BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_2617 (458 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|A0QVL6|A0QVL6_MYCS2 Tax_Id=246196 (cobB)SubName: Full=Cobyrin... 862 0.0 tr|Q1BAA3|Q1BAA3_MYCSS Tax_Id=164756 SubName: Full=Hydrogenobyri... 645 0.0 tr|A3PY66|A3PY66_MYCSJ Tax_Id=164757 SubName: Full=Hydrogenobyri... 645 0.0 tr|A1UEQ9|A1UEQ9_MYCSK Tax_Id=189918 SubName: Full=Hydrogenobyri... 645 0.0 tr|A1T7G8|A1T7G8_MYCVP Tax_Id=350058 SubName: Full=Cobyrinate a,... 642 0.0 tr|A4TCF0|A4TCF0_MYCGI Tax_Id=350054 SubName: Full=Hydrogenobyri... 629 e-178 tr|A0QIZ3|A0QIZ3_MYCA1 Tax_Id=243243 (cobB)SubName: Full=Cobyrin... 621 e-176 sp|P63835|COBB_MYCTU Tax_Id=1773 (cobB)RecName: Full=Cobyrinic a... 618 e-175 sp|P63836|COBB_MYCBO Tax_Id=1765 (cobB)RecName: Full=Cobyrinic a... 618 e-175 tr|C6DWZ3|C6DWZ3_MYCTK Tax_Id=478434 SubName: Full=Cobyrinic aci... 618 e-175 tr|C1AFW2|C1AFW2_MYCBT Tax_Id=561275 (cobB)SubName: Full=Cobyrin... 618 e-175 tr|A5WRA1|A5WRA1_MYCTF Tax_Id=336982 SubName: Full=Cobyrinic aci... 618 e-175 tr|A5U6K0|A5U6K0_MYCTA Tax_Id=419947 (cobB)SubName: Full=Cobyrin... 618 e-175 tr|A1KMJ1|A1KMJ1_MYCBP Tax_Id=410289 (cobB)SubName: Full=Probabl... 618 e-175 tr|D6G2B3|D6G2B3_MYCTU Tax_Id=478435 SubName: Full=Cobyrinic aci... 618 e-175 tr|D6FNQ8|D6FNQ8_MYCTU Tax_Id=611304 SubName: Full=Cobyrinic aci... 618 e-175 tr|D6FK78|D6FK78_MYCTU Tax_Id=611303 SubName: Full=Cobyrinic aci... 618 e-175 tr|D6F7X3|D6F7X3_MYCTU Tax_Id=611302 SubName: Full=Cobyrinic aci... 618 e-175 tr|D5ZK38|D5ZK38_MYCTU Tax_Id=537210 SubName: Full=Cobyrinic aci... 618 e-175 tr|D5Z731|D5Z731_MYCTU Tax_Id=537209 SubName: Full=Cobyrinic aci... 618 e-175 tr|D5YIF1|D5YIF1_MYCTU Tax_Id=520140 SubName: Full=Cobyrinic aci... 618 e-175 tr|D5XXI6|D5XXI6_MYCTU Tax_Id=515617 SubName: Full=Cobyrinic aci... 618 e-175 tr|A4KKB6|A4KKB6_MYCTU Tax_Id=395095 SubName: Full=Cobyrinic aci... 618 e-175 tr|A2VLI1|A2VLI1_MYCTU Tax_Id=348776 SubName: Full=Cobyrinic aci... 618 e-175 tr|Q73VU4|Q73VU4_MYCPA Tax_Id=1770 (cobB)RecName: Full=Cobyrinic... 617 e-174 tr|D5PJC9|D5PJC9_9MYCO Tax_Id=525368 (cobB)SubName: Full=Cobyrin... 613 e-173 tr|D5YVD0|D5YVD0_MYCTU Tax_Id=515616 SubName: Full=Cobyrinic aci... 608 e-172 tr|B2HKR3|B2HKR3_MYCMM Tax_Id=216594 (cobB)SubName: Full=Cobyrin... 607 e-172 tr|A0PQB5|A0PQB5_MYCUA Tax_Id=362242 (cobB)SubName: Full=Cobyrin... 606 e-171 tr|Q0S247|Q0S247_RHOSR Tax_Id=101510 (cobB)SubName: Full=Cobyrin... 542 e-152 tr|D5Y6T6|D5Y6T6_MYCTU Tax_Id=520141 SubName: Full=Cobyrinic aci... 534 e-149 tr|C1B2Y1|C1B2Y1_RHOOB Tax_Id=632772 (cobB)SubName: Full=Cobyrin... 533 e-149 tr|D5PMW5|D5PMW5_COREQ Tax_Id=525370 (cobB)SubName: Full=Cobyrin... 526 e-147 tr|Q5YSB1|Q5YSB1_NOCFA Tax_Id=37329 (cobB)SubName: Full=Putative... 522 e-146 tr|C0ZY81|C0ZY81_RHOE4 Tax_Id=234621 (cobB)SubName: Full=Cobyrin... 521 e-146 tr|B1MDB1|B1MDB1_MYCA9 Tax_Id=561007 SubName: Full=Probable coby... 521 e-145 tr|C3JM31|C3JM31_RHOER Tax_Id=596309 (cobB)SubName: Full=Cobyrin... 517 e-144 tr|C6WEP3|C6WEP3_ACTMD Tax_Id=446462 SubName: Full=Cobyrinic aci... 494 e-137 tr|D5UM40|D5UM40_TSUPA Tax_Id=521096 SubName: Full=Cobyrinic aci... 487 e-135 tr|A4FM70|A4FM70_SACEN Tax_Id=405948 (cobB)SubName: Full=Cobyrin... 480 e-133 tr|D0LBH1|D0LBH1_GORB4 Tax_Id=526226 SubName: Full=Cobyrinic aci... 477 e-132 tr|B1W1S3|B1W1S3_STRGG Tax_Id=455632 SubName: Full=Putative coby... 447 e-123 tr|D1WX34|D1WX34_9ACTO Tax_Id=649189 SubName: Full=Cobyrinic aci... 447 e-123 tr|D6APA3|D6APA3_STRFL Tax_Id=457431 SubName: Full=Cobyrinic aci... 439 e-121 tr|D1XFS3|D1XFS3_9ACTO Tax_Id=647653 SubName: Full=Cobyrinic aci... 432 e-119 >tr|A0QVL6|A0QVL6_MYCS2 Tax_Id=246196 (cobB)SubName: Full=Cobyrinic Acid a,c-diamide synthase; EC=6.3.1.-;[Mycobacterium smegmatis] Length = 458 Score = 862 bits (2226), Expect = 0.0 Identities = 440/458 (96%), Positives = 440/458 (96%) Query: 1 MVGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPG 60 MVGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPG Sbjct: 1 MVGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPG 60 Query: 61 RNLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLG 120 RNLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLG Sbjct: 61 RNLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLG 120 Query: 121 APVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAV 180 APVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAV Sbjct: 121 APVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAV 180 Query: 181 LGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQ 240 LGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQ Sbjct: 181 LGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQ 240 Query: 241 PWSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGA 300 PWSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGA Sbjct: 241 PWSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGA 300 Query: 301 DALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVL 360 DALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVL Sbjct: 301 DALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVL 360 Query: 361 RGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXX 420 RGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDL Sbjct: 361 RGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLPPAWAFAGRGGA 420 Query: 421 XXXXXXVLRGVHAGYLHTHPAAHPQAIARFVASAVPTN 458 VLRGVHAGYLHTHPAAHPQAIARFVASAVPTN Sbjct: 421 PARDGAVLRGVHAGYLHTHPAAHPQAIARFVASAVPTN 458 >tr|Q1BAA3|Q1BAA3_MYCSS Tax_Id=164756 SubName: Full=Hydrogenobyrinic acid a,c-diamide synthase (Glutamine-hydrolysing) / cobyrinate a,c-diamide synthase; EC=6.3.5.-; EC=6.3.5.9;[Mycobacterium sp.] Length = 454 Score = 645 bits (1663), Expect = 0.0 Identities = 327/449 (72%), Positives = 359/449 (79%), Gaps = 4/449 (0%) Query: 6 PAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDP 65 PAVV+AAPASGSGKTTV+TGL+GALR AGH VAPFKVGPDFIDPGYHA+AAGRPGRNLDP Sbjct: 3 PAVVVAAPASGSGKTTVATGLMGALRRAGHVVAPFKVGPDFIDPGYHALAAGRPGRNLDP 62 Query: 66 VLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVIL 125 VLVGE LIG LYAHG+AGADIAVVEGVMGLFDGRI DQM+G GS A VA+LLGAPV+L Sbjct: 63 VLVGEHLIGALYAHGTAGADIAVVEGVMGLFDGRIADQMSGPATGSTAHVAALLGAPVVL 122 Query: 126 VVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIP 185 VVDARGQS SIAALLHGF+TFD +AGV+LNRVGSPRHE VLRQACEHAG+ V G+IP Sbjct: 123 VVDARGQSHSIAALLHGFSTFDPQTRIAGVVLNRVGSPRHEEVLRQACEHAGLPVFGSIP 182 Query: 186 RADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPC 245 R + LSVPSRHLGL+TAVEHGR ARDA+ AMT+L+ RHVDL AV+A A A V+ PW P Sbjct: 183 RTEALSVPSRHLGLVTAVEHGRAARDAITAMTDLIARHVDLDAVVAHARATVTDAPWDPG 242 Query: 246 VETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVL 305 V P GVTVALA+GKAF+FGY EH ELLR GA V EFDP+ D LP ALV+ Sbjct: 243 V----PDPAAPGVTVALAAGKAFTFGYPEHGELLRAAGAEVVEFDPMTDELPADTSALVI 298 Query: 306 PGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAK 365 PGGFPEQ A+LSAN VRQQI++LA GAPIHAECAGLTYLVDDLDG PMCGVL G+A+ Sbjct: 299 PGGFPEQHAADLSANAPVRQQIAQLAALGAPIHAECAGLTYLVDDLDGRPMCGVLSGAAR 358 Query: 366 FTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXX 425 FTERLTLGYR A+A+ DS +H AGERV GHEFHRT VTF Sbjct: 359 FTERLTLGYRQAIAITDSPLHRAGERVTGHEFHRTAVTFSHRYEAAWHFGGGSTGTVADG 418 Query: 426 XVLRGVHAGYLHTHPAAHPQAIARFVASA 454 V RGVHAGYLHTHPAAHP AIARFVASA Sbjct: 419 AVHRGVHAGYLHTHPAAHPDAIARFVASA 447 >tr|A3PY66|A3PY66_MYCSJ Tax_Id=164757 SubName: Full=Hydrogenobyrinic acid a,c-diamide synthase (Glutamine-hydrolysing) / cobyrinate a,c-diamide synthase; EC=6.3.5.