BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_3194 (353 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|A0QX70|BIOB_MYCS2 Tax_Id=246196 (bioB)RecName: Full=Biotin sy... 684 0.0 sp|Q1B7F4|BIOB_MYCSS Tax_Id=164756 (bioB)RecName: Full=Biotin sy... 608 e-172 sp|A1UHL9|BIOB_MYCSK Tax_Id=189918 (bioB)RecName: Full=Biotin sy... 608 e-172 sp|A3Q142|BIOB_MYCSJ Tax_Id=164757 (bioB)RecName: Full=Biotin sy... 608 e-172 sp|A1T8V0|BIOB_MYCVP Tax_Id=350058 (bioB)RecName: Full=Biotin sy... 606 e-171 sp|A4T9L9|BIOB_MYCGI Tax_Id=350054 (bioB)RecName: Full=Biotin sy... 595 e-168 sp|B1MBZ3|BIOB_MYCA9 Tax_Id=561007 (bioB)RecName: Full=Biotin sy... 588 e-166 sp|Q5YYR3|BIOB_NOCFA Tax_Id=37329 (bioB)RecName: Full=Biotin syn... 579 e-163 sp|Q740Q9|BIOB_MYCPA Tax_Id=1770 (bioB)RecName: Full=Biotin synt... 578 e-163 sp|A0QHJ1|BIOB_MYCA1 Tax_Id=243243 (bioB)RecName: Full=Biotin sy... 577 e-163 tr|D5UNP6|D5UNP6_TSUPA Tax_Id=521096 SubName: Full=Biotin syntha... 576 e-162 tr|D5P2S4|D5P2S4_9MYCO Tax_Id=525368 (bioB)SubName: Full=Biotin ... 575 e-162 sp|B2HQ93|BIOB_MYCMM Tax_Id=216594 (bioB)RecName: Full=Biotin sy... 573 e-162 sp|A0PP05|BIOB_MYCUA Tax_Id=362242 (bioB)RecName: Full=Biotin sy... 572 e-161 sp|Q0SHW6|BIOB_RHOSR Tax_Id=101510 (bioB)RecName: Full=Biotin sy... 572 e-161 tr|C1AU09|C1AU09_RHOOB Tax_Id=632772 (bioB)SubName: Full=Biotin ... 570 e-161 tr|C1A0R1|C1A0R1_RHOE4 Tax_Id=234621 (bioB)SubName: Full=Biotin ... 570 e-160 tr|C3JIY2|C3JIY2_RHOER Tax_Id=596309 (bioB)SubName: Full=Biotin ... 570 e-160 sp|P0A506|BIOB_MYCTU Tax_Id=1773 (bioB)RecName: Full=Biotin synt... 569 e-160 sp|A5WMR0|BIOB_MYCTF Tax_Id=336982 (bioB)RecName: Full=Biotin sy... 569 e-160 sp|A5U2U5|BIOB_MYCTA Tax_Id=419947 (bioB)RecName: Full=Biotin sy... 569 e-160 sp|A1KJ05|BIOB_MYCBP Tax_Id=410289 (bioB)RecName: Full=Biotin sy... 569 e-160 sp|P0A507|BIOB_MYCBO Tax_Id=1765 (bioB)RecName: Full=Biotin synt... 569 e-160 tr|D0LA15|D0LA15_GORB4 Tax_Id=526226 SubName: Full=Biotin syntha... 569 e-160 tr|C6DSL9|C6DSL9_MYCTK Tax_Id=478434 SubName: Full=Biotin synthe... 569 e-160 tr|C1ANL1|C1ANL1_MYCBT Tax_Id=561275 (bioB)SubName: Full=Biotin ... 569 e-160 tr|D6G8R2|D6G8R2_MYCTU Tax_Id=478435 SubName: Full=Biotin synthe... 569 e-160 tr|D6FTB1|D6FTB1_MYCTU Tax_Id=611304 SubName: Full=Biotin synthe... 569 e-160 tr|D6FH98|D6FH98_MYCTU Tax_Id=611303 SubName: Full=Biotin synthe... 569 e-160 tr|D6F8V1|D6F8V1_MYCTU Tax_Id=611302 SubName: Full=Biotin syntha... 569 e-160 tr|D5ZG31|D5ZG31_MYCTU Tax_Id=537210 SubName: Full=Biotin synthe... 569 e-160 tr|D5Z468|D5Z468_MYCTU Tax_Id=537209 SubName: Full=Biotin synthe... 569 e-160 tr|D5YF96|D5YF96_MYCTU Tax_Id=520140 SubName: Full=Biotin synthe... 569 e-160 tr|D5Y3N3|D5Y3N3_MYCTU Tax_Id=520141 SubName: Full=Biotin synthe... 569 e-160 tr|D5XWW4|D5XWW4_MYCTU Tax_Id=515617 SubName: Full=Biotin synthe... 569 e-160 tr|A4KHB4|A4KHB4_MYCTU Tax_Id=395095 SubName: Full=Biotin synthe... 569 e-160 tr|A2VI81|A2VI81_MYCTU Tax_Id=348776 SubName: Full=Biotin synthe... 569 e-160 tr|D5YTF8|D5YTF8_MYCTU Tax_Id=515616 SubName: Full=Biotin synthe... 566 e-159 tr|D5PNW2|D5PNW2_COREQ Tax_Id=525370 (bioB)SubName: Full=Biotin ... 566 e-159 sp|P46715|BIOB_MYCLE Tax_Id=1769 (bioB)RecName: Full=Biotin synt... 553 e-155 sp|B8ZR86|BIOB_MYCLB Tax_Id=561304 (bioB)RecName: Full=Biotin sy... 553 e-155 tr|C4REH6|C4REH6_9ACTO Tax_Id=219305 SubName: Full=Biotin syntha... 523 e-146 sp|A4X585|BIOB_SALTO Tax_Id=369723 (bioB)RecName: Full=Biotin sy... 521 e-146 sp|A8LUR1|BIOB_SALAI Tax_Id=391037 (bioB)RecName: Full=Biotin sy... 520 e-146 tr|D1S9H1|D1S9H1_9ACTO Tax_Id=644283 SubName: Full=Biotin syntha... 518 e-145 >sp|A0QX70|BIOB_MYCS2 Tax_Id=246196 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium smegmatis] Length = 353 Score = 684 bits (1766), Expect = 0.0 Identities = 344/353 (97%), Positives = 344/353 (97%) Query: 1 MFEVFRDLFNPQEDGVTQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDL 60 MFEVFRDLFNPQEDGVTQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDL Sbjct: 1 MFEVFRDLFNPQEDGVTQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDL 60 Query: 61 LSLAHEVRMRWCGPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAA 120 LSLAHEVRMRWCGPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAA Sbjct: 61 LSLAHEVRMRWCGPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAA 120 Query: 121 KQTAKTGATEFCIVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLAD 180 KQTAKTGATEFCIVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLAD Sbjct: 121 KQTAKTGATEFCIVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLAD 180 Query: 181 MGVHRYNHNLETARSFFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAE 240 MGVHRYNHNLETARSFFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAE Sbjct: 181 MGVHRYNHNLETARSFFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAE 240 Query: 241 FAANLAELNPHEVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGRE 300 FAANLAELNPHEVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGRE Sbjct: 241 FAANLAELNPHEVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGRE 300 Query: 301 ITLGDLGAKKGILGGINAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 ITLGDLGAKKGILGGINAVIVGNYLTTLGRPAEA MPIKALNATL Sbjct: 301 ITLGDLGAKKGILGGINAVIVGNYLTTLGRPAEADLQLLDDLQMPIKALNATL 353 >sp|Q1B7F4|BIOB_MYCSS Tax_Id=164756 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium sp.] Length = 331 Score = 608 bits (1568), Expect = e-172 Identities = 304/330 (92%), Positives = 315/330 (95%) Query: 24 TDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIIS 83 +D+L VAREQVLERGVGL+Q QTLQVLQLPD+RLDDLL+LAHEVRM WCGPDVEVEGIIS Sbjct: 2 SDILAVAREQVLERGVGLNQDQTLQVLQLPDDRLDDLLALAHEVRMAWCGPDVEVEGIIS 61 Query: 84 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 143 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER Sbjct: 62 