BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_3878
         (394 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|A0QZ31|A0QZ31_MYCS2 Tax_Id=246196 (cobL)SubName: Full=Precorr...   763   0.0  
tr|A3PZH7|A3PZH7_MYCSJ Tax_Id=164757 SubName: Full=Precorrin-6Y ...   546   e-153
tr|A1TAM9|A1TAM9_MYCVP Tax_Id=350058 SubName: Full=Precorrin-6Y ...   539   e-151
tr|A1UFW7|A1UFW7_MYCSK Tax_Id=189918 SubName: Full=Precorrin-6Y ...   535   e-150
tr|C6DPZ4|C6DPZ4_MYCTK Tax_Id=478434 SubName: Full=Precorrin-6y ...   530   e-148
tr|A5WP50|A5WP50_MYCTF Tax_Id=336982 SubName: Full=Precorrin-6y ...   530   e-148
tr|D6G6S8|D6G6S8_MYCTU Tax_Id=478435 SubName: Full=Precorrin-6y ...   530   e-148
tr|D6F5K0|D6F5K0_MYCTU Tax_Id=611302 SubName: Full=Precorrin-6y ...   530   e-148
tr|D5ZIS7|D5ZIS7_MYCTU Tax_Id=537210 SubName: Full=Precorrin-6y ...   530   e-148
tr|D5Z4T6|D5Z4T6_MYCTU Tax_Id=537209 SubName: Full=Precorrin-6y ...   530   e-148
tr|D5YRN0|D5YRN0_MYCTU Tax_Id=515616 SubName: Full=Precorrin-6y ...   530   e-148
tr|D5YGQ4|D5YGQ4_MYCTU Tax_Id=520140 SubName: Full=Precorrin-6y ...   530   e-148
tr|D5Y4R3|D5Y4R3_MYCTU Tax_Id=520141 SubName: Full=Precorrin-6y ...   530   e-148
tr|D5XUI6|D5XUI6_MYCTU Tax_Id=515617 SubName: Full=Precorrin-6y ...   530   e-148
tr|A4KIK9|A4KIK9_MYCTU Tax_Id=395095 SubName: Full=Precorrin-6y ...   530   e-148
tr|A2VJH7|A2VJH7_MYCTU Tax_Id=348776 SubName: Full=Precorrin-6y ...   530   e-148
sp|Q10671|COBL_MYCTU Tax_Id=1773 (cobL)RecName: Full=Precorrin-6...   526   e-147
tr|A5U497|A5U497_MYCTA Tax_Id=419947 (cobL)SubName: Full=Precorr...   526   e-147
tr|Q73YY6|Q73YY6_MYCPA Tax_Id=1770 (cobL)SubName: Full=CobL;[Myc...   524   e-146
tr|A4TB36|A4TB36_MYCGI Tax_Id=350054 SubName: Full=Precorrin-6Y ...   522   e-146
tr|D5P4R0|D5P4R0_9MYCO Tax_Id=525368 (cobL)SubName: Full=Precorr...   516   e-144
tr|A0QFD2|A0QFD2_MYCA1 Tax_Id=243243 (cobL)SubName: Full=Precorr...   513   e-143
tr|B2HFS7|B2HFS7_MYCMM Tax_Id=216594 (cobL)SubName: Full=Precorr...   508   e-142
tr|A0PQQ6|A0PQQ6_MYCUA Tax_Id=362242 (cobL)SubName: Full=Precorr...   505   e-141
tr|Q1B943|Q1B943_MYCSS Tax_Id=164756 SubName: Full=Precorrin-6Y ...   480   e-133
tr|B1MAK5|B1MAK5_MYCA9 Tax_Id=561007 SubName: Full=Probable prec...   441   e-122
tr|Q7VER4|Q7VER4_MYCBO Tax_Id=1765 (cobLb)SubName: Full=Probable...   399   e-109
tr|C1APZ1|C1APZ1_MYCBT Tax_Id=561275 (cobLb)SubName: Full=Putati...   399   e-109
tr|A1KKB8|A1KKB8_MYCBP Tax_Id=410289 (cobLb)SubName: Full=Probab...   399   e-109
tr|D6FVV0|D6FVV0_MYCTU Tax_Id=611304 SubName: Full=Precorrin-6y ...   399   e-109
tr|D6FCL0|D6FCL0_MYCTU Tax_Id=611303 SubName: Full=Precorrin-6y ...   399   e-109
tr|C1ARY6|C1ARY6_RHOOB Tax_Id=632772 (cobL)SubName: Full=Precorr...   374   e-101
tr|D2AR10|D2AR10_STRRD Tax_Id=479432 SubName: Full=Precorrin-6Y ...   369   e-100
tr|Q5YUY8|Q5YUY8_NOCFA Tax_Id=37329 (cobL)SubName: Full=Putative...   365   6e-99
tr|D5PLJ9|D5PLJ9_COREQ Tax_Id=525370 (cobL)SubName: Full=Precorr...   362   4e-98
tr|Q0SIH5|Q0SIH5_RHOSR Tax_Id=101510 (cobL)SubName: Full=Precorr...   362   6e-98
tr|A4FM52|A4FM52_SACEN Tax_Id=405948 (cobL)SubName: Full=Precorr...   355   5e-96
tr|D3M4W5|D3M4W5_9ACTO Tax_Id=656024 SubName: Full=Precorrin-6y ...   354   1e-95
tr|D6AXX4|D6AXX4_9ACTO Tax_Id=457425 SubName: Full=Precorrin-6Y ...   352   4e-95
tr|D2Q4R1|D2Q4R1_KRIFD Tax_Id=479435 SubName: Full=Precorrin-6y ...   351   9e-95
tr|A8KXX2|A8KXX2_FRASN Tax_Id=298653 SubName: Full=Precorrin-6y ...   350   3e-94
tr|C3JTA2|C3JTA2_RHOER Tax_Id=596309 SubName: Full=Precorrin-6Y ...   348   6e-94
tr|C0ZZT3|C0ZZT3_RHOE4 Tax_Id=234621 (cobL)SubName: Full=Precorr...   347   1e-93
tr|B1VNX8|B1VNX8_STRGG Tax_Id=455632 SubName: Full=Putative meth...   342   5e-92
tr|C6WCV9|C6WCV9_ACTMD Tax_Id=446462 SubName: Full=Precorrin-6y ...   342   7e-92

>tr|A0QZ31|A0QZ31_MYCS2 Tax_Id=246196 (cobL)SubName:
           Full=Precorrin-6Y C5,15-methyltransferase
           (Decarboxylating); EC=2.1.1.132;[Mycobacterium
           smegmatis]
          Length = 394

 Score =  763 bits (1970), Expect = 0.0
 Identities = 381/394 (96%), Positives = 381/394 (96%)

Query: 1   MKLIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPAL 60
           MKLIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPAL
Sbjct: 1   MKLIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPAL 60

Query: 61  PTLFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDT 120
           PTLFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDT
Sbjct: 61  PTLFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDT 120

Query: 121 EVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERR 180
           EVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERR
Sbjct: 121 EVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERR 180

Query: 181 RDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAAL 240
           RDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAAL
Sbjct: 181 RDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAAL 240

Query: 241 GPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGA 300
           GPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGA
Sbjct: 241 GPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGA 300

Query: 301 APECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKG 360
           APECFD             VTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKG
Sbjct: 301 APECFDGAPAPAAIFIGGGVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKG 360

Query: 361 GDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVKA 394
           GDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVKA
Sbjct: 361 GDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVKA 394


>tr|A3PZH7|A3PZH7_MYCSJ Tax_Id=164757 SubName: Full=Precorrin-6Y
           C5,15-methyltransferase (Decarboxylating);
           EC=2.1.1.132;[Mycobacterium sp.]
          Length = 390

 Score =  546 bits (1407), Expect = e-153
 Identities = 269/389 (69%), Positives = 306/389 (78%)

Query: 5   IVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTLF 64
           +VVGIGADGM GL+ AS DEL RAT V+G+ RQL LLDDTV A+RREWPSP++PAL  + 
Sbjct: 1   MVVGIGADGMAGLARASADELRRATTVYGSRRQLDLLDDTVTAERREWPSPLMPALQAIR 60

Query: 65  DDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEVIS 124
           DD  GDVH+VASGDP+ HGIG + +R+FG DRV VLPHVSSVTLACAR+GW V DTEVIS
Sbjct: 61  DDPAGDVHIVASGDPMLHGIGGSAVRMFGPDRVTVLPHVSSVTLACARLGWAVQDTEVIS 120

Query: 125 LVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRDGT 184
           LVTA P TAVRRGG AVVLSRD STP  LAR LT++GRG+S  T+LEQLGGP ERRR GT
Sbjct: 121 LVTAAPRTAVRRGGHAVVLSRDESTPATLARSLTDTGRGESEMTLLEQLGGPEERRRTGT 180

Query: 185 AADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGPRP 244
           A  WSA P  DVD LNV+AV YRP+DR+   LPDE F+HDGQITKQS+RAVTLAAL PRP
Sbjct: 181 ARSWSADPPGDVDALNVIAVRYRPDDRQLQVLPDEAFAHDGQITKQSMRAVTLAALAPRP 240

Query: 245 GELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAPEC 304
           GELLWDVG+GSGSI IEWCRS  GC A+AFERD  RR+RI AN +A GV V++RGAAPE 
Sbjct: 241 GELLWDVGAGSGSIGIEWCRSGAGCRAIAFERDGTRRERIAANADAHGVDVEVRGAAPES 300

Query: 305 FDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGDLR 364
           FD             +T PG+L+ C D L  GGRLV NAVT ESE V+ QWYS+ GG+LR
Sbjct: 301 FDGVPQPSAVFIGGGLTRPGLLDGCVDALPPGGRLVANAVTAESEVVLVQWYSKMGGELR 360

Query: 365 RYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           RYQHY+G  VG FT WRPA+PVTQW VVK
Sbjct: 361 RYQHYRGEPVGTFTGWRPAMPVTQWVVVK 389


>tr|A1TAM9|A1TAM9_MYCVP Tax_Id=350058 SubName: Full=Precorrin-6Y
           C5,15-methyltransferase (Decarboxylating);
           EC=2.1.1.132;[Mycobacterium vanbaalenii]
          Length = 395

