BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_1822
         (270 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|A0QTF5|A0QTF5_MYCS2 Tax_Id=246196 SubName: Full=Biotin-[acety...   468   e-130
tr|Q1BCG8|Q1BCG8_MYCSS Tax_Id=164756 SubName: Full=Biotin--acety...   260   1e-67
tr|A1UCH5|A1UCH5_MYCSK Tax_Id=189918 SubName: Full=Biotin--acety...   260   1e-67
tr|A4TF64|A4TF64_MYCGI Tax_Id=350054 SubName: Full=Biotin--acety...   259   2e-67
tr|A3PW65|A3PW65_MYCSJ Tax_Id=164757 SubName: Full=Biotin--acety...   259   3e-67
tr|A1T5U5|A1T5U5_MYCVP Tax_Id=350058 SubName: Full=Biotin--acety...   248   6e-64
tr|B1MF94|B1MF94_MYCA9 Tax_Id=561007 SubName: Full=Possible biot...   239   3e-61
tr|Q73UH1|Q73UH1_MYCPA Tax_Id=1770 (birA)SubName: Full=BirA;[Myc...   238   4e-61
tr|D5PCY8|D5PCY8_9MYCO Tax_Id=525368 (birA)SubName: Full=Biotin-...   236   2e-60
tr|A0QKF1|A0QKF1_MYCA1 Tax_Id=243243 SubName: Full=Biotin-[acety...   236   2e-60
tr|D6FRI1|D6FRI1_MYCTU Tax_Id=611304 SubName: Full=Biotin-[acety...   225   5e-57
tr|D5PQP9|D5PQP9_COREQ Tax_Id=525370 SubName: Full=Biotin-[acety...   224   1e-56
tr|Q0S316|Q0S316_RHOSR Tax_Id=101510 SubName: Full=Biotin--[acet...   223   1e-56
tr|Q7TWU0|Q7TWU0_MYCBO Tax_Id=1765 (birA)SubName: Full=POSSIBLE ...   223   2e-56
tr|P96884|P96884_MYCTU Tax_Id=1773 (birA)SubName: Full=BirA bifu...   223   2e-56
tr|C6DL16|C6DL16_MYCTK Tax_Id=478434 SubName: Full=Biotin-protei...   223   2e-56
tr|C1AH53|C1AH53_MYCBT Tax_Id=561275 (birA)SubName: Full=Putativ...   223   2e-56
tr|C0ZWV5|C0ZWV5_RHOE4 Tax_Id=234621 (birA)SubName: Full=Biotin ...   223   2e-56
tr|A5WSJ4|A5WSJ4_MYCTF Tax_Id=336982 SubName: Full=Bifunctional ...   223   2e-56
tr|A5U7V3|A5U7V3_MYCTA Tax_Id=419947 (birA)SubName: Full=Putativ...   223   2e-56
tr|A1KNT1|A1KNT1_MYCBP Tax_Id=410289 (birA)SubName: Full=Possibl...   223   2e-56
tr|D6G369|D6G369_MYCTU Tax_Id=478435 SubName: Full=Bifunctional ...   223   2e-56
tr|D6FLI6|D6FLI6_MYCTU Tax_Id=611303 SubName: Full=Biotin-[acety...   223   2e-56
tr|D5Z8C4|D5Z8C4_MYCTU Tax_Id=537209 SubName: Full=Biotin-(Acety...   223   2e-56
tr|D5YWN1|D5YWN1_MYCTU Tax_Id=515616 SubName: Full=Biotin operon...   223   2e-56
tr|D5Y8L2|D5Y8L2_MYCTU Tax_Id=520141 SubName: Full=Biotin operon...   223   2e-56
tr|A2VP75|A2VP75_MYCTU Tax_Id=348776 SubName: Full=Bifunctional ...   223   2e-56
tr|A4KLH5|A4KLH5_MYCTU Tax_Id=395095 SubName: Full=Bifunctional ...   223   2e-56
tr|C1B1A9|C1B1A9_RHOOB Tax_Id=632772 (birA)SubName: Full=Biotin ...   221   9e-56
tr|D6F9S9|D6F9S9_MYCTU Tax_Id=611302 SubName: Full=Biotin-[acety...   221   9e-56
tr|D5ZLF8|D5ZLF8_MYCTU Tax_Id=537210 SubName: Full=Bifunctional ...   221   9e-56
tr|D5YJP7|D5YJP7_MYCTU Tax_Id=520140 SubName: Full=Biotin operon...   221   9e-56
tr|D5XYV0|D5XYV0_MYCTU Tax_Id=515617 SubName: Full=Bifunctional ...   221   9e-56
tr|C3JG94|C3JG94_RHOER Tax_Id=596309 SubName: Full=Biotin-[acety...   221   9e-56
tr|Q9CCL3|Q9CCL3_MYCLE Tax_Id=1769 (birA)SubName: Full=Biotin ap...   219   4e-55
tr|B8ZUY1|B8ZUY1_MYCLB Tax_Id=561304 (birA)SubName: Full=Biotin ...   219   4e-55
tr|B2HEK8|B2HEK8_MYCMM Tax_Id=216594 (birA)SubName: Full=Bifunct...   216   2e-54
tr|A0PRJ0|A0PRJ0_MYCUA Tax_Id=362242 (birA)SubName: Full=Bifunct...   215   4e-54
tr|B5HUZ7|B5HUZ7_9ACTO Tax_Id=463191 SubName: Full=Biotin apo-pr...   206   2e-51
tr|D6KCF1|D6KCF1_9ACTO Tax_Id=645465 SubName: Full=Biotin-[acety...   201   6e-50
tr|Q5Z151|Q5Z151_NOCFA Tax_Id=37329 (birA)SubName: Full=Putative...   199   4e-49
tr|D3CG31|D3CG31_9ACTO Tax_Id=648999 SubName: Full=Biotin/acetyl...   196   2e-48
tr|D2PKN2|D2PKN2_KRIFD Tax_Id=479435 SubName: Full=Biotin/acetyl...   195   4e-48
tr|A6WEY2|A6WEY2_KINRD Tax_Id=266940 SubName: Full=Biotin--acety...   193   2e-47
tr|D6ECE7|D6ECE7_STRLI Tax_Id=457428 SubName: Full=Biotin-[acety...   192   3e-47

>tr|A0QTF5|A0QTF5_MYCS2 Tax_Id=246196 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase] ligase;
           EC=6.3.4.15;[Mycobacterium smegmatis]
          Length = 270

 Score =  468 bits (1205), Expect = e-130
 Identities = 245/270 (90%), Positives = 245/270 (90%)

Query: 1   MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE 60
           MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE
Sbjct: 1   MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE 60

Query: 61  HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEA 120
           HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEA
Sbjct: 61  HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEA 120

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
           KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLN            ATSLAMLTDAPV
Sbjct: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNVSVMPDDVPDSVATSLAMLTDAPV 180

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DRSALLTEFLTRLADRVESW             YRQCSGTLGTAVRVLLPGDRQLLGDAV
Sbjct: 181 DRSALLTEFLTRLADRVESWRAAGGADDRLLDDYRQCSGTLGTAVRVLLPGDRQLLGDAV 240

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLRPA 270
           DIDESGRLLIDSEGERITVAAGDVTHLRPA
Sbjct: 241 DIDESGRLLIDSEGERITVAAGDVTHLRPA 270


>tr|Q1BCG8|Q1BCG8_MYCSS Tax_Id=164756 SubName:
           Full=Biotin--acetyl-CoA-carboxylase
           ligase;[Mycobacterium sp.]
          Length = 270

 Score =  260 bits (664), Expect = 1e-67
 Identities = 143/269 (53%), Positives = 173/269 (64%), Gaps = 4/269 (1%)

Query: 1   MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE 60
           MN++  RP LD   +R+++      WR+ DVV ETGSTNADLLARA +G D+ G+VL  E
Sbjct: 1   MNTE-HRPPLDVTRLRASLGE---GWRTLDVVDETGSTNADLLARAAAGEDVAGSVLLTE 56

