BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_5249
         (490 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|A0R2V7|A0R2V7_MYCS2 Tax_Id=246196 (glyA)RecName: Full=Serine ...   881   0.0  
tr|A4T9B1|A4T9B1_MYCGI Tax_Id=350054 RecName: Full=Serine hydrox...   805   0.0  
tr|Q1B4E8|Q1B4E8_MYCSS Tax_Id=164756 RecName: Full=Serine hydrox...   801   0.0  
tr|A3Q4Q6|A3Q4Q6_MYCSJ Tax_Id=164757 RecName: Full=Serine hydrox...   801   0.0  
tr|A1UKP0|A1UKP0_MYCSK Tax_Id=189918 RecName: Full=Serine hydrox...   801   0.0  
tr|A1TE31|A1TE31_MYCVP Tax_Id=350058 RecName: Full=Serine hydrox...   800   0.0  
tr|B1MKN2|B1MKN2_MYCA9 Tax_Id=561007 RecName: Full=Serine hydrox...   778   0.0  
tr|A1SJ72|A1SJ72_NOCSJ Tax_Id=196162 RecName: Full=Serine hydrox...   739   0.0  
tr|D2SAA3|D2SAA3_GEOOG Tax_Id=526225 RecName: Full=Serine hydrox...   710   0.0  
tr|D2PKS4|D2PKS4_KRIFD Tax_Id=479435 RecName: Full=Serine hydrox...   704   0.0  
sp|Q6AAU3|GLYA_PROAC Tax_Id=1747 (glyA)RecName: Full=Serine hydr...   678   0.0  
tr|D4HB50|D4HB50_PROAS Tax_Id=553199 (glyA)RecName: Full=Serine ...   678   0.0  
tr|D3MHV2|D3MHV2_PROAC Tax_Id=686659 RecName: Full=Serine hydrox...   678   0.0  
tr|D3MHI1|D3MHI1_PROAC Tax_Id=679195 RecName: Full=Serine hydrox...   678   0.0  
tr|D1YAB0|D1YAB0_PROAC Tax_Id=679194 (glyA)RecName: Full=Serine ...   673   0.0  
sp|A8M1D3|GLYA_SALAI Tax_Id=391037 (glyA)RecName: Full=Serine hy...   664   0.0  
tr|D1S2F3|D1S2F3_9ACTO Tax_Id=644283 RecName: Full=Serine hydrox...   662   0.0  
tr|D3CEU5|D3CEU5_9ACTO Tax_Id=648999 RecName: Full=Serine hydrox...   662   0.0  
sp|A4X6P4|GLYA_SALTO Tax_Id=369723 (glyA)RecName: Full=Serine hy...   658   0.0  
tr|C4RDT9|C4RDT9_9ACTO Tax_Id=219305 RecName: Full=Serine hydrox...   652   0.0  
tr|D6KC91|D6KC91_9ACTO Tax_Id=645465 SubName: Full=Serine hydrox...   642   0.0  
tr|C9YTF8|C9YTF8_STRSW Tax_Id=680198 (glyA1)RecName: Full=Serine...   641   0.0  
tr|Q9KZA9|Q9KZA9_STRCO Tax_Id=1902 RecName: Full=Serine hydroxym...   638   0.0  
tr|D6ECN5|D6ECN5_STRLI Tax_Id=457428 SubName: Full=Serine hydrox...   638   0.0  
tr|Q82HT9|Q82HT9_STRAW Tax_Id=33903 (glyA3)RecName: Full=Serine ...   636   e-180
tr|B5HVC0|B5HVC0_9ACTO Tax_Id=463191 RecName: Full=Serine hydrox...   634   e-179
tr|D6A1Z6|D6A1Z6_9ACTO Tax_Id=566461 SubName: Full=Serine hydrox...   631   e-179
tr|B5GB19|B5GB19_9ACTO Tax_Id=465543 RecName: Full=Serine hydrox...   597   e-169
sp|O83349|GLYA_TREPA Tax_Id=160 (glyA)RecName: Full=Serine hydro...   498   e-139
tr|B2S2S6|B2S2S6_TREPS Tax_Id=455434 (glyA)RecName: Full=Serine ...   498   e-139
tr|Q6ME31|Q6ME31_PARUW Tax_Id=264201 (glyA)RecName: Full=Serine ...   483   e-134
tr|D1R7V4|D1R7V4_9CHLA Tax_Id=159254 RecName: Full=Serine hydrox...   482   e-134
tr|A6DLM4|A6DLM4_9BACT Tax_Id=313628 SubName: Full=Serine hydrox...   480   e-133
tr|B5JM10|B5JM10_9BACT Tax_Id=382464 RecName: Full=Serine hydrox...   469   e-130
tr|Q73JA7|Q73JA7_TREDE Tax_Id=158 (glyA)RecName: Full=Serine hyd...   459   e-127
sp|B0BC69|GLYA_CHLTB Tax_Id=471473 (glyA)RecName: Full=Serine hy...   434   e-119
sp|B0B804|GLYA_CHLT2 Tax_Id=471472 (glyA)RecName: Full=Serine hy...   434   e-119
tr|D3UUP9|D3UUP9_CHLTS Tax_Id=634464 (glyA)RecName: Full=Serine ...   434   e-119
sp|O84439|GLYA_CHLTR Tax_Id=813 (glyA)RecName: Full=Serine hydro...   433   e-119
sp|Q3KLR8|GLYA_CHLTA Tax_Id=315277 (glyA)RecName: Full=Serine hy...   433   e-119
tr|C4PRB0|C4PRB0_CHLTJ Tax_Id=580049 (glyA)RecName: Full=Serine ...   433   e-119
tr|C4PMU1|C4PMU1_CHLTZ Tax_Id=672161 (glyA)RecName: Full=Serine ...   433   e-119
sp|Q5L6P4|GLYA_CHLAB Tax_Id=83555 (glyA)RecName: Full=Serine hyd...   424   e-116
sp|Q824C8|GLYA_CHLCV Tax_Id=83557 (glyA)RecName: Full=Serine hyd...   423   e-116
sp|Q9PJW0|GLYA_CHLMU Tax_Id=83560 (glyA)RecName: Full=Serine hyd...   422   e-116

>tr|A0R2V7|A0R2V7_MYCS2 Tax_Id=246196 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Mycobacterium
           smegmatis]
          Length = 490

 Score =  881 bits (2277), Expect = 0.0
 Identities = 444/459 (96%), Positives = 444/459 (96%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF
Sbjct: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA
Sbjct: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF
Sbjct: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPVPHAHV     HKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVM    
Sbjct: 272 FTGDEDPVPHAHVTTTTTHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMAAKA 331

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 RQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA
Sbjct: 332 VALAEARQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT
Sbjct: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451

Query: 452 QPEGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           QPEGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL
Sbjct: 452 QPEGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490


>tr|A4T9B1|A4T9B1_MYCGI Tax_Id=350054 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Mycobacterium
           gilvum]
          Length = 487

 Score =  805 bits (2078), Expect = 0.0
 Identities = 398/463 (85%), Positives = 423/463 (91%), Gaps = 4/463 (0%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+VIE+VEPR+A ATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGT+GHRF
Sbjct: 25  LRVIETVEPRIAEATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTVGHRF 84

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YA CQNVDTVE++AAEHARELFGAPYAY QPHSGIDANLVA+WAILATRVEAP LA  GA
Sbjct: 85  YAACQNVDTVEALAAEHARELFGAPYAYAQPHSGIDANLVAYWAILATRVEAPGLAEMGA 144

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           KHINDLSEADWE LR KLGNQRLLGMSLD GGHLTHGFRPNISGKMFHQR YGT+P TGF
Sbjct: 145 KHINDLSEADWEKLRAKLGNQRLLGMSLDTGGHLTHGFRPNISGKMFHQRQYGTDPTTGF 204

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYDAVAA+AREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 205 IDYDAVAASAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 264

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPVPHAHV     HKSLRGPRGG+VLATEE+APAVDKGCPMVLGGPLSHVM    
Sbjct: 265 FTGDEDPVPHAHVVTTTTHKSLRGPRGGLVLATEEFAPAVDKGCPMVLGGPLSHVMAAKA 324

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 RQP F+ YAQ VADNAQ LADGFVKRDAGLVTGGTDNH+VLLDVTSFGLTGRQA
Sbjct: 325 VALAEARQPEFRTYAQAVADNAQTLADGFVKRDAGLVTGGTDNHLVLLDVTSFGLTGRQA 384

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLD+GIVTNRN+IPADPNGAWYTSG+R G+PALT+RGFGAD+FDRV+EL+VEVL+NT
Sbjct: 385 ESALLDSGIVTNRNAIPADPNGAWYTSGIRFGSPALTTRGFGADEFDRVSELVVEVLSNT 444

Query: 452 Q----PEGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           Q    P G SKAKY +ADG AERVHAA+SELL ANPLYPGLTL
Sbjct: 445 QPAAGPNGPSKAKYTIADGVAERVHAAASELLEANPLYPGLTL 487


>tr|Q1B4E8|Q1B4E8_MYCSS Tax_Id=164756 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1; Flags:
           Precursor;[Mycobacterium sp.]
          Length = 492

 Score =  801 bits (2069), Expect = 0.0
 Identities = 399/464 (85%), Positives = 422/464 (90%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           LQVIESVEPR+AAATRKELADQRDSLKLIASENYASPAVLLTMGTW SDKYAEGTIGHRF
Sbjct: 29  LQVIESVEPRIAAATRKELADQRDSLKLIASENYASPAVLLTMGTWLSDKYAEGTIGHRF 88

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVD VESVAAEHARELFGAPYAY QPHSGIDANLVAFWAILATRVEAP LA  GA
Sbjct: 89  YAGCQNVDVVESVAAEHARELFGAPYAYAQPHSGIDANLVAFWAILATRVEAPGLAELGA 148

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           KH+NDLSEADWE+LRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGT+PETG 
Sbjct: 149 KHVNDLSEADWESLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTDPETGL 208

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD +AAAAREFKPL+LV GYSAYPRRVNFAK+REIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 209 LDYDKLAAAAREFKPLILVGGYSAYPRRVNFAKLREIADEVGATLMVDMAHFAGLVAGKV 268

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPVPHAHV     HKSLRGPRGG+VLA  EY+ AVDKGCPMVLGGPLSHVM    
Sbjct: 269 FTGDEDPVPHAHVVTTTTHKSLRGPRGGLVLAQPEYSDAVDKGCPMVLGGPLSHVMAAKA 328

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 RQP+FQ YAQ+VADNA++LA+GF+KR A LVTGGTDNHIVLLDVTSFGLTGRQA
Sbjct: 329 VALAEARQPSFQAYAQRVADNAKSLAEGFLKRGARLVTGGTDNHIVLLDVTSFGLTGRQA 388

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLDAG+VTNRNSIPADPNGAWYTSG+R GTPALT+RGFGA +FDRVAEL+V+VL NT
Sbjct: 389 ESALLDAGVVTNRNSIPADPNGAWYTSGIRFGTPALTTRGFGAAEFDRVAELVVDVLNNT 448

Query: 452 QPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           QP  T     SKAKY LADGTAERVHAAS+E+L ANPLYPGLTL
Sbjct: 449 QPNSTGPTGFSKAKYTLADGTAERVHAASAEMLDANPLYPGLTL 492


>tr|A3Q4Q6|A3Q4Q6_MYCSJ Tax_Id=164757 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Mycobacterium sp.]
          Length = 492

 Score =  801 bits (2069), Expect = 0.0
 Identities = 399/464 (85%), Positives = 422/464 (90%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           LQVIESVEPR+AAATRKELADQRDSLKLIASENYASPAVLLTMGTW SDKYAEGTIGHRF
Sbjct: 29  LQVIESVEPRIAAATRKELADQRDSLKLIASENYASPAVLLTMGTWLSDKYAEGTIGHRF 88

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVD VESVAAEHARELFGAPYAY QPHSGIDANLVAFWAILATRVEAP LA  GA
Sbjct: 89  YAGCQNVDVVESVAAEHARELFGAPYAYAQPHSGIDANLVAFWAILATRVEAPGLAELGA 148

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           KH+NDLSEADWE+LRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGT+PETG 
Sbjct: 149 KHVNDLSEADWESLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTDPETGL 208

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD +AAAAREFKPL+LV GYSAYPRRVNFAK+REIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 209 LDYDKLAAAAREFKPLILVGGYSAYPRRVNFAKLREIADEVGATLMVDMAHFAGLVAGKV 268

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPVPHAHV     HKSLRGPRGG+VLA  EY+ AVDKGCPMVLGGPLSHVM    
Sbjct: 269 FTGDEDPVPHAHVVTTTTHKSLRGPRGGLVLAQPEYSDAVDKGCPMVLGGPLSHVMAAKA 328

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 RQP+FQ YAQ+VADNA++LA+GF+KR A LVTGGTDNHIVLLDVTSFGLTGRQA
Sbjct: 329 VALAEARQPSFQAYAQRVADNAKSLAEGFLKRGARLVTGGTDNHIVLLDVTSFGLTGRQA 388

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLDAG+VTNRNSIPADPNGAWYTSG+R GTPALT+RGFGA +FDRVAEL+V+VL NT
Sbjct: 389 ESALLDAGVVTNRNSIPADPNGAWYTSGIRFGTPALTTRGFGAAEFDRVAELVVDVLNNT 448

Query: 452 QPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           QP  T     SKAKY LADGTAERVHAAS+E+L ANPLYPGLTL
Sbjct: 449 QPNSTGPTGFSKAKYTLADGTAERVHAASAEMLDANPLYPGLTL 492