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121 Query: 144 LLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTT 203 LLAQVAAGIEAIRNEVDIQIACSLGMLT EQV+RL++MGVHRYNHNLETARSFF NVVTT Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTAEQVERLSEMGVHRYNHNLETARSFFTNVVTT 181 Query: 204 HTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPG 263 HTWEERWDTL MVREAGMEVCCGGILGMGETLEQRAEFAANLAEL+PHEVPLNFLNPRPG Sbjct: 182 HTWEERWDTLRMVREAGMEVCCGGILGMGETLEQRAEFAANLAELDPHEVPLNFLNPRPG 241 Query: 264 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 323 TPFGDLEVLPA+EALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN Sbjct: 242 TPFGDLEVLPAAEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 301 Query: 324 YLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 YLTTLGRPAEA MPIKALNA+L Sbjct: 302 YLTTLGRPAEADLELLDDLQMPIKALNASL 331 >sp|A1UHL9|BIOB_MYCSK Tax_Id=189918 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium sp.] Length = 331 Score = 608 bits (1568), Expect = e-172 Identities = 304/330 (92%), Positives = 315/330 (95%) Query: 24 TDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIIS 83 +D+L VAREQVLERGVGL+Q QTLQVLQLPD+RLDDLL+LAHEVRM WCGPDVEVEGIIS Sbjct: 2 SDILAVAREQVLERGVGLNQDQTLQVLQLPDDRLDDLLALAHEVRMAWCGPDVEVEGIIS 61 Query: 84 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 143 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER Sbjct: 62 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121 Query: 144 LLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTT 203 LLAQVAAGIEAIRNEVDIQIACSLGMLT EQV+RL++MGVHRYNHNLETARSFF NVVTT Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTAEQVERLSEMGVHRYNHNLETARSFFTNVVTT 181 Query: 204 HTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPG 263 HTWEERWDTL MVREAGMEVCCGGILGMGETLEQRAEFAANLAEL+PHEVPLNFLNPRPG Sbjct: 182 HTWEERWDTLRMVREAGMEVCCGGILGMGETLEQRAEFAANLAELDPHEVPLNFLNPRPG 241 Query: 264 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 323 TPFGDLEVLPA+EALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN Sbjct: 242 TPFGDLEVLPAAEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 301 Query: 324 YLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 YLTTLGRPAEA MPIKALNA+L Sbjct: 302 YLTTLGRPAEADLELLDDLQMPIKALNASL 331 >sp|A3Q142|BIOB_MYCSJ Tax_Id=164757 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium sp.] Length = 331 Score = 608 bits (1568), Expect = e-172 Identities = 304/330 (92%), Positives = 315/330 (95%) Query: 24 TDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIIS 83 +D+L VAREQVLERGVGL+Q QTLQVLQLPD+RLDDLL+LAHEVRM WCGPDVEVEGIIS Sbjct: 2 SDILAVAREQVLERGVGLNQDQTLQVLQLPDDRLDDLLALAHEVRMAWCGPDVEVEGIIS 61 Query: 84 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 143 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER Sbjct: 62 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121 Query: 144 LLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTT 203 LLAQVAAGIEAIRNEVDIQIACSLGMLT EQV+RL++MGVHRYNHNLETARSFF NVVTT Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTAEQVERLSEMGVHRYNHNLETARSFFTNVVTT 181 Query: 204 HTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPG 263 HTWEERWDTL MVREAGMEVCCGGILGMGETLEQRAEFAANLAEL+PHEVPLNFLNPRPG Sbjct: 182 HTWEERWDTLRMVREAGMEVCCGGILGMGETLEQRAEFAANLAELDPHEVPLNFLNPRPG 241 Query: 264 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 323 TPFGDLEVLPA+EALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN Sbjct: 242 TPFGDLEVLPAAEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 301 Query: 324 YLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 YLTTLGRPAEA MPIKALNA+L Sbjct: 302 YLTTLGRPAEADLELLDDLQMPIKALNASL 331 >sp|A1T8V0|BIOB_MYCVP Tax_Id=350058 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium vanbaalenii] Length = 331 Score = 606 bits (1562), Expect = e-171 Identities = 302/330 (91%), Positives = 314/330 (95%) Query: 24 TDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIIS 83 TD+L VAREQVL RG GLDQ QTLQVLQLPD+RLDDLL+LAHEVRM WCGPDVEVEGIIS Sbjct: 2 TDILAVAREQVLVRGEGLDQDQTLQVLQLPDDRLDDLLALAHEVRMAWCGPDVEVEGIIS 61 Query: 84 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 143 LKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAKTGATEFCIVAAVRGPDER Sbjct: 62 LKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121 Query: 144 LLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTT 203 LLAQVAAGIEAIRNEVDIQIACSLGMLT++QV+RL++MGVHRYNHNLETARSFF NVVTT Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTQDQVERLSEMGVHRYNHNLETARSFFTNVVTT 181 Query: 204 HTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPG 263 H+WEERWDTL MVREAGMEVCCGGILGMGETLEQRAEFAANLAEL+PHEVPLNFLNPRPG Sbjct: 182 HSWEERWDTLQMVREAGMEVCCGGILGMGETLEQRAEFAANLAELDPHEVPLNFLNPRPG 241 Query: 264 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 323 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIVGN Sbjct: 242 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKQGILGGINAVIVGN 301 Query: 324 YLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 YLTTLGRPAEA MPIKALNATL Sbjct: 302 YLTTLGRPAEADLQLLDDLQMPIKALNATL 331 >sp|A4T9L9|BIOB_MYCGI Tax_Id=350054 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium gilvum] Length = 331 Score = 595 bits (1533), Expect = e-168 Identities = 298/330 (90%), Positives = 313/330 (94%) Query: 24 TDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIIS 83 +D+L VAREQVLERGVGLDQ QTLQVLQLPD+RLD+LL+LAHEVRM CGPDVEVEGIIS Sbjct: 2 SDILAVAREQVLERGVGLDQDQTLQVLQLPDDRLDELLALAHEVRMAHCGPDVEVEGIIS 61 Query: 84 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 143 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER Sbjct: 62 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 121 Query: 144 LLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTT 203 LLAQVAAGIEAIRNEVDIQIACSLGMLT++QV+RL+ MGVHRYNHNLETARSFF NVVTT Sbjct: 122 LLAQVAAGIEAIRNEVDIQIACSLGMLTQDQVERLSAMGVHRYNHNLETARSFFTNVVTT 