BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_2780 (353 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|A0QW23|DCUP_MYCS2 Tax_Id=246196 (hemE)RecName: Full=Uroporphy... 655 0.0 sp|A1UF48|DCUP_MYCSK Tax_Id=189918 (hemE)RecName: Full=Uroporphy... 534 e-150 sp|A3PYL0|DCUP_MYCSJ Tax_Id=164757 (hemE)RecName: Full=Uroporphy... 534 e-150 tr|Q1B9W4|Q1B9W4_MYCSS Tax_Id=164756 SubName: Full=Uroporphyrino... 534 e-150 sp|A1T7Z4|DCUP_MYCVP Tax_Id=350058 (hemE)RecName: Full=Uroporphy... 531 e-149 sp|A4TCS1|DCUP_MYCGI Tax_Id=350054 (hemE)RecName: Full=Uroporphy... 525 e-147 sp|A0PT34|DCUP_MYCUA Tax_Id=362242 (hemE)RecName: Full=Uroporphy... 524 e-147 sp|B2HM23|DCUP_MYCMM Tax_Id=216594 (hemE)RecName: Full=Uroporphy... 522 e-146 sp|A0QIL2|DCUP_MYCA1 Tax_Id=243243 (hemE)RecName: Full=Uroporphy... 517 e-145 sp|Q73W61|DCUP_MYCPA Tax_Id=1770 (hemE)RecName: Full=Uroporphyri... 515 e-144 tr|D5PJS5|D5PJS5_9MYCO Tax_Id=525368 (hemE)SubName: Full=Uroporp... 507 e-141 tr|B1MCU3|B1MCU3_MYCA9 Tax_Id=561007 SubName: Full=Probable urop... 494 e-138 sp|P46809|DCUP_MYCLE Tax_Id=1769 (hemE)RecName: Full=Uroporphyri... 494 e-138 sp|B8ZQX2|DCUP_MYCLB Tax_Id=561304 (hemE)RecName: Full=Uroporphy... 494 e-138 sp|O53231|DCUP_MYCTU Tax_Id=1773 (hemE)RecName: Full=Uroporphyri... 492 e-137 sp|A5U630|DCUP_MYCTA Tax_Id=419947 (hemE)RecName: Full=Uroporphy... 492 e-137 sp|C1AFD7|DCUP_MYCBT Tax_Id=561275 (hemE)RecName: Full=Uroporphy... 492 e-137 sp|A1KM16|DCUP_MYCBP Tax_Id=410289 (hemE)RecName: Full=Uroporphy... 492 e-137 tr|C6DLM9|C6DLM9_MYCTK Tax_Id=478434 (hemE)RecName: Full=Uroporp... 492 e-137 tr|A5WQT1|A5WQT1_MYCTF Tax_Id=336982 (hemE)RecName: Full=Uroporp... 492 e-137 tr|D6G3K7|D6G3K7_MYCTU Tax_Id=478435 SubName: Full=Uroporphyrino... 492 e-137 tr|D6FMV5|D6FMV5_MYCTU Tax_Id=611304 SubName: Full=Uroporphyrino... 492 e-137 tr|D6FJQ1|D6FJQ1_MYCTU Tax_Id=611303 SubName: Full=Uroporphyrino... 492 e-137 tr|D6F7E4|D6F7E4_MYCTU Tax_Id=611302 SubName: Full=Uroporphyrino... 492 e-137 tr|D5Z6K6|D5Z6K6_MYCTU Tax_Id=537209 SubName: Full=Uroporphyrino... 492 e-137 tr|D5YV98|D5YV98_MYCTU Tax_Id=515616 SubName: Full=Uroporphyrino... 492 e-137 tr|D5YKQ7|D5YKQ7_MYCTU Tax_Id=520140 SubName: Full=Uroporphyrino... 492 e-137 tr|D5Y7F5|D5Y7F5_MYCTU Tax_Id=520141 SubName: Full=Uroporphyrino... 492 e-137 tr|D5XX06|D5XX06_MYCTU Tax_Id=515617 SubName: Full=Uroporphyrino... 492 e-137 tr|A2VL22|A2VL22_MYCTU Tax_Id=348776 (hemE)RecName: Full=Uroporp... 492 e-137 sp|Q7TY47|DCUP_MYCBO Tax_Id=1765 (hemE)RecName: Full=Uroporphyri... 492 e-137 tr|C3JLI6|C3JLI6_RHOER Tax_Id=596309 (hemE)RecName: Full=Uroporp... 461 e-128 sp|C0ZYX0|DCUP_RHOE4 Tax_Id=234621 (hemE)RecName: Full=Uroporphy... 461 e-128 tr|D5PMC8|D5PMC8_COREQ Tax_Id=525370 (hemE)SubName: Full=Uroporp... 459 e-127 sp|Q5YTA5|DCUP_NOCFA Tax_Id=37329 (hemE)RecName: Full=Uroporphyr... 456 e-126 sp|C1B4A1|DCUP_RHOOB Tax_Id=632772 (hemE)RecName: Full=Uroporphy... 452 e-125 sp|Q0S1F6|DCUP_RHOSR Tax_Id=101510 (hemE)RecName: Full=Uroporphy... 449 e-124 tr|D5UN08|D5UN08_TSUPA Tax_Id=521096 SubName: Full=Uroporphyrino... 420 e-115 tr|D0LCJ0|D0LCJ0_GORB4 Tax_Id=526226 (hemE)RecName: Full=Uroporp... 416 e-114 sp|A4FAS3|DCUP_SACEN Tax_Id=405948 (hemE)RecName: Full=Uroporphy... 413 e-113 tr|C6WBD4|C6WBD4_ACTMD Tax_Id=446462 (hemE)RecName: Full=Uroporp... 407 e-112 tr|D3C6F4|D3C6F4_9ACTO Tax_Id=648999 SubName: Full=Uroporphyrino... 399 e-109 tr|D1SB21|D1SB21_9ACTO Tax_Id=644283 SubName: Full=Uroporphyrino... 398 e-109 tr|C7MYI7|C7MYI7_SACVD Tax_Id=471857 (hemE)RecName: Full=Uroporp... 397 e-109 tr|C4REC8|C4REC8_9ACTO Tax_Id=219305 (hemE)RecName: Full=Uroporp... 388 e-106 >sp|A0QW23|DCUP_MYCS2 Tax_Id=246196 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium smegmatis] Length = 353 Score = 655 bits (1689), Expect = 0.0 Identities = 334/353 (94%), Positives = 334/353 (94%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE Sbjct: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP Sbjct: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA Sbjct: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP Sbjct: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 Query: 241 MTHFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAG 300 MTHFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAG Sbjct: 241 MTHFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAG 300 Query: 301 WPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 WPVVEK HIFNLGHGVLPATDPGIITDAVELVHSL Sbjct: 301 WPVVEKAVRRVVEDGRAAVAAGAAGHIFNLGHGVLPATDPGIITDAVELVHSL 353 >sp|A1UF48|DCUP_MYCSK Tax_Id=189918 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium sp.] Length = 354 Score = 534 bits (1375), Expect = e-150 Identities = 271/354 (76%), Positives = 296/354 (83%), Gaps = 1/354 (0%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 MNTRRELP+SPYLAAA GR P RVPVWFMRQAGRSLPEYR LRA++ M+QACFDA+L+ E Sbjct: 1 MNTRRELPDSPYLAAARGRKPARVPVWFMRQAGRSLPEYRALRARNTMMQACFDADLITE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QPVRRH VDAAILFSDIVVPL+A+GI LDIVPDVGPVID+P+RT DV A+ LE Sbjct: 61 ITLQPVRRHGVDAAILFSDIVVPLRASGIALDIVPDVGPVIDHPVRTAADVAAIRPLERQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 V PV +AVR+LTA LGDVPLIGFAGAPFTLASYLVEGGPS+HHE TKAMMLG TWHA Sbjct: 121 TVEPVEQAVRMLTAALGDVPLIGFAGAPFTLASYLVEGGPSKHHEHTKAMMLGAPDTWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM+ALTD+TIAFLQAQVDAGVDA+QVFDSWAGTLSL DYR YVLPHS+RVF +A AGVP Sbjct: 181 LMSALTDVTIAFLQAQVDAGVDAIQVFDSWAGTLSLADYRAYVLPHSARVFQALAPAGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA-PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLA 299 MTHFGVGTAELLGAMSEA+A GA VVGVDWRTSL DAA RV G+ALQGNLDPVVLLA Sbjct: 241 MTHFGVGTAELLGAMSEAIATSGAPGVVGVDWRTSLTDAAGRVERGSALQGNLDPVVLLA 300 Query: 300 GWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 GWPVVE+ H+FNLGHGVLPATDP I+T VELVHSL Sbjct: 301 GWPVVERAVRAVVEDGRRAVDAGAAGHVFNLGHGVLPATDPEIVTATVELVHSL 354 >sp|A3PYL0|DCUP_MYCSJ Tax_Id=164757 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium sp.] Length = 354 Score = 534 bits (1375), Expect = e-150 Identities = 271/354 (76%), Positives = 296/354 (83%), Gaps = 1/354 (0%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 MNTRRELP+SPYLAAA GR P RVPVWFMRQAGRSLPEYR LRA++ M+QACFDA+L+ E Sbjct: 1 MNTRRELPDSPYLAAARGRKPARVPVWFMRQAGRSLPEYRALRARNTMMQACFDADLITE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QPVRRH VDAAILFSDIVVPL+A+GI LDIVPDVGPVID+P+RT DV A+ LE Sbjct: 61 ITLQPVRRHGVDAAILFSDIVVPLRASGIALDIVPDVGPVIDHPVRTAADVAAIRPLERQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 V PV +AVR+LTA LGDVPLIGFAGAPFTLASYLVEGGPS+HHE TKAMMLG TWHA Sbjct: 121 TVEPVEQAVRMLTAALGDVPLIGFAGAPFTLASYLVEGGPSKHHEHTKAMMLGAPDTWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM+ALTD+TIAFLQAQVDAGVDA+QVFDSWAGTLSL DYR YVLPHS+RVF +A AGVP Sbjct: 181 LMSALTDVTIAFLQAQVDAGVDAIQVFDSWAGTLSLADYRAYVLPHSARVFQALAPAGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA-PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLA 299 MTHFGVGTAELLGAMSEA+A GA VVGVDWRTSL DAA RV G+ALQGNLDPVVLLA Sbjct: 241 MTHFGVGTAELLGAMSEAIATSGAPGVVGVDWRTSLTDAAGRVERGSALQGNLDPVVLLA 300 Query: 300 GWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 GWPVVE+ H+FNLGHGVLPATDP I+T VELVHSL Sbjct: 301 GWPVVERAVRAVVEDGRRAVDAGAAGHVFNLGHGVLPATDPEIVTATVELVHSL 354 >tr|Q1B9W4|Q1B9W4_MYCSS Tax_Id=164756 SubName: Full=Uroporphyrinogen decarboxylase; EC=4.1.1.37;[Mycobacterium sp.] Length = 372 Score = 534 bits (1375), Expect = e-150 Identities = 271/354 (76%), Positives = 296/354 (83%), Gaps = 1/354 (0%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 MNTRRELP+SPYLAAA GR P RVPVWFMRQAGRSLPEYR LRA++ M+QACFDA+L+ E Sbjct: 19 MNTRRELPDSPYLAAARGRKPARVPVWFMRQAGRSLPEYRALRARNTMMQACFDADLITE 78 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QPVRRH VDAAILFSDIVVPL+A+GI LDIVPDVGPVID+P+RT DV A+ LE Sbjct: 79 ITLQPVRRHGVDAAILFSDIVVPLRASGIALDIVPDVGPVIDHPVRTAADVAAIRPLERQ 138 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 V PV +AVR+LTA LGDVPLIGFAGAPFTLASYLVEGGPS+HHE TKAMMLG TWHA Sbjct: 139 TVEPVEQAVRMLTAALGDVPLIGFAGAPFTLASYLVEGGPSKHHEHTKAMMLGAPDTWHA 198 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM+ALTD+TIAFLQAQVDAGVDA+QVFDSWAGTLSL DYR YVLPHS+RVF +A AGVP Sbjct: 199 LMSALTDVTIAFLQAQVDAGVDAIQVFDSWAGTLSLADYRAYVLPHSARVFQALAPAGVP 258 Query: 241 MTHFGVGTAELLGAMSEALA-PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLA 299 MTHFGVGTAELLGAMSEA+A GA VVGVDWRTSL DAA RV G+ALQGNLDPVVLLA Sbjct: 259 MTHFGVGTAELLGAMSEAIATSGAPGVVGVDWRTSLTDAAGRVERGSALQGNLDPVVLLA 318 Query: 300 GWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 GWPVVE+ H+FNLGHGVLPATDP I+T VELVHSL Sbjct: 319 GWPVVERAVRAVVEDGRRAVDAGAAGHVFNLGHGVLPATDPEIVTATVELVHSL 372 >sp|A1T7Z4|DCUP_MYCVP Tax_Id=350058 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium vanbaalenii] Length = 354 Score = 531 bits (1368), Expect = e-149 Identities = 269/354 (75%), Positives = 295/354 (83%), Gaps = 1/354 (0%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 MNTRRELPESPYLAA +GR P RVPVW MRQAGRSLPEYR LRA++ M+QACFDA+L+ E Sbjct: 1 MNTRRELPESPYLAAVAGRKPLRVPVWMMRQAGRSLPEYRALRAKNTMMQACFDADLITE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QPVRRH VDAAILFSDIVVPL+AAGI LDIVPDVGPVI P+RT DV A+ LE Sbjct: 61 ITLQPVRRHGVDAAILFSDIVVPLRAAGIDLDIVPDVGPVIAQPVRTADDVAAIRPLEPS 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 +V PVA A+ L ELGDVPLIGFAGAPFTLASYLVEGGPSR+HERTKAMMLGE++TWHA Sbjct: 121 RVDPVATAIGRLVGELGDVPLIGFAGAPFTLASYLVEGGPSRNHERTKAMMLGETATWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LMTALTD+TIAFL+AQVDAGVDA+QVFDSWAGTLSL DYR YVLPHS+RVFA++A AGVP Sbjct: 181 LMTALTDITIAFLRAQVDAGVDAIQVFDSWAGTLSLADYRTYVLPHSARVFASLAGAGVP 240 Query: 241 MTHFGVGTAELLGAMSEAL-APGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLA 299 MTHFGVGTAELLGAMSEA+ G +VGVDWRTSL DAAARV PG ALQGNLDPVVLLA Sbjct: 241 MTHFGVGTAELLGAMSEAVTGHGVPAMVGVDWRTSLTDAAARVRPGTALQGNLDPVVLLA 300 Query: 300 GWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 GWPVVE+ H+FNLGHGVLPATDP +ITD V LVH L Sbjct: 301 GWPVVERAVRAVVEDGRRAVDAGAVGHVFNLGHGVLPATDPAVITDTVALVHEL 354 >sp|A4TCS1|DCUP_MYCGI Tax_Id=350054 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium gilvum] Length = 354 Score = 525 bits (1353), Expect = e-147 Identities = 267/354 (75%), Positives = 292/354 (82%), Gaps = 1/354 (0%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 MNTRRELPESPYLAAA+GR PHRVPVW MRQAGRSLPEYRELRA++ M+QACFDA+L+ E Sbjct: 1 MNTRRELPESPYLAAAAGRKPHRVPVWMMRQAGRSLPEYRELRAKNTMMQACFDADLITE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QPVRRH VDAAILFSDIVVPL+AAGI LDIVPDVGPVI +PIRT DV + L Sbjct: 61 ITLQPVRRHGVDAAILFSDIVVPLRAAGIDLDIVPDVGPVIAHPIRTAADVATVSPLRRE 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 VAPVA A+ LTA LGDV LIGFAGAPFTLASYL+EGGPSR+HERTKAMMLGE+ TW+A Sbjct: 121 TVAPVATAIGQLTAALGDVALIGFAGAPFTLASYLIEGGPSRNHERTKAMMLGETETWNA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM ALTD+TI FL+ Q+DAGVDA+QVFDSWAGTLSL DYR YVLPHS+RVF +A GVP Sbjct: 181 LMAALTDVTIEFLRVQLDAGVDAIQVFDSWAGTLSLADYRAYVLPHSARVFEALAGYGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA-PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLA 299 MTHFGVGTAELLGAMSEA++ G VVGVDWRTSL DAAARV PG ALQGNLDPVVLLA Sbjct: 241 MTHFGVGTAELLGAMSEAVSGHGVPAVVGVDWRTSLTDAAARVRPGCALQGNLDPVVLLA 300 Query: 300 GWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 GWPVVE+ H+FNLGHGVLPATDP IITDAV LVH L Sbjct: 301 GWPVVERAVRAVVEDGRRAVDAGATGHVFNLGHGVLPATDPAIITDAVALVHQL 354 >sp|A0PT34|DCUP_MYCUA Tax_Id=362242 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium ulcerans] Length = 353 Score = 524 bits (1350), Expect = e-147 Identities = 257/353 (72%), Positives = 289/353 (81%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR QH ML ACF+ E+ CE Sbjct: 1 MSTRRDLPQSPYLAAVAGRKPSRVPVWFMRQAGRSLPEYRALRRQHSMLAACFEPEVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 +TMQP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI P+RT+ DV A+ ++S Sbjct: 61 VTMQPIRRYHVDAAILFSDIVVPLRAAGVDLDIVADVGPVIAAPVRTVADVDAIKPIDSQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 +APV +AV LL AELGD PLIGFAGAPFTLASYLVEGGPSRHH RTKAMML E +TWHA Sbjct: 