BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_1498 (506 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|A0QSJ2|A0QSJ2_MYCS2 Tax_Id=246196 (mmsA)SubName: Full=Methylm... 959 0.0 tr|A4TEF3|A4TEF3_MYCGI Tax_Id=350054 SubName: Full=Methylmalonat... 884 0.0 tr|A1T4U6|A1T4U6_MYCVP Tax_Id=350058 SubName: Full=Methylmalonat... 876 0.0 tr|D5PCF5|D5PCF5_9MYCO Tax_Id=525368 (mmsA)SubName: Full=Methylm... 864 0.0 tr|Q1BD56|Q1BD56_MYCSS Tax_Id=164756 SubName: Full=Methylmalonat... 859 0.0 tr|A3PVH1|A3PVH1_MYCSJ Tax_Id=164757 SubName: Full=Methylmalonat... 859 0.0 tr|A1UBT6|A1UBT6_MYCSK Tax_Id=189918 SubName: Full=Methylmalonat... 859 0.0 tr|B2HCW3|B2HCW3_MYCMM Tax_Id=216594 (mmsA)SubName: Full=Methylm... 854 0.0 tr|A0PMA6|A0PMA6_MYCUA Tax_Id=362242 (mmsA)SubName: Full=Methylm... 853 0.0 tr|Q73S61|Q73S61_MYCPA Tax_Id=1770 (mmsA)SubName: Full=MmsA;[Myc... 841 0.0 tr|A0QKW4|A0QKW4_MYCA1 Tax_Id=243243 (mmsA)SubName: Full=Methylm... 839 0.0 tr|A0QFM5|A0QFM5_MYCA1 Tax_Id=243243 (mmsA)SubName: Full=Methylm... 836 0.0 tr|A2VG55|A2VG55_MYCTU Tax_Id=348776 SubName: Full=Methylmalonat... 830 0.0 tr|O53816|O53816_MYCTU Tax_Id=1773 (mmsA)SubName: Full=PROBABLE ... 829 0.0 tr|C6DUS0|C6DUS0_MYCTK Tax_Id=478434 SubName: Full=Methylmalonat... 829 0.0 tr|C1AL88|C1AL88_MYCBT Tax_Id=561275 (mmsA)SubName: Full=Putativ... 829 0.0 tr|A5WKC1|A5WKC1_MYCTF Tax_Id=336982 SubName: Full=Methylmalonat... 829 0.0 tr|A5U0E0|A5U0E0_MYCTA Tax_Id=419947 (mmsA)SubName: Full=Putativ... 829 0.0 tr|A1KGN5|A1KGN5_MYCBP Tax_Id=410289 (mmsA)SubName: Full=Probabl... 829 0.0 tr|D6G0J2|D6G0J2_MYCTU Tax_Id=478435 SubName: Full=Methylmalonat... 829 0.0 tr|D6FER8|D6FER8_MYCTU Tax_Id=611303 SubName: Full=Methylmalonat... 829 0.0 tr|D6F223|D6F223_MYCTU Tax_Id=611302 SubName: Full=Methylmalonat... 829 0.0 tr|D5ZDF6|D5ZDF6_MYCTU Tax_Id=537210 SubName: Full=Methylmalonat... 829 0.0 tr|D5Z0Y6|D5Z0Y6_MYCTU Tax_Id=537209 SubName: Full=Methylmalonat... 829 0.0 tr|D5YP48|D5YP48_MYCTU Tax_Id=515616 SubName: Full=Methylmalonat... 829 0.0 tr|D5YBM7|D5YBM7_MYCTU Tax_Id=520140 SubName: Full=Methylmalonat... 829 0.0 tr|D5Y182|D5Y182_MYCTU Tax_Id=520141 SubName: Full=Methylmalonat... 829 0.0 tr|D5XR38|D5XR38_MYCTU Tax_Id=515617 SubName: Full=Methylmalonat... 829 0.0 tr|A4KF68|A4KF68_MYCTU Tax_Id=395095 SubName: Full=Methylmalonat... 829 0.0 tr|Q7D9C1|Q7D9C1_MYCTU Tax_Id=1773 (mmsA)SubName: Full=Methylmal... 827 0.0 tr|Q7U1C7|Q7U1C7_MYCBO Tax_Id=1765 (mmsA)SubName: Full=PROBABLE ... 826 0.0 tr|D5UUU4|D5UUU4_TSUPA Tax_Id=521096 SubName: Full=Methylmalonat... 815 0.0 tr|D0L3S5|D0L3S5_GORB4 Tax_Id=526226 SubName: Full=Methylmalonat... 806 0.0 tr|A4F9Q3|A4F9Q3_SACEN Tax_Id=405948 (mmsA2)SubName: Full=Methyl... 722 0.0 tr|D5PVL2|D5PVL2_COREQ Tax_Id=525370 (mmsA2)SubName: Full=Methyl... 716 0.0 tr|C1AW62|C1AW62_RHOOB Tax_Id=632772 (mmsA)SubName: Full=Methylm... 702 0.0 tr|Q0SGI1|Q0SGI1_RHOSR Tax_Id=101510 (mmsA2)SubName: Full=Methyl... 701 0.0 tr|D1CZJ7|D1CZJ7_9RHIZ Tax_Id=520449 SubName: Full=Methylmalonat... 700 0.0 tr|A8IML5|A8IML5_AZOC5 Tax_Id=438753 SubName: Full=Methylmalonat... 699 0.0 tr|A4YSQ9|A4YSQ9_BRASO Tax_Id=114615 SubName: Full=Methylmalonat... 699 0.0 tr|B1LX55|B1LX55_METRJ Tax_Id=426355 SubName: Full=Methylmalonat... 698 0.0 tr|A9M869|A9M869_BRUC2 Tax_Id=483179 (mmsA)SubName: Full=Methylm... 698 0.0 tr|D0BJ29|D0BJ29_BRUSU Tax_Id=520488 SubName: Full=ATP/GTP-bindi... 698 0.0 tr|Q8FYN3|Q8FYN3_BRUSU Tax_Id=29461 (mmsA)SubName: Full=Methylma... 697 0.0 tr|C0G8L3|C0G8L3_9RHIZ Tax_Id=595497 (mmsA)SubName: Full=Methylm... 697 0.0 >tr|A0QSJ2|A0QSJ2_MYCS2 Tax_Id=246196 (mmsA)SubName: Full=Methylmalonate-semialdehyde dehydrogenase; EC=1.2.1.27;[Mycobacterium smegmatis] Length = 506 Score = 959 bits (2479), Expect = 0.0 Identities = 482/506 (95%), Positives = 482/506 (95%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQIQHFINGRRTSAGSTRTADVMNPSTG QKEWAA Sbjct: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGEVQAQVLLASAADVDAAVTGAAEAQKEWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL Sbjct: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP Sbjct: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA Sbjct: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR Sbjct: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL Sbjct: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG Sbjct: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY Sbjct: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 TKTKTVTERWPSGIKDGAEFVIPTMK Sbjct: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 >tr|A4TEF3|A4TEF3_MYCGI Tax_Id=350054 SubName: Full=Methylmalonate-semialdehyde dehydrogenase (Acylating); EC=1.2.1.27;[Mycobacterium gilvum] Length = 506 Score = 884 bits (2285), Expect = 0.0 Identities = 442/506 (87%), Positives = 457/506 (90%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTT+I HFI+G+R+ STRTA V+NPSTG QKEWAA Sbjct: 1 MTTRIPHFIDGKRSELASTRTAGVLNPSTGEVQSEVLLASAADVDTAVASAVEAQKEWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARV MKFI LVN + DELA LLSIEHGKTVADS GDIQRGIEVIEFA+GIPHLL Sbjct: 61 WNPQRRARVFMKFIQLVNDHVDELAELLSIEHGKTVADSKGDIQRGIEVIEFAIGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGEFTE AGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP Sbjct: 121 KGEFTENAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVP+RLAELF+EAGLP GVFQVVQGDKEAVDAILTHP +QAVGFVGSSDIAQYIYSTAAA Sbjct: 181 SVPLRLAELFLEAGLPAGVFQVVQGDKEAVDAILTHPDIQAVGFVGSSDIAQYIYSTAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR Sbjct: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 RL ERV QLRVGHSLDPKADYGPLVT AAL RV+DYIGQGVEAGAELVVDGRERATDEL Sbjct: 301 NRLVERVNQLRVGHSLDPKADYGPLVTGAALERVRDYIGQGVEAGAELVVDGRERATDEL 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 +FDDQ L GYFIGPTLFDHV TDMSIYTDEIFGPVLCIVRA DY+EALSLPTKHEYGNG Sbjct: 361 SFDDQDLSKGYFIGPTLFDHVTTDMSIYTDEIFGPVLCIVRAADYDEALSLPTKHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGDAARDFVS+VQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY Sbjct: 421 VAIFTRDGDAARDFVSKVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 TK KTVTERWPSGIKDGAEFVIPTMK Sbjct: 481 TKVKTVTERWPSGIKDGAEFVIPTMK 506 >tr|A1T4U6|A1T4U6_MYCVP Tax_Id=350058 SubName: Full=Methylmalonate-semialdehyde dehydrogenase (Acylating); EC=1.2.1.27;[Mycobacterium vanbaalenii] Length = 534 Score = 876 bits (2263), Expect = 0.0 Identities = 436/506 (86%), Positives = 457/506 (90%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTT+I HFI+G+R+ STRTADV+NPSTG QKEWAA Sbjct: 29 MTTRIPHFIDGKRSDLSSTRTADVLNPSTGAVQAEVLLASAADVDTAVASAVEAQKEWAA 88 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARV+MKFI+LVN N DELA LLSIEHGKTV D+ GDIQRGIEVIEFA+GIPHLL Sbjct: 89 WNPQRRARVMMKFIELVNANIDELAELLSIEHGKTVPDAKGDIQRGIEVIEFAIGIPHLL 148 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGEFTEGAG+GIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP Sbjct: 149 KGEFTEGAGSGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 208 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELF+EAGLP GVFQVV GDKEAVDAILTHP +QAVGFVGSSDIAQYIYSTAAA Sbjct: 209 SVPVRLAELFLEAGLPAGVFQVVHGDKEAVDAILTHPDIQAVGFVGSSDIAQYIYSTAAA 268 