 Score =  539 bits (1389), Expect = e-151
 Identities = 270/391 (69%), Positives = 308/391 (78%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GL+ ASR ELARATVV+G+ RQL LLD TV A RR WP+P+LPAL T
Sbjct: 1   MIIVVGIGADGMAGLAPASRAELARATVVYGSRRQLELLDGTVTAPRRAWPTPLLPALGT 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L D    DVHVVASGDP+ HGIG+TLIRL G D+V VLPHVSSVTLACAR+GW+V DTE+
Sbjct: 61  LLDGGDADVHVVASGDPMLHGIGSTLIRLHGPDKVAVLPHVSSVTLACARVGWSVQDTEI 120

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLV   PHTAVRRGG+AVVLSRD STP +LARLLT++GRGDS  TVLEQLGGP E RR 
Sbjct: 121 ISLVWHEPHTAVRRGGQAVVLSRDGSTPAELARLLTDAGRGDSELTVLEQLGGPKELRRT 180

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
            TA +W+A P  DVDDLNV+AV Y P+ R    LPD+ F+HDGQ+TKQ IRA TLAAL P
Sbjct: 181 STAREWAARPPADVDDLNVMAVRYLPDVRVLGTLPDDAFAHDGQLTKQMIRAATLAALAP 240

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPGELLWDVG+GSGSI+IEWCRS PGC A+AFERDE RR RI  N  A G  V++R  AP
Sbjct: 241 RPGELLWDVGAGSGSISIEWCRSGPGCRAIAFERDEARRARITENAVAHGAGVEVRFDAP 300

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           E FD             V+ PG+++AC++RL  GGRLV NAVTVESEAV+AQWYS  GG+
Sbjct: 301 ESFDSSPPPAAVFVGGGVSRPGMIDACWERLGPGGRLVANAVTVESEAVLAQWYSRVGGE 360

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRRYQHY+G AVG FT WRPA+PVTQWSV K
Sbjct: 361 LRRYQHYRGEAVGSFTGWRPAMPVTQWSVTK 391


>tr|A1UFW7|A1UFW7_MYCSK Tax_Id=189918 SubName: Full=Precorrin-6Y
           C5,15-methyltransferase (Decarboxylating);
           EC=2.1.1.132;[Mycobacterium sp.]
          Length = 390

 Score =  535 bits (1378), Expect = e-150
 Identities = 265/389 (68%), Positives = 303/389 (77%)

Query: 5   IVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTLF 64
           +VVGIGADGM GL+ AS DEL RAT V+G+ RQL LLDDTV A+R EWPSP++PAL  + 
Sbjct: 1   MVVGIGADGMAGLARASADELRRATTVYGSRRQLDLLDDTVTAERHEWPSPLMPALQAIR 60

Query: 65  DDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEVIS 124
           DD  GDVH+VASGDP+ +GIG + +R+FG  RV VLPHVSSVTLACAR+GW V DTEVIS
Sbjct: 61  DDPAGDVHIVASGDPMLYGIGGSAVRIFGPGRVTVLPHVSSVTLACARLGWPVQDTEVIS 120

Query: 125 LVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRDGT 184
           LVTA P TAVRRGG AVVLSRD S+P  LARLLT++GRG+S  T+LEQLGGP ERRR GT
Sbjct: 121 LVTAAPRTAVRRGGHAVVLSRDESSPAALARLLTDTGRGESEMTLLEQLGGPEERRRTGT 180

Query: 185 AADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGPRP 244
           A  WSA P  DVD LNVVAV Y P+DR+   LPD  F+HDGQITKQS+RAVTLAAL PRP
Sbjct: 181 ARSWSADPPGDVDALNVVAVRYLPDDRQLQVLPDGAFAHDGQITKQSMRAVTLAALAPRP 240

Query: 245 GELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAPEC 304
           G LLWDVG+GSGSI IEWCRS PGC A+AFERDE RR+RI AN +A GV V++RGAAPE 
Sbjct: 241 GGLLWDVGAGSGSIGIEWCRSGPGCRAIAFERDETRRERIAANADAHGVDVEVRGAAPES 300

Query: 305 FDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGDLR 364
            D             +T PG+L+ C D L  GGRLV NAVT ESE V+ QWYS+ GG+LR
Sbjct: 301 LDGVPQPSAVFIGGGLTRPGLLDGCVDALPPGGRLVANAVTAESEVVLVQWYSKMGGELR 360

Query: 365 RYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           RYQHY+G  VG FT WRPA+PVTQW VVK
Sbjct: 361 RYQHYRGEPVGTFTGWRPAMPVTQWVVVK 389


>tr|C6DPZ4|C6DPZ4_MYCTK Tax_Id=478434 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|A5WP50|A5WP50_MYCTF Tax_Id=336982 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|D6G6S8|D6G6S8_MYCTU Tax_Id=478435 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis KZN
           605]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|D6F5K0|D6F5K0_MYCTU Tax_Id=611302 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis T46]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|D5ZIS7|D5ZIS7_MYCTU Tax_Id=537210 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis T17]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|D5Z4T6|D5Z4T6_MYCTU Tax_Id=537209 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis GM
           1503]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|D5YRN0|D5YRN0_MYCTU Tax_Id=515616 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis
           02_1987]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|D5YGQ4|D5YGQ4_MYCTU Tax_Id=520140 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis
           EAS054]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|D5Y4R3|D5Y4R3_MYCTU Tax_Id=520141 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis T85]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|D5XUI6|D5XUI6_MYCTU Tax_Id=515617 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis T92]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|A4KIK9|A4KIK9_MYCTU Tax_Id=395095 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis str.
           Haarlem]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|A2VJH7|A2VJH7_MYCTU Tax_Id=348776 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis C]
          Length = 390

 Score =  530 bits (1365), Expect = e-148
 Identities = 271/391 (69%), Positives = 304/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y P++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>sp|Q10671|COBL_MYCTU Tax_Id=1773 (cobL)RecName: Full=Precorrin-6Y
           C(5,15)-methyltransferase [decarboxylating];
           Short=Precorrin-6 methyltransferase; Short=Precorrin-6Y
           methylase; EC=2.1.1.132;[Mycobacterium tuberculosis]
          Length = 390

 Score =  526 bits (1355), Expect = e-147
 Identities = 270/391 (69%), Positives = 303/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y  ++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLLDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|A5U497|A5U497_MYCTA Tax_Id=419947 (cobL)SubName:
           Full=Precorrin-6y c5,15-methyltransferase;[Mycobacterium
           tuberculosis]
          Length = 390

 Score =  526 bits (1355), Expect = e-147
 Identities = 270/391 (69%), Positives = 303/391 (77%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GLS  SR EL RATV++G+ RQLALLDDTV A+R EWP+PMLPA+  
Sbjct: 1   MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG+TLIRLFG D V VLPHVS+VTLACARMGW V DTEV
Sbjct: 61  LSPD-GADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE GRGDS F+VLEQLGGP ERRRD
Sbjct: 120 ISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRD 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+  P  DVD+LNV+AV Y  ++R + A PDE F+HDGQITK  IR +TLAAL P
Sbjct: 180 GTARAWACDPPLDVDELNVIAVRYLLDERTSWA-PDEAFAHDGQITKHPIRVLTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+RR  I  N  AFGV VD+RG AP
Sbjct: 239 RPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             VT PG+LEAC D L  GG LV NAVTVESEA +A  YS  GG+
Sbjct: 299 DAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGE 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 359 LRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 389


>tr|Q73YY6|Q73YY6_MYCPA Tax_Id=1770 (cobL)SubName:
           Full=CobL;[Mycobacterium paratuberculosis]
          Length = 389

 Score =  524 bits (1349), Expect = e-146
 Identities = 263/391 (67%), Positives = 299/391 (76%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +I+VVGIGADGM GL+ ASR EL  A V++G+ RQL LLDDTV A RR+WPSPMLPAL +
Sbjct: 1   MIVVVGIGADGMAGLAEASRAELRSAAVIYGSKRQLDLLDDTVRAPRRQWPSPMLPALQS 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L DD  GDVH+VASGDPL HGIG TLIRL GA RVRVLPHVSSVTLACARMGW V DTEV
Sbjct: 61  LLDDHTGDVHIVASGDPLLHGIGGTLIRLHGAGRVRVLPHVSSVTLACARMGWNVHDTEV 120

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTAPPHTAVRRGG+A++LS+ A+TPT+LA LLT  GRGDS FTVLE+LG P E RRD
Sbjct: 121 ISLVTAPPHTAVRRGGQAIILSQGAATPTELAALLTAHGRGDSQFTVLERLGAPDEHRRD 180

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA DW+ A A D+D LNV+AV Y P D R   LPD+ F+HDGQITKQ IRAVTLAAL P
Sbjct: 181 GTARDWADA-AGDIDALNVIAVRYLP-DERVWPLPDDAFTHDGQITKQGIRAVTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPGE LWDVG+GSGSI++EWC    GC A AFERD QRR  + AN  AFG  +DLRG AP
Sbjct: 239 RPGERLWDVGAGSGSISVEWCLGGNGCRATAFERDAQRRRNLAANAAAFGAAIDLRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             +T PG+L+ACFD L +GGRLV N VT ESEAVV Q Y+  GG 
Sbjct: 299 DAFDDAEPPSAIFIGGGLTRPGLLDACFDHLPSGGRLVANVVTTESEAVVIQAYTRFGGQ 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G A+G FT W P  PVTQW+V +
Sbjct: 359 LRRFQHYHGKALGAFTGWHPQFPVTQWAVTR 389


>tr|A4TB36|A4TB36_MYCGI Tax_Id=350054 SubName: Full=Precorrin-6Y
           C5,15-methyltransferase (Decarboxylating);
           EC=2.1.1.132;[Mycobacterium gilvum]
          Length = 388

 Score =  522 bits (1345), Expect = e-146
 Identities = 255/381 (66%), Positives = 297/381 (77%)

Query: 14  MPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTLFDDFGGDVHV 73
           M GL   SR EL+RATV++G+ RQL LLD TV A RR WPSP+LPALP+L DD GGD+HV
Sbjct: 1   MSGLPEVSRSELSRATVIYGSQRQLDLLDGTVTAARRTWPSPLLPALPSLMDDSGGDIHV 60

