BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_4277
         (241 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|A0R065|COBS_MYCS2 Tax_Id=246196 (cobS)RecName: Full=Cobalamin...   253   2e-65
sp|A1TB16|COBS_MYCVP Tax_Id=350058 (cobS)RecName: Full=Cobalamin...   184   1e-44
sp|A4TBJ8|COBS_MYCGI Tax_Id=350054 (cobS)RecName: Full=Cobalamin...   169   2e-40
sp|Q10397|COBS_MYCTU Tax_Id=1773 (cobS)RecName: Full=Cobalamin s...   160   1e-37
sp|A5U4N6|COBS_MYCTA Tax_Id=419947 (cobS)RecName: Full=Cobalamin...   160   1e-37
sp|C1AQC3|COBS_MYCBT Tax_Id=561275 (cobS)RecName: Full=Cobalamin...   160   1e-37
sp|A1KKQ0|COBS_MYCBP Tax_Id=410289 (cobS)RecName: Full=Cobalamin...   160   1e-37
sp|Q7VEN6|COBS_MYCBO Tax_Id=1765 (cobS)RecName: Full=Cobalamin s...   160   1e-37
tr|C6DPK0|C6DPK0_MYCTK Tax_Id=478434 (cobS)RecName: Full=Cobalam...   160   1e-37
tr|A5WPH8|A5WPH8_MYCTF Tax_Id=336982 (cobS)RecName: Full=Cobalam...   160   1e-37
tr|D6FX10|D6FX10_MYCTU Tax_Id=611304 SubName: Full=Cobalamin 5-p...   160   1e-37
tr|D6FIA4|D6FIA4_MYCTU Tax_Id=611303 SubName: Full=Cobalamin 5-p...   160   1e-37
tr|D6F5Y9|D6F5Y9_MYCTU Tax_Id=611302 SubName: Full=Cobalamin-5-p...   160   1e-37
tr|D5Z577|D5Z577_MYCTU Tax_Id=537209 SubName: Full=Cobalamin 5-p...   160   1e-37
tr|D5YS15|D5YS15_MYCTU Tax_Id=515616 SubName: Full=Cobalamin syn...   160   1e-37
tr|D5YH37|D5YH37_MYCTU Tax_Id=520140 SubName: Full=Cobalamin syn...   160   1e-37
tr|D5Y5P2|D5Y5P2_MYCTU Tax_Id=520141 SubName: Full=Cobalamin syn...   160   1e-37
tr|A2VJU9|A2VJU9_MYCTU Tax_Id=348776 SubName: Full=Cobalamin 5-p...   160   1e-37
sp|Q73YK6|COBS_MYCPA Tax_Id=1770 (cobS)RecName: Full=Cobalamin s...   159   3e-37
sp|A0QEZ8|COBS_MYCA1 Tax_Id=243243 (cobS)RecName: Full=Cobalamin...   159   3e-37
tr|D6G623|D6G623_MYCTU Tax_Id=478435 SubName: Full=Cobalamin 5-p...   158   5e-37
tr|A4KIX8|A4KIX8_MYCTU Tax_Id=395095 SubName: Full=Cobalamin 5-p...   158   5e-37
sp|Q1B6S1|COBS_MYCSS Tax_Id=164756 (cobS)RecName: Full=Cobalamin...   153   1e-35
sp|A1UIA4|COBS_MYCSK Tax_Id=189918 (cobS)RecName: Full=Cobalamin...   153   1e-35
sp|A0PTP3|COBS_MYCUA Tax_Id=362242 (cobS)RecName: Full=Cobalamin...   152   3e-35
sp|B2HGX7|COBS_MYCMM Tax_Id=216594 (cobS)RecName: Full=Cobalamin...   152   3e-35
sp|A3Q1R8|COBS_MYCSJ Tax_Id=164757 (cobS)RecName: Full=Cobalamin...   152   3e-35
tr|D5ZGA5|D5ZGA5_MYCTU Tax_Id=537210 SubName: Full=Cobalamin 5-p...   135   4e-30
tr|B1MNY3|B1MNY3_MYCA9 Tax_Id=561007 (cobS)RecName: Full=Cobalam...   128   7e-28
tr|D5PP99|D5PP99_COREQ Tax_Id=525370 (cobS)SubName: Full=Cobalam...   113   2e-23
tr|D5P724|D5P724_9MYCO Tax_Id=525368 (cobS)SubName: Full=Adenosy...   110   2e-22
tr|Q0SHL3|Q0SHL3_RHOSR Tax_Id=101510 (cobS)RecName: Full=Cobalam...   107   1e-21
tr|D5XUX2|D5XUX2_MYCTU Tax_Id=515617 SubName: Full=Cobalamin 5-p...   107   1e-21
tr|C1A133|C1A133_RHOE4 Tax_Id=234621 (cobV)RecName: Full=Cobalam...   105   5e-21
tr|C6W9E6|C6W9E6_ACTMD Tax_Id=446462 (cobS)RecName: Full=Cobalam...   105   6e-21
tr|C1AUB2|C1AUB2_RHOOB Tax_Id=632772 (cobV)RecName: Full=Cobalam...   104   1e-20
tr|C3JJB0|C3JJB0_RHOER Tax_Id=596309 (cobS)SubName: Full=Cobalam...   103   2e-20
tr|A4FA93|A4FA93_SACEN Tax_Id=405948 (cobS)SubName: Full=Putativ...   100   3e-19
tr|Q5YZ46|Q5YZ46_NOCFA Tax_Id=37329 (cobS)RecName: Full=Cobalami...    94   2e-17
tr|D5UXQ7|D5UXQ7_TSUPA Tax_Id=521096 SubName: Full=Cobalamin-5-p...    93   3e-17
tr|D1SDN6|D1SDN6_9ACTO Tax_Id=644283 SubName: Full=Cobalamin 5'-...    78   1e-12
tr|A4XA08|A4XA08_SALTO Tax_Id=369723 (cobS)RecName: Full=Cobalam...    77   2e-12
tr|C4RMI3|C4RMI3_9ACTO Tax_Id=219305 SubName: Full=Cobalamin-5-p...    75   5e-12
tr|D0LAY2|D0LAY2_GORB4 Tax_Id=526226 (cobS)RecName: Full=Cobalam...    73   3e-11
tr|A8LYE0|A8LYE0_SALAI Tax_Id=391037 SubName: Full=Cobalamin-5-p...    73   3e-11

