDALAEQR 1468 Query: 1348 RERGVTAVSVNFGPWAAG--MADAESRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVV 1404 R G+ A S+ +GPWA G AD AR+ + G+ ++P A++ + V AG V Sbjct: 1469 RADGLAATSIAWGPWAEGGMAADEAMDARMRREGMPPMAPTSAMSALEQAVGAGETALTV 1528 Query: 1405 AKIDWSRFLPLYQQAGRRAFL------SELESELXXXXXXXXXXXXXXXXXXLVEQLTKA 1458 A IDW RF + + +E + + LT+A Sbjct: 1529 ADIDWERFSSVIAAVRPNPLIGDFVVGAEGTAAASGHGSVVTGADVAATVSGRLAGLTQA 1588 Query: 1459 PVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIP 1518 +Q + L++ + A + +D + E F +LG DSL +VELR R+ +P Sbjct: 1589 --EQERELLSLVRLHVAAVLGHDGSDAVGAERAFKELGFDSLTSVELRNRLGAATDLRLP 1646 Query: 1519 VTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTV-TARTDDPIAVVAVSCRFP-GAPD 1576 TLV D+P + A+YL E+ G + + V +A DDPI +V++SCRFP G Sbjct: 1647 TTLVYDYPTSAALAEYLRGELAGSAQDAGPPLPAVVGSAADDDPIVIVSMSCRFPGGVRT 1706 Query: 1577 PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFG 1635 PE W+LLA G D + P DR WD+D Y DP+ G +YTR +FFG Sbjct: 1707 PEDLWQLLADGTDTVAAFPADRGWDLDGLYSADPERSGTSYTREGGFLYDAADFDADFFG 1766 Query: 1636 ISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAE--S 1693 ISPREA+ ++PQQRL+LET WE ERAG P+ LRGS+ GVF G +Y L++ E Sbjct: 1767 ISPREALAMDPQQRLLLETAWETFERAGIDPASLRGSQAGVFVGTNGQDYLSLVTREGDG 1826 Query: 1694 IDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLA 1753 +D +E H TGNA + +SGR+++ G EGPA+ VDTACSS+LVA+H A QAL+ G+C LA Sbjct: 1827 LDGLEGHVGTGNAASVVSGRLSYVFGLEGPAITVDTACSSSLVALHLAVQALRQGECTLA 1886 Query: 1754 LAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDG 1813 LAGGV V+ +P V SR R L+ GR K F ++ADG EG G+L+++RLSDA R+G Sbjct: 1887 LAGGVTVMSTPDAFVDFSRQRGLAEDGRIKAFASAADGTGWGEGVGMLLVERLSDARRNG 1946 Query: 1814 DRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLG 1873 V AV+ S++NQDGAS+GLT PNG +QQR+I LA AGLS ADVD +EAHGTGT LG Sbjct: 1947 HPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALAGAGLSAADVDAVEAHGTGTRLG 2006 Query: 1874 DPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLH 1933 DPIE Q PL +GSVK+NIGHT++A+G AG++K+V++++HGVLP++LH Sbjct: 2007 DPIEAQALLATYGQGRPADRPLWLGSVKSNIGHTQAAAGVAGVMKMVMAMRHGVLPRTLH 2066 Query: 1934 FENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXX 1993 + P+PH+ W A V ++ E W G RRAGVSSFG +GTNAH ++EEAP Sbjct: 2067 VDGPTPHVDWSAGDVALLTEQREWPATGHPRRAGVSSFGLSGTNAHTIIEEAPAD----- 2121 Query: 1994 XXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVG 2053 GT S L +SA+S L + + L P + I D+ ++ G Sbjct: 2122 ---DDAEPTTGAGTAPSVLPLLISAKSDAGLRAQSEQLATHLVGNPDVPIGDIAYSLTTG 2178 Query: 2054 RSHFEYRAALV--VDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPG 2111 RS E RA LV D+ G+V+G V A+LFTGQGSQ G Sbjct: 2179 RSGLETRAILVGDADNRTGLAAALRSLAAGEQAPGLVQGT-VTEGGLAFLFTGQGSQRLG 2237 Query: 2112 MARELFDTQPVFAQTV-RQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAV 2170 M REL++T PVFA + CA ++ PL DVLF A LL T++ QPALFAV Sbjct: 2238 MGRELYETYPVFADALDAVCARMDLEV---PLRDVLFGA---YAGLLDETAYTQPALFAV 2291 Query: 2171 EMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRM 2230 E+ L RL +SW + PD V GHS+G+ AAA VAGV SLDD L+ RGR+ G+LP GG M Sbjct: 2292 EVALFRLVESWGLRPDFVAGHSIGEIAAAHVAGVLSLDDACALVEARGRLMGALPGGGVM 2351 Query: 2231 VAVFADAEHVEQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATS 2289 +AV A V + E RVS+ A NGP + V++G D IVE F G + L S Sbjct: 2352 IAVQAPEAEVLPLLTE--RVSIAAINGPQSVVIAGDEADAVAIVESF--TGRKSKRLTVS 2407 Query: 2290 HAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQ 2349 HAFHS +D +L+ P +P+V N TGA+++ + A++W RH R+ V+ Sbjct: 2408 HAFHSPHMDGMLEDFRAVAEGLSYEAPRIPVVSNLTGALVSDEMG-SAEFWVRHVREAVR 2466 Query: 2350 FAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADAL 2409 F + +R + A G + +E+GP VL+ A + AA V LR G + AL Sbjct: 2467 FLDGMRVLEAAGVTTYVELGPGGVLSALAQECVSGDGAA--FVPVLRSGRPEAETAVTAL 2524 Query: 2410 ASAYVGGHRPDFAAVHRQPR-RPVELPTYPFQRRRFWP-KASSIAVDGGT 2457 A A+V G D+AA + V+LPTY FQR+RFWP + A GGT Sbjct: 2525 AQAHVRGVDVDWAAFFSGTGVQRVDLPTYAFQRQRFWPAMTAESAPVGGT 2574 Score = 1554 bits (4023), Expect = 0.0 Identities = 1008/2483 (40%), Positives = 1346/2483 (54%), Gaps = 122/2483 (4%) Query: 2 VSAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDP 59 V+ E PI I+G RFPG S E+ W L+ G + I+ P DR W++E + P Sbjct: 5002 VTGEDPI------VIVGMGCRFPGGVRSPEDLWQLVATGGDGITGFPSDRGWNVEALYHP 5055 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 DP G TR GF+ D FD FFG+S RE MDPQ R+L+ET+W A E +GI P Sbjct: 5056 DPDHAGTSYTREGGFLHDAADFDPGFFGISPREALAMDPQQRLLLETSWEAFERAGIDPA 5115 Query: 120 SLANSNTGVFVGLATHDY---LGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQG 175 +L S TGVF G+ HDY +G + PE +E Y+ G + + A+GRI+Y GL+G Sbjct: 5116 TLRGSRTGVFAGVMYHDYVTGIGDGGSAVELPEGVEGYLGTGNAGSIASGRIAYTFGLEG 5175 Query: 176 PAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRC 235 PAV VDTACSSSLVA+H A QALR EC +ALAGG V+ TP T + FS L+ DGRC Sbjct: 5176 PAVTVDTACSSSLVALHWAIQALRSGECTMALAGGVAVMATPETFVDFSRQRGLSADGRC 5235 Query: 236 KTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQ 295 K+F AAADG EG G+++V+RL DA R+G + AV+RGSAINQDGAS GLT PNG +Q Sbjct: 5236 KSFAAAADGTGWAEGAGMLLVERLSDAERNGHPVLAVVRGSAINQDGASNGLTAPNGPSQ 5295 Query: 296 QRVIADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKT 355 QRVI +AL A L AD+ +EAHGTGT LGDPIEAQA G R PL +GS K+ Sbjct: 5296 QRVIREALASADLSAADIDAVEAHGTGTRLGDPIEAQALLATYGREREAGRPLWLGSIKS 5355 Query: 356 NIGHLEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGK 415 NIGH + + + LP+ L+ + PSP + WE + ++ +PW + G+ Sbjct: 5356 NIGHTQAAAGVAGIIKMVMAMRHGVLPQTLHVDEPSPQVDWEAGEVSLLTGAMPWPQTGR 5415 Query: 416 PRIAGVSSFGFAGTNAHVILEEAPA---VGTPATTEPVEDPRRYSVLP--LSARTPEALV 470 PR AGVSSFG +GTNAH I+E+ P T V V+P LS + EAL Sbjct: 5416 PRRAGVSSFGISGTNAHTIIEQPPTREVTPTVPVAPVVPTVPTVPVVPWVLSGKGEEALR 5475 Query: 471 RLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAP 530 A + + ++ P+ R D++ + RA E RAA+V RE + L ALAD A Sbjct: 5476 AQARQLQSYVLRAPELRPVDIAGSLAVGRASFEDRAAVVAADREGLLAALAALADGGSAT 5535 Query: 531 GLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDV 590 G V G S K A+LFTGQGSQ GM REL++ PVFAE + +AV LE PL DV Sbjct: 5536 GAVEG-SAVGGKLAFLFTGQGSQRLGMGRELYEAYPVFAEAL----DAVCARLELPLKDV 5590 Query: 591 IFDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVA 650 +F AD L T Y QPALFAVE+ L RL +SWG PD V GHS+G+ +AA VA Sbjct: 5591 LFGADA------GLLDETAYTQPALFAVEVALFRLVESWGLRPDFVAGHSIGEIAAAHVA 5644 Query: 651 GVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTV 709 GVF ++D L+ RGRL G+LPAGG M AV + + LTD +S+AA NG +V Sbjct: 5645 GVFSLDDACALVEARGRLMGALPAGGVMIAVQASEDEVLPLLTDR---VSIAAINGPRSV 5701 Query: 710 LSGPAKDLESAVATLVA-DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRIL 768 + A D AVA + + G + L SHAFHS +D +L+DF + A+ L Y P+ + Sbjct: 5702 VI--AGDEADAVAIVESFTGRKSKRLTVSHAFHSPHMDGMLEDFRAVAEGLSYEAPRIPV 5759 Query: 769 IDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALA 828 + N TG+ L +W RH R+ V F +R L +E+GP VL+A A Sbjct: 5760 VSNLTGT-LVTDEMGSAEFWVRHVREAVRFLDGIRALEAAGVTTYVELGPGGVLSALAQE 5818 Query: 829 AWP-DPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAF-RQPDARKLDLPTYP 886 D A VL S R ++ A+A A+ G D+ AF A ++DLPTY Sbjct: 5819 CVSGDGAAFVPVLRSGR---SEAETAVTALAQAHVRGVNVDWAAFFAGTGAERVDLPTYA 5875 Query: 887 FEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTL- 945 F+ +++W I R Q+ A V AV E +E LA+ ++ VD+++ Sbjct: 5876 FQRQRYWLH----IPRVAQSGVADEVDARFWDAV---EREDLESLASTLE---VDDESAW 5925 Query: 946 -RVLNKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVG-----DDTAAV 999 VL L+A ++R+ RY + W W+++ DD+A V Sbjct: 5926 SSVLPALSAWRRERRAQSEVDGWRYRVSWKPLAEVSASGLSG-SWVVISPAGSVDDSAVV 5984 Query: 1000 LEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLL 1059 + + G ++V G D R+A AG L A G+AA + LL Sbjct: 5985 ---SALVGRGAEVRRVVVEAGVD----------RSALAGLL------ADAGSAAGVVSLL 6025 Query: 1060 RV-QHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAAL 1117 + + L G L +A DA + +P+W +TR V +D +V P Q+ +WG GR AAL Sbjct: 6026 GLDESEGLLGTVGLVQALGDAGVEAPLWCLTRGAVSVGRSDRLVSPVQAQVWGLGRVAAL 6085 Query: 1118 ELPHIWGGLADLSGADTEWPRLIARITS--PRDGEDQIALRGDAVYAPRLVRRT---GEP 1172 E+P WGGL DL E R +AR+ GEDQ+A+R V+ RLVR G Sbjct: 6086 EVPERWGGLVDLPEVLDE--RAVARLVGVLAGSGEDQVAVRSSGVFGRRLVRAPRAEGAS 6143 Query: 1173 SDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQ 1232 + TP T LVTGG G +G VA +LA GA +VLTSRR P Sbjct: 6144 AWTPTG-----TVLVTGGTGVLGGRVARWLAGAGAERLVLTSRRGPDAPGAAELVEELTT 6198 Query: 1233 -YACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVF 1291 + +V V+ D AD L T ++AE L ++H AG + L L +D V Sbjct: 6199 GFGVEVSVVACDAADRD---ALRTLLSAEAGTLTAVIHTAGVLDDGVLDALTPDRIDSVL 6255 Query: 1292 AGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERG 1351 K A++L E +L +L FV SS++ G GQ Y AANA+LD LA + R G Sbjct: 6256 RAKAVSAFNLHELTAELGIELSAFVLFSSMSGTVGAAGQANYAAANAYLDALAEQRRADG 6315 Query: 1352 VTAVSVNFGPWAAG--MADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKID 1408 + A S+ +GPWA G D AR+ + G+ ++P AL + V + V ++ Sbjct: 6316 LAATSLAWGPWAEGGMAGDDAMDARMRREGLPPMAPDAALTLLRQSVGSADAALMVVDVE 6375 Query: 1409 WSRFLPLYQQAGRRAFLSEL-ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLI 1467 W RF P L+EL E+ E+L ++ + Sbjct: 6376 WQRFAPALTVVRPSNLLAELPEARPAGTDSRTGGATSSEGAGSFAERLAALGGAEQDKEL 6435 Query: 1468 TNYLRNAVAEVTRVDADE-IRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHP 1526 N +R +A V E + E F +LG DSL AVELR R+ G +P TL+ D+P Sbjct: 6436 LNLVRTHIAAVLGHGGSEAVGAERAFKELGFDSLTAVELRNRLGAATGVRLPATLIFDYP 6495 Query: 1527 RLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLA 1585 + A YL E+LG + ++ V DDPIA+VA+SCRFPG PE W LL+ Sbjct: 6496 TATALAAYLRGELLGTQVVVSGPVSNGVVV-DDDPIAIVAMSCRFPGGVRTPEDLWRLLS 6554 Query: 1586 GGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWI 1644 G DAI E P DR WD+ Y PDPD G Y R +FFGISPREA+ + Sbjct: 6555 TGGDAIGEFPADRGWDLSRLYSPDPDKQGTFYARAGGFLYDAADFDADFFGISPREALAM 6614 Query: 1645 EPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITG 1704 +PQQRL+LET WE ERAG PS LRGS+ GVF G +Y +L D IE TG Sbjct: 6615 DPQQRLLLETSWEAFERAGIDPSSLRGSQAGVFVGTNGQDYGAMLQTIP-DGIEGFLGTG 6673 Query: 1705 NALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSP 1764 NA + +SGR+++A G EGPAV VDTACS++LVA+H A QAL+SG+C LALAGGV V+ SP Sbjct: 6674 NAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAVQALRSGECSLALAGGVTVMSSP 6733 Query: 1765 VTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASS 1824 + SR R L+ GR K F A+ADG EG G+L+++RLSDA R+G V A++ S+ Sbjct: 6734 GAYIDFSRQRGLAEDGRIKAFAAAADGTGWGEGVGMLLVERLSDARRNGHPVLALVRGSA 6793 Query: 1825 VNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXX 1884 +NQDGAS+GLT PNG +QQR+I LA AGLS A+VD +EAHGTGT LGDPIEVQ Sbjct: 6794 INQDGASNGLTAPNGPSQQRVIRQALANAGLSAAEVDAVEAHGTGTRLGDPIEVQALLAT 6853 Query: 1885 XXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWD 1944 PL +GS+K+NIGHT++A+G AG+IK+VL+++HGVLPQ+LH + P+PH+ W Sbjct: 6854 YGREREADQPLWLGSIKSNIGHTQAAAGVAGVIKMVLAMEHGVLPQTLHVDEPTPHVDWS 6913 Query: 1945 ALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXX 2004 A V ++ + V W GR RRAGVSSFGF+GTNAH ++E+AP Sbjct: 6914 AGDVALLTDAVEWPETGRPRRAGVSSFGFSGTNAHTVLEQAPKPEEPEESQQPEETNAPA 6973 Query: 2005 XGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALV 2064 LSA+S AL A R +++ P L DV ++ R+ E RA +V Sbjct: 6974 RPHQSGVMPWTLSAKSEAALRVQAERLRTRIASDPLLQPVDVAYSLATSRAALERRAVVV 7033 Query: 2065 VDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFA 2124 G+V+G V A+LFTGQGSQ GM REL++T PVFA Sbjct: 7034 ATERDEFLAGLKALASGQPAPGLVQG-RVTEGGLAFLFTGQGSQRLGMGRELYETYPVFA 7092 Query: 2125 QTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIE 2184 + +AV L PL+DVLF T+R D L T + QPALFAVE+ L RL +SW + Sbjct: 7093 DAL----DAVCVRLELPLMDVLFGTER---DALDETGYTQPALFAVEVALFRLVESWGVR 7145 Query: 2185 PDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVA 2244 PD + GHS+G+ AAA VAGVFSLDD L+ RGR+ +LP GG M+AV A V + Sbjct: 7146 PDFLAGHSIGEIAAAHVAGVFSLDDACALVEARGRLMQALPTGGVMIAVQASEAEVLPLL 7205 Query: 2245 GEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDX 2303 E RVS+ A NGP + V++G D +VE F G + L SHAFHS +D +L Sbjct: 7206 TE--RVSIAAINGPQSVVIAGDEADAVALVESF--TGRKSKRLTVSHAFHSPHMDGMLAD 7261 Query: 2304 XXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCS 2363 P +P+V N TGA++T + A +W RH R+ V+F + RT+ ALG + Sbjct: 7262 FRKVAEGLSYEAPRIPVVSNLTGALVTDEMG-SADFWVRHVREAVRFLDGTRTLEALGVT 7320 Query: 2364 VLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAA 2423 +E+GP VL+ A + + V LR G + + ALA +V G D+ A Sbjct: 7321 TYVELGPDGVLSAMAQECVTGEDSV--FVPVLRSGRPEAESVTTALAQVHVRGIAVDWQA 7378 Query: 2424 VHR-QPRRPVELPTYPFQRRRFW 2445 + V+LPTY FQRRR+W Sbjct: 7379 YFAGTGAQRVDLPTYAFQRRRYW 7401 Score = 899 bits (2324), Expect = 0.0 Identities = 609/1574 (38%), Positives = 829/1574 (52%), Gaps = 83/1574 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + RFPG + E+ W LL G +AI + P DR WD+ + PDP G R Sbjct: 6531 AIVAMSCRFPGGVRTPEDLWRLLSTGGDAIGEFPADRGWDLSRLYSPDPDKQGTFYARAG 6590 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE MDPQ R+L+ET+W A E +GI P+SL S GVFVG Sbjct: 6591 GFLYDAADFDADFFGISPREALAMDPQQRLLLETSWEAFERAGIDPSSLRGSQAGVFVGT 6650 Query: 133 ATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 DY M T P+ IE ++ G + + +GR+SY GL+GPAV VDTACS+SLVA+ Sbjct: 6651 NGQDYGAMLQ---TIPDGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSASLVAL 6707 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR EC LALAGG V+ +P I FS LA DGR K F AAADG GEG Sbjct: 6708 HWAVQALRSGECSLALAGGVTVMSSPGAYIDFSRQRGLAEDGRIKAFAAAADGTGWGEGV 6767 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 G+++V+RL DA R+G + A++RGSAINQDGAS GLT PNG +QQRVI AL AGL A Sbjct: 6768 GMLLVERLSDARRNGHPVLALVRGSAINQDGASNGLTAPNGPSQQRVIRQALANAGLSAA 6827 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 +V +EAHGTGT LGDPIE QA G R ++PL +GS K+NIGH + Sbjct: 6828 EVDAVEAHGTGTRLGDPIEVQALLATYGREREADQPLWLGSIKSNIGHTQAAAGVAGVIK 6887 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 +E+ LP+ L+ + P+PH+ W + ++ + V W G+PR AGVSSFGF+GTNA Sbjct: 6888 MVLAMEHGVLPQTLHVDEPTPHVDWSAGDVALLTDAVEWPETGRPRRAGVSSFGFSGTNA 6947 Query: 432 HVILEEAPAVGTPATTEPVED------PRRYSVLP--LSARTPEALVRLAGEYRDWLRAH 483 H +LE+AP P ++ E+ P + V+P LSA++ AL A R + + Sbjct: 6948 HTVLEQAPKPEEPEESQQPEETNAPARPHQSGVMPWTLSAKSEAALRVQAERLRTRIASD 7007 Query: 484 PQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKT 543 P + DV+++ T+RA LE+RA +V R+ + L ALA +PAPGLV+G E Sbjct: 7008 PLLQPVDVAYSLATSRAALERRAVVVATERDEFLAGLKALASGQPAPGLVQGRVTEGG-L 7066 Query: 544 AWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTES 603 A+LFTGQGSQ GM REL++T PVFA+ + +AV LE PL+DV+F G Sbjct: 7067 AFLFTGQGSQRLGMGRELYETYPVFADAL----DAVCVRLELPLMDVLF------GTERD 7116 Query: 604 PLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIA 663 L T Y QPALFAVE+ L RL +SWG PD + GHS+G+ +AA VAGVF ++D L+ Sbjct: 7117 ALDETGYTQPALFAVEVALFRLVESWGVRPDFLAGHSIGEIAAAHVAGVFSLDDACALVE 7176 Query: 664 ERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVAT 723 RGRL +LP GG M AV + L E +S+AA NG +V+ A D AVA Sbjct: 7177 ARGRLMQALPTGGVMIAVQASEAEVLPLLTE--RVSIAAINGPQSVVI--AGDEADAVAL 7232 Query: 724 LVA-DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTR 782 + + G + L SHAFHS +D +L DF A+ L Y P+ ++ N TG AL Sbjct: 7233 VESFTGRKSKRLTVSHAFHSPHMDGMLADFRKVAEGLSYEAPRIPVVSNLTG-ALVTDEM 7291 Query: 783 LDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATA--LAAWPDPATTPQVL 840 +W RH R+ V F RTL + +E+GP VL+A A D P VL Sbjct: 7292 GSADFWVRHVREAVRFLDGTRTLEALGVTTYVELGPDGVLSAMAQECVTGEDSVFVP-VL 7350 Query: 841 ASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDNRA 899 S RP + +T A+A + G D++A F A+++DLPTY F+ R++W + A Sbjct: 7351 RSGRP---EAESVTTALAQVHVRGIAVDWQAYFAGTGAQRVDLPTYAFQRRRYWLEEAPA 7407 Query: 900 IDR-DTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLR-VLNKLAARHNQ 957 + T S G+V AV ++ + L A +D + +Q L +L L+A Q Sbjct: 7408 TAAVEPLTGSLGAVDAQFWAAV---DNADLSALTATLDIDVDADQPLSALLPALSAWRRQ 7464 Query: 958 QRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAV--LEFADALTAGGHRHQI 1015 ++ V RY + W W++V T+ V + AL A G + Sbjct: 7465 RQEQSVVDGWRYTVTWKPMADPAVARPTGT-WLVVTPATSLVDLPAVSAALAAQGVDVRE 7523 Query: 1016 VALPGSDADEAQLVDTLRAASAGE-----LYVVHIAAGDGAAAPMRDLLRVQHRTLGGLR 1070 VAL ++ D + +R A AG+ L ++ +A A P + TL Sbjct: 7524 VALEAAELDRDGVAGRMREALAGDRADGVLSLLALAEHPHPAHPAAPTGLLLTGTL---- 7579 Query: 1071 RLFRAANDAELRSPIWLVTRDGQRVTDTDTV-VPEQSCLWGFGRAAALELPHIWGGLADL 1129 +A DA + +P+W +T +D + Q+ +WG GR ALE P WGGL DL Sbjct: 7580 --VQALGDAGVDAPLWCLTTGAVATAPSDLIGSAAQAQVWGLGRVVALEHPERWGGLVDL 7637 Query: 1130 SGADTE--WPRLIARITSPRDGEDQIALRGDAVYAPRLVRRT----GEPSDTPLPV---- 1179 E RL+A + D EDQIA+R + A R+ G+ +D+ Sbjct: 7638 PVPADERALDRLLAVLAGAGD-EDQIAVRSAGLLARRIGHAAPPAAGQHADSGTSGAGAA 7696 Query: 1180 -----REDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYA 1234 R T LVTGG GA+G VA +LA+HGA H+VL SRR P Sbjct: 7697 AGSAWRPRGTVLVTGGTGALGGHVARWLAAHGAEHLVLLSRRGPQAPGADALVAEIAALG 7756 Query: 1235 CDVRVITADVADAHDVARLMTTVAAEL--PPLAGIVHAAGEIGTTPLSGLDDAEVDRVFA 1292 + DV D V+ L+ +A P L + H AG PL G EV V A Sbjct: 7757 AGATAVACDVTDRTAVSELLAGLADGTYGPGLTAVFHTAGAGQFAPLDGTGPGEVAEVVA 7816 Query: 1293 GKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGV 1352 KV GA HL E L D T+LD FV SSIA VWG GQ+AY AANA LD LA + R RG+ Sbjct: 7817 AKVAGAAHLDELLGD--TELDAFVLFSSIAGVWGSGGQSAYAAANAHLDALAQQRRARGL 7874 Query: 1353 TAVSVNFGPWAAG--MADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDW 1409 TA SV +GPW G +AD E+ +L +RG+ ++P ++A + + G V VA +DW Sbjct: 7875 TATSVAWGPWGEGGLVADDEAAEQLRRRGLPVMAPELSIAALQQALDGDETAVTVADVDW 7934 Query: 1410 SRFLPLYQQAGRRAFLSEL-ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLIT 1468 F+P + A R +++L E L +L + + ++ Sbjct: 7935 DLFVPAFTAARPRPLITDLPEVRRALAAEQDGAATAAGEAAGLEAELRGMSGTEAEGVVL 7994 Query: 1469 NYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPR 1527 N +R VA V A + F +LG DSL AVELR R+ G +P +LV D+P Sbjct: 7995 NLVRTQVAVVLGHGGATAVEAARAFKELGFDSLTAVELRNRLSTATGLRLPASLVFDYPT 8054 Query: 1528 LSDAADYLLVEVLG 1541 + A ++ E+LG Sbjct: 8055 PAALAAHIRAELLG 8068 Score = 821 bits (2121), Expect = 0.0 Identities = 535/1338 (39%), Positives = 726/1338 (54%), Gaps = 53/1338 (3%) Query: 1149 GEDQIALRGDAVYAPRLVR-RTGEPSDTPLPVREDR--TYLVTGGLGAIGLEVAGYLAS- 1204 GE ++A+R + PRL R + + + PL D T LVTG G +G A +L + Sbjct: 4577 GEPELAIRRGELRTPRLTRVPSADAAAEPLGTLGDPSGTVLVTGATGTLGGLFARHLVTA 4636 Query: 1205 HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPL 1264 +G ++LTSRR P EQ V ++ D AD +A L+ V +E PL Sbjct: 4637 YGVRRLLLTSRRGPEAEGAAELVAELEQLGAHVELVACDAADRSALAALLGAVPSE-HPL 4695 Query: 1265 AGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASV 1324 +VH AG + LS L V V KV AW+L E +L L FV S A+ Sbjct: 4696 TAVVHTAGVLDDGILSSLTPERVAAVLRPKVDAAWNLHELTREL--GLSAFVLFSGAAAA 4753 Query: 1325 WGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA---AGMA---DAESRARLEQR 1378 +G GQ Y AAN+FL+ LA + R G+ A S+ +G WA GMA D R+ + Sbjct: 4754 FGAAGQGNYAAANSFLEALAEQRRAEGLPATSLAWGLWAPQTGGMAQQLDEVDLRRIARD 4813 Query: 1379 GVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXX 1438 GV LS E L G+ D V+ + + Q + L + + Sbjct: 4814 GVGGLSGDEGL-GLFDTAMTVDAAVLLPMRLDLAVARAQAVSTGETPALLRALIRVPARR 4872 Query: 1439 XXXXXXXXXXXX-LVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLG 1496 L +L+ P +R+ ++ + + VAEV DA + + F +LG Sbjct: 4873 AVEQRTAADGASPLAARLSALPDAEREDMLLDLVCGRVAEVLGHTDARAVDADRAFKELG 4932 Query: 1497 MDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTA 1556 DSL AVELR ++ G + TLV D+P A +LL E+ G + + + A Sbjct: 4933 FDSLTAVELRNVLKAATGLRLSPTLVFDYPTPVALARHLLAELAGTADDQDAVRGRKAPA 4992 Query: 1557 RT----------DDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEF 1604 R +DPI +V + CRFP G PE W+L+A G D I P DR W+++ Sbjct: 4993 RPATAAVTSVTGEDPIVIVGMGCRFPGGVRSPEDLWQLVATGGDGITGFPSDRGWNVEAL 5052 Query: 1605 YDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGY 1664 Y PDPD G +YTR P FFGISPREA+ ++PQQRL+LET WE ERAG Sbjct: 5053 YHPDPDHAGTSYTREGGFLHDAADFDPGFFGISPREALAMDPQQRLLLETSWEAFERAGI 5112 Query: 1665 APSDLRGSRTGVFTGVAANEYAHLL-----SAESIDKIEPHFITGNALNAISGRVAFALG 1719 P+ LRGSRTGVF GV ++Y + + E + +E + TGNA + SGR+A+ G Sbjct: 5113 DPATLRGSRTGVFAGVMYHDYVTGIGDGGSAVELPEGVEGYLGTGNAGSIASGRIAYTFG 5172 Query: 1720 FEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPV 1779 EGPAV VDTACSS+LVA+H A QAL+SG+C +ALAGGV V+ +P T V SR R LS Sbjct: 5173 LEGPAVTVDTACSSSLVALHWAIQALRSGECTMALAGGVAVMATPETFVDFSRQRGLSAD 5232 Query: 1780 GRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNG 1839 GRCK+F A+ADG +EG G+L+++RLSDA R+G V AV+ S++NQDGAS+GLT PNG Sbjct: 5233 GRCKSFAAAADGTGWAEGAGMLLVERLSDAERNGHPVLAVVRGSAINQDGASNGLTAPNG 5292 Query: 1840 GAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGS 1899 +QQR+I LA A LS AD+D +EAHGTGT LGDPIE Q PL +GS Sbjct: 5293 PSQQRVIREALASADLSAADIDAVEAHGTGTRLGDPIEAQALLATYGREREAGRPLWLGS 5352 Query: 1900 VKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT 1959 +K+NIGHT++A+G AG+IK+V++++HGVLPQ+LH + PSP + W+A V ++ +PW Sbjct: 5353 IKSNIGHTQAAAGVAGIIKMVMAMRHGVLPQTLHVDEPSPQVDWEAGEVSLLTGAMPWPQ 5412 Query: 1960 NGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSAR 2019 GR RRAGVSSFG +GTNAH ++E+ PP P V LS + Sbjct: 5413 TGRPRRAGVSSFGISGTNAHTIIEQ-PPTREVTPTVPVAPVVPTVPTVPVVPWV--LSGK 5469 Query: 2020 SPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXX 2079 EAL AR+ ++ P L D+ + VGR+ FE RAA+V Sbjct: 5470 GEEALRAQARQLQSYVLRAPELRPVDIAGSLAVGRASFEDRAAVVAADREGLLAALAALA 5529 Query: 2080 XXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLP 2139 + G V G V A+LFTGQGSQ GM REL++ PVFA+ + +AV L Sbjct: 5530 DGGSATGAVEGSAV-GGKLAFLFTGQGSQRLGMGRELYEAYPVFAEAL----DAVCARLE 5584 Query: 2140 RPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAA 2199 PL DVLF D A LL T++ QPALFAVE+ L RL +SW + PD V GHS+G+ AAA Sbjct: 5585 LPLKDVLFGAD---AGLLDETAYTQPALFAVEVALFRLVESWGLRPDFVAGHSIGEIAAA 5641 Query: 2200 CVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP- 2258 VAGVFSLDD L+ RGR+ G+LP GG M+AV A + V + + RVS+ A NGP Sbjct: 5642 HVAGVFSLDDACALVEARGRLMGALPAGGVMIAVQASEDEVLPLLTD--RVSIAAINGPR 5699 Query: 2259 NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTL 2318 + V++G D IVE F G + L SHAFHS +D +L+ P + Sbjct: 5700 SVVIAGDEADAVAIVESF--TGRKSKRLTVSHAFHSPHMDGMLEDFRAVAEGLSYEAPRI 5757 Query: 2319 PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAA 2378 P+V N TG ++T + A++W RH R+ V+F + +R + A G + +E+GP VL+ A Sbjct: 5758 PVVSNLTGTLVTDEMG-SAEFWVRHVREAVRFLDGIRALEAAGVTTYVELGPGGVLSALA 5816 Query: 2379 VQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTY 2437 + AA V LR G ++ ALA A+V G D+AA V+LPTY Sbjct: 5817 QECVSGDGAA--FVPVLRSGRSEAETAVTALAQAHVRGVNVDWAAFFAGTGAERVDLPTY 5874 Query: 2438 PFQRRRFWPKASSIAVDG 2455 FQR+R+W +A G Sbjct: 5875 AFQRQRYWLHIPRVAQSG 5892 Score = 741 bits (1913), Expect = 0.0 Identities = 436/1011 (43%), Positives = 579/1011 (57%), Gaps = 21/1011 (2%) Query: 1455 LTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVG 1514 LT+A +Q +L+ A A + D + F DLG DSL AV+L R+ G G Sbjct: 39 LTEA--EQHTALLEWVSSLASAALRDAAPDTLDPHRPFLDLGFDSLAAVDLHARLVAGTG 96 Query: 1515 KDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA 1574 +PVTL DHP + A +L +LGL T +D+PIA+V + C FPG Sbjct: 97 LRLPVTLAFDHPTPAHLARHLHAAILGLTGPAET--PVTAAVGSDEPIAIVGIGCHFPGG 154 Query: 1575 -PDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPE 1632 PE+ W L+ G DAI P R WD+D YDPDPD G +Y R Sbjct: 155 VQSPEALWNLVETGTDAISAFPTGRGWDLDALYDPDPDRAGTSYAREGGFLHDADAFDAA 214 Query: 1633 FFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAE 1692 FFGISPREA+ ++PQQRL+LE WE +RAG P+ LRG + GVF G EY L + Sbjct: 215 FFGISPREALAMDPQQRLLLEASWEAFDRAGVDPAALRGGQVGVFVGAETQEYGPRLQ-D 273 Query: 1693 SIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDL 1752 + D E + +TGNA + SGR+A+ GFEGP V VDTACSS+L A+H A QAL++G+C L Sbjct: 274 ATDGFEGYLVTGNAASVASGRIAYTFGFEGPTVTVDTACSSSLAALHLAVQALRTGECSL 333 Query: 1753 ALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRD 1812 ALAGGV V+ SP + V+ SR R L+P GRCK F A+ADG EG G+L+++RLSDA Sbjct: 334 ALAGGVAVMASPGSFVSFSRQRGLAPDGRCKPFAAAADGTAWGEGVGMLLVERLSDARAK 393 Query: 1813 GDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPL 1872 G R+ AV+ S++NQDGAS+GLT P+G +QQR+I LA AGLS A+VD +EAHGTGT L Sbjct: 394 GHRILAVVRGSAINQDGASNGLTAPSGPSQQRVIRQALANAGLSAAEVDVVEAHGTGTRL 453 Query: 1873 GDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSL 1932 GDPIE Q PL +GS+K+NIGHT++A+G AG+IK++++++HGVLP++L Sbjct: 454 GDPIEAQALLATYGQEHTDDRPLWLGSLKSNIGHTQAAAGVAGIIKMIMAMRHGVLPRTL 513 Query: 1933 HFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQ---- 1988 H + P+PH+ W+A V ++ E V W + R RRAGVSSFG +GTNAHV+VEE Q Sbjct: 514 HVDAPTPHVDWEAGAVTLLTEAVEWPESDRPRRAGVSSFGMSGTNAHVIVEEPAAQDREG 573 Query: 1989 LHXXXXXXXXXXXXXXXGTDDSPQVL--ALSARSPEALVELARRYDDWLSATPGLDIADV 2046 GT +P +L ALSA++PEAL ARR ++A P + D+ Sbjct: 574 APTSGAQAPDSSQGQAQGTSTAPVLLPWALSAKTPEALRAQARRLGTLIAAQPHVTPLDI 633 Query: 2047 CHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQG 2106 H+ R FE RA ++ D VV+G A+LFTGQG Sbjct: 634 GHSLATTRGRFEQRAIVLGDDREAFLDALHALAEGNDTPSVVQGA-AAPGKLAFLFTGQG 692 Query: 2107 SQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATD-RETADLLQHTSFAQP 2165 SQ GM REL++T PVFA + + D L PLLDVLFA + A LL T++ QP Sbjct: 693 SQRLGMGRELYETHPVFADALDDACWYLDDQLELPLLDVLFADEGSPEAALLHQTAYTQP 752 Query: 2166 ALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLP 2225 ALFAVE+ L RL SW ++PD V GHS+G+ AAA VAGVFSL+D L+A RGR+ +LP Sbjct: 753 ALFAVEVALFRLVDSWGLKPDFVAGHSIGEIAAAHVAGVFSLEDACMLVAARGRLMQALP 812 Query: 2226 EGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGED-LEEIVERFEDEGIRCT 2284 GG M+A+ A + V + + RVS+ A NGP V+ ED I E F+ G + Sbjct: 813 AGGVMIALQASEDEVLPLLTD--RVSIAAINGPQAVVIAGDEDAAAAIAETFQAAGRKTK 870 Query: 2285 WLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHS 2344 L SHAFHS +D +L+ PTLP+V TG T YW RH Sbjct: 871 RLTVSHAFHSPHMDAMLEEFLRVAQVLDYAKPTLPVVSLLTGTTATPAELATPAYWVRHV 930 Query: 2345 RQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQ 2404 R V++ + VRT+ G +E+GP VLT A AA +LR G + Sbjct: 931 RDAVRYLDGVRTLHQRGVRTFLELGPDAVLTAMAQDCVDPQGAA--FAPALRSGRPEAAT 988 Query: 2405 IADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSIAVD 2454 + +A+A A+V G D+AA + V+LPTY FQR+R+W + + A D Sbjct: 989 VLNAVAHAHVRGAETDWAAFFAGTGAQRVDLPTYAFQRQRYWMDSRTPAPD 1039 Score = 181 bits (460), Expect = 1e-42 Identities = 127/362 (35%), Positives = 170/362 (46%), Gaps = 21/362 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHTYAADV 3356 L+TGG G +G A +LA GA +VLTSRR PD A ++E+T + A D Sbjct: 6152 LVTGGTGVLGGRVARWLAGAGAERLVLTSRRGPDAPGAAELVEELTTGFGVEVSVVACDA 6211 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXX 3414 D + LL+ AE L + H AGVLDD +L A P+R + L KA A H Sbjct: 6212 ADRDALRTLLS---AEAGTLTAVIHTAGVLDDGVLDALTPDRIDSVLRAKAVSAFNLHEL 6268 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQANYA ANA LD L +RRA GL AT + +GPW + Sbjct: 6269 TAELGIELSAFVLFSSMSGTVGAAGQANYAAANAYLDALAEQRRADGLAATSLAWGPWAE 6328 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 GGMA +A A + +GL P+ P AAL L + + + V+ WQR A L RP Sbjct: 6329 GGMAGDDAMDARMRREGLPPMAPDAALTLLRQSVGSADAALMVVDVEWQRFAPALTVVRP 6388 Query: 3535 PILDLVLPSA-----------AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLR 3583 L LP A A + G ++L + ++ + ++ + L Sbjct: 6389 SNLLAELPEARPAGTDSRTGGATSSEGAGSFAERLAALGGAEQDKELLNLVRTHIAAVLG 6448 Query: 3584 LASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 A A F +LG DSL A+ELRNRL + G + + AT +FDYPT LA YL G Sbjct: 6449 HGGSEAVGAERAFKELGFDSLTAVELRNRLGAATGVR--LPATLIFDYPTATALAAYLRG 6506 Query: 3642 QL 3643 +L Sbjct: 6507 EL 6508 Score = 181 bits (458), Expect = 3e-42 Identities = 126/364 (34%), Positives = 177/364 (48%), Gaps = 23/364 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHTYAADV 3356 L+TGG G +G A +LA GA +VLTSRR D A ++E+T + A D Sbjct: 1309 LVTGGTGVLGGRVARWLAGAGAERLVLTSRRGLDAPGAVELVEELTTGFGVEVSVVACDA 1368 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXX 3414 D + LL+ AE L + H AGVLDD +L A P+R + + KA A H Sbjct: 1369 ADRDALRALLS---AEAGSLTAVVHTAGVLDDGVLDALTPDRIDSVVRAKAVSALNLHEL 1425 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQANYA ANA LD L +RRA GL AT I +GPW + Sbjct: 1426 TAELGIELSDFVLFSSVTGTVGAAGQANYAAANAFLDALAEQRRADGLAATSIAWGPWAE 1485 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 GGMA+ EA A + +G+ P+ P++A+ AL + + G TV +W+R + V+ + RP Sbjct: 1486 GGMAADEAMDARMRREGMPPMAPTSAMSALEQAVGAGETALTVADIDWERFSSVIAAVRP 1545 Query: 3535 -PIL-DLVL---PSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL----- 3584 P++ D V+ +AA G + + AG +RE+ + +RL Sbjct: 1546 NPLIGDFVVGAEGTAAASGHGSVVTGADVAATVSGRLAGLTQAEQERELLSLVRLHVAAV 1605 Query: 3585 -----ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 + A F +LG DSL ++ELRNRL + + T V+DYPT LAEYL Sbjct: 1606 LGHDGSDAVGAERAFKELGFDSLTSVELRNRLGA--ATDLRLPTTLVYDYPTSAALAEYL 1663 Query: 3640 VGQL 3643 G+L Sbjct: 1664 RGEL 1667 Score = 154 bits (390), Expect = 2e-34 Identities = 118/362 (32%), Positives = 160/362 (44%), Gaps = 21/362 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG G +G A +LA GA +VLTSRR D + E + A D Sbjct: 2838 LVTGGTGVLGGRVARWLAGAGAERLVLTSRRGLDAPGTAELVEELTSSGVEVSVVACDAA 2897 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXXX 3415 D + LL+ +E L + H AGVLDD +L A P+R + KA A H Sbjct: 2898 DRDALRALLS---SEAGSLTAVIHTAGVLDDGVLDALTPDRIDGVVRAKAVSALNLHELT 2954 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQANYA ANA LD L +RRA GL AT I +GPW +G Sbjct: 2955 AELGIELSAFVLFSSMSGTVGTAGQANYAAANAYLDALAEQRRADGLAATSIAWGPWAEG 3014 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP 3535 GMA+ A A + G+ P+ A+ AL + +A TV W R +AR Sbjct: 3015 GMAADAALEARMRRDGVPPMPADPAIRALRQAVAGDDAVLTVADVEWDRFLPGFVAARHS 3074 Query: 3536 ILDLVL------------PSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLR 3583 L L AA A L +L ++ + + ++ +V L Sbjct: 3075 ELFSELRDVRDARAAQDRAQAAVAADRPDSLSGRLSAQAPAEQERELLDLVRTQVAAVLG 3134 Query: 3584 LASPP--AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 A A F +LG DSLMA+ELRNR+ S + + AT ++D+PT LAE+L G Sbjct: 3135 HAGVENVGAGRAFKELGFDSLMAVELRNRIGS--ATELRLPATLIYDHPTSAALAEFLRG 3192 Query: 3642 QL 3643 +L Sbjct: 3193 EL 3194 Score = 154 bits (388), Expect = 3e-34 Identities = 117/364 (32%), Positives = 162/364 (44%), Gaps = 23/364 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA GA +VL SRR P A+ A DV Sbjct: 7708 LVTGGTGALGGHVARWLAAHGAEHLVLLSRRGPQAPGADALVAEIAALGAGATAVACDVT 7767 Query: 3358 DEAQVADLLARIRAEL--PPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 D V++LLA + P L + H AG A L P +A K GA+H Sbjct: 7768 DRTAVSELLAGLADGTYGPGLTAVFHTAGAGQFAPLDGTGPGEVAEVVAAKVAGAAHLDE 7827 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQ+ YA ANA LD L +RRA+GL AT + +GPWG+G Sbjct: 7828 LLGDTELDAFVLFSSIAGVWGSGGQSAYAAANAHLDALAQQRRARGLTATSVAWGPWGEG 7887 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP 3535 G+ + + A + +GL + P ++ AL + + TV +W +ARP Sbjct: 7888 GLVADDEAAEQLRRRGLPVMAPELSIAALQQALDGDETAVTVADVDWDLFVPAFTAARPR 7947 Query: 3536 ILDLVLP--------------SAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNF 3581 L LP +AAGEA G L +L + + G V ++ +V Sbjct: 7948 PLITDLPEVRRALAAEQDGAATAAGEAAG---LEAELRGMSGTEAEGVVLNLVRTQVAVV 8004 Query: 3582 LRLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 L A A+ F +LG DSL A+ELRNRL + G + A+ VFDYPT LA ++ Sbjct: 8005 LGHGGATAVEAARAFKELGFDSLTAVELRNRLSTATG--LRLPASLVFDYPTPAALAAHI 8062 Query: 3640 VGQL 3643 +L Sbjct: 8063 RAEL 8066 Score = 125 bits (314), Expect = 1e-25 Identities = 114/363 (31%), Positives = 157/363 (43%), Gaps = 21/363 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPD-ESAQRAIDEITERHKCRIHTYAAD 3355 L+TG G +G A +L G ++LTSRR P+ E A + E+ E+ + A D Sbjct: 4617 LVTGATGTLGGLFARHLVTAYGVRRLLLTSRRGPEAEGAAELVAEL-EQLGAHVELVACD 4675 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 D + +A LL + +E PL + H AGVLDD +LS+ PER L PK A + Sbjct: 4676 AADRSALAALLGAVPSE-HPLTAVVHTAGVLDDGILSSLTPERVAAVLRPKVDAAWNLHE 4734 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWG-- 3473 GQ NYA AN+ L+ L +RRA+GL AT + +G W Sbjct: 4735 LTRELGLSAFVLFSGAAAAFGAAGQGNYAAANSFLEALAEQRRAEGLPATSLAWGLWAPQ 4794 Query: 3474 QGGMAS--SEAATANITAQGLIPL--DPSAALHALAEVIANGSGQATVLKANWQRAAKVL 3529 GGMA E I G+ L D L A + L RA V Sbjct: 4795 TGGMAQQLDEVDLRRIARDGVGGLSGDEGLGLFDTAMTVDAAVLLPMRLDLAVARAQAVS 4854 Query: 3530 GSARPPILDLVLPSAAGEAT-------GDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL 3582 P +L ++ A A G S L +L +P +R + + + V L Sbjct: 4855 TGETPALLRALIRVPARRAVEQRTAADGASPLAARLSALPDAEREDMLLDLVCGRVAEVL 4914 Query: 3583 RLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV 3640 A A F +LG DSL A+ELRN L + G ++ T VFDYPT LA +L+ Sbjct: 4915 GHTDARAVDADRAFKELGFDSLTAVELRNVLKAATG--LRLSPTLVFDYPTPVALARHLL 4972 Query: 3641 GQL 3643 +L Sbjct: 4973 AEL 4975 Score = 40.4 bits (93), Expect = 5.3 Identities = 31/77 (40%), Positives = 40/77 (51%), Gaps = 8/77 (10%) Query: 3582 LRLASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 LR A+P FLDLG DSL A++L RL + G + + T FD+PT LA +L Sbjct: 60 LRDAAPDTLDPHRPFLDLGFDSLAAVDLHARLVAGTGLRLPV--TLAFDHPTPAHLARHL 117 Query: 3640 ----VGQLPDAEAPETA 3652 +G AE P TA Sbjct: 118 HAAILGLTGPAETPVTA 134 >tr|Q8GBX6|Q8GBX6_SORCE Tax_Id=56 (spiH)SubName: Full=Polyketide synthase;[Sorangium cellulosum] Length = 5017 Score = 1636 bits (4237), Expect = 0.0 Identities = 1122/3033 (36%), Positives = 1507/3033 (49%), Gaps = 168/3033 (5%) Query: 15 AIIGYAARFPGAAS-AEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAG 73 AI+G R PG + + LL R+A++ +P RWD+ FDPDP GK R A Sbjct: 1592 AIVGVGLRLPGGVDDVDALFRLLEGERDAVAPIPASRWDVGAVFDPDPEAKGKTYVRHAA 1651 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 +D V FDA FFG+S RE R +DPQHR+L+ETAW+A+E + I P SL +S TGVFVG Sbjct: 1652 MLDRVDLFDAGFFGISPREARHVDPQHRLLLETAWQALEAATIVPASLRDSTTGVFVGAG 1711 Query: 134 THDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQ 193 DY + S + EAY A+GT+ + AAGR+++ LGLQGPA+++DTACSSSLVA+H Sbjct: 1712 ASDYAVLQSSA---EDAEAYAAMGTAASFAAGRLAFTLGLQGPALSIDTACSSSLVALHL 1768 Query: 194 ACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGV 253 ACQ+LR ECDLALA G V+ +P + S LAPDGR KTF A ADG+ RGEG V Sbjct: 1769 ACQSLRQGECDLALAAGVQVMASPEVFVILSRTRALAPDGRSKTFSANADGFGRGEGVVV 1828 Query: 254 VVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADV 313 + ++RL DA +G + AV+RG+A+N DGAS G+T PNG +QQ+V+ AL A L P DV Sbjct: 1829 LALERLRDARANGHPVLAVVRGTAVNHDGASSGITAPNGSSQQKVLRAALDDARLAPTDV 1888 Query: 314 GYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXX 373 +E HGTGTSLGDPIE QA V G GRAPE PL +G+ KTNIGHLE Sbjct: 1889 DVVECHGTGTSLGDPIEVQALAAVYGEGRAPERPLRLGAVKTNIGHLEFASGLAGVVKIV 1948 Query: 374 XXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRN--GKPRIAGVSSFGFAGTNA 431 L + TLP ++ +PHI W+ LP+ VV PW+R+ G PR AGVS+FG +GTNA Sbjct: 1949 ASLRHGTLPATIHTNPRNPHIDWDALPVRVVDAAEPWERSADGSPRRAGVSAFGLSGTNA 2008 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADV 491 HVI+EEAP P LSA++ AL A RD L P A L DV Sbjct: 2009 HVIVEEAPEPDAPKAARGALPLSGALPFVLSAKSDAALRAQAAALRDQLARTPDAALVDV 2068 Query: 492 SHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQG 551 + T R+ + RAA+ + + + L LA APG + A K A+LFTGQG Sbjct: 2069 AAALATTRSQFDHRAAIAASDHGALVAALEGLAAGVAAPGTFVAKG-AADKLAFLFTGQG 2127 Query: 552 SQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYA 611 +Q M R L+D PVF + + A + L++PL DV+F + S L T + Sbjct: 2128 AQRAAMGRGLYDAFPVFRDALDAVASHLDRELDRPLRDVLFAPK--GSELASLLDRTEFT 2185 Query: 612 QPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGS 671 QPALFA+E+ L RL ++WG PDV++GHSVG+ +AA VAGV + D L+A R RL + Sbjct: 2186 QPALFALEVALFRLVEAWGVTPDVLLGHSVGELAAAHVAGVLSLADACTLVAARARLMQA 2245 Query: 672 LPA--GGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLVADG 728 LPA G + T E L +AA N ++TV++G + A A G Sbjct: 2246 LPARDGAMVTVHATEAEVLAALEGRDGRAEIAAINAPSSTVIAGDVDAVLRVAAHFEARG 2305 Query: 729 VRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYW 788 + L SHAFHS +DP+LD F A+ L + P+ ++ N TG R YW Sbjct: 2306 RKATRLRVSHAFHSHHMDPMLDAFRRVAEGLTFHPPRIPIVSNVTGRLAADEIRSPD-YW 2364 Query: 789 RRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTA 848 RH R V FA + TL E+GP VL+A +A + + +LR A Sbjct: 2365 VRHVRSAVRFADGINTLEADGVSSFFELGPHGVLSALGESALANAQREVAFVPALRDGRA 2424 Query: 849 DHRQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLPTYPFEHRQFWFSDNRAIDRDTQTA 907 D +T A+++ + GH D+ AF P D + + LPTY F+ +FW RD Sbjct: 2425 DVDALTAALSSLHVRGHRVDWAAFFGPFDPQTVALPTYAFQRDRFWLDAPAGATRD---- 2480 Query: 908 SAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTL--RVLNKLAARHNQQRSTHVDP 965 A P R ++ G + L A ++ D + +L L+A + + Sbjct: 2481 EAAPAAPEDAAFWRAVDAGDVGALGATLNASGEDHLSALATLLPALSAWRRARDERSLVD 2540 Query: 966 DARYEIRWDXXXXXXXXXXXXXDWILV---GDDTAAVLEFADALTAGGHRHQIVALPGSD 1022 RY + W W+LV G + A E ALTA G + + ++ Sbjct: 2541 ALRYRVVWKPLTPTAARDVAGT-WLLVTLAGAEDALARELERALTARGAEVITMPIAPAE 2599 Query: 1023 ADEAQLVDTLRAA--SAGELY-VVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDA 1079 AD +L ++ A AGEL +V AA D L L RL +A D Sbjct: 2600 ADRVRLAVRVQGALADAGELRGIVSFAALDETTLATHTALPAG---LALTLRLVQALGDM 2656 Query: 1080 ELRSPIWLVTRDGQRVTDTDTVVPE-QSCLWGFGRAAALELPHIWGGLADLSGADTEWPR 1138 + +P+WLVTR +D + QS WG GR LE P WGGL D++ DT R Sbjct: 2657 GIEAPLWLVTRGAVSTGRSDRLASAAQSMTWGLGRVVGLEHPERWGGLVDVADGDTIDAR 2716 Query: 1139 LIARITS---PRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIG 1195 + R+ + RDGEDQ+ALR ++A RLVR + T LVTGG GA+G Sbjct: 2717 ALDRLVTLLASRDGEDQLALRPTGIFARRLVRAPLGDAPPARTYTARGTSLVTGGTGALG 2776 Query: 1196 LEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMT 1255 VA +LA GA H+VL SRR E V + DVAD VA L+ Sbjct: 2777 AHVARFLAGRGAEHLVLVSRRGEDAPGAGALRAELEALGARVTLAACDVADRASVAALLA 2836 Query: 1256 TVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFF 1315 + A+ P+ +VHA G + L+ D V V A KV GA HL E L D +LD F Sbjct: 2837 RLDAQGDPVRAVVHAGGVVAQAALASTDLDGVQAVVAAKVRGALHLHELLGD--RELDAF 2894 Query: 1316 VSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG-----MADAE 1370 V +S A VWG Q AY A NAFLD LA R G+TA S+ +G WA G ADA+ Sbjct: 2895 VLFASGAGVWGSGQQGAYAAGNAFLDALAEVRRAAGLTATSIAWGAWAGGGMLADHADAD 2954 Query: 1371 SRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRAFLSELE 1429 + L +RG+ ++PA A+A +A + G VA +DW+RF P + A R L +L Sbjct: 2955 AEVELRKRGLVPMAPALAIAALAGALDHGETAVTVASVDWARFAPAFASARPRPLLLDLP 3014 Query: 1430 S--ELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQR-KSLITNYLRNAVAEVTRVDADEI 1486 LVE L R + L+ + A + DA I Sbjct: 3015 EAQRAIEAPSAPAGADGASADRALVEALRPLSEADRARHLVELVVAETAAVLGHADASAI 3074 Query: 1487 RDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYL-----LVEVLG 1541 GFFDLG+DSL+AVEL R++ G ++P T+ DHP A Y+ L L Sbjct: 3075 DPHKGFFDLGLDSLVAVELLRKLRARTGVELPATVTFDHPSPHRLATYVREALPLDAPLA 3134 Query: 1542 LGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDRWD 1600 + T R +S+ A D+PIA+V + R PG D E W L G D + +P+DRWD Sbjct: 3135 PADATTAR-SSSAHAAIDEPIAIVGLGLRLPGGVEDREGLWSFLEQGRDGVGPIPKDRWD 3193 Query: 1601 IDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLE 1660 D YDPDP+ GK+Y R FFGISPREA ++PQ RL+LET W+ LE Sbjct: 3194 ADAIYDPDPEAKGKSYVREAALLDRVDLFDAAFFGISPREAKQVDPQHRLLLETAWQALE 3253 Query: 1661 RAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGF 1720 A P+ L+ + TGVF G+ ++YA L S ++ + + G + +GR+AF LG Sbjct: 3254 EATIVPASLKDTSTGVFVGIGLSDYA--LMQGSAEETDAYAAMGTLSSFAAGRLAFTLGL 3311 Query: 1721 EGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVG 1780 +GPA+++DTACSS+LVA+H ACQ+L+ G+CDLALAGGV V+ V SR R L+ G Sbjct: 3312 QGPALSIDTACSSSLVALHLACQSLRKGECDLALAGGVQVMTLAEPFVLLSRTRALAADG 3371 Query: 1781 RCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGG 1840 R KTF A ADGY R EG VL L+RL DA G RV AV+ ++VN DGASSG+T PNG Sbjct: 3372 RSKTFSAHADGYGRGEGVVVLALERLRDAEARGRRVLAVVRGTAVNHDGASSGITAPNGT 3431 Query: 1841 AQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSV 1900 +QQ+++ A L AGL+ ADVD +E HGTGT LGDPIEVQ PLL+G+V Sbjct: 3432 SQQKVLRAALGDAGLAPADVDVVECHGTGTALGDPIEVQALAAVYGEGRAAERPLLLGAV 3491 Query: 1901 KTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPW--Q 1958 K+NIGH E+ASG AG+ K+V +L+HG LP ++H +PH+ WDAL VRV+D W + Sbjct: 3492 KSNIGHLEAASGLAGVAKIVTALEHGALPATIHSRPRNPHVDWDALHVRVVDAAELWARR 3551 Query: 1959 TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV--LAL 2016 RRAGVS+FG +GTNAH ++EEAP TD+ P + L Sbjct: 3552 DEETPRRAGVSAFGLSGTNAHAIIEEAP------------RARRGAAATDEPPPAVPVVL 3599 Query: 2017 SARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXX 2076 SA+S AL A R ++ PG + DV + RSHFE+RAA+V + Sbjct: 3600 SAKSERALRAQAERLRAHVTGRPGDALVDVAASLATTRSHFEHRAAIVARDLGALEDALA 3659 Query: 2077 XXXXXXTPAGVVRGEHVHRPT---TAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEA 2133 +PAG V V R T A LFTGQG Q M R L+ VF Sbjct: 3660 GLAEGRSPAGTV----VSRTTGGKLALLFTGQGGQRAAMGRGLYGAFSVFRDAFDAACSY 3715 Query: 2134 VADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHS 2192 + L PL DV+FA E A LL T + Q +LFA+E+ L RL ++W + P V+LGHS Sbjct: 3716 LDRELEHPLRDVVFAPRGSELAALLDETLYTQTSLFALEVALFRLVEAWGVTPHVLLGHS 3775 Query: 2193 VGQYAAACVAGVFSLDDGARLMAERGRMFGSLP-EGGRMVAVFADAEHV----EQVAGEF 2247 +G+ AA VAGV SL+D L+A R R+ +LP MVAV A V + +AG Sbjct: 3776 IGELVAAHVAGVLSLEDACTLVAARARLMHALPRRDAAMVAVHACESEVLDALDAMAGLD 3835 Query: 2248 PRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXX 2306 R S+ A N P +TV++G E + + RFE G + + L SHAFHS LDP+L+ Sbjct: 3836 GRASIAAVNAPSSTVVAGDREAVLAVAARFEALGRKTSRLRVSHAFHSHHLDPMLEAFRR 3895 Query: 2307 XXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM 2366 P +P+V N TGA + A YW RH+R V+FA+ + + A G S + Sbjct: 3896 VAEGVRFEPPRIPIVSNVTGARASNDDLCSADYWVRHARGTVRFADGLEALRADGVSTFL 3955 Query: 2367 EIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR 2426 E+GP VL + A + +LR G D + AL + + GH D+ A Sbjct: 3956 ELGPHAVLCALGHETLESEAVA--FLPALRDGRDDVDTLTAALGALHARGHHVDWDAFFA 4013 Query: 2427 Q-PRRPVELPTYPFQRRRFW---PKASSIAVDGGTAAS--GILGSGKDLASGDTIYTSRL 2480 V LPTY FQR RFW PKA S +A + G+ DL G ++T + Sbjct: 4014 PFNAGRVALPTYAFQRERFWLDMPKAKSSRAAAADSAGRYPLAGTRLDLPDGSAVHTLDI 4073 Query: 2481 SVKSQPWLADHVIYGTVVVPGATYAAMALAAV-----GTPARLKDVFFYEPIILPEKASR 2535 +QP+LADH +YG +VVPGA + A+ LA +P L+DV F + E + Sbjct: 4074 GPGAQPYLADHSVYGRIVVPGAFHLAVLLAVAESHWPDSPLELRDVEFVRALTFEEPSET 4133 Query: 2536 -EVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDE 2594 V++ L PA GG F H+ + W+ +A T+ G+ P +A E Sbjct: 4134 VAVRVHLTPA-GGDGKGF--HATVATQTEGAWTTHATATL---GAAPPSALARHPRAAHE 4187 Query: 2595 VIERLERMRP-QDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSE 2653 + E R L +F + WGP W ++ GD VG + A Sbjct: 4188 PLAGDEPSRAVARLMASFEAFNVEWGPKWRWLRQTTHAGDRTGVG--YLAAPDGVPTDDA 4245 Query: 2654 PMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLR--------YGQ---------VTLA 2696 P+ L+D V + PL YG+ V Sbjct: 4246 PLPGGLVDNAFAVVGSAVTGLPAHDNRSTSNVPPLPFSIERLVWYGRAETPCWADFVMRG 4305 Query: 2697 EKMP---RRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGL 2753 E P R W R SE E G + I +RAP + L L Sbjct: 4306 EITPDADRYIGDITLWSREGASSEGASRE-------GTPIATIEGLAFRRAPADKFLPEL 4358 Query: 2754 GGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVL 2813 R LY L W E P ++ G W + G D L + + D D+ L + L Sbjct: 4359 ---PARNLYALTWPE--QPAASRPPRGRWALLGEDSLG--IATGIAADAYPDVDALRDAL 4411 Query: 2814 SQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKL---- 2869 RGA V C T L+S+VH A ++ L Sbjct: 4412 ----GRGAPCPDTVAVCLATAHGPSDTDE----------TELVSSVHTAAARALALLNAW 4457 Query: 2870 -------PGGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSS 2921 L ++T+ VA +GE V D AALWG R+ E LVD DGS Sbjct: 4458 LSDERLASSTLVLLTQRAVATCAGEDVLDLASAALWGLVRSAQAENRDRAILLVDLDGSD 4517 Query: 2922 EAVDXXXXXXXXP-GIQEPEIAVRQGKLLASRL 2953 + EP++A+R G+ LA RL Sbjct: 4518 ASRRALPYAVGGALDDAEPQLALRDGRRLAPRL 4550 Score = 1518 bits (3930), Expect = 0.0 Identities = 985/2490 (39%), Positives = 1300/2490 (52%), Gaps = 117/2490 (4%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAG 73 AI+G R PG + W L +GR+AI+ +P RW+ + +DPDP GK R A Sbjct: 39 AIVGLGLRLPGGIHDRDTLWTFLEEGRDAIAPIPASRWNADATYDPDPDAVGKSYVRDAA 98 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 +D V FDA FFG+S RE + +DPQHR+L+ET+W+A+E +GI P SL +S TGVFVG Sbjct: 99 MLDRVDLFDADFFGISPREAKYVDPQHRLLLETSWQALEDAGIVPASLRDSKTGVFVGTG 158 Query: 134 THDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQ 193 DY + SD EAY +G ++ AAGR+++ LGLQGPA+++DTACSSSLVA+H Sbjct: 159 ASDYAFLQSDR---DASEAYAFMGMISSFAAGRLAFTLGLQGPALSIDTACSSSLVALHL 215 Query: 194 ACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGV 253 ACQ+LR ECDLAL G V+ +P + S LA DGR KTF A ADGY RGEG V Sbjct: 216 ACQSLRQGECDLALVAGVQVMSSPEVFVLLSRTRALASDGRSKTFSANADGYGRGEGVVV 275 Query: 254 VVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADV 313 + V+RL DA G I AVIRGSA+N DG S G+TVPNG AQQ+V+ AL A L PADV Sbjct: 276 LAVERLRDARAKGRPILAVIRGSAVNHDGTSSGITVPNGPAQQKVLRAALDDARLVPADV 335 Query: 314 GYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXX 373 +E HGTGTS+GDPIE A V G GR + PL +G+ KTNIGHLE Sbjct: 336 DVVECHGTGTSIGDPIEVNALAAVYGEGRPKDRPLFLGALKTNIGHLEFASGLAGVAKMV 395 Query: 374 XXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR--NGKPRIAGVSSFGFAGTNA 431 + + TLP L+ +P + W+ LP+ VV PW R +G PR AGV++ G +GTNA Sbjct: 396 ASMRHATLPATLHTSPLNPLVDWDALPVRVVDAARPWTRRDDGAPRRAGVTAIGLSGTNA 455 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADV 491 HVI+EEAPA P T + VL LS +T EAL A L P ARL D+ Sbjct: 456 HVIVEEAPAEPEPTTPDAAPALPAVPVL-LSGKTDEALRAQAARLHAHLAGRPDARLVDI 514 Query: 492 SHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQG 551 + + T R H ++RAA+V R+ + L ALA PG V + A + ++F GQG Sbjct: 515 AASLATTRTHFDRRAAVVAADRDELLGALDALARGEAGPGSVVASAIPAGRVVFVFPGQG 574 Query: 552 SQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYA 611 SQ+ GMAR L + VF + + C A+A + L V+ DGD + L Sbjct: 575 SQWVGMARALLASSVVFRDEIAACERALAPHVAWSLGAVLRG----DGDEATLLGRVDVV 630 Query: 612 QPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGS 671 QP LFAV + LA LW+S G PD VVGHS G+ +AA VAG +ED A+++A R R Sbjct: 631 QPVLFAVMVALAALWRSIGVTPDAVVGHSQGEIAAAYVAGALSLEDAAKVVALRARALTK 690 Query: 672 LPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGAN-TVLSGPAKDLESAVATLVADGV 729 + G MAAV A + RL ++++AA N T+++G +++ V L A + Sbjct: 691 IAGRGAMAAVELGARDTEARLAPFGDAIAIAAINSPRATLVAGDTDAIDALVRDLEAAQI 750 Query: 730 RCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWR 789 + +A HSA ++ I + + +E R L TG+ L S RLD A+W Sbjct: 751 FARKVRVDYASHSAHVEAIERELLADLAGIEPRAGAVPLYSAVTGAKLDGS-RLDAAHWF 809 Query: 790 RHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTAD 849 R+ R V F + R L D R +E+ P PVL V++SLR D Sbjct: 810 RNLRSTVRFEDATRALHDDGHRFFVEVSPHPVLALALDETLSSIGGDAAVVSSLRRDEGD 869 Query: 850 HRQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLPTYPFEHRQFWFSDNRAIDRDTQTAS 908 + + +A GH D+ AF P AR++ LPTY F+ +FW A D + Sbjct: 870 LERFLLSAGELHARGHAIDWGAFFAPLGARRVTLPTYAFQRERFWLDAGDASDDEDAAPG 929 Query: 909 AGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLR-----VLNKLAARHNQQRSTHV 963 A + T R +E G + AAL D V + R ++ L+A +R Sbjct: 930 ASA---EETAFWRAIERGDV---AALSDALHVADSGRRSALESLMPALSAWRRSRREQST 983 Query: 964 DPDARYEIRWDXXXXXXXXXXXXXDWILVG-----DDTAAVLEFADALTAGGHRHQIVAL 1018 RY + W W++V D A+ L A ALT G +AL Sbjct: 984 VGAWRYRVEW-RPVSAASRGDVAGTWLVVAPAGVASDLASAL--AAALTERGADVVPLAL 1040 Query: 1019 PGSDADEAQLVDTLRAASAGE--------LYVVHIAAGDGAAAPMRDLLRVQHRTLGGLR 1070 SD LR A AG L + A DG A L R Sbjct: 1041 EASDITAHDAASRLRDAIAGRPAIRGVLTLTPLDTAPLDGRPAVPAGLARSL-------- 1092 Query: 1071 RLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADL 1129 L +A + + +PIW+VTR + +D + P Q+ WG GR +LE P WGGL DL Sbjct: 1093 ALVQALAELAIEAPIWIVTRGAVAIGRSDRIESPVQAMAWGLGRVVSLEQPERWGGLVDL 1152 Query: 1130 SGAD-------TEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVRED 1182 A T RL+A + S R+GED++ALR ++A RL R D P E Sbjct: 1153 PRAHADGALDATAIERLVAALGS-REGEDELALRPTGLFARRLAR--APLGDAPAQRFEP 1209 Query: 1183 R-TYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVIT 1241 R T LVTGG GA+G VA +LA HGA H+VL SRR + V + Sbjct: 1210 RGTVLVTGGTGALGAHVARWLARHGAAHLVLASRRGAAAPGAEALRAELTELGARVTIAA 1269 Query: 1242 ADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHL 1301 DVAD + L + AE PL I H AG I L L ++ V GK A L Sbjct: 1270 CDVADRAAIEELFAALPAE-EPLTAIFHTAGVIDDGVLGSLTPERLETVLHGKADAARTL 1328 Query: 1302 SEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGP 1361 E LT R DL FV SS A V+G GQ +Y AANAFLD LA R G+ A SV +G Sbjct: 1329 HE-LTKTR-DLAAFVLFSSAAGVFGNAGQASYAAANAFLDALAEERRALGLRATSVAWGA 1386 Query: 1362 WA-AGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQA 1419 WA AGM + L + G + P A+A +A + V +A IDW+RF P Y A Sbjct: 1387 WAGAGMLTFDVAQGLRRGGFAAMEPEIAVAALASALDRDETHVTIASIDWARFAPSYASA 1446 Query: 1420 GRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT 1479 +R +++L + + + + L++ L A + Sbjct: 1447 RQRPLVADLPDARRALDAQPSASTEHDETALVATLRALSGEARLRHLVSLVLAQTAAVLG 1506 Query: 1480 RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLL--V 1537 D + + GFFDLG+DSLMAVELRRR+++ G +P T+ D P A +LL + Sbjct: 1507 HADRSRLDPQRGFFDLGLDSLMAVELRRRLQKATGVKLPATITFDRPSPHRLAGFLLDAL 1566 Query: 1538 EVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAPDP-ESFWELLAGGVDAIREVPE 1596 + G T+ R + +D+PIA+V V R PG D ++ + LL G DA+ +P Sbjct: 1567 PLGGAAPSTDARPRAARADASDEPIAIVGVGLRLPGGVDDVDALFRLLEGERDAVAPIPA 1626 Query: 1597 DRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVW 1656 RWD+ +DPDP+ GKTY R FFGISPREA ++PQ RL+LET W Sbjct: 1627 SRWDVGAVFDPDPEAKGKTYVRHAAMLDRVDLFDAGFFGISPREARHVDPQHRLLLETAW 1686 Query: 1657 EGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAF 1716 + LE A P+ LR S TGVF G A++YA L S S + E + G A + +GR+AF Sbjct: 1687 QALEAATIVPASLRDSTTGVFVGAGASDYAVLQS--SAEDAEAYAAMGTAASFAAGRLAF 1744 Query: 1717 ALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARML 1776 LG +GPA+++DTACSS+LVA+H ACQ+L+ G+CDLALA GV V+ SP V SR R L Sbjct: 1745 TLGLQGPALSIDTACSSSLVALHLACQSLRQGECDLALAAGVQVMASPEVFVILSRTRAL 1804 Query: 1777 SPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTV 1836 +P GR KTF A+ADG+ R EG VL L+RL DA +G V AV+ ++VN DGASSG+T Sbjct: 1805 APDGRSKTFSANADGFGRGEGVVVLALERLRDARANGHPVLAVVRGTAVNHDGASSGITA 1864 Query: 1837 PNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLL 1896 PNG +QQ+++ A L A L+ DVD +E HGTGT LGDPIEVQ PL Sbjct: 1865 PNGSSQQKVLRAALDDARLAPTDVDVVECHGTGTSLGDPIEVQALAAVYGEGRAPERPLR 1924 Query: 1897 MGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVP 1956 +G+VKTNIGH E ASG AG++K+V SL+HG LP ++H +PHI WDALPVRV+D P Sbjct: 1925 LGAVKTNIGHLEFASGLAGVVKIVASLRHGTLPATIHTNPRNPHIDWDALPVRVVDAAEP 1984 Query: 1957 WQ--TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV- 2013 W+ +G RRAGVS+FG +GTNAHV+VEEAP D+P+ Sbjct: 1985 WERSADGSPRRAGVSAFGLSGTNAHVIVEEAP--------------------EPDAPKAA 2024 Query: 2014 -----------LALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAA 2062 LSA+S AL A D L+ TP + DV RS F++RAA Sbjct: 2025 RGALPLSGALPFVLSAKSDAALRAQAAALRDQLARTPDAALVDVAAALATTRSQFDHRAA 2084 Query: 2063 LVVDSVXXXXXXXXXXXXXXTPAG--VVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQ 2120 + G V +G A+LFTGQG+Q M R L+D Sbjct: 2085 IAASDHGALVAALEGLAAGVAAPGTFVAKGA---ADKLAFLFTGQGAQRAAMGRGLYDAF 2141 Query: 2121 PVFAQTVRQCAEAVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQ 2179 PVF + A + L RPL DVLFA E A LL T F QPALFA+E+ L RL + Sbjct: 2142 PVFRDALDAVASHLDRELDRPLRDVLFAPKGSELASLLDRTEFTQPALFALEVALFRLVE 2201 Query: 2180 SWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLP-EGGRMVAVFA-DA 2237 +W + PDV+LGHSVG+ AAA VAGV SL D L+A R R+ +LP G MV V A +A Sbjct: 2202 AWGVTPDVLLGHSVGELAAAHVAGVLSLADACTLVAARARLMQALPARDGAMVTVHATEA 2261 Query: 2238 EHVEQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSEL 2296 E + + G R + A N P +TV++G + + + FE G + T L SHAFHS Sbjct: 2262 EVLAALEGRDGRAEIAAINAPSSTVIAGDVDAVLRVAAHFEARGRKATRLRVSHAFHSHH 2321 Query: 2297 LDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRT 2356 +DP+LD P +P+V N TG L YW RH R V+FA+ + T Sbjct: 2322 MDPMLDAFRRVAEGLTFHPPRIPIVSNVTGR-LAADEIRSPDYWVRHVRSAVRFADGINT 2380 Query: 2357 VAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGG 2416 + A G S E+GP VL+ V +LR G AD + AL+S +V G Sbjct: 2381 LEADGVSSFFELGPHGVLSALGESALANAQREVAFVPALRDGRADVDALTAALSSLHVRG 2440 Query: 2417 HRPDFAAVHRQ-PRRPVELPTYPFQRRRFW 2445 HR D+AA + V LPTY FQR RFW Sbjct: 2441 HRVDWAAFFGPFDPQTVALPTYAFQRDRFW 2470 Score = 584 bits (1506), Expect = e-164 Identities = 362/915 (39%), Positives = 485/915 (53%), Gaps = 28/915 (3%) Query: 1557 RTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKT 1615 R +PIA+V + R PG D ++ W L G DAI +P RW+ D YDPDPD GK+ Sbjct: 33 RRHEPIAIVGLGLRLPGGIHDRDTLWTFLEEGRDAIAPIPASRWNADATYDPDPDAVGKS 92 Query: 1616 YTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTG 1675 Y R +FFGISPREA +++PQ RL+LET W+ LE AG P+ LR S+TG Sbjct: 93 YVRDAAMLDRVDLFDADFFGISPREAKYVDPQHRLLLETSWQALEDAGIVPASLRDSKTG 152 Query: 1676 VFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSAL 1735 VF G A++YA L S D E + G + +GR+AF LG +GPA+++DTACSS+L Sbjct: 153 VFVGTGASDYAFLQSDR--DASEAYAFMGMISSFAAGRLAFTLGLQGPALSIDTACSSSL 210 Query: 1736 VAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRS 1795 VA+H ACQ+L+ G+CDLAL GV V+ SP V SR R L+ GR KTF A+ADGY R Sbjct: 211 VALHLACQSLRQGECDLALVAGVQVMSSPEVFVLLSRTRALASDGRSKTFSANADGYGRG 270 Query: 1796 EGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGL 1855 EG VL ++RL DA G + AVI S+VN DG SSG+TVPNG AQQ+++ A L A L Sbjct: 271 EGVVVLAVERLRDARAKGRPILAVIRGSAVNHDGTSSGITVPNGPAQQKVLRAALDDARL 330 Query: 1856 SGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAG 1915 ADVD +E HGTGT +GDPIEV PL +G++KTNIGH E ASG AG Sbjct: 331 VPADVDVVECHGTGTSIGDPIEVNALAAVYGEGRPKDRPLFLGALKTNIGHLEFASGLAG 390 Query: 1916 LIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPW--QTNGRVRRAGVSSFGF 1973 + K+V S++H LP +LH +P + WDALPVRV+D PW + +G RRAGV++ G Sbjct: 391 VAKMVASMRHATLPATLHTSPLNPLVDWDALPVRVVDAARPWTRRDDGAPRRAGVTAIGL 450 Query: 1974 TGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLA----LSARSPEALVELAR 2029 +GTNAHV+VEEAP + D +P + A LS ++ EAL A Sbjct: 451 SGTNAHVIVEEAPAEPEPTTP-------------DAAPALPAVPVLLSGKTDEALRAQAA 497 Query: 2030 RYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVR 2089 R L+ P + D+ + R+HF+ RAA+V G V Sbjct: 498 RLHAHLAGRPDARLVDIAASLATTRTHFDRRAAVVAADRDELLGALDALARGEAGPGSVV 557 Query: 2090 GEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFAT 2149 + ++F GQGSQ+ GMAR L + VF + C A+A + L VL Sbjct: 558 ASAIPAGRVVFVFPGQGSQWVGMARALLASSVVFRDEIAACERALAPHVAWSLGAVLRG- 616 Query: 2150 DRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDD 2209 D + A LL QP LFAV + LA LW+S + PD V+GHS G+ AAA VAG SL+D Sbjct: 617 DGDEATLLGRVDVVQPVLFAVMVALAALWRSIGVTPDAVVGHSQGEIAAAYVAGALSLED 676 Query: 2210 GARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF-PRVSVGAYNGPN-TVLSGPGE 2267 A+++A R R + G M AV A E F +++ A N P T+++G + Sbjct: 677 AAKVVALRARALTKIAGRGAMAAVELGARDTEARLAPFGDAIAIAAINSPRATLVAGDTD 736 Query: 2268 DLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGA 2327 ++ +V E I + +A HS ++ + +PL TGA Sbjct: 737 AIDALVRDLEAAQIFARKVRVDYASHSAHVEAIERELLADLAGIEPRAGAVPLYSAVTGA 796 Query: 2328 VLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMA 2387 L G LDA +W R+ R V+F ++ R + G +E+ P PVL A + Sbjct: 797 KLDGSR-LDAAHWFRNLRSTVRFEDATRALHDDGHRFFVEVSPHPVLALALDETLSSIGG 855 Query: 2388 APRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWP 2446 V+SLR+ D + + + GH D+ A R V LPTY FQR RFW Sbjct: 856 DAAVVSSLRRDEGDLERFLLSAGELHARGHAIDWGAFFAPLGARRVTLPTYAFQRERFWL 915 Query: 2447 KASSIAVDGGTAASG 2461 A A D AA G Sbjct: 916 DAGD-ASDDEDAAPG 929 Score = 174 bits (442), Expect = 2e-40 Identities = 125/364 (34%), Positives = 168/364 (46%), Gaps = 19/364 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA GA +VL SRR D A+ E R+ A DV Sbjct: 2767 LVTGGTGALGAHVARFLAGRGAEHLVLVSRRGEDAPGAGALRAELEALGARVTLAACDVA 2826 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D A VA LLAR+ A+ P+ + H GV+ A L++ + + + +A K GA H Sbjct: 2827 DRASVAALLARLDAQGDPVRAVVHAGGVVAQAALASTDLDGVQAVVAAKVRGALHLHELL 2886 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 Q YA NA LD L RRA GL AT I +G W GGM Sbjct: 2887 GDRELDAFVLFASGAGVWGSGQQGAYAAGNAFLDALAEVRRAAGLTATSIAWGAWAGGGM 2946 Query: 3478 ASSEA---ATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 + A A + +GL+P+ P+ A+ ALA + +G TV +W R A SARP Sbjct: 2947 LADHADADAEVELRKRGLVPMAPALAIAALAGALDHGETAVTVASVDWARFAPAFASARP 3006 Query: 3535 PILDLVLPSA------------AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL 3582 L L LP A A A+ D L++ L + RA + E + E L Sbjct: 3007 RPLLLDLPEAQRAIEAPSAPAGADGASADRALVEALRPLSEADRARHLVELVVAETAAVL 3066 Query: 3583 RLASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV 3640 A A F DLG DSL+A+EL +L ++ G + AT FD+P+ LA Y+ Sbjct: 3067 GHADASAIDPHKGFFDLGLDSLVAVELLRKLRARTG--VELPATVTFDHPSPHRLATYVR 3124 Query: 3641 GQLP 3644 LP Sbjct: 3125 EALP 3128 Score = 160 bits (404), Expect = 5e-36 Identities = 130/370 (35%), Positives = 171/370 (46%), Gaps = 24/370 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRD---PDESAQRAIDEITERHKCRIHTYAA 3354 L+TGG GA+G H A +LA+ GA +VL SRR P A RA E+TE R+ A Sbjct: 1214 LVTGGTGALGAHVARWLARHGAAHLVLASRRGAAAPGAEALRA--ELTEL-GARVTIAAC 1270 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXX 3414 DV D A + +L A + AE PL I H AGV+DD +L + PER T L KA A Sbjct: 1271 DVADRAAIEELFAALPAE-EPLTAIFHTAGVIDDGVLGSLTPERLETVLHGKADAARTLH 1329 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQA+YA ANA LD L +RRA GL AT + +G W Sbjct: 1330 ELTKTRDLAAFVLFSSAAGVFGNAGQASYAAANAFLDALAEERRALGLRATSVAWGAWAG 1389 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA-- 3532 GM + + A + G ++P A+ ALA + T+ +W R A SA Sbjct: 1390 AGMLTFDVA-QGLRRGGFAAMEPEIAVAALASALDRDETHVTIASIDWARFAPSYASARQ 1448 Query: 3533 RPPILDL--------VLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 RP + DL PSA+ E ++ L+ L + R + + + L Sbjct: 1449 RPLVADLPDARRALDAQPSASTE-HDETALVATLRALSGEARLRHLVSLVLAQTAAVLGH 1507 Query: 3585 ASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 A + F DLG DSLMA+ELR RL G K + AT FD P+ LA +L+ Sbjct: 1508 ADRSRLDPQRGFFDLGLDSLMAVELRRRLQKATGVK--LPATITFDRPSPHRLAGFLLDA 1565 Query: 3643 LP-DAEAPET 3651 LP AP T Sbjct: 1566 LPLGGAAPST 1575 Score = 146 bits (368), Expect = 7e-32 Identities = 162/574 (28%), Positives = 236/574 (41%), Gaps = 70/574 (12%) Query: 989 WILVGDDTAAVLE------------FADALTAGGHRHQIVAL------PGSDADEAQLVD 1030 W L+G+D+ + DAL G VA+ SD DE +LV Sbjct: 4382 WALLGEDSLGIATGIAADAYPDVDALRDALGRGAPCPDTVAVCLATAHGPSDTDETELVS 4441 Query: 1031 TLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTR 1090 ++ A+A L +++ D A +L Q + T Sbjct: 4442 SVHTAAARALALLNAWLSDERLASSTLVLLTQRA----------------------VATC 4479 Query: 1091 DGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRD-G 1149 G+ V D + + LWG R+A E L DL G+D L + D Sbjct: 4480 AGEDVLDLAS-----AALWGLVRSAQAENRDRAILLVDLDGSDASRRALPYAVGGALDDA 4534 Query: 1150 EDQIALRGDAVYAPRLVRRTG----------EPSDTPLPVREDRTYLVTGGLGAIGLEVA 1199 E Q+ALR APRL R S TP + + T LVTGG G +G VA Sbjct: 4535 EPQLALRDGRRLAPRLARVAAPTAATANAATSTSATPRALDPEGTVLVTGGTGTLGALVA 4594 Query: 1200 GYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVA 1258 L HG H+VL SRR P + V + AD A+ +AR++ + Sbjct: 4595 RRLVERHGVKHLVLLSRRGPDAPGATDLAAELQARGASVVLAAADAAEPAALARVLLAIP 4654 Query: 1259 AELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVST 1318 + P L +VHAAG + LS + A + V KV A +L E + L FV Sbjct: 4655 HDRP-LTAVVHAAGTLDDGVLSSMTPARLSAVLRAKVDAAVNLDEQTR--HSPLRAFVLF 4711 Query: 1319 SSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA--AGMADAESRA--- 1373 SS++ V G Q+ Y AANAFLD LA R RG+ AV++++G WA +G+ +A Sbjct: 4712 SSLSGVLGSPAQSNYAAANAFLDALAHRRAARGLPAVALDWGYWAQTSGLTKHLEQADLR 4771 Query: 1374 RLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELX 1433 R+ + G+R L+ EALA +A +V + F + A + L + Sbjct: 4772 RIARGGLRPLASDEALALFDLALAQDAPCLVP----AAFDADALRKSGDALSALLRGLVA 4827 Query: 1434 XXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDAD-EIRDEAGF 1492 L +L +R ++ + +R VA V V + +I Sbjct: 4828 GPRARAQRASGAGAASALKLRLASLAPLERHRMLLDVVRADVATVLGVASPLDIEPGRPL 4887 Query: 1493 FDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHP 1526 +LG+DSLMA+ELR R+ G + TL+ DHP Sbjct: 4888 QELGLDSLMAIELRNRLAAATGLRLSATLLFDHP 4921 Score = 125 bits (313), Expect = 2e-25 Identities = 114/365 (31%), Positives = 162/365 (44%), Gaps = 20/365 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TGG G +G A L + G +VL SRR PD + + + AAD Sbjct: 4581 LVTGGTGTLGALVARRLVERHGVKHLVLLSRRGPDAPGATDLAAELQARGASVVLAAADA 4640 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 + A +A +L I + P L + H AG LDD +LS+ P R L K A + Sbjct: 4641 AEPAALARVLLAIPHDRP-LTAVVHAAGTLDDGVLSSMTPARLSAVLRAKVDAAVNLDEQ 4699 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ-G 3475 P Q+NYA ANA LD L +R A+GL A +++G W Q Sbjct: 4700 TRHSPLRAFVLFSSLSGVLGSPAQSNYAAANAFLDALAHRRAARGLPAVALDWGYWAQTS 4759 Query: 3476 GMAS--SEAATANITAQGLIPL--DPSAALHAL-----AEVIANGSGQATVLKANWQRAA 3526 G+ +A I GL PL D + AL L A + + A L+ + + Sbjct: 4760 GLTKHLEQADLRRIARGGLRPLASDEALALFDLALAQDAPCLVPAAFDADALRKSGDALS 4819 Query: 3527 KVL-GSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA 3585 +L G P S AG A S L +L + +R + + ++ +V L +A Sbjct: 4820 ALLRGLVAGPRARAQRASGAGAA---SALKLRLASLAPLERHRMLLDVVRADVATVLGVA 4876 Query: 3586 SP--PAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 SP +LG DSLMAIELRNRL + G ++AT +FD+PT LA+ + G+L Sbjct: 4877 SPLDIEPGRPLQELGLDSLMAIELRNRLAAATG--LRLSATLLFDHPTPEALAKLISGKL 4934 Query: 3644 PDAEA 3648 EA Sbjct: 4935 LHDEA 4939 Score = 41.2 bits (95), Expect = 3.1 Identities = 55/209 (26%), Positives = 75/209 (35%), Gaps = 20/209 (9%) Query: 2762 YTLGWHEVPPPPSADDAVGTWLI---AGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHA 2818 Y + W V S D GTWL+ AG A +R D+ L S A Sbjct: 989 YRVEWRPVSAA-SRGDVAGTWLVVAPAGVASDLASALAAALTERGADVVPLALEASDITA 1047 Query: 2819 RGAGF---SGVVWRCATPG----RKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPG 2871 A + R A G + L+ V A +++ P Sbjct: 1048 HDAASRLRDAIAGRPAIRGVLTLTPLDTAPLDGRPAVPAGLARSLALVQALAELAIEAP- 1106 Query: 2872 GLWIVTEHGVACESGEPVD-PVQAALWGFGRTTINEEPALHCRLVD-----CDGSSEAVD 2925 +WIVT VA + ++ PVQA WG GR E+P LVD DG+ +A Sbjct: 1107 -IWIVTRGAVAIGRSDRIESPVQAMAWGLGRVVSLEQPERWGGLVDLPRAHADGALDATA 1165 Query: 2926 XXXXXXXXPGIQ-EPEIAVRQGKLLASRL 2953 + E E+A+R L A RL Sbjct: 1166 IERLVAALGSREGEDELALRPTGLFARRL 1194 >tr|A4F5C7|A4F5C7_SORCE Tax_Id=56 (spiH)SubName: Full=Polyketide synthase;[Sorangium cellulosum] Length = 5005 Score = 1636 bits (4237), Expect = 0.0 Identities = 1122/3033 (36%), Positives = 1507/3033 (49%), Gaps = 168/3033 (5%) Query: 15 AIIGYAARFPGAAS-AEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAG 73 AI+G R PG + + LL R+A++ +P RWD+ FDPDP GK R A Sbjct: 1580 AIVGVGLRLPGGVDDVDALFRLLEGERDAVAPIPASRWDVGAVFDPDPEAKGKTYVRHAA 1639 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 +D V FDA FFG+S RE R +DPQHR+L+ETAW+A+E + I P SL +S TGVFVG Sbjct: 1640 MLDRVDLFDAGFFGISPREARHVDPQHRLLLETAWQALEAATIVPASLRDSTTGVFVGAG 1699 Query: 134 THDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQ 193 DY + S + EAY A+GT+ + AAGR+++ LGLQGPA+++DTACSSSLVA+H Sbjct: 1700 ASDYAVLQSSA---EDAEAYAAMGTAASFAAGRLAFTLGLQGPALSIDTACSSSLVALHL 1756 Query: 194 ACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGV 253 ACQ+LR ECDLALA G V+ +P + S LAPDGR KTF A ADG+ RGEG V Sbjct: 1757 ACQSLRQGECDLALAAGVQVMASPEVFVILSRTRALAPDGRSKTFSANADGFGRGEGVVV 1816 Query: 254 VVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADV 313 + ++RL DA +G + AV+RG+A+N DGAS G+T PNG +QQ+V+ AL A L P DV Sbjct: 1817 LALERLRDARANGHPVLAVVRGTAVNHDGASSGITAPNGSSQQKVLRAALDDARLAPTDV 1876 Query: 314 GYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXX 373 +E HGTGTSLGDPIE QA V G GRAPE PL +G+ KTNIGHLE Sbjct: 1877 DVVECHGTGTSLGDPIEVQALAAVYGEGRAPERPLRLGAVKTNIGHLEFASGLAGVVKIV 1936 Query: 374 XXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRN--GKPRIAGVSSFGFAGTNA 431 L + TLP ++ +PHI W+ LP+ VV PW+R+ G PR AGVS+FG +GTNA Sbjct: 1937 ASLRHGTLPATIHTNPRNPHIDWDALPVRVVDAAEPWERSADGSPRRAGVSAFGLSGTNA 1996 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADV 491 HVI+EEAP P LSA++ AL A RD L P A L DV Sbjct: 1997 HVIVEEAPEPDAPKAARGALPLSGALPFVLSAKSDAALRAQAAALRDQLARTPDAALVDV 2056 Query: 492 SHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQG 551 + T R+ + RAA+ + + + L LA APG + A K A+LFTGQG Sbjct: 2057 AAALATTRSQFDHRAAIAASDHGALVAALEGLAAGVAAPGTFVAKG-AADKLAFLFTGQG 2115 Query: 552 SQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYA 611 +Q M R L+D PVF + + A + L++PL DV+F + S L T + Sbjct: 2116 AQRAAMGRGLYDAFPVFRDALDAVASHLDRELDRPLRDVLFAPK--GSELASLLDRTEFT 2173 Query: 612 QPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGS 671 QPALFA+E+ L RL ++WG PDV++GHSVG+ +AA VAGV + D L+A R RL + Sbjct: 2174 QPALFALEVALFRLVEAWGVTPDVLLGHSVGELAAAHVAGVLSLADACTLVAARARLMQA 2233 Query: 672 LPA--GGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLVADG 728 LPA G + T E L +AA N ++TV++G + A A G Sbjct: 2234 LPARDGAMVTVHATEAEVLAALEGRDGRAEIAAINAPSSTVIAGDVDAVLRVAAHFEARG 2293 Query: 729 VRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYW 788 + L SHAFHS +DP+LD F A+ L + P+ ++ N TG R YW Sbjct: 2294 RKATRLRVSHAFHSHHMDPMLDAFRRVAEGLTFHPPRIPIVSNVTGRLAADEIRSPD-YW 2352 Query: 789 RRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTA 848 RH R V FA + TL E+GP VL+A +A + + +LR A Sbjct: 2353 VRHVRSAVRFADGINTLEADGVSSFFELGPHGVLSALGESALANAQREVAFVPALRDGRA 2412 Query: 849 DHRQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLPTYPFEHRQFWFSDNRAIDRDTQTA 907 D +T A+++ + GH D+ AF P D + + LPTY F+ +FW RD Sbjct: 2413 DVDALTAALSSLHVRGHRVDWAAFFGPFDPQTVALPTYAFQRDRFWLDAPAGATRD---- 2468 Query: 908 SAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTL--RVLNKLAARHNQQRSTHVDP 965 A P R ++ G + L A ++ D + +L L+A + + Sbjct: 2469 EAAPAAPEDAAFWRAVDAGDVGALGATLNASGEDHLSALATLLPALSAWRRARDERSLVD 2528 Query: 966 DARYEIRWDXXXXXXXXXXXXXDWILV---GDDTAAVLEFADALTAGGHRHQIVALPGSD 1022 RY + W W+LV G + A E ALTA G + + ++ Sbjct: 2529 ALRYRVVWKPLTPTAARDVAGT-WLLVTLAGAEDALARELERALTARGAEVITMPIAPAE 2587 Query: 1023 ADEAQLVDTLRAA--SAGELY-VVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDA 1079 AD +L ++ A AGEL +V AA D L L RL +A D Sbjct: 2588 ADRVRLAVRVQGALADAGELRGIVSFAALDETTLATHTALPAG---LALTLRLVQALGDM 2644 Query: 1080 ELRSPIWLVTRDGQRVTDTDTVVPE-QSCLWGFGRAAALELPHIWGGLADLSGADTEWPR 1138 + +P+WLVTR +D + QS WG GR LE P WGGL D++ DT R Sbjct: 2645 GIEAPLWLVTRGAVSTGRSDRLASAAQSMTWGLGRVVGLEHPERWGGLVDVADGDTIDAR 2704 Query: 1139 LIARITS---PRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIG 1195 + R+ + RDGEDQ+ALR ++A RLVR + T LVTGG GA+G Sbjct: 2705 ALDRLVTLLASRDGEDQLALRPTGIFARRLVRAPLGDAPPARTYTARGTSLVTGGTGALG 2764 Query: 1196 LEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMT 1255 VA +LA GA H+VL SRR E V + DVAD VA L+ Sbjct: 2765 AHVARFLAGRGAEHLVLVSRRGEDAPGAGALRAELEALGARVTLAACDVADRASVAALLA 2824 Query: 1256 TVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFF 1315 + A+ P+ +VHA G + L+ D V V A KV GA HL E L D +LD F Sbjct: 2825 RLDAQGDPVRAVVHAGGVVAQAALASTDLDGVQAVVAAKVRGALHLHELLGD--RELDAF 2882 Query: 1316 VSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG-----MADAE 1370 V +S A VWG Q AY A NAFLD LA R G+TA S+ +G WA G ADA+ Sbjct: 2883 VLFASGAGVWGSGQQGAYAAGNAFLDALAEVRRAAGLTATSIAWGAWAGGGMLADHADAD 2942 Query: 1371 SRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRAFLSELE 1429 + L +RG+ ++PA A+A +A + G VA +DW+RF P + A R L +L Sbjct: 2943 AEVELRKRGLVPMAPALAIAALAGALDHGETAVTVASVDWARFAPAFASARPRPLLLDLP 3002 Query: 1430 S--ELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQR-KSLITNYLRNAVAEVTRVDADEI 1486 LVE L R + L+ + A + DA I Sbjct: 3003 EAQRAIEAPSAPAGADGASADRALVEALRPLSEADRARHLVELVVAETAAVLGHADASAI 3062 Query: 1487 RDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYL-----LVEVLG 1541 GFFDLG+DSL+AVEL R++ G ++P T+ DHP A Y+ L L Sbjct: 3063 DPHKGFFDLGLDSLVAVELLRKLRARTGVELPATVTFDHPSPHRLATYVREALPLDAPLA 3122 Query: 1542 LGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDRWD 1600 + T R +S+ A D+PIA+V + R PG D E W L G D + +P+DRWD Sbjct: 3123 PADATTAR-SSSAHAAIDEPIAIVGLGLRLPGGVEDREGLWSFLEQGRDGVGPIPKDRWD 3181 Query: 1601 IDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLE 1660 D YDPDP+ GK+Y R FFGISPREA ++PQ RL+LET W+ LE Sbjct: 3182 ADAIYDPDPEAKGKSYVREAALLDRVDLFDAAFFGISPREAKQVDPQHRLLLETAWQALE 3241 Query: 1661 RAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGF 1720 A P+ L+ + TGVF G+ ++YA L S ++ + + G + +GR+AF LG Sbjct: 3242 EATIVPASLKDTSTGVFVGIGLSDYA--LMQGSAEETDAYAAMGTLSSFAAGRLAFTLGL 3299 Query: 1721 EGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVG 1780 +GPA+++DTACSS+LVA+H ACQ+L+ G+CDLALAGGV V+ V SR R L+ G Sbjct: 3300 QGPALSIDTACSSSLVALHLACQSLRKGECDLALAGGVQVMTLAEPFVLLSRTRALAADG 3359 Query: 1781 RCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGG 1840 R KTF A ADGY R EG VL L+RL DA G RV AV+ ++VN DGASSG+T PNG Sbjct: 3360 RSKTFSAHADGYGRGEGVVVLALERLRDAEARGRRVLAVVRGTAVNHDGASSGITAPNGT 3419 Query: 1841 AQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSV 1900 +QQ+++ A L AGL+ ADVD +E HGTGT LGDPIEVQ PLL+G+V Sbjct: 3420 SQQKVLRAALGDAGLAPADVDVVECHGTGTALGDPIEVQALAAVYGEGRAAERPLLLGAV 3479 Query: 1901 KTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPW--Q 1958 K+NIGH E+ASG AG+ K+V +L+HG LP ++H +PH+ WDAL VRV+D W + Sbjct: 3480 KSNIGHLEAASGLAGVAKIVTALEHGALPATIHSRPRNPHVDWDALHVRVVDAAELWARR 3539 Query: 1959 TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV--LAL 2016 RRAGVS+FG +GTNAH ++EEAP TD+ P + L Sbjct: 3540 DEETPRRAGVSAFGLSGTNAHAIIEEAP------------RARRGAAATDEPPPAVPVVL 3587 Query: 2017 SARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXX 2076 SA+S AL A R ++ PG + DV + RSHFE+RAA+V + Sbjct: 3588 SAKSERALRAQAERLRAHVTGRPGDALVDVAASLATTRSHFEHRAAIVARDLGALEDALA 3647 Query: 2077 XXXXXXTPAGVVRGEHVHRPT---TAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEA 2133 +PAG V V R T A LFTGQG Q M R L+ VF Sbjct: 3648 GLAEGRSPAGTV----VSRTTGGKLALLFTGQGGQRAAMGRGLYGAFSVFRDAFDAACSY 3703 Query: 2134 VADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHS 2192 + L PL DV+FA E A LL T + Q +LFA+E+ L RL ++W + P V+LGHS Sbjct: 3704 LDRELEHPLRDVVFAPRGSELAALLDETLYTQTSLFALEVALFRLVEAWGVTPHVLLGHS 3763 Query: 2193 VGQYAAACVAGVFSLDDGARLMAERGRMFGSLP-EGGRMVAVFADAEHV----EQVAGEF 2247 +G+ AA VAGV SL+D L+A R R+ +LP MVAV A V + +AG Sbjct: 3764 IGELVAAHVAGVLSLEDACTLVAARARLMHALPRRDAAMVAVHACESEVLDALDAMAGLD 3823 Query: 2248 PRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXX 2306 R S+ A N P +TV++G E + + RFE G + + L SHAFHS LDP+L+ Sbjct: 3824 GRASIAAVNAPSSTVVAGDREAVLAVAARFEALGRKTSRLRVSHAFHSHHLDPMLEAFRR 3883 Query: 2307 XXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM 2366 P +P+V N TGA + A YW RH+R V+FA+ + + A G S + Sbjct: 3884 VAEGVRFEPPRIPIVSNVTGARASNDDLCSADYWVRHARGTVRFADGLEALRADGVSTFL 3943 Query: 2367 EIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR 2426 E+GP VL + A + +LR G D + AL + + GH D+ A Sbjct: 3944 ELGPHAVLCALGHETLESEAVA--FLPALRDGRDDVDTLTAALGALHARGHHVDWDAFFA 4001 Query: 2427 Q-PRRPVELPTYPFQRRRFW---PKASSIAVDGGTAAS--GILGSGKDLASGDTIYTSRL 2480 V LPTY FQR RFW PKA S +A + G+ DL G ++T + Sbjct: 4002 PFNAGRVALPTYAFQRERFWLDMPKAKSSRAAAADSAGRYPLAGTRLDLPDGSAVHTLDI 4061 Query: 2481 SVKSQPWLADHVIYGTVVVPGATYAAMALAAV-----GTPARLKDVFFYEPIILPEKASR 2535 +QP+LADH +YG +VVPGA + A+ LA +P L+DV F + E + Sbjct: 4062 GPGAQPYLADHSVYGRIVVPGAFHLAVLLAVAESHWPDSPLELRDVEFVRALTFEEPSET 4121 Query: 2536 -EVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDE 2594 V++ L PA GG F H+ + W+ +A T+ G+ P +A E Sbjct: 4122 VAVRVHLTPA-GGDGKGF--HATVATQTEGAWTTHATATL---GAAPPSALARHPRAAHE 4175 Query: 2595 VIERLERMRP-QDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSE 2653 + E R L +F + WGP W ++ GD VG + A Sbjct: 4176 PLAGDEPSRAVARLMASFEAFNVEWGPKWRWLRQTTHAGDRTGVG--YLAAPDGVPTDDA 4233 Query: 2654 PMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLR--------YGQ---------VTLA 2696 P+ L+D V + PL YG+ V Sbjct: 4234 PLPGGLVDNAFAVVGSAVTGLPAHDNRSTSNVPPLPFSIERLVWYGRAETPCWADFVMRG 4293 Query: 2697 EKMP---RRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGL 2753 E P R W R SE E G + I +RAP + L L Sbjct: 4294 EITPDADRYIGDITLWSREGASSEGASRE-------GTPIATIEGLAFRRAPADKFLPEL 4346 Query: 2754 GGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVL 2813 R LY L W E P ++ G W + G D L + + D D+ L + L Sbjct: 4347 ---PARNLYALTWPE--QPAASRPPRGRWALLGEDSLG--IATGIAADAYPDVDALRDAL 4399 Query: 2814 SQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKL---- 2869 RGA V C T L+S+VH A ++ L Sbjct: 4400 ----GRGAPCPDTVAVCLATAHGPSDTDE----------TELVSSVHTAAARALALLNAW 4445 Query: 2870 -------PGGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSS 2921 L ++T+ VA +GE V D AALWG R+ E LVD DGS Sbjct: 4446 LSDERLASSTLVLLTQRAVATCAGEDVLDLASAALWGLVRSAQAENRDRAILLVDLDGSD 4505 Query: 2922 EAVDXXXXXXXXP-GIQEPEIAVRQGKLLASRL 2953 + EP++A+R G+ LA RL Sbjct: 4506 ASRRALPYAVGGALDDAEPQLALRDGRRLAPRL 4538 Score = 1518 bits (3930), Expect = 0.0 Identities = 985/2490 (39%), Positives = 1300/2490 (52%), Gaps = 117/2490 (4%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAG 73 AI+G R PG + W L +GR+AI+ +P RW+ + +DPDP GK R A Sbjct: 27 AIVGLGLRLPGGIHDRDTLWTFLEEGRDAIAPIPASRWNADATYDPDPDAVGKSYVRDAA 86 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 +D V FDA FFG+S RE + +DPQHR+L+ET+W+A+E +GI P SL +S TGVFVG Sbjct: 87 MLDRVDLFDADFFGISPREAKYVDPQHRLLLETSWQALEDAGIVPASLRDSKTGVFVGTG 146 Query: 134 THDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQ 193 DY + SD EAY +G ++ AAGR+++ LGLQGPA+++DTACSSSLVA+H Sbjct: 147 ASDYAFLQSDR---DASEAYAFMGMISSFAAGRLAFTLGLQGPALSIDTACSSSLVALHL 203 Query: 194 ACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGV 253 ACQ+LR ECDLAL G V+ +P + S LA DGR KTF A ADGY RGEG V Sbjct: 204 ACQSLRQGECDLALVAGVQVMSSPEVFVLLSRTRALASDGRSKTFSANADGYGRGEGVVV 263 Query: 254 VVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADV 313 + V+RL DA G I AVIRGSA+N DG S G+TVPNG AQQ+V+ AL A L PADV Sbjct: 264 LAVERLRDARAKGRPILAVIRGSAVNHDGTSSGITVPNGPAQQKVLRAALDDARLVPADV 323 Query: 314 GYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXX 373 +E HGTGTS+GDPIE A V G GR + PL +G+ KTNIGHLE Sbjct: 324 DVVECHGTGTSIGDPIEVNALAAVYGEGRPKDRPLFLGALKTNIGHLEFASGLAGVAKMV 383 Query: 374 XXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR--NGKPRIAGVSSFGFAGTNA 431 + + TLP L+ +P + W+ LP+ VV PW R +G PR AGV++ G +GTNA Sbjct: 384 ASMRHATLPATLHTSPLNPLVDWDALPVRVVDAARPWTRRDDGAPRRAGVTAIGLSGTNA 443 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADV 491 HVI+EEAPA P T + VL LS +T EAL A L P ARL D+ Sbjct: 444 HVIVEEAPAEPEPTTPDAAPALPAVPVL-LSGKTDEALRAQAARLHAHLAGRPDARLVDI 502 Query: 492 SHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQG 551 + + T R H ++RAA+V R+ + L ALA PG V + A + ++F GQG Sbjct: 503 AASLATTRTHFDRRAAVVAADRDELLGALDALARGEAGPGSVVASAIPAGRVVFVFPGQG 562 Query: 552 SQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYA 611 SQ+ GMAR L + VF + + C A+A + L V+ DGD + L Sbjct: 563 SQWVGMARALLASSVVFRDEIAACERALAPHVAWSLGAVLRG----DGDEATLLGRVDVV 618 Query: 612 QPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGS 671 QP LFAV + LA LW+S G PD VVGHS G+ +AA VAG +ED A+++A R R Sbjct: 619 QPVLFAVMVALAALWRSIGVTPDAVVGHSQGEIAAAYVAGALSLEDAAKVVALRARALTK 678 Query: 672 LPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGAN-TVLSGPAKDLESAVATLVADGV 729 + G MAAV A + RL ++++AA N T+++G +++ V L A + Sbjct: 679 IAGRGAMAAVELGARDTEARLAPFGDAIAIAAINSPRATLVAGDTDAIDALVRDLEAAQI 738 Query: 730 RCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWR 789 + +A HSA ++ I + + +E R L TG+ L S RLD A+W Sbjct: 739 FARKVRVDYASHSAHVEAIERELLADLAGIEPRAGAVPLYSAVTGAKLDGS-RLDAAHWF 797 Query: 790 RHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTAD 849 R+ R V F + R L D R +E+ P PVL V++SLR D Sbjct: 798 RNLRSTVRFEDATRALHDDGHRFFVEVSPHPVLALALDETLSSIGGDAAVVSSLRRDEGD 857 Query: 850 HRQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLPTYPFEHRQFWFSDNRAIDRDTQTAS 908 + + +A GH D+ AF P AR++ LPTY F+ +FW A D + Sbjct: 858 LERFLLSAGELHARGHAIDWGAFFAPLGARRVTLPTYAFQRERFWLDAGDASDDEDAAPG 917 Query: 909 AGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLR-----VLNKLAARHNQQRSTHV 963 A + T R +E G + AAL D V + R ++ L+A +R Sbjct: 918 ASA---EETAFWRAIERGDV---AALSDALHVADSGRRSALESLMPALSAWRRSRREQST 971 Query: 964 DPDARYEIRWDXXXXXXXXXXXXXDWILVG-----DDTAAVLEFADALTAGGHRHQIVAL 1018 RY + W W++V D A+ L A ALT G +AL Sbjct: 972 VGAWRYRVEW-RPVSAASRGDVAGTWLVVAPAGVASDLASAL--AAALTERGADVVPLAL 1028 Query: 1019 PGSDADEAQLVDTLRAASAGE--------LYVVHIAAGDGAAAPMRDLLRVQHRTLGGLR 1070 SD LR A AG L + A DG A L R Sbjct: 1029 EASDITAHDAASRLRDAIAGRPAIRGVLTLTPLDTAPLDGRPAVPAGLARSL-------- 1080 Query: 1071 RLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADL 1129 L +A + + +PIW+VTR + +D + P Q+ WG GR +LE P WGGL DL Sbjct: 1081 ALVQALAELAIEAPIWIVTRGAVAIGRSDRIESPVQAMAWGLGRVVSLEQPERWGGLVDL 1140 Query: 1130 SGAD-------TEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVRED 1182 A T RL+A + S R+GED++ALR ++A RL R D P E Sbjct: 1141 PRAHADGALDATAIERLVAALGS-REGEDELALRPTGLFARRLAR--APLGDAPAQRFEP 1197 Query: 1183 R-TYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVIT 1241 R T LVTGG GA+G VA +LA HGA H+VL SRR + V + Sbjct: 1198 RGTVLVTGGTGALGAHVARWLARHGAAHLVLASRRGAAAPGAEALRAELTELGARVTIAA 1257 Query: 1242 ADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHL 1301 DVAD + L + AE PL I H AG I L L ++ V GK A L Sbjct: 1258 CDVADRAAIEELFAALPAE-EPLTAIFHTAGVIDDGVLGSLTPERLETVLHGKADAARTL 1316 Query: 1302 SEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGP 1361 E LT R DL FV SS A V+G GQ +Y AANAFLD LA R G+ A SV +G Sbjct: 1317 HE-LTKTR-DLAAFVLFSSAAGVFGNAGQASYAAANAFLDALAEERRALGLRATSVAWGA 1374 Query: 1362 WA-AGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQA 1419 WA AGM + L + G + P A+A +A + V +A IDW+RF P Y A Sbjct: 1375 WAGAGMLTFDVAQGLRRGGFAAMEPEIAVAALASALDRDETHVTIASIDWARFAPSYASA 