BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_4712
         (370 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|A0R1D4|A0R1D4_MYCS2 Tax_Id=246196 SubName: Full=Pyruvate dehy...   702   0.0  
tr|A1TCG3|A1TCG3_MYCVP Tax_Id=350058 SubName: Full=Pyruvate dehy...   570   e-160
tr|Q1B5V1|Q1B5V1_MYCSS Tax_Id=164756 SubName: Full=Pyruvate dehy...   565   e-159
tr|A3Q2N1|A3Q2N1_MYCSJ Tax_Id=164757 SubName: Full=Pyruvate dehy...   565   e-159
tr|A1UJ85|A1UJ85_MYCSK Tax_Id=189918 SubName: Full=Pyruvate dehy...   565   e-159
tr|Q73XK0|Q73XK0_MYCPA Tax_Id=1770 (pdhA)SubName: Full=PdhA;[Myc...   516   e-144
tr|D5PH18|D5PH18_9MYCO Tax_Id=525368 (pdhA)SubName: Full=Pyruvat...   515   e-144
tr|A0QDB9|A0QDB9_MYCA1 Tax_Id=243243 SubName: Full=Pyruvate dehy...   514   e-144
tr|Q7TYG0|Q7TYG0_MYCBO Tax_Id=1765 (pdhA)SubName: Full=PROBABLE ...   508   e-142
tr|O06161|O06161_MYCTU Tax_Id=1773 (pdhA)SubName: Full=2-oxoisov...   508   e-142
tr|C6DMY4|C6DMY4_MYCTK Tax_Id=478434 SubName: Full=Pyruvate dehy...   508   e-142
tr|C1AEW3|C1AEW3_MYCBT Tax_Id=561275 (pdhA)SubName: Full=Putativ...   508   e-142
tr|A5WQA7|A5WQA7_MYCTF Tax_Id=336982 SubName: Full=Pyruvate dehy...   508   e-142
tr|A5U5J4|A5U5J4_MYCTA Tax_Id=419947 (pdhA)SubName: Full=Putativ...   508   e-142
tr|A1KLJ2|A1KLJ2_MYCBP Tax_Id=410289 (pdhA)SubName: Full=Probabl...   508   e-142
tr|D6G4G3|D6G4G3_MYCTU Tax_Id=478435 SubName: Full=Pyruvate dehy...   508   e-142
tr|D6FYN8|D6FYN8_MYCTU Tax_Id=611304 SubName: Full=Pyruvate dehy...   508   e-142
tr|D5Y587|D5Y587_MYCTU Tax_Id=520141 SubName: Full=Pyruvate dehy...   508   e-142
tr|A4KP21|A4KP21_MYCTU Tax_Id=395095 SubName: Full=Pyruvate dehy...   508   e-142
tr|D5ZJ09|D5ZJ09_MYCTU Tax_Id=537210 SubName: Full=Pyruvate dehy...   508   e-142
tr|D5YHX7|D5YHX7_MYCTU Tax_Id=520140 SubName: Full=Pyruvate dehy...   508   e-142
tr|B2HNK2|B2HNK2_MYCMM Tax_Id=216594 (pdhA)SubName: Full=Pyruvat...   508   e-142
tr|D6FJ60|D6FJ60_MYCTU Tax_Id=611303 SubName: Full=Pyruvate dehy...   507   e-141
tr|D5YUB3|D5YUB3_MYCTU Tax_Id=515616 SubName: Full=Pyruvate dehy...   506   e-141
tr|A0PU62|A0PU62_MYCUA Tax_Id=362242 (pdhA)SubName: Full=Pyruvat...   499   e-139
tr|D5Z622|D5Z622_MYCTU Tax_Id=537209 SubName: Full=Pyruvate dehy...   438   e-121
tr|D5XWD2|D5XWD2_MYCTU Tax_Id=515617 SubName: Full=Pyruvate dehy...   387   e-105
tr|D6F6V1|D6F6V1_MYCTU Tax_Id=611302 SubName: Full=Pyruvate dehy...   347   1e-93
tr|D3CG12|D3CG12_9ACTO Tax_Id=648999 SubName: Full=Pyruvate dehy...   323   2e-86
tr|C7QIE8|C7QIE8_CATAD Tax_Id=479433 SubName: Full=Pyruvate dehy...   318   6e-85
tr|D1S2D5|D1S2D5_9ACTO Tax_Id=644283 SubName: Full=Pyruvate dehy...   318   6e-85
tr|A4X6P8|A4X6P8_SALTO Tax_Id=369723 SubName: Full=Pyruvate dehy...   315   8e-84
tr|A8M1D7|A8M1D7_SALAI Tax_Id=391037 SubName: Full=Pyruvate dehy...   311   1e-82
tr|C9Z4T3|C9Z4T3_STRSW Tax_Id=680198 (pdhA)SubName: Full=PROBABL...   310   3e-82
tr|C4RDT0|C4RDT0_9ACTO Tax_Id=219305 SubName: Full=Pyruvate dehy...   309   3e-82
tr|C1YR72|C1YR72_NOCDA Tax_Id=446468 SubName: Full=Pyruvate dehy...   306   2e-81
tr|D5WUI8|D5WUI8_9BACL Tax_Id=562970 SubName: Full=Pyruvate dehy...   306   3e-81
tr|A0LQU9|A0LQU9_ACIC1 Tax_Id=351607 SubName: Full=Pyruvate dehy...   305   5e-81
tr|Q0SGE7|Q0SGE7_RHOSR Tax_Id=101510 (pdhA1)SubName: Full=Pyruva...   305   6e-81
tr|C5CCR2|C5CCR2_MICLC Tax_Id=465515 SubName: Full=Pyruvate/2-ox...   305   6e-81
tr|C1AW95|C1AW95_RHOOB Tax_Id=632772 (bkdF)SubName: Full=Branche...   305   6e-81
tr|D3LQ13|D3LQ13_MICLU Tax_Id=596312 SubName: Full=Dehydrogenase...   305   6e-81
tr|D6BAU5|D6BAU5_9ACTO Tax_Id=457425 SubName: Full=Branched-chai...   305   8e-81
tr|A0JUQ5|A0JUQ5_ARTS2 Tax_Id=290399 SubName: Full=Pyruvate dehy...   304   1e-80
tr|B8HEC4|B8HEC4_ARTCA Tax_Id=452863 SubName: Full=Pyruvate dehy...   303   3e-80

>tr|A0R1D4|A0R1D4_MYCS2 Tax_Id=246196 SubName: Full=Pyruvate
           dehydrogenase E1 component, alpha subunit;
           EC=1.2.4.1;[Mycobacterium smegmatis]
          Length = 370

 Score =  702 bits (1812), Expect = 0.0
 Identities = 351/370 (94%), Positives = 351/370 (94%)

Query: 1   MAMQYSSAPGYDTGFDPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNL 60
           MAMQYSSAPGYDTGFDPEPVQLVAA                   ETLSWLYESMVVTRNL
Sbjct: 1   MAMQYSSAPGYDTGFDPEPVQLVAADGSPSPDRPPSRYSRDLPPETLSWLYESMVVTRNL 60

Query: 61  DVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMG 120
           DVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMG
Sbjct: 61  DVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMG 120

Query: 121 AVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEG 180
           AVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEG
Sbjct: 121 AVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEG 180

Query: 181 DAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVL 240
           DAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVL
Sbjct: 181 DAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVL 240

Query: 241 ACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYR 300
           ACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYR
Sbjct: 241 ACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYR 300

Query: 301 TYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRD 360
           TYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRD
Sbjct: 301 TYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRD 360

Query: 361 QLLSELAKEA 370
           QLLSELAKEA
Sbjct: 361 QLLSELAKEA 370


>tr|A1TCG3|A1TCG3_MYCVP Tax_Id=350058 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring);
           EC=1.2.4.1;[Mycobacterium vanbaalenii]
          Length = 361

 Score =  570 bits (1469), Expect = e-160
 Identities = 279/353 (79%), Positives = 304/353 (86%), Gaps = 3/353 (0%)

Query: 18  EPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELALFA 77
           EP+QLVA                    ETL+WLYESMVVTR LD EFVNLQRQGELALFA
Sbjct: 12  EPIQLVAPDGAPTPESRYRRDLPP---ETLAWLYESMVVTRELDTEFVNLQRQGELALFA 68

Query: 78  SCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKC 137
           SCRGQEAAQIGAAACLRKTDWLFPQYRE+GAFL+R I PAQ+GA+WRG+WHGGL FT +C
Sbjct: 69  SCRGQEAAQIGAAACLRKTDWLFPQYRELGAFLVRAIAPAQLGALWRGRWHGGLGFTDRC 128

Query: 138 VAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAPCV 197
           VAP++IPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEA NLA VF APCV
Sbjct: 129 VAPVSIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEALNLAAVFGAPCV 188

Query: 198 FFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARRGE 257
           FF+QNNQWAISVPV RQ AGPT+AHRAIGYGMPG+RVDGNDVLAC+AVM +AA RAR G 
Sbjct: 189 FFVQNNQWAISVPVERQHAGPTLAHRAIGYGMPGVRVDGNDVLACFAVMEQAAARAREGG 248