>sp|A0R065|COBS_MYCS2 Tax_Id=246196 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium smegmatis]
          Length = 241

 Score =  253 bits (645), Expect = 2e-65
 Identities = 138/221 (62%), Positives = 138/221 (62%)

Query: 1   MIRSLAGAFAFGTVLPVRASAGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSPLP 60
           MIRSLAGAFAFGTVLPVRASAGVGRGALTALP                        SPLP
Sbjct: 1   MIRSLAGAFAFGTVLPVRASAGVGRGALTALPFVGLALGALAAAVVWAGGWAFAAGSPLP 60

Query: 61  GXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXX 120
           G          TRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFG           
Sbjct: 61  GVLAVAVLLLATRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGVAAVVVVIAVQ 120

Query: 121 XLTFAELSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVALA 180
            LTFAELS                                     SQPRWVVAGWIVALA
Sbjct: 121 ALTFAELSVLAVVTAVVAGRVAVVAACRRSVPAAAGSTLGAAVAGSQPRWVVAGWIVALA 180

Query: 181 ALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           ALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD
Sbjct: 181 ALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221


>sp|A1TB16|COBS_MYCVP Tax_Id=350058 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium vanbaalenii]
          Length = 243

 Score =  184 bits (466), Expect = 1e-44
 Identities = 106/223 (47%), Positives = 113/223 (50%), Gaps = 2/223 (0%)

Query: 1   MIRSLAGAFAFGTVLPV--RASAGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           MI SL GAFAF TVLP   RA+A VGRG LTALP                        S 
Sbjct: 1   MISSLTGAFAFATVLPTPTRATAMVGRGVLTALPVAGAALGVLAAGVLWAGSWAFGDGSA 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DTVD LGCYGPPERALAVMRDG+AGPFG         
Sbjct: 61  LAGVLTVAVLLLATRGLHIDGLSDTVDALGCYGPPERALAVMRDGTAGPFGVAAVAATLL 120

Query: 119 XXXLTFAELSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVA 178
              L FA+                                       +QPRWV AGW VA
Sbjct: 121 VQSLAFAQSGWAAVFIAVVAGRVAVVAACRRGVPAAAGSTLGALVSGTQPRWVAAGWTVA 180

Query: 179 LAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +AA AV  C RPWQGPL V +A+ CS  LVAHCVRRFGGITGD
Sbjct: 181 VAAAAVPVCARPWQGPLVVALALACSAGLVAHCVRRFGGITGD 223


>sp|A4TBJ8|COBS_MYCGI Tax_Id=350054 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium gilvum]
          Length = 243

 Score =  169 bits (429), Expect = 2e-40
 Identities = 98/223 (43%), Positives = 110/223 (49%), Gaps = 2/223 (0%)

Query: 1   MIRSLAGAFAFGTVLPV--RASAGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M RSLAGAFAF TV+PV  R +A  GRG LTALP                        S 
Sbjct: 1   MTRSLAGAFAFATVMPVPSRRAAIAGRGVLTALPVVGLVLGSAAAAVCWLGTRAFGSGSV 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT D LGCYGP ERALAVMRDG AGPFG         
Sbjct: 61  LAGALTVAVLLLATRGLHIDGLSDTTDALGCYGPAERALAVMRDGRAGPFGVAAVAVTVV 120

Query: 119 XXXLTFAELSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVA 178
              + F++                                       +QP WV A W+VA
Sbjct: 121 IQSVAFSQAGWAAVLVAVAAGRVAVVVACRRGVPAAEGSTLGALVAGTQPLWVAAAWLVA 180

Query: 179 LAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +A LA  A  R WQGPLAV+VA+ CS+ +VAHCVRRFGGITGD
Sbjct: 181 IAGLATLAGERAWQGPLAVVVAVACSVVMVAHCVRRFGGITGD 223


>sp|Q10397|COBS_MYCTU Tax_Id=1773 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium tuberculosis]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>sp|A5U4N6|COBS_MYCTA Tax_Id=419947 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium tuberculosis]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>sp|C1AQC3|COBS_MYCBT Tax_Id=561275 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium bovis]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>sp|A1KKQ0|COBS_MYCBP Tax_Id=410289 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium bovis]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>sp|Q7VEN6|COBS_MYCBO Tax_Id=1765 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium bovis]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|C6DPK0|C6DPK0_MYCTK Tax_Id=478434 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium tuberculosis]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|A5WPH8|A5WPH8_MYCTF Tax_Id=336982 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium tuberculosis]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|D6FX10|D6FX10_MYCTU Tax_Id=611304 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis
           K85]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|D6FIA4|D6FIA4_MYCTU Tax_Id=611303 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis
           CPHL_A]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMPTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|D6F5Y9|D6F5Y9_MYCTU Tax_Id=611302 SubName:
           Full=Cobalamin-5-phosphate synthase;[Mycobacterium
           tuberculosis T46]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|D5Z577|D5Z577_MYCTU Tax_Id=537209 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis GM
           1503]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|D5YS15|D5YS15_MYCTU Tax_Id=515616 SubName: Full=Cobalamin
           synthase;[Mycobacterium tuberculosis 02_1987]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|D5YH37|D5YH37_MYCTU Tax_Id=520140 SubName: Full=Cobalamin
           synthase;[Mycobacterium tuberculosis EAS054]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|D5Y5P2|D5Y5P2_MYCTU Tax_Id=520141 SubName: Full=Cobalamin
           synthase;[Mycobacterium tuberculosis T85]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>tr|A2VJU9|A2VJU9_MYCTU Tax_Id=348776 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis C]
          Length = 249

