BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_0604 (322 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|A0QQ27|A0QQ27_MYCS2 Tax_Id=246196 SubName: Full=Glyoxylate re... 613 e-173 tr|A4T0T7|A4T0T7_MYCGI Tax_Id=350054 SubName: Full=D-isomer spec... 460 e-127 tr|A1T252|A1T252_MYCVP Tax_Id=350058 SubName: Full=D-isomer spec... 449 e-124 tr|B2HNV3|B2HNV3_MYCMM Tax_Id=216594 (serA3)SubName: Full=D-3-ph... 421 e-116 tr|A0PN51|A0PN51_MYCUA Tax_Id=362242 (serA3)SubName: Full=D-3-ph... 421 e-116 tr|B1MJP9|B1MJP9_MYCA9 Tax_Id=561007 SubName: Full=2-hydroxyacid... 396 e-108 tr|A8U2W3|A8U2W3_9PROT Tax_Id=331869 SubName: Full=D-3-phosphogl... 263 2e-68 tr|B7WZH6|B7WZH6_COMTE Tax_Id=399795 SubName: Full=D-isomer spec... 181 9e-44 tr|C6B539|C6B539_RHILS Tax_Id=395491 SubName: Full=D-isomer spec... 179 6e-43 tr|Q1M3M6|Q1M3M6_RHIL3 Tax_Id=216596 SubName: Full=Putative halo... 177 2e-42 tr|Q92YX6|Q92YX6_RHIME Tax_Id=382 SubName: Full=Dehydrogenase;[R... 172 5e-41 tr|Q2JYR7|Q2JYR7_RHIEC Tax_Id=347834 SubName: Full=Putative phos... 172 5e-41 sp|Q9YAW4|GYAR_AERPE Tax_Id=56636 (gyaR)RecName: Full=Glyoxylate... 170 3e-40 tr|D3FEC2|D3FEC2_CONWI Tax_Id=469383 SubName: Full=Glyoxylate re... 169 4e-40 tr|C6WHA2|C6WHA2_ACTMD Tax_Id=446462 SubName: Full=D-isomer spec... 167 1e-39 tr|D2PZS0|D2PZS0_KRIFD Tax_Id=479435 SubName: Full=D-isomer spec... 165 8e-39 tr|A6ULM8|A6ULM8_SINMW Tax_Id=366394 SubName: Full=D-isomer spec... 165 8e-39 tr|D0DD60|D0DD60_9RHOB Tax_Id=501479 SubName: Full=D-3-phosphogl... 165 8e-39 tr|Q9RKF9|Q9RKF9_STRCO Tax_Id=1902 SubName: Full=Putative dehydr... 164 1e-38 tr|D3F6T6|D3F6T6_CONWI Tax_Id=469383 SubName: Full=D-isomer spec... 163 2e-38 tr|D2Z4S7|D2Z4S7_9BACT Tax_Id=469381 SubName: Full=D-isomer spec... 163 2e-38 tr|D1Y1W8|D1Y1W8_9BACT Tax_Id=352165 SubName: Full=Phosphoglycer... 162 5e-38 tr|B8KTN8|B8KTN8_9GAMM Tax_Id=565045 SubName: Full=Glyoxylate re... 162 5e-38 tr|A9EGI0|A9EGI0_9RHOB Tax_Id=391624 SubName: Full=Putative dehy... 162 5e-38 tr|Q7WNI7|Q7WNI7_BORBR Tax_Id=518 SubName: Full=Putative dehydro... 162 7e-38 tr|D1C330|D1C330_SPHTD Tax_Id=479434 SubName: Full=Glyoxylate re... 162 7e-38 tr|C8SFI3|C8SFI3_9RHIZ Tax_Id=536019 SubName: Full=D-isomer spec... 162 7e-38 tr|D3PWA4|D3PWA4_STANL Tax_Id=446470 SubName: Full=Phosphoglycer... 161 1e-37 tr|A8TU17|A8TU17_9PROT Tax_Id=331869 SubName: Full=2-hydroxyacid... 161 1e-37 tr|D3F8A2|D3F8A2_CONWI Tax_Id=469383 SubName: Full=D-isomer spec... 159 4e-37 tr|D3F4X6|D3F4X6_CONWI Tax_Id=469383 SubName: Full=D-isomer spec... 159 4e-37 tr|A1HMI9|A1HMI9_9FIRM Tax_Id=401526 SubName: Full=Phosphoglycer... 159 4e-37 tr|D0WLS2|D0WLS2_9ACTO Tax_Id=649743 SubName: Full=Phosphoglycer... 159 5e-37 tr|D0DAV5|D0DAV5_9RHOB Tax_Id=501479 SubName: Full=D-3-phosphogl... 158 8e-37 tr|D3ICZ0|D3ICZ0_9BACT Tax_Id=575614 SubName: Full=Glycerate deh... 158 1e-36 tr|A4AC31|A4AC31_9GAMM Tax_Id=314285 SubName: Full=Glycerate deh... 158 1e-36 tr|Q8TYK0|Q8TYK0_METKA Tax_Id=2320 SubName: Full=Predicted dehyd... 157 1e-36 tr|Q986P2|Q986P2_RHILO Tax_Id=381 SubName: Full=Phosphoglycerate... 157 2e-36 tr|B8DYJ5|B8DYJ5_DICTD Tax_Id=515635 SubName: Full=D-3-phosphogl... 157 2e-36 tr|D2QPL3|D2QPL3_SPILD Tax_Id=504472 SubName: Full=D-isomer spec... 156 3e-36 tr|A4YX94|A4YX94_BRASO Tax_Id=114615 SubName: Full=Putative D-3-... 156 4e-36 tr|C5EEM4|C5EEM4_9FIRM Tax_Id=457421 SubName: Full=D-isomer spec... 156 4e-36 tr|A8S7W6|A8S7W6_9FIRM Tax_Id=411485 SubName: Full=Putative unch... 156 4e-36 tr|A6W4F1|A6W4F1_KINRD Tax_Id=266940 SubName: Full=D-isomer spec... 155 5e-36 tr|C8SFV5|C8SFV5_9RHIZ Tax_Id=536019 SubName: Full=D-isomer spec... 155 5e-36 >tr|A0QQ27|A0QQ27_MYCS2 Tax_Id=246196 SubName: Full=Glyoxylate reductase; EC=1.1.1.26;[Mycobacterium smegmatis] Length = 322 Score = 613 bits (1580), Expect = e-173 Identities = 305/322 (94%), Positives = 305/322 (94%) Query: 1 MAVNPGTVRVLAHFAPSNTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRP 60 MAVNPGTVRVLAHFAPSNTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRP Sbjct: 1 MAVNPGTVRVLAHFAPSNTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRP 60 Query: 61 ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAAL 120 ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAAL Sbjct: 61 ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAAL 120 Query: 121 RRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLH 180 RRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLH Sbjct: 121 RRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLH 180 Query: 181 TSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPI 240 TSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPI Sbjct: 181 TSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPI 240 Query: 241 VDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSI 300 VDE DVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSI Sbjct: 241 VDEAALIEALRGGRLAAAGLDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSI 300 Query: 301 GVENCRRIRDGEPLAHLVNEAR 322 GVENCRRIRDGEPLAHLVNEAR Sbjct: 301 GVENCRRIRDGEPLAHLVNEAR 322 >tr|A4T0T7|A4T0T7_MYCGI Tax_Id=350054 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding;[Mycobacterium gilvum] Length = 315 Score = 460 bits (1184), Expect = e-127 Identities = 222/313 (70%), Positives = 260/313 (83%), Gaps = 1/313 (0%) Query: 8 VRVLAHFAPSNTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLN 67 +RVLAHF P V +FL+PH DWLD+R+C E+DDETFYREL DA+V+WHVLRPI+GDDL+ Sbjct: 1 MRVLAHFLPGPKVTEFLSPHTDWLDIRYCAEDDDETFYRELPDAEVIWHVLRPISGDDLS 60 Query: 68 RAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLD 127 +AP+LRLVHKLGAGVNT+DV+TAT GI VANMPGANAPSVAEGT+LLMLAALRRLP+LD Sbjct: 61 KAPKLRLVHKLGAGVNTVDVDTATARGIAVANMPGANAPSVAEGTLLLMLAALRRLPELD 120 Query: 128 RATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTG 187 RATR G GWP+DPTLG++VRD+GGCTVGLVGYGN+AK+VERI+LA+GAE V+HTSTRD G Sbjct: 121 RATRTGNGWPSDPTLGESVRDLGGCTVGLVGYGNIAKQVERILLAIGAE-VVHTSTRDDG 179 Query: 188 HPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXX 247 P WR LPDLL+ SDIVSLHLPLT + GLLG +A+A MK AVLVNT+RG IVDE Sbjct: 180 LPGWRTLPDLLSESDIVSLHLPLTGATEGLLGRKALAQMKTDAVLVNTSRGAIVDEAALV 239 Query: 248 XXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRR 307 DVF EP+P+D+PLLGL NVVLTPHVTWYTADTMRRYL ++NC R Sbjct: 240 DALRAGTLAAAGLDVFAVEPVPSDNPLLGLPNVVLTPHVTWYTADTMRRYLEFALDNCER 299 Query: 308 IRDGEPLAHLVNE 320 +RDG LAH+VN+ Sbjct: 300 LRDGRALAHVVND 312 >tr|A1T252|A1T252_MYCVP Tax_Id=350058 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding;[Mycobacterium vanbaalenii] Length = 318 Score = 449 bits (1156), Expect = e-124 Identities = 223/316 (70%), Positives = 258/316 (81%), Gaps = 4/316 (1%) Query: 8 VRVLAHFAPS---NTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRPITGD 64 +RVLAHF P + V++FLAP DWLDVRFC E+DD+TFYREL DA+V+WHVLRP++G+ Sbjct: 1 MRVLAHFVPGGPDSKVIEFLAPCRDWLDVRFCAEDDDDTFYRELADAEVIWHVLRPLSGE 60 Query: 65 DLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLP 124 DL RAPRLRLVHKLGAGVNTIDV+ AT G+ VANMPGANA SVAEGT+LLMLAALRRLP Sbjct: 61 DLARAPRLRLVHKLGAGVNTIDVDAATARGVAVANMPGANAESVAEGTLLLMLAALRRLP 120 Query: 125 QLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTR 184 LDRATR GRGWP+DPTLG+TVRDIGGCTVGLVGYGN+AK+VERI++AMGA+ V+HTSTR Sbjct: 121 VLDRATREGRGWPSDPTLGETVRDIGGCTVGLVGYGNIAKQVERILVAMGAD-VIHTSTR 179 