BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_6076
         (222 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|A0R560|A0R560_MYCS2 Tax_Id=246196 (ispD)RecName: Full=2-C-met...   422   e-116
tr|A3Q6W2|A3Q6W2_MYCSJ Tax_Id=164757 (ispD)RecName: Full=2-C-met...   336   1e-90
tr|Q1B2P1|Q1B2P1_MYCSS Tax_Id=164756 (ispD)RecName: Full=2-C-met...   332   3e-89
tr|A1UMF7|A1UMF7_MYCSK Tax_Id=189918 (ispD)RecName: Full=2-C-met...   332   3e-89
tr|D5P8L1|D5P8L1_9MYCO Tax_Id=525368 (ispD)SubName: Full=2-C-met...   272   2e-71
sp|Q743W5|ISPD_MYCPA Tax_Id=1770 (ispD)RecName: Full=2-C-methyl-...   257   8e-67
tr|A0QAB3|A0QAB3_MYCA1 Tax_Id=243243 (ispD)RecName: Full=2-C-met...   257   8e-67
sp|A0PV29|ISPD_MYCUA Tax_Id=362242 (ispD)RecName: Full=2-C-methy...   256   1e-66
sp|B2HJ23|ISPD_MYCMM Tax_Id=216594 (ispD)RecName: Full=2-C-methy...   256   1e-66
tr|D5YL32|D5YL32_MYCTU Tax_Id=520140 SubName: Full=2-C-methyl-D-...   255   3e-66
sp|P96864|ISPD_MYCTU Tax_Id=1773 (ispD)RecName: Full=2-C-methyl-...   254   4e-66
sp|A5U8Q7|ISPD_MYCTA Tax_Id=419947 (ispD)RecName: Full=2-C-methy...   254   4e-66
sp|C1AI41|ISPD_MYCBT Tax_Id=561275 (ispD)RecName: Full=2-C-methy...   254   4e-66
sp|A1KPR8|ISPD_MYCBP Tax_Id=410289 (ispD)RecName: Full=2-C-methy...   254   4e-66
sp|Q7TW54|ISPD_MYCBO Tax_Id=1765 (ispD)RecName: Full=2-C-methyl-...   254   4e-66
tr|C6DMN4|C6DMN4_MYCTK Tax_Id=478434 (ispD)RecName: Full=2-C-met...   254   4e-66
tr|A5WTF1|A5WTF1_MYCTF Tax_Id=336982 (ispD)RecName: Full=2-C-met...   254   4e-66
tr|D6G4S2|D6G4S2_MYCTU Tax_Id=478435 SubName: Full=4-diphosphocy...   254   4e-66
tr|D6FT65|D6FT65_MYCTU Tax_Id=611304 SubName: Full=4-diphosphocy...   254   4e-66
tr|D6FHJ2|D6FHJ2_MYCTU Tax_Id=611303 SubName: Full=4-diphosphocy...   254   4e-66
tr|D6EYT0|D6EYT0_MYCTU Tax_Id=611302 SubName: Full=2-C-methyl-D-...   254   4e-66
tr|D5ZMC6|D5ZMC6_MYCTU Tax_Id=537210 SubName: Full=4-diphosphocy...   254   4e-66
tr|D5ZAF6|D5ZAF6_MYCTU Tax_Id=537209 SubName: Full=4-diphosphocy...   254   4e-66
tr|D5YXK3|D5YXK3_MYCTU Tax_Id=515616 SubName: Full=2-C-methyl-D-...   254   4e-66
tr|D5Y9I2|D5Y9I2_MYCTU Tax_Id=520141 SubName: Full=2-C-methyl-D-...   254   4e-66
tr|D5XZS3|D5XZS3_MYCTU Tax_Id=515617 SubName: Full=4-diphosphocy...   254   4e-66
tr|A4KM67|A4KM67_MYCTU Tax_Id=395095 (ispD)RecName: Full=2-C-met...   254   4e-66
tr|A2VPZ0|A2VPZ0_MYCTU Tax_Id=348776 (ispD)RecName: Full=2-C-met...   254   4e-66
sp|C0ZPR7|ISPD_RHOE4 Tax_Id=234621 (ispD)RecName: Full=2-C-methy...   244   7e-63
tr|C3JUM9|C3JUM9_RHOER Tax_Id=596309 (ispD)RecName: Full=2-C-met...   242   2e-62
sp|Q0S890|ISPD_RHOSR Tax_Id=101510 (ispD)RecName: Full=2-C-methy...   240   1e-61
sp|C1BAC2|ISPD_RHOOB Tax_Id=632772 (ispD)RecName: Full=2-C-methy...   239   2e-61
sp|Q5Z2R3|ISPD_NOCFA Tax_Id=37329 (ispD)RecName: Full=2-C-methyl...   233   1e-59
sp|Q9CCW6|ISPD_MYCLE Tax_Id=1769 (ispD)RecName: Full=2-C-methyl-...   230   8e-59
sp|B8ZUA7|ISPD_MYCLB Tax_Id=561304 (ispD)RecName: Full=2-C-methy...   230   8e-59
tr|D5USV3|D5USV3_TSUPA Tax_Id=521096 SubName: Full=2-C-methyl-D-...   223   2e-56
tr|B1MGY3|B1MGY3_MYCA9 Tax_Id=561007 SubName: Full=Putative 2-C-...   216   2e-54
sp|Q2J542|ISPD_FRASC Tax_Id=106370 (ispD)RecName: Full=2-C-methy...   212   2e-53
tr|D1V792|D1V792_9ACTO Tax_Id=298654 (ispD)RecName: Full=2-C-met...   208   4e-52
tr|D5PZ30|D5PZ30_COREQ Tax_Id=525370 (ispD)SubName: Full=2-C-met...   201   4e-50
tr|D3DC67|D3DC67_9ACTO Tax_Id=102897 (ispD)RecName: Full=2-C-met...   198   4e-49
tr|C6WGL6|C6WGL6_ACTMD Tax_Id=446462 (ispD)RecName: Full=2-C-met...   196   1e-48
tr|C7QIR9|C7QIR9_CATAD Tax_Id=479433 SubName: Full=2-C-methyl-D-...   195   3e-48
tr|C7NK62|C7NK62_KYTSD Tax_Id=478801 SubName: Full=2C-methyl-D-e...   192   2e-47
tr|A8LF84|A8LF84_FRASN Tax_Id=298653 (ispD)RecName: Full=2-C-met...   192   2e-47

