BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_2379
         (340 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|A0QUY3|A0QUY3_MYCS2 Tax_Id=246196 (leuB)SubName: Full=3-isopr...   668   0.0  
sp|A1T6Z4|LEU3_MYCVP Tax_Id=350058 (leuB)RecName: Full=3-isoprop...   570   e-160
sp|A4TE12|LEU3_MYCGI Tax_Id=350054 (leuB)RecName: Full=3-isoprop...   566   e-159
tr|D5Z7I2|D5Z7I2_MYCTU Tax_Id=537209 SubName: Full=3-isopropylma...   563   e-158
sp|P95313|LEU3_MYCTU Tax_Id=1773 (leuB)RecName: Full=3-isopropyl...   562   e-158
sp|A5U706|LEU3_MYCTA Tax_Id=419947 (leuB)RecName: Full=3-isoprop...   562   e-158
sp|Q1BAR4|LEU3_MYCSS Tax_Id=164756 (leuB)RecName: Full=3-isoprop...   562   e-158
sp|A1UE98|LEU3_MYCSK Tax_Id=189918 (leuB)RecName: Full=3-isoprop...   562   e-158
sp|A3PXQ2|LEU3_MYCSJ Tax_Id=164757 (leuB)RecName: Full=3-isoprop...   562   e-158
tr|C6DW54|C6DW54_MYCTK Tax_Id=478434 SubName: Full=3-isopropylma...   562   e-158
tr|A5WRP8|A5WRP8_MYCTF Tax_Id=336982 SubName: Full=3-isopropylma...   562   e-158
tr|D6G1H8|D6G1H8_MYCTU Tax_Id=478435 SubName: Full=3-isopropylma...   562   e-158
tr|D5YVT3|D5YVT3_MYCTU Tax_Id=515616 SubName: Full=3-isopropylma...   562   e-158
tr|A4KKQ1|A4KKQ1_MYCTU Tax_Id=395095 SubName: Full=3-isopropylma...   562   e-158
tr|A2VLW6|A2VLW6_MYCTU Tax_Id=348776 SubName: Full=3-isopropylma...   562   e-158
sp|C1AGB0|LEU3_MYCBT Tax_Id=561275 (leuB)RecName: Full=3-isoprop...   560   e-157
sp|A1KMY9|LEU3_MYCBP Tax_Id=410289 (leuB)RecName: Full=3-isoprop...   560   e-157
sp|P94929|LEU3_MYCBO Tax_Id=1765 (leuB)RecName: Full=3-isopropyl...   560   e-157
tr|D6FPW9|D6FPW9_MYCTU Tax_Id=611304 SubName: Full=3-isopropylma...   560   e-157
tr|D6FKN5|D6FKN5_MYCTU Tax_Id=611303 SubName: Full=3-isopropylma...   560   e-157
tr|D6F8D4|D6F8D4_MYCTU Tax_Id=611302 SubName: Full=3-isopropylma...   560   e-157
tr|D5XXZ8|D5XXZ8_MYCTU Tax_Id=515617 SubName: Full=3-isopropylma...   560   e-157
sp|B2HIH1|LEU3_MYCMM Tax_Id=216594 (leuB)RecName: Full=3-isoprop...   553   e-156
sp|Q73VI1|LEU3_MYCPA Tax_Id=1770 (leuB)RecName: Full=3-isopropyl...   552   e-155
sp|A0QJC2|LEU3_MYCA1 Tax_Id=243243 (leuB)RecName: Full=3-isoprop...   552   e-155
tr|B1MDR0|B1MDR0_MYCA9 Tax_Id=561007 SubName: Full=3-isopropylma...   551   e-155
tr|D5PIX9|D5PIX9_9MYCO Tax_Id=525368 (leuB)SubName: Full=3-isopr...   550   e-154
sp|A0PPY6|LEU3_MYCUA Tax_Id=362242 (leuB)RecName: Full=3-isoprop...   549   e-154
tr|D5YIV8|D5YIV8_MYCTU Tax_Id=520140 SubName: Full=3-isopropylma...   547   e-154
sp|O33117|LEU3_MYCLE Tax_Id=1769 (leuB)RecName: Full=3-isopropyl...   529   e-148
sp|B8ZS15|LEU3_MYCLB Tax_Id=561304 (leuB)RecName: Full=3-isoprop...   529   e-148
sp|Q5YRX2|LEU3_NOCFA Tax_Id=37329 (leuB)RecName: Full=3-isopropy...   518   e-145
tr|D0LC42|D0LC42_GORB4 Tax_Id=526226 SubName: Full=3-isopropylma...   511   e-143
sp|C1B2M3|LEU3_RHOOB Tax_Id=632772 (leuB)RecName: Full=3-isoprop...   490   e-136
sp|Q0S2H1|LEU3_RHOSR Tax_Id=101510 (leuB)RecName: Full=3-isoprop...   489   e-136
sp|A4FMQ2|LEU3_SACEN Tax_Id=405948 (leuB)RecName: Full=3-isoprop...   485   e-135
tr|C6WG57|C6WG57_ACTMD Tax_Id=446462 SubName: Full=3-isopropylma...   484   e-135
sp|C0ZXM4|LEU3_RHOE4 Tax_Id=234621 (leuB)RecName: Full=3-isoprop...   475   e-132
tr|C8XEL3|C8XEL3_NAKMY Tax_Id=479431 SubName: Full=3-isopropylma...   474   e-132
tr|C3JSJ7|C3JSJ7_RHOER Tax_Id=596309 (leuB)SubName: Full=3-isopr...   473   e-131
tr|A3TR55|A3TR55_9MICO Tax_Id=313589 SubName: Full=3-isopropylma...   473   e-131
tr|C5V883|C5V883_9CORY Tax_Id=553207 (leuB)SubName: Full=3-isopr...   472   e-131
tr|C2CMU7|C2CMU7_CORST Tax_Id=525268 (leuB)SubName: Full=3-isopr...   471   e-131
tr|C0E6S4|C0E6S4_9CORY Tax_Id=566549 SubName: Full=Putative unch...   470   e-130
tr|C7MXE6|C7MXE6_SACVD Tax_Id=471857 SubName: Full=3-isopropylma...   469   e-130

>tr|A0QUY3|A0QUY3_MYCS2 Tax_Id=246196 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Mycobacterium smegmatis]
          Length = 340

 Score =  668 bits (1723), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MSSNLKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEE 60
           MSSNLKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEE
Sbjct: 1   MSSNLKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEE 60

Query: 61  LRGYDAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPID 120
           LRGYDAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPID
Sbjct: 61  LRGYDAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPID 120

Query: 121 FVVVREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLV 180
           FVVVREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLV
Sbjct: 121 FVVVREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLV 180

Query: 181 HKTNVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDI 240
           HKTNVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDI
Sbjct: 181 HKTNVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDI 240

Query: 241 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLS 300
           ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLS
Sbjct: 241 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLS 300

Query: 301 HVGQTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           HVGQTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL
Sbjct: 301 HVGQTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340


>sp|A1T6Z4|LEU3_MYCVP Tax_Id=350058 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium vanbaalenii]
          Length = 336