Query: 185 DTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEX 244 D G WR+LPDLL+A DIVSLHLPLTD + GLLG +A+A MK AVLVNT+RGPIVDE Sbjct: 180 DDGSAGWRSLPDLLSACDIVSLHLPLTDATAGLLGRDALARMKSDAVLVNTSRGPIVDEE 239 Query: 245 XXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVEN 304 DVF EP+PAD+PLL L NVVLTPHVTWYTADTMRRYL V+N Sbjct: 240 ALADALRTGKLAAAGLDVFAVEPVPADNPLLRLPNVVLTPHVTWYTADTMRRYLEFAVDN 299 Query: 305 CRRIRDGEPLAHLVNE 320 C R+RDG L ++VN+ Sbjct: 300 CERLRDGRNLVNVVND 315 >tr|B2HNV3|B2HNV3_MYCMM Tax_Id=216594 (serA3)SubName: Full=D-3-phosphoglycerate dehydrogenase SerA3;[Mycobacterium marinum] Length = 320 Score = 421 bits (1083), Expect = e-116 Identities = 210/312 (67%), Positives = 244/312 (78%), Gaps = 1/312 (0%) Query: 8 VRVLAHFAPSNTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLN 67 +RVLAHF P VL+F+A DWLD+R+C E+DD FYREL A+V+WHVLRP++G DL Sbjct: 5 LRVLAHFVPGEKVLEFVAAQRDWLDIRWCAEDDDSGFYRELDHAEVIWHVLRPLSGADLQ 64 Query: 68 RAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLD 127 RAPRLRLV KLGAGVNTIDV TAT+ GI VANMPGANAPSVAEGTVLLMLAALRRLP+LD Sbjct: 65 RAPRLRLVQKLGAGVNTIDVATATKHGIAVANMPGANAPSVAEGTVLLMLAALRRLPELD 124 Query: 128 RATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTG 187 ATR GRGWPTDP LG++VRDIG CTVGL+GYGN+AKRV IV AMGA VLHTSTRD G Sbjct: 125 AATRQGRGWPTDPQLGESVRDIGSCTVGLIGYGNIAKRVATIVSAMGA-TVLHTSTRDDG 183 Query: 188 HPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXX 247 P WR LP+LLA SDIVSLHLPLT + LL +A+A MKP ++L+NT+RG ++DE Sbjct: 184 RPGWRPLPELLATSDIVSLHLPLTPHTDRLLDADALAQMKPNSLLINTSRGAVIDEDALV 243 Query: 248 XXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRR 307 DVF EP+ ++PLL LDNVVLTPHVTWYT DTMRRYL+ V+NCRR Sbjct: 244 DALRSGSLAAAGLDVFAVEPVVPENPLLRLDNVVLTPHVTWYTVDTMRRYLTEAVDNCRR 303 Query: 308 IRDGEPLAHLVN 319 +RDG LA++VN Sbjct: 304 LRDGLSLANVVN 315 >tr|A0PN51|A0PN51_MYCUA Tax_Id=362242 (serA3)SubName: Full=D-3-phosphoglycerate dehydrogenase SerA3;[Mycobacterium ulcerans] Length = 320 Score = 421 bits (1082), Expect = e-116 Identities = 211/312 (67%), Positives = 243/312 (77%), Gaps = 1/312 (0%) Query: 8 VRVLAHFAPSNTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLN 67 +RVLAHF P VL+F+A DWLD+R+C E+DD FYREL A+V+WHVLRP++G DL Sbjct: 5 LRVLAHFVPGEKVLEFVAAQRDWLDIRWCAEDDDSGFYRELDHAEVIWHVLRPLSGADLQ 64 Query: 68 RAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLD 127 RAPRLRLV KLGAGVNTIDV TAT+ GI VANMPGANAPSVAEGTVLLMLAALRRLP+LD Sbjct: 65 RAPRLRLVQKLGAGVNTIDVATATKHGIAVANMPGANAPSVAEGTVLLMLAALRRLPELD 124 Query: 128 RATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTG 187 ATR GRGWPTDP LG++VRDIG CTVGL+GYGN+AKRV IV AMGA VLHTSTRD G Sbjct: 125 AATRQGRGWPTDPQLGESVRDIGSCTVGLIGYGNIAKRVATIVSAMGA-TVLHTSTRDDG 183 Query: 188 HPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXX 247 P WR LP+LLA SDIVSLHLPLT + LL +A+A MKP ++L+NT+RG +VDE Sbjct: 184 RPGWRPLPELLATSDIVSLHLPLTPHTDRLLDADALARMKPNSLLINTSRGAVVDEDALV 243 Query: 248 XXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRR 307 DVF EP+ ++PLL LDNVVLTPHVTWYT DTMRRYL+ V+NCRR Sbjct: 244 DALRSGSLAAAGLDVFAVEPVVPENPLLRLDNVVLTPHVTWYTVDTMRRYLTEAVDNCRR 303 Query: 308 IRDGEPLAHLVN 319 +RDG LA+ VN Sbjct: 304 LRDGLSLANAVN 315 >tr|B1MJP9|B1MJP9_MYCA9 Tax_Id=561007 SubName: Full=2-hydroxyacid dehydrogenase family;[Mycobacterium abscessus] Length = 320 Score = 396 bits (1018), Expect = e-108 Identities = 197/311 (63%), Positives = 234/311 (75%), Gaps = 1/311 (0%) Query: 8 VRVLAHFAPSNTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLN 67 VRVLAHF VL+ LAPH DWLDVRFC E+DD TFY EL ADVLWHVLRP++ DD+ Sbjct: 10 VRVLAHFPSGPRVLEQLAPHADWLDVRFCAEDDDNTFYAELPGADVLWHVLRPLSADDVA 69 Query: 68 RAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLD 127 + RLRL+HK GAGVNTI ++ A + G+ VANMPGANAPSVAEG +LLMLAALR+LP+LD Sbjct: 70 KGERLRLIHKFGAGVNTIALDAAVEHGVAVANMPGANAPSVAEGALLLMLAALRQLPRLD 129 Query: 128 RATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTG 187 R R+G GWPTD +LG++VRDIG CT+GLVGYGN+AK +E+I+LAMGA VLHTSTRD G Sbjct: 130 RDIRSGNGWPTDQSLGESVRDIGSCTIGLVGYGNIAKSLEKILLAMGA-TVLHTSTRDDG 188 Query: 188 HPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXX 247 WR L DLL +SDIVSLHLPLT+ S G+L A+ MKPG+VLVNT+RG +VDE Sbjct: 189 TAGWRGLNDLLTSSDIVSLHLPLTEASTGMLDSAALNRMKPGSVLVNTSRGAVVDEAALV 248 Query: 248 XXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRR 307 DVF EP+ ++PLL L NVVLTPHVTW+TADTM RYL ++NCRR Sbjct: 249 NALQQGPLGAAGLDVFAQEPVSPENPLLALPNVVLTPHVTWFTADTMTRYLHHAIDNCRR 308 Query: 308 IRDGEPLAHLV 318 I +G PLA V Sbjct: 309 IHEGMPLADRV 319 >tr|A8U2W3|A8U2W3_9PROT Tax_Id=331869 SubName: Full=D-3-phosphoglycerate dehydrogenase;[alpha proteobacterium BAL199] Length = 315 Score = 263 bits (672), Expect = 2e-68 Identities = 140/289 (48%), Positives = 184/289 (63%), Gaps = 1/289 (0%) Query: 31 LDVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETA 90 + + C E+DD+ F R L DADVL H LRP+T + APRLRL+ K+G GVNTID+E A Sbjct: 26 VQISTCAEDDDDRFARLLTDADVLLHNLRPVTDAHMAAAPRLRLIQKIGVGVNTIDLEAA 85 Query: 91 TQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIG 150 + GI V NMPG+N+ +V E +LLMLA LRRLP D TR G GW + DT+ ++ Sbjct: 86 EKRGIAVCNMPGSNSRAVMEMMLLLMLACLRRLPVFDARTRRGEGWGWPKEMQDTLGELA 145 Query: 151 GCTVGLVGYGNVAKRVERIVLAMGAEQVLHTST-RDTGHPRWRNLPDLLAASDIVSLHLP 209 G TVGL GYG+V + + +++AMGAE + T + W + LLA SD++SLH+P Sbjct: 146 GRTVGLAGYGSVPEMLAPVLVAMGAEVIYCCRTAKSNAVGTWVDKEQLLARSDVLSLHMP 205 Query: 210 LTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLP 269 LTD +R L +A+AAMKPGA+L+NTARG +VDE DVF EP Sbjct: 206 LTDETRHWLDRDALAAMKPGAILINTARGGLVDEPALIAALGSGQLMGAGLDVFAEEPTA 265 Query: 270 ADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLV 318 +PLL LD VVL PHV ++T +T+ R LSI V+N RR+RDG+ L H V Sbjct: 266 PGNPLLTLDRVVLAPHVAFFTLETLERSLSIAVDNIRRLRDGQDLMHRV 314 >tr|B7WZH6|B7WZH6_COMTE Tax_Id=399795 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding;[Comamonas testosteroni KF-1] Length = 320 Score = 181 bits (460), Expect = 9e-44 Identities = 107/257 (41%), Positives = 145/257 (56%), Gaps = 5/257 (1%) Query: 59 RPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLA 118 +P++ L AP LR+V K GAGV+++D+E A G+ VA ANAP+VAE + LMLA Sbjct: 62 KPVSAAVLRAAPALRIVAKNGAGVDSVDMEAARTQGVAVAVAQAANAPAVAEHALALMLA 121 Query: 119 ALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAE-Q 177 +R+LPQLD+ RAG GW G RD G TVG+VGYG + + ++ A+GA+ Sbjct: 122 LVRQLPQLDQQVRAG-GWAGSNWQG---RDFRGSTVGIVGYGAIGRATAQLAAALGAKVL 177 Query: 178 VLHTSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTAR 237 VL + + +L LL DI+SLH PLT+ +RGL+G +A ++PG++L+NTAR Sbjct: 178 VLRPAGQADDFDCEPDLRRLLPRVDILSLHCPLTEQTRGLIGANELALLRPGSLLINTAR 237 Query: 238 GPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRY 297 GP+VDE D FD EPLP HPL L V+LTPHV T R Sbjct: 238 GPVVDEAALLAALESGHLGGAGLDTFDIEPLPQGHPLARLPQVLLTPHVAGVTRQAALRV 297 Query: 298 LSIGVENCRRIRDGEPL 314 ++ N G PL Sbjct: 298 ATLTAANIVNHLAGRPL 314 >tr|C6B539|C6B539_RHILS Tax_Id=395491 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding;[Rhizobium leguminosarum bv. trifolii] Length = 324 Score = 179 bits (453), Expect = 6e-43 Identities = 111/292 (38%), Positives = 154/292 (52%), Gaps = 7/292 (2%) Query: 32 DVRFCGEEDDETFYRELGDADVLWHVLR-PITGDDLNRAPRLRLVHKLGAGVNTIDVETA 90 D+R D ET RE A +L V+R PI AP LR + GAG++ + ++ A Sbjct: 23 DLRVASAPDPETLLREGRGAGIL--VIRAPIPPAYFEDAPALRAAIRHGAGLDMVPMDAA 