>tr|A0R560|A0R560_MYCS2 Tax_Id=246196 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium
           smegmatis]
          Length = 222

 Score =  422 bits (1084), Expect = e-116
 Identities = 222/222 (100%), Positives = 222/222 (100%)

Query: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60
           MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE
Sbjct: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60

Query: 61  SKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           SKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKE
Sbjct: 61  SKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKE 120

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVT 180
           GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVT
Sbjct: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVT 180

Query: 181 DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLARGA 222
           DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLARGA
Sbjct: 181 DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLARGA 222


>tr|A3Q6W2|A3Q6W2_MYCSJ Tax_Id=164757 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium sp.]
          Length = 221

 Score =  336 bits (861), Expect = 1e-90
 Identities = 173/219 (78%), Positives = 194/219 (88%), Gaps = 1/219 (0%)

Query: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60
           M TVAVVPAAGSG+RL AG PKAFV L G P+LE A++GLR SGV+D IV+AVPP+ TDE
Sbjct: 1   MTTVAVVPAAGSGQRLAAGAPKAFVNLAGRPMLERAIAGLRDSGVVDSIVVAVPPSRTDE 60

Query: 61  SKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           +KLVFGGE ++IV+GG DRTESV+LAL A GDA++VLVHDAARALTPP+L+ARVV AL+ 
Sbjct: 61  AKLVFGGE-ALIVAGGADRTESVSLALAAVGDADYVLVHDAARALTPPSLVARVVRALEA 119

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVT 180
           GHSAVVPGL  ADTIKAVDANGAVLGTPERAGLRA+QTPQGFH DVLRRAYARA  GG T
Sbjct: 120 GHSAVVPGLPVADTIKAVDANGAVLGTPERAGLRAIQTPQGFHIDVLRRAYARAGDGGFT 179

Query: 181 DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLA 219
           DDAS+VEQ G  VQ+VDGDPLAFKITTPLDLVLAEA+LA
Sbjct: 180 DDASMVEQAGGQVQVVDGDPLAFKITTPLDLVLAEAILA 218


>tr|Q1B2P1|Q1B2P1_MYCSS Tax_Id=164756 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; Flags:
           Precursor;[Mycobacterium sp.]
          Length = 221

 Score =  332 bits (850), Expect = 3e-89
 Identities = 171/219 (78%), Positives = 192/219 (87%), Gaps = 1/219 (0%)

Query: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60
           M TVAVVPAAGSG+RL AG PKAFV L G P+LE A++GLR SGV+D IV+AVPP+ TDE
Sbjct: 1   MTTVAVVPAAGSGQRLAAGAPKAFVNLAGRPMLERAIAGLRNSGVVDSIVVAVPPSRTDE 60

Query: 61  SKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           +KLVFGGE ++IV+GG DRTESV  AL A GDA++VLVHDAARALTPP+L+ARVV AL+ 
Sbjct: 61  AKLVFGGE-ALIVAGGADRTESVRAALAAVGDADYVLVHDAARALTPPSLVARVVRALEA 119

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVT 180
           GHSAVVPGL  ADTIKAVDANGAVLGTPERAGLRA+QTPQGFH DVLRRAYARA  GG T
Sbjct: 120 GHSAVVPGLPVADTIKAVDANGAVLGTPERAGLRAIQTPQGFHIDVLRRAYARAGDGGFT 179

Query: 181 DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLA 219
           DDAS+VEQ G  VQ+V+GDPLAFKITTPLDLVLAEA+LA
Sbjct: 180 DDASMVEQAGGQVQVVEGDPLAFKITTPLDLVLAEAILA 218


>tr|A1UMF7|A1UMF7_MYCSK Tax_Id=189918 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium sp.]
          Length = 221

 Score =  332 bits (850), Expect = 3e-89
 Identities = 171/219 (78%), Positives = 192/219 (87%), Gaps = 1/219 (0%)

Query: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60
           M TVAVVPAAGSG+RL AG PKAFV L G P+LE A++GLR SGV+D IV+AVPP+ TDE
Sbjct: 1   MTTVAVVPAAGSGQRLAAGAPKAFVNLAGRPMLERAIAGLRNSGVVDSIVVAVPPSRTDE 60

Query: 61  SKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           +KLVFGGE ++IV+GG DRTESV  AL A GDA++VLVHDAARALTPP+L+ARVV AL+ 
Sbjct: 61  AKLVFGGE-ALIVAGGADRTESVRAALAAVGDADYVLVHDAARALTPPSLVARVVRALEA 119

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVT 180
           GHSAVVPGL  ADTIKAVDANGAVLGTPERAGLRA+QTPQGFH DVLRRAYARA  GG T
Sbjct: 120 GHSAVVPGLPVADTIKAVDANGAVLGTPERAGLRAIQTPQGFHIDVLRRAYARAGDGGFT 179

Query: 181 DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLA 219
           DDAS+VEQ G  VQ+V+GDPLAFKITTPLDLVLAEA+LA
Sbjct: 180 DDASMVEQAGGQVQVVEGDPLAFKITTPLDLVLAEAILA 218


>tr|D5P8L1|D5P8L1_9MYCO Tax_Id=525368 (ispD)SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium
           parascrofulaceum ATCC BAA-614]
          Length = 228

 Score =  272 bits (695), Expect = 2e-71
 Identities = 149/216 (68%), Positives = 169/216 (78%), Gaps = 2/216 (0%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VAVVPAAGSGERL AG PKAF  + G  LL+ A+ GL  SGV+DR+V+AVP A  DE+K 
Sbjct: 12  VAVVPAAGSGERLGAGIPKAFCEVAGRTLLDRAVEGLLESGVVDRVVVAVPAARIDEAKR 71

Query: 64  VFGGEDSVIVSGGVDRTESVALALEA-AGDAEFVLVHDAARALTPPALIARVVAALKEGH 122
             G E + +V+GG DRT SV+LAL A AGD  FVLVHDAARALTPPAL+ RVV AL+ GH
Sbjct: 72  ALG-ERATVVAGGADRTTSVSLALAALAGDPGFVLVHDAARALTPPALVVRVVDALRSGH 130

Query: 123 SAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDD 182
           +AVVP L   DTIKAVDANG VLGTPERAGLRAVQTPQGF  ++L RAY RA     TDD
Sbjct: 131 NAVVPALPLHDTIKAVDANGVVLGTPERAGLRAVQTPQGFARELLLRAYQRAGTADFTDD 190

