BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_4512 (997 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|A0R0U6|A0R0U6_MYCS2 Tax_Id=246196 SubName: Full=Polyketide sy... 1607 0.0 tr|Q1B6B0|Q1B6B0_MYCSS Tax_Id=164756 SubName: Full=Acyl transfer... 683 0.0 tr|A1UIR6|A1UIR6_MYCSK Tax_Id=189918 SubName: Full=Acyl transfer... 683 0.0 tr|A3Q279|A3Q279_MYCSJ Tax_Id=164757 SubName: Full=Acyl transfer... 679 0.0 tr|A1TBS7|A1TBS7_MYCVP Tax_Id=350058 SubName: Full=Acyl transfer... 679 0.0 tr|Q7D790|Q7D790_MYCTU Tax_Id=1773 SubName: Full=Polyketide synt... 637 e-180 tr|A2VKA7|A2VKA7_MYCTU Tax_Id=348776 SubName: Full=Polyketide sy... 637 e-180 tr|Q7TYQ6|Q7TYQ6_MYCBO Tax_Id=1765 (mbtD)SubName: Full=POLYKETID... 637 e-180 tr|P71719|P71719_MYCTU Tax_Id=1773 (mbtD)SubName: Full=POLYKETID... 637 e-180 tr|C6DNA3|C6DNA3_MYCTK Tax_Id=478434 SubName: Full=Polyketide sy... 637 e-180 tr|C1AQU4|C1AQU4_MYCBT Tax_Id=561275 (mbtD)SubName: Full=Polyket... 637 e-180 tr|A5WPZ6|A5WPZ6_MYCTF Tax_Id=336982 SubName: Full=Polyketide sy... 637 e-180 tr|A5U574|A5U574_MYCTA Tax_Id=419947 (mbtD)SubName: Full=Putativ... 637 e-180 tr|A1KL71|A1KL71_MYCBP Tax_Id=410289 (mbtD)SubName: Full=Polyket... 637 e-180 tr|D6G568|D6G568_MYCTU Tax_Id=478435 SubName: Full=Polyketide sy... 637 e-180 tr|D6FXX7|D6FXX7_MYCTU Tax_Id=611304 SubName: Full=Polyketide sy... 637 e-180 tr|D6FIU1|D6FIU1_MYCTU Tax_Id=611303 SubName: Full=Polyketide sy... 637 e-180 tr|D6F6H7|D6F6H7_MYCTU Tax_Id=611302 SubName: Full=Polyketide sy... 637 e-180 tr|D5ZGV6|D5ZGV6_MYCTU Tax_Id=537210 SubName: Full=Polyketide sy... 637 e-180 tr|D5YHK7|D5YHK7_MYCTU Tax_Id=520140 SubName: Full=Polyketide sy... 637 e-180 tr|D5Y668|D5Y668_MYCTU Tax_Id=520141 SubName: Full=Polyketide sy... 637 e-180 tr|D5XVF1|D5XVF1_MYCTU Tax_Id=515617 SubName: Full=Polyketide sy... 637 e-180 tr|A4KJD1|A4KJD1_MYCTU Tax_Id=395095 SubName: Full=Polyketide sy... 637 e-180 tr|A4T2C9|A4T2C9_MYCGI Tax_Id=350054 SubName: Full=Acyl transfer... 623 e-176 tr|Q73XY4|Q73XY4_MYCPA Tax_Id=1770 (mbtD)SubName: Full=MbtD;[Myc... 617 e-174 tr|A0QE93|A0QE93_MYCA1 Tax_Id=243243 SubName: Full=MbtD protein;... 613 e-173 tr|D5PHG3|D5PHG3_9MYCO Tax_Id=525368 (mbtD2)SubName: Full=Mycoba... 588 e-165 tr|D5Z5Q4|D5Z5Q4_MYCTU Tax_Id=537209 SubName: Full=Polyketide sy... 511 e-142 tr|Q83ZY9|Q83ZY9_MYCSM Tax_Id=1772 (mbtD)SubName: Full=Polyketid... 470 e-130 tr|D0L269|D0L269_GORB4 Tax_Id=526226 SubName: Full=Acyl transfer... 305 2e-80 tr|B2HM91|B2HM91_MYCMM Tax_Id=216594 (mbtD)SubName: Full=Polyket... 302 1e-79 tr|Q5Z1T1|Q5Z1T1_NOCFA Tax_Id=37329 (nbtC)SubName: Full=Putative... 302 2e-79 tr|A0PTV2|A0PTV2_MYCUA Tax_Id=362242 (mbtD)SubName: Full=Polyket... 291 4e-76 tr|B1MPE9|B1MPE9_MYCA9 Tax_Id=561007 SubName: Full=Putative poly... 286 1e-74 tr|Q9F828|Q9F828_9ACTO Tax_Id=136926 (megAIII)SubName: Full=Mega... 232 2e-58 tr|Q83X69|Q83X69_STRRO Tax_Id=1928 (lkmAI)SubName: Full=Lankamyc... 230 7e-58 tr|A4F7P1|A4F7P1_SACEN Tax_Id=405948 (eryAIII)SubName: Full=EryA... 224 5e-56 tr|Q5UNP4|Q5UNP4_SACER Tax_Id=1836 (eryAIII)SubName: Full=EryAII... 224 5e-56 tr|D3U9Y7|D3U9Y7_9ACTO Tax_Id=67297 (sfaG)SubName: Full=Type I p... 219 1e-54 tr|D5UZ35|D5UZ35_TSUPA Tax_Id=521096 SubName: Full=Acyl transfer... 218 4e-54 sp|Q03133|ERYA3_SACER Tax_Id=1836 (eryA)RecName: Full=Erythronol... 214 7e-53 tr|Q0QMN7|Q0QMN7_9ACTO Tax_Id=358765 SubName: Full=Polyketide sy... 205 3e-50 tr|A1YBQ3|A1YBQ3_SORCE Tax_Id=56 (ambB)SubName: Full=AmbB;[Soran... 203 1e-49 tr|D0L275|D0L275_GORB4 Tax_Id=526226 SubName: Full=Acyl transfer... 199 2e-48 tr|Q331Q3|Q331Q3_9ACTO Tax_Id=201500 (gerSIV)SubName: Full=Putat... 198 3e-48 >tr|A0R0U6|A0R0U6_MYCS2 Tax_Id=246196 SubName: Full=Polyketide synthetase mbtd;[Mycobacterium smegmatis] Length = 997 Score = 1607 bits (4161), Expect = 0.0 Identities = 834/997 (83%), Positives = 834/997 (83%) Query: 1 MMTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXX 60 MMTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAY Sbjct: 1 MMTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYTLLRTRRLRRHR 60 Query: 61 AVIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY 120 AVIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY Sbjct: 61 AVIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY 120 Query: 121 RLDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 RLDDYRAEVDRC SPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV Sbjct: 121 RLDDYRAEVDRCAAAFEAAGAASPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP Sbjct: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 EQAAEVIAETPGWLEL GE FAKEIEMWFPAHTT Sbjct: 241 EQAAEVIAETPGWLELSVVNSPSSVAVSGETGAVAAAVRTVAARGAFAKEIEMWFPAHTT 300 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQ Sbjct: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQAVAR 360 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADA 420 IFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADA Sbjct: 361 AARRGARIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADA 420 Query: 421 GYRWRDQLGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHH 480 GYRWRDQLGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHH Sbjct: 421 GYRWRDQLGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHH 480 Query: 481 RIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRR 540 RIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRR Sbjct: 481 RIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRR 540 Query: 541 IDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFR 600 IDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFR Sbjct: 541 IDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFR 600 Query: 601 QLDVPMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGV 660 QLDVPMGLD DLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGV Sbjct: 601 QLDVPMGLDTEAAVTAVAAMVTGTTDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGV 660 Query: 661 LDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDELPLGVEIVAPRCDLTD 720 LDDVVITGGTGAVGLQF SRNGIEGNRVDELPLGVEIVAPRCDLTD Sbjct: 661 LDDVVITGGTGAVGLQFARRLAALGARRIVLLSRNGIEGNRVDELPLGVEIVAPRCDLTD 720 Query: 721 IPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVR 780 IPRVRDVAAEFGGQGASLIVH IENVLAAWPVR Sbjct: 721 IPRVRDVAAEFGGQGASLIVHAAATATIAAGSALTGAAAQATFTAKLAGIENVLAAWPVR 780 Query: 781 PDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDA 840 PDARILLCSSVSGLW NRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDA Sbjct: 781 PDARILLCSSVSGLWGGHGHAAYAAANRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDA 840 Query: 841 DEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREATHA 900 DEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREATHA Sbjct: 841 DEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREATHA 900 Query: 901 AQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 960 AQHRDAGPPADAEHHDTGAAVRIALAAVLK Sbjct: 901 AQHRDAGPPADAEHHDTGAAVRIALAAVLKLADTTGLDLDASLLDLGVDSLLALDLRKKL 960 Query: 961 XXTTGRSVPLATLLGGVTATELIEHLERPEKETFSRD 997 TTGRSVPLATLLGGVTATELIEHLERPEKETFSRD Sbjct: 961 KKTTGRSVPLATLLGGVTATELIEHLERPEKETFSRD 997 >tr|Q1B6B0|Q1B6B0_MYCSS Tax_Id=164756 SubName: Full=Acyl transferase region;[Mycobacterium sp.] Length = 978 Score = 683 bits (1762), Expect = 0.0 Identities = 428/1000 (42%), Positives = 531/1000 (53%), Gaps = 41/1000 (4%) Query: 9 DHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGL 68 D R+PV+LSAHA DL+A DA A+L YLD + +DVA V+RAG Sbjct: 9 DGRIPVLLSAHAGDLVAEDARAVLGYLDHDPAASVADVAGHLLTTRRVRRHRTVVRAGDR 68 Query: 69 DELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR-LDDYRA 127 DEL GLRA+A G +HPLV R+A GS R+AFVFPGQG+QWPSMG +AY L YRA Sbjct: 69 DELADGLRAVAHGAEHPLVARSAE---GSPSRIAFVFPGQGTQWPSMGTQAYEELPQYRA 125 Query: 128 EVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVV 187 D C SP+ YL + FS+ +I+GAQF H VALA VWRS+GV+ Sbjct: 126 AADACAEAFTAAGAASPMRYLTTPG----TAEGFSEAEIEGAQFTHAVALAHVWRSYGVL 181 Query: 188 PDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVI 247 PDITVGHSLGEIGAAY+AGAITL +AVA+VIARA V+DRL+G + VAVLG+ PE A +VI Sbjct: 182 PDITVGHSLGEIGAAYLAGAITLADAVAVVIARAEVVDRLSGDHAVAVLGVDPETAQQVI 241 Query: 248 AETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRA 307 A TPGWLEL G+ FA+EI + FP HT+ L+ +R Sbjct: 242 AATPGWLELSVVNAATSVAVSGDRRAVSAAVARVREQGRFAREITVGFPVHTSILEPLRD 301 Query: 308 DLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXX 367 D LP FA++PVQFIG AT DVV G F DYWY NLRT VRFD+ Sbjct: 302 DFVKQLPQAVFADSPVQFIGGATGDVVPAGAMFGDYWYANLRTMVRFDRAFESARRCGAT 361 Query: 368 IFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQ 427 FVELSAHP LLF MG+LL T LVGSGRRD P+ E L+DN+ A++D G+ WRD Sbjct: 362 TFVELSAHPQLLFAMGDLLGDTT-ATLVGSGRRDTPITEALSDNLAVAAVSDPGHGWRDA 420 Query: 428 LGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHH---RIAV 484 + L FP APMRA LWAQP+PL +TVA E W + S H + V Sbjct: 421 VERTAHRLRGFPNAPMRATPLWAQPEPLSETADITVAQEVWQPIDDVTPSAHTAPVTVTV 480 Query: 485 VGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRRIDEG 544 + L + LR A + G+ + P AD ++VVAP D A + + G Sbjct: 481 LELGATGPFGERLRTAVDAHPGMALGTPDTADVMVVVAPQPGGADAKTAVTTVTDLVGSG 540 Query: 545 LLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDV 604 LRYP RD+WLVT E V +L AA+AAMHRS+ E+P+ F LD+ Sbjct: 541 ALRYPASAGPRCRDIWLVTAGAERVRAGEPQALS-AAAIAAMHRSLGLENPELGFHHLDL 599 Query: 605 PMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPWP--TGVLD 662 P D +LA+R G G L+RR + DA A A W +G+LD Sbjct: 600 P--ADPTIDTAVVDTLLTGAGELAIR----GGDGPVLYRRTVADAPVAPA-WSLGSGILD 652 Query: 663 DVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL--PLGVEIVAPRCDLTD 720 +VVITGG G +GL + SR ++ + EL P G E+V+ CDLTD Sbjct: 653 EVVITGGAGRIGLHYARHLAERGARRIVLLSRRAVDPAVLAELTAPRGTEVVSVPCDLTD 712 Query: 721 IPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVR 780 +R A +F G GASL++H + ++ WP+ Sbjct: 713 RESIR-TATDFAGIGASLVIHAAGAATFAEGDRLDAAAAVNTLGAKVTGLAHLADLWPLH 771 Query: 781 PDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLW---PGAGI 837 PDARI+LCSSVSGLW NR+LD MA RLR++G RC +VRWGLW G GI Sbjct: 772 PDARIVLCSSVSGLWGGHGHAVYSAANRMLDAMAGRLRADGHRCVSVRWGLWRSDSGEGI 831 Query: 838 IDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREA 897 + A E R+ERSGLR MAP A++ +L D DPLVFSAD R+ +F A T R+ Sbjct: 832 VGAAETARIERSGLRPMAPLPAIEASLCDHTVDPLVFSADPHRMQMF---SAATEPVRDP 888 Query: 898 THAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXXXXXXXXXXXXXXXXXXXXXXX 957 A A DT AVR LAAVLK Sbjct: 889 QTA--------ETTAAPVDTADAVRAELAAVLKITDPGGIDLDASLFDLGVDSLLALDLG 940 Query: 958 XXXXXTTGRSVPLATLLGGVTATELIEHLERPEKETFSRD 997 GR+VPLATLLGGVT EL+ L+ EK RD Sbjct: 941 KRFRRVLGRTVPLATLLGGVTGAELVAELD--EKVEIPRD 978 >tr|A1UIR6|A1UIR6_MYCSK Tax_Id=189918 SubName: Full=Acyl transferase domain protein;[Mycobacterium sp.] Length = 978 Score = 683 bits (1762), Expect = 0.0 Identities = 428/1000 (42%), Positives = 531/1000 (53%), Gaps = 41/1000 (4%) Query: 9 DHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGL 68 D R+PV+LSAHA DL+A DA A+L YLD + +DVA V+RAG Sbjct: 9 DGRIPVLLSAHAGDLVAEDARAVLGYLDHDPAASVADVAGHLLTTRRVRRHRTVVRAGDR 68 Query: 69 DELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR-LDDYRA 127 DEL GLRA+A G +HPLV R+A GS R+AFVFPGQG+QWPSMG +AY L YRA Sbjct: 69 DELADGLRAVAHGAEHPLVARSAE---GSPSRIAFVFPGQGTQWPSMGTQAYEELPQYRA 125 Query: 128 EVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVV 187 D C SP+ YL + FS+ +I+GAQF H VALA VWRS+GV+ Sbjct: 126 AADACAEAFTAAGAASPMRYLTTPG----TAEGFSEAEIEGAQFTHAVALAHVWRSYGVL 181 Query: 188 PDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVI 247 PDITVGHSLGEIGAAY+AGAITL +AVA+VIARA V+DRL+G + VAVLG+ PE A +VI Sbjct: 182 PDITVGHSLGEIGAAYLAGAITLADAVAVVIARAEVVDRLSGDHAVAVLGVDPETAQQVI 241 Query: 248 AETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRA 307 A TPGWLEL G+ FA+EI + FP HT+ L+ +R Sbjct: 242 AATPGWLELSVVNAATSVAVSGDRRAVSAAVARVREQGRFAREITVGFPVHTSILEPLRD 301 Query: 308 DLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXX 367 D LP FA++PVQFIG AT DVV G F DYWY NLRT VRFD+ Sbjct: 302 DFVKQLPQAVFADSPVQFIGGATGDVVPAGAMFGDYWYANLRTMVRFDRAFESARRCGAT 361 Query: 368 IFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQ 427 FVELSAHP LLF MG+LL T LVGSGRRD P+ E L+DN+ A++D G+ WRD Sbjct: 362 TFVELSAHPQLLFAMGDLLGDTT-ATLVGSGRRDTPITEALSDNLAVAAVSDPGHGWRDA 420 Query: 428 LGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHH---RIAV 484 + L FP APMRA LWAQP+PL +TVA E W + S H + V Sbjct: 421 VERTAHRLRGFPNAPMRATPLWAQPEPLSETADITVAQEVWQPIDDVTPSAHTAPVTVTV 480 Query: 485 VGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRRIDEG 544 + L + LR A + G+ + P AD ++VVAP D A + + G Sbjct: 481 LELGATGPFGERLRTAVDAHPGMALGTPDTADVMVVVAPQPGGADAKTAVTTVTDLVGSG 540 Query: 545 LLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDV 604 LRYP RD+WLVT E V +L AA+AAMHRS+ E+P+ F LD+ Sbjct: 541 ALRYPASAGPRCRDIWLVTAGAERVRAGEPQALS-AAAIAAMHRSLGLENPELGFHHLDL 599 Query: 605 PMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPWP--TGVLD 662 P D +LA+R G G L+RR + DA A A W +G+LD Sbjct: 600 P--ADPTIDTAVVDTLLTGAGELAIR----GGDGPVLYRRTVADAPVAPA-WSLGSGILD 652 Query: 663 DVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL--PLGVEIVAPRCDLTD 720 +VVITGG G +GL + SR ++ + EL P G E+V+ CDLTD Sbjct: 653 EVVITGGAGRIGLHYARHLAERGARRIVLLSRRAVDPAVLAELTAPRGTEVVSVPCDLTD 712 Query: 721 IPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVR 780 +R A +F G GASL++H + ++ WP+ Sbjct: 713 RESIR-TATDFAGIGASLVIHAAGAATFAEGDRLDAAAAVNTLGAKVTGLAHLADLWPLH 771 Query: 781 PDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLW---PGAGI 837 PDARI+LCSSVSGLW NR+LD MA RLR++G RC +VRWGLW G GI Sbjct: 772 PDARIVLCSSVSGLWGGHGHAVYSAANRMLDAMAGRLRADGHRCVSVRWGLWRSDSGEGI 831 Query: 838 IDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREA 897 + A E R+ERSGLR MAP A++ +L D DPLVFSAD R+ +F A T R+ Sbjct: 832 VGAAETARIERSGLRPMAPLPAIEASLCDHTVDPLVFSADPHRMQMF---SAATEPVRDP 888 Query: 898 THAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXXXXXXXXXXXXXXXXXXXXXXX 957 A A DT AVR LAAVLK Sbjct: 889 QTA--------ETTAAPVDTADAVRAELAAVLKITDPGGIDLDASLFDLGVDSLLALDLG 940 Query: 958 XXXXXTTGRSVPLATLLGGVTATELIEHLERPEKETFSRD 997 GR+VPLATLLGGVT EL+ L+ EK RD Sbjct: 941 KRFRRVLGRTVPLATLLGGVTGAELVAELD--EKVEIPRD 978 >tr|A3Q279|A3Q279_MYCSJ Tax_Id=164757 SubName: Full=Acyl transferase domain protein;[Mycobacterium sp.] Length = 978 Score = 679 bits (1752), Expect = 0.0 Identities = 426/1000 (42%), Positives = 529/1000 (52%), Gaps = 41/1000 (4%) Query: 9 DHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGL 68 D R+PV+LSAHA DL+A DA A+L YLD + +DVA V+RAG Sbjct: 9 DGRIPVLLSAHAGDLVAEDARAVLGYLDHDPAASVADVAGHLLTTRRVRRHRTVVRAGDR 68 Query: 69 DELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR-LDDYRA 127 DEL GLRA+A+G +HPLV +A GS R+AFVFPGQG+QWPSMG +AY L YRA Sbjct: 69 DELADGLRAVAEGAEHPLVACSAE---GSPSRIAFVFPGQGTQWPSMGTQAYEELPQYRA 125 Query: 128 EVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVV 187 D C SP+ YL + +FS+ +I+GAQF H VALA VWRS+GV+ Sbjct: 126 AADACAEAFTAAGAASPMRYLTTPG----TAEEFSEAEIEGAQFTHAVALAHVWRSYGVL 181 Query: 188 PDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVI 247 PDITVGHSLGEIGAAY+AGAITL +AVA+VIARA V+DRL+G + VAVLG+ PE A +VI Sbjct: 182 PDITVGHSLGEIGAAYLAGAITLADAVAVVIARAEVVDRLSGDHAVAVLGVDPETAQQVI 241 Query: 248 AETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRA 307 A TPGWLEL G+ FA+EI + FP HT+ L+ +R Sbjct: 242 AATPGWLELSVVNAATSVAVSGDRRAVSAAVALVREQGRFAREITVGFPVHTSILEPLRD 301 Query: 308 DLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXX 367 D LP FA+TPVQFIG AT DVV G F DYWY NLRT VRFD Sbjct: 302 DFVKQLPQAVFADTPVQFIGGATGDVVPAGAMFGDYWYANLRTMVRFDHAFESARRCGAT 361 Query: 368 IFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQ 427 FVELSAHP LLF MG+LL T LVGSGRRD P+ E L+DN+ A++D G+ WRD Sbjct: 362 TFVELSAHPQLLFAMGDLLGDTT-ATLVGSGRRDTPITEALSDNLAVAAISDPGHGWRDA 420 Query: 428 LGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHH---RIAV 484 + L FP APMRA LWAQP+PL +TVA E W + S H + V Sbjct: 421 VEPTAHRLRGFPNAPMRATPLWAQPEPLSETADITVAQEVWQPIDDVTPSAHTAPVTVTV 480 Query: 485 VGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRRIDEG 544 + L + LR A + G+ + P AD ++VVAP D A + + G Sbjct: 481 LELGATGPFGERLRTAVDAHPGMALGTPDTADVMVVVAPQPGGADAKTAVTTVTDLVGSG 540 Query: 545 LLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDV 604 LRYP RD+WLVT E V +L AA+AAMHRS+ E+P+ F LD+ Sbjct: 541 ALRYPASAGPRCRDIWLVTAGAERVRTGEPQALS-AAAIAAMHRSLGLENPELGFHHLDL 599 Query: 605 PMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPW--PTGVLD 662 P D + A+R G G L+RR + DA A A W +G+LD Sbjct: 600 P--ADPTIDTAVVDTLLTGAGERAIR----GGDGPVLYRRTVADAPVAPA-WSLDSGILD 652 Query: 663 DVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDELPL--GVEIVAPRCDLTD 720 +VVITGG G +GL + SR ++ + EL G E+V+ CDLTD Sbjct: 653 EVVITGGAGRIGLHYARHLAERGARRIVLLSRRAVDPAVLAELTAARGTEVVSVPCDLTD 712 Query: 721 IPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVR 780 +R A +F G GASL++H + ++ WP+ Sbjct: 713 RESIR-TATDFAGIGASLVIHAAGAATFASGDRLDAAAAVNTLGAKVTGLAHLADLWPLH 771 Query: 781 PDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLW---PGAGI 837 PDARI+LCSSVSGLW NR+LD MA RLR++G RC +VRWGLW G GI Sbjct: 772 PDARIVLCSSVSGLWGGHGHAVYSAANRMLDAMAGRLRADGHRCVSVRWGLWRSDSGEGI 831 Query: 838 IDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREA 897 + A E R+ERSGLR MAP A++ +L D DPLVFSAD R+ +F A T R+ Sbjct: 832 VGAAETARIERSGLRPMAPLPAIEASLCDHTVDPLVFSADPHRMQMF---SAATEPVRDP 888 Query: 898 THAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXXXXXXXXXXXXXXXXXXXXXXX 957 A A DT AVR LAAVLK Sbjct: 889 QTA--------ETTAAPVDTADAVRAELAAVLKITDPGGIDLDASLFDLGVDSLLALDLR 940 Query: 958 XXXXXTTGRSVPLATLLGGVTATELIEHLERPEKETFSRD 997 GR+VPLATLLGGVT EL+ L+ EK RD Sbjct: 941 KRFRRVLGRTVPLATLLGGVTGAELVAELD--EKVEIPRD 978 >tr|A1TBS7|A1TBS7_MYCVP Tax_Id=350058 SubName: Full=Acyl transferase domain protein;[Mycobacterium vanbaalenii] Length = 972 Score = 679 bits (1752), Expect = 0.0 Identities = 433/1010 (42%), Positives = 531/1010 (52%), Gaps = 52/1010 (5%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M+ G L D RV V LSAH E L++ A IL +L R + P VA A Sbjct: 1 MSAGRLPDGRVAVPLSAHHEALVSATARDILGHLQ-RNPSEPGQVAAQLVRTRRLRRHRA 59 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 ++RAG DEL AGL+A+AD DHPLV R+A + R AFVFPGQGSQWP MG EAYR Sbjct: 60 IVRAGDRDELAAGLQAVADDRDHPLVARSAGR---AGARTAFVFPGQGSQWPGMGGEAYR 116 Query: 122 L-DDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YRAE DR SPL +L A D SQ +Q AQFVH VALA V Sbjct: 117 LLPVYRAEADRLTEAFLAAGLTSPLPFLTADTDG----EPVSQYDLQAAQFVHSVALAAV 172 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS G+VPD+TVGHSLGE+ AAYVA +TL +AV ++ ARA ++ + G VAVLG+ Sbjct: 173 WRSCGIVPDLTVGHSLGEVAAAYVAETVTLVDAVTVLAARAAAIEAIPGDNGVAVLGVDA 232 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 +AAE+IA T GWLEL GE FAKE+ M FPAHTT Sbjct: 233 TEAAELIAATGGWLELSAVNAQNSVAVSGERSAVAAIAAAARARGRFAKELAMSFPAHTT 292 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 A++ R L LP FA++PVQF+GSAT +V GT+F YWY NLR T+RFDQ Sbjct: 293 AMETQREQLVRRLPTSVFADSPVQFVGSATGQLVRAGTEFGAYWYANLRNTIRFDQAVQT 352 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLE--STRGVVLVGSGRRDEPLPERLADNVITVALA 418 ++VELSAHP+LLF + + +E VLVGSG RDE +P+RL+ N++T A A Sbjct: 353 AIGLGAGVYVELSAHPSLLFAVEDGIERVGAAAAVLVGSGHRDESVPDRLSANIVTAAAA 412 Query: 419 DAGYRWRDQLGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSG 478 D YRW D L L FP APMRAEHLWA+P+PLP GLTV E W Q VS Sbjct: 413 DPAYRWGDLLTGEPEPLFGFPGAPMRAEHLWAEPEPLPVAPGLTVTTETWRQRRPRRVSA 472 Query: 479 H--HRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEE 536 R+AV+ S A++ LR A +R + V A AD +VVAP + D E Sbjct: 473 KVSRRVAVIESGSGTAISRSLRQAIDRRADLSVAGAADADLAIVVAPTFAGADAAGCVNE 532 Query: 537 LGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPD 596 L ID GLL Y D RDVWLVT E+V + A VAA+HR I FEHPD Sbjct: 533 LSGAIDTGLLGYADTFGPRCRDVWLVTVGAENVTAEDPAPDLGQAGVAALHRCIGFEHPD 592 Query: 597 QNFRQLDVPMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPW 656 Q+F LD+P G +LALR D ++ R + D ++ A PW Sbjct: 593 QSFHHLDLPAGATDALGAVDVMVDGAG--ELALRRD------GQVYERTLGDDTSTAPPW 644 Query: 657 P--TGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDELPLGVEIVAP 714 +G LD+VVITGG+GA+GL F SR G +D L G EI+AP Sbjct: 645 DLSSGTLDNVVITGGSGAIGLSFARFLAARGARRIVLLSRRGAGPAPLDNL--GAEIIAP 702 Query: 715 RCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVL 774 CDL D ++ AEF G ASLI+H +E + Sbjct: 703 ACDLRDPRQLAATVAEFAGGPASLIIHAAGTATFANRADITGAALADMAGAKIIGLEALT 762 Query: 775 AAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPG 834 WP+R DARILLCSSV+G+W NR+LDVMA RL ++GR CTAVR+GLW G Sbjct: 763 RTWPIRDDARILLCSSVTGVWGGKGVGGYAAANRMLDVMAARLGADGRNCTAVRFGLWEG 822 Query: 835 AGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGT------- 887 +GI+DA EI RVER+GLR M P+ AV+ +L DF DPLV +AD R+ +F G Sbjct: 823 SGIVDAAEIARVERTGLRQMKPELAVEASLCDFPRDPLVLAADRDRMRMFFGEKPVEKPG 882 Query: 888 DADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXXXXXXXXXXXXX 947 +ADTG G PA D AVR LAAVL Sbjct: 883 EADTGAG--------------PASMAPPD---AVRTQLAAVL-DVDAAALDLDSPLFDLG 924 Query: 948 XXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKETFSRD 997 TG +VPLATLLGG+T +LI L EK S D Sbjct: 925 VDSLLALDLRKRLKRLTGHTVPLATLLGGITGADLIAGLS--EKVNTSSD 972 >tr|Q7D790|Q7D790_MYCTU Tax_Id=1773 SubName: Full=Polyketide synthase, putative;[Mycobacterium tuberculosis] Length = 1009 Score = 637 bits (1643), Expect = e-180 Identities = 414/1018 (40%), Positives = 526/1018 (51%), Gaps = 49/1018 (4%) Query: 1 MMTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXX 60 +M L D RV V+LSAHAE+LI DA AI YL+ T ++VA Sbjct: 5 VMAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHR 64 Query: 61 AVIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY 120 AV+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AY Sbjct: 65 AVLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAY 121 Query: 121 R-LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALAR 179 R L YR D C SPL YL+A P + F +++I+GAQFVH VALA Sbjct: 122 RELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAE 180 Query: 180 VWRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGIT 239 VWRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 181 VWRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIG 240 Query: 240 PEQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHT 299 + A+ +IA T GWLEL GE FA+ I + FP HT Sbjct: 241 EQDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHT 300 Query: 300 TALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXX 359 + L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 301 SVLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 360 Query: 360 XXXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVIT 414 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 361 SAIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVS 420 Query: 415 VALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 421 AAVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERM 480 Query: 472 --AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISEND 529 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 481 VPSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTD 540 Query: 530 PVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMH 587 V A L + GLL YP + + V LVT E VD ++P AA+AAMH Sbjct: 541 AVRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMH 598 Query: 588 RSIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGM 646 RSI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 599 RSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTL 655 Query: 647 RDASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDE 704 DA A W +GVLDDVV+TGG GA+G+ + SR + V Sbjct: 656 ADA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAM 714 Query: 705 L--PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXX 762 L G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 715 LRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDN 774 Query: 763 XXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGR 822 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 775 FAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGR 834 Query: 823 RCTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFS 875 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+ Sbjct: 835 HCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFA 894 Query: 876 ADAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXX 935 ADA RL + L + Q P D + AVR LAAVL Sbjct: 895 ADAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAG 940 Query: 936 XXXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 941 EVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 998 >tr|A2VKA7|A2VKA7_MYCTU Tax_Id=348776 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis C] Length = 1009 Score = 637 bits (1643), Expect = e-180 Identities = 414/1018 (40%), Positives = 526/1018 (51%), Gaps = 49/1018 (4%) Query: 1 MMTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXX 60 +M L D RV V+LSAHAE+LI DA AI YL+ T ++VA Sbjct: 5 VMAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHR 64 Query: 61 AVIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY 120 AV+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AY Sbjct: 65 AVLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAY 121 Query: 121 R-LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALAR 179 R L YR D C SPL YL+A P + F +++I+GAQFVH VALA Sbjct: 122 RELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAE 180 Query: 180 VWRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGIT 239 VWRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 181 VWRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIG 240 Query: 240 PEQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHT 299 + A+ +IA T GWLEL GE FA+ I + FP HT Sbjct: 241 EQDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHT 300 Query: 300 TALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXX 359 + L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 301 SVLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVE 360 Query: 360 XXXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVIT 414 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 361 SAIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVS 420 Query: 415 VALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 421 AAVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERM 480 Query: 472 --AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISEND 529 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 481 VPSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTD 540 Query: 530 PVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMH 587 V A L + GLL YP + + V LVT E VD ++P AA+AAMH Sbjct: 541 AVRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMH 598 Query: 588 RSIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGM 646 RSI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 599 RSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTL 655 Query: 647 RDASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDE 704 DA A W +GVLDDVV+TGG GA+G+ + SR + V Sbjct: 656 ADA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAM 714 Query: 705 L--PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXX 762 L G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 715 LRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDN 774 Query: 763 XXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGR 822 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 775 FAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGR 834 Query: 823 RCTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFS 875 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+ Sbjct: 835 HCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFA 894 Query: 876 ADAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXX 935 ADA RL + L + Q P D + AVR LAAVL Sbjct: 895 ADAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAG 940 Query: 936 XXXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 941 EVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 998 >tr|Q7TYQ6|Q7TYQ6_MYCBO Tax_Id=1765 (mbtD)SubName: Full=POLYKETIDE SYNTHETASE MBTD (POLYKETIDE SYNTHASE);[Mycobacterium bovis] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|P71719|P71719_MYCTU Tax_Id=1773 (mbtD)SubName: Full=POLYKETIDE SYNTHETASE MBTD (POLYKETIDE SYNTHASE);[Mycobacterium tuberculosis] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|C6DNA3|C6DNA3_MYCTK Tax_Id=478434 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|C1AQU4|C1AQU4_MYCBT Tax_Id=561275 (mbtD)SubName: Full=Polyketide synthetase;[Mycobacterium bovis] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|A5WPZ6|A5WPZ6_MYCTF Tax_Id=336982 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|A5U574|A5U574_MYCTA Tax_Id=419947 (mbtD)SubName: Full=Putative polyketide synthase MbtD;[Mycobacterium tuberculosis] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|A1KL71|A1KL71_MYCBP Tax_Id=410289 (mbtD)SubName: Full=Polyketide synthetase mbtD;[Mycobacterium bovis] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|D6G568|D6G568_MYCTU Tax_Id=478435 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis KZN 605] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|D6FXX7|D6FXX7_MYCTU Tax_Id=611304 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis K85] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|D6FIU1|D6FIU1_MYCTU Tax_Id=611303 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis CPHL_A] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|D6F6H7|D6F6H7_MYCTU Tax_Id=611302 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis T46] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|D5ZGV6|D5ZGV6_MYCTU Tax_Id=537210 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis T17] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|D5YHK7|D5YHK7_MYCTU Tax_Id=520140 SubName: Full=Polyketide synthetase mbtd;[Mycobacterium tuberculosis EAS054] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|D5Y668|D5Y668_MYCTU Tax_Id=520141 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis T85] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|D5XVF1|D5XVF1_MYCTU Tax_Id=515617 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis T92] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|A4KJD1|A4KJD1_MYCTU Tax_Id=395095 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis str. Haarlem] Length = 1004 Score = 637 bits (1642), Expect = e-180 Identities = 414/1017 (40%), Positives = 525/1017 (51%), Gaps = 49/1017 (4%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M L D RV V+LSAHAE+LI DA AI YL+ T ++VA A Sbjct: 1 MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA 60 Query: 62 VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR 121 V+RA EL GLRALA G +HPL+ R++ GS R AFVFPGQG WP MG AYR Sbjct: 61 VLRAADRLELAEGLRALAAGREHPLIARSSL---GSAPRQAFVFPGQGGHWPGMGAVAYR 117 Query: 122 -LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARV 180 L YR D C SPL YL+A P + F +++I+GAQFVH VALA V Sbjct: 118 ELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTD-ERQAFCEIEIEGAQFVHAVALAEV 176 Query: 181 WRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITP 240 WRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LGI Sbjct: 177 WRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGE 236 Query: 241 EQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTT 300 + A+ +IA T GWLEL GE FA+ I + FP HT+ Sbjct: 237 QDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTS 296 Query: 301 ALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXX 360 L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 297 VLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVES 356 Query: 361 XXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNVITV 415 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+++ Sbjct: 357 AIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSA 416 Query: 416 ALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQV- 471 A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W ++ Sbjct: 417 AVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMV 476 Query: 472 -AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDP 530 + P H +AV+ L + A+A L A + E+ A A+ +LV+AP D Sbjct: 477 PSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDA 536 Query: 531 VLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAAMHR 588 V A L + GLL YP + + V LVT E VD ++P AA+AAMHR Sbjct: 537 VRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAAMHR 594 Query: 589 SIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR 647 SI FEHP+Q F LD+P LD + ALR V G TL+ R + Sbjct: 595 SIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFERTLA 651 Query: 648 DASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL 705 DA A W +GVLDDVV+TGG GA+G+ + SR + V L Sbjct: 652 DA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML 710 Query: 706 --PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXX 763 G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 711 RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF 770 Query: 764 XXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++GR Sbjct: 771 AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH 830 Query: 824 CTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSA 876 C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLVF+A Sbjct: 831 CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA 890 Query: 877 DAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXX 936 DA RL + L + Q P D + AVR LAAVL Sbjct: 891 DAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQAGE 936 Query: 937 XXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 937 VNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 993 >tr|A4T2C9|A4T2C9_MYCGI Tax_Id=350054 SubName: Full=Acyl transferase region;[Mycobacterium gilvum] Length = 960 Score = 623 bits (1607), Expect = e-176 Identities = 409/990 (41%), Positives = 513/990 (51%), Gaps = 50/990 (5%) Query: 7 LCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAG 66 L D R+PV+LSAHAE+LI DA +L +LD + VA AV+RA Sbjct: 2 LPDGRIPVLLSAHAEELIGEDARRLLGFLDSAPEV--DAVAATLLRVRRRNRHRAVVRAA 59 Query: 67 GLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR-LDDY 125 EL L ALA G +HPLV+R+A +P + RR AFV+PGQG+QWP+MG EAYR L DY Sbjct: 60 DRSELADALSALAAGQEHPLVSRSA--EPDAHRR-AFVYPGQGNQWPAMGAEAYRTLRDY 116 Query: 126 RAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHG 185 R D C SPL YL D+ T SQV+ Q AQF H VAL VWR+HG Sbjct: 117 RQAADVCAAAFTAAGAPSPLRYLT---DAAAVTG--SQVEAQAAQFTHAVALTAVWRAHG 171 Query: 186 VVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAE 245 V PD+TVGHSLGE+ AA+VAGAITL EA A+VIARATVL+ L YR+AVLG+TPE A Sbjct: 172 VAPDMTVGHSLGEVAAAHVAGAITLAEAAAVVIARATVLEGLADGYRMAVLGLTPEDAQS 231 Query: 246 VIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGV 305 +I PGWLEL GE FA+ + M FPAHT+ LDG+ Sbjct: 232 LIESVPGWLELAVVNAASSVGVSGERDAVDALLAQASSRGVFARSVTMAFPAHTSLLDGL 291 Query: 306 RADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXX 365 RAD LL RF +T + F+GSAT + V TDFADYW+ NLR TVRFD+ Sbjct: 292 RADFVRLLAPARFQQTAIPFLGSATGEAVPPETDFADYWFANLRNTVRFDRAAAAAVRAG 351 Query: 366 XXIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWR 425 +FVE+SAHPALLF++G +S + VGSGRRD PL E L+ + TVA DA + W Sbjct: 352 ANLFVEMSAHPALLFSLG---QSAGDALTVGSGRRDAPLVETLSAGIATVAAHDAEFPWH 408 Query: 426 DQLGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVS-GHHRIAV 484 D + L FP APMR+ HLWA P PLP LT+A E W E R AV Sbjct: 409 DVIDTTRPALRGFPNAPMRSVHLWALPQPLPAPPSLTLATEAWEPHRPAERGLALRRTAV 468 Query: 485 VGLDSECAVAGH-LRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRRIDE 543 + L G LRDA + G+ AD +L VAP + + D + L ID+ Sbjct: 469 LDLAGPRGGLGDLLRDAVDHHPGMVSTPVHDADLVLAVAPNLGDPDVRESVAALTALIDD 528 Query: 544 GLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLD 603 GLLRYPD + RD+WLVT E + D P AA+AAMHRSI FE+PD+ FR LD Sbjct: 529 GLLRYPDDVGTDCRDLWLVTTAAEQLTGD-PTPRPAQAALAAMHRSIGFEYPDRAFRHLD 587 Query: 604 V-PMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPW--PTGV 660 + P+ LD DLALR D+ P ++ R + W G Sbjct: 588 LPPVVLDEAAASAALDAVLGGGDDLALR-DIDGMP--AVFARTEHETVTTPESWADDPGA 644 Query: 661 LDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDELPLGVEIVAPRCDLTD 720 LD VVITGG+G VG + SR+G +G+ GV+ V CD+TD Sbjct: 645 LDHVVITGGSGTVGQHYARHLAERGARRITLLSRHGAKGSAAG--GPGVQTVC--CDVTD 700 Query: 721 IPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVR 780 + AAEFGG GA+L++H + + AWP R Sbjct: 701 PVALAVAAAEFGGDGATLVIHAAGTAQFAEHDTLSAAAFADTAAAKVEGLFRIAEAWPRR 760 Query: 781 PDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDA 840 P AR+L+CSSVSGLW NRL+DV A ++R+EG RC AVR+GL+ G GI+D Sbjct: 761 PGARMLVCSSVSGLWGGRGHAAYAAANRLVDVTAAQMRAEGIRCAAVRFGLF-GTGIVDE 819 Query: 841 DEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREATHA 900 + + + RSGL + PD AV +L+D GDP+V+SAD RL +F Sbjct: 820 ESVNLIGRSGLVPLDPDDAVAASLRDLPGDPIVYSADRARLQIF---------------- 863 Query: 901 AQHRDAGPP---ADAEHHDTGAAVRIALAAVLKXXXXXXXXXXXXXXXXXXXXXXXXXXX 957 D PP + A DT A V L +VL Sbjct: 864 --RDDPAPPTATSPASGGDTTAVVLAELTSVL-GIEPAGVDLDASLLDMGVDSLLALDLR 920 Query: 958 XXXXXTTGRSVPLATLLGGVTATELIEHLE 987 TGRSVPLA +LGG+T ELI L+ Sbjct: 921 KRLRRATGRSVPLAAMLGGMTGAELITGLD 950 >tr|Q73XY4|Q73XY4_MYCPA Tax_Id=1770 (mbtD)SubName: Full=MbtD;[Mycobacterium paratuberculosis] Length = 1013 Score = 617 bits (1590), Expect = e-174 Identities = 396/1006 (39%), Positives = 513/1006 (50%), Gaps = 49/1006 (4%) Query: 1 MMTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLD--GRTDTAPSDVAYXXXXXXXXXX 58 MM L D R+PV+LS+H +LI DA AIL YLD G + A VA Sbjct: 1 MMPTHGLPDGRIPVLLSSHDPELIRRDAAAILEYLDRIGESTEATGAVAATLLRLRRVRR 60 Query: 59 XXAVIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVE 118 A++RA EL AGL A+A G++H L+TR+A P R+AFVFPGQG+QW +MG + Sbjct: 61 HRALLRAADRAELAAGLGAIARGEEHALITRSARTTPP---RIAFVFPGQGNQWQAMGAD 117 Query: 119 AYRL-DDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVAL 177 AYRL YR DRC SPL YL++ PD +++ +IQGAQF H VAL Sbjct: 118 AYRLLPAYREAADRCAQAFVSAGFPSPLPYLVS-PDE----QSWTRPEIQGAQFTHAVAL 172 Query: 178 ARVWRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLG 237 A WR GV+P+IT+GHSLGE+ AAYVA AI+LP+AVA+V+ARATV+DRLTG Y +AVLG Sbjct: 173 AEAWRCFGVLPEITIGHSLGEVAAAYVAEAISLPDAVALVVARATVVDRLTGRYAMAVLG 232 Query: 238 ITPEQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPA 297 A ++A TPGW+E+ G+ FA ++ + +P Sbjct: 233 TGAADAESLLATTPGWVEVSAVNGPASTVVAGDHDAVAAAVRLARQREIFAHQLFVDYPG 292 Query: 298 HTTALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQX 357 HT+AL +RA L L P F ++P++FIGS V TD+A YWY NL +TVRFD Sbjct: 293 HTSALRPLRAALAELTPQSAFRDSPIRFIGSTRGAEVAATTDYASYWYENLCSTVRFDLA 352 Query: 358 XXXXXXXXXXIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVAL 417 FVELSAHP+LL+ + +++ V+VGSG RD P+ E L+ ++ VA Sbjct: 353 VQCARSCGADAFVELSAHPSLLYPLSGIIDD-ESAVIVGSGHRDRPITESLSASMAAVAT 411 Query: 418 ADAGYRWRDQLGDCH-AVLPDFPFAPMRAEHLWAQPDPL---PPVTGLTVAAEQWHQVAV 473 AD GYRW + + + L FP APMRA HLWA PD + P LTVA E W Sbjct: 412 ADPGYRWSETVPTPNQPALHGFPNAPMRATHLWAAPDRVTEAAPRPRLTVAVEDWRHTTS 471 Query: 474 PEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLA 533 P A +G + L DAA G VVAP A+ L +VAP + + D V A Sbjct: 472 PTTP---TAADLGFAGAHPLTRRLADAAAAQGGCRVVAPGEAEILAIVAPELDQLDAVAA 528 Query: 534 GEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFE 593 E++G R D GL Y L+ R VWL+T R EHV D D + AA+AAMHRSI FE Sbjct: 529 VEQIGAREDAGLPDYRGLIGPRCRAVWLLTVRAEHVDGDDDQACVAQAALAAMHRSIGFE 588 Query: 594 HPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASA- 651 PDQ F LD+P +D ++ALR G RR +R A Sbjct: 589 FPDQAFGHLDLPHRDVDAATAHAIIEVLLAEPAEVALR-------GEQSPRRHVRTFRAH 641 Query: 652 ---AAAPWPTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL--P 706 A P L+ VVITGG+GA+GL + SRNGIE + EL Sbjct: 642 NESADRPLDDAALEHVVITGGSGAIGLHYARYCLQRGTRNLTLLSRNGIEAAVLRELTGS 701 Query: 707 LGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXX 766 + APRCD+TD V AA + G GA+L++H Sbjct: 702 HDARVSAPRCDITDRAAVTQAAARYAGSGATLLIHTAGIAQARSRTDLTGADVAAVCAAK 761 Query: 767 XXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTA 826 + + WP+RPD RIL CSSV G+W NR+LDV+A +LR+ G CTA Sbjct: 762 VRGLALMADVWPLRPDCRILACSSVFGVWGGYHHAAYAASNRMLDVLATQLRARGLDCTA 821 Query: 827 VRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLG 886 +RWGLW AG++ EI R ERSGL AM P RA+ +L + DPL+F AD +RL +F Sbjct: 822 IRWGLWQDAGVVAGSEIARTERSGLVAMDPRRALQASLHRYESDPLIFDADFERLQVFFE 881 Query: 887 TD------ADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXXXXXX 940 + +DT T + AA AG P VR LAA L Sbjct: 882 SQGMPMPFSDTPTRDDEAAAA---PAGKP-------LAELVRAELAATLHLGDSVSIDPS 931 Query: 941 XXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHL 986 T G SVP+A +LGG+T EL++ L Sbjct: 932 ASLIDLGVDSLLALDLRKRLRRTVGNSVPVARMLGGITVAELVDAL 977 >tr|A0QE93|A0QE93_MYCA1 Tax_Id=243243 SubName: Full=MbtD protein;[Mycobacterium avium] Length = 1013 Score = 613 bits (1580), Expect = e-173 Identities = 392/1006 (38%), Positives = 513/1006 (50%), Gaps = 49/1006 (4%) Query: 1 MMTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLD--GRTDTAPSDVAYXXXXXXXXXX 58 MM L D R+PV+LS+H +LI DA AIL YLD G + A VA Sbjct: 1 MMPTHGLPDGRIPVLLSSHDPELIRRDAAAILEYLDRIGESTEATGAVAATLLRLRRVRR 60 Query: 59 XXAVIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVE 118 A++RA EL AGL A+A G++H L+TR+A P R+AFVFPGQG+QW +MG + Sbjct: 61 HRALLRAADRAELAAGLAAIARGEEHALITRSARTTPP---RIAFVFPGQGNQWQAMGAD 117 Query: 119 AYR-LDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVAL 177 AYR L YR DRC SPL YL++ PD +++ +IQGAQF H VAL Sbjct: 118 AYRRLPAYREAADRCAQAFVAAGFPSPLPYLVS-PDE----QSWTRPEIQGAQFTHAVAL 172 Query: 178 ARVWRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLG 237 A WR GV+P++ +GHSLGE+ AAYVA AI+LP+AVA+V+ARATV+DRLTG Y +AVLG Sbjct: 173 AEAWRCFGVLPEMAIGHSLGEVAAAYVAEAISLPDAVALVVARATVVDRLTGRYAMAVLG 232 Query: 238 ITPEQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPA 297 A ++A TPGW+E+ G+ FA ++ + +P Sbjct: 233 AGAADAESLLATTPGWVEVSAVNGPASTVVAGDHDAVAAAVRLAQQREIFAHQLFVDYPG 292 Query: 298 HTTALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQX 357 HT+AL +RA L L P F ++P++FIGS V TD+A YWY NL +TVRFD Sbjct: 293 HTSALRPLRAALAELTPQSAFRDSPIRFIGSTRGAEVAATTDYASYWYENLCSTVRFDLA 352 Query: 358 XXXXXXXXXXIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVAL 417 FVELSAHP+LL+ + +++ V+VGSG RD P+ E L+ ++ VA Sbjct: 353 VQCARSCGADAFVELSAHPSLLYPLSGIIDD-ESAVIVGSGHRDRPITESLSASMAAVAT 411 Query: 418 ADAGYRWRDQLGDCH-AVLPDFPFAPMRAEHLWAQPDPL---PPVTGLTVAAEQWHQVAV 473 AD GYRW + + + L FP APMRA HLWA PD + P LTVA E W Sbjct: 412 ADPGYRWSETVPTRNQPALHGFPNAPMRATHLWAAPDRVTEAAPRPRLTVAVEDWRHTTS 471 Query: 474 PEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLA 533 P A +G + L DAA G VVAP A+ + +VAP + + D V A Sbjct: 472 PTTP---TAADLGFAGAHPMTRRLADAAAAQGGCRVVAPGEAEIVAIVAPELDQLDAVAA 528 Query: 534 GEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFE 593 E++G R D GL Y L+ R VWL+T R EHV D D + AA+AAMHRSI FE Sbjct: 529 VEQIGAREDAGLPDYRGLIGPRCRAVWLLTVRAEHVDGDDDQACVAQAALAAMHRSIGFE 588 Query: 594 HPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASA- 651 PDQ F +D+P +D ++ALR G RR +R A Sbjct: 589 FPDQAFGHVDLPHRDVDAATAYAIIEVLLAEPAEVALR-------GEQSPRRHVRTFRAH 641 Query: 652 ---AAAPWPTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL--P 706 A P L+ VVITGG+GA+GL + SRNGIE + EL Sbjct: 642 HESADRPLDDAALEHVVITGGSGAIGLHYARYCLQRGARNLTLLSRNGIEAAVLRELTGS 701 Query: 707 LGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXX 766 + APRCD+TD V + AA + G GA+L++H Sbjct: 702 HDARVSAPRCDITDRAAVTEAAARYAGSGATLLIHTAGIAQARSRTDLTGADVAAVCAAK 761 Query: 767 XXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTA 826 + + WP+RPD RIL CSSV G+W NR+LDV+A +LR+ G CTA Sbjct: 762 VRGLALMADVWPLRPDCRILACSSVFGVWGGYHHAAYAASNRMLDVLATQLRARGLDCTA 821 Query: 827 VRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLG 886 +RWGLW AG++ EI R ERSGL AM P RA+ +L + DPL+F AD +RL +F Sbjct: 822 IRWGLWQDAGVVAGSEIARTERSGLVAMDPRRALQASLHRYESDPLIFDADFERLQVFFE 881 Query: 887 TD------ADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXXXXXX 940 + +DT T + AA AG P VR LAA L Sbjct: 882 SQGMPMPFSDTPTRDDEAAAA---PAGKP-------LAEVVRAELAATLHLGDSVSIDPS 931 Query: 941 XXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHL 986 T G SVP+A +LGG+T EL++ L Sbjct: 932 ASLIDLGVDSLLALDLRKRLRRTVGNSVPVARMLGGITVAELVDAL 977 >tr|D5PHG3|D5PHG3_9MYCO Tax_Id=525368 (mbtD2)SubName: Full=Mycobactin biosynthesis enzyme MbtD; Flags: Fragment;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 957 Score = 588 bits (1517), Expect = e-165 Identities = 373/941 (39%), Positives = 484/941 (51%), Gaps = 38/941 (4%) Query: 61 AVIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY 120 AV+RA EL AGL AL G++HPLV R++ G+ +AFVFPGQG+QW +MG +AY Sbjct: 14 AVVRAADRAELAAGLSALTRGEEHPLVHRSSL---GAAPCIAFVFPGQGNQWQAMGAQAY 70 Query: 121 -RLDDYRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALAR 179 RL YRAE +RC SPL YL +GV D+S+ ++QGAQF H V+LA Sbjct: 71 QRLPAYRAEAERCAREFRTAGLPSPLPYL-----TGVRDRDWSRTEVQGAQFTHAVSLAH 125 Query: 180 VWRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGIT 239 WR HGV+P +TVGHSLGE+ AAYVAG ++LP+AVA+V ARA ++D+L+G Y +AV G Sbjct: 126 EWRCHGVLPAMTVGHSLGEVAAAYVAGTVSLPDAVALVGARAAIIDQLSGRYAMAVFGAD 185 Query: 240 PEQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHT 299 +A +IAET GWLE+ G+ F ++ + +P HT Sbjct: 186 MGEAESLIAETAGWLEVSAVNGPSSTVVSGDHEAVAAAVRLARQRGMFTHQLSVDYPGHT 245 Query: 300 TALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXX 359 + L +RA L L+P F ++PV+F+GS V DFADYWY NL TVRFD+ Sbjct: 246 SVLRQLRARLVELIPESAFRDSPVRFVGSTFGAQVGPDADFADYWYENLCNTVRFDRAVE 305 Query: 360 XXXXXXXXIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALAD 419 FVE+SAHP+LL+ + +L++ R V+VGSG RD + E LA N+ VA AD Sbjct: 306 SARKLGASAFVEMSAHPSLLYPLADLVDE-RTTVVVGSGHRDGAVTEVLAANIAAVAAAD 364 Query: 420 AGYRWRDQL-GDCHAVLPDFPFAPMRAEHLWAQPDP---LPPVTGLTVAAEQWHQVAVPE 475 G RW + + G L FP APMR HLWA P+P PP LT A E W Q E Sbjct: 365 PGCRWANAIPGGARPPLRGFPNAPMRTVHLWAAPEPPIEAPPGPALTAAVEHWRQAIPSE 424 Query: 476 VSGHHRIAVVGLDSECAVAGH-LRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAG 534 +G I +V +D H L +A E +V+P A+ L +VAP + D A Sbjct: 425 ATGAD-IGIVAIDPADGPLPHRLTEAVEARRDCRLVSPHDAEILAIVAPALDTADATAAI 483 Query: 535 EELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHV-PVDRDGSLPVGAAVAAMHRSIAFE 593 ++L R D GL Y L+ R VWL+T R E V P D D + P AA+AAMHRS+ FE Sbjct: 484 DQLAARPDAGLPDYAALIGPRCRAVWLLTARAETVGPGDAD-AWPAQAALAAMHRSVGFE 542 Query: 594 HPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDA--S 650 DQ F LD+ D ++ALR G + R RD + Sbjct: 543 FADQAFGHLDLAGRDADARTASAVVDALLGEPGEVALR----GGATPRAYVRTFRDCRDT 598 Query: 651 AAAAPWPTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDELPL--G 708 AA P L+ VVITGG+GA+GLQ+ SRNGI + + L G Sbjct: 599 AAGPPLDAAALEHVVITGGSGAIGLQYARYCIERGARTVTLLSRNGIGRDALRRLTENHG 658 Query: 709 VEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXX 768 ++ APRCD+TD VR VAA G GASL++H Sbjct: 659 ADVHAPRCDITDPAAVRAVAARHAGTGASLLIHTAGIAEAHSRSDLTGEGVAAVCAAKVR 718 Query: 769 XIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVR 828 + + +WP+RPD RIL CSSV G+W NR+LDV+A +LR GR CTA+R Sbjct: 719 GLALLAGSWPLRPDCRILACSSVFGVWGGHGHAAYAASNRMLDVLAAQLRGTGRDCTAIR 778 Query: 829 WGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFL--- 885 WGLW AG++ ADEI R ERSGL AM P RA++ L + GDPL+F AD RL +F Sbjct: 779 WGLWQAAGVVAADEIARTERSGLIAMVPARAIEAGLYRYDGDPLIFDADPDRLGVFFESQ 838 Query: 886 GTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXXXXXXXXXXXXX 945 G R A R A P A+ VR LAA L Sbjct: 839 GMAMPFDVPRGDDGGADGRPAKPLAE--------VVRDELAATLHLGDSLSIDTSAPLID 890 Query: 946 XXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHL 986 T G SVP+A +LGG+T ELI+ L Sbjct: 891 LGVDSLLALDLRKRLRRTVGSSVPVARMLGGITLDELIDAL 931 >tr|D5Z5Q4|D5Z5Q4_MYCTU Tax_Id=537209 SubName: Full=Polyketide synthetase mbtD;[Mycobacterium tuberculosis GM 1503] Length = 853 Score = 511 bits (1317), Expect = e-142 Identities = 333/840 (39%), Positives = 428/840 (50%), Gaps = 44/840 (5%) Query: 178 ARVWRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLG 237 A VWRS GV+PD+TVGHSLGE+ AAY+AG+ITL +AVA+V ARA V+ RL G Y VA LG Sbjct: 23 AEVWRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALG 82 Query: 238 ITPEQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPA 297 I + A+ +IA T GWLEL GE FA+ I + FP Sbjct: 83 IGEQDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPV 142 Query: 298 HTTALDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQX 357 HT+ L+ +R +L LP F E PVQFIG T DVV GT F DYWY NLR TVRFD+ Sbjct: 143 HTSVLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRA 202 Query: 358 XXXXXXXXXXIFVELSAHPALLFNMGELLESTRGV-----VLVGSGRRDEPLPERLADNV 412 F+E+SAHPALLF +G+ E + VLVGS RR E + L+ N+ Sbjct: 203 VESAIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANI 262 Query: 413 ITVALADAGYRWRDQLG---DCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWH 469 ++ A+AD GY W D G D L FP APMRA +WA P+PLPPV+GLT+A E+W Sbjct: 263 VSAAVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWE 322 Query: 470 QV--AVPEVSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISE 527 ++ + P H +AV+ L + A+A L A + E+ A A+ +LV+AP Sbjct: 323 RMVPSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEH 382 Query: 528 NDPVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVG--AAVAA 585 D V A L + GLL YP + + V LVT E VD ++P AA+AA Sbjct: 383 TDAVRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQ--VDAADAVPSAGQAALAA 440 Query: 586 MHRSIAFEHPDQNFRQLDVP-MGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRR 644 MHRSI FEHP+Q F LD+P LD + ALR V G TL+ R Sbjct: 441 MHRSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSV---NGYTLFER 497 Query: 645 GMRDASAAAAPW--PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRV 702 + DA A W +GVLDDVV+TGG GA+G+ + SR + V Sbjct: 498 TLADA-PAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATV 556 Query: 703 DEL--PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXX 760 L G IV+P CD+TD ++ +AAE+GG GASLIVH Sbjct: 557 AMLRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVV 616 Query: 761 XXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSE 820 + ++ WP+RPD R LLCSSV G+W NRLLDVMA +LR++ Sbjct: 617 DNFAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQ 676 Query: 821 GRRCTAVRWGLW-------PGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLV 873 GR C AV+WGLW P GI DA I RVERSGLR MAP +A++ +L +F DPLV Sbjct: 677 GRHCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLV 736 Query: 874 FSADAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXX 933 F+ADA RL + L + Q P D + AVR LAAVL Sbjct: 737 FAADAARLQMLL-------------DSRQFERYEGPTD-PNLTIVDAVRTQLAAVLGIPQ 782 Query: 934 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKET 993 + G +V LATL+G +T L+ LE ++ + Sbjct: 783 AGEVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERS 842 >tr|Q83ZY9|Q83ZY9_MYCSM Tax_Id=1772 (mbtD)SubName: Full=Polyketide synthase; Flags: Fragment;[Mycobacterium smegmatis] Length = 360 Score = 470 bits (1209), Expect = e-130 Identities = 258/363 (71%), Positives = 260/363 (71%), Gaps = 4/363 (1%) Query: 635 DGPGTTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSR 694 D P + R + SA A TGVLDDVVITGGTGAVGLQF SR Sbjct: 2 DNPVAPRYARRVGRGSAVA----TGVLDDVVITGGTGAVGLQFARRLAGLGARRIVLLSR 57 Query: 695 NGIEGNRVDELPLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXX 754 NGIEGNRVDELPLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVH Sbjct: 58 NGIEGNRVDELPLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHAAATATIAAGSAL 117 Query: 755 XXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMA 814 IENVLAAWPVRPDARILLCSSVSGLW NRLLDVMA Sbjct: 118 TGAAAQATFTAKLAGIENVLAAWPVRPDARILLCSSVSGLWGGHGHAARTAANRLLDVMA 177 Query: 815 ERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVF 874 ERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDF GDPLVF Sbjct: 178 ERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFRGDPLVF 237 Query: 875 SADAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKXXXX 934 SADAQRLALFLGTD DTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLK Sbjct: 238 SADAQRLALFLGTDPDTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLKLADT 297 Query: 935 XXXXXXXXXXXXXXXXXXXXXXXXXXXXTTGRSVPLATLLGGVTATELIEHLERPEKETF 994 TTGRSVPLATLLGGVTATELIEHLERPEKETF Sbjct: 298 TGLDLDASLLDLGVDSLLALDLRKKLKKTTGRSVPLATLLGGVTATELIEHLERPEKETF 357 Query: 995 SRD 997 SRD Sbjct: 358 SRD 360 >tr|D0L269|D0L269_GORB4 Tax_Id=526226 SubName: Full=Acyl transferase;[Gordonia bronchialis] Length = 1560 Score = 305 bits (782), Expect = 2e-80 Identities = 281/994 (28%), Positives = 401/994 (40%), Gaps = 80/994 (8%) Query: 7 LCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAG 66 L D PVV+SA L+ + ++ YL +P ++ A++ A Sbjct: 6 LPDGTSPVVVSADTPALLRAEGASLADYLTRAPHVSPDQLSRMLFRSRPVRRFRALVSAR 65 Query: 67 GLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDD-Y 125 L GLRA+A G DHP V R+ P R R+A VFPGQG Q P MG +R + Sbjct: 66 DAAALVEGLRAVATGTDHPAVVRSDGP--ARRSRIALVFPGQGGQRPGMGALYHRHSAAF 123 Query: 126 RAEVDRCXXXXXXXXXXSPLDYLLAH-PDSGVSTNDFSQVQIQGAQFVHGVALARVWRSH 184 AEV+R SP YLL PD S +D + + IQ A F+ ALA +WRS Sbjct: 124 AAEVERLHAVFEEVAGCSPRSYLLDDDPDRDTSADDTAAL-IQPALFMQMAALAAMWRSF 182 Query: 185 GVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTG-PYRVAVLGITPEQA 243 GVVP+I VGHS GEI A YVAG + L +A+ ++ RA +D Y +AVL +A Sbjct: 183 GVVPEIVVGHSQGEIAACYVAGVMDLHDAITVLTTRARSVDTTASQQYSMAVLDTDRAEA 242 Query: 244 AEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALD 303 ++A GW E+ G+ F++ I + +PAHT + Sbjct: 243 ESLLARRSGWAEISVINSPRMTGVSGDTPIITSVVDQLAEAGRFSRVIAVRYPAHTAVMH 302 Query: 304 GV-RADLDAL---LPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXX 359 V R LDA L F TP+ IGS + +T +YW+ NLR VRFD+ Sbjct: 303 EVARTILDATGERLSDKGFTATPITCIGSTLGEEITPDLPLGEYWFWNLRNVVRFDKAVA 362 Query: 360 XXXXXXXXIFVELSAHPALLFNMGELLESTRG--VVLVGSGRRDEPLPERLADNVITVAL 417 FVELS HP L +GE LES +VG+ RR +A N++ +A+ Sbjct: 363 RAVALGANTFVELSEHPTLQLPIGETLESIADATATVVGTSRRQAEDMSVIARNLVLIAV 422 Query: 418 ADAGYRWRDQL-------GDCHAVLPDFPFAPMRAEHLWA-----QPDPLPPVTGLT--- 462 D + W L G LPDFP LW +P+ PP G + Sbjct: 423 GDLDFDWTSLLVEDDTARGSAALPLPDFPHTITNDSFLWMTYATNRPEVSPPHAGTSAPA 482 Query: 463 ----------VAAEQWHQVAVPEVSGHHRIAVVGLDS----ECAVAGHLRDAAERIEGVE 508 A++W ++ + + +V L + A+ H D ++ Sbjct: 483 TPAAVPDPTMTVAQRWVRIPRRSMVAPQTMGIVDLGALPGLADAIVEHAPDFGAAARRID 542 Query: 509 VVAPAA--------ADTLLVVAPMISENDPVLA--GEELGRRIDEGLLRYPDLLTETTRD 558 V A ++ DT++V+ P + A E +G+ D R + RD Sbjct: 543 VAAESSDDATLLDGVDTVVVLGPAGAREPRADARTREAIGQAADFFGERRWWSAADPPRD 602 Query: 559 VWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDV-PMGLDXXXXXXXX 617 WLVT GE V D + A +AA R + E+P+ +F LD+ P L+ Sbjct: 603 HWLVTVGGEAV-TDNESPEIGAAGIAAGFRCLGAEYPNASFGHLDLDPALLETGTVDAAV 661 Query: 618 XXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQF 677 +A D+A G L+ + + A A V+ITGGTG VGL+F Sbjct: 662 ADKIVAALHIAREPDIA-LRGKDLFVKRLTPADDTATAETPAAGRHVLITGGTGKVGLEF 720 Query: 678 XXXXXXXXXXXXXXXSRNGIE---GNRVDELPL-GVEIVAPRCDLTDIPRVRDVAAEFGG 733 SR G R+D L G E+V RCD+TD +VR + Sbjct: 721 ADHFAAQGVTRLTLVSRRGATPEVQRRLDALRRNGTEVVVQRCDITDDAQVRALGESLAD 780 Query: 734 QGASLIVH----XXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCS 789 + +H + +L A P D R+LLCS Sbjct: 781 APVDVAIHAAADLPPGTGGIGLEDITGDVVSRLCDAKVAGVHRILGAVPTSDDVRVLLCS 840 Query: 790 SVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLW---PGAGIIDADEITRV 846 S + NR+LD +A LR++G C +V+WG W G+G DA + V Sbjct: 841 SFAATIGGRGTIVYSAANRMLDAVATALRADGVDCASVQWGQWAVHDGSGAADAATLAAV 900 Query: 847 ERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLG-----------TDADTGTGR 895 G R M + A+ L + +V + D QR L A+ R Sbjct: 901 ---GYRTMPSESAIRAGLA-VRHNAIVAAFDWQRGHEVLRDFGYGPLLSDLASAEPAPPR 956 Query: 896 EATHAAQHRDAGPPADAEHHDTGAAVRIALAAVL 929 +T A GP A D A +A V+ Sbjct: 957 PSTRPAADSTPGPAAPQPVRDLRTAALAVVADVI 990 >tr|B2HM91|B2HM91_MYCMM Tax_Id=216594 (mbtD)SubName: Full=Polyketide synthase MbtD;[Mycobacterium marinum] Length = 1024 Score = 302 bits (774), Expect = 1e-79 Identities = 264/935 (28%), Positives = 380/935 (40%), Gaps = 70/935 (7%) Query: 7 LCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAG 66 L D +PV+LSA +L+ +ATA+ ++ D P ++ A+ Sbjct: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFRTRAARRHRALAMVR 67 Query: 67 GLDELTAGLRALADGDDHPLVTRAAAPQPGS-RRRVAFVFPGQGSQWPSMGVEAYR-LDD 124 EL L+A+ D +HP + R P + RRR+ +VFPGQG Q P MG Y + Sbjct: 68 TRAELIDALQAMIDRYEHPALIRT---DPAAIRRRIGYVFPGQGGQRPGMGQLFYESVPA 124 Query: 125 YRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSH 184 +RAEVDRC SP +YLL D +D S +Q A F ALA +WRS Sbjct: 125 FRAEVDRCAQAFEAQSCGSPRNYLL---DKNFQ-DDGSAGIVQPALFTQMAALAAMWRSF 180 Query: 185 GVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRL-TGPYRVAVLGITPEQA 243 G+ P++T+GHS GE+ AAYV+G ITL +AV ++ RA D Y +A++ E Sbjct: 181 GIAPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRAHAADEFAAADYAMAIVAADRETC 240 Query: 244 AEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTAL- 302 +++A GW +L GE FA+ I + +PAHT+ + Sbjct: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 Query: 303 ---DGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXX 359 D +RA + L F +T + +G+ +T+ DYW+ NLR VRFD+ Sbjct: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA 360 Query: 360 XXXXXXXXIFVELSAHPALLFNMGELLESTRG------VVLVGSGRRDEPLPERLADNVI 413 FVEL+ HP L + E L + R ++VG+ R N+ Sbjct: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 Query: 414 TVALADAGYRW---RDQLGDCHAV-LPDFPFAPMRAEHLW-------------------- 449 +A+ D Y W R + A+ L DFP M LW Sbjct: 421 QLAVHDLNYPWECLRAEPDGAQALPLLDFPNTRMNEIRLWLPYDEVLPRRQPPSVSVAPA 480 Query: 450 --AQPDPLPPVTGLTVAAEQWHQVAVPEVSGHHRIAVVGLDSECA-------VAGHLRDA 500 + PD T + E+W +++ ++ + +V CA A H A Sbjct: 481 APSVPDATADTTPARLLVEEWVRLSQRSLTPPRVVGIVDPTGACAQLATAMTAAAHQAGA 540 Query: 501 AER-IEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDV 559 R + G A +TL+++ P + D A E+G +P + T T D Sbjct: 541 TARVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAW-WPGVDTGVT-DC 598 Query: 560 WLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDVPMG--LDXXXXXXXX 617 WLVT GE PV AA +A RSI EHP FR LD+P G Sbjct: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVA 658 Query: 618 XXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQF 677 +LA R D A + G A A P + V+I GGTG +GL+F Sbjct: 659 ALHTANEPELAYR-DGAFYAKRIVAGEGAVVHGAGACP------EHVLIIGGTGNLGLEF 711 Query: 678 XXXXXXXXXXXXXXXSRNGIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVAAEFG 732 SR+G + L +I RCD+ D V +AA+ Sbjct: 712 CDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHR 771 Query: 733 GQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVS 792 A LI+H I VL A+P RI+LCSS Sbjct: 772 STPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSAR 831 Query: 793 GLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLR 852 NR+LD MA RLR+EG C +V+WG W +DA + ++ G+ Sbjct: 832 ATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVI 891 Query: 853 AMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGT 887 M P A+ +Q + +V + D R L T Sbjct: 892 PMPPAEAIALGMQRLGRNAIVAAFDFDRARPVLET 926 >tr|Q5Z1T1|Q5Z1T1_NOCFA Tax_Id=37329 (nbtC)SubName: Full=Putative polyketide synthase;[Nocardia farcinica] Length = 1028 Score = 302 bits (773), Expect = 2e-79 Identities = 291/968 (30%), Positives = 396/968 (40%), Gaps = 63/968 (6%) Query: 2 MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXA 61 M+ L D VPV++S+ D + +A A+L YLD +P VA A Sbjct: 1 MSSYLLPDGTVPVLISSDTADGVRAEAAAVLAYLDEHPRVSPERVAEMLFRTRVARRYRA 60 Query: 62 VIRAGGLDELTAGLRAL-ADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY 120 + +EL GLRA+ AD +VT A S RR+ FVFPGQGSQ P MG Y Sbjct: 61 LAMVRTREELLDGLRAVVADTPSRVVVTGDGA---ASARRIGFVFPGQGSQRPGMGRLYY 117 Query: 121 RLDD-YRAEVDRCXXXXXXXXXXS-PLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALA 178 + D YRA VD C PL YLL D G + +VQ A H LA Sbjct: 118 DVSDAYRAAVDACAAIHRERFEHDQPLHYLLG--DEGRYQDTVWEVQ--PALMFHMYGLA 173 Query: 179 RVWRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGP-YRVAVLG 237 +WR+ GV P TVGHS GE+ A V+ +TL ++V V RA +++R++ Y +AVLG Sbjct: 174 AMWRAAGVEPAATVGHSQGELAAGAVSAVMTLRDSVLAVTHRARLVERISPRGYSMAVLG 233 Query: 238 ITPEQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPA 297 + E+ ++A GW EL G+ FA+EI++ +PA Sbjct: 234 MDREECEALLARHSGWAELSVVNAPHILAISGDRDTIVDMVELATARGQFAREIKVSYPA 293 Query: 298 HTTALDGVRADLDALLP---AGR-FAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVR 353 HT+ + +R + L +G F + + G+ +T DYWY NLR VR Sbjct: 294 HTSIVAELREHFMSFLGDEMSGECFTASEIPCYGATLGAAITPDLTHRDYWYWNLRNRVR 353 Query: 354 FDQXXXXXXXXXXXIFVELSAHPALLFNMGELLEST--------RGVVLVGSGRRDEPLP 405 FD+ +E++ HP L + E L R V ++G+ R Sbjct: 354 FDRAVVAAVTDGVDTLIEVAEHPVLQLALQENLTLVPREKLPLGRDVKVLGTSLRTAEGL 413 Query: 406 ERLADNVITVALADAGYRWRDQLGDCHAV----LPDFPFAPMRAEHLWAQPDPLPPVTGL 461 N+ T+A+ D YRW D A L DFP M LWA PD LP Sbjct: 414 AEFTRNLATIAVHDLDYRWDALRTDDGAAPRPPLRDFPHTIMHPRRLWAGPD-LPAAEPQ 472 Query: 462 TVAA-------EQWHQVAVPEVSGHHRIAVVGLDSECA-VAGHLRDAAERIEGVEVVAPA 513 AA E W + + +AVV CA +A L AA+R V A Sbjct: 473 PDAAPAPERLVETWIPLDKRSMLAPRTLAVVDHTGRCAELADALVAAADRHGATATVLDA 532 Query: 514 AA--------DTLLVVAPMISENDPVLAGEELGRRI-DEGLLRYPDLLTETTRDVWLVTG 564 AA DT +V+ P + + D A ++ D + D L + WLVT Sbjct: 533 AALAGDLPEFDTAVVLLPELPDTDGAAALDDFAAFFADRTWVPALDRLGPGGQ-CWLVTT 591 Query: 565 RGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDVPMGLDXXXXXXXXXXXXXXX 624 GE V D AVAA +RS E P R LD+ G Sbjct: 592 GGESVLADDPVPHLFHGAVAAGYRSAGIERPGILLRHLDLAAGAGPDQAARIVTAVHT-- 649 Query: 625 XDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQFXXXXXXX 684 A C++A G +R + D + A+ T L V+I GGTG +GL+F Sbjct: 650 ---AGECELALRGGKLYVKRLVVDPATDASAADTD-LSHVLIVGGTGQLGLRFCEHFAHA 705 Query: 685 XXXXXXXXSRNGI------EGNRVDELPLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASL 738 SR+G E NR+ L G EIV CD++D V+ AA SL Sbjct: 706 GAGRVTLVSRSGETERVAGELNRLRRLG-GTEIVVEACDVSDAEAVKRFAATIESAPVSL 764 Query: 739 IVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXX 798 ++H + VL P RILLCSS + Sbjct: 765 LIHAAVNYVDAELPDITAEMVTEAAGSKVLGLGTVLDIVPFTEQQRILLCSSTAATLSGR 824 Query: 799 XXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDR 858 NR+LD++A RLR++GR ++ WGLW AG +D RV +G+ MAP Sbjct: 825 GQILYAVTNRMLDILARRLRAQGRDAISIEWGLWSVAGPLDEAGFARVADAGVHPMAPRD 884 Query: 859 AVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGRE----ATHAAQHRDAGPPADAEH 914 A+ L GD ++ SAD L L T E A +A D P E Sbjct: 885 AITAGLAGPWGDAMIMSADWAFLREVLDTFGQGSVLPEIATPAAASAPEPDVAEPVVTEQ 944 Query: 915 HDTGAAVR 922 AA R Sbjct: 945 PAAPAADR 952 >tr|A0PTV2|A0PTV2_MYCUA Tax_Id=362242 (mbtD)SubName: Full=Polyketide synthase MbtD;[Mycobacterium ulcerans] Length = 1024 Score = 291 bits (744), Expect = 4e-76 Identities = 261/933 (27%), Positives = 378/933 (40%), Gaps = 72/933 (7%) Query: 7 LCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAG 66 L D +PV+LSA +L+ +ATA+ ++ D P ++ A+ Sbjct: 8 LPDGTIPVLLSADTPELLDSEATALRDHVAAHPDLTPGPISAMLFRTRAARRHRALAMVR 67 Query: 67 GLDELTAGLRALADGDDHPLVTRAAAPQPGS-RRRVAFVFPGQGSQWPSMGVEAYR-LDD 124 EL L+A+ D +HP + R P + RRR+ +VFPGQG Q P MG Y + Sbjct: 68 TRAELIDALQAMIDRYEHPALIRT---DPAAIRRRIGYVFPGQGGQRPGMGQLFYESVPA 124 Query: 125 YRAEVDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSH 184 +RAEVDRC SP +YLL D +D S +Q A F ALA +WRS Sbjct: 125 FRAEVDRCAQAFEAQACGSPRNYLL---DKNFQ-DDGSAGIVQPALFTQMAALAAMWRSF 180 Query: 185 GVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRL-TGPYRVAVLGITPEQA 243 + P++T+GHS GE+ AAYV+G ITL +AV ++ RA D Y +A++ E Sbjct: 181 DIPPNVTIGHSQGEVAAAYVSGTITLEDAVRVIGIRAHAADEFAAADYAMAIVAADREAC 240 Query: 244 AEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTAL- 302 +++A GW +L GE FA+ I + +PAHT+ + Sbjct: 241 EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTEGGTFARVIRVRYPAHTSLIH 300 Query: 303 ---DGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXX 359 D +RA + L F +T + +G+ +T+ DY + NLR VRFD+ Sbjct: 301 DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYCFWNLRNIVRFDKAIA 360 Query: 360 XXXXXXXXIFVELSAHPALLFNMGELLESTRG------VVLVGSGRRDEPLPERLADNVI 413 FVEL+ HP L + E L + R ++VG+ R N+ Sbjct: 361 AAVQRDVETFVELAEHPTLQLAIHENLAALRDEADDRPAMVVGTSERTATDLGEFTRNLA 420 Query: 414 TVALADAGYRW---RDQLGDCHAV-LPDFPFAPMRAEHLW-------------------- 449 +A+ D Y W R + A+ + DFP M LW Sbjct: 421 QLAVHDLNYPWECLRAEPDGAQALPMLDFPNTRMNEIRLWLPYDEVLPRRQPPSVSVAPA 480 Query: 450 --AQPDPLPPVTGLTVAAEQWHQVAVPEVSGHHRIAVVGLDSECA-------VAGHLRDA 500 + PD T + E+W +++ ++ + +V CA A H A Sbjct: 481 APSVPDATADTTPARLLVEEWVRLSQRSLTPPRVVGIVDPTGACAQLATAMTAAAHQAGA 540 Query: 501 AER-IEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDV 559 R + G A +TL+++ P + D A E+G +P + T T D Sbjct: 541 TARVVNGENDGTGADVNTLVILLPETPKLDGRAAAAEVGGFFSNRAW-WPGVDTGVT-DC 598 Query: 560 WLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDVPMG--LDXXXXXXXX 617 WLVT GE PV AA +A RSI EHPD FR LD+P G Sbjct: 599 WLVTVGGEAATAADGPPDPVHAAASAGFRSIGAEHPDVGFRHLDLPAGATAQDWAHPIVA 658 Query: 618 XXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQF 677 +LA R D A + G A A P + V+I GGTG +GL+ Sbjct: 659 ALHTANEPELAYR-DGAFYAKRIVAGEGAVVHGAGACP------EHVLIIGGTGNLGLES 711 Query: 678 XXXXXXXXXXXXXXXSRNGIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVAAEFG 732 SR+G + L +I RCD+ D V +AA+ Sbjct: 712 CDHFAHRGARRITLVSRSGESAAVAERLAQLRSATAAQIAVTRCDVGDPAAVSRLAAQHR 771 Query: 733 GQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVS 792 A LI+H I VL A+P RI+LCSS Sbjct: 772 STPADLIIHAAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSAR 831 Query: 793 GLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLR 852 NR+LD MA RLR+EG C +V+WG W +DA + ++ G+ Sbjct: 832 ATIGGRGQVMYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVI 891 Query: 853 AMAPDRAVDTALQDFAGDPLV--FSADAQRLAL 883 M P A+ +Q + +V F+ D R L Sbjct: 892 PMPPAEAIALGMQRLGRNAIVAAFNFDRARPVL 924 >tr|B1MPE9|B1MPE9_MYCA9 Tax_Id=561007 SubName: Full=Putative polyketide synthase MbtD;[Mycobacterium abscessus] Length = 1010 Score = 286 bits (732), Expect = 1e-74 Identities = 257/916 (28%), Positives = 370/916 (40%), Gaps = 66/916 (7%) Query: 23 LIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDELTAGLRALADGD 82 ++ +A+A+L Y+ AP+ +A A+ D+L A LR + G Sbjct: 1 MLRREASALLAYVADHPRIAPNRIAGMIFRTRVARRYRALATVENHDQLVAALRTVVAGT 60 Query: 83 DHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY-RLDDYRAEVDRCXXXXXXXXX 141 +HPLV R + +P + RR FVFPGQG Q P MG Y +RAEV+RC Sbjct: 61 EHPLVVRNS--EPATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVERCADLFDKQFG 118 Query: 142 XSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDITVGHSLGEIGA 201 SPL YLL D + TND + V +Q A F V LA +WR+ GV P VGHS GEI Sbjct: 119 RSPLSYLL---DDQLPTNDSATV-VQPALFTQMVGLAALWRTVGVTPRAVVGHSQGEIAG 174 Query: 202 AYVAGAITLPEAVAIVIARATVLDRL-TGPYRVAVLGITPEQAAEVIAETPGWLELXXXX 260 AYV+G ++L +AV +V RA + D Y +AV+ + E++A GW EL Sbjct: 175 AYVSGVMSLDDAVTVVGTRAGIADEFPADDYAMAVIATDRDTCEELLARNSGWAELSVIN 234 Query: 261 XXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRAD----LDALLPAG 316 G+ FA+ I + +PAHT+ + + A L L AG Sbjct: 235 SPSMVGISGQRETVHQIVEHLIEDGVFARVIPVRYPAHTSMIASIGAQIRHALTENLDAG 294 Query: 317 RFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXIFVELSAHP 376 F + + IG+ ++ YW+ NLR VRFD+ FVEL+ HP Sbjct: 295 EFTVSEIDCIGATLGTAISPEMPVDQYWFWNLRNAVRFDRAVATAAAAHVDTFVELAEHP 354 Query: 377 ALLFNMGE---LLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRW---RDQLGD 430 L + E L S R +VG+ R+ N+ +A+ D Y W R + D Sbjct: 355 TLQLALRENLAALGSERTACVVGTSHRNATDLGEFTANLAKIAVHDLDYNWDALRTEAPD 414 Query: 431 CHAV-LPDFPFAPMRAEHLW-------------AQPDPLPPVTGLT-----------VAA 465 ++ L DFP LW QP P + Sbjct: 415 RVSLPLRDFPNVQNNDIPLWLSYRADTSGVAVPKQPIVTPEAERRVEMGNDSRAYPRLLR 474 Query: 466 EQWHQVAVPEVSGHHRIAVV-GLDSECAVAGHLRDAAER-------IEGVEVVAPAAADT 517 E W +V + A + G A+ LRD+A + G + ADT Sbjct: 475 EAWAKVTRRSMMPPRSYAFIDGTGDAGALVEALRDSAPNFGSSARIVTGTDESGIGDADT 534 Query: 518 LLVVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSL 577 +++V P + D A + + R G + L+ T WLVT GE D + Sbjct: 535 VVIVLPSPALLDDHEAADAVARFF--GNRTWWPRLSSTVTGCWLVTVGGEQAIADDGPAH 592 Query: 578 PVGAAVAAMHRSIAFEHPDQNFRQLDVPMGL--DXXXXXXXXXXXXXXXXDLALRCDVAD 635 PV AA+AA R + EHP FR LD+ + +LALR D Sbjct: 593 PVHAAIAAGFRCMGTEHPGIAFRHLDLTSDIASPDKADNILAALQSAGESELALRADGMY 652 Query: 636 GPGTTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRN 695 + ++S AP VVITGGTG +G +F SR+ Sbjct: 653 AKRVLDIDQDGDESSRVVAP------AHVVITGGTGKLGQEFCEHYARMGTRQITLISRS 706 Query: 696 G---IEGNRVDEL--PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXX 750 G R+D + G ++ A CD+TD V +A + A LIVH Sbjct: 707 GETDAVTGRLDAIRRSTGAKVRALPCDVTDTAAVTALADQLRDTPADLIVHAAVDYSDTP 766 Query: 751 XXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLL 810 I NVL P R++LCSS++ NR+L Sbjct: 767 LSEVTTNKFQDALRAKVIGISNVLDTVPRTDSCRVMLCSSLAATIGGKGQLMYAAGNRML 826 Query: 811 DVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGD 870 DV+A R+ G CT+++WG W + I ++ +G+ M P A+ + G+ Sbjct: 827 DVLASTRRASGLDCTSIQWGQWTVHLDLGDAGIAKLAAAGVHPMRPADALAVGMGHHHGN 886 Query: 871 PLVFSADAQRLALFLG 886 LV + D + LG Sbjct: 887 TLVGAFDLTQARAMLG 902 >tr|Q9F828|Q9F828_9ACTO Tax_Id=136926 (megAIII)SubName: Full=Megalomicin 6-deoxyerythronolide B synthase 3;[Micromonospora megalomicea subsp. nigra] Length = 3201 Score = 232 bits (591), Expect = 2e-58 Identities = 276/984 (28%), Positives = 381/984 (38%), Gaps = 113/984 (11%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPS--DVAYXXXXXXXXXXXXAVIRAGGLD 69 V +V SA E + A + L D APS D A+ AV+ GG + Sbjct: 488 VALVFSARDERALRAQAARLADRLTD--DPAPSLRDTAFTLVTRRATWEHRAVVVGGG-E 544 Query: 70 ELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAE- 128 E+ AGLRA+A G V A + + + RRV VFPGQG+QW M + R AE Sbjct: 545 EVLAGLRAVAGGRP---VDGAVSGRARAGRRVVLVFPGQGAQWQGMARDLLRQSPTFAES 601 Query: 129 VDRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVP 188 +D C +D+ L G + D V +Q F V+LAR+W+S+GV P Sbjct: 602 IDACERALAPH-----VDWSLREVLDGEQSLDPVDV-VQPVLFAVMVSLARLWQSYGVTP 655 Query: 189 DITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIA 248 VGHS GEI AA+VAGA++L +A +V R+ VL RL G +A G+ P+QAAE IA Sbjct: 656 GAVVGHSQGEIAAAHVAGALSLADAARVVALRSRVLRRLGGHGGMASFGLHPDQAAERIA 715 Query: 249 ETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRAD 308 G L + GE A+ I + + +H+ ++ +R + Sbjct: 716 RFAGALTVASVNGPRSVVLAGENGPLDELIAECEAEGVTARRIPVDYASHSPQVESLREE 775 Query: 309 LDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXI 368 L A L R + + T V+ T T ADYW+ NLR VRF Sbjct: 776 LLAALAGVRPVSAGIPLYSTLTGQVIETATMDADYWFANLREPVRFQDATRQLAEAGFDA 835 Query: 369 FVELSAHPALLFNMGELLEST----RGVVLVGSGRRDEPLPERLADNVITVALADAGYR- 423 FVE+S HP L + LE+ + G+ RR ER ALA+A R Sbjct: 836 FVEVSPHPVLTVGVEATLEAVLPPDADPCVTGTLRR-----ERGGLAQFHTALAEAYTRG 890 Query: 424 ----WRDQLGDCHAVLPDFPFAPMRAEHLWAQPDPL--PPVTGLTVAAE-QWHQVAVPEV 476 WR +G+ V D P P + ++ W P PL P TG + WH V + Sbjct: 891 VEVDWRTAVGEGRPV--DLPVYPFQRQNFWL-PVPLGRVPDTGDEWRYQLAWHPVDLGRS 947 Query: 477 SGHHRIAVV---------------GLDSE------CAVAGHLRDAAERIEGVEVVAPAAA 515 S R+ VV GL+ C R A ++ V+ A + Sbjct: 948 SLAGRVLVVTGAAVPPAWTDVVRDGLEQRGATVVLCTAQSRARIGA-ALDAVDGTALSTV 1006 Query: 516 DTLLVVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDG 575 +LL +A + +DP L L + + + P +WLVT V V D Sbjct: 1007 VSLLALAEGGAVDDPSLDTLALVQALGAAGIDVP---------LWLVTRDAAAVTVGDDV 1057 Query: 576 SLPVGAAVAAMHRSIAFEHPDQ-----NFRQLDVPMGLDXXXXXXXXXXXXXXXXDLALR 630 P A V + R + E P + + R+ D D A+R Sbjct: 1058 D-PAQAMVGGLGRVVGVESPARWGGLVDLREADA----DSARSLAAILADPRGEEQFAIR 1112 Query: 631 CDVADGPGTTLWRRGMRDASAAAAPW-PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXX 689 D G T+ R A AA W P G V++TGGTG +G Sbjct: 1113 PD-----GVTVARLVPAPARAAGTRWTPRGT---VLVTGGTGGIGAHLARWLAGAGAEHL 1164 Query: 690 XXXSRNGIEGN-----RVDELPLGVEIVAPRCDLTDIPRVRDV--AAEFGGQGASLIVHX 742 +R G E R + + LG + CD+ D R+ V AA G+ + + H Sbjct: 1165 VLLNRRGAEAAGAADLRDELVALGTGVTITACDVADRDRLAAVLDAARAQGRVVTAVFHA 1224 Query: 743 XXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXX 802 N+ P DA ++L SS + +W Sbjct: 1225 AGISRSTAVQELTESEFTEITDAKVRGTANLAELCP-ELDA-LVLFSSNAAVWGSPGLAS 1282 Query: 803 XXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVD- 861 N LD A R R G T++ WGLW G + + + GLRAM P RA++ Sbjct: 1283 YAAGNAFLDAFARRGRRSGLPVTSIAWGLWAGQNMAGTEGGDYLRSQGLRAMDPQRAIEE 1342 Query: 862 --TALQDFAGDPLVFSADAQR---LALFLGT------DADTGTGREATHAAQHRD----- 905 T L AGDP V D R + LF D G A Q D Sbjct: 1343 LRTTLD--AGDPWVSVVDLDRERFVELFTAARRRPLFDELGGVRAGAEETGQESDLARRL 1400 Query: 906 AGPPADAEHHDTGAAVRIALAAVL 929 A P H VR +AAVL Sbjct: 1401 ASMPEAERHEHVARLVRAEVAAVL 1424 Score = 200 bits (509), Expect = 8e-49 Identities = 248/877 (28%), Positives = 338/877 (38%), Gaps = 81/877 (9%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDT-APSDVAYXXXXXXXXXXXXAVIRAGGLDE 70 VPVVLSA E + A R D DT A VA A + A DE Sbjct: 1960 VPVVLSAKTETALTELAR---RLHDAVDDTVALPAVAATLATGRAHLPYRAALLARDHDE 2016 Query: 71 LTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAEVD 130 L LRA G P V A G V FVFPGQG QW M + + V Sbjct: 2017 LRDRLRAFTTGSAAPGVVSGVASGGG----VVFVFPGQGGQWVGMARGLLSVPVFVESVV 2072 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDI 190 C S L L SG + D V +Q FV V+LAR+WR GVVP Sbjct: 2073 ECDAVVSSVVGFSVLGVLEGR--SGAPSLDRVDV-VQPVLFVVMVSLARLWRWCGVVPAA 2129 Query: 191 TVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAET 250 VGHS GEI AA VAG +++ + +V RA L L G + L ++ E+A E+IA Sbjct: 2130 VVGHSQGEIAAAVVAGVLSVGDGARVVALRARALRALAGHGGMVSLAVSAERARELIAPW 2189 Query: 251 PGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADLD 310 + + G+ AK + + + +H+ ++ +R D Sbjct: 2190 SDRISVAAVNSPTSVVVSGDPQALAALVAHCAETGERAKTLPVDYASHSAHVEQIR---D 2246 Query: 311 ALLP--AGRFAETPVQFIGSATADVVTTGTDF-ADYWYTNLRTTVRFDQXXXXXXXXXXX 367 +L A A P + S GTD A YWY NLR+ VRFD+ Sbjct: 2247 TILTDLADVTARRPDVALYSTLHGARGAGTDMDARYWYDNLRSPVRFDEAVEAAVADGYR 2306 Query: 368 IFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQ 427 +FVE+S HP L + E+ + T V +GS RD L + + WR Sbjct: 2307 VFVEMSPHPVLTAAVQEIDDET---VAIGSLHRDTG-ERHLVAELARAHVHGVPVDWRAI 2362 Query: 428 LGDCHAV-LPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVP--EVSGHHRI-- 482 L H V LP++PF A W P V + W +A E+SG + + Sbjct: 2363 LPATHPVPLPNYPF---EATRYWLAPTAADQVADHRYRVD-WRPLATTPAELSGSYLVFG 2418 Query: 483 ---AVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGR 539 +G E A + AA E + V AA L V ++ LA L Sbjct: 2419 DAPETLGHSVEKAGGLLVPVAAPDRESLAVALDEAAGRLAGVLSFAADTATHLARHRL-- 2476 Query: 540 RIDEGLLRYPDLLTETTRDVWLVTGRG----EHVPVDRDGSLPVGAAVAAMHRSIAFEHP 595 + E + P +WLVT G +H P+D D ++ G R + E P Sbjct: 2477 -LGEADVEAP---------LWLVTSGGVALDDHDPIDCDQAMVWGIG-----RVMGLETP 2521 Query: 596 DQNFRQLDVPMG--LDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMR-DASAA 652 + +DV + + +ALR + G RR +R + Sbjct: 2522 HRWGGLVDVTVEPTAEDGVVFAALLAADDHEDQVALRDGIRHG------RRLVRAPLTTR 2575 Query: 653 AAPW-PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDELP----- 706 A W P G ++TGGTGA+G SR+G + EL Sbjct: 2576 NARWTPAGT---ALVTGGTGALGGHVARYLARSGVTDLVLLSRSGPDAPGAAELAAELAD 2632 Query: 707 LGVEIVAPRCDLTDIPRVRDVAAEFGGQG--ASLIVHXXXXXXXXXXXXXXXXXXXXXXX 764 LG E CD+TD PR+R + E Q ++VH Sbjct: 2633 LGAEPRVEACDVTDGPRLRALVQELREQDRPVRIVVHTAGVPDSRPLDRIDELESVSAAK 2692 Query: 765 XXXXXIENVLAAWPVRPDA-RILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + + L PDA +L SS +G+W N LD +A R R GR Sbjct: 2693 VTGARLLDELC-----PDADTFVLFSSGAGVWGSANLGAYAAANAYLDALAHRRRQAGRA 2747 Query: 824 CTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAV 860 T+V WG W G G+ D + + R GLRAMAPDRA+ Sbjct: 2748 ATSVAWGAWAGDGMATGD-LDGLTRRGLRAMAPDRAL 2783 >tr|Q83X69|Q83X69_STRRO Tax_Id=1928 (lkmAI)SubName: Full=Lankamycin synthase LkmAI;[Streptomyces rochei] Length = 3651 Score = 230 bits (587), Expect = 7e-58 Identities = 266/990 (26%), Positives = 370/990 (37%), Gaps = 108/990 (10%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 VP+V+SA E +A + + +L DT D A AV A G+ + Sbjct: 2542 VPLVVSARTETALAAQSRRLAEHLTQHQDTVLRDAAGTLTGARQHFDRRAVALARGVADA 2601 Query: 72 TAGLRALADGDDHP-LVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAEVD 130 T LRALA+G P LVT G RRV +VFPGQGSQW MG + + + Sbjct: 2602 TGTLRALAEGLPAPGLVTGVG----GGGRRVVWVFPGQGSQWVGMGRGLLDVPVFAQALA 2657 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDI 190 C S +D + G D +V +Q F V+LAR+WR+ GV PD Sbjct: 2658 ECDAALAEVAGFSVVD--VVRGVEGAPGLDRVEV-VQPVLFAVMVSLARLWRACGVEPDA 2714 Query: 191 TVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAET 250 VGHS GEI AA VAGA++LP+A +V RA L L GP + L A E++ Sbjct: 2715 VVGHSQGEIAAACVAGALSLPDAARVVALRAQALAELAGPGAMMSLRTGRASAEELLGGA 2774 Query: 251 PGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADLD 310 PG EL G+ A+ + + + +HT+ ++ +R + Sbjct: 2775 PGAPELATVNGPGAVVVAGDPEAVRGFRDTCAAAGVDARILPVDYASHTSHMEPLRDAVT 2834 Query: 311 ALLPAGRFAETPVQFIGSATADVVTTGTDF-ADYWYTNLRTTVRFDQXXXXXXXXXXXIF 369 A L +G TP + S G + A YW+ NLR TV F+ +F Sbjct: 2835 APL-SGIVPRTPAVPLYSTLRGAFVEGPELDAGYWFDNLRHTVEFEAAVEALAAAGHDVF 2893 Query: 370 VELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQLG 429 VE+S HP L +M + L T V +GS +RD+ PER + + WR LG Sbjct: 2894 VEVSPHPVLNGSMQDTLGDTSAV--LGSVQRDDDTPERFLSALAEAHVNGVTVDWRTVLG 2951 Query: 430 DCH-AVLPDFPFAPMRAEHLWAQPDP---------------------------------- 454 D A LP +PF R W PD Sbjct: 2952 DAEPADLPTYPFEHQR---YWLMPDATGPSRPDAGWRYRIGWQETAVTDASAGPAGRWLL 3008 Query: 455 -LPPVTGLTVAAEQWHQVAVPEVSGH----HRIAVVGLDSECAVAGHLRDAAERIEGVEV 509 LP +G W++ A ++ H H + V LD A+ +RDA E Sbjct: 3009 LLPAPSGTGPGRPVWYEAAATALAEHGARPHPV-TVPLDDPQALTTAVRDAL----ATEA 3063 Query: 510 VAPAAADTLLVVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHV 569 + A A L ++A L + G GLLR + VWL T Sbjct: 3064 ASGAYAGVLSLLA---------LDDADTGAEATLGLLR-ELAAADADTPVWLATCGAVGT 3113 Query: 570 PVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDVPMGLDXXXXXXXXXXXXXXXXDLAL 629 D + P GA V + ++ A E ++ +D+P LA+ Sbjct: 3114 GADDPVTCPAGAQVWGLGQAAALERGARHTGLVDLPPEATETQRALFARALTGTEDQLAI 3173 Query: 630 RCDVADGPGTTLWRRGMRDASAA-AAPWPTGVL---DDVVITGGTGAVGLQFXXXXXXXX 685 R L RR + A A P P L +++TGGTG +G Sbjct: 3174 RAQ------AVLARRLLPAAPGADRMPAPADGLVPQGTILVTGGTGGLGALTARRLAARG 3227 Query: 686 XXXXXXXSRNGIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASL-- 738 SR G V EL LG + CD++ +V + GA++ Sbjct: 3228 AQHLALVSRRGAAAPGVPELVAELTGLGARVTVHACDVSVPEQVAALTGGLRADGATITG 3287 Query: 739 IVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXX 798 +VH N+ A P + LL SS + +W Sbjct: 3288 VVHAAGVNQQSAVREMTREEFRTVLAAKVDGARNLAHACPGL--SLFLLFSSGAAVWGSA 3345 Query: 799 XXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGII-DADEITRVERSGLRAMAPD 857 N LD A+ R+ G T+V WGLW G+ DA + R+ G+R M + Sbjct: 3346 GQGAYAAGNAFLDAFAQHRRARGLAATSVAWGLWAEGGMTDDAQAVARLRDQGVRPMPGE 3405 Query: 858 RAVDTALQDFAG-DPLVFSAD-----------AQRLALFLGTDADTGTGR----EATHAA 901 RA+D AG + V AD A R L T E A Sbjct: 3406 RALDALETVLAGAETAVVVADVDWPRFTETYTALRARPLLDTVPSARPAAPARPEPAAGA 3465 Query: 902 QHRD--AGPPADAEHHDTGAAVRIALAAVL 929 RD AG P +H + VR AAVL Sbjct: 3466 TLRDRLAGRPRSEQHQELTRLVRSHAAAVL 3495 Score = 224 bits (570), Expect = 7e-56 Identities = 257/964 (26%), Positives = 356/964 (36%), Gaps = 88/964 (9%) Query: 13 PVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDELT 72 P V+SAH+E + A + +L + P+DVA+ A GG D Sbjct: 1040 PWVVSAHSEAALRDQAGRLAAHLHEQPGHTPADVAFSLATTRAAARHRAAFVPGGYDAAL 1099 Query: 73 AGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAE-VDR 131 L LA G +VT A P FVFPGQG QW M V Y A +D Sbjct: 1100 DALDELAGGGTEGVVTGTARPGASP----VFVFPGQGWQWAGMAVALYDSSPVFARALDE 1155 Query: 132 CXXXXXXXXXXSPLDYLLAH-------PDSGVSTNDFSQVQIQGAQFVHGVALARVWRSH 184 C S L +L A PD+ +S++ VQ F V+LA +WR+H Sbjct: 1156 CAAALRPHLDFSVLPFLRAEAAAAAGRPDADLSSDRVDVVQ--PVLFAVMVSLAALWRAH 1213 Query: 185 GVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAA 244 GV P +GHS GEI AA VAGA++L +A +V R+ V+ + G +A + +T A Sbjct: 1214 GVEPAAVIGHSQGEIAAACVAGALSLDDAARLVAVRSRVIAGMRGGGGMAAVAVTAADLA 1273 Query: 245 EVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDG 304 E IA G LE G A+ + + + +HT +D Sbjct: 1274 ERIARYDGRLETAALNGPRSVVVAGPDDDLDHLLAALGAEGVRARRLPVDYASHTAHMDD 1333 Query: 305 VR-------ADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQX 357 R AD++ LP G V F + T D YW+ NLR TVR + Sbjct: 1334 ARTALHEELADIEP-LPGG-----AVPFYSTVTGDWAAPAALDGAYWFRNLRETVRLEPA 1387 Query: 358 XXXXXXXXXXIFVELSAHPALLFNMGEL-LESTRGVVLVGSGRRDEPLPERLADNVITVA 416 F+E+SAHP L + E ++ + VG+ RR + E A + T Sbjct: 1388 VRALTEQGYRTFIEVSAHPVLTTAIEETGQDAGADLAAVGTLRRGQGGAEDFAHALATAW 1447 Query: 417 LADAGYRWRDQ-LGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTV--AAE------Q 467 A RW LG +P P AP + E W +P P T AA+ Sbjct: 1448 AAGVPVRWESVFLGTAARAVP-LPTAPFQRERHWLEPAPQATAPSGTAHDAADALRYRID 1506 Query: 468 WHQVAVPE--VSGHHRIAVVGLDSECAVAGHLRDAAERIEGVEVV------APA------ 513 W +++ PE +G R +V D A AA + G V APA Sbjct: 1507 WQRISAPEPAATGPRRWLLVRYDGAAEPAARAARAALEVAGATVTDLVVAGAPAPDALAL 1566 Query: 514 -------AADTLLVVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRD--VWLVTG 564 AD + V++ + + A LG G + L + D +W +T Sbjct: 1567 