80 Query: 91 TQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIG 150 T+ G+LVAN+PGANA +VAE L+ LA LRR +DR R GW D D+ Sbjct: 81 TRAGVLVANVPGANASTVAEHVFLVTLALLRRFRLMDRELRQ-NGWVAGRARSDAAVDLA 139 Query: 151 GCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTGHP---RWRNLPDLLAASDIVSLH 207 G T+G+VG GNV K + +I +V+ TS P R+ + +L+A +DIV L Sbjct: 140 GRTIGIVGMGNVGKAIFKIAKFGFGLEVVATSRSPESVPDGVRFLTIDELVATADIVVLC 199 Query: 208 LPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEP 267 PLT + GLL I MKP A+LVN +RGP++D+ DVF T+P Sbjct: 200 CPLTPETTGLLNAGRIGRMKPAAILVNVSRGPVIDDAALVEALRDGRVGGAALDVFATQP 259 Query: 268 LPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 LP DHP G DNV++TPH+ T ++M R + R+ G+ +L N Sbjct: 260 LPLDHPYFGFDNVIVTPHLAGLTEESMMRMGTGAASEALRVIKGDLPVNLCN 311 >tr|Q1M3M6|Q1M3M6_RHIL3 Tax_Id=216596 SubName: Full=Putative haloacid dehydrogenase;[Rhizobium leguminosarum bv. viciae] Length = 324 Score = 177 bits (449), Expect = 2e-42 Identities = 109/291 (37%), Positives = 153/291 (52%), Gaps = 5/291 (1%) Query: 32 DVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETAT 91 D+R D ET RE A ++ V PI AP LR + GAG++ + ++ AT Sbjct: 23 DLRVASAPDPETLLREGRGAGIVV-VRAPIPPAFFEDAPALRAAIRHGAGLDMVPLDAAT 81 Query: 92 QLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGG 151 + G+LVAN+PGANA +VAE L+ LA LRR +DR R GW DT D+ G Sbjct: 82 RAGVLVANVPGANASTVAEHVFLVTLALLRRFRAMDRDLRQS-GWAAGRAQSDTAVDLAG 140 Query: 152 CTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTGHP---RWRNLPDLLAASDIVSLHL 208 T+G++G GNV K + +I +V+ TS P R+ + +L+A +DIV L Sbjct: 141 RTMGIIGMGNVGKAILKIAKFGFGLEVVATSRSPESVPDGVRFLKIDELVATADIVLLCC 200 Query: 209 PLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPL 268 PLT + GLL I MKP A+LVN +RGP++D+ DVF T+PL Sbjct: 201 PLTPETTGLLNAGRIGRMKPTAILVNVSRGPVIDDAALIEALRDGRIGGAALDVFATQPL 260 Query: 269 PADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 P DHP G DNV++TPH+ T ++M R + R+ G+ +L N Sbjct: 261 PLDHPYFGFDNVIVTPHLAGLTEESMMRMGTGAASEALRVIKGDLPVNLRN 311 >tr|Q92YX6|Q92YX6_RHIME Tax_Id=382 SubName: Full=Dehydrogenase;[Rhizobium meliloti] Length = 324 Score = 172 bits (436), Expect = 5e-41 Identities = 105/283 (37%), Positives = 148/283 (52%), Gaps = 5/283 (1%) Query: 32 DVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETAT 91 D+R D ET RE A+++ V PI P LR V + GAG++ I + AT Sbjct: 23 DLRVASAPDPETLLREGEGAEIVI-VRAPIPPAFFGNVPALRAVVRHGAGLDMIPYDAAT 81 Query: 92 QLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGG 151 G+L+AN+P NAP+VAE ++ LA LR+ +DR R GW T D D+ G Sbjct: 82 AAGVLIANVPAVNAPTVAEHVFMVTLALLRQFRPMDRDLR-NMGWSTGRAHSDRALDLAG 140 Query: 152 CTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTGHP---RWRNLPDLLAASDIVSLHL 208 +G++G GNV K V RI +++ S P R+ ++ DLL+ +DIV L Sbjct: 141 RIMGVIGMGNVGKAVFRIAKYGFQLEIVANSRSPESLPDGVRFLSVDDLLSTADIVVLCC 200 Query: 209 PLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPL 268 PLT + GLL E IA MKPGA+LVN +RGP+VD+ DVF T+PL Sbjct: 201 PLTPKTTGLLSRERIARMKPGAILVNVSRGPVVDDAALIEALERGRIGGAALDVFSTQPL 260 Query: 269 PADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDG 311 P +HP DNV++TPH+ + ++M R R+ +G Sbjct: 261 PPEHPYFRQDNVIVTPHLAGISEESMMRMGKGAAAEAIRVMEG 303 >tr|Q2JYR7|Q2JYR7_RHIEC Tax_Id=347834 SubName: Full=Putative phosphoglycerate dehydrogenase protein; EC=1.1.1.95;[Rhizobium etli] Length = 324 Score = 172 bits (436), Expect = 5e-41 Identities = 109/291 (37%), Positives = 152/291 (52%), Gaps = 5/291 (1%) Query: 32 DVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETAT 91 D+R D ET RE A ++ V PI AP LR + GAG++ + +E AT Sbjct: 23 DLRIASAPDPETLLREGRGAGIVI-VRAPIPPVFFEDAPALRAAIRHGAGLDMVPMEAAT 81 Query: 92 QLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGG 151 + G+LVAN+PG NA +VAE L+ LA LRR Q+D R GW D D+GG Sbjct: 82 RAGVLVANVPGVNASTVAEHVFLVTLALLRRFRQMDGDLRQ-NGWAAGRAQADAAVDLGG 140 Query: 152 CTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTGHP---RWRNLPDLLAASDIVSLHL 208 T+G+VG GNV K + +I +V+ TS P R+ + +L+A +DI+ L Sbjct: 141 RTMGIVGMGNVGKAIFKIAKFGFGLEVVATSRSPGSVPEGARFLTIDELVALADILVLCC 200 Query: 209 PLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPL 268 PLT + GLL IA M+P A+LVN +RGP+VD+ DVF T+PL Sbjct: 201 PLTPGTTGLLHAGRIARMRPDAILVNVSRGPVVDDAALIEALRGGRIGGAALDVFATQPL 260 Query: 269 PADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 P DHP G NV++TPH+ T ++M R + R+ G+ +L N Sbjct: 261 PLDHPYFGFANVIVTPHLAGLTEESMMRMGTGAASEALRVIKGDLPVNLRN 311 >sp|Q9YAW4|GYAR_AERPE Tax_Id=56636 (gyaR)RecName: Full=Glyoxylate reductase; EC=1.1.1.26;[Aeropyrum pernix] Length = 335 Score = 170 bits (430), Expect = 3e-40 Identities = 112/290 (38%), Positives = 150/290 (51%), Gaps = 15/290 (5%) Query: 42 ETFYRELGDADVLWHVLRP-ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANM 100 ET + +AD L+ +L I D L++APRLR+V ++ G + IDVE AT+LGI V N Sbjct: 38 ETLLSKAREADALYTLLTDRIDCDLLSQAPRLRIVAQMAVGFDNIDVECATRLGIYVTNT 97 Query: 101 PGANAPSVAEGTVLLMLAALRRLPQLDRATRAGR------GWPTDPTLGDTVRDIGGCTV 154 PG + AE T L+LAA RR+ + D R G GW LG +R G T+ Sbjct: 98 PGVLTEATAEFTWALILAAARRVVEADHFVRWGEWWRLRTGWHPMMMLGVELR---GKTL 154 Query: 155 GLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTGHPR-----WRNLPDLLAASDIVSLHLP 209 G++G G + RV I A G + H+ +R + +R+L DLL SDI+S+HLP Sbjct: 155 GILGMGRIGSRVAEIGKAFGMRIIYHSRSRKREIEKELGAEYRSLEDLLRESDILSIHLP 214 Query: 210 LTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLP 269 LTD +R L+G + MK A+LVNT RG IVD DVF+ EPL Sbjct: 215 LTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALREGWIAAAALDVFEEEPLN 274 Query: 270 ADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 +HPL NVVL PH T +T R + EN G+ +LVN Sbjct: 275 PNHPLTAFKNVVLAPHAASATRETRLRMAMMAAENLVAFAQGKVPPNLVN 324 >tr|D3FEC2|D3FEC2_CONWI Tax_Id=469383 SubName: Full=Glyoxylate reductase; EC=1.1.1.26;[Conexibacter woesei] Length = 309 Score = 169 bits (428), Expect = 4e-40 Identities = 108/262 (41%), Positives = 137/262 (52%), Gaps = 11/262 (4%) Query: 60 PITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAA 119 PI G L+ PRLR+V G GV+ ID+ A + G+ V N P + A+ L+LAA Sbjct: 56 PIDGPLLDACPRLRVVANYGVGVDNIDLAAAAERGVPVGNTPDVLTDASADLAFALLLAA 115 Query: 120 LRRLPQLDRATRAGRG--WPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQ 177 RRLPQ R+GR W D LG D+ G T+G+VG G + + V R A G + Sbjct: 116 ARRLPQTAEDVRSGRWGTWEPDGFLG---HDVTGTTLGIVGAGRIGEAVAR--RARGFDM 170 Query: 178 VLHTSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTAR 237 + T+T G P LP+LL SD VSLHLPLT +R L+ A+ MK A+LVNTAR Sbjct: 171 TVLTATSRAGTP----LPELLERSDFVSLHLPLTPATRHLIDAAALRRMKRTAILVNTAR 226 Query: 238 GPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRY 297 GPIVD DV D EPLP HPLL NV++ PH+ T T R Sbjct: 227 GPIVDTDALTRALHDGTIAGAALDVTDPEPLPPSHPLLAAPNVLVVPHIGSATPRTRARM 286 Query: 298 LSIGVENCRRIRDGEPLAHLVN 319 + V+N GEPL H V+ Sbjct: 287 ADLAVDNVLAGLAGEPLPHPVS 308 >tr|C6WHA2|C6WHA2_ACTMD Tax_Id=446462 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding;[Actinosynnema mirum] Length = 306 Score = 167 bits (424), Expect = 1e-39 Identities = 109/260 (41%), Positives = 140/260 (53%), Gaps = 18/260 (6%) Query: 61 ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAAL 120 + G+ + RAPRLR+V + G GV+T+DVE A +LGI V PGANA SVAE V LMLA Sbjct: 49 VDGEMMRRAPRLRVVARHGVGVDTVDVEAAEELGIAVTTTPGANAQSVAEHAVALMLAVR 108 Query: 121 RRLPQLDRATRAGRGWPTDPTLGDTV------RDIGGCTVGLVGYGNVAKRVERIVL-AM 173 