BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_2588
         (496 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|A0QVI7|COBQ_MYCS2 Tax_Id=246196 (cobQ)RecName: Full=Cobyric a...   853   0.0  
sp|Q1BAC5|COBQ_MYCSS Tax_Id=164756 (cobQ)RecName: Full=Cobyric a...   667   0.0  
sp|A1UEN7|COBQ_MYCSK Tax_Id=189918 (cobQ)RecName: Full=Cobyric a...   667   0.0  
sp|A3PY44|COBQ_MYCSJ Tax_Id=164757 (cobQ)RecName: Full=Cobyric a...   667   0.0  
tr|D5PJ95|D5PJ95_9MYCO Tax_Id=525368 (cobQ2)SubName: Full=Cobyri...   624   e-176
sp|Q73VS8|COBQ_MYCPA Tax_Id=1770 (cobQ)RecName: Full=Cobyric aci...   609   e-172
tr|A0QJ08|A0QJ08_MYCA1 Tax_Id=243243 (cobQ)SubName: Full=Cobyric...   607   e-171
tr|B1MDB9|B1MDB9_MYCA9 Tax_Id=561007 (cobQ)RecName: Full=Cobyric...   565   e-159
tr|D5PMX9|D5PMX9_COREQ Tax_Id=525370 (cobQ)SubName: Full=Cobyric...   561   e-158
sp|Q0S258|COBQ_RHOSR Tax_Id=101510 (cobQ)RecName: Full=Cobyric a...   554   e-155
sp|C1B2W9|COBQ_RHOOB Tax_Id=632772 (cobQ)RecName: Full=Cobyric a...   550   e-154
sp|Q5YSA4|COBQ_NOCFA Tax_Id=37329 (cobQ)RecName: Full=Cobyric ac...   544   e-152
tr|C3JM17|C3JM17_RHOER Tax_Id=596309 (cobQ)RecName: Full=Cobyric...   536   e-150
tr|C6WER7|C6WER7_ACTMD Tax_Id=446462 (cobQ)RecName: Full=Cobyric...   536   e-150
tr|C0ZY63|C0ZY63_RHOE4 Tax_Id=234621 (cobQ)RecName: Full=Cobyric...   533   e-149
tr|D0LBG3|D0LBG3_GORB4 Tax_Id=526226 (cobQ)RecName: Full=Cobyric...   506   e-141
sp|A4FM88|COBQ_SACEN Tax_Id=405948 (cobQ)RecName: Full=Cobyric a...   497   e-138
tr|D3Q7E9|D3Q7E9_STANL Tax_Id=446470 (cobQ)RecName: Full=Cobyric...   493   e-137
sp|Q6NGL6|COBQ_CORDI Tax_Id=1717 (cobQ)RecName: Full=Cobyric aci...   479   e-133
tr|C5VCT1|C5VCT1_9CORY Tax_Id=553207 (cobQ)RecName: Full=Cobyric...   479   e-133
tr|D1A9H5|D1A9H5_THECD Tax_Id=471852 (cobQ)RecName: Full=Cobyric...   474   e-131
tr|A4XAN6|A4XAN6_SALTO Tax_Id=369723 (cobQ)RecName: Full=Cobyric...   469   e-130
tr|A8M1Q8|A8M1Q8_SALAI Tax_Id=391037 SubName: Full=Cobyric acid ...   468   e-129
tr|C4RPI9|C4RPI9_9ACTO Tax_Id=219305 (cobQ)RecName: Full=Cobyric...   468   e-129
tr|D3C373|D3C373_9ACTO Tax_Id=648999 (cobQ)RecName: Full=Cobyric...   467   e-129
tr|D1S4Z9|D1S4Z9_9ACTO Tax_Id=644283 (cobQ)RecName: Full=Cobyric...   467   e-129
tr|D5UM31|D5UM31_TSUPA Tax_Id=521096 SubName: Full=Cobyric acid ...   464   e-128
tr|D2BE39|D2BE39_STRRD Tax_Id=479432 (cobQ)RecName: Full=Cobyric...   462   e-128
tr|C2GKW2|C2GKW2_9CORY Tax_Id=548478 (cobQ)RecName: Full=Cobyric...   457   e-126
tr|C0VVE1|C0VVE1_9CORY Tax_Id=548477 (cobQ)RecName: Full=Cobyric...   456   e-126
tr|D2S739|D2S739_GEOOG Tax_Id=526225 SubName: Full=Cobyric acid ...   438   e-121
tr|Q0RLS3|Q0RLS3_FRAAA Tax_Id=326424 (bioD)SubName: Full=Dethiob...   437   e-120
tr|D6M2X5|D6M2X5_9ACTO Tax_Id=465543 SubName: Full=Cobyric acid ...   437   e-120
tr|A8LG25|A8LG25_FRASN Tax_Id=298653 (cobQ)RecName: Full=Cobyric...   436   e-120
tr|C9NHQ4|C9NHQ4_9ACTO Tax_Id=591167 (cobQ)RecName: Full=Cobyric...   436   e-120
tr|D3M1F1|D3M1F1_9ACTO Tax_Id=656024 (cobQ)RecName: Full=Cobyric...   435   e-120
tr|D3CYU2|D3CYU2_9ACTO Tax_Id=102897 SubName: Full=Cobyric acid ...   434   e-119
sp|Q8FP85|COBQ_COREF Tax_Id=152794 (cobQ)RecName: Full=Cobyric a...   432   e-119
tr|C8NPL1|C8NPL1_COREF Tax_Id=196164 (cobQ)SubName: Full=Adenosy...   432   e-119
tr|D6ELH2|D6ELH2_STRLI Tax_Id=457428 SubName: Full=Cobyric acid ...   431   e-119
tr|D1VGL0|D1VGL0_9ACTO Tax_Id=298654 (cobQ)RecName: Full=Cobyric...   430   e-118
sp|Q9RJ20|COBQ_STRCO Tax_Id=1902 (cobQ)RecName: Full=Cobyric aci...   430   e-118
tr|D6K9W1|D6K9W1_9ACTO Tax_Id=645465 SubName: Full=Cobyric acid ...   427   e-117
tr|B1W1S6|B1W1S6_STRGG Tax_Id=455632 SubName: Full=Putative coby...   426   e-117
tr|D1XFS0|D1XFS0_9ACTO Tax_Id=647653 SubName: Full=Cobyric acid ...   425   e-117

>sp|A0QVI7|COBQ_MYCS2 Tax_Id=246196 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium smegmatis]
          Length = 496

 Score =  853 bits (2205), Expect = 0.0
 Identities = 438/496 (88%), Positives = 438/496 (88%)

Query: 1   MTGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXX 60
           MTGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEI    
Sbjct: 1   MTGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIGRAQ 60

Query: 61  XXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADEL 120
                     PSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADEL
Sbjct: 61  AMQARAAGLAPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADEL 120

Query: 121 SSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTV 180
           SSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTV
Sbjct: 121 SSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTV 180

Query: 181 AVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVS 240
           AVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVS
Sbjct: 181 AVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVS 240

Query: 241 VRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
           VRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL
Sbjct: 241 VRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           VVIPGSKATVTDLRWLRE                    CGGFQMLCSRIDDPVESREGRV
Sbjct: 301 VVIPGSKATVTDLRWLRERGLAAGIAAHAAAGRAVLGVCGGFQMLCSRIDDPVESREGRV 360

Query: 361 DGLGLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGTHWHG 420
           DGLGLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGTHWHG
Sbjct: 361 DGLGLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGTHWHG 420

Query: 421 LLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILDLL 480
           LLDNDALRRDWLTE                        QLDLMADLIENHLDVGAILDLL
Sbjct: 421 LLDNDALRRDWLTEVAAAAGRDGFVVADDVDVSARRDAQLDLMADLIENHLDVGAILDLL 480

Query: 481 EHGAPHRPTMSTALHV 496
           EHGAPHRPTMSTALHV
Sbjct: 481 EHGAPHRPTMSTALHV 496


>sp|Q1BAC5|COBQ_MYCSS Tax_Id=164756 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium sp.]
          Length = 495

 Score =  667 bits (1722), Expect = 0.0
 Identities = 339/494 (68%), Positives = 375/494 (75%)

Query: 1   MTGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXX 60
           MTGGALLVAGTTSDAGKSM+V GLCRLL RKG+ VAPFKAQNMSNNSAVTV+GGEI    
Sbjct: 1   MTGGALLVAGTTSDAGKSMVVAGLCRLLARKGVRVAPFKAQNMSNNSAVTVDGGEIGRAQ 60

Query: 61  XXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADEL 120
                     PSVRFNP+LLKPG DRTSQLVVRG+VTG+V+A DYI HRD LA VVADEL
Sbjct: 61  AMQARAAGLDPSVRFNPVLLKPGSDRTSQLVVRGRVTGTVSATDYITHRDRLADVVADEL 120

Query: 121 SSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTV 180
           +SLR +FD V+CEGAGSPAEINLR TDLANMGLAR A LPVIVVGDIDRGG+LAHL GTV
Sbjct: 121 ASLRAEFDVVLCEGAGSPAEINLRRTDLANMGLARRAHLPVIVVGDIDRGGVLAHLFGTV 180

Query: 181 AVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVS 240
           AVL P DQAL++GFVVNKFRGDP+LLAPGL QL +LTGRPTYGVIP+ DE+W+DTEDSVS
Sbjct: 181 AVLHPDDQALIAGFVVNKFRGDPTLLAPGLDQLHDLTGRPTYGVIPYSDELWMDTEDSVS 240

Query: 241 VRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
           V  G  +G P PPRG   L VAA+RLPRISNSTDIEALACEPGV VRWVTD AD+  AD+
Sbjct: 241 VVAGRTIGRPTPPRGADGLRVAAVRLPRISNSTDIEALACEPGVTVRWVTDPADVADADV 300

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           VV+PG+KATV DL+WLR                     CGGFQMLC  IDD VESR GRV
Sbjct: 301 VVLPGTKATVADLQWLRTAGLAEPIAAHAGAGRPLLGICGGFQMLCRHIDDAVESRAGRV 360

Query: 361 DGLGLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGTHWHG 420
           DGLGLLDADI FAA+KTLRH  TPL GYEIHHGQV R A  DW GIG+RR AVYGTHWHG
Sbjct: 361 DGLGLLDADIAFAAEKTLRHRTTPLQGYEIHHGQVTRCAADDWAGIGVRRDAVYGTHWHG 420

Query: 421 LLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILDLL 480
           L DND  RR WL +                        QLD+MADL++NHLD+ A L L+
Sbjct: 421 LFDNDGFRRAWLADAAAAAGRSGFVVADDIDVSARRDAQLDVMADLLQNHLDLDAALGLV 480

Query: 481 EHGAPHRPTMSTAL 494
           + G P RPT+ST +
Sbjct: 481 DAGPPPRPTISTGI 494


>sp|A1UEN7|COBQ_MYCSK Tax_Id=189918 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium sp.]
          Length = 495

 Score =  667 bits (1722), Expect = 0.0
 Identities = 339/494 (68%), Positives = 375/494 (75%)

Query: 1   MTGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXX 60
           MTGGALLVAGTTSDAGKSM+V GLCRLL RKG+ VAPFKAQNMSNNSAVTV+GGEI    
Sbjct: 1   MTGGALLVAGTTSDAGKSMVVAGLCRLLARKGVRVAPFKAQNMSNNSAVTVDGGEIGRAQ 60

Query: 61  XXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADEL 120
                     PSVRFNP+LLKPG DRTSQLVVRG+VTG+V+A DYI HRD LA VVADEL
Sbjct: 61  AMQARAAGLDPSVRFNPVLLKPGSDRTSQLVVRGRVTGTVSATDYITHRDRLADVVADEL 120

Query: 121 SSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTV 180
           +SLR +FD V+CEGAGSPAEINLR TDLANMGLAR A LPVIVVGDIDRGG+LAHL GTV
Sbjct: 121 ASLRAEFDVVLCEGAGSPAEINLRRTDLANMGLARRAHLPVIVVGDIDRGGVLAHLFGTV 180

Query: 181 AVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVS 240
           AVL P DQAL++GFVVNKFRGDP+LLAPGL QL +LTGRPTYGVIP+ DE+W+DTEDSVS
Sbjct: 181 AVLHPDDQALIAGFVVNKFRGDPTLLAPGLDQLHDLTGRPTYGVIPYSDELWMDTEDSVS 240

Query: 241 VRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
           V  G  +G P PPRG   L VAA+RLPRISNSTDIEALACEPGV VRWVTD AD+  AD+
Sbjct: 241 VVAGRTIGRPTPPRGADGLRVAAVRLPRISNSTDIEALACEPGVTVRWVTDPADVADADV 300

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           VV+PG+KATV DL+WLR                     CGGFQMLC  IDD VESR GRV
Sbjct: 301 VVLPGTKATVADLQWLRTAGLAEPIAAHAGAGRPLLGICGGFQMLCRHIDDAVESRAGRV 360

Query: 361 DGLGLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGTHWHG 420
           DGLGLLDADI FAA+KTLRH  TPL GYEIHHGQV R A  DW GIG+RR AVYGTHWHG
Sbjct: 361 DGLGLLDADIAFAAEKTLRHRTTPLQGYEIHHGQVTRCAADDWAGIGVRRDAVYGTHWHG 420

Query: 421 LLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILDLL 480
           L DND  RR WL +                        QLD+MADL++NHLD+ A L L+
Sbjct: 421 LFDNDGFRRAWLADAAAAAGRSGFVVADDIDVSARRDAQLDVMADLLQNHLDLDAALGLV 480

Query: 481 EHGAPHRPTMSTAL 494
           + G P RPT+ST +
Sbjct: 481 DAGPPPRPTISTGI 494


>sp|A3PY44|COBQ_MYCSJ Tax_Id=164757 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium sp.]
          Length = 495

 Score =  667 bits (1722), Expect = 0.0
 Identities = 339/494 (68%), Positives = 375/494 (75%)

Query: 1   MTGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXX 60
           MTGGALLVAGTTSDAGKSM+V GLCRLL RKG+ VAPFKAQNMSNNSAVTV+GGEI    
Sbjct: 1   MTGGALLVAGTTSDAGKSMVVAGLCRLLARKGVRVAPFKAQNMSNNSAVTVDGGEIGRAQ 60

Query: 61  XXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADEL 120
                     PSVRFNP+LLKPG DRTSQLVVRG+VTG+V+A DYI HRD LA VVADEL
Sbjct: 61  AMQARAAGLDPSVRFNPVLLKPGSDRTSQLVVRGRVTGTVSATDYITHRDRLADVVADEL 120

Query: 121 SSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTV 180
           +SLR +FD V+CEGAGSPAEINLR TDLANMGLAR A LPVIVVGDIDRGG+LAHL GTV
Sbjct: 121 ASLRAEFDVVLCEGAGSPAEINLRRTDLANMGLARRAHLPVIVVGDIDRGGVLAHLFGTV 180

Query: 181 AVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVS 240
           AVL P DQAL++GFVVNKFRGDP+LLAPGL QL +LTGRPTYGVIP+ DE+W+DTEDSVS
Sbjct: 181 AVLHPDDQALIAGFVVNKFRGDPTLLAPGLDQLHDLTGRPTYGVIPYSDELWMDTEDSVS 240

Query: 241 VRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
           V  G  +G P PPRG   L VAA+RLPRISNSTDIEALACEPGV VRWVTD AD+  AD+
Sbjct: 241 VVAGRTIGRPTPPRGADGLRVAAVRLPRISNSTDIEALACEPGVTVRWVTDPADVADADV 300

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           VV+PG+KATV DL+WLR                     CGGFQMLC  IDD VESR GRV
Sbjct: 301 VVLPGTKATVADLQWLRTAGLAEPIAAHAGAGRPLLGICGGFQMLCRHIDDAVESRAGRV 360

Query: 361 DGLGLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGTHWHG 420
           DGLGLLDADI FAA+KTLRH  TPL GYEIHHGQV R A  DW GIG+RR AVYGTHWHG
Sbjct: 361 DGLGLLDADIAFAAEKTLRHRTTPLQGYEIHHGQVTRCAADDWAGIGVRRDAVYGTHWHG 420

Query: 421 LLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILDLL 480
           L DND  RR WL +                        QLD+MADL++NHLD+ A L L+
Sbjct: 421 LFDNDGFRRAWLADAAAAAGRSGFVVADDIDVSARRDAQLDVMADLLQNHLDLDAALGLV 480

Query: 481 EHGAPHRPTMSTAL 494
           + G P RPT+ST +
Sbjct: 481 DAGPPPRPTISTGI 494


>tr|D5PJ95|D5PJ95_9MYCO Tax_Id=525368 (cobQ2)SubName: Full=Cobyric
           acid synthase CobQ; EC=6.3.5.10;[Mycobacterium
           parascrofulaceum ATCC BAA-614]
          Length = 504