 Score =  160 bits (405), Expect = 1e-37
 Identities = 97/226 (42%), Positives = 110/226 (48%), Gaps = 5/226 (2%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW 175
              L FA L+                                        +QP  VVA W
Sbjct: 121 LQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAW 180

Query: 176 IVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           +  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 LAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 226


>sp|Q73YK6|COBS_MYCPA Tax_Id=1770 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium paratuberculosis]
          Length = 251

 Score =  159 bits (402), Expect = 3e-37
 Identities = 95/228 (41%), Positives = 109/228 (47%), Gaps = 7/228 (3%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAFGTVLPV A     +GRGA+TALP                        SP
Sbjct: 1   MMRSLATAFAFGTVLPVPAGGRGPMGRGAMTALPVVGLALGALAAAVAWGGAVVFGRSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RA AVMRDGS GPFG         
Sbjct: 61  LGGLLAVAALLLITRGLHIDGVADTADGLGCYGPPDRARAVMRDGSTGPFGVAAVVVVVM 120

Query: 119 XXXLTFAELS-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVA 173
              L F+ L+                                          SQP  V A
Sbjct: 121 AQALAFSALAAGRPVPVGVAVAVFAGRVAAVLACRRTVPAAAGSSLGATVAGSQPATVAA 180

Query: 174 GWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            W+  L  +++ A PRPW GP+AVL+ +GC   LV HCVRRFGGI+GD
Sbjct: 181 AWVAVLLGMSLVAGPRPWHGPVAVLLGLGCGGVLVRHCVRRFGGISGD 228


>sp|A0QEZ8|COBS_MYCA1 Tax_Id=243243 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium avium]
          Length = 251

 Score =  159 bits (402), Expect = 3e-37
 Identities = 94/228 (41%), Positives = 109/228 (47%), Gaps = 7/228 (3%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAFGTVLP+ A     +GRGA+TALP                        SP
Sbjct: 1   MMRSLATAFAFGTVLPMPAGGRGPMGRGAMTALPVVGLALGALAAAVAWGGTVVFGRSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RA AVMRDGS GPFG         
Sbjct: 61  LGGLLAVAALLLITRGLHIDGVADTADGLGCYGPPDRARAVMRDGSTGPFGVAAVVVVVM 120

Query: 119 XXXLTFAELS-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVA 173
              L F+ L+                                          SQP  V A
Sbjct: 121 AQALAFSALAAGRPVPVGVAVAVFAGRVAAVLACRRTVPAAAGSSLGAAVAGSQPATVAA 180

Query: 174 GWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            W+  L  +++ A PRPW GP+AVL+ +GC   LV HCVRRFGGI+GD
Sbjct: 181 AWVAVLLGMSLVAGPRPWHGPVAVLLGLGCGAVLVRHCVRRFGGISGD 228


>tr|D6G623|D6G623_MYCTU Tax_Id=478435 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis
           KZN 605]
          Length = 248

 Score =  158 bits (400), Expect = 5e-37
 Identities = 96/225 (42%), Positives = 109/225 (48%), Gaps = 5/225 (2%)

Query: 2   IRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSPL 59
           +RSLA AFAF TV+P   SA   +GRG +TALP                        SPL
Sbjct: 1   MRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSPL 60

Query: 60  PGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXX 119
            G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG          
Sbjct: 61  SGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAL 120

Query: 120 XXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWI 176
             L FA L+                                        +QP  VVA W+
Sbjct: 121 QGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAWL 180

Query: 177 VALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
             L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 AVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 225


>tr|A4KIX8|A4KIX8_MYCTU Tax_Id=395095 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis
           str. Haarlem]
          Length = 248

 Score =  158 bits (400), Expect = 5e-37
 Identities = 96/225 (42%), Positives = 109/225 (48%), Gaps = 5/225 (2%)

Query: 2   IRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSPL 59
           +RSLA AFAF TV+P   SA   +GRG +TALP                        SPL
Sbjct: 1   MRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSPL 60

Query: 60  PGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXX 119
            G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG          
Sbjct: 61  SGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIAL 120

Query: 120 XXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWI 176
             L FA L+                                        +QP  VVA W+
Sbjct: 121 QGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAWL 180

Query: 177 VALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
             L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 181 AVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 225


>sp|Q1B6S1|COBS_MYCSS Tax_Id=164756 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium sp.]
          Length = 248

 Score =  153 bits (387), Expect = 1e-35
 Identities = 98/228 (42%), Positives = 110/228 (48%), Gaps = 7/228 (3%)

Query: 1   MIRSLAGAFAFGTVLPVRA--SAGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           MI SLAGAFAFGTVLPV A  +A +GRG +TALP                        S 
Sbjct: 1   MIGSLAGAFAFGTVLPVPAGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSA 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRG+HIDG  DTVDGLGCYG PERAL VMRDGSAG FG         
Sbjct: 61  LAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVG 120

Query: 119 XXXLTFAEL-----SXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVA 173
              L F+ L                                           +QP  VV 
Sbjct: 121 AQTLAFSMLPGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVVL 180