Query: 74  VASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEVISLVTAPPHTA 133
           +ASGDPL HGIG TLI L GA RV VLPHVSSVTLACAR+GW V DTE+ISLV A PHTA
Sbjct: 61  IASGDPLLHGIGGTLITLLGAQRVAVLPHVSSVTLACARVGWPVQDTEIISLVNADPHTA 120

Query: 134 VRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRDGTAADWSAAPA 193
           VRRGG+AVVLSRD STP  LARLLT++GRGDS  T+LEQLGGPGE R   TA +W+A P 
Sbjct: 121 VRRGGQAVVLSRDGSTPAALARLLTDAGRGDSELTILEQLGGPGELRCSATAREWAARPP 180

Query: 194 PDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGPRPGELLWDVGS 253
            DVD LNV+AV Y P+ RR  ALPD+ F+HDGQITKQ+IRA TLAAL PRPG+LLWDVG+
Sbjct: 181 GDVDALNVIAVRYLPDARRHGALPDDAFAHDGQITKQAIRAATLAALAPRPGQLLWDVGA 240

Query: 254 GSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAPECFDXXXXXXX 313
           GSGS+++EWC +  GC AVAFERDE RR RI  N   FGVR+++   AP+ F        
Sbjct: 241 GSGSVSVEWCLAGTGCRAVAFERDEARRARITVNANTFGVRIEVGSDAPDSFGMAPPPDA 300

Query: 314 XXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGDLRRYQHYQGGA 373
                 V+ PG+L+AC+D L  GGR+VVNAVTVESEAV+A WYS+ GG+LRR+QHY+G A
Sbjct: 301 VFVGGGVSSPGLLQACWDALRDGGRMVVNAVTVESEAVLAHWYSQHGGELRRFQHYRGEA 360

Query: 374 VGGFTAWRPALPVTQWSVVKA 394
           VG FT WRPA+PVTQWSV KA
Sbjct: 361 VGTFTGWRPAMPVTQWSVTKA 381


>tr|D5P4R0|D5P4R0_9MYCO Tax_Id=525368 (cobL)SubName:
           Full=Precorrin-6y c5,15-methyltransferase;
           EC=2.1.1.132;[Mycobacterium parascrofulaceum ATCC
           BAA-614]
          Length = 389

 Score =  516 bits (1328), Expect = e-144
 Identities = 260/391 (66%), Positives = 300/391 (76%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +IIVVGIGADGM GL+A SRDEL RA+V++G+ RQL LLDDTV A RR+WPSPMLPAL T
Sbjct: 1   MIIVVGIGADGMAGLAATSRDELQRASVIYGSKRQLDLLDDTVAAPRRQWPSPMLPALQT 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L D    DVHVVASGDPL HGIG TLIRL+G D VRVLPHVSSVTLACARMGW   +TEV
Sbjct: 61  LRDRHTDDVHVVASGDPLLHGIGGTLIRLYGPDHVRVLPHVSSVTLACARMGWNAQETEV 120

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTAPPHTAVRRGG+A+VLS+   TP +LA LLT  GRGDS  T+LE LGGP E RRD
Sbjct: 121 ISLVTAPPHTAVRRGGQAIVLSKSRLTPHELAALLTAHGRGDSAMTILENLGGPTELRRD 180

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+ AP P+VDDLNV+A+ Y P+DR +  LPD+ F+HDGQITK  IRAVTLAAL P
Sbjct: 181 GTARQWAEAP-PNVDDLNVIALRYLPDDRLS-PLPDDAFAHDGQITKHGIRAVTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPGE LWDVG+GSGSI++EWC S  GCTAVAFERDE+RR  I  N  AFG  +D+R  AP
Sbjct: 239 RPGERLWDVGAGSGSISVEWCLSWAGCTAVAFERDERRRHNIGLNAAAFGADIDVRCDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
           + FD             +T PG+L+AC + L T GRLVVNAVT ESE+ +AQ +S  GG 
Sbjct: 299 DGFDGLDSPSAIFIGGGLTQPGLLDACLEHLPTRGRLVVNAVTAESESALAQSHSRLGGQ 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G  +GGFT WRP +PVTQW + K
Sbjct: 359 LRRFQHYHGEPLGGFTGWRPQMPVTQWVMTK 389


>tr|A0QFD2|A0QFD2_MYCA1 Tax_Id=243243 (cobL)SubName:
           Full=Precorrin-6Y C5,15-methyltransferase
           (Decarboxylating); EC=2.1.1.132;[Mycobacterium avium]
          Length = 389

 Score =  513 bits (1320), Expect = e-143
 Identities = 260/391 (66%), Positives = 294/391 (75%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +I+VVGIGADGM GL+ ASR EL  A V++G+ RQL LLDDTV A RR WPSPMLPAL +
Sbjct: 1   MIVVVGIGADGMAGLAEASRAELRSAAVIYGSKRQLDLLDDTVPAPRRHWPSPMLPALQS 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L DD  GDVH+VASGDPL HGIG TLIRL+GA RVRVLPHVSSVTLACARMGW V DTEV
Sbjct: 61  LLDDHTGDVHIVASGDPLLHGIGGTLIRLYGAGRVRVLPHVSSVTLACARMGWNVHDTEV 120

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVT  PHTAVRRGG+A+VLS+ A+TPT+LA LLT  GRGDS FTVLE+LG   E RRD
Sbjct: 121 ISLVTGQPHTAVRRGGQAIVLSQGAATPTELAALLTAHGRGDSQFTVLERLGALDEHRRD 180

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA DW A  A D+D LNV+AV Y P D R   LPD+ F+HDGQITKQ IRAVTLAAL P
Sbjct: 181 GTARDW-ADGAADIDPLNVIAVRYLP-DERVWPLPDDAFTHDGQITKQRIRAVTLAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPGE LWDVG+GSGSI++EWC S  GC A AFERD QRR  + AN  AFG  +D+RG AP
Sbjct: 239 RPGERLWDVGAGSGSISVEWCLSGTGCRATAFERDAQRRHNLAANAAAFGAAIDVRGDAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
             F              +T PG+L+ACFD L +GGRLV N VT ESEAVV Q Y+  GG 
Sbjct: 299 HAFVGAEPPSAIFIGGGLTRPGLLDACFDHLPSGGRLVANVVTTESEAVVIQAYTRFGGQ 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHY G A+G FT W P  PVTQW+V +
Sbjct: 359 LRRFQHYHGKALGAFTGWHPQFPVTQWAVTR 389


>tr|B2HFS7|B2HFS7_MYCMM Tax_Id=216594 (cobL)SubName:
           Full=Precorrin-6y methyltransferase, CobL;[Mycobacterium
           marinum]
          Length = 390

 Score =  508 bits (1307), Expect = e-142
 Identities = 254/391 (64%), Positives = 296/391 (75%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +I+VVGIGADGMPGLS ASR EL RAT+++G+ RQL LLD+TV   RREWPSPMLPAL  
Sbjct: 1   MIVVVGIGADGMPGLSDASRCELQRATIIYGSKRQLDLLDETVTTSRREWPSPMLPALRQ 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG TLIRLFG + VRV+PHVS+VTLACARMGW V DTEV
Sbjct: 61  LPAD-GPDIHVVASGDPLMHGIGGTLIRLFGPEHVRVVPHVSAVTLACARMGWNVHDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTAPPHTA+RRGG+A++LS   +TP+ LA LL   GRGDS F+VLEQLGG  ER R 
Sbjct: 120 ISLVTAPPHTALRRGGQAIILSNSKATPSQLAALLHAHGRGDSEFSVLEQLGGRAERHRH 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+A    DVDDLNV+A+ Y PE  R  A PD+ F+HDGQITK  IRA+T+AAL P
Sbjct: 180 GTARKWAAEAPVDVDDLNVIAIRYLPE-ARVLAPPDDAFAHDGQITKHGIRALTVAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPGE LWDVGSGSGSIA++WCRS PGCTAVAFERDE+RR  I +N  +FGV +D RG AP
Sbjct: 239 RPGERLWDVGSGSGSIAVQWCRSWPGCTAVAFERDERRRANIESNAVSFGVSIDARGEAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
             F+             +T PG+L++C   L TGGRLV N VT ESEA +   +S  GG 
Sbjct: 299 LAFEGTAEPSAIFLGGGLTQPGLLDSCLGHLPTGGRLVANVVTAESEAALVHAHSRLGGQ 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHYQG  +GGFT WRP +PVTQW+V K
Sbjct: 359 LRRFQHYQGEPLGGFTGWRPQMPVTQWAVTK 389


>tr|A0PQQ6|A0PQQ6_MYCUA Tax_Id=362242 (cobL)SubName:
           Full=Precorrin-6y methyltransferase, CobL;[Mycobacterium
           ulcerans]
          Length = 390

 Score =  505 bits (1301), Expect = e-141
 Identities = 254/391 (64%), Positives = 296/391 (75%), Gaps = 2/391 (0%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +I+VVGIGADG+PGLS ASR EL RAT+++G+ RQL LLD+TV A R EWPSPMLPAL  
Sbjct: 1   MIVVVGIGADGIPGLSDASRCELQRATIIYGSKRQLDLLDETVTASRPEWPSPMLPALQQ 60

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           L  D G D+HVVASGDPL HGIG TLIRLFG + VRV+PHVS+VTLACARMGW V DTEV
Sbjct: 61  LPAD-GPDIHVVASGDPLMHGIGGTLIRLFGPEHVRVVPHVSAVTLACARMGWNVHDTEV 119

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLVTAPPHTA+RRGG+A++LS   +TP+ LA LL   G GDS F+VLEQLGGP ER R 
Sbjct: 120 ISLVTAPPHTALRRGGQAIILSNSKATPSQLAALLHAHGSGDSEFSVLEQLGGPLERHRH 179

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQITKQSIRAVTLAALGP 242
           GTA  W+A    DVDDLNV+A+ Y PE  R  A PD+ F+HDGQITK  IRA+T+AAL P
Sbjct: 180 GTARKWAAEAPVDVDDLNVIAIRYLPE-ARVLAPPDDAFAHDGQITKHGIRALTVAALAP 238