Query: 61  HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEA 120
            Q+AGRGR+GRQWT PPRSQ+A+SV +D  GV   AWG LPL TGVAV DA++ V+ VEA
Sbjct: 57  FQSAGRGRHGRQWTAPPRSQVAMSVAVDAGGVRPDAWGWLPLLTGVAVRDAVAEVSAVEA 116

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVLV  GKLAGILAEVA+P   V++G GLN            ATSL ML     
Sbjct: 117 GLKWPNDVLVGEGKLAGILAEVAAPQHVVIVGIGLNVTLSAAEAPDPRATSLTMLGARNH 176

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+AL    L  L  R+  W             YR+ S TLG  V   LPGDR+L G A 
Sbjct: 177 DRTALAAALLRNLGTRIARWRRAAGADEGLIADYRRHSLTLGREVTATLPGDRRLDGTAT 236

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLRP 269
           DID+ GRL I +  + +TVAAGD+THLRP
Sbjct: 237 DIDDLGRLTITTGRDSVTVAAGDITHLRP 265


>tr|A1UCH5|A1UCH5_MYCSK Tax_Id=189918 SubName:
           Full=Biotin--acetyl-CoA-carboxylase
           ligase;[Mycobacterium sp.]
          Length = 270

 Score =  260 bits (664), Expect = 1e-67
 Identities = 143/269 (53%), Positives = 173/269 (64%), Gaps = 4/269 (1%)

Query: 1   MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE 60
           MN++  RP LD   +R+++      WR+ DVV ETGSTNADLLARA +G D+ G+VL  E
Sbjct: 1   MNTE-HRPPLDVTRLRASLGE---GWRTLDVVDETGSTNADLLARAAAGEDVAGSVLLTE 56

Query: 61  HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEA 120
            Q+AGRGR+GRQWT PPRSQ+A+SV +D  GV   AWG LPL TGVAV DA++ V+ VEA
Sbjct: 57  FQSAGRGRHGRQWTAPPRSQVAMSVAVDAGGVRPDAWGWLPLLTGVAVRDAVAEVSAVEA 116

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVLV  GKLAGILAEVA+P   V++G GLN            ATSL ML     
Sbjct: 117 GLKWPNDVLVGEGKLAGILAEVAAPQHVVIVGIGLNVTLSAAEAPDPRATSLTMLGARNH 176

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+AL    L  L  R+  W             YR+ S TLG  V   LPGDR+L G A 
Sbjct: 177 DRTALAAALLRNLGTRIARWRRAAGADEGLIADYRRHSLTLGREVTATLPGDRRLDGTAT 236

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLRP 269
           DID+ GRL I +  + +TVAAGD+THLRP
Sbjct: 237 DIDDLGRLTITTGRDSVTVAAGDITHLRP 265


>tr|A4TF64|A4TF64_MYCGI Tax_Id=350054 SubName:
           Full=Biotin--acetyl-CoA-carboxylase
           ligase;[Mycobacterium gilvum]
          Length = 266

 Score =  259 bits (663), Expect = 2e-67
 Identities = 139/265 (52%), Positives = 171/265 (64%), Gaps = 5/265 (1%)

Query: 6   ERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQTAG 65
           ERPAL+ D +RSA+      W   DVV ETGSTNADL+ARA  G DI GAVL AEHQTAG
Sbjct: 5   ERPALNVDVLRSAITGTE--WHRVDVVDETGSTNADLIARADRGEDIAGAVLLAEHQTAG 62

Query: 66  RGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEAKLKWP 125
           RGR+GR W+ PPRSQI++S G+DTTGVP   WG LPL TG+AV   +    GV A +KWP
Sbjct: 63  RGRHGRTWSAPPRSQISMSFGVDTTGVPPAGWGWLPLLTGLAVAHTLRESYGVNAGVKWP 122

Query: 126 NDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPVDRSAL 185
           NDV+V   KLAGILAEV+   P +V+G GLN            A SL+ML +   DR+ L
Sbjct: 123 NDVMVGPRKLAGILAEVS--GPVIVVGLGLNVEMTVDELPDPNAMSLSML-NHHADRTQL 179

Query: 186 LTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAVDIDES 245
               L   + R+  W             YR+ S T+GT VR LLPGD +++G A  ID++
Sbjct: 180 TASLLQEFSSRLRRWRLAGGADAGLATDYRERSTTIGTRVRALLPGDSEIIGVATGIDDA 239

Query: 246 GRLLIDSEGERITVAAGDVTHLRPA 270
           GRLLID+EG  +TV+A D+THLRPA
Sbjct: 240 GRLLIDTEGTTVTVSAADITHLRPA 264


>tr|A3PW65|A3PW65_MYCSJ Tax_Id=164757 SubName:
           Full=Biotin--acetyl-CoA-carboxylase
           ligase;[Mycobacterium sp.]
          Length = 270

 Score =  259 bits (661), Expect = 3e-67
 Identities = 142/269 (52%), Positives = 173/269 (64%), Gaps = 4/269 (1%)

Query: 1   MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE 60
           MN++  RP LD   +R+++      WR+ DVV ETGSTNADLLARA +G D+ G+VL  E
Sbjct: 1   MNTE-HRPPLDVTRLRASLGE---GWRTLDVVDETGSTNADLLARAAAGEDVAGSVLLTE 56

Query: 61  HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEA 120
            Q++GRGR+GRQWT PPRSQ+A+SV +D  GV   AWG LPL TGVAV DA++ V+ VEA
Sbjct: 57  FQSSGRGRHGRQWTAPPRSQVAMSVAVDAGGVRPDAWGWLPLLTGVAVRDAVAEVSAVEA 116

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVLV  GKLAGILAEVA+P   V++G GLN            ATSL ML     
Sbjct: 117 GLKWPNDVLVGEGKLAGILAEVAAPQHVVIVGIGLNVTLSAAEAPDPRATSLTMLGARNH 176

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+AL    L  L  R+  W             YR+ S TLG  V   LPGDR+L G A 
Sbjct: 177 DRTALAAALLRNLGTRIARWRRAAGADEGLIADYRRHSLTLGREVTATLPGDRRLDGTAT 236

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLRP 269
           DID+ GRL I +  + +TVAAGD+THLRP
Sbjct: 237 DIDDLGRLTITTGRDSVTVAAGDITHLRP 265


>tr|A1T5U5|A1T5U5_MYCVP Tax_Id=350058 SubName:
           Full=Biotin--acetyl-CoA-carboxylase
           ligase;[Mycobacterium vanbaalenii]
          Length = 257

 Score =  248 bits (633), Expect = 6e-64
 Identities = 136/259 (52%), Positives = 169/259 (65%), Gaps = 8/259 (3%)

Query: 10  LDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQTAGRGRN 69
           L+ D +R+AV      WR  DVV ETGSTNADL+ARA +G DI GAVL AEHQTAGRGR+
Sbjct: 5   LNIDELRAAVSDTE--WRRVDVVEETGSTNADLIARAAAGEDIAGAVLLAEHQTAGRGRH 62

Query: 70  GRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEAKLKWPNDVL 129
           GR W+ PPRSQI++SVG+D TGVP+  WG LPL TG+AV   +    GV+A +KWPND+L
Sbjct: 63  GRSWSAPPRSQISMSVGVDATGVPAERWGWLPLLTGLAVAHVVREDYGVDAGVKWPNDIL 122

Query: 130 VDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPVDRSALLTEF 189
           V TGKLAGILAEV+  AP +V+G GLN            A SL ML     DR+AL    
Sbjct: 123 VGTGKLAGILAEVS--APVIVVGLGLNVSFTADELPDPNAVSLMML-GHDADRTALAATV 179

Query: 190 LTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAVDIDESGRLL 249
           L  L+ ++  W             YR  S TLG  VR +LPG  +++G A  ID++GRLL
Sbjct: 180 LQELSRQLHRW---RAGDPGLAADYRNASTTLGAPVRAVLPGGSEIVGVATGIDDAGRLL 236

