BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_4772 (503 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|A0R1J1|A0R1J1_MYCS2 Tax_Id=246196 SubName: Full=Acyl-CoA synt... 1002 0.0 tr|A3Q2R8|A3Q2R8_MYCSJ Tax_Id=164757 SubName: Full=AMP-dependent... 770 0.0 tr|Q1B5S2|Q1B5S2_MYCSS Tax_Id=164756 SubName: Full=AMP-dependent... 769 0.0 tr|A1UJB4|A1UJB4_MYCSK Tax_Id=189918 SubName: Full=AMP-dependent... 769 0.0 tr|A1TCL0|A1TCL0_MYCVP Tax_Id=350058 SubName: Full=AMP-dependent... 767 0.0 tr|A4T7Z4|A4T7Z4_MYCGI Tax_Id=350054 SubName: Full=AMP-dependent... 746 0.0 tr|Q742Q5|Q742Q5_MYCPA Tax_Id=1770 (fadD3)SubName: Full=FadD3_2;... 737 0.0 tr|A0QBE3|A0QBE3_MYCA1 Tax_Id=243243 SubName: Full=Acyl-CoA synt... 734 0.0 tr|A8L9J2|A8L9J2_FRASN Tax_Id=298653 SubName: Full=AMP-dependent... 724 0.0 tr|D3CZ66|D3CZ66_9ACTO Tax_Id=102897 SubName: Full=AMP-dependent... 716 0.0 tr|B2HFD0|B2HFD0_MYCMM Tax_Id=216594 (fadD3_2)SubName: Full=Fatt... 704 0.0 tr|D5PEI7|D5PEI7_9MYCO Tax_Id=525368 (fadD3_2)SubName: Full=Acyl... 701 0.0 tr|D1V692|D1V692_9ACTO Tax_Id=298654 SubName: Full=AMP-dependent... 655 0.0 tr|B5HL54|B5HL54_9ACTO Tax_Id=463191 SubName: Full=Acyl-CoA synt... 494 e-138 tr|Q82GU0|Q82GU0_STRAW Tax_Id=33903 (fadD16)SubName: Full=Putati... 492 e-137 tr|B5HKL7|B5HKL7_STRPR Tax_Id=457429 SubName: Full=Acyl-CoA synt... 491 e-136 tr|C9YV32|C9YV32_STRSW Tax_Id=680198 SubName: Full=Putative AMP-... 490 e-136 tr|B1W549|B1W549_STRGG Tax_Id=455632 SubName: Full=Putative fatt... 485 e-135 tr|D1XB68|D1XB68_9ACTO Tax_Id=649189 SubName: Full=AMP-dependent... 485 e-135 tr|D6ADT8|D6ADT8_STRFL Tax_Id=457431 SubName: Full=Acyl-CoA synt... 478 e-132 tr|B5GNI3|B5GNI3_STRCL Tax_Id=443255 SubName: Full=Acyl-CoA synt... 471 e-131 tr|B4V6W7|B4V6W7_9ACTO Tax_Id=465541 SubName: Full=Acyl-CoA synt... 471 e-130 tr|D1VMU0|D1VMU0_9ACTO Tax_Id=298654 SubName: Full=AMP-dependent... 466 e-129 tr|D3DB50|D3DB50_9ACTO Tax_Id=102897 SubName: Full=AMP-dependent... 463 e-128 tr|C7Q240|C7Q240_CATAD Tax_Id=479433 SubName: Full=AMP-dependent... 452 e-125 tr|A1SKD5|A1SKD5_NOCSJ Tax_Id=196162 SubName: Full=AMP-dependent... 450 e-124 tr|Q0K3I3|Q0K3I3_RALEH Tax_Id=381666 SubName: Full=Acyl-CoA synt... 449 e-124 tr|D1AB70|D1AB70_THECD Tax_Id=471852 SubName: Full=AMP-dependent... 445 e-123 tr|B2AIT8|B2AIT8_CUPTR Tax_Id=164546 SubName: Full=Putative fatt... 444 e-122 tr|A5VBI6|A5VBI6_SPHWW Tax_Id=392499 SubName: Full=AMP-dependent... 441 e-122 tr|A4XFB5|A4XFB5_NOVAD Tax_Id=279238 SubName: Full=AMP-dependent... 439 e-121 tr|Q471M0|Q471M0_RALEJ Tax_Id=264198 SubName: Full=AMP-dependent... 438 e-121 tr|D0J3C6|D0J3C6_COMT2 Tax_Id=688245 SubName: Full=Long-chain-fa... 434 e-119 tr|B7X423|B7X423_COMTE Tax_Id=399795 SubName: Full=AMP-dependent... 434 e-119 tr|A8M6H3|A8M6H3_SALAI Tax_Id=391037 SubName: Full=AMP-dependent... 428 e-118 tr|B4EKP2|B4EKP2_BURCJ Tax_Id=216591 SubName: Full=AMP-binding p... 427 e-117 tr|Q1B2T6|Q1B2T6_MYCSS Tax_Id=164756 SubName: Full=AMP-dependent... 427 e-117 tr|A3Q6R6|A3Q6R6_MYCSJ Tax_Id=164757 SubName: Full=AMP-dependent... 427 e-117 tr|A1UMB2|A1UMB2_MYCSK Tax_Id=189918 SubName: Full=AMP-dependent... 427 e-117 tr|A8H4F9|A8H4F9_SHEPA Tax_Id=398579 SubName: Full=AMP-dependent... 426 e-117 tr|Q7WSH3|Q7WSH3_COMTE Tax_Id=285 (ORF18)SubName: Full=ORF18 pro... 426 e-117 tr|Q396T0|Q396T0_BURS3 Tax_Id=269483 SubName: Full=AMP-dependent... 424 e-116 tr|C1BAT4|C1BAT4_RHOOB Tax_Id=632772 SubName: Full=Putative fatt... 424 e-116 tr|B7S1X5|B7S1X5_9GAMM Tax_Id=247634 (fadD)SubName: Full=AMP-bin... 424 e-116 tr|Q0S7V5|Q0S7V5_RHOSR Tax_Id=101510 SubName: Full=CoA ligase; E... 422 e-116 >tr|A0R1J1|A0R1J1_MYCS2 Tax_Id=246196 SubName: Full=Acyl-CoA synthase;[Mycobacterium smegmatis] Length = 503 Score = 1002 bits (2590), Expect = 0.0 Identities = 503/503 (100%), Positives = 503/503 (100%) Query: 1 MTHPSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLA 60 MTHPSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLA Sbjct: 1 MTHPSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLA 60 Query: 61 HGIGRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQ 120 HGIGRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQ Sbjct: 61 HGIGRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQ 120 Query: 121 QGFLGQDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNH 180 QGFLGQDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNH Sbjct: 121 QGFLGQDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNH 180 Query: 181 LQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIV 240 LQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIV Sbjct: 181 LQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIV 240 Query: 241 ELIATERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETV 300 ELIATERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETV Sbjct: 241 ELIATERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETV 300 Query: 301 ATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDP 360 ATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDP Sbjct: 301 ATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDP 360 Query: 361 AATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVA 420 AATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVA Sbjct: 361 AATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVA 420 Query: 421 QVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEE 480 QVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEE Sbjct: 421 QVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEE 480 Query: 481 LPLNATGKVMKDHLKAREALSKR 503 LPLNATGKVMKDHLKAREALSKR Sbjct: 481 LPLNATGKVMKDHLKAREALSKR 503 >tr|A3Q2R8|A3Q2R8_MYCSJ Tax_Id=164757 SubName: Full=AMP-dependent synthetase and ligase;[Mycobacterium sp.] Length = 483 Score = 770 bits (1988), Expect = 0.0 Identities = 387/492 (78%), Positives = 428/492 (86%), Gaps = 13/492 (2%) Query: 4 PSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGI 63 P W TIPEMVLSAADRFGDAEAVVD GPLR +F E+ R+R AAGAF GI Sbjct: 5 PKWSTIPEMVLSAADRFGDAEAVVD---------GPLRFSFAEVVHRIRCAAGAFADLGI 55 Query: 64 GRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGF 123 G+GDRVAIWAPNSAEW+IAAFG LTAGGV+VPVNTRFK+EEAADVI RSGAK VL QQGF Sbjct: 56 GKGDRVAIWAPNSAEWIIAAFGLLTAGGVLVPVNTRFKSEEAADVITRSGAKAVLVQQGF 115 Query: 124 LGQDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNHLQT 183 LG ++ P GVP I++KSDFLA GEP + G+DI+DI++TSGTTGRPKGVMMNH Q Sbjct: 116 LGVEYAAPEGVPVIDLKSDFLAGGEP-FSRTVDGSDISDIIFTSGTTGRPKGVMMNHRQN 174 Query: 184 LRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELI 243 LRLY EWC+LADLR+GDRYL+VNP+FHTFGYKAG IAS IRGAT++PV VFDVD +V+LI Sbjct: 175 LRLYEEWCNLADLRQGDRYLMVNPYFHTFGYKAGLIASFIRGATMVPVPVFDVDRVVDLI 234 Query: 244 ATERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATG 303 A ER+TMLPGPPTLYHSLL V DK+KLATLRAGVTGAADIPVEL+RR+ EELPF+T+ATG Sbjct: 235 AAERITMLPGPPTLYHSLLSVADKSKLATLRAGVTGAADIPVELVRRVLEELPFQTLATG 294 Query: 304 YGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAAT 363 YGLTEAGTATLSRPGDSF DIATTVGTACDGVEV +ADDGEVLVRGYSVMQGYLDDPAAT Sbjct: 295 YGLTEAGTATLSRPGDSFADIATTVGTACDGVEVRIADDGEVLVRGYSVMQGYLDDPAAT 354 Query: 364 AEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVA 423 AEAID GWLHTGDLG ++GRLRI+GRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQ A Sbjct: 355 AEAIDPHGWLHTGDLGTLDDAGRLRIVGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQAA 414 Query: 424 VIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPL 483 VIGV D+RMGQVGKAFVV RE G + ++AE LIAWSRERMAG+KVPRYVEFL+ELPL Sbjct: 415 VIGVPDERMGQVGKAFVVRRE---GHAEPLSAEGLIAWSRERMAGFKVPRYVEFLDELPL 471 Query: 484 NATGKVMKDHLK 495 NATGKVMKD L+ Sbjct: 472 NATGKVMKDQLR 483 >tr|Q1B5S2|Q1B5S2_MYCSS Tax_Id=164756 SubName: Full=AMP-dependent synthetase and ligase;[Mycobacterium sp.] Length = 483 Score = 769 bits (1986), Expect = 0.0 Identities = 387/492 (78%), Positives = 427/492 (86%), Gaps = 13/492 (2%) Query: 4 PSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGI 63 P W TIPEMVLSAADRFGDAEAVVD GPLRL+F E+ R+R AAGAF GI Sbjct: 5 PKWSTIPEMVLSAADRFGDAEAVVD---------GPLRLSFAEVVHRIRCAAGAFADLGI 55 Query: 64 GRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGF 123 G+GDRVAIWAPNSAEW+IAAFG LTAGGV+VPVNTRFK EEAADVI RSGA+ VL QQGF Sbjct: 56 GKGDRVAIWAPNSAEWIIAAFGLLTAGGVLVPVNTRFKGEEAADVITRSGARAVLVQQGF 115 Query: 124 LGQDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNHLQT 183 LG ++ P GVP I++KSDFLA GEP + +DI+DI++TSGTTGRPKGVMMNH Q Sbjct: 116 LGVEYAAPEGVPVIDLKSDFLAGGEP-FSRTVDSSDISDIIFTSGTTGRPKGVMMNHRQN 174 Query: 184 LRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELI 243 LRLY EWC+LADLR+GDRYL+VNP+FHTFGYKAG IAS IRGAT++PV VFDVD +V+LI Sbjct: 175 LRLYEEWCNLADLRQGDRYLMVNPYFHTFGYKAGLIASFIRGATMVPVPVFDVDRVVDLI 234 Query: 244 ATERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATG 303 A ER+TMLPGPPTLYHSLL V DK+KLATLRAGVTGAADIPVEL+RR+ EELPF+T+ATG Sbjct: 235 AAERITMLPGPPTLYHSLLSVADKSKLATLRAGVTGAADIPVELVRRVLEELPFQTLATG 294 Query: 304 YGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAAT 363 YGLTEAGTATLSRPGDSF DIATTVGTACDGVEV +ADDGEVLVRGYSVMQGYLDDPAAT Sbjct: 295 YGLTEAGTATLSRPGDSFADIATTVGTACDGVEVRIADDGEVLVRGYSVMQGYLDDPAAT 354 Query: 364 AEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVA 423 AEAID DGWLHTGDLG ++GRLRI+GRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQ A Sbjct: 355 AEAIDPDGWLHTGDLGTLDDAGRLRIVGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQAA 414 Query: 424 VIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPL 483 VIGV D+RMGQVGKAFVV R DG ++AE LIAWSRERMAG+KVPRYVEFL+ELPL Sbjct: 415 VIGVPDERMGQVGKAFVVRR---DGHAGPLSAEGLIAWSRERMAGFKVPRYVEFLDELPL 471 Query: 484 NATGKVMKDHLK 495 NATGKVMKD L+ Sbjct: 472 NATGKVMKDQLR 483 >tr|A1UJB4|A1UJB4_MYCSK Tax_Id=189918 SubName: Full=AMP-dependent synthetase and ligase;[Mycobacterium sp.] Length = 483 Score = 769 bits (1986), Expect = 0.0 Identities = 387/492 (78%), Positives = 427/492 (86%), Gaps = 13/492 (2%) Query: 4 PSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGI 63 P W TIPEMVLSAADRFGDAEAVVD GPLRL+F E+ R+R AAGAF GI Sbjct: 5 PKWSTIPEMVLSAADRFGDAEAVVD---------GPLRLSFAEVVHRIRCAAGAFADLGI 55 Query: 64 GRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGF 123 G+GDRVAIWAPNSAEW+IAAFG LTAGGV+VPVNTRFK EEAADVI RSGA+ VL QQGF Sbjct: 56 GKGDRVAIWAPNSAEWIIAAFGLLTAGGVLVPVNTRFKGEEAADVITRSGARAVLVQQGF 115 Query: 124 LGQDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNHLQT 183 LG ++ P GVP I++KSDFLA GEP + +DI+DI++TSGTTGRPKGVMMNH Q Sbjct: 116 LGVEYAAPEGVPVIDLKSDFLAGGEP-FSRTVDSSDISDIIFTSGTTGRPKGVMMNHRQN 174 Query: 184 LRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELI 243 LRLY EWC+LADLR+GDRYL+VNP+FHTFGYKAG IAS IRGAT++PV VFDVD +V+LI Sbjct: 175 LRLYEEWCNLADLRQGDRYLMVNPYFHTFGYKAGLIASFIRGATMVPVPVFDVDRVVDLI 234 Query: 244 ATERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATG 303 A ER+TMLPGPPTLYHSLL V DK+KLATLRAGVTGAADIPVEL+RR+ EELPF+T+ATG Sbjct: 235 AAERITMLPGPPTLYHSLLSVADKSKLATLRAGVTGAADIPVELVRRVLEELPFQTLATG 294 Query: 304 YGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAAT 363 YGLTEAGTATLSRPGDSF DIATTVGTACDGVEV +ADDGEVLVRGYSVMQGYLDDPAAT Sbjct: 295 YGLTEAGTATLSRPGDSFADIATTVGTACDGVEVRIADDGEVLVRGYSVMQGYLDDPAAT 354 Query: 364 AEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVA 423 AEAID DGWLHTGDLG ++GRLRI+GRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQ A Sbjct: 355 AEAIDPDGWLHTGDLGTLDDAGRLRIVGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQAA 414 Query: 424 VIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPL 483 VIGV D+RMGQVGKAFVV R DG ++AE LIAWSRERMAG+KVPRYVEFL+ELPL Sbjct: 415 VIGVPDERMGQVGKAFVVRR---DGHAGPLSAEGLIAWSRERMAGFKVPRYVEFLDELPL 471 Query: 484 NATGKVMKDHLK 495 NATGKVMKD L+ Sbjct: 472 NATGKVMKDQLR 483 >tr|A1TCL0|A1TCL0_MYCVP Tax_Id=350058 SubName: Full=AMP-dependent