BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MSMEG_5937 (349 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 12,507,864 sequences; 4,236,830,644 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|A0R4S6|HOA2_MYCS2 Tax_Id=246196 RecName: Full=4-hydroxy-2-oxo... 655 0.0 sp|A4T7U4|HOA_MYCGI Tax_Id=350054 RecName: Full=4-hydroxy-2-oxov... 629 e-178 sp|Q743Q8|HOA_MYCPA Tax_Id=1770 RecName: Full=4-hydroxy-2-oxoval... 628 e-178 sp|A3Q6M9|HOA2_MYCSJ Tax_Id=164757 RecName: Full=4-hydroxy-2-oxo... 627 e-178 sp|A0QAG9|HOA_MYCA1 Tax_Id=243243 RecName: Full=4-hydroxy-2-oxov... 626 e-177 sp|Q1B2X1|HOA1_MYCSS Tax_Id=164756 RecName: Full=4-hydroxy-2-oxo... 626 e-177 sp|A1UM80|HOA1_MYCSK Tax_Id=189918 RecName: Full=4-hydroxy-2-oxo... 626 e-177 sp|A1TFQ5|HOA3_MYCVP Tax_Id=350058 RecName: Full=4-hydroxy-2-oxo... 624 e-177 sp|A3Q4B9|HOA1_MYCSJ Tax_Id=164757 RecName: Full=4-hydroxy-2-oxo... 624 e-177 tr|D5P8G8|D5P8G8_9MYCO Tax_Id=525368 (mhpE)SubName: Full=4-hydro... 618 e-175 sp|B2HI25|HOA2_MYCMM Tax_Id=216594 RecName: Full=4-hydroxy-2-oxo... 599 e-169 sp|A0PUX2|HOA2_MYCUA Tax_Id=362242 RecName: Full=4-hydroxy-2-oxo... 594 e-168 sp|B1MH40|HOA1_MYCA9 Tax_Id=561007 RecName: Full=4-hydroxy-2-oxo... 590 e-167 sp|P71867|HOA_MYCTU Tax_Id=1773 RecName: Full=4-hydroxy-2-oxoval... 587 e-166 sp|A5U8K8|HOA_MYCTA Tax_Id=419947 (bphI)RecName: Full=4-hydroxy-... 587 e-166 sp|C1AHZ2|HOA_MYCBT Tax_Id=561275 RecName: Full=4-hydroxy-2-oxov... 587 e-166 sp|A1KPL9|HOA_MYCBP Tax_Id=410289 RecName: Full=4-hydroxy-2-oxov... 587 e-166 sp|Q7TW97|HOA_MYCBO Tax_Id=1765 RecName: Full=4-hydroxy-2-oxoval... 587 e-166 tr|C6DM51|C6DM51_MYCTK Tax_Id=478434 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|A5WTA3|A5WTA3_MYCTF Tax_Id=336982 SubName: Full=Hypothetical ... 587 e-166 tr|D6G494|D6G494_MYCTU Tax_Id=478435 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|D6FT16|D6FT16_MYCTU Tax_Id=611304 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|D6FHE2|D6FHE2_MYCTU Tax_Id=611303 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|D6EYM3|D6EYM3_MYCTU Tax_Id=611302 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|D5ZAA7|D5ZAA7_MYCTU Tax_Id=537209 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|D5YXF5|D5YXF5_MYCTU Tax_Id=515616 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|D5YKY4|D5YKY4_MYCTU Tax_Id=520140 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|D5Y9D2|D5Y9D2_MYCTU Tax_Id=520141 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|D5XZM3|D5XZM3_MYCTU Tax_Id=515617 SubName: Full=4-hydroxy-2-o... 587 e-166 tr|A2VPU6|A2VPU6_MYCTU Tax_Id=348776 SubName: Full=Putative unch... 587 e-166 tr|A4KM21|A4KM21_MYCTU Tax_Id=395095 SubName: Full=Hypothetical ... 586 e-165 tr|C6GCU5|C6GCU5_9NOCA Tax_Id=1830 (hsaF)SubName: Full=HsaF;[Rho... 552 e-155 sp|C0ZPX1|HOA1_RHOE4 Tax_Id=234621 RecName: Full=4-hydroxy-2-oxo... 538 e-151 sp|Q0S815|HOA3_RHOSR Tax_Id=101510 (hsaF)RecName: Full=4-hydroxy... 536 e-150 tr|C3JUT2|C3JUT2_RHOER Tax_Id=596309 (dmpG)SubName: Full=4-hydro... 535 e-150 sp|C1BAJ4|HOA3_RHOOB Tax_Id=632772 RecName: Full=4-hydroxy-2-oxo... 533 e-149 sp|Q5Z2N2|HOA1_NOCFA Tax_Id=37329 RecName: Full=4-hydroxy-2-oxov... 525 e-147 tr|C5II23|C5II23_9NOCA Tax_Id=646677 SubName: Full=4-hydroxy-2-o... 522 e-146 tr|D0L3M4|D0L3M4_GORB4 Tax_Id=526226 SubName: Full=4-hydroxy-2-o... 505 e-141 tr|D1AB65|D1AB65_THECD Tax_Id=471852 SubName: Full=4-hydroxy-2-o... 490 e-136 tr|D4SHM7|D4SHM7_9ACTO Tax_Id=585531 (mhpE)SubName: Full=4-hydro... 486 e-135 sp|C1AYB4|HOA5_RHOOB Tax_Id=632772 RecName: Full=4-hydroxy-2-oxo... 479 e-133 sp|Q0S4F8|HOA4_RHOSR Tax_Id=101510 RecName: Full=4-hydroxy-2-oxo... 475 e-132 tr|D3F7A6|D3F7A6_CONWI Tax_Id=469383 SubName: Full=4-hydroxy-2-o... 437 e-121 tr|D5UYS5|D5UYS5_TSUPA Tax_Id=521096 SubName: Full=4-hydroxy-2-o... 414 e-113 >sp|A0R4S6|HOA2_MYCS2 Tax_Id=246196 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;[Mycobacterium smegmatis] Length = 349 Score = 655 bits (1689), Expect = 0.0 Identities = 334/349 (95%), Positives = 334/349 (95%) Query: 1 MSDIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGG 60 MSDIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGG Sbjct: 1 MSDIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGG 60 Query: 61 SSFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCT 120 SSFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCT Sbjct: 61 SSFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCT 120 Query: 121 EADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVL 180 EADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVL Sbjct: 121 EADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVL 180 Query: 181 EGVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNA 240 EGVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNA Sbjct: 181 EGVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNA 240 Query: 241 PVEALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKH 300 PVEALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKH Sbjct: 241 PVEALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKH 300 Query: 301 AIRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAASK 349 AIRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAASK Sbjct: 301 AIRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAASK 349 >sp|A4T7U4|HOA_MYCGI Tax_Id=350054 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium gilvum] Length = 352 Score = 629 bits (1623), Expect = e-178 Identities = 318/347 (91%), Positives = 326/347 (93%) Query: 3 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSS 62 DI+FNPIWDVRMTDTSLRDGSHHKRHQFT +EV SIVAALDAAGVPVIEVTHGDGLGGSS Sbjct: 5 DIYFNPIWDVRMTDTSLRDGSHHKRHQFTKDEVGSIVAALDAAGVPVIEVTHGDGLGGSS 64 Query: 63 FNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 122 