Query: 258 GPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEERV 317
           GPT IEAVTYRMGPHTTSDDPTRYR  EEVE W ARDPIARYRTYL++ GVWT+RLEERV
Sbjct: 249 GPTFIEAVTYRMGPHTTSDDPTRYRSDEEVEHWRARDPIARYRTYLEHTGVWTQRLEERV 308

Query: 318 AARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAKEA 370
           A RS RL AELRDA++  PD+D  E+FDTVY DITP+LARQRD+LL+ELAKEA
Sbjct: 309 AHRSQRLRAELRDAVITEPDIDIGEVFDTVYHDITPDLARQRDELLAELAKEA 361


>tr|Q1B5V1|Q1B5V1_MYCSS Tax_Id=164756 SubName: Full=Pyruvate
           dehydrogenase (Lipoamide); EC=1.2.4.1;[Mycobacterium
           sp.]
          Length = 356

 Score =  565 bits (1456), Expect = e-159
 Identities = 280/357 (78%), Positives = 303/357 (84%), Gaps = 3/357 (0%)

Query: 14  GFDPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGEL 73
           G + +PVQLV A                   ETL+WLYE+MVVTR+LD EFV+LQRQGEL
Sbjct: 3   GVELDPVQLVGADGSPSAQQRYSRDLPP---ETLAWLYETMVVTRDLDTEFVHLQRQGEL 59

Query: 74  ALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSF 133
           AL+ASCRGQEAAQIGA ACLRKTDWLFPQYREIGAFLLRGI PAQM AVWRGKWHGGL F
Sbjct: 60  ALYASCRGQEAAQIGATACLRKTDWLFPQYREIGAFLLRGIAPAQMAAVWRGKWHGGLEF 119

Query: 134 TGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFR 193
           T KC API+IPIGT GLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGD HEA NLA V++
Sbjct: 120 TAKCCAPISIPIGTQGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDVHEAMNLAAVYQ 179

Query: 194 APCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERA 253
            PCVFF+QNNQWAISVPV RQ AGP+IAHRA GYGMPG+RVDGNDVLAC+AVMSEAA RA
Sbjct: 180 VPCVFFVQNNQWAISVPVQRQVAGPSIAHRAAGYGMPGVRVDGNDVLACFAVMSEAAARA 239

Query: 254 RRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERL 313
           R G GPTLIEAVTYR+GPHTTSDDPTRYR   EV+ W ARDPI RYRTYLQ  GVW+ERL
Sbjct: 240 RAGGGPTLIEAVTYRLGPHTTSDDPTRYRDQSEVDRWRARDPIPRYRTYLQGAGVWSERL 299

Query: 314 EERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAKEA 370
           EERVAARS RL AELRDA+VGAPD D +E+FDTVY DITP+LA QRD+LL+ELAKEA
Sbjct: 300 EERVAARSKRLRAELRDAVVGAPDFDVSEVFDTVYHDITPDLAEQRDRLLAELAKEA 356


>tr|A3Q2N1|A3Q2N1_MYCSJ Tax_Id=164757 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring);
           EC=1.2.4.1;[Mycobacterium sp.]
          Length = 356

 Score =  565 bits (1456), Expect = e-159
 Identities = 280/357 (78%), Positives = 303/357 (84%), Gaps = 3/357 (0%)

Query: 14  GFDPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGEL 73
           G + +PVQLV A                   ETL+WLYE+MVVTR+LD EFV+LQRQGEL
Sbjct: 3   GVELDPVQLVGADGSPSAQQRYSRDLPP---ETLAWLYETMVVTRDLDTEFVHLQRQGEL 59

Query: 74  ALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSF 133
           AL+ASCRGQEAAQIGA ACLRKTDWLFPQYREIGAFLLRGI PAQM AVWRGKWHGGL F
Sbjct: 60  ALYASCRGQEAAQIGATACLRKTDWLFPQYREIGAFLLRGIAPAQMAAVWRGKWHGGLEF 119

Query: 134 TGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFR 193
           T KC API+IPIGT GLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGD HEA NLA V++
Sbjct: 120 TAKCCAPISIPIGTQGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDVHEAMNLAAVYQ 179

Query: 194 APCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERA 253
            PCVFF+QNNQWAISVPV RQ AGP+IAHRA GYGMPG+RVDGNDVLAC+AVMSEAA RA
Sbjct: 180 VPCVFFVQNNQWAISVPVQRQVAGPSIAHRAAGYGMPGVRVDGNDVLACFAVMSEAAARA 239

Query: 254 RRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERL 313
           R G GPTLIEAVTYR+GPHTTSDDPTRYR   EV+ W ARDPI RYRTYLQ  GVW+ERL
Sbjct: 240 RAGGGPTLIEAVTYRLGPHTTSDDPTRYRDQSEVDRWRARDPIPRYRTYLQGAGVWSERL 299

Query: 314 EERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAKEA 370
           EERVAARS RL AELRDA+VGAPD D +E+FDTVY DITP+LA QRD+LL+ELAKEA
Sbjct: 300 EERVAARSKRLRAELRDAVVGAPDFDVSEVFDTVYHDITPDLAEQRDRLLAELAKEA 356


>tr|A1UJ85|A1UJ85_MYCSK Tax_Id=189918 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring);
           EC=1.2.4.1;[Mycobacterium sp.]
          Length = 356

 Score =  565 bits (1456), Expect = e-159
 Identities = 280/357 (78%), Positives = 303/357 (84%), Gaps = 3/357 (0%)

Query: 14  GFDPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGEL 73
           G + +PVQLV A                   ETL+WLYE+MVVTR+LD EFV+LQRQGEL
Sbjct: 3   GVELDPVQLVGADGSPSAQQRYSRDLPP---ETLAWLYETMVVTRDLDTEFVHLQRQGEL 59

Query: 74  ALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSF 133
           AL+ASCRGQEAAQIGA ACLRKTDWLFPQYREIGAFLLRGI PAQM AVWRGKWHGGL F
Sbjct: 60  ALYASCRGQEAAQIGATACLRKTDWLFPQYREIGAFLLRGIAPAQMAAVWRGKWHGGLEF 119

Query: 134 TGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFR 193
           T KC API+IPIGT GLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGD HEA NLA V++
Sbjct: 120 TAKCCAPISIPIGTQGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDVHEAMNLAAVYQ 179

Query: 194 APCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERA 253
            PCVFF+QNNQWAISVPV RQ AGP+IAHRA GYGMPG+RVDGNDVLAC+AVMSEAA RA
Sbjct: 180 VPCVFFVQNNQWAISVPVQRQVAGPSIAHRAAGYGMPGVRVDGNDVLACFAVMSEAAARA 239

Query: 254 RRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERL 313
           R G GPTLIEAVTYR+GPHTTSDDPTRYR   EV+ W ARDPI RYRTYLQ  GVW+ERL
Sbjct: 240 RAGGGPTLIEAVTYRLGPHTTSDDPTRYRDQSEVDRWRARDPIPRYRTYLQGAGVWSERL 299

Query: 314 EERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAKEA 370
           EERVAARS RL AELRDA+VGAPD D +E+FDTVY DITP+LA QRD+LL+ELAKEA
Sbjct: 300 EERVAARSKRLRAELRDAVVGAPDFDVSEVFDTVYHDITPDLAEQRDRLLAELAKEA 356


>tr|Q73XK0|Q73XK0_MYCPA Tax_Id=1770 (pdhA)SubName:
           Full=PdhA;[Mycobacterium paratuberculosis]
          Length = 363

 Score =  516 bits (1328), Expect = e-144
 Identities = 252/353 (71%), Positives = 286/353 (81%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D +PVQLVAA                   ETLSWLYE MV+TR LD EFVNL+RQG+LAL
Sbjct: 12  DLQPVQLVAADGTPTPEHRYSRELPA---ETLSWLYEMMVLTRELDGEFVNLKRQGQLAL 68

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           FASCRGQEAAQ+GA ACLRKTDWLFPQYRE+GAFL+RGI P  +GAVWRG WHGGL FT 
Sbjct: 69  FASCRGQEAAQVGATACLRKTDWLFPQYRELGAFLVRGIPPGNVGAVWRGTWHGGLGFTD 128

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP++IPIGT  LHAVGAAMAAQRLGEDSVT+AFLGDGATS GD HEA N A VFR P
Sbjct: 129 KCCAPLSIPIGTQSLHAVGAAMAAQRLGEDSVTIAFLGDGATSVGDVHEALNFAAVFRTP 188

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVFF+QNNQWAIS+PV++Q A P++AH+AIGYGMPGIRVDGNDVLACYAV +EAA RAR 
Sbjct: 189 CVFFVQNNQWAISLPVAKQTAAPSLAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARA 248

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G GPTLIEA+TYR+GPHTTSDDPTRYR  +EV+ WAA DPI RYR+YLQ  G+W+ERLEE
Sbjct: 249 GRGPTLIEAITYRLGPHTTSDDPTRYRTQDEVDHWAALDPIPRYRSYLQGQGLWSERLEE 308