1434 Query: 1420 GRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT 1479 +R +++L + + + + L++ L A + Sbjct: 1435 RQRPLVADLPDARRALDAQPSASTEHDETALVATLRALSGEARLRHLVSLVLAQTAAVLG 1494 Query: 1480 RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLL--V 1537 D + + GFFDLG+DSLMAVELRRR+++ G +P T+ D P A +LL + Sbjct: 1495 HADRSRLDPQRGFFDLGLDSLMAVELRRRLQKATGVKLPATITFDRPSPHRLAGFLLDAL 1554 Query: 1538 EVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAPDP-ESFWELLAGGVDAIREVPE 1596 + G T+ R + +D+PIA+V V R PG D ++ + LL G DA+ +P Sbjct: 1555 PLGGAAPSTDARPRAARADASDEPIAIVGVGLRLPGGVDDVDALFRLLEGERDAVAPIPA 1614 Query: 1597 DRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVW 1656 RWD+ +DPDP+ GKTY R FFGISPREA ++PQ RL+LET W Sbjct: 1615 SRWDVGAVFDPDPEAKGKTYVRHAAMLDRVDLFDAGFFGISPREARHVDPQHRLLLETAW 1674 Query: 1657 EGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAF 1716 + LE A P+ LR S TGVF G A++YA L S S + E + G A + +GR+AF Sbjct: 1675 QALEAATIVPASLRDSTTGVFVGAGASDYAVLQS--SAEDAEAYAAMGTAASFAAGRLAF 1732 Query: 1717 ALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARML 1776 LG +GPA+++DTACSS+LVA+H ACQ+L+ G+CDLALA GV V+ SP V SR R L Sbjct: 1733 TLGLQGPALSIDTACSSSLVALHLACQSLRQGECDLALAAGVQVMASPEVFVILSRTRAL 1792 Query: 1777 SPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTV 1836 +P GR KTF A+ADG+ R EG VL L+RL DA +G V AV+ ++VN DGASSG+T Sbjct: 1793 APDGRSKTFSANADGFGRGEGVVVLALERLRDARANGHPVLAVVRGTAVNHDGASSGITA 1852 Query: 1837 PNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLL 1896 PNG +QQ+++ A L A L+ DVD +E HGTGT LGDPIEVQ PL Sbjct: 1853 PNGSSQQKVLRAALDDARLAPTDVDVVECHGTGTSLGDPIEVQALAAVYGEGRAPERPLR 1912 Query: 1897 MGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVP 1956 +G+VKTNIGH E ASG AG++K+V SL+HG LP ++H +PHI WDALPVRV+D P Sbjct: 1913 LGAVKTNIGHLEFASGLAGVVKIVASLRHGTLPATIHTNPRNPHIDWDALPVRVVDAAEP 1972 Query: 1957 WQ--TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV- 2013 W+ +G RRAGVS+FG +GTNAHV+VEEAP D+P+ Sbjct: 1973 WERSADGSPRRAGVSAFGLSGTNAHVIVEEAP--------------------EPDAPKAA 2012 Query: 2014 -----------LALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAA 2062 LSA+S AL A D L+ TP + DV RS F++RAA Sbjct: 2013 RGALPLSGALPFVLSAKSDAALRAQAAALRDQLARTPDAALVDVAAALATTRSQFDHRAA 2072 Query: 2063 LVVDSVXXXXXXXXXXXXXXTPAG--VVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQ 2120 + G V +G A+LFTGQG+Q M R L+D Sbjct: 2073 IAASDHGALVAALEGLAAGVAAPGTFVAKGA---ADKLAFLFTGQGAQRAAMGRGLYDAF 2129 Query: 2121 PVFAQTVRQCAEAVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQ 2179 PVF + A + L RPL DVLFA E A LL T F QPALFA+E+ L RL + Sbjct: 2130 PVFRDALDAVASHLDRELDRPLRDVLFAPKGSELASLLDRTEFTQPALFALEVALFRLVE 2189 Query: 2180 SWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLP-EGGRMVAVFA-DA 2237 +W + PDV+LGHSVG+ AAA VAGV SL D L+A R R+ +LP G MV V A +A Sbjct: 2190 AWGVTPDVLLGHSVGELAAAHVAGVLSLADACTLVAARARLMQALPARDGAMVTVHATEA 2249 Query: 2238 EHVEQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSEL 2296 E + + G R + A N P +TV++G + + + FE G + T L SHAFHS Sbjct: 2250 EVLAALEGRDGRAEIAAINAPSSTVIAGDVDAVLRVAAHFEARGRKATRLRVSHAFHSHH 2309 Query: 2297 LDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRT 2356 +DP+LD P +P+V N TG L YW RH R V+FA+ + T Sbjct: 2310 MDPMLDAFRRVAEGLTFHPPRIPIVSNVTGR-LAADEIRSPDYWVRHVRSAVRFADGINT 2368 Query: 2357 VAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGG 2416 + A G S E+GP VL+ V +LR G AD + AL+S +V G Sbjct: 2369 LEADGVSSFFELGPHGVLSALGESALANAQREVAFVPALRDGRADVDALTAALSSLHVRG 2428 Query: 2417 HRPDFAAVHRQ-PRRPVELPTYPFQRRRFW 2445 HR D+AA + V LPTY FQR RFW Sbjct: 2429 HRVDWAAFFGPFDPQTVALPTYAFQRDRFW 2458 Score = 584 bits (1506), Expect = e-164 Identities = 362/915 (39%), Positives = 485/915 (53%), Gaps = 28/915 (3%) Query: 1557 RTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKT 1615 R +PIA+V + R PG D ++ W L G DAI +P RW+ D YDPDPD GK+ Sbjct: 21 RRHEPIAIVGLGLRLPGGIHDRDTLWTFLEEGRDAIAPIPASRWNADATYDPDPDAVGKS 80 Query: 1616 YTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTG 1675 Y R +FFGISPREA +++PQ RL+LET W+ LE AG P+ LR S+TG Sbjct: 81 YVRDAAMLDRVDLFDADFFGISPREAKYVDPQHRLLLETSWQALEDAGIVPASLRDSKTG 140 Query: 1676 VFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSAL 1735 VF G A++YA L S D E + G + +GR+AF LG +GPA+++DTACSS+L Sbjct: 141 VFVGTGASDYAFLQSDR--DASEAYAFMGMISSFAAGRLAFTLGLQGPALSIDTACSSSL 198 Query: 1736 VAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRS 1795 VA+H ACQ+L+ G+CDLAL GV V+ SP V SR R L+ GR KTF A+ADGY R Sbjct: 199 VALHLACQSLRQGECDLALVAGVQVMSSPEVFVLLSRTRALASDGRSKTFSANADGYGRG 258 Query: 1796 EGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGL 1855 EG VL ++RL DA G + AVI S+VN DG SSG+TVPNG AQQ+++ A L A L Sbjct: 259 EGVVVLAVERLRDARAKGRPILAVIRGSAVNHDGTSSGITVPNGPAQQKVLRAALDDARL 318 Query: 1856 SGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAG 1915 ADVD +E HGTGT +GDPIEV PL +G++KTNIGH E ASG AG Sbjct: 319 VPADVDVVECHGTGTSIGDPIEVNALAAVYGEGRPKDRPLFLGALKTNIGHLEFASGLAG 378 Query: 1916 LIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPW--QTNGRVRRAGVSSFGF 1973 + K+V S++H LP +LH +P + WDALPVRV+D PW + +G RRAGV++ G Sbjct: 379 VAKMVASMRHATLPATLHTSPLNPLVDWDALPVRVVDAARPWTRRDDGAPRRAGVTAIGL 438 Query: 1974 TGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLA----LSARSPEALVELAR 2029 +GTNAHV+VEEAP + D +P + A LS ++ EAL A Sbjct: 439 SGTNAHVIVEEAPAEPEPTTP-------------DAAPALPAVPVLLSGKTDEALRAQAA 485 Query: 2030 RYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVR 2089 R L+ P + D+ + R+HF+ RAA+V G V Sbjct: 486 RLHAHLAGRPDARLVDIAASLATTRTHFDRRAAVVAADRDELLGALDALARGEAGPGSVV 545 Query: 2090 GEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFAT 2149 + ++F GQGSQ+ GMAR L + VF + C A+A + L VL Sbjct: 546 ASAIPAGRVVFVFPGQGSQWVGMARALLASSVVFRDEIAACERALAPHVAWSLGAVLRG- 604 Query: 2150 DRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDD 2209 D + A LL QP LFAV + LA LW+S + PD V+GHS G+ AAA VAG SL+D Sbjct: 605 DGDEATLLGRVDVVQPVLFAVMVALAALWRSIGVTPDAVVGHSQGEIAAAYVAGALSLED 664 Query: 2210 GARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF-PRVSVGAYNGPN-TVLSGPGE 2267 A+++A R R + G M AV A E F +++ A N P T+++G + Sbjct: 665 AAKVVALRARALTKIAGRGAMAAVELGARDTEARLAPFGDAIAIAAINSPRATLVAGDTD 724 Query: 2268 DLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGA 2327 ++ +V E I + +A HS ++ + +PL TGA Sbjct: 725 AIDALVRDLEAAQIFARKVRVDYASHSAHVEAIERELLADLAGIEPRAGAVPLYSAVTGA 784 Query: 2328 VLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMA 2387 L G LDA +W R+ R V+F ++ R + G +E+ P PVL A + Sbjct: 785 KLDGSR-LDAAHWFRNLRSTVRFEDATRALHDDGHRFFVEVSPHPVLALALDETLSSIGG 843 Query: 2388 APRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWP 2446 V+SLR+ D + + + GH D+ A R V LPTY FQR RFW Sbjct: 844 DAAVVSSLRRDEGDLERFLLSAGELHARGHAIDWGAFFAPLGARRVTLPTYAFQRERFWL 903 Query: 2447 KASSIAVDGGTAASG 2461 A A D AA G Sbjct: 904 DAGD-ASDDEDAAPG 917 Score = 174 bits (442), Expect = 2e-40 Identities = 125/364 (34%), Positives = 168/364 (46%), Gaps = 19/364 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA GA +VL SRR D A+ E R+ A DV Sbjct: 2755 LVTGGTGALGAHVARFLAGRGAEHLVLVSRRGEDAPGAGALRAELEALGARVTLAACDVA 2814 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D A VA LLAR+ A+ P+ + H GV+ A L++ + + + +A K GA H Sbjct: 2815 DRASVAALLARLDAQGDPVRAVVHAGGVVAQAALASTDLDGVQAVVAAKVRGALHLHELL 2874 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 Q YA NA LD L RRA GL AT I +G W GGM Sbjct: 2875 GDRELDAFVLFASGAGVWGSGQQGAYAAGNAFLDALAEVRRAAGLTATSIAWGAWAGGGM 2934 Query: 3478 ASSEA---ATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 + A A + +GL+P+ P+ A+ ALA + +G TV +W R A SARP Sbjct: 2935 LADHADADAEVELRKRGLVPMAPALAIAALAGALDHGETAVTVASVDWARFAPAFASARP 2994 Query: 3535 PILDLVLPSA------------AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL 3582 L L LP A A A+ D L++ L + RA + E + E L Sbjct: 2995 RPLLLDLPEAQRAIEAPSAPAGADGASADRALVEALRPLSEADRARHLVELVVAETAAVL 3054 Query: 3583 RLASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV 3640 A A F DLG DSL+A+EL +L ++ G + AT FD+P+ LA Y+ Sbjct: 3055 GHADASAIDPHKGFFDLGLDSLVAVELLRKLRARTG--VELPATVTFDHPSPHRLATYVR 3112 Query: 3641 GQLP 3644 LP Sbjct: 3113 EALP 3116 Score = 160 bits (404), Expect = 5e-36 Identities = 130/370 (35%), Positives = 171/370 (46%), Gaps = 24/370 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRD---PDESAQRAIDEITERHKCRIHTYAA 3354 L+TGG GA+G H A +LA+ GA +VL SRR P A RA E+TE R+ A Sbjct: 1202 LVTGGTGALGAHVARWLARHGAAHLVLASRRGAAAPGAEALRA--ELTEL-GARVTIAAC 1258 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXX 3414 DV D A + +L A + AE PL I H AGV+DD +L + PER T L KA A Sbjct: 1259 DVADRAAIEELFAALPAE-EPLTAIFHTAGVIDDGVLGSLTPERLETVLHGKADAARTLH 1317 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQA+YA ANA LD L +RRA GL AT + +G W Sbjct: 1318 ELTKTRDLAAFVLFSSAAGVFGNAGQASYAAANAFLDALAEERRALGLRATSVAWGAWAG 1377 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA-- 3532 GM + + A + G ++P A+ ALA + T+ +W R A SA Sbjct: 1378 AGMLTFDVA-QGLRRGGFAAMEPEIAVAALASALDRDETHVTIASIDWARFAPSYASARQ 1436 Query: 3533 RPPILDL--------VLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 RP + DL PSA+ E ++ L+ L + R + + + L Sbjct: 1437 RPLVADLPDARRALDAQPSASTE-HDETALVATLRALSGEARLRHLVSLVLAQTAAVLGH 1495 Query: 3585 ASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 A + F DLG DSLMA+ELR RL G K + AT FD P+ LA +L+ Sbjct: 1496 ADRSRLDPQRGFFDLGLDSLMAVELRRRLQKATGVK--LPATITFDRPSPHRLAGFLLDA 1553 Query: 3643 LP-DAEAPET 3651 LP AP T Sbjct: 1554 LPLGGAAPST 1563 Score = 146 bits (368), Expect = 7e-32 Identities = 162/574 (28%), Positives = 236/574 (41%), Gaps = 70/574 (12%) Query: 989 WILVGDDTAAVLE------------FADALTAGGHRHQIVAL------PGSDADEAQLVD 1030 W L+G+D+ + DAL G VA+ SD DE +LV Sbjct: 4370 WALLGEDSLGIATGIAADAYPDVDALRDALGRGAPCPDTVAVCLATAHGPSDTDETELVS 4429 Query: 1031 TLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTR 1090 ++ A+A L +++ D A +L Q + T Sbjct: 4430 SVHTAAARALALLNAWLSDERLASSTLVLLTQRA----------------------VATC 4467 Query: 1091 DGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRD-G 1149 G+ V D + + LWG R+A E L DL G+D L + D Sbjct: 4468 AGEDVLDLAS-----AALWGLVRSAQAENRDRAILLVDLDGSDASRRALPYAVGGALDDA 4522 Query: 1150 EDQIALRGDAVYAPRLVRRTG----------EPSDTPLPVREDRTYLVTGGLGAIGLEVA 1199 E Q+ALR APRL R S TP + + T LVTGG G +G VA Sbjct: 4523 EPQLALRDGRRLAPRLARVAAPTAATANAATSTSATPRALDPEGTVLVTGGTGTLGALVA 4582 Query: 1200 GYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVA 1258 L HG H+VL SRR P + V + AD A+ +AR++ + Sbjct: 4583 RRLVERHGVKHLVLLSRRGPDAPGATDLAAELQARGASVVLAAADAAEPAALARVLLAIP 4642 Query: 1259 AELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVST 1318 + P L +VHAAG + LS + A + V KV A +L E + L FV Sbjct: 4643 HDRP-LTAVVHAAGTLDDGVLSSMTPARLSAVLRAKVDAAVNLDEQTR--HSPLRAFVLF 4699 Query: 1319 SSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA--AGMADAESRA--- 1373 SS++ V G Q+ Y AANAFLD LA R RG+ AV++++G WA +G+ +A Sbjct: 4700 SSLSGVLGSPAQSNYAAANAFLDALAHRRAARGLPAVALDWGYWAQTSGLTKHLEQADLR 4759 Query: 1374 RLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELX 1433 R+ + G+R L+ EALA +A +V + F + A + L + Sbjct: 4760 RIARGGLRPLASDEALALFDLALAQDAPCLVP----AAFDADALRKSGDALSALLRGLVA 4815 Query: 1434 XXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDAD-EIRDEAGF 1492 L +L +R ++ + +R VA V V + +I Sbjct: 4816 GPRARAQRASGAGAASALKLRLASLAPLERHRMLLDVVRADVATVLGVASPLDIEPGRPL 4875 Query: 1493 FDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHP 1526 +LG+DSLMA+ELR R+ G + TL+ DHP Sbjct: 4876 QELGLDSLMAIELRNRLAAATGLRLSATLLFDHP 4909 Score = 125 bits (313), Expect = 2e-25 Identities = 114/365 (31%), Positives = 162/365 (44%), Gaps = 20/365 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TGG G +G A L + G +VL SRR PD + + + AAD Sbjct: 4569 LVTGGTGTLGALVARRLVERHGVKHLVLLSRRGPDAPGATDLAAELQARGASVVLAAADA 4628 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 + A +A +L I + P L + H AG LDD +LS+ P R L K A + Sbjct: 4629 AEPAALARVLLAIPHDRP-LTAVVHAAGTLDDGVLSSMTPARLSAVLRAKVDAAVNLDEQ 4687 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ-G 3475 P Q+NYA ANA LD L +R A+GL A +++G W Q Sbjct: 4688 TRHSPLRAFVLFSSLSGVLGSPAQSNYAAANAFLDALAHRRAARGLPAVALDWGYWAQTS 4747 Query: 3476 GMAS--SEAATANITAQGLIPL--DPSAALHAL-----AEVIANGSGQATVLKANWQRAA 3526 G+ +A I GL PL D + AL L A + + A L+ + + Sbjct: 4748 GLTKHLEQADLRRIARGGLRPLASDEALALFDLALAQDAPCLVPAAFDADALRKSGDALS 4807 Query: 3527 KVL-GSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA 3585 +L G P S AG A S L +L + +R + + ++ +V L +A Sbjct: 4808 ALLRGLVAGPRARAQRASGAGAA---SALKLRLASLAPLERHRMLLDVVRADVATVLGVA 4864 Query: 3586 SP--PAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 SP +LG DSLMAIELRNRL + G ++AT +FD+PT LA+ + G+L Sbjct: 4865 SPLDIEPGRPLQELGLDSLMAIELRNRLAAATG--LRLSATLLFDHPTPEALAKLISGKL 4922 Query: 3644 PDAEA 3648 EA Sbjct: 4923 LHDEA 4927 Score = 41.2 bits (95), Expect = 3.1 Identities = 55/209 (26%), Positives = 75/209 (35%), Gaps = 20/209 (9%) Query: 2762 YTLGWHEVPPPPSADDAVGTWLI---AGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHA 2818 Y + W V S D GTWL+ AG A +R D+ L S A Sbjct: 977 YRVEWRPVSAA-SRGDVAGTWLVVAPAGVASDLASALAAALTERGADVVPLALEASDITA 1035 Query: 2819 RGAGF---SGVVWRCATPG----RKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPG 2871 A + R A G + L+ V A +++ P Sbjct: 1036 HDAASRLRDAIAGRPAIRGVLTLTPLDTAPLDGRPAVPAGLARSLALVQALAELAIEAP- 1094 Query: 2872 GLWIVTEHGVACESGEPVD-PVQAALWGFGRTTINEEPALHCRLVD-----CDGSSEAVD 2925 +WIVT VA + ++ PVQA WG GR E+P LVD DG+ +A Sbjct: 1095 -IWIVTRGAVAIGRSDRIESPVQAMAWGLGRVVSLEQPERWGGLVDLPRAHADGALDATA 1153 Query: 2926 XXXXXXXXPGIQ-EPEIAVRQGKLLASRL 2953 + E E+A+R L A RL Sbjct: 1154 IERLVAALGSREGEDELALRPTGLFARRL 1182 >tr|C9YYI1|C9YYI1_STRSW Tax_Id=680198 SubName: Full=Putative type I polyketide synthase;[Streptomyces scabies] Length = 4970 Score = 1628 bits (4215), Expect = 0.0 Identities = 1115/3031 (36%), Positives = 1533/3031 (50%), Gaps = 171/3031 (5%) Query: 2 VSAEHPIEPTPSFAIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDP 59 V A P + AI+G + R+PG + E+ W L+ +GR+ IS +P DR WD++ +D Sbjct: 1573 VPAHVPADADDPIAIVGMSCRYPGDVRTPEDLWRLVAEGRDVISALPADRGWDLDGLYDT 1632 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 DP PG + GF+ D FD FFG+S RE MDPQ R+L+ET+W A+E +GI P Sbjct: 1633 DPDRPGTTYSSEGGFLYDAGQFDPAFFGISPREALAMDPQQRLLLETSWEALERAGIDPA 1692 Query: 120 SLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVA 179 SL GVF G A Y G++ E+E ++ G S + +GRI+Y LGL+GPAV Sbjct: 1693 SLRGGQVGVFAGAAYQGYGGLSD---VPEEVEGHLIAGISTSILSGRIAYTLGLEGPAVT 1749 Query: 180 VDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFD 239 VDTACSSSLVA+H A QALR EC LALAGG V+ TP + FS LA DGRCK+F Sbjct: 1750 VDTACSSSLVAVHLAAQALRSGECSLALAGGVTVMGTPLSFTGFSRQRGLAADGRCKSFG 1809 Query: 240 AAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI 299 A ADG+ EG G+++++RL DA R+G + A++RGSA+NQDGAS GLT P+G+AQQRVI Sbjct: 1810 AGADGFGMAEGAGLLLLERLSDARRNGHPVLALVRGSAVNQDGASNGLTAPSGLAQQRVI 1869 Query: 300 ADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGH 359 AL AG+ A+V +EAHGTGT LGDPIEAQA G R + PLL+GS K+NIGH Sbjct: 1870 RSALAGAGVPSAEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPADRPLLLGSLKSNIGH 1929 Query: 360 LEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIA 419 + + +E LP+ L+ E P+P++ W +E++ E PW RNG PR A Sbjct: 1930 SQAAAGVAGIIKMVQAMRHEELPRTLHAEEPTPNVDWSVGAVELLTEPRPWTRNGHPRRA 1989 Query: 420 GVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYR 477 GVSSFG +GTNAHVI+EE G A P E + +P LS RTPEAL A Sbjct: 1990 GVSSFGLSGTNAHVIIEEPH--GEEAGEAP-EGNAPVAAVPWLLSGRTPEALREQAARLH 2046 Query: 478 DWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGES 537 L P+ R DV T TAR+ E RA +V + + + L ALA + P +V G Sbjct: 2047 ARLTDRPELRPHDVGLTLATARSAFEHRAVVVGADQATLLTGLAALAAGQDDPAVVHGTV 2106 Query: 538 HEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADEL 597 +T ++F GQGSQ+ GMA L D+ PVFAE V +C A++ ++ L DV+ Sbjct: 2107 ATPGRTVFVFPGQGSQWAGMAVGLLDSAPVFAERVAQCERALSPYVDWSLTDVL-----R 2161 Query: 598 DGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVED 657 G PL QP LF+V + LA LW+S G EP V+GHS G+ +AA VAG +ED Sbjct: 2162 GGPDSPPLDRVDVVQPVLFSVMVSLAALWRSHGVEPSAVIGHSQGEIAAAVVAGALSLED 2221 Query: 658 GARLIAERGRLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNG-ANTVLSGPAK 715 GAR++A R R+ +L G M V +R ER+ LSVAA NG A +SG + Sbjct: 2222 GARIVALRSRILTTLVDRGAMLFVALPDDRVRERMAPWDGRLSVAAVNGPAAVTVSGDPE 2281 Query: 716 DLESAVATLVADGVRCDWL--DTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRT 773 LE L DGV W+ + A HS +D + + + R T Sbjct: 2282 ALEEFGDRLSEDGVM-RWMIPGVTFAGHSPQVDGLRRELLDALAGVTPRRTDVAFYSTVT 2340 Query: 774 GSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDP 833 G AL +T LD YW R+ R+PVEF +++ L D +E+ P PVL + Sbjct: 2341 GGALD-TTALDTEYWYRNLREPVEFHRALAALVDAGHDTFVEVSPHPVLAVWVEKSLEAA 2399 Query: 834 ATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQF 892 V +L + A+A + G D+RA F DAR ++LPTY F+ R++ Sbjct: 2400 DVAGLVTGTLHTDDGGPARFLTALAGPHVHGVPVDWRAVFAGTDARPVELPTYAFQRRRY 2459 Query: 893 WFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALI---DGETVDEQTLR-VL 948 W A+ A G P T +E + +AA + D + +L VL Sbjct: 2460 WLEPTAAL-----AAGEGGAQPADTAFWDAVERHDLTAVAAALNLPDADATARASLGGVL 2514 Query: 949 NKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTA 1008 LA +R RY++ + W +V AA + Sbjct: 2515 PALADWQRGRRGRTTIDGWRYQVTFKPLHLTPGTPALTGTWWVVVPAGAAGHPVVEGALR 2574 Query: 1009 GGHRHQIVALP----GSDADEAQLVDTLRAASAGELYVVHIAA------GDGAAAPMRDL 1058 RH A+P + D A L L AA+A + V+ + A DG A P Sbjct: 2575 ALERHGATAVPVEIGTTGTDRAGLAARLGAATAPDGGVLSLLALAEQPYADGTALPTGLA 2634 Query: 1059 LRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAAL 1117 L L +A DA + +P+W T V +D + P Q+ LWG G A + Sbjct: 2635 LTTT---------LLQALGDAGINAPLWSATCGAVSVGRSDALTAPAQATLWGLGAVAGV 2685 Query: 1118 ELPHIWGGLADL-SGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTP 1176 E P W G+ DL S D +A + + DGEDQIA+R VY RLVR T Sbjct: 2686 EYPERWAGMLDLPSDLDERAGVRLAAVLAGLDGEDQIAIRPSGVYGRRLVRARPAEETTA 2745 Query: 1177 LPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACD 1236 D T L+TGG GA+G VA LA GA H++LT RR P + Sbjct: 2746 DAFDPDGTVLITGGTGALGAHVARRLARSGARHLLLTGRRGPDTPGAAELVAELAGLGAE 2805 Query: 1237 VRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVW 1296 V D AD +A L+ + + P L +VHAAG + L L V K+ Sbjct: 2806 TTVAACDAADRDALATLLADIPEDRP-LRTVVHAAGLLDDGVLDTLTPERAAGVLRPKMD 2864 Query: 1297 GAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVS 1356 A +L DL DL FV SS+A GG GQ +Y AANAFLD LA + R G+ A S Sbjct: 2865 AALNLDALTRDL--DLTAFVLFSSLAGTLGGTGQGSYAAANAFLDALAEQRRSLGLPATS 2922 Query: 1357 VNFGPWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPL 1415 V +G WA A +R RL + G+ + P A+ + + + V+ W RF P Sbjct: 2923 VAWGLWAGDSAADSARERLVRNGLPPMDPELAVTALEQAMGRAEPRLVLCDFAWDRFAPA 2982 Query: 1416 YQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAV 1475 Y A L +L ++ L +L Q+R+ +T + V Sbjct: 2983 YTALRPSAALRDLP-DVRDVLAATGADRQETEADSLAARLAALSPQERQEELTRLVATEV 3041 Query: 1476 AEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADY 1534 A V D I + F DLG DSL AV+LR R+ + G + VTLV DHP ++ D+ Sbjct: 3042 AAVLGHPDPAGIDPDRVFKDLGFDSLTAVDLRNRLSEATGLRLSVTLVFDHPTVTALVDH 3101 Query: 1535 LLVEVLGLGE-QTNVRQASTVTART----DDPIAVVAVSCRFPGA-PDPESFWELLAGGV 1588 + E+ G QT+V ++ A+ DD IAVVA+SCR+PG PE W L+ G Sbjct: 3102 VRSELGGTAPAQTSVPAPASSPAQAAVADDDAIAVVAMSCRYPGGVTTPEDLWRLVTSGS 3161 Query: 1589 DAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQ 1647 DAI E P R WD+DE YDPDP+ G+TY R P FFGISPREA+ I+PQ Sbjct: 3162 DAITEFPTGRGWDLDELYDPDPEKLGRTYARHGGFLHDADHFDPAFFGISPREALAIDPQ 3221 Query: 1648 QRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNAL 1707 QRL+LE WE ERAG P L+GSR GVF G + +Y + + ++ E + G+A Sbjct: 3222 QRLLLEISWEAFERAGIDPVSLKGSRAGVFVGSSYRDYGSRVQ-QPTEETEGYLGIGSAG 3280 Query: 1708 NAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTV 1767 + SGR+A+ LG EGPAV VDTACSS+LVAVH A QAL+SG+C LALAGGV V+ +P Sbjct: 3281 SVASGRIAYTLGLEGPAVTVDTACSSSLVAVHLAAQALRSGECSLALAGGVTVMSTPDAF 3340 Query: 1768 VAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQ 1827 + SR R L+ GRCK F A+ADG +EG G++VL+RLSDA R+G V A++ S+VNQ Sbjct: 3341 IEFSRQRGLAADGRCKPFAAAADGTAWAEGAGMVVLERLSDARRNGHPVLALVRGSAVNQ 3400 Query: 1828 DGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXX 1887 DGAS+GLT PNG +QQR+I LA AGL A+VD +EAHGTGT LGDPIE Q Sbjct: 3401 DGASNGLTAPNGPSQQRVIRQALASAGLDSAEVDAVEAHGTGTRLGDPIEAQALLATYGQ 3460 Query: 1888 XXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALP 1947 PLL+GS+K+NIGH ++A+G AGL K+VL+++HGVLP++LH + P+P + W A Sbjct: 3461 DRPADRPLLLGSLKSNIGHAQAAAGIAGLQKMVLAMRHGVLPRTLHVDAPTPFVDWSAGA 3520 Query: 1948 VRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGT 2007 V ++ E PW +GR RRA +SSFG +GTNAH ++E P + Sbjct: 3521 VSLLTEDTPWPDHGRPRRAAISSFGVSGTNAHTILEHVPDE----YAPDGPDEAGDDAAD 3576 Query: 2008 DDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDS 2067 D + LSARS AL A+R + A PGL A + HT GRS FEYR A+V DS Sbjct: 3577 DGTVLPWLLSARSRAALRAQAQRLLEHTDARPGLRPAAIAHTLATGRSAFEYRGAVVGDS 3636 Query: 2068 VXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTV 2127 + +GV +G V A+LF GQGSQ M EL+ PVFA Sbjct: 3637 REALTGGLKALATAGSASGVTQGTAV-AGKVAFLFAGQGSQRAAMGAELYARYPVFADAF 3695 Query: 2128 RQCAEAVADMLPRPLLDVLF-ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPD 2186 + + +L RPL +V+F A + A L T + QPALFAVE+ L RL + W + PD Sbjct: 3696 DEICAELDPLLDRPLREVVFAAAGSDAAARLDRTEYTQPALFAVEVALFRLVEHWGVVPD 3755 Query: 2187 VVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFA-DAEHVEQVAG 2245 ++LGHS+G+ AAA VAGV + A L+A RGR+ +LPEGG MVA+ A +A+ +A Sbjct: 3756 LLLGHSIGELAAAHVAGVLTAPHAAALVAARGRLMQALPEGGAMVALTASEADATALLAP 3815 Query: 2246 EFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXX 2304 RV+V A NGP + V+SG + + ++ E++ D G + L SHAFHS +D +LD Sbjct: 3816 YDGRVAVAAVNGPASVVVSGDEDAVLDLAEQWRDRGGKARRLTVSHAFHSPHMDAMLDEF 3875 Query: 2305 XXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSV 2364 P +PLV + TG + T + +YW RH R+ V+F + +R +AA G Sbjct: 3876 RRVAESLDYRAPRIPLVSDVTGELATPEQLGSPEYWVRHVREAVRFHDGMRRLAAEGAVT 3935 Query: 2365 LMEIGPQPVLT-------GAAVQVWPEHMAAPRAVAS----LRKGVADRRQIADALASAY 2413 +E+GP LT A + + P AV LRK + R + DALA Y Sbjct: 3936 YLELGPDGSLTAMGRDCLAEADPIDSDDPVDPSAVGPLVPLLRKDRTEIRALTDALAQLY 3995 Query: 2414 VGGHRPDFAAVHRQPRR--PVELPTYPFQRRRFWPKASSIAVDGGTAASG-------ILG 2464 V G D+ V R VELPTY FQR R+W +A+ A GG AA+G +LG Sbjct: 3996 VRGTAVDWPTVLEATGRGGRVELPTYAFQRERYWLEAT--AASGGMAAAGLLSADHPLLG 4053 Query: 2465 SGKDLASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKD 2520 + LA D ++TSRLSV++ PWLADH ++GT + P +A+ A VG ++++ Sbjct: 4054 AAVPLADTDGVLFTSRLSVRTHPWLADHGVFGTALFPATALLELAVRAGDQVGC-GQVEE 4112 Query: 2521 VFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD 2580 + P+++P + S +QLT+ D +H+RP W+ +A G + Sbjct: 4113 LTLETPLVIPAQGSVALQLTVGAPDTTGARPLSVHTRPGDTDDMGWTCHARGLL------ 4166 Query: 2581 PDAAADEQSDPVDEVIERLERMRPQD---LFETFADLELAWGPTWSGSLKSLWLGDGEAV 2637 A ++++P D V +P + L+E FA+ +GP + G L+ +W E Sbjct: 4167 --VPATDETEPADSVTWPPAGAQPVEIDGLYERFAEGGFGYGPAFQG-LREVWRLGDEVY 4223 Query: 2638 GDILVGAELAEQLGSEPMHPVLMD-----LCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQ 2692 + + +E + +HP L+D L GV +G + +LP + Sbjct: 4224 AEASLPSEQQAEAARFGLHPALLDSALHALIFGVL-----------EGTDQGWLPFSWNG 4272 Query: 2693 VTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRG 2752 + L R R + ++ D G+ + IR +LR Sbjct: 4273 IRLHASGARALRIR------LTPAGNNAVSVQAADTAGQPVASIRSL---------VLRP 4317 Query: 2753 LGGDATRL--------LYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRN- 2803 + D R LY L W +P P AD TW + G + G I R+ Sbjct: 4318 VSPDQVRAARTAHHDDLYRLEWPTLPQP--ADAGSDTWAVIGAEAPDWAAHG---ITRSA 4372 Query: 2804 TDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQ 2863 TDL+ L ++Q AR V A G+ + + L+ Sbjct: 4373 TDLKALSREIAQGAARPTAVLAHV-PAAPEGQGRADAVRHVTGRTLTLVQDWLA------ 4425 Query: 2864 GPSVKLPGGLWIVTEHGVACES-GEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSE 2922 S L +VT GV + G+ D AA WG R+ E P L D DG+ Sbjct: 4426 -DSTFADAKLVLVTRDGVPTSADGDAPDLTHAAAWGLARSAQTENPGRFV-LADLDGTRA 4483 Query: 2923 AVDXXXXXXXXPGIQEPEIAVRQGKLLASRL 2953 + D EP++A+R+G+ +RL Sbjct: 4484 SRDALTAAV---ASGEPQLALREGRAHIARL 4511 Score = 1461 bits (3782), Expect = 0.0 Identities = 990/2505 (39%), Positives = 1306/2505 (52%), Gaps = 131/2505 (5%) Query: 15 AIIGYAARFPGAAS-AEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + R+PG A E+ W ++ G +AIS+ P DR WD +DPDP PG TR Sbjct: 37 AIVSMSCRYPGGADDPEQLWDMVSSGTDAISEWPADRGWDTAGLYDPDPDRPGTSYTRHG 96 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ FDA FFGMS RE DPQ R+L+ET+W +E +GI P L + TGVFVG Sbjct: 97 GFLHRAGEFDAAFFGMSPREALATDPQQRLLLETSWETLERAGIDPAVLKGTATGVFVGA 156 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 T+ Y + D+ +++ + GT+ + +GRISY LGL+GPAV VDTACSSSLVA+H Sbjct: 157 MTNGYGDGSRDQ---SDVQGLLHTGTAGSVISGRISYTLGLEGPAVTVDTACSSSLVALH 213 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A +ALR EC LALA G V+ P + FS LAPDGRCK F A ADG EG G Sbjct: 214 LAIRALRSGECSLALACGVTVMPHPDPYVAFSRQRALAPDGRCKAFAAGADGTSWSEGVG 273 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V++++RL DA R G R+ AV+RGSA+NQDGAS GLT PNG +QQRVI AL A L P D Sbjct: 274 VLLLERLSDARRHGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALADARLLPGD 333 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R + PLL+GS K+NIGH Sbjct: 334 VDAVEAHGTGTRLGDPIEAQALLATYGQDRPADRPLLLGSLKSNIGHTSAAAGVGGVIKM 393 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRN-GKPRIAGVSSFGFAGTNA 431 L +E LP+ L+ + P+P + W +E++ E PW + G+PR A VS FG +GTNA Sbjct: 394 VQALRHEVLPRTLHVDAPTPQVDWSAGAVELLTEERPWACDPGRPRRAAVSGFGVSGTNA 453 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQARLA 489 HVILEEAP +P T E E V+P LSAR +AL RA LA Sbjct: 454 HVILEEAPE--SPETPEAPETATPLPVVPWVLSARGEDALTD---------RARQLLALA 502 Query: 490 D--------VSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAP 541 D V+ T T R+ LE RA +V E L ALA A LVRG + A Sbjct: 503 DADALIPGAVARTLATGRSPLEHRAVVVAGDAEGFRTGLTALATGGEAANLVRGLAGPAG 562 Query: 542 KTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDT 601 +T ++F GQG+Q+ GMA EL D+ PVFA + C A+A ++ L DV+ A +L+ Sbjct: 563 RTVFVFPGQGTQWTGMALELLDSSPVFAARMADCERALAPHVDWSLTDVLSSATDLE--- 619 Query: 602 ESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARL 661 QPAL+AV + LA LW+S G EPD V+GHS G+ +AA VAG +EDGA++ Sbjct: 620 -----RVDVVQPALWAVMVSLAALWRSAGVEPDAVLGHSQGEIAAAVVAGALSLEDGAKV 674 Query: 662 IAERGRLFGSLPAGGRMAAVFTAPER-AERLTDEYPSLSVAAYNG-ANTVLSGPAKDLES 719 +A R + ++ G MA+V PE A L LSVAA NG A TVLSG + ++ Sbjct: 675 VALRSQAITAIAGRGGMASVPLPPEELAGHLGPWGDRLSVAAANGPAATVLSGDTEAIDG 734 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQ--RILIDNRTGSAL 777 VA L A+ VR + +A HSA ++ I E + L EP R+ + Sbjct: 735 VVAALRAEDVRARRIPVDYASHSAHVEEIR---ERLLECLADIEPTAGRVPFFSTVDLNW 791 Query: 778 GRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTP 837 S LD YW R+ RQ V F ++ RTL R +E PVLT Sbjct: 792 QDSGTLDAEYWYRNLRQTVRFEEATRTLLAQGFRFFVESSAHPVLTVGISQTAEAEECDA 851 Query: 838 QVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPD-ARKLDLPTYPFEHRQFWFSD 896 + +LR + ++A A+ G PD+ +DLPTYPF+ R++W Sbjct: 852 VAVGTLRRDQGGLDRFLLSLAEAHTGGLAPDWDTLLAGHPGDTVDLPTYPFQRRRYWLER 911 Query: 897 NRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETV-DEQTLRVLNKLAARH 955 A DT E ++L AL V E L V+ A Sbjct: 912 PSADAEDTAATDPADAA--------FWESVGGQDLPALTTTLGVRPEDPLTVVLPALADW 963 Query: 956 NQQRSTHVDPDA-RYEIRWDXXXXXXXXXXXXXD---WILV----GDDTAAVLEFADALT 1007 ++R D+ RY + W W++ +D AL Sbjct: 964 RRRRDERATVDSWRYRVDWRPLADAPAGRTADAPTGTWLVAVTDGTEDDPTREAVVRALR 1023 Query: 1008 AGGHRHQIVALPGSDADEAQLVDTLRAASAGELY-VVHIAAGDGAAAPMRDLLRVQHRTL 1066 G V L + AD A L L AS G + V+ + A D P L + L Sbjct: 1024 EAGAVPVPVVLTEAHADRATLTAHLSEASTGPVSGVLSLVALDERPHPGHPHLPLG---L 1080 Query: 1067 GGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGG 1125 L +A DA + +P+W TR D V P Q +WG GR AALE P WGG Sbjct: 1081 ALTLTLVQALGDAGVTAPLWCATRGAVTTGRDDAVTSPGQHMVWGLGRCAALEHPQRWGG 1140 Query: 1126 LADLSGA-DTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDR- 1183 L DL G D + I + RD EDQ+A+R Y RLVR P+ P R D Sbjct: 1141 LVDLPGTLDERAAARLCGILAGRDDEDQVAVRHSGAYGRRLVR--ARPAG---PARADAW 1195 Query: 1184 ----TYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRV 1239 T LVTGG G +G +A +LA GA H+VL RR V V Sbjct: 1196 QPRGTVLVTGGTGGVGAHLARWLAEGGAEHLVLVGRRGADTPGAADLTAELTALGTRVTV 1255 Query: 1240 ITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAW 1299 DVAD +A L+ + + + ++HAAG PLS D E + KV GA Sbjct: 1256 AACDVADRDRLAELVAGLEQDGSRIGTVIHAAGTGQLVPLSDTDPDEFADILYAKVAGAE 1315 Query: 1300 HLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNF 1359 +L +A+ D R DLD FV SSI+ VWG AY +ANA LD LA R R RG TA SV + Sbjct: 1316 NL-DAVFD-RDDLDSFVLFSSISGVWGSGDHGAYASANAHLDALADRRRARGRTATSVVW 1373 Query: 1360 GPW----AAGMADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLP 1414 G W AGMA +L RG+ ++P AL G+ V+ V V +DW RF P Sbjct: 1374 GIWDPEGGAGMAANLVEEQLRGRGIPFMAPRVALTGLRQVLTDDETVVLVTAVDWDRFAP 1433 Query: 1415 LYQQAGRRAFLSEL-ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR- 1472 ++ A + +L E L +++ P R L+T+ +R Sbjct: 1434 VFTSARPSPLIGDLPEVRRALAEETAPGQDGDDTASSLRDRIADLPPADRDRLLTDLVRA 1493 Query: 1473 NAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAA 1532 +A A + AD I E F +LG DSL AVE+R R+ G +P+T++ D+ A Sbjct: 1494 HAAAVLGHGSADAIAPERAFRELGFDSLTAVEMRNRLNAATGLRLPLTVLFDYASADALA 1553 Query: 1533 DYLLVEVLGLGEQTNVRQA--STVTARTDDPIAVVAVSCRFPG-APDPESFWELLAGGVD 1589 +L E+LG A + V A DDPIA+V +SCR+PG PE W L+A G D Sbjct: 1554 RHLREELLGPDTAAPAGPAVPAHVPADADDPIAIVGMSCRYPGDVRTPEDLWRLVAEGRD 1613 Query: 1590 AIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQ 1648 I +P DR WD+D YD DPD PG TY+ P FFGISPREA+ ++PQQ Sbjct: 1614 VISALPADRGWDLDGLYDTDPDRPGTTYSSEGGFLYDAGQFDPAFFGISPREALAMDPQQ 1673 Query: 1649 RLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALN 1708 RL+LET WE LERAG P+ LRG + GVF G A Y L ++ +++E H I G + + Sbjct: 1674 RLLLETSWEALERAGIDPASLRGGQVGVFAGAAYQGYGGL--SDVPEEVEGHLIAGISTS 1731 Query: 1709 AISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVV 1768 +SGR+A+ LG EGPAV VDTACSS+LVAVH A QAL+SG+C LALAGGV V+ +P++ Sbjct: 1732 ILSGRIAYTLGLEGPAVTVDTACSSSLVAVHLAAQALRSGECSLALAGGVTVMGTPLSFT 1791 Query: 1769 AASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQD 1828 SR R L+ GRCK+F A ADG+ +EG G+L+L+RLSDA R+G V A++ S+VNQD Sbjct: 1792 GFSRQRGLAADGRCKSFGAGADGFGMAEGAGLLLLERLSDARRNGHPVLALVRGSAVNQD 1851 Query: 1829 GASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXX 1888 GAS+GLT P+G AQQR+I + LA AG+ A+VD +EAHGTGT LGDPIE Q Sbjct: 1852 GASNGLTAPSGLAQQRVIRSALAGAGVPSAEVDVVEAHGTGTRLGDPIEAQALLATYGQD 1911 Query: 1889 XXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPV 1948 PLL+GS+K+NIGH+++A+G AG+IK+V +++H LP++LH E P+P++ W V Sbjct: 1912 RPADRPLLLGSLKSNIGHSQAAAGVAGIIKMVQAMRHEELPRTLHAEEPTPNVDWSVGAV 1971 Query: 1949 RVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTD 2008 ++ EP PW NG RRAGVSSFG +GTNAHV++EE + + Sbjct: 1972 ELLTEPRPWTRNGHPRRAGVSSFGLSGTNAHVIIEEPHGE-------------EAGEAPE 2018 Query: 2009 DSPQVLA----LSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALV 2064 + V A LS R+PEAL E A R L+ P L DV T RS FE+RA +V Sbjct: 2019 GNAPVAAVPWLLSGRTPEALREQAARLHARLTDRPELRPHDVGLTLATARSAFEHRAVVV 2078 Query: 2065 -VDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVF 2123 D PA VV G T ++F GQGSQ+ GMA L D+ PVF Sbjct: 2079 GADQATLLTGLAALAAGQDDPA-VVHGTVATPGRTVFVFPGQGSQWAGMAVGLLDSAPVF 2137 Query: 2124 AQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAI 2183 A+ V QC A++ + L DVL + L QP LF+V + LA LW+S + Sbjct: 2138 AERVAQCERALSPYVDWSLTDVL--RGGPDSPPLDRVDVVQPVLFSVMVSLAALWRSHGV 2195 Query: 2184 EPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHV-EQ 2242 EP V+GHS G+ AAA VAG SL+DGAR++A R R+ +L + G M+ V + V E+ Sbjct: 2196 EPSAVIGHSQGEIAAAVVAGALSLEDGARIVALRSRILTTLVDRGAMLFVALPDDRVRER 2255 Query: 2243 VAGEFPRVSVGAYNGPNTV-LSGPGEDLEEIVERFEDEGIRCTWL--ATSHAFHSELLDP 2299 +A R+SV A NGP V +SG E LEE +R ++G+ W+ + A HS +D Sbjct: 2256 MAPWDGRLSVAAVNGPAAVTVSGDPEALEEFGDRLSEDGV-MRWMIPGVTFAGHSPQVDG 2314 Query: 2300 VLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAA 2359 + + TG L T LD +YW R+ R+PV+F ++ + Sbjct: 2315 LRRELLDALAGVTPRRTDVAFYSTVTGGAL-DTTALDTEYWYRNLREPVEFHRALAALVD 2373 Query: 2360 LGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGV-----ADRRQIADALASAYV 2414 G +E+ P PVL VW E VA L G + ALA +V Sbjct: 2374 AGHDTFVEVSPHPVLA-----VWVEKSLEAADVAGLVTGTLHTDDGGPARFLTALAGPHV 2428 Query: 2415 GGHRPDFAAVHR-QPRRPVELPTYPFQRRRFW--PKASSIAVDGG 2456 G D+ AV RPVELPTY FQRRR+W P A+ A +GG Sbjct: 2429 HGVPVDWRAVFAGTDARPVELPTYAFQRRRYWLEPTAALAAGEGG 2473 Score = 635 bits (1637), Expect = e-179 Identities = 405/962 (42%), Positives = 534/962 (55%), Gaps = 58/962 (6%) Query: 1560 DPIAVVAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYT 1617 +PIA+V++SCR+PG A DPE W++++ G DAI E P DR WD YDPDPD PG +YT Sbjct: 34 EPIAIVSMSCRYPGGADDPEQLWDMVSSGTDAISEWPADRGWDTAGLYDPDPDRPGTSYT 93 Query: 1618 RXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVF 1677 R FFG+SPREA+ +PQQRL+LET WE LERAG P+ L+G+ TGVF Sbjct: 94 RHGGFLHRAGEFDAAFFGMSPREALATDPQQRLLLETSWETLERAGIDPAVLKGTATGVF 153 Query: 1678 TGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVA 1737 G N Y + ++ TG A + ISGR+++ LG EGPAV VDTACSS+LVA Sbjct: 154 VGAMTNGYGD--GSRDQSDVQGLLHTGTAGSVISGRISYTLGLEGPAVTVDTACSSSLVA 211 Query: 1738 VHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEG 1797 +H A +AL+SG+C LALA GV V+ P VA SR R L+P GRCK F A ADG SEG Sbjct: 212 LHLAIRALRSGECSLALACGVTVMPHPDPYVAFSRQRALAPDGRCKAFAAGADGTSWSEG 271 Query: 1798 CGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSG 1857 GVL+L+RLSDA R G RV AV+ S+VNQDGAS+GLT PNG +QQR+I A LA A L Sbjct: 272 VGVLLLERLSDARRHGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALADARLLP 331 Query: 1858 ADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLI 1917 DVD +EAHGTGT LGDPIE Q PLL+GS+K+NIGHT +A+G G+I Sbjct: 332 GDVDAVEAHGTGTRLGDPIEAQALLATYGQDRPADRPLLLGSLKSNIGHTSAAAGVGGVI 391 Query: 1918 KVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTN-GRVRRAGVSSFGFTGT 1976 K+V +L+H VLP++LH + P+P + W A V ++ E PW + GR RRA VS FG +GT Sbjct: 392 KMVQALRHEVLPRTLHVDAPTPQVDWSAGAVELLTEERPWACDPGRPRRAAVSGFGVSGT 451 Query: 1977 NAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLA--------LSARSPEALVELA 2028 NAHV++EEAP T ++P+ LSAR +AL + A Sbjct: 452 NAHVILEEAPESPE----------------TPEAPETATPLPVVPWVLSARGEDALTDRA 495 Query: 2029 RRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVV 2088 R+ L+ L V T GRS E+RA +V A +V Sbjct: 496 RQLLA-LADADALIPGAVARTLATGRSPLEHRAVVVAGDAEGFRTGLTALATGGEAANLV 554 Query: 2089 RGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLF- 2147 RG T ++F GQG+Q+ GMA EL D+ PVFA + C A+A + L DVL Sbjct: 555 RGLAGPAGRTVFVFPGQGTQWTGMALELLDSSPVFAARMADCERALAPHVDWSLTDVLSS 614 Query: 2148 ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSL 2207 ATD E D++Q PAL+AV + LA LW+S +EPD VLGHS G+ AAA VAG SL Sbjct: 615 ATDLERVDVVQ------PALWAVMVSLAALWRSAGVEPDAVLGHSQGEIAAAVVAGALSL 668 Query: 2208 DDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF-PRVSVGAYNGP-NTVLSGP 2265 +DGA+++A R + ++ G M +V E + G + R+SV A NGP TVLSG Sbjct: 669 EDGAKVVALRSQAITAIAGRGGMASVPLPPEELAGHLGPWGDRLSVAAANGPAATVLSGD 728 Query: 2266 GEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRT 2325 E ++ +V E +R + +A HS ++ + + +P + Sbjct: 729 TEAIDGVVAALRAEDVRARRIPVDYASHSAHVEEIRERLLECLADIEPTAGRVPFF-STV 787 Query: 2326 GAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEH 2385 LDA+YW R+ RQ V+F E+ RT+ A G +E PVLT Q Sbjct: 788 DLNWQDSGTLDAEYWYRNLRQTVRFEEATRTLLAQGFRFFVESSAHPVLTVGISQTAEAE 847 Query: 2386 MAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF-AAVHRQPRRPVELPTYPFQRRRF 2444 AV +LR+ + +LA A+ GG PD+ + P V+LPTYPFQRRR+ Sbjct: 848 ECDAVAVGTLRRDQGGLDRFLLSLAEAHTGGLAPDWDTLLAGHPGDTVDLPTYPFQRRRY 907 Query: 2445 W---PKA---SSIAVDGGTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVV 2498 W P A + A D AA G+DL + T+ L V+ + L TVV Sbjct: 908 WLERPSADAEDTAATDPADAAFWESVGGQDLPA----LTTTLGVRPEDPL-------TVV 956 Query: 2499 VP 2500 +P Sbjct: 957 LP 958 Score = 179 bits (454), Expect = 7e-42 Identities = 156/466 (33%), Positives = 211/466 (45%), Gaps = 23/466 (4%) Query: 1087 LVTRDGQRVT-DTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITS 1145 LVTRDG + D D + WG R+A E P + LADL G L A + S Sbjct: 4436 LVTRDGVPTSADGDAPDLTHAAAWGLARSAQTENPGRFV-LADLDGTRASRDALTAAVAS 4494 Query: 1146 PRDGEDQIALRGDAVYAPRLVR-RTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYL-A 1203 GE Q+ALR + RL R E ++TP R T L+TGG GAIG +A +L A Sbjct: 4495 ---GEPQLALREGRAHIARLARVPAAEQAETPDWGRPG-TVLITGGTGAIGSVLARHLVA 4550 Query: 1204 SHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPP 1263 HG ++LTSRR P V+ D AD +ARL+ ++ + P Sbjct: 4551 EHGVKRLLLTSRRGPAAEGTADLVVDLAALGAHAEVVACDAADRDALARLLGSLP-DAHP 4609 Query: 1264 LAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIAS 1323 L ++H AG I + + +D KV AW+L E D+ DL FV SSIA Sbjct: 4610 LTAVLHVAGTIADGVVDAMTPGRLDTALRPKVDAAWNLHELTEDM--DLSAFVVFSSIAG 4667 Query: 1324 VWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA------AGMADAESRARLEQ 1377 ++GG GQ Y AAN+FLD LA R G+ A S+ +G WA G+ +A+ R R+ + Sbjct: 4668 IFGGMGQGNYAAANSFLDALAHHRRANGLPAASLAWGLWANKSGMSGGLDEADFR-RIAR 4726 Query: 1378 RGVRTLSPAE--ALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXX 1435 G+ SPAE AL A+ PV + ++D G A L L Sbjct: 4727 GGIVAFSPAEGAALFDSANATGEPVV-LPLRLDTGALAAQTGTGGVPALLRGLVRP-PAR 4784 Query: 1436 XXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRD-EAGFFD 1494 L L P Q+R+ + + +R A V D E G + Sbjct: 4785 RSAAVGEVAPDAADTLRRTLAGQPEQRRERTLLDLVRGHAATVLGFPGPASVDAERGLLE 4844 Query: 1495 LGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVL 1540 LG DSL AVELR R+ G +P TL+ DHP + A L VE++ Sbjct: 4845 LGFDSLTAVELRNRLGAATGLRLPATLLFDHPTSAAIARQLSVELV 4890 Score = 150 bits (380), Expect = 3e-33 Identities = 114/370 (30%), Positives = 161/370 (43%), Gaps = 16/370 (4%) Query: 3294 DRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYA 3353 D + LITGG GA+G H A LA+ GA ++LT RR PD + A Sbjct: 2751 DGTVLITGGTGALGAHVARRLARSGARHLLLTGRRGPDTPGAAELVAELAGLGAETTVAA 2810 Query: 3354 ADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHX 3413 D D +A LLA I E PL + H AG+LDD +L PER L PK A + Sbjct: 2811 CDAADRDALATLLADI-PEDRPLRTVVHAAGLLDDGVLDTLTPERAAGVLRPKMDAALNL 2869 Query: 3414 XXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWG 3473 GQ +YA ANA LD L +RR+ GL AT + +G W Sbjct: 2870 DALTRDLDLTAFVLFSSLAGTLGGTGQGSYAAANAFLDALAEQRRSLGLPATSVAWGLW- 2928 Query: 3474 QGGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSAR 3533 G +++++A + GL P+DP A+ AL + + + + W R A + R Sbjct: 2929 -AGDSAADSARERLVRNGLPPMDPELAVTALEQAMGRAEPRLVLCDFAWDRFAPAYTALR 2987 Query: 3534 PPILDLVLP---------SAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 P LP A + T L +L + +R +T + EV L Sbjct: 2988 PSAALRDLPDVRDVLAATGADRQETEADSLAARLAALSPQERQEELTRLVATEVAAVLGH 3047 Query: 3585 ASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 P F DLG DSL A++LRNRL G ++ T VFD+PT+ L +++ + Sbjct: 3048 PDPAGIDPDRVFKDLGFDSLTAVDLRNRLSEATG--LRLSVTLVFDHPTVTALVDHVRSE 3105 Query: 3643 LPDAEAPETA 3652 L +T+ Sbjct: 3106 LGGTAPAQTS 3115 Score = 135 bits (340), Expect = 1e-28 Identities = 112/370 (30%), Positives = 165/370 (44%), Gaps = 21/370 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG G +G H A +LA+ GA +VL RR D + R+ A DV Sbjct: 1202 LVTGGTGGVGAHLARWLAEGGAEHLVLVGRRGADTPGAADLTAELTALGTRVTVAACDVA 1261 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D ++A+L+A + + + + H AG LS +P+ F L K GA + Sbjct: 1262 DRDRLAELVAGLEQDGSRIGTVIHAAGTGQLVPLSDTDPDEFADILYAKVAGAENLDAVF 1321 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPW---GQ 3474 YA+ANA LD L +RRA+G AT + +G W G Sbjct: 1322 DRDDLDSFVLFSSISGVWGSGDHGAYASANAHLDALADRRRARGRTATSVVWGIWDPEGG 1381 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 GMA++ + +G+ + P AL L +V+ + V +W R A V SARP Sbjct: 1382 AGMAAN-LVEEQLRGRGIPFMAPRVALTGLRQVLTDDETVVLVTAVDWDRFAPVFTSARP 1440 Query: 3535 PILDLVLPS---AAGEAT-----GD---SELLKQLMEIPIPQRAGFVTEFLQREVQNFLR 3583 L LP A E T GD S L ++ ++P R +T+ ++ L Sbjct: 1441 SPLIGDLPEVRRALAEETAPGQDGDDTASSLRDRIADLPPADRDRLLTDLVRAHAAAVLG 1500 Query: 3584 LASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 S A + F +LG DSL A+E+RNRL++ G + + T +FDY + LA +L Sbjct: 1501 HGSADAIAPERAFRELGFDSLTAVEMRNRLNAATGLRLPL--TVLFDYASADALARHLRE 1558 Query: 3642 QL--PDAEAP 3649 +L PD AP Sbjct: 1559 ELLGPDTAAP 1568 Score = 127 bits (319), Expect = 3e-26 Identities = 117/374 (31%), Positives = 164/374 (43%), Gaps = 25/374 (6%) Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 LITGG GAIG A +L A+ G ++LTSRR P +A+ D + + H A V Sbjct: 4532 LITGGTGAIGSVLARHLVAEHGVKRLLLTSRRGP--AAEGTADLVVDLAALGAH--AEVV 4587 Query: 3357 GDEAQVADLLARIRAELP---PLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHX 3413 +A D LAR+ LP PL + H+AG + D ++ A P R T L PK A + Sbjct: 4588 ACDAADRDALARLLGSLPDAHPLTAVLHVAGTIADGVVDAMTPGRLDTALRPKVDAAWNL 4647 Query: 3414 XXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPW- 3472 GQ NYA AN+ LD L RRA GL A + +G W Sbjct: 4648 HELTEDMDLSAFVVFSSIAGIFGGMGQGNYAAANSFLDALAHHRRANGLPAASLAWGLWA 4707 Query: 3473 GQGGMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLG 3530 + GM+ EA I G++ P+ A G L+ + A G Sbjct: 4708 NKSGMSGGLDEADFRRIARGGIVAFSPAEGAALFDSANATGEPVVLPLRLDTGALAAQTG 4767 Query: 3531 SARPPIL--DLVLP-----SAAGEATGDS--ELLKQLMEIPIPQRAGFVTEFLQREVQNF 3581 + P L LV P +A GE D+ L + L P +R + + ++ Sbjct: 4768 TGGVPALLRGLVRPPARRSAAVGEVAPDAADTLRRTLAGQPEQRRERTLLDLVRGHAATV 4827 Query: 3582 LRLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 L P + A L+LG DSL A+ELRNRL + G + AT +FD+PT +A L Sbjct: 4828 LGFPGPASVDAERGLLELGFDSLTAVELRNRLGAATG--LRLPATLLFDHPTSAAIARQL 4885 Query: 3640 -VGQLPDAEAPETA 3652 V +P++ P+ A Sbjct: 4886 SVELVPESAGPDHA 4899 >tr|B4VBW0|B4VBW0_9ACTO Tax_Id=465541 SubName: Full=Polyketide synthase type I; Flags: Fragment;[Streptomyces sp. Mg1] Length = 10873 Score = 1627 bits (4214), Expect = 0.0 Identities = 1134/3020 (37%), Positives = 1547/3020 (51%), Gaps = 205/3020 (6%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + RFPG + E+ W LL G +A++D P DR WD++ +D +P PG TR Sbjct: 1729 AIVAMSCRFPGGVRTPEDLWRLLAQGTDAVADFPADRGWDLDRLYDANPEQPGTSYTREG 1788 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE MDPQ R+L+ET+W A E +GI P L S GVFVG Sbjct: 1789 GFLYDAAEFDAGFFGISPREALAMDPQQRLLLETSWEAFERAGIDPALLKGSQAGVFVGT 1848 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 DYL + + E +E ++ G + + +GR+SY GL+GPA+ VDTACSSSLVA+H Sbjct: 1849 NGQDYLTLVAGEAD--GLEGHVGTGNAASVVSGRLSYVFGLEGPAITVDTACSSSLVALH 1906 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC +ALAGG V+ TP I FS LA DGR K F A ADG GEG G Sbjct: 1907 LAVQALRQGECSMALAGGVTVMSTPDAFIDFSRQRGLAEDGRIKAFAAGADGTGWGEGVG 1966 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DA R+G + AV+RGSAINQDGAS GLT PNG +QQRVI AL AGL A+ Sbjct: 1967 MLLVERLSDAQRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSAAE 2026 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G RA PLL+GS K+NIGH + Sbjct: 2027 VDAVEAHGTGTRLGDPIEAQALLATYGQERAEGLPLLLGSVKSNIGHTQAAAGVAGIIKM 2086 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP+ L+ + P+PH+ W +E++ E W G+PR AGVSSFG +GTNAH Sbjct: 2087 VMAMRHGVLPRTLHVDAPTPHVDWSAGEVELLTEQRDWPETGRPRRAGVSSFGLSGTNAH 2146 Query: 433 VILEEAP-AVGTPATTEPVEDPRRYSV-LPLSARTPEALVRLAGEYRDWLRAHPQARLAD 490 I+E+AP A A T P E ++ ++ + P L A + WL +PQA AD Sbjct: 2147 TIIEQAPDADADEAPTAPAEGTATAALPFAVTGKNPAGLRAQAQQLVSWLAENPQAAPAD 2206 Query: 491 VSHTAGTARAHLEQRAALVVNS--RESAIELLGALADDRPAPGLVRGESHEAPKTAWLFT 548 ++++ R+ E RA +V ++ R++ L ALA A GL+RG + A+LFT Sbjct: 2207 IAYSLAAGRSAFETRAVVVPDAADRDALTAGLRALAAGEHATGLLRGTA-SGGGLAFLFT 2265 Query: 549 GQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHT 608 GQGSQ GM REL+DT PVFA+ + + LE PL DV+F +D + L T Sbjct: 2266 GQGSQRLGMGRELYDTYPVFADALDAVCARMDAHLELPLTDVLFGSDA------AVLDRT 2319 Query: 609 TYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRL 668 Y QPALFAVE+ L RL +SWG +PD V GHS+G+ +AA VAGVF ++D L+A RGRL Sbjct: 2320 EYTQPALFAVEVALFRLAESWGVKPDFVSGHSIGEIAAAHVAGVFSLDDACALVAARGRL 2379 Query: 669 FGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVADG 728 +LP GG M AV + E L E +S+AA NG +V+ +D AVA D Sbjct: 2380 MQALPEGGVMIAVQASEEEVLPLLTE--RVSIAAVNGPRSVVVAGDEDAALAVADAFPDR 2437 Query: 729 VRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYW 788 + L SHAFHS +D +LDDF + L + P ++ N TG AL +W Sbjct: 2438 -KSKRLTVSHAFHSPHMDGMLDDFRRVVEGLSFGAPAIPVVSNLTG-ALVADEMGSAEFW 2495 Query: 789 RRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATA---LAAWPDPATTPQVLASLRP 845 RH R+ V F VR L +E+GP VL+A A L D A P LR Sbjct: 2496 VRHVREAVRFLDGVRVLEGAGVTSFVELGPDGVLSALAQDCLTGDADVAFVPV----LRA 2551 Query: 846 TTADHRQITEAVAAAYAAGHLPDFRAF-RQPDARKLDLPTYPFEHRQFWFSDNRAIDRDT 904 + + AVA A+A G D+ AF AR ++LPTY F+ +++W +T Sbjct: 2552 GRGEAETLVTAVAQAHARGVEVDWSAFFAGTGARSVELPTYAFQRQRYW--------PET 2603 Query: 905 QTASAGSVTPHRTQAV--RLLEDGQIEELAALIDGETVDEQTL--RVLNKLAA-RHNQQR 959 ++ V AV R + + +LA+L+ +V + ++ L+A R Q Sbjct: 2604 VLSNGAVVAAPTVDAVDARFWDAVERGDLASLVAELSVSDDASFGELVPALSAWRRQNQE 2663 Query: 960 STHVDPDARYEIRWDXXXXXXXXXXXXX-DWILV----GDDTAAVLEFADALTA-GGHRH 1013 VD RY + W +W+ V +D A V ALT G Sbjct: 2664 QAQVD-GWRYRVSWKPLAGPAASAGVLGGEWVAVVPSASEDDALVAGVLGALTGRGAEVR 2722 Query: 1014 QIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRT-LGGLRRL 1072 ++V PG+D R A A +L +G G+A+ + LL + + L Sbjct: 2723 RVVVEPGAD----------RVALAEQL------SGFGSASGVVSLLALDEAAGVVATASL 2766 Query: 1073 FRAANDAELRSPIWLVTRDGQRVTDTDTVVPE-QSCLWGFGRAAALELPHIWGGLADLSG 1131 +A DA + +P+W +TR V +D +V Q+ +WG GR AALELP WGGL DL Sbjct: 2767 VQALGDAGVVAPLWCLTRGAVSVGRSDRLVSAVQAQVWGLGRVAALELPERWGGLVDLPE 2826 Query: 1132 ADTEWPRLIARITS--PRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTG 1189 E R +AR+ GEDQ+A+R V+ RLVR +++ P T L+TG Sbjct: 2827 VWDE--RAMARLVGVLAGSGEDQVAVRSSGVFGRRLVRAADGGAESWSP---SGTVLITG 2881 Query: 1190 GLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHD 1249 G GA+G VA +LA G +VLTSRR + DV V+ D +D Sbjct: 2882 GTGALGGRVARWLARAGVERLVLTSRR---GLDAPGAAQLVAELGVDVSVVACDASDRDA 2938 Query: 1250 VARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLR 1309 + L+ AAE L +VH AG + L L + V K A +L E +L Sbjct: 2939 LRALL---AAEAEGLTAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHELTGELG 2995 Query: 1310 TDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG--MA 1367 +L FV SS++ G GQ Y AANA+LD LA + R G+ A S+ +GPWA G A Sbjct: 2996 IELSAFVLFSSMSGSIGAAGQANYAAANAYLDALAEQRRAAGLAATSIAWGPWAEGGMAA 3055 Query: 1368 DAESRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFLS 1426 D AR+ + GV + A+ V A VA ++W R+L + R S Sbjct: 3056 DGALDARMRRDGVPPMDAQPAIRAFRQAVGAADASLTVADVEWERYLSGHTAVRRSELFS 3115 Query: 1427 ELESELXXXXXXXXXXXXXXXXXXLVEQLTK----APVQQRKSLITNYLRNAVAEVTRVD 1482 EL V + AP +Q + L+ +R VA V D Sbjct: 3116 ELTEVRAARAGADARTQPAAHTDGAVTLAGRLAALAPAEQTRELL-GLVRTHVAAVLGHD 3174 Query: 1483 -ADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLG 1541 AD + E F +LG DSL AVELR R+ +PVTL+ D+P + AD+L E++G Sbjct: 3175 GADAVGAERAFKELGFDSLTAVELRNRLGAATELRLPVTLIYDYPTSAALADHLREELVG 3234 Query: 1542 LGEQTNVRQASTVTARTD-DPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR- 1598 + V A D DPIA+VA+SCRFPG PE W+LLA G DA+ + P DR Sbjct: 3235 SIPVSGA--LLPVAAAVDGDPIAIVAMSCRFPGGIASPEDLWQLLAQGTDAVADFPADRG 3292 Query: 1599 WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEG 1658 W++D Y PDPD PG +YTR +FFGISPREA+ ++PQQRL+LET WE Sbjct: 3293 WNLDRLYSPDPDQPGTSYTRHGGFVTGAAEFDADFFGISPREALAMDPQQRLLLETSWEA 3352 Query: 1659 LERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFAL 1718 ERAG PS LRGSR GVF G +Y L++ E D +E H TGNA + +SGRV++ Sbjct: 3353 FERAGIDPSSLRGSRAGVFVGTNGQDYLSLVAREQ-DGLEGHVGTGNAGSVMSGRVSYVF 3411 Query: 1719 GFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSP 1778 G EGPAV VDTACSS+LVA+H A QAL+ G+C LALAGGV V+ +P + SR R L+ Sbjct: 3412 GLEGPAVTVDTACSSSLVALHWAIQALRQGECSLALAGGVTVMSTPENFIDFSRQRGLAE 3471 Query: 1779 VGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPN 1838 GR K F A ADG EG G+L+++RLSDA R+G V AV+ S++NQDGAS+GLT PN Sbjct: 3472 DGRIKAFAAGADGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSAINQDGASNGLTAPN 3531 Query: 1839 GGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMG 1898 G +QQR+I LA AGLS A+VD +EAHGTGT LGDPIE Q PLL+G Sbjct: 3532 GPSQQRVIRQALASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQERSADQPLLLG 3591 Query: 1899 SVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQ 1958 SVK+NIGHT++A+G AG+IK+V+++QHGVLP++LH + P+PH+ W A V ++ E W Sbjct: 3592 SVKSNIGHTQAAAGVAGIIKMVMAMQHGVLPRTLHVDAPTPHVDWSAGEVELLTEQRDWP 3651 Query: 1959 TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV----- 2013 GR RRAG+SSFG +GTNAH ++E+AP D P V Sbjct: 3652 ETGRPRRAGISSFGISGTNAHTIIEQAP-------------DTEQSAPADAQPAVRPARV 3698 Query: 2014 --LALSARSPEAL----VELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDS 2067 LS ++ EA+ L D A G+D D+ ++ R+H + RAALV+ Sbjct: 3699 LPYLLSGKTKEAVRAQAASLTAHLDAAEGADGGVDAEDLAYSLATSRAHLDQRAALVLS- 3757 Query: 2068 VXXXXXXXXXXXXXXTPAGVVRGEHVHRPT--------TAWLFTGQGSQYPGMARELFDT 2119 T A + GE V T TA+LFTGQGSQ GM REL+D Sbjct: 3758 ------VADGQDLRETLARLAAGESVAGITTGTAGDARTAFLFTGQGSQRLGMGRELYDA 3811 Query: 2120 QPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQ 2179 PVFA + + +L RPL DVLF +D A +L T + QPALFAVE+ L+RL + Sbjct: 3812 HPVFADALDAVCAQLDAVLDRPLKDVLFGSD---ASVLDETRYTQPALFAVEVALSRLVE 3868 Query: 2180 SWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEH 2239 SW + PD + GHS+G+ AAA VAGVFSL+D L+A RGR+ +LP GG M+AV A + Sbjct: 3869 SWGVRPDFLSGHSIGEIAAAHVAGVFSLEDACALVAARGRLMQALPTGGVMIAVQASEDE 3928 Query: 2240 VEQVAGEFPRVSVGAYNGPNTVLSGPGEDLE-EIVERFEDEGIRCTWLATSHAFHSELLD 2298 V + + RVS+ A NGP +V+ ED + E F D + L SHAFHS +D Sbjct: 3929 VLPLLND--RVSIAAVNGPRSVVVAGDEDAALAVAEAFPDR--KSKRLTVSHAFHSPHMD 3984 Query: 2299 PVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVA 2358 +L+ P +P+V N TGA++T + A++W RH R+ V+F + VR + Sbjct: 3985 GMLEDFRQVVAGLSFEAPRIPVVSNLTGALVTDEM-ASAEFWVRHVREAVRFLDGVRALE 4043 Query: 2359 ALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHR 2418 A G + +E+GP VL+ A + A A LR G + + ALA A+ G Sbjct: 4044 AAGVTAYVELGPDGVLSALAQDCLTDTTHTTFAPA-LRAGRPEAETLVTALARAHAHGVE 4102 Query: 2419 PDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSI------AVDGGTAASGILGSGKDLAS 2471 D++A R V+LPTY FQR+RFWP A+ A+ G A +L + LA Sbjct: 4103 VDWSAYFAGSGARRVDLPTYAFQRQRFWPSAALFAAGDPEAIGFGDAGHPLLSAAVALAD 4162 Query: 2472 GD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPI 2527 + + RLSV++ PWL DH I G+ ++PG + +A+ A VG ++++ P+ Sbjct: 4163 SEGVLLAGRLSVETHPWLVDHTILGSALLPGTAFVELAIRAGDEVGCDV-VEELTLEAPL 4221 Query: 2528 ILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGA----DWSLNAEGTVDTAGSDPDA 2583 +LPE+ ++QL + F ++SR R A W+ + G + AG+ P+A Sbjct: 4222 VLPERGGVQLQLVVEAPTEPGRRPFSVYSR---RRDALTEESWTRHGSGVL-AAGARPEA 4277 Query: 2584 A---ADEQSDPVDEVIERLERMRPQDLFETFADLE---LAWGPTWSGSLKSLWLGDGEAV 2637 A AD P + P D+ + DL +++GP + G LK+ W DGE Sbjct: 4278 ALAFADLAEWPPAGAV-------PVDIDGLYTDLAQAGVSYGPLFQG-LKAAWRRDGELF 4329 Query: 2638 GDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAE 2697 ++++ + +HP L+D EQ LP + V+L Sbjct: 4330 TEVVLPEDGHGDAARFGLHPALLD----AGLHAIGHGDPAEQAATGALLPFSWAGVSLYA 4385 Query: 2698 KMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDA 2757 R SA D T L D GR + + T++ A + + G Sbjct: 4386 AGASSLRMRLT-PNSAGDPHT--LALLVTDETGRPVAAVESLTLRPASADQ-VSAAGAGH 4441 Query: 2758 TRLLYTLGWHEVPPPPSADDAVG-TWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQA 2816 L+ + W P P A G W + G DE+ + D LG L+ Sbjct: 4442 LESLFRVEW---APAPVATAPTGLRWGVLGRDEIGLAGSTGAQVTEYADAAALGAALAAG 4498 Query: 2817 H-ARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWI 2875 A A F VV PG + L+ A V L G Sbjct: 4499 EPAFDAVF--VVPSAPVPGADVVGSVHTAVNDALAVVQEWLADERFAATRLVWLTSG--- 4553 Query: 2876 VTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXP 2934 VA SGE V D +A+ G R+ +E P L + S AV Sbjct: 4554 ----AVAVGSGEGVRDLAGSAVRGLLRSAQSENPGQLLMLDVDEASLGAVPAAL------ 4603 Query: 2935 GIQEPEIAVRQGKLLASRLL 2954 E E+A+R G + RL+ Sbjct: 4604 AAGEFELAIRSGVVCVPRLV 4623 Score = 1619 bits (4193), Expect = 0.0 Identities = 1077/2852 (37%), Positives = 1487/2852 (52%), Gaps = 155/2852 (5%) Query: 16 IIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAG 73 I+G R+PG S EE W L+ G + ++ P DR W++E + PDP G TR G Sbjct: 5039 IVGMGCRYPGGVRSPEELWQLVATGGDGVTTFPSDRGWNVEALYHPDPDHAGTSYTREGG 5098 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 F+ DV FD FFG+S RE MDPQ R+L+ET+W A E +GI P +L S TGVF G+ Sbjct: 5099 FLHDVADFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGVM 5158 Query: 134 THDYL-------GMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSS 186 HDY+ G S + +E Y+ G + + A+GRI+Y GL+GPAV VDTACSS Sbjct: 5159 YHDYVTGFGLGDGAGSGDALPEGVEGYLGTGNAGSIASGRIAYTFGLEGPAVTVDTACSS 5218 Query: 187 SLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYV 246 SLVA+H A QALR ECD+ALAGG V+ TP T + FS L+ DGRCK+F AAADG Sbjct: 5219 SLVALHWAIQALRGGECDMALAGGVAVMATPETFVDFSRQRGLSADGRCKSFAAAADGTG 5278 Query: 247 RGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRA 306 EG G+++V+R DA+R+G I AV+RGSA+NQDGAS GLT PNG +QQRVI +AL A Sbjct: 5279 WAEGAGMLLVERQSDALRNGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIREALASA 5338 Query: 307 GLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXX 366 GL DV +EAHGTGT LGDPIEAQA G R PLL+GS K+NIGH + Sbjct: 5339 GLSAVDVDAVEAHGTGTRLGDPIEAQALLATYGQDRPEGRPLLLGSIKSNIGHTQAAAGV 5398 Query: 367 XXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGF 426 + + LP+ L+ + PS + WE + ++ + + W + G+PR AG+SSFG Sbjct: 5399 AGIIKMVMAMRHGVLPQTLHVDAPSTQVEWEAGDVSLLTQAMDWPQTGRPRRAGISSFGI 5458 Query: 427 AGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLP-----LSARTPEALVRLAGEYRDWLR 481 +GTNAH I+E+ P + +P ++LP LSA+ +AL A + + Sbjct: 5459 SGTNAHTIIEQPPVLER-------AEPEAAALLPAVPWVLSAKGEDALRAQARQLHSHVA 5511 Query: 482 AHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAP 541 + P AR DV+ + RA E RAA+V RE + L ALA+ R LV G S A Sbjct: 5512 STPGARPVDVAWSLAANRASFEDRAAVVAADREGLLAGLAALAEGRSTATLVEG-SPVAG 5570 Query: 542 KTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDT 601 K A+LFTGQGSQ GM REL++ PVFA + E + LE PL +V+F G+ Sbjct: 5571 KLAFLFTGQGSQRLGMGRELYEAYPVFAAALDAVCERLD--LELPLKEVLF------GND 5622 Query: 602 ESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARL 661 L T + QPALFAVE+ L RL +SWG D + GHSVG+ +AA VAGVF ++D L Sbjct: 5623 REVLDRTEFTQPALFAVEVALFRLLESWGVRADFLSGHSVGEIAAAHVAGVFSLDDACAL 5682 Query: 662 IAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAV 721 +A RGRL +LP GG M AV + + L E +S+AA NG +V+ +D AV Sbjct: 5683 VAARGRLMQALPEGGVMIAVQASEDEVLPLLTE--RVSIAAINGPRSVVVAGDEDAALAV 5740 Query: 722 ATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRST 781 A D + L SHAFHS +D +LDDF + L ++ P+ L+ N TG AL Sbjct: 5741 AAAFPDR-KSKRLTVSHAFHSPHMDGMLDDFRRVVEGLSFQAPRIPLVSNLTG-ALIADE 5798 Query: 782 RLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATA---LAAWPDPATTPQ 838 +W RH R+ V F VR L +E+GP VL+A A LA D A P Sbjct: 5799 MGSAEFWVRHVREAVRFLDGVRALEGAGVTSFVELGPDGVLSALAQDCLAGDADVAFVP- 5857 Query: 839 VLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDN 897 LR + + AVA A+ G D+ A F AR ++LPTY F+ +++W Sbjct: 5858 ---VLRAGRGEAETLVTAVAQAHVRGVEVDWSAFFAGTGARSVELPTYAFQRQRYWLQLT 5914 Query: 898 RAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQT--LRVLNKLAARH 955 A+ ++ + V AV + E++A+L+ +D++ VL L+A Sbjct: 5915 GAV----RSGAGYDVDSRFWDAV------EREDVASLVGTLAMDDENGWSAVLPALSAWR 5964 Query: 956 NQQRSTHVDPDARYEIRW-DXXXXXXXXXXXXXDWILV-----GDDTAAVLEFADALTAG 1009 R+ RY + W W++V DDT V A G Sbjct: 5965 RGLRTQSEVDRWRYRVSWKPLTDAAAAGVRLSGSWLVVVPAEGVDDTPVVAALAG---RG 6021 Query: 1010 GHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGL 1069 ++V +DAD A L + A + VV + A D AA + VQ Sbjct: 6022 AEVRRVVV--EADADRAGLFSDVGAVAG----VVSLLALDEAAGVVATASLVQ------- 6068 Query: 1070 RRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPE-QSCLWGFGRAAALELPHIWGGLAD 1128 A DA + +P+W +TR V +D +V Q+ WG GR AALELP WGGL D Sbjct: 6069 -----ALGDAGVEAPLWCLTRGAVSVGRSDRLVSAVQAQTWGLGRVAALELPERWGGLVD 6123 Query: 1129 LSGADTEWPRLIARITS--PRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYL 1186 L E R +AR+ GEDQ+A+R V+ RLVR T +++ P T L Sbjct: 6124 LPEVWDE--RAMARLVGVLAGSGEDQVAVRSSGVFGRRLVRATAGNAESWTP---SGTVL 6178 Query: 1187 VTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVAD 1246 VTGG GA+G VA +LA G +VLTSRR DV V+ D AD Sbjct: 6179 VTGGTGALGGRVARWLAGAGVERLVLTSRRGLDAPGAAELVAELSGLGVDVSVVACDAAD 6238 Query: 1247 AHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALT 1306 D R++ + AE L +VH AG + L L + V K A +L E Sbjct: 6239 -RDALRVL--LEAEAEGLTAVVHTAGVLDDGVLDALTPERFEGVLRAKATSALNLHELTG 6295 Query: 1307 DLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG- 1365 +L +L FV SS++ + G GQ Y AANA+LD LA + R G+ A S+ +GPWA G Sbjct: 6296 ELGIELSAFVLFSSMSGMTGAAGQGNYAAANAYLDALAEQRRAAGLAATSLAWGPWAEGG 6355 Query: 1366 -MADAESRARLEQRGVRTLSPAEALAGMAD--VVAGPVQGVVAKIDWSRFLPLYQQAGRR 1422 AD AR+ + G+ ++P A+A + V + +VA +DW RF P + A Sbjct: 6356 MAADEAMDARMRREGLPPMAPDTAMAVLRQSVVPSSDAALLVADVDWDRFGPAFTVARPS 6415 Query: 1423 AFLSELESELXXXXXXXXXXXXXXXXXXLVEQLT-KAPVQQRKSLITNYLRNAVAEVTRV 1481 +EL V++ A V+ + L+ + A + Sbjct: 6416 TLFAELSE------TRPAAEGAATGTGTSVDRFAGLAAVELERELLGLVRTHVAAVLGHE 6469 Query: 1482 DADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLG 1541 A+ + E F +LG DSL AVELR R+ G +P TL+ D+P S +L E+LG Sbjct: 6470 GAETVGAERAFKELGFDSLTAVELRNRLGAATGVSLPATLIFDYPTASAITAFLRDELLG 6529 Query: 1542 LGEQTNVRQASTVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-W 1599 + ++ VT DDPIA+VA+SCRFP G PE W+LLA G DAI E P DR W Sbjct: 6530 TQARIAGPVSTAVTPVDDDPIAIVAMSCRFPGGVRTPEDLWQLLAAGGDAIGEFPVDRGW 6589 Query: 1600 DIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGL 1659 D+D Y+PDPD G Y R +FFGISPREA+ ++PQQRL+LET WE Sbjct: 6590 DLDRLYNPDPDQQGTFYAREGGFLYDAADFDADFFGISPREALAMDPQQRLLLETTWETF 6649 Query: 1660 ERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALG 1719 ERAG P+ +RGS+ GVF G +Y + D IE TGNA + +SGR+++A G Sbjct: 6650 ERAGIDPAAVRGSQAGVFIGTNGQDYDATFHSVP-DGIEGFLGTGNAASVVSGRLSYAFG 6708 Query: 1720 FEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPV 1779 EGPAV VDTACS++LVA+H A QAL+ G+CD+ALAGGV V+ SP + SR R L+ Sbjct: 6709 LEGPAVTVDTACSASLVALHWAIQALRGGECDMALAGGVTVMSSPGAYIDFSRQRGLAED 6768 Query: 1780 GRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNG 1839 GR K F A ADG EG G+L+++RLSDA R+G V AV+ S++NQDGAS+GLT PNG Sbjct: 6769 GRIKAFSADADGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSAINQDGASNGLTAPNG 6828 Query: 1840 GAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGS 1899 +QQR+I A LA AGLS A+VD +EAHGTGT LGDPIE Q PLL+GS Sbjct: 6829 PSQQRVIRAALASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQERAEEQPLLLGS 6888 Query: 1900 VKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT 1959 +K+NIGHT++A+G AG+IK+VL++QHGVLPQ+LH P+PH+ W A V ++ E W Sbjct: 6889 IKSNIGHTQAAAGVAGVIKMVLAMQHGVLPQTLHVNEPTPHVDWSAGEVALLTEQRDWPE 6948 Query: 1960 NGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSAR 2019 GR RRAG+SSFGF+GTNAH ++E+AP L P V LSA+ Sbjct: 6949 TGRPRRAGISSFGFSGTNAHTIIEQAPDVLDVEPSVQPQERPGGVL-----PWV--LSAK 7001 Query: 2020 SPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXX 2079 + AL A R +++ L+ ADV ++ RS E RA +V Sbjct: 7002 NEAALRVQAERLLAAVTSDELLEPADVAYSLATSRSALERRAVVVAGERDEFLAALRALA 7061 Query: 2080 XXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLP 2139 AGV G TA+LFTGQGSQ GM REL+D PVFA + + L Sbjct: 7062 AGEQTAGVAHGT-AAVGGTAFLFTGQGSQRLGMGRELYDAHPVFADALDAICARMDGHLE 7120 Query: 2140 RPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAA 2199 PL +VLF +D A +L T + QPALFAVE+ L RL +SW I PD + GHS+G+ AAA Sbjct: 7121 LPLKEVLFGSD---AAVLDRTEYTQPALFAVEVALFRLVESWGIRPDFLSGHSIGEIAAA 7177 Query: 2200 CVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPN 2259 VAGV SLDD L+A RGR+ +LP GG M+AV A E V + + RVS+ A NGP Sbjct: 7178 HVAGVLSLDDACALVAARGRLMQALPSGGVMIAVEASEEEVLPLLTD--RVSIAAVNGPR 7235 Query: 2260 TVLSGPGEDLE-EIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTL 2318 +V+ ED + E F D + L SHAFHS +D +L+ P + Sbjct: 7236 SVVIAGDEDAAVALAESFADR--KSKRLTVSHAFHSPHMDGMLEDFRQVVAGLSFEAPRI 7293 Query: 2319 PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAA 2378 P+V N TGA++T + A++W RH R+ V+F + +R + A G + +E+GP VL+ A Sbjct: 7294 PVVSNLTGALVTDEMG-SAEFWVRHVREAVRFLDGIRVLEAAGVTAYVELGPDGVLSALA 7352 Query: 2379 VQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTY 2437 + + + +LRKG + + L A+ G D++A R V+LPTY Sbjct: 7353 QGCLADENSNALFMPALRKGRPEAETLVTTLGQAHAHGVEVDWSAYFAGSGARRVDLPTY 7412 Query: 2438 PFQRRRFWPKASSI------AVDGGTAASGILGSGKDLASGD-TIYTSRLSVKSQPWLAD 2490 FQR+RFWP A+ A+ G A +L + LA + + RL++ + PWLAD Sbjct: 7413 AFQRQRFWPSAALFAAGDPEAIGFGDAGHPLLSAAVALADSEGVLLAGRLALDTHPWLAD 7472 Query: 2491 HVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGG 2547 H+I G+ ++PG + +A+ A VG ++++ P++LPE+ ++QL + Sbjct: 7473 HMILGSALLPGTAFVELAIRAGDEVGCDV-VEELTLEAPLVLPERGGVQLQLVVEAPMAP 7531 Query: 2548 SVLSFQIHSRPYGERGAD-WSLNAEGTVDTAGSDPDAAADEQSDPVDEVIE-RLERMRPQ 2605 F ++SR + W+ + G + AG+ P+A S E+ E P Sbjct: 7532 GRRPFSVYSRRQDALAEEPWTRHGSGVL-AAGAQPEA-----SQEFGELAEWPPAGAAPV 7585 Query: 2606 DLFETFADLE---LAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDL 2662 D+ +A+L +A+GP + G LK+ W DGE ++++ + +HP L+D Sbjct: 7586 DIDGLYAELAGDGMAYGPLFQG-LKAAWRRDGELFTEVVLPEDGRGDAARFGLHPALLD- 7643 Query: 2663 CTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFE 2722 EQG + LP + V+L R + + + Sbjct: 7644 ---AGLHAIGHGDPAEQGASGALLPFSWAGVSLYAVGAPALRMRLTPNSA---GDPHALA 7697 Query: 2723 LEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGTW 2782 L D GR + + ++ A + + G L+ + W P P + A W Sbjct: 7698 LLVADETGRPVAAVESLMLRPASSDQ-VSAAGAGHLESLFRVEWLPAPVAPVSAPAGLRW 7756 Query: 2783 LIAGFDELAAKVPGCVPIDRNTDLQVLGEVLS 2814 + G DE+ + D+ LG L+ Sbjct: 7757 GVLGRDEIGLGSSTGAEVTEYADVTALGAALA 7788 Score = 1583 bits (4099), Expect = 0.0 Identities = 1007/2493 (40%), Positives = 1349/2493 (54%), Gaps = 112/2493 (4%) Query: 2 VSAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDP 59 +S++ PI AI+G RFPG S E W L+ +G +AIS+ P R W+++ +DP Sbjct: 175 ISSDEPI------AIVGIGCRFPGDVHSPEALWELVANGTDAISEFPTGRGWNLDSLYDP 228 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 DP G R GF+ D FDA FFG+S RE MDPQ R+L+ET+W A + +GI P+ Sbjct: 229 DPDRAGTTYAREGGFLHDADEFDAAFFGISPREALAMDPQQRLLLETSWEAFDRAGIDPS 288 Query: 120 SLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVA 179 L GVFVG T +Y D E Y+ G + + A+GRI+Y G +GP V Sbjct: 289 GLRGGQIGVFVGAETQEYGPRLEDAAD--GFEGYLVTGNAASVASGRIAYTFGFEGPTVT 346 Query: 180 VDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFD 239 VDTACSSSL A+H A QALR EC LALAGG ++ +P + ++FS LAPDGRCK F Sbjct: 347 VDTACSSSLAALHLAVQALRSGECSLALAGGVAIMASPGSFVSFSRQRGLAPDGRCKPFA 406 Query: 240 AAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI 299 A ADG GEG G+++V+RL DA G I AV+RG+AINQDGAS GLT P+G AQQRVI Sbjct: 407 AGADGTAWGEGAGMLLVERLSDARAAGHHILAVVRGTAINQDGASNGLTAPSGPAQQRVI 466 Query: 300 ADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGH 359 AL AGL ADV +EAHGTGT+LGDPIEAQA G R + PL +GS K+NIGH Sbjct: 467 RQALANAGLTSADVDAVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSLKSNIGH 526 Query: 360 LEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIA 419 + + + LP+ L+ + P+PH+ WE + ++ + V W PR A Sbjct: 527 TQAAAGVAGVIKMVMAMRHGVLPQTLHVDAPTPHVDWEAGAVSLLTQPVAWPTADAPRRA 586 Query: 420 GVSSFGFAGTNAHVILEE-------------APAVGTPATTEPVEDPRRYSVLP--LSAR 464 GVSSFG +GTNAH I+EE PA PAT EP + +LP LSA+ Sbjct: 587 GVSSFGMSGTNAHAIIEEPPTEDAAQHTEDQPPAQEAPATDEPEAAADQLPLLPWALSAK 646 Query: 465 TPEALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALA 524 TPEAL A DWL HP A AD+ H+ T R+ E RA ++ + R + L ALA Sbjct: 647 TPEALRATARRLGDWLDTHPDATPADIGHSLATTRSRFEHRAVVLGDDRTALQRGLRALA 706 Query: 525 DDRPAPGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILE 584 + P ++ GE A + A LFTGQGSQ M REL++T PVFA+ + + + + LE Sbjct: 707 EAADTPAVIHGEP-GAGRPAVLFTGQGSQRLAMGRELYETYPVFADALDDASWYLDEQLE 765 Query: 585 KPLLDVIFDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQY 644 PLLDV+F ADE D + L T Y QPALFAVE+ L RL +SWG P V GHSVG+ Sbjct: 766 HPLLDVLF-ADE-DTPEAALLHQTAYTQPALFAVEVALYRLVESWGLRPAFVAGHSVGEI 823 Query: 645 SAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAY 703 +AA VAGVF +ED L+A RGRL +LP GG M AV + + LTD +S+AA Sbjct: 824 AAAHVAGVFTLEDACALVAARGRLMQALPTGGVMIAVQASEDEVLPLLTDR---VSIAAI 880 Query: 704 NGANTVLSGPAKDLESAVA-TLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYR 762 NG +V+ +D AVA A G + L SHAFHS +D +LD F AQ L+Y Sbjct: 881 NGPQSVVVAGDEDAALAVAEAFEAQGRKTKRLTVSHAFHSPHMDAMLDAFRRVAQVLDYG 940 Query: 763 EPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVL 822 P ++ TG+ + +W RH R+ V F VRTL LE+GP PVL Sbjct: 941 TPTLPVVSLLTGTTATAAELASPEHWVRHVREAVRFLDGVRTLRARGADSFLELGPDPVL 1000 Query: 823 TATA---LAAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDAR 878 TA A L P T P A+LR + + +AVA + G D+ A F AR Sbjct: 1001 TAMAQDCLVTDPQDTTNPVFAAALRSGRPEPTTLLDAVARMFVRGAETDWAAYFAGTGAR 1060 Query: 879 KLDLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGE 938 ++LPTY F+ +++W + R + T+ A P +E + LAA ++ + Sbjct: 1061 SVELPTYAFQRQRYWM-NARTPATEPATSPAHRTDPADNAFWDAVEHQDVAALAAALELD 1119 Query: 939 TVDEQTL-RVLNKLAARHNQQRSTHVDPDARYEIRW-DXXXXXXXXXXXXXDWILV---- 992 EQ L V+ L+A + R+ RY W W++V Sbjct: 1120 ADGEQPLSEVVPALSAWRRRVRTQSEVDGWRYRASWKPLTDAAAGGVRLSGSWLVVVPSE 1179 Query: 993 -GDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDGA 1051 DDTA V A G ++V G D A L + + + VV + A D A Sbjct: 1180 GVDDTAVVAALAG---RGAEVRRVVVEAG--VDRAGLFSDVGSVAG----VVSLLALDEA 1230 Query: 1052 AAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPE-QSCLWG 1110 A + VQ A A + +P+W +TR V +D +V Q+ WG Sbjct: 1231 AGVVSTASLVQ------------ALGAAGVVAPLWCLTRGAVSVGRSDRLVSAVQAQTWG 1278 Query: 1111 FGRAAALELPHIWGGLADLSGADTEWPRLIARITS--PRDGEDQIALRGDAVYAPRLVRR 1168 GR AALELP WGGL DL E R +AR+ GEDQ+A+R V+ RLVR Sbjct: 1279 LGRVAALELPERWGGLVDLPEVWDE--RAMARLVGVLAGSGEDQVAVRSSGVFGRRLVRA 1336 Query: 1169 TGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXX 1228 +++ P T L+TGG GA+G VA +LA G +VLTSRR Sbjct: 1337 ADGGAESWSP---SGTVLITGGTGALGGRVARWLAGAGVERLVLTSRR---GLDAPGAAE 1390 Query: 1229 XXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVD 1288 + D+ V+ D AD D R + +AAE L +VH AG + L L + Sbjct: 1391 LVAELGVDLSVVACDAAD-RDALRAL--LAAEAEGLTAVVHTAGVLDDGVLDALTPERFE 1447 Query: 1289 RVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLR 1348 V K A +L E +L +L FV SS++ G GQ Y AANA+LD LA + R Sbjct: 1448 SVLRAKATSALNLHELTGELGIELSAFVLFSSMSGSIGAAGQANYAAANAYLDALAEQRR 1507 Query: 1349 ERGVTAVSVNFGPWAAG--MADAESRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVA 1405 G+ A S+ +GPWA G AD AR+ + GV ++P A+A +A V AG VA Sbjct: 1508 AAGLAATSIAWGPWAEGGMAADEAMDARMRREGVPPMAPDSAIAALAQAVGAGEAALTVA 1567 Query: 1406 KIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLV----EQLTKAPVQ 1461 I W RF + +++ + + +L + P Sbjct: 1568 DIAWDRFSSVVAAVRPNPSVADFATAASQGAASVTGQGTVVTGADVAGAAFAKLAELPRA 1627 Query: 1462 QRKSLITNYLRNAVAEVTRVD-ADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVT 1520 ++ + +R VA V D AD + E F +LG DSL AV+LR R+ +P T Sbjct: 1628 EQDRELLGLVRTHVAAVLGHDGADAVGAERAFKELGFDSLTAVDLRNRLGAATALRLPAT 1687 Query: 1521 LVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFP-GAPDPES 1579 LV D+P S A+YL E++G + + Q A DDPIA+VA+SCRFP G PE Sbjct: 1688 LVYDYPTSSALAEYLRGELMGNAPKADSPQ-HVAAATDDDPIAIVAMSCRFPGGVRTPED 1746 Query: 1580 FWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISP 1638 W LLA G DA+ + P DR WD+D YD +P+ PG +YTR FFGISP Sbjct: 1747 LWRLLAQGTDAVADFPADRGWDLDRLYDANPEQPGTSYTREGGFLYDAAEFDAGFFGISP 1806 Query: 1639 REAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIE 1698 REA+ ++PQQRL+LET WE ERAG P+ L+GS+ GVF G +Y L++ E+ D +E Sbjct: 1807 REALAMDPQQRLLLETSWEAFERAGIDPALLKGSQAGVFVGTNGQDYLTLVAGEA-DGLE 1865 Query: 1699 PHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGV 1758 H TGNA + +SGR+++ G EGPA+ VDTACSS+LVA+H A QAL+ G+C +ALAGGV Sbjct: 1866 GHVGTGNAASVVSGRLSYVFGLEGPAITVDTACSSSLVALHLAVQALRQGECSMALAGGV 1925 Query: 1759 NVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCA 1818 V+ +P + SR R L+ GR K F A ADG EG G+L+++RLSDA R+G V A Sbjct: 1926 TVMSTPDAFIDFSRQRGLAEDGRIKAFAAGADGTGWGEGVGMLLVERLSDAQRNGHPVLA 1985 Query: 1819 VIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEV 1878 V+ S++NQDGAS+GLT PNG +QQR+I LA AGLS A+VD +EAHGTGT LGDPIE Sbjct: 1986 VVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSAAEVDAVEAHGTGTRLGDPIEA 2045 Query: 1879 QXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPS 1938 Q PLL+GSVK+NIGHT++A+G AG+IK+V++++HGVLP++LH + P+ Sbjct: 2046 QALLATYGQERAEGLPLLLGSVKSNIGHTQAAAGVAGIIKMVMAMRHGVLPRTLHVDAPT 2105 Query: 1939 PHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXX 1998 PH+ W A V ++ E W GR RRAGVSSFG +GTNAH ++E+AP Sbjct: 2106 PHVDWSAGEVELLTEQRDWPETGRPRRAGVSSFGLSGTNAHTIIEQAP------DADADE 2159 Query: 1999 XXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFE 2058 GT + A++ ++P L A++ WL+ P AD+ ++ GRS FE Sbjct: 2160 APTAPAEGTATAALPFAVTGKNPAGLRAQAQQLVSWLAENPQAAPADIAYSLAAGRSAFE 2219 Query: 2059 YRAALVVDSV--XXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMAREL 2116 RA +V D+ G++RG A+LFTGQGSQ GM REL Sbjct: 2220 TRAVVVPDAADRDALTAGLRALAAGEHATGLLRGT-ASGGGLAFLFTGQGSQRLGMGREL 2278 Query: 2117 FDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLAR 2176 +DT PVFA + + L PL DVLF +D A +L T + QPALFAVE+ L R Sbjct: 2279 YDTYPVFADALDAVCARMDAHLELPLTDVLFGSD---AAVLDRTEYTQPALFAVEVALFR 2335 Query: 2177 LWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFAD 2236 L +SW ++PD V GHS+G+ AAA VAGVFSLDD L+A RGR+ +LPEGG M+AV A Sbjct: 2336 LAESWGVKPDFVSGHSIGEIAAAHVAGVFSLDDACALVAARGRLMQALPEGGVMIAVQAS 2395 Query: 2237 AEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLE-EIVERFEDEGIRCTWLATSHAFHSE 2295 E V + E RVS+ A NGP +V+ ED + + F D + L SHAFHS Sbjct: 2396 EEEVLPLLTE--RVSIAAVNGPRSVVVAGDEDAALAVADAFPDR--KSKRLTVSHAFHSP 2451 Query: 2296 LLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVR 2355 +D +LD P +P+V N TGA++ + A++W RH R+ V+F + VR Sbjct: 2452 HMDGMLDDFRRVVEGLSFGAPAIPVVSNLTGALVADEMG-SAEFWVRHVREAVRFLDGVR 2510 Query: 2356 TVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVG 2415 + G + +E+GP VL+ A Q A V LR G + + A+A A+ Sbjct: 2511 VLEGAGVTSFVELGPDGVLS-ALAQDCLTGDADVAFVPVLRAGRGEAETLVTAVAQAHAR 2569 Query: 2416 GHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPK 2447 G D++A R VELPTY FQR+R+WP+ Sbjct: 2570 GVEVDWSAFFAGTGARSVELPTYAFQRQRYWPE 2602 Score = 1575 bits (4079), Expect = 0.0 Identities = 1009/2487 (40%), Positives = 1344/2487 (54%), Gaps = 134/2487 (5%) Query: 16 IIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAG 73 I+G R+PG + EE W L+ G + ++ P DR W++E + PDP G TR G Sbjct: 8333 IVGMGCRYPGGVRTPEELWQLVASGGDGVTAFPTDRGWNVEALYHPDPDHVGTSYTREGG 8392 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 F+ DV FDA FFG+S RE MDPQ R+L+ET+W A E +GI P +L S TGVF G+ Sbjct: 8393 FLHDVAEFDAAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGVM 8452 Query: 134 THDYL-GMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 HDY G + E +E Y+ G S + A+GR+SY GL+GPAV VDTACSSSLVA+H Sbjct: 8453 YHDYATGYGNGEELPEGVEGYLGTGNSGSIASGRVSYAFGLEGPAVTVDTACSSSLVALH 8512 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR ECD+ALAGG V+ TP T + FS L+ DGRCK+F AAADG EG G Sbjct: 8513 WAIQALRGGECDMALAGGVAVMATPETFVDFSRQRGLSADGRCKSFAAAADGTGWAEGAG 8572 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+R DA+R+G I AV+RGSAINQDGAS GLT PNG +QQRVI AL AGL +D Sbjct: 8573 MLLVERQSDALRNGHPILAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSTSD 8632 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R PLL+GS K+NIGH + Sbjct: 8633 VDAVEAHGTGTRLGDPIEAQALLATYGQDRPEGLPLLLGSIKSNIGHTQAAAGVAGIIKM 8692 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP+ L+ +TPS + WE + ++ E + W G+PR AGVSSFG +GTNAH Sbjct: 8693 IMAMRHGVLPQTLHVDTPSTQVEWEAGDVSLLTEAMDWPETGRPRRAGVSSFGISGTNAH 8752 Query: 433 VILEEAPAVG---TPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQAR 487 I+E+ P + PA T P+ V+P LSA+ +AL A E + L A P R Sbjct: 8753 TIIEQPPVLERAEAPAATVPLP------VVPWVLSAKGEDALRAQARELQAHLLAAPDVR 8806 Query: 488 LADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLF 547 DV+ + RA E RAA+V RE + L ALA+ R LV G S A K A+LF Sbjct: 8807 PVDVAWSLAANRASFEDRAAVVAADREGLLAGLAALAEGRSTAALVEG-SPVAGKLAFLF 8865 Query: 548 TGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRH 607 TGQGSQ GM REL++ PVFA + E + LE PL DV+F G + L Sbjct: 8866 TGQGSQRLGMGRELYEAYPVFAAALDAVCEQLN--LELPLKDVLF------GTNAALLDE 8917 Query: 608 TTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGR 667 T Y QPALFAVE+ L RL +SWG PD + GHS+G+ +AA VAGVF +ED L+A RGR Sbjct: 8918 TRYTQPALFAVEVALFRLVESWGIRPDFLSGHSIGEIAAAHVAGVFSLEDACTLVAARGR 8977 Query: 668 LFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVA 726 L +LP+GG M AV + + LTD +S+AA NG +V+ +D+ A+A A Sbjct: 8978 LMQALPSGGVMIAVEASEDEVLPLLTDR---VSIAAVNGPRSVVIAGDEDVAVALAESFA 9034 Query: 727 DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGA 786 D + L SHAFHS +D +LD+F + L + P+ ++ N TG+ + Sbjct: 9035 DR-KSKRLTVSHAFHSPHMDGMLDEFRQVVEGLSFETPRIQIVSNLTGAPV-TDEMASAE 9092 Query: 787 YWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPT 846 +W RH R V F +R L D LE+GP VL+A A+ P Sbjct: 9093 FWVRHVRDAVRFLDGIRALEDAGVTTYLELGPGGVLSAMGQECLTGEG------AAFVPV 9146 Query: 847 TADHRQITEAVAAAYAAGHLPDFRA-----FRQPDARKLDLPTYPFEHRQFWFSDNRAID 901 + R TEA+ AA A H+ + F DAR ++LPTY F+ +++W + Sbjct: 9147 MRNGRPETEAMVAAAALAHVRGLKVNWSQFFVGSDARSVELPTYAFQRQRYWLQ----MA 9202 Query: 902 RDTQTASAGSVTPHRTQAVRLLEDGQIEELAALID--GETVDEQTLRVLNKLAARHNQQR 959 T++ +A + AV E +E LAA +D E + L L L+A R Sbjct: 9203 GVTRSGAADELDSRFWDAV---EREDMESLAATLDMDDENAWDTVLPALPTLSAWRRGLR 9259 Query: 960 STHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVALP 1019 + RY + W + D AA + + + +V +P Sbjct: 9260 TQSEVDRWRYRVSWKP----------------LTDAAAAGVRLSGSW--------LVVVP 9295 Query: 1020 GSDADEAQLVDTLRAASAGELYVVHIAAGD--------GAAAPMRDLLRVQHRT-LGGLR 1070 D+ +V+ L A VV A D G+ A + LL + + Sbjct: 9296 SEGVDDTTVVEALVGRGAEVRRVVVEAGADRAGLFSDVGSVAGVVSLLALDEAAGVVATA 9355 Query: 1071 RLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPE-QSCLWGFGRAAALELPHIWGGLADL 1129 L +A DA + +P+W +TR V +D +V Q+ WG GR AALELP WGGL DL Sbjct: 9356 SLVQALGDAGVEAPLWCLTRGAVSVGRSDRLVSAVQAQTWGLGRVAALELPERWGGLVDL 9415 Query: 1130 SGADTEWPRLIARITS--PRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLV 1187 E R +AR+ GEDQ+A+R V+ RLVR TG + + P T LV Sbjct: 9416 PEVWDE--RAMARLVGVLAGSGEDQVAVRSSGVFGRRLVRATGGDTGSWTP---SGTVLV 9470 Query: 1188 TGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADA 1247 TGG GA+G VA +LA GA +VLTSRR + DV V+ D AD Sbjct: 9471 TGGTGALGGRVARWLAGAGAERLVLTSRRGADAPGAAELTAELTELGVDVSVVACDAADR 9530 Query: 1248 HDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTD 1307 L T +AAE L +VH AG + L L + V K A +L E + Sbjct: 9531 D---ALRTLLAAEADTLTAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHELTVE 9587 Query: 1308 LRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG-- 1365 L +L FV SS++ + G GQ Y AANA+LD LA + R G+ A S+ +GPWA G Sbjct: 9588 LGIELSAFVLFSSMSGMTGAAGQANYAAANAYLDALAEQRRAAGLAATSLAWGPWAEGGM 9647 Query: 1366 MADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQG--VVAKIDWSRFLPLYQQAGRRA 1423 AD AR+ + G+ ++P A+A + VA +VA +DW RF P + + Sbjct: 9648 AADEAMDARMRREGLPPMAPDTAMAVLRRSVASSSDAALLVADVDWERFGPAFTVVRPSS 9707 Query: 1424 FLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVD- 1482 +EL +EL VE+ + + + +R VA V + Sbjct: 9708 LFAEL-AELAEVRPAGPVARTAGGAGSPVERFAGLGAVELERELLGLVRTHVAAVLGHEG 9766 Query: 1483 ADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGL 1542 A+ + E F +LG DSL AVELR R+ G +P TL+ D+P S +L E+LG Sbjct: 9767 AETVGAERAFKELGFDSLTAVELRNRLGAATGVSLPATLIFDYPTASAITAFLRDELLGS 9826 Query: 1543 GEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDR-WD 1600 Q A VTA DDPIA+VA+SCRFPG PE W+LLA G DAI E P DR WD Sbjct: 9827 EVQMT---APVVTAVADDPIAIVAMSCRFPGGVRTPEDLWQLLAAGGDAIGEFPVDRGWD 9883 Query: 1601 IDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLE 1660 +D Y PDPD G Y R FFGISPREA+ ++PQQRL+LET WE E Sbjct: 9884 LDRLYSPDPDRQGTFYAREGGFLYDAADFDAVFFGISPREALAMDPQQRLLLETTWEAFE 9943 Query: 1661 RAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGF 1720 RAG APS +RGS+ GVF G +Y L A D IE TGNA + +SGR+++A G Sbjct: 9944 RAGIAPSSVRGSQAGVFIGTNGQDYGATLQALP-DGIEGFLGTGNAASVVSGRLSYAFGL 10002 Query: 1721 EGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVG 1780 EGPAV VDTACS++LVA+H A QAL++G+CD+ALAGGV V+ SP + SR R L+ G Sbjct: 10003 EGPAVTVDTACSASLVALHWAIQALRNGECDMALAGGVTVMSSPGAYIDFSRQRGLAADG 10062 Query: 1781 RCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGG 1840 R K F ADG EG G+L+++RLSDA R+G V AV+ S++NQDGAS+GLT PNG Sbjct: 10063 RIKAFSDDADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGSAINQDGASNGLTAPNGP 10122 Query: 1841 AQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSV 1900 +QQR+I A LA AGLS ++VD +EAHGTGT LGDPIE Q PLL+GS+ Sbjct: 10123 SQQRVIRAALASAGLSSSEVDAVEAHGTGTRLGDPIEAQALLATYGQERPADQPLLLGSI 10182 Query: 1901 KTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTN 1960 K+NIGHT++A+G AG++K+VL++QHGVLPQ+LH +PH+ W A V ++ E W Sbjct: 10183 KSNIGHTQAAAGVAGVMKMVLAMQHGVLPQTLHVNEATPHVDWSAGEVALLTERQAWPET 10242 Query: 1961 GRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL--ALSA 