ELLRAAEGADRIGVLSLLAVDERGEGAATPLGLPSLGGTVALARALAGSGLDGLLWCLTE 1626 Query: 565 RGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDVPMG--LDXXXXXXXXXXXXX 622 + D P A+ + R IA EHP +DVP G + Sbjct: 1627 DVQVTSADERPGDPAREALWGLGRVIALEHPGLWGGLIDVPAGSTAELTRSLAGVLTGGS 1686 Query: 623 XXXDLALRCDVADGPGTTLWRRGMRDA-SAAAAPW-PTGVLDDVVITGGTGAVGLQFXXX 680 LALR P RR R A A W PTG ++TGGTG +G Sbjct: 1687 GEDQLALR------PAGVFARRWKRAAPRTAPGGWEPTGT---ALVTGGTGGIGRNVARW 1737 Query: 681 XXXXXXXXXXXXSRNGIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVAAEF-GGQ 734 SR+G E EL LG + CD+TD +R + A Q Sbjct: 1738 LAQHGAPHIVLVSRSGPEAPGAGELAAELRALGSAVTLAACDVTDREALRSLLAALPADQ 1797 Query: 735 GASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGL 794 + + H N+ P +L SS + Sbjct: 1798 PLTSVFHTAATLDDGTLDTLTGERIEQAGRAKTLGARNLHELTADAPLTAFVLFSSFASA 1857 Query: 795 WXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAM 854 + N LD +A R R++G T+V WG W G+G+ + R R G+ M Sbjct: 1858 FGAPGLGCYAPGNAYLDGLARRRRADGLPATSVAWGTWAGSGMAEGPVAERFRRHGVVEM 1917 Query: 855 APDRAVD---TALQDFAGDPLVFSADAQRLALFLGTDADT---GTGREATHA--AQHRDA 906 A A+D TAL P++ D +R L T EA HA A R Sbjct: 1918 AAPEALDALRTALDRAEVCPVIIGVDWERFLLAYTAQRPTRLFDALPEARHAHEALRRAH 1977 Query: 907 GPPA 910 G PA Sbjct: 1978 GAPA 1981 Score = 127 bits (320), Expect = 7e-27 Identities = 160/572 (27%), Positives = 221/572 (38%), Gaps = 42/572 (7%) Query: 13 PVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDELT 72 P VLSA + + A +L +L ++ V AVI E+ Sbjct: 21 PWVLSAADDRALRVWARRLLDHLRAHPESGADGVGAALAHQDRRLPRRAVIVGSSRAEIL 80 Query: 73 AGLRALADGDDHPLVTR--AAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAE-V 129 GL A+AD HP V R AAAP P V FVFPGQGSQWP M E A+ + Sbjct: 81 DGLAAVADDRPHPAVARGTAAAPAP-----VTFVFPGQGSQWPGMATELLGESAVFADAI 135 Query: 130 DRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQI-QGAQFVHGVALARVWRSHGVVP 188 +RC S + L ++ + +V+I Q A + AL +WRS GV P Sbjct: 136 ERCAQVFAAESGWSLTEAL----ETAAAPGTVPRVEIVQPALYAVSAALTELWRSFGVEP 191 Query: 189 DITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIA 248 D VGHS+G++ AA+ AGA+T+ + V + L L G +A + + + A +A Sbjct: 192 DAVVGHSMGDLAAAHAAGAVTIEDGARAVARWSKELRPLVGKGDMASVELPADLVAPRLA 251 Query: 249 ETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRAD 308 + L L G A+ I + AH+ +D V A Sbjct: 252 DWGPDLVLAGINGPRSVLLAGATDAIERCVAELTAEGVRARTIGVSMAAHSPHMDWVVAR 311 Query: 309 LDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXI 368 + A L V S T V+ T A++W N R V F++ + Sbjct: 312 VRAALDWFTPGAGAVPLYSSRTGAVLDTRELTAEHWCANFRGRVEFERSVRDCTAERGGV 371 Query: 369 FVELSAHPALLFNMGELLESTRG--VVLVGSGRRDEPLPERLADNVITVALADAGYRWRD 426 F+ELS HP L + + L++ VL R L LA + W Sbjct: 372 FLELSPHPVLAAAVRQTLDAAGSGHPVLATLRRGQGGLRRFLAADGRQPYTNGVDIDWSA 431 Query: 427 QLGDC----HAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGH--- 479 A LPD P A A+ L A DP P G+ AA Q+ P H Sbjct: 432 AFPGAGPATDAGLPDLPEA--GADLLDAGADPAEP--GVRAAAPTRPQLCPPGTPEHEVR 487 Query: 480 HRIAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGR 539 R+A + AV G A+ +G A D++L V D + A LGR Sbjct: 488 QRLAGLVHAETAAVTG-----AQAADGSLTFAELGIDSVLAV----QLRDRLAAA--LGR 536 Query: 540 RIDEGLL---RYPDLLTETTRDVWLVTGRGEH 568 I L P LTE D L+ R EH Sbjct: 537 DIAIATLFDHPTPQALTEALYD--LIGPRAEH 566 >tr|A4F7P1|A4F7P1_SACEN Tax_Id=405948 (eryAIII)SubName: Full=EryAIII Erythromycin polyketide synthase modules 5 and 6;[Saccharopolyspora erythraea] Length = 3171 Score = 224 bits (571), Expect = 5e-56 Identities = 268/965 (27%), Positives = 367/965 (38%), Gaps = 98/965 (10%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 VP+VLS E + A + +L + D + AV+ G D+ Sbjct: 468 VPLVLSGRDEQAMRAQAGRLADHLAREPRNSLRDTGFTLATRRSAWEHRAVV-VGDRDDA 526 Query: 72 TAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAEVDR 131 AGLRA+ADG + R A Q +RR VA VFPGQG+QW M + R A+ R Sbjct: 527 LAGLRAVADGR---IADRTATGQARTRRGVAMVFPGQGAQWQGMARDLLRESQVFADSIR 583 Query: 132 -CXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDI 190 C S D L SG D V +Q A F V+LA +WRSHGV P Sbjct: 584 DCERALAPHVDWSLTDLL-----SGARPLDRVDV-VQPALFAVMVSLAALWRSHGVEPAA 637 Query: 191 TVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAET 250 VGHS GEI AA+VAGA+TL +A +V R+ VL RL G +A G+ EQAAE I Sbjct: 638 VVGHSQGEIAAAHVAGALTLEDAAKLVAVRSRVLRRLGGQGGMASFGLGTEQAAERIGRF 697 Query: 251 PGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADLD 310 G L + GE A+ I + + +H+ ++ +R +L Sbjct: 698 AGALSIASVNGPRSVVVAGESGPLDELIAECEAEGITARRIPVDYASHSPQVESLREELL 757 Query: 311 ALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXIFV 370 L V + T + T T YWY NLR VRF FV Sbjct: 758 TELAGISPVSADVALYSTTTGQPIDTATMDTAYWYANLREQVRFQDATRQLAEAGFDAFV 817 Query: 371 ELSAHPALLFNMGELLEST----RGVVLVGSGRRDEPLPERLADNVITVALADAGYR--- 423 E+S HP L + L+S G +VG+ RRD LAD AL +A + Sbjct: 818 EVSPHPVLTVGIEATLDSALPADAGACVVGTLRRDR---GGLAD--FHTALGEAYAQGVE 872 Query: 424 --WRDQLGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQ--------WHQVAV 473 W D V + P P + + W LP TG E W + Sbjct: 873 VDWSPAFADARPV--ELPVYPFQRQRYW-----LPIPTGGRARDEDDDWRYQVVWREAEW 925 Query: 474 PEVSGHHRIAVV---GLDSEC--AVAGHLRDAAERIEGVEV-------VAPAAADT--LL 519 S R+ +V G+ SE A+ L + + +V A AADT L Sbjct: 926 ESASLAGRVLLVTGPGVPSELSDAIRSGLEQSGATVLTCDVESRSTIGTALEAADTDALS 985 Query: 520 VVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSL-- 577 V ++S + GE + +D L +W++T V DG L Sbjct: 986 TVVSLLSRD-----GEAVDPSLDALALVQALGAAGVEAPLWVLTRNAVQV---ADGELVD 1037 Query: 578 PVGAAVAAMHRSIAFEHPDQNFRQLD-VPMGLDXXXXXXXXXXXXXXXXDLALRCDVADG 636 P A V + R + E P + +D V +A+R D Sbjct: 1038 PAQAMVGGLGRVVGIEQPGRWGGLVDLVDADAASIRSLAAVLADPRGEEQVAIRAD---- 1093 Query: 637 PGTTLWRRGMRDASAAAAPW-PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRN 695 G + R A AA W P G V++TGGTG +G R Sbjct: 1094 -GIKVARLVPAPARAARTRWSPRGT---VLVTGGTGGIGAHVARWLARSGAEHLVLLGRR 1149 Query: 696 GIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVAAEFGGQG--ASLIVHXXXXXXX 748 G + EL LG + CD+ D R+ V A +G S ++H Sbjct: 1150 GADAPGASELREELTALGTGVTIAACDVADRARLEAVLAAERAEGRTVSAVMHAAGVSTS 1209 Query: 749 XXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNR 808 N+ P DA +L SS +G+W N Sbjct: 1210 TPLDDLTEAEFTEIADVKVRGTVNLDELCP-DLDAFVLF-SSNAGVWGSPGLASYAAANA 1267 Query: 809 LLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFA 868 LD A R RSEG T++ WGLW G + + + GLRAM PDRAV Sbjct: 1268 FLDGFARRRRSEGAPVTSIAWGLWAGQNMAGDEGGEYLRSQGLRAMDPDRAV-------- 1319 Query: 869 GDPLVFSADAQRLALFLGTDADTGTGREATHAAQHRD-----AGPPADAEHHDTGAAVRI 923 + L + D + ++ + D D E AA+HR AG A+A + G A+ Sbjct: 1320 -EELHITLDHGQTSVSV-VDMDRRRFVELFTAARHRPLFDEIAGARAEARQSEEGPALAQ 1377 Query: 924 ALAAV 928 LAA+ Sbjct: 1378 RLAAL 1382 Score = 203 bits (517), Expect = 9e-50 Identities = 238/895 (26%), Positives = 346/895 (38%), Gaps = 82/895 (9%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAP-SDVAYXXXXXXXXXXXXAVIRAGGLDE 70 VPV+LSA E +A A + +D D+ P + +A A + AG ++ Sbjct: 1933 VPVLLSARTETALAAQARLLESAVD---DSVPLTALASALATGRAHLPRRAALLAGDHEQ 1989 Query: 71 LTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAEVD 130 L LRA+A+G P T A G V FVFPGQG+QW M + + + Sbjct: 1990 LRGQLRAVAEGVAAPGATTGTASAGG----VVFVFPGQGAQWEGMARGLLSVPVFAESIA 2045 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQI-QGAQFVHGVALARVWRSHGVVPD 189 C S + L PD+ +V + Q F V+LAR+W + GV P Sbjct: 2046 ECDAVLSEVAGFSASEVLEQRPDAP----SLERVDVVQPVLFSVMVSLARLWGACGVSPS 2101 Query: 190 ITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAE 249 +GHS GEI AA VAG ++L + V +V RA L L G + L E+A +IA Sbjct: 2102 AVIGHSQGEIAAAVVAGVLSLEDGVRVVALRAKALRALAGKGGMVSLAAPGERARALIAP 2161 Query: 250 TPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVR--- 306 + + G+ AK + + + +H+ ++ +R Sbjct: 2162 WEDRISVAAVNSPSSVVVSGDPEALAELVARCEDEGVRAKTLPVDYASHSRHVEEIRETI 2221 Query: 307 -ADLDALLPAGRFAETPVQFIGSATADVVTTGTDFAD-YWYTNLRTTVRFDQXXXXXXXX 364 ADLD + + R A P+ S G D YWY NLR+ VRFD+ Sbjct: 2222 LADLDGI--SARRAAIPLY---STLHGERRDGADMGPRYWYDNLRSQVRFDEAVSAAVAD 2276 Query: 365 XXXIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRW 424 FVE+S HP L + E+ V +GS RD E L + + W Sbjct: 2277 GHATFVEMSPHPVLTAAVQEI---AADAVAIGSLHRD-TAEEHLIAELARAHVHGVAVDW 2332 Query: 425 RDQLGDCHAV-LPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHHRIA 483 R+ V LP++PF P R W P+ + + W +A V Sbjct: 2333 RNVFPAAPPVALPNYPFEPQR---YWLAPEVSDQLADSRYRVD-WRPLATTPVDLEGGFL 2388 Query: 484 VVGLDSECAVAGHLRDAAERIEGV-----EVVAPAAADTLLVVAPMISENDPVLAGEELG 538 V G E ++ + A R+ V E +A A + VA ++S + L Sbjct: 2389 VHGSAPE-SLTSAVEKAGGRVVPVASADREALAAALREVPGEVAGVLSVHTGAATHLALH 2447 Query: 539 RRIDEGLLRYPDLLTETTRDVWLVTGR----GEHVPVDRDGSLPVGAAVAAMHRSIAFEH 594 + + E +R P +WLVT R GE PVD P A V + R + E Sbjct: 2448 QSLGEAGVRAP---------LWLVTSRAVALGESEPVD-----PEQAMVWGLGRVMGLET 2493 Query: 595 PDQNFRQLDVPM--GLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAA 652 P++ +D+P +A+R G G R++S Sbjct: 2494 PERWGGLVDLPAEPAPGDGEAFVACLGADGHEDQVAIRDHARYGRRLVRAPLGTRESS-- 2551 Query: 653 AAPW-PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL-----P 706 W P G ++TGGTGA+G SR G++ EL Sbjct: 2552 ---WEPAGT---ALVTGGTGALGGHVARHLARCGVEDLVLVSRRGVDAPGAAELEAELVA 2605 Query: 707 LGVEIVAPRCDLTDIPRVRDVAAEFGGQGASL--IVHXXXXXXXXXXXXXXXXXXXXXXX 764 LG + CD+ D ++ + E GQG + +VH Sbjct: 2606 LGAKTTITACDVADREQLSKLLEELRGQGRPVRTVVHTAGVPESRPLHEIGELESVCAAK 2665 Query: 765 XXXXXIENVLAAWPVRPDAR-ILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + + L PDA +L SS +G+W N LD +A R R+EGR Sbjct: 2666 VTGARLLDELC-----PDAETFVLFSSGAGVWGSANLGAYSAANAYLDALAHRRRAEGRA 2720 Query: 824 CTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDF-AGDPLVFSAD 877 T+V WG W G G+ D + + R GLR MAP+RA+ Q GD V AD Sbjct: 2721 ATSVAWGAWAGEGMATGD-LEGLTRRGLRPMAPERAIRALHQALDNGDTCVSIAD 2774 >tr|Q5UNP4|Q5UNP4_SACER Tax_Id=1836 (eryAIII)SubName: Full=EryAIII;[Saccharopolyspora erythraea] Length = 3171 Score = 224 bits (571), Expect = 5e-56 Identities = 268/965 (27%), Positives = 367/965 (38%), Gaps = 98/965 (10%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 VP+VLS E + A + +L + D + AV+ G D+ Sbjct: 468 VPLVLSGRDEQAMRAQAGRLADHLAREPRNSLRDTGFTLATRRSAWEHRAVV-VGDRDDA 526 Query: 72 TAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAEVDR 131 AGLRA+ADG + R A Q +RR VA VFPGQG+QW M + R A+ R Sbjct: 527 LAGLRAVADGR---IADRTATGQARTRRGVAMVFPGQGAQWQGMARDLLRESQVFADSIR 583 Query: 132 -CXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDI 190 C S D L SG D V +Q A F V+LA +WRSHGV P Sbjct: 584 DCERALAPHVDWSLTDLL-----SGARPLDRVDV-VQPALFAVMVSLAALWRSHGVEPAA 637 Query: 191 TVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAET 250 VGHS GEI AA+VAGA+TL +A +V R+ VL RL G +A G+ EQAAE I Sbjct: 638 VVGHSQGEIAAAHVAGALTLEDAAKLVAVRSRVLRRLGGQGGMASFGLGTEQAAERIGRF 697 Query: 251 PGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADLD 310 G L + GE A+ I + + +H+ ++ +R +L Sbjct: 698 AGALSIASVNGPRSVVVAGESGPLDELIAECEAEGITARRIPVDYASHSPQVESLREELL 757 Query: 311 ALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXIFV 370 L V + T + T T YWY NLR VRF FV Sbjct: 758 TELAGISPVSADVALYSTTTGQPIDTATMDTAYWYANLREQVRFQDATRQLAEAGFDAFV 817 Query: 371 ELSAHPALLFNMGELLEST----RGVVLVGSGRRDEPLPERLADNVITVALADAGYR--- 423 E+S HP L + L+S G +VG+ RRD LAD AL +A + Sbjct: 818 EVSPHPVLTVGIEATLDSALPADAGACVVGTLRRDR---GGLAD--FHTALGEAYAQGVE 872 Query: 424 --WRDQLGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQ--------WHQVAV 473 W D V + P P + + W LP TG E W + Sbjct: 873 VDWSPAFADARPV--ELPVYPFQRQRYW-----LPIPTGGRARDEDDDWRYQVVWREAEW 925 Query: 474 PEVSGHHRIAVV---GLDSEC--AVAGHLRDAAERIEGVEV-------VAPAAADT--LL 519 S R+ +V G+ SE A+ L + + +V A AADT L Sbjct: 926 ESASLAGRVLLVTGPGVPSELSDAIRSGLEQSGATVLTCDVESRSTIGTALEAADTDALS 985 Query: 520 VVAPMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSL-- 577 V ++S + GE + +D L +W++T V DG L Sbjct: 986 TVVSLLSRD-----GEAVDPSLDALALVQALGAAGVEAPLWVLTRNAVQV---ADGELVD 1037 Query: 578 PVGAAVAAMHRSIAFEHPDQNFRQLD-VPMGLDXXXXXXXXXXXXXXXXDLALRCDVADG 636 P A V + R + E P + +D V +A+R D Sbjct: 1038 PAQAMVGGLGRVVGIEQPGRWGGLVDLVDADAASIRSLAAVLADPRGEEQVAIRAD---- 1093 Query: 637 PGTTLWRRGMRDASAAAAPW-PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRN 695 G + R A AA W P G V++TGGTG +G R Sbjct: 1094 -GIKVARLVPAPARAARTRWSPRGT---VLVTGGTGGIGAHVARWLARSGAEHLVLLGRR 1149 Query: 696 GIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVAAEFGGQG--ASLIVHXXXXXXX 748 G + EL LG + CD+ D R+ V A +G S ++H Sbjct: 1150 GADAPGASELREELTALGTGVTIAACDVADRARLEAVLAAERAEGRTVSAVMHAAGVSTS 1209 Query: 749 XXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNR 808 N+ P DA +L SS +G+W N Sbjct: 1210 TPLDDLTEAEFTEIADVKVRGTVNLDELCP-DLDAFVLF-SSNAGVWGSPGLASYAAANA 1267 Query: 809 LLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFA 868 LD A R RSEG T++ WGLW G + + + GLRAM PDRAV Sbjct: 1268 FLDGFARRRRSEGAPVTSIAWGLWAGQNMAGDEGGEYLRSQGLRAMDPDRAV-------- 1319 Query: 869 GDPLVFSADAQRLALFLGTDADTGTGREATHAAQHRD-----AGPPADAEHHDTGAAVRI 923 + L + D + ++ + D D E AA+HR AG A+A + G A+ Sbjct: 1320 -EELHITLDHGQTSVSV-VDMDRRRFVELFTAARHRPLFDEIAGARAEARQSEEGPALAQ 1377 Query: 924 ALAAV 928 LAA+ Sbjct: 1378 RLAAL 1382 Score = 203 bits (517), Expect = 9e-50 Identities = 238/895 (26%), Positives = 346/895 (38%), Gaps = 82/895 (9%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAP-SDVAYXXXXXXXXXXXXAVIRAGGLDE 70 VPV+LSA E +A A + +D D+ P + +A A + AG ++ Sbjct: 1933 VPVLLSARTETALAAQARLLESAVD---DSVPLTALASALATGRAHLPRRAALLAGDHEQ 1989 Query: 71 LTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAEVD 130 L LRA+A+G P T A G V FVFPGQG+QW M + + + Sbjct: 1990 LRGQLRAVAEGVAAPGATTGTASAGG----VVFVFPGQGAQWEGMARGLLSVPVFAESIA 2045 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQI-QGAQFVHGVALARVWRSHGVVPD 189 C S + L PD+ +V + Q F V+LAR+W + GV P Sbjct: 2046 ECDAVLSEVAGFSASEVLEQRPDAP----SLERVDVVQPVLFSVMVSLARLWGACGVSPS 2101 Query: 190 ITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAE 249 +GHS GEI AA VAG ++L + V +V RA L L G + L E+A +IA Sbjct: 2102 AVIGHSQGEIAAAVVAGVLSLEDGVRVVALRAKALRALAGKGGMVSLAAPGERARALIAP 2161 Query: 250 TPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVR--- 306 + + G+ AK + + + +H+ ++ +R Sbjct: 2162 WEDRISVAAVNSPSSVVVSGDPEALAELVARCEDEGVRAKTLPVDYASHSRHVEEIRETI 2221 Query: 307 -ADLDALLPAGRFAETPVQFIGSATADVVTTGTDFAD-YWYTNLRTTVRFDQXXXXXXXX 364 ADLD + + R A P+ S G D YWY NLR+ VRFD+ Sbjct: 2222 LADLDGI--SARRAAIPLY---STLHGERRDGADMGPRYWYDNLRSQVRFDEAVSAAVAD 2276 Query: 365 XXXIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRW 424 FVE+S HP L + E+ V +GS RD E L + + W Sbjct: 2277 GHATFVEMSPHPVLTAAVQEI---AADAVAIGSLHRD-TAEEHLIAELARAHVHGVAVDW 2332 Query: 425 RDQLGDCHAV-LPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHHRIA 483 R+ V LP++PF P R W P+ + + W +A V Sbjct: 2333 RNVFPAAPPVALPNYPFEPQR---YWLAPEVSDQLADSRYRVD-WRPLATTPVDLEGGFL 2388 Query: 484 VVGLDSECAVAGHLRDAAERIEGV-----EVVAPAAADTLLVVAPMISENDPVLAGEELG 538 V G E ++ + A R+ V E +A A + VA ++S + L Sbjct: 2389 VHGSAPE-SLTSAVEKAGGRVVPVASADREALAAALREVPGEVAGVLSVHTGAATHLALH 2447 Query: 539 RRIDEGLLRYPDLLTETTRDVWLVTGR----GEHVPVDRDGSLPVGAAVAAMHRSIAFEH 594 + + E +R P +WLVT R GE PVD P A V + R + E Sbjct: 2448 QSLGEAGVRAP---------LWLVTSRAVALGESEPVD-----PEQAMVWGLGRVMGLET 2493 Query: 595 PDQNFRQLDVPM--GLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDASAA 652 P++ +D+P +A+R G G R++S Sbjct: 2494 PERWGGLVDLPAEPAPGDGEAFVACLGADGHEDQVAIRDHARYGRRLVRAPLGTRESS-- 2551 Query: 653 AAPW-PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL-----P 706 W P G ++TGGTGA+G SR G++ EL Sbjct: 2552 ---WEPAGT---ALVTGGTGALGGHVARHLARCGVEDLVLVSRRGVDAPGAAELEAELVA 2605 Query: 707 LGVEIVAPRCDLTDIPRVRDVAAEFGGQGASL--IVHXXXXXXXXXXXXXXXXXXXXXXX 764 LG + CD+ D ++ + E GQG + +VH Sbjct: 2606 LGAKTTITACDVADREQLSKLLEELRGQGRPVRTVVHTAGVPESRPLHEIGELESVCAAK 2665 Query: 765 XXXXXIENVLAAWPVRPDAR-ILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRR 823 + + L PDA +L SS +G+W N LD +A R R+EGR Sbjct: 2666 VTGARLLDELC-----PDAETFVLFSSGAGVWGSANLGAYSAANAYLDALAHRRRAEGRA 2720 Query: 824 CTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDF-AGDPLVFSAD 877 T+V WG W G G+ D + + R GLR MAP+RA+ Q GD V AD Sbjct: 2721 ATSVAWGAWAGEGMATGD-LEGLTRRGLRPMAPERAIRALHQALDNGDTCVSIAD 2774 >tr|D3U9Y7|D3U9Y7_9ACTO Tax_Id=67297 (sfaG)SubName: Full=Type I polyketide synthase;[Streptomyces flaveolus] Length = 3628 Score = 219 bits (559), Expect = 1e-54 Identities = 281/1005 (27%), Positives = 375/1005 (37%), Gaps = 113/1005 (11%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 VP VLS E + A A+ +L R P DVA AV+ +D+L Sbjct: 473 VPWVLSGRTESALRAQAAALAAHLAERPGDRPGDVALSLATTRPAFEHRAVVVGTDVDDL 532 Query: 72 TAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVE-AYRLDDYRAEVD 130 G+ A+A G+ P V R A G R+AFVFPGQGSQW M E A ++ A +D Sbjct: 533 LRGVAAVAAGEPTPGVVRGTAGHLG---RIAFVFPGQGSQWTGMARELADASTEFAARLD 589 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDI 190 C S D +LA P + + D +Q A + V+LA +W++HGV P Sbjct: 590 ECAAALAPHVDWSLRD-VLADP-AALERVDV----VQPALWAVMVSLAALWQAHGVEPAA 643 Query: 191 TVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAET 250 VGHS GEI AA VAGA++L +A +V ARA L L G + L + A EVIA Sbjct: 644 VVGHSQGEIAAACVAGALSLEDAALLVTARARALRALIGRGGMVSLPLPEAAAREVIAAW 703 Query: 251 PGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADLD 310 L + G+ AK + + + +H+ ++ VRA++ Sbjct: 704 GDRLSVAAVNGPAATVVSGDAAGLDELLAQAERDGLRAKRLPVDYASHSAHVEAVRAEVL 763 Query: 311 ALLPAGRFAETPVQFIGSATADVV-TTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXIF 369 A A T F+ S T + TTG D A YWY NLR VRFD+ F Sbjct: 764 AATAAVTPRATGTAFVSSVTGGFLDTTGLD-AAYWYRNLREPVRFDRAGRALLDAGFTTF 822 Query: 370 VELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQLG 429 +E+SAHP L L ES V+ VGS RRD+ P R ++ A+ WR L Sbjct: 823 IEVSAHPVL---TAALQESDPAVLAVGSLRRDDGGPARFLASLAEAAVRGVPVDWRPALT 879 Query: 430 DCHAV-LPDF--------------PFAPMRAEH---LWA----QPDPLPPVTGLTVAAEQ 467 V LP + P P RA WA D L V G AA + Sbjct: 880 AARTVPLPTYAFQRERLWLEEDAGPITPERAREDSAFWAAVHGSADDLAAVLGADPAARE 939 Query: 468 -----------WHQVAVPEV---SGHHRI---AVVGLDSECAVAGHLRDAAERIEGVEVV 510 WH+ E S +R+ + S A G A + V Sbjct: 940 PIAAVHPLLAAWHERRADESAVDSWRYRVDWTPLTASPSAGAPTGRWLAVAADDPWSDAV 999 Query: 511 APAAADTL-LVVAP-----MISENDPVLAGEELGRRIDE--------GLLRYPDLLTETT 556 A AD + L P ++E AG R D+ LLR D + Sbjct: 1000 VTALADRMDLTRVPAYDPGTVAELTAGTAGVVAVLRPDDPDPLPGLLALLRAHD-RADGG 1058 Query: 557 RDVWLVT-GRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDVPMGLDXXXXXX 615 +W VT G P D P A + R A E P +D+P G Sbjct: 1059 LPLWCVTRGAVATGPADTPAD-PATAQIWGFGRVAALERPQSWGGLIDLPAGATVTGDAL 1117 Query: 616 XXXXXXXXXXDLALRCDV-----AD-------GP-------GTTLWRRGMRDASA--AAA 654 D + DV AD GP + + R +R A A Sbjct: 1118 AGTARADGPPDARIADDVLGARLADRLVAALAGPEDQVAVRASGAFGRRLRRAPADGTTP 1177 Query: 655 PW-PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL-----PLG 708 W PTG +++TGGTG +G R G E EL LG Sbjct: 1178 DWRPTGT---ILVTGGTGGLGGHVARWLARAGAEHLVLTGRRGPEAPGAAELAAELTALG 1234 Query: 709 VEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXX 768 E+ CD D + V AE + H Sbjct: 1235 AEVDIVACDAADRDALARVLAE---HPVDAVFH---LAGIERYRPLDELTPADLTEVAAA 1288 Query: 769 XIENVLAAWPVRPDARI---LLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCT 825 + L + D R+ +L +S +G+W N LD +A R R+EG T Sbjct: 1289 KVTGALLLDELTRDRRLSAFVLFTSGAGVWGSSGQAAYAAANTRLDALAARRRAEGLPAT 1348 Query: 826 AVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFL 885 AV WG W GAG+ D ++ R GL AMAP RAV A D +F Sbjct: 1349 AVAWGHWDGAGMSDGPARAQMLRWGLPAMAPHRAVAALAGALARDEASLVVADIDWPVFA 1408 Query: 886 GTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVLK 930 T R + A +A PAD A R+ AA+L+ Sbjct: 1409 PTFT---LARRSPLLAGLPEATDPADTAPPPAAPAGRLDRAALLE 1450 Score = 78.6 bits (192), Expect = 5e-12 Identities = 59/163 (36%), Positives = 80/163 (49%), Gaps = 8/163 (4%) Query: 77 ALADGDDHPLVTRAAAPQPGSRR--RVAFVFPGQGSQWPSMGVEAYRLDDYRAEVDRCXX 134 A A GD L+ A +P + R R AF+ GQG+Q MG Y A+ Sbjct: 2020 AAAGGDTEALLDALAEARPVTARQGRTAFLCTGQGAQRAGMGAGLYAAHPVYADAFDAVC 2079 Query: 135 XXXXXXXXSPL-DYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDITVG 193 PL D +L+ P + ++Q A F ALA + R GV PD+ G Sbjct: 2080 AEFDRLLDRPLRDLVLSGPADVLDRTAYAQP----ALFAVEAALAALLRHWGVTPDLLAG 2135 Query: 194 HSLGEIGAAYVAGAITLPEAVAIVIARATVLDRL-TGPYRVAV 235 HSLGEI AA++AG ++LP+A A+V AR ++D L G VAV Sbjct: 2136 HSLGEITAAHLAGVLSLPDAAALVAARGRLMDALPAGGAMVAV 2178 Score = 44.3 bits (103), Expect = 0.095 Identities = 61/267 (22%), Positives = 91/267 (34%), Gaps = 19/267 (7%) Query: 654 APWPTGVLDDVVITGGTGAVG-LQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL-PLGVEI 711 AP+ G V++TGGTGA+G L R G E EL G + Sbjct: 3169 APYGDGT---VLVTGGTGALGGLVARHLVTEHGIRDLVLVGRQGAEPPVTAELRAAGARV 3225 Query: 712 VAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIE 771 CD++D + + A+ + +VH Sbjct: 3226 RVAACDVSDRAALAALLADIEPP-LTAVVHAAGVLDDGTLTSLTPERLAAVLRPKADAAW 3284 Query: 772 NVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGL 831 ++ R + +L SS +G + N LD +AE RS G ++ WG Sbjct: 3285 HLHELTEDRDLSAFVLFSSAAGTFGAPGQGNYAAANAALDALAEHRRSRGLPAVSLAWGP 3344 Query: 832 WPG----AGIIDADEITRVERSGLRAMAPDRA---VDTALQDFAGDPLVFSADAQRLALF 884 W G + + + R+ R+G+R +A A +D A + AG D L Sbjct: 3345 WAAESAMTGGLSSGDRARMTRAGVRPLAATEALAVLDAACRTGAGALAALRLDTAALT-- 3402 Query: 885 LGTDADTGTGREATHAAQHRDAGPPAD 911 A TG R AGP D Sbjct: 3403 ----ARTGAPHPLLRDLVRRPAGPARD 3425 >tr|D5UZ35|D5UZ35_TSUPA Tax_Id=521096 SubName: Full=Acyl transferase;[Tsukamurella paurometabola DSM 20162] Length = 1042 Score = 218 bits (555), Expect = 4e-54 Identities = 247/917 (26%), Positives = 344/917 (37%), Gaps = 87/917 (9%) Query: 15 VLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDELTAG 74 VLSA D +A A + RYL VA A++ EL Sbjct: 33 VLSADGADSLAAAAAQLRRYLTEHPQVPLPAVAAALVATRDLRRHRAIVHTDDRGELVTA 92 Query: 75 LRALADGDDHPLVTRAAAPQPG--SRRRVAFVFPGQGSQWPSMGVEAYRLDD-YRAEVDR 131 L ALA P+ T G + AFVFPGQGSQ MG +R YR V++ Sbjct: 93 LDALAADPVRPVGTAVPGLHTGVAAAGAPAFVFPGQGSQRRGMGALFHRESAVYRDTVEK 152 Query: 132 CXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDIT 191 S DYLL + +Q A F+ + LA +WR+ G+ P I Sbjct: 153 IHAIALEVFGSSARDYLLGTGEWEQGGRPVPVEVVQPAIFMQALGLAAMWRAAGIEPRIH 212 Query: 192 VGHSLGEIGAAYVAGAITLPEAVAIVIARA-TVLDRLTGPYRVAVLGITPEQAAEVIAET 250 VGHS GEI AA AG + L + + +V RA V D + +AVLG E+ A ++A T Sbjct: 213 VGHSQGEIAAAVAAGTVGLADGLRLVTRRALAVRDNAPTGHSMAVLGTDRERCAAMLART 272 Query: 251 PGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDG---VRA 307 G+ EL GE FA+EI + +PAHT+ + +R Sbjct: 273 VGFAELSVVNSAHVLCVSGERDVVAGLVAQATERGIFAREIRVEYPAHTSLVGSMWHLRE 332 Query: 308 DLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXX 367 ++ F T IG + V TDF DYW+ NL+ VRFD Sbjct: 333 KWMGVMDHPAFLPTEHLLIGGTLGEAVPADTDFLDYWFWNLKNPVRFDLATRAALDAGAD 392 Query: 368 IFVELSAHPALLFNMGE-LLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRD 426 +EL+ HP L + E + ++ + GS RRD + V V + A Sbjct: 393 RLIELAEHPTLQLALHENIADAGARATVTGSSRRDATDLSEFSSAVADVLVTHARDLDVQ 452 Query: 427 QLGDCHAVLPDFPFAPMRAEHLWA----QPDPLPPVTGLT-VAAEQWHQVAVPEVSGHHR 481 + + P FP AP+ + LWA +P PV T V W + P + Sbjct: 453 RTLVAEELPPGFPAAPLSRQRLWAALPGRPATAGPVRPRTRVLDTVWTDLDAPVSAPPRP 512 Query: 482 IAVVG-LDSECAVAGHLRDAAERIEGVEVVAPAAAD--TLLVVAPMISENDPVLA--GEE 536 +A++ + +A L DAA R + A D +V+ P +E D +A GE Sbjct: 513 LAIIDPTGAHADLAAALLDAAARYGTPARRSDRAGDDEIAVVLVPGSAETDTTIAAVGEL 572 Query: 537 LG-RRIDEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHP 595 L RR G+ + T V V + P DG+ AA+A R+ + P Sbjct: 573 LADRRWWAGVQPAAGIAAVTAGAV--VADPADPGP---DGA---AAAIAVGFRAFGADLP 624 Query: 596 DQNFRQLDVPMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLW--------RRGMR 647 R L DL R D A GT + R +R Sbjct: 625 GVEVRHL-----------------------DLDPRADAAAQAGTAIHALHVAGEPRLALR 661 Query: 648 DASAAAAPW------------PTGVLD---DVVITGGTGAVGLQFXXXXXXXXXXXXXXX 692 + A W P G+L+ +VVI+GGTG +GL F Sbjct: 662 SGAVRAERWVDAEPTETGTEPPAGLLETARNVVISGGTGHLGLAFAAHAAAHGAASVTLL 721 Query: 693 SRNGIEGNRVDEL--------PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASLIVHXXX 744 SR+G G V P V P CD+TD P A G+ L+VH Sbjct: 722 SRSG-GGTTVRHALARIARRHPACAVTVVP-CDVTD-PAAVATALAGAGRAIDLVVHAAV 778 Query: 745 XXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXX 804 + + A PDA +L CSS + Sbjct: 779 GYRRCAATDLDASDFTAAAAAKVGGLRTLAQA---VPDATLLTCSSAAAALPGAGQAWYA 835 Query: 805 XXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTAL 864 N L + A LR GRR AVRWGLW AG +D V +G+ +A A+ Sbjct: 836 ASNTLAEAEAAALRRAGRRAAAVRWGLWEQAGPLDEAGFAAVTAAGVIPLAAPDALAALA 895 Query: 865 QDFAGDPLVFSADAQRL 881 + +P++ + D RL Sbjct: 896 RSTGPEPVITAVDLPRL 912 >sp|Q03133|ERYA3_SACER Tax_Id=1836 (eryA)RecName: Full=Erythronolide synthase, modules 5 and 6; EC=2.3.1.94; AltName: Full=ORF 3; AltName: Full=6-deoxyerythronolide B synthase III; AltName: Full=DEBS 3;[Saccharopolyspora erythraea] Length = 3172 Score = 214 bits (544), Expect = 7e-53 Identities = 268/964 (27%), Positives = 366/964 (37%), Gaps = 92/964 (9%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 VP+VLS E + A + +L + D + AV+ G DE Sbjct: 468 VPLVLSGRDEQAMRAQAGRLADHLAPEPRNSLRDTGFTLATRASAMEHRAVV-VGDRDEA 526 Query: 72 TAGLRALADGDDHPLVTRAAAPQ-PGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAEVD 130 AGLRA+AD + R A Q P S RRVA VFPGQG+QW M + R A+ Sbjct: 527 LAGLRAVAD---RRIADRTATGQGPNSPRRVAMVFPGQGAQWQGMARDLLRESQVFADSI 583 Query: 131 R-CXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPD 189 R C S D L SG D V +Q A F V+LA +WRSHGV P Sbjct: 584 RDCERALAPHVDWSLTDLL-----SGARPLDRVDV-VQPALFAVMVSLAALWRSHGVEPA 637 Query: 190 ITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAE 249 VGHS GEI AA+VAGA+TL +A +V R+ VL RL G +A G+ EQAAE I Sbjct: 638 AVVGHSQGEIAAAHVAGALTLEDAAKLVAVRSRVLRRLGGQGGMASFGLGTEQAAERIGR 697 Query: 250 TPGWLEL-XXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRAD 308 G L + GE A+ I + + +H+ ++ +R + Sbjct: 698 FAGALSIASVNGPRSVVVVAGESGPLDELIAECEAEAHKARRIPVDYASHSPQVESLREE 757 Query: 309 LDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXI 368 L L V + T + T T YWY NLR VRF Sbjct: 758 LLTELAGISPVSADVALYSTTTGQPIDTATMDTAYWYANLREQVRFQDATRQLAEAGFDA 817 Query: 369 FVELSAHPALLFNMGELLEST----RGVVLVGSGRRDEPLPERLADNVITVALADAGYR- 423 FVE+S HP L + L+S G +VG+ RRD LAD AL +A + Sbjct: 818 FVEVSPHPVLTVGIEATLDSALPADAGACVVGTLRRDR---GGLAD--FHTALGEAYAQG 872 Query: 424 ----WRDQLGDCHAV-LPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQ--------WHQ 470 W D V LP +PF + W LP TG E W + Sbjct: 873 VEVDWSPAFADARPVELPVYPF-----QRYW-----LPIPTGGRARDEDDDWRYQVVWRE 922 Query: 471 VAVPEVSGHHRIAVV---GLDSEC--AVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMI 525 S R+ +V G+ SE A+ L + + +V + + T L A Sbjct: 923 AEWESASLAGRVLLVTGPGVPSELSDAIRSGLEQSGATVLTCDVESRSTIGTALEAADTD 982 Query: 526 SENDPVLAGEELGRRIDEGL--LRYPDLL--TETTRDVWLVTGRGEHVPVDRDGSL--PV 579 + + +A G +D L L L +W++T V DG L P Sbjct: 983 ALSTVGVAAVPHGEAVDPSLDALALVQALGAAGVEAPLWVLTRNAVQV---ADGELVDPA 1039 Query: 580 GAAVAAMHRSIAFEHPDQNFRQLD-VPMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPG 638 A V + R + E P + +D V +A+R D G Sbjct: 1040 QAMVGGLGRVVGIEQPGRWGGLVDLVDADAASIRSLAAVLADPRGEEQVAIRAD-----G 1094 Query: 639 TTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIE 698 + R A A P + V++TGGTG +G R G + Sbjct: 1095 IKVARLVPAPARARTHPLEP-LAGTVLVTGGTGGIGAHLARWLARSGAEHLVLLGRRGAD 1153 Query: 699 GNRVDEL-----PLGVEIVAPRCDLTDIPRVRDV-AAEFGGQG--ASLIVHXXXXXXXXX 750 EL LG + CD+ D R+ V AAE +G S ++H Sbjct: 1154 APGASELREELTALGTGVTIAACDVADRARLEAVLAAEAAAEGRTVSAVMHAAGVSTSTP 1213 Query: 751 XXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLL 810 N+ P DA +L SS +G+W N L Sbjct: 1214 LDDLTEAEFTEIADVKVRGTVNLDELCP-DLDAFVLF-SSNAGVWGSPGLASYAAANAFL 1271 Query: 811 DVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDFAGD 870 D A RSEG T++ WGLW G + + + GLRAM PDRAV + Sbjct: 1272 DGFARAARSEGAPVTSIAWGLWAGQNMAGDEGGEYLRSQGLRAMDPDRAV---------E 1322 Query: 871 PLVFSADAQRLALFLGTDADTGTGREATHAAQHRD-----AGPPADAEHHDTGAAVRIAL 925 L + D + ++ + D D E AA+HR AG A+A + G A+ L Sbjct: 1323 ELHITLDHGQTSVSV-VDMDRRRFVELFTAARHRPLFDEIAGARAEARQSEEGPALAQRL 1381 Query: 926 AAVL 929 AA+L Sbjct: 1382 AALL 1385 Score = 206 bits (523), Expect = 2e-50 Identities = 243/909 (26%), Positives = 347/909 (38%), Gaps = 90/909 (9%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAP-SDVAYXXXXXXXXXXXXAVIRAGGLDE 70 VPV+LSA E +A A + +D D+ P + +A A + AG ++ Sbjct: 1938 VPVLLSARTETALAAQARLLESAVD---DSVPLTALASALATGRAHLPRRAALLAGDHEQ 1994 Query: 71 LTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAEVD 130 L LRA+A+G P T A G V FVFPGQG+QW M + + + Sbjct: 1995 LRGQLRAVAEGVAAPGATTGTASAGG----VVFVFPGQGAQWEGMARGLLSVPVFAESIA 2050 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQI-QGAQFVHGVALARVWRSHGVVPD 189 C S + L PD+ +V + Q F V+LAR+W + GV P Sbjct: 2051 ECDAVLSEVAGFSASEVLEQRPDAP----SLERVDVVQPVLFSVMVSLARLWGACGVSPS 2106 Query: 190 ITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAE 249 +GHS GEI AA VAG ++L + V +V RA L L G + L E+A +IA Sbjct: 2107 AVIGHSQGEIAAAVVAGVLSLEDGVRVVALRAKALRALAGKGGMVSLAAPGERARALIAP 2166 Query: 250 TPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVR--- 306 + + G+ AK + + + +H+ ++ +R Sbjct: 2167 WEDRISVAAVNSPSSVVVSGDPEALAELVARCEDEGVRAKTLPVDYASHSRHVEEIRETI 2226 Query: 307 -ADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXX 365 ADLD + A R A + D+ YWY NLR+ VRFD+ Sbjct: 2227 LADLDG-ISARRAAIPLYSTLHGERRDMGPR------YWYDNLRSQVRFDEAVSAQSPDG 2279 Query: 366 XXIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWR 425 FVE+S HP L + E+ V +GS RD E L + + WR Sbjct: 2280 HATFVEMSPHPVLTAAVQEI---AADAVAIGSLHRD-TAEEHLIAELARAHVHGVAVDWR 2335 Query: 426 DQLGDCHAV-LPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHHRIAV 484 + V LP++PF P R W P+ + + W +A V V Sbjct: 2336 NVFPAAPPVALPNYPFEPQR---YWLAPEVSDQLADSRYRVD-WRPLATTPVDLEGGFLV 2391 Query: 485 VGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLV--------VAPMISENDPVLAGEE 536 G E L A E+ GV VA A + L VA ++S + Sbjct: 2392 HGSAPE-----SLTSAVEKAGGVVPVASADREALAAALREVPGEVAGVLSVHTGAANALA 2446 Query: 537 LGRRIDEGLLRYPDLLTETTRDVWLVTGR----GEHVPVDRDGSLPVGAAVAAMHRSIAF 592 L + + E +R P +WLVT R GE PVD P A V + R + Sbjct: 2447 LHQSLGEAGVRAP---------LWLVTSRAVALGESEPVD-----PEQAMVWGLGRVMGL 2492 Query: 593 EHPDQNFRQLDVPM--GLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDAS 650 E P++ +D+P +A+R G G R++S Sbjct: 2493 ETPERWGGLVDLPAEPAPGDGEAFVACLGADGHEDQVAIRDHARYGRRLVRAPLGTRESS 2552 Query: 651 AAAAPW-PTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRNGIEGNRVDEL---- 705 W P G ++TGGTGA+G SR G++ EL Sbjct: 2553 -----WEPAGT---ALVTGGTGALGGHVARHLARCGVEDLVLVSRRGVDAPAAAELEAEL 2604 Query: 706 -PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASL--IVHXXXXXXXXXXXXXXXXXXXXX 762 LG + CD+ D ++ + E GQG + +VH Sbjct: 2605 VALGPKTTITACDVADREQLSKLLEELRGQGRPVRTVVHTAGVPESRPLHEIGELESVCA 2664 Query: 763 XXXXXXXIENVLAAWPVRPDAR-ILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEG 821 + + L PDA +L SS +G+W N LD +A R R+EG Sbjct: 2665 AKVTGARLLDELC-----PDAETFVLFSSGAGVWGSANLGAYSAANAYLDALAHRRRAEG 2719 Query: 822 RRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVDTALQDF-AGDPLVFSADAQR 880 R T+V WG W G G+ D + + R GLR MAPDRA+ Q GD V AD Sbjct: 2720 RAATSVAWGAWAGEGMATGD-LEGLTRRGLRPMAPDRAIRALHQALDNGDTCVSIADVDW 2778 Query: 881 LALFLGTDA 889 A +G A Sbjct: 2779 EAFAVGFTA 2787 >tr|Q0QMN7|Q0QMN7_9ACTO Tax_Id=358765 SubName: Full=Polyketide synthase type I;[Streptomyces sp. Eco86] Length = 4290 Score = 205 bits (521), Expect = 3e-50 Identities = 226/893 (25%), Positives = 344/893 (38%), Gaps = 71/893 (7%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 VPV LS H ED + A + +L DT D+A+ AV+ A ++L Sbjct: 3206 VPVALSGHTEDALRAQAARLAAHLTTHPDTPLRDIAFTAASGRAALDHRAVVLADDPEQL 3265 Query: 72 TAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDD-YRAEVD 130 L ALA+G D P V R A + RRVAFVFPGQGSQW M +E + A + Sbjct: 3266 GERLTALAEGRDVPDVVRGTAAP--NARRVAFVFPGQGSQWAGMALELLDAAPVFAARLT 3323 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDS-GVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPD 189 C S LD L P + G+ D +Q F V+LA +W++HGV PD Sbjct: 3324 ECAAAVEAHADWSVLDVLRQVPGAPGLDRVDV----VQPVTFAVTVSLAALWQAHGVRPD 3379 Query: 190 ITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAE 249 +GHS GEI AA VAGA++L +A A+V R+ L RL+G + + + + E+ Sbjct: 3380 AVIGHSQGEIAAACVAGALSLADAAAVVCLRSRALTRLSGKGGMMSVALPASEVRELF-- 3437 Query: 250 TPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADL 309 T L + G+ A+ I + + +H+ + V+ +L Sbjct: 3438 TDDRLHVAAVNGPASTVVSGDPSALEDLRARCDARGVRARLIAVDYASHSPHVTTVKDEL 3497 Query: 310 DALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXIF 369 D LL PV+ + T + YWYTNLR