>tr|A1UKP0|A1UKP0_MYCSK Tax_Id=189918 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Mycobacterium sp.]
          Length = 492

 Score =  801 bits (2069), Expect = 0.0
 Identities = 399/464 (85%), Positives = 422/464 (90%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           LQVIESVEPR+AAATRKELADQRDSLKLIASENYASPAVLLTMGTW SDKYAEGTIGHRF
Sbjct: 29  LQVIESVEPRIAAATRKELADQRDSLKLIASENYASPAVLLTMGTWLSDKYAEGTIGHRF 88

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVD VESVAAEHARELFGAPYAY QPHSGIDANLVAFWAILATRVEAP LA  GA
Sbjct: 89  YAGCQNVDVVESVAAEHARELFGAPYAYAQPHSGIDANLVAFWAILATRVEAPGLAELGA 148

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           KH+NDLSEADWE+LRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGT+PETG 
Sbjct: 149 KHVNDLSEADWESLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTDPETGL 208

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD +AAAAREFKPL+LV GYSAYPRRVNFAK+REIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 209 LDYDKLAAAAREFKPLILVGGYSAYPRRVNFAKLREIADEVGATLMVDMAHFAGLVAGKV 268

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPVPHAHV     HKSLRGPRGG+VLA  EY+ AVDKGCPMVLGGPLSHVM    
Sbjct: 269 FTGDEDPVPHAHVVTTTTHKSLRGPRGGLVLAQPEYSDAVDKGCPMVLGGPLSHVMAAKA 328

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 RQP+FQ YAQ+VADNA++LA+GF+KR A LVTGGTDNHIVLLDVTSFGLTGRQA
Sbjct: 329 VALAEARQPSFQAYAQRVADNAKSLAEGFLKRGARLVTGGTDNHIVLLDVTSFGLTGRQA 388

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLDAG+VTNRNSIPADPNGAWYTSG+R GTPALT+RGFGA +FDRVAEL+V+VL NT
Sbjct: 389 ESALLDAGVVTNRNSIPADPNGAWYTSGIRFGTPALTTRGFGAAEFDRVAELVVDVLNNT 448

Query: 452 QPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           QP  T     SKAKY LADGTAERVHAAS+E+L ANPLYPGLTL
Sbjct: 449 QPNSTGPTGFSKAKYTLADGTAERVHAASAEMLDANPLYPGLTL 492


>tr|A1TE31|A1TE31_MYCVP Tax_Id=350058 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Mycobacterium
           vanbaalenii]
          Length = 487

 Score =  800 bits (2067), Expect = 0.0
 Identities = 396/463 (85%), Positives = 420/463 (90%), Gaps = 4/463 (0%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+VIESVEPRVA ATRKELADQR SLKLIASENYASPAVLLTMGTWFSDKYAEGT+GHRF
Sbjct: 25  LRVIESVEPRVAEATRKELADQRGSLKLIASENYASPAVLLTMGTWFSDKYAEGTVGHRF 84

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YA CQNVDTVE++AAEHARELFGAPYAY QPHSGIDANLVA+WAILATRVEAP LA  GA
Sbjct: 85  YAACQNVDTVEALAAEHARELFGAPYAYAQPHSGIDANLVAYWAILATRVEAPGLAELGA 144

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           KH+NDLSE DWE LR KLGNQRLLGMSLD GGHLTHGFRPNISGKMFHQR YGT+P TGF
Sbjct: 145 KHVNDLSEGDWEKLRAKLGNQRLLGMSLDTGGHLTHGFRPNISGKMFHQRQYGTDPATGF 204

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 205 IDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 264

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPVPHAH+     HKSLRGPRGG+VLATEEYAPAVDKGCPMVLGGPLSHVM    
Sbjct: 265 FTGDEDPVPHAHITTTTTHKSLRGPRGGLVLATEEYAPAVDKGCPMVLGGPLSHVMAAKA 324

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+P F+ YAQ VADNAQALADGF+KRD  LVTGGTDNH+VLLDVTSFGLTGRQA
Sbjct: 325 VALAEARRPEFRAYAQAVADNAQALADGFIKRDGSLVTGGTDNHLVLLDVTSFGLTGRQA 384

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLD+GIVTNRN++PADPNGAWYTSG+R G+PALT+RGFGADDFDRVAEL+VEVL+NT
Sbjct: 385 ESALLDSGIVTNRNAVPADPNGAWYTSGIRFGSPALTTRGFGADDFDRVAELVVEVLSNT 444

Query: 452 Q----PEGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           Q    P G SKAKY LADGTAERV AA++ELL ANPLYPGLTL
Sbjct: 445 QPAAGPNGPSKAKYTLADGTAERVRAAAAELLDANPLYPGLTL 487


>tr|B1MKN2|B1MKN2_MYCA9 Tax_Id=561007 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Mycobacterium
           abscessus]
          Length = 485

 Score =  778 bits (2009), Expect = 0.0
 Identities = 379/459 (82%), Positives = 419/459 (91%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           LQVIE++EPR+A ATRKELADQRDSLKLIASENYASPAVLLTMGTW SDKYAEGTIGHRF
Sbjct: 27  LQVIETIEPRIADATRKELADQRDSLKLIASENYASPAVLLTMGTWLSDKYAEGTIGHRF 86

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQN+DTVE++AAEHARELFGAPYAY QPHSGIDANLVA+WAILATRVEAP LA+ G 
Sbjct: 87  YAGCQNIDTVEALAAEHARELFGAPYAYAQPHSGIDANLVAYWAILATRVEAPALADKGV 146

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           +++NDLSE DWE LR++ GNQRL+GMSLDAGGHLTHGFRPNISGKMFHQRSYGT+PETG 
Sbjct: 147 RNVNDLSETDWEELRHQYGNQRLMGMSLDAGGHLTHGFRPNISGKMFHQRSYGTDPETGL 206

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYDA+AAAAREFKPLVLV GYSAYPRRVNFAK+REIADEVGATL VDMAHFAGLVAGKV
Sbjct: 207 LDYDALAAAAREFKPLVLVGGYSAYPRRVNFAKLREIADEVGATLFVDMAHFAGLVAGKV 266

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDE+PVPHAH+     HKSLRGPRGG+VLAT EY+ AVDKGCPMVLGGPLSHVM    
Sbjct: 267 FTGDENPVPHAHITTTTTHKSLRGPRGGLVLATAEYSDAVDKGCPMVLGGPLSHVMAAKA 326

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 RQP+FQ YAQ+VADNA++LA+GF+KR A LVTGGTDNH+VLLDV SFGLTGRQA
Sbjct: 327 VALAEARQPSFQAYAQRVADNAKSLAEGFLKRGARLVTGGTDNHLVLLDVQSFGLTGRQA 386

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLDAG+VTNRN+IPADPNGAWYTSG+R GTPALTSRGFGAD+FD+VAEL+V+VL NT
Sbjct: 387 ESALLDAGVVTNRNAIPADPNGAWYTSGIRFGTPALTSRGFGADEFDKVAELVVDVLTNT 446

Query: 452 QPEGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           + +G+SKAKY LAD  AERV AAS+ELL+ANPLYPGLTL
Sbjct: 447 EADGSSKAKYTLADAVAERVKAASAELLAANPLYPGLTL 485


>tr|A1SJ72|A1SJ72_NOCSJ Tax_Id=196162 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Nocardioides sp.]
          Length = 482

 Score =  739 bits (1908), Expect = 0.0
 Identities = 360/464 (77%), Positives = 408/464 (87%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+VI SVEPR+A ATR+EL DQR SLKLIASENYASPAVLLTMGTW SDKYAEGT+GHRF
Sbjct: 18  LEVIASVEPRIAEATRQELVDQRGSLKLIASENYASPAVLLTMGTWLSDKYAEGTVGHRF 77

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHARELFGAPYAY QPHSGIDANLVAFW+ILA RVE P L   GA
Sbjct: 78  YAGCQNVDTVEALAAEHARELFGAPYAYAQPHSGIDANLVAFWSILAHRVETPALERLGA 137

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           K++N+L+EADWE+LR++LGNQRLLGM+LDAGGHLTHGFRPNISGKMFHQ+ YGT+PETG 
Sbjct: 138 KNVNELTEADWESLRHELGNQRLLGMALDAGGHLTHGFRPNISGKMFHQQQYGTDPETGL 197

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDY AVAA AREFKPLV+VAGYSAYPRRV+FAKMREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 198 LDYAAVAAKAREFKPLVIVAGYSAYPRRVDFAKMREIADEVGATLMVDMAHFAGLVAGKV 257

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDP+PHAH+     HKSLRGPRGG+VLA E++A  VD+GCPMVLGGPL HVM    
Sbjct: 258 FTGDEDPIPHAHITTTTTHKSLRGPRGGLVLAQEDFAADVDRGCPMVLGGPLGHVMAAKA 317

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+P F+ YAQ +ADNAQ+LA+GF+ R A LVTGGTDNH+VLLDV++FGLTGRQA
Sbjct: 318 VALAEARRPEFRTYAQNIADNAQSLAEGFLSRGARLVTGGTDNHLVLLDVSAFGLTGRQA 377

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLD+G+VTNRNSIP DPNGAWYTSG+RLGTPALT+RGFG D+FDRVAELIV+VL+NT
Sbjct: 378 ESALLDSGVVTNRNSIPQDPNGAWYTSGIRLGTPALTTRGFGHDEFDRVAELIVDVLSNT 437

Query: 452 QPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           +P  T     SKA Y+L DG A++VHAA++ELL  +PLYPGL L
Sbjct: 438 EPGTTKDGKPSKASYRLGDGVADKVHAAAAELLDKHPLYPGLDL 481


>tr|D2SAA3|D2SAA3_GEOOG Tax_Id=526225 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Geodermatophilus
           obscurus]
          Length = 490

 Score =  710 bits (1832), Expect = 0.0
 Identities = 349/464 (75%), Positives = 397/464 (85%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           LQVI +VEPRVA A   ELADQR SLKLIASENYASPAVLLTMG W SDKYAEGT+GHRF
Sbjct: 26  LQVIGAVEPRVADAIGAELADQRASLKLIASENYASPAVLLTMGNWLSDKYAEGTVGHRF 85

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHARELFGAP+AYVQPHSGIDANLVAFWA+LA+RVE+P L   G 
Sbjct: 86  YAGCQNVDTVEALAAEHARELFGAPHAYVQPHSGIDANLVAFWAVLASRVESPALEKAGV 145

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           +H+N+L+++DW  LR +LG+QR+LGMSLDAGGHLTHGFRPNISGKMF Q SYGT+PETG 
Sbjct: 146 RHVNELTDSDWAALRRQLGDQRMLGMSLDAGGHLTHGFRPNISGKMFEQSSYGTDPETGL 205

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYDAV A A+EF+PL+L+AGYSAYPRRV+FA+MREIADEVGATL+VDMAHFAGLVAGKV
Sbjct: 206 LDYDAVRARAQEFRPLILMAGYSAYPRRVDFARMREIADEVGATLVVDMAHFAGLVAGKV 265

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGD DPVPHAHV     HKSLRGPRGGMVLA  EYA AVD+GCPMVLGGPL HVM    
Sbjct: 266 FTGDFDPVPHAHVVTTTTHKSLRGPRGGMVLAQPEYADAVDRGCPMVLGGPLPHVMAAKA 325

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+PAF  YAQ+V DNA +LA+G  +R A LVTGGTDNH+VL+DV+ FGLTGRQA
Sbjct: 326 VAFAEARRPAFAGYAQRVVDNAVSLAEGLTRRGARLVTGGTDNHLVLVDVSGFGLTGRQA 385

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLDAGIVTNRN++PADPNGAWYTSG+RLGTPAL++RGFGAD+FDR AELIV+VL+NT
Sbjct: 386 ESALLDAGIVTNRNAVPADPNGAWYTSGIRLGTPALSTRGFGADEFDRTAELIVDVLSNT 445

Query: 452 QPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            P  T     SKA+Y  ADG A+R  AA++E+L  +PLYPGL L
Sbjct: 446 TPTATRDGSPSKARYATADGLADRTRAAAAEMLDRHPLYPGLDL 489


>tr|D2PKS4|D2PKS4_KRIFD Tax_Id=479435 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Kribbella flavida]
          Length = 482

 Score =  704 bits (1817), Expect = 0.0
 Identities = 347/464 (74%), Positives = 389/464 (83%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+VI +VEP +A A R EL DQR SLKLIASENYASPA LLTMG W SDKYAEGT+GHRF
Sbjct: 18  LEVIGAVEPTIAGAIRAELDDQRSSLKLIASENYASPATLLTMGNWLSDKYAEGTVGHRF 77

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE  AA+HA+ LF AP+AYVQPHSGIDANLVAFWAILA R+E+P LA   A
Sbjct: 78  YAGCQNVDTVEQAAADHAKALFDAPHAYVQPHSGIDANLVAFWAILANRIESPALAQASA 137

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           KH+NDLS+ DW TLR  LG+Q++LGMSLDAGGHLTHGFRPNISGKMFHQ SYGT+PETG 
Sbjct: 138 KHVNDLSDEDWTTLRKALGDQKMLGMSLDAGGHLTHGFRPNISGKMFHQSSYGTDPETGL 197

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD VAA AREFKPL+L+AGYSAYPR+++FAKMREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 198 LDYDKVAATAREFKPLILIAGYSAYPRKIDFAKMREIADEVGATLMVDMAHFAGLVAGKV 257