181 Query: 204 HTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPG 263 H+WEERW+TL MVREAGMEVCCGGILGMGE+L QRAEFAANLAEL+PHEVPLNFLNPRPG Sbjct: 182 HSWEERWETLQMVREAGMEVCCGGILGMGESLGQRAEFAANLAELDPHEVPLNFLNPRPG 241 Query: 264 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 323 TPFGDLEVLPA+EALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIVGN Sbjct: 242 TPFGDLEVLPATEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKQGILGGINAVIVGN 301 Query: 324 YLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 YLTTLGRPAEA MPIKALNATL Sbjct: 302 YLTTLGRPAEADLQLLDDLQMPIKALNATL 331 >sp|B1MBZ3|BIOB_MYCA9 Tax_Id=561007 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium abscessus] Length = 342 Score = 588 bits (1516), Expect = e-166 Identities = 293/334 (87%), Positives = 311/334 (93%) Query: 20 AINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVE 79 A DVL VAREQVLE+GVGL Q Q L+VLQLPD+RL++LL+LAHEVRMRWCGP+VEVE Sbjct: 9 AATDADVLAVAREQVLEQGVGLTQEQVLRVLQLPDDRLEELLALAHEVRMRWCGPEVEVE 68 Query: 80 GIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRG 139 GIISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRG Sbjct: 69 GIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRG 128 Query: 140 PDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPN 199 PDERLLAQVAAGIEAIRNEVDIQIACSLGMLT+EQV RL+ MGVHRYNHNLETA+S FPN Sbjct: 129 PDERLLAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDRLSAMGVHRYNHNLETAKSHFPN 188 Query: 200 VVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLN 259 VVTTH+WEERWDTL MVREAGMEVCCGGILGMGETLEQRAEFAANLAEL P EVPLNFLN Sbjct: 189 VVTTHSWEERWDTLKMVREAGMEVCCGGILGMGETLEQRAEFAANLAELEPDEVPLNFLN 248 Query: 260 PRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAV 319 PRPGTPFGDLEVLPAS+AL+AVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAV Sbjct: 249 PRPGTPFGDLEVLPASDALRAVAAFRLALPRTMLRFAGGREITLGDLGAKQGILGGINAV 308 Query: 320 IVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 IVGNYLTTLGRPAEA MPIKALN++L Sbjct: 309 IVGNYLTTLGRPAEADLELLDDLQMPIKALNSSL 342 >sp|Q5YYR3|BIOB_NOCFA Tax_Id=37329 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Nocardia farcinica] Length = 337 Score = 579 bits (1493), Expect = e-163 Identities = 288/338 (85%), Positives = 310/338 (91%), Gaps = 1/338 (0%) Query: 16 VTQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPD 75 +TQA + TD+L++AREQVLERG GL Q QTL VL+L D+RL++LL LAHEVRM+WCGP+ Sbjct: 1 MTQAPVQ-TDILEIAREQVLERGEGLTQDQTLAVLRLGDDRLEELLGLAHEVRMKWCGPE 59 Query: 76 VEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVA 135 VEVEGIISLKTGGCPEDCHFCSQSGLF SPVR+AWLD+PSLVEAAKQTAKTGATEFCIVA Sbjct: 60 VEVEGIISLKTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKTGATEFCIVA 119 Query: 136 AVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARS 195 AVRGPD RL+AQVAAG+EAIRNEVDIQ+ACSLGMLT+EQV +LA MGVHRYNHNLETA+S Sbjct: 120 AVRGPDARLMAQVAAGVEAIRNEVDIQVACSLGMLTQEQVDQLAAMGVHRYNHNLETAKS 179 Query: 196 FFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPL 255 FPNVVTTHTWEERWDTL MVREAGMEVCCGGILGMGETLEQRAEFAA LAEL P EVPL Sbjct: 180 HFPNVVTTHTWEERWDTLRMVREAGMEVCCGGILGMGETLEQRAEFAAQLAELEPDEVPL 239 Query: 256 NFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGG 315 NFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRT+LRFAGGREITLGDLGAK+GILGG Sbjct: 240 NFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTILRFAGGREITLGDLGAKQGILGG 299 Query: 316 INAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 INAVIVGNYLTTLGRPAE+ MPIKALN TL Sbjct: 300 INAVIVGNYLTTLGRPAESDLDLLGELKMPIKALNETL 337 >sp|Q740Q9|BIOB_MYCPA Tax_Id=1770 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium paratuberculosis] Length = 344 Score = 578 bits (1489), Expect = e-163 Identities = 287/335 (85%), Positives = 308/335 (91%) Query: 19 AAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEV 78 A I D+L VAR QVLE G GL + Q LQVL+LPD+RLDDLL+LAHEVRMRWCGP+VEV Sbjct: 10 AEIGNEDILAVARRQVLEGGQGLSRDQVLQVLRLPDDRLDDLLALAHEVRMRWCGPEVEV 69 Query: 79 EGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVR 138 EGIISLKTGGCPEDCHFCSQSGLFASPVRSA LD+PSLVEAAKQTAK+GATEFCIVAAVR Sbjct: 70 EGIISLKTGGCPEDCHFCSQSGLFASPVRSARLDIPSLVEAAKQTAKSGATEFCIVAAVR 129 Query: 139 GPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFP 198 GPDERLLAQVAAGIEA+RNEV+I IACSLGMLT EQV++LA+MGVHRYNHNLETARSFFP Sbjct: 130 GPDERLLAQVAAGIEAVRNEVEINIACSLGMLTAEQVEQLAEMGVHRYNHNLETARSFFP 189 Query: 199 NVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFL 258 NVVTTHTWEERWDTL+MVR+AGMEVCCGGILGMGETLEQRAEFAA LAEL P EVPLNFL Sbjct: 190 NVVTTHTWEERWDTLSMVRDAGMEVCCGGILGMGETLEQRAEFAAELAELGPDEVPLNFL 249 Query: 259 NPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINA 318 NPRPGTPFGDLEV+PA+EALK+VAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINA Sbjct: 250 NPRPGTPFGDLEVMPATEALKSVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINA 309 Query: 319 VIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 VIVGNYLTTLGRPAE+ MP+K LNA+L Sbjct: 310 VIVGNYLTTLGRPAESDLELLDDLQMPLKGLNASL 344 >sp|A0QHJ1|BIOB_MYCA1 Tax_Id=243243 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium avium] Length = 345 Score = 577 bits (1488), Expect = e-163 Identities = 287/332 (86%), Positives = 307/332 (92%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N D+L VAR QVLE G GL + Q LQVL+LPD+RLDDLL+LAHEVRMRWCGP+VEVEGI Sbjct: 14 NDEDILAVARRQVLEGGQGLSRDQVLQVLRLPDDRLDDLLALAHEVRMRWCGPEVEVEGI 73 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSA LD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 74 ISLKTGGCPEDCHFCSQSGLFASPVRSARLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 133 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERLLAQVAAGIEAIRNEV+I IACSLGMLT EQV++LA+MGVHRYNHNLETARSFFPNVV Sbjct: 134 ERLLAQVAAGIEAIRNEVEINIACSLGMLTAEQVEQLAEMGVHRYNHNLETARSFFPNVV 193 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERWDTL+MVR+AGMEVCCGGILGMGETLEQRAEFAA