BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_0353 (468 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HLS1|B2HLS1_MYCMM Tax_Id=216594 SubName: Full=Conserved hyp... 695 0.0 tr|P96820|P96820_MYCTU Tax_Id=1773 SubName: Full=PROBABLE CONSER... 605 e-171 tr|C6DR08|C6DR08_MYCTK Tax_Id=478434 SubName: Full=Conserved mem... 605 e-171 tr|A5TYL8|A5TYL8_MYCTA Tax_Id=419947 SubName: Full=Chloride chan... 605 e-171 tr|Q7DAE3|Q7DAE3_MYCTU Tax_Id=1773 SubName: Full=Chloride channe... 605 e-171 tr|A5WIJ8|A5WIJ8_MYCTF Tax_Id=336982 SubName: Full=Conserved tra... 605 e-171 tr|A2VN71|A2VN71_MYCTU Tax_Id=348776 SubName: Full=Putative unch... 605 e-171 tr|Q7U2R5|Q7U2R5_MYCBO Tax_Id=1765 SubName: Full=PROBABLE CONSER... 603 e-170 tr|C1AJG8|C1AJG8_MYCBT Tax_Id=561275 SubName: Full=Putative tran... 603 e-170 tr|A1KEW3|A1KEW3_MYCBP Tax_Id=410289 SubName: Full=Probable cons... 603 e-170 tr|A4KNG7|A4KNG7_MYCTU Tax_Id=395095 SubName: Full=Conserved tra... 603 e-170 tr|A0R690|A0R690_MYCS2 Tax_Id=246196 SubName: Full=Chloride chan... 461 e-128 tr|C1AYL9|C1AYL9_RHOOB Tax_Id=632772 SubName: Full=Putative ClC ... 377 e-102 tr|Q0S454|Q0S454_RHOSR Tax_Id=101510 SubName: Full=Chloride chan... 371 e-101 tr|C7LZ19|C7LZ19_ACIFD Tax_Id=525909 SubName: Full=Chloride chan... 293 4e-77 tr|Q6A5K7|Q6A5K7_PROAC Tax_Id=1747 SubName: Full=Putative chlori... 251 2e-64 tr|C9R8B5|C9R8B5_AMMDK Tax_Id=429009 SubName: Full=Cl-channel vo... 234 1e-59 tr|Q6KZW1|Q6KZW1_PICTO Tax_Id=82076 SubName: Full=Chloride chann... 224 2e-56 tr|A8MA93|A8MA93_CALMQ Tax_Id=397948 SubName: Full=Chloride chan... 222 9e-56 tr|Q97CK8|Q97CK8_THEVO Tax_Id=50339 SubName: Full=Putative uncha... 209 6e-52 tr|Q4J864|Q4J864_SULAC Tax_Id=2285 SubName: Full=Voltage-gated c... 205 9e-51 tr|Q9HI81|Q9HI81_THEAC Tax_Id=2303 SubName: Full=Chloride channe... 204 2e-50 tr|A3MWE4|A3MWE4_PYRCJ Tax_Id=410359 SubName: Full=Cl-channel, v... 200 4e-49 tr|B4U809|B4U809_HYDS0 Tax_Id=380749 SubName: Full=Chloride chan... 198 1e-48 tr|Q97U23|Q97U23_SULSO Tax_Id=2287 SubName: Full=Putative unchar... 195 9e-48 tr|D0KR15|D0KR15_SULS9 Tax_Id=555311 SubName: Full=Cl-channel vo... 195 1e-47 tr|Q96XV7|Q96XV7_SULTO Tax_Id=111955 SubName: Full=Putative unch... 194 2e-47 tr|C3N9G2|C3N9G2_SULIY Tax_Id=439386 SubName: Full=Chloride chan... 191 1e-46 tr|C3N0U3|C3N0U3_SULIA Tax_Id=427318 SubName: Full=Chloride chan... 191 1e-46 tr|C4KJX0|C4KJX0_SULIK Tax_Id=426118 SubName: Full=Chloride chan... 191 2e-46 tr|C3MRV4|C3MRV4_SULIM Tax_Id=427317 SubName: Full=Chloride chan... 190 4e-46 tr|C3NM12|C3NM12_SULIN Tax_Id=419942 SubName: Full=Chloride chan... 189 5e-46 tr|C3MK03|C3MK03_SULIL Tax_Id=429572 SubName: Full=Chloride chan... 189 7e-46 tr|Q1JX75|Q1JX75_DESAC Tax_Id=281689 SubName: Full=Cl-channel, v... 186 7e-45 tr|C1SIP9|C1SIP9_9BACT Tax_Id=522772 SubName: Full=Chloride chan... 182 6e-44 tr|A4YDN2|A4YDN2_METS5 Tax_Id=399549 SubName: Full=Cl-channel, v... 182 8e-44 tr|D1A4U4|D1A4U4_THECU Tax_Id=471852 SubName: Full=Chloride chan... 172 6e-41 tr|A2SSD4|A2SSD4_METLZ Tax_Id=410358 SubName: Full=Cl-channel, v... 172 1e-40 tr|Q3A443|Q3A443_PELCD Tax_Id=338963 SubName: Full=Chloride chan... 166 5e-39 tr|C0QEH3|C0QEH3_DESAH Tax_Id=177437 (eriC2)SubName: Full=EriC2;... 