R + A R G G G+ V R++ G VGLVG+G +A+RV I Sbjct: 109 R---GIGVAVRGGGGGGGGEGGGEGVRGAIRGRELSGAVVGLVGFGRIAQRVGAICAGGF 165 Query: 174 GAEQVLHTSTRDTGHPRWR-----NLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKP 228 G + H G R L +LL+ SD VS+H+PLT+ +RGL+G E + M Sbjct: 166 GMRVLAHDPMLGDGGVRAAGAEPVGLDELLSLSDNVSVHVPLTERTRGLIGAERLRLMPE 225 Query: 229 GAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTW 288 GAV+VNTARG +VDE DV EPLP DHPL NVV+TPHV Sbjct: 226 GAVVVNTARGGVVDEDALVVALREGRLGGAGLDVTSVEPLPGDHPLWDEPNVVITPHVGA 285 Query: 289 YTADTMRRYLSIGVENCRRI 308 T + MRR + +E R+ Sbjct: 286 QTVEAMRR---VALEAAERV 302 >tr|D2PZS0|D2PZS0_KRIFD Tax_Id=479435 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein;[Kribbella flavida] Length = 338 Score = 165 bits (417), Expect = 8e-39 Identities = 103/249 (41%), Positives = 135/249 (54%), Gaps = 6/249 (2%) Query: 60 PITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAA 119 P T L AP LR + G ++V AT+ GI VA+ PG NA + AE V LM+ A Sbjct: 77 PFTERVLQAAPDLRFLVCCRGGPVNVNVPAATERGITVASTPGRNAVAAAEHAVALMMGA 136 Query: 120 LRRLPQLDRATRAGRGWPTDPTLGDTV-RDIGGCTVGLVGYGNVAKRVERIVLAMGAEQV 178 LR+LPQL R G W +D D ++ G TVGL+GYG + +RV R++LA GA+ + Sbjct: 137 LRKLPQLQRTLEQG-AWRSDLYAYDECGSELDGATVGLIGYGAIGQRVSRVMLAFGAKVL 195 Query: 179 LHTSTRDTGHP----RWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVN 234 + D P L +LL SD+VSLH LT+ +RG++G + +A M+ GAVLVN Sbjct: 196 VVDPAYDAASPPEGTEVVGLDELLGRSDVVSLHARLTEQTRGMIGADQLARMRRGAVLVN 255 Query: 235 TARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTM 294 TARG ++D DVF EPLPA LL NVV+TPH+ T T Sbjct: 256 TARGGLLDYEATVDALESGQLGAAAFDVFPAEPLPAGSRLLTAPNVVMTPHLAGATRQTA 315 Query: 295 RRYLSIGVE 303 RR SI E Sbjct: 316 RRAGSIAAE 324 >tr|A6ULM8|A6ULM8_SINMW Tax_Id=366394 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding;[Sinorhizobium medicae] Length = 324 Score = 165 bits (417), Expect = 8e-39 Identities = 102/283 (36%), Positives = 150/283 (53%), Gaps = 5/283 (1%) Query: 32 DVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETAT 91 D+R D ET RE A+++ V I A LR V + GAG++ I +TAT Sbjct: 23 DLRIASAPDPETLLREGAGAEIVI-VRARIPPAFFQLASMLRAVIRHGAGIDMIPYDTAT 81 Query: 92 QLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGG 151 G+L+AN+PGANA +VAE +++ LA LR+ +DR R GW D D+ G Sbjct: 82 AAGVLIANVPGANALTVAEHVLMVSLALLRQFRPMDRDLR-NIGWSAGRAHSDRALDLAG 140 Query: 152 CTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTGHP---RWRNLPDLLAASDIVSLHL 208 T+G+VG G+V K V R +++ S P R+ ++ DL++ +DIV L Sbjct: 141 RTMGIVGMGSVGKAVFRKAKYGFGLEIVANSRAPASLPHGVRFLSVDDLVSTADIVVLCC 200 Query: 209 PLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPL 268 PLT + GL+ + IA MKPG +LVN +RGP+VD+ DVF T+PL Sbjct: 201 PLTPETTGLVSRDRIARMKPGTILVNVSRGPVVDDAALIQALEGGRIGGAALDVFSTQPL 260 Query: 269 PADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDG 311 P +HP L+NV++TPH+ T ++M R + R+ +G Sbjct: 261 PLEHPYFRLNNVIVTPHLAGITEESMMRMGTEAAAEAIRVLEG 303 >tr|D0DD60|D0DD60_9RHOB Tax_Id=501479 SubName: Full=D-3-phosphoglycerate dehydrogenase; EC=1.1.1.95;[Citreicella sp. SE45] Length = 310 Score = 165 bits (417), Expect = 8e-39 Identities = 101/249 (40%), Positives = 140/249 (56%), Gaps = 11/249 (4%) Query: 66 LNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQ 125 L AP LR++ +LG G++ ID+ G++V GAN SVAE + + L+ LR + Sbjct: 59 LEAAPGLRVIGRLGVGLDNIDLGACAARGVVVHPATGANTLSVAEYVISVTLSLLRGVHG 118 Query: 126 LDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRD 185 + A AG WP + +G ++ G +GLVGYG +A+ V AMG + Sbjct: 119 ANAAMIAG-SWPRNALIG---AEVSGRVMGLVGYGGIARAVAERARAMGMQIAAFDPYLP 174 Query: 186 TGHPRWRN-----LPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPI 240 P W++ L LLA++D++SLH+PLT +RGL+GPEAIA+MKPGAV++NTARG I Sbjct: 175 DTDPAWQDVRRCDLGTLLASADVISLHVPLTPETRGLVGPEAIASMKPGAVVINTARGGI 234 Query: 241 VDEXXXXXXXXXXXXXXXXXDVFDTEPLPAD--HPLLGLDNVVLTPHVTWYTADTMRRYL 298 VDE DVF+TEPL A+ GL+N+VLTPHV T + R Sbjct: 235 VDEAALAEGLHSGRLGGAALDVFETEPLTAEAAEKFTGLENLVLTPHVAGVTQEANVRVS 294 Query: 299 SIGVENCRR 307 +I VEN R Sbjct: 295 AITVENVLR 303 >tr|Q9RKF9|Q9RKF9_STRCO Tax_Id=1902 SubName: Full=Putative dehydrogenase;[Streptomyces coelicolor] Length = 344 Score = 164 bits (415), Expect = 1e-38 Identities = 97/285 (34%), Positives = 146/285 (51%), Gaps = 8/285 (2%) Query: 40 DDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVAN 99 D +T AD + IT ++R PRL+++ + G GV+++DVE AT+ GILV N Sbjct: 48 DADTMVVNCAGADAIVVQYAAITEQVMDRLPRLKVIGRYGVGVDSVDVEAATRRGILVCN 107 Query: 100 MPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGY 159 +P +V++ + L L+ R +P+LDR RAG D + +G G+VG Sbjct: 108 VPDYGTEAVSDHAIGLALSVARGIPRLDRGVRAG---SFDLPAVRPLYQVGQRVFGVVGM 164 Query: 160 GNVAKRVERIVLAMGAEQVLHTSTRDTGHPRWR-----NLPDLLAASDIVSLHLPLTDTS 214 G + R +G + + + S D +R L +LL + +VS+H PLT+ + Sbjct: 165 GLIGAATARKAAGLGYDVIAYDSAADPDAQTFRGFRSVGLHELLERAQVVSVHTPLTEQT 224 Query: 215 RGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPL 274 RGLLG +A A M+P A++VNT+RG ++D DV + EPLP DHPL Sbjct: 225 RGLLGADAFARMRPDAIVVNTSRGGVIDTGALVDALKRGAVAGAGIDVHEIEPLPRDHPL 284 Query: 275 LGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 DNVVLTPH+ WY+ ++ VEN G ++VN Sbjct: 285 TSFDNVVLTPHLAWYSEESYAELKRRTVENVVDACAGRTPRNVVN 329 >tr|D3F6T6|D3F6T6_CONWI Tax_Id=469383 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein;[Conexibacter woesei] Length = 324 Score = 163 bits (413), Expect = 2e-38 Identities = 94/253 (37%), Positives = 141/253 (55%), Gaps = 8/253 (3%) Query: 66 LNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQ 125 ++R P+LR++ + G+G + +DVE A GI V +P VA+ T+ L+LA RR+P Sbjct: 64 MDRLPQLRVIARCGSGYDKVDVEGAYARGIEVVYVPDYGVDDVADHTLALLLACARRVPS 123 Query: 126 LDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRD 185 DRA RAG WP LG T+R + G T+GL+G+G +A+ G + ++H D Sbjct: 124 SDRAMRAGL-WPPYADLG-TMRRLRGATLGLLGFGRIARAAAERARGFGMQLLVHDPAVD 181 Query: 186 T------GHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGP 239 G R +L DLL +D +S+HLPLT ++ L+G +AAMK GA+LVNT+RG Sbjct: 182 ADTLAAAGAARAHDLGDLLRRADALSIHLPLTPSTHRLVGAPELAAMKRGALLVNTSRGE 241 Query: 240 IVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLS 299 IVDE DVF+ EPLP D PL+GL++ V+TPH ++ + Sbjct: 242 IVDEDALAAALAGGHLAGAGLDVFEVEPLPQDSPLIGLESAVVTPHSAAFSEQALAELRG 301 Query: 300 IGVENCRRIRDGE 312 +++ R+ G+ Sbjct: 302 RALDDVLRVLAGD 314 >tr|D2Z4S7|D2Z4S7_9BACT Tax_Id=469381 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding;[Dethiosulfovibrio peptidovorans DSM 11002] Length = 318 Score = 163 bits (413), Expect = 2e-38 Identities = 95/282 (33%), Positives = 148/282 (52%), Gaps = 11/282 (3%) Query: 46 RELGDAD-VLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGAN 104 +E+ D D V+ + + + + AP +++V G N +DVE AT G+ + N PG Sbjct: 40 KEISDVDGVITMLTEKVDSEFFDNAPNVKVVSNYAVGYNNVDVEEATSRGVKITNTPGVL 99 Query: 105 APSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPT--LGDTVRDIGGCTVGLVGYGNV 162 + A+ L++AA RR + +R R+G+ PT LG R+I G T+GL+G+G + Sbjct: 100 TEATADIAFGLLVAASRRFTEAERYLRSGKWTCWHPTMLLG---REIFGKTLGLIGFGRI 156 Query: 163 AKRVERIVLAMGAEQVLHT-----STRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGL 217 K V R G + + HT +T PRW + ++L SD +SLH PL D +RGL Sbjct: 157 GKAVARRASGFGMKVIYHTPSGGPATDQGDGPRWVSFEEILEKSDYLSLHCPLNDRTRGL 216 Query: 218 LGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGL 277 +G + + MKP AVLVNT+RGP+VD+ DV+D EP+ + PLL