BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_3666 (307 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|A0QYI1|A0QYI1_MYCS2 Tax_Id=246196 SubName: Full=C-5 sterol de... 597 e-169 tr|Q1B813|Q1B813_MYCSS Tax_Id=164756 SubName: Full=Sterol desatu... 459 e-127 tr|A1UGZ4|A1UGZ4_MYCSK Tax_Id=189918 SubName: Full=Sterol desatu... 459 e-127 tr|A3Q0J6|A3Q0J6_MYCSJ Tax_Id=164757 SubName: Full=Sterol desatu... 458 e-127 tr|A1T9X3|A1T9X3_MYCVP Tax_Id=350058 SubName: Full=Sterol desatu... 446 e-123 tr|A0QGQ0|A0QGQ0_MYCA1 Tax_Id=243243 SubName: Full=C-5 sterol de... 439 e-121 tr|A4TA71|A4TA71_MYCGI Tax_Id=350054 SubName: Full=Sterol desatu... 436 e-120 tr|D5P3Q5|D5P3Q5_9MYCO Tax_Id=525368 SubName: Full=C-5 sterol de... 434 e-120 tr|Q73ZS6|Q73ZS6_MYCPA Tax_Id=1770 SubName: Full=Putative unchar... 428 e-118 tr|C6DR67|C6DR67_MYCTK Tax_Id=478434 SubName: Full=Membrane-boun... 426 e-117 tr|A5WNE0|A5WNE0_MYCTF Tax_Id=336982 SubName: Full=Membrane-boun... 426 e-117 tr|D5YST8|D5YST8_MYCTU Tax_Id=515616 SubName: Full=Membrane-boun... 426 e-117 tr|A4KHW6|A4KHW6_MYCTU Tax_Id=395095 SubName: Full=Membrane-boun... 426 e-117 tr|A2VIT4|A2VIT4_MYCTU Tax_Id=348776 SubName: Full=Membrane-boun... 426 e-117 tr|D6G7J6|D6G7J6_MYCTU Tax_Id=478435 SubName: Full=Membrane-boun... 422 e-116 sp|P68435|ERG3_MYCTU Tax_Id=1773 (erg3)RecName: Full=C-5 sterol ... 419 e-115 sp|P68434|ERG3_MYCBO Tax_Id=1765 (erg3)RecName: Full=C-5 sterol ... 419 e-115 tr|C1AP90|C1AP90_MYCBT Tax_Id=561275 (erg3)SubName: Full=Membran... 419 e-115 tr|A5U3I1|A5U3I1_MYCTA Tax_Id=419947 (erg3)SubName: Full=Sterol ... 419 e-115 tr|A1KJM5|A1KJM5_MYCBP Tax_Id=410289 (erg3)SubName: Full=Membran... 419 e-115 tr|A0PSJ3|A0PSJ3_MYCUA Tax_Id=362242 (erg3)SubName: Full=Membran... 419 e-115 tr|D6FUQ7|D6FUQ7_MYCTU Tax_Id=611304 SubName: Full=Membrane-boun... 419 e-115 tr|D6FB30|D6FB30_MYCTU Tax_Id=611303 SubName: Full=Membrane-boun... 419 e-115 tr|D6F4R2|D6F4R2_MYCTU Tax_Id=611302 SubName: Full=Membrane-boun... 419 e-115 tr|D5ZHY1|D5ZHY1_MYCTU Tax_Id=537210 SubName: Full=Membrane-boun... 419 e-115 tr|D5Z2X5|D5Z2X5_MYCTU Tax_Id=537209 SubName: Full=Membrane-boun... 419 e-115 tr|D5YFY0|D5YFY0_MYCTU Tax_Id=520140 SubName: Full=Membrane-boun... 419 e-115 tr|D5Y4A9|D5Y4A9_MYCTU Tax_Id=520141 SubName: Full=Membrane-boun... 419 e-115 tr|D5XUB3|D5XUB3_MYCTU Tax_Id=515617 SubName: Full=Membrane-boun... 419 e-115 tr|B2HSW0|B2HSW0_MYCMM Tax_Id=216594 (erg3)SubName: Full=Membran... 414 e-113 tr|D5PKQ2|D5PKQ2_COREQ Tax_Id=525370 SubName: Full=C-5 sterol de... 405 e-111 tr|C1B9I3|C1B9I3_RHOOB Tax_Id=632772 SubName: Full=Hypothetical ... 402 e-110 tr|C0ZM67|C0ZM67_RHOE4 Tax_Id=234621 SubName: Full=Conserved hyp... 393 e-107 tr|C3JQ25|C3JQ25_RHOER Tax_Id=596309 SubName: Full=C-5 sterol de... 392 e-107 tr|D0L9B3|D0L9B3_GORB4 Tax_Id=526226 SubName: Full=Fatty acid hy... 386 e-105 tr|B2HF71|B2HF71_MYCMM Tax_Id=216594 (erg3_1)SubName: Full=Membr... 363 1e-98 tr|Q0S934|Q0S934_RHOSR Tax_Id=101510 SubName: Full=Probable C-5 ... 342 4e-92 tr|D6B816|D6B816_9ACTO Tax_Id=457425 SubName: Full=C-5 sterol de... 320 1e-85 tr|A3TFN1|A3TFN1_9MICO Tax_Id=313589 SubName: Full=Putative unch... 306 2e-81 tr|D4SHA0|D4SHA0_9ACTO Tax_Id=585531 SubName: Full=C-5 sterol de... 303 1e-80 tr|D3CKC9|D3CKC9_9ACTO Tax_Id=648999 SubName: Full=Fatty acid hy... 276 3e-72 tr|D1S248|D1S248_9ACTO Tax_Id=644283 SubName: Full=Fatty acid hy... 275 5e-72 tr|Q5YZB6|Q5YZB6_NOCFA Tax_Id=37329 SubName: Full=Putative uncha... 261 6e-68 tr|D3F644|D3F644_CONWI Tax_Id=469383 SubName: Full=Fatty acid hy... 259 3e-67 tr|D1WX07|D1WX07_9ACTO Tax_Id=649189 SubName: Full=Fatty acid hy... 254 7e-66 >tr|A0QYI1|A0QYI1_MYCS2 Tax_Id=246196 SubName: Full=C-5 sterol desaturase; EC=1.3.-.-;[Mycobacterium smegmatis] Length = 307 Score = 597 bits (1538), Expect = e-169 Identities = 282/307 (91%), Positives = 282/307 (91%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRD 60 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRD Sbjct: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRD 60 Query: 61 AWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTY 120 AWTSVSMGLVSVATTAGWK PWQLPADKWYTWVIALLGVDLLWYTY Sbjct: 61 AWTSVSMGLVSVATTAGWKLLALLGYAVLYAYVAPWQLPADKWYTWVIALLGVDLLWYTY 120 Query: 121 HRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFS 180 HRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAW WVVFAAFS Sbjct: 121 HRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWIPLPLLGIPPWVVFAAFS 180 Query: 181 VNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTF 240 VNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTF Sbjct: 181 VNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTF 240 Query: 241 QEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTC 300 QEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTC Sbjct: 241 QEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTC 300 Query: 301 ETTEVTT 307 ETTEVTT Sbjct: 301 ETTEVTT 307 >tr|Q1B813|Q1B813_MYCSS Tax_Id=164756 SubName: Full=Sterol desaturase-related protein;[Mycobacterium sp.] Length = 312 Score = 459 bits (1181), Expect = e-127 Identities = 208/303 (68%), Positives = 241/303 (79%), Gaps = 2/303 (0%) Query: 2 DTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDA 61 + + + L+FLPP +R+PV+FA+PFFLLLL +EWTAAR+LEH++ GD+ PAGA+ RDA Sbjct: 6 EAVSAFLQFLPPQLREPVLFAVPFFLLLLILEWTAARKLEHLE--SGDQPPAGAYVARDA 63 Query: 62 WTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYH 121 WTS++MGLVSV T A WK PWQLP+++WYTWVIA++GVDLL+Y+YH Sbjct: 64 WTSLAMGLVSVGTMAVWKFGALIGYAALYAYVAPWQLPSNQWYTWVIAIVGVDLLFYSYH 123 Query: 122 RVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSV 181 R+AHRVRL+WATHQAHHSSEY+NFATALRQKWNNSGEIV W W+VFA FS+ Sbjct: 124 RIAHRVRLVWATHQAHHSSEYYNFATALRQKWNNSGEIVMWLPLPLLGVPPWMVFAGFSI 183 Query: 182 NLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQ 241 +LIYQFWVHTERIG + RPIEFVFNTPSHHRVHHG D YLD+NYGGILIIWDRLFGTFQ Sbjct: 184 