-; EC=6.3.5.9;[Mycobacterium sp.] Length = 455 Score = 645 bits (1663), Expect = 0.0 Identities = 327/449 (72%), Positives = 359/449 (79%), Gaps = 4/449 (0%) Query: 6 PAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDP 65 PAVV+AAPASGSGKTTV+TGL+GALR AGH VAPFKVGPDFIDPGYHA+AAGRPGRNLDP Sbjct: 4 PAVVVAAPASGSGKTTVATGLMGALRRAGHVVAPFKVGPDFIDPGYHALAAGRPGRNLDP 63 Query: 66 VLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVIL 125 VLVGE LIG LYAHG+AGADIAVVEGVMGLFDGRI DQM+G GS A VA+LLGAPV+L Sbjct: 64 VLVGEHLIGALYAHGTAGADIAVVEGVMGLFDGRIADQMSGPATGSTAHVAALLGAPVVL 123 Query: 126 VVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIP 185 VVDARGQS SIAALLHGF+TFD +AGV+LNRVGSPRHE VLRQACEHAG+ V G+IP Sbjct: 124 VVDARGQSHSIAALLHGFSTFDPQTRIAGVVLNRVGSPRHEEVLRQACEHAGLPVFGSIP 183 Query: 186 RADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPC 245 R + LSVPSRHLGL+TAVEHGR ARDA+ AMT+L+ RHVDL AV+A A A V+ PW P Sbjct: 184 RTEALSVPSRHLGLVTAVEHGRAARDAITAMTDLIARHVDLDAVVAHARATVTDAPWDPG 243 Query: 246 VETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVL 305 V P GVTVALA+GKAF+FGY EH ELLR GA V EFDP+ D LP ALV+ Sbjct: 244 V----PDPAAPGVTVALAAGKAFTFGYPEHGELLRAAGAEVVEFDPMTDELPADTSALVI 299 Query: 306 PGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAK 365 PGGFPEQ A+LSAN VRQQI++LA GAPIHAECAGLTYLVDDLDG PMCGVL G+A+ Sbjct: 300 PGGFPEQHAADLSANAPVRQQIAQLAALGAPIHAECAGLTYLVDDLDGRPMCGVLSGAAR 359 Query: 366 FTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXX 425 FTERLTLGYR A+A+ DS +H AGERV GHEFHRT VTF Sbjct: 360 FTERLTLGYRQAIAITDSPLHRAGERVTGHEFHRTAVTFSHRYEAAWHFGGGSTGTVADG 419 Query: 426 XVLRGVHAGYLHTHPAAHPQAIARFVASA 454 V RGVHAGYLHTHPAAHP AIARFVASA Sbjct: 420 AVHRGVHAGYLHTHPAAHPDAIARFVASA 448 >tr|A1UEQ9|A1UEQ9_MYCSK Tax_Id=189918 SubName: Full=Hydrogenobyrinic acid a,c-diamide synthase (Glutamine-hydrolysing) / cobyrinate a,c-diamide synthase; EC=6.3.5.-; EC=6.3.5.9;[Mycobacterium sp.] Length = 455 Score = 645 bits (1663), Expect = 0.0 Identities = 327/449 (72%), Positives = 359/449 (79%), Gaps = 4/449 (0%) Query: 6 PAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDP 65 PAVV+AAPASGSGKTTV+TGL+GALR AGH VAPFKVGPDFIDPGYHA+AAGRPGRNLDP Sbjct: 4 PAVVVAAPASGSGKTTVATGLMGALRRAGHVVAPFKVGPDFIDPGYHALAAGRPGRNLDP 63 Query: 66 VLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVIL 125 VLVGE LIG LYAHG+AGADIAVVEGVMGLFDGRI DQM+G GS A VA+LLGAPV+L Sbjct: 64 VLVGEHLIGALYAHGTAGADIAVVEGVMGLFDGRIADQMSGPATGSTAHVAALLGAPVVL 123 Query: 126 VVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIP 185 VVDARGQS SIAALLHGF+TFD +AGV+LNRVGSPRHE VLRQACEHAG+ V G+IP Sbjct: 124 VVDARGQSHSIAALLHGFSTFDPQTRIAGVVLNRVGSPRHEEVLRQACEHAGLPVFGSIP 183 Query: 186 RADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPC 245 R + LSVPSRHLGL+TAVEHGR ARDA+ AMT+L+ RHVDL AV+A A A V+ PW P Sbjct: 184 RTEALSVPSRHLGLVTAVEHGRAARDAITAMTDLIARHVDLDAVVAHARATVTDAPWDPG 243 Query: 246 VETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVL 305 V P GVTVALA+GKAF+FGY EH ELLR GA V EFDP+ D LP ALV+ Sbjct: 244 V----PDPAAPGVTVALAAGKAFTFGYPEHGELLRAAGAEVVEFDPMTDELPADTSALVI 299 Query: 306 PGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAK 365 PGGFPEQ A+LSAN VRQQI++LA GAPIHAECAGLTYLVDDLDG PMCGVL G+A+ Sbjct: 300 PGGFPEQHAADLSANAPVRQQIAQLAALGAPIHAECAGLTYLVDDLDGRPMCGVLSGAAR 359 Query: 366 FTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXX 425 FTERLTLGYR A+A+ DS +H AGERV GHEFHRT VTF Sbjct: 360 FTERLTLGYRQAIAITDSPLHRAGERVTGHEFHRTAVTFSHRYEAAWHFGGGSTGTVADG 419 Query: 426 XVLRGVHAGYLHTHPAAHPQAIARFVASA 454 V RGVHAGYLHTHPAAHP AIARFVASA Sbjct: 420 AVHRGVHAGYLHTHPAAHPDAIARFVASA 448 >tr|A1T7G8|A1T7G8_MYCVP Tax_Id=350058 SubName: Full=Cobyrinate a,c-diamide synthase / hydrogenobyrinic acid a,c-diamide synthase (Glutamine-hydrolysing); EC=6.3.5.-; EC=6.3.5.9;[Mycobacterium vanbaalenii] Length = 460 Score = 642 bits (1657), Expect = 0.0 Identities = 335/454 (73%), Positives = 362/454 (79%), Gaps = 5/454 (1%) Query: 4 TTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNL 63 +TPAVVIAAPASGSGKTTV+TGL+GALR AGH VAPFKVGPDFIDPGYHA+A RPGRNL Sbjct: 8 STPAVVIAAPASGSGKTTVATGLMGALRLAGHRVAPFKVGPDFIDPGYHALATARPGRNL 67 Query: 64 DPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPV 123 DPVLVGE LIGPLY HGS ADIAVVEGVMGLFDGRI D G QGS A VASLLGAPV Sbjct: 68 DPVLVGESLIGPLYRHGSDDADIAVVEGVMGLFDGRISDAAVGPAQGSTAHVASLLGAPV 127 Query: 124 ILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGA 183 +LVVDARGQS S+AALLHGF TFDS+V +AGVILNRVGS RHE VLRQACE AG VLG+ Sbjct: 128 VLVVDARGQSHSVAALLHGFATFDSSVRLAGVILNRVGSARHEQVLRQACEQAGAVVLGS 187 Query: 184 IPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWS 243 IPRADEL+VPSRHLGL+TAVEHGR+A AV AMTELV RHVDLAAV + AS+RV PW+ Sbjct: 188 IPRADELAVPSRHLGLVTAVEHGRRATAAVQAMTELVARHVDLAAVASVASSRVDDAPWT 247 Query: 244 PCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADAL 303 P TS A VTVALA+G+AFSFGYAEH ELL +GA V EFDPL DPLP A AL Sbjct: 248 PPPRTS-----PARVTVALAAGRAFSFGYAEHRELLCASGADVVEFDPLCDPLPPDAAAL 302 Query: 304 VLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGS 363 VLPGGFPE+F ELSAN++VR+QI LA GAP+ AECAGLTYLVDDLDG PMCGVL GS Sbjct: 303 VLPGGFPEEFGTELSANEVVREQIRALAAGGAPVQAECAGLTYLVDDLDGHPMCGVLSGS 362 Query: 364 AKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXX 423 A FTE LTLGYRDAVAV DS +H G+RVVGHEFHRTTV F D Sbjct: 363 ASFTESLTLGYRDAVAVADSPLHNIGDRVVGHEFHRTTVHFVDARQPAWRYSGRGAKMVE 422 Query: 424 XXXVLRGVHAGYLHTHPAAHPQAIARFVASAVPT 457 VL GVHAGYLHTHPAAHP+AIARFVA+A T Sbjct: 423 DGAVLGGVHAGYLHTHPAAHPRAIARFVAAAATT 456 >tr|A4TCF0|A4TCF0_MYCGI Tax_Id=350054 SubName: Full=Hydrogenobyrinic acid a,c-diamide synthase (Glutamine-hydrolysing) / cobyrinate a,c-diamide synthase; EC=6.3.5.-; EC=6.3.5.9;[Mycobacterium gilvum] Length = 454 Score = 629 bits (1623), Expect = e-178 Identities = 326/454 (71%), Positives = 353/454 (77%), Gaps = 5/454 (1%) Query: 4 TTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNL 63 +TPAVVIAAP+SGSGKTTV+TGL+GALR AGH VAPFKVGPDFIDPGYHA+A GRPGRNL Sbjct: 2 STPAVVIAAPSSGSGKTTVATGLMGALRRAGHRVAPFKVGPDFIDPGYHALATGRPGRNL 61 Query: 64 DPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPV 123 DPVLVGE LIGPLY HGS ADIA+VEGVMGLFDGRI D G +GS A VA LLGAPV Sbjct: 62 DPVLVGEPLIGPLYRHGSDDADIAIVEGVMGLFDGRISDGGAGPARGSTAHVAGLLGAPV 121 Query: 124 ILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGA 183 +LVVDARGQS S+AALLHGF TFD V +AGVILNRVGS RH+ VLRQAC+HAGVAVLG+ Sbjct: 122 VLVVDARGQSHSVAALLHGFATFDQTVRLAGVILNRVGSSRHDEVLRQACDHAGVAVLGS 181 Query: 184 IPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWS 243 IPRADEL+VPSRHLGL+TA EHGR A AVAAMTELV RHVDLAAV A A V+ PW+ Sbjct: 182 IPRADELAVPSRHLGLVTAEEHGRHATAAVAAMTELVARHVDLAAVTAVAGGDVADAPWT 241 Query: 244 PCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADAL 303 P + P A TVALA+GKAF+FGYAEH E+L GA V FDPL DPLP AL Sbjct: 242 PAQFAAGPTA-----TVALAAGKAFTFGYAEHREILCAAGADVVTFDPLCDPLPAHTSAL 296 Query: 304 VLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGS 363 VLPGGFPE+F ELSAN+ VR QI LA GAPIHAECAGLTYLVD+LDG PMCGVL GS Sbjct: 297 VLPGGFPEEFVTELSANEPVRSQIRALAAAGAPIHAECAGLTYLVDELDGHPMCGVLAGS 356 Query: 364 AKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXX 423 A FT LTLGYRDAVAV +SS+HA GERV GHEFHRT V F D Sbjct: 357 ASFTPSLTLGYRDAVAVAESSLHAVGERVTGHEFHRTAVQFASDRQAAWQYRGRGGAAVE 416 Query: 424 XXXVLRGVHAGYLHTHPAAHPQAIARFVASAVPT 457 VL GVHAGYLHTH AAHPQAIARFVA+A T Sbjct: 417 DGAVLGGVHAGYLHTHAAAHPQAIARFVAAAATT 450 >tr|A0QIZ3|A0QIZ3_MYCA1 Tax_Id=243243 (cobB)SubName: Full=Cobyrinic Acid a,c-diamide synthase; EC=6.3.1.