BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_6075
         (163 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|A0R559|A0R559_MYCS2 Tax_Id=246196 (ispF)RecName: Full=2-C-met...   234   3e-60
tr|A3Q6W1|A3Q6W1_MYCSJ Tax_Id=164757 (ispF)RecName: Full=2-C-met...   192   1e-47
tr|Q1B2P2|Q1B2P2_MYCSS Tax_Id=164756 (ispF)RecName: Full=2-C-met...   190   6e-47
tr|A1UMF6|A1UMF6_MYCSK Tax_Id=189918 (ispF)RecName: Full=2-C-met...   190   6e-47
tr|A4T5L7|A4T5L7_MYCGI Tax_Id=350054 (ispF)RecName: Full=2-C-met...   177   3e-43
sp|A1TG10|ISPF_MYCVP Tax_Id=350058 (ispF)RecName: Full=2-C-methy...   176   6e-43
sp|Q743W4|ISPF_MYCPA Tax_Id=1770 (ispF)RecName: Full=2-C-methyl-...   172   2e-41
sp|A0QAB4|ISPF_MYCA1 Tax_Id=243243 (ispF)RecName: Full=2-C-methy...   172   2e-41
sp|B1MGY4|ISPF_MYCA9 Tax_Id=561007 (ispF)RecName: Full=2-C-methy...   165   1e-39
tr|D5PZ29|D5PZ29_COREQ Tax_Id=525370 (ispF)SubName: Full=2-C-met...   164   4e-39
tr|D5P8L0|D5P8L0_9MYCO Tax_Id=525368 (ispF)SubName: Full=2-C-met...   162   1e-38
tr|C3JUN0|C3JUN0_RHOER Tax_Id=596309 (ispF)RecName: Full=2-C-met...   160   4e-38
sp|C0ZPR8|ISPF_RHOE4 Tax_Id=234621 (ispF)RecName: Full=2-C-methy...   158   2e-37
sp|P65183|ISPF_MYCTU Tax_Id=1773 (ispF)RecName: Full=2-C-methyl-...   157   4e-37
sp|A5U8Q6|ISPF_MYCTA Tax_Id=419947 (ispF)RecName: Full=2-C-methy...   157   4e-37
sp|C1AI40|ISPF_MYCBT Tax_Id=561275 (ispF)RecName: Full=2-C-methy...   157   4e-37
sp|A1KPR7|ISPF_MYCBP Tax_Id=410289 (ispF)RecName: Full=2-C-methy...   157   4e-37
sp|P65184|ISPF_MYCBO Tax_Id=1765 (ispF)RecName: Full=2-C-methyl-...   157   4e-37
tr|C6DMN3|C6DMN3_MYCTK Tax_Id=478434 (ispF)RecName: Full=2-C-met...   157   4e-37
tr|A5WTF0|A5WTF0_MYCTF Tax_Id=336982 (ispF)RecName: Full=2-C-met...   157   4e-37
tr|D6G4S1|D6G4S1_MYCTU Tax_Id=478435 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|D6FT64|D6FT64_MYCTU Tax_Id=611304 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|D6FHJ1|D6FHJ1_MYCTU Tax_Id=611303 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|D6EYS9|D6EYS9_MYCTU Tax_Id=611302 SubName: Full=2C-methyl-D-e...   157   4e-37
tr|D5ZMC5|D5ZMC5_MYCTU Tax_Id=537210 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|D5ZAF5|D5ZAF5_MYCTU Tax_Id=537209 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|D5YXK2|D5YXK2_MYCTU Tax_Id=515616 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|D5YL31|D5YL31_MYCTU Tax_Id=520140 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|D5Y9I1|D5Y9I1_MYCTU Tax_Id=520141 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|D5XZS2|D5XZS2_MYCTU Tax_Id=515617 SubName: Full=2-C-methyl-D-...   157   4e-37
tr|A4KM66|A4KM66_MYCTU Tax_Id=395095 (ispF)RecName: Full=2-C-met...   157   4e-37
tr|A2VPY9|A2VPY9_MYCTU Tax_Id=348776 (ispF)RecName: Full=2-C-met...   157   4e-37
tr|D5USV4|D5USV4_TSUPA Tax_Id=521096 SubName: Full=2C-methyl-D-e...   156   9e-37
sp|Q0S889|ISPF_RHOSR Tax_Id=101510 (ispF)RecName: Full=2-C-methy...   154   4e-36
sp|C1BAC3|ISPF_RHOOB Tax_Id=632772 (ispF)RecName: Full=2-C-methy...   154   4e-36
sp|B2HJ22|ISPF_MYCMM Tax_Id=216594 (ispF)RecName: Full=2-C-methy...   152   2e-35
sp|Q5Z2R2|ISPF_NOCFA Tax_Id=37329 (ispF)RecName: Full=2-C-methyl...   146   7e-34
tr|D2S7D1|D2S7D1_GEOOG Tax_Id=526225 (ispF)RecName: Full=2-C-met...   146   9e-34
tr|C6WGL5|C6WGL5_ACTMD Tax_Id=446462 (ispF)RecName: Full=2-C-met...   146   9e-34
tr|C7MQ49|C7MQ49_SACVD Tax_Id=471857 (ispF)RecName: Full=2-C-met...   145   2e-33
tr|A4F6W4|A4F6W4_SACEN Tax_Id=405948 (ispF)RecName: Full=2-C-met...   145   2e-33
tr|A0PV28|A0PV28_MYCUA Tax_Id=362242 (ispF)SubName: Full=2C-meth...   144   3e-33
tr|D0L459|D0L459_GORB4 Tax_Id=526226 (ispF)RecName: Full=2-C-met...   143   6e-33
tr|D3CD49|D3CD49_9ACTO Tax_Id=648999 (ispF)RecName: Full=2-C-met...   142   2e-32
tr|D1S8E7|D1S8E7_9ACTO Tax_Id=644283 (ispF)RecName: Full=2-C-met...   142   2e-32