FNYGFSKTPEQELIK+AAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA Sbjct: 65 FNYGFSKTPEQELIKLAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 124 Query: 123 DVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 182 DVSIQHFGLARELGLETVGFLMM+HTISPEKLA+QARIMADAGCQCVYVVDSAGALVLEG Sbjct: 125 DVSIQHFGLARELGLETVGFLMMSHTISPEKLAKQARIMADAGCQCVYVVDSAGALVLEG 184 Query: 183 VRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 242 V DRV ALVAELG DAQVGFHGHENLGLGVANS+EAVRAGAKQIDGSCRRFGAGAGNAPV Sbjct: 185 VADRVSALVAELGDDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSCRRFGAGAGNAPV 244 Query: 243 EALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAI 302 EALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHAI Sbjct: 245 EALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAI 304 Query: 303 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAASK 349 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEA A++ Sbjct: 305 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAEATR 351 >sp|Q743Q8|HOA_MYCPA Tax_Id=1770 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium paratuberculosis] Length = 352 Score = 628 bits (1619), Expect = e-178 Identities = 316/347 (91%), Positives = 327/347 (94%) Query: 2 SDIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGS 61 +DIFFNPIWDVR+TDTSLRDGSHHKRHQFT +EV++IVAALDAAGVPVIEVTHGDGLGGS Sbjct: 3 TDIFFNPIWDVRLTDTSLRDGSHHKRHQFTKDEVQAIVAALDAAGVPVIEVTHGDGLGGS 62 Query: 62 SFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE 121 SFNYGFSKTPEQELIK+AAETAK++KIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE Sbjct: 63 SFNYGFSKTPEQELIKLAAETAKDAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE 122 Query: 122 ADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLE 181 ADVSIQHFGLARELGLETVGFLMM+HTI PEKLAQQARIMADAGCQCVYVVDSAGALVLE Sbjct: 123 ADVSIQHFGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLE 182 Query: 182 GVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP 241 GVRDRV ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP Sbjct: 183 GVRDRVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP 242 Query: 242 VEALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHA 301 VEALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA Sbjct: 243 VEALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHA 302 Query: 302 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE+ A+ Sbjct: 303 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGAA 349 >sp|A3Q6M9|HOA2_MYCSJ Tax_Id=164757 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;[Mycobacterium sp.] Length = 353 Score = 627 bits (1618), Expect = e-178 Identities = 317/346 (91%), Positives = 325/346 (93%) Query: 3 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSS 62 DIFFNPIWDVRMTDTSLRDGSHHKRHQFT +EV +IVAALD AGVPVIEVTHGDGLGGSS Sbjct: 5 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSS 64 Query: 63 FNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 122 FNYGFSKTPEQELIK+AAETAKE+KIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA Sbjct: 65 FNYGFSKTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 124 Query: 123 DVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 182 DVSIQHFGLARELGLETVGFLMM+HTI PEKLAQQARIMADAGCQCVYVVDSAGALVLEG Sbjct: 125 DVSIQHFGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 184 Query: 183 VRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 242 VRDRV ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV Sbjct: 185 VRDRVAALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 244 Query: 243 EALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAI 302 EALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHAI Sbjct: 245 EALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAI 304 Query: 303 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ++ A+ Sbjct: 305 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGAT 350 >sp|A0QAG9|HOA_MYCA1 Tax_Id=243243 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium avium] Length = 352 Score = 626 bits (1615), Expect = e-177 Identities = 315/347 (90%), Positives = 326/347 (93%) Query: 2 SDIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGS 61 +DIFFNP+WDVR+TDTSLRDGSHHKRHQFT +EV++IVAALD AGVPVIEVTHGDGLGGS Sbjct: 3 TDIFFNPMWDVRLTDTSLRDGSHHKRHQFTKDEVQAIVAALDVAGVPVIEVTHGDGLGGS 62 Query: 62 SFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE 121 SFNYGFSKTPEQELIK+AAETAKE+KIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE Sbjct: 63 SFNYGFSKTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE 122 Query: 122 ADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLE 181 ADVSIQHFGLARELGLETVGFLMM+HTI PEKLAQQARIMADAGCQCVYVVDSAGALVLE Sbjct: 123 ADVSIQHFGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLE 182 Query: 182 GVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP 241 GVRDRV ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP Sbjct: 183 GVRDRVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP 242 Query: 242 VEALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHA 301 VEALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA Sbjct: 243 VEALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHA 302 Query: 302 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE+ A+ Sbjct: 303 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGAA 349 >sp|Q1B2X1|HOA1_MYCSS Tax_Id=164756 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Mycobacterium sp.] Length = 353 Score = 626 bits (1614), Expect = e-177 Identities = 316/346 (91%), Positives = 324/346 (93%) Query: 3 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSS 62 DIFFNPIWDVRMTDTSLRDGSHHKRHQFT +EV +IVAALD AGVPVIEVTHGDGLGGSS Sbjct: 5 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSS 64 Query: 63 FNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 122 FNYGFSKTPEQELIK+AAETAKE+KIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA Sbjct: 65 FNYGFSKTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 124 Query: 123 DVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 182 DVSIQHFGLARELGLETVGFLMM+HTI PEKLAQQARIMADAGCQCVYVVDSAGALVLEG Sbjct: 125 DVSIQHFGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 184 Query: 183 VRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 242 VRDRV ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV Sbjct: 185 VRDRVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 244 Query: 243 EALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAI 302 EALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHAI Sbjct: 245 EALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAI 304 Query: 303 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ++ A+ Sbjct: 305 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGAT 350 >sp|A1UM80|HOA1_MYCSK Tax_Id=189918 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Mycobacterium sp.] Length = 353 Score = 626 bits (1614), Expect = e-177 Identities = 316/346 (91%), Positives = 324/346 (93%) Query: 3 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSS 62 DIFFNPIWDVRMTDTSLRDGSHHKRHQFT +EV +IVAALD AGVPVIEVTHGDGLGGSS Sbjct: 5 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSS 64 Query: 63 FNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 122 FNYGFSKTPEQELIK+AAETAKE+KIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA Sbjct: 65 FNYGFSKTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 124 Query: 123 DVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 182 DVSIQHFGLARELGLETVGFLMM+HTI PEKLAQQARIMADAGCQCVYVVDSAGALVLEG Sbjct: 125 DVSIQHFGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 184 Query: 183 VRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 242 VRDRV ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV Sbjct: 185 VRDRVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 244 Query: 243 EALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAI 302 EALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHAI Sbjct: 245 EALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAI 304 Query: 303 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ++ A+ Sbjct: 305 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGAT 350 >sp|A1TFQ5|HOA3_MYCVP Tax_Id=350058 RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;[Mycobacterium vanbaalenii] Length = 350 Score = 624 bits (1609), Expect = e-177 Identities = 315/346 (91%), Positives = 325/346 (93%) Query: 3 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSS 62 +I+FNPIWDVRMTDTSLRDGSHHKRHQFT +EV++IVAALDAAGVPVIEVTHGDGLGGSS Sbjct: 5 EIYFNPIWDVRMTDTSLRDGSHHKRHQFTKDEVQAIVAALDAAGVPVIEVTHGDGLGGSS 64 Query: 63 FNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 122 FNYGFSKTPEQELIK+AAETAKESKIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEA Sbjct: 65 FNYGFSKTPEQELIKLAAETAKESKIAFLMLPGVGTKEDIKEAQSNGGSICRIATHCTEA 124 Query: 123 DVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 182 DVSIQHFGLARELGLETVGFLMM+HTI PEKLA+QARIMADAGCQCVYVVDSAGALVLEG Sbjct: 125 DVSIQHFGLARELGLETVGFLMMSHTIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEG 184 Query: 183 VRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 242 V DRV ALVAELGSDAQVGFHGHENLGLGVANS+EAVRAGAKQIDGSCRRFGAGAGNAPV Sbjct: 185 VADRVAALVAELGSDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSCRRFGAGAGNAPV 244 Query: 243 EALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAI 302 EALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHAI Sbjct: 245 EALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAI 304 Query: 303 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE A S Sbjct: 305 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQETAKS 350 >sp|A3Q4B9|HOA1_MYCSJ Tax_Id=164757 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Mycobacterium sp.] Length = 363 Score = 624 bits (1609), Expect = e-177 Identities = 316/347 (91%), Positives = 324/347 (93%) Query: 2 SDIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGS 61 SDIFF+PIWDVRMTDTSLRDGSHHKRHQFT +EV +IVAALD AGVPVIEVTHGDGLGGS Sbjct: 3 SDIFFDPIWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGS 62 Query: 62 SFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE 121 SFNYGFSKTPEQELIK+AAETAKE+KIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE Sbjct: 63 SFNYGFSKTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTE 122 Query: 122 ADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLE 181 ADVSIQHFGLARELGLETVGFLMM+HTI PEKLAQQARIMADAGCQCVYVVDSAGALVLE Sbjct: 123 ADVSIQHFGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLE 182 Query: 182 GVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP 241 GVRDRV ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP Sbjct: 183 GVRDRVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAP 242 Query: 242 VEALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHA 301 VEALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA Sbjct: 243 VEALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHA 302 Query: 302 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKRE E+ A+ Sbjct: 303 IRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREMESDAA 349 >tr|D5P8G8|D5P8G8_9MYCO Tax_Id=525368 (mhpE)SubName: Full=4-hydroxy-2-oxovalerate aldolase; EC=4.1.3.39;[Mycobacterium parascrofulaceum ATCC BAA-614] Length = 353 Score = 618 bits (1594), Expect = e-175 Identities = 311/346 (89%), Positives = 323/346 (93%) Query: 3 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSS 62 +IFFNPIWDVR+TDTSLRDGSHHKRHQFT +EV +IVAALD AGVPVIEVTHGDGLGGSS Sbjct: 5 EIFFNPIWDVRLTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSS 64 Query: 63 FNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 122 FNYGFS+TPEQELIK+AA