-;[Mycobacterium avium] Length = 470 Score = 621 bits (1601), Expect = e-176 Identities = 326/455 (71%), Positives = 361/455 (79%), Gaps = 10/455 (2%) Query: 6 PAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDP 65 PAVV+AAPASGSGKTTV+TGLIGALR AG VA FKVGPDFIDPGYH +AAGRPGRNLDP Sbjct: 5 PAVVVAAPASGSGKTTVATGLIGALRRAGRRVAAFKVGPDFIDPGYHGLAAGRPGRNLDP 64 Query: 66 VLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVIL 125 VLVGE+LIGPLYAHG+AGADIAVVEGVMGLFDGRI GS A VA+LLGAPV+L Sbjct: 65 VLVGENLIGPLYAHGAAGADIAVVEGVMGLFDGRIGPSGASPASGSTAHVAALLGAPVVL 124 Query: 126 VVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIP 185 VVDARGQSQSIAALLHGF+TFD+A VAGVILNRVGS RHE VLRQACE AGV VLGAIP Sbjct: 125 VVDARGQSQSIAALLHGFSTFDAATRVAGVILNRVGSARHEQVLRQACEQAGVPVLGAIP 184 Query: 186 RADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPC 245 R+ EL +P+R+LGL+TAVE+GR+AR AV AMT LV RH+DLAAV A A+AR A PW P Sbjct: 185 RSAELELPTRYLGLVTAVEYGRRARLAVEAMTALVARHLDLAAVAAVAAARPVATPWDPA 244 Query: 246 VETSFPVADVAG-----VTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGA 300 V D G TVA+A+GKAFSFGYAEHAELL GA VAEFDPLVD LPDG Sbjct: 245 A----AVGDPGGRGGERATVAVATGKAFSFGYAEHAELLAAAGARVAEFDPLVDALPDGT 300 Query: 301 DALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVL 360 +AL+LPGGFPEQFTAELSAN++VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGVL Sbjct: 301 NALLLPGGFPEQFTAELSANEVVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVL 360 Query: 361 RGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXX 420 G A+FT +LTL YRDAVAVVDS ++AAG+R VGHEFHRTTVTF DD Sbjct: 361 AGQARFTPQLTLAYRDAVAVVDSPLYAAGQRAVGHEFHRTTVTFSDD-YLPAWMYRTQES 419 Query: 421 XXXXXXVLRGVHAGYLHTHPAAHPQAIARFVASAV 455 V GVHA YLHTHPAA P A+ARFV A+ Sbjct: 420 GHRDGAVRAGVHASYLHTHPAAAPAAVARFVGCAL 454 >sp|P63835|COBB_MYCTU Tax_Id=1773 (cobB)RecName: Full=Cobyrinic acid A,C-diamide synthase;[Mycobacterium tuberculosis] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >sp|P63836|COBB_MYCBO Tax_Id=1765 (cobB)RecName: Full=Cobyrinic acid A,C-diamide synthase;[Mycobacterium bovis] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|C6DWZ3|C6DWZ3_MYCTK Tax_Id=478434 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|C1AFW2|C1AFW2_MYCBT Tax_Id=561275 (cobB)SubName: Full=Cobyrinic acid a,c-diamide synthase;[Mycobacterium bovis] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|A5WRA1|A5WRA1_MYCTF Tax_Id=336982 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|A5U6K0|A5U6K0_MYCTA Tax_Id=419947 (cobB)SubName: Full=Cobyrinic acid a,c-diamide synthase;[Mycobacterium tuberculosis] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|A1KMJ1|A1KMJ1_MYCBP Tax_Id=410289 (cobB)SubName: Full=Probable cobyrinic acid A,C-diamide synthase cobB;[Mycobacterium bovis] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|D6G2B3|D6G2B3_MYCTU Tax_Id=478435 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis KZN 605] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|D6FNQ8|D6FNQ8_MYCTU Tax_Id=611304 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis K85] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|D6FK78|D6FK78_MYCTU Tax_Id=611303 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis CPHL_A] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|D6F7X3|D6F7X3_MYCTU Tax_Id=611302 SubName: Full=Cobyrinic acid a,c-diamide synthase;[Mycobacterium tuberculosis T46] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|D5ZK38|D5ZK38_MYCTU Tax_Id=537210 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis T17] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|D5Z731|D5Z731_MYCTU Tax_Id=537209 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis GM 1503] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|D5YIF1|D5YIF1_MYCTU Tax_Id=520140 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis EAS054] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|D5XXI6|D5XXI6_MYCTU Tax_Id=515617 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis T92] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|A4KKB6|A4KKB6_MYCTU Tax_Id=395095 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis str. Haarlem] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|A2VLI1|A2VLI1_MYCTU Tax_Id=348776 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis C] Length = 457 Score = 618 bits (1594), Expect = e-175 Identities = 314/448 (70%), Positives = 358/448 (79%), Gaps = 2/448 (0%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPGRNLDPV Sbjct: 5 AVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPGRNLDPV 64 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 LVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLGAPVILV Sbjct: 65 LVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLGAPVILV 124 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAVLGAIPR Sbjct: 125 VDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAVLGAIPR 184 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCV 246 EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + PW P + Sbjct: 185 TAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHPPWDPVI 244 Query: 247 ETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLP 306 A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G DA+VLP Sbjct: 245 AVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGTDAVVLP 302 Query: 307 GGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKF 366 GGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ GSA+F Sbjct: 303 GGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVVAGSARF 362 Query: 367 TERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXX 426 T+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 363 TQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVDDVRDGA 422 Query: 427 VLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P A+ARFVA A Sbjct: 423 VHSGVHASYLHTHPAATPGAVARFVAHA 450 >tr|Q73VU4|Q73VU4_MYCPA Tax_Id=1770 (cobB)RecName: Full=Cobyrinic acid A,C-diamide synthase;[Mycobacterium paratuberculosis] Length = 470 Score = 617 bits (1590), Expect = e-174 Identities = 325/455 (71%), Positives = 358/455 (78%), Gaps = 10/455 (2%) Query: 6 PAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDP 65 PAVV+AAPASGSGKTTV+TGLIGALR AG VA FKVGPDFIDPGYH + AGRPGRNLDP Sbjct: 5 PAVVVAAPASGSGKTTVATGLIGALRGAGRRVAAFKVGPDFIDPGYHGLTAGRPGRNLDP 64 Query: 66 VLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVIL 125 VLVGE+LIGPLYAHG+AGADIAVVEGVMGLFDGRI GS A VA+LLGAPV+L Sbjct: 65 VLVGENLIGPLYAHGAAGADIAVVEGVMGLFDGRIGPSGASPAAGSTAHVAALLGAPVVL 124 Query: 126 VVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIP 185 VVDARGQSQSIAALLHGF+TFD+A VAGVILNRVGS RHE VLRQA E AGV VLGAIP Sbjct: 125 VVDARGQSQSIAALLHGFSTFDAATRVAGVILNRVGSARHEQVLRQASEQAGVPVLGAIP 184 Query: 186 RADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPC 245 R+ EL +P+R+LGL+TAVE+GR+AR AV AMT LV RHVDLAAV A A+AR PW P Sbjct: 185 RSAELELPTRYLGLVTAVEYGRRARLAVEAMTALVARHVDLAAVAAVAAARPVTTPWDPA 244 Query: 246 VETSFPVADVAG-----VTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGA 300 V D G TVA+A+GKAFSFGYAEHAELL GA VAEFDPLVD LPDG Sbjct: 245 A----AVGDPGGCGGERATVAVATGKAFSFGYAEHAELLAAAGARVAEFDPLVDALPDGT 300 Query: 301 DALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVL 360 DAL+LPGGFPEQFTAELSAN++VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGVL Sbjct: 301 DALLLPGGFPEQFTAELSANEVVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVL 360 Query: 361 RGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXX 420 G A+FT +LTL YRDAVAVVDS ++AAG+R VGHEFHRTTVTF DD Sbjct: 361 AGQARFTPQLTLAYRDAVAVVDSPLYAAGQRAVGHEFHRTTVTFSDD-YPPAWMYRTQES 419 Query: 421 XXXXXXVLRGVHAGYLHTHPAAHPQAIARFVASAV 455 V GVHA YLHTHPAA P A+ARFV A+ Sbjct: 420 GHRDGAVRGGVHASYLHTHPAAAPAAVARFVGCAL 454 >tr|D5PJC9|D5PJC9_9MYCO Tax_Id=525368 (cobB)SubName: Full=Cobyrinic Acid a,c-diamide synthase; EC=6.3.1.