>tr|A0R559|A0R559_MYCS2 Tax_Id=246196 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium smegmatis]
          Length = 163

 Score =  234 bits (596), Expect = 3e-60
 Identities = 121/163 (74%), Positives = 121/163 (74%)

Query: 1   MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXX 60
           MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAH               
Sbjct: 1   MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHALCDALLSAAGLGDL 60

Query: 61  XTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS 120
            TIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS
Sbjct: 61  GTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS 120

Query: 121 ELVGAPVSVSXXXXXXXXXXXXXXXXXXXXXXXXXXEPVGDAK 163
           ELVGAPVSVS                          EPVGDAK
Sbjct: 121 ELVGAPVSVSATTTDGLGLTGRGEGLAAIATALVAAEPVGDAK 163


>tr|A3Q6W1|A3Q6W1_MYCSJ Tax_Id=164757 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  192 bits (487), Expect = 1e-47
 Identities = 92/130 (70%), Positives = 102/130 (78%)

Query: 1   MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXX 60
           M LPRVGLGTDVHPIE GRPCRLL L FD ADGCAGHSDGDVAAH               
Sbjct: 1   MSLPRVGLGTDVHPIEPGRPCRLLGLHFDGADGCAGHSDGDVAAHALCDALLSAAGLGDL 60

Query: 61  XTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS 120
             +FGT RP+W G SGADM+RHVRGL++ AGF +GNATVQVIGNRPK+GPRR EAQ++LS
Sbjct: 61  GGVFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLS 120

Query: 121 ELVGAPVSVS 130
           EL+GAPVSVS
Sbjct: 121 ELIGAPVSVS 130


>tr|Q1B2P2|Q1B2P2_MYCSS Tax_Id=164756 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  190 bits (482), Expect = 6e-47
 Identities = 91/130 (70%), Positives = 101/130 (77%)

Query: 1   MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXX 60
           M LPRVGLGTDVHPIE GRPCRLL L FD  DGCAGHSDGDVAAH               
Sbjct: 1   MSLPRVGLGTDVHPIEPGRPCRLLGLHFDGEDGCAGHSDGDVAAHALCDALLSAAGLGDL 60

Query: 61  XTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS 120
             +FGT RP+W G SGADM+RHVRGL++ AGF +GNATVQVIGNRPK+GPRR EAQ++LS
Sbjct: 61  GGVFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLS 120

