BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MSMEG_6271
         (602 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           12,507,864 sequences; 4,236,830,644 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|A0R5Q2|A0R5Q2_MYCS2 Tax_Id=246196 (leuA)SubName: Full=2-isopr...  1091   0.0  
tr|Q1B282|Q1B282_MYCSS Tax_Id=164756 SubName: Full=2-isopropylma...   956   0.0  
tr|A3Q7A2|A3Q7A2_MYCSJ Tax_Id=164757 SubName: Full=2-isopropylma...   956   0.0  
tr|A1UMW8|A1UMW8_MYCSK Tax_Id=189918 SubName: Full=2-isopropylma...   956   0.0  
tr|C3JNY6|C3JNY6_RHOER Tax_Id=596309 (leuA)SubName: Full=2-isopr...   946   0.0  
tr|C0ZN67|C0ZN67_RHOE4 Tax_Id=234621 (leuA)SubName: Full=2-isopr...   946   0.0  
tr|C1B9P5|C1B9P5_RHOOB Tax_Id=632772 (leuA)SubName: Full=2-isopr...   936   0.0  
tr|A4T617|A4T617_MYCGI Tax_Id=350054 SubName: Full=2-isopropylma...   936   0.0  
tr|Q0S8X0|Q0S8X0_RHOSR Tax_Id=101510 (leuA1)SubName: Full=2-isop...   932   0.0  
tr|A1TGI1|A1TGI1_MYCVP Tax_Id=350058 SubName: Full=2-isopropylma...   927   0.0  
tr|D5PKD7|D5PKD7_COREQ Tax_Id=525370 (leuA2)SubName: Full=2-isop...   911   0.0  
tr|A0Q9T9|A0Q9T9_MYCA1 Tax_Id=243243 (leuA)SubName: Full=2-isopr...   910   0.0  
tr|Q744M9|Q744M9_MYCPA Tax_Id=1770 (leuA)SubName: Full=LeuA;[Myc...   909   0.0  
tr|D0LDG8|D0LDG8_GORB4 Tax_Id=526226 SubName: Full=2-isopropylma...   907   0.0  
tr|Q5Z341|Q5Z341_NOCFA Tax_Id=37329 (leuA)SubName: Full=Putative...   906   0.0  
tr|D5P919|D5P919_9MYCO Tax_Id=525368 (leuA)SubName: Full=2-isopr...   900   0.0  
tr|D5UN64|D5UN64_TSUPA Tax_Id=521096 SubName: Full=2-isopropylma...   894   0.0  
tr|B2HKD3|B2HKD3_MYCMM Tax_Id=216594 (leuA)SubName: Full=2-isopr...   893   0.0  
sp|Q9CB76|LEU1_MYCLE Tax_Id=1769 (leuA)RecName: Full=2-isopropyl...   881   0.0  
tr|B8ZT16|B8ZT16_MYCLB Tax_Id=561304 (leuA)SubName: Full=2-isopr...   881   0.0  
tr|B1MFN6|B1MFN6_MYCA9 Tax_Id=561007 SubName: Full=Probable 2-is...   878   0.0  
sp|P96420|LEU1_MYCTU Tax_Id=1773 (leuA)RecName: Full=2-isopropyl...   857   0.0  
tr|C6DNF0|C6DNF0_MYCTK Tax_Id=478434 SubName: Full=2-isopropylma...   857   0.0  
tr|A5WTS8|A5WTS8_MYCTF Tax_Id=336982 SubName: Full=2-isopropylma...   857   0.0  
tr|A5U936|A5U936_MYCTA Tax_Id=419947 (leuA)SubName: Full=2-isopr...   857   0.0  
tr|D6G5I6|D6G5I6_MYCTU Tax_Id=478435 SubName: Full=2-isopropylma...   857   0.0  
tr|D5ZAT5|D5ZAT5_MYCTU Tax_Id=537209 SubName: Full=2-isopropylma...   857   0.0  
tr|D5YXY3|D5YXY3_MYCTU Tax_Id=515616 SubName: Full=2-isopropylma...   857   0.0  
tr|D5Y9W2|D5Y9W2_MYCTU Tax_Id=520141 SubName: Full=2-isopropylma...   857   0.0  
sp|Q7TVV6|LEU1_MYCBO Tax_Id=1765 (leuA)RecName: Full=2-isopropyl...   856   0.0  
tr|C1AIG4|C1AIG4_MYCBT Tax_Id=561275 (leuA)SubName: Full=2-isopr...   856   0.0  
tr|A1KQ42|A1KQ42_MYCBP Tax_Id=410289 (leuA)SubName: Full=2-isopr...   856   0.0  
tr|D6FTX5|D6FTX5_MYCTU Tax_Id=611304 SubName: Full=2-isopropylma...   856   0.0  
tr|D6FAR4|D6FAR4_MYCTU Tax_Id=611303 SubName: Full=2-isopropylma...   856   0.0  
tr|D6EZ63|D6EZ63_MYCTU Tax_Id=611302 SubName: Full=2-isopropylma...   856   0.0  
tr|D5ZMQ6|D5ZMQ6_MYCTU Tax_Id=537210 SubName: Full=2-isopropylma...   856   0.0  
tr|D5XNL4|D5XNL4_MYCTU Tax_Id=515617 SubName: Full=2-isopropylma...   854   0.0  
sp|A0PVE6|LEU1_MYCUA Tax_Id=362242 (leuA)RecName: Full=2-isoprop...   848   0.0  
tr|D5YLG0|D5YLG0_MYCTU Tax_Id=520140 SubName: Full=2-isopropylma...   822   0.0  
tr|C6WF52|C6WF52_ACTMD Tax_Id=446462 SubName: Full=2-isopropylma...   808   0.0  
tr|Q4JSM3|Q4JSM3_CORJK Tax_Id=306537 (leuA)SubName: Full=2-isopr...   806   0.0  
tr|C8RV49|C8RV49_CORJE Tax_Id=525262 (leuA)SubName: Full=2-isopr...   806   0.0  
tr|C5VA14|C5VA14_9CORY Tax_Id=553207 (leuA)SubName: Full=2-isopr...   794   0.0  
tr|B1VIR4|B1VIR4_CORU7 Tax_Id=504474 SubName: Full=2-isopropylma...   794   0.0  
tr|Q6NJX5|Q6NJX5_CORDI Tax_Id=1717 (leuA)SubName: Full=2-isoprop...   792   0.0  

>tr|A0R5Q2|A0R5Q2_MYCS2 Tax_Id=246196 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium smegmatis]
          Length = 602

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 544/586 (92%), Positives = 544/586 (92%)

Query: 1   MNTPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRT 60
           MNTPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRT
Sbjct: 1   MNTPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRT 60

Query: 61  WPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDF 120
           WPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 61  WPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDF 120

Query: 121 DFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFR 180
           DFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFR
Sbjct: 121 DFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFR 180

Query: 181 XXXXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGAT 240
                         ELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGAT
Sbjct: 181 ADKAAIKKIATDAAELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGAT 240

Query: 241 PDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQ 300
           PDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQ
Sbjct: 241 PDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQ 300

Query: 301 AGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 360
           AGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE
Sbjct: 301 AGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 360

Query: 361 RHPYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTY 420
           RHPYGGDLVYTAFSGSHQDAINKGLDQMKV           ILWQVPYLPIDPKDVGRTY
Sbjct: 361 RHPYGGDLVYTAFSGSHQDAINKGLDQMKVDADAAGADMDDILWQVPYLPIDPKDVGRTY 420

Query: 421 EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFS 480
           EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFS
Sbjct: 421 EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFS 480

Query: 481 EEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGAL 540
           EEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGAL
Sbjct: 481 EEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGAL 540

Query: 541 GINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           GINVNVRDYSEH                 IDGKTVWGVGIATSITT
Sbjct: 541 GINVNVRDYSEHAMSAGEEAQAAAYVEAEIDGKTVWGVGIATSITT 586


>tr|Q1B282|Q1B282_MYCSS Tax_Id=164756 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium sp.]
          Length = 601

 Score =  956 bits (2472), Expect = 0.0
 Identities = 472/586 (80%), Positives = 508/586 (86%), Gaps = 1/586 (0%)

Query: 1   MNTPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRT 60
           MNTP+ S+DAFS+ R IT PSG PHPGQPAWNTQR S+MPVSRYRSFA+EVE ++LPDRT
Sbjct: 1   MNTPE-STDAFSSVRAITTPSGPPHPGQPAWNTQRASAMPVSRYRSFAEEVEPVTLPDRT 59

Query: 61  WPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDF 120
           WPDKV++TAPMWCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 60  WPDKVVDTAPMWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 119

Query: 121 DFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFR 180
           DFVREIIE  AIPDDVTIQVLTQ RPELITRTFEAC+GA   IVHFYNSTSILQRRVVFR
Sbjct: 120 DFVREIIEQGAIPDDVTIQVLTQCRPELITRTFEACKGAPRAIVHFYNSTSILQRRVVFR 179

Query: 181 XXXXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGAT 240
                          + +EEA K+PDT WR+EYSPESYTGTEL YA +VC+AV +I+  T
Sbjct: 180 ADREAVKQIAVDGARMCVEEAAKHPDTLWRFEYSPESYTGTELEYAVDVCNAVADIVKPT 239

Query: 241 PDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQ 300
           P+ P+I+NLPATVEMATPNVYADSIEWM+R+L+ RDS+ILSLHPHNDRGT VAAAELGYQ
Sbjct: 240 PEVPLIVNLPATVEMATPNVYADSIEWMNRHLSPRDSIILSLHPHNDRGTAVAAAELGYQ 299

Query: 301 AGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 360
           AGADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE
Sbjct: 300 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 359

Query: 361 RHPYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTY 420
           RHPYGGDLVYTAFSGSHQDAINKGLD MKV           ILWQVPYLPIDPKDVGRTY
Sbjct: 360 RHPYGGDLVYTAFSGSHQDAINKGLDAMKVAADEADSDVDDILWQVPYLPIDPKDVGRTY 419

Query: 421 EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFS 480
           EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQ IQ+ITDGEGGEVSPKEMWD F+
Sbjct: 420 EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAIQKITDGEGGEVSPKEMWDVFA 479

Query: 481 EEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGAL 540
           EEYL+P+ PLERMRQKVDAAE DGGTD ITAVVKV+G EREIVGAGNGPLAAFCDALGA+
Sbjct: 480 EEYLSPVRPLERMRQKVDAAEVDGGTDTITAVVKVDGVEREIVGAGNGPLAAFCDALGAI 539

Query: 541 GINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           G +++V DYSEH                 + GKTVWGVGIATSITT
Sbjct: 540 GFDISVLDYSEHALSAGEEAQAAAYVEASVGGKTVWGVGIATSITT 585


>tr|A3Q7A2|A3Q7A2_MYCSJ Tax_Id=164757 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium sp.]
          Length = 601

 Score =  956 bits (2472), Expect = 0.0
 Identities = 472/586 (80%), Positives = 508/586 (86%), Gaps = 1/586 (0%)

Query: 1   MNTPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRT 60
           MNTP+ S+DAFS+ R IT PSG PHPGQPAWNTQR S+MPVSRYRSFA+EVE ++LPDRT
Sbjct: 1   MNTPE-STDAFSSVRAITTPSGPPHPGQPAWNTQRASAMPVSRYRSFAEEVEPVTLPDRT 59

Query: 61  WPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDF 120
           WPDKV++TAPMWCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 60  WPDKVVDTAPMWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 119

Query: 121 DFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFR 180
           DFVREIIE  AIPDDVTIQVLTQ RPELITRTFEAC+GA   IVHFYNSTSILQRRVVFR
Sbjct: 120 DFVREIIEQGAIPDDVTIQVLTQCRPELITRTFEACKGAPRAIVHFYNSTSILQRRVVFR 179

Query: 181 XXXXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGAT 240
                          + +EEA K+PDT WR+EYSPESYTGTEL YA +VC+AV +I+  T
Sbjct: 180 ADREAVKQIAVDGARMCVEEAAKHPDTLWRFEYSPESYTGTELEYAVDVCNAVADIVKPT 239

Query: 241 PDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQ 300
           P+ P+I+NLPATVEMATPNVYADSIEWM+R+L+ RDS+ILSLHPHNDRGT VAAAELGYQ
Sbjct: 240 PEVPLIVNLPATVEMATPNVYADSIEWMNRHLSPRDSIILSLHPHNDRGTAVAAAELGYQ 299

Query: 301 AGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 360
           AGADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE
Sbjct: 300 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 359

Query: 361 RHPYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTY 420
           RHPYGGDLVYTAFSGSHQDAINKGLD MKV           ILWQVPYLPIDPKDVGRTY
Sbjct: 360 RHPYGGDLVYTAFSGSHQDAINKGLDAMKVAADEADSDVDDILWQVPYLPIDPKDVGRTY 419

Query: 421 EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFS 480
           EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQ IQ+ITDGEGGEVSPKEMWD F+
Sbjct: 420 EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAIQKITDGEGGEVSPKEMWDVFA 479

Query: 481 EEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGAL 540
           EEYL+P+ PLERMRQKVDAAE DGGTD ITAVVKV+G EREIVGAGNGPLAAFCDALGA+
Sbjct: 480 EEYLSPVRPLERMRQKVDAAEVDGGTDTITAVVKVDGVEREIVGAGNGPLAAFCDALGAI 539