121 SIAPVLDAVELLVAELGDTPLIGFAGAPFTLASYLVEGGPSRHHARTKAMMLAEPATWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LMT LTDLTI FL Q+ AGVDA+QVFDSWAG LSL DYR+Y LPHS+RVFAT+A GVP Sbjct: 181 LMTKLTDLTIEFLLGQIRAGVDAIQVFDSWAGMLSLADYRQYALPHSARVFATLAEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAG 300 MTHFGVGTAELLGAMSEA+ PG A+VVGVDWRT+LADAAARV PG ALQGNLDPVVLLAG Sbjct: 241 MTHFGVGTAELLGAMSEAVKPGTAKVVGVDWRTALADAAARVQPGTALQGNLDPVVLLAG 300 Query: 301 WPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 WP VE+ ++FNLGHGVLP TDPG++TD V LVHSL Sbjct: 301 WPAVERAARAVVDDGRRAVDAGAAGYVFNLGHGVLPQTDPGVLTDLVSLVHSL 353 >sp|B2HM23|DCUP_MYCMM Tax_Id=216594 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium marinum] Length = 353 Score = 522 bits (1345), Expect = e-146 Identities = 256/353 (72%), Positives = 288/353 (81%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR QH ML ACF+ E+ CE Sbjct: 1 MSTRRDLPQSPYLAAVAGRKPSRVPVWFMRQAGRSLPEYRALRRQHSMLAACFEPEVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 +TMQP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI P+RT+ DV A+ ++ Sbjct: 61 VTMQPIRRYHVDAAILFSDIVVPLRAAGVDLDIVADVGPVIAAPVRTVADVDAIKPIDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 +APV +AV LL AELGD PLIGFAGAPFTLASYLVEGGPSRHH RTKAMML E +TWHA Sbjct: 121 SIAPVLDAVELLVAELGDTPLIGFAGAPFTLASYLVEGGPSRHHARTKAMMLAEPATWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LMT LTDLTI FL Q+ AGVDA+QVFDSWAG LSL DYR+Y LPHS+RVFAT+A GVP Sbjct: 181 LMTKLTDLTIEFLLGQIRAGVDAIQVFDSWAGMLSLADYRQYALPHSARVFATLAEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAG 300 MTHFGVGTAELLGAMSEA+ PG A+VVGVDWRT+LADAAARV PG ALQGNLDPVVLLAG Sbjct: 241 MTHFGVGTAELLGAMSEAVKPGTAKVVGVDWRTALADAAARVQPGTALQGNLDPVVLLAG 300 Query: 301 WPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 WP VE+ ++FNLGHGVLP TDPG++TD V LVHSL Sbjct: 301 WPAVERAARAVVDDGRRAVDAGAAGYVFNLGHGVLPQTDPGVLTDLVSLVHSL 353 >sp|A0QIL2|DCUP_MYCA1 Tax_Id=243243 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium avium] Length = 357 Score = 517 bits (1332), Expect = e-145 Identities = 256/351 (72%), Positives = 283/351 (80%) Query: 3 TRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEIT 62 TRR+LPESPYLAA +GR PHRVPVWFMRQAGRSLPEYR LRAQH ML ACFDAELVCEIT Sbjct: 7 TRRDLPESPYLAAVNGRKPHRVPVWFMRQAGRSLPEYRALRAQHDMLSACFDAELVCEIT 66 Query: 63 MQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQV 122 +QPVRRH VDAAILFSDIVVPL AGI LDIV VGPVI +P+RT DV AM LE +V Sbjct: 67 LQPVRRHDVDAAILFSDIVVPLLGAGIDLDIVAGVGPVIASPVRTAADVAAMKPLERQRV 126 Query: 123 APVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALM 182 P+A+AVRLL + LG+VPLIGFAGAPFTLASYL+EGGPSRHH RTKAMML + +WH LM Sbjct: 127 QPIADAVRLLVSALGEVPLIGFAGAPFTLASYLIEGGPSRHHARTKAMMLADPESWHTLM 186 Query: 183 TALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMT 242 LTD+T+ FL+ Q+DAGVDA+QVFDSWAG LSL +YR YV PHS+RVFA +A GVPMT Sbjct: 187 EKLTDITVGFLRVQLDAGVDAVQVFDSWAGALSLANYRSYVQPHSARVFAALADYGVPMT 246 Query: 243 HFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWP 302 HFGVGTAELLGAMS AL P A VVGVDWRT+LADAA RV+PG ALQGNLDPVVLLAGWP Sbjct: 247 HFGVGTAELLGAMSAALKPAPATVVGVDWRTALADAATRVMPGTALQGNLDPVVLLAGWP 306 Query: 303 VVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 VVE H+FNLGHGVLP TDPG++T+ V LVHSL Sbjct: 307 VVETAARAVVDDGRRAVDAGAAGHVFNLGHGVLPETDPGVLTELVSLVHSL 357 >sp|Q73W61|DCUP_MYCPA Tax_Id=1770 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium paratuberculosis] Length = 357 Score = 515 bits (1327), Expect = e-144 Identities = 256/351 (72%), Positives = 283/351 (80%) Query: 3 TRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEIT 62 TRR+LPESPYLAA +GR PHRVPVWFMRQAGRSLPEYR LRAQH ML ACFDAELVCEIT Sbjct: 7 TRRDLPESPYLAAVNGRKPHRVPVWFMRQAGRSLPEYRALRAQHDMLSACFDAELVCEIT 66 Query: 63 MQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQV 122 +QPVRRH VDAAILFSDIVVPL AGI LDIV VGPVI +P+RT DV AM LE +V Sbjct: 67 LQPVRRHDVDAAILFSDIVVPLLGAGIDLDIVAGVGPVIASPVRTAADVAAMKPLERQRV 126 Query: 123 APVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALM 182 P+A+AVRLL + L +VPLIGFAGAPFTLASYL+EGGPSRHH RTKAMML + +WHALM Sbjct: 127 QPIADAVRLLVSALVEVPLIGFAGAPFTLASYLIEGGPSRHHARTKAMMLADPDSWHALM 186 Query: 183 TALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMT 242 LTD+T+ FL+ Q+DAGVDA+QVFDSWAG LSL +YR YV PHS+RVFA +A GVPMT Sbjct: 187 EKLTDITVGFLRVQLDAGVDAVQVFDSWAGALSLANYRSYVQPHSARVFAALADYGVPMT 246 Query: 243 HFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWP 302 HFGVGTAELLGAMS AL P A VVGVDWRT+LADAA RV+PG ALQGNLDPVVLLAGWP Sbjct: 247 HFGVGTAELLGAMSAALKPAPATVVGVDWRTALADAATRVMPGTALQGNLDPVVLLAGWP 306 Query: 303 VVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 VVE H+FNLGHGVLP TDPG++T+ V LVHSL Sbjct: 307 VVETAARAVVDDGRRAVDAGAAGHVFNLGHGVLPETDPGVLTELVSLVHSL 357 >tr|D5PJS5|D5PJS5_9MYCO Tax_Id=525368 (hemE)SubName: Full=Uroporphyrinogen decarboxylase; EC=4.1.1.37;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 353 Score = 507 bits (1305), Expect = e-141 Identities = 251/353 (71%), Positives = 281/353 (79%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP SPYLAA +GR P R+PVWFMRQAGRSLPEYR LRAQ ML ACFDAELVCE Sbjct: 1 MSTRRDLPASPYLAAVTGRKPARIPVWFMRQAGRSLPEYRALRAQSDMLAACFDAELVCE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QPVRRH VDAAILFSDIVVPL AGI LDIV VGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPVRRHGVDAAILFSDIVVPLLGAGIDLDIVAGVGPVIASPVRTAADVDAMKPLDRQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 ++ PV++AV LL A LG+VPLIGFAGAPFTLASYL+EGGPSRHH RTKAMML + +WHA Sbjct: 121 RIQPVSDAVTLLVAALGEVPLIGFAGAPFTLASYLIEGGPSRHHARTKAMMLADPGSWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTD+T+ FL+AQ++AGVDA+QVFDSWAG LSL DYR YV PHS+RVF +A GVP Sbjct: 181 LMEKLTDITVGFLRAQLEAGVDAIQVFDSWAGALSLADYRAYVQPHSARVFGALAEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAG 300 MTHFGVGTAELLGAMS AL P A VVGVDWRTSLADAA RV PG ALQGNLDPVVL+AG Sbjct: 241 MTHFGVGTAELLGAMSAALQPATATVVGVDWRTSLADAATRVAPGTALQGNLDPVVLMAG 300 Query: 301 WPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 WP VE+ H+FNLGHGVLP T+PG++TD V LVHSL Sbjct: 301 