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           RV  R++R+ AELRDA+  APD+D  E+F  VYA+ITPEL  QR  L +EL K
Sbjct: 309 RVIGRATRMRAELRDAVFDAPDLDVDEVFTAVYAEITPELQAQRRALRTELEK 361


>tr|D5PH18|D5PH18_9MYCO Tax_Id=525368 (pdhA)SubName: Full=Pyruvate
           dehydrogenase complex E1 component;
           EC=1.2.4.1;[Mycobacterium parascrofulaceum ATCC BAA-614]
          Length = 366

 Score =  515 bits (1327), Expect = e-144
 Identities = 254/353 (71%), Positives = 283/353 (80%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLVAA                   ETL WLYE MVVTR LD EFVNL+RQGEL L
Sbjct: 12  DLEPVQLVAADGTPTPEHRYGRDLRA---ETLCWLYEMMVVTRELDTEFVNLKRQGELGL 68

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           FASCRGQEAAQ+GA ACLRKTDWLFPQYRE+GA+L+RGI P  +GAVWRG WHGGL FT 
Sbjct: 69  FASCRGQEAAQVGAVACLRKTDWLFPQYRELGAYLVRGIPPGHVGAVWRGTWHGGLEFTK 128

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP +IPIGT  LHAVGAAMAAQRLGEDSVTVAFLGDGATS GD HEA N A VF  P
Sbjct: 129 KCCAPTSIPIGTQALHAVGAAMAAQRLGEDSVTVAFLGDGATSVGDVHEALNFAAVFATP 188

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVFF+QNNQWAISVP+ +Q   P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 189 CVFFVQNNQWAISVPIHKQTKAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 248

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTTSDDP+RYR  EEV+ WAA DPI RYRTYLQ  G+W++RLE+
Sbjct: 249 GDGPTLIEAVTYRLGPHTTSDDPSRYRTQEEVDRWAALDPIPRYRTYLQAQGLWSDRLED 308

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           RVAAR+ R+ AELRDA+ GAPD D  E+F TVYA++TP L  Q  QL +EL +
Sbjct: 309 RVAARAKRMRAELRDAVFGAPDFDIEEVFTTVYAEMTPGLRAQLQQLRAELER 361


>tr|A0QDB9|A0QDB9_MYCA1 Tax_Id=243243 SubName: Full=Pyruvate
           dehydrogenase E1 component, alpha subunit;
           EC=1.2.4.1;[Mycobacterium avium]
          Length = 363

 Score =  514 bits (1324), Expect = e-144
 Identities = 252/353 (71%), Positives = 286/353 (81%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D +PVQLVAA                   ETLSWLYE MV+TR LD EFVNL+RQG+LAL
Sbjct: 12  DLQPVQLVAADGTPTSEHRYSRELPA---ETLSWLYEMMVLTRELDGEFVNLKRQGQLAL 68

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           FASCRGQEAAQ+GA ACLRKTDWLFPQYRE+GAFL+RGI P  +GAVWRG WHGGL FT 
Sbjct: 69  FASCRGQEAAQVGATACLRKTDWLFPQYRELGAFLVRGIPPGNVGAVWRGTWHGGLGFTD 128

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP++IPIGT  LHAVGAAMAAQRLGEDSVT+AFLGDGATS GD HEA N A VFR P
Sbjct: 129 KCCAPLSIPIGTQTLHAVGAAMAAQRLGEDSVTIAFLGDGATSVGDVHEALNFAAVFRTP 188

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVFF+QNNQWAIS+PV++Q A P++AH+AIGYGMPGIRVDGNDVLACYAV +EAA RAR 
Sbjct: 189 CVFFVQNNQWAISLPVAKQTASPSLAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARA 248

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G GPTLIEA+TYR+GPHTTSDDPTRYR  +EV+ WAA DPI RYR+YLQ  G+W+ERLEE
Sbjct: 249 GGGPTLIEAITYRLGPHTTSDDPTRYRTQDEVDHWAALDPIPRYRSYLQGQGLWSERLEE 308

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           RV  R++R+ AELRDA+  APD+D  E+F  VYA+ITPEL  QR  L +EL K
Sbjct: 309 RVIGRATRMRAELRDAVFDAPDLDVDEVFTAVYAEITPELQAQRRALRTELEK 361


>tr|Q7TYG0|Q7TYG0_MYCBO Tax_Id=1765 (pdhA)SubName: Full=PROBABLE
           PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA
           (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE)
           (PYRUVIC DEHYDROGENASE); EC=1.2.4.1;[Mycobacterium
           bovis]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|O06161|O06161_MYCTU Tax_Id=1773 (pdhA)SubName:
           Full=2-oxoisovalerate dehydrogenase E1 component, alpha
           subunit, putative; EC=1.2.4.4; SubName: Full=PROBABLE
           PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA
           (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE)
           (PYRUVIC DEHYDROGENASE); EC=1.2.4.1;[Mycobacterium
           tuberculosis]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|C6DMY4|C6DMY4_MYCTK Tax_Id=478434 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|C1AEW3|C1AEW3_MYCBT Tax_Id=561275 (pdhA)SubName: Full=Putative
           pyruvate dehydrogenase E1 component subunit alpha;
           EC=1.2.4.1;[Mycobacterium bovis]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|A5WQA7|A5WQA7_MYCTF Tax_Id=336982 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|A5U5J4|A5U5J4_MYCTA Tax_Id=419947 (pdhA)SubName: Full=Putative
           2-oxoisovalerate dehydrogenase E1 component subunit
           alpha;[Mycobacterium tuberculosis]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|A1KLJ2|A1KLJ2_MYCBP Tax_Id=410289 (pdhA)SubName: Full=Probable
           pyruvate dehydrogenase E1 component (Alpha subunit)
           pdhA; EC=1.2.4.1;[Mycobacterium bovis]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|D6G4G3|D6G4G3_MYCTU Tax_Id=478435 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis KZN 605]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|D6FYN8|D6FYN8_MYCTU Tax_Id=611304 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis K85]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|D5Y587|D5Y587_MYCTU Tax_Id=520141 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis T85]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|A4KP21|A4KP21_MYCTU Tax_Id=395095 SubName: Full=Pyruvate
           dehydrogenase E1 component (Alpha subunit)
           pdhA;[Mycobacterium tuberculosis str. Haarlem]
          Length = 367

 Score =  508 bits (1309), Expect = e-142
 Identities = 248/353 (70%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|D5ZJ09|D5ZJ09_MYCTU Tax_Id=537210 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis T17]
          Length = 349

 Score =  508 bits (1308), Expect = e-142
 Identities = 241/324 (74%), Positives = 274/324 (84%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           ETL WLYE MVVTR LD EFVNLQRQGELAL+  CRGQEAAQ+GAAACLRKTDWLFPQYR
Sbjct: 24  ETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYR 83

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           E+G +L+RGI P  +G  WRG WHGGL FT KC AP+++PIGT  LHAVGAAMAAQRL E
Sbjct: 84  ELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDE 143

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           DSVTVAFLGDGATSEGD HEA N A VF  PCVF++QNNQWAIS+PVSRQ A P+IAH+A
Sbjct: 144 DSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKA 203

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           IGYGMPGIRVDGNDVLACYAVM+EAA RAR G+GPTLIEAVTYR+GPHTT+DDPTRYR  
Sbjct: 204 IGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQ 263

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
           EEV+ WA  DPI RYRTYLQ+ G+W++RLEE+V AR+  + +ELRDA+  APD D  E+F
Sbjct: 264 EEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVF 323

Query: 345 DTVYADITPELARQRDQLLSELAK 368
            TVYA+ITP L  QR+QL +ELA+
Sbjct: 324 TTVYAEITPGLQAQREQLRAELAR 347


>tr|D5YHX7|D5YHX7_MYCTU Tax_Id=520140 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit pdhA; Flags:
           Fragment;[Mycobacterium tuberculosis EAS054]
          Length = 345

 Score =  508 bits (1308), Expect = e-142
 Identities = 241/324 (74%), Positives = 274/324 (84%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           ETL WLYE MVVTR LD EFVNLQRQGELAL+  CRGQEAAQ+GAAACLRKTDWLFPQYR
Sbjct: 20  ETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYR 79

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           E+G +L+RGI P  +G  WRG WHGGL FT KC AP+++PIGT  LHAVGAAMAAQRL E
Sbjct: 80  ELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDE 139

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           DSVTVAFLGDGATSEGD HEA N A VF  PCVF++QNNQWAIS+PVSRQ A P+IAH+A
Sbjct: 140 DSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKA 199

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           IGYGMPGIRVDGNDVLACYAVM+EAA RAR G+GPTLIEAVTYR+GPHTT+DDPTRYR  
Sbjct: 200 IGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQ 259

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
           EEV+ WA  DPI RYRTYLQ+ G+W++RLEE+V AR+  + +ELRDA+  APD D  E+F
Sbjct: 260 EEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVF 319