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGD DPVPHAHV     HKSLRGPRGGMVL   EYA AVD+GCPMVLGGPLS VM    
Sbjct: 258 FTGDFDPVPHAHVTTTTTHKSLRGPRGGMVLCQPEYADAVDRGCPMVLGGPLSQVMAAKA 317

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+P FQ YAQ VADNA ALA+G +KR   LVT GT+NH+VLLDV+S+G+TGRQA
Sbjct: 318 VALAEARRPEFQTYAQAVADNAVALAEGLMKRGVKLVTDGTENHLVLLDVSSYGITGRQA 377

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ESALLDAGIVTNRN++P DPNGAWYTSGVR+GTPALT+RGFG D+FDRVAEL+V+VL++ 
Sbjct: 378 ESALLDAGIVTNRNAVPRDPNGAWYTSGVRIGTPALTTRGFGVDEFDRVAELMVDVLSSV 437

Query: 452 QPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            P  T     SKAKY LADG A++  AAS+ELL  +PLYPGL L
Sbjct: 438 TPTTTSAGAASKAKYVLADGVADKTRAASAELLDKHPLYPGLDL 481


>sp|Q6AAU3|GLYA_PROAC Tax_Id=1747 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Propionibacterium acnes]
          Length = 491

 Score =  678 bits (1750), Expect = 0.0
 Identities = 339/465 (72%), Positives = 380/465 (81%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L  I  VEPR+A ATR EL DQR SLKLIASENYAS  VL TMGTWFSDKYAEGT GHRF
Sbjct: 26  LDAIAQVEPRIAEATRAELTDQRHSLKLIASENYASLPVLATMGTWFSDKYAEGTAGHRF 85

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHA  LFGA +AYVQPHSGIDANL A+W ILA  +E P L+ FGA
Sbjct: 86  YAGCQNVDTVETIAAEHACALFGAEHAYVQPHSGIDANLTAYWTILAHHIETPALSEFGA 145

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL++ DW+TLR++  +QR +GMSLDAGGHLTHGFRPNISGKMF QRSYGT+P+TG 
Sbjct: 146 RTVNDLTQVDWDTLRHRFNDQRAIGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPQTGL 205

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD VA  AREFKPLV+VAGYSAYPRRVNFAKMREIADEVGA LMVDMAHFAGLVAGKV
Sbjct: 206 LDYDKVAELAREFKPLVIVAGYSAYPRRVNFAKMREIADEVGAVLMVDMAHFAGLVAGKV 265

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDE+P+PHA V     HKSLRGPRGGMVL T++YA  VD+GCPMVLGGPLSHVM    
Sbjct: 266 FTGDENPIPHAQVVTTTTHKSLRGPRGGMVLTTKDYADDVDRGCPMVLGGPLSHVMAAKA 325

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R   F+ YAQ+VA+NA+ALA+G +KR   LVT GTDNHI LLDV TSFGLTGRQ
Sbjct: 326 VALAEARTQTFRDYAQRVANNAKALAEGLMKRGVKLVTDGTDNHINLLDVTTSFGLTGRQ 385

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLDAG+VTNRNSIP DPNGAWYTSG+R+GTPALTSRGFG D+FD+VAELIV  L  
Sbjct: 386 AEAALLDAGVVTNRNSIPTDPNGAWYTSGIRIGTPALTSRGFGPDEFDQVAELIVTTLEA 445

Query: 451 TQPEGTS-----KAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T P   S     KAKY++ADG A++VH A+ ELL   PLYPGL L
Sbjct: 446 TTPMTASTGKPGKAKYQIADGVAQKVHDAADELLGNFPLYPGLDL 490


>tr|D4HB50|D4HB50_PROAS Tax_Id=553199 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Propionibacterium
           acnes]
          Length = 491

 Score =  678 bits (1750), Expect = 0.0
 Identities = 339/465 (72%), Positives = 380/465 (81%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L  I  VEPR+A ATR EL DQR SLKLIASENYAS  VL TMGTWFSDKYAEGT GHRF
Sbjct: 26  LDAIAQVEPRIAEATRAELTDQRHSLKLIASENYASLPVLATMGTWFSDKYAEGTAGHRF 85

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHA  LFGA +AYVQPHSGIDANL A+W ILA  +E P L+ FGA
Sbjct: 86  YAGCQNVDTVETIAAEHACALFGAEHAYVQPHSGIDANLTAYWTILAHHIETPALSEFGA 145

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL++ DW+TLR++  +QR +GMSLDAGGHLTHGFRPNISGKMF QRSYGT+P+TG 
Sbjct: 146 RTVNDLTQVDWDTLRHRFNDQRAIGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPQTGL 205

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD VA  AREFKPLV+VAGYSAYPRRVNFAKMREIADEVGA LMVDMAHFAGLVAGKV
Sbjct: 206 LDYDKVAELAREFKPLVIVAGYSAYPRRVNFAKMREIADEVGAVLMVDMAHFAGLVAGKV 265

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDE+P+PHA V     HKSLRGPRGGMVL T++YA  VD+GCPMVLGGPLSHVM    
Sbjct: 266 FTGDENPIPHAQVVTTTTHKSLRGPRGGMVLTTKDYADDVDRGCPMVLGGPLSHVMAAKA 325

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R   F+ YAQ+VA+NA+ALA+G +KR   LVT GTDNHI LLDV TSFGLTGRQ
Sbjct: 326 VALAEARTQTFRDYAQRVANNAKALAEGLMKRGVKLVTDGTDNHINLLDVTTSFGLTGRQ 385

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLDAG+VTNRNSIP DPNGAWYTSG+R+GTPALTSRGFG D+FD+VAELIV  L  
Sbjct: 386 AEAALLDAGVVTNRNSIPTDPNGAWYTSGIRIGTPALTSRGFGPDEFDQVAELIVTTLEA 445

Query: 451 TQPEGTS-----KAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T P   S     KAKY++ADG A++VH A+ ELL   PLYPGL L
Sbjct: 446 TTPMTASTGKPGKAKYQIADGVAQKVHDAADELLGNFPLYPGLDL 490


>tr|D3MHV2|D3MHV2_PROAC Tax_Id=686659 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Propionibacterium
           acnes SK187]
          Length = 491

 Score =  678 bits (1750), Expect = 0.0
 Identities = 339/465 (72%), Positives = 380/465 (81%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L  I  VEPR+A ATR EL DQR SLKLIASENYAS  VL TMGTWFSDKYAEGT GHRF
Sbjct: 26  LDAIAQVEPRIAEATRAELTDQRHSLKLIASENYASLPVLATMGTWFSDKYAEGTAGHRF 85

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHA  LFGA +AYVQPHSGIDANL A+W ILA  +E P L+ FGA
Sbjct: 86  YAGCQNVDTVETIAAEHACALFGAEHAYVQPHSGIDANLTAYWTILAHHIETPALSEFGA 145

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL++ DW+TLR++  +QR +GMSLDAGGHLTHGFRPNISGKMF QRSYGT+P+TG 
Sbjct: 146 RTVNDLTQVDWDTLRHRFNDQRAIGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPQTGL 205

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD VA  AREFKPLV+VAGYSAYPRRVNFAKMREIADEVGA LMVDMAHFAGLVAGKV
Sbjct: 206 LDYDKVAELAREFKPLVIVAGYSAYPRRVNFAKMREIADEVGAVLMVDMAHFAGLVAGKV 265

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDE+P+PHA V     HKSLRGPRGGMVL T++YA  VD+GCPMVLGGPLSHVM    
Sbjct: 266 FTGDENPIPHAQVVTTTTHKSLRGPRGGMVLTTKDYADDVDRGCPMVLGGPLSHVMAAKA 325

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R   F+ YAQ+VA+NA+ALA+G +KR   LVT GTDNHI LLDV TSFGLTGRQ
Sbjct: 326 VALAEARTQTFRDYAQRVANNAKALAEGLMKRGVKLVTDGTDNHINLLDVTTSFGLTGRQ 385

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLDAG+VTNRNSIP DPNGAWYTSG+R+GTPALTSRGFG D+FD+VAELIV  L  
Sbjct: 386 AEAALLDAGVVTNRNSIPTDPNGAWYTSGIRIGTPALTSRGFGPDEFDQVAELIVTTLEA 445

Query: 451 TQPEGTS-----KAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T P   S     KAKY++ADG A++VH A+ ELL   PLYPGL L
Sbjct: 446 TTPMTASTGKPGKAKYQIADGVAQKVHDAADELLGNFPLYPGLDL 490


>tr|D3MHI1|D3MHI1_PROAC Tax_Id=679195 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Propionibacterium
           acnes J165]
          Length = 491

 Score =  678 bits (1750), Expect = 0.0
 Identities = 339/465 (72%), Positives = 380/465 (81%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L  I  VEPR+A ATR EL DQR SLKLIASENYAS  VL TMGTWFSDKYAEGT GHRF
Sbjct: 26  LDAIAQVEPRIAEATRAELTDQRHSLKLIASENYASLPVLATMGTWFSDKYAEGTAGHRF 85

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHA  LFGA +AYVQPHSGIDANL A+W ILA  +E P L+ FGA
Sbjct: 86  YAGCQNVDTVETIAAEHACALFGAEHAYVQPHSGIDANLTAYWTILAHHIETPALSEFGA 145

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL++ DW+TLR++  +QR +GMSLDAGGHLTHGFRPNISGKMF QRSYGT+P+TG 
Sbjct: 146 RTVNDLTQVDWDTLRHRFNDQRAIGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPQTGL 205

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD VA  AREFKPLV+VAGYSAYPRRVNFAKMREIADEVGA LMVDMAHFAGLVAGKV
Sbjct: 206 LDYDKVAELAREFKPLVIVAGYSAYPRRVNFAKMREIADEVGAVLMVDMAHFAGLVAGKV 265

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDE+P+PHA V     HKSLRGPRGGMVL T++YA  VD+GCPMVLGGPLSHVM    
Sbjct: 266 FTGDENPIPHAQVVTTTTHKSLRGPRGGMVLTTKDYADDVDRGCPMVLGGPLSHVMAAKA 325

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R   F+ YAQ+VA+NA+ALA+G +KR   LVT GTDNHI LLDV TSFGLTGRQ
Sbjct: 326 VALAEARTQTFRDYAQRVANNAKALAEGLMKRGVKLVTDGTDNHINLLDVTTSFGLTGRQ 385

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLDAG+VTNRNSIP DPNGAWYTSG+R+GTPALTSRGFG D+FD+VAELIV  L  
Sbjct: 386 AEAALLDAGVVTNRNSIPTDPNGAWYTSGIRIGTPALTSRGFGPDEFDQVAELIVTTLEA 445

Query: 451 TQPEGTS-----KAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T P   S     KAKY++ADG A++VH A+ ELL   PLYPGL L
Sbjct: 446 TTPMTASTGKPGKAKYQIADGVAQKVHDAADELLGNFPLYPGLDL 490


>tr|D1YAB0|D1YAB0_PROAC Tax_Id=679194 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Propionibacterium
           acnes J139]
          Length = 489

 Score =  673 bits (1737), Expect = 0.0
 Identities = 336/465 (72%), Positives = 378/465 (81%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L  I  VEPR+A ATR EL DQR SLKLIASENYAS  VL TMGTW SDKYAEGT GHRF
Sbjct: 24  LDAIAQVEPRIAEATRAELTDQRHSLKLIASENYASLPVLATMGTWLSDKYAEGTAGHRF 83

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVD+VE++AAEHA  LFGA +AYVQPHSGIDANL A+WAIL   +E P LA F A
Sbjct: 84  YAGCQNVDSVETIAAEHACALFGADHAYVQPHSGIDANLTAYWAILTHHIETPALAEFSA 143

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL++ DW+TLR++  +QR +GMSLD GGHLTHGFRPNISGKMF QRSYGT+P+TG 
Sbjct: 144 RTVNDLTQEDWDTLRHRFNDQRAIGMSLDTGGHLTHGFRPNISGKMFDQRSYGTDPQTGL 203

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD VA  AREFKPLV+VAGYSAYPRRVNFAKMREIADEVGA LMVDMAHFAGLVAGKV
Sbjct: 204 LDYDKVAELAREFKPLVIVAGYSAYPRRVNFAKMREIADEVGAVLMVDMAHFAGLVAGKV 263

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPVPHA +     HKSLRGPRGGMVL T++YA  VD+GCPMVLGGPLSHVM    
Sbjct: 264 FTGDEDPVPHAQIVTTTTHKSLRGPRGGMVLTTKDYADDVDRGCPMVLGGPLSHVMAAKA 323

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R  AF+ YA++VADN++ALA+G +KR   L+T GTDNHI LLDV TSFGL GRQ
Sbjct: 324 VALAEARTQAFRDYARRVADNSKALAEGLMKRGVKLITNGTDNHINLLDVTTSFGLAGRQ 383

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLDAG+VTNRNSIPADPNGAWYTSG+R+GTPALTSRGFG+D+FD+VAELIV  L  
Sbjct: 384 AEAALLDAGVVTNRNSIPADPNGAWYTSGIRIGTPALTSRGFGSDEFDQVAELIVTTLKA 443

Query: 451 TQPEGTS-----KAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T P  +S     KAKY + DG A+RVH A+ ELL   PLYPGL L
Sbjct: 444 TTPLTSSTGKPGKAKYHITDGVAQRVHDAADELLGNFPLYPGLDL 488


>sp|A8M1D3|GLYA_SALAI Tax_Id=391037 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Salinispora arenicola]
          Length = 478