SLIYQFWVHTERIGTMWRPIEFVFNTPSHHRVHHGRDPEYLDKNYGGILIIWDRLFGTFQ 243 Query: 242 EEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTCE 301 E+FRP YGLTKPV TYNIW+LQTHEY AIA DVR ARRW DRLGY FGPPGW P Sbjct: 244 PELFRPHYGLTKPVNTYNIWRLQTHEYAAIARDVRGARRWRDRLGYAFGPPGWKPVENRH 303 Query: 302 TTE 304 E Sbjct: 304 VAE 306 >tr|A1UGZ4|A1UGZ4_MYCSK Tax_Id=189918 SubName: Full=Sterol desaturase-related protein;[Mycobacterium sp.] Length = 312 Score = 459 bits (1181), Expect = e-127 Identities = 208/303 (68%), Positives = 241/303 (79%), Gaps = 2/303 (0%) Query: 2 DTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDA 61 + + + L+FLPP +R+PV+FA+PFFLLLL +EWTAAR+LEH++ GD+ PAGA+ RDA Sbjct: 6 EAVSAFLQFLPPQLREPVLFAVPFFLLLLILEWTAARKLEHLE--SGDQPPAGAYVARDA 63 Query: 62 WTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYH 121 WTS++MGLVSV T A WK PWQLP+++WYTWVIA++GVDLL+Y+YH Sbjct: 64 WTSLAMGLVSVGTMAVWKFGALIGYAALYAYVAPWQLPSNQWYTWVIAIVGVDLLFYSYH 123 Query: 122 RVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSV 181 R+AHRVRL+WATHQAHHSSEY+NFATALRQKWNNSGEIV W W+VFA FS+ Sbjct: 124 RIAHRVRLVWATHQAHHSSEYYNFATALRQKWNNSGEIVMWLPLPLLGVPPWMVFAGFSI 183 Query: 182 NLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQ 241 +LIYQFWVHTERIG + RPIEFVFNTPSHHRVHHG D YLD+NYGGILIIWDRLFGTFQ Sbjct: 184 SLIYQFWVHTERIGTMWRPIEFVFNTPSHHRVHHGRDPEYLDKNYGGILIIWDRLFGTFQ 243 Query: 242 EEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTCE 301 E+FRP YGLTKPV TYNIW+LQTHEY AIA DVR ARRW DRLGY FGPPGW P Sbjct: 244 PELFRPHYGLTKPVNTYNIWRLQTHEYAAIARDVRGARRWRDRLGYAFGPPGWKPVENRH 303 Query: 302 TTE 304 E Sbjct: 304 VAE 306 >tr|A3Q0J6|A3Q0J6_MYCSJ Tax_Id=164757 SubName: Full=Sterol desaturase-related protein;[Mycobacterium sp.] Length = 312 Score = 458 bits (1178), Expect = e-127 Identities = 207/303 (68%), Positives = 241/303 (79%), Gaps = 2/303 (0%) Query: 2 DTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDA 61 + + + L+FLPP +R+PV+FA+PFFLLLL +EWTAAR+LEH++ GD+ PAGA+ RDA Sbjct: 6 EAVSAFLQFLPPQLREPVLFAVPFFLLLLILEWTAARKLEHLE--SGDQPPAGAYVARDA 63 Query: 62 WTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYH 121 WTS++MGLVSV T A WK PWQLP+++WYTWVIA++GVDLL+Y+YH Sbjct: 64 WTSLAMGLVSVGTMAVWKFGALIGYAALYAYVAPWQLPSNQWYTWVIAIVGVDLLFYSYH 123 Query: 122 RVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSV 181 R+AHRVRL+WATHQAHHSSEY+NFATA+RQKWNNSGEIV W W+VFA FS+ Sbjct: 124 RIAHRVRLVWATHQAHHSSEYYNFATAVRQKWNNSGEIVMWLPLPLLGVPPWMVFAGFSI 183 Query: 182 NLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQ 241 +LIYQFWVHTERIG + RPIEFVFNTPSHHRVHHG D YLD+NYGGILIIWDRLFGTFQ Sbjct: 184 SLIYQFWVHTERIGTMWRPIEFVFNTPSHHRVHHGRDPEYLDKNYGGILIIWDRLFGTFQ 243 Query: 242 EEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTCE 301 E+FRP YGLTKPV TYNIW+LQTHEY AIA DVR ARRW DRLGY FGPPGW P Sbjct: 244 PELFRPHYGLTKPVNTYNIWRLQTHEYAAIARDVRGARRWRDRLGYAFGPPGWKPVENRH 303 Query: 302 TTE 304 E Sbjct: 304 VAE 306 >tr|A1T9X3|A1T9X3_MYCVP Tax_Id=350058 SubName: Full=Sterol desaturase-related protein;[Mycobacterium vanbaalenii] Length = 305 Score = 446 bits (1146), Expect = e-123 Identities = 206/290 (71%), Positives = 232/290 (80%), Gaps = 1/290 (0%) Query: 8 LEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDAWTSVSM 67 L+FLPP MR+PV+FAIPFFLLLLTIEWTAAR+LEH P G A GA+HTRD+W SVSM Sbjct: 4 LDFLPPQMREPVLFAIPFFLLLLTIEWTAARKLEHTAPDGGSPA-VGAYHTRDSWASVSM 62 Query: 68 GLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRV 127 GLVS T + WK PWQL A +WYTWVIAL+GVDLL+Y YHR+AHRV Sbjct: 63 GLVSTVTMSVWKFLALLGYAALYAYVAPWQLSATQWYTWVIALVGVDLLFYVYHRMAHRV 122 Query: 128 RLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQF 187 R++WATHQAHHSS YFNFATALRQKWNNSGEI+ W W+VF AFSV+LIYQF Sbjct: 123 RIVWATHQAHHSSRYFNFATALRQKWNNSGEILMWIPLPLLGVPPWMVFFAFSVSLIYQF 182 Query: 188 WVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRP 247 W+HTERIGKL P+EF+FNTPSHHRVHHG D+LYLD+NYGGILIIWDRLFGTFQ EVFRP Sbjct: 183 WIHTERIGKLWLPVEFIFNTPSHHRVHHGMDKLYLDKNYGGILIIWDRLFGTFQPEVFRP 242 Query: 248 RYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPA 297 YGLTKPV T+NIWKLQTHEYVAI DVR+AR +LGY+FGPPGW P+ Sbjct: 243 HYGLTKPVDTFNIWKLQTHEYVAIGRDVRAARGLRAKLGYIFGPPGWEPS 292 >tr|A0QGQ0|A0QGQ0_MYCA1 Tax_Id=243243 SubName: Full=C-5 sterol desaturase; EC=1.3.-.-;[Mycobacterium avium] Length = 308 Score = 439 bits (1130), Expect = e-121 Identities = 209/310 (67%), Positives = 233/310 (75%), Gaps = 7/310 (2%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRD 60 M L L LPP +RDPV+ AIPFFLLLLT+EWTAAR+LEH+ R GA TRD Sbjct: 1 MSALSGYLTALPPQLRDPVLVAIPFFLLLLTLEWTAARKLEHLTA----RPAPGAHRTRD 56 Query: 61 AWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTY 120 + TS+SMGLVSVATTAGWK PW LPA +WYTW I +LGVDLL+Y Y Sbjct: 57 SLTSISMGLVSVATTAGWKTLALFGYAAIYAYLAPWHLPATRWYTWAIPILGVDLLYYAY 116 Query: 121 HRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFS 180 HR+AHRVRLIWATHQAHHSSEY+NFATALRQKWNNSGEI+ W W+VF +FS Sbjct: 117 HRIAHRVRLIWATHQAHHSSEYYNFATALRQKWNNSGEILMWIPLPLLGIPPWMVFFSFS 176 Query: 181 VNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTF 240 +NLIYQFW+HTERI KLPRP EFVFNTPSHHRVHHG D++YLD+NYGGILI+WDRLFGTF Sbjct: 177 LNLIYQFWIHTERIDKLPRPFEFVFNTPSHHRVHHGMDKVYLDKNYGGILIVWDRLFGTF 236 Query: 241 QEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP---A 297 Q E+FRP YGLTK V T+N+WKLQT EYVAIA D RSA R DRLGYVFGPPGW P Sbjct: 237 QAELFRPHYGLTKQVDTFNVWKLQTREYVAIARDWRSASRLRDRLGYVFGPPGWAPRSAG 296 Query: 298 RTCETTEVTT 307 RT V T Sbjct: 297 RTAAGAPVVT 306 >tr|A4TA71|A4TA71_MYCGI Tax_Id=350054 SubName: Full=Sterol desaturase-related protein;[Mycobacterium gilvum] Length = 306 Score = 436 bits (1120), Expect = e-120 Identities = 204/294 (69%), Positives = 228/294 (77%), Gaps = 3/294 (1%) Query: 8 LEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHV--DPAEGDRAPA-GAFHTRDAWTS 64 LEFLPP MR+PV+FAIPFFLLLL IEWTAAR+LEH A+ D PA GA+HTRD+W S Sbjct: 4 LEFLPPQMREPVLFAIPFFLLLLAIEWTAARKLEHAVEGGADEDGTPAAGAYHTRDSWAS 63 Query: 65 VSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVA 124 +SMGLVS T + WK PWQL +WYTWVIA++GVDLL+Y YHR A Sbjct: 64 LSMGLVSTVTMSVWKFFALLGYAAIYAYLAPWQLSPTQWYTWVIAIVGVDLLFYVYHRTA 123 Query: 125 HRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLI 184 HRVRL+WATHQAHHSS YFNFATALRQKWNNSGEI+ W W+VF AFS++LI Sbjct: 124 HRVRLVWATHQAHHSSRYFNFATALRQKWNNSGEILMWIPLPLLGVPPWMVFVAFSISLI 183 Query: 185 YQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEV 244 YQFW+HTE IGKL RP EFVFNTPSHHRVHHG D LYLD+NYGGILIIWDRLFGTFQ EV Sbjct: 184 YQFWIHTEHIGKLWRPFEFVFNTPSHHRVHHGMDPLYLDKNYGGILIIWDRLFGTFQPEV 243 Query: 245 FRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPAR 298 FRP YGLTKPV T+NIWKLQTHEY AI D R+AR +LGY+FGPPGW PA+ Sbjct: 244 FRPHYGLTKPVDTFNIWKLQTHEYAAIWRDARAARGVRAKLGYIFGPPGWQPAQ 297 >tr|D5P3Q5|D5P3Q5_9MYCO Tax_Id=525368 SubName: Full=C-5 sterol desaturase; EC=1.3.