-; Flags: Fragment;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 452 Score = 613 bits (1581), Expect = e-173 Identities = 316/453 (69%), Positives = 355/453 (78%), Gaps = 7/453 (1%) Query: 4 TTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNL 63 + PAVV+AAPASGSGKTTV+TGLIGALR AGH VAPFKVGPDFIDPGYH +AAGRPGRNL Sbjct: 3 SVPAVVVAAPASGSGKTTVATGLIGALRRAGHAVAPFKVGPDFIDPGYHGLAAGRPGRNL 62 Query: 64 DPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPV 123 DPVLVGE+L+GPLYAHG+AGADIAV+EGVMGLFDGRI + G +GS A VA LLGAPV Sbjct: 63 DPVLVGEELVGPLYAHGAAGADIAVIEGVMGLFDGRIGSAVAGPAEGSTAHVAGLLGAPV 122 Query: 124 ILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGA 183 ILVVDARGQS SIAALLHGF+TFD+A V GVILNRVGS RHE LRQACE AGVAVLGA Sbjct: 123 ILVVDARGQSHSIAALLHGFSTFDAATRVRGVILNRVGSARHEHALRQACEQAGVAVLGA 182 Query: 184 IPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWS 243 IPR EL +P+R+LGL+TAVE+GR+AR AV AMT+LV HVDL AV A A++R W Sbjct: 183 IPRRAELELPTRYLGLVTAVEYGRRARAAVEAMTDLVAGHVDLPAVAAVAASR-PGPVWD 241 Query: 244 PCVETSFPVADVAG--VTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGAD 301 P V + AG TVA+A+GKAFSF YAEH ELLR GA V EFDPL D LPDG D Sbjct: 242 PAT----AVGETAGGRATVAMAAGKAFSFAYAEHVELLRAAGADVVEFDPLADQLPDGTD 297 Query: 302 ALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLR 361 A++LPGGFPEQFTAELSAND+VR+Q++ELA GAPIHAECAGL YL +LDG PMCGVL Sbjct: 298 AVLLPGGFPEQFTAELSANDIVRRQLNELAAAGAPIHAECAGLIYLATELDGHPMCGVLA 357 Query: 362 GSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXX 421 GSA+FT LTL YRDAVAV DS +++AG+R VGHEFHRT VTF + Sbjct: 358 GSARFTPHLTLAYRDAVAVADSPLYSAGQRAVGHEFHRTAVTFSESYQPAWVYRGNEADP 417 Query: 422 XXXXXVLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPAA P+A+ARFVA A Sbjct: 418 VRDGVVRAGVHASYLHTHPAAAPRAVARFVAHA 450 >tr|D5YVD0|D5YVD0_MYCTU Tax_Id=515616 SubName: Full=Cobyrinic acid a,c-diamide synthase cobB;[Mycobacterium tuberculosis 02_1987] Length = 578 Score = 608 bits (1569), Expect = e-172 Identities = 310/450 (68%), Positives = 354/450 (78%), Gaps = 2/450 (0%) Query: 1 MVGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPG 60 MV AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPG Sbjct: 1 MVMRVSAVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPG 60 Query: 61 RNLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLG 120 RNLDPVLVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLG Sbjct: 61 RNLDPVLVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLG 120 Query: 121 APVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAV 180 APVILVVDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAV Sbjct: 121 APVILVVDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAV 180 Query: 181 LGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQ 240 LGAIPR EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + Sbjct: 181 LGAIPRTAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHP 240 Query: 241 PWSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGA 300 PW P + A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G Sbjct: 241 PWDPVIAVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGT 298 Query: 301 DALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVL 360 DA+VLPGGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMCGV+ Sbjct: 299 DAVVLPGGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCGVV 358 Query: 361 RGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXX 420 GSA+FT+ L LGYRDAVAVVDS++++ GERVVGHEFHRT VTF D Sbjct: 359 AGSARFTQHLKLGYRDAVAVVDSALYSVGERVVGHEFHRTAVTFADSYQPAWVYQGQDVD 418 Query: 421 XXXXXXVLRGVHAGYLHTHPAAHPQAIARF 450 V GVHA YLHTHPAA P+ F Sbjct: 419 DVRDGAVHSGVHASYLHTHPAATPRCGGAF 448 >tr|B2HKR3|B2HKR3_MYCMM Tax_Id=216594 (cobB)SubName: Full=Cobyrinic acid a,C-diamide synthase CobB;[Mycobacterium marinum] Length = 458 Score = 607 bits (1566), Expect = e-172 Identities = 313/453 (69%), Positives = 353/453 (77%), Gaps = 2/453 (0%) Query: 2 VGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGR 61 + + P VVIAAPASGSGKTTV+TGLIGALR AG VAPFKVGPDFIDPGYHA+AAGRPGR Sbjct: 1 MNSIPGVVIAAPASGSGKTTVATGLIGALRQAGRRVAPFKVGPDFIDPGYHALAAGRPGR 60 Query: 62 NLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGA 121 NLDPVLVGE LIGPLYAHG+ GADIAVVEGVMGLFDGRI + G GS+A VA+LLG Sbjct: 61 NLDPVLVGERLIGPLYAHGAQGADIAVVEGVMGLFDGRIEHAVAGPATGSSAHVANLLGT 120 Query: 122 PVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVL 181 PVILVVDARGQS SIAALLHGF+TFDS +AGVILNRVGS RHE VLRQACE AGV V+ Sbjct: 121 PVILVVDARGQSHSIAALLHGFSTFDSKTRIAGVILNRVGSARHEHVLRQACEQAGVPVV 180 Query: 182 GAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQP 241 GAIPR+ EL +P+R+LGL+TAVE+GR+AR AV AMT L+ RHVD+ AV+A A + V P Sbjct: 181 GAIPRSAELELPTRYLGLVTAVEYGRRARLAVEAMTALIARHVDVEAVLAAAGSSVGDAP 240 Query: 242 WSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGAD 301 W P T+ A T+A+A+GKAFSF YAEHAELLR GA V EFDPL +PLP + Sbjct: 241 WDPV--TAIGGAPAGHATIAMAAGKAFSFAYAEHAELLRAAGADVVEFDPLGEPLPADST 298 Query: 302 ALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLR 361 ++LPGGFPEQFTAELSANDLVR+QI +LA GAP+HAECAGL YL +LDG PMC VL Sbjct: 299 GVLLPGGFPEQFTAELSANDLVRRQIKDLAHAGAPLHAECAGLIYLASELDGYPMCDVLA 358 Query: 362 GSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXX 421 GSA+FT LTLGYRDAVAV DS+++AAG RVVGHEFHRTTVTF D Sbjct: 359 GSARFTPHLTLGYRDAVAVADSALYAAGHRVVGHEFHRTTVTFSDRYEPAWVYRGNDAAA 418 Query: 422 XXXXXVLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPA+ P A+ARFVA A Sbjct: 419 VRDGVVHAGVHASYLHTHPASTPDAVARFVAHA 451 >tr|A0PQB5|A0PQB5_MYCUA Tax_Id=362242 (cobB)SubName: Full=Cobyrinic acid a,C-diamide synthase CobB;[Mycobacterium ulcerans] Length = 458 Score = 606 bits (1562), Expect = e-171 Identities = 312/453 (68%), Positives = 352/453 (77%), Gaps = 2/453 (0%) Query: 2 VGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGR 61 + + P VVIAAPASGSGKTTV+TGLIGALR AG VAPFKVGPDFIDPGYHA+AAGRPGR Sbjct: 1 MNSIPGVVIAAPASGSGKTTVATGLIGALRQAGRRVAPFKVGPDFIDPGYHALAAGRPGR 60 Query: 62 NLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGA 121 NLDPVLVGE LIGPLYAHG+ GADIAVVEGVMGLFDGRI + G GS+A VA+LLG Sbjct: 61 NLDPVLVGERLIGPLYAHGAQGADIAVVEGVMGLFDGRIEHAVAGPATGSSAHVANLLGT 120 Query: 122 PVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVL 181 PVILVVDARGQS SIAALLHGF+TFDS +AGVILNRVGS RHE VLRQACE AGV V+ Sbjct: 121 PVILVVDARGQSHSIAALLHGFSTFDSKTRIAGVILNRVGSARHEHVLRQACEQAGVPVV 180 Query: 182 GAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQP 241 GAIPR+ EL +P+R+LGL+TAVE+GR+AR AV AMT L+ RHVD+ AV+A A + V P Sbjct: 181 GAIPRSAELELPTRYLGLVTAVEYGRRARLAVEAMTALIARHVDVEAVLAAAGSSVGDAP 240 Query: 242 WSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGAD 301 W P T+ A T+A+A+GKAFSF YAEHAELLR GA V EFDPL +PLP + Sbjct: 241 WDPV--TAIGGAPAGHATIAMAAGKAFSFAYAEHAELLRAAGADVVEFDPLGEPLPADST 298 Query: 302 ALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLR 361 ++LPGGFPEQFTAELSANDLVR+QI +LA GAP+HAECAGL YL +LDG PMC VL Sbjct: 299 GVLLPGGFPEQFTAELSANDLVRRQIKDLAHAGAPLHAECAGLIYLASELDGYPMCDVLA 358 Query: 362 GSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXX 421 GSA+FT LTLGYRDAVAV DS+++AAG RVVGHEFHRTTVTF D Sbjct: 359 GSARFTPHLTLGYRDAVAVADSALYAAGHRVVGHEFHRTTVTFSDRYEPAWVYRGNDAAA 