Query: 250 IDSEGERITVAAGDVTHLR 268
           ID +G  +TV+AGD+THLR
Sbjct: 237 IDDDGTTVTVSAGDITHLR 255


>tr|B1MF94|B1MF94_MYCA9 Tax_Id=561007 SubName: Full=Possible
           biotin--acetyl-CoA-carboxylase ligase (BirA bifunctional
           protein);[Mycobacterium abscessus]
          Length = 264

 Score =  239 bits (610), Expect = 3e-61
 Identities = 127/249 (51%), Positives = 158/249 (63%), Gaps = 1/249 (0%)

Query: 22  PRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQTAGRGRNGRQWTTPPRSQI 81
           P G WR  DVV ETGSTNADL+ RA +G DI+G VL AEHQTAGRGR+GR W  P  +Q+
Sbjct: 12  PGGHWRRIDVVEETGSTNADLVTRAAAGEDIDGVVLLAEHQTAGRGRHGRSWGAPAHTQL 71

Query: 82  AVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEAKLKWPNDVLVDTGKLAGILAE 141
           ++SVGI    VP   WGL+PL  GVA+VDA++ V+G++A LKWPNDVLVD  KL GILAE
Sbjct: 72  SMSVGIGVGEVPPDRWGLVPLLAGVAIVDAVAEVSGIQAGLKWPNDVLVDGRKLCGILAE 131

Query: 142 VASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPVDRSALLTEFLTRLADRVESWX 201
           VA+P   +V+G GLN            ATSL +L  A  DR  L    L  L  R+E W 
Sbjct: 132 VATPHQAIVLGLGLNATFAQHELPDPNATSLTILGWADPDRDELARAVLRELGGRIEHWR 191

Query: 202 XXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAVDIDESGRLLID-SEGERITVA 260
                       YR+ S TLG+ VR  LPG+R+L+G AV +   G+L I+ ++G    V 
Sbjct: 192 AARGLDERLLEDYRERSVTLGSRVRAELPGERELVGVAVGLGNDGQLRIEAADGTVTAVT 251

Query: 261 AGDVTHLRP 269
           AGD+THLRP
Sbjct: 252 AGDITHLRP 260


>tr|Q73UH1|Q73UH1_MYCPA Tax_Id=1770 (birA)SubName:
           Full=BirA;[Mycobacterium paratuberculosis]
          Length = 281

 Score =  238 bits (608), Expect = 4e-61
 Identities = 137/272 (50%), Positives = 166/272 (61%), Gaps = 9/272 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  R  LDA A+R+ ++     WR  DVV +TGSTNADLLARA +G D+ GAVL AEHQT
Sbjct: 12  DRLRAPLDAAALRAELIGTGLGWRRLDVVEQTGSTNADLLARAAAGDDVAGAVLIAEHQT 71

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAV---TGVEA 120
           AGRGR+GR W+  PR+Q+ +SVG+    VP+  WG LPLATGVAVVD ++ +    GV  
Sbjct: 72  AGRGRHGRGWSATPRAQVTMSVGVSVVDVPAAGWGWLPLATGVAVVDTVAPLLQPAGVAV 131

Query: 121 KLKWPNDVLV----DTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLT 176
            LKWPNDVL       GKLAGILAEV+   P VVIG GLN            ATSL  L 
Sbjct: 132 GLKWPNDVLAGPAGTPGKLAGILAEVSK--PVVVIGLGLNVTQSADEIDGPGATSLLDLG 189

Query: 177 DAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLL 236
            A  DR+AL++  L  L  R+ SW             YR  S T+GT VR  LPG + + 
Sbjct: 190 VAAPDRTALVSGLLRELGRRIVSWQAARGADWALAADYRARSLTIGTRVRADLPGGKHVE 249

Query: 237 GDAVDIDESGRLLIDSEGERITVAAGDVTHLR 268
           G A  ID+ GRL +DS G+ + VAAGDV HLR
Sbjct: 250 GTASGIDDQGRLCLDSGGQTVVVAAGDVVHLR 281


>tr|D5PCY8|D5PCY8_9MYCO Tax_Id=525368 (birA)SubName:
           Full=Biotin--[acetyl-CoA-carboxylase] ligase;
           EC=6.3.4.15;[Mycobacterium parascrofulaceum ATCC
           BAA-614]
          Length = 260

 Score =  236 bits (603), Expect = 2e-60
 Identities = 137/264 (51%), Positives = 166/264 (62%), Gaps = 9/264 (3%)

Query: 10  LDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQTAGRGRN 69
           +D  A+R+ ++     WR  DVV ETGSTNADLLA+A SG D+ GAVL AEHQTAGRGR 
Sbjct: 1   MDQAALRAELIGTGLGWRRLDVVDETGSTNADLLAQAASGADLAGAVLIAEHQTAGRGRQ 60

Query: 70  GRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS-AVTGVEAKLKWPNDV 128
           GR W+  PR+QI +SVG+    VP+  WG LPLATGVAVVDA++  + GVE  LKWPNDV
Sbjct: 61  GRGWSATPRTQITMSVGVSVVDVPTAGWGWLPLATGVAVVDAVAPLLDGVEVGLKWPNDV 120

Query: 129 LV----DTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPVDRSA 184
           L       GKLAGILAEVA   P VVIG GLN            ATSLA L  A  DR+ 
Sbjct: 121 LAGPPGSPGKLAGILAEVA--RPVVVIGLGLN--VFEAPDGIEGATSLADLGLASPDRTR 176

Query: 185 LLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAVDIDE 244
           L++  LT L  R+ +W             YR  S TLG  VR  LPG R+++G A  +D+
Sbjct: 177 LVSGLLTELGRRIVAWRAARGADWALAADYRARSLTLGNRVRAHLPGGREVVGVATAVDD 236

Query: 245 SGRLLIDSEGERITVAAGDVTHLR 268
            GRL ID+ G+ + V+AGDV HLR
Sbjct: 237 QGRLCIDTGGQTVVVSAGDVVHLR 260


>tr|A0QKF1|A0QKF1_MYCA1 Tax_Id=243243 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase] ligase;
           EC=6.3.4.15;[Mycobacterium avium]
          Length = 264

 Score =  236 bits (602), Expect = 2e-60
 Identities = 134/266 (50%), Positives = 164/266 (61%), Gaps = 9/266 (3%)

Query: 10  LDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQTAGRGRN 69
           +DA A+R+ ++     WR  DVV +TGSTNADLLARA +G D+ GAVL AEHQTAGRGR+
Sbjct: 1   MDAAALRAELIGTGLGWRRLDVVEQTGSTNADLLARAAAGDDVAGAVLIAEHQTAGRGRH 60

Query: 70  GRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAV---TGVEAKLKWPN 126
           GR W+  PR+Q+ +SVG+    VP+  WG LPLATGVAVVD ++ +    GV   LKWPN
Sbjct: 61  GRGWSATPRAQVTMSVGVSVVDVPAAGWGWLPLATGVAVVDTVAPLLQPAGVAVGLKWPN 120

Query: 127 DVLV----DTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPVDR 182
           DVL       GKLAGILAEV+   P VVIG GLN            ATSL  L  A  DR
Sbjct: 121 DVLAGPAGSPGKLAGILAEVSK--PVVVIGLGLNVTQSADEIDGPGATSLLDLGVAAPDR 178

Query: 183 SALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAVDI 242
           +AL++  L  L  R+ SW             YR  S T+GT VR  LPG + + G A  I
Sbjct: 179 TALVSGLLRELGRRIVSWQAARGADWALAADYRARSLTIGTRVRADLPGGKHIEGTAGGI 238

Query: 243 DESGRLLIDSEGERITVAAGDVTHLR 268
           D+ GRL +DS G+ + VAAGDV HLR
Sbjct: 239 DDQGRLCLDSGGQTVVVAAGDVVHLR 264