LAEL P EVPLNFLNPR Sbjct: 194 TTHTWEERWDTLSMVRDAGMEVCCGGILGMGETLEQRAEFAAELAELGPDEVPLNFLNPR 253 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPFGDLEV+PA+EALK+VAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV Sbjct: 254 PGTPFGDLEVMPATEALKSVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 313 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAE+ MP+K LNA+L Sbjct: 314 GNYLTTLGRPAESDLELLDDLQMPLKGLNASL 345 >tr|D5UNP6|D5UNP6_TSUPA Tax_Id=521096 SubName: Full=Biotin synthase; EC=2.8.1.6;[Tsukamurella paurometabola DSM 20162] Length = 335 Score = 576 bits (1484), Expect = e-162 Identities = 283/329 (86%), Positives = 305/329 (92%) Query: 25 DVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIISL 84 D++DVAREQVLERG GL+Q Q L VLQL D+RLD++L LAHEVRM+WCGP+VEVEGIISL Sbjct: 7 DIIDVAREQVLERGEGLNQEQVLAVLQLSDDRLDEVLQLAHEVRMKWCGPEVEVEGIISL 66 Query: 85 KTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDERL 144 KTGGCPEDCHFCSQSGLF SPVRSAW+D+PSLVEAAKQTAKTGATEFCIVAAVRGPD+RL Sbjct: 67 KTGGCPEDCHFCSQSGLFESPVRSAWIDIPSLVEAAKQTAKTGATEFCIVAAVRGPDKRL 126 Query: 145 LAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTTH 204 L+QVAAGIEAIRNEVDIQIACSLGMLT+EQV +L DMGVHRYNHNLET+RS FPNVVTTH Sbjct: 127 LSQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLKDMGVHRYNHNLETSRSHFPNVVTTH 186 Query: 205 TWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPGT 264 TWEERWDTL MVREAGMEVCCGGILGMGE+LEQRAEFAANLAEL P EVPLNFLNPRPGT Sbjct: 187 TWEERWDTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPGT 246 Query: 265 PFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGNY 324 PFGDL+VLPA+EALK+VAAFRLALPRT+LRFAGGREITLGDLGA+KGILGGINAVIVGNY Sbjct: 247 PFGDLDVLPAAEALKSVAAFRLALPRTILRFAGGREITLGDLGAEKGILGGINAVIVGNY 306 Query: 325 LTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LTTLGRPAE MPIKALN +L Sbjct: 307 LTTLGRPAETDLDLLNELKMPIKALNDSL 335 >tr|D5P2S4|D5P2S4_9MYCO Tax_Id=525368 (bioB)SubName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 344 Score = 575 bits (1482), Expect = e-162 Identities = 293/344 (85%), Positives = 309/344 (89%), Gaps = 6/344 (1%) Query: 16 VTQAAI------NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRM 69 +TQAA + D+L VAREQVLERG GL + Q L+VLQLPD+RLDDLL+LAHEVRM Sbjct: 1 MTQAATRPATGAHDADILAVAREQVLERGEGLSRDQVLRVLQLPDDRLDDLLALAHEVRM 60 Query: 70 RWCGPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGAT 129 RWCGP+VEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSA LDVPSLVEAAKQTAK+GAT Sbjct: 61 RWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSARLDVPSLVEAAKQTAKSGAT 120 Query: 130 EFCIVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHN 189 EFCIVAAVRGPDERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV++LA MGVHRYNHN Sbjct: 121 EFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVEQLAAMGVHRYNHN 180 Query: 190 LETARSFFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELN 249 LETARSFF NVVTTHTWEERW TL+MVR+AGMEVCCGGILGMGETLEQRAEFAA LAEL Sbjct: 181 LETARSFFTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLEQRAEFAAELAELG 240 Query: 250 PHEVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAK 309 P EVPLNFLNPRPGTPFGDLEVLP EALK+VAAFRLALPR MLRFAGGREITLGDLGAK Sbjct: 241 PDEVPLNFLNPRPGTPFGDLEVLPVPEALKSVAAFRLALPRAMLRFAGGREITLGDLGAK 300 Query: 310 KGILGGINAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 KGILGGINAVIVGNYLTTLGRPAEA MPIKALNATL Sbjct: 301 KGILGGINAVIVGNYLTTLGRPAEADLELLDDLQMPIKALNATL 344 >sp|B2HQ93|BIOB_MYCMM Tax_Id=216594 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium marinum] Length = 349 Score = 573 bits (1478), Expect = e-162 Identities = 285/341 (83%), Positives = 311/341 (91%), Gaps = 5/341 (1%) Query: 13 EDGVTQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWC 72 +DGVT+ D+L VAR+QVLERG GL+Q Q LQVLQL ++RL++LL+LAH+VRMRWC Sbjct: 14 QDGVTEP-----DILAVARQQVLERGEGLNQEQVLQVLQLSEDRLEELLALAHDVRMRWC 68 Query: 73 GPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFC 132 GP+VEVEGIISLKTGGCPEDCHFCSQSGLF+SPVRSAWLD+PSLVEAAKQTAK+GATEFC Sbjct: 69 GPEVEVEGIISLKTGGCPEDCHFCSQSGLFSSPVRSAWLDIPSLVEAAKQTAKSGATEFC 128 Query: 133 IVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLET 192 IVAAVRGPD RLL+QVAAGIEAIRNEV+I +ACSLGMLT EQV++LA MGVHRYNHNLET Sbjct: 129 IVAAVRGPDARLLSQVAAGIEAIRNEVEINVACSLGMLTAEQVEQLAAMGVHRYNHNLET 188 Query: 193 ARSFFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHE 252 ARS+F NVVTTHTWEERW TL MVR+AGMEVCCGGILGMGETLEQRAEFAANLAEL+P E Sbjct: 189 ARSYFTNVVTTHTWEERWQTLTMVRDAGMEVCCGGILGMGETLEQRAEFAANLAELDPDE 248 Query: 253 VPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGI 312 VPLNFLNPRPGTPFGDLEVLPA EALKAV AFRLALPRTMLRFAGGREITLGDLGAK+GI Sbjct: 249 VPLNFLNPRPGTPFGDLEVLPAGEALKAVGAFRLALPRTMLRFAGGREITLGDLGAKRGI 308 Query: 313 LGGINAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LGGINAVIVGNYLTTLGRPAEA MP+KALNA+L Sbjct: 309 LGGINAVIVGNYLTTLGRPAEADLELLEDLQMPLKALNASL 349 >sp|A0PP05|BIOB_MYCUA Tax_Id=362242 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium ulcerans] Length = 350 Score = 572 bits (1475), Expect = e-161 Identities = 285/341 (83%), Positives = 310/341 (90%), Gaps = 5/341 (1%) Query: 13 EDGVTQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWC 72 +DGVT+ D+L VAR+QVLERG GL+Q Q LQVLQL ++RL++LL LAH+VRMRWC Sbjct: 15 QDGVTEP-----DILAVARQQVLERGEGLNQEQVLQVLQLSEDRLEELLVLAHDVRMRWC 69 Query: 73 GPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFC 132 GP+VEVEGIISLKTGGCPEDCHFCSQSGLF+SPVRSAWLD+PSLVEAAKQTAK+GATEFC Sbjct: 70 GPEVEVEGIISLKTGGCPEDCHFCSQSGLFSSPVRSAWLDIPSLVEAAKQTAKSGATEFC 129 Query: 133 IVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLET 192 IVAAVRGPD RLL+QVAAGIEAIRNEV+I +ACSLGMLT EQV++LA MGVHRYNHNLET Sbjct: 130 IVAAVRGPDARLLSQVAAGIEAIRNEVEINVACSLGMLTAEQVEQLAAMGVHRYNHNLET 189 Query: 193 ARSFFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHE 252 ARS+F NVVTTHTWEERW TL