166 6e-39 tr|A3CW01|A3CW01_METMJ Tax_Id=368407 SubName: Full=Cl-channel, v... 166 8e-39 tr|A7I6T5|A7I6T5_METB6 Tax_Id=456442 SubName: Full=Cl-channel, v... 165 1e-38 tr|D1JC90|D1JC90_9ARCH Tax_Id=115547 SubName: Full=Probable volt... 163 4e-38 tr|D1JBB3|D1JBB3_9ARCH Tax_Id=115547 SubName: Full=Putative chlo... 163 4e-38 tr|C0QQU7|C0QQU7_PERMH Tax_Id=123214 SubName: Full=Chloride chan... 161 1e-37 tr|B8FFG6|B8FFG6_DESAA Tax_Id=439235 SubName: Full=Chloride chan... 161 2e-37 tr|C1F0W1|C1F0W1_ACIC5 Tax_Id=240015 SubName: Full=Chloride tran... 160 4e-37 tr|C8X5N8|C8X5N8_DESRD Tax_Id=485915 SubName: Full=Cl-channel vo... 159 1e-36 tr|A0LKT1|A0LKT1_SYNFM Tax_Id=335543 SubName: Full=Cl-channel, v... 159 1e-36 tr|Q15SM8|Q15SM8_PSEA6 Tax_Id=342610 SubName: Full=Cl-channel, v... 158 1e-36 >tr|B2HLS1|B2HLS1_MYCMM Tax_Id=216594 SubName: Full=Conserved hypothetical transmembrane protein;[Mycobacterium marinum] Length = 468 Score = 695 bits (1794), Expect = 0.0 Identities = 368/468 (78%), Positives = 369/468 (78%) Query: 1 VSPAAAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYH 60 +SPAAAGGRFGASIRNAGYLQKWF VVFYLALKYTGEFLLGYLADYH Sbjct: 1 MSPAAAGGRFGASIRNAGYLQKWFLLGITIGGIAGLGAVVFYLALKYTGEFLLGYLADYH 60 Query: 61 IPTPVGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNP 120 IPTPVGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNP Sbjct: 61 IPTPVGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNP 120 Query: 121 RSIRSRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXX 180 RSIRSRAVLVKMVASALTI REGPTAQISAGFCSFLTRRLGLSDEDGRTAV Sbjct: 121 RSIRSRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSFLTRRLGLSDEDGRTAVALG 180 Query: 181 XXXXXXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYI 240 VLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYI Sbjct: 181 IGAGIGAIFAAPLGGAVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYI 240 Query: 241 DAEYRFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXX 300 DAEYRFEKAWPLLWF YLYARVFHASVGLAHRLPGGPVIKPA Sbjct: 241 DAEYRFEKAWPLLWFVVIGVVAAAIGYLYARVFHASVGLAHRLPGGPVIKPAVGGLLVGL 300 Query: 301 XXXXIPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXX 360 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKI Sbjct: 301 MGLLIPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKILATSLSIGTGGSGGLFGPG 360 Query: 361 XXXXAFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSF 420 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSF Sbjct: 361 IVIGAFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSF 420 Query: 421 SVVPGAILAVGIASLLMSRTNVTIYEAQRLNXXXXXXXXXXXXXDRGN 468 SVVPGAILAVGIASLLMSRTNVTIYEAQRLN DRGN Sbjct: 421 SVVPGAILAVGIASLLMSRTNVTIYEAQRLNRETAEAERAARAADRGN 468 >tr|P96820|P96820_MYCTU Tax_Id=1773 SubName: Full=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;[Mycobacterium tuberculosis] Length = 492 Score = 605 bits (1561), Expect = e-171 Identities = 314/447 (70%), Positives = 335/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGRFG SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|C6DR08|C6DR08_MYCTK Tax_Id=478434 SubName: Full=Conserved membrane protein;[Mycobacterium tuberculosis] Length = 492 Score = 605 bits (1561), Expect = e-171 Identities = 314/447 (70%), Positives = 335/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGRFG SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|A5TYL8|A5TYL8_MYCTA Tax_Id=419947 SubName: Full=Chloride channel;[Mycobacterium tuberculosis] Length = 492 Score = 605 bits (1561), Expect = e-171 Identities = 314/447 (70%), Positives = 335/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGRFG SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|Q7DAE3|Q7DAE3_MYCTU Tax_Id=1773 SubName: Full=Chloride channel;[Mycobacterium tuberculosis] Length = 492 Score = 605 bits (1561), Expect = e-171 Identities = 314/447 (70%), Positives = 335/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGRFG SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGTRAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFVAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|A5WIJ8|A5WIJ8_MYCTF Tax_Id=336982 SubName: Full=Conserved transmembrane protein;[Mycobacterium tuberculosis] Length = 492 Score = 605 bits (1561), Expect = e-171 Identities = 314/447 (70%), Positives = 335/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGRFG SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|A2VN71|A2VN71_MYCTU Tax_Id=348776 SubName: Full=Putative uncharacterized protein;[Mycobacterium tuberculosis C] Length = 492 Score = 605 bits (1561), Expect = e-171 Identities = 314/447 (70%), Positives = 335/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGRFG SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|Q7U2R5|Q7U2R5_MYCBO Tax_Id=1765 SubName: Full=PROBABLE CONSERVED TRANSMEMBRANE PROTEIN;[Mycobacterium bovis] Length = 492 Score = 603 bits (1555), Expect = e-170 Identities = 313/447 (70%), Positives = 334/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGR G SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRLGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|C1AJG8|C1AJG8_MYCBT Tax_Id=561275 SubName: Full=Putative transmembrane protein;[Mycobacterium bovis] Length = 492 Score = 603 bits (1555), Expect = e-170 Identities = 313/447 (70%), Positives = 334/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGR G SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRLGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|A1KEW3|A1KEW3_MYCBP Tax_Id=410289 SubName: Full=Probable conserved transmembrane protein;[Mycobacterium bovis] Length = 492 Score = 603 bits (1555), Expect = e-170 Identities = 313/447 (70%), Positives = 334/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGR G SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRLGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAGFCS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|A4KNG7|A4KNG7_MYCTU Tax_Id=395095 SubName: Full=Conserved transmembrane protein;[Mycobacterium tuberculosis str. Haarlem] Length = 492 Score = 603 bits (1555), Expect = e-170 Identities = 313/447 (70%), Positives = 334/447 (74%) Query: 5 AAGGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTP 64 AAGGRFG SIR+AGYL+KWF VVFYLALKYT EFLLGYLADY IPTP Sbjct: 29 AAGGRFGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTP 88 Query: 65 VGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 VGEGG GS+GF RPWAIPL+TTGGA+LSA IVA+ APEATGHGTDEAIE+VH +PR+IR Sbjct: 89 VGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIR 148 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 RAVLVKMVASALTI REGPTAQISAG CS LTRRL LS+EDGRTAV Sbjct: 149 GRAVLVKMVASALTIGSGGSGGREGPTAQISAGLCSLLTRRLNLSNEDGRTAVALGIGAG 208 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 L ASI YRDDFDYR+LLPGFI SGTAYAVLGAF+GFDPLFGYIDAEY Sbjct: 209 IGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEY 268 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 RFEKAWPLLWF YLYARVFHASV + RLPGGPV+KPA Sbjct: 269 RFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLP 328 Query: 305 IPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 IPQILSSGYGWAQLAADR L++IPLWI+IVLP+AKI Sbjct: 329 IPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIG 388 Query: 365 AFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVP 424 AFVGAAIWRLGELT LPGVP PGIFVVVAMM CFGSVSRAPLAVMIMVAEMTGSFSVVP Sbjct: 389 AFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVP 448 Query: 425 GAILAVGIASLLMSRTNVTIYEAQRLN 451 GAI+AVGIA+LL+SRTNVTIYE QRLN Sbjct: 449 GAIIAVGIAALLLSRTNVTIYETQRLN 475 >tr|A0R690|A0R690_MYCS2 Tax_Id=246196 SubName: Full=Chloride channel;[Mycobacterium smegmatis] Length = 458 Score = 461 bits (1187), Expect = e-128 Identities = 240/442 (54%), Positives = 288/442 (65%) Query: 8 GRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGE 67 G G +RN+GY++KW VVFYLAL G LLGYL Y IP P G+ Sbjct: 9 GGLGNFVRNSGYVRKWLILGIAIGVIAGLGAVVFYLALDGAGRVLLGYLGGYDIPKPSGD 68 Query: 68 GGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRA 127 GG+ GS GF RPWAIPLI+ GGAL+SA+ VA+FAPEA GHGTD+AIEAVHT+PR IR RA Sbjct: 69 GGNPGSPGFDRPWAIPLISCGGALVSAWFVAKFAPEAEGHGTDDAIEAVHTDPRKIRVRA 128 Query: 128 VLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXX 187 ++VK +ASALTI REGP A ISAGF S LTR L LSDEDGR AV Sbjct: 129 IVVKTIASALTIGSGGSGGREGPAAHISAGFGSLLTRWLNLSDEDGRLAVSLGIGAGIGA 188 Query: 188 XXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFE 247 VLAASI YRDDFDYR+L+PGFITS +AYAVLG+ +GFDPLFG++ +YRF Sbjct: 189 IFGAPLGGAVLAASIVYRDDFDYRALIPGFITSASAYAVLGSILGFDPLFGFLVGDYRFG 248 Query: 248 KAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQ 307 +A L WF +LYARVF+ +V + LPGG ++KPA IPQ Sbjct: 249 QALDLAWFVVLGVIAGGVGWLYARVFYGTVAVTKMLPGGKIVKPALGGLAVGLMALAIPQ 308 Query: 308 ILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFV 367 +L+SGYGWA+ AA LM IPLWI++VLPVAKI AFV Sbjct: 309 VLASGYGWAEKAAATETLMNIPLWIVLVLPVAKIVATSLSIGTGGSGGIFGPGVVIGAFV 368 Query: 368 GAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAI 427 GAA+WRLG+ LPG+PD+P IFVVV MM CFG V+ APLAVMIMV EMT SF+V+P A+ Sbjct: 369 GAALWRLGDALALPGIPDSPAIFVVVGMMACFGCVAHAPLAVMIMVCEMTSSFAVIPCAM 428 Query: 428 LAVGIASLLMSRTNVTIYEAQR 449 + VG+A L +SR++V IY AQR Sbjct: 429 VGVGVACLTISRSDVAIYRAQR 450 >tr|C1AYL9|C1AYL9_RHOOB Tax_Id=632772 SubName: Full=Putative ClC chloride channel;[Rhodococcus opacus] Length = 470 Score = 377 bits (967), Expect = e-102 Identities = 203/445 (45%), Positives = 256/445 (57%), Gaps = 1/445 (0%) Query: 7 GGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVG 66 G GA IR+AGY +KW VVFY+AL + L+ + YH PT G Sbjct: 15 GASAGAWIRSAGYTRKWLVLGVVIGIVAGLGAVVFYVALSEATQLLIVDIGGYHPPTAAG 74 Query: 67 EGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSR 126 +GG+ GS F RPWAIPL+ G L+S +V APEA GHGTD AIEAVH +PR IR R Sbjct: 75 DGGAGGSREFTRPWAIPLVVCLGGLVSGILVFTLAPEAEGHGTDAAIEAVHRDPRMIRVR 134 Query: 127 AVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXX 186 VLVK+VASA+TI REGPTAQISAGF S L RRL LS DGR AV Sbjct: 135 VVLVKLVASAITIGSGGSGGREGPTAQISAGFGSLLARRLNLSPRDGRIAVAIGIGSGIG 194 Query: 187 XXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRF 246 VL +I Y++DFD+ L+P +TS +Y V G+F+GF PLFGY +Y F Sbjct: 195 AIFGAPLGGAVLCCTIPYKEDFDFEVLVPALVTSIVSYTVFGSFLGFGPLFGYAAQDYVF 254 Query: 247 EKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIP 306 + L+WF LY+ F+ +V L HRLPG ++KPA +P Sbjct: 255 DTPAQLVWFALIGVLGGLIGLLYSGTFYTAVDLTHRLPGSRIVKPAVGGLLVGLMALVLP 