Query: 541 GINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           G +++V DYSEH                 + GKTVWGVGIATSITT
Sbjct: 540 GFDISVLDYSEHALSAGEEAQAAAYVEASVGGKTVWGVGIATSITT 585


>tr|A1UMW8|A1UMW8_MYCSK Tax_Id=189918 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium sp.]
          Length = 601

 Score =  956 bits (2472), Expect = 0.0
 Identities = 472/586 (80%), Positives = 508/586 (86%), Gaps = 1/586 (0%)

Query: 1   MNTPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRT 60
           MNTP+ S+DAFS+ R IT PSG PHPGQPAWNTQR S+MPVSRYRSFA+EVE ++LPDRT
Sbjct: 1   MNTPE-STDAFSSVRAITTPSGPPHPGQPAWNTQRASAMPVSRYRSFAEEVEPVTLPDRT 59

Query: 61  WPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDF 120
           WPDKV++TAPMWCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDF
Sbjct: 60  WPDKVVDTAPMWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDF 119

Query: 121 DFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFR 180
           DFVREIIE  AIPDDVTIQVLTQ RPELITRTFEAC+GA   IVHFYNSTSILQRRVVFR
Sbjct: 120 DFVREIIEQGAIPDDVTIQVLTQCRPELITRTFEACKGAPRAIVHFYNSTSILQRRVVFR 179

Query: 181 XXXXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGAT 240
                          + +EEA K+PDT WR+EYSPESYTGTEL YA +VC+AV +I+  T
Sbjct: 180 ADREAVKQIAVDGARMCVEEAAKHPDTLWRFEYSPESYTGTELEYAVDVCNAVADIVKPT 239

Query: 241 PDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQ 300
           P+ P+I+NLPATVEMATPNVYADSIEWM+R+L+ RDS+ILSLHPHNDRGT VAAAELGYQ
Sbjct: 240 PEVPLIVNLPATVEMATPNVYADSIEWMNRHLSPRDSIILSLHPHNDRGTAVAAAELGYQ 299

Query: 301 AGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 360
           AGADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE
Sbjct: 300 AGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHE 359

Query: 361 RHPYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTY 420
           RHPYGGDLVYTAFSGSHQDAINKGLD MKV           ILWQVPYLPIDPKDVGRTY
Sbjct: 360 RHPYGGDLVYTAFSGSHQDAINKGLDAMKVAADEADSDVDDILWQVPYLPIDPKDVGRTY 419

Query: 421 EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFS 480
           EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQ IQ+ITDGEGGEVSPKEMWD F+
Sbjct: 420 EAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAIQKITDGEGGEVSPKEMWDVFA 479

Query: 481 EEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGAL 540
           EEYL+P+ PLERMRQKVDAAE DGGTD ITAVVKV+G EREIVGAGNGPLAAFCDALGA+
Sbjct: 480 EEYLSPVRPLERMRQKVDAAEVDGGTDTITAVVKVDGVEREIVGAGNGPLAAFCDALGAI 539

Query: 541 GINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           G +++V DYSEH                 + GKTVWGVGIATSITT
Sbjct: 540 GFDISVLDYSEHALSAGEEAQAAAYVEASVGGKTVWGVGIATSITT 585


>tr|C3JNY6|C3JNY6_RHOER Tax_Id=596309 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus erythropolis SK121]
          Length = 602

 Score =  946 bits (2446), Expect = 0.0
 Identities = 472/585 (80%), Positives = 497/585 (84%), Gaps = 6/585 (1%)

Query: 8   SDAFSTG-RTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVI 66
           +DAF+TG RTITPP+      QPAWNTQ+ SSMP  RYR FA+EVE ++LPDRTWPDK+I
Sbjct: 4   ADAFTTGTRTITPPTKPAPSDQPAWNTQKNSSMPTFRYRPFAEEVETVTLPDRTWPDKII 63

Query: 67  ETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 126
           + AP WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI
Sbjct: 64  DRAPQWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 123

Query: 127 IEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXX 186
           IED AIP DVTIQVLTQSRPELI RTFEAC GA+N IVHFYNSTSILQRRVVFR      
Sbjct: 124 IEDGAIPSDVTIQVLTQSRPELIKRTFEACEGAENAIVHFYNSTSILQRRVVFRADKDTI 183

Query: 187 XXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVI 246
                   ELVL E+KKYPDTNWRWEYSPESYTGTEL YAKEVCDAVTE LGATP NPVI
Sbjct: 184 KKIATDAAELVLAESKKYPDTNWRWEYSPESYTGTELEYAKEVCDAVTETLGATPANPVI 243

Query: 247 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 306
           LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI
Sbjct: 244 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 303

Query: 307 EGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 366
           EGCLFGNGERTGNVCLVTL LNMF+RGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG
Sbjct: 304 EGCLFGNGERTGNVCLVTLALNMFTRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 363

Query: 367 DLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRV 426
           DLVYTAFSGSHQDAINKGLD MKV           ILWQVPYLPIDPKDVGR+YEAVIRV
Sbjct: 364 DLVYTAFSGSHQDAINKGLDAMKVDADSQNSDVDDILWQVPYLPIDPKDVGRSYEAVIRV 423

Query: 427 NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAP 486
           NSQSGKGGVAYIMKADHGLVLPRRLQ+EFSQ +Q+ITDGEGGEVSPKEMWD F EEYLAP
Sbjct: 424 NSQSGKGGVAYIMKADHGLVLPRRLQVEFSQSVQKITDGEGGEVSPKEMWDVFHEEYLAP 483

Query: 487 ITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNV 546
           ITPLERM+QKV A+EEDGGTD ITA+VKVNG+E+EI G GNGPLAAF DALG++  +V V
Sbjct: 484 ITPLERMKQKVTASEEDGGTDAITAIVKVNGKEQEISGTGNGPLAAFVDALGSINFDVRV 543

Query: 547 RDYSEHXXXXXXXXXXXXXXXXXIDG-----KTVWGVGIATSITT 586
            DYSEH                 + G       VWGVGIATSITT
Sbjct: 544 LDYSEHAMSAGDDAQAAAYVECAVTGPEGQSTVVWGVGIATSITT 588


>tr|C0ZN67|C0ZN67_RHOE4 Tax_Id=234621 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus erythropolis]
          Length = 602

 Score =  946 bits (2445), Expect = 0.0
 Identities = 471/585 (80%), Positives = 497/585 (84%), Gaps = 6/585 (1%)

Query: 8   SDAFSTG-RTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVI 66
           +DAF+TG RTITPP+      QPAWNTQ+ SSMP  RYR FA+EVE ++LPDRTWPDK+I
Sbjct: 4   ADAFTTGTRTITPPTKPAPSDQPAWNTQKNSSMPTFRYRPFAEEVETVTLPDRTWPDKII 63

Query: 67  ETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 126
           + AP WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI
Sbjct: 64  DRAPQWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 123

Query: 127 IEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXX 186
           IED AIP DVTIQVLTQSRPELI RTFEAC GA+N IVHFYNSTSILQRRVVFR      
Sbjct: 124 IEDGAIPSDVTIQVLTQSRPELIKRTFEACEGAENAIVHFYNSTSILQRRVVFRADKDTI 183

Query: 187 XXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVI 246
                   ELVL E+KKYPDTNWRWEYSPESYTGTEL YAKEVCDAVTE LGATP NPVI
Sbjct: 184 KKIATDAAELVLAESKKYPDTNWRWEYSPESYTGTELEYAKEVCDAVTETLGATPANPVI 243

Query: 247 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 306
           LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI
Sbjct: 244 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 303

Query: 307 EGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 366
           EGCLFGNGERTGNVCLVTL LNMF+RGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG
Sbjct: 304 EGCLFGNGERTGNVCLVTLALNMFTRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 363

Query: 367 DLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRV 426
           DLVYTAFSGSHQDAINKGLD MKV           ILWQVPYLPIDPKDVGR+YEAVIRV
Sbjct: 364 DLVYTAFSGSHQDAINKGLDAMKVDADNQDSDVDDILWQVPYLPIDPKDVGRSYEAVIRV 423

Query: 427 NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAP 486
           NSQSGKGGVAYIMKADHGLVLPRRLQ+EFSQ +Q+ITDGEGGEVSPKEMWD F EEYLAP
Sbjct: 424 NSQSGKGGVAYIMKADHGLVLPRRLQVEFSQSVQKITDGEGGEVSPKEMWDVFHEEYLAP 483

Query: 487 ITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNV 546
           +TPLERM+QKV A+EEDGGTD ITA+VKVNG+E+EI G GNGPLAAF DALG++  +V V
Sbjct: 484 VTPLERMKQKVTASEEDGGTDAITAIVKVNGKEQEISGTGNGPLAAFVDALGSINFDVRV 543

Query: 547 RDYSEHXXXXXXXXXXXXXXXXXIDG-----KTVWGVGIATSITT 586
            DYSEH                 + G       VWGVGIATSITT
Sbjct: 544 LDYSEHAMSAGDDAQAAAYVECAVTGPDGQSTVVWGVGIATSITT 588


>tr|C1B9P5|C1B9P5_RHOOB Tax_Id=632772 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus opacus]
          Length = 602

 Score =  936 bits (2420), Expect = 0.0
 Identities = 469/585 (80%), Positives = 492/585 (84%), Gaps = 6/585 (1%)

Query: 8   SDAFSTG-RTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVI 66
           +DAF++G RTITPPS      QP WNTQ+ SSMP  RYRSF++EVE +SLPDRTWPDK+I
Sbjct: 4   ADAFTSGTRTITPPSKPAPSDQPIWNTQKNSSMPTFRYRSFSEEVEPVSLPDRTWPDKII 63

Query: 67  ETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 126
           + AP WCAVDLRDGNQALIDPMSP RKRRMF+LLVRMGYKEIEVGFPSASQTDFDFVREI
Sbjct: 64  DRAPQWCAVDLRDGNQALIDPMSPARKRRMFELLVRMGYKEIEVGFPSASQTDFDFVREI 123

Query: 127 IEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXX 186
           IED AIPDDVTIQVLTQSRPELI RTFEAC GA  VIVHFYNSTS+LQRRVVF+      
Sbjct: 124 IEDGAIPDDVTIQVLTQSRPELIKRTFEACEGANKVIVHFYNSTSVLQRRVVFKADREVI 183

Query: 187 XXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVI 246
                    L LEEAKKYPDT WRWEYSPESYTGTEL YAKEVCDAVTE+L  TP NPVI
Sbjct: 184 KKIATDAATLALEEAKKYPDTQWRWEYSPESYTGTELEYAKEVCDAVTEVLQPTPQNPVI 243

Query: 247 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 306
           LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI
Sbjct: 244 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 303

Query: 307 EGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 366
           EGCLFGNGERTGNVCLVTLGLNMF+RGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG
Sbjct: 304 EGCLFGNGERTGNVCLVTLGLNMFTRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 363

Query: 367 DLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRV 426
           DLVYTAFSGSHQDAINKGLD MK            ILW VPYLPIDPKDVGRTYEAVIRV
Sbjct: 364 DLVYTAFSGSHQDAINKGLDAMKFDADSQDADVDDILWAVPYLPIDPKDVGRTYEAVIRV 423

Query: 427 NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAP 486
           NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQ +Q+ITDGEGGEVSPKEMWD F EEYLAP
Sbjct: 424 NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAVQRITDGEGGEVSPKEMWDVFHEEYLAP 483

Query: 487 ITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNV 546
           ITPLERM+QKV AAEEDGGTD ITA VKVNG+E EI G+GNGPLAAF DAL  +  +V V
Sbjct: 484 ITPLERMKQKVTAAEEDGGTDSITATVKVNGKEHEISGSGNGPLAAFVDALATIDFDVRV 543

Query: 547 RDYSEHXXXXXXXXXXXXXXXXXI---DGK--TVWGVGIATSITT 586
            DYSEH                 +   DG+   VWGVGIATSITT
Sbjct: 544 LDYSEHAMSAGDDAQAAAYVECAVTAPDGRNTVVWGVGIATSITT 588


>tr|A4T617|A4T617_MYCGI Tax_Id=350054 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium gilvum]
          Length = 606

 Score =  936 bits (2420), Expect = 0.0
 Identities = 466/580 (80%), Positives = 494/580 (85%)

Query: 7   SSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVI 66
           S+DAFS+ RTI  P+G P+PGQP+WNTQR SSMPV+RYRSF DEVE I LPDRTWP+K I
Sbjct: 8   SADAFSSVRTIVTPAGKPNPGQPSWNTQRASSMPVNRYRSFDDEVEPIRLPDRTWPEKAI 67

Query: 67  ETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 126
            TAPMW AVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI
Sbjct: 68  TTAPMWAAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 127

Query: 127 IEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXX 186
           IE  AIPDDVTIQVLTQ RPELI RTF AC+GA   IVHFYNSTSILQRRVVFR      
Sbjct: 128 IEQGAIPDDVTIQVLTQCRPELIERTFLACQGAPRAIVHFYNSTSILQRRVVFRADRDAV 187

Query: 187 XXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVI 246
                    + +EEAKKYP T WR+EYSPESYTGTEL YA EVC+AV E++  TP+ P+I
Sbjct: 188 KQIATDGARMCVEEAKKYPGTQWRYEYSPESYTGTELEYAVEVCNAVAEVVQPTPEWPLI 247

Query: 247 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 306
           +NLPATVEMATPNVYADSIEWMHR+L  RDS+ILSLHPHNDRGT VAAAELGY AGADRI
Sbjct: 248 VNLPATVEMATPNVYADSIEWMHRHLTPRDSIILSLHPHNDRGTAVAAAELGYAAGADRI 307