TAKE+KIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA Sbjct: 65 FNYGFSRTPEQELIKLAAATAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 124 Query: 123 DVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 182 DVSIQHFGLARELGLETVGFLMM+HTI+PEKLA QARIMADAGCQCVYVVDSAGALVLEG Sbjct: 125 DVSIQHFGLARELGLETVGFLMMSHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLEG 184 Query: 183 VRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 242 VRDRV ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV Sbjct: 185 VRDRVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 244 Query: 243 EALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAI 302 EALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHAI Sbjct: 245 EALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAI 304 Query: 303 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE+ ++ Sbjct: 305 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGSA 350 >sp|B2HI25|HOA2_MYCMM Tax_Id=216594 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;[Mycobacterium marinum] Length = 347 Score = 599 bits (1545), Expect = e-169 Identities = 304/337 (90%), Positives = 314/337 (93%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 IWDVR+TDTSLRDGSHHKRHQF EEV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA+TAKE+KIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEA 345 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE+ Sbjct: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 >sp|A0PUX2|HOA2_MYCUA Tax_Id=362242 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;[Mycobacterium ulcerans] Length = 347 Score = 594 bits (1531), Expect = e-168 Identities = 302/337 (89%), Positives = 312/337 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 IWDVR+TDTSLRDGSHHKRHQF EEV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 IWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KT EQELIK+AA+TAKE+KIAFLMLPGVGTKEDIKEAQ+NGGSICRIATHCTEADVSIQH Sbjct: 64 KTSEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 GLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 LGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVA 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSVEAVRAGAKQIDGS RRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQSERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQSERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEA 345 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQE+ Sbjct: 304 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQES 340 >sp|B1MH40|HOA1_MYCA9 Tax_Id=561007 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Mycobacterium abscessus] Length = 359 Score = 590 bits (1522), Expect = e-167 Identities = 298/342 (87%), Positives = 312/342 (91%) Query: 4 IFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSF 63 IFF+ WDVR+TDTSLRDGSHHKRHQFT +EVR+IVAALD AGVPVIEVTHGDGLGGSSF Sbjct: 15 IFFDAAWDVRVTDTSLRDGSHHKRHQFTADEVRAIVAALDGAGVPVIEVTHGDGLGGSSF 74 Query: 64 NYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEAD 123 NYGFSKTPEQELIK+AA+TA +KIAFLMLPGVGTKEDI EAQ NGGSICRIATHCTEAD Sbjct: 75 NYGFSKTPEQELIKLAAQTATNAKIAFLMLPGVGTKEDIIEAQGNGGSICRIATHCTEAD 134 Query: 124 VSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGV 183 VSIQHFGLARE GLETVGFLMM+HTISPEKLA+QARIMADAGCQCVYVVDSAGALVL+GV Sbjct: 135 VSIQHFGLARERGLETVGFLMMSHTISPEKLAKQARIMADAGCQCVYVVDSAGALVLDGV 194 Query: 184 RDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVE 243 DRV A+VAELGSDAQVGFHGHENLGLGVANS+EAVRAGAKQIDGS RRFGAGAGNAPVE Sbjct: 195 ADRVAAVVAELGSDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSTRRFGAGAGNAPVE 254 Query: 244 ALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIR 303 ALIGVFDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHAIR Sbjct: 255 ALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIR 314 Query: 304 QSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEA 345 Q ERYGVPAHQLLHRAG+RKLIGGQEDQLIDIALEI+RE A Sbjct: 315 QGERYGVPAHQLLHRAGERKLIGGQEDQLIDIALEIQRENAA 356 >sp|P71867|HOA_MYCTU Tax_Id=1773 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium tuberculosis] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >sp|A5U8K8|HOA_MYCTA Tax_Id=419947 (bphI)RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium tuberculosis] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >sp|C1AHZ2|HOA_MYCBT Tax_Id=561275 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium bovis] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >sp|A1KPL9|HOA_MYCBP Tax_Id=410289 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium bovis] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >sp|Q7TW97|HOA_MYCBO Tax_Id=1765 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase;[Mycobacterium bovis] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|C6DM51|C6DM51_MYCTK Tax_Id=478434 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|A5WTA3|A5WTA3_MYCTF Tax_Id=336982 SubName: Full=Hypothetical 4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D6G494|D6G494_MYCTU Tax_Id=478435 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis KZN 605] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D6FT16|D6FT16_MYCTU Tax_Id=611304 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis K85] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D6FHE2|D6FHE2_MYCTU Tax_Id=611303 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis CPHL_A] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D6EYM3|D6EYM3_MYCTU Tax_Id=611302 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis T46] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D5ZAA7|D5ZAA7_MYCTU Tax_Id=537209 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis GM 1503] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D5YXF5|D5YXF5_MYCTU Tax_Id=515616 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis 02_1987] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D5YKY4|D5YKY4_MYCTU Tax_Id=520140 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis EAS054] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D5Y9D2|D5Y9D2_MYCTU Tax_Id=520141 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis T85] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|D5XZM3|D5XZM3_MYCTU Tax_Id=515617 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis T92] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|A2VPU6|A2VPU6_MYCTU Tax_Id=348776 SubName: Full=Putative uncharacterized protein;[Mycobacterium tuberculosis C] Length = 346 Score = 587 bits (1514), Expect = e-166 Identities = 296/340 (87%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|A4KM21|A4KM21_MYCTU Tax_Id=395095 SubName: Full=Hypothetical 4-hydroxy-2-oxovalerate aldolase;[Mycobacterium tuberculosis str. Haarlem] Length = 346 Score = 586 bits (1511), Expect = e-165 Identities = 295/340 (86%), Positives = 313/340 (92%) Query: 9 IWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 68 +WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS Sbjct: 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63 Query: 69 KTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 128 KTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH Sbjct: 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123 Query: 129 FGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQ 188 FGLARELGLETVGFLMMAHTI+P+KLA QARIMADAGCQCVYVVDSAGALVL+GV DRV Sbjct: 124 FGLARELGLETVGFLMMAHTIAPDKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183 Query: 189 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 248 ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV Sbjct: 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243 Query: 249 FDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERY 308 FDKIGVKTGIDFFDI CLLDRNALIMGYSGVYSSFLKHA+RQ+ERY Sbjct: 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303 Query: 309 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348 GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+ Sbjct: 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343 >tr|C6GCU5|C6GCU5_9NOCA Tax_Id=1830 (hsaF)SubName: Full=HsaF;[Rhodococcus ruber] Length = 352 Score = 552 bits (1422), Expect = e-155 Identities = 274/344 (79%), Positives = 304/344 (88%) Query: 3 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSS 62 DIFF P WD+R+TDTSLRDGSHHKRHQF EEVR++VAALD +GVPVIEVTHGDGLGGSS Sbjct: 9 DIFFEPSWDIRVTDTSLRDGSHHKRHQFDREEVRAVVAALDLSGVPVIEVTHGDGLGGSS 68 Query: 63 FNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 122 FNYGFSK PEQELIKIA +TA+ +KIAFLMLPGVG KEDI EAQ+NG SICRIATHCTEA Sbjct: 69 FNYGFSKVPEQELIKIAVDTAQHAKIAFLMLPGVGIKEDIVEAQDNGASICRIATHCTEA 128 Query: 123 DVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 182 DVS+QHFGLARE GLETVGFLMMAHT++PEKLA+QARIMADAGCQCVYVVDSAGALVLE Sbjct: 129 DVSVQHFGLARERGLETVGFLMMAHTVTPEKLAEQARIMADAGCQCVYVVDSAGALVLEQ 188 Query: 183 VRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 242 V +RV+ALVAELGSDAQVGFHGHENLGLGVANS+ AVRAGA+QIDGS RRFGAGAGN PV Sbjct: 189 VTERVEALVAELGSDAQVGFHGHENLGLGVANSIAAVRAGARQIDGSARRFGAGAGNTPV 248 Query: 243 EALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAI 302 EA +GV DK+G+KTGIDFF I CLLDR AL+MGY+GVYSSFL+HA Sbjct: 249 EAFVGVCDKVGIKTGIDFFAIADAAEDVVRPVMPAECLLDRQALMMGYAGVYSSFLRHAE 308 Query: 303 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAA 346 RQ+ERYGV A +LL RAG+RKLIGGQEDQLIDIALE++REQ++A Sbjct: 309 RQAERYGVSAAELLVRAGKRKLIGGQEDQLIDIALELQREQQSA 352 >sp|C0ZPX1|HOA1_RHOE4 Tax_Id=234621 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Rhodococcus erythropolis] Length = 347 Score = 538 bits (1387), Expect = e-151 Identities = 276/347 (79%), Positives = 300/347 (86%), Gaps = 1/347 (0%) Query: 1 MSD-IFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLG 59 MSD I F+ WD+R+TDTSLRDGSHHKRHQFT EEVR+IV ALD AGVPVIEVTHGDGLG Sbjct: 1 MSDMIHFDSSWDIRVTDTSLRDGSHHKRHQFTVEEVRAIVGALDGAGVPVIEVTHGDGLG 60 Query: 60 GSSFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHC 119 GSSFNYGFSKTPEQELIK A ETA +KIAFLMLPG+G K+DI AQ+NG SICRIATHC Sbjct: 61 GSSFNYGFSKTPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHC 120 Query: 120 TEADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALV 179 TEADVSIQHFGLARE GLETVGFLMMAH+I PEKLA+QARIMADAGCQCVYVVDSAGALV Sbjct: 121 TEADVSIQHFGLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALV 180 Query: 180 LEGVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGN 239 LE V DRV+ALV ELG+DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGN Sbjct: 181 LEQVSDRVEALVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGN 240 Query: 240 APVEALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLK 299 APVEA +GV DKIGVKTGIDFF I CLLDR AL+MGY+GVYSSFLK Sbjct: 241 APVEAFVGVCDKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLK 300 Query: 300 HAIRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAA 346 HA RQ+ERYGV + +LL RAG+RKL+GGQEDQLIDIALE++RE A+ Sbjct: 301 HAERQAERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQREAAAS 347 >sp|Q0S815|HOA3_RHOSR Tax_Id=101510 (hsaF)RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;[Rhodococcus sp.] Length = 339 Score = 536 bits (1382), Expect = e-150 Identities = 270/334 (80%), Positives = 295/334 (88%) Query: 10 WDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 69 WD+R+TDTSLRDGSHHKRHQFTGEEVR+IV ALD AGVPVIEVTHGDGLGGSSFNYGFSK Sbjct: 5 WDIRVTDTSLRDGSHHKRHQFTGEEVRAIVGALDHAGVPVIEVTHGDGLGGSSFNYGFSK 64 Query: 70 TPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHF 129 PEQELI IA +TAK +KIAFLMLPG+G K+DI AQ+NG SICRIATHCTEADVSIQHF Sbjct: 65 VPEQELISIAVDTAKNAKIAFLMLPGLGIKDDIIVAQDNGASICRIATHCTEADVSIQHF 124 Query: 130 GLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQA 189 GLAR+ GLETVGFLMMAH+I+PEKLA+QARIMADAGCQCVYVVDSAGALVLE V DRV+A Sbjct: 125 GLARDRGLETVGFLMMAHSIAPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSDRVEA 184 Query: 190 LVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 249 LV ELGSDAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEA +GV Sbjct: 185 LVQELGSDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAFVGVC 244 Query: 250 DKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYG 309 DKIGVKTGIDFF I CLLDR AL+MGY+GVYSSFLKHA RQ+ERYG Sbjct: 245 DKIGVKTGIDFFAIADAAEDVVRPAMPAECLLDRQALMMGYAGVYSSFLKHAERQAERYG 304 Query: 310 VPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQ 343 V + +LL RAG+RKL+GGQEDQLIDIALE++RE+ Sbjct: 305 VSSAELLVRAGKRKLVGGQEDQLIDIALELQRER 338 >tr|C3JUT2|C3JUT2_RHOER Tax_Id=596309 (dmpG)SubName: Full=4-hydroxy-2-oxovalerate aldolase; EC=4.1.3.