314 Query: 307 QILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAF 366 ++L SGYGW Q + R+ L AIPLW++++LP AKI AF Sbjct: 315 EVLGSGYGWIQQSMARDDLAAIPLWVVLLLPFAKILATSLSIGSGGSGGIFGPGMVIGAF 374 Query: 367 VGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGA 426 GAA+WRL E PGVPD P FV+V MM CFGS++RAPLAVM+MVAEMTGS V+ Sbjct: 375 TGAAVWRLLEPIA-PGVPDNPAPFVIVGMMACFGSIARAPLAVMLMVAEMTGSIGVLVPG 433 Query: 427 ILAVGIASLLMSRTNVTIYEAQRLN 451 ++AVG++ L++ R+ TIY AQ N Sbjct: 434 MIAVGLSYLIVRRSGKTIYRAQLEN 458 >tr|Q0S454|Q0S454_RHOSR Tax_Id=101510 SubName: Full=Chloride channel transporter;[Rhodococcus sp.] Length = 464 Score = 371 bits (953), Expect = e-101 Identities = 202/445 (45%), Positives = 254/445 (57%), Gaps = 1/445 (0%) Query: 7 GGRFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVG 66 G G IR +GY +KW VVFY+AL+ + L+ + Y PT G Sbjct: 12 GTSAGKWIRTSGYTRKWLVLGVVIGIVAGLGAVVFYVALREATQLLIVGIGGYTPPTAAG 71 Query: 67 EGGSHGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSR 126 +GG+ GS F RPWAIPL+ G L+S IV APEA GHGTD AI+AVH +PR IR R Sbjct: 72 DGGAVGSREFTRPWAIPLVVCLGGLVSGIIVFTLAPEAEGHGTDAAIDAVHRDPRMIRVR 131 Query: 127 AVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXX 186 VLVK+VASA+TI REGPTAQISAGF S L RRL LS DGR AV Sbjct: 132 VVLVKLVASAITIGSGGSGGREGPTAQISAGFGSLLARRLDLSPRDGRIAVAIGIGSGIG 191 Query: 187 XXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRF 246 VL +I Y++DFD+ L+P +TS +Y V G+F+GF PLFGY +Y F Sbjct: 192 AIFGAPLGGAVLCCTIPYKEDFDFEVLVPALVTSIVSYTVFGSFLGFGPLFGYAAQDYVF 251 Query: 247 EKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIP 306 + L+WF LY+ F+ +V L HRLPG ++KPA +P Sbjct: 252 DTPVQLVWFALIGVLGGLIGLLYSGTFYTAVDLTHRLPGSRIVKPAVGGLLVGLMALVLP 311 Query: 307 QILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAF 366 ++L SGYGW Q + R L AIPLW++++LP AKI AF Sbjct: 312 EVLGSGYGWIQQSMARGDLTAIPLWVVLLLPFAKILATSLSIGSGGSGGIFGPGMVIGAF 371 Query: 367 VGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGA 426 GAA+WRL E PGVPD P FV+V MM CFGS++RAPLAVM+MVAEMTGS V+ Sbjct: 372 TGAAVWRLLEPIA-PGVPDNPAPFVIVGMMACFGSIARAPLAVMLMVAEMTGSVGVLVPG 430 Query: 427 ILAVGIASLLMSRTNVTIYEAQRLN 451 ++AVG+A L++ R+ TIY AQR N Sbjct: 431 MIAVGLAYLIVRRSGKTIYRAQREN 455 >tr|C7LZ19|C7LZ19_ACIFD Tax_Id=525909 SubName: Full=Chloride channel core; Flags: Precursor;[Acidimicrobium ferrooxidans] Length = 453 Score = 293 bits (749), Expect = 4e-77 Identities = 173/411 (42%), Positives = 224/411 (54%), Gaps = 5/411 (1%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVA 98 V+FY AL + L LA Y +PTP GEG + GS + RPWAIPL GA+ + +V Sbjct: 36 VIFYAALTFATHEFLAVLAGYQVPTPAGEGNAPGSLHYARPWAIPLSVVLGAIGAGMLVF 95 Query: 99 RFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPTAQISAGF 158 APEA GHGTD AI+AV +PR IR RAV+VK++ASALTI REGPTAQISAGF Sbjct: 96 TLAPEAEGHGTDAAIDAVLHDPRGIRLRAVVVKIIASALTIGSGGSGGREGPTAQISAGF 155 Query: 159 CSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFI 218 S L R L L EDGR AV VLAA I YRDDF+Y +LLPG + Sbjct: 156 GSLLARVLDLGTEDGRVAVSVGIGSGIGAIFGAPLGGAVLAAEIVYRDDFEYEALLPGLL 215 Query: 219 TSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVG 278 S A A+ A GF PLF + + L+WF LYAR F+ +V Sbjct: 216 ASLIASAIFDAVYGFRPLFA-VAGHFELTTPLTLVWFAIVGVVAGAIGLLYARSFYGTVR 274 Query: 279 LAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAADRNALMAIPLWIIIVLPV 338 LA RLP +PA +P++L +GYGW Q + ++ PL +I+VLP+ Sbjct: 275 LARRLPIPRHFRPAIGGLLVGLLALWLPEVLGTGYGWVQKGLS-DQMLHTPLLVIVVLPI 