Query: 307 EGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 366
           EGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQL V ERHPYGG
Sbjct: 308 EGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLAVPERHPYGG 367

Query: 367 DLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRV 426
           DLVYTAFSGSHQDAINKGLD MK            +LWQVPYLPIDPKDVGRTYEAVIRV
Sbjct: 368 DLVYTAFSGSHQDAINKGLDAMKFDADAADKDVDDLLWQVPYLPIDPKDVGRTYEAVIRV 427

Query: 427 NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAP 486
           NSQSGKGGVAYIMKADHGL LPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAF EEYLAP
Sbjct: 428 NSQSGKGGVAYIMKADHGLALPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFYEEYLAP 487

Query: 487 ITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNV 546
           +TPLER+RQKVDAAE DGGTD ITAVVK++GEEREIVGAGNGPLAAF DA+GA+G NVNV
Sbjct: 488 VTPLERIRQKVDAAEVDGGTDTITAVVKIDGEEREIVGAGNGPLAAFVDAVGAVGFNVNV 547

Query: 547 RDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
            DYSEH                 IDG+TVWGVGIATSITT
Sbjct: 548 LDYSEHAMSAGEEAQAAAYVEAEIDGRTVWGVGIATSITT 587


>tr|Q0S8X0|Q0S8X0_RHOSR Tax_Id=101510 (leuA1)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus sp.]
          Length = 602

 Score =  932 bits (2408), Expect = 0.0
 Identities = 467/585 (79%), Positives = 493/585 (84%), Gaps = 6/585 (1%)

Query: 8   SDAFSTG-RTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVI 66
           +DAF++G RTITPPS      QP WNTQ+ SSMP  RYRSF++EVE +SLPDR+WPDKVI
Sbjct: 4   ADAFTSGTRTITPPSKPAPSDQPEWNTQKNSSMPTFRYRSFSEEVEPVSLPDRSWPDKVI 63

Query: 67  ETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 126
           + AP WCAVDLRDGNQALIDPMSP RKRRMF+LLVRMGYKEIEVGFPSASQTDFDFVREI
Sbjct: 64  DRAPQWCAVDLRDGNQALIDPMSPARKRRMFELLVRMGYKEIEVGFPSASQTDFDFVREI 123

Query: 127 IEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXX 186
           IED AIPDDVTIQVLTQSRPELI RTFEAC GA  VIVHFYNSTSILQRRVVF+      
Sbjct: 124 IEDGAIPDDVTIQVLTQSRPELIKRTFEACEGANKVIVHFYNSTSILQRRVVFKAERDVI 183

Query: 187 XXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVI 246
                    L LEEAK+YPDT WRWEYSPESYTGTEL YAKEVCDAVTE+L  TP+NPVI
Sbjct: 184 KKIATDAATLALEEAKQYPDTQWRWEYSPESYTGTELEYAKEVCDAVTEVLQPTPENPVI 243

Query: 247 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 306
           LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI
Sbjct: 244 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 303

Query: 307 EGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 366
           EGCLFGNGERTGNVCLVTLGLNMF+RGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG
Sbjct: 304 EGCLFGNGERTGNVCLVTLGLNMFTRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 363

Query: 367 DLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRV 426
           DLVYTAFSGSHQDAINKGLD MK            ILW VPYLPIDPKDVGRTYEAVIRV
Sbjct: 364 DLVYTAFSGSHQDAINKGLDAMKFDADSQDADVDDILWAVPYLPIDPKDVGRTYEAVIRV 423

Query: 427 NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAP 486
           NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQ +Q+ITDGEGGEVSPKEMWD F EEYLAP
Sbjct: 424 NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAVQRITDGEGGEVSPKEMWDVFHEEYLAP 483

Query: 487 ITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNV 546
           ITPLERM+QKV A+EEDGGTD ITA VKV+G+E EI G+GNGPLAAF DAL  +  +V V
Sbjct: 484 ITPLERMKQKVTASEEDGGTDSITATVKVDGKEHEISGSGNGPLAAFVDALATIDFDVRV 543

Query: 547 RDYSEHXXXXXXXXXXXXXXXXXI---DGK--TVWGVGIATSITT 586
            DYSEH                 +   DG+   VWGVGIATSITT
Sbjct: 544 LDYSEHAMSAGDDAQAAAYVECAVTAPDGRNTVVWGVGIATSITT 588


>tr|A1TGI1|A1TGI1_MYCVP Tax_Id=350058 SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           vanbaalenii]
          Length = 612

 Score =  927 bits (2396), Expect = 0.0
 Identities = 465/583 (79%), Positives = 496/583 (85%), Gaps = 3/583 (0%)

Query: 7   SSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVE---KISLPDRTWPD 63
           S+DA+S+ RTIT P+G P+PGQP+WNTQRGSSMPVSRYR+FA EV      +  DRTWPD
Sbjct: 8   SADAYSSVRTITTPAGPPNPGQPSWNTQRGSSMPVSRYRNFAAEVPGGAPAAPFDRTWPD 67

Query: 64  KVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFV 123
           KVI+TAP+WCAVDLRDGNQALIDPMSP RKRRMFDLLV+MGYKEIEVGFPSASQTD+DFV
Sbjct: 68  KVIDTAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVKMGYKEIEVGFPSASQTDYDFV 127

Query: 124 REIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXX 183
           REIIE  AIPDDVTIQVLTQ R ELI RTFEAC GA NVIVHFYNSTSILQRRVVFR   
Sbjct: 128 REIIEQGAIPDDVTIQVLTQCRDELIERTFEACDGAPNVIVHFYNSTSILQRRVVFRADR 187

Query: 184 XXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDN 243
                         LEEA K+P T WR+EYSPESYTGTEL YA +VC+AV+E++  TPD 
Sbjct: 188 DEIKKIATDGARKCLEEAGKHPGTRWRYEYSPESYTGTELEYALDVCNAVSEVIEPTPDW 247

Query: 244 PVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGA 303
           P+I+NLPATVEMATPNVYADSIEWM RNLARR S+ILSLHPHNDRGT VAAAELGYQAGA
Sbjct: 248 PLIVNLPATVEMATPNVYADSIEWMSRNLARRGSIILSLHPHNDRGTAVAAAELGYQAGA 307

Query: 304 DRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHP 363
           DRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQL VHERHP
Sbjct: 308 DRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLGVHERHP 367

Query: 364 YGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAV 423
           YGGDLVYTAFSGSHQDAINKGLD MK+           I+WQVPYLPIDPKDVGRTYEAV
Sbjct: 368 YGGDLVYTAFSGSHQDAINKGLDAMKISADEQDSDVDDIVWQVPYLPIDPKDVGRTYEAV 427

Query: 424 IRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEY 483
           IRVNSQSGKGGVAYIMKADHGL LPRRLQIEFSQ IQQITDGEGGEVSPKEMWDAF +EY
Sbjct: 428 IRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSQAIQQITDGEGGEVSPKEMWDAFYDEY 487

Query: 484 LAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGIN 543
           LAPITPLER+RQKVDA+E DGGTD ITAVVKVNGEE EIVGAGNGPLAAF DA+GA+G +
Sbjct: 488 LAPITPLERIRQKVDASEVDGGTDTITAVVKVNGEEHEIVGAGNGPLAAFVDAIGAVGFH 547

Query: 544 VNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           VNV DYSEH                 IDGKTVWGVGIATSITT
Sbjct: 548 VNVLDYSEHAMSAGEEAAAAAYVEAEIDGKTVWGVGIATSITT 590


>tr|D5PKD7|D5PKD7_COREQ Tax_Id=525370 (leuA2)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Rhodococcus equi ATCC 33707]
          Length = 567

 Score =  911 bits (2355), Expect = 0.0
 Identities = 455/553 (82%), Positives = 478/553 (86%), Gaps = 5/553 (0%)

Query: 39  MPVSRYRSFADEVEKISLPDRTWPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFD 98
           MP  RYR F +EVE +SLPDRTWPDKVI+ AP WCAVDLRDGNQALIDPMSP RKRRMF+
Sbjct: 1   MPTFRYRPFGEEVETVSLPDRTWPDKVIDRAPQWCAVDLRDGNQALIDPMSPARKRRMFE 60

Query: 99  LLVRMGYKEIEVGFPSASQTDFDFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRG 158
           LLVRMGYKEIEVGFPSASQTDFDFVREIIEDNAIPDDVTIQVLTQSRPELI RTFEAC G
Sbjct: 61  LLVRMGYKEIEVGFPSASQTDFDFVREIIEDNAIPDDVTIQVLTQSRPELIKRTFEACDG 120

Query: 159 AKNVIVHFYNSTSILQRRVVFRXXXXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESY 218
           AKNVIVHFYNSTSILQRRVVFR               LVLEEAK +PDTNWRWEYSPESY
Sbjct: 121 AKNVIVHFYNSTSILQRRVVFRADKDAIKKIATDAAALVLEEAKNHPDTNWRWEYSPESY 180

Query: 219 TGTELSYAKEVCDAVTEILGATPDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSV 278
           TGTELSYAKEVCDAV E LGATPDN VI+NLPATVEMATPNVYADSIEWMHRNLA+R+S+
Sbjct: 181 TGTELSYAKEVCDAVVETLGATPDNRVIINLPATVEMATPNVYADSIEWMHRNLAQRESI 240

Query: 279 ILSLHPHNDRGTGVAAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQI 338
           ILSLHPHNDRGTGVAAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNMF+RGVDPQI
Sbjct: 241 ILSLHPHNDRGTGVAAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNMFTRGVDPQI 300

Query: 339 DFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXX 398
           DFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLD MKV        
Sbjct: 301 DFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKVAADQQDAD 360

Query: 399 XXXILWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQV 458
              I+W+VPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQ 
Sbjct: 361 VDDIVWEVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQA 420

Query: 459 IQQITDGEGGEVSPKEMWDAFSEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGE 518
           +Q+ITDGEGGEVSPKE+WD F+EEYL+P++PLERMRQKV AAEEDGGTD ITAVVKVNG 
Sbjct: 421 VQKITDGEGGEVSPKEIWDVFAEEYLSPVSPLERMRQKVTAAEEDGGTDAITAVVKVNGV 480

Query: 519 EREIVGAGNGPLAAFCDALGALGINVNVRDYSEHXXXXXXXXXXXXXXXXXI---DG--K 573
           E+EI GAGNGPLAAF DALG +G +V V DYSEH                 +   DG  K
Sbjct: 481 EQEISGAGNGPLAAFVDALGTVGFDVRVLDYSEHAMSAGDDAQAAAYVECAVTLPDGTSK 540

Query: 574 TVWGVGIATSITT 586
            VWGVGIATSITT
Sbjct: 541 VVWGVGIATSITT 553


>tr|A0Q9T9|A0Q9T9_MYCA1 Tax_Id=243243 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium avium]
          Length = 599

 Score =  910 bits (2353), Expect = 0.0
 Identities = 447/578 (77%), Positives = 485/578 (83%)

Query: 9   DAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVIET 68
           DAFS+ R+I  P+G P PGQPAWN QRGSSMPV+RYR FA+EVE I LPDRTWPDKVI+ 
Sbjct: 6   DAFSSSRSIVKPAGPPGPGQPAWNPQRGSSMPVNRYRPFAEEVEPIRLPDRTWPDKVIDR 65

Query: 69  APMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIE 128
           AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI+ 
Sbjct: 66  APLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIVT 125

Query: 129 DNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXXXX 188
           + AIPDDVTIQVLTQ RPELI RTF AC+GA   IVHFYNSTSILQRRVVFR        
Sbjct: 126 EGAIPDDVTIQVLTQCRPELIERTFAACQGAPQAIVHFYNSTSILQRRVVFRADRAAVQE 185

Query: 189 XXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVILN 248
                    +EEA KYP+T WR+EYSPESYTGTEL YAK+VCDAV EI+  TP+NP+I N
Sbjct: 186 IAVAGARKCVEEAAKYPETRWRFEYSPESYTGTELEYAKQVCDAVGEIIRPTPENPIIFN 245

Query: 249 LPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRIEG 308
           LPATVEMATPNVYADSIEWM RNLARRDSVILSLHPHNDRGT VAAAELGY AGADRIEG
Sbjct: 246 LPATVEMATPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGYAAGADRIEG 305

Query: 309 CLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL 368
           CLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL
Sbjct: 306 CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL 365

Query: 369 VYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRVNS 428
           VYTAFSGSHQDAINKGLDQM++           +LWQVPYLPIDPKDVGRTYEAVIRVNS
Sbjct: 366 VYTAFSGSHQDAINKGLDQMEIDADAADTDVEDMLWQVPYLPIDPKDVGRTYEAVIRVNS 425

Query: 429 QSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAPIT 488
           QSGKGGVAYIMKADHGL LPRRLQIEFSQVIQ+I++GEGGEVSPKEMWDAF EEYLAP+ 
Sbjct: 426 QSGKGGVAYIMKADHGLALPRRLQIEFSQVIQKISEGEGGEVSPKEMWDAFFEEYLAPVW 485

Query: 489 PLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNVRD 548
           PLER++Q+VDA++ED G   I+A VK+NGE+ EI G GNGPLAAF  AL  +G +V V D
Sbjct: 486 PLERVKQRVDASDEDSGVTSISATVKINGEQTEINGTGNGPLAAFVHALAGVGFDVAVLD 545