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 +GKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR Sbjct: 269 NGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 328 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 RL ERV QLRVGHSLDPKADYGPLVT AAL RV+DYIGQGV+AGAELVVDGRER TDEL Sbjct: 329 NRLVERVNQLRVGHSLDPKADYGPLVTGAALERVRDYIGQGVDAGAELVVDGRERTTDEL 388 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 +FDDQ L G+FIGPTLFDHV TDMSIYT EIFGPVLCIVRA DY+EALSLP+KHEYGNG Sbjct: 389 SFDDQDLSKGFFIGPTLFDHVTTDMSIYTGEIFGPVLCIVRAKDYDEALSLPSKHEYGNG 448 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGDAARDFVS+VQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY Sbjct: 449 VAIFTRDGDAARDFVSKVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 508 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 TK KTVTERWPSGIKDGAEFVIPTMK Sbjct: 509 TKVKTVTERWPSGIKDGAEFVIPTMK 534 >tr|D5PCF5|D5PCF5_9MYCO Tax_Id=525368 (mmsA)SubName: Full=Methylmalonic acid semialdehyde dehydrogenase; EC=1.2.1.27;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 506 Score = 864 bits (2232), Expect = 0.0 Identities = 424/505 (83%), Positives = 456/505 (90%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STRTADV NPSTG QK WAA Sbjct: 1 MTTQIPHFIDGQRTAGRSTRTADVFNPSTGEVQSRVPMAGKADIDAAVASAAEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARV+M+FI+LVN++ DELA LLS+EHGKTVADS GD+QRGIEVIEFA+GIPHLL Sbjct: 61 WNPQRRARVMMRFIELVNEHMDELAELLSLEHGKTVADSRGDVQRGIEVIEFAIGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELF+EAGLPPGVFQVV GDKEAVD IL HP +QAVGFVGSSDIAQYIY+TAAA Sbjct: 181 SVPVRLAELFVEAGLPPGVFQVVHGDKEAVDTILHHPDIQAVGFVGSSDIAQYIYATAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKRSQCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGE+TANRLR Sbjct: 241 TGKRSQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEQTANRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL +R+ LRVGHSLDPKADYGPLVTEAAL RV++YIGQGVEAGAELV+DGRERA+D+L Sbjct: 301 ARLIDRINNLRVGHSLDPKADYGPLVTEAALARVRNYIGQGVEAGAELVIDGRERASDDL 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 TF D +LEGG+FIGPTLFDHV DMSIYTDEIFGPVLCIVRAHDYEEALSLP++HEYGNG Sbjct: 361 TFGDANLEGGFFIGPTLFDHVTPDMSIYTDEIFGPVLCIVRAHDYEEALSLPSEHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPV+YHTFGGWKRSGFGDLNQHGP SI FY Sbjct: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVSYHTFGGWKRSGFGDLNQHGPHSILFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTM 505 TKTKTVT RWPSGIKDGAEFVIPTM Sbjct: 481 TKTKTVTSRWPSGIKDGAEFVIPTM 505 >tr|Q1BD56|Q1BD56_MYCSS Tax_Id=164756 SubName: Full=Methylmalonate-semialdehyde dehydrogenase (Acylating); EC=1.2.1.27;[Mycobacterium sp.] Length = 506 Score = 859 bits (2219), Expect = 0.0 Identities = 424/506 (83%), Positives = 453/506 (89%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MT QIQHFING+RT+ STRTADVMNPSTG QKEWAA Sbjct: 1 MTNQIQHFINGKRTAGESTRTADVMNPSTGAVQAQVLLGSRADVDAAVAGAAEAQKEWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARV+M+FI+LVNQ+ DELA LLSIEHGKTV D+ GDIQRGIEVIEFA+GIPHL+ Sbjct: 61 WNPQRRARVMMRFIELVNQHMDELAELLSIEHGKTVPDAKGDIQRGIEVIEFAIGIPHLI 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAGTGIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP Sbjct: 121 KGEYTEGAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP +QAVGFVGSSDIAQYIY+ A A Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILEHPVIQAVGFVGSSDIAQYIYAGATA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 +GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG+ETA+RLR Sbjct: 241 NGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGKETADRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 RL ERV LRVGHSLDPKADYGPLVTEAALNRV+DYI QGVEAGAE VVDGRER++DE+ Sbjct: 301 NRLVERVNNLRVGHSLDPKADYGPLVTEAALNRVRDYINQGVEAGAEAVVDGRERSSDEM 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 F D SLEGGYFIGPTLFDHV DMSIYTDEIFGPVLCIVRA +YEEAL LPT+HEYGNG Sbjct: 361 QFGDDSLEGGYFIGPTLFDHVTPDMSIYTDEIFGPVLCIVRADNYEEALRLPTEHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGD ARDFV++VQVGMVGVNVPIPVPV+YHTFGGWKRSGFGDLNQHGP SI FY Sbjct: 421 VAIFTRDGDTARDFVAKVQVGMVGVNVPIPVPVSYHTFGGWKRSGFGDLNQHGPHSILFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 TKTKTVT+RWPSGIKDGAEFVIPTMK Sbjct: 481 TKTKTVTQRWPSGIKDGAEFVIPTMK 506 >tr|A3PVH1|A3PVH1_MYCSJ Tax_Id=164757 SubName: Full=Methylmalonate-semialdehyde dehydrogenase [acylating; EC=1.2.1.27;[Mycobacterium sp.] Length = 506 Score = 859 bits (2219), Expect = 0.0 Identities = 424/506 (83%), Positives = 453/506 (89%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MT QIQHFING+RT+ STRTADVMNPSTG QKEWAA Sbjct: 1 MTNQIQHFINGKRTAGESTRTADVMNPSTGAVQAQVLLGSRADVDAAVAGAAEAQKEWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARV+M+FI+LVNQ+ DELA LLSIEHGKTV D+ GDIQRGIEVIEFA+GIPHL+ Sbjct: 61 WNPQRRARVMMRFIELVNQHMDELAELLSIEHGKTVPDAKGDIQRGIEVIEFAIGIPHLI 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAGTGIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP Sbjct: 121 KGEYTEGAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP +QAVGFVGSSDIAQYIY+ A A Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILEHPVIQAVGFVGSSDIAQYIYAGATA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 +GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG+ETA+RLR Sbjct: 241 NGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGKETADRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 RL ERV LRVGHSLDPKADYGPLVTEAALNRV+DYI QGVEAGAE VVDGRER++DE+ Sbjct: 301 NRLVERVNNLRVGHSLDPKADYGPLVTEAALNRVRDYINQGVEAGAEAVVDGRERSSDEM 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 F D SLEGGYFIGPTLFDHV DMSIYTDEIFGPVLCIVRA +YEEAL LPT+HEYGNG Sbjct: 361 QFGDDSLEGGYFIGPTLFDHVTPDMSIYTDEIFGPVLCIVRADNYEEALRLPTEHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGD ARDFV++VQVGMVGVNVPIPVPV+YHTFGGWKRSGFGDLNQHGP SI FY Sbjct: 421 VAIFTRDGDTARDFVAKVQVGMVGVNVPIPVPVSYHTFGGWKRSGFGDLNQHGPHSILFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 TKTKTVT+RWPSGIKDGAEFVIPTMK Sbjct: 481 TKTKTVTQRWPSGIKDGAEFVIPTMK 506 >tr|A1UBT6|A1UBT6_MYCSK Tax_Id=189918 SubName: Full=Methylmalonate-semialdehyde dehydrogenase (Acylating); EC=1.2.1.27;[Mycobacterium sp.] Length = 506 Score = 859 bits (2219), Expect = 0.0 Identities = 424/506 (83%), Positives = 453/506 (89%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MT QIQHFING+RT+ STRTADVMNPSTG QKEWAA Sbjct: 1 MTNQIQHFINGKRTAGESTRTADVMNPSTGAVQAQVLLGSRADVDAAVAGAAEAQKEWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARV+M+FI+LVNQ+ DELA LLSIEHGKTV D+ GDIQRGIEVIEFA+GIPHL+ Sbjct: 61 WNPQRRARVMMRFIELVNQHMDELAELLSIEHGKTVPDAKGDIQRGIEVIEFAIGIPHLI 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAGTGIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP Sbjct: 121 KGEYTEGAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP +QAVGFVGSSDIAQYIY+ A A Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILEHPVIQAVGFVGSSDIAQYIYAGATA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 +GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG+ETA+RLR Sbjct: 241 NGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGKETADRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 RL ERV LRVGHSLDPKADYGPLVTEAALNRV+DYI