Query: 345 DTVYADITPELARQRDQLLSELAK 368
            TVYA+ITP L  QR+QL +ELA+
Sbjct: 320 TTVYAEITPGLQAQREQLRAELAR 343


>tr|B2HNK2|B2HNK2_MYCMM Tax_Id=216594 (pdhA)SubName: Full=Pyruvate
           dehydrogenase E1 component (Alpha subunit)
           PdhA;[Mycobacterium marinum]
          Length = 363

 Score =  508 bits (1307), Expect = e-142
 Identities = 251/349 (71%), Positives = 282/349 (80%), Gaps = 3/349 (0%)

Query: 18  EPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELALFA 77
           EPVQLV A                   ETL WLYE MVVTR LD EF+NL+RQGELALFA
Sbjct: 14  EPVQLVNADGEPTDEHRYSRDLPE---ETLCWLYEMMVVTRELDAEFINLKRQGELALFA 70

Query: 78  SCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKC 137
           SCRGQEAAQ+GA ACLRKTDWLFPQYRE+GA+L+RGI P  +GA WRG WHGGL FT KC
Sbjct: 71  SCRGQEAAQVGATACLRKTDWLFPQYRELGAYLVRGIPPGHVGAAWRGTWHGGLEFTKKC 130

Query: 138 VAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAPCV 197
            API++PIGT  LHAVGAAMAAQRLGEDSVTVAFLGDGATSEGD HEA N A VF A CV
Sbjct: 131 CAPISVPIGTQALHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDVHEALNFAAVFDAGCV 190

Query: 198 FFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARRGE 257
           F++QNNQWAISVPVS+Q A P+IAH+AIGYGMPGIRVDGNDVLACYAV +EAA RARRG+
Sbjct: 191 FYVQNNQWAISVPVSKQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARRGD 250

Query: 258 GPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEERV 317
           GPTLIEAVTYR+G HTT+DDP RYR  EEV+ W A DPI+RYR+YLQ  G+W++RLEERV
Sbjct: 251 GPTLIEAVTYRVGAHTTADDPGRYRSQEEVDHWLALDPISRYRSYLQGQGLWSQRLEERV 310

Query: 318 AARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSEL 366
           AARS RL AELR+A+ GA D D  ++F TV+A+ITP L  QR QL +EL
Sbjct: 311 AARSGRLRAELREAVFGASDFDVDDVFTTVFAEITPGLQTQRQQLRAEL 359


>tr|D6FJ60|D6FJ60_MYCTU Tax_Id=611303 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis CPHL_A]
          Length = 367

 Score =  507 bits (1305), Expect = e-141
 Identities = 247/353 (69%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL ++LA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAKLAR 365


>tr|D5YUB3|D5YUB3_MYCTU Tax_Id=515616 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis 02_1987]
          Length = 367

 Score =  506 bits (1304), Expect = e-141
 Identities = 247/353 (69%), Positives = 281/353 (79%), Gaps = 3/353 (0%)

Query: 16  DPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELAL 75
           D EPVQLV                     ETL WLYE MVVTR LD EFVNLQRQGELAL
Sbjct: 16  DLEPVQLVGPDGTPTAERRYHRDLPE---ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72

Query: 76  FASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTG 135
           +  CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT 
Sbjct: 73  YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132

Query: 136 KCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAP 195
           KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA + A VF  P
Sbjct: 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALDFAAVFTTP 192

Query: 196 CVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARR 255
           CVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR 
Sbjct: 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252

Query: 256 GEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEE 315
           G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE
Sbjct: 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312

Query: 316 RVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365


>tr|A0PU62|A0PU62_MYCUA Tax_Id=362242 (pdhA)SubName: Full=Pyruvate
           dehydrogenase E1 component (Alpha subunit)
           PdhA;[Mycobacterium ulcerans]
          Length = 355

 Score =  499 bits (1284), Expect = e-139
 Identities = 247/349 (70%), Positives = 278/349 (79%), Gaps = 3/349 (0%)

Query: 18  EPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELALFA 77
           EPVQLV A                   ETL WLYE MVVTR LD EF+NL+RQGELALFA
Sbjct: 6   EPVQLVNADGEPTDEHRYSRDLPE---ETLCWLYEMMVVTRELDAEFINLKRQGELALFA 62

Query: 78  SCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKC 137
           SCRGQEAAQ+GA ACLRKTDWLFPQYRE+GA+L+RGI P  +GA WRG WHGGL FT KC
Sbjct: 63  SCRGQEAAQVGATACLRKTDWLFPQYRELGAYLVRGIPPGHVGAAWRGTWHGGLEFTKKC 122

Query: 138 VAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAPCV 197
             PI++PIGT  LHAVGAA AAQRLGEDSVTVAFLGDGATSEGD HEA N A VF A CV
Sbjct: 123 CVPISVPIGTQALHAVGAAQAAQRLGEDSVTVAFLGDGATSEGDVHEALNFAAVFDAGCV 182

Query: 198 FFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARRGE 257
           F++QNNQWAISVPVS+Q A P+IAH+AIGYGMPGIRVDGNDVLACYAV + AA RARRG+
Sbjct: 183 FYVQNNQWAISVPVSKQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVTAVAAARARRGD 242

Query: 258 GPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEERV 317
           GPTLIEAVTYR+G HTT+DDP RYR  EEV+ W A DPI+RYR+YLQ  G+W++RLE RV
Sbjct: 243 GPTLIEAVTYRVGAHTTADDPGRYRSQEEVDHWLALDPISRYRSYLQGQGLWSQRLEVRV 302

Query: 318 AARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSEL 366
           AARS RL AELR+A+ GA D D  ++F TV+A+ITP L  QR QL +EL
Sbjct: 303 AARSGRLRAELREAVFGASDFDVDDVFTTVFAEITPGLQTQRQQLRAEL 351


>tr|D5Z622|D5Z622_MYCTU Tax_Id=537209 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis GM 1503]
          Length = 284

 Score =  438 bits (1126), Expect = e-121
 Identities = 206/282 (73%), Positives = 238/282 (84%)

Query: 87  IGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIG 146
           +GAAACLRKTDWLFPQYRE+G +L+RGI P  +G  WRG WHGGL FT KC AP+++PIG
Sbjct: 1   MGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIG 60

Query: 147 THGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWA 206
           T  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  PCVF++QNNQWA
Sbjct: 61  TQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWA 120

Query: 207 ISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVT 266
           IS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR G+GPTLIEAVT
Sbjct: 121 ISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVT 180

Query: 267 YRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCA 326
           YR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE+V AR+  + +
Sbjct: 181 YRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRS 240

Query: 327 ELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 241 ELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 282


>tr|D5XWD2|D5XWD2_MYCTU Tax_Id=515617 SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit
           pdhA;[Mycobacterium tuberculosis T92]
          Length = 259

 Score =  387 bits (993), Expect = e-105
 Identities = 183/253 (72%), Positives = 211/253 (83%)

Query: 116 PAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDG 175
           P  +G  WRG WHGGL FT KC AP+++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDG
Sbjct: 5   PGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDG 64

Query: 176 ATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVD 235
           ATSEGD HEA N A VF  PCVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVD
Sbjct: 65  ATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVD 124

Query: 236 GNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDP 295
           GNDVLACYAVM+EAA RAR G+GPTLIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DP
Sbjct: 125 GNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDP 184

Query: 296 IARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPEL 355
           I RYRTYLQ+ G+W++RLEE+V AR+  + +ELRDA+  APD D  E+F TVYA+ITP L
Sbjct: 185 IPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGL 244

Query: 356 ARQRDQLLSELAK 368
             QR+QL +ELA+
Sbjct: 245 QAQREQLRAELAR 257


>tr|D6F6V1|D6F6V1_MYCTU Tax_Id=611302 SubName: Full=Pyruvate
           dehydrogenase E1 component pdhA;[Mycobacterium
           tuberculosis T46]
          Length = 230

 Score =  347 bits (890), Expect = 1e-93
 Identities = 167/228 (73%), Positives = 194/228 (85%)

Query: 141 IAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFI 200
           +++PIGT  LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A VF  PCVF++
Sbjct: 1   MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 60

Query: 201 QNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPT 260
           QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EAA RAR G+GPT
Sbjct: 61  QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 120

Query: 261 LIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEERVAAR 320
           LIEAVTYR+GPHTT+DDPTRYR  EEV+ WA  DPI RYRTYLQ+ G+W++RLEE+V AR
Sbjct: 121 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 180

Query: 321 SSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368
           +  + +ELRDA+  APD D  E+F TVYA+ITP L  QR+QL +ELA+
Sbjct: 181 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 228


>tr|D3CG12|D3CG12_9ACTO Tax_Id=648999 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring) E1 component, alpha
           subunit; EC=1.2.4.1;[Micromonospora sp. L5]
          Length = 388

 Score =  323 bits (828), Expect = 2e-86
 Identities = 171/366 (46%), Positives = 221/366 (60%), Gaps = 5/366 (1%)