Query: 549 YSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           YSEH                 ++G+TVWGVGIA SITT
Sbjct: 546 YSEHAMSSGDDAQAAAYVEASVNGRTVWGVGIAPSITT 583


>tr|Q744M9|Q744M9_MYCPA Tax_Id=1770 (leuA)SubName:
           Full=LeuA;[Mycobacterium paratuberculosis]
          Length = 614

 Score =  909 bits (2350), Expect = 0.0
 Identities = 448/578 (77%), Positives = 484/578 (83%)

Query: 9   DAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVIET 68
           DAFS+ R+I  P+G P PGQPAWN QRGSSMPV+RYR FA+EVE I LPDRTWPDKVI+ 
Sbjct: 21  DAFSSSRSIVKPAGPPGPGQPAWNPQRGSSMPVNRYRPFAEEVEPIRLPDRTWPDKVIDR 80

Query: 69  APMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIE 128
           AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 
Sbjct: 81  APLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIT 140

Query: 129 DNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXXXX 188
           + AIPDDVTIQVLTQ RPELI RTF AC+GA   IVHFYNSTSILQRRVVFR        
Sbjct: 141 EGAIPDDVTIQVLTQCRPELIERTFAACQGAPQAIVHFYNSTSILQRRVVFRADRAAVQE 200

Query: 189 XXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVILN 248
                    +EEA KYP+T WR+EYSPESYTGTEL YAK+VCDAV EI+  T +NP+I N
Sbjct: 201 IAVAGARKCVEEAAKYPETQWRFEYSPESYTGTELEYAKQVCDAVGEIIRPTTENPIIFN 260

Query: 249 LPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRIEG 308
           LPATVEMATPNVYADSIEWM RNLARRDSVILSLHPHNDRGT VAAAELGY AGADRIEG
Sbjct: 261 LPATVEMATPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGYAAGADRIEG 320

Query: 309 CLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL 368
           CLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL
Sbjct: 321 CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL 380

Query: 369 VYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRVNS 428
           VYTAFSGSHQDAINKGLDQMK+           +LWQVPYLPIDPKDVGRTYEAVIRVNS
Sbjct: 381 VYTAFSGSHQDAINKGLDQMKIDADAADTDVEDMLWQVPYLPIDPKDVGRTYEAVIRVNS 440

Query: 429 QSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAPIT 488
           QSGKGGVAYIMKADHGL LPRRLQIEFSQVIQ+I++GEGGEVSPKEMWDAF EEYLAP+ 
Sbjct: 441 QSGKGGVAYIMKADHGLALPRRLQIEFSQVIQKISEGEGGEVSPKEMWDAFFEEYLAPVW 500

Query: 489 PLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNVRD 548
           PLER++Q+VDA++ED G   I+A VK+NGE+ EI G GNGPLAAF  AL  +G +V V D
Sbjct: 501 PLERVKQRVDASDEDSGVTSISATVKINGEQTEINGTGNGPLAAFVHALAGVGFDVAVLD 560

Query: 549 YSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           YSEH                 ++G+TVWGVGIA SITT
Sbjct: 561 YSEHAMSSGDDAQAAAYVEASVNGRTVWGVGIAPSITT 598


>tr|D0LDG8|D0LDG8_GORB4 Tax_Id=526226 SubName:
           Full=2-isopropylmalate synthase;[Gordonia bronchialis]
          Length = 617

 Score =  907 bits (2345), Expect = 0.0
 Identities = 451/581 (77%), Positives = 485/581 (83%), Gaps = 1/581 (0%)

Query: 7   SSDAFSTGRT-ITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKV 65
           ++D F++G + I  PSG    GQPAWNTQRGS+MP+ RYR FADEVE IS+PDRTWPDKV
Sbjct: 3   AADTFTSGASRIVEPSGPIPAGQPAWNTQRGSAMPIHRYRQFADEVETISIPDRTWPDKV 62

Query: 66  IETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 125
           I  APMW AVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTD+DFVRE
Sbjct: 63  ITKAPMWGAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDYDFVRE 122

Query: 126 IIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXX 185
           IIED AIPDDVTIQVLTQ R ELI RTF+ACRGA  VIVHFYNSTS+LQRRVVFR     
Sbjct: 123 IIEDGAIPDDVTIQVLTQCRDELIERTFDACRGANKVIVHFYNSTSVLQRRVVFRADKDA 182

Query: 186 XXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPV 245
                      VL E  KYPDT WR+EYSPESYTGTELSYAK VCDAVTEI+  TPDNP+
Sbjct: 183 ITKIATDAAHKVLVEQAKYPDTQWRYEYSPESYTGTELSYAKHVCDAVTEIIAPTPDNPM 242

Query: 246 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 305
           I+NLPATVEMATPNVYADSIEWMHRNL RRDS+ILSLHPHNDRGT VAAAELGYQAGADR
Sbjct: 243 IINLPATVEMATPNVYADSIEWMHRNLERRDSIILSLHPHNDRGTAVAAAELGYQAGADR 302

Query: 306 IEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 365
           IEGCLFGNGERTGNVCLVTLG+N+FSRGVDPQI FS+IDEIRRTVEYCNQL V ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLGMNLFSRGVDPQISFSDIDEIRRTVEYCNQLNVPERHPYG 362

Query: 366 GDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIR 425
           GDLVYTAFSGSHQDAINKGLDQMK            ILWQVPYLPIDPKDVGR YEAVIR
Sbjct: 363 GDLVYTAFSGSHQDAINKGLDQMKYDADASDRDVDDILWQVPYLPIDPKDVGRNYEAVIR 422

Query: 426 VNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLA 485
           VNSQSGKGGVAYIMKADHG+ LPRRLQIEFS+ IQ+ITDGEGGEV+PKEMWD F+E YLA
Sbjct: 423 VNSQSGKGGVAYIMKADHGMNLPRRLQIEFSREIQKITDGEGGEVNPKEMWDVFAENYLA 482

Query: 486 PITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVN 545
           PI PLERMRQKVDAAE DGG D+ITA+VKV G EREI G+GNGPLAAF DAL  +G +V 
Sbjct: 483 PIWPLERMRQKVDAAEVDGGEDRITAIVKVEGNEREIAGSGNGPLAAFVDALSTVGYDVR 542

Query: 546 VRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           V DYSEH                 ++G+TVWGVG+A+SITT
Sbjct: 543 VLDYSEHALTSGGDASAAAYVEAEVNGETVWGVGVASSITT 583


>tr|Q5Z341|Q5Z341_NOCFA Tax_Id=37329 (leuA)SubName: Full=Putative
           2-isopropylmalate synthase;[Nocardia farcinica]
          Length = 597

 Score =  906 bits (2341), Expect = 0.0
 Identities = 449/580 (77%), Positives = 484/580 (83%), Gaps = 1/580 (0%)

Query: 8   SDAFSTG-RTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVI 66
           +DA+ +G R IT PS      QPAWN Q+ SSMP  RYR FA+EVE ++LPDRTWPDKVI
Sbjct: 4   ADAYVSGSRHITAPSKPAPADQPAWNAQKNSSMPAYRYRPFAEEVEPVTLPDRTWPDKVI 63

Query: 67  ETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 126
           + AP WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTD+DFVREI
Sbjct: 64  DRAPGWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDYDFVREI 123

Query: 127 IEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXX 186
           IEDNAIPDDVTIQVLTQ RPELI RTFEAC GA NVIVHFYNSTSILQRRVVFR      
Sbjct: 124 IEDNAIPDDVTIQVLTQCRPELIERTFEACAGAANVIVHFYNSTSILQRRVVFRADREQV 183

Query: 187 XXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVI 246
                   +L LE  K+YPDTNWR+EYSPESYTGTEL YA+EVCDAV+EI+  TP+ P+I
Sbjct: 184 KKIATDAAKLCLEVEKRYPDTNWRYEYSPESYTGTELEYAREVCDAVSEIIAPTPEKPLI 243

Query: 247 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 306
           +NLPATVEMATPNVYADSIEWM RNLARR+S++LSLHPHNDRGT VAAAELGYQAGADRI
Sbjct: 244 INLPATVEMATPNVYADSIEWMSRNLARRESIVLSLHPHNDRGTAVAAAELGYQAGADRI 303

Query: 307 EGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 366
           EGCLFGNGERTGNVCLVTLG+NMFSRG+DPQIDFS+IDEIRRTVEYCNQLPVHERHPYGG
Sbjct: 304 EGCLFGNGERTGNVCLVTLGMNMFSRGIDPQIDFSDIDEIRRTVEYCNQLPVHERHPYGG 363

Query: 367 DLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRV 426
           DLVYTAFSGSHQDAINKGLD MK            I+W+VPYLPIDPKDVGRTYEAVIRV
Sbjct: 364 DLVYTAFSGSHQDAINKGLDAMKAAADAQNADVSDIVWEVPYLPIDPKDVGRTYEAVIRV 423

Query: 427 NSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAP 486
           NSQSGKGGVAYIMK DHGLVLPRRLQIEFSQV+Q+ITDGEGGEV+PKEMWD F EEYLAP
Sbjct: 424 NSQSGKGGVAYIMKTDHGLVLPRRLQIEFSQVVQKITDGEGGEVTPKEMWDVFHEEYLAP 483

Query: 487 ITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNV 546
           I PLER+RQKV AAE DGG D ITAVVKV+G E+EI G GNGPLAAF DA+  +G +V V
Sbjct: 484 IRPLERIRQKVTAAETDGGVDSITAVVKVDGVEQEITGQGNGPLAAFVDAIATVGYDVRV 543

Query: 547 RDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
            DYSEH                 I  K VWGVGIATSITT
Sbjct: 544 LDYSEHAMSAGDDAQAAAYVECAIGDKVVWGVGIATSITT 583


>tr|D5P919|D5P919_9MYCO Tax_Id=525368 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium parascrofulaceum ATCC
           BAA-614]
          Length = 598

 Score =  900 bits (2326), Expect = 0.0
 Identities = 443/578 (76%), Positives = 481/578 (83%)

Query: 9   DAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVIET 68
           DA+++ R+I  P+G P PGQP WN QRGS+MPV+RYRSFADEVE I LPDRTWP++VI+ 
Sbjct: 6   DAYTSQRSIVKPAGPPAPGQPGWNPQRGSAMPVNRYRSFADEVEPIRLPDRTWPERVIDR 65

Query: 69  APMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIE 128
           AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 
Sbjct: 66  APLWCAVDLRDGNQALIDPMSPTRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIT 125

Query: 129 DNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXXXX 188
           D AIPDDVTIQVLTQ RPELI RTF AC GA   IVHFYNSTSILQRRVVFR        
Sbjct: 126 DGAIPDDVTIQVLTQCRPELIERTFLACEGAPRAIVHFYNSTSILQRRVVFRADRAAVQA 185

Query: 189 XXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVILN 248
                    +EEA KYP T WR+EYSPESYTGTEL YA++VCDAV EI+  TP+NP+I N
Sbjct: 186 IATDGARKCVEEAAKYPGTQWRFEYSPESYTGTELEYARQVCDAVGEIIAPTPENPIIFN 245

Query: 249 LPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRIEG 308
           LPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AGADRIEG
Sbjct: 246 LPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAGADRIEG 305

Query: 309 CLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL 368
           CLFGNGERTGNVCLVTLGLN+FSRGVDPQ+DFSNIDEIRRTVEYCNQLPV ERHPYGGDL
Sbjct: 306 CLFGNGERTGNVCLVTLGLNLFSRGVDPQVDFSNIDEIRRTVEYCNQLPVPERHPYGGDL 365

Query: 369 VYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRVNS 428
           VYTAFSGSHQDAINKGLDQMK+           +LWQVPYLPIDPKDVGRTYEAVIRVNS
Sbjct: 366 VYTAFSGSHQDAINKGLDQMKIDADAADADVDDMLWQVPYLPIDPKDVGRTYEAVIRVNS 425

Query: 429 QSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAPIT 488
           QSGKGGVAYIMK+DHGL LPRRLQIEFSQ IQ+IT+GEGGEVSPKEMWDAF EEYLAP+ 
Sbjct: 426 QSGKGGVAYIMKSDHGLALPRRLQIEFSQAIQKITEGEGGEVSPKEMWDAFYEEYLAPVW 485

Query: 489 PLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNVRD 548
           PLERM+Q+V+A+EED GT  I A VKVNG E E+ GAGNGPLAAF  ALG +G +V V D
Sbjct: 486 PLERMKQRVEASEEDSGTTTIAATVKVNGVETEVSGAGNGPLAAFVHALGDVGFDVAVLD 545

Query: 549 YSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           YSEH                 ++G+TVWGVGIA SITT
Sbjct: 546 YSEHAMSAGDDAQAAAYVEASVNGRTVWGVGIAPSITT 583


>tr|D5UN64|D5UN64_TSUPA Tax_Id=521096 SubName:
           Full=2-isopropylmalate synthase;[Tsukamurella
           paurometabola DSM 20162]
          Length = 622

 Score =  894 bits (2311), Expect = 0.0
 Identities = 445/585 (76%), Positives = 489/585 (83%), Gaps = 5/585 (0%)

Query: 7   SSDAFSTGRT-ITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKV 65
           ++D++++G + I+ P+G  +PGQPAWN QR S+MP  RYR FADEVE+ISLPDRTWPD V
Sbjct: 4   AADSYTSGVSKISTPAGPRNPGQPAWNPQRSSAMPNHRYRPFADEVEQISLPDRTWPDNV 63