QGVEAGAE VVDGRER++DE+ Sbjct: 301 NRLVERVNNLRVGHSLDPKADYGPLVTEAALNRVRDYINQGVEAGAEAVVDGRERSSDEM 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 F D SLEGGYFIGPTLFDHV DMSIYTDEIFGPVLCIVRA +YEEAL LPT+HEYGNG Sbjct: 361 QFGDDSLEGGYFIGPTLFDHVTPDMSIYTDEIFGPVLCIVRADNYEEALRLPTEHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGD ARDFV++VQVGMVGVNVPIPVPV+YHTFGGWKRSGFGDLNQHGP SI FY Sbjct: 421 VAIFTRDGDTARDFVAKVQVGMVGVNVPIPVPVSYHTFGGWKRSGFGDLNQHGPHSILFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 TKTKTVT+RWPSGIKDGAEFVIPTMK Sbjct: 481 TKTKTVTQRWPSGIKDGAEFVIPTMK 506 >tr|B2HCW3|B2HCW3_MYCMM Tax_Id=216594 (mmsA)SubName: Full=Methylmalonate semialdehyde dehydrogenase, MmsA;[Mycobacterium marinum] Length = 506 Score = 854 bits (2207), Expect = 0.0 Identities = 420/506 (83%), Positives = 450/506 (88%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+GRRT STRTADV++P+TG Q WAA Sbjct: 1 MTTQIPHFIDGRRTPGQSTRTADVLDPNTGQVQATVPMAAQADIDAAVAGAAEAQIGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVNQN DELA LLS EHGKTV D+ GDIQRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNQNTDELAELLSREHGKTVPDARGDIQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVP+RLAELF+EAGLPPGVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIYS AAA Sbjct: 181 SVPLRLAELFVEAGLPPGVFQVVHGDKEAVDAILNHPEIKAVGFVGSSDIAQYIYSGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKRSQCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGE+TA+RLR Sbjct: 241 TGKRSQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEQTADRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 A+L ER+ LRVGHSLDPKADYGPLVTEAAL RV+DYIGQGV +GAELVVDGRERA+D+L Sbjct: 301 AKLVERINNLRVGHSLDPKADYGPLVTEAALTRVRDYIGQGVASGAELVVDGRERASDDL 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 F D +LEGGYFIGPTLFDHV TDMSIYTDEIFGPVLC+VRAHDYEEAL LP++HEYGNG Sbjct: 361 AFGDANLEGGYFIGPTLFDHVTTDMSIYTDEIFGPVLCMVRAHDYEEALRLPSEHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VA+FTRDGD ARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGP SIQFY Sbjct: 421 VAVFTRDGDTARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPTSIQFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 TK KTVT RWPSGIKDGAEFVIPTMK Sbjct: 481 TKVKTVTSRWPSGIKDGAEFVIPTMK 506 >tr|A0PMA6|A0PMA6_MYCUA Tax_Id=362242 (mmsA)SubName: Full=Methylmalonate semialdehyde dehydrogenase, MmsA;[Mycobacterium ulcerans] Length = 506 Score = 853 bits (2204), Expect = 0.0 Identities = 419/506 (82%), Positives = 449/506 (88%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+GRRT STRTADV++P+TG Q WAA Sbjct: 1 MTTQIPHFIDGRRTPGQSTRTADVLDPNTGQVQATVPMAAQADIDAAVAGAAEAQVGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVNQN DELA LLS EHGKTV D+ GDIQRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNQNTDELAELLSREHGKTVPDARGDIQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVP+RLAELF+EAGLPPGVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIYS AAA Sbjct: 181 SVPLRLAELFVEAGLPPGVFQVVHGDKEAVDAILNHPEIKAVGFVGSSDIAQYIYSGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKRSQCFGGAKNHMI+MPDADLDQAVDALIGAGYGS GERCMAISVAVPVGE+TA+RLR Sbjct: 241 TGKRSQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSTGERCMAISVAVPVGEQTADRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 A+L ER+ LRVGHSLDPKADYGPLVTEAAL RV+DYIGQGV +GAELVVDGRERA+D+L Sbjct: 301 AKLVERINNLRVGHSLDPKADYGPLVTEAALTRVRDYIGQGVASGAELVVDGRERASDDL 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 F D +LEGGYFIGPTLFDHV TDMSIYTDEIFGPVLC+VRAHDYEEAL LP++HEYGNG Sbjct: 361 AFGDANLEGGYFIGPTLFDHVTTDMSIYTDEIFGPVLCMVRAHDYEEALRLPSEHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VA+FTRDGD ARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGP SIQFY Sbjct: 421 VAVFTRDGDTARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPTSIQFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTMK 506 TK KTVT RWPSGIKDGAEFVIPTMK Sbjct: 481 TKVKTVTSRWPSGIKDGAEFVIPTMK 506 >tr|Q73S61|Q73S61_MYCPA Tax_Id=1770 (mmsA)SubName: Full=MmsA;[Mycobacterium paratuberculosis] Length = 506 Score = 841 bits (2172), Expect = 0.0 Identities = 416/505 (82%), Positives = 448/505 (88%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STRTADV +PSTG QK WAA Sbjct: 1 MTTQIPHFIDGQRTAGQSTRTADVFDPSTGAVQAQVPMAGRADIDAAVASAIEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 NPQRRARVLM+FI+LVNQ+ DELA LLS EHGKT+AD+ GDIQRGIEVIEF VGIPHLL Sbjct: 61 TNPQRRARVLMRFIELVNQHNDELAELLSREHGKTLADAKGDIQRGIEVIEFCVGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE++EGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYSEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELF+EAGLPPGVFQVV GDKEAVDAIL HP +QAVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFVEAGLPPGVFQVVHGDKEAVDAILNHPDIQAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKRSQCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA+RLR Sbjct: 241 TGKRSQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDKTADRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AA+ RV+DYI QGV AGAE+VVDGRER +D+L Sbjct: 301 ARLVERINNLRVGHSLDPKADYGPLVTGAAVARVRDYIDQGVAAGAEIVVDGRERRSDDL 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 TF D +LEGG+FIGPTLFDHV DMSIYTDEIFGPVLCIVRA +YEEAL LP++HEYGNG Sbjct: 361 TFGDANLEGGFFIGPTLFDHVTPDMSIYTDEIFGPVLCIVRAQNYEEALRLPSEHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VA+FTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY Sbjct: 421 VAVFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTM 505 TK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 TKVKTVTSRWPSGIKDGAEFVIPTM 505 >tr|A0QKW4|A0QKW4_MYCA1 Tax_Id=243243 (mmsA)SubName: Full=Methylmalonate-semialdehyde dehydrogenase; EC=1.2.1.27;[Mycobacterium avium] Length = 506 Score = 839 bits (2168), Expect = 0.0 Identities = 415/505 (82%), Positives = 448/505 (88%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STRTA+V +PSTG QK WAA Sbjct: 1 MTTQIPHFIDGQRTAGQSTRTAEVFDPSTGAVQAQVPMAGRADIDAAVASAIEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 NPQRRARVLM+FI+LVNQ+ DELA LLS EHGKT+AD+ GDIQRGIEVIEF VGIPHLL Sbjct: 61 TNPQRRARVLMRFIELVNQHNDELAELLSREHGKTLADAKGDIQRGIEVIEFCVGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE++EGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYSEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELF+EAGLPPGVFQVV GDKEAVDAIL HP +QAVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFVEAGLPPGVFQVVHGDKEAVDAILNHPDIQAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKRSQCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA+RLR Sbjct: 241 TGKRSQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDKTADRLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AA+ RV+DYI QGV AGAE+VVDGRER +D+L Sbjct: 301 ARLVERINNLRVGHSLDPKADYGPLVTGAAVARVRDYIDQGVAAGAEIVVDGRERRSDDL 360 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 TF D +LEGG+FIGPTLFDHV DMSIYTDEIFGPVLCIVRA +YEEAL LP++HEYGNG Sbjct: 361 TFGDANLEGGFFIGPTLFDHVTPDMSIYTDEIFGPVLCIVRAQNYEEALRLPSEHEYGNG 420 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VA+FTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY Sbjct: 421 VAVFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTM 505 TK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 