 Score =  624 bits (1609), Expect = e-176
 Identities = 321/500 (64%), Positives = 362/500 (72%), Gaps = 9/500 (1%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGT+SDAGKS++V GLCRLL R+G+ VAPFKAQNMSNNS VTVEGGEI       
Sbjct: 3   GALLVAGTSSDAGKSVVVAGLCRLLARRGVRVAPFKAQNMSNNSVVTVEGGEIGRAQALQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNPILLKPG DRTSQLV+RGQ+  SV AA Y+ HR+ LA +VADELSSL
Sbjct: 63  ARAAGLEPSVRFNPILLKPGSDRTSQLVIRGQIAESVTAASYVRHRERLAGIVADELSSL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R +FD VICEGAGSPAEINLRATDLANMGLAR+A LPVI+VGDIDRGGLLAHL GTVAVL
Sbjct: 123 RGEFDVVICEGAGSPAEINLRATDLANMGLARSANLPVILVGDIDRGGLLAHLFGTVAVL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           EP DQAL++GFVVNKFRGDP+LL PGLRQL  +T RPTYGV+P+ +E+WLD EDS+SV  
Sbjct: 183 EPEDQALIAGFVVNKFRGDPALLEPGLRQLHAITDRPTYGVLPYAEELWLDAEDSLSVVA 242

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
           G +VGAP PPRG + L VAAIRLPRISNSTD+EALACEPGV+VRW TD ADL   DLVVI
Sbjct: 243 GRVVGAPAPPRGSEWLRVAAIRLPRISNSTDVEALACEPGVMVRWSTDPADLADTDLVVI 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSK+TV DL WLR+                    CGGFQMLC RIDD VES  G V  L
Sbjct: 303 PGSKSTVADLNWLRDRGLAEEITAHAAAGKPVLGICGGFQMLCRRIDDTVESGAGEVAAL 362

Query: 364 GLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGI---------GLRRGAVY 414
           GLLDADI F   K LR W  PL GYEIHHG+V+R AE  W G+         G+R GAV+
Sbjct: 363 GLLDADIVFGETKILRRWPQPLSGYEIHHGRVSRCAEESWFGVEGGRDCQPHGVRHGAVF 422

Query: 415 GTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVG 474
           GTHWHGLLDND  RR WLT                         QLD++ADL+ +HLDV 
Sbjct: 423 GTHWHGLLDNDDFRRAWLTRVAVVAGRAGFVAAADTDVAARRDAQLDVIADLLTSHLDVD 482

Query: 475 AILDLLEHGAPHRPTMSTAL 494
           A+L LL+   P RP ++T L
Sbjct: 483 AVLGLLDGPRPRRPRIATRL 502


>sp|Q73VS8|COBQ_MYCPA Tax_Id=1770 (cobQ)RecName: Full=Cobyric acid
           synthase;[Mycobacterium paratuberculosis]
          Length = 497

 Score =  609 bits (1571), Expect = e-172
 Identities = 319/496 (64%), Positives = 363/496 (73%), Gaps = 8/496 (1%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGT+SDAGKS++V GLCRLL R+G+ VAPFKAQNMSNNSAVTVEGGEI       
Sbjct: 3   GALLVAGTSSDAGKSVVVAGLCRLLARRGVRVAPFKAQNMSNNSAVTVEGGEIGRAQAIQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNPILLKPG DRTSQLV++GQV  SV A  Y+ HRD LAA+V +EL+ L
Sbjct: 63  ARAAGLEPSVRFNPILLKPGSDRTSQLVIKGQVAESVTATSYVQHRDRLAALVLNELTCL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R++FDAVICEGAGSPAEINLRATDLANMGLARAA L VI+VGDIDRGGLLAHL GTVAVL
Sbjct: 123 RDEFDAVICEGAGSPAEINLRATDLANMGLARAADLAVILVGDIDRGGLLAHLFGTVAVL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           +P DQAL++GFVVNKFRGDP+LL PGLR+L ++TGRPTYGV+P+ D +WLD EDS+SV  
Sbjct: 183 DPQDQALIAGFVVNKFRGDPALLQPGLRRLHDITGRPTYGVLPYADRLWLDAEDSLSVLA 242

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
             +VGAP+PP G+  L VAA+RLPRISNSTD+EALACEPGV+VRWV++ +D+  ADLVVI
Sbjct: 243 HRVVGAPDPPLGDDWLRVAAVRLPRISNSTDVEALACEPGVLVRWVSEPSDVADADLVVI 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSKATV DL WLRE                    CGGFQMLC RIDD VES  G V GL
Sbjct: 303 PGSKATVADLSWLRERGLAAAITAHAAAGRPVLGICGGFQMLCRRIDDRVESGAGEVAGL 362

Query: 364 GLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGI-----GLRRGAVYGTHW 418
           GLLDADI F   KTLR W+ PL GYEIHHG+V+R AE  W        GL RGAV+GTHW
Sbjct: 363 GLLDADIAFHPAKTLRRWQRPLAGYEIHHGRVSRCAEHSWFDSDAEPQGLVRGAVFGTHW 422

Query: 419 HGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILD 478
           HGLLDND  RR WL                          QLDL ADL+  HLDV A+L 
Sbjct: 423 HGLLDNDDFRRAWLVR--VADAAGRRFVPGDTDVAARRDAQLDLAADLLAAHLDVDAVLG 480

Query: 479 LLEHGAPHRPTMSTAL 494
           LL+ G P RP ++T L
Sbjct: 481 LLD-GPPPRPRLATRL 495


>tr|A0QJ08|A0QJ08_MYCA1 Tax_Id=243243 (cobQ)SubName: Full=Cobyric
           acid synthase CobQ; EC=6.3.5.10;[Mycobacterium avium]
          Length = 497

 Score =  607 bits (1565), Expect = e-171
 Identities = 317/496 (63%), Positives = 363/496 (73%), Gaps = 8/496 (1%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGT+SDAGKS++V GLCRLL R+G+ VAPFKAQNMSNNSAVTVEGGEI       
Sbjct: 3   GALLVAGTSSDAGKSVVVAGLCRLLARRGVRVAPFKAQNMSNNSAVTVEGGEIGRAQAIQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNP+LLKPG DRTSQLV++GQV  SV A  Y+ HRD LAA+V +EL+ L
Sbjct: 63  ARAAGLEPSVRFNPVLLKPGSDRTSQLVIKGQVAESVTATSYVQHRDRLAALVLNELTCL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R++FDAVICEGAGSPAEINLRATDLANMGLARAA L VI+VGDIDRGGLLAHL GTVAVL
Sbjct: 123 RDEFDAVICEGAGSPAEINLRATDLANMGLARAADLAVILVGDIDRGGLLAHLFGTVAVL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           +P DQAL++GFVVNKFRGDP+LL PGLR+L ++TGRPTYGV+P+ D +WLD EDS+SV  
Sbjct: 183 DPQDQALIAGFVVNKFRGDPALLQPGLRRLHDITGRPTYGVLPYADGLWLDAEDSLSVLA 242

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
             +VGAP+PP G+  L VAA+RLPRISNSTD+EALACEPGV+VRWV++ +D+  ADLVVI
Sbjct: 243 HRVVGAPDPPLGDDWLRVAAVRLPRISNSTDVEALACEPGVLVRWVSEPSDVADADLVVI 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSKATV DL W+RE                    CGGFQMLC RIDD VES  G V GL
Sbjct: 303 PGSKATVADLSWVRERGLADAITAHAAAGRPVLGICGGFQMLCRRIDDRVESGAGEVAGL 362

Query: 364 GLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLGI-----GLRRGAVYGTHW 418
           GLLDADI F   KTLR W+ PL GYEIHHG+V+R AE  W        GL RGAV+GTHW
Sbjct: 363 GLLDADIAFHPTKTLRRWQRPLAGYEIHHGRVSRCAEHSWFDSDAEPQGLVRGAVFGTHW 422

Query: 419 HGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILD 478
           HGLLDND  RR WL                          QLDL ADL+  HLDV A+L 
Sbjct: 423 HGLLDNDDFRRAWLVR--VAEAAGRRFVPGDTDVAARRDAQLDLAADLLAAHLDVDAVLG 480

Query: 479 LLEHGAPHRPTMSTAL 494
           LL+ G P RP ++T L
Sbjct: 481 LLD-GPPPRPRLATRL 495


>tr|B1MDB9|B1MDB9_MYCA9 Tax_Id=561007 (cobQ)RecName: Full=Cobyric
           acid synthase;[Mycobacterium abscessus]
          Length = 507

 Score =  565 bits (1455), Expect = e-159
 Identities = 299/503 (59%), Positives = 346/503 (68%), Gaps = 12/503 (2%)

Query: 1   MTG---GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIX 57
           MTG   GALLV G +SDAGKS++V GLCRLL RKG+ VAPFKAQNMSNNS VTV+GGEI 
Sbjct: 1   MTGAVSGALLVGGVSSDAGKSLVVTGLCRLLARKGIRVAPFKAQNMSNNSVVTVDGGEIG 60

Query: 58  XXXXXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVA 117
                        PSVRFNP+LLKPG DRTSQLVVRG+ TG+V+A  Y+ HR+ L  VVA
Sbjct: 61  RAQALQARACGLEPSVRFNPVLLKPGSDRTSQLVVRGRATGNVSARSYVEHREELRQVVA 120

Query: 118 DELSSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLH 177
           ++L +LRE++D VICEGAGS AEINLR TD+ANMGLARAA LPV++VGDIDRGG+LAHL 
Sbjct: 121 EDLRTLREEYDVVICEGAGSVAEINLRTTDIANMGLARAAGLPVVLVGDIDRGGVLAHLF 180

Query: 178 GTVAVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTED 237
           G+VAVLEPADQ LV+GF+VNKFRGDP+LL PGL QLA LTGRPTYGV+P+ D++WLD ED
Sbjct: 181 GSVAVLEPADQRLVAGFIVNKFRGDPTLLEPGLEQLATLTGRPTYGVLPYDDQLWLDAED 240

Query: 238 SVSVRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTG 297
           SVSV   G VG    P G++ L VAA+RLPRISNSTDIEALACEPGV VRW    AD+  
Sbjct: 241 SVSVVASGQVGQTSDPIGQEWLRVAAVRLPRISNSTDIEALACEPGVTVRWAAHPADIAD 300

Query: 298 ADLVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESRE 357
           AD+VVIPG+KATV DL W+R                     CGGFQML + IDD VES  
Sbjct: 301 ADVVVIPGTKATVADLAWMRRHGVADAVVAHARSGGPVLGICGGFQMLATTIDDRVESGA 360

Query: 358 GRVDGLGLLDADIEFAAQKTLRHWETP-LHGYEIHHGQVARSAETDWL---GIGLRRGAV 413
           G V+GLGLLD DI F   KTLR W  P L GYEIHHG V RSA   WL     G   GAV
Sbjct: 361 GAVEGLGLLDIDIAFEPVKTLRRWGPPGLTGYEIHHGTVTRSAVPPWLTDHDEGAVDGAV 420

Query: 414 YGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDV 473
           +GTHWHG+LDND  RR WLT+                        QLD +ADL+  H+DV
Sbjct: 421 WGTHWHGVLDNDDFRRAWLTQAAAAAGRSGFAVAADTNVGDRRAAQLDRLADLVGTHVDV 480

Query: 474 GAILDLLEH-----GAPHRPTMS 491
            A+  + E       AP  P ++
Sbjct: 481 DALESVWEESGLPASAPSYPVIA 503


>tr|D5PMX9|D5PMX9_COREQ Tax_Id=525370 (cobQ)SubName: Full=Cobyric
           acid synthase CobQ; EC=6.3.5.10;[Rhodococcus equi ATCC
           33707]
          Length = 510

 Score =  561 bits (1446), Expect = e-158
 Identities = 302/499 (60%), Positives = 347/499 (69%), Gaps = 12/499 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGTTSDAGKS+LV GLCR+L R+G+ VAPFKAQNMSNNS VT++GGEI       
Sbjct: 7   GALLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQ 66

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNP+LLKPGGDRTSQLVVRG+   +V A DYI HR+ L  +VADEL+SL
Sbjct: 67  ARACGLEPSVRFNPVLLKPGGDRTSQLVVRGKAVTTVGARDYIEHREWLRDIVADELASL 126

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R++FD VICEGAGSPAEINLRATDLANMGLA+AA LPVIVVGDIDRGG+LAHL GTVAVL
Sbjct: 127 RDEFDVVICEGAGSPAEINLRATDLANMGLAQAAQLPVIVVGDIDRGGVLAHLFGTVAVL 186

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
            P DQAL++GFV+NKFRGD SLLAPGL QL  LTGRPT GVIPF +E+WLD EDS+ V  
Sbjct: 187 SPEDQALIAGFVINKFRGDVSLLAPGLEQLRALTGRPTLGVIPFAEELWLDAEDSLGVVG 246

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
              VG P PP G + L VAAIRLPRISNSTD+EALACEPGV V WV++ + L  ADLVV+
Sbjct: 247 DAPVGRPAPPTGGEWLRVAAIRLPRISNSTDVEALACEPGVSVHWVSEPSRLADADLVVL 306

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSK+TVTDL WLR                     CGG+QML + IDD VES  G VDGL
Sbjct: 307 PGSKSTVTDLEWLRRSGIGDALIRRARAGGAILGICGGYQMLGTVIDDDVESGAGSVDGL 366

Query: 364 GLLDADIEFAAQKTLRHWE-----TPLHGYEIHHGQVARSAETDWLGI------GLRRGA 412
           GLLD +I FA  K L   +      PL GYEIHHG+V R+ +   L        G  RG+
Sbjct: 367 GLLDLEIAFAPDKVLAQVQGDADGIPLRGYEIHHGRVRRNGDAPLLSYADGGKEGSVRGS 426

Query: 413 VYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLD 472
           V GTHWHG+L+ND  RR  LTE                        QLDL+ADL+E HLD
Sbjct: 427 VRGTHWHGILENDEYRRRLLTEVAETAGRAGFAVAPDTDVAQVREAQLDLLADLVEQHLD 486

Query: 473 VGAILDLLEHGAPHR-PTM 490
           V A+L  ++ GA  R PT+
Sbjct: 487 VDAVLATVDGGAAMRLPTI 505


>sp|Q0S258|COBQ_RHOSR Tax_Id=101510 (cobQ)RecName: Full=Cobyric acid
           synthase;[Rhodococcus sp.]
          Length = 512

 Score =  554 bits (1427), Expect = e-155
 Identities = 297/493 (60%), Positives = 339/493 (68%), Gaps = 11/493 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGTTSDAGKS+LV GLCR+L R+G+ VAPFKAQNMSNNS VT++GGEI       
Sbjct: 8   GALLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQ 67

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNP+LLKPG DRTSQLVVRG+   SV A DYI HR HL AVVA+EL+SL
Sbjct: 68  AAACGLEPSVRFNPVLLKPGSDRTSQLVVRGRAVTSVGARDYIEHRQHLRAVVAEELASL 127

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R D+D VICEGAGSPAEINLRATDLANMGLARAA LPVIVVGDIDRGG+LAHL GTVAVL
Sbjct: 128 RADYDVVICEGAGSPAEINLRATDLANMGLARAAGLPVIVVGDIDRGGVLAHLFGTVAVL 187

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
            P DQAL++GFV+NKFRGD SLL PGL QL  +TGRPT GVIPF +++WLD EDS+ V  
Sbjct: 188 GPDDQALIAGFVINKFRGDVSLLGPGLEQLTAVTGRPTLGVIPFAEDLWLDAEDSLGVVG 247

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
              VG P PP G+  L VAAIRLPRISNSTD+EALACEPGV VRW+TD + L   DL+V+
Sbjct: 248 DAPVGRPAPPIGDDWLRVAAIRLPRISNSTDVEALACEPGVSVRWITDPSRLQDTDLIVL 307

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSK+TV+DL WLR                     CGG+QML S I D VES  G V GL
Sbjct: 308 PGSKSTVSDLEWLRRNGIADAIAAHAKRGGPVLGVCGGYQMLGSVIVDDVESGRGAVPGL 367

Query: 364 GLLDADIEFAAQKTLRHWE-----TPLHGYEIHHGQVARSAETDWL------GIGLRRGA 412
           GLLD ++EFA  K L          P+ GYEIHHG+V R+ +   L        G  RGA
Sbjct: 368 GLLDLEVEFAPDKVLAQVRGNAHGVPVSGYEIHHGRVRRNGDQPLLHASSGAAEGSIRGA 427

Query: 413 VYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLD 472
           VYGTHWHGLL+ D  RR  L +                        QLDL+ADL+E +LD
Sbjct: 428 VYGTHWHGLLETDRFRRLLLDDVAEHAGRTGFVTAPDTDVAAIRTAQLDLLADLVEQNLD 487

Query: 473 VGAILDLLEHGAP 485
           + A+ DLL  GAP
Sbjct: 488 LRALEDLLGAGAP 500


>sp|C1B2W9|COBQ_RHOOB Tax_Id=632772 (cobQ)RecName: Full=Cobyric acid
           synthase;[Rhodococcus opacus]
          Length = 512