Query: 183 ASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
           ASLVE +G  VQ+VDGDPLAFKITT LDL+LAEAV+
Sbjct: 191 ASLVEHVGGQVQVVDGDPLAFKITTRLDLLLAEAVV 226


>sp|Q743W5|ISPD_MYCPA Tax_Id=1770 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium paratuberculosis]
          Length = 235

 Score =  257 bits (656), Expect = 8e-67
 Identities = 142/218 (65%), Positives = 165/218 (75%), Gaps = 3/218 (1%)

Query: 5   AVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLV 64
           AVVPAAGSGERL AG PKAF  + G  +L  A++GL  S V+D +V+AVP    DE+K +
Sbjct: 19  AVVPAAGSGERLAAGIPKAFCEIDGASMLARAVAGLLDSKVVDHVVVAVPADRVDEAKRL 78

Query: 65  FGGEDSVIVSGGVDRTESVALALEAA-GDAEFVLVHDAARALTPPALIARVVAALKEGHS 123
             G+ + +V+GG DRT SV LAL A  G+  FVLVHDAARALTPPALIARVV AL++GH 
Sbjct: 79  LPGQ-ATVVAGGADRTASVRLALAAVPGNPAFVLVHDAARALTPPALIARVVQALRDGHR 137

Query: 124 AVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYAR-ATAGGVTDD 182
           AVVP L   DT+KAVDANG VLGTPER GLRAVQTPQGF  D+L RAYA  A   G TDD
Sbjct: 138 AVVPALPLHDTVKAVDANGVVLGTPERDGLRAVQTPQGFATDLLLRAYAAGAGTAGFTDD 197

Query: 183 ASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAR 220
           ASLVE +G  VQ+VDGDPLAFKITT LDL+LAE ++ R
Sbjct: 198 ASLVEHVGGQVQVVDGDPLAFKITTQLDLLLAETIVRR 235


>tr|A0QAB3|A0QAB3_MYCA1 Tax_Id=243243 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium avium]
          Length = 229

 Score =  257 bits (656), Expect = 8e-67
 Identities = 142/221 (64%), Positives = 165/221 (74%), Gaps = 3/221 (1%)

Query: 2   ATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDES 61
           A  AVVPAAGSGERL AG PKAF  + G  +L  A++GL  S V+D +V+AVP    DE+
Sbjct: 10  AVAAVVPAAGSGERLAAGIPKAFCEIDGASMLARAVAGLLDSKVVDHVVVAVPADRVDEA 69

Query: 62  KLVFGGEDSVIVSGGVDRTESVALALEAA-GDAEFVLVHDAARALTPPALIARVVAALKE 120
           K +   + + +V+GG DRT SV LAL A  G+  FVLVHDAARALTPPALIARVV AL++
Sbjct: 70  KRLLAAQ-ATVVAGGADRTASVRLALAAVPGNPAFVLVHDAARALTPPALIARVVQALRD 128

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYAR-ATAGGV 179
           GH AVVP L   DT+KAVDANG VLGTPER GLRAVQTPQGF  D+L RAYA  A   G 
Sbjct: 129 GHRAVVPALPLHDTVKAVDANGVVLGTPERDGLRAVQTPQGFATDLLLRAYAAGAGTAGF 188

Query: 180 TDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAR 220
           TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LAE ++ R
Sbjct: 189 TDDASLVEHVGGQVQVVDGDPLAFKITTQLDLLLAETIVRR 229


>sp|A0PV29|ISPD_MYCUA Tax_Id=362242 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium ulcerans]
          Length = 227

 Score =  256 bits (654), Expect = 1e-66
 Identities = 140/217 (64%), Positives = 162/217 (74%), Gaps = 4/217 (1%)

Query: 5   AVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLV 64
           A+VPAAGSG+RL AG PKAF  L G  L+E A+ GL  SGV+D +V+AVPP  TDE+KL+
Sbjct: 10  AIVPAAGSGQRLAAGVPKAFYQLEGQTLVERAVRGLFESGVVDTVVVAVPPDRTDEAKLI 69

Query: 65  FGGEDSVIVSGGVDRTESVALALEAAG---DAEFVLVHDAARALTPPALIARVVAALKEG 121
            G E + IV+GG DRTESV+ AL A       EFVLVHDAARALTPPAL+ R+V  L+ G
Sbjct: 70  LGRE-ATIVAGGADRTESVSRALSALSAGVSPEFVLVHDAARALTPPALVVRLVDMLRAG 128

Query: 122 HSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTD 181
           H+AVVP L   DTIKAVDANG VLGTPERAGLRAVQTPQGF  ++L RAY  A     TD
Sbjct: 129 HAAVVPVLPLTDTIKAVDANGVVLGTPERAGLRAVQTPQGFSTELLLRAYRHAGVSAFTD 188

Query: 182 DASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
           DASLVE +G  V +V GDPLAFKIT  LDL+LA AV+
Sbjct: 189 DASLVEHVGGQVHVVGGDPLAFKITNRLDLLLAHAVV 225


>sp|B2HJ23|ISPD_MYCMM Tax_Id=216594 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium marinum]
          Length = 227

 Score =  256 bits (654), Expect = 1e-66
 Identities = 140/217 (64%), Positives = 162/217 (74%), Gaps = 4/217 (1%)

Query: 5   AVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLV 64
           A+VPAAGSG+RL AG PKAF  L G  L+E A+ GL  SGV+D +V+AVPP  TDE+KL+
Sbjct: 10  AIVPAAGSGQRLAAGVPKAFYQLEGQTLVERAVRGLLESGVVDTVVVAVPPDRTDEAKLI 69

Query: 65  FGGEDSVIVSGGVDRTESVALALEAAG---DAEFVLVHDAARALTPPALIARVVAALKEG 121
            G E + IV+GG DRTESV+ AL A       EFVLVHDAARALTPPAL+ R+V  L+ G
Sbjct: 70  LGRE-ATIVAGGADRTESVSRALSALSAGVSPEFVLVHDAARALTPPALVVRLVDMLRAG 128

Query: 122 HSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTD 181
           H+AVVP L   DTIKAVDANG VLGTPERAGLRAVQTPQGF  ++L RAY  A     TD
Sbjct: 129 HAAVVPVLPLTDTIKAVDANGVVLGTPERAGLRAVQTPQGFSTELLLRAYRHAGVAAFTD 188