synthetase and ligase;[Mycobacterium vanbaalenii] Length = 490 Score = 767 bits (1981), Expect = 0.0 Identities = 378/494 (76%), Positives = 426/494 (86%), Gaps = 10/494 (2%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 WQTIPEMV SAADRFGDAEAVVD GPLRL+F EL +R+ AAGAF GI + Sbjct: 7 WQTIPEMVASAADRFGDAEAVVD---------GPLRLSFTELVERISCAAGAFAELGIEK 57 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDR AIWAPNSAEW+IAAFG LTAGGV+VPVNTRFK +EAAD+I RSGAK VL QQGFLG Sbjct: 58 GDRAAIWAPNSAEWIIAAFGLLTAGGVLVPVNTRFKTDEAADIIARSGAKAVLVQQGFLG 117 Query: 126 QDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNHLQTLR 185 D+ P GVP I+++SDFL+SG P ++GTD++DI++TSGTTGRPKGVMMNH Q LR Sbjct: 118 VDYTAPGGVPVIDLRSDFLSSGTP-FSRPVQGTDVSDIIFTSGTTGRPKGVMMNHRQNLR 176 Query: 186 LYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIAT 245 LY EWCDLADLR+GDRYL+VNP+FHTFGYKAG IAS IRGAT+LPV+VFDVD +VELIA Sbjct: 177 LYQEWCDLADLRQGDRYLMVNPYFHTFGYKAGLIASFIRGATMLPVSVFDVDRVVELIAA 236 Query: 246 ERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATGYG 305 ER+TMLPGPPTLYHSLL V DK+KLATLRAGVTGAADIPVEL+RR+HEELPF+T+ATGYG Sbjct: 237 ERITMLPGPPTLYHSLLNVTDKSKLATLRAGVTGAADIPVELVRRVHEELPFQTLATGYG 296 Query: 306 LTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAATAE 365 LTEAGT TLSRPGDSFTDIATT G ACDGVE+ +ADDGEVLVRGY+VMQGYLDDP ATAE Sbjct: 297 LTEAGTVTLSRPGDSFTDIATTAGVACDGVEMRIADDGEVLVRGYTVMQGYLDDPVATAE 356 Query: 366 AIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVI 425 ID DGWLHTGDLG ++GRLRI+GRKKDMFIVGGFNAYPAEIEGFLLEH VAQ AVI Sbjct: 357 TIDPDGWLHTGDLGTVDDAGRLRIVGRKKDMFIVGGFNAYPAEIEGFLLEHRAVAQAAVI 416 Query: 426 GVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNA 485 GV D+R+GQVGKAFVV + P DG+ +TAE LIAW R+RMAG+KVPRYVEFL+ELPLNA Sbjct: 417 GVPDERLGQVGKAFVVAKTPADGSGAALTAEGLIAWCRDRMAGFKVPRYVEFLDELPLNA 476 Query: 486 TGKVMKDHLKAREA 499 TGKVMKD L+ R++ Sbjct: 477 TGKVMKDRLQNRQS 490 >tr|A4T7Z4|A4T7Z4_MYCGI Tax_Id=350054 SubName: Full=AMP-dependent synthetase and ligase;[Mycobacterium gilvum] Length = 478 Score = 746 bits (1926), Expect = 0.0 Identities = 370/483 (76%), Positives = 413/483 (85%), Gaps = 10/483 (2%) Query: 12 MVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGDRVAI 71 MV SAADRFGDAEAVVD G LRL+F ++ +R+R AAGAF GIG+GDR AI Sbjct: 1 MVASAADRFGDAEAVVD---------GSLRLSFDDVVERIRCAAGAFADLGIGKGDRAAI 51 Query: 72 WAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQDFEVP 131 WAPNS EW++AAFG LTAGGV+VPVNTRFKA+EAAD+I RSGAK VL QGFLG D+ P Sbjct: 52 WAPNSVEWIVAAFGLLTAGGVLVPVNTRFKADEAADIISRSGAKAVLVHQGFLGVDYRAP 111 Query: 132 AGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWC 191 GVP I++KSDFLASG P ++GTD++DI++TSGTTGRPKGVMMNH Q LRLY EWC Sbjct: 112 QGVPVIDLKSDFLASGTP-FSRPVQGTDVSDIIFTSGTTGRPKGVMMNHQQNLRLYEEWC 170 Query: 192 DLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIATERVTML 251 DLADLREGDRYL+VNP+FHTFGYKAG IAS IRGAT+ PV VFDVD +VELIA ER+TML Sbjct: 171 DLADLREGDRYLMVNPYFHTFGYKAGLIASFIRGATMFPVPVFDVDRVVELIAAERITML 230 Query: 252 PGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATGYGLTEAGT 311 PGPPTLYHSLL V DK++LATLRAGVTGAADIPVELIRR+HEELPF+T+ATGYGLTEAGT Sbjct: 231 PGPPTLYHSLLAVKDKSRLATLRAGVTGAADIPVELIRRVHEELPFQTLATGYGLTEAGT 290 Query: 312 ATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAATAEAIDADG 371 ATLSRPGDSF DIATT G ACDGVE+ +A+DGEVL+RGY+VMQGYLDDP ATAEAID DG Sbjct: 291 ATLSRPGDSFDDIATTAGVACDGVELRIAEDGEVLIRGYTVMQGYLDDPDATAEAIDPDG 350 Query: 372 WLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDR 431 WLHTGDLG E+GRLRI+GRKKDMFIVGGFNAYPAEIEGFLLEHP VAQ AV+GV D+R Sbjct: 351 WLHTGDLGTLDEAGRLRIVGRKKDMFIVGGFNAYPAEIEGFLLEHPGVAQAAVVGVPDER 410 Query: 432 MGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMK 491 MGQVGKAFVV P DG+ + A LIAW RERMAG+KVPRYVEFL+ELPLNATGKVMK Sbjct: 411 MGQVGKAFVVAAAPADGSAGSLDAHALIAWCRERMAGFKVPRYVEFLDELPLNATGKVMK 470 Query: 492 DHL 494 D L Sbjct: 471 DRL 473 >tr|Q742Q5|Q742Q5_MYCPA Tax_Id=1770 (fadD3)SubName: Full=FadD3_2;[Mycobacterium paratuberculosis] Length = 478 Score = 737 bits (1903), Expect = 0.0 Identities = 367/495 (74%), Positives = 412/495 (83%), Gaps = 17/495 (3%) Query: 1 MTHPSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLA 60 M P WQTIPEMVLSAADRFGDAEAVVD GPLRLTF ++ +R+R AAGAF Sbjct: 1 MNSPRWQTIPEMVLSAADRFGDAEAVVD---------GPLRLTFQQVVERIRCAAGAFAE 51 Query: 61 HGIGRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQ 120 G+ +GDRVA+WAPNSAEW+IAAFG LTAGGV+VPVNTRFK EEAAD+I R+ K VL Q Sbjct: 52 LGVEKGDRVAVWAPNSAEWIIAAFGLLTAGGVLVPVNTRFKTEEAADIIVRARVKAVLVQ 111 Query: 121 QGFLGQDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNH 180 +GFLGQD+ PAG+P I+IKSDFL+SG P + GTDI+DI++TSGTTGRPKG MMNH Sbjct: 112 KGFLGQDYAAPAGIPVIDIKSDFLSSGSP-FSRPVNGTDISDIIFTSGTTGRPKGAMMNH 170 Query: 181 LQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIV 240 QTLR+Y EW LADLREGDRYL +NP+FHTFG KAG I S +RGAT+LPV VFDVD +V Sbjct: 171 RQTLRMYDEWATLADLREGDRYLQINPYFHTFGLKAGLITSFLRGATMLPVPVFDVDTVV 230 Query: 241 ELIATERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETV 300 +LI ER+TMLPGPPTLYHSLL VPDK+KLATLRAGVTGAADIPVEL+RRIH+ELPF+T+ Sbjct: 231 DLIERERITMLPGPPTLYHSLLTVPDKSKLATLRAGVTGAADIPVELVRRIHDELPFQTL 290 Query: 301 ATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDP 360 TGYGLTEAG TLSRPGDSF D+ATT G C+GVEV +ADDGEVLVRGY VMQGYLDDP Sbjct: 291 MTGYGLTEAGNVTLSRPGDSFEDVATTAGVPCEGVEVRIADDGEVLVRGYGVMQGYLDDP 350 Query: 361 AATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVA 420 A TAEAIDADGWLHTGDLG FTE+GRLRI+GRKKDMFIVGGFNAYPAEIEGFLL HP VA Sbjct: 351 AGTAEAIDADGWLHTGDLGTFTETGRLRIVGRKKDMFIVGGFNAYPAEIEGFLLNHPAVA 410 Query: 421 QVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEE 480 Q AVIGV D+RMGQVGKAFVV V+ DL+AW R+RMAG+KVPR VEFL+ Sbjct: 411 QAAVIGVPDERMGQVGKAFVVANAE-------VSESDLLAWCRDRMAGFKVPRTVEFLDA 463 Query: 481 LPLNATGKVMKDHLK 495 LPLNATGKVMKD L+ Sbjct: 464 LPLNATGKVMKDQLR 478 >tr|A0QBE3|A0QBE3_MYCA1 Tax_Id=243243 SubName: Full=Acyl-CoA synthase;[Mycobacterium avium] Length = 491 Score = 734 bits (1896), Expect = 0.0 Identities = 365/495 (73%), Positives = 412/495 (83%), Gaps = 17/495 (3%) Query: 1 MTHPSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLA 60 + P WQTIPEMVLSAADRFGDAEAVVD GPLRLTF ++ +R+R AAGAF Sbjct: 14 LNSPRWQTIPEMVLSAADRFGDAEAVVD---------GPLRLTFQQVVERIRCAAGAFAE 64 Query: 61 HGIGRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQ 120 G+ +GDRVA+WAPNSAEW+IAAFG LTAGGV+VPVNTRFK EEAAD+I R+ + VL Q Sbjct: 65 LGVEKGDRVAVWAPNSAEWIIAAFGLLTAGGVLVPVNTRFKTEEAADIIVRARVQAVLVQ 124 Query: 121 QGFLGQDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNH 180 +GFLGQD+ PAG+P I+IKSDFL+SG P + GTDI+DI++TSGTTGRPKG MMNH Sbjct: 125 KGFLGQDYAAPAGIPVIDIKSDFLSSGSP-FSRPVNGTDISDIIFTSGTTGRPKGAMMNH 183 Query: 181 LQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIV 240 QTLR+Y EW LADLREGDRYL +NP+FHTFG KAG I S +RGAT+LPV VFDVD +V Sbjct: 184 RQTLRMYDEWATLADLREGDRYLQINPYFHTFGLKAGLITSFLRGATMLPVPVFDVDTVV 243 Query: 241 ELIATERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETV 300 +LI ER+TMLPGPPTLYHSLL VPDK+KLATLRAGVTGAADIPVEL+RRIH+ELPF+T+ Sbjct: 244 DLIERERITMLPGPPTLYHSLLTVPDKSKLATLRAGVTGAADIPVELVRRIHDELPFQTL 303 Query: 301 ATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDP 360 TGYGLTEAG TLSRPGDSF D+ATT G C+GVEV +ADDGEVLVRGY VMQGYLDDP Sbjct: 304 MTGYGLTEAGNVTLSRPGDSFEDVATTAGVPCEGVEVRIADDGEVLVRGYGVMQGYLDDP 363 Query: 361 AATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVA 420 A TAEAIDADGWLHTGDLG FTE+GRLRI+GRKKDMFIVGGFNAYPAEIEGFLL HP VA Sbjct: 364 AGTAEAIDADGWLHTGDLGTFTETGRLRIVGRKKDMFIVGGFNAYPAEIEGFLLNHPAVA 423 Query: 421 QVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEE 480 Q AVIGV D+RMGQVGKAFVV V+ DL+AW R+RMAG+KVPR VEFL+ Sbjct: 424 QAAVIGVPDERMGQVGKAFVVANAE-------VSESDLLAWCRDRMAGFKVPRTVEFLDA 476 Query: 481 LPLNATGKVMKDHLK 495 LPLNATGKVMKD L+ Sbjct: 477 LPLNATGKVMKDQLR 491 >tr|A8L9J2|A8L9J2_FRASN Tax_Id=298653 SubName: Full=AMP-dependent synthetase and ligase;[Frankia sp.] Length = 477 Score = 724 bits (1870), Expect = 0.0 Identities = 362/491 (73%), Positives = 413/491 (84%), Gaps = 17/491 (3%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W+TIPEMVLSAADRF DAEAVVD G LRLT+ EL DR+R AAG+F A G+G+ Sbjct: 3 WETIPEMVLSAADRFDDAEAVVD---------GALRLTYTELVDRIRAAAGSFAAAGVGK 53 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVAIWAPNSAEW+IAAFG LTAGGV+VPVNTR+KAEEA D++RRSGAK+VL Q+GFLG Sbjct: 54 GDRVAIWAPNSAEWIIAAFGLLTAGGVLVPVNTRYKAEEADDILRRSGAKMVLVQEGFLG 113 Query: 126 QDFEVPAGVPAIEIKSDFLASGEPAVVG-GLRGTDIADIVYTSGTTGRPKGVMMNHLQTL 184 Q + VPA++IKS FL+SG P G G + ADI++TSGTTGRPKGVMMNH QTL Sbjct: 114 QVYAGTTCVPAVDIKSGFLSSGAPLDGPVGQDGDETADILFTSGTTGRPKGVMMNHRQTL 173 Query: 185 RLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIA 244 RLY EWC+LADLREGDRYL VNPFFH FGYKAG +A+LIRGAT++P+AVF++D ++EL+ Sbjct: 174 RLYEEWCELADLREGDRYLCVNPFFHNFGYKAGLVAALIRGATIVPMAVFEIDKLIELVE 233 Query: 245 TERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATGY 304 E++TMLPGPPTLYHSLL VPDK LA+LR VTG+ADIPVELIRR+ +ELPF ++ TGY Sbjct: 234 REKITMLPGPPTLYHSLLAVPDKTALASLRCAVTGSADIPVELIRRMRDELPFRSIMTGY 293 Query: 305 GLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAATA 364 GLTEAGTAT SRPGDSF DIATTVGTACDGVEV +ADDGEVLVRGY+VMQGYLDDP ATA Sbjct: 294 GLTEAGTATASRPGDSFVDIATTVGTACDGVEVAVADDGEVLVRGYTVMQGYLDDPVATA 353 Query: 365 EAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAV 424 EAID DGWLHTGDLG E G LRI+GRKKDMFIVGGFNAYPAEIEGFLLEHP VAQ AV Sbjct: 354 EAIDPDGWLHTGDLGTLDERGHLRIVGRKKDMFIVGGFNAYPAEIEGFLLEHPAVAQAAV 413 Query: 425 IGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLN 484 IGV D+RMG+VGKAFVV R P VTA++LI WS+ RMAG+KVPR VEFLE LPLN Sbjct: 414 IGVPDERMGEVGKAFVVRRAP-------VTADELITWSKGRMAGFKVPRTVEFLESLPLN 466 Query: 485 ATGKVMKDHLK 495 A+GKVMKD+L+ Sbjct: 467 ASGKVMKDNLR 477 >tr|D3CZ66|D3CZ66_9ACTO Tax_Id=102897 SubName: Full=AMP-dependent synthetase and ligase;[Frankia sp. EUN1f] Length = 477 Score = 716 bits (1848), Expect = 0.0 Identities = 361/491 (73%), Positives = 412/491 (83%), Gaps = 17/491 (3%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W+TIPEMVLSAADRFGDAEAVVD G LRLT+ +L RVR AAG+F A G+G+ Sbjct: 3 WETIPEMVLSAADRFGDAEAVVD---------GALRLTYTDLVGRVRTAAGSFAAAGVGK 53 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVAIWAPNSAEW+IAAFG LTAGGV+VPVNTR+KAEEA D++ RSGAK+VL Q+GFLG Sbjct: 54 GDRVAIWAPNSAEWIIAAFGLLTAGGVLVPVNTRYKAEEANDILTRSGAKMVLVQEGFLG 113 Query: 126 QDFEVPAGVPAIEIKSDFLASGEPAVVGGLR-GTDIADIVYTSGTTGRPKGVMMNHLQTL 184 Q + VPA++IKS FL SG P + G DIADI++TSGTTGRPKGVMMNH QTL Sbjct: 114 QAYTGITAVPAVDIKSGFLTSGAPLDAPVVTDGDDIADILFTSGTTGRPKGVMMNHHQTL 173 Query: 185 RLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIA 244 RLYAEWC ADLREGDRYLIVNPFFH FGYKAG +A+LIRGAT++PVAV ++D ++ELI Sbjct: 174 RLYAEWCCQADLREGDRYLIVNPFFHNFGYKAGIVAALIRGATIVPVAVLEMDRLLELIE 233 Query: 245 TERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATGY 304 ER+TMLPGPPTLYHSLL A +++LR VTG+ADIPVELIRR+ +ELPF+++ TGY Sbjct: 234 RERITMLPGPPTLYHSLLAARGSADVSSLRCAVTGSADIPVELIRRMKQELPFQSIMTGY 293 Query: 305 GLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAATA 364 GLTEAGTAT SRPGDSF DIATTVG ACDGVE+++ADDGEVL+RGY+VMQGYLDDPAATA Sbjct: 294 GLTEAGTATASRPGDSFEDIATTVGKACDGVEISIADDGEVLIRGYTVMQGYLDDPAATA 353 Query: 365 EAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAV 424 EAID DGWLHTGDLG E G LRIIGRKKDMFIVGGFNAYPAEIEGFLL HP VAQVAV Sbjct: 354 EAIDPDGWLHTGDLGTLDERGYLRIIGRKKDMFIVGGFNAYPAEIEGFLLGHPAVAQVAV 413 Query: 425 IGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLN 484 IGV DDR+G+VGKAFVV R P VTA++LIAWSRE+MAG+KVPR+VEFLE LPLN Sbjct: 414 IGVPDDRLGEVGKAFVVRRGP-------VTADELIAWSREKMAGFKVPRHVEFLESLPLN 466 Query: 485 ATGKVMKDHLK 495 A+GKVMKD L+ Sbjct: 467 ASGKVMKDQLR 477 >tr|B2HFD0|B2HFD0_MYCMM Tax_Id=216594 (fadD3_2)SubName: Full=Fatty-acid-CoA ligase FadD3_2;[Mycobacterium marinum] Length = 479 