 Score =  550 bits (1417), Expect = e-154
 Identities = 296/493 (60%), Positives = 338/493 (68%), Gaps = 11/493 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGTTSDAGKS+LV GLCR+L R+G+ VAPFKAQNMSNNS VT++GGEI       
Sbjct: 8   GALLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQ 67

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNP+LLKPG DRTSQLVVRG+   +V A DYI HR HL  VVA+EL SL
Sbjct: 68  AAACGLEPSVRFNPVLLKPGSDRTSQLVVRGRAVTTVGARDYIEHRGHLRTVVAEELQSL 127

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R D+D V+CEGAGSPAEINLRATDLANMGLARAA LPV+VVGDIDRGG+LAHL GTVAVL
Sbjct: 128 RADYDVVLCEGAGSPAEINLRATDLANMGLARAADLPVLVVGDIDRGGVLAHLFGTVAVL 187

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
            P DQAL++GFV+NKFRGD SLLAPGL QL  +TGRPT GVIPF +++WLD EDS+ V  
Sbjct: 188 APEDQALIAGFVINKFRGDVSLLAPGLGQLTAMTGRPTLGVIPFAEDLWLDAEDSLGVVG 247

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
              VG P PP G+  L VAAIRLPRISNSTD+EALACEPGV VRWVTD + L  ADLVV+
Sbjct: 248 DAPVGRPAPPVGDDWLRVAAIRLPRISNSTDVEALACEPGVSVRWVTDPSRLEDADLVVL 307

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSK+TV+DL WLR                     CGG+QML S I D VES  G V GL
Sbjct: 308 PGSKSTVSDLEWLRRNGIADAIAVHAKRGGPVLGVCGGYQMLGSVIVDDVESGRGAVPGL 367

Query: 364 GLLDADIEFAAQKTLRHWE-----TPLHGYEIHHGQVARSAETDWL------GIGLRRGA 412
           GLLD ++EFA  K L          P+ GYEIHHG+V R+ +   L        G  RGA
Sbjct: 368 GLLDLEVEFAPDKVLAQVRGDAHGVPVSGYEIHHGRVRRNGDPPLLHARGGAAEGSIRGA 427

Query: 413 VYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLD 472
           VYGTHWHGLL+ D  RR  L +                        QLDL+ADL+E +LD
Sbjct: 428 VYGTHWHGLLETDRFRRILLDDVAEHAGRTGFVTAPDTDVAAIRTAQLDLLADLVEQNLD 487

Query: 473 VGAILDLLEHGAP 485
           + A+  LL  GAP
Sbjct: 488 LPALQALLGAGAP 500


>sp|Q5YSA4|COBQ_NOCFA Tax_Id=37329 (cobQ)RecName: Full=Cobyric acid
           synthase;[Nocardia farcinica]
          Length = 520

 Score =  544 bits (1402), Expect = e-152
 Identities = 292/507 (57%), Positives = 336/507 (66%), Gaps = 25/507 (4%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGTTSDAGKS++V GLCR+L R+G+ VAPFKAQNMSNNS VT++GGEI       
Sbjct: 3   GALLVAGTTSDAGKSVVVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNP+LLKPG DR SQLVVRGQ   +V AADY  HR  L  VVA EL+SL
Sbjct: 63  ARACGLEPSVRFNPVLLKPGSDRRSQLVVRGQAVDTVGAADYFRHRTALREVVAAELASL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R +FD V+CEGAGSPAEINLRATDLANMGLARAA LPV+VVGDIDRGG+LAHL GTVAVL
Sbjct: 123 RAEFDVVLCEGAGSPAEINLRATDLANMGLARAADLPVLVVGDIDRGGVLAHLFGTVAVL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           EP DQ L++GFVVNKFRGD  LL PGL +LAELTGRPT GV+PF +E+WLD EDS+    
Sbjct: 183 EPDDQRLIAGFVVNKFRGDVDLLRPGLDRLAELTGRPTLGVLPFAEELWLDAEDSLGTVA 242

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
              VG P PP G + LTVAA+RLPRISNSTD+EALACEPGV VRWV++ + L  ADLVV+
Sbjct: 243 DAPVGRPRPPVGTEWLTVAAVRLPRISNSTDVEALACEPGVAVRWVSEPSRLADADLVVV 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSK+TV+DL WLR                     CGG+QML  RI D VES  G V GL
Sbjct: 303 PGSKSTVSDLAWLRRTGLGEALRARVTAGRPVLAICGGYQMLGRRIVDEVESGAGEVAGL 362

Query: 364 GLLDADIEFAAQKTLRHWE-----TPLHGYEIHHGQVARSAETDWLGI------------ 406
           G+ D + EFAA K LR         P+ GYEIHHG+V RS +  WLG+            
Sbjct: 363 GVFDLETEFAAPKVLRRVTGMGAGNPVRGYEIHHGRVRRSGDAPWLGLVDAPEAAVDGGE 422

Query: 407 --------GLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXX 458
                   G   G  +GTH HGLL++D  RR WL E                        
Sbjct: 423 DAVPLTPEGSVTGGAWGTHVHGLLESDGFRRAWLREVAARAGRHGFQVAPDTSVAAVRAG 482

Query: 459 QLDLMADLIENHLDVGAILDLLEHGAP 485
           QLDL+ADL+E HLD  A+  +L  GAP
Sbjct: 483 QLDLLADLVEKHLDQDALERILTDGAP 509


>tr|C3JM17|C3JM17_RHOER Tax_Id=596309 (cobQ)RecName: Full=Cobyric
           acid synthase;[Rhodococcus erythropolis SK121]
          Length = 503

 Score =  536 bits (1382), Expect = e-150
 Identities = 291/503 (57%), Positives = 339/503 (67%), Gaps = 16/503 (3%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGTTSDAGKS+LV GLCR+L R+G+ VAPFKAQNMSNNS VT++GGEI       
Sbjct: 3   GALLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNP+LLKPG DRTSQLVVRG+   +V A DY+ HR  L AVVA++L SL
Sbjct: 63  ARACGLEPSVRFNPVLLKPGSDRTSQLVVRGKAMTTVGARDYMQHRQWLRAVVAEDLESL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R +FD VICEGAGSPAEINLRATDLANMGLA AA +PV+VVGDIDRGG+LAHL GTVAVL
Sbjct: 123 RSEFDVVICEGAGSPAEINLRATDLANMGLAEAARIPVVVVGDIDRGGVLAHLFGTVAVL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
            P+DQAL++GFV+NKFRGD +LL PGL QL  LTGRPT GVIPF D++WLD EDS+ V  
Sbjct: 183 SPSDQALIAGFVINKFRGDVALLEPGLEQLRSLTGRPTLGVIPFADDLWLDAEDSLGVTG 242

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
              VG P PP G   LTVAA+RLPRISNSTD+EALACEPGV V WVTD + +  ADLVVI
Sbjct: 243 NAPVGRPGPPVGSAWLTVAAVRLPRISNSTDVEALACEPGVAVSWVTDPSRIRDADLVVI 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSK+TV+DL WLR                     CGG+QML + I D VES  G   GL
Sbjct: 303 PGSKSTVSDLEWLRSTGLADEIVARAGRGQAVLGICGGYQMLGNSIVDDVESGSGTTAGL 362

Query: 364 GLLDADIEFAAQKTLRHWE-----TPLHGYEIHHGQVARS------AETDWLGIGLRRGA 412
           GLLD D+EFA  K L           + GYEIHHG+V R+      A++  +  G  RG 
Sbjct: 363 GLLDLDVEFAPDKVLAQMTGTADGISVSGYEIHHGRVVRNGDHPLLADSSGMPEGSVRGP 422

Query: 413 VYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLD 472
           V GTHWHGLL++D  RR  L E                        QLDL+ADL+E HLD
Sbjct: 423 VRGTHWHGLLESDDFRRSLLRE----LAVPGFVAAPDTAVAAVREQQLDLLADLVEQHLD 478

Query: 473 VGAILDLLEHGAP-HRPTMSTAL 494
              +  L+  GAP   P +++AL
Sbjct: 479 QDLLEKLINGGAPIGLPVIASAL 501


>tr|C6WER7|C6WER7_ACTMD Tax_Id=446462 (cobQ)RecName: Full=Cobyric
           acid synthase;[Actinosynnema mirum]
          Length = 509

 Score =  536 bits (1381), Expect = e-150
 Identities = 289/497 (58%), Positives = 342/497 (68%), Gaps = 20/497 (4%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GA+LVAGTTSDAGKS+LV GLCR L R+G+ VAPFKAQNMSNNSAVT +GGEI       
Sbjct: 3   GAVLVAGTTSDAGKSVLVAGLCRWLAREGVRVAPFKAQNMSNNSAVTPDGGEIGRAQAVQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNP+LLKPGGDR+SQ+VV G+V G V+A  Y   +  L  VV D L+ L
Sbjct: 63  AAACGLEPSVRFNPVLLKPGGDRSSQVVVLGKVAGEVSAMSYRERKAELMTVVLDTLAGL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R D +AV+CEGAGSPAEINLRATD+ANMGLARAA LPV+VVGDIDRGG+LAHL GT+A+L
Sbjct: 123 RADHEAVVCEGAGSPAEINLRATDIANMGLARAAGLPVLVVGDIDRGGVLAHLFGTLALL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           +PADQALV+GFVVNKFRGDP+LL PGLRQL ELTGRP +GV+P+ +E+WLD EDS+S   
Sbjct: 183 DPADQALVAGFVVNKFRGDPALLEPGLRQLRELTGRPVHGVLPWREELWLDAEDSLSYAA 242

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
            G++G P+ P G Q L VA +RLPRISN+TD+EALACEPGV VR+VT+ + L  ADLVV+
Sbjct: 243 DGVIGRPQAPVGRQWLRVAVVRLPRISNATDVEALACEPGVSVRFVTEPSRLADADLVVL 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSKATV+DL WLR                     CGG+QML   IDDPVES  G V GL
Sbjct: 303 PGSKATVSDLAWLRR---TGLADAIAAHDGPVLGVCGGYQMLARSIDDPVESGAGPVPGL 359

Query: 364 GLLDADIEFAAQKTLRHWET------PLHGYEIHHGQVARSAETDWLGI---------GL 408
           GLLD D+ F  +K L H  T      P+ GYEIHHG+VAR A+ D  G+         G 
Sbjct: 360 GLLDVDVVFEPEKAL-HRPTGVALGEPVTGYEIHHGRVARRAD-DLPGLVELPGGEVEGA 417

Query: 409 RRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIE 468
            RG V GTHWHGLL+N+  RR +L                          QLDL+ DL+ 
Sbjct: 418 VRGRVVGTHWHGLLENNGFRRAFLRHVAGLAGRDGFEVAPDTDFAARREAQLDLLGDLVV 477

Query: 469 NHLDVGAILDLLEHGAP 485
           +HLD GA+  LLE GAP
Sbjct: 478 DHLDTGAVRALLERGAP 494


>tr|C0ZY63|C0ZY63_RHOE4 Tax_Id=234621 (cobQ)RecName: Full=Cobyric
           acid synthase;[Rhodococcus erythropolis]
          Length = 503

 Score =  533 bits (1374), Expect = e-149
 Identities = 292/503 (58%), Positives = 340/503 (67%), Gaps = 16/503 (3%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGTTSDAGKS+LV GLCR+L R+G+ VAPFKAQNMSNNS VT++GGEI       
Sbjct: 3   GALLVAGTTSDAGKSVLVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PSVRFNP+LLKPG DRTSQLVVRG+   +V A DY+ HR  L AVVA++L SL
Sbjct: 63  ARACGLEPSVRFNPVLLKPGSDRTSQLVVRGKAMTTVGARDYMQHRQWLRAVVAEDLESL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R +FD VICEGAGSPAEINLRATDLANMGLA AA +PV+VVGDIDRGG+LAHL GTVAVL
Sbjct: 123 RSEFDVVICEGAGSPAEINLRATDLANMGLAEAAQIPVVVVGDIDRGGVLAHLFGTVAVL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
            P+DQAL++GFV+NKFRGD +LL PGL QL  LTGRPT GVIPF D++WLD EDS+ V  
Sbjct: 183 SPSDQALIAGFVINKFRGDVALLEPGLDQLRSLTGRPTLGVIPFADDLWLDAEDSLGVTG 242

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
              VG P PP G   LTVAA+RLPRISNSTD+EALACEPGV V WVTD + +  ADLVVI
Sbjct: 243 NAPVGRPGPPVGSAWLTVAAVRLPRISNSTDVEALACEPGVAVSWVTDPSRIRDADLVVI 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSK+TV+DL WLR                     CGG+QML + I D VES  G   GL
Sbjct: 303 PGSKSTVSDLEWLRSTGLADEIIARVGRGQAVLGVCGGYQMLGNSIVDEVESGSGITAGL 362

Query: 364 GLLDADIEFAAQKTLRHWE-----TPLHGYEIHHGQVARSAETDWL----GI--GLRRGA 412
           GLLD DIEFA+ K L           + GYEIHHG+V  + +   L    G+  G  RG+
Sbjct: 363 GLLDLDIEFASDKVLAQVTGSADGISVSGYEIHHGRVVHNGDRPLLADSGGVLEGSVRGS 422

Query: 413 VYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLD 472
           V GTHWHGLL++D  RR  L E                        QLDL+ADL+E HLD
Sbjct: 423 VRGTHWHGLLESDDFRRSLLRE----IAVPGFVAAPDTSVAAVREQQLDLLADLVEQHLD 478

Query: 473 VGAILDLLEHGAP-HRPTMSTAL 494
              +  L+  GAP   P +++AL
Sbjct: 479 QDLLEKLINGGAPIGLPVIASAL 501


>tr|D0LBG3|D0LBG3_GORB4 Tax_Id=526226 (cobQ)RecName: Full=Cobyric
           acid synthase;[Gordonia bronchialis]
          Length = 517

 Score =  506 bits (1304), Expect = e-141
 Identities = 269/505 (53%), Positives = 326/505 (64%), Gaps = 18/505 (3%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GA+L+ GT+SDAGKS++V GLCR LVR+G+ VAPFKAQNMSNNS VT +GGEI       
Sbjct: 6   GAVLIGGTSSDAGKSLVVAGLCRALVREGVRVAPFKAQNMSNNSVVTPDGGEIGRAQALQ 65

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PS RFNP+LLKPGGDR S +V+RGQ  G V AADY+  R+ L  +V DE +SL
Sbjct: 66  AYACGLEPSTRFNPVLLKPGGDRRSHVVLRGQPAGDVGAADYLTWRNRLRELVVDEFTSL 125

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R ++D V+ EGAGS AEINLR +D+AN+GLA+   LPV++V DIDRGG LAHL GT A+L
Sbjct: 126 RGEYDVVVVEGAGSVAEINLRDSDIANLGLAQGCGLPVLLVTDIDRGGSLAHLFGTTAIL 185

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           +PADQAL++GFV+NKFRGDP++L PGL +LAELTGR T GV+P+  ++W+D EDS++   
Sbjct: 186 DPADQALIAGFVINKFRGDPAILQPGLDRLAELTGRRTLGVVPYATDLWIDAEDSLAAPV 245

Query: 244 GGLVGA--------PEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADL 295
           G  VG            P G   LTVAAIRLPRISNSTD+EALACEPGV V WV D   +
Sbjct: 246 GRRVGPALAGSDRDDAAPSGSGRLTVAAIRLPRISNSTDVEALACEPGVDVTWVDDPGSV 305

Query: 296 TGADLVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVES 355
             ADLVV+PG++ATV DL W+RE                    CGGFQML   IDDPVES
Sbjct: 306 AAADLVVVPGTRATVADLTWVRELGIGDALAARARRGGPIVAICGGFQMLARTIDDPVES 365

Query: 356 REGRVDGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWL-----G 405
             GRVDGLGLLD DI F  QKTLR          + GYEIHHGQV  SAE  W+     G
Sbjct: 366 GTGRVDGLGLLDIDIVFGEQKTLRQVHGTVGRRRVTGYEIHHGQVVDSAEQSWIDADGAG 425

Query: 406 IGLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMAD 465
            G  RGA+ GTHWHGLL N+  RRD L                          Q+DL+AD
Sbjct: 426 EGAVRGAIRGTHWHGLLANNDFRRDLLISVAAAAGASGFRPAPDTDVDAIRQAQVDLIAD 485

Query: 466 LIENHLDVGAILDLLEHGAPHRPTM 490
           L+  HLD+ A+  ++       PT+
Sbjct: 486 LLTTHLDMDAVAQIISGPPAAMPTI 510


>sp|A4FM88|COBQ_SACEN Tax_Id=405948 (cobQ)RecName: Full=Cobyric acid
           synthase;[Saccharopolyspora erythraea]
          Length = 519

 Score =  497 bits (1280), Expect = e-138
 Identities = 273/495 (55%), Positives = 319/495 (64%), Gaps = 15/495 (3%)

Query: 5   ALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXXX 64
           ALL+AGTTSDAGKS++  G+CR L R G  VAPFKAQNMSNNS VT +GGEI        
Sbjct: 3   ALLIAGTTSDAGKSVVAAGVCRWLARTGARVAPFKAQNMSNNSVVTPDGGEIGRAQAVQA 62