 Score =  570 bits (1468), Expect = e-160
 Identities = 281/332 (84%), Positives = 305/332 (91%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           ++LAVIAGDGIGPEVI EA+ VLDAVLPGVEKTEYDLGAR+YH TGE+L D  +EEL+G+
Sbjct: 1   MRLAVIAGDGIGPEVITEALKVLDAVLPGVEKTEYDLGARQYHKTGEVLPDSVLEELKGH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSG+LERG+LL++RF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGLLERGLLLRIRFELDHHINLRPARLYPGVQSPLAGNPEIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTPHE+ATEVSVNTAFGV R V+DAF RAQ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGNGGAIRVGTPHEIATEVSVNTAFGVRRAVQDAFGRAQQRRKHLTLVHKNN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL  AGSLW RTV  VA EYPDVEVAYQH+DAATIHMVTDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTNAGSLWWRTVQTVAAEYPDVEVAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDAT T+PSMFEPVHGSAPDIAGQGIADPTAAVMSV LLL+H+ +
Sbjct: 241 AAAVCGGIGLAASGNIDATLTHPSMFEPVHGSAPDIAGQGIADPTAAVMSVSLLLAHMAE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERI 336
            +AAARVDKAV+EHLATRGDEKLST+AVGERI
Sbjct: 301 VDAAARVDKAVAEHLATRGDEKLSTAAVGERI 332


>sp|A4TE12|LEU3_MYCGI Tax_Id=350054 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium gilvum]
          Length = 336

 Score =  566 bits (1459), Expect = e-159
 Identities = 278/332 (83%), Positives = 305/332 (91%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVIAGDGIGPEVI EA+ VLDAV+PGVEKTEYDLGAR YH TGE+L D  ++EL+G+
Sbjct: 1   MKLAVIAGDGIGPEVIGEALRVLDAVVPGVEKTEYDLGARLYHRTGEVLPDSVLDELKGH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPS+PSGVLERG+LL++RF LDHH+NLRPGRLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSMPSGVLERGLLLRIRFELDHHINLRPGRLYPGVQSPLAGNPEIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTPHE+ATEVSVNTA+GV RVV+DAF RAQ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGNGGAIRVGTPHEIATEVSVNTAYGVRRVVQDAFKRAQQRRKHLTLVHKNN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL  AGSLW RTV  VA EYP+VEVAYQH+DAATIHMVTDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTNAGSLWWRTVQAVAAEYPEVEVAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDAT TNPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLL+H+ +
Sbjct: 241 AAAVCGGIGLAASGNIDATLTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAHMAE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERI 336
            +AAARVDKAV+EHLATRGDEKLST+ VG+RI
Sbjct: 301 IDAAARVDKAVAEHLATRGDEKLSTTQVGDRI 332


>tr|D5Z7I2|D5Z7I2_MYCTU Tax_Id=537209 SubName:
           Full=3-isopropylmalate dehydrogenase;[Mycobacterium
           tuberculosis GM 1503]
          Length = 342

 Score =  563 bits (1451), Expect = e-158
 Identities = 279/339 (82%), Positives = 305/339 (89%)

Query: 2   SSNLKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEEL 61
           S+ +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + EL
Sbjct: 4   STPMKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAEL 63

Query: 62  RGYDAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDF 121
           R +DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDF
Sbjct: 64  RNHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDF 123

Query: 122 VVVREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVH 181
           VVVREGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVH
Sbjct: 124 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 183

Query: 182 KTNVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDII 241
           KTNVL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 184 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 243

Query: 242 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSH 301
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH
Sbjct: 244 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 303

Query: 302 VGQTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           +G+ +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 304 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 342


>sp|P95313|LEU3_MYCTU Tax_Id=1773 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium tuberculosis]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 278/336 (82%), Positives = 303/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|A5U706|LEU3_MYCTA Tax_Id=419947 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium tuberculosis]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 278/336 (82%), Positives = 303/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|Q1BAR4|LEU3_MYCSS Tax_Id=164756 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium sp.]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 275/336 (81%), Positives = 304/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           + LA+IAGDGIGPEVI EAV VLDAVLP VEKT YDLGARRYHATGE+L D  +EEL+ +
Sbjct: 1   MNLAIIAGDGIGPEVIGEAVKVLDAVLPEVEKTTYDLGARRYHATGEILPDSVLEELKVH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL++RFALDHH+NLRP +LY GVTGPL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRIRFALDHHINLRPAKLYSGVTGPLAGNPEIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+RVGTPHEVATEVS+NTAFGV RVV DAF RAQ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGTGGAIRVGTPHEVATEVSLNTAFGVRRVVEDAFRRAQQRRKHLTLVHKNN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG+LW RTV  V  EYPDVE+AYQH+D+A IH+VTDPGRFDVIVTDNLFGDI+TDL
Sbjct: 181 VLTFAGALWWRTVQEVGAEYPDVEIAYQHVDSAMIHIVTDPGRFDVIVTDNLFGDIVTDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLL+HVG+
Sbjct: 241 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHVGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           T+AAARVDKAV  HL++RGD++L T+AVG+RI  LL
Sbjct: 301 TDAAARVDKAVEAHLSSRGDQELGTAAVGDRIVGLL 336


>sp|A1UE98|LEU3_MYCSK Tax_Id=189918 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium sp.]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 275/336 (81%), Positives = 304/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           + LA+IAGDGIGPEVI EAV VLDAVLP VEKT YDLGARRYHATGE+L D  +EEL+ +
Sbjct: 1   MNLAIIAGDGIGPEVIGEAVKVLDAVLPEVEKTTYDLGARRYHATGEILPDSVLEELKVH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL++RFALDHH+NLRP +LY GVTGPL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRIRFALDHHINLRPAKLYSGVTGPLAGNPEIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+RVGTPHEVATEVS+NTAFGV RVV DAF RAQ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGTGGAIRVGTPHEVATEVSLNTAFGVRRVVEDAFRRAQQRRKHLTLVHKNN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG+LW RTV  V  EYPDVE+AYQH+D+A IH+VTDPGRFDVIVTDNLFGDI+TDL
Sbjct: 181 VLTFAGALWWRTVQEVGAEYPDVEIAYQHVDSAMIHIVTDPGRFDVIVTDNLFGDIVTDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLL+HVG+
Sbjct: 241 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHVGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           T+AAARVDKAV  HL++RGD++L T+AVG+RI  LL
Sbjct: 301 TDAAARVDKAVEAHLSSRGDQELGTAAVGDRIVGLL 336