Score = 704 bits (1817), Expect = 0.0 Identities = 349/490 (71%), Positives = 406/490 (82%), Gaps = 14/490 (2%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 WQTIPEMVLSA +RFGDAEA+VD G LR+TF EL +RV RAAGAF A GI + Sbjct: 4 WQTIPEMVLSAGERFGDAEAIVD---------GSLRITFTELTNRVHRAAGAFAAMGIDK 54 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVA+WAPNSAEW+IAAFG LTAG V+VPVNTRFK +EAAD+IRRSGA+ VL ++GFLG Sbjct: 55 GDRVAVWAPNSAEWIIAAFGLLTAGAVLVPVNTRFKTDEAADIIRRSGARAVLFEKGFLG 114 Query: 126 QDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNHLQTLR 185 DF VP G+PAI+++S FL G+P + G+DIADIVYTSGTTGRPKGVMM+H QTLR Sbjct: 115 MDFTVPDGIPAIDLRSGFLECGKP-FERAVSGSDIADIVYTSGTTGRPKGVMMDHAQTLR 173 Query: 186 LYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIAT 245 YA WCD ADLR GDRYLIVNPFFH FGYKAGCIASLIRGAT++PV VF ++ ++ELI Sbjct: 174 HYAHWCDRADLRTGDRYLIVNPFFHIFGYKAGCIASLIRGATIIPVRVFVLENVLELIEH 233 Query: 246 ERVTMLPGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATGYG 305 ER+TMLPGPPTLYHSLL + L++LRAGVTGAADIPVELIRR+ ELPF+T+ TGYG Sbjct: 234 ERITMLPGPPTLYHSLLSARGQRDLSSLRAGVTGAADIPVELIRRVRTELPFQTIMTGYG 293 Query: 306 LTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAATAE 365 LTEAGT TLS+P DSF DIATT G ACDG+E+ ADDGE+LVRGY+VM+GYLDDP ATAE Sbjct: 294 LTEAGTVTLSKPEDSFEDIATTAGLACDGIELATADDGEILVRGYNVMKGYLDDPVATAE 353 Query: 366 AIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVI 425 AID +GWLHTGDLG E+GRLR++GRKKDMFIVGGFNAYPAEIEGFL+EH VAQVAVI Sbjct: 354 AIDGEGWLHTGDLGTIDETGRLRVVGRKKDMFIVGGFNAYPAEIEGFLMEHEAVAQVAVI 413 Query: 426 GVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNA 485 GV D+R+GQVGKAFVV + + ++AEDL+ W RERMAG+KVPR V F++ LPLNA Sbjct: 414 GVPDERLGQVGKAFVVRQ----SGKSALSAEDLLGWCRERMAGFKVPRSVRFVDALPLNA 469 Query: 486 TGKVMKDHLK 495 TGKV+KD L+ Sbjct: 470 TGKVVKDLLR 479 >tr|D5PEI7|D5PEI7_9MYCO Tax_Id=525368 (fadD3_2)SubName: Full=Acyl-CoA synthetase; EC=2.3.1.86;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 467 Score = 701 bits (1809), Expect = 0.0 Identities = 349/484 (72%), Positives = 399/484 (82%), Gaps = 17/484 (3%) Query: 12 MVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGDRVAI 71 MV +AADRFGDAEA+VD GPLRLTF E +R+R AAGAF GI +GDRVAI Sbjct: 1 MVSTAADRFGDAEAIVD---------GPLRLTFSEAVERIRCAAGAFAGLGIDKGDRVAI 51 Query: 72 WAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQDFEVP 131 WAPNSAEW++AAFG LTAGGV+VPVNTRFKA+EA D+I RS A+ V+ Q+GFLGQ++ P Sbjct: 52 WAPNSAEWIVAAFGLLTAGGVLVPVNTRFKADEAGDIITRSKARAVMVQKGFLGQEYTAP 111 Query: 132 AGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWC 191 AG+P I++KSDFL+ G P + G DIAD+++TSGTTGRPKG MMNH QTLR+Y EW Sbjct: 112 AGIPVIDLKSDFLSGGAP-FERAVSGDDIADVIFTSGTTGRPKGAMMNHRQTLRMYEEWA 170 Query: 192 DLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIATERVTML 251 LADLREGDRYL VNP+FHTFG KAG + S +RGAT+LPV VFDV +V+LI ERVTML Sbjct: 171 TLADLREGDRYLQVNPYFHTFGLKAGLVTSFLRGATMLPVPVFDVGEVVDLIERERVTML 230 Query: 252 PGPPTLYHSLLGVPDKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATGYGLTEAGT 311 PGPPTLYHSLL VPDKAKL++LRAGVTGAADIPVEL+RRIH ELPF+T+ TGYGLTEAG Sbjct: 231 PGPPTLYHSLLTVPDKAKLSSLRAGVTGAADIPVELVRRIHGELPFQTLMTGYGLTEAGN 290 Query: 312 ATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDPAATAEAIDADG 371 TLSRPGDSF D+ATT G CDGVEV +ADDGEVLVRGY VMQGYLDDP TA AIDADG Sbjct: 291 VTLSRPGDSFEDVATTAGLPCDGVEVRIADDGEVLVRGYGVMQGYLDDPEGTAAAIDADG 350 Query: 372 WLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDR 431 WLHTGDLG ++GRLRI+GRKKDMFIVGGFNAYPAEIEGFL+ HP VAQ AVIGV D+R Sbjct: 351 WLHTGDLGNLDDAGRLRIVGRKKDMFIVGGFNAYPAEIEGFLMHHPAVAQAAVIGVPDER 410 Query: 432 MGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMK 491 +GQVGKAFVV ++ VTAE+LIAW RERMAG+KVPR VEFL+ LPLNATGKV+K Sbjct: 411 LGQVGKAFVVAKD-------AVTAEELIAWCRERMAGFKVPRSVEFLDVLPLNATGKVVK 463 Query: 492 DHLK 495 D L+ Sbjct: 464 DLLR 467 >tr|D1V692|D1V692_9ACTO Tax_Id=298654 SubName: Full=AMP-dependent synthetase and ligase;[Frankia sp. EuI1c] Length = 506 Score = 655 bits (1689), Expect = 0.0 Identities = 330/495 (66%), Positives = 391/495 (78%), Gaps = 20/495 (4%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W TIPEMVLS A RFGDAEA+VD G LRLT+V+ +RVR AAGAF G+ Sbjct: 27 WDTIPEMVLSTATRFGDAEALVD---------GDLRLTYVQFTERVRAAAGAFAELGVEA 77 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVA+WAPNSAEW IAAFG LTAGGV+VPVNTR+KA EAAD+I RSGAK VL Q GFLG Sbjct: 78 GDRVALWAPNSAEWAIAAFGLLTAGGVLVPVNTRYKAAEAADIIVRSGAKAVLTQPGFLG 137 Query: 126 QDFEVPAGVPAIEIKSDFLASGEPAVVGGLRGTDIADIVYTSGTTGRPKGVMMNHLQTLR 185 D+E+PAGV +++KSDFL SG P + G DIADI++TSGTTGRPKGVMMNH QTLR Sbjct: 138 IDYEIPAGVTGVDLKSDFLTSGSP-FERKVDGGDIADIIFTSGTTGRPKGVMMNHRQTLR 196 Query: 186 LYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIAT 245 LY+EW A L EGDRYL++NP+FHTFG KAG IASLI+GAT+ P+AVFDV + E++ Sbjct: 197 LYSEWTYQAQLGEGDRYLMINPYFHTFGLKAGLIASLIKGATMFPLAVFDVATVAEIVER 256 Query: 246 ERVTMLPGPPTLYHSLLGVPDKAKLA-----TLRAGVTGAADIPVELIRRIHEELPFETV 300 E++TMLPG PT+Y SLL ++A +LR VTG+ADIPVELIRR+ +ELPF+ + Sbjct: 257 EKITMLPGAPTVYQSLLEAIGSGQIAGRDLSSLRCAVTGSADIPVELIRRMKQELPFQHI 316 Query: 301 ATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVMQGYLDDP 360 TGYGLTEAGTAT SRPGDSF DIATTVG CDG+EV +A D EVL+RGYSVMQGY ++P Sbjct: 317 MTGYGLTEAGTATASRPGDSFEDIATTVGAPCDGIEVAIAGDSEVLIRGYSVMQGYFENP 376 Query: 361 AATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVA 420 AAT + IDADGWLHTGDLG + G ++IIGRKKDMFIVGGFNAYPAEIEG+LLEHP +A Sbjct: 377 AATTDTIDADGWLHTGDLGSMDDRGYVKIIGRKKDMFIVGGFNAYPAEIEGYLLEHPAIA 436 Query: 421 QVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEE 480 Q AVIGV D RMG+V KAF+V R + VTA+++IAWS+ERMAG+K PR+VEFL+ Sbjct: 437 QAAVIGVPDARMGEVCKAFLVKRSGAE-----VTADEIIAWSKERMAGFKAPRFVEFLDA 491 Query: 481 LPLNATGKVMKDHLK 495 LPLNATGKV+KD L+ Sbjct: 492 LPLNATGKVVKDQLR 506 >tr|B5HL54|B5HL54_9ACTO Tax_Id=463191 SubName: Full=Acyl-CoA synthetase;[Streptomyces sviceus ATCC 29083] Length = 516 Score = 494 bits (1273), Expect = e-138 Identities = 276/526 (52%), Positives = 345/526 (65%), Gaps = 50/526 (9%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W++IPE+V AA+R+ EAVV+ G R+T+ EL RV RAA A LA+G+ Sbjct: 3 WRSIPELVGWAAERYAGTEAVVE---------GRNRVTYAELGARVERAAAACLANGVQA 53 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVA+WAPNS +WM++A GA++ G V+VP+NTRFK EAADV+RRSG +++ FLG Sbjct: 54 GDRVAVWAPNSLDWMVSALGAVSVGAVLVPLNTRFKGTEAADVLRRSGTRLLFVTGTFLG 113 Query: 126 QDFEVPA--------GVPAIE--------------IKSDFLASGEPAVVGGLRGTDIA-- 161 + G+P +E DFLASG+ +R + Sbjct: 114 TSYVASLRRAVAQGPGLPDLEQVVVLSDDAPADYRTWKDFLASGDGVGAAEVRARADSVT 173 Query: 162 -----DIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKA 216 DIV+TSGTTGRPKG ++ H QTLR Y WCDLA LR GDRYLIVNPFFHTFGYKA Sbjct: 174 PDRPSDIVFTSGTTGRPKGAVITHEQTLRAYEVWCDLAGLRHGDRYLIVNPFFHTFGYKA 233 Query: 217 GCIASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATLR 274 G IA L+RGAT++P VFDVD ++ IA ERV++LPGPPTL+ SLL P D L+ LR Sbjct: 234 GVIACLMRGATMIPQPVFDVDTVLANIAAERVSVLPGPPTLHQSLLDHPARDAHDLSALR 293 Query: 275 AGVTGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACD 333 VTGAA +P+ L+ ++H EL ETV T YGL+EA G T+ R GD IA+T G A Sbjct: 294 LVVTGAAVVPLRLVEQLHGELGVETVLTAYGLSEASGIVTMCRQGDPLPVIASTSGRAIP 353 Query: 334 GVEVNL----ADDGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRI 389 G EV + + GEVLVRG++VM+GY +D AATAEA+ DGWL TGD+G SG LRI Sbjct: 354 GTEVRVQAPPGEPGEVLVRGFNVMRGYYEDAAATAEAVTEDGWLRTGDVGVLDASGNLRI 413 Query: 390 IGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGT 449 R KDMFIVGGFNAYPAEIE + HP VA VAV+GV D R+G+VG+A+VV R Sbjct: 414 TDRLKDMFIVGGFNAYPAEIEQLIGLHPAVADVAVVGVPDARLGEVGRAYVVRR-----P 468 Query: 450 RQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 +TA+DLIAW+R MA YKVPR VEF+ LP NA+GKV+K L+ Sbjct: 469 NTVLTADDLIAWARREMANYKVPRTVEFVATLPRNASGKVVKGELR 514 >tr|Q82GU0|Q82GU0_STRAW Tax_Id=33903 (fadD16)SubName: Full=Putative acyl-CoA synthetase, fatty acid:CoA ligase;[Streptomyces avermitilis] Length = 527 Score = 492 bits (1266), Expect = e-137 Identities = 279/535 (52%), Positives = 344/535 (64%), Gaps = 57/535 (10%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W +IP +V S+A+R+ D EAVV+ G R+++ EL RV RAA A +A G+G Sbjct: 7 WGSIPGLVRSSAERYADTEAVVE---------GRTRISYAELGARVERAAAACIASGVGV 57 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRV IWAPNS +W+++A GA++AG V+VP+NTRFK EAA V+RRSGA+++ FLG Sbjct: 58 GDRVGIWAPNSLDWIVSALGAVSAGAVLVPLNTRFKGSEAAYVLRRSGARLLFVTGTFLG 117 Query: 126 QDFEVPA---------------GVPAIE--------------IKSDFLASGEPAVVG--- 153 + G+PA+E DFLASGE Sbjct: 118 TSYVASLRRAAGEGEGLRGPLPGLPALEQVVVLADDAPADFRTWKDFLASGEGVGEAETR 177 Query: 154 ----GLRGTDIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFF 209 GL G+ ++DI++TSGTTGRPKG ++ H QTLR Y W DLA LR GDRYLI NPFF Sbjct: 178 ERARGLDGSTVSDIIFTSGTTGRPKGAVITHAQTLRAYEVWSDLAGLRRGDRYLIANPFF 237 Query: 210 HTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DK 267 HTFGYKAG IA L+RGAT++P VF+VD ++ IA ERV++LPGPPTL+ SLL P D Sbjct: 238 HTFGYKAGVIACLMRGATMIPQPVFNVDTVLANIAAERVSVLPGPPTLHQSLLDHPARDA 297 Query: 268 AKLATLRAGVTGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIAT 326 L+ LR VTGAA +P+ L+ R+ EL TV T YGL+EA G T+ R GD + IA+ Sbjct: 298 YDLSALRLVVTGAAVVPLRLVERLRGELGVGTVLTAYGLSEASGIVTMCRRGDDPSVIAS 357 Query: 327 TVGTACDGVEVN----LADDGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFT 382 T G A G EV L GEVLVRG++VM+GY +D ATA A+ DGWL TGD+G Sbjct: 358 TSGRAIPGTEVRVEAPLGSPGEVLVRGFNVMRGYFEDERATAAALTEDGWLRTGDVGVLD 417 Query: 383 ESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVL 442 SG LRI R KDMFIVGGFNAYPAEIE L HPDVA VAVIGV D R+G+VGKA+VV Sbjct: 418 ASGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVIGVPDARLGEVGKAYVVR 477 Query: 443 REPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 R +T +DLIAWSR MA YKVPR VEF+ ELP NA GKV+K L+ R Sbjct: 478 R-----PGSVLTGDDLIAWSRREMANYKVPRAVEFVGELPRNAGGKVVKGELRGR 527 >tr|B5HKL7|B5HKL7_STRPR Tax_Id=457429 SubName: Full=Acyl-CoA synthetase;[Streptomyces pristinaespiralis ATCC 25486] Length = 522 Score = 491 bits (1264), Expect = e-136 Identities = 272/525 (51%), Positives = 350/525 (66%), Gaps = 47/525 (8%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TI E+V +AA R+G EAVV+ G +R+ + EL +RV RAA A +A G+ +GD Sbjct: 11 TIGELVRTAALRYGQREAVVE---------GRIRVPYAELGERVERAAAACIASGVRKGD 61 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQ- 126 RVA+WAPN+ +W++ A GA+TAG V+VP+NTRFK EAA V+RRS A+++ FLG Sbjct: 62 RVAVWAPNTLDWIVCALGAVTAGAVLVPLNTRFKGTEAAYVLRRSRARLLFVTGTFLGTS 121 Query: 127 --------DFEVPAGVPAIEIKS----------DFLASGEPAVVGGLR-------GTDIA 161 D E+P + + DFLA G+ +R D + Sbjct: 122 YVASLRRCDVELPDLEQVVVLAESAPQEYRTWKDFLAGGDGVDARQVRERAATVTADDPS 181 Query: 162 DIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIAS 221 D+V+TSGTTGRPKG ++ H QTLR Y W +LA LREGDRYLIVNPFFHTFGYKAG +A Sbjct: 182 DLVFTSGTTGRPKGAVITHAQTLRCYDLWSELAGLREGDRYLIVNPFFHTFGYKAGVVAC 241 Query: 222 LIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTG 279 L RGAT++P VF+V+ ++ IA ER+++LPGPPTL+ SLL P + + L+TLR VTG Sbjct: 242 LTRGATMVPQPVFNVETVLANIAAERISVLPGPPTLHRSLLDHPARGRHDLSTLRLVVTG 301 Query: 280 AADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVN 338 AA +P++L+ R+ +EL TV T YGL+EA G T+ R GD+ +A T G A G EV Sbjct: 302 AAVVPLDLVERLRDELRVPTVLTAYGLSEASGIVTMCRRGDAPATVAATSGRAIPGTEVR 361 Query: 339 L----ADDGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKK 394 + + GEVLVRG++VM+GY +DPAATA AI DGWL TGD+G E G LRI R K Sbjct: 362 VLAPQGEPGEVLVRGHNVMRGYFEDPAATARAITPDGWLRTGDVGVLDEQGNLRITDRIK 421 Query: 395 DMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVT 454 DMFIVGGFNAYPAEIE L HPDVA VAVIGV D+R+G+VGKA+VV R +T Sbjct: 422 DMFIVGGFNAYPAEIEQLLGPHPDVADVAVIGVPDERLGEVGKAYVVRR-----PGSTLT 476 Query: 455 AEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAREA 499 A+DLIAWSR MA +KVPR+VEF+ LP NA+GKV+K L++R A Sbjct: 477 