 Score =  664 bits (1713), Expect = 0.0
 Identities = 330/464 (71%), Positives = 376/464 (81%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+VI +VEPRVA A R EL DQR+SLKLIASENYASPA LL MG WFSDKYAEGTIG RF
Sbjct: 14  LEVISAVEPRVADAIRSELTDQRESLKLIASENYASPATLLAMGNWFSDKYAEGTIGRRF 73

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDT+E++AAEHARELFGA +AYVQPHSGIDANLVAFWA+LA RVE+P L    A
Sbjct: 74  YAGCQNVDTIEALAAEHARELFGATHAYVQPHSGIDANLVAFWAVLADRVESPTLERARA 133

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           +H+NDL+EADW  LR +LGNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+PETG 
Sbjct: 134 RHVNDLTEADWFALRRELGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPETGL 193

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYD VA AAREF+PL+LVAGYSAYPR+VNF  MREIAD VGAT MVDMAHFAGLVAGKV
Sbjct: 194 IDYDQVAEAAREFRPLILVAGYSAYPRKVNFRIMREIADSVGATFMVDMAHFAGLVAGKV 253

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGD DPVPHAH+     HKSLRGPRGG+VL   E A  VD+GCPMVLGGPL HVM    
Sbjct: 254 FTGDFDPVPHAHIVTSTTHKSLRGPRGGLVLCGPELAEQVDRGCPMVLGGPLPHVMAAKA 313

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+P F  YA+++  NAQALADG ++R A LVTGGTDNH+ L+DVT +GLTGRQA
Sbjct: 314 VALAEARRPDFADYAERIVANAQALADGLLRRGAKLVTGGTDNHLALIDVTGYGLTGRQA 373

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E ALLD+GIVTNRN++P DPNGAWYTSG+R+GTPALT+RG G  + +  AELI  VL+ T
Sbjct: 374 EQALLDSGIVTNRNAVPQDPNGAWYTSGIRVGTPALTTRGLGTAELEATAELIHTVLSLT 433

Query: 452 QP----EGT-SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            P    +GT SKAKY L    A+RV+  +SELL+  PLYP + L
Sbjct: 434 SPGANADGTPSKAKYVLDPAVADRVNKQASELLAGFPLYPAIDL 477


>tr|D1S2F3|D1S2F3_9ACTO Tax_Id=644283 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Micromonospora
           aurantiaca ATCC 27029]
          Length = 478

 Score =  662 bits (1708), Expect = 0.0
 Identities = 333/465 (71%), Positives = 373/465 (80%), Gaps = 7/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+V+  VEPRVA A   ELADQR+SLKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 14  LEVVRGVEPRVADAIAAELADQRESLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 73

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHARELFGA +AYVQPHSGIDANLVAFWAILA RVE+P L    A
Sbjct: 74  YAGCQNVDTVEALAAEHARELFGASHAYVQPHSGIDANLVAFWAILADRVESPALRKAQA 133

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL+EADW  LR +LGNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 134 RQVNDLTEADWFALRRELGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 193

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYD VA AAREFKPL+LVAGYSAYPR+VNF  MREIAD VGAT MVDMAHFAGLVAGKV
Sbjct: 194 IDYDRVAEAAREFKPLILVAGYSAYPRKVNFRIMREIADSVGATFMVDMAHFAGLVAGKV 253

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGD DPVPHAH+     HKSLRGPRGGMVL   E A  VD+GCPMVLGGPL HVM    
Sbjct: 254 FTGDFDPVPHAHIVTTTTHKSLRGPRGGMVLCGPELADQVDRGCPMVLGGPLPHVMAAKA 313

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+P F  YAQ++ DNAQALADG ++R A LVTGGTDNH+VL+DV+ +GLTGRQA
Sbjct: 314 VALAEARRPDFADYAQRIVDNAQALADGLLRRGATLVTGGTDNHLVLIDVSGYGLTGRQA 373

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E ALLD+GIVTNRNS+P DPNGAWYTSG+R+GTPALT+RG GA + D  AELI  VL+ T
Sbjct: 374 EQALLDSGIVTNRNSVPQDPNGAWYTSGIRIGTPALTTRGLGAAEMDATAELIHTVLSQT 433

Query: 452 QPEGT------SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            P GT      SKAKY L    AE V   +++LL+  PLYP + L
Sbjct: 434 TP-GTGPDGAPSKAKYVLDPAVAESVGKQAADLLTPFPLYPAVDL 477


>tr|D3CEU5|D3CEU5_9ACTO Tax_Id=648999 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Micromonospora sp.
           L5]
          Length = 478

 Score =  662 bits (1707), Expect = 0.0
 Identities = 333/465 (71%), Positives = 373/465 (80%), Gaps = 7/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+V+  VEPRVA A   ELADQR+SLKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 14  LEVVRGVEPRVADAIAAELADQRESLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 73

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHARELFGA +AYVQPHSGIDANLVAFWAILA RVE+P L    A
Sbjct: 74  YAGCQNVDTVEALAAEHARELFGASHAYVQPHSGIDANLVAFWAILADRVESPALRKAQA 133

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL+EADW  LR +LGNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 134 RQVNDLTEADWFALRRELGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 193

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYD VA AAREFKPL+LVAGYSAYPR+VNF  MREIAD VGAT MVDMAHFAGLVAGKV
Sbjct: 194 IDYDRVAEAAREFKPLILVAGYSAYPRKVNFRIMREIADSVGATFMVDMAHFAGLVAGKV 253

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGD DPVPHAH+     HKSLRGPRGGMVL   E A  VD+GCPMVLGGPL HVM    
Sbjct: 254 FTGDFDPVPHAHIVTTTTHKSLRGPRGGMVLCGPELADHVDRGCPMVLGGPLPHVMAAKA 313

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+P F  YAQ++ DNAQALADG ++R A LVTGGTDNH+VL+DV+ +GLTGRQA
Sbjct: 314 VALAEARRPDFADYAQRIVDNAQALADGLLRRGATLVTGGTDNHLVLIDVSGYGLTGRQA 373

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E ALLD+GIVTNRNS+P DPNGAWYTSG+R+GTPALT+RG GA + D  AELI  VL+ T
Sbjct: 374 EQALLDSGIVTNRNSVPQDPNGAWYTSGIRIGTPALTTRGLGAAEMDATAELIHTVLSQT 433

Query: 452 QPEGT------SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            P GT      SKAKY L    AE V   +++LL+  PLYP + L
Sbjct: 434 TP-GTGPDGAPSKAKYVLDPAVAESVGKQAADLLTPFPLYPAVDL 477


>sp|A4X6P4|GLYA_SALTO Tax_Id=369723 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Salinispora tropica]
          Length = 478

 Score =  658 bits (1697), Expect = 0.0
 Identities = 328/464 (70%), Positives = 372/464 (80%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+VI +VEPRVA A R EL DQR+SLKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 14  LEVIGAVEPRVANAIRAELTDQRESLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 73

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHARELFGAPYAYVQPHSGIDANLVAFWA+LA R+E+P L    A
Sbjct: 74  YAGCQNVDTVEALAAEHARELFGAPYAYVQPHSGIDANLVAFWAVLADRIESPALRRAQA 133

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           +H+NDL+EADW  LR +LGNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+PETG 
Sbjct: 134 RHVNDLTEADWFALRRELGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPETGL 193

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYD VA AAREFKPL+L+ GYSAYPR+VNF  +REIAD VGAT MVDMAHFAGLVAGK 
Sbjct: 194 IDYDGVAEAAREFKPLILLGGYSAYPRKVNFRILREIADSVGATFMVDMAHFAGLVAGKA 253

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGD DPVPHAH+     HKSLRGPRGG+VL   E A  VD+GCPMVLGGPL  VM    
Sbjct: 254 FTGDFDPVPHAHIVTSTTHKSLRGPRGGLVLCGPELAEQVDRGCPMVLGGPLPQVMAAKA 313

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+P F  YA ++  NAQALADG  +R A LVTGGTDNH+ L+DVT +GLTGRQA
Sbjct: 314 VALAEARRPDFVDYAGRIVANAQALADGLQRRGAQLVTGGTDNHLALIDVTGYGLTGRQA 373

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E ALLD+GIVTNRN+IP DPNGAWYTSG+R+GTPALT+RG G  + D  AELI  VL++T
Sbjct: 374 EHALLDSGIVTNRNAIPQDPNGAWYTSGIRVGTPALTTRGLGTAELDATAELIHTVLSHT 433

Query: 452 QP----EGT-SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            P    +GT SKAKY L    A+RV   +S+LL+  PLYP + L
Sbjct: 434 APGTNADGTSSKAKYVLDPAVADRVGKQASDLLTGFPLYPAIDL 477


>tr|C4RDT9|C4RDT9_9ACTO Tax_Id=219305 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Micromonospora sp.
           ATCC 39149]
          Length = 479

 Score =  652 bits (1683), Expect = 0.0
 Identities = 323/464 (69%), Positives = 375/464 (80%), Gaps = 5/464 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+VI +VEPR+A A   ELADQR+SLKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 15  LEVIRAVEPRIADAIGAELADQRESLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 74

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGCQNVDTVE++AAEHA+ELFGA +AYVQPHSGIDANLVAFWAILA RVE+P L     
Sbjct: 75  YAGCQNVDTVEALAAEHAKELFGAAHAYVQPHSGIDANLVAFWAILADRVESPALRRAQV 134

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL+E DW  LR +LG+QR+LGMSLD+GGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 135 RQVNDLTEQDWFALRRELGDQRMLGMSLDSGGHLTHGFRPNISGKMFDQRSYGTDPATGL 194

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYD VA AAREF+PL+LVAGYSAYPR+VNF  MREIAD VGAT MVDMAHFAGLVAGKV
Sbjct: 195 IDYDRVAEAAREFRPLILVAGYSAYPRKVNFRIMREIADSVGATFMVDMAHFAGLVAGKV 254

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGD DPVPHAH+     HKSLRGPRGGMVL   E A  VD+GCPMVLGGPL HVM    
Sbjct: 255 FTGDFDPVPHAHIVTTTTHKSLRGPRGGMVLCGPELADQVDRGCPMVLGGPLPHVMAAKA 314

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R+P F  YA+++ DNAQALA+G ++R A LVTGGTDNH+VL+DV+ +GLTGRQA
Sbjct: 315 VALAEARRPDFADYARRIVDNAQALAEGLLRRGAKLVTGGTDNHLVLIDVSGYGLTGRQA 374

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E ALLD+GIVTNRN++P DPNGAWYTSG+R+GTPALT+RG G  + D  AELI  VL+ T
Sbjct: 375 EQALLDSGIVTNRNAVPQDPNGAWYTSGIRVGTPALTTRGLGTAEMDATAELIHTVLSQT 434

Query: 452 QP----EGT-SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            P    +GT SKAKY L    A++V   +++LL+ +PLYP +TL
Sbjct: 435 TPGSNADGTPSKAKYVLDPALADKVARQATDLLATHPLYPSVTL 478


>tr|D6KC91|D6KC91_9ACTO Tax_Id=645465 SubName: Full=Serine
           hydroxymethyltransferase;[Streptomyces sp. e14]
          Length = 481

 Score =  642 bits (1657), Expect = 0.0
 Identities = 323/465 (69%), Positives = 372/465 (80%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L VI +VEPRVA A  +E+ADQR+ LKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 16  LDVIRAVEPRVADAIGQEVADQREMLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 75

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVDTVES+AAEHA+ELFGA +AYVQPHSGIDANLVAFWA+LA RVEAP L   G 
Sbjct: 76  YAGCRNVDTVESLAAEHAKELFGARHAYVQPHSGIDANLVAFWAVLADRVEAPFLRKTGV 135

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + INDLSEADW  LR+  GNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 136 RQINDLSEADWAELRHAFGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 195

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYDA+ A AREFKPL+LVAGYSAYPR VNF  MREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 196 IDYDALRAQAREFKPLILVAGYSAYPRLVNFRIMREIADEVGATLMVDMAHFAGLVAGKV 255

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
            TGD DPVPHA +     HKSLRGPRGGMVL  +     VD+GCPMVLGGPL HVM    
Sbjct: 256 LTGDFDPVPHAQIVTTTTHKSLRGPRGGMVLCDDSLKDQVDRGCPMVLGGPLPHVMAAKA 315

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 RQPAFQ YA+++ DN++ALA+G  +R A LVTGGTDNH+ L+DV +S+GLTGRQ
Sbjct: 316 VALAEARQPAFQDYARRIVDNSRALAEGLTRRGATLVTGGTDNHLNLIDVASSYGLTGRQ 375

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLD+GIVTNRN+IPADPNGAWYTSG+R+GTPALT+RG G  + D VA LI  VL  
Sbjct: 376 AEAALLDSGIVTNRNAIPADPNGAWYTSGIRVGTPALTTRGLGTAEMDEVAGLIDRVLTT 435

Query: 451 TQPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T+P  T     SKA++ L    A+ +   +++L++A PLYP + L
Sbjct: 436 TEPGTTGKGAPSKAQHVLDPKIADEISQRATDLVAAFPLYPEIDL 480


>tr|C9YTF8|C9YTF8_STRSW Tax_Id=680198 (glyA1)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Streptomyces
           scabies]
          Length = 482

 Score =  641 bits (1653), Expect = 0.0
 Identities = 320/465 (68%), Positives = 371/465 (79%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L VI +VEPRVA A  +E+ DQR+ LKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 17  LDVIRAVEPRVADAIGQEVGDQREMLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 76

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVDTVES+AAEHARELFGA +AYVQPHSGIDANLVAFWA+LA RVEAP L   GA
Sbjct: 77  YAGCRNVDTVESLAAEHARELFGARHAYVQPHSGIDANLVAFWAVLADRVEAPFLEKTGA 136