Query: 243 RPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAP 302
           RPGE LWDVGSGSGSIA++WCRS PGCTAVAFERDE+RR  I +N  +FGV VD RG AP
Sbjct: 239 RPGERLWDVGSGSGSIAVQWCRSWPGCTAVAFERDERRRANIESNAVSFGVSVDARGEAP 298

Query: 303 ECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGD 362
             F+             +T PG+L++C   L TGGRLV N VT ESEA +   +S  GG 
Sbjct: 299 LAFEGTAEPSAIFLGGGLTQPGLLDSCLGHLPTGGRLVANVVTAESEAALVHAHSRLGGQ 358

Query: 363 LRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           LRR+QHYQG  +GGFT WRP +PVTQW+V K
Sbjct: 359 LRRFQHYQGEPLGGFTGWRPQMPVTQWAVTK 389


>tr|Q1B943|Q1B943_MYCSS Tax_Id=164756 SubName: Full=Precorrin-6Y
           C5,15-methyltransferase (Decarboxylating);
           EC=2.1.1.132;[Mycobacterium sp.]
          Length = 350

 Score =  480 bits (1236), Expect = e-133
 Identities = 235/347 (67%), Positives = 269/347 (77%)

Query: 47  ADRREWPSPMLPALPTLFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSV 106
           A+R EWPSP++PAL  + DD  GDVH+VASGDP+ +GIG + +R+FG  RV VLPHVSSV
Sbjct: 3   AERHEWPSPLMPALQAIRDDPAGDVHIVASGDPMLYGIGGSAVRIFGPGRVTVLPHVSSV 62

Query: 107 TLACARMGWTVPDTEVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSG 166
           TLACAR+GW V DTEVISLVTA P TAVRRGG AVVLSRD S+P  LARLLT++GRG+S 
Sbjct: 63  TLACARLGWPVQDTEVISLVTAAPRTAVRRGGHAVVLSRDESSPAALARLLTDTGRGESE 122

Query: 167 FTVLEQLGGPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDEQFSHDGQ 226
            T+LEQLGGP ERRR GTA  WSA P  DVD LNVVAV Y P+DR+   LPD  F+HDGQ
Sbjct: 123 MTLLEQLGGPEERRRTGTARSWSADPPGDVDALNVVAVRYLPDDRQLQVLPDGAFAHDGQ 182

Query: 227 ITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRA 286
           ITKQS+RAVTLAAL PRPG LLWDVG+GSGSI IEWCRS PGC A+AFERDE RR+RI A
Sbjct: 183 ITKQSMRAVTLAALAPRPGGLLWDVGAGSGSIGIEWCRSGPGCRAIAFERDETRRERIAA 242

Query: 287 NVEAFGVRVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTV 346
           N +A GV V++RGAAPE  D             +T PG+L+ C D L  GGRLV NAVT 
Sbjct: 243 NADAHGVDVEVRGAAPESLDGVPQPSAVFIGGGLTRPGLLDGCVDALPPGGRLVANAVTA 302

Query: 347 ESEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           ESE V+ QWYS+ GG+LRRYQHY+G  VG FT WRPA+PVTQW VVK
Sbjct: 303 ESEVVLVQWYSKMGGELRRYQHYRGEPVGTFTGWRPAMPVTQWVVVK 349


>tr|B1MAK5|B1MAK5_MYCA9 Tax_Id=561007 SubName: Full=Probable
           precorrin-6Y C5,15-methyltransferase CobL;[Mycobacterium
           abscessus]
          Length = 424

 Score =  441 bits (1134), Expect = e-122
 Identities = 234/397 (58%), Positives = 281/397 (70%), Gaps = 10/397 (2%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALL-DDTVIADRREWPSPMLPALPT 62
           I VVGIGADG+ GLSA SR EL RA+V+FG+ RQL LL +++++A+ R WPSP+LPALPT
Sbjct: 32  ITVVGIGADGVDGLSARSRRELHRASVIFGSLRQLELLAEESLVAECRVWPSPLLPALPT 91

Query: 63  LFDDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           +FD  G DVHV+ASGDP+ HGIG TL RLFGA RV V PH+SSV+LAC+RMGW V D E+
Sbjct: 92  MFDGLG-DVHVLASGDPMLHGIGTTLTRLFGAQRVDVHPHISSVSLACSRMGWAVNDIEI 150

Query: 123 ISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGERRRD 182
           ISLV AP  +A R GGRAVVLSR+A TP +LA+ L+ESG GDS  TV EQLGG GE    
Sbjct: 151 ISLVNAPARSARRFGGRAVVLSRNAGTPRELAQTLSESGLGDSRLTVWEQLGGAGEHSFG 210

Query: 183 GTAADWSAAPAPDVDDLNVVAVTYRPEDRRA-----HALPDEQFSHDGQITKQSIRAVTL 237
           G A  W     P  D LNV+AV Y P +  A       LP+  F HDGQITK  IRAVTL
Sbjct: 211 GVARSWDH---PLGDALNVIAVEYVPAEEVAILPLVAGLPESVFEHDGQITKHEIRAVTL 267

Query: 238 AALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRVDL 297
           AALGPRPG+ LWDVG+GSGSIA+EW RS  GC+A AFE +  RR  I AN   FGV +D+
Sbjct: 268 AALGPRPGQRLWDVGAGSGSIAVEWSRSGTGCSASAFEIEPSRRASIAANATKFGVDIDV 327

Query: 298 RGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYS 357
            GAAP+ F+             VT PG+LEAC++RL  GGR+VVNAVT ESEA++ +WY 
Sbjct: 328 FGAAPDDFEQAVAPDVIFVGGGVTQPGLLEACWERLPIGGRMVVNAVTAESEALLLRWYC 387

Query: 358 EKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVKA 394
             GG+LRRY+      +GGFT+WR  LPV QWS  K+
Sbjct: 388 RYGGELRRYRVEDAAPLGGFTSWRSRLPVVQWSTEKS 424


>tr|Q7VER4|Q7VER4_MYCBO Tax_Id=1765 (cobLb)SubName: Full=Probable
           precorrin-6y methyltransferase CobLb;
           EC=2.1.1.132;[Mycobacterium bovis]
          Length = 294

 Score =  399 bits (1024), Expect = e-109
 Identities = 200/294 (68%), Positives = 225/294 (76%), Gaps = 1/294 (0%)

Query: 100 LPHVSSVTLACARMGWTVPDTEVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTE 159
           +PHVS+VTLACARMGW V DTEVISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE
Sbjct: 1   MPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTE 60

Query: 160 SGRGDSGFTVLEQLGGPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDE 219
            GRGDS F+VLEQLGGP ERRRDGTA  W+  P  DVD+LNV+AV Y P++R + A PDE
Sbjct: 61  HGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDE 119

Query: 220 QFSHDGQITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQ 279
            F+HDGQITK  IR +TLAAL PRPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+
Sbjct: 120 AFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDER 179

Query: 280 RRDRIRANVEAFGVRVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRL 339
           RR  I  N  AFGV VD+RG AP+ FD             VT PG+LEAC D L  GG L
Sbjct: 180 RRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNL 239

Query: 340 VVNAVTVESEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           V NAVTVESEA +A  YS  GG+LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 240 VANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 293


>tr|C1APZ1|C1APZ1_MYCBT Tax_Id=561275 (cobLb)SubName: Full=Putative
           precorrin-6y methyltransferase;
           EC=2.1.1.132;[Mycobacterium bovis]
          Length = 294

 Score =  399 bits (1024), Expect = e-109
 Identities = 200/294 (68%), Positives = 225/294 (76%), Gaps = 1/294 (0%)

Query: 100 LPHVSSVTLACARMGWTVPDTEVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTE 159
           +PHVS+VTLACARMGW V DTEVISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE
Sbjct: 1   MPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTE 60

Query: 160 SGRGDSGFTVLEQLGGPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDE 219
            GRGDS F+VLEQLGGP ERRRDGTA  W+  P  DVD+LNV+AV Y P++R + A PDE
Sbjct: 61  HGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDE 119

Query: 220 QFSHDGQITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQ 279
            F+HDGQITK  IR +TLAAL PRPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+
Sbjct: 120 AFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDER 179

Query: 280 RRDRIRANVEAFGVRVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRL 339
           RR  I  N  AFGV VD+RG AP+ FD             VT PG+LEAC D L  GG L
Sbjct: 180 RRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNL 239

Query: 340 VVNAVTVESEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           V NAVTVESEA +A  YS  GG+LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 240 VANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 293


>tr|A1KKB8|A1KKB8_MYCBP Tax_Id=410289 (cobLb)SubName: Full=Probable
           precorrin-6y methyltransferase CobLb [second part];
           EC=2.1.1.132;[Mycobacterium bovis]
          Length = 294

 Score =  399 bits (1024), Expect = e-109
 Identities = 200/294 (68%), Positives = 225/294 (76%), Gaps = 1/294 (0%)

Query: 100 LPHVSSVTLACARMGWTVPDTEVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTE 159
           +PHVS+VTLACARMGW V DTEVISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE
Sbjct: 1   MPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTE 60

Query: 160 SGRGDSGFTVLEQLGGPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDE 219
            GRGDS F+VLEQLGGP ERRRDGTA  W+  P  DVD+LNV+AV Y P++R + A PDE
Sbjct: 61  HGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDE 119

Query: 220 QFSHDGQITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQ 279
            F+HDGQITK  IR +TLAAL PRPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+
Sbjct: 120 AFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDER 179

Query: 280 RRDRIRANVEAFGVRVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRL 339
           RR  I  N  AFGV VD+RG AP+ FD             VT PG+LEAC D L  GG L
Sbjct: 180 RRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNL 239

Query: 340 VVNAVTVESEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           V NAVTVESEA +A  YS  GG+LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 240 VANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 293


>tr|D6FVV0|D6FVV0_MYCTU Tax_Id=611304 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis K85]
          Length = 294

 Score =  399 bits (1024), Expect = e-109
 Identities = 200/294 (68%), Positives = 225/294 (76%), Gaps = 1/294 (0%)