>sp|A3PXQ2|LEU3_MYCSJ Tax_Id=164757 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium sp.]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 275/336 (81%), Positives = 304/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           + LA+IAGDGIGPEVI EAV VLDAVLP VEKT YDLGARRYHATGE+L D  +EEL+ +
Sbjct: 1   MNLAIIAGDGIGPEVIGEAVKVLDAVLPEVEKTTYDLGARRYHATGEILPDSVLEELKVH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL++RFALDHH+NLRP +LY GVTGPL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRIRFALDHHINLRPAKLYSGVTGPLAGNPEIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+RVGTPHEVATEVS+NTAFGV RVV DAF RAQ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGTGGAIRVGTPHEVATEVSLNTAFGVRRVVEDAFRRAQQRRKHLTLVHKNN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG+LW RTV  V  EYPDVE+AYQH+D+A IH+VTDPGRFDVIVTDNLFGDI+TDL
Sbjct: 181 VLTFAGALWWRTVQEVGAEYPDVEIAYQHVDSAMIHIVTDPGRFDVIVTDNLFGDIVTDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLL+HVG+
Sbjct: 241 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHVGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           T+AAARVDKAV  HL++RGD++L T+AVG+RI  LL
Sbjct: 301 TDAAARVDKAVEAHLSSRGDQELGTAAVGDRIVGLL 336


>tr|C6DW54|C6DW54_MYCTK Tax_Id=478434 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 278/336 (82%), Positives = 303/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|A5WRP8|A5WRP8_MYCTF Tax_Id=336982 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 278/336 (82%), Positives = 303/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|D6G1H8|D6G1H8_MYCTU Tax_Id=478435 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis KZN 605]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 278/336 (82%), Positives = 303/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|D5YVT3|D5YVT3_MYCTU Tax_Id=515616 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis 02_1987]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 278/336 (82%), Positives = 303/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|A4KKQ1|A4KKQ1_MYCTU Tax_Id=395095 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis str. Haarlem]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 278/336 (82%), Positives = 303/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|A2VLW6|A2VLW6_MYCTU Tax_Id=348776 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis C]
          Length = 336

 Score =  562 bits (1448), Expect = e-158
 Identities = 278/336 (82%), Positives = 303/336 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|C1AGB0|LEU3_MYCBT Tax_Id=561275 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium bovis]
          Length = 336

 Score =  560 bits (1442), Expect = e-157
 Identities = 277/336 (82%), Positives = 302/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL  AG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|A1KMY9|LEU3_MYCBP Tax_Id=410289 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium bovis]
          Length = 336

 Score =  560 bits (1442), Expect = e-157
 Identities = 277/336 (82%), Positives = 302/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL  AG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|P94929|LEU3_MYCBO Tax_Id=1765 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium bovis]
          Length = 336

 Score =  560 bits (1442), Expect = e-157
 Identities = 277/336 (82%), Positives = 302/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL  AG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|D6FPW9|D6FPW9_MYCTU Tax_Id=611304 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis K85]
          Length = 336

 Score =  560 bits (1442), Expect = e-157
 Identities = 277/336 (82%), Positives = 302/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL  AG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|D6FKN5|D6FKN5_MYCTU Tax_Id=611303 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis CPHL_A]
          Length = 336

 Score =  560 bits (1442), Expect = e-157
 Identities = 277/336 (82%), Positives = 302/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL  AG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|D6F8D4|D6F8D4_MYCTU Tax_Id=611302 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis T46]
          Length = 336

 Score =  560 bits (1442), Expect = e-157
 Identities = 277/336 (82%), Positives = 302/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKIN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|D5XXZ8|D5XXZ8_MYCTU Tax_Id=515617 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis T92]
          Length = 336

 Score =  560 bits (1442), Expect = e-157
 Identities = 277/336 (82%), Positives = 302/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKIN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            +AAARVD+AV  HLATRG E+L+TS VGERI + L
Sbjct: 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|B2HIH1|LEU3_MYCMM Tax_Id=216594 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium marinum]
          Length = 339

 Score =  553 bits (1426), Expect = e-156
 Identities = 275/339 (81%), Positives = 304/339 (89%), Gaps = 3/339 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA++AGDGIGPEV+A+AV VLD V PGVEKT YDLGARR+HATGE+L D  I ELR +
Sbjct: 1   MKLAIVAGDGIGPEVVAQAVKVLDVVQPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLV---GNPPIDF 121
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRPGRLYPGV  PL    GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120

Query: 122 VVVREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVH 181
           VVVREGTEGPYTGNGGA+RVGT +EVATEVSVNTAFGV RVVRDAF RA  RRKHLTLVH
Sbjct: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180

Query: 182 KTNVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDII 241
           K NVL FAGSLW RTV  + +EYPDVE+AYQH+DAATIHMVTDPGRFDVIVTDNLFGDII
Sbjct: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240

Query: 242 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSH 301
           TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLL+H
Sbjct: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAH 300

Query: 302 VGQTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           +G  +AA+RVD+AV  +LATRG+E+L+T+AVGERI + L
Sbjct: 301 LGLDDAASRVDRAVEGYLATRGNERLATAAVGERIAAAL 339


>sp|Q73VI1|LEU3_MYCPA Tax_Id=1770 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium paratuberculosis]
          Length = 336

 Score =  552 bits (1423), Expect = e-155
 Identities = 275/336 (81%), Positives = 301/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIGPEV AEA+ VLDAVLPGV+KTEYDLGARRYHATGELL D  I+ELR +
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRPGRLYPGV+ PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVSSPLAGNPDIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+RVGTP+EVATEVS NTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGTGGAIRVGTPNEVATEVSQNTAFGVRRVVVDAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LWSR V  V ++YPDVEVAYQHIDAATI MVTDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGKLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           +AAVCGGIGLAASGNID TRTNPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLL+H+G+
Sbjct: 241 SAAVCGGIGLAASGNIDGTRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
             AA RVD+AV  +LATRG+E+ +T+ VGERI + L
Sbjct: 301 DAAATRVDRAVERYLATRGNERPATTEVGERIAAAL 336


>sp|A0QJC2|LEU3_MYCA1 Tax_Id=243243 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium avium]
          Length = 336

 Score =  552 bits (1422), Expect = e-155
 Identities = 274/336 (81%), Positives = 301/336 (89%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIGPEV AEA+ VLDAVLPGV+KTEYDLGARRYHATGELL D  I+ELR +
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRPGRLYPGV+ PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVSSPLAGNPDIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+RVGTP+EVATEVS NTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGTGGAIRVGTPNEVATEVSQNTAFGVRRVVVDAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LWSR V  V ++YPDVEVAYQHIDAATI MVTDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGKLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           +AAVCGGIGLAASGNID TRTNPSMFEPVHGSAPDIAGQG+ADPTAA+MSV LLL+H+G+
Sbjct: 241 SAAVCGGIGLAASGNIDGTRTNPSMFEPVHGSAPDIAGQGVADPTAAIMSVALLLAHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
             AA RVD+AV  +LATRG+E+ +T+ VGERI + L
Sbjct: 301 DAAATRVDRAVERYLATRGNERPATTEVGERIAAAL 336


>tr|B1MDR0|B1MDR0_MYCA9 Tax_Id=561007 SubName:
           Full=3-isopropylmalate dehydrogenase
           (Leu3);[Mycobacterium abscessus]
          Length = 337

 Score =  551 bits (1421), Expect = e-155
 Identities = 272/335 (81%), Positives = 303/335 (90%)