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDLSEADW  LR   GNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 137 RQVNDLSEADWAELRQAFGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 196

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DY+A+ A+AR+FKP+++VAGYSAYPR VNF  MREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 197 IDYEALRASARDFKPMIIVAGYSAYPRLVNFRIMREIADEVGATLMVDMAHFAGLVAGKV 256

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
            TGD DPVPHA +     HKSLRGPRGGMVL  +     VD+GCPMVLGGPL HVM    
Sbjct: 257 LTGDFDPVPHAQIVTTTTHKSLRGPRGGMVLCDDSLKDQVDRGCPMVLGGPLPHVMAAKA 316

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R+PAFQ YAQ++ DNA+ALA+G  +R A LVTGGTDNH+ L+DV TS+GLTGRQ
Sbjct: 317 VALAEARRPAFQDYAQRIVDNARALAEGLTRRGATLVTGGTDNHLNLIDVTTSYGLTGRQ 376

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLD+GIVTNRN+IPADPNGAWYTSG+R+GTPALT+RG G  + D VA LI  VL  
Sbjct: 377 AEAALLDSGIVTNRNAIPADPNGAWYTSGIRIGTPALTTRGLGTAEMDEVAGLIDRVLTT 436

Query: 451 TQPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T+P  T     SKA++ L    A+ +   +++L++  PLYP + L
Sbjct: 437 TEPGTTKSGAPSKAQHVLDAKVADEISRRATDLVAGFPLYPEIDL 481


>tr|Q9KZA9|Q9KZA9_STRCO Tax_Id=1902 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Streptomyces
           coelicolor]
          Length = 481

 Score =  638 bits (1645), Expect = 0.0
 Identities = 320/465 (68%), Positives = 369/465 (79%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L VI +VEPRVA A  +E+ADQR+ LKLIASENYASPA LL MG WFSDKYAEGTIG RF
Sbjct: 16  LDVIRAVEPRVADAIGQEVADQREMLKLIASENYASPATLLAMGNWFSDKYAEGTIGRRF 75

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVDTVES+AAEHARELFGA +AYVQPHSGIDANLVAFWA+L  RVE P L   GA
Sbjct: 76  YAGCRNVDTVESLAAEHARELFGARHAYVQPHSGIDANLVAFWAVLGARVEVPFLEKTGA 135

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL++ADW  LR   GNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 136 RQVNDLTDADWAELRQAFGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 195

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DY+A+ A+AREFKPL++VAGYSAYPR VNF  MREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 196 IDYEALRASAREFKPLIIVAGYSAYPRLVNFRIMREIADEVGATLMVDMAHFAGLVAGKV 255

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
            TGD DPVPHA +     HKSLRGPRGGMVL  +     VD+GCPMVLGGPL HVM    
Sbjct: 256 LTGDFDPVPHAQIVTTTTHKSLRGPRGGMVLCDDSLKDQVDRGCPMVLGGPLPHVMAAKA 315

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R+PAFQ YAQ++ DNA+ALA+G  KR A LVTGGTDNH+ L+DV +S+GLTGRQ
Sbjct: 316 VALAEARRPAFQDYAQRIVDNARALAEGLTKRGATLVTGGTDNHLNLIDVASSYGLTGRQ 375

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLD+GIVTNRN+IPADPNGAWYTSG+R+GTPALT+RG G  + D VA LI  VL  
Sbjct: 376 AEAALLDSGIVTNRNAIPADPNGAWYTSGIRIGTPALTTRGLGTAEMDEVAGLIDRVLTA 435

Query: 451 TQPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T+P  T     SKA + L    A+ +   +++L++  PLYP + L
Sbjct: 436 TEPGTTKSGAPSKASHVLDAKVADEISHRATDLVAGFPLYPEIDL 480


>tr|D6ECN5|D6ECN5_STRLI Tax_Id=457428 SubName: Full=Serine
           hydroxymethyltransferase;[Streptomyces lividans TK24]
          Length = 481

 Score =  638 bits (1645), Expect = 0.0
 Identities = 320/465 (68%), Positives = 369/465 (79%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L VI +VEPRVA A  +E+ADQR+ LKLIASENYASPA LL MG WFSDKYAEGTIG RF
Sbjct: 16  LDVIRAVEPRVADAIGQEVADQREMLKLIASENYASPATLLAMGNWFSDKYAEGTIGRRF 75

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVDTVES+AAEHARELFGA +AYVQPHSGIDANLVAFWA+L  RVE P L   GA
Sbjct: 76  YAGCRNVDTVESLAAEHARELFGARHAYVQPHSGIDANLVAFWAVLGARVEVPFLEKTGA 135

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDL++ADW  LR   GNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 136 RQVNDLTDADWAELRQAFGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 195

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DY+A+ A+AREFKPL++VAGYSAYPR VNF  MREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 196 IDYEALRASAREFKPLIIVAGYSAYPRLVNFRIMREIADEVGATLMVDMAHFAGLVAGKV 255

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
            TGD DPVPHA +     HKSLRGPRGGMVL  +     VD+GCPMVLGGPL HVM    
Sbjct: 256 LTGDFDPVPHAQIVTTTTHKSLRGPRGGMVLCDDSLKDQVDRGCPMVLGGPLPHVMAAKA 315

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R+PAFQ YAQ++ DNA+ALA+G  KR A LVTGGTDNH+ L+DV +S+GLTGRQ
Sbjct: 316 VALAEARRPAFQDYAQRIVDNARALAEGLTKRGATLVTGGTDNHLNLIDVASSYGLTGRQ 375

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLD+GIVTNRN+IPADPNGAWYTSG+R+GTPALT+RG G  + D VA LI  VL  
Sbjct: 376 AEAALLDSGIVTNRNAIPADPNGAWYTSGIRIGTPALTTRGLGTAEMDEVAGLIDRVLTA 435

Query: 451 TQPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T+P  T     SKA + L    A+ +   +++L++  PLYP + L
Sbjct: 436 TEPGTTKSGAPSKASHVLDAKVADEISHRATDLVAGFPLYPEIDL 480


>tr|Q82HT9|Q82HT9_STRAW Tax_Id=33903 (glyA3)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Streptomyces
           avermitilis]
          Length = 482

 Score =  636 bits (1640), Expect = e-180
 Identities = 317/465 (68%), Positives = 369/465 (79%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L VI +VEPRVA A  +E+ADQR+ LKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 17  LDVIRAVEPRVADAIGQEIADQREMLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 76

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVDTVE++AAEHARELFGA +AY QPHSGIDANLVAFWA+LA RVEAP LA  G 
Sbjct: 77  YAGCRNVDTVEALAAEHARELFGAQHAYAQPHSGIDANLVAFWAVLADRVEAPALAKAGV 136

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           +++NDLS+ADW  LR   GNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 137 RNVNDLSDADWAELRRAFGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 196

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DY+A+  +AREFKPL++VAGYSAYPR VNF  MREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 197 IDYEALRTSAREFKPLIIVAGYSAYPRLVNFRIMREIADEVGATLMVDMAHFAGLVAGKV 256

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
            TGD DPVPHA +     HKSLRGPRGGMVL  +     VD+GCPMVLGGPL HVM    
Sbjct: 257 LTGDFDPVPHAQIVTTTTHKSLRGPRGGMVLCDDSLKDQVDRGCPMVLGGPLPHVMAAKA 316

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 R+P F+ YAQ V DN++ALA+G V+R A LVTGGTDNH+ L+DV +S+GLTGRQ
Sbjct: 317 VALAEARRPEFRDYAQAVVDNSRALAEGLVRRGATLVTGGTDNHLNLIDVASSYGLTGRQ 376

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALLD+GIVTNRN+IPADPNGAWYTSG+R+GTPALT+RG G  + D +A LI  VL  
Sbjct: 377 AETALLDSGIVTNRNAIPADPNGAWYTSGIRIGTPALTTRGLGTAEMDEIAGLIDRVLTT 436

Query: 451 TQPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T+P  T     SKA++ L    A+ +   + +LL+  PLYP + L
Sbjct: 437 TEPGTTAKGAPSKAQHVLDPKIADEIAHRAGDLLTGFPLYPEIDL 481


>tr|B5HVC0|B5HVC0_9ACTO Tax_Id=463191 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Streptomyces
           sviceus ATCC 29083]
          Length = 483

 Score =  634 bits (1634), Expect = e-179
 Identities = 315/465 (67%), Positives = 369/465 (79%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L VI +VEPRVA A  +E+ DQR+ LKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 18  LDVIRAVEPRVADAIGQEVHDQREMLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 77

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVDTVES+AAEHA+ELFGA +AYVQPHSGIDANLVAFW++LA RVE P L   G 
Sbjct: 78  YAGCRNVDTVESLAAEHAKELFGARHAYVQPHSGIDANLVAFWSVLAQRVEVPALEKAGV 137

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + +NDLS+ADW  LR   GNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 138 RQVNDLSDADWAELRQAFGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 197

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYDA+  +AREFKPL++VAGYSAYPR VNF  MREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 198 VDYDALRVSAREFKPLIIVAGYSAYPRLVNFRIMREIADEVGATLMVDMAHFAGLVAGKV 257

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
            TGD DPVPHA +     HKSLRGPRGGMVL  +     VD+GCPMVLGGPL HVM    
Sbjct: 258 LTGDFDPVPHAQIVTTTTHKSLRGPRGGMVLCDDSLKDQVDRGCPMVLGGPLPHVMAAKA 317

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVT-SFGLTGRQ 390
                 RQP+FQ YAQ++ DN++ALA+G ++R A LVTGGTDNH+ L+DVT S+GLTGRQ
Sbjct: 318 VALAEARQPSFQDYAQRIVDNSRALAEGLMRRGATLVTGGTDNHLNLIDVTSSYGLTGRQ 377

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE+ALL++GIVTNRN+IPADPNGAWYTSG+R+GTPALT+RG G  + D VA LI  VL  
Sbjct: 378 AEAALLESGIVTNRNAIPADPNGAWYTSGIRIGTPALTTRGLGTAEMDEVAGLIDRVLTT 437

Query: 451 TQPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T+P  T     SKA++ L    A+ +   +++L++  PLYP + L
Sbjct: 438 TEPGTTSKGAPSKAQHILDPKVADEISHRATDLVAGFPLYPEIDL 482


>tr|D6A1Z6|D6A1Z6_9ACTO Tax_Id=566461 SubName: Full=Serine
           hydroxymethyltransferase;[Streptomyces ghanaensis ATCC
           14672]
          Length = 482

 Score =  631 bits (1627), Expect = e-179
 Identities = 317/465 (68%), Positives = 368/465 (79%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L VI +VEPRVA A  +E+ADQR+ LKLIASENYASPA LL MG WFSDKYAEGT+G RF
Sbjct: 17  LDVIRAVEPRVADAIGQEVADQREMLKLIASENYASPATLLAMGNWFSDKYAEGTVGRRF 76

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVDTVES+AAEHA+ELFGA +AYVQPHSGIDANLVAFWA+LA RVEAP L   G 
Sbjct: 77  YAGCRNVDTVESLAAEHAKELFGARHAYVQPHSGIDANLVAFWAVLADRVEAPFLEKTGV 136

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           + INDLS+ADW  LR   GNQR+LGMSLDAGGHLTHGFRPNISGKMF QRSYGT+P TG 
Sbjct: 137 RQINDLSDADWAELRQAFGNQRMLGMSLDAGGHLTHGFRPNISGKMFDQRSYGTDPATGL 196

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYDA+ A AREFKPL++VAGYSAYPR VNF  MREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 197 IDYDALRAQAREFKPLIIVAGYSAYPRLVNFRIMREIADEVGATLMVDMAHFAGLVAGKV 256

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
            TGD DPVPHA +     HKSLRGPRGGMVL  +     VD+GCPMVLGGPL HVM    
Sbjct: 257 LTGDFDPVPHAQIVTTTTHKSLRGPRGGMVLCDDSLKDQVDRGCPMVLGGPLPHVMAAKA 316

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDV-TSFGLTGRQ 390
                 RQ +F+ YA+++ DN++ALA+G + R A LVTGGTDNH+ L+DV TS+GLTGRQ
Sbjct: 317 VALAEARQESFRDYARRIVDNSRALAEGLMSRGATLVTGGTDNHLNLIDVTTSYGLTGRQ 376

Query: 391 AESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN 450
           AE ALL++GIVTNRN+IPADPNGAWYTSG+R+GTPALT+RG G  + D VA LI  VL  
Sbjct: 377 AEVALLESGIVTNRNAIPADPNGAWYTSGIRVGTPALTTRGLGTAEMDEVAGLIDRVLTT 436

Query: 451 TQPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           T+P  T     SKA++ L    A+ +   +++L++  PLYP + L
Sbjct: 437 TEPGTTSKGAPSKAQHILDPKIADEISRRATDLVAGFPLYPEIDL 481


>tr|B5GB19|B5GB19_9ACTO Tax_Id=465543 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Streptomyces sp.
           SPB74]
          Length = 507

 Score =  597 bits (1540), Expect = e-169
 Identities = 294/403 (72%), Positives = 331/403 (82%), Gaps = 1/403 (0%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L V+ SVEPR+AAA  +ELADQR+SLKLIASENYASPA LL MG W SDKYAEGT GHRF
Sbjct: 43  LDVVRSVEPRIAAAIGQELADQRESLKLIASENYASPATLLAMGNWMSDKYAEGTAGHRF 102