Query: 100 LPHVSSVTLACARMGWTVPDTEVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTE 159
           +PHVS+VTLACARMGW V DTEVISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE
Sbjct: 1   MPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTE 60

Query: 160 SGRGDSGFTVLEQLGGPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDE 219
            GRGDS F+VLEQLGGP ERRRDGTA  W+  P  DVD+LNV+AV Y P++R + A PDE
Sbjct: 61  HGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDE 119

Query: 220 QFSHDGQITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQ 279
            F+HDGQITK  IR +TLAAL PRPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+
Sbjct: 120 AFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDER 179

Query: 280 RRDRIRANVEAFGVRVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRL 339
           RR  I  N  AFGV VD+RG AP+ FD             VT PG+LEAC D L  GG L
Sbjct: 180 RRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNL 239

Query: 340 VVNAVTVESEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           V NAVTVESEA +A  YS  GG+LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 240 VANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 293


>tr|D6FCL0|D6FCL0_MYCTU Tax_Id=611303 SubName: Full=Precorrin-6y
           methyltransferase cobL;[Mycobacterium tuberculosis
           CPHL_A]
          Length = 294

 Score =  399 bits (1024), Expect = e-109
 Identities = 200/294 (68%), Positives = 225/294 (76%), Gaps = 1/294 (0%)

Query: 100 LPHVSSVTLACARMGWTVPDTEVISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTE 159
           +PHVS+VTLACARMGW V DTEVISLVTA PHTAVRRGGRA+VLS D STP  LA LLTE
Sbjct: 1   MPHVSAVTLACARMGWNVYDTEVISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTE 60

Query: 160 SGRGDSGFTVLEQLGGPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAHALPDE 219
            GRGDS F+VLEQLGGP ERRRDGTA  W+  P  DVD+LNV+AV Y P++R + A PDE
Sbjct: 61  HGRGDSKFSVLEQLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDERTSWA-PDE 119

Query: 220 QFSHDGQITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQ 279
            F+HDGQITK  IR +TLAAL PRPG+ LWDVG+GSG+IA++WCRS PGCTAVAFERDE+
Sbjct: 120 AFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDER 179

Query: 280 RRDRIRANVEAFGVRVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRL 339
           RR  I  N  AFGV VD+RG AP+ FD             VT PG+LEAC D L  GG L
Sbjct: 180 RRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNL 239

Query: 340 VVNAVTVESEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           V NAVTVESEA +A  YS  GG+LRR+QHY G  +GGFT WRP LPVTQWSV K
Sbjct: 240 VANAVTVESEAALAHAYSRLGGELRRFQHYLGEPLGGFTGWRPQLPVTQWSVTK 293


>tr|C1ARY6|C1ARY6_RHOOB Tax_Id=632772 (cobL)SubName:
           Full=Precorrin-6Y C5,15-methyltransferase;
           EC=2.1.1.132;[Rhodococcus opacus]
          Length = 411

 Score =  374 bits (959), Expect = e-101
 Identities = 212/404 (52%), Positives = 257/404 (63%), Gaps = 18/404 (4%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTL 63
           I+VVGIGADG  GLS ++R E+  A VV G+ RQLAL+ +T  A R  WPSP++PALP L
Sbjct: 5   IVVVGIGADGWDGLSPSARREIEVADVVMGSGRQLALIPETP-ALRVAWPSPLVPALPGL 63

Query: 64  FDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           F+   G  V V+ASGDP+ HGIG TL+ L GA+RVRV+PH SS TLACAR+GW   +T V
Sbjct: 64  FEQHHGRRVCVLASGDPMFHGIGVTLVNLLGAERVRVIPHPSSATLACARLGWAAHETPV 123

Query: 123 ISLVTAPPHTAVRR---GGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGER 179
           ISLV  P    +       R +VLSRD  TP  +A LLT  G G S  TVL +LGGP E 
Sbjct: 124 ISLVNRPVDALLPELADATRLLVLSRDEHTPAAVADLLTGRGFGPSRLTVLGELGGPDES 183

Query: 180 RRDGTAADWSAAPAPDVDDLNVVAVTYRPED-----RRAHALPDEQFSHDGQITKQSIRA 234
           R DGTA+ WS  P P    LNV+A+  R E       R   LPD  F+ DGQ+TK  IRA
Sbjct: 184 RLDGTASVWSHGPGPR---LNVIAIDCRAESGAVRLTRLPGLPDAAFTGDGQMTKHEIRA 240

Query: 235 VTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGV- 293
           +TL AL P  GELLWDVG GSG++AIEW R+ P C AV FER   R D+I AN  A GV 
Sbjct: 241 LTLCALAPAAGELLWDVGGGSGTVAIEWMRTHPRCRAVTFERSAARVDQIEANASALGVP 300

Query: 294 RVDLRGAAPECFDXXXXXXXXXXXXXVTG----PGVLEACFDRLSTGGRLVVNAVTVESE 349
            + + G AP  F+             V G     G+L  C+ RL  GGR+V NAVT ESE
Sbjct: 301 SLTVFGDAPAAFEDVPPASSVPDAIFVGGGVTQDGLLGECWSRLRVGGRMVANAVTAESE 360

Query: 350 AVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           A++ QW+S+ GG LR++Q Y+G  +GGFTAWRP LPV QWSV K
Sbjct: 361 ALLLQWFSKCGGQLRKFQVYRGEPLGGFTAWRPQLPVAQWSVTK 404


>tr|D2AR10|D2AR10_STRRD Tax_Id=479432 SubName: Full=Precorrin-6Y
           C(5,15)-methyltransferase (Decarboxylating);
           EC=2.1.1.132;[Streptosporangium roseum]
          Length = 407

 Score =  369 bits (947), Expect = e-100
 Identities = 212/402 (52%), Positives = 249/402 (61%), Gaps = 15/402 (3%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           L++VVGIGADG  GLSAA+R EL  A V+ G+ RQLAL+ +   A+R  WPSPMLPALP 
Sbjct: 4   LVMVVGIGADGWAGLSAAARRELHAAEVLMGSARQLALVPEPT-AERVAWPSPMLPALPA 62

Query: 63  LFDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTE 121
           LF    G  V V+ASGDP+ HGIG TL+RL G DRVRVLPH SS +LACAR+GW V   E
Sbjct: 63  LFASHRGRRVCVLASGDPMFHGIGTTLVRLLGTDRVRVLPHPSSASLACARLGWAVDRVE 122

Query: 122 VISLVTAPP---HTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGE 178
           V+S+VT P    H AV  G R +VLS D  TP  +A LL   G G S  TVLE+LG   E
Sbjct: 123 VVSVVTRPVESVHAAVHEGRRVLVLSADGRTPARVAALLAARGYGGSTMTVLERLGAAEE 182

Query: 179 RRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAH-----ALPDEQFSHDGQITKQSIR 233
           R   GTA  WS    P   DLNVVA+  R +           LPDE F HDGQ+TK+ +R
Sbjct: 183 RVISGTAGGWSL---PVAHDLNVVALECRADAGTVPLPCVPGLPDEAFEHDGQLTKREVR 239

Query: 234 AVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGV 293
           AVTL+ L P PGELLWDVG+G+GSIAIEW R  P   AVA E   +R  RI  N    GV
Sbjct: 240 AVTLSRLAPVPGELLWDVGAGAGSIAIEWMRGHPANRAVAVESHPERAARISRNAAGLGV 299

Query: 294 --RVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAV 351
                + G AP                 VT PGV+E C++ L  GGRLV NAVTVESEAV
Sbjct: 300 PGLNVVTGPAPAALAGLEPPEAVFIGGGVTVPGVVEECWEALRPGGRLVANAVTVESEAV 359

Query: 352 VAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           +A W+ E GGDL R    +   VGGFT WRP +PVT W+ +K
Sbjct: 360 LASWHGELGGDLVRLAVSRAAPVGGFTGWRPMMPVTTWTAIK 401


>tr|Q5YUY8|Q5YUY8_NOCFA Tax_Id=37329 (cobL)SubName: Full=Putative
           precorrin 6B methyltransferase;[Nocardia farcinica]
          Length = 415

 Score =  365 bits (937), Expect = 6e-99
 Identities = 210/403 (52%), Positives = 255/403 (63%), Gaps = 15/403 (3%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTL 63
           I VVGIGADG  GL AA+R  LA A VVFG+ RQLALL     A RR WP+P+LPAL  L
Sbjct: 16  IAVVGIGADGWAGLGAAARAALAEAEVVFGSARQLALLPVDCPAQRRAWPAPLLPALREL 75

Query: 64  FDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
                   V V+ASGDP+  GIG TL R+FGAD +RVLP  SS +LACAR+GW + +  V
Sbjct: 76  LLACADRRVGVLASGDPMFFGIGVTLARMFGADALRVLPQPSSASLACARLGWPLAEVPV 135

Query: 123 ISLVTAPPHTAVRR---GGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGER 179
           +S+V  P    +     G R +VLS D +TP  LA LL  +G G S  TVLEQLGGP ER
Sbjct: 136 VSVVGRPQAGVLPELSDGRRLLVLSADETTPAALAHLLRANGFGGSRLTVLEQLGGPDER 195

Query: 180 RRDGTAADWSAAPAPDVDDLNVVAVTYRPEDR-----RAHALPDEQFSHDGQITKQSIRA 234
              GTAADW   P    D LN+VA+    +       R   LPD  F  DGQ+TK  +RA
Sbjct: 196 IVTGTAADW---PRRSGDPLNIVAIECAADPAAVRLTRTPGLPDASFGGDGQLTKAEVRA 252

Query: 235 VTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGV- 293
           +TLAAL P PGELLWD+G GSGSIAIEWCR+ P C AV FER ++RR++I  N EA GV 
Sbjct: 253 LTLAALAPAPGELLWDIGGGSGSIAIEWCRTHPACRAVTFERLDRRREQIGRNAEALGVP 312

Query: 294 RVDLRG--AAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAV 351
           +V +RG   A    D             +T  G+L+ C+DRL  GGRLV NAVT E+EA+
Sbjct: 313 QVVVRGEVMAELAADPGAAPDAIFVGGGLTQDGLLDTCWDRLRPGGRLVANAVTAETEAL 372