>tr|D6FRI1|D6FRI1_MYCTU Tax_Id=611304 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase]
           ligase;[Mycobacterium tuberculosis K85]
          Length = 266

 Score =  225 bits (573), Expect = 5e-57
 Identities = 133/268 (49%), Positives = 162/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR FDVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQFDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAANYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDHGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D5PQP9|D5PQP9_COREQ Tax_Id=525370 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase] ligase;
           EC=6.3.4.15;[Rhodococcus equi ATCC 33707]
          Length = 277

 Score =  224 bits (570), Expect = 1e-56
 Identities = 131/277 (47%), Positives = 166/277 (59%), Gaps = 11/277 (3%)

Query: 1   MNSDTERPALDADAIRSAVVRPRGS-----WRSFDVVAETGSTNADLLARARSGTDINGA 55
           M +D  RP LDA  +R A+VR  G      W   DVV ETGSTNADLLA  R   D   +
Sbjct: 1   MWTDLNRPPLDAGVLRRALVRDAGGDPDAFWSRVDVVTETGSTNADLLAAPRDA-DYPRS 59

Query: 56  VLAAEHQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAV 115
           VL AEHQT GRGR+ R W + PR+ + VS  +D  G+     G LPL  GVAVVD +   
Sbjct: 60  VLIAEHQTGGRGRHARPWVSAPRALVTVSAVLDMPGMDLADIGWLPLLAGVAVVDVLRGT 119

Query: 116 TGVEAKLKWPNDVLVDTGKLAGILAEVA--SPAPTVVIGTGLNXXXXXXXXXXXXATSLA 173
            GV+A+LKWPNDVL+   K+ GILAEVA  +P PTVV+G GLN            ATSL 
Sbjct: 120 AGVDAELKWPNDVLIGGRKVVGILAEVAATAPVPTVVVGIGLNVSLTEDELPVPTATSL- 178

Query: 174 MLTDAPV-DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGD 232
           +L DA V DR+ L+   L  LA R   W             Y++  GTLG  VR  LPGD
Sbjct: 179 LLEDAEVTDRTVLVRAILRELARRHREWEAAGWKVGALAAAYKERCGTLGRRVRAELPGD 238

Query: 233 RQLLGDAVDIDESGRLLIDSEGER-ITVAAGDVTHLR 268
           R+L+G A+D+D  GR++I+++G+  + V+AGD+THLR
Sbjct: 239 RELIGTAIDVDVEGRIVIEADGKSPVAVSAGDITHLR 275


>tr|Q0S316|Q0S316_RHOSR Tax_Id=101510 SubName:
           Full=Biotin--[acetyl-CoA-carboxylase] ligase;
           EC=6.3.4.15;[Rhodococcus sp.]
          Length = 282

 Score =  223 bits (569), Expect = 1e-56
 Identities = 134/279 (48%), Positives = 169/279 (60%), Gaps = 11/279 (3%)

Query: 1   MNSDTERPALDADAIRSAVVR------PRGSWRSFDVVAETGSTNADLLARARSGTDING 54
           M +D  RP L+AD +R+A+VR       R  W   DVV ETGSTNADLLARA + ++ + 
Sbjct: 1   MWTDLNRPPLNADNLRAALVRGDDDSDTRRFWARLDVVQETGSTNADLLARAAT-SNCDR 59

Query: 55  AVLAAEHQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISA 114
            VL AE Q +GRGR+ R W +PP++QIAVSV +   G+     G LPL TGVAVVDA+ A
Sbjct: 60  HVLLAEFQGSGRGRHSRAWVSPPQAQIAVSVLLTMPGMSVQDMGWLPLLTGVAVVDALRA 119

Query: 115 VTGVEAKLKWPNDVLVDTGKLAGILAEVA--SPAPTVVIGTGLNXXXXXXXXXXXXATSL 172
            T V A+LKWPNDVL+D  K+AGILAEV+  +P P VV+G GLN            ATSL
Sbjct: 120 ATKVPAELKWPNDVLIDGRKVAGILAEVSATAPDPAVVVGIGLNVSLTRDELPVEHATSL 179

Query: 173 AMLTDAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGD 232
            +      DR  L+   L  +ADR + W             YR   GTLG  VR  LPG 
Sbjct: 180 VLEGAEVSDRDTLVRAVLRAIADRWQQWHDANWDVTELAEAYRARCGTLGQRVRAELPGG 239

Query: 233 RQLLGDAVDIDESGRLLIDSEGE--RITVAAGDVTHLRP 269
           R+L+G A D+D  GR++I  +G+   I VAAGD+THLRP
Sbjct: 240 RELIGIATDVDAEGRVVIAPDGQPGTIAVAAGDITHLRP 278


>tr|Q7TWU0|Q7TWU0_MYCBO Tax_Id=1765 (birA)SubName: Full=POSSIBLE
           BIFUNCTIONAL PROTEIN BIRA: BIOTIN OPERON REPRESSOR +
           BIOTIN--[ACETYL-COA-CARBOXYLASE] SYNTHETASE
           (BIOTIN--PROTEIN LIGASE); EC=6.3.4.15;[Mycobacterium
           bovis]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAANYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|P96884|P96884_MYCTU Tax_Id=1773 (birA)SubName: Full=BirA
           bifunctional protein; EC=6.3.4.15; SubName:
           Full=POSSIBLE BIFUNCTIONAL PROTEIN BIRA: BIOTIN OPERON
           REPRESSOR + BIOTIN--[ACETYL-COA-CARBOXYLASE] SYNTHETASE
           (BIOTIN--PROTEIN LIGASE); EC=6.3.4.15;[Mycobacterium
           tuberculosis]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|C6DL16|C6DL16_MYCTK Tax_Id=478434 SubName: Full=Biotin-protein
           ligase;[Mycobacterium tuberculosis]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|C1AH53|C1AH53_MYCBT Tax_Id=561275 (birA)SubName: Full=Putative
           biotin operon repressor; EC=6.3.4.15;[Mycobacterium
           bovis]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAANYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|C0ZWV5|C0ZWV5_RHOE4 Tax_Id=234621 (birA)SubName: Full=Biotin
           protein ligase; EC=6.3.4.15;[Rhodococcus erythropolis]
          Length = 284

 Score =  223 bits (568), Expect = 2e-56
 Identities = 131/280 (46%), Positives = 170/280 (60%), Gaps = 11/280 (3%)

Query: 1   MNSDTERPALDADAIRSAVVRP-----RGSWRSFDVVAETGSTNADLLARARSGTDINGA 55
           M +D  RP LD +A+R A+VR      R  W   DVV ETGSTNADLLARA +  D +  
Sbjct: 1   MWTDLNRPPLDGNALRRALVRSDNDDARVFWNRLDVVEETGSTNADLLARA-ADPDADRH 59

Query: 56  VLAAEHQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAV 115
           VL AE+Q + RGR+ R W +PP++QI++SV +   G+  T  G LPL +G+AVVDA+  V
Sbjct: 60  VLIAEYQASARGRHSRTWVSPPQAQISMSVLLSMPGMNLTDMGWLPLLSGIAVVDALRNV 119

Query: 116 TGVEAKLKWPNDVLVDTGKLAGILAEVA--SPAPTVVIGTGLNXXXXXXXXXXXXATSLA 173
             V A+LKWPNDVL+   K+AGILAEVA  +P P VV+G GLN            ATSL 
Sbjct: 120 AEVPAELKWPNDVLIGDKKVAGILAEVARTAPDPAVVVGIGLNVSLGVEELPVPTATSLL 179

Query: 174 MLTDAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDR 233
           +   + VDR  L+      LA +  +W             YRQ  GTLG  VR +LPGD+
Sbjct: 180 IEEASTVDRDTLVRAIARELATQFRAWESSKWDTSVLAAEYRQRCGTLGKRVRAVLPGDK 239

Query: 234 QLLGDAVDIDESGRLLID---SEGERITVAAGDVTHLRPA 270
           ++ G A DID SGR++I+   ++GE   VAAGD+THLR A
Sbjct: 240 EVFGIATDIDTSGRVVIEIEGTDGETFAVAAGDITHLRAA 279