333 Query: 339 AKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWR-LGELTGLPGVPDAPGIFVVVAMMT 397 A+I AF G A+WR L L +P + FVVV MM Sbjct: 334 ARIVATSLSIGTGGSGGVFGPGMVIGAFTGLAVWRILAPL--VPAIGHDASAFVVVGMMA 391 Query: 398 CFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMSRTNVTIYEAQ 448 FG +SRAP+AVM+MVAEMTG+ +++ A++AV IA L++ + +IY +Q Sbjct: 392 MFGGISRAPIAVMLMVAEMTGTIALLGPAMIAVAIAWLIVKAVDDSIYRSQ 442 >tr|Q6A5K7|Q6A5K7_PROAC Tax_Id=1747 SubName: Full=Putative chloride channel;[Propionibacterium acnes] Length = 575 Score = 251 bits (640), Expect = 2e-64 Identities = 146/424 (34%), Positives = 212/424 (50%), Gaps = 4/424 (0%) Query: 20 LQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVRP 79 L +W ++F+ LK +LL L Y P +GEGG + RP Sbjct: 37 LNRWLLMGTVIGIVSGVGAIIFFFCLKTGTHWLLETLGGYTPPGTLGEGGGVAGTRLTRP 96 Query: 80 WAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTI 139 WAIPLI GGAL+S +V AP A GHGTD AI AVH +P +++ + VK++AS+L I Sbjct: 97 WAIPLIVAGGALVSGTLVYFVAPTAKGHGTDNAIHAVHHDPTALKGKVAAVKIIASSLVI 156 Query: 140 XXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLA 199 REGPTAQISA S L ++L ++ D R AV +L Sbjct: 157 GSGGSGGREGPTAQISATVISSLCKKLKIATPDARIAVSAATASGIGAIFRAPLGGALLG 216 Query: 200 ASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXX 259 A + YRDD + +++P ++S A+ V G+ GF+P+FG + +F + L+WF Sbjct: 217 AELLYRDDMESDAIMPSLVSSIVAFVVFGSVYGFEPIFGSLSG-VQFSQPLQLIWFVLLG 275 Query: 260 XXXXXXXYLYARVFHASVGLAHRLPGGP-VIKPAXXXXXXXXXXXXIPQILSSGYGWAQL 318 LY VF++ L RL P + PA IP L +GYG Q Sbjct: 276 LTAGLMGKLYVEVFYSGTTLFDRLDKVPGWLVPAIGGLGVGLLGLLIPAALGTGYGSVQQ 335 Query: 319 AADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELT 378 N L+ +PL +++ +P AKI GAA+WRL L Sbjct: 336 EMFANNLVRMPLLMVLAIPFAKILSTTLSIGSGGSGGVFGPGMVIGGATGAALWRL--LE 393 Query: 379 GLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMS 438 GLPG+P +P FV+V M+ CFG+V+ APL V++MV EMTG+ S++ ++AV +A ++ Sbjct: 394 GLPGIPSSPMSFVIVGMIACFGAVAHAPLGVLLMVGEMTGNLSMLAPGMIAVAVAGRVVG 453 Query: 439 RTNV 442 T++ Sbjct: 454 DTSI 457 >tr|C9R8B5|C9R8B5_AMMDK Tax_Id=429009 SubName: Full=Cl-channel voltage-gated family protein;[Ammonifex degensii] Length = 598 Score = 234 bits (598), Expect = 1e-59 Identities = 153/431 (35%), Positives = 216/431 (50%), Gaps = 10/431 (2%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVR 78 YL KW +VFY A+ L A +H P +GEG + R Sbjct: 15 YLAKWLLIAGSIGAVAGVGAIVFYEAIHLFTYLFLNLGAGFHPPEALGEGQPVVTE-ISR 73 Query: 79 PWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALT 138 W IP++TT G LLS IV +FAPEA GHGTD AI+A H IR+R LVK++ASA+T Sbjct: 74 RWMIPVVTTLGGLLSGLIVFKFAPEAEGHGTDAAIDAFHHKEGIIRARVPLVKIIASAIT 133 Query: 139 IXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVL 198 I REGPTAQI+AGF S + + L L+ D A+ +L Sbjct: 134 IGSGGSAGREGPTAQIAAGFGSIMGQLLKLNTRDRCIALATGIGAGIGAIFKAPLGGALL 193 Query: 199 AASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXX 258 + I Y + F+ ++L+P FI S Y + ++ G+ P+FG++ F+ LL++ Sbjct: 194 STEILYLEGFEVQALVPSFIASLIGYTIFASYAGYMPVFGWMSQNIAFDPV-TLLYYALL 252 Query: 259 XXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQL 318 LY + F+A+ ++ +KPA +PQ+L GYGW QL Sbjct: 253 GVLCGLIGILYTKTFYATRNFFKKINLPKWLKPAAGGLLVGIMGLFLPQVLGMGYGWLQL 312 Query: 319 AADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELT 378 L PL I+++L AKI VG A+W+L L Sbjct: 313 GMLNKPL---PLDIVVLLIFAKILATSLTIGSGGSGGVFAPGLFIGGMVGTALWQL--LH 367 Query: 379 