-.-;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 312 Score = 434 bits (1116), Expect = e-120 Identities = 205/299 (68%), Positives = 231/299 (77%), Gaps = 2/299 (0%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRD 60 + L + LPP MRDPV+ AIPFFLLLLT+EWTAAR+LE + + R +GA+ TRD Sbjct: 3 VSALSGFVSALPPQMRDPVLLAIPFFLLLLTLEWTAARKLESL--TKEARPVSGAYLTRD 60 Query: 61 AWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTY 120 + S+SMGLVSV TTA WK PW L A +WYTWVIAL+GVDLL+Y Y Sbjct: 61 SLASISMGLVSVGTTAAWKTLALFGYAALFAYVAPWHLSAARWYTWVIALVGVDLLYYAY 120 Query: 121 HRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFS 180 HR+AHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF +FS Sbjct: 121 HRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLLGIPPWMVFFSFS 180 Query: 181 VNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTF 240 ++LIYQFWVHTERI KLPRP EFVFNTPSHHRVHHG D+LYLD+NYGGILI+WDRLFG+F Sbjct: 181 ISLIYQFWVHTERIDKLPRPFEFVFNTPSHHRVHHGMDQLYLDKNYGGILILWDRLFGSF 240 Query: 241 QEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPART 299 Q E+FRP YGLTK V T+NIWKLQT EYVAIAHD RSA R DRLGYVFGPPGW P T Sbjct: 241 QAELFRPHYGLTKRVDTFNIWKLQTREYVAIAHDWRSATRLRDRLGYVFGPPGWAPRTT 299 >tr|Q73ZS6|Q73ZS6_MYCPA Tax_Id=1770 SubName: Full=Putative uncharacterized protein;[Mycobacterium paratuberculosis] Length = 294 Score = 428 bits (1100), Expect = e-118 Identities = 204/296 (68%), Positives = 226/296 (76%), Gaps = 7/296 (2%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDAWTSVSMGLVSVAT 74 MRDPV+ AIPFFLLLLT+EWTAAR+LEH+ R GA TRD+ TS+SMGLVSVAT Sbjct: 1 MRDPVLVAIPFFLLLLTLEWTAARKLEHLTA----RPAPGAHQTRDSLTSISMGLVSVAT 56 Query: 75 TAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWATH 134 TAGWK PW LPA +WYTW IA+LGVDLL+Y YHR+AHRVRLIWATH Sbjct: 57 TAGWKTLALFGYAAIYAYLAPWHLPATRWYTWAIAILGVDLLYYAYHRIAHRVRLIWATH 116 Query: 135 QAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTERI 194 QAHHSSEY+NFATALRQKWNNSGEI+ W W+VF +FSVNLIYQFW+HTERI Sbjct: 117 QAHHSSEYYNFATALRQKWNNSGEILMWLPLPLLGIPPWMVFFSFSVNLIYQFWIHTERI 176 Query: 195 GKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLTKP 254 KLPRP EFVFNTPSHHRVHHG D++YLD+NYGGILI+WDRLFGTFQ E+FRP YGLTK Sbjct: 177 DKLPRPFEFVFNTPSHHRVHHGMDKVYLDKNYGGILIVWDRLFGTFQAELFRPHYGLTKH 236 Query: 255 VGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP---ARTCETTEVTT 307 V T+N+W LQT E VAIA D RSA R DRLGYVFGPPGW P RT V T Sbjct: 237 VDTFNVWTLQTRESVAIARDWRSASRLRDRLGYVFGPPGWAPRSAGRTAAGAPVVT 292 >tr|C6DR67|C6DR67_MYCTK Tax_Id=478434 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis] Length = 314 Score = 426 bits (1094), Expect = e-117 Identities = 203/298 (68%), Positives = 230/298 (77%), Gaps = 2/298 (0%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHT 58 MD + LP MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ T Sbjct: 1 MDAVAGFFSALPEEMRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLT 60 Query: 59 RDAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWY 118 RD+ S+SMGLVS+ATTAGWK PWQL A +WYTWVIA++GVDLL+Y Sbjct: 61 RDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYY 120 Query: 119 TYHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAA 178 +YHR+AHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF + Sbjct: 121 SYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCS 180 Query: 179 FSVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFG 238 +S+NLIYQFWVHTERI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG Sbjct: 181 WSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFG 240 Query: 239 TFQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 +FQ E+FRP YGLTK V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 SFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 298 >tr|A5WNE0|A5WNE0_MYCTF Tax_Id=336982 SubName: Full=Membrane-bound C-5 sterol desaturase erg3 (Sterol-c5-desaturase);[Mycobacterium tuberculosis] Length = 314 Score = 426 bits (1094), Expect = e-117 Identities = 203/298 (68%), Positives = 230/298 (77%), Gaps = 2/298 (0%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHT 58 MD + LP MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ T Sbjct: 1 MDAVAGFFSALPEEMRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLT 60 Query: 59 RDAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWY 118 RD+ S+SMGLVS+ATTAGWK PWQL A +WYTWVIA++GVDLL+Y Sbjct: 61 RDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYY 120 Query: 119 TYHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAA 178 +YHR+AHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF + Sbjct: 121 SYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCS 180 Query: 179 FSVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFG 238 +S+NLIYQFWVHTERI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG Sbjct: 181 WSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFG 240 Query: 239 TFQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 +FQ E+FRP YGLTK V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 SFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 298 >tr|D5YST8|D5YST8_MYCTU Tax_Id=515616 