Query: 65  XXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSLR 124
                 PSVRFNP+LLKPG DR SQ+VV G V+G V A  Y   +  L   V   L  LR
Sbjct: 63  AACGLEPSVRFNPVLLKPGSDRRSQVVVLGHVSGEVTAMSYRERKAALLDTVVSTLDGLR 122

Query: 125 EDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVLE 184
            + D VICEGAGSPAEINLRATD+ANMGLARAA LPV+VVGDIDRGG+ A L GT+A+L+
Sbjct: 123 AEHDHVICEGAGSPAEINLRATDIANMGLARAAGLPVLVVGDIDRGGVFAQLFGTLALLD 182

Query: 185 PADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRPG 244
            ADQALV GFV+NKFRGDP+LL  GL +L  LTGRP +GV+P+ +++WLD EDS+S    
Sbjct: 183 AADQALVGGFVINKFRGDPALLDSGLDRLRALTGRPVHGVLPWAEDLWLDAEDSLSYVAD 242

Query: 245 GLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVIP 304
           G+VG P PPRG Q L VA  RLPRISN+TD+EALA EPGV VR+VT+ + LT ADLVV+P
Sbjct: 243 GVVGRPAPPRGSQWLRVAVPRLPRISNATDVEALAAEPGVAVRFVTEPSRLTDADLVVLP 302

Query: 305 GSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGLG 364
           GSK+TV DL WL +                    CGGFQML  RI D VES  G VDGLG
Sbjct: 303 GSKSTVADLGWLHDTGLADAIRAHAGAGLPVVGICGGFQMLTRRITDQVESGVGAVDGLG 362

Query: 365 LLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGI---------GLRR 410
           +LD +IEF   KTLR      +  P+ GYEIHHG   R  + D  G+         G   
Sbjct: 363 MLDLEIEFEEAKTLRRPSGTAFGEPVDGYEIHHGVPVRRGD-DLAGLVRLPGGTAEGGLS 421

Query: 411 GAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENH 470
           G+V GTHWHGL +NDA RR +LT                         QLDL+ DL+E H
Sbjct: 422 GSVAGTHWHGLFENDAFRRRFLTWAAGCAGRDGFVAAGDTSFAEVRAGQLDLLGDLVEKH 481

Query: 471 LDVGAILDLLEHGAP 485
           LD  AI  LLE GAP
Sbjct: 482 LDTDAIRRLLEGGAP 496


>tr|D3Q7E9|D3Q7E9_STANL Tax_Id=446470 (cobQ)RecName: Full=Cobyric
           acid synthase;[Stackebrandtia nassauensis]
          Length = 512

 Score =  493 bits (1268), Expect = e-137
 Identities = 266/500 (53%), Positives = 325/500 (65%), Gaps = 13/500 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G LLV GT SD+GKS +V GLCR L R+G+ VAPFKAQNMSNNSAVT +GGEI       
Sbjct: 8   GTLLVTGTCSDSGKSTVVAGLCRYLARRGVRVAPFKAQNMSNNSAVTADGGEIGRAQAKQ 67

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  P V FNP+LLKPG D TSQ+VVRG+  G++ AA++   R  L+ VVA+ L+ L
Sbjct: 68  AAAAGLEPDVAFNPVLLKPGSDYTSQIVVRGKPWGTIDAANWPRLRRELSGVVAESLTEL 127

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R  +D VICEGAGSPAEINLRA D+ N+GLAR A +P IVVGDIDRGG+ A L+GT+A+L
Sbjct: 128 RSRYDVVICEGAGSPAEINLRAHDIVNLGLARTADIPTIVVGDIDRGGVFASLYGTLALL 187

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           EPADQ L++GFVVNKFRGD  LL PGL  L ELTGRP YGV+P+  ++WLD EDS+++  
Sbjct: 188 EPADQRLIAGFVVNKFRGDVGLLRPGLDSLTELTGRPVYGVLPWLVDLWLDAEDSLALDA 247

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
           GG++G P PPRGEQ L VA +RLPRISN+TD+EALA EPGV VR  + AADL  ADL+VI
Sbjct: 248 GGVLGRPRPPRGEQWLRVAVVRLPRISNATDVEALAAEPGVRVRITSGAADLAEADLIVI 307

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSK+TV DL WLR+                    CGG+QML   I D VES+ G V GL
Sbjct: 308 PGSKSTVDDLEWLRDNGLDTAIRAHAEAGKPLLGICGGYQMLGRVIRDDVESKRGSVPGL 367

Query: 364 GLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAE-------TDWLGIGLRRG 411
           GLL A+ +FAA KTL H      + P+ GYEIH+G+    A         D  G G R G
Sbjct: 368 GLLPAEFDFAADKTLTHPKGHYGDIPVSGYEIHYGRDTVDAGAASMFRLADGTGEGARLG 427

Query: 412 AVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHL 471
           +V GTHWHG    DA RR +LT                         +LD +ADL+ +HL
Sbjct: 428 SVSGTHWHGAFGCDAFRRAFLTGAAALAGRDRFAVDDTVDFAALRESELDALADLVGDHL 487

Query: 472 DVGAILDLLEHG-APHRPTM 490
           D+ AI  L+  G AP  P++
Sbjct: 488 DMAAITSLIRDGAAPDAPSL 507


>sp|Q6NGL6|COBQ_CORDI Tax_Id=1717 (cobQ)RecName: Full=Cobyric acid
           synthase;[Corynebacterium diphtheriae]
          Length = 479

 Score =  479 bits (1233), Expect = e-133
 Identities = 256/478 (53%), Positives = 307/478 (64%), Gaps = 4/478 (0%)

Query: 5   ALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXXX 64
           + LVAG TSDAGKS++V GLCR L R+GL VAPFKAQNMSNNSAVT +GGEI        
Sbjct: 3   SFLVAGCTSDAGKSVVVAGLCRALTRRGLRVAPFKAQNMSNNSAVTPDGGEIGRAQALQA 62

Query: 65  XXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSLR 124
                 PSV FNPILLKPG DRTSQLVVRG  TG+V+A  YI HR  L  + ++ L+SLR
Sbjct: 63  YACGLTPSVDFNPILLKPGSDRTSQLVVRGIATGNVSARSYIEHRTELRKIASESLNSLR 122

Query: 125 EDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVLE 184
           E FD V+CEGAGSPAE NLRATD+AN GLA    LPV +VGDIDRGG+LAH +GT  +++
Sbjct: 123 ERFDVVVCEGAGSPAETNLRATDVANFGLAEECDLPVYIVGDIDRGGVLAHFYGTHQIVD 182

Query: 185 PADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRPG 244
            AD+A + GFVVNKFRGD S+L PGL+ L +  G PT  V+PF   +W+D EDS+    G
Sbjct: 183 DADRARIKGFVVNKFRGDVSILEPGLQDLEDRLGVPTVAVLPFIHGLWIDAEDSLQSTIG 242

Query: 245 GLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVIP 304
             VG    P G Q L VAAIRLPR+SN+TD+EALACEPGV V W  D   +  ADLVVIP
Sbjct: 243 ATVGPAAAPLGTQRLRVAAIRLPRVSNATDVEALACEPGVTVTWTVDPDSVAEADLVVIP 302

Query: 305 GSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGR-VDGL 363
           GSKAT++DL WLR                     CGGFQM+CS IDDPVES     V+GL
Sbjct: 303 GSKATLSDLAWLRSTGVADAIMERARSQRPILGICGGFQMMCSHIDDPVESGSTTPVEGL 362

Query: 364 GLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWLG-IGLRRGAVYGTHWHGLL 422
           G+ D DIEF  +KTL   E    GYE+HHG+V RS E  W+G  G R  + +GTH HG L
Sbjct: 363 GIFDVDIEFHPEKTLIRHEN--GGYEVHHGRVERSTEQPWIGNEGARTQSNFGTHRHGYL 420

Query: 423 DNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILDLL 480
           ++D  RRD+L                          QLD++AD IE H D+  ++  L
Sbjct: 421 EDDEARRDFLGTVSTLAQRPGFVVAPATSFEAERNKQLDVIADAIEQHWDLDQLIAAL 478


>tr|C5VCT1|C5VCT1_9CORY Tax_Id=553207 (cobQ)RecName: Full=Cobyric
           acid synthase;[Corynebacterium matruchotii ATCC 14266]
          Length = 481

 Score =  479 bits (1232), Expect = e-133
 Identities = 252/475 (53%), Positives = 305/475 (64%), Gaps = 4/475 (0%)

Query: 5   ALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXXX 64
           A LVAG TSDAGKS++V GLCR L R+G  VAPFKAQNMSNNS VT +GGEI        
Sbjct: 3   AFLVAGCTSDAGKSVVVAGLCRALRRRGYRVAPFKAQNMSNNSVVTPDGGEIGRAQALQA 62

Query: 65  XXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSLR 124
                 PS  FNPILLKPG D+TSQLVV GQ  G V+AA YI HR +L  V A  L  L 
Sbjct: 63  VACELEPSTLFNPILLKPGSDKTSQLVVHGQAQGDVSAASYIEHRIYLREVAAQALRDLE 122

Query: 125 EDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVLE 184
            D+D V+CEGAGSPAEINLR TD+AN GLA AA LPV VVGDIDRGG+LAH  GT  +++
Sbjct: 123 ADYDIVVCEGAGSPAEINLRETDIANFGLAAAAQLPVYVVGDIDRGGVLAHFFGTYHIVD 182

Query: 185 PADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRPG 244
            AD+AL+ GFVVNKFRGD S+L PGL +L   TG PT  V+P+   +W+D EDS+  + G
Sbjct: 183 AADRALIRGFVVNKFRGDQSILDPGLAELENRTGVPTVAVLPYIHGLWVDAEDSLQAQVG 242

Query: 245 GLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVIP 304
             +G   P  G Q L +AA+RLPRISN+TD+EALACEPGV V W  D   +  AD+VV+P
Sbjct: 243 ATIGPQRPALGTQRLRIAAVRLPRISNTTDVEALACEPGVSVTWTVDPDYIAEADVVVLP 302

Query: 305 GSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESR-EGRVDGL 363
           GSKATV+DL WLR                     CGGFQM+C  I DPVE+  +  + GL
Sbjct: 303 GSKATVSDLAWLRRQGIADVIVERAAAGRHVVGFCGGFQMMCQHITDPVEAHTDEPIAGL 362

Query: 364 GLLDADIEFAAQKTL-RHWETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGTHWHGLL 422
           G+ DADI F+  KTL RH +T    YE+HHGQV RSAET W+     RG ++GTH HG++
Sbjct: 363 GIFDADIVFSPTKTLIRHADT--GAYEVHHGQVVRSAETVWIDNDCVRGNLFGTHIHGMM 420

Query: 423 DNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAIL 477
           +NDA RR WL +                        QL+ +AD+IE H D+  +L
Sbjct: 421 ENDAFRRAWLRDCAAALGKTGFVVSETTSFATERLNQLETIADVIEAHWDIDGLL 475


>tr|D1A9H5|D1A9H5_THECD Tax_Id=471852 (cobQ)RecName: Full=Cobyric
           acid synthase;[Thermomonospora curvata]
          Length = 501

 Score =  474 bits (1220), Expect = e-131
 Identities = 258/487 (52%), Positives = 308/487 (63%), Gaps = 8/487 (1%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGTTSDAGKS+L  GLCR LVR+G+ VAPFKAQNMS NS VT +G EI       
Sbjct: 3   GALLVAGTTSDAGKSVLTAGLCRWLVRQGVKVAPFKAQNMSLNSMVTADGAEIGRAQAMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  P+   NPILLKPGGDR SQ+V+ G+    V A  Y  HRD L     + L+ L
Sbjct: 63  AQAARIEPTAHMNPILLKPGGDRRSQVVLLGRPVAEVDALGYGAHRDRLRRAALESLAHL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R ++D VICEGAGSPAEINLRA D+ANMGLARAA LPV+VVGDIDRGG+ A L+GTV +L
Sbjct: 123 RAEYDVVICEGAGSPAEINLRAGDIANMGLARAAGLPVLVVGDIDRGGVFAALYGTVGLL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           EPADQAL++GFV+NKFRG P LL PGLR L +LTGRP YGV+P+ D + LD EDS+ +  
Sbjct: 183 EPADQALIAGFVINKFRGAPELLEPGLRMLRDLTGRPVYGVLPWLDGLRLDVEDSLGL-- 240

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
            G   A  PP G +TL VA +RLPRISN TD++ALACEPGV VR+ T   +L  ADLVV+
Sbjct: 241 DGPPAAAGPPHGAETLRVAVVRLPRISNFTDVDALACEPGVTVRYATAPGELADADLVVL 300

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGS+ATV DL WLRE                    CGG+QML   I D VES  G V GL
Sbjct: 301 PGSRATVADLAWLRERGLADQIAARARRGRPVLGICGGYQMLAEEIVDEVESGAGSVPGL 360

Query: 364 GLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGTHW 418
           GLL   +EFA  KTLR      +  P+  YEIHHG    +   +    G R GAV+GT W
Sbjct: 361 GLLPVRVEFARHKTLRRPVGTAYGHPVRAYEIHHGAATVTGPAEPFLDGCRVGAVWGTTW 420

Query: 419 HGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILD 478
           HG L++D  RR++L                          +LD + DL+E HLD  A+  
Sbjct: 421 HGALESDGFRREFL-RRVAEAAGRDFTPAPGVSFGALREARLDALGDLVERHLDTAALWR 479

Query: 479 LLEHGAP 485
           L+E GAP
Sbjct: 480 LIERGAP 486


>tr|A4XAN6|A4XAN6_SALTO Tax_Id=369723 (cobQ)RecName: Full=Cobyric
           acid synthase;[Salinispora tropica]
          Length = 521

 Score =  469 bits (1208), Expect = e-130
 Identities = 256/500 (51%), Positives = 311/500 (62%), Gaps = 20/500 (4%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTV----EGGEIXXX 59
           G LLV GTTSDAGKS+L  G+CR L R+G+ VAPFKAQNMSNNSAV V     GGEI   
Sbjct: 3   GGLLVTGTTSDAGKSVLTAGICRWLHRQGVRVAPFKAQNMSNNSAVVVGPDGHGGEIGRA 62

Query: 60  XXXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADE 119
                      P +RFNP+LLKPG DR+SQ+V+ G+   ++    +   R  LA      
Sbjct: 63  QAMQAAACGLAPDLRFNPVLLKPGSDRSSQVVLLGEAVDTLTTDTFRQLRPRLAETAYAA 122

Query: 120 LSSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGT 179
           L+ LR  +D VICEGAGSP EINLRA D  NMGLAR A LP IVVGDIDRGG+ A + GT
Sbjct: 123 LAELRTSYDVVICEGAGSPTEINLRAGDYVNMGLARHADLPAIVVGDIDRGGVFASMFGT 182

Query: 180 VAVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSV 239
           VA+LEPADQALV+GFV+NKFRGD  LLAPGL  L ++TGRPTYGV+P+  ++WLD EDS+
Sbjct: 183 VALLEPADQALVAGFVINKFRGDRGLLAPGLDMLRQVTGRPTYGVLPWALDLWLDAEDSL 242

Query: 240 SVRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGAD 299
           +   G ++G P  PRG   L VA +RLPRISN+TD+EALA EPGV VR   + A+L  AD
Sbjct: 243 AY--GRVLGRPAAPRGSDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAAD 300

Query: 300 LVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGR 359
           LVV+PGSK+TV DL WLR+                    CGGFQML  RI DPVES +G 
Sbjct: 301 LVVLPGSKSTVADLAWLRQNGLADAVLAHAAAGRPLLGICGGFQMLGRRIHDPVESGQGS 360

Query: 360 VDGLGLLDADIEFAAQKTLRH-----WE-TPLHGYEIHHGQVARSAE--------TDWLG 405
           V GLGLL  ++ F   KT+R      W+  P+ GYEIHHG V+ +A          D  G
Sbjct: 361 VPGLGLLPVEVTFKPSKTVRQSAGTGWDGVPVRGYEIHHGYVSAAAPDLAPLFTYADGTG 420

Query: 406 IGLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMAD 465
            G+  GAVYGTHWHG  ++D  RR +LTE                         LDL+ D
Sbjct: 421 EGVAAGAVYGTHWHGAFESDGFRRRFLTEVARQAGRPGFRAAPDTSFAGARERSLDLLGD 480

Query: 466 LIENHLDVGAILDLLEHGAP 485
           L+E HLD   +  L++ G P
Sbjct: 481 LVEEHLDTAVLWRLIDTGPP 500


>tr|A8M1Q8|A8M1Q8_SALAI Tax_Id=391037 SubName: Full=Cobyric acid
           synthase CobQ;[Salinispora arenicola]
          Length = 575