Query: 174 GWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            W+ A+AALA+ A  R WQGPL V+VA+G +  LV HCVRRFGGITGD
Sbjct: 181 VWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGD 228


>sp|A1UIA4|COBS_MYCSK Tax_Id=189918 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium sp.]
          Length = 248

 Score =  153 bits (387), Expect = 1e-35
 Identities = 98/228 (42%), Positives = 110/228 (48%), Gaps = 7/228 (3%)

Query: 1   MIRSLAGAFAFGTVLPVRA--SAGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           MI SLAGAFAFGTVLPV A  +A +GRG +TALP                        S 
Sbjct: 1   MIGSLAGAFAFGTVLPVPAGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSA 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRG+HIDG  DTVDGLGCYG PERAL VMRDGSAG FG         
Sbjct: 61  LAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVG 120

Query: 119 XXXLTFAEL-----SXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVA 173
              L F+ L                                           +QP  VV 
Sbjct: 121 AQTLAFSMLPGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVVL 180

Query: 174 GWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            W+ A+AALA+ A  R WQGPL V+VA+G +  LV HCVRRFGGITGD
Sbjct: 181 VWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGD 228


>sp|A0PTP3|COBS_MYCUA Tax_Id=362242 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium ulcerans]
          Length = 252

 Score =  152 bits (385), Expect = 3e-35
 Identities = 93/229 (40%), Positives = 107/229 (46%), Gaps = 8/229 (3%)

Query: 1   MIRSLAGAFAFGTVLPVRAS--AGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           MIRSLA A +FGTV+PV AS  A +GRGA+TALP                        SP
Sbjct: 1   MIRSLATALSFGTVIPVPASVAAPMGRGAMTALPVVGVVLGGLAAGVTWSASLVFGPVSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           LPG          TRGLHID   DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LPGLLAVAVLLLATRGLHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVV 172
                F+ LS                                           +QP  V+
Sbjct: 121 VQGSAFSTLSAAGSRGIAGIAVAVFAGRVTAVLGCRRSVPAAAGSSLGSRVAGTQPISVL 180

Query: 173 AGWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
             W+  L   ++ A PRPWQGP AV+ A+     L+ HCVRRFGGITGD
Sbjct: 181 VAWLAVLLFASLAAAPRPWQGPAAVVAAVCAGTLLIRHCVRRFGGITGD 229


>sp|B2HGX7|COBS_MYCMM Tax_Id=216594 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium marinum]
          Length = 252

 Score =  152 bits (385), Expect = 3e-35
 Identities = 93/229 (40%), Positives = 107/229 (46%), Gaps = 8/229 (3%)

Query: 1   MIRSLAGAFAFGTVLPVRAS--AGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           MIRSLA A +FGTV+PV AS  A +GRGA+TALP                        SP
Sbjct: 1   MIRSLATALSFGTVIPVPASVAAPMGRGAMTALPVVGVVLGGLAAGVTWSASLVFGPVSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           LPG          TRGLHID   DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LPGLLAVAVLLLATRGLHIDAVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVV 172
                F+ LS                                           +QP  V+
Sbjct: 121 VQGSAFSTLSAAGSRGIAGIAVAVFAGRVTAVLGCRRSVPAAAGSSLGSRVAGTQPISVL 180

Query: 173 AGWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
             W+  L   ++ A PRPWQGP AV+ A+     L+ HCVRRFGGITGD
Sbjct: 181 VAWLAVLLFASLAAAPRPWQGPAAVVAAVCAGTLLIRHCVRRFGGITGD 229


>sp|A3Q1R8|COBS_MYCSJ Tax_Id=164757 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium sp.]
          Length = 248

 Score =  152 bits (384), Expect = 3e-35
 Identities = 97/228 (42%), Positives = 110/228 (48%), Gaps = 7/228 (3%)

Query: 1   MIRSLAGAFAFGTVLPVR--ASAGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           MI SLAGAFAFGTVLPV   ++A +GRG +TALP                        S 
Sbjct: 1   MIGSLAGAFAFGTVLPVPTGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSA 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRG+HIDG  DTVDGLGCYG PERAL VMRDGSAG FG         
Sbjct: 61  LAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVG 120

Query: 119 XXXLTFAEL-----SXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVA 173
              L F+ L                                           +QP  VV 
Sbjct: 121 AQTLAFSMLPGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVVL 180

Query: 174 GWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            W+ A+AALA+ A  R WQGPL V+VA+G +  LV HCVRRFGGITGD
Sbjct: 181 VWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGD 228


>tr|D5ZGA5|D5ZGA5_MYCTU Tax_Id=537210 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis
           T17]
          Length = 223

 Score =  135 bits (340), Expect = 4e-30
 Identities = 76/168 (45%), Positives = 85/168 (50%), Gaps = 3/168 (1%)

Query: 57  SPLPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXX 116
           SPL G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG       
Sbjct: 33  SPLSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLV 92

Query: 117 XXXXXLTFAELS---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVA 173
                L FA L+                                        +QP  VVA
Sbjct: 93  IALQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVA 152

Query: 174 GWIVALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            W+  L A++V A PRPWQGP+AVLVA+    AL AHCV RFGG+TGD
Sbjct: 153 AWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGD 200


>tr|B1MNY3|B1MNY3_MYCA9 Tax_Id=561007 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Mycobacterium abscessus]
          Length = 252

 Score =  128 bits (321), Expect = 7e-28
 Identities = 87/228 (38%), Positives = 100/228 (43%), Gaps = 9/228 (3%)