>tr|A5WSJ4|A5WSJ4_MYCTF Tax_Id=336982 SubName: Full=Bifunctional
           protein birA: biotin operon repressor +
           biotin-[acetyl-CoA-carboxylase]
           synthetase;[Mycobacterium tuberculosis]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|A5U7V3|A5U7V3_MYCTA Tax_Id=419947 (birA)SubName: Full=Putative
           bifunctional protein BirA;[Mycobacterium tuberculosis]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|A1KNT1|A1KNT1_MYCBP Tax_Id=410289 (birA)SubName: Full=Possible
           bifunctional protein birA: biotin operon repressor +
           biotin--[acetyl-coa-carboxylase] synthetase;
           EC=6.3.4.15;[Mycobacterium bovis]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAANYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D6G369|D6G369_MYCTU Tax_Id=478435 SubName: Full=Bifunctional
           biotin biosynthesis protein birA;[Mycobacterium
           tuberculosis KZN 605]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D6FLI6|D6FLI6_MYCTU Tax_Id=611303 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase]
           ligase;[Mycobacterium tuberculosis CPHL_A]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAANYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D5Z8C4|D5Z8C4_MYCTU Tax_Id=537209 SubName:
           Full=Biotin-(Acetyl-CoA carboxylase)
           ligase;[Mycobacterium tuberculosis GM 1503]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D5YWN1|D5YWN1_MYCTU Tax_Id=515616 SubName: Full=Biotin operon
           repressor + biotin-[acetyl-CoA-carboxylase]
           synthetase;[Mycobacterium tuberculosis 02_1987]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D5Y8L2|D5Y8L2_MYCTU Tax_Id=520141 SubName: Full=Biotin operon
           repressor + biotin-[acetyl-CoA-carboxylase]
           synthetase;[Mycobacterium tuberculosis T85]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|A2VP75|A2VP75_MYCTU Tax_Id=348776 SubName: Full=Bifunctional
           protein birA : biotin operon repressor +
           biotin-[acetyl-CoA-carboxylase]
           synthetase;[Mycobacterium tuberculosis C]
          Length = 266

 Score =  223 bits (568), Expect = 2e-56
 Identities = 132/268 (49%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|A4KLH5|A4KLH5_MYCTU Tax_Id=395095 SubName: Full=Bifunctional
           protein birA : biotin operon repressor +
           biotin-[acetyl-CoA-carboxylase]
           synthetase;[Mycobacterium tuberculosis str. Haarlem]
          Length = 266

 Score =  223 bits (567), Expect = 2e-56
 Identities = 131/268 (48%), Positives = 161/268 (60%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+GR W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHGRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VR+ LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRIELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|C1B1A9|C1B1A9_RHOOB Tax_Id=632772 (birA)SubName: Full=Biotin
           protein ligase; EC=6.3.4.15;[Rhodococcus opacus]
          Length = 284

 Score =  221 bits (562), Expect = 9e-56
 Identities = 131/279 (46%), Positives = 167/279 (59%), Gaps = 11/279 (3%)

Query: 1   MNSDTERPALDADAIRSAVVR------PRGSWRSFDVVAETGSTNADLLARARSGTDING 54
           M +D  RP L+AD +R+A+VR       R  W   DVV ETGSTNADLL+RA + +D + 
Sbjct: 3   MWTDLNRPPLNADNLRAALVRGDDDSDTRKFWSRLDVVQETGSTNADLLSRAAT-SDCDR 61

Query: 55  AVLAAEHQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISA 114
            VL AE Q +GRGR+ R W +PP++QIAVS  +   G+     G LPL TGVAVVDA+ A
Sbjct: 62  HVLLAEFQGSGRGRHSRAWVSPPQAQIAVSALLTMPGMSVHDMGWLPLLTGVAVVDALRA 121

Query: 115 VTGVEAKLKWPNDVLVDTGKLAGILAEVA--SPAPTVVIGTGLNXXXXXXXXXXXXATSL 172
              V A+LKWPNDVL+D  K+AGILAEV+  +P P VV+G GLN            ATSL
Sbjct: 122 TAKVPAELKWPNDVLIDGRKVAGILAEVSATTPDPAVVVGIGLNVSLTRDELPVEHATSL 181

Query: 173 AMLTDAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGD 232
            +      DR  L+   L  +ADR   W             YR+  GTLG  VR  LPG 
Sbjct: 182 VLEGAEVSDRDTLVRAVLRAIADRWRQWHDANWDVTELAGAYRERCGTLGQRVRAELPGG 241

Query: 233 RQLLGDAVDIDESGRLLI--DSEGERITVAAGDVTHLRP 269
           R+L+G A D+D  GR++I  D + + + VAAGD+THLRP
Sbjct: 242 RELIGIATDVDAEGRVVIAPDGQPDTVAVAAGDITHLRP 280


>tr|D6F9S9|D6F9S9_MYCTU Tax_Id=611302 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase]
           ligase;[Mycobacterium tuberculosis T46]
          Length = 266

 Score =  221 bits (562), Expect = 9e-56
 Identities = 131/268 (48%), Positives = 160/268 (59%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+ R W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHSRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D5ZLF8|D5ZLF8_MYCTU Tax_Id=537210 SubName: Full=Bifunctional
           biotin biosynthesis protein birA;[Mycobacterium
           tuberculosis T17]
          Length = 266

 Score =  221 bits (562), Expect = 9e-56
 Identities = 131/268 (48%), Positives = 160/268 (59%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+ R W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHSRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D5YJP7|D5YJP7_MYCTU Tax_Id=520140 SubName: Full=Biotin operon
           repressor + biotin;[Mycobacterium tuberculosis EAS054]
          Length = 266

 Score =  221 bits (562), Expect = 9e-56
 Identities = 131/268 (48%), Positives = 160/268 (59%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+ R W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHSRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|D5XYV0|D5XYV0_MYCTU Tax_Id=515617 SubName: Full=Bifunctional
           biotin biosynthesis protein birA;[Mycobacterium
           tuberculosis T92]
          Length = 266

 Score =  221 bits (562), Expect = 9e-56
 Identities = 131/268 (48%), Positives = 160/268 (59%), Gaps = 9/268 (3%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  RP LD  ++R  ++     WR  DVVA+TGSTNADLLARA SG DI+G VL AEHQT
Sbjct: 5   DRLRPPLDERSLRDQLIGAGSGWRQLDVVAQTGSTNADLLARAASGADIDGVVLIAEHQT 64

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAIS---AVTGVEA 120
           AGRGR+ R W    R+QI +SVG+    VP  AWG L LA G+AV+D+++   AV   E 
Sbjct: 65  AGRGRHSRGWAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAET 124

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
            LKWPNDVL   GKLAGILAEVA   P VV+G GLN            ATSL  L  A  
Sbjct: 125 GLKWPNDVLARGGKLAGILAEVAQ--PFVVLGVGLN-VTQAPEEVDPDATSLLDLGVAAP 181

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ + +  L  L  R+  W             YR  S T+G+ VRV LPG + ++G A 
Sbjct: 182 DRNRIASRLLRELEARIIQW---RNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIAR 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
           DID+ GRL +D  G  + V+AGDV HLR
Sbjct: 239 DIDDQGRLCLDVGGRTVVVSAGDVVHLR 266


>tr|C3JG94|C3JG94_RHOER Tax_Id=596309 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase] ligase;
           EC=6.3.4.15;[Rhodococcus erythropolis SK121]
          Length = 284

 Score =  221 bits (562), Expect = 9e-56
 Identities = 129/280 (46%), Positives = 169/280 (60%), Gaps = 11/280 (3%)

Query: 1   MNSDTERPALDADAIRSAVVRP-----RGSWRSFDVVAETGSTNADLLARARSGTDINGA 55
           M +D  RP LD +A+R A+VR      R  W   DVV ETGSTNADLLARA +  D +  
Sbjct: 1   MWTDLNRPPLDGNALRRALVRSDNDDARVFWNRLDVVEETGSTNADLLARA-ADPDADRH 59