 Score =  468 bits (1203), Expect = e-129
 Identities = 258/498 (51%), Positives = 309/498 (62%), Gaps = 20/498 (4%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTV----EGGEIXXX 59
           G LLVAGTTSDAGKS+L  G+CR L R+G+ VAPFKAQNMSNNSAV V     GGEI   
Sbjct: 3   GGLLVAGTTSDAGKSVLTAGICRWLHRRGVRVAPFKAQNMSNNSAVVVGPDGRGGEIGRA 62

Query: 60  XXXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADE 119
                      P +RFNP+LLKPG DRTSQ+V+ G+   ++    +   R  LA      
Sbjct: 63  QAMQAAACGLAPDLRFNPVLLKPGSDRTSQVVLLGEAVDTLTTGTFRQLRPRLADTAYAA 122

Query: 120 LSSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGT 179
           L+ LR   D VICEGAGSPAEINLRA D  NMGLAR A LP IVVGDIDRGG+ A + GT
Sbjct: 123 LADLRATHDVVICEGAGSPAEINLRAGDYVNMGLARHAGLPAIVVGDIDRGGVFASMFGT 182

Query: 180 VAVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSV 239
           VA+LEPADQALV+GFV+NKFRGDPSLLAPGL  L ++TGRPTYGV+P+  ++WLD EDS+
Sbjct: 183 VALLEPADQALVAGFVINKFRGDPSLLAPGLDMLRQVTGRPTYGVLPWALDLWLDAEDSL 242

Query: 240 SVRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGAD 299
           +   G ++G P  PRG   L VA +RLPRISN+TD+EALA EPGV VR   + A+L  AD
Sbjct: 243 AY--GRVLGRPAAPRGSDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAAD 300

Query: 300 LVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGR 359
           LVV+PGSK+TV DL WLR+                    CGGFQML   I DPVESR G 
Sbjct: 301 LVVLPGSKSTVADLDWLRQSGLADAVLAHAAAGRPLLGVCGGFQMLGRLIHDPVESRRGS 360

Query: 360 VDGLGLLDADIEFAAQKTLRH-----WET-PLHGYEIHHGQVARSAET--------DWLG 405
           V GLGLL  ++ F   KT+R      W+  P+ GYEIHHG V+ +A          D  G
Sbjct: 361 VPGLGLLPVEVTFDPCKTVRRSAGIGWDAEPVGGYEIHHGYVSAAAPDLAPLFAYHDGTG 420

Query: 406 IGLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMAD 465
            G   G+VYGTHWHG  ++D  RR +L                           LDL+ D
Sbjct: 421 EGAVAGSVYGTHWHGAFESDGFRRRFLARVARQAGRHGFQVAPDTSFAGARERSLDLLGD 480

Query: 466 LIENHLDVGAILDLLEHG 483
           L+E HLD   +  L+E G
Sbjct: 481 LVEEHLDTAGLWRLIESG 498


>tr|C4RPI9|C4RPI9_9ACTO Tax_Id=219305 (cobQ)RecName: Full=Cobyric
           acid synthase;[Micromonospora sp. ATCC 39149]
          Length = 514

 Score =  468 bits (1203), Expect = e-129
 Identities = 256/502 (50%), Positives = 312/502 (62%), Gaps = 22/502 (4%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTV----EGGEIXXX 59
           G LLVAGTTSDAGKS+L  G+CR L R+G+ VAPFKAQNMSNNSAV V     GGEI   
Sbjct: 3   GGLLVAGTTSDAGKSVLTAGICRWLRRRGVKVAPFKAQNMSNNSAVVVGPDGRGGEIGRA 62

Query: 60  XXXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADE 119
                        +RFNP+LLKPG DR+SQ+V+ G+   +V A +Y   R  LA      
Sbjct: 63  QAMQAAACGVAADLRFNPVLLKPGSDRSSQVVLLGEAVDTVTAGNYHALRPRLAEAAFAS 122

Query: 120 LSSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGT 179
           L+ LRE ++ V+CEGAGSPAEINLRA D  NMGLAR A LP IVVGDIDRGG+ A + GT
Sbjct: 123 LAELREAYEVVVCEGAGSPAEINLRAGDYVNMGLARHAGLPTIVVGDIDRGGVFASMFGT 182

Query: 180 VAVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSV 239
           VA+L+PADQALV+GFV+NKFRGD  LL PGL  L  +TGRPTYGV+P+H ++WLD EDS+
Sbjct: 183 VALLDPADQALVAGFVINKFRGDRGLLQPGLDMLTRVTGRPTYGVLPWHLDLWLDAEDSL 242

Query: 240 SVRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGAD 299
           +   G ++G P  P G   L VA +RLPRISN+TD+EALA EPGV VR   + A+L  AD
Sbjct: 243 AY--GRVLGRPAAPHGTDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAAD 300

Query: 300 LVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGR 359
           +VV+PGSK+TV DL WLR                     CGGFQML   + DPVESR G 
Sbjct: 301 IVVLPGSKSTVADLAWLRRTGLADAVAAHAAAGKPLLGICGGFQMLGRAVHDPVESRAGS 360

Query: 360 VDGLGLLDADIEFAAQKTLRHWE--------TPLHGYEIHHGQVARS--------AETDW 403
           V GLGLL  ++ FAA+KT+R            P+ GYEIHHG V+ +        +  D 
Sbjct: 361 VAGLGLLPVEVTFAARKTVRQAAGTAAADAGVPVRGYEIHHGYVSSADPALPPLLSYDDG 420

Query: 404 LGIGLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLM 463
            G G   GAV GTHWHG  ++DA RR +LT+                         LDL+
Sbjct: 421 TGEGAVLGAVCGTHWHGAFESDAFRRRFLTDAARLAGRTGFRVAPDTSFAAARERSLDLL 480

Query: 464 ADLIENHLDVGAILDLLEHGAP 485
            DL+E HLD  A+  L+E G P
Sbjct: 481 GDLVEEHLDTAALWRLIECGPP 502


>tr|D3C373|D3C373_9ACTO Tax_Id=648999 (cobQ)RecName: Full=Cobyric
           acid synthase;[Micromonospora sp. L5]
          Length = 514

 Score =  467 bits (1201), Expect = e-129
 Identities = 257/500 (51%), Positives = 307/500 (61%), Gaps = 20/500 (4%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTV----EGGEIXXX 59
           G LLVAGTTSDAGKS+L  G+CR L R+G+ VAPFKAQNMSNNSAV V     GGE+   
Sbjct: 3   GGLLVAGTTSDAGKSVLTAGICRWLRRRGVRVAPFKAQNMSNNSAVVVGPDGRGGELGRA 62

Query: 60  XXXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADE 119
                        +RFNP+LLKPG D  SQ+V+ G+   +V A +Y   R  LA      
Sbjct: 63  QAMQAAACGLDADLRFNPVLLKPGSDHASQVVLLGEAVDTVTAGNYHEVRSRLATTAYAA 122

Query: 120 LSSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGT 179
           L+ LR ++D VICEGAGSPAEINLR  D  NMGLAR A LP IVVGDIDRGG+ A + GT
Sbjct: 123 LAELRSEYDVVICEGAGSPAEINLRDGDYVNMGLARQAGLPTIVVGDIDRGGVFASMFGT 182

Query: 180 VAVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSV 239
           VA+L+ ADQAL++GFVVNKFRGD  LL PGL  L  +TGRPTYGV+P+  ++WLD EDS+
Sbjct: 183 VALLDAADQALLAGFVVNKFRGDRGLLQPGLDMLRRVTGRPTYGVVPWALDLWLDAEDSL 242

Query: 240 SVRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGAD 299
           +   G ++G P  PRG   L VA +RLPRISN+TD+EALA EPGV VR   + A+L  AD
Sbjct: 243 AY--GRVLGRPPAPRGTDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAAD 300

Query: 300 LVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGR 359
           LVV+PG+K+TV DL WLRE                    CGGFQML   I D VESR G 
Sbjct: 301 LVVLPGTKSTVADLAWLRETGLADAVRAHAAAGRPLLGICGGFQMLGRAIHDAVESRRGT 360

Query: 360 VDGLGLLDADIEFAAQKTLRHWE------TPLHGYEIHHGQVARS--------AETDWLG 405
           V GLGLL  +I F  +KT+R  E       P+HGYEIHHG+V  +           D  G
Sbjct: 361 VPGLGLLPVEITFEPRKTVRRAEGTAAGDVPVHGYEIHHGRVTAADPGLAPLLRYADGTG 420

Query: 406 IGLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMAD 465
            G R G VYGTHWHG   +DA RR +LTE                         LDL+ D
Sbjct: 421 EGARLGTVYGTHWHGAFSSDAFRRRFLTEVAEAAGRTGFKVAPDTSFAAAGERTLDLLGD 480

Query: 466 LIENHLDVGAILDLLEHGAP 485
           L+E HLD  A+  L+E G P
Sbjct: 481 LVEEHLDTDALWRLIESGPP 500


>tr|D1S4Z9|D1S4Z9_9ACTO Tax_Id=644283 (cobQ)RecName: Full=Cobyric
           acid synthase;[Micromonospora aurantiaca ATCC 27029]
          Length = 514

 Score =  467 bits (1201), Expect = e-129
 Identities = 257/500 (51%), Positives = 308/500 (61%), Gaps = 20/500 (4%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTV----EGGEIXXX 59
           G LLVAGTTSDAGKS+L  G+CR L R+G+ VAPFKAQNMSNNSAV V     GGE+   
Sbjct: 3   GGLLVAGTTSDAGKSVLTAGICRWLRRRGVRVAPFKAQNMSNNSAVVVGPDGRGGELGRA 62

Query: 60  XXXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADE 119
                        +RFNP+LLKPG D  SQ+V+ G+   +V A +Y   R  LA+     
Sbjct: 63  QAMQAAACGLDADLRFNPVLLKPGSDHASQVVLLGEAVDTVTAGNYHEVRSRLASTAYAA 122

Query: 120 LSSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGT 179
           L+ LR ++D VICEGAGSPAEINLR  D  NMGLAR A LP IVVGDIDRGG+ A + GT
Sbjct: 123 LAELRSEYDVVICEGAGSPAEINLRDGDYVNMGLARQAGLPTIVVGDIDRGGVFASMFGT 182

Query: 180 VAVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSV 239
           VA+L+ ADQAL++GFVVNKFRGD  LL PGL  L  +TGRPTYGV+P+  ++WLD EDS+
Sbjct: 183 VALLDAADQALLAGFVVNKFRGDRGLLQPGLDMLHRVTGRPTYGVVPWALDLWLDAEDSL 242

Query: 240 SVRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGAD 299
           +   G ++G P  PRG   L VA +RLPRISN+TD+EALA EPGV VR   + A+L  AD
Sbjct: 243 AY--GRVLGRPPAPRGTDWLDVAVVRLPRISNATDVEALATEPGVRVRLTVEPAELAAAD 300

Query: 300 LVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGR 359
           LVV+PG+K+TV DL WLRE                    CGGFQML   I D VESR G 
Sbjct: 301 LVVLPGTKSTVADLAWLRETGLADAVRAHAAAGRPLLGICGGFQMLGRAIHDAVESRRGT 360

Query: 360 VDGLGLLDADIEFAAQKTLRHWE------TPLHGYEIHHGQVARS--------AETDWLG 405
           V GLGLL  +I F  +KT+R  E       P+HGYEIHHG+V  +           D  G
Sbjct: 361 VPGLGLLPVEITFEPRKTVRRAEGTAAGDVPVHGYEIHHGRVTAADPGLAPLLRYADGTG 420

Query: 406 IGLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMAD 465
            G R G VYGTHWHG   +DA RR +LTE                         LDL+ D
Sbjct: 421 EGARLGTVYGTHWHGAFSSDAFRRRFLTEVAEAAGRTGFKVAPDTSFAAARERTLDLLGD 480

Query: 466 LIENHLDVGAILDLLEHGAP 485
           L+E HLD  A+  L+E G P
Sbjct: 481 LVEEHLDTDALWRLIESGPP 500


>tr|D5UM31|D5UM31_TSUPA Tax_Id=521096 SubName: Full=Cobyric acid
           synthase CobQ;[Tsukamurella paurometabola DSM 20162]
          Length = 507

 Score =  464 bits (1195), Expect = e-128
 Identities = 264/504 (52%), Positives = 310/504 (61%), Gaps = 24/504 (4%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVE----GGEIXXX 59
           GALL+AG TSDAGKS +  GLCRLL R+G+ VAPFKAQNMSNNS  TVE     GEI   
Sbjct: 3   GALLIAGATSDAGKSTITAGLCRLLARRGVRVAPFKAQNMSNNSVATVETDGTSGEIGRA 62

Query: 60  XXXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADE 119
                      PS RFNP+LLKPG DR SQL++ G+  G V A DYI  R  L   V   
Sbjct: 63  QATQALACGLAPSTRFNPVLLKPGSDRRSQLILHGRPVGDVGARDYITRRQWLLDEVTTT 122

Query: 120 LSSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGT 179
           L  LR++FD V+CEGAGSPAEINLRATD+ANMGLARAA LP +VVGDIDRGG+LAHL GT
Sbjct: 123 LQRLRDEFDVVLCEGAGSPAEINLRATDIANMGLARAAGLPTVVVGDIDRGGVLAHLAGT 182

Query: 180 VAVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSV 239
           VAVL+P DQ  +  F++N+FRGD SLL PGL QL ++T RPT GV+P+  ++WLD EDS+
Sbjct: 183 VAVLDPDDQRHIYAFLINRFRGDVSLLTPGLEQLEDITRRPTVGVLPYLTDLWLDAEDSL 242

Query: 240 SVRPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGAD 299
           +     LVG     R    L VAAI LPR+SN+TD+EALACEPG+ VRW T  AD+  AD
Sbjct: 243 AALGSDLVGPGS--RRPDPLRVAAIALPRVSNTTDVEALACEPGLTVRWTTRPADVAAAD 300

Query: 300 LVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDP--VESRE 357
           LVV+PG+KATV DL WLRE                    CGG+QML   I DP  +E+  
Sbjct: 301 LVVLPGTKATVADLAWLRERGLADALVARAAGGRPIIGVCGGYQMLGRSIGDPHGIEAPV 360

Query: 358 G-RVDGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWL-----GI 406
           G RVDGLGLLD DIEFAA K +R+           GYEIHHG V RS E+  L       
Sbjct: 361 GSRVDGLGLLDLDIEFAADKCVRNVAGTGLGVRATGYEIHHGTVVRSTESHLLDGPDGAE 420

Query: 407 GLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADL 466
           G   G V GTHWHGLL +D  RR +L                          QLD +AD 
Sbjct: 421 GALAGPVLGTHWHGLLGSDEFRRAYL-----HRAFPGFDPGPVTSYDGARIAQLDRIADA 475

Query: 467 IENHLDVGAILDLLEHGAPHRPTM 490
           IE H DV AI+  L+      P +
Sbjct: 476 IEEHCDVDAIVAPLQLSGVFSPIL 499


>tr|D2BE39|D2BE39_STRRD Tax_Id=479432 (cobQ)RecName: Full=Cobyric
           acid synthase; Flags: Precursor;[Streptosporangium
           roseum]
          Length = 509

 Score =  462 bits (1190), Expect = e-128
 Identities = 258/487 (52%), Positives = 315/487 (64%), Gaps = 13/487 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G+LLVAGTTSDAGKS++  G+CR L R+G+ VAP+KAQNMS NS VT +G EI       
Sbjct: 3   GSLLVAGTTSDAGKSVVTAGICRWLARQGVKVAPYKAQNMSLNSFVTADGAEIGRAQAMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  PS   NPILLKPG DR SQ+VV G+    V A +Y + +D L  V  D L  L
Sbjct: 63  AAACGLEPSADMNPILLKPGSDRRSQVVVMGRPLADVDAMEYWDVKDRLRQVAVDALERL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R+ +D V+CEGAGSPAEINLR  D+ANMGLARAA+LPVIVVGDIDRGG+ A L+GTVA+L
Sbjct: 123 RDTYDVVVCEGAGSPAEINLRRGDIANMGLARAASLPVIVVGDIDRGGVFASLYGTVALL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           EPADQAL++GFV+NKFRG   LL PGL  + +LTGR  YGV+P+ D +WLD EDS+++  
Sbjct: 183 EPADQALIAGFVINKFRGARELLEPGLDMIRDLTGREVYGVLPWLDGLWLDVEDSLALDN 242

Query: 244 GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
              +GA   P G QTL VA +RLPRISN TD++ALA EPGVVVR+VT  A+L  ADLVV+
Sbjct: 243 RPAIGA-RTPYGRQTLRVAVVRLPRISNFTDVDALASEPGVVVRFVTSPAELDDADLVVL 301

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGS+ATV+DL WLR                     CGG+QML   I D VES  GRV+GL
Sbjct: 302 PGSRATVSDLAWLR-----ATGLADALRGRVVLGICGGYQMLARTIHDGVESGAGRVEGL 356

Query: 364 GLLDADIEFAAQKTLRHWETPLHG-----YEIHHGQVARSAETDWLGIGLRRGAVYGTHW 418
           GLL A +EFAA+KTL       +G     YEIHHG V       +L  G R G+V+GT W
Sbjct: 357 GLLPATVEFAAEKTLGRPVGEAYGCRVAAYEIHHGVVTAEGGDPFLD-GCRSGSVWGTTW 415