Query: 1   MIRSLAGAFAFGTVLPVRAS-AGVGRG-ALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           ++R + GAF F TV PV A  AG   G  L ALP                        +P
Sbjct: 7   ILRPVGGAFEFATVAPVPARLAGTLSGPVLGALPVVGAALGVLAAFVAWVMHFAYM--AP 64

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           + G          TRGLHIDG  DT DGLGCYGPPERAL VMRDGSAGPFG         
Sbjct: 65  IAGLAAVAATILATRGLHIDGLSDTADGLGCYGPPERALTVMRDGSAGPFGVVVLIICLL 124

Query: 119 XXXLTFAELS----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAG 174
              L+F  L+                                         SQP W+   
Sbjct: 125 AQALSFGVLASRQEWLAVALAITVGRISAVVACRRGVPGAAASGFGTRVAGSQPLWLAGM 184

Query: 175 WIVALAALAVFACP-RPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           W+ A  A+ + A   RPWQGP+ V VA+     LV HCVRRFGGITGD
Sbjct: 185 WVAAAMAVGLLAQTWRPWQGPVVVAVALIAGALLVRHCVRRFGGITGD 232


>tr|D5PP99|D5PP99_COREQ Tax_Id=525370 (cobS)SubName:
           Full=Cobalamin-5-phosphate synthase;
           EC=2.-.-.-;[Rhodococcus equi ATCC 33707]
          Length = 253

 Score =  113 bits (283), Expect = 2e-23
 Identities = 77/229 (33%), Positives = 95/229 (41%), Gaps = 10/229 (4%)

Query: 2   IRSLAGAFAFGTVLPVRASAGVGRG----ALTALPXXXXXXXXXXXXXXXXXXXXXXXXS 57
           +  L+ A ++ TVLPVR    +GR     A+ A P                        +
Sbjct: 5   VAGLSTALSWLTVLPVRGPREIGRAEGRAAIGAAPVVGALLGAGAAAVLWVLVWAGLDPA 64

Query: 58  PLPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXX 117
            L G          TRG+H+DG  DT DGLGCYGPPERA  VMR G AGPFG        
Sbjct: 65  -LAGLLTVGALAVSTRGMHVDGLADTADGLGCYGPPERAREVMRSGGAGPFGVAALIVTI 123

Query: 118 XXXXLTFAEL----SXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVA 173
               L F  L    +                                     SQP W  A
Sbjct: 124 GVQALAFGALGAGGAWIAVAGAVATGRVSAVFACRRGIPASSPSGFGALVADSQPAWTAA 183

Query: 174 GWIVALAALAVFACP-RPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            W  A A  A++A P R WQGPL ++VA+  ++ LV HCVRRF G+ GD
Sbjct: 184 VWGAAAAVAALWAVPDRWWQGPLVIVVALTGAILLVRHCVRRFAGVNGD 232


>tr|D5P724|D5P724_9MYCO Tax_Id=525368 (cobS)SubName:
           Full=Adenosylcobinamide-GDP ribazoletransferase;
           EC=2.-.-.-; Flags: Fragment;[Mycobacterium
           parascrofulaceum ATCC BAA-614]
          Length = 141

 Score =  110 bits (274), Expect = 2e-22
 Identities = 68/133 (51%), Positives = 70/133 (52%), Gaps = 6/133 (4%)

Query: 1   MIRSLAGAFAFGTVLPVRAS--AGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXX-- 56
           MIRSLA AFAFGTVLPV  S  A +GRGA+TALP                          
Sbjct: 1   MIRSLATAFAFGTVLPVPGSRNAPMGRGAMTALPVVGAALGALAAAVVWGGAHVFGPPGS 60

Query: 57  --SPLPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXX 114
             S LPG          TRGLHIDG  DT DGLGCYGPPERALAVMRDGS GPFG     
Sbjct: 61  ISSALPGLLAVAALLAATRGLHIDGVADTADGLGCYGPPERALAVMRDGSTGPFGAAAVV 120

Query: 115 XXXXXXXLTFAEL 127
                  L FA L
Sbjct: 121 LVIALQGLAFAAL 133


>tr|Q0SHL3|Q0SHL3_RHOSR Tax_Id=101510 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Rhodococcus sp.]
          Length = 246

 Score =  107 bits (267), Expect = 1e-21
 Identities = 75/222 (33%), Positives = 89/222 (40%), Gaps = 9/222 (4%)

Query: 8   AFAFGTVLPVRASAGV----GRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSPLPGXX 63
           AF++ TVLP+R    V    GR A+ A P                        + L G  
Sbjct: 7   AFSWLTVLPLRGPDSVDRVSGRRAIRAAPVTGIALGVLAAGLLWALVSAGLDPA-LAGLM 65

Query: 64  XXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLT 123
                   TRG+HIDG  DTVDGLGCYGPPERA AVM  G AGPFG            L 
Sbjct: 66  TVGAHALATRGMHIDGLSDTVDGLGCYGPPERARAVMHSGGAGPFGVCALVICLGAQGLA 125

Query: 124 FAELS----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVAL 179
           F  L+                                         +Q  W    W V L
Sbjct: 126 FGSLAAAGQFACAAVAVAAGRVAVVFACQRGIPASSTEGFGALVAETQSPWTGIAWTVPL 185

Query: 180 AALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            A A +     WQGP+ V+VA+  +  LVAHCVRRF G+ GD
Sbjct: 186 LAAAAWCTLPWWQGPVVVVVALTLTALLVAHCVRRFAGLNGD 227


>tr|D5XUX2|D5XUX2_MYCTU Tax_Id=515617 SubName: Full=Cobalamin
           5-phosphate synthase cobS;[Mycobacterium tuberculosis
           T92]
          Length = 225