Query: 121 ELVGAPVSVS 130
           EL+GAPVSVS
Sbjct: 121 ELIGAPVSVS 130


>tr|A1UMF6|A1UMF6_MYCSK Tax_Id=189918 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium sp.]
          Length = 158

 Score =  190 bits (482), Expect = 6e-47
 Identities = 91/130 (70%), Positives = 101/130 (77%)

Query: 1   MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXX 60
           M LPRVGLGTDVHPIE GRPCRLL L FD  DGCAGHSDGDVAAH               
Sbjct: 1   MSLPRVGLGTDVHPIEPGRPCRLLGLHFDGEDGCAGHSDGDVAAHALCDALLSAAGLGDL 60

Query: 61  XTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS 120
             +FGT RP+W G SGADM+RHVRGL++ AGF +GNATVQVIGNRPK+GPRR EAQ++LS
Sbjct: 61  GGVFGTGRPEWEGVSGADMLRHVRGLLQEAGFRVGNATVQVIGNRPKIGPRRAEAQELLS 120

Query: 121 ELVGAPVSVS 130
           EL+GAPVSVS
Sbjct: 121 ELIGAPVSVS 130


>tr|A4T5L7|A4T5L7_MYCGI Tax_Id=350054 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium gilvum]
          Length = 160

 Score =  177 bits (450), Expect = 3e-43
 Identities = 86/126 (68%), Positives = 94/126 (74%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVGLGTDVHPIEAGRPCRLLCL FDD DGCAGHSDGDVAAH                 +F
Sbjct: 5   RVGLGTDVHPIEAGRPCRLLCLLFDDGDGCAGHSDGDVAAHALCDALLSAAGMGDIGEVF 64

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT  PQWR  SGADM+RHV  L+   GF +GNA VQVIGNRPK+GPRR EAQ++LSEL+ 
Sbjct: 65  GTGLPQWRDVSGADMLRHVHTLLVEQGFQVGNAAVQVIGNRPKIGPRRAEAQRILSELLD 124

Query: 125 APVSVS 130
           APVSVS
Sbjct: 125 APVSVS 130


>sp|A1TG10|ISPF_MYCVP Tax_Id=350058 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium vanbaalenii]
          Length = 162

 Score =  176 bits (447), Expect = 6e-43
 Identities = 88/131 (67%), Positives = 97/131 (74%), Gaps = 2/131 (1%)

Query: 2   MLP--RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXX 59
           MLP  RVGLGTDVHPIEAGRPC LLCL FDDADGCAGHSDGDVAAH              
Sbjct: 1   MLPSIRVGLGTDVHPIEAGRPCWLLCLLFDDADGCAGHSDGDVAAHALCDALLSAAGMGD 60

Query: 60  XXTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVL 119
              +FGT  PQWRG SGADM+RHV  ++   G  +GNA VQVIGNRPK+GPRR EAQ+VL
Sbjct: 61  IGEVFGTGLPQWRGVSGADMLRHVHSMMTAEGLRVGNAAVQVIGNRPKIGPRRAEAQRVL 120

Query: 120 SELVGAPVSVS 130
           S ++GAPVSVS
Sbjct: 121 SGILGAPVSVS 131


>sp|Q743W4|ISPF_MYCPA Tax_Id=1770 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium paratuberculosis]
          Length = 159

 Score =  172 bits (435), Expect = 2e-41
 Identities = 83/127 (65%), Positives = 92/127 (72%)

Query: 4   PRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTI 63
           PR+GLG DVHPI+ GRPCRLL L FDDADGCAGHSDGDV AH                 +
Sbjct: 5   PRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGDVGAV 64

Query: 64  FGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELV 123
           FG D P+W G SGADM+RHV  L    GF +GNA VQVIGNRPKVGPRR EAQ+VLSEL+
Sbjct: 65  FGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVLSELL 124

Query: 124 GAPVSVS 130
           GAPVSV+
Sbjct: 125 GAPVSVA 131


>sp|A0QAB4|ISPF_MYCA1 Tax_Id=243243 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium avium]
          Length = 159

 Score =  172 bits (435), Expect = 2e-41
 Identities = 83/127 (65%), Positives = 92/127 (72%)