Query: 352 VAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVKA 394
           +    + +GG LR++Q Y+   +GGFTAWRP LPV QWSVVKA
Sbjct: 373 LVDSAARRGGALRKFQIYRAEPLGGFTAWRPQLPVAQWSVVKA 415


>tr|D5PLJ9|D5PLJ9_COREQ Tax_Id=525370 (cobL)SubName:
           Full=Precorrin-6y C5,15-methyltransferase;
           EC=2.1.1.132;[Rhodococcus equi ATCC 33707]
          Length = 420

 Score =  362 bits (930), Expect = 4e-98
 Identities = 204/401 (50%), Positives = 254/401 (63%), Gaps = 15/401 (3%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTL 63
           I+VVGIGADG  GL+  ++  +  A V+ G+ RQL L+ ++  A R  WPSPMLPALP L
Sbjct: 15  IVVVGIGADGWDGLAPRAQAAIRDAEVLMGSTRQLELIPESA-AKRVAWPSPMLPALPAL 73

Query: 64  FDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           FD+     V V+ASGDP+ HGIG TL R+ GA+R+ V+ H SSV+LACAR+GW + +T  
Sbjct: 74  FDEHRDRRVCVLASGDPMFHGIGVTLGRVLGAERLHVIAHPSSVSLACARLGWPLHETTT 133

Query: 123 ISLVTAPPHTAVRR---GGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGER 179
           +SLV     T       G R +VL+ D  TP  +ARLLT  G GDS   VLEQLGGP E 
Sbjct: 134 VSLVNRDVSTLAASLVDGQRLLVLANDEHTPAAVARLLTAHGFGDSTLVVLEQLGGPAEH 193

Query: 180 RRDGTAADWSAAPAPDVDDLNVVAVTYRPEDR-----RAHALPDEQFSHDGQITKQSIRA 234
             +G A  W  AP    D LNV+A+  R  D      R   LPD  +  DGQ+TK  +RA
Sbjct: 194 VVEGRAGGWDRAPG---DPLNVIALELRASDAALRLTRTPGLPDAAYRGDGQMTKHEVRA 250

Query: 235 VTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGV- 293
           +TL+AL P PGELLWDVG GSG+I IEW R+ P C AVAFERD  R  +I  N    GV 
Sbjct: 251 LTLSALAPAPGELLWDVGGGSGTIGIEWMRTDPRCRAVAFERDPARVAQIVDNAARLGVP 310

Query: 294 RVDLRGAAPECF-DXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVV 352
            + + G+AP  F D             VT  G+L+ C+ RL  GGR+VVNAVT ESEA+V
Sbjct: 311 TLRVLGSAPAAFADEASDPDAVFVGGGVTQDGMLDDCWTRLRPGGRMVVNAVTAESEALV 370

Query: 353 AQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
            QW++  GGDLR++Q Y+G  +GGFTAWRP LPV QWSVVK
Sbjct: 371 LQWHARLGGDLRKFQIYRGEPLGGFTAWRPQLPVAQWSVVK 411


>tr|Q0SIH5|Q0SIH5_RHOSR Tax_Id=101510 (cobL)SubName:
           Full=Precorrin-6Y C(5,15)-methyltransferase
           (Decarboxylating); EC=2.1.1.132;[Rhodococcus sp.]
          Length = 411

 Score =  362 bits (928), Expect = 6e-98
 Identities = 207/404 (51%), Positives = 255/404 (63%), Gaps = 18/404 (4%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTL 63
           I+VVGIGADG  GLS ++R  +  A VV G+ RQL LL ++  A R  WPSP++PALP L
Sbjct: 5   IVVVGIGADGWDGLSPSARRAVEHADVVMGSGRQLGLLPESP-ALRVAWPSPLVPALPGL 63

Query: 64  FDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
           F+      V V+ASGDP+ HGIG TL+ L GADRVRV+PH SS TLACAR+GW   +T V
Sbjct: 64  FEQHHDRRVCVLASGDPMFHGIGVTLVDLLGADRVRVIPHPSSATLACARLGWAAHETPV 123

Query: 123 ISLVTAPPHTAVRRGG---RAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGER 179
           +SLV       +   G   R +VLSRD  TP  +A LLTE G G S  +VL +LGGP E 
Sbjct: 124 VSLVNRHVDLLLPALGDHTRLLVLSRDEHTPAAVAELLTEHGFGPSRLSVLGELGGPDES 183

Query: 180 RRDGTAADWSAAPAPDVDDLNVVAVTYRPED-----RRAHALPDEQFSHDGQITKQSIRA 234
           R DGTA+ WS  P      LNV+A+  R +       R   LPD  F+ DGQ+TK  IRA
Sbjct: 184 RLDGTASAWSHEPGAR---LNVIAIDCRADSGTLRLTRMPGLPDIAFTGDGQMTKHEIRA 240

Query: 235 VTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGV- 293
           +TL AL P  GELLWDVG GSG++AIEW R+ P C AV FER   R D+I +N  A GV 
Sbjct: 241 LTLCALAPAAGELLWDVGGGSGTVAIEWMRTHPLCRAVTFERSAARVDQIESNAAALGVP 300

Query: 294 RVDLRGAAPECFDXXXXXXXXXXXXXVTG----PGVLEACFDRLSTGGRLVVNAVTVESE 349
            + + G AP  F+             V G     G+L+ C+ RL  GGR+VVNAVT ESE
Sbjct: 301 SLAVFGDAPAAFEDVPPELSTPDAIFVGGGVTQDGLLDECWSRLRVGGRMVVNAVTAESE 360

Query: 350 AVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           A++ QW+S  GG LR++Q Y+G  +GGFTAWRP LPV QWSV K
Sbjct: 361 ALLLQWFSNCGGQLRKFQVYRGEPLGGFTAWRPQLPVAQWSVTK 404


>tr|A4FM52|A4FM52_SACEN Tax_Id=405948 (cobL)SubName:
           Full=Precorrin-6Y C(5,15)-methyltransferase
           (Decarboxylating); EC=2.1.1.132;[Saccharopolyspora
           erythraea]
          Length = 428

 Score =  355 bits (912), Expect = 5e-96
 Identities = 206/404 (50%), Positives = 249/404 (61%), Gaps = 17/404 (4%)

Query: 2   KLIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALP 61
           + + VVGIGADG  GL+  +R  +A A V+FG+ RQL L+ +     R  WPSP+LPALP
Sbjct: 7   EFVDVVGIGADGWEGLAPRARRAVASAEVLFGSSRQLDLVPEPA-GRRVAWPSPLLPALP 65

Query: 62  TLFDDFGG-DVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDT 120
            L  +  G  + V+ASGDP+ +GIGATL+RL G DR+RVLPH SS++LACARMGW V +T
Sbjct: 66  GLLAEHAGRSICVLASGDPMFYGIGATLVRLLGPDRLRVLPHPSSLSLACARMGWPVQET 125

Query: 121 EVISLVTAPP---HTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPG 177
            V+SLV  P    H AV+   R +VLS D +TP  +A LLT  G G S  TVL  LGG  
Sbjct: 126 AVVSLVGRPVELLHPAVQPDNRVLVLSADGATPAAVAALLTARGYGASELTVLADLGGER 185

Query: 178 ERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAH-----ALPDEQFSHDGQITKQSI 232
           E R  G+AA W     P    LNVVAV  R E   AH      LPD+ F HDGQ+TK+ +
Sbjct: 186 EERISGSAATWDR---PGTGALNVVAVRCRAEPSAAHLPRVPGLPDDAFEHDGQLTKRDV 242

Query: 233 RAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFG 292
           RA TLA L P PG+LLWDVG+G+GSIAIEW R  P   A+A E  E R  RI  N  A G
Sbjct: 243 RASTLARLAPAPGQLLWDVGAGAGSIAIEWMRGDPANRAIAVEHREDRAARIARNATALG 302

Query: 293 V---RVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESE 349
           V   RV + GAAP                  T PGVLE C+D L+ GGRLVVNAVT+ESE
Sbjct: 303 VPGLRV-VTGAAPRALAGLETPDAIFVGGGATAPGVLETCWDALAPGGRLVVNAVTMESE 361

Query: 350 AVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
            +VA  Y   GG+L R        VGGFT WRP++ VTQW+V K
Sbjct: 362 VLVADRYGALGGELVRISVDHASPVGGFTGWRPSMRVTQWAVRK 405


>tr|D3M4W5|D3M4W5_9ACTO Tax_Id=656024 SubName: Full=Precorrin-6y
           C5,15-methyltransferase (Decarboxylating), CbiE subunit;
           EC=2.1.1.132;[Frankia symbiont of Datisca glomerata]
          Length = 477

 Score =  354 bits (909), Expect = 1e-95
 Identities = 207/414 (50%), Positives = 248/414 (59%), Gaps = 24/414 (5%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           L++VVG+GADG  GL+ A+R+ L    V+ G+ RQL L+   V   R EWP+P++PALP 
Sbjct: 37  LVVVVGVGADGWGGLTEAAREALRAGQVLMGSRRQLGLVPADVGGRRVEWPTPLVPALPG 96

Query: 63  LFDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTE 121
           L  +  G  V  +ASGDP+  G+G TL+RL GA RVRVLPH SSV+LACAR+GW +   +
Sbjct: 97  LLAEHAGARVCCLASGDPMFFGLGTTLVRLLGARRVRVLPHPSSVSLACARLGWAMDAVD 156

Query: 122 VISLVTAP---PHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGE 178
           V+SLV  P    H AV+ G R +VL  D   P  LA LL   G G S FTVLE LG   E
Sbjct: 157 VVSLVGRPLSAVHPAVQPGRRLIVLCADGHGPAALAGLLVGRGYGGSPFTVLENLGADDE 216

Query: 179 RRRDGTAADWSAAPAPD-----------VDDLNVVAVTYRPEDRRAH-----ALPDEQFS 222
           R R GTAA W  +  P            V DLN+VAV   P     H      LPD  F 
Sbjct: 217 RARAGTAASWCGSDEPGGGQHSGKRGDGVADLNLVAVECVPGPDADHLPRTAGLPDGAFE 276