TKVKTVTSRWPSGIKDGAEFVIPTM 505 >tr|A0QFM5|A0QFM5_MYCA1 Tax_Id=243243 (mmsA)SubName: Full=Methylmalonate-semialdehyde dehydrogenase; EC=1.2.1.27;[Mycobacterium avium] Length = 509 Score = 836 bits (2159), Expect = 0.0 Identities = 411/504 (81%), Positives = 448/504 (88%) Query: 2 TTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAY 61 TT I HFI+GRR++ S R+ADV +PSTG QK WAA Sbjct: 5 TTLIPHFIDGRRSAGQSGRSADVFDPSTGGVQATVPMAGQADIDAAVASAVEAQKGWAAT 64 Query: 62 NPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLK 121 NPQRRARV+M+F++LVN++ DELA LLS EHGKT+AD+ GDIQRGIEVIEF VGIPHLLK Sbjct: 65 NPQRRARVMMRFVELVNEHNDELAELLSREHGKTLADAKGDIQRGIEVIEFCVGIPHLLK 124 Query: 122 GEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPS 181 GE++EGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDPS Sbjct: 125 GEYSEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDPS 184 Query: 182 VPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAH 241 VPVRLAELF+EAGLPPGVFQVV GDKEAVDAIL HP +QAVGFVGSSDIAQYIY+ AAA Sbjct: 185 VPVRLAELFVEAGLPPGVFQVVHGDKEAVDAILNHPDIQAVGFVGSSDIAQYIYAGAAAT 244 Query: 242 GKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRA 301 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA+RLRA Sbjct: 245 GKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTADRLRA 304 Query: 302 RLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELT 361 RL ERV LRVGHSLDPKADYGPLVTEAAL RV+DYI QGV+AGAELV+DGRERA+D+L Sbjct: 305 RLIERVNNLRVGHSLDPKADYGPLVTEAALARVRDYIAQGVDAGAELVIDGRERASDDLA 364 Query: 362 FDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGV 421 F D +LEGG+FIGPTLFDHV DMSIYTDEIFGPVLCIVRAHDYEEAL+LP++HEYGNGV Sbjct: 365 FGDANLEGGFFIGPTLFDHVTPDMSIYTDEIFGPVLCIVRAHDYEEALALPSQHEYGNGV 424 Query: 422 AIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYT 481 A+FT DGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASI FYT Sbjct: 425 AVFTGDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASITFYT 484 Query: 482 KTKTVTERWPSGIKDGAEFVIPTM 505 KTKTVT+RWPSGIKDGAEF IPTM Sbjct: 485 KTKTVTQRWPSGIKDGAEFSIPTM 508 >tr|A2VG55|A2VG55_MYCTU Tax_Id=348776 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis C] Length = 510 Score = 830 bits (2144), Expect = 0.0 Identities = 413/509 (81%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGRERA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRERASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|O53816|O53816_MYCTU Tax_Id=1773 (mmsA)SubName: Full=PROBABLE METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE MMSA (METHYLMALONIC ACID SEMIALDEHYDE DEHYDROGENASE) (MMSDH); EC=1.2.1.27;[Mycobacterium tuberculosis] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|C6DUS0|C6DUS0_MYCTK Tax_Id=478434 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|C1AL88|C1AL88_MYCBT Tax_Id=561275 (mmsA)SubName: Full=Putative methylmalonate-semialdehyde dehydrogenase; EC=1.2.1.27;[Mycobacterium bovis] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|A5WKC1|A5WKC1_MYCTF Tax_Id=336982 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|A5U0E0|A5U0E0_MYCTA Tax_Id=419947 (mmsA)SubName: Full=Putative methylmalonate-semialdehyde dehydrogenase;[Mycobacterium tuberculosis] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|A1KGN5|A1KGN5_MYCBP Tax_Id=410289 (mmsA)SubName: Full=Probable methylmalonate-semialdehyde dehydrogenase mmsA; EC=1.2.1.27;[Mycobacterium bovis] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D6G0J2|D6G0J2_MYCTU Tax_Id=478435 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis KZN 605] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D6FER8|D6FER8_MYCTU Tax_Id=611303 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis CPHL_A] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D6F223|D6F223_MYCTU Tax_Id=611302 SubName: Full=Methylmalonate-semialdehyde dehydrogenase (Acylating);[Mycobacterium tuberculosis T46] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D5ZDF6|D5ZDF6_MYCTU Tax_Id=537210 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis T17] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D5Z0Y6|D5Z0Y6_MYCTU Tax_Id=537209 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis GM 1503] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D5YP48|D5YP48_MYCTU Tax_Id=515616 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis 02_1987] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D5YBM7|D5YBM7_MYCTU Tax_Id=520140 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis EAS054] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D5Y182|D5Y182_MYCTU Tax_Id=520141 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis T85] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D5XR38|D5XR38_MYCTU Tax_Id=515617 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis T92] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|A4KF68|A4KF68_MYCTU Tax_Id=395095 SubName: Full=Methylmalonate-semialdehyde dehydrogenase mmsA;[Mycobacterium tuberculosis str. Haarlem] Length = 510 Score = 829 bits (2141), Expect = 0.0 Identities = 412/509 (80%), Positives = 446/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|Q7D9C1|Q7D9C1_MYCTU Tax_Id=1773 (mmsA)SubName: Full=Methylmalonic acid semialdehyde dehydrogenase; EC=1.2.1.27;[Mycobacterium tuberculosis] Length = 510 Score = 827 bits (2136), Expect = 0.0 Identities = 411/509 (80%), Positives = 445/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 M TQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MATQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|Q7U1C7|Q7U1C7_MYCBO Tax_Id=1765 (mmsA)SubName: Full=PROBABLE METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE MMSA (METHYLMALONIC ACID SEMIALDEHYDE DEHYDROGENASE) (MMSDH); EC=1.2.1.27;[Mycobacterium bovis] Length = 510 Score = 826 bits (2134), Expect = 0.0 Identities = 411/509 (80%), Positives = 445/509 (87%), Gaps = 4/509 (0%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MTTQI HFI+G+RT+ STR+ADV +P+TG QK WAA Sbjct: 1 MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQRRARVLM+FI+LVN DELA LLS EHGKT+AD+ GD+QRGIEVIEF +GIPHLL Sbjct: 61 WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDP Sbjct: 121 KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVPVRLAELFIEAGLP GVFQVV GDKEAVDAIL HP ++AVGFVGSSDIAQYIY+ AAA Sbjct: 181 SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 GKR+QCFGGAKNHMI+MPDADLDQAVDALIGAGYGSAGERCMAISVAVPVG++TA RLR Sbjct: 241 TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 ARL ER+ LRVGHSLDPKADYGPLVT AAL RV+DYIGQGV AGAELVVDGR+RA+D+L Sbjct: 301 ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL 360 Query: 361 TF----DDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHE 416 TF D +LEGG+FIGPTLFDHV MSIYTDEIFGPVLC+VRA DYEEAL LP++HE Sbjct: 361 TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE 420 Query: 417 YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAS 476 YGNGVAIFTRDGDAARDFVSR QVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPA+ Sbjct: 421 YGNGVAIFTRDGDAARDFVSRGQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA 480 Query: 477 IQFYTKTKTVTERWPSGIKDGAEFVIPTM 505 IQFYTK KTVT RWPSGIKDGAEFVIPTM Sbjct: 481 IQFYTKVKTVTSRWPSGIKDGAEFVIPTM 