Query: 66  IETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 125
            +TAP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE
Sbjct: 64  ADTAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 123

Query: 126 IIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXX 185
           IIED AIPDDVTIQVL Q R ELI RTFEAC+GAKNVIVHFYNSTS+LQRRVVFR     
Sbjct: 124 IIEDGAIPDDVTIQVLVQCRDELIERTFEACQGAKNVIVHFYNSTSVLQRRVVFRADKAA 183

Query: 186 XXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPV 245
                      VLEE KKYPDT WR++YSPESYTGTELS+AKEVCDAVTEI+  TP+NP+
Sbjct: 184 IKKIATDAAHKVLEEQKKYPDTAWRYQYSPESYTGTELSFAKEVCDAVTEIIAPTPENPM 243

Query: 246 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 305
           ILNLPATVEMATPNVYADSIEWM RNL RRDSVILSLHPHNDRG GVAAAELGY AGADR
Sbjct: 244 ILNLPATVEMATPNVYADSIEWMSRNLDRRDSVILSLHPHNDRGEGVAAAELGYLAGADR 303

Query: 306 IEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 365
           IEGCLFGNGERTGNVCLVTLGLNMFSRG+DPQI+F++IDEIRRTVEYCNQLPV ERHPYG
Sbjct: 304 IEGCLFGNGERTGNVCLVTLGLNMFSRGIDPQINFADIDEIRRTVEYCNQLPVPERHPYG 363

Query: 366 GDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIR 425
           GDLVYTAFSGSHQDAINKGLDQMK+           ILWQVPYLPIDPKDVGR+YEAVIR
Sbjct: 364 GDLVYTAFSGSHQDAINKGLDQMKIDADEADKDVDDILWQVPYLPIDPKDVGRSYEAVIR 423

Query: 426 VNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLA 485
           VNSQSGKGGVAYIMK+DHGL LPRRLQIEFSQ +Q+ITDGEGGEV+PKEMWD F+ EY+ 
Sbjct: 424 VNSQSGKGGVAYIMKSDHGLALPRRLQIEFSQSVQKITDGEGGEVTPKEMWDVFAGEYID 483

Query: 486 PITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVN 545
           PI PLERMRQKV A+E DG  D+I AVVKV G+E+EI G GNGPLAAF DA+G +G +V 
Sbjct: 484 PILPLERMRQKVTASEIDGAVDRIEAVVKVEGKEQEISGEGNGPLAAFVDAIGTVGFDVR 543

Query: 546 VRDYSEHXXXXXXXXXXXXXXXXXI----DGKTVWGVGIATSITT 586
           V DYSEH                 +    + +TVWGVGIA SITT
Sbjct: 544 VLDYSEHALSAGDDAQAAAYVEAIVRVGDEDRTVWGVGIAPSITT 588


>tr|B2HKD3|B2HKD3_MYCMM Tax_Id=216594 (leuA)SubName:
           Full=2-isopropylmalate synthase LeuA;[Mycobacterium
           marinum]
          Length = 606

 Score =  893 bits (2308), Expect = 0.0
 Identities = 443/581 (76%), Positives = 480/581 (82%), Gaps = 3/581 (0%)

Query: 9   DAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVIET 68
           DAF++ RTI  P+G P PGQP WN QR SSMPV+RYR FA+EVE I + DRTWPD+VI+ 
Sbjct: 11  DAFTSARTIVKPAGPPSPGQPVWNPQRASSMPVNRYRPFAEEVEHIRVTDRTWPDRVIDR 70

Query: 69  APMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIE 128
           AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 
Sbjct: 71  APLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIT 130

Query: 129 DNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXXXX 188
           + AIPDDVTIQVLTQ RPELI RTFEAC GA  VIVHFYNSTSILQRRVVFR        
Sbjct: 131 EGAIPDDVTIQVLTQCRPELIERTFEACAGASKVIVHFYNSTSILQRRVVFRADRAAVQA 190

Query: 189 XXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVILN 248
                    +EEA KYPDT WR+EYSPESYTGTEL YAK+VCDAV E++  TP+NP+I N
Sbjct: 191 IATEGARRCVEEAAKYPDTQWRFEYSPESYTGTELEYAKQVCDAVAEVIQPTPENPIIFN 250

Query: 249 LPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRIEG 308
           LPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AGADRIEG
Sbjct: 251 LPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAGADRIEG 310

Query: 309 CLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDL 368
           CLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPV ERHPYGGDL
Sbjct: 311 CLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVPERHPYGGDL 370

Query: 369 VYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRVNS 428
           VYTAFSGSHQDAINKGLD MK            +LWQVPYLPIDPKDVGRTYEAVIRVNS
Sbjct: 371 VYTAFSGSHQDAINKGLDAMKFDADAADSDMDDMLWQVPYLPIDPKDVGRTYEAVIRVNS 430

Query: 429 QSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITD---GEGGEVSPKEMWDAFSEEYLA 485
           QSGKGGVAYIMKADHGL LPRRLQIEFS+ IQ+I +   GEGGEVSPKEMWDAF+EEYLA
Sbjct: 431 QSGKGGVAYIMKADHGLALPRRLQIEFSRAIQEIAEGSAGEGGEVSPKEMWDAFAEEYLA 490

Query: 486 PITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVN 545
           P+ PLER++Q+V AAEEDGGT  I A VK++G+E EI G+GNGPLAAF  ALG++G +V 
Sbjct: 491 PVRPLERIKQRVIAAEEDGGTTSIDATVKIDGKETEISGSGNGPLAAFVHALGSVGFDVA 550

Query: 546 VRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           V DYSEH                 + GKTVWGVGIA SITT
Sbjct: 551 VLDYSEHAMSAGDDAQAAAYVEASVAGKTVWGVGIAPSITT 591


>sp|Q9CB76|LEU1_MYCLE Tax_Id=1769 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthase;[Mycobacterium leprae]
          Length = 607

 Score =  881 bits (2277), Expect = 0.0
 Identities = 435/579 (75%), Positives = 472/579 (81%)

Query: 8   SDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVIE 67
           +DA+ +  +IT P G P PGQP WN QR +SMPV RYR FA EVE I L DRTWPD+VI+
Sbjct: 13  ADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72

Query: 68  TAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 127
            AP+WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII
Sbjct: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132

Query: 128 EDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXXX 187
            D  IPDDVTIQVLTQ RPELI RTFEAC  A  VIVHFYNSTSILQRRVVFR       
Sbjct: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192

Query: 188 XXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVIL 247
                     +EEA KYP T+WR+EYSPESYTGTEL YAK+VCDAV E++  TPDNP+I 
Sbjct: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252

Query: 248 NLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRIE 307
           NLPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELGY AGADRIE
Sbjct: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312

Query: 308 GCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGD 367
           GCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYGGD
Sbjct: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372

Query: 368 LVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRVN 427
           LVYTAFSGSHQDAINKGLDQMK+           ILWQVPYLPIDP+DVGRTYEAVIRVN
Sbjct: 373 LVYTAFSGSHQDAINKGLDQMKIDADAADSDVDDILWQVPYLPIDPRDVGRTYEAVIRVN 432

Query: 428 SQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAPI 487
           SQSGKGGVAYIMKADHGL LPRRLQIEFS+ IQ+I++GEGGE++P EMWD F EEYL+P+
Sbjct: 433 SQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPV 492

Query: 488 TPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNVR 547
            PLER++Q+V+AAEEDGG+  I A VK+NGEE EI G GNGPLAAF DALG +G+ V V 
Sbjct: 493 QPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVL 552

Query: 548 DYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           DYSEH                 + G T WGVGIA SITT
Sbjct: 553 DYSEHAMNAGDDAQAAAYVEASVHGHTAWGVGIAPSITT 591


>tr|B8ZT16|B8ZT16_MYCLB Tax_Id=561304 (leuA)SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium leprae]
          Length = 607

 Score =  881 bits (2277), Expect = 0.0
 Identities = 435/579 (75%), Positives = 472/579 (81%)

Query: 8   SDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVIE 67
           +DA+ +  +IT P G P PGQP WN QR +SMPV RYR FA EVE I L DRTWPD+VI+
Sbjct: 13  ADAYKSAPSITKPMGPPSPGQPQWNPQRATSMPVFRYRPFAKEVEPIRLVDRTWPDRVID 72

Query: 68  TAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 127
            AP+WCAVDLRDGNQALIDPMSP  KRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII
Sbjct: 73  CAPLWCAVDLRDGNQALIDPMSPICKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREII 132

Query: 128 EDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXXX 187
            D  IPDDVTIQVLTQ RPELI RTFEAC  A  VIVHFYNSTSILQRRVVFR       
Sbjct: 133 TDGTIPDDVTIQVLTQCRPELIERTFEACENASRVIVHFYNSTSILQRRVVFRADQATVK 192

Query: 188 XXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVIL 247
                     +EEA KYP T+WR+EYSPESYTGTEL YAK+VCDAV E++  TPDNP+I 
Sbjct: 193 AIATDGARKCVEEAFKYPGTHWRFEYSPESYTGTELEYAKQVCDAVGEVIQPTPDNPIIF 252

Query: 248 NLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRIE 307
           NLPATVEMATPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELGY AGADRIE
Sbjct: 253 NLPATVEMATPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGYHAGADRIE 312

Query: 308 GCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGD 367
           GCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCN+L VHERHPYGGD
Sbjct: 313 GCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNKLRVHERHPYGGD 372

Query: 368 LVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIRVN 427
           LVYTAFSGSHQDAINKGLDQMK+           ILWQVPYLPIDP+DVGRTYEAVIRVN
Sbjct: 373 LVYTAFSGSHQDAINKGLDQMKIDADAADSDVDDILWQVPYLPIDPRDVGRTYEAVIRVN 432

Query: 428 SQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLAPI 487
           SQSGKGGVAYIMKADHGL LPRRLQIEFS+ IQ+I++GEGGE++P EMWD F EEYL+P+
Sbjct: 433 SQSGKGGVAYIMKADHGLELPRRLQIEFSRAIQKISEGEGGEITPTEMWDVFFEEYLSPV 492

Query: 488 TPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVNVR 547
            PLER++Q+V+AAEEDGG+  I A VK+NGEE EI G GNGPLAAF DALG +G+ V V 
Sbjct: 493 QPLERIKQRVNAAEEDGGSTSIAATVKINGEETEISGVGNGPLAAFIDALGHVGLQVAVL 552

Query: 548 DYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSITT 586
           DYSEH                 + G T WGVGIA SITT
Sbjct: 553 DYSEHAMNAGDDAQAAAYVEASVHGHTAWGVGIAPSITT 591


>tr|B1MFN6|B1MFN6_MYCA9 Tax_Id=561007 SubName: Full=Probable
           2-isopropylmalate synthase (LeuA);[Mycobacterium
           abscessus]
          Length = 607

 Score =  878 bits (2269), Expect = 0.0
 Identities = 441/587 (75%), Positives = 478/587 (81%), Gaps = 7/587 (1%)

Query: 7   SSDAFS-TGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKV 65
           SSD F+ T R++  P+G     QPAWNTQ+ SSMPV RYRSF DEVEKI LPDRTWPDKV
Sbjct: 5   SSDEFNYTPRSVVTPNGPIPADQPAWNTQKNSSMPVHRYRSFTDEVEKIELPDRTWPDKV 64

Query: 66  IETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 125
           I  AP W AVDLRDGNQALIDPMSP RKRRMFDL +RMG+KEIEVGFPSASQTDFDF+RE
Sbjct: 65  ITRAPQWGAVDLRDGNQALIDPMSPARKRRMFDLQIRMGFKEIEVGFPSASQTDFDFIRE 124

Query: 126 IIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXX 185
           +I +NAIPDDVTIQVLTQ RPELI RTF AC GA  VIVHFYNSTSILQRRVVFR     
Sbjct: 125 LITENAIPDDVTIQVLTQCRPELIERTFLACEGASKVIVHFYNSTSILQRRVVFREDKDA 184

Query: 186 XXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPV 245
                       +EEA KYPDT+WR++YSPESYTGTEL YA EVC+AV +I+  TPDNP+
Sbjct: 185 IKKIATDGAHKCVEEAAKYPDTHWRFQYSPESYTGTELQYALEVCNAVGDIVEPTPDNPI 244

Query: 246 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 305
           I NLP+TVEM TPNVYADSIEWM RNLARRDSVILSLHPHNDRGT VAAAELG+QAGADR
Sbjct: 245 IFNLPSTVEMTTPNVYADSIEWMSRNLARRDSVILSLHPHNDRGTAVAAAELGFQAGADR 304

Query: 306 IEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 365
           IEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIR TVEYCNQL V ERHPYG
Sbjct: 305 IEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRHTVEYCNQLKVPERHPYG 364

Query: 366 GDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVIR 425
           GDLVYTAFSGSHQDAINKGLDQMK            ILWQVPYLPIDPKDVGR YEAVIR
Sbjct: 365 GDLVYTAFSGSHQDAINKGLDQMKRDADEADSDVDDILWQVPYLPIDPKDVGRNYEAVIR 424

Query: 426 VNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYLA 485
           VNSQSGKGGVAYIMK+DHGLVLPRRLQIEF+Q IQ+ITDGEGGEV+PKE+WD F+EEYLA
Sbjct: 425 VNSQSGKGGVAYIMKSDHGLVLPRRLQIEFAQSIQRITDGEGGEVNPKEIWDVFAEEYLA 484

