BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_5436 (322 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|A0R3D7|ISPE_MYCS2 Tax_Id=246196 (ispE)RecName: Full=4-diphosp... 604 e-171 sp|A1TEH2|ISPE_MYCVP Tax_Id=350058 (ispE)RecName: Full=4-diphosp... 498 e-139 sp|A4T6N7|ISPE_MYCGI Tax_Id=350054 (ispE)RecName: Full=4-diphosp... 496 e-138 tr|Q1B417|Q1B417_MYCSS Tax_Id=164756 SubName: Full=4-diphosphocy... 482 e-134 tr|A3Q5H9|A3Q5H9_MYCSJ Tax_Id=164757 SubName: Full=4-diphosphocy... 482 e-134 tr|A1UL31|A1UL31_MYCSK Tax_Id=189918 SubName: Full=4-diphosphocy... 482 e-134 tr|D5PFI9|D5PFI9_9MYCO Tax_Id=525368 (ispE)SubName: Full=4-dipho... 465 e-129 tr|A2VGU4|A2VGU4_MYCTU Tax_Id=348776 (ispE)RecName: Full=4-dipho... 457 e-127 sp|Q741W1|ISPE_MYCPA Tax_Id=1770 (ispE)RecName: Full=4-diphospho... 453 e-125 sp|A0PW69|ISPE_MYCUA Tax_Id=362242 (ispE)RecName: Full=4-diphosp... 445 e-123 sp|B2HDJ9|ISPE_MYCMM Tax_Id=216594 (ispE)RecName: Full=4-diphosp... 443 e-122 sp|P65178|ISPE_MYCTU Tax_Id=1773 (ispE)RecName: Full=4-diphospho... 442 e-122 sp|A5U154|ISPE_MYCTA Tax_Id=419947 (ispE)RecName: Full=4-diphosp... 442 e-122 sp|C1AM02|ISPE_MYCBT Tax_Id=561275 (ispE)RecName: Full=4-diphosp... 442 e-122 sp|A1KHE9|ISPE_MYCBP Tax_Id=410289 (ispE)RecName: Full=4-diphosp... 442 e-122 sp|P65179|ISPE_MYCBO Tax_Id=1765 (ispE)RecName: Full=4-diphospho... 442 e-122 tr|C6DVU2|C6DVU2_MYCTK Tax_Id=478434 (ispE)RecName: Full=4-dipho... 442 e-122 tr|A5WL34|A5WL34_MYCTF Tax_Id=336982 (ispE)RecName: Full=4-dipho... 442 e-122 tr|D6G112|D6G112_MYCTU Tax_Id=478435 SubName: Full=4-diphosphocy... 442 e-122 tr|D6FPR3|D6FPR3_MYCTU Tax_Id=611304 SubName: Full=4-diphosphocy... 442 e-122 tr|D6FFJ4|D6FFJ4_MYCTU Tax_Id=611303 SubName: Full=4-diphosphocy... 442 e-122 tr|D6F2V0|D6F2V0_MYCTU Tax_Id=611302 SubName: Full=4-(Cytidine 5... 442 e-122 tr|D5ZE90|D5ZE90_MYCTU Tax_Id=537210 SubName: Full=4-diphosphocy... 442 e-122 tr|D5Z1Q4|D5Z1Q4_MYCTU Tax_Id=537209 SubName: Full=4-diphosphocy... 442 e-122 tr|D5YPY1|D5YPY1_MYCTU Tax_Id=515616 SubName: Full=4-diphosphocy... 442 e-122 tr|D5YDJ3|D5YDJ3_MYCTU Tax_Id=520140 SubName: Full=4-(Cytidine-5... 442 e-122 tr|D5Y1Y6|D5Y1Y6_MYCTU Tax_Id=520141 SubName: Full=4-(Cytidine-5... 442 e-122 tr|D5XRW6|D5XRW6_MYCTU Tax_Id=515617 SubName: Full=4-diphosphocy... 442 e-122 tr|A4KFV1|A4KFV1_MYCTU Tax_Id=395095 (ispE)RecName: Full=4-dipho... 442 e-122 sp|A0QBW1|ISPE_MYCA1 Tax_Id=243243 (ispE)RecName: Full=4-diphosp... 440 e-121 tr|B1MKD5|B1MKD5_MYCA9 Tax_Id=561007 (ispE)RecName: Full=4-dipho... 423 e-116 sp|Q9CD51|ISPE_MYCLE Tax_Id=1769 (ispE)RecName: Full=4-diphospho... 417 e-115 sp|B8ZU60|ISPE_MYCLB Tax_Id=561304 (ispE)RecName: Full=4-diphosp... 417 e-115 tr|D5PX33|D5PX33_COREQ Tax_Id=525370 (ispE)SubName: Full=4-(Cyti... 365 6e-99 tr|C1A375|C1A375_RHOE4 Tax_Id=234621 (ispE)SubName: Full=4-dipho... 363 1e-98 tr|C3JWT9|C3JWT9_RHOER Tax_Id=596309 (ispE)SubName: Full=4-(Cyti... 359 2e-97 sp|Q5YPY8|ISPE_NOCFA Tax_Id=37329 (ispE)RecName: Full=4-diphosph... 357 9e-97 tr|C1AXZ7|C1AXZ7_RHOOB Tax_Id=632772 (ispE)SubName: Full=4-dipho... 355 4e-96 sp|Q0S4S3|ISPE_RHOSR Tax_Id=101510 (ispE)RecName: Full=4-diphosp... 353 2e-95 sp|A4F7X3|ISPE_SACEN Tax_Id=405948 (ispE)RecName: Full=4-diphosp... 348 5e-94 tr|C7MZI6|C7MZI6_SACVD Tax_Id=471857 (ispE)RecName: Full=4-dipho... 343 1e-92 tr|C6WJI0|C6WJI0_ACTMD Tax_Id=446462 (ispE)RecName: Full=4-dipho... 343 2e-92 tr|D5UVN4|D5UVN4_TSUPA Tax_Id=521096 SubName: Full=4-diphosphocy... 334 1e-89 tr|D0L708|D0L708_GORB4 Tax_Id=526226 (ispE)RecName: Full=4-dipho... 320 2e-85 tr|C7PYX1|C7PYX1_CATAD Tax_Id=479433 (ispE)RecName: Full=4-dipho... 313 1e-83 >sp|A0R3D7|ISPE_MYCS2 Tax_Id=246196 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium smegmatis] Length = 322 Score = 604 bits (1557), Expect = e-171 Identities = 309/322 (95%), Positives = 309/322 (95%) Query: 1 MAVPASDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTV 60 MAVPASDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTV Sbjct: 1 MAVPASDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTV 60 Query: 61 RNADVLSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXX 120 RNADVLSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPV Sbjct: 61 RNADVLSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVAGGMAGG 120 Query: 121 XXXXXXVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARN 180 VLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARN Sbjct: 121 SADAAGVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARN 180 Query: 181 TFHWVLAFAHRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGN 240 TFHWVLAFAHRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGN Sbjct: 181 TFHWVLAFAHRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGN 240 Query: 241 DLQPAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVC 300 DLQPAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVC Sbjct: 241 DLQPAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVC 300 Query: 301 RTVRVASGPVHGAHVVPAPSAS 322 RTVRVASGPVHGAHVVPAPSAS Sbjct: 301 RTVRVASGPVHGAHVVPAPSAS 322 >sp|A1TEH2|ISPE_MYCVP Tax_Id=350058 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium vanbaalenii] Length = 322 Score = 498 bits (1281), Expect = e-139 Identities = 255/317 (80%), Positives = 276/317 (87%), Gaps = 1/317 (0%) Query: 5 ASDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNAD 64 A DG+TASEWV TGSVTVRVPGKVNLYL VGD