WPAVERAARAVVDDGRRAVDAGAGGHVFNLGHGVLPDTEPGVLTDLVSLVHSL 353 >tr|B1MCU3|B1MCU3_MYCA9 Tax_Id=561007 SubName: Full=Probable uroporphyrinogen decarboxylase (HemE);[Mycobacterium abscessus] Length = 389 Score = 494 bits (1273), Expect = e-138 Identities = 252/351 (71%), Positives = 275/351 (78%), Gaps = 4/351 (1%) Query: 3 TRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEIT 62 TRR+LP SPYL AA+G P PVWFMRQAGRSLPEYR +RA H ML ACF+ ELVCEIT Sbjct: 43 TRRDLPLSPYLVAAAGGVPSHPPVWFMRQAGRSLPEYRAVRADHAMLDACFNPELVCEIT 102 Query: 63 MQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQV 122 +QP+RRH+VDAAILFSDIVVPLKAAGI LDIVPDVGPVI NP+RT DV A+P LE QV Sbjct: 103 LQPIRRHRVDAAILFSDIVVPLKAAGIDLDIVPDVGPVIANPVRTTADVAALPRLEPGQV 162 Query: 123 APVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALM 182 V+ AVRLL ELG PLIGFAGAPFTLASYLVEGGPSRHH+RTKA++LG+ TWHALM Sbjct: 163 EAVSAAVRLLVGELGATPLIGFAGAPFTLASYLVEGGPSRHHQRTKALLLGDPQTWHALM 222 Query: 183 TALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMT 242 TALTD+TIAFL+AQ+DAGVDALQ+FDSWAG LSL DYR VLPHS+R+F A GVPMT Sbjct: 223 TALTDITIAFLRAQLDAGVDALQLFDSWAGALSLADYRAAVLPHSTRIFQEFAGVGVPMT 282 Query: 243 HFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWP 302 HFGVGTAELLGAM EA A VVGVDWRT L AA+RV G ALQGNLDP VLLAGWP Sbjct: 283 HFGVGTAELLGAMGEA----GATVVGVDWRTPLNVAASRVGSGKALQGNLDPAVLLAGWP 338 Query: 303 VVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 VVE HIFNLGHGVLP TDP ++TDA LVHSL Sbjct: 339 VVESEVRRIVAEGRQAVADGAAGHIFNLGHGVLPDTDPAVLTDAAALVHSL 389 >sp|P46809|DCUP_MYCLE Tax_Id=1769 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium leprae] Length = 357 Score = 494 bits (1271), Expect = e-138 Identities = 247/357 (69%), Positives = 282/357 (78%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRREL ESPYLAA SGR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ E+ CE Sbjct: 1 MSTRRELLESPYLAAVSGRKPCRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPEVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL AAGI LDIVPDVGPVI +P+RT D+ AM LE Sbjct: 61 ITLQPLRRYDVDAAILFSDIVVPLCAAGIDLDIVPDVGPVIGDPVRTATDIHAMKPLEPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + P+ +A+ LL A LGDVPLIGFAGAPFTLASYLVEGGPSR+H RTKAMML E ++WH Sbjct: 121 AIQPIFQAISLLVAALGDVPLIGFAGAPFTLASYLVEGGPSRNHPRTKAMMLAEPASWHT 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLT+ FL Q+DAGVDA+QVFDSWAGTLSL+DYR+YVLPHS+R+FAT+A GVP Sbjct: 181 LMDKLTDLTLGFLLGQIDAGVDAIQVFDSWAGTLSLSDYRQYVLPHSARIFATVAEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEAL----APGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTA+LLGAMS A+ PG VVGVDWRTSL DAAARV P ALQGNLDPVV Sbjct: 241 MTHFGVGTADLLGAMSAAVRSGEKPGHQAVVGVDWRTSLTDAAARVEPCTALQGNLDPVV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 LLAGWP VE+ H+FNLGHGVLP TDPG++++ V +HSL Sbjct: 301 LLAGWPAVERVARTVVDDGRRAVVAGAAGHVFNLGHGVLPETDPGVLSELVSFIHSL 357 >sp|B8ZQX2|DCUP_MYCLB Tax_Id=561304 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium leprae] Length = 357 Score = 494 bits (1271), Expect = e-138 Identities = 247/357 (69%), Positives = 282/357 (78%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRREL ESPYLAA SGR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ E+ CE Sbjct: 1 MSTRRELLESPYLAAVSGRKPCRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPEVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL AAGI LDIVPDVGPVI +P+RT D+ AM LE Sbjct: 61 ITLQPLRRYDVDAAILFSDIVVPLCAAGIDLDIVPDVGPVIGDPVRTATDIHAMKPLEPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + P+ +A+ LL A LGDVPLIGFAGAPFTLASYLVEGGPSR+H RTKAMML E ++WH Sbjct: 121 AIQPIFQAISLLVAALGDVPLIGFAGAPFTLASYLVEGGPSRNHPRTKAMMLAEPASWHT 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLT+ FL Q+DAGVDA+QVFDSWAGTLSL+DYR+YVLPHS+R+FAT+A GVP Sbjct: 181 LMDKLTDLTLGFLLGQIDAGVDAIQVFDSWAGTLSLSDYRQYVLPHSARIFATVAEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEAL----APGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTA+LLGAMS A+ PG VVGVDWRTSL DAAARV P ALQGNLDPVV Sbjct: 241 MTHFGVGTADLLGAMSAAVRSGEKPGHQAVVGVDWRTSLTDAAARVEPCTALQGNLDPVV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 LLAGWP VE+ H+FNLGHGVLP TDPG++++ V +HSL Sbjct: 301 LLAGWPAVERVARTVVDDGRRAVVAGAAGHVFNLGHGVLPETDPGVLSELVSFIHSL 357 >sp|O53231|DCUP_MYCTU Tax_Id=1773 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium tuberculosis] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >sp|A5U630|DCUP_MYCTA Tax_Id=419947 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium tuberculosis] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >sp|C1AFD7|DCUP_MYCBT Tax_Id=561275 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium bovis] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >sp|A1KM16|DCUP_MYCBP Tax_Id=410289 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium bovis] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|C6DLM9|C6DLM9_MYCTK Tax_Id=478434 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=UPD; Short=URO-D; EC=4.1.1.37;[Mycobacterium tuberculosis] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|A5WQT1|A5WQT1_MYCTF Tax_Id=336982 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=UPD; Short=URO-D; EC=4.1.1.37;[Mycobacterium tuberculosis] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|D6G3K7|D6G3K7_MYCTU Tax_Id=478435 SubName: Full=Uroporphyrinogen decarboxylase hemE;[Mycobacterium tuberculosis KZN 605] Length = 360 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 4 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 63 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 64 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 123 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 124 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 183 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 184 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 243 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 244 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 303 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 304 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 360 >tr|D6FMV5|D6FMV5_MYCTU