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis 02_1987] Length = 314 Score = 426 bits (1094), Expect = e-117 Identities = 203/298 (68%), Positives = 230/298 (77%), Gaps = 2/298 (0%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHT 58 MD + LP MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ T Sbjct: 1 MDAVAGFFSALPEEMRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLT 60 Query: 59 RDAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWY 118 RD+ S+SMGLVS+ATTAGWK PWQL A +WYTWVIA++GVDLL+Y Sbjct: 61 RDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYY 120 Query: 119 TYHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAA 178 +YHR+AHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF + Sbjct: 121 SYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCS 180 Query: 179 FSVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFG 238 +S+NLIYQFWVHTERI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG Sbjct: 181 WSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFG 240 Query: 239 TFQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 +FQ E+FRP YGLTK V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 SFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 298 >tr|A4KHW6|A4KHW6_MYCTU Tax_Id=395095 SubName: Full=Membrane-bound C-5 sterol desaturase erg3 (Sterol-c5-desaturase);[Mycobacterium tuberculosis str. Haarlem] Length = 314 Score = 426 bits (1094), Expect = e-117 Identities = 203/298 (68%), Positives = 230/298 (77%), Gaps = 2/298 (0%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHT 58 MD + LP MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ T Sbjct: 1 MDAVAGFFSALPEEMRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLT 60 Query: 59 RDAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWY 118 RD+ S+SMGLVS+ATTAGWK PWQL A +WYTWVIA++GVDLL+Y Sbjct: 61 RDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYY 120 Query: 119 TYHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAA 178 +YHR+AHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF + Sbjct: 121 SYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCS 180 Query: 179 FSVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFG 238 +S+NLIYQFWVHTERI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG Sbjct: 181 WSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFG 240 Query: 239 TFQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 +FQ E+FRP YGLTK V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 SFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 298 >tr|A2VIT4|A2VIT4_MYCTU Tax_Id=348776 SubName: Full=Membrane-bound C-5 sterol desaturase erg3 (Sterol-c5-desaturase);[Mycobacterium tuberculosis C] Length = 314 Score = 426 bits (1094), Expect = e-117 Identities = 203/298 (68%), Positives = 230/298 (77%), Gaps = 2/298 (0%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHT 58 MD + LP MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ T Sbjct: 1 MDAVAGFFSALPEEMRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLT 60 Query: 59 RDAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWY 118 RD+ S+SMGLVS+ATTAGWK PWQL A +WYTWVIA++GVDLL+Y Sbjct: 61 RDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYY 120 Query: 119 TYHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAA 178 +YHR+AHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF + Sbjct: 121 SYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCS 180 Query: 179 FSVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFG 238 +S+NLIYQFWVHTERI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG Sbjct: 181 WSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFG 240 Query: 239 TFQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 +FQ E+FRP YGLTK V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 SFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 298 >tr|D6G7J6|D6G7J6_MYCTU Tax_Id=478435 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis KZN 605] Length = 304 Score = 422 bits (1084), Expect = e-116 Identities = 200/288 (69%), Positives = 227/288 (78%), Gaps = 2/288 (0%) Query: 11 LPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMG 68 +P MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMG Sbjct: 1 MPEEMRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMG 60 Query: 69 LVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVR 128 LVS+ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVR Sbjct: 61 LVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVR 120 Query: 129 LIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFW 188 LIWATHQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFW Sbjct: 121 LIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFW 180 Query: 189 VHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPR 248 VHTERI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP Sbjct: 181 VHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPH 240 Query: 249 YGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 YGLTK V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 YGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 288 >sp|P68435|ERG3_MYCTU Tax_Id=1773 (erg3)RecName: Full=C-5 sterol desaturase; EC=1.3.-.-; AltName: Full=Sterol-C5-desaturase;[Mycobacterium tuberculosis] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >sp|P68434|ERG3_MYCBO Tax_Id=1765 (erg3)RecName: Full=C-5 sterol desaturase; EC=1.3.-.-; AltName: Full=Sterol-C5-desaturase;[Mycobacterium bovis] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|C1AP90|C1AP90_MYCBT Tax_Id=561275 (erg3)SubName: Full=Membrane-bound C-5 sterol desaturase;[Mycobacterium bovis] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|A5U3I1|A5U3I1_MYCTA Tax_Id=419947 (erg3)SubName: Full=Sterol desaturase-related protein;[Mycobacterium tuberculosis] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|A1KJM5|A1KJM5_MYCBP Tax_Id=410289 (erg3)SubName: Full=Membrane-bound C-5 Sterol desaturase erg3; EC=1.3.