Query: 6   KLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGYD 65
           KLA+IAGDGIGPEVI EAV VLDAVLPGV+KTEYDLGARRY ATGEL+ D  ++ELRG+D
Sbjct: 3   KLAIIAGDGIGPEVIGEAVKVLDAVLPGVDKTEYDLGARRYLATGELMPDSVLDELRGHD 62

Query: 66  AILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVVR 125
           AILLGAIGDP+VPSGVLERG+LL  RFALDHH+NLRP +LYPGVTGPL GNP ID VVVR
Sbjct: 63  AILLGAIGDPAVPSGVLERGLLLNTRFALDHHINLRPAKLYPGVTGPLAGNPAIDLVVVR 122

Query: 126 EGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTNV 185
           EGTEGPYTGNGGA+RV TPHEVATEVS+NT FGVERVVR+AF RA+ R K+LTLVHK NV
Sbjct: 123 EGTEGPYTGNGGAIRVDTPHEVATEVSLNTRFGVERVVRNAFERAEARSKNLTLVHKNNV 182

Query: 186 LAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDLA 245
           L +AG+LW+RTV+ VA EYPDV+V+YQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 
Sbjct: 183 LKYAGTLWTRTVNEVAAEYPDVQVSYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDLT 242

Query: 246 AAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQT 305
           AAV GGIGLAASGNID +  NPSMFEPVHGSAPDIAGQGIADPTAA++SV LLL H+G+T
Sbjct: 243 AAVTGGIGLAASGNIDGSGKNPSMFEPVHGSAPDIAGQGIADPTAAIVSVSLLLDHLGET 302

Query: 306 EAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           EAAARV++AV +HLATRG+EKLSTSA G+RI S L
Sbjct: 303 EAAARVERAVEQHLATRGEEKLSTSATGDRIASFL 337


>tr|D5PIX9|D5PIX9_9MYCO Tax_Id=525368 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Mycobacterium parascrofulaceum ATCC
           BAA-614]
          Length = 336

 Score =  550 bits (1416), Expect = e-154
 Identities = 273/332 (82%), Positives = 300/332 (90%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIGPEV AEA+ VLDAVLPGVEKT+YDLGARR+HA+GELL +  + ELR +
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLDAVLPGVEKTDYDLGARRFHASGELLPESVLGELRQH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHHVNLRPGRLYPGV+ PL G+P IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHVNLRPGRLYPGVSSPLAGDPHIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+R GTPHEVATEVS+NTAFGV RVV DAF RAQ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGTGGAIRTGTPHEVATEVSLNTAFGVRRVVADAFERAQRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LWSR V  V ++YPDVEVAYQHIDAATI MVTDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGKLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLL+H+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERI 336
            +AA+RVD+AV  +LATRG E+ +T+ VGERI
Sbjct: 301 DDAASRVDRAVEAYLATRGSERPATTEVGERI 332


>sp|A0PPY6|LEU3_MYCUA Tax_Id=362242 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium ulcerans]
          Length = 339

 Score =  549 bits (1415), Expect = e-154
 Identities = 272/339 (80%), Positives = 303/339 (89%), Gaps = 3/339 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA++AGDGIGPEV+A+AV +LD V PGVEKT YDLGARR+HATGE+L D  I ELR +
Sbjct: 1   MKLAIVAGDGIGPEVVAQAVKILDVVQPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLV---GNPPIDF 121
           DAILLGAIGDPSVPSGVLERG+LL+LRF LD+H+NLRPGRLYPGV  PL    GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDYHINLRPGRLYPGVKSPLALEPGNPEIDF 120

Query: 122 VVVREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVH 181
           VVVREGTEGPYTGNGGA+RVGT +EVATEVSVNTAFGV RVVRDAF RA  RRKHLTLVH
Sbjct: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180

Query: 182 KTNVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDII 241
           K NVL FAGSLW RTV  + +EYPDVE+AYQH+DAATIHMVTDPGRFDVIVTDNLFGDII
Sbjct: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240

Query: 242 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSH 301
           TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLL+H
Sbjct: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAH 300

Query: 302 VGQTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           +G  + A+RVD+AV  +LATRG+E+L+T+AVGERI + L
Sbjct: 301 LGLDDTASRVDRAVEGYLATRGNERLATAAVGERIAAAL 339


>tr|D5YIV8|D5YIV8_MYCTU Tax_Id=520140 SubName:
           Full=3-isopropylmalate dehydrogenase; Flags:
           Fragment;[Mycobacterium tuberculosis EAS054]
          Length = 338

 Score =  547 bits (1410), Expect = e-154
 Identities = 273/333 (81%), Positives = 296/333 (88%), Gaps = 1/333 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D  + ELR +
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV  PL GNP IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct: 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEK-LSTSAVGERI 336
            +AAARVD+AV  HLATRG    L  +  GERI
Sbjct: 301 HDAAARVDRAVEAHLATRGQRNGLPPAMSGERI 333


>sp|O33117|LEU3_MYCLE Tax_Id=1769 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium leprae]
          Length = 336

 Score =  529 bits (1362), Expect = e-148
 Identities = 258/336 (76%), Positives = 294/336 (87%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+I GDGIGPEV+A+AV +LD VLPGV+KT YDLGARRYH TGELL +  + ELR +
Sbjct: 1   MKLAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGA+GDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV   L G P IDFVVV
Sbjct: 61  DAILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLAGKPDIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+RVGTP+EVATEVSVNTAFGV RVV+DAF RA+ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGTGGAIRVGTPNEVATEVSVNTAFGVRRVVQDAFERARQRRKHLTLVHKNN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL +AG+LW R V  V ++YPDVEV YQHIDAATI++VT+P RFDVIVTDNLFGDIITDL
Sbjct: 181 VLTYAGTLWCRIVQEVGEKYPDVEVVYQHIDAATIYLVTEPSRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGI LAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MS+ LLL+H+G+
Sbjct: 241 AAAVCGGIALAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSLALLLAHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            E AAR+D+AV+ +LATRG+ + ST  VGERI + L
Sbjct: 301 DEPAARLDQAVASYLATRGNGRFSTGEVGERIAAAL 336


>sp|B8ZS15|LEU3_MYCLB Tax_Id=561304 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium leprae]
          Length = 336

 Score =  529 bits (1362), Expect = e-148
 Identities = 258/336 (76%), Positives = 294/336 (87%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLA+I GDGIGPEV+A+AV +LD VLPGV+KT YDLGARRYH TGELL +  + ELR +
Sbjct: 1   MKLAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGA+GDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV   L G P IDFVVV
Sbjct: 61  DAILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLAGKPDIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+RVGTP+EVATEVSVNTAFGV RVV+DAF RA+ RRKHLTLVHK N
Sbjct: 121 REGTEGPYTGTGGAIRVGTPNEVATEVSVNTAFGVRRVVQDAFERARQRRKHLTLVHKNN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL +AG+LW R V  V ++YPDVEV YQHIDAATI++VT+P RFDVIVTDNLFGDIITDL
Sbjct: 181 VLTYAGTLWCRIVQEVGEKYPDVEVVYQHIDAATIYLVTEPSRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAVCGGI LAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MS+ LLL+H+G+
Sbjct: 241 AAAVCGGIALAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSLALLLAHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
            E AAR+D+AV+ +LATRG+ + ST  VGERI + L
Sbjct: 301 DEPAARLDQAVASYLATRGNGRFSTGEVGERIAAAL 336