Query: 182 DASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
           DASLVE +G  V +V GDPLAFKIT  LDL+LA AV+
Sbjct: 189 DASLVEHVGGQVHVVAGDPLAFKITNRLDLLLAHAVV 225


>tr|D5YL32|D5YL32_MYCTU Tax_Id=520140 SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Mycobacterium tuberculosis EAS054]
          Length = 231

 Score =  255 bits (651), Expect = 3e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGLPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>sp|P96864|ISPD_MYCTU Tax_Id=1773 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium tuberculosis]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>sp|A5U8Q7|ISPD_MYCTA Tax_Id=419947 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium tuberculosis]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>sp|C1AI41|ISPD_MYCBT Tax_Id=561275 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium bovis]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>sp|A1KPR8|ISPD_MYCBP Tax_Id=410289 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium bovis]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>sp|Q7TW54|ISPD_MYCBO Tax_Id=1765 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium bovis]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALAVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|C6DMN4|C6DMN4_MYCTK Tax_Id=478434 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium
           tuberculosis]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|A5WTF1|A5WTF1_MYCTF Tax_Id=336982 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium
           tuberculosis]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D6G4S2|D6G4S2_MYCTU Tax_Id=478435 SubName:
           Full=4-diphosphocytidyl-2-C-methyl-D-erythritol synthase
           ispD;[Mycobacterium tuberculosis KZN 605]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D6FT65|D6FT65_MYCTU Tax_Id=611304 SubName:
           Full=4-diphosphocytidyl-2-C-methyl-D-erythritol synthase
           ispD;[Mycobacterium tuberculosis K85]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D6FHJ2|D6FHJ2_MYCTU Tax_Id=611303 SubName:
           Full=4-diphosphocytidyl-2-C-methyl-D-erythritol synthase
           ispD;[Mycobacterium tuberculosis CPHL_A]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D6EYT0|D6EYT0_MYCTU Tax_Id=611302 SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Mycobacterium tuberculosis T46]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D5ZMC6|D5ZMC6_MYCTU Tax_Id=537210 SubName:
           Full=4-diphosphocytidyl-2-C-methyl-D-erythritol synthase
           ispD;[Mycobacterium tuberculosis T17]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D5ZAF6|D5ZAF6_MYCTU Tax_Id=537209 SubName:
           Full=4-diphosphocytidyl-2-C-methyl-D-erythritol synthase
           ispD;[Mycobacterium tuberculosis GM 1503]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D5YXK3|D5YXK3_MYCTU Tax_Id=515616 SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Mycobacterium tuberculosis
           02_1987]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D5Y9I2|D5Y9I2_MYCTU Tax_Id=520141 SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Mycobacterium tuberculosis T85]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|D5XZS3|D5XZS3_MYCTU Tax_Id=515617 SubName:
           Full=4-diphosphocytidyl-2-C-methyl-D-erythritol synthase
           ispD;[Mycobacterium tuberculosis T92]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|A4KM67|A4KM67_MYCTU Tax_Id=395095 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium
           tuberculosis str. Haarlem]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>tr|A2VPZ0|A2VPZ0_MYCTU Tax_Id=348776 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Mycobacterium
           tuberculosis C]
          Length = 231

 Score =  254 bits (650), Expect = 4e-66
 Identities = 139/222 (62%), Positives = 170/222 (76%), Gaps = 8/222 (3%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAGSGERL  G PKAF  L G  L+E A+ GL  SGV+D +V+AVP   TDE++ 
Sbjct: 9   VAIVPAAGSGERLAVGVPKAFYQLDGQTLIERAVDGLLDSGVVDTVVVAVPADRTDEARQ 68

Query: 64  VFGGEDSVIVSGGVDRTESVALAL---EAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           + G   ++IV+GG +RT++V LAL       + EFVLVHDAARALTPPAL+ARVV AL++
Sbjct: 69  ILGHR-AMIVAGGSNRTDTVNLALTVLSGTAEPEFVLVHDAARALTPPALVARVVEALRD 127

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARAT----A 176
           G++AVVP L  +DTIKAVDANG VLGTPERAGLRAVQTPQGF  D+L R+Y R +    A
Sbjct: 128 GYAAVVPVLPLSDTIKAVDANGVVLGTPERAGLRAVQTPQGFTTDLLLRSYQRGSLDLPA 187

Query: 177 GGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
              TDDASLVE +G  VQ+VDGDPLAFKITT LDL+LA+A++
Sbjct: 188 AEYTDDASLVEHIGGQVQVVDGDPLAFKITTKLDLLLAQAIV 229


>sp|C0ZPR7|ISPD_RHOE4 Tax_Id=234621 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Rhodococcus erythropolis]
          Length = 232

 Score =  244 bits (622), Expect = 7e-63
 Identities = 140/221 (63%), Positives = 158/221 (71%), Gaps = 6/221 (2%)

Query: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60
           MA VA+VPAAG G RL    PKAFV LGG  +L  A+ GLR SG IDR+V+ VPP L + 
Sbjct: 1   MAVVALVPAAGRGVRLGEKLPKAFVELGGCTMLARAVDGLRKSGAIDRVVVIVPPELVES 60

Query: 61  SKLVFGGEDSV-IVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALK 119
                G    V +V GG +RT+SV   L AAGDA+FVLVHDAARALTPPALIARVV AL+
Sbjct: 61  VVADLGRASDVDVVGGGAERTDSVRAGLSAAGDADFVLVHDAARALTPPALIARVVDALR 120

Query: 120 EGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGV 179
            G SAV+P L   DTIK+VD  GAV GTP R+ LRAVQTPQGF  DVLR AY    AG V
Sbjct: 121 AGSSAVIPVLPVTDTIKSVDVLGAVTGTPLRSELRAVQTPQGFSTDVLRSAY---DAGDV 177

Query: 180 --TDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVL 218
             TDDA+LVE+LG  VQ + GD LAFKITTPLDLVLA A+L
Sbjct: 178 AATDDAALVERLGVSVQTIPGDALAFKITTPLDLVLARALL 218


>tr|C3JUM9|C3JUM9_RHOER Tax_Id=596309 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Rhodococcus
           erythropolis SK121]
          Length = 232

 Score =  242 bits (618), Expect = 2e-62
 Identities = 139/222 (62%), Positives = 158/222 (71%), Gaps = 6/222 (2%)

Query: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60
           MA VA+VPAAG G RL    PKAFV LGG  +L  A+ GLR SG IDR+V+ VPP L + 
Sbjct: 1   MAVVALVPAAGRGVRLGEKLPKAFVELGGCTMLARAVDGLRKSGAIDRVVVIVPPELVES 60