2018 GR RRAG+SSFGF+GTNAH +VE+AP + P V+ LS Sbjct: 10243 GRPRRAGISSFGFSGTNAHTIVEQAPDDIR---------EAASPVAPQQRPGVVPWVLSG 10293 Query: 2019 RSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXX 2078 ++ AL A R +++ L+ ADV ++ RS E RA +V Sbjct: 10294 KNEAALRAQAERLLAAVTSDELLEPADVAYSLATSRSALERRAVVVAGERDEFLAALRAL 10353 Query: 2079 XXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADML 2138 AGV G V +A+LFTGQGSQ GM REL+D PVFA + + L Sbjct: 10354 AAGEQAAGVAHGT-VSAGASAFLFTGQGSQRLGMGRELYDAFPVFADALDAICARMDGHL 10412 Query: 2139 PRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAA 2198 PL +VLF +D A LL T F QPALFA+E+ L RL +SW + PD + GHS+G+ AA Sbjct: 10413 ELPLKEVLFGSD---AALLDETRFTQPALFAIEVALFRLLESWGVRPDFLSGHSIGEIAA 10469 Query: 2199 ACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP 2258 A VAGVFSLDD L+A RGR+ +LP GG M+AV A E V + + RVS+ A NGP Sbjct: 10470 AHVAGVFSLDDACALVAARGRLMQALPAGGVMIAVQASEEEVLPLLTD--RVSIAAVNGP 10527 Query: 2259 NTVLSGPGED-LEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPT 2317 V+ ED + F D + L SHAFHS +D +L P Sbjct: 10528 EAVVVAGDEDAATAVAAAFPDR--KSKRLTVSHAFHSPHMDGMLADFRKVAESLSYESPR 10585 Query: 2318 LPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGA 2377 +P+V N TGA++T + A +W RH R+ V+F + +R + A G + +E+GP VL+ Sbjct: 10586 IPVVSNLTGALVTDEM-ASADFWVRHVREAVRFLDGIRVLEAAGVTTFVELGPDGVLSAL 10644 Query: 2378 AVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPT 2436 A + V +LRKG + + ALA A+V G D+ A + R V+LPT Sbjct: 10645 AQDCTEQDAL---FVPALRKGRPEAEAVVTALARAHVHGVTVDWTAFYSGTAARRVDLPT 10701 Query: 2437 YPFQRRRFW----PKASSIAVDGGTAA 2459 Y FQR+R+W P+ +++ G+ A Sbjct: 10702 YAFQRKRYWLEEAPRPAAVEPGAGSGA 10728 Score = 823 bits (2125), Expect = 0.0 Identities = 577/1491 (38%), Positives = 778/1491 (52%), Gaps = 90/1491 (6%) Query: 991 LVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDG 1050 L G A V E+ADA G +A D +V + A + VH A D Sbjct: 4474 LAGSTGAQVTEYADAAALGA----ALAAGEPAFDAVFVVPSAPVPGADVVGSVHTAVND- 4528 Query: 1051 AAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWG 1110 A A +++ L + L L A + G+ V D S + G Sbjct: 4529 ALAVVQEWLADERFAATRLVWLTSGA----------VAVGSGEGVRDL-----AGSAVRG 4573 Query: 1111 FGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTG 1170 R+A E P L D + L A + GE ++A+R V PRLVR Sbjct: 4574 LLRSAQSENP------GQLLMLDVDEASLGAVPAALAAGEFELAIRSGVVCVPRLVRVPS 4627 Query: 1171 EPS--DTPLPVREDR-TYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXX 1226 S D+P+ + + T LVTG G++G A +L + +GA ++L SRR P Sbjct: 4628 AESIGDSPVVLGDPSGTVLVTGATGSLGRLFARHLVTAYGAERLLLVSRRGPAADGADEL 4687 Query: 1227 XXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAE 1286 + ++ D+AD ++A L+ +V AE PL +VH AG + LS L Sbjct: 4688 IAELARLGAHAELVACDIADKGELAALLASVPAE-HPLTAVVHTAGVLDDGVLSSLTPER 4746 Query: 1287 VDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWR 1346 V V KV AW+L E DL L FV S A+ +G GQ Y AANAFL+ LA + Sbjct: 4747 VASVLRPKVDAAWNLHELTRDL--GLSAFVLFSGAAAAFGAAGQANYAAANAFLEALAEQ 4804 Query: 1347 LRERGVTAVSVNFGPWAA-------GMA---DAESRARLEQRGVRTLSPAEALAGMADVV 1396 R G+ AVS+ +G WA GMA D R+ + GV L E L G+ D Sbjct: 4805 RRAEGLAAVSLAWGLWAPQAGSSGEGMASRLDEVDLRRIARDGVGALGAEEGL-GLFDTA 4863 Query: 1397 AGPVQGVVAKI--DWSRFLPLYQQAGRR-AFLSELESELXXXXXXXXXXXXXXXXXXLVE 1453 V+ I D + AG A L L LV Sbjct: 4864 MTVDSAVLMPIHLDLAVLRAQAVSAGSTPALLKGLVRVPARRTLERRTGGGADAGSPLVA 4923 Query: 1454 QLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQG 1512 +L PV + + ++ + + VA V AD + E F DLG DSL AVELR ++ Sbjct: 4924 RLLALPVAEHEGVLLDLVCGRVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKAE 4983 Query: 1513 VGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTAR-----TDDPIAVVAV 1567 G +P TL+ D+P A +LL E+ G+ V+ V R TDDPI +V + Sbjct: 4984 TGLRLPPTLIFDYPTPVALARHLLAELAVTGD-LEVQDGVRVPVRAAVDVTDDPIVIVGM 5042 Query: 1568 SCRFPGAP-DPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXX 1625 CR+PG PE W+L+A G D + P DR W+++ Y PDPD G +YTR Sbjct: 5043 GCRYPGGVRSPEELWQLVATGGDGVTTFPSDRGWNVEALYHPDPDHAGTSYTREGGFLHD 5102 Query: 1626 XXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEY 1685 P FFGISPREA+ ++PQQRL+LET WE ERAG P+ LRGSRTGVF GV ++Y Sbjct: 5103 VADFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGVMYHDY 5162 Query: 1686 AHLL-------SAESIDK-IEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVA 1737 S +++ + +E + TGNA + SGR+A+ G EGPAV VDTACSS+LVA Sbjct: 5163 VTGFGLGDGAGSGDALPEGVEGYLGTGNAGSIASGRIAYTFGLEGPAVTVDTACSSSLVA 5222 Query: 1738 VHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEG 1797 +H A QAL+ G+CD+ALAGGV V+ +P T V SR R LS GRCK+F A+ADG +EG Sbjct: 5223 LHWAIQALRGGECDMALAGGVAVMATPETFVDFSRQRGLSADGRCKSFAAAADGTGWAEG 5282 Query: 1798 CGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSG 1857 G+L+++R SDA+R+G + AV+ S+VNQDGAS+GLT PNG +QQR+I LA AGLS Sbjct: 5283 AGMLLVERQSDALRNGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIREALASAGLSA 5342 Query: 1858 ADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLI 1917 DVD +EAHGTGT LGDPIE Q PLL+GS+K+NIGHT++A+G AG+I Sbjct: 5343 VDVDAVEAHGTGTRLGDPIEAQALLATYGQDRPEGRPLLLGSIKSNIGHTQAAAGVAGII 5402 Query: 1918 KVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTN 1977 K+V++++HGVLPQ+LH + PS + W+A V ++ + + W GR RRAG+SSFG +GTN Sbjct: 5403 KMVMAMRHGVLPQTLHVDAPSTQVEWEAGDVSLLTQAMDWPQTGRPRRAGISSFGISGTN 5462 Query: 1978 AHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV-LALSARSPEALVELARRYDDWLS 2036 AH ++E+ PP L P V LSA+ +AL AR+ ++ Sbjct: 5463 AHTIIEQ-PPVLERAEPEAAALL----------PAVPWVLSAKGEDALRAQARQLHSHVA 5511 Query: 2037 ATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRP 2096 +TPG DV + R+ FE RAA+V + A +V G V Sbjct: 5512 STPGARPVDVAWSLAANRASFEDRAAVVAADREGLLAGLAALAEGRSTATLVEGSPV-AG 5570 Query: 2097 TTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADL 2156 A+LFTGQGSQ GM REL++ PVFA + E + L PL +VLF DRE + Sbjct: 5571 KLAFLFTGQGSQRLGMGRELYEAYPVFAAALDAVCERLD--LELPLKEVLFGNDRE---V 5625 Query: 2157 LQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAE 2216 L T F QPALFAVE+ L RL +SW + D + GHSVG+ AAA VAGVFSLDD L+A Sbjct: 5626 LDRTEFTQPALFAVEVALFRLLESWGVRADFLSGHSVGEIAAAHVAGVFSLDDACALVAA 5685 Query: 2217 RGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLE-EIVER 2275 RGR+ +LPEGG M+AV A + V + E RVS+ A NGP +V+ ED + Sbjct: 5686 RGRLMQALPEGGVMIAVQASEDEVLPLLTE--RVSIAAINGPRSVVVAGDEDAALAVAAA 5743 Query: 2276 FEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPL 2335 F D + L SHAFHS +D +LD P +PLV N TGA++ + Sbjct: 5744 FPDR--KSKRLTVSHAFHSPHMDGMLDDFRRVVEGLSFQAPRIPLVSNLTGALIADEMG- 5800 Query: 2336 DAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASL 2395 A++W RH R+ V+F + VR + G + +E+GP VL+ A Q A V L Sbjct: 5801 SAEFWVRHVREAVRFLDGVRALEGAGVTSFVELGPDGVLS-ALAQDCLAGDADVAFVPVL 5859 Query: 2396 RKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFW 2445 R G + + A+A A+V G D++A R VELPTY FQR+R+W Sbjct: 5860 RAGRGEAETLVTAVAQAHVRGVEVDWSAFFAGTGARSVELPTYAFQRQRYW 5910 Score = 811 bits (2095), Expect = 0.0 Identities = 535/1339 (39%), Positives = 726/1339 (54%), Gaps = 60/1339 (4%) Query: 1149 GEDQIALRGDAVYAPRLVRRTGEPS--DTPLPVREDR-TYLVTGGLGAIGLEVAGYLAS- 1204 GE ++A+R V PRLVR S D+P+ + + T LVTG G +G A +L + Sbjct: 7898 GEFELAIRSGVVCVPRLVRVPSAESTGDSPVVLGDPSGTVLVTGATGGLGRLFARHLVTA 7957 Query: 1205 HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPL 1264 +GA ++L SRR P + ++ D+AD + L+ +V AE PL Sbjct: 7958 YGAERLLLVSRRGPAADGADELIAELARLGAHAELVACDIADREALGALLASVPAE-HPL 8016 Query: 1265 AGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASV 1324 +VH AG + LS L V V KV AW+L E DL DL FV S A+ Sbjct: 8017 TAVVHTAGVLDDGVLSSLTPDRVASVLRPKVDAAWNLHELTRDL--DLSAFVLFSGAAAA 8074 Query: 1325 WGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAA-------GMA---DAESRAR 1374 +G GQ Y AANAFL+ LA + R G+ A S+ +G WA GMA D R Sbjct: 8075 FGAAGQANYAAANAFLEALAEQRRAEGLPAASLAWGLWAPQTGSSGEGMAARLDEADLRR 8134 Query: 1375 LEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQ--QAGRRAFLSELESEL 1432 + + GV L E L G+ D V+ I + Q AG L + Sbjct: 8135 IARDGVGALGAEEGL-GLFDTAMTVDSAVLMPIHLDLAVLRAQAISAGSPPALLRALVRV 8193 Query: 1433 XXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAG 1491 L +L PV + + ++ + + VA V AD + E Sbjct: 8194 PARRTATRGDGGTESGSPLTARLLALPVAEHEGVLLDLVCGRVAAVLGHTGADAVDAERA 8253 Query: 1492 FFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGL----GEQTN 1547 F DLG DSL AVELR ++ G +P TL+ D+P + A +LL E LG+ G+Q Sbjct: 8254 FRDLGFDSLTAVELRNVLKTETGLRLPPTLIFDYPTPAALARHLLSE-LGVTGASGDQDG 8312 Query: 1548 VRQAST----VTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDI 1601 R T V TDDPI +V + CR+P G PE W+L+A G D + P DR W++ Sbjct: 8313 SRGVLTPVRAVVDVTDDPIVIVGMGCRYPGGVRTPEELWQLVASGGDGVTAFPTDRGWNV 8372 Query: 1602 DEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLER 1661 + Y PDPD G +YTR FFGISPREA+ ++PQQRL+LET WE ER Sbjct: 8373 EALYHPDPDHVGTSYTREGGFLHDVAEFDAAFFGISPREALAMDPQQRLLLETSWEAFER 8432 Query: 1662 AGYAPSDLRGSRTGVFTGVAANEYA--HLLSAESIDKIEPHFITGNALNAISGRVAFALG 1719 AG P+ LRGSRTGVF GV ++YA + E + +E + TGN+ + SGRV++A G Sbjct: 8433 AGIDPATLRGSRTGVFAGVMYHDYATGYGNGEELPEGVEGYLGTGNSGSIASGRVSYAFG 8492 Query: 1720 FEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPV 1779 EGPAV VDTACSS+LVA+H A QAL+ G+CD+ALAGGV V+ +P T V SR R LS Sbjct: 8493 LEGPAVTVDTACSSSLVALHWAIQALRGGECDMALAGGVAVMATPETFVDFSRQRGLSAD 8552 Query: 1780 GRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNG 1839 GRCK+F A+ADG +EG G+L+++R SDA+R+G + AV+ S++NQDGAS+GLT PNG Sbjct: 8553 GRCKSFAAAADGTGWAEGAGMLLVERQSDALRNGHPILAVVRGSAINQDGASNGLTAPNG 8612 Query: 1840 GAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGS 1899 +QQR+I LA AGLS +DVD +EAHGTGT LGDPIE Q PLL+GS Sbjct: 8613 PSQQRVIRQALASAGLSTSDVDAVEAHGTGTRLGDPIEAQALLATYGQDRPEGLPLLLGS 8672 Query: 1900 VKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT 1959 +K+NIGHT++A+G AG+IK++++++HGVLPQ+LH + PS + W+A V ++ E + W Sbjct: 8673 IKSNIGHTQAAAGVAGIIKMIMAMRHGVLPQTLHVDTPSTQVEWEAGDVSLLTEAMDWPE 8732 Query: 1960 NGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV-LALSA 2018 GR RRAGVSSFG +GTNAH ++E+ PP L T P V LSA Sbjct: 8733 TGRPRRAGVSSFGISGTNAHTIIEQ-PPVLE---------RAEAPAATVPLPVVPWVLSA 8782 Query: 2019 RSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXX 2078 + +AL AR L A P + DV + R+ FE RAA+V Sbjct: 8783 KGEDALRAQARELQAHLLAAPDVRPVDVAWSLAANRASFEDRAAVVAADREGLLAGLAAL 8842 Query: 2079 XXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADML 2138 + A +V G V A+LFTGQGSQ GM REL++ PVFA + E + L Sbjct: 8843 AEGRSTAALVEGSPV-AGKLAFLFTGQGSQRLGMGRELYEAYPVFAAALDAVCEQL--NL 8899 Query: 2139 PRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAA 2198 PL DVLF T+ A LL T + QPALFAVE+ L RL +SW I PD + GHS+G+ AA Sbjct: 8900 ELPLKDVLFGTN---AALLDETRYTQPALFAVEVALFRLVESWGIRPDFLSGHSIGEIAA 8956 Query: 2199 ACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP 2258 A VAGVFSL+D L+A RGR+ +LP GG M+AV A + V + + RVS+ A NGP Sbjct: 8957 AHVAGVFSLEDACTLVAARGRLMQALPSGGVMIAVEASEDEVLPLLTD--RVSIAAVNGP 9014 Query: 2259 NTVLSGPGEDLE-EIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPT 2317 +V+ ED+ + E F D + L SHAFHS +D +LD P Sbjct: 9015 RSVVIAGDEDVAVALAESFADR--KSKRLTVSHAFHSPHMDGMLDEFRQVVEGLSFETPR 9072 Query: 2318 LPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGA 2377 + +V N TGA +T + A++W RH R V+F + +R + G + +E+GP VL+ Sbjct: 9073 IQIVSNLTGAPVTDEM-ASAEFWVRHVRDAVRFLDGIRALEDAGVTTYLELGPGGVLSAM 9131 Query: 2378 AVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVH-RQPRRPVELPT 2436 + AA V +R G + + A A A+V G + +++ R VELPT Sbjct: 9132 GQECLTGEGAA--FVPVMRNGRPETEAMVAAAALAHVRGLKVNWSQFFVGSDARSVELPT 9189 Query: 2437 YPFQRRRFWPKASSIAVDG 2455 Y FQR+R+W + + + G Sbjct: 9190 YAFQRQRYWLQMAGVTRSG 9208 Score = 778 bits (2008), Expect = 0.0 Identities = 450/1011 (44%), Positives = 590/1011 (58%), Gaps = 32/1011 (3%) Query: 1465 SLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMD 1524 SL+T LR+A T +D + F DLG DSL AV+L R+ G G +PVTL D Sbjct: 93 SLVTASLRDAAP--TALDP-----QRSFLDLGFDSLAAVDLHARLVAGTGLRLPVTLAFD 145 Query: 1525 HPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPG-APDPESFWEL 1583 HP + A + +LGL + +++ D+PIA+V + CRFPG PE+ WEL Sbjct: 146 HPTPAHLARRIHALLLGLTAPAEAPVTAAISS--DEPIAIVGIGCRFPGDVHSPEALWEL 203 Query: 1584 LAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAV 1642 +A G DAI E P R W++D YDPDPD G TY R FFGISPREA+ Sbjct: 204 VANGTDAISEFPTGRGWNLDSLYDPDPDRAGTTYAREGGFLHDADEFDAAFFGISPREAL 263 Query: 1643 WIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFI 1702 ++PQQRL+LET WE +RAG PS LRG + GVF G EY L ++ D E + + Sbjct: 264 AMDPQQRLLLETSWEAFDRAGIDPSGLRGGQIGVFVGAETQEYGPRLE-DAADGFEGYLV 322 Query: 1703 TGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLL 1762 TGNA + SGR+A+ GFEGP V VDTACSS+L A+H A QAL+SG+C LALAGGV ++ Sbjct: 323 TGNAASVASGRIAYTFGFEGPTVTVDTACSSSLAALHLAVQALRSGECSLALAGGVAIMA 382 Query: 1763 SPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPA 1822 SP + V+ SR R L+P GRCK F A ADG EG G+L+++RLSDA G + AV+ Sbjct: 383 SPGSFVSFSRQRGLAPDGRCKPFAAGADGTAWGEGAGMLLVERLSDARAAGHHILAVVRG 442 Query: 1823 SSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXX 1882 +++NQDGAS+GLT P+G AQQR+I LA AGL+ ADVD +EAHGTGT LGDPIE Q Sbjct: 443 TAINQDGASNGLTAPSGPAQQRVIRQALANAGLTSADVDAVEAHGTGTTLGDPIEAQALL 502 Query: 1883 XXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIP 1942 PL +GS+K+NIGHT++A+G AG+IK+V++++HGVLPQ+LH + P+PH+ Sbjct: 503 ATYGQDRPADRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPQTLHVDAPTPHVD 562 Query: 1943 WDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXX 2002 W+A V ++ +PV W T RRAGVSSFG +GTNAH ++EE PP Sbjct: 563 WEAGAVSLLTQPVAWPTADAPRRAGVSSFGMSGTNAHAIIEE-PPTEDAAQHTEDQPPAQ 621 Query: 2003 XXXGTDDSPQVL--------ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGR 2054 TD+ ALSA++PEAL ARR DWL P AD+ H+ R Sbjct: 622 EAPATDEPEAAADQLPLLPWALSAKTPEALRATARRLGDWLDTHPDATPADIGHSLATTR 681 Query: 2055 SHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGE-HVHRPTTAWLFTGQGSQYPGMA 2113 S FE+RA ++ D V+ GE RP A LFTGQGSQ M Sbjct: 682 SRFEHRAVVLGDDRTALQRGLRALAEAADTPAVIHGEPGAGRP--AVLFTGQGSQRLAMG 739 Query: 2114 RELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEM 2172 REL++T PVFA + + + + L PLLDVLFA D A LL T++ QPALFAVE+ Sbjct: 740 RELYETYPVFADALDDASWYLDEQLEHPLLDVLFADEDTPEAALLHQTAYTQPALFAVEV 799 Query: 2173 GLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVA 2232 L RL +SW + P V GHSVG+ AAA VAGVF+L+D L+A RGR+ +LP GG M+A Sbjct: 800 ALYRLVESWGLRPAFVAGHSVGEIAAAHVAGVFTLEDACALVAARGRLMQALPTGGVMIA 859 Query: 2233 VFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLE-EIVERFEDEGIRCTWLATSHA 2291 V A + V + + RVS+ A NGP +V+ ED + E FE +G + L SHA Sbjct: 860 VQASEDEVLPLLTD--RVSIAAINGPQSVVVAGDEDAALAVAEAFEAQGRKTKRLTVSHA 917 Query: 2292 FHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFA 2351 FHS +D +LD PTLP+V TG T ++W RH R+ V+F Sbjct: 918 FHSPHMDAMLDAFRRVAQVLDYGTPTLPVVSLLTGTTATAAELASPEHWVRHVREAVRFL 977 Query: 2352 ESVRTVAALGCSVLMEIGPQPVLTGAA---VQVWPEHMAAPRAVASLRKGVADRRQIADA 2408 + VRT+ A G +E+GP PVLT A + P+ P A+LR G + + DA Sbjct: 978 DGVRTLRARGADSFLELGPDPVLTAMAQDCLVTDPQDTTNPVFAAALRSGRPEPTTLLDA 1037 Query: 2409 LASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSIAVDGGTA 2458 +A +V G D+AA R VELPTY FQR+R+W A + A + T+ Sbjct: 1038 VARMFVRGAETDWAAYFAGTGARSVELPTYAFQRQRYWMNARTPATEPATS 1088 Score = 655 bits (1691), Expect = 0.0 Identities = 412/1036 (39%), Positives = 566/1036 (54%), Gaps = 34/1036 (3%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + RFPG + E+ W LL G +AI + P DR WD++ + PDP G R Sbjct: 9844 AIVAMSCRFPGGVRTPEDLWQLLAAGGDAIGEFPVDRGWDLDRLYSPDPDRQGTFYAREG 9903 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE MDPQ R+L+ET W A E +GIAP+S+ S GVF+G Sbjct: 9904 GFLYDAADFDAVFFGISPREALAMDPQQRLLLETTWEAFERAGIAPSSVRGSQAGVFIGT 9963 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 DY A+ + IE ++ G + + +GR+SY GL+GPAV VDTACS+SLVA+H Sbjct: 9964 NGQDY--GATLQALPDGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSASLVALH 10021 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR ECD+ALAGG V+ +P I FS LA DGR K F ADG GEG G Sbjct: 10022 WAIQALRNGECDMALAGGVTVMSSPGAYIDFSRQRGLAADGRIKAFSDDADGTGWGEGVG 10081 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DA R+G + AV+RGSAINQDGAS GLT PNG +QQRVI AL AGL ++ Sbjct: 10082 MLLVERLSDARRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRAALASAGLSSSE 10141 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R ++PLL+GS K+NIGH + Sbjct: 10142 VDAVEAHGTGTRLGDPIEAQALLATYGQERPADQPLLLGSIKSNIGHTQAAAGVAGVMKM 10201 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 +++ LP+ L+ +PH+ W + ++ E W G+PR AG+SSFGF+GTNAH Sbjct: 10202 VLAMQHGVLPQTLHVNEATPHVDWSAGEVALLTERQAWPETGRPRRAGISSFGFSGTNAH 10261 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQARLAD 490 I+E+AP A + PV +R V+P LS + AL A + + AD Sbjct: 10262 TIVEQAPDDIREAAS-PVAPQQRPGVVPWVLSGKNEAALRAQAERLLAAVTSDELLEPAD 10320 Query: 491 VSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQ 550 V+++ T+R+ LE+RA +V R+ + L ALA A G+ G + A +A+LFTGQ Sbjct: 10321 VAYSLATSRSALERRAVVVAGERDEFLAALRALAAGEQAAGVAHG-TVSAGASAFLFTGQ 10379 Query: 551 GSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTY 610 GSQ GM REL+D PVFA+ + + LE PL +V+F +D + L T + Sbjct: 10380 GSQRLGMGRELYDAFPVFADALDAICARMDGHLELPLKEVLFGSDA------ALLDETRF 10433 Query: 611 AQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFG 670 QPALFA+E+ L RL +SWG PD + GHS+G+ +AA VAGVF ++D L+A RGRL Sbjct: 10434 TQPALFAIEVALFRLLESWGVRPDFLSGHSIGEIAAAHVAGVFSLDDACALVAARGRLMQ 10493 Query: 671 SLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVADGV 729 +LPAGG M AV + E LTD +S+AA NG V+ +D +AVA D Sbjct: 10494 ALPAGGVMIAVQASEEEVLPLLTDR---VSIAAVNGPEAVVVAGDEDAATAVAAAFPDR- 10549 Query: 730 RCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWR 789 + L SHAFHS +D +L DF A+ L Y P+ ++ N TG AL +W Sbjct: 10550 KSKRLTVSHAFHSPHMDGMLADFRKVAESLSYESPRIPVVSNLTG-ALVTDEMASADFWV 10608 Query: 790 RHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTAD 849 RH R+ V F +R L +E+GP VL+A A A L RP + Sbjct: 10609 RHVREAVRFLDGIRVLEAAGVTTFVELGPDGVLSALAQDCTEQDALFVPALRKGRP---E 10665 Query: 850 HRQITEAVAAAYAAGHLPDFRAFRQPDA-RKLDLPTYPFEHRQFWFSDNRAIDRDTQTAS 908 + A+A A+ G D+ AF A R++DLPTY F+ +++W + A Sbjct: 10666 AEAVVTALARAHVHGVTVDWTAFYSGTAARRVDLPTYAFQRKRYWLEEAPRPAAVEPGAG 10725 Query: 909 AGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDAR 968 +G+V +++ ++ LAA ++ + D+ VL L+A ++ V R Sbjct: 10726 SGAVVD--APFWEAVDNADLDALAATLEIDA-DQPLSAVLPALSAWRRRRADRSVVDGWR 10782 Query: 969 YEIRWDXXXXXXXXXXXXXDWILVGDDTAA------VLEFADALTAGGHRHQIVALPGSD 1022 Y + W W++V T A + E ADAL A G + VAL + Sbjct: 10783 YGVTWKPLGEPDGSRPSGT-WLVVTAATTAETAGSGLPEIADALRAQGVDVREVALDAAA 10841 Query: 1023 ADEAQLVDTLRAASAG 1038 D A + + L AA AG Sbjct: 10842 TDRAVVAERLDAALAG 10857 Score = 639 bits (1648), Expect = e-180 Identities = 376/896 (41%), Positives = 509/896 (56%), Gaps = 20/896 (2%) Query: 3 SAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPD 60 +A P++ P AI+ + RFPG + E+ W LL G +AI + P DR WD++ ++PD Sbjct: 6540 TAVTPVDDDP-IAIVAMSCRFPGGVRTPEDLWQLLAAGGDAIGEFPVDRGWDLDRLYNPD 6598 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P G R GF+ D FDA FFG+S RE MDPQ R+L+ET W E +GI P + Sbjct: 6599 PDQQGTFYAREGGFLYDAADFDADFFGISPREALAMDPQQRLLLETTWETFERAGIDPAA 6658 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 + S GVF+G DY A+ IE ++ G + + +GR+SY GL+GPAV V Sbjct: 6659 VRGSQAGVFIGTNGQDY--DATFHSVPDGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTV 6716 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACS+SLVA+H A QALR ECD+ALAGG V+ +P I FS LA DGR K F A Sbjct: 6717 DTACSASLVALHWAIQALRGGECDMALAGGVTVMSSPGAYIDFSRQRGLAEDGRIKAFSA 6776 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 ADG GEG G+++V+RL DA R+G + AV+RGSAINQDGAS GLT PNG +QQRVI Sbjct: 6777 DADGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIR 6836 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 AL AGL A+V +EAHGTGT LGDPIEAQA G RA E+PLL+GS K+NIGH Sbjct: 6837 AALASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQERAEEQPLLLGSIKSNIGHT 6896 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 + +++ LP+ L+ P+PH+ W + ++ E W G+PR AG Sbjct: 6897 QAAAGVAGVIKMVLAMQHGVLPQTLHVNEPTPHVDWSAGEVALLTEQRDWPETGRPRRAG 6956 Query: 421 VSSFGFAGTNAHVILEEAPAV-GTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDW 479 +SSFGF+GTNAH I+E+AP V + +P E P LSA+ AL A Sbjct: 6957 ISSFGFSGTNAHTIIEQAPDVLDVEPSVQPQERPGGVLPWVLSAKNEAALRVQAERLLAA 7016 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHE 539 + + ADV+++ T+R+ LE+RA +V R+ + L ALA G+ G + Sbjct: 7017 VTSDELLEPADVAYSLATSRSALERRAVVVAGERDEFLAALRALAAGEQTAGVAHGTA-A 7075 Query: 540 APKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDG 599 TA+LFTGQGSQ GM REL+D PVFA+ + + LE PL +V+F +D Sbjct: 7076 VGGTAFLFTGQGSQRLGMGRELYDAHPVFADALDAICARMDGHLELPLKEVLFGSD---- 7131 Query: 600 DTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGA 659 + L T Y QPALFAVE+ L RL +SWG PD + GHS+G+ +AA VAGV ++D Sbjct: 7132 --AAVLDRTEYTQPALFAVEVALFRLVESWGIRPDFLSGHSIGEIAAAHVAGVLSLDDAC 7189 Query: 660 RLIAERGRLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTVLSGPAKDLE 718 L+A RGRL +LP+GG M AV + E LTD +S+AA NG +V+ +D Sbjct: 7190 ALVAARGRLMQALPSGGVMIAVEASEEEVLPLLTDR---VSIAAVNGPRSVVIAGDEDAA 7246 Query: 719 SAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALG 778 A+A AD + L SHAFHS +D +L+DF L + P+ ++ N TG AL Sbjct: 7247 VALAESFADR-KSKRLTVSHAFHSPHMDGMLEDFRQVVAGLSFEAPRIPVVSNLTG-ALV 7304 Query: 779 RSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQ 838 +W RH R+ V F +R L +E+GP VL+A A D + Sbjct: 7305 TDEMGSAEFWVRHVREAVRFLDGIRVLEAAGVTAYVELGPDGVLSALAQGCLADENSNAL 7364 Query: 839 VLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFW 893 + +LR + + + A+A G D+ A F AR++DLPTY F+ ++FW Sbjct: 7365 FMPALRKGRPEAETLVTTLGQAHAHGVEVDWSAYFAGSGARRVDLPTYAFQRQRFW 7420 Score = 181 bits (460), Expect = 1e-42 Identities = 133/375 (35%), Positives = 179/375 (47%), Gaps = 30/375 (8%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G A +LA G +VLTSRR D E+ + A D Sbjct: 1351 LITGGTGALGGRVARWLAGAGVERLVLTSRRGLDAPGAA---ELVAELGVDLSVVACDAA 1407 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXXX 3415 D + LLA AE L + H AGVLDD +L A PERF + L KA A H Sbjct: 1408 DRDALRALLA---AEAEGLTAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHELT 1464 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQANYA ANA LD L +RRA GL AT I +GPW +G Sbjct: 1465 GELGIELSAFVLFSSMSGSIGAAGQANYAAANAYLDALAEQRRAAGLAATSIAWGPWAEG 1524 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSAR-- 3533 GMA+ EA A + +G+ P+ P +A+ ALA+ + G TV W R + V+ + R Sbjct: 1525 GMAADEAMDARMRREGVPPMAPDSAIAALAQAVGAGEAALTVADIAWDRFSSVVAAVRPN 1584 Query: 3534 PPILDLVLPSAAGEA--TGDSELL----------KQLMEIPIPQRAGFVTEFLQREVQNF 3581 P + D ++ G A TG ++ +L E+P ++ + ++ V Sbjct: 1585 PSVADFATAASQGAASVTGQGTVVTGADVAGAAFAKLAELPRAEQDRELLGLVRTHVAAV 1644 Query: 3582 LRL--ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 L A A F +LG DSL A++LRNRL + + AT V+DYPT LAEYL Sbjct: 1645 LGHDGADAVGAERAFKELGFDSLTAVDLRNRLGA--ATALRLPATLVYDYPTSSALAEYL 1702 Query: 3640 VGQL----PDAEAPE 3650 G+L P A++P+ Sbjct: 1703 RGELMGNAPKADSPQ 1717 Score = 174 bits (442), Expect = 2e-40 Identities = 132/370 (35%), Positives = 170/370 (45%), Gaps = 21/370 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHTYAADV 3356 L+TGG GA+G A +LA GA +VLTSRR D A E+TE + A D Sbjct: 9469 LVTGGTGALGGRVARWLAGAGAERLVLTSRRGADAPGAAELTAELTELG-VDVSVVACDA 9527 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXX 3414 D + LLA AE L + H AGVLDD +L A PERF + L KA A H Sbjct: 9528 ADRDALRTLLA---AEADTLTAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHEL 9584 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQANYA ANA LD L +RRA GL AT + +GPW + Sbjct: 9585 TVELGIELSAFVLFSSMSGMTGAAGQANYAAANAYLDALAEQRRAAGLAATSLAWGPWAE 9644 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQA-TVLKANWQRAAKVLGSAR 3533 GGMA+ EA A + +GL P+ P A+ L +A+ S A V +W+R R Sbjct: 9645 GGMAADEAMDARMRREGLPPMAPDTAMAVLRRSVASSSDAALLVADVDWERFGPAFTVVR 9704 Query: 3534 PPILDLVLPSAAG-EATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL-------- 3584 P L L A G P+ + AG L+RE+ +R Sbjct: 9705 PSSLFAELAELAEVRPAGPVARTAGGAGSPVERFAGLGAVELERELLGLVRTHVAAVLGH 9764 Query: 3585 --ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 A A F +LG DSL A+ELRNRL + G ++ AT +FDYPT + +L + Sbjct: 9765 EGAETVGAERAFKELGFDSLTAVELRNRLGAATG--VSLPATLIFDYPTASAITAFLRDE 9822 Query: 3643 LPDAEAPETA 3652 L +E TA Sbjct: 9823 LLGSEVQMTA 9832 Score = 168 bits (425), Expect = 2e-38 Identities = 125/368 (33%), Positives = 163/368 (44%), Gaps = 30/368 (8%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G A +LA G +VLTSRR D + + A D Sbjct: 6178 LVTGGTGALGGRVARWLAGAGVERLVLTSRRGLDAPGAAELVAELSGLGVDVSVVACDAA 6237 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXXX 3415 D + LL AE L + H AGVLDD +L A PERF L KA A H Sbjct: 6238 DRDALRVLL---EAEAEGLTAVVHTAGVLDDGVLDALTPERFEGVLRAKATSALNLHELT 6294 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQ NYA ANA LD L +RRA GL AT + +GPW +G Sbjct: 6295 GELGIELSAFVLFSSMSGMTGAAGQGNYAAANAYLDALAEQRRAAGLAATSLAWGPWAEG 6354 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAE-VIANGSGQATVLKANWQRAAKVLGSARP 3534 GMA+ EA A + +GL P+ P A+ L + V+ + V +W R ARP Sbjct: 6355 GMAADEAMDARMRREGLPPMAPDTAMAVLRQSVVPSSDAALLVADVDWDRFGPAFTVARP 6414 Query: 3535 PILDLVL----PSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL------ 3584 L L P+A G ATG + + AG L+RE+ +R Sbjct: 6415 STLFAELSETRPAAEGAATGTG--------TSVDRFAGLAAVELERELLGLVRTHVAAVL 6466 Query: 3585 ----ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV 3640 A A F +LG DSL A+ELRNRL + G ++ AT +FDYPT + +L Sbjct: 6467 GHEGAETVGAERAFKELGFDSLTAVELRNRLGAATG--VSLPATLIFDYPTASAITAFLR 6524 Query: 3641 GQLPDAEA 3648 +L +A Sbjct: 6525 DELLGTQA 6532 Score = 153 bits (386), Expect = 6e-34 Identities = 121/369 (32%), Positives = 161/369 (43%), Gaps = 31/369 (8%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHTYAADV 3356 LITGG GA+G A +LA+ G +VLTSRR D A + + E+ + A D Sbjct: 2878 LITGGTGALGGRVARWLARAGVERLVLTSRRGLDAPGAAQLVAELG----VDVSVVACDA 2933 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXX 3414 D + LLA AE L + H AGVLDD +L A PERF + L KA A H Sbjct: 2934 SDRDALRALLA---AEAEGLTAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHEL 2990 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQANYA ANA LD L +RRA GL AT I +GPW + Sbjct: 2991 TGELGIELSAFVLFSSMSGSIGAAGQANYAAANAYLDALAEQRRAAGLAATSIAWGPWAE 3050 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQR-AAKVLGSAR 3533 GGMA+ A A + G+ P+D A+ A + + TV W+R + R Sbjct: 3051 GGMAADGALDARMRRDGVPPMDAQPAIRAFRQAVGAADASLTVADVEWERYLSGHTAVRR 3110 Query: 3534 PPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFL----QREVQNFLRL----- 3584 + + A A D+ AG + RE+ +R Sbjct: 3111 SELFSELTEVRAARAGADARTQPAAHTDGAVTLAGRLAALAPAEQTRELLGLVRTHVAAV 3170 Query: 3585 -----ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEY- 3638 A A F +LG DSL A+ELRNRL + + + T ++DYPT LA++ Sbjct: 3171 LGHDGADAVGAERAFKELGFDSLTAVELRNRLGA--ATELRLPVTLIYDYPTSAALADHL 3228 Query: 3639 ---LVGQLP 3644 LVG +P Sbjct: 3229 REELVGSIP 3237 Score = 134 bits (337), Expect = 3e-28 Identities = 118/370 (31%), Positives = 164/370 (44%), Gaps = 29/370 (7%) Query: 3298 LITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHT--YAA 3354 L+TG G++G A +L GA ++L SRR P +A A + I E + H A Sbjct: 4646 LVTGATGSLGRLFARHLVTAYGAERLLLVSRRGP--AADGADELIAELARLGAHAELVAC 4703 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXX 3414 D+ D+ ++A LLA + AE PL + H AGVLDD +LS+ PER + L PK A + Sbjct: 4704 DIADKGELAALLASVPAE-HPLTAVVHTAGVLDDGVLSSLTPERVASVLRPKVDAAWNLH 4762 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQANYA ANA L+ L +RRA+GL A + +G W Sbjct: 4763 ELTRDLGLSAFVLFSGAAAAFGAAGQANYAAANAFLEALAEQRRAEGLAAVSLAWGLWAP 4822 Query: 3475 ------GGMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSG-------QATVLK 3519 GMAS E I G+ L L + S VL+ Sbjct: 4823 QAGSSGEGMASRLDEVDLRRIARDGVGALGAEEGLGLFDTAMTVDSAVLMPIHLDLAVLR 4882 Query: 3520 ANWQRA----AKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQ 3575 A A A + G R P + G A S L+ +L+ +P+ + G + + + Sbjct: 4883 AQAVSAGSTPALLKGLVRVPARRTLERRTGGGADAGSPLVARLLALPVAEHEGVLLDLVC 4942 Query: 3576 REVQNFLRLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIG 3633 V L A A F DLG DSL A+ELRN L ++ G + T +FDYPT Sbjct: 4943 GRVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKAETG--LRLPPTLIFDYPTPV 5000 Query: 3634 GLAEYLVGQL 3643 LA +L+ +L Sbjct: 5001 ALARHLLAEL 5010 Score = 129 bits (323), Expect = 1e-26 Identities = 116/369 (31%), Positives = 164/369 (44%), Gaps = 28/369 (7%) Query: 3298 LITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHT--YAA 3354 L+TG G +G A +L GA ++L SRR P +A A + I E + H A Sbjct: 7938 LVTGATGGLGRLFARHLVTAYGAERLLLVSRRGP--AADGADELIAELARLGAHAELVAC 7995 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXX 3414 D+ D + LLA + AE PL + H AGVLDD +LS+ P+R + L PK A + Sbjct: 7996 DIADREALGALLASVPAE-HPLTAVVHTAGVLDDGVLSSLTPDRVASVLRPKVDAAWNLH 8054 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQANYA ANA L+ L +RRA+GL A + +G W Sbjct: 8055 ELTRDLDLSAFVLFSGAAAAFGAAGQANYAAANAFLEALAEQRRAEGLPAASLAWGLWAP 8114 Query: 3475 GGMASSEAATANITAQGL--IPLDPSAALHALAEV----IANGSGQATVLKANWQRA--- 3525 +S E A + L I D AL A + A A ++ + A Sbjct: 8115 QTGSSGEGMAARLDEADLRRIARDGVGALGAEEGLGLFDTAMTVDSAVLMPIHLDLAVLR 8174 Query: 3526 AKVLGSARPPILDLVL---PSAAGEATGD------SELLKQLMEIPIPQRAGFVTEFLQR 3576 A+ + + PP L L P+ GD S L +L+ +P+ + G + + + Sbjct: 8175 AQAISAGSPPALLRALVRVPARRTATRGDGGTESGSPLTARLLALPVAEHEGVLLDLVCG 8234 Query: 3577 EVQNFLRLASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGG 3634 V L A A F DLG DSL A+ELRN L ++ G + T +FDYPT Sbjct: 8235 RVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKTETG--LRLPPTLIFDYPTPAA 8292 Query: 3635 LAEYLVGQL 3643 LA +L+ +L Sbjct: 8293 LARHLLSEL 8301 Score = 43.9 bits (102), Expect = 0.48 Identities = 38/115 (33%), Positives = 57/115 (49%), Gaps = 8/115 (6%) Query: 3544 AAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSR--FLDLGTDS 3601 A+G G ++L + ++ + +++ V LR A+P A + FLDLG DS Sbjct: 61 ASGGPDGPDGWRERLAGLTETEQHTTLLDWVSSLVTASLRDAAPTALDPQRSFLDLGFDS 120 Query: 3602 LMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAE----YLVGQLPDAEAPETA 3652 L A++L RL + G + + T FD+PT LA L+G AEAP TA Sbjct: 121 LAAVDLHARLVAGTGLRLPV--TLAFDHPTPAHLARRIHALLLGLTAPAEAPVTA 173 >tr|B6ZIR4|B6ZIR4_STRPT Tax_Id=58346 (pldAIII)SubName: Full=Polyketide synthase;[Streptomyces platensis] Length = 3712 Score = 1607 bits (4161), Expect = 0.0 Identities = 1037/2698 (38%), Positives = 1418/2698 (52%), Gaps = 92/2698 (3%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G A R+PG S EE W L+ G +A+S+ P DR W++EE + PDP G R Sbjct: 38 AIVGMACRYPGGVTSPEELWDLVAGGTDAVSEFPADRGWNVEELYHPDPDHSGTSYVREG 97 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ + FD FFGMS RE DPQ R+L+ETAW A E GI P L S TGVFVG+ Sbjct: 98 GFLHEAAEFDPVFFGMSPREALATDPQQRLLLETAWEAFERGGIDPLRLRGSRTGVFVGV 157 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 +DYL + E + G++ + A GR++Y GL+GPAV VDTACSSSLVA+H Sbjct: 158 MYNDYLTRLQPAPA--DFEGQLGNGSAGSVATGRLAYTFGLEGPAVTVDTACSSSLVALH 215 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC +ALAGG V+ TP FS LA DGRCK F AAADG EG G Sbjct: 216 LAAQALRNGECTMALAGGVAVMATPGPFTEFSRQRGLAVDGRCKPFAAAADGTGWAEGVG 275 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DA R+G + AVIRG+A+NQDGAS GLTVPNG +QQRVI AL AGL AD Sbjct: 276 LLLVERLSDARRNGHPVLAVIRGTAVNQDGASSGLTVPNGPSQQRVIRQALANAGLSAAD 335 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R PL +GS K+NIGH + Sbjct: 336 VDAVEAHGTGTPLGDPIEAQALIATYGQDRPAGRPLWLGSLKSNIGHTQAAAGAAGVMKM 395 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + TLPK L+ + P+P + WE +E++ E VPW +PR AGVSSFG +GTNAH Sbjct: 396 VQAMRHGTLPKSLHIDAPTPQVDWEAGAVELLTEAVPWHETDRPRRAGVSSFGVSGTNAH 455 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQARLAD 490 VI+EEAP P P LP +S R EA+ AG+ R +L + L Sbjct: 456 VIIEEAPPTEAPEGVT-ARAPLNAETLPWVVSGRGVEAVRAQAGQLRSYLSERQDSSLEG 514 Query: 491 VSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQ 550 + + T R+ + RA ++ + + L ALA PA GLV GE+ A +F GQ Sbjct: 515 IGLSLATTRSAFQHRAVVLAADHDGFMAGLDALATGEPAKGLVDGEAVSGGGVALVFPGQ 574 Query: 551 GSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTY 610 GSQ+ GMA EL D+ VF + + CA+A++ ++ L +V+ E L Sbjct: 575 GSQWAGMALELLDSSSVFRDRMEACAQALSPYIDWSLTEVLRSC-------EGELERVDV 627 Query: 611 AQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFG 670 QPAL+AV + LA LW+S+G P V+GHS G+ +AACVAG +ED A ++A R + Sbjct: 628 VQPALWAVMVSLAELWRSFGVRPAAVLGHSQGEIAAACVAGALSLEDAALVVALRSQAIA 687 Query: 671 SLPAG-GRMAAVFTAPERAER-LTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLVAD 727 + AG G M +V RA+ +T LSVAA NG + V+SG +E A L A+ Sbjct: 688 TELAGRGAMLSVALPKARAQDWMTGRAERLSVAAVNGPGSVVVSGDVDAVEELRAELAAE 747 Query: 728 GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAY 787 GVR L +A HS+ ++ I + + R + L + TG + +T +D Y Sbjct: 748 GVRVRRLPVDYASHSSHVERIRTRLLAALAPVSPRPSEITLYSSVTGGPIDTTT-MDAEY 806 Query: 788 WRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTT 847 W R+ RQ VEF ++VRT R +E P PVLT D + SLR + Sbjct: 807 WYRNLRQTVEFERAVRTSMSDGYRFFIESSPHPVLTTGIEETAEDADRFAAAVGSLRRSD 866 Query: 848 ADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQT 906 + A+A A+ G ++ F + DLPTY F+ +++W + + + D Sbjct: 867 GGPDRFLTALAEAHVRGVPVEWAVMFAGRPVSQPDLPTYSFQRQRYWLAPDTSPGDD--- 923 Query: 907 ASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTL--RVLNKLAARHNQQRSTHVD 964 G T+ +E + EL+ + D Q +L L Q RS V Sbjct: 924 --GGGDERSETRFWEAVERQDLGELSETLRIGDADRQASLGELLPALWTWREQNRSAAVL 981 Query: 965 PDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDAD 1024 RY + W W++V A ++A+AL+ D Sbjct: 982 DSWRYRVSW-RPVSPASDPALPGTWLIVVPAGTADQQWAEALSRAAE---------GLGD 1031 Query: 1025 EAQLVDTLRAASAGELYVVHIA--AGDGAAAPMRDLLRVQHRT----------LGGLRRL 1072 +A V+ RA + E Y +A A G A + LL + + L Sbjct: 1032 QAVRVELGRAEAGREEYAARLAEAAAGGPVAGVLSLLALAEEPADADPVWRPYVTSTLAL 1091 Query: 1073 FRAANDAELRSPIWLVTRDGQRVTDTDTVVPE---QSCLWGFGRAAALELPHIWGGLADL 1129 +A DA + +P+WL TR + +D VP Q+ LWG GR LE P WGGL DL Sbjct: 1092 MQALGDAGIGAPLWLATRGAVSIGRSDKPVPSTAAQAQLWGLGRVMGLEHPERWGGLVDL 1151 Query: 1130 SGADTEWPRLIARITSPRDG----EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTY 1185 +T R AR+ G EDQ A+R VY RLVR + RT Sbjct: 1152 P--ETADARATARLAGILAGGLGPEDQCAVRSSGVYVRRLVRAPLDRRARRPSWHTSRTA 1209 Query: 1186 LVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVA 1245 LVTGG G +G VA +LAS GA H+VLTSRR P V V+ DV+ Sbjct: 1210 LVTGGTGGLGAHVARWLASTGAEHLVLTSRRGPDAPGTDELCAELSALGVRVSVVACDVS 1269 Query: 1246 DAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEAL 1305 D +A + + A+ + +VHAAG L+ L AE AGK GA HL E L Sbjct: 1270 DRDQLAATLARLTADGHTVRTVVHAAGVSTPGALADLGPAEFAEAVAGKAAGAAHLDELL 1329 Query: 1306 TDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG 1365 D +LD FV SS A VWGG GQ AY AANA+LD LA R R RG A SV +G WA G Sbjct: 1330 GD--AELDAFVLFSSNAGVWGGGGQGAYAAANAYLDALAKRRRSRGRVATSVAWGAWAGG 1387 Query: 1366 MADAESRA--RLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQAGRR 1422 AE A +L +RGVR + PA A++ + + + + VA +DW RFLP + A R Sbjct: 1388 GMAAERTADEQLRRRGVRAMDPAMAISALQEALEHEETFLAVADMDWDRFLPSFTMARPR 1447 Query: 1423 AFLSEL-ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR-NAVAEVTR 1480 L +L E + L +QL +R + + +R +A A + Sbjct: 1448 PLLDDLPEVQRQRLSAAPSWATAETDGPALAQQLAGVFEPERGRRLLDLVRKHAAAVLGY 1507 Query: 1481 VDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVL 1540 +E+ E F +LG DSL AVE+R R++ G +P TLV DHP A +L E+ Sbjct: 1508 AGPNEVEAERAFRELGFDSLTAVEMRNRLQPATGLTLPATLVFDHPTPRALAAHLRDELF 1567 Query: 1541 GLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR- 1598 G+ + T + + +A DDPIA+V++ CRFPG PE WELL G DA+ P DR Sbjct: 1568 GVQDDTP--EPARASAPDDDPIAIVSMGCRFPGGVSSPEGLWELLLSGRDAMSSFPVDRG 1625 Query: 1599 WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEG 1658 WD+D P G YT FGISPREA+ ++PQQRL+LE WE Sbjct: 1626 WDLDSLAGDGPGQIGGGYTLEGGFLDDAAGFDAALFGISPREALAMDPQQRLLLEASWEA 1685 Query: 1659 LERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFAL 1718 ERAG +DLR SRTGVF G ++ YA + +AES + +E H +TG+A + +SGR+++ Sbjct: 1686 FERAGIPSADLRSSRTGVFIGASSQGYAQV-AAESAEGVEGHVVTGDAASVMSGRLSYTF 1744 Query: 1719 GFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSP 1778 G EGPAV VDTACSS+LVA+H A QAL++G+C LALAGGV V+++P V SR R L+ Sbjct: 1745 GLEGPAVTVDTACSSSLVALHLAAQALRNGECTLALAGGVAVMVTPAAFVEFSRQRGLAA 1804 Query: 1779 VGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPN 1838 GRCK F +ADG EG GVL+++RLSDA R+G V AV+ S+VNQDGAS+GLT PN Sbjct: 1805 DGRCKAFADAADGTGWGEGVGVLLVERLSDARRNGHPVLAVVSGSAVNQDGASNGLTAPN 1864 Query: 1839 GGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMG 1898 G +QQR+I+ LA AGL+GADVD +EAHGTGT LGDPIE Q PL +G Sbjct: 1865 GPSQQRVIQQALANAGLAGADVDAVEAHGTGTRLGDPIEAQALIATYGQARSADRPLWLG 1924 Query: 1899 SVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQ 1958 S+K+NIGHT++A+G AG+IK++ ++ HG LP++LH + PS + W+A V ++ E +PW Sbjct: 1925 SLKSNIGHTQAAAGVAGVIKMIQAMGHGTLPRTLHVDRPSSQVDWEAGAVELLTEAMPWP 1984 Query: 1959 TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSA 2018 R RRA VSSFG +GTNAHV++E AP D P LSA Sbjct: 1985 EADRPRRAAVSSFGVSGTNAHVIIEHAPQVTPASQAPEPVKSPDAVEA--DRPVPWLLSA 2042 Query: 2019 RSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXX 2078 S AL E+A R + + P + A+V + RS RAA+V Sbjct: 2043 GSDAALGEVAERLAAYAESHPEVSAAEVAFSLATTRSLLPCRAAVVGADRDELVQRIRSV 2102 Query: 2079 XXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADML 2138 T GV G TTA+LF+GQGSQ GM EL+ P FA+ + + + Sbjct: 2103 GGGTTAPGVFCGTASSECTTAFLFSGQGSQRLGMGHELYAAHPEFAEALDEVCGHLDVFG 2162 Query: 2139 PRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYA 2197 RPL +VLFA D A L+ FAQPALFA+E+ L R ++W I PD + GHS+G+ A Sbjct: 2163 DRPLKEVLFAQADGADAGLIDGAGFAQPALFALEVALYRTLEAWGITPDYLAGHSLGEIA 2222 Query: 2198 AACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAG---EFPRVSVGA 2254 AA VAGVFSL+D ARL+ RG++ +LP GG MVAV A + + ++ E V + A Sbjct: 2223 AAHVAGVFSLEDAARLVTARGQLMQALPGGGAMVAVQASEDEILAISAPWLEGDGVGIAA 2282 Query: 2255 YNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXX 2313 NGP + V+SG E + I + +G + L+ SHAFHS +DP+LD Sbjct: 2283 VNGPASVVVSGDEEAVLAIAGHWRAQGRKTRRLSVSHAFHSPHMDPMLDGFRRVVDGMHL 2342 Query: 2314 XXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPV 2373 P +P++ N TG + A YW RH RQ V+F + ++T+ G + +EIGP Sbjct: 2343 VEPVIPVISNLTGRLADPGQLTSADYWVRHVRQAVRFHDGLQTLHDQGVTTYLEIGPDAQ 2402 Query: 2374 LTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAA-VHRQPRRPV 2432 LT A + V++LR+ + + LA + G PD+ ++ +P P Sbjct: 2403 LTAMAQEALSPQ---SHTVSTLRRNQPETTSLLTTLARLHTTGTTPDWITYLNHRPSSPT 2459 Query: 2433 ELPTYPFQRRRFWPKASSIAVDGGTAA-SG----ILGSGKDLASGD-TIYTSRLSVKSQP 2486 LPTYPFQ R+WP+ + A D +A SG +LG+ LA GD ++T RLS ++ Sbjct: 2460 PLPTYPFQHHRYWPRGDAQAADVSSAGLSGANHPLLGAAVPLADGDGHLFTGRLSARTHR 2519 Query: 2487 WLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHP 2543 WLADH + G VV+PG + +A+ A VG ++++++ P++LPE + +VQL L Sbjct: 2520 WLADHQVGGNVVLPGTAFVELAVRAGDQVGC-SQVEELTLEAPLVLPESGAVQVQLRLGR 2578 Query: 2544 ADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMR 2603 AD ++ R G G D L E T +G A+A E E + Sbjct: 2579 ADESGRRDLTVYGRLAG-GGEDLWLEEEWTRHASGVLSSASAPEPVALTVWPPSAAEAVP 2637 Query: 2604 PQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMD 2661 + + A+ +GP + G L++ W ++ + + E+ S +HP L+D Sbjct: 2638 VEGFYTGLAESGYGYGPAFQG-LRAAWRQGDTVFAEVQLPEVVREEAASYTIHPALLD 2694 Score = 635 bits (1639), Expect = e-179 Identities = 376/903 (41%), Positives = 516/903 (57%), Gaps = 19/903 (2%) Query: 1560 DPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYT 1617 +P+A+V ++CR+P G PE W+L+AGG DA+ E P DR W+++E Y PDPD G +Y Sbjct: 35 EPVAIVGMACRYPGGVTSPEELWDLVAGGTDAVSEFPADRGWNVEELYHPDPDHSGTSYV 94 Query: 1618 RXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVF 1677 R P FFG+SPREA+ +PQQRL+LET WE ER G P LRGSRTGVF Sbjct: 95 REGGFLHEAAEFDPVFFGMSPREALATDPQQRLLLETAWEAFERGGIDPLRLRGSRTGVF 154 Query: 1678 TGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVA 1737 GV N+Y L D E G+A + +GR+A+ G EGPAV VDTACSS+LVA Sbjct: 155 VGVMYNDYLTRLQPAPAD-FEGQLGNGSAGSVATGRLAYTFGLEGPAVTVDTACSSSLVA 213 Query: 1738 VHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEG 1797 +H A QAL++G+C +ALAGGV V+ +P SR R L+ GRCK F A+ADG +EG Sbjct: 214 LHLAAQALRNGECTMALAGGVAVMATPGPFTEFSRQRGLAVDGRCKPFAAAADGTGWAEG 273 Query: 1798 CGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSG 1857 G+L+++RLSDA R+G V AVI ++VNQDGASSGLTVPNG +QQR+I LA AGLS Sbjct: 274 VGLLLVERLSDARRNGHPVLAVIRGTAVNQDGASSGLTVPNGPSQQRVIRQALANAGLSA 333 Query: 1858 ADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLI 1917 ADVD +EAHGTGTPLGDPIE Q PL +GS+K+NIGHT++A+GAAG++ Sbjct: 334 ADVDAVEAHGTGTPLGDPIEAQALIATYGQDRPAGRPLWLGSLKSNIGHTQAAAGAAGVM 393 Query: 1918 KVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTN 1977 K+V +++HG LP+SLH + P+P + W+A V ++ E VPW R RRAGVSSFG +GTN Sbjct: 394 KMVQAMRHGTLPKSLHIDAPTPQVDWEAGAVELLTEAVPWHETDRPRRAGVSSFGVSGTN 453 Query: 1978 AHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSA 2037 AHV++EEAPP + P V +S R EA+ A + +LS Sbjct: 454 AHVIIEEAPP-----TEAPEGVTARAPLNAETLPWV--VSGRGVEAVRAQAGQLRSYLSE 506 Query: 2038 TPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPT 2097 + + + RS F++RA ++ G+V GE V Sbjct: 507 RQDSSLEGIGLSLATTRSAFQHRAVVLAADHDGFMAGLDALATGEPAKGLVDGEAVSGGG 566 Query: 2098 TAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLL 2157 A +F GQGSQ+ GMA EL D+ VF + CA+A++ + L +VL + + E L Sbjct: 567 VALVFPGQGSQWAGMALELLDSSSVFRDRMEACAQALSPYIDWSLTEVLRSCEGE----L 622 Query: 2158 QHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAER 2217 + QPAL+AV + LA LW+S+ + P VLGHS G+ AAACVAG SL+D A ++A R Sbjct: 623 ERVDVVQPALWAVMVSLAELWRSFGVRPAAVLGHSQGEIAAACVAGALSLEDAALVVALR 682 Query: 2218 GRMFGS-LPEGGRMVAV-FADAEHVEQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVE 2274 + + L G M++V A + + G R+SV A NGP + V+SG + +EE+ Sbjct: 683 SQAIATELAGRGAMLSVALPKARAQDWMTGRAERLSVAAVNGPGSVVVSGDVDAVEELRA 742 Query: 2275 RFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTP 2334 EG+R L +A HS ++ + + L + TG + T Sbjct: 743 ELAAEGVRVRRLPVDYASHSSHVERIRTRLLAALAPVSPRPSEITLYSSVTGGPI-DTTT 801 Query: 2335 LDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVAS 2394 +DA+YW R+ RQ V+F +VRT + G +E P PVLT + + AV S Sbjct: 802 MDAEYWYRNLRQTVEFERAVRTSMSDGYRFFIESSPHPVLTTGIEETAEDADRFAAAVGS 861 Query: 2395 LRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSIAV 2453 LR+ + ALA A+V G ++A + +P +LPTY FQR+R+W + Sbjct: 862 LRRSDGGPDRFLTALAEAHVRGVPVEWAVMFAGRPVSQPDLPTYSFQRQRYWLAPDTSPG 921 Query: 2454 DGG 2456 D G Sbjct: 922 DDG 924 Score = 330 bits (845), Expect = 3e-87 Identities = 273/807 (33%), Positives = 382/807 (47%), Gaps = 61/807 (7%) Query: 2873 LWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXX 2931 L +VT VA +GE + D AA+ G ++ +E P LVD DG++E+ Sbjct: 2862 LAVVTRGAVAVGAGEVLADAAGAAVTGLVKSAESENPGRFL-LVDVDGTTES---WRALP 2917 Query: 2932 XXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGD--FVLAPTERGAIDNLRLTETD 2989 G EP+IA+R G+ RL+ G LP G + L E G++D LRL + Sbjct: 2918 TLGGGDEPQIALRDGQAYVPRLVRAGEDGGSLLPPAGADAWRLETGEAGSLDGLRLAPAE 2977 Query: 2990 VPEPD--EGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIG 3047 + G V++ V AAGLNFRDVL LG+YPG +G + AG V + G GV+GL +G Sbjct: 2978 DAQAALLPGQVRIAVRAAGLNFRDVLGALGMYPGGLDLLGSEIAGEVLETGDGVTGLAVG 3037 Query: 3048 QRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKV 3106 RV G + G F + + IP G AA +P A LT + L G +V Sbjct: 3038 DRVMGLVAGGFGPMAVADSWRVVRIPSGWTFTRAAGVPVAFLTALYGLRELGGLAAGQRV 3097 Query: 3107 LIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLGV--KYVYDSRTTDFADQILA 3164 L+HAA+GGVG AA+Q+A+ GAEV+ATAS K+ + LGV + SRT DFA Sbjct: 3098 LVHAAAGGVGTAAVQLARLLGAEVYATASAPKQEYVADLGVDRARIASSRTLDFASSF-- 3155 Query: 3165 DTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVA 3224 VDVVLNSL + +V+A+L +GGRF E+ K D+ R AY+ V Sbjct: 3156 ----PEVDVVLNSL-AGEYVDASLGLLREGGRFVEMGKTDV---------RDAAAYDGVT 3201 Query: 3225 LDTVMFTE--PDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIX 3282 T + P+ I +L E+ + GE TP+ + + A AFR M QARH GKI Sbjct: 3202 YRTFDLGQAGPELIARMLGELVEWFEAGELTPVRTAAWDVRRAVGAFRWMSQARHTGKI- 3260 Query: 3283 XXXXXXXXXXXDRSYLITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEI 3341 D + LITGG G +G A +L + G ++L SR + +R ++E+ Sbjct: 3261 -VLTVPRDLDADGTVLITGGTGTLGGLLARHLVTEHGVRHLLLVSRTGERAALRRELEEL 3319 Query: 3342 TERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRT 3401 + A D+ D A VA+LL I +E PL G+ H AGVLDD +++ + R Sbjct: 3320 ----GAEVRIAACDMADRAAVAELLDGIPSE-HPLTGVFHAAGVLDDGVVTGLDSARLAR 3374 Query: 3402 TLAPKAYGASHXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQG 3461 LAPK GA H GQA YA AN LD L +RRAQG Sbjct: 3375 VLAPKVDGALHLHELTAELDLSAFVLFSSMSGLLGASGQAGYAAANMFLDALAQQRRAQG 3434 Query: 3462 LVATGINFGPWGQGGMASSEAATANITAQ---GLIPLDPSAALHALAEVIANGSGQATVL 3518 L A + +G W ++ + ++ G++ L + + L A SG+A ++ Sbjct: 3435 LPALSLAWGLWETASAMTAHLSDTDLRRMGGIGMLGLTRNEGMELLD--AAWQSGEALLV 3492 Query: 3519 KANWQRAA---KVLGSARPPIL---------DLVLPSAAGEATGDSELLKQLMEIPIPQR 3566 W + AR P L +P +A A G L ++L +P +R Sbjct: 3493 PVRWDHRVLRERASSGARVPSLLRRLVRAPRRRTVPESAKGAGGG--LRERLATLPEAER 3550 Query: 3567 AGFVTEFLQREVQNFLRLASPPAAS--SRFLDLGTDSLMAIELRNRLHSQFGGKFTINAT 3624 G + E + V L A A S F +LG DSL ++E RNRL+ G + +T Sbjct: 3551 RGMLIELVAGHVAAVLGHAGTDAVSVDRPFKELGFDSLTSVEFRNRLNEATG--LRLPST 3608 Query: 3625 AVFDYPTIGGLAEYLVGQLPDAEAPET 3651 VFD+PT LA L LP AE T Sbjct: 3609 LVFDHPTPTTLAARLDALLPGAETATT 3635 Score = 176 bits (445), Expect = 8e-41 Identities = 122/362 (33%), Positives = 168/362 (46%), Gaps = 15/362 (4%) Query: 3295 RSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAA 3354 R+ L+TGG G +G H A +LA GA +VLTSRR PD + R+ A Sbjct: 1207 RTALVTGGTGGLGAHVARWLASTGAEHLVLTSRRGPDAPGTDELCAELSALGVRVSVVAC 1266 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXX 3414 DV D Q+A LAR+ A+ + + H AGV L+ P F +A KA GA+H Sbjct: 1267 DVSDRDQLAATLARLTADGHTVRTVVHAAGVSTPGALADLGPAEFAEAVAGKAAGAAHLD 1326 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQ YA ANA LD L +RR++G VAT + +G W Sbjct: 1327 ELLGDAELDAFVLFSSNAGVWGGGGQGAYAAANAYLDALAKRRRSRGRVATSVAWGAWAG 1386 Query: 3475 GGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 GGMA+ A + +G+ +DP+ A+ AL E + + V +W R ARP Sbjct: 1387 GGMAAERTADEQLRRRGVRAMDPAMAISALQEALEHEETFLAVADMDWDRFLPSFTMARP 1446 Query: 3535 -PILD----------LVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLR 3583 P+LD PS A T L +QL + P+R + + +++ L Sbjct: 1447 RPLLDDLPEVQRQRLSAAPSWATAETDGPALAQQLAGVFEPERGRRLLDLVRKHAAAVLG 1506 Query: 3584 LASP--PAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 A P A F +LG DSL A+E+RNRL G T+ AT VFD+PT LA +L Sbjct: 1507 YAGPNEVEAERAFRELGFDSLTAVEMRNRLQPATG--LTLPATLVFDHPTPRALAAHLRD 1564 Query: 3642 QL 3643 +L Sbjct: 1565 EL 1566 Score = 147 bits (372), Expect = 2e-32 Identities = 129/416 (31%), Positives = 195/416 (46%), Gaps = 29/416 (6%) Query: 1167 RRTGEPSDT-PLPVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXX 1224 R TG+ T P + D T L+TGG G +G +A +L + HG H++L SR Sbjct: 3255 RHTGKIVLTVPRDLDADGTVLITGGTGTLGGLLARHLVTEHGVRHLLLVSRT----GERA 3310 Query: 1225 XXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDD 1284 E+ +VR+ D+AD VA L+ + +E PL G+ HAAG + ++GLD Sbjct: 3311 ALRRELEELGAEVRIAACDMADRAAVAELLDGIPSE-HPLTGVFHAAGVLDDGVVTGLDS 3369 Query: 1285 AEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLA 1344 A + RV A KV GA HL E +L DL FV SS++ + G GQ Y AAN FLD LA Sbjct: 3370 ARLARVLAPKVDGALHLHELTAEL--DLSAFVLFSSMSGLLGASGQAGYAAANMFLDALA 3427 Query: 1345 WRLRERGVTAVSVNFGPW------AAGMADAESRARLEQRGVRTLSPAEALAGMADVVAG 1398 + R +G+ A+S+ +G W A ++D + R R+ G+ L+ E + + D Sbjct: 3428 QQRRAQGLPALSLAWGLWETASAMTAHLSDTDLR-RMGGIGMLGLTRNEGME-LLDAAWQ 3485 Query: 1399 PVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKA 1458 + ++ + W + + + S L + L E+L Sbjct: 3486 SGEALLVPVRWDHRVLRERASSGARVPSLLRRLVRAPRRRTVPESAKGAGGGLRERLATL 3545 Query: 1459 PVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDI 1517 P +R+ ++ + VA V D + + F +LG DSL +VE R R+ + G + Sbjct: 3546 PEAERRGMLIELVAGHVAAVLGHAGTDAVSVDRPFKELGFDSLTSVEFRNRLNEATGLRL 3605 Query: 1518 PVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTD-----DPIAVVAVS 1568 P TLV DHP + A L + L G +T A+TV A T D +A V +S Sbjct: 3606 PSTLVFDHPTPTTLAARL--DALLPGAET----ATTVAAPTSPHEELDRLATVLLS 3655 >tr|Q82QT4|Q82QT4_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 7746 Score = 1604 bits (4153), Expect = 0.0 Identities = 1083/2863 (37%), Positives = 1466/2863 (51%), Gaps = 172/2863 (6%) Query: 9 EPTPSFAIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGK 66 +P AI+ + R PG S+ E+ W LL G + IS P DR WD+E +DP+P TPGK Sbjct: 1043 DPHEPIAIVAMSCRLPGGVSSPEDLWRLLASGGDGISGFPTDRGWDVETLYDPEPGTPGK 1102 Query: 67 VVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNT 126 TR GF+ + FDA FFG+S RE +DPQ R+++ETAW A E +GI P +L S Sbjct: 1103 SSTRHGGFLHEAAEFDAGFFGISPREAAAIDPQQRLVLETAWEAFERAGIDPATLRGSRA 1162 Query: 127 GVFVGLATHDYLGMASDELTYPE--IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTAC 184 GVF+G DY L P +E Y+ GT+ + A+GR++Y GL+GPAV VDTAC Sbjct: 1163 GVFIGATAQDY----GPRLHEPADGVEGYLLTGTTTSVASGRVAYSFGLEGPAVTVDTAC 1218 Query: 185 SSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADG 244 SSSLVA+H A Q+LR EC +ALAGG V+ TP + FS L+ DGRCK F A ADG Sbjct: 1219 SSSLVALHLAVQSLRSGECTMALAGGVTVMSTPGMFVEFSRQRGLSADGRCKAFAAGADG 1278 Query: 245 YVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALK 304 EG G+++V+RL DA R+G ++ AV+RGSA+NQDGAS GLT PNG +QQRV+ AL Sbjct: 1279 TGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRQALA 1338 Query: 305 RAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXX 364 AGL PADV +EAHGTGT LGDPIEA+A G GR + PL +GS K+NIGH + Sbjct: 1339 AAGLAPADVDAVEAHGTGTLLGDPIEAEALIAAYGQGRDGDRPLWLGSLKSNIGHTQAAA 1398 Query: 365 XXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSF 424 + + LP+ L+ + P+PH+ W + ++ E V W PR A VSSF Sbjct: 1399 GVAGVIKMVMAMRHGVLPRTLHVDEPTPHVDWSASGVRLLTEAVEWPARDLPRRAAVSSF 1458 Query: 425 GFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAH- 483 G +GTNAHVI+E+A PA V P + V SA++ AL AG +L A Sbjct: 1459 GISGTNAHVIVEQAATSEEPARGTAVAGPVPWVV---SAKSDVALREQAGRLLSFLDAEG 1515 Query: 484 ---PQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDR----PAPGLVRGE 536 R DV+ + T+RA LE+RAA+V + L ALA P G V G Sbjct: 1516 VGGAGVRPEDVALSLATSRAVLERRAAVVGGDLAELRQGLEALASGASGAAPVGGAVGG- 1574 Query: 537 SHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADE 596 + +LF+GQGSQ GM REL+ PVFA + V L+ P+ Sbjct: 1575 -----RVGFLFSGQGSQRIGMGRELYAAYPVFAAAY----DEVCAFLDAPV--------- 1616 Query: 597 LDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVE 656 D D+E L T QPALFAVE+ L RL +SWG PD V GHSVG+ +AA VAGV +E Sbjct: 1617 -DVDSEE-LNQTGTTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLSLE 1674 Query: 657 DGARLIAERGRLFGSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGANTVLSGPAK 715 D A+L++ R L +LP GG M AV T E LTD + +AA NG +V+ A+ Sbjct: 1675 DAAKLVSARAALMQALPDGGAMVAVQATEDEVLRHLTD---GVGIAAVNGPRSVVVSGAE 1731 Query: 716 DLESAVATLVAD-GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTG 774 D +AV + A G + L SHAFHS L+DP+L++F + + L + E + ++ N TG Sbjct: 1732 DAVTAVGEIFAGRGRKTSRLKVSHAFHSPLMDPMLEEFAAVVRGLTFSESRIPVVSNLTG 1791 Query: 775 SALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPA 834 T YW RH R+ V FA + TL ++ +E+GP VL+A A + D Sbjct: 1792 RLAEVYTP---EYWVRHVREAVRFADGIETLGELGVTTFVEVGPGGVLSALAQGCFDD-G 1847 Query: 835 TTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWF 894 T + LR + + A+ + G PD++ P AR++DLPTY F+ ++W Sbjct: 1848 TDIVTVPVLRADRPEPYALVTAIGRLHTHGISPDWQVLF-PGARRVDLPTYAFQRERYWL 1906 Query: 895 SDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAAR 954 RA A+AG+ + +E L AL+ E + V +KL+A Sbjct: 1907 DAPRA-------ATAGAPDAMDAEFWDSVESEDRASLGALLGLEPTELDV--VASKLSAW 1957 Query: 955 HNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQ 1014 ++R RY I W +V ++TA + +A+ AG Sbjct: 1958 RRKRREQSTTDGWRYRITWQPLDDMVRAAPSGTWLYVVSEETA----WTEAIRAGLTELG 2013 Query: 1015 IVALP---GSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRR 1071 + +P G D D L A + + AA G A L L Sbjct: 2014 VALVPFAVGEDTDRDALARAFADAGQEQADGILFAAAQGEAGA---------NALQRLVL 2064 Query: 1072 LFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLS 1130 L +A DA + +P+W +T D + P + LWG GR ALE P WGGL DL Sbjct: 2065 LVQALGDAGIEAPLWCLTSGAVSTGTADLLTDPVSAQLWGLGRIVALEQPQRWGGLVDLP 2124 Query: 1131 GA-DTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRR--TGEPSDTPLPVREDRTYLV 1187 D+ +A + + D EDQ+A+R VY RLVR + P+D P R T LV Sbjct: 2125 AELDSRALERLAGLLAQAD-EDQLAVRASGVYGRRLVRAPLSAAPADAPWSPRG--TVLV 2181 Query: 1188 TGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADA 1247 TGG GA+G +VA +LA GA H+VLTSRR P E+ V V+ D AD Sbjct: 2182 TGGTGALGGQVARWLAGAGAEHLVLTSRRGPDAPGAAELKAELEELGAQVTVVACDAADR 2241 Query: 1248 HDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTD 1307 +A L +VH AG + + L ++ V KV A HL E D Sbjct: 2242 DALAELFGRYIVN-----AVVHTAGVLDDGLVESLTPERLNHVLRPKVDAALHLHELTRD 2296 Query: 1308 LRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-AGM 1366 R DLD FV SS+ VWG GQ AYGAANAFLD LA R +GV A++V +G WA GM Sbjct: 2297 -RQDLDAFVLFSSMTGVWGNGGQGAYGAANAFLDALAEHRRAQGVPALAVAWGSWADGGM 2355 Query: 1367 ADAESRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRA-- 1423 AD + L +RGVR ++ A++ + + G VA +DW RF+P + G R Sbjct: 2356 ADGAAGDHLRRRGVRAIAALPAISVLHGALTHGETSMTVADVDWERFVPAF--VGTRPCP 2413 Query: 1424 -FLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RV 1481 L E+ LV++L A ++ ++ + +R A V Sbjct: 2414 LLLGVPEAREALEARARAAQSPEVPVSALVQRLLGATPGEQGRILLDLVREQAATVLGHT 2473 Query: 1482 DADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLG 1541 + F + G DSL AVELR R+ G +P TLV DHP + A +L E+LG Sbjct: 2474 GKGAFEADRTFRETGFDSLTAVELRHRLNTATGLRLPTTLVFDHPTPTALARHLGEELLG 2533 Query: 1542 L-GEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR- 1598 G +T QA T A D+P+A+V +SCR PG PE WELL+ G DA+ P DR Sbjct: 2534 RHGLETAAAQA-TAAAAADEPLAIVGMSCRLPGGVQSPEDLWELLSSGRDAMSGFPTDRG 2592 Query: 1599 WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEG 1658 WDID YDPDPD PGKTY+R FGISPREA+ ++PQQRL+LET WE Sbjct: 2593 WDIDALYDPDPDRPGKTYSREGGFIQGADRFDAGLFGISPREALAMDPQQRLLLETAWEA 2652 Query: 1659 LERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFAL 1718 ERAG A + +R SRTGVF G +YA+ L + ++IE + +TG A + +SGR+++ Sbjct: 2653 FERAGIALASVRASRTGVFIGTNGQDYANGLR-NAPEEIEGYALTGKAASVVSGRISYTF 2711 Query: 1719 GFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSP 1778 G EGPAV VDTACSS+LVA+H A QAL+SG+C +AL GGV V+ +P V SR R LSP Sbjct: 2712 GLEGPAVTVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMTTPDLFVEFSRQRGLSP 2771 Query: 1779 VGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPN 1838 GRCK F A ADG EG G+L+++RLSDA R+G +V A++ S+VNQDGAS+GLT PN Sbjct: 2772 DGRCKAFAAGADGTGWGEGVGLLLVERLSDARRNGHQVLALVRGSAVNQDGASNGLTAPN 2831 Query: 1839 GGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMG 1898 G +QQR+I LA AGL+ ADVD +EAHGTGT LGDPIE Q P+ +G Sbjct: 2832 GPSQQRVIRQALASAGLTPADVDAVEAHGTGTRLGDPIEAQALLATYGQEHSDDRPVWLG 2891 Query: 1899 SVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQ 1958 SVK+NIGHT++A+G AG+IK+VL+++HGVLPQ+LH + P+ H+ W A VR++ EPV W Sbjct: 2892 SVKSNIGHTQAAAGVAGVIKMVLAMRHGVLPQTLHVDEPTAHVDWSAGAVRLLTEPVQWP 2951 Query: 1959 TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSA 2018 RRA VSSFG GTNAH ++EEAP P LSA Sbjct: 2952 GTTGPRRAAVSSFGIGGTNAHTIIEEAPAAAAAEPAREHRPV----------PVPWVLSA 3001 Query: 2019 RSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXX 2078 +S AL A R AT + D ++ RS E+RAA++ Sbjct: 3002 KSEVALRAQAERL--LAFATDDVSPVDAGFSSATTRSALEHRAAVIGSDPAELRAGLEAL 3059 Query: 2079 XXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAEAVADM 2137 A VV G +LF+GQGSQ GM REL+ PVFA + CA Sbjct: 3060 AAGEPAANVVAGRAHSADKVGFLFSGQGSQRLGMGRELYAAYPVFAAAYDEVCA------ 3113 Query: 2138 LPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYA 2197 LLD D ET L T QPALFAVE+ L RL +SW I PD V GHSVG+ A Sbjct: 3114 ----LLDATVDVDAET---LHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIA 3166 Query: 2198 AACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNG 2257 AA VAGV SL+D A+L++ R + +LP GG MVAV A E + R + A NG Sbjct: 3167 AAHVAGVLSLEDAAKLVSARAALMKALPAGGVMVAV--QAAEDEMLPHLIDRAGIAAING 3224 Query: 2258 P-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXP 2316 P + V+SG + + I E F +G + + L SHAFHS L+DP+L+ P Sbjct: 3225 PRSVVISGAEDAVTAIAEVFAAQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSEP 3284 Query: 2317 TLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG 2376 +P+V N TG + TP +YW RH R+ V+FA+ V T+ LG + +EIGP VL+ Sbjct: 3285 WIPVVSNLTGRLTESYTP---EYWVRHVREAVRFADGVLTLHELGVTTFVEIGPGGVLS- 3340 Query: 2377 AAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPT 2436 A VQ + + +LR + + + A A +V G D+ A RR VELPT Sbjct: 3341 ALVQGCLDDGTDIVTIPALRADRPEPQALTTAYAQLHVSGAEVDWHAFFPGARR-VELPT 3399 Query: 2437 YPFQRRRFWPKASSI-----AVDGGTAASGILGSGKDLA-SGDTIYTSRLSVKSQPWLAD 2490 Y FQR R+W A + AV G A +LG+ LA S + T RLS + PWL D Sbjct: 3400 YAFQRERYWLDAPASAGDMRAVGQGEAGHPLLGAAVPLADSVGHLLTGRLSKHTHPWLVD 3459 Query: 2491 HVIYGTVVVPGATYAAMALAAVGTPA--RLKDVFFYEPIILPEKASREVQLTLHPADGGS 2548 H + G ++PG + +A+ A L+++ P+++PE+ +Q+ + DG Sbjct: 3460 HAVSGVALLPGTAFVELAITAADAVGCDLLEELTLETPLLVPERGGVALQVHVGADDGSG 3519 Query: 2549 VLSFQIHSR-PYGERGAD-------WSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLE 2600 +HS+ G+ A W +A G + A P + PV E Sbjct: 3520 RRPLTVHSQIDDGDAYAHEDDSERAWVRHASGVLTVATGGPVDGSLTAWPPVG-----AE 3574 Query: 2601 RMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI-LVGAELAEQLGSEPMHPVL 2659 + ++ A + L +GP + G L++ W + ++ L GAE + G+ +HP L Sbjct: 3575 PVDVDGFYDRLAGMALDYGPVFQG-LRAAWRSGDDFFAEVELPGAERTD-AGAYGLHPAL 3632 Query: 2660 MDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQ 2719 D E G + LP + V LA + S + T Sbjct: 3633 FD---AALHTVWLGAVEPEAGTGNGLLPFAWSGVRLAAAGASDLRVKV----SRAGTGTS 3685 Query: 2720 VFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAV 2779 L D G + + T++ P + L G G D ++ L W V P + D Sbjct: 3686 TVSLVLADGTGGPVAEVDSLTLRPVPADQLRAGSGSDDA--VFGLKWTPVSLPSAPDG-- 3741 Query: 2780 GTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAG 2822 I +++LAA P D D + + G G Sbjct: 3742 --MRIETYEDLAALRATDPPADTEADAAAAADAVVVPCPTGTG 3782 Score = 866 bits (2237), Expect = 0.0 Identities = 673/1983 (33%), Positives = 952/1983 (48%), Gaps = 180/1983 (9%) Query: 1030 DTLRAASAG-ELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLV 1088 D LR + ++ VV AG G R+ H T + L + E + LV Sbjct: 5468 DALRESEGTPDVVVVPCPAGSG-----RETADRVHSTTSEVLALVQWWLAEERAGRLALV 5522 Query: 1089 TRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRD 1148 TR G + +WG R+A E P L + D L A + S Sbjct: 5523 TRPGDLA---------HAAVWGLVRSAQSENPDRIV-LVEAEETDEAVRVLPAALAS--- 5569 Query: 1149 GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT--YLVTGGLGAIGLEVAGYL-ASH 1205 GE Q A+R V+ PRLV+ T + T + L+TG GA+G VA +L A H Sbjct: 5570 GEPQFAVRDGEVFVPRLVKATRSATGTATGTPDFGVGPVLLTGASGALGGLVARHLVAEH 5629 Query: 1206 GAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLA 1265 G ++L SRR + +VR D AD +A ++ P+ Sbjct: 5630 GVRSLLLLSRRGAEAPGAVELEAELAAWGAEVRWAACDAADRDALAEVLAGT-----PVT 5684 Query: 1266 GIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVW 1325 +VHAAG + ++ L +++V K +L E L +DL FV SS++ + Sbjct: 5685 AVVHAAGVLDDGVIAALTPERMEKVLRPKTDAVLNLHE----LTSDLSAFVVFSSVSGIL 5740 Query: 1326 GGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW--AAGMADAESRA---RLEQRGV 1380 G GQ Y AANAFLD A R RG+ A S+ +G W +GMAD +A RL++ G+ Sbjct: 5741 GSAGQGNYAAANAFLDAFAEARRARGLPATSLAWGLWEQGSGMADRLDQADLARLKRVGL 5800 Query: 1381 RTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAG--RRAFLSELESELXXXXXX 1438 ++ E L + D + VVA PL G + L Sbjct: 5801 APIAVDEGLR-LFDAALALDRAVVA--------PLRLDLGGLQGTVPPVLRGLRGTVRGT 5851 Query: 1439 XXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGM 1497 L ++L P +R+ ++ + +R VA V A ++ E F D G Sbjct: 5852 ARRMAQTAPKGSLGQRLAGLPQAEREQVVLDLVRAEVAAVLGHASAQAVQPEHAFQDAGF 5911 Query: 1498 DSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTAR 1557 DSL +VELR R+ G +PVT+V DHP + +LL E LG+ EQ A Sbjct: 5912 DSLTSVELRNRLNAATGLRLPVTMVFDHPTPVALSRFLLAETLGVQEQAEA--AIAAVTG 5969 Query: 1558 TDDPIAVVAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKT 1615 TD+ IA+V ++CRFPG PE W L+A G DAI PEDR WD++ YDPDPD GK+ Sbjct: 5970 TDEAIAIVGMACRFPGDVRSPEDLWRLVASGGDAISGFPEDRGWDVENLYDPDPDRSGKS 6029 Query: 1616 YTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTG 1675 Y R P FFGISPREA+ ++PQQRL+LET WE ERAG P+ +RGSRTG Sbjct: 6030 YVRHGGFLHEAAEFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATVRGSRTG 6089 Query: 1676 VFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSAL 1735 VF GV ++Y + + ++ + +G+A + SGRV++ G EGPAV VDTACSS+L Sbjct: 6090 VFAGVMYHDYGGRVKTAP-EGMDAYLGSGSAGSIASGRVSYTFGLEGPAVTVDTACSSSL 6148 Query: 1736 VAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRS 1795 VA+H A QAL+SG+C +AL GGV V+ +P T V SR R LS GRCK F A ADG + Sbjct: 6149 VALHLATQALRSGECSMALVGGVTVMATPSTFVEFSRQRGLSADGRCKAFAAGADGTGWA 6208 Query: 1796 EGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGL 1855 EG G+L+++RLSDA R+G V AV+ ++VNQDGAS+GLT PNG +QQR+I LA AG+ Sbjct: 6209 EGAGMLLVERLSDARRNGHTVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAGV 6268 Query: 1856 SGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAG 1915 S VD +EAHGTGT LGDPIE Q PL +GS+K+NIGH ++A+G G Sbjct: 6269 SSEQVDAVEAHGTGTKLGDPIEAQALIATYGQERPGDRPLWLGSLKSNIGHAQAAAGVGG 6328 Query: 1916 LIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTG 1975 +IK+V++++HG LP++LH + P+PH+ W A VR++ E + W RRA VSSFG +G Sbjct: 6329 VIKMVMAMRHGALPRTLHVDEPTPHVDWSAGDVRLLTEAMEWPETDHPRRAAVSSFGISG 6388 Query: 1976 TNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL--ALSARSPEALVELARRYDD 2033 TNAHV+VE+AP DS + + LS R+ AL A R Sbjct: 6389 TNAHVIVEQAPDTAELPP-------------VPDSGKAVPWVLSGRTEAALRAQAERL-- 6433 Query: 2034 WLSATPGLDI--ADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGE 2091 LS P +D+ AD+ + RS E+RAA+V +S VV GE Sbjct: 6434 -LSLVPEMDLPPADIGFSLATTRSAMEHRAAVVGESRDELLEGLRALAAGSPSTRVVLGE 6492 Query: 2092 HVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAEAVADMLPRPLLDVLFATD 2150 + +LF+GQGSQ GM REL+D PVFA + CA L+D D Sbjct: 6493 PGAGGKSGFLFSGQGSQRIGMGRELYDAFPVFAAAYDEVCA----------LVDAPVDVD 6542 Query: 2151 RETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDG 2210 E L T QPALFAVE+ L RL +SW I PD V GHSVG+ AAA VAGV SL+D Sbjct: 6543 SEE---LNQTGTTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLSLEDA 6599 Query: 2211 ARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGED-L 2269 A+L++ R + +LP G MVAV A + V + V + A NGP +V+ ED + Sbjct: 6600 AKLVSARAALMQALPADGAMVAVQATEDEV--LPHLTDGVGIAAVNGPQSVVVSGAEDVV 6657 Query: 2270 EEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVL 2329 I E F + G + + L SHAFHS L+DP+L+ P LP+V N TG + Sbjct: 6658 VAIGEAFRERGRKTSRLKVSHAFHSPLMDPMLEEFAEAVSGLSFNEPRLPVVSNLTGRLA 6717 Query: 2330 TGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAP 2389 TP +YW RH R+ V+FA+ + T+ LG + +EIGP VL+ A + Sbjct: 6718 EPYTP---EYWVRHVREAVRFADGLHTLHELGVTTFVEIGPGGVLSALAQGCLDGDIV-- 6772 Query: 2390 RAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKAS 2449 V ++R + + + ALA + G PD+ A+ RR V+LPTYPFQ R W +A Sbjct: 6773 -TVPAVRTDRPEPQAVVTALAELHAHGVSPDWRALFPGARR-VDLPTYPFQYERLWLEAP 6830 Query: 2450 SIAVDGGTAASGILGSG---KDLA--------SGDTIYTSRLSVKSQPWLADHVIYGTVV 2498 GTAA+ LG G LA +G + T RLS+++ PWLADH + +V+ Sbjct: 6831 EEYT--GTAAATGLGLGAAEHPLAGAAVALPGAGGFLVTGRLSLRTHPWLADHTVMDSVL 6888 Query: 2499 VPGATYAAMALAA--VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHS 2556 +PG +A+ A A+++D+ P+I+PE+ VQ+ + + + +HS Sbjct: 6889 LPGTALVELAVRAGEEAGCAQVEDLTLEAPLIVPERGGVAVQVWVEAEEEPGRCALSVHS 6948 Query: 2557 -RPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLE 2615 R A W +A G + A +P AD + P E + +E L Sbjct: 6949 RREDAPDDAPWVRHAVGRLTDALPEPPHGADLGAWPP----AGAEAVDLTGFYEGLDGLG 7004 Query: 2616 LAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXX 2675 L +GP + G L+S+W + + ++ + + G+ +HP L+D Sbjct: 7005 LGYGPVFRG-LRSVWRSGDDVLAEVALPE--GTEAGAFAVHPALLDAALHAVGAGGLVPV 7061 Query: 2676 XXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGG 2735 ++ LP + +V + + R + R+ D+ L D G + Sbjct: 7062 -----LDGPLLPFAWSEVGV--RAAGATALRVKLSRTGTDA----VSLTVADASGGLVAT 7110 Query: 2736 IREFTVKRAPREALLR--GLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAA- 2792 + +++ RE LL G G A L+ L W P + DA + + +LAA Sbjct: 7111 VGSLSLRPVSREQLLAAGGSGRRADDSLFGLAWQ--PAVLTETDAAAGLDVRSYADLAAL 7168 Query: 2793 KVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXI 2852 +P D+ V+ V A G+G Sbjct: 7169 STEPALP-----DVAVVTVVPCPA---GSG------------------------------ 7190 Query: 2853 TNLLSAVHAAQGPSVKLPGGLWIVTEH-GVACESGEPVDPVQAALWGFGRTTINEEPALH 2911 VH+ + L W+ E G P D AA+WG R+ +E P Sbjct: 7191 RETADRVHSTTSEVLALV-QWWLAEERAGRLALVTRPGDLAHAAVWGLVRSAQSENPD-R 7248 Query: 2912 CRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFV 2971 LV+ + + EAV EP+ AVR G++ RL+ RS T DF Sbjct: 7249 IVLVEAEETDEAVRVLPAAL---ASGEPQFAVRDGEVFVPRLVKATRSATGTATGTPDFG 7305 Query: 2972 LAP 2974 + P Sbjct: 7306 VGP 7308 Score = 859 bits (2219), Expect = 0.0 Identities = 676/1984 (34%), Positives = 937/1984 (47%), Gaps = 185/1984 (9%) Query: 1034 AASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQ 1093 AA+A + VV G GA R + V H L L + E + LVTR G Sbjct: 3766 AAAAADAVVVPCPTGTGADLATR-VREVTHAVL----ELVQWWLAEERPGRLVLVTRGGD 3820 Query: 1094 RVTDTDTVVPEQSCLWGFGRAAALELP------------HIWGGLADLSGAD-TEWPRLI 1140 QS + G R+A E P H G SG D + R++ Sbjct: 3821 LA---------QSAVCGLVRSAQTENPDRIVLVETSSDAHAGAG----SGVDDADLARVL 3867 Query: 1141 ARITSPRDGEDQIALRGD-AVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVA 1199 + + GE Q A+ D V PRLVR ++ LP T L+TG G +G A Sbjct: 3868 PGLIA--SGEPQAAVHADDEVRVPRLVRVAVPDAEPELPGLGSGTVLLTGASGGLGGLFA 3925 Query: 1200 GYL-ASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVA 1258 +L A HG ++L SRR DV DVAD V L+ A Sbjct: 3926 RHLVAEHGVRSLLLVSRRGGDAPGAAELTADLTAQGADVTWAACDVADRAAVRALL---A 3982 Query: 1259 AELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVST 1318 L+ I+H AG + + L +D VF KV A +L + +L DL FV Sbjct: 3983 GPGQSLSAIIHTAGVLDDGIIGSLTPERLDAVFRPKVDAALNLHDLAGELSGDLSAFVLF 4042 Query: 1319 SSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-------AGMADAES 1371 SS+A G GQ Y AAN FLD LA R G A S+ +G WA G D Sbjct: 4043 SSVAGTLGTPGQANYAAANTFLDALAEHRRAAGQRATSLAWGLWAQDSESAMTGSLDHTD 4102 Query: 1372 RARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAG--RRAFLSELE 1429 R+++ G+ + ++ L + D + VVA PL G + L Sbjct: 4103 LTRIQRMGLAAIPSSDGLR-LFDAALALDRAVVA--------PLRLDLGGLQGTVPPVLR 4153 Query: 1430 SELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRD 1488 L ++L +R+ ++ + +R VA V A + Sbjct: 4154 GLRGTVRGTARRTAQTAPKGSLGQRLAGLAEAEREQVVLDLVRTEVAAVLGHAGAQSVGA 4213 Query: 1489 EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNV 1548 + F D+G DSL AVELR R+ VG +P TL+ D+P A +L E G T V Sbjct: 4214 DDSFKDIGFDSLTAVELRNRLNSAVGMRLPATLIFDYPNPLTLAHFLTGEAAGGEAATAV 4273 Query: 1549 RQA-STVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDIDEFY 1605 ST T D+PIA+V ++CR+PG PE W+L+ G DA+ PE R WD+++ Y Sbjct: 4274 PTTLSTATGTADEPIAIVGMACRYPGGVQSPEDLWQLVFSGRDAVSGFPEGRGWDVEQLY 4333 Query: 1606 DPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYA 1665 DP+PD G +YTR EFFGISPREA+ ++PQQRL+LET WE ERAG Sbjct: 4334 DPNPDQWGTSYTREGGFLHDAADFDAEFFGISPREALAMDPQQRLLLETSWEAFERAGID 4393 Query: 1666 PSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAV 1725 P+ +RGSRTGVF GV ++Y + S +E + + G+A + SGRV++ G EGPAV Sbjct: 4394 PATVRGSRTGVFAGVMYHDYGGRVHT-SPPGLEGYLVNGSAGSIASGRVSYTFGLEGPAV 4452 Query: 1726 AVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTF 1785 VDTACSS+LVA+H A QAL+SG+C +AL GGV V+ P V SR R LS GRCK F Sbjct: 4453 TVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMAGPSVFVEFSRQRGLSADGRCKAF 4512 Query: 1786 DASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRL 1845 A ADG +EG G+L+++RLSDA R+G +V AV+ ++VNQDGAS+GLT PNG +QQR+ Sbjct: 4513 GAGADGTGWAEGVGMLLVERLSDARRNGHKVLAVVRGTAVNQDGASNGLTAPNGPSQQRV 4572 Query: 1846 IEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIG 1905 I LA AGLS +VD +EAHGTGT LGDPIE Q PL +GS+K+NIG Sbjct: 4573 IRQALANAGLSSDEVDAVEAHGTGTRLGDPIEAQALIATYGQERSEDRPLWLGSLKSNIG 4632 Query: 1906 HTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRR 1965 H+++A+G G+IK+V+++QHGVLPQ+LH + P+PH+ W A V+++ E V W + RR Sbjct: 4633 HSQAAAGVGGVIKMVMAMQHGVLPQTLHVDEPTPHVDWSAGAVQLLTEAVEWPASDGPRR 4692 Query: 1966 AGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTD-DSPQVLALSARSPEAL 2024 A VSSFG +GTNAHV+VE+A GT P LSA+S AL Sbjct: 4693 AAVSSFGVSGTNAHVIVEQAATS------------EVTARGTAVAGPVPWVLSAKSDAAL 4740 Query: 2025 VELARRYDDWLSAT----PGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXX 2080 E A R +L A G+ DV ++ R+ E RAA+V + + Sbjct: 4741 REQAGRLLSFLDAEGVGGAGVRPEDVAYSLATSRAVLECRAAVVGEELGEFRQGLEGIVS 4800 Query: 2081 XXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAEAVADMLP 2139 P G G V +LF+GQGSQ GM REL+ PVFA + CA Sbjct: 4801 GAAPVGGAVGGRV-----GFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCA-------- 4847 Query: 2140 RPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAA 2199 LLD D ET L T QPALFAVE+ L RL +SW I PD V GHSVG+ AAA Sbjct: 4848 --LLDATVDVDAET---LHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAA 4902 Query: 2200 CVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP- 2258 VAGV SL+D A+L++ R + +LP GG MVA+ A E + V + A NGP Sbjct: 4903 HVAGVLSLEDAAKLVSARAALMQALPAGGAMVAI--QATEAEVLPHLTHGVGLAAINGPR 4960 Query: 2259 NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTL 2318 + VLSG + + +I E F +G + + L SHAFHS L+DP+L+ P + Sbjct: 4961 SVVLSGSEDAVLDIAEVFAQQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSEPRI 5020 Query: 2319 PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAA 2378 P+V N TG + P +YW RH R+ V+FA+ + T+ LG ++ +EIGP VL+ A Sbjct: 5021 PVVSNLTGRLAEVYIP---EYWVRHVREAVRFADGLHTLHELGVTMFVEIGPGGVLS-AL 5076 Query: 2379 VQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYP 2438 VQ + V +LR + + A+ + G P++ A+ RR V+LPTY Sbjct: 5077 VQGCLDDGTHIVTVPALRADRPEPYALVTAVGQLHTHGISPEWQALFPGARR-VDLPTYA 5135 Query: 2439 FQRRRFW---PKASS--IAVDGGTAASGILGSGKDLASGD-TIYTSRLSVKSQPWLADHV 2492 FQR R+W P+AS A G A +LG+ A D + T LS+ + PWLADH Sbjct: 5136 FQRERYWLDAPQASGDVRAAGLGAADHPLLGAAIATADSDGAVLTGLLSLGTHPWLADHA 5195 Query: 2493 IYGTVVVPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHPADGGSVL 2550 + G V++PG + +A+ A ++D+ P+++PE+ +Q+ + P D Sbjct: 5196 VNGIVLLPGTAFVELAIRAGDETGCGWIEDLTLELPLVVPERGGVTLQVAVGPEDESGRR 5255 Query: 2551 SFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFET 2610 +HSR W +A G + +A + P AA P E + +E Sbjct: 5256 QLSVHSR---VDDRSWLRHATGVLSSAEA-PSAAKLGAWPPAG-----AEAVDLTAFYEG 5306 Query: 2611 FADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXX 2670 A L +GP + G L+S+W + ++ + E A + + +HP L+D Sbjct: 5307 MAAAGLDYGPVFQG-LRSVWRDGDDVFAEVELPDESAAEAAAFALHPALLDAALHALAAG 5365 Query: 2671 XXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGG 2730 LP + V + + R + R+A S T L D G Sbjct: 5366 GLVSLDDSPA-----LPFAWSGVVV--QAAGAAMVRVKLSRTATGSVT----LAVADGAG 5414 Query: 2731 RALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDEL 2790 + + +++ A E L +GGD L+ L W PSA DA+ +A FD L Sbjct: 5415 DPVASVESLSLRAASAEQLPGAVGGDQ---LFGLEWTRF-TLPSATDALMIETVADFDAL 5470 Query: 2791 AAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXX 2850 + G VV A GR+ Sbjct: 5471 -------------------------RESEGTPDVVVVPCPAGSGRETADRVHSTTSEVLA 5505 Query: 2851 XITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPAL 2910 + L+ A G L +VT G D AA+WG R+ +E P Sbjct: 5506 LVQWWLAEERA---------GRLALVTRPG---------DLAHAAVWGLVRSAQSENPD- 5546 Query: 2911 HCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDF 2970 LV+ + + EAV EP+ AVR G++ RL+ RS T DF Sbjct: 5547 RIVLVEAEETDEAVRVLPAAL---ASGEPQFAVRDGEVFVPRLVKATRSATGTATGTPDF 5603 Query: 2971 VLAP 2974 + P Sbjct: 5604 GVGP 5607 Score = 688 bits (1775), Expect = 0.0 Identities = 461/1153 (39%), Positives = 616/1153 (53%), Gaps = 73/1153 (6%) Query: 1339 FLDGLAWRLRERGV-TAVSVNFGPWAAGMADAESRAR-LEQRGVRTLSPAEALAGMADVV 1396 F DG+A RL E+GV T + + G A MA A + + L +RT P EA A +A V Sbjct: 808 FADGVA-RLDEQGVRTYLELGPGGVLASMARAGADSESLFVPALRTRRP-EAQALLAAVA 865 Query: 1397 AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXL----- 1451 + V GV + DW + A R+ L E Sbjct: 866 SLHVHGV--EPDWDALFGGGRGARRKVALPTYAFERQRYWLDGDTTSPVATTGWAPVAPQ 923 Query: 1452 ---VEQLTKAPV------------QQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDL 1495 + + APV +R + + +R +A V +A ++ E F DL Sbjct: 924 PDAIAETDSAPVGALGRRLAGLAESERDEAVLDMVRAHIAAVLGHAEARQVETEWTFKDL 983 Query: 1496 GMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVT 1555 G DSL +VELR ++ + G +P L+ DHP + A +L + LG G+ A Sbjct: 984 GFDSLSSVELRNQLSEATGLRLPSGLLFDHPTPAALARHLAAQSLGGGDA--AAAAPATV 1041 Query: 1556 ARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPG 1613 A +PIA+VA+SCR P G PE W LLA G D I P DR WD++ YDP+P TPG Sbjct: 1042 ADPHEPIAIVAMSCRLPGGVSSPEDLWRLLASGGDGISGFPTDRGWDVETLYDPEPGTPG 1101 Query: 1614 KTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSR 1673 K+ TR FFGISPREA I+PQQRL+LET WE ERAG P+ LRGSR Sbjct: 1102 KSSTRHGGFLHEAAEFDAGFFGISPREAAAIDPQQRLVLETAWEAFERAGIDPATLRGSR 1161 Query: 1674 TGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSS 1733 GVF G A +Y L E D +E + +TG + SGRVA++ G EGPAV VDTACSS Sbjct: 1162 AGVFIGATAQDYGPRLH-EPADGVEGYLLTGTTTSVASGRVAYSFGLEGPAVTVDTACSS 1220 Query: 1734 ALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYV 1793 +LVA+H A Q+L+SG+C +ALAGGV V+ +P V SR R LS GRCK F A ADG Sbjct: 1221 SLVALHLAVQSLRSGECTMALAGGVTVMSTPGMFVEFSRQRGLSADGRCKAFAAGADGTG 1280 Query: 1794 RSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARA 1853 +EG G+L+++RLSDA R+G +V AV+ S+VNQDGAS+GLT PNG +QQR++ LA A Sbjct: 1281 WAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRQALAAA 1340 Query: 1854 GLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGA 1913 GL+ ADVD +EAHGTGT LGDPIE + PL +GS+K+NIGHT++A+G Sbjct: 1341 GLAPADVDAVEAHGTGTLLGDPIEAEALIAAYGQGRDGDRPLWLGSLKSNIGHTQAAAGV 1400 Query: 1914 AGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGF 1973 AG+IK+V++++HGVLP++LH + P+PH+ W A VR++ E V W RRA VSSFG Sbjct: 1401 AGVIKMVMAMRHGVLPRTLHVDEPTPHVDWSASGVRLLTEAVEWPARDLPRRAAVSSFGI 1460 Query: 1974 TGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTD-DSPQVLALSARSPEALVELARRYD 2032 +GTNAHV+VE+A GT P +SA+S AL E A R Sbjct: 1461 SGTNAHVIVEQAATS------------EEPARGTAVAGPVPWVVSAKSDVALREQAGRLL 1508 Query: 2033 DWLSAT----PGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVV 2088 +L A G+ DV + R+ E RAA+V + + A V Sbjct: 1509 SFLDAEGVGGAGVRPEDVALSLATSRAVLERRAAVVGGDLAELRQGLEALASGASGAAPV 1568 Query: 2089 RGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAEAVADMLPRPLLDVLF 2147 G R +LF+GQGSQ GM REL+ PVFA + CA LD Sbjct: 1569 GGAVGGR--VGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCA----------FLDAPV 1616 Query: 2148 ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSL 2207 D E L T QPALFAVE+ L RL +SW I PD V GHSVG+ AAA VAGV SL Sbjct: 1617 DVDSEE---LNQTGTTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLSL 1673 Query: 2208 DDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-NTVLSGPG 2266 +D A+L++ R + +LP+GG MVAV A + V + + V + A NGP + V+SG Sbjct: 1674 EDAAKLVSARAALMQALPDGGAMVAVQATEDEVLRHLTD--GVGIAAVNGPRSVVVSGAE 1731 Query: 2267 EDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTG 2326 + + + E F G + + L SHAFHS L+DP+L+ +P+V N TG Sbjct: 1732 DAVTAVGEIFAGRGRKTSRLKVSHAFHSPLMDPMLEEFAAVVRGLTFSESRIPVVSNLTG 1791 Query: 2327 AVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHM 2386 + TP +YW RH R+ V+FA+ + T+ LG + +E+GP VL+ A + + Sbjct: 1792 RLAEVYTP---EYWVRHVREAVRFADGIETLGELGVTTFVEVGPGGVLSALAQGCFDDGT 1848 Query: 2387 AAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWP 2446 V LR + + A+ + G PD+ + RR V+LPTY FQR R+W Sbjct: 1849 DIV-TVPVLRADRPEPYALVTAIGRLHTHGISPDWQVLFPGARR-VDLPTYAFQRERYWL 1906 Query: 2447 KASSIAVDGGTAA 2459 A A G A Sbjct: 1907 DAPRAATAGAPDA 1919 Score = 656 bits (1692), Expect = 0.0 Identities = 388/902 (43%), Positives = 519/902 (57%), Gaps = 40/902 (4%) Query: 13 SFAIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTR 70 + AI+G A RFPG S E+ W L+ G +AIS P+DR WD+E +DPDP GK R Sbjct: 5973 AIAIVGMACRFPGDVRSPEDLWRLVASGGDAISGFPEDRGWDVENLYDPDPDRSGKSYVR 6032 Query: 71 RAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFV 130 GF+ + FD FFG+S RE MDPQ R+L+ET+W A E +GI P ++ S TGVF Sbjct: 6033 HGGFLHEAAEFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATVRGSRTGVFA 6092 Query: 131 GLATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLV 189 G+ HDY G T PE ++AY+ G++ + A+GR+SY GL+GPAV VDTACSSSLV Sbjct: 6093 GVMYHDYGGRVK---TAPEGMDAYLGSGSAGSIASGRVSYTFGLEGPAVTVDTACSSSLV 6149 Query: 190 AIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGE 249 A+H A QALR EC +AL GG V+ TP+T + FS L+ DGRCK F A ADG E Sbjct: 6150 ALHLATQALRSGECSMALVGGVTVMATPSTFVEFSRQRGLSADGRCKAFAAGADGTGWAE 6209 Query: 250 GCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLR 309 G G+++V+RL DA R+G + AV+RG+A+NQDGAS GLT PNG +QQRVI AL AG+ Sbjct: 6210 GAGMLLVERLSDARRNGHTVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAGVS 6269 Query: 310 PADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXX 369 V +EAHGTGT LGDPIEAQA G R + PL +GS K+NIGH + Sbjct: 6270 SEQVDAVEAHGTGTKLGDPIEAQALIATYGQERPGDRPLWLGSLKSNIGHAQAAAGVGGV 6329 Query: 370 XXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGT 429 + + LP+ L+ + P+PH+ W + ++ E + W PR A VSSFG +GT Sbjct: 6330 IKMVMAMRHGALPRTLHVDEPTPHVDWSAGDVRLLTEAMEWPETDHPRRAAVSSFGISGT 6389 Query: 430 NAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLA 489 NAHVI+E+AP A PV D + LS RT EA +R E L A Sbjct: 6390 NAHVIVEQAP---DTAELPPVPDSGKAVPWVLSGRT-EAALRAQAERLLSLVPEMDLPPA 6445 Query: 490 DVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTG 549 D+ + T R+ +E RAA+V SR+ +E L ALA P+ +V GE K+ +LF+G Sbjct: 6446 DIGFSLATTRSAMEHRAAVVGESRDELLEGLRALAAGSPSTRVVLGEPGAGGKSGFLFSG 6505 Query: 550 QGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTT 609 QGSQ GM REL+D PVFA + V +++ P +D D+E L T Sbjct: 6506 QGSQRIGMGRELYDAFPVFAAAY----DEVCALVDAP----------VDVDSEE-LNQTG 6550 Query: 610 YAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLF 669 QPALFAVE+ L RL +SWG PD V GHSVG+ +AA VAGV +ED A+L++ R L Sbjct: 6551 TTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLSLEDAAKLVSARAALM 6610 Query: 670 GSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVAD- 727 +LPA G M AV T E LTD + +AA NG +V+ A+D+ A+ + Sbjct: 6611 QALPADGAMVAVQATEDEVLPHLTD---GVGIAAVNGPQSVVVSGAEDVVVAIGEAFRER 6667 Query: 728 GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAY 787 G + L SHAFHS L+DP+L++F L + EP+ ++ N TG T Y Sbjct: 6668 GRKTSRLKVSHAFHSPLMDPMLEEFAEAVSGLSFNEPRLPVVSNLTGRLAEPYT---PEY 6724 Query: 788 WRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTT 847 W RH R+ V FA + TL ++ +EIGP VL+A A T + + RP Sbjct: 6725 WVRHVREAVRFADGLHTLHELGVTTFVEIGPGGVLSALAQGCLDGDIVTVPAVRTDRP-- 6782 Query: 848 ADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTA 907 + + + A+A +A G PD+RA P AR++DLPTYPF++ + W A + T TA Sbjct: 6783 -EPQAVVTALAELHAHGVSPDWRAL-FPGARRVDLPTYPFQYERLWL---EAPEEYTGTA 6837 Query: 908 SA 909 +A Sbjct: 6838 AA 6839 Score = 620 bits (1600), Expect = e-174 Identities = 377/918 (41%), Positives = 516/918 (56%), Gaps = 50/918 (5%) Query: 3 SAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPD 60 +A+ PI AI+G A R+PG S E+ W L+ GR+A+S P+ R WD+E+ +DP+ Sbjct: 4283 TADEPI------AIVGMACRYPGGVQSPEDLWQLVFSGRDAVSGFPEGRGWDVEQLYDPN 4336 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P G TR GF+ D FDA FFG+S RE MDPQ R+L+ET+W A E +GI P + Sbjct: 4337 PDQWGTSYTREGGFLHDAADFDAEFFGISPREALAMDPQQRLLLETSWEAFERAGIDPAT 4396 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 + S TGVF G+ HDY G + P +E Y+ G++ + A+GR+SY GL+GPAV V Sbjct: 4397 VRGSRTGVFAGVMYHDYGGRV--HTSPPGLEGYLVNGSAGSIASGRVSYTFGLEGPAVTV 4454 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVA+H A QALR EC +AL GG V+ P+ + FS L+ DGRCK F A Sbjct: 4455 DTACSSSLVALHLAAQALRSGECSMALVGGVTVMAGPSVFVEFSRQRGLSADGRCKAFGA 4514 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 ADG EG G+++V+RL DA R+G ++ AV+RG+A+NQDGAS GLT PNG +QQRVI Sbjct: 4515 GADGTGWAEGVGMLLVERLSDARRNGHKVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIR 4574 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 AL AGL +V +EAHGTGT LGDPIEAQA G R+ + PL +GS K+NIGH Sbjct: 4575 QALANAGLSSDEVDAVEAHGTGTRLGDPIEAQALIATYGQERSEDRPLWLGSLKSNIGHS 4634 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 + +++ LP+ L+ + P+PH+ W ++++ E V W + PR A Sbjct: 4635 QAAAGVGGVIKMVMAMQHGVLPQTLHVDEPTPHVDWSAGAVQLLTEAVEWPASDGPRRAA 4694 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL 480 VSSFG +GTNAHVI+E+A A V P + LSA++ AL AG +L Sbjct: 4695 VSSFGVSGTNAHVIVEQAATSEVTARGTAVAGPVPW---VLSAKSDAALREQAGRLLSFL 4751 Query: 481 RAH----PQARLADVSHTAGTARAHLEQRAALVVNS-RESAIELLGALADDRPAPGLVRG 535 A R DV+++ T+RA LE RAA+V E L G ++ P G V G Sbjct: 4752 DAEGVGGAGVRPEDVAYSLATSRAVLECRAAVVGEELGEFRQGLEGIVSGAAPVGGAVGG 4811 Query: 536 ESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRK-CAEAVADILEKPLLDVIFDA 594 + +LF+GQGSQ GM REL+ PVFA + CA LLD D Sbjct: 4812 ------RVGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCA----------LLDATVDV 4855 Query: 595 DELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFD 654 D L T QPALFAVE+ L RL +SWG PD V GHSVG+ +AA VAGV Sbjct: 4856 D------AETLHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLS 4909 Query: 655 VEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPA 714 +ED A+L++ R L +LPAGG M A+ AE L + +AA NG +V+ + Sbjct: 4910 LEDAAKLVSARAALMQALPAGGAMVAI--QATEAEVLPHLTHGVGLAAINGPRSVVLSGS 4967 Query: 715 KDLESAVATLVA-DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRT 773 +D +A + A G + L SHAFHS L+DP+L++F + L + EP+ ++ N T Sbjct: 4968 EDAVLDIAEVFAQQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSEPRIPVVSNLT 5027 Query: 774 GSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDP 833 G + YW RH R+ V FA + TL ++ + +EIGP VL+A D Sbjct: 5028 GRL---AEVYIPEYWVRHVREAVRFADGLHTLHELGVTMFVEIGPGGVLSALVQGCL-DD 5083 Query: 834 ATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFW 893 T + +LR + + AV + G P+++A P AR++DLPTY F+ ++W Sbjct: 5084 GTHIVTVPALRADRPEPYALVTAVGQLHTHGISPEWQAL-FPGARRVDLPTYAFQRERYW 5142 Query: 894 FSDNRAIDRDTQTASAGS 911 +A D + A G+ Sbjct: 5143 LDAPQA-SGDVRAAGLGA 5159 Score = 612 bits (1577), Expect = e-172 Identities = 383/964 (39%), Positives = 526/964 (54%), Gaps = 53/964 (5%) Query: 15 AIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAGF 74 A+IG A R PGAA +W LL +G +AI+DVP DRWD D S P + RR GF Sbjct: 25 AVIGLACRLPGAADPAAFWRLLSEGADAITDVPPDRWDGAVV--ADASAPDRTGIRRGGF 82 Query: 75 VDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLAT 134 +D + FDA FFG+S +E MDPQ R+++E AW A+E + + +L ++ TGVFVG Sbjct: 83 LDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALEDAHVRAATLRSTRTGVFVGAMW 142 Query: 135 HDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQA 194 DY + I + G + A R+SY LGL GP++ VD+ SSSLV++H A Sbjct: 143 DDYATL-HHRSGLTAISPHTVTGLHRSIIANRVSYFLGLNGPSLTVDSGQSSSLVSVHLA 201 Query: 195 CQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVV 254 C++LR E +ALAGG N+ + P + + + L+PDGRC TFDA A+GYVRGEG G+V Sbjct: 202 CESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDGRCFTFDARANGYVRGEGGGIV 261 Query: 255 VVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVG 314 V+K L AV DGD + VIRGSA+N DG GLTVP Q++V+ A +RAG+ PADVG Sbjct: 262 VLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQSGQEQVLRLAYERAGVNPADVG 321 Query: 315 YLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXXX 374 Y+E HGTGT +GDPIEA A G VLG GR P PL +GSAKTN+GHLE Sbjct: 322 YVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSAKTNVGHLEGAAGITGLLKAVL 381 Query: 375 XLENETLPKHLNFETPSPHIPWERLPIEVVRETVPW-QRNGKPRIAGVSSFGFAGTNAHV 433 L + LP LNF TP+P IP +RL + V E W +G+P +AGVSSFG GTN H+ Sbjct: 382 SLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAEDGRPLLAGVSSFGMGGTNCHI 441 Query: 434 ILEEAPAV--GTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQA----R 487 +L AV G AT P + PLSA+T L A L AH +A Sbjct: 442 VLASGAAVEAGEGATAGGGAAP---TFWPLSAKTASGLRAQAAA----LLAHTEAPLGLA 494 Query: 488 LADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLF 547 L DV + T R E RA +V R+ + L L+ L G + + A+LF Sbjct: 495 LPDVGWSLATGRTAFEHRAVVVGEVRDDFLRALRELSTGGIDAALTTGRAGPRGELAFLF 554 Query: 548 TGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIF------DADELDGDT 601 +GQGSQ GM REL ++ P FA + + + +L +PL +V+F +A ELD Sbjct: 555 SGQGSQRAGMGRELAESVPAFASALDEVCAHLDPLLPRPLREVMFAPVGTGEAAELD--- 611 Query: 602 ESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARL 661 T Y Q +LFAVE+ L RL +SW PDV++GHS+G+ +AA VAGV + D L Sbjct: 612 -----QTLYTQTSLFAVEVALFRLLESWDITPDVLMGHSIGELAAAHVAGVLSLADACAL 666 Query: 662 IAERGRLFGSLPAGGRMAAVFTAPERAE-RLTDEYPSLSVAAYNGANTVLSGPAKDLESA 720 +A RGRL +LPAGG M AV A + R+ + +S+AA NG ++V+ +DL + Sbjct: 667 VAARGRLMQALPAGGAMIAVQAAEDEVRARIGERTDRVSIAALNGPDSVVVSGDEDLATE 726 Query: 721 VA-TLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 +A A G + L SHAFHS ++P+L +F + A+ L + P+ ++ N TG Sbjct: 727 IADAFAALGRKTSRLRVSHAFHSPHMEPMLAEFRNVAEGLTFHAPRIPIVSNVTGRLSEE 786 Query: 780 STRLDG---AYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATT 836 + +G AYW RH R+ V FA V L + R LE+GP VL + A A + Sbjct: 787 PSGYEGCTAAYWVRHVREAVRFADGVARLDEQGVRTYLELGPGGVLASMARAGADSESLF 846 Query: 837 PQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAF---RQPDARKLDLPTYPFEHRQFW 893 L + RP + + + AVA+ + G PD+ A + RK+ LPTY FE +++W Sbjct: 847 VPALRTRRP---EAQALLAAVASLHVHGVEPDWDALFGGGRGARRKVALPTYAFERQRYW 903 Query: 894 FSDNRAIDRDT----QTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLN 949 +D DT T V P + A+ + + L + G E+ VL+ Sbjct: 904 ------LDGDTTSPVATTGWAPVAP-QPDAIAETDSAPVGALGRRLAGLAESERDEAVLD 956 Query: 950 KLAA 953 + A Sbjct: 957 MVRA 960 Score = 595 bits (1535), Expect = e-167 Identities = 368/905 (40%), Positives = 499/905 (55%), Gaps = 28/905 (3%) Query: 1553 TVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTP 1612 + +A + D IAV+ ++CR PGA DP +FW LL+ G DAI +VP DRWD D P Sbjct: 15 SASADSADGIAVIGLACRLPGAADPAAFWRLLSEGADAITDVPPDRWD--GAVVADASAP 72 Query: 1613 GKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGS 1672 +T R FFG+SP+EA ++PQQRL+LE WE LE A + LR + Sbjct: 73 DRTGIRRGGFLDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALEDAHVRAATLRST 132 Query: 1673 RTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACS 1732 RTGVF G ++YA L + I PH +TG + I+ RV++ LG GP++ VD+ S Sbjct: 133 RTGVFVGAMWDDYATLHHRSGLTAISPHTVTGLHRSIIANRVSYFLGLNGPSLTVDSGQS 192 Query: 1733 SALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGY 1792 S+LV+VH AC++L+ G+ +ALAGGVN+ + P + + A++ LSP GRC TFDA A+GY Sbjct: 193 SSLVSVHLACESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDGRCFTFDARANGY 252 Query: 1793 VRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLAR 1852 VR EG G++VLK L+ AV DGD V VI S+VN DG GLTVP Q++++ R Sbjct: 253 VRGEGGGIVVLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQSGQEQVLRLAYER 312 Query: 1853 AGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASG 1912 AG++ ADV Y+E HGTGT +GDPIE PL +GS KTN+GH E A+G Sbjct: 313 AGVNPADVGYVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSAKTNVGHLEGAAG 372 Query: 1913 AAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT-NGRVRRAGVSSF 1971 GL+K VLSL H LP SL+F P+P IP D L +RV E W +GR AGVSSF Sbjct: 373 ITGLLKAVLSLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAEDGRPLLAGVSSF 432 Query: 1972 GFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRY 2031 G GTN H+++ G +P LSA++ L A Sbjct: 433 GMGGTNCHIVLASG---------AAVEAGEGATAGGGAAPTFWPLSAKTASGLRAQAAAL 483 Query: 2032 DDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGE 2091 A GL + DV + GR+ FE+RA +V + A + G Sbjct: 484 LAHTEAPLGLALPDVGWSLATGRTAFEHRAVVVGEVRDDFLRALRELSTGGIDAALTTGR 543 Query: 2092 HVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFAT-- 2149 R A+LF+GQGSQ GM REL ++ P FA + + + +LPRPL +V+FA Sbjct: 544 AGPRGELAFLFSGQGSQRAGMGRELAESVPAFASALDEVCAHLDPLLPRPLREVMFAPVG 603 Query: 2150 DRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDD 2209 E A+L Q T + Q +LFAVE+ L RL +SW I PDV++GHS+G+ AAA VAGV SL D Sbjct: 604 TGEAAELDQ-TLYTQTSLFAVEVALFRLLESWDITPDVLMGHSIGELAAAHVAGVLSLAD 662 Query: 2210 GARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGE-FPRVSVGAYNGPNTVLSGPGED 2268 L+A RGR+ +LP GG M+AV A + V GE RVS+ A NGP++V+ ED Sbjct: 663 ACALVAARGRLMQALPAGGAMIAVQAAEDEVRARIGERTDRVSIAALNGPDSVVVSGDED 722 Query: 2269 L-EEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGA 2327 L EI + F G + + L SHAFHS ++P+L P +P+V N TG Sbjct: 723 LATEIADAFAALGRKTSRLRVSHAFHSPHMEPMLAEFRNVAEGLTFHAPRIPIVSNVTGR 782 Query: 2328 VL---TGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG-AAVQVWP 2383 + +G A YW RH R+ V+FA+ V + G +E+GP VL A Sbjct: 783 LSEEPSGYEGCTAAYWVRHVREAVRFADGVARLDEQGVRTYLELGPGGVLASMARAGADS 842 Query: 2384 EHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVH---RQPRRPVELPTYPFQ 2440 E + P +LR + + + A+AS +V G PD+ A+ R RR V LPTY F+ Sbjct: 843 ESLFVP----ALRTRRPEAQALLAAVASLHVHGVEPDWDALFGGGRGARRKVALPTYAFE 898 Query: 2441 RRRFW 2445 R+R+W Sbjct: 899 RQRYW 903 Score = 149 bits (375), Expect = 1e-32 Identities = 155/536 (28%), Positives = 226/536 (42%), Gaps = 42/536 (7%) Query: 1021 SDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAE 1080 S AD A L + VV AG G R+ H T + L + E Sbjct: 7161 SYADLAALSTEPALPDVAVVTVVPCPAGSG-----RETADRVHSTTSEVLALVQWWLAEE 7215 Query: 1081 LRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI 1140 + LVTR G + +WG R+A E P L + D L Sbjct: 7216 RAGRLALVTRPGDLA---------HAAVWGLVRSAQSENPDRIV-LVEAEETDEAVRVLP 7265 Query: 1141 ARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT--YLVTGGLGAIGLEV 1198 A + S GE Q A+R V+ PRLV+ T + T + L+TG GA+G V Sbjct: 7266 AALAS---GEPQFAVRDGEVFVPRLVKATRSATGTATGTPDFGVGPVLLTGASGALGGLV 7322 Query: 1199 AGYL-ASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTV 1257 A +L A HG ++L SRR + +VR DVAD V+ ++ + Sbjct: 7323 ARHLVAEHGVRSLLLLSRRGAEAPGAVELEAELAAWGAEVRWAACDVADREAVSGMLNGL 7382 Query: 1258 AAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVS 1317 + L+ +VH AG +G ++ L + VF KV +L E D+ L FV Sbjct: 7383 GEQ--SLSAVVHTAGVLGDGIVASLTPERMREVFRPKVDAVLNLHECTRDM--GLAAFVV 7438 Query: 1318 TSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW------AAGMADAES 1371 SS+A + G GQ +Y AAN+FLD + R G+ A+S+ +G W G+ +A+ Sbjct: 7439 FSSVAGMVGSAGQASYAAANSFLDAFSAHRRREGLPAISLAWGVWEQSGAMTDGLVEAD- 7497 Query: 1372 RARLEQRGVRTLSPAEALAGMADVVAGPVQGVVA--KIDWSRFLPLYQQAGRRAFLSELE 1429 RAR+ + GV L P E L + D + V+A +ID RA + Sbjct: 7498 RARMARSGVLPLPPEEGLR-LFDAALASDEAVLAPVRIDTGALRAGEAPPVLRALVPAAA 7556 Query: 1430 SELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADE-IRD 1488 + L E+L + P +R+ + + +R VA +D +R Sbjct: 7557 AR------RTARAAAAPSASSLAERLEEMPEAEREKTVLDLVRAEVAAGLGHASDRTVRP 7610 Query: 1489 EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGE 1544 E F DLG DSL AVELR R+ + G +P TLV DHP + A ++ + G E Sbjct: 7611 EHAFQDLGFDSLTAVELRNRLNKATGLRLPATLVFDHPTPALLARHVFMAAAGAAE 7666 Score = 142 bits (357), Expect = 1e-30 Identities = 114/369 (30%), Positives = 160/369 (43%), Gaps = 22/369 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G A +LA GA +VLTSRR PD + E ++ A D Sbjct: 2180 LVTGGTGALGGQVARWLAGAGAEHLVLTSRRGPDAPGAAELKAELEELGAQVTVVACDAA 2239 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASH-XXXX 3416 D +A+L R + H AGVLDD L+ + PER L PK A H Sbjct: 2240 DRDALAELFGRYIVN-----AVVHTAGVLDDGLVESLTPERLNHVLRPKVDAALHLHELT 2294 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQ Y ANA LD L RRAQG+ A + +G W GG Sbjct: 2295 RDRQDLDAFVLFSSMTGVWGNGGQGAYGAANAFLDALAEHRRAQGVPALAVAWGSWADGG 2354 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPI 3536 MA AA ++ +G+ + A+ L + +G TV +W+R RP Sbjct: 2355 MADG-AAGDHLRRRGVRAIAALPAISVLHGALTHGETSMTVADVDWERFVPAFVGTRPCP 2413 Query: 3537 LDLVLPSA--AGEATGD---------SELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA 3585 L L +P A A EA S L+++L+ ++ + + ++ + L Sbjct: 2414 LLLGVPEAREALEARARAAQSPEVPVSALVQRLLGATPGEQGRILLDLVREQAATVLGHT 2473 Query: 3586 SPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A A F + G DSL A+ELR+RL++ G + T VFD+PT LA +L +L Sbjct: 2474 GKGAFEADRTFRETGFDSLTAVELRHRLNTATG--LRLPTTLVFDHPTPTALARHLGEEL 2531 Query: 3644 PDAEAPETA 3652 ETA Sbjct: 2532 LGRHGLETA 2540 Score = 134 bits (338), Expect = 2e-28 Identities = 111/365 (30%), Positives = 161/365 (44%), Gaps = 20/365 (5%) Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TG GA+G A +L A+ G ++L SRR + ++ + A DV Sbjct: 7310 LLTGASGALGGLVARHLVAEHGVRSLLLLSRRGAEAPGAVELEAELAAWGAEVRWAACDV 7369 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D V+ +L + + L+ + H AGVL D ++++ PER R PK + Sbjct: 7370 ADREAVSGMLNGLGEQ--SLSAVVHTAGVLGDGIVASLTPERMREVFRPKVDAVLNLHEC 7427 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQA+YA AN+ LD A RR +GL A + +G W Q G Sbjct: 7428 TRDMGLAAFVVFSSVAGMVGSAGQASYAAANSFLDAFSAHRRREGLPAISLAWGVWEQSG 7487 Query: 3477 MASS---EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSAR 3533 + EA A + G++PL P L +A S +A + A G A Sbjct: 7488 AMTDGLVEADRARMARSGVLPLPPEEGLRLFDAALA--SDEAVLAPVRIDTGALRAGEA- 7544 Query: 3534 PPILDLVLPSAAGEAT-------GDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 PP+L ++P+AA T S L ++L E+P +R V + ++ EV L AS Sbjct: 7545 PPVLRALVPAAAARRTARAAAAPSASSLAERLEEMPEAEREKTVLDLVRAEVAAGLGHAS 7604 Query: 3587 PPAA--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLP 3644 F DLG DSL A+ELRNRL+ G + AT VFD+PT LA ++ Sbjct: 7605 DRTVRPEHAFQDLGFDSLTAVELRNRLNKATG--LRLPATLVFDHPTPALLARHVFMAAA 7662 Query: 3645 DAEAP 3649 A P Sbjct: 7663 GAAEP 7667 Score = 118 bits (296), Expect = 2e-23 Identities = 105/357 (29%), Positives = 154/357 (43%), Gaps = 25/357 (7%) Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TG GA+G A +L A+ G ++L SRR + ++ + A D Sbjct: 5609 LLTGASGALGGLVARHLVAEHGVRSLLLLSRRGAEAPGAVELEAELAAWGAEVRWAACDA 5668 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D +A++LA P+ + H AGVLDD +++A PER L PK + Sbjct: 5669 ADRDALAEVLAGT-----PVTAVVHAAGVLDDGVIAALTPERMEKVLRPKTDAVLN--LH 5721 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG- 3475 GQ NYA ANA LD RRA+GL AT + +G W QG Sbjct: 5722 ELTSDLSAFVVFSSVSGILGSAGQGNYAAANAFLDAFAEARRARGLPATSLAWGLWEQGS 5781 Query: 3476 GMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSAR 3533 GMA +A A + GL P+ L +A L+ + L Sbjct: 5782 GMADRLDQADLARLKRVGLAPIAVDEGLRLFDAALALDRAVVAPLRLD----LGGLQGTV 5837 Query: 3534 PPILDLVLPSAAGEA------TGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 PP+L + + G A L ++L +P +R V + ++ EV L AS Sbjct: 5838 PPVLRGLRGTVRGTARRMAQTAPKGSLGQRLAGLPQAEREQVVLDLVRAEVAAVLGHASA 5897 Query: 3588 PAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 A F D G DSL ++ELRNRL++ G + + T VFD+PT L+ +L+ + Sbjct: 5898 QAVQPEHAFQDAGFDSLTSVELRNRLNAATGLRLPV--TMVFDHPTPVALSRFLLAE 5952 Score = 117 bits (292), Expect = 4e-23 Identities = 109/367 (29%), Positives = 150/367 (40%), Gaps = 25/367 (6%) Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TG G +G A +L A+ G ++L SRR D + + A DV Sbjct: 3912 LLTGASGGLGGLFARHLVAEHGVRSLLLVSRRGGDAPGAAELTADLTAQGADVTWAACDV 3971 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXX 3414 D A V LLA L+ I H AGVLDD ++ + PER PK A H Sbjct: 3972 ADRAAVRALLA---GPGQSLSAIIHTAGVLDDGIIGSLTPERLDAVFRPKVDAALNLHDL 4028 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 PGQANYA AN LD L RRA G AT + +G W Q Sbjct: 4029 AGELSGDLSAFVLFSSVAGTLGTPGQANYAAANTFLDALAEHRRAAGQRATSLAWGLWAQ 4088 Query: 3475 GGMASSEAA-----TANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVL 3529 ++ + I GL + S L +A L+ + L Sbjct: 4089 DSESAMTGSLDHTDLTRIQRMGLAAIPSSDGLRLFDAALALDRAVVAPLRLD----LGGL 4144 Query: 3530 GSARPPILDLVLPSAAGEATGDSE------LLKQLMEIPIPQRAGFVTEFLQREVQNFLR 3583 PP+L + + G A ++ L ++L + +R V + ++ EV L Sbjct: 4145 QGTVPPVLRGLRGTVRGTARRTAQTAPKGSLGQRLAGLAEAEREQVVLDLVRTEVAAVLG 4204 Query: 3584 LASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 A + A F D+G DSL A+ELRNRL+S G + AT +FDYP LA +L G Sbjct: 4205 HAGAQSVGADDSFKDIGFDSLTAVELRNRLNSAVG--MRLPATLIFDYPNPLTLAHFLTG 4262 Query: 3642 QLPDAEA 3648 + EA Sbjct: 4263 EAAGGEA 4269 >tr|Q93H87|Q93H87_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 6048 Score = 1604 bits (4153), Expect = 0.0 Identities = 1083/2863 (37%), Positives = 1466/2863 (51%), Gaps = 172/2863 (6%) Query: 9 EPTPSFAIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGK 66 +P AI+ + R PG S+ E+ W LL G + IS P DR WD+E +DP+P TPGK Sbjct: 1043 DPHEPIAIVAMSCRLPGGVSSPEDLWRLLASGGDGISGFPTDRGWDVETLYDPEPGTPGK 1102 Query: 67 VVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNT 126 TR GF+ + FDA FFG+S RE +DPQ R+++ETAW A E +GI P +L S Sbjct: 1103 SSTRHGGFLHEAAEFDAGFFGISPREAAAIDPQQRLVLETAWEAFERAGIDPATLRGSRA 1162 Query: 127 GVFVGLATHDYLGMASDELTYPE--IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTAC 184 GVF+G DY L P +E Y+ GT+ + A+GR++Y GL+GPAV VDTAC Sbjct: 1163 GVFIGATAQDY----GPRLHEPADGVEGYLLTGTTTSVASGRVAYSFGLEGPAVTVDTAC 1218 Query: 185 SSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADG 244 SSSLVA+H A Q+LR EC +ALAGG V+ TP + FS L+ DGRCK F A ADG Sbjct: 1219 SSSLVALHLAVQSLRSGECTMALAGGVTVMSTPGMFVEFSRQRGLSADGRCKAFAAGADG 1278 Query: 245 YVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALK 304 EG G+++V+RL DA R+G ++ AV+RGSA+NQDGAS GLT PNG +QQRV+ AL Sbjct: 1279 TGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRQALA 1338 Query: 305 RAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXX 364 AGL PADV +EAHGTGT LGDPIEA+A G GR + PL +GS K+NIGH + Sbjct: 1339 AAGLAPADVDAVEAHGTGTLLGDPIEAEALIAAYGQGRDGDRPLWLGSLKSNIGHTQAAA 1398 Query: 365 XXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSF 424 + + LP+ L+ + P+PH+ W + ++ E V W PR A VSSF Sbjct: 1399 GVAGVIKMVMAMRHGVLPRTLHVDEPTPHVDWSASGVRLLTEAVEWPARDLPRRAAVSSF 1458 Query: 425 GFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAH- 483 G +GTNAHVI+E+A PA V P + V SA++ AL AG +L A Sbjct: 1459 GISGTNAHVIVEQAATSEEPARGTAVAGPVPWVV---SAKSDVALREQAGRLLSFLDAEG 1515 Query: 484 ---PQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDR----PAPGLVRGE 536 R DV+ + T+RA LE+RAA+V + L ALA P G V G Sbjct: 1516 VGGAGVRPEDVALSLATSRAVLERRAAVVGGDLAELRQGLEALASGASGAAPVGGAVGG- 1574 Query: 537 SHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADE 596 + +LF+GQGSQ GM REL+ PVFA + V L+ P+ Sbjct: 1575 -----RVGFLFSGQGSQRIGMGRELYAAYPVFAAAY----DEVCAFLDAPV--------- 1616 Query: 597 LDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVE 656 D D+E L T QPALFAVE+ L RL +SWG PD V GHSVG+ +AA VAGV +E Sbjct: 1617 -DVDSEE-LNQTGTTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLSLE 1674 Query: 657 DGARLIAERGRLFGSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGANTVLSGPAK 715 D A+L++ R L +LP GG M AV T E LTD + +AA NG +V+ A+ Sbjct: 1675 DAAKLVSARAALMQALPDGGAMVAVQATEDEVLRHLTD---GVGIAAVNGPRSVVVSGAE 1731 Query: 716 DLESAVATLVAD-GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTG 774 D +AV + A G + L SHAFHS L+DP+L++F + + L + E + ++ N TG Sbjct: 1732 DAVTAVGEIFAGRGRKTSRLKVSHAFHSPLMDPMLEEFAAVVRGLTFSESRIPVVSNLTG 1791 Query: 775 SALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPA 834 T YW RH R+ V FA + TL ++ +E+GP VL+A A + D Sbjct: 1792 RLAEVYTP---EYWVRHVREAVRFADGIETLGELGVTTFVEVGPGGVLSALAQGCFDD-G 1847 Query: 835 TTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWF 894 T + LR + + A+ + G PD++ P AR++DLPTY F+ ++W Sbjct: 1848 TDIVTVPVLRADRPEPYALVTAIGRLHTHGISPDWQVLF-PGARRVDLPTYAFQRERYWL 1906 Query: 895 SDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAAR 954 RA A+AG+ + +E L AL+ E + V +KL+A Sbjct: 1907 DAPRA-------ATAGAPDAMDAEFWDSVESEDRASLGALLGLEPTELDV--VASKLSAW 1957 Query: 955 HNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQ 1014 ++R RY I W +V ++TA + +A+ AG Sbjct: 1958 RRKRREQSTTDGWRYRITWQPLDDMVRAAPSGTWLYVVSEETA----WTEAIRAGLTELG 2013 Query: 1015 IVALP---GSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRR 1071 + +P G D D L A + + AA G A L L Sbjct: 2014 VALVPFAVGEDTDRDALARAFADAGQEQADGILFAAAQGEAGA---------NALQRLVL 2064 Query: 1072 LFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLS 1130 L +A DA + +P+W +T D + P + LWG GR ALE P WGGL DL Sbjct: 2065 LVQALGDAGIEAPLWCLTSGAVSTGTADLLTDPVSAQLWGLGRIVALEQPQRWGGLVDLP 2124 Query: 1131 GA-DTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRR--TGEPSDTPLPVREDRTYLV 1187 D+ +A + + D EDQ+A+R VY RLVR + P+D P R T LV Sbjct: 2125 AELDSRALERLAGLLAQAD-EDQLAVRASGVYGRRLVRAPLSAAPADAPWSPRG--TVLV 2181 Query: 1188 TGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADA 1247 TGG GA+G +VA +LA GA H+VLTSRR P E+ V V+ D AD Sbjct: 2182 TGGTGALGGQVARWLAGAGAEHLVLTSRRGPDAPGAAELKAELEELGAQVTVVACDAADR 2241 Query: 1248 HDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTD 1307 +A L +VH AG + + L ++ V KV A HL E D Sbjct: 2242 DALAELFGRYIVN-----AVVHTAGVLDDGLVESLTPERLNHVLRPKVDAALHLHELTRD 2296 Query: 1308 LRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-AGM 1366 R DLD FV SS+ VWG GQ AYGAANAFLD LA R +GV A++V +G WA GM Sbjct: 2297 -RQDLDAFVLFSSMTGVWGNGGQGAYGAANAFLDALAEHRRAQGVPALAVAWGSWADGGM 2355 Query: 1367 ADAESRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRA-- 1423 AD + L +RGVR ++ A++ + + G VA +DW RF+P + G R Sbjct: 2356 ADGAAGDHLRRRGVRAIAALPAISVLHGALTHGETSMTVADVDWERFVPAF--VGTRPCP 2413 Query: 1424 -FLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RV 1481 L E+ LV++L A ++ ++ + +R A V Sbjct: 2414 LLLGVPEAREALEARARAAQSPEVPVSALVQRLLGATPGEQGRILLDLVREQAATVLGHT 2473 Query: 1482 DADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLG 1541 + F + G DSL AVELR R+ G +P TLV DHP + A +L E+LG Sbjct: 2474 GKGAFEADRTFRETGFDSLTAVELRHRLNTATGLRLPTTLVFDHPTPTALARHLGEELLG 2533 Query: 1542 L-GEQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR- 1598 G +T QA T A D+P+A+V +SCR PG PE WELL+ G DA+ P DR Sbjct: 2534 RHGLETAAAQA-TAAAAADEPLAIVGMSCRLPGGVQSPEDLWELLSSGRDAMSGFPTDRG 2592 Query: 1599 WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEG 1658 WDID YDPDPD PGKTY+R FGISPREA+ ++PQQRL+LET WE Sbjct: 2593 WDIDALYDPDPDRPGKTYSREGGFIQGADRFDAGLFGISPREALAMDPQQRLLLETAWEA 2652 Query: 1659 LERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFAL 1718 ERAG A + +R SRTGVF G +YA+ L + ++IE + +TG A + +SGR+++ Sbjct: 2653 FERAGIALASVRASRTGVFIGTNGQDYANGLR-NAPEEIEGYALTGKAASVVSGRISYTF 2711 Query: 1719 GFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSP 1778 G EGPAV VDTACSS+LVA+H A QAL+SG+C +AL GGV V+ +P V SR R LSP Sbjct: 2712 GLEGPAVTVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMTTPDLFVEFSRQRGLSP 2771 Query: 1779 VGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPN 1838 GRCK F A ADG EG G+L+++RLSDA R+G +V A++ S+VNQDGAS+GLT PN Sbjct: 2772 DGRCKAFAAGADGTGWGEGVGLLLVERLSDARRNGHQVLALVRGSAVNQDGASNGLTAPN 2831 Query: 1839 GGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMG 1898 G +QQR+I LA AGL+ ADVD +EAHGTGT LGDPIE Q P+ +G Sbjct: 2832 GPSQQRVIRQALASAGLTPADVDAVEAHGTGTRLGDPIEAQALLATYGQEHSDDRPVWLG 2891 Query: 1899 SVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQ 1958 SVK+NIGHT++A+G AG+IK+VL+++HGVLPQ+LH + P+ H+ W A VR++ EPV W Sbjct: 2892 SVKSNIGHTQAAAGVAGVIKMVLAMRHGVLPQTLHVDEPTAHVDWSAGAVRLLTEPVQWP 2951 Query: 1959 TNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSA 2018 RRA VSSFG GTNAH ++EEAP P LSA Sbjct: 2952 GTTGPRRAAVSSFGIGGTNAHTIIEEAPAAAAAEPAREHRPV----------PVPWVLSA 3001 Query: 2019 RSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXX 2078 +S AL A R AT + D ++ RS E+RAA++ Sbjct: 3002 KSEVALRAQAERL--LAFATDDVSPVDAGFSSATTRSALEHRAAVIGSDPAELRAGLEAL 3059 Query: 2079 XXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAEAVADM 2137 A VV G +LF+GQGSQ GM REL+ PVFA + CA Sbjct: 3060 AAGEPAANVVAGRAHSADKVGFLFSGQGSQRLGMGRELYAAYPVFAAAYDEVCA------ 3113 Query: 2138 LPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYA 2197 LLD D ET L T QPALFAVE+ L RL +SW I PD V GHSVG+ A Sbjct: 3114 ----LLDATVDVDAET---LHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIA 3166 Query: 2198 AACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNG 2257 AA VAGV SL+D A+L++ R + +LP GG MVAV A E + R + A NG Sbjct: 3167 AAHVAGVLSLEDAAKLVSARAALMKALPAGGVMVAV--QAAEDEMLPHLIDRAGIAAING 3224 Query: 2258 P-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXP 2316 P + V+SG + + I E F +G + + L SHAFHS L+DP+L+ P Sbjct: 3225 PRSVVISGAEDAVTAIAEVFAAQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSEP 3284 Query: 2317 TLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG 2376 +P+V N TG + TP +YW RH R+ V+FA+ V T+ LG + +EIGP VL+ Sbjct: 3285 WIPVVSNLTGRLTESYTP---EYWVRHVREAVRFADGVLTLHELGVTTFVEIGPGGVLS- 3340 Query: 2377 AAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPT 2436 A VQ + + +LR + + + A A +V G D+ A RR VELPT Sbjct: 3341 ALVQGCLDDGTDIVTIPALRADRPEPQALTTAYAQLHVSGAEVDWHAFFPGARR-VELPT 3399 Query: 2437 YPFQRRRFWPKASSI-----AVDGGTAASGILGSGKDLA-SGDTIYTSRLSVKSQPWLAD 2490 Y FQR R+W A + AV G A +LG+ LA S + T RLS + PWL D Sbjct: 3400 YAFQRERYWLDAPASAGDMRAVGQGEAGHPLLGAAVPLADSVGHLLTGRLSKHTHPWLVD 3459 Query: 2491 HVIYGTVVVPGATYAAMALAAVGTPA--RLKDVFFYEPIILPEKASREVQLTLHPADGGS 2548 H + G ++PG + +A+ A L+++ P+++PE+ +Q+ + DG Sbjct: 3460 HAVSGVALLPGTAFVELAITAADAVGCDLLEELTLETPLLVPERGGVALQVHVGADDGSG 3519 Query: 2549 VLSFQIHSR-PYGERGAD-------WSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLE 2600 +HS+ G+ A W +A G + A P + PV E Sbjct: 3520 RRPLTVHSQIDDGDAYAHEDDSERAWVRHASGVLTVATGGPVDGSLTAWPPVG-----AE 3574 Query: 2601 RMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI-LVGAELAEQLGSEPMHPVL 2659 + ++ A + L +GP + G L++ W + ++ L GAE + G+ +HP L Sbjct: 3575 PVDVDGFYDRLAGMALDYGPVFQG-LRAAWRSGDDFFAEVELPGAERTD-AGAYGLHPAL 3632 Query: 2660 MDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQ 2719 D E G + LP + V LA + S + T Sbjct: 3633 FD---AALHTVWLGAVEPEAGTGNGLLPFAWSGVRLAAAGASDLRVKV----SRAGTGTS 3685 Query: 2720 VFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAV 2779 L D G + + T++ P + L G G D ++ L W V P + D Sbjct: 3686 TVSLVLADGTGGPVAEVDSLTLRPVPADQLRAGSGSDDA--VFGLKWTPVSLPSAPDG-- 3741 Query: 2780 GTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAG 2822 I +++LAA P D D + + G G Sbjct: 3742 --MRIETYEDLAALRATDPPADTEADAAAAADAVVVPCPTGTG 3782 Score = 860 bits (2222), Expect = 0.0 Identities = 676/1985 (34%), Positives = 939/1985 (47%), Gaps = 184/1985 (9%) Query: 1034 AASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQ 1093 AA+A + VV G GA R + V H L L + E + LVTR G Sbjct: 3766 AAAAADAVVVPCPTGTGADLATR-VREVTHAVL----ELVQWWLAEERPGRLVLVTRGGD 3820 Query: 1094 RVTDTDTVVPEQSCLWGFGRAAALELP------------HIWGGLADLSGAD-TEWPRLI 1140 QS + G R+A E P H G SG D + R++ Sbjct: 3821 LA---------QSAVCGLVRSAQTENPDRIVLVETSSDAHAGAG----SGVDDADLARVL 3867 Query: 1141 ARITSPRDGEDQIALRGD-AVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVA 1199 + + GE Q A+ D V PRLVR ++ LP T L+TG G +G A Sbjct: 3868 PGLIA--SGEPQAAVHADDEVRVPRLVRVAVPDAEPELPGLGSGTVLLTGASGGLGGLFA 3925 Query: 1200 GYL-ASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVA 1258 +L A HG ++L SRR DV DVAD V L+ A Sbjct: 3926 RHLVAEHGVRSLLLVSRRGGDAPGAAELTADLTAQGADVTWAACDVADRAAVRALL---A 3982 Query: 1259 AELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVST 1318 L+ I+H AG + + L +D VF KV A +L + +L DL FV Sbjct: 3983 GPGQSLSAIIHTAGVLDDGIIGSLTPERLDAVFRPKVDAALNLHDLAGELSGDLSAFVLF 4042 Query: 1319 SSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-------AGMADAES 1371 SS+A G GQ Y AAN FLD LA R G A S+ +G WA G D Sbjct: 4043 SSVAGTLGTPGQANYAAANTFLDALAEHRRAAGQRATSLAWGLWAQDSESAMTGSLDHTD 4102 Query: 1372 RARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAG--RRAFLSELE 1429 R+++ G+ + ++ L + D + VVA PL G + L Sbjct: 4103 LTRIQRMGLAAIPSSDGLR-LFDAALALDRAVVA--------PLRLDLGGLQGTVPPVLR 4153 Query: 1430 SELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRD 1488 L ++L +R+ ++ + +R VA V A + Sbjct: 4154 GLRGTVRGTARRTAQTAPKGSLGQRLAGLAEAEREQVVLDLVRTEVAAVLGHAGAQSVGA 4213 Query: 1489 EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNV 1548 + F D+G DSL AVELR R+ VG +P TL+ D+P A +L E G T V Sbjct: 4214 DDSFKDIGFDSLTAVELRNRLNSAVGMRLPATLIFDYPNPLTLAHFLTGEAAGGEAATAV 4273 Query: 1549 RQA-STVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDIDEFY 1605 ST T D+PIA+V ++CR+PG PE W+L+ G DA+ PE R WD+++ Y Sbjct: 4274 PTTLSTATGTADEPIAIVGMACRYPGGVQSPEDLWQLVFSGRDAVSGFPEGRGWDVEQLY 4333 Query: 1606 DPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYA 1665 DP+PD G +YTR EFFGISPREA+ ++PQQRL+LET WE ERAG Sbjct: 4334 DPNPDQWGTSYTREGGFLHDAADFDAEFFGISPREALAMDPQQRLLLETSWEAFERAGID 4393 Query: 1666 PSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAV 1725 P+ +RGSRTGVF GV ++Y + S +E + + G+A + SGRV++ G EGPAV Sbjct: 4394 PATVRGSRTGVFAGVMYHDYGGRVHT-SPPGLEGYLVNGSAGSIASGRVSYTFGLEGPAV 4452 Query: 1726 AVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTF 1785 VDTACSS+LVA+H A QAL+SG+C +AL GGV V+ P V SR R LS GRCK F Sbjct: 4453 TVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMAGPSVFVEFSRQRGLSADGRCKAF 4512 Query: 1786 DASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRL 1845 A ADG +EG G+L+++RLSDA R+G +V AV+ ++VNQDGAS+GLT PNG +QQR+ Sbjct: 4513 GAGADGTGWAEGVGMLLVERLSDARRNGHKVLAVVRGTAVNQDGASNGLTAPNGPSQQRV 4572 Query: 1846 IEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIG 1905 I LA AGLS +VD +EAHGTGT LGDPIE Q PL +GS+K+NIG Sbjct: 4573 IRQALANAGLSSDEVDAVEAHGTGTRLGDPIEAQALIATYGQERSEDRPLWLGSLKSNIG 4632 Query: 1906 HTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRR 1965 H+++A+G G+IK+V+++QHGVLPQ+LH + P+PH+ W A V+++ E V W + RR Sbjct: 4633 HSQAAAGVGGVIKMVMAMQHGVLPQTLHVDEPTPHVDWSAGAVQLLTEAVEWPASDGPRR 4692 Query: 1966 AGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTD-DSPQVLALSARSPEAL 2024 A VSSFG +GTNAHV+VE+A GT P LSA+S AL Sbjct: 4693 AAVSSFGVSGTNAHVIVEQAATS------------EVTARGTAVAGPVPWVLSAKSDAAL 4740 Query: 2025 VELARRYDDWLSAT----PGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXX 2080 E A R +L A G+ DV ++ R+ E RAA+V + + Sbjct: 4741 REQAGRLLSFLDAEGVGGAGVRPEDVAYSLATSRAVLECRAAVVGEELGEFRQGLEGIVS 4800 Query: 2081 XXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAEAVADMLP 2139 P G G V +LF+GQGSQ GM REL+ PVFA + CA Sbjct: 4801 GAAPVGGAVGGRV-----GFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCA-------- 4847 Query: 2140 RPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAA 2199 LLD D ET L T QPALFAVE+ L RL +SW I PD V GHSVG+ AAA Sbjct: 4848 --LLDATVDVDAET---LHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAA 4902 Query: 2200 CVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP- 2258 VAGV SL+D A+L++ R + +LP GG MVA+ A E + V + A NGP Sbjct: 4903 HVAGVLSLEDAAKLVSARAALMQALPAGGAMVAI--QATEAEVLPHLTHGVGLAAINGPR 4960 Query: 2259 NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTL 2318 + VLSG + + +I E F +G + + L SHAFHS L+DP+L+ P + Sbjct: 4961 SVVLSGSEDAVLDIAEVFAQQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSEPRI 5020 Query: 2319 PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAA 2378 P+V N TG + P +YW RH R+ V+FA+ + T+ LG ++ +EIGP VL+ A Sbjct: 5021 PVVSNLTGRLAEVYIP---EYWVRHVREAVRFADGLHTLHELGVTMFVEIGPGGVLS-AL 5076 Query: 2379 VQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYP 2438 VQ + V +LR + + A+ + G P++ A+ RR V+LPTY Sbjct: 5077 VQGCLDDGTHIVTVPALRADRPEPYALVTAVGQLHTHGISPEWQALFPGARR-VDLPTYA 5135 Query: 2439 FQRRRFW---PKASS--IAVDGGTAASGILGSGKDLASGD-TIYTSRLSVKSQPWLADHV 2492 FQR R+W P+AS A G A +LG+ A D + T LS+ + PWLADH Sbjct: 5136 FQRERYWLDAPQASGDVRAAGLGAADHPLLGAAIATADSDGAVLTGLLSLGTHPWLADHA 5195 Query: 2493 IYGTVVVPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHPADGGSVL 2550 + G V++PG + +A+ A ++D+ P+++PE+ +Q+ + P D Sbjct: 5196 VNGIVLLPGTAFVELAIRAGDETGCGWIEDLTLELPLVVPERGGVTLQVAVGPEDESGRR 5255 Query: 2551 SFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLFET 2610 +HSR W +A G + +A + P AA P E + +E Sbjct: 5256 QLSVHSR---VDDRSWLRHATGVLSSAEA-PSAAKLGAWPPAG-----AEAVDLTAFYEG 5306 Query: 2611 FADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXX 2670 A L +GP + G L+S+W + ++ + E A + + +HP L+D Sbjct: 5307 MAAAGLDYGPVFQG-LRSVWRDGDDVFAEVELPDESAAEAAAFALHPALLDAALHALAAG 5365 Query: 2671 XXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGG 2730 LP + V + + R + R+A S T L D G Sbjct: 5366 GLVSLDDSPA-----LPFAWSGVVV--QAAGAAMVRVKLSRTATGSVT----LAVADGAG 5414 Query: 2731 RALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDEL 2790 + + +++ A E L +GGD L+ L W PSA DA+ +A FD L Sbjct: 5415 DPVASVESLSLRAASAEQLPGAVGGDQ---LFGLEWTRF-TLPSATDALMIETVADFDAL 5470 Query: 2791 AAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXX 2850 + D+ V+ V A G+G Sbjct: 5471 RES-------EGTPDVVVVPVVPCPA---GSG---------------------------- 5492 Query: 2851 XITNLLSAVHAAQGPSVKLPGGLWIVTEH-GVACESGEPVDPVQAALWGFGRTTINEEPA 2909 VH+ + L W+ E G P D AA+WG R+ +E P Sbjct: 5493 --RETADRVHSTTSEVLALV-QWWLAEERAGRLALVTRPGDLAHAAVWGLVRSAQSENPD 5549 Query: 2910 LHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGD 2969 LV+ + + EAV EP+ AVR G++ RL+ RS T D Sbjct: 5550 -RIVLVEAEETDEAVRVLPAAL---ASGEPQFAVRDGEVFVPRLVKATRSATGTATGTPD 5605 Query: 2970 FVLAP 2974 F + P Sbjct: 5606 FGVGP 5610 Score = 688 bits (1775), Expect = 0.0 Identities = 461/1153 (39%), Positives = 616/1153 (53%), Gaps = 73/1153 (6%) Query: 1339 FLDGLAWRLRERGV-TAVSVNFGPWAAGMADAESRAR-LEQRGVRTLSPAEALAGMADVV 1396 F DG+A RL E+GV T + + G A MA A + + L +RT P EA A +A V Sbjct: 808 FADGVA-RLDEQGVRTYLELGPGGVLASMARAGADSESLFVPALRTRRP-EAQALLAAVA 865 Query: 1397 AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXL----- 1451 + V GV + DW + A R+ L E Sbjct: 866 SLHVHGV--EPDWDALFGGGRGARRKVALPTYAFERQRYWLDGDTTSPVATTGWAPVAPQ 923 Query: 1452 ---VEQLTKAPV------------QQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDL 1495 + + APV +R + + +R +A V +A ++ E F DL Sbjct: 924 PDAIAETDSAPVGALGRRLAGLAESERDEAVLDMVRAHIAAVLGHAEARQVETEWTFKDL 983 Query: 1496 GMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVT 1555 G DSL +VELR ++ + G +P L+ DHP + A +L + LG G+ A Sbjct: 984 GFDSLSSVELRNQLSEATGLRLPSGLLFDHPTPAALARHLAAQSLGGGDA--AAAAPATV 1041 Query: 1556 ARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPG 1613 A +PIA+VA+SCR P G PE W LLA G D I P DR WD++ YDP+P TPG Sbjct: 1042 ADPHEPIAIVAMSCRLPGGVSSPEDLWRLLASGGDGISGFPTDRGWDVETLYDPEPGTPG 1101 Query: 1614 KTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSR 1673 K+ TR FFGISPREA I+PQQRL+LET WE ERAG P+ LRGSR Sbjct: 1102 KSSTRHGGFLHEAAEFDAGFFGISPREAAAIDPQQRLVLETAWEAFERAGIDPATLRGSR 1161 Query: 1674 TGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSS 1733 GVF G A +Y L E D +E + +TG + SGRVA++ G EGPAV VDTACSS Sbjct: 1162 AGVFIGATAQDYGPRLH-EPADGVEGYLLTGTTTSVASGRVAYSFGLEGPAVTVDTACSS 1220 Query: 1734 ALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYV 1793 +LVA+H A Q+L+SG+C +ALAGGV V+ +P V SR R LS GRCK F A ADG Sbjct: 1221 SLVALHLAVQSLRSGECTMALAGGVTVMSTPGMFVEFSRQRGLSADGRCKAFAAGADGTG 1280 Query: 1794 RSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARA 1853 +EG G+L+++RLSDA R+G +V AV+ S+VNQDGAS+GLT PNG +QQR++ LA A Sbjct: 1281 WAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRQALAAA 1340 Query: 1854 GLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGA 1913 GL+ ADVD +EAHGTGT LGDPIE + PL +GS+K+NIGHT++A+G Sbjct: 1341 GLAPADVDAVEAHGTGTLLGDPIEAEALIAAYGQGRDGDRPLWLGSLKSNIGHTQAAAGV 1400 Query: 1914 AGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGF 1973 AG+IK+V++++HGVLP++LH + P+PH+ W A VR++ E V W RRA VSSFG Sbjct: 1401 AGVIKMVMAMRHGVLPRTLHVDEPTPHVDWSASGVRLLTEAVEWPARDLPRRAAVSSFGI 1460 Query: 1974 TGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTD-DSPQVLALSARSPEALVELARRYD 2032 +GTNAHV+VE+A GT P +SA+S AL E A R Sbjct: 1461 SGTNAHVIVEQAATS------------EEPARGTAVAGPVPWVVSAKSDVALREQAGRLL 1508 Query: 2033 DWLSAT----PGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVV 2088 +L A G+ DV + R+ E RAA+V + + A V Sbjct: 1509 SFLDAEGVGGAGVRPEDVALSLATSRAVLERRAAVVGGDLAELRQGLEALASGASGAAPV 1568 Query: 2089 RGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAEAVADMLPRPLLDVLF 2147 G R +LF+GQGSQ GM REL+ PVFA + CA LD Sbjct: 1569 GGAVGGR--VGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCA----------FLDAPV 1616 Query: 2148 ATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSL 2207 D E L T QPALFAVE+ L RL +SW I PD V GHSVG+ AAA VAGV SL Sbjct: 1617 DVDSEE---LNQTGTTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLSL 1673 Query: 2208 DDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-NTVLSGPG 2266 +D A+L++ R + +LP+GG MVAV A + V + + V + A NGP + V+SG Sbjct: 1674 EDAAKLVSARAALMQALPDGGAMVAVQATEDEVLRHLTD--GVGIAAVNGPRSVVVSGAE 1731 Query: 2267 EDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTG 2326 + + + E F G + + L SHAFHS L+DP+L+ +P+V N TG Sbjct: 1732 DAVTAVGEIFAGRGRKTSRLKVSHAFHSPLMDPMLEEFAAVVRGLTFSESRIPVVSNLTG 1791 Query: 2327 AVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHM 2386 + TP +YW RH R+ V+FA+ + T+ LG + +E+GP VL+ A + + Sbjct: 1792 RLAEVYTP---EYWVRHVREAVRFADGIETLGELGVTTFVEVGPGGVLSALAQGCFDDGT 1848 Query: 2387 AAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWP 2446 V LR + + A+ + G PD+ + RR V+LPTY FQR R+W Sbjct: 1849 DIV-TVPVLRADRPEPYALVTAIGRLHTHGISPDWQVLFPGARR-VDLPTYAFQRERYWL 1906 Query: 2447 KASSIAVDGGTAA 2459 A A G A Sbjct: 1907 DAPRAATAGAPDA 1919 Score = 620 bits (1600), Expect = e-174 Identities = 377/918 (41%), Positives = 516/918 (56%), Gaps = 50/918 (5%) Query: 3 SAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPD 60 +A+ PI AI+G A R+PG S E+ W L+ GR+A+S P+ R WD+E+ +DP+ Sbjct: 4283 TADEPI------AIVGMACRYPGGVQSPEDLWQLVFSGRDAVSGFPEGRGWDVEQLYDPN 4336 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P G TR GF+ D FDA FFG+S RE MDPQ R+L+ET+W A E +GI P + Sbjct: 4337 PDQWGTSYTREGGFLHDAADFDAEFFGISPREALAMDPQQRLLLETSWEAFERAGIDPAT 4396 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 + S TGVF G+ HDY G + P +E Y+ G++ + A+GR+SY GL+GPAV V Sbjct: 4397 VRGSRTGVFAGVMYHDYGGRV--HTSPPGLEGYLVNGSAGSIASGRVSYTFGLEGPAVTV 4454 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVA+H A QALR EC +AL GG V+ P+ + FS L+ DGRCK F A Sbjct: 4455 DTACSSSLVALHLAAQALRSGECSMALVGGVTVMAGPSVFVEFSRQRGLSADGRCKAFGA 4514 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 ADG EG G+++V+RL DA R+G ++ AV+RG+A+NQDGAS GLT PNG +QQRVI Sbjct: 4515 GADGTGWAEGVGMLLVERLSDARRNGHKVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIR 4574 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 AL AGL +V +EAHGTGT LGDPIEAQA G R+ + PL +GS K+NIGH Sbjct: 4575 QALANAGLSSDEVDAVEAHGTGTRLGDPIEAQALIATYGQERSEDRPLWLGSLKSNIGHS 4634 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 + +++ LP+ L+ + P+PH+ W ++++ E V W + PR A Sbjct: 4635 QAAAGVGGVIKMVMAMQHGVLPQTLHVDEPTPHVDWSAGAVQLLTEAVEWPASDGPRRAA 4694 Query: 421 VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL 480 VSSFG +GTNAHVI+E+A A V P + LSA++ AL AG +L Sbjct: 4695 VSSFGVSGTNAHVIVEQAATSEVTARGTAVAGPVPW---VLSAKSDAALREQAGRLLSFL 4751 Query: 481 RAH----PQARLADVSHTAGTARAHLEQRAALVVNS-RESAIELLGALADDRPAPGLVRG 535 A R DV+++ T+RA LE RAA+V E L G ++ P G V G Sbjct: 4752 DAEGVGGAGVRPEDVAYSLATSRAVLECRAAVVGEELGEFRQGLEGIVSGAAPVGGAVGG 4811 Query: 536 ESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRK-CAEAVADILEKPLLDVIFDA 594 + +LF+GQGSQ GM REL+ PVFA + CA LLD D Sbjct: 4812 ------RVGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCA----------LLDATVDV 4855 Query: 595 DELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFD 654 D L T QPALFAVE+ L RL +SWG PD V GHSVG+ +AA VAGV Sbjct: 4856 D------AETLHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLS 4909 Query: 655 VEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPA 714 +ED A+L++ R L +LPAGG M A+ AE L + +AA NG +V+ + Sbjct: 4910 LEDAAKLVSARAALMQALPAGGAMVAI--QATEAEVLPHLTHGVGLAAINGPRSVVLSGS 4967 Query: 715 KDLESAVATLVA-DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRT 773 +D +A + A G + L SHAFHS L+DP+L++F + L + EP+ ++ N T Sbjct: 4968 EDAVLDIAEVFAQQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSEPRIPVVSNLT 5027 Query: 774 GSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDP 833 G + YW RH R+ V FA + TL ++ + +EIGP VL+A D Sbjct: 5028 GRL---AEVYIPEYWVRHVREAVRFADGLHTLHELGVTMFVEIGPGGVLSALVQGCL-DD 5083 Query: 834 ATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFW 893 T + +LR + + AV + G P+++A P AR++DLPTY F+ ++W Sbjct: 5084 GTHIVTVPALRADRPEPYALVTAVGQLHTHGISPEWQAL-FPGARRVDLPTYAFQRERYW 5142 Query: 894 FSDNRAIDRDTQTASAGS 911 +A D + A G+ Sbjct: 5143 LDAPQA-SGDVRAAGLGA 5159 Score = 612 bits (1577), Expect = e-172 Identities = 383/964 (39%), Positives = 526/964 (54%), Gaps = 53/964 (5%) Query: 15 AIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAGF 74 A+IG A R PGAA +W LL +G +AI+DVP DRWD D S P + RR GF Sbjct: 25 AVIGLACRLPGAADPAAFWRLLSEGADAITDVPPDRWDGAVV--ADASAPDRTGIRRGGF 82 Query: 75 VDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLAT 134 +D + FDA FFG+S +E MDPQ R+++E AW A+E + + +L ++ TGVFVG Sbjct: 83 LDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALEDAHVRAATLRSTRTGVFVGAMW 142 Query: 135 HDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQA 194 DY + I + G + A R+SY LGL GP++ VD+ SSSLV++H A Sbjct: 143 DDYATL-HHRSGLTAISPHTVTGLHRSIIANRVSYFLGLNGPSLTVDSGQSSSLVSVHLA 201 Query: 195 CQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVV 254 C++LR E +ALAGG N+ + P + + + L+PDGRC TFDA A+GYVRGEG G+V Sbjct: 202 CESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDGRCFTFDARANGYVRGEGGGIV 261 Query: 255 VVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVG 314 V+K L AV DGD + VIRGSA+N DG GLTVP Q++V+ A +RAG+ PADVG Sbjct: 262 VLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQSGQEQVLRLAYERAGVNPADVG 321 Query: 315 YLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXXX 374 Y+E HGTGT +GDPIEA A G VLG GR P PL +GSAKTN+GHLE Sbjct: 322 YVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSAKTNVGHLEGAAGITGLLKAVL 381 Query: 375 XLENETLPKHLNFETPSPHIPWERLPIEVVRETVPW-QRNGKPRIAGVSSFGFAGTNAHV 433 L + LP LNF TP+P IP +RL + V E W +G+P +AGVSSFG GTN H+ Sbjct: 382 SLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAEDGRPLLAGVSSFGMGGTNCHI 441 Query: 434 ILEEAPAV--GTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQA----R 487 +L AV G AT P + PLSA+T L A L AH +A Sbjct: 442 VLASGAAVEAGEGATAGGGAAP---TFWPLSAKTASGLRAQAAA----LLAHTEAPLGLA 494 Query: 488 LADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLF 547 L DV + T R E RA +V R+ + L L+ L G + + A+LF Sbjct: 495 LPDVGWSLATGRTAFEHRAVVVGEVRDDFLRALRELSTGGIDAALTTGRAGPRGELAFLF 554 Query: 548 TGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIF------DADELDGDT 601 +GQGSQ GM REL ++ P FA + + + +L +PL +V+F +A ELD Sbjct: 555 SGQGSQRAGMGRELAESVPAFASALDEVCAHLDPLLPRPLREVMFAPVGTGEAAELD--- 611 Query: 602 ESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARL 661 T Y Q +LFAVE+ L RL +SW PDV++GHS+G+ +AA VAGV + D L Sbjct: 612 -----QTLYTQTSLFAVEVALFRLLESWDITPDVLMGHSIGELAAAHVAGVLSLADACAL 666 Query: 662 IAERGRLFGSLPAGGRMAAVFTAPERAE-RLTDEYPSLSVAAYNGANTVLSGPAKDLESA 720 +A RGRL +LPAGG M AV A + R+ + +S+AA NG ++V+ +DL + Sbjct: 667 VAARGRLMQALPAGGAMIAVQAAEDEVRARIGERTDRVSIAALNGPDSVVVSGDEDLATE 726 Query: 721 VA-TLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 +A A G + L SHAFHS ++P+L +F + A+ L + P+ ++ N TG Sbjct: 727 IADAFAALGRKTSRLRVSHAFHSPHMEPMLAEFRNVAEGLTFHAPRIPIVSNVTGRLSEE 786 Query: 780 STRLDG---AYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATT 836 + +G AYW RH R+ V FA V L + R LE+GP VL + A A + Sbjct: 787 PSGYEGCTAAYWVRHVREAVRFADGVARLDEQGVRTYLELGPGGVLASMARAGADSESLF 846 Query: 837 PQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAF---RQPDARKLDLPTYPFEHRQFW 893 L + RP + + + AVA+ + G PD+ A + RK+ LPTY FE +++W Sbjct: 847 VPALRTRRP---EAQALLAAVASLHVHGVEPDWDALFGGGRGARRKVALPTYAFERQRYW 903 Query: 894 FSDNRAIDRDT----QTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLN 949 +D DT T V P + A+ + + L + G E+ VL+ Sbjct: 904 ------LDGDTTSPVATTGWAPVAP-QPDAIAETDSAPVGALGRRLAGLAESERDEAVLD 956 Query: 950 KLAA 953 + A Sbjct: 957 MVRA 960 Score = 595 bits (1535), Expect = e-167 Identities = 368/905 (40%), Positives = 499/905 (55%), Gaps = 28/905 (3%) Query: 1553 TVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTP 1612 + +A + D IAV+ ++CR PGA DP +FW LL+ G DAI +VP DRWD D P Sbjct: 15 SASADSADGIAVIGLACRLPGAADPAAFWRLLSEGADAITDVPPDRWD--GAVVADASAP 72 Query: 1613 GKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGS 1672 +T R FFG+SP+EA ++PQQRL+LE WE LE A + LR + Sbjct: 73 DRTGIRRGGFLDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALEDAHVRAATLRST 132 Query: 1673 RTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACS 1732 RTGVF G ++YA L + I PH +TG + I+ RV++ LG GP++ VD+ S Sbjct: 133 RTGVFVGAMWDDYATLHHRSGLTAISPHTVTGLHRSIIANRVSYFLGLNGPSLTVDSGQS 192 Query: 1733 SALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGY 1792 S+LV+VH AC++L+ G+ +ALAGGVN+ + P + + A++ LSP GRC TFDA A+GY Sbjct: 193 SSLVSVHLACESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDGRCFTFDARANGY 252 Query: 1793 VRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLAR 1852 VR EG G++VLK L+ AV DGD V VI S+VN DG GLTVP Q++++ R Sbjct: 253 VRGEGGGIVVLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQSGQEQVLRLAYER 312 Query: 1853 AGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASG 1912 AG++ ADV Y+E HGTGT +GDPIE PL +GS KTN+GH E A+G Sbjct: 313 AGVNPADVGYVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSAKTNVGHLEGAAG 372 Query: 1913 AAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT-NGRVRRAGVSSF 1971 GL+K VLSL H LP SL+F P+P IP D L +RV E W +GR AGVSSF Sbjct: 373 ITGLLKAVLSLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAEDGRPLLAGVSSF 432 Query: 1972 GFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRY 2031 G GTN H+++ G +P LSA++ L A Sbjct: 433 GMGGTNCHIVLASG---------AAVEAGEGATAGGGAAPTFWPLSAKTASGLRAQAAAL 483 Query: 2032 DDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGE 2091 A GL + DV + GR+ FE+RA +V + A + G Sbjct: 484 LAHTEAPLGLALPDVGWSLATGRTAFEHRAVVVGEVRDDFLRALRELSTGGIDAALTTGR 543 Query: 2092 HVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFAT-- 2149 R A+LF+GQGSQ GM REL ++ P FA + + + +LPRPL +V+FA Sbjct: 544 AGPRGELAFLFSGQGSQRAGMGRELAESVPAFASALDEVCAHLDPLLPRPLREVMFAPVG 603 Query: 2150 DRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDD 2209 E A+L Q T + Q +LFAVE+ L RL +SW I PDV++GHS+G+ AAA VAGV SL D Sbjct: 604 TGEAAELDQ-TLYTQTSLFAVEVALFRLLESWDITPDVLMGHSIGELAAAHVAGVLSLAD 662 Query: 2210 GARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGE-FPRVSVGAYNGPNTVLSGPGED 2268 L+A RGR+ +LP GG M+AV A + V GE RVS+ A NGP++V+ ED Sbjct: 663 ACALVAARGRLMQALPAGGAMIAVQAAEDEVRARIGERTDRVSIAALNGPDSVVVSGDED 722 Query: 2269 L-EEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGA 2327 L EI + F G + + L SHAFHS ++P+L P +P+V N TG Sbjct: 723 LATEIADAFAALGRKTSRLRVSHAFHSPHMEPMLAEFRNVAEGLTFHAPRIPIVSNVTGR 782 Query: 2328 VL---TGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTG-AAVQVWP 2383 + +G A YW RH R+ V+FA+ V + G +E+GP VL A Sbjct: 783 LSEEPSGYEGCTAAYWVRHVREAVRFADGVARLDEQGVRTYLELGPGGVLASMARAGADS 842 Query: 2384 EHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVH---RQPRRPVELPTYPFQ 2440 E + P +LR + + + A+AS +V G PD+ A+ R RR V LPTY F+ Sbjct: 843 ESLFVP----ALRTRRPEAQALLAAVASLHVHGVEPDWDALFGGGRGARRKVALPTYAFE 898 Query: 2441 RRRFW 2445 R+R+W Sbjct: 899 RQRYW 903 Score = 148 bits (373), Expect = 2e-32 Identities = 140/470 (29%), Positives = 206/470 (43%), Gaps = 37/470 (7%) Query: 1087 LVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSP 1146 LVTR G + +WG R+A E P L + D L A + S Sbjct: 5524 LVTRPGDLA---------HAAVWGLVRSAQSENPDRIV-LVEAEETDEAVRVLPAALAS- 5572 Query: 1147 RDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT--YLVTGGLGAIGLEVAGYL-A 1203 GE Q A+R V+ PRLV+ T + T + L+TG GA+G VA +L A Sbjct: 5573 --GEPQFAVRDGEVFVPRLVKATRSATGTATGTPDFGVGPVLLTGASGALGGLVARHLVA 5630 Query: 1204 SHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPP 1263 HG ++L SRR + +VR DVAD V+ ++ + + Sbjct: 5631 EHGVRSLLLLSRRGAEAPGAVELEAELAAWGAEVRWAACDVADREAVSGMLNGLGEQ--S 5688 Query: 1264 LAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIAS 1323 L+ +VH AG +G ++ L + VF KV +L E D+ L FV SS+A Sbjct: 5689 LSAVVHTAGVLGDGIVASLTPERMREVFRPKVDAVLNLHECTRDM--GLAAFVVFSSVAG 5746 Query: 1324 VWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW------AAGMADAESRARLEQ 1377 + G GQ +Y AAN+FLD + R G+ A+S+ +G W G+ +A+ RAR+ + Sbjct: 5747 MVGSAGQASYAAANSFLDAFSAHRRREGLPAISLAWGVWEQSGAMTDGLVEAD-RARMAR 5805 Query: 1378 RGVRTLSPAEALAGMADVVAGPVQGVVA--KIDWSRFLPLYQQAGRRAFLSELESELXXX 1435 GV L P E L + D + V+A +ID RA + + Sbjct: 5806 SGVLPLPPEEGLR-LFDAALASDEAVLAPVRIDTGALRAGEAPPVLRALVPAAAAR---- 5860 Query: 1436 XXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADE-IRDEAGFFD 1494 L E+L + P +R+ + + +R VA +D +R E F D Sbjct: 5861 --RTARAAAAPSASSLAERLEEMPEAEREKTVLDLVRAEVAAGLGHASDRTVRPEHAFQD 5918 Query: 1495 LGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGE 1544 LG DSL AVELR R+ + G +P TLV DHP + A ++ + G E Sbjct: 5919 LGFDSLTAVELRNRLNKATGLRLPATLVFDHPTPALLARHVFMAAAGAAE 5968 Score = 142 bits (357), Expect = 1e-30 Identities = 114/369 (30%), Positives = 160/369 (43%), Gaps = 22/369 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G A +LA GA +VLTSRR PD + E ++ A D Sbjct: 2180 LVTGGTGALGGQVARWLAGAGAEHLVLTSRRGPDAPGAAELKAELEELGAQVTVVACDAA 2239 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASH-XXXX 3416 D +A+L R + H AGVLDD L+ + PER L PK A H Sbjct: 2240 DRDALAELFGRYIVN-----AVVHTAGVLDDGLVESLTPERLNHVLRPKVDAALHLHELT 2294 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQ Y ANA LD L RRAQG+ A + +G W GG Sbjct: 2295 RDRQDLDAFVLFSSMTGVWGNGGQGAYGAANAFLDALAEHRRAQGVPALAVAWGSWADGG 2354 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPI 3536 MA AA ++ +G+ + A+ L + +G TV +W+R RP Sbjct: 2355 MADG-AAGDHLRRRGVRAIAALPAISVLHGALTHGETSMTVADVDWERFVPAFVGTRPCP 2413 Query: 3537 LDLVLPSA--AGEATGD---------SELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA 3585 L L +P A A EA S L+++L+ ++ + + ++ + L Sbjct: 2414 LLLGVPEAREALEARARAAQSPEVPVSALVQRLLGATPGEQGRILLDLVREQAATVLGHT 2473 Query: 3586 SPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A A F + G DSL A+ELR+RL++ G + T VFD+PT LA +L +L Sbjct: 2474 GKGAFEADRTFRETGFDSLTAVELRHRLNTATG--LRLPTTLVFDHPTPTALARHLGEEL 2531 Query: 3644 PDAEAPETA 3652 ETA Sbjct: 2532 LGRHGLETA 2540 Score = 134 bits (338), Expect = 2e-28 Identities = 111/365 (30%), Positives = 161/365 (44%), Gaps = 20/365 (5%) Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TG GA+G A +L A+ G ++L SRR + ++ + A DV Sbjct: 5612 LLTGASGALGGLVARHLVAEHGVRSLLLLSRRGAEAPGAVELEAELAAWGAEVRWAACDV 5671 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D V+ +L + + L+ + H AGVL D ++++ PER R PK + Sbjct: 5672 ADREAVSGMLNGLGEQ--SLSAVVHTAGVLGDGIVASLTPERMREVFRPKVDAVLNLHEC 5729 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQA+YA AN+ LD A RR +GL A + +G W Q G Sbjct: 5730 TRDMGLAAFVVFSSVAGMVGSAGQASYAAANSFLDAFSAHRRREGLPAISLAWGVWEQSG 5789 Query: 3477 MASS---EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSAR 3533 + EA A + G++PL P L +A S +A + A G A Sbjct: 5790 AMTDGLVEADRARMARSGVLPLPPEEGLRLFDAALA--SDEAVLAPVRIDTGALRAGEA- 5846 Query: 3534 PPILDLVLPSAAGEAT-------GDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 PP+L ++P+AA T S L ++L E+P +R V + ++ EV L AS Sbjct: 5847 PPVLRALVPAAAARRTARAAAAPSASSLAERLEEMPEAEREKTVLDLVRAEVAAGLGHAS 5906 Query: 3587 PPAA--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLP 3644 F DLG DSL A+ELRNRL+ G + AT VFD+PT LA ++ Sbjct: 5907 DRTVRPEHAFQDLGFDSLTAVELRNRLNKATG--LRLPATLVFDHPTPALLARHVFMAAA 5964 Query: 3645 DAEAP 3649 A P Sbjct: 5965 GAAEP 5969 Score = 117 bits (292), Expect = 4e-23 Identities = 109/367 (29%), Positives = 150/367 (40%), Gaps = 25/367 (6%) Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TG G +G A +L A+ G ++L SRR D + + A DV Sbjct: 3912 LLTGASGGLGGLFARHLVAEHGVRSLLLVSRRGGDAPGAAELTADLTAQGADVTWAACDV 3971 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS--HXX 3414 D A V LLA L+ I H AGVLDD ++ + PER PK A H Sbjct: 3972 ADRAAVRALLA---GPGQSLSAIIHTAGVLDDGIIGSLTPERLDAVFRPKVDAALNLHDL 4028 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 PGQANYA AN LD L RRA G AT + +G W Q Sbjct: 4029 AGELSGDLSAFVLFSSVAGTLGTPGQANYAAANTFLDALAEHRRAAGQRATSLAWGLWAQ 4088 Query: 3475 GGMASSEAA-----TANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVL 3529 ++ + I GL + S L +A L+ + L Sbjct: 4089 DSESAMTGSLDHTDLTRIQRMGLAAIPSSDGLRLFDAALALDRAVVAPLRLD----LGGL 4144 Query: 3530 GSARPPILDLVLPSAAGEATGDSE------LLKQLMEIPIPQRAGFVTEFLQREVQNFLR 3583 PP+L + + G A ++ L ++L + +R V + ++ EV L Sbjct: 4145 QGTVPPVLRGLRGTVRGTARRTAQTAPKGSLGQRLAGLAEAEREQVVLDLVRTEVAAVLG 4204 Query: 3584 LASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG 3641 A + A F D+G DSL A+ELRNRL+S G + AT +FDYP LA +L G Sbjct: 4205 HAGAQSVGADDSFKDIGFDSLTAVELRNRLNSAVG--MRLPATLIFDYPNPLTLAHFLTG 4262 Query: 3642 QLPDAEA 3648 + EA Sbjct: 4263 EAAGGEA 4269 >tr|Q9X993|Q9X993_9ACTO Tax_Id=68242 (pimS1)SubName: Full=PimS1 protein; SubName: Full=Polyketide synthase;[Streptomyces natalensis] Length = 6797 Score = 1588 bits (4111), Expect = 0.0 Identities = 1104/2998 (36%), Positives = 1491/2998 (49%), Gaps = 165/2998 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ A RFPG S EE W LLRDG +A+S P++R WD++ + DP+ G R Sbjct: 37 AIVSMACRFPGGVRSPEELWELLRDGVDAVSSFPRNRGWDLDALYHSDPAHQGTSYAREG 96 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FD FFG+S RE MDPQ R+L+ETAW AVE +GI P SLA S TGVFVG Sbjct: 97 GFLHDAGEFDPGFFGISPREALAMDPQQRLLLETAWEAVERAGIDPESLAGSRTGVFVGT 156 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 Y A E+ ++ G + A+GRISY LGL+GPA+ VDTACSSSLVA+H Sbjct: 157 GHGGY--DAEGRRRADEVGGHLLTGNHISIASGRISYVLGLEGPALTVDTACSSSLVALH 214 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A ALR +EC +AL GGA V+ TP + FS LAPDGRCK F AAADG EG G Sbjct: 215 LAMHALRRDECAMALVGGATVMSTPQMFVEFSRQRGLAPDGRCKPFAAAADGTGWSEGVG 274 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DAVR+G + AV++GSA+NQDGAS GLT PNG +QQRVI AL AGL +D Sbjct: 275 LLLVERLSDAVRNGYPVLAVLKGSAVNQDGASNGLTAPNGPSQQRVIRQALTGAGLAASD 334 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 + +EAHGTGT+LGDP+EA A G RA + P +GS K+NIGH + Sbjct: 335 IDAVEAHGTGTTLGDPVEAHALLATYGQQRAADRPCGLGSMKSNIGHTQAAAGIAGVMKM 394 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP+ L+ + P+ H+ W ++ E PW G+PR A VSSFG +GTNAH Sbjct: 395 VLAMRHGHLPRTLHLDEPTGHVDWSEGNARLLAEPEPWPSAGRPRRAAVSSFGISGTNAH 454 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQARLAD 490 VILE+APA EP P LP LSART L A LR A Sbjct: 455 VILEQAPAHEAEPAPEPAARP---GALPWILSARTEAGLRAQADRLGRHLRDRADLEPAA 511 Query: 491 VSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQ 550 V+H R +E RA +V RE + L ALA R A GLV G + +A +A+LF GQ Sbjct: 512 VAHALADTRTLMEHRAVVVAGDREEFLRGLDALAAGRTANGLVSGVAVKA-ASAFLFAGQ 570 Query: 551 GSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESP-LRHTT 609 GSQ PGM REL PVFA + L++PL D++F A+E G E+ L T Sbjct: 571 GSQRPGMGRELHAAHPVFATAFDAVCAELDPHLDRPLRDIVF-AEE--GSAEAALLDQTA 627 Query: 610 YAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLF 669 Y Q ALFA+E L RL +SWG P V GHS+G+ +AA V+GV + D ARL+A RG L Sbjct: 628 YTQAALFALETALFRLVESWGVAPRFVAGHSIGELTAAHVSGVLTLHDAARLVAARGTLM 687 Query: 670 GSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGA-NTVLSGPAKDLESAVATLVAD 727 +LPAGG M AV T E ERL +++AA NG +TV+SG + + A A Sbjct: 688 QALPAGGAMVAVQATEDEIRERLAGHEDHVALAAANGPDSTVISGDEQAVTEIAAHWEAQ 747 Query: 728 GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAY 787 G R L SHAFHS +D +L+DF A+ L + P+ ++ TG+ Y Sbjct: 748 GRRTKRLRVSHAFHSPHMDDMLEDFRRVARGLTFHAPRIPVVSTVTGALATEDELRSPDY 807 Query: 788 WRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLT---ATALAAWPDPATTPQVLASLR 844 W R R+ V F +VRTL +EIG VLT L +P P +L + R Sbjct: 808 WVRQVRETVRFCAAVRTLEAEGVTTFVEIGTGGVLTPMVQDCLTTLEEPVLVP-LLRTGR 866 Query: 845 PTTADHRQITEAVAAAYAAGHLPDFRAF-RQPDARKLDLPTYPFEHRQFWFSDNRAIDRD 903 P T +TE VA A+ G D AF P + DLPTY F+ + +W D D Sbjct: 867 PETV---ALTEGVATAFVHGVPVDRSAFPGAPGTSRADLPTYAFQRQWYWLD---PADHD 920 Query: 904 TQTASAGSVTPHRTQAVRLLEDGQIEELAAL--IDGETVDEQTLRVLNKLAARHNQQRST 961 A+A A ED ++EL+A+ IDG D L L++ Q+R+ Sbjct: 921 EGEAAAAEAGEAGFWAAVERED--LQELSAVLAIDGSEADSLG-SFLPTLSSWRRQRRTQ 977 Query: 962 HVDPDARYEIRWDXXXXXXXXXXXXXDWILV----GDDTAAVLEFADALTAGGHRHQIVA 1017 Y W W++V G D DAL G + Sbjct: 978 AAADRFSYRTHW-APRTASGGPTATGHWLVVLPEGGTDDPWTARLLDALNDQGLHTDVRE 1036 Query: 1018 LPGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAAN 1077 LP +A R G L ++ + + P R L Sbjct: 1037 LPADHEPDA----WGRHPVDGVLCLLALDERPTRSCP------PYRRGLAATTNAAARPE 1086 Query: 1078 DAELRSPIWLVTRDGQRVTDTDTV-VPEQSCLWGFGRAAALELPHIWGGLADLSGADTEW 1136 A +++P+W VTR V + + P Q+ WG GR AALE P WGGL DL D Sbjct: 1087 GAGIQAPLWCVTRGAVAVDRHEALKSPLQAQTWGLGRVAALESPQSWGGLIDL--PDNLD 1144 Query: 1137 PRLIARITSPRDG-EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIG 1195 R ++ + S G EDQ+A+R V+A RL R T DT T LVTGG GA+G Sbjct: 1145 GRAVSALLSTLAGEEDQVAVRPAGVFARRLERIT-PGGDTGDRWSTHGTVLVTGGTGALG 1203 Query: 1196 LEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMT 1255 +A +LA GA H+VLT RR P V + D AD +A ++ Sbjct: 1204 AHLAHWLADAGAEHLVLTGRRGPQAPGAPELAAALTDRGVKVTLAACDAADRDALAAVLA 1263 Query: 1256 TVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFF 1315 + L PL G+VHAAG + L L + V K A +L E DL DLD F Sbjct: 1264 DIPPHL-PLTGVVHAAGVLDDGVLDALTPERFETVLRPKARAAQNLHELTQDL--DLDHF 1320 Query: 1316 VSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGP-WAAGMADAESRAR 1374 V SSI V G GQ Y AANA+LD LA +G+ A SV++GP AA D+++ R Sbjct: 1321 VLFSSIVGVLGNAGQANYAAANAYLDALAEHRLAQGLPATSVSWGPGQAAAWHDSDAADR 1380 Query: 1375 LEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXX 1434 + + G+ ++ A + G Q VA IDWS + P + +L Sbjct: 1381 MSRDGLLPMAAAPRRRPAPALAQGMTQVTVADIDWSAYAPALTAVRPSPLIGDLPEARRA 1440 Query: 1435 XXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFD 1494 + L P +Q K+ +T A + D + + F + Sbjct: 1441 LGPAEGPRRERSPLRDRIGAL--PPAEQEKAFLTMVREEAARVLGHPSPDTVDAQRAFRE 1498 Query: 1495 LGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTV 1554 G DSLMAV+LR R+ G +P TL+ DHP AA L EVLG V QAS Sbjct: 1499 QGFDSLMAVDLRNRLSAATGLRLPATLLFDHPTPLAAAACLRSEVLGAAGPATVVQAS-- 1556 Query: 1555 TARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTP 1612 TA D+P+A++ ++CRFP G PE+ W LLA G DAI +P DR WD+D Y PDPD Sbjct: 1557 TAALDEPVAIIGMACRFPGGVHSPEALWRLLAEGGDAITPMPADRGWDLDRLYHPDPDHQ 1616 Query: 1613 GKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGS 1672 G +Y R +FFGISPREA+ ++PQQRL+LET WE LE+AG P LRGS Sbjct: 1617 GTSYARGGGFLDGAADFDADFFGISPREALAMDPQQRLLLET-WEVLEQAGIDPESLRGS 1675 Query: 1673 RTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACS 1732 TGVF G +Y L A D+ H +TGNA++ +SGRV++ GFEGPA+ VDTACS Sbjct: 1676 STGVFAGTNTQDYGTALDAAQ-DEAGGHRLTGNAMSVVSGRVSYTFGFEGPALTVDTACS 1734 Query: 1733 SALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGY 1792 S+LVA+H A QAL+ G+C LA+AGGV V+ +P + V +R R L+P GRCK F A+ADG Sbjct: 1735 SSLVALHMAAQALRQGECSLAVAGGVTVMATPSSFVEFARQRGLAPDGRCKPFAAAADGT 1794 Query: 1793 VRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLAR 1852 SEG G+L+++RLSDA R+G +V AV+ S+VNQDGAS+GL+ P+G +QQR+I LA Sbjct: 1795 GWSEGVGLLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLSAPSGPSQQRVIRQALAN 1854 Query: 1853 AGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASG 1912 A ++ ++VD +EAHGTGT LGDPIE Q PLL+G+VK+N+GHT++A+G Sbjct: 1855 ARVAASEVDAVEAHGTGTTLGDPIEAQ----ALLATYGQERPLLLGAVKSNLGHTQAAAG 1910 Query: 1913 AAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFG 1972 AG++K+VL+++HG+LP++LH + P+ H+ W A V ++ E W G RRA VS+FG Sbjct: 1911 VAGVMKMVLAMRHGMLPRTLHVDEPTGHVDWTAGAVELLTEHTDWPETGHPRRAAVSAFG 1970 Query: 1973 FTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV------LALSARSPEALVE 2026 +GTNAHV++E + D +P L LSA+S AL Sbjct: 1971 ISGTNAHVVLELPAAEQPLVEQPSAAEPDAPATAPDRTPTASDGTAPLLLSAKSESALRA 2030 Query: 2027 LARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAAL-VVDSVXXXXXXXXXXXXXXTPA 2085 A R L P L + D +T R+ F +RAA+ D PA Sbjct: 2031 QAARLHSHLERDPALRLTDAAYTLMTHRTAFAHRAAVRAADHEAALRALTALAAGEADPA 2090 Query: 2086 GVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDV 2145 V H A LF+GQGSQ GM REL PVFA+ A+ + L RPL DV Sbjct: 2091 --VDTGTAHTGRDAVLFSGQGSQRIGMGRELSGRYPVFAEAFDTVCAALDEHLDRPLRDV 2148 Query: 2146 LFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVF 2205 + D E LL T +AQ LFA+E+ L RL +SW + P V GHSVG+ AAA VAGVF Sbjct: 2149 VRGEDEE---LLNRTVYAQAGLFAIEVALFRLVESWGVRPHYVAGHSVGEIAAAHVAGVF 2205 Query: 2206 SLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNT-VLSG 2264 SL D L+A RGR+ +LP GG M A+ A + V + VS+ A NGP++ V+SG Sbjct: 2206 SLADACALVAARGRLMQALPAGGAMAAIRATEDEVLPHLAD--SVSIAAVNGPSSVVVSG 2263 Query: 2265 PGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNR 2324 + I FE G + T L SHAFHS L+DP+L P L +V N Sbjct: 2264 AEHAVLSIAAHFEGAGRKTTRLRVSHAFHSPLMDPMLADFRAVAEGLTYGEPELAVVSNV 2323 Query: 2325 TGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPE 2384 TG + T +YW H R V+FA+ +R + A G + +E+GP VL+ A + P+ Sbjct: 2324 TGQLATPDQLRTPEYWVTHVRAAVRFADGIRALGAEGVTRFLELGPDGVLSALARESAPD 2383 Query: 2385 HMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAA-VHRQPRRPVELPTYPFQRRR 2443 LRK ++ + AL +V G D+ A + + V+LPTY FQ +R Sbjct: 2384 DAV---CTPVLRKDRSEAATLLAALTHLHVHGTEIDWTAFLAGRDAHAVDLPTYAFQHQR 2440 Query: 2444 FWPKASSIAVDGGTAASGILGSGKDLASG--------DTIYTSRLSVKSQPWLADHVIYG 2495 FWP G A G+ +G L S ++T+RLS+++ PWLA HV+ G Sbjct: 2441 FWPTPDHTRT-GDLGAVGLEATGHPLLSAAVELPDGEGLLFTTRLSLQTHPWLAGHVVMG 2499 Query: 2496 TVVVPGATYAAMALAAVGTPA--RLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQ 2553 +V++PG +A +AL A R+ ++ P++LPE ++QL + PAD + Sbjct: 2500 SVLLPGTAFAELALRAADEVGCDRVDELTLAAPLVLPEHGGVQLQLRVGPADASGRRTLT 2559 Query: 2554 IHSRPYGERGADWSLNAEGTVDTAGSDPDAAAD---EQSDPVDEVIERLERMRPQDLFET 2610 SR G+ W +A G + S P+ D E P D L + P Sbjct: 2560 ARSRAEGDGDRPWVQHATGVLAEGESTPEPGYDFHTESWPPADAAPVELSGLYPD----- 2614 Query: 2611 FADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXX 2670 FA +GP + G L++ W E ++ + AE + + +HP L+D V Sbjct: 2615 FAAHGFDYGPHFQG-LRTAWRRGDEVFAEVALPAEAEGEASAYGLHPALLDAALHVVAF- 2672 Query: 2671 XXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGG 2730 GV+ +P + V L R H ++ D G Sbjct: 2673 --------NGVDRGVVPFSWESVALHATGASAVRIRVVRHSG------DTVSVDVADTTG 2718 Query: 2731 RALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDEL 2790 + I ++ + L G L+ + W+ V PP A +A L Sbjct: 2719 EPVASIGTLVLRAVSADQLAGGADPAVRDALFRVQWNPVRLPP----AGAAVTVATLGSL 2774 Query: 2791 AAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXX 2850 A P D DL L AR +G V G Sbjct: 2775 AG-----APFDGYPDLASL--------ARSGRVAGAVLVPVEAG------------AGEV 2809 Query: 2851 XITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACE-------SGEPVDPVQAALWGFGRTT 2903 +++ A HA ++ L W+ + A + D AA+WG R+ Sbjct: 2810 VADDVVGATHATAARALDLARS-WLADDRFAASRLVFVTRGAVSGADLAGAAVWGLVRSA 2868 Query: 2904 INEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGH 2961 ++E P LVD D +E EP++ VR G++LA+RL A+S H Sbjct: 2869 LSEHPG-RFGLVDLDDDAELA----LVPRVLASDEPQLLVRGGEVLAARLAR-AQSSH 2920 Score = 907 bits (2343), Expect = 0.0 Identities = 628/1678 (37%), Positives = 858/1678 (51%), Gaps = 119/1678 (7%) Query: 1024 DEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRA--ANDAEL 1081 D A L + R A A +V + AG G D++ H T L R+ A+D Sbjct: 2784 DLASLARSGRVAGA---VLVPVEAGAGEVVA-DDVVGATHATAARALDLARSWLADDRFA 2839 Query: 1082 RSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIA 1141 S + VTR D + +WG R+A E P +G L DL D L+ Sbjct: 2840 ASRLVFVTRGAVSGADL-----AGAAVWGLVRSALSEHPGRFG-LVDLD--DDAELALVP 2891 Query: 1142 RITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGY 1201 R+ + E Q+ +RG V A RL R + T P T LVTGG G +G +A + Sbjct: 2892 RVLA--SDEPQLLVRGGEVLAARLARAQSSHAVTWDP---SGTVLVTGGTGGLGRVMARH 2946 Query: 1202 LA-SHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAE 1260 L HG +++L SRR P +V V DV DA VA L+ Sbjct: 2947 LVVEHGVRNLLLVSRRGPAAEGAEELVTELRHSGAEVAVEACDVTDAAAVADLVARHR-- 3004 Query: 1261 LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS 1320 ++ +VH AG + + L + V KV AW+L EA DL DLD FV SS Sbjct: 3005 ---ISAVVHTAGVLDDGVVESLTPERLSAVLRPKVDAAWNLHEATRDL--DLDAFVVFSS 3059 Query: 1321 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG------MADAES--- 1371 +A G GQ Y A NAFLD LA R G+ A S+ +GPW+ + D +S Sbjct: 3060 VAGTIGSPGQANYAAGNAFLDALAHHRRAAGLPAASLAWGPWSRDGGMTGTLTDVDSSAS 3119 Query: 1372 ---RARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSEL 1428 AR R R L A AG A ++ PV + DW+ + + L Sbjct: 3120 PGRHARTHPRTGRGLFDAALAAGDAHLL--PV-----RFDWASLRA-------QGEVPPL 3165 Query: 1429 ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIR 1487 L LV +L+ +R+ ++ + +R +A V + + I Sbjct: 3166 LRGLIRTRARRSAVGGSAAAAGLVGRLSGRGTVERREVLLDLVRAQIAVVLGHANPETIE 3225 Query: 1488 DEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTN 1547 F DLG DSL AVELR R+ G + T V D+P D+LL E+ G E+ Sbjct: 3226 STRVFQDLGFDSLTAVELRNRLNNATGLRLSATAVFDYPTADALVDFLLDELFGAQEEAE 3285 Query: 1548 V-RQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDR-WDIDEF 1604 + + DDP+ +V +SCR+PG PE W L++ GVDA+ + P DR WD++ Sbjct: 3286 LPAPVPSPAGAADDPVVIVGMSCRYPGGVGSPEDLWRLVSEGVDAVSDFPTDRGWDVESL 3345 Query: 1605 YDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGY 1664 Y PDP+ G +YTR P+FFG+SPREA+ + QQRL+LET WE +ER G Sbjct: 3346 YSPDPEALGTSYTRSGGFLHEAAEFDPDFFGMSPREALATDAQQRLLLETTWEAIERTGI 3405 Query: 1665 APSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPA 1724 P+ LRGSRTGVF GV +Y LL D+ E + G+A + SGRV++ GFEGPA Sbjct: 3406 DPASLRGSRTGVFAGVMYTDYGDLLVG---DQFEGYRSNGSAASIASGRVSYTFGFEGPA 3462 Query: 1725 VAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKT 1784 V VDTACSS+LVA+H A Q+L+SG+C LA+AGGV V+ +P T V SR R LS GRCK Sbjct: 3463 VTVDTACSSSLVALHWAAQSLRSGECSLAVAGGVTVMSTPTTFVEFSRQRGLSADGRCKA 3522 Query: 1785 FDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQR 1844 F +ADG EG G+LVL+RLSDA R+G RV AV+ S+VNQDGAS+GLT PNG AQQR Sbjct: 3523 FADAADGVGWGEGVGMLVLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQR 3582 Query: 1845 LIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNI 1904 +I LA AGLS ADVD +EAHGTGT LGDPIE Q PLL+GSVK+NI Sbjct: 3583 VIRQALASAGLSAADVDAVEAHGTGTTLGDPIEAQALLATYGQERPEDRPLLLGSVKSNI 3642 Query: 1905 GHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVR 1964 GH ++ASG AG+IK+VL+++HGVLP++LH + PS H+ W A V ++ W R Sbjct: 3643 GHAQAASGVAGVIKMVLAMRHGVLPRTLHVDEPSSHVDWSAGAVELLTSEAEWPQGEGPR 3702 Query: 1965 RAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEAL 2024 RAGVSSFG +GTNAHV++E+ P TD LSAR+ AL Sbjct: 3703 RAGVSSFGVSGTNAHVILEQPGPDAADAAPDATV--------TDPGALAWVLSARNEAAL 3754 Query: 2025 VELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTP 2084 A R ++ + L D+ H+ GRS F +RA + Sbjct: 3755 RCQAARLLSLVAGSDALCARDIGHSLVTGRSSFAHRAVVWGQDRDALVRALSALAVGEAD 3814 Query: 2085 AGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLD 2144 AG+ G TA+LF+GQGSQ GM EL+ PVFA A+ + L RPL D Sbjct: 3815 AGLAEGAS-GAGRTAFLFSGQGSQRLGMGWELYARYPVFADAFDAVCAALDEHLERPLRD 3873 Query: 2145 VLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGV 2204 V++ D A+LL T++AQ LFA+E+ L RL +SW + PD V GHS+G+ AAA V+GV Sbjct: 3874 VVWGED---AELLNQTAYAQAGLFAIEVALYRLAESWGMRPDFVAGHSIGEVAAAHVSGV 3930 Query: 2205 FSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNT-VLS 2263 FSL D L+A RGR+ LP GG M+A+ A + V E VS+ A NGP++ V+S Sbjct: 3931 FSLPDACALVAARGRLMQQLPSGGAMMAIRATEDEVLPHLAE--GVSLAAVNGPSSVVIS 3988 Query: 2264 GPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCN 2323 G + + I F EG + T L SHAFHS L++P+L+ PT+P+V N Sbjct: 3989 GAEDAVLAIAAHFAGEGRKTTRLRVSHAFHSPLMEPMLEEFRAVVTRLSFGTPTIPVVSN 4048 Query: 2324 RTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWP 2383 TG + + A YW RH R+ V+FA+ ++ + A G + +E+GP VL+ A Sbjct: 4049 LTGRLAEPEQLAHADYWVRHVREAVRFADGIQALRAEGVTRFLELGPDGVLSAMA----- 4103 Query: 2384 EHMAAPRAVAS--LRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQ 2440 A+ AV + LR+ + + ALA YV G D+ R +LPTY FQ Sbjct: 4104 RESASDDAVLAPVLRRDRPEETALLGALAQLYVRGAHVDWTVPFAGSGARWADLPTYAFQ 4163 Query: 2441 RRRFWPKASSIAVDG-------GTAASGILGSGKDLA-SGDTIYTSRLSVKSQPWLADHV 2492 RFWP + +A G G+A +LG+ +LA SG ++T RLSV S PWLADHV Sbjct: 4164 HERFWP-SGGVARPGDVRSAGLGSAGHPLLGAAVELAGSGGLLFTGRLSVSSHPWLADHV 4222 Query: 2493 IYGTVVVPGATYAAMALAAVGTPA--RLKDVFFYEPIILPEK-ASREVQLTLHPADGGSV 2549 + G+V+VPG + L A L+++ P++LP A+ +VQ+ + D Sbjct: 4223 VLGSVLVPGTALVELVLRAADEAGCDLLEELTLAAPLVLPASGAAVQVQVAVGEPDEAGR 4282 Query: 2550 LSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAA----DEQSDPVDEVIERLERMRPQ 2605 +H+R E W+L+A G V + P A + ++PVD Sbjct: 4283 RPVSVHAR---EGEGPWTLHASGAVTSGAEVPPFDATVWPPKGAEPVDVA---------- 4329 Query: 2606 DLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEP--MHPVLMD 2661 D ++ AD L +GP + G L++ W + GD+ A+L E + +HP L D Sbjct: 4330 DCYDVLADAGLTYGPAFHG-LQAAW----KLGGDVYAEAKLPESTDGDAYGLHPALFD 4382 Score = 898 bits (2321), Expect = 0.0 Identities = 665/1914 (34%), Positives = 933/1914 (48%), Gaps = 169/1914 (8%) Query: 1110 GFGRAAALELPHIWGGLADLSG-ADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRR 1168 G R+A E P +G L D+ G ADT P P ++ +RG V A RLVR Sbjct: 4566 GLVRSAQSENPGRFG-LVDMDGDADTTVPAQALATDEP-----ELLVRGGEVLAARLVRA 4619 Query: 1169 TGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXX 1227 + T P T L+TGG G +G VA +L S HG ++L SRR P Sbjct: 4620 QSSHTVTWDP---SGTVLITGGTGGLGRSVARHLVSEHGVRSLLLVSRRGPAAEGAGELV 4676 Query: 1228 XXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEV 1287 +V + DV DA VA L+ ++ +VH AG + + L + Sbjct: 4677 AELRGSGAEVVIEACDVTDAVAVADLVARHR-----ISAVVHTAGVLDDGVVESLTPERL 4731 Query: 1288 DRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRL 1347 V KV AW+L EA L DLD FV SS+A +G GQ Y A NAFLD LA+ Sbjct: 4732 AVVLRPKVDAAWNLHEATRGL--DLDAFVVFSSVAGTFGSAGQANYAAGNAFLDALAYHR 4789 Query: 1348 RERGVTAVSVNFGPWA--AGMADAESRA---RLEQRGVRTLSPAEALAGMADVVAGPVQG 1402 R G+ AVS+ +GPW+ GM S A R+ ++G+ L+ E LA + D G + Sbjct: 4790 RAVGLPAVSLAWGPWSQDGGMTGTLSDADVQRIARQGMPPLTVEEGLA-LFDAALGSAEP 4848 Query: 1403 VVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQ 1462 + LP+ E + L + ++L + Sbjct: 4849 MA--------LPVRLDLAALRAQGEPQPLLRGLIRTRTRRSGAAAASGIAQRLAGLSTAE 4900 Query: 1463 RKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTL 1521 R+ + + +R +A V + I + F DLG+DSL A+ELR + + G +P T Sbjct: 4901 RREALLDVVRAQIATVLGHAGPETIAPDRAFQDLGLDSLTAIELRNLLGKATGLRLPATT 4960 Query: 1522 VMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVT---ARTDDPIAVVAVSCRFPGA-PDP 1577 V D+P + A +LL E+ G T V + DDP+ +V +SCRFPG P Sbjct: 4961 VFDYPTVDALAAHLLDELFGAETGTATETPLPVPGLPSLADDPVVIVGMSCRFPGGVASP 5020 Query: 1578 ESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGI 1636 E W L+A GVDA+ P DR W+ID+ YDP+ + G TR PEFFG+ Sbjct: 5021 EDLWRLVADGVDAVSAFPTDRGWEIDDTYDPERE--GAIATRSGGFLHDAAEFDPEFFGM 5078 Query: 1637 SPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDK 1696 SPREA+ + QQRL+LET WE LERAG P+ LRGSRTGVF GV ++Y+ LLS + Sbjct: 5079 SPREALTTDAQQRLLLETTWEALERAGMDPATLRGSRTGVFAGVMYHDYSTLLSGREFEG 5138 Query: 1697 IEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAG 1756 + +G+A + SGRV++ GFEGPAV VDTACSS+LVA+H A Q+L+SG+C LALAG Sbjct: 5139 YQG---SGSAGSVASGRVSYTFGFEGPAVTVDTACSSSLVALHLAAQSLRSGECSLALAG 5195 Query: 1757 GVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRV 1816 GV V+ +P+T V SR LS GRCK F +ADG +EG G+LVL+RLSDA R+G R+ Sbjct: 5196 GVTVMSTPLTFVEFSRQGGLSADGRCKAFADAADGVGWAEGAGILVLERLSDARRNGHRI 5255 Query: 1817 CAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPI 1876 A + S+VNQDGAS+GLT PNG AQQR+I LA AGLS ADVD +EAHGTGT LGDPI Sbjct: 5256 LATVRGSAVNQDGASNGLTAPNGPAQQRVIRQALASAGLSAADVDAVEAHGTGTTLGDPI 5315 Query: 1877 EVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFEN 1936 E Q PLL+GSVK+NIGH ++ASG AG+IK+VL+++HGVLP++LH + Sbjct: 5316 EAQALLATYGQERPEDRPLLLGSVKSNIGHAQAASGVAGVIKMVLAMRHGVLPRTLHVDE 5375 Query: 1937 PSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPP---QLHXXX 1993 PS H+ W A V ++ W RRAGVSSFG +GTNAHV++E+ P + Sbjct: 5376 PSSHVDWSAGAVELLTSEAEWPQGEGPRRAGVSSFGISGTNAHVILEQPEPVAAETESIT 5435 Query: 1994 XXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVG 2053 +P LS RS AL A R L PG I DV ++ G Sbjct: 5436 PDTAPDAAEDEAADSGTPVPALLSGRSASALRAQAARLLSRLDGDPGPRITDVAYSLATG 5495 Query: 2054 RSHFEYRAALVVDSVXXXXXXXXXXXXXXTPA-GVVRGEHVHRPTTAWLFTGQGSQYPGM 2112 RS F +RA ++ + T A VV + A+LF+GQGSQ GM Sbjct: 5496 RSAFPHRAVILAANRADLLHSLSALAEGHTEAPAVVAQDRARSGKLAFLFSGQGSQRLGM 5555 Query: 2113 ARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEM 2172 REL+ P FA+ + A+ L RPL DV++ D A+LL T +AQ LFA+E+ Sbjct: 5556 GRELYGRYPAFAEALDAVCAALDAHLDRPLRDVIWGED---AELLNRTGYAQTGLFAIEV 5612 Query: 2173 GLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVA 2232 L RL +SW + PD +LGHS+G+ AAA VAGV SL D L+A RGR+ LP GG M+A Sbjct: 5613 ALFRLLESWGVRPDHLLGHSIGEIAAAHVAGVLSLPDACALVAARGRLMQQLPSGGAMMA 5672 Query: 2233 VFADAEHVEQVAGEFPRVSVGAYNGPNT-VLSGPGEDLEEIVERFEDEGIRCTWLATSHA 2291 + A + V E VS+ A NGP++ V+SG +++ + FE+EG + T L SHA Sbjct: 5673 IRATEDEVLPHLAE--GVSLAAVNGPSSVVVSGAEDEVLALAAHFEEEGRKTTRLRVSHA 5730 Query: 2292 FHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFA 2351 FHS L++P+L P +P+V N TG T + A+YW H R+ V+FA Sbjct: 5731 FHSPLMEPMLADFRAVADGMTYAAPRIPVVSNVTGRPATAEELCCAEYWVGHVREAVRFA 5790 Query: 2352 ESVRTVAALGCSVLMEIGPQPVLTG-AAVQVWPEHMAAPRAVASLRKGVADRRQIADALA 2410 + V + G + +E+GP L+ AA + + AP LRK + + ALA Sbjct: 5791 DGVGALREQGVTTFLELGPDGSLSALAAESAADDSVLAP----VLRKNRPEAPALLTALA 5846 Query: 2411 SAYVGGHRPDF-AAVHRQPRRPVELPTYPFQRRRFWP-----KASSIAVDG-GTAASGIL 2463 + G D+ AA R V+LPTY FQ RFWP +A + G G+A +L Sbjct: 5847 RLHAQGTPVDWSAAFAGTGARWVDLPTYAFQHERFWPSGGAARAGDVRSAGLGSAGHPLL 5906 Query: 2464 GSGKDLA-SGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTP--ARLKD 2520 G+ +LA SG + T RLS+ S PWLADHV+ G+V+VPG + L A A + + Sbjct: 5907 GAAVELAGSGGRLLTGRLSLSSHPWLADHVVLGSVLVPGTALMELVLRAADEVDCAAVDE 5966 Query: 2521 VFFYEPIILPEK-ASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGS 2579 + P++LP A+ +VQ+ + D +H+R E W+L+A+G + A Sbjct: 5967 LTLAAPLVLPASGAAIQVQVWVGEPDEAGRRPVSVHAR---EGEGPWTLHADGALAPAA- 6022 Query: 2580 DPDAAADEQSDPVDEVI---ERLERMRPQDLFETFADLELAWGPTWSGSLKSLW-LGDGE 2635 ++ P D I + E + +E FAD A+GP + G L++ W LG+ Sbjct: 6023 --------ETVPFDTAIWPPQGAEHLDAAGCYERFADAGFAYGPVFQG-LRAAWKLGED- 6072 Query: 2636 AVGDILVGAELAEQLGSE----PMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYG 2691 + AE+A G++ +HP L D +G ++ +P + Sbjct: 6073 ------IYAEVALPEGTDGNAYGLHPALFDAALHAALLGG-------EGTDEAAVPFSWN 6119 Query: 2692 QVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLR 2751 VTL R R R + VD G + +R T + L Sbjct: 6120 GVTLHATGASRVRVRIRPTEGGT-------SIALVDTAGAPVASVRSLTARPITAGQLQT 6172 Query: 2752 GLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLG- 