>sp|Q5YRX2|LEU3_NOCFA Tax_Id=37329 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Nocardia farcinica]
          Length = 335

 Score =  518 bits (1335), Expect = e-145
 Identities = 262/332 (78%), Positives = 287/332 (86%), Gaps = 1/332 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIGPEVIAEA+ VLD V+PGVEKTEYDLGA+RYHATGE+L D  + ELR +
Sbjct: 1   MKLAVIPGDGIGPEVIAEALKVLDVVVPGVEKTEYDLGAKRYHATGEILPDSVLPELREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL+ RF LDHHVNLRP RL+ GV  PL G P IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRTRFELDHHVNLRPSRLFTGVRSPLAGAPDIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTG GGA+RV TPHEVATEVS NT FG+ERVVR AFA+AQ RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGTGGAIRVRTPHEVATEVSTNTRFGIERVVRYAFAKAQARRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAGSLW RTVD V  E+P+V VAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL
Sbjct: 181 VLTFAGSLWQRTVDEVGAEFPEVTVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAGQ  ADPTAA++SV LLL+H+G 
Sbjct: 241 AAAVSGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQSKADPTAAILSVSLLLNHLGD 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERI 336
           TEAAAR+D AV++ LA R     ST  +G+RI
Sbjct: 301 TEAAARIDAAVAKDLAARSG-TASTVEIGDRI 331


>tr|D0LC42|D0LC42_GORB4 Tax_Id=526226 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Gordonia bronchialis]
          Length = 337

 Score =  511 bits (1315), Expect = e-143
 Identities = 255/336 (75%), Positives = 289/336 (86%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVIAGDGIGPEVI EA+ VL  V+P V+ TE+DLGARRYH  GELL+D  ++ LR +
Sbjct: 1   MKLAVIAGDGIGPEVIGEALEVLKTVVPEVDTTEFDLGARRYHRNGELLTDADLDSLREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSVPSGVLERG+LL +RFALDHHVNLRP R  PGV  PL G+P IDFVVV
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLTMRFALDHHVNLRPSRRLPGVPTPLAGDPDIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTP EVATEVSVNT FGVERVVR+AF RA  RRKHLTLVHKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPQEVATEVSVNTRFGVERVVRNAFERAAKRRKHLTLVHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL FAGSLW+R V+ +  E+PDV  AY H+DAATI++VTDPGRFDVIVTDNLFGDIITD+
Sbjct: 181 VLTFAGSLWARAVEEIGTEFPDVTTAYCHVDAATIYLVTDPGRFDVIVTDNLFGDIITDI 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           AAAV GGIGLAASGNIDAT TNPSMFEPVHGSAPDIAGQG ADPTAA++SV LLL H+G+
Sbjct: 241 AAAVSGGIGLAASGNIDATGTNPSMFEPVHGSAPDIAGQGKADPTAAILSVALLLDHLGE 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           ++AA RV++AV++ LA RG   LST+ VG+RIR  L
Sbjct: 301 SDAARRVEQAVADDLAERGGSTLSTAEVGKRIRERL 336


>sp|C1B2M3|LEU3_RHOOB Tax_Id=632772 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Rhodococcus opacus]
          Length = 336

 Score =  490 bits (1261), Expect = e-136
 Identities = 246/336 (73%), Positives = 281/336 (83%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIG EV AEA+ VL  ++P +E TEYDLGARRY+ATGELL D  +  +R +
Sbjct: 1   MKLAVIPGDGIGVEVTAEALKVLRKLVPDLETTEYDLGARRYNATGELLPDADLAAIREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSV  GVLERG+LL +RFALDHHVNLRP +LYPG   PL   P IDFVVV
Sbjct: 61  DAILLGAIGDPSVTPGVLERGLLLNMRFALDHHVNLRPSQLYPGSKSPLAAQPDIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTPHE+ATEVS+NT FG ERVVR AFA AQ RRKH+TL+HKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPHEIATEVSINTWFGAERVVRYAFALAQTRRKHVTLIHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL+ AG++W+R V+ V+ EYPDVE AY HIDAATI+MVTDP RFDVIVTDNLFGDIITDL
Sbjct: 181 VLSNAGAIWTRAVETVSAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           A AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAGQGIADPTAA++S  LLL H+G+
Sbjct: 241 AGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAALLLRHLGR 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
              AAR++ AV   LA+RGD K+ TS VG+RI + L
Sbjct: 301 DGDAARIETAVEADLASRGDSKVVTSEVGDRIAAAL 336


>sp|Q0S2H1|LEU3_RHOSR Tax_Id=101510 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Rhodococcus sp.]
          Length = 336

 Score =  489 bits (1258), Expect = e-136
 Identities = 245/336 (72%), Positives = 281/336 (83%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIG EV AEA+ VL  ++P ++ TEYDLGARRY+ATGELL D  +  +R +
Sbjct: 1   MKLAVIPGDGIGVEVTAEALKVLRKLVPDLQTTEYDLGARRYNATGELLPDADLAAIREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGAIGDPSV  GVLERG+LL +RFALDHHVNLRP +LYPG   PL   P IDFVVV
Sbjct: 61  DAILLGAIGDPSVTPGVLERGLLLNMRFALDHHVNLRPSQLYPGSKSPLAAQPDIDFVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
           REGTEGPYTGNGGA+RVGTPHE+ATEVS+NT FG ERVVR AFA AQ RRKH+TL+HKTN
Sbjct: 121 REGTEGPYTGNGGAIRVGTPHEIATEVSINTWFGAERVVRYAFALAQTRRKHVTLIHKTN 180

Query: 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
           VL+ AG++W+R V+ V+ EYPDVE AY HIDAATI+MVTDP RFDVIVTDNLFGDIITDL
Sbjct: 181 VLSNAGAIWTRAVETVSAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDIITDL 240

Query: 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
           A AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAGQGIADPTAA++S  LLL H+G+
Sbjct: 241 AGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAALLLRHLGR 300

Query: 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
              AAR++ AV   LA+RGD K+ TS VG+RI + L
Sbjct: 301 DGDAARIEAAVEADLASRGDSKVVTSEVGDRIAAAL 336


>sp|A4FMQ2|LEU3_SACEN Tax_Id=405948 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Saccharopolyspora erythraea]
          Length = 347