Query: 61  SKLVFG-GEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALK 119
                G   D  +V GG +RT+SV   L AAGDA+FVLVHDAARALTPPALIARVV  L+
Sbjct: 61  VVADLGRAADVDVVGGGAERTDSVRAGLSAAGDADFVLVHDAARALTPPALIARVVDTLR 120

Query: 120 EGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGV 179
            G SAV+P L   DTIK+VD  GAV GTP R+ LRAVQTPQGF  DVLR AY    AG V
Sbjct: 121 AGSSAVIPVLPVTDTIKSVDVLGAVTGTPLRSELRAVQTPQGFSTDVLRSAY---DAGDV 177

Query: 180 --TDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLA 219
             TDDA+LVE+LG  VQ + GD LAFKITTPLDLVLA A+L+
Sbjct: 178 AATDDAALVERLGVSVQTIPGDALAFKITTPLDLVLARALLS 219


>sp|Q0S890|ISPD_RHOSR Tax_Id=101510 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Rhodococcus sp.]
          Length = 226

 Score =  240 bits (612), Expect = 1e-61
 Identities = 132/219 (60%), Positives = 161/219 (73%), Gaps = 2/219 (0%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAG G RL   RPKAFV LGGT +L  A+ GL  SG +DR+V+ VP  L + ++ 
Sbjct: 9   VALVPAAGQGVRLGENRPKAFVDLGGTTMLTRAVDGLLQSGAVDRVVVIVPEELVESTRT 68

Query: 64  VFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKEGHS 123
           +  GE +V V+GG +RT+SV   L  A DA++VLVHDAARALTPP+LIARVV  L+ G +
Sbjct: 69  LLPGEVTV-VAGGSERTDSVRAGLAVADDADYVLVHDAARALTPPSLIARVVEELRCGRN 127

Query: 124 AVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDA 183
           AV+P L   DTIK VD  GAV GTPER+ LRAVQTPQGF A++LRRAYA A  G  TDDA
Sbjct: 128 AVIPVLPVTDTIKTVDVLGAVTGTPERSELRAVQTPQGFTAELLRRAYA-AADGIATDDA 186

Query: 184 SLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLARGA 222
            LVE+LG  V+ + G+P AFKITTPLDLVLA A++  GA
Sbjct: 187 GLVERLGERVRSIVGEPTAFKITTPLDLVLARALVEEGA 225


>sp|C1BAC2|ISPD_RHOOB Tax_Id=632772 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Rhodococcus opacus]
          Length = 226

 Score =  239 bits (609), Expect = 2e-61
 Identities = 133/219 (60%), Positives = 160/219 (73%), Gaps = 2/219 (0%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VA+VPAAG G RL   +PKAFV LGGT +L  A+ GL  SG +DR+V+ VP  L + ++ 
Sbjct: 9   VALVPAAGQGVRLGENKPKAFVDLGGTTMLTRAVDGLLQSGAVDRVVVIVPEELVESTRS 68

Query: 64  VFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKEGHS 123
           +  G  +V V+GG +RT SV   L  A DAE+VLVHDAARALTPP+LIARVVA L+ G  
Sbjct: 69  LLPGHVTV-VAGGSERTGSVRAGLAVADDAEYVLVHDAARALTPPSLIARVVAELRCGRR 127

Query: 124 AVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDA 183
           AV+P L  ADTIK VD  GAV GTPER+ LRAVQTPQGF A++LRRAYA A  G  TDDA
Sbjct: 128 AVIPVLPVADTIKTVDVLGAVTGTPERSELRAVQTPQGFTAELLRRAYA-AADGIATDDA 186

Query: 184 SLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLARGA 222
            LVE+LG  V+ + G+P AFKITTPLDLVLA A++  GA
Sbjct: 187 GLVERLGERVRSIVGEPTAFKITTPLDLVLARALVEEGA 225


>sp|Q5Z2R3|ISPD_NOCFA Tax_Id=37329 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Nocardia farcinica]
          Length = 230

 Score =  233 bits (594), Expect = 1e-59
 Identities = 129/222 (58%), Positives = 155/222 (69%), Gaps = 3/222 (1%)

Query: 2   ATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDES 61
           + VA+VPAAG G RL    PKAFV +GGTP++  A+ GL A+GV+DRI++ VP    + +
Sbjct: 9   SVVALVPAAGRGVRLGEKSPKAFVPVGGTPMVRLAVDGLLAAGVVDRIIVMVPAEWVESA 68

Query: 62  KLVFGGEDSV-IVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
             +    + V +V GG +RT+SV   L AA DA + LVHDAARALTPPALI R+V  L+ 
Sbjct: 69  VALLPPSEVVRVVVGGAERTDSVRAGLAAAPDAGYFLVHDAARALTPPALIGRIVGELRA 128

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVT 180
           G  AVVP L   DT+K+VDA G V GTP+RA LRAVQTPQGF AD+LR AYA       T
Sbjct: 129 GRRAVVPALPVVDTVKSVDAAGVVTGTPDRAALRAVQTPQGFTADLLRAAYAADVP--AT 186

Query: 181 DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLARGA 222
           DDA LVE+LG PV  V GDPLAFKITTPLDL LAE +L R A
Sbjct: 187 DDAGLVERLGEPVHTVAGDPLAFKITTPLDLRLAETLLDRRA 228


>sp|Q9CCW6|ISPD_MYCLE Tax_Id=1769 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium leprae]
          Length = 241

 Score =  230 bits (587), Expect = 8e-59
 Identities = 134/233 (57%), Positives = 159/233 (68%), Gaps = 16/233 (6%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VAVVPAAG+G+RL AG PKAF  L G  L+E A+ GL  SGV+D +V+AVP     +++ 
Sbjct: 9   VAVVPAAGAGKRLAAGIPKAFCELDGRTLVERAVVGLLESGVVDHVVVAVPADRIAQTQW 68

Query: 64  VFG-------GEDSVIVSGGVDRTESVALALEA------AGDAEFVLVHDAARALTPPAL 110
           V         G+ + +V+GG DRT+SV  AL         G  EF+LVHDAARALTP  L
Sbjct: 69  VLSQRLANSAGQHATVVAGGADRTKSVCQALATLPAPSRVGAPEFILVHDAARALTPARL 128