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVDTVE++AAEHAR LFGA +AYVQPHSGIDANLVAFW++LA RVE+P LA  G 
Sbjct: 103 YAGCRNVDTVETIAAEHARALFGADHAYVQPHSGIDANLVAFWSVLAQRVESPALAEAGV 162

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           +++NDL+E DW  LR  LG+QR+LGMSLDAGGHLTHGFRPN+SGK+F QRSYGT+P TG 
Sbjct: 163 RNVNDLTEEDWSVLRRALGDQRMLGMSLDAGGHLTHGFRPNLSGKLFAQRSYGTDPGTGL 222

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           +DYDAV AAAREF+PL+L+AGYSAYPR VNF  MREIADEVGATLMVDMAHFAGLVAGKV
Sbjct: 223 IDYDAVRAAAREFRPLILIAGYSAYPRLVNFRIMREIADEVGATLMVDMAHFAGLVAGKV 282

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
            TG+ DPVP+A +     HKSLRGPRGGMVL  E  A  VD+GCPMVLGGPL HVM    
Sbjct: 283 LTGEHDPVPYAQIVTTTTHKSLRGPRGGMVLCEESLAEYVDRGCPMVLGGPLPHVMAAKA 342

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 RQPAF+ YAQQV DNA+ALA+G  +R A LVTGGTDNH+VLLDV+ +GLTGRQA
Sbjct: 343 VALAEARQPAFRTYAQQVVDNARALAEGLTRRGAKLVTGGTDNHLVLLDVSGYGLTGRQA 402

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTP-ALTSRGFG 433
           ESALLD GIVTNRN++P D NGAWYTSGV    P   T RG G
Sbjct: 403 ESALLDFGIVTNRNAVPQDANGAWYTSGVPARHPRRFTMRGLG 445


>sp|O83349|GLYA_TREPA Tax_Id=160 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Treponema pallidum]
          Length = 574

 Score =  498 bits (1283), Expect = e-139
 Identities = 253/462 (54%), Positives = 316/462 (68%), Gaps = 5/462 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L ++    P++A+   +EL DQR  +KLIASENY+S AV   M    +DKYAEG   HR+
Sbjct: 29  LDLVAHQFPQIASDIVQELIDQRSYVKLIASENYSSLAVQAAMANLLTDKYAEGFPHHRY 88

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           Y GCQNVD++ES AA  A  LFGA +AYVQPHSG DANLVAFWAIL+ ++E P L++ G 
Sbjct: 89  YGGCQNVDSIESAAAAEACALFGAEHAYVQPHSGADANLVAFWAILSRQIEMPTLSSLGV 148

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
                LSE  WE LR K+GNQ+L+G+   +GGHLTHG+R N+SG+MF   SY  + +TG 
Sbjct: 149 TAATHLSEEQWEVLRQKMGNQKLMGLDYFSGGHLTHGYRQNVSGRMFRVVSYAVDRDTGL 208

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDY A+ A A+  +PL+L+AGYSAYPR +NF   REIAD+VGA LM DMAHFAGLVAG V
Sbjct: 209 LDYAAIEAQAKRERPLILLAGYSAYPRSINFRIFREIADKVGAVLMADMAHFAGLVAGGV 268

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPV  +H+     HK+LRGPRG  +L  +E+A AVDKGCP+VLGGPL HVM    
Sbjct: 269 FTGDEDPVRWSHIVTSTTHKTLRGPRGAFILCKKEFAEAVDKGCPLVLGGPLPHVMAAKA 328

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R  AF+ YA  V DNA+ALAD  +++   L TGGTDNH++LLDV  FGLTGRQA
Sbjct: 329 VAFREARNAAFKTYAHAVRDNARALADACIQQGMQLQTGGTDNHLLLLDVRPFGLTGRQA 388

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E AL+D G+  NRNS+P DPNGAW TSG+R+GTPA+TS G G ++  R+A LI  VL   
Sbjct: 389 ERALIDCGVTLNRNSLPFDPNGAWLTSGLRIGTPAVTSLGMGPEEMKRIARLIARVLGAA 448

Query: 452 QPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGL 488
            P  T     SK+  ++       V +   ELL+   LYP L
Sbjct: 449 TPVRTKTGALSKSAAEVPGEVRSSVCSEVRELLARFTLYPEL 490


>tr|B2S2S6|B2S2S6_TREPS Tax_Id=455434 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Treponema pallidum
           subsp. pallidum]
          Length = 574

 Score =  498 bits (1283), Expect = e-139
 Identities = 253/462 (54%), Positives = 316/462 (68%), Gaps = 5/462 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L ++    P++A+   +EL DQR  +KLIASENY+S AV   M    +DKYAEG   HR+
Sbjct: 29  LDLVAHQFPQIASDIVQELIDQRSYVKLIASENYSSLAVQAAMANLLTDKYAEGFPHHRY 88

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           Y GCQNVD++ES AA  A  LFGA +AYVQPHSG DANLVAFWAIL+ ++E P L++ G 
Sbjct: 89  YGGCQNVDSIESAAAAEACALFGAEHAYVQPHSGADANLVAFWAILSRQIEMPTLSSLGV 148

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
                LSE  WE LR K+GNQ+L+G+   +GGHLTHG+R N+SG+MF   SY  + +TG 
Sbjct: 149 TAATHLSEEQWEVLRQKMGNQKLMGLDYFSGGHLTHGYRQNVSGRMFRVVSYAVDRDTGL 208

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDY A+ A A+  +PL+L+AGYSAYPR +NF   REIAD+VGA LM DMAHFAGLVAG V
Sbjct: 209 LDYAAIEAQAKRERPLILLAGYSAYPRSINFRIFREIADKVGAVLMADMAHFAGLVAGGV 268

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGDEDPV  +H+     HK+LRGPRG  +L  +E+A AVDKGCP+VLGGPL HVM    
Sbjct: 269 FTGDEDPVRWSHIVTSTTHKTLRGPRGAFILCKKEFAEAVDKGCPLVLGGPLPHVMAAKA 328

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                 R  AF+ YA  V DNA+ALAD  +++   L TGGTDNH++LLDV  FGLTGRQA
Sbjct: 329 VAFREARNAAFKTYAHAVRDNARALADACIQQGMQLQTGGTDNHLLLLDVRPFGLTGRQA 388

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E AL+D G+  NRNS+P DPNGAW TSG+R+GTPA+TS G G ++  R+A LI  VL   
Sbjct: 389 ERALIDCGVTLNRNSLPFDPNGAWLTSGLRIGTPAVTSLGMGPEEMKRIARLIARVLGAA 448

Query: 452 QPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGL 488
            P  T     SK+  ++       V +   ELL+   LYP L
Sbjct: 449 TPVRTKTGALSKSAAEVPGEVRSSVCSEVRELLARFTLYPEL 490


>tr|Q6ME31|Q6ME31_PARUW Tax_Id=264201 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Protochlamydia
           amoebophila]
          Length = 491

 Score =  483 bits (1244), Expect = e-134
 Identities = 240/465 (51%), Positives = 323/465 (69%), Gaps = 6/465 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L  IE+V P ++++  +EL D+R  LKLIASEN++S AV L MG   +DKYAEG   HRF
Sbjct: 27  LDHIETVSPTISSSIIQELQDERSHLKLIASENFSSLAVQLAMGNLLTDKYAEGYAHHRF 86

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC N+D++E  A++   +LFG  +AYVQPHSG DANLVA WAIL  +++ PE+  FG 
Sbjct: 87  YAGCDNIDSIEETASQELIQLFGCEHAYVQPHSGADANLVALWAILIHKIQNPEIEKFGK 146

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           K +++L+  ++E +R  L NQ+L+GMSL++GGHLTHG+R NIS KM     Y  +P+T  
Sbjct: 147 KTLDELTPEEYEKIRQLLVNQKLMGMSLNSGGHLTHGYRHNISSKMMRSVLYDVDPKTEI 206

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDY  +A   ++ +P +L+AGYSA+PRR+NFAKMREIAD VGATLMVDMAHFAGLVAGKV
Sbjct: 207 LDYSVLAKQVQQERPTILIAGYSAHPRRLNFAKMREIADSVGATLMVDMAHFAGLVAGKV 266

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           F G+ DP+P+A +     HK+LRGPRGG VL  + ++ A++KGCP VLGGPL +VM    
Sbjct: 267 FQGEFDPIPYADIVTSTTHKTLRGPRGGFVLCKQSFSEAINKGCPSVLGGPLPNVMAAKA 326

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                     F+QY+Q++ DNAQ+LA+ F++ D  LVTGGT+NH+++LD++ FGLTGRQA
Sbjct: 327 VAFKEANSLNFKQYSQKIVDNAQSLANCFLQNDIRLVTGGTENHLMILDLSKFGLTGRQA 386

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E+AL +A I  NRN+IP D  G WYTSG+RLGT ALT+ G G D+ + +A +I  VL+N+
Sbjct: 387 ETALREAHITVNRNAIPNDLQGPWYTSGIRLGTAALTTLGMGKDEMNEIASVIFSVLSNS 446

Query: 452 QP-----EGTSKAKYKLADGT-AERVHAASSELLSANPLYPGLTL 490
           +P      G       + D T      A    LL   PLYP + +
Sbjct: 447 KPGIVQKTGQPSKASVITDSTIINEAKARVKNLLIHFPLYPEIEI 491


>tr|D1R7V4|D1R7V4_9CHLA Tax_Id=159254 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Parachlamydia
           acanthamoebae str. Hall's coccus]
          Length = 490

 Score =  482 bits (1241), Expect = e-134
 Identities = 241/469 (51%), Positives = 320/469 (68%), Gaps = 14/469 (2%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L  IES  P +A A  +EL DQR  LKLIASENY+S  V L MG   +DKYAEG   HRF
Sbjct: 26  LDQIESFAPLIAHAIEQELRDQRSHLKLIASENYSSLTVQLAMGNLLTDKYAEGYPHHRF 85

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC+NVD VE +A E  +++FGA +AYVQPHSG DANLVAFW+IL  +V+  E+   G 
Sbjct: 86  YAGCENVDLVEEMAQEELKQIFGAEHAYVQPHSGADANLVAFWSILVQKVQNKEIERLGK 145

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
           K +++L+  ++E +R  +  Q+L+GMSL++GGHLTHG+R NIS KM     Y  +P+T  
Sbjct: 146 KTLDELTPEEYEQVRKLMNQQKLMGMSLNSGGHLTHGYRHNISSKMMRSVFYDVDPKTEQ 205

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDY  +A  A + KP +L+AGYSAY RR+NFAKMREIAD VGA  MVDMAHF+GLVAGKV
Sbjct: 206 LDYHTLAKQALQEKPDILLAGYSAYSRRINFAKMREIADSVGAVFMVDMAHFSGLVAGKV 265

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           F  + +PVP+AH+     HK+LRGPRGG VL   E+A  ++KGCP+VLGGPL HV+    
Sbjct: 266 FQDEYNPVPYAHIVTSTTHKTLRGPRGGFVLCKAEFADTINKGCPLVLGGPLPHVIAAKA 325

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                   P FQ YAQ++  NA  LA+      A +V+GGT+NH++++D++SFGLTGR A
Sbjct: 326 IAFKEANSPNFQDYAQRIVKNANTLAEKLKSDGARIVSGGTENHLMIVDLSSFGLTGRHA 385

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           ES L  AG+  NRN+IP D NG WYTSG+RLGTPA+T+ G G D+ + +A++IV+VL N 
Sbjct: 386 ESILRKAGLTVNRNTIPGDQNGPWYTSGIRLGTPAVTTLGMGTDEMNEIADIIVKVLKNA 445

Query: 452 QP----------EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           +P          +  ++   K+ D   +RV+A    +L+  PLYP + +
Sbjct: 446 KPTIVEKTGQLSKANAEIDPKILDEAQQRVNA----ILAKFPLYPEIEI 490


>tr|A6DLM4|A6DLM4_9BACT Tax_Id=313628 SubName: Full=Serine
           hydroxymethyltransferase;[Lentisphaera araneosa
           HTCC2155]
          Length = 504

 Score =  480 bits (1235), Expect = e-133
 Identities = 241/466 (51%), Positives = 313/466 (67%), Gaps = 9/466 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L+ +  V+  + AA  KEL DQR  LK+IASENY S +  LT+G   +DKYAEG   HR+
Sbjct: 29  LEQVAKVDKSIPAAIIKELEDQRSYLKMIASENYCSLSTQLTLGNLLTDKYAEGFPNHRY 88

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC N+D +E  A + A +LFGA +AYVQPHSG DAN+VAFWAIL   V+ P +   G 
Sbjct: 89  YAGCDNIDNLEGQACKEACDLFGAEHAYVQPHSGADANMVAFWAILNKVVQKPYMDKVGE 148

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
            ++ +L++  W  LR   G+Q+LLG++  +GGHLTHG+R N+S +MF   +Y  +P+T  
Sbjct: 149 TNLYNLTDEQWAELRATFGHQKLLGLNYYSGGHLTHGYRHNVSARMFDAYTYDVDPKTQV 208

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYD++   A E KP +L+AGYSAYPR+VNF  MREIAD VGA  MVDMAHFAGLVAGK 
Sbjct: 209 LDYDSIRKQAEEVKPTILLAGYSAYPRKVNFRIMREIADSVGAVFMVDMAHFAGLVAGKA 268

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           FTGD DPV HA V     HK+LRGPRGG++LA +E+   +D+GCPMVLGGPL H M    
Sbjct: 269 FTGDFDPVKHADVVTTTTHKTLRGPRGGLILAKKEFGDFIDQGCPMVLGGPLPHCMAAKA 328