2810 G L+ + W + D+ + + G D + + + + DL L Sbjct: 6173 G----DRDSLFQVDWTTL---HLTDERANSLALLGKD--TEGILDTLSLQPHADLDDLAA 6223 Query: 2811 -----EVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGP 2865 VL+ R AG + +VHAA Sbjct: 6224 TGVHDTVLAPLPTRTAG--------------------------------TVESVHAATTG 6251 Query: 2866 SVKLPGGLWIVTEHGVACE-------SGEPVDPVQAALWGFGRTTINEEPALHCRLVDCD 2918 ++ L W+ + A + D A++WG R+ + E P LVD D Sbjct: 6252 ALALIRS-WLADDRFAASRLVFVTRGAVSGTDLAGASVWGLVRSALLEHPG-RFGLVDVD 6309 Query: 2919 GSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGGDFVL 2972 +A EP++ VR G++LA+RL+ S +T G ++ Sbjct: 6310 VDQDA--EVPLVPRALASDEPQVLVRGGEVLAARLVRAQSSDTVTWDPSGTVLI 6361 Score = 649 bits (1673), Expect = 0.0 Identities = 381/901 (42%), Positives = 504/901 (55%), Gaps = 22/901 (2%) Query: 16 IIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAG 73 I+G + R+PG S E+ W L+ +G +A+SD P DR WD+E + PDP G TR G Sbjct: 3303 IVGMSCRYPGGVGSPEDLWRLVSEGVDAVSDFPTDRGWDVESLYSPDPEALGTSYTRSGG 3362 Query: 74 FVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLA 133 F+ + FD FFGMS RE D Q R+L+ET W A+E +GI P SL S TGVF G+ Sbjct: 3363 FLHEAAEFDPDFFGMSPREALATDAQQRLLLETTWEAIERTGIDPASLRGSRTGVFAGVM 3422 Query: 134 THDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQ 193 DY D L + E Y + G++ + A+GR+SY G +GPAV VDTACSSSLVA+H Sbjct: 3423 YTDY----GDLLVGDQFEGYRSNGSAASIASGRVSYTFGFEGPAVTVDTACSSSLVALHW 3478 Query: 194 ACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGV 253 A Q+LR EC LA+AGG V+ TP T + FS L+ DGRCK F AADG GEG G+ Sbjct: 3479 AAQSLRSGECSLAVAGGVTVMSTPTTFVEFSRQRGLSADGRCKAFADAADGVGWGEGVGM 3538 Query: 254 VVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADV 313 +V++RL DA R+G R+ AV+RGSA+NQDGAS GLT PNG AQQRVI AL AGL ADV Sbjct: 3539 LVLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALASAGLSAADV 3598 Query: 314 GYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXXX 373 +EAHGTGT+LGDPIEAQA G R + PLL+GS K+NIGH + Sbjct: 3599 DAVEAHGTGTTLGDPIEAQALLATYGQERPEDRPLLLGSVKSNIGHAQAASGVAGVIKMV 3658 Query: 374 XXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAHV 433 + + LP+ L+ + PS H+ W +E++ W + PR AGVSSFG +GTNAHV Sbjct: 3659 LAMRHGVLPRTLHVDEPSSHVDWSAGAVELLTSEAEWPQGEGPRRAGVSSFGVSGTNAHV 3718 Query: 434 ILEE-APAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVS 492 ILE+ P A V DP + + LSAR AL A + D+ Sbjct: 3719 ILEQPGPDAADAAPDATVTDPGALAWV-LSARNEAALRCQAARLLSLVAGSDALCARDIG 3777 Query: 493 HTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQGS 552 H+ T R+ RA + R++ + L ALA GL G S A +TA+LF+GQGS Sbjct: 3778 HSLVTGRSSFAHRAVVWGQDRDALVRALSALAVGEADAGLAEGAS-GAGRTAFLFSGQGS 3836 Query: 553 QYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYAQ 612 Q GM EL+ PVFA+ A+ + LE+PL DV++ G+ L T YAQ Sbjct: 3837 QRLGMGWELYARYPVFADAFDAVCAALDEHLERPLRDVVW------GEDAELLNQTAYAQ 3890 Query: 613 PALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGSL 672 LFA+E+ L RL +SWG PD V GHS+G+ +AA V+GVF + D L+A RGRL L Sbjct: 3891 AGLFAIEVALYRLAESWGMRPDFVAGHSIGEVAAAHVSGVFSLPDACALVAARGRLMQQL 3950 Query: 673 PAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVAT-LVADGVRC 731 P+GG M A+ + E L +S+AA NG ++V+ A+D A+A +G + Sbjct: 3951 PSGGAMMAIRATED--EVLPHLAEGVSLAAVNGPSSVVISGAEDAVLAIAAHFAGEGRKT 4008 Query: 732 DWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRH 791 L SHAFHS L++P+L++F + +L + P ++ N TG YW RH Sbjct: 4009 TRLRVSHAFHSPLMEPMLEEFRAVVTRLSFGTPTIPVVSNLTGRLAEPEQLAHADYWVRH 4068 Query: 792 ARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTADHR 851 R+ V FA ++ L LE+GP VL+A A + D A VL RP + Sbjct: 4069 VREAVRFADGIQALRAEGVTRFLELGPDGVLSAMARESASDDAVLAPVLRRDRP---EET 4125 Query: 852 QITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASAG 910 + A+A Y G D+ F AR DLPTY F+H +FW S A D ++A G Sbjct: 4126 ALLGALAQLYVRGAHVDWTVPFAGSGARWADLPTYAFQHERFWPSGGVARPGDVRSAGLG 4185 Query: 911 S 911 S Sbjct: 4186 S 4186 Score = 648 bits (1671), Expect = 0.0 Identities = 388/926 (41%), Positives = 517/926 (55%), Gaps = 38/926 (4%) Query: 7 PIEPTPSFA-----IIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDP 59 P+ PS A I+G + RFPG AS E+ W L+ DG +A+S P DR W+I++ +DP Sbjct: 4992 PVPGLPSLADDPVVIVGMSCRFPGGVASPEDLWRLVADGVDAVSAFPTDRGWEIDDTYDP 5051 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 + G + TR GF+ D FD FFGMS RE D Q R+L+ET W A+E +G+ P Sbjct: 5052 ERE--GAIATRSGGFLHDAAEFDPEFFGMSPREALTTDAQQRLLLETTWEALERAGMDPA 5109 Query: 120 SLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVA 179 +L S TGVF G+ HDY + S E E Y G++ + A+GR+SY G +GPAV Sbjct: 5110 TLRGSRTGVFAGVMYHDYSTLLSGR----EFEGYQGSGSAGSVASGRVSYTFGFEGPAVT 5165 Query: 180 VDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFD 239 VDTACSSSLVA+H A Q+LR EC LALAGG V+ TP T + FS L+ DGRCK F Sbjct: 5166 VDTACSSSLVALHLAAQSLRSGECSLALAGGVTVMSTPLTFVEFSRQGGLSADGRCKAFA 5225 Query: 240 AAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI 299 AADG EG G++V++RL DA R+G RI A +RGSA+NQDGAS GLT PNG AQQRVI Sbjct: 5226 DAADGVGWAEGAGILVLERLSDARRNGHRILATVRGSAVNQDGASNGLTAPNGPAQQRVI 5285 Query: 300 ADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGH 359 AL AGL ADV +EAHGTGT+LGDPIEAQA G R + PLL+GS K+NIGH Sbjct: 5286 RQALASAGLSAADVDAVEAHGTGTTLGDPIEAQALLATYGQERPEDRPLLLGSVKSNIGH 5345 Query: 360 LEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIA 419 + + + LP+ L+ + PS H+ W +E++ W + PR A Sbjct: 5346 AQAASGVAGVIKMVLAMRHGVLPRTLHVDEPSSHVDWSAGAVELLTSEAEWPQGEGPRRA 5405 Query: 420 GVSSFGFAGTNAHVILEEAPAVG------TPATT-EPVEDPRRYSVLP----LSARTPEA 468 GVSSFG +GTNAHVILE+ V TP T + ED S P LS R+ A Sbjct: 5406 GVSSFGISGTNAHVILEQPEPVAAETESITPDTAPDAAEDEAADSGTPVPALLSGRSASA 5465 Query: 469 LVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDR- 527 L A L P R+ DV+++ T R+ RA ++ +R + L ALA+ Sbjct: 5466 LRAQAARLLSRLDGDPGPRITDVAYSLATGRSAFPHRAVILAANRADLLHSLSALAEGHT 5525 Query: 528 PAPGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPL 587 AP +V + + K A+LF+GQGSQ GM REL+ P FAE + A+ L++PL Sbjct: 5526 EAPAVVAQDRARSGKLAFLFSGQGSQRLGMGRELYGRYPAFAEALDAVCAALDAHLDRPL 5585 Query: 588 LDVIFDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAA 647 DVI+ G+ L T YAQ LFA+E+ L RL +SWG PD ++GHS+G+ +AA Sbjct: 5586 RDVIW------GEDAELLNRTGYAQTGLFAIEVALFRLLESWGVRPDHLLGHSIGEIAAA 5639 Query: 648 CVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-A 706 VAGV + D L+A RGRL LP+GG M A+ + E L +S+AA NG + Sbjct: 5640 HVAGVLSLPDACALVAARGRLMQQLPSGGAMMAIRATED--EVLPHLAEGVSLAAVNGPS 5697 Query: 707 NTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQR 766 + V+SG ++ + A +G + L SHAFHS L++P+L DF + A + Y P+ Sbjct: 5698 SVVVSGAEDEVLALAAHFEEEGRKTTRLRVSHAFHSPLMEPMLADFRAVADGMTYAAPRI 5757 Query: 767 ILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATA 826 ++ N TG YW H R+ V FA V L + LE+GP L+A A Sbjct: 5758 PVVSNVTGRPATAEELCCAEYWVGHVREAVRFADGVGALREQGVTTFLELGPDGSLSALA 5817 Query: 827 LAAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDF-RAFRQPDARKLDLPTY 885 + D + VL RP + + A+A +A G D+ AF AR +DLPTY Sbjct: 5818 AESAADDSVLAPVLRKNRP---EAPALLTALARLHAQGTPVDWSAAFAGTGARWVDLPTY 5874 Query: 886 PFEHRQFWFSDNRAIDRDTQTASAGS 911 F+H +FW S A D ++A GS Sbjct: 5875 AFQHERFWPSGGAARAGDVRSAGLGS 5900 Score = 645 bits (1665), Expect = 0.0 Identities = 381/911 (41%), Positives = 518/911 (56%), Gaps = 34/911 (3%) Query: 1549 RQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDR-WDIDEFYD 1606 +Q A+ +P+A+V+++CRFPG PE WELL GVDA+ P +R WD+D Y Sbjct: 23 QQLDETEAKQREPLAIVSMACRFPGGVRSPEELWELLRDGVDAVSSFPRNRGWDLDALYH 82 Query: 1607 PDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP 1666 DP G +Y R P FFGISPREA+ ++PQQRL+LET WE +ERAG P Sbjct: 83 SDPAHQGTSYAREGGFLHDAGEFDPGFFGISPREALAMDPQQRLLLETAWEAVERAGIDP 142 Query: 1667 SDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVA 1726 L GSRTGVF G Y D++ H +TGN ++ SGR+++ LG EGPA+ Sbjct: 143 ESLAGSRTGVFVGTGHGGY-DAEGRRRADEVGGHLLTGNHISIASGRISYVLGLEGPALT 201 Query: 1727 VDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFD 1786 VDTACSS+LVA+H A AL+ +C +AL GG V+ +P V SR R L+P GRCK F Sbjct: 202 VDTACSSSLVALHLAMHALRRDECAMALVGGATVMSTPQMFVEFSRQRGLAPDGRCKPFA 261 Query: 1787 ASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLI 1846 A+ADG SEG G+L+++RLSDAVR+G V AV+ S+VNQDGAS+GLT PNG +QQR+I Sbjct: 262 AAADGTGWSEGVGLLLVERLSDAVRNGYPVLAVLKGSAVNQDGASNGLTAPNGPSQQRVI 321 Query: 1847 EATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGH 1906 L AGL+ +D+D +EAHGTGT LGDP+E P +GS+K+NIGH Sbjct: 322 RQALTGAGLAASDIDAVEAHGTGTTLGDPVEAHALLATYGQQRAADRPCGLGSMKSNIGH 381 Query: 1907 TESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRA 1966 T++A+G AG++K+VL+++HG LP++LH + P+ H+ W R++ EP PW + GR RRA Sbjct: 382 TQAAAGIAGVMKMVLAMRHGHLPRTLHLDEPTGHVDWSEGNARLLAEPEPWPSAGRPRRA 441 Query: 1967 GVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLA--------LSA 2018 VSSFG +GTNAHV++E+AP + +P+ A LSA Sbjct: 442 AVSSFGISGTNAHVILEQAPAH-----------------EAEPAPEPAARPGALPWILSA 484 Query: 2019 RSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXX 2078 R+ L A R L L+ A V H R+ E+RA +V Sbjct: 485 RTEAGLRAQADRLGRHLRDRADLEPAAVAHALADTRTLMEHRAVVVAGDREEFLRGLDAL 544 Query: 2079 XXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADML 2138 T G+V G V + +A+LF GQGSQ PGM REL PVFA + L Sbjct: 545 AAGRTANGLVSGVAV-KAASAFLFAGQGSQRPGMGRELHAAHPVFATAFDAVCAELDPHL 603 Query: 2139 PRPLLDVLFATDRET-ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYA 2197 RPL D++FA + A LL T++ Q ALFA+E L RL +SW + P V GHS+G+ Sbjct: 604 DRPLRDIVFAEEGSAEAALLDQTAYTQAALFALETALFRLVESWGVAPRFVAGHSIGELT 663 Query: 2198 AACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHV-EQVAGEFPRVSVGAYN 2256 AA V+GV +L D ARL+A RG + +LP GG MVAV A + + E++AG V++ A N Sbjct: 664 AAHVSGVLTLHDAARLVAARGTLMQALPAGGAMVAVQATEDEIRERLAGHEDHVALAAAN 723 Query: 2257 GP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXX 2315 GP +TV+SG + + EI +E +G R L SHAFHS +D +L+ Sbjct: 724 GPDSTVISGDEQAVTEIAAHWEAQGRRTKRLRVSHAFHSPHMDDMLEDFRRVARGLTFHA 783 Query: 2316 PTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLT 2375 P +P+V TGA+ T YW R R+ V+F +VRT+ A G + +EIG VLT Sbjct: 784 PRIPVVSTVTGALATEDELRSPDYWVRQVRETVRFCAAVRTLEAEGVTTFVEIGTGGVLT 843 Query: 2376 GAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQP-RRPVEL 2434 VQ + P V LR G + + + +A+A+V G D +A P +L Sbjct: 844 -PMVQDCLTTLEEPVLVPLLRTGRPETVALTEGVATAFVHGVPVDRSAFPGAPGTSRADL 902 Query: 2435 PTYPFQRRRFW 2445 PTY FQR+ +W Sbjct: 903 PTYAFQRQWYW 913 Score = 167 bits (424), Expect = 2e-38 Identities = 127/363 (34%), Positives = 166/363 (45%), Gaps = 14/363 (3%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA GA +VLT RR P + ++ A D Sbjct: 1194 LVTGGTGALGAHLAHWLADAGAEHLVLTGRRGPQAPGAPELAAALTDRGVKVTLAACDAA 1253 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A +LA I L PL G+ H AGVLDD +L A PERF T L PKA A + Sbjct: 1254 DRDALAAVLADIPPHL-PLTGVVHAAGVLDDGVLDALTPERFETVLRPKARAAQNLHELT 1312 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQANYA ANA LD L R AQGL AT +++GP GQ Sbjct: 1313 QDLDLDHFVLFSSIVGVLGNAGQANYAAANAYLDALAEHRLAQGLPATSVSWGP-GQAAA 1371 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 A ++ GL+P+ +A A +A G Q TV +W A L + RP L Sbjct: 1372 WHDSDAADRMSRDGLLPM-AAAPRRRPAPALAQGMTQVTVADIDWSAYAPALTAVRPSPL 1430 Query: 3538 DLVLPS---AAGEATGD----SELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA- 3589 LP A G A G S L ++ +P ++ ++ E L SP Sbjct: 1431 IGDLPEARRALGPAEGPRRERSPLRDRIGALPPAEQEKAFLTMVREEAARVLGHPSPDTV 1490 Query: 3590 -ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEA 3648 A F + G DSLMA++LRNRL + G + AT +FD+PT A L ++ A Sbjct: 1491 DAQRAFREQGFDSLMAVDLRNRLSAATG--LRLPATLLFDHPTPLAAAACLRSEVLGAAG 1548 Query: 3649 PET 3651 P T Sbjct: 1549 PAT 1551 Score = 166 bits (421), Expect = 5e-38 Identities = 174/564 (30%), Positives = 246/564 (43%), Gaps = 75/564 (13%) Query: 991 LVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGDG 1050 L+G DT +L D L+ H + L + + L L +AG + VH AA G Sbjct: 6198 LLGKDTEGIL---DTLSLQPHA-DLDDLAATGVHDTVLAP-LPTRTAGTVESVH-AATTG 6251 Query: 1051 AAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWG 1110 A A +R L A+D S + VTR TD + +WG Sbjct: 6252 ALALIRSWL----------------ADDRFAASRLVFVTRGAVSGTDL-----AGASVWG 6290 Query: 1111 FGRAAALELPHIWGGLADLS-GADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRT 1169 R+A LE P +G L D+ D E P + + S E Q+ +RG V A RLVR Sbjct: 6291 LVRSALLEHPGRFG-LVDVDVDQDAEVPLVPRALASD---EPQVLVRGGEVLAARLVRAQ 6346 Query: 1170 GEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXX 1228 + T P T L+TGG G +G VA +L S HG ++L SRR P Sbjct: 6347 SSDTVTWDP---SGTVLITGGTGGLGRSVARHLVSEHGVRSLLLVSRRGPAAEGVDALVA 6403 Query: 1229 XXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVD 1288 + V V DV DA VA L+ ++ +VH AG + + L + Sbjct: 6404 ELAECGAQVTVEACDVTDAVAVADLVARHR-----ISAVVHTAGVLDDGVVESLTPERLS 6458 Query: 1289 RVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLR 1348 V KV AW+L EA L DLD FV SS+A +G GQ Y A NAFLD LA+ R Sbjct: 6459 AVLRPKVDAAWNLHEATRGL--DLDAFVVFSSVAGTFGSAGQANYAAGNAFLDALAYHRR 6516 Query: 1349 ERGVTAVSVNFGPWA--AGMADAESRA---RLEQRGVRTLSPAEALA------GMADVVA 1397 G+ AVS+ +GPW+ GM S A R+ ++G+ L+ E LA G A+ +A Sbjct: 6517 AVGLPAVSLAWGPWSQDGGMTGTLSDADVQRIARQGMPPLTVEEGLALFDAALGSAEPMA 6576 Query: 1398 GPVQGVVAKI-----DWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLV 1452 PV+ +A + L + GRR + E + Sbjct: 6577 LPVRLDLAALRAQGEPQPLLRGLIRTPGRRTAAAATEGD---------------TAAAFA 6621 Query: 1453 EQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQ 1511 +LT + + ++ +R+ +A V +A EI + F DLG DSL AVELR R+ Sbjct: 6622 GRLTGLSAAEGREVVLGAVRSQIAGVLGHAEATEIDQDRAFLDLGFDSLTAVELRNRLGA 6681 Query: 1512 GVGKDIPVTLVMDHPRLSDAADYL 1535 G +P TL+ D+P ++ +L Sbjct: 6682 VTGIRLPATLLFDYPTPAELVAHL 6705 Score = 147 bits (372), Expect = 2e-32 Identities = 117/361 (32%), Positives = 171/361 (47%), Gaps = 21/361 (5%) Query: 3298 LITGGLGAIGLHTAAYLA-QLGAGDIVLTSRRDPDESAQRAIDEITE-RHK-CRIHTYAA 3354 L+TGG G +G A +L + G +++L SRR P +A+ A + +TE RH + A Sbjct: 2931 LVTGGTGGLGRVMARHLVVEHGVRNLLLVSRRGP--AAEGAEELVTELRHSGAEVAVEAC 2988 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXX 3414 DV D A VADL+AR R ++ + H AGVLDD ++ + PER L PK A + Sbjct: 2989 DVTDAAAVADLVARHR-----ISAVVHTAGVLDDGVVESLTPERLSAVLRPKVDAAWNLH 3043 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 PGQANYA NA LD L RRA GL A + +GPW + Sbjct: 3044 EATRDLDLDAFVVFSSVAGTIGSPGQANYAAGNAFLDALAHHRRAAGLPAASLAWGPWSR 3103 Query: 3475 -GGMASSEAATANITAQGL-IPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA 3532 GGM + + + G P +A G ++ +W + + G Sbjct: 3104 DGGMTGTLTDVDSSASPGRHARTHPRTGRGLFDAALAAGDAHLLPVRFDW-ASLRAQGEV 3162 Query: 3533 RPPILDLVLPSAAGEATGDSE----LLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPP 3588 P + L+ A A G S L+ +L +R + + ++ ++ L A+P Sbjct: 3163 PPLLRGLIRTRARRSAVGGSAAAAGLVGRLSGRGTVERREVLLDLVRAQIAVVLGHANPE 3222 Query: 3589 AASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDA 3646 S F DLG DSL A+ELRNRL++ G ++ATAVFDYPT L ++L+ +L A Sbjct: 3223 TIESTRVFQDLGFDSLTAVELRNRLNNATG--LRLSATAVFDYPTADALVDFLLDELFGA 3280 Query: 3647 E 3647 + Sbjct: 3281 Q 3281 Score = 146 bits (368), Expect = 7e-32 Identities = 123/359 (34%), Positives = 167/359 (46%), Gaps = 19/359 (5%) Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPD-ESAQRAIDEITERHKCRIHTYAAD 3355 LITGG G +G A +L ++ G ++L SRR P E A + E+ + A D Sbjct: 4634 LITGGTGGLGRSVARHLVSEHGVRSLLLVSRRGPAAEGAGELVAEL-RGSGAEVVIEACD 4692 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 V D VADL+AR R ++ + H AGVLDD ++ + PER L PK A + Sbjct: 4693 VTDAVAVADLVARHR-----ISAVVHTAGVLDDGVVESLTPERLAVVLRPKVDAAWNLHE 4747 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ- 3474 GQANYA NA LD L RRA GL A + +GPW Q Sbjct: 4748 ATRGLDLDAFVVFSSVAGTFGSAGQANYAAGNAFLDALAYHRRAVGLPAVSLAWGPWSQD 4807 Query: 3475 GGMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAA-KVLGS 3531 GGM S+A I QG+ PL L AL + A GS + L AA + G Sbjct: 4808 GGMTGTLSDADVQRIARQGMPPLTVEEGL-ALFDA-ALGSAEPMALPVRLDLAALRAQGE 4865 Query: 3532 ARPPILDLV-LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPP-- 3588 +P + L+ + A S + ++L + +R + + ++ ++ L A P Sbjct: 4866 PQPLLRGLIRTRTRRSGAAAASGIAQRLAGLSTAERREALLDVVRAQIATVLGHAGPETI 4925 Query: 3589 AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAE 3647 A F DLG DSL AIELRN L G + AT VFDYPT+ LA +L+ +L AE Sbjct: 4926 APDRAFQDLGLDSLTAIELRNLLGKATG--LRLPATTVFDYPTVDALAAHLLDELFGAE 4982 Score = 135 bits (339), Expect = 2e-28 Identities = 122/368 (33%), Positives = 167/368 (45%), Gaps = 30/368 (8%) Query: 3298 LITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKC--RIHTYAA 3354 LITGG G +G A +L ++ G ++L SRR P A+ + E +C ++ A Sbjct: 6360 LITGGTGGLGRSVARHLVSEHGVRSLLLVSRRGPAAEGVDAL--VAELAECGAQVTVEAC 6417 Query: 3355 DVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXX 3414 DV D VADL+AR R ++ + H AGVLDD ++ + PER L PK A + Sbjct: 6418 DVTDAVAVADLVARHR-----ISAVVHTAGVLDDGVVESLTPERLSAVLRPKVDAAWNLH 6472 Query: 3415 XXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ 3474 GQANYA NA LD L RRA GL A + +GPW Q Sbjct: 6473 EATRGLDLDAFVVFSSVAGTFGSAGQANYAAGNAFLDALAYHRRAVGLPAVSLAWGPWSQ 6532 Query: 3475 -GGMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAA-KVLG 3530 GGM S+A I QG+ PL L AL + A GS + L AA + G Sbjct: 6533 DGGMTGTLSDADVQRIARQGMPPLTVEEGL-ALFDA-ALGSAEPMALPVRLDLAALRAQG 6590 Query: 3531 SARPPILDLVLP----SAAGEATGDSE--LLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 +P + L+ +AA GD+ +L + + V ++ ++ L Sbjct: 6591 EPQPLLRGLIRTPGRRTAAAATEGDTAAAFAGRLTGLSAAEGREVVLGAVRSQIAGVLGH 6650 Query: 3585 ASPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 A FLDLG DSL A+ELRNRL + G + AT +FDYPT L +L + Sbjct: 6651 AEATEIDQDRAFLDLGFDSLTAVELRNRLGAVTG--IRLPATLLFDYPTPAELVAHLHAR 6708 Query: 3643 LPDAEAPE 3650 + APE Sbjct: 6709 I----APE 6712 >tr|Q3S869|Q3S869_9ACTO Tax_Id=42238 SubName: Full=Modular polyketide synthase;[Streptomyces neyagawaensis] Length = 5006 Score = 1587 bits (4109), Expect = 0.0 Identities = 1097/3013 (36%), Positives = 1506/3013 (49%), Gaps = 156/3013 (5%) Query: 9 EPTPSFAIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGK 66 +P AI+ + RFPG E W LL DG E +S +P DR W ++ + PDP PG Sbjct: 1622 DPDEPIAIVAMSCRFPGGIDTPERLWQLLVDGGEVLSGMPADRGWPLDRLYHPDPDHPGT 1681 Query: 67 VVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNT 126 R F+ D FD FFG+S RE MDPQ R+L+ET+W A E +GI P SL + T Sbjct: 1682 SYVREGSFLHDAGDFDPAFFGISPREAVAMDPQQRLLLETSWEAFERAGIDPASLRTTPT 1741 Query: 127 GVFVGLATHDYLGMASDELTYPEI-EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS 185 GVF G+ DY +A PE E ++ G + + +GR++Y LGL+GPAV VDTACS Sbjct: 1742 GVFAGVNYQDYTSLAGSS---PEGGEGHLVAGGAASVVSGRVAYTLGLEGPAVTVDTACS 1798 Query: 186 SSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGY 245 SSLVA H A QALR +C LALAGG V+ TP + FS LA DGRCK F A+ADG Sbjct: 1799 SSLVATHLAAQALRGGDCSLALAGGVAVMATPGVFVGFSRQRGLAADGRCKAFGASADGM 1858 Query: 246 VRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKR 305 EG GVV+++RL DA R+G + AV+RGSA+NQDGAS GL+ PNG+AQQRVI AL Sbjct: 1859 GLAEGVGVVLLERLSDARRNGHPVLAVLRGSAVNQDGASNGLSAPNGLAQQRVIRQALTN 1918 Query: 306 AGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXX 365 AGL ADV +EAHGTGT+LGDPIEA A G R PL +G+ K+NIGH + Sbjct: 1919 AGLTGADVDVVEAHGTGTTLGDPIEADALLATYGQDRPHGRPLWLGALKSNIGHTQAASG 1978 Query: 366 XXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFG 425 L + LP+ L+ + PSPH+ W +E++ E W G PR AG+SSFG Sbjct: 1979 VAGMIKTVLSLRHGVLPRTLHADEPSPHVDWASGEVELLTEARDWPDTGAPRRAGISSFG 2038 Query: 426 FAGTNAHVILEEAPAVG-------TPATTEPVEDPRRYSVLP-----LSARTPEALVRLA 473 F+GTN H ILE+AP T A P +PR P LSAR+P+AL A Sbjct: 2039 FSGTNVHAILEQAPPASDADADAETDADAGP--EPRHAPTAPVVPWVLSARSPQALTHQA 2096 Query: 474 GEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLV 533 R L D ++ T R E RA L+ ++ L LA PGL+ Sbjct: 2097 QRLRGHLAGGGAPDPLDTGYSLATGRTPFEHRAVLLGTGGDAPSAALDGLAGGEDTPGLI 2156 Query: 534 RGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFD 593 RG + + ++F GQG+Q+ GMA EL DT PVFA ++ C +A+ P +D D Sbjct: 2157 RGVADTDGRRVFVFPGQGAQWAGMAVELLDTSPVFAASMAACEQALT-----PYVDWSLD 2211 Query: 594 ADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVF 653 A P QPAL+AV + LA W+SWG EPD V+GHS G+ +AA VAG Sbjct: 2212 AVLRGAPDTPPFERVDVVQPALWAVMVSLAAQWRSWGVEPDAVLGHSQGEIAAAVVAGAL 2271 Query: 654 DVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPS-LSVAAYNGANTVL-S 711 ++DGA+++A R R +L G M +V ERA L + LS+AA NG + V+ S Sbjct: 2272 SLDDGAKVVALRSRAILALAGHGGMVSVAVPRERAVELVARWSGRLSLAAVNGPSAVVVS 2331 Query: 712 GPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDN 771 G + L +A DGVR + +A HSA ++ I + + + L Sbjct: 2332 GDTEALTELIAVCEEDGVRARTIAVDYASHSAHVERIRAEVLGALDGITPVAGRVPLYST 2391 Query: 772 RTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTAT------ 825 TG L +T +D YW R+ R+ VEF +VR LAD +V +E+ P PVLT + Sbjct: 2392 LTGDWLD-TTEMDAGYWYRNLRETVEFDGAVRALADQRHQVFVEVSPHPVLTMSVQETIE 2450 Query: 826 -ALAAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA--FRQPDARKLDL 882 A AA A V +LR + + A + G +P F AR+ DL Sbjct: 2451 SATAAESAEAPRTVVTGTLRRDEGGLARALTSAAELWVRG-VPVLWPVLFEGTGARRTDL 2509 Query: 883 PTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAV-----RLLEDGQIEELAALIDG 937 PTYPFEHR++W + +A S T T AV RL+E G E A + Sbjct: 2510 PTYPFEHRRYWLQ--------SAEPAAPSGTADETDAVDSAFWRLVERGDAAEAAGDL-- 2559 Query: 938 ETVDEQTL-RVLNKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILV---G 993 VD +TL VL L A +QR RY + W W++V G Sbjct: 2560 -AVDAETLGTVLPALNAWRRRQREGAAVDTWRYRVDWQPVPDPPAASLSGT-WLVVLPEG 2617 Query: 994 DDTAAVLEFA----DALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGD 1049 D A A ALT G V L +DAD A L + L A G ++ Sbjct: 2618 HDDAPGAPLARDSVTALTEAGADVVTVRLTDADADRATLGERLTTALEGRTPQGVLSLLA 2677 Query: 1050 GAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTV-VPEQSCL 1108 A P D V + L L +A D + +P+W T DTDT+ P+Q+ + Sbjct: 2678 IAGRPHPDHPAVSAGSALTLV-LVQALGDLGVEAPLWCATHGAVTTGDTDTLSAPDQALI 2736 Query: 1109 WGFGRAAALELPHIWGGLADLSGADTEWPR-LIARITSPRDGEDQIALRGDAVYAPRLVR 1167 WG G AALE P WGGL DL + R + I + GEDQ+A+R + RLVR Sbjct: 2737 WGTGMVAALEHPTRWGGLVDLPPSLNSLSRDRLRAILAGATGEDQLAVRSVGLLGRRLVR 2796 Query: 1168 RTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXX 1227 PS T + T LVTGG GA+G VA +LA GA H+VL RR Sbjct: 2797 AP-RPSGTRPAWKPRGTVLVTGGTGALGPHVARWLARGGAEHLVLPGRRGADVPGADELR 2855 Query: 1228 XXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEV 1287 + ++ + DVAD +A L+ + + P+ + HAA I L+ LDD + Sbjct: 2856 AELAELGTELSLPACDVADRDQIAGLLAGLEEQGTPVTAVFHAAAYI---QLASLDDTPL 2912 Query: 1288 D---RVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLA 1344 D V A K GA HL E L +LD FV SS+A VWG AY A NA+LD LA Sbjct: 2913 DAFAEVVAAKAEGARHLDELLD---RELDAFVLFSSVAGVWGSSNHAAYTAGNAYLDALA 2969 Query: 1345 WRLRERGVTAVSVNFGPWAAG-------MADAESRARLEQRGVRTLSPAEALAGMADVVA 1397 R RG++A +V++G W+A D R++++G+ + P ALAG+ + Sbjct: 2970 EHRRARGLSATTVDWGVWSAANPWAVRETVDESDFYRVQKQGLPLIEPDLALAGLQQALD 3029 Query: 1398 GPVQGV-VAKIDWSRFLPLYQQAGRRAFLS---ELESELXXXXXXXXXXXXXXXXXXLVE 1453 + +A +DW +F ++ L+ E +L L E Sbjct: 3030 DDETVIALANVDWEQFAAVFGSVRPSRLLTGVPEARRQLEEAATPGASAATPASDV-LRE 3088 Query: 1454 QLTKAPVQQRKSLITNYLRNAVAEVTRVDA-DEIRDEAGFFDLGMDSLMAVELRRRIEQG 1512 +LT +++ + + +R A V D+ +E+R F +LG DSL AVELR R+ Sbjct: 3089 RLTGLAEAEQRRVTLDLVRTHAAAVLGHDSPEELRPGRAFQELGFDSLTAVELRNRLRAA 3148 Query: 1513 VGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQ-ASTVTARTDDPIAVVAVSCRF 1571 G +P TLV D+P + AD++ EVLG R+ A TA D+PIA++A+SCRF Sbjct: 3149 TGLTLPATLVFDYPSAAVLADHIRAEVLGEHRTPATREPAPAGTAAADEPIAIIAMSCRF 3208 Query: 1572 PGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXX 1629 PG PE W LL G D + E P DR W ++ +DPDPD PG +Y R Sbjct: 3209 PGGVHTPEQLWRLLEEGGDVVSEFPTDRGWPLEAMFDPDPDQPGTSYVRHGGFLYDAGEF 3268 Query: 1630 XPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLL 1689 +FFGISPREAV ++PQQRL+LET WE ERAG P LRG+ TGVFTGV +Y Sbjct: 3269 DADFFGISPREAVAMDPQQRLLLETSWETFERAGLDPDRLRGTDTGVFTGVNYQDYG--A 3326 Query: 1690 SAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGD 1749 S + E H +TG+A + ISGR+++ LG EGPAV VDTACS++LVAVH A QAL++GD Sbjct: 3327 SVAQTQENEGHLLTGSAASVISGRISYTLGLEGPAVTVDTACSASLVAVHLAAQALRAGD 3386 Query: 1750 CDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDA 1809 C LALAGGV V+ SP +++ +R R L+ GRCK F +ADG +EG GV++L+RLS+A Sbjct: 3387 CSLALAGGVAVMSSPGAIISFARQRGLAADGRCKAFSDAADGMGMAEGVGVILLERLSEA 3446 Query: 1810 VRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTG 1869 R G V AV+ S+VNQDGAS+GLT PNG +QQR+I A LA A LS AD+D +E HGTG Sbjct: 3447 QRHGHPVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAALANARLSAADIDVVETHGTG 3506 Query: 1870 TPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLP 1929 T LGDPIE Q PLL+GS+K+NIGH ++A+G AG+IK VL+L+HG +P Sbjct: 3507 TRLGDPIEAQALLATYGQERSDGRPLLIGSLKSNIGHAQAAAGVAGVIKTVLALRHGQVP 3566 Query: 1930 QSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQL 1989 ++LH + PS + W A V V+ + PW GR RRAG+S+FG +GTN H +VE+AP Sbjct: 3567 RTLHVDRPSTQVDWTAGAVDVVTDTTPWPVTGRPRRAGISAFGMSGTNVHAIVEQAPEP- 3625 Query: 1990 HXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHT 2049 GT P LSA+SP+AL A R L+ TPGL AD+ Sbjct: 3626 -APEESPRDTPDEVPAGTVAWP----LSAKSPDALRGQAERLTAHLADTPGLPPADI-GR 3679 Query: 2050 AGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQY 2109 A R+ FE+RA LV D P +VRG T ++F GQGSQ+ Sbjct: 3680 ALTTRTAFEHRAVLVGDGTRLPAALTALADDGTAP-DLVRGVADTVGRTVFVFPGQGSQW 3738 Query: 2110 PGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFA 2169 GMAREL D PVFA + +C A+A + LLD + + QPALFA Sbjct: 3739 AGMARELLDESPVFAARMEECERALAPFVDWSLLDAV-----RSGSAWDRVDVVQPALFA 3793 Query: 2170 VEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGR 2229 V + LA +W+S+ + PD V+GHS G+ AAA VAG SL+DGA+++A R + +L G Sbjct: 3794 VMVSLAEVWRSFGVVPDAVVGHSQGEIAAAVVAGALSLEDGAQVVALRSKTLDALAGRGG 3853 Query: 2230 MVAVFADAEHV-EQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLA 2287 M ++ A+ E +A +SV A NGP TV++G E L ++ + E +G+R + Sbjct: 3854 MASLSLPADQAREALAPWAGALSVAALNGPATTVVAGDAEALAALLAQCEAQGVRARRID 3913 Query: 2288 TSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQP 2347 +A HSE ++ + +PL G L T + A YW R+ RQ Sbjct: 3914 VDYASHSEHVEEIHGILMDALAGIKPLPSEVPLYSTVDGGWL-DTTGMHAGYWYRNLRQT 3972 Query: 2348 VQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIAD 2407 V F +VR +AA G + +E+ P PVLT A + + +LR+ R++ Sbjct: 3973 VGFDPAVRVLAAEGFTSFVEVSPHPVLTMAIEETTETAGREAVVLGTLRRDEGGLRRVLL 4032 Query: 2408 ALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDG-GTAASGILGSG 2466 + A +V G D+ A ELPTY FQRRR+W + + G G +LG+ Sbjct: 4033 SAAELWVRGGAVDWTAAF-PGESTAELPTYAFQRRRYWIQPPAATPRGPGATGHPLLGTA 4091 Query: 2467 KDLA-SGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPA---RLKDVF 2522 ++A +GD + + LS ++ PWLADH + G V++PG + +A+ A G A R++++ Sbjct: 4092 VEVADTGDLVLSGSLSTRTHPWLADHAVSGVVLLPGTGFVELAVRA-GDEADCPRVEELT 4150 Query: 2523 FYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGS-DP 2581 P++ A+ ++Q+ + D + + SR G W+ +A G + AGS DP Sbjct: 4151 LQAPLVFDRDAAVQIQVRVGAPDESGRRTLGVFSRGEDGAGTPWTGHATGVLAPAGSTDP 4210 Query: 2582 DAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDIL 2641 A + P E + L+E FAD +GP + G L + W + ++ Sbjct: 4211 AAHPYGAAWPP----AGAEPVSVDGLYERFADAGYGYGPAFHG-LHAAWRLGQDVYVEVR 4265 Query: 2642 VGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPR 2701 + +L +HP L+D LP + V L Sbjct: 4266 LPEDLHTGAAGFGLHPALLDAALHGLWLAAPEGADQNDEPGTARLPFSWEGVRLHASGAT 4325 Query: 2702 RFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLL 2761 R + +T L D GR + + ++ +A LRG L Sbjct: 4326 ELRVRLSY------DDTGSVALSAADPAGRPVADVAALAIRPIAVDA-LRGAAAQGRDSL 4378 Query: 2762 YTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGA 2821 +TLGW + P + + VG W G + L + N D L+ A A Sbjct: 4379 FTLGWTAL--PATTEPPVGRWAALGTEHLLPET------HENLD------ALTAAVDGDA 4424 Query: 2822 GFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHGV 2881 VV PG + L+ A V +VT GV Sbjct: 4425 AVPDVVVTLCPPGGNSADAARTALAATLRLLQTWLADDRWADTRLV-------LVTRGGV 4477 Query: 2882 ACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPE 2940 A GE + D AA+WG R+ +E P LVD + +EA+ EP+ Sbjct: 4478 ATARGEDIGDLAAAAVWGLVRSAQSEHPDRFV-LVDAEDPAEALKALPAAL---SATEPQ 4533 Query: 2941 IAVRQGKLLASRL 2953 +AVR G+ LA RL Sbjct: 4534 LAVRDGRTLAPRL 4546 Score = 1459 bits (3778), Expect = 0.0 Identities = 964/2535 (38%), Positives = 1302/2535 (51%), Gaps = 131/2535 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 A++ + FPG S E+ W L+ DGR+ S +P DR WD G V Sbjct: 39 AVVAMSCHFPGGVHSPEDLWELVADGRDTYSGIPADRGWDTT-------GLAGSGVPVTG 91 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 F+D+ GFD FFG+S RE MDPQ R++++T W AVE GI P SL S TGVF Sbjct: 92 AFLDEAGGFDPAFFGISPREALAMDPQQRLMLQTCWEAVERGGIDPVSLRGSRTGVFAAS 151 Query: 133 ATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 Y+ +A PE ++ ++ G + + +GR+SY +GL+GP+V VDTACS+SLVA+ Sbjct: 152 IDQGYMSLADGA---PEGVQGFLMTGNAISVMSGRVSYVMGLEGPSVTVDTACSASLVAL 208 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A Q+LR +EC LAL GG NV+ P + S LA DGR K F AAADG GEG Sbjct: 209 HLAAQSLRNDECSLALVGGVNVMALPGAFVEISRQGGLAADGRSKPFAAAADGTGWGEGV 268 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 GV++V+RL DA +G + AV+RGSAINQDGAS GLT PNG +QQRVI AL A L PA Sbjct: 269 GVLLVERLSDARANGHPVLAVLRGSAINQDGASNGLTAPNGPSQQRVIRAALADAQLAPA 328 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT LGDPIEA A G RA ++PL +GS K+NIGH + Sbjct: 329 DVDAVEAHGTGTRLGDPIEADALLAAYGQDRAEDQPLWLGSIKSNIGHTQAAAGLAGVIK 388 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 + + LP+ L+ + P+PH+ W + ++ E W G+PR AGVSSFG +GTNA Sbjct: 389 VVMAIRHGVLPQTLHVDAPTPHVDWSSGGVRLLTERRDWPVAGRPRRAGVSSFGMSGTNA 448 Query: 432 HVIL------------EEAPAVGTPATTEPVE----------------------DPRRYS 457 HVI+ E+AP G EP+ DP Sbjct: 449 HVIIEQASEAEQRPAAEQAPEGGRQGAAEPIAGAGPRTAPDAGSGVASGSASGVDPLPTV 508 Query: 458 VLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAI 517 PLS R+PEAL A WL P R ADV H+ T R+ E RA +V + E + Sbjct: 509 PWPLSGRSPEALRDQAARLASWLADRPGLRPADVGHSLATTRSAFEHRAVVVADRPEGFL 568 Query: 518 ELLGALADDRPAPGLVRGESHEAP-KTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCA 576 L A+A A V G + +T ++F GQGSQ+ GMAR+L D PVFA + +C Sbjct: 569 RGLAAVAAGTSAAETVSGRTGAGDGRTVFVFPGQGSQWAGMARQLLDESPVFAARMAECE 628 Query: 577 EAVADILEKPLLDVIFDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVV 636 +A+A P LD A +PL QP LFAV + LA +W+S+G EPD V Sbjct: 629 QALA-----PHLDWSLSAVVRGEPDAAPLDRIDVVQPVLFAVMVSLAAVWRSYGVEPDAV 683 Query: 637 VGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAV-FTAPERAERLTDEY 695 VGHS G+ +AA VAG ++D AR++A R R L G MA+V A E L Sbjct: 684 VGHSQGEIAAAYVAGALSLDDAARIVAVRSRAQLGLSGTGGMASVALPADTLRESLCAWE 743 Query: 696 PSLSVAAYNG-ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFES 754 LSVAA NG A+ V+SG + LE + VR + A HSA +D + D Sbjct: 744 GRLSVAAVNGPASAVVSGDPEALEEFLRQCEEREVRTRRVAADVAGHSAHMDRLRDGMLD 803 Query: 755 FAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLL 814 + TG +L +T LD YW R+ RQ VEF +VR L V + Sbjct: 804 ALADVRPTAATIPFCSTVTGGSLD-TTGLDAGYWFRNMRQTVEFDAAVRDLVRRGHSVFV 862 Query: 815 EIGPRPVLTATALAAWPD--------PATTPQVLASLRPTTADHRQITEAVAAAYAAGHL 866 EI P PVLT D PA V +LR ++ A+A + G Sbjct: 863 EISPHPVLTVPTQDTLDDLADPDAAVPAPPTLVTGTLRRDEGGLHRVLTALAQVHVHGVP 922 Query: 867 PDFRA-FRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLED 925 D+ A F +++LPTY F++R+FW +TA P +E Sbjct: 923 VDWTAVFAGHRPERVELPTYAFQNRRFWLEPQTRPGTAPETAD-----PADAAFWAAVER 977 Query: 926 GQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXX 985 + +AA + E +L L+A +R V RY I W Sbjct: 978 EDVAAVAATLGVEAASWSD--ILPALSAWRRDRRDRAVLDGWRYHISWQRLTAKTAGPLR 1035 Query: 986 XXDWILVGDD---TAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYV 1042 +LV D AAV +AL G ++V L + D ++L D LR Sbjct: 1036 GRWPVLVPDGHTADAAVTRAVEALRERGANPELVVLDHTHTDRSRLTDHLREL------- 1088 Query: 1043 VHIAAGDG---AAAPMRDLLRVQHRTLGGL----------RRLFRAANDAELRSPIWLVT 1089 +A G G A + + LL + R GL L +A +D ++R+ +W T Sbjct: 1089 --LATGPGTETAPSGVLSLLALDERPHEGLPALPVGLALTTALVQALDDLDVRTTLWCAT 1146 Query: 1090 RDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADL-SGADTEWPRLIARITSPR 1147 V ++ V P Q+ +WGFGR AALE P +WGGL DL D L+ + + Sbjct: 1147 SGAVPVHPSEPVPHPVQALVWGFGRTAALEHPSLWGGLIDLPEQCDERAGHLLGDLLAGA 1206 Query: 1148 DGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGA 1207 EDQ+A+R +A RLVR T S P R T LVTGG G +G A +LA GA Sbjct: 1207 GDEDQLAIRASGAHARRLVRATPSTSAPSAPWRPSGTVLVTGGTGGLGAHAARWLARGGA 1266 Query: 1208 GHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGI 1267 H+VL SRR V + D+ D +A L+ VAA+ P+ + Sbjct: 1267 DHLVLVSRRGADAPGADELAAELTALGTGVTLAACDITDREALAALVDRVAADGHPVRAV 1326 Query: 1268 VHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGG 1327 +H A P+ + A + A KV GA +L L D TDLD FV SS++ VWG Sbjct: 1327 LHTAAAAQLFPVRDENPASMAATLAAKVQGAANLDAVLAD--TDLDAFVLYSSVSGVWGS 1384 Query: 1328 FGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAA---GMADAESRARLEQRGVRTLS 1384 AY A NA+LD LA R RG+ A SV +G W+A G+A ++ L +RG+ + Sbjct: 1385 ADHAAYAAGNAYLDALAAHRRGRGLAATSVVWGIWSAEGGGLATSDLERALLERGIPFMD 1444 Query: 1385 PAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSE------LESELXXXXX 1437 P A+ G+ V+ VVA +DW+RF+P++ +++ L + Sbjct: 1445 PRLAVGGLQRVLDDDETVVVVADVDWARFVPVFTSVRPSPLIADLPDVRALATAEDRTEP 1504 Query: 1438 XXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGM 1497 + LT+ V R++L+ NA A + AD + + F +LG Sbjct: 1505 DPGDTDGASALRRTLAGLTEPEV--RRTLLELVRTNAAAVLGHESADAVLPDRAFRELGF 1562 Query: 1498 DSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTAR 1557 DSL+AVELR R+ Q G + T+V D+ + A++L E+LG A A Sbjct: 1563 DSLIAVELRNRLNQVTGLRLRATVVFDYSCAALLAEHLRTELLGDTAPAAAPAAVVPVAD 1622 Query: 1558 TDDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKT 1615 D+PIA+VA+SCRFPG D PE W+LL G + + +P DR W +D Y PDPD PG + Sbjct: 1623 PDEPIAIVAMSCRFPGGIDTPERLWQLLVDGGEVLSGMPADRGWPLDRLYHPDPDHPGTS 1682 Query: 1616 YTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTG 1675 Y R P FFGISPREAV ++PQQRL+LET WE ERAG P+ LR + TG Sbjct: 1683 YVREGSFLHDAGDFDPAFFGISPREAVAMDPQQRLLLETSWEAFERAGIDPASLRTTPTG 1742 Query: 1676 VFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSAL 1735 VF GV +Y L+ S + E H + G A + +SGRVA+ LG EGPAV VDTACSS+L Sbjct: 1743 VFAGVNYQDYTS-LAGSSPEGGEGHLVAGGAASVVSGRVAYTLGLEGPAVTVDTACSSSL 1801 Query: 1736 VAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRS 1795 VA H A QAL+ GDC LALAGGV V+ +P V SR R L+ GRCK F ASADG + Sbjct: 1802 VATHLAAQALRGGDCSLALAGGVAVMATPGVFVGFSRQRGLAADGRCKAFGASADGMGLA 1861 Query: 1796 EGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGL 1855 EG GV++L+RLSDA R+G V AV+ S+VNQDGAS+GL+ PNG AQQR+I L AGL Sbjct: 1862 EGVGVVLLERLSDARRNGHPVLAVLRGSAVNQDGASNGLSAPNGLAQQRVIRQALTNAGL 1921 Query: 1856 SGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAG 1915 +GADVD +EAHGTGT LGDPIE PL +G++K+NIGHT++ASG AG Sbjct: 1922 TGADVDVVEAHGTGTTLGDPIEADALLATYGQDRPHGRPLWLGALKSNIGHTQAASGVAG 1981 Query: 1916 LIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTG 1975 +IK VLSL+HGVLP++LH + PSPH+ W + V ++ E W G RRAG+SSFGF+G Sbjct: 1982 MIKTVLSLRHGVLPRTLHADEPSPHVDWASGEVELLTEARDWPDTGAPRRAGISSFGFSG 2041 Query: 1976 TNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL--ALSARSPEALVELARRYDD 2033 TN H ++E+APP + V+ LSARSP+AL A+R Sbjct: 2042 TNVHAILEQAPPASDADADAETDADAGPEPRHAPTAPVVPWVLSARSPQALTHQAQRLRG 2101 Query: 2034 WLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHV 2093 L+ D D ++ GR+ FE+RA L+ G++RG Sbjct: 2102 HLAGGGAPDPLDTGYSLATGRTPFEHRAVLLGTGGDAPSAALDGLAGGEDTPGLIRGVAD 2161 Query: 2094 HRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET 2153 ++F GQG+Q+ GMA EL DT PVFA ++ C +A+ + LD + +T Sbjct: 2162 TDGRRVFVFPGQGAQWAGMAVELLDTSPVFAASMAACEQALTPYVDWS-LDAVLRGAPDT 2220 Query: 2154 ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARL 2213 + QPAL+AV + LA W+SW +EPD VLGHS G+ AAA VAG SLDDGA++ Sbjct: 2221 PP-FERVDVVQPALWAVMVSLAAQWRSWGVEPDAVLGHSQGEIAAAVVAGALSLDDGAKV 2279 Query: 2214 MAERGRMFGSLPEGGRMVAVFADAEH-VEQVAGEFPRVSVGAYNGPN-TVLSGPGEDLEE 2271 +A R R +L G MV+V E VE VA R+S+ A NGP+ V+SG E L E Sbjct: 2280 VALRSRAILALAGHGGMVSVAVPRERAVELVARWSGRLSLAAVNGPSAVVVSGDTEALTE 2339 Query: 2272 IVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTG 2331 ++ E++G+R +A +A HS ++ + +PL TG L Sbjct: 2340 LIAVCEEDGVRARTIAVDYASHSAHVERIRAEVLGALDGITPVAGRVPLYSTLTGDWL-D 2398 Query: 2332 QTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ-----VWPEHM 2386 T +DA YW R+ R+ V+F +VR +A V +E+ P PVLT + + E Sbjct: 2399 TTEMDAGYWYRNLRETVEFDGAVRALADQRHQVFVEVSPHPVLTMSVQETIESATAAESA 2458 Query: 2387 AAPRAV--ASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRR 2443 APR V +LR+ + + A +V G + + R +LPTYPF+ RR Sbjct: 2459 EAPRTVVTGTLRRDEGGLARALTSAAELWVRGVPVLWPVLFEGTGARRTDLPTYPFEHRR 2518 Query: 2444 FWPKASSIAVDGGTA 2458 +W +++ A GTA Sbjct: 2519 YWLQSAEPAAPSGTA 2533 Score = 620 bits (1598), Expect = e-174 Identities = 408/1004 (40%), Positives = 534/1004 (53%), Gaps = 69/1004 (6%) Query: 1533 DYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAI 1591 DYL + L Q R+ V R+ +PIAVVA+SC FPG PE WEL+A G D Sbjct: 11 DYLNRVTIDL--QQTRRRLRDVEERSREPIAVVAMSCHFPGGVHSPEDLWELVADGRDTY 68 Query: 1592 REVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRL 1650 +P DR WD G P FFGISPREA+ ++PQQRL Sbjct: 69 SGIPADRGWDTTGLAGSGVPVTGAFLDEAGGFD-------PAFFGISPREALAMDPQQRL 121 Query: 1651 MLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAI 1710 ML+T WE +ER G P LRGSRTGVF Y L + ++ +TGNA++ + Sbjct: 122 MLQTCWEAVERGGIDPVSLRGSRTGVFAASIDQGYMSLADGAP-EGVQGFLMTGNAISVM 180 Query: 1711 SGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAA 1770 SGRV++ +G EGP+V VDTACS++LVA+H A Q+L++ +C LAL GGVNV+ P V Sbjct: 181 SGRVSYVMGLEGPSVTVDTACSASLVALHLAAQSLRNDECSLALVGGVNVMALPGAFVEI 240 Query: 1771 SRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGA 1830 SR L+ GR K F A+ADG EG GVL+++RLSDA +G V AV+ S++NQDGA Sbjct: 241 SRQGGLAADGRSKPFAAAADGTGWGEGVGVLLVERLSDARANGHPVLAVLRGSAINQDGA 300 Query: 1831 SSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXX 1890 S+GLT PNG +QQR+I A LA A L+ ADVD +EAHGTGT LGDPIE Sbjct: 301 SNGLTAPNGPSQQRVIRAALADAQLAPADVDAVEAHGTGTRLGDPIEADALLAAYGQDRA 360 Query: 1891 XXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRV 1950 PL +GS+K+NIGHT++A+G AG+IKVV++++HGVLPQ+LH + P+PH+ W + VR+ Sbjct: 361 EDQPLWLGSIKSNIGHTQAAAGLAGVIKVVMAIRHGVLPQTLHVDAPTPHVDWSSGGVRL 420 Query: 1951 IDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQ---------------------- 1988 + E W GR RRAGVSSFG +GTNAHV++E+A Sbjct: 421 LTERRDWPVAGRPRRAGVSSFGMSGTNAHVIIEQASEAEQRPAAEQAPEGGRQGAAEPIA 480 Query: 1989 ---LHXXXXXXXXXXXXXXXGTDDSPQV-LALSARSPEALVELARRYDDWLSATPGLDIA 2044 G D P V LS RSPEAL + A R WL+ PGL A Sbjct: 481 GAGPRTAPDAGSGVASGSASGVDPLPTVPWPLSGRSPEALRDQAARLASWLADRPGLRPA 540 Query: 2045 DVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGE-HVHRPTTAWLFT 2103 DV H+ RS FE+RA +V D + A V G T ++F Sbjct: 541 DVGHSLATTRSAFEHRAVVVADRPEGFLRGLAAVAAGTSAAETVSGRTGAGDGRTVFVFP 600 Query: 2104 GQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFA 2163 GQGSQ+ GMAR+L D PVFA + +C +A+A L L V+ A L Sbjct: 601 GQGSQWAGMARQLLDESPVFAARMAECEQALAPHLDWSLSAVV--RGEPDAAPLDRIDVV 658 Query: 2164 QPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGS 2223 QP LFAV + LA +W+S+ +EPD V+GHS G+ AAA VAG SLDD AR++A R R Sbjct: 659 QPVLFAVMVSLAAVWRSYGVEPDAVVGHSQGEIAAAYVAGALSLDDAARIVAVRSRAQLG 718 Query: 2224 LPEGGRMVAVFADAEHV-EQVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGI 2281 L G M +V A+ + E + R+SV A NGP + V+SG E LEE + + E+ + Sbjct: 719 LSGTGGMASVALPADTLRESLCAWEGRLSVAAVNGPASAVVSGDPEALEEFLRQCEEREV 778 Query: 2282 RCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWR 2341 R +A A HS +D + D T+P TG L T LDA YW Sbjct: 779 RTRRVAADVAGHSAHMDRLRDGMLDALADVRPTAATIPFCSTVTGGSL-DTTGLDAGYWF 837 Query: 2342 RHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRA---------V 2392 R+ RQ V+F +VR + G SV +EI P PVLT Q + +A P A Sbjct: 838 RNMRQTVEFDAAVRDLVRRGHSVFVEISPHPVLT-VPTQDTLDDLADPDAAVPAPPTLVT 896 Query: 2393 ASLRKGVADRRQIADALASAYVGGHRPDFAAV---HRQPRRPVELPTYPFQRRRFW---- 2445 +LR+ ++ ALA +V G D+ AV HR R VELPTY FQ RRFW Sbjct: 897 GTLRRDEGGLHRVLTALAQVHVHGVPVDWTAVFAGHRPER--VELPTYAFQNRRFWLEPQ 954 Query: 2446 --PKASSIAVDGGTAASGILGSGKDLASGDTIYTSRLSVKSQPW 2487 P + D AA +D+A+ + L V++ W Sbjct: 955 TRPGTAPETADPADAAFWAAVEREDVAA----VAATLGVEAASW 994 Score = 139 bits (349), Expect = 1e-29 Identities = 112/372 (30%), Positives = 158/372 (42%), Gaps = 20/372 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG G +G H A +LA+ GA +VL SRR D + + A D+ Sbjct: 1245 LVTGGTGGLGAHAARWLARGGADHLVLVSRRGADAPGADELAAELTALGTGVTLAACDIT 1304 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A L+ R+ A+ P+ + H A + +NP TLA K GA++ Sbjct: 1305 DREALAALVDRVAADGHPVRAVLHTAAAAQLFPVRDENPASMAATLAAKVQGAANLDAVL 1364 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ--G 3475 A YA NA LD L A RR +GL AT + +G W G Sbjct: 1365 ADTDLDAFVLYSSVSGVWGSADHAAYAAGNAYLDALAAHRRGRGLAATSVVWGIWSAEGG 1424 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP 3535 G+A+S+ A + +G+ +DP A+ L V+ + V +W R V S RP Sbjct: 1425 GLATSDLERA-LLERGIPFMDPRLAVGGLQRVLDDDETVVVVADVDWARFVPVFTSVRPS 1483 Query: 3536 ILDLVLPSA-------------AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL 3582 L LP G+ G S L + L + P+ + E ++ L Sbjct: 1484 PLIADLPDVRALATAEDRTEPDPGDTDGASALRRTLAGLTEPEVRRTLLELVRTNAAAVL 1543 Query: 3583 RLASPPAA--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV 3640 S A F +LG DSL+A+ELRNRL+ G + AT VFDY LAE+L Sbjct: 1544 GHESADAVLPDRAFRELGFDSLIAVELRNRLNQVTG--LRLRATVVFDYSCAALLAEHLR 1601 Query: 3641 GQLPDAEAPETA 3652 +L AP A Sbjct: 1602 TELLGDTAPAAA 1613 Score = 130 bits (327), Expect = 4e-27 Identities = 139/478 (29%), Positives = 197/478 (41%), Gaps = 36/478 (7%) Query: 1076 ANDAELRSPIWLVTRDGQRVTDTDTVVP-EQSCLWGFGRAAALELPHIWGGLADLSGADT 1134 A+D + + LVTR G + + + +WG R+A E P + L D Sbjct: 4460 ADDRWADTRLVLVTRGGVATARGEDIGDLAAAAVWGLVRSAQSEHPDRFV-LVDAEDPAE 4518 Query: 1135 EWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPL----PVREDRTYLVTGG 1190 L A +++ E Q+A+R APRL R P+D P + T LVTG Sbjct: 4519 ALKALPAALSAT---EPQLAVRDGRTLAPRLTRTP--PTDAEAVAGKPWDPEGTVLVTGA 4573 Query: 1191 LGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHD 1249 G +G VA +L + HG H++LT RR V D AD Sbjct: 4574 FGVLGGLVARHLVTEHGVRHLLLTGRRGADTPEATALVDELTALGARVETAACDTADRDA 4633 Query: 1250 VARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLR 1309 +A L+ V + PL +VH+AG + + L +D V K A +L E DL Sbjct: 4634 LAGLLAGVP-DTHPLTAVVHSAGVLDDGVIGSLTPERLDHVLRPKADAALNLHELTRDL- 4691 Query: 1310 TDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-----A 1364 L FV SS + G GQ Y AANAFLD LA R +G+ A S+ +G WA Sbjct: 4692 -PLAAFVLFSSASGTVGSSGQGNYAAANAFLDALAQHRRAQGLPAQSIAWGMWAERSTLT 4750 Query: 1365 GMADAESRARLEQRGVRTLSPAEALA------GMADVVAGPVQGVVAKIDWSRFLPLYQQ 1418 G D R+ + GV L+ E LA D V PV ++D +R L + Sbjct: 4751 GTLDEVDLRRIARGGVGALTSDEGLALFDAALERDDAVLVPV-----RLDLAR---LRSR 4802 Query: 1419 AGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVE-QLTKAPVQQRKSLITNYLRNAVAE 1477 AG A + S + + +L ++++ + + A+ Sbjct: 4803 AGTGAVPALFRSLVRGAARRTAATGGAADAADTLRGRLAGLAADDARAVLADLVCAHAAD 4862 Query: 1478 VT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADY 1534 V A + E F LG DSL AVELR R+ G +P TLV D+P + A Y Sbjct: 4863 VLGHAGASAVDPERAFRQLGFDSLTAVELRNRLNAATGLRLPATLVFDYPSPAAVAGY 4920 Score = 129 bits (325), Expect = 7e-27 Identities = 106/361 (29%), Positives = 155/361 (42%), Gaps = 22/361 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA+ GA +VL RR D + + A DV Sbjct: 2814 LVTGGTGALGPHVARWLARGGAEHLVLPGRRGADVPGADELRAELAELGTELSLPACDVA 2873 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D Q+A LLA + + P+ + H A + A L + F +A KA GA H Sbjct: 2874 DRDQIAGLLAGLEEQGTPVTAVFHAAAYIQLASLDDTPLDAFAEVVAAKAEGARH-LDEL 2932 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG- 3476 A Y NA LD L RRA+GL AT +++G W Sbjct: 2933 LDRELDAFVLFSSVAGVWGSSNHAAYTAGNAYLDALAEHRRARGLSATTVDWGVWSAANP 2992 Query: 3477 ----MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA 3532 E+ + QGL ++P AL L + + + + +W++ A V GS Sbjct: 2993 WAVRETVDESDFYRVQKQGLPLIEPDLALAGLQQALDDDETVIALANVDWEQFAAVFGSV 3052 Query: 3533 RPPILDLVLPSA-----------AGEATGDSELLKQ-LMEIPIPQRAGFVTEFLQREVQN 3580 RP L +P A A AT S++L++ L + ++ + ++ Sbjct: 3053 RPSRLLTGVPEARRQLEEAATPGASAATPASDVLRERLTGLAEAEQRRVTLDLVRTHAAA 3112 Query: 3581 FLRLASPP--AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEY 3638 L SP F +LG DSL A+ELRNRL + G T+ AT VFDYP+ LA++ Sbjct: 3113 VLGHDSPEELRPGRAFQELGFDSLTAVELRNRLRAATG--LTLPATLVFDYPSAAVLADH 3170 Query: 3639 L 3639 + Sbjct: 3171 I 3171 Score = 122 bits (307), Expect = 8e-25 Identities = 110/370 (29%), Positives = 150/370 (40%), Gaps = 19/370 (5%) Query: 3298 LITGGLGAIGLHTAAYLA-QLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHTYAAD 3355 L+TG G +G A +L + G ++LT RR D A +DE+T R+ T A D Sbjct: 4569 LVTGAFGVLGGLVARHLVTEHGVRHLLLTGRRGADTPEATALVDELTALG-ARVETAACD 4627 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 D +A LLA + + PL + H AGVLDD ++ + PER L PKA A + Sbjct: 4628 TADRDALAGLLAGV-PDTHPLTAVVHSAGVLDDGVIGSLTPERLDHVLRPKADAALNLHE 4686 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQ NYA ANA LD L RRAQGL A I +G W + Sbjct: 4687 LTRDLPLAAFVLFSSASGTVGSSGQGNYAAANAFLDALAQHRRAQGLPAQSIAWGMWAER 4746 Query: 3476 GMAS---SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA 3532 + E I G+ L L + ++ + R G+ Sbjct: 4747 STLTGTLDEVDLRRIARGGVGALTSDEGLALFDAALERDDAVLVPVRLDLARLRSRAGTG 4806 Query: 3533 RPPIL--DLVLPSA------AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 P L LV +A G A L +L + + + + + L Sbjct: 4807 AVPALFRSLVRGAARRTAATGGAADAADTLRGRLAGLAADDARAVLADLVCAHAADVLGH 4866 Query: 3585 ASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 A A F LG DSL A+ELRNRL++ G + AT VFDYP+ +A Y + Sbjct: 4867 AGASAVDPERAFRQLGFDSLTAVELRNRLNAATG--LRLPATLVFDYPSPAAVAGYCAER 4924 Query: 3643 LPDAEAPETA 3652 L A P A Sbjct: 4925 LAPAGTPPAA 4934 Score = 48.5 bits (114), Expect = 0.020 Identities = 44/143 (30%), Positives = 55/143 (38%), Gaps = 20/143 (13%) Query: 2873 LWIVTEHGVACESGEPVD-PVQAALWGFGRTTINEEPALHCRLVDC-DGSSEAVDXXXXX 2930 LW T V EPV PVQA +WGFGRT E P+L L+D + E Sbjct: 1142 LWCATSGAVPVHPSEPVPHPVQALVWGFGRTAALEHPSLWGGLIDLPEQCDERAGHLLGD 1201 Query: 2931 XXXPGIQEPEIAVRQGKLLASRLL-----------PWARSGHLTLPRG----GDFVLAPT 2975 E ++A+R A RL+ PW SG + + G G Sbjct: 1202 LLAGAGDEDQLAIRASGAHARRLVRATPSTSAPSAPWRPSGTVLVTGGTGGLGAHAARWL 1261 Query: 2976 ERGAIDNLRLTE---TDVPEPDE 2995 RG D+L L D P DE Sbjct: 1262 ARGGADHLVLVSRRGADAPGADE 1284 Score = 45.8 bits (107), Expect = 0.13 Identities = 85/314 (27%), Positives = 107/314 (34%), Gaps = 55/314 (17%) Query: 2762 YTLGWHEVPPPPSADDAVGTWLIA---GFD----------------ELAAKVPGCVPIDR 2802 Y + W VP PP+A + GTWL+ G D E A V D Sbjct: 2591 YRVDWQPVPDPPAASLS-GTWLVVLPEGHDDAPGAPLARDSVTALTEAGADVVTVRLTDA 2649 Query: 2803 NTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAA 2862 + D LGE L+ A G GV+ A GR + V A Sbjct: 2650 DADRATLGERLTTA-LEGRTPQGVLSLLAIAGRPHPDHPAVSAGSALTLVL-----VQAL 2703 Query: 2863 QGPSVKLPGGLWIVTEHGVACESGEPVD-PVQAALWGFGRTTINEEPALHCRLVDCDGSS 2921 V+ P LW T V + + P QA +WG G E P LVD S Sbjct: 2704 GDLGVEAP--LWCATHGAVTTGDTDTLSAPDQALIWGTGMVAALEHPTRWGGLVDLPPSL 2761 Query: 2922 EAVDXXXXXXXXPGIQ-EPEIAVRQGKLLASRLL----------PWARSGHLTLPRGGDF 2970 ++ G E ++AVR LL RL+ W G L GG Sbjct: 2762 NSLSRDRLRAILAGATGEDQLAVRSVGLLGRRLVRAPRPSGTRPAWKPRG-TVLVTGGTG 2820 Query: 2971 VLAP-----TERGAIDNLRL---TETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGD 3022 L P RG ++L L DVP DE +R E A L L++ D Sbjct: 2821 ALGPHVARWLARGGAEHLVLPGRRGADVPGADE----LRAELAELGTE--LSLPACDVAD 2874 Query: 3023 PGPIGGDFAGTVTQ 3036 I G AG Q Sbjct: 2875 RDQIAGLLAGLEEQ 2888 >tr|B6ZIR3|B6ZIR3_STRPT Tax_Id=58346 (pldAII)SubName: Full=Polyketide synthase;[Streptomyces platensis] Length = 7026 Score = 1583 bits (4099), Expect = 0.0 Identities = 1093/3029 (36%), Positives = 1528/3029 (50%), Gaps = 166/3029 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G A R+PG S E+ W L+ DGR+AISD P DR W++E + PDP PG TR Sbjct: 3665 AIVGMACRYPGGVESPEDLWQLVADGRDAISDFPADRGWNVESLYHPDPDHPGTSYTRAG 3724 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FD FFG+S RE DPQ R+L+ET+W A+E +GI P++L + TGVF+G+ Sbjct: 3725 GFLHDAADFDPEFFGISPREALATDPQQRLLLETSWEAMERAGINPSTLKGTPTGVFLGV 3784 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 +DY G A + E +MA G++ + A+GR+SY GL+GPAV VDTACSSSLVA+H Sbjct: 3785 MYNDY-GTAMQQAA-EVFEGHMASGSAGSVASGRVSYTFGLEGPAVTVDTACSSSLVALH 3842 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR EC LALAGG V+ TPAT + FS LA DGRCK F AADG GEG G Sbjct: 3843 LAAQALRNGECTLALAGGVAVMSTPATFVEFSRQRGLAADGRCKAFADAADGTGWGEGVG 3902 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V++V+RL DA R+G + AV+ GSA+NQDGAS GLT PNG +QQRVI AL AGL AD Sbjct: 3903 VLLVERLSDARRNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIQQALANAGLAGAD 3962 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R+ + PL +GS K+NIGH + Sbjct: 3963 VDAVEAHGTGTRLGDPIEAQALIATYGQARSADRPLWLGSLKSNIGHTQAAAGVAGVIKM 4022 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 +++ TLP L+ + P+ + W +E++ E VPW + +PR VSSFG +GTNAH Sbjct: 4023 VQAMQHGTLPPTLHIDQPTGQVDWATGAVELLTEAVPWPDSDRPRRVAVSSFGVSGTNAH 4082 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLP-----------------LSARTPEALVRLAGE 475 VI+E P TP TT R +LP LSA+T +AL A Sbjct: 4083 VIIEHTPH--TPHTT------RTCPILPIPPGPADCAGPSAGAWLLSAKTSQALAAQARR 4134 Query: 476 YRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRG 535 LRA+P R ADV+H+ T R+ +RA + R+ A+ L ALAD PAP LV+G Sbjct: 4135 LSAHLRANPDLRSADVAHSLLTTRSVHAERAVFIAGDRDEALAALDALADGTPAPHLVQG 4194 Query: 536 ESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD 595 + + KT ++F GQGSQ+ GMA EL D VFAE + CA A+ ++ L DV+ D Sbjct: 4195 LADVSGKTVFVFPGQGSQWVGMAVELLDGSEVFAEHMAACARALEPFVDWSLEDVLRQTD 4254 Query: 596 ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDV 655 PL QP L+AV + LA LWQ+ G EP V+GHS G+ +AACVAG + Sbjct: 4255 GT-----WPLERVEVVQPVLWAVMVSLAGLWQAHGVEPAAVLGHSQGEIAAACVAGALSL 4309 Query: 656 EDGARLIAERGRLFGSLPAG--GRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVL-SG 712 EDGAR++A R + AG G ++ A + A + +S+A NG ++V+ +G Sbjct: 4310 EDGARVVALRSQAIAETLAGHGGMLSIAAPATDIAPLIARWNERISIATVNGPHSVVVAG 4369 Query: 713 PAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNR 772 LE+ L G+R + +A H+ ++ I + + ++ R ++ Sbjct: 4370 DPDALEALRGELETRGLRNRRIPVDYASHTPHVEAIRERLLADLAVIQPRAASIPVLSTV 4429 Query: 773 TGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPD 832 TG+ L +T +D YW R+ RQ VEF + RTL D + R +EI P PVLT + Sbjct: 4430 TGAWLD-TTVMDAEYWYRNLRQTVEFEAATRTLLDQDHRYFVEISPHPVLTIGLQQTIEE 4488 Query: 833 PATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFR-AFRQPDARKLDLPTYPFEHRQ 891 + L++LR R + ++A A+A G D+ AF + R LPTYPF+H + Sbjct: 4489 TTAPARTLSTLRRNEGTLRHLFTSLAQAHAHGLTIDWTPAFTHTEPRTTPLPTYPFQHER 4548 Query: 892 FWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALID--GETVDEQTLRVLN 949 +W DT G T + + EE L D G T D V++ Sbjct: 4549 YWL--------DTAEPPVGQGAGTDTVESGFWDAVEGEEWQTLADTLGVTADAPFDSVMS 4600 Query: 950 KLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXD--WILVGDDTA-AVLEFADAL 1006 L++ +QR + RY I W W++V A E A A+ Sbjct: 4601 ALSSWRLRQREQSLVDGWRYRIEWKPFRAPVSAPDSVSGTWWVVVPAHAGDADRERAQAV 4660 Query: 1007 -----TAGGHRHQIVALPGSDADEAQLVDTLR--AASAGE-LYVVHIAAGDGAAAPMRDL 1058 ++G R +VA+ + D L LR A AG V+ + A D P D+ Sbjct: 4661 RGTLESSGRARTILVAVDPAADDRGSLELKLRDAATEAGPPAGVLSLLATDERPLPGHDV 4720 Query: 1059 LRVQHRTLGGLRR---LFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRA 1114 + GGL L +A DA++ +P+W+ T +D + P Q+ +WG GR Sbjct: 4721 VP------GGLAANLALVQALGDAQIDAPLWVGTCGAVSAGRSDRLANPGQAAVWGLGRV 4774 Query: 1115 AALELPHIWGGLADLSGA-DTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPS 1173 ALE P WGGL DL D + + + EDQ+A+R V RLVR Sbjct: 4775 VALEHPERWGGLIDLPVVLDPRAVERLVTVLAASGEEDQLAVRASGVLVRRLVRVPARQV 4834 Query: 1174 DTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQY 1233 + + + T LVTGG GA+G EVA +LA GA H+VLTSRR Sbjct: 4835 PDGVQWKPEGTVLVTGGTGALGAEVARWLAHGGAEHLVLTSRRGGSAPGAAELTDELLAL 4894 Query: 1234 ACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAG 1293 +V + D+AD VA L+ AE P + +VH AG + L LD ++ V Sbjct: 4895 GTEVTLAACDMADRDAVAALL----AEHAP-SSVVHTAGVLDDGVLDSLDRGRLESVLLP 4949 Query: 1294 KVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVT 1353 KV A HL E D ++ FV SS A V G GQ Y AANA+LD LA + R G+ Sbjct: 4950 KVAAARHLHELTKD--ANVSAFVLFSSAAGVLGSAGQGNYAAANAYLDALAEQRRADGLV 5007 Query: 1354 AVSVNFGPWAAG---MADAESRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDW 1409 A S+ +G W G + D+ RL GV + P A+ + + V+A +DW Sbjct: 5008 AHSIAWGAWDGGGLAVGDSVVEERLRHGGVVPMRPQLAITALQQTLDRAETAVVIADVDW 5067 Query: 1410 SRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXX-LVEQLTKAPVQQRKSLIT 1468 R+L A L E+ L L E+L+ P +++ L+ Sbjct: 5068 PRYLTAVTPRPWLADLPEVAQALNADDAAGAPCGTAGQGSSPLAERLSGRPAPEQRRLVL 5127 Query: 1469 NYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPR 1527 + +R VA V A+ I F +LG DSL AVELR R+ G +P TLV D+P Sbjct: 5128 DLVRTNVAAVLGHAGAESIESGRAFRELGFDSLTAVELRNRLAAATGLRLPTTLVFDYPS 5187 Query: 1528 LSDAADYLLVEVLGL--GEQTNVRQASTVTARTDD-PIAVVAVSCRFPGA-PDPESFWEL 1583 + AD+L + +G G ++ + A DD PIA+V++SCRFPG PE W+L Sbjct: 5188 AAVLADHLYAQAIGSDEGPVADLSSGADPAAGPDDEPIAIVSMSCRFPGGVSSPEELWQL 5247 Query: 1584 LAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAV 1642 L G D I P+DR WD+D YDPDPD PG TY+R FGISPREA+ Sbjct: 5248 LLAGEDTITGFPDDRDWDVDALYDPDPDHPGTTYSRSGAFLSDAAGFDATLFGISPREAL 5307 Query: 1643 WIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFI 1702 ++PQQRL+LET WE ERAG P+ +RGSR GVF G +YA + E I +E + + Sbjct: 5308 AMDPQQRLLLETAWEVFERAGIDPTSVRGSRAGVFVGTNGQDYARHVPQEPIG-VEGYLL 5366 Query: 1703 TGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLL 1762 GNA + ISGR+++ G EGPAV VDTACSS+LVA+H A QAL++G+C +ALAGGV+V+ Sbjct: 5367 AGNAASVISGRLSYTFGLEGPAVTVDTACSSSLVALHLAVQALRNGECSIALAGGVSVMS 5426 Query: 1763 SPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPA 1822 +P V SR R L+ GRCK F +ADG EG GVL+++RLSDA R+G V AV+ Sbjct: 5427 TPAAFVEFSRQRGLAADGRCKAFADAADGTGWGEGVGVLLVERLSDARRNGHPVLAVVRG 5486 Query: 1823 SSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXX 1882 S+VNQDGAS+GLT PNG +QQR+I L A L+G+D+D +EAHGTGT LGDPIE Q Sbjct: 5487 SAVNQDGASNGLTAPNGPSQQRVIRQALVDAALTGSDIDAVEAHGTGTRLGDPIEAQALI 5546 Query: 1883 XXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIP 1942 PL +GSVK+NI HT++A+G AG+IK+V +++HGVLP++LH + P+ H+ Sbjct: 5547 ATYGQDRPANRPLWLGSVKSNIAHTQAAAGVAGVIKMVQAIRHGVLPKTLHVDRPTSHVD 5606 Query: 1943 WDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXX 2002 W+A V ++ E +PW R RRAG+SSFG +GTNAH +VE+AP Sbjct: 5607 WEAGAVELLTEAMPWPETDRPRRAGISSFGVSGTNAHTIVEQAP---------AAEDEPE 5657 Query: 2003 XXXGTDDSPQVL--ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYR 2060 D P V+ LSA + +AL E A R +L P AD+ + R+ ++R Sbjct: 5658 TGPPADAPPTVVPWVLSAATEDALREQAARLATYLDERPEPSPADIGSSLVTTRAALDHR 5717 Query: 2061 AALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQ 2120 A ++ + + VVRG A+LFTGQGSQ GM REL Sbjct: 5718 AVVLGEDRDALRAGLVLLANGKSGPAVVRGLARPGQKVAFLFTGQGSQRLGMGRELHRHL 5777 Query: 2121 PVFAQTVRQCAEAVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQ 2179 PVF Q + A+ LP P+ LFA D A L+ T FAQPALFA+E+ L R + Sbjct: 5778 PVFRQFFDEACAALDAHLPVPIAAALFAQADGADAGLIDGTEFAQPALFALEVALCRTLE 5837 Query: 2180 SWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEH 2239 + P V GHSVG+ AAA VAGVFSL+D ARL+ RG++ +LP GG MVA+ + Sbjct: 5838 FCGVRPVYVAGHSVGEIAAAHVAGVFSLEDAARLVVARGQLMQALPAGGAMVALQVSEDD 5897 Query: 2240 VEQVAG---EFPRVSVGAYNG-PNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSE 2295 + E R+ + A NG +TV+SG E + + E ++ G + L SHAFHS Sbjct: 5898 LLPSLTPWLEQDRLGIAAVNGAASTVVSGDEEAVLAVAEHWQARGRKVRRLTVSHAFHSP 5957 Query: 2296 LLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVR 2355 +DP+LD P +P+V + TG + A YW RH RQ V+F ++++ Sbjct: 5958 RMDPMLDQFRVVVEGIRFAEPAIPVVSSVTGRLAEPGQLTTADYWVRHVRQTVRFHDALQ 6017 Query: 2356 TVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVG 2415 T+ + +EIGP L+ A + A + +LRK ++ + ALA + Sbjct: 6018 TLQTENVTAFLEIGPDGQLSAMAQETL---TAQVHTIPTLRKNRSETTGLLTALAQLHTT 6074 Query: 2416 GHRPDFAA-VHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAA-SG----ILGSGKDL 2469 G PD+ A ++ P +PTYPFQ +W + A D +A SG +LG+ L Sbjct: 6075 GTVPDWTAYLNHHPTPSTPVPTYPFQHHHYWMHGGTQATDVSSAGLSGANHPLLGAAVPL 6134 Query: 2470 ASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYE 2525 A G+ ++T RLSV++ WLADH + TVV+PG + +A+ A VG ++++ Sbjct: 6135 AGGEGHLFTGRLSVRTHRWLADHQVGSTVVLPGTAFVELAVRAGDQVGC-GHVEELTLEA 6193 Query: 2526 PIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGER-----GADWSLNAEGTVDTAGSD 2580 P++LPE + ++QL L AD ++ R +R +W+ +A G V Sbjct: 6194 PLVLPESGAVQIQLRLRRADESGRRELVVYGRLATDREDLWSEEEWTRHASGVV------ 6247 Query: 2581 PDAAADEQSDPVDEVI---ERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAV 2637 AAA +PV + E + +DL+E A +GP + G L++ W D Sbjct: 6248 -VAAAPSAPEPVQLTVWPPEGATELIVKDLYERIAGTSFGYGPAFQG-LRAAWRLDDAVF 6305 Query: 2638 GDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAE 2697 ++++ + +HP L+D E + +P + VTL Sbjct: 6306 AEVVLPQDQYAVASRFGLHPALLDAALHGVALGQPAADTAEPHTDR--MPFSWSGVTL-- 6361 Query: 2698 KMPRRFYCRARWHRSALD-SETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGD 2756 + A R LD + + L D G + + ++ + G+ Sbjct: 6362 -----YAAGATALRVRLDIASPEDVSLLVADGSGAPVAAVNSLKLRPVAADLASAGVADS 6416 Query: 2757 ATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPG--CVPIDRNTDLQVLGEVLS 2814 L+ L W + G W + G A PG V I D+ L + L Sbjct: 6417 ----LFRLEWSKAVDDEPGRAEPGQWALIGTPPGADFTPGEDGVIIGSYPDMAALTDALD 6472 Query: 2815 QAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLW 2874 +G V A P + LL+ + L Sbjct: 6473 ----KGVAVPQRVLLSA-PSEEEQDQAHDLASAVDKATNALLAVLQQWLSDDRFDSSRLA 6527 Query: 2875 IVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXX 2933 ++T H V+ E V D A+ WG R+ +E P L D DG+ Sbjct: 6528 VLTRHAVSTAGQEDVTDLAHASWWGLVRSAQSEHPDRFV-LADTDGTQ-----ISHAALL 6581 Query: 2934 PGI--QEPEIAVRQGKLLASRLLPWARSG 2960 P + EP++A+R G RL SG Sbjct: 6582 PALLSGEPQVALRDGTRYVPRLARAVASG 6610 Score = 813 bits (2100), Expect = 0.0 Identities = 591/1644 (35%), Positives = 826/1644 (50%), Gaps = 64/1644 (3%) Query: 1050 GAAAPMRDLLRVQHRTLGGLRRLFRA--ANDAELRSPIWLVTRDGQRVTDTDTVVP-EQS 1106 G AAP D H T L + +D S + VTR + D + E S Sbjct: 1336 GDAAPA-DTAAATHATTRRAAALIKGWLGDDRFTDSRLVFVTRGAVATSGRDELHDLEHS 1394 Query: 1107 CLWGFGRAAALELPHIWGGLADLSGADT--EWPRLIARITSPRDGEDQIALRGDAVYAPR 1164 +WG R+A E P + L DL DT E P I + Q+ LR + R Sbjct: 1395 TVWGLVRSAQTENPGRFA-LLDLDDPDTVTELPEAILA------DQAQLVLRDGRLGNLR 1447 Query: 1165 LVRRTGEPSDTPLPV-REDRTYLVTGGLGAIGLEVAGYL-ASHGAGHVVLTSRREPXXXX 1222 L + G P P D T L+TGG G +G VA +L A HG ++L SRR P Sbjct: 1448 LAK--GAAIQDPDPGWGVDGTVLITGGTGVLGGLVARHLVAGHGVRRLLLCSRRGPDAPG 1505 Query: 1223 XXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGL 1282 DV V D AD +A L+ TV A PL G+VH AG I ++ L Sbjct: 1506 AVELVAELTALGADVTVAACDAADRDALAALLDTVPAT-HPLTGVVHTAGVIDDATVTTL 1564 Query: 1283 DDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDG 1342 +D V KV A +L + L L FV SS A ++GG GQ Y AANAFLD Sbjct: 1565 TPERIDAVLRPKVDAALNLHQLTAHL--GLTRFVLFSSAAGLFGGAGQGNYAAANAFLDA 1622 Query: 1343 LAWRLRERGVTAVSVNFGPWA--AGMA---DAESRARLEQRGVRTLSPAEALAGMADVVA 1397 LA + +G+ VS+ +G W GM DA R+ + GV LS + L + D+ Sbjct: 1623 LAQLRKRQGLPGVSLAWGAWVQDGGMTATLDAGDVERMARGGVLPLSHEQGL-NLFDLAV 1681 Query: 1398 GPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTK 1457 + +VA + A L L E L ++L+ Sbjct: 1682 AGSEPLVAPMRLDTTALRESGATVPEMLRGLVRE--RSRRRVGPSHTTSAAMALEQRLSG 1739 Query: 1458 APVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKD 1516 +R++ + + + VA V D I + F D G DSL AVELR + G Sbjct: 1740 LVEGERRAALLDLVCGHVARVLGHADPSSIEETRPFKDTGFDSLTAVELRNVLHGATGLR 1799 Query: 1517 IPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP- 1575 +P TLV D+P + D+L E+LG E + A A D+PIA+VA+SCR+PG Sbjct: 1800 LPATLVFDYPTPAALTDHLYDELLGSREDAVL--APITRAAYDEPIAIVAMSCRYPGGVC 1857 Query: 1576 DPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFF 1634 PE W L+A G D I + P+DR WDID YDPDP PG +YTR P FF Sbjct: 1858 TPEDLWRLVAEGRDTITDFPDDRGWDIDALYDPDPGHPGTSYTRRGGFLSDAAGFDPAFF 1917 Query: 1635 GISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESI 1694 ISPREA+ ++PQQRL+LE WE ERA P+ L+GS+ GVF G A Y + ES Sbjct: 1918 RISPREALAMDPQQRLLLEMTWEMFERALIDPTTLKGSQAGVFIGTAGPGYGGRIHHES- 1976 Query: 1695 DKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLAL 1754 +E + G + SGR+++ G EGPA+ VDT CSS+LVA+H A Q+L++G+ +AL Sbjct: 1977 QGVEGQQLFGGSAAVTSGRISYTFGLEGPAMTVDTMCSSSLVALHLAVQSLRNGESSMAL 2036 Query: 1755 AGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGD 1814 AGGV V+ P SR R LSP GRCK+F +ADG EG GVL+L+RLSDA R+G Sbjct: 2037 AGGVTVMSRPAAFTEFSRQRGLSPDGRCKSFADAADGTGWGEGAGVLLLERLSDARRNGH 2096 Query: 1815 RVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGD 1874 V AVI S+VNQDGAS+GLT PNG +QQR+I LA A LS ADVD +EAHGTGTPLGD Sbjct: 2097 PVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANASLSPADVDAVEAHGTGTPLGD 2156 Query: 1875 PIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHF 1934 PIE Q PL +GSVK+NI H ++A+ G+IK+V +++HG+LP++LH Sbjct: 2157 PIEAQALIATYGQDRPADRPLRLGSVKSNIAHAQAAAAVGGVIKMVQAIRHGLLPKTLHV 2216 Query: 1935 ENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAP-PQLHXXX 1993 E PS H+ W A V ++ E +PW + RRAGVS+FG +GTNAH+++E+AP P Sbjct: 2217 EQPSRHVDWSAGSVELLTEAMPWPETDQPRRAGVSAFGGSGTNAHMIIEQAPAPDEEHTD 2276 Query: 1994 XXXXXXXXXXXXGTDDSPQV-LALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGV 2052 P V LSA++ +AL ARR L A P L ADV H+ Sbjct: 2277 GTSRTSGESGAEQARPLPMVPWLLSAKTSQALAAQARRLSAHLRANPDLRSADVAHSLLT 2336 Query: 2053 GRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGM 2112 RS RA + +V+G T ++F GQGSQ+ GM Sbjct: 2337 TRSVHAERAVFIAGDRDEALAALDALADGTPAPHLVQGLADVSGKTVFVFPGQGSQWVGM 2396 Query: 2113 ARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEM 2172 A EL D VFA+ + CA A+ + L DVL TD L+ QP L+AV + Sbjct: 2397 AVELLDGSEVFAEHMAACARALEPFVDWSLEDVLRQTDGTWP--LERVEVVQPVLWAVMV 2454 Query: 2173 GLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEG-GRMV 2231 LA LWQ+ +EP VLGHS G+ AAACVAG SL+DGAR++A R + G G M+ Sbjct: 2455 SLAGLWQAHGVEPAAVLGHSQGEIAAACVAGALSLEDGARVVALRSQAIAETLAGHGGML 2514 Query: 2232 AVFADAEHVEQVAGEF-PRVSVGAYNGPNT-VLSGPGEDLEEIVERFEDEGIRCTWLATS 2289 ++ A A + + + R+S+ NGP++ V++G + LE + E G+R + Sbjct: 2515 SIAAPATDIAPLIARWNERISIATVNGPHSVVVAGDPDALEALRGELETRGLRNRRIPVD 2574 Query: 2290 HAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQ 2349 +A H+ ++ + + ++P++ TGA L T +DA+YW R+ RQ V+ Sbjct: 2575 YASHTPHVEAIRERLLADLAVIQPRAASIPVLSTVTGAWL-DTTVMDAEYWYRNLRQTVE 2633 Query: 2350 FAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADAL 2409 F + RT+ +EI P PVL+ A V+ + +LR+ D AL Sbjct: 2634 FEAATRTLLDQDHRYFVEISPHPVLS-AMVRDCLDTSRPVVTAPTLRRDRTDATAALTAL 2692 Query: 2410 ASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSIAVDGGTAASG-----IL 2463 A A+ G D+A++ R V LPTYPFQR+ +W + + + D TA +L Sbjct: 2693 AEAHGHGVPVDWASLFAGSTARAVHLPTYPFQRQHYWLDSGTGSSDMSTAGLASPDHPLL 2752 Query: 2464 GSGKDLASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPA---RLK 2519 G+ +A D ++T RLSV++ PWLADH I G+V++PG + +A+ A G A R++ Sbjct: 2753 GAVTTVAGEDGHLFTGRLSVRTHPWLADHQITGSVLLPGTAFVELAVRA-GDQAGCGRVE 2811 Query: 2520 DVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGAD-WSLNAEGTVDTAG 2578 ++ P++LPE+ S VQ+ + D + +++S G + W LNA G + AG Sbjct: 2812 ELTLLAPLVLPEEGSVRVQMKVGEPDATGRRTIEVYSSDQQAPGRERWVLNASGML--AG 2869 Query: 2579 SDPDAAADEQSDPVDEVIERLERMRPQDLF-ETFADLELAWGPTWSGSLKSLWLGDGEAV 2637 +A + P + + P D F + A +GPT+ G L + W E Sbjct: 2870 EPVEAPPSLTTWPPEGAVP-----VPLDGFHDRLAARGFGYGPTFRG-LSAAWSRGDEIF 2923 Query: 2638 GDILVGAELAEQLGSEPMHPVLMD 2661 + + + + +HP L+D Sbjct: 2924 AEAALPSGHRQDAARFGLHPALLD 2947 Score = 791 bits (2044), Expect = 0.0 Identities = 542/1453 (37%), Positives = 740/1453 (50%), Gaps = 80/1453 (5%) Query: 1082 RSPIWLVTRDGQRV-TDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI 1140 RS + ++TR V TD + + G R+A E P + L D+ + W L Sbjct: 3145 RSRLIVLTRGAVAVGTDEGVTDLVSASVRGLVRSAQAEHPGRFS-LVDIDDREESWAVLS 3203 Query: 1141 ARITSPRDGEDQIALRGDAVYAPRL----VRRTGEPSDTPLPVREDRTYLVTGGLGAIGL 1196 A S GE Q+ALR + PRL V TG P + P D T L+TGG G +G Sbjct: 3204 AAAVS---GEPQVALRCGQMKVPRLGSVDVPTTGMP-EMPDVWGVDGTVLITGGTGVLGG 3259 Query: 1197 EVAGYL-ASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMT 1255 VA +L A HG ++L SRR P DV V D AD +A L+ Sbjct: 3260 LVARHLVAGHGVRRLLLCSRRGPDAPGAVELVAELTALGADVTVAACDAADRDALAALLD 3319 Query: 1256 TVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFF 1315 TV A PL G+VH AG I ++ L +D V KV A +L + L L F Sbjct: 3320 TVPAT-HPLTGVVHTAGVIDDATVTTLTPERIDAVLRPKVDAALNLHQLTAHL--GLTRF 3376 Query: 1316 VSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-----AGMADAE 1370 V SS A ++GG GQ Y AANAFLD LA R G+ A S+ +G WA G DA Sbjct: 3377 VLFSSAAGLFGGAGQGNYAAANAFLDALAQHRRANGLNAQSLAWGLWAEASGMTGHLDAA 3436 Query: 1371 SRARLEQRGVRTLSPAEALAGMADVVAGPVQG--VVAKIDWSRFLPLYQQAGRRAFLSEL 1428 AR+ + G+ + + LA + D + V A +D +R L G L Sbjct: 3437 DLARMGRSGLTAMPTGDGLA-LLDTAQRVDEATLVTAALD-TRALHARAADGTLPALFHA 3494 Query: 1429 ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIR 1487 + L ++L+ V +R++ + + + VA V D I Sbjct: 3495 LVPVPRRSATSPAAQAAGPDG-LRQRLSGLVVGERRAALLDLVCGHVARVLGHADPSSIE 3553 Query: 1488 DEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLG------ 1541 + GF D G DSL AVE R R+ G +P TLV D+P + D+L E+LG Sbjct: 3554 ENKGFKDTGFDSLSAVEFRNRLHGATGLRLPATLVFDYPTPAALTDHLYDELLGSREDAV 3613 Query: 1542 ------------------------------LGEQTNVRQASTVTARTDDPIAVVAVSCRF 1571 LG + + A A D+PIA+V ++CR+ Sbjct: 3614 LAPITRAAYDPVDFDYPTPAALTDHLYDELLGSREDAVLAPITRAAYDEPIAIVGMACRY 3673 Query: 1572 PGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXX 1629 PG + PE W+L+A G DAI + P DR W+++ Y PDPD PG +YTR Sbjct: 3674 PGGVESPEDLWQLVADGRDAISDFPADRGWNVESLYHPDPDHPGTSYTRAGGFLHDAADF 3733 Query: 1630 XPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLL 1689 PEFFGISPREA+ +PQQRL+LET WE +ERAG PS L+G+ TGVF GV N+Y + Sbjct: 3734 DPEFFGISPREALATDPQQRLLLETSWEAMERAGINPSTLKGTPTGVFLGVMYNDYGTAM 3793 Query: 1690 SAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGD 1749 ++ + E H +G+A + SGRV++ G EGPAV VDTACSS+LVA+H A QAL++G+ Sbjct: 3794 Q-QAAEVFEGHMASGSAGSVASGRVSYTFGLEGPAVTVDTACSSSLVALHLAAQALRNGE 3852 Query: 1750 CDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDA 1809 C LALAGGV V+ +P T V SR R L+ GRCK F +ADG EG GVL+++RLSDA Sbjct: 3853 CTLALAGGVAVMSTPATFVEFSRQRGLAADGRCKAFADAADGTGWGEGVGVLLVERLSDA 3912 Query: 1810 VRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTG 1869 R+G V AV+ S+VNQDGAS+GLT PNG +QQR+I+ LA AGL+GADVD +EAHGTG Sbjct: 3913 RRNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIQQALANAGLAGADVDAVEAHGTG 3972 Query: 1870 TPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLP 1929 T LGDPIE Q PL +GS+K+NIGHT++A+G AG+IK+V ++QHG LP Sbjct: 3973 TRLGDPIEAQALIATYGQARSADRPLWLGSLKSNIGHTQAAAGVAGVIKMVQAMQHGTLP 4032 Query: 1930 QSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQL 1989 +LH + P+ + W V ++ E VPW + R RR VSSFG +GTNAHV++E P Sbjct: 4033 PTLHIDQPTGQVDWATGAVELLTEAVPWPDSDRPRRVAVSSFGVSGTNAHVIIEHTP--- 4089 Query: 1990 HXXXXXXXXXXXXXXXGTDD----SPQVLALSARSPEALVELARRYDDWLSATPGLDIAD 2045 H G D S LSA++ +AL ARR L A P L AD Sbjct: 4090 HTPHTTRTCPILPIPPGPADCAGPSAGAWLLSAKTSQALAAQARRLSAHLRANPDLRSAD 4149 Query: 2046 VCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQ 2105 V H+ RS RA + +V+G T ++F GQ Sbjct: 4150 VAHSLLTTRSVHAERAVFIAGDRDEALAALDALADGTPAPHLVQGLADVSGKTVFVFPGQ 4209 Query: 2106 GSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQP 2165 GSQ+ GMA EL D VFA+ + CA A+ + L DVL TD L+ QP Sbjct: 4210 GSQWVGMAVELLDGSEVFAEHMAACARALEPFVDWSLEDVLRQTDGTWP--LERVEVVQP 4267 Query: 2166 ALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLP 2225 L+AV + LA LWQ+ +EP VLGHS G+ AAACVAG SL+DGAR++A R + Sbjct: 4268 VLWAVMVSLAGLWQAHGVEPAAVLGHSQGEIAAACVAGALSLEDGARVVALRSQAIAETL 4327 Query: 2226 EG-GRMVAVFADAEHVEQVAGEF-PRVSVGAYNGPNT-VLSGPGEDLEEIVERFEDEGIR 2282 G G M+++ A A + + + R+S+ NGP++ V++G + LE + E G+R Sbjct: 4328 AGHGGMLSIAAPATDIAPLIARWNERISIATVNGPHSVVVAGDPDALEALRGELETRGLR 4387 Query: 2283 CTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRR 2342 + +A H+ ++ + + ++P++ TGA L T +DA+YW R Sbjct: 4388 NRRIPVDYASHTPHVEAIRERLLADLAVIQPRAASIPVLSTVTGAWL-DTTVMDAEYWYR 4446 Query: 2343 HSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADR 2402 + RQ V+F + RT+ +EI P PVLT Q E A R +++LR+ Sbjct: 4447 NLRQTVEFEAATRTLLDQDHRYFVEISPHPVLTIGLQQTIEETTAPARTLSTLRRNEGTL 4506 Query: 2403 RQIADALASAYVGGHRPDF--AAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAAS 2460 R + +LA A+ G D+ A H +P R LPTYPFQ R+W + V G Sbjct: 4507 RHLFTSLAQAHAHGLTIDWTPAFTHTEP-RTTPLPTYPFQHERYWLDTAEPPVGQGAGTD 4565 Query: 2461 GILGSGKDLASGD 2473 + D G+ Sbjct: 4566 TVESGFWDAVEGE 4578 Score = 725 bits (1872), Expect = 0.0 Identities = 455/1166 (39%), Positives = 624/1166 (53%), Gaps = 60/1166 (5%) Query: 1545 QTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDR-WDID 1602 Q + R+ + + A +PIA+V +CR+PG PE W L+A G AI P DR WD++ Sbjct: 23 QQSRRRVAELEAAEAEPIAIVGTACRYPGGVRSPEDLWRLVAEGQHAISSFPTDRGWDLE 82 Query: 1603 EFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERA 1662 + YDPDPD PGK+Y R FFGISPREA+ ++PQQRL+LET WE ERA Sbjct: 83 DLYDPDPDRPGKSYARDGGFLDGAAQFDAAFFGISPREALAMDPQQRLLLETTWEVFERA 142 Query: 1663 GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEG 1722 G P+ LRGSRTGVF G++ +YA S + E H +TG A++ +SGRVA+A G EG Sbjct: 143 GIDPTSLRGSRTGVFAGISHQDYA-AGQRPSAEVSEGHLMTGTAVSVVSGRVAYAFGLEG 201 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PA+ VDTACSS+LVA+H A QAL++G+C LA+AGGV V+ +P SR R L+P GRC Sbjct: 202 PAMTVDTACSSSLVALHLAAQALRNGECTLAVAGGVTVMATPGAFTRFSRERGLAPDGRC 261 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 K F + ADG SEG GVL+++RLSDA R+G V AV+ S+VNQDGAS+GLT PNG +Q Sbjct: 262 KAFSSDADGTGFSEGVGVLLVERLSDARRNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQ 321 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QR+I+ LA AGL+GADVD +EAHGTGT LGDPIE Q PL +GS+K+ Sbjct: 322 QRVIQQALANAGLAGADVDAVEAHGTGTRLGDPIEAQALIATYGQARSADRPLWLGSLKS 381 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGHT++A+G AG+IK++ ++ HG LP++LH PSP + W A V ++ E +PW R Sbjct: 382 NIGHTQAAAGVAGVIKMIQAMGHGTLPRTLHVNQPSPQVDWAAGAVELLTEAMPWPEGDR 441 Query: 1963 VRRAGVSSFGFTGTNAHVLVEE-APPQLHXXXXXXXXXXXXXXXG----------TDDSP 2011 RRAG+SSFG +GTNAHV++E+ APP+ G T+ P Sbjct: 442 PRRAGISSFGISGTNAHVIIEQGAPPRTASDPGESRADEPGVRGGAPVPATTESATEPQP 501 Query: 2012 QVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXX 2071 LS S AL A R + + G+ AD+ + R+ E+RA +V Sbjct: 502 VPWLLSGHSATALRAQADRLKSYAANNTGIRPADIGFSLVTTRAALEHRAVVVAADHAGF 561 Query: 2072 XXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCA 2131 T GVV G V +A+LF+GQGSQ GM REL PVFA+ Sbjct: 562 TAGLDALAEGRTAPGVVSGTVVAGARSAFLFSGQGSQRVGMGRELQQAFPVFAEAFEAVC 621 Query: 2132 EAVADMLPRPLLD-VLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLG 2190 V L PLLD VL A D + LL T++ QPALFA+E+ L RL +SW + PD V G Sbjct: 622 AQVDPYLEHPLLDVVLAAPDSDFGALLHQTAYTQPALFALEVALFRLVESWGVRPDYVAG 681 Query: 2191 HSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAG---EF 2247 HSVG+ AAA VAGVFSL+D ARL+ RG++ +LP G MVA+ + V E Sbjct: 682 HSVGEIAAAHVAGVFSLEDAARLVVARGQLMQALPAEGAMVALQVSEDEVLPSLTPWLEQ 741 Query: 2248 PRVSVGAYNG-PNTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXX 2306 RV V A NG +TV+SG E + + E ++ G + L SHAFHS +DP+LD Sbjct: 742 DRVDVAAVNGAASTVVSGDEEAVLAVAEHWQARGRKVRRLTVSHAFHSPRMDPMLDQFRV 801 Query: 2307 XXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM 2366 P +P+V + TG + A YW RH RQ V+F ++++T+ + + Sbjct: 802 VVEGIRFAEPAIPVVSSVTGRLAEPGQLTTADYWVRHVRQTVRFHDALQTLQTENVTAFL 861 Query: 2367 EIGPQPVL----------TGAAVQVWP----EHMAAPRAVASL----RKGVA-DRRQIAD 2407 EIGP L TGA V P E AP A+ ++ GV+ D R Sbjct: 862 EIGPDGQLSAMTRDFLTDTGAHAAVAPLLRRERPEAPSALTAIAGLHTHGVSIDWRTYFT 921 Query: 2408 ALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAASGILGSGK 2467 + +++ PV+LPTY FQ + FW A G + +G+ Sbjct: 922 STSTSTSTSTGTGTGTGQATADTPVQLPTYAFQHQSFW--LGPTAPVGDVSTAGLTSPDH 979 Query: 2468 DLAS--------GDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTP--AR 2517 L S G + T RLS +S W+ DH I G V++PG + + A +R Sbjct: 980 PLLSAATTTAVDGSLLLTGRLSQRSPAWIGDHRIGGVVLLPGTALVELVVRAGDQAGCSR 1039 Query: 2518 LKDVFFYEPIILPEKASREVQLTL-HPADGGSVLSFQIHSRPYGERGAD-WSLNAEGTVD 2575 + ++ P+ LPE + +Q+ + PA G IHS G + W+LNA G + Sbjct: 1040 IDELIMLTPLTLPEHGAVRIQVAVGGPAHDGR-RPVHIHSSTSDTTGDEQWTLNASGLLT 1098 Query: 2576 TAGSDPDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGE 2635 +DP A D + R+ L+E A+ +GP + G L++ W + Sbjct: 1099 VEMTDPPA------DLTPWPPQHATRIPLDGLYERLAESGYGYGPVFQG-LRAAWTLGDD 1151 Query: 2636 AVGDILVGAELAEQLGSEPMHPVLMD 2661 ++ + A +HP L+D Sbjct: 1152 TYAEVEIPAGDQTDTDRYELHPALLD 1177 Score = 653 bits (1685), Expect = 0.0 Identities = 394/943 (41%), Positives = 511/943 (54%), Gaps = 53/943 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G A R+PG S E+ W L+ +G+ AIS P DR WD+E+ +DPDP PGK R Sbjct: 41 AIVGTACRYPGGVRSPEDLWRLVAEGQHAISSFPTDRGWDLEDLYDPDPDRPGKSYARDG 100 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+D FDA FFG+S RE MDPQ R+L+ET W E +GI PTSL S TGVF G+ Sbjct: 101 GFLDGAAQFDAAFFGISPREALAMDPQQRLLLETTWEVFERAGIDPTSLRGSRTGVFAGI 160 Query: 133 ATHDYLGMASDELTYPEI-EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 + DY A+ + E+ E ++ GT+ + +GR++Y GL+GPA+ VDTACSSSLVA+ Sbjct: 161 SHQDY---AAGQRPSAEVSEGHLMTGTAVSVVSGRVAYAFGLEGPAMTVDTACSSSLVAL 217 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR EC LA+AGG V+ TP FS LAPDGRCK F + ADG EG Sbjct: 218 HLAAQALRNGECTLAVAGGVTVMATPGAFTRFSRERGLAPDGRCKAFSSDADGTGFSEGV 277 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 GV++V+RL DA R+G + AV+ GSA+NQDGAS GLT PNG +QQRVI AL AGL A Sbjct: 278 GVLLVERLSDARRNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIQQALANAGLAGA 337 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT LGDPIEAQA G R+ + PL +GS K+NIGH + Sbjct: 338 DVDAVEAHGTGTRLGDPIEAQALIATYGQARSADRPLWLGSLKSNIGHTQAAAGVAGVIK 397 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 + + TLP+ L+ PSP + W +E++ E +PW +PR AG+SSFG +GTNA Sbjct: 398 MIQAMGHGTLPRTLHVNQPSPQVDWAAGAVELLTEAMPWPEGDRPRRAGISSFGISGTNA 457 Query: 432 HVILEEAPAVGT--------------------PATTEPVEDPRRYSVLPLSARTPEALVR 471 HVI+E+ T PATTE +P+ L LS + AL Sbjct: 458 HVIIEQGAPPRTASDPGESRADEPGVRGGAPVPATTESATEPQPVPWL-LSGHSATALRA 516 Query: 472 LAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPG 531 A + + + R AD+ + T RA LE RA +V L ALA+ R APG Sbjct: 517 QADRLKSYAANNTGIRPADIGFSLVTTRAALEHRAVVVAADHAGFTAGLDALAEGRTAPG 576 Query: 532 LVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVI 591 +V G ++A+LF+GQGSQ GM REL PVFAE V LE PLLDV+ Sbjct: 577 VVSGTVVAGARSAFLFSGQGSQRVGMGRELQQAFPVFAEAFEAVCAQVDPYLEHPLLDVV 636 Query: 592 FDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAG 651 A D D + L T Y QPALFA+E+ L RL +SWG PD V GHSVG+ +AA VAG Sbjct: 637 LAAP--DSDFGALLHQTAYTQPALFALEVALFRLVESWGVRPDYVAGHSVGEIAAAHVAG 694 Query: 652 VFDVEDGARLIAERGRLFGSLPAGGRMAAV-FTAPERAERLTD--EYPSLSVAAYNG-AN 707 VF +ED ARL+ RG+L +LPA G M A+ + E LT E + VAA NG A+ Sbjct: 695 VFSLEDAARLVVARGQLMQALPAEGAMVALQVSEDEVLPSLTPWLEQDRVDVAAVNGAAS 754 Query: 708 TVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRI 767 TV+SG + + + A G + L SHAFHS +DP+LD F + + + EP Sbjct: 755 TVVSGDEEAVLAVAEHWQARGRKVRRLTVSHAFHSPRMDPMLDQFRVVVEGIRFAEPAIP 814 Query: 768 LIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATAL 827 ++ + TG YW RH RQ V F +++TL N LEIGP L+A Sbjct: 815 VVSSVTGRLAEPGQLTTADYWVRHVRQTVRFHDALQTLQTENVTAFLEIGPDGQLSAMTR 874 Query: 828 AAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARK-------- 879 D V LR + A+A + G D+R + + Sbjct: 875 DFLTDTGAHAAVAPLLRRERPEAPSALTAIAGLHTHGVSIDWRTYFTSTSTSTSTSTGTG 934 Query: 880 -----------LDLPTYPFEHRQFWFSDNRAIDRDTQTASAGS 911 + LPTY F+H+ FW + D TA S Sbjct: 935 TGTGQATADTPVQLPTYAFQHQSFWLGPTAPVG-DVSTAGLTS 976 Score = 624 bits (1610), Expect = e-176 Identities = 383/932 (41%), Positives = 516/932 (55%), Gaps = 28/932 (3%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + R+PG + E+ W L+ +GR+ I+D P DR WDI+ +DPDP PG TRR Sbjct: 1844 AIVAMSCRYPGGVCTPEDLWRLVAEGRDTITDFPDDRGWDIDALYDPDPGHPGTSYTRRG 1903 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D GFD FF +S RE MDPQ R+L+E W E + I PT+L S GVF+G Sbjct: 1904 GFLSDAAGFDPAFFRISPREALAMDPQQRLLLEMTWEMFERALIDPTTLKGSQAGVFIGT 1963 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 A Y G E +E G S A +GRISY GL+GPA+ VDT CSSSLVA+H Sbjct: 1964 AGPGYGGRIHHESQ--GVEGQQLFGGSAAVTSGRISYTFGLEGPAMTVDTMCSSSLVALH 2021 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A Q+LR E +ALAGG V+ PA FS L+PDGRCK+F AADG GEG G Sbjct: 2022 LAVQSLRNGESSMALAGGVTVMSRPAAFTEFSRQRGLSPDGRCKSFADAADGTGWGEGAG 2081 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V++++RL DA R+G + AVIRGSA+NQDGAS GLT PNG +QQRVI AL A L PAD Sbjct: 2082 VLLLERLSDARRNGHPVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANASLSPAD 2141 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R + PL +GS K+NI H + Sbjct: 2142 VDAVEAHGTGTPLGDPIEAQALIATYGQDRPADRPLRLGSVKSNIAHAQAAAAVGGVIKM 2201 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LPK L+ E PS H+ W +E++ E +PW +PR AGVS+FG +GTNAH Sbjct: 2202 VQAIRHGLLPKTLHVEQPSRHVDWSAGSVELLTEAMPWPETDQPRRAGVSAFGGSGTNAH 2261 Query: 433 VILEEAPAV------GTPATT--EPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRA 482 +I+E+APA GT T+ E R ++P LSA+T +AL A LRA Sbjct: 2262 