-.-;[Mycobacterium bovis] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|A0PSJ3|A0PSJ3_MYCUA Tax_Id=362242 (erg3)SubName: Full=Membrane-bound C-5 sterol desaturase Erg3;[Mycobacterium ulcerans] Length = 320 Score = 419 bits (1077), Expect = e-115 Identities = 197/301 (65%), Positives = 225/301 (74%), Gaps = 2/301 (0%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPA--EGDRAPAGAFHT 58 M L L LP MRDPV+FAIPFFL LLT+EW AAR+LE ++ E R +G++HT Sbjct: 1 MSALPGFLAVLPGEMRDPVLFAIPFFLFLLTVEWAAARKLEKLEAGATETPRPVSGSYHT 60 Query: 59 RDAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWY 118 RD+ ++SMGLVS+ T A WK PW L +WYTWVIA++GVDLL+Y Sbjct: 61 RDSVATISMGLVSLVTIAFWKTMALLGYAAIYTYVAPWHLSPGRWYTWVIAIVGVDLLYY 120 Query: 119 TYHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAA 178 TYHR+AHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGE++ W W+VF Sbjct: 121 TYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEVLMWVPLPLLGLPPWMVFFG 180 Query: 179 FSVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFG 238 FSV+LIYQFWVHTERI KLPR EF+FNTPSHHRVHHG D++YLD+NYGGILIIWDRLF Sbjct: 181 FSVSLIYQFWVHTERINKLPRWFEFIFNTPSHHRVHHGMDQMYLDKNYGGILIIWDRLFR 240 Query: 239 TFQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPAR 298 +FQ E RP YGLTKPV T+NIWKLQT EYVAIA D RSA R DRLGY FGPPGW P+ Sbjct: 241 SFQAETARPHYGLTKPVDTFNIWKLQTREYVAIARDWRSATRLRDRLGYAFGPPGWQPST 300 Query: 299 T 299 T Sbjct: 301 T 301 >tr|D6FUQ7|D6FUQ7_MYCTU Tax_Id=611304 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis K85] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|D6FB30|D6FB30_MYCTU Tax_Id=611303 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis CPHL_A] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|D6F4R2|D6F4R2_MYCTU Tax_Id=611302 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis T46] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|D5ZHY1|D5ZHY1_MYCTU Tax_Id=537210 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis T17] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|D5Z2X5|D5Z2X5_MYCTU Tax_Id=537209 SubName: Full=Membrane-bound C-5 sterol desaturase erg3 (Sterol-c5-desaturase);[Mycobacterium tuberculosis GM 1503] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|D5YFY0|D5YFY0_MYCTU Tax_Id=520140 SubName: Full=Membrane-bound c-5 sterol desaturase erg3;[Mycobacterium tuberculosis EAS054] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|D5Y4A9|D5Y4A9_MYCTU Tax_Id=520141 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis T85] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|D5XUB3|D5XUB3_MYCTU Tax_Id=515617 SubName: Full=Membrane-bound C-5 sterol desaturase erg3;[Mycobacterium tuberculosis T92] Length = 300 Score = 419 bits (1077), Expect = e-115 Identities = 199/284 (70%), Positives = 225/284 (79%), Gaps = 2/284 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPA-GAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIP FLLLL +EWTAAR+LE ++ A G PA GA+ TRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSI 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 ATTAGWK PWQL A +WYTWVIA++GVDLL+Y+YHR+AHRVRLIWA Sbjct: 61 ATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGEI+ W W+VF ++S+NLIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI +LPR EFVFNTPSHHRVHHG D +YLD+NYGGILIIWDRLFG+FQ E+FRP YGLT Sbjct: 181 RIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 K V T+NIWKLQT EYVAI D RSA R DRLGYVFGPPGW P Sbjct: 241 KRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEP 284 >tr|B2HSW0|B2HSW0_MYCMM Tax_Id=216594 (erg3)SubName: Full=Membrane-bound C-5 sterol desaturase Erg3;[Mycobacterium marinum] Length = 302 Score = 414 bits (1063), Expect = e-113 Identities = 193/287 (67%), Positives = 219/287 (76%), Gaps = 2/287 (0%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPA--EGDRAPAGAFHTRDAWTSVSMGLVSV 72 MRDPV+FAIPFFL LLT+EW AAR+LE ++ E R +G++HTRD+ S+SMGLVS+ Sbjct: 1 MRDPVLFAIPFFLFLLTVEWAAARKLEKLEAGATETPRPASGSYHTRDSVASISMGLVSL 60 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 T A WK PW L +WYTWVIA++GVDLL+YTYHR+AHRVRLIWA Sbjct: 61 VTIAFWKTLALLGYAAIYTYVAPWHLSPGRWYTWVIAIVGVDLLYYTYHRIAHRVRLIWA 120 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 THQAHHSSEYFNFATALRQKWNNSGE++ W W+VF FSV+LIYQFWVHTE Sbjct: 121 THQAHHSSEYFNFATALRQKWNNSGEVLMWVPLPLLGLPPWMVFFGFSVSLIYQFWVHTE 180 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 RI KLPR EF+FNTPSHHRVHHG D +YLD+NYGGILIIWDRLF +FQ E RP YGLT Sbjct: 181 RINKLPRWFEFIFNTPSHHRVHHGMDHMYLDKNYGGILIIWDRLFRSFQAETARPHYGLT 240 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPART 299 KPV T+NIWKLQT EYVAIA D RSA R DRLGY FGPPGW P+ T Sbjct: 241 KPVDTFNIWKLQTREYVAIARDWRSATRLRDRLGYAFGPPGWQPSTT 287 >tr|D5PKQ2|D5PKQ2_COREQ Tax_Id=525370 SubName: Full=C-5 sterol desaturase; EC=1.3.-.-;[Rhodococcus equi ATCC 33707] Length = 320 Score = 405 bits (1042), Expect = e-111 Identities = 187/297 (62%), Positives = 222/297 (74%), Gaps = 1/297 (0%) Query: 2 DTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGA-FHTRD 60 +TL + L P+ DPV AIP F++ L +EW AAR+LE + +G P A + RD Sbjct: 3 ETLTTAWGSLLEPLGDPVTLAIPAFVVFLGLEWFAARKLEETEIRDGRAYPPTAGYEFRD 62 Query: 61 AWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTY 120 A S+ MGLVS+ATTA WK PW LPA+ WYTWV+ L+G+DLL+YTY Sbjct: 63 ARASILMGLVSIATTAFWKFLALIGYSAIWVYLAPWHLPANAWYTWVLLLVGIDLLYYTY 122 Query: 121 HRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFS 180 HR+AHR+RLIWATHQAHHSSEYFNFATALRQKWNNSGEI+ W W++F FS Sbjct: 123 HRMAHRIRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWIPLPLIGIPPWMIFVGFS 182 Query: 181 VNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTF 240 V+L+YQF+VHTER+ +LPRPIE+VFNTPSHHRVHHG D YLDRNYGGILI+WDR+FGTF Sbjct: 183 VSLVYQFFVHTERVDRLPRPIEYVFNTPSHHRVHHGCDPEYLDRNYGGILIVWDRMFGTF 242 Query: 241 QEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPA 297 + E RP YGLTKPVGTY+IWKLQTHEY AI DVR+A+ W DRLGYVFGPPGW P+ Sbjct: 243 RAEQQRPTYGLTKPVGTYDIWKLQTHEYAAIGRDVRAAQSWRDRLGYVFGPPGWAPS 