-;[Rhodococcus erythropolis SK121] Length = 344 Score = 535 bits (1377), Expect = e-150 Identities = 272/343 (79%), Positives = 296/343 (86%) Query: 4 IFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSF 63 I F+ WD+R+TDTSLRDGSHHKRHQFT EVR+IV ALD AGVPVIEVTHGDGLGGSSF Sbjct: 2 IHFDSSWDIRVTDTSLRDGSHHKRHQFTVVEVRAIVGALDGAGVPVIEVTHGDGLGGSSF 61 Query: 64 NYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEAD 123 NYGFSKTPEQELIK A ETA +KIAFLMLPG+G K+DI AQ+NG SICRIATHCTEAD Sbjct: 62 NYGFSKTPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHCTEAD 121 Query: 124 VSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGV 183 VSIQHFGLARE GLETVGFLMMAH+I PEKLA+QARIMADAGCQCVYVVDSAGALVLE V Sbjct: 122 VSIQHFGLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEQV 181 Query: 184 RDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVE 243 DRV+ALV ELG+DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVE Sbjct: 182 SDRVEALVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVE 241 Query: 244 ALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIR 303 A +GV DKIGVKTGIDFF I CLLDR AL+MGY+GVYSSFLKHA R Sbjct: 242 AFVGVCDKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAER 301 Query: 304 QSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAA 346 Q+ERYGV + +LL RAG+RKL+GGQEDQLIDIALE++RE A+ Sbjct: 302 QAERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQREAAAS 344 >sp|C1BAJ4|HOA3_RHOOB Tax_Id=632772 RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;[Rhodococcus opacus] Length = 339 Score = 533 bits (1373), Expect = e-149 Identities = 267/333 (80%), Positives = 294/333 (88%) Query: 10 WDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 69 WD+R+TDTSLRDGSHHKRHQFTG+EVR+IV ALD+AGVPVIEVTHGDGLGGSSFNYGFSK Sbjct: 5 WDIRVTDTSLRDGSHHKRHQFTGDEVRAIVGALDSAGVPVIEVTHGDGLGGSSFNYGFSK 64 Query: 70 TPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHF 129 PEQELI IA +TA+ +KIAFLMLPG+G K+DI AQ+NG SICRIATHCTEADVSIQHF Sbjct: 65 VPEQELISIAVDTARNAKIAFLMLPGLGIKDDIIVAQDNGASICRIATHCTEADVSIQHF 124 Query: 130 GLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQA 189 GLAR+ GLETVGFLMMAH+I PEKLA+QARIMADAGCQCVYVVDSAGALVLE V DRV+A Sbjct: 125 GLARDRGLETVGFLMMAHSIPPEKLARQARIMADAGCQCVYVVDSAGALVLEQVSDRVEA 184 Query: 190 LVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 249 LV ELG+DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEA +GV Sbjct: 185 LVQELGADAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAFVGVC 244 Query: 250 DKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYG 309 DKIGVKTGIDFF I CLLDR AL+MGY+GVYSSFLKHA RQ+ERYG Sbjct: 245 DKIGVKTGIDFFAIADAAEDVVRPAMPAECLLDRQALMMGYAGVYSSFLKHAERQAERYG 304 Query: 310 VPAHQLLHRAGQRKLIGGQEDQLIDIALEIKRE 342 V + +LL RAG+RKL+GGQEDQLIDIALE++RE Sbjct: 305 VSSAELLVRAGKRKLVGGQEDQLIDIALELQRE 337 >sp|Q5Z2N2|HOA1_NOCFA Tax_Id=37329 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;[Nocardia farcinica] Length = 345 Score = 525 bits (1351), Expect = e-147 Identities = 263/336 (78%), Positives = 291/336 (86%) Query: 11 DVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 70 D+R+TDTSLRDGSHHKRHQFT EVR IVAALD AGVPVIEVTHGDGLGGSSFNYGFSKT Sbjct: 8 DIRVTDTSLRDGSHHKRHQFTATEVRDIVAALDGAGVPVIEVTHGDGLGGSSFNYGFSKT 67 Query: 71 PEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFG 130 PEQEL+ IAA+TAK++KIA LMLPGVG KEDIK +Q+NG SICRIATHCTEADVSIQHFG Sbjct: 68 PEQELVTIAAQTAKQAKIAVLMLPGVGVKEDIKVSQDNGASICRIATHCTEADVSIQHFG 127 Query: 131 LARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQAL 190 LARELGLETVGFLMM+HT PE LA+QARIMADAGCQCVY+VDSAGALVLE V DRV A+ Sbjct: 128 LARELGLETVGFLMMSHTQPPEVLAKQARIMADAGCQCVYIVDSAGALVLEQVSDRVAAV 187 Query: 191 VAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 250 VAELG DAQVGFHGHENL L VANS+ A+RAGA QIDGS RRFGAGAGN PVEAL+GV D Sbjct: 188 VAELGDDAQVGFHGHENLDLAVANSIYAIRAGATQIDGSARRFGAGAGNTPVEALVGVCD 247 Query: 251 KIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYGV 310 K+G++TGIDFF I CLLDR AL+MGY+GVYSSFLKHA RQ+ERYGV Sbjct: 248 KLGIRTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAERQAERYGV 307 Query: 311 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAA 346 A ++L RAG+RKL+GGQEDQLIDIALE++REQ+ A Sbjct: 308 SAAEMLVRAGRRKLVGGQEDQLIDIALELQREQQTA 343 >tr|C5II23|C5II23_9NOCA Tax_Id=646677 SubName: Full=4-hydroxy-2-oxovalerate aldolase; Flags: Fragment;[Rhodococcus sp. CECT 3014] Length = 333 Score = 522 bits (1344), Expect = e-146 Identities = 267/333 (80%), Positives = 288/333 (86%), Gaps = 1/333 (0%) Query: 1 MSD-IFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLG 59 MSD I F+ WD+R+TDTSLRDGSHHKRHQFT EEVR+IV ALD AGVPVIEVTHGDGLG Sbjct: 1 MSDMIHFDSSWDIRVTDTSLRDGSHHKRHQFTVEEVRAIVGALDGAGVPVIEVTHGDGLG 60 Query: 60 GSSFNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHC 119 GSSFNYGFSKTPEQELIK A ETA +KIAFLMLPG+G K+DI AQ+NG SICRIATHC Sbjct: 61 GSSFNYGFSKTPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHC 120 Query: 120 TEADVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALV 179 TEADVSIQHFGLARE GLETVGFLMMAH+I