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                   P FQ+YAQ +  N+++LA    +    L +GGTDNH+++LDVT+FGLTGRQA
Sbjct: 329 IAFKEANTPEFQEYAQNIVKNSKSLAGYLSEGGVNLTSGGTDNHLMVLDVTNFGLTGRQA 388

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVL--- 448
           E A+  AGI  NRNS+P DPNGAWYTSG+R+GTPALT+ G G  +   +A++++E+L   
Sbjct: 389 EDAVRAAGITLNRNSVPFDPNGAWYTSGLRIGTPALTTLGMGEAEMKEIAQVVIEILEST 448

Query: 449 -ANTQPEGTSKAKYKLADGTAERVHAAS-----SELLSANPLYPGL 488
            AN    G +  K  LA  T +    AS     + LL+   LYP L
Sbjct: 449 TANIIASGKNAGKKSLAKATTDEAVIASCRERVTNLLNRFVLYPEL 494


>tr|B5JM10|B5JM10_9BACT Tax_Id=382464 RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Verrucomicrobiae
           bacterium DG1235]
          Length = 509

 Score =  469 bits (1207), Expect = e-130
 Identities = 238/468 (50%), Positives = 304/468 (64%), Gaps = 9/468 (1%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           LQ +  V P +A +  KEL DQR +LKLIASENY S      MG   +DKYAEG  G R+
Sbjct: 33  LQQVAEVNPSIAKSIVKELEDQRSNLKLIASENYTSTNTQAAMGNLLTDKYAEGFAGARY 92

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           YAGC N+D +ES A   A ELF A +AYVQPHSG DAN++AFWAIL  +V  P L   G 
Sbjct: 93  YAGCDNIDDIESEACRLACELFKAEHAYVQPHSGADANMIAFWAILQAKVGVPTLEGLGE 152

Query: 152 KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSYGTNPETGF 211
            +   LS  DW  +R  +GNQR+LG+   +GGHLTHG+R N+S + F   SY  +  TG 
Sbjct: 153 PNPAKLSREDWNKVRAAMGNQRMLGLDYYSGGHLTHGYRFNVSAQFFDAYSYSVDEATGL 212

Query: 212 LDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKV 271
           LDYDA+   A E KPL+L+AGYSAYPR+V+F +M+EIAD+VGA LMVDMAHFAGLVAG V
Sbjct: 213 LDYDALEKQAEEVKPLILLAGYSAYPRKVDFRRMKEIADKVGAVLMVDMAHFAGLVAGDV 272

Query: 272 FTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXX 331
           F GD +P+P A V     HK+LRGPRGG+VL  +E+A  +DKGCP+V+GGPL HVM    
Sbjct: 273 FEGDYNPMPFADVVTSTTHKTLRGPRGGIVLCKKEFAEFIDKGCPLVIGGPLPHVMAAKA 332

Query: 332 XXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQA 391
                  +P F+ YA +V +N++ALA   +     + TGG+DNH++L++VTSFGL GRQA
Sbjct: 333 IAFEEALKPEFKAYAARVVENSRALAQAMIDEGLSIATGGSDNHLLLINVTSFGLNGRQA 392

Query: 392 ESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLANT 451
           E+A+ +AG+  NRNS+P DPNG  YTSG+R+GTPA+TS G G D    +A +   +L+NT
Sbjct: 393 EAAVREAGVTLNRNSLPFDPNGPHYTSGLRVGTPAVTSLGMGVDQMKEIAAIFKLILSNT 452

Query: 452 QPE---------GTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           +P            SK KY+L              LL    LY  L L
Sbjct: 453 KPATIATGKNAGKQSKVKYELPAEVIAEARGRVKALLDEFVLYGELDL 500


>tr|Q73JA7|Q73JA7_TREDE Tax_Id=158 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Treponema
           denticola]
          Length = 506

 Score =  459 bits (1182), Expect = e-127
 Identities = 241/472 (51%), Positives = 305/472 (64%), Gaps = 13/472 (2%)

Query: 32  LQVIESVEPRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRF 91
           L  + SV P VA++  KE+ +QR  LKLIASENY+S AV   MG   +DKYAEG   HR+
Sbjct: 27  LDQVASVYPEVASSIVKEIENQRSHLKLIASENYSSLAVQAAMGNLLTDKYAEGFPEHRY 86

Query: 92  YAGCQNVDTVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGA 151
           Y GC+NVD VE  A E A ++FGA +AYVQPHSG DAN+VA+WAIL  +VE P L  F  
Sbjct: 87  YGGCENVDAVEMAACEEACKIFGAEHAYVQPHSGADANIVAYWAILNAKVEEPFLKKFET 146

Query: 152 --------KHINDLSEADWETLRNKLGNQRLLGMSLDAGGHLTHGFRPNISGKMFHQRSY 203
                     +  LS  +WE LR+ LGNQ+L+G+   +GGHLTHG+  N+S KMF   SY
Sbjct: 147 VVDGKVKKMSLEGLSHEEWEELRHALGNQKLMGLDYYSGGHLTHGYVQNVSSKMFRTCSY 206

Query: 204 GTNPETGFLDYDAVAAAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHF 263
             N ETG LDY  +   A E KPL+L+AGYSAYPR++NF K REIAD+ GA LMVDMAHF
Sbjct: 207 TVNKETGELDYAEIEKRAMEEKPLILLAGYSAYPRKINFKKFREIADKCGAVLMVDMAHF 266

Query: 264 AGLVAGKVFTGDEDPVPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPL 323
           AGLVAGKVF G+ +PV  A V     HK+LRGPRG M+L  +E+A  VDKGCP+V+GGPL
Sbjct: 267 AGLVAGKVFEGEYNPVLWADVVTTTTHKTLRGPRGAMILCKKEFAEFVDKGCPLVIGGPL 326

Query: 324 SHVMXXXXXXXXXXRQPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTS 383
            HVM              +Q YA +V DNA ALA+  +K    L T GTDNH++L++VT 
Sbjct: 327 PHVMAAKAVAFREASSKEYQDYAHKVRDNAVALAEECMKLGMKLQTNGTDNHLMLINVTK 386

Query: 384 FGLTGRQAESALLDAGIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAEL 443
           +GL GRQAE+A+ + G+  NRNS+P DPNG W+TSG+R+GTPA+TS G G  +  ++A +
Sbjct: 387 YGLNGRQAETAMSECGVTLNRNSLPFDPNGPWWTSGLRVGTPAVTSLGMGKPEMKQIASI 446

Query: 444 IVEVLANTQPEGT-----SKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           I  VL  ++P  T     SKA   +       +      LL    LYP L L
Sbjct: 447 IDRVLKASKPGVTKSGAPSKANVVVDPAVKAEIQKEVDALLHKFVLYPELDL 498


>sp|B0BC69|GLYA_CHLTB Tax_Id=471473 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Chlamydia trachomatis]
          Length = 497

 Score =  434 bits (1116), Expect = e-119
 Identities = 218/457 (47%), Positives = 306/457 (66%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +  +EL  QR  LK+IASEN++S +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E   AE A+ELFGA  A+VQPHSG DANL+A  +I+  ++++P +   G K INDL E
Sbjct: 97  AIEWECAETAKELFGAESAFVQPHSGADANLLAIMSIITQKIQSPAVQQLGYKTINDLPE 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++E L+ ++   + LG SL++GGHLTHG  R NI  K+ H   Y  N +T   DYD +A
Sbjct: 157 QEYEALKAEMAQHKCLGPSLNSGGHLTHGTVRMNIMSKLMHCLPYEVNLDTELFDYDEIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
             A+E KP VL+AGYS+Y RR NFA +++IA++ GA L VDMAHFAGLVAG VF G+E+P
Sbjct: 217 KIAKEHKPTVLIAGYSSYSRRFNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFVGEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P+A +     HK+LRGPRGG+VLA +EYA  ++K CP+++GGPL HV+           
Sbjct: 277 MPYADIVTTTTHKTLRGPRGGLVLAKKEYANTLNKACPLMMGGPLPHVIAAKAIALKEAM 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA +V +NAQ LA+ F +    L+TGGTDNH++++D+TS G+ GR AE  L   
Sbjct: 337 TINFRKYAHKVVENAQTLAEVFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D +G W TSG+RLGTPALT+ G G+ + + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIVKVLRNITVRSNAE 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            G+SK++ +L++G A+      ++LL   PLYP + L
Sbjct: 457 SGSSKSEGELSEGIAQEARQRVADLLGRFPLYPEIDL 493


>sp|B0B804|GLYA_CHLT2 Tax_Id=471472 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Chlamydia trachomatis]
          Length = 497

 Score =  434 bits (1116), Expect = e-119
 Identities = 218/457 (47%), Positives = 306/457 (66%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +  +EL  QR  LK+IASEN++S +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E   AE A+ELFGA  A+VQPHSG DANL+A  +I+  ++++P +   G K INDL E
Sbjct: 97  AIEWECAETAKELFGAESAFVQPHSGADANLLAIMSIITQKIQSPAVQQLGYKTINDLPE 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++E L+ ++   + LG SL++GGHLTHG  R NI  K+ H   Y  N +T   DYD +A
Sbjct: 157 QEYEALKAEMAQHKCLGPSLNSGGHLTHGTVRMNIMSKLMHCLPYEVNLDTELFDYDEIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
             A+E KP VL+AGYS+Y RR NFA +++IA++ GA L VDMAHFAGLVAG VF G+E+P
Sbjct: 217 KIAKEHKPTVLIAGYSSYSRRFNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFVGEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P+A +     HK+LRGPRGG+VLA +EYA  ++K CP+++GGPL HV+           
Sbjct: 277 MPYADIVTTTTHKTLRGPRGGLVLAKKEYANTLNKACPLMMGGPLPHVIAAKAIALKEAM 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA +V +NAQ LA+ F +    L+TGGTDNH++++D+TS G+ GR AE  L   
Sbjct: 337 TINFRKYAHKVVENAQTLAEVFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D +G W TSG+RLGTPALT+ G G+ + + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIVKVLRNITVRSNAE 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            G+SK++ +L++G A+      ++LL   PLYP + L
Sbjct: 457 SGSSKSEGELSEGIAQEARQRVADLLGRFPLYPEIDL 493


>tr|D3UUP9|D3UUP9_CHLTS Tax_Id=634464 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Chlamydia
           trachomatis serovar E]
          Length = 497

 Score =  434 bits (1115), Expect = e-119
 Identities = 217/457 (47%), Positives = 308/457 (67%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +  +EL  QR  LK+IASEN++S +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E   AE A+ELFGA  A+VQPHSG DANL+A  +I+  ++++P +   G K INDL E
Sbjct: 97  AIEWECAETAKELFGAESAFVQPHSGADANLLAIMSIITQKIQSPAVQRLGYKTINDLPE 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++E L+ ++   + LG SL++GGHLTHG  R NI  K+ H   Y  N +T   DYD +A
Sbjct: 157 QEYEALKAEMAQHKCLGPSLNSGGHLTHGTVRMNIMSKLMHCLPYEVNLDTELFDYDEMA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
             A+E KP VL+AGYS+Y RR+NFA +++IA++ GA L VDMAHFAGLVAG VF G+E+P
Sbjct: 217 KIAKEHKPTVLIAGYSSYSRRLNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFVGEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P+A +     HK+LRGPRGG+VLA +EYA  ++K CP+++GGPL HV+           
Sbjct: 277 MPYADIVTTTTHKTLRGPRGGLVLAKKEYANTLNKACPLMMGGPLPHVIAAKAIALKEAM 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
             +F++YA +V +NA+ LA+ F +    L+TGGTDNH++++D+TS G+ GR AE  L   
Sbjct: 337 TISFRKYAHKVVENARTLAEVFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D +G W TSG+RLGTPALT+ G G+ + + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIVKVLRNITVRSNAE 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            G+SK++ +L++G A+      ++LL   PLYP + L
Sbjct: 457 SGSSKSEGELSEGIAQEARQRVADLLGRFPLYPEIDL 493


>sp|O84439|GLYA_CHLTR Tax_Id=813 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Chlamydia trachomatis]
          Length = 497

 Score =  433 bits (1114), Expect = e-119
 Identities = 217/457 (47%), Positives = 307/457 (67%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +  +EL  QR  LK+IASEN++S +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E   AE A+ELFGA  A+VQPHSG DANL+A  +I+  ++++P +   G K INDL E
Sbjct: 97  AIEWECAETAKELFGAESAFVQPHSGADANLLAIMSIITQKIQSPAVQRLGYKTINDLPE 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++E L+ ++   + LG SL++GGHLTHG  R NI  K+ H   Y  N +T   DYD +A
Sbjct: 157 QEYEALKAEMAQHKCLGPSLNSGGHLTHGTVRMNIMSKLMHCLPYEVNLDTELFDYDEIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
             A+E KP VL+AGYS+Y RR+NFA +++IA++ GA L VDMAHFAGLVAG VF G+E+P
Sbjct: 217 KIAKEHKPTVLIAGYSSYSRRLNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFVGEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P+A +     HK+LRGPRGG+VLA +EYA  ++K CP+++GGPL HV+           
Sbjct: 277 MPYADIVTTTTHKTLRGPRGGLVLAKKEYANTLNKACPLMMGGPLPHVIAAKAIALKEAM 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA +V +NA+ LA+ F +    L+TGGTDNH++++D+TS G+ GR AE  L   
Sbjct: 337 TINFRKYAHKVVENARTLAEVFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D +G W TSG+RLGTPALT+ G G+ + + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIVKVLRNITVRSNAE 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            G+SK++ +L++G A+      ++LL   PLYP + L
Sbjct: 457 SGSSKSEGELSEGIAQEARQRVADLLGRFPLYPEIDL 493