509 >tr|D5UUU4|D5UUU4_TSUPA Tax_Id=521096 SubName: Full=Methylmalonate-semialdehyde dehydrogenase;[Tsukamurella paurometabola DSM 20162] Length = 506 Score = 815 bits (2106), Expect = 0.0 Identities = 404/505 (80%), Positives = 440/505 (87%), Gaps = 1/505 (0%) Query: 2 TTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAY 61 T I HFI+GRR G+ RTA+V +PSTG QK WAAY Sbjct: 3 TRAIPHFIDGRRVE-GTGRTAEVFDPSTGAVQATVPLATTAEVDDVVARAKEAQKVWAAY 61 Query: 62 NPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLK 121 NPQRRARV MKFI+LV+QN DELA LLS EHGKT+AD+ GDIQRGIEVIEF++GIPHLLK Sbjct: 62 NPQRRARVFMKFIELVHQNMDELASLLSSEHGKTLADAAGDIQRGIEVIEFSIGIPHLLK 121 Query: 122 GEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPS 181 GE+TEGAGTGIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAF+LKPSERDPS Sbjct: 122 GEYTEGAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDPS 181 Query: 182 VPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAH 241 VPVRLAELFIEAGLP GVFQVV GDKE+VDA+L +P ++AVGFVGSSDIAQYIY TAA + Sbjct: 182 VPVRLAELFIEAGLPEGVFQVVHGDKESVDALLNNPDIKAVGFVGSSDIAQYIYETAAKN 241 Query: 242 GKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRA 301 GKRSQ FGGAKNHMI++PDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR Sbjct: 242 GKRSQAFGGAKNHMIVLPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRE 301 Query: 302 RLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELT 361 RL ERV+QLRVGHS DPKADYGPL+T AA+ R + YI QGV+AGA+LVVDGRERA+DELT Sbjct: 302 RLVERVQQLRVGHSHDPKADYGPLITPAAVERTRSYIQQGVDAGADLVVDGRERASDELT 361 Query: 362 FDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGV 421 F D L GG ++GPTLFDHV DMSIYTDEIFGPVLCIVRA DYEEA++LPT+HEYGNGV Sbjct: 362 FGDADLSGGNYLGPTLFDHVTKDMSIYTDEIFGPVLCIVRAKDYEEAIALPTEHEYGNGV 421 Query: 422 AIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYT 481 AIFTRDGDAARDFV+RV+VGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGP SI FYT Sbjct: 422 AIFTRDGDAARDFVARVEVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPHSILFYT 481 Query: 482 KTKTVTERWPSGIKDGAEFVIPTMK 506 KTKTVT RWPSGIKDGAEF IPTM+ Sbjct: 482 KTKTVTSRWPSGIKDGAEFSIPTMR 506 >tr|D0L3S5|D0L3S5_GORB4 Tax_Id=526226 SubName: Full=Methylmalonate-semialdehyde dehydrogenase;[Gordonia bronchialis] Length = 513 Score = 806 bits (2082), Expect = 0.0 Identities = 397/508 (78%), Positives = 438/508 (86%), Gaps = 4/508 (0%) Query: 2 TTQIQHFINGRRTSA----GSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKE 57 +T I H+++G+R SA G R ADV NPSTG Q+E Sbjct: 5 STTIPHYLDGKRVSADQLPGEHRYADVFNPSTGAVAAQVPLASTDQVAAAVETAKAAQRE 64 Query: 58 WAAYNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIP 117 WAA+NPQRRARV+M+F+DLVN+NADELA LS+EHGKT AD+ GDIQRG+EVIEFA+GIP Sbjct: 65 WAAWNPQRRARVMMRFVDLVNKNADELATQLSLEHGKTHADARGDIQRGLEVIEFAIGIP 124 Query: 118 HLLKGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSE 177 HL+KGEFTEGAG+GIDV+S+RQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSE Sbjct: 125 HLIKGEFTEGAGSGIDVHSVRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSE 184 Query: 178 RDPSVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYST 237 RDPSVPVRLAELF EAGLP GVFQVV GDKEAVDA+LTHP V+A+GFVGSSDIAQYIY T Sbjct: 185 RDPSVPVRLAELFTEAGLPDGVFQVVHGDKEAVDALLTHPDVKALGFVGSSDIAQYIYET 244 Query: 238 AAAHGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETAN 297 AAAHGKRSQCFGGAKNHMIIMPDA+LDQAVDALIGAGYGSAGERCMAISVAVPVGE+TA Sbjct: 245 AAAHGKRSQCFGGAKNHMIIMPDANLDQAVDALIGAGYGSAGERCMAISVAVPVGEQTAE 304 Query: 298 RLRARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERAT 357 RLRA+L ++V LRVGHSLDPKADYGPLVT AAL RV+ YI +G E GAELV+DGRER + Sbjct: 305 RLRAKLVDKVNALRVGHSLDPKADYGPLVTAAALERVRGYIAKGAEEGAELVIDGRERTS 364 Query: 358 DELTFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEY 417 DE TF D+ + G+FIGPTLFDHV M+ YTDEIFGPVL IVRAHDYEEAL+L + H+Y Sbjct: 365 DEQTFGDEDISNGFFIGPTLFDHVTKGMTSYTDEIFGPVLQIVRAHDYEEALALASDHQY 424 Query: 418 GNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASI 477 GNGVAIFT+DGDAARDF SRV VGMVGVNVPIPVPVAY+TFGGWKRSGFGDLNQHGPASI Sbjct: 425 GNGVAIFTQDGDAARDFTSRVDVGMVGVNVPIPVPVAYYTFGGWKRSGFGDLNQHGPASI 484 Query: 478 QFYTKTKTVTERWPSGIKDGAEFVIPTM 505 QFYTKTKT+T RWPSGIKDGAEFVIPTM Sbjct: 485 QFYTKTKTITSRWPSGIKDGAEFVIPTM 512 >tr|A4F9Q3|A4F9Q3_SACEN Tax_Id=405948 (mmsA2)SubName: Full=Methylmalonate-semialdehyde dehydrogenase (Acylating); EC=1.2.1.27;[Saccharopolyspora erythraea] Length = 499 Score = 722 bits (1863), Expect = 0.0 Identities = 355/505 (70%), Positives = 407/505 (80%), Gaps = 7/505 (1%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 MT ++ HFI G+R + S DV +P++G Q WAA Sbjct: 1 MTNELGHFIGGKRVAGTSGSFGDVFDPNSGKVQARVALAAKEEVEAAVADAAEAQPGWAA 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 NPQ+RARVLM+F+ LVN D LARLL+ EHGKTVAD+ GDIQRG+EV+EFA GIPHLL Sbjct: 61 QNPQKRARVLMRFLQLVNDEMDSLARLLASEHGKTVADAKGDIQRGLEVVEFATGIPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE++E AGTGIDVYS+RQPLGVVAGITPFNFPAMIPLWKA PA+ACGNAF+LKPSERDP Sbjct: 121 KGEYSENAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAAPAIACGNAFVLKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVP+RLAELFIEAGLP G+F VV GDK AVDA+LT P +QAVGFVGSS IA+YIYSTAAA Sbjct: 181 SVPLRLAELFIEAGLPAGIFNVVNGDKTAVDAVLTDPRIQAVGFVGSSPIAEYIYSTAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 HGKR+QCFGGAKNHMI+MPDADLDQAVDAL+GAGYGSAGERCMAISVAVPVGE TA+ L Sbjct: 241 HGKRAQCFGGAKNHMIVMPDADLDQAVDALVGAGYGSAGERCMAISVAVPVGEPTADALV 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 +L ERV++L++G S D AD+GPL+T+ A RV D +G GVE GAEL+VDGR+ Sbjct: 301 EKLVERVRKLKIGTSFDADADFGPLITKQAWQRVHDLVGVGVEEGAELLVDGRD------ 354 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 F + E G+F+G +LFD VK DM IY +EIFGPVL +VRA DYEEAL LPT++EYGNG Sbjct: 355 -FSLEGNEDGFFMGASLFDRVKPDMRIYREEIFGPVLSVVRAADYEEALRLPTENEYGNG 413 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGDAAR+F SRV GMVGVNVPIPVP+AYHTFGGWKRSGFGDLNQHGP SI+FY Sbjct: 414 VAIFTRDGDAAREFTSRVNTGMVGVNVPIPVPIAYHTFGGWKRSGFGDLNQHGPDSIRFY 473 Query: 481 TKTKTVTERWPSGIKDGAEFVIPTM 505 TKTKTVT RWPSG+K+GA F IPTM Sbjct: 474 TKTKTVTSRWPSGLKEGASFTIPTM 498 >tr|D5PVL2|D5PVL2_COREQ Tax_Id=525370 (mmsA2)SubName: Full=Methylmalonate-semialdehyde dehydrogenase; EC=1.2.1.27;[Rhodococcus equi ATCC 33707] Length = 501 Score = 716 bits (1848), Expect = 0.0 Identities = 353/503 (70%), Positives = 408/503 (81%), Gaps = 8/503 (1%) Query: 4 QIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNP 63 ++ HFI G+R S R ADV +P+TG QKEWA++NP Sbjct: 5 ELSHFIGGKRIPGTSGRFADVFDPNTGQVQARVPLADRSETEAAIANAADAQKEWASWNP 64 Query: 64 QRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGE 123 QRRARVLM+F+ L+ + D LARLLS EHGKT+ D+ GDIQRG+EV+EFA GIPHLLKGE Sbjct: 65 QRRARVLMRFLQLIQEEMDPLARLLSSEHGKTIPDAKGDIQRGLEVVEFATGIPHLLKGE 124 Query: 124 FTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVP 183 +TEGAG+GIDV+S+RQPLGVVAGITPFNFPAMIPLWKA PALACGNAF+LKPSERDPSVP Sbjct: 125 YTEGAGSGIDVFSMRQPLGVVAGITPFNFPAMIPLWKAAPALACGNAFVLKPSERDPSVP 184 Query: 184 VRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGK 243 +RLAELF+EAGLPPGVF VV GDK AVD +LT P ++AVGFVGS+ IAQYIY TAAAHGK Sbjct: 185 LRLAELFLEAGLPPGVFNVVNGDKGAVDTLLTDPRIKAVGFVGSTPIAQYIYETAAAHGK 244 