 Score =  107 bits (267), Expect = 1e-21
 Identities = 62/130 (47%), Positives = 68/130 (52%), Gaps = 2/130 (1%)

Query: 1   MIRSLAGAFAFGTVLPVRASAG--VGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSP 58
           M+RSLA AFAF TV+P   SA   +GRG +TALP                        SP
Sbjct: 1   MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSP 60

Query: 59  LPGXXXXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXX 118
           L G          TRGLHIDG  DT DGLGCYGPP+RALAVMRDGS GPFG         
Sbjct: 61  LSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIA 120

Query: 119 XXXLTFAELS 128
              L FA L+
Sbjct: 121 LQGLAFATLT 130


>tr|C1A133|C1A133_RHOE4 Tax_Id=234621 (cobV)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Rhodococcus erythropolis]
          Length = 255

 Score =  105 bits (262), Expect = 5e-21
 Identities = 73/225 (32%), Positives = 88/225 (39%), Gaps = 12/225 (5%)

Query: 8   AFAFGTVLPVRASAGV----GRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSPLPGXX 63
           AF++ TVLPVR  + +    GR A+ A P                          L G  
Sbjct: 11  AFSWLTVLPVRGPSDIDRTAGRRAIAAAPLTGIALGIAATFLLWGTTSIGLNPY-LAGLL 69

Query: 64  XXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLT 123
                   TRG+H+DG  D+VDGLGCYGPPERA  VM  G AGPFG            ++
Sbjct: 70  TVGALALATRGMHVDGLADSVDGLGCYGPPERAREVMHSGGAGPFGVAALFIFLGLQSVS 129

Query: 124 FAELS-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWI 176
           F  L+                                            SQP W    W 
Sbjct: 130 FGVLAVADSPTQWIAVLVSVAAGRVAVVFACRRGILASSPSGFGALVADSQPLWAAIVWS 189

Query: 177 VALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           V L A + FA  R W GPL    A+  S+  V HCVRRFGG+ GD
Sbjct: 190 VPLIATSAFATDRWWLGPLVTASALVISVLCVRHCVRRFGGLNGD 234


>tr|C6W9E6|C6W9E6_ACTMD Tax_Id=446462 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Actinosynnema mirum]
          Length = 237

 Score =  105 bits (261), Expect = 6e-21
 Identities = 75/217 (34%), Positives = 86/217 (39%), Gaps = 6/217 (2%)

Query: 8   AFAFGTVLPVRAS---AGVGRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSPLPGXXX 64
           A ++ TVLPVR       V R A+TA P                          L G   
Sbjct: 4   ALSWLTVLPVRVDDVDRRVARRAITAAPLVGVLLGVVAAVVLLGLSALGAPPL-LAGLLV 62

Query: 65  XXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTF 124
                  TRG+H+DG  DT DGLGCYGPPERALAVM+DG AGPFG            +  
Sbjct: 63  VGGLGLATRGMHLDGLADTADGLGCYGPPERALAVMKDGGAGPFGVVTLIVVLGAEAVAL 122

Query: 125 AELSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVALAALAV 184
             +S                                     SQ   VV  W  ALA    
Sbjct: 123 GGVSWGAVVLALTAGRAAFVLCCARGVPAARPEGLGALVAGSQSAGVVVAWWSALAVAG- 181

Query: 185 FACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            A   PW+GPL V +A     ALV H  RRFGG+TGD
Sbjct: 182 -ALVDPWRGPLGVALAAAVVFALVGHTRRRFGGVTGD 217


>tr|C1AUB2|C1AUB2_RHOOB Tax_Id=632772 (cobV)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Rhodococcus opacus]
          Length = 246

 Score =  104 bits (259), Expect = 1e-20
 Identities = 73/222 (32%), Positives = 87/222 (39%), Gaps = 9/222 (4%)

Query: 8   AFAFGTVLPVRASAGV----GRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSPLPGXX 63
           AF++ TVLP+R    V    GR A+ A P                        + L G  
Sbjct: 7   AFSWLTVLPLRGPDSVDRAAGRRAIRAAPVTGIALGALAAGLLWGLVSAGLDPA-LAGLV 65

Query: 64  XXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLT 123
                   TRG+H+DG  DTVDGLGCYGPPERA AVM  G AGPFG            L 
Sbjct: 66  AVGAHALATRGMHVDGLSDTVDGLGCYGPPERARAVMHSGGAGPFGVCALVICLGAQGLA 125

Query: 124 FAELS----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVAL 179
           F  L+                                         +Q  W    W V L
Sbjct: 126 FGSLAAAGQFACVAVAMAAGRVAVVFACRRGIPASSTEGFGALVAETQSPWSGLAWTVPL 185

Query: 180 AALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
            A A +     WQGP+ V  A+  +  LVAHCVRRF G+ GD
Sbjct: 186 LAAAAWCTSPWWQGPVVVTAALTLTALLVAHCVRRFAGMNGD 227


>tr|C3JJB0|C3JJB0_RHOER Tax_Id=596309 (cobS)SubName:
           Full=Cobalamin-5-phosphate synthase;
           EC=2.-.-.-;[Rhodococcus erythropolis SK121]
          Length = 255

 Score =  103 bits (257), Expect = 2e-20
 Identities = 73/225 (32%), Positives = 88/225 (39%), Gaps = 12/225 (5%)

Query: 8   AFAFGTVLPVRASAGV----GRGALTALPXXXXXXXXXXXXXXXXXXXXXXXXSPLPGXX 63
           AF++ TVLPVR  + +    GR A+ A P                          L G  
Sbjct: 11  AFSWLTVLPVRDPSDIDRTAGRRAIAAAPLTGIALGIAATFLLWGTTSIGLNPY-LAGLL 69