PEKLA+QARIMADAGCQCVYVVDSAGALV Sbjct: 121 TEADVSIQHFGLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALV 180 Query: 180 LEGVRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGN 239 LE V DRV+ALV ELG+DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGN Sbjct: 181 LEQVSDRVEALVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGN 240 Query: 240 APVEALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLK 299 APVEA +GV DKIGVKTGIDFF I CLLDR AL+MGY+GVYSSFLK Sbjct: 241 APVEAFVGVCDKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLK 300 Query: 300 HAIRQSERYGVPAHQLLHRAGQRKLIGGQEDQL 332 HA RQ+ERYGV + +LL RAG+RKL+GGQEDQL Sbjct: 301 HAERQAERYGVSSAELLVRAGKRKLVGGQEDQL 333 >tr|D0L3M4|D0L3M4_GORB4 Tax_Id=526226 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Gordonia bronchialis] Length = 358 Score = 505 bits (1301), Expect = e-141 Identities = 251/337 (74%), Positives = 286/337 (84%) Query: 11 DVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 70 D+R+TD+SLRDGSHHKRHQFT +EVRSIV ALD AGVPVIEVTHGDGLGGSSFNYGFSKT Sbjct: 20 DIRITDSSLRDGSHHKRHQFTEDEVRSIVGALDEAGVPVIEVTHGDGLGGSSFNYGFSKT 79 Query: 71 PEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFG 130 PEQ+LIK AAETAK++KIAFLMLPG+GTK+DI+ AQ+NGG ICRIATHCTEADVSIQHFG Sbjct: 80 PEQQLIKAAAETAKQAKIAFLMLPGLGTKDDIRAAQDNGGQICRIATHCTEADVSIQHFG 139 Query: 131 LARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQAL 190 LAR+LGLETVGFLMM+H+ PE LA QARIMADAGCQCVYVVDSAGALVLE V RVQAL Sbjct: 140 LARDLGLETVGFLMMSHSQPPEVLAAQARIMADAGCQCVYVVDSAGALVLEDVTVRVQAL 199 Query: 191 VAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 250 VAELG DAQVGFHGHENL + VANS+ A+RAGA+QIDGS RRFGAGAGN P EA +GV D Sbjct: 200 VAELGDDAQVGFHGHENLDIAVANSINAIRAGAQQIDGSIRRFGAGAGNTPTEAFVGVCD 259 Query: 251 KIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYGV 310 K+G+ TG+DF I CL+DR+A++MGY+G YSSFLKHA +ERYGV Sbjct: 260 KLGITTGVDFMKIADAAQDVVRPAMPSECLVDRSAMMMGYAGCYSSFLKHAEGHAERYGV 319 Query: 311 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAA 347 A ++L AG RKL+GGQEDQLIDIALE+K++ +A A Sbjct: 320 SAAEILIEAGNRKLVGGQEDQLIDIALELKKKADANA 356 >tr|D1AB65|D1AB65_THECD Tax_Id=471852 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Thermomonospora curvata] Length = 344 Score = 490 bits (1262), Expect = e-136 Identities = 245/335 (73%), Positives = 277/335 (82%) Query: 11 DVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 70 D+R+TD+SLRDGSH KRHQFT + V S+VAALD AGVPVIEV HGDGLGGSSF YGFSKT Sbjct: 9 DIRVTDSSLRDGSHAKRHQFTVDHVTSVVAALDEAGVPVIEVAHGDGLGGSSFTYGFSKT 68 Query: 71 PEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFG 130 PEQELIK A +TA +KIAFLMLPGVG K+DI+EA +NG ICRIATHCTEADVS+QHFG Sbjct: 69 PEQELIKAAVKTATRAKIAFLMLPGVGVKDDIREAADNGAQICRIATHCTEADVSVQHFG 128 Query: 131 LARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQAL 190 LAR+LGLETVGFLMMAH+ PE LA+QARIMADAGCQCVYVVDSAGAL+LE DR+ AL Sbjct: 129 LARDLGLETVGFLMMAHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILEETSDRIAAL 188 Query: 191 VAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 250 VAELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RR GAGAGN P+EA I V D Sbjct: 189 VAELGDDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSVRRLGAGAGNTPLEAFIAVCD 248 Query: 251 KIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYGV 310 K+G++TG+D F I CLL R ++MGY+GVYSSFLKHA R +ERYGV Sbjct: 249 KLGIRTGVDVFKIVDAAEDVVRPVMDSECLLGRMEIMMGYAGVYSSFLKHADRLAERYGV 308 Query: 311 PAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEA 345 Q+L RAG+RKL+GGQEDQLIDIA+E+ +EQ A Sbjct: 309 SGAQILVRAGERKLVGGQEDQLIDIAIELAKEQAA 343 >tr|D4SHM7|D4SHM7_9ACTO Tax_Id=585531 (mhpE)SubName: Full=4-hydroxy-2-oxovalerate aldolase; EC=4.1.3.39;[Aeromicrobium marinum DSM 15272] Length = 356 Score = 486 bits (1251), Expect = e-135 Identities = 244/330 (73%), Positives = 274/330 (83%) Query: 11 DVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 70 D+R+TDT LRDGSHHKRHQF +EVRSIV ALDAAG+PVIEVTHGDGLGGSSFNYGFS+T Sbjct: 22 DLRLTDTCLRDGSHHKRHQFVPDEVRSIVGALDAAGIPVIEVTHGDGLGGSSFNYGFSRT 81 Query: 71 PEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFG 130 PEQELIK+AAETA ++IAFLMLPGVGTK+DI+ AQ+NGG ICRIATHCTEAD S QHFG Sbjct: 82 PEQELIKLAAETATRARIAFLMLPGVGTKDDIRAAQDNGGQICRIATHCTEADTSRQHFG 141 Query: 131 LARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQAL 190 LARELGLETVGFLMM+HT SPE LA+QARIM DAGCQCVYVVDSAGALV+EGV DRV A+ Sbjct: 142 LARELGLETVGFLMMSHTQSPETLARQARIMVDAGCQCVYVVDSAGALVMEGVADRVAAV 201 Query: 191 VAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 250 VAE+G +A VGFHGHENLGLGVAN+V A RAGA QIDGS RRFGAGAGN P+EA IGV D Sbjct: 202 VAEIGGEATVGFHGHENLGLGVANTVIAARAGATQIDGSVRRFGAGAGNTPLEAFIGVAD 261 Query: 251 KIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYGV 310 K+G TG+DF I C L+R L+MGY+GVYSSFLKHA +ERY V Sbjct: 262 KLGWNTGVDFLQIVDAAEDVVRPAMPEECTLNRMTLMMGYAGVYSSFLKHAGNAAERYDV 321 Query: 311 PAHQLLHRAGQRKLIGGQEDQLIDIALEIK 340 ++L AG+R+LIGGQEDQLIDIAL +K Sbjct: 322 SGAKILLEAGRRQLIGGQEDQLIDIALMLK 351 >sp|C1AYB4|HOA5_RHOOB Tax_Id=632772 RecName: Full=4-hydroxy-2-oxovalerate aldolase 5; Short=HOA 5; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 5; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 5;[Rhodococcus opacus] Length = 352 Score = 479 bits (1232), Expect = e-133 Identities = 245/342 (71%), Positives = 276/342 (80%), Gaps = 3/342 (0%) Query: 11 DVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 70 D+R+TD+SLRDGSH KRHQFT E VRSIV ALDAAGVPVIEVTHGDGLGGSSFNYGFS T Sbjct: 8 DIRVTDSSLRDGSHAKRHQFTVEHVRSIVGALDAAGVPVIEVTHGDGLGGSSFNYGFSHT 67 Query: 71 PEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFG 130 PEQELIK A ETA+++KIAFLMLPG+G + DI+EA +NG SICRIATHCTEAD+S+QHFG Sbjct: 68 PEQELIKAAVETAEQAKIAFLMLPGLGVRSDIREAADNGASICRIATHCTEADISVQHFG 127 Query: 131 LARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQAL 190 