MIIEQAPAPDEEHTDGTSRTSGESGAEQARPLPMVPWLLSAKTSQALAAQARRLSAHLRA 2321 Query: 483 HPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPK 542 +P R ADV+H+ T R+ +RA + R+ A+ L ALAD PAP LV+G + + K Sbjct: 2322 NPDLRSADVAHSLLTTRSVHAERAVFIAGDRDEALAALDALADGTPAPHLVQGLADVSGK 2381 Query: 543 TAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTE 602 T ++F GQGSQ+ GMA EL D VFAE + CA A+ ++ L DV+ D Sbjct: 2382 TVFVFPGQGSQWVGMAVELLDGSEVFAEHMAACARALEPFVDWSLEDVLRQT-----DGT 2436 Query: 603 SPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLI 662 PL QP L+AV + LA LWQ+ G EP V+GHS G+ +AACVAG +EDGAR++ Sbjct: 2437 WPLERVEVVQPVLWAVMVSLAGLWQAHGVEPAAVLGHSQGEIAAACVAGALSLEDGARVV 2496 Query: 663 AERGRLFGSLPA--GGRMAAVFTAPERAERLTDEYPSLSVAAYNGANT-VLSGPAKDLES 719 A R + A GG ++ A + A + +S+A NG ++ V++G LE+ Sbjct: 2497 ALRSQAIAETLAGHGGMLSIAAPATDIAPLIARWNERISIATVNGPHSVVVAGDPDALEA 2556 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 L G+R + +A H+ ++ I + + ++ R ++ TG+ L Sbjct: 2557 LRGELETRGLRNRRIPVDYASHTPHVEAIRERLLADLAVIQPRAASIPVLSTVTGAWLD- 2615 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 +T +D YW R+ RQ VEF + RTL D + R +EI P PVL+A D + Sbjct: 2616 TTVMDAEYWYRNLRQTVEFEAATRTLLDQDHRYFVEISPHPVLSAMVRDCL-DTSRPVVT 2674 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDARKLDLPTYPFEHRQFWFSDNR 898 +LR D A+A A+ G D+ + F AR + LPTYPF+ + +W D+ Sbjct: 2675 APTLRRDRTDATAALTALAEAHGHGVPVDWASLFAGSTARAVHLPTYPFQRQHYWL-DSG 2733 Query: 899 AIDRDTQTASAGSVTPHRTQAVRLL--EDGQI 928 D TA S AV + EDG + Sbjct: 2734 TGSSDMSTAGLASPDHPLLGAVTTVAGEDGHL 2765 Score = 150 bits (379), Expect = 4e-33 Identities = 116/360 (32%), Positives = 162/360 (45%), Gaps = 23/360 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G A +LA GA +VLTSRR + + + A D+ Sbjct: 4847 LVTGGTGALGAEVARWLAHGGAEHLVLTSRRGGSAPGAAELTDELLALGTEVTLAACDMA 4906 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D VA LLA E P + + H AGVLDD +L + + R + L PK A H Sbjct: 4907 DRDAVAALLA----EHAP-SSVVHTAGVLDDGVLDSLDRGRLESVLLPKVAAARHLHELT 4961 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQ NYA ANA LD L +RRA GLVA I +G W GG+ Sbjct: 4962 KDANVSAFVLFSSAAGVLGSAGQGNYAAANAYLDALAEQRRADGLVAHSIAWGAWDGGGL 5021 Query: 3478 ASSEAAT-ANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPI 3536 A ++ + G++P+ P A+ AL + + + +W R + + RP + Sbjct: 5022 AVGDSVVEERLRHGGVVPMRPQLAITALQQTLDRAETAVVIADVDWPRYLTAV-TPRPWL 5080 Query: 3537 LDLV-------LPSAAG-----EATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 DL AAG G S L ++L P P++ V + ++ V L Sbjct: 5081 ADLPEVAQALNADDAAGAPCGTAGQGSSPLAERLSGRPAPEQRRLVLDLVRTNVAAVLGH 5140 Query: 3585 ASPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 A + S F +LG DSL A+ELRNRL + G + T VFDYP+ LA++L Q Sbjct: 5141 AGAESIESGRAFRELGFDSLTAVELRNRLAAATG--LRLPTTLVFDYPSAAVLADHLYAQ 5198 Score = 150 bits (379), Expect = 4e-33 Identities = 163/588 (27%), Positives = 228/588 (38%), Gaps = 36/588 (6%) Query: 966 DARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADE 1025 D+ + + W W L+G A T G + + GS D Sbjct: 6415 DSLFRLEWSKAVDDEPGRAEPGQWALIGTPPGA------DFTPG----EDGVIIGSYPDM 6464 Query: 1026 AQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRA--ANDAELRS 1083 A L D L A V+ A + DL + L + + ++D S Sbjct: 6465 AALTDALDKGVAVPQRVLLSAPSEEEQDQAHDLASAVDKATNALLAVLQQWLSDDRFDSS 6524 Query: 1084 PIWLVTRDGQRVTDTDTVVP-EQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIAR 1142 + ++TR + V + WG R+A E P + LAD G L+ Sbjct: 6525 RLAVLTRHAVSTAGQEDVTDLAHASWWGLVRSAQSEHPDRFV-LADTDGTQISHAALLPA 6583 Query: 1143 ITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYL 1202 + S GE Q+ALR Y PRL R V T LVTGG G +G +A +L Sbjct: 6584 LLS---GEPQVALRDGTRYVPRLARAVASGDGPVARVDPAGTVLVTGGTGTLGSSLARHL 6640 Query: 1203 A-SHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAEL 1261 HG ++L SRR DV V DV D VA L+ + A Sbjct: 6641 VVEHGVRRLLLVSRRGGESEGAAELVAELTGLGADVTVAACDVGDRGAVAELLAGIPAG- 6699 Query: 1262 PPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSI 1321 PL +VHA+G + L +V RV KV GA +L E L DL FV SS Sbjct: 6700 HPLTAVVHASGVTDDAVIEALTAEQVGRVLRSKVDGAVNLHELTRGL--DLSAFVLFSSA 6757 Query: 1322 ASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW--AAGMADAESRARLEQRG 1379 A V+G GQ Y AANAFLD LA R R G+ A S+ +G W A+ M + A L + G Sbjct: 6758 AGVFGNPGQGNYAAANAFLDALAVRRRAEGLAARSLAWGLWEEASAMTSRLAGADLVRMG 6817 Query: 1380 VRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPL-YQQAGRRAFLSELESEL-----X 1433 L P G+A + + D LP+ R+ + + L Sbjct: 6818 RAGLLPLTTGQGLA------LFDAAHRTDEPLVLPMRLDTTALRSTTGQPPALLRNLVRV 6871 Query: 1434 XXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRD-EAGF 1492 +QL V +R ++ +R A V E D + GF Sbjct: 6872 QARRTAGAAPGPDAAATFQQQLISLSVAERGRVLLETVRGHAAAVLGHSGPEAVDVDKGF 6931 Query: 1493 FDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVL 1540 + G DSL AVE R R+ G +P T+ D+P + A++LL ++ Sbjct: 6932 MEAGFDSLSAVEFRNRLTSTTGLRMPATVTFDYPSPAALAEHLLTRLV 6979 Score = 138 bits (348), Expect = 1e-29 Identities = 120/368 (32%), Positives = 172/368 (46%), Gaps = 22/368 (5%) Query: 3298 LITGGLGAIGLHTAAYLA-QLGAGDIVLTSRRDPD-ESAQRAIDEITERHKCRIHTYAAD 3355 L+TGG G +G A +L + G ++L SRR + E A + E+T + A D Sbjct: 6624 LVTGGTGTLGSSLARHLVVEHGVRRLLLVSRRGGESEGAAELVAELTGLG-ADVTVAACD 6682 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 VGD VA+LLA I A PL + H +GV DDA++ A E+ L K GA + Sbjct: 6683 VGDRGAVAELLAGIPAG-HPLTAVVHASGVTDDAVIEALTAEQVGRVLRSKVDGAVNLHE 6741 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 PGQ NYA ANA LD L +RRA+GL A + +G W + Sbjct: 6742 LTRGLDLSAFVLFSSAAGVFGNPGQGNYAAANAFLDALAVRRRAEGLAARSLAWGLWEEA 6801 Query: 3476 GMASSEAATANITAQ---GLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA 3532 +S A A++ GL+PL L AL + A+ + + VL A + Sbjct: 6802 SAMTSRLAGADLVRMGRAGLLPLTTGQGL-ALFDA-AHRTDEPLVLPMRLDTTALRSTTG 6859 Query: 3533 RPPIL--DLVLPSA---AGEATGD---SELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 +PP L +LV A AG A G + +QL+ + + +R + E ++ L Sbjct: 6860 QPPALLRNLVRVQARRTAGAAPGPDAAATFQQQLISLSVAERGRVLLETVRGHAAAVLGH 6919 Query: 3585 ASPPA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 + P A F++ G DSL A+E RNRL S G + AT FDYP+ LAE+L+ + Sbjct: 6920 SGPEAVDVDKGFMEAGFDSLSAVEFRNRLTSTTG--LRMPATVTFDYPSPAALAEHLLTR 6977 Query: 3643 L-PDAEAP 3649 L P+ P Sbjct: 6978 LVPEVAMP 6985 Score = 131 bits (329), Expect = 2e-27 Identities = 112/365 (30%), Positives = 156/365 (42%), Gaps = 19/365 (5%) Query: 3294 DRSYLITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHT 3351 D + LITGG G +G A +L A G ++L SRR PD A + E+T + Sbjct: 3245 DGTVLITGGTGVLGGLVARHLVAGHGVRRLLLCSRRGPDAPGAVELVAELTALG-ADVTV 3303 Query: 3352 YAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS 3411 A D D +A LL + A PL G+ H AGV+DDA ++ PER L PK A Sbjct: 3304 AACDAADRDALAALLDTVPAT-HPLTGVVHTAGVIDDATVTTLTPERIDAVLRPKVDAAL 3362 Query: 3412 HXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGP 3471 + GQ NYA ANA LD L RRA GL A + +G Sbjct: 3363 NLHQLTAHLGLTRFVLFSSAAGLFGGAGQGNYAAANAFLDALAQHRRANGLNAQSLAWGL 3422 Query: 3472 WGQGGMASSEAATANITAQGLIPLDPSAALHALAEV-IANGSGQATVLKANWQRA---AK 3527 W + + A++ G L LA + A +AT++ A A+ Sbjct: 3423 WAEASGMTGHLDAADLARMGRSGLTAMPTGDGLALLDTAQRVDEATLVTAALDTRALHAR 3482 Query: 3528 VLGSARPPILDLVLP-------SAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQN 3580 P + ++P S A +A G L ++L + + +R + + + V Sbjct: 3483 AADGTLPALFHALVPVPRRSATSPAAQAAGPDGLRQRLSGLVVGERRAALLDLVCGHVAR 3542 Query: 3581 FLRLASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEY 3638 L A P + F D G DSL A+E RNRLH G + AT VFDYPT L ++ Sbjct: 3543 VLGHADPSSIEENKGFKDTGFDSLSAVEFRNRLHGATG--LRLPATLVFDYPTPAALTDH 3600 Query: 3639 LVGQL 3643 L +L Sbjct: 3601 LYDEL 3605 Score = 124 bits (310), Expect = 4e-25 Identities = 110/364 (30%), Positives = 157/364 (43%), Gaps = 19/364 (5%) Query: 3294 DRSYLITGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHT 3351 D + LITGG G +G A +L A G ++L SRR PD A + E+T + Sbjct: 1464 DGTVLITGGTGVLGGLVARHLVAGHGVRRLLLCSRRGPDAPGAVELVAELTALG-ADVTV 1522 Query: 3352 YAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGAS 3411 A D D +A LL + A PL G+ H AGV+DDA ++ PER L PK A Sbjct: 1523 AACDAADRDALAALLDTVPAT-HPLTGVVHTAGVIDDATVTTLTPERIDAVLRPKVDAAL 1581 Query: 3412 HXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGP 3471 + GQ NYA ANA LD L R+ QGL + +G Sbjct: 1582 NLHQLTAHLGLTRFVLFSSAAGLFGGAGQGNYAAANAFLDALAQLRKRQGLPGVSLAWGA 1641 Query: 3472 WGQ-GGMASSEAA--TANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKV 3528 W Q GGM ++ A + G++PL L+ +A ++ + A + Sbjct: 1642 WVQDGGMTATLDAGDVERMARGGVLPLSHEQGLNLFDLAVAGSEPLVAPMRLD-TTALRE 1700 Query: 3529 LGSARPPILDLVLPSAAGEATGDSE-------LLKQLMEIPIPQRAGFVTEFLQREVQNF 3581 G+ P +L ++ + G S L ++L + +R + + + V Sbjct: 1701 SGATVPEMLRGLVRERSRRRVGPSHTTSAAMALEQRLSGLVEGERRAALLDLVCGHVARV 1760 Query: 3582 LRLASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 L A P + F D G DSL A+ELRN LH G + AT VFDYPT L ++L Sbjct: 1761 LGHADPSSIEETRPFKDTGFDSLTAVELRNVLHGATG--LRLPATLVFDYPTPAALTDHL 1818 Query: 3640 VGQL 3643 +L Sbjct: 1819 YDEL 1822 >tr|C9YYI3|C9YYI3_STRSW Tax_Id=680198 SubName: Full=Putative type I polyketide synthase;[Streptomyces scabies] Length = 5001 Score = 1576 bits (4082), Expect = 0.0 Identities = 1089/3020 (36%), Positives = 1506/3020 (49%), Gaps = 172/3020 (5%) Query: 9 EPTPSFAIIGYAARFPGAASA-EEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGK 66 +P AI+ + RFPG E W LL DG E +S +P DR W ++ + PDP G Sbjct: 1621 DPDEPIAIVAMSCRFPGGIDTPERLWQLLIDGGEVLSGMPADRGWPLDRLYHPDPDHQGT 1680 Query: 67 VVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNT 126 R F+ D FD FFG+S RE MDPQ R+L+ET+W A E +GI P SL + T Sbjct: 1681 SYVREGSFLHDAGDFDPAFFGISPREAVAMDPQQRLLLETSWEAFERAGIDPASLRTTPT 1740 Query: 127 GVFVGLATHDYLGMASDELTYPEI-EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS 185 GVF G+ DY +A PE E ++ G + + +GR++Y LGL+GPAV VDTACS Sbjct: 1741 GVFAGVNYQDYTSLAGSS---PEGGEGHLVAGGAASVVSGRVAYTLGLEGPAVTVDTACS 1797 Query: 186 SSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGY 245 SSLVA H A QALR +C LALAGG V+ TP + FS LA DGRCK F A+ADG Sbjct: 1798 SSLVATHLAAQALRGGDCSLALAGGVAVMATPGVFVGFSRQRGLAADGRCKAFGASADGM 1857 Query: 246 VRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKR 305 EG GVV+++RL DA R+G + AV+RGSA+NQDGAS GL+ PNG+AQQRVI AL Sbjct: 1858 GLAEGVGVVLLERLSDARRNGHPVLAVLRGSAVNQDGASNGLSAPNGLAQQRVIRQALTN 1917 Query: 306 AGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXX 365 +GL ADV +EAHGTGT+LGDPIEA A G R PL +G+ K+NIGH + Sbjct: 1918 SGLTAADVDVVEAHGTGTTLGDPIEADALLATYGQDRPHGRPLRLGALKSNIGHTQAASG 1977 Query: 366 XXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFG 425 L + LP+ L+ + PSPH+ W +E++ E W G PR AG+SSFG Sbjct: 1978 VAGMIKTVLSLRHGVLPRTLHADEPSPHVDWASGEVELLTEARDWPDTGAPRRAGISSFG 2037 Query: 426 FAGTNAHVILEEAP----AVGTPATTEPVEDPRRYSVLP-----LSARTPEALVRLAGEY 476 F+GTN H ILE+AP AV A+ + +PR P LSAR+P+AL A Sbjct: 2038 FSGTNVHAILEQAPPVPEAVPGAASDDDGPEPRPAPGAPGVPWVLSARSPQALAHQAQRL 2097 Query: 477 RDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGE 536 R L D ++ T R E RA L+ E+ L LA A GL+RG Sbjct: 2098 RSHLAGGGAPDPLDTGYSLATGRTPFEHRAVLLGTGGEAPAAALDGLAGGEDAQGLIRGV 2157 Query: 537 SHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADE 596 + + ++F GQG+Q+ GMA EL DT PVFA ++ C +A+ P +D DA Sbjct: 2158 ADIDGRRVFVFPGQGAQWAGMAVELLDTSPVFAASIAACEQALT-----PYVDWSLDAVL 2212 Query: 597 LDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVE 656 P QPAL+AV + LA W+SWG EPD V+GHS G+ +AA VAG ++ Sbjct: 2213 RGAPDTPPFERVDVVQPALWAVMVSLAAQWRSWGVEPDAVLGHSQGEIAAAVVAGALSLD 2272 Query: 657 DGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPS-LSVAAYNGANTVL-SGPA 714 DGA+++A R R SL G M +V ERA L + LS+AA NG + V+ SG Sbjct: 2273 DGAKVVALRSRAILSLAGHGGMVSVAVPRERAVELVARWSGRLSLAAVNGPSAVVVSGDT 2332 Query: 715 KDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTG 774 + L +A +GVR + +A HSA ++ I ++ + + L TG Sbjct: 2333 EALTELIAACEEEGVRTRTIAVDYASHSAHVERIREEVLDALDGIVPVAGRVPLHSTLTG 2392 Query: 775 SALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLT--------ATA 826 L +T +D YW R+ R+ VEF +VR LAD +V +E+ P PVLT A Sbjct: 2393 DWLD-TTEMDAGYWYRNLRETVEFDGAVRALADQRHQVFVEVSPHPVLTMSVQETIEAAG 2451 Query: 827 LAAWPDPATTPQ--VLASLRPTTADHRQITEAVAAAYAAGHLPDFRA--FRQPDARKLDL 882 A + A P+ V +LR + + A + G +P F AR+ DL Sbjct: 2452 SAESAESAEAPRTVVTGTLRRDEGGLARALTSAAELWVRG-VPVLWPVLFEGTGARRTDL 2510 Query: 883 PTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAV-----RLLEDGQIEELAALIDG 937 PTYPFEHR++W + +A S T AV RL+E G E A + Sbjct: 2511 PTYPFEHRRYWLQ--------SAEPAAPSGTADEADAVDSAFWRLVERGDAAEAAGDL-- 2560 Query: 938 ETVDEQTL-RVLNKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILV---G 993 VD +TL VL L A +QR RY + W W++V G Sbjct: 2561 -AVDAETLGTVLPALNAWRRRQRQGAAVDTWRYRVDWQPVPDPPAAPLSGT-WLVVLPEG 2618 Query: 994 DDTAAVLEFAD----ALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGD 1049 D A ALT G V L +DAD L + L +A G ++ Sbjct: 2619 HDDVPGAPLAHDSVTALTEAGADVVTVRLTDTDADRVTLGERLTSALEGRTPHGILSLLA 2678 Query: 1050 GAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCL 1108 A P D V + L L +A D + +P+W T D+D + P+Q+ + Sbjct: 2679 IAGRPHPDHPAVSAGSALTLV-LVQALGDLGVEAPLWCATHGAVSTGDSDPLTAPDQALV 2737 Query: 1109 WGFGRAAALELPHIWGGLADLSGADTEWPR-LIARITSPRDGEDQIALRGDAVYAPRLVR 1167 WG G AALE P WGGL DL T R + + + GEDQ+A+R + RLVR Sbjct: 2738 WGTGMVAALEHPTRWGGLVDLPPTLTSLSRDRLRAVLAGATGEDQLAVRSAGLLGRRLVR 2797 Query: 1168 RTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXX 1227 P P + T LVTGG GA+G VA +LA GA H+VL RR Sbjct: 2798 APRPPGTRPA-WKPRGTVLVTGGTGALGPHVARWLARGGAEHLVLPGRRGADVPGADELR 2856 Query: 1228 XXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEV 1287 + + + DVAD VARL+T + E P+ + HAA I L+ LDD + Sbjct: 2857 AELAELGTRLSLPACDVADRAQVARLLTGLEEEGTPVTAVFHAAAYI---QLASLDDTPL 2913 Query: 1288 D---RVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLA 1344 D V A K GA HL E L +LD FV SS+A VWG AY A NA+LD LA Sbjct: 2914 DAFAEVVAAKAEGARHLDELLD---RELDAFVLFSSVAGVWGSSNHAAYTAGNAYLDALA 2970 Query: 1345 WRLRERGVTAVSVNFGPWAAG-------MADAESRARLEQRGVRTLSPAEALAGMADVVA 1397 R RG++A +V++G W+A D R++++G+ + P ALAG+ + Sbjct: 2971 EHRRARGLSATTVDWGVWSAANPWAVRETVDESDFYRVQKQGLPLIEPDLALAGLQQALD 3030 Query: 1398 GPVQGV-VAKIDWSRFLPLYQQAGRRAFLS---ELESELXXXXXXXXXXXXXXXXXXLVE 1453 V +A +DW +F ++ L+ E +L Sbjct: 3031 DDETVVALADVDWEQFAAVFGSVRPSRLLTGVPEARRQLEEAATPGASAATPAADVLRER 3090 Query: 1454 QLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGV 1513 A +QR+ + +A A + +E+R F +LG DSL AVELR R+ Sbjct: 3091 LAGLAGAEQRRVTLDLVRTHAAAVLGHDSPEELRPGRAFQELGFDSLTAVELRNRLRTAT 3150 Query: 1514 GKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQ-ASTVTARTDDPIAVVAVSCRFP 1572 G +P TLV D+P + A+++ EVLG R+ A T D+PIA+VA+SCRFP Sbjct: 3151 GLPLPATLVFDYPSAAVLAEHIRAEVLGEHRTPAGREPAPAGTGAADEPIAIVAMSCRFP 3210 Query: 1573 GAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXX 1630 G PE W LL G D + E P DR W ++ +DPDPD PG +Y R Sbjct: 3211 GGVHTPEQLWRLLEEGGDVVSEFPTDRGWPLESMFDPDPDQPGTSYVRHGGFLYDAGDFD 3270 Query: 1631 PEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLS 1690 +FFGISPREAV ++PQQRL+LET WE ERAG P LRG+ TGVFTGV +Y S Sbjct: 3271 ADFFGISPREAVAMDPQQRLLLETSWETFERAGLDPDRLRGTDTGVFTGVNYQDYG--AS 3328 Query: 1691 AESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDC 1750 + E H +TG+A + ISGR+++ LG EGPAV VDTACS++LVAVH A QAL++GDC Sbjct: 3329 VAQTQENEGHLLTGSAASVISGRISYTLGLEGPAVTVDTACSASLVAVHLAAQALRAGDC 3388 Query: 1751 DLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAV 1810 LALAGGV V+ SP +++ +R R L+ GRCK F +ADG +EG GV++L+RLS+A Sbjct: 3389 SLALAGGVAVMSSPGAIISFARQRGLAADGRCKAFSDAADGMGMAEGVGVILLERLSEAQ 3448 Query: 1811 RDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGT 1870 R G V AV+ S+VNQDGAS+GLT PNG +QQR+I A LA A LS A++D +E HGTGT Sbjct: 3449 RHGHPVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAALANARLSAAEIDVVETHGTGT 3508 Query: 1871 PLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQ 1930 LGDPIE Q PLL+GS+K+NIGHT++A+G AG+IK VL+L+HG +P+ Sbjct: 3509 RLGDPIEAQALLATYGRERSDGRPLLIGSLKSNIGHTQAAAGVAGVIKTVLALRHGQVPR 3568 Query: 1931 SLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLH 1990 +LH + PS + W A V V+ + PW GR RRAG+S+FG +GTN H +VEEAP + Sbjct: 3569 TLHVDRPSTQVDWTAGAVDVVTDTTPWPATGRPRRAGISAFGMSGTNVHAIVEEAPER-- 3626 Query: 1991 XXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTA 2050 P LSA+SP+AL A R L+ TPGL A + A Sbjct: 3627 --------SPRETPDEAPARPVAWPLSAKSPDALRGQAERLTAHLADTPGLPPAGI-GRA 3677 Query: 2051 GVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYP 2110 R+ FE+RA LV D+ P +VRG T ++F GQGSQ+ Sbjct: 3678 LTTRTAFEHRAVLVGDATRLPAALTALADDGTAP-DLVRGVADTVGRTVFVFPGQGSQWA 3736 Query: 2111 GMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAV 2170 GMAREL D PVFA + +C A+A + LLD + + QPALFAV Sbjct: 3737 GMARELLDESPVFAARMEECERALAPFVDWSLLDAV-----RSGGAWDRVDVVQPALFAV 3791 Query: 2171 EMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRM 2230 + LA +W+S+ + PD V+GHS G+ AAA VAG SL+DGA+++A R + +L G M Sbjct: 3792 MVSLAEVWRSFGVVPDAVVGHSQGEIAAAVVAGALSLEDGAQVVALRSKTLDALAGRGGM 3851 Query: 2231 VAVFADAEHVEQVAGEFP-RVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLAT 2288 ++ A+ E + +SV A NGP TV++G E L ++ + E +G+R + Sbjct: 3852 ASLSLPADRAEAALAPWAGALSVAALNGPATTVVAGDAEALAALLAQCEAQGVRARRIDV 3911 Query: 2289 SHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPV 2348 +A HSE ++ + +PL GA L T + A YW R+ RQ V Sbjct: 3912 DYASHSEHVEEIHGILMDALAGIKPLPSEVPLYSTVDGAWL-DTTGMHAGYWYRNLRQTV 3970 Query: 2349 QFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADA 2408 F +VR +AA G + +E+ P PVLT A + + +LR+ R++ + Sbjct: 3971 GFDPAVRVLAAEGFTSFVEVSPHPVLTMAIEETVETAGREAVVLGTLRRDEGGLRRVLLS 4030 Query: 2409 LASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDG-GTAASGILGSGK 2467 A +V G D+ A ELPTY FQRRR+W + + G G +LG+ Sbjct: 4031 AAELWVRGGAVDWTAAF-PGESTAELPTYAFQRRRYWIQPPAATPRGPGATGHPLLGTAV 4089 Query: 2468 DLA-SGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPA---RLKDVFF 2523 ++A +GD + T LS ++ PWLADH + G V++PG + +A+ A G A R++++ Sbjct: 4090 EVADTGDLVLTGSLSTRTHPWLADHAVSGVVLLPGTGFVELAVRA-GDEADCPRVEELTL 4148 Query: 2524 YEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDA 2583 P++ A+ ++Q+ + D + + SR G W+ +A G + AG+ A Sbjct: 4149 QAPLVFDRDAAVQIQVRVGAPDDSGRRTLGVFSRGEDGAGTPWTGHATGVLAPAGATDGA 4208 Query: 2584 A---------ADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDG 2634 A A + PVD L+E FAD +GP + G L++ W Sbjct: 4209 AHPYGAAWPPAGAEPVPVD------------GLYERFADAGYGYGPAFHG-LRAAWRLGQ 4255 Query: 2635 EAVGDILVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVT 2694 + ++ + + + +HP L+D LP + VT Sbjct: 4256 DVYVEVRLPEDQHTGAAAFGLHPALLDAALHGLWLATPDGADQGDEPGTARLPFAWEGVT 4315 Query: 2695 LAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLG 2754 L R + +T L D GR + + ++ +A LRG Sbjct: 4316 LHASGATELRVRLSY------DDTGSVALSAADPAGRPVADVTALAIRPIAVDA-LRGAA 4368 Query: 2755 GDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLS 2814 L+ L W + P +A++ VG W G G +P + + DL L+ Sbjct: 4369 AQGRDSLFRLDWTAL--PATAEEPVGRWAALG-------AGGLLP-ETHDDL----GALT 4414 Query: 2815 QAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLW 2874 A GA VV PG + + L + A L Sbjct: 4415 AAVDAGATVPDVVVTACPPG-------GNSADAARTALADTLRLLQAWLADDRWADTRLA 4467 Query: 2875 IVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXX 2933 ++T GVA GE + D AA+WG R+ +E P LVD + +++A+ Sbjct: 4468 LITRGGVATARGEDIGDLAAAAVWGLVRSAQSEHPDRFV-LVDAEDTADALRALPAAI-- 4524 Query: 2934 PGIQEPEIAVRQGKLLASRL 2953 EP++AVR G+ LA RL Sbjct: 4525 -AATEPQLAVRDGRTLAPRL 4543 Score = 1455 bits (3766), Expect = 0.0 Identities = 967/2536 (38%), Positives = 1304/2536 (51%), Gaps = 132/2536 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 A++ + FPG S E+ W L+ DGR+ S +P DR WD G V Sbjct: 39 AVVAMSCHFPGGVHSPEDLWDLVADGRDTYSGIPADRGWDAA-------GLAGSGVPVTG 91 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 F+D+ GFD FFG+S RE MDPQ R++++T W AVE GI P SL S TGVF Sbjct: 92 AFLDEAGGFDPAFFGISPREALAMDPQQRLMLQTCWEAVERGGIDPVSLRGSRTGVFAAS 151 Query: 133 ATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 Y+ +A PE ++ ++ G + + +GR+SY +GL+GP+V VDTACS+SLVA+ Sbjct: 152 IDQGYMSLADGA---PEGVQGFLMTGNAISVMSGRVSYVMGLEGPSVTVDTACSASLVAL 208 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A Q+LR +EC LAL GG NV+ P + S LA DGR K F AAADG GEG Sbjct: 209 HLAAQSLRNDECSLALVGGVNVMALPGAYVEISRQGGLAGDGRAKPFAAAADGTGWGEGI 268 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 GV++V+RL DA +G + AV+RGSAINQDGAS GLT PNG +QQRVI AL A L PA Sbjct: 269 GVLLVERLSDARANGHPVLAVLRGSAINQDGASNGLTAPNGPSQQRVIRAALADAQLAPA 328 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT LGDPIEA A G RA ++PL +GS K+NIGH + Sbjct: 329 DVDAVEAHGTGTRLGDPIEADALLAAYGQDRAEDQPLWLGSIKSNIGHTQAAAGLAGVIK 388 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 + + LP+ L+ + P+PH+ W + ++ E W + +PR AGVSSFG +GTNA Sbjct: 389 VVMAIRHGVLPQTLHVDAPTPHVDWSSGGVRLLTERRDWSVD-RPRRAGVSSFGMSGTNA 447 Query: 432 HVILEEAPAV------------GTPATTEPVEDPRRYSV--------------------- 458 HVI+E+AP G EP+ D +V Sbjct: 448 HVIIEQAPEAEQRPADEQAPEGGRQGAAEPIADAGPLTVPNAGSGLASGAEPDAAPLPTV 507 Query: 459 -LPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAI 517 PLS R+PEAL A WL P R ADV H+ R+ E RA +V + E + Sbjct: 508 PWPLSGRSPEALRDQAARLASWLADRPGLRPADVGHSLAATRSAFEHRAVVVADRPEGFL 567 Query: 518 ELLGALADDRPAPGLVRGESHEAP-KTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCA 576 L A+A A V G + +T ++F GQGSQ+ GMAR+L D PVFA + +C Sbjct: 568 RGLAAVAAGTSAAETVAGRTGAGDGRTVFVFPGQGSQWAGMARQLLDESPVFAARMAECE 627 Query: 577 EAVADILEKPLLDVIFDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVV 636 +A+A P LD A +PL QP LFAV + LA +W+S+G EPD V Sbjct: 628 QALA-----PHLDWSLSAVVRGEPDAAPLDRIDVVQPVLFAVMVSLAAVWRSYGVEPDAV 682 Query: 637 VGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAV-FTAPERAERLTDEY 695 VGHS G+ +AA VAG ++D AR++A R R L G MA+V A +RL Sbjct: 683 VGHSQGEIAAAYVAGALSLDDAARIVAVRSRAQLELSGTGGMASVALPADTLRDRLGAWE 742 Query: 696 PSLSVAAYNG-ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFES 754 LSVAA NG A+ V+SG + L+ + VR + A HSA +D + D Sbjct: 743 GRLSVAAVNGPASAVVSGDPEALDEFLRQCEERQVRTRRVAADVAGHSAHMDRLRDGLLD 802 Query: 755 FAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLL 814 + L TG +L +T +D YW R+ RQ VEF +VR L V + Sbjct: 803 ALAGVRPSAATIPLCSTVTGGSLD-TTGMDAGYWFRNMRQTVEFDAAVRDLVRRGHSVFV 861 Query: 815 EIGPRPVLTATALAAWPD--------PATTPQVLASLRPTTADHRQITEAVAAAYAAGHL 866 EI P PVLT D PA V +LR ++ A+A + G Sbjct: 862 EISPHPVLTVPTQDTLDDLADPDAAVPAPPTLVTGTLRRDEGGLHRVLTALAQVHVHGVP 921 Query: 867 PDFRA-FRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVT-PHRTQAVRLLE 924 D+ A F +++LPTY F++R+FW ++ T+ + T P +E Sbjct: 922 VDWAAVFAAHRPERVELPTYAFQNRRFW------LEPQTRPGTTRDTTDPADAAFWAAVE 975 Query: 925 DGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRWDXXXXXXXXXX 984 + E+AA + E VL L+A +R V RY I W Sbjct: 976 REDVAEVAATLGVEAASWSD--VLPALSAWRRDRRDRAVLDGWRYHISWQRLTAKAAAPL 1033 Query: 985 XXXDWILVGDD---TAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELY 1041 +LV D AAV +AL G ++V L S D ++L D LR Sbjct: 1034 RGRWPVLVPDGHTADAAVTRAVEALRERGADPELVVLDHSHTDRSRLTDHLREL------ 1087 Query: 1042 VVHIAAGDG---AAAPMRDLLRVQHRTLGGL----------RRLFRAANDAELRSPIWLV 1088 +A G G A A + LL + R GL L +A +D +R+ +W V Sbjct: 1088 ---LATGPGTETAPAGVLSLLALDERPHEGLPALPVGLALTTALVQALDDLGVRTTLWCV 1144 Query: 1089 TRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADL-SGADTEWPRLIARITSP 1146 T V ++ V P Q+ +WGFGR AALE P +WGGL DL D L+ + + Sbjct: 1145 TSGAVPVHPSEPVPHPVQALVWGFGRTAALEHPSLWGGLIDLPEQCDARAGHLLVDLLAG 1204 Query: 1147 RDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHG 1206 EDQ+A+R +A RLVR T P R T LVTGG G +G A +LA G Sbjct: 1205 AGDEDQLAVRSSGAHARRLVRATPSTPAPSDPWRPSGTVLVTGGTGGLGAHAARWLARGG 1264 Query: 1207 AGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAG 1266 A H+VL RR V + D+ D +A L+ VAAE P+ Sbjct: 1265 ADHLVLVGRRGADAPGADELAAELTALGTGVTLAACDITDREALAALVDRVAAEGHPVRA 1324 Query: 1267 IVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWG 1326 ++H A P+ + A + A KV GA +L L D TDLD FV SS++ VWG Sbjct: 1325 VLHTAAAAQLFPVRDENPASMAATLAAKVQGAANLDAVLAD--TDLDAFVLYSSVSGVWG 1382 Query: 1327 GFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAA---GMADAESRARLEQRGVRTL 1383 AY A NA+LD LA R RG+TA SV +G W+A G+A ++ L +RG+ + Sbjct: 1383 SADHAAYAAGNAYLDALAAHRRGRGLTATSVVWGIWSAEGGGLATSDLERALLERGIPFM 1442 Query: 1384 SPAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSEL---ESELXXXXXXX 1439 P A+ G+ V+ VVA +DW+RF+P++ +++L + Sbjct: 1443 DPRLAVGGLQRVLDDDETVVVVADVDWARFVPVFTSVRPSPLIADLPDVRALATAEDRTE 1502 Query: 1440 XXXXXXXXXXXLVEQLT-KAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMD 1498 L L A + R++L+ NA A + AD + + F +LG D Sbjct: 1503 PDPDDADGASALRRSLAGLAEPEVRRTLLDLVRTNAAAVLGHDSADAVLPDRAFRELGFD 1562 Query: 1499 SLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTART 1558 SL+AVELR R+ Q G + T+V D+ + A++L E+LG A A Sbjct: 1563 SLIAVELRNRLNQVTGLRLRATVVFDYSCAALLAEHLRTELLGDTAPAAATTAVVPVADP 1622 Query: 1559 DDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTY 1616 D+PIA+VA+SCRFPG D PE W+LL G + + +P DR W +D Y PDPD G +Y Sbjct: 1623 DEPIAIVAMSCRFPGGIDTPERLWQLLIDGGEVLSGMPADRGWPLDRLYHPDPDHQGTSY 1682 Query: 1617 TRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGV 1676 R P FFGISPREAV ++PQQRL+LET WE ERAG P+ LR + TGV Sbjct: 1683 VREGSFLHDAGDFDPAFFGISPREAVAMDPQQRLLLETSWEAFERAGIDPASLRTTPTGV 1742 Query: 1677 FTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALV 1736 F GV +Y L+ S + E H + G A + +SGRVA+ LG EGPAV VDTACSS+LV Sbjct: 1743 FAGVNYQDYTS-LAGSSPEGGEGHLVAGGAASVVSGRVAYTLGLEGPAVTVDTACSSSLV 1801 Query: 1737 AVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSE 1796 A H A QAL+ GDC LALAGGV V+ +P V SR R L+ GRCK F ASADG +E Sbjct: 1802 ATHLAAQALRGGDCSLALAGGVAVMATPGVFVGFSRQRGLAADGRCKAFGASADGMGLAE 1861 Query: 1797 GCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLS 1856 G GV++L+RLSDA R+G V AV+ S+VNQDGAS+GL+ PNG AQQR+I L +GL+ Sbjct: 1862 GVGVVLLERLSDARRNGHPVLAVLRGSAVNQDGASNGLSAPNGLAQQRVIRQALTNSGLT 1921 Query: 1857 GADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGL 1916 ADVD +EAHGTGT LGDPIE PL +G++K+NIGHT++ASG AG+ Sbjct: 1922 AADVDVVEAHGTGTTLGDPIEADALLATYGQDRPHGRPLRLGALKSNIGHTQAASGVAGM 1981 Query: 1917 IKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGT 1976 IK VLSL+HGVLP++LH + PSPH+ W + V ++ E W G RRAG+SSFGF+GT Sbjct: 1982 IKTVLSLRHGVLPRTLHADEPSPHVDWASGEVELLTEARDWPDTGAPRRAGISSFGFSGT 2041 Query: 1977 NAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV-LALSARSPEALVELARRYDDWL 2035 N H ++E+APP +P V LSARSP+AL A+R L Sbjct: 2042 NVHAILEQAPPVPEAVPGAASDDDGPEPRPAPGAPGVPWVLSARSPQALAHQAQRLRSHL 2101 Query: 2036 SATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHR 2095 + D D ++ GR+ FE+RA L+ G++RG Sbjct: 2102 AGGGAPDPLDTGYSLATGRTPFEHRAVLLGTGGEAPAAALDGLAGGEDAQGLIRGVADID 2161 Query: 2096 PTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETAD 2155 ++F GQG+Q+ GMA EL DT PVFA ++ C +A+ + LD + +T Sbjct: 2162 GRRVFVFPGQGAQWAGMAVELLDTSPVFAASIAACEQALTPYVDWS-LDAVLRGAPDTPP 2220 Query: 2156 LLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMA 2215 + QPAL+AV + LA W+SW +EPD VLGHS G+ AAA VAG SLDDGA+++A Sbjct: 2221 -FERVDVVQPALWAVMVSLAAQWRSWGVEPDAVLGHSQGEIAAAVVAGALSLDDGAKVVA 2279 Query: 2216 ERGRMFGSLPEGGRMVAVFADAEH-VEQVAGEFPRVSVGAYNGPN-TVLSGPGEDLEEIV 2273 R R SL G MV+V E VE VA R+S+ A NGP+ V+SG E L E++ Sbjct: 2280 LRSRAILSLAGHGGMVSVAVPRERAVELVARWSGRLSLAAVNGPSAVVVSGDTEALTELI 2339 Query: 2274 ERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQT 2333 E+EG+R +A +A HS ++ + + +PL TG L T Sbjct: 2340 AACEEEGVRTRTIAVDYASHSAHVERIREEVLDALDGIVPVAGRVPLHSTLTGDWL-DTT 2398 Query: 2334 PLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLT--------GAAVQVWPEH 2385 +DA YW R+ R+ V+F +VR +A V +E+ P PVLT A E Sbjct: 2399 EMDAGYWYRNLRETVEFDGAVRALADQRHQVFVEVSPHPVLTMSVQETIEAAGSAESAES 2458 Query: 2386 MAAPRAV--ASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRR 2442 APR V +LR+ + + A +V G + + R +LPTYPF+ R Sbjct: 2459 AEAPRTVVTGTLRRDEGGLARALTSAAELWVRGVPVLWPVLFEGTGARRTDLPTYPFEHR 2518 Query: 2443 RFWPKASSIAVDGGTA 2458 R+W +++ A GTA Sbjct: 2519 RYWLQSAEPAAPSGTA 2534 Score = 617 bits (1590), Expect = e-173 Identities = 397/956 (41%), Positives = 521/956 (54%), Gaps = 60/956 (6%) Query: 1533 DYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAI 1591 DYL + L Q R+ V R+ +PIAVVA+SC FPG PE W+L+A G D Sbjct: 11 DYLNRVTIDL--QQTRRRLRDVEERSREPIAVVAMSCHFPGGVHSPEDLWDLVADGRDTY 68 Query: 1592 REVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRL 1650 +P DR WD G P FFGISPREA+ ++PQQRL Sbjct: 69 SGIPADRGWDAAGLAGSGVPVTGAFLDEAGGFD-------PAFFGISPREALAMDPQQRL 121 Query: 1651 MLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAI 1710 ML+T WE +ER G P LRGSRTGVF Y L + ++ +TGNA++ + Sbjct: 122 MLQTCWEAVERGGIDPVSLRGSRTGVFAASIDQGYMSLADGAP-EGVQGFLMTGNAISVM 180 Query: 1711 SGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAA 1770 SGRV++ +G EGP+V VDTACS++LVA+H A Q+L++ +C LAL GGVNV+ P V Sbjct: 181 SGRVSYVMGLEGPSVTVDTACSASLVALHLAAQSLRNDECSLALVGGVNVMALPGAYVEI 240 Query: 1771 SRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGA 1830 SR L+ GR K F A+ADG EG GVL+++RLSDA +G V AV+ S++NQDGA Sbjct: 241 SRQGGLAGDGRAKPFAAAADGTGWGEGIGVLLVERLSDARANGHPVLAVLRGSAINQDGA 300 Query: 1831 SSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXX 1890 S+GLT PNG +QQR+I A LA A L+ ADVD +EAHGTGT LGDPIE Sbjct: 301 SNGLTAPNGPSQQRVIRAALADAQLAPADVDAVEAHGTGTRLGDPIEADALLAAYGQDRA 360 Query: 1891 XXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRV 1950 PL +GS+K+NIGHT++A+G AG+IKVV++++HGVLPQ+LH + P+PH+ W + VR+ Sbjct: 361 EDQPLWLGSIKSNIGHTQAAAGLAGVIKVVMAIRHGVLPQTLHVDAPTPHVDWSSGGVRL 420 Query: 1951 IDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAP---------------------PQL 1989 + E W + R RRAGVSSFG +GTNAHV++E+AP P Sbjct: 421 LTERRDWSVD-RPRRAGVSSFGMSGTNAHVIIEQAPEAEQRPADEQAPEGGRQGAAEPIA 479 Query: 1990 HXXXXXXXXXXXXXXXGTDDSPQVL-----ALSARSPEALVELARRYDDWLSATPGLDIA 2044 G + L LS RSPEAL + A R WL+ PGL A Sbjct: 480 DAGPLTVPNAGSGLASGAEPDAAPLPTVPWPLSGRSPEALRDQAARLASWLADRPGLRPA 539 Query: 2045 DVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGE-HVHRPTTAWLFT 2103 DV H+ RS FE+RA +V D + A V G T ++F Sbjct: 540 DVGHSLAATRSAFEHRAVVVADRPEGFLRGLAAVAAGTSAAETVAGRTGAGDGRTVFVFP 599 Query: 2104 GQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFA 2163 GQGSQ+ GMAR+L D PVFA + +C +A+A L L V+ A L Sbjct: 600 GQGSQWAGMARQLLDESPVFAARMAECEQALAPHLDWSLSAVV--RGEPDAAPLDRIDVV 657 Query: 2164 QPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGS 2223 QP LFAV + LA +W+S+ +EPD V+GHS G+ AAA VAG SLDD AR++A R R Sbjct: 658 QPVLFAVMVSLAAVWRSYGVEPDAVVGHSQGEIAAAYVAGALSLDDAARIVAVRSRAQLE 717 Query: 2224 LPEGGRMVAVFADAEHVEQVAGEFP-RVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGI 2281 L G M +V A+ + G + R+SV A NGP + V+SG E L+E + + E+ + Sbjct: 718 LSGTGGMASVALPADTLRDRLGAWEGRLSVAAVNGPASAVVSGDPEALDEFLRQCEERQV 777 Query: 2282 RCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWR 2341 R +A A HS +D + D T+PL TG L T +DA YW Sbjct: 778 RTRRVAADVAGHSAHMDRLRDGLLDALAGVRPSAATIPLCSTVTGGSL-DTTGMDAGYWF 836 Query: 2342 RHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRA---------V 2392 R+ RQ V+F +VR + G SV +EI P PVLT Q + +A P A Sbjct: 837 RNMRQTVEFDAAVRDLVRRGHSVFVEISPHPVLT-VPTQDTLDDLADPDAAVPAPPTLVT 895 Query: 2393 ASLRKGVADRRQIADALASAYVGGHRPDFAAV---HRQPRRPVELPTYPFQRRRFW 2445 +LR+ ++ ALA +V G D+AAV HR R VELPTY FQ RRFW Sbjct: 896 GTLRRDEGGLHRVLTALAQVHVHGVPVDWAAVFAAHRPER--VELPTYAFQNRRFW 949 Score = 141 bits (356), Expect = 2e-30 Identities = 148/514 (28%), Positives = 209/514 (40%), Gaps = 59/514 (11%) Query: 1047 AGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVVP-EQ 1105 + D A + D LR+ L A+D + + L+TR G + + Sbjct: 4437 SADAARTALADTLRLLQAWL---------ADDRWADTRLALITRGGVATARGEDIGDLAA 4487 Query: 1106 SCLWGFGRAAALELPH--IWGGLADLSGADTEWPRLIARITSPRDGEDQIALRGDAVYAP 1163 + +WG R+A E P + D + A P IA E Q+A+R AP Sbjct: 4488 AAVWGLVRSAQSEHPDRFVLVDAEDTADALRALPAAIAAT------EPQLAVRDGRTLAP 4541 Query: 1164 RLVRR--TGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRREPXX 1220 RL R TG P + T LVTG G +G VA +L + HG H++LT RR Sbjct: 4542 RLTRTPATGTDGGAGKPWDPEGTVLVTGAFGVLGGLVARHLVTGHGVRHLLLTGRRGADT 4601 Query: 1221 XXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLS 1280 VR D AD VA L+ VA + PL +VH+AG + + Sbjct: 4602 PEANALVDELTALGAQVRAAACDTADRDAVAALLAGVADD-HPLTAVVHSAGTLDDGVIG 4660 Query: 1281 GLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFL 1340 L +D V K A +L E DL L FV SS + G GQ Y AANAFL Sbjct: 4661 SLTPERLDHVLRPKADAALNLHELTRDL--PLAAFVLFSSASGTVGSSGQGNYAAANAFL 4718 Query: 1341 DGLAWRLRERGVTAVSVNFGPWA-----AGMADAESRARLEQRGVRTLSPAEALA----- 1390 D LA R +G+ S+ +G WA G D R+ + GV L+ E LA Sbjct: 4719 DALAQHRRAQGLPGQSLAWGMWAERSTLTGTLDEVDLRRIARGGVGALTSDEGLALFDTA 4778 Query: 1391 -GMADVVAGPVQGVVAKIDW--------SRFLPLYQQAGRRAFLSELESELXXXXXXXXX 1441 + D V PV+ +A++ + F L + A RR S +++ Sbjct: 4779 LELDDAVLVPVRIDLARMRARAGNAAVPALFRALVRGAVRRTAASGADTD---------- 4828 Query: 1442 XXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSL 1500 L +L ++++ + + A+V A + E F LG DSL Sbjct: 4829 -----GADALRRRLAGLAADDARTVLADLVCAHAADVLGHAGASAVDPERAFRQLGFDSL 4883 Query: 1501 MAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADY 1534 AVELR R+ G +P TLV D+P + A Y Sbjct: 4884 TAVELRNRLNAATGLRLPATLVFDYPSPAAVAGY 4917 Score = 137 bits (344), Expect = 4e-29 Identities = 112/372 (30%), Positives = 157/372 (42%), Gaps = 20/372 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG G +G H A +LA+ GA +VL RR D + + A D+ Sbjct: 1244 LVTGGTGGLGAHAARWLARGGADHLVLVGRRGADAPGADELAAELTALGTGVTLAACDIT 1303 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A L+ R+ AE P+ + H A + +NP TLA K GA++ Sbjct: 1304 DREALAALVDRVAAEGHPVRAVLHTAAAAQLFPVRDENPASMAATLAAKVQGAANLDAVL 1363 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ--G 3475 A YA NA LD L A RR +GL AT + +G W G Sbjct: 1364 ADTDLDAFVLYSSVSGVWGSADHAAYAAGNAYLDALAAHRRGRGLTATSVVWGIWSAEGG 1423 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP 3535 G+A+S+ A + +G+ +DP A+ L V+ + V +W R V S RP Sbjct: 1424 GLATSDLERA-LLERGIPFMDPRLAVGGLQRVLDDDETVVVVADVDWARFVPVFTSVRPS 1482 Query: 3536 ILDLVLPSAAGEAT-------------GDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL 3582 L LP AT G S L + L + P+ + + ++ L Sbjct: 1483 PLIADLPDVRALATAEDRTEPDPDDADGASALRRSLAGLAEPEVRRTLLDLVRTNAAAVL 1542 Query: 3583 RLASPPAA--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLV 3640 S A F +LG DSL+A+ELRNRL+ G + AT VFDY LAE+L Sbjct: 1543 GHDSADAVLPDRAFRELGFDSLIAVELRNRLNQVTG--LRLRATVVFDYSCAALLAEHLR 1600 Query: 3641 GQLPDAEAPETA 3652 +L AP A Sbjct: 1601 TELLGDTAPAAA 1612 Score = 130 bits (328), Expect = 3e-27 Identities = 108/361 (29%), Positives = 155/361 (42%), Gaps = 22/361 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA+ GA +VL RR D + R+ A DV Sbjct: 2815 LVTGGTGALGPHVARWLARGGAEHLVLPGRRGADVPGADELRAELAELGTRLSLPACDVA 2874 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D AQVA LL + E P+ + H A + A L + F +A KA GA H Sbjct: 2875 DRAQVARLLTGLEEEGTPVTAVFHAAAYIQLASLDDTPLDAFAEVVAAKAEGARH-LDEL 2933 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG- 3476 A Y NA LD L RRA+GL AT +++G W Sbjct: 2934 LDRELDAFVLFSSVAGVWGSSNHAAYTAGNAYLDALAEHRRARGLSATTVDWGVWSAANP 2993 Query: 3477 ----MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA 3532 E+ + QGL ++P AL L + + + + +W++ A V GS Sbjct: 2994 WAVRETVDESDFYRVQKQGLPLIEPDLALAGLQQALDDDETVVALADVDWEQFAAVFGSV 3053 Query: 3533 RPPILDLVLPSA-----------AGEATGDSELLKQ-LMEIPIPQRAGFVTEFLQREVQN 3580 RP L +P A A AT +++L++ L + ++ + ++ Sbjct: 3054 RPSRLLTGVPEARRQLEEAATPGASAATPAADVLRERLAGLAGAEQRRVTLDLVRTHAAA 3113 Query: 3581 FLRLASPP--AASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEY 3638 L SP F +LG DSL A+ELRNRL + G + AT VFDYP+ LAE+ Sbjct: 3114 VLGHDSPEELRPGRAFQELGFDSLTAVELRNRLRTATG--LPLPATLVFDYPSAAVLAEH 3171 Query: 3639 L 3639 + Sbjct: 3172 I 3172 Score = 118 bits (296), Expect = 2e-23 Identities = 105/368 (28%), Positives = 149/368 (40%), Gaps = 19/368 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQ-LGAGDIVLTSRRDPDE-SAQRAIDEITERHKCRIHTYAAD 3355 L+TG G +G A +L G ++LT RR D A +DE+T ++ A D Sbjct: 4566 LVTGAFGVLGGLVARHLVTGHGVRHLLLTGRRGADTPEANALVDELTALG-AQVRAAACD 4624 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 D VA LLA + A+ PL + H AG LDD ++ + PER L PKA A + Sbjct: 4625 TADRDAVAALLAGV-ADDHPLTAVVHSAGTLDDGVIGSLTPERLDHVLRPKADAALNLHE 4683 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQ NYA ANA LD L RRAQGL + +G W + Sbjct: 4684 LTRDLPLAAFVLFSSASGTVGSSGQGNYAAANAFLDALAQHRRAQGLPGQSLAWGMWAER 4743 Query: 3476 GMAS---SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA 3532 + E I G+ L L + ++ + R G+A Sbjct: 4744 STLTGTLDEVDLRRIARGGVGALTSDEGLALFDTALELDDAVLVPVRIDLARMRARAGNA 4803 Query: 3533 RPPILDLVL--------PSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL 3584 P L L ++ + G L ++L + + + + + L Sbjct: 4804 AVPALFRALVRGAVRRTAASGADTDGADALRRRLAGLAADDARTVLADLVCAHAADVLGH 4863 Query: 3585 ASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ 3642 A A F LG DSL A+ELRNRL++ G + AT VFDYP+ +A Y + Sbjct: 4864 AGASAVDPERAFRQLGFDSLTAVELRNRLNAATG--LRLPATLVFDYPSPAAVAGYCAER 4921 Query: 3643 LPDAEAPE 3650 L A AP+ Sbjct: 4922 LAPAGAPQ 4929 Score = 52.0 bits (123), Expect = 0.002 Identities = 47/143 (32%), Positives = 57/143 (39%), Gaps = 20/143 (13%) Query: 2873 LWIVTEHGVACESGEPVD-PVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXX 2931 LW VT V EPV PVQA +WGFGRT E P+L L+D +A Sbjct: 1141 LWCVTSGAVPVHPSEPVPHPVQALVWGFGRTAALEHPSLWGGLIDLPEQCDARAGHLLVD 1200 Query: 2932 XXPGI-QEPEIAVRQGKLLASRLL-----------PWARSGHLTLPRG----GDFVLAPT 2975 G E ++AVR A RL+ PW SG + + G G Sbjct: 1201 LLAGAGDEDQLAVRSSGAHARRLVRATPSTPAPSDPWRPSGTVLVTGGTGGLGAHAARWL 1260 Query: 2976 ERGAIDNLRLT---ETDVPEPDE 2995 RG D+L L D P DE Sbjct: 1261 ARGGADHLVLVGRRGADAPGADE 1283 Score = 48.5 bits (114), Expect = 0.020 Identities = 78/288 (27%), Positives = 101/288 (35%), Gaps = 53/288 (18%) Query: 2762 YTLGWHEVPPPPSADDAVGTWLIA---GFD----------------ELAAKVPGCVPIDR 2802 Y + W VP PP+A + GTWL+ G D E A V D Sbjct: 2592 YRVDWQPVPDPPAAPLS-GTWLVVLPEGHDDVPGAPLAHDSVTALTEAGADVVTVRLTDT 2650 Query: 2803 NTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAA 2862 + D LGE L+ A G G++ A GR + V A Sbjct: 2651 DADRVTLGERLTSA-LEGRTPHGILSLLAIAGRPHPDHPAVSAGSALTLVL-----VQAL 2704 Query: 2863 QGPSVKLPGGLWIVTEHGVACESGEPVD-PVQAALWGFGRTTINEEPALHCRLVDCDGSS 2921 V+ P LW T V+ +P+ P QA +WG G E P LVD + Sbjct: 2705 GDLGVEAP--LWCATHGAVSTGDSDPLTAPDQALVWGTGMVAALEHPTRWGGLVDLPPTL 2762 Query: 2922 EAVDXXXXXXXXPGIQ-EPEIAVRQGKLLASRLL----------PWARSGHLTLPRGGDF 2970 ++ G E ++AVR LL RL+ W G L GG Sbjct: 2763 TSLSRDRLRAVLAGATGEDQLAVRSAGLLGRRLVRAPRPPGTRPAWKPRG-TVLVTGGTG 2821 Query: 2971 VLAP-----TERGAIDNLRL---TETDVPEPDEGYVQVRVEAAGLNFR 3010 L P RG ++L L DVP DE +R E A L R Sbjct: 2822 ALGPHVARWLARGGAEHLVLPGRRGADVPGADE----LRAELAELGTR 2865 >tr|Q8GBX5|Q8GBX5_SORCE Tax_Id=56 (spiI)SubName: Full=Polyketide synthase;[Sorangium cellulosum] Length = 3513 Score = 1569 bits (4063), Expect = 0.0 Identities = 1121/3044 (36%), Positives = 1494/3044 (49%), Gaps = 174/3044 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + RFPG A S E+ W LL GR+A+S P R W +E DP GK Sbjct: 41 AIVAMSCRFPGGARSPEDLWQLLEGGRDAVSGFPASRGWSVEPRVDPRADVTGKTPALEG 100 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF++ FDA FFG+S RE MDPQ R+L+ET W A+E + I P SL S TGVFVG+ Sbjct: 101 GFLEGAELFDAAFFGVSPREALEMDPQQRLLLETTWEAIERAEIDPASLQGSQTGVFVGV 160 Query: 133 ATHDYLGMASDELTYP-EIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 ++Y AS L + Y++ +S + A+GRI+Y G GP V VDTACSSSLVA+ Sbjct: 161 MYNNY---ASHHLGGDGDASGYVSFASSASVASGRIAYTFGFHGPTVTVDTACSSSLVAV 217 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H ACQALR EC LALAGG V+ T S A +PDGRCK+F A A+G EG Sbjct: 218 HLACQALRSGECALALAGGVTVMATREAFDALSFAG--SPDGRCKSFSADANGAGWSEGA 275 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 G+V+++RL DA R+G I AVIRGSA+NQDG S GLT PNG AQ+RVI AL A L Sbjct: 276 GMVLLERLSDAQRNGHPILAVIRGSAVNQDGKSQGLTAPNGPAQERVIRQALAAARLETH 335 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 D+ +EAHGTGT LGDPIEA A G GR E PL +GS K+N+GH + Sbjct: 336 DIDAVEAHGTGTPLGDPIEANALLATYGLGRPAERPLWLGSLKSNVGHTQAAAGVGGIIK 395 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 L N LP+ L+ PSPH+ W + ++ + VPW RNG+ R A VSSFG +GTNA Sbjct: 396 TVLALRNGLLPRTLHAHAPSPHVDWAAGGLRLLADAVPWTRNGRVRRAAVSSFGLSGTNA 455 Query: 432 HVILEEAPAVGTPATTEPVEDPR-RYSVLP--LSARTPEALVRLAGEYRDWLRAHPQARL 488 HVI+EEAP P E P R LP LSA+T +AL A L P A L Sbjct: 456 HVIVEEAPR---PDRDEASPAPSGRDQALPVLLSAKTEDALRAQAARLHAHLAGDPGASL 512 Query: 489 ADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDR-PAPGLVRGESHEAP-KTAWL 546 DV+ + T RAH + RAA V SR++ + L A A AP V + AP K A L Sbjct: 513 VDVAASLATTRAHFDHRAAFVARSRDALLAALDAFARGAIDAPASVASVARRAPTKLALL 572 Query: 547 FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLR 606 FTGQGSQ P M R L+D P F + + A L++PLLDV+F + + L Sbjct: 573 FTGQGSQRPAMGRGLYDAFPAFRDALDAVASHFDRELDRPLLDVLFAPG--GSELAALLD 630 Query: 607 HTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERG 666 T + QPALFA+E+ L RL ++ G PD ++GHS+G+ AA VAGV +ED L+A R Sbjct: 631 ETLFTQPALFALEVALFRLVEACGLRPDALLGHSIGELVAAHVAGVLSLEDACTLVAARA 690 Query: 667 RLFGSLPAGGRMAAVFTAPERA--ERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVAT 723 RL +LP A ER + L+ + +AA NG A+ V+SG + + A+ Sbjct: 691 RLMHALPPRDAAMVALNASEREVLDVLSAHPTGVGIAAVNGPASVVVSGDEDAVLAVAAS 750 Query: 724 LVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRL 783 A G + L SHAFHS +DP+L+ F A+ L + P+ ++ N TG+ Sbjct: 751 FQARGRKTSRLRVSHAFHSHHMDPLLEAFRRVAEGLTFHPPRIPIVSNVTGARAEEGELT 810 Query: 784 DGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLA-- 841 YW RH R V FA V+ L LE+GP VL A AA + P+ A Sbjct: 811 SPDYWVRHVRGAVRFADGVQALRADGVSSFLELGPHGVLCALGSAALQEDRPPPEGAAFV 870 Query: 842 -SLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDA-RKLDLPTYPFEHRQFWFSDNRA 899 +LR AD A+ A Y G D+RA P A R++ LPTY F+ +FW A Sbjct: 871 PALRAERADDDAFAAALGALYTRGLTLDWRALFAPFAPRRVPLPTYAFQRDRFWLEAASA 930 Query: 900 IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTL-RVLNKLAARHNQQ 958 + + A T R ++ G ++ ++A + + D + L A ++ Sbjct: 931 QPAEPRAAE-------ETALWRAIDRGDVDAISAELRVDDADHRAAWATLVPTLAAWRRE 983 Query: 959 RSTHVDPDA-RYEIRWDXXXXXXXXXXXXXDWILV--GDDTAAVLEFADALTAGGHRHQI 1015 R H DA RY + W W++V G + A AL+A G Sbjct: 984 RRAHATLDAWRYRVVW-RPCTIAPGASVEGTWLVVIPGVASDVARPLARALSARGAAVVE 1042 Query: 1016 VALPGS--DADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLF 1073 + + D L +RAASA + + A LG L Sbjct: 1043 IEIAAGLEGVDREALAARVRAASADSRAIRGVLALTALDERPLAAHPAVPAGLGATLALV 1102 Query: 1074 RAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLSGA 1132 +A D + +P+WLVTR + +D + P Q+ WG GR ALE P WGG DL+ Sbjct: 1103 QALGDLAIDAPLWLVTRGAVSIGRSDPIASPVQAMSWGLGRVVALEHPARWGGAIDLAAG 1162 Query: 1133 DTE-------WPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTY 1185 D RL+A + + RDGEDQ+ALR +YA RLVR + T Sbjct: 1163 DPAAALDARALERLVAALAT-RDGEDQLALRPAGLYARRLVRAKIGDAAPARAFAPAGTV 1221 Query: 1186 LVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVA 1245 LVTGG GA+G VA +LA GA H+VLTSRR V + DVA Sbjct: 1222 LVTGGTGALGAHVARWLAKSGAEHLVLTSRRGRSAPGAEALQAELTALGARVTIAACDVA 1281 Query: 1246 DAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEAL 1305 D L+ + A+ PL +VHA G TPL ++ R AGK GA +L E L Sbjct: 1282 DRDAFGALLRDLEAQGSPLRAVVHAGGAAQGTPLDATSLDDLTRAIAGKAAGARNLDE-L 1340 Query: 1306 TDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG 1365 T R LD FV +S A VWGG Q AY AANAFLD LA R RG+TA S+ +G WA G Sbjct: 1341 TGERA-LDAFVLFASGAGVWGGGHQGAYAAANAFLDALAESRRARGLTATSIAWGAWAGG 1399 Query: 1366 MADAESRA---RLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQAGR 1421 AE A L +RG+ ++P A+A +A + V +A +DW+RF P A Sbjct: 1400 GMLAEDPAAEEHLRRRGLPPMAPELAIAALARALDHDDTNVTIADVDWARFAPSLASARS 1459 Query: 1422 RAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQR-KSLITNYLRNAVAEVTR 1480 R L +L L+ L P R + L+ ++ + Sbjct: 1460 RPLLHDLSEAKRALDARPEAAQGRDGEPELLATLRPLPAGDRLRHLVALVVKETALVLGH 1519 Query: 1481 VDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAA----DYLL 1536 D + GFFD G+DSLMAV+LR R+++ G +P T+ DHP D A D L Sbjct: 1520 ADVARVEPRRGFFDSGLDSLMAVDLRVRLQRATGVTLPATVTFDHPCPHDLAAHLCDALA 1579 Query: 1537 VEVLGLGEQTNVRQASTVTART--DDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIRE 1593 + + G G +VR ++ A + D+PIA+V + R PG D ++ + LL G DA+ Sbjct: 1580 LPLDGAGRD-DVRAVASARAPSPSDEPIAIVGLGLRLPGGVGDMDALFRLLEEGRDAVGP 1638 Query: 1594 VPEDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLE 1653 +P++RWD D YDPDP+ GK+Y R FFGISPREA I+PQ RL+LE Sbjct: 1639 IPKERWDADAIYDPDPEAKGKSYVRDAALIDRVDLFDAAFFGISPREAKQIDPQHRLLLE 1698 Query: 1654 TVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGR 1713 T W+ LE AG P+ L+ + TGVF G A++YA L S E + G A + +GR Sbjct: 1699 TAWQALEDAGIVPASLKDTSTGVFVGAGASDYAFLQGTPS--DAEAYAAMGTAFSFTAGR 1756 Query: 1714 VAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRA 1773 +AF LG +GPA+A+DTACSS+LVA+H ACQ+L+ G+CDLALA G V SP + SR Sbjct: 1757 LAFTLGLQGPALAIDTACSSSLVALHLACQSLRRGECDLALAAGSQVTASPDVFILLSRT 1816 Query: 1774 RMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSG 1833 R L+ GR KTF A ADGY R EG VL L+RL DA G RV AV+ ++VN DGASSG Sbjct: 1817 RALAADGRSKTFSAHADGYGRGEGVVVLALERLRDAEARGHRVLAVVRGTAVNHDGASSG 1876 Query: 1834 LTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXX 1893 +T PNG +QQ+++ A L AGL+ ADVD +E HGTGT LGDPIEVQ Sbjct: 1877 ITAPNGTSQQKVLRAALGDAGLAPADVDVVECHGTGTALGDPIEVQALAAVYGEGRAPER 1936 Query: 1894 PLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDE 1953 PLL+G+VKTNIGH E+ASG AG+ K+V ++QH LP + +PHI W +LPV V+ Sbjct: 1937 PLLLGAVKTNIGHLEAASGLAGVAKIVAAMQHATLPATRGTTPLNPHIHWASLPVSVVGA 1996 Query: 1954 PVPWQTNGR--VRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSP 2011 PW+ RRAGVS+FG +GTNAHV+VEEA P D P Sbjct: 1997 TRPWRRRDEETPRRAGVSAFGLSGTNAHVIVEEA-PLARAAKPCATATGADGAAPRDGGP 2055 Query: 2012 QVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXX 2071 + LSA++ AL A R L A G +ADV + RSHFE+RAA+V Sbjct: 2056 VPVLLSAKTEAALRAQAERLGAHLDAHAGAALADVAASLATTRSHFEHRAAIVAGDRDAL 2115 Query: 2072 XXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCA 2131 + V+ G V A LFTGQG Q M R L+ VF Sbjct: 2116 RDALAAVAEGRSAPRVLVGRAVAGGKLALLFTGQGGQRAAMGRGLYGAFSVFRDAFDAAC 2175 Query: 2132 EAVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLG 2190 + L PL DV+FA + A LL T + Q +LFA+E+ L RL ++W + P V+LG Sbjct: 2176 SYLDRELEHPLRDVVFAPRGADLAALLDETLYTQTSLFALEVALFRLVEAWGVTPHVLLG 2235 Query: 2191 HSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLP-EGGRMVAVFADAEHV----EQVAG 2245 HS+G+ AA VAGV SL+D L+A R R+ +LP MVAV A V + +AG Sbjct: 2236 HSIGELVAAHVAGVLSLEDACTLVAARARLMHALPRRDAAMVAVHACEREVLDALDAMAG 2295 Query: 2246 EFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXX 2304 R S+ A N P +TV++G E + + RFE G + + L SHAFHS LDP+L+ Sbjct: 2296 LDGRASIAAVNAPSSTVVAGDREAVLAVAARFEALGRKTSRLRVSHAFHSHHLDPMLEAF 2355 Query: 2305 XXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSV 2364 P +P+V N TGA + A YW RH+R V+FA+ + + A G S Sbjct: 2356 RRVAEGVRFQPPRIPIVSNVTGARASNDDLCSAAYWVRHARGTVRFADGLEALRADGVST 2415 Query: 2365 LMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAV 2424 +E+GP VL + A + +LR G D + AL + + GH D+ A Sbjct: 2416 FLELGPHAVLCALGHETLGSEAVA--FLPALRDGRDDVDTLTAALGALHARGHHVDWDAF 2473 Query: 2425 HRQ-PRRPVELPTYPFQRRRFW---PKASSIAVDGGTAAS--GILGSGKDLASGDTIYTS 2478 V LPTY FQR RFW PKA S V +A + G+ DL G ++T Sbjct: 2474 FAPFNAGRVTLPTYAFQRERFWLDMPKAKSSRVAAADSAGRYPLAGTRLDLPDGSAVHTL 2533 Query: 2479 RLSVKSQPWLADHVIYGTVVVPGATYAAMALAAV-----GTPARLKDVFFYEPIILPEKA 2533 + +QP+LADH +YG +VVPGA Y A+ LA +P L+DV F + + Sbjct: 2534 DIGPGAQPYLADHSVYGRIVVPGAFYVAIFLAVAESHWPDSPLELRDVEFVRALSFQHAS 2593 Query: 2534 ---SREVQLTLHPADGGSVLSFQIHSRPYGERGAD-WSLNAEGTVDTAGSDPDAAADEQS 2589 + V LT ++G + R AD W+ +A T A P A A + Sbjct: 2594 DIVAVHVHLTPSRSEGAG------FTATLSTRAADVWTTHA--TASLAPIAPSALA--RR 2643 Query: 2590 DPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAV----GDILVGAE 2645 P + + + L E+F ++ WGP W WL V G + A Sbjct: 2644 VPPEALSRSGDPGVVGHLIESFESFQIGWGPQWR------WLRHATHVRARTGLGYLEAP 2697 Query: 2646 LAEQLGSEPMHPVLMD----LCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPR 2701 P+ LMD + + +G PL + L Sbjct: 2698 AGVPTDDAPLPGGLMDNAFAVVSATSPPEEAARAREAEGTASKAPPLPFSIERLV----- 2752 Query: 2702 RFYCRAR---WHRSAL-DSETQVFELEFVDL------GGRALGGIREFT---------VK 2742 +Y RA W L D+ T+ + D+ G + G RE T + Sbjct: 2753 -WYGRAETPCWAEFVLRDAGTRDADGYGGDITLWSREGASSEGASREGTPIATIEGLAFR 2811 Query: 2743 RAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDR 2802 RAP + L L R LY L W E P ++ G W + G D L G +P+D Sbjct: 2812 RAPADKFLPEL---PARNLYALTWPE--QPTASRSPRGRWALLGEDSLGVATGG-IPVDT 2865 Query: 2803 NTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAA 2862 D+ L + L RGA V C T L+S+VH A Sbjct: 2866 YADVDALRDAL----GRGAPCPDTVAVCLATAHGPSDTDE----------TELVSSVHTA 2911 Query: 2863 QGPSVKL-----------PGGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPAL 2910 ++ L L ++T+ VA +GE V D AALWG R+ E Sbjct: 2912 AARALALLNAWLSDERLASSTLVLLTQRAVATCAGEDVLDLASAALWGLVRSAQAENRDR 2971 Query: 2911 HCRLVDCDGSSEAVDXXXXXXXXP-GIQEPEIAVRQGKLLASRL 2953 LVD DGS + EP++A+R G+ LA RL Sbjct: 2972 AILLVDLDGSDASRRALPYAVGGALDDAEPQLALRDGRRLAPRL 3015 Score = 670 bits (1729), Expect = 0.0 Identities = 402/944 (42%), Positives = 532/944 (56%), Gaps = 27/944 (2%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAAS-AEEYWALLRDGREAISDVPKDRWDIEEFFDP 59 + SA P AI+G R PG + + LL +GR+A+ +PK+RWD + +DP Sbjct: 1593 VASARAPSPSDEPIAIVGLGLRLPGGVGDMDALFRLLEEGRDAVGPIPKERWDADAIYDP 1652 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 DP GK R A +D V FDA FFG+S RE + +DPQHR+L+ETAW+A+E +GI P Sbjct: 1653 DPEAKGKSYVRDAALIDRVDLFDAAFFGISPREAKQIDPQHRLLLETAWQALEDAGIVPA 1712 Query: 120 SLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVA 179 SL +++TGVFVG DY + T + EAY A+GT+ + AGR+++ LGLQGPA+A Sbjct: 1713 SLKDTSTGVFVGAGASDYAFLQG---TPSDAEAYAAMGTAFSFTAGRLAFTLGLQGPALA 1769 Query: 180 VDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFD 239 +DTACSSSLVA+H ACQ+LR ECDLALA G+ V +P I S LA DGR KTF Sbjct: 1770 IDTACSSSLVALHLACQSLRRGECDLALAAGSQVTASPDVFILLSRTRALAADGRSKTFS 1829 Query: 240 AAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI 299 A ADGY RGEG V+ ++RL DA G R+ AV+RG+A+N DGAS G+T PNG +QQ+V+ Sbjct: 1830 AHADGYGRGEGVVVLALERLRDAEARGHRVLAVVRGTAVNHDGASSGITAPNGTSQQKVL 1889 Query: 300 ADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGH 359 AL AGL PADV +E HGTGT+LGDPIE QA V G GRAPE PLL+G+ KTNIGH Sbjct: 1890 RAALGDAGLAPADVDVVECHGTGTALGDPIEVQALAAVYGEGRAPERPLLLGAVKTNIGH 1949 Query: 360 LEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGK--PR 417 LE +++ TLP +PHI W LP+ VV T PW+R + PR Sbjct: 1950 LEAASGLAGVAKIVAAMQHATLPATRGTTPLNPHIHWASLPVSVVGATRPWRRRDEETPR 2009 Query: 418 IAGVSSFGFAGTNAHVILEEAP--AVGTPATTEPVED---PRRYSVLP--LSARTPEALV 470 AGVS+FG +GTNAHVI+EEAP P T D PR +P LSA+T AL Sbjct: 2010 RAGVSAFGLSGTNAHVIVEEAPLARAAKPCATATGADGAAPRDGGPVPVLLSAKTEAALR 2069 Query: 471 RLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAP 530 A L AH A LADV+ + T R+H E RAA+V R++ + L A+A+ R AP Sbjct: 2070 AQAERLGAHLDAHAGAALADVAASLATTRSHFEHRAAIVAGDRDALRDALAAVAEGRSAP 2129 Query: 531 GLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDV 590 ++ G + K A LFTGQG Q M R L+ VF + + LE PL DV Sbjct: 2130 RVLVGRAVAGGKLALLFTGQGGQRAAMGRGLYGAFSVFRDAFDAACSYLDRELEHPLRDV 2189 Query: 591 IFDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVA 650 +F D + L T Y Q +LFA+E+ L RL ++WG P V++GHS+G+ AA VA Sbjct: 2190 VF--APRGADLAALLDETLYTQTSLFALEVALFRLVEAWGVTPHVLLGHSIGELVAAHVA 2247 Query: 651 GVFDVEDGARLIAERGRLFGSLP-AGGRMAAVFTAPERAERLTDEYPSL----SVAAYNG 705 GV +ED L+A R RL +LP M AV D L S+AA N Sbjct: 2248 GVLSLEDACTLVAARARLMHALPRRDAAMVAVHACEREVLDALDAMAGLDGRASIAAVNA 2307 Query: 706 -ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREP 764 ++TV++G + + + A A G + L SHAFHS LDP+L+ F A+ + ++ P Sbjct: 2308 PSSTVVAGDREAVLAVAARFEALGRKTSRLRVSHAFHSHHLDPMLEAFRRVAEGVRFQPP 2367 Query: 765 QRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTA 824 + ++ N TG+ AYW RHAR V FA + L LE+GP VL A Sbjct: 2368 RIPIVSNVTGARASNDDLCSAAYWVRHARGTVRFADGLEALRADGVSTFLELGPHAVLCA 2427 Query: 825 TALAAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLP 883 A L +LR D +T A+ A +A GH D+ AF P +A ++ LP Sbjct: 2428 LGHETLGSEAVA--FLPALRDGRDDVDTLTAALGALHARGHHVDWDAFFAPFNAGRVTLP 2485 Query: 884 TYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRL-LEDG 926 TY F+ +FW +A + ++ A+A S + RL L DG Sbjct: 2486 TYAFQRERFWLDMPKA--KSSRVAAADSAGRYPLAGTRLDLPDG 2527 Score = 647 bits (1670), Expect = 0.0 Identities = 402/932 (43%), Positives = 520/932 (55%), Gaps = 29/932 (3%) Query: 1533 DYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAI 1591 DYL + L L Q + + ++ +PIA+VA+SCRFP GA PE W+LL GG DA+ Sbjct: 13 DYL--KQLTLDLQRSQTRLHAAESKAYEPIAIVAMSCRFPGGARSPEDLWQLLEGGRDAV 70 Query: 1592 REVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRL 1650 P R W ++ DP D GKT FFG+SPREA+ ++PQQRL Sbjct: 71 SGFPASRGWSVEPRVDPRADVTGKTPALEGGFLEGAELFDAAFFGVSPREALEMDPQQRL 130 Query: 1651 MLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYA-HLLSAESIDKIEPHFITGNALNA 1709 +LET WE +ERA P+ L+GS+TGVF GV N YA H L + + ++ + Sbjct: 131 LLETTWEAIERAEIDPASLQGSQTGVFVGVMYNNYASHHLGGDG--DASGYVSFASSASV 188 Query: 1710 ISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVA 1769 SGR+A+ GF GP V VDTACSS+LVAVH ACQAL+SG+C LALAGGV V+ + A Sbjct: 189 ASGRIAYTFGFHGPTVTVDTACSSSLVAVHLACQALRSGECALALAGGVTVMATREAFDA 248 Query: 1770 ASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDG 1829 S A SP GRCK+F A A+G SEG G+++L+RLSDA R+G + AVI S+VNQDG Sbjct: 249 LSFAG--SPDGRCKSFSADANGAGWSEGAGMVLLERLSDAQRNGHPILAVIRGSAVNQDG 306 Query: 1830 ASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXX 1889 S GLT PNG AQ+R+I LA A L D+D +EAHGTGTPLGDPIE Sbjct: 307 KSQGLTAPNGPAQERVIRQALAAARLETHDIDAVEAHGTGTPLGDPIEANALLATYGLGR 366 Query: 1890 XXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVR 1949 PL +GS+K+N+GHT++A+G G+IK VL+L++G+LP++LH PSPH+ W A +R Sbjct: 367 PAERPLWLGSLKSNVGHTQAAAGVGGIIKTVLALRNGLLPRTLHAHAPSPHVDWAAGGLR 426 Query: 1950 VIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDD 2009 ++ + VPW NGRVRRA VSSFG +GTNAHV+VEEAP G D Sbjct: 427 LLADAVPWTRNGRVRRAAVSSFGLSGTNAHVIVEEAP-------RPDRDEASPAPSGRDQ 479 Query: 2010 SPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDS-- 2067 + VL LSA++ +AL A R L+ PG + DV + R+HF++RAA V S Sbjct: 480 ALPVL-LSAKTEDALRAQAARLHAHLAGDPGASLVDVAASLATTRAHFDHRAAFVARSRD 538 Query: 2068 VXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTV 2127 PA V A LFTGQGSQ P M R L+D P F + Sbjct: 539 ALLAALDAFARGAIDAPASVASVARRAPTKLALLFTGQGSQRPAMGRGLYDAFPAFRDAL 598 Query: 2128 RQCAEAVADMLPRPLLDVLFAT-DRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPD 2186 A L RPLLDVLFA E A LL T F QPALFA+E+ L RL ++ + PD Sbjct: 599 DAVASHFDRELDRPLLDVLFAPGGSELAALLDETLFTQPALFALEVALFRLVEACGLRPD 658 Query: 2187 VVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSL-PEGGRMVAVFADAEHVEQVAG 2245 +LGHS+G+ AA VAGV SL+D L+A R R+ +L P MVA+ A V V Sbjct: 659 ALLGHSIGELVAAHVAGVLSLEDACTLVAARARLMHALPPRDAAMVALNASEREVLDVLS 718 Query: 2246 EFPR-VSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDX 2303 P V + A NGP + V+SG + + + F+ G + + L SHAFHS +DP+L+ Sbjct: 719 AHPTGVGIAAVNGPASVVVSGDEDAVLAVAASFQARGRKTSRLRVSHAFHSHHMDPLLEA 778 Query: 2304 XXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCS 2363 P +P+V N TGA YW RH R V+FA+ V+ + A G S Sbjct: 779 FRRVAEGLTFHPPRIPIVSNVTGARAEEGELTSPDYWVRHVRGAVRFADGVQALRADGVS 838 Query: 2364 VLMEIGPQPVLTGAAVQVWPEHMAAPRAVA---SLRKGVADRRQIADALASAYVGGHRPD 2420 +E+GP VL E P A +LR AD A AL + Y G D Sbjct: 839 SFLELGPHGVLCALGSAALQEDRPPPEGAAFVPALRAERADDDAFAAALGALYTRGLTLD 898 Query: 2421 FAAVHR--QPRRPVELPTYPFQRRRFWPKASS 2450 + A+ PRR V LPTY FQR RFW +A+S Sbjct: 899 WRALFAPFAPRR-VPLPTYAFQRDRFWLEAAS 929 Score = 158 bits (399), Expect = 2e-35 Identities = 120/359 (33%), Positives = 156/359 (43%), Gaps = 15/359 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA+ GA +VLTSRR A+ R+ A DV Sbjct: 1222 LVTGGTGALGAHVARWLAKSGAEHLVLTSRRGRSAPGAEALQAELTALGARVTIAACDVA 1281 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D LL + A+ PL + H G L A + + +A KA GA + Sbjct: 1282 DRDAFGALLRDLEAQGSPLRAVVHAGGAAQGTPLDATSLDDLTRAIAGKAAGARNLDELT 1341 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 Q YA ANA LD L RRA+GL AT I +G W GGM Sbjct: 1342 GERALDAFVLFASGAGVWGGGHQGAYAAANAFLDALAESRRARGLTATSIAWGAWAGGGM 1401 Query: 3478 -ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA--RP 3534 A AA ++ +GL P+ P A+ ALA + + T+ +W R A L SA RP Sbjct: 1402 LAEDPAAEEHLRRRGLPPMAPELAIAALARALDHDDTNVTIADVDWARFAPSLASARSRP 1461 Query: 3535 PILDL--------VLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 + DL P AA G+ ELL L +P R + + +E L A Sbjct: 1462 LLHDLSEAKRALDARPEAAQGRDGEPELLATLRPLPAGDRLRHLVALVVKETALVLGHAD 1521 Query: 3587 PPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 R F D G DSLMA++LR RL G T+ AT FD+P LA +L L Sbjct: 1522 VARVEPRRGFFDSGLDSLMAVDLRVRLQRATG--VTLPATVTFDHPCPHDLAAHLCDAL 1578 Score = 147 bits (372), Expect = 2e-32 Identities = 179/655 (27%), Positives = 260/655 (39%), Gaps = 102/655 (15%) Query: 989 WILVGDDTAAVLE-------------FADALTAGGHRHQIVAL------PGSDADEAQLV 1029 W L+G+D+ V DAL G VA+ SD DE +LV Sbjct: 2846 WALLGEDSLGVATGGIPVDTYADVDALRDALGRGAPCPDTVAVCLATAHGPSDTDETELV 2905 Query: 1030 DTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVT 1089 ++ A+A L +++ D A +L Q + T Sbjct: 2906 SSVHTAAARALALLNAWLSDERLASSTLVLLTQRA----------------------VAT 2943 Query: 1090 RDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRD- 1148 G+ V D + + LWG R+A E L DL G+D L + D Sbjct: 2944 CAGEDVLDLAS-----AALWGLVRSAQAENRDRAILLVDLDGSDASRRALPYAVGGALDD 2998 Query: 1149 GEDQIALRGDAVYAPRLVRRTG------------------EPSDTPLPVREDRTYLVTGG 1190 E Q+ALR APRL R S TP + + T LVTGG Sbjct: 2999 AEPQLALRDGRRLAPRLARVAAPTAATSSAATPATPSAATSASATPRALDPEGTVLVTGG 3058 Query: 1191 LGAIGLEVAGYLAS-HGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHD 1249 G +G VA L HG H+VL SRR + V V AD AD Sbjct: 3059 TGTLGALVARRLVERHGVKHLVLLSRRGAEAPGASDLAAELQARGASVVVAAADAADRVA 3118 Query: 1250 VARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLR 1309 + R++ + + P L +VHAAG + LS + A + V KV A +L E Sbjct: 3119 LERVLLAIPHDRP-LTAVVHAAGTLDDGVLSSMTPARLSAVLRAKVDAAVNLDEQTR--H 3175 Query: 1310 TDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA--AGMA 1367 + L FV SS++ V G Q+ Y AANAFLD LA R RG+ AV++++G WA +G+ Sbjct: 3176 SPLRAFVLFSSLSGVLGSPAQSNYAAANAFLDALAHRRAARGLPAVALDWGYWAQTSGLT 3235 Query: 1368 DAESRA---RLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAF 1424 +A R+ + G+R L+ EALA +A +V + F + A Sbjct: 3236 KHLEQADLRRIARGGLRPLASDEALALFDLALAQDAPCLVP----AAFDADALRKSGDAL 3291 Query: 1425 LSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDAD 1484 + L + L +L +R ++ + +R VA V V + Sbjct: 3292 SALLRGLVTGPRARAQRASGAGDASALKLRLASLAPLERHRMLLDVVRADVATVLGVASP 3351 Query: 1485 -EIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLG 1543 +I +LG+DSLMA+ELR R+ G + TL+ +HP + D++L +++ L Sbjct: 3352 LDIEPGRPLQELGLDSLMAIELRNRLAAATGLRLSATLLFNHPTVGALTDHVLSKMIDLP 3411 Query: 1544 EQTNVRQASTVTARTDDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDR 1598 + AS G+P P S EL DAI +P DR Sbjct: 3412 SAGSPAPASA-------------------GSPAPASDAELR----DAIASIPLDR 3443 Score = 124 bits (310), Expect = 4e-25 Identities = 110/370 (29%), Positives = 163/370 (44%), Gaps = 19/370 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQL-GAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV 3356 L+TGG G +G A L + G +VL SRR + + + + AAD Sbjct: 3054 LVTGGTGTLGALVARRLVERHGVKHLVLLSRRGAEAPGASDLAAELQARGASVVVAAADA 3113 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D + +L I + P L + H AG LDD +LS+ P R L K A + Sbjct: 3114 ADRVALERVLLAIPHDRP-LTAVVHAAGTLDDGVLSSMTPARLSAVLRAKVDAAVNLDEQ 3172 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQ-G 3475 P Q+NYA ANA LD L +R A+GL A +++G W Q Sbjct: 3173 TRHSPLRAFVLFSSLSGVLGSPAQSNYAAANAFLDALAHRRAARGLPAVALDWGYWAQTS 3232 Query: 3476 GMAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSAR 3533 G+ +A I GL PL AL AL ++ V A A + G A Sbjct: 3233 GLTKHLEQADLRRIARGGLRPLASDEAL-ALFDLALAQDAPCLVPAAFDADALRKSGDAL 3291 Query: 3534 PPILDLVLPSAAGEA-----TGDSELLK-QLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 +L ++ A GD+ LK +L + +R + + ++ +V L +ASP Sbjct: 3292 SALLRGLVTGPRARAQRASGAGDASALKLRLASLAPLERHRMLLDVVRADVATVLGVASP 3351 Query: 3588 --PAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQ--- 3642 +LG DSLMAIELRNRL + G ++AT +F++PT+G L ++++ + Sbjct: 3352 LDIEPGRPLQELGLDSLMAIELRNRLAAATG--LRLSATLLFNHPTVGALTDHVLSKMID 3409 Query: 3643 LPDAEAPETA 3652 LP A +P A Sbjct: 3410 LPSAGSPAPA 3419 >tr|Q93H84|Q93H84_STRAW Tax_Id=33903 (pteA4)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 6145 Score = 1565 bits (4052), Expect = 0.0 Identities = 1005/2471 (40%), Positives = 1345/2471 (54%), Gaps = 117/2471 (4%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+ + R PG S E+ W L+ G + IS P+DR W++E +DPDP TPGK R Sbjct: 3048 AIVAMSCRLPGGVGSPEDLWQLVTSGGDVISGFPEDRGWNVEALYDPDPGTPGKTYARDG 3107 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FG+S RE MDPQ R+L+E +W A E +GI P SL S TGVFVG+ Sbjct: 3108 GFLYDAGDFDAALFGISPREALAMDPQQRLLLEASWEAFERAGIDPASLKGSRTGVFVGM 3167 Query: 133 ATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 + Y G + PE +E ++ G++ + +GR++Y GL+GPAV VDTACSSSLVA+ Sbjct: 3168 S---YQGYGAGLPQVPEGVEGHLLTGSAASVVSGRVAYSFGLEGPAVTVDTACSSSLVAL 3224 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A Q+LR E +A+AGG NV+ PA + FS LAPDGRCK F A ADG EG Sbjct: 3225 HLAIQSLRNGESTMAVAGGVNVMAVPAAFVEFSRQRGLAPDGRCKAFGAGADGTGWAEGV 3284 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 GVV+V+RL DAVR+G I AV+RGSA+NQDGAS GLT PNG AQQRVI AL AGL A Sbjct: 3285 GVVLVERLSDAVRNGHEILAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALASAGLTEA 3344 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT+LGDPIEAQA G R + PL +GS K+NIGH + Sbjct: 3345 DVDAVEAHGTGTALGDPIEAQALLATYGQERPEDRPLWLGSLKSNIGHAQAASGVAGVIK 3404 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 + + LP+ L+ + P+PH+ W + ++ E V W +PR A +SSFG +GTNA Sbjct: 3405 MVMAMRHGVLPRTLHADEPTPHVDWSAGAVRLLTEAVGWPDTNRPRRAAISSFGVSGTNA 3464 Query: 432 HVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADV 491 H I+E+AP V PA PVE LS ++ AL A + L DV Sbjct: 3465 HTIIEQAP-VAEPAAVAPVEVSSATVPWVLSGKSEAALRAQAERLLTLTADGAEPSLTDV 3523 Query: 492 SHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQG 551 + T RA LE RAA+V E L ALA PAPG V G + +A + +LF+GQG Sbjct: 3524 GFSLATTRAALEHRAAVVGADHGRIAEGLRALASGAPAPGAVLGRA-DAGQVGFLFSGQG 3582 Query: 552 SQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYA 611 SQ GM R+L++ PVFAE + + L++PL DV F + + E L T + Sbjct: 3583 SQRIGMGRQLYEAFPVFAEAYDEVCAHLDRHLDRPLRDVAFGENGHEDGEE--LNRTAFT 3640 Query: 612 QPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGS 671 QPALFA E+ + RL +SWG PD + GHSVG+ +AA VAG +ED A L+ R L + Sbjct: 3641 QPALFAHEVAVHRLLESWGVRPDYLAGHSVGEIAAAHVAGALALEDAAALVTARAALMQA 3700 Query: 672 LPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVA-DGV 729 LPAGG M AV T E LTD+ +AA NG +V+ +D +AVA A +G Sbjct: 3701 LPAGGAMIAVQATEDEVLPHLTDD---AGIAAINGPQSVVVSGTEDAVAAVADFFAREGR 3757 Query: 730 RCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWR 789 + L SHAFHS L+DP+L+DF L + P+ ++ N TG + T YW Sbjct: 3758 KISRLTVSHAFHSPLMDPVLEDFARVVGGLRFETPRTPVVSNLTGELIDAYT---ADYWV 3814 Query: 790 RHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTAD 849 RH R+ V FA +RTL ++ +E GP VL+A A +AS R + + Sbjct: 3815 RHVREAVRFADGIRTLGELGVTTFVETGPGAVLSAMAQGCLDGAVA----VASARSGSPE 3870 Query: 850 HRQITEAVAAAYAAGHLPDFRAF-RQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTAS 908 IT A+A + G D+RAF AR+ DLPTY F+H+++W ++ TA+ Sbjct: 3871 PEAITGALAQLHVHGVPVDWRAFFAGRGARRADLPTYAFQHQRYW------LETTAPTAA 3924 Query: 909 AGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDAR 968 AG+ T +E + LAA + E EQ VL +L+A QQR Sbjct: 3925 AGTDAVE-TGFWETVEREDAQSLAATL--ELPVEQLDAVLPRLSAWRRQQRRESAVEGWS 3981 Query: 969 YEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEF------ADALTAGGHRHQIVAL-PGS 1021 Y W LV +DT A F AD L A G R V + P + Sbjct: 3982 YRTGWKPLSGLRAHELRGNWLFLVTEDTEAFEAFEWTAAVADGLAARGARLVRVTVDPAA 4041 Query: 1022 DADEA--QLVDTLRAASA-GELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAAND 1078 D QL + +R + G + ++ I A P + V TL L +A D Sbjct: 4042 DRGALLRQLGEAVRESPLDGVISLLGIDERHHAGHPALSVGTVL--TLA----LVQALGD 4095 Query: 1079 AELRSPIWLVTRDGQRVTDTDTVVPE-QSCLWGFGRAAALELPHIWGGLADLSGADTEWP 1137 A + +P+W +TR D V Q+ +WG GR AALE WGGL DL DT Sbjct: 4096 AGIDAPLWALTRSAMSTGRADAVPSAAQNAVWGLGRVAALEHAPRWGGLIDLP--DTVDD 4153 Query: 1138 RLIARITS--PRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDR-TYLVTGGLGAI 1194 R+ R+ + + EDQ+A+R V+ RL + R T L+TGG GA+ Sbjct: 4154 RIAGRLAAVLAQSAEDQVAIRDRGVFGRRLSHTAARRNTRAAQGWSPRGTVLITGGTGAL 4213 Query: 1195 GLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLM 1254 G VA +LA GA H+VLTSRR P E V V DVAD +A L+ Sbjct: 4214 GGHVARWLAGAGAEHLVLTSRRGPDAPGAAGLVAELEATGVRVTVAACDVADREALAALL 4273 Query: 1255 TTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDF 1314 P+ +VH AG PL + V + K GA HL L +LD Sbjct: 4274 AE-----HPVNAVVHTAGVDHMEPLEAMTPGACADVLSAKAAGALHLDALLAG--QELDA 4326 Query: 1315 FVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG-MADAESR- 1372 FV SSIA VWG Q AY AANA LDGLA R R +G+ A +V +GPWA G MA+A+ Sbjct: 4327 FVLFSSIAGVWGSGHQAAYAAANALLDGLAERRRAQGLPATAVAWGPWAGGGMAEADGAD 4386 Query: 1373 ARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSEL-ES 1430 RL +RG+ + A A+AG+ + +G VA +DW RFLP + A L +L E+ Sbjct: 4387 ERLRRRGLIPMPAALAVAGLRRALDSGEATATVADVDWERFLPPFTVGRPSALLGDLPEA 4446 Query: 1431 ELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR-NAVAEVTRVDADEIRDE 1489 E L ++L + P ++ +L+ + +R +A A + +A E+ + Sbjct: 4447 ERILTADSTAGGPGTAAASPLADRLARMPETEQHALLVDLVRTHAAAVLGHNNAGEVEAD 4506 Query: 1490 AGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVR 1549 F DLG DSL AVELR +++ G +P TLV DHP A L E+ GL Sbjct: 4507 RAFKDLGFDSLTAVELRNKLKAETGLALPPTLVFDHPNAQALARQLRTELTGLTIAA-AP 4565 Query: 1550 QASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVPEDR-WDIDEFYDP 1607 +A+ A ++PIA+V ++CR+PG PE W L+A G DA+ + P DR WD+++ YDP Sbjct: 4566 EAAAAPAEDEEPIAIVGMACRYPGGVRSPEDLWHLVAAGGDAVGDFPADRGWDVEDIYDP 4625 Query: 1608 DPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPS 1667 DPD GKTY R P FFGISPREAV ++PQQRL+LET WE ERAG Sbjct: 4626 DPDARGKTYARRGGFLYEAGEFDPGFFGISPREAVAMDPQQRLLLETTWETFERAGIDAE 4685 Query: 1668 DLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAV 1727 +RGSRTGVF G +YA + +ID E F TGN+ + +SGR+A+ G EGPAV V Sbjct: 4686 SVRGSRTGVFVGSGYQDYA-ARAFNAIDDSEGFFGTGNSASIMSGRIAYTFGLEGPAVTV 4744 Query: 1728 DTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDA 1787 DTACSS+LVA+H A QAL++G+C +ALAGGV V+ +P V SR R L+P GRCK F A Sbjct: 4745 DTACSSSLVALHWAIQALRNGECSMALAGGVMVMSTPRAFVEFSRQRGLAPDGRCKAFGA 4804 Query: 1788 SADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIE 1847 ADG +EG G+L+++RLSDA R+G +V AV+ S+VNQDGAS+GLT PNG AQQR+I Sbjct: 4805 DADGTGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIR 4864 Query: 1848 ATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHT 1907 L AGL+ AD+D +EAHGTGT LGDPIE Q PL +GS+K+NIGHT Sbjct: 4865 QALTSAGLTAADIDAVEAHGTGTRLGDPIEAQALLATYGQERPAGQPLWLGSLKSNIGHT 4924 Query: 1908 ESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAG 1967 ++A+G AG+IK+V++++HGVLPQ+LH + P+PH+ W A VR++ E V W + R RRA Sbjct: 4925 QAAAGVAGVIKMVMAMRHGVLPQTLHVDEPTPHVDWSAGDVRLLTEAVAWPESERPRRAA 4984 Query: 1968 VSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL--ALSARSPEALV 2025 VSSFG +GTNAH ++E+APP +P +L LSA+S AL Sbjct: 4985 VSSFGVSGTNAHTIIEQAPP------------VPAEEATVTPAPALLPWVLSAKSSAALR 5032 Query: 2026 ELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPA 2085 + ARR ++ G+ +ADV + RS +RAA++ +S Sbjct: 5033 DQARRLLAFVE--DGMSLADVGFSLATTRSALRHRAAVIGESGDGFRRGLGSLAAGMPSP 5090 Query: 2086 GVVRGEHVHRP--TTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAEAVADMLPRPL 2142 GVV+G RP +LF+GQGSQ GM REL++ PVFA + CA A Sbjct: 5091 GVVQG----RPGGKVGFLFSGQGSQRIGMGRELYEAFPVFADAYDEVCARLEAP------ 5140 Query: 2143 LDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVA 2202 +DV A+ L T AQPALFAVE+ L RL +SW + PD V GHSVG+ AA VA Sbjct: 5141 VDV-------DAETLHRTGCAQPALFAVEVALFRLLESWGVRPDYVAGHSVGEIAAVHVA 5193 Query: 2203 GVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-NTV 2261 GV SLDD +L++ R + +LP GG MVAV A + V + V + A NGP + V Sbjct: 5194 GVLSLDDAVKLVSARAALMQALPAGGAMVAVQATEDEV--LPHLTDGVGMAAINGPRSVV 5251 Query: 2262 LSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLV 2321 +SG + + EI E F +G + + L SHAFHS L+DP+L+ P +P+V Sbjct: 5252 VSGAEDAVLEIAEVFTRQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFHQPQVPVV 5311 Query: 2322 CNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQV 2381 N TG + P +YW RH R+ V+FA+ + T+ LG + +EIGP VL+G Sbjct: 5312 SNLTGRL---AEPYSPEYWVRHVREAVRFADGIETLGELGVTTFVEIGPGGVLSGMVQDC 5368 Query: 2382 WPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQR 2441 E + P LR +++ + ALA + G D+ R+ +LPTY FQ Sbjct: 5369 VDEAVTVP----VLRGDRPEQQAVVTALAHLHTHGMSVDWNVFFAGARK-ADLPTYAFQH 5423 Query: 2442 RRFWPKASSIA 2452 +W A IA Sbjct: 5424 EPYWVDAPQIA 5434 Score = 1550 bits (4012), Expect = 0.0 Identities = 1004/2504 (40%), Positives = 1332/2504 (53%), Gaps = 139/2504 (5%) Query: 11 TPSFAIIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVV 68 T AI+G A R+PG AS EE W L+ G + +S P DR WD++ +DP+P G+ Sbjct: 18 TEPIAIVGMACRYPGGVASPEELWQLVASGGDGVSGFPTDRGWDLDTIYDPEPGRTGRTY 77 Query: 69 TRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGV 128 R GF+ D FD FFG+S RE +MDPQ R+L++T+W A+E +GI P + + GV Sbjct: 78 VREGGFLYDAGEFDPAFFGISPREALVMDPQQRLLLQTSWEALERAGIDPVTARGTRAGV 137 Query: 129 FVGL--ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSS 186 FVG H YL D + EA++ + A +GRISY LGL+GPAV VDTACSS Sbjct: 138 FVGTNGQDHAYLQRQGDS----DSEAHLVTANTAAVVSGRISYALGLEGPAVTVDTACSS 193 Query: 187 SLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYV 246 SLVA+H A QALR EC LALAGG V+ TP T I FS L+PDGRC+ F + ADG Sbjct: 194 SLVALHLAAQALRRGECSLALAGGVTVMATPNTFIAFSAQRGLSPDGRCRAFSSTADGTG 253 Query: 247 RGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRA 306 EG GV++++RL DA R G + AVIRGSA+NQDGAS GLT PNG +Q+RVI AL+ A Sbjct: 254 MSEGIGVLLLERLSDARRLGHEVLAVIRGSAVNQDGASNGLTAPNGPSQERVIRQALENA 313 Query: 307 GLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXX 366 L + V +EAHGT T+LGDPIEA+A G + + PL +GS K+NIGH + Sbjct: 314 RLTASQVDAVEAHGTATTLGDPIEAEALLATYGQEHSDDRPLWLGSIKSNIGHTQAAAGV 373 Query: 367 XXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGF 426 + N LP+ L+ + P+ + W ++++ E V W + PR A VSSFG Sbjct: 374 AGVIKMVMAIRNGVLPQTLDVDEPTAQVDWSAGGVKLLTEAVAWPESDHPRRAAVSSFGV 433 Query: 427 AGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLR--- 481 +GTNAH I+E+APA+ EP P LP LSA++ AL A +L Sbjct: 434 SGTNAHTIIEQAPALDREPAAEPAGAPAA-GALPWVLSAKSDAALRAQAERLLSFLEDGR 492 Query: 482 ---AHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESH 538 P AD+ + T R ++RAA+V S E E + ALA P+ +VR + Sbjct: 493 SGGTGPGRSPADIGFSLATTRTAWDRRAAVVGESLEELTEGVRALASGTPSAAVVRNAAR 552 Query: 539 EAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELD 598 KT +LF+GQGSQ GM REL+D PVFA + + LDV DAD Sbjct: 553 HGDKTGFLFSGQGSQRLGMGRELYDAFPVFAAAYDEI---------RAHLDVALDADA-- 601 Query: 599 GDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDG 658 L T QPALFAVE+ L RL +SWG PD V GHSVG+ +AA VAGV + D Sbjct: 602 ----EQLNQTGCTQPALFAVEVALFRLLESWGVRPDYVAGHSVGEIAAAHVAGVLSLGDA 657 Query: 659 ARLIAERGRLFGSLPAGGRMAAVFTAPERA-ERLTDEYPSLSVAAYNGANTVLSGPAKDL 717 ARL++ R L +LPAGG M AV A + LT + +AA NG +V+ A+D Sbjct: 658 ARLVSARAALMQALPAGGAMVAVQAAEDEVVPHLTH---GVGIAAINGPRSVVVSGAEDA 714 Query: 718 ESAVATLVAD-GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSA 776 A+ + G + L SHAFHS L+DP+L++F + L + EP+ ++ N TG Sbjct: 715 VLAIVEVFTQQGCKTSRLMVSHAFHSPLMDPVLEEFAEVVRGLTFSEPRIPVVANLTGRL 774 Query: 777 LGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATT 836 T YW RH R+ V FA + TL ++ +EIGP VL+A + D T Sbjct: 775 AEAYTP---EYWVRHVREAVRFADGIETLGELGVTTFVEIGPGGVLSALVQGCFDD-GTD 830 Query: 837 PQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSD 896 + SLR + + A+A + +G D+ AF P AR++DLPTY F+ +++W Sbjct: 831 IVTVPSLRADRPEPYALVTALAELHVSGAELDWHAFF-PGARRVDLPTYAFQQQRYWLEA 889 Query: 897 NRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHN 956 R+ +TA+ +V +V ED Q ++ E +D V+ KL+A Sbjct: 890 -----REAETATVDAVDAEFWASVES-EDAQSLAATLGLNPEELDV----VVPKLSAWRR 939 Query: 957 QQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILV---GDDTAAVLEFADALTAGGHRH 1013 ++R V RY++ W W+ GD+ A + A AG H Sbjct: 940 RRREQSVVDGRRYQLAWQPLNGLSAGDLSGSTWLFAAPEGDEWAGTVRTA---LAGRGAH 996 Query: 1014 QIVALPGSDADEAQLVDTLR--AASAGELY-VVHIAAGDGAAAPMRDLLRVQHRTLGGLR 1070 I G+DAD A L D L A AG L V+ + A D A+P L + Sbjct: 997 LIPLTVGADADRASLTDELTRVAGEAGSLDGVLSLLATDEIASPEHPALS---QGFAQSV 1053 Query: 1071 RLFRAANDAELRSPIWLVTRDGQRV--TDTDTVVPEQSCLWGFGRAAALELPHIWGGLAD 1128 L +A DA + +P+W TR +D + Q+ +WG GRA ALE WGGL D Sbjct: 1054 ALAQALGDAGVDAPLWCATRGAAATGRSDDAPLSAVQNQVWGLGRALALEHARRWGGLID 1113 Query: 1129 LSGADTEWP--RLIARITSPRDG----EDQIALRGDAVYAPRLVRRTGEPSDTPLPVRED 1182 L A E R+ A ++ D EDQ+A+R V+ RL S P Sbjct: 1114 LPAAVDERAAGRIAAVLSQGADAADGQEDQVAVRATGVFTARLAHAR---SGVGRPWSPR 1170 Query: 1183 RTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITA 1242 T L+TGG GA+G VA +LA GA H+VLTSRR E+ V + Sbjct: 1171 GTVLITGGTGALGGHVARWLAGAGAEHLVLTSRRGADAPGATALKAELEELGARVTLAVC 1230 Query: 1243 DVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLS 1302 DVAD +A L+ + HAAG P L A+ R A K GA HL Sbjct: 1231 DVADRDALAALLAEHT-----FTSVFHAAGVEQFAPFDELTPADFARTMAAKAHGAAHLD 1285 Query: 1303 EALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW 1362 E L D +LD FV SSIA VWG QTAY A NAFLDGLA R R RG+TA ++ +GPW Sbjct: 1286 ELLGD--RELDAFVLFSSIAGVWGSGLQTAYAAGNAFLDGLAARRRARGLTATAIAWGPW 1343 Query: 1363 A-AGMADAESRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAG 1420 A GM A L +RGV TL A A+ + + VVA IDW RF+ + Sbjct: 1344 ADGGMVTDADEAHLRRRGVVTLPAALAVTAVQRALDCDDTAVVVADIDWERFIGPFTFGR 1403 Query: 1421 RRAFLSELES--ELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEV 1478 A LSEL L +L P +R + + +R VA V Sbjct: 1404 PSALLSELPEVRRAGAVTAAVTAAPADVGATPLAARLAGLPEAERTHTLIDLVRAHVAAV 1463 Query: 1479 T-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLV 1537 A E+ + F LG DSL AVELR ++ G + TLV D+P + A +L Sbjct: 1464 LGHSSAAEVEPDRAFKALGFDSLTAVELRNKVNTATGLALSPTLVFDYPNATALARFLQS 1523 Query: 1538 EVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPE 1596 E+LG Q V Q A D+PIA+VA+SC PG D PE+ W+L+ G DAI E P Sbjct: 1524 ELLG--SQAVVEQEQHAAA-DDEPIAIVAMSCHLPGGVDSPEALWDLVTSGGDAISEFPS 1580 Query: 1597 DR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETV 1655 +R WD++ YDPDPD PGKTY R FFGISPREA+ ++PQQRLMLET Sbjct: 1581 NRGWDVEALYDPDPDRPGKTYARDGGFLYGATDFDAGFFGISPREALAMDPQQRLMLETS 1640 Query: 1656 WEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVA 1715 WE ERAG AP+ LRGSRTGVF G+A Y + + + +E H + G A + +SGRVA Sbjct: 1641 WEAFERAGIAPAQLRGSRTGVFVGMAYQGYGADVR-RTPEGVEGHRLVGGASSVVSGRVA 1699 Query: 1716 FALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARM 1775 + G EGPAV +DTACSS+LVA+H A Q+L++G+C +ALAGGV V+ P V SR R Sbjct: 1700 YTFGLEGPAVTIDTACSSSLVALHLAMQSLRNGECTMALAGGVTVMAGPSVFVEFSRQRG 1759 Query: 1776 LSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLT 1835 LSP GRC+ F A ADG +EG G+L+++RLSDA R+G +V AV+ S+VNQDGAS+GLT Sbjct: 1760 LSPDGRCRAFGADADGTGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLT 1819 Query: 1836 VPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPL 1895 PNG AQQR+I +LA AGL+ DVD +EAHGTGT LGDPIE Q PL Sbjct: 1820 APNGPAQQRVIHQSLASAGLAPRDVDAVEAHGTGTRLGDPIEAQALLATYGQGRDGDRPL 1879 Query: 1896 LMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPV 1955 +GS+K+NIGHT++A+G AG+IK+V++++HG+LP++LH + P+PH+ W A VR++ E V Sbjct: 1880 WLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGILPRTLHADEPTPHVDWSAGDVRLLTEAV 1939 Query: 1956 PWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVL- 2014 W + R RRA +SSFG +GTNAH ++E+AP T DS ++ Sbjct: 1940 DWPESDRPRRAAISSFGVSGTNAHTIIEQAPATAELPP-------------TPDSGALVP 1986 Query: 2015 -ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXX 2073 LS + AL A R D L A G +D+ + R FE RA L+ Sbjct: 1987 WVLSGKGEPALRAQAARLADHLDANDGWTASDI-GLSLASRETFEDRAVLLAQGSDKLRQ 2045 Query: 2074 XXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQ-CAE 2132 A V G +LF+GQGSQ GM REL++ PVFA + CA Sbjct: 2046 ALTALAAGQPAANVTLGRARSEGKVGFLFSGQGSQRIGMGRELYEAFPVFADAYDEVCAR 2105 Query: 2133 AVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHS 2192 A +DV A+ L T AQPALFAVE+ L RL +SW + PD V GHS Sbjct: 2106 LEAP------VDV-------DAETLHRTGCAQPALFAVEVALFRLLESWGVRPDYVAGHS 2152 Query: 2193 VGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSV 2252 VG+ AAA VAGV SLDD RL++ R + +LP GG MVAV A E V + V + Sbjct: 2153 VGEIAAAHVAGVLSLDDAVRLVSARAALMQALPVGGAMVAVQATEEEV--LPHLTDEVGI 2210 Query: 2253 GAYNGPNT-VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXX 2311 A NGP + VLSG GE + I E F +G + + L SHAFHS L+DP+L+ Sbjct: 2211 AAINGPRSMVLSGAGEAVTAIAEVFVGQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGL 2270 Query: 2312 XXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQ 2371 P +P+V N TG + P +YW RH R+ V+FA+ + T+ LG + +EIGP Sbjct: 2271 