Query: 223 HDGQITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRD 282
           HDGQ+TK+ +RAVTLA LGP PG+LLWDVG+GSGSIAIEW R+ P C AVA E    R  
Sbjct: 277 HDGQLTKREVRAVTLARLGPAPGQLLWDVGAGSGSIAIEWMRTHPACRAVAVEPQPDRVA 336

Query: 283 RIRANVEAF---GVRVDLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRL 339
           RI  N +A    G+RV +   AP                 +T  GVLE C+  L  GGRL
Sbjct: 337 RILRNADALGAPGLRV-VGSPAPAALAGLPTPDAVFVGGGLTTAGVLERCWAALPPGGRL 395

Query: 340 VVNAVTVESEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           V NAVTVESEAV+A W++  GGDL R    +   VGGFT WRP LPVTQWSV K
Sbjct: 396 VANAVTVESEAVLAGWHASHGGDLVRLAVARAAPVGGFTGWRPMLPVTQWSVTK 449


>tr|D6AXX4|D6AXX4_9ACTO Tax_Id=457425 SubName: Full=Precorrin-6Y
           C(5,15)-methyltransferase;[Streptomyces albus J1074]
          Length = 440

 Score =  352 bits (904), Expect = 4e-95
 Identities = 202/401 (50%), Positives = 241/401 (60%), Gaps = 14/401 (3%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTL 63
           + VVGIGADG  GL  A R+ LA A VV G PRQL LL      +R  WPSP+ PA+P L
Sbjct: 38  VTVVGIGADGWAGLGPAGREALAAAEVVVGGPRQLDLLPPECAGERVAWPSPLRPAVPKL 97

Query: 64  FDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
             +  G  + V+ASGDP+ +GIG  L    G   + VLPH SSV+ ACARMGW + D EV
Sbjct: 98  LAEHAGRRLAVLASGDPMFYGIGRALAEEAGPAALHVLPHPSSVSYACARMGWAMQDVEV 157

Query: 123 ISLVTAPPHT---AVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGER 179
           +S V   P     A+  G R +VL+ DA+TP+ +A LL E G G S  TVLEQLGGP E 
Sbjct: 158 VSAVGRDPAALAGALHDGRRVLVLAPDAATPSRIAELLRERGYGPSRMTVLEQLGGPAEH 217

Query: 180 RRDGTAADWSAAPAPDVDDLNVVAVTY-----RPEDRRAHALPDEQFSHDGQITKQSIRA 234
           R DG A  WSA   P  D LNVVAV        P       LPD+ + HDGQ+TK+ +RA
Sbjct: 218 RVDGVAGTWSA---PAGDPLNVVAVECVRAAGTPRLPVVPGLPDDAYEHDGQLTKKYVRA 274

Query: 235 VTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGV- 293
            TLAAL P PGELLWDVG GSGSIA+EW R+   C AV+ ERD  R  RI  N  A GV 
Sbjct: 275 ATLAALAPAPGELLWDVGGGSGSIAVEWLRAHRACRAVSVERDPVRAGRITRNARALGVP 334

Query: 294 RVD-LRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVV 352
           R+  + GAAP                 +TG G+LE C+  L TGGRLV N VT+ESEA++
Sbjct: 335 RLKVVTGAAPGALAGLPVPDAVFIGGGLTGAGLLETCWAALPTGGRLVANTVTLESEALL 394

Query: 353 AQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
            +WY   GG+L R    Q   VG FT WR A+PVTQWSV K
Sbjct: 395 TEWYRRHGGELTRLAVAQAVPVGSFTGWRQAMPVTQWSVTK 435


>tr|D2Q4R1|D2Q4R1_KRIFD Tax_Id=479435 SubName: Full=Precorrin-6y
           C5,15-methyltransferase (Decarboxylating), CbiE subunit;
           EC=2.1.1.132;[Kribbella flavida]
          Length = 399

 Score =  351 bits (901), Expect = 9e-95
 Identities = 199/400 (49%), Positives = 249/400 (62%), Gaps = 15/400 (3%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTL 63
           ++VVG+GADG  GLS A+R  +  A V+ G+ RQL L+ D   +++  WPSP+  +LP L
Sbjct: 5   LVVVGVGADGWHGLSPAARAAIEGAEVLMGSARQLQLVPDGA-SEKIAWPSPLSESLPGL 63

Query: 64  FDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
               G   + V+ASGDP  HGIG TL RL GA  VRV+PH SSV+LACAR+GW     EV
Sbjct: 64  LATHGARRICVLASGDPTFHGIGTTLTRLLGAGAVRVIPHPSSVSLACARLGWPQDQVEV 123

Query: 123 ISLVTAP---PHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGER 179
           ISLV  P    H  V+ G R V+LS  A TPT++A LLTE G G S F VLEQLG   ER
Sbjct: 124 ISLVGHPLELVHPQVQPGRRLVILSWGAHTPTEVAGLLTERGYGGSEFIVLEQLGSADER 183

Query: 180 RRDGTAADWSAAPAPDVDDLNVVAVTYRPED-----RRAHALPDEQFSHDGQITKQSIRA 234
            R  +A DW      DVD LNV+ V  + +        +  LPD+ +  DGQ+TK+ +RA
Sbjct: 184 IRTSSARDWDG----DVDPLNVIGVLCQADPGAPLLSTSPGLPDDAYESDGQLTKREVRA 239

Query: 235 VTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVR 294
           VTL+ L P PG+LLWDVG G+GSIAIEW R  P C AVA ERD  R  R+  N  + GV 
Sbjct: 240 VTLSRLAPVPGQLLWDVGGGAGSIAIEWSRHHPTCRAVAIERDPDRAKRLDRNAVSLGVV 299

Query: 295 V-DLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVA 353
           V  + GAAPE                 T PGVLEAC+  L+ GGRLV+N VT+E+E+++A
Sbjct: 300 VRTVVGAAPEALAELETPDAVFVGGGGTVPGVLEACWQALAPGGRLVMNGVTLETESLIA 359

Query: 354 QWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           +WY+E GGDL R    +   VGG T WRPA+PVT WSV K
Sbjct: 360 RWYAELGGDLVRLSVQRASPVGGMTGWRPAMPVTIWSVTK 399


>tr|A8KXX2|A8KXX2_FRASN Tax_Id=298653 SubName: Full=Precorrin-6y
           C5,15-methyltransferase (Decarboxylating), CbiE subunit;
           EC=2.1.1.132;[Frankia sp.]
          Length = 446

 Score =  350 bits (897), Expect = 3e-94
 Identities = 204/426 (47%), Positives = 250/426 (58%), Gaps = 36/426 (8%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           ++ VVGIG DG  GL+ A+RDEL+RA V+ G+ RQL LL   V   R  WPSP++PAL  
Sbjct: 18  VVTVVGIGDDGWDGLTRAARDELSRAEVIMGSERQLDLLPAAVRGRRVRWPSPLVPALAK 77

Query: 63  LFDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTE 121
           L D   G  V  +ASGDP+  G+G TL+R  GA RVRVLPH SSV+LACAR+GW +  TE
Sbjct: 78  LVDTHAGARVCALASGDPMFFGLGTTLVRELGAARVRVLPHPSSVSLACARLGWALDTTE 137

Query: 122 VISLVTAP---PHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGE 178
           ++SLV  P    H A+  G R +VLS D  TP  L RLLT+ G G S  T+ E LGGP E
Sbjct: 138 IVSLVARPLAAVHPALTAGRRLLVLSADRRTPAQLCRLLTDRGFGGSTVTIFEHLGGPAE 197

Query: 179 RRRD-------------------GTAADWSAAPAPDVDDLNVVAV--TYRPEDR---RAH 214
           RRRD                    T+AD S A      DLN+VA+  T  PE R   R  
Sbjct: 198 RRRDTRASVLGGARSEARVDEGAATSADGSGAGPDSTADLNLVALELTAGPETRHLPRIP 257

Query: 215 ALPDEQFSHDGQITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAF 274
            LPD+ F HDGQ+TK+ IRAVTLA L P PGELLWDVG+G GSI+IEW R+ P C AVA 
Sbjct: 258 GLPDDVFEHDGQLTKREIRAVTLARLAPAPGELLWDVGAGCGSISIEWMRAHPACRAVAV 317

Query: 275 ERDEQRRDRIRANVEAFGV---RVDLRGAAPECFDXXXXXXXXXXXXXV----TGPGVLE 327
           E    R   I  N EA GV   RV +   AP   D             +    T PG + 
Sbjct: 318 EPHADRVRMIGRNAEALGVPALRV-VAATAPAALDDLADETGVPDAVFIGGGLTAPGTIT 376

Query: 328 ACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVT 387
             ++ L  GGRLV NAVT+ESE ++A+W++  GGDL R    +   VGGF  WRP +PVT
Sbjct: 377 RSWEALRPGGRLVANAVTIESEVILAKWHARHGGDLIRLAVSRASPVGGFAGWRPMMPVT 436

Query: 388 QWSVVK 393
           QW+  +
Sbjct: 437 QWAATR 442


>tr|C3JTA2|C3JTA2_RHOER Tax_Id=596309 SubName: Full=Precorrin-6Y
           C(5,15)-methyltransferase; EC=2.1.1.132;[Rhodococcus
           erythropolis SK121]
          Length = 427

 Score =  348 bits (894), Expect = 6e-94
 Identities = 201/406 (49%), Positives = 254/406 (62%), Gaps = 17/406 (4%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRRE-----WPSPMLP 58
           +++VGIGADG  GLS +++  +  A V+ G+PRQL L+  T +  RR      WPSPM+P
Sbjct: 6   VVIVGIGADGWDGLSESAKGAILGAEVLMGSPRQLDLVPATHLGARRAPTRLTWPSPMIP 65

Query: 59  ALPTLF-DDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTV 117
           ALP++F ++    V V+ASGDP+ HG+G TL+RL GAD VRV+ H SSV LA ARMGW  
Sbjct: 66  ALPSMFAENADRRVCVLASGDPMFHGLGVTLVRLLGADNVRVISHPSSVALASARMGWAS 125