299 >tr|C1B9I3|C1B9I3_RHOOB Tax_Id=632772 SubName: Full=Hypothetical membrane protein;[Rhodococcus opacus] Length = 322 Score = 402 bits (1032), Expect = e-110 Identities = 188/293 (64%), Positives = 209/293 (71%), Gaps = 2/293 (0%) Query: 14 PMRDPVMFAIPFFLLLLTIEWTAARRLEHV--DPAEGDRAPAGAFHTRDAWTSVSMGLVS 71 P+ +PV AIP F+L L IEW AAR LE DP R G + RDA SV+MG VS Sbjct: 16 PLHEPVTLAIPAFVLFLAIEWFAARHLEDAATDPDGRSRPVRGGYERRDARASVAMGAVS 75 Query: 72 VATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIW 131 + TT WK PW LPAD WYTWVI +LGVD+L+Y YHR++HR+RLIW Sbjct: 76 ILTTTFWKLLALIGYSAIWVYLAPWHLPADAWYTWVILILGVDVLFYAYHRMSHRIRLIW 135 Query: 132 ATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHT 191 ATHQAHHSSEYFNF+TALRQKWNNS EI W W+VF FSVNL+YQF+VHT Sbjct: 136 ATHQAHHSSEYFNFSTALRQKWNNSAEIFMWIPLPLIGIPPWMVFIGFSVNLVYQFFVHT 195 Query: 192 ERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGL 251 ERI KLPRP+EFVFNTPSHHRVHHG D YLDRNY GILI+WDR+FGTFQ E RP YGL Sbjct: 196 ERIDKLPRPVEFVFNTPSHHRVHHGCDPEYLDRNYAGILIVWDRMFGTFQPETHRPTYGL 255 Query: 252 TKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTCETTE 304 TKPVGTYNIW LQTHEY AI D R A W DRLGYVFGPPGWTP+ T E + Sbjct: 256 TKPVGTYNIWTLQTHEYAAIGRDWRRASSWRDRLGYVFGPPGWTPSGTREADQ 308 >tr|C0ZM67|C0ZM67_RHOE4 Tax_Id=234621 SubName: Full=Conserved hypothetical membrane protein;[Rhodococcus erythropolis] Length = 313 Score = 393 bits (1010), Expect = e-107 Identities = 187/307 (60%), Positives = 217/307 (70%), Gaps = 2/307 (0%) Query: 2 DTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLE-HVDPAEGDRAPA-GAFHTR 59 +TL + L P+ DPV AIP F++ L IEW AAR LE H D A+G PA G + + Sbjct: 3 ETLLESWKSLLEPLHDPVTLAIPAFVIFLAIEWFAARALEDHPDDADGRARPAEGGYRSV 62 Query: 60 DAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYT 119 DA TSV +GLVS+AT+ WK PW L WYTWVI LLG+D+L+Y Sbjct: 63 DARTSVLLGLVSIATSTFWKVLALIGYSAIWVYLAPWHLSPTAWYTWVILLLGIDVLYYA 122 Query: 120 YHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAF 179 YHR+AHRVR+IWATHQAHHSSEYFNF+TALRQKWNNSGEI+ W W+VF F Sbjct: 123 YHRIAHRVRVIWATHQAHHSSEYFNFSTALRQKWNNSGEIIMWLPLPFLGIPPWMVFVGF 182 Query: 180 SVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGT 239 SV+L+YQF+VHTER+GKL RPIEF+FNTPSHHRVHHGSD YLDRNY GILIIWDR+FGT Sbjct: 183 SVSLVYQFFVHTERVGKLWRPIEFIFNTPSHHRVHHGSDAEYLDRNYAGILIIWDRMFGT 242 Query: 240 FQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPART 299 F E RP YGLT PVGTYNIWKLQT EY AIA D ++++ W R GYVFGPPGW P Sbjct: 243 FAAETHRPTYGLTTPVGTYNIWKLQTREYAAIARDWKASKSWRQRAGYVFGPPGWAPKAE 302 Query: 300 CETTEVT 306 + E T Sbjct: 303 VTSAEST 309 >tr|C3JQ25|C3JQ25_RHOER Tax_Id=596309 SubName: Full=C-5 sterol desaturase; EC=1.3.-.-;[Rhodococcus erythropolis SK121] Length = 313 Score = 392 bits (1007), Expect = e-107 Identities = 187/307 (60%), Positives = 216/307 (70%), Gaps = 2/307 (0%) Query: 2 DTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLE-HVDPAEGDRAPA-GAFHTR 59 +TL + L P+ DPV AIP F++ L IEW AAR LE H D A+G PA G + + Sbjct: 3 ETLLESWKSLLEPLHDPVTLAIPAFVIFLAIEWFAARALEDHPDDADGRARPAQGGYRSV 62 Query: 60 DAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYT 119 DA TSV +GLVS+AT+ WK PW L WYTWVI LLG+D+L+Y Sbjct: 63 DARTSVLLGLVSIATSTFWKVLALIGYSAIWVYLAPWHLSPTAWYTWVILLLGIDVLYYA 122 Query: 120 YHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAF 179 YHR+AHRVR+IWATHQAHHSSEYFNF+TALRQKWNNSGEI+ W W+VF F Sbjct: 123 YHRIAHRVRVIWATHQAHHSSEYFNFSTALRQKWNNSGEIIMWLPLPFLGIPPWMVFVGF 182 Query: 180 SVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGT 239 SV+L+YQF+VHTER+GKL RPIEF+FNTPSHHRVHHGSD YLDRNY GILIIWDR+FGT Sbjct: 183 SVSLVYQFFVHTERVGKLWRPIEFIFNTPSHHRVHHGSDAEYLDRNYAGILIIWDRMFGT 242 Query: 240 FQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPART 299 F E RP YGLT PVGTYNIWKLQT EY AIA D +++ W R GYVFGPPGW P Sbjct: 243 FAAETHRPTYGLTTPVGTYNIWKLQTREYAAIARDWKASTSWRQRAGYVFGPPGWAPKAE 302 Query: 300 CETTEVT 306 + E T Sbjct: 303 VTSAEST 309 >tr|D0L9B3|D0L9B3_GORB4 Tax_Id=526226 SubName: Full=Fatty acid hydroxylase;[Gordonia bronchialis] Length = 323 Score = 386 bits (992), Expect = e-105 Identities = 178/295 (60%), Positives = 219/295 (74%), Gaps = 6/295 (2%) Query: 7 VLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVD---PAEGD---RAPAGAFHTRD 60 +L+FLP MR+P + AIPFF+++LT+EW AA +LEH + P++ + + G ++ RD Sbjct: 1 MLDFLPEAMREPTVLAIPFFVVMLTLEWLAAWKLEHTETERPSQREVRASSEPGTYNWRD 60 Query: 61 AWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTY 120 + S+SMGLVS+AT+AGWK PW LPA W+TW+IA + +D L+Y Sbjct: 61 SRASLSMGLVSIATSAGWKLLGLLAYTALFAYVAPWHLPAGAWWTWLIAFVALDFLFYWE 120 Query: 121 HRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFS 180 HR+AHRVRL+WATHQAHHSSEYFNF TALRQKWNNS +V W VVFA +S Sbjct: 121 HRLAHRVRLVWATHQAHHSSEYFNFTTALRQKWNNSAGLVMWLPLPLLGVPPAVVFAVYS 180 Query: 181 VNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTF 240 NL+YQFW+HTER+GKL PIEFVFNTPSHHRVHHGSD YLDRNYGG I+WDR+FGTF Sbjct: 181 ANLVYQFWIHTERVGKLWAPIEFVFNTPSHHRVHHGSDTEYLDRNYGGTFIVWDRMFGTF 240 Query: 241 QEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWT 295 E RP YGLTKPV TYNIW+LQTHEYVAIA DVR+AR + +R+GY+FGPPGW+ Sbjct: 241 TAEAKRPTYGLTKPVDTYNIWRLQTHEYVAIARDVRAARGFRNRMGYLFGPPGWS 295 >tr|B2HF71|B2HF71_MYCMM Tax_Id=216594 (erg3_1)SubName: Full=Membrane-bound C-5 sterol desaturase Erg3_1;[Mycobacterium marinum] Length = 313 Score = 363 bits (933), Expect = 1e-98 Identities = 173/298 (58%), Positives = 206/298 (69%), Gaps = 2/298 (0%) Query: 1 MDTLRSVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRL--EHVDPAEGDRAPAGAFHT 58 M T SV + LP ++DPV+ PF +LL+ +EW AAR+L A+ R GA Sbjct: 1 MTTAMSVFDALPARLQDPVVLTAPFLILLIVLEWIAARKLLTTSAPAADDSRNAPGAHFG 60 Query: 59 RDAWTSVSMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWY 118 D S+S GLVS+ T A WK PW L +WYTWVIA+LG+DL++ Sbjct: 61 PDTIASLSTGLVSLVTGATWKTIAAIGYAAIYTYVAPWHLSPHQWYTWVIAVLGLDLIYC 120 Query: 119 TYHRVAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAA 178 HR+AHRVRLIWA HQ HHSSEYFN ATA+R +WN SGEI+ + WVVF + Sbjct: 121 VDHRIAHRVRLIWAAHQPHHSSEYFNLATAVRVEWNKSGEIIMFAILPLLGVPPWVVFFS 180 Query: 179 FSVNLIYQFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFG 238 +S+NL YQFWVHTERIGKLPR E++FNTPSHHRVHHG D++YLD+N+GGILIIWDR+ G Sbjct: 181 WSINLTYQFWVHTERIGKLPRWYEYLFNTPSHHRVHHGMDQMYLDKNFGGILIIWDRMLG 240 Query: 239 TFQEEVFRPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 TFQ E FRP YGLTKPV T+NIWKLQT+EY AI D RSA R DRLGYVFGPPGW P Sbjct: 241 TFQAEEFRPHYGLTKPVHTFNIWKLQTNEYAAIVRDWRSATRLRDRLGYVFGPPGWKP 298 >tr|Q0S934|Q0S934_RHOSR Tax_Id=101510 SubName: Full=Probable C-5 sterol desaturase;[Rhodococcus sp.] Length = 252 Score = 342 bits (877), Expect = 4e-92 Identities = 157/238 (65%), Positives = 174/238 (73%) Query: 67 MGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHR 126 MG VS+ TT WK PW LPAD WYTWVI +LGVD L+Y YHR+AHR Sbjct: 1 MGAVSILTTTFWKLLALIGYSAIWVYVAPWHLPADAWYTWVILILGVDALFYAYHRMAHR 60 Query: 127 VRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQ 186 +RLIWATHQAHHSSEYFNF+TALRQKWNNS EI+ W W+VF FSVNL+YQ Sbjct: 61 IRLIWATHQAHHSSEYFNFSTALRQKWNNSAEILMWIPLPLIGIPPWMVFIGFSVNLVYQ 120 Query: 187 FWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFR 246 F+VHTERI KL RP+EFVFNTPSHHRVHHG D YLDRNY GILI+WDR+FGTFQ E R Sbjct: 121 FFVHTERIDKLARPVEFVFNTPSHHRVHHGCDPEYLDRNYAGILIVWDRMFGTFQPETHR 180 Query: 247 PRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTCETTE 304 P YGLT PVGTY+IWKLQT EY AI D R A D+LGYVFGPPGW P+ T E + Sbjct: 181 PTYGLTTPVGTYSIWKLQTREYGAIVRDWRRASSSRDKLGYVFGPPGWAPSGTREADQ 238 >tr|D6B816|D6B816_9ACTO Tax_Id=457425 SubName: Full=C-5 sterol desaturase;[Streptomyces albus J1074] Length = 306 Score = 320 bits (821), Expect = 1e-85 Identities = 153/284 (53%), Positives = 184/284 (64%), Gaps = 5/284 (1%) Query: 18 PVMFAIPFFLLLLTIEWTAARRLEHVDPAE-GDRAPAGAFHTRDAW----TSVSMGLVSV 72 P+++A PFF L IE + L+ + E G P G +W T++ MG+ S+ Sbjct: 5 PLLYATPFFALFAGIELASFALLDRAERREPGAERPPGDRPKGHSWPDSRTNLVMGMGSL 64 Query: 73 ATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWA 132 +TA K PW LP D W++WV+ L+ VDL WYT HR +HRVR+ WA Sbjct: 65 VSTAVLKAATLVLFVYLYAALAPWHLPTDTWWSWVLLLIAVDLAWYTNHRFSHRVRIGWA 124 Query: 133 THQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTE 192 HQAHHSSEYFN TA+RQKWN E + W W ++ AFS NL+YQF+ HTE Sbjct: 125 GHQAHHSSEYFNLTTAVRQKWNPWSEAIFWAPLPLLGFAPWTIYVAFSFNLVYQFFTHTE 184 Query: 193 RIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLT 252 +GKLPRP+EFV NTPSHHRVHH SD YLD+NYGGILI+WDRLFGTFQEE RP YGLT Sbjct: 185 AVGKLPRPVEFVLNTPSHHRVHHASDPEYLDKNYGGILIVWDRLFGTFQEETHRPTYGLT 244 Query: 253 KPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 KPV TYN++ LQ HEY I DVRSA R D+LGYVF PPGW P Sbjct: 245 KPVNTYNVFTLQYHEYGNILADVRSAPRLRDKLGYVFRPPGWKP 288 >tr|A3TFN1|A3TFN1_9MICO Tax_Id=313589 SubName: Full=Putative uncharacterized protein;[Janibacter sp. HTCC2649] Length = 305 Score = 306 bits (784), Expect = 2e-81 Identities = 147/291 (50%), Positives = 185/291 (63%), Gaps = 2/291 (0%) Query: 6 SVLEFLPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDAWTSV 65 S LE + P DPV FAIPFF L + +E A + L+ D G+ P + + D +++ Sbjct: 3 SPLEIISNPFHDPVTFAIPFFALFIVLELLALKYLDDHDDELGEN-PKKGYSSPDTASNL 61 Query: 66 SMGLVSVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAH 125 + SV G + PW + A +TWV LL VDLLWY+YHR +H Sbjct: 62 GSAVGSVIINLGARFAALFLYFALWNIA-PWHMDASNPWTWVFTLLAVDLLWYSYHRASH 120 Query: 126 RVRLIWATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIY 185 R+R++WA HQAHHSS YFN++ ALRQKWN GE++ W W++F AFS+NLIY Sbjct: 121 RIRILWAAHQAHHSSVYFNYSVALRQKWNPWGELLFWTPLPLLGVPPWMIFFAFSLNLIY 180 Query: 186 QFWVHTERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVF 245 QFWVHTE I KL P EF+FNTPSHHRVHH S + YLD+NY GILIIWDR+FGT+ EE Sbjct: 181 QFWVHTETIPKLWGPFEFIFNTPSHHRVHHASQKQYLDKNYAGILIIWDRIFGTYAEEED 240 Query: 246 RPRYGLTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 P YGLT PV T+N ++LQ E++A DVR AR W DR GY+F PPGW P Sbjct: 241 IPVYGLTVPVTTHNPFRLQYGEFLAAVRDVRGARSWRDRAGYLFAPPGWKP 291 >tr|D4SHA0|D4SHA0_9ACTO Tax_Id=585531 SubName: Full=C-5 sterol desaturase; EC=1.3.-.-;[Aeromicrobium marinum DSM 15272] Length = 289 Score = 303 bits (777), Expect = 1e-80 Identities = 148/283 (52%), Positives = 180/283 (63%), Gaps = 7/283 (2%) Query: 14 PMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDAWTSVSMGLVSVA 73 P+++PV +A PFFLL + IE A + L+H D G + +DA TS+SMG+ SV Sbjct: 7 PLKNPVTWAAPFFLLTILIELAALKWLDHDDNVTG-------YALKDARTSISMGIGSVF 59 Query: 74 TTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWAT 133 +K W+LP D W+ WV+ LG+DL +Y +HR +HRVR+ WA Sbjct: 60 FLTVFKVLSFFGFVAVFSYLALWELPTDTWWYWVVLFLGLDLGYYFHHRFSHRVRIGWAG 119 Query: 134 HQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTER 193 HQAHHSSEY NF TALRQKWN E W W ++ AF NLIYQF+VHTE Sbjct: 120 HQAHHSSEYMNFGTALRQKWNPWFEFFFWLPLPLLGFAPWTLYVAFGFNLIYQFFVHTEL 179 Query: 194 IGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLTK 253 + +LPRP+E V NTPSHHRVHHGSD YLD+NY GI IIWDR+FGTF E RP YGLT Sbjct: 180 VDRLPRPVELVMNTPSHHRVHHGSDPEYLDKNYAGIFIIWDRIFGTFAAEKQRPTYGLTY 239 Query: 254 PVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTP 296 V TYN+ +LQ EYV IA DVR A+ +LGYVFGPPGW P Sbjct: 240 KVDTYNLMRLQYGEYVRIARDVRGAKSLRTKLGYVFGPPGWQP 282 >tr|D3CKC9|D3CKC9_9ACTO Tax_Id=648999 SubName: Full=Fatty acid hydroxylase;[Micromonospora sp. L5] Length = 275 Score = 276 bits (705), Expect = 3e-72 Identities = 139/280 (49%), Positives = 174/280 (62%), Gaps = 9/280 (3%) Query: 19 VMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDAWTSVSMGLVSVATTAGW 78 V++A+P FLLL+ IE + R L P + +R + RD TS+SMGL S W Sbjct: 5 VLYAVPAFLLLIVIEAVSYRFL----PDDDERG----YELRDTTTSLSMGLGSQIIGFPW 56 Query: 79 KXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWATHQAHH 138 K P D W+TWVI DL +Y +HR H VR++WA+H HH Sbjct: 57 KLLTVGLFAALWTVAPVHLSPGD-WWTWVILFFADDLAYYWFHRSHHEVRVLWASHVVHH 115 Query: 139 SSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTERIGKLP 198 SS Y+NF+TALRQ W + W W++F