MVR+AGMEVCCGGILGMGETLEQRAEFAANLAEL+P E Sbjct: 190 ARSYFTNVVTTHTWEERWQTLTMVRDAGMEVCCGGILGMGETLEQRAEFAANLAELDPDE 249 Query: 253 VPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGI 312 VPLNFLNPRPGTPFGDLEVLPA EALKAV AFRLALPRTMLRFAGGREITLGDLGAK+GI Sbjct: 250 VPLNFLNPRPGTPFGDLEVLPAGEALKAVGAFRLALPRTMLRFAGGREITLGDLGAKRGI 309 Query: 313 LGGINAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LGGINAVIVGNYLTTLGRPAEA MP+KALNA+L Sbjct: 310 LGGINAVIVGNYLTTLGRPAEADLELLEDLQMPLKALNASL 350 >sp|Q0SHW6|BIOB_RHOSR Tax_Id=101510 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Rhodococcus sp.] Length = 337 Score = 572 bits (1473), Expect = e-161 Identities = 281/330 (85%), Positives = 308/330 (93%) Query: 24 TDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIIS 83 TD+L +AREQVLERG L+++Q L+VLQLPD+RL++LL+LAH+VRM+WCGP+VEVEGIIS Sbjct: 8 TDILALAREQVLERGDALNESQVLEVLQLPDDRLEELLALAHDVRMKWCGPEVEVEGIIS 67 Query: 84 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 143 LKTGGCPEDCHFCSQSGLF SPVR+AWLD+PSLVEAAKQTAK+GA+EFCIVAAVRGPDER Sbjct: 68 LKTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGASEFCIVAAVRGPDER 127 Query: 144 LLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTT 203 LLAQVAAGIEAIRNEVDIQIACSLGMLT+EQV +LA MGVHRYNHNLET++S FPNVVTT Sbjct: 128 LLAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTT 187 Query: 204 HTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPG 263 HTW+ERW+TL MVREAGMEVCCGGILGMGE+LEQRAEFAANLAEL P EVPLNFLNPRPG Sbjct: 188 HTWDERWNTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPG 247 Query: 264 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 323 TPFGDLEVLPASEALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+GILGGINAVIVGN Sbjct: 248 TPFGDLEVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGN 307 Query: 324 YLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 YLTTLGRPAE MPIKALN TL Sbjct: 308 YLTTLGRPAEQDLDLLVDLQMPIKALNDTL 337 >tr|C1AU09|C1AU09_RHOOB Tax_Id=632772 (bioB)SubName: Full=Biotin synthase; EC=2.8.1.6;[Rhodococcus opacus] Length = 337 Score = 570 bits (1470), Expect = e-161 Identities = 281/330 (85%), Positives = 307/330 (93%) Query: 24 TDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIIS 83 TD+L +AREQVLERG L++AQ L+VLQLPD+RL++LL+LAH+VRM+WCGP+VEVEGIIS Sbjct: 8 TDILALAREQVLERGDALNEAQVLEVLQLPDDRLEELLALAHDVRMKWCGPEVEVEGIIS 67 Query: 84 LKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDER 143 LKTGGCPEDCHFCSQSGLF SPVR+AWLD+PSLVEAAKQTAK+GA+EFCIVAAVRGPDER Sbjct: 68 LKTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGASEFCIVAAVRGPDER 127 Query: 144 LLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTT 203 LLAQVAAGIEAIRNEVDIQIACSLGMLT+EQV +LA MGVHRYNHNLET++S FPNVVTT Sbjct: 128 LLAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTT 187 Query: 204 HTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPG 263 HTW+ERW+TL MVREAGMEVCCGGILGMGE+L QRAEFAANLAEL P EVPLNFLNPRPG Sbjct: 188 HTWDERWNTLRMVREAGMEVCCGGILGMGESLAQRAEFAANLAELEPDEVPLNFLNPRPG 247 Query: 264 TPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGN 323 TPFGDLEVLPASEALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+GILGGINAVIVGN Sbjct: 248 TPFGDLEVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGN 307 Query: 324 YLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 YLTTLGRPAE MPIKALN TL Sbjct: 308 YLTTLGRPAEQDLDLLVDLQMPIKALNDTL 337 >tr|C1A0R1|C1A0R1_RHOE4 Tax_Id=234621 (bioB)SubName: Full=Biotin synthase; EC=2.8.1.6;[Rhodococcus erythropolis] Length = 342 Score = 570 bits (1468), Expect = e-160 Identities = 281/329 (85%), Positives = 305/329 (92%) Query: 25 DVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIISL 84 D+LD AREQVLERGVGL ++Q L VL+L D+RL+DLL+LAH+VRM+WCGP+VEVEGIISL Sbjct: 14 DILDQAREQVLERGVGLTESQVLDVLRLDDDRLEDLLALAHDVRMKWCGPEVEVEGIISL 73 Query: 85 KTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDERL 144 KTGGCPEDCHFCSQSGLF SPVR+AWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD RL Sbjct: 74 KTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDARL 133 Query: 145 LAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTTH 204 LAQVAAGIEAIRNEVDIQIACSLGMLT+EQV +LA MGVHRYNHNLET++S FPNVVTTH Sbjct: 134 LAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTTH 193 Query: 205 TWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPGT 264 +WEERW+TL MVREAGMEVCCGGILGMGE+LEQRAEFAANLAEL P EVPLNFLNPRPGT Sbjct: 194 SWEERWNTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPGT 253 Query: 265 PFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGNY 324 PFGDL+VLPASEALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+GILGGINAVIVGNY Sbjct: 254 PFGDLDVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGNY 313 Query: 325 LTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LTTLGRPAE MPIKALN TL Sbjct: 314 LTTLGRPAEKDLDLLVDLQMPIKALNDTL 342 >tr|C3JIY2|C3JIY2_RHOER Tax_Id=596309 (bioB)SubName: Full=Biotin synthase; EC=2.8.1.6;[Rhodococcus erythropolis SK121] Length = 342 Score = 570 bits (1468), Expect = e-160 Identities = 281/329 (85%), Positives = 305/329 (92%) Query: 25 DVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIISL 84 D+LD AREQVLERGVGL ++Q L VL+L D+RL+DLL+LAH+VRM+WCGP+VEVEGIISL Sbjct: 14 DILDQAREQVLERGVGLTESQVLDVLRLDDDRLEDLLALAHDVRMKWCGPEVEVEGIISL 73 Query: 85 KTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDERL 144 KTGGCPEDCHFCSQSGLF SPVR+AWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD RL Sbjct: 74 KTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDARL 133 Query: 145 LAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTTH 204 LAQVAAGIEAIRNEVDIQIACSLGMLT+EQV +LA MGVHRYNHNLET++S FPNVVTTH Sbjct: 134 LAQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLAAMGVHRYNHNLETSKSHFPNVVTTH 193 Query: 205 TWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPGT 264 +WEERW+TL MVREAGMEVCCGGILGMGE+LEQRAEFAANLAEL P