Query: 4   PRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTI 63
           PR+GLG DVHPI+ GRPCRLL L FDDADGCAGHSDGDV AH                 +
Sbjct: 5   PRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGDVGAV 64

Query: 64  FGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELV 123
           FG D P+W G SGADM+RHV  L    GF +GNA VQVIGNRPKVGPRR EAQ+VLSEL+
Sbjct: 65  FGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVLSELL 124

Query: 124 GAPVSVS 130
           GAPVSV+
Sbjct: 125 GAPVSVA 131


>sp|B1MGY4|ISPF_MYCA9 Tax_Id=561007 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium abscessus]
          Length = 158

 Score =  165 bits (418), Expect = 1e-39
 Identities = 81/128 (63%), Positives = 92/128 (71%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVG+GTDVHPIE G+PC LL L F D +GC GHSDGDVAAH                 
Sbjct: 4   LPRVGIGTDVHPIEEGKPCWLLGLLFSDENGCEGHSDGDVAAHALCDALLSAAGLGDVGA 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FGT RP+W G SGA M+ HVR L+ + GF IGNA VQVIGNRPKVGPRR EAQ++LS L
Sbjct: 64  VFGTGRPEWTGVSGAKMLSHVRDLLHDNGFQIGNAAVQVIGNRPKVGPRRAEAQELLSGL 123

Query: 123 VGAPVSVS 130
           +GAPVSVS
Sbjct: 124 IGAPVSVS 131


>tr|D5PZ29|D5PZ29_COREQ Tax_Id=525370 (ispF)SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Rhodococcus equi ATCC 33707]
          Length = 158

 Score =  164 bits (414), Expect = 4e-39
 Identities = 77/126 (61%), Positives = 94/126 (74%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVG+GTDVHP+E GRPC +  L FDDADGCAGHSDGDVAAH                ++F
Sbjct: 2   RVGIGTDVHPVEKGRPCWMAGLLFDDADGCAGHSDGDVAAHALCDALLSAAGLGDLGSVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT RP+W G SG  M+  VR L+ +AG+ +GNA+VQVIGNRPK+GPRREEAQ+VL +++G
Sbjct: 62  GTGRPEWDGVSGVRMLTEVRRLLGDAGYTVGNASVQVIGNRPKIGPRREEAQRVLGDVLG 121

Query: 125 APVSVS 130
           APVSVS
Sbjct: 122 APVSVS 127


>tr|D5P8L0|D5P8L0_9MYCO Tax_Id=525368 (ispF)SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Mycobacterium parascrofulaceum
           ATCC BAA-614]
          Length = 159

 Score =  162 bits (410), Expect = 1e-38
 Identities = 79/128 (61%), Positives = 91/128 (71%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLG DVHPIE GRPC L+ L F  ADGCAGHSDGDV AH                 
Sbjct: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPGADGCAGHSDGDVGAHALCDALLSAAGLGDIGA 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  LV   G  +GNA VQ+IGN+P++GPRR EAQ+VLSEL
Sbjct: 64  VFGVDDPRWKGVSGADMLRHVGDLVARDGLRVGNAVVQLIGNQPRIGPRRAEAQRVLSEL 123

Query: 123 VGAPVSVS 130
           +GAPVSVS
Sbjct: 124 LGAPVSVS 131


>tr|C3JUN0|C3JUN0_RHOER Tax_Id=596309 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Rhodococcus erythropolis SK121]
          Length = 158

 Score =  160 bits (406), Expect = 4e-38
 Identities = 77/126 (61%), Positives = 92/126 (73%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVGLGTDVHPIE GRPC +  L F++ADGC+GHSDGDVA H                ++F
Sbjct: 2   RVGLGTDVHPIEVGRPCWMAGLLFEEADGCSGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT RP+W G SGA M+  VR L+E   F +GNA VQVIGNRPK+GPRR+EAQ+VLSE++G
Sbjct: 62  GTGRPEWDGVSGARMLAEVRRLLEENQFAVGNAAVQVIGNRPKIGPRRDEAQKVLSEILG 121

Query: 125 APVSVS 130
           APVSVS
Sbjct: 122 APVSVS 127


>sp|C0ZPR8|ISPF_RHOE4 Tax_Id=234621 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus erythropolis]
          Length = 158