 Score =  485 bits (1249), Expect = e-135
 Identities = 248/338 (73%), Positives = 280/338 (82%), Gaps = 2/338 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           ++LAVI GDGIGPEV+AEA+ VL  V+P  E T YDLGA R+HATGELL +  + ELR +
Sbjct: 1   MRLAVIPGDGIGPEVVAEALKVLGEVVPDTEITRYDLGAARWHATGELLPESVLGELRQH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGA+GDPSVPSG+LERG+LL+LRF LDHHVNLRP RLYPGV  P+     ID VVV
Sbjct: 61  DAILLGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPARLYPGVKSPVSDPGEIDMVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDR-RKHLTLVHKT 183
           REGTEGPY GNGG LR  T HE+ATEVS+NTAFGVERVVRDAFARA  R RKHLTLVHKT
Sbjct: 121 REGTEGPYAGNGGLLRKDTTHEIATEVSINTAFGVERVVRDAFARAASRPRKHLTLVHKT 180

Query: 184 NVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITD 243
           NVL  AGSLWSR V+ V+ ++PDV VAYQH+DA TIHMVTDP RFDVIVTDNLFGDIITD
Sbjct: 181 NVLTHAGSLWSRVVEEVSLQHPDVTVAYQHVDATTIHMVTDPSRFDVIVTDNLFGDIITD 240

Query: 244 LAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVG 303
           LA A+ GGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQG ADPTAAV+SV LLL HVG
Sbjct: 241 LAGAITGGIGLAASGNIDATRRNPSMFEPVHGSAPDIAGQGTADPTAAVLSVALLLDHVG 300

Query: 304 QTEAAARVDKAVSEHLATRGDEKL-STSAVGERIRSLL 340
           Q+EAA RV+ AV+  LATR      +T A+G+R+ +L+
Sbjct: 301 QSEAARRVEAAVAFDLATRDHSAPGATFAIGDRLAALV 338


>tr|C6WG57|C6WG57_ACTMD Tax_Id=446462 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Actinosynnema mirum]
          Length = 345

 Score =  484 bits (1245), Expect = e-135
 Identities = 241/338 (71%), Positives = 284/338 (84%), Gaps = 2/338 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           ++LAVI GDGIGPEV+AEA+ VL  V+P  E T YDLGA R+HATGELL +  + ELR +
Sbjct: 1   MRLAVIPGDGIGPEVVAEALKVLGEVVPAAEITRYDLGAARWHATGELLPESVLGELRQH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGA+GDPSVPSG+LERG+LL+LRF LDHHVNLRP RLYPGV  P+   P ID VVV
Sbjct: 61  DAILLGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPARLYPGVRSPIADPPEIDMVVV 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDR-RKHLTLVHKT 183
           REGTEG Y GNGG LR  TPHE+ATEVS+NT+FGVERVVRDAFARA +R RKHLTLVHKT
Sbjct: 121 REGTEGLYAGNGGLLRKDTPHEIATEVSINTSFGVERVVRDAFARAANRPRKHLTLVHKT 180

Query: 184 NVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITD 243
           NVL  AGSLWSR V+ V+ ++PDV VAYQH+DAATIH+VTDPGR+DVIVTDNLFGDI+TD
Sbjct: 181 NVLTHAGSLWSRVVEEVSLQHPDVTVAYQHVDAATIHLVTDPGRYDVIVTDNLFGDILTD 240

Query: 244 LAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVG 303
           LAAAV GGIGLAASGN+D TR NPSMFEPVHGSAPDIAGQG+ADPTAAV+SV L+L H+G
Sbjct: 241 LAAAVTGGIGLAASGNLDVTRRNPSMFEPVHGSAPDIAGQGVADPTAAVLSVALMLDHLG 300

Query: 304 QTEAAARVDKAVSEHLATRGDEKL-STSAVGERIRSLL 340
           + E+A R++ +V+  LATR      +T A+G+R+ +L+
Sbjct: 301 EHESARRIEASVAFDLATRDHASPGATYAIGDRLAALV 338


>sp|C0ZXM4|LEU3_RHOE4 Tax_Id=234621 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Rhodococcus erythropolis]
          Length = 337

 Score =  475 bits (1222), Expect = e-132
 Identities = 236/337 (70%), Positives = 280/337 (83%), Gaps = 1/337 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIG EV AEA+ VL  ++P +E TEYDLGARRY+ATGELL  + ++++R +
Sbjct: 1   MKLAVIPGDGIGVEVTAEALKVLGKLVPDLETTEYDLGARRYNATGELLPADELDQIRQH 60

Query: 65  DAILLGAIGDPSVPS-GVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVV 123
           DAILLGAIGDP + + G+LERG+LL +RF LDHHVNLRP +LYPG   PL   P IDFVV
Sbjct: 61  DAILLGAIGDPRIVAPGILERGLLLNMRFQLDHHVNLRPAQLYPGALSPLAAQPEIDFVV 120

Query: 124 VREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKT 183
           VREGTEGPYTGNGGA+RVGT HE+ATEVS+NT FG ERVVR AFA AQ R KHLTL+HKT
Sbjct: 121 VREGTEGPYTGNGGAIRVGTDHEIATEVSINTWFGAERVVRYAFALAQTRSKHLTLIHKT 180

Query: 184 NVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITD 243
           NVL+ AG++W+R ++ V  EYPDVE AY HIDAATI+MVTDP RFDVIVTDNLFGDIITD
Sbjct: 181 NVLSNAGAIWTRAIETVGAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDIITD 240

Query: 244 LAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVG 303
           LA AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAG+GIADPTAA++S  LLL H+G
Sbjct: 241 LAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGKGIADPTAAILSAALLLRHLG 300

Query: 304 QTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           + + AARV+  V+  LATRG+  +ST+ +G+RI + L
Sbjct: 301 REDDAARVEAVVAADLATRGEGPISTTEIGDRITAAL 337


>tr|C8XEL3|C8XEL3_NAKMY Tax_Id=479431 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Nakamurella multipartita]
          Length = 340

 Score =  474 bits (1219), Expect = e-132
 Identities = 239/337 (70%), Positives = 275/337 (81%), Gaps = 2/337 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIGPEV+AE + VL  V+P VE  EYDLGA R+H TGELL D  + ELR +
Sbjct: 1   MKLAVIPGDGIGPEVVAEGLKVLRGVVPDVETNEYDLGAARWHRTGELLPDSVLRELREH 60

Query: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
           DAILLGA+GDP+VPSG+LERG+LL+LRF LDHHVNLRP RLYPGV GPL G+  ID VV+
Sbjct: 61  DAILLGAVGDPTVPSGILERGLLLRLRFELDHHVNLRPARLYPGVPGPLAGDKAIDLVVL 120

Query: 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDR-RKHLTLVHKT 183
           REGTEGPY GNGG LR  TPHE+ATEVS+NT FGVERVVRDAF RA  R R+HLTLVHKT
Sbjct: 121 REGTEGPYVGNGGILRKDTPHEIATEVSLNTYFGVERVVRDAFERAARRPRRHLTLVHKT 180

Query: 184 NVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITD 243
           NVL  +G LWSR V+ V+ EY DV VAY H+DAA I++VTDPGRFDV+VTDNLFGDI TD
Sbjct: 181 NVLVHSGQLWSRVVEEVSMEYQDVAVAYCHMDAAMIYLVTDPGRFDVVVTDNLFGDIFTD 240