Tax_Id=611304 SubName: Full=Uroporphyrinogen decarboxylase hemE;[Mycobacterium tuberculosis K85] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|D6FJQ1|D6FJQ1_MYCTU Tax_Id=611303 SubName: Full=Uroporphyrinogen decarboxylase hemE;[Mycobacterium tuberculosis CPHL_A] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|D6F7E4|D6F7E4_MYCTU Tax_Id=611302 SubName: Full=Uroporphyrinogen decarboxylase;[Mycobacterium tuberculosis T46] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|D5Z6K6|D5Z6K6_MYCTU Tax_Id=537209 SubName: Full=Uroporphyrinogen decarboxylase hemE;[Mycobacterium tuberculosis GM 1503] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|D5YV98|D5YV98_MYCTU Tax_Id=515616 SubName: Full=Uroporphyrinogen decarboxylase hemE;[Mycobacterium tuberculosis 02_1987] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|D5YKQ7|D5YKQ7_MYCTU Tax_Id=520140 SubName: Full=Uroporphyrinogen decarboxylase;[Mycobacterium tuberculosis EAS054] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|D5Y7F5|D5Y7F5_MYCTU Tax_Id=520141 SubName: Full=Uroporphyrinogen decarboxylase;[Mycobacterium tuberculosis T85] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|D5XX06|D5XX06_MYCTU Tax_Id=515617 SubName: Full=Uroporphyrinogen decarboxylase hemE;[Mycobacterium tuberculosis T92] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|A2VL22|A2VL22_MYCTU Tax_Id=348776 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=UPD; Short=URO-D; EC=4.1.1.37;[Mycobacterium tuberculosis C] Length = 357 Score = 492 bits (1267), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >sp|Q7TY47|DCUP_MYCBO Tax_Id=1765 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Mycobacterium bovis] Length = 357 Score = 492 bits (1266), Expect = e-137 Identities = 245/357 (68%), Positives = 277/357 (77%), Gaps = 4/357 (1%) Query: 1 MNTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCE 60 M+TRR+LP+SPYLAA +GR P RVPVWFMRQAGRSLPEYR LR ++ ML ACF+ ++ CE Sbjct: 1 MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACE 60 Query: 61 ITMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESP 120 IT+QP+RR+ VDAAILFSDIVVPL+AAG+ LDIV DVGPVI +P+RT DV AM L+ Sbjct: 61 ITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQ 120 Query: 121 QVAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHA 180 + PV A LL AELGDVPLIGFAGAPFTLASYLVEGGPSRHH KAMML E ++WHA Sbjct: 121 AIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHA 180 Query: 181 LMTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVP 240 LM LTDLTIAFL Q+DAGVDA+QVFDSWAG LS DYR+YVLPHS+RVFA + GVP Sbjct: 181 LMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVP 240 Query: 241 MTHFGVGTAELLGAMSEALA----PGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVV 296 MTHFGVGTAELLGAMSEA+ PG VVGVDWRT L DAAARV+PG ALQGNLDP V Sbjct: 241 MTHFGVGTAELLGAMSEAVTAGERPGRGGVVGVDWRTPLTDAAARVVPGTALQGNLDPAV 300 Query: 297 LLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 +LAGWP VE+ HIFNLGHGVLP +DP ++ D V LVHSL Sbjct: 301 VLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 357 >tr|C3JLI6|C3JLI6_RHOER Tax_Id=596309 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=UPD; Short=URO-D; EC=4.1.1.37;[Rhodococcus erythropolis SK121] Length = 365 Score = 461 bits (1187), Expect = e-128 Identities = 240/352 (68%), Positives = 269/352 (76%), Gaps = 4/352 (1%) Query: 2 NTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEI 61 + RR LP++P LAAA+GR+P R PVWFMRQAGRSLPEYRE+RA ML++CFD LVCEI Sbjct: 18 SARRVLPDAPLLAAATGRTPSRRPVWFMRQAGRSLPEYREIRAGIGMLESCFDPALVCEI 77 Query: 62 TMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQ 121 TMQPVRRH VDAAILFSDIVVPLKAAGI LDIV VGPV+ NPIR++ DV A+P L + Sbjct: 78 TMQPVRRHDVDAAILFSDIVVPLKAAGIDLDIVAGVGPVVANPIRSIADVAALPRLVPEE 137 Query: 122 VAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHAL 181 V +A+AVRLLT ELG PLIGFAGAPFTLASYLVEGGPSR+HE+TKA+M + TWHAL Sbjct: 138 VGAIAQAVRLLTTELGSTPLIGFAGAPFTLASYLVEGGPSRNHEKTKALMHSDPKTWHAL 197 Query: 182 MTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPM 241 + +L D TI FLQAQ+ AGVDA+Q+FDSWAG LSL DYRE+VLPHS RVFA +AAAGVP Sbjct: 198 LGSLADTTICFLQAQLKAGVDAVQLFDSWAGALSLADYREFVLPHSERVFAEVAAAGVPR 257 Query: 242 THFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGW 301 HFGVGT ELLGAM EA A VVGVDWR L AA RV PG ALQGNLDP VL AG Sbjct: 258 IHFGVGTGELLGAMGEA----GADVVGVDWRIPLDVAAGRVGPGKALQGNLDPAVLFAGP 313 Query: 302 PVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 V+++ HIFNLGHGVLP TDP IT AVELVHSL Sbjct: 314 EVIDREVRRIAAEGDRAIEAGAIGHIFNLGHGVLPDTDPTAITAAVELVHSL 365 >sp|C0ZYX0|DCUP_RHOE4 Tax_Id=234621 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Rhodococcus erythropolis] Length = 355 Score = 461 bits (1185), Expect = e-128 Identities = 239/352 (67%), Positives = 268/352 (76%), Gaps = 4/352 (1%) Query: 2 NTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEI 61 + RR LP++P LAAA+GR+P R PVWFMRQAGRSLPEYRE+RA ML++CFD LVCEI Sbjct: 8 SARRVLPDAPLLAAATGRTPSRRPVWFMRQAGRSLPEYREIRAGIGMLESCFDPALVCEI 67 Query: 62 TMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQ 121 TMQPVRRH VDAAILFSDIVVPLKAAGI LDIV VGPV+ NPIR++ DV A+P L + Sbjct: 68 TMQPVRRHDVDAAILFSDIVVPLKAAGIDLDIVAGVGPVVANPIRSIADVAALPRLVPEE 127 Query: 122 VAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHAL 181 V +A+AVRLLT ELG PLIGFAGAPFTLASYLVEGGPSR+HE+TKA+M + TWHAL Sbjct: 128 VGAIAQAVRLLTTELGSTPLIGFAGAPFTLASYLVEGGPSRNHEKTKALMHSDPKTWHAL 187 Query: 182 MTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPM 241 + +L D TI FLQ Q+ AGVDA+Q+FDSWAG LSL DYRE+VLPHS RVFA +AAAGVP Sbjct: 188 LGSLADTTICFLQTQLKAGVDAVQLFDSWAGALSLADYREFVLPHSERVFAEVAAAGVPR 247 Query: 242 THFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGW 301 HFGVGT ELLGAM EA A VVGVDWR L AA RV PG ALQGNLDP VL AG Sbjct: 248 IHFGVGTGELLGAMGEA----GADVVGVDWRIPLDVAAGRVGPGKALQGNLDPAVLFAGP 303 Query: 302 PVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 V+++ HIFNLGHGVLP TDP IT AVELVHSL Sbjct: 304 EVIDREVRRIAAEGDRAIEAGAIGHIFNLGHGVLPDTDPTAITSAVELVHSL 355 >tr|D5PMC8|D5PMC8_COREQ Tax_Id=525370 (hemE)SubName: Full=Uroporphyrinogen