GLPG-VPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLM 437 G+ G +P +P F+VV MM FG+V+ APLAVM MV EMTGS++++ A++AVGIA +L+ Sbjct: 368 GMVGHLPASPQPFIVVGMMALFGAVAHAPLAVMFMVGEMTGSYTMLVPAMIAVGIAYVLV 427 Query: 438 SRTNVTIYEAQ 448 N TIYE+Q Sbjct: 428 G--NNTIYESQ 436 >tr|Q6KZW1|Q6KZW1_PICTO Tax_Id=82076 SubName: Full=Chloride channel protein;[Picrophilus torridus] Length = 590 Score = 224 bits (570), Expect = 2e-56 Identities = 146/448 (32%), Positives = 212/448 (47%), Gaps = 11/448 (2%) Query: 9 RFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEG 68 R + + Y +KWF +FY ++++ L + ++P P+GE Sbjct: 3 RISFKLSSLPYFEKWFIMGLIIGIISGLGATIFYFSIRFFEYIFLARIVGTNLPRPLGEN 62 Query: 69 GSHGSSGF-VRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRA 127 GS + +R + IP++ GA +S+FIV RFAPEA GHGTD AI + H N IR R Sbjct: 63 GSLIYHFYALRFYLIPVVLIAGAAISSFIVQRFAPEAEGHGTDSAIRSFHYNYGKIRRRI 122 Query: 128 VLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXX 187 +VK +ASA+TI REGPTAQI+AG SF+ LGL+ D R AV Sbjct: 123 PVVKTIASAITIGSGGSAGREGPTAQIAAGLGSFIADLLGLTPRDRRIAVAVGIGSGIGT 182 Query: 188 XXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFE 247 VL A I YR D + L P + + Y++ + +GF+P+FGY + Sbjct: 183 IFKAPIGGAVLGAEILYRRDMETEVLFPSIVAASVGYSIFASIVGFEPIFGYYLLPF--- 239 Query: 248 KAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQ 307 L ++ Y R F+ + RL P KP P+ Sbjct: 240 NPLRLPFYATLGLITGLFAIFYVRFFYGTRDFFKRLNLSPYYKPIIGAAFTGIIALFFPE 299 Query: 308 ILSSGYGWAQLAA----DRNALMAIPLWIIIV-LPVAKIXXXXXXXXXXXXXXXXXXXXX 362 +LS+GYGW QL + +PL I +V LP K+ Sbjct: 300 VLSTGYGWVQLLEYGRFNEFVYYGMPLVIFLVFLPFMKVFATSFTVASGGSGGVFAPGIF 359 Query: 363 XXAFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSV 422 A +GA + L L G P + FV++ M++ FG+ +APL+V++MV EMTGS + Sbjct: 360 IGASLGALLGYLVHL-GFPYIAPNIAPFVIIGMLSFFGAAGKAPLSVILMVVEMTGSLQL 418 Query: 423 VPGAILAVGIASLLMSRTNVTIYEAQRL 450 +PGA+LAV I S ++S T +IYE+Q L Sbjct: 419 LPGAMLAVAI-SYIVSGTKYSIYESQVL 445 >tr|A8MA93|A8MA93_CALMQ Tax_Id=397948 SubName: Full=Chloride channel core;[Caldivirga maquilingensis] Length = 586 Score = 222 bits (565), Expect = 9e-56 Identities = 150/447 (33%), Positives = 201/447 (44%), Gaps = 21/447 (4%) Query: 13 SIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGS-- 70 +I Y KWF + FY LK+ + L + P P+GEGGS Sbjct: 2 NISELPYYVKWFILGIVIGVVAGLSALAFYFTLKFMEYLFMVRLIAFKPPLPIGEGGSLN 61 Query: 71 ---HGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRA 127 H R W IP+ T G LLS IV +APEA GHGTD AI A H IR R Sbjct: 62 YVLHAG----RLWLIPVSTALGGLLSGLIVYTWAPEAEGHGTDAAINAFHRLQGRIRRRI 117 Query: 128 VLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXX 187 +K++ASA+TI REGPTAQ+SAG SF+ LGLS ED R AV Sbjct: 118 PPIKLIASAITIGSGGSAGREGPTAQLSAGIGSFIADLLGLSAEDRRIAVAVGIGAGIGS 177 Query: 188 XXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFE 247 +LAA + Y+ D + L P + S Y++ + +GF P+FGY + Sbjct: 178 IFKAPMGGAILAAEVLYKRDMETEVLFPALVASVVGYSIFSSIVGFTPIFGYYTGVF--- 234 Query: 248 KAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQ 307 L + LY + F+ R +KP +P+ Sbjct: 235 NPLRLPLYAVLGIVDGLVAVLYVKTFYFIHDSFKRWRISNYVKPVIGGLATGLIGLLVPE 294 Query: 308 ILSSGYGWAQLAADRNA------LMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXX 361 IL +GYGW LA N ++ PL I+I+LP KI Sbjct: 295 ILGTGYGWVNLAEFNNVNAFASPVLIPPLMILILLPFLKIIATSFTVGSGGSGGVFAPGI 354 Query: 362 XXXAFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFS 421 AF G W L PG+ P FV+V+M+ FG+ ++APLAVM MV EMTGS+ Sbjct: 355 