Query: 486 PITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINVN 545
           PITPLER+RQKV A+EEDGGTD I AVVK++G+E E+ G GNGPLAAF DAL  +G  VN
Sbjct: 485 PITPLERIRQKVTASEEDGGTDSIAAVVKIDGKETEVNGTGNGPLAAFVDALSTVGYTVN 544

Query: 546 VRDYSEHXXXXXXXXXXXXXXXXXI------DGKTVWGVGIATSITT 586
           V DYSEH                 +      + +TVWGVGIA SITT
Sbjct: 545 VLDYSEHALSAGDDAQAAAYVEATVVSPGGGEAQTVWGVGIAPSITT 591


>sp|P96420|LEU1_MYCTU Tax_Id=1773 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthase;[Mycobacterium tuberculosis]
          Length = 644

 Score =  857 bits (2213), Expect = 0.0
 Identities = 437/625 (69%), Positives = 475/625 (76%), Gaps = 42/625 (6%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXI----------------------------- 570
           +G +V V DY EH                 +                             
Sbjct: 545 VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGE 604

Query: 571 ---------DGKTVWGVGIATSITT 586
                      KTVWGVGIA SITT
Sbjct: 605 AGRHASDPVTSKTVWGVGIAPSITT 629


>tr|C6DNF0|C6DNF0_MYCTK Tax_Id=478434 SubName:
           Full=2-isopropylmalate synthase leuA;[Mycobacterium
           tuberculosis]
          Length = 644

 Score =  857 bits (2213), Expect = 0.0
 Identities = 437/625 (69%), Positives = 475/625 (76%), Gaps = 42/625 (6%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXI----------------------------- 570
           +G +V V DY EH                 +                             
Sbjct: 545 VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGE 604

Query: 571 ---------DGKTVWGVGIATSITT 586
                      KTVWGVGIA SITT
Sbjct: 605 AGRHASDPVTSKTVWGVGIAPSITT 629


>tr|A5WTS8|A5WTS8_MYCTF Tax_Id=336982 SubName:
           Full=2-isopropylmalate synthase leuA;[Mycobacterium
           tuberculosis]
          Length = 644

 Score =  857 bits (2213), Expect = 0.0
 Identities = 437/625 (69%), Positives = 475/625 (76%), Gaps = 42/625 (6%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXI----------------------------- 570
           +G +V V DY EH                 +                             
Sbjct: 545 VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGE 604

Query: 571 ---------DGKTVWGVGIATSITT 586
                      KTVWGVGIA SITT
Sbjct: 605 AGRHASDPVTSKTVWGVGIAPSITT 629


>tr|A5U936|A5U936_MYCTA Tax_Id=419947 (leuA)SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           tuberculosis]
          Length = 644

 Score =  857 bits (2213), Expect = 0.0
 Identities = 437/625 (69%), Positives = 475/625 (76%), Gaps = 42/625 (6%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXI----------------------------- 570
           +G +V V DY EH                 +                             
Sbjct: 545 VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGE 604

Query: 571 ---------DGKTVWGVGIATSITT 586
                      KTVWGVGIA SITT
Sbjct: 605 AGRHASDPVTSKTVWGVGIAPSITT 629


>tr|D6G5I6|D6G5I6_MYCTU Tax_Id=478435 SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           tuberculosis KZN 605]
          Length = 644

 Score =  857 bits (2213), Expect = 0.0
 Identities = 437/625 (69%), Positives = 475/625 (76%), Gaps = 42/625 (6%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXI----------------------------- 570
           +G +V V DY EH                 +                             
Sbjct: 545 VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGE 604

Query: 571 ---------DGKTVWGVGIATSITT 586
                      KTVWGVGIA SITT
Sbjct: 605 AGRHASDPVTSKTVWGVGIAPSITT 629


>tr|D5ZAT5|D5ZAT5_MYCTU Tax_Id=537209 SubName:
           Full=2-isopropylmalate synthase leuA;[Mycobacterium
           tuberculosis GM 1503]
          Length = 644

 Score =  857 bits (2213), Expect = 0.0
 Identities = 437/625 (69%), Positives = 475/625 (76%), Gaps = 42/625 (6%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXI----------------------------- 570
           +G +V V DY EH                 +                             
Sbjct: 545 VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGE 604

Query: 571 ---------DGKTVWGVGIATSITT 586
                      KTVWGVGIA SITT
Sbjct: 605 AGRHASDPVTSKTVWGVGIAPSITT 629


>tr|D5YXY3|D5YXY3_MYCTU Tax_Id=515616 SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           tuberculosis 02_1987]
          Length = 644

 Score =  857 bits (2213), Expect = 0.0
 Identities = 437/625 (69%), Positives = 475/625 (76%), Gaps = 42/625 (6%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXI----------------------------- 570
           +G +V V DY EH                 +                             
Sbjct: 545 VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGE 604

Query: 571 ---------DGKTVWGVGIATSITT 586
                      KTVWGVGIA SITT
Sbjct: 605 AGRHASDPVTSKTVWGVGIAPSITT 629


>tr|D5Y9W2|D5Y9W2_MYCTU Tax_Id=520141 SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           tuberculosis T85]
          Length = 644

 Score =  857 bits (2213), Expect = 0.0
 Identities = 437/625 (69%), Positives = 475/625 (76%), Gaps = 42/625 (6%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXI----------------------------- 570
           +G +V V DY EH                 +                             
Sbjct: 545 VGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGE 604

Query: 571 ---------DGKTVWGVGIATSITT 586
                      KTVWGVGIA SITT
Sbjct: 605 AGRHASDPVTSKTVWGVGIAPSITT 629


>sp|Q7TVV6|LEU1_MYCBO Tax_Id=1765 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthase;[Mycobacterium bovis]
          Length = 701

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/553 (76%), Positives = 461/553 (83%), Gaps = 4/553 (0%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAHRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEH 552
           +G +V V DY EH
Sbjct: 545 VGFDVAVLDYYEH 557


>tr|C1AIG4|C1AIG4_MYCBT Tax_Id=561275 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Mycobacterium bovis]
          Length = 815

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/553 (76%), Positives = 461/553 (83%), Gaps = 4/553 (0%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAHRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEH 552
           +G +V V DY EH
Sbjct: 545 VGFDVAVLDYYEH 557


>tr|A1KQ42|A1KQ42_MYCBP Tax_Id=410289 (leuA)SubName:
           Full=2-isopropylmalate synthase leuA;
           EC=2.3.3.13;[Mycobacterium bovis]
          Length = 834

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/553 (76%), Positives = 461/553 (83%), Gaps = 4/553 (0%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAHRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEH 552
           +G +V V DY EH
Sbjct: 545 VGFDVAVLDYYEH 557


>tr|D6FTX5|D6FTX5_MYCTU Tax_Id=611304 SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           tuberculosis K85]
          Length = 697

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/553 (76%), Positives = 461/553 (83%), Gaps = 4/553 (0%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 21  SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 79

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 80  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 139

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 140 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 199

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 200 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 259

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 260 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 319

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 320 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 379

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 380 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 439

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 440 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 499

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 500 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 559

Query: 540 LGINVNVRDYSEH 552
           +G +V V DY EH
Sbjct: 560 VGFDVAVLDYYEH 572


>tr|D6FAR4|D6FAR4_MYCTU Tax_Id=611303 SubName:
           Full=2-isopropylmalate synthase;[Mycobacterium
           tuberculosis CPHL_A]
          Length = 700

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/553 (76%), Positives = 461/553 (83%), Gaps = 4/553 (0%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 24  SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 82

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 83  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 142

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 143 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 202

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 203 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 262

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 263 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 322

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 323 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 382

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 383 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 442

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 443 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 502

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 503 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 562

Query: 540 LGINVNVRDYSEH 552
           +G +V V DY EH
Sbjct: 563 VGFDVAVLDYYEH 575


>tr|D6EZ63|D6EZ63_MYCTU Tax_Id=611302 SubName:
           Full=2-isopropylmalate synthase; Flags:
           Fragment;[Mycobacterium tuberculosis T46]
          Length = 701

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/553 (76%), Positives = 461/553 (83%), Gaps = 4/553 (0%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 13  SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 71

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 72  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 131

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 132 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 191

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 192 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 251

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 252 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 311

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 312 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 371

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 372 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 431

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 432 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 491

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 492 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 551

Query: 540 LGINVNVRDYSEH 552
           +G +V V DY EH
Sbjct: 552 VGFDVAVLDYYEH 564


>tr|D5ZMQ6|D5ZMQ6_MYCTU Tax_Id=537210 SubName:
           Full=2-isopropylmalate synthase leuA; Flags:
           Fragment;[Mycobacterium tuberculosis T17]
          Length = 695

 Score =  856 bits (2211), Expect = 0.0
 Identities = 424/553 (76%), Positives = 461/553 (83%), Gaps = 4/553 (0%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 6   SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 64

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 65  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 124

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 125 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 184

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 185 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 244

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 245 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 304

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 305 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 364

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 365 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 424

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 425 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 485 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 544

Query: 540 LGINVNVRDYSEH 552
           +G +V V DY EH
Sbjct: 545 VGFDVAVLDYYEH 557


>tr|D5XNL4|D5XNL4_MYCTU Tax_Id=515617 SubName:
           Full=2-isopropylmalate synthase leuA;[Mycobacterium
           tuberculosis T92]
          Length = 678

 Score =  854 bits (2206), Expect = 0.0
 Identities = 423/553 (76%), Positives = 461/553 (83%), Gaps = 4/553 (0%)

Query: 3   TPDISSDAFSTGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWP 62
           +PD  +++F    TI  P+G P  GQP+WN QR SSMPV+RYR FA+EVE I L +RTWP
Sbjct: 21  SPDAYTESFGA-HTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWP 79

Query: 63  DKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 122
           D+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFDLLVRMGYKEIEVGFPSASQTDFDF
Sbjct: 80  DRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDF 139

Query: 123 VREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXX 182
           VREIIE  AIPDDVTIQVLTQ RPELI RTF+AC GA   IVHFYNSTSILQRRVVFR  
Sbjct: 140 VREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRAN 199

Query: 183 XXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPD 242
                          +E+A KYP T WR+EYSPESYTGTEL YAK+VCDAV E++  TP+
Sbjct: 200 RAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPE 259

Query: 243 NPVILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAG 302
            P+I NLPATVEM TPNVYADSIEWM RNLA R+SVILSLHPHNDRGT VAAAELG+ AG
Sbjct: 260 RPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAG 319

Query: 303 ADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 362
           ADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH
Sbjct: 320 ADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERH 379

Query: 363 PYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEA 422
           PYGGDLVYTAFSGSHQDAINKGLD MK+           +LWQVPYLPIDP+DVGRTYEA
Sbjct: 380 PYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEA 439

Query: 423 VIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQI---TDGEGGEVSPKEMWDAF 479
           VIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQVIQ+I   T GEGGEVSPKEMWDAF
Sbjct: 440 VIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAF 499

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+NG E EI G+GNGPLAAF  AL  
Sbjct: 500 AEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALAD 559

Query: 540 LGINVNVRDYSEH 552
           +G +V V +Y EH
Sbjct: 560 VGFDVAVLNYYEH 572


>sp|A0PVE6|LEU1_MYCUA Tax_Id=362242 (leuA)RecName:
           Full=2-isopropylmalate synthase; EC=2.3.3.13; AltName:
           Full=Alpha-isopropylmalate synthase; AltName:
           Full=Alpha-IPM synthase;[Mycobacterium ulcerans]
          Length = 566

 Score =  848 bits (2190), Expect = 0.0
 Identities = 422/551 (76%), Positives = 456/551 (82%), Gaps = 3/551 (0%)

Query: 39  MPVSRYRSFADEVEKISLPDRTWPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFD 98
           MPV+RYR FA+EVE I + DRTWPD+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFD
Sbjct: 1   MPVNRYRPFAEEVEHIRVTDRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFD 60

Query: 99  LLVRMGYKEIEVGFPSASQTDFDFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRG 158
           LLVRMGYKEIEVGFPSASQTDFDFVREII + AIPDDVTIQVLTQ RPELI RTFEAC G
Sbjct: 61  LLVRMGYKEIEVGFPSASQTDFDFVREIITEGAIPDDVTIQVLTQCRPELIERTFEACAG 120

Query: 159 AKNVIVHFYNSTSILQRRVVFRXXXXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESY 218
           A  VIVHFYNSTSILQRRVVFR                 +EEA KYPDT WR+EYSPESY
Sbjct: 121 ASKVIVHFYNSTSILQRRVVFRADRAAVEAIATDGARRCVEEAAKYPDTQWRFEYSPESY 180

Query: 219 TGTELSYAKEVCDAVTEILGATPDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSV 278
           TGTEL YAK+VCDAV E++  TP+NP+I NLPATVEMATPNVYADSIEWM RNLA R+SV
Sbjct: 181 TGTELEYAKQVCDAVAEVIQPTPENPIIFNLPATVEMATPNVYADSIEWMSRNLANRESV 240

Query: 279 ILSLHPHNDRGTGVAAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQI 338
           ILSLHPHNDRGT VAAAELG+ AGADRIEGCLFGNGERTGNVCL TLGLN+FSRGVDPQI
Sbjct: 241 ILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLATLGLNLFSRGVDPQI 300

Query: 339 DFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXX 398
           DFSNIDEIRRTVEYCNQLPV ERHPYGGDLVYTAFSGSHQDAINKGLD M+         
Sbjct: 301 DFSNIDEIRRTVEYCNQLPVPERHPYGGDLVYTAFSGSHQDAINKGLDAMEFDADAADSD 360

Query: 399 XXXILWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQV 458
              +LWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGL LPRRLQIEFS+ 
Sbjct: 361 MDDMLWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLALPRRLQIEFSRA 420

Query: 459 IQQITD---GEGGEVSPKEMWDAFSEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKV 515
           IQ+I +   GEGGEVSPKEMWDAF+EEYLAP+ PLER++Q+V AAEEDGGT  I A VK+
Sbjct: 421 IQEIAEGSAGEGGEVSPKEMWDAFAEEYLAPVRPLERIKQRVIAAEEDGGTTSIDATVKI 480

Query: 516 NGEEREIVGAGNGPLAAFCDALGALGINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTV 575
           +G+E EI G+GNGPLAAF  ALG +G +V V DYSEH                 + GKTV
Sbjct: 481 DGKEAEISGSGNGPLAAFVHALGTVGFDVAVLDYSEHAMSAGDDAQAAAYVEASVAGKTV 540

Query: 576 WGVGIATSITT 586
           WGVGIA SITT
Sbjct: 541 WGVGIAPSITT 551


>tr|D5YLG0|D5YLG0_MYCTU Tax_Id=520140 SubName:
           Full=2-isopropylmalate synthase leuA;[Mycobacterium
           tuberculosis EAS054]
          Length = 756

 Score =  822 bits (2123), Expect = 0.0
 Identities = 407/517 (78%), Positives = 438/517 (84%), Gaps = 3/517 (0%)

Query: 39  MPVSRYRSFADEVEKISLPDRTWPDKVIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFD 98
           MPV+RYR FA+EVE I L +RTWPD+VI+ AP+WCAVDLRDGNQALIDPMSP RKRRMFD
Sbjct: 1   MPVNRYRPFAEEVEPIRLRNRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFD 60

Query: 99  LLVRMGYKEIEVGFPSASQTDFDFVREIIEDNAIPDDVTIQVLTQSRPELITRTFEACRG 158
           LLVRMGYKEIEVGFPSASQTDFDFVREIIE  AIPDDVTIQVLTQ RPELI RTF+AC G
Sbjct: 61  LLVRMGYKEIEVGFPSASQTDFDFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSG 120

Query: 159 AKNVIVHFYNSTSILQRRVVFRXXXXXXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESY 218
           A   IVHFYNSTSILQRRVVFR                 +E+A KYP T WR+EYSPESY
Sbjct: 121 APRAIVHFYNSTSILQRRVVFRANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESY 180

Query: 219 TGTELSYAKEVCDAVTEILGATPDNPVILNLPATVEMATPNVYADSIEWMHRNLARRDSV 278
           TGTEL YAK+VCDAV E++  TP+ P+I NLPATVEM TPNVYADSIEWM RNLA R+SV
Sbjct: 181 TGTELEYAKQVCDAVGEVIAPTPERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESV 240

Query: 279 ILSLHPHNDRGTGVAAAELGYQAGADRIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQI 338
           ILSLHPHNDRGT VAAAELG+ AGADRIEGCLFGNGERTGNVCLVTLGLN+FSRGVDPQI
Sbjct: 241 ILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQI 300

Query: 339 DFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXX 398
           DFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLD MK+        
Sbjct: 301 DFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCD 360

Query: 399 XXXILWQVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQV 458
              +LWQVPYLPIDP+DVGRTYEAVIRVNSQSGKGGVAYIMK DHGL LPRRLQIEFSQV
Sbjct: 361 VDDMLWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQV 420

Query: 459 IQQI---TDGEGGEVSPKEMWDAFSEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKV 515
           IQ+I   T GEGGEVSPKEMWDAF+EEYLAP+ PLER+RQ VDAA++DGGT  ITA VK+
Sbjct: 421 IQKIAEGTAGEGGEVSPKEMWDAFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKI 480

Query: 516 NGEEREIVGAGNGPLAAFCDALGALGINVNVRDYSEH 552
           NG E EI G+GNGPLAAF  AL  +G +V V DY EH
Sbjct: 481 NGVETEISGSGNGPLAAFVHALADVGFDVAVLDYYEH 517


>tr|C6WF52|C6WF52_ACTMD Tax_Id=446462 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Actinosynnema mirum]
          Length = 598

 Score =  808 bits (2086), Expect = 0.0
 Identities = 393/579 (67%), Positives = 460/579 (79%), Gaps = 3/579 (0%)

Query: 6   ISSDAFSTGRTITPPSGAPHP-GQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDK 64
           IS DA+STG +   P   P P GQPAWN QRG+SMPV RYR F + VE + LPDRTWP K
Sbjct: 4   ISPDAYSTGTSRIRPPARPAPEGQPAWNPQRGTSMPVHRYRPFHELVETVDLPDRTWPAK 63

Query: 65  VIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVR 124
            I  AP WCAVDLRDGNQALIDPMSP RKR+MFDLLVRMGYKEIEVGFP+ASQTDFDFVR
Sbjct: 64  RITQAPQWCAVDLRDGNQALIDPMSPARKRKMFDLLVRMGYKEIEVGFPAASQTDFDFVR 123

Query: 125 EIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXX 184
           EIIED A+PDDVTIQVLTQ RPELITRT+E+ RGA   IVHFYNSTS+LQR+VVFR    
Sbjct: 124 EIIEDGAVPDDVTIQVLTQCRPELITRTYESLRGAHKAIVHFYNSTSVLQRKVVFRADRD 183

Query: 185 XXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNP 244
                        LEEAKKYP+T +R+EYSPESYTGTELSYA EVCDAV+EI+  TP+ P
Sbjct: 184 RIKAIATDAARFALEEAKKYPETEFRYEYSPESYTGTELSYALEVCDAVSEIIAPTPELP 243

Query: 245 VILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGAD 304
           +++NLPATVEMATPNVYADSIEWM R+LARRDS++LSLHPHNDRGTGVAAAELGY AGAD
Sbjct: 244 MVINLPATVEMATPNVYADSIEWMSRHLARRDSIVLSLHPHNDRGTGVAAAELGYLAGAD 303

Query: 305 RIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPY 364
           RIEGCLFGNGERTGNVCLVTLG+NMFS+GVDPQIDFS+IDE+RRTVEYCNQLPVHERHPY
Sbjct: 304 RIEGCLFGNGERTGNVCLVTLGMNMFSQGVDPQIDFSDIDEVRRTVEYCNQLPVHERHPY 363

Query: 365 GGDLVYTAFSGSHQDAINKGLDQMKVXXXXXXXXXXXILWQVPYLPIDPKDVGRTYEAVI 424
           GGDLV+TAFSGSHQDAI KG + ++              W+VPYLPIDPKDVGR YEAVI
Sbjct: 364 GGDLVFTAFSGSHQDAIKKGFEALEADAKDADKHVDEYPWEVPYLPIDPKDVGRNYEAVI 423

Query: 425 RVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAFSEEYL 484
           RVNSQSGKGGVAY+MK++H L LPRRLQ+EFS+VIQ++TD +GGEV PKE+WDAF++EYL
Sbjct: 424 RVNSQSGKGGVAYVMKSEHHLDLPRRLQVEFSRVIQEVTDTQGGEVGPKEIWDAFADEYL 483

Query: 485 APITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGALGINV 544
             + PL  ++ ++  + +  G++ I  V+ V+GE +++ G GNGP+AAF DAL ++G +V
Sbjct: 484 QGVAPLRLLKHEL--SSDGTGSESIKTVLVVDGETQDVTGTGNGPIAAFVDALASVGYDV 541

Query: 545 NVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATS 583
            V DYSEH                 +  + +WGVG+ +S
Sbjct: 542 RVLDYSEHALSSGDDARAASYVECSVGDRVLWGVGVDSS 580


>tr|Q4JSM3|Q4JSM3_CORJK Tax_Id=306537 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium jeikeium]
          Length = 613

 Score =  806 bits (2083), Expect = 0.0
 Identities = 399/588 (67%), Positives = 454/588 (77%), Gaps = 8/588 (1%)

Query: 6   ISSDAF-STGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDK 64
           +S+D F S    I  P+G    GQPAWN QR SSMP  RY+ F +EVE+I+LPDRTWPDK
Sbjct: 1   MSNDTFISAPARINTPNGEIPEGQPAWNKQRNSSMPHVRYQPFFEEVEEITLPDRTWPDK 60

Query: 65  VIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVR 124
           VI+ AP WCAVDLRDGNQALIDPMSP+RKRRMF+LLV MGYKEIEVGFPSASQTDF+FVR
Sbjct: 61  VIDRAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVDMGYKEIEVGFPSASQTDFNFVR 120

Query: 125 EIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXX 184
           EIIE N IPDDVTIQVL Q+R  LI RTFEAC GAKNVIVHFYNSTS LQR+VVFR    
Sbjct: 121 EIIEKNMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSKLQRKVVFRKDKE 180

Query: 185 XXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNP 244
                     EL+   AK YPDTNWRWEYSPESYTGTE++YAKEVCDAV E++  TP+NP
Sbjct: 181 AIKKLATDAAELIKTIAKDYPDTNWRWEYSPESYTGTEVAYAKEVCDAVVEVMDPTPENP 240

Query: 245 VILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGAD 304
           +ILNLP+TVEM TPNVYADSIEWMHRNL RRDS+ILSLHPHNDRGTGVAAAELGY AGAD
Sbjct: 241 IILNLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGTGVAAAELGYMAGAD 300

Query: 305 RIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPY 364
           RIEGCLFGNGERTGNVCLVTLGLNM ++GVDPQIDFS+ID++RRTVEYCNQL V ERHPY
Sbjct: 301 RIEGCLFGNGERTGNVCLVTLGLNMLTQGVDPQIDFSDIDQVRRTVEYCNQLRVPERHPY 360

Query: 365 GGDLVYTAFSGSHQDAINKGLDQM-------KVXXXXXXXXXXXILWQVPYLPIDPKDVG 417
           GGDLV+TAFSGSHQDAINKGLD +                      W+VPYLPIDPKDVG
Sbjct: 361 GGDLVFTAFSGSHQDAINKGLDAIAEKIDPDATAEEVTQEAMVEKTWEVPYLPIDPKDVG 420

Query: 418 RTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWD 477
           R+YEAVIRVNSQSGKGGVAYIMK DH L LPR +Q+EFS V+Q +TD EGGEV+PK MWD
Sbjct: 421 RSYEAVIRVNSQSGKGGVAYIMKTDHNLQLPRPMQVEFSSVVQAVTDAEGGEVNPKAMWD 480

Query: 478 AFSEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDAL 537
            FS EYL  + P+E +   VD  + +G   K+T  ++ NGE + + G GNGP+ A+C+AL
Sbjct: 481 IFSGEYLDRVAPIETISLTVDGGQNEGEEAKVTGQIEFNGEGKTVQGRGNGPINAYCNAL 540

Query: 538 GALGINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSIT 585
             LG +V V++YS+H                 I+G   WGVGIA+SIT
Sbjct: 541 EELGYDVEVQEYSQHARTSGDDAEAAAYVLAEINGAKYWGVGIASSIT 588


>tr|C8RV49|C8RV49_CORJE Tax_Id=525262 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium jeikeium ATCC 43734]
          Length = 613

 Score =  806 bits (2083), Expect = 0.0
 Identities = 399/588 (67%), Positives = 454/588 (77%), Gaps = 8/588 (1%)

Query: 6   ISSDAF-STGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDK 64
           +S+D F S    I  P+G    GQPAWN QR SSMP  RY+ F +EVE+I+LPDRTWPDK
Sbjct: 1   MSNDTFISAPARINTPNGEIPEGQPAWNKQRNSSMPHVRYQPFFEEVEEITLPDRTWPDK 60

Query: 65  VIETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVR 124
           VI+ AP WCAVDLRDGNQALIDPMSP+RKRRMF+LLV MGYKEIEVGFPSASQTDF+FVR
Sbjct: 61  VIDRAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVDMGYKEIEVGFPSASQTDFNFVR 120

Query: 125 EIIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXX 184
           EIIE N IPDDVTIQVL Q+R  LI RTFEAC GAKNVIVHFYNSTS LQR+VVFR    
Sbjct: 121 EIIEKNMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSKLQRKVVFRKDKE 180

Query: 185 XXXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNP 244
                     EL+   AK YPDTNWRWEYSPESYTGTE++YAKEVCDAV E++  TP+NP
Sbjct: 181 AIKKLATDAAELIKTIAKDYPDTNWRWEYSPESYTGTEVAYAKEVCDAVVEVMDPTPENP 240

Query: 245 VILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGAD 304
           +ILNLP+TVEM TPNVYADSIEWMHRNL RRDS+ILSLHPHNDRGTGVAAAELGY AGAD
Sbjct: 241 IILNLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGTGVAAAELGYMAGAD 300

Query: 305 RIEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPY 364
           RIEGCLFGNGERTGNVCLVTLGLNM ++GVDPQIDFS+ID++RRTVEYCNQL V ERHPY
Sbjct: 301 RIEGCLFGNGERTGNVCLVTLGLNMLTQGVDPQIDFSDIDQVRRTVEYCNQLRVPERHPY 360