418 Query: 422 XXXXXVLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVH YLHTHPA+ P A+ARFVA A Sbjct: 419 VRDGVVHAGVHVSYLHTHPASTPDAVARFVAHA 451 >tr|Q0S247|Q0S247_RHOSR Tax_Id=101510 (cobB)SubName: Full=Cobyrinic acid a,c-diamide synthase;[Rhodococcus sp.] Length = 465 Score = 542 bits (1397), Expect = e-152 Identities = 286/453 (63%), Positives = 325/453 (71%), Gaps = 6/453 (1%) Query: 6 PAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDP 65 PAVVIAAPASGSGKTTV+TGL+GALRA+G TVAPFKVGPD+IDPGYH +AAGRPGRNLDP Sbjct: 8 PAVVIAAPASGSGKTTVATGLVGALRASGCTVAPFKVGPDYIDPGYHGLAAGRPGRNLDP 67 Query: 66 VLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTP--QGSAAQVASLLGAPV 123 V+VG IGPLY HGS+G D+AVVEGVMGLFDG+I D + P +GS AQVA+LLGAPV Sbjct: 68 VMVGAQRIGPLYRHGSSGCDLAVVEGVMGLFDGKI-DAASQEPSAEGSTAQVAALLGAPV 126 Query: 124 ILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGA 183 +LVVDARG SQS+AA+LHGF+T+DS V + GVILNRVGSPRHE VLRQACE G+ VLGA Sbjct: 127 VLVVDARGHSQSLAAILHGFSTYDSGVRIGGVILNRVGSPRHEQVLRQACERVGLPVLGA 186 Query: 184 IPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWS 243 +PR EL VPSRHLGLI A EHG A DAV AMT L RH+DL A+ A AS+ V W Sbjct: 187 VPRMAELEVPSRHLGLIPAAEHGADAVDAVDAMTRLAARHLDLPAIRALASSAVDGPVWD 246 Query: 244 PCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADAL 303 P E P+ VA+A G+AF+FGYAEH ELL GA V FDPL D LP G + Sbjct: 247 PAAEAG-PILPGPRPVVAIAGGRAFTFGYAEHRELLGAAGADVITFDPLHDGLPPGTSGV 305 Query: 304 VLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGS 363 VLPGGFPE+ L+ N ++ QI ELA GAPIHAECAGL YL LDG M V+ Sbjct: 306 VLPGGFPEEHAVALAENSVLLTQIRELATAGAPIHAECAGLLYLARSLDGHAMASVVGVD 365 Query: 364 AKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTF--DDDLXXXXXXXXXXXXX 421 A F RLTLGYR+AVAV DS + AAGERVVGHEFHRT++ D Sbjct: 366 ASFGSRLTLGYREAVAVTDSVLFAAGERVVGHEFHRTSLAAAEADGFAPAWGWRPWDGHP 425 Query: 422 XXXXXVLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPA HP+AI RFVA+A Sbjct: 426 AREGFVRGGVHASYLHTHPAGHPEAITRFVAAA 458 >tr|D5Y6T6|D5Y6T6_MYCTU Tax_Id=520141 SubName: Full=Cobyrinic acid a,c-diamide synthase;[Mycobacterium tuberculosis T85] Length = 400 Score = 534 bits (1375), Expect = e-149 Identities = 276/393 (70%), Positives = 319/393 (81%), Gaps = 4/393 (1%) Query: 1 MVGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPG 60 MV AV +AAPASGSGKTT++TGLIGALR AGHTVAPFKVGPDFIDPGYHA+AAGRPG Sbjct: 1 MVMRVSAVAVAAPASGSGKTTIATGLIGALRQAGHTVAPFKVGPDFIDPGYHALAAGRPG 60 Query: 61 RNLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLG 120 RNLDPVLVGE LIGPLYAHG AGADIAV+EGV+GLFDGRI GS A VA+LLG Sbjct: 61 RNLDPVLVGERLIGPLYAHGVAGADIAVIEGVLGLFDGRIGPAGGAPAAGSTAHVAALLG 120 Query: 121 APVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAV 180 APVILVVDARGQS S+AALLHGF+TFD+A +AGVILNRVGS RHE VLRQAC+ AGVAV Sbjct: 121 APVILVVDARGQSHSVAALLHGFSTFDTATRIAGVILNRVGSARHEQVLRQACDQAGVAV 180 Query: 181 LGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQ 240 LGAIPR EL +P+R+LGL+TAVE+GR+AR AV AMT +V RHVDLAAV+ACA ++ + Sbjct: 181 LGAIPRTAELELPTRYLGLVTAVEYGRRARLAVQAMTAVVARHVDLAAVIACAGSQAAHP 240 Query: 241 PWSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGA 300 PW P + A TVA+A+G+AF+FGYAEHAE+LR GA V EFDPL + LP+G Sbjct: 241 PWDPVIAVGNTARQPA--TVAIAAGRAFTFGYAEHAEMLRAAGAEVVEFDPLSETLPEGT 298 Query: 301 DALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVL 360 DA+VLPGGFPEQFTAELSAND VR+QI+ELA GAP+HAECAGL YLV +LDG PMC Sbjct: 299 DAVVLPGGFPEQFTAELSANDTVRRQINELAAAGAPVHAECAGLLYLVSELDGHPMCVCG 358 Query: 361 RGSAKFTERLTLGYRDAVAVVDSSMHAAGERVV 393 R A FT+ L LGYRDA + DS++++ GERV+ Sbjct: 359 RIGA-FTQHLKLGYRDA-SRCDSALYSVGERVL 389 >tr|C1B2Y1|C1B2Y1_RHOOB Tax_Id=632772 (cobB)SubName: Full=Cobyrinic acid a,c-diamide synthase; EC=6.3.5.9;[Rhodococcus opacus] Length = 465 Score = 533 bits (1372), Expect = e-149 Identities = 282/453 (62%), Positives = 322/453 (71%), Gaps = 6/453 (1%) Query: 6 PAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDP 65 PAVVIAAPASGSGKTTV+TGL+GALR +G VAPFKVGPD+IDPGYH +AAGRPGRNLDP Sbjct: 8 PAVVIAAPASGSGKTTVATGLVGALRESGCAVAPFKVGPDYIDPGYHGLAAGRPGRNLDP 67 Query: 66 VLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTP--QGSAAQVASLLGAPV 123 V+VG + I PLY HGS+G+D+AVVEGVMGLFDG+I D + P +GS AQVA+LLGAPV Sbjct: 68 VMVGAERIAPLYRHGSSGSDLAVVEGVMGLFDGKI-DAASHEPSAEGSTAQVAALLGAPV 126 Query: 124 ILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGA 183 +LVVDARG SQS+AA+LHGF+T+DS V + GVILNRVGS RHE VLRQACE G+ VLGA Sbjct: 127 VLVVDARGHSQSLAAVLHGFSTYDSGVRIGGVILNRVGSARHEQVLRQACERVGLPVLGA 186 Query: 184 IPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWS 243 +PR EL VPSRHLGLI A EHG A +AV AMT L RH+DL A+ A A++ V W Sbjct: 187 VPRMAELEVPSRHLGLIPAAEHGADAVNAVDAMTRLAARHLDLPAIRALAASAVDGPVWD 246 Query: 244 PCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADAL 303 P E P TVA+A G+AF+FGYAEH ELL GA V FDPL DPLP G + Sbjct: 247 PAAEVG-PPPPGPRPTVAIAGGRAFTFGYAEHRELLGAAGADVTTFDPLHDPLPPGTSGV 305 Query: 304 VLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGS 363 VLPGGFPE+ L+ N + QI ELA GAPIHAECAGL YL LDG M V+ Sbjct: 306 VLPGGFPEEHAVALAGNAALLAQIRELATAGAPIHAECAGLLYLARSLDGHAMASVVGVD 365 Query: 364 AKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRT--TVTFDDDLXXXXXXXXXXXXX 421 A F RLTLGYR+AVAV DS++ AAGERVVGHEFHRT D Sbjct: 366 AAFGSRLTLGYREAVAVTDSALFAAGERVVGHEFHRTFLAAAEADGFAPAWGWRPWDGAP 425 Query: 422 XXXXXVLRGVHAGYLHTHPAAHPQAIARFVASA 454 V GVHA YLHTHPA HP+AI RFVA+A Sbjct: 426 AREGFVRGGVHASYLHTHPAGHPRAITRFVAAA 458 >tr|D5PMW5|D5PMW5_COREQ Tax_Id=525370 (cobB)SubName: Full=Cobyrinic acid a,c-diamide synthase; EC=6.3.1.-;[Rhodococcus equi ATCC 33707] Length = 460 Score = 526 bits (1354), Expect = e-147 Identities = 281/455 (61%), Positives = 319/455 (70%), Gaps = 6/455 (1%) Query: 4 TTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNL 63 +TPAVVIAAPASGSGKTTV+TGL+GALRAAG VAPFKVGPD+IDPGYHA+AAG PGRNL Sbjct: 6 STPAVVIAAPASGSGKTTVATGLVGALRAAGDRVAPFKVGPDYIDPGYHALAAGLPGRNL 65 Query: 64 DPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTP--QGSAAQVASLLGA 121 D VLVG D IGPL+ HG DIAVVEGVMGLFDG+I D + P +GS AQVA+ LGA Sbjct: 66 DSVLVGADRIGPLFRHGGDDCDIAVVEGVMGLFDGKI-DPSSSAPSAEGSTAQVAAALGA 124 Query: 122 PVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVL 181 PV+LV+DARG SQS+AA+LHGF+T+DSAV + GVILNRVGS RHE VLRQACE G+ VL Sbjct: 125 PVVLVIDARGHSQSLAAVLHGFSTYDSAVRIGGVILNRVGSARHEQVLRQACERVGLPVL 184 Query: 182 GAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQP 241 GA+PR EL VPSRHLGL+ AVEHGR A DAVAAMTEL H+DL A+ A + V Sbjct: 185 GAVPRLAELEVPSRHLGLVPAVEHGRAALDAVAAMTELAAAHLDLDAIRGLAHSSVGDVA 244 Query: 242 WSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGAD 301 W P E PV +ALA G AF+FGYAEH ELL GA V FDPL D LP G Sbjct: 245 WDPAAEIG-PVPSGPRPVIALAGGVAFTFGYAEHRELLDAAGADVVVFDPLHDELPAGTA 303 Query: 302 ALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLR 361 LVLPGGFPE+ LSAN ++ QQ+ +LA GAPIHAECAGL YL LDG M GV+ Sbjct: 304 GLVLPGGFPEEHAVALSANRVLLQQVRQLAADGAPIHAECAGLLYLTRSLDGHAMAGVID 363 Query: 362 GSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVT--FDDDLXXXXXXXXXXX 419 A+F +RLTLGYR+AVAV DS + AG RV GHEFHRT + D Sbjct: 364 VDARFGKRLTLGYREAVAVTDSVLFGAGTRVTGHEFHRTALDAGVADGFGPAWGWRAWDA 423 Query: 420 XXXXXXXVLRGVHAGYLHTHPAAHPQAIARFVASA 454 VHA YLHTHPA +P AI RFV +A Sbjct: 424 GATREGFTAGSVHASYLHTHPAGNPDAIRRFVEAA 458 >tr|Q5YSB1|Q5YSB1_NOCFA Tax_Id=37329 (cobB)SubName: Full=Putative cobyrinic acid a,c-diamide synthase;[Nocardia farcinica] Length = 474 Score = 522 bits (1345), Expect = e-146 Identities = 283/467 (60%), Positives = 318/467 (68%), Gaps = 14/467 (2%) Query: 1 MVGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPG 60 M G PAVV+AAPASGSGKTT++TGLIGALR AGH VAPFKVGPD+IDPGYH +AAGRPG Sbjct: 1 MNGPVPAVVVAAPASGSGKTTLATGLIGALRRAGHRVAPFKVGPDYIDPGYHGLAAGRPG 60 Query: 61 RNLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTP--QGSAAQVASL 118 RNLDPVLVG + I PLY HG+ G D+AVVEGVMGLFDGRI D+ P +GS AQVA L Sbjct: 61 RNLDPVLVGAERIAPLYRHGTVGCDLAVVEGVMGLFDGRI-DEGDPAPVAEGSTAQVAGL 119 Query: 119 LGAPVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGV 178 LGAPV+LVVDARG SQS+AALLHGF TFDS V + GVILNRVGS RHE VLR AC G+ Sbjct: 120 LGAPVVLVVDARGHSQSLAALLHGFATFDSGVRLGGVILNRVGSERHEQVLRAACARVGL 179 Query: 179 AVLGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVS 238 VLGA+PR L VPSRHLGLI AVEHGR A DAVAAMT+LV HVDL AV A A V+ Sbjct: 180 PVLGALPRMGALEVPSRHLGLIPAVEHGRAATDAVAAMTDLVAAHVDLGAVAALARCTVA 239 Query: 239 AQPWSPCVETSFPVADVAGVT-----------VALASGKAFSFGYAEHAELLRGTGATVA 287 W P AD G T +A+A G AF+FGYAEH ELL GA V Sbjct: 240 EPAWDPADVVRTAPADHRGTTDAQPAAADGPVIAMAGGPAFTFGYAEHRELLAAAGARVV 299 Query: 288 EFDPLVDPLPDGADALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYL 347 FDPL D LP GA LVLPGGFPE+ A L+AN + ++ E A G PIHAECAGL YL Sbjct: 300 VFDPLRDELPTGAAGLVLPGGFPEEHAAALAANTPLLTEVRERAAAGLPIHAECAGLLYL 359 Query: 348 VDDLDGAPMCGVLRGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDD 407 LDG + GV+ A+F RLTLGYR+AVA+ DS + AGERV GHEFHRT + Sbjct: 360 TRSLDGHALAGVVDAEAEFGPRLTLGYREAVALADSPLWQAGERVRGHEFHRTRLITAVV 419 Query: 408 LXXXXXXXXXXXXXXXXXXVLRGVHAGYLHTHPAAHPQAIARFVASA 454 + R VHA YLHTHPA +P A RFVA+A Sbjct: 420 DRPAWGWRDPAGATVREGLLTRRVHASYLHTHPAGNPSATVRFVAAA 466 >tr|C0ZY81|C0ZY81_RHOE4 Tax_Id=234621 (cobB)SubName: Full=Cobyrinic acid a,c-diamide synthase; EC=6.3.5.9;[Rhodococcus erythropolis] Length = 458 Score = 521 bits (1343), Expect = e-146 Identities = 278/455 (61%), Positives = 327/455 (71%), Gaps = 7/455 (1%) Query: 4 TTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNL 63 +TPAVVIAAPASGSGKTTV+TGLIGALR +G +VAPFKVGPD+IDPGYH +AAGRPGRNL Sbjct: 5 STPAVVIAAPASGSGKTTVATGLIGALRRSGSSVAPFKVGPDYIDPGYHGLAAGRPGRNL 64 Query: 64 DPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTP--QGSAAQVASLLGA 121 D VLVG D IGPLY HG+AG DIAVVEGVMGLFDG+I D+ P +GS AQVAS+LG+ Sbjct: 65 DTVLVGPDRIGPLYRHGTAGCDIAVVEGVMGLFDGKI-DEANSQPSAEGSTAQVASILGS 123 Query: 122 PVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVL 181 PV+LV+DARG SQS+AA+LHGF T+D+ V + GVILNRVGS RHE VLR AC+ GVAVL Sbjct: 124 PVVLVIDARGHSQSLAAVLHGFATYDAGVRIGGVILNRVGSARHEQVLRHACDKVGVAVL 183 Query: 182 GAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQP 241 G +PR EL VPSRHLGLI A EHG A AV AM++L+ HV+L AV A A++ V A Sbjct: 184 GVVPRLTELEVPSRHLGLIPAAEHGAAAVAAVDAMSDLIASHVELDAVRALAASNVGAAA 243 Query: 242 WSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGAD 301 W P E + VA+A G AF+FGYAEH ELL GA V FDPL D LP G Sbjct: 244 WDPVAEVGAHAE--SRPVVAMAGGPAFTFGYAEHRELLTAAGADVQVFDPLRDELPAGTA 301 Query: 302 ALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLR 361 ALVLPGGFPE+ +L+AN ++ QQ+ +LA GAPIHAECAGL YL LDG M GV+ Sbjct: 302 ALVLPGGFPEEHAVDLAANTVLLQQVRDLADGGAPIHAECAGLLYLARSLDGHSMAGVVG 361 Query: 362 GSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTT-VTFDDDLXXXXXXXXXXXX 420 A F +RLTLGYR+AVA+ DSS+ AG RV GHEFHRT+ V+ D D Sbjct: 362 VDATFGKRLTLGYREAVAISDSSLFEAGFRVTGHEFHRTSLVSADADGCGSAWGWRPWDG 421 Query: 421 XXXXXXVLR-GVHAGYLHTHPAAHPQAIARFVASA 454 +R GVHA YLHTHP P++IA+FV +A Sbjct: 422 GSVREGFVRGGVHASYLHTHPVGQPESIAKFVDAA 456 >tr|B1MDB1|B1MDB1_MYCA9 Tax_Id=561007 SubName: Full=Probable cobyrinic acid A,C-diamide synthase (CobB);[Mycobacterium abscessus] Length = 453 Score = 521 bits (1341), Expect = e-145 Identities = 273/454 (60%), Positives = 326/454 (71%), Gaps = 14/454 (3%) Query: 8 VVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPVL 67 +VIAAPASGSGKTTV+TGL+GALR AGH VAPFKVGPD+IDPGYHA+A GRPGRNLD VL Sbjct: 1 MVIAAPASGSGKTTVATGLMGALRHAGHRVAPFKVGPDYIDPGYHALATGRPGRNLDSVL 60 Query: 68 VGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILVV 127 VG+DLIGPL+ HGS ADIAVVEGVMGLFDGR+ G +GS A++A+LLGAPV+LVV Sbjct: 61 VGDDLIGPLFRHGSRNADIAVVEGVMGLFDGRV-----GDAKGSTAEIAALLGAPVVLVV 115 Query: 128 DARGQSQSIAALLHGFTTF--DSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIP 185 DA+G SQS++ALLHGF ++ + +AGVILNRVGS RH +L A + AG+ V GA+P Sbjct: 116 DAKGYSQSLSALLHGFVAHAAEAGIRIAGVILNRVGSARHRDILTAAADRAGLRVFGALP 175 Query: 186 RADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPC 245 R DELSVPSRHLGL+TAVEHG+ A A++AM +LV HV++ A+ A A + V++ W P Sbjct: 176 RTDELSVPSRHLGLVTAVEHGQAALGAISAMAQLVATHVNVGAIAAAAHSDVTSPIWEPA 235 Query: 246 VETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVL 305 P VALA+G+AF+FGYAEH ELL GA VAEFDP D LP ALV+ Sbjct: 236 EAVGAPTD--REPVVALAAGQAFTFGYAEHRELLAAAGALVAEFDPRSDSLPAETAALVI 293 Query: 306 PGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAK 365 PGGFPEQF +LSAN +RQQ+ E+ PIHAECAGLTYL DLDG PMCGVL A+ Sbjct: 294 PGGFPEQFATDLSANATLRQQVGEMV---GPIHAECAGLTYLCRDLDGVPMCGVLDARAR 350 Query: 366 FTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXX 425 FT+ LTLGYR+AVA+ S + GER+ GHEFHRTTV + +D Sbjct: 351 FTDSLTLGYREAVALTGSVLFEEGERLSGHEFHRTTVDYPEDGAPRAWAWRTADGVRREG 410 Query: 426 XVL--RGVHAGYLHTHPAAHPQAIARFVASAVPT 457 V+ +HA YLHTHPAAHP A ARFVA A T Sbjct: 411 TVVGEGRIHASYLHTHPAAHPSATARFVARAAAT 444 >tr|C3JM31|C3JM31_RHOER Tax_Id=596309 (cobB)SubName: Full=Cobyrinic Acid a,c-diamide synthase; EC=6.3.1.-;[Rhodococcus erythropolis SK121] Length = 450 Score = 517 bits (1331), Expect = e-144 Identities = 275/451 (60%), Positives = 324/451 (71%), Gaps = 7/451 (1%) Query: 8 VVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPVL 67 +VIAAPASGSGKTTV+TGLIGALR +G +VAPFKVGPD+IDPGYH +AAGRPGRNLD VL Sbjct: 1 MVIAAPASGSGKTTVATGLIGALRRSGSSVAPFKVGPDYIDPGYHGLAAGRPGRNLDTVL 60 Query: 68 VGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTP--QGSAAQVASLLGAPVIL 125 VG D IGPLY HG+AG DIAVVEGVMGLFDG+I D+ P +GS AQVAS+LG+PV+L Sbjct: 61 VGPDRIGPLYRHGTAGCDIAVVEGVMGLFDGKI-DEANSQPSAEGSTAQVASILGSPVVL 119 Query: 126 VVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIP 185 V+DARG SQS+AA+LHGF T+D+ V + GVILNRVGS RHE VLR AC+ GVAVLG +P Sbjct: 120 VIDARGHSQSLAAVLHGFATYDAGVRIGGVILNRVGSARHEQVLRHACDKVGVAVLGVVP 179 Query: 186 RADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPC 245 R EL VPSRHLGLI A EHG A AV AM++L+ HVDL AV A A++ +SA W P Sbjct: 180 RLTELEVPSRHLGLIPAAEHGAAAVAAVDAMSDLIASHVDLGAVRALAASNLSAAAWDPV 239 Query: 246 VETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVL 305 E + VA+A G AF+FGYAEH ELL GA V FDPL D LP G ALVL Sbjct: 240 AEVGAHAE--SRPVVAMAGGPAFTFGYAEHRELLTAAGADVQVFDPLRDELPAGTAALVL 297 Query: 306 PGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAK 365 PGGFPE+ +L+AN ++ QQ+ +LA GAPIHAECAGL YL LDG M GV+ A Sbjct: 298 PGGFPEEHAVDLAANTVLLQQVRDLADGGAPIHAECAGLLYLARRLDGHSMAGVVGVDAT 357 Query: 366 FTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTT-VTFDDDLXXXXXXXXXXXXXXXX 424 F +RLTLGYR+AVA+ DSS+ AG RV GHEFHRT+ V+ D D Sbjct: 358 FGKRLTLGYREAVAISDSSLFEAGSRVTGHEFHRTSLVSADADGCGSAWGWRPWDGGSVR 417 Query: 425 XXVLR-GVHAGYLHTHPAAHPQAIARFVASA 454 +R GVHA YLHTHP P++IA+FV +A Sbjct: 418 EGFVRGGVHASYLHTHPVGQPESIAKFVDAA 448 >tr|C6WEP3|C6WEP3_ACTMD Tax_Id=446462 SubName: Full=Cobyrinic acid a,c-diamide synthase;[Actinosynnema mirum] Length = 465 Score = 494 bits (1271), Expect = e-137 Identities = 265/458 (57%), Positives = 312/458 (68%), Gaps = 15/458 (3%) Query: 7 AVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPV 66 A+V+AAPASGSGKTTV+TGL+ ALR AG VAPFKVGPD+IDPGYHA+A GRPGRNLDPV Sbjct: 3 ALVVAAPASGSGKTTVATGLMAALRRAGDAVAPFKVGPDYIDPGYHALATGRPGRNLDPV 62 Query: 67 LVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILV 126 +VGE + L+AHG+ GAD+AVVEGVMGLFDGRI G S A VA LLGAPV+ V Sbjct: 63 MVGEHRVPELFAHGARGADLAVVEGVMGLFDGRIDTDGVG----STAHVAKLLGAPVLFV 118 Query: 127 VDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPR 186 VDARGQS+S+AALLHGF +D V + GV+LN+VGSPRHE VLR AC G+ VLG +PR Sbjct: 119 VDARGQSRSLAALLHGFRGYDPGVRLGGVVLNQVGSPRHEQVLRSACADVGLDVLGVLPR 178 Query: 187 ADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASAR--VSAQPWSP 244 D ++PSRHLGL+TA EHG +A AV A+ + VG HVDLAA+ A A+ V+A+ W P Sbjct: 179 DDRFALPSRHLGLVTAAEHGHEAVAAVEAVADAVGAHVDLAAIRALAATANPVAARAWDP 238 Query: 245 CVE-------TSFPVADVAG-VTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVD-P 295 E +S P V +A+A G AF+FGYAEH ELLR GA V FDPL D Sbjct: 239 DAEIAAVVESSSAPRVPVGSRPVIAVAGGPAFTFGYAEHPELLRAAGADVVVFDPLRDET 298 Query: 296 LPDGADALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAP 355 LP L+LPGGFPEQ AELSAN+ +R I+ LAR GAP+HAEC GL YL LDGAP Sbjct: 299 LPANTSGLLLPGGFPEQHAAELSANEPLRATITALARAGAPVHAECGGLLYLAKSLDGAP 358 Query: 356 MCGVLRGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXX 415 MCGV+ A T RL LGYRDAVA VDS + G RV GHEFHRT ++ Sbjct: 359 MCGVVDSEAAMTPRLVLGYRDAVAPVDSVLLPVGARVTGHEFHRTALSTPHGADPAWRWR 418 Query: 416 XXXXXXXXXXXVLRGVHAGYLHTHPAAHPQAIARFVAS 453 VL VHA YLHTHPA+ P++ RF A+ Sbjct: 419 GHDGRPAAEGFVLGNVHASYLHTHPASIPESAHRFTAA 456 >tr|D5UM40|D5UM40_TSUPA Tax_Id=521096 SubName: Full=Cobyrinic acid a,c-diamide synthase;[Tsukamurella paurometabola DSM 20162] Length = 441 Score = 487 bits (1253), Expect = e-135 Identities = 261/447 (58%), Positives = 300/447 (67%), Gaps = 7/447 (1%) Query: 8 VVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPVL 67 +VIAAP+SGSGKTT++TGL+GAL G TVAPFKVGPD+IDPGYHA+A GR GRNLDPVL Sbjct: 1 MVIAAPSSGSGKTTIATGLMGALARTG-TVAPFKVGPDYIDPGYHALATGRSGRNLDPVL 59 Query: 68 VGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILVV 127 G+ I PLY HG+A AD+AVVEGVMGL+DGRI GS A VA LGAPVILVV Sbjct: 60 CGDHRIAPLYRHGAAEADVAVVEGVMGLYDGRITADGRTQGIGSTADVAESLGAPVILVV 119 Query: 128 DARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPRA 187 D RG SQS+AALL GF T+ + VAGVILNRV SPRHE VLR AC G+ LGA+P A Sbjct: 120 DVRGHSQSLAALLAGFATYRPGIAVAGVILNRVSSPRHERVLRDACAQVGLEALGAVPGA 179 Query: 188 DELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASARVSAQPWSPCVE 247 EL VP+RHLGLI A E G A DAVAAMT+LV RHVD+ + A + W P E Sbjct: 180 AELEVPARHLGLIPAAERGAAAVDAVAAMTDLVARHVDVDRIRDLARPVPAGPAWDPSAE 239 Query: 248 TSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDGADALVLPG 307 VA V G TVALA G AFSFGYAEH +LL GA V FDPL D LP GA A+VLPG Sbjct: 240 ----VARVGGPTVALAGGPAFSFGYAEHEDLLTAAGARVQRFDPLTDELPGGAAAVVLPG 295 Query: 308 GFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGSAKFT 367 GFPE + +L+AN +R+QI L G +HAECAGL YL + LDG PMCGV+ G+A FT Sbjct: 296 GFPEVYAEKLAANTALREQIRRLVADGGLVHAECAGLLYLAESLDGVPMCGVVPGAASFT 355 Query: 368 ERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXXXXXV 427 RL LGYRDAVA+ S+ A GERV GHEFHRT + V Sbjct: 356 PRLRLGYRDAVALTAGSLFAVGERVTGHEFHRTALA--PSGTPAWGWRDGDGAPVTDGHV 413 Query: 428 LRGVHAGYLHTHPAAHPQAIARFVASA 454 GVH+ YLH HPA +P+ R V +A Sbjct: 414 APGVHSSYLHVHPAGYPEVAERLVRAA 440 >tr|A4FM70|A4FM70_SACEN Tax_Id=405948 (cobB)SubName: Full=Cobyrinic acid a,c-diamide synthase; EC=6.3.5.9;[Saccharopolyspora erythraea] Length = 469 Score = 480 bits (1235), Expect = e-133 Identities = 263/453 (58%), Positives = 304/453 (67%), Gaps = 10/453 (2%) Query: 8 VVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDPVL 67 VV+AAP SG GKTTV+TGL+ ALR VAPFKVGPD+IDPGYH VAAGR RNLDPVL Sbjct: 14 VVVAAPGSGHGKTTVATGLLAALRRRSAAVAPFKVGPDYIDPGYHRVAAGRAARNLDPVL 73 Query: 68 VGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQGSAAQVASLLGAPVILVV 127 VGE I PL+ HG+AGA ++VVEGVMGLFDGRI G GS A VA LL APV+LVV Sbjct: 74 VGEQRIVPLFKHGAAGAGLSVVEGVMGLFDGRIGTGGDGPAFGSTAHVAGLLDAPVVLVV 133 Query: 128 DARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGAIPRA 187 DA GQSQS+AALLHGF TF V + GVILNRVGS RHE VLR+A E AG+ V GA+PR Sbjct: 134 DASGQSQSLAALLHGFRTFQPGVRIGGVILNRVGSARHEEVLREAAEVAGLPVFGALPRT 193 Query: 188 DELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASA--RVSAQPWSPC 245 + L VPSRHLGL+TA EHG +A V+AM ++V + VDL +V A A + ++ WSP Sbjct: 194 EGLRVPSRHLGLVTAAEHGGEATRVVSAMADVVEQSVDLDSVAALAESAPALTGDVWSPE 253 Query: 246 VETSFPVADVAG-VTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDP-LPDGADAL 303 E V V G VA+A G AF+FGYAEH ELL GA V DP D LP G L Sbjct: 254 EE----VRRVGGSPVVAVAGGPAFTFGYAEHVELLAAAGAEVVVVDPTRDERLPGGTAGL 309 Query: 304 VLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGVLRGS 363 VLPGGFPEQ AELSAN L+R+ I++ A G P+HAEC GL YLVD+LDG PMCGVLR Sbjct: 310 VLPGGFPEQHVAELSANSLLRKDIADFAASGGPVHAECGGLLYLVDELDGHPMCGVLRAR 369 Query: 364 AKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXXXXXX 423 A + +LTLGYRDAVA DS + A GER+ GHEFHRT + + Sbjct: 370 AAMSPKLTLGYRDAVAATDSVLFAEGERISGHEFHRTVL--EPGAGERPAWRWRAGGVTA 427 Query: 424 XXXVLRGVHAGYLHTHPAAHPQAIARFVASAVP 456 V GVHA YLHTHPA P A+ RF + P Sbjct: 428 EGFVHSGVHASYLHTHPAGGPDAVFRFAEAMRP 460 >tr|D0LBH1|D0LBH1_GORB4 Tax_Id=526226 SubName: Full=Cobyrinic acid a,c-diamide synthase;[Gordonia bronchialis] Length = 476 Score = 477 bits (1227), Expect = e-132 Identities = 268/459 (58%), Positives = 309/459 (67%), Gaps = 8/459 (1%) Query: 6 PAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNLDP 65 PAVVIAAP+SGSGKTTV+TGLIGALRAAGH VAPFKVGPD+IDPGYHAVAAGR GRNLD Sbjct: 5 PAVVIAAPSSGSGKTTVTTGLIGALRAAGHRVAPFKVGPDYIDPGYHAVAAGRVGRNLDS 64 Query: 66 VLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTP--QGSAAQVASLLGAPV 123 LVG + I L+A GSAGADIAVVEGVMGLFDGRI D GS A VA+L+GAPV Sbjct: 65 NLVGAEQIPALFAAGSAGADIAVVEGVMGLFDGRITDDADADSLGTGSTAHVATLIGAPV 124 Query: 124 ILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAVLGA 183 ILVVDA G SQS+AA+LHGF ++ +V +AGV+LNRVGSPRHE VLRQAC GV V G Sbjct: 125 ILVVDAAGHSQSLAAVLHGFLGYEPSVRIAGVVLNRVGSPRHEQVLRQACARVGVPVFGV 184 Query: 184 IPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACASA--RVSAQP 241 + R L+VPSRHLGLI A E +A AV AMT VG +DL A++A AS+ R A Sbjct: 185 LRRDPSLAVPSRHLGLIPAAERTTEAVLAVDAMTAGVGAALDLPAIVAAASSSTRRMAPA 244 Query: 242 WSP--CVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVDPLPDG 299 WS + P + + +A+A+G AF+FGYAEH E+LR GA V EFDPL D LP G Sbjct: 245 WSASDALNAQGPPPENRPL-IAVAAGAAFTFGYAEHTEMLRAAGADVVEFDPLADRLPVG 303 Query: 300 ADALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMCGV 359 +V+ GGFPE+ LSAND +R+ + EL RG P+HAECAGL YL LDG PM GV Sbjct: 304 CAGVVIGGGFPEEHAEALSANDSLRRDLRELTTRGGPVHAECAGLLYLAARLDGHPMSGV 363 Query: 360 LRGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXXXX 419 L F LTLGYRDAVAV DS ++ +G+RV GHEFHR+ VT Sbjct: 364 LDVDGHFGPTLTLGYRDAVAVTDSVLYRSGDRVTGHEFHRSQVTARAASLPPAWGWSGAD 423 Query: 420 XXXXXXXVLRG-VHAGYLHTHPAAHPQAIARFVASAVPT 457 V G VHA YLH HP A P AI RFV A T Sbjct: 424 GRPSVHGVATGSVHASYLHVHPVAVPAAIRRFVHRAAQT 462 >tr|B1W1S3|B1W1S3_STRGG Tax_Id=455632 SubName: Full=Putative cobyrinic acid a,c-diamide synthase;[Streptomyces griseus subsp. griseus] Length = 450 Score = 447 bits (1150), Expect = e-123 Identities = 247/454 (54%), Positives = 302/454 (66%), Gaps = 18/454 (3%) Query: 4 TTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNL 63 +TP +VIAAPASGSGKTTV+TGL+ A A G V+P KVGPD+IDPGYH++A GRPGRNL Sbjct: 3 STPRLVIAAPASGSGKTTVATGLMAAFAARGLAVSPHKVGPDYIDPGYHSLATGRPGRNL 