VIGAFTGFDAWLLFHYL-TPGLTPNPAPFVIVSMLALFGASAKAPLAVMFMVIEMTGSYQ 413 Query: 422 VVPGAILAVGIASLLMSRTNVTIYEAQ 448 ++P A++AV IA ++ + TIY AQ Sbjct: 414 LLPAAMIAVAIAYIVSG--DYTIYRAQ 438 >tr|Q97CK8|Q97CK8_THEVO Tax_Id=50339 SubName: Full=Putative uncharacterized protein TVG0097142;[Thermoplasma volcanium] Length = 592 Score = 209 bits (532), Expect = 6e-52 Identities = 133/431 (30%), Positives = 201/431 (46%), Gaps = 12/431 (2%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVR 78 Y +KWF + FY A+K L ++ IP PVGEGGS + +VR Sbjct: 15 YFEKWFIMGLIIGVISGLGALAFYFAIKLFEYLFLTHMVGATIPHPVGEGGSLAFTYYVR 74 Query: 79 P-WAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASAL 137 + IP+ T G L S IV FAPEA GHGTD AI A H IR R +VK +ASA+ Sbjct: 75 RFYLIPVSTALGGLFSGLIVYTFAPEAEGHGTDAAIRAFHNEQGKIRRRIPVVKTIASAI 134 Query: 138 TIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXV 197 TI REGPTAQISAG S + GLSD D R AV + Sbjct: 135 TIGSGGSAGREGPTAQISAGLGSLIADLFGLSDADRRIAVAVGIGSGIGTIFKTPIGGTM 194 Query: 198 LAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXX 257 L A I Y+ D + +++ P + + Y++ + +GF+P+FGY A ++ + + ++ Sbjct: 195 LGAEILYKRDLETQAIYPSLVANAVGYSIFASVVGFEPIFGYYTASFQVIR---IPYYMV 251 Query: 258 XXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQ 317 Y + F+ +V +L KP P+I+++GYGW Sbjct: 252 LGVISGLFAIFYVKSFYGTVAFFKKLKISNYYKPIIGGGLTGIIALFFPEIMATGYGWVN 311 Query: 318 LAADRNALMAIP------LWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAI 371 L ++ L IP L ++I+LP K+ A +G + Sbjct: 312 LLMNQK-LGEIPTFGIPLLLVLILLPFIKVIATSFTVGSGGSGGVYAPGIFIGAALGTVV 370 Query: 372 WRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVG 431 +G P + FV++ M++ FGS + PL+V++MV EMTGS ++PGA++A Sbjct: 371 -AIGFHYLTPSIVPTITPFVIIGMISFFGSAGKVPLSVILMVVEMTGSLQLLPGAMIATF 429 Query: 432 IASLLMSRTNV 442 IA ++ + ++ Sbjct: 430 IAYIISGKYSI 440 >tr|Q4J864|Q4J864_SULAC Tax_Id=2285 SubName: Full=Voltage-gated chloride channel;[Sulfolobus acidocaldarius] Length = 587 Score = 205 bits (522), Expect = 9e-51 Identities = 148/438 (33%), Positives = 195/438 (44%), Gaps = 16/438 (3%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHG---SSG 75 Y +KWF FYL L L L IP P+GEGGS SSG Sbjct: 8 YFEKWFILGVILGIIAGLAATAFYLLLHVFEGLFLYSLVSISIPKPLGEGGSLNFVFSSG 67 Query: 76 FVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVAS 135 R + IPL G LLS IV FAPEA GHGTD AI+A H I+ V VK++AS Sbjct: 68 --RYYLIPLSVALGGLLSGLIVYTFAPEAEGHGTDAAIKAYHYYQGKIKWIVVPVKIIAS 125 Query: 136 ALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXX 195 A+TI REGPTAQ SAG S + L LS ED R AV Sbjct: 126 AITIGSGGSAGREGPTAQFSAGVGSIIADLLKLSPEDRRKAVAVGIGAGIGTIFKTPIGG 185 Query: 196 XVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWF 255 +LAA I Y+ D + + P I S Y + G+ GF+P+FGY + L + Sbjct: 186 AILAAEILYKRDIEPEVIYPTLIASAIGYTIFGSIFGFEPVFGYYTGSF---NPLRLPMY 242 Query: 256 XXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGW 315 LY + F+ +L IKP +P+++ GYGW Sbjct: 243 AILGVISGLLAILYVKTFYGINSFFKKLKTKNYIKPLIGGLVSGAIALLVPEVMGVGYGW 302 Query: 316 AQLAADRNALM----AIPLWIIIVL-PVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAA 370 L +P ++I+ L P KI AF+GA Sbjct: 303 INLVEYEKFSSFYSPILPFFVILALIPFLKILATSFSIGSGASGGVFAPGLFIGAFMGAD 362 Query: 371 IWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAV 430 + + L VPD FV++ MM+ F + +APL+V+IMV EMTGS ++PGA++AV Sbjct: 363 VGLVFHLLFPTIVPDI-SPFVIIGMMSFFSAAGKAPLSVIIMVTEMTGSLQLLPGAMIAV 421 Query: 431 GIASLLMSRTNVTIYEAQ 448 I+ L+ N