Query: 111 IARVVAALKEGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRA 170
           I RVV AL+ GH+AVVP L  +DTIKAVDANG VLGTP R GLRAVQTPQGF  ++L  A
Sbjct: 129 IVRVVDALRAGHTAVVPALPLSDTIKAVDANGMVLGTPARVGLRAVQTPQGFATELLWCA 188

Query: 171 YARA---TAGGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAR 220
           Y R     A   TDDASLVE LG  VQ+V GDPLAFKITT LDL+LA+ +L R
Sbjct: 189 YQRGPHLDAVDFTDDASLVEHLGGQVQVVAGDPLAFKITTQLDLLLAKKILRR 241


>sp|B8ZUA7|ISPD_MYCLB Tax_Id=561304 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Mycobacterium leprae]
          Length = 241

 Score =  230 bits (587), Expect = 8e-59
 Identities = 134/233 (57%), Positives = 159/233 (68%), Gaps = 16/233 (6%)

Query: 4   VAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKL 63
           VAVVPAAG+G+RL AG PKAF  L G  L+E A+ GL  SGV+D +V+AVP     +++ 
Sbjct: 9   VAVVPAAGAGKRLAAGIPKAFCELDGRTLVERAVVGLLESGVVDHVVVAVPADRIAQTQW 68

Query: 64  VFG-------GEDSVIVSGGVDRTESVALALEA------AGDAEFVLVHDAARALTPPAL 110
           V         G+ + +V+GG DRT+SV  AL         G  EF+LVHDAARALTP  L
Sbjct: 69  VLSQRLANSAGQHATVVAGGADRTKSVCQALATLPAPSRVGAPEFILVHDAARALTPARL 128

Query: 111 IARVVAALKEGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRA 170
           I RVV AL+ GH+AVVP L  +DTIKAVDANG VLGTP R GLRAVQTPQGF  ++L  A
Sbjct: 129 IVRVVDALRAGHTAVVPALPLSDTIKAVDANGMVLGTPARVGLRAVQTPQGFATELLWCA 188

Query: 171 YARA---TAGGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAR 220
           Y R     A   TDDASLVE LG  VQ+V GDPLAFKITT LDL+LA+ +L R
Sbjct: 189 YQRGPHLDAVDFTDDASLVEHLGGQVQVVAGDPLAFKITTQLDLLLAKKILRR 241


>tr|D5USV3|D5USV3_TSUPA Tax_Id=521096 SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Tsukamurella paurometabola DSM
           20162]
          Length = 220

 Score =  223 bits (567), Expect = 2e-56
 Identities = 126/217 (58%), Positives = 147/217 (67%), Gaps = 2/217 (0%)

Query: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60
           M  VA+VPAAG G RL   RPKAFVTL G  LLE A+ GL ASG +D +V+ VP  L D+
Sbjct: 1   MTVVALVPAAGQGTRLGLNRPKAFVTLQGRSLLERAVDGLFASGAVDEVVVMVPADLVDD 60

Query: 61  SKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKE 120
           ++ +     + +V GG +RT+SV   L AAGDA+ VLVHDAAR LTP  +I RVVAAL+E
Sbjct: 61  ARALV--PRARVVVGGAERTDSVRAGLAAAGDADLVLVHDAARPLTPGPMIHRVVAALRE 118

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVT 180
           G SAV+P L  ADTIK VDA GAV  T +RA LRAVQTPQGF A  LR AY  A     T
Sbjct: 119 GASAVIPVLPVADTIKRVDAGGAVAATVDRADLRAVQTPQGFTAQALRAAYDAAPNESAT 178

Query: 181 DDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAV 217
           DDA LVE+ G  V  V GDPLA KITT  DL +AE +
Sbjct: 179 DDAGLVERAGGTVATVTGDPLAMKITTAFDLRIAEVL 215


>tr|B1MGY3|B1MGY3_MYCA9 Tax_Id=561007 SubName: Full=Putative
           2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Mycobacterium abscessus]
          Length = 210

 Score =  216 bits (549), Expect = 2e-54
 Identities = 113/204 (55%), Positives = 147/204 (72%), Gaps = 2/204 (0%)

Query: 15  RLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLVFGGEDSVIVS 74
           RL A  PKAFV++GG  +L+  + GL ASG +D +V+ V     + +  + G   + +V 
Sbjct: 2   RLGANTPKAFVSVGGRTMLQRCVDGLLASGAVDEVVVVVGADQLERAAALVGS-GATVVQ 60

Query: 75  GGVDRTESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKEGHSAVVPGLAPADT 134
           GG +RT+SV   L A   A+++LVHDAAR LTPP +IAR+VA L+ G  AV+P +A ADT
Sbjct: 61  GGAERTDSVRAGLAAVDAADWILVHDAARPLTPPDMIARIVAELRTGRGAVIPAVAVADT 120

Query: 135 IKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDASLVEQLGTPVQ 194
           IK++D +G V+GTP+RAGLRAVQTPQGF ADVLRRAYA A     TDDA+LVEQ+G  V 
Sbjct: 121 IKSIDVHGDVIGTPDRAGLRAVQTPQGFAADVLRRAYA-AAGDIATDDAALVEQIGERVH 179

Query: 195 IVDGDPLAFKITTPLDLVLAEAVL 218
           +V+GD LAFKITT LD+ LAEA+L
Sbjct: 180 VVEGDRLAFKITTTLDMTLAEAIL 203


>sp|Q2J542|ISPD_FRASC Tax_Id=106370 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60; AltName:
           Full=4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
           AltName: Full=MEP cytidylyltransferase;
           Short=MCT;[Frankia sp.]
          Length = 266

 Score =  212 bits (540), Expect = 2e-53
 Identities = 119/217 (54%), Positives = 143/217 (65%), Gaps = 3/217 (1%)

Query: 5   AVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLV 64
           A+VPAAG GERL  G PKA   LGG P+L   +  LR S ++ +IV+A PP L D    +
Sbjct: 16  AIVPAAGRGERLGGGTPKALRALGGRPMLVRTVESLRRSRLVTQIVVAAPPTLVDAVAQL 75

Query: 65  FGGEDSVIVSGGVDRTESVALALEAAGD-AEFVLVHDAARALTPPALIARVVAALKEGHS 123
            GG D  +++GG +R +SV  AL A  D    VLVHDAAR LTPP L+  V AA+ +GH 
Sbjct: 76  LGG-DVYVIAGGAERVDSVRRALRAVDDDVSVVLVHDAARPLTPPELVDAVAAAVLDGHP 134