ADDLIAWSRREMANFKVPRHVEFVAALPRNASGKVLKTKLRSRHA 521 >tr|C9YV32|C9YV32_STRSW Tax_Id=680198 SubName: Full=Putative AMP-binding protein;[Streptomyces scabies] Length = 554 Score = 490 bits (1261), Expect = e-136 Identities = 284/554 (51%), Positives = 353/554 (63%), Gaps = 75/554 (13%) Query: 5 SWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIG 64 +W T+P +V SAA RFG EAVVD G R+T+ EL RV RAA A +A+G+ Sbjct: 15 AWGTVPGLVRSAARRFGGDEAVVD---------GRTRVTYAELGARVERAAAACVANGVR 65 Query: 65 RGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFL 124 GDRVA+WAPNS +W+++A GA++AG V+VP+NTRFK EAADV+ RS A+++ FL Sbjct: 66 TGDRVALWAPNSLDWIVSALGAVSAGAVLVPLNTRFKGGEAADVLARSRARLLFVTGTFL 125 Query: 125 GQDF------------------------EVPAGVPAI-----------------EIKSDF 143 G + E P +PA+ DF Sbjct: 126 GTSYVASLRRAAGADGGRLRARGAGSVCERPGPLPALPHLEQVVVLADDAPADFRTWKDF 185 Query: 144 LASG----EPAV---VGGLRGTDIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADL 196 LASG E AV L G +DIV+TSGTTGR KGV+++H QTLR Y W +LA L Sbjct: 186 LASGDGVGERAVRERAEALTGDSPSDIVFTSGTTGRSKGVVISHAQTLRAYEVWSELAGL 245 Query: 197 REGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPT 256 R GDRYLIVNPFFHTFGYKAG IA L+RGAT++P VF+V+ + +A ERVT+LPGPPT Sbjct: 246 RRGDRYLIVNPFFHTFGYKAGVIACLMRGATMIPQPVFNVETAMANVAAERVTVLPGPPT 305 Query: 257 LYHSLLGVP--DKAKLATLRAGVTGAADIPVELIRRIHEELPFETVATGYGLTEA-GTAT 313 L+ SLL P D L +LR VTGAA +P+ L+ R+ EL +TV T YGL+EA G T Sbjct: 306 LHQSLLDHPARDDYDLGSLRLVVTGAAVVPLRLVERLRAELRVDTVLTAYGLSEASGIVT 365 Query: 314 LSRPGDSFTDIATTVGTACDGVEVNLAD----------DGEVLVRGYSVMQGYLDDPAAT 363 + R GD + IA+T G A G EV + D GEVLVRG++VM+GY +DPA T Sbjct: 366 MCRRGDEPSVIASTSGRAIPGTEVRVVDPLGSALPAGSPGEVLVRGFNVMRGYFEDPAET 425 Query: 364 AEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVA 423 A A+ +DGWL TGD+G E+G LRI R KDMFIVGGFNAYPAEIE L HPDVA VA Sbjct: 426 ARAVTSDGWLRTGDVGVLDEAGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVA 485 Query: 424 VIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPL 483 V+GV D R+G+VG+A+VV R G+ VTA+DLIAWSR MA YKVPR VEF+ ELP Sbjct: 486 VVGVPDTRLGEVGRAYVVRR---PGSH--VTADDLIAWSRREMANYKVPRSVEFMRELPR 540 Query: 484 NATGKVMKDHLKAR 497 NA+GKV+K L+ R Sbjct: 541 NASGKVVKGELRGR 554 >tr|B1W549|B1W549_STRGG Tax_Id=455632 SubName: Full=Putative fatty acid:CoA ligase;[Streptomyces griseus subsp. griseus] Length = 518 Score = 485 bits (1248), Expect = e-135 Identities = 270/525 (51%), Positives = 339/525 (64%), Gaps = 47/525 (8%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W +IPE+V +AA R+G AEAV D G RL++ EL +RV RAA A LA G+ Sbjct: 7 WGSIPELVRAAARRYGSAEAVAD---------GRTRLSYAELGERVERAAAACLASGVEP 57 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVAIWAPN+ +W+I+A GA+TAG V+VP+NTRFK EAA V+RRS A+++ FLG Sbjct: 58 GDRVAIWAPNTPDWIISALGAVTAGAVLVPLNTRFKGTEAAYVLRRSRARLLFVTGTFLG 117 Query: 126 QDFEVPAGVPAIEIKS-------------------DFLASGEPAVVGGLRG-------TD 159 + + + DFLA+GE + +R +D Sbjct: 118 TSYVASLRRAEVRLPDLERVVVLADTAPEDYTSWPDFLAAGEGVLPSAVRERAAAIAPSD 177 Query: 160 IADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCI 219 +DI+YTSGTTG PKG ++ H QTLR Y W DLA LREGDRYLIVNPFFHTFGYKAG I Sbjct: 178 PSDIIYTSGTTGAPKGAVITHAQTLRAYGIWSDLAGLREGDRYLIVNPFFHTFGYKAGII 237 Query: 220 ASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATLRAGV 277 A L+RGAT++P VF+VD ++ IA ER+++LPGPPTL+ SLL P D L+ LR V Sbjct: 238 ACLMRGATMVPQPVFNVDTVLANIAAERISVLPGPPTLHQSLLDHPARDAHDLSALRLVV 297 Query: 278 TGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVE 336 TGAA +P+ L+ R+ EL TV T YGL+EA G T+ R GD+ +ATT G A G E Sbjct: 298 TGAAVVPLRLVERLRNELRIATVLTAYGLSEASGIVTMCRRGDAPEVVATTSGRAIPGTE 357 Query: 337 VNLADD----GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGR 392 + + + GEV VRG+ VM GY +DP TA + DGWL TGD+G +G LRI R Sbjct: 358 LRVLAEPGAPGEVQVRGFHVMGGYFEDPDTTAATMTEDGWLRTGDVGVLDAAGNLRITDR 417 Query: 393 KKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQC 452 KDMFIVGGFNAYPAEIE L HPDVA VAV+G+ D R+G+VGKA+ V R Sbjct: 418 IKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVVGIPDPRLGEVGKAYAVRRR-----GAT 472 Query: 453 VTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 +TA+DLIAWSR MA +KVPR VEF+ ELP NA+GKV+K L+ R Sbjct: 473 LTADDLIAWSRREMANFKVPRAVEFVAELPRNASGKVVKGELRGR 517 >tr|D1XB68|D1XB68_9ACTO Tax_Id=649189 SubName: Full=AMP-dependent synthetase and ligase;[Streptomyces sp. ACT-1] Length = 519 Score = 485 bits (1248), Expect = e-135 Identities = 269/525 (51%), Positives = 339/525 (64%), Gaps = 47/525 (8%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W +IPE+V +AA R+G AEAV D G RL++ EL +RV RAA A LA G+ Sbjct: 8 WGSIPELVRAAARRYGSAEAVAD---------GRTRLSYTELGERVERAAAACLASGVEP 58 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVAIWAPN+ +W+++A GA+TAG V+VP+NTRFK EAA V+RRS A+++ FLG Sbjct: 59 GDRVAIWAPNTPDWIVSALGAVTAGAVLVPLNTRFKGTEAAYVLRRSRARLLFVTGTFLG 118 Query: 126 QDFEVPAGVPAIEIKS-------------------DFLASGEPAVVGGLRG-------TD 159 + + + DFLA+GE + +R +D Sbjct: 119 TSYVASLRRAEVRLPDLERVVVLADTAPEDYTSWPDFLAAGEGVLPSAVRERAAAIAPSD 178 Query: 160 IADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCI 219 +DI+YTSGTTG PKG ++ H QTLR Y W DLA LREGDRYLIVNPFFHTFGYKAG I Sbjct: 179 PSDIIYTSGTTGAPKGAVITHAQTLRAYGIWSDLAGLREGDRYLIVNPFFHTFGYKAGII 238 Query: 220 ASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATLRAGV 277 A L+RGAT++P VF+VD ++ IA ER+++LPGPPTL+ SLL P D L+ LR V Sbjct: 239 ACLMRGATMVPQPVFNVDTVLANIAAERISVLPGPPTLHQSLLDHPARDAHDLSALRLVV 298 Query: 278 TGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVE 336 TGAA +P+ L+ R+ EL TV T YGL+EA G T+ R GD+ +ATT G A G E Sbjct: 299 TGAAVVPLRLVERLRNELRIATVLTAYGLSEASGIVTMCRRGDAPEVVATTSGRAIPGTE 358 Query: 337 VNLADD----GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGR 392 + + + GEV VRG+ VM GY +DP TA + DGWL TGD+G +G LRI R Sbjct: 359 LRILAEPGAPGEVQVRGFHVMGGYFEDPDTTAATMTEDGWLRTGDVGVLDAAGNLRITDR 418 Query: 393 KKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQC 452 KDMFIVGGFNAYPAEIE L HPDVA VAV+G+ D R+G+VGKA+ V R Sbjct: 419 IKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVVGIPDPRLGEVGKAYAVRRR-----GAT 473 Query: 453 VTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 +TA+DLIAWSR MA +KVPR VEF+ ELP NA+GKV+K L+ R Sbjct: 474 LTADDLIAWSRREMANFKVPRAVEFVAELPRNASGKVVKGELRGR 518 >tr|D6ADT8|D6ADT8_STRFL Tax_Id=457431 SubName: Full=Acyl-CoA synthetase;[Streptomyces roseosporus NRRL 15998] Length = 519 Score = 478 bits (1229), Expect = e-132 Identities = 268/525 (51%), Positives = 336/525 (64%), Gaps = 51/525 (9%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W +IP ++ +AA R+G AEAV D G RLT+ EL +V RAA A + G+ Sbjct: 8 WGSIPGLIRAAARRYGPAEAVAD---------GRTRLTYAELGAQVERAAAACMGAGVEP 58 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVAIWAPN+ EW+++A GA++AG V+VP+NTRFK EAA ++RRS A+++ FLG Sbjct: 59 GDRVAIWAPNTTEWIVSALGAVSAGAVLVPLNTRFKGTEAAHILRRSRARLLFVTGTFLG 118 Query: 126 QDFEVPAGVPAIEIK---------------------SDFLASGEPAVVGGLRGTDIA--- 161 + A + E+K DFLA+GE +R A Sbjct: 119 TSYV--ASLRRAEVKLPDLERVVVLADTAPEDYTSWPDFLAAGEGVESSAVRDRAAAIAP 176 Query: 162 ----DIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAG 217 DI+YTSGTTG PKG ++ H QTLR Y W DLA LREGDRYLIVNPFFHTFGYKAG Sbjct: 177 SSPSDIIYTSGTTGAPKGAVITHAQTLRAYEIWSDLAGLREGDRYLIVNPFFHTFGYKAG 236 Query: 218 CIASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATLRA 275 IA L+RGAT++P VF+VD ++ IA ER+++LPGPPTL+ SLL P D L LR Sbjct: 237 IIACLMRGATMVPQPVFNVDTVLANIAAERISVLPGPPTLHQSLLDHPARDAHDLTALRL 296 Query: 276 GVTGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDG 334 VTGAA +P++L+ R+ EL TV T YGL+EA G T+ R GD+ +ATT G A G Sbjct: 297 VVTGAAVVPLQLVERLRNELGIATVLTAYGLSEASGIVTMCRRGDAPEIVATTSGRAIPG 356 Query: 335 VEVNLADD----GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRII 390 E+ + D GE+ VRG++VM GY +DP TA + DGWL TGD+G +G LRI Sbjct: 357 TEIRVLADPGAPGEIQVRGFTVMTGYFEDPDTTAATMTEDGWLRTGDVGVLDPAGNLRIT 416 Query: 391 GRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTR 450 R KDMFIVGGFNAYPAEIE L HPDVA VAVIGV D R+G+VGKA+ V R Sbjct: 417 DRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVIGVPDPRLGEVGKAYAVRRR-----G 471 Query: 451 QCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 +TA+DLIAWSR MA +KVPR VEF+ ELP NA+GKV+K L+ Sbjct: 472 ATLTADDLIAWSRREMANFKVPRTVEFVPELPRNASGKVVKGELR 516 >tr|B5GNI3|B5GNI3_STRCL Tax_Id=443255 SubName: Full=Acyl-CoA synthetase;[Streptomyces clavuligerus ATCC 27064] Length = 601 Score = 471 bits (1213), Expect = e-131 Identities = 266/529 (50%), Positives = 334/529 (63%), Gaps = 51/529 (9%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W T+ +V AA+R+ D EAVVD G R+T+ EL RV RAA A +A GI R Sbjct: 64 WGTVGRLVRDAAERYADHEAVVD---------GRTRVTYAELGTRVERAAAACIAAGIRR 114 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVA+WAPN+ +W++ A GA+TAG V+VP+NTRFK EAADV+ RS A+++ FLG Sbjct: 115 GDRVALWAPNTLDWIVCALGAVTAGAVLVPLNTRFKGPEAADVLARSRARLLFVTGAFLG 174 Query: 126 QDF-------EVPAGVPAIE--IKSDFLASGEP--------AVVGGLRGT---------- 158 + AG+P +E + + A +P GG G Sbjct: 175 TSYVAALRRETAGAGLPHLERVVVLEGPAPADPRYRTWDAFRADGGTIGADEVRARADSV 234 Query: 159 ---DIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYK 215 D +DIVYTSGTTGRPKG ++ H QTLR Y W +LA LR DRYLIVNPFFHTFGYK Sbjct: 235 GPGDTSDIVYTSGTTGRPKGAVLTHAQTLRCYDLWSELAGLRGDDRYLIVNPFFHTFGYK 294 Query: 216 AGCIASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATL 273 AG IA L RGAT++P VFD ++ IA ERVT+LPGPPTL+ +LL P D L+TL Sbjct: 295 AGIIACLTRGATMIPQPVFDTATVLARIAAERVTVLPGPPTLHQTLLDHPARDHHDLSTL 354 Query: 274 RAGVTGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTAC 332 R VTGAA +P+ L+ R+ EL +TV T YGL+EA G T+ R D +A T G A Sbjct: 355 RLVVTGAAVVPLSLVERLRSELRIDTVLTAYGLSEAGGLVTMCRRDDPPGAVAATSGHAV 414 Query: 333 DGVEVNLAD----DGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLR 388 G E+ + GE+LVRG V +GY +DP ATA A+DADGWLHTGD+G +GRL Sbjct: 415 PGTELRILAGPGLPGEILVRGPQVTRGYFEDPGATAAAVDADGWLHTGDIGVLDPAGRLT 474 Query: 389 IIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDG 448 + R DM++VGGFNAYPAEIE L HPD+A VAV+GV D R+G+VG+A+ V R Sbjct: 475 VTDRVTDMYVVGGFNAYPAEIERLLGLHPDIADVAVVGVPDRRLGEVGRAYAVRR----- 529 Query: 449 TRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 +TA+DLIAW+R MA YKVPR V F+ ELP NA GKV+K L+AR Sbjct: 530 PGATLTADDLIAWARREMANYKVPREVSFVAELPRNAGGKVLKAELRAR 578 >tr|B4V6W7|B4V6W7_9ACTO Tax_Id=465541 SubName: Full=Acyl-CoA synthetase;[Streptomyces sp. Mg1] Length = 532 Score = 471 bits (1211), Expect = e-130 Identities = 269/540 (49%), Positives = 335/540 (62%), Gaps = 62/540 (11%) Query: 6 WQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGR 65 W ++ E+V AA+R+ + +AVVD G +R+ + +L +RV RAA A +A G+ Sbjct: 7 WGSVAELVRDAAERYAERDAVVD---------GRVRIDYAQLGERVERAAAACIAAGVEA 57 Query: 66 GDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLG 125 GDRVA+WAPN+ EW+++A GA++AG V+VP+NTRFK EAA V+RRS A+++ FLG Sbjct: 58 GDRVAVWAPNTLEWIVSALGAVSAGAVLVPLNTRFKGAEAAYVLRRSRARLLFVTGTFLG 117 Query: 126 QDF---------EVPAGVPAIEIK-------------------SDFLASGEPAVVGGLRG 157 + E P P ++ DFLA G+ +R Sbjct: 118 TSYVASLRRAAAEGPGTGPLPGLEHLEQVVVLAEDAPASFRTWKDFLAGGDRVPAEAVRA 177 Query: 158 TDIA-------DIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFH 210 A DI++TSGTTG PKG ++ H QTLR Y W +LA LREGDRYLIVNPFFH Sbjct: 178 RAAAIRPDAPSDIIFTSGTTGSPKGAVITHAQTLRCYDVWSELAGLREGDRYLIVNPFFH 237 Query: 211 TFGYKAGCIASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLL--GVPDKA 268 TFGYKAG IA L RGAT++P VFDVD ++ +A ER+++LPGPPTL+ SLL D Sbjct: 238 TFGYKAGIIACLTRGATMVPQPVFDVDTVLANVAAERISVLPGPPTLHQSLLDHAHRDHH 297 Query: 269 KLATLRAGVTGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATT 327 L+ LR VTGAA IP+ L+ R+ EL TV T YGL+EA G T+ R GD IA T Sbjct: 298 DLSALRLVVTGAAVIPLRLVERLRGELRIATVLTAYGLSEASGIVTMCRRGDPAEVIAQT 357 Query: 328 VGTACDGVEVNLADD----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGD 377 G G EV +AD GEV VRG+ VM+GY +DPA