TFHQPQVPVVSNLTGRL---AEPYSPEYWVRHVREAVRFADGIETLGELGVTTFVEIGPG 2327 Query: 2372 PVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRP 2431 VL+G E + P LR +++ + ALA +V G PD+ A+ R Sbjct: 2328 GVLSGMVQDCVDEAVTVP----VLRGDRPEQQAVVTALAELHVHGVSPDWQALFPGAHR- 2382 Query: 2432 VELPTYPFQRRRFWPKASSIAVDGGTAASGILGSGKDLASGDTI 2475 V LPTY FQR RFW + +G AA+G D D++ Sbjct: 2383 VTLPTYAFQRERFW-----LDGEGDLAAAGTPTDAADSGFWDSV 2421 Score = 1516 bits (3925), Expect = 0.0 Identities = 965/2480 (38%), Positives = 1314/2480 (52%), Gaps = 111/2480 (4%) Query: 5 EHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPS 62 +H AI+ + PG S E W L+ G +AIS+ P +R WD+E +DPDP Sbjct: 1536 QHAAADDEPIAIVAMSCHLPGGVDSPEALWDLVTSGGDAISEFPSNRGWDVEALYDPDPD 1595 Query: 63 TPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLA 122 PGK R GF+ T FDA FFG+S RE MDPQ R+++ET+W A E +GIAP L Sbjct: 1596 RPGKTYARDGGFLYGATDFDAGFFGISPREALAMDPQQRLMLETSWEAFERAGIAPAQLR 1655 Query: 123 NSNTGVFVGLATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVD 181 S TGVFVG+A Y G +D PE +E + +G +++ +GR++Y GL+GPAV +D Sbjct: 1656 GSRTGVFVGMA---YQGYGADVRRTPEGVEGHRLVGGASSVVSGRVAYTFGLEGPAVTID 1712 Query: 182 TACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAA 241 TACSSSLVA+H A Q+LR EC +ALAGG V+ P+ + FS L+PDGRC+ F A Sbjct: 1713 TACSSSLVALHLAMQSLRNGECTMALAGGVTVMAGPSVFVEFSRQRGLSPDGRCRAFGAD 1772 Query: 242 ADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIAD 301 ADG EG G+++V+RL DA R+G ++ AV+RGSA+NQDGAS GLT PNG AQQRVI Sbjct: 1773 ADGTGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIHQ 1832 Query: 302 ALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLE 361 +L AGL P DV +EAHGTGT LGDPIEAQA G GR + PL +GS K+NIGH + Sbjct: 1833 SLASAGLAPRDVDAVEAHGTGTRLGDPIEAQALLATYGQGRDGDRPLWLGSLKSNIGHTQ 1892 Query: 362 XXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGV 421 + + LP+ L+ + P+PH+ W + ++ E V W + +PR A + Sbjct: 1893 AAAGVAGVIKMVMAMRHGILPRTLHADEPTPHVDWSAGDVRLLTEAVDWPESDRPRRAAI 1952 Query: 422 SSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLR 481 SSFG +GTNAH I+E+APA A P D LS + AL A D L Sbjct: 1953 SSFGVSGTNAHTIIEQAPAT---AELPPTPDSGALVPWVLSGKGEPALRAQAARLADHLD 2009 Query: 482 AHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAP 541 A+ +D+ + + R E RA L+ + + L ALA +PA + G + Sbjct: 2010 ANDGWTASDIGLSLAS-RETFEDRAVLLAQGSDKLRQALTALAAGQPAANVTLGRARSEG 2068 Query: 542 KTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDT 601 K +LF+GQGSQ GM REL++ PVFA+ + V LE P+ ++D +T Sbjct: 2069 KVGFLFSGQGSQRIGMGRELYEAFPVFADAY----DEVCARLEAPV--------DVDAET 2116 Query: 602 ESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARL 661 L T AQPALFAVE+ L RL +SWG PD V GHSVG+ +AA VAGV ++D RL Sbjct: 2117 ---LHRTGCAQPALFAVEVALFRLLESWGVRPDYVAGHSVGEIAAAHVAGVLSLDDAVRL 2173 Query: 662 IAERGRLFGSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGANT-VLSGPAKDLES 719 ++ R L +LP GG M AV T E LTDE + +AA NG + VLSG + + + Sbjct: 2174 VSARAALMQALPVGGAMVAVQATEEEVLPHLTDE---VGIAAINGPRSMVLSGAGEAVTA 2230 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 V G + L SHAFHS L+DP+L++F + L + +PQ ++ N TG Sbjct: 2231 IAEVFVGQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFHQPQVPVVSNLTGRL--- 2287 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 + YW RH R+ V FA + TL ++ +EIGP VL+ + T P V Sbjct: 2288 AEPYSPEYWVRHVREAVRFADGIETLGELGVTTFVEIGPGGVLSGMVQDCVDEAVTVP-V 2346 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 L RP + + + A+A + G PD++A P A ++ LPTY F+ +FW Sbjct: 2347 LRGDRP---EQQAVVTALAELHVHGVSPDWQALF-PGAHRVTLPTYAFQRERFW------ 2396 Query: 900 IDRDTQTASAGSVTPHRTQAV-RLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQ 958 +D + A+AG+ T +E E LAA + G + D +L +L+A Q+ Sbjct: 2397 LDGEGDLAAAGTPTDAADSGFWDSVEREDAESLAATL-GVSADASLGAILPRLSAWRRQR 2455 Query: 959 RSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVAL 1018 R V RY + W ++V ++ AL G + + Sbjct: 2456 REQSVVDGWRYRVTWKPLGALPQPGASGTWLLVVAGESEWTASVRTALDERG-LELVTLV 2514 Query: 1019 PGSDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAAND 1078 G D L L + +A + A+A L TL L +A D Sbjct: 2515 AGPGTDRGTLARELAGVGPVTGVLSLLAEDESASAGDPGLSHGLAATLC----LVQALGD 2570 Query: 1079 AELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLSGA-DTEW 1136 + P+W TR +D V P QS +WGFGRAAALE P WGGL DL D Sbjct: 2571 VGVDVPLWCATRGAVATGRSDRVDRPLQSQVWGFGRAAALEHPRRWGGLLDLPELLDART 2630 Query: 1137 PRLIARITSPRDGEDQIALRGDAVYAPRLVR--RTGEPSDTPLPVREDRTYLVTGGLGAI 1194 +A + + EDQ+A+R V RLVR R P+ P T L+TGG GA+ Sbjct: 2631 AARVAAVLG-QTAEDQVAVRASGVLGRRLVRAARATGPAQGWSP---RGTVLITGGTGAL 2686 Query: 1195 GLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLM 1254 G VA +LA GA H+VLTSRR P E+ V+ D AD + L+ Sbjct: 2687 GGHVARWLAGAGAEHLVLTSRRGPAAPGAAELVAELEELGAAATVVACDAADRDALRALL 2746 Query: 1255 TTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDF 1314 P+ +VHAAG + D A A K GA HL E L +LD Sbjct: 2747 AQ-----HPVNAVVHAAGVGDHVMIEDSDPAGFAGSVAAKAAGATHLDELLAG--QELDA 2799 Query: 1315 FVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA----AGMADAE 1370 FV SS A +WGG GQ AY AANA+LD LA R G TA++V++G WA AG+ D E Sbjct: 2800 FVMFSSGAGIWGGAGQGAYSAANAYLDALAEHRRAHGRTALAVSWGGWAEGGMAGVGDGE 2859 Query: 1371 SRARLEQRGVRTLSPAEALAGMADVVA-GPVQGVVAKIDWSRFLPLYQQAGRRAFLSELE 1429 L +RG+ + PA A++ + +A G VA DW RF+ + A S++ Sbjct: 2860 E--MLRRRGLPPMRPALAISALQQALADGETALTVADFDWERFIGPFTVTRPSALFSDVP 2917 Query: 1430 SELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDAD-EIRD 1488 L +LT P ++ + + +R A V D + Sbjct: 2918 E--AGRALEAPAPGGAEAGNALAAKLTGLPAAEQDRTLVDLVRTHAAAVLGHDGTAAVEP 2975 Query: 1489 EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNV 1548 F DLG DSL AVELR ++ G +P TLV D+P + A +L E+ LG + Sbjct: 2976 GRAFNDLGFDSLSAVELRNKLTADTGLKLPTTLVFDYPNATALARFLRAEL--LGSRGAA 3033 Query: 1549 RQASTVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYD 1606 RQ A D+PIA+VA+SCR P G PE W+L+ G D I PEDR W+++ YD Sbjct: 3034 RQEQRTAAVGDEPIAIVAMSCRLPGGVGSPEDLWQLVTSGGDVISGFPEDRGWNVEALYD 3093 Query: 1607 PDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP 1666 PDP TPGKTY R FGISPREA+ ++PQQRL+LE WE ERAG P Sbjct: 3094 PDPGTPGKTYARDGGFLYDAGDFDAALFGISPREALAMDPQQRLLLEASWEAFERAGIDP 3153 Query: 1667 SDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVA 1726 + L+GSRTGVF G++ Y L + + +E H +TG+A + +SGRVA++ G EGPAV Sbjct: 3154 ASLKGSRTGVFVGMSYQGYGAGL-PQVPEGVEGHLLTGSAASVVSGRVAYSFGLEGPAVT 3212 Query: 1727 VDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFD 1786 VDTACSS+LVA+H A Q+L++G+ +A+AGGVNV+ P V SR R L+P GRCK F Sbjct: 3213 VDTACSSSLVALHLAIQSLRNGESTMAVAGGVNVMAVPAAFVEFSRQRGLAPDGRCKAFG 3272 Query: 1787 ASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLI 1846 A ADG +EG GV++++RLSDAVR+G + AV+ S+VNQDGAS+GLT PNG AQQR+I Sbjct: 3273 AGADGTGWAEGVGVVLVERLSDAVRNGHEILAVVRGSAVNQDGASNGLTAPNGPAQQRVI 3332 Query: 1847 EATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGH 1906 LA AGL+ ADVD +EAHGTGT LGDPIE Q PL +GS+K+NIGH Sbjct: 3333 RQALASAGLTEADVDAVEAHGTGTALGDPIEAQALLATYGQERPEDRPLWLGSLKSNIGH 3392 Query: 1907 TESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRA 1966 ++ASG AG+IK+V++++HGVLP++LH + P+PH+ W A VR++ E V W R RRA Sbjct: 3393 AQAASGVAGVIKMVMAMRHGVLPRTLHADEPTPHVDWSAGAVRLLTEAVGWPDTNRPRRA 3452 Query: 1967 GVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVE 2026 +SSFG +GTNAH ++E+AP + LS +S AL Sbjct: 3453 AISSFGVSGTNAHTIIEQAP---------VAEPAAVAPVEVSSATVPWVLSGKSEAALRA 3503 Query: 2027 LARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAG 2086 A R + + DV + R+ E+RAA+V G Sbjct: 3504 QAERLLTLTADGAEPSLTDVGFSLATTRAALEHRAAVVGADHGRIAEGLRALASGAPAPG 3563 Query: 2087 VVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVL 2146 V G +LF+GQGSQ GM R+L++ PVFA+ + + L RPL DV Sbjct: 3564 AVLG-RADAGQVGFLFSGQGSQRIGMGRQLYEAFPVFAEAYDEVCAHLDRHLDRPLRDVA 3622 Query: 2147 FATD-RETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVF 2205 F + E + L T+F QPALFA E+ + RL +SW + PD + GHSVG+ AAA VAG Sbjct: 3623 FGENGHEDGEELNRTAFTQPALFAHEVAVHRLLESWGVRPDYLAGHSVGEIAAAHVAGAL 3682 Query: 2206 SLDDGARLMAERGRMFGSLPEGGRMVAVFADAE----HVEQVAGEFPRVSVGAYNGP-NT 2260 +L+D A L+ R + +LP GG M+AV A + H+ AG + A NGP + Sbjct: 3683 ALEDAAALVTARAALMQALPAGGAMIAVQATEDEVLPHLTDDAG------IAAINGPQSV 3736 Query: 2261 VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPL 2320 V+SG + + + + F EG + + L SHAFHS L+DPVL+ P P+ Sbjct: 3737 VVSGTEDAVAAVADFFAREGRKISRLTVSHAFHSPLMDPVLEDFARVVGGLRFETPRTPV 3796 Query: 2321 VCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ 2380 V N TG ++ T A YW RH R+ V+FA+ +RT+ LG + +E GP VL+ A Sbjct: 3797 VSNLTGELIDAYT---ADYWVRHVREAVRFADGIRTLGELGVTTFVETGPGAVLSAMAQG 3853 Query: 2381 VWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPF 2439 + AVAS R G + I ALA +V G D+ A + R +LPTY F Sbjct: 3854 C----LDGAVAVASARSGSPEPEAITGALAQLHVHGVPVDWRAFFAGRGARRADLPTYAF 3909 Query: 2440 QRRRFWPKASSIAVDGGTAA 2459 Q +R+W + ++ GT A Sbjct: 3910 QHQRYWLETTAPTAAAGTDA 3929 Score = 867 bits (2241), Expect = 0.0 Identities = 596/1571 (37%), Positives = 806/1571 (51%), Gaps = 86/1571 (5%) Query: 3 SAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPD 60 +A P E AI+G A R+PG S E+ W L+ G +A+ D P DR WD+E+ +DPD Sbjct: 4567 AAAAPAEDEEPIAIVGMACRYPGGVRSPEDLWHLVAAGGDAVGDFPADRGWDVEDIYDPD 4626 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 P GK RR GF+ + FD FFG+S RE MDPQ R+L+ET W E +GI S Sbjct: 4627 PDARGKTYARRGGFLYEAGEFDPGFFGISPREAVAMDPQQRLLLETTWETFERAGIDAES 4686 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 + S TGVFVG DY A + + + E + G S + +GRI+Y GL+GPAV V Sbjct: 4687 VRGSRTGVFVGSGYQDYAARAFNAID--DSEGFFGTGNSASIMSGRIAYTFGLEGPAVTV 4744 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVA+H A QALR EC +ALAGG V+ TP + FS LAPDGRCK F A Sbjct: 4745 DTACSSSLVALHWAIQALRNGECSMALAGGVMVMSTPRAFVEFSRQRGLAPDGRCKAFGA 4804 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 ADG EG G+++V+RL DA R+G ++ AV+RGSA+NQDGAS GLT PNG AQQRVI Sbjct: 4805 DADGTGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIR 4864 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 AL AGL AD+ +EAHGTGT LGDPIEAQA G R +PL +GS K+NIGH Sbjct: 4865 QALTSAGLTAADIDAVEAHGTGTRLGDPIEAQALLATYGQERPAGQPLWLGSLKSNIGHT 4924 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 + + + LP+ L+ + P+PH+ W + ++ E V W + +PR A Sbjct: 4925 QAAAGVAGVIKMVMAMRHGVLPQTLHVDEPTPHVDWSAGDVRLLTEAVAWPESERPRRAA 4984 Query: 421 VSSFGFAGTNAHVILEEAPAV-GTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYR 477 VSSFG +GTNAH I+E+AP V AT P ++LP LSA++ AL A Sbjct: 4985 VSSFGVSGTNAHTIIEQAPPVPAEEATVTPAP-----ALLPWVLSAKSSAALRDQARRLL 5039 Query: 478 DWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGES 537 ++ LADV + T R+ L RAA++ S + LG+LA P+PG+V+G Sbjct: 5040 AFVE--DGMSLADVGFSLATTRSALRHRAAVIGESGDGFRRGLGSLAAGMPSPGVVQGRP 5097 Query: 538 HEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADEL 597 K +LF+GQGSQ GM REL++ PVFA+ + V LE P+ ++ Sbjct: 5098 --GGKVGFLFSGQGSQRIGMGRELYEAFPVFADAY----DEVCARLEAPV--------DV 5143 Query: 598 DGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVED 657 D +T L T AQPALFAVE+ L RL +SWG PD V GHSVG+ +A VAGV ++D Sbjct: 5144 DAET---LHRTGCAQPALFAVEVALFRLLESWGVRPDYVAGHSVGEIAAVHVAGVLSLDD 5200 Query: 658 GARLIAERGRLFGSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKD 716 +L++ R L +LPAGG M AV T E LTD + +AA NG +V+ A+D Sbjct: 5201 AVKLVSARAALMQALPAGGAMVAVQATEDEVLPHLTD---GVGMAAINGPRSVVVSGAED 5257 Query: 717 LESAVATLVA-DGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGS 775 +A + G + L SHAFHS L+DP+L++F + L + +PQ ++ N TG Sbjct: 5258 AVLEIAEVFTRQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFHQPQVPVVSNLTGR 5317 Query: 776 ALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPAT 835 + YW RH R+ V FA + TL ++ +EIGP VL+ + T Sbjct: 5318 L---AEPYSPEYWVRHVREAVRFADGIETLGELGVTTFVEIGPGGVLSGMVQDCVDEAVT 5374 Query: 836 TPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFS 895 P VL RP + + + A+A + G D+ F ARK DLPTY F+H +W Sbjct: 5375 VP-VLRGDRP---EQQAVVTALAHLHTHGMSVDWNVFFA-GARKADLPTYAFQHEPYWVD 5429 Query: 896 DNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARH 955 Q A+A P + +E G ++ LA + G ++ VL +L++ Sbjct: 5430 A-------PQIAAAAEAEPVDAEFWETVERGDLQALAETL-GVGAGDKFGDVLPRLSSWR 5481 Query: 956 NQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXD-WIL------VGDDTAAVLEFADALTA 1008 Q++ RY W W++ +GDD V LT Sbjct: 5482 RQRKEQSTVDTWRYGESWKGIPDRVPEGPARIGLWLVPVSAAQLGDDW--VTACLRGLTE 5539 Query: 1009 GGHRHQIVALPGSDADEAQLVDTLRAASAGELY-VVHIAAGDGAAAPMRDLLRVQHRTLG 1067 G V + + E RAA + V+ + A D AAP L V L Sbjct: 5540 RGLAPLPVPVEPATGREDLAAQLTRAAGDETVAGVLSLLAVDCGAAPAAAALTVGV-ALS 5598 Query: 1068 GLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGL 1126 L L +A DA + +P+W VTR+ V+ D P QS +WG GR AALE WGGL Sbjct: 5599 VL--LVQALGDAGIGAPLWCVTRNAVGVSTADEATDPYQSQVWGLGRVAALEHAPRWGGL 5656 Query: 1127 ADLSGADTEWPRLIARITSP--RDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRT 1184 DL DT R+ R+ + + EDQ+A+R ++ RL R S+ R T Sbjct: 5657 IDLP--DTVDDRIAGRLAAVLGQSAEDQVAIRDRGLFVRRLSRLPAALSERSWSPRG--T 5712 Query: 1185 YLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADV 1244 L+TGG GA+G VA +LA GA H+VLTSRR P E+ V V DV Sbjct: 5713 VLITGGTGALGGHVARWLAGAGAEHLVLTSRRGPAAPGAAGLKAELEEAGVRVTVAACDV 5772 Query: 1245 ADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEA 1304 AD +A L+ P+ +VH AG L+ + A K GA HL E Sbjct: 5773 ADREALAVLLAE-----HPVNAVVHTAGTAEAGMLAETSLGDFAATVAAKALGAVHLHEL 5827 Query: 1305 LTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAA 1364 L D +LD FV SSI+ VWGG GQ AY AANAFLDGLA R RG+ A ++ +GPW Sbjct: 5828 LGD--QELDAFVLFSSISGVWGGGGQAAYSAANAFLDGLAQHRRARGLAATAIAWGPWGE 5885 Query: 1365 G--MADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQAGR 1421 G +ADA RL QRG+ L P A++ + ++G V VA +DW RF+ + Sbjct: 5886 GGMVADAGDEERLRQRGLSVLRPDRAISALHGALSGGDGTVTVADVDWERFVVPFTIGRP 5945 Query: 1422 RAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAEVTRV 1481 A LS+L E+ + T + ++++ L+ +A A + Sbjct: 5946 SALLSDL-PEVGDALAEKRTERAAEPSALKAKLSTLSEGERQRLLVDTVCAHAAAVLGHS 6004 Query: 1482 DADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLG 1541 + + + F DLG DSL AVELR + G +P TLV DHP A YL E Sbjct: 6005 GSAAVDPDLAFRDLGFDSLTAVELRNLLSADTGLTLPATLVFDHPTPEAIARYLRSE--- 6061 Query: 1542 LGEQTNVRQAS 1552 L ++T + S Sbjct: 6062 LADETGPEEVS 6072 Score = 659 bits (1700), Expect = 0.0 Identities = 394/909 (43%), Positives = 523/909 (57%), Gaps = 36/909 (3%) Query: 1549 RQASTVTARTDDPIAVVAVSCRFP-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYD 1606 RQ + A+ +PIA+V ++CR+P G PE W+L+A G D + P DR WD+D YD Sbjct: 8 RQLGELEAKDTEPIAIVGMACRYPGGVASPEELWQLVASGGDGVSGFPTDRGWDLDTIYD 67 Query: 1607 PDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP 1666 P+P G+TY R P FFGISPREA+ ++PQQRL+L+T WE LERAG P Sbjct: 68 PEPGRTGRTYVREGGFLYDAGEFDPAFFGISPREALVMDPQQRLLLQTSWEALERAGIDP 127 Query: 1667 SDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVA 1726 RG+R GVF G ++A+L D E H +T N +SGR+++ALG EGPAV Sbjct: 128 VTARGTRAGVFVGTNGQDHAYLQRQGDSDS-EAHLVTANTAAVVSGRISYALGLEGPAVT 186 Query: 1727 VDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFD 1786 VDTACSS+LVA+H A QAL+ G+C LALAGGV V+ +P T +A S R LSP GRC+ F Sbjct: 187 VDTACSSSLVALHLAAQALRRGECSLALAGGVTVMATPNTFIAFSAQRGLSPDGRCRAFS 246 Query: 1787 ASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLI 1846 ++ADG SEG GVL+L+RLSDA R G V AVI S+VNQDGAS+GLT PNG +Q+R+I Sbjct: 247 STADGTGMSEGIGVLLLERLSDARRLGHEVLAVIRGSAVNQDGASNGLTAPNGPSQERVI 306 Query: 1847 EATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGH 1906 L A L+ + VD +EAHGT T LGDPIE + PL +GS+K+NIGH Sbjct: 307 RQALENARLTASQVDAVEAHGTATTLGDPIEAEALLATYGQEHSDDRPLWLGSIKSNIGH 366 Query: 1907 TESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRA 1966 T++A+G AG+IK+V+++++GVLPQ+L + P+ + W A V+++ E V W + RRA Sbjct: 367 TQAAAGVAGVIKMVMAIRNGVLPQTLDVDEPTAQVDWSAGGVKLLTEAVAWPESDHPRRA 426 Query: 1967 GVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVE 2026 VSSFG +GTNAH ++E+AP P V LSA+S AL Sbjct: 427 AVSSFGVSGTNAHTIIEQAP-----ALDREPAAEPAGAPAAGALPWV--LSAKSDAALRA 479 Query: 2027 LARRYDDWL------SATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXX 2080 A R +L PG AD+ + R+ ++ RAA+V +S+ Sbjct: 480 QAERLLSFLEDGRSGGTGPGRSPADIGFSLATTRTAWDRRAAVVGESLEELTEGVRALAS 539 Query: 2081 XXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPR 2140 A VVR H T +LF+GQGSQ GM REL+D PVFA + R Sbjct: 540 GTPSAAVVRNAARHGDKTGFLFSGQGSQRLGMGRELYDAFPVFAAAYDEI---------R 590 Query: 2141 PLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAAC 2200 LDV D A+ L T QPALFAVE+ L RL +SW + PD V GHSVG+ AAA Sbjct: 591 AHLDVALDAD---AEQLNQTGCTQPALFAVEVALFRLLESWGVRPDYVAGHSVGEIAAAH 647 Query: 2201 VAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-N 2259 VAGV SL D ARL++ R + +LP GG MVAV A + V V V + A NGP + Sbjct: 648 VAGVLSLGDAARLVSARAALMQALPAGGAMVAVQAAEDEV--VPHLTHGVGIAAINGPRS 705 Query: 2260 TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLP 2319 V+SG + + IVE F +G + + L SHAFHS L+DPVL+ P +P Sbjct: 706 VVVSGAEDAVLAIVEVFTQQGCKTSRLMVSHAFHSPLMDPVLEEFAEVVRGLTFSEPRIP 765 Query: 2320 LVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAV 2379 +V N TG + TP +YW RH R+ V+FA+ + T+ LG + +EIGP VL+ A V Sbjct: 766 VVANLTGRLAEAYTP---EYWVRHVREAVRFADGIETLGELGVTTFVEIGPGGVLS-ALV 821 Query: 2380 QVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPF 2439 Q + V SLR + + ALA +V G D+ A RR V+LPTY F Sbjct: 822 QGCFDDGTDIVTVPSLRADRPEPYALVTALAELHVSGAELDWHAFFPGARR-VDLPTYAF 880 Query: 2440 QRRRFWPKA 2448 Q++R+W +A Sbjct: 881 QQQRYWLEA 889 Score = 173 bits (439), Expect = 4e-40 Identities = 123/363 (33%), Positives = 162/363 (44%), Gaps = 17/363 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G H A +LA GA +VLTSRR P + E R+ A DV Sbjct: 5714 LITGGTGALGGHVARWLAGAGAEHLVLTSRRGPAAPGAAGLKAELEEAGVRVTVAACDVA 5773 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A LLA P+ + H AG + +L+ + F T+A KA GA H Sbjct: 5774 DREALAVLLAE-----HPVNAVVHTAGTAEAGMLAETSLGDFAATVAAKALGAVHLHELL 5828 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQA Y+ ANA LDGL RRA+GL AT I +GPWG+GGM Sbjct: 5829 GDQELDAFVLFSSISGVWGGGGQAAYSAANAFLDGLAQHRRARGLAATAIAWGPWGEGGM 5888 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 + + +GL L P A+ AL ++ G G TV +W+R RP L Sbjct: 5889 VADAGDEERLRQRGLSVLRPDRAISALHGALSGGDGTVTVADVDWERFVVPFTIGRPSAL 5948 Query: 3538 --------DLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA 3589 D + A S L +L + +R + + + L + A Sbjct: 5949 LSDLPEVGDALAEKRTERAAEPSALKAKLSTLSEGERQRLLVDTVCAHAAAVLGHSGSAA 6008 Query: 3590 ASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAE 3647 F DLG DSL A+ELRN L + G T+ AT VFD+PT +A YL +L D Sbjct: 6009 VDPDLAFRDLGFDSLTAVELRNLLSADTG--LTLPATLVFDHPTPEAIARYLRSELADET 6066 Query: 3648 APE 3650 PE Sbjct: 6067 GPE 6069 Score = 172 bits (436), Expect = 9e-40 Identities = 128/371 (34%), Positives = 167/371 (45%), Gaps = 23/371 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G H A +LA GA +VLTSRR PD + E R+ A DV Sbjct: 4205 LITGGTGALGGHVARWLAGAGAEHLVLTSRRGPDAPGAAGLVAELEATGVRVTVAACDVA 4264 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A LLA P+ + H AGV L A P L+ KA GA H Sbjct: 4265 DREALAALLAE-----HPVNAVVHTAGVDHMEPLEAMTPGACADVLSAKAAGALHLDALL 4319 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 QA YA ANA+LDGL +RRAQGL AT + +GPW GGM Sbjct: 4320 AGQELDAFVLFSSIAGVWGSGHQAAYAAANALLDGLAERRRAQGLPATAVAWGPWAGGGM 4379 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 A ++ A + +GLIP+ + A+ L + +G ATV +W+R RP L Sbjct: 4380 AEADGADERLRRRGLIPMPAALAVAGLRRALDSGEATATVADVDWERFLPPFTVGRPSAL 4439 Query: 3538 DLVLPSAAGEATGD-----------SELLKQLMEIPIPQRAGFVTEFLQREVQNFL--RL 3584 LP A T D S L +L +P ++ + + ++ L Sbjct: 4440 LGDLPEAERILTADSTAGGPGTAAASPLADRLARMPETEQHALLVDLVRTHAAAVLGHNN 4499 Query: 3585 ASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLP 3644 A A F DLG DSL A+ELRN+L ++ G + T VFD+P LA L +L Sbjct: 4500 AGEVEADRAFKDLGFDSLTAVELRNKLKAETG--LALPPTLVFDHPNAQALARQLRTELT 4557 Query: 3645 D---AEAPETA 3652 A APE A Sbjct: 4558 GLTIAAAPEAA 4568 Score = 153 bits (386), Expect = 6e-34 Identities = 112/356 (31%), Positives = 157/356 (44%), Gaps = 17/356 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G H A +LA GA +VLTSRR P + E A D Sbjct: 2678 LITGGTGALGGHVARWLAGAGAEHLVLTSRRGPAAPGAAELVAELEELGAAATVVACDAA 2737 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D + LLA+ P+ + H AGV D ++ +P F ++A KA GA+H Sbjct: 2738 DRDALRALLAQ-----HPVNAVVHAAGVGDHVMIEDSDPAGFAGSVAAKAAGATHLDELL 2792 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQ Y+ ANA LD L RRA G A +++G W +GGM Sbjct: 2793 AGQELDAFVMFSSGAGIWGGAGQGAYSAANAYLDALAEHRRAHGRTALAVSWGGWAEGGM 2852 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 A + +GL P+ P+ A+ AL + +A+G TV +W+R RP L Sbjct: 2853 AGVGDGEEMLRRRGLPPMRPALAISALQQALADGETALTVADFDWERFIGPFTVTRPSAL 2912 Query: 3538 DLVLPSAA--------GEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA 3589 +P A G A + L +L +P ++ + + ++ L A Sbjct: 2913 FSDVPEAGRALEAPAPGGAEAGNALAAKLTGLPAAEQDRTLVDLVRTHAAAVLGHDGTAA 2972 Query: 3590 A--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 F DLG DSL A+ELRN+L + G K + T VFDYP LA +L +L Sbjct: 2973 VEPGRAFNDLGFDSLSAVELRNKLTADTGLK--LPTTLVFDYPNATALARFLRAEL 3026 Score = 152 bits (384), Expect = 1e-33 Identities = 116/365 (31%), Positives = 163/365 (44%), Gaps = 22/365 (6%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G H A +LA GA +VLTSRR D A+ E R+ DV Sbjct: 1174 LITGGTGALGGHVARWLAGAGAEHLVLTSRRGADAPGATALKAELEELGARVTLAVCDVA 1233 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A LLA + H AGV A P F T+A KA+GA+H Sbjct: 1234 DRDALAALLAE-----HTFTSVFHAAGVEQFAPFDELTPADFARTMAAKAHGAAHLDELL 1288 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 Q YA NA LDGL A+RRA+GL AT I +GPW GGM Sbjct: 1289 GDRELDAFVLFSSIAGVWGSGLQTAYAAGNAFLDGLAARRRARGLTATAIAWGPWADGGM 1348 Query: 3478 ASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPIL 3537 ++A A++ +G++ L + A+ A+ + V +W+R RP L Sbjct: 1349 V-TDADEAHLRRRGVVTLPAALAVTAVQRALDCDDTAVVVADIDWERFIGPFTFGRPSAL 1407 Query: 3538 DLVLP------------SAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFL--R 3583 LP +AA G + L +L +P +R + + ++ V L Sbjct: 1408 LSELPEVRRAGAVTAAVTAAPADVGATPLAARLAGLPEAERTHTLIDLVRAHVAAVLGHS 1467 Query: 3584 LASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A+ F LG DSL A+ELRN++++ G ++ T VFDYP LA +L +L Sbjct: 1468 SAAEVEPDRAFKALGFDSLTAVELRNKVNTATG--LALSPTLVFDYPNATALARFLQSEL 1525 Query: 3644 PDAEA 3648 ++A Sbjct: 1526 LGSQA 1530 Score = 41.6 bits (96), Expect = 2.4 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 3/105 (2%) Query: 2856 LSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPVD-PVQAALWGFGRTTINEEPALHCRL 2914 L V A V +P LW T VA + VD P+Q+ +WGFGR E P L Sbjct: 2562 LCLVQALGDVGVDVP--LWCATRGAVATGRSDRVDRPLQSQVWGFGRAAALEHPRRWGGL 2619 Query: 2915 VDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGKLLASRLLPWARS 2959 +D +A E ++AVR +L RL+ AR+ Sbjct: 2620 LDLPELLDARTAARVAAVLGQTAEDQVAVRASGVLGRRLVRAARA 2664 >tr|B6ZIR2|B6ZIR2_STRPT Tax_Id=58346 (pldAI)SubName: Full=Polyketide synthase;[Streptomyces platensis] Length = 6532 Score = 1565 bits (4052), Expect = 0.0 Identities = 1042/2730 (38%), Positives = 1424/2730 (52%), Gaps = 113/2730 (4%) Query: 2 VSAEHPIEPTPS----FAIIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDR-WDIEE 55 V H PT + AI+G R+PG AS E+ W L+ G +AIS P DR WD+E Sbjct: 1002 VEGAHDAAPTGAADEPIAIVGMGCRYPGGVASPEDLWRLVTSGGDAISGFPTDRGWDLEV 1061 Query: 56 FFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSG 115 +DPD PG TR GF+ + FDA FFG+S RE MDPQ R+L+ET+W AVE +G Sbjct: 1062 MYDPDHRRPGTSSTREGGFLYEAGDFDAGFFGISPREASAMDPQQRLLLETSWEAVERAG 1121 Query: 116 IAPTSLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQG 175 I P SL + GVFVG +Y G DE E ++ G + +GR++Y LGL+G Sbjct: 1122 IDPLSLHGTRAGVFVGAMAQEY-GPRLDEGA-DGYEGFLLTGGLTSVLSGRLAYSLGLEG 1179 Query: 176 PAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRC 235 PAV VDTACSSSLVA+H A QALR +C LALAGG V+ P + FS LAPDGRC Sbjct: 1180 PAVTVDTACSSSLVAVHMAAQALRQGQCSLALAGGVTVMSGPGIFLEFSRQSGLAPDGRC 1239 Query: 236 KTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQ 295 K F A ADG EG GV+V++RL DA R+G + AV+RGSAINQDGAS GLT PNG+AQ Sbjct: 1240 KAFAAGADGTGWAEGVGVLVLERLSDARRNGHPVLAVVRGSAINQDGASNGLTAPNGLAQ 1299 Query: 296 QRVIADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKT 355 +RVI +AL AGL PADV +EAHGTGT+LGDPIEAQA G GR + PL +GS K+ Sbjct: 1300 ERVIREALTDAGLSPADVDLVEAHGTGTTLGDPIEAQALIATYGQGRPADRPLRLGSLKS 1359 Query: 356 NIGHLEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGK 415 NIGH + + + T+P+ L+ + PSPH+ W + ++ E VPW + Sbjct: 1360 NIGHAQAAAGVGGVIKTVMAVRHATMPQTLHVDAPSPHVDWSSGQVRLLTEAVPWPESDH 1419 Query: 416 PRIAGVSSFGFAGTNAHVILEEAPAVGTPAT-------TEPVEDPRRYSVLPLSARTPEA 468 PR A VSSFG +GTNAHV++E+ PA + T E V P + LS ++PEA Sbjct: 1420 PRRAAVSSFGISGTNAHVVVEQPPAEVSAVTGPSPMAPDEAVPAPGQPVPWLLSGKSPEA 1479 Query: 469 LVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRP 528 + A R +L P A LAD+ + + R+ E R +V E LGA A Sbjct: 1480 VREQAARLRSYLADRPGAGLADIGWSLASTRSAFEHRTVVVAADHGQFREALGAAAAGSA 1539 Query: 529 APGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLL 588 +V G + KT ++F GQG+Q+ GMA EL D+ VFA + CA A+A + L Sbjct: 1540 DARVVEGVADIDGKTVFVFPGQGAQWAGMAGELLDSSEVFAARMADCARALAPFVGWSLQ 1599 Query: 589 DVIFDADELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAAC 648 DV+ A + PL QP L+AV + LA LW++ G EP VVGHS G+ +AAC Sbjct: 1600 DVVRQA-----EGAPPLDRVDVVQPVLWAVMVSLADLWRAHGVEPSAVVGHSQGEIAAAC 1654 Query: 649 VAGVFDVEDGARLIAERGRLFGSLPAG-GRMAAVFTAPERAER-LTDEYPSLSVAAYNGA 706 VAG +ED AR+++ R R + AG G M +V A E+ E L +S+A NG Sbjct: 1655 VAGGLTLEDAARVVSLRSRAIAEVLAGHGGMLSVTAAREQVEEWLLPWEGRISLATINGT 1714 Query: 707 -NTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQ 765 + V++G L A L +R L +A HSA ++ + + R + Sbjct: 1715 ESVVVAGDPDALAEFRAWLGNRQIRSRTLPVDYASHSAQVEAVHQRLLDDLAPIRPRTCR 1774 Query: 766 RILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTAT 825 L+ + TG L ++ +D YW ++ R+ VEFA + RTLAD R+ +E+ PVL Sbjct: 1775 TPLLSSVTGQWLDTAS-MDAEYWYQNLRRTVEFAAATRTLADGGHRIFIEVSSHPVLVGA 1833 Query: 826 ALAAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTY 885 V SLR R+ ++AA G PD+ + P + DLPTY Sbjct: 1834 IRETLEAVEVQAAVAGSLRRDDGGLRRFRLSLAALVTRGLAPDW-SMLCPGVSRTDLPTY 1892 Query: 886 PFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTL 945 PF+ ++W + A + +AV + G++ E+ +L D ++ E Sbjct: 1893 PFQRSRYWIT---AFSGSRSAGELNAADSRFWEAVDSEDPGRLAEVLSLDDDASL-EPVF 1948 Query: 946 RVLNKLAARHNQQRSTHVDPDARYEIRWD---XXXXXXXXXXXXXDWIL-VGDDTAAVLE 1001 L+ RH + RST D RY + W W++ V + A V + Sbjct: 1949 LALSSWRRRH-RVRSTL--DDWRYRVTWQPLPGAAVPLTAATLGGTWLVAVPHEDAYVSQ 2005 Query: 1002 FADALTAGGHRHQIVALPGSDADEAQLVDTLR--AASAGELY-VVHIAAGDGAAAPMRDL 1058 L G ++ L D L + +R A AGE+ V+ + A D P + Sbjct: 2006 VLRGL--GDRGATVITLRADDPRHGPLAERVREALAGAGEITGVLSLLALDERPHPEHPV 2063 Query: 1059 LRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTV-VPEQSCLWGFGRAAAL 1117 L + L L RA D ++R+P+W TR V +D + P Q+ +WG G AAL Sbjct: 2064 LPM---GLALNTALVRALVDKDVRAPLWCATRGAVSVGRSDRLGSPAQAMVWGLGLVAAL 2120 Query: 1118 ELPHIWGGLADLSGADTE--WPRLIARITSPR---------DG-----EDQIALRGDAVY 1161 E P WGGL DL E RL+ I+ R DG EDQ+A+R V+ Sbjct: 2121 EHPRHWGGLVDLPETVDERVLNRLVTVISGQRVHGQGAPGQDGENPGDEDQLAVRASGVF 2180 Query: 1162 APRLVRRTGEPSDTPLPVREDR------TYLVTGGLGAIGLEVAGYLASHGAGHVVLTSR 1215 A RL S P+ +R T LVTGG G G +VA +LA +GA H++LTSR Sbjct: 2181 ARRL-------SHAPVSGSRNREWTPRGTVLVTGGTGGAGTQVARWLARNGAEHLLLTSR 2233 Query: 1216 REPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIG 1275 R + V V DVAD +ARL+ V EL PL ++HAAG + Sbjct: 2234 RGRDAEGAAELAAELTEAGVRVTVAACDVADRDALARLLAGVPDEL-PLTAVIHAAGVVT 2292 Query: 1276 TTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGA 1335 T PL E+ V AGKV GA HL L D LD FV SS A VWG GQ AY A Sbjct: 2293 TAPLDSTGPEELAEVLAGKVAGAAHLDALLGD--RQLDAFVLFSSNAGVWGSGGQAAYAA 2350 Query: 1336 ANAFLDGLAWRLRERGVTAVSVNFGPW-AAGMADAES-RARLEQRGVRTLSPAEALAGMA 1393 ANA+LD LA + G TA SV +G W AGMA E + RL +RG+ + P A+ + Sbjct: 2351 ANAYLDALAQQRSSMGQTATSVAWGAWGGAGMAAEEGFKERLRRRGIIEMDPELAVTALV 2410 Query: 1394 DVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLV 1452 V +G VA +DW+RF+P + + +L L Sbjct: 2411 QAVESGEASIAVADVDWARFVPGFTSNRPSPLIGDLPEVRDALREADSRPAVDQGGSALA 2470 Query: 1453 EQLTKAPVQQRKSLITNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQ 1511 +L V +R+ ++ N +R VA V AD + F +LG DSL+AVE R R+ Sbjct: 2471 TRLAGLSVLERERVLLNLVRTEVASVLGHTTADMVDARRPFRELGFDSLIAVEFRGRLNA 2530 Query: 1512 GVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRF 1571 G +P ++ DHP ++ A +L E+ S TA D+PIA+VA+SCR+ Sbjct: 2531 ATGLRLPTSVAFDHPTPAELAGHLR-ELFAGSRGDTAMPVSVTTAGDDEPIAIVAMSCRY 2589 Query: 1572 P-GAPDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXX 1629 P G PE W L+A G DAI + P DR WDI+ YDPDP G +YTR Sbjct: 2590 PGGVRTPEDLWRLVAEGRDAITDFPTDRGWDIESLYDPDPGRSGTSYTRRGGFLDDAAAF 2649 Query: 1630 XPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLL 1689 P FF ISPREA+ ++PQQRL+LE WE LERA P+ L+GS+ GVF G A Y + Sbjct: 2650 DPAFFRISPREALAMDPQQRLLLEMTWETLERALIDPTTLKGSQAGVFIGTAHPGYGEGI 2709 Query: 1690 SAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGD 1749 ES +E + G + +GR+A+ G EGPA+ VDT CSS+LVA+H ACQ+L++G+ Sbjct: 2710 HHES-QGVEGQQLFGGSAAVAAGRIAYTFGLEGPAMTVDTMCSSSLVALHLACQSLRTGE 2768 Query: 1750 CDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDA 1809 +ALAGGV V+ P SR R LSP GRCK+F +ADG +EG GVL+L+RLSDA Sbjct: 2769 SSMALAGGVTVMARPTAFTEFSRHRGLSPDGRCKSFSDAADGTGWAEGAGVLLLERLSDA 2828 Query: 1810 VRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTG 1869 R+G V AVI S++NQDGAS+GLT PNG +QQR+I+ LA A LS ADV +EAHGTG Sbjct: 2829 RRNGHPVLAVIRGSAINQDGASNGLTAPNGPSQQRVIQQALANASLSPADVAAVEAHGTG 2888 Query: 1870 TPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLP 1929 T LGDPIE Q PL +GS+K+NIGH +SA+ G+IK+V +++HG+LP Sbjct: 2889 TTLGDPIEAQALIAAYGQDRPTDRPLRLGSLKSNIGHAQSAAAVGGVIKMVQAIRHGLLP 2948 Query: 1930 QSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQL 1989 ++LH E PS H+ W A V ++ E +PW N + RRAGVS+FG +GTNAH+++E+AP Sbjct: 2949 RTLHAEQPSRHVDWSAGSVELLTEAMPWPDNDQPRRAGVSAFGGSGTNAHMIIEQAPAPD 3008 Query: 1990 HXXXXXXXXXXXXXXXGTDDSPQVL---ALSARSPEALVELARRYDDWLSATPGLDIADV 2046 P + LSARS AL ARR + +A I D+ Sbjct: 3009 EPEHTDGTSRTSGESGAEQARPLPMVPWVLSARSDTALRAQARRLRAYAAAAEAGSICDI 3068 Query: 2047 CHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQG 2106 R+ + RA +V T G+VRG +A+LF+GQG Sbjct: 3069 GWALATTRATLDDRAVVVAAEREGFLTALDALAEDRTAPGLVRGAAGTGVRSAFLFSGQG 3128 Query: 2107 SQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATD-RETADLLQHTSFAQP 2165 SQ GM REL+DT VFA+ + + + L RPLL VLFA + + A +L T+F Q Sbjct: 3129 SQRLGMGRELYDTSLVFAEALDEVCAQLDGHLDRPLLRVLFAAEGSDDASMLDQTAFTQA 3188 Query: 2166 ALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLP 2225 ALFAVE+ L RL SW + PD ++GHSVG+ AAA V+GV SL D A L+ RGR+ +LP Sbjct: 3189 ALFAVEVALFRLVWSWGLRPDFLIGHSVGEVAAAHVSGVLSLADAATLVVARGRLMQALP 3248 Query: 2226 EGGRMVAVFADAEHVE-QVAGEFPRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRC 2283 GG MVA+ A E V +AG V V A NGP +TV+SG E + + + +G + Sbjct: 3249 SGGAMVALQAGEEEVRLSLAGLEDVVGVAALNGPASTVISGDEEAVLPVAAHWRAQGRKT 3308 Query: 2284 TWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRH 2343 L SHAFHS ++P+L P +P+V N TG A YW RH Sbjct: 3309 RRLKVSHAFHSPRMEPMLHRFHAVLKTLSFAEPAIPVVSNVTGRPAERTELCAADYWVRH 3368 Query: 2344 SRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRR 2403 R V+F + +R + A G S +E+GP L+ A V+ + LR+ D Sbjct: 3369 VRHTVRFHDGIRALEAEGVSAFLELGPDGTLS-AMVRDCLDTSRPVVTAPVLRRDRTDVS 3427 Query: 2404 QIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASSIAVDGGTAASG- 2461 ALA A+ G D+A++ R VELPTYPFQR FW + + + D TA Sbjct: 3428 AALTALAEAHGHGVPVDWASLFAGSTARAVELPTYPFQREHFWLDSVTGSSDMSTAGLAS 3487 Query: 2462 ----ILGSGKDLASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPA 2516 +LG+ +A D ++T LSV++ PWLADH I G+V++PG + +A+ A G A Sbjct: 3488 PDHPLLGAVTTVAGEDGLLFTGNLSVRTHPWLADHRITGSVLLPGTAFLELAVQA-GDQA 3546 Query: 2517 ---RLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGAD-WSLNAEG 2572 R++D+ P++LPE+ S VQ+ + D + +++S G + W LNA G Sbjct: 3547 GCGRVEDLTLLAPLVLPEEGSVRVQMKVGEPDATGRRTIEVYSSDQQAPGRERWVLNASG 3606 Query: 2573 TVDTAGSDPDAAADEQSDPVDEVIERLERMRPQDLF-ETFADLELAWGPTWSGSLKSLWL 2631 + AG +A + P + + P D F + A +GPT+ G L + W Sbjct: 3607 ML--AGEPVEAPPSLTTWPPEGAVP-----VPLDGFHDRLAARGYGYGPTFRG-LSAAWS 3658 Query: 2632 GDGEAVGDILVGAELAEQLGSEPMHPVLMD 2661 E + + + + +HP L+D Sbjct: 3659 RGDEIFAEAALPSGHRQDAARYGLHPALLD 3688 Score = 1206 bits (3119), Expect = 0.0 Identities = 943/2655 (35%), Positives = 1300/2655 (48%), Gaps = 172/2655 (6%) Query: 1082 RSPIWLVTRDGQRV-TDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI 1140 RS + ++TR V TD + + G R+A E P + L D+ + W L Sbjct: 3886 RSRLIVLTRGAVAVGTDEGVTDLVSASVRGLVRSAQAEHPGRFS-LVDIDDREESWAVLS 3944 Query: 1141 ARITSPRDGEDQIALRGDAVYAPRL----VRRTGEPSDTPLPVREDRTYLVTGGLGAIGL 1196 A S E Q+ALR + PRL V TG P + P D T L+TGG G +G Sbjct: 3945 AAAVSD---EPQLALRCGQMKVPRLGSVDVPTTGMP-EMPDVWGVDGTVLITGGTGVLGG 4000 Query: 1197 EVAGYL-ASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMT 1255 VA +L A HG ++L SRR P DV V D AD +A L+ Sbjct: 4001 LVARHLVAGHGVRRLLLCSRRGPDAPGAVELVAELTALGADVTVAACDAADRDALAALLD 4060 Query: 1256 TVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFF 1315 TV A PL G+VH AG I ++ L +D V KV A +L + L L F Sbjct: 4061 TVPAT-HPLTGVVHTAGVIDDATVTTLTPERIDAVLRPKVDAALNLHQLTAHL--GLTRF 4117 Query: 1316 VSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-----AGMADAE 1370 V SS A ++GG GQ Y AANAFLD LA R G+ A S+ +G WA G DA Sbjct: 4118 VLFSSAAGLFGGAGQGNYAAANAFLDALAQHRRANGLNAQSLAWGLWAEASGMTGHLDAA 4177 Query: 1371 SRARLEQRGVRTLSPAEALAGMADVVAGPVQG--VVAKIDWSRFLPLYQQAGRRAFLSEL 1428 AR+ + G+ + + LA + D + V A +D L+ +A + Sbjct: 4178 DLARVARSGLTAMPTGDGLA-LLDTAQRVDEATLVTAALDTRA---LHARAADGTLPALF 4233 Query: 1429 ESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQ-QRKSLITNYLRNAVAEVT-RVDADEI 1486 + + + Q V+ +R++ + + + VA V D I Sbjct: 4234 HALVPVPRRSATSPAAQAAGPDGLRQRLSGLVEGERRAALLDLVCGHVARVLGHADPSSI 4293 Query: 1487 RDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQT 1546 + F D G DSL AVELR + G +P TLV D+P + D+L E+LG E Sbjct: 4294 EETRPFKDTGFDSLTAVELRNVLHGATGLRLPATLVFDYPTPAALTDHLYDELLGSREDA 4353 Query: 1547 NVRQASTVTARTDDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEF 1604 + A A D+PIA+V ++CR+PG + PE W+L+A G DAI + P DR W+++ Sbjct: 4354 VL--APITRAAYDEPIAIVGMACRYPGGVESPEDLWQLVADGRDAISDFPADRGWNVESL 4411 Query: 1605 YDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGY 1664 Y PDPD PG +YTR PEFFGISPREA+ +PQQRL+LET WE E AG Sbjct: 4412 YHPDPDHPGTSYTRAGGFLHDAADFDPEFFGISPREALATDPQQRLLLETTWEAFEHAGV 4471 Query: 1665 APSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPA 1724 P+ LRGSRTGVF GV N+YA + + +E T +A + SGRV++ G EGPA Sbjct: 4472 GPASLRGSRTGVFVGVMYNDYASRIR-HIPESVEGGLTTNSAGSVASGRVSYTFGLEGPA 4530 Query: 1725 VAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKT 1784 V VDTACSS+LVA+H A QAL++G+C LALAGGV V+ +P T V SR R L+ GRCK Sbjct: 4531 VTVDTACSSSLVALHLAAQALRNGECTLALAGGVAVMSTPATFVEFSRQRGLAADGRCKA 4590 Query: 1785 FDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQR 1844 F +ADG EG GVL+++RLSDA R+G V AV+ S+VNQDGAS+GLT PNG +QQR Sbjct: 4591 FADAADGTGWGEGVGVLLVERLSDARRNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQR 4650 Query: 1845 LIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNI 1904 +I+ LA AGL+GADVD +EAHGTGT LGDPIE Q PL +GS+K+NI Sbjct: 4651 VIQQALANAGLAGADVDAVEAHGTGTRLGDPIEAQALIATYGQARSADRPLWLGSLKSNI 4710 Query: 1905 GHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVR 1964 GHT++A+G AG+IK+V ++QHG LP +LH + P+ + W V ++ E VPW + R R Sbjct: 4711 GHTQAAAGVAGVIKMVQAMQHGTLPPTLHIDQPTGQVDWATGAVELLTEAVPWPDSDRPR 4770 Query: 1965 RAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTD-DSPQVLALSARSPEA 2023 R VSSFG +GTNAHV++E P H P LSA++ +A Sbjct: 4771 RVAVSSFGVSGTNAHVIIEHTPHTPHTTRTSQSSQSPQAPQTVQAHRPVPWLLSAKTSQA 4830 Query: 2024 LVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXT 2083 L ARR L A P L ADV H+ RS RA + Sbjct: 4831 LAAQARRLSAHLRANPDLRSADVAHSLLTTRSVHAERAVFIAGDRDEALAALDALADGTP 4890 Query: 2084 PAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLL 2143 +V+G T ++F GQGSQ+ GMA EL D VFA+ + CA A+ + L Sbjct: 4891 APHLVQGLADVSGKTVFVFPGQGSQWVGMAVELLDGSEVFAEHMAACARALEPFVDWSLE 4950 Query: 2144 DVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAG 2203 DVL TD L+ QP L+AV + LA LWQ+ +EP VLGHS G+ AAACVAG Sbjct: 4951 DVLRQTDGTWP--LERVEVVQPVLWAVMVSLAGLWQAHGVEPAAVLGHSQGEIAAACVAG 5008 Query: 2204 VFSLDDGARLMAERGRMFGSLPEG-GRMVAVFADAEHVEQVAGEF-PRVSVGAYNGPNT- 2260 SL+DGAR++A R + G G M+++ A A + + + R+S+ NGP++ Sbjct: 5009 ALSLEDGARVVALRSQAIAETLAGHGGMLSIAAPATDIAPLIARWNERISIATVNGPHSV 5068 Query: 2261 VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPL 2320 V++G + LE + E G+R + +A H+ ++ + + ++P+ Sbjct: 5069 VVAGDPDALEALRGELETRGLRNRRIPVDYASHTPHVEAIRERLLADLAVIQPRAASIPV 5128 Query: 2321 VCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ 2380 + TGA L T +DA+YW R+ RQ V+F + RT+ +EI P PVLT Q Sbjct: 5129 LSTVTGAWL-DTTVMDAEYWYRNLRQTVEFEAATRTLLDQDHRYFVEISPHPVLTIGLQQ 5187 Query: 2381 VWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF--AAVHRQPRRPVELPTYP 2438 E A R +++LR+ R + +LA A+ G D+ A H +P R LPTYP Sbjct: 5188 TIEETTAPARTLSTLRRNEGTLRHLFTSLAQAHAHGLTIDWTPAFTHTEP-RTTPLPTYP 5246 Query: 2439 FQRRRFW-----PKASSIAVDG-GTAASGILGSGKDLA-SGDTIYTSRLSVKSQPWLADH 2491 FQ R+W PK+ +A G G+A +LG+ L SG ++T +LS++S PW ADH Sbjct: 5247 FQHERYWLEDGAPKSGDVASAGLGSADHPLLGAAVPLPDSGGFLFTGQLSLRSHPWFADH 5306 Query: 2492 VIYGTVVVPGATYAAMALAAVGT--PARLKDVFFYEPIILPEKASREVQLTLHPAD---- 2545 ++GTV++PG + +AL A G L+++ P++LPE +S ++QL ++ D Sbjct: 5307 AVHGTVLLPGTAFVELALQAGGRLGCGLLEELTLEAPLVLPENSSVQLQLVVNAPDAQDD 5366 Query: 2546 -GGSVLSFQIHSRPYGERGAD--WSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERM 2602 GG +F ++SRP +R AD W +A G V + G+ P+ P V +E Sbjct: 5367 SGGR--TFSVYSRPQ-DRTADAPWVRHATGVVRSGGA-PEPEGLTVWPPTGAVAVPVE-- 5420 Query: 2603 RPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVG-AELAEQLGSEP----MHP 2657 D ++ D +GP + G +++ W GD++ A LAE+ S+ +HP Sbjct: 5421 ---DFYQVLGDRGYDYGPAFRG-VRAAW-----RHGDVVYAEAALAEEQQSDAALFHLHP 5471 Query: 2658 VLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSE 2717 L+D + + EQ LP + VTL + S + Sbjct: 5472 ALLD--SALHGMGLMPSASAEQ----TRLPFAWRGVTL------HAVGASALRVSLRPAG 5519 Query: 2718 TQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATR-LLYTLGWHEVPPPPSAD 2776 E+ D GR + V+ +E L + DA R LY + W E+P P Sbjct: 5520 PDTVEVLLADGAGRPVASADALVVRPLRQEEL--AVWQDAYRDWLYRVDWPELPEVPLVA 5577 Query: 2777 DAVGTWL--------IAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVW 2828 A G W I G D A + G VPID DL L + + A F VV Sbjct: 5578 PA-GPWAVLGGNAGGILGTDGSAGLLAG-VPIDAYRDLAELRDRTGPSSA----FPAVVV 5631 Query: 2829 RCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEP 2888 G +L + + L +VT V+ G+ Sbjct: 5632 APVATG------TGAAPDAVREVTYQVLDMIQSWLADDRSASSTLLLVTRGAVSTGFGDD 5685 Query: 2889 -VDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEIAVRQGK 2947 VD QAA+WG R +E P L+D DG SE V G EP++A R+GK Sbjct: 5686 LVDLGQAAVWGLVRAAQSENPDRFV-LLDLDG-SEPVGPLPTAALLSG--EPQLAFREGK 5741 Query: 2948 LLASRL-LPWARSGHLTLPRGGD-FVLAPTERGAIDNLR-LTETDVPEP-DEGYVQVRVE 3003 +L +RL + +G L P G D + L T RG +DNL L V P EG V+V V Sbjct: 5742 VLTARLDRVSSDAGTLLPPAGPDPWRLDVTSRGTLDNLALLAAPQVSAPLAEGQVRVAVH 5801 Query: 3004 AAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFN 3063 AAGLNFRDVL LG+YPG+ G +G + AG V ++G GV L G RV G + G F Sbjct: 5802 AAGLNFRDVLVALGMYPGE-GSMGSEGAGVVLEVGPGVERLAPGDRVMGMLAGGFFGPVA 5860 Query: 3064 VPAQ-FLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGVGLAAIQ 3121 V Q + +PDG E A++P LT D L+ G +L+HAA+GGVG+AA Q Sbjct: 5861 VTDQRMVTKLPDGWSFTEGASVPIVFLTAYYGLVDLGGLRAGQSLLVHAATGGVGMAATQ 5920 Query: 3122 MAQQSGAEVFATASTFKRSTLRRLGV--KYVYDSRTTDFADQILADTNGAGVDVVLNSLT 3179 +A+ GAEVF TAS K LR +G+ +++ SR DF + A T G GVDVVLNSL Sbjct: 5921 LARHLGAEVFGTASPGKWEALRGMGLDEEHIASSRDLDFEKKFSAATGGRGVDVVLNSL- 5979 Query: 3180 SAGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDL 3239 + FV+A+L+ +GGRF E+ K DI E +A P + Y A D + PDRI+++ Sbjct: 5980 AREFVDASLRLLPRGGRFVEMGKTDIRDAEAVAAGHPGVVYR--AFDLLDAAGPDRIQEM 6037 Query: 3240 LTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLI 3299 L E+ G PLP + I A A R + QARHIGK+ D ++LI Sbjct: 6038 LAELLALFEAGVIEPLPLTTWDIRRAPEALRHLSQARHIGKM--VFTLPPAPDPDGTFLI 6095 Query: 3300 TGGLGAIGLHTAAYL-AQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGD 3358 TG GA+G A +L + G +++L SRR P + + A DV D Sbjct: 6096 TGVPGALGNLVARHLVTEGGIRNLLLVSRRGPAAPGAEGLATELAGLGATVTLAACDVAD 6155 Query: 3359 EAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXX 3418 +A LLA I AE PL G+ H AGVLDD ++++ ER PK A + Sbjct: 6156 RQALAGLLADIPAE-HPLTGVVHAAGVLDDGIVASLTRERLDAVYRPKVDAAWNLHELTK 6214 Query: 3419 XXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG-- 3476 GQ NYA ANA LD L R+AQGL A+ + +G W + G Sbjct: 6215 DSGLAAFVLFSSAAATLGSAGQGNYAAANAFLDALAQFRQAQGLAASSLGWGFWAESGEM 6274 Query: 3477 -----------MASSEAATANITAQGLIPLDP------SAALHALAEVIANG--SGQATV 3517 MA S A + QGL D ++ L E+ G +G TV Sbjct: 6275 TGHLGASDLARMARSGIAALTV-EQGLALFDSARSGVCASVLPVRLELTGPGARAGSGTV 6333 Query: 3518 LKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQRE 3577 A + G R P +V + G TG L ++L + R + E + Sbjct: 6334 -------PALMRGLVRAPARRVVETTTGGAVTG---LRQRLAPLSGADRDRALQELVCSH 6383 Query: 3578 VQNFL---RLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGG 3634 L R S PA + F +LG DSL A+ELRNRL+ G + AT VFD+PT Sbjct: 6384 AATVLGHSRSGSVPAQRA-FKELGFDSLTAVELRNRLNVATG--LRLPATLVFDHPTPLA 6440 Query: 3635 LAEYLVGQLPDAEAP 3649 +AE L +L E P Sbjct: 6441 MAEQLRKELFADEIP 6455 Score = 657 bits (1695), Expect = 0.0 Identities = 390/929 (41%), Positives = 526/929 (56%), Gaps = 26/929 (2%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G A R+PG S E+ W L+ DGR+AISD P DR W++E + PDP PG TR Sbjct: 4368 AIVGMACRYPGGVESPEDLWQLVADGRDAISDFPADRGWNVESLYHPDPDHPGTSYTRAG 4427 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FD FFG+S RE DPQ R+L+ET W A EH+G+ P SL S TGVFVG+ Sbjct: 4428 GFLHDAADFDPEFFGISPREALATDPQQRLLLETTWEAFEHAGVGPASLRGSRTGVFVGV 4487 Query: 133 ATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAI 191 +DY AS PE +E + ++ + A+GR+SY GL+GPAV VDTACSSSLVA+ Sbjct: 4488 MYNDY---ASRIRHIPESVEGGLTTNSAGSVASGRVSYTFGLEGPAVTVDTACSSSLVAL 4544 Query: 192 HQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGC 251 H A QALR EC LALAGG V+ TPAT + FS LA DGRCK F AADG GEG Sbjct: 4545 HLAAQALRNGECTLALAGGVAVMSTPATFVEFSRQRGLAADGRCKAFADAADGTGWGEGV 4604 Query: 252 GVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPA 311 GV++V+RL DA R+G + AV+ GSA+NQDGAS GLT PNG +QQRVI AL AGL A Sbjct: 4605 GVLLVERLSDARRNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIQQALANAGLAGA 4664 Query: 312 DVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXX 371 DV +EAHGTGT LGDPIEAQA G R+ + PL +GS K+NIGH + Sbjct: 4665 DVDAVEAHGTGTRLGDPIEAQALIATYGQARSADRPLWLGSLKSNIGHTQAAAGVAGVIK 4724 Query: 372 XXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNA 431 +++ TLP L+ + P+ + W +E++ E VPW + +PR VSSFG +GTNA Sbjct: 4725 MVQAMQHGTLPPTLHIDQPTGQVDWATGAVELLTEAVPWPDSDRPRRVAVSSFGVSGTNA 4784 Query: 432 HVILEEAP-AVGTPATTEPVEDPRRYSVLP--------LSARTPEALVRLAGEYRDWLRA 482 HVI+E P T T++ + P+ + LSA+T +AL A LRA Sbjct: 4785 HVIIEHTPHTPHTTRTSQSSQSPQAPQTVQAHRPVPWLLSAKTSQALAAQARRLSAHLRA 4844 Query: 483 HPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPK 542 +P R ADV+H+ T R+ +RA + R+ A+ L ALAD PAP LV+G + + K Sbjct: 4845 NPDLRSADVAHSLLTTRSVHAERAVFIAGDRDEALAALDALADGTPAPHLVQGLADVSGK 4904 Query: 543 TAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTE 602 T ++F GQGSQ+ GMA EL D VFAE + CA A+ ++ L DV+ D Sbjct: 4905 TVFVFPGQGSQWVGMAVELLDGSEVFAEHMAACARALEPFVDWSLEDVLRQT-----DGT 4959 Query: 603 SPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLI 662 PL QP L+AV + LA LWQ+ G EP V+GHS G+ +AACVAG +EDGAR++ Sbjct: 4960 WPLERVEVVQPVLWAVMVSLAGLWQAHGVEPAAVLGHSQGEIAAACVAGALSLEDGARVV 5019 Query: 663 AERGRLFGSLPA--GGRMAAVFTAPERAERLTDEYPSLSVAAYNGANT-VLSGPAKDLES 719 A R + A GG ++ A + A + +S+A NG ++ V++G LE+ Sbjct: 5020 ALRSQAIAETLAGHGGMLSIAAPATDIAPLIARWNERISIATVNGPHSVVVAGDPDALEA 5079 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 L G+R + +A H+ ++ I + + ++ R ++ TG+ L Sbjct: 5080 LRGELETRGLRNRRIPVDYASHTPHVEAIRERLLADLAVIQPRAASIPVLSTVTGAWLD- 5138 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 +T +D YW R+ RQ VEF + RTL D + R +EI P PVLT + + Sbjct: 5139 TTVMDAEYWYRNLRQTVEFEAATRTLLDQDHRYFVEISPHPVLTIGLQQTIEETTAPART 5198 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFR-AFRQPDARKLDLPTYPFEHRQFWFSDNR 898 L++LR R + ++A A+A G D+ AF + R LPTYPF+H ++W D Sbjct: 5199 LSTLRRNEGTLRHLFTSLAQAHAHGLTIDWTPAFTHTEPRTTPLPTYPFQHERYWLEDGA 5258 Query: 899 AIDRDTQTASAGSVT-PHRTQAVRLLEDG 926 D +A GS P AV L + G Sbjct: 5259 PKSGDVASAGLGSADHPLLGAAVPLPDSG 5287 Score = 655 bits (1690), Expect = 0.0 Identities = 395/972 (40%), Positives = 532/972 (54%), Gaps = 14/972 (1%) Query: 1484 DEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLG 1543 D + + F LG DS+M+VELR R+ G +P T++ +HP A +L E Sbjct: 943 DSVDPKLTFKQLGFDSVMSVELRNRLSSATGSSLPSTVLFNHPTPDRLARHLSAEA---S 999 Query: 1544 EQTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDI 1601 Q + T D+PIA+V + CR+PG PE W L+ G DAI P DR WD+ Sbjct: 1000 SQVEGAHDAAPTGAADEPIAIVGMGCRYPGGVASPEDLWRLVTSGGDAISGFPTDRGWDL 1059 Query: 1602 DEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLER 1661 + YDPD PG + TR FFGISPREA ++PQQRL+LET WE +ER Sbjct: 1060 EVMYDPDHRRPGTSSTREGGFLYEAGDFDAGFFGISPREASAMDPQQRLLLETSWEAVER 1119 Query: 1662 AGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFE 1721 AG P L G+R GVF G A EY L E D E +TG + +SGR+A++LG E Sbjct: 1120 AGIDPLSLHGTRAGVFVGAMAQEYGPRLD-EGADGYEGFLLTGGLTSVLSGRLAYSLGLE 1178 Query: 1722 GPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGR 1781 GPAV VDTACSS+LVAVH A QAL+ G C LALAGGV V+ P + SR L+P GR Sbjct: 1179 GPAVTVDTACSSSLVAVHMAAQALRQGQCSLALAGGVTVMSGPGIFLEFSRQSGLAPDGR 1238 Query: 1782 CKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGA 1841 CK F A ADG +EG GVLVL+RLSDA R+G V AV+ S++NQDGAS+GLT PNG A Sbjct: 1239 CKAFAAGADGTGWAEGVGVLVLERLSDARRNGHPVLAVVRGSAINQDGASNGLTAPNGLA 1298 Query: 1842 QQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVK 1901 Q+R+I L AGLS ADVD +EAHGTGT LGDPIE Q PL +GS+K Sbjct: 1299 QERVIREALTDAGLSPADVDLVEAHGTGTTLGDPIEAQALIATYGQGRPADRPLRLGSLK 1358 Query: 1902 TNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNG 1961 +NIGH ++A+G G+IK V++++H +PQ+LH + PSPH+ W + VR++ E VPW + Sbjct: 1359 SNIGHAQAAAGVGGVIKTVMAVRHATMPQTLHVDAPSPHVDWSSGQVRLLTEAVPWPESD 1418 Query: 1962 RVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSP 2021 RRA VSSFG +GTNAHV+VE+ P ++ P LS +SP Sbjct: 1419 HPRRAAVSSFGISGTNAHVVVEQPPAEVSAVTGPSPMAPDEAVP-APGQPVPWLLSGKSP 1477 Query: 2022 EALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXX 2081 EA+ E A R +L+ PG +AD+ + RS FE+R +V Sbjct: 1478 EAVREQAARLRSYLADRPGAGLADIGWSLASTRSAFEHRTVVVAADHGQFREALGAAAAG 1537 Query: 2082 XTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRP 2141 A VV G T ++F GQG+Q+ GMA EL D+ VFA + CA A+A + Sbjct: 1538 SADARVVEGVADIDGKTVFVFPGQGAQWAGMAGELLDSSEVFAARMADCARALAPFVGWS 1597 Query: 2142 LLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACV 2201 L DV+ E A L QP L+AV + LA LW++ +EP V+GHS G+ AAACV Sbjct: 1598 LQDVV--RQAEGAPPLDRVDVVQPVLWAVMVSLADLWRAHGVEPSAVVGHSQGEIAAACV 1655 Query: 2202 AGVFSLDDGARLMAERGRMFGSLPEG-GRMVAVFADAEHVEQVAGEFP-RVSVGAYNG-P 2258 AG +L+D AR+++ R R + G G M++V A E VE+ + R+S+ NG Sbjct: 1656 AGGLTLEDAARVVSLRSRAIAEVLAGHGGMLSVTAAREQVEEWLLPWEGRISLATINGTE 1715 Query: 2259 NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTL 2318 + V++G + L E + IR L +A HS ++ V Sbjct: 1716 SVVVAGDPDALAEFRAWLGNRQIRSRTLPVDYASHSAQVEAVHQRLLDDLAPIRPRTCRT 1775 Query: 2319 PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAA 2378 PL+ + TG L +DA+YW ++ R+ V+FA + RT+A G + +E+ PVL GA Sbjct: 1776 PLLSSVTGQWL-DTASMDAEYWYQNLRRTVEFAAATRTLADGGHRIFIEVSSHPVLVGAI 1834 Query: 2379 VQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYP 2438 + SLR+ R+ +LA+ G PD++ + R +LPTYP Sbjct: 1835 RETLEAVEVQAAVAGSLRRDDGGLRRFRLSLAALVTRGLAPDWSMLCPGVSR-TDLPTYP 1893 Query: 2439 FQRRRFWPKASS 2450 FQR R+W A S Sbjct: 1894 FQRSRYWITAFS 1905 Score = 598 bits (1543), Expect = e-168 Identities = 395/1045 (37%), Positives = 539/1045 (51%), Gaps = 50/1045 (4%) Query: 1559 DDPIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTR 1618 DD IA++ +SCR P A +P+ FWELL G I EVP RWD + +D + TPG TR Sbjct: 6 DDAIAIIGMSCRLPRAVNPQEFWELLRNGESGITEVPPQRWDANSLFDAERSTPGTMNTR 65 Query: 1619 XXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFT 1678 P FFGIS REAV ++PQQRL+LE WE LE A P LR + TGVF Sbjct: 66 WGGFIDGVDQFDPGFFGISSREAVAMDPQQRLVLELSWEALEDARIVPERLRHTATGVFV 125 Query: 1679 GVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAV 1738 G ++YA L+SA + + H +TG + I+ RV++ALG +GP++AVD+ SS+LV+V Sbjct: 126 GAIWDDYASLMSARGREAVTHHTVTGTHRSIIANRVSYALGLQGPSMAVDSGQSSSLVSV 185 Query: 1739 HQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGC 1798 H AC++L+ G+ LALAGGVN+ L P + + ++ LSP GRC TFD A+GYVR EG Sbjct: 186 HLACESLRRGESTLALAGGVNLNLVPESTIGMAKFGGLSPDGRCFTFDTRANGYVRGEGG 245 Query: 1799 GVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGA 1858 GV+VLK L+DA+ D D + VI S+VN DG+ LT PN AQ ++ RAG+ A Sbjct: 246 GVVVLKPLADAIADQDPIYCVIRGSAVNNDGSGENLTTPNSQAQAAVLREAYRRAGVDPA 305 Query: 1859 DVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIK 1918 V Y+E HGTGTP+GDPIE + PL +GS KTNIGH E+A+G AGL+K Sbjct: 306 QVQYVELHGTGTPVGDPIEAEALGAVIGAARPPGDPLWVGSAKTNIGHLEAAAGIAGLLK 365 Query: 1919 VVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNA 1978 VVLS+ H LP SL+F +P IP D+L +RV DE W + GR AGVS+FG GTNA Sbjct: 366 VVLSISHRELPASLNFATANPRIPLDSLNLRVGDELTSWPSAGRPMLAGVSAFGMGGTNA 425 Query: 1979 HVLVEEAPPQLHXXXXXXXXXXXXXXXGTDD-SPQVLALSARSPEALVELARRYDDWLSA 2037 H +VE++P TD P LS S A+ A R L Sbjct: 426 HAVVEQSPVAARQIPAPGGTP-------TDQGGPVPWLLSGGSVAAVRGQAARLLSHLEG 478 Query: 2038 TPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPT 2097 GL DV + RS F +RA +V D AGVV G Sbjct: 479 RSGLRAVDVGWSLATTRSVFPHRAVVVADD-GGYGQSLAALAAGSVDAGVVEGLADVSGK 537 Query: 2098 TAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLL 2157 T ++F GQGSQ+ GMA EL D VFA+ + CA A+ + L DVL D + L Sbjct: 538 TVFVFPGQGSQWVGMAVELLDGSEVFAEHMAACARALEPFVGWSLEDVLRQVDGTWS--L 595 Query: 2158 QHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAER 2217 QP L+AV + LA LWQ+ +EP VLGHS G+ AAACVAG SL+DGAR++A R Sbjct: 596 DRVDVVQPVLWAVMVSLAGLWQAHGVEPAAVLGHSQGEIAAACVAGALSLEDGARVVALR 655 Query: 2218 GRMFGSLPEG-GRMVAVFADAEHVEQVAGEFPR-VSVGAYNGPNT-VLSGPGEDLEEIVE 2274 R G G M+++ A A V + + R +++ NGP++ V++G + LE + Sbjct: 656 SRAIAEALAGHGGMLSIAAPATEVTALITPWGRQITIATVNGPHSVVVAGDPDALEALRG 715 Query: 2275 RFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTP 2334 E G+R + +A H+ ++ + + ++P++ TGA L T Sbjct: 716 ELETRGLRNRRIPVDYASHTPHVEAIRERLLADLAVIQPRAASIPVLSTVTGAWL-DTTV 774 Query: 2335 LDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVAS 2394 +DA+YW R+ RQ V+F + RT+ +EI P PVLT A + A A + Sbjct: 775 MDAEYWYRNLRQTVEFEAATRTLLDQDHRYFVEISPHPVLTTAIQETLDVTDTAAVATGT 834 Query: 2395 LRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSI--- 2451 LR+ R+ ALA G P + A++ R +LPTYPFQR R+W +SS+ Sbjct: 835 LRRNEGSLRRFQLALAELVTRGLTPHWPALYPDARH-TDLPTYPFQRERYWVGSSSVRDA 893 Query: 2452 ----AVDGGTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAM 2507 D T + SG+ G L++ + HV VV G T Sbjct: 894 APAPQPDPATGRAAGPASGRAAVDGGDGPAELLAL-----VRAHV----AVVLGET---- 940 Query: 2508 ALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGER----- 2562 TP + ++ + S E++ L A G S+ S + + P +R Sbjct: 941 ------TPDSVDPKLTFKQLGFDSVMSVELRNRLSSATGSSLPSTVLFNHPTPDRLARHL 994 Query: 2563 GADWSLNAEGTVDTAGSDPDAAADE 2587 A+ S EG D A P AADE Sbjct: 995 SAEASSQVEGAHDAA---PTGAADE 1016 Score = 594 bits (1531), Expect = e-166 Identities = 373/946 (39%), Positives = 510/946 (53%), Gaps = 26/946 (2%) Query: 13 SFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRA 72 + AIIG + R P A + +E+W LLR+G I++VP RWD FD + STPG + TR Sbjct: 8 AIAIIGMSCRLPRAVNPQEFWELLRNGESGITEVPPQRWDANSLFDAERSTPGTMNTRWG 67 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+D V FD FFG+S+RE MDPQ R+++E +W A+E + I P L ++ TGVFVG Sbjct: 68 GFIDGVDQFDPGFFGISSREAVAMDPQQRLVLELSWEALEDARIVPERLRHTATGVFVGA 127 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 DY + S + + GT + A R+SY LGLQGP++AVD+ SSSLV++H Sbjct: 128 IWDDYASLMSAR-GREAVTHHTVTGTHRSIIANRVSYALGLQGPSMAVDSGQSSSLVSVH 186 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 AC++LR E LALAGG N+ L P + I + L+PDGRC TFD A+GYVRGEG G Sbjct: 187 LACESLRRGESTLALAGGVNLNLVPESTIGMAKFGGLSPDGRCFTFDTRANGYVRGEGGG 246 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 VVV+K L DA+ D D I VIRGSA+N DG+ LT PN AQ V+ +A +RAG+ PA Sbjct: 247 VVVLKPLADAIADQDPIYCVIRGSAVNNDGSGENLTTPNSQAQAAVLREAYRRAGVDPAQ 306 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V Y+E HGTGT +GDPIEA+A G V+GA R P +PL +GSAKTNIGHLE Sbjct: 307 VQYVELHGTGTPVGDPIEAEALGAVIGAARPPGDPLWVGSAKTNIGHLEAAAGIAGLLKV 366 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 + + LP LNF T +P IP + L + V E W G+P +AGVS+FG GTNAH Sbjct: 367 VLSISHRELPASLNFATANPRIPLDSLNLRVGDELTSWPSAGRPMLAGVSAFGMGGTNAH 426 Query: 433 VILEEAPAVG--TPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLAD 490 ++E++P PA D LS + A+ A L R D Sbjct: 427 AVVEQSPVAARQIPAPGGTPTDQGGPVPWLLSGGSVAAVRGQAARLLSHLEGRSGLRAVD 486 Query: 491 VSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWLFTGQ 550 V + T R+ RA +V + + L ALA G+V G + + KT ++F GQ Sbjct: 487 VGWSLATTRSVFPHRAVVVADDGGYG-QSLAALAAGSVDAGVVEGLADVSGKTVFVFPGQ 545 Query: 551 GSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTY 610 GSQ+ GMA EL D VFAE + CA A+ + L DV+ ++DG L Sbjct: 546 GSQWVGMAVELLDGSEVFAEHMAACARALEPFVGWSLEDVL---RQVDGTWS--LDRVDV 600 Query: 611 AQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFG 670 QP L+AV + LA LWQ+ G EP V+GHS G+ +AACVAG +EDGAR++A R R Sbjct: 601 VQPVLWAVMVSLAGLWQAHGVEPAAVLGHSQGEIAAACVAGALSLEDGARVVALRSRAIA 660 Query: 671 SLPA--GGRMAAVFTAPERAERLTDEYPSLSVAAYNGANT-VLSGPAKDLESAVATLVAD 727 A GG ++ A E +T +++A NG ++ V++G LE+ L Sbjct: 661 EALAGHGGMLSIAAPATEVTALITPWGRQITIATVNGPHSVVVAGDPDALEALRGELETR 720 Query: 728 GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAY 787 G+R + +A H+ ++ I + + ++ R ++ TG+ L +T +D Y Sbjct: 721 GLRNRRIPVDYASHTPHVEAIRERLLADLAVIQPRAASIPVLSTVTGAWLD-TTVMDAEY 779 Query: 788 WRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV-LASLRPT 846 W R+ RQ VEF + RTL D + R +EI P PVLT TA+ D T V +LR Sbjct: 780 WYRNLRQTVEFEAATRTLLDQDHRYFVEISPHPVLT-TAIQETLDVTDTAAVATGTLRRN 838 Query: 847 TADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDR---- 902 R+ A+A G P + A PDAR DLPTYPF+ ++W + D Sbjct: 839 EGSLRRFQLALAELVTRGLTPHWPAL-YPDARHTDLPTYPFQRERYWVGSSSVRDAAPAP 897 Query: 903 DTQTASAGSVTPHRTQAVRLLEDGQIEELA------ALIDGETVDE 942 A+ + P +A DG E LA A++ GET + Sbjct: 898 QPDPATGRAAGPASGRAAVDGGDGPAELLALVRAHVAVVLGETTPD 943 Score = 160 bits (405), Expect = 4e-36 Identities = 122/369 (33%), Positives = 167/369 (45%), Gaps = 21/369 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPD-ESAQRAIDEITERHKCRIHTYAADV 3356 L+TGG G G A +LA+ GA ++LTSRR D E A E+TE R+ A DV Sbjct: 2204 LVTGGTGGAGTQVARWLARNGAEHLLLTSRRGRDAEGAAELAAELTEAG-VRVTVAACDV 2262 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D +A LLA + ELP L + H AGV+ A L + PE LA K GA+H Sbjct: 2263 ADRDALARLLAGVPDELP-LTAVIHAAGVVTTAPLDSTGPEELAEVLAGKVAGAAHLDAL 2321 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQA YA ANA LD L +R + G AT + +G WG G Sbjct: 2322 LGDRQLDAFVLFSSNAGVWGSGGQAAYAAANAYLDALAQQRSSMGQTATSVAWGAWGGAG 2381 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPI 3536 MA+ E + +G+I +DP A+ AL + + +G V +W R S RP Sbjct: 2382 MAAEEGFKERLRRRGIIEMDPELAVTALVQAVESGEASIAVADVDWARFVPGFTSNRPSP 2441 Query: 3537 LDLVLP---SAAGEA-------TGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLAS 3586 L LP A EA G S L +L + + +R + ++ EV + L + Sbjct: 2442 LIGDLPEVRDALREADSRPAVDQGGSALATRLAGLSVLERERVLLNLVRTEVASVLGHTT 2501 Query: 3587 PPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPT----IGGLAEYLV 3640 +R F +LG DSL+A+E R RL++ G + + FD+PT G L E Sbjct: 2502 ADMVDARRPFRELGFDSLIAVEFRGRLNAATG--LRLPTSVAFDHPTPAELAGHLRELFA 2559 Query: 3641 GQLPDAEAP 3649 G D P Sbjct: 2560 GSRGDTAMP 2568 Score = 41.6 bits (96), Expect = 2.4 Identities = 43/168 (25%), Positives = 73/168 (43%), Gaps = 14/168 (8%) Query: 3474 QGGMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSAR 3533 +G + + A A + +GL P P+ A + Q + W ++ V +A Sbjct: 839 EGSLRRFQLALAELVTRGLTPHWPALYPDARHTDLPTYPFQR---ERYWVGSSSVRDAAP 895 Query: 3534 PPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSR 3593 P D AAG A+G + + + ++ V L +P + + Sbjct: 896 APQPDPATGRAAGPASGRAA-------VDGGDGPAELLALVRAHVAVVLGETTPDSVDPK 948 Query: 3594 --FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 F LG DS+M++ELRNRL S G ++ +T +F++PT LA +L Sbjct: 949 LTFKQLGFDSVMSVELRNRLSSATGS--SLPSTVLFNHPTPDRLARHL 994 Score = 41.6 bits (96), Expect = 2.4 Identities = 56/169 (33%), Positives = 76/169 (44%), Gaps = 17/169 (10%) Query: 1024 DEAQLVDTLRAASAGELYVVH-IAAGDGAAAPMRDLLR-VQHRTLGGLRRLFRAANDAEL 1081 D A+L D +SA VV +A G GAA D +R V ++ L ++ A+D Sbjct: 5612 DLAELRDRTGPSSAFPAVVVAPVATGTGAAP---DAVREVTYQVLDMIQSWL--ADDRSA 5666 Query: 1082 RSPIWLVTRDGQRVTDTDTVVP-EQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI 1140 S + LVTR D +V Q+ +WG RAA E P + L DL G++ P Sbjct: 5667 SSTLLLVTRGAVSTGFGDDLVDLGQAAVWGLVRAAQSENPDRF-VLLDLDGSEPVGPLPT 5725 Query: 1141 ARITSPRDGEDQIALRGDAVYAPRLVRRTGE-----PSDTPLPVREDRT 1184 A + S GE Q+A R V RL R + + P P P R D T Sbjct: 5726 AALLS---GEPQLAFREGKVLTARLDRVSSDAGTLLPPAGPDPWRLDVT 5771 >tr|D3Y1I4|D3Y1I4_9ACTO Tax_Id=529089 SubName: Full=TamAII;[Streptomyces sp. 307-9] Length = 3365 Score = 1554 bits (4023), Expect = 0.0 Identities = 1072/3012 (35%), Positives = 1499/3012 (49%), Gaps = 180/3012 (5%) Query: 15 AIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AIIG + RFPG S E+ W ++ +GR+AIS P +R WD+E +D DP G R Sbjct: 36 AIIGMSCRFPGDVRSPEDLWQVVAEGRDAISAFPDNRGWDLEALYDADPDRSGTSYVREG 95 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FD FFG+S RE MDPQ R+L+ET+W A E +GI P SL S GVFVG Sbjct: 96 GFLYDAADFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPQSLRGSKAGVFVGS 155 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 DY + E+E ++ IG + + +GR++Y LGL+GPAV VDTACSSSLVA+H Sbjct: 156 NYQDYANRLPE--VPAELEGHLGIGNTPSVVSGRVAYTLGLEGPAVTVDTACSSSLVALH 213 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 AC ALR +C +ALAGG +V+ +PA+ I FS LAPD R K F + ADG EG G Sbjct: 214 LACHALRQGDCSMALAGGISVMSSPASFIEFSRQRGLAPDARVKAFASGADGTALSEGIG 273 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 +++V+RL DA +G R+ +VIRGSAINQDGAS GLT PNG +Q+RVI AL A L P Sbjct: 274 MLLVERLSDARHNGHRVLSVIRGSAINQDGASNGLTAPNGPSQERVIRQALAAARLTPDQ 333 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT LGDPIEAQA G R + PL +GS K+NIGH + Sbjct: 334 VDAVEAHGTGTKLGDPIEAQALIATYGQDRPADRPLWLGSVKSNIGHTQAAAGAASIIKM 393 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 L+ LP+ L+ + PS I WE + ++ E V W +PR G+SSFG +GTNAH Sbjct: 394 VMALDQGLLPRTLHVDEPSSRIDWEAGAVSLLTEDVRWPALDRPRRVGISSFGISGTNAH 453 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRAHPQARLAD 490 +LEEAP V E +D V+P +SART EAL A + R+++ P A Sbjct: 454 AVLEEAPPVEADEENEDRDDATPAGVVPWVISARTAEALRAQARQLREYVDQRPDLDTAA 513 Query: 491 VSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGES-HEAPKTAWLFTG 549 V+H T R+ E RA + S ++ L ALA P+P +V+G + E +T +F G Sbjct: 514 VAHALATTRSAFEHRAVALGGSTGELLKALDALAHGEPSPHVVQGVAPDETGRTVLVFPG 573 Query: 550 QGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTT 609 QG+Q+ GM EL D PVFAE++ +C EA+A ++ L +V+ +LD Sbjct: 574 QGTQWAGMGAELLDAVPVFAESIARCEEALAPYVDWSLTEVLRSGADLD--------RVD 625 Query: 610 YAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLF 669 QP +AV + LA WQ G PD VVGHS G+ +AA VAG +ED A+++A R R+ Sbjct: 626 VIQPVTWAVMVSLAAAWQELGVRPDAVVGHSQGEIAAAAVAGALTLEDAAKVVAVRARII 685 Query: 670 GSLPAG-GRMAAVFTAPERAERLTDEYPSLSVAAYNGAN-TVLSGPAKDLESAVATLVAD 727 G AG G MA++ + E + + +AA NG N TV+SG +E+ VA L Sbjct: 686 GEHLAGRGAMASIPQPVQAVEEILTT--GVGIAAVNGPNATVVSGDKDAVEALVAQLQEQ 743 Query: 728 GVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAY 787 VR + +A HSA ++ I ++ P I + ++ LD Y Sbjct: 744 DVRARLIPVDYASHSAHVEAIEAQLADALAGIQ-PHPADIPFFSTVDPGFLNTSDLDAGY 802 Query: 788 WRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTT 847 W R+ RQ V F +++ L + +E PVLT + + + +LR Sbjct: 803 WYRNLRQTVHFHTAIQQLTEAGHTTYIESSAHPVLTYSI----EETEGAQTITGTLRRGE 858 Query: 848 ADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTA 907 ++ + A + GH ++ + R +DLPTYPF+H+++W ID TA Sbjct: 859 GTLTRLLTSAAHLHTHGHPVNWPIGK--GGRHVDLPTYPFQHQRYW------IDVPDTTA 910 Query: 908 SAGSVTPHRTQAVRLLEDGQIEELAALIDGETV--DEQTLRVLNKLAARHNQQRSTHVDP 965 + V R E + E+ +L D V D VL LA+ ++R Sbjct: 911 APAPVPATDIVDTRFWEAVENEDWESLADTLAVPDDASLSTVLPALASWRQERRREATVN 970 Query: 966 DARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRHQIVALP----GS 1021 D RY I W W++V + A + G RH +P S Sbjct: 971 DWRYGISWKPVADGGATTRLGGTWLVVFPEGRATDDVVRTAAEGLARHGAQVVPLELNAS 1030 Query: 1022 DADEAQLVDT----LRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAAN 1077 +A VD L A + V+ A D + PM + + G L +A Sbjct: 1031 EAARGTYVDLIGEKLSAQDSPPAGVLSFLALDESPHPMHPAMTAG---VAGTLALVQALG 1087 Query: 1078 DAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELPHIWGGLADLSGA--DT 1134 DA L P+W T V +D V P Q+ +WG GR ALE P WGGL DL D Sbjct: 1088 DARLEVPVWFGTCGAVAVGASDAVTSPAQAQVWGLGRVVALEQPERWGGLVDLPRELDDR 1147 Query: 1135 EWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPV------REDRTYLVT 1188 RL A + + GE+Q+A+R V+A RLVR P D P R T LVT Sbjct: 1148 ARARLCA-VLAGLAGEEQVAVRSSGVFARRLVRN---PLDVRTPEQAAPGWRTSGTALVT 1203 Query: 1189 GGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAH 1248 GG GA+G +A +LAS+GA HVVLTSRR P + V D AD Sbjct: 1204 GGTGALGPHIARWLASNGAEHVVLTSRRGPSAPGMAELATELAAEGVRLTVAACDAADRE 1263 Query: 1249 DVARLMTTVAAELPPLAGIVHAAG--EIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALT 1306 +A ++ + A+ L +VHAA E+ + SGLD E V A KV GA HL E L Sbjct: 1264 ALAGVLEQLKADGESLRTVVHAAAFIELASLAESGLD--EFADVLAAKVAGAAHLDELLG 1321 Query: 1307 DLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG- 1365 DLD FV SSIA VWG AY AANA+L+ LA + R RG+ A S+ +G W Sbjct: 1322 G--DDLDAFVLFSSIAGVWGSGDHGAYAAANAYLNALAEQRRARGLKASSIAWGVWNVWD 1379 Query: 1366 ---MADAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGV-VAKIDWSRFLPLYQQAGR 1421 + + +L+ RG+ L P A A M ++A V VA++DW RF+P++ AG Sbjct: 1380 PERLPEGVKPEQLQARGLPFLDPDTAFAAMRQILAHDETFVAVAEVDWERFVPVFTSAGP 1439 Query: 1422 RAFLS-------ELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNA 1474 R L+ E+E+ L ++L ++R ++ +R+ Sbjct: 1440 RPLLAGVPEAQREIEAATSSPGTASGADAPSAPSSPLRDRLEGLAAEERDRVLLELVRDQ 1499 Query: 1475 VAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAAD 1533 A V + + F DLG DSL AVELR R+ G +P TLV D+P A Sbjct: 1500 AASVLGHASGEAVEPGRAFRDLGFDSLTAVELRNRLNTATGLRLPATLVFDYPSPGVLAA 1559 Query: 1534 YLLVEVLGLGEQT----NVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGV 1588 +L E G T T+ A DDPI ++ + CRFPG PE WELL G Sbjct: 1560 HLRDEFFGALPGTAPAGTAAAPPTLPAADDDPIVIIGMGCRFPGGVRSPEELWELLLRGG 1619 Query: 1589 DAIREVPEDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQ 1647 D I +P DR WD+D YDPDP+ GK+YTR P FFGISPREA+ ++PQ Sbjct: 1620 DVISGLPTDRGWDLDALYDPDPEQRGKSYTRHGGFLYDAADFDPAFFGISPREALAMDPQ 1679 Query: 1648 QRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNAL 1707 QRL+LET WE ERAG P LRGSRT VF GV+ ++Y L E+ ++IE + TGN Sbjct: 1680 QRLLLETSWEAFERAGINPQSLRGSRTSVFAGVSYHDYGSRLG-ETPEEIEGYLGTGNTA 1738 Query: 1708 NAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTV 1767 + SGRV++ LG EG AV +DT CSS+LVA+H A Q+L+ G+ LALAGGV+V+ P + Sbjct: 1739 SIASGRVSYVLGLEGAAVTLDTGCSSSLVALHLAAQSLRQGESTLALAGGVSVMAVPTSF 1798 Query: 1768 VAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQ 1827 SR R LS GRC+ F A ADG SEG G+L+L+RLSDA R+G RV AV+ +++NQ Sbjct: 1799 TEFSRQRGLSVDGRCRAFSADADGMGMSEGVGMLLLERLSDARRNGHRVLAVVRGTAMNQ 1858 Query: 1828 DGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXX 1887 DGAS+GLT PNG +QQR+I LA AGL+ VD +EAHGTGT LGDPIE Q Sbjct: 1859 DGASNGLTAPNGPSQQRVIRQALANAGLAPDQVDAVEAHGTGTKLGDPIEAQALIATHGQ 1918 Query: 1888 XXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALP 1947 PL +GSVK+NIGHT++ASG AGLIK+V++LQHGVLP++LH P+P + W A Sbjct: 1919 DRPADRPLWLGSVKSNIGHTQAASGVAGLIKMVMALQHGVLPKTLHVGEPTPKVDWSAGA 1978 Query: 1948 VRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGT 2007 V ++ E W + G+ RRAGVSSFG +GTN H ++E+AP Sbjct: 1979 VALLTEETAWPSTGQPRRAGVSSFGISGTNTHAVLEQAPDD--------------EPVSV 2024 Query: 2008 DDSPQVL--ALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVV 2065 +SP V+ +SAR+ EAL AR+ +++ PGLD A V T GR+ FE+RA ++ Sbjct: 2025 SESPGVVPWVISARTAEALRAQARQLREYVEQRPGLDTAAVADTLINGRALFEHRAVVLA 2084 Query: 2066 DSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQ 2125 ++ +V+G+ T ++F GQG+Q+ GM EL D P FA+ Sbjct: 2085 EAPDAVAAALDALAAGQPHTHLVQGQAKAVGKTVFVFPGQGTQWAGMGAELLDAVPAFAE 2144 Query: 2126 TVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEP 2185 ++ +C EA+A + L +VL R D L + QP +AV + LA WQ + P Sbjct: 2145 SIARCEEALAPYVDWSLTEVL----RSGTD-LDRVNVIQPVTWAVMVSLAATWQHLGVRP 2199 Query: 2186 DVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEG-GRMVAVFADAEHVEQVA 2244 D V+GHS G+ AAA VAG SL+D A+++A R R+ G G G M ++ + VE+ Sbjct: 2200 DAVVGHSQGEIAAAAVAGALSLEDAAKVVAVRARIIGEHLAGLGTMASIPQSVQTVEEHL 2259 Query: 2245 GEFPRVSVGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDX 2303 VS+ A NGPN TV+SG + +E +V + + IR + +A HS ++ + Sbjct: 2260 TS--GVSIAAANGPNTTVISGDKDAVETLVADLQGQDIRARIIPVDYASHSAHVEAIKAQ 2317 Query: 2304 XXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCS 2363 +P L +T LDA YW R+ RQ V F +++ + G + Sbjct: 2318 LADALAGIQPHPADIPFFSAVEPGFLNTET-LDAGYWYRNLRQTVHFHTAIQQLTEAGHT 2376 Query: 2364 VLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAA 2423 +E PVLT + E A +LR+G ++ + A + GH ++ Sbjct: 2377 TYIESSAHPVLTYSI----EETEGAQTITGTLRRGEGTLTRLLTSAAHLHTHGHPVNWPI 2432 Query: 2424 VHRQPRRPVELPTYPFQRRRFW----PKASSIAVDGGTAASG--ILGSGKDLASGDT-IY 2476 + R V+LPTYPFQ +R+W P + + G AA+G +LG+ +LA D ++ Sbjct: 2433 --GKGGRHVDLPTYPFQHQRYWINPTPDSRTNLSGAGLAAAGHPLLGAAVELAGTDAHLF 2490 Query: 2477 TSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKA 2533 T RLS++S PWLADH + GTV++PG + +AL A VG ++++ P+ILPE+ Sbjct: 2491 TGRLSLQSHPWLADHAVSGTVLLPGTGFLELALQAGHRVGC-GTVEELTLEAPLILPERG 2549 Query: 2534 SREVQLTLHPADGGSVLSFQIHSRPYGERGAD--WSLNAEGTVDTAGSDPDAAADEQSDP 2591 +VQL + D +HSR + G+D W+ +A GT+ A P AD + P Sbjct: 2550 GLDVQLNVGAPDDSGRREMTLHSRAQ-DAGSDEPWTRHATGTLTPAAESPRPDADLTAWP 2608 Query: 2592 VDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLG 2651 E + + ++ A+ +GP + G L++ W E ++ + E + + Sbjct: 2609 P----AGAEPVETEGYYDRLAEQGYGYGPAFHG-LRAAWRRGDEVFAEVALPEEESAEAT 2663 Query: 2652 SEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHR 2711 +HP LMD G LP + VTL R Sbjct: 2664 GYGIHPALMD----AALHALGLGVLAAAGEGRARLPFSWSGVTLHAAGAAALRVRV---- 2715 Query: 2712 SALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPP 2771 + L + D G + E V R A L G L+ + W VP Sbjct: 2716 APLGDAEDTVSVTVADPAGMPV-ATAESLVVRPVVTAQLEAAGSSVNDSLFRMDW--VPA 2772 Query: 2772 PPSADD-AVGTWLIAG---------FDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGA 2821 A W + G +E A V +D L V+ +V+ +A Sbjct: 2773 SAGLSPVAARRWAVVGPDPLRVGRTLEETGATVFAADDLDSVATLDVVPDVVVVPYA--- 2829 Query: 2822 GFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGGLWIVTEHGV 2881 P + + +L+ A + + L ++T + V Sbjct: 2830 -----------PQQDGTDKLAARVHEVLYGVLDLVKRWLAEERFA---DSRLALLTRNAV 2875 Query: 2882 ACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGIQEPEI 2941 + D AA+WG R+ +E P RLV D D EP+I Sbjct: 2876 VTSPDDTPDLEHAAIWGLIRSAQSEHPD---RLVLIDTDHHTPDLPTALTTG----EPQI 2928 Query: 2942 AVRQGKLLASRL 2953 A+R GK L RL Sbjct: 2929 AIRDGKYLVPRL 2940 Score = 610 bits (1573), Expect = e-171 Identities = 360/902 (39%), Positives = 503/902 (55%), Gaps = 26/902 (2%) Query: 1549 RQASTVTARTDDPIAVVAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYD 1606 R+ A+ +PIA++ +SCRFPG PE W+++A G DAI P++R WD++ YD Sbjct: 22 RRLGEAEAKDHEPIAIIGMSCRFPGDVRSPEDLWQVVAEGRDAISAFPDNRGWDLEALYD 81 Query: 1607 PDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP 1666 DPD G +Y R P FFGISPREA+ ++PQQRL+LET WE ERAG P Sbjct: 82 ADPDRSGTSYVREGGFLYDAADFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDP 141 Query: 1667 SDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVA 1726 LRGS+ GVF G +YA+ L E ++E H GN + +SGRVA+ LG EGPAV Sbjct: 142 QSLRGSKAGVFVGSNYQDYANRL-PEVPAELEGHLGIGNTPSVVSGRVAYTLGLEGPAVT 200 Query: 1727 VDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFD 1786 VDTACSS+LVA+H AC AL+ GDC +ALAGG++V+ SP + + SR R L+P R K F Sbjct: 201 VDTACSSSLVALHLACHALRQGDCSMALAGGISVMSSPASFIEFSRQRGLAPDARVKAFA 260 Query: 1787 ASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLI 1846 + ADG SEG G+L+++RLSDA +G RV +VI S++NQDGAS+GLT PNG +Q+R+I Sbjct: 261 SGADGTALSEGIGMLLVERLSDARHNGHRVLSVIRGSAINQDGASNGLTAPNGPSQERVI 320 Query: 1847 EATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGH 1906 LA A L+ VD +EAHGTGT LGDPIE Q PL +GSVK+NIGH Sbjct: 321 RQALAAARLTPDQVDAVEAHGTGTKLGDPIEAQALIATYGQDRPADRPLWLGSVKSNIGH 380 Query: 1907 TESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRA 1966 T++A+GAA +IK+V++L G+LP++LH + PS I W+A V ++ E V W R RR Sbjct: 381 TQAAAGAASIIKMVMALDQGLLPRTLHVDEPSSRIDWEAGAVSLLTEDVRWPALDRPRRV 440 Query: 1967 GVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVE 2026 G+SSFG +GTNAH ++EEAPP T +SAR+ EAL Sbjct: 441 GISSFGISGTNAHAVLEEAPP------VEADEENEDRDDATPAGVVPWVISARTAEALRA 494 Query: 2027 LARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAG 2086 AR+ +++ P LD A V H RS FE+RA + S Sbjct: 495 QARQLREYVDQRPDLDTAAVAHALATTRSAFEHRAVALGGSTGELLKALDALAHGEPSPH 554 Query: 2087 VVRGEHVHRP-TTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDV 2145 VV+G T +F GQG+Q+ GM EL D PVFA+++ +C EA+A + L +V Sbjct: 555 VVQGVAPDETGRTVLVFPGQGTQWAGMGAELLDAVPVFAESIARCEEALAPYVDWSLTEV 614 Query: 2146 LFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVF 2205 L R AD L QP +AV + LA WQ + PD V+GHS G+ AAA VAG Sbjct: 615 L----RSGAD-LDRVDVIQPVTWAVMVSLAAAWQELGVRPDAVVGHSQGEIAAAAVAGAL 669 Query: 2206 SLDDGARLMAERGRMFGS-LPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPN-TVLS 2263 +L+D A+++A R R+ G L G M ++ + VE++ V + A NGPN TV+S Sbjct: 670 TLEDAAKVVAVRARIIGEHLAGRGAMASIPQPVQAVEEIL--TTGVGIAAVNGPNATVVS 727 Query: 2264 GPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCN 2323 G + +E +V + +++ +R + +A HS ++ + +P Sbjct: 728 GDKDAVEALVAQLQEQDVRARLIPVDYASHSAHVEAIEAQLADALAGIQPHPADIPFFST 787 Query: 2324 RTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWP 2383 L + LDA YW R+ RQ V F +++ + G + +E PVLT + Sbjct: 788 VDPGFL-NTSDLDAGYWYRNLRQTVHFHTAIQQLTEAGHTTYIESSAHPVLTYSI----E 842 Query: 2384 EHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRR 2443 E A +LR+G ++ + A + GH ++ + R V+LPTYPFQ +R Sbjct: 843 ETEGAQTITGTLRRGEGTLTRLLTSAAHLHTHGHPVNWPI--GKGGRHVDLPTYPFQHQR 900 Query: 2444 FW 2445 +W Sbjct: 901 YW 902 Score = 602 bits (1552), Expect = e-169 Identities = 359/911 (39%), Positives = 496/911 (54%), Gaps = 35/911 (3%) Query: 7 PIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTP 64 P IIG RFPG S EE W LL G + IS +P DR WD++ +DPDP Sbjct: 1585 PAADDDPIVIIGMGCRFPGGVRSPEELWELLLRGGDVISGLPTDRGWDLDALYDPDPEQR 1644 Query: 65 GKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANS 124 GK TR GF+ D FD FFG+S RE MDPQ R+L+ET+W A E +GI P SL S Sbjct: 1645 GKSYTRHGGFLYDAADFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGINPQSLRGS 1704 Query: 125 NTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTAC 184 T VF G++ HDY + T EIE Y+ G + + A+GR+SY LGL+G AV +DT C Sbjct: 1705 RTSVFAGVSYHDYGSRLGE--TPEEIEGYLGTGNTASIASGRVSYVLGLEGAAVTLDTGC 1762 Query: 185 SSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADG 244 SSSLVA+H A Q+LR E LALAGG +V+ P + FS L+ DGRC+ F A ADG Sbjct: 1763 SSSLVALHLAAQSLRQGESTLALAGGVSVMAVPTSFTEFSRQRGLSVDGRCRAFSADADG 1822 Query: 245 YVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALK 304 EG G+++++RL DA R+G R+ AV+RG+A+NQDGAS GLT PNG +QQRVI AL Sbjct: 1823 MGMSEGVGMLLLERLSDARRNGHRVLAVVRGTAMNQDGASNGLTAPNGPSQQRVIRQALA 1882 Query: 305 RAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXX 364 AGL P V +EAHGTGT LGDPIEAQA G R + PL +GS K+NIGH + Sbjct: 1883 NAGLAPDQVDAVEAHGTGTKLGDPIEAQALIATHGQDRPADRPLWLGSVKSNIGHTQAAS 1942 Query: 365 XXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSF 424 L++ LPK L+ P+P + W + ++ E W G+PR AGVSSF Sbjct: 1943 GVAGLIKMVMALQHGVLPKTLHVGEPTPKVDWSAGAVALLTEETAWPSTGQPRRAGVSSF 2002 Query: 425 GFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRA 482 G +GTN H +LE+AP EPV V+P +SART EAL A + R+++ Sbjct: 2003 GISGTNTHAVLEQAP------DDEPVSVSESPGVVPWVISARTAEALRAQARQLREYVEQ 2056 Query: 483 HPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPK 542 P A V+ T RA E RA ++ + ++ L ALA +P LV+G++ K Sbjct: 2057 RPGLDTAAVADTLINGRALFEHRAVVLAEAPDAVAAALDALAAGQPHTHLVQGQAKAVGK 2116 Query: 543 TAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTE 602 T ++F GQG+Q+ GM EL D P FAE++ +C EA+A ++ L +V+ +LD Sbjct: 2117 TVFVFPGQGTQWAGMGAELLDAVPAFAESIARCEEALAPYVDWSLTEVLRSGTDLD---- 2172 Query: 603 SPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLI 662 QP +AV + LA WQ G PD VVGHS G+ +AA VAG +ED A+++ Sbjct: 2173 ----RVNVIQPVTWAVMVSLAATWQHLGVRPDAVVGHSQGEIAAAAVAGALSLEDAAKVV 2228 Query: 663 AERGRLFGSLPAG-GRMAAVFTAPERAERLTDEYPS-LSVAAYNGAN-TVLSGPAKDLES 719 A R R+ G AG G MA++ P+ + + + S +S+AA NG N TV+SG +E+ Sbjct: 2229 AVRARIIGEHLAGLGTMASI---PQSVQTVEEHLTSGVSIAAANGPNTTVISGDKDAVET 2285 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 VA L +R + +A HSA ++ I ++ P I + Sbjct: 2286 LVADLQGQDIRARIIPVDYASHSAHVEAIKAQLADALAGIQ-PHPADIPFFSAVEPGFLN 2344 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 + LD YW R+ RQ V F +++ L + +E PVLT + + + Sbjct: 2345 TETLDAGYWYRNLRQTVHFHTAIQQLTEAGHTTYIESSAHPVLTYSI----EETEGAQTI 2400 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRA 899 +LR ++ + A + GH ++ + R +DLPTYPF+H+++W N Sbjct: 2401 TGTLRRGEGTLTRLLTSAAHLHTHGHPVNWPIGK--GGRHVDLPTYPFQHQRYWI--NPT 2456 Query: 900 IDRDTQTASAG 910 D T + AG Sbjct: 2457 PDSRTNLSGAG 2467 Score = 144 bits (362), Expect = 3e-31 Identities = 117/380 (30%), Positives = 167/380 (43%), Gaps = 27/380 (7%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 L+TGG GA+G H A +LA GA +VLTSRR P + R+ A D Sbjct: 1201 LVTGGTGALGPHIARWLASNGAEHVVLTSRRGPSAPGMAELATELAAEGVRLTVAACDAA 1260 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A +L +++A+ L + H A ++ A L+ + F LA K GA+H Sbjct: 1261 DREALAGVLEQLKADGESLRTVVHAAAFIELASLAESGLDEFADVLAAKVAGAAHLDELL 1320 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWG--QG 3475 YA ANA L+ L +RRA+GL A+ I +G W Sbjct: 1321 GGDDLDAFVLFSSIAGVWGSGDHGAYAAANAYLNALAEQRRARGLKASSIAWGVWNVWDP 1380 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPP 3535 + A+GL LDP A A+ +++A+ V + +W+R V SA P Sbjct: 1381 ERLPEGVKPEQLQARGLPFLDPDTAFAAMRQILAHDETFVAVAEVDWERFVPVFTSAGPR 1440 Query: 3536 ILDLVLP----------SAAGEATG-------DSELLKQLMEIPIPQRAGFVTEFLQREV 3578 L +P S+ G A+G S L +L + +R + E ++ + Sbjct: 1441 PLLAGVPEAQREIEAATSSPGTASGADAPSAPSSPLRDRLEGLAAEERDRVLLELVRDQA 1500 Query: 3579 QNFLRLASPPAA--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLA 3636 + L AS A F DLG DSL A+ELRNRL++ G + AT VFDYP+ G LA Sbjct: 1501 ASVLGHASGEAVEPGRAFRDLGFDSLTAVELRNRLNTATG--LRLPATLVFDYPSPGVLA 1558 Query: 3637 EYL----VGQLPDAEAPETA 3652 +L G LP TA Sbjct: 1559 AHLRDEFFGALPGTAPAGTA 1578 Score = 139 bits (350), Expect = 8e-30 Identities = 135/475 (28%), Positives = 194/475 (40%), Gaps = 29/475 (6%) Query: 1063 HRTLGGLRRLFRA--ANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELP 1120 H L G+ L + A + S + L+TR+ + DT E + +WG R+A E P Sbjct: 2843 HEVLYGVLDLVKRWLAEERFADSRLALLTRNAVVTSPDDTPDLEHAAIWGLIRSAQSEHP 2902 Query: 1121 HIWGGLADLSGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPV- 1179 L D P L +T+ GE QIA+R PRL R T P+ P Sbjct: 2903 D----RLVLIDTDHHTPDLPTALTT---GEPQIAIRDGKYLVPRLARTTLHPAPESTPAF 2955 Query: 1180 REDRTYLVTGGLGAIGLEVAGYLASHG-AGHVVLTSRREPXXXXXXXXXXXXEQYACDVR 1238 D T L+TG G + +A +L +H ++VL SRR + Sbjct: 2956 HPDSTVLITGATGTLAGLLAHHLVTHHHVQNLVLLSRRPAHTLATTL-----NELGAHTT 3010 Query: 1239 VITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGA 1298 ++T DV D + +T P+ ++H A + L L +D V K+ GA Sbjct: 3011 LVTGDVTDPDTLTHTLTH-----HPITAVIHTAATLHDATLDTLTTHHLDTVLNPKLDGA 3065 Query: 1299 WHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVN 1358 L E T L+ F+ SS A+ +GG GQ AY AAN FLD LA G A+S+ Sbjct: 3066 LLLHELTTQHTPHLEAFILFSSAAATFGGPGQAAYAAANTFLDTLAHHRHTHGQPALSLG 3125 Query: 1359 FGPW-----AAGMADAESRARLEQRGVRTLSPAEALAGM-ADVVAGPVQGVVAKIDWSRF 1412 +G W G R+ + GV LS AE LA A +G + ++D + Sbjct: 3126 WGLWEDRSTMTGNLTHTDLHRMTRHGVAGLSAAEGLALFDAACASGEPHLLPIRLDVAAL 3185 Query: 1413 LPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR 1472 A L L ++ L E+L + +QR + + + Sbjct: 3186 RRRADDDSLPALLRGL-AQRRVRRHTAEAGMRRPAELSLAERLARVSGEQRAQALEDLVV 3244 Query: 1473 NAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHP 1526 VA V + + F D+G DSL AVELR R+ G +P TLV D P Sbjct: 3245 TQVAAVLGYASTAAVEPDRAFKDIGFDSLTAVELRNRLNTATGLRLPATLVFDQP 3299 Score = 82.4 bits (202), Expect = 1e-12 Identities = 102/380 (26%), Positives = 147/380 (38%), Gaps = 37/380 (9%) Query: 3294 DRSYLITGGLGAI-GLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHT- 3351 D + LITG G + GL + ++VL SRR P + ++E+ HT Sbjct: 2958 DSTVLITGATGTLAGLLAHHLVTHHHVQNLVLLSRR-PAHTLATTLNELGA------HTT 3010 Query: 3352 -YAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGA 3410 DV D + L P+ + H A L DA L T L PK GA Sbjct: 3011 LVTGDVTDPDTLTHTLTH-----HPITAVIHTAATLHDATLDTLTTHHLDTVLNPKLDGA 3065 Query: 3411 S--HXXXXXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGIN 3468 H PGQA YA AN LD L R G A + Sbjct: 3066 LLLHELTTQHTPHLEAFILFSSAAATFGGPGQAAYAAANTFLDTLAHHRHTHGQPALSLG 3125 Query: 3469 FGPWGQGGMASSEAATANI---TAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRA 3525 +G W + ++ T G+ L + L AL + A SG+ +L A Sbjct: 3126 WGLWEDRSTMTGNLTHTDLHRMTRHGVAGLSAAEGL-ALFDA-ACASGEPHLLPIRLDVA 3183 Query: 3526 A---KVLGSARPPILDLVLPSAAGEATGDS--------ELLKQLMEIPIPQRAGFVTEFL 3574 A + + P +L + T ++ L ++L + QRA + + + Sbjct: 3184 ALRRRADDDSLPALLRGLAQRRVRRHTAEAGMRRPAELSLAERLARVSGEQRAQALEDLV 3243 Query: 3575 QREVQNFLRLASPPAA--SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTI 3632 +V L AS A F D+G DSL A+ELRNRL++ G + AT VFD PT Sbjct: 3244 VTQVAAVLGYASTAAVEPDRAFKDIGFDSLTAVELRNRLNTATG--LRLPATLVFDQPTP 3301 Query: 3633 GGLAEYLVGQLPDAEAPETA 3652 +A ++ +L E +TA Sbjct: 3302 QAIARFVERKLFPQETAQTA 3321 Score = 40.0 bits (92), Expect = 7.0 Identities = 62/243 (25%), Positives = 88/243 (36%), Gaps = 37/243 (15%) Query: 2754 GGDATRLLYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPID-------RNTDL 2806 GG TRL T W V P A D V G A+V VP++ R T + Sbjct: 984 GGATTRLGGT--WLVVFPEGRATDDVVRTAAEGLARHGAQV---VPLELNASEAARGTYV 1038 Query: 2807 QVLGEVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPS 2866 ++GE LS + AG + +P + L+ V A Sbjct: 1039 DLIGEKLSAQDSPPAGVLSFLALDESP--------HPMHPAMTAGVAGTLALVQALGDAR 1090 Query: 2867 VKLPGGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVD 2925 +++P +W T VA + + V P QA +WG GR E+P LVD + Sbjct: 1091 LEVP--VWFGTCGAVAVGASDAVTSPAQAQVWGLGRVVALEQPERWGGLVDLPRELDDRA 1148 Query: 2926 XXXXXXXXPGIQ-EPEIAVRQGKLLASRLL-------------PWARSGHLTLPRGGDFV 2971 G+ E ++AVR + A RL+ P R+ L GG Sbjct: 1149 RARLCAVLAGLAGEEQVAVRSSGVFARRLVRNPLDVRTPEQAAPGWRTSGTALVTGGTGA 1208 Query: 2972 LAP 2974 L P Sbjct: 1209 LGP 1211 >tr|D5PHA4|D5PHA4_9MYCO Tax_Id=525368 SubName: Full=Putative uncharacterized protein; Flags: Fragment;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 1124 Score = 1553 bits (4021), Expect = 0.0 Identities = 778/1136 (68%), Positives = 898/1136 (79%), Gaps = 22/1136 (1%) Query: 1 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD 60 M + E E T FAI+GYAAR PGAA A E+W +LR GR+A+S+VP +RW++++FFD D Sbjct: 1 MATVEDRPERTARFAIVGYAARVPGAADAAEFWDVLRHGRDAVSEVPGERWNVDDFFDSD 60 Query: 61 PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS 120 GK+V+RRAGFVDDV GFDAPFFG+SAREV LMDPQHR+L+ETAW+AVEH G APT+ Sbjct: 61 ADAAGKIVSRRAGFVDDVAGFDAPFFGVSAREVMLMDPQHRLLLETAWQAVEHWGTAPTA 120 Query: 121 LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV 180 LAN+NTGVFVGL+THDYL M SDEL+Y EI+AYMAIGT+ AAAAGRISYRLGLQGPAV V Sbjct: 121 LANTNTGVFVGLSTHDYLSMVSDELSYDEIDAYMAIGTAAAAAAGRISYRLGLQGPAVTV 180 Query: 181 DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA 240 DTACSSSLVA+HQACQALRL ECD+ALAGGANVLL+PATMITFS AHMLAPDGRCKTFDA Sbjct: 181 DTACSSSLVAVHQACQALRLGECDVALAGGANVLLSPATMITFSRAHMLAPDGRCKTFDA 240 Query: 241 AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA 300 AADGYVRGEGCGV+V+KRL+DA+RDGDRIRAVIRGSA+NQDGASGGLTVPNGVAQQRVIA Sbjct: 241 AADGYVRGEGCGVIVLKRLDDAIRDGDRIRAVIRGSAVNQDGASGGLTVPNGVAQQRVIA 300 Query: 301 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL 360 +AL+RAG+ DVGYLEAHGTGTSLGDPIE QAA V G GR P+ PLLIGS KTNIGHL Sbjct: 301 EALERAGVSAHDVGYLEAHGTGTSLGDPIEVQAAAAVFGEGRDPDRPLLIGSVKTNIGHL 360 Query: 361 EXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG 420 E LE+E LPKHLNF PSP+IPW+RL + V+ E WQRNG+PR+AG Sbjct: 361 EAAAGIAGIIKVVLSLEHEQLPKHLNFRNPSPYIPWDRLAVRVLDEATGWQRNGRPRVAG 420 Query: 421 VSSFGFAGTNAHVILEEAP------AVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAG 474 VSSFGF+GTNAHVILEEAP A G A EP + RR+SVLPLSARTP AL +LA Sbjct: 421 VSSFGFSGTNAHVILEEAPQEARANAAGPRAVVEP--EDRRFSVLPLSARTPAALAQLAD 478 Query: 475 EYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVR 534 YRDWL AHP+ L+++ TAG RAH E RAALVVNS ESA ELLGALADDRPAPGL+R Sbjct: 479 RYRDWLTAHPETDLSELCFTAGVGRAHFEHRAALVVNSTESATELLGALADDRPAPGLLR 538 Query: 535 GESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDA 594 GE + PKTAWLF GQGSQ+ GMARELF+TEPVFAET+ +CA V +LEKP+LDVIFD Sbjct: 539 GECDDRPKTAWLFPGQGSQFAGMARELFETEPVFAETMTRCAAVVDAVLEKPMLDVIFDV 598 Query: 595 DELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFD 654 D+ D LR T+YAQPALFAVELGLARLWQSWG EPDVV+GHSVGQY+AACVAGVF Sbjct: 599 DDPD-----TLRQTSYAQPALFAVELGLARLWQSWGLEPDVVLGHSVGQYAAACVAGVFS 653 Query: 655 VEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPA 714 +EDGA L+AERGRLFG+LPAGGRM A+F A ER E TDE+P LSVAAYNGANTVL+GPA Sbjct: 654 LEDGALLLAERGRLFGNLPAGGRMVAIFAAAERVESCTDEFPRLSVAAYNGANTVLAGPA 713 Query: 715 KDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTG 774 +DL+ VA L +DGVRCDWLDTSHAFHSALLDP LD+FE++A + +R PQR L+ NRTG Sbjct: 714 EDLDRVVAALTSDGVRCDWLDTSHAFHSALLDPALDEFEAYAGRFGFRSPQRTLVCNRTG 773 Query: 775 SALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPA 834 +ALGR+ +LD +YWRRHARQP+EFAKSV TLAD+NC VLLE+G +PVLTA AL AWPDPA Sbjct: 774 AALGRTAQLDASYWRRHARQPIEFAKSVATLADLNCAVLLEVGAQPVLTAAALRAWPDPA 833 Query: 835 TTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWF 894 T P+ +ASLR ADHRQI EA+ AY GHLP F A + RKLDLPTYPF+HR +WF Sbjct: 834 TAPRAIASLRRNGADHRQIAEALGGAYICGHLPAFGALQHGPTRKLDLPTYPFQHRHYWF 893 Query: 895 SDNRAIDRDTQTA-SAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAA 953 D+D Q+A + R++AVRLLE+G+IEELAAL+DG D QT VL +LAA Sbjct: 894 R-----DKDVQSAPTVAEAAVARSEAVRLLEEGRIEELAALLDGPNADPQTTEVLARLAA 948 Query: 954 RHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADALTAGGHRH 1013 +HNQ+R DARYEIRW+ DW+L+ DD A+ DALTA G Sbjct: 949 QHNQERGNQSIADARYEIRWEKSAAARADAGAGSDWLLIADDAEAIAPLVDALTAQGQPF 1008 Query: 1014 QIVALPGSDADEAQLVDTLRAASAGE--LYVVHIAAGDGAAAP-MRDLLRVQHRTLGGLR 1070 +IV LP SDADE +L LRAA+AG+ L ++H AA +G A P MR LLR+QHR L G R Sbjct: 1009 RIVGLPASDADEERLEAELRAAAAGDSTLRILHCAALEGDATPSMRSLLRMQHRVLNGTR 1068 Query: 1071 RLFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGL 1126 RLFRAA AELR+P+WL TR QRVTD D+V P QSCLWGFGRAA+LE P +WGGL Sbjct: 1069 RLFRAAAAAELRAPVWLTTRGAQRVTDADSVSPAQSCLWGFGRAASLEHPQLWGGL 1124 Score = 1020 bits (2637), Expect = 0.0 Identities = 512/884 (57%), Positives = 630/884 (71%), Gaps = 7/884 (0%) Query: 1563 AVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRXXXX 1622 A+V + R PGA D FW++L G DA+ EVP +RW++D+F+D D D GK +R Sbjct: 15 AIVGYAARVPGAADAAEFWDVLRHGRDAVSEVPGERWNVDDFFDSDADAAGKIVSRRAGF 74 Query: 1623 XXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAA 1682 FFG+S RE + ++PQ RL+LET W+ +E G AP+ L + TGVF G++ Sbjct: 75 VDDVAGFDAPFFGVSAREVMLMDPQHRLLLETAWQAVEHWGTAPTALANTNTGVFVGLST 134 Query: 1683 NEYAHLLSAE-SIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQA 1741 ++Y ++S E S D+I+ + G A A +GR+++ LG +GPAV VDTACSS+LVAVHQA Sbjct: 135 HDYLSMVSDELSYDEIDAYMAIGTAAAAAAGRISYRLGLQGPAVTVDTACSSSLVAVHQA 194 Query: 1742 CQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVL 1801 CQAL+ G+CD+ALAGG NVLLSP T++ SRA ML+P GRCKTFDA+ADGYVR EGCGV+ Sbjct: 195 CQALRLGECDVALAGGANVLLSPATMITFSRAHMLAPDGRCKTFDAAADGYVRGEGCGVI 254 Query: 1802 VLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVD 1861 VLKRL DA+RDGDR+ AVI S+VNQDGAS GLTVPNG AQQR+I L RAG+S DV Sbjct: 255 VLKRLDDAIRDGDRIRAVIRGSAVNQDGASGGLTVPNGVAQQRVIAEALERAGVSAHDVG 314 Query: 1862 YLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVL 1921 YLEAHGTGT LGDPIEVQ PLL+GSVKTNIGH E+A+G AG+IKVVL Sbjct: 315 YLEAHGTGTSLGDPIEVQAAAAVFGEGRDPDRPLLIGSVKTNIGHLEAAAGIAGIIKVVL 374 Query: 1922 SLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHVL 1981 SL+H LP+ L+F NPSP+IPWD L VRV+DE WQ NGR R AGVSSFGF+GTNAHV+ Sbjct: 375 SLEHEQLPKHLNFRNPSPYIPWDRLAVRVLDEATGWQRNGRPRVAGVSSFGFSGTNAHVI 434 Query: 1982 VEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGL 2041 +EEAP + D VL LSAR+P AL +LA RY DWL+A P Sbjct: 435 LEEAPQEARANAAGPRAVVEP----EDRRFSVLPLSARTPAALAQLADRYRDWLTAHPET 490 Query: 2042 DIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWL 2101 D++++C TAGVGR+HFE+RAALVV+S G++RGE RP TAWL Sbjct: 491 DLSELCFTAGVGRAHFEHRAALVVNSTESATELLGALADDRPAPGLLRGECDDRPKTAWL 550 Query: 2102 FTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHTS 2161 F GQGSQ+ GMARELF+T+PVFA+T+ +CA V +L +P+LDV+F D + D L+ TS Sbjct: 551 FPGQGSQFAGMARELFETEPVFAETMTRCAAVVDAVLEKPMLDVIF--DVDDPDTLRQTS 608 Query: 2162 FAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMF 2221 +AQPALFAVE+GLARLWQSW +EPDVVLGHSVGQYAAACVAGVFSL+DGA L+AERGR+F Sbjct: 609 YAQPALFAVELGLARLWQSWGLEPDVVLGHSVGQYAAACVAGVFSLEDGALLLAERGRLF 668 Query: 2222 GSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFEDEGI 2281 G+LP GGRMVA+FA AE VE EFPR+SV AYNG NTVL+GP EDL+ +V +G+ Sbjct: 669 GNLPAGGRMVAIFAAAERVESCTDEFPRLSVAAYNGANTVLAGPAEDLDRVVAALTSDGV 728 Query: 2282 RCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWR 2341 RC WL TSHAFHS LLDP LD P LVCNRTGA L LDA YWR Sbjct: 729 RCDWLDTSHAFHSALLDPALDEFEAYAGRFGFRSPQRTLVCNRTGAALGRTAQLDASYWR 788 Query: 2342 RHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVAD 2401 RH+RQP++FA+SV T+A L C+VL+E+G QPVLT AA++ WP+ APRA+ASLR+ AD Sbjct: 789 RHARQPIEFAKSVATLADLNCAVLLEVGAQPVLTAAALRAWPDPATAPRAIASLRRNGAD 848 Query: 2402 RRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFW 2445 RQIA+AL AY+ GH P F A+ P R ++LPTYPFQ R +W Sbjct: 849 HRQIAEALGGAYICGHLPAFGALQHGPTRKLDLPTYPFQHRHYW 892 >tr|Q68BG4|Q68BG4_STRHA Tax_Id=1944 (hlsB)SubName: Full=Type I polyketide synthase;[Streptomyces halstedii] Length = 7111 Score = 1551 bits (4017), Expect = 0.0 Identities = 1068/3024 (35%), Positives = 1514/3024 (50%), Gaps = 186/3024 (6%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 A++G A RFPG S E+ W + DGR+ IS P +R WD++ + PDP PG Sbjct: 37 AVVGMACRFPGGVNSPEQLWDFVLDGRDGISGFPTERGWDLDSLYHPDPDHPGTSYASEG 96 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FD FFG+S RE M+PQ R+L++T+W A+E++GI P SL S TGVFVG Sbjct: 97 GFLHDAGEFDPAFFGISPREALAMEPQQRLLLQTSWEAIENAGIDPLSLKGSRTGVFVGA 156 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 +Y D +E Y+ GT+N+ +GR++Y LG +GPA+ VDTACSSSLVA+H Sbjct: 157 INQEYGPRLYDAAPDDNVEGYLLTGTANSVVSGRVAYVLGTEGPALTVDTACSSSLVALH 216 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A QALR +EC +AL GG V+ TP + FS LA DGRCK+F AAADG EG G Sbjct: 217 LAGQALRQDECSMALVGGVTVMTTPTGFVEFSRQRGLAADGRCKSFAAAADGTGWAEGVG 276 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V+VV+RL DA R G + AVIR SA+NQDGAS GLT PNG +QQRVI AL A L AD Sbjct: 277 VLVVERLSDAQRLGHPVLAVIRSSAVNQDGASNGLTAPNGPSQQRVIRQALAAADLSSAD 336 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT+LGDPIEAQA G R + PL +GS K+NIGH + Sbjct: 337 VDVVEAHGTGTALGDPIEAQALLATYGQNRPEDRPLRLGSIKSNIGHTQAAAGVAGVIKM 396 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 L + LP L+ + P+PH+ W +E++ +T W +P A VSSFG +GTNAH Sbjct: 397 VMALRHGVLPATLHVDGPTPHVDWTSGAVELLADTTVWPEVDRPWRAAVSSFGISGTNAH 456 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVS 492 I+E+AP V A EP +S R +AL A R+W+ HP+ RL DV Sbjct: 457 TIIEQAPPVEVGA-PEPAVKGNVLVPWVVSGRGADALRAQAARLREWVLEHPEHRLVDVG 515 Query: 493 HTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEA-PKTAWLFTGQG 551 H+ +R+ E R ++ + R++ ++ L A A P PG+V G S A A+LFTGQG Sbjct: 516 HSLVVSRSAFEDRVVVLGSDRDALLDGLAAAAQGEPGPGVVVGSSAGAGGGVAFLFTGQG 575 Query: 552 SQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYA 611 +Q GM EL PVFA + + + LE+PL +V+F E D + + L T + Sbjct: 576 AQRLGMGHELAARFPVFASALDEVCVQLDAHLERPLREVLF--AEPDTEAAALLDETVFT 633 Query: 612 QPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGS 671 Q ALFAVE+ L RL +SW PD ++GHSVG +AA VAGV +ED A ++ RGRL + Sbjct: 634 QAALFAVEVALYRLVESWSLTPDYLLGHSVGGLAAAHVAGVLSLEDAAEVVVARGRLMQA 693 Query: 672 LPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVA-TLVADGVR 730 LP GG M ++ + + E L +S+AA NG V+ +D +AVA A G + Sbjct: 694 LPKGGAMVSLQASED--EVLESLSGLVSIAAVNGPQAVVISGDEDAVTAVAEEWRARGRK 751 Query: 731 CDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRR 790 L SHAFHSAL++P+L FE ++ P+ +I + TG L AYW Sbjct: 752 VKRLTVSHAFHSALMEPMLATFEQVLSRVTLNAPRIPVISDSTGLPLTPEQATSPAYWTG 811 Query: 791 HARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTA---TALAAWPDPATTPQVLASLRPTT 847 H R PV F ++V L + LE+GP VL+A T++ + TP LR Sbjct: 812 HVRNPVLFHQAVTHLTEQGVSAFLELGPDGVLSAMTRTSVVGRDNTVVTP----LLRADR 867 Query: 848 ADHRQITEAVAAAYAAGHLPDFRAFRQ-PDARKLDLPTYPFEHRQFWFSDNRAIDRDTQT 906 + A+A Y G DFRA ++ AR + LPTY F H+ FW + T+ Sbjct: 868 DEPYSALTALAELYVNGTHVDFRAVQEGTGARLVTLPTYAFRHQWFW------LPTGTRP 921 Query: 907 ASAGSVTPHRTQAVRLLEDGQIEELAAL---IDGETVDEQTLRVLNKLAARHNQQRSTHV 963 A+ P ++E G ELA + + E E+ ++L L + Q + Sbjct: 922 ATGLDDDPF----WGMVERGDAAELATIFAELGAEASAEEWGQLLPALTSWRQAQHARST 977 Query: 964 DPDARYEIRWDXXXXXXXXXXXXXDWILVG----DDTAAVLEFADALTAGGHRHQIVALP 1019 RY I W W+++ D+TA E A AL G V L Sbjct: 978 TDSWRYRITW-KPRTGAPTTALSGTWLVITPTGYDETAT--ECAAALRRHGAAVIPVTLD 1034 Query: 1020 GSDADEAQ-----LVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFR 1074 S ++ + ++ AA G L V G AA D + G L + Sbjct: 1035 ASTSETDRHAWHTRLEAEAAAMDGRLSGVVSLLGLAEAA--SDTSPAVPHGVAGTLALVQ 1092 Query: 1075 AANDAELRSPIWLVTRDGQRVTDTDTV-VPEQSCLWGFGRAAALELPHIWGGLADLSGA- 1132 A DA +++P+W +TR D + P Q+ +WGFG+ LE P WGGLADL Sbjct: 1093 ALGDARIQAPLWCLTRGAVSTGRPDPLRSPLQAMIWGFGQVVGLEHPARWGGLADLPETV 1152 Query: 1133 -DTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEP-SDTPLPVR-EDRTYLVTG 1189 D W +L + + EDQ+A+R + RLV P T R T L+TG Sbjct: 1153 DDHGWDQLCSALAD--GAEDQVAVRPAGLLVRRLVPAAPAPVVATGADARAAGGTVLITG 1210 Query: 1190 GLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHD 1249 G GA+G +A + A GA ++L SR E C ++ D+AD Sbjct: 1211 GTGALGGSIARWAAERGAQRLLLLSRSGDRAPGAEALLTELEAAGCPAEIVGCDIADRDA 1270 Query: 1250 VARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLR 1309 +A ++ + AE PL+ ++H AG + + L + V A K GA +L E DL Sbjct: 1271 LAAVLAAIPAE-HPLSAVIHTAGVLDDGVIDSLTPDRMATVLAAKHTGANNLHELTADL- 1328 Query: 1310 TDLDFFVSTSSIASVWGGF-GQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-AGMA 1367 L FV SS A+ WGG GQ +Y AANA+LD LA R+ G+ A S+ +GPWA GMA Sbjct: 1329 -PLSAFVLFSSAAATWGGVGGQGSYAAANAYLDALAEHRRDLGLPASSIAWGPWADGGMA 1387 Query: 1368 DAESRAR-LEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDWSRFLPLYQQAGRRAFL 1425 A R L++RG++ + P A ++ V+ G +A + W RF PL A + L Sbjct: 1388 AAGDLGRALDRRGLQPMRPESATGLLSRVLDRGDTTVTIADVAWERFYPLLATARPKPLL 1447 Query: 1426 SELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR-NAVAEVTRVDAD 1484 ++ L +L P + R L+ +R +A A + + Sbjct: 1448 HDIPQ----IAALLAETGADTLPSELGSRLAGLPDEDRSRLVLEAVRSHAAAVLGHANTA 1503 Query: 1485 EIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGE 1544 + F +LG DSL A+E R+ + G+ +P TLV D+P AD++L E+ G Sbjct: 1504 GVEPNRAFRELGFDSLTAIEFCNRLIRTTGRPLPPTLVFDYPTPLAVADFILGELTGTDP 1563 Query: 1545 QTNVRQASTV-TARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDI 1601 ++ TV TA D+P+A+V ++CR PG PE W L+A G DA+ P DR WDI Sbjct: 1564 AGTPHRSDTVATASPDEPLAIVGMACRLPGGIRTPEQLWRLVAEGGDAVSGFPTDRGWDI 1623 Query: 1602 DEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLER 1661 + Y PDPD PG +Y FFGISPREA+ ++PQQRL+LET WE +E Sbjct: 1624 ESLYHPDPDHPGTSYANEGGFLHEAGEFDAGFFGISPREALAMDPQQRLLLETSWEAIES 1683 Query: 1662 AGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFE 1721 AG P L+GS TGVFTG++ ++YA ++ + + +E + TGNA + +SGRVA+ LG E Sbjct: 1684 AGIDPLSLKGSSTGVFTGMSYHDYASPMTPVA-EGLEGYLGTGNAGSVVSGRVAYVLGTE 1742 Query: 1722 GPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGR 1781 GPAV VDTACSS+LVA+H A QAL+ G+C +ALAGGV V+ +P V SR R L+P GR Sbjct: 1743 GPAVTVDTACSSSLVALHWAAQALRQGECSMALAGGVTVMATPGMFVEFSRQRGLAPDGR 1802 Query: 1782 CKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGA 1841 CK F A ADG +EG G+++++RLSDA R G + AV+ +S+VNQDGAS+GLT PNG + Sbjct: 1803 CKAFAAGADGTGWAEGVGMVLVERLSDAQRLGHSILAVVRSSAVNQDGASNGLTAPNGPS 1862 Query: 1842 QQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVK 1901 QQR+I L+ AGL+ ADVD +EAHGTGT LGDPIE Q PLL+GS+K Sbjct: 1863 QQRVIRQALSTAGLTTADVDAVEAHGTGTNLGDPIEAQALLATYGQDRPEGRPLLLGSLK 1922 Query: 1902 TNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNG 1961 +NIGHT++A+G AG+IK+V++L+HGVLP +LH + PSPH+ W + V ++ E W G Sbjct: 1923 SNIGHTQAAAGVAGVIKMVMALRHGVLPATLHVDEPSPHVDWASGAVELLTEATAWPETG 1982 Query: 1962 RVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSP 2021 R RRA VSSFG +GTNAH ++E+AP T P +S R Sbjct: 1983 RPRRAAVSSFGISGTNAHTILEQAP-------AVSSGETDVPSRETGAEPTAWVISGRGK 2035 Query: 2022 EALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXX 2081 E L+ A R DW + P D+ + RS R ++ Sbjct: 2036 EGLIRQAARLRDWANEQPEHSATDIGFSLLSSRSLHRDRLVVLGSDRQVLVDGLAAFVEG 2095 Query: 2082 XTPAGVVRGE--HVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLP 2139 GVV G V ++F GQGSQ+ GM REL+ + PVF + +CA A+ ++ Sbjct: 2096 APWPGVVGGSGGGVVADRPVFVFPGQGSQWVGMGRELYASSPVFRARLDECAAALDPLVD 2155 Query: 2140 RPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAA 2199 L+DV+ A L+ QP L+AV + LA +W+SW + P V+GHS G+ AAA Sbjct: 2156 WSLIDVV--RGESGAPGLERVDVVQPVLWAVMVSLAAVWESWGVTPAAVVGHSQGEIAAA 2213 Query: 2200 CVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPN 2259 CVAG S++D A+++A R R + G MV+V A E + G+ VS+ A NGP+ Sbjct: 2214 CVAGALSVEDAAQVVALRSRAVRGMAGDGAMVSVALPAAEAEALTGD--GVSLAAVNGPS 2271 Query: 2260 T-VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTL 2318 + VLSG L +VE +G+R W+ +A HS +D + D + Sbjct: 2272 SVVLSGDRSALTPVVEGLTAQGVRTKWVPVDYASHSAHMDRIHDELLEILSGIEPKTSRI 2331 Query: 2319 PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAA 2378 PL + A + + +DA YW + R V+F E+V+ + G + +E+ P PVL + Sbjct: 2332 PLY-SAVSAEVIDTSRMDASYWFDNIRGTVRFHETVQALITDGLTAFVEVSPHPVLAMSV 2390 Query: 2379 VQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF---AAVHRQPRRPVELP 2435 + A ++ +LR+ + + A A +V G D+ A R P+R V+LP Sbjct: 2391 QDTLDQAEATGLSIGTLRRDENEHETLLTAAAELFVAGLPIDWNTAAYTGRSPQR-VDLP 2449 Query: 2436 TYPFQRRRFWPKASSI------AVDGGTAASGILGSGKDLASGD-TIYTSRLSVKSQPWL 2488 TY F R RFW +A+S + GT +LG+ +A GD T+ T ++S+++ PWL Sbjct: 2450 TYAFARERFWLRAASTTPTDARGLGLGTVGHPLLGAVVAMAEGDTTVLTGQISLRTHPWL 2509 Query: 2489 ADHVIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPAD 2545 ADH + G+V++PG + +A+ A V P +++++ P++L E + ++Q+ + PAD Sbjct: 2510 ADHAVLGSVLLPGTAFLELAIRAADHVDCP-QVEELILQAPLVLAEDRATDLQIQVGPAD 2568 Query: 2546 GGSVLSFQIHSRPYGE----RGADWSLNAEGTV-DTAGSDPDAAA-------DEQSDPVD 2593 G + + I+SRP+ E W+ +A GT+ T +D + D PV Sbjct: 2569 GDGIRAVDIYSRPHPEDEPAAQERWTHHASGTLAPTTRTDTEDTGLSVWPPHDATPLPVT 2628 Query: 2594 EVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQL--G 2651 ++ RL R L +GP + G L++ W E ++ + + G Sbjct: 2629 DIYPRLNR------------TGLEYGPLFQG-LRAAWRSGEEIYAEVALPDHQDDTAAPG 2675 Query: 2652 SEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHR 2711 +HP L+D +G +LP + L R R Sbjct: 2676 DYGVHPALLDAALHAIGFHLGDRATDTEGQG--WLPFSWTGAALHAVGASTL--RVRLTP 2731 Query: 2712 SALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPP 2771 D+ L D G + I T++ E LR G L+ L W P Sbjct: 2732 QGPDA----VSLLAADTTGAPVISIDSLTLRPVSAEQ-LRTRPGAGQNSLFALDWIPAGP 2786 Query: 2772 PPSADDAVGTWLI-------AGFDELAAKV-----------PG--CVPID-RNTDLQVLG 2810 + A G W I G E A PG VP D +N + VL Sbjct: 2787 VTGTEAATGPWAILDIAGIGGGETEALADALTVRGVPTEVHPGLEAVPADGQNAPVDVLL 2846 Query: 2811 EVLSQAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKLP 2870 VL+ A A ++ LL + Sbjct: 2847 PVLTTTAANEA---------------------------DALVSRLLGVLQEWLRRPEPTA 2879 Query: 2871 GGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXX 2929 L +VT +A ES + D AA+WG RT E P R + D +A+ Sbjct: 2880 SRLIVVTRGAIATESDADITDLAAAAVWGLIRTAQLEHPD---RFLLVDADQQALTDGSV 2936 Query: 2930 XXXXPGIQEPEIAVRQGKLLASRL 2953 G EP+ A+R G+LL RL Sbjct: 2937 VDAVRG-GEPQTAIRHGELLVPRL 2959 Score = 1118 bits (2893), Expect = 0.0 Identities = 929/2981 (31%), Positives = 1355/2981 (45%), Gaps = 284/2981 (9%) Query: 825 TALAAWPDPATTPQVLASLRP----TTADHRQITEAVAAAYAAGH-------LPDFRAFR 873 T L+ WP TP + + P T ++ + + + AA+ +G LPD + Sbjct: 2612 TGLSVWPPHDATPLPVTDIYPRLNRTGLEYGPLFQGLRAAWRSGEEIYAEVALPDHQ--- 2668 Query: 874 QPDARKLDLPTYPFE-----HRQFWFSDNRAIDRDTQ-------TASAGSVTPHRTQAVR 921 A D +P H + +RA D + Q T +A T VR Sbjct: 2669 DDTAAPGDYGVHPALLDAALHAIGFHLGDRATDTEGQGWLPFSWTGAALHAVGASTLRVR 2728 Query: 922 LLEDGQ--IEELAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRWDXXXXX 979 L G + LAA G V L ++A + R ++ + + W Sbjct: 2729 LTPQGPDAVSLLAADTTGAPVISIDSLTLRPVSAEQLRTRPG-AGQNSLFALDWIPAGPV 2787 Query: 980 XXXXXXXXDWILV------GDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLR 1033 W ++ G +T A+ ADALT G ++ PG +A A D Sbjct: 2788 TGTEAATGPWAILDIAGIGGGETEAL---ADALTVRGVPTEVH--PGLEAVPA---DGQN 2839 Query: 1034 AASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQ 1093 A L V+ A + A A + R LG L+ R R + +VTR G Sbjct: 2840 APVDVLLPVLTTTAANEADA-------LVSRLLGVLQEWLRRPEPTASR--LIVVTR-GA 2889 Query: 1094 RVTDTDTVVPE--QSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARITSPRDGED 1151 T++D + + + +WG R A LE P + L AD + + + + R GE Sbjct: 2890 IATESDADITDLAAAAVWGLIRTAQLEHPDRFL----LVDADQQALTDGSVVDAVRGGEP 2945 Query: 1152 QIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVV 1211 Q A+R + PRL R E + P + T L+TGG G +G +A +LA GA ++ Sbjct: 2946 QTAIRHGELLVPRLHRAMMEETGAPTEWATEGTVLITGGTGVLGAALARHLADRGARRLL 3005 Query: 1212 LTSRREPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAA 1271 L SR+ + D D +A L+ V + PL +VHAA Sbjct: 3006 LVSRQGARAAGSETLLADLRATGTLAEAVACDTTDRGALAELLAAVP-DAYPLTAVVHAA 3064 Query: 1272 GEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQT 1331 G + L L A + V A K AW+L + +L L FV SS +G GQ Sbjct: 3065 GVLDDAMLESLTPARIGAVLAPKATAAWNLHQLTAEL--PLSAFVLFSSATGTFGNAGQA 3122 Query: 1332 AYGAANAFLDGLAWRLRERGVTAVSVNFGPWA-----AGMADAESRARLEQRGVRTLSPA 1386 YGAANAFLD LA R G++A+S+ +G WA G + R R+ ++G L+ Sbjct: 3123 GYGAANAFLDALAQHRRAHGLSAISLGWGLWAEASAMTGHLAEQDRGRMHRKGADPLTTE 3182 Query: 1387 EALA--------------------GMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLS 1426 + LA G A PV ++ W + +A RA Sbjct: 3183 QGLALFDTATAQSRAHLLPVPLNTGALRDRAVPVTCPISSATWYGYRVAAPRAPARA--- 3239 Query: 1427 ELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLR-NAVAEVTRVDADE 1485 L +L P+ +R+ +R NA A + AD Sbjct: 3240 --------------------AGTGLAARLALLPLAERQRETLELVRANAAAVLGHAGADS 3279 Query: 1486 IRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGE- 1544 + E F +LG DSL +VELR R+ G +P TLV D+P A +LL + G+ Sbjct: 3280 VGAERAFRELGFDSLTSVELRNRLNAATGLRLPATLVFDYPTPLAIALHLLDSMFPDGDD 3339 Query: 1545 QTNVRQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDID 1602 +T A D+PIAVV ++CR+PG PE W+L+ G DAI +P DR WDI+ Sbjct: 3340 RTPSAPQQAALAAIDEPIAVVGMACRYPGGVTSPEQLWQLVTKGEDAISGLPLDRGWDIE 3399 Query: 1603 EFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERA 1662 + YDPDP PG +YTR FFGISPREA+ ++PQQRL+LET WE +E A Sbjct: 3400 KLYDPDPANPGTSYTRHGGFLHDAGEFDAGFFGISPREALAMDPQQRLLLETSWEAVESA 3459 Query: 1663 GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEG 1722 G P L+G+ TGVF GV ++YA L A S D + + TGNA + +SGR+A+A+G EG Sbjct: 3460 GIDPLSLKGTDTGVFAGVMYHDYATQLDAVSED-VGGYLGTGNASSVVSGRIAYAMGLEG 3518 Query: 1723 PAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC 1782 PA+ VDTACSS+LVA+H A AL+ G+C +ALAGGV V+ +P T V SR R L+ GRC Sbjct: 3519 PALTVDTACSSSLVALHLAAHALRQGECSMALAGGVTVMATPGTYVDLSRQRGLAVDGRC 3578 Query: 1783 KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQ 1842 K F A+ADG+ +EG GVLV++R+SDA R G + AV+ +S+VNQDGAS+GLT PNG +Q Sbjct: 3579 KAFAAAADGFGPAEGVGVLVVERISDAERLGHPILAVVRSSAVNQDGASNGLTAPNGPSQ 3638 Query: 1843 QRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKT 1902 QR+I LA A LS ADVD +EAHGTGT LGDPIE Q PL +GS+K+ Sbjct: 3639 QRVIRQALASAALSTADVDVVEAHGTGTALGDPIEAQALLATYGQGRPEGRPLRLGSLKS 3698 Query: 1903 NIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR 1962 NIGHT++A+G AG+IK+V++L+HGVLP +LH + PSPH+ W + V ++ E +PW GR Sbjct: 3699 NIGHTQAAAGVAGVIKMVMALRHGVLPATLHVDEPSPHVDWASGAVELLTEAMPWPEVGR 3758 Query: 1963 VRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPE 2022 RRA VSSFG +GTNAH++VE+AP T LS R Sbjct: 3759 PRRAAVSSFGISGTNAHIVVEQAPES--------QIEVAASREETPAGSVAWVLSGRGEG 3810 Query: 2023 ALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXX 2082 AL A R +WL P DV + RS FE R ++ Sbjct: 3811 ALRAQAARLREWLLERPEDRPVDVGFSLLSSRSVFEDRLVVLGSQREALLDGLAAAAEGA 3870 Query: 2083 TPAGVVRGE-HVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRP 2141 G+V+ V ++F GQGSQ+ GM REL+ + PVF + +CA A+ ++ Sbjct: 3871 PWPGLVQSSGDVSLSRAVFVFPGQGSQWVGMGRELYASSPVFRARLDECAAALDPLVEWS 3930 Query: 2142 LLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACV 2201 L+DV+ A L+ QP L+AV + LA +W+SW + P V+GHS G+ AAACV Sbjct: 3931 LIDVV--RGESGAPGLERVDVVQPVLWAVMVSLAAVWESWGVVPAAVVGHSQGEIAAACV 3988 Query: 2202 AGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNT- 2260 AG S+ D AR++A R R + G MV+V A E + G+ VS+ A NGP++ Sbjct: 3989 AGALSVVDAARVVALRSRAVRGMAGDGAMVSVALPAAEAEALTGD--GVSLAAVNGPSSV 4046 Query: 2261 VLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPL 2320 VLSG L +VE +G+R W+ +A HS ++ + D +PL Sbjct: 4047 VLSGDRSALTPVVEGLTAQGVRTKWVPVDYASHSAHMERIHDELLEILSGIEPKTSRIPL 4106 Query: 2321 VCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQ 2380 + A + +DA YW + R V+F E+V+T+ A G + +E+ P PVL + Sbjct: 4107 Y-STVSAARIDTSRMDASYWFDNIRGTVRFHETVQTLIADGLTAFVEVSPHPVLAMSVQD 4165 Query: 2381 VWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDF--AAVHRQPRRPVELPTYP 2438 + A ++ +LR+ + A A +V G D+ AA R V+LP Y Sbjct: 4166 TLDQAEANGLSIGTLRRDENEHETFLTAAAELFVAGLPIDWNTAAFTGMSARRVDLPAYA 4225 Query: 2439 FQRRRFW-PKASSIAVDG-----GTAASGILGSGKDLASGD-TIYTSRLSVKSQPWLADH 2491 FQRR +W AS A D G +LG+ +A D + T LS+++ PWLADH Sbjct: 4226 FQRRHYWLDTASQTAGDAQELGLGAVDHPLLGASVGVAESDLVVLTGHLSLRTHPWLADH 4285 Query: 2492 VIYGTVVVPGATYAAMALAA---VGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGS 2548 + G+V++PG + +A+ A VG RL+++ P++L + A R++Q+ + AD Sbjct: 4286 AVLGSVLLPGTAFLELAVRAGDQVGR-TRLEELVIQAPLLLADDA-RDLQVVVGAADETG 4343 Query: 2549 VLSFQIHSRPYGERGAD----WSLNAEGTVDTAGSDPDAAADEQSDPVDEVIERLERMRP 2604 + I+SRP+ + D W+ +A G + AG + AD D I + P Sbjct: 4344 RSTVDIYSRPHADGDLDSERAWTHHAGGIL--AGGPVEEFAD-----ADLSIWPPQNATP 4396 Query: 2605 QDLFETFADLELA---WGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMD 2661 D+ + ++ L+LA +GP + G L++ W E ++ + ++ +HP L+D Sbjct: 4397 LDIADFYSQLDLAGYEYGPAFRG-LRAAWRRGDEVFAEVELPESEQDRAAEFGLHPALLD 4455 Query: 2662 LCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVF 2721 + LP + V+L R R H + Sbjct: 4456 AALQAIGLTALGDSEPSEEAQPGKLPFSWNGVSLHASGAPMLRARLRPHGD------EAI 4509 Query: 2722 ELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSADDA-VG 2780 L D G + + + V RA L G L+ L W + P + +G Sbjct: 4510 SLVAADAHGEPVLSV-DSLVLRALDPQQLNGARTAVQEDLFALEWAPLGELPEQEAVELG 4568 Query: 2781 TWLIAGFDELAAKVPGCVP--IDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKXX 2838 W + L+ V G + + R + +V G V + G V+ G Sbjct: 4569 DWALLDVPGLSGSVDGLLGGLLGRGIEPRVCGSV-GELMVDGVEPDVVLLPVVGGG---- 4623 Query: 2839 XXXXXXXXXXXXXITNLLSAVHAAQGPSVKLPGG---LWIVTEHGVACESGEPVDPV-QA 2894 + +L V G L GG L +VT V+ SGE V V A Sbjct: 4624 -----GGGDAVDVVCGVLGVVREWLG----LVGGVSRLVVVTWGAVSVGSGEGVGDVGGA 4674 Query: 2895 ALWGFGRTTINEEPALHCRLVDCDGSSEAVDXXXXXXXXPGI--QEPEIAVRQGKLLASR 2952 +WG R+ +E P LVD +G V+ G+ E ++ VR G LL R Sbjct: 4675 GVWGLLRSAQSEHPGRFV-LVDVEG----VEGVGWGGLVDGVVCGEGQVVVRGGGLLVPR 4729 Query: 2953 LLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDE----------------- 2995 L+ R+G GG V+ T G + + V E Sbjct: 4730 LV---RAG------GGGLVIPETFTGGVSGVGSAGVGVESSGEVLGSSVGGVGSGWCVGV 4780 Query: 2996 -----------------------------------GYVQVR--VEAAGLNFRDVLNVLGL 3018 G +VR V AAG+NFRDVL LG+ Sbjct: 4781 GVGSGVGTLEGLGVVSAGAGAGVGVGVGSGVGGGLGVGEVRVAVRAAGVNFRDVLIGLGV 4840 Query: 3019 YPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGA 3078 YPG+ +G + AG V +G GV + +G RV G G F V A+ + +P G Sbjct: 4841 YPGE-ALLGSEGAGVVVGVGEGVVNVGVGDRVMGLFLGGFGPEVVVDARMVVRLPVGWSF 4899 Query: 3079 VEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTF 3137 VE AT+P LT D A ++ G+++L+HAA+GGVG+AA+Q+A+ G EVF TAS Sbjct: 4900 VEGATVPVVFLTAWYGLVDLAGVRAGERLLVHAAAGGVGMAAVQLARHWGVEVFGTASEG 4959 Query: 3138 KRSTLRRLGV--KYVYDSRTTDFADQI--LADTNGAGVDVVLNSLTSAGFVEATLKATAQ 3193 K LR LG+ ++ SR F ++ + NG GVDVVLNSL FV+ +L + Sbjct: 4960 KWEVLRGLGLDDAHIASSRDLGFVEKFGRGSSGNGGGVDVVLNSLVGE-FVDGSLGLLGE 5018 Query: 3194 GGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWT 3253 GGRF E+ K D+ + E + Y L + DRI+++L E+ G Sbjct: 5019 GGRFVEMGKLDVRDAGVVGELWSGVWYRNFDL---VEAGLDRIQEMLCELVGLFDVGVLE 5075 Query: 3254 PLPAEIYPITEARSAFRRMQQARHIGKIXXXXXXXXXXXXDRSYLITGGLGAIGLHTAAY 3313 LP + + E A R +QQARH+GK+ + +++GG G +G Y Sbjct: 5076 ALPVRCWDVREVVDALRFVQQARHVGKV---VLRVPGGWGSGTVVVSGGTGVLGRAVVRY 5132 Query: 3314 LAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAEL 3373 L G G ++L SR + E + A DVGD +A +L + E Sbjct: 5133 LVGCGVGRLLLLSRSGAAGEGVAGLVGELEGLGVVVDVVACDVGDREALAGVLGGVSGEF 5192 Query: 3374 PPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXXXXXXXXXXXXXXXXXX 3433 P+ G+ HLAGVLDD ++ + + + R A K G + Sbjct: 5193 -PVTGVVHLAGVLDDGMVESLSEGQVRRVFAGKVDGLVNLDVLTRGMPVEGFVVFSSAAG 5251 Query: 3434 XXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATAN---ITAQ 3490 GQ NYA ANA +D +VA+RR +GL + +G W + + + + Sbjct: 5252 VFGNAGQGNYAAANACVDAVVARRRVEGLPGVSLAWGLWSEASGMTGHLDAGDHDRMNRA 5311 Query: 3491 GLIPLDPSAALHALAEVIANGSGQATVLKANWQR--AAKVLGSARPPILDLVLP----SA 3544 GL L L +A Q ++ + R A +G P + LV +A Sbjct: 5312 GLAGFSTDHGLALLESALALPHAQLLPIRLDRARLQARADVGDVHPLLRGLVRSRSRRAA 5371 Query: 3545 AGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRL--ASPPAASSRFLDLGTDSL 3602 + G L +L+ + +R V + ++ L + A F +LG DSL Sbjct: 5372 SAVGIGVGGLGGRLVGLVEGERRRVVLDLVRSHAATVLGHGDVAGVGAGRAFRELGFDSL 5431 Query: 3603 MAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 A+ELRNRL++ G + + AT VFDYPT LA+YL+ Q+ Sbjct: 5432 TAVELRNRLNTATGVR--LPATLVFDYPTPTELADYLLVQM 5470 Score = 880 bits (2273), Expect = 0.0 Identities = 586/1570 (37%), Positives = 804/1570 (51%), Gaps = 73/1570 (4%) Query: 2 VSAEHPIEPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDP 59 VS+E P+ A++G A RFPG S E W + G + IS +P DR WD+ FDP Sbjct: 5486 VSSEEPL------AVVGMACRFPGGVGSPNELWDFVLAGGDGISGLPVDRGWDVAGLFDP 5539 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 DP G TR GF+ D FD FFG+S RE MDPQ R+L+ET+W AVE++GI P Sbjct: 5540 DPEREGTSYTREGGFLHDAAEFDPGFFGISPREALAMDPQQRLLLETSWEAVENAGIDPL 5599 Query: 120 SLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVA 179 SL ++TGVF G+ HD+ P+ + G+S + +GR++Y LGL+GPA+ Sbjct: 5600 SLKGTSTGVFAGVTYHDHALRLQSISGTPD--GLLGTGSSASVVSGRVAYVLGLEGPALT 5657 Query: 180 VDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFD 239 VDTACSSSLVA+H A QALR EC +ALAGG V+ TP T + FS LA DGRCK FD Sbjct: 5658 VDTACSSSLVALHLAGQALRQGECSMALAGGVTVMATPGTFVDFSRQRGLAADGRCKAFD 5717 Query: 240 AAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVI 299 +ADG+ EG G++V++RL DA R G + AVIRGSA+NQDGAS GLT PNG +QQRVI Sbjct: 5718 VSADGFGPAEGVGMLVLERLSDAQRLGHPVLAVIRGSAVNQDGASNGLTAPNGPSQQRVI 5777 Query: 300 ADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGH 359 AL AGL D+ +EAHGTGT+LGDPIEAQA G R + PL +GS K+NIGH Sbjct: 5778 RQALASAGLSTMDIDAVEAHGTGTALGDPIEAQALLATYGQDRPEDRPLRLGSIKSNIGH 5837 Query: 360 LEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIA 419 + +++ LP L+ P+PH+ W +E++ E W GKPR A Sbjct: 5838 TQAAAGVAGVIKMVLAMQHGVLPPTLHVNEPTPHVDWASGAVELLTEATAWPETGKPRRA 5897 Query: 420 GVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDW 479 VSSFG +GTNAH I+E+AP V A EP +S R +AL A R+W Sbjct: 5898 AVSSFGISGTNAHTIIEQAPQVEVGA-LEPAVKGDVLVPWVVSGRGADALRGQAARLREW 5956 Query: 480 LRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGES-H 538 HP+ RL DV H+ +R+ E RA ++ + RE+ ++ L A A P PG+V+G S Sbjct: 5957 ALKHPEERLIDVGHSLVMSRSAFEDRAVVLGSDREALLDGLAAAAQGEPWPGVVQGSSVG 6016 Query: 539 EAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELD 598 A+LFTGQG+Q GM REL PVFA + + + LE+PL +V+F E D Sbjct: 6017 SGGGVAFLFTGQGAQRVGMGRELSARFPVFASALDEVCVQLDAHLERPLREVLF--AEPD 6074 Query: 599 GDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDG 658 + + L T + Q ALFA+E+ L RL +SW PD ++GHS+G +AA V+GV +ED Sbjct: 6075 TEAAALLDETAFTQAALFAIEVALYRLVESWSLTPDYLLGHSIGGLAAAHVSGVLSLEDA 6134 Query: 659 ARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLE 718 A ++A RGRL +LP GG M ++ + + D +S+AA NG V+ +D Sbjct: 6135 AEVVAARGRLMQALPKGGAMVSLQASEDEVVESLD--GRVSIAAVNGPQAVVISGDEDAV 6192 Query: 719 SAVA-TLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSAL 777 +AVA A G + L SHAFHS L++P+L +FE ++ P+ +I + TG L Sbjct: 6193 TAVADEWRARGRKVKRLTVSHAFHSVLMEPMLAEFEQVLSRVTLNAPRIPVISDSTGLPL 6252 Query: 778 GRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTP 837 AYW H R PV F ++V L LE+GP VL+A + D + Sbjct: 6253 TVEQATSPAYWTGHVRNPVLFHQAVTHLTGQGVNSFLELGPDGVLSAMTRTSLADDSDI- 6311 Query: 838 QVLASLRPTTADHRQITEAVAAAYAAGHLPDFRA-FRQPDA-RKLDLPTYPFEHRQFWF- 894 V+ LR + A+A Y G + ++ A F +A R++DLPTY F+H +FW Sbjct: 6312 TVVPLLRRDREESEAALTALAELYVNGAVVEWSAVFGGGEAVRRVDLPTYAFQHERFWLE 6371 Query: 895 -SDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAA 953 D++A T AG +E G +E LA ++ + VL +L++ Sbjct: 6372 GGDSKASATVTDGLDAG--------FWGAVERGDVEGLAGVLGSGVSVDVWGEVLPELSS 6423 Query: 954 RHNQQRSTHVDPDARYEIRWDXXXXXXXXXXXXXD--WIL---VGDDTAAVLEFADALTA 1008 +R+ V RY + W W++ VG D V AL Sbjct: 6424 WWLGRRARSVVEGWRYRVEWRRVGGGLLSGGGGLSGTWVVVVPVGVDVGLVDGCVGALVG 6483 Query: 1009 GGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAAGD-GAAAPMRDLLRVQHRTLG 1067 G R V + G D V+ L + G L + GD + L+ LG Sbjct: 6484 CGVR---VVVVGVDVGVLGDVEGLGSLVVGGL-PEGVGVGDVSGVVSLLGLVEGWFEGLG 6539 Query: 1068 GLR-------RLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALEL 1119 G+ L R + +P+W VTR V D VV P Q +WG GR LE Sbjct: 6540 GVSLGVVGTLGLVRGLGGVGVVAPLWCVTRGAVGVGGGDVVVSPVQGLVWGLGRVVGLEH 6599 Query: 1120 PHIWGGLADL--SGADTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPL 1177 P WGG+ DL S W R + + + GEDQ+A+R V+ RLV P+ P+ Sbjct: 6600 PERWGGVVDLPVSVDGRGWERFCS-VLAGGGGEDQVAVRSSGVFVRRLV-----PAPVPV 6653 Query: 1178 PVR--------EDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXX 1229 V + +VTGG G +G VA +LA G G +VL SR Sbjct: 6654 AVSGGGWVGGLSGGSVVVTGGTGVLGGRVARWLAGCGVGRLVLVSRSGAAGVGVDGLVGE 6713 Query: 1230 XEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDR 1289 E V V+ DVAD +A ++ V+ E PL G+VHAAG G L GL E Sbjct: 6714 LEGLGVVVDVVACDVADREAMAGVLGGVSGEF-PLRGVVHAAGASGMGALEGLGVEEFAG 6772 Query: 1290 VFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRE 1349 V KV GA L E + + V SS A VWGG GQ AY AANAFLDGLA R Sbjct: 6773 VVGAKVGGAVVLDELVGGVP-----LVLFSSGAGVWGGGGQGAYSAANAFLDGLAEYRRG 6827 Query: 1350 RGVTAVSVNFGPWA-AGMADAESRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKI 1407 RG+ AVS+ +GPWA GM DA++ +LE+RG+ ++SP A+A M + +G VA + Sbjct: 6828 RGLPAVSIAWGPWADGGMVDAQAEQQLERRGLNSMSPELAIAAMEQAIESGDASLTVADV 6887 Query: 1408 DWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLI 1467 DW +F + A R L ++ L E+L +R + Sbjct: 6888 DWVKFYSAFASARPRPLLHDIPQVAEFLAETAAAENNTRQESGLAERLAGLSETERNRSV 6947 Query: 1468 TNYLRNAVAEVT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHP 1526 +R+ A V + + + E GF D+G DSL AVE R R+ + G +P TL+ D+P Sbjct: 6948 LELVRSHAAGVLGHANLEAVGSERGFLDIGFDSLTAVEFRNRVSKSTGLSLPPTLLFDYP 7007 Query: 1527 RLSDAADYLL 1536 + A +++ Sbjct: 7008 NAASLARHIV 7017 Score = 787 bits (2033), Expect = 0.0 Identities = 513/1317 (38%), Positives = 709/1317 (53%), Gaps = 57/1317 (4%) Query: 1184 TYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYACDVRVITAD 1243 T +V+GG G +G V YL G G ++L SR E V V+ D Sbjct: 5115 TVVVSGGTGVLGRAVVRYLVGCGVGRLLLLSRSGAAGEGVAGLVGELEGLGVVVDVVACD 5174 Query: 1244 VADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSE 1303 V D +A ++ V+ E P + G+VH AG + + L + +V RVFAGKV G +L Sbjct: 5175 VGDREALAGVLGGVSGEFP-VTGVVHLAGVLDDGMVESLSEGQVRRVFAGKVDGLVNLDV 5233 Query: 1304 ALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPW- 1362 + ++ FV SS A V+G GQ Y AANA +D + R R G+ VS+ +G W Sbjct: 5234 LTRGM--PVEGFVVFSSAAGVFGNAGQGNYAAANACVDAVVARRRVEGLPGVSLAWGLWS 5291 Query: 1363 -AAGMA---DAESRARLEQRGVRTLSPAEALAGMADVVAGP-VQGVVAKIDWSRFLPLYQ 1417 A+GM DA R+ + G+ S LA + +A P Q + ++D +R Q Sbjct: 5292 EASGMTGHLDAGDHDRMNRAGLAGFSTDHGLALLESALALPHAQLLPIRLDRARL----Q 5347 Query: 1418 QAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTKAPVQQRKSLITNYLRNAVAE 1477 + L L L +L +R+ ++ + +R+ A Sbjct: 5348 ARADVGDVHPLLRGLVRSRSRRAASAVGIGVGGLGGRLVGLVEGERRRVVLDLVRSHAAT 5407 Query: 1478 VT-RVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLL 1536 V D + F +LG DSL AVELR R+ G +P TLV D+P ++ ADYLL Sbjct: 5408 VLGHGDVAGVGAGRAFRELGFDSLTAVELRNRLNTATGVRLPATLVFDYPTPTELADYLL 5467 Query: 1537 VEVLGLGEQTNVRQASTVTARTDDPIAVVAVSCRFPGAP-DPESFWELLAGGVDAIREVP 1595 V+++G + Q ++ +++P+AVV ++CRFPG P W+ + G D I +P Sbjct: 5468 VQMVGESGAADSVQVP-ISVSSEEPLAVVGMACRFPGGVGSPNELWDFVLAGGDGISGLP 5526 Query: 1596 EDR-WDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLET 1654 DR WD+ +DPDP+ G +YTR P FFGISPREA+ ++PQQRL+LET Sbjct: 5527 VDRGWDVAGLFDPDPEREGTSYTREGGFLHDAAEFDPGFFGISPREALAMDPQQRLLLET 5586 Query: 1655 VWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFI-TGNALNAISGR 1713 WE +E AG P L+G+ TGVF GV ++ H L +SI + TG++ + +SGR Sbjct: 5587 SWEAVENAGIDPLSLKGTSTGVFAGVTYHD--HALRLQSISGTPDGLLGTGSSASVVSGR 5644 Query: 1714 VAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRA 1773 VA+ LG EGPA+ VDTACSS+LVA+H A QAL+ G+C +ALAGGV V+ +P T V SR Sbjct: 5645 VAYVLGLEGPALTVDTACSSSLVALHLAGQALRQGECSMALAGGVTVMATPGTFVDFSRQ 5704 Query: 1774 RMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSG 1833 R L+ GRCK FD SADG+ +EG G+LVL+RLSDA R G V AVI S+VNQDGAS+G Sbjct: 5705 RGLAADGRCKAFDVSADGFGPAEGVGMLVLERLSDAQRLGHPVLAVIRGSAVNQDGASNG 5764 Query: 1834 LTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXX 1893 LT PNG +QQR+I LA AGLS D+D +EAHGTGT LGDPIE Q Sbjct: 5765 LTAPNGPSQQRVIRQALASAGLSTMDIDAVEAHGTGTALGDPIEAQALLATYGQDRPEDR 5824 Query: 1894 PLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDE 1953 PL +GS+K+NIGHT++A+G AG+IK+VL++QHGVLP +LH P+PH+ W + V ++ E Sbjct: 5825 PLRLGSIKSNIGHTQAAAGVAGVIKMVLAMQHGVLPPTLHVNEPTPHVDWASGAVELLTE 5884 Query: 1954 PVPWQTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQV 2013 W G+ RRA VSSFG +GTNAH ++E+AP G P V Sbjct: 5885 ATAWPETGKPRRAAVSSFGISGTNAHTIIEQAP-------QVEVGALEPAVKGDVLVPWV 5937 Query: 2014 LALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXX 2073 +S R +AL A R +W P + DV H+ + RS FE RA ++ Sbjct: 5938 --VSGRGADALRGQAARLREWALKHPEERLIDVGHSLVMSRSAFEDRAVVLGSDREALLD 5995 Query: 2074 XXXXXXXXXTPAGVVRGEHV-HRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAE 2132 GVV+G V A+LFTGQG+Q GM REL PVFA + + Sbjct: 5996 GLAAAAQGEPWPGVVQGSSVGSGGGVAFLFTGQGAQRVGMGRELSARFPVFASALDEVCV 6055 Query: 2133 AVADMLPRPLLDVLFA-TDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGH 2191 + L RPL +VLFA D E A LL T+F Q ALFA+E+ L RL +SW++ PD +LGH Sbjct: 6056 QLDAHLERPLREVLFAEPDTEAAALLDETAFTQAALFAIEVALYRLVESWSLTPDYLLGH 6115 Query: 2192 SVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFA-DAEHVEQVAGEFPRV 2250 S+G AAA V+GV SL+D A ++A RGR+ +LP+GG MV++ A + E VE + G RV Sbjct: 6116 SIGGLAAAHVSGVLSLEDAAEVVAARGRLMQALPKGGAMVSLQASEDEVVESLDG---RV 6172 Query: 2251 SVGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXX 2309 S+ A NGP V+SG + + + + + G + L SHAFHS L++P+L Sbjct: 6173 SIAAVNGPQAVVISGDEDAVTAVADEWRARGRKVKRLTVSHAFHSVLMEPMLAEFEQVLS 6232 Query: 2310 XXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIG 2369 P +P++ + TG LT + YW H R PV F ++V + G + +E+G Sbjct: 6233 RVTLNAPRIPVISDSTGLPLTVEQATSPAYWTGHVRNPVLFHQAVTHLTGQGVNSFLELG 6292 Query: 2370 PQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVH--RQ 2427 P VL+ A + + V LR+ + ALA YV G +++AV + Sbjct: 6293 PDGVLS-AMTRTSLADDSDITVVPLLRRDREESEAALTALAELYVNGAVVEWSAVFGGGE 6351 Query: 2428 PRRPVELPTYPFQRRRFW-----PKASSIAVDGGTAA-------------SGILGSG 2466 R V+LPTY FQ RFW KAS+ DG A +G+LGSG Sbjct: 6352 AVRRVDLPTYAFQHERFWLEGGDSKASATVTDGLDAGFWGAVERGDVEGLAGVLGSG 6408 Score = 654 bits (1687), Expect = 0.0 Identities = 372/905 (41%), Positives = 509/905 (56%), Gaps = 18/905 (1%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 A++G A R+PG S E+ W L+ G +AIS +P DR WDIE+ +DPDP+ PG TR Sbjct: 3358 AVVGMACRYPGGVTSPEQLWQLVTKGEDAISGLPLDRGWDIEKLYDPDPANPGTSYTRHG 3417 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE MDPQ R+L+ET+W AVE +GI P SL ++TGVF G+ Sbjct: 3418 GFLHDAGEFDAGFFGISPREALAMDPQQRLLLETSWEAVESAGIDPLSLKGTDTGVFAGV 3477 Query: 133 ATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIH 192 HDY + ++ Y+ G +++ +GRI+Y +GL+GPA+ VDTACSSSLVA+H Sbjct: 3478 MYHDYATQL--DAVSEDVGGYLGTGNASSVVSGRIAYAMGLEGPALTVDTACSSSLVALH 3535 Query: 193 QACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG 252 A ALR EC +ALAGG V+ TP T + S LA DGRCK F AAADG+ EG G Sbjct: 3536 LAAHALRQGECSMALAGGVTVMATPGTYVDLSRQRGLAVDGRCKAFAAAADGFGPAEGVG 3595 Query: 253 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPAD 312 V+VV+R+ DA R G I AV+R SA+NQDGAS GLT PNG +QQRVI AL A L AD Sbjct: 3596 VLVVERISDAERLGHPILAVVRSSAVNQDGASNGLTAPNGPSQQRVIRQALASAALSTAD 3655 Query: 313 VGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXXXXXXX 372 V +EAHGTGT+LGDPIEAQA G GR PL +GS K+NIGH + Sbjct: 3656 VDVVEAHGTGTALGDPIEAQALLATYGQGRPEGRPLRLGSLKSNIGHTQAAAGVAGVIKM 3715 Query: 373 XXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSFGFAGTNAH 432 L + LP L+ + PSPH+ W +E++ E +PW G+PR A VSSFG +GTNAH Sbjct: 3716 VMALRHGVLPATLHVDEPSPHVDWASGAVELLTEAMPWPEVGRPRRAAVSSFGISGTNAH 3775 Query: 433 VILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVS 492 +++E+AP E P LS R AL A R+WL P+ R DV Sbjct: 3776 IVVEQAPESQIEVAASREETPAGSVAWVLSGRGEGALRAQAARLREWLLERPEDRPVDVG 3835 Query: 493 HTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESH-EAPKTAWLFTGQG 551 + ++R+ E R ++ + RE+ ++ L A A+ P PGLV+ + ++F GQG Sbjct: 3836 FSLLSSRSVFEDRLVVLGSQREALLDGLAAAAEGAPWPGLVQSSGDVSLSRAVFVFPGQG 3895 Query: 552 SQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESP-LRHTTY 610 SQ+ GM REL+ + PVF + +CA A+ ++E L+DV+ G++ +P L Sbjct: 3896 SQWVGMGRELYASSPVFRARLDECAAALDPLVEWSLIDVV------RGESGAPGLERVDV 3949 Query: 611 AQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFG 670 QP L+AV + LA +W+SWG P VVGHS G+ +AACVAG V D AR++A R R Sbjct: 3950 VQPVLWAVMVSLAAVWESWGVVPAAVVGHSQGEIAAACVAGALSVVDAARVVALRSRAVR 4009 Query: 671 SLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGPAKDLESAVATLVADGV 729 + G M +V AE LT + +S+AA NG ++ VLSG L V L A GV Sbjct: 4010 GMAGDGAMVSVALPAAEAEALTGD--GVSLAAVNGPSSVVLSGDRSALTPVVEGLTAQGV 4067 Query: 730 RCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWR 789 R W+ +A HSA ++ I D+ +E + RI + + +A ++R+D +YW Sbjct: 4068 RTKWVPVDYASHSAHMERIHDELLEILSGIE-PKTSRIPLYSTVSAARIDTSRMDASYWF 4126 Query: 790 RHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPTTAD 849 + R V F ++V+TL +E+ P PVL + + +LR + Sbjct: 4127 DNIRGTVRFHETVQTLIADGLTAFVEVSPHPVLAMSVQDTLDQAEANGLSIGTLRRDENE 4186 Query: 850 HRQITEAVAAAYAAGHLPDFR--AFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTA 907 H A A + AG D+ AF AR++DLP Y F+ R +W D Q Sbjct: 4187 HETFLTAAAELFVAGLPIDWNTAAFTGMSARRVDLPAYAFQRRHYWLDTASQTAGDAQEL 4246 Query: 908 SAGSV 912 G+V Sbjct: 4247 GLGAV 4251 Score = 647 bits (1670), Expect = 0.0 Identities = 390/900 (43%), Positives = 510/900 (56%), Gaps = 27/900 (3%) Query: 1557 RTDDPIAVVAVSCRFPGAPD-PESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGK 1614 R +P+AVV ++CRFPG + PE W+ + G D I P +R WD+D Y PDPD PG Sbjct: 31 RWAEPLAVVGMACRFPGGVNSPEQLWDFVLDGRDGISGFPTERGWDLDSLYHPDPDHPGT 90 Query: 1615 TYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRT 1674 +Y P FFGISPREA+ +EPQQRL+L+T WE +E AG P L+GSRT Sbjct: 91 SYASEGGFLHDAGEFDPAFFGISPREALAMEPQQRLLLQTSWEAIENAGIDPLSLKGSRT 150 Query: 1675 GVFTGVAANEYA-HLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSS 1733 GVF G EY L A D +E + +TG A + +SGRVA+ LG EGPA+ VDTACSS Sbjct: 151 GVFVGAINQEYGPRLYDAAPDDNVEGYLLTGTANSVVSGRVAYVLGTEGPALTVDTACSS 210 Query: 1734 ALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYV 1793 +LVA+H A QAL+ +C +AL GGV V+ +P V SR R L+ GRCK+F A+ADG Sbjct: 211 SLVALHLAGQALRQDECSMALVGGVTVMTTPTGFVEFSRQRGLAADGRCKSFAAAADGTG 270 Query: 1794 RSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARA 1853 +EG GVLV++RLSDA R G V AVI +S+VNQDGAS+GLT PNG +QQR+I LA A Sbjct: 271 WAEGVGVLVVERLSDAQRLGHPVLAVIRSSAVNQDGASNGLTAPNGPSQQRVIRQALAAA 330 Query: 1854 GLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLMGSVKTNIGHTESASGA 1913 LS ADVD +EAHGTGT LGDPIE Q PL +GS+K+NIGHT++A+G Sbjct: 331 DLSSADVDVVEAHGTGTALGDPIEAQALLATYGQNRPEDRPLRLGSIKSNIGHTQAAAGV 390 Query: 1914 AGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGF 1973 AG+IK+V++L+HGVLP +LH + P+PH+ W + V ++ + W R RA VSSFG Sbjct: 391 AGVIKMVMALRHGVLPATLHVDGPTPHVDWTSGAVELLADTTVWPEVDRPWRAAVSSFGI 450 Query: 1974 TGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALSARSPEALVELARRYDD 2033 +GTNAH ++E+APP G P V +S R +AL A R + Sbjct: 451 SGTNAHTIIEQAPP-------VEVGAPEPAVKGNVLVPWV--VSGRGADALRAQAARLRE 501 Query: 2034 WLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXXXXXXXTPAGVVRGEHV 2093 W+ P + DV H+ V RS FE R ++ GVV G Sbjct: 502 WVLEHPEHRLVDVGHSLVVSRSAFEDRVVVLGSDRDALLDGLAAAAQGEPGPGVVVGSSA 561 Query: 2094 HR-PTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFA-TDR 2151 A+LFTGQG+Q GM EL PVFA + + + L RPL +VLFA D Sbjct: 562 GAGGGVAFLFTGQGAQRLGMGHELAARFPVFASALDEVCVQLDAHLERPLREVLFAEPDT 621 Query: 2152 ETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGA 2211 E A LL T F Q ALFAVE+ L RL +SW++ PD +LGHSVG AAA VAGV SL+D A Sbjct: 622 EAAALLDETVFTQAALFAVEVALYRLVESWSLTPDYLLGHSVGGLAAAHVAGVLSLEDAA 681 Query: 2212 RLMAERGRMFGSLPEGGRMVAVFADAEHV-EQVAGEFPRVSVGAYNGPN-TVLSGPGEDL 2269 ++ RGR+ +LP+GG MV++ A + V E ++G VS+ A NGP V+SG + + Sbjct: 682 EVVVARGRLMQALPKGGAMVSLQASEDEVLESLSG---LVSIAAVNGPQAVVISGDEDAV 738 Query: 2270 EEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVL 2329 + E + G + L SHAFHS L++P+L P +P++ + TG L Sbjct: 739 TAVAEEWRARGRKVKRLTVSHAFHSALMEPMLATFEQVLSRVTLNAPRIPVISDSTGLPL 798 Query: 2330 TGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVL---TGAAVQVWPEHM 2386 T + YW H R PV F ++V + G S +E+GP VL T +V + Sbjct: 799 TPEQATSPAYWTGHVRNPVLFHQAVTHLTEQGVSAFLELGPDGVLSAMTRTSVVGRDNTV 858 Query: 2387 AAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFW 2445 P LR + ALA YV G DF AV R V LPTY F+ + FW Sbjct: 859 VTP----LLRADRDEPYSALTALAELYVNGTHVDFRAVQEGTGARLVTLPTYAFRHQWFW 914 Score = 645 bits (1665), Expect = 0.0 Identities = 379/948 (39%), Positives = 519/948 (54%), Gaps = 25/948 (2%) Query: 2 VSAEHPIEPTPSFAIIGYAARFPGA-ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDP 59 V+ P EP AI+G A R PG + E+ W L+ +G +A+S P DR WDIE + P Sbjct: 1573 VATASPDEP---LAIVGMACRLPGGIRTPEQLWRLVAEGGDAVSGFPTDRGWDIESLYHP 1629 Query: 60 DPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPT 119 DP PG GF+ + FDA FFG+S RE MDPQ R+L+ET+W A+E +GI P Sbjct: 1630 DPDHPGTSYANEGGFLHEAGEFDAGFFGISPREALAMDPQQRLLLETSWEAIESAGIDPL 1689 Query: 120 SLANSNTGVFVGLATHDYLGMASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAV 178 SL S+TGVF G++ HDY AS E +E Y+ G + + +GR++Y LG +GPAV Sbjct: 1690 SLKGSSTGVFTGMSYHDY---ASPMTPVAEGLEGYLGTGNAGSVVSGRVAYVLGTEGPAV 1746 Query: 179 AVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTF 238 VDTACSSSLVA+H A QALR EC +ALAGG V+ TP + FS LAPDGRCK F Sbjct: 1747 TVDTACSSSLVALHWAAQALRQGECSMALAGGVTVMATPGMFVEFSRQRGLAPDGRCKAF 1806 Query: 239 DAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRV 298 A ADG EG G+V+V+RL DA R G I AV+R SA+NQDGAS GLT PNG +QQRV Sbjct: 1807 AAGADGTGWAEGVGMVLVERLSDAQRLGHSILAVVRSSAVNQDGASNGLTAPNGPSQQRV 1866 Query: 299 IADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIG 358 I AL AGL ADV +EAHGTGT+LGDPIEAQA G R PLL+GS K+NIG Sbjct: 1867 IRQALSTAGLTTADVDAVEAHGTGTNLGDPIEAQALLATYGQDRPEGRPLLLGSLKSNIG 1926 Query: 359 HLEXXXXXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRI 418 H + L + LP L+ + PSPH+ W +E++ E W G+PR Sbjct: 1927 HTQAAAGVAGVIKMVMALRHGVLPATLHVDEPSPHVDWASGAVELLTEATAWPETGRPRR 1986 Query: 419 AGVSSFGFAGTNAHVILEEAPAVGTPATTEPV-EDPRRYSVLPLSARTPEALVRLAGEYR 477 A VSSFG +GTNAH ILE+APAV + T P E + +S R E L+R A R Sbjct: 1987 AAVSSFGISGTNAHTILEQAPAVSSGETDVPSRETGAEPTAWVISGRGKEGLIRQAARLR 2046 Query: 478 DWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGES 537 DW P+ D+ + ++R+ R ++ + R+ ++ L A + P PG+V G Sbjct: 2047 DWANEQPEHSATDIGFSLLSSRSLHRDRLVVLGSDRQVLVDGLAAFVEGAPWPGVVGGSG 2106 Query: 538 H--EAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD 595 A + ++F GQGSQ+ GM REL+ + PVF + +CA A+ +++ L+DV+ Sbjct: 2107 GGVVADRPVFVFPGQGSQWVGMGRELYASSPVFRARLDECAAALDPLVDWSLIDVV---- 2162 Query: 596 ELDGDTESP-LRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFD 654 G++ +P L QP L+AV + LA +W+SWG P VVGHS G+ +AACVAG Sbjct: 2163 --RGESGAPGLERVDVVQPVLWAVMVSLAAVWESWGVTPAAVVGHSQGEIAAACVAGALS 2220 Query: 655 VEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG-ANTVLSGP 713 VED A+++A R R + G M +V AE LT + +S+AA NG ++ VLSG Sbjct: 2221 VEDAAQVVALRSRAVRGMAGDGAMVSVALPAAEAEALTGD--GVSLAAVNGPSSVVLSGD 2278 Query: 714 AKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRT 773 L V L A GVR W+ +A HSA +D I D+ +E + RI + + Sbjct: 2279 RSALTPVVEGLTAQGVRTKWVPVDYASHSAHMDRIHDELLEILSGIE-PKTSRIPLYSAV 2337 Query: 774 GSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDP 833 + + ++R+D +YW + R V F ++V+ L +E+ P PVL + Sbjct: 2338 SAEVIDTSRMDASYWFDNIRGTVRFHETVQALITDGLTAFVEVSPHPVLAMSVQDTLDQA 2397 Query: 834 ATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFR--AFRQPDARKLDLPTYPFEHRQ 891 T + +LR +H + A A + AG D+ A+ +++DLPTY F + Sbjct: 2398 EATGLSIGTLRRDENEHETLLTAAAELFVAGLPIDWNTAAYTGRSPQRVDLPTYAFARER 2457 Query: 892 FWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGET 939 FW D + G+V AV + +G L I T Sbjct: 2458 FWLRAASTTPTDARGLGLGTVGHPLLGAVVAMAEGDTTVLTGQISLRT 2505 Score = 159 bits (402), Expect = 8e-36 Identities = 120/363 (33%), Positives = 169/363 (46%), Gaps = 12/363 (3%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG GA+G A + A+ GA ++L SR A+ E C D+ Sbjct: 1207 LITGGTGALGGSIARWAAERGAQRLLLLSRSGDRAPGAEALLTELEAAGCPAEIVGCDIA 1266 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASH-XXXX 3416 D +A +LA I AE PL+ + H AGVLDD ++ + P+R T LA K GA++ Sbjct: 1267 DRDALAAVLAAIPAE-HPLSAVIHTAGVLDDGVIDSLTPDRMATVLAAKHTGANNLHELT 1325 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQ +YA ANA LD L RR GL A+ I +GPW GG Sbjct: 1326 ADLPLSAFVLFSSAAATWGGVGGQGSYAAANAYLDALAEHRRDLGLPASSIAWGPWADGG 1385 Query: 3477 MASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPI 3536 MA++ + +GL P+ P +A L+ V+ G T+ W+R +L +ARP Sbjct: 1386 MAAAGDLGRALDRRGLQPMRPESATGLLSRVLDRGDTTVTIADVAWERFYPLLATARPKP 1445 Query: 3537 LDLVLPSAA------GEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAA 3590 L +P A G T SEL +L +P R+ V E ++ L A+ Sbjct: 1446 LLHDIPQIAALLAETGADTLPSELGSRLAGLPDEDRSRLVLEAVRSHAAAVLGHANTAGV 1505 Query: 3591 --SSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEA 3648 + F +LG DSL AIE NRL G + T VFDYPT +A++++G+L + Sbjct: 1506 EPNRAFRELGFDSLTAIEFCNRLIRTTGR--PLPPTLVFDYPTPLAVADFILGELTGTDP 1563 Query: 3649 PET 3651 T Sbjct: 1564 AGT 1566 Score = 145 bits (367), Expect = 9e-32 Identities = 112/365 (30%), Positives = 160/365 (43%), Gaps = 19/365 (5%) Query: 3296 SYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAAD 3355 S ++TGG G +G A +LA G G +VL SR + E + A D Sbjct: 6668 SVVVTGGTGVLGGRVARWLAGCGVGRLVLVSRSGAAGVGVDGLVGELEGLGVVVDVVACD 6727 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 V D +A +L + E P L G+ H AG L E F + K GA Sbjct: 6728 VADREAMAGVLGGVSGEFP-LRGVVHAAGASGMGALEGLGVEEFAGVVGAKVGGA---VV 6783 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQ Y+ ANA LDGL RR +GL A I +GPW G Sbjct: 6784 LDELVGGVPLVLFSSGAGVWGGGGQGAYSAANAFLDGLAEYRRGRGLPAVSIAWGPWADG 6843 Query: 3476 GMASSEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP- 3534 GM ++ A + +GL + P A+ A+ + I +G TV +W + SARP Sbjct: 6844 GMVDAQ-AEQQLERRGLNSMSPELAIAAMEQAIESGDASLTVADVDWVKFYSAFASARPR 6902 Query: 3535 PIL-------DLVLPSAAGE--ATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA 3585 P+L + + +AA E +S L ++L + +R V E ++ L A Sbjct: 6903 PLLHDIPQVAEFLAETAAAENNTRQESGLAERLAGLSETERNRSVLELVRSHAAGVLGHA 6962 Query: 3586 SPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL 3643 + A S FLD+G DSL A+E RNR+ G ++ T +FDYP LA ++VGQL Sbjct: 6963 NLEAVGSERGFLDIGFDSLTAVEFRNRVSKSTG--LSLPPTLLFDYPNAASLARHIVGQL 7020 Query: 3644 PDAEA 3648 ++A Sbjct: 7021 TSSDA 7025 Score = 124 bits (311), Expect = 3e-25 Identities = 108/363 (29%), Positives = 152/363 (41%), Gaps = 17/363 (4%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVG 3357 LITGG G +G A +LA GA ++L SR+ + + A D Sbjct: 2980 LITGGTGVLGAALARHLADRGARRLLLVSRQGARAAGSETLLADLRATGTLAEAVACDTT 3039 Query: 3358 DEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXXX 3417 D +A+LLA + + PL + H AGVLDDA+L + P R LAPKA A + Sbjct: 3040 DRGALAELLAAV-PDAYPLTAVVHAAGVLDDAMLESLTPARIGAVLAPKATAAWNLHQLT 3098 Query: 3418 XXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGM 3477 GQA Y ANA LD L RRA GL A + +G W + Sbjct: 3099 AELPLSAFVLFSSATGTFGNAGQAGYGAANAFLDALAQHRRAHGLSAISLGWGLWAEASA 3158 Query: 3478 AS---SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANW----QRAAKV-- 3528 + +E + +G PL L A + N RA V Sbjct: 3159 MTGHLAEQDRGRMHRKGADPLTTEQGLALFDTATAQSRAHLLPVPLNTGALRDRAVPVTC 3218 Query: 3529 -LGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 + SA + P A A G + L +L +P+ +R E ++ L A Sbjct: 3219 PISSATWYGYRVAAPRAPARAAG-TGLAARLALLPLAERQRETLELVRANAAAVLGHAGA 3277 Query: 3588 PA--ASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL-P 3644 + A F +LG DSL ++ELRNRL++ G + AT VFDYPT +A +L+ + P Sbjct: 3278 DSVGAERAFRELGFDSLTSVELRNRLNAATG--LRLPATLVFDYPTPLAIALHLLDSMFP 3335 Query: 3645 DAE 3647 D + Sbjct: 3336 DGD 3338 Score = 45.4 bits (106), Expect = 0.17 Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 27/177 (15%) Query: 2852 ITNLLSAVHAAQGPSVKLPGGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPAL 2910 + L+ V A ++ P LW +T V+ +P+ P+QA +WGFG+ E PA Sbjct: 1084 VAGTLALVQALGDARIQAP--LWCLTRGAVSTGRPDPLRSPLQAMIWGFGQVVGLEHPAR 1141 Query: 2911 HCRLVDCDGSSEAVDXXXXXXXXPGI---QEPEIAVRQGKLLASRLLPWA---------- 2957 L D E VD + E ++AVR LL RL+P A Sbjct: 1142 WGGLADL---PETVDDHGWDQLCSALADGAEDQVAVRPAGLLVRRLVPAAPAPVVATGAD 1198 Query: 2958 --RSGHLTLPRGGDFVLA------PTERGAIDNLRLTETDVPEPDEGYVQVRVEAAG 3006 +G L GG L ERGA L L+ + P + +EAAG Sbjct: 1199 ARAAGGTVLITGGTGALGGSIARWAAERGAQRLLLLSRSGDRAPGAEALLTELEAAG 1255 >tr|D0LQW0|D0LQW0_HALO1 Tax_Id=502025 SubName: Full=Acyl transferase;[Haliangium ochraceum] Length = 3449 Score = 1550 bits (4012), Expect = 0.0 Identities = 1077/3036 (35%), Positives = 1513/3036 (49%), Gaps = 181/3036 (5%) Query: 15 AIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRA 72 AI+G RFPG+ + E W +L DG++ +S P+DR W ++ +DPDP + GK T + Sbjct: 38 AIVGMGCRFPGSVRTPEALWRVLHDGQDLVSRFPEDRGWKVDSLYDPDPDSYGKSYTVQG 97 Query: 73 GFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGL 132 GF+ D FDA FFG+S RE +DPQ R+L+ET+W E +GIAP SL S TGVFVG+ Sbjct: 98 GFLHDADRFDAGFFGISPREALALDPQQRLLLETSWETFERAGIAPDSLQGSATGVFVGV 157 Query: 133 ATHDYLGM-------ASDELTYPE-IEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTAC 184 +DY A L PE +E YM + ++ +AA+GR+SY GLQGPAV +DTAC Sbjct: 158 MYNDYGTRLWSLQRDAGFVLHAPEDLEGYMGVSSAPSAASGRLSYSFGLQGPAVTLDTAC 217 Query: 185 SSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADG 244 SSSLVAIH A QALR EC LALAGG V+ TP ++FS L+PDGRCK F A ADG Sbjct: 218 SSSLVAIHLAAQALRRGECTLALAGGVTVMATPGGFVSFSRQRALSPDGRCKAFSADADG 277 Query: 245 YVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALK 304 GEG G+++++RL DA R+G I AV+RGSA+NQDG S GLT PNG AQQRVI AL Sbjct: 278 AGWGEGAGMLLLERLSDAKRNGHPILAVLRGSAVNQDGKSQGLTAPNGPAQQRVILQALD 337 Query: 305 RAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXX 364 A L P V +EAHGTGT LGDPIEAQA G PE P+ +GS K+N+GH + Sbjct: 338 NARLTPNQVDAVEAHGTGTKLGDPIEAQALLATYGQAHTPEAPVWLGSLKSNLGHTQAAA 397 Query: 365 XXXXXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAGVSSF 424 L+++ LP L+ +TPSPHI W +++V+ PWQ NG+PR AGVSSF Sbjct: 398 GVAGVMKMVLALQHQMLPATLHAQTPSPHIDWSSGTLQLVQSARPWQTNGQPRRAGVSSF 457 Query: 425 GFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLP--LSARTPEALVRLAGEYRDWLRA 482 G +GTNAH+ILEEAP + AT + + LP LS +T EAL A L+ Sbjct: 458 GVSGTNAHLILEEAP-LEQAATEQRAAATAPVAALPFLLSGKTEEALKAQAQRLHQHLQR 516 Query: 483 HPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPK 542 H A L DVS++ T RAH EQRAALV ++RE + L ALA+ AP LV K Sbjct: 517 HEDAALVDVSYSLATTRAHFEQRAALVASTREELLAALAALANGESAPSLVVAPRSADGK 576 Query: 543 TAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTE 602 ++F GQGSQ+ GM R L + F V C A A ++ L + L+G + Sbjct: 577 VVFVFPGQGSQWQGMGRALLRSSDAFRAEVEACEAAFAPYIDGSL------REALEGGSS 630 Query: 603 SPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLI 662 QP LF + + LA W+S G VVGHS G+ +AA VAG ++D A+++ Sbjct: 631 D---RVDVLQPVLFTMMVSLAAHWRSLGVVAAAVVGHSQGEVAAAYVAGALSLDDAAQIV 687 Query: 663 AERGRLFGSLPAGGRMAAV-FTAPERAERLTDEYPSLSVAAYNGAN-TVLSGPAKDLESA 720 A R R + G MAAV A + A L L++ A N ++++G L++ Sbjct: 688 ALRSRALRRVAGRGAMAAVELGAEQLATYLAPFEEQLAIGAVNSPRASLVAGQPAALDAL 747 Query: 721 VATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS 780 + L DGV +HA H L++P+ + Q + L TG+ L Sbjct: 748 LEKLAEDGVYTQKARGNHASHCRLVEPLAQELTDALQGIRPSTCAIPLYSTVTGTRL-EG 806 Query: 781 TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVL 840 LD YW ++ R PV F + L + +E+ P PVL+ + + QV+ Sbjct: 807 HELDADYWYQNLRAPVLFQSATERLLADGHDLFVELSPHPVLSLPLYETFDAREHSAQVV 866 Query: 841 ASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQP-DARKLDLPTYPFEHRQFWFSDNRA 899 SLR H ++ ++ + GH D+ AF P R + LPTY F++ +FW R Sbjct: 867 TSLRRGDGTHARMLLSLGELHNRGHKLDWHAFFAPWHPRTVPLPTYAFQYERFWLEGTRN 926 Query: 900 IDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQT-----LRVLNKLAAR 954 RD +AS+GS + R +E G + L L+ + +++ L +L A+ Sbjct: 927 QSRD--SASSGSA---ESSFWRSVEGGDADGLERLLKLQEAPQRSALDSLLPLLTNFRAQ 981 Query: 955 HNQQRSTHVDPDA-RYEIRWDXXXXXXXXXXXXXDWILVGDDTAAVLEFADA----LTAG 1009 QQR+T DA RY + W W+L+ + A +A + L AG Sbjct: 982 AGQQRAT----DAWRYRLVWKPVTIATHAELSGV-WLLIVPASQAADIWAQSLMRGLEAG 1036 Query: 1010 GHRHQIVALPGSDADEAQLVDTLRAASAGELY--------VVHIAAGDGAAAPMRDLLRV 1061 G + AD A+L LR AG+ V+ +AA D P L Sbjct: 1037 GGTVVTCHVHHDLADRAKLEARLRELLAGKALPSAQTIRGVISLAALDEGTCPAHPSL-- 1094 Query: 1062 QHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTDTDTVV-PEQSCLWGFGRAAALELP 1120 + L +A DA L+S +WL+TR + + + P Q+ WG GR LE P Sbjct: 1095 -SNGMALNFSLIQALLDAGLKSSVWLLTRGAVSIGPAERLTNPLQAMTWGTGRVLGLEHP 1153 Query: 1121 HIWGGLADLSGA--DTEWPRLIARITSPRDGEDQIALRGDAVYAPRLVRR---TGEPSDT 1175 WGGL DL A D RL+ + + + EDQ+ALRG YA RLVR E +DT Sbjct: 1154 DYWGGLIDLPEACSDGAVERLVGLLGACSE-EDQLALRGPGWYARRLVRAPLGAAEAADT 1212 Query: 1176 PLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPXXXXXXXXXXXXEQYAC 1235 +P T L+TGG G +G VA +LAS GA H+VL SRR + Sbjct: 1213 YVP---RGTVLITGGTGGLGAHVARWLASKGAQHLVLVSRRGELSPGAEQLHDELSELGA 1269 Query: 1236 DVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKV 1295 V + DVAD + +L+ + AE + +VHA G TPL + E V +GK Sbjct: 1270 RVTIAACDVADRAALHKLLDALDAEGASIRSVVHAGGVAQQTPLIAMTLREFAEVVSGKA 1329 Query: 1296 WGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAV 1355 GA L E LD FV SS +S WGG GQ AY A NAFLD LA R G A Sbjct: 1330 RGAQFLHERFD--AQPLDAFVLFSSGSSSWGGGGQGAYAAGNAFLDALAEHRRGLGRAAT 1387 Query: 1356 SVNFGPWAAG----MADAESRARLEQRGVRTLSPAEALAGMADVV-AGPVQGVVAKIDWS 1410 SV +G WA + D + L RG+ +SP A+A +A + + VA +DW+ Sbjct: 1388 SVAWGAWAGDGMVTLLDDSGESALRTRGILPMSPELAIAALAQALDHRETKLTVANMDWA 1447 Query: 1411 RFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXLVEQLTK-APVQQRKSLITN 1469 RF P + A R L +L L+ L K +R+ L++ Sbjct: 1448 RFAPAFASARSRPLLHDLAEAKGALEGAEGTSALEGRETELLAHLRKLTEPDRRRLLLSR 1507 Query: 1470 YLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLS 1529 L A + DA + + GFF++G+DSL+A+ELR+ ++ G +P T+ DHP Sbjct: 1508 VLEETAAVLGHADASRVEAKRGFFEMGLDSLLALELRKCLQSATGLKLPATIAFDHPSPE 1567 Query: 1530 DAADYL---LVEVLGLGEQT--NVRQASTVTARTDDPIAVVAVSCRFP-GAPDPESFWEL 1583 A +L L +LG + + AS +DPIA+V ++ +FP G DPE+FW L Sbjct: 1568 HVAAFLQQSLAPMLGDPKVVVDHAAHASPAVGEGNDPIAIVGMALQFPGGVDDPEAFWSL 1627 Query: 1584 LAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVW 1643 L G DA+ +P++RW+ D FYDPDP+ K+Y R FFGISPREA Sbjct: 1628 LERGGDAVAPIPKNRWNADAFYDPDPEAVNKSYVREAAMLTHIDLFDASFFGISPREAKS 1687 Query: 1644 IEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFIT 1703 I+PQ RL+LE W LE AG P+ L S+TGVF G+ +Y SI++ E + I Sbjct: 1688 IDPQHRLLLEASWHALEDAGIVPAALEDSQTGVFVGIRTGDYG--AGENSIEETEVYAIQ 1745 Query: 1704 GNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLS 1763 G + + +GR+AF LG GPA+AVDTACSS+LV +H AC+AL++G+C+LALA GVNV+ S Sbjct: 1746 GMSSSFAAGRLAFTLGLRGPALAVDTACSSSLVTLHLACKALRNGECELALAAGVNVMTS 1805 Query: 1764 PVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPAS 1823 P + SR R L+P GR K F A+ADGY R EG V+VL+RLS A +G RV AV+ S Sbjct: 1806 PSSFKLLSRTRSLAPDGRTKAFSANADGYGRGEGVIVVVLERLSRARAEGHRVMAVVRGS 1865 Query: 1824 SVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXX 1883 ++N DGASSG+TVPNG +QQ+++ A L AGL+ +D+D +E HGTGT LGDPIEVQ Sbjct: 1866 AINHDGASSGITVPNGSSQQQVLRAALEDAGLAPSDIDVVECHGTGTKLGDPIEVQAVGA 1925 Query: 1884 XXXXXXXXXXPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPW 1943 PLL+G VKTNIGH E+A+G AG+ K+VLSLQH LP +LH +P + W Sbjct: 1926 VYQEGRDPHSPLLLGGVKTNIGHLETAAGLAGVAKMVLSLQHEALPPTLHTTPLNPLLDW 1985 Query: 1944 DALPVRVIDEPVPW-QTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXX 2002 ++LP+RV+D PW + + R RRAGVS+FG +GTNAHV++EE P Sbjct: 1986 ESLPLRVVDRLEPWPREDARPRRAGVSAFGLSGTNAHVILEEPPAD------PAARTEAA 2039 Query: 2003 XXXGTDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAA 2062 ++ P LS +S AL + +L+A P L ++D+ ++ RSHF++R A Sbjct: 2040 NAAASEPPPWPFVLSGKSEPALRAQVEQLRAYLAAHPDLSLSDLAYSLATTRSHFDHRVA 2099 Query: 2063 LVVDSVXXXXXXXXXXXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPV 2122 +V PA + G ++F GQGSQ+ GMA L + V Sbjct: 2100 IVASDRTALIHQLAELGAGRAPADTLLGRRGADGKLTFVFPGQGSQWIGMAASLLTSSAV 2159 Query: 2123 FAQTVRQCAEAVADMLPRPLLDVLFATDRE-TADLLQHTSFAQPALFAVEMGLARLWQSW 2181 F V C A + + LL +L A + A L QPALF V + LA LW++ Sbjct: 2160 FRAQVEACEHAFSPYIDWSLLALLQAGPGDPDAARLDQIDVLQPALFTVMVSLAALWRAM 2219 Query: 2182 AIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVE 2241 +EPD V+GHS G+ AAA VAG+ SLD AR++A R R G+ G M AV +E Sbjct: 2220 GVEPDAVVGHSQGEVAAAHVAGILSLDVAARIVAVRSRALGAFTGRGSMAAVELPRGELE 2279 Query: 2242 QVAGEF---PRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELL 2297 Q+ R+SV A N P +T L+G ED++E+++ EGI L A H + + Sbjct: 2280 QLLATSALGERLSVAAVNSPCSTALAGAAEDIDELLQLLATEGIFALKLRADVASHCDQI 2339 Query: 2298 DPVLDXXXXXXXXXXXXXPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTV 2357 +P+ D +P TG L G L+A YW + RQPV F ++ + + Sbjct: 2340 EPLRDQLLSELGEFDPQPAQIPFYSTVTGKRLAG-PELNAAYWFDNLRQPVLFGDATQLL 2398 Query: 2358 AALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGH 2417 A G +E+ P PVL + + V SL + + ++ + GG Sbjct: 2399 LADGHRFFVEVSPHPVLAFSIHETLDAEEQTACVVGSLWQEEGYLARFLLSMVELHGGGF 2458 Query: 2418 RPDFAAVHRQP--RRPVELPTYPFQRRRFW-----PKASSIAVDG-GTAASGILGSGKDL 2469 D+ QP RPV LPTY FQ RFW + + +A G +A +LG+ L Sbjct: 2459 PVDWRTFF-QPTMARPVPLPTYRFQHERFWLEGTKAQHADVASAGLSSAEHPLLGAAVAL 2517 Query: 2470 A-SGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATY---AAMALAAVGTPARLKDVFFYE 2525 A SG + T+RL++ PWL H ++GTV++PG Y A +A VG R++++ Sbjct: 2518 ADSGGYLVTARLALAEHPWLVGHQVFGTVILPGTAYVEFATIAAHRVGL-ERVEELTLEA 2576 Query: 2526 PIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAA 2585 P+ L + + +QL+L P D + I+++P W+ +A GT+ AA Sbjct: 2577 PLALSAEGAVLLQLSLGPLDERGRRALTIYAQPEQAVEDGWTRHATGTL--------AAR 2628 Query: 2586 DEQSDPVDEVIER-----LERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI 2640 D +S +D E + L++ + L +GP + G L++++ E D+ Sbjct: 2629 DAESRALDFEFRTWPPVGAESLALDGLYDQLSAAGLQYGPAFQG-LRAVYRRGEEFFADV 2687 Query: 2641 LVGAELAEQLGSEPMHPVLMDLCTGVXXXXXXXXXXXEQGVNDLFLPLRYGQVTLAEKMP 2700 + A +HP L+D D+ LP + V+L + Sbjct: 2688 ELEQVFARDARRFALHPALLDAALHALTFQAI------HAATDVSLPFSWNDVSL--RSV 2739 Query: 2701 RRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRL 2760 R R RSA S V + D G + + E + E L R + Sbjct: 2740 GASALRVRLRRSASGSGISV---DIADTAGEPVAHVGELATRPVAPEQLHR--ASERQDG 2794 Query: 2761 LYTLGWHEVPPPPSADDAVGT--WLIAGFDELA----AKVPGCVPIDRNTDLQVLGEVLS 2814 L + W + P S++ V W + G ++ + A G V + + DL L E + Sbjct: 2795 LLRVDWSD-PRAFSSEARVPAQEWALVGPEDASLISHANATG-VSLTHHQDLNALLESIE 2852 Query: 2815 QAHARGAGFSGVVWRCATPGRKXXXXXXXXXXXXXXXITNLLSAVHAAQGPSVKL----- 2869 RG F VV + +++ A H+ ++ + Sbjct: 2853 ----RGGAFPEVV---------------VVPSYDVAPLRDVIDAAHSTAAHTLGVLQTWL 2893 Query: 2870 ------PGGLWIVTEHGVACESGEPV-DPVQAALWGFGRTTINEEPALHCRLVDCDG--- 2919 L +VT +A E V QA+LWG R +E P LVD D Sbjct: 2894 AEERFATARLIVVTRGAIATRPDEDVLGLAQASLWGLVRVAQSEHPDASLTLVDVDNRED 2953 Query: 2920 SSEAVDXXXXXXXXPG--IQEPEIAVRQGKLLASRL 2953 S A+ P EP++AVR G + RL Sbjct: 2954 SLHALFGLFGSRTAPNALAAEPQLAVRAGNVSVPRL 2989 Score = 631 bits (1627), Expect = e-178 Identities = 376/929 (40%), Positives = 513/929 (55%), Gaps = 18/929 (1%) Query: 9 EPTPSFAIIGYAARFPGAA-SAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKV 67 E AI+G A +FPG E +W+LL G +A++ +PK+RW+ + F+DPDP K Sbjct: 1600 EGNDPIAIVGMALQFPGGVDDPEAFWSLLERGGDAVAPIPKNRWNADAFYDPDPEAVNKS 1659 Query: 68 VTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTG 127 R A + + FDA FFG+S RE + +DPQHR+L+E +W A+E +GI P +L +S TG Sbjct: 1660 YVREAAMLTHIDLFDASFFGISPREAKSIDPQHRLLLEASWHALEDAGIVPAALEDSQTG 1719 Query: 128 VFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSS 187 VFVG+ T DY + E + E E Y G S++ AAGR+++ LGL+GPA+AVDTACSSS Sbjct: 1720 VFVGIRTGDY---GAGENSIEETEVYAIQGMSSSFAAGRLAFTLGLRGPALAVDTACSSS 1776 Query: 188 LVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVR 247 LV +H AC+ALR EC+LALA G NV+ +P++ S LAPDGR K F A ADGY R Sbjct: 1777 LVTLHLACKALRNGECELALAAGVNVMTSPSSFKLLSRTRSLAPDGRTKAFSANADGYGR 1836 Query: 248 GEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAG 307 GEG VVV++RL A +G R+ AV+RGSAIN DGAS G+TVPNG +QQ+V+ AL+ AG Sbjct: 1837 GEGVIVVVLERLSRARAEGHRVMAVVRGSAINHDGASSGITVPNGSSQQQVLRAALEDAG 1896 Query: 308 LRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHLEXXXXXX 367 L P+D+ +E HGTGT LGDPIE QA G V GR P PLL+G KTNIGHLE Sbjct: 1897 LAPSDIDVVECHGTGTKLGDPIEVQAVGAVYQEGRDPHSPLLLGGVKTNIGHLETAAGLA 1956 Query: 368 XXXXXXXXLENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR-NGKPRIAGVSSFGF 426 L++E LP L+ +P + WE LP+ VV PW R + +PR AGVS+FG Sbjct: 1957 GVAKMVLSLQHEALPPTLHTTPLNPLLDWESLPLRVVDRLEPWPREDARPRRAGVSAFGL 2016 Query: 427 AGTNAHVILEEA---PAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWLRAH 483 +GTNAHVILEE PA T A +P + + LS ++ AL + R +L AH Sbjct: 2017 SGTNAHVILEEPPADPAARTEAANAAASEPPPWPFV-LSGKSEPALRAQVEQLRAYLAAH 2075 Query: 484 PQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKT 543 P L+D++++ T R+H + R A+V + R + I L L R + G K Sbjct: 2076 PDLSLSDLAYSLATTRSHFDHRVAIVASDRTALIHQLAELGAGRAPADTLLGRRGADGKL 2135 Query: 544 AWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTES 603 ++F GQGSQ+ GMA L + VF V C A + ++ LL + A D D + Sbjct: 2136 TFVFPGQGSQWIGMAASLLTSSAVFRAQVEACEHAFSPYIDWSLL-ALLQAGPGDPDA-A 2193 Query: 604 PLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIA 663 L QPALF V + LA LW++ G EPD VVGHS G+ +AA VAG+ ++ AR++A Sbjct: 2194 RLDQIDVLQPALFTVMVSLAALWRAMGVEPDAVVGHSQGEVAAAHVAGILSLDVAARIVA 2253 Query: 664 ERGRLFGSLPAGGRMAAVFTAPERAERLTDEY---PSLSVAAYNG-ANTVLSGPAKDLES 719 R R G+ G MAAV E+L LSVAA N +T L+G A+D++ Sbjct: 2254 VRSRALGAFTGRGSMAAVELPRGELEQLLATSALGERLSVAAVNSPCSTALAGAAEDIDE 2313 Query: 720 AVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGR 779 + L +G+ L A H ++P+ D S + + + Q TG L Sbjct: 2314 LLQLLATEGIFALKLRADVASHCDQIEPLRDQLLSELGEFDPQPAQIPFYSTVTGKRLA- 2372 Query: 780 STRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQV 839 L+ AYW + RQPV F + + L R +E+ P PVL + T V Sbjct: 2373 GPELNAAYWFDNLRQPVLFGDATQLLLADGHRFFVEVSPHPVLAFSIHETLDAEEQTACV 2432 Query: 840 LASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPD-ARKLDLPTYPFEHRQFWFSDNR 898 + SL + ++ + G D+R F QP AR + LPTY F+H +FW + Sbjct: 2433 VGSLWQEEGYLARFLLSMVELHGGGFPVDWRTFFQPTMARPVPLPTYRFQHERFWLEGTK 2492 Query: 899 AIDRDTQTASAGSVT-PHRTQAVRLLEDG 926 A D +A S P AV L + G Sbjct: 2493 AQHADVASAGLSSAEHPLLGAAVALADSG 2521 Score = 607 bits (1564), Expect = e-170 Identities = 363/947 (38%), Positives = 514/947 (54%), Gaps = 29/947 (3%) Query: 1549 RQASTVTARTDDPIAVVAVSCRFPGA-PDPESFWELLAGGVDAIREVPEDR-WDIDEFYD 1606 +Q +TART +PIA+V + CRFPG+ PE+ W +L G D + PEDR W +D YD Sbjct: 24 KQKQELTARTHEPIAIVGMGCRFPGSVRTPEALWRVLHDGQDLVSRFPEDRGWKVDSLYD 83 Query: 1607 PDPDTPGKTYTRXXXXXXXXXXXXPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP 1666 PDPD+ GK+YT FFGISPREA+ ++PQQRL+LET WE ERAG AP Sbjct: 84 PDPDSYGKSYTVQGGFLHDADRFDAGFFGISPREALALDPQQRLLLETSWETFERAGIAP 143 Query: 1667 SDLRGSRTGVFTGVAANEYAHLLSA---------ESIDKIEPHFITGNALNAISGRVAFA 1717 L+GS TGVF GV N+Y L + + + +E + +A +A SGR++++ Sbjct: 144 DSLQGSATGVFVGVMYNDYGTRLWSLQRDAGFVLHAPEDLEGYMGVSSAPSAASGRLSYS 203 Query: 1718 LGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLS 1777 G +GPAV +DTACSS+LVA+H A QAL+ G+C LALAGGV V+ +P V+ SR R LS Sbjct: 204 FGLQGPAVTLDTACSSSLVAIHLAAQALRRGECTLALAGGVTVMATPGGFVSFSRQRALS 263 Query: 1778 PVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVP 1837 P GRCK F A ADG EG G+L+L+RLSDA R+G + AV+ S+VNQDG S GLT P Sbjct: 264 PDGRCKAFSADADGAGWGEGAGMLLLERLSDAKRNGHPILAVLRGSAVNQDGKSQGLTAP 323 Query: 1838 NGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQXXXXXXXXXXXXXXPLLM 1897 NG AQQR+I L A L+ VD +EAHGTGT LGDPIE Q P+ + Sbjct: 324 NGPAQQRVILQALDNARLTPNQVDAVEAHGTGTKLGDPIEAQALLATYGQAHTPEAPVWL 383 Query: 1898 GSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPW 1957 GS+K+N+GHT++A+G AG++K+VL+LQH +LP +LH + PSPHI W + ++++ PW Sbjct: 384 GSLKSNLGHTQAAAGVAGVMKMVLALQHQMLPATLHAQTPSPHIDWSSGTLQLVQSARPW 443 Query: 1958 QTNGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHXXXXXXXXXXXXXXXGTDDSPQVLALS 2017 QTNG+ RRAGVSSFG +GTNAH+++EEAP + + LS Sbjct: 444 QTNGQPRRAGVSSFGVSGTNAHLILEEAPLE-------QAATEQRAAATAPVAALPFLLS 496 Query: 2018 ARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVDSVXXXXXXXXX 2077 ++ EAL A+R L + DV ++ R+HFE RAALV + Sbjct: 497 GKTEEALKAQAQRLHQHLQRHEDAALVDVSYSLATTRAHFEQRAALVASTREELLAALAA 556 Query: 2078 XXXXXTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADM 2137 + +V ++F GQGSQ+ GM R L + F V C A A Sbjct: 557 LANGESAPSLVVAPRSADGKVVFVFPGQGSQWQGMGRALLRSSDAFRAEVEACEAAFAPY 616 Query: 2138 LPRPLLDVLFATDRETADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYA 2197 + L + L + D+L QP LF + + LA W+S + V+GHS G+ A Sbjct: 617 IDGSLREALEGGSSDRVDVL------QPVLFTMMVSLAAHWRSLGVVAAAVVGHSQGEVA 670 Query: 2198 AACVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF-PRVSVGAYN 2256 AA VAG SLDD A+++A R R + G M AV AE + F ++++GA N Sbjct: 671 AAYVAGALSLDDAAQIVALRSRALRRVAGRGAMAAVELGAEQLATYLAPFEEQLAIGAVN 730 Query: 2257 GPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDXXXXXXXXXXXXX 2315 P ++++G L+ ++E+ ++G+ +HA H L++P+ Sbjct: 731 SPRASLVAGQPAALDALLEKLAEDGVYTQKARGNHASHCRLVEPLAQELTDALQGIRPST 790 Query: 2316 PTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLT 2375 +PL TG L G LDA YW ++ R PV F + + A G + +E+ P PVL+ Sbjct: 791 CAIPLYSTVTGTRLEGH-ELDADYWYQNLRAPVLFQSATERLLADGHDLFVELSPHPVLS 849 Query: 2376 GAAVQVWPEHMAAPRAVASLRKGVADRRQIADALASAYVGGHRPDFAAVHRQ-PRRPVEL 2434 + + + + V SLR+G ++ +L + GH+ D+ A R V L Sbjct: 850 LPLYETFDAREHSAQVVTSLRRGDGTHARMLLSLGELHNRGHKLDWHAFFAPWHPRTVPL 909 Query: 2435 PTYPFQRRRFWPKAS-SIAVDGGTAASGILGSGKDLASGDTIYTSRL 2480 PTY FQ RFW + + + + D ++ S + + GD RL Sbjct: 910 PTYAFQYERFWLEGTRNQSRDSASSGSAESSFWRSVEGGDADGLERL 956 Score = 164 bits (415), Expect = 2e-37 Identities = 162/566 (28%), Positives = 240/566 (42%), Gaps = 39/566 (6%) Query: 988 DWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGELYVVHIAA 1047 +W LVG + A+++ A+A HQ D L++++ A VV + + Sbjct: 2816 EWALVGPEDASLISHANATGVSLTHHQ---------DLNALLESIERGGAFPEVVV-VPS 2865 Query: 1048 GDGAAAPMRDLLRVQH----RTLGGLRRLFRAANDAELRSPIWLVTRDGQRVT-DTDTVV 1102 D AP+RD++ H TLG L+ A R + +VTR D D + Sbjct: 2866 YD--VAPLRDVIDAAHSTAAHTLGVLQTWLAEERFATAR--LIVVTRGAIATRPDEDVLG 2921 Query: 1103 PEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLIARI---TSPRD--GEDQIALRG 1157 Q+ LWG R A E P L D+ + L T+P E Q+A+R Sbjct: 2922 LAQASLWGLVRVAQSEHPDASLTLVDVDNREDSLHALFGLFGSRTAPNALAAEPQLAVRA 2981 Query: 1158 DAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLAS-HGAGHVVLTSRR 1216 V PRL R T P P T L+TGG G +G +A ++ + HGA H++L SR+ Sbjct: 2982 GNVSVPRLARLTEAPDAHARPFDPAGTLLITGGTGTLGRLLARHVVTKHGARHLLLASRQ 3041 Query: 1217 EPXXXXXXXXXXXXEQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGT 1276 + + V+ DV+D + RL+ V A PL G++H AG + Sbjct: 3042 GLAAPGASELVSDLAEAGAEATVVACDVSDRSALQRLVAAVPAN-HPLTGVLHLAGVLDD 3100 Query: 1277 TPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAA 1336 + L D V K+ A+HL E L DL FV SS++ V G GQ Y AA Sbjct: 3101 AVIESLTPKHFDTVLRVKLDAAYHLHELT--LEHDLAAFVMFSSLSGVLGSAGQANYAAA 3158 Query: 1337 NAFLDGLAWRLRERGVTAVSVNFGPWAAGMA-----DAESRARLEQRGVRTLSPAEALAG 1391 N FLD LA + +G +++++G W A A R + G+R LS E LA Sbjct: 3159 NTFLDALAHHRKAQGRHGLAIDWGYWEDRSALTAHLTAADLQRFARSGLRPLSAQEGLAL 3218 Query: 1392 MADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELXXXXXXXXXXXXXXXXXXL 1451 + P +VA + L + A L L S L L Sbjct: 3219 FDAALTRPDAVLVAVRLDAMALAKHANA-----LPPLLSGLVPAKVARPMASTGTSVASL 3273 Query: 1452 VEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRD-EAGFFDLGMDSLMAVELRRRIE 1510 ++L V++R + + + VA V + + D E +LG+DSLMA+E+R R+ Sbjct: 3274 QQRLASLVVEERAPALLEIVCSEVATVLGLASPNALDPERPLQELGLDSLMALEIRNRLS 3333 Query: 1511 QGVGKDIPVTLVMDHPRLSDAADYLL 1536 G + TL+ DHP + LL Sbjct: 3334 AATGLRLRATLLFDHPTAAALTQALL 3359 Score = 142 bits (357), Expect = 1e-30 Identities = 111/357 (31%), Positives = 158/357 (44%), Gaps = 18/357 (5%) Query: 3298 LITGGLGAIGLHTAAYLAQLGAGDIVLTSRR-DPDESAQRAIDEITERHKCRIHTYAADV 3356 LITGG G +G H A +LA GA +VL SRR + A++ DE++E R+ A DV Sbjct: 1220 LITGGTGGLGAHVARWLASKGAQHLVLVSRRGELSPGAEQLHDELSEL-GARVTIAACDV 1278 Query: 3357 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXXX 3416 D A + LL + AE + + H GV L A F ++ KA GA Sbjct: 1279 ADRAALHKLLDALDAEGASIRSVVHAGGVAQQTPLIAMTLREFAEVVSGKARGAQFLHER 1338 Query: 3417 XXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGG 3476 GQ YA NA LD L RR G AT + +G W G Sbjct: 1339 FDAQPLDAFVLFSSGSSSWGGGGQGAYAAGNAFLDALAEHRRGLGRAATSVAWGAWAGDG 1398 Query: 3477 MAS--SEAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARP 3534 M + ++ + + +G++P+ P A+ ALA+ + + + TV +W R A SAR Sbjct: 1399 MVTLLDDSGESALRTRGILPMSPELAIAALAQALDHRETKLTVANMDWARFAPAFASARS 1458 Query: 3535 PILDLVLPSAAGEATG----------DSELLKQLMEIPIPQRAGFVTEFLQREVQNFL-- 3582 L L A G G ++ELL L ++ P R + + E L Sbjct: 1459 RPLLHDLAEAKGALEGAEGTSALEGRETELLAHLRKLTEPDRRRLLLSRVLEETAAVLGH 1518 Query: 3583 RLASPPAASSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYL 3639 AS A F ++G DSL+A+ELR L S G K + AT FD+P+ +A +L Sbjct: 1519 ADASRVEAKRGFFEMGLDSLLALELRKCLQSATGLK--LPATIAFDHPSPEHVAAFL 1573 Score = 139 bits (351), Expect = 6e-30 Identities = 112/363 (30%), Positives = 164/363 (45%), Gaps = 17/363 (4%) Query: 3298 LITGGLGAIGLHTAAYLA-QLGAGDIVLTSRRD-PDESAQRAIDEITERHKCRIHTYAAD 3355 LITGG G +G A ++ + GA ++L SR+ A + ++ E A D Sbjct: 3010 LITGGTGTLGRLLARHVVTKHGARHLLLASRQGLAAPGASELVSDLAEAG-AEATVVACD 3068 Query: 3356 VGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHXXX 3415 V D + + L+A + A PL G+ HLAGVLDDA++ + P+ F T L K A H Sbjct: 3069 VSDRSALQRLVAAVPAN-HPLTGVLHLAGVLDDAVIESLTPKHFDTVLRVKLDAAYHLHE 3127 Query: 3416 XXXXXXXXXXXXXXXXXXXXXXPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQG 3475 GQANYA AN LD L R+AQG I++G W Sbjct: 3128 LTLEHDLAAFVMFSSLSGVLGSAGQANYAAANTFLDALAHHRKAQGRHGLAIDWGYWEDR 3187 Query: 3476 GMASSEAATANI---TAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSA 3532 ++ A++ GL PL L + ++ + AK +A Sbjct: 3188 SALTAHLTAADLQRFARSGLRPLSAQEGLALFDAALTRPDAVLVAVRLDAMALAK-HANA 3246 Query: 3533 RPPILDLVLPS-----AAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASP 3587 PP+L ++P+ A T + L ++L + + +RA + E + EV L LASP Sbjct: 3247 LPPLLSGLVPAKVARPMASTGTSVASLQQRLASLVVEERAPALLEIVCSEVATVLGLASP 3306 Query: 3588 PAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPD 3645 A +LG DSLMA+E+RNRL + G + AT +FD+PT L + L+G L Sbjct: 3307 NALDPERPLQELGLDSLMALEIRNRLSAATG--LRLRATLLFDHPTAAALTQALLGWLVP 3364 Query: 3646 AEA 3648 EA Sbjct: 3365 DEA 3367 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.318 0.135 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 29,502,470,821 Number of extensions: 1275482978 Number of successful extensions: 3636932 Number of sequences better than 10.0: 34835 Number of HSP's gapped: 3474755 Number of HSP's successfully gapped: 66486 Length of query: 3652 Length of database: 4,236,830,644 Length adjustment: 158 Effective length of query: 3494 Effective length of database: 2,260,588,132 Effective search space: 7898494933208 Effective search space used: 7898494933208 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 91 (39.7 bits)