 Score =  158 bits (399), Expect = 2e-37
 Identities = 76/126 (60%), Positives = 91/126 (72%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVGLGTDVHPIE GRPC +  L F++ADGC+GHSDGDVA H                ++F
Sbjct: 2   RVGLGTDVHPIEVGRPCWMAGLLFEEADGCSGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT RP+W G SGA M+  VR L+E   F +GNA VQVIGNRPK+GPRR EAQ+VLS+++G
Sbjct: 62  GTGRPEWDGVSGARMLAEVRRLLEENQFTVGNAAVQVIGNRPKIGPRRGEAQKVLSDILG 121

Query: 125 APVSVS 130
           APVSVS
Sbjct: 122 APVSVS 127


>sp|P65183|ISPF_MYCTU Tax_Id=1773 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>sp|A5U8Q6|ISPF_MYCTA Tax_Id=419947 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>sp|C1AI40|ISPF_MYCBT Tax_Id=561275 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>sp|A1KPR7|ISPF_MYCBP Tax_Id=410289 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>sp|P65184|ISPF_MYCBO Tax_Id=1765 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium bovis]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|C6DMN3|C6DMN3_MYCTK Tax_Id=478434 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|A5WTF0|A5WTF0_MYCTF Tax_Id=336982 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium tuberculosis]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D6G4S1|D6G4S1_MYCTU Tax_Id=478435 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase ispF;[Mycobacterium tuberculosis KZN 605]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D6FT64|D6FT64_MYCTU Tax_Id=611304 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase ispF;[Mycobacterium tuberculosis K85]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D6FHJ1|D6FHJ1_MYCTU Tax_Id=611303 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase ispF;[Mycobacterium tuberculosis CPHL_A]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D6EYS9|D6EYS9_MYCTU Tax_Id=611302 SubName:
           Full=2C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase;[Mycobacterium tuberculosis T46]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITRHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D5ZMC5|D5ZMC5_MYCTU Tax_Id=537210 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase ispF;[Mycobacterium tuberculosis T17]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITRHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D5ZAF5|D5ZAF5_MYCTU Tax_Id=537209 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase ispF;[Mycobacterium tuberculosis GM 1503]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D5YXK2|D5YXK2_MYCTU Tax_Id=515616 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase ispF;[Mycobacterium tuberculosis 02_1987]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D5YL31|D5YL31_MYCTU Tax_Id=520140 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase;[Mycobacterium tuberculosis EAS054]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITRHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D5Y9I1|D5Y9I1_MYCTU Tax_Id=520141 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase ispF;[Mycobacterium tuberculosis T85]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D5XZS2|D5XZS2_MYCTU Tax_Id=515617 SubName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase ispF;[Mycobacterium tuberculosis T92]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITRHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|A4KM66|A4KM66_MYCTU Tax_Id=395095 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium tuberculosis str. Haarlem]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|A2VPY9|A2VPY9_MYCTU Tax_Id=348776 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Mycobacterium tuberculosis C]
          Length = 159

 Score =  157 bits (397), Expect = 4e-37
 Identities = 79/128 (61%), Positives = 89/128 (69%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLGTDVHPIE GRPC L+ L F  ADGCAGHSDGDVA H                 
Sbjct: 4   LPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGE 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG D P+W+G SGADM+RHV  L+   G+ +GNA VQVIGNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>tr|D5USV4|D5USV4_TSUPA Tax_Id=521096 SubName:
           Full=2C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; EC=4.6.1.12;[Tsukamurella paurometabola DSM
           20162]
          Length = 157

 Score =  156 bits (394), Expect = 9e-37
 Identities = 78/130 (60%), Positives = 93/130 (71%), Gaps = 1/130 (0%)

Query: 1   MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXX 60
           M++PRVG+GTDVHP+E GR C +L L FD  DGC+GHSDGDVA H               
Sbjct: 1   MIIPRVGIGTDVHPVEPGRECWMLGLLFD-GDGCSGHSDGDVAVHALCDALLSAGGLGDL 59