Query: 64  XXXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLT 123
                   TRG+H+DG  D+VDGLGCYGPPERA  VM  G AGPFG            ++
Sbjct: 70  TVGALALGTRGMHVDGLADSVDGLGCYGPPERAREVMHSGGAGPFGVAALFIFLGLQSVS 129

Query: 124 FAELS-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWI 176
           F  L+                                            SQP W    W 
Sbjct: 130 FGVLAVADSPTQWIAVLVSVAAGRVAVVFACRRGILASGPSGFGALVADSQPLWAAIVWS 189

Query: 177 VALAALAVFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           V L A + FA  R W GPL    A+  S+  V HCVRRFGG+ GD
Sbjct: 190 VPLIAASGFATDRWWLGPLVTASALVISVLCVRHCVRRFGGLNGD 234


>tr|A4FA93|A4FA93_SACEN Tax_Id=405948 (cobS)SubName: Full=Putative
           cobalamin 5'-phosphate synthase;
           EC=2.7.8.26;[Saccharopolyspora erythraea]
          Length = 244

 Score = 99.8 bits (247), Expect = 3e-19
 Identities = 60/154 (38%), Positives = 68/154 (44%), Gaps = 6/154 (3%)

Query: 72  TRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTFAELS--- 128
           TRG+H+DG  DTVDGLGCYGPPERALAVMRDG AGPF             ++  EL+   
Sbjct: 73  TRGMHVDGLADTVDGLGCYGPPERALAVMRDGGAGPFAVVALVLVLGVQAVSLGELAAAG 132

Query: 129 -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVALAALAVFAC 187
                                                 SQP W VA W + L  L     
Sbjct: 133 DWATVVVACAAGRAGFALCCRTGVPAARPEGMGALVAGSQPVWAVAVWWLLL--LVAAGI 190

Query: 188 PRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
              W GP+AV  A+   L    H  RRFGGITGD
Sbjct: 191 SHWWTGPVAVAAALAALLVFTHHVRRRFGGITGD 224


>tr|Q5YZ46|Q5YZ46_NOCFA Tax_Id=37329 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Nocardia farcinica]
          Length = 259

 Score = 93.6 bits (231), Expect = 2e-17
 Identities = 71/222 (31%), Positives = 83/222 (37%), Gaps = 9/222 (4%)

Query: 8   AFAFGTVLPVRASAGVGRGALT---ALPXXXXXXXXXXXXXXXXXXXXXXXXSPLPGXXX 64
           AF++ TVLPVR    V R       AL                         + L     
Sbjct: 17  AFSWLTVLPVRGPEEVDRAGAARAIALAPVVGVVLGAAAAGLTWSLVAAGLSTGLAALLA 76

Query: 65  XXXXXXXTRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTF 124
                   RG+H+DG  DT DGLG YGPPERA  +M+ G  GPFG            L F
Sbjct: 77  VGALAVAARGMHLDGLADTADGLGSYGPPERARQIMKGGDVGPFGVAAIVFAVGVPALAF 136

Query: 125 ----AELSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVALA 180
               AE                                         P   V  W +  A
Sbjct: 137 GTAAAEGRWLAIGLAVALGRVVVVLACRRAPAAPGTGFGSLVAATQHPATGVV-WTILAA 195

Query: 181 ALAVFACP-RPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
             AVFA P R W GPL VLVA+  +L LV HCVRRF G++GD
Sbjct: 196 VCAVFAVPGRAWLGPLVVLVAVAAALLLVRHCVRRFEGLSGD 237


>tr|D5UXQ7|D5UXQ7_TSUPA Tax_Id=521096 SubName:
           Full=Cobalamin-5-phosphate synthase CobS;[Tsukamurella
           paurometabola DSM 20162]
          Length = 250

 Score = 92.8 bits (229), Expect = 3e-17
 Identities = 54/155 (34%), Positives = 70/155 (45%), Gaps = 5/155 (3%)

Query: 72  TRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTFAELS--- 128
           TRG+H+DGF D VDGLG YGPP+RA  +MR GS GPFG                +L+   
Sbjct: 76  TRGMHVDGFADCVDGLGSYGPPDRAREIMRQGSVGPFGAAALALVVLIDAAAIGDLADRA 135

Query: 129 -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWIVALAALAVFAC 187
                                                 +Q     A W+   A  A++A 
Sbjct: 136 QWIAIGVAIGAARVAAVIGCRRGWCAANPDGFGALTAGTQGGAAQAFWMFVAAIAAIWAV 195

Query: 188 PR-PWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           P  PWQGPLAV+ A+  +   + HCVRRFGG++GD
Sbjct: 196 PDVPWQGPLAVVAAMLAAALAMRHCVRRFGGVSGD 230


>tr|D1SDN6|D1SDN6_9ACTO Tax_Id=644283 SubName: Full=Cobalamin
           5'-phosphate synthase;[Micromonospora aurantiaca ATCC
           27029]
          Length = 257

 Score = 77.8 bits (190), Expect = 1e-12
 Identities = 56/163 (34%), Positives = 68/163 (41%), Gaps = 18/163 (11%)

Query: 72  TRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTFAELSXXX 131
           TRGLH+DG  DTVD LG Y     AL +M+    GPFG               AEL+   
Sbjct: 79  TRGLHLDGLADTVDALGSYRRGPAALEIMKQPDVGPFGVVALVVVLLLQSAVLAELAGRD 138

Query: 132 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVA------GW---IVALAAL 182
                                             ++P  + A      GW    V   A+
Sbjct: 139 ALAAFAAVVAATAAGRLAVGLACRRGVPA-----ARPEGLGALVAGTVGWGAPAVGAVAV 193