Query: 118 PDTEVISLVTAPPHT---AVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLG 174
            + +V+SLV     T   +V  G R +VLS   STP ++ARLL+ +G G S  TVL QLG
Sbjct: 126 AEIDVVSLVNRDSATVLASVTDGARLLVLSNGRSTPGEVARLLSGAGFGRSIVTVLAQLG 185

Query: 175 GPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPED-----RRAHALPDEQFSHDGQITK 229
           G GE R    A +W  A   DVD LNV+AV     D      R   LPD  F  DGQ+TK
Sbjct: 186 GAGESRTVTVADEWDHADE-DVDALNVLAVECIAADPLLRLTRIPGLPDAAFVGDGQMTK 244

Query: 230 QSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVE 289
           Q IRA+TL AL P PGE LWDVG GSG++AIEW R+ P CTA  FE+  +R  +I  N  
Sbjct: 245 QEIRALTLCALAPAPGEHLWDVGGGSGTVAIEWMRTHPRCTATTFEKVARRVSQIGVNAL 304

Query: 290 AFGV-RVDLRGAAPECF-DXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVE 347
             GV  ++++GAAPE F D             VT PG+LEAC+ +LS GGRLV NAVT E
Sbjct: 305 NLGVPALNVKGAAPEAFADEVRRPDAVFVGGGVTQPGMLEACWGQLSVGGRLVANAVTAE 364

Query: 348 SEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           SE+++  W S  GG LRR+Q  +   +G F  WRP LPV QWSV K
Sbjct: 365 SESLLLGWMSRHGGTLRRFQVQRAEPLGTFNVWRPQLPVVQWSVTK 410


>tr|C0ZZT3|C0ZZT3_RHOE4 Tax_Id=234621 (cobL)SubName:
           Full=Precorrin-6Y C5,15-methyltransferase;
           EC=2.1.1.132;[Rhodococcus erythropolis]
          Length = 427

 Score =  347 bits (891), Expect = 1e-93
 Identities = 200/407 (49%), Positives = 254/407 (62%), Gaps = 17/407 (4%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRRE-----WPSPMLP 58
           +++VGIGADG  GLS +++  +  A V+ G+PRQL L+    +  RR      WPSPM+P
Sbjct: 6   VVIVGIGADGWEGLSESAKGAILGAEVLMGSPRQLDLVPAAHLGARRAPTRLTWPSPMIP 65

Query: 59  ALPTLF-DDFGGDVHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTV 117
           ALP++F ++    V V+ASGDP+ HG+G TL+RL GAD VRV+ H SSV LA ARMGW  
Sbjct: 66  ALPSMFAENADRKVCVLASGDPMFHGLGVTLVRLLGADNVRVISHPSSVALASARMGWAS 125

Query: 118 PDTEVISLVTAPPHT---AVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLG 174
            + +V+SLV     T   AV  G R +VLS   STP ++ARLL+ +G G S  TVL QLG
Sbjct: 126 SEVDVVSLVNRDSATVLAAVVDGARLLVLSNGRSTPGEVARLLSGAGFGRSTLTVLAQLG 185

Query: 175 GPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDR-----RAHALPDEQFSHDGQITK 229
           G  E R    A +W  A   DVD LNV+AV     D      R   LPD  F  DGQ+TK
Sbjct: 186 GAEESRTVTVADEWDHADE-DVDALNVLAVECISVDHPLRLTRIPGLPDAAFVGDGQMTK 244

Query: 230 QSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVE 289
           Q IRA+TL AL P PGE LWDVG GSG++AIEW R+ P CTA AFE+   R  +I AN  
Sbjct: 245 QEIRALTLCALAPAPGEHLWDVGGGSGTVAIEWMRTHPRCTATAFEKVASRVSQIGANAL 304

Query: 290 AFGV-RVDLRGAAPECF-DXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVE 347
             GV  + ++G APE F +             VT PG+LEAC+++LS GGRLV NAVT E
Sbjct: 305 NLGVPALAVKGTAPEAFAEEVRRPDAVFVGGGVTQPGMLEACWEQLSVGGRLVANAVTAE 364

Query: 348 SEAVVAQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVKA 394
           SE+++  W S +GG LRR+Q  +   +G F  WRP LPV QWSV K+
Sbjct: 365 SESLLLGWMSRQGGTLRRFQVQRAEPLGAFNVWRPQLPVVQWSVTKS 411


>tr|B1VNX8|B1VNX8_STRGG Tax_Id=455632 SubName: Full=Putative
           methyltransferase;[Streptomyces griseus subsp. griseus]
          Length = 425

 Score =  342 bits (877), Expect = 5e-92
 Identities = 194/401 (48%), Positives = 234/401 (58%), Gaps = 14/401 (3%)

Query: 4   IIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPTL 63
           + VVGIGADG PGLS  +R  L  A V+ G  RQL LL       R  WPSP+ PA+P L
Sbjct: 14  VSVVGIGADGWPGLSGTARGALREAEVLIGGARQLDLLPPECAGVRVAWPSPLRPAVPRL 73

Query: 64  FDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTEV 122
             +     V V+ASGDP+ +GIG  L +  G   +RVLPH SSV  ACAR+GW V DTEV
Sbjct: 74  LAEHRERRVAVLASGDPMFYGIGRALAQELGPQGLRVLPHPSSVAYACARLGWPVEDTEV 133

Query: 123 ISLVTAPPH---TAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGPGER 179
           ++LV  P      ++  G R +VLS DASTP  +A LLTE G G SG  VLEQLG   E 
Sbjct: 134 VTLVGRPAARLAASLYEGRRLLVLSADASTPATVAALLTERGFGPSGLRVLEQLGAADEA 193

Query: 180 RRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRRAH-----ALPDEQFSHDGQITKQSIRA 234
             DG A  W   P    D LNV+A+  R             LPDE + HDGQ+TK+ +RA
Sbjct: 194 CADGLAESWEHPPG---DRLNVIAIDCRASADALRLGAVPGLPDEAYEHDGQLTKRHVRA 250

Query: 235 VTLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVR 294
            TL  L P PGELLWDVG GSGSIA+EW R+ P C AV+ ERD  R +RI  N E  GV 
Sbjct: 251 ATLGTLAPAPGELLWDVGGGSGSIAVEWLRAHPSCRAVSVERDPVRAERITRNAERLGVP 310

Query: 295 V--DLRGAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVV 352
               + G AP                 +T PG+L+AC+  L  GGRLV N VT+ESEA++
Sbjct: 311 ALKVVTGPAPAALAGLAAPDAVFIGGGLTAPGLLDACWAALRPGGRLVANTVTLESEALL 370

Query: 353 AQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           A+W+   GG+L R        VGGFT WR A+PVTQWS VK
Sbjct: 371 AEWHKAHGGELVRLAVAHAVPVGGFTGWRQAMPVTQWSAVK 411


>tr|C6WCV9|C6WCV9_ACTMD Tax_Id=446462 SubName: Full=Precorrin-6y
           C5,15-methyltransferase (Decarboxylating), CbiE subunit;
           EC=2.1.1.132;[Actinosynnema mirum]
          Length = 392

 Score =  342 bits (876), Expect = 7e-92
 Identities = 200/401 (49%), Positives = 247/401 (61%), Gaps = 31/401 (7%)

Query: 3   LIIVVGIGADGMPGLSAASRDELARATVVFGAPRQLALLDDTVIADRREWPSPMLPALPT 62
           +I VVG+GADG  GL+  +R E+  A V+ G+ RQL L+       R  WPSP+LPALP 
Sbjct: 10  VITVVGLGADGWDGLTGHARHEITSAEVLMGSARQLDLVPGGFT--RVAWPSPLLPALPD 67

Query: 63  LFDDFGGD-VHVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTE 121
           L     G  V V+ASGDPL HGIGATL+RL GADRV V+PH SS +LACAR+GW +  TE
Sbjct: 68  LLAAHAGRRVCVLASGDPLFHGIGATLVRLLGADRVAVVPHPSSASLACARLGWALDRTE 127

Query: 122 VISLVTAP-----PHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLEQLGGP 176
           V+SLV  P     PH   RR  R ++L  D     +LA         D+  TVLEQLGGP
Sbjct: 128 VVSLVGRPTSLLVPHLQPRR--RLLLLGADPRAVAELAP--------DARITVLEQLGGP 177

Query: 177 GERRRDGTAADWSAAPAPDVDDLNVVAVTYRPED-RRAHALPDEQFSHDGQITKQSIRAV 235
            ER       D  AA     D L+V+AV   P    RA  LPD+ F HDGQITK+ +RAV
Sbjct: 178 DERVHH----DLDAA-----DPLHVLAVECGPGGLSRAPGLPDDAFEHDGQITKREVRAV 228

Query: 236 TLAALGPRPGELLWDVGSGSGSIAIEWCRSAPGCTAVAFERDEQRRDRIRANVEAFGVRV 295
           +LA LGPR GELLWDVG+G+GSIA+EWCR+ P C A+A E+  +R  R+  N  A GV  
Sbjct: 229 SLALLGPRVGELLWDVGAGAGSIAVEWCRTHPACRALAVEKHPERAARVTRNATALGVPT 288

Query: 296 DLR---GAAPECFDXXXXXXXXXXXXXVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVV 352
            +R   GA+P+  D             VT PGV+E C+  L  GGRLV NAVT+ESEAV+
Sbjct: 289 AVRVVEGASPDALDGLERPDAVFVGGGVTAPGVVERCWAALKPGGRLVANAVTIESEAVL 348

Query: 353 AQWYSEKGGDLRRYQHYQGGAVGGFTAWRPALPVTQWSVVK 393
           A+W++E GG L R    +   VGGFT WRP +PVT W+V K
Sbjct: 349 ARWHAELGGALTRLSVSRAAPVGGFTGWRPHMPVTVWAVTK 389


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.320    0.137    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 3,400,304,582
Number of extensions: 146973905
Number of successful extensions: 358337
Number of sequences better than 10.0: 1262
Number of HSP's gapped: 359508
Number of HSP's successfully gapped: 1278
Length of query: 394
Length of database: 4,236,830,644
Length adjustment: 140
Effective length of query: 254
Effective length of database: 2,485,729,684
Effective search space: 631375339736
Effective search space used: 631375339736
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 82 (36.2 bits)