Query: 7   SAPGYDTGFDP--EPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEF 64
           +AP    GF P  EPV+L+                     ETL  +Y  MVV R  DV+ 
Sbjct: 22  AAPDPSAGFMPQREPVRLLEPDGTPLPARDDYPEPPV---ETLREMYRRMVVGRRFDVQA 78

Query: 65  VNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWR 124
             L +QG LA++ S RGQEA QIG    LR TDW+FP YRE  A   RG+ P ++  + R
Sbjct: 79  TALTKQGRLAVYPSARGQEACQIGGVLALRDTDWVFPTYRESMALTARGLDPVEVLTLLR 138

Query: 125 GKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHE 184
           G WH G        AP   P+ T  +HA G A      G D+V +AF+GDGATSEGD HE
Sbjct: 139 GDWHCGYDPAATHTAPQCTPLATQCVHAAGLAYGESYQGRDTVALAFIGDGATSEGDFHE 198

Query: 185 AFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYA 244
             N A VF+AP V+ +QNN++AISVP+SRQ A P++A++ +GYG+P  +VDGND +A  A
Sbjct: 199 GINFAAVFKAPVVYLVQNNKYAISVPLSRQTAAPSLAYKGVGYGVPSEQVDGNDPVAVLA 258

Query: 245 VMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQ 304
           V+  A   AR G+GP L+EA TYRM PHT +DD TRYR A+EVEAW  RDPIAR   YL+
Sbjct: 259 VLERAVAHARAGKGPYLVEAHTYRMEPHTNADDQTRYRDADEVEAWRDRDPIARLEAYLR 318

Query: 305 NIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLS 364
           + GV  +     +AA +    A LR  +   P VDP  +FD VYA+ TP+LA QR+ + +
Sbjct: 319 SRGVLDDAAVAAIAAEAEEYAAALRRRMDAQPTVDPLSLFDHVYAEPTPQLAEQREMVRA 378

Query: 365 ELAKEA 370
           ELA +A
Sbjct: 379 ELAADA 384


>tr|C7QIE8|C7QIE8_CATAD Tax_Id=479433 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring) E1 component, alpha
           subunit; EC=1.2.4.1;[Catenulispora acidiphila]
          Length = 383

 Score =  318 bits (816), Expect = 6e-85
 Identities = 166/361 (45%), Positives = 218/361 (60%), Gaps = 2/361 (0%)

Query: 10  GYDTGFDPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQR 69
           G+DT  DP P+Q +                        +W   +MV+ R  DV+   + R
Sbjct: 17  GFDTILDPSPLQYLDEHGALSGALRDDVPELDPKELLATW--RAMVIGRRFDVQATTMVR 74

Query: 70  QGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHG 129
           QG LA++ S  GQEA +IGA   LR TDW FP YR+  + + RGI P Q   + RG WH 
Sbjct: 75  QGRLAVYPSSFGQEACEIGAILALRPTDWFFPTYRDCVSMVTRGIDPVQTLTLLRGDWHC 134

Query: 130 GLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLA 189
           G        AP   P+ T   HA G A+AA+  G+D+V +AF GDG TSEGD HEA N A
Sbjct: 135 GYDSQVWRTAPQCTPLATQAPHAAGLALAAKLAGDDTVALAFCGDGGTSEGDFHEALNFA 194

Query: 190 TVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEA 249
            V++AP +FF+QNNQ+AISVP+++Q     +AH+A+GYGM G+RVDGNDV+A   V++EA
Sbjct: 195 AVYQAPAIFFVQNNQYAISVPLAKQTHAAALAHKAVGYGMAGVRVDGNDVIAVRRVVAEA 254

Query: 250 AERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVW 309
           AERARRG+GPTLIEAVTYRM  HT +DD TRYR   EVE W  RDP+AR  TYL+  G+ 
Sbjct: 255 AERARRGQGPTLIEAVTYRMQAHTNADDATRYRDESEVEYWKVRDPLARLETYLRAAGLL 314

Query: 310 TERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAKE 369
            E +       +  L  ++R  +   P+VD  ++F  VYA+ TP+L  Q   L +EL  E
Sbjct: 315 GEDVVAEANQAAEDLANDMRSRLGEEPEVDHRDLFRHVYAEPTPQLLEQAAALQAELDAE 374

Query: 370 A 370
           A
Sbjct: 375 A 375


>tr|D1S2D5|D1S2D5_9ACTO Tax_Id=644283 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring) E1 component, alpha
           subunit; EC=1.2.4.1;[Micromonospora aurantiaca ATCC
           27029]
          Length = 388

 Score =  318 bits (816), Expect = 6e-85
 Identities = 160/326 (49%), Positives = 206/326 (63%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           ETL  +Y  MVV R  DV+   L +QG LA++ S RGQEA QIG    LR TDW+FP YR
Sbjct: 59  ETLREMYRRMVVGRRFDVQATALTKQGRLAVYPSARGQEACQIGGVLALRDTDWVFPTYR 118

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           E  A   RG+ P ++  + RG WH G        AP   P+ T  +HA G A      G 
Sbjct: 119 ESMALTARGLDPVEVLTLLRGDWHCGYDPAATHTAPQCTPLATQCVHAAGLAYGESYQGR 178

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           D+V +AF+GDGATSEGD HE  N A VF+AP V+ +QNN++AISVP+SRQ A P++A++ 
Sbjct: 179 DTVALAFIGDGATSEGDFHEGINFAAVFKAPVVYLVQNNKYAISVPLSRQTAAPSLAYKG 238

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           +GYG+P  +VDGND +A  AV+  A   AR G+GP L+EA TYRM PHT +DD TRYR A
Sbjct: 239 VGYGVPSEQVDGNDPVAVLAVLERAVAHARAGKGPYLVEAHTYRMEPHTNADDQTRYRDA 298

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
           +EVEAW  RDPIAR   YL+  G   +     +AA +    A LR  +   P  DP  +F
Sbjct: 299 DEVEAWRDRDPIARLEAYLRARGALDDAAVAAIAAEAEEYAAALRRRMDSQPTADPLSLF 358

Query: 345 DTVYADITPELARQRDQLLSELAKEA 370
           D VYA+ TP+LA QR+ + +ELA +A
Sbjct: 359 DHVYAEPTPQLAEQREMVRAELAADA 384


>tr|A4X6P8|A4X6P8_SALTO Tax_Id=369723 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring);
           EC=1.2.4.1;[Salinispora tropica]
          Length = 382

 Score =  315 bits (806), Expect = 8e-84
 Identities = 156/325 (48%), Positives = 209/325 (64%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           E L  LY  MV+ R  D++   L +QG LA++ S RGQEA Q+GA   LR  DW+FP YR
Sbjct: 53  EVLVELYRRMVLGRRFDLQATALTKQGRLAVYPSARGQEACQVGAILALRDDDWVFPTYR 112

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           E  A   RGI P ++  + RG WH G     +  AP   P+ T  +HA G A      G 
Sbjct: 113 ESMALTARGIDPVEVLTLLRGDWHCGYDPAVRRTAPQCTPLATQCVHAAGLAYGEAYQGR 172

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           D+V +AF+GDGATSEGD HE  N A VF+AP V+F+QNNQ+AISVP+SRQ A P++A++ 
Sbjct: 173 DTVALAFIGDGATSEGDFHEGVNFAAVFKAPVVYFVQNNQYAISVPLSRQTAAPSLAYKG 232

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           +GYG+P  +VDGND +A  AV++ A   AR G GP L+EA TYRM PHT +DD  RYR A
Sbjct: 233 VGYGVPSEQVDGNDPVAVLAVLNRAVAHARAGHGPFLVEAHTYRMEPHTNADDAARYRDA 292

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
           +EV +W  RDP+ R  T+L++ G   +    RVAA++    A+LR+ +   P VDP  +F
Sbjct: 293 DEVASWQDRDPVVRLETHLRDRGALDDSTVARVAAQAEEYAADLRERMHDKPTVDPLTLF 352

Query: 345 DTVYADITPELARQRDQLLSELAKE 369
           D VYA+ TP+L  QR+Q+ +EL  +
Sbjct: 353 DHVYAEPTPQLVEQREQVRAELTAD 377


>tr|A8M1D7|A8M1D7_SALAI Tax_Id=391037 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring);
           EC=1.2.4.1;[Salinispora arenicola]
          Length = 382

 Score =  311 bits (796), Expect = 1e-82
 Identities = 155/325 (47%), Positives = 207/325 (63%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           E L  LY  MV+ R  D +   L +QG LA++ S RGQEA Q+GA   LR  DW+FP YR
Sbjct: 53  EALVELYRRMVIGRRFDQQATALTKQGRLAVYPSARGQEACQVGAVLALRDDDWVFPTYR 112

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           E  A   RGI P ++  + RG WH G     +  AP   P+ T  +HA G A      G 
Sbjct: 113 ESMALTARGIDPVEVLTLLRGDWHCGYDPVLRRSAPQCTPLATQCVHAAGLAYGEAYQGR 172