62 Query: 64 DPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQG---SAAQVASLLG 120 D + G +L+ PL+AHGSAG D+AVVEGVMGL+DG + QG S AQVA LL Sbjct: 63 DAYMCGTELVAPLFAHGSAGCDLAVVEGVMGLYDG-------ASGQGDLASTAQVAKLLR 115 Query: 121 APVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAV 180 APV+LVVDA QS+S+AAL+HGF ++D V + GVILN+V S RHEA+LR A + +G+ V Sbjct: 116 APVVLVVDASSQSRSVAALVHGFASWDPEVRIGGVILNKVASDRHEALLRDALDESGLPV 175 Query: 181 LGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACA--SARVS 238 LG I RA +++ PSRHLGL+ E G A DAVAAM E V DL A+MA A + ++ Sbjct: 176 LGVIRRAPQVATPSRHLGLVPVAERGADAVDAVAAMGERVRAGCDLDALMALARTAPALA 235 Query: 239 AQPWSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVD-PLP 297 +PW P P VA+A G AF+F YAEHAELL GA V FDPL D LP Sbjct: 236 DEPWEPAYT---PGPGGEKPVVAVAGGAAFTFAYAEHAELLTAAGADVVVFDPLRDEKLP 292 Query: 298 DGADALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMC 357 G LV+ GGFPE + ELSAN+ +R+ ++ELA GAP+ AECAGL YL +LDG PMC Sbjct: 293 AGTAGLVIGGGFPEMYAPELSANEPLRRAVTELALSGAPVAAECAGLLYLARELDGKPMC 352 Query: 358 GVLRGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXX 417 GVL A+ +ERLTLGYR AVAV DS++ AG R+ GHEFHRT + + Sbjct: 353 GVLDAEARMSERLTLGYRQAVAVSDSALAVAGTRMRGHEFHRTVL--EPGAGTTPAWGMH 410 Query: 418 XXXXXXXXXVLRGVHAGYLHTHPAAHPQAIARFV 451 V RGVHA YLHTH AA P+ RFV Sbjct: 411 QPERRVEGYVQRGVHASYLHTHWAASPEVARRFV 444 >tr|D1WX34|D1WX34_9ACTO Tax_Id=649189 SubName: Full=Cobyrinic acid a,c-diamide synthase;[Streptomyces sp. ACT-1] Length = 450 Score = 447 bits (1150), Expect = e-123 Identities = 247/454 (54%), Positives = 302/454 (66%), Gaps = 18/454 (3%) Query: 4 TTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNL 63 +TP +VIAAPASGSGKTTV+TGL+ A A G V+P KVGPD+IDPGYH++A GRPGRNL Sbjct: 3 STPRLVIAAPASGSGKTTVATGLMAAFAARGLAVSPHKVGPDYIDPGYHSLATGRPGRNL 62 Query: 64 DPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQG---SAAQVASLLG 120 D + G +L+ PL+AHGSAG D+AVVEGVMGL+DG + QG S AQVA LL Sbjct: 63 DAYMCGTELVAPLFAHGSAGCDLAVVEGVMGLYDG-------ASGQGELASTAQVAKLLR 115 Query: 121 APVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAV 180 APV+LVVDA QS+S+AAL+HGF ++D V + GVILN+V S RHEA+LR A + +G+ V Sbjct: 116 APVVLVVDASSQSRSVAALVHGFASWDPEVRIGGVILNKVASDRHEALLRDALDESGLPV 175 Query: 181 LGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACA--SARVS 238 LG I RA +++ PSRHLGL+ E G A DAVAAM E V DL A+MA A + ++ Sbjct: 176 LGVIRRAPQVATPSRHLGLVPVAERGADAVDAVAAMGERVRAGCDLDALMALARTAPALA 235 Query: 239 AQPWSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVD-PLP 297 +PW P P VA+A G AF+F YAEHAELL GA V FDPL D LP Sbjct: 236 DEPWEPAYT---PGPGGEKPVVAVAGGAAFTFAYAEHAELLTAAGADVVVFDPLRDEKLP 292 Query: 298 DGADALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAPMC 357 G LV+ GGFPE + ELSAN+ +R+ ++ELA GAP+ AECAGL YL +LDG PMC Sbjct: 293 AGTAGLVIGGGFPEMYAPELSANEPLRRAVTELALSGAPVAAECAGLLYLARELDGKPMC 352 Query: 358 GVLRGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXXXX 417 GVL A+ +ERLTLGYR AVAV DS++ AG R+ GHEFHRT + + Sbjct: 353 GVLDAEARMSERLTLGYRQAVAVSDSALAVAGTRMRGHEFHRTVL--EPGAGTTPAWGMH 410 Query: 418 XXXXXXXXXVLRGVHAGYLHTHPAAHPQAIARFV 451 V RGVHA YLHTH AA P+ RFV Sbjct: 411 QPERRVEGYVQRGVHASYLHTHWAASPEVARRFV 444 >tr|D6APA3|D6APA3_STRFL Tax_Id=457431 SubName: Full=Cobyrinic acid a,c-diamide synthase;[Streptomyces roseosporus NRRL 15998] Length = 512 Score = 439 bits (1130), Expect = e-121 Identities = 245/456 (53%), Positives = 300/456 (65%), Gaps = 18/456 (3%) Query: 2 VGTTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGR 61 V + P +VIAAPAS SGKTTV+TGL+ A A G V+P KVGPD+IDPGYH++A GRPGR Sbjct: 60 VVSVPRLVIAAPASNSGKTTVATGLMAAFAARGLAVSPHKVGPDYIDPGYHSLATGRPGR 119 Query: 62 NLDPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQG---SAAQVASL 118 NLD + G DL+ PL+AHGSAG D+AVVEGVMGL+DG + QG S AQVA L Sbjct: 120 NLDAYMCGTDLVAPLFAHGSAGCDLAVVEGVMGLYDG-------ASGQGELASTAQVAKL 172 Query: 119 LGAPVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGV 178 L APV+LVVDA QS+S+AAL+HGF ++D V + GVILN+V S RHEA+LR A + +G+ Sbjct: 173 LKAPVVLVVDASSQSRSVAALVHGFASWDPEVRIGGVILNKVASDRHEALLRDALDESGL 232 Query: 179 AVLGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACA--SAR 236 VLG I RA +++ PSRHLGL+ E A DAV AM E V DL A++A A + Sbjct: 233 PVLGVIRRAPQVATPSRHLGLVPVAERQSDAVDAVRAMGERVRAGCDLDALLALARTAPA 292 Query: 237 VSAQPWSPCVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVD-P 295 ++ +PW+P P VA+A G AF+F YAEHAELL GA V FDPL D Sbjct: 293 LADEPWAPAYA---PGPGGEKPVVAVAGGAAFTFAYAEHAELLTAAGAEVVTFDPLRDEK 349 Query: 296 LPDGADALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGAP 355 LP G LV+ GGFPE + ELSAN+ +R+ ++ELA GAP+ AECAGL YL +LDG P Sbjct: 350 LPVGTAGLVIGGGFPEMYAPELSANEPLRRAVTELALSGAPVAAECAGLLYLARELDGKP 409 Query: 356 MCGVLRGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXXX 415 MCGVL A+ +ERLTLGYR AVAV DS + AAG R+ GHEFHRT + + Sbjct: 410 MCGVLDAEARMSERLTLGYRQAVAVSDSPLAAAGTRMRGHEFHRTVL--EPAAGTTPAWG 467 Query: 416 XXXXXXXXXXXVLRGVHAGYLHTHPAAHPQAIARFV 451 V RGVHA YLHTH AA P+ RFV Sbjct: 468 MHQPERRVEGYVQRGVHASYLHTHWAASPEVARRFV 503 >tr|D1XFS3|D1XFS3_9ACTO Tax_Id=647653 SubName: Full=Cobyrinic acid a,c-diamide synthase;[Streptomyces sp. ACTE] Length = 451 Score = 432 bits (1112), Expect = e-119 Identities = 244/457 (53%), Positives = 299/457 (65%), Gaps = 25/457 (5%) Query: 4 TTPAVVIAAPASGSGKTTVSTGLIGALRAAGHTVAPFKVGPDFIDPGYHAVAAGRPGRNL 63 + P +VIAAPAS SGKTTV+TGL+ A G V+P KVGPD+IDPGYHA+A GRPGRNL Sbjct: 3 SVPRLVIAAPASNSGKTTVATGLMAAFAGRGLAVSPHKVGPDYIDPGYHALATGRPGRNL 62 Query: 64 DPVLVGEDLIGPLYAHGSAGADIAVVEGVMGLFDGRICDQMTGTPQG---SAAQVASLLG 120 D + G +L+ PL+ HG+AG D+AVVEGVMGL+DG + QG S AQV+ LL Sbjct: 63 DAYMCGPELVAPLFGHGAAGCDLAVVEGVMGLYDG-------ASGQGELASTAQVSKLLR 115 Query: 121 APVILVVDARGQSQSIAALLHGFTTFDSAVHVAGVILNRVGSPRHEAVLRQACEHAGVAV 180 APV+LVVDA QS+S+AAL+HGF ++D V + GVILN+VGS RHEA+LR+A E G+ V Sbjct: 116 APVVLVVDASSQSRSVAALVHGFASWDPEVRIGGVILNKVGSDRHEALLREALEETGLPV 175 Query: 181 LGAIPRADELSVPSRHLGLITAVEHGRQARDAVAAMTELVGRHVDLAAVMACA--SARVS 238 LGA+ RA +++ PSRHLGL+ E A AVAAM E V DL A++A A + + Sbjct: 176 LGALRRAPQVATPSRHLGLVPVAERQADAVGAVAAMAERVRAGCDLEALLALARTAPALP 235 Query: 239 AQPWSP---CVETSFPVADVAGVTVALASGKAFSFGYAEHAELLRGTGATVAEFDPLVD- 294 W P VE + PV VA+A G AF+F YAEHAELL GA VA FDPL D Sbjct: 236 GAVWEPERQPVEGARPV-------VAVAGGAAFTFAYAEHAELLTAAGAEVAVFDPLRDE 288 Query: 295 PLPDGADALVLPGGFPEQFTAELSANDLVRQQISELARRGAPIHAECAGLTYLVDDLDGA 354 LP G LV+ GGFPE + ELSAN+ +R+ ++ELA GAP+ AECAGL YL +LDG Sbjct: 289 KLPAGTAGLVIGGGFPEVYAPELSANEPLRRAVTELAAAGAPVAAECAGLLYLARELDGR 348 Query: 355 PMCGVLRGSAKFTERLTLGYRDAVAVVDSSMHAAGERVVGHEFHRTTVTFDDDLXXXXXX 414 PMCGVL SA+ +ERLTLGYR AVAV DS + AG R+ GHEFHRT + + Sbjct: 349 PMCGVLDASARMSERLTLGYRSAVAVSDSVLAEAGTRLRGHEFHRTVL--EPGAGAVPAW 406 Query: 415 XXXXXXXXXXXXVLRGVHAGYLHTHPAAHPQAIARFV 451 V RGVHA Y+HTH AA P RFV Sbjct: 407 GLHQPERRVEGFVQRGVHASYVHTHWAASPGVARRFV 443 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.320 0.135 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 3,682,055,641 Number of extensions: 158419022 Number of successful extensions: 491570 Number of sequences better than 10.0: 1461 Number of HSP's gapped: 492440 Number of HSP's successfully gapped: 1515 Length of query: 458 Length of database: 4,236,830,644 Length adjustment: 142 Effective length of query: 316 Effective length of database: 2,460,713,956 Effective search space: 777585610096 Effective search space used: 777585610096 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 82 (36.2 bits)