Query: 244 RSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARL 303 R+QCFGGAKNH I+MPDADLDQ DAL+GAGYGSAGERCMAISVAVPVGEETA+ L A+L Sbjct: 245 RAQCFGGAKNHAIVMPDADLDQVADALVGAGYGSAGERCMAISVAVPVGEETADALVAKL 304 Query: 304 TERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFD 363 +ERV +LR+G S D AD+GP+V++ AL+RV Y+ GV+ GAELV+DGR F Sbjct: 305 SERVAKLRIGRSDDETADFGPVVSKDALDRVDGYVQIGVDEGAELVIDGR-------GFT 357 Query: 364 DQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAI 423 + E G+F G TLFD V +M IY +EIFGPVL +VRAHDYEEAL LPT+HEYGNGVAI Sbjct: 358 LEGHENGFFAGATLFDRVTPEMRIYKEEIFGPVLQVVRAHDYEEALRLPTEHEYGNGVAI 417 Query: 424 FTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKT 483 FTRDGD ARDF SRV+VGMVGVNVPIPVP+AYHTFGGWKRSGFGDLNQHGP SI+FYTKT Sbjct: 418 FTRDGDTARDFCSRVEVGMVGVNVPIPVPIAYHTFGGWKRSGFGDLNQHGPDSIRFYTKT 477 Query: 484 KTVTERWPSGIKDGAE-FVIPTM 505 KTVT+RWPSG K+ ++ FVIPTM Sbjct: 478 KTVTQRWPSGFKEHSDHFVIPTM 500 >tr|C1AW62|C1AW62_RHOOB Tax_Id=632772 (mmsA)SubName: Full=Methylmalonate-semialdehyde dehydrogenase; EC=1.2.1.27;[Rhodococcus opacus] Length = 500 Score = 702 bits (1811), Expect = 0.0 Identities = 351/506 (69%), Positives = 398/506 (78%), Gaps = 8/506 (1%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 M ++ HF+ G+R S + DV +P+TG Q+EWA Sbjct: 1 MVQELSHFVGGKRVPGASNKFGDVYDPNTGEVQARVPLADKAETEAIIANAVEAQREWAL 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQ+RARVLMKF+ LV D LARLLS EHGKT+ D+ GDIQRG+EVIEFA+G PHLL Sbjct: 61 FNPQKRARVLMKFLQLVQDEMDSLARLLSSEHGKTIPDAKGDIQRGLEVIEFALGAPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TE AGTGIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALA GNAFILKPSERDP Sbjct: 121 KGEYTESAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAGPALAAGNAFILKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVP+RLAELF+EAGLP GVF VV GDKE VD +LT V+AVGFVGS+ IAQYIY TAAA Sbjct: 181 SVPLRLAELFLEAGLPAGVFNVVNGDKEVVDVLLTDDRVKAVGFVGSTPIAQYIYETAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 HGKR+QCFGGAKNH I+MPDADLD+ DALIGAGYGSAGERCMAISVAVPVGEETA+ L Sbjct: 241 HGKRAQCFGGAKNHAIVMPDADLDEVADALIGAGYGSAGERCMAISVAVPVGEETADALV 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 A+LTERV +L++G S D AD+GPLV++ A+ RV +YI G++ GAE VVDGR Sbjct: 301 AKLTERVGKLKIGRSDDEGADFGPLVSKDAVERVNNYIQIGLDEGAEAVVDGR------- 353 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 F + E G+F G TLFD V TDM +Y +EIFGPVL + RA DYEEAL LPT+HEYGNG Sbjct: 354 GFTLEGHENGFFAGATLFDKVTTDMRVYKEEIFGPVLLVARAADYEEALRLPTEHEYGNG 413 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGD ARDF SRVQVGMVGVNVPIPVP+AYHTFGGWKRSGFGDLNQHGP S +FY Sbjct: 414 VAIFTRDGDTARDFCSRVQVGMVGVNVPIPVPIAYHTFGGWKRSGFGDLNQHGPDSFRFY 473 Query: 481 TKTKTVTERWPSGIKDGA-EFVIPTM 505 TKTKTVT+RWPSG K+ FVIPTM Sbjct: 474 TKTKTVTQRWPSGKKEETNHFVIPTM 499 >tr|Q0SGI1|Q0SGI1_RHOSR Tax_Id=101510 (mmsA2)SubName: Full=Methylmalonate-semialdehyde dehydrogenase (Acylating); EC=1.2.1.27;[Rhodococcus sp.] Length = 500 Score = 701 bits (1810), Expect = 0.0 Identities = 350/506 (69%), Positives = 397/506 (78%), Gaps = 8/506 (1%) Query: 1 MTTQIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAA 60 M ++ HF+ G+R S + DV +P+TG Q+EWA Sbjct: 1 MVQELSHFVGGKRVPGASNKFGDVYDPNTGEVQARVPLADKAETEAIIANAVDAQREWAL 60 Query: 61 YNPQRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLL 120 +NPQ+RARVLMKF+ LV + D LARLLS EHGKT+ D+ GDIQRG+EVIEFA+G PHLL Sbjct: 61 FNPQKRARVLMKFLQLVQEEMDSLARLLSSEHGKTIPDAKGDIQRGLEVIEFALGAPHLL 120 Query: 121 KGEFTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDP 180 KGE+TE AGTGIDVYS+RQPLGVVAGITPFNFPAMIPLWKAGPALA GNAFILKPSERDP Sbjct: 121 KGEYTESAGTGIDVYSMRQPLGVVAGITPFNFPAMIPLWKAGPALAAGNAFILKPSERDP 180 Query: 181 SVPVRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAA 240 SVP+RLAELF+EAGLP GVF VV GDKE VD +LT V+AVGFVGS+ IAQYIY TAAA Sbjct: 181 SVPLRLAELFLEAGLPAGVFNVVNGDKEVVDVLLTDDRVKAVGFVGSTPIAQYIYETAAA 240 Query: 241 HGKRSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLR 300 HGKR+QCFGGAKNH IIMPDADLD+ DALIGAGYGSAGERCMAISVAVPVGEETA+ L Sbjct: 241 HGKRAQCFGGAKNHAIIMPDADLDEVADALIGAGYGSAGERCMAISVAVPVGEETADALV 300 Query: 301 ARLTERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDEL 360 A+LTERV +L +G S D AD+GPLV++ AL RV +YI G++ GAE V+DGR Sbjct: 301 AKLTERVGKLTIGRSDDESADFGPLVSKDALERVNNYIQIGIDEGAEAVIDGR------- 353 Query: 361 TFDDQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNG 420 F + E G+F G TLFD V TDM +Y +EIFGPVL + RA DYEEAL LPT+HEYGNG Sbjct: 354 GFTLEGHENGFFAGATLFDKVTTDMRVYKEEIFGPVLLVARAADYEEALRLPTEHEYGNG 413 Query: 421 VAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFY 480 VAIFTRDGD ARDF +RV VGMVGVNVPIPVP+AYHTFGGWKRSGFGDLNQHGP S +FY Sbjct: 414 VAIFTRDGDTARDFTNRVNVGMVGVNVPIPVPIAYHTFGGWKRSGFGDLNQHGPDSFRFY 473 Query: 481 TKTKTVTERWPSGIKDGA-EFVIPTM 505 TKTKTVT+RWPSG K+ FVIPTM Sbjct: 474 TKTKTVTQRWPSGKKEETNHFVIPTM 499 >tr|D1CZJ7|D1CZJ7_9RHIZ Tax_Id=520449 SubName: Full=Methylmalonate-semialdehyde dehydrogenase;[Brucella sp. 83/13] Length = 498 Score = 700 bits (1806), Expect = 0.0 Identities = 345/502 (68%), Positives = 394/502 (78%), Gaps = 7/502 (1%) Query: 5 IQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNPQ 64 I HFI G+ + S RTAD+ P G Q WAA NPQ Sbjct: 4 IGHFIGGKHVAGKSGRTADIFQPLDGTVQGKVALATKEEVRAAVENAKAAQPAWAATNPQ 63 Query: 65 RRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGEF 124 RR RVL KFI+LV D LA LL+ EHGKT+AD+ GDIQRG+EV+E +G H+LKGEF Sbjct: 64 RRVRVLRKFIELVEAEYDSLAELLAREHGKTIADARGDIQRGLEVVEVCLGAAHMLKGEF 123 Query: 125 TEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVPV 184 T+ AGTGID YS+RQPLGVVAGITPFNFPAMIPLWKAGPA+ACGNAFILKPSERDP VP+ Sbjct: 124 TDNAGTGIDTYSMRQPLGVVAGITPFNFPAMIPLWKAGPAIACGNAFILKPSERDPGVPM 183 Query: 185 RLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGKR 244 RLAELF+EAGLP G+F VV GDKE+VDA+L P VQA+GFVGS+ IAQYIY A+GKR Sbjct: 184 RLAELFLEAGLPAGIFNVVNGDKESVDALLDDPDVQAIGFVGSTPIAQYIYGRGCANGKR 243 Query: 245 SQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARLT 304 QCFGGAKNH++IMPDAD+DQ VDALIGAGYGSAGERCMAISVAVPVGE+TANRL +L Sbjct: 244 VQCFGGAKNHLLIMPDADMDQTVDALIGAGYGSAGERCMAISVAVPVGEDTANRLMEKLV 303 Query: 305 ERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFDD 364 RV+ L++G S D ADYGPLVT+AAL+RV+ Y+ GVE GA+LVVDGR F Sbjct: 304 PRVESLKIGPSTDNSADYGPLVTKAALDRVRGYVDLGVEEGAKLVVDGR-------NFKM 356 Query: 365 QSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAIF 424 Q E G+++G LFDHV DM IY +EIFGPVL IVRA +YEEAL+LP+ HE+GNGVAIF Sbjct: 357 QGYENGFYMGGCLFDHVTPDMRIYKEEIFGPVLSIVRAKNYEEALALPSDHEFGNGVAIF 416 Query: 425 TRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKTK 484 TRDGDAARDF SRVQVGMVG+NVPIPVP+AY+TFGGWK SGFGDLNQHGP + +FYTKTK Sbjct: 417 TRDGDAARDFASRVQVGMVGINVPIPVPIAYYTFGGWKASGFGDLNQHGPDAFRFYTKTK 476 Query: 485 TVTERWPSGIKDGAEFVIPTMK 506 TVT RWPSG+KDGAEFVIPTMK Sbjct: 477 TVTSRWPSGVKDGAEFVIPTMK 498 >tr|A8IML5|A8IML5_AZOC5 Tax_Id=438753 SubName: Full=Methylmalonate-semialdehyde dehydrogenase;[Azorhizobium caulinodans] Length = 498 Score = 699 bits (1805), Expect = 0.0 Identities = 350/502 (69%), Positives = 393/502 (78%), Gaps = 7/502 (1%) Query: 4 QIQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNP 63 ++ HFI G+ S R ADV P TG Q WAA NP