Query: 124 AVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDA 183
           AV+P +  ADT+K VDA+G V+ TP R GLRAVQTPQGF  DVL  AYA      VTDDA
Sbjct: 135 AVIPVVPLADTVKEVDADGRVVRTPPRDGLRAVQTPQGFRRDVLSAAYALEDI-AVTDDA 193

Query: 184 SLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAR 220
            LVE LG PV  + G   AFK+T P DLVLAEA+LAR
Sbjct: 194 GLVEALGVPVTTIPGAQEAFKVTRPADLVLAEALLAR 230


>tr|D1V792|D1V792_9ACTO Tax_Id=298654 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Frankia sp. EuI1c]
          Length = 235

 Score =  208 bits (529), Expect = 4e-52
 Identities = 120/218 (55%), Positives = 147/218 (67%), Gaps = 5/218 (2%)

Query: 6   VVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE-SKLV 64
           VVPAAG GERL  G PKA   LGG P+L HA+  L A+ ++ +IV+A PP L +  S+L+
Sbjct: 11  VVPAAGRGERLGGGVPKALRPLGGRPMLVHAVQALAAADLVSQIVVAAPPTLVEVVSRLL 70

Query: 65  FGGEDSVIVSGGVDRTESVALALEAAGD-AEFVLVHDAARALTPPALIARVVAALKEGHS 123
             G D  +++GG +R +SV  AL A  D    VLVHDAAR LTPP+L+  V AA+  G  
Sbjct: 71  --GPDVRVLAGGAERVDSVRGALRALDDDIRVVLVHDAARPLTPPSLVDAVAAAVLGGQP 128

Query: 124 AVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAG-GVTDD 182
           AV+P L  ADT+K VDA G VL TP R GLRAVQTPQGF  +VL  AYA +  G  VTDD
Sbjct: 129 AVIPVLPVADTVKEVDAQGRVLRTPTRDGLRAVQTPQGFRREVLEAAYANSDDGPAVTDD 188

Query: 183 ASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAR 220
           A LVE+LG PV  + G   AFK+T P+DLV AEA+LAR
Sbjct: 189 AGLVERLGVPVTTIPGAEEAFKVTRPIDLVFAEALLAR 226


>tr|D5PZ30|D5PZ30_COREQ Tax_Id=525370 (ispD)SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Rhodococcus equi ATCC
           33707]
          Length = 203

 Score =  201 bits (512), Expect = 4e-50
 Identities = 113/200 (56%), Positives = 137/200 (68%), Gaps = 2/200 (1%)

Query: 21  PKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLVFGGEDSVIVSGGVDRT 80
           PKAFV LGG  +L  A+ GL  SGV+D +V+ VP  L + ++        V+V GG +R 
Sbjct: 2   PKAFVELGGRSMLRRAVDGLLGSGVVDTVVVIVPDELVEAARADLPAGVLVVV-GGEERA 60

Query: 81  ESVALALEAAGDAEFVLVHDAARALTPPALIARVVAALKEGHSAVVPGLAPADTIKAVDA 140
           +SV   L AA +A  VLVHDAARALTPP+LIARVVA L+ G +AVVP L  +DTIK VD 
Sbjct: 61  DSVRAGLAAAPEAGLVLVHDAARALTPPSLIARVVAELQAGRTAVVPVLPVSDTIKTVDV 120

Query: 141 NGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDASLVEQLGTPVQIVDGDP 200
            G V GTP R+ LRAVQTPQGF AD+LRRAY     G  TDDA LVE+LG PV+ + G+P
Sbjct: 121 LGTVTGTPPRSELRAVQTPQGFDADLLRRAYEDVN-GDATDDAGLVERLGEPVRTIVGEP 179

Query: 201 LAFKITTPLDLVLAEAVLAR 220
            AFKITTP DL LA  +L +
Sbjct: 180 EAFKITTPWDLALARVLLGQ 199


>tr|D3DC67|D3DC67_9ACTO Tax_Id=102897 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Frankia sp. EUN1f]
          Length = 229

 Score =  198 bits (503), Expect = 4e-49
 Identities = 115/216 (53%), Positives = 139/216 (64%), Gaps = 3/216 (1%)

Query: 5   AVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLV 64
           AVVPAAG GERL  G PKA   L G P+L  A+  L +S ++ ++V+A PP L D    +
Sbjct: 7   AVVPAAGRGERLGGGTPKALRPLAGRPMLLRAVETLLSSTLVSQVVVAAPPTLVDVVGQL 66

Query: 65  FGGEDSVIVSGGVDRTESVALALEAAGD-AEFVLVHDAARALTPPALIARVVAALKEGHS 123
            G    V V GG +R +SV +AL+A  D    VLVHDAAR LTP  L+  V   + +GH 
Sbjct: 67  LGSGVRV-VPGGAERVDSVRVALDALDDDIGVVLVHDAARPLTPAKLVDAVATTVLDGHP 125

Query: 124 AVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDA 183
           AV+P L  ADTIK +DA+G V+ TP R GLRAVQTPQGF  D+LR AYA      VTDDA
Sbjct: 126 AVIPVLPVADTIKEIDADGRVVRTPRRDGLRAVQTPQGFRRDILRAAYANRDL-PVTDDA 184

Query: 184 SLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLA 219
            LVE LG PV  + G   AFK+T P DLVLAEA+LA
Sbjct: 185 GLVEALGVPVTTIPGAEEAFKVTRPADLVLAEALLA 220


>tr|C6WGL6|C6WGL6_ACTMD Tax_Id=446462 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Actinosynnema mirum]
          Length = 230

 Score =  196 bits (499), Expect = 1e-48
 Identities = 115/230 (50%), Positives = 143/230 (62%), Gaps = 11/230 (4%)

Query: 1   MATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDE 60
           M  VA+VPAAG GERL  G PKA V +GG PLL  A+ GL  SG +  +V+A PP+  D+
Sbjct: 1   MGVVALVPAAGRGERLGFGMPKALVPVGGVPLLVRAIRGLFESGRVRHVVVAAPPSDVDQ 60

Query: 61  SKLVFG-----GEDSVIVSGGVDRTESVALALEAA----GDAEFVLVHDAARALTPPALI 111
            + V       G    +++GG +R++SV LALE A     D   VLVHDAARA TPP ++
Sbjct: 61  VRTVTAPLAPAGGAVHVLAGGAERSDSVRLALEHALAEVPDVRVVLVHDAARAFTPPTVV 120