EVPLNFLNPRPGT Sbjct: 194 SWEERWNTLRMVREAGMEVCCGGILGMGESLEQRAEFAANLAELEPDEVPLNFLNPRPGT 253 Query: 265 PFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGNY 324 PFGDL+VLPASEALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+GILGGINAVIVGNY Sbjct: 254 PFGDLDVLPASEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGNY 313 Query: 325 LTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LTTLGRPAE MPIKALN TL Sbjct: 314 LTTLGRPAEKDLDLLVDLQMPIKALNDTL 342 >sp|P0A506|BIOB_MYCTU Tax_Id=1773 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium tuberculosis] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >sp|A5WMR0|BIOB_MYCTF Tax_Id=336982 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium tuberculosis] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >sp|A5U2U5|BIOB_MYCTA Tax_Id=419947 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium tuberculosis] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >sp|A1KJ05|BIOB_MYCBP Tax_Id=410289 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium bovis] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >sp|P0A507|BIOB_MYCBO Tax_Id=1765 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium bovis] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D0LA15|D0LA15_GORB4 Tax_Id=526226 SubName: Full=Biotin synthase; EC=2.8.1.6;[Gordonia bronchialis] Length = 345 Score = 569 bits (1467), Expect = e-160 Identities = 287/345 (83%), Positives = 309/345 (89%), Gaps = 7/345 (2%) Query: 16 VTQAAI-NGT------DVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVR 68 +TQA + +GT D+L VAR QVLERG LD+ Q L VL+LPD+RL +LL LAH+VR Sbjct: 1 MTQATVASGTVVTESDDILAVARAQVLERGEALDRDQVLTVLRLPDDRLTELLQLAHDVR 60 Query: 69 MRWCGPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGA 128 MRWCGP+VEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAW+D+PSLVEAAKQTAKTGA Sbjct: 61 MRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWIDIPSLVEAAKQTAKTGA 120 Query: 129 TEFCIVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNH 188 TEFCIVAAVRGPD+RLL+QVAAGIEAIRNEVDIQIACSLGMLT+EQV +L DMGVHRYNH Sbjct: 121 TEFCIVAAVRGPDKRLLSQVAAGIEAIRNEVDIQIACSLGMLTQEQVDQLRDMGVHRYNH 180 Query: 189 NLETARSFFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAEL 248 NLETARS FPNVVTTHTWEERWDTL MVR+AGMEVCCGGILGMGE+LEQRAEFAA+LA L Sbjct: 181 NLETARSHFPNVVTTHTWEERWDTLRMVRDAGMEVCCGGILGMGESLEQRAEFAADLASL 240 Query: 249 NPHEVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGA 308 P EVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRT+LRFAGGREITLGDLGA Sbjct: 241 EPDEVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTILRFAGGREITLGDLGA 300 Query: 309 KKGILGGINAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 K+GILGGINAVIVGNYLTTLGRPAE MPIK LN T+ Sbjct: 301 KQGILGGINAVIVGNYLTTLGRPAEDDLDLLSDLSMPIKTLNDTI 345 >tr|C6DSL9|C6DSL9_MYCTK Tax_Id=478434 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|C1ANL1|C1ANL1_MYCBT Tax_Id=561275 (bioB)SubName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium bovis] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D6G8R2|D6G8R2_MYCTU Tax_Id=478435 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis KZN 605] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D6FTB1|D6FTB1_MYCTU Tax_Id=611304 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis K85] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D6FH98|D6FH98_MYCTU Tax_Id=611303 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis CPHL_A] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D6F8V1|D6F8V1_MYCTU Tax_Id=611302 SubName: Full=Biotin synthase;[Mycobacterium tuberculosis T46] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D5ZG31|D5ZG31_MYCTU Tax_Id=537210 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis T17] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D5Z468|D5Z468_MYCTU Tax_Id=537209 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis GM 1503] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D5YF96|D5YF96_MYCTU Tax_Id=520140 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis EAS054] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D5Y3N3|D5Y3N3_MYCTU Tax_Id=520141 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis T85] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D5XWW4|D5XWW4_MYCTU Tax_Id=515617 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis T92] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|A4KHB4|A4KHB4_MYCTU Tax_Id=395095 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis str. Haarlem] Length = 365 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 34 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 93 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 94 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 153 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 154 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 213 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 214 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 273 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 274 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 333 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 334 GNYLTTLGRPAEADLELLDELQMPLKALNASL 365 >tr|A2VI81|A2VI81_MYCTU Tax_Id=348776 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis C] Length = 349 Score = 569 bits (1467), Expect = e-160 Identities = 281/332 (84%), Positives = 304/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRMRWCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D5YTF8|D5YTF8_MYCTU Tax_Id=515616 SubName: Full=Biotin synthetase bioB;[Mycobacterium tuberculosis 02_1987] Length = 349 Score = 567 bits (1460), Expect = e-159 Identities = 280/332 (84%), Positives = 303/332 (91%) Query: 22 NGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGI 81 N +D+L VAR+QVL+RG GL+Q Q L VLQLPD+RL++LL+LAHEVRM WCGP+VEVEGI Sbjct: 