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           ++V + F+GDGATSEGD HE  N A VF+AP V+F+QNN++AISVP+SRQ A P++A++ 
Sbjct: 173 ETVALTFIGDGATSEGDFHEGVNFAAVFKAPVVYFVQNNRYAISVPLSRQTAAPSLAYKG 232

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           +GYG+P  +VDGND +A  AV++ A   AR G GP L+EA TYRM PHT +DD TRYR A
Sbjct: 233 VGYGVPSEQVDGNDPVAVLAVLTRAVAHARAGHGPFLVEAHTYRMEPHTNADDATRYRDA 292

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
           +EV  W  RDP+AR  TYL+      + +  RVA ++    A+LR+ +   P VDP  +F
Sbjct: 293 DEVAVWQDRDPVARLETYLRARRALDDTIVARVAGQAEEYAADLRERMHDKPTVDPMTLF 352

Query: 345 DTVYADITPELARQRDQLLSELAKE 369
           D VYA+ TP+LA QR+Q+ +EL  +
Sbjct: 353 DHVYAEPTPQLAEQREQVRAELTAD 377


>tr|C9Z4T3|C9Z4T3_STRSW Tax_Id=680198 (pdhA)SubName: Full=PROBABLE
           PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA
           (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE)
           (PYRUVIC DEHYDROGENASE);[Streptomyces scabies]
          Length = 384

 Score =  310 bits (793), Expect = 3e-82
 Identities = 160/326 (49%), Positives = 207/326 (63%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           E L   +  MV+ R  D +   L +QG LA++ S RGQEA Q+GAA  LR  DWLFP YR
Sbjct: 43  EILREAHRRMVLGRRFDTQATALTKQGRLAVYPSSRGQEACQVGAALALRPDDWLFPTYR 102

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           +  A + RGI P ++  + RG+WH G        AP   P+ T  LHA G A + +R GE
Sbjct: 103 DSVALVTRGIDPVEVLTLLRGEWHCGYDPAATRTAPQCTPLATQVLHATGMAESLRRKGE 162

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           D V +A +GDGATSEGD HEA N A VFRAP VF +QNN++AISVP++RQ A P +A++ 
Sbjct: 163 DGVAMALVGDGATSEGDFHEALNFAAVFRAPVVFLVQNNKYAISVPLARQTAAPALAYKG 222

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           +G+GM   +VDGND +A  AV++EA   AR G GP L+EA TYRM  HT +DD TRYR A
Sbjct: 223 VGHGMRSEQVDGNDPVAVLAVLTEAVAHARAGHGPFLVEAHTYRMDAHTNADDATRYRDA 282

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
           +EVE W A DP+ R  TYL+  G  T++    V   +  L AELR  +      DP E+F
Sbjct: 283 DEVERWRAADPLIRLETYLRARGALTDQDIAAVGEEAEELAAELRAGMNAETVGDPLELF 342

Query: 345 DTVYADITPELARQRDQLLSELAKEA 370
           D VYA++TP+L  QR  L +ELA+ A
Sbjct: 343 DHVYAELTPQLREQRALLAAELAETA 368


>tr|C4RDT0|C4RDT0_9ACTO Tax_Id=219305 SubName: Full=Pyruvate
           dehydrogenase;[Micromonospora sp. ATCC 39149]
          Length = 397

 Score =  309 bits (792), Expect = 3e-82
 Identities = 155/323 (47%), Positives = 204/323 (63%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           E L  +Y  MVV R  D +   L +QG LA++ S RGQEA Q+GA   +   DW+FP YR
Sbjct: 68  EALREMYRRMVVGRRFDAQATALTKQGRLAVYPSSRGQEACQVGAVLAVGHNDWVFPTYR 127

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           E  A + RGI P ++  + RG WH G        AP   P+ T  +HA G A      G 
Sbjct: 128 ESMALVSRGIDPVEVLTLLRGDWHCGYDPARVRTAPQCTPLATQCVHAAGLAYGEAHQGR 187

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           D+V +AF+GDGATSEGD HE  N A VF+AP VFF+QNN++AISVP+SRQ A P++A++ 
Sbjct: 188 DTVALAFIGDGATSEGDFHEGVNFAAVFKAPVVFFVQNNKYAISVPLSRQTAAPSLAYKG 247

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           +GYG+P  +VDGND +A  AV++ A   AR G GP L+EA TYRM PHT +DD TRYR  
Sbjct: 248 VGYGVPSEQVDGNDPVAVLAVLTRAVAHARAGNGPYLVEAHTYRMEPHTNADDATRYRDG 307

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
            EV+ W  RDPIAR  TYL+  G   +     +AA++    A+LR+ +   P+VDP  +F
Sbjct: 308 AEVDTWRDRDPIARLETYLRTRGALDDAAVAAIAAQAEGYAADLRERMHVQPEVDPLSLF 367

Query: 345 DTVYADITPELARQRDQLLSELA 367
           D VYA  TP+L  QR+ + +ELA
Sbjct: 368 DHVYATPTPQLVEQRELVRAELA 390


>tr|C1YR72|C1YR72_NOCDA Tax_Id=446468 SubName: Full=Pyruvate
           dehydrogenase E1 component, alpha subunit;[Nocardiopsis
           dassonvillei subsp. dassonvillei DSM 43111]
          Length = 361

 Score =  306 bits (785), Expect = 2e-81
 Identities = 159/325 (48%), Positives = 206/325 (63%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           E L   Y S+V+ R ++ +   L RQG LA++ S  GQEA Q GAA  L + DWLFP YR
Sbjct: 35  ERLLAAYTSLVIGRRVNDQASALVRQGRLAVYPSSHGQEACQTGAALALAEGDWLFPTYR 94

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           +  A + RG+ P Q+  + +G WH G       VAP A P+ T  LHAVG A AA+  GE
Sbjct: 95  DTAAVVARGVDPVQVLTLLKGDWHSGYDPYAHRVAPQATPLATQLLHAVGVAHAARLRGE 154

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           D+V +A  GDGATSEGD HEA N A VFRAP VFF+QNN++AISVP++RQ A P++AH+ 
Sbjct: 155 DTVVMAMCGDGATSEGDFHEALNFAAVFRAPVVFFVQNNEYAISVPLARQTAAPSLAHKG 214

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           +GYG+   RVDGND  A  AV+  A   AR GEGP L+EA TYRM  HT +DD TRYR  
Sbjct: 215 VGYGVNAERVDGNDTPAVLAVLDRAVAAARAGEGPQLVEAHTYRMQAHTNADDATRYRTQ 274

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
           EEV+ W ARDP+ R   YL    V T+  + R+A  +  + A +R+ +    D +PAE+F
Sbjct: 275 EEVDPWEARDPLLRMEAYLTRKRVLTKARKARIAEDAEAVAAAMREGVTRDTDPEPAELF 334

Query: 345 DTVYADITPELARQRDQLLSELAKE 369
             V+A  TP+L  Q   L  EL++E
Sbjct: 335 AHVFATPTPQLDEQAAFLADELSRE 359


>tr|D5WUI8|D5WUI8_9BACL Tax_Id=562970 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring) E1 component, alpha
           subunit; EC=1.2.4.1;[Bacillus tusciae DSM 2912]
          Length = 361

 Score =  306 bits (784), Expect = 3e-81
 Identities = 159/318 (50%), Positives = 198/318 (62%), Gaps = 1/318 (0%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           + L  +Y  MV+ R  D   +NLQRQG +  +A   GQEAAQIG+ A L K DW+FP YR
Sbjct: 32  DRLVGMYRGMVLARTFDERALNLQRQGRIGTYAPFSGQEAAQIGSFAALEKDDWVFPSYR 91

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           E+   +  G+   +      G   G        + P+ I I +  LHAVGA  A +  GE
Sbjct: 92  ELAGMIYHGLPMERALLYSMGHPDGAKMPEDSRMFPVQIVIASQLLHAVGAGWACRLKGE 151

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
            SV  A+ GDGATSEGD HEA NLA+VF  P VFF QNN WAISVPVS Q    T+A RA
Sbjct: 152 RSVAAAYFGDGATSEGDFHEALNLASVFSVPVVFFCQNNGWAISVPVSHQMRSATVAQRA 211

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           + YG+ GIRVDGNDVLA Y  M  A +RAR GEGPTL+EAVTYR+GPHTT+DDPTRYR  
Sbjct: 212 VAYGIEGIRVDGNDVLAVYEGMLRAVDRARAGEGPTLVEAVTYRLGPHTTADDPTRYRDE 271

Query: 285 EEVEAW-AARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEM 343
           EE++ W   RDPI R+R +L+N G+W+E  E     ++ R   E        P  DP+  
Sbjct: 272 EELKRWRERRDPIVRFRKFLENRGIWSEEQERAEWEQARRAVDEAVVRAESYPKADPSFA 331

Query: 344 FDTVYADITPELARQRDQ 361
           F+ VYA +TP+L  QRD+
Sbjct: 332 FEHVYASMTPDLCNQRDE 349


>tr|A0LQU9|A0LQU9_ACIC1 Tax_Id=351607 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring);
           EC=1.2.4.1;[Acidothermus cellulolyticus]
          Length = 372