L Sbjct: 217 IGKKELERMKPDAVLVNTSRGPVVDQTSLYESLRDGVIGAAGLDVYDEEPISLEDPLLSL 276 Query: 278 DNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 +NVV+ PH+ T + ++ N + +G+ + VN Sbjct: 277 ENVVMLPHIGSATREARDAMATMAASNMLDVLEGKEPRNPVN 318 >tr|D1Y1W8|D1Y1W8_9BACT Tax_Id=352165 SubName: Full=Phosphoglycerate dehydrogenase; EC=1.1.1.95;[Pyramidobacter piscolens W5455] Length = 343 Score = 162 bits (410), Expect = 5e-38 Identities = 98/245 (40%), Positives = 133/245 (54%), Gaps = 8/245 (3%) Query: 73 RLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRA 132 RL+H+ G G + +D+E A + GI+V+ G N+ VAE TV+LMLA+LR LP+L +A Sbjct: 66 RLIHRWGVGFDAVDIEAAGKKGIIVSICAGVNSQPVAELTVMLMLASLRHLPELMSRAKA 125 Query: 133 GRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTGHPR-- 190 GR D + I G VGLVG G++ +RV V MGAE + R Sbjct: 126 GRKDKEDIIARSWL--ISGKRVGLVGLGSIGRRVAAAVGGMGAEVTYYDPFRAAPETEKE 183 Query: 191 ----WRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXX 246 + L +LL +SDIVSLH+PL D++R L+ A+A MKP A+LVNTARG IVD Sbjct: 184 LGVEFLPLDELLKSSDIVSLHMPLLDSTRHLIDAAALAKMKPSALLVNTARGGIVDTEAL 243 Query: 247 XXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCR 306 D + EPLPADHP LDN+++TPH T D R + ++N Sbjct: 244 LKALAGKCLFGAALDTIENEPLPADHPAFSLDNLIITPHAGGNTEDNNRNMAAYIMDNID 303 Query: 307 RIRDG 311 + G Sbjct: 304 AMESG 308 >tr|B8KTN8|B8KTN8_9GAMM Tax_Id=565045 SubName: Full=Glyoxylate reductase; EC=1.1.1.26;[gamma proteobacterium NOR51-B] Length = 318 Score = 162 bits (410), Expect = 5e-38 Identities = 114/316 (36%), Positives = 160/316 (50%), Gaps = 12/316 (3%) Query: 9 RVLAHFAPSNTVLDFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLR-PITGDDLN 67 +V+A AP +V L+ D+ ++ C L AD + L P+T + Sbjct: 4 KVIATMAPPESVSSQLS---DFCELLTCDPATGVIPDEWLQSADGMLCTLNTPVTAGLFS 60 Query: 68 RAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLD 127 RAP+L++V + GV+ ID++ AT + V N PG S A+ + LMLA RRLP+ D Sbjct: 61 RAPQLKVVSSVSVGVDHIDLDAATAAAVPVGNTPGVLVDSTADLALGLMLAVTRRLPEAD 120 Query: 128 RATRAG---RGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTST- 183 + R G W T LG D+ TVGL+G G + + V + LA GA + T T Sbjct: 121 QFVRKGEWTNAWSTGFFLG---TDLSRSTVGLIGLGPIGQAVAKRALAFGARVIGWTRTP 177 Query: 184 RDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDE 243 R+ ++ ++L+ +DI SLH L +R L+G +A MKPGA+L+NTARG ++DE Sbjct: 178 REIPGVELMSMDEVLSGADITSLHTALVPETRNLIGARELALMKPGAILINTARGGLIDE 237 Query: 244 XXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVE 303 DVF EPLPA+ PLL N VL PH+ TA T + L V Sbjct: 238 -PALVDVLQAGRLKAGLDVFAEEPLPANSPLLTTPNTVLVPHLGSATAATRQAMLDRAVI 296 Query: 304 NCRRIRDGEPLAHLVN 319 N R GEPL + VN Sbjct: 297 NLRAGLAGEPLPYCVN 312 >tr|A9EGI0|A9EGI0_9RHOB Tax_Id=391624 SubName: Full=Putative dehydrogenase;[Oceanibulbus indolifex HEL-45] Length = 320 Score = 162 bits (410), Expect = 5e-38 Identities = 97/292 (33%), Positives = 153/292 (52%), Gaps = 4/292 (1%) Query: 22 DFLAPHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAG 81 D + + + LD+RF +E F + + A + R + L A +RLVH+ G G Sbjct: 21 DKVRGYAEGLDLRFADSFSEEDFAKTVKGAAYIVPRGRGLPASVLRGADSVRLVHQWGTG 80 Query: 82 VNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPT 141 + I V+ A ++G+ VA PG NAP++A+ T+ +M+AALRR+P TRAG+ W P Sbjct: 81 YDKIPVDVAKEMGVTVARSPGVNAPTIADLTIGMMIAALRRIPLHYNNTRAGK-WIV-PE 138 Query: 142 LGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLH--TSTRDTGHPRWRNLPDLLA 199 + RD+ VGL+G+G + + V + + E + + + + R+ ++L Sbjct: 139 IVPGARDLSSQKVGLIGFGAIGQLVAKRLTGFDCEVLYYRRSGEAEGTSARYAERDEILE 198 Query: 200 ASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXX 259 DIVSLH+PLT+ S +G +A MK A+LVNT RG ++DE Sbjct: 199 TCDIVSLHMPLTEASHHTIGAAELARMKADALLVNTGRGGLIDEAALIDTLTNKRIAGAA 258 Query: 260 XDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDG 311 DVF EP+ D+PLL LDNV+ PH+ ++ D ++R + N R +G Sbjct: 259 LDVFTEEPVQPDNPLLRLDNVLPLPHIGGHSEDNLKRMVGHWASNIRAFHEG 310 >tr|Q7WNI7|Q7WNI7_BORBR Tax_Id=518 SubName: Full=Putative dehydrogenase;[Bordetella bronchiseptica] Length = 333 Score = 162 bits (409), Expect = 7e-38 Identities = 110/290 (37%), Positives = 150/290 (51%), Gaps = 9/290 (3%) Query: 32 DVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETAT 91 +VRF DD +AD L +T L A R+R VHK G GV+ IDV+ A Sbjct: 32 EVRFAANYDDRHQLALCREADFLVPGWARLTAGMLEAATRVRAVHKWGIGVDRIDVDAAR 91 Query: 92 QLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGG 151 +LGI +A G+NA VAE V L+L RRL ++R RAG+ WP + ++ I Sbjct: 92 RLGIPLAITAGSNAGPVAELAVALILGVYRRLCYVNREMRAGQ-WP-KAEMRESCFQIHR 149 Query: 152 CTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTG-------HPRWRNLPDLLAASDIV 204 T+GLVG+GN+ +++ R + + +L+ + R LP+LLAASDIV Sbjct: 150 KTIGLVGFGNIGRKLARRLSGFEPDAILYCDQQAAPAEVERALGARRVELPELLAASDIV 209 Query: 205 SLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFD 264 SLHLP T ++R L+ A+ MK GAVL+NTARG +VDE D FD Sbjct: 210 SLHLPCTASTRRLIDAAALQHMKKGAVLINTARGELVDEAALAEALQRGHLLGAGLDAFD 269 Query: 265 TEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPL 314 EP +PLL LD VV+TPH D + + + N R G+PL Sbjct: 270 PEPPDPANPLLALDQVVVTPHAGGGVFDNVAPVAAHVLGNLERFVAGQPL 319 >tr|D1C330|D1C330_SPHTD Tax_Id=479434 SubName: Full=Glyoxylate reductase; EC=1.1.1.26;[Sphaerobacter thermophilus] Length = 324 Score = 162 bits (409), Expect = 7e-38 Identities = 95/264 (35%), Positives = 130/264 (49%), Gaps = 6/264 (2%) Query: 61 ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAAL 120 + GD L+R P +R+V + G + IDV T+ G+ V P + A+ L+LA Sbjct: 55 VDGDLLDRLPSVRVVSNMAVGFDNIDVAACTERGVAVCTTPDVLTETTADLAFGLLLAVA 114 Query: 121 RRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLH 180 RR+P+ A RAG W T +G D+ G T+G+VG G + + V R + H Sbjct: 115 RRIPEGHNAVRAG-AWRTWEPMGYLGPDVHGATLGIVGLGRIGQAVARRARGFNMRVLYH 173 Query: 181 TSTR-----DTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNT 235 R + WR L LLA SD VSLH+PL + +RG++G E + MKP AVL+NT Sbjct: 174 APRRRPEVEEELGAEWRELDALLAESDFVSLHVPLNEQTRGMIGREQLRRMKPSAVLINT 233 Query: 236 ARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMR 295 ARGP+V DV D EPLPADHPLL VV+TPH+ + T Sbjct: 234 ARGPVVQTDALLEAMEQGWIWGAGLDVTDPEPLPADHPLLRYPRVVVTPHIASASFTTRA 293 Query: 296 RYLSIGVENCRRIRDGEPLAHLVN 319 R + N + GE +N Sbjct: 294 RMAELAARNLLAVLRGESPPRCLN 317 >tr|C8SFI3|C8SFI3_9RHIZ Tax_Id=536019 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding;[Mesorhizobium opportunistum WSM2075] Length = 346 Score = 162 bits (409), Expect = 7e-38 Identities = 104/273 (38%), Positives = 143/273 (52%), Gaps = 8/273 (2%) Query: 48 LGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPS 107 +GDA++L L P++ D + R P L+LV G ID+ A GI V N+PG NA + Sbjct: 70 IGDAEILVTQLAPLSEDMMRRLPALKLVAVSRGGPINIDMAAARDHGITVVNVPGRNATA 129 Query: 108 VAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGD-TVRDIGGCTVGLVGYGNVAKRV 166 VAE T+ +LA R + A R G W D D T R++G TVG+VGYGN+ +V Sbjct: 130 VAEFTIGAILAETRLIRVGHEALRKGE-WRGDLYRADRTGRELGEMTVGVVGYGNIGTKV 188 Query: 167 ERIVLAMG-----AEQVLHTSTRD-TGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGP 220 R++ A G ++ + S D L DLL+ SD+V+LH +T+ +RGL+G Sbjct: 189 VRLLRAFGCHVLVSDPYVQLSAEDHNAGVELVGLDDLLSRSDVVTLHSRVTEETRGLIGK 248 Query: 221 EAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNV 280 + IA MKPG + VNTARGP+VD + F EP+P+D PLL L NV Sbjct: 249 DTIARMKPGVIFVNTARGPLVDYDALNEALVSGQIASAMLETFAVEPVPSDWPLLQLPNV 308 Query: 281 VLTPHVTWYTADTMRRYLSIGVENCRRIRDGEP 