Query: 112 ARVVAALKEGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAY 171
             VV A+  GH AV+P L  ADT+K VD  G V+ TP+R+ LR VQTPQGF A  LR A+
Sbjct: 121 RDVVDAVLAGHPAVIPVLPVADTVKRVDTKGVVVDTPDRSLLRVVQTPQGFDAATLRAAH 180

Query: 172 ARATAGGVTDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLARG 221
                   TDDA LVE+LG PV  V G   A K+TTP DL +AEA+L  G
Sbjct: 181 ESGL--HATDDAGLVERLGVPVVTVTGHQDAMKVTTPFDLAVAEALLVGG 228


>tr|C7QIR9|C7QIR9_CATAD Tax_Id=479433 SubName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Catenulispora acidiphila]
          Length = 253

 Score =  195 bits (496), Expect = 3e-48
 Identities = 120/221 (54%), Positives = 146/221 (66%), Gaps = 7/221 (3%)

Query: 6   VVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPP---ALTDESK 62
           +VPAAG GERL  G PKA   LGG PLL HA+  L A+  +D +V+A PP    + +  +
Sbjct: 32  IVPAAGKGERLGPGAPKALRELGGLPLLVHAVRTLVAARSVDLVVVAAPPDPQGVAEVQR 91

Query: 63  LVFG-GEDSVIVSGGVDRTESVALALEAA-GDAEFVLVHDAARALTPPALIARVVAALKE 120
           L+     D+ +V+GG  R ESVALAL A   D + VLVHDAARALTP  +I  VVAA++ 
Sbjct: 92  LLADLPGDTRVVAGGTSRQESVALALAALPADCDVVLVHDAARALTPVEVIGAVVAAVRG 151

Query: 121 GHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARA-TAGGV 179
           G  AV+P L   DT+KAVD +  V  T +R+ LRAVQTPQGF  D+L +A+A A  A   
Sbjct: 152 GAGAVIPVLPVTDTVKAVDGD-LVTATVDRSTLRAVQTPQGFTRDILAKAHAAADPAAPA 210

Query: 180 TDDASLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLAR 220
           TDDA LVE LG PV+ V G   AFKITTP DLVLAEAVL R
Sbjct: 211 TDDAGLVEALGLPVRTVPGHAEAFKITTPFDLVLAEAVLRR 251


>tr|C7NK62|C7NK62_KYTSD Tax_Id=478801 SubName:
           Full=2C-methyl-D-erythritol 2,4-cyclodiphosphate
           synthase/2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase;[Kytococcus sedentarius]
          Length = 421

 Score =  192 bits (488), Expect = 2e-47
 Identities = 114/216 (52%), Positives = 133/216 (61%), Gaps = 10/216 (4%)

Query: 6   VVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLVF 65
           VV AAGSG RL AG PKAFV + G  LLEHAL GL AS  +  +V+  P    D +  + 
Sbjct: 15  VVVAAGSGTRLGAGLPKAFVEVDGATLLEHALDGLLASERVGEVVVVAPAGWEDLAAELL 74

Query: 66  GGEDS-------VIVSGGVDRTESVALALEAAGDA-EFVLVHDAARALTPPALIARVVAA 117
           G   S        +V+GG +R++SVA  L A  DA + VLVHDAAR  TPP +  RVV A
Sbjct: 75  GRAASCPCPHRTAVVTGGAERSDSVAAGLAALSDAVDLVLVHDAARCFTPPEVFGRVVDA 134

Query: 118 LKEGHSAVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAG 177
           ++ G +  VP L   DTIK VD    V GTP RA LRAVQTPQGF  +VL RA+A A   
Sbjct: 135 VRAGAAGAVPALPVVDTIKVVDDEDRVTGTPARASLRAVQTPQGFRREVLARAHAAAVGA 194

Query: 178 G--VTDDASLVEQLGTPVQIVDGDPLAFKITTPLDL 211
           G   TDDA LVEQLG PV  V GDP + KITTP DL
Sbjct: 195 GAAATDDALLVEQLGEPVVAVAGDPRSAKITTPADL 230


>tr|A8LF84|A8LF84_FRASN Tax_Id=298653 (ispD)RecName:
           Full=2-C-methyl-D-erythritol 4-phosphate
           cytidylyltransferase; EC=2.7.7.60;[Frankia sp.]
          Length = 229

 Score =  192 bits (488), Expect = 2e-47
 Identities = 113/219 (51%), Positives = 138/219 (63%), Gaps = 3/219 (1%)

Query: 5   AVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDESKLV 64
           A+VPAAG GERL  G PKA   LGG P+L  A+  L +S ++ ++V+A PP L +    +
Sbjct: 7   ALVPAAGRGERLGGGTPKALRPLGGRPMLLRAVETLLSSTLVSQVVVAAPPTLVEVVGQI 66

Query: 65  FGGEDSVIVSGGVDRTESVALALEAAGD-AEFVLVHDAARALTPPALIARVVAALKEGHS 123
            G    V V GG +R +SV  ALEA  D    VLVHDAAR LTP  L+  V   + +GH 
Sbjct: 67  LGPRVRV-VPGGAERVDSVRAALEALDDDIGVVLVHDAARPLTPAKLVDAVATTVLDGHP 125

Query: 124 AVVPGLAPADTIKAVDANGAVLGTPERAGLRAVQTPQGFHADVLRRAYARATAGGVTDDA 183
           AV+P L   DT+K VDA+G V+ TP R  LRAVQTPQGF  D+L  AYA      VTDDA
Sbjct: 126 AVIPVLPVTDTVKEVDADGRVVRTPPRDVLRAVQTPQGFRRDILHTAYANRDL-PVTDDA 184

Query: 184 SLVEQLGTPVQIVDGDPLAFKITTPLDLVLAEAVLARGA 222
            LVE LG PV  + G   AFK+T P DLVLAEA+LA+ A
Sbjct: 185 GLVEALGVPVTTIPGAEEAFKVTRPADLVLAEALLAQFA 223


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.317    0.134    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 1,799,192,422
Number of extensions: 75527728
Number of successful extensions: 258046
Number of sequences better than 10.0: 3661
Number of HSP's gapped: 258545
Number of HSP's successfully gapped: 3666
Length of query: 222
Length of database: 4,236,830,644
Length adjustment: 133
Effective length of query: 89
Effective length of database: 2,573,284,732
Effective search space: 229022341148
Effective search space used: 229022341148
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 78 (34.7 bits)