Query: 244 LAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVG 303
           LAAAV GGIGLAASGN+D +RTNPSMFEPVHGSAPDIAG G ADPTA V+SV LLL H+G
Sbjct: 241 LAAAVSGGIGLAASGNLDVSRTNPSMFEPVHGSAPDIAGTGTADPTATVLSVALLLDHLG 300

Query: 304 QTEAAARVDKAVSEHLATRGDEKLS-TSAVGERIRSL 339
             EAA RV+ AV+  LATR    +  T+A+G+R+ +L
Sbjct: 301 LPEAARRVEAAVAFDLATRQSGSVGRTTAIGDRLAAL 337


>tr|C3JSJ7|C3JSJ7_RHOER Tax_Id=596309 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Rhodococcus erythropolis SK121]
          Length = 337

 Score =  473 bits (1218), Expect = e-131
 Identities = 235/337 (69%), Positives = 280/337 (83%), Gaps = 1/337 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIG EV AEA+ VL  ++P +E TEYDLGARRY+ATGELL  + ++++R +
Sbjct: 1   MKLAVIPGDGIGVEVTAEALKVLGKLVPDLETTEYDLGARRYNATGELLPADELDQIRQH 60

Query: 65  DAILLGAIGDPSVPS-GVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVV 123
           DAILLGAIGDP + + G+LERG+LL +RF LDHHVNLRP +LYPG   PL   P IDFVV
Sbjct: 61  DAILLGAIGDPRIVAPGILERGLLLNMRFQLDHHVNLRPAQLYPGALSPLAAQPEIDFVV 120

Query: 124 VREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKT 183
           VREGTEGPYTGNGGA+RVGT HE+ATEVS+NT FG ERVVR AFA AQ R KHLTL+HKT
Sbjct: 121 VREGTEGPYTGNGGAIRVGTDHEIATEVSINTWFGAERVVRYAFALAQTRSKHLTLIHKT 180

Query: 184 NVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITD 243
           NVL+ AG++W+R ++ V  E+PDVE AY HIDAATI+MVTDP RFDVIVTDNLFGDIITD
Sbjct: 181 NVLSNAGAIWTRAIETVGAEFPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDIITD 240

Query: 244 LAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVG 303
           LA AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAG+GIADPTAA++S  LLL H+G
Sbjct: 241 LAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGKGIADPTAAILSAALLLRHLG 300

Query: 304 QTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           + + AARV+  V+  LATRG+  +ST+ +G+RI + L
Sbjct: 301 REDDAARVEAVVAADLATRGEGPISTTEIGDRITAAL 337


>tr|A3TR55|A3TR55_9MICO Tax_Id=313589 SubName:
           Full=3-isopropylmalate dehydrogenase;[Janibacter sp.
           HTCC2649]
          Length = 361

 Score =  473 bits (1216), Expect = e-131
 Identities = 243/348 (69%), Positives = 281/348 (80%), Gaps = 9/348 (2%)

Query: 2   SSNLKLAVIAGDGIGPEVIAEAVTVLDAVLPG----VEKTEYDLGARRYHATGELLSDET 57
           S ++ LAVIAGDGIGPEV+ E + VL+AV  G    V  T YDLGA+R++ATGE L +  
Sbjct: 13  SKDINLAVIAGDGIGPEVVTEGLKVLEAVTGGSGTKVTSTAYDLGAKRWNATGETLPESV 72

Query: 58  IEELRGYDAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPL---- 113
           ++ELRG+D ILLGAIGDPSVPSGVLERG+LL LRFALDH VNLRP +L+PGV  PL    
Sbjct: 73  LDELRGHDVILLGAIGDPSVPSGVLERGILLPLRFALDHFVNLRPAKLFPGVESPLAVDR 132

Query: 114 VGNPPIDFVVVREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDR 173
           V    IDFVVVREGTEGPY GNGGALR GTPHE+ATEVSVNT FGVERVVR+AFARAQ R
Sbjct: 133 VAPGGIDFVVVREGTEGPYVGNGGALRTGTPHEIATEVSVNTRFGVERVVREAFARAQAR 192

Query: 174 -RKHLTLVHKTNVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIV 232
            RKHLTLVHK NVL  AG LW RTVD V  E+PDVE+AYQH+DAATI +VTDPGRFDVIV
Sbjct: 193 PRKHLTLVHKHNVLTHAGHLWRRTVDEVGTEFPDVEIAYQHVDAATIFLVTDPGRFDVIV 252

Query: 233 TDNLFGDIITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAV 292
           TDNLFGDIITD+AAA+ GGIGLAASGNI+ T + PSMFEPVHGSAPDIAGQG ADPTA +
Sbjct: 253 TDNLFGDIITDIAAAIAGGIGLAASGNINPTGSAPSMFEPVHGSAPDIAGQGKADPTATI 312

Query: 293 MSVGLLLSHVGQTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
           +SV +LL H+G+T+ A RV+ AV+  L  RG E  +TSA+G+ + + L
Sbjct: 313 LSVAMLLEHLGRTDEAGRVEAAVAADLGARGREVRTTSAIGDAVTARL 360


>tr|C5V883|C5V883_9CORY Tax_Id=553207 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Corynebacterium matruchotii ATCC 14266]
          Length = 339

 Score =  472 bits (1214), Expect = e-131
 Identities = 241/333 (72%), Positives = 270/333 (81%), Gaps = 1/333 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           ++LAVI GDGIGPEV AEA+ VL A    ++ T+YDLGARRY ATGELL+D+ +  L+ +
Sbjct: 1   MRLAVIGGDGIGPEVTAEALKVLRACRDDIDTTDYDLGARRYLATGELLTDDDLRSLKEH 60

Query: 65  DAILLGAIGDPS-VPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVV 123
           DAILLGAIG P  VP GVLERG+LL +RFALDHHVNLRP +LYP  T PL     IDFVV
Sbjct: 61  DAILLGAIGAPGEVPPGVLERGLLLTMRFALDHHVNLRPAKLYPTATSPLANPGDIDFVV 120

Query: 124 VREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKT 183
           VREGTEG Y GNGG+LR  TPHEVA+EVS NT FGVERVVRDAF RAQ RRKHLTLVHKT
Sbjct: 121 VREGTEGLYCGNGGSLRKNTPHEVASEVSQNTRFGVERVVRDAFERAQHRRKHLTLVHKT 180

Query: 184 NVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITD 243
           NVL  AG LW RTVD VAQEYPDV V Y HIDAATI+MVTDP R+DVIVTDNLFGDI+TD
Sbjct: 181 NVLVHAGGLWQRTVDEVAQEYPDVTVDYNHIDAATIYMVTDPARYDVIVTDNLFGDILTD 240

Query: 244 LAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVG 303
           LA AV GGIGLAASGNIDAT  NPSMFEPVHGSAPDIAGQGIADPTAA++S  +LL H+ 
Sbjct: 241 LAGAVTGGIGLAASGNIDATGVNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLRHLR 300

Query: 304 QTEAAARVDKAVSEHLATRGDEKLSTSAVGERI 336
             E AAR++ AV+  +A RGDE + T AVG+RI
Sbjct: 301 DEENAARIEAAVAADVAARGDEPIRTVAVGDRI 333