TVRF F Sbjct: 3498 DGLLAGIAPRAVPVELYSTVTGQRLDPRELTGAYWYTNLRQTVRFADAVGAALDAGIGTF 3557 Query: 370 VELSAHPALLFNMGELLESTRG-VVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQL 428 +E+S HP + + E +++ V++ + RRD+ R ++ + G + Sbjct: 3558 LEVSPHPVVAPGVQETVDAAGARAVVLSTLRRDDGGRPRFTRSLAEAHVRGVGVHLPEVF 3617 Query: 429 GDCHAVLPDFPFAPMRAEHLW--------------------AQPD--PLPPVTGLTVAAE 466 A D P + + W A+P+ P T L + Sbjct: 3618 AGTGARTVDLPTYAFQHQWYWLADQAASRSLGWRYRVEWRPARPNGRTEPDATWLALVPA 3677 Query: 467 QWHQVAVPEVSGHHRIAVVGLDSE----CAVAGHLRDAAERIEGVEVVAPAAADTLLVVA 522 + + ++G + V+ +D+E A+ HLR A +A LL + Sbjct: 3678 GCDEEWLERLTGTLPVRVLPVDAEHADRAALGEHLRRA---------LAEHTPRGLLSLL 3728 Query: 523 PMISENDPVLAGEELGRRIDEGLLRYPDLLTETTRDVWLVT----GRGEHVPVDRDGSLP 578 P G L++ LT T +WLVT G G+ P P Sbjct: 3729 SADRRPHPRHPAVPAGVAATLALVQALGDLT-ATLPLWLVTAGAVGTGDTDPPHD----P 3783 Query: 579 VGAAVAAMHRSIAFEHPDQNFRQLDVPMGLDXXXXXXXXXXXXXXXXD---LALRCDVAD 635 A V + R E+P +D+P D D LA+R A Sbjct: 3784 DAAQVWGLGRVAMLEYPTFWGGLVDLPARPDADALEELRTIMAGGFGDEDQLAVR---AS 3840 Query: 636 GPGTTLWRRGMRDASAAAAPWPTGVLDDVVITGGTGAVGLQFXXXXXXXXXXXXXXXSRN 695 G TL RR +R D V+TGGTGA+G + SR+ Sbjct: 3841 G---TLLRRLVRAPLDGTPAVGWQARDTAVVTGGTGALGPEAARWLAGLGAAHVVLVSRS 3897 Query: 696 GIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVAAEFGGQGASL--IVHXXXXXXX 748 G E V EL GV + A CD+ D V + QG + ++H Sbjct: 3898 GPEAEGVAELTSELDARGVRLTAHACDVADRAAVAALLTGLRDQGEKVRTVLHAAALMRL 3957 Query: 749 XXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNR 808 +++ ++ SS++G+W N Sbjct: 3958 AALPDTDLAEYAAVLDAKVQGARHLVDLLDRDELDALVFYSSIAGVWGSGDHGAYAAANA 4017 Query: 809 LLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERSGLRAMAPDRAVD 861 LD +AE+ R++G T+V WG+W GA + + ++ R GL + P+ A++ Sbjct: 4018 TLDALAEQARADGLPVTSVAWGVWDGARFPEGVDAGQLRRQGLPLIHPESALE 4070 Score = 149 bits (375), Expect = 3e-33 Identities = 129/460 (28%), Positives = 193/460 (41%), Gaps = 17/460 (3%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 VPVVLS H + A + +++ VA AV+ A +L Sbjct: 1507 VPVVLSGHTGAALRAQAERLATHVETHPAATVRQVA-RAAAGRAALTHRAVVTADDPTDL 1565 Query: 72 TAGLRALA-DGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDD-YRAEV 129 LRALA D DD LV A P R FVFPGQG+QW M VE + A + Sbjct: 1566 ARRLRALATDQDDPGLVHGQADVDP----RTVFVFPGQGAQWAGMAVELLDASPVFAARM 1621 Query: 130 DRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPD 189 C S LD + + G ++ + V +Q + V+LA +WRS GV PD Sbjct: 1622 AECAAALGEFTDWSLLD--VVRGEGGAASLERVDV-VQPVSWAVMVSLAALWRSFGVEPD 1678 Query: 190 ITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAE 249 VGHS GEI AA VAGA++L +A + R+ L L G + + + + +A Sbjct: 1679 AVVGHSQGEIAAACVAGALSLRDAAKVSALRSAALRDLAGTGGMMSVALPAAEVERRLAG 1738 Query: 250 TPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADL 309 G + + G+ +A+ + + + +H+ ++ +R L Sbjct: 1739 RDGRVSVAAVNGPAAVVLAGDPAALEGLAAELTADGVWARLVAVDYASHSPQVERIRTTL 1798 Query: 310 DALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXIF 369 L + F + T + + T A+YWY NLR TVRF++ + Sbjct: 1799 LDRLAGLEPRTADIPFYSTVTGEPIDTAALDAEYWYRNLRHTVRFEEAVRALDGAGHRAY 1858 Query: 370 VELSAHPALLFNMGELLESTRG-VVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQL 428 VE+S HP L + + +EST V+VG+ RRD+ P+R ++ + W Sbjct: 1859 VEVSPHPLLTAAVQDTVESTGSTAVVVGTLRRDQGGPDRFLRSLAEAYVRGVPVDWTPAT 1918 Query: 429 GDCHAVLPDFPFAPMRAEHLWAQPDPL----PPVTGLTVA 464 G PD P + +H W P P+ P V GL A Sbjct: 1919 G-TGGPRPDLPAYAFQRQHYWL-PAPVGAADPAVLGLDPA 1956 Score = 105 bits (261), Expect = 5e-20 Identities = 96/364 (26%), Positives = 148/364 (40%), Gaps = 18/364 (4%) Query: 11 RVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDE 70 R P L+A A+ L DA + P D+AY AV+ A + Sbjct: 497 RTPAALTALADRLTTTDAPS------------PLDLAYSLATTRSPLPQRAVLVADTPGD 544 Query: 71 LTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAY-RLDDYRAEV 129 + LRALA G+ H V R A PG R F+F GQG+Q P MG E + R Y A V Sbjct: 545 VPGLLRALAAGEPHARVVRGTAA-PG---RTVFLFAGQGNQRPGMGHEIHLRHPVYAAAV 600 Query: 130 DRCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPD 189 + LD + A S + Q A F VAL R+ S GV PD Sbjct: 601 EEIAEEMRAHLQRPLLDVMSAEEGSRDAALLDEPEYTQPALFAVQVALFRLVESWGVRPD 660 Query: 190 ITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAE 249 +GHS GE+ A +VAGA++LP+A A+V R ++ + ++ + + + Sbjct: 661 AVLGHSFGELAALHVAGAMSLPDACALVATRGRLMQHVPPGGASVLVEASEAELTPDVRA 720 Query: 250 TPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADL 309 + G + + G+ + + + F +H+ +D + + Sbjct: 721 SGGAVSIAALNTPTATVLAGDEEATLEIARKWERSGRRTRRLRIRFASHSAHMDPILDGM 780 Query: 310 DALLPAGRFAETPVQFIGSAT-ADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXI 368 R+ ++ I S T A++ TG D+ ++W + R TVRF Sbjct: 781 RQAASRVRWQRPRLRVISSFTGAELDPTGLDWPEFWARHTRDTVRFADAVRTACAGGART 840 Query: 369 FVEL 372 F+EL Sbjct: 841 FLEL 844 Score = 42.4 bits (98), Expect = 0.36 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 5/103 (4%) Query: 786 LLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGA----GIIDAD 841 +L SSV+G N LD +AER R+ G T++ WGLW + G +D Sbjct: 2519 VLFSSVAGTLGNAGQAAYAAANAALDALAERRRAAGLPATSIAWGLWAESSRMTGHMDDT 2578 Query: 842 EITRVERSGLRAMAPDRAVDTALQDFAGD-PLVFSADAQRLAL 883 + R+ R+G+ + D + A D P V +A R AL Sbjct: 2579 DRARLARAGVLPLDTDTGLTAFDVATARDVPAVLAAPLDREAL 2621 >tr|A1YBQ3|A1YBQ3_SORCE Tax_Id=56 (ambB)SubName: Full=AmbB;[Sorangium cellulosum] Length = 3689 Score = 203 bits (516), Expect = 1e-49 Identities = 246/957 (25%), Positives = 362/957 (37%), Gaps = 64/957 (6%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 +P+++S E + A +L + +DV + A + AG + Sbjct: 482 LPLLVSGRDEAALRAQAGQWAAWLAAHPEAPWADVVHTAAARRTHLEARAAVAAGSAADA 541 Query: 72 TAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDD-YRAEVD 130 A L ALA G H V+ A +R V FV+PGQGSQWP+MG + + A V Sbjct: 542 AAALEALAAGHPHRAVSLGEAR---ARGEVVFVYPGQGSQWPAMGRALLAESEVFAAAVA 598 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDI 190 C S L L V D V +Q A F V L+ VWR+ G+ P Sbjct: 599 ACDAALRPLTGWSVLSVLRGEQGEAVPPADRVDV-VQPALFAMAVGLSAVWRAWGIEPSA 657 Query: 191 TVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAET 250 VGHS GE+ AAYVAGA+TL +A +V R+ ++ R+ G +AV+ + + ++ Sbjct: 658 VVGHSQGEVAAAYVAGALTLEDAARVVALRSQLVRRIAGGGAMAVIERPVGEVEQRLSRF 717 Query: 251 PGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADLD 310 G L + G+ FA+ I++ + +H+ +D + +L+ Sbjct: 718 GGQLSVAAVNTPGSTVVSGDAAAVDRLLAELEAERVFARRIKVDYASHSAHVDAILPELE 777 Query: 311 ALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXIFV 370 A L + + + T +V+ YW NLR VR D+ +FV Sbjct: 778 ATLASVEPRACTIPLYSTVTGEVLAGPELGGGYWCRNLREPVRLDRALSRLLADGHGVFV 837 Query: 371 ELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQLGD 430 E+SAHP L + + RG V+VGS +RD+ RLA + + + W+ L Sbjct: 838 EVSAHPVLAMPL-SAASAERGGVVVGSLQRDDGGLGRLASMLGALHVQGHAVNWQRVLAP 896 Query: 431 CHAVLPDFPFAPMRAEHLW--------------AQPDPLPPVTGLTVAAEQWHQVAVPEV 476 L D P + + W A+ DPL VT + A E+ P Sbjct: 897 YGGALVDLPTYAFQRQRHWLEAPRYAAEDTDGAARRDPLYRVTWIEAALEE-----APWA 951 Query: 477 SGHHRIAVVGLDSECAV---AGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLA 533 + H V+G D A A L E +E +E AAA LV+ ++E P Sbjct: 952 AERH--VVLGADGALASGLGALALAGLPELLEALE--NGAAAPERLVLD--LTEGRPGAV 1005 Query: 534 GEELGRRIDEGL-LRYPDLLTETTRDVWLVTGRGEHVPVDRD-GSLPVG-AAVAAMHRSI 590 E + L L L LV E V D G +G AAV + R++ Sbjct: 1006 AESVHATTRSALALVQAWLAAPRLSGTELVVVTREAVAAGPDEGVAALGPAAVWGLLRTV 1065 Query: 591 AFEHPDQNFRQLDVPMGLDXXXXXXXXXXXXXXXXDLALRCDVADGPGTTLWRRGMRDAS 650 EHP++ R +D+ +LALR A P G + Sbjct: 1066 RVEHPERAVRSVDLGRE-PPDVAVLRRALGTAAEPELALRAGGARAPRLRAVNAGADARA 1124 Query: 651 AAAAPWPTGVLDDVVITGGTGAVGLQF-XXXXXXXXXXXXXXXSRNG---------IEGN 700 AAA P G V ITGGTG +G Q SR G +E Sbjct: 1125 PAAALDPQGT---VWITGGTGELGRQVARHLVAAHGVRHLLLTSRRGAAAPDAEALVEQL 1181 Query: 701 RVDELPLGVEIVAPRCDLTD---IPRVRDVAAEFGGQGASLIVHXXXXXXXXXXXXXXXX 757 R D VE+VA CD+TD + VAA + + +VH Sbjct: 1182 RADGAET-VEVVA--CDVTDGAALSAAVQVAA--AKRPLTAVVHTAGVLADGVLTALTAE 1236 Query: 758 XXXXXXXXXXXXIENVLAAWPVRPDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERL 817 +V AA +P A +L SS+ G N LD A +L Sbjct: 1237 QLTRALAPKVDGACHVYAAAQDQPLAAFVLFSSIVGTLGNAGQANYGAANAFLDAFAAQL 1296 Query: 818 RSEGRRCTAVRWGLWPGAGI-----IDADEITRVERSGLRAMAPDRAVDTALQDFAGDPL 872 R+ G T++ WG W AG+ + A ++ R+ R GL ++ + + + A Sbjct: 1297 RARGVPATSLAWGFWEQAGLGMTAHLGAADLARLGRQGLVPLSVAQGLRLLDRALAHPEA 1356 Query: 873 VFSADAQRLALFLGTDADTGTGREATHAAQHRDAGPPADAEHHDTGAAVRIALAAVL 929 A L+ +D G G P + G A AL A L Sbjct: 1357 TLVPAALDLSALQRAASDAGRVPPLLRGLVRASPGRPTATATPEAGPAAASALRARL 1413 Score = 90.5 bits (223), Expect = 1e-15 Identities = 109/417 (26%), Positives = 158/417 (37%), Gaps = 30/417 (7%) Query: 75 LRALADGDDHPLVTRAA-APQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDD-YRAEVDRC 132 L A A G P T+A+ P S +VA +F GQGSQ MG Y +RA +D Sbjct: 2029 LEAFARGGAAP--TQASQTPVESSTGKVAVLFTGQGSQRAGMGRALYATHPVFRAALDAA 2086 Query: 133 XXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDITV 192 + L A S + Q A F VAL R W + G+ P++ + Sbjct: 2087 CAELDRHLDRPLMSVLFADAGSEAAALLDQTAWAQPALFALEVALYRQWDAWGLRPELLL 2146 Query: 193 GHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPEQAAEVIAETPG 252 GHS+GE+ AA++AG + L +A A+V AR ++ L +A + T ++ ++ + G Sbjct: 2147 GHSIGELAAAHIAGVLDLADASALVAARGRLMQALPLGGAMASVEATEDELRPLLDQHTG 2206 Query: 253 WLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADLDAL 312 L L G+ AK + + H+ ++ + LDA Sbjct: 2207 RLSLAALNTPRQSVVSGDEPAVDQVCAHFTALGRRAKRLVVSHAFHSAHMEPM---LDAF 2263 Query: 313 LPAGR---FAETPVQFIGS-----ATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXX 364 R F + + S A+AD +T+ DYW +R VRF Sbjct: 2264 ARVARGLTFHPPRLPIVSSVTGARASADELTS----PDYWVRQVREPVRFVDGMRALHAA 2319 Query: 365 XXXIFVELSAHPALLFNMGELL--ESTRGVVLVGSGRRDEPLPERLADNVITVALADAGY 422 FVE H L E L + R V S R + L V + Sbjct: 2320 GAATFVECGPHGVLSAAGAECLAPDGARDAGFVPSLRNERDEALALVHAACAVHVRGHAL 2379 Query: 423 RWR---DQLGDCHAVLPDFPFAPMRAEHLWAQ-PDPLPPV--TGLTVAAEQWHQVAV 473 W D G LP + F + + W Q P P P + GLT A W AV Sbjct: 2380 DWLRFFDATGARRVELPTYAF---QRQRYWLQAPRPRPSLEGVGLTAANHPWLGAAV 2433 Score = 40.8 bits (94), Expect = 1.0 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 8/93 (8%) Query: 781 PDARILLCSSVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGI--- 837 P A +L SSV+G N LD +A LR+ G ++ WG W GI Sbjct: 3368 PLAAFMLFSSVAGTLGSSGQANYAAANAFLDGLAAELRTRGVPAMSLAWGFWEQGGIGMT 3427 Query: 838 --IDADEITRVERSGLRAMAPD---RAVDTALQ 865 + A ++ R++R G+ M R +D AL+ Sbjct: 3428 AHLGAADLARLKRQGIAPMTVAHGLRLLDRALE 3460 >tr|D0L275|D0L275_GORB4 Tax_Id=526226 SubName: Full=Acyl transferase;[Gordonia bronchialis] Length = 467 Score = 199 bits (506), Expect = 2e-48 Identities = 157/475 (33%), Positives = 217/475 (45%), Gaps = 34/475 (7%) Query: 7 LCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAG 66 L D V + +S+ +A +ATA+ YL+ D P+ V+ ++RA Sbjct: 6 LPDGTVALPISSEHPAGLADEATAVAGYLETHPDADPAAVSRMLLRTRSLRRHRVIVRAH 65 Query: 67 G----LDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR- 121 G D A LRA A G HP V R P P R VA VFPGQGSQ MG+E +R Sbjct: 66 GDRTRNDATIAALRAAAAGSAHPDVIR---PGPARRLAVAMVFPGQGSQTAGMGIEFHRH 122 Query: 122 LDDYRAEVDRCXXXXXXXXXXSPLDYLLA--HPDSGVSTNDFSQVQIQGAQFVHGVALAR 179 YR V+ SPLDYLL HP+ S +Q A F+H + LAR Sbjct: 123 CASYRRHVEDVNSEFGRVVGISPLDYLLDDDHPEDVRS--------VQPAIFLHTLGLAR 174 Query: 180 VWRSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLT-----GPYRVA 234 +WR G+ P T+GHS GE AA +G ++L + + +V RA ++++ P +A Sbjct: 175 MWRDAGLRPAATIGHSQGEFAAAVESGHLSLRDGIMLVTDRAVGIEKVETSGRHEPSAMA 234 Query: 235 VLGITPEQAAEVIAETPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMW 294 V+G T + + +A GW+EL GE FA+ I + Sbjct: 235 VIGATRDAVEDRLARQTGWVELAVVNSTTIQAISGERTAVDDVVADFTAAGVFARRIRVD 294 Query: 295 FPAHTTALDGVRADLD---ALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTT 351 H++ L + A L A F + + IG + +T A YWY NLR T Sbjct: 295 HAGHSSLLRHYADEFTLSAAHLDATEFHDGEIPCIGGTLGEPITRDLPLAAYWYWNLRNT 354 Query: 352 VRFDQXXXXXXXXXXXIFVELSAHPALLFNMGE-LLESTRGVVLVGSG-RRDEPLPERLA 409 VRFD FVE+S HP +L ++GE + E V+VG+G +R +PL E A Sbjct: 355 VRFDLAIATAVRSGITGFVEMSEHPTMLLSIGETVAEQGADAVIVGTGKKRTDPLAEFTA 414 Query: 410 DNVITVALADAGYRW-RDQLGDCHAVLPDFPFAPMRAEHLWAQP---DPLPPVTG 460 N ++V AD+ + W D L D LPDFP + A WA P P P V G Sbjct: 415 -NALSVFGADSDFHWDADGLVD-QIPLPDFPHSRFDATVYWAPPVAASPSPVVAG 467 >tr|Q331Q3|Q331Q3_9ACTO Tax_Id=201500 (gerSIV)SubName: Full=Putative type I polyketide synthase;[Streptomyces sp. KCTC 0041BP] Length = 1618 Score = 198 bits (504), Expect = 3e-48 Identities = 235/911 (25%), Positives = 345/911 (37%), Gaps = 83/911 (9%) Query: 12 VPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYXXXXXXXXXXXXAVIRAGGLDEL 71 VPVV+S + ++A A+ + R + G DV +V+ A EL Sbjct: 479 VPVVVSGRSAGVVAELASRV-REIAGSGRLV--DVGLSSVVSRSVFEHRSVVLAEDSAEL 535 Query: 72 TAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYRLDDYRAE-VD 130 GL A+A G V G R FVFPGQG+QW M V + AE + Sbjct: 536 NTGLDAVAAGVPSSGVVSGVVSVEGGRS--VFVFPGQGTQWVGMAVRLWAESAVFAESMA 593 Query: 131 RCXXXXXXXXXXSPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVWRSHGVVPDI 190 RC +D+ LA + + +V +Q A F V+LA +WRS GVVPD Sbjct: 594 RCEAAFEGL-----VDWRLADVLGDEAALERVEV-LQPASFAVMVSLAELWRSLGVVPDA 647 Query: 191 TVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDR-LTGPYRVAVLGITPEQAAEVIAE 249 VGHS GEI AA VAG ++L + +V+ RA ++ R L G +A + + E +A Sbjct: 648 VVGHSQGEIAAAVVAGGLSLEDGARVVVLRARLIGRELAGHGGMASVALPVAVVEERLAR 707 Query: 250 TPGWLELXXXXXXXXXXXXGEXXXXXXXXXXXXXXXXFAKEIEMWFPAHTTALDGVRADL 309 G L + G+ A+ + + + +H+ ++ + A+L Sbjct: 708 WAGRLGVAAVNGPSATVVAGDTDAVAEFVTTCEAEGVRARRLPVDYASHSAHVETLAAEL 767 Query: 310 DALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQXXXXXXXXXXXIF 369 + +L R + F + A +V T + A YW+ NLR VRF + +F Sbjct: 768 EEILADVRPVSGEIPFYSTVEAGLVDTASLDAGYWFGNLRRPVRFQETVEQLLADGFPVF 827 Query: 370 VELSAHPALLFNMGELLEST-RGVVLVGSGRRDEPLPERLADNVITVALADAGYRWRDQL 428 VE SAHP L + E ES R V VGS RRDE RL + + W Sbjct: 828 VEASAHPVLTAAVQETAESMGRQVCAVGSLRRDEGGLRRLLTSAAEAFVQGVDVTWPALF 887 Query: 429 GDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAA--------EQWHQVAVPE---VS 477 D A D P P + + W + P VT A+ W +++PE + Sbjct: 888 DDTGARTIDLPTYPFQHQRYWIESSPSTTVTESAAASGIESWRYRVAWKGLSLPESVRLD 947 Query: 478 GHHRIAV-VGLDSECAVAGHLRDAAERIEG-------VEVVAPAAADTLLVVAPMISEND 529 G + V LD++ H + A G V+V A AD ++ +E Sbjct: 948 GRWLLVVPEDLDADGTRVAHDVEHALTTHGATVSRLTVDVTATDRADLSARLSTTAAEEQ 1007 Query: 530 PVLAGEELGRRIDEGLLRYPD------------LLTETTRD------------VWLVTGR 565 L G DE ++PD LL + D +W+VT R Sbjct: 1008 EPLGGILSLLGTDE--RQHPDHPGVDRATAGTMLLAQACADLDADVARGVEPKLWVVT-R 1064 Query: 566 GEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQLDVPMGL----DXXXXXXXXXXXX 621 G + S GA V + R A E P + +D+P Sbjct: 1065 GAVAVSPAERSSSAGAQVWGLGRCAALELPTRWGGMVDLPRAARDTGRQGRQLVRVLSET 1124 Query: 622 XXXXDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGVL------DDVVITGGTGAVGL 675 +ALR A G R + AS+ +A P + V++TGGTG++G Sbjct: 1125 SAEDQVALRASGAYG-------RRLLPASSPSASAPRAAMGGYQPRGTVLVTGGTGSLGG 1177 Query: 676 QFXXXXXXXXXXXXXXXSRNGIEGNRVDEL-----PLGVEIVAPRCDLTDIPRVRDVA-A 729 R G EL LG E+ CD+ D +RD+ A Sbjct: 1178 HLARWLARNGAEHIILAGRRGEGAPGAAELSAEIKELGAEVTVAACDVADRNALRDLLDA 1237 Query: 730 EFGGQGASLIVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXIENVLAAWPVRPDARILLCS 789 GQ S + H ++ + +L + Sbjct: 1238 LPAGQPLSAVFHAAGVPHSAPLAETDVAGLAAVVSGKVVGARHLHDLTREKELDAFVLYA 1297 Query: 790 SVSGLWXXXXXXXXXXXNRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDADEITRVERS 849 S +G+W N LD +AE+ R+EG T+V WGLW G G+ + Sbjct: 1298 SGAGVWGSGGQSAYGAANAALDALAEQRRAEGLTATSVSWGLWDGGGMAGEQGEEFLTAL 1357 Query: 850 GLRAMAPDRAV 860 GLRAM P+ AV Sbjct: 1358 GLRAMEPESAV 1368 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.320 0.137 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 7,186,685,005 Number of extensions: 281673461 Number of successful extensions: 646787 Number of sequences better than 10.0: 5663 Number of HSP's gapped: 637688 Number of HSP's successfully gapped: 7992 Length of query: 997 Length of database: 4,236,830,644 Length adjustment: 148 Effective length of query: 849 Effective length of database: 2,385,666,772 Effective search space: 2025431089428 Effective search space used: 2025431089428 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 86 (37.7 bits)