Query: 56  VLAAEHQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAV 115
           VL AE+Q + RGR+ R W +PP++QI++SV +   G+     G LPL +G+AVVDA+  V
Sbjct: 60  VLIAEYQASARGRHSRTWVSPPQAQISMSVLLSMPGMNLADMGWLPLLSGIAVVDALRNV 119

Query: 116 TGVEAKLKWPNDVLVDTGKLAGILAEVA--SPAPTVVIGTGLNXXXXXXXXXXXXATSLA 173
             V A+LKWPNDVL+   K+AGILAEVA  +P P VV+G GLN            ATSL 
Sbjct: 120 AEVPAELKWPNDVLIGDKKVAGILAEVARTAPDPAVVVGIGLNVSLGVEELPVPTATSLL 179

Query: 174 MLTDAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDR 233
           +   + VDR  L+      LA +  +W             YRQ  GTLG  VR +LPGD+
Sbjct: 180 IEEASTVDRDTLVRAIARELATQFRAWESSKWDTSVLAAEYRQRCGTLGKRVRAVLPGDK 239

Query: 234 QLLGDAVDIDESGRLLID---SEGERITVAAGDVTHLRPA 270
           ++ G A D+D SGR++I+   ++GE   VAAGD+THLR A
Sbjct: 240 EVFGIATDVDTSGRVVIEIEGTDGETFAVAAGDITHLRAA 279


>tr|Q9CCL3|Q9CCL3_MYCLE Tax_Id=1769 (birA)SubName: Full=Biotin
           apo-protein ligase;[Mycobacterium leprae]
          Length = 274

 Score =  219 bits (557), Expect = 4e-55
 Identities = 130/279 (46%), Positives = 162/279 (58%), Gaps = 16/279 (5%)

Query: 1   MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE 60
           M SD  +P LD  A+R+ ++     WR  DVV +TGSTNADLLARA SG DI+GAVL AE
Sbjct: 1   MGSDLLKPPLDPAALRAELIGTGLRWRQLDVVTQTGSTNADLLARAASGIDIDGAVLIAE 60

Query: 61  HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISA---VTG 117
           HQTAGRGR+GR W+  PR+QI +S+G+    VP   W  L LATGVAV+D ++    VTG
Sbjct: 61  HQTAGRGRHGRGWSASPRTQITMSIGVSIADVPVATWAWLSLATGVAVLDTVAPLIDVTG 120

Query: 118 VEAKLKWPNDVLV----DTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLA 173
           V+A LKWPNDVL       GKLAGILAEV    P +V+G GLN            ATSL 
Sbjct: 121 VDAGLKWPNDVLAGPPGSKGKLAGILAEVV--RPVIVVGVGLNVTQAPKEVDGPGATSLL 178

Query: 174 MLTDAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDR 233
            L     DR  L+   L  L  RV  W             YR  S  +G+ VR  LPG +
Sbjct: 179 DLGVPAPDREQLVCWLLRELDARVGQW---RSADPQLMADYRARSPIIGSRVRAELPGGK 235

Query: 234 QLLGDAVDIDESGRLLIDSE----GERITVAAGDVTHLR 268
            ++G    ID+ GRL + +E    G+ + ++AGDV HLR
Sbjct: 236 DVVGTVRGIDDQGRLCLKTEGPTKGQTVVISAGDVVHLR 274


>tr|B8ZUY1|B8ZUY1_MYCLB Tax_Id=561304 (birA)SubName: Full=Biotin
           apo-protein ligase;[Mycobacterium leprae]
          Length = 274

 Score =  219 bits (557), Expect = 4e-55
 Identities = 130/279 (46%), Positives = 162/279 (58%), Gaps = 16/279 (5%)

Query: 1   MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE 60
           M SD  +P LD  A+R+ ++     WR  DVV +TGSTNADLLARA SG DI+GAVL AE
Sbjct: 1   MGSDLLKPPLDPAALRAELIGTGLRWRQLDVVTQTGSTNADLLARAASGIDIDGAVLIAE 60

Query: 61  HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISA---VTG 117
           HQTAGRGR+GR W+  PR+QI +S+G+    VP   W  L LATGVAV+D ++    VTG
Sbjct: 61  HQTAGRGRHGRGWSASPRTQITMSIGVSIADVPVATWAWLSLATGVAVLDTVAPLIDVTG 120

Query: 118 VEAKLKWPNDVLV----DTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLA 173
           V+A LKWPNDVL       GKLAGILAEV    P +V+G GLN            ATSL 
Sbjct: 121 VDAGLKWPNDVLAGPPGSKGKLAGILAEVV--RPVIVVGVGLNVTQAPKEVDGPGATSLL 178

Query: 174 MLTDAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDR 233
            L     DR  L+   L  L  RV  W             YR  S  +G+ VR  LPG +
Sbjct: 179 DLGVPAPDREQLVCWLLRELDARVGQW---RSADPQLMADYRARSPIIGSRVRAELPGGK 235

Query: 234 QLLGDAVDIDESGRLLIDSE----GERITVAAGDVTHLR 268
            ++G    ID+ GRL + +E    G+ + ++AGDV HLR
Sbjct: 236 DVVGTVRGIDDQGRLCLKTEGPTKGQTVVISAGDVVHLR 274


>tr|B2HEK8|B2HEK8_MYCMM Tax_Id=216594 (birA)SubName:
           Full=Bifunctional protein BirA;[Mycobacterium marinum]
          Length = 276

 Score =  216 bits (551), Expect = 2e-54
 Identities = 136/279 (48%), Positives = 161/279 (57%), Gaps = 21/279 (7%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  R  LDA  +RS  +     WR  DVV ETGSTNADLLARA +G DI GAVL AEHQT
Sbjct: 5   DQLRLPLDASKLRSEAID--SGWRQLDVVDETGSTNADLLARAAAGADIEGAVLIAEHQT 62

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAV---TGVEA 120
           AGRGR GR W+   R+QI +SVG+   GVP+  WG L LATG+AVVD ++ +   T  +A
Sbjct: 63  AGRGRLGRGWSATARAQITMSVGVRVDGVPTATWGWLSLATGLAVVDTVTPLLDGTAAQA 122

Query: 121 KLKWPNDVLV----DTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLT 176
            LKWPNDVL       GKLAGILAEVA   P  VIG GLN            ATSL  L 
Sbjct: 123 GLKWPNDVLAGPPGSLGKLAGILAEVA--MPYAVIGIGLNVTQAPDEIAGPAATSLLDLG 180

Query: 177 DAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLL 236
               DR+ L    L  LA R++ +             YR  S T+G+ VR  LPG R+++
Sbjct: 181 VPAPDRNELAARLLRELAARIDEF---RRAHARLSADYRARSLTIGSRVRAQLPGGREIV 237

Query: 237 GDAVDIDESGRLLIDS-------EGERITVAAGDVTHLR 268
           G A DIDE GRL + +        GE + VAAGDV HLR
Sbjct: 238 GIARDIDEQGRLRLQTTPDEAGKSGETVVVAAGDVVHLR 276


>tr|A0PRJ0|A0PRJ0_MYCUA Tax_Id=362242 (birA)SubName:
           Full=Bifunctional protein BirA;[Mycobacterium ulcerans]
          Length = 276

 Score =  215 bits (548), Expect = 4e-54
 Identities = 135/279 (48%), Positives = 161/279 (57%), Gaps = 21/279 (7%)

Query: 4   DTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQT 63
           D  R  LDA  +RS  +     WR  DVV ETGSTNADLLARA +G DI GAVL AEHQT
Sbjct: 5   DQLRLPLDASKLRSEAID--SGWRQLDVVDETGSTNADLLARAAAGADIEGAVLIAEHQT 62