TA AI DGWL TGD Sbjct: 358 SGRPVPGTEVRIADPEGAPLPAGRAGEVWVRGHHVMRGYFEDPAETARAITPDGWLRTGD 417 Query: 378 LGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGK 437 +G G LRI R KDMFIVGGFNAYPAEIE L HPD+A VAV+GV D R+G+VGK Sbjct: 418 VGVLDADGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDIADVAVVGVPDPRLGEVGK 477 Query: 438 AFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 A+ V R VTA+DLIAWSR MA YKVPR VEF+ ELP NA GKV+K L+AR Sbjct: 478 AYAVRR-----PGATVTADDLIAWSRREMANYKVPREVEFVGELPRNAGGKVLKRELRAR 532 >tr|D1VMU0|D1VMU0_9ACTO Tax_Id=298654 SubName: Full=AMP-dependent synthetase and ligase;[Frankia sp. EuI1c] Length = 542 Score = 466 bits (1198), Expect = e-129 Identities = 260/533 (48%), Positives = 340/533 (63%), Gaps = 50/533 (9%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TIP ++ AA R+ EA+VD G RLTF +LA AA A +A G+ GD Sbjct: 21 TIPAVLDRAARRWPADEALVD---------GATRLTFAQLAAAADEAARALVASGVEPGD 71 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RV+IWAPN WM+AA G AG +VPVN+RFKA EAA ++R +GAK++ FL D Sbjct: 72 RVSIWAPNGHRWMVAALGIYRAGATLVPVNSRFKAGEAAGLLRATGAKILFTVTDFLATD 131 Query: 128 F--------EVPA----------GVPAIEIKSDFL--ASGEPAVV-----GGLRGTDIAD 162 + ++PA PA +DF+ A+ PA V L G D++D Sbjct: 132 YAAAIHAEPDLPALGEVVVLDGPASPATTQWADFVTRAATVPAEVTAARAAALTGDDVSD 191 Query: 163 IVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASL 222 I++TSGTTG+PKG M+ H + RLY W D+ L GDRYL+V PFFHT G KAG +ASL Sbjct: 192 IIFTSGTTGKPKGAMLAHGPSTRLYTSWADVIGLGHGDRYLLVYPFFHTAGLKAGLLASL 251 Query: 223 IRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKA-KLATLRAGVTGAA 281 + GAT++P VFDV A++ L+ TE++TMLPGPP +Y ++L L++ R VTG+A Sbjct: 252 LVGATLVPYPVFDVPAVMRLVETEKITMLPGPPAVYQTILNSDLTGYDLSSWRLAVTGSA 311 Query: 282 DIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVNLA 340 +PVEL+RR+ +L TV TGYGLTE GT + R D ++ T G A DG+EV + Sbjct: 312 AVPVELVRRLRADLGLRTVVTGYGLTETTGTVAMCRHTDDPELVSRTSGRALDGIEVRVV 371 Query: 341 DD----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRII 390 DD GE++VRG+++M GYLD+PAATAE IDADGWL TGD+G + G + I Sbjct: 372 DDAGTEVPRGEPGEIIVRGFNIMTGYLDNPAATAETIDADGWLKTGDIGVMDDGGNIAIT 431 Query: 391 GRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTR 450 RKKDMFIVGGFNAYPAEIE L EHP +AQVAV+GV D+R+G+VG A+V+ P G Sbjct: 432 DRKKDMFIVGGFNAYPAEIESMLAEHPAIAQVAVVGVPDERLGEVGMAYVI---PRTGQP 488 Query: 451 QCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAREALSKR 503 + AE +IAWSR+RMA YK PRYVE ++ LPLNATGKV++ L+ R A + R Sbjct: 489 RPTPAE-IIAWSRDRMANYKAPRYVEVVDALPLNATGKVVRYELRDRAAATLR 540 >tr|D3DB50|D3DB50_9ACTO Tax_Id=102897 SubName: Full=AMP-dependent synthetase and ligase;[Frankia sp. EUN1f] Length = 597 Score = 463 bits (1191), Expect = e-128 Identities = 262/529 (49%), Positives = 333/529 (62%), Gaps = 54/529 (10%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TIP + AA R+ EA+VD G RLTF +L R A A +A G+ GD Sbjct: 66 TIPAALARAAARWPHDEAIVD---------GDQRLTFADLDARTAEVARALVASGVRAGD 116 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RV++WAPN+ EW + A G AG V+ P+N+RFK EAA ++R +G++++ GFL D Sbjct: 117 RVSVWAPNTCEWALVALGVYRAGAVLAPINSRFKGVEAARILRTAGSRLLFVVDGFLDTD 176 Query: 128 F-----EVPAGVPAIEIK--------------SDFLA--SGEP-----AVVGGLRGTDIA 161 + E PA +I DFLA G+P A L G D++ Sbjct: 177 YLTMLAEQPAPPALADIVLMGSATGRAGATGWPDFLARAEGQPDAEVAARSAALTGDDLS 236 Query: 162 DIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIAS 221 DIV+TSGTTG PKG M+ H + +Y W L LR GDRYL+V PFFHT G K+G +A Sbjct: 237 DIVFTSGTTGAPKGAMLTHGASTGVYTSWSQLVGLRHGDRYLLVYPFFHTAGLKSGLLAC 296 Query: 222 LIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKA--KLATLRAGVTG 279 L+ GAT++P VFDV +++ +A ER+TMLPGPP +Y S+L D A L++LR VTG Sbjct: 297 LLVGATLVPHPVFDVPSVLRRVAQERITMLPGPPAIYQSILNT-DLAGYDLSSLRLAVTG 355 Query: 280 AADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVN 338 AA +PVEL+RR+ EL +TV T YGLTE GTAT R D IA T G A GVEV Sbjct: 356 AAAVPVELVRRLRSELGLQTVLTAYGLTETTGTATACRRDDDPETIAMTSGRAIPGVEVR 415 Query: 339 LADD----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLR 388 + DD GE+++RGY+VM+GY D+P ATAEAIDADGWLH+GD+G E+G +R Sbjct: 416 IVDDTGAPLPPGEPGEIVIRGYNVMRGYFDNPDATAEAIDADGWLHSGDIGVQDEAGNIR 475 Query: 389 IIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDG 448 I RKKDMFIVGGFNAYPAEIE LLEH +AQVAVIGV D+R+G+VG AFV+ R + Sbjct: 476 ITDRKKDMFIVGGFNAYPAEIEAMLLEHGGIAQVAVIGVPDERLGEVGMAFVIPRAGV-- 533 Query: 449 TRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 V +IAWSRERMA YKVPR VE ++ LPLNATGK++K L+ R Sbjct: 534 ---TVDPAQVIAWSRERMANYKVPRRVEVVDALPLNATGKIVKYELRDR 579 >tr|C7Q240|C7Q240_CATAD Tax_Id=479433 SubName: Full=AMP-dependent synthetase and ligase;[Catenulispora acidiphila] Length = 510 Score = 452 bits (1164), Expect = e-125 Identities = 258/518 (49%), Positives = 328/518 (63%), Gaps = 44/518 (8%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TIP++V AA GD EAVVD G RLTF ELA RVR+A A +A G+ GD Sbjct: 7 TIPDLVARAAAEHGDQEAVVD---------GEQRLTFAELAARVRQAGRAMIAWGVRPGD 57 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RVAIWAPNSAEW+ A GA++ G V+VP+NTR KA E ++R S ++V FLG D Sbjct: 58 RVAIWAPNSAEWIATALGAVSVGAVLVPLNTRLKAAEVGYILRTSRTRLVAVAGEFLGVD 117 Query: 128 F---------EVP----------AGVPAIEIKSDFLASGE--PAVV-----GGLRGTDIA 161 + E+P G+P + + F A G PA V L A Sbjct: 118 YVGQLAAIHDELPDLETLTAFTDGGLPPVVSRRQFRAPGMKVPAPVFDEAAASLTPDSPA 177 Query: 162 DIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIAS 221 D+ +TSGTTG PKGV H QT R + W ++ LR GDRYLI NPF HTFGYKAG +A Sbjct: 178 DLFFTSGTTGAPKGVETTHGQTTRAFHAWSEIVGLRAGDRYLIANPFSHTFGYKAGILAC 237 Query: 222 LIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTG 279 L+RGAT++P+ FD +A+ I ER+T+ P P +Y +L PD AK L++LRA TG Sbjct: 238 LMRGATMVPLPSFDAEALFTTIEQERITVFPAAPAVYQMMLAHPDLAKHDLSSLRAAATG 297 Query: 280 AADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVN 338 AA IPVELI R+ + L TV T YGLTEA G T+ R GD+ +A T G A +GVEV Sbjct: 298 AAVIPVELIERMRDTLGLSTVITAYGLTEATGVVTMCRDGDTPDVVARTSGRAIEGVEVR 357 Query: 339 LAD-DGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMF 397 +A+ GE+LVRGY+VM GY +D AATAEAIDADGWLHTGD+G+ E+G LRI R KDM+ Sbjct: 358 IAEATGEILVRGYNVMSGYFEDEAATAEAIDADGWLHTGDVGDLDEAGNLRITDRIKDMY 417 Query: 398 IVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAED 457 I GGFNAYPAEIE LL P V + AVIGV D R+G+VGKAFV+ + G R + + Sbjct: 418 ICGGFNAYPAEIEQVLLTFPGVQEAAVIGVPDQRLGEVGKAFVI---AVPGQR--IEPAE 472 Query: 458 LIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 L+ ++ ER+A YKVPR++E +E P ++ GKV+K L+ Sbjct: 473 LLKYAEERLANYKVPRHLELVEAFPRSSLGKVLKRELQ 510 >tr|A1SKD5|A1SKD5_NOCSJ Tax_Id=196162 SubName: Full=AMP-dependent synthetase and ligase;[Nocardioides sp.] Length = 489 Score = 450 bits (1158), Expect = e-124 Identities = 239/502 (47%), Positives = 318/502 (63%), Gaps = 32/502 (6%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TIP ++ +AA+RFGD +PA G + +F +L RVRR A + A G+ GD Sbjct: 4 TIPGVLRAAAERFGD---------HPAYVEGGVTTSFTDLLGRVRRTAAGYRARGLSPGD 54 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQ- 126 RV +WAPNS +W++AA AGG +VP N+R+ E AD++ R+GA +V+ GFLG+ Sbjct: 55 RVVVWAPNSVDWVVAALAVSYAGGTLVPANSRYTGHEVADLVDRTGAVLVVVADGFLGRT 114 Query: 127 ---DFEVPAGVPAIEIKSDFL----ASGEPAVVGGLRGT----DIADIVYTSGTTGRPKG 175 D +P + D EP V+ + D+ADI++TSGTTGRPKG Sbjct: 115 QVADLRAAGALPGVREVIDLARIAEVEAEPGVIDEVAAAVSPDDVADILFTSGTTGRPKG 174 Query: 176 VMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFD 235 M H QT+ + W L + DRYL+VNPFFH+FGYK G + LI GAT+ P+A FD Sbjct: 175 AMSAHRQTVGVARAWGSLGGVSTEDRYLVVNPFFHSFGYKVGIVTGLITGATLYPLATFD 234 Query: 236 VDAIVELIATERVTMLPGPPTLYHSLLGVPDKA--KLATLRAGVTGAADIPVELIRRIHE 293 +D + LI TER+T+LPG PT+Y SLL P +A L++LR VTGAA +PV LI R+ E Sbjct: 235 LDETMRLIETERITVLPGAPTIYQSLLSAPGRAGRDLSSLRLAVTGAAVVPVVLIERMRE 294 Query: 294 ELPFETVATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLADDGEVLVRGYSVM 353 EL + V T +G+TEA T+ R GDS +ATT G A G+E + GE+LVRG VM Sbjct: 295 ELGIDHVVTAFGMTEAVVVTMCRDGDSAETVATTCGRAIPGMETRIGARGELLVRGEFVM 354 Query: 354 QGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFNAYPAEIEGFL 413 GYLDDPAATAEAIDA+GWLHTGD+G E G L I R KDM+I GGFN YPAE+E L Sbjct: 355 LGYLDDPAATAEAIDAEGWLHTGDVGVLDEHGNLSITDRLKDMYICGGFNVYPAEVEQAL 414 Query: 414 LEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSRERMAGYKVPR 473 VA VAV+GV D+R+G+VGKA+VV VT ++++A+++ER+A +KVPR Sbjct: 415 ARMDGVADVAVVGVPDERLGEVGKAYVV---------GAVTPDEVLAFAKERLANFKVPR 465 Query: 474 YVEFLEELPLNATGKVMKDHLK 495 VE + LP N +GKV+K+ L+ Sbjct: 466 SVEVTDALPRNLSGKVLKNELR 487 >tr|Q0K3I3|Q0K3I3_RALEH Tax_Id=381666 SubName: Full=Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; EC=6.2.1.-;[Ralstonia eutropha] Length = 546 Score = 449 bits (1155), Expect = e-124 Identities = 260/529 (49%), Positives = 330/529 (62%), Gaps = 55/529 (10%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TIPE+V AA R G+ A+ + G LRLT+ L +AA A +A G+ GD Sbjct: 30 TIPELVRRAARRHGERIAIQEDG---------LRLTYAALDASRIQAARALMALGVQPGD 80 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RVAIWAPN +EW+IAA + G +VP+NTR K EA V+ SGA+++L FLG+ Sbjct: 81 RVAIWAPNFSEWIIAALATHSIGAALVPLNTRMKGAEAGAVLADSGARLLLCVDAFLGES 140 Query: 128 FEV------PAGVPAIEIKSD---------------FLASGEPAVVG-------GLRGTD 159 + PA + + I FLA A + G+RG Sbjct: 141 YPQMLAPHRPATLERLVILRPGQGRTPGPDELAWEAFLALAPQADMAAFAKREDGVRGDT 200 Query: 160 IADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCI 219 + DI++TSGTTGRPKGVM H Q LR W + +R GDRYLIVNPFFHTFGYKAG + Sbjct: 201 LMDIMFTSGTTGRPKGVMTAHAQNLRAVDGWAAITGVRPGDRYLIVNPFFHTFGYKAGWL 260 Query: 220 ASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATLRAGV 277 A+L RGATVLP VFD +A++ + ER+T+LPGPPTLY +LL P + L++LR V Sbjct: 261 AALSRGATVLPHLVFDAEAVMTRVENERITVLPGPPTLYQTLLNAPRLREFDLSSLRVAV 320 Query: 278 TGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVE 336 TGA+ I LI+R+ +EL F+T+ TGYGLTE+ G ATL+R GD +A T G A G+E Sbjct: 321 TGASAIAPALIQRMRDELGFDTIITGYGLTESCGFATLTRAGDDAETVAATSGRAMPGIE 380 Query: 337 VNLADD----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGR 386 + D GEVLVRGY+VMQGY P ATAEAID++GWLHTGD+G G Sbjct: 381 IRCIDGQGQPAATGEAGEVLVRGYNVMQGYFGLPEATAEAIDSEGWLHTGDVGTLDARGY 440 Query: 387 LRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPL 446 LRI R KDMFIVGGFN YPAE+E L+ HP VAQVAV+G+ +R+G+VG+A+VVLR Sbjct: 441 LRITDRIKDMFIVGGFNCYPAEVEKLLVAHPAVAQVAVVGIPHERLGEVGRAYVVLRH-- 498 Query: 447 DGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 G R V AE LIAW+R MA YKVPR V F+ LP++A GKV+K L+ Sbjct: 499 -GAR--VDAEALIAWARRHMANYKVPREVLFVTSLPVSAAGKVLKYQLR 544 >tr|D1AB70|D1AB70_THECD Tax_Id=471852 SubName: Full=AMP-dependent synthetase and ligase;[Thermomonospora curvata] Length = 524 Score = 445 bits (1144), Expect = e-123 Identities = 258/525 (49%), Positives = 324/525 (61%), Gaps = 54/525 (10%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TIP ++ A F DAEAVVD +R+TF EL +RVR AA AF+ GIGRGD Sbjct: 11 TIPAVLDRAVRDFPDAEAVVDR---------QVRVTFSELGERVRAAARAFVGSGIGRGD 61 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 R+AIWAPNS W++AA GA+ AG V+VP+NTR+K EEA + ++ KV+ + FLG D Sbjct: 62 RIAIWAPNSLSWIVAALGAVCAGAVLVPLNTRYKGEEARWPLTKAKVKVLFVEDDFLGID 121 Query: 128 FE---------VPAGVPAIEIKSDFLASGEPAVVGGLRGT---------------DIADI 163 + G+P ++ F P V+ R D+ADI Sbjct: 122 YPGMLGLEESGTLPGLPDLQTVVTFNGPERPGVISWERWLARGEGASDPDPVAPGDVADI 181 Query: 164 VYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLI 223 ++TSGTTGRPKGV+ H Q +R Y W + GDRYLI+NPFFHTFGYKAG +A L+ Sbjct: 182 LFTSGTTGRPKGVLSTHEQNVRTYLAWSGRTGVTAGDRYLIINPFFHTFGYKAGVLACLL 241 Query: 224 RGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATLRAGVTGAA 281 RGAT++ VFDV + LI TE++T+LPGPPT+Y SLL P D+ L++LR VTGAA Sbjct: 242 RGATMVLQRVFDVPETLHLIETEKITVLPGPPTIYTSLLDAPDLDERDLSSLRLAVTGAA 301 Query: 282 DIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVNLA 340 D+PV L+RRI P V T YGLTE+ GT T D +ATT G + VEV +A Sbjct: 302 DVPVALVRRIRTLFP--QVITAYGLTESTGTVTACSVDDDDVTVATTSGRPIEDVEVMIA 359 Query: 341 ----------DDGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRII 390 DGE+LVRGY+VM GYLDDP ATAEA+ DGWL TGD G+ E G L I Sbjct: 360 GPDWRPLPPGQDGEILVRGYNVMSGYLDDPEATAEAL-RDGWLVTGDRGKLDERGYLTIT 418 Query: 391 GRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTR 450 GR KDMF VGGFN YPAEIE L+ H VA+ AVIGV D R+G+VG+A+V LR G R Sbjct: 419 GRSKDMFTVGGFNVYPAEIESVLVRHEAVAEAAVIGVPDQRLGEVGRAYVRLR---PGRR 475 Query: 451 QCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 TAE+LIA R+ +A +KVPR V F+++ P A GKV K L+ Sbjct: 476 --ATAEELIAHCRDALANFKVPREVVFVDDFPRTAAGKVRKVDLR 518 >tr|B2AIT8|B2AIT8_CUPTR Tax_Id=164546 SubName: Full=Putative fatty-acid--CoA ligase; EC=6.2.1.