RDDGYH+LTTVFHAVSLLDEVTVR AD Sbjct: 3 ARDGNTASEWVPTGSVTVRVPGKVNLYLDVGDRRDDGYHELTTVFHAVSLLDEVTVRTAD 62 Query: 65 VLSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXX 124 +LSL M GEGAESLP DERNLAWRAAELMA+HVGR+PDV I+IEK+IPV Sbjct: 63 ILSLEMTGEGAESLPTDERNLAWRAAELMADHVGRSPDVAISIEKTIPVAGGMAGGSADA 122 Query: 125 XXVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHW 184 VLVAMN+LWELGVPRRDLHALAAQLGSDVPFALHGGTALG+GRGE+LATVL RNTFHW Sbjct: 123 AAVLVAMNSLWELGVPRRDLHALAAQLGSDVPFALHGGTALGTGRGEELATVLTRNTFHW 182 Query: 185 VLAFAHRGLSTPKVFGELDRLRADTTRGL-PRTDEPEPVLAALASGDPAELAALLGNDLQ 243 VLAF+ GLST KVF E+DRLRA+ R L PR + PEPVLAALASGDPA+LA LLGNDLQ Sbjct: 183 VLAFSPGGLSTAKVFAEIDRLRAEEDRTLPPRLESPEPVLAALASGDPAQLAPLLGNDLQ 242 Query: 244 PAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTV 303 PAALSL LRRTLRAGV+AGALAG+VSGSGPTCAFLC SA AA+DVGT+L+GAGVCRTV Sbjct: 243 PAALSLDSTLRRTLRAGVDAGALAGVVSGSGPTCAFLCGSAGAAVDVGTELAGAGVCRTV 302 Query: 304 RVASGPVHGAHVVPAPS 320 RVASGPV GA VVP+PS Sbjct: 303 RVASGPVQGARVVPSPS 319 >sp|A4T6N7|ISPE_MYCGI Tax_Id=350054 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium gilvum] Length = 322 Score = 496 bits (1276), Expect = e-138 Identities = 254/319 (79%), Positives = 275/319 (86%), Gaps = 1/319 (0%) Query: 5 ASDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNAD 64 A DG+TASEWV TGSVTVRVPGKVNLYL VGD R DGYH+LTTVFHAVSLLDEVTVR AD Sbjct: 3 ARDGNTASEWVPTGSVTVRVPGKVNLYLDVGDRRQDGYHELTTVFHAVSLLDEVTVRTAD 62 Query: 65 VLSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXX 124 LSL +GEGA+SLP DERNLAWRAAELMAEHVGRAPDV I+IEK+IPV Sbjct: 63 TLSLEHVGEGADSLPTDERNLAWRAAELMAEHVGRAPDVAISIEKTIPVAGGMAGGSADA 122 Query: 125 XXVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHW 184 VLVAMN+LWELGVPRRDLHALAAQLGSDVPFALHGGTALG+GRGE+LATVL RNTFHW Sbjct: 123 AAVLVAMNSLWELGVPRRDLHALAAQLGSDVPFALHGGTALGTGRGEELATVLTRNTFHW 182 Query: 185 VLAFAHRGLSTPKVFGELDRLRADTTRGL-PRTDEPEPVLAALASGDPAELAALLGNDLQ 243 VLAF+ GLST KVF E+DRLRA+ R L PR + PEPVLAALASGDPA+LA LLGNDLQ Sbjct: 183 VLAFSPGGLSTAKVFAEIDRLRAEEDRTLPPRLESPEPVLAALASGDPAQLAPLLGNDLQ 242 Query: 244 PAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTV 303 PAALSL P LRRTLRAG++AGALAG+VSGSGPTCAFLC SA AA+D+GT L+GAGVCRTV Sbjct: 243 PAALSLDPALRRTLRAGLDAGALAGLVSGSGPTCAFLCTSAGAAVDIGTDLAGAGVCRTV 302 Query: 304 RVASGPVHGAHVVPAPSAS 322 RVASGPV GA VVPAPS + Sbjct: 303 RVASGPVQGARVVPAPSTA 321 >tr|Q1B417|Q1B417_MYCSS Tax_Id=164756 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; EC=2.7.1.148;[Mycobacterium sp.] Length = 322 Score = 482 bits (1241), Expect = e-134 Identities = 249/319 (78%), Positives = 273/319 (85%), Gaps = 3/319 (0%) Query: 7 DGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVL 66 +G+TASEWV TGSVTVRVPGKVNL+L VGDLRDDGYHDLTTVFHAVSLLDEVTV AD L Sbjct: 3 NGNTASEWVPTGSVTVRVPGKVNLFLGVGDLRDDGYHDLTTVFHAVSLLDEVTVSTADTL 62 Query: 67 SLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXX 126 SL + GEGAESLP D RNLAW+AAELMAEHVGR+PDV I+IEKSIPV Sbjct: 63 SLDLAGEGAESLPTDRRNLAWKAAELMAEHVGRSPDVAISIEKSIPVAGGMAGGSADAAG 122 Query: 127 VLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVL 186 VLVAMN LWE+GVPRRDLHA+AA+LGSDVPFALHGGTALG+GRGE+LATVLAR+TFHWVL Sbjct: 123 VLVAMNHLWEIGVPRRDLHAMAAELGSDVPFALHGGTALGTGRGEELATVLARSTFHWVL 182 Query: 187 AFAHRGLSTPKVFGELDRLR--ADTTRGLP-RTDEPEPVLAALASGDPAELAALLGNDLQ 243 AFA++GLSTPKVF ELDRLR A R P R +PEP+LAALASGD +LA LLGNDLQ Sbjct: 183 AFAYKGLSTPKVFRELDRLRATAGAARAEPARLGDPEPMLAALASGDARQLAPLLGNDLQ 242 Query: 244 PAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTV 303 AALSL PDLRRTLRAG++AGALA IVSGSGPTCAFLCAS+P A+DVG +L+GAGVCRTV Sbjct: 243 AAALSLSPDLRRTLRAGLDAGALAAIVSGSGPTCAFLCASSPQAIDVGARLAGAGVCRTV 302 Query: 304 RVASGPVHGAHVVPAPSAS 322 RVASGPV GA VVPAPS S Sbjct: 303 RVASGPVQGARVVPAPSPS 321 >tr|A3Q5H9|A3Q5H9_MYCSJ Tax_Id=164757 SubName: Full=4-diphosphocytidyl-2C-methyl-D-erythritol kinase;[Mycobacterium sp.] Length = 322 Score = 482 bits (1241), Expect = e-134 Identities = 249/319 (78%), Positives = 273/319 (85%), Gaps = 3/319 (0%) Query: 7 DGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVL 66 +G+TASEWV TGSVTVRVPGKVNL+L VGDLRDDGYHDLTTVFHAVSLLDEVTV AD L Sbjct: 3 NGNTASEWVPTGSVTVRVPGKVNLFLGVGDLRDDGYHDLTTVFHAVSLLDEVTVSTADTL 62 Query: 67 SLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXX 126 SL + GEGAESLP D RNLAW+AAELMAEHVGR+PDV I+IEKSIPV Sbjct: 63 SLDLAGEGAESLPTDRRNLAWKAAELMAEHVGRSPDVAISIEKSIPVAGGMAGGSADAAG 122 Query: 127 VLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVL 186 VLVAMN LWE+GVPRRDLHA+AA+LGSDVPFALHGGTALG+GRGE+LATVLAR+TFHWVL Sbjct: 123 VLVAMNHLWEIGVPRRDLHAMAAELGSDVPFALHGGTALGTGRGEELATVLARSTFHWVL 182 Query: 187 AFAHRGLSTPKVFGELDRLR--ADTTRGLP-RTDEPEPVLAALASGDPAELAALLGNDLQ 243 AFA++GLSTPKVF ELDRLR A R P R +PEP+LAALASGD +LA LLGNDLQ Sbjct: 183 AFAYKGLSTPKVFRELDRLRATAGAARAEPARLGDPEPMLAALASGDARQLAPLLGNDLQ 242 Query: 244 PAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTV 303 AALSL PDLRRTLRAG++AGALA IVSGSGPTCAFLCAS+P A+DVG +L+GAGVCRTV Sbjct: 243 AAALSLSPDLRRTLRAGLDAGALAAIVSGSGPTCAFLCASSPQAIDVGARLAGAGVCRTV 302 Query: 304 RVASGPVHGAHVVPAPSAS 322 RVASGPV GA VVPAPS S Sbjct: 303 RVASGPVQGARVVPAPSPS 321 >tr|A1UL31|A1UL31_MYCSK Tax_Id=189918 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; EC=2.7.1.148;[Mycobacterium sp.] Length = 322 Score = 482 bits (1241), Expect = e-134 Identities = 249/319 (78%), Positives = 273/319 (85%), Gaps = 3/319 (0%) Query: 7 DGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVL 66 +G+TASEWV TGSVTVRVPGKVNL+L VGDLRDDGYHDLTTVFHAVSLLDEVTV AD L Sbjct: 3 NGNTASEWVPTGSVTVRVPGKVNLFLGVGDLRDDGYHDLTTVFHAVSLLDEVTVSTADTL 62 Query: 67 SLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXX 126 SL + GEGAESLP D RNLAW+AAELMAEHVGR+PDV I+IEKSIPV Sbjct: 63 SLDLAGEGAESLPTDRRNLAWKAAELMAEHVGRSPDVAISIEKSIPVAGGMAGGSADAAG 122 Query: 127 VLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVL 186 VLVAMN LWE+GVPRRDLHA+AA+LGSDVPFALHGGTALG+GRGE+LATVLAR+TFHWVL Sbjct: 123 VLVAMNHLWEIGVPRRDLHAMAAELGSDVPFALHGGTALGTGRGEELATVLARSTFHWVL 182 Query: 187 AFAHRGLSTPKVFGELDRLR--ADTTRGLP-RTDEPEPVLAALASGDPAELAALLGNDLQ 243 AFA++GLSTPKVF ELDRLR A R P R +PEP+LAALASGD +LA LLGNDLQ Sbjct: 183 AFAYKGLSTPKVFRELDRLRATAGAARAEPARLGDPEPMLAALASGDARQLAPLLGNDLQ 242 Query: 244 PAALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTV 303 AALSL PDLRRTLRAG++AGALA IVSGSGPTCAFLCAS+P A+DVG +L+GAGVCRTV Sbjct: 243 AAALSLSPDLRRTLRAGLDAGALAAIVSGSGPTCAFLCASSPQAIDVGARLAGAGVCRTV 302 Query: 304 RVASGPVHGAHVVPAPSAS 322 RVASGPV GA VVPAPS S Sbjct: 303 RVASGPVQGARVVPAPSPS 321 >tr|D5PFI9|D5PFI9_9MYCO Tax_Id=525368 (ispE)SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; EC=2.7.1.148;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 316 Score = 465 bits (1196), Expect = e-129 Identities = 240/315 (76%), Positives = 267/315 (84%), Gaps = 2/315 (0%) Query: 6 SDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADV 65 SDG+TA++WV TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVF AVSLLDEVTVRNADV Sbjct: 2 SDGNTAAQWVPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFQAVSLLDEVTVRNADV 61 Query: 66 LSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXX 125 LSL ++GEGA++LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV Sbjct: 62 LSLELVGEGADTLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAA 121 Query: 126 XVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWV 185 VLVAMN+LWEL VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWV Sbjct: 122 AVLVAMNSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWV 181 Query: 186 LAFAHRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPA 245 LAFA L TP VFGELDRLR PR P PVLAALA+GD +LA+LLGN++Q A Sbjct: 182 LAFADGELLTPSVFGELDRLR--EAGDPPRLGGPGPVLAALAAGDAEQLASLLGNEMQAA 239 Query: 246 ALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRV 305 A+SL P LRRTLRAGVEAGALAGIVSGSGPTCAFLC SA AA+DVGT++SGAGVCRTVRV Sbjct: 240 AVSLNPKLRRTLRAGVEAGALAGIVSGSGPTCAFLCGSAGAAVDVGTEVSGAGVCRTVRV 299 Query: 306 ASGPVHGAHVVPAPS 320 ASGPV GA VVPAP+ Sbjct: 300 ASGPVAGARVVPAPT 314 >tr|A2VGU4|A2VGU4_MYCTU Tax_Id=348776 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Mycobacterium tuberculosis C] Length = 318 Score = 457 bits (1177), Expect = e-127 Identities = 237/316 (75%), Positives = 262/316 (82%), Gaps = 2/316 (0%) Query: 5 ASDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNAD 64 ASDG+TA WV TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNAD Sbjct: 3 ASDGNTAELWVPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNAD 62 Query: 65 VLSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXX 124 VLSL ++GEGA+ LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV Sbjct: 63 VLSLELVGEGADQLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADA 122 Query: 125 XXVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHW 184 VLVAMN+LWEL VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHW Sbjct: 123 AAVLVAMNSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHW 182 Query: 185 VLAFAHRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQP 244 VLAFA GL T V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q Sbjct: 183 VLAFADSGLLTSAVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQA 240 Query: 245 AALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVR 304 AA+SL P L R LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVR Sbjct: 241 AAVSLDPALARALRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVR 300 Query: 305 VASGPVHGAHVVPAPS 320 VA+GPV GA VV AP+ Sbjct: 301 VATGPVPGARVVSAPT 316 >sp|Q741W1|ISPE_MYCPA Tax_Id=1770 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium paratuberculosis] Length = 316 Score = 453 bits (1165), Expect = e-125 Identities = 235/315 (74%), Positives = 262/315 (83%), Gaps = 2/315 (0%) Query: 6 SDGSTASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADV 65 SDG+TA+ WV TGSVTVRVPGKVNLYL+VGD R+DGYH+LTT+F AVSLLDEVTVRNADV Sbjct: 2 SDGNTAAAWVPTGSVTVRVPGKVNLYLAVGDRREDGYHELTTIFQAVSLLDEVTVRNADV 61 Query: 66 LSLRMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXX 125 LSL ++GEGA+ LP DERNLAW+AAELMA+HVGRAPDV I I+KSIPV Sbjct: 62 LSLDIVGEGADKLPTDERNLAWQAAELMADHVGRAPDVSIMIDKSIPVAGGMAGGSADAA 121 Query: 126 XVLVAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWV 185 VLVAMN+LWEL VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWV Sbjct: 122 AVLVAMNSLWELNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWV 181 Query: 186 LAFAHRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPA 245 LAFA L T KVF ELDRLR PR P PVLAALA+GD +LA LLGN++Q A Sbjct: 182 LAFADGELLTRKVFAELDRLR--RAGDPPRLPGPGPVLAALAAGDADQLAPLLGNEMQAA 239 Query: 246 ALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRV 305 A+SL P LRRTLRAGV+AGALAGIVSGSGPTCAFLC SA AA+DVGT++SG GVCRTVRV Sbjct: 240 AVSLNPGLRRTLRAGVQAGALAGIVSGSGPTCAFLCPSAAAAVDVGTEVSGVGVCRTVRV 299 Query: 306 ASGPVHGAHVVPAPS 320 ASGPV GA VVPAP+ Sbjct: 300 ASGPVAGARVVPAPT 314 >sp|A0PW69|ISPE_MYCUA