Query: 419 HGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILD 478
           HG L+ND  RR +L +                        +LD + DLIE+H+D  A+L 
Sbjct: 416 HGALENDDFRRAFLAD-VAAVSGRDFTPAPDVSFAALREERLDALGDLIEHHVDTAALLR 474

Query: 479 LLEHGAP 485
           LLE GAP
Sbjct: 475 LLEGGAP 481


>tr|C2GKW2|C2GKW2_9CORY Tax_Id=548478 (cobQ)RecName: Full=Cobyric
           acid synthase;[Corynebacterium glucuronolyticum ATCC
           51866]
          Length = 472

 Score =  457 bits (1177), Expect = e-126
 Identities = 243/475 (51%), Positives = 304/475 (64%), Gaps = 14/475 (2%)

Query: 5   ALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXXX 64
           A+L+ GTTSDAGKS+LV GLCR L R+G+SVAPFKAQNMSNNSAV   GGEI        
Sbjct: 3   AVLICGTTSDAGKSVLVAGLCRALARRGVSVAPFKAQNMSNNSAVCPTGGEIGRAQALQA 62

Query: 65  XXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSLR 124
                 P VRFNP+LLKPG DR SQ+VV G+V G V A DY   R  +  V A+ L  L 
Sbjct: 63  FACGLEPEVRFNPVLLKPGSDRRSQVVVLGRVEGDVGAKDYFTRRTRMREVAAETLRELE 122

Query: 125 EDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVLE 184
            ++D V+CEGAGSPAE NLRATD+AN GLA A  L V VVGDIDRGG+LAHL GT  +++
Sbjct: 123 REYDIVVCEGAGSPAETNLRATDVANFGLAEACDLDVYVVGDIDRGGVLAHLFGTYHIVD 182

Query: 185 PADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRPG 244
            AD+A + GF++NKFRGDP +L PGL  L   TG PT G++PF D +W+D EDS+    G
Sbjct: 183 EADRARIKGFIINKFRGDPDILQPGLDDLYARTGVPTIGILPFIDGLWIDAEDSLQSAEG 242

Query: 245 GLVG-APEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
            +VG A     GE+T++VAA+RLPR+SN+TD+EALA EP   V W +D   +  ADLVV+
Sbjct: 243 RIVGLAASVAPGEKTISVAAVRLPRVSNATDVEALAAEPATTVTWTSDPGLVRSADLVVV 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSKATVTDL W+R                     CGG+QML   I+D VES  G+  GL
Sbjct: 303 PGSKATVTDLEWMR---GNGIADALCQRTEPILAICGGYQMLGKSIEDDVESHRGKTRGL 359

Query: 364 GLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWL-GIGLRRGAVYGTHWHGLL 422
           GL D DI F  +KTL+ W  P   YEIHHG+VAR+ +  WL G G R   ++GTH HG++
Sbjct: 360 GLFDLDIAFHPEKTLKRW--PDGTYEIHHGRVARNGDPTWLDGEGSRVRNLWGTHRHGVM 417

Query: 423 DNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAIL 477
           D+D  R+D+L+E                        Q+DL+AD +E HLD+ A +
Sbjct: 418 DDDERRKDFLSE-------VFSLPRSQASSAGERMKQVDLLADAVEEHLDMDAFI 465


>tr|C0VVE1|C0VVE1_9CORY Tax_Id=548477 (cobQ)RecName: Full=Cobyric
           acid synthase;[Corynebacterium glucuronolyticum ATCC
           51867]
          Length = 472

 Score =  456 bits (1174), Expect = e-126
 Identities = 243/475 (51%), Positives = 304/475 (64%), Gaps = 14/475 (2%)

Query: 5   ALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXXX 64
           A+L+ GTTSDAGKS+LV GLCR L R+G+SVAPFKAQNMSNNSAV   GGEI        
Sbjct: 3   AVLICGTTSDAGKSVLVVGLCRALARRGVSVAPFKAQNMSNNSAVCPTGGEIGRAQALQA 62

Query: 65  XXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSLR 124
                 P VRFNP+LLKPG DR SQ+VV G+V G V A DY   R  +  V A+ L  L 
Sbjct: 63  FACGLEPEVRFNPVLLKPGSDRRSQVVVLGRVEGDVGAKDYFTRRTRMREVAAETLRELE 122

Query: 125 EDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVLE 184
            ++D V+CEGAGSPAE NLRATD+AN GLA A  L V VVGDIDRGG+LAHL GT  +++
Sbjct: 123 REYDIVVCEGAGSPAETNLRATDVANFGLAEACDLDVYVVGDIDRGGVLAHLFGTYHIVD 182

Query: 185 PADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRPG 244
            AD+A + GF++NKFRGDP +L PGL  L   TG PT G++PF D +W+D EDS+    G
Sbjct: 183 EADRARIKGFIINKFRGDPDILQPGLDDLYARTGVPTIGILPFIDGLWIDAEDSLQSAEG 242

Query: 245 GLVG-APEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLVVI 303
            +VG A     GE+T++VAA+RLPR+SN+TD+EALA EP   V W +D   +  ADLVV+
Sbjct: 243 RIVGLAASVAPGEKTISVAAVRLPRVSNATDVEALAAEPATTVTWTSDPGLVRSADLVVV 302

Query: 304 PGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVDGL 363
           PGSKATVTDL W+R                     CGG+QML   I+D VES  G+  GL
Sbjct: 303 PGSKATVTDLEWMR---GNGIADALCQRTEPILAICGGYQMLGKSIEDDVESHRGKTRGL 359

Query: 364 GLLDADIEFAAQKTLRHWETPLHGYEIHHGQVARSAETDWL-GIGLRRGAVYGTHWHGLL 422
           GL D DI F  +KTL+ W  P   YEIHHG+VAR+ +  WL G G R   ++GTH HG++
Sbjct: 360 GLFDLDIAFHPEKTLKRW--PDGTYEIHHGRVARNGDPTWLDGEGSRVRNLWGTHRHGVM 417

Query: 423 DNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAIL 477
           D+D  R+D+L+E                        Q+DL+AD +E HLD+ A +
Sbjct: 418 DDDERRKDFLSE-------VFSLPRSQASSAGERMKQVDLLADAVEEHLDMDAFI 465


>tr|D2S739|D2S739_GEOOG Tax_Id=526225 SubName: Full=Cobyric acid
           synthase CobQ;[Geodermatophilus obscurus]
          Length = 511

 Score =  438 bits (1127), Expect = e-121
 Identities = 245/489 (50%), Positives = 294/489 (60%), Gaps = 8/489 (1%)

Query: 2   TGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXX 61
           +GGALLVAGTTSDAGKS++  G+CR LVR+G+SVAPFKAQNMSNNS VT +G EI     
Sbjct: 11  SGGALLVAGTTSDAGKSVVTAGICRWLVRQGVSVAPFKAQNMSNNSMVTPDGAEIGRAQV 70

Query: 62  XXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELS 121
                    P    NP+LLKPGG+ +SQ+VV G     V A  Y   +  L   V   L 
Sbjct: 71  MQAAAARVEPEAAMNPVLLKPGGEDSSQVVVLGHAVADVTALSYRPMKAALMEQVLASLE 130

Query: 122 SLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVA 181
            LR  FD V+CEGAGSP EINLRA D+ANMGLA AA LPV+VVGDIDRGG+   L+GTVA
Sbjct: 131 DLRSRFDVVVCEGAGSPTEINLRADDIANMGLATAAGLPVVVVGDIDRGGVFPALYGTVA 190

Query: 182 VLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSV 241
           ++ PADQ LV+GF+VNKFRGD  LL PGL QL  LTGRPT GV+P+     +D EDS+ V
Sbjct: 191 LMPPADQRLVAGFLVNKFRGDVRLLGPGLEQLTALTGRPTLGVLPWLPGAAVDVEDSLGV 250

Query: 242 RPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLV 301
             G       PP GE+ L VA  RLPR+SN TD++ALA EPGV+VR+ T   +L  ADLV
Sbjct: 251 PTG--ASPTGPPHGEEVLRVAVARLPRLSNFTDLDALAAEPGVLVRYATSPEELGDADLV 308

Query: 302 VIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVD 361
           V+PG++ATV DL WLR                     CGG QML   I D VESR G V 
Sbjct: 309 VLPGTRATVADLGWLRATGLADAVARHAAAGRPVLGVCGGSQMLARTITDDVESRAGTVP 368

Query: 362 GLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGT 416
           GLGLL AD+ FA +KTL       +   + GYEIHHG V      +    G R G+V+GT
Sbjct: 369 GLGLLPADVRFAPEKTLGRPVGTAFGQEVRGYEIHHGVVIVDDAAERFLDGARAGSVFGT 428

Query: 417 HWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAI 476
            WHG L+ D  RR +LTE                        +LD + DL+  H D  A+
Sbjct: 429 TWHGALEGDGFRRAFLTE-VARVAGRRFVAAPDTDFAAVRERRLDALGDLVAEHADTDAL 487

Query: 477 LDLLEHGAP 485
             L+E G P
Sbjct: 488 WRLVEDGVP 496


>tr|Q0RLS3|Q0RLS3_FRAAA Tax_Id=326424 (bioD)SubName:
           Full=Dethiobiotin synthetase (Cobyric acid synthase);
           EC=6.3.3.3;[Frankia alni]
          Length = 531

 Score =  437 bits (1125), Expect = e-120
 Identities = 253/510 (49%), Positives = 309/510 (60%), Gaps = 31/510 (6%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G LLVAGT SDAGKS+L  G+CR L R+G+ VAPFKAQNM+ NS VT +G EI       
Sbjct: 14  GGLLVAGTASDAGKSVLTAGICRWLAREGVRVAPFKAQNMALNSTVTADGAEIGRAQAMQ 73

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  P    NP+LLKPGGDR SQL+V G+    V A  Y  H++ LA +V + L  L
Sbjct: 74  AAAAGVEPEAAMNPVLLKPGGDRHSQLIVLGRPVAEVDALGYRPHKERLAKIVLECLDDL 133

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R  FDAVICEGAGSPAEINLR+TD+ANMGLARAA LPVIVVGDID+GG+ A L GT+A+L
Sbjct: 134 RGRFDAVICEGAGSPAEINLRSTDIANMGLARAANLPVIVVGDIDKGGVFAALFGTLALL 193

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSV-- 241
           + ADQALV+G+V+N+FRGD  LL PGLRQ+  LTGRP +GV+PF   +WLD EDS+ +  
Sbjct: 194 DRADQALVAGWVINRFRGDARLLEPGLRQIEALTGRPVHGVVPFRSGLWLDVEDSLDLTS 253

Query: 242 -------RPGGLVGAPEPPRGE----------QTLTVAAIRLPRISNSTDIEALACEPGV 284
                     GL G  +   GE          ++L VA +RLPR+SN TD++AL  EPGV
Sbjct: 254 YPDAEPDTDSGLAG-EDASAGEGASAGDGVRRESLRVAVVRLPRLSNVTDLDALRAEPGV 312

Query: 285 VVRWVTDAADLTGADLVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQM 344
           VVR VT   +L  ADLVV+PG+++TV DLRWLR                     CGG+QM
Sbjct: 313 VVRLVTGPDELADADLVVLPGTRSTVEDLRWLRRRGLADAVAARVAAGRPVLGICGGYQM 372

Query: 345 LCSRIDDPVESREGRVDGLGLLDADIEFAAQKTL-RHWET-----PLHGYEIHHGQVA-- 396
           L  RI D VES  G V GLGLL     F A K L R   T     P+ GYEI HG++A  
Sbjct: 373 LGRRIHDDVESGAGEVAGLGLLPVTTTFEASKLLGRRAATDAAGRPVTGYEIRHGRLAIA 432

Query: 397 -RSAETDWLGIGLRRGAVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXX 455
              A   +   G+R GAV GT WHGLL+ND  RR +LTE                     
Sbjct: 433 DHPAAEPFAADGVRVGAVAGTSWHGLLENDEFRRAYLTE--VARAAGRAFVPARTRFADV 490

Query: 456 XXXQLDLMADLIENHLDVGAILDLLEHGAP 485
              +LD++ DL+  HLD  A+  LL+ GAP
Sbjct: 491 RRRRLDVLGDLVAEHLDTAALRRLLDEGAP 520


>tr|D6M2X5|D6M2X5_9ACTO Tax_Id=465543 SubName: Full=Cobyric acid
           synthase CobQ;[Streptomyces sp. SPB74]
          Length = 504

 Score =  437 bits (1124), Expect = e-120
 Identities = 250/494 (50%), Positives = 302/494 (61%), Gaps = 11/494 (2%)

Query: 1   MTGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXX 60
           MTGG LLVAGTTSDAGKS++  G+CR L R+G+ VAPFK QNMS NS VT EG EI    
Sbjct: 1   MTGGGLLVAGTTSDAGKSVVTAGICRWLARRGVRVAPFKGQNMSLNSFVTREGAEIGRAQ 60

Query: 61  XXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRD-HLAAVVADE 119
                     P    NP+LLKPGG+R+SQ+V+ G+  G ++A  Y   R   L   V D 
Sbjct: 61  AMQARAARVEPHALMNPVLLKPGGERSSQVVLLGKPLGELSARGYHGGRQAELFGTVVDC 120

Query: 120 LSSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGT 179
           L+ LR  +DAVICEGAGSPAEINLR TDL NMG+ARAA LPV+VVGDIDRGG+ A   GT
Sbjct: 121 LAELRRTYDAVICEGAGSPAEINLRRTDLVNMGIARAAQLPVVVVGDIDRGGVFASFFGT 180

Query: 180 VAVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSV 239
            A+L   DQALV+G++VNKFRGD SLL PGLR L +LTGR T+GV+PF   + +D ED +
Sbjct: 181 TALLSAEDQALVAGYLVNKFRGDVSLLEPGLRMLRDLTGRDTFGVLPFRPGLGIDEEDGM 240

Query: 240 SVRPGGLVGAPE--PPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTG 297
           +V   G V       P GE+ L VA   +P +SN TD++ALA EPGVVVR+V  A DL  
Sbjct: 241 AVSLRGAVRESRLAEPYGEEVLRVAVCAVPLLSNFTDVDALAAEPGVVVRFVDRAQDLLD 300

Query: 298 ADLVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESRE 357
           ADLVV+PG++ TV  L WLRE                    CGGFQ+L   I+D VESR 
Sbjct: 301 ADLVVVPGTRGTVRALEWLRERGLADALARRAAEGRPVLGICGGFQLLGELIEDEVESRA 360

Query: 358 GRVDGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHG-QVARSAETDWLGIGLRRG 411
           G V GLGLL   + FA +KTL          P+ GYEIHHG    R  +  +L  G R G
Sbjct: 361 GTVAGLGLLPVRVRFAREKTLARPSGTALGEPVEGYEIHHGIAEVRGGDEPFLD-GCRVG 419

Query: 412 AVYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHL 471
           AV+GTHWHG L++D  RR +L                          QLD +ADLIE H 
Sbjct: 420 AVWGTHWHGSLESDGFRRAFLGR-VAAQAGRRFVPAPGTEFGALREEQLDALADLIEEHA 478

Query: 472 DVGAILDLLEHGAP 485
           D  A+L L+E GAP
Sbjct: 479 DTRALLGLIERGAP 492


>tr|A8LG25|A8LG25_FRASN Tax_Id=298653 (cobQ)RecName: Full=Cobyric
           acid synthase; Flags: Precursor;[Frankia sp.]
          Length = 508

 Score =  436 bits (1120), Expect = e-120
 Identities = 245/493 (49%), Positives = 301/493 (61%), Gaps = 12/493 (2%)

Query: 3   GGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXX 62
           GGALLVAGT SDAGKS+L  GLCR L R+G+ VAPFKAQNM+ NS VT +G EI      
Sbjct: 7   GGALLVAGTASDAGKSVLTAGLCRWLAREGVRVAPFKAQNMALNSVVTADGAEIGRAQAM 66

Query: 63  XXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSS 122
                   P    NP+LLKPG DR SQLVV G+    V A  Y  H++ L  +V D L+ 
Sbjct: 67  QAAAAGVEPEAAMNPVLLKPGSDRHSQLVVLGRPVAEVDALGYRPHKERLLGIVLDCLAD 126

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LR  FDAVICEGAGSPAEINLRATD+ANMGLARAA LPV+VVGDIDRGG+ A L GT+A+
Sbjct: 127 LRGRFDAVICEGAGSPAEINLRATDIANMGLARAANLPVLVVGDIDRGGVFAALFGTLAL 186

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           L+ ADQ  ++G+V+N+FRGD  LL PGLRQL  LTGRP  GV+P+   +WLD EDS+ +R
Sbjct: 187 LDRADQTHIAGWVINRFRGDARLLEPGLRQLEGLTGRPVLGVLPWLPGLWLDVEDSLDLR 246