Query: 183 AVFACP----RPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           A+ A P    RPWQGPLAVL A+  +  L+ H VRRFGGITGD
Sbjct: 194 ALAAVPAVADRPWQGPLAVLAALAVAAGLLRHLVRRFGGITGD 236


>tr|A4XA08|A4XA08_SALTO Tax_Id=369723 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-;[Salinispora tropica]
          Length = 257

 Score = 76.6 bits (187), Expect = 2e-12
 Identities = 55/160 (34%), Positives = 67/160 (41%), Gaps = 12/160 (7%)

Query: 72  TRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTFAELSXXX 131
           TRGLH+DG  DTVD LG Y     AL +M+    GPFG               AEL+   
Sbjct: 79  TRGLHLDGLADTVDALGSYRRGPAALEIMKKPDVGPFGVAALVVILLLQAAVLAELAEWS 138

Query: 132 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWI---------VALAAL 182
                                                  +VAG +          A+A L
Sbjct: 139 TSTMLTAVVTATAAGRLGVTVACWRGLPAARPDGLGA--LVAGTVGPGTLAAGTAAVALL 196

Query: 183 AVFACP-RPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           A+ A P RPWQGPLAV VA+  ++ L+ H VRR GGITGD
Sbjct: 197 ALAAVPDRPWQGPLAVAVALAAAVGLLRHVVRRLGGITGD 236


>tr|C4RMI3|C4RMI3_9ACTO Tax_Id=219305 SubName:
           Full=Cobalamin-5-phosphate synthase cobS;[Micromonospora
           sp. ATCC 39149]
          Length = 278

 Score = 75.5 bits (184), Expect = 5e-12
 Identities = 54/160 (33%), Positives = 67/160 (41%), Gaps = 12/160 (7%)

Query: 72  TRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTFAELSXXX 131
           TRGLH+DG  DTVD LG Y     AL +M+    GPFG               AEL+   
Sbjct: 100 TRGLHLDGLADTVDALGSYRRGAAALEIMKKPDVGPFGVAALVVVLLVQAAALAELASRS 159

Query: 132 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWI---------VALAAL 182
                                                  +VAG +          A+A +
Sbjct: 160 GPAALAAMVAATAAGRLGVTLACRRGVPAARPDGLGA--LVAGTVGPVAAVVGTAAVALV 217

Query: 183 AVFACP-RPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           AV A P RPWQGP+AVL A+  ++ L+ H VRR GGITGD
Sbjct: 218 AVAAVPGRPWQGPVAVLAALAVAVLLLRHAVRRLGGITGD 257


>tr|D0LAY2|D0LAY2_GORB4 Tax_Id=526226 (cobS)RecName: Full=Cobalamin
           synthase; EC=2.-.-.-; Flags: Precursor;[Gordonia
           bronchialis]
          Length = 261

 Score = 73.2 bits (178), Expect = 3e-11
 Identities = 54/163 (33%), Positives = 60/163 (36%), Gaps = 13/163 (7%)

Query: 72  TRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTFAEL---S 128
           TRG+H+DG  DT DGLGCYGPP R   VMR G+ GPFG            + F  L   S
Sbjct: 80  TRGMHLDGLADTADGLGCYGPPSRVTEVMRSGTVGPFGVATLVLVLGIQGVGFGALFDQS 139

Query: 129 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGW-IVALAALA---- 183
                                                   R  +  W  +ALAA A    
Sbjct: 140 RWYDAAFAVALGRVGVLVAARRGLAPAHPDGFGALVAGTQRNALVVWAALALAAAAVCGF 199

Query: 184 -----VFACPRPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
                VF  P      L VLV         AHC RR GGITGD
Sbjct: 200 DVSTGVFDLPAAVTAMLVVLVVAVVVWLFTAHCARRMGGITGD 242


>tr|A8LYE0|A8LYE0_SALAI Tax_Id=391037 SubName:
           Full=Cobalamin-5-phosphate synthase CobS;[Salinispora
           arenicola]
          Length = 257

 Score = 72.8 bits (177), Expect = 3e-11
 Identities = 54/160 (33%), Positives = 65/160 (40%), Gaps = 12/160 (7%)

Query: 72  TRGLHIDGFCDTVDGLGCYGPPERALAVMRDGSAGPFGXXXXXXXXXXXXLTFAELSXXX 131
           TRGLH+DG  DTVD LG Y     AL +M+    GPFG               AEL+   
Sbjct: 79  TRGLHLDGLADTVDALGSYRRGPAALEIMKKPDVGPFGVTALVVVLLVQAAVLAELAERS 138

Query: 132 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQPRWVVAGWI---------VALAAL 182
                                                  +VAG +         VA+A L
Sbjct: 139 ALATLAAVVTATATGRLGVGVACRRGLPAARPDGLGA--LVAGTVGPPALAAGTVAVALL 196

Query: 183 AVFACP-RPWQGPLAVLVAIGCSLALVAHCVRRFGGITGD 221
           A  A P RPWQGPL V  A+  ++ L+ H VRR GGITGD
Sbjct: 197 AFAAVPDRPWQGPLVVAAALATAVWLLRHVVRRLGGITGD 236


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.326    0.143    0.471 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 1,128,640,977
Number of extensions: 29160887
Number of successful extensions: 90840
Number of sequences better than 10.0: 552
Number of HSP's gapped: 90939
Number of HSP's successfully gapped: 610
Length of query: 241
Length of database: 4,236,830,644
Length adjustment: 134
Effective length of query: 107
Effective length of database: 2,560,776,868
Effective search space: 274003124876
Effective search space used: 274003124876
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 79 (35.0 bits)