Tax_Id=362242 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium ulcerans] Length = 307 Score = 445 bits (1145), Expect = e-123 Identities = 229/303 (75%), Positives = 253/303 (83%), Gaps = 2/303 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGS TVRVPGKVNLYL+VGD RDDGYH+LTTVFHAVSL+DEVTVRNAD+LSL ++GEGA+ Sbjct: 3 TGSATVRVPGKVNLYLAVGDRRDDGYHELTTVFHAVSLVDEVTVRNADLLSLEVVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP D+RNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 KLPTDKRNLAWQAAELMAEHVGRAPDVSIFIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L +PRRDL LAAQLGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GLSTP Sbjct: 123 LNLPRRDLRMLAAQLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFARSGLSTP 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 VF ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P LRR Sbjct: 183 AVFTELDRLR--DVGSPPRLAEPGPVLAALAAGDPEQLAPLLGNEMQAAAVSLDPALRRA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC +A +ALDV QLSGAGVCRTVR+A+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCRTAESALDVSAQLSGAGVCRTVRIATGPVPGARVV 300 Query: 317 PAP 319 P P Sbjct: 301 PTP 303 >sp|B2HDJ9|ISPE_MYCMM Tax_Id=216594 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium marinum] Length = 307 Score = 443 bits (1140), Expect = e-122 Identities = 228/303 (75%), Positives = 253/303 (83%), Gaps = 2/303 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGS TVRVPGKVNLYL+VGD RDDGYH+LTTVFHAVSL+DEVTVRNAD+LSL ++GEGA+ Sbjct: 3 TGSATVRVPGKVNLYLAVGDRRDDGYHELTTVFHAVSLVDEVTVRNADLLSLEVVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP D+RNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 RLPTDKRNLAWQAAELMAEHVGRAPDVSIFIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L +PRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GLSTP Sbjct: 123 LNLPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFARSGLSTP 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 VF ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P LRR Sbjct: 183 AVFTELDRLR--DVGSPPRLAEPGPVLAALAAGDPEQLAPLLGNEMQAAAVSLDPALRRA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC +A +ALDV QLSGAGVCRTVR+A+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCRTAESALDVSAQLSGAGVCRTVRIATGPVPGARVV 300 Query: 317 PAP 319 P P Sbjct: 301 PTP 303 >sp|P65178|ISPE_MYCTU Tax_Id=1773 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium tuberculosis] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >sp|A5U154|ISPE_MYCTA Tax_Id=419947 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium tuberculosis] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >sp|C1AM02|ISPE_MYCBT Tax_Id=561275 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium bovis] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >sp|A1KHE9|ISPE_MYCBP Tax_Id=410289 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium bovis] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >sp|P65179|ISPE_MYCBO Tax_Id=1765 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium bovis] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|C6DVU2|C6DVU2_MYCTK Tax_Id=478434 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Mycobacterium tuberculosis] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|A5WL34|A5WL34_MYCTF Tax_Id=336982 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Mycobacterium tuberculosis] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D6G112|D6G112_MYCTU Tax_Id=478435 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE;[Mycobacterium tuberculosis KZN 605] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D6FPR3|D6FPR3_MYCTU Tax_Id=611304 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE;[Mycobacterium tuberculosis K85] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D6FFJ4|D6FFJ4_MYCTU Tax_Id=611303 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE;[Mycobacterium tuberculosis CPHL_A] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D6F2V0|D6F2V0_MYCTU Tax_Id=611302 SubName: Full=4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium tuberculosis T46] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D5ZE90|D5ZE90_MYCTU Tax_Id=537210 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE;[Mycobacterium tuberculosis T17] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D5Z1Q4|D5Z1Q4_MYCTU Tax_Id=537209 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE;[Mycobacterium tuberculosis GM 1503] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D5YPY1|D5YPY1_MYCTU Tax_Id=515616 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase;[Mycobacterium tuberculosis 02_1987] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D5YDJ3|D5YDJ3_MYCTU Tax_Id=520140 SubName: Full=4-(Cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium tuberculosis EAS054] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D5Y1Y6|D5Y1Y6_MYCTU Tax_Id=520141 SubName: Full=4-(Cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium tuberculosis T85] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|D5XRW6|D5XRW6_MYCTU Tax_Id=515617 SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase ispE;[Mycobacterium tuberculosis T92] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >tr|A4KFV1|A4KFV1_MYCTU Tax_Id=395095 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Mycobacterium tuberculosis str. Haarlem] Length = 306 Score = 442 bits (1136), Expect = e-122 Identities = 