 Score =  305 bits (782), Expect = 5e-81
 Identities = 168/301 (55%), Positives = 188/301 (62%), Gaps = 2/301 (0%)

Query: 50  LYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAF 109
           LY  MV  R  DVE   LQRQGEL ++A   GQEAAQIG+A  LR TD +FP YRE G  
Sbjct: 50  LYRDMVALRRFDVEATTLQRQGELGIWAQVLGQEAAQIGSARALRPTDMVFPTYREHGVA 109

Query: 110 LLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRL-GEDSVT 168
             RGI P  +  ++RG   GG       VAP  I IG H LHAVG AMA QR  G DS+ 
Sbjct: 110 WCRGIPPEDILQLFRGINFGGWDPAAYHVAPYTIVIGAHALHAVGYAMALQREPGNDSIA 169

Query: 169 VAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYG 228
           +A+ GDGATSEGD +EAF  A  +RAP +FF+QNNQWAISVP  RQ   P +  RA G+G
Sbjct: 170 IAYFGDGATSEGDVNEAFVFAASYRAPVIFFVQNNQWAISVPEIRQSPIP-LYQRAAGFG 228

Query: 229 MPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVE 288
            PG+RVDGNDVLAC AV   AA   R G GP LIEA TYRMG HTTSDDPTRYR A EVE
Sbjct: 229 FPGVRVDGNDVLACLAVTRAAAAHVRAGNGPYLIEAFTYRMGAHTTSDDPTRYRLAAEVE 288

Query: 289 AWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVY 348
           AW  RDPI R + YL   G         V   + RL   +R A V  PD  P  MFD VY
Sbjct: 289 AWKLRDPIERVKAYLSRSGAADADFFTDVDTEAERLAERVRAACVTMPDPGPLTMFDHVY 348

Query: 349 A 349
           A
Sbjct: 349 A 349


>tr|Q0SGE7|Q0SGE7_RHOSR Tax_Id=101510 (pdhA1)SubName: Full=Pyruvate
           dehydrogenase E1 component alpha subunit;
           EC=1.2.4.1;[Rhodococcus sp.]
          Length = 365

 Score =  305 bits (781), Expect = 6e-81
 Identities = 169/349 (48%), Positives = 205/349 (58%), Gaps = 1/349 (0%)

Query: 19  PVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELALFAS 78
           PVQL+                     + L  LYE +VV R +DVE V LQRQGEL L+A 
Sbjct: 8   PVQLIQPDGRRVFRPDYTSLVRDIGPDQLRGLYEDLVVARRMDVEAVALQRQGELGLWAP 67

Query: 79  CRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCV 138
             GQEAAQ+G+A  LR  D+ F  YRE      RG+ P  M  +WRG  H     +   V
Sbjct: 68  MLGQEAAQVGSARALRSDDYAFISYREHAVAYCRGVDPGVMTRMWRGCAHSAWDPSSVNV 127

Query: 139 APIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVF 198
              AI +G+ GLHA G AM A   G +  T+A+ GDGATS+GD  EA   +  F AP VF
Sbjct: 128 TNPAIVVGSQGLHATGYAMGAHLDGAEIATIAYFGDGATSQGDLAEALGFSMSFNAPVVF 187

Query: 199 FIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARRGEG 258
           F QNNQ+AIS PV  Q   P IA RA GYGMP +RVDGNDVLA  AV  +A +RAR G G
Sbjct: 188 FCQNNQFAISEPVHLQSPVP-IAQRAAGYGMPALRVDGNDVLAVLAVTRQATQRAREGSG 246

Query: 259 PTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEERVA 318
           PT IEAVTYRMGPHTTSDDPTRYR A E E W ARDPI R R  L   G+  +     V 
Sbjct: 247 PTFIEAVTYRMGPHTTSDDPTRYRAAAETEVWKARDPINRMRRLLDREGLLDDTFLAGVQ 306

Query: 319 ARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELA 367
           A +  + A LR   +GAPD +P ++F+ VY+   P +  +R+Q  + LA
Sbjct: 307 AAADDVAARLRSGTIGAPDPEPLDLFEHVYSADHPLIDEEREQYAAYLA 355


>tr|C5CCR2|C5CCR2_MICLC Tax_Id=465515 SubName:
           Full=Pyruvate/2-oxoglutarate dehydrogenase complex,
           dehydrogenase component alpha subunit;[Micrococcus
           luteus]
          Length = 400

 Score =  305 bits (781), Expect = 6e-81
 Identities = 150/324 (46%), Positives = 213/324 (65%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           E L   Y  +V+ R ++ +   L RQG +A++ S  GQEA+++ AA CL + DWLFP YR
Sbjct: 71  EELLAAYRHLVIGRRVNDQAYALVRQGRMAVYPSSHGQEASEVAAAVCLGEDDWLFPTYR 130

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           +  A + RG+ P ++   ++G WH G       V+  + P+ T  LHAVG A AA+  GE
Sbjct: 131 DTVAVIARGVPPLEVMVAYQGTWHQGYDPQKHRVSIQSTPLTTQMLHAVGMAKAARLRGE 190

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           + V +A +GDG TSEGD HEA N A VF+ P +FF+QNN++AISVP ++Q A P++AH+A
Sbjct: 191 EVVCLAMVGDGGTSEGDFHEALNFAAVFKLPVIFFVQNNKFAISVPFAKQSAAPSLAHKA 250

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           +GYG+ G RVDGND+ A  AV+  A E  R+G+GP L+EA TYRM  HT +DDP+RYR  
Sbjct: 251 VGYGLAGERVDGNDLGALLAVLGRAVELCRQGQGPFLVEADTYRMQAHTNTDDPSRYRDD 310

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
            EV+ W ARDP+ R   YL++ G  TE +  ++A  +  +  +LRDA+    ++DP E+F
Sbjct: 311 AEVKEWEARDPLRRMTAYLESTGALTEEVSAQIARDAEDVAQQLRDAMNAETELDPLELF 370

Query: 345 DTVYADITPELARQRDQLLSELAK 368
           D VY+  TP+LA QR QL  EL++
Sbjct: 371 DHVYSVQTPQLAAQRAQLAEELSR 394


>tr|C1AW95|C1AW95_RHOOB Tax_Id=632772 (bkdF)SubName:
           Full=Branched-chain alpha-keto acid dehydrogenase E1
           alpha subunit; EC=1.2.4.4;[Rhodococcus opacus]
          Length = 365

 Score =  305 bits (781), Expect = 6e-81
 Identities = 171/349 (48%), Positives = 204/349 (58%), Gaps = 1/349 (0%)

Query: 19  PVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGELALFAS 78
           PVQL+                     + L  LYE +VV R +DVE V LQRQGEL L+A 
Sbjct: 8   PVQLIQPDGLRVFRPDYTSLVRDIRPDQLRDLYEDLVVARRMDVEAVALQRQGELGLWAP 67

Query: 79  CRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCV 138
             GQEAAQ+G+A  LR  D+ F  YRE      RG+ P  M  +WRG  H     +   V
Sbjct: 68  LLGQEAAQVGSARALRPDDYAFISYREHAVAYCRGVDPGVMTRMWRGCAHSAWDPSSVNV 127

Query: 139 APIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVF 198
              AI +G+ GLHA G AM A   G +  T+A+ GDGATS+GD  EA   +  F AP VF
Sbjct: 128 TNPAIVVGSQGLHATGYAMGAHLDGAEIATIAYFGDGATSQGDLAEALGFSMSFNAPVVF 187

Query: 199 FIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAERARRGEG 258
           F QNNQ+AIS PV  Q   P IA RA GYGMP +RVDGNDVLA  AV  +A +RAR G G
Sbjct: 188 FCQNNQFAISEPVHLQSPVP-IAQRAAGYGMPALRVDGNDVLAVLAVTRQATQRAREGSG 246

Query: 259 PTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTERLEERVA 318
           PT IEA+TYRMGPHTTSDDPTRYR A E E W ARDPI R R  L   G+  E    RV 
Sbjct: 247 PTFIEAITYRMGPHTTSDDPTRYRAAAETEIWKARDPIDRMRRLLDREGLLGEEFLARVQ 306

Query: 319 ARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELA 367
           A +  + A LR   V APD  P ++FD VY+   P +  +R+Q  + LA
Sbjct: 307 ATADAVAARLRSGTVEAPDPAPLDLFDHVYSTDHPLIDEEREQYAAYLA 355


>tr|D3LQ13|D3LQ13_MICLU Tax_Id=596312 SubName: Full=Dehydrogenase E1
           component;[Micrococcus luteus SK58]
          Length = 400

 Score =  305 bits (781), Expect = 6e-81
 Identities = 150/324 (46%), Positives = 213/324 (65%)

Query: 45  ETLSWLYESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYR 104
           E L   Y  +V+ R ++ +   L RQG +A++ S  GQEA+++ AA CL + DWLFP YR
Sbjct: 71  EELLAAYRHLVIGRRVNDQAYALVRQGRMAVYPSSHGQEASEVAAAVCLGEDDWLFPTYR 130