-;[Cupriavidus taiwanensis] Length = 543 Score = 444 bits (1142), Expect = e-122 Identities = 255/531 (48%), Positives = 328/531 (61%), Gaps = 55/531 (10%) Query: 7 QTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRG 66 +TIPE++ AA R G+ A+ + G LRLT+ L +A A +A G+ G Sbjct: 26 ETIPELLRRAASRHGERIAIQEDG---------LRLTYAALDAGRIQAGRALMALGVQPG 76 Query: 67 DRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQ 126 DRVA+WAPN +EW+IAA + G +VP+NTR K EA V+ SGA+++ GFLG+ Sbjct: 77 DRVAVWAPNFSEWIIAALATHSVGAALVPLNTRMKGAEAGAVLADSGARLLFCVDGFLGE 136 Query: 127 DF------EVPAGVPAIEIK---------------SDFLA-------SGEPAVVGGLRGT 158 + P + + I DF+A + A G+RG Sbjct: 137 SYPRMLAPHRPGTLERLVILRPGQGRAAGADELTWEDFIALAPRTDIAAFAAREAGVRGD 196 Query: 159 DIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGC 218 DI++TSGTTGRPKGVM H Q LR W + +R GDRYLIVNPFFHTFGYKAG Sbjct: 197 TPMDIMFTSGTTGRPKGVMTAHAQNLRAIDSWAAITGVRAGDRYLIVNPFFHTFGYKAGW 256 Query: 219 IASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATLRAG 276 +A+L RGATVLP VFD +A++ + E +T+LPGPPTLY +LL P + L++LR Sbjct: 257 LAALSRGATVLPHLVFDAEAVMTRVENEGITVLPGPPTLYQTLLNAPRLREFDLSSLRVA 316 Query: 277 VTGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGV 335 VTGA+ I LI+R+ +EL F+T+ TGYGLTE+ G ATL+R GD +A T G A G+ Sbjct: 317 VTGASAIAPALIQRMRDELGFDTIITGYGLTESCGFATLTRAGDDAETVAGTSGRAMPGI 376 Query: 336 EVNLAD----------DGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESG 385 E+ D GEVLVRGY+VMQGY P ATAE ID+DGWLHTGD+G G Sbjct: 377 EIRCIDAHGETVATGEPGEVLVRGYNVMQGYFGLPEATAETIDSDGWLHTGDVGTLDARG 436 Query: 386 RLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREP 445 LRI R KDMFIVGGFN YPAE+E L+ HP VAQVAV+G+ +R+G+VG+A+VVLR Sbjct: 437 YLRITDRIKDMFIVGGFNCYPAEVEKLLVAHPAVAQVAVVGMPHERLGEVGRAYVVLRH- 495 Query: 446 LDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKA 496 G R V A+ LIAW+R MA YKVPR V F+ LP++A GKV+K L+A Sbjct: 496 --GAR--VDADTLIAWARRHMANYKVPREVLFVSSLPVSAAGKVLKYQLRA 542 >tr|A5VBI6|A5VBI6_SPHWW Tax_Id=392499 SubName: Full=AMP-dependent synthetase and ligase;[Sphingomonas wittichii] Length = 511 Score = 441 bits (1135), Expect = e-122 Identities = 251/525 (47%), Positives = 325/525 (61%), Gaps = 44/525 (8%) Query: 1 MTHPSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLA 60 M P+ T+ ++ AA R+GD V + AG R R +GA LA Sbjct: 1 MVLPTTLTMGVLLDEAAGRWGDRPFVREEDGGVLSFAGFRRAA--------RAVSGALLA 52 Query: 61 HGIGRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQ 120 G +GDR+AIWAPNS W +AA GA G ++P+NTRFK EA D++RR + + Sbjct: 53 RGARKGDRIAIWAPNSGAWAVAAAGATQIGLELIPLNTRFKGAEAEDILRRGEVRWLFTV 112 Query: 121 QGFLGQDFEVPA---GVPAIEIKSDFL-----------ASGEP---AVVGGLRGTDIADI 163 +GFLG D+ +P +E ++ FL +G+ A + + G D DI Sbjct: 113 RGFLGLDYAAMLEGRDLPRLE-ETVFLDGLDAWLAAKGGAGDAEVSAAIAAVGGDDTVDI 171 Query: 164 VYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLI 223 ++TSGTTGRPKGVM H Q LR + W D LREGD YLIVNPFFHTFGYKAG +A+L+ Sbjct: 172 LFTSGTTGRPKGVMSGHQQNLRTFQAWSDAVGLREGDHYLIVNPFFHTFGYKAGWVAALL 231 Query: 224 RGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDK--AKLATLRAGVTGAA 281 +GAT+ PVA F+ ++ +A ER+T+LPGPPT++ SLL P + A A+LR VTGAA Sbjct: 232 QGATIFPVAQFNAAHVLATVAAERITVLPGPPTIFQSLLDEPARGAADTASLRLAVTGAA 291 Query: 282 DIPVELIRRIHEELPFETVATGYGLTE-AGTATLSRPGDSFTDIATTVGTACDGVEVNLA 340 +P LIRR+H+EL + V T YGLTE +G + ++ GD +A+T G GVEV L Sbjct: 292 SVPPVLIRRMHDELGIDEVLTAYGLTEGSGCVSATQAGDPVELVASTCGRPIPGVEVRLV 351 Query: 341 D----------DGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRII 390 D GE+LVRG++VM+GYLDDP ATAE ID DGWL TGD+ G LRI Sbjct: 352 DGAGRDVPAGEPGELLVRGFNVMKGYLDDPRATAETIDGDGWLRTGDIATQDARGYLRIT 411 Query: 391 GRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTR 450 R KD+FI GGFN YPAEIE LLEHPDVA+VAV+G D+RMG+VG A VV P G Sbjct: 412 DRAKDLFICGGFNCYPAEIEARLLEHPDVARVAVVGRPDERMGEVGHAVVV---PRPGAA 468 Query: 451 QCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 + + L+AW RE+MA YKVPR VE+++ELP+NA GKV + LK Sbjct: 469 R--DGKALLAWCREQMANYKVPRSVEWVDELPVNAAGKVQRFLLK 511 >tr|A4XFB5|A4XFB5_NOVAD Tax_Id=279238 SubName: Full=AMP-dependent synthetase and ligase;[Novosphingobium aromaticivorans] Length = 512 Score = 439 bits (1128), Expect = e-121 Identities = 242/525 (46%), Positives = 316/525 (60%), Gaps = 43/525 (8%) Query: 1 MTHPSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLA 60 M P TIP +AA + DA +V+++G+ +F EL R R AA A +A Sbjct: 1 MLDPLPATIPHAAQAAAATWPDAPSVLENGEV---------WSFAELWQRSRAAASALIA 51 Query: 61 HGIGRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQ 120 GI GDRVAIWAPNS EW++AA + G VV +NTR K EA D++RR+ A+++ Sbjct: 52 RGIKAGDRVAIWAPNSREWIVAAIATMACGAAVVTLNTRLKGREAGDILRRTNARLLFTV 111 Query: 121 QGFLGQDFE---VPAGVPAIE-----------IKSDFLASGEPAVVGGLRGTD---IADI 163 +GFLG D+ V +PA+E D +G+PAV + D ++DI Sbjct: 112 EGFLGIDYRALIVDEDLPALEGTVLLDREFDAFMRDGRGAGDPAVDAAMAQIDADTVSDI 171 Query: 164 VYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLI 223 ++TSGTTG PKGV+M + + L A WC L EGDRYLI NPFFH+FG K G +A ++ Sbjct: 172 LFTSGTTGSPKGVLMTYGRVLPQAAVWCANTRLTEGDRYLIANPFFHSFGMKVGWVACIL 231 Query: 224 RGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGAA 281 GA +P+ FDV ++LI ER+T +PGPPT++ LL DK K ++LR G TGAA Sbjct: 232 AGAVAVPMLQFDVGQAIDLIERERITFMPGPPTIFQMLLAELDKRKWDCSSLRGGTTGAA 291 Query: 282 DIPVELIRRIHEELPFETVATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLAD 341 +P L+ RI +L + T YG+TE T PGD IA T G A G EV +AD Sbjct: 292 TVPPALVERIRNDLGMVDLITAYGMTECVNITTCVPGDDAETIARTCGKAFPGNEVRIAD 351 Query: 342 D----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIG 391 + GEVLVRG VM GYLD+P ATAEAIDA GWLHTGD+G E G +RI Sbjct: 352 ENGNELPRGEAGEVLVRGQGVMLGYLDNPEATAEAIDAAGWLHTGDVGTMDERGYVRITD 411 Query: 392 RKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQ 451 R KD++I GGFN YPAE+E L EHP + AV+GV D+R+G+VG+AFVVLR T Sbjct: 412 RMKDLYISGGFNVYPAEVEKLLAEHPAIGMAAVVGVPDERLGEVGRAFVVLRPGASATE- 470 Query: 452 CVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKA 496 +L+AWSRE MA YKVPR +++LP NA+GKV+K L+A Sbjct: 471 ----AELVAWSRENMANYKVPRSFVLVDDLPRNASGKVLKTELRA 511 >tr|Q471M0|Q471M0_RALEJ Tax_Id=264198 SubName: Full=AMP-dependent synthetase and ligase;[Ralstonia eutropha] Length = 526 Score = 438 bits (1127), Expect = e-121 Identities = 253/529 (47%), Positives = 327/529 (61%), Gaps = 55/529 (10%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TIPE+V AA R+GD A+ + G LRL++ L +AA A +A G+ GD Sbjct: 10 TIPELVRRAAQRYGDRIAIQEDG---------LRLSYAALDASRIQAARALMALGVQPGD 60 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RVA+WAPN +EW+IAA + G +VP+NTR K EA V+ SGA+++ FLG+ Sbjct: 61 RVAMWAPNFSEWIIAALATHSVGAALVPLNTRMKGVEAGAVLADSGARLLFCVDDFLGES 120 Query: 128 FEV------PAGVPAIEIKSD---------------FLASGEPAVVGG-------LRGTD 159 + PA + + I FLA + + +RG Sbjct: 121 YPQMLAPHRPATLERLVILRPGHGRAAADGELPWEAFLALAQQVDMAAFAEREATVRGDM 180 Query: 160 IADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCI 219 DI++TSGTTGRPKGV+ H+Q LR W + ++ GDRYLIVNPFFHTFGYKAG + Sbjct: 181 PMDIMFTSGTTGRPKGVVTAHVQNLRAVDGWAAITGVQAGDRYLIVNPFFHTFGYKAGWL 240 Query: 220 ASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGV 277 A+L RGATVLP VFD +A++ + ER+T+LPGPPTLY +LL P + L++L V Sbjct: 241 AALSRGATVLPHLVFDAEAVMTRVENERITVLPGPPTLYQTLLNAPRLREFDLSSLCIAV 300 Query: 278 TGAADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVE 336 TGA+ I LI+R+ EL F+T+ TGYGLTE+ G ATL+R GD +A T G A G+E Sbjct: 301 TGASAIAPALIQRMRSELGFDTIITGYGLTESCGFATLTRAGDDADTVAATSGRAMPGIE 360 Query: 337 VNLAD----------DGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGR 386 + D GEVLVRGY+VMQGY P ATAEAIDADGWLHTGD+G G Sbjct: 361 IRCVDAQGRPVATGEPGEVLVRGYNVMQGYFSLPEATAEAIDADGWLHTGDVGTLDTRGY 420 Query: 387 LRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPL 446 LRI R KDMFIVGGFN YPAE+E L+ HP VAQVAV+G+ DR+G+VG+A+VVLR Sbjct: 421 LRITDRIKDMFIVGGFNCYPAEVEKLLVAHPAVAQVAVVGMPHDRLGEVGRAYVVLRH-- 478 Query: 447 DGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 G R V A+ LI W+R +MA YKVPR + F+ LP++A GKV+K L+ Sbjct: 479 -GAR--VDADTLIGWARRQMANYKVPREIVFVPTLPVSAAGKVLKYQLR 524 >tr|D0J3C6|D0J3C6_COMT2 Tax_Id=688245 SubName: Full=Long-chain-fatty-acid--CoA ligase;[Comamonas testosteroni] Length = 540 Score = 434 bits (1117), Expect = e-119 Identities = 243/525 (46%), Positives = 318/525 (60%), Gaps = 52/525 (9%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 T+P M+ RF D A+V++G + +++ +L R AA A ++ G+ GD Sbjct: 15 TLPGMLADVVSRFADRAAIVENGKS---------ISYAQLQQLSRLAARALMSLGVQAGD 65 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RVA+WAPN +EW++AA G AGGV+VP+NTR K EAAD++ RS A+V++ FL Sbjct: 66 RVALWAPNLSEWIVAACGVHAAGGVLVPLNTRMKGAEAADILERSRARVLVCVGDFLNNY 125 Query: 128 FEV------PAGVPAIEIKSD------------FLASGEPAVVGG-------LRGTDIAD 162 + P + + + D F+A + G ++ D AD Sbjct: 126 YPDLLNGLRPVTLQQVVVLGDKVLPSADMNWAQFMARADDTTAGAQQQREARIKPDDTAD 185 Query: 163 IVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASL 222 +++TSGTTGRPKGVM H T+ + W D+ L EG RYLIVNPFFHTFGYKAG +A+L Sbjct: 186 LMFTSGTTGRPKGVMCAHRPTILAFKAWSDVVGLTEGSRYLIVNPFFHTFGYKAGWVAAL 245 Query: 223 IRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGA 280 ++G+TV P VFD AI+ I ++R++ LPGPPTL+ S+L P L++L++ VTGA Sbjct: 246 LQGSTVYPEQVFDAQAILHRIESDRISFLPGPPTLFLSMLAHPGLKNFDLSSLKSSVTGA 305 Query: 281 ADIPVELIRRIHEELPFETVATGYGLTEAG-TATLSRPGDSFTDIATTVGTACDGVEVNL 339 + +P LI+R+ EEL V T YGLTE G ATL P D+ +A T G A G EV Sbjct: 306 STVPPILIKRMREELGIMNVTTAYGLTECGGCATLCEPSDNVETVANTCGKALPGTEVRC 365 Query: 340 ADD----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRI 389 D+ GEVL+RGY +MQGY +D ATAE IDADGWLHTGD+G E G LRI Sbjct: 366 VDEQGQPVAPGEAGEVLLRGYHIMQGYFEDEKATAETIDADGWLHTGDVGVLDERGYLRI 425 Query: 390 IGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGT 449 R KDMFIVGGFN YPAEIE L HP+VAQVAV+GV D+RMG+VG A VV R + Sbjct: 426 TDRLKDMFIVGGFNCYPAEIERMLSNHPEVAQVAVVGVADERMGEVGCACVVTRNGV--- 482 Query: 450 RQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHL 494 + E IAW R MA YKVPR+V L+ LP+NA+ KV K L Sbjct: 483 --TLDQEAFIAWCRANMANYKVPRFVLQLDGLPVNASNKVQKRDL 525 >tr|B7X423|B7X423_COMTE Tax_Id=399795 SubName: Full=AMP-dependent synthetase and ligase;[Comamonas testosteroni KF-1] Length = 540 Score = 434 bits (1116), Expect = e-119 Identities = 243/525 (46%), Positives = 320/525 (60%), Gaps = 52/525 (9%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 T+P M+ RF A+V+ G + +++ EL R+AA A ++ G+ GD Sbjct: 15 TLPGMLADVVSRFSTRAAIVESGKS---------ISYAELQQLSRQAARALMSLGVQAGD 65 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RVA+WAPN +EW++AA G AGGV+VP+NTR K EAADV+ RS A+V++ FL Sbjct: 66 RVALWAPNLSEWIVAACGVHAAGGVLVPLNTRMKGAEAADVLERSRARVLVCVGDFLNNY 125 Query: 128 FEV------PAGVPAIEIKSD------------FLASGEPAVV-------GGLRGTDIAD 162 + PA + + + D F+A E G++ D AD Sbjct: 126 YPDLLQGLRPATLEQVVVLGDKLLPSADLSWAQFMARAESTTAQAQQQREAGIKPDDTAD 185 Query: 163 IVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASL 222 +++TSGTTGRPKGVM H T+ + W ++ L EG RYLIVNPFFHTFGYKAG +A+L Sbjct: 186 LMFTSGTTGRPKGVMCAHRPTILAFKAWSEVVGLTEGSRYLIVNPFFHTFGYKAGWVAAL 245 Query: 223 IRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGA 280 ++G+TV P VFD AI++ I ++R++ LPGPPTL+ S+L P L++L++ VTGA Sbjct: 246 LQGSTVYPEQVFDAQAILQRIESDRISFLPGPPTLFLSMLAHPGLKDFDLSSLKSSVTGA 305 Query: 281 ADIPVELIRRIHEELPFETVATGYGLTEAG-TATLSRPGDSFTDIATTVGTACDGVEVNL 339 + +P LI+R+ EEL + V T YGLTE G ATL P D+ +A T G A G EV Sbjct: 306 STVPPILIKRMREELGIQNVTTAYGLTECGGCATLCEPADNVETVANTCGKALPGTEVRC 365 Query: 340 ADD----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRI 389 ++ GEVL+RGY +MQGY +D ATAE IDADGWLHTGD+G E G LRI Sbjct: 366 VNEQGQPVAPGEAGEVLLRGYHIMQGYFEDEKATAETIDADGWLHTGDVGVLDERGYLRI 425 Query: 390 IGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGT 449 R KDMFIVGGFN YPAEIE L HP+VAQVAV+GV D+RMG+VG A VV R + Sbjct: 426 TDRLKDMFIVGGFNCYPAEIERMLSNHPEVAQVAVVGVADERMGEVGCACVVARNGITLD 485 Query: 450 RQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHL 494 ++ T AW R MA YKVPR+V L+ LP+NA+ KV K L Sbjct: 486 KEAFT-----AWCRANMANYKVPRFVLQLDGLPVNASNKVQKRDL 525 >tr|A8M6H3|A8M6H3_SALAI Tax_Id=391037 SubName: Full=AMP-dependent synthetase and ligase;[Salinispora arenicola] Length = 508 Score = 428 bits (1101), Expect = e-118 Identities = 245/516 (47%), Positives = 319/516 (61%), Gaps = 38/516 (7%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 ++P +L AA FG A+V+ + L++ EL VRR A A +A G+ GD Sbjct: 4 SVPAALLRAARDFGTTPALVE--------PDVVHLSYEELLAEVRRVAQALIASGLRPGD 55 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 R+A+WAPNSA+W++ A G AG +VPVNTRF EA DVI RSGA ++ FLG D Sbjct: 56 RLALWAPNSAQWVLGALGGSYAGLTLVPVNTRFTGVEALDVIHRSGASGLVVVDPFLGTD 115 Query: 128 --------------------FEVPAGVPAIEIKSDFLASGEP-AVVGGLRGTDIADIVYT 166 VP+G +S + E A + D++D+++T Sbjct: 116 RLATLQAAATAEGRQLPRVIVRVPSGWDEFVSQSRAVPELEADACAAAVTPDDLSDVLFT 175 Query: 167 SGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGA 226 SGTTGR KGVM H Q++ + A W ++A L DRYL++NPFFH+FG KAG A L G+ Sbjct: 176 SGTTGRSKGVMSAHRQSMAVAAAWANIARLTPDDRYLVINPFFHSFGLKAGIFACLASGS 235 Query: 227 TVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGAADIP 284 ++P AVFDV + LIA +R+T+LPGPPTLY SLLG PD + L++LR VTGAA +P Sbjct: 236 AIVPQAVFDVPRTMALIADQRITVLPGPPTLYTSLLGYPDARRFDLSSLRLAVTGAATVP 295 Query: 285 VELIRRIHEELPFETVATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVEVNLAD-DG 343 L+ +I +EL + V T YGLTEA AT+ RPGD +A T G A G EV +AD G Sbjct: 296 PALVEQIRKELGAD-VLTAYGLTEAVVATMCRPGDDARTVAETCGRAAAGCEVRIADPGG 354 Query: 344 EVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFN 403 EVL+RG + M GYLDDP ATAEAIDA+GWLHTGD+G+ E G L I R KDM++ GGFN Sbjct: 355 EVLLRGPNTMLGYLDDPIATAEAIDAEGWLHTGDIGQLDEHGYLTITDRLKDMYVCGGFN 414 Query: 404 AYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSR 463 YPAE+E L + P VA+ AVIGV D R+G VGKA+VV R ++A ++I + R Sbjct: 415 VYPAEVERALAQLPGVAESAVIGVPDPRLGDVGKAYVVCR-----PGHSLSAAEVIEFCR 469 Query: 464 ERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAREA 499 R+A YKVPR VE ELP NA+GKV+K L+A A Sbjct: 470 SRLANYKVPRSVEVRSELPHNASGKVLKYLLRAESA 505 >tr|B4EKP2|B4EKP2_BURCJ Tax_Id=216591 SubName: Full=AMP-binding protein;[Burkholderia cepacia] Length = 526 Score = 427 bits (1098), Expect = e-117 Identities = 245/514 (47%), Positives = 311/514 (60%), Gaps = 46/514 (8%) Query: 23 AEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGDRVAIWAPNSAEWMIA 82 A A HG +PA + RLT+ EL AA A LA GI GDR+A+WAPN +W++A Sbjct: 13 ARAAARHGAHPAIESEHGRLTYAELDAARIDAARALLASGIDPGDRIAVWAPNLPQWIVA 72 Query: 83 AFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQDF-------------- 128 A T G V+VPVNTR K E V+ GA+++ FLG+ + Sbjct: 73 ALAIHTVGAVLVPVNTRMKGMEVGGVLHDGGARLLFCCGTFLGESYPAMLAPHRPATLER 132 Query: 129 ------EVPAGVPAIEIKSDFLASGEPAVVGGLRGTD-------IADIVYTSGTTGRPKG 175 E P+G E + FLA G + +R + + D+++TSGTTGRPKG Sbjct: 133 VVVFDGEPPSGAHD-ETWNAFLARGAAVPLAAVREREAQVTPDTVMDLMFTSGTTGRPKG 191 Query: 176 VMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFD 235 VM H Q LR W +A +R DRYLIVNPFFHTFGYKAG +A+L GATVLP VF Sbjct: 192 VMTAHGQNLRAAQAWAAIAGVRPDDRYLIVNPFFHTFGYKAGWLAALSSGATVLPHLVFQ 251 Query: 236 VDAIVELIATERVTMLPGPPTLYHSLLGVPDKA--KLATLRAGVTGAADIPVELIRRIHE 293 D ++ +A +RV++LPGPPTLY++LL PD+A L++LR VTGAA I LI R+ Sbjct: 252 PDDVLRRVAADRVSVLPGPPTLYYALLDAPDRATRDLSSLRIAVTGAAAIAPSLIERMRA 311 Query: 294 ELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVNLA----------DD 342 EL FETV TGYGLTE+ G ATL RPGD +A T G VE+ +A + Sbjct: 312 ELGFETVLTGYGLTESCGFATLCRPGDDAETVARTSGRPMPDVELRIAGPGGEPLGPDET 371 Query: 343 GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGF 402 GE+ VRGY+VM+GY + P AT E +DA GWLHTGDLG +G L+I R KDMFIVGGF Sbjct: 372 GEIWVRGYNVMRGYFNQPDATRETVDAAGWLHTGDLGCVDANGNLKITDRIKDMFIVGGF 431 Query: 403 NAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWS 462 N YPAEIE L HP +AQVA++GV D R+G+VG A+VVLR A++L W+ Sbjct: 432 NCYPAEIERLLAAHPAIAQVALVGVPDTRLGEVGHAYVVLRPGAH-----ADADELNDWA 486 Query: 463 RERMAGYKVPRYVEFLEELPLNATGKVMKDHLKA 496 R MA YKVPRY F+ +LP +A GKV+K L+A Sbjct: 487 RRNMANYKVPRYFTFVAQLPTSAAGKVLKYRLRA 520 >tr|Q1B2T6|Q1B2T6_MYCSS Tax_Id=164756 SubName: Full=AMP-dependent synthetase and ligase;[Mycobacterium sp.] Length = 506 Score = 427 bits (1097), Expect = e-117 Identities = 240/514 (46%), Positives = 314/514 (61%), Gaps = 37/514 (7%) Query: 7 QTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRG 66 +TIP ++ A++F D EAVV RLT+ +L D VRRAA A + GI G Sbjct: 6 RTIPAVLDRIAEQFSDHEAVV---------TDDRRLTYAQLRDEVRRAAAAMIDLGIAAG 56 Query: 67 DRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQ 126 DRVAIW+PN+ W++AA AGGVVVP+NTR+ A EA+D++ R+ A +++ FLG Sbjct: 57 DRVAIWSPNTWHWVVAALATTYAGGVVVPLNTRYTASEASDILARTAAPLLITAGKFLGA 116 Query: 127 DFEVP---AGVPAIE------------IKSDFLASGEP-----AVVGGLRGTDIADIVYT 166 D + +PA+ DF++ G A +R D+ADI++T Sbjct: 117 DRSADLDRSALPALRHIVRVPIETADGTWDDFVSRGTDLAAADARAAAVRPDDVADILFT 176 Query: 167 SGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGA 226 SGTTGR KGV+ H Q+L A W + L DRYL +NPFFH FGYKAG + L GA Sbjct: 177 SGTTGRSKGVLCAHRQSLDAPAAWAECGQLTSSDRYLCINPFFHNFGYKAGILTCLQTGA 236 Query: 227 TVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGAADIP 284 T++P FD + + +A +R+T+LPGPPT+Y ++L P +A+ L +LR VTGAA +P Sbjct: 237 TLIPQLTFDPEKAMAAVAEQRITVLPGPPTIYQTILDHPKRAEYDLTSLRFAVTGAAVVP 296 Query: 285 VELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVNLADDG 343 V LI R+ EL + V T YGLTEA G T+ R D +ATT G G E+ + D G Sbjct: 297 VVLIERMQSELDIDIVLTAYGLTEASGFGTMCRADDDAVTVATTCGRPIAGFELRIGDSG 356 Query: 344 EVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFN 403 EVL+RG +VM GYLDDP ATA AID DGWLHTGD+G E G LRI R KDM+I GGFN Sbjct: 357 EVLLRGPNVMLGYLDDPEATAAAIDPDGWLHTGDVGTVDERGNLRITDRLKDMYICGGFN 416 Query: 404 AYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSR 463 YPAEIE L VA+ AVIGV D+R+G+VGKAFVV + + Q V IA++R Sbjct: 417 VYPAEIEQVLARLDGVAESAVIGVPDERLGEVGKAFVVAKPGANLDEQAV-----IAYAR 471 Query: 464 ERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 + +A +K PR VEFL+ LP N GKV+K L+ R Sbjct: 472 DHLANFKTPRSVEFLDVLPRNPGGKVVKPLLRKR 505 >tr|A3Q6R6|A3Q6R6_MYCSJ Tax_Id=164757 SubName: Full=AMP-dependent synthetase and ligase;[Mycobacterium sp.] Length = 506 Score = 427 bits (1097), Expect = e-117 Identities = 240/514 (46%), Positives = 314/514 (61%), Gaps = 37/514 (7%) Query: 7 QTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRG 66 +TIP ++ A++F D EAVV RLT+ +L D VRRAA A + GI G Sbjct: 6 RTIPAVLDRIAEQFSDHEAVV---------TDDRRLTYAQLRDEVRRAAAAMIDLGIAAG 56 Query: 67 DRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQ 126 DRVAIW+PN+ W++AA AGGVVVP+NTR+ A EA+D++ R+ A +++ FLG Sbjct: 57 DRVAIWSPNTWHWVVAALATTYAGGVVVPLNTRYTASEASDILARTAAPLLITAGKFLGA 116 Query: 127 DFEVP---AGVPAIE------------IKSDFLASGEP-----AVVGGLRGTDIADIVYT 166 D + +PA+ DF++ G A +R D+ADI++T Sbjct: 117 DRSADLDRSALPALRHIVRVPIETADGTWDDFVSRGTDLAAADARAAAVRPDDVADILFT 176 Query: 167 SGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGA 226 SGTTGR KGV+ H Q+L A W + L DRYL +NPFFH FGYKAG + L GA Sbjct: 177 SGTTGRSKGVLCAHRQSLDAPAAWAECGQLTSSDRYLCINPFFHNFGYKAGILTCLQTGA 236 Query: 227 TVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGAADIP 284 T++P FD + + +A +R+T+LPGPPT+Y ++L P +A+ L +LR VTGAA +P Sbjct: 237 TLIPQLTFDPEKAMAAVAEQRITVLPGPPTIYQTILDHPKRAEYDLTSLRFAVTGAAVVP 296 Query: 285 VELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVNLADDG 343 V LI R+ EL + V T YGLTEA G T+ R D +ATT G G E+ + D G Sbjct: 297 VVLIERMQSELDIDIVLTAYGLTEASGFGTMCRADDDAVTVATTCGRPIAGFELRIGDSG 356 Query: 344 EVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFN 403 EVL+RG +VM GYLDDP ATA AID DGWLHTGD+G E G LRI R KDM+I GGFN Sbjct: 357 EVLLRGPNVMLGYLDDPEATAAAIDPDGWLHTGDVGTVDERGNLRITDRLKDMYICGGFN 416 Query: 404 AYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSR 463 YPAEIE L VA+ AVIGV D+R+G+VGKAFVV + + Q V IA++R Sbjct: 417 VYPAEIEQVLARLDGVAESAVIGVPDERLGEVGKAFVVAKPGANLDEQAV-----IAYAR 471 Query: 464 ERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 + +A +K PR VEFL+ LP N GKV+K L+ R Sbjct: 472 DHLANFKTPRSVEFLDVLPRNPGGKVVKPLLRKR 505 >tr|A1UMB2|A1UMB2_MYCSK Tax_Id=189918 SubName: Full=AMP-dependent synthetase and ligase;[Mycobacterium sp.] Length = 506 Score = 427 bits (1097), Expect = e-117 Identities = 240/514 (46%), Positives = 314/514 (61%), Gaps = 37/514 (7%) Query: 7 QTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRG 66 +TIP ++ A++F D EAVV RLT+ +L D VRRAA A + GI G Sbjct: 6 RTIPAVLDRIAEQFSDHEAVV---------TDDRRLTYAQLRDEVRRAAAAMIDLGIAAG 56 Query: 67 DRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQ 126 DRVAIW+PN+ W++AA AGGVVVP+NTR+ A EA+D++ R+ A +++ FLG Sbjct: 57 DRVAIWSPNTWHWVVAALATTYAGGVVVPLNTRYTASEASDILARTAAPLLITAGKFLGA 116 Query: 127 DFEVP---AGVPAIE------------IKSDFLASGEP-----AVVGGLRGTDIADIVYT 166 D + +PA+ DF++ G A +R D+ADI++T Sbjct: 117 DRSADLDRSALPALRHIVRVPIETADGTWDDFVSRGTDLAAADARAAAVRPDDVADILFT 176 Query: 167 SGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGA 226 SGTTGR KGV+ H Q+L A W + L DRYL +NPFFH FGYKAG + L GA Sbjct: 177 SGTTGRSKGVLCAHRQSLDAPAAWAECGQLTSSDRYLCINPFFHNFGYKAGILTCLQTGA 236 Query: 227 TVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGAADIP 284 T++P FD + + +A +R+T+LPGPPT+Y ++L P +A+ L +LR VTGAA +P Sbjct: 237 TLIPQLTFDPEKAMAAVAEQRITVLPGPPTIYQTILDHPKRAEYDLTSLRFAVTGAAVVP 296 Query: 285 VELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVNLADDG 343 V LI R+ EL + V T YGLTEA G T+ R D +ATT G G E+ + D G Sbjct: 297 VVLIERMQSELDIDIVLTAYGLTEASGFGTMCRADDDAVTVATTCGRPIAGFELRIGDSG 356 Query: 344 EVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFN 403 EVL+RG +VM GYLDDP ATA AID DGWLHTGD+G E G LRI R KDM+I GGFN Sbjct: 357 EVLLRGPNVMLGYLDDPEATAAAIDPDGWLHTGDVGTVDERGNLRITDRLKDMYICGGFN 416 Query: 404 AYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSR 463 YPAEIE L VA+ AVIGV D+R+G+VGKAFVV + + Q V IA++R Sbjct: 417 VYPAEIEQVLARLDGVAESAVIGVPDERLGEVGKAFVVAKPGANLDEQAV-----IAYAR 471 Query: 464 ERMAGYKVPRYVEFLEELPLNATGKVMKDHLKAR 497 + +A +K PR VEFL+ LP N GKV+K L+ R Sbjct: 472 DHLANFKTPRSVEFLDVLPRNPGGKVVKPLLRKR 505 >tr|A8H4F9|A8H4F9_SHEPA Tax_Id=398579 SubName: Full=AMP-dependent synthetase and ligase;[Shewanella pealeana] Length = 546 Score = 426 bits (1095), Expect = e-117 Identities = 234/532 (43%), Positives = 320/532 (60%), Gaps = 57/532 (10%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 TIP++VL AA+ + A+ D + ++++ ELA R + + +A G+ GD Sbjct: 25 TIPQLVLRAAELYNSDVAIEDDSE---------KISYAELATRALAVSKSLIAAGVTPGD 75 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RVAIW PN A W+IA+ G AG ++VP+NTR K EAAD++ RSG K++ FLG D Sbjct: 76 RVAIWLPNCANWVIASLGLQMAGAILVPLNTRMKPTEAADILARSGTKLLFVMGDFLGVD 135 Query: 128 FE------VPAGVPAIEIKS-----------------DFLASGEPAV-------VGGLRG 157 + +P V A I S FLA G ++ Sbjct: 136 YPAALAKLLPVNVEAQVIVSARAATSSNPLRLTQTWQQFLAMGNNQTSEIALERANAVKP 195 Query: 158 TDIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAG 217 DIAD+++TSGTTG+PKGVM +H L + ++ ++ + +GDRYL+VNPFFH FGYKAG Sbjct: 196 DDIADLMFTSGTTGKPKGVMSSHRSCLLAFTQFVEILGIEKGDRYLVVNPFFHAFGYKAG 