229/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTTVFHAVSL+DEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTVRNADVLSLELVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 QLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA GL T Sbjct: 123 LNVPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADSGLLTS 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ ELDRLR PR EP PVLAALA+GDP +LA LLGN++Q AA+SL P L R Sbjct: 183 AVYNELDRLR--EVGDPPRLGEPGPVLAALAAGDPDQLAPLLGNEMQAAAVSLDPALARA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGVEAGALAGIVSGSGPTCAFLC SA +A+DVG QLSGAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGVEAGALAGIVSGSGPTCAFLCTSASSAIDVGAQLSGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAPS 320 AP+ Sbjct: 301 SAPT 304 >sp|A0QBW1|ISPE_MYCA1 Tax_Id=243243 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium avium] Length = 306 Score = 440 bits (1132), Expect = e-121 Identities = 230/304 (75%), Positives = 253/304 (83%), Gaps = 2/304 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTVRVPGKVNLYL+VGD R+DGYH+LTT+F AVSLLDEVTVRNADVLSL ++GEGA+ Sbjct: 3 TGSVTVRVPGKVNLYLAVGDRREDGYHELTTIFQAVSLLDEVTVRNADVLSLDIVGEGAD 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 LP DERNLAW+AAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 KLPTDERNLAWQAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L VPRRDL LAAQLGSDVPFALHGGTALG+GRGE+LATVL+RNTFHWVLAFA L T Sbjct: 123 LNVPRRDLRMLAAQLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFADGELLTR 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 KVF ELDRLR PR P PVLAALA+GD +LA LLGN++Q AA+SL P LRRT Sbjct: 183 KVFAELDRLR--RAGDPPRLPGPGPVLAALAAGDADQLAPLLGNEMQAAAVSLNPGLRRT 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGV+AGALAGIVSGSGPTCAFLC SA AA+DVGT++SG GVCRTVRVASGPV GA VV Sbjct: 241 LRAGVQAGALAGIVSGSGPTCAFLCPSAAAAVDVGTEVSGVGVCRTVRVASGPVAGARVV 300 Query: 317 PAPS 320 PAP+ Sbjct: 301 PAPT 304 >tr|B1MKD5|B1MKD5_MYCA9 Tax_Id=561007 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Mycobacterium abscessus] Length = 314 Score = 423 bits (1088), Expect = e-116 Identities = 217/311 (69%), Positives = 246/311 (79%), Gaps = 2/311 (0%) Query: 10 TASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLR 69 T S+WV TG+VTVR PGKVNLYL+VGDLRDDGYH+LTTVFHAVSL D+VTVR+ADVLS+ Sbjct: 4 TVSDWVPTGAVTVRAPGKVNLYLAVGDLRDDGYHELTTVFHAVSLADDVTVRDADVLSID 63 Query: 70 MIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLV 129 ++G+G ++P DERNLAW+AAEL A+HVGRAPDV I I K IPV VLV Sbjct: 64 VVGQGEGTVPTDERNLAWQAAELFADHVGRAPDVSIFINKDIPVAGGMAGGSADAAAVLV 123 Query: 130 AMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFA 189 AMN LW GVPRRDLH LAAQLGSDVPFALHGGTALG+GRGE LATVLARN FHWV AFA Sbjct: 124 AMNELWHAGVPRRDLHHLAAQLGSDVPFALHGGTALGTGRGEQLATVLARNVFHWVFAFA 183 Query: 190 HRGLSTPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSL 249 GL+TP+VF E+DRLR + PR E + +L ALA+GD LA LLGN+LQ AA+SL Sbjct: 184 DGGLATPQVFKEIDRLRENGDP--PRLAEADELLGALAAGDARRLAPLLGNELQAAAVSL 241 Query: 250 YPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGP 309 P+LRRTLRAG AGALAGIVSGSGPTCAFLC SA A+ V +L+GAGVCRTVRVASGP Sbjct: 242 NPELRRTLRAGESAGALAGIVSGSGPTCAFLCTSADDAVQVSAELAGAGVCRTVRVASGP 301 Query: 310 VHGAHVVPAPS 320 VHGA V+ S Sbjct: 302 VHGAQVIQGRS 312 >sp|Q9CD51|ISPE_MYCLE Tax_Id=1769 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium leprae] Length = 311 Score = 417 bits (1073), Expect = e-115 Identities = 217/303 (71%), Positives = 245/303 (80%), Gaps = 2/303 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTV+VPGK+NLYL+VGD D+GYH+L TVFHAVSL+D+VTVRNADVLSL ++GEGA Sbjct: 3 TGSVTVQVPGKINLYLAVGDCCDNGYHELVTVFHAVSLVDQVTVRNADVLSLGLVGEGAN 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 +P DE N+AWRAAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 HVPTDEHNIAWRAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L +PRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+R TFHWVLAFA L TP Sbjct: 123 LSLPRRDLCMLAAKLGSDVPFALHGGTALGTGRGEELATVLSRATFHWVLAFADSSLLTP 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ E DRLR PR EP PVLAAL + DP +LA LLGN+LQ AA+SL P LR Sbjct: 183 AVYTEFDRLR--DVGNPPRLAEPGPVLAALVAADPEQLAPLLGNELQAAAVSLDPALRCA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAG+EAGALAGIVSGSGPTCAFLCASA +A+DVG QL+GAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGMEAGALAGIVSGSGPTCAFLCASATSAIDVGAQLAGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAP 319 AP Sbjct: 301 HAP 303 >sp|B8ZU60|ISPE_MYCLB Tax_Id=561304 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Mycobacterium leprae] Length = 311 Score = 417 bits (1073), Expect = e-115 Identities = 217/303 (71%), Positives = 245/303 (80%), Gaps = 2/303 (0%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 TGSVTV+VPGK+NLYL+VGD D+GYH+L TVFHAVSL+D+VTVRNADVLSL ++GEGA Sbjct: 3 TGSVTVQVPGKINLYLAVGDCCDNGYHELVTVFHAVSLVDQVTVRNADVLSLGLVGEGAN 62 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 +P DE N+AWRAAELMAEHVGRAPDV I I+KSIPV VLVAMN+LWE Sbjct: 63 HVPTDEHNIAWRAAELMAEHVGRAPDVSIMIDKSIPVAGGMAGGSADAAAVLVAMNSLWE 122 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L +PRRDL LAA+LGSDVPFALHGGTALG+GRGE+LATVL+R TFHWVLAFA L TP Sbjct: 123 LSLPRRDLCMLAAKLGSDVPFALHGGTALGTGRGEELATVLSRATFHWVLAFADSSLLTP 182 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 V+ E DRLR PR EP PVLAAL + DP +LA LLGN+LQ AA+SL P LR Sbjct: 183 AVYTEFDRLR--DVGNPPRLAEPGPVLAALVAADPEQLAPLLGNELQAAAVSLDPALRCA 240 