313 LTPH+ + T+ E RR G P Sbjct: 309 TLTPHIAGASVRTVTYAAEQAAEEVRRYIAGLP 341 >tr|D3PWA4|D3PWA4_STANL Tax_Id=446470 SubName: Full=Phosphoglycerate dehydrogenase; EC=1.1.1.95;[Stackebrandtia nassauensis] Length = 324 Score = 161 bits (407), Expect = 1e-37 Identities = 104/261 (39%), Positives = 139/261 (53%), Gaps = 14/261 (5%) Query: 69 APRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDR 128 A RL++ + G G + IDV AT+ GI V PG N SVAE T L+L+ R +P Sbjct: 70 ADRLKVFGRTGVGYDNIDVAAATERGIAVCPTPGVNRQSVAEHTFALLLSVARGVPGNVT 129 Query: 129 ATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRD--- 185 A AG WP + R++ G T+GL+G G + K V RI L G + H D Sbjct: 130 AVAAG-DWPQV-----SGRELSGATLGLIGLGAIGKAVARIALGFGMRVIAHDPYLDAEA 183 Query: 186 ---TGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVD 242 +G R +L +LLA +D VSLH+ L D +R L+ EAIA MKPGA LVNT+RG +VD Sbjct: 184 VAASGVER-ASLDELLATADFVSLHIFLDDATRHLIDAEAIATMKPGAYLVNTSRGGVVD 242 Query: 243 EXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGV 302 E DV +TEPLP D PL GLDN+++T H+ T ++ R + Sbjct: 243 ETALAAALREGRLSGAGLDVLETEPLPPDSPLRGLDNLIITAHIGAATVESRARSGRMAA 302 Query: 303 ENCRRIRDGEPLAHLVN-EAR 322 + + DG H+VN EAR Sbjct: 303 QAVIDVLDGRTPEHVVNPEAR 323 >tr|A8TU17|A8TU17_9PROT Tax_Id=331869 SubName: Full=2-hydroxyacid dehydrogenase, putative;[alpha proteobacterium BAL199] Length = 321 Score = 161 bits (407), Expect = 1e-37 Identities = 99/257 (38%), Positives = 141/257 (54%), Gaps = 9/257 (3%) Query: 70 PRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRA 129 P+LRLV L AG + D++ A G+ V N GAN+ +V+E VLLMLA R+L + + Sbjct: 65 PKLRLVQLLSAGYDRADLDAARAAGVPVCNNGGANSVAVSEHAVLLMLAVSRQLVRQHLS 124 Query: 130 TRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTR----- 184 +G W + T V ++ G T+G+VG G + K+ R+ A G + R Sbjct: 125 VASGN-WRGNQT--PRVHELRGKTLGIVGLGTIGKKTARLAQAFGMNVTYYDVARLPEDQ 181 Query: 185 -DTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDE 243 D + R+R L +LL+ +D+VSLH PL DT+R L+G +AAMKP A+LVNTARGP+VDE Sbjct: 182 EDLLNVRFRLLRELLSEADVVSLHTPLNDTTRHLIGVAELAAMKPSAILVNTARGPVVDE 241 Query: 244 XXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVE 303 DVFD EP D+PL LDNV+LT H+ T ++ + + Sbjct: 242 TALHAALCDGTIAAAGLDVFDQEPPRPDNPLFSLDNVILTAHLAGPTFESNTARVRNAFD 301 Query: 304 NCRRIRDGEPLAHLVNE 320 N +R+ GE +V E Sbjct: 302 NVQRVARGETPLWIVPE 318 >tr|D3F8A2|D3F8A2_CONWI Tax_Id=469383 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein;[Conexibacter woesei] Length = 308 Score = 159 bits (403), Expect = 4e-37 Identities = 104/274 (37%), Positives = 141/274 (51%), Gaps = 8/274 (2%) Query: 44 FYRELGDADVLW-HVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPG 102 F + +ADVL + + PI + R + + + GAGV+ +DV +A GI VAN+ Sbjct: 35 FRQRAPEADVLLVNAVAPIDSALIATLTRCKAIVRYGAGVDNVDVASAAAAGIQVANVLD 94 Query: 103 ANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNV 162 A+ VA + L LA LRRL + AT G WPT G R + T G+VG G + Sbjct: 95 ASVEEVANHALALALALLRRLRPVHDATARGE-WPTAAVHG--TRRLSALTCGVVGVGRI 151 Query: 163 AKRVERIVLAMGAEQVLHTSTRDTGHPRWRNLP--DLLAASDIVSLHLPLTDTSRGLLGP 220 A+G +V+ + T P W LP DLLA +D+VSLHLPLTD +R LLG Sbjct: 152 GTATAARFEALGL-RVVASDPVVTDAP-WPLLPLADLLAQADVVSLHLPLTDGTRHLLGA 209 Query: 221 EAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNV 280 + AM+PGA+LVN +RG +VDE DVF+ EP+PA HPL Sbjct: 210 AELEAMRPGAILVNVSRGGLVDEAALARQLQRGALGGAGLDVFEDEPIPATHPLCSSPGA 269 Query: 281 VLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPL 314 +LTPH+ WYT + R + R+ G PL Sbjct: 270 LLTPHIAWYTEEAARDVQRKAAQEAARVLTGRPL 303 >tr|D3F4X6|D3F4X6_CONWI Tax_Id=469383 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein;[Conexibacter woesei] Length = 338 Score = 159 bits (403), Expect = 4e-37 Identities = 97/266 (36%), Positives = 135/266 (50%), Gaps = 9/266 (3%) Query: 60 PITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAA 119 P+ L P R V +LG G + IDV AT+ GI VAN+P VA T+ + + Sbjct: 63 PVDASVLANLPDCRFVSRLGIGYDMIDVAAATEAGIPVANVPDYCVEEVAAHTLAFVFSL 122 Query: 120 LRRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVL 179 RRLPQLD RAGR +D GD R G TV ++G+G + RV + ++G + ++ Sbjct: 123 TRRLPQLDAGLRAGRWAASDD--GDGARRPQGTTVAVLGHGRIGARVAQQAASVGFDVLV 180 Query: 180 H------TSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLV 233 H GH L + L +D+VSLH+PLT +R LL A+A M+PG+ LV Sbjct: 181 HDPHVPAERVEAAGHVA-VTLDEALERADVVSLHVPLTPQTRHLLDAPALARMRPGSALV 239 Query: 234 NTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADT 293 NT RG +VDE DVF++EPLPAD PL N++L+PH WY+ Sbjct: 240 NTCRGGLVDETALADALRSGQLGAAALDVFESEPLPADSPLRDAPNLLLSPHAAWYSPIA 299 Query: 294 MRRYLSIGVENCRRIRDGEPLAHLVN 319 + + DG P+ +VN Sbjct: 300 LLELEERAAQQVADFLDGRPVPTIVN 325 >tr|A1HMI9|A1HMI9_9FIRM Tax_Id=401526 SubName: Full=Phosphoglycerate dehydrogenase; EC=1.1.1.95;[Thermosinus carboxydivorans Nor1] Length = 326 Score = 159 bits (403), Expect = 4e-37 Identities = 100/288 (34%), Positives = 153/288 (53%), Gaps = 13/288 (4%) Query: 40 DDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVAN 99 +D+ + L AD L IT + + +AP+L+++ K G GV+ ID+ A LGI VAN Sbjct: 35 NDKEKEQALNSADYFLVALYKITQELIQKAPKLKMIQKTGVGVDNIDLAAAKTLGIPVAN 94 Query: 100 MPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGR--GWPTDPTLGDTVRDIGGCTVGLV 157 PG NA SVAE T+ +++ R++ LDR T+ G W P + ++ G T G++ Sbjct: 95 TPGGNATSVAELTLGMIINLYRKINILDRETKKGNWMSWEFRP----SSYEVKGKTHGII 150 Query: 158 GYGNVAKRVERIVLAMGAEQV------LHTSTRDTGHPRWRNLPDLLAASDIVSLHLPLT 211 G+GN+ + V R+ A G + L + + + L +LL SDI+S+HLPLT Sbjct: 151 GFGNIGREVARLSQAFGTNVIYYDLRRLEPAEEKRLNVTYHELNELLQKSDIISIHLPLT 210 Query: 212 DTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPAD 271 ++ L+ +A +KP A+L+N ARG IVDE DV+ EP+ D Sbjct: 211 PDTKNLISERELALLKPTALLINVARGNIVDEVALYRALKENKLLGAGIDVWSKEPV-ED 269 Query: 272 HPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 +PLL L+NV+ TPH+ T DT++ L + EN G+ +VN Sbjct: 270 NPLLTLNNVLATPHIGAGTRDTLQTVLGLAFENIIATTRGKNPRFVVN 317 >tr|D0WLS2|D0WLS2_9ACTO Tax_Id=649743 SubName: Full=Phosphoglycerate dehydrogenase;[Actinomyces sp. oral taxon 848 str. F0332] Length = 404 Score = 159 bits (402), Expect = 5e-37 Identities = 106/298 (35%), Positives = 153/298 (51%), Gaps = 6/298 (2%) Query: 26 PHLDWLDVRFCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTI 85 P D DVR ++DE L DV + P T + +P L+LV G + Sbjct: 40 PFRDIGDVREAAGDEDELI-EALDGCDVAFSHTFPFTEKVVAASPSLKLVTVCRGGPVNV 98 Query: 86 DVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDT 145 ++E AT+ G+LV+ PG NA + AE TV ++LA+LR++PQ R G+ W +D + D Sbjct: 99 NIEAATRAGVLVSYTPGRNATATAEHTVGMILASLRQIPQRHREVIDGQ-WRSDYYIFDN 157 Query: 146 V-RDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTSTRD---TGHPRWRNLPDLLAAS 201 V +IG TVG+VGYG V +RV ++ A GA +++ D G R +L +LLA S Sbjct: 158 VGAEIGSSTVGVVGYGAVGRRVAAVMAAFGARVLVYDPWADEPAEGMTRVDSLGELLAGS 217 Query: 202 DIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXD 261 D+V++H +T +RG++ +A+A M G+VLVN ARG +VD D Sbjct: 218 DVVTIHARVTAENRGMIDADALALMPEGSVLVNCARGELVDYDAVCDALDSGHLFAAGFD 277 Query: 262 VFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 V EPLP H LL V +TPH+ + + R IG E+ G HL N Sbjct: 278 VLPQEPLPPGHRLLRTPRVTITPHLAGASKEAARIAARIGAEDIAAFAVGRRPLHLAN 335 >tr|D0DAV5|D0DAV5_9RHOB Tax_Id=501479 SubName: Full=D-3-phosphoglycerate dehydrogenase; EC=1.1.1.95;[Citreicella sp. SE45] Length = 336 Score = 158 bits (400), Expect = 8e-37 Identities = 