18 NNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMGWCGPEVEVEGI 77 Query: 82 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPD 141 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLD+PSLVEAAKQTAK+GATEFCIVAAVRGPD Sbjct: 78 ISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPD 137 Query: 142 ERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVV 201 ERL+AQVAAGIEAIRNEV+I IACSLGMLT EQV +LA GVHRYNHNLETARSFF NVV Sbjct: 138 ERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVV 197 Query: 202 TTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPR 261 TTHTWEERW TL+MVR+AGMEVCCGGILGMGETL+QRAEFAA LAEL P EVPLNFLNPR Sbjct: 198 TTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPR 257 Query: 262 PGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIV 321 PGTPF DLEV+P +ALKAVAAFRLALPRTMLRFAGGREITLGDLGAK+GILGGINAVIV Sbjct: 258 PGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIV 317 Query: 322 GNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 GNYLTTLGRPAEA MP+KALNA+L Sbjct: 318 GNYLTTLGRPAEADLELLDELQMPLKALNASL 349 >tr|D5PNW2|D5PNW2_COREQ Tax_Id=525370 (bioB)SubName: Full=Biotin synthase; EC=2.8.1.6;[Rhodococcus equi ATCC 33707] Length = 366 Score = 567 bits (1460), Expect = e-159 Identities = 282/344 (81%), Positives = 309/344 (89%), Gaps = 1/344 (0%) Query: 11 PQEDGVTQAA-INGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRM 69 P+E VT A + D+L AREQVLERG L+Q Q L+VL+L D+RL++LL+LAH+VRM Sbjct: 23 PEEFAVTSAPDVLDLDILAAAREQVLERGEALNQEQVLEVLRLGDDRLEELLALAHDVRM 82 Query: 70 RWCGPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGAT 129 +WCGP+VEVEGIISLKTGGCPEDCHFCSQSGLF SPVR+AWLD+PSLVEAAKQTAKTGAT Sbjct: 83 KWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFQSPVRAAWLDIPSLVEAAKQTAKTGAT 142 Query: 130 EFCIVAAVRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHN 189 EFCIVAAVRGPDE+LLAQVAAGIEAIRNEVDIQIACSLGMLT+EQV +LA MGVHRYNHN Sbjct: 143 EFCIVAAVRGPDEKLLAQVAAGIEAIRNEVDIQIACSLGMLTQEQVNQLAAMGVHRYNHN 202 Query: 190 LETARSFFPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELN 249 LETA S+F NVVTTHTWEERWDTL MVREAGMEVCCGGILGMGE++EQRAEFAANLA L Sbjct: 203 LETAESYFANVVTTHTWEERWDTLRMVREAGMEVCCGGILGMGESVEQRAEFAANLAALE 262 Query: 250 PHEVPLNFLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAK 309 P EVPLNF NPRPGTPFGDL+VLPA EALK+VAAFRLALPRT+LRFAGGREITLGDLGAK Sbjct: 263 PDEVPLNFFNPRPGTPFGDLDVLPAGEALKSVAAFRLALPRTILRFAGGREITLGDLGAK 322 Query: 310 KGILGGINAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 +G+LGGINAVIVGNYLTTLGRPAE+ MPIKALNATL Sbjct: 323 QGMLGGINAVIVGNYLTTLGRPAESDLDLLVDLEMPIKALNATL 366 >sp|P46715|BIOB_MYCLE Tax_Id=1769 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium leprae] Length = 345 Score = 553 bits (1426), Expect = e-155 Identities = 273/337 (81%), Positives = 302/337 (89%) Query: 17 TQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDV 76 T TD+L AR+QVLERG GL + Q LQ+L LPD+RL++LL+LAH+VRMRWCGP+V Sbjct: 9 TNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEV 68 Query: 77 EVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAA 136 E+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLD+ SLVEAAKQTAK+GATEFCIVAA Sbjct: 69 EIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAA 128 Query: 137 VRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSF 196 VRGPDERL++QVAAGIEAIRNEV+I IACSLGMLT EQV++L+ +GVHRYNHNLETARSF Sbjct: 129 VRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSF 188 Query: 197 FPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLN 256 F NVVTTHTWEERW TL+MVR+AGMEVCCGGILGMGET+EQRAEFA LAEL P EVPLN Sbjct: 189 FTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLN 248 Query: 257 FLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGI 316 FLNPRPGTPFG LEV+P SEALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+G+LGGI Sbjct: 249 FLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGI 308 Query: 317 NAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 NAVIVGNYLTTLGRPAEA MPIKALNA+L Sbjct: 309 NAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345 >sp|B8ZR86|BIOB_MYCLB Tax_Id=561304 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Mycobacterium leprae] Length = 345 Score = 553 bits (1426), Expect = e-155 Identities = 273/337 (81%), Positives = 302/337 (89%) Query: 17 TQAAINGTDVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDV 76 T TD+L AR+QVLERG GL + Q LQ+L LPD+RL++LL+LAH+VRMRWCGP+V Sbjct: 9 TNGDTENTDILAQARQQVLERGEGLSRDQVLQMLWLPDDRLEELLALAHDVRMRWCGPEV 68 Query: 77 EVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAA 136 E+EGIISLKTGGCPEDCHFCSQSGLF SPVRSAWLD+ SLVEAAKQTAK+GATEFCIVAA Sbjct: 69 EIEGIISLKTGGCPEDCHFCSQSGLFMSPVRSAWLDIRSLVEAAKQTAKSGATEFCIVAA 128 Query: 137 VRGPDERLLAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSF 196 VRGPDERL++QVAAGIEAIRNEV+I IACSLGMLT EQV++L+ +GVHRYNHNLETARSF Sbjct: 129 VRGPDERLMSQVAAGIEAIRNEVEINIACSLGMLTVEQVEQLSGIGVHRYNHNLETARSF 188 Query: 197 FPNVVTTHTWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLN 256 F NVVTTHTWEERW TL+MVR+AGMEVCCGGILGMGET+EQRAEFA LAEL P EVPLN Sbjct: 189 FTNVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETVEQRAEFALELAELGPDEVPLN 248 Query: 257 FLNPRPGTPFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGI 316 FLNPRPGTPFG LEV+P SEALK+VAAFRLALPRT+LRFAGGREITLGDLGAK+G+LGGI Sbjct: 249 FLNPRPGTPFGALEVMPPSEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGMLGGI 308 Query: 317 NAVIVGNYLTTLGRPAEAXXXXXXXXXMPIKALNATL 353 NAVIVGNYLTTLGRPAEA MPIKALNA+L Sbjct: 309 NAVIVGNYLTTLGRPAEADLRLLDDLQMPIKALNASL 345 >tr|C4REH6|C4REH6_9ACTO Tax_Id=219305 SubName: Full=Biotin synthase;[Micromonospora sp. ATCC 39149] Length = 331 Score = 523 bits (1348), Expect = e-146 Identities = 253/329 (76%), Positives = 284/329 (86%) Query: 25 DVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIISL 84 ++LD AR QVLE GVGLDQA L VL+LPDE L L LAHEVRMRWCGP+VEVEGI+SL Sbjct: 3 