Sbjct: 3 EMGHFIGGKHVPGTSGRHADVWQPMTGEVVGRVALASAAEMRAAVENAKAAQPAWAATNP 62 Query: 64 QRRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGE 123 QRRARVLMKF++LV ++ D LA LL+ EHGKTV D+ GDIQRG+EVIEFAVGIPHLLKGE Sbjct: 63 QRRARVLMKFLELVQRDYDALADLLAREHGKTVPDAKGDIQRGLEVIEFAVGIPHLLKGE 122 Query: 124 FTEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVP 183 FT+GAG GIDVYS+RQPLGVVAGITPFNFPAMIP+WK GPA+ACGNAFILKPSERDP VP Sbjct: 123 FTDGAGPGIDVYSMRQPLGVVAGITPFNFPAMIPMWKFGPAIACGNAFILKPSERDPGVP 182 Query: 184 VRLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGK 243 ++LAEL +EAGLPPG+ VV GDKEAVDAIL P +QAVGFVGSS IAQYIY+ AA GK Sbjct: 183 LKLAELMLEAGLPPGILNVVNGDKEAVDAILDDPDIQAVGFVGSSSIAQYIYARGAATGK 242 Query: 244 RSQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARL 303 R Q FGGAKNHMIIMPDAD+DQAVDALIGAGYGSAGERCMAISVAVPVGE A +L +L Sbjct: 243 RIQGFGGAKNHMIIMPDADMDQAVDALIGAGYGSAGERCMAISVAVPVGEAAAEKLIEKL 302 Query: 304 TERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFD 363 RV+ L++G S D AD+GPLVT AL RVK Y+ GV GA+L+VDGR F Sbjct: 303 VPRVESLKIGPSTDVTADFGPLVTREALERVKSYVDIGVNEGAKLLVDGR-------GFK 355 Query: 364 DQSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAI 423 Q E G+++G LFDHV DM IY +EIFGPVL +VRA DY+EAL LPT+HEYGNGVAI Sbjct: 356 LQGYENGFYLGGCLFDHVTPDMRIYKEEIFGPVLSVVRAKDYKEALRLPTEHEYGNGVAI 415 Query: 424 FTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKT 483 FTRDGDAARDF S+V VGMVG+NVPIPVP+AYHTFGGWKRSGFGDLNQHGP ++FYTKT Sbjct: 416 FTRDGDAARDFASKVNVGMVGINVPIPVPIAYHTFGGWKRSGFGDLNQHGPDGVRFYTKT 475 Query: 484 KTVTERWPSGIKDGAEFVIPTM 505 KTVT RWPSG+KDGAEFVIPTM Sbjct: 476 KTVTSRWPSGVKDGAEFVIPTM 497 >tr|A4YSQ9|A4YSQ9_BRASO Tax_Id=114615 SubName: Full=Methylmalonate-semialdehyde dehydrogenase; EC=1.2.1.27;[Bradyrhizobium sp.] Length = 498 Score = 699 bits (1805), Expect = 0.0 Identities = 343/502 (68%), Positives = 395/502 (78%), Gaps = 7/502 (1%) Query: 5 IQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNPQ 64 I HFI G+ S RTADV P TG Q WAA NPQ Sbjct: 4 IGHFIGGKEVKGTSGRTADVFEPMTGDVQAKVALASRAELRAAVENAKAAQPAWAATNPQ 63 Query: 65 RRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGEF 124 RRARV+MKF++L ++ D+LA LL+ EHGKTV D+ GDIQRG+EV+EFA GIPHL+KGE+ Sbjct: 64 RRARVMMKFLELAQRDYDQLAELLAREHGKTVPDAKGDIQRGLEVVEFACGIPHLMKGEY 123 Query: 125 TEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVPV 184 TEGAG GID+YS+RQPLGVVAGITPFNFPAMIP+WK PA+ACGNAFILKPSERDP VP+ Sbjct: 124 TEGAGPGIDIYSMRQPLGVVAGITPFNFPAMIPMWKFAPAIACGNAFILKPSERDPGVPM 183 Query: 185 RLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGKR 244 +LAEL IEAGLPPG+ VV GDKEAVDAIL P + AVGFVGSS IAQYIY AAAHGKR Sbjct: 184 KLAELMIEAGLPPGILNVVNGDKEAVDAILEDPDIMAVGFVGSSPIAQYIYERAAAHGKR 243 Query: 245 SQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARLT 304 QCFGGAKNH I+MPDADLDQAVDALIGAGYGSAGERCMA+SVAVPVG+ TA+RL +L Sbjct: 244 CQCFGGAKNHAIVMPDADLDQAVDALIGAGYGSAGERCMAVSVAVPVGKTTADRLMEKLI 303 Query: 305 ERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFDD 364 RV+ L++G S+DP ADYGPLVT A+ RVK+Y+ GV+ GA L VDGR F Sbjct: 304 PRVESLKIGTSIDPSADYGPLVTREAVERVKNYVDIGVKEGATLAVDGR-------GFKM 356 Query: 365 QSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAIF 424 Q E G+++G LFD+V DM IY +EIFGPVL +VRA DY EAL+LP++H+YGNGVAIF Sbjct: 357 QGYENGFYMGGCLFDNVTKDMRIYKEEIFGPVLSVVRAKDYAEALALPSEHDYGNGVAIF 416 Query: 425 TRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKTK 484 TRDGDAARDF +RV VGMVG+NVPIPVP+AY+TFGGWK+SGFGDLNQHGP SI+FYTKTK Sbjct: 417 TRDGDAARDFAARVNVGMVGINVPIPVPIAYYTFGGWKKSGFGDLNQHGPDSIRFYTKTK 476 Query: 485 TVTERWPSGIKDGAEFVIPTMK 506 TVT RWPSG+K+GAEF IP MK Sbjct: 477 TVTSRWPSGVKEGAEFSIPLMK 498 >tr|B1LX55|B1LX55_METRJ Tax_Id=426355 SubName: Full=Methylmalonate-semialdehyde dehydrogenase;[Methylobacterium radiotolerans] Length = 498 Score = 698 bits (1802), Expect = 0.0 Identities = 346/502 (68%), Positives = 396/502 (78%), Gaps = 7/502 (1%) Query: 5 IQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNPQ 64 I H+I GR S R ADV +PSTG Q WAA NPQ Sbjct: 4 IGHYIGGRNVGGESGRFADVFHPSTGEVQAKVALASKAELRAAVENAKAAQPAWAATNPQ 63 Query: 65 RRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGEF 124 +RARV+M+F++L+ D LA LL+ EHGKTV D+ GDIQRG+EV+EFA GIPHLLKGE+ Sbjct: 64 KRARVMMRFLELIRAENDSLAELLASEHGKTVPDAKGDIQRGVEVVEFACGIPHLLKGEY 123 Query: 125 TEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVPV 184 TEGAG GIDVYS+RQPLGVVAGITPFNFPAMIPLWK PA+ACGNAFILKPSERDPSVP+ Sbjct: 124 TEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKCAPAIACGNAFILKPSERDPSVPI 183 Query: 185 RLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGKR 244 R+AE+F+EAGLPPG+ VV GDKEAVDAIL ++AVGFVGSS IA+YIY AA GKR Sbjct: 184 RIAEIFLEAGLPPGILNVVNGDKEAVDAILDDEDIKAVGFVGSSHIAEYIYVRAAETGKR 243 Query: 245 SQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARLT 304 +QCFGGAKNHMIIMPDAD+ QAVDALIGAGYGSAGERCMAISVAVPVGE+TA+RL +L Sbjct: 244 AQCFGGAKNHMIIMPDADMGQAVDALIGAGYGSAGERCMAISVAVPVGEQTADRLMEKLI 303 Query: 305 ERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFDD 364 RV+ L++G S D ADYGPLVT A+ RVK YI +GV GA+L VDGR F Sbjct: 304 PRVESLKIGPSHDGSADYGPLVTAEAVERVKSYIDKGVAEGAQLAVDGR-------GFKL 356 Query: 365 QSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAIF 424 Q E G+++G +LFD V DM+IY +EIFGPVL +VRA DYEEAL+LP+ H+YGNGVAIF Sbjct: 357 QGYENGFYMGGSLFDRVTPDMTIYKEEIFGPVLSVVRAKDYEEALALPSTHQYGNGVAIF 416 Query: 425 TRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKTK 484 T+DGDAARDF +RV VGMVGVNVPIPVP+AYHTFGGWKRSGFGDLNQHGP SI+FYTKTK Sbjct: 417 TQDGDAARDFTARVNVGMVGVNVPIPVPIAYHTFGGWKRSGFGDLNQHGPDSIRFYTKTK 476 Query: 485 TVTERWPSGIKDGAEFVIPTMK 506 TVT+RWPSGIK GAEF IPTM+ Sbjct: 477 TVTQRWPSGIKSGAEFSIPTMR 498 >tr|A9M869|A9M869_BRUC2 Tax_Id=483179 (mmsA)SubName: Full=Methylmalonate-semialdehyde dehydrogenase;[Brucella canis] Length = 498 Score = 698 bits (1801), Expect = 0.0 Identities = 345/502 (68%), Positives = 393/502 (78%), Gaps = 7/502 (1%) Query: 5 IQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNPQ 64 I HFI G+ + S RTAD+ P G Q WAA NPQ Sbjct: 4 IGHFIGGKHVAGKSGRTADIFQPLDGTVQGKVALATKEEVRAAVENAKAAQPAWAATNPQ 63 Query: 65 RRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGEF 124 RR RVL KFI+LV D LA LL+ EHGKT+AD+ GDIQRG+EV+E +G H+LKGEF Sbjct: 64 RRVRVLRKFIELVEAEYDSLAELLAREHGKTIADARGDIQRGLEVVEVCLGAAHMLKGEF 123 Query: 125 TEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVPV 184 T+ AGTGID YS+RQPLGVVAGITPFNFPAMIPLWKAGPA+ACGNAFILKPSERDP VP+ Sbjct: 124 TDNAGTGIDTYSMRQPLGVVAGITPFNFPAMIPLWKAGPAIACGNAFILKPSERDPGVPM 183 Query: 185 RLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGKR 244 RLAELF EAGLP G+F VV GDKE+VDA+L P VQA+GFVGS+ IAQYIY A+GKR Sbjct: 184 RLAELFQEAGLPAGIFNVVNGDKESVDALLDDPDVQAIGFVGSTPIAQYIYGRGCANGKR 243 Query: 245 SQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARLT 304 QCFGGAKNH++IMPDAD+DQ VDALIGAGYGSAGERCMAISVAVPVGE+TANRL +L Sbjct: 244 VQCFGGAKNHLLIMPDADMDQTVDALIGAGYGSAGERCMAISVAVPVGEDTANRLMEKLI 303 Query: 305 ERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFDD 364 RV+ L++G S D ADYGPLVT+AAL+RV+ Y+ GVE GA+LVVDGR F Sbjct: 304 PRVESLKIGPSTDDSADYGPLVTKAALDRVRGYVDLGVEEGAKLVVDGR-------NFKM 356 Query: 365 QSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAIF 424 Q E G+++G LFDHV DM IY +EIFGPVL IVRA +YEEAL+LP+ HE+GNGVAIF Sbjct: 357 QGYENGFYMGGCLFDHVTPDMRIYKEEIFGPVLSIVRAKNYEEALALPSDHEFGNGVAIF 416 Query: 425 TRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKTK 484 TRDGDAARDF SRVQVGMVG+NVPIPVP+AY+TFGGWK SGFGDLNQHGP + +FYTKTK Sbjct: 417 TRDGDAARDFASRVQVGMVGINVPIPVPIAYYTFGGWKASGFGDLNQHGPDAFRFYTKTK 476 Query: 485 TVTERWPSGIKDGAEFVIPTMK 506 TVT RWPSG+KDGAEFVIPTMK Sbjct: 477 TVTSRWPSGVKDGAEFVIPTMK 498 >tr|D0BJ29|D0BJ29_BRUSU Tax_Id=520488 SubName: Full=ATP/GTP-binding site-containing protein A;[Brucella suis bv. 4 str. 40] Length = 498 Score = 698 bits (1801), Expect = 0.0 Identities = 345/502 (68%), Positives = 393/502 (78%), Gaps = 7/502 (1%) Query: 5 IQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNPQ 64 I HFI G+ + S RTAD+ P G Q WAA NPQ Sbjct: 4 IGHFIGGKHVAGKSGRTADIFQPLDGTVQGKVALATKEEVRAAVENAKAAQPAWAATNPQ 63 Query: 65 RRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGEF 124 RR RVL KFI+LV D LA LL+ EHGKT+AD+ GDIQRG+EV+E +G H+LKGEF Sbjct: 64 RRVRVLRKFIELVEAEYDSLAELLAREHGKTIADARGDIQRGLEVVEVCLGAAHMLKGEF 123 Query: 125 TEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVPV 184 T+ AGTGID YS+RQPLGVVAGITPFNFPAMIPLWKAGPA+ACGNAFILKPSERDP VP+ Sbjct: 124 TDNAGTGIDTYSMRQPLGVVAGITPFNFPAMIPLWKAGPAIACGNAFILKPSERDPGVPM 183 Query: 185 RLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGKR 244 RLAELF EAGLP G+F VV GDKE+VDA+L P VQA+GFVGS+ IAQYIY A+GKR Sbjct: 184 RLAELFQEAGLPAGIFNVVNGDKESVDALLDDPDVQAIGFVGSTPIAQYIYGRGCANGKR 243 Query: 245 SQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARLT 304 QCFGGAKNH++IMPDAD+DQ VDALIGAGYGSAGERCMAISVAVPVGE+TANRL +L Sbjct: 244 VQCFGGAKNHLLIMPDADMDQTVDALIGAGYGSAGERCMAISVAVPVGEDTANRLMEKLI 303 Query: 305 ERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFDD 364 RV+ L++G S D ADYGPLVT+AAL+RV+ Y+ GVE GA+LVVDGR F Sbjct: 304 PRVESLKIGPSTDDSADYGPLVTKAALDRVRGYVDLGVEEGAKLVVDGR-------NFKM 356 Query: 365 QSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAIF 424 Q E G+++G LFDHV DM IY +EIFGPVL IVRA +YEEAL+LP+ HE+GNGVAIF Sbjct: 357 QGYENGFYMGGCLFDHVTPDMRIYKEEIFGPVLSIVRAKNYEEALALPSDHEFGNGVAIF 416 Query: 425 TRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKTK 484 TRDGDAARDF SRVQVGMVG+NVPIPVP+AY+TFGGWK SGFGDLNQHGP + +FYTKTK Sbjct: 417 TRDGDAARDFASRVQVGMVGINVPIPVPIAYYTFGGWKASGFGDLNQHGPDAFRFYTKTK 476 Query: 485 TVTERWPSGIKDGAEFVIPTMK 506 TVT RWPSG+KDGAEFVIPTMK Sbjct: 477 TVTSRWPSGVKDGAEFVIPTMK 498 >tr|Q8FYN3|Q8FYN3_BRUSU Tax_Id=29461 (mmsA)SubName: Full=Methylmalonic acid semialdehyde dehydrogenase; EC=1.2.1.27;[Brucella suis] Length = 498 Score = 697 bits (1800), Expect = 0.0 Identities = 345/502 (68%), Positives = 393/502 (78%), Gaps = 7/502 (1%) Query: 5 IQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNPQ 64 I HFI G+ + S RTAD+ P G Q WAA NPQ Sbjct: 4 IGHFIGGKHVAGKSGRTADIFQPLDGTVQGKVALATKEEVRAAVENAKAAQPAWAATNPQ 63 Query: 65 RRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGEF 124 RR RVL KFI+LV D LA LL+ EHGKT+AD+ GDIQRG+EV+E +G H+LKGEF Sbjct: 64 RRVRVLRKFIELVEAEYDSLAELLAREHGKTIADARGDIQRGLEVVEVCLGAAHMLKGEF 123 Query: 125 TEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVPV 184 T+ AGTGID YS+RQPLGVVAGITPFNFPAMIPLWKAGPA+ACGNAFILKPSERDP VP+ Sbjct: 124 TDNAGTGIDTYSMRQPLGVVAGITPFNFPAMIPLWKAGPAIACGNAFILKPSERDPGVPM 183 Query: 185 RLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGKR 244 RLAELF EAGLP G+F VV GDKE+VDA+L P VQA+GFVGS+ IAQYIY A+GKR Sbjct: 184 RLAELFQEAGLPAGIFNVVNGDKESVDALLDDPDVQAIGFVGSTPIAQYIYGRGCANGKR 243 Query: 245 SQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARLT 304 QCFGGAKNH++IMPDAD+DQ VDALIGAGYGSAGERCMAISVAVPVGE+TANRL +L Sbjct: 244 VQCFGGAKNHLLIMPDADMDQTVDALIGAGYGSAGERCMAISVAVPVGEDTANRLMEKLI 303 Query: 305 ERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFDD 364 RV+ L++G S D ADYGPLVT+AAL+RV+ Y+ GVE GA+LVVDGR F Sbjct: 304 PRVESLKIGPSTDNSADYGPLVTKAALDRVRGYVDLGVEEGAKLVVDGR-------NFKM 356 Query: 365 QSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAIF 424 Q E G+++G LFDHV DM IY +EIFGPVL IVRA +YEEAL+LP+ HE+GNGVAIF Sbjct: 357 QGYENGFYMGGCLFDHVTPDMRIYKEEIFGPVLSIVRAKNYEEALALPSDHEFGNGVAIF 416 Query: 425 TRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKTK 484 TRDGDAARDF SRVQVGMVG+NVPIPVP+AY+TFGGWK SGFGDLNQHGP + +FYTKTK Sbjct: 417 TRDGDAARDFASRVQVGMVGINVPIPVPIAYYTFGGWKASGFGDLNQHGPDAFRFYTKTK 476 Query: 485 TVTERWPSGIKDGAEFVIPTMK 506 TVT RWPSG+KDGAEFVIPTMK Sbjct: 477 TVTSRWPSGVKDGAEFVIPTMK 498 >tr|C0G8L3|C0G8L3_9RHIZ Tax_Id=595497 (mmsA)SubName: Full=Methylmalonate-semialdehyde dehydrogenase; EC=2.6.1.33;[Brucella ceti str. Cudo] Length = 498 Score = 697 bits (1800), Expect = 0.0 Identities = 345/502 (68%), Positives = 393/502 (78%), Gaps = 7/502 (1%) Query: 5 IQHFINGRRTSAGSTRTADVMNPSTGXXXXXXXXXXXXXXXXXXXXXXXXQKEWAAYNPQ 64 I HFI G+ + S RTAD+ P G Q WAA NPQ Sbjct: 4 IGHFIGGKHVAGKSGRTADIFQPLDGTVQGKVALATKEEVRAAVENAKAAQPAWAATNPQ 63 Query: 65 RRARVLMKFIDLVNQNADELARLLSIEHGKTVADSLGDIQRGIEVIEFAVGIPHLLKGEF 124 RR RVL KFI+LV D LA LL+ EHGKT+AD+ GDIQRG+EV+E +G H+LKGEF Sbjct: 64 RRVRVLRKFIELVEAEYDSLAELLAREHGKTIADARGDIQRGLEVVEVCLGAAHMLKGEF 123 Query: 125 TEGAGTGIDVYSIRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFILKPSERDPSVPV 184 T+ AGTGID YS+RQPLGVVAGITPFNFPAMIPLWKAGPA+ACGNAFILKPSERDP VP+ Sbjct: 124 TDNAGTGIDTYSMRQPLGVVAGITPFNFPAMIPLWKAGPAIACGNAFILKPSERDPGVPM 183 Query: 185 RLAELFIEAGLPPGVFQVVQGDKEAVDAILTHPTVQAVGFVGSSDIAQYIYSTAAAHGKR 244 RLAELF EAGLP G+F VV GDKE+VDA+L P VQA+GFVGS+ IAQYIY A+GKR Sbjct: 184 RLAELFQEAGLPAGIFNVVNGDKESVDALLDDPDVQAIGFVGSTPIAQYIYGRGCANGKR 243 Query: 245 SQCFGGAKNHMIIMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEETANRLRARLT 304 QCFGGAKNH++IMPDAD+DQ VDALIGAGYGSAGERCMAISVAVPVGE+TANRL +L Sbjct: 244 VQCFGGAKNHLLIMPDADMDQTVDALIGAGYGSAGERCMAISVAVPVGEDTANRLMEKLI 303 Query: 305 ERVKQLRVGHSLDPKADYGPLVTEAALNRVKDYIGQGVEAGAELVVDGRERATDELTFDD 364 RV+ L++G S D ADYGPLVT+AAL+RV+ Y+ GVE GA+LVVDGR F Sbjct: 304 PRVESLKIGPSTDNSADYGPLVTKAALDRVRGYVDLGVEEGAKLVVDGR-------NFKM 356 Query: 365 QSLEGGYFIGPTLFDHVKTDMSIYTDEIFGPVLCIVRAHDYEEALSLPTKHEYGNGVAIF 424 Q E G+++G LFDHV DM IY +EIFGPVL IVRA +YEEAL+LP+ HE+GNGVAIF Sbjct: 357 QGYENGFYMGGCLFDHVTPDMRIYKEEIFGPVLSIVRAKNYEEALALPSDHEFGNGVAIF 416 Query: 425 TRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPASIQFYTKTK 484 TRDGDAARDF SRVQVGMVG+NVPIPVP+AY+TFGGWK SGFGDLNQHGP + +FYTKTK Sbjct: 417 TRDGDAARDFASRVQVGMVGINVPIPVPIAYYTFGGWKASGFGDLNQHGPDAFRFYTKTK 476 Query: 485 TVTERWPSGIKDGAEFVIPTMK 506 TVT RWPSG+KDGAEFVIPTMK Sbjct: 477 TVTSRWPSGVKDGAEFVIPTMK 498 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.319 0.137 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 4,122,625,830 Number of extensions: 179274337 Number of successful extensions: 480254 Number of sequences better than 10.0: 19341 Number of HSP's gapped: 420941 Number of HSP's successfully gapped: 19654 Length of query: 506 Length of database: 4,236,830,644 Length adjustment: 143 Effective length of query: 363 Effective length of database: 2,448,206,092 Effective search space: 888698811396 Effective search space used: 888698811396 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 83 (36.6 bits)