decarboxylase; EC=4.1.1.37;[Rhodococcus equi ATCC 33707] Length = 355 Score = 459 bits (1181), Expect = e-127 Identities = 238/350 (68%), Positives = 267/350 (76%), Gaps = 4/350 (1%) Query: 4 RRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITM 63 RR L ++P LAAA+GR PVWFMRQAGRSLPEYRE+RA ML++CFD ELVCEITM Sbjct: 10 RRVLDDAPLLAAATGRPVKHRPVWFMRQAGRSLPEYREIRAGIGMLESCFDPELVCEITM 69 Query: 64 QPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVA 123 QPVRRHKVDAAILFSDIVVPLKAAGI LDIV VGPV+ NP+RT+ DV A+P L +V Sbjct: 70 QPVRRHKVDAAILFSDIVVPLKAAGIDLDIVAGVGPVVANPVRTVADVAALPRLVPDEVG 129 Query: 124 PVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMT 183 VA+AVRLLTAELG+ LIGFAGAPFTLASYLVEGGPSR+HERTKA+M + TWHAL+ Sbjct: 130 AVAQAVRLLTAELGETALIGFAGAPFTLASYLVEGGPSRNHERTKALMHADPKTWHALLG 189 Query: 184 ALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMTH 243 +TD+TIAFLQAQ+ AGVDA+Q+FDSWAG LSL +YRE+VLPHS RVFA + +A VP H Sbjct: 190 RITDVTIAFLQAQLHAGVDAVQLFDSWAGALSLAEYREFVLPHSERVFAEVESAHVPRIH 249 Query: 244 FGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWPV 303 FGVGT ELL AM EA A VVGVDWR L AA RV PG ALQGNLDP VL AGW Sbjct: 250 FGVGTGELLSAMGEA----GADVVGVDWRIPLDVAARRVGPGKALQGNLDPAVLFAGWDA 305 Query: 304 VEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 VE+ HIFNLGHGVLP TDP ++TD VELVHSL Sbjct: 306 VEREVRRICREADAALAAGATGHIFNLGHGVLPDTDPAVLTDVVELVHSL 355 >sp|Q5YTA5|DCUP_NOCFA Tax_Id=37329 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Nocardia farcinica] Length = 354 Score = 456 bits (1174), Expect = e-126 Identities = 235/352 (66%), Positives = 264/352 (75%), Gaps = 4/352 (1%) Query: 2 NTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEI 61 +TRR L ++P+LAAA+G +P R PVWFMRQAGRSLPEYRELRA ML++CFD ELVCEI Sbjct: 7 HTRRRLTDAPFLAAATGATPSRRPVWFMRQAGRSLPEYRELRAGIGMLESCFDPELVCEI 66 Query: 62 TMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQ 121 TMQP+RRH VDAAILFSDIVVPLKAAGI LDIV VGPV+ P+R++ DV+A+P L + Sbjct: 67 TMQPIRRHGVDAAILFSDIVVPLKAAGIDLDIVAGVGPVVAAPVRSVADVRALPRLRPEE 126 Query: 122 VAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHAL 181 V V E VRLL LG PLIGFAGAPFTLASYLVEGGPS+HHERTKAMM + TWH L Sbjct: 127 VGAVVEGVRLLVDALGQTPLIGFAGAPFTLASYLVEGGPSKHHERTKAMMYADPKTWHEL 186 Query: 182 MTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPM 241 + LTD+TIAFL+AQ+DAGVDA+Q+FDSWAG LS DYR +VLPHS RVF +A AGVP Sbjct: 187 LGVLTDITIAFLRAQLDAGVDAVQLFDSWAGALSPADYRAFVLPHSERVFTEIADAGVPR 246 Query: 242 THFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGW 301 HFGVGT ELLGAM EA A VVGVDWR SL +AA RV PG ALQGNLDP VL AG Sbjct: 247 IHFGVGTGELLGAMGEA----GADVVGVDWRVSLTEAARRVGPGKALQGNLDPAVLFAGP 302 Query: 302 PVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 VE HIFNLGHGVLP TDPG++T VELVH L Sbjct: 303 RAVEAHARRIAEEADRALALGAAGHIFNLGHGVLPDTDPGVLTALVELVHEL 354 >sp|C1B4A1|DCUP_RHOOB Tax_Id=632772 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Rhodococcus opacus] Length = 355 Score = 452 bits (1162), Expect = e-125 Identities = 236/350 (67%), Positives = 263/350 (75%), Gaps = 4/350 (1%) Query: 4 RRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITM 63 RR LP++P LAAA GR+P R PVWFMRQAGRSLPEYRE+R+ ML++CFD LVCEITM Sbjct: 10 RRVLPDAPLLAAAEGRAPGRRPVWFMRQAGRSLPEYREIRSGIGMLESCFDPALVCEITM 69 Query: 64 QPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVA 123 QPVRRH VDAAILFSDIVVPLKAAGI LDIV GPV+ NP+R++ DV A+P L +V Sbjct: 70 QPVRRHGVDAAILFSDIVVPLKAAGIDLDIVAGTGPVVANPVRSIADVAALPRLVPEEVG 129 Query: 124 PVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMT 183 VA+AV+LLTAELG PLIGFAGAPFTLASYLVEGGPSR+HERTKA+M + TWHAL+ Sbjct: 130 AVAQAVQLLTAELGSTPLIGFAGAPFTLASYLVEGGPSRNHERTKALMHSDPKTWHALLG 189 Query: 184 ALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMTH 243 L D TI FLQAQ+ AGVDA+Q+FDSWAG LSL +YRE+VLPHS RVFA + +A VP H Sbjct: 190 TLADTTITFLQAQLRAGVDAIQLFDSWAGALSLAEYREFVLPHSERVFAEVESAKVPRIH 249 Query: 244 FGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWPV 303 FGVGT ELLGAM EA A VVGVDWR L AA RV PG ALQGNLDP VL AG Sbjct: 250 FGVGTGELLGAMGEA----GADVVGVDWRIPLDVAARRVGPGKALQGNLDPAVLFAGSAA 305 Query: 304 VEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 VEK HIFNLGHGVLP TDPG +T VELVHSL Sbjct: 306 VEKQVRRITAEADAALAAGATGHIFNLGHGVLPDTDPGALTALVELVHSL 355 >sp|Q0S1F6|DCUP_RHOSR Tax_Id=101510 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Rhodococcus sp.] Length = 355 Score = 449 bits (1156), Expect = e-124 Identities = 235/350 (67%), Positives = 262/350 (74%), Gaps = 4/350 (1%) Query: 4 RRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITM 63 RR LP++P LAAA GR+P R PVWFMRQAGRSLPEYRE+R+ ML++CFD LVCEITM Sbjct: 10 RRVLPDAPLLAAAEGRTPGRRPVWFMRQAGRSLPEYREIRSGIGMLESCFDPALVCEITM 69 Query: 64 QPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVA 123 QPVRRH VDAAILFSDIVVPLKAAGI LDIV GPV+ NP+R++ DV A+P L +V Sbjct: 70 QPVRRHGVDAAILFSDIVVPLKAAGIDLDIVAGTGPVVANPVRSIADVAALPRLVPEEVG 129 Query: 124 PVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMT 183 VA+AV+LLTAELG PLIGFAGAPFTLASYLVEGGPSR+HERTKA+M + TWHAL+ Sbjct: 130 AVAQAVQLLTAELGSTPLIGFAGAPFTLASYLVEGGPSRNHERTKALMHSDPRTWHALLG 189 Query: 184 ALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMTH 243 L D TI FLQ Q+ AGVDA+Q+FDSWAG LSL +YRE+VLPHS RVFA + +A VP H Sbjct: 190 TLADTTITFLQTQLRAGVDAIQLFDSWAGALSLAEYREFVLPHSERVFAEVESAKVPRIH 249 Query: 244 FGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWPV 303 FGVGT ELLGAM EA A VVGVDWR L AA RV PG ALQGNLDP VL AG Sbjct: 250 FGVGTGELLGAMGEA----GADVVGVDWRIPLDVAARRVGPGKALQGNLDPAVLFAGPAA 305 Query: 304 VEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 VEK HIFNLGHGVLP TDPG +T VELVHSL Sbjct: 306 VEKQVRRITAEADAALAAGATGHIFNLGHGVLPDTDPGALTALVELVHSL 355 >tr|D5UN08|D5UN08_TSUPA Tax_Id=521096 SubName: Full=Uroporphyrinogen decarboxylase; EC=4.1.1.37;[Tsukamurella paurometabola DSM 20162] Length = 357 Score = 420 bits (1080), Expect = e-115 Identities = 221/346 (63%), Positives = 253/346 (73%), Gaps = 7/346 (2%) Query: 11 PYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITMQPVRRHK 70 P LAAA+G+ P R PVWFMRQAGRSLPEYR++R MLQ+CF ELV