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAG+EAGALAGIVSGSGPTCAFLCASA +A+DVG QL+GAGVCRTVRVA+GPV GA VV Sbjct: 241 LRAGMEAGALAGIVSGSGPTCAFLCASATSAIDVGAQLAGAGVCRTVRVATGPVPGARVV 300 Query: 317 PAP 319 AP Sbjct: 301 HAP 303 >tr|D5PX33|D5PX33_COREQ Tax_Id=525370 (ispE)SubName: Full=4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; EC=2.7.1.148;[Rhodococcus equi ATCC 33707] Length = 311 Score = 365 bits (936), Expect = 6e-99 Identities = 193/297 (64%), Positives = 224/297 (75%), Gaps = 2/297 (0%) Query: 20 VTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLP 79 VTVR P KVNL+LSVGDLR+DGYH+L TVF A+SL D+V+V +D LS+R+ GEGAES+P Sbjct: 9 VTVRAPSKVNLHLSVGDLREDGYHELRTVFQALSLADDVSVIASDALSVRVRGEGAESVP 68 Query: 80 ADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWELGV 139 D NL W+AAE++A G APDVEI+I K IPV LVA+N LW LG+ Sbjct: 69 TDHTNLVWKAAEMLAAEAGIAPDVEISIVKGIPVAGGMAGGSADAAAALVALNELWRLGL 128 Query: 140 PRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTPKVF 199 R L AA+LGSDVPF+LHGGTA+G+GRGE L VL+R++FHWVLA A GLSTP VF Sbjct: 129 DRDALSVFAARLGSDVPFSLHGGTAVGTGRGEKLLPVLSRDSFHWVLALAKGGLSTPTVF 188 Query: 200 GELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRTLRA 259 ELDRLR + PR + + ++ ALASGD LA LLGNDLQ AALSL PDLRRTLRA Sbjct: 189 RELDRLRVEGDP--PRVGDVDDLMHALASGDAEALAPLLGNDLQAAALSLAPDLRRTLRA 246 Query: 260 GVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 GV AGALAGIVSGSGPTCAFLCA A AA+ VG +LSGAGVCRTVRVASGPV GA V+ Sbjct: 247 GVTAGALAGIVSGSGPTCAFLCADADAAVAVGAELSGAGVCRTVRVASGPVPGARVI 303 >tr|C1A375|C1A375_RHOE4 Tax_Id=234621 (ispE)SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; EC=2.7.1.148;[Rhodococcus erythropolis] Length = 331 Score = 363 bits (933), Expect = 1e-98 Identities = 191/297 (64%), Positives = 223/297 (75%), Gaps = 2/297 (0%) Query: 20 VTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLP 79 V VR P KVNL+L+VGDLRDDGYH+LTTVF A+SL D VTV AD L++R+IG+ A ++P Sbjct: 29 VVVRAPSKVNLHLAVGDLRDDGYHELTTVFQALSLADTVTVAPADTLTVRVIGDDAAAVP 88 Query: 80 ADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWELGV 139 D NL WRAAE++A G AP+VEI IEK IPV LVA+N+LW+L Sbjct: 89 TDRANLVWRAAEMLAAEGGVAPNVEIVIEKGIPVAGGMAGGSADAAAALVALNSLWKLDF 148 Query: 140 PRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTPKVF 199 R DL A AA+LGSDVPF+LHGGTALG+GRGE L VL R TFHWVLA A GLSTP VF Sbjct: 149 SRPDLDAFAARLGSDVPFSLHGGTALGTGRGEQLVPVLTRRTFHWVLALAKGGLSTPVVF 208 Query: 200 GELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRTLRA 259 ELD+LRA+ T R + ++ AL +GDP LA LLGNDLQ AALSL PDLRRTLRA Sbjct: 209 RELDKLRAEGTPN--RLGTADELIHALTTGDPHVLAPLLGNDLQAAALSLNPDLRRTLRA 266 Query: 260 GVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 GVEAGALAGIVSGSGPTCAFLCA A +A++V +L+GAGVCRTVRVASGPV GA ++ Sbjct: 267 GVEAGALAGIVSGSGPTCAFLCADAQSAVEVSAELAGAGVCRTVRVASGPVPGARIL 323 >tr|C3JWT9|C3JWT9_RHOER Tax_Id=596309 (ispE)SubName: Full=4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; EC=2.7.1.148;[Rhodococcus erythropolis SK121] Length = 315 Score = 359 bits (922), Expect = 2e-97 Identities = 190/298 (63%), Positives = 224/298 (75%), Gaps = 4/298 (1%) Query: 20 VTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLP 79 V VR P KVNL+L+VGDLRDDGYH+LTTVF A+SL D +TV AD L++R+IG+ A ++P Sbjct: 13 VVVRAPSKVNLHLAVGDLRDDGYHELTTVFQALSLADTLTVTPADTLTVRVIGDDAAAVP 72 Query: 80 ADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWELGV 139 D NL WRAAE++A G AP+VEI IEK IPV LVA+N LW+L Sbjct: 73 TDRTNLVWRAAEMLAVEGGVAPNVEIVIEKGIPVAGGMAGGSADAAAALVALNALWKLDF 132 Query: 140 PRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTPKVF 199 R DL A AA+LGSDVPF+LHGGTALG+GRGE L VL R+TFHWVLA A GLSTP VF Sbjct: 133 SRPDLDAFAARLGSDVPFSLHGGTALGTGRGEQLVPVLTRHTFHWVLALAKGGLSTPVVF 192 Query: 200 GELDRLRADTTRGLP-RTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRTLR 258 ELD+LRA+ G P R + ++ AL +GD LA+LLGNDLQ AALSL PDLRRTLR Sbjct: 193 RELDKLRAE---GSPKRVGSADALIQALTTGDAHLLASLLGNDLQAAALSLNPDLRRTLR 249 Query: 259 AGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 AGVEAGALAGIVSGSGPTCAFLCA A +A++V +L+GAGVCRTVRVASGPV GA ++ Sbjct: 250 AGVEAGALAGIVSGSGPTCAFLCADAQSAVEVSAELAGAGVCRTVRVASGPVPGARIL 307 >sp|Q5YPY8|ISPE_NOCFA Tax_Id=37329 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Nocardia farcinica] Length = 307 Score = 357 bits (917), Expect = 9e-97 Identities = 189/306 (61%), Positives = 223/306 (72%), Gaps = 2/306 (0%) Query: 15 VTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEG 74 V V VR P KVNL+L VGDLR DGYHDLTTVF A+SL D++ + A L++++ GEG Sbjct: 4 VVPSPVLVRAPSKVNLHLGVGDLRPDGYHDLTTVFQALSLGDDLRISPASALTVKVNGEG 63 Query: 75 AESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTL 134 A +P D NL W+AA +A VGRAP VEI I+K IPV LV +N L Sbjct: 64 AAEVPTDRTNLVWKAAVRLAHLVGRAPLVEIVIDKGIPVAGGMAGGSADAAAALVGLNEL 123 Query: 135 WELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLS 194 W++G+ R +L ALAA+LGSDVPFALHGGTALG+GRGE L VL+RNTFHWVLAFA GLS Sbjct: 124 WDMGLGRDELSALAAELGSDVPFALHGGTALGTGRGERLLPVLSRNTFHWVLAFAKGGLS 183 Query: 195 TPKVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLR 254 TP VF ELDRLR PR +P+ ++ ALASGDPA+LA LLGNDLQ AA+SL P+LR Sbjct: 184 TPAVFAELDRLREHGDP--PRLGDPQALMQALASGDPAQLAPLLGNDLQAAAVSLKPELR 241 Query: 255 RTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAH 314 RTLRAGV AGALAG+VSGSGPTCAFLC SA AA+ V +L+GAGV R+VR ASGPV GA Sbjct: 242 RTLRAGVTAGALAGLVSGSGPTCAFLCESADAAVAVAAELAGAGVARSVRTASGPVPGAR 301 Query: 315 VVPAPS 320 V+ S Sbjct: 302 VIDPES 307 >tr|C1AXZ7|C1AXZ7_RHOOB Tax_Id=632772 (ispE)SubName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; EC=2.7.1.148;[Rhodococcus opacus] Length = 311 Score = 355 bits (911), Expect = 4e-96 Identities = 187/297 (62%), Positives = 219/297 (73%), Gaps = 2/297 (0%) Query: 20 VTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLP 79 V VR P KVNL+L+VGDLRDDGYH+L TVF A+SL D V+V A+ LS+++ GE A +P Sbjct: 9 VVVRAPSKVNLHLAVGDLRDDGYHELKTVFQALSLGDTVSVVPAETLSVKVRGEDARVVP 68 Query: 80 ADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWELGV 139 D RNL W+AAE++A GR PDVEI I+K IPV LV +N LW+L + Sbjct: 69 TDSRNLVWQAAEMLAAESGRRPDVEIAIDKGIPVAGGMAGGSADAAATLVGLNALWQLDL 128 Query: 140 PRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTPKVF 199 R +L AA+LGSDVPF+LHGGTA+G+GRGE L VL+R+TFHWVLA A GLSTP VF Sbjct: 129 SREELDGFAAKLGSDVPFSLHGGTAVGTGRGERLLPVLSRSTFHWVLALAKGGLSTPTVF 188 Query: 200 GELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRTLRA 259 ELDRLRAD PR PE ++ AL +GD A LA LLGNDLQ AALSL P LRRTLRA Sbjct: 189 RELDRLRADGNP--PRLGGPEDLMHALTTGDAATLAPLLGNDLQSAALSLNPGLRRTLRA 246 Query: 260 GVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 GV AGALAGIVSGSGPTCAFLCA A AA+ V +L+GAGVCRTVRVASGPV GA ++ Sbjct: 247 GVAAGALAGIVSGSGPTCAFLCADADAAVRVSAELAGAGVCRTVRVASGPVPGARII 303 >sp|Q0S4S3|ISPE_RHOSR Tax_Id=101510 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Rhodococcus sp.] Length = 311 Score = 353 bits (906), Expect = 2e-95 Identities = 186/297 (62%), Positives = 217/297 (73%), Gaps = 2/297 (0%) Query: 20 VTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLP 79 V VR P KVNL+L+VGDLRDDGYH+L TVF A+SL D V+V A+ LS+ + GE A +P Sbjct: 9 VVVRAPSKVNLHLAVGDLRDDGYHELNTVFQALSLSDTVSVAPAETLSVTVRGEDARVVP 68 Query: 80 ADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWELGV 139 D NL W+AAE++A GR PDVEI I+K IPV LV +N LW+L + Sbjct: 69 TDSSNLVWQAAEMLAAESGRRPDVEIAIDKGIPVAGGMAGGSADAAATLVGLNALWQLDL 128 Query: 140 PRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTPKVF 199 R +L AA+LGSDVPF+LHGGTA+G+GRGE L VL+R+TFHWVLA A GLSTP VF Sbjct: 129 SREELDGFAAKLGSDVPFSLHGGTAVGTGRGERLLPVLSRSTFHWVLALAKVGLSTPTVF 188 Query: 200 GELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRTLRA 259 ELDRLRAD PR PE ++ AL +GD A LA LLGNDLQ AALSL P LRRTLRA Sbjct: 189 RELDRLRADGNP--PRLGGPEDLMHALTTGDAATLAPLLGNDLQSAALSLNPGLRRTLRA 246 Query: 260 GVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 GV AGALAGIVSGSGPTCAFLCA A AA+ V +L+GAGVCRTVRVASGPV GA ++ Sbjct: 247 GVAAGALAGIVSGSGPTCAFLCAEADAAVRVSAELAGAGVCRTVRVASGPVPGARII 303 >sp|A4F7X3|ISPE_SACEN Tax_Id=405948 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148; AltName: Full=4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase;[Saccharopolyspora erythraea] Length = 318 Score = 348 bits (893), Expect = 5e-94 Identities = 185/300 (61%), Positives = 216/300 (72%), Gaps = 5/300 (1%) Query: 20 VTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLP 79 +TVRVP KVNL+LSVGD R+DGYH+L TVF A+S+ DEVTV AD + + GEGA+S+P Sbjct: 6 ITVRVPAKVNLHLSVGDTREDGYHELVTVFQALSMTDEVTVHIADEPGIEVRGEGADSVP 65 Query: 80 ADERNLAWRAAELMAEHVGRAPD---VEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 NLAW+A +AE GR PD V ++I K IPV L+A+N LW Sbjct: 66 TGPSNLAWKAVRALAERCGRDPDEPGVRVSINKGIPVAGGMAGGSADAAAALLALNHLWR 125 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L + R +L +AA +GSDVPFAL GGTALG+GRGE L VLAR+TFHWV+A RGL TP Sbjct: 126 LEMGRDELAGIAADIGSDVPFALQGGTALGTGRGEQLIPVLARHTFHWVIALDRRGLETP 185 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 VF ELDRLR ++ R E EPVL ALASGDP +LA LLGNDLQ AA+SL P LRRT Sbjct: 186 GVFSELDRLREESRPN--RVGEVEPVLEALASGDPRQLALLLGNDLQAAAVSLRPGLRRT 243 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGV+AGALAGIVSGSGPTCAFLC A AA+ V +LSGAGVCRTVRVA GPV GA +V Sbjct: 244 LRAGVQAGALAGIVSGSGPTCAFLCTDADAAVRVAAELSGAGVCRTVRVAQGPVPGARLV 303 >tr|C7MZI6|C7MZI6_SACVD Tax_Id=471857 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Saccharomonospora viridis] Length = 308 Score = 343 bits (881), Expect = 1e-92 Identities = 187/299 (62%), Positives = 215/299 (71%), Gaps = 5/299 (1%) Query: 20 VTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLP 79 VTVRVP K+NL+LSVGD+RDDGYH+LTTVF A+SL DEVT + + GEGA S+P Sbjct: 9 VTVRVPSKINLHLSVGDVRDDGYHELTTVFQALSLTDEVTALAGGDSGVEVSGEGARSVP 68 Query: 80 ADERNLAWRAAELMAEHVGR---APDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 +E NLA RA +AEHVGR A V + I K IPV L+A + LW Sbjct: 69 KNEDNLAVRAVRALAEHVGRPERAERVRLVIRKGIPVAGGMAGGSADAAGALLACSILWG 128 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L + R +L +AA LGSDVPFAL+GGTALG+GRGE L VL+R+TFHWVLAF RGLSTP Sbjct: 129 LDLHRDELAEVAATLGSDVPFALYGGTALGTGRGEQLVPVLSRHTFHWVLAFDQRGLSTP 188 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 KV+GELDRLR PR PE +L ALASGDP LA LLGNDLQ AA+SL P LRRT Sbjct: 189 KVYGELDRLRE--AGDPPRVGAPEALLEALASGDPHRLAPLLGNDLQAAAISLRPGLRRT 246 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHV 315 LRAGV AGALAG+VSGSGPTCAFLC+ A +AL V +L+GAGVCRTVRVA GPV GA V Sbjct: 247 LRAGVTAGALAGVVSGSGPTCAFLCSDADSALKVAAELAGAGVCRTVRVAHGPVPGARV 305 >tr|C6WJI0|C6WJI0_ACTMD Tax_Id=446462 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Actinosynnema mirum] Length = 321 Score = 343 bits (880), Expect = 2e-92 Identities = 182/302 (60%), Positives = 218/302 (72%), Gaps = 5/302 (1%) Query: 20 VTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESLP 79 VTVRVP KVNL+L+VGDLRDDGYHDL T+F A+SL DEVTV +D + + GEGAES+P