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAV---TGVEA 120
           AGRGR GR W+   R+QI +SVG+   GVP+  WG L LATG+AVVD ++ +   T  +A
Sbjct: 63  AGRGRLGRGWSATARAQITMSVGVRVDGVPTATWGWLSLATGLAVVDTVTPLLDGTAAQA 122

Query: 121 KLKWPNDVLV----DTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLT 176
            LKWPNDVL       GKLAGILAEVA   P  VIG GLN            ATSL  L 
Sbjct: 123 GLKWPNDVLAGLPGSLGKLAGILAEVA--MPYAVIGIGLNVTQAPDEIAGPAATSLLDLG 180

Query: 177 DAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLL 236
               DR+ +    L  LA R++ +             YR  S T+G+ VR  LPG R+++
Sbjct: 181 VPAPDRNEVAARLLRELAARIDEF---RRAHARLSADYRARSLTIGSRVRAQLPGGREIV 237

Query: 237 GDAVDIDESGRLLIDS-------EGERITVAAGDVTHLR 268
           G A DIDE GRL + +        GE + VAAGDV HLR
Sbjct: 238 GIARDIDEQGRLRLQTTPDEAGKSGETVVVAAGDVVHLR 276


>tr|B5HUZ7|B5HUZ7_9ACTO Tax_Id=463191 SubName: Full=Biotin
           apo-protein ligase;[Streptomyces sviceus ATCC 29083]
          Length = 290

 Score =  206 bits (524), Expect = 2e-51
 Identities = 126/275 (45%), Positives = 152/275 (55%), Gaps = 8/275 (2%)

Query: 3   SDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQ 62
           SD +RP L+A A+R  +VR  G W   +VVA TGSTN+DL+ARA +G    GAVL AE Q
Sbjct: 17  SDLDRPPLNAAALRRGLVREGGLWSGIEVVAGTGSTNSDLVARATAGKATEGAVLVAEEQ 76

Query: 63  TAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEAKL 122
           TAGRGR  RQW+ P RS +  SV ++   VP   WG LPL TGVAV   +S   GV+  L
Sbjct: 77  TAGRGRLDRQWSAPARSGLFFSVLLNPADVPVARWGWLPLLTGVAVATGLSRAAGVDTAL 136

Query: 123 KWPNDVLVDTG----KLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDA 178
           KWPND+LV  G    K  GILAE A     VV+G G+N            A SLA+    
Sbjct: 137 KWPNDLLVTVGGEERKAGGILAERAG-EDGVVVGVGINVTLREDELPVPTAGSLALAGAV 195

Query: 179 PVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSG--TLGTAVRVLLPGDRQLL 236
             DR  LL   L  L +  E W                 +G  TLG  VR  LPGDR L+
Sbjct: 196 STDRDPLLRAVLRSLEEWYERWRAAAGDPTVSGLQETYAAGCATLGRTVRAELPGDRALV 255

Query: 237 GDAVDIDESGRLLI-DSEGERITVAAGDVTHLRPA 270
           G+AV +D  GRL+I   EG +  V AGD+ HLRPA
Sbjct: 256 GEAVAVDGDGRLVIATEEGVQKPVGAGDIVHLRPA 290


>tr|D6KCF1|D6KCF1_9ACTO Tax_Id=645465 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase] ligase; Flags:
           Fragment;[Streptomyces sp. e14]
          Length = 296

 Score =  201 bits (512), Expect = 6e-50
 Identities = 126/275 (45%), Positives = 148/275 (53%), Gaps = 8/275 (2%)

Query: 3   SDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQ 62
           SD +RP L+A A+R A+VRP G W   +VV  TGSTNADL+A A SG    GAVL AE Q
Sbjct: 23  SDLDRPPLNATALRRALVRPGGLWSGLEVVQSTGSTNADLVAAAESGKAAEGAVLVAEAQ 82

Query: 63  TAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEAKL 122
           TA RGR  R+WT P RS +  SV +    VP   WG LPL TGVAV   ++   GV+  L
Sbjct: 83  TAARGRLDRRWTAPARSGLFFSVLLRPGDVPVARWGWLPLLTGVAVATGLARSAGVDTAL 142

Query: 123 KWPNDVLVDTG----KLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDA 178
           KWPND+LV  G    K  GILAE A     VVIG G+N            A SLA+    
Sbjct: 143 KWPNDLLVTVGGEERKAGGILAERAG-NDGVVIGVGVNVTLRADELPVPQAGSLALANAV 201

Query: 179 PVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSG--TLGTAVRVLLPGDRQLL 236
             DR  LL   L  L D    W                 +G  TLG  VR  LPGDR L+
Sbjct: 202 STDRDTLLRAVLRALEDWYGRWRTAGGDPSAAGLQEAYAAGCATLGRRVRAELPGDRSLI 261

Query: 237 GDAVDIDESGRL-LIDSEGERITVAAGDVTHLRPA 270
           G+AV +D  GRL L   +G +  V AGD+ HLRPA
Sbjct: 262 GEAVAVDGDGRLVLATQDGVQEPVGAGDIVHLRPA 296


>tr|Q5Z151|Q5Z151_NOCFA Tax_Id=37329 (birA)SubName: Full=Putative
           biotin-[acetyl-CoA carboxylase] holoenzyme
           synthetase/biotin operon repressor;[Nocardia farcinica]
          Length = 273

 Score =  199 bits (505), Expect = 4e-49
 Identities = 123/267 (46%), Positives = 153/267 (57%), Gaps = 8/267 (2%)

Query: 5   TERPALDADAIRSAVVRPRGSWRSFDVVAE-TGSTNADLLARARSGTDINGAVLAAEHQT 63
           + RP LD   +R  V  P  S  S   V E TGSTNADL+ARA S     G VL AE Q 
Sbjct: 9   SRRPPLDVTRLRRGVESPELSLFSRVAVVEATGSTNADLIARA-SDPGAAGTVLLAETQQ 67

Query: 64  AGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEAKLK 123
           AGRGR+ R WT+PPR+QIA+S+ +   G+     G LPL TGVAVVDA+ A  GV A+LK
Sbjct: 68  AGRGRHARSWTSPPRAQIAMSMLVRPRGLEPAVLGWLPLLTGVAVVDALRAAAGVPAELK 127

Query: 124 WPNDVLVDTGKLAGILAEVASP--APTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPVD 181
           WPNDVL+   K+AGILAEVA+    P VV+G G+N            A SL +   A VD
Sbjct: 128 WPNDVLIGGRKVAGILAEVAASGGTPAVVVGVGVNVSLSAAELPVPHAISLELAGAAQVD 187

Query: 182 RSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAVD 241
           R+A++   L   + R ++W             YR+   T+G  V   LPG R L G A  
Sbjct: 188 RTAVVLAILAEFSRRFDAWRQAGWDTTELAAAYRERCATIGAQVMAELPGGRTLTGIATG 247

Query: 242 IDESGRLLIDSEGERITVAAGDVTHLR 268
           ID++GRLLI  +     V+AGDVTHLR
Sbjct: 248 IDDAGRLLIGDD----AVSAGDVTHLR 270


>tr|D3CG31|D3CG31_9ACTO Tax_Id=648999 SubName:
           Full=Biotin/acetyl-CoA-carboxylase ligase;
           EC=6.3.4.15;[Micromonospora sp. L5]
          Length = 290

 Score =  196 bits (499), Expect = 2e-48
 Identities = 117/285 (41%), Positives = 159/285 (55%), Gaps = 20/285 (7%)

Query: 3   SDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQ 62
           +D +RP L A  +R A+V P G WR  +++AETGSTNAD++A AR+G +  G V+ AE Q
Sbjct: 7   TDLDRPPLSAARLRRALVAPHGPWRRLELLAETGSTNADVVAAARAG-EPEGLVVVAERQ 65

Query: 63  TAGRGRNGRQWTTPPRSQIAVSVGIDT---------TGVPSTAWGLLPLATGVAVVDAIS 113
           TAGRGR GR W +PPR+ +A SV +           + VP+T +G LPL  GVA+ +A+ 
Sbjct: 66  TAGRGRRGRVWQSPPRAGLATSVLLRPGEAVAERGWSPVPTTGYGWLPLLAGVALAEAVR 125