Query: 61  XTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS 120
            T+FG  R    G +GA+M+ HVR L+  AGF +GNA VQ+IGNRPKVGPRR+EAQQVLS
Sbjct: 60  GTVFGVGRSDNVGITGAEMLTHVRTLLSEAGFAVGNAAVQLIGNRPKVGPRRDEAQQVLS 119

Query: 121 ELVGAPVSVS 130
           EL+GAPVSVS
Sbjct: 120 ELLGAPVSVS 129


>sp|Q0S889|ISPF_RHOSR Tax_Id=101510 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus sp.]
          Length = 158

 Score =  154 bits (388), Expect = 4e-36
 Identities = 74/126 (58%), Positives = 89/126 (70%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVG+GTDVHPIE GRPC +  L F+D +GCAGHSDGDVA H                ++F
Sbjct: 2   RVGIGTDVHPIEQGRPCWMAGLLFEDENGCAGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT RP+W G SGA M+  VR L+E   F + NA VQVIGNRPK+GPRR EAQ+VLS+++G
Sbjct: 62  GTGRPEWSGVSGAAMLAEVRRLLEEDDFDVANAAVQVIGNRPKIGPRRNEAQKVLSDILG 121

Query: 125 APVSVS 130
           APVSVS
Sbjct: 122 APVSVS 127


>sp|C1BAC3|ISPF_RHOOB Tax_Id=632772 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Rhodococcus opacus]
          Length = 158

 Score =  154 bits (388), Expect = 4e-36
 Identities = 74/126 (58%), Positives = 89/126 (70%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVG+GTDVHPIE GRPC +  L F+D +GCAGHSDGDVA H                ++F
Sbjct: 2   RVGIGTDVHPIEQGRPCWMAGLLFEDENGCAGHSDGDVAVHALCDALLSAAGLGDLGSVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT RP+W G SGA M+  VR L+E   F + NA VQVIGNRPK+GPRR EAQ+VLS+++G
Sbjct: 62  GTGRPEWSGVSGAAMLAEVRRLLEQDDFGVANAAVQVIGNRPKIGPRRNEAQKVLSDILG 121

Query: 125 APVSVS 130
           APVSVS
Sbjct: 122 APVSVS 127


>sp|B2HJ22|ISPF_MYCMM Tax_Id=216594 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Mycobacterium marinum]
          Length = 165

 Score =  152 bits (383), Expect = 2e-35
 Identities = 76/128 (59%), Positives = 87/128 (67%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVGLG DVHPIE GRPC L+ L F  ADGCAGHSDGDVAAH                 
Sbjct: 4   LPRVGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGD 63

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           +FG   P+W G SGA M+RHV  L+   G+ +GNA+VQV+GNRPK+G RR EAQ VLS L
Sbjct: 64  VFGVGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRL 123

Query: 123 VGAPVSVS 130
           + APVSVS
Sbjct: 124 LNAPVSVS 131


>sp|Q5Z2R2|ISPF_NOCFA Tax_Id=37329 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECPS; Short=MECDP-synthase;
           EC=4.6.1.12;[Nocardia farcinica]
          Length = 155

 Score =  146 bits (369), Expect = 7e-34
 Identities = 72/126 (57%), Positives = 86/126 (68%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVG+G+DVHPIE GRPC +  L F+  DGC+GHSDGDVAAH                 +F
Sbjct: 2   RVGIGSDVHPIEPGRPCWMAGLLFEGEDGCSGHSDGDVAAHALCDALLSAAGLGDVGAVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT RP+W   SGA M+  VR L+  AGF + NA VQVIGNRPK+GPRR EAQ+VL +L+ 
Sbjct: 62  GTGRPEWADVSGAAMLTEVRRLLGEAGFEVVNAAVQVIGNRPKIGPRRAEAQRVLGDLLD 121

Query: 125 APVSVS 130
           APVSVS
Sbjct: 122 APVSVS 127


>tr|D2S7D1|D2S7D1_GEOOG Tax_Id=526225 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Geodermatophilus obscurus]
          Length = 167

 Score =  146 bits (368), Expect = 9e-34
 Identities = 70/128 (54%), Positives = 87/128 (67%)