Sbjct: 9 VTVRVPAKVNLHLAVGDLRDDGYHDLVTIFQALSLTDEVTVGASDDPGVEVRGEGAESVP 68 Query: 80 ADERNLAWRAAELMAEHVGRAPD---VEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 D NLAW+A ++AEH GR P+ V + I K+IPV LVA+ LW+ Sbjct: 69 TDPSNLAWKAVRVLAEHTGRDPEDVKVRVGIRKAIPVAGGMAGGSADAAATLVALAALWK 128 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 L R +L LA ++G+DVPFAL+GGTALG+ RG+ L VL ++ FHWVLAF +GLSTP Sbjct: 129 LDTTRDELAELAGRIGADVPFALYGGTALGTDRGDRLVPVLGKHPFHWVLAFDKQGLSTP 188 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 +VF ELDRLRA+ PR E E VL L+SGDP +LA LLGNDLQ AA+SL P+LRRT Sbjct: 189 EVFRELDRLRAEGNP--PRVGEAEAVLEGLSSGDPRQLALLLGNDLQAAAVSLRPNLRRT 246 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 LRAGV AGALAG+VSGSGPTCAFLC A+ V +L+GAGVCRTVRVA GPV GA VV Sbjct: 247 LRAGVNAGALAGMVSGSGPTCAFLCEDGDTAVRVAAELAGAGVCRTVRVAQGPVPGARVV 306 Query: 317 PA 318 A Sbjct: 307 GA 308 >tr|D5UVN4|D5UVN4_TSUPA Tax_Id=521096 SubName: Full=4-diphosphocytidyl-2C-methyl-D- erythritolkinase;[Tsukamurella paurometabola DSM 20162] Length = 301 Score = 334 bits (856), Expect = 1e-89 Identities = 178/298 (59%), Positives = 209/298 (70%), Gaps = 2/298 (0%) Query: 19 SVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAESL 78 S+TVR P KVNL+L VGD+R DG+H+L TVF A+SL DEV++ AD LSL + GEGA + Sbjct: 5 SLTVRAPAKVNLHLGVGDVRPDGFHELQTVFQALSLHDEVSLARADELSLHVSGEGARDV 64 Query: 79 PADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWELG 138 P D NLA RA +AE G P V I I K IPV L+ TLW L Sbjct: 65 PTDSTNLAARAVAALAERYGLDPAVRIEIAKGIPVAGGMAGGSADAAAALLGAATLWHLD 124 Query: 139 VPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTPKV 198 + R +L +AA LGSDVPF+LHGGTALG+GRGE L L+R FHW LA A GLSTP V Sbjct: 125 LSRSELDEIAATLGSDVPFSLHGGTALGTGRGEQLIPALSRGEFHWTLALAREGLSTPAV 184 Query: 199 FGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRTLR 258 + ELDRLR PR P+ +LAA+ASGDP LA LL NDLQ AALSL P LRRTLR Sbjct: 185 YRELDRLR--EAGDPPRAGSPDDLLAAVASGDPNRLAPLLANDLQAAALSLQPGLRRTLR 242 Query: 259 AGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 AG+EAGALAGIVSGSGPTCAFLC + +A++VG++L+GAGVCRTVRVASGPV GA V+ Sbjct: 243 AGMEAGALAGIVSGSGPTCAFLCINGESAVEVGSELAGAGVCRTVRVASGPVPGAEVL 300 >tr|D0L708|D0L708_GORB4 Tax_Id=526226 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Gordonia bronchialis] Length = 315 Score = 320 bits (820), Expect = 2e-85 Identities = 176/311 (56%), Positives = 211/311 (67%), Gaps = 3/311 (0%) Query: 9 STASEWVTTGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSL 68 S AS V + SVT R P KVNL+L VG R DGYHDL TVF A+SL D+V V L++ Sbjct: 2 SPASLSVVSDSVTARAPSKVNLHLGVGPRRPDGYHDLVTVFQALSLHDDVRVSPGTDLTV 61 Query: 69 RMIGEGAESLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVL 128 + GEGA ++P D NLA RA + +AE GR+P I I+KSIPV L Sbjct: 62 SVRGEGASAVPDDSSNLAARAVQALAEWCGRSPVAAIDIDKSIPVAGGMAGGSADAAAAL 121 Query: 129 VAMNTLWELGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAF 188 VA +W+L V R DL +AA LGSDVPFALHG TALG+GRGE L +VL+R FHWVLA Sbjct: 122 VAAAAMWKLDVDRDDLSDIAAGLGSDVPFALHGATALGTGRGEQLISVLSRGEFHWVLAL 181 Query: 189 AHRGLSTPKVFGELDRLRADTTRGLPRTD---EPEPVLAALASGDPAELAALLGNDLQPA 245 A GLSTP+V+ ELDRLR + + D P+ ++ ALA+GDP +A LL NDLQPA Sbjct: 182 AREGLSTPQVYAELDRLRDNRSDDAMTDDPLRRPDDLMQALAAGDPRAVAPLLHNDLQPA 241 Query: 246 ALSLYPDLRRTLRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRV 305 ALSL P LRRTLRAGV+AGAL GIVSGSGPTCAFLC +A++V +LSGAGV R+VR Sbjct: 242 ALSLQPALRRTLRAGVDAGALNGIVSGSGPTCAFLCLDEGSAVNVAAELSGAGVARSVRT 301 Query: 306 ASGPVHGAHVV 316 ASGPV G V+ Sbjct: 302 ASGPVPGTRVI 312 >tr|C7PYX1|C7PYX1_CATAD Tax_Id=479433 (ispE)RecName: Full=4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Short=CMK; EC=2.7.1.148;[Catenulispora acidiphila] Length = 316 Score = 313 bits (803), Expect = 1e-83 Identities = 172/300 (57%), Positives = 193/300 (64%) Query: 17 TGSVTVRVPGKVNLYLSVGDLRDDGYHDLTTVFHAVSLLDEVTVRNADVLSLRMIGEGAE 76 T SVTVRVP KVNL LSVG LR DGYHDL TVFHAV L DEV AD L++ GEG Sbjct: 17 TESVTVRVPAKVNLALSVGPLRSDGYHDLATVFHAVGLFDEVNAAAADTLAVTCEGEGQV 76 Query: 77 SLPADERNLAWRAAELMAEHVGRAPDVEITIEKSIPVXXXXXXXXXXXXXVLVAMNTLWE 136 +P D+ NLAWRAAEL+A VGR+P V + + K IPV LVA + LW Sbjct: 77 EVPLDDTNLAWRAAELLARTVGRSPGVRLHLTKGIPVAGGMAGGSADAAGALVACDALWG 136 Query: 137 LGVPRRDLHALAAQLGSDVPFALHGGTALGSGRGEDLATVLARNTFHWVLAFAHRGLSTP 196 G+ R DLH LAAQLGSDVPFALHGGTA+G+GRGE + VLAR FHWV AFAH GLSTP Sbjct: 137 TGLSRDDLHVLAAQLGSDVPFALHGGTAMGTGRGEQITPVLARGEFHWVFAFAHDGLSTP 196 Query: 197 KVFGELDRLRADTTRGLPRTDEPEPVLAALASGDPAELAALLGNDLQPAALSLYPDLRRT 256 VF ELDRLR + +L AL +GD L A L NDL A SL PDLR T Sbjct: 197 AVFHELDRLREAAGEEATAPGVEDELLRALRAGDSTLLGAALRNDLTRPATSLRPDLRAT 256 Query: 257 LRAGVEAGALAGIVSGSGPTCAFLCASAPAALDVGTQLSGAGVCRTVRVASGPVHGAHVV 316 L+AG EAGAL ++SGSGPTCAFL A A AA V L A R VR A GP GAH++ Sbjct: 257 LQAGREAGALGTLLSGSGPTCAFLAADAVAAATVAAALEAAPSVRAVRRALGPAAGAHLL 316 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.317 0.133 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 2,648,756,032 Number of extensions: 111966404 Number of successful extensions: 324061 Number of sequences better than 10.0: 2388 Number of HSP's gapped: 323189 Number of HSP's successfully gapped: 2405 Length of query: 322 Length of database: 4,236,830,644 Length adjustment: 138 Effective length of query: 184 Effective length of database: 2,510,745,412 Effective search space: 461977155808 Effective search space used: 461977155808 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 81 (35.8 bits)