Query: 114 AVTGVEAKLKWPNDVLVDTGKLAGILAEVA----SPAPTVVIGTGLN----XXXXXXXXX 165
            +  ++A+LKWPND+LVD  K AG+LAE         P +V+G GLN             
Sbjct: 126 LLAELDARLKWPNDLLVDGAKCAGVLAEAVPGENDRPPAIVVGVGLNVTLRADELPENPT 185

Query: 166 XXXATSLAMLTDAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSG--TLGT 223
              ATSL +      DR  LL   L  LAD  E W                 +G  T+G 
Sbjct: 186 GLPATSLQLAGATATDRDPLLRALLRSLADWYERWRDAGGDAEASGLREAYLAGCATVGR 245

Query: 224 AVRVLLPGDRQLLGDAVDIDESGRLLIDSEGERITVAAGDVTHLR 268
            VRVLLP  R++ G A  +D  G+LL+++  E + +AAGDV HLR
Sbjct: 246 QVRVLLPDGREVHGTATGVDADGQLLVETGAETLRLAAGDVLHLR 290


>tr|D2PKN2|D2PKN2_KRIFD Tax_Id=479435 SubName:
           Full=Biotin/acetyl-CoA-carboxylase ligase;[Kribbella
           flavida]
          Length = 269

 Score =  195 bits (496), Expect = 4e-48
 Identities = 116/268 (43%), Positives = 146/268 (54%), Gaps = 2/268 (0%)

Query: 1   MNSDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAE 60
           M  D ERP LD   +R  +VRP   W   DV+ ET STNA + A A SG    G V+ AE
Sbjct: 1   MFGDLERPPLDEKFLRGRLVRPGSLWTQVDVLTETPSTNAVVAAAAASGAP-EGLVVTAE 59

Query: 61  HQTAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEA 120
           +Q++GRGR GR WTTPPRS +  SV +    VP+  W  L L   +AV  A+  V  + A
Sbjct: 60  YQSSGRGRLGRTWTTPPRSALLTSVLLRPATVPAVRWPWLGLLVPLAVASAVRRVAEIPA 119

Query: 121 KLKWPNDVLVDTGKLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDAPV 180
           ++KWPNDVLV+  KLAGIL E     P V++G GLN            ATSLA+   A  
Sbjct: 120 QVKWPNDVLVEDRKLAGILLERVD-GPAVIVGMGLNVTLRADERPHAAATSLALEGAATT 178

Query: 181 DRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLLGDAV 240
           DR+ +L   L  LA R + W             Y++ S T G  VRV LP  R L G A 
Sbjct: 179 DRATVLAATLRELATRYQEWVDADGDPAVVLPDYQELSATFGRRVRVELPDGRFLEGTAS 238

Query: 241 DIDESGRLLIDSEGERITVAAGDVTHLR 268
            +D  GRL++D+      +AAGDVTHLR
Sbjct: 239 GLDTDGRLVLDTADGPRPLAAGDVTHLR 266


>tr|A6WEY2|A6WEY2_KINRD Tax_Id=266940 SubName:
           Full=Biotin--acetyl-CoA-carboxylase ligase;[Kineococcus
           radiotolerans]
          Length = 270

 Score =  193 bits (490), Expect = 2e-47
 Identities = 125/273 (45%), Positives = 157/273 (57%), Gaps = 17/273 (6%)

Query: 3   SDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQ 62
           +D  RP L + A+R A+V P G W   DVVA TGSTNADLLA   +    +GAVL A+HQ
Sbjct: 6   NDLARPPLRSAALRRALVGP-GPWSRLDVVASTGSTNADLLADEDAP---DGAVLVADHQ 61

Query: 63  TAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEAKL 122
           T GRGR GR W+ PPRS +AVSV +     P   W LLPL TG+A VDA+ A+ GV  +L
Sbjct: 62  TGGRGRLGRTWSAPPRSGLAVSVLLRPQR-PVAEWSLLPLVTGLAAVDALEAL-GVRTRL 119

Query: 123 KWPNDVLVD----TGKLAGILAEVASPA--PTVVIGTGLNXXXXXXXXXXXXATSLAMLT 176
           KWPNDVLV+     GK+ GILAE  + A    VV+G G+N            ATSLA+  
Sbjct: 120 KWPNDVLVEGPDRPGKVCGILAEARTGAGGARVVLGAGINVSLRTEELPVDTATSLALAG 179

Query: 177 DAPVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSGTLGTAVRVLLPGDRQLL 236
               DR  +L  +L  L  RV++W             YR  S T+G  VR  LP    L 
Sbjct: 180 ARSCDRDTVLRRYLRALRARVDAW----GAGESPLGDYRALSATIGQDVRAHLPDGSVLE 235

Query: 237 GDAVDIDESGRLLID-SEGERITVAAGDVTHLR 268
             AVD+DE GRL+++ S G R +++A DV HLR
Sbjct: 236 ALAVDVDEEGRLVVEGSGGARTSLSAADVVHLR 268


>tr|D6ECE7|D6ECE7_STRLI Tax_Id=457428 SubName:
           Full=Biotin-[acetyl-CoA-carboxylase]
           ligase;[Streptomyces lividans TK24]
          Length = 291

 Score =  192 bits (489), Expect = 3e-47
 Identities = 124/275 (45%), Positives = 144/275 (52%), Gaps = 8/275 (2%)

Query: 3   SDTERPALDADAIRSAVVRPRGSWRSFDVVAETGSTNADLLARARSGTDINGAVLAAEHQ 62
           SD +RP L + A+R  +VR  G WR  DVV  TGSTN+DL+ARA  G    G VL AE Q
Sbjct: 18  SDLDRPPLSSTALRRGLVRDGGLWRQVDVVQRTGSTNSDLVARAAEGGLAEGVVLVAEEQ 77

Query: 63  TAGRGRNGRQWTTPPRSQIAVSVGIDTTGVPSTAWGLLPLATGVAVVDAISAVTGVEAKL 122
           +A RGR  RQWT P RS +  SV +    VP   WG LPL TGVAV   +S V GV+  L
Sbjct: 78  SAARGRLDRQWTAPARSGLFFSVLLRPAEVPVPRWGWLPLLTGVAVATGLSRVAGVDTAL 137

Query: 123 KWPNDVLVDTG----KLAGILAEVASPAPTVVIGTGLNXXXXXXXXXXXXATSLAMLTDA 178
           KWPND+LV  G    K  GILAE A     VVIG G+N            A SLA+    
Sbjct: 138 KWPNDLLVTVGDEERKAGGILAERAGD-DGVVIGVGINVSLRADELPVPRAGSLALAGAV 196

Query: 179 PVDRSALLTEFLTRLADRVESWXXXXXXXXXXXXXYRQCSG--TLGTAVRVLLPGDRQLL 236
             DR  LL   L  L D    W                 +G  TLG  VR  LPGDR L+
Sbjct: 197 NTDRDPLLRGVLRSLEDWYGRWRGAGGDPAASGLQGTYAAGCATLGRMVRAELPGDRSLV 256

Query: 237 GDAVDIDESGRL-LIDSEGERITVAAGDVTHLRPA 270
           G+AV +D  GRL L    G +  V AGD+ HLR A
Sbjct: 257 GEAVAVDGDGRLVLATGAGVQEPVGAGDIVHLRLA 291


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.315    0.131    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 1,966,255,947
Number of extensions: 76400411
Number of successful extensions: 227889
Number of sequences better than 10.0: 2318
Number of HSP's gapped: 226613
Number of HSP's successfully gapped: 2359
Length of query: 270
Length of database: 4,236,830,644
Length adjustment: 136
Effective length of query: 134
Effective length of database: 2,535,761,140
Effective search space: 339791992760
Effective search space used: 339791992760
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 79 (35.0 bits)