Query: 3   LPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXT 62
           LPRVG+G DVHP+ AGR C L  L++   DGCAGHSDGDV AH                 
Sbjct: 5   LPRVGVGVDVHPVAAGRTCWLAGLQWPGVDGCAGHSDGDVVAHALTDAVLSAAGLGDIGG 64

Query: 63  IFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSEL 122
           + GTD P+W GA GA ++ HVR ++E AG+ +GNA VQ++GN PKVGPRR EA+QVLS  
Sbjct: 65  LLGTDDPRWAGARGAAVLAHVREVLETAGWQVGNAAVQLVGNTPKVGPRRAEAEQVLSRA 124

Query: 123 VGAPVSVS 130
           +GAPVSV+
Sbjct: 125 LGAPVSVT 132


>tr|C6WGL5|C6WGL5_ACTMD Tax_Id=446462 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Actinosynnema mirum]
          Length = 155

 Score =  146 bits (368), Expect = 9e-34
 Identities = 71/126 (56%), Positives = 86/126 (68%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVG+GTDVHP+E GR C ++ L ++ ADGCAGHSDGDVAAH                 +F
Sbjct: 2   RVGIGTDVHPVEPGRDCWMVGLLWEGADGCAGHSDGDVAAHALCDALLSAAGLGDLGAVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT  P+W GA G + +   R LVE  GFV+GNA VQVIGN P+VG RR EAQ+VLSE++G
Sbjct: 62  GTSDPRWSGAHGVEFLAEARRLVEAEGFVVGNAAVQVIGNAPRVGKRRAEAQKVLSEVLG 121

Query: 125 APVSVS 130
            PVSVS
Sbjct: 122 GPVSVS 127


>tr|C7MQ49|C7MQ49_SACVD Tax_Id=471857 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Saccharomonospora viridis]
          Length = 157

 Score =  145 bits (366), Expect = 2e-33
 Identities = 72/126 (57%), Positives = 85/126 (67%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           R+G G DVHPIE GR C L  L + DADGC+GHSDGDVA+H                 +F
Sbjct: 2   RIGQGVDVHPIEPGRECWLAGLHWPDADGCSGHSDGDVASHALCDALLSAAGLGDLGAVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT + QW GA G +++  VR  V  AG+ +GNA VQVIGNRPK+G RREEAQ+VLSE VG
Sbjct: 62  GTGQNQWAGAHGVELLAEVRTRVTEAGYRVGNAVVQVIGNRPKIGRRREEAQRVLSEAVG 121

Query: 125 APVSVS 130
           APVSVS
Sbjct: 122 APVSVS 127


>tr|A4F6W4|A4F6W4_SACEN Tax_Id=405948 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Saccharopolyspora erythraea]
          Length = 158

 Score =  145 bits (366), Expect = 2e-33
 Identities = 71/129 (55%), Positives = 87/129 (67%)

Query: 2   MLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXX 61
           M+PR+G G DVHP+EAGR C +  L +   DGCAGHSDGDVA+H                
Sbjct: 1   MIPRIGQGVDVHPVEAGRECWVAGLLWPGEDGCAGHSDGDVASHALCDALLSAAGLGDLG 60

Query: 62  TIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSE 121
            +FGT   +W GA GA+++   R  V  AGF IGNA VQV+GNRP++G RREEAQ+VLSE
Sbjct: 61  AVFGTGDDRWAGAHGAELLTEARRRVTEAGFGIGNAVVQVVGNRPRIGKRREEAQRVLSE 120

Query: 122 LVGAPVSVS 130
           +VGAPVSVS
Sbjct: 121 VVGAPVSVS 129


>tr|A0PV28|A0PV28_MYCUA Tax_Id=362242 (ispF)SubName:
           Full=2C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase IspF;[Mycobacterium ulcerans]
          Length = 159

 Score =  144 bits (364), Expect = 3e-33
 Identities = 72/125 (57%), Positives = 84/125 (67%)

Query: 6   VGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIFG 65
           +GLG DVHPIE GRPC L+ L F  ADGCAGHSDGDVAAH                 +FG
Sbjct: 1   MGLGVDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAAHALCDAVLSAAGLGDIGDVFG 60