EIT+QPVRRH+ Sbjct: 16 PLLAAAAGQPPARRPVWFMRQAGRSLPEYRKVREGVGMLQSCFMPELVSEITLQPVRRHR 75 Query: 71 VDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVAPVAEAVR 130 DAAILFSDIVVPLKAAGI LDIV +GPVI+ P+R V AMP+L++ QV PVAEAVR Sbjct: 76 TDAAILFSDIVVPLKAAGIDLDIVSGIGPVIEQPVRDAAAVAAMPSLDAEQVEPVAEAVR 135 Query: 131 LLTAELGD-VPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMTALTDLT 189 +L EL D V LIGFAGAPFTLASYLVEGGPSR+HERTKA+M + +TWHAL+ L D+ Sbjct: 136 MLRTELPDGVALIGFAGAPFTLASYLVEGGPSRNHERTKALMYTDPTTWHALLDQLADIA 195 Query: 190 IAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAG--VPMTHFGVG 247 I FL Q +AGV A Q+FDSWAG LSL DYREYVLPHS+RVFA + G +P HFGVG Sbjct: 196 ITFLSVQANAGVQAFQLFDSWAGALSLADYREYVLPHSARVFAALRETGTALPGFHFGVG 255 Query: 248 TAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWPVVEKX 307 T ELLGAM EA A VVGVDWR L +AA RV PG ALQGNLDP L + W +VE Sbjct: 256 TGELLGAMGEA----GADVVGVDWRVPLDEAARRVGPGKALQGNLDPAALASSWEMVEAQ 311 Query: 308 XXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 H+FNLGHGVLP+TDP ++T VELVHSL Sbjct: 312 VRRVCADADAAVAAGATGHVFNLGHGVLPSTDPEVLTRVVELVHSL 357 >tr|D0LCJ0|D0LCJ0_GORB4 Tax_Id=526226 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=UPD; Short=URO-D; EC=4.1.1.37;[Gordonia bronchialis] Length = 354 Score = 416 bits (1069), Expect = e-114 Identities = 217/351 (61%), Positives = 251/351 (71%), Gaps = 5/351 (1%) Query: 4 RRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITM 63 R + P +AAA+G +P R PVWFMRQAGRSLPEYR +RA+H ML++CFDAE+VCEITM Sbjct: 8 RADRSHLPLIAAATGATPSRRPVWFMRQAGRSLPEYRAIRAEHGMLESCFDAEMVCEITM 67 Query: 64 QPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVA 123 QPVRRH VDAAILFSDIVVPLKAAG+ LDIV GPVI PIRT DV +P L V Sbjct: 68 QPVRRHDVDAAILFSDIVVPLKAAGVDLDIVAGTGPVIAEPIRTEADVTRLPRLAPEAVG 127 Query: 124 PVAEAVRLLTAEL-GDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALM 182 VA AV L+ AEL GD LIGFAGAPFTLASYL+EGGPSR++ERTKAMM G W+ LM Sbjct: 128 AVARAVELILAELGGDTALIGFAGAPFTLASYLIEGGPSRNYERTKAMMHGAPVVWNELM 187 Query: 183 TALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMT 242 L D+TIAFL+ Q+DAGVDA+Q+FDSWAG LS DY +V PHSSRV A +A GVP Sbjct: 188 GRLADITIAFLRVQLDAGVDAIQLFDSWAGMLSAADYARFVAPHSSRVLAEVAEYGVPRI 247 Query: 243 HFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWP 302 HFGVGT ELL M+ A A V+GVDWR L +AA RV PG A+QGNLDP +L AG Sbjct: 248 HFGVGTGELLAPMAHA----GADVIGVDWRVPLDEAARRVGPGKAVQGNLDPTMLFAGDD 303 Query: 303 VVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 VV++ HIFNLGHGVLP TDP ++T AV+L+H L Sbjct: 304 VVDREIRRVVDDGDRAIAEGAVGHIFNLGHGVLPGTDPDVLTRAVDLIHRL 354 >sp|A4FAS3|DCUP_SACEN Tax_Id=405948 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=URO-D; Short=UPD; EC=4.1.1.37;[Saccharopolyspora erythraea] Length = 363 Score = 413 bits (1062), Expect = e-113 Identities = 218/359 (60%), Positives = 252/359 (70%), Gaps = 19/359 (5%) Query: 4 RRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITM 63 RR+L ++P LAAA G +P PVWFMRQAGRSLPEYR++R MLQ+C +LVCEIT Sbjct: 10 RRDLADAPLLAAARGETPRHTPVWFMRQAGRSLPEYRKVREGIPMLQSCLTPDLVCEITA 69 Query: 64 QPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVA 123 QPVRRH VDAAILFSDIV+PL AAG+GLDIV GPV+ P+RT DV A+P+L QV+ Sbjct: 70 QPVRRHGVDAAILFSDIVLPLHAAGVGLDIVAGTGPVVAEPVRTAADVAALPSLAPEQVS 129 Query: 124 PVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMT 183 V +AV LL ELG PLIGFAGAPFTLASYLVEGGPSR+HERTKA+M E +TWHAL+ Sbjct: 130 KVGDAVGLLLDELGSTPLIGFAGAPFTLASYLVEGGPSRNHERTKALMHSEPATWHALLE 189 Query: 184 ALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVF----ATMAAAGV 239 L D T+ FL+ Q+ AGVDA+Q+FDSWAG LSL DYRE+VLPHS R+F T AAGV Sbjct: 190 KLADTTLTFLRTQLAAGVDAIQLFDSWAGALSLRDYREFVLPHSRRIFEGVAETPGAAGV 249 Query: 240 PMTHFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGA------ALQGNLD 293 P HFGVGT ELLGAM A A VVGVDWR L AA R+ +QGNLD Sbjct: 250 PKIHFGVGTGELLGAMRSA----GADVVGVDWRVPLDTAAQRLREAGPDQGAPVVQGNLD 305 Query: 294 PVVLLAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHS 352 P VL AGW VE+ HIFNLGHGVLP+TDPG++T VELVH+ Sbjct: 306 PAVLFAGWEAVER-----EVRRILAEGRAAGGHIFNLGHGVLPSTDPGVLTRVVELVHA 359 >tr|C6WBD4|C6WBD4_ACTMD Tax_Id=446462 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=UPD; Short=URO-D; EC=4.1.1.37;[Actinosynnema mirum] Length = 350 Score = 407 bits (1047), Expect = e-112 Identities = 217/352 (61%), Positives = 249/352 (70%), Gaps = 17/352 (4%) Query: 6 ELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITMQP 65 E+ E P L AA G +P R PVWFMRQAGRSLPEYR LRA ML ACFD E+VCEITMQP Sbjct: 7 EMTEPPLLVAARGGTPSRTPVWFMRQAGRSLPEYRALRAGTAMLDACFDPEMVCEITMQP 66 Query: 66 VRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVAPV 125 VRRH VD AILFSDIVVPLKAAG+ LDIV GPV+ +P+RT DV A+P LE+ V PV Sbjct: 67 VRRHDVDGAILFSDIVVPLKAAGVDLDIVAGTGPVVASPVRTRDDVAALPELEAAHVRPV 126 Query: 126 AEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMTAL 185 A+A+ LL ELG+VPLIGFAGAPFTLASYLVEGGPSR+HERTKA+M + WHAL+ + Sbjct: 127 ADAIGLLLKELGNVPLIGFAGAPFTLASYLVEGGPSRNHERTKALMHSDPDLWHALLAKI 186 Query: 186 TDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMTHFG 245 D+T FL+ QV+AGV A+Q+FDSWAG LS DYR +VLPHS+RV ++ GVP HFG Sbjct: 187 ADITAEFLRVQVEAGVKAVQLFDSWAGALSERDYRTFVLPHSTRVLESI--TGVPRIHFG 244 Query: 246 VGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARV------LPGAALQGNLDPVVLLA 299 VGT ELL AM EA A VVGVDWRT L A R+ LP +QGNLDP +L A Sbjct: 245 VGTTELLPAMREA----GADVVGVDWRTPLDVAVRRMVQAAPDLPPPVVQGNLDPALLFA 300 Query: 300 GWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVH 351 G P +E+ HIFNLGHGVLP TDP +IT AVELVH Sbjct: 301 GIPALER-----EVDRIVEEGKVASGHIFNLGHGVLPDTDPDVITKAVELVH 347 >tr|D3C6F4|D3C6F4_9ACTO Tax_Id=648999 SubName: Full=Uroporphyrinogen decarboxylase; EC=4.1.1.37;[Micromonospora sp. L5] Length = 380 Score = 399 bits (1024), Expect = e-109 Identities = 208/345 (60%), Positives = 240/345 (69%), Gaps = 9/345 (2%) Query: 9 ESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITMQPVRR 68 +SP++ A PVWFMRQAGRSLPEYRE+RA ML++C +LV EIT+QPVRR Sbjct: 39 DSPFVRACRREPGPHTPVWFMRQAGRSLPEYREIRANVPMLESCRRPDLVTEITLQPVRR 98 Query: 69 HKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVAPVAEA 128 H VDAAILFSDIVVP+ AAGI LDIVP GPV+ P+RT DV+ + + V+ V EA Sbjct: 99 HGVDAAILFSDIVVPVAAAGIDLDIVPGTGPVVAEPVRTAADVERITPIGRDDVSYVDEA 158 Query: 129 VRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMTALTDL 188 VR L ELGD PLIGFAGAPFTLASYLVEGGPSR H +TKA+M G+ WHAL L ++ Sbjct: 159 VRRLVVELGDTPLIGFAGAPFTLASYLVEGGPSRTHAKTKALMYGDPELWHALCARLAEV 218 Query: 189 TIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMTHFGVGT 248 T+AFLQ Q+DAGV A+Q+FDSWAG LS DYR +VLPHS+ V +A AGVP HFGVGT Sbjct: 219 TLAFLQVQIDAGVSAVQLFDSWAGALSEADYRRFVLPHSTYVLGGLADAGVPRIHFGVGT 278 Query: 249 AELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWPVVEKXX 308 ELLGAM EA A VVGVDWRT L A R+ P A+QGNLDP VLLAGWPVVE Sbjct: 279 GELLGAMGEA----GADVVGVDWRTPLDVATGRIGPDKAVQGNLDPTVLLAGWPVVE--- 331 Query: 309 XXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 H+FNLGHGVLP TDP ++T V LVH L Sbjct: 332 --AEVRRIVEQGRAAPGHVFNLGHGVLPETDPEVLTRVVALVHEL 374 >tr|D1SB21|D1SB21_9ACTO Tax_Id=644283 SubName: Full=Uroporphyrinogen decarboxylase; EC=4.1.1.37;[Micromonospora aurantiaca ATCC 27029] Length = 380 Score = 398 bits (1023), Expect = e-109 Identities = 208/345 (60%), Positives = 240/345 (69%), Gaps = 9/345 (2%) Query: 9 ESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITMQPVRR 68 +SP++ A PVWFMRQAGRSLPEYRE+RA ML++C +LV EIT+QPVRR Sbjct: 39 DSPFVRACRREPGPHTPVWFMRQAGRSLPEYREIRANVPMLESCRRPDLVTEITLQPVRR 98 Query: 69 HKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVAPVAEA 128 H VDAAILFSDIVVP+ AAGI LDIVP GPV+ P+RT DV+ + + V+ V EA Sbjct: 99 HGVDAAILFSDIVVPVAAAGIDLDIVPGTGPVVAEPVRTAADVERITPIGRDDVSFVDEA 158 Query: 129 VRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMTALTDL 188 VR L ELGD PLIGFAGAPFTLASYLVEGGPSR H +TKA+M G+ WHAL L ++ Sbjct: 159 VRRLVVELGDTPLIGFAGAPFTLASYLVEGGPSRTHAKTKALMYGDPELWHALCARLAEV 218 Query: 189 TIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMTHFGVGT 248 T+AFLQ Q+DAGV A+Q+FDSWAG LS DYR +VLPHS+ V +A AGVP HFGVGT Sbjct: 219 TLAFLQVQIDAGVSAVQLFDSWAGALSEADYRRFVLPHSTYVLGGLADAGVPRIHFGVGT 278 Query: 249 AELLGAMSEALAPGAARVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWPVVEKXX 308 ELLGAM EA A VVGVDWRT L A R+ P A+QGNLDP VLLAGWPVVE Sbjct: 279 GELLGAMGEA----GADVVGVDWRTPLDVATGRIGPDKAVQGNLDPTVLLAGWPVVE--- 331 Query: 309 XXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 H+FNLGHGVLP TDP ++T V LVH L Sbjct: 332 --TEVRRIVEQGRAAPGHVFNLGHGVLPETDPEVLTRVVALVHEL 374 >tr|C7MYI7|C7MYI7_SACVD Tax_Id=471857 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=UPD; Short=URO-D; EC=4.1.1.37;[Saccharomonospora viridis] Length = 353 Score = 397 bits (1021), Expect = e-109 Identities = 208/356 (58%), Positives = 246/356 (69%), Gaps = 13/356 (3%) Query: 2 NTRRELPESPYLAAASGRSPHRVPVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEI 61 + RR+L ++P L AA G +P VPVWFMRQAGRSLPEYR++R ML ACFD EL+ EI Sbjct: 7 SARRDLSDAPLLVAARGGTPAHVPVWFMRQAGRSLPEYRKVREGVPMLTACFDPELLAEI 66 Query: 62 TMQPVRRHKVDAAILFSDIVVPLKAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQ 121 T+QPVRRH VDAAILFSDIVVPL AAG +DIV GPV+ +P+R+ DV A+P LE Q Sbjct: 67 TLQPVRRHGVDAAILFSDIVVPLYAAGTDIDIVAGTGPVVAHPVRSRADVAALPRLEPEQ 126 Query: 122 VAPVAEAVRLLTAELGDVPLIGFAGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHAL 181 + PVA+ VRLL +LG PLIGFAGAPFTLASYL+EGGPS+ H RTKA+M GE WH L Sbjct: 127 LKPVADGVRLLVEQLGRTPLIGFAGAPFTLASYLIEGGPSKDHARTKALMHGEPELWHEL 186 Query: 182 MTALTDLTIAFLQAQVDAGVDALQVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPM 241 AL + FL+ Q+DAGVDA+Q+FDSWAG LS DYRE+VLPHS+ V +A+ GVP Sbjct: 187 AGALAQTALTFLRVQLDAGVDAVQLFDSWAGALSAKDYREFVLPHSTTVLEGIASYGVPR 246 Query: 242 THFGVGTAELLGAMSEALAPGAARVVGVDWRTSLADAAARVL----PGAALQGNLDPVVL 297 HFGVGT ELL M +A A VVGVDWR L +A R+ P +QGNLDP +L Sbjct: 247 IHFGVGTGELLADMRDA----GADVVGVDWRVPLDEAVRRLTTSDRPAPVVQGNLDPALL 302 Query: 298 LAGWPVVEKXXXXXXXXXXXXXXXXXXXHIFNLGHGVLPATDPGIITDAVELVHSL 353 A WPV+E HIFNLGHGVLP TDP ++T VELVHSL Sbjct: 303 TAPWPVIE-----AEVRRIVSEGRAAGGHIFNLGHGVLPETDPEVLTRIVELVHSL 353 >tr|C4REC8|C4REC8_9ACTO Tax_Id=219305 (hemE)RecName: Full=Uroporphyrinogen decarboxylase; Short=UPD; Short=URO-D; EC=4.1.1.37;[Micromonospora sp. ATCC 39149] Length = 363 Score = 388 bits (996), Expect = e-106 Identities = 204/329 (62%), Positives = 234/329 (71%), Gaps = 9/329 (2%) Query: 25 PVWFMRQAGRSLPEYRELRAQHRMLQACFDAELVCEITMQPVRRHKVDAAILFSDIVVPL 84 PVWFMRQAGRSLPEYRE+R ML++C ELV EIT+QPVRRH VDAAILFSDIVVP+ Sbjct: 38 PVWFMRQAGRSLPEYREIRKNVGMLESCRRPELVAEITLQPVRRHGVDAAILFSDIVVPV 97 Query: 85 KAAGIGLDIVPDVGPVIDNPIRTLGDVQAMPALESPQVAPVAEAVRLLTAELGDVPLIGF 144 AAG+ LDIV GPV+ P+RT DV+ + + V+ V EAVRLL AELGD PLIGF Sbjct: 98 AAAGVELDIVAGTGPVVAEPVRTAADVERIRPITRDDVSCVDEAVRLLVAELGDTPLIGF 157 Query: 145 AGAPFTLASYLVEGGPSRHHERTKAMMLGESSTWHALMTALTDLTIAFLQAQVDAGVDAL 204 AGAPFTLASYLVEGGPSR H +TKA+M G+ WHAL L ++T+AFL+ QVDAGV A+ Sbjct: 158 AGAPFTLASYLVEGGPSRTHAKTKALMYGDPELWHALCARLAEVTLAFLRVQVDAGVSAV 217 Query: 205 QVFDSWAGTLSLTDYREYVLPHSSRVFATMAAAGVPMTHFGVGTAELLGAMSEALAPGAA 264 Q+FDSWAG LS DYR YVLPHS+RV A +A AGVP HFGVGTAELL AM EA A Sbjct: 218 QLFDSWAGALSEADYRRYVLPHSARVLAGLADAGVPRIHFGVGTAELLPAMGEA----GA 273 Query: 265 RVVGVDWRTSLADAAARVLPGAALQGNLDPVVLLAGWPVVEKXXXXXXXXXXXXXXXXXX 324 VVGVDWRT L A+ R+ A+QGNLDP VL A WPVVE Sbjct: 274 DVVGVDWRTPLDVASRRIGADKAVQGNLDPCVLFAPWPVVE-----AEVRRILAEGRATP 328 Query: 325 XHIFNLGHGVLPATDPGIITDAVELVHSL 353 H+FNLGHGVLP TDP ++T V LVH + Sbjct: 329 GHVFNLGHGVLPETDPDVLTRVVALVHEV 357 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.321 0.135 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 2,687,508,148 Number of extensions: 103676155 Number of successful extensions: 288149 Number of sequences better than 10.0: 1815 Number of HSP's gapped: 283717 Number of HSP's successfully gapped: 1828 Length of query: 353 Length of database: 4,236,830,644 Length adjustment: 139 Effective length of query: 214 Effective length of database: 2,498,237,548 Effective search space: 534622835272 Effective search space used: 534622835272 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 81 (35.8 bits)