>sp|Q3KLR8|GLYA_CHLTA Tax_Id=315277 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Chlamydia trachomatis]
          Length = 497

 Score =  433 bits (1114), Expect = e-119
 Identities = 217/457 (47%), Positives = 307/457 (67%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +  +EL  QR  LK+IASEN++S +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E   AE A+ELFGA  A+VQPHSG DANL+A  +I+  ++++P +   G K INDL E
Sbjct: 97  AIEWECAETAKELFGAESAFVQPHSGADANLLAIMSIITQKIQSPAVQRLGYKTINDLPE 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++E L+ ++   + LG SL++GGHLTHG  R NI  K+ H   Y  N +T   DYD +A
Sbjct: 157 QEYEALKAEMAQHKCLGPSLNSGGHLTHGTVRMNIMSKLMHCLPYEVNLDTELFDYDEIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
             A+E KP VL+AGYS+Y RR+NFA +++IA++ GA L VDMAHFAGLVAG VF G+E+P
Sbjct: 217 KIAKEHKPTVLIAGYSSYSRRLNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFVGEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P+A +     HK+LRGPRGG+VLA +EYA  ++K CP+++GGPL HV+           
Sbjct: 277 MPYADIVTTTTHKTLRGPRGGLVLAKKEYANTLNKACPLMMGGPLPHVIAAKAIALKEAM 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA +V +NA+ LA+ F +    L+TGGTDNH++++D+TS G+ GR AE  L   
Sbjct: 337 TINFRKYAHKVVENARTLAEVFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D +G W TSG+RLGTPALT+ G G+ + + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIVKVLRNITVRSNAE 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            G+SK++ +L++G A+      ++LL   PLYP + L
Sbjct: 457 SGSSKSEGELSEGIAQEARQRVADLLGRFPLYPEIDL 493


>tr|C4PRB0|C4PRB0_CHLTJ Tax_Id=580049 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Chlamydia
           trachomatis]
          Length = 497

 Score =  433 bits (1114), Expect = e-119
 Identities = 217/457 (47%), Positives = 307/457 (67%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +  +EL  QR  LK+IASEN++S +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E   AE A+ELFGA  A+VQPHSG DANL+A  +I+  ++++P +   G K INDL E
Sbjct: 97  AIEWECAETAKELFGAESAFVQPHSGADANLLAIMSIITQKIQSPAVQRLGYKTINDLPE 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++E L+ ++   + LG SL++GGHLTHG  R NI  K+ H   Y  N +T   DYD +A
Sbjct: 157 QEYEALKAEMAQHKCLGPSLNSGGHLTHGTVRMNIMSKLMHCLPYEVNLDTELFDYDEIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
             A+E KP VL+AGYS+Y RR+NFA +++IA++ GA L VDMAHFAGLVAG VF G+E+P
Sbjct: 217 KIAKEHKPTVLIAGYSSYSRRLNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFVGEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P+A +     HK+LRGPRGG+VLA +EYA  ++K CP+++GGPL HV+           
Sbjct: 277 MPYADIVTTTTHKTLRGPRGGLVLAKKEYANTLNKACPLMMGGPLPHVIAAKAIALKEAM 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA +V +NA+ LA+ F +    L+TGGTDNH++++D+TS G+ GR AE  L   
Sbjct: 337 TINFRKYAHKVVENARTLAEVFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D +G W TSG+RLGTPALT+ G G+ + + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIVKVLRNITVRSNAE 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            G+SK++ +L++G A+      ++LL   PLYP + L
Sbjct: 457 SGSSKSEGELSEGIAQEARQRVADLLGRFPLYPEIDL 493


>tr|C4PMU1|C4PMU1_CHLTZ Tax_Id=672161 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; EC=2.1.2.1;[Chlamydia
           trachomatis]
          Length = 497

 Score =  433 bits (1114), Expect = e-119
 Identities = 217/457 (47%), Positives = 307/457 (67%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +  +EL  QR  LK+IASEN++S +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E   AE A+ELFGA  A+VQPHSG DANL+A  +I+  ++++P +   G K INDL E
Sbjct: 97  AIEWECAETAKELFGAESAFVQPHSGADANLLAIMSIITQKIQSPAVQRLGYKTINDLPE 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++E L+ ++   + LG SL++GGHLTHG  R NI  K+ H   Y  N +T   DYD +A
Sbjct: 157 QEYEALKAEMAQHKCLGPSLNSGGHLTHGTVRMNIMSKLMHCLPYEVNLDTELFDYDEIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
             A+E KP VL+AGYS+Y RR+NFA +++IA++ GA L VDMAHFAGLVAG VF G+E+P
Sbjct: 217 KIAKEHKPTVLIAGYSSYSRRLNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFVGEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P+A +     HK+LRGPRGG+VLA +EYA  ++K CP+++GGPL HV+           
Sbjct: 277 MPYADIVTTTTHKTLRGPRGGLVLAKKEYANTLNKACPLMMGGPLPHVIAAKAIALKEAM 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA +V +NA+ LA+ F +    L+TGGTDNH++++D+TS G+ GR AE  L   
Sbjct: 337 TINFRKYAHKVVENARTLAEVFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D +G W TSG+RLGTPALT+ G G+ + + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIVKVLRNITVRSNAE 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
            G+SK++ +L++G A+      ++LL   PLYP + L
Sbjct: 457 SGSSKSEGELSEGIAQEARQRVADLLGRFPLYPEIDL 493


>sp|Q5L6P4|GLYA_CHLAB Tax_Id=83555 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Chlamydophila abortus]
          Length = 497

 Score =  424 bits (1089), Expect = e-116
 Identities = 217/457 (47%), Positives = 300/457 (65%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +   EL  QR  LK+IASENYAS +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGKSIIDELKSQRSRLKMIASENYASISVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E    E A+ELFGA  A+VQPHSG DANL+A  AI+  +++ P +   G K INDL++
Sbjct: 97  AIEWECVETAKELFGAESAFVQPHSGADANLLAIMAIITQKIQGPAVKRLGYKTINDLTD 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++  L+ ++G+   LG SL++GGHLTHG  R NI  K+     Y  N +T   DY  +A
Sbjct: 157 KEYTELKAEIGSHVCLGPSLNSGGHLTHGTVRLNIMSKLMRCVPYEVNKKTECFDYSEIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
              R +KP VL+AGYS+Y RR+NF+ +++IAD+ GA L VDMAHFAGLVAG VF  +E+P
Sbjct: 217 RLVRTYKPTVLIAGYSSYSRRLNFSTLKQIADDCGAVLWVDMAHFAGLVAGGVFIEEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P A +     HK+LRGPRGG+VLA++EY   +++ CP+++GGPL HV+           
Sbjct: 277 IPFADIITTTTHKTLRGPRGGLVLASKEYDAVINRACPLMMGGPLPHVIAAKAVALKEAL 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA QV DNA+ LA+ F K+   L+TGGTDNH++++D+TS G++GR AE  L   
Sbjct: 337 TVDFKKYAHQVVDNARTLAEHFQKQGLRLLTGGTDNHMLIIDLTSLGISGRIAEDILSSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D  G W TSG+RLGTPALT+ G G+D+ + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDAVGKWDTSGIRLGTPALTTLGMGSDEMEEVANIIVKVLRNITLRRNAD 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           +  SK++ +L +  AE   A  + LLS  PLYP + L
Sbjct: 457 DSFSKSEGELPENIAEEARARVAGLLSRFPLYPEIDL 493


>sp|Q824C8|GLYA_CHLCV Tax_Id=83557 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Chlamydophila caviae]
          Length = 497

 Score =  423 bits (1087), Expect = e-116
 Identities = 217/457 (47%), Positives = 301/457 (65%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +   EL  QR  LK+IASENYAS +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGKSVIDELKGQRSRLKMIASENYASISVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E   AE A+ELFGA  A+VQPHSG DANL+A  AI+  +++ P +   G K INDL++
Sbjct: 97  AIEWECAETAKELFGAESAFVQPHSGADANLLAMMAIITQKIQGPAVKRLGYKTINDLTD 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++  L+ ++G+   LG SL++GGHLTHG  R N+  K+     Y  N +T   DY  +A
Sbjct: 157 KEYAELKAEIGSHVCLGPSLNSGGHLTHGTVRMNVMSKLMRCLPYEVNKKTERFDYAEIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
              R  KP VLVAGYS+Y RR+NF+ +++IAD+ GA L VDMAHFAGLVAG VF  +E+P
Sbjct: 217 RLVRTHKPTVLVAGYSSYSRRLNFSTLKQIADDCGAVLWVDMAHFAGLVAGGVFVEEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P A +     HK+LRGPRGG+VLA++EY   +++ CP+++GGPL HV+           
Sbjct: 277 IPFADIVTTTTHKTLRGPRGGLVLASKEYDGIINRACPLMMGGPLPHVIAAKAVALKEAL 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA QV DNA+ LA+ F K+   L+TGGTDNH++++D+TS G++GR AE  L   
Sbjct: 337 TVDFKKYAHQVVDNARTLAEHFQKQGLRLLTGGTDNHMLIIDLTSLGISGRIAEDILSSI 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN-----TQP 453
           GI  NRN+IP+D  G W TSG+RLGTPALT+ G G+D+ + VA +IV+VL N        
Sbjct: 397 GIAVNRNTIPSDAVGKWDTSGIRLGTPALTTLGMGSDEMEEVANIIVKVLRNITLRRNAD 456

Query: 454 EGTSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           +  SK++ +L +  A+   A  ++LLS  PLYP + L
Sbjct: 457 DSFSKSEGELPENIAQEARARVADLLSRFPLYPEIDL 493


>sp|Q9PJW0|GLYA_CHLMU Tax_Id=83560 (glyA)RecName: Full=Serine
           hydroxymethyltransferase; Short=Serine methylase;
           Short=SHMT; EC=2.1.2.1;[Chlamydia muridarum]
          Length = 497

 Score =  422 bits (1084), Expect = e-116
 Identities = 214/457 (46%), Positives = 303/457 (66%), Gaps = 6/457 (1%)

Query: 40  PRVAAATRKELADQRDSLKLIASENYASPAVLLTMGTWFSDKYAEGTIGHRFYAGCQNVD 99
           P +  +  +EL  QR  LK+IASEN++S +V L MG   +DKY EG+   RFY+ C+NVD
Sbjct: 37  PSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVD 96

Query: 100 TVESVAAEHARELFGAPYAYVQPHSGIDANLVAFWAILATRVEAPELANFGAKHINDLSE 159
            +E    E A+ELFGA  A VQPHSG DANL+A  +I+  ++++P +   G K INDL E
Sbjct: 97  AIEWECVETAKELFGAESACVQPHSGADANLLAIMSIITQKIQSPAVQRLGYKTINDLPE 156

Query: 160 ADWETLRNKLGNQRLLGMSLDAGGHLTHG-FRPNISGKMFHQRSYGTNPETGFLDYDAVA 218
            ++E L+ ++   + LG SL++GGHLTHG  R N+  K+ H   Y  N +T   DYD +A
Sbjct: 157 QEYEALKAEMSQYKCLGPSLNSGGHLTHGTVRINVMSKLMHCLPYEVNLDTELFDYDVIA 216

Query: 219 AAAREFKPLVLVAGYSAYPRRVNFAKMREIADEVGATLMVDMAHFAGLVAGKVFTGDEDP 278
             A+E +P VL+AGYS+Y RR+NFA +++IA++ GA L VDMAHFAGLVAG VF G+E+P
Sbjct: 217 KIAKEHRPTVLIAGYSSYSRRLNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFIGEENP 276

Query: 279 VPHAHVXXXXXHKSLRGPRGGMVLATEEYAPAVDKGCPMVLGGPLSHVMXXXXXXXXXXR 338
           +P+A +     HK+LRGPRGG+VLA +EY+  ++K CP+++GGPL HV+           
Sbjct: 277 IPYADIVTTTTHKTLRGPRGGLVLAKKEYSDTLNKACPLMMGGPLPHVIAAKAVALKEAM 336

Query: 339 QPAFQQYAQQVADNAQALADGFVKRDAGLVTGGTDNHIVLLDVTSFGLTGRQAESALLDA 398
              F++YA QV +NA+ LA+ F +    L+TGGTDNH++++D+TS G+ GR AE  L   
Sbjct: 337 TINFRKYAHQVVENARTLAEIFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSV 396

Query: 399 GIVTNRNSIPADPNGAWYTSGVRLGTPALTSRGFGADDFDRVAELIVEVLAN----TQPE 454
           GI  NRNSIP+D +G W TSG+RLGTPALT+ G G+ + + VA +I +VL N       E
Sbjct: 397 GIAVNRNSIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIAKVLRNITVRRNAE 456

Query: 455 G-TSKAKYKLADGTAERVHAASSELLSANPLYPGLTL 490
           G +SK++  L++  A+      ++LL   PLYP + L
Sbjct: 457 GSSSKSEGVLSEEIAQEARQRVADLLGRFPLYPEIDL 493


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.317    0.133    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 3,735,782,810
Number of extensions: 156192513
Number of successful extensions: 369223
Number of sequences better than 10.0: 3152
Number of HSP's gapped: 361777
Number of HSP's successfully gapped: 5712
Length of query: 490
Length of database: 4,236,830,644
Length adjustment: 142
Effective length of query: 348
Effective length of database: 2,460,713,956
Effective search space: 856328456688
Effective search space used: 856328456688
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 83 (36.6 bits)