Query: 66  TDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVGA 125
              P+W G SGA M+RHV  L+   G+ +GNA+VQV+GNRPK+G RR EAQ VLS L+ A
Sbjct: 61  VGDPRWEGVSGATMLRHVVELITQHGYRVGNASVQVVGNRPKIGWRRYEAQAVLSRLLNA 120

Query: 126 PVSVS 130
           PVSVS
Sbjct: 121 PVSVS 125


>tr|D0L459|D0L459_GORB4 Tax_Id=526226 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Gordonia bronchialis]
          Length = 152

 Score =  143 bits (361), Expect = 6e-33
 Identities = 69/126 (54%), Positives = 83/126 (65%)

Query: 5   RVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXXXTIF 64
           RVG+GTD H ++    C ++ L F D  GCAGHSDGDV AH                ++F
Sbjct: 2   RVGIGTDAHRVDENCDCWMVGLHFPDTPGCAGHSDGDVGAHALCDAVLSAAGLGDVGSVF 61

Query: 65  GTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLSELVG 124
           GT RP+W G SG  M+ HV  LV +AGF + N  VQVIGNRPK+GPRR+EAQQVLSE +G
Sbjct: 62  GTGRPEWAGVSGVAMLAHVATLVADAGFTVVNGAVQVIGNRPKIGPRRDEAQQVLSEALG 121

Query: 125 APVSVS 130
           APVSVS
Sbjct: 122 APVSVS 127


>tr|D3CD49|D3CD49_9ACTO Tax_Id=648999 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Micromonospora sp. L5]
          Length = 160

 Score =  142 bits (357), Expect = 2e-32
 Identities = 71/130 (54%), Positives = 85/130 (65%)

Query: 1   MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXX 60
           M++PRV +GTDVH   AGRPC +  L + D DG AGHSD DVAAH               
Sbjct: 1   MIVPRVAVGTDVHAFAAGRPCWVAGLHWPDQDGLAGHSDADVAAHAACNALLSAAGLGDL 60

Query: 61  XTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS 120
              FG D+P+W GASG  ++      V  AGF IGN +VQV+GNRPK+GPRREEAQ+VLS
Sbjct: 61  GANFGVDQPEWAGASGVALLTESARRVRAAGFQIGNVSVQVVGNRPKIGPRREEAQRVLS 120

Query: 121 ELVGAPVSVS 130
           E VGAPV+VS
Sbjct: 121 EAVGAPVTVS 130


>tr|D1S8E7|D1S8E7_9ACTO Tax_Id=644283 (ispF)RecName:
           Full=2-C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase; Short=MECDP-synthase; Short=MECPS;
           EC=4.6.1.12;[Micromonospora aurantiaca ATCC 27029]
          Length = 160

 Score =  142 bits (357), Expect = 2e-32
 Identities = 71/130 (54%), Positives = 85/130 (65%)

Query: 1   MMLPRVGLGTDVHPIEAGRPCRLLCLEFDDADGCAGHSDGDVAAHXXXXXXXXXXXXXXX 60
           M++PRV +GTDVH   AGRPC +  L + D DG AGHSD DVAAH               
Sbjct: 1   MIVPRVAVGTDVHAFAAGRPCWVAGLHWPDQDGLAGHSDADVAAHAACNALLSAAGLGDL 60

Query: 61  XTIFGTDRPQWRGASGADMIRHVRGLVENAGFVIGNATVQVIGNRPKVGPRREEAQQVLS 120
              FG D+P+W GASG  ++      V  AGF IGN +VQV+GNRPK+GPRREEAQ+VLS
Sbjct: 61  GANFGVDQPEWAGASGVALLTESARRVRAAGFQIGNVSVQVVGNRPKIGPRREEAQRVLS 120

Query: 121 ELVGAPVSVS 130
           E VGAPV+VS
Sbjct: 121 EAVGAPVTVS 130


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.319    0.139    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 1,055,939,896
Number of extensions: 35402023
Number of successful extensions: 58097
Number of sequences better than 10.0: 1692
Number of HSP's gapped: 56664
Number of HSP's successfully gapped: 1692
Length of query: 163
Length of database: 4,236,830,644
Length adjustment: 124
Effective length of query: 39
Effective length of database: 2,685,855,508
Effective search space: 104748364812
Effective search space used: 104748364812
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 75 (33.5 bits)