Query: 365 GGDLVYTAFSGSHQDAINKGLDQM-------KVXXXXXXXXXXXILWQVPYLPIDPKDVG 417
           GGDLV+TAFSGSHQDAINKGLD +                      W+VPYLPIDPKDVG
Sbjct: 361 GGDLVFTAFSGSHQDAINKGLDAIAEKIDPDATAEEVTQEAMVEKTWEVPYLPIDPKDVG 420

Query: 418 RTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWD 477
           R+YEAVIRVNSQSGKGGVAYIMK DH L LPR +Q+EFS V+Q +TD EGGEV+PK MWD
Sbjct: 421 RSYEAVIRVNSQSGKGGVAYIMKTDHNLQLPRPMQVEFSSVVQAVTDAEGGEVNPKAMWD 480

Query: 478 AFSEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDAL 537
            FS EYL  + P+E +   VD  + +G   K+T  ++ NGE + + G GNGP+ A+C+AL
Sbjct: 481 IFSGEYLDRVAPIETISLTVDGGQNEGEEAKVTGQIEFNGEGKTVQGRGNGPINAYCNAL 540

Query: 538 GALGINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSIT 585
             LG +V V++YS+H                 I+G   WGVGIA+SIT
Sbjct: 541 EELGYDVEVQEYSQHARTSGDDAEAAAYVLAEINGAKYWGVGIASSIT 588


>tr|C5VA14|C5VA14_9CORY Tax_Id=553207 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium matruchotii ATCC 14266]
          Length = 608

 Score =  794 bits (2051), Expect = 0.0
 Identities = 391/586 (66%), Positives = 451/586 (76%), Gaps = 9/586 (1%)

Query: 9   DAFSTGRT--ITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKVI 66
           D F +  T  IT P+G P   QP WN QRGS+MP  RY+ FA EVE ++LPDRTWPD  I
Sbjct: 5   DTFISAPTSDITKPAGEPPADQPKWNKQRGSAMPAHRYQPFAQEVEDVTLPDRTWPDNKI 64

Query: 67  ETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREI 126
             AP WCAVDLRDGNQALIDPMSP+RKRRMF+LLV+MGYKEIEVGFPSASQTDFDFVREI
Sbjct: 65  THAPAWCAVDLRDGNQALIDPMSPERKRRMFNLLVQMGYKEIEVGFPSASQTDFDFVREI 124

Query: 127 IEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXXX 186
           IE + IPDDVTIQVL Q+R  LI RTFEAC GAKNVIVHFYNSTSILQR VVFR      
Sbjct: 125 IEQDMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRNVVFRKDKAAI 184

Query: 187 XXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPVI 246
                   EL+   AK+YPDTNWRWEYSPES+TGTEL+YAKEV DAV E++  TP+NP+I
Sbjct: 185 KKLATDAGELIKTIAKEYPDTNWRWEYSPESFTGTELAYAKEVVDAVVEVMDPTPENPII 244

Query: 247 LNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADRI 306
           +NLP+TVEM TPNVYAD+IEWMHRNL RRDS+ILSLHPHNDRGTGVA+AEL + AGADRI
Sbjct: 245 INLPSTVEMITPNVYADAIEWMHRNLNRRDSIILSLHPHNDRGTGVASAELAFMAGADRI 304

Query: 307 EGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGG 366
           EGCLFGNGERTGNVCLVTLGLN+ ++GVDPQIDF+NI++IR TVEYCNQL V ERHPYGG
Sbjct: 305 EGCLFGNGERTGNVCLVTLGLNLLTQGVDPQIDFTNINQIRSTVEYCNQLRVPERHPYGG 364

Query: 367 DLVYTAFSGSHQDAINKGLDQMKV-------XXXXXXXXXXXILWQVPYLPIDPKDVGRT 419
           DLV+TAFSGSHQDA+NKGLD M                     LW+VPYLPIDPKDVGR 
Sbjct: 365 DLVFTAFSGSHQDAVNKGLDAMAARVHPGANHSDVKWEQLRDELWEVPYLPIDPKDVGRN 424

Query: 420 YEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDAF 479
           YEAVIRVNSQSGKGGVAYIMK DHG+VLPR +Q+EFS V+Q +TD +GGE+  K MWD F
Sbjct: 425 YEAVIRVNSQSGKGGVAYIMKTDHGMVLPRPMQVEFSSVVQDVTDAQGGEIESKAMWDIF 484

Query: 480 SEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALGA 539
           +E YL   TPLE++  +VDAA  +    KITA ++  GE   + G GNGP+AA+ +AL  
Sbjct: 485 AETYLDATTPLEQVAMRVDAAVTERDQAKITAELRFQGESVTVSGTGNGPIAAYANALEQ 544

Query: 540 LGINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSIT 585
           LGI+V V++Y++H                 ++G+ VWGVGIA SIT
Sbjct: 545 LGIDVEVQEYTQHARTAGDDAEAAAYIFADVNGQKVWGVGIAGSIT 590


>tr|B1VIR4|B1VIR4_CORU7 Tax_Id=504474 SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium urealyticum]
          Length = 613

 Score =  794 bits (2050), Expect = 0.0
 Identities = 388/594 (65%), Positives = 452/594 (76%), Gaps = 15/594 (2%)

Query: 7   SSDAF-STGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKV 65
           ++D+F S    I  P+G     QPAWN QR S MP  RY  F +EV+ I+LPDRTWPDKV
Sbjct: 3   NTDSFISAPAQIQTPNGEIPADQPAWNKQRNSQMPNRRYLPFFEEVDHITLPDRTWPDKV 62

Query: 66  IETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 125
           I+ AP WCAVDLRDGNQALIDPMSP+RKRRMFD+LV MGYKEIEVGFPSASQTD+DFVRE
Sbjct: 63  IDRAPQWCAVDLRDGNQALIDPMSPERKRRMFDMLVEMGYKEIEVGFPSASQTDYDFVRE 122

Query: 126 IIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXX 185
           IIE+N IPDDVTIQVL Q+R  LI RTFEAC GAKNVIVHFYNSTS LQRRVVFR     
Sbjct: 123 IIEENKIPDDVTIQVLVQAREHLIRRTFEACAGAKNVIVHFYNSTSELQRRVVFRKDKEG 182

Query: 186 XXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPV 245
                     L+ E A+ YPDTNWRWEYSPES+TGTE+ YAKEVCDAV E++  TP+NP+
Sbjct: 183 IKKLATDAAHLIKEIAQDYPDTNWRWEYSPESFTGTEIEYAKEVCDAVVEVIDPTPENPI 242

Query: 246 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 305
           I+NLP+TVEM TPNVYADSIEWMHRNL RRDS+ILSLHPHNDRG GVAAAELGY AGADR
Sbjct: 243 IINLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGEGVAAAELGYMAGADR 302

Query: 306 IEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 365
           IEGCLFGNGERTGNVCLVTLGLNM ++GVDPQIDFS+ID+IRRTVEYCNQL V ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLGLNMLTQGVDPQIDFSDIDQIRRTVEYCNQLRVPERHPYG 362

Query: 366 GDLVYTAFSGSHQDAINKGL--------------DQMKVXXXXXXXXXXXILWQVPYLPI 411
           G+LV+TAFSGSHQDAINKGL              D               + W+VPYLPI
Sbjct: 363 GELVFTAFSGSHQDAINKGLAAMAERDAAEDTPEDPASADSETLTEAVRNVTWEVPYLPI 422

Query: 412 DPKDVGRTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVS 471
           DPKD+GR+YEAVIRVNSQSGKGGVAYIMK DH L LPR +Q+EFS ++Q +TD EGGEV+
Sbjct: 423 DPKDIGRSYEAVIRVNSQSGKGGVAYIMKTDHNLDLPRPMQVEFSGIVQAVTDAEGGEVN 482

Query: 472 PKEMWDAFSEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLA 531
           PK MWD F+ EYL    P++ +   VD  + +G    +T+ ++ NGE + + G GNGP+A
Sbjct: 483 PKAMWDIFATEYLDRTAPVDVISTTVDGGQNEGEESAVTSQIEFNGEAKTLKGRGNGPIA 542

Query: 532 AFCDALGALGINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSIT 585
           A+CDAL +LG++V V++Y++H                 ++G+ VWGVGIA SIT
Sbjct: 543 AYCDALESLGVDVEVQEYNQHARTSGDDAEAAAYVLAEVNGQRVWGVGIAGSIT 596


>tr|Q6NJX5|Q6NJX5_CORDI Tax_Id=1717 (leuA)SubName:
           Full=2-isopropylmalate synthase;
           EC=2.3.3.13;[Corynebacterium diphtheriae]
          Length = 605

 Score =  792 bits (2046), Expect = 0.0
 Identities = 397/587 (67%), Positives = 446/587 (75%), Gaps = 8/587 (1%)

Query: 7   SSDAF-STGRTITPPSGAPHPGQPAWNTQRGSSMPVSRYRSFADEVEKISLPDRTWPDKV 65
           S D F S    I  P G   PGQ  WNTQR SSM V+RY+ F  EVE I LPDRTWP K 
Sbjct: 3   SPDTFISAPAAIVTPRGDKAPGQAPWNTQRNSSMAVNRYQPFHVEVENIDLPDRTWPQKR 62

Query: 66  IETAPMWCAVDLRDGNQALIDPMSPQRKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVRE 125
           I  AP WCAVDLRDGNQALIDPMSP+RKRRMF+LLV MGYKEIEVGFPSASQTDFDFVRE
Sbjct: 63  ITKAPQWCAVDLRDGNQALIDPMSPERKRRMFNLLVNMGYKEIEVGFPSASQTDFDFVRE 122

Query: 126 IIEDNAIPDDVTIQVLTQSRPELITRTFEACRGAKNVIVHFYNSTSILQRRVVFRXXXXX 185
           IIE+N IP+DVTIQVL Q+R  LI RTFEAC GAKNVIVHFYNSTSILQR VVFR     
Sbjct: 123 IIENNMIPNDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRDVVFRKDKAA 182

Query: 186 XXXXXXXXXELVLEEAKKYPDTNWRWEYSPESYTGTELSYAKEVCDAVTEILGATPDNPV 245
                    EL+   A  YPDTNWRWEYSPESYTGTEL+YAKEV DAV  ++  TP+NP+
Sbjct: 183 IKKLATDAAELIKSIAVDYPDTNWRWEYSPESYTGTELTYAKEVVDAVVAVMDPTPENPI 242

Query: 246 ILNLPATVEMATPNVYADSIEWMHRNLARRDSVILSLHPHNDRGTGVAAAELGYQAGADR 305
           I+NLP+TVEM TPNVYAD IEWMHRNL RRDS+ILSLHPHNDRGTGVAAAELGY AGADR
Sbjct: 243 IINLPSTVEMITPNVYADGIEWMHRNLNRRDSIILSLHPHNDRGTGVAAAELGYLAGADR 302

Query: 306 IEGCLFGNGERTGNVCLVTLGLNMFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYG 365
           IEGCLFGNGERTGNVCLVTLGLNMF++GVDPQIDFS+ID+IRRTVEYCNQL V ERHPYG
Sbjct: 303 IEGCLFGNGERTGNVCLVTLGLNMFTQGVDPQIDFSDIDQIRRTVEYCNQLRVPERHPYG 362

Query: 366 GDLVYTAFSGSHQDAINKGLDQM-------KVXXXXXXXXXXXILWQVPYLPIDPKDVGR 418
           GDLV+TAFSGSHQDA+NKGLD M                      W+VPYLPIDPKDVGR
Sbjct: 363 GDLVFTAFSGSHQDAVNKGLDAMASRVHPGATHTEVSWDELRGETWEVPYLPIDPKDVGR 422

Query: 419 TYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQVIQQITDGEGGEVSPKEMWDA 478
            YEAVIRVNSQSGKGGVAYIMK DHGL LPR +Q+EFS ++Q++TD EGGEV+ K MWD 
Sbjct: 423 NYEAVIRVNSQSGKGGVAYIMKTDHGLALPRPMQVEFSSIVQEVTDAEGGEVNSKNMWDI 482

Query: 479 FSEEYLAPITPLERMRQKVDAAEEDGGTDKITAVVKVNGEEREIVGAGNGPLAAFCDALG 538
           F+ EYL   +P+E++   V+AAE +    +I A + VNG E  I G GNGP+AA+ +AL 
Sbjct: 483 FAREYLDSTSPVEQVSMSVNAAETENDEARIHARLIVNGSETTIEGHGNGPIAAYANALE 542

Query: 539 ALGINVNVRDYSEHXXXXXXXXXXXXXXXXXIDGKTVWGVGIATSIT 585
           +LGI+V V++Y +H                 ++GK  WGVGIA SIT
Sbjct: 543 SLGIDVEVQEYEQHARTAGDDAEAAAYILAEVNGKKFWGVGIAGSIT 589


  Database: Amellifera_nr
    Posted date:  Jul 23, 2010  5:10 AM
  Number of letters in database: 4,236,830,644
  Number of sequences in database:  12,507,864
  
Lambda     K      H
   0.317    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 12507864
Number of Hits to DB: 4,817,964,789
Number of extensions: 206765038
Number of successful extensions: 483192
Number of sequences better than 10.0: 3304
Number of HSP's gapped: 479222
Number of HSP's successfully gapped: 3381
Length of query: 602
Length of database: 4,236,830,644
Length adjustment: 144
Effective length of query: 458
Effective length of database: 2,435,698,228
Effective search space: 1115549788424
Effective search space used: 1115549788424
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 84 (37.0 bits)