255 Query: 218 CIASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVP--DKAKLATLRA 275 + LI GAT+LP VFD D ++E I +++++LPGPPTLY S+L P + L++LR Sbjct: 256 WLTCLIAGATILPHKVFDADEVIERIQKDKISVLPGPPTLYLSMLSHPKLEYTDLSSLRV 315 Query: 276 GVTGAADIPVELIRRIHEELPFETVATGYGLTE-AGTATLSRPGDSFTDIATTVGTACDG 334 VTGAA IP LI R+ EL F+ V T YGLTE G AT+ P + I+TT G+A G Sbjct: 316 AVTGAATIPPVLIERMRSELGFKIVTTAYGLTECGGLATICNPDEDVNTISTTSGSAIKG 375 Query: 335 VEVNLADD----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTES 384 ++++ + GE+ ++G+ VMQGY + ATAEAID D WLHTGD+G E Sbjct: 376 TQISIQSNSGQPLGIGVQGEICIKGFHVMQGYFQNATATAEAIDNDNWLHTGDIGMLDEC 435 Query: 385 GRLRIIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLRE 444 G L I GR KDMFIVGGFN YPAEIE L EH ++ AVIGV +RMG+VG A++V + Sbjct: 436 GNLTITGRLKDMFIVGGFNCYPAEIEAVLAEHDAISLSAVIGVPCERMGEVGCAYIVCK- 494 Query: 445 PLDGTRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLKA 496 + ++LI+WSRERMA YKVPR+V F+ LP+NA+ KV+K L A Sbjct: 495 ----LGHTINEQELISWSRERMANYKVPRHVRFVNSLPVNASNKVIKTALAA 542 >tr|Q7WSH3|Q7WSH3_COMTE Tax_Id=285 (ORF18)SubName: Full=ORF18 protein;[Comamonas testosteroni] Length = 540 Score = 426 bits (1095), Expect = e-117 Identities = 239/525 (45%), Positives = 315/525 (60%), Gaps = 52/525 (9%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 T+P M+ RF A+V++G + +++ +L R AA A ++ G+ GD Sbjct: 15 TLPGMLADVVSRFAGRAAIVENGKS---------ISYAQLQQLSRLAARALMSLGVQAGD 65 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 RVA+WAPN +EW++AA G AGGV+VP+NTR K EAAD++ RS A+V++ FL Sbjct: 66 RVALWAPNLSEWIVAACGVHAAGGVLVPLNTRMKGAEAADILERSRARVLVCVGDFLNNY 125 Query: 128 FEV------PAGVPAIEIKSD------------FLASGEPAVVGG-------LRGTDIAD 162 + P + + + D F+A + ++ D AD Sbjct: 126 YPDLLNGLRPVTLQQVVVLGDKVLPSADMNWAQFMARADGTTAEAQQQREARIKPDDTAD 185 Query: 163 IVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASL 222 +++TSGTTGRPKGVM H T+ + W D+ L EG RYLIVNPFFHTFGYKAG +A+L Sbjct: 186 LMFTSGTTGRPKGVMCAHRPTILAFKAWSDVVGLTEGSRYLIVNPFFHTFGYKAGWVAAL 245 Query: 223 IRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGA 280 ++G+TV P +FD AI+ I ++R++ LPGPPTL+ S+L P L++L++ VTGA Sbjct: 246 LQGSTVYPEQIFDAQAILHRIESDRISFLPGPPTLFLSMLAHPGLKNFDLSSLKSSVTGA 305 Query: 281 ADIPVELIRRIHEELPFETVATGYGLTEAG-TATLSRPGDSFTDIATTVGTACDGVEVNL 339 + +P LI+R+ EEL V T YGLTE G ATL P D+ +A T G A G EV Sbjct: 306 STVPPILIKRMREELGIMNVTTAYGLTECGGCATLCEPSDNVETVANTCGKALPGTEVRC 365 Query: 340 ADD----------GEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRI 389 D+ GEVL+RGY +MQGY +D AT E IDADGWLHTGD+G E G LRI Sbjct: 366 VDEQGRPVGPGEAGEVLLRGYHIMQGYFEDEKATEETIDADGWLHTGDVGVLDERGYLRI 425 Query: 390 IGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGT 449 R KDMFIVGGFN YPAEIE L HP+VAQVAV+GV D+RMG+VG A VV R + Sbjct: 426 TDRLKDMFIVGGFNCYPAEIERMLSNHPEVAQVAVVGVADERMGEVGCACVVTRNGV--- 482 Query: 450 RQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHL 494 + E IAW R MA YKVPR+V L+ LP+NA+ KV K L Sbjct: 483 --TLDQEAFIAWCRANMANYKVPRFVLQLDGLPVNASNKVQKRDL 525 >tr|Q396T0|Q396T0_BURS3 Tax_Id=269483 SubName: Full=AMP-dependent synthetase and ligase; EC=6.2.1.26;[Burkholderia sp.] Length = 528 Score = 424 bits (1090), Expect = e-116 Identities = 242/513 (47%), Positives = 311/513 (60%), Gaps = 44/513 (8%) Query: 23 AEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGDRVAIWAPNSAEWMIA 82 A A HG +PA + RLT+ EL AA A LA GI GDR+A+WAPN +W++A Sbjct: 15 ARAAARHGAHPAIESEHGRLTYAELDAARLDAARALLASGIAAGDRIAVWAPNLPQWIVA 74 Query: 83 AFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQDFEV------PAGVPA 136 A T G ++VPVNTR K E ++ GA+++ FLG+ + PA + Sbjct: 75 ALAIHTVGAILVPVNTRMKGMEVGGILHDGGARLLFCCGTFLGESYPAMLAPHRPATLER 134 Query: 137 I-------------EIKSDFLASGEPAVVGGLRGTD-------IADIVYTSGTTGRPKGV 176 + E S FLA G + +R + + D+++TSGTTGRPKGV Sbjct: 135 VVVFDGEPPSGAYDETWSAFLARGAEVPLVAVREREAQVTPDTVMDLMFTSGTTGRPKGV 194 Query: 177 MMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIASLIRGATVLPVAVFDV 236 M H Q LR W +A +R DRYLIVNPFFHTFGYKAG +A+L GATVLP VF Sbjct: 195 MTAHGQNLRAAQAWAAIAGVRPDDRYLIVNPFFHTFGYKAGWLAALSSGATVLPHLVFQP 254 Query: 237 DAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAGVTGAADIPVELIRRIHEE 294 ++ +A +RV++LPGPPTLY++LL PD+A L++LR VTGAA I LI R+ E Sbjct: 255 ADVLRRVADDRVSVLPGPPTLYYALLDAPDRATRDLSSLRIAVTGAAAIAPSLIERMRAE 314 Query: 295 LPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVNLA----------DDG 343 L FETV TGYGLTE+ G ATL R GD +A T G VE+ +A + G Sbjct: 315 LGFETVLTGYGLTESCGFATLCRQGDDAETVAYTSGRPMPDVELRIAGPGGEPLGPDETG 374 Query: 344 EVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDMFIVGGFN 403 E+ VRGY+VM+GY + P AT E +DADGWLHTGDLG +G L+I R KDMFIVGGFN Sbjct: 375 EIWVRGYNVMRGYFNQPDATRETVDADGWLHTGDLGCVDANGNLKITDRIKDMFIVGGFN 434 Query: 404 AYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAEDLIAWSR 463 YPAEIE L HP +AQVA++GV D R+G+VG A+VVLR A++L W+R Sbjct: 435 CYPAEIERLLAAHPAIAQVALVGVPDTRLGEVGHAYVVLRPGAQ-----ADADELNDWAR 489 Query: 464 ERMAGYKVPRYVEFLEELPLNATGKVMKDHLKA 496 MA YKVPR+ F+E+LP +A GKV+K L+A Sbjct: 490 RNMANYKVPRHFTFVEQLPTSAAGKVLKYRLRA 522 >tr|C1BAT4|C1BAT4_RHOOB Tax_Id=632772 SubName: Full=Putative fatty-acid--CoA ligase; EC=6.2.1.-;[Rhodococcus opacus] Length = 515 Score = 424 bits (1089), Expect = e-116 Identities = 234/524 (44%), Positives = 321/524 (61%), Gaps = 47/524 (8%) Query: 3 HPSWQTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHG 62 HP +TIP V AA +G+ AV D G +RLTF +L DRVR A A + G Sbjct: 4 HP--RTIPSAVTHAAREYGELLAVSD---------GDVRLTFTQLHDRVRDFAAALCSQG 52 Query: 63 IGRGDRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQG 122 + GD VA+W+PN+ W++AA G AG +VP+NTR+ A EA D++ R+ A ++ Sbjct: 53 VRPGDHVAVWSPNTYHWVVAALGIHYAGATLVPINTRYTAPEALDLLERTKATALVVAGM 112 Query: 123 FLGQD-----------------FEVP-----AGVPAIEIKSDFLA-------SGEPAVVG 153 FLG D VP A P + DFLA + A Sbjct: 113 FLGTDRYAALRDASGTLDLPTVVRVPVDGGDAPTPGVVDFDDFLALAGDDTRAEADARAA 172 Query: 154 GLRGTDIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFG 213 + D++D+++TSGTTGR KGVM H Q++ + W + A++ D YLI+NPFFHTFG Sbjct: 173 AVSPDDVSDVMFTSGTTGRSKGVMSAHRQSVGIARAWGECAEVTPEDNYLIINPFFHTFG 232 Query: 214 YKAGCIASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LA 271 YKAG + L+ G TV+P+AVFDV ++ + E++T+LPG PT++ S+L PD+ + L+ Sbjct: 233 YKAGFLVCLLNGVTVVPMAVFDVPKVMATVHDEQITVLPGAPTIFQSILDHPDRPEYDLS 292 Query: 272 TLRAGVTGAADIPVELIRRIHEELPFETVATGYGLTEAGTATLSRPGDSFTDIATTVGTA 331 +LR +TGAA +PV L+ R+ EL F+ V T YG TEA T+ R D ++TT G A Sbjct: 293 SLRVAITGAAAVPVALVERMQSELSFDAVLTAYGQTEAVVVTMCRTDDDPVTVSTTSGRA 352 Query: 332 CDGVEVNLADDGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIG 391 G+EV + D GE+LVRG +VM GYLDDP +TA+ IDADGWLHTGD+G + G + I Sbjct: 353 IPGMEVRIGDHGEILVRGENVMLGYLDDPESTAKTIDADGWLHTGDVGTLDDRGYVDITD 412 Query: 392 RKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQ 451 R KDM+I GGFN YPAE+E L VA+ AVIGV D RMG+VG+AFVV + GT Sbjct: 413 RLKDMYISGGFNVYPAEVENALARLDGVAESAVIGVPDQRMGEVGRAFVVAKA---GT-- 467 Query: 452 CVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 + +D+IA+ +ER+AG+KVPR V F++ LP N +GKVMK+ L+ Sbjct: 468 ALAEDDVIAFCKERLAGFKVPRSVRFVDSLPRNPSGKVMKNVLR 511 >tr|B7S1X5|B7S1X5_9GAMM Tax_Id=247634 (fadD)SubName: Full=AMP-binding enzyme, putative;[marine gamma proteobacterium HTCC2148] Length = 528 Score = 424 bits (1089), Expect = e-116 Identities = 232/527 (44%), Positives = 326/527 (61%), Gaps = 54/527 (10%) Query: 7 QTIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRG 66 +T+P++V +A +GD A+ D G ++LT+ +L R+AA AF+A G+ +G Sbjct: 9 RTLPQLVAQSAQAYGDRVAITD---------GDVQLTYQQLDAARRQAARAFMAAGLAQG 59 Query: 67 DRVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQ 126 +R+AIWAPN +W+IAA GA + G V+VP+NTR K EA ++R S ++++ FLG Sbjct: 60 ERIAIWAPNIYQWIIAAIGAQSVGVVLVPLNTRMKGAEAGYILRASQSRLLFTVADFLGV 119 Query: 127 DFEVPAGVPAIEIK------------------SDFLASGEPAVVG-------GLRGTDIA 161 ++ PA + + E+ +DF+ +GE L D Sbjct: 120 NY--PALLASEELPELRNTILLEGQADGTQSWADFITAGEVIADAEVTERSDALTPDDTL 177 Query: 162 DIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGCIAS 221 DI++TSGTTG PKGV+ H Q +R + W LR+ D YL++NPFFH+FGYKAG +A Sbjct: 178 DILFTSGTTGNPKGVVTCHGQNIRTFENWSATVGLRKDDNYLVINPFFHSFGYKAGWLAC 237 Query: 222 LIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKA--KLATLRAGVTG 279 +IRGA +LPV FD+DA++ I ++RV+M+PGPPT+Y SLL P+++ L++LR VTG Sbjct: 238 IIRGAHILPVKSFDLDAVMSQIQSDRVSMIPGPPTIYQSLLAHPNRSDYDLSSLRLAVTG 297 Query: 280 AADIPVELIRRIHEELPFETVATGYGLTEA-GTATLSRPGDSFTDIATTVGTACDGVEVN 338 AA +PV L+ ++ +EL FE V T YGLTE+ G ++ R DS I+ T G A +GVE+ Sbjct: 298 AAPVPVALVEQMRKELGFEVVVTAYGLTESCGVVSICRADDSAQRISHTSGRAMEGVEMK 357 Query: 339 LAD----------DGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLR 388 L D +GE+ RG++VMQGYLDDP TA AI DGWL TGD+G G +R Sbjct: 358 LVDNHGQEVSVGNEGEIWFRGFNVMQGYLDDPEQTALAITPDGWLKTGDVGVMDADGYVR 417 Query: 389 IIGRKKDMFIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDG 448 I R KDMFIVGGFN YPAEIE L P +A+ AVIGV D RMG+V A++V Sbjct: 418 ITDRIKDMFIVGGFNTYPAEIENILCSMPGIARAAVIGVPDARMGEVAHAYIV-----PA 472 Query: 449 TRQCVTAEDLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 + + +IAW+++ MA YKVPR V F+ ELP+NA GKV+K+ L+ Sbjct: 473 ADEAIDEAAVIAWAKDNMANYKVPRTVSFIAELPMNAGGKVLKNELR 519 >tr|Q0S7V5|Q0S7V5_RHOSR Tax_Id=101510 SubName: Full=CoA ligase; EC=6.2.1.-;[Rhodococcus sp.] Length = 515 Score = 422 bits (1086), Expect = e-116 Identities = 226/519 (43%), Positives = 318/519 (61%), Gaps = 45/519 (8%) Query: 8 TIPEMVLSAADRFGDAEAVVDHGDNPAGAAGPLRLTFVELADRVRRAAGAFLAHGIGRGD 67 T P + AA FG+ AV D G +RLTF +L DRVR A A + + GD Sbjct: 7 TTPSALKRAAREFGELTAVAD---------GDVRLTFTQLHDRVRDFAAALSSQDVRPGD 57 Query: 68 RVAIWAPNSAEWMIAAFGALTAGGVVVPVNTRFKAEEAADVIRRSGAKVVLRQQGFLGQD 127 VA+W+PN+ W++AA G AG +VP+NTR+ A EA D++ R+ ++ FLG D Sbjct: 58 HVAVWSPNTYHWVVAALGIHYAGATLVPINTRYTATEALDILERTKTTALVVAGNFLGTD 117 Query: 128 -----------FEVP-----------AGVPAIEIKSDFLASGEP-------AVVGGLRGT 158 F++P A +P + DFLA + A + Sbjct: 118 RYASLRDESSTFDLPTVVRVPVDGGDAELPGVFDFDDFLALADEDTRAEADARAAAVSPD 177 Query: 159 DIADIVYTSGTTGRPKGVMMNHLQTLRLYAEWCDLADLREGDRYLIVNPFFHTFGYKAGC 218 D++D+++TSGTTGR KGVM H Q++ + W + A++ D YLI+NPFFHTFGYKAG Sbjct: 178 DVSDVMFTSGTTGRSKGVMSAHRQSVGIAQAWGECAEVTSDDNYLIINPFFHTFGYKAGF 237 Query: 219 IASLIRGATVLPVAVFDVDAIVELIATERVTMLPGPPTLYHSLLGVPDKAK--LATLRAG 276 + L+ GATV+P+AVFDV ++ + E++T+LPG PT++ S+L PD+ K L++LR Sbjct: 238 LVCLLNGATVVPMAVFDVPKVMATVHDEQITVLPGAPTIFQSILDHPDRPKYDLSSLRVA 297 Query: 277 VTGAADIPVELIRRIHEELPFETVATGYGLTEAGTATLSRPGDSFTDIATTVGTACDGVE 336 +TGAA +PV L+ R+ EL F+ V T YG TEA T+ R D ++TT G A G+E Sbjct: 298 ITGAAAVPVALVERMQSELSFDAVLTAYGQTEAVVVTMCRTDDDPVTVSTTSGRAIPGME 357 Query: 337 VNLADDGEVLVRGYSVMQGYLDDPAATAEAIDADGWLHTGDLGEFTESGRLRIIGRKKDM 396 V + D GE+LVRG +VM GYLDDP +TA+ IDADGWLHTGD+G + G + I R KDM Sbjct: 358 VRIGDQGEILVRGENVMLGYLDDPESTAKTIDADGWLHTGDVGTLDDRGYVDITDRLKDM 417 Query: 397 FIVGGFNAYPAEIEGFLLEHPDVAQVAVIGVDDDRMGQVGKAFVVLREPLDGTRQCVTAE 456 +I GGFN YPAE+E L VA+ AVIGV D+RMG+VG+A+VV + + + + Sbjct: 418 YISGGFNVYPAEVENALARLDGVAESAVIGVPDERMGEVGRAYVVAKPGV-----TLAED 472 Query: 457 DLIAWSRERMAGYKVPRYVEFLEELPLNATGKVMKDHLK 495 D++A+ +ER+A +KVPR V F++ LP N +GKVMK+ L+ Sbjct: 473 DVVAFCKERLANFKVPRSVRFVDSLPRNPSGKVMKNVLR 511 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.320 0.138 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 4,337,511,077 Number of extensions: 193499457 Number of successful extensions: 598146 Number of sequences better than 10.0: 28610 Number of HSP's gapped: 517479 Number of HSP's successfully gapped: 42531 Length of query: 503 Length of database: 4,236,830,644 Length adjustment: 142 Effective length of query: 361 Effective length of database: 2,460,713,956 Effective search space: 888317738116 Effective search space used: 888317738116 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 83 (36.6 bits)