LAR+LGLETVGFLMM+H+ PE LA+QARIMADAGCQCVYVVDSAGAL+L V DRV AL Sbjct: 128 LARDLGLETVGFLMMSHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILNAVSDRVSAL 187 Query: 191 VAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 250 VAELG DAQVGFHGHENLGLGVANSV AV AGA QIDGS RRFGAGAGN PVEA V + Sbjct: 188 VAELGDDAQVGFHGHENLGLGVANSVLAVEAGALQIDGSTRRFGAGAGNTPVEAFAAVTE 247 Query: 251 KIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYGV 310 K+G++TGID I CLLDR +L MGY+GVYSSFLKHA + RYGV Sbjct: 248 KLGIRTGIDTLKIIDAAEDVVRPIMDGDCLLDRLSLTMGYAGVYSSFLKHADSHASRYGV 307 Query: 311 PAHQLLHRAGQRKLIGGQEDQLIDIALEI---KREQEAAASK 349 ++L AG+RKL+GGQEDQLI+IAL + K + A A K Sbjct: 308 SGAEILIEAGRRKLVGGQEDQLIEIALGLADRKSAETAVAEK 349 >sp|Q0S4F8|HOA4_RHOSR Tax_Id=101510 RecName: Full=4-hydroxy-2-oxovalerate aldolase 4; Short=HOA 4; EC=4.1.3.39; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 4; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 4;[Rhodococcus sp.] Length = 352 Score = 475 bits (1222), Expect = e-132 Identities = 240/327 (73%), Positives = 269/327 (82%) Query: 11 DVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 70 D+R+TD+SLRDGSH KRHQFT E VRSIV ALDAAGVPVIEVTHGDGLGGSSFNYGFS T Sbjct: 8 DIRVTDSSLRDGSHAKRHQFTVEHVRSIVGALDAAGVPVIEVTHGDGLGGSSFNYGFSHT 67 Query: 71 PEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFG 130 PEQELIK A ETA+ ++IAFLMLPG+G + DI+EA +NG SICRIATHCTEAD+S+QHFG Sbjct: 68 PEQELIKAAVETAERARIAFLMLPGLGVQSDIREAADNGASICRIATHCTEADISVQHFG 127 Query: 131 LARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQAL 190 LARELGLETVGFLMM+H+ PE LA+QARIMADAGCQCVYVVDSAGAL+L V DRV AL Sbjct: 128 LARELGLETVGFLMMSHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILNAVSDRVSAL 187 Query: 191 VAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 250 VAELG DAQVGFHGHENLGLGVANSV AV AGA QIDGS RRFGAGAGN PVEA V + Sbjct: 188 VAELGDDAQVGFHGHENLGLGVANSVLAVEAGALQIDGSTRRFGAGAGNTPVEAFAAVTE 247 Query: 251 KIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYGV 310 K+G++TGID I C LDR +L+MGY+GVYSSFLKHA + RYGV Sbjct: 248 KLGIRTGIDTLKIIDAAEDVVRPIMDGDCQLDRLSLMMGYAGVYSSFLKHADSHARRYGV 307 Query: 311 PAHQLLHRAGQRKLIGGQEDQLIDIAL 337 ++L AG+RKL+GGQEDQLI+IAL Sbjct: 308 SGAEILIEAGRRKLVGGQEDQLIEIAL 334 >tr|D3F7A6|D3F7A6_CONWI Tax_Id=469383 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Conexibacter woesei] Length = 349 Score = 437 bits (1125), Expect = e-121 Identities = 220/338 (65%), Positives = 265/338 (78%), Gaps = 2/338 (0%) Query: 11 DVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 70 DVR+TDT LRDGSH H+FT E+VR +VAALDAAGVPV+EVTHGDGLGGSS+NYGFS T Sbjct: 12 DVRVTDTCLRDGSHAVGHRFTREQVRDVVAALDAAGVPVLEVTHGDGLGGSSYNYGFSGT 71 Query: 71 PEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFG 130 PE+ELI A TA+ ++IA LMLPGVGT +DI+ + G + R+ATHCTEADV+IQHFG Sbjct: 72 PERELIATAVATARRARIAALMLPGVGTADDIRAVADLGVEVIRVATHCTEADVAIQHFG 131 Query: 131 LARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVQAL 190 LARELGLETVGFLMM+H+ P+ LA QAR+MADAGCQCVYVVDSAGALVLE V +RV+A+ Sbjct: 132 LARELGLETVGFLMMSHSQPPDVLAAQARVMADAGCQCVYVVDSAGALVLEQVAERVEAV 191 Query: 191 VAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 250 AELG DAQVGFHGHENLGL +AN+V AVRAGA Q+DG RR GAGAGN P EAL V + Sbjct: 192 GAELGDDAQVGFHGHENLGLAIANTVAAVRAGAAQVDGCTRRLGAGAGNTPTEALAAVCE 251 Query: 251 KIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAIRQSERYGV 310 K+G++TG+D + C LDR AL++GY+GVYSSFLKHA R +ERYGV Sbjct: 252 KLGIETGLDVLALADAAEEVVRPAMAAECTLDRGALLLGYAGVYSSFLKHAERSAERYGV 311 Query: 311 PAHQLLHRAGQRKLIGGQEDQLIDIALEI--KREQEAA 346 Q+L G+R+L+GGQEDQ+I IA ++ R++EAA Sbjct: 312 STAQILLACGERRLVGGQEDQIIAIAADLAAARKEEAA 349 >tr|D5UYS5|D5UYS5_TSUPA Tax_Id=521096 SubName: Full=4-hydroxy-2-oxovalerate aldolase;[Tsukamurella paurometabola DSM 20162] Length = 349 Score = 414 bits (1063), Expect = e-113 Identities = 210/343 (61%), Positives = 256/343 (74%) Query: 3 DIFFNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSS 62 D++ +P DVR+ DTSLRDGSH HQFT + VR V ALD AGV +IEVTHGDGLGGS+ Sbjct: 7 DLWNDPDRDVRIVDTSLRDGSHAMAHQFTEQNVRDTVRALDDAGVSLIEVTHGDGLGGST 66 Query: 63 FNYGFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEA 122 FNYGFS E++LI A + A+++KIA LMLPG+GT EDI+ A + G RIATHCTEA Sbjct: 67 FNYGFSLVDERKLIAAAVDEAQQAKIAVLMLPGLGTVEDIRVAADLGAGALRIATHCTEA 126 Query: 123 DVSIQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEG 182 DVSIQHFG ARELGLETVGFLM++H +PE LA+QARIMADAGCQCVYVVDSAGAL+LE Sbjct: 127 DVSIQHFGAARELGLETVGFLMLSHMSAPEALAKQARIMADAGCQCVYVVDSAGALILED 186 Query: 183 VRDRVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPV 242 DRV ALVAELG+DA VG+HGH+NL GVANSV A RAGAKQIDGS GAGAGN+P Sbjct: 187 AADRVAALVAELGADAHVGYHGHQNLSFGVANSVLAYRAGAKQIDGSLLALGAGAGNSPT 246 Query: 243 EALIGVFDKIGVKTGIDFFDIXXXXXXXXXXXXXXXCLLDRNALIMGYSGVYSSFLKHAI 302 E L F+++GV+TG D + ++DR++++ GY+GVYSSFL HA Sbjct: 247 EVLAATFERLGVRTGTDKDALMAAAEDVVKPYITRLPVMDRSSIVQGYAGVYSSFLLHAE 306 Query: 303 RQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEA 345 R + RYGVPAH++L+ G+R +GGQED +I IA+E+ Q A Sbjct: 307 RAAARYGVPAHEILYECGRRGYVGGQEDMIIAIAVEMSAAQTA 349 Database: Amellifera_nr Posted date: Jul 23, 2010 5:10 AM Number of letters in database: 4,236,830,644 Number of sequences in database: 12,507,864 Lambda K H 0.320 0.136 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 12507864 Number of Hits to DB: 2,652,908,291 Number of extensions: 105257927 Number of successful extensions: 299490 Number of sequences better than 10.0: 4660 Number of HSP's gapped: 299216 Number of HSP's successfully gapped: 4677 Length of query: 349 Length of database: 4,236,830,644 Length adjustment: 139 Effective length of query: 210 Effective length of database: 2,498,237,548 Effective search space: 524629885080 Effective search space used: 524629885080 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 81 (35.8 bits)