Query: 243 ---PGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGAD 299
                   G+     G   L VA +R PR+SN TD++AL  EPGV VR  T   ++   D
Sbjct: 247 SHPDPEADGSGAADTGPDRLRVAVVRFPRLSNITDLDALRAEPGVSVRLATTPDEIADVD 306

Query: 300 LVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGR 359
           LVV+PG++ATV+DL WLR                     CGG+QML  RI+D +ES  G 
Sbjct: 307 LVVLPGTRATVSDLAWLRRRGLAGALAARATAGLPILGICGGYQMLGVRIEDEIESGAGE 366

Query: 360 VDGLGLLDADIEFAAQKTL--RHWET----PLHGYEIHHGQVARSAETDWLGI-GLRRGA 412
           V GLGLL     FAA K L  RH  +    P+ GYEI HG+ A     +   + G+RRG 
Sbjct: 367 VPGLGLLPLVTRFAADKVLGRRHGVSADGHPVTGYEIRHGRPAADDSLEPFAVDGVRRGG 426

Query: 413 VYGTHWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLD 472
           VYGT WHGLL+ND  RR +LT                         +LD + DL+ +HLD
Sbjct: 427 VYGTSWHGLLENDEFRRAFLT--GVAATAGRSFRPAVTCFADVRARRLDALGDLVADHLD 484

Query: 473 VGAILDLLEHGAP 485
           +  +  LL+ GAP
Sbjct: 485 IATVRALLDRGAP 497


>tr|C9NHQ4|C9NHQ4_9ACTO Tax_Id=591167 (cobQ)RecName: Full=Cobyric
           acid synthase;[Streptomyces flavogriseus ATCC 33331]
          Length = 538

 Score =  436 bits (1120), Expect = e-120
 Identities = 246/490 (50%), Positives = 299/490 (61%), Gaps = 10/490 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G LLVAGTTSDAGKS++  G+CR LVR+G+ VAPFKAQNMS NS VT EG EI       
Sbjct: 3   GGLLVAGTTSDAGKSVVTAGICRWLVRRGVKVAPFKAQNMSLNSFVTREGAEIGRAQAMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDH-LAAVVADELSS 122
                  PS   NP+LLKPGGDR+SQ+V+ G+  G ++A  Y   R   L   V D L  
Sbjct: 63  AQAARVEPSALMNPVLLKPGGDRSSQVVLMGRPVGEMSARGYHGGRQEALLGTVTDCLEQ 122

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LR  +DAVICEGAGSPAEINLR TD+ NMG+ARAA  PV+VVGDIDRGG+ A   GT A+
Sbjct: 123 LRGTYDAVICEGAGSPAEINLRRTDIVNMGIARAARFPVLVVGDIDRGGVFASFFGTTAL 182

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           L P DQ+LV+G++VNKFRGD SLL PGL  L  LTGR T+GV+P+   + +D ED + V 
Sbjct: 183 LSPEDQSLVAGYLVNKFRGDVSLLEPGLDMLLGLTGRRTFGVLPYAHGLGIDEEDGLRVS 242

Query: 243 PGGLV--GAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
             G V      PP GE  L VA   +P +SN TD++ALA EPGVVVR+V  A +L  ADL
Sbjct: 243 MRGAVRESVVAPPHGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRAEELVDADL 302

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           V++PG++ TV  L WLRE                    CGGFQ+L  RI+D VESR GRV
Sbjct: 303 VIVPGTRGTVKALAWLRERGLADALLRRAAEGRPVLGICGGFQVLGERIEDDVESRAGRV 362

Query: 361 DGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYG 415
           +GLGLL   + F  +K L          P+ GYEIHHG    S    +L  G R G+V+G
Sbjct: 363 EGLGLLPVRVRFGREKVLARPVGTALGEPVEGYEIHHGVAEVSGGEPFLD-GCRVGSVWG 421

Query: 416 THWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGA 475
           THWHG L++DA RR +LTE                        QLD + DLIE H D  A
Sbjct: 422 THWHGSLESDAFRRAFLTE-VARAAGRRFAAAPDTSFGALREEQLDRLGDLIEEHADTDA 480

Query: 476 ILDLLEHGAP 485
           +  L+E GAP
Sbjct: 481 LWRLIETGAP 490


>tr|D3M1F1|D3M1F1_9ACTO Tax_Id=656024 (cobQ)RecName: Full=Cobyric
           acid synthase;[Frankia symbiont of Datisca glomerata]
          Length = 543

 Score =  435 bits (1119), Expect = e-120
 Identities = 258/535 (48%), Positives = 309/535 (57%), Gaps = 54/535 (10%)

Query: 1   MTGGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXX 60
           M+GGALLVAGTTSDAGKS++  GLCR L R+G+ VAPFKAQNM+ NS VT +G EI    
Sbjct: 1   MSGGALLVAGTTSDAGKSVVTAGLCRWLAREGVRVAPFKAQNMALNSVVTADGAEIGRAQ 60

Query: 61  XXXXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADEL 120
                     P    NP+LLKPG DR SQLVV G+    V A  Y  ++  LA +V D L
Sbjct: 61  AMQAAAAGVEPEAAMNPVLLKPGSDRHSQLVVLGRPVAEVDALGYRPYKARLAGIVTDCL 120

Query: 121 SSLREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTV 180
           + LR  FDAVICEGAGSPAEINLR TD+ANMGLARAA LPV+VVGDIDRGG+ A L GT+
Sbjct: 121 ADLRGRFDAVICEGAGSPAEINLRDTDIANMGLARAANLPVLVVGDIDRGGVFAALFGTL 180

Query: 181 AVLEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVS 240
           A+L+  DQALV+G++VNKFRGDP LL PGLRQL  LTGRP +GV+P+   +WLD EDS+ 
Sbjct: 181 ALLDAGDQALVAGWIVNKFRGDPRLLEPGLRQLERLTGRPVHGVLPWRSGLWLDVEDSLD 240

Query: 241 VRP------------------------GGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIE 276
           +                          GG  GA         L VA IRLPR+SN TDI+
Sbjct: 241 LASYPAYPDADGADTHGATDTGGADSRGGGTGATS--HTGDVLRVAVIRLPRLSNVTDID 298

Query: 277 ALACEPGVVVRWVTDAADLTGADLVVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXX 336
           AL  EPGV+V + T   DLT ADLVV+PG++ATV DL WLR                   
Sbjct: 299 ALRAEPGVLVGFATRPDDLTDADLVVVPGTRATVGDLGWLRRRGLDAALRARAARGRPLL 358

Query: 337 XXCGGFQMLCSRIDDPVESREGRVDGLGLLDADIEFAAQKTL--RHWETP----LHGYEI 390
             CGG+QML  RIDDPVES  G VDGLGLL     FA  K L  R   TP    + GYEI
Sbjct: 359 GICGGYQMLGRRIDDPVESGAGTVDGLGLLPVTTTFAPDKLLGRRTGTTPDGLTVTGYEI 418

Query: 391 HHGQV--------------------ARSAETDWLGIGLRRGAVYGTHWHGLLDNDALRRD 430
            HG++                       A   +   G+R GAV GT WHGLL+ND  RR+
Sbjct: 419 RHGRLTVHDTGPLARPAGGPVRGNAGGPAVEPFAADGVRAGAVAGTSWHGLLENDEFRRE 478

Query: 431 WLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAILDLLEHGAP 485
           +L +                        +LD++ DL+ +HLD  A+  LLE G P
Sbjct: 479 FLVD--VAARAGRSFTPARTCFADVRRRRLDILGDLVADHLDTAAVRRLLEGGPP 531


>tr|D3CYU2|D3CYU2_9ACTO Tax_Id=102897 SubName: Full=Cobyric acid
           synthase CobQ;[Frankia sp. EUN1f]
          Length = 525

 Score =  434 bits (1116), Expect = e-119
 Identities = 244/489 (49%), Positives = 297/489 (60%), Gaps = 13/489 (2%)

Query: 3   GGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXX 62
           G ALLVAGTTSDAGKS++  G+CR L R+G+ VAPFKAQNMS NS VT +G EI      
Sbjct: 12  GNALLVAGTTSDAGKSVVTAGICRFLARQGVRVAPFKAQNMSLNSWVTADGAEIGRAQVM 71

Query: 63  XXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSS 122
                   P    NP+LLKPG    SQ+V+RG+      A DY   +  L   V   L+ 
Sbjct: 72  QAAAAGIEPEAAMNPVLLKPGARHRSQVVLRGRPVAETGALDYRELKGRLFTEVLASLAD 131

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LR  FD V+CEGAGSPAEINLRA D+ANMGLARAA LP IVVGDIDRGG+ A ++GT+A+
Sbjct: 132 LRSRFDVVVCEGAGSPAEINLRANDIANMGLARAAGLPAIVVGDIDRGGVFAAMYGTLAL 191

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSV- 241
           LEPADQALV+GFVVNKFRG+ +LL PGL  L  LTGRP  GV+P+ D + LD EDS+ + 
Sbjct: 192 LEPADQALVAGFVVNKFRGERALLEPGLDMLRGLTGRPVLGVLPWQDGLDLDVEDSLGLP 251

Query: 242 RPGGLVGAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLV 301
            PG   G P  P     L VAA+RLP +SN TD++ALA EPGV VR+     DL  ADLV
Sbjct: 252 APGETRGDPAGP-----LRVAAVRLPFLSNFTDLDALAAEPGVAVRYADRPEDLDAADLV 306

Query: 302 VIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVD 361
           V+PG+++TV DL WLR                     CGG+QML + I D VESR G +D
Sbjct: 307 VLPGTRSTVADLGWLRRRGLHGALARRAASGRPVLGVCGGYQMLAATIVDEVESRVGAID 366

Query: 362 GLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGT 416
           GLGLL   + FAA KTL       +  P+ GYEIHHG         +L  G R GAV+GT
Sbjct: 367 GLGLLPVTVRFAADKTLGRPVGVAYGQPVRGYEIHHGVATVHGGEPFLD-GCRAGAVWGT 425

Query: 417 HWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAI 476
            WHG  +ND  RR +LT+                        +LD++ DL+ +HLD GA+
Sbjct: 426 TWHGAFENDGFRRAFLTD-VAARTGSPWQPRGEISFAAVRERRLDVLGDLVADHLDTGAL 484

Query: 477 LDLLEHGAP 485
             LL  G P
Sbjct: 485 RALLADGPP 493


>sp|Q8FP85|COBQ_COREF Tax_Id=152794 (cobQ)RecName: Full=Cobyric acid
           synthase;[Corynebacterium efficiens]
          Length = 493

 Score =  432 bits (1112), Expect = e-119
 Identities = 246/495 (49%), Positives = 295/495 (59%), Gaps = 11/495 (2%)

Query: 3   GGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXX 62
           G A L+AGTTSDAGKS++  GLCR   R GL VAPFKAQNMSNNSAVT +GGEI      
Sbjct: 4   GPAFLIAGTTSDAGKSVITAGLCRAFARAGLRVAPFKAQNMSNNSAVTSDGGEIGRAQAL 63

Query: 63  XXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSS 122
                   PSV FNPILLKPG D  ++LV+RG+  G V A DYI HR  L  + A +L S
Sbjct: 64  QALACGLEPSVEFNPILLKPGPDNRARLVIRGREQGDVGAGDYIRHRHDLRGIAAAQLES 123

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LRE FD V+CEGAGSPAEINLRATD+AN GLA+AA L V +VGDIDRGG+LAHL GT A+
Sbjct: 124 LRERFDIVVCEGAGSPAEINLRATDVANFGLAQAAQLAVYIVGDIDRGGVLAHLFGTHAI 183

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           +   D+AL+ GFV+NKFRG   LL PGL QL ELTG  T  VIPF D+IW+D EDS+   
Sbjct: 184 ISDEDRALIRGFVINKFRGHQELLEPGLVQLEELTGVETKAVIPFIDDIWIDAEDSLQSP 243

Query: 243 PGGLVG-APEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLV 301
            G +VG     P G Q L+VAAIRLPR+   TD+EALA EPGV V WV D   +  +DLV
Sbjct: 244 VGRMVGPGGRHPLGTQRLSVAAIRLPRMLGVTDVEALAVEPGVTVTWVDDVDAVWDSDLV 303

Query: 302 VIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVD 361
           +IPG+ ATV DL WLR                      GG+QM+ + I D  +S    V 
Sbjct: 304 IIPGTTATVADLAWLRHRGLDRALGERATRGMPILGIGGGYQMMATTITDEGDS-PSSVA 362

Query: 362 GLGLLDADIEFAAQKTLRHWETPLHG---YEIHHGQVARSAETDWL-GIGLRRGAVYGTH 417
           GL L D  I       + +     HG   YE+HHGQV    E  W+ G G RR A++GTH
Sbjct: 363 GLALFDVHIALTPHNIMVN-----HGDGSYEVHHGQVRHHGEQTWIEGEGARREALFGTH 417

Query: 418 WHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAIL 477
            HG L +D  RR +LTE                        QLD +AD++E H D+  +L
Sbjct: 418 RHGYLQDDPARRRFLTEVATHAGKPGFLVSPDTSFHGVRLQQLDRIADVLEEHWDLDQLL 477

Query: 478 DLLEHGAPHRPTMST 492
           D +   A    T  T
Sbjct: 478 DEVSRPANAANTPET 492


>tr|C8NPL1|C8NPL1_COREF Tax_Id=196164 (cobQ)SubName:
           Full=Adenosylcobyric acid synthase
           (Glutamine-hydrolyzing);[Corynebacterium efficiens
           YS-314]
          Length = 493

 Score =  432 bits (1112), Expect = e-119
 Identities = 246/495 (49%), Positives = 295/495 (59%), Gaps = 11/495 (2%)

Query: 3   GGALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXX 62
           G A L+AGTTSDAGKS++  GLCR   R GL VAPFKAQNMSNNSAVT +GGEI      
Sbjct: 4   GPAFLIAGTTSDAGKSVITAGLCRAFARAGLRVAPFKAQNMSNNSAVTSDGGEIGRAQAL 63

Query: 63  XXXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSS 122
                   PSV FNPILLKPG D  ++LV+RG+  G V A DYI HR  L  + A +L S
Sbjct: 64  QALACGLEPSVEFNPILLKPGPDNRARLVIRGREQGDVGAGDYIRHRHDLRGIAAAQLES 123

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LRE FD V+CEGAGSPAEINLRATD+AN GLA+AA L V +VGDIDRGG+LAHL GT A+
Sbjct: 124 LRERFDIVVCEGAGSPAEINLRATDVANFGLAQAAQLAVYIVGDIDRGGVLAHLFGTHAI 183

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           +   D+AL+ GFV+NKFRG   LL PGL QL ELTG  T  VIPF D+IW+D EDS+   
Sbjct: 184 ISDEDRALIRGFVINKFRGHQELLEPGLVQLEELTGVETKAVIPFIDDIWIDAEDSLQSP 243

Query: 243 PGGLVG-APEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLV 301
            G +VG     P G Q L+VAAIRLPR+   TD+EALA EPGV V WV D   +  +DLV
Sbjct: 244 VGRMVGPGGRHPLGTQRLSVAAIRLPRMLGVTDVEALAVEPGVTVTWVDDVDAVWDSDLV 303

Query: 302 VIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVD 361
           +IPG+ ATV DL WLR                      GG+QM+ + I D  +S    V 
Sbjct: 304 IIPGTTATVADLAWLRHRGLDRALGERATRGMPILGIGGGYQMMATTITDEGDS-PSSVA 362

Query: 362 GLGLLDADIEFAAQKTLRHWETPLHG---YEIHHGQVARSAETDWL-GIGLRRGAVYGTH 417
           GL L D  I       + +     HG   YE+HHGQV    E  W+ G G RR A++GTH
Sbjct: 363 GLALFDVHIALTPHNIMVN-----HGDGSYEVHHGQVRHHGEQTWIEGEGARREALFGTH 417

Query: 418 WHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAIL 477
            HG L +D  RR +LTE                        QLD +AD++E H D+  +L
Sbjct: 418 RHGYLQDDPARRRFLTEVATHAGKPGFLVSPDTSFHGVRLQQLDRIADVLEEHWDLDQLL 477

Query: 478 DLLEHGAPHRPTMST 492
           D +   A    T  T
Sbjct: 478 DEVSRPANAANTPET 492


>tr|D6ELH2|D6ELH2_STRLI Tax_Id=457428 SubName: Full=Cobyric acid
           synthase CobQ;[Streptomyces lividans TK24]
          Length = 502

 Score =  431 bits (1109), Expect = e-119
 Identities = 243/490 (49%), Positives = 298/490 (60%), Gaps = 10/490 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G LLVAGTTSDAGKS++  G+CR LVR+G+ VAPFKAQNMS NS VT +G EI       
Sbjct: 3   GGLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTRDGAEIGRAQAMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHR-DHLAAVVADELSS 122
                  P+   NP+LLKPGG+R+SQ+V+ G+  G ++A  Y   R + L   V D L+ 
Sbjct: 63  AQACRVEPTAHMNPVLLKPGGERSSQVVLLGRPVGEMSARGYHGGRQERLLGTVLDSLAE 122