96/256 (37%), Positives = 140/256 (54%), Gaps = 10/256 (3%) Query: 66 LNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQ 125 ++ AP+L+++ K G GV+ ID++ A + GI V GANA SVAE + L+LAA++R+ Sbjct: 63 MDAAPQLKVISKHGVGVDNIDIQAAAERGIPVLVATGANAVSVAEHAIALLLAAVKRILP 122 Query: 126 LDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLH----- 180 LD RAGR W G + +I T+GL+G G +A+ R+ +G + + Sbjct: 123 LDAGLRAGR-WEKP---GFSGHEIAESTMGLMGMGAIAQATGRMAKGLGLHLLGYDPYAP 178 Query: 181 -TSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGP 239 ++ + G R + DLLA SDI+SLH PLT+ +RGLL E+IA M GA ++NTARG Sbjct: 179 DSAFEELGVTRCETVEDLLAGSDILSLHCPLTEQTRGLLNAESIAQMPKGAYVINTARGG 238 Query: 240 IVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLS 299 ++DE D F +EP ADHP + +VLTPH+ T R Sbjct: 239 LIDEAALVAAIQSGHLAGAGLDTFASEPPAADHPFFAVPEIVLTPHIGGVTRQAGARVGV 298 Query: 300 IGVENCRRIRDGEPLA 315 V +I DG+P+A Sbjct: 299 DAVRGIFQILDGQPVA 314 >tr|D3ICZ0|D3ICZ0_9BACT Tax_Id=575614 SubName: Full=Glycerate dehydrogenase;[Prevotella sp. oral taxon 299 str. F0039] Length = 318 Score = 158 bits (399), Expect = 1e-36 Identities = 95/270 (35%), Positives = 146/270 (54%), Gaps = 7/270 (2%) Query: 50 DADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVA 109 DA+++ P+ + L + P+L+ + L G N +DV+ A +LGI V N+P + SVA Sbjct: 44 DAEMILLNKVPMKEETLLQLPKLKYIGVLATGFNIVDVDAAKRLGIAVTNIPNYSTDSVA 103 Query: 110 EGTVLLMLAALRRLPQLDRATRAGRGWP--TDPTLGDT-VRDIGGCTVGLVGYGNVAKRV 166 + +L ++ R GR W +D DT ++++ G T+G++G GN+ KRV Sbjct: 104 QTAFAHILNITNKVDYYACENRKGR-WSQQSDFCYIDTPIQELTGKTLGVIGLGNIGKRV 162 Query: 167 ERIVLAMGAEQVLHTSTRDTGHPRW---RNLPDLLAASDIVSLHLPLTDTSRGLLGPEAI 223 I LA G + + TS + P +L DLL+ SDIVSLH PLTDT+R ++ + + Sbjct: 163 ADIALAFGLKVKVFTSKKAEDLPTGIEKASLNDLLSTSDIVSLHCPLTDTTREMINKDTL 222 Query: 224 AAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLT 283 + MKP A+LVNT+RGP+V+E DV EP AD+PL +N +T Sbjct: 223 SIMKPNAILVNTSRGPLVNEHDIAEALHSKLIAAYAADVMCKEPPAADNPLFRCENAYIT 282 Query: 284 PHVTWYTADTMRRYLSIGVENCRRIRDGEP 313 PHV W + + + R L I + N + +G P Sbjct: 283 PHVAWASTEALGRLLDIALSNAKAFINGNP 312 >tr|A4AC31|A4AC31_9GAMM Tax_Id=314285 SubName: Full=Glycerate dehydrogenase;[Congregibacter litoralis KT71] Length = 323 Score = 158 bits (399), Expect = 1e-36 Identities = 98/254 (38%), Positives = 132/254 (51%), Gaps = 5/254 (1%) Query: 70 PRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRA 129 P+LR + + GV+ IDV+ AT GI+V N PG + A+ + L+LAA RRL + DR Sbjct: 65 PQLRFIASMSVGVDHIDVKAATARGIVVGNTPGVLVETTADASFALLLAAARRLVEADRF 124 Query: 130 TRAGRGWPTDPTLGD---TVRDIGGCTVGLVGYGNVAKRVERIVLAMGAEQVLHTST-RD 185 R G W + T +D+ G T+G+VG G V + V R G + + T R+ Sbjct: 125 VRGGH-WRVENAWSPEFFTGKDVAGATLGIVGLGEVGQAVARRAAGFGMKVLAWNRTPRN 183 Query: 186 TGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXX 245 L +LLAASD VS++L L + +R L+ +A MK AVLVNT+RG IVDE Sbjct: 184 VPGVEAVELDELLAASDFVSINLALGEETRNLIDERRLALMKRDAVLVNTSRGGIVDEQA 243 Query: 246 XXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENC 305 DVF+ EP+P DHPLL L NVV TPH+ T T + + N Sbjct: 244 LADALSHDRLAAAGLDVFEREPVPEDHPLLSLPNVVATPHIGSATEATRIKMADMAALNM 303 Query: 306 RRIRDGEPLAHLVN 319 GEP+ H VN Sbjct: 304 LEALRGEPMPHCVN 317 >tr|Q8TYK0|Q8TYK0_METKA Tax_Id=2320 SubName: Full=Predicted dehydrogenase related to phosphoglycerate dehydrogenase;[Methanopyrus kandleri] Length = 522 Score = 157 bits (398), Expect = 1e-36 Identities = 102/290 (35%), Positives = 150/290 (51%), Gaps = 13/290 (4%) Query: 38 EEDDETFYRELGDADVLWHVLRP--ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGI 95 + D+E + DAD W V +T + + A L+++ + G GV+ IDV+ AT+ GI Sbjct: 29 DADEEEIREHVRDADA-WVVRSGTRVTRELIEEAKNLKVIARAGVGVDNIDVKAATERGI 87 Query: 96 LVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVG 155 +V N P +++ SVAE T+ L+LA R++PQ DR+ R G W +G ++ G T+G Sbjct: 88 IVVNAPESSSISVAEHTMGLILALARKIPQADRSVRRGE-WDRKRFMG---VELAGKTLG 143 Query: 156 LVGYGNVAKRVERIVLAMGAEQVLHTS------TRDTGHPRWRNLPDLLAASDIVSLHLP 209 L+G G + ++V + A E + + G L +LL +D+VS+H+P Sbjct: 144 LIGLGRIGQQVAKRAKAFEMEVTAYDPYIPEKVAEELGVELVDELEELLERADVVSIHVP 203 Query: 210 LTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLP 269 LT+ + G++G E + MK A LVN ARG IVDE DVF EP Sbjct: 204 LTEETEGMIGEEELKRMKSSAFLVNCARGKIVDEEALIKALKEGWIAGAALDVFAEEPPG 263 Query: 270 ADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 DHPL LDNVVLTPH+ T + R I R+ GE ++VN Sbjct: 264 EDHPLYELDNVVLTPHIGGSTGEAQRAAGLIVAREIERVLKGEIPENVVN 313 >tr|Q986P2|Q986P2_RHILO Tax_Id=381 SubName: Full=Phosphoglycerate dehydrogenase;[Rhizobium loti] Length = 330 Score = 157 bits (397), Expect = 2e-36 Identities = 103/274 (37%), Positives = 143/274 (52%), Gaps = 10/274 (3%) Query: 48 LGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPS 107 +GDA++L L P++ + R P L+LV G ID+ A GI V N+PG NA + Sbjct: 54 IGDAEILVTQLAPLSEAMMRRLPALKLVAVSRGGPINIDMAAARAHGITVVNVPGRNATA 113 Query: 108 VAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGD-TVRDIGGCTVGLVGYGNVAKRV 166 VAE T+ +LA R + A R G W D D T R++ TVG++GYGN+ +V Sbjct: 114 VAEFTLGAILAETRLIRVGHEALRKGE-WRGDLYRADRTGRELSEMTVGVIGYGNIGTKV 172 Query: 167 ERIVLAMGAEQV-------LHTSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLG 219 R++ A G + L R+ G L +LLA SD+V+LH +T+ +RGL+G Sbjct: 173 VRLLRAFGCHVLVSDPYVQLSAEDRNAG-VELVALDNLLARSDVVTLHPRVTEETRGLIG 231 Query: 220 PEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDN 279 +AIA MKPG +L+NTARGP+VD + F EP+P+D PLL L N Sbjct: 232 KDAIALMKPGVILINTARGPLVDYDALYEALVSGQIASAMLETFAVEPVPSDWPLLQLPN 291 Query: 280 VVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEP 313 V LTPH+ + T+ E RR G P Sbjct: 292 VTLTPHIAGASVRTVTYAAEQAAEEVRRYLTGLP 325 >tr|B8DYJ5|B8DYJ5_DICTD Tax_Id=515635 SubName: Full=D-3-phosphoglycerate dehydrogenase; EC=1.1.1.95;[Dictyoglomus turgidum] Length = 525 Score = 157 bits (396), Expect = 2e-36 Identities = 100/265 (37%), Positives = 141/265 (53%), Gaps = 10/265 (3%) Query: 61 ITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAAL 120 +T D + RA L+++ + G GV+ IDVE AT+ GILV N P N + E T+ LMLA Sbjct: 55 VTKDVIERAKNLKVIGRAGVGVDNIDVEEATRKGILVINAPEGNTIAACEHTIGLMLAIS 114 Query: 121 RRLPQLDRATRAGRGWPTDPTLGDTVRDIGGCTVGLVGYG----NVAKRVERIVLAMGAE 176 R++PQ R G+ W +G+ ++ G T+GLVG G VAKR + + + A Sbjct: 115 RKIPQAFSLLRQGK-WERKSFIGN---ELYGKTLGLVGLGRIGSEVAKRAKSFKMRVIAY 170 Query: 177 Q--VLHTSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIAAMKPGAVLVN 234 + ++ + +LP LL +D VSLHLPLT ++ L+G + + MKP A L+N Sbjct: 171 DPFISPEKAKELDVELYSDLPALLKEADYVSLHLPLTQDTKNLIGKKELEMMKPTAYLIN 230 Query: 235 TARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTPHVTWYTADTM 294 ARG +VDE DVF EP+ D+PLL LDNVVLTPH+ T + Sbjct: 231 CARGGLVDEDALYEILKEKKIAGAALDVFKNEPINPDNPLLTLDNVVLTPHLGASTQEAQ 290 Query: 295 RRYLSIGVENCRRIRDGEPLAHLVN 319 + I E R GE ++H VN Sbjct: 291 EKVALIVAEEIIRFFKGEMVSHAVN 315 >tr|D2QPL3|D2QPL3_SPILD Tax_Id=504472 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein;[Spirosoma linguale] Length = 318 Score = 156 bits (395), Expect = 3e-36 Identities = 88/272 (32%), Positives = 144/272 (52%), Gaps = 8/272 (2%) Query: 50 DADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVA 109 DAD+++ P+ L++ P L+ + L G N +D+ TA + G++V+N+PG PSV Sbjct: 44 DADIVFTNKTPLDAATLDQLPNLKFISVLATGFNIVDIATAKKKGVVVSNVPGYGTPSVV 103 Query: 110 EGTVLLMLAALRRLPQLDRATRAGRGWP--TDPTLGD-TVRDIGGCTVGLVGYGNVAKRV 166 + T L+L + + + R G+ W D D + ++ G T+G++G+G++ ++V Sbjct: 104 QLTFALLLELTLHVQRHSDSVRDGK-WARSVDFCFWDYPLIELAGKTMGIIGFGSIGEKV 162 Query: 167 ERIVLAMGAEQVLHTSTR-DTGHP---RWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEA 222 + A G + R D H +W +P+LLA SD+VS+H PL ++GL+ E Sbjct: 163 ADVATAFGMNIIGSKRHRTDQSHRPNFKWAEIPELLAESDVVSIHTPLVPETQGLINKEN 222 Query: 223 IAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVL 282 +A MKP A L+NT+RGPI+ + DV EP D+PL N ++ Sbjct: 223 LALMKPSAFLLNTSRGPIIVDQDLADALNNGVIAGAGIDVLSKEPPLPDNPLFTAKNCLI 282 Query: 283 TPHVTWYTADTMRRYLSIGVENCRRIRDGEPL 314 TPH+ W T + R ++I VEN DG+P+ Sbjct: 283 TPHIAWATTEARARLMAITVENLAAFLDGKPV 314 >tr|A4YX94|A4YX94_BRASO Tax_Id=114615 SubName: Full=Putative D-3-phosphoglycerate dehydrogenase; EC=1.1.1.95;[Bradyrhizobium sp.] Length = 346 Score = 156 bits (394), Expect = 4e-36 Identities = 104/287 (36%), Positives = 148/287 (51%), Gaps = 12/287 (4%) Query: 35 FCGEEDDETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLG 94 F G+ D+ + +G+A +L L PI+ L R PRL+ + G +D++ A G Sbjct: 59 FMGDPDELADF--IGEAPLLVTHLAPISRAMLQRLPRLKFIAVSRGGPVNVDMQAARDHG 116 Query: 95 ILVANMPGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPTLGD-TVRDIGGCT 153 +LV N PG NA +VAE T+ MLA R + + R G W D D T R++G T Sbjct: 117 VLVVNTPGRNASAVAEFTIGAMLAETRLIRSGHESMRGGE-WRGDLYRADRTGRELGEMT 175 Query: 154 VGLVGYGNVAKRVERIVLAMGAEQVLHTSTRDTGHPRWRN-------LPDLLAASDIVSL 206 VG+VGYG + RV +++ A G ++L T + RN L +LL+ +D++SL Sbjct: 176 VGIVGYGAIGTRVVKLLKAFGC-RILVTDPYVQLTAQDRNDGVEHVALAELLSRADVISL 234 Query: 207 HLPLTDTSRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTE 266 H +T + G + EA+A +KPGA+L+NTARGP+VD D F E Sbjct: 235 HARVTSETTGFIDREALARIKPGAILINTARGPLVDYKALFEVLSSGRLAGAMLDTFAIE 294 Query: 267 PLPADHPLLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEP 313 P+P D PLL L NV LTPH+ + T+ E RR GEP Sbjct: 295 PVPPDWPLLQLPNVTLTPHIAGASVRTVTIAADQAAEEVRRYLAGEP 341 >tr|C5EEM4|C5EEM4_9FIRM Tax_Id=457421 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase;[Clostridiales bacterium 1_7_47FAA] Length = 319 Score = 156 bits (394), Expect = 4e-36 Identities = 83/280 (29%), Positives = 145/280 (51%), Gaps = 8/280 (2%) Query: 41 DETFYRELGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANM 100 +E +GDA ++ PIT + +++ P ++ + L G N ID E A + GI+V+N+ Sbjct: 35 EEKVVERIGDAQAVYTNKTPITAETIHKCPDMKFIGVLATGYNVIDTEAAKEQGIVVSNI 94 Query: 101 PGANAPSVAEGTVLLMLAALRRLPQLDRATRAGRGWPTDPT---LGDTVRDIGGCTVGLV 157 P +VA+ T+ L+L + + +AG W + + ++ G G++ Sbjct: 95 PSYGTDAVAQYTMALLLELCHHVDEHSNCVKAGE-WSNNQDWCFWKHPLVELAGKNFGVI 153 Query: 158 GYGNVAKRVERIVLAMGAEQVLHTSTRD----TGHPRWRNLPDLLAASDIVSLHLPLTDT 213 G+G + +R I A G + + D T R+ +L LLA SD++SLH PL + Sbjct: 154 GFGRIGRRTAEIAQAFGMKVLAFDEYPDKALETEKCRYVSLDRLLAESDVISLHCPLFPS 213 Query: 214 SRGLLGPEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHP 273 + G++ + IA MK G ++NT+RGP++ E DV +EP+ D+P Sbjct: 214 TEGIINKDTIAKMKDGVKILNTSRGPLIVEEDLKEALNSGKVSGAAVDVVSSEPIREDNP 273 Query: 274 LLGLDNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEP 313 L+G N+++TPH+ W ++ +R + I V+N R+ DG+P Sbjct: 274 LMGAKNMIITPHIAWAPRESRQRLMDIAVDNLRKFVDGKP 313 >tr|A8S7W6|A8S7W6_9FIRM Tax_Id=411485 SubName: Full=Putative uncharacterized protein;[Faecalibacterium prausnitzii M21/2] Length = 320 Score = 156 bits (394), Expect = 4e-36 Identities = 99/272 (36%), Positives = 144/272 (52%), Gaps = 8/272 (2%) Query: 48 LGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPS 107 +GDA++++ I L + P L+ V + G + ID+E + G+ VAN+PG + S Sbjct: 43 IGDAELVFINKCRIDEAVLAQCPNLKWVGIIATGTDNIDLEACRRHGVAVANVPGYSTYS 102 Query: 108 VAEGTVLLMLAALRRLPQLDRATRAGR---GWPTDPTLGDTVRDIGGCTVGLVGYGNVAK 164 VA+ T L+LA + + DRA +AG G P + L V ++ G T G+ GYG++ + Sbjct: 103 VAQMTFSLLLAICQCAQRYDRAVKAGYWQLGIPAEYGLLPQV-ELLGKTFGIYGYGSIGR 161 Query: 165 RVERIVLAMGAEQVLHTST----RDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLGP 220 + RI A G E ++ T T D + + LLA SD++SLH P T +RGL+ Sbjct: 162 QTARIAKAFGMEVLVCTRTVRPEYDADGVEFVDFDTLLARSDVLSLHCPATPETRGLISR 221 Query: 221 EAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNV 280 EA+A MKPGA+L+NTARG +VDE D F TEPLP L L Sbjct: 222 EALAKMKPGAILLNTARGALVDEEAVADALESGKLAFYGADAFATEPLPPQSRLRSLPGA 281 Query: 281 VLTPHVTWYTADTMRRYLSIGVENCRRIRDGE 312 VLTPH+ W T + ++R + I N R G+ Sbjct: 282 VLTPHIAWTTKEALQRLMDITTGNLRSFLAGK 313 >tr|A6W4F1|A6W4F1_KINRD Tax_Id=266940 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding;[Kineococcus radiotolerans] Length = 326 Score = 155 bits (393), Expect = 5e-36 Identities = 98/275 (35%), Positives = 137/275 (49%), Gaps = 11/275 (4%) Query: 51 ADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAE 110 AD L + D L+ P +R V + G GV+T+DV+ T G+ V N+P SV++ Sbjct: 45 ADALVVQYARVDADLLDALPTVRAVGRYGVGVDTVDVDACTARGVAVCNVPDYGTESVSD 104 Query: 111 GTVLLMLAALRRLPQLDRATRAGRG--WPTDPTLGDTVRDIGGCTVGLVGYGNVAKRVER 168 + L LAA RR+ +DR RAG G P P V GG G+VG G + R Sbjct: 105 HAIALALAAARRIAWMDRRVRAGAGELAPLRP-----VHQFGGRVFGVVGLGLIGAATAR 159 Query: 169 IVLAMGAEQVLHTSTRDTGHP----RWRNLPDLLAASDIVSLHLPLTDTSRGLLGPEAIA 224 +G V + R G L DLLA + +VSLH+PLT+ +R L+G +A Sbjct: 160 KAAGLGYRVVATDARRAPGTTVDGVEVVTLDDLLARAHVVSLHVPLTEGTRHLIGAAELA 219 Query: 225 AMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLPADHPLLGLDNVVLTP 284 M+P AV+VNT+RG ++D DVF+ EPLP HPL LD VLTP Sbjct: 220 RMRPDAVVVNTSRGGVLDTAALADALRAGRLHGAGLDVFEEEPLPPGHPLATLDTAVLTP 279 Query: 285 HVTWYTADTMRRYLSIGVENCRRIRDGEPLAHLVN 319 H+ WY+ ++ V+N + G P A ++N Sbjct: 280 HLAWYSEESYGELKRRTVQNVVDVCAGRPPADVLN 314 >tr|C8SFV5|C8SFV5_9RHIZ Tax_Id=536019 SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding;[Mesorhizobium opportunistum WSM2075] Length = 336 Score = 155 bits (393), Expect = 5e-36 Identities = 99/279 (35%), Positives = 146/279 (52%), Gaps = 15/279 (5%) Query: 48 LGDADVLWHVLRPITGDDLNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPS 107 + DAD+L PIT + AP+L+ + K G G++ ID+ A Q GI V N+P + Sbjct: 42 VADADLLLMCYTPITARVIEAAPKLKGIVKYGVGIDAIDIPAAMQRGIPVVNVPEYAEET 101 Query: 108 VAEGTVLLMLAALRRLPQLDRA-TRAGRGWPTDPTLGDTVRDIGGCTVGLVGYGNVAKRV 166 VAEG LM+A +RLP + A +R G WP LG RDI G T+GLVG G + + + Sbjct: 102 VAEGAFALMIALAKRLPAITAAVSRDGWIWPEQRWLG---RDISGATLGLVGCGKIGRSM 158 Query: 167 ERIVLAMGAEQVL-------HTSTRDTGHPRWRNLPDLLAASDIVSLHLPLTDTSRGLLG 219 R+ +VL + + G + +L +L ASD VS+H L +RGL+G Sbjct: 159 ARMAGQGFRARVLGFDPGVDAAAMQGAGIEKAHDLQAMLRASDFVSIHCVLNYNTRGLIG 218 Query: 220 PEAIAAMKPGAVLVNTARGPIVDEXXXXXXXXXXXXXXXXXDVFDTEPLP-ADHPLLGL- 277 +A ++P AV+VN +RG ++DE DV+ EPL + HP+ L Sbjct: 219 KAELACLRPSAVVVNVSRGALIDETALVEAIVAGRIGGAGLDVYSVEPLARSGHPMSALF 278 Query: 278 --DNVVLTPHVTWYTADTMRRYLSIGVENCRRIRDGEPL 314 D+V+L PH+T++T + MRR + C I DG P+ Sbjct: 279 DRDDVILFPHLTFFTQEAMRRLEDDTLARCFEILDGRPV 317 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.321 0.139 0.427 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 2,701,493,401 Number of extensions: 113213421 Number of successful extensions: 275899 Number of sequences better than 10.0: 9699 Number of HSP's gapped: 254864 Number of HSP's successfully gapped: 9733 Length of query: 322 Length of database: 4,236,830,644 Length adjustment: 138 Effective length of query: 184 Effective length of database: 2,510,745,412 Effective search space: 461977155808 Effective search space used: 461977155808 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 81 (35.8 bits)