EILDQARTQVLESGVGLDQAGVLAVLKLPDEHLPAALQLAHEVRMRWCGPEVEVEGIVSL 62 Query: 85 KTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDERL 144 KTGGCPEDCHFCSQSGLFASPVRS WLD+PSLVEAAKQTA TGATEFCIVAAVRGPD RL Sbjct: 63 KTGGCPEDCHFCSQSGLFASPVRSVWLDIPSLVEAAKQTAATGATEFCIVAAVRGPDARL 122 Query: 145 LAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTTH 204 + Q+ G+ AIR EVDIQ+A SLGML++EQV L DMGVHRYNHNLET RS+FPNVVTTH Sbjct: 123 MKQMREGVAAIRAEVDIQVAASLGMLSQEQVDELVDMGVHRYNHNLETCRSYFPNVVTTH 182 Query: 205 TWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPGT 264 +WEERW+TL MVRE+GMEVCCGGILG+GE++EQRAEFAA LAEL+PHEVPLNFLNPRPGT Sbjct: 183 SWEERWETLRMVRESGMEVCCGGILGLGESVEQRAEFAAQLAELDPHEVPLNFLNPRPGT 242 Query: 265 PFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGNY 324 P GD V+ +AL+A+AAFRLA+PRT+LR+AGGREITLGDLG + G+LGGINAVIVGNY Sbjct: 243 PLGDRPVVEGKDALRAIAAFRLAMPRTILRYAGGREITLGDLGTRDGLLGGINAVIVGNY 302 Query: 325 LTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LTTLGRPA MP+KAL+ATL Sbjct: 303 LTTLGRPATDDLALLTELKMPVKALSATL 331 >sp|A4X585|BIOB_SALTO Tax_Id=369723 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Salinispora tropica] Length = 331 Score = 521 bits (1342), Expect = e-146 Identities = 248/329 (75%), Positives = 284/329 (86%) Query: 25 DVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIISL 84 ++LD AR QVLE GVGLD+A L VL LPDE L L LAHEVRMRWCGP+VEVEGI+SL Sbjct: 3 EILDQARTQVLENGVGLDEAGVLAVLNLPDEHLPAALQLAHEVRMRWCGPEVEVEGIVSL 62 Query: 85 KTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDERL 144 KTGGCPEDCHFCSQSGLF SPVR+ WLD+PSLVEAAKQTAKTGATEFCIVAAVRGPD+RL Sbjct: 63 KTGGCPEDCHFCSQSGLFTSPVRAVWLDIPSLVEAAKQTAKTGATEFCIVAAVRGPDDRL 122 Query: 145 LAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTTH 204 + Q+ G+ AI+ EVDIQ+A S+GMLT+EQV L +MGVHRYNHNLET RS+FPNVVTTH Sbjct: 123 MRQLREGVAAIQAEVDIQVAASVGMLTQEQVDELVEMGVHRYNHNLETCRSYFPNVVTTH 182 Query: 205 TWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPGT 264 +WEERW+TL MVRE+GMEVCCGGILG+GE++EQRAEFAA LAEL+PHEVPLNFLNPRPGT Sbjct: 183 SWEERWETLRMVRESGMEVCCGGILGLGESVEQRAEFAAQLAELDPHEVPLNFLNPRPGT 242 Query: 265 PFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGNY 324 P GD V+ +AL+A+AAFRLA+PRT+LR+AGGRE+TLGDLG + G+LGGINAVIVGNY Sbjct: 243 PLGDRSVVEGKDALRAIAAFRLAMPRTILRYAGGRELTLGDLGTRSGLLGGINAVIVGNY 302 Query: 325 LTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LTTLGRPA MP+KAL+ATL Sbjct: 303 LTTLGRPATTDLELLEDLKMPVKALSATL 331 >sp|A8LUR1|BIOB_SALAI Tax_Id=391037 (bioB)RecName: Full=Biotin synthase; EC=2.8.1.6;[Salinispora arenicola] Length = 331 Score = 520 bits (1340), Expect = e-146 Identities = 249/329 (75%), Positives = 282/329 (85%) Query: 25 DVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIISL 84 ++LD AR QVLE GVGLD+A L VL LPDE L L LAHEVRMRWCGP+VEVEGI+SL Sbjct: 3 EILDQARTQVLENGVGLDEAGALAVLNLPDEHLPAALQLAHEVRMRWCGPEVEVEGIVSL 62 Query: 85 KTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDERL 144 KTGGCPEDCHFCSQSGLF SPVR+ WLD+PSLVEAAKQTAKTGATEFCIVAAVRGPD+RL Sbjct: 63 KTGGCPEDCHFCSQSGLFTSPVRAVWLDIPSLVEAAKQTAKTGATEFCIVAAVRGPDDRL 122 Query: 145 LAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTTH 204 + Q+ G+ AIR EVDI +A S+GMLT+EQV L +MGVHRYNHNLET RS+FPNVVTTH Sbjct: 123 MRQLREGVAAIRAEVDIHVAASVGMLTQEQVDELVEMGVHRYNHNLETCRSYFPNVVTTH 182 Query: 205 TWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPGT 264 +WEERW+TL MVR +GMEVCCGGILG+GET+EQRAEFAA LAEL+PHEVPLNFLNPRPGT Sbjct: 183 SWEERWETLRMVRASGMEVCCGGILGLGETVEQRAEFAAQLAELDPHEVPLNFLNPRPGT 242 Query: 265 PFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGNY 324 P GD V+ +AL+A+AAFRLA+PRT+LR+AGGREITLGDLG + G+LGGINAVIVGNY Sbjct: 243 PLGDRPVVEGKDALRAIAAFRLAMPRTILRYAGGREITLGDLGTRSGLLGGINAVIVGNY 302 Query: 325 LTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LTTLGRPA MP+KAL+ATL Sbjct: 303 LTTLGRPATTDLELLDDLKMPVKALSATL 331 >tr|D1S9H1|D1S9H1_9ACTO Tax_Id=644283 SubName: Full=Biotin synthase; EC=2.8.1.6;[Micromonospora aurantiaca ATCC 27029] Length = 331 Score = 518 bits (1334), Expect = e-145 Identities = 249/329 (75%), Positives = 282/329 (85%) Query: 25 DVLDVAREQVLERGVGLDQAQTLQVLQLPDERLDDLLSLAHEVRMRWCGPDVEVEGIISL 84 ++LD ARE+VL GVGLD+A L VL LPDE L L LAHEVRMRWCGP+VEVEGI+SL Sbjct: 3 EILDQARERVLGNGVGLDEAGVLAVLNLPDEHLPAALQLAHEVRMRWCGPEVEVEGIVSL 62 Query: 85 KTGGCPEDCHFCSQSGLFASPVRSAWLDVPSLVEAAKQTAKTGATEFCIVAAVRGPDERL 144 KTGGCPEDCHFCSQSGLF SPVRS WLD+P+LVEAAKQTA TGATEFCIVAAVRGPD RL Sbjct: 63 KTGGCPEDCHFCSQSGLFTSPVRSVWLDIPALVEAAKQTAATGATEFCIVAAVRGPDARL 122 Query: 145 LAQVAAGIEAIRNEVDIQIACSLGMLTEEQVQRLADMGVHRYNHNLETARSFFPNVVTTH 204 + Q+ G+ AIR VDIQ+A SLGMLT+EQV L +MGVHRYNHNLET RS+FPNVVTTH Sbjct: 123 MKQMREGVAAIRAAVDIQVAASLGMLTKEQVDELVEMGVHRYNHNLETCRSYFPNVVTTH 182 Query: 205 TWEERWDTLNMVREAGMEVCCGGILGMGETLEQRAEFAANLAELNPHEVPLNFLNPRPGT 264 +WEERW+TL MVRE+GMEVCCGGILG+GET+EQRAEFAA LAEL+PHEVPLNFLNPRPGT Sbjct: 183 SWEERWETLRMVRESGMEVCCGGILGLGETVEQRAEFAAQLAELDPHEVPLNFLNPRPGT 242 Query: 265 PFGDLEVLPASEALKAVAAFRLALPRTMLRFAGGREITLGDLGAKKGILGGINAVIVGNY 324 P GD V+ +AL+A+AAFRLA+PRT+LR+AGGRE+TLGDLG + G+LGGINAVIVGNY Sbjct: 243 PLGDRPVVEGKDALRAIAAFRLAMPRTILRYAGGRELTLGDLGTRDGLLGGINAVIVGNY 302 Query: 325 LTTLGRPAEAXXXXXXXXXMPIKALNATL 353 LTTLGRPA A MP+KAL+ATL Sbjct: 303 LTTLGRPATADLKLLEDLKMPVKALSATL 331 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.320 0.136 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 2,792,313,973 Number of extensions: 116183911 Number of successful extensions: 306147 Number of sequences better than 10.0: 2221 Number of HSP's gapped: 304039 Number of HSP's successfully gapped: 2222 Length of query: 353 Length of database: 4,236,830,644 Length adjustment: 139 Effective length of query: 214 Effective length of database: 2,498,237,548 Effective search space: 534622835272 Effective search space used: 534622835272 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 81 (35.8 bits)