Query: 105 EIGAFLLRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGE 164
           +  A + RG+ P ++   ++G WH G       V+  + P+ T  LHAVG A AA+  GE
Sbjct: 131 DTVAVIARGVPPLEVMVAYQGTWHQGYDPRKHHVSIQSTPLTTQMLHAVGMAKAARLRGE 190

Query: 165 DSVTVAFLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRA 224
           + V +A +GDG TSEGD HEA N A VF+ P +FF+QNN++AISVP ++Q A P++AH+A
Sbjct: 191 EVVCLAMVGDGGTSEGDFHEALNFAAVFKLPVIFFVQNNKFAISVPFAKQSAAPSLAHKA 250

Query: 225 IGYGMPGIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPA 284
           +GYG+ G RVDGND+ A  AV+  A E  R+G+GP L+EA TYRM  HT +DDP+RYR  
Sbjct: 251 VGYGLAGERVDGNDLGALLAVLGRAVELCRQGQGPFLVEADTYRMQAHTNTDDPSRYRDD 310

Query: 285 EEVEAWAARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMF 344
            EV+ W ARDP+ R   YL++ G  TE +  ++A  +  +  +LRDA+    ++DP E+F
Sbjct: 311 AEVKEWEARDPLRRMTAYLESTGALTEEVSAQIARDAEDVAQQLRDAMNAETELDPLELF 370

Query: 345 DTVYADITPELARQRDQLLSELAK 368
           D VY+  TP+LA QR QL  EL++
Sbjct: 371 DHVYSVQTPQLAAQRAQLAEELSR 394


>tr|D6BAU5|D6BAU5_9ACTO Tax_Id=457425 SubName: Full=Branched-chain
           alpha-keto acid dehydrogenase E1-alpha
           subunit;[Streptomyces albus J1074]
          Length = 447

 Score =  305 bits (780), Expect = 8e-81
 Identities = 164/338 (48%), Positives = 200/338 (59%), Gaps = 1/338 (0%)

Query: 13  TGFDPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVNLQRQGE 72
           T  +P+ VQL+                     E L  LY  MV+TR  D E  +LQRQGE
Sbjct: 82  TPAEPQLVQLLTPEGKRVADAEYDPYVADITPEELRGLYRDMVLTRRFDAEATSLQRQGE 141

Query: 73  LALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHGGLS 132
           L L+AS  GQEAAQIG+    R+ DW+FP YRE G    RG+ PA +  ++RG  HGG  
Sbjct: 142 LGLWASLLGQEAAQIGSGRATREDDWVFPTYREHGVAWCRGVDPANLLGMFRGVNHGGWD 201

Query: 133 FTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLATVF 192
                     I IG+  LHA G AM   + G DS  +A+ GDGA+S+GD +EAF  + V+
Sbjct: 202 PNSNHFQLYTIVIGSQTLHATGYAMGITKDGADSAVIAYFGDGASSQGDVNEAFTFSAVY 261

Query: 193 RAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEAAER 252
            AP VFF QNNQWAIS P  +Q   P +  RA G+G PG+RVDGNDVLAC AV   A  R
Sbjct: 262 NAPVVFFCQNNQWAISEPTEKQTRVP-LYQRASGFGFPGVRVDGNDVLACLAVTKAALAR 320

Query: 253 ARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVWTER 312
           ARRGEGPTL+EA TYRMG HTTSDDPTRYR  +E E+W ARDPI R R +L+  G   E 
Sbjct: 321 ARRGEGPTLVEAFTYRMGAHTTSDDPTRYRSDDERESWEARDPIQRLRAHLEAEGHADEA 380

Query: 313 LEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYAD 350
               +   S  L   +R+A+   PD DP  MF+  YAD
Sbjct: 381 FFTALEEESEALGRRVREAVRAMPDPDPMAMFEHTYAD 418


>tr|A0JUQ5|A0JUQ5_ARTS2 Tax_Id=290399 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring);
           EC=1.2.4.1;[Arthrobacter sp.]
          Length = 392

 Score =  304 bits (779), Expect = 1e-80
 Identities = 173/361 (47%), Positives = 211/361 (58%), Gaps = 1/361 (0%)

Query: 7   SAPGYDTGFDPEPVQLVAAXXXXXXXXXXXXXXXXXXXETLSWLYESMVVTRNLDVEFVN 66
           ++ G+  G   + VQL+                     E L  LYE MVV R +D E   
Sbjct: 18  NSAGHHGGAGEDLVQLITPGGERVSHPQYDAWVRDVSDEQLGSLYEDMVVIRRIDTEATA 77

Query: 67  LQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGK 126
           LQRQGEL L+    GQEA+QIG+A  LR  D++F  YRE G    RG+  A +  VWRG 
Sbjct: 78  LQRQGELGLWPPLLGQEASQIGSARSLRDDDFVFSSYRENGVAYCRGVDLADILKVWRGN 137

Query: 127 WHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAF 186
              G       +A   I IG   LHA G AM  Q  G DSV + + GDGATSEGD +EA 
Sbjct: 138 ASAGWDPYTINMATPQIIIGAQTLHATGYAMGIQNDGADSVAITYFGDGATSEGDVNEAM 197

Query: 187 NLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVM 246
             A  F++P +FF QNN WAIS PV R Q+   IA RA G+G+PGIRVDGNDVLA  A  
Sbjct: 198 VFAASFQSPVIFFCQNNHWAISEPV-RLQSHIRIADRAAGFGIPGIRVDGNDVLAVMAAT 256

Query: 247 SEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNI 306
            EA ERAR G GPT IEAVTYRMGPHTT+DDPTRYR A E+E WAA+DPIAR R  L+  
Sbjct: 257 REALERARHGGGPTFIEAVTYRMGPHTTADDPTRYRDANELEDWAAKDPIARVRGLLERK 316

Query: 307 GVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSEL 366
           G+ T+ LE RVAA++  +  ++R   +  PD  P ++F  VY+     L RQ D     L
Sbjct: 317 GLLTDELEGRVAAKADAVARDMRAGCINMPDPQPLDIFKHVYSTPNSWLDRQEDHYSRYL 376

Query: 367 A 367
           A
Sbjct: 377 A 377


>tr|B8HEC4|B8HEC4_ARTCA Tax_Id=452863 SubName: Full=Pyruvate
           dehydrogenase (Acetyl-transferring); EC=1.2.4.1; Flags:
           Precursor;[Arthrobacter chlorophenolicus]
          Length = 409

 Score =  303 bits (775), Expect = 3e-80
 Identities = 153/320 (47%), Positives = 205/320 (64%)

Query: 51  YESMVVTRNLDVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFL 110
           YE +VV R ++ +   L RQG +A++ S  GQEA Q+ AA CL   DW+FP YR+  A +
Sbjct: 79  YEQLVVGRRVNDQNSALVRQGRMAVYPSSHGQEACQVAAALCLGDGDWMFPTYRDAVAVM 138

Query: 111 LRGITPAQMGAVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVA 170
            RG+ P Q+  ++RG WHGG       V   + P+ T  LHAVG A AA+  GED+V +A
Sbjct: 139 TRGVDPVQVMTIFRGDWHGGYDPLQYKVGIQSTPLTTQLLHAVGVAHAAKLRGEDTVVLA 198

Query: 171 FLGDGATSEGDAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMP 230
             GDGATSEGD HEA N A VF  P +FF+QNN++AISVP++ Q   P++AH+A+GYGM 
Sbjct: 199 MCGDGATSEGDFHEALNFAAVFHLPVIFFVQNNKYAISVPLAHQSVAPSLAHKAVGYGMA 258

Query: 231 GIRVDGNDVLACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAW 290
           G RVDGNDV+A  AV+  A    R G GP L+EA TYRM  HT +DD TRYR + EV  W
Sbjct: 259 GERVDGNDVVALLAVLDRAVALCRDGSGPLLVEANTYRMQAHTNADDDTRYRESAEVAEW 318

Query: 291 AARDPIARYRTYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYAD 350
            A+DP+ R RTYL   G+  +  E R+ A++  + A+LR+ +     VDP ++F  V+A 
Sbjct: 319 RAKDPVNRMRTYLTGQGILDDDGEARIRAKAESVAAQLREGLSEDVPVDPQDLFRHVFAV 378

Query: 351 ITPELARQRDQLLSELAKEA 370
            TP+L  Q   L  ELA++A
Sbjct: 379 QTPQLKEQSAFLADELARDA 398


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.320    0.134    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 2,971,168,381
Number of extensions: 117180452
Number of successful extensions: 286808
Number of sequences better than 10.0: 5309
Number of HSP's gapped: 283416
Number of HSP's successfully gapped: 5357
Length of query: 370
Length of database: 4,236,830,644
Length adjustment: 139
Effective length of query: 231
Effective length of database: 2,498,237,548
Effective search space: 577092873588
Effective search space used: 577092873588
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 81 (35.8 bits)