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LR  +DAVICEGAGSPAEINLR TD+ NMG+AR A LPV+VVGDIDRGG+ A   GTVA+
Sbjct: 123 LRGTYDAVICEGAGSPAEINLRRTDIVNMGIARGAGLPVLVVGDIDRGGVFASFFGTVAL 182

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           L P DQALV+GF+VNKFRGD SLL PGL  L  LTGR TYGV+PF   + +D ED + V 
Sbjct: 183 LAPEDQALVAGFLVNKFRGDVSLLEPGLDMLHGLTGRRTYGVLPFRHGLGIDEEDGLRVS 242

Query: 243 PGGLV--GAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
             G V   A  PP GE  L VA   +P +SN TD++ALA EPGVVVR+V    +L  ADL
Sbjct: 243 LRGTVRESAVAPPVGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRPEELADADL 302

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           V++PG++ TV  L WLRE                    CGG+Q+L   I+D VESR G V
Sbjct: 303 VIVPGTRGTVRALEWLRERGLADAIARRATERRPVLGICGGYQLLGEHIEDEVESRAGHV 362

Query: 361 DGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYG 415
           DGLGLL   + F  +KTL          P+ GYEIHHG    +    +L  G R G  +G
Sbjct: 363 DGLGLLPVRVRFDREKTLTRPVGEALGEPVEGYEIHHGVAEVTGGAPFLD-GCRVGRTWG 421

Query: 416 THWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGA 475
           THWHG L++D  RR +L E                        QLD + DLIE+H D  A
Sbjct: 422 THWHGSLESDGFRRAFLRE-VAAAAGRRFVPAPDTSFAALREEQLDRLGDLIEHHADTDA 480

Query: 476 ILDLLEHGAP 485
           +  L+E GAP
Sbjct: 481 LWRLIESGAP 490


>tr|D1VGL0|D1VGL0_9ACTO Tax_Id=298654 (cobQ)RecName: Full=Cobyric
           acid synthase;[Frankia sp. EuI1c]
          Length = 532

 Score =  430 bits (1106), Expect = e-118
 Identities = 248/489 (50%), Positives = 298/489 (60%), Gaps = 15/489 (3%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           GALLVAGTTSDAGKS+L  G+CR L R+G+ VAPFKAQNMS NS VT +G EI       
Sbjct: 3   GALLVAGTTSDAGKSVLTAGICRWLARQGVRVAPFKAQNMSLNSWVTADGAEIGRAQVMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDHLAAVVADELSSL 123
                  P    NP+LLKPG    SQ+V+RG+      A DY   +  L   V   L+ L
Sbjct: 63  AAAAGVEPEGAMNPVLLKPGAGHRSQVVLRGRPVAEAGALDYRALKGRLFTEVLASLADL 122

Query: 124 REDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAVL 183
           R  FD VICEGAGSPAEINLRA D+ANMGLARAA LP +VVGDIDRGG+ A + GT+A+L
Sbjct: 123 RSRFDVVICEGAGSPAEINLRADDIANMGLARAARLPTLVVGDIDRGGVFAAMFGTLALL 182

Query: 184 EPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVRP 243
           EPADQALV+GFVVNKFRG+ +LL PGL  L+ LTGRP  GV+P+ D + LD EDS+ + P
Sbjct: 183 EPADQALVAGFVVNKFRGERALLEPGLGMLSGLTGRPVLGVLPWRDGLGLDVEDSLGL-P 241

Query: 244 GGLVGAPEPPRG--EQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADLV 301
           G     P   RG  + TL VAA+RLP +SN TD++ALA EPGV VR+V    DL  ADLV
Sbjct: 242 G-----PGETRGDLDGTLRVAAVRLPFLSNFTDLDALAAEPGVAVRYVDRPEDLDAADLV 296

Query: 302 VIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRVD 361
           V+PG+++TV DL WLR                     CGG+QML   I D VES  GRVD
Sbjct: 297 VLPGTRSTVADLAWLRGRRLDGPLARRAATGRPVLGVCGGYQMLAETIVDEVESGAGRVD 356

Query: 362 GLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYGT 416
           GLGLL   I FAA KTL       +  P+ GYEIHHG  +      +L  G R GAV+GT
Sbjct: 357 GLGLLPVTIRFAAAKTLGRPDGVAYGQPVRGYEIHHGVASVHGGEPFLD-GCRAGAVWGT 415

Query: 417 HWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGAI 476
            WHG  +ND  RR +L +                        +LD++ DL+  HLD  A+
Sbjct: 416 TWHGAFENDGFRRAFLAD-VAARVGSPWQPRGEVSFAAVRERRLDVLGDLVAEHLDTDAL 474

Query: 477 LDLLEHGAP 485
           L LL  G P
Sbjct: 475 LRLLADGPP 483


>sp|Q9RJ20|COBQ_STRCO Tax_Id=1902 (cobQ)RecName: Full=Cobyric acid
           synthase;[Streptomyces coelicolor]
          Length = 502

 Score =  430 bits (1105), Expect = e-118
 Identities = 242/490 (49%), Positives = 297/490 (60%), Gaps = 10/490 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G LLVAGTTSDAGKS++  G+CR LVR+G+ VAPFKAQNMS NS VT +G EI       
Sbjct: 3   GGLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTRDGAEIGRAQAMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHR-DHLAAVVADELSS 122
                  P+   NP+LLKPGG+R+SQ+V+ G+  G ++A  Y   R + L   V D L+ 
Sbjct: 63  AQACRVEPTAHMNPVLLKPGGERSSQVVLLGRPVGEMSARGYHGGRQERLLGTVLDSLAE 122

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LR  +DAVICEGAGSPAEINLR TD+ NMG+AR A LPV+VVGDIDRGG+ A   GTVA+
Sbjct: 123 LRGTYDAVICEGAGSPAEINLRRTDIVNMGIARGAGLPVLVVGDIDRGGVFASFFGTVAL 182

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           L P DQALV+GF+VNKFRGD SLL PGL  L  LTGR TYGV+PF   + +D ED + V 
Sbjct: 183 LAPEDQALVAGFLVNKFRGDVSLLEPGLDMLHGLTGRRTYGVLPFRHGLGIDEEDGLRVS 242

Query: 243 PGGLV--GAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
             G V      PP GE  L VA   +P +SN TD++ALA EPGVVVR+V    +L  ADL
Sbjct: 243 LRGTVRESVVAPPVGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRPEELADADL 302

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           V++PG++ TV  L WLRE                    CGG+Q+L   I+D VESR G V
Sbjct: 303 VIVPGTRGTVRALEWLRERGLADAIARRAAERRPVLGICGGYQLLGEHIEDEVESRAGHV 362

Query: 361 DGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYG 415
           DGLGLL   + F  +KTL          P+ GYEIHHG    +    +L  G R G  +G
Sbjct: 363 DGLGLLPVRVRFDREKTLTRAVGEALGEPVEGYEIHHGVAEVTGGAPFLD-GCRVGRTWG 421

Query: 416 THWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGA 475
           THWHG L++D  RR +L E                        QLD + DLIE+H D  A
Sbjct: 422 THWHGSLESDGFRRAFLRE-VAAAAGRRFVPAPDTSFAALREEQLDRLGDLIEHHADTDA 480

Query: 476 ILDLLEHGAP 485
           +  L+E GAP
Sbjct: 481 LWRLIESGAP 490


>tr|D6K9W1|D6K9W1_9ACTO Tax_Id=645465 SubName: Full=Cobyric acid
           synthase CobQ;[Streptomyces sp. e14]
          Length = 502

 Score =  427 bits (1098), Expect = e-117
 Identities = 245/490 (50%), Positives = 296/490 (60%), Gaps = 10/490 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G LLVAGTTSDAGKS++  G+CR LVR+G+ VAPFKAQNMS NS VT EG EI       
Sbjct: 3   GGLLVAGTTSDAGKSVVTAGICRWLVRQGVKVAPFKAQNMSLNSFVTREGAEIGRAQAMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDH-LAAVVADELSS 122
                  P+   NP+LLKPGG+++SQ+V+ G+  G ++A  Y   R   L   V D L+ 
Sbjct: 63  AQACRIEPTALMNPVLLKPGGEQSSQVVLLGKPVGELSARGYHGGRQQKLLGTVLDCLAE 122

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LR  +DAVICEGAGSPAEINLR TD+ NMG+AR A LPV+VVGDIDRGG+ A   GT+A+
Sbjct: 123 LRGTYDAVICEGAGSPAEINLRRTDIVNMGIARGARLPVLVVGDIDRGGVFASFFGTLAL 182

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           L P DQ LV+GF+VNKFRGD SLL PGL  L  LTGR TYGV+PF   + +D ED + V 
Sbjct: 183 LSPEDQELVAGFLVNKFRGDVSLLEPGLDMLHGLTGRHTYGVLPFRHGLGIDEEDGLRVS 242

Query: 243 PGGLV--GAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
             G V       P GE  L VA   +P +SN TD++ALA EPGVVVR+V    +L  ADL
Sbjct: 243 LRGAVRESVVAAPVGEDVLRVAVCAIPLMSNFTDVDALAAEPGVVVRFVDRPEELADADL 302

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           VV+PG++ TV  LRWLRE                    CGGFQ+L  RI+D VESR G V
Sbjct: 303 VVVPGTRGTVRALRWLRERGLADALVRRAAEGRPVLGVCGGFQILGERIEDDVESRAGAV 362

Query: 361 DGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYG 415
            GLGLL   + FA +KTL          P+ GYEIHHG         +L  G R GAV+G
Sbjct: 363 AGLGLLPVRVRFAREKTLTRPSGHALGEPVEGYEIHHGVATVEGGEPFLD-GCRVGAVWG 421

Query: 416 THWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGA 475
           THWHG L++D  RR +L E                        QLD + DLIE H D  A
Sbjct: 422 THWHGSLESDGFRRAFLRE-VAAAAGRRFTPAPDTSFAALREEQLDRLGDLIEQHADTDA 480

Query: 476 ILDLLEHGAP 485
           +  L+E GAP
Sbjct: 481 LWRLIESGAP 490


>tr|B1W1S6|B1W1S6_STRGG Tax_Id=455632 SubName: Full=Putative cobyric
           acid synthase;[Streptomyces griseus subsp. griseus]
          Length = 554

 Score =  426 bits (1095), Expect = e-117
 Identities = 242/490 (49%), Positives = 296/490 (60%), Gaps = 10/490 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G LLVAGTTSDAGKS++  G+CR LVR+G+ VAPFKAQNMS NS VT +G EI       
Sbjct: 3   GGLLVAGTTSDAGKSVVTAGICRWLVRRGVKVAPFKAQNMSLNSFVTRQGAEIGRAQAMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDH-LAAVVADELSS 122
                  P+   NP+LLKPG DR+SQ+V+ G+  G ++A  Y   R   L   V + L  
Sbjct: 63  AQAARVEPTALMNPVLLKPGSDRSSQVVLMGKPVGEMSARGYHGGRQEALLGTVTECLEQ 122

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LR ++DAVICEGAGSPAEINLR TD+ NMG+ARAA  PV+VVGDIDRGG+ A   GT A+
Sbjct: 123 LRSEYDAVICEGAGSPAEINLRRTDIVNMGIARAARFPVLVVGDIDRGGVFASFFGTTAL 182

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           L P DQ+LV+G++VNKFRGD SLL PGL  L  LTGR TYGV+P+   + +D ED + V 
Sbjct: 183 LGPEDQSLVAGYLVNKFRGDVSLLEPGLDMLYGLTGRRTYGVLPYAHGLGIDEEDGLRVS 242

Query: 243 PGGLV--GAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
             G V      PP GE  L VA   +P +SN TD++ALA EPGVVVR+V  A +L  ADL
Sbjct: 243 LRGAVRESVVAPPHGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRAEELADADL 302

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           V++PG++ TV  L WLRE                    CGGFQ+L  RI+D VESR G V
Sbjct: 303 VIVPGTRGTVKALAWLRERGLAQALVRRAAEGRPVLGICGGFQVLGERIEDEVESRAGVV 362

Query: 361 DGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYG 415
           DGLG+L   I F   KTL          P+ GYEIHHG         +L  G R GAV+G
Sbjct: 363 DGLGVLPVRIRFDRDKTLARPVGSALGEPVEGYEIHHGVADVRGGEPFLD-GCRVGAVWG 421

Query: 416 THWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGA 475
           THWHG L++DA RR +L E                        QLD + DL+E H D  A
Sbjct: 422 THWHGSLESDAFRRRFLVE-VARAAGRRFVPAPDTSFGELREEQLDRLGDLVEEHADTDA 480

Query: 476 ILDLLEHGAP 485
           +  L+E GAP
Sbjct: 481 LWRLIEGGAP 490


>tr|D1XFS0|D1XFS0_9ACTO Tax_Id=647653 SubName: Full=Cobyric acid
           synthase CobQ;[Streptomyces sp. ACTE]
          Length = 559

 Score =  425 bits (1093), Expect = e-117
 Identities = 244/490 (49%), Positives = 295/490 (60%), Gaps = 10/490 (2%)

Query: 4   GALLVAGTTSDAGKSMLVGGLCRLLVRKGLSVAPFKAQNMSNNSAVTVEGGEIXXXXXXX 63
           G LLVAGTTSDAGKS++  G+CR LVR+G+ VAPFKAQNMS NS VT EG EI       
Sbjct: 3   GGLLVAGTTSDAGKSVVTAGICRWLVRQGVRVAPFKAQNMSLNSFVTREGAEIGRAQAMQ 62

Query: 64  XXXXXXXPSVRFNPILLKPGGDRTSQLVVRGQVTGSVAAADYINHRDH-LAAVVADELSS 122
                  P+   NP+LLKPGGDR+SQ+V+ G+  G ++A  Y   R   L   V D L  
Sbjct: 63  AQAARVEPTALMNPVLLKPGGDRSSQVVLMGRPVGEMSARGYHGGRQEALFGTVVDCLEQ 122

Query: 123 LREDFDAVICEGAGSPAEINLRATDLANMGLARAAALPVIVVGDIDRGGLLAHLHGTVAV 182
           LR  +DAVICEGAGSPAEINLR TD+ NMG+ARAA  PV+VVGDIDRGG+ A   GT A+
Sbjct: 123 LRGAYDAVICEGAGSPAEINLRRTDIVNMGVARAAGFPVLVVGDIDRGGVFASFFGTTAL 182

Query: 183 LEPADQALVSGFVVNKFRGDPSLLAPGLRQLAELTGRPTYGVIPFHDEIWLDTEDSVSVR 242
           L   DQ+LV+G++VNKFRGD SLL PGL  L  LTGR TYGV+P+   + +D ED + V 
Sbjct: 183 LSAEDQSLVAGYLVNKFRGDVSLLEPGLDMLHGLTGRRTYGVLPYAHGLGIDEEDGLRVS 242

Query: 243 PGGLV--GAPEPPRGEQTLTVAAIRLPRISNSTDIEALACEPGVVVRWVTDAADLTGADL 300
             G V      PP GE  L VA   +P +SN TD++ALA EPGVVVR+V  A +L+ ADL
Sbjct: 243 MRGTVRESVVAPPHGEDVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRAEELSDADL 302

Query: 301 VVIPGSKATVTDLRWLREXXXXXXXXXXXXXXXXXXXXCGGFQMLCSRIDDPVESREGRV 360
           VV+PG++ TV  L WLRE                    CGGFQ+L   IDD VESR G V
Sbjct: 303 VVVPGTRGTVRALAWLRERGLADALRRRAAEGRPVLGVCGGFQVLGESIDDEVESRAGLV 362

Query: 361 DGLGLLDADIEFAAQKTLRH-----WETPLHGYEIHHGQVARSAETDWLGIGLRRGAVYG 415
           +GLGLL   + F  +K L          P+ GYEIHHG         +L  G R GAV+G
Sbjct: 363 EGLGLLPVRVRFGREKVLARPTGSALGEPVEGYEIHHGVAEVRGGEPFLD-GCRVGAVWG 421

Query: 416 THWHGLLDNDALRRDWLTEXXXXXXXXXXXXXXXXXXXXXXXXQLDLMADLIENHLDVGA 475
           THWHG L++DA RR +L E                        QLD + DLIE H D  A
Sbjct: 422 THWHGSLESDAFRRAFLGE-VARASGRRFTAAPDTSFAALREEQLDRLGDLIEEHADTDA 480

Query: 476 ILDLLEHGAP 485
           +  L+E GAP
Sbjct: 481 LWRLIESGAP 490


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.319    0.137    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 3,818,562,697
Number of extensions: 151335154
Number of successful extensions: 350023
Number of sequences better than 10.0: 1216
Number of HSP's gapped: 346845
Number of HSP's successfully gapped: 1224
Length of query: 496
Length of database: 4,236,830,644
Length adjustment: 142
Effective length of query: 354
Effective length of database: 2,460,713,956
Effective search space: 871092740424
Effective search space used: 871092740424
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 83 (36.6 bits)