>tr|C2CMU7|C2CMU7_CORST Tax_Id=525268 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Corynebacterium striatum ATCC 6940]
          Length = 338

 Score =  471 bits (1211), Expect = e-131
 Identities = 236/337 (70%), Positives = 274/337 (81%), Gaps = 1/337 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           +KLAVI GDGIGPEV AEA+ VL+AV   +E TEYDLGARRY   GELL+D  +  +R +
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLNAVRDDIETTEYDLGARRYLRNGELLTDADLASIREH 60

Query: 65  DAILLGAIGDPS-VPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVV 123
           DAILLGAIG+P  VP G+LERG+LLK+RFALDHHVNLRP +LYP  T PL     IDFVV
Sbjct: 61  DAILLGAIGEPGQVPPGILERGLLLKMRFALDHHVNLRPSKLYPTATSPLANPGEIDFVV 120

Query: 124 VREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKT 183
           VREGTEG Y GNGG LR GTPHEVA+EVS NT FGVERVVRDAF RA  RRKH+TLVHKT
Sbjct: 121 VREGTEGLYCGNGGTLREGTPHEVASEVSQNTRFGVERVVRDAFERAMGRRKHVTLVHKT 180

Query: 184 NVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITD 243
           NVL  AG LW RTV+ VA+EYP+V V Y HIDAATI+MVTDPGR+DVIVTDNLFGDI+TD
Sbjct: 181 NVLVNAGGLWQRTVEEVAKEYPEVTVDYNHIDAATIYMVTDPGRYDVIVTDNLFGDILTD 240

Query: 244 LAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVG 303
           LA AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAG+GIADPTAA++S  +LL H+G
Sbjct: 241 LAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGKGIADPTAAILSAAMLLRHIG 300

Query: 304 QTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
               A R+++AV+  ++ RG E+L T+ +G+RI + L
Sbjct: 301 DETNAVRIEEAVAADVSARGSEQLGTTEIGDRIAAAL 337


>tr|C0E6S4|C0E6S4_9CORY Tax_Id=566549 SubName: Full=Putative
           uncharacterized protein;[Corynebacterium matruchotii
           ATCC 33806]
          Length = 339

 Score =  470 bits (1209), Expect = e-130
 Identities = 240/333 (72%), Positives = 270/333 (81%), Gaps = 1/333 (0%)

Query: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
           ++LAVI GDGIGPEV AEA+ VL A    ++ T+YDLGARRY ATGELL+D+ +  L+ +
Sbjct: 1   MRLAVIGGDGIGPEVTAEALKVLRACRDDIDTTDYDLGARRYLATGELLTDDDLRSLKEH 60

Query: 65  DAILLGAIGDPS-VPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVV 123
           DAILLGAIG P  VP GVLERG+LL +RFALDHHVNLRP +LYP  T PL     IDFVV
Sbjct: 61  DAILLGAIGAPGEVPPGVLERGLLLTMRFALDHHVNLRPAKLYPTATSPLANPGDIDFVV 120

Query: 124 VREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKT 183
           VREGTEG Y GNGG+LR  TPHEVA+EVS NT FGVERVVRDAF RAQ RRKHLTLVHKT
Sbjct: 121 VREGTEGLYCGNGGSLRKNTPHEVASEVSQNTRFGVERVVRDAFERAQHRRKHLTLVHKT 180

Query: 184 NVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITD 243
           NVL  AG LW RTVD VAQEYPDV V Y HIDAATI+MVTDP R+DVIVTDNLFGDI+TD
Sbjct: 181 NVLVHAGGLWQRTVDEVAQEYPDVTVDYNHIDAATIYMVTDPARYDVIVTDNLFGDILTD 240

Query: 244 LAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVG 303
           LA AV GGIGLAASGNIDAT  NPSMFEPVHGSAPDIAG+GIADPTAA++S  +LL H+ 
Sbjct: 241 LAGAVTGGIGLAASGNIDATGVNPSMFEPVHGSAPDIAGRGIADPTAAILSAAMLLRHLR 300

Query: 304 QTEAAARVDKAVSEHLATRGDEKLSTSAVGERI 336
             E AAR++ AV+  +A RGDE + T AVG+RI
Sbjct: 301 DEENAARIEAAVAADVAARGDEPVRTVAVGDRI 333


>tr|C7MXE6|C7MXE6_SACVD Tax_Id=471857 SubName:
           Full=3-isopropylmalate dehydrogenase;[Saccharomonospora
           viridis]
          Length = 342

 Score =  469 bits (1206), Expect = e-130
 Identities = 236/334 (70%), Positives = 273/334 (81%), Gaps = 2/334 (0%)

Query: 9   VIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGYDAIL 68
           +I GDGIGPEV+ EA+ VL  V+P  E T+YDLGA R+HATGELL +  + ELR +DAIL
Sbjct: 1   MIPGDGIGPEVVTEALKVLTEVVPNAEITKYDLGASRWHATGELLPESVLNELRQHDAIL 60

Query: 69  LGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVVREGT 128
           LGA+GDPSVPSG+LERG+LL+LRF LDHHVNLRPGRLYPGV  PL     +D VVVREGT
Sbjct: 61  LGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPGRLYPGVRSPLAAPGEVDMVVVREGT 120

Query: 129 EGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDR-RKHLTLVHKTNVLA 187
           EGPY GNGG LR  T  E+ATEVSVNTAFG+ RVV DAFARA+ R RKHLTLVHKTNVL 
Sbjct: 121 EGPYAGNGGLLRKDTEQEIATEVSVNTAFGIRRVVADAFARAERRPRKHLTLVHKTNVLE 180

Query: 188 FAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDLAAA 247
            AGSLWSR V+  + ++PDV VAY H+DAATIH+VTDPGRFDVIVTDNLFGDIITDL AA
Sbjct: 181 HAGSLWSRIVEEESLKHPDVTVAYSHVDAATIHLVTDPGRFDVIVTDNLFGDIITDLVAA 240

Query: 248 VCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQTEA 307
           V GGIGLAASGN+D TR NPSMFEPVHGSAPDIAGQ +ADPTAAV+SV LLL H+G+ EA
Sbjct: 241 VTGGIGLAASGNLDITRRNPSMFEPVHGSAPDIAGQNLADPTAAVLSVALLLDHLGEKEA 300

Query: 308 AARVDKAVSEHLATRGDEKL-STSAVGERIRSLL 340
           A R++ +V+  LATR      ST A+G+R+ +L+
Sbjct: 301 ARRIEASVAFDLATRDQNSPGSTQAIGDRLAALV 334


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.317    0.136    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 2,849,484,323
Number of extensions: 126254582
Number of successful extensions: 356968
Number of sequences better than 10.0: 4953
Number of HSP's gapped: 344856
Number of HSP's successfully gapped: 5190
Length of query: 340
Length of database: 4,236,830,644
Length adjustment: 138
Effective length of query: 202
Effective length of database: 2,510,745,412
Effective search space: 507170573224
Effective search space used: 507170573224
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 81 (35.8 bits)