SV+L+YQF++HTERI LP Sbjct: 116 SSVYYNFSTALRQSWTPMTSLPFWLPLALLGIPPWMIFLQQSVSLLYQFFLHTERINVLP 175 Query: 199 RPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLTKPVGTY 258 RPIE++FNTPSHHRVHHGS+ YLDRNYGGILI+WDRLFG+F+ E RYGLTK +GTY Sbjct: 176 RPIEWIFNTPSHHRVHHGSNTEYLDRNYGGILIVWDRLFGSFEPERATARYGLTKNIGTY 235 Query: 259 NIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPAR 298 N ++ THE+ AI DVR A W RLGY+FG PGW PAR Sbjct: 236 NPLRVATHEFAAIWSDVRRADSWRHRLGYLFGRPGWQPAR 275 >tr|D1S248|D1S248_9ACTO Tax_Id=644283 SubName: Full=Fatty acid hydroxylase;[Micromonospora aurantiaca ATCC 27029] Length = 275 Score = 275 bits (703), Expect = 5e-72 Identities = 139/280 (49%), Positives = 174/280 (62%), Gaps = 9/280 (3%) Query: 19 VMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDAWTSVSMGLVSVATTAGW 78 V++A+P FLLL+ IE + R L P + +R + RD TS+SMGL S W Sbjct: 5 VLYAVPAFLLLIVIEAVSYRFL----PDDDERG----YELRDTTTSLSMGLGSQIIGFPW 56 Query: 79 KXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWATHQAHH 138 K P D W+TWVI DL +Y +HR H VR++WA+H HH Sbjct: 57 KLLTVGLFAALWTVAPVHLSPGD-WWTWVILFFADDLAYYWFHRSHHEVRVLWASHVVHH 115 Query: 139 SSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTERIGKLP 198 SS Y+NF+TALRQ W + W W++F SV+L+YQF++HTERI LP Sbjct: 116 SSVYYNFSTALRQSWTPMTSLPFWLPLALLGIPPWMIFLQQSVSLLYQFFLHTERINVLP 175 Query: 199 RPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLTKPVGTY 258 RPIE++FNTPSHHRVHHGS+ YLDRNYGGILI+WDRLFG+F+ E RYGLTK +GTY Sbjct: 176 RPIEWIFNTPSHHRVHHGSNIEYLDRNYGGILIVWDRLFGSFEPERATARYGLTKNIGTY 235 Query: 259 NIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPAR 298 N ++ THE+ AI DVR A W RLGY+FG PGW PAR Sbjct: 236 NPLRVATHEFAAIWSDVRRADSWRHRLGYLFGRPGWQPAR 275 >tr|Q5YZB6|Q5YZB6_NOCFA Tax_Id=37329 SubName: Full=Putative uncharacterized protein;[Nocardia farcinica] Length = 274 Score = 261 bits (668), Expect = 6e-68 Identities = 133/283 (46%), Positives = 171/283 (60%), Gaps = 10/283 (3%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDAWTSVSMGLVSVAT 74 M D + AIP F++ L +E + L D +H RD TS+ MGL +V Sbjct: 1 MFDLIAHAIPVFVVCLVLEAVSFHLLPDDDEL--------GYHARDTVTSLLMGLGNVVI 52 Query: 75 TAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIWATH 134 GWK P LP D TWV+ D ++Y YHR H VRL WA+H Sbjct: 53 NIGWKLVVVAVYAAVYLAS-PLHLPTDHPLTWVLLFFADDFVYYWYHRTHHTVRLFWASH 111 Query: 135 QAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHTERI 194 AHHSS +FN +TALRQ W + W W+V S++L+YQF++HTER+ Sbjct: 112 VAHHSSRFFNLSTALRQTWTPFTALPYWLPLALVFPP-WMVLLQQSISLLYQFFIHTERV 170 Query: 195 GKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGLTKP 254 G L RPIE+VF+TPSHHRVHHG++++YLDRNYGGILI+WDRLFGTF+ E R RYGLTK Sbjct: 171 GTLWRPIEWVFDTPSHHRVHHGANDVYLDRNYGGILIVWDRLFGTFEPEGERVRYGLTKN 230 Query: 255 VGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPA 297 + T+N ++ THE+VAI DVR+AR W R G++F PGW PA Sbjct: 231 IDTFNPVRVATHEFVAIWRDVRAARDWRTRFGHLFRGPGWAPA 273 >tr|D3F644|D3F644_CONWI Tax_Id=469383 SubName: Full=Fatty acid hydroxylase;[Conexibacter woesei] Length = 314 Score = 259 bits (662), Expect = 3e-67 Identities = 132/293 (45%), Positives = 167/293 (56%), Gaps = 4/293 (1%) Query: 15 MRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGA---FHTRDAWTSVSMGLVS 71 M + + AIPFFLL + +E D A G G + RD TS++MG Sbjct: 1 MLEVFLAAIPFFLLSIALEAFVLAHHAREDRAGGAGGGGGGMLGYERRDTRTSLAMGAGH 60 Query: 72 VATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLIW 131 + WK P ++P D W+ WV+ D+ +Y +HR HR+RL W Sbjct: 61 LVVLGAWKIVVLAVFAALYSLS-PLRVPTDAWWGWVLLFFADDVAFYLHHRAHHRIRLFW 119 Query: 132 ATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVHT 191 A H HHSSE +N +TALRQ W + W W +F A S +L+ QF +HT Sbjct: 120 AQHVVHHSSERYNLSTALRQDWTPFSTGIFWLWMPLAGFAPWTIFLAQSWSLLCQFGLHT 179 Query: 192 ERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYGL 251 E I LPRPIE++FNTPSHHRVHHGS + YLDRNYGGILI+WDRLFGTF+ E R RYGL Sbjct: 180 ETIRTLPRPIEWIFNTPSHHRVHHGSQQQYLDRNYGGILIVWDRLFGTFEPERERVRYGL 239 Query: 252 TKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPARTCETTE 304 T+ + T+N ++ HEY AI HDVR+A W RLGY F PGW PA +TE Sbjct: 240 TRNIDTFNPVRVAFHEYAAIWHDVRTATSWRARLGYAFRGPGWRPASRELSTE 292 >tr|D1WX07|D1WX07_9ACTO Tax_Id=649189 SubName: Full=Fatty acid hydroxylase;[Streptomyces sp. ACT-1] Length = 322 Score = 254 bits (650), Expect = 7e-66 Identities = 136/287 (47%), Positives = 172/287 (59%), Gaps = 10/287 (3%) Query: 11 LPPPMRDPVMFAIPFFLLLLTIEWTAARRLEHVDPAEGDRAPAGAFHTRDAWTSVSMGLV 70 + P + D V+++IP F+LL IE + R + P E A + TRDA TS++MGL Sbjct: 1 MEPNLPDVVLWSIPAFVLLTVIEMVSYR----LHPDED----AAGYETRDAATSLTMGLG 52 Query: 71 SVATTAGWKXXXXXXXXXXXXXXXPWQLPADKWYTWVIALLGVDLLWYTYHRVAHRVRLI 130 S+ WK P ++P W+T ++ LL D +Y HR H +R++ Sbjct: 53 SLGFDLLWKIPILAIYMGVYELT-PLRVPV-VWWTVLLMLLAQDFFYYWSHRGHHVIRIL 110 Query: 131 WATHQAHHSSEYFNFATALRQKWNNSGEIVAWXXXXXXXXXXWVVFAAFSVNLIYQFWVH 190 WA H HHSSE FN TALRQ W ++ + + S NL+YQFWVH Sbjct: 111 WACHVVHHSSEKFNLTTALRQPWTSATVWPFYLPLIACGVHPAALAFCQSANLVYQFWVH 170 Query: 191 TERIGKLPRPIEFVFNTPSHHRVHHGSDELYLDRNYGGILIIWDRLFGTFQEEVFRPRYG 250 TER+GKLPRP E+V NTPSHHRVHH S YLDRNYGGILIIWDR+FG+F EV RP YG Sbjct: 171 TERVGKLPRPFEYVLNTPSHHRVHHASQGGYLDRNYGGILIIWDRMFGSFAAEVERPVYG 230 Query: 251 LTKPVGTYNIWKLQTHEYVAIAHDVRSARRWTDRLGYVFGPPGWTPA 297 LTK + TYN ++ THEY AIA DVR+A W++R G VF PGW PA Sbjct: 231 LTKNITTYNPLRVATHEYAAIARDVRAAGTWSERAGRVFRGPGWQPA 277 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.325 0.138 0.479 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 2,621,231,007 Number of extensions: 105531706 Number of successful extensions: 238687 Number of sequences better than 10.0: 1048 Number of HSP's gapped: 237797 Number of HSP's successfully gapped: 1163 Length of query: 307 Length of database: 4,236,830,644 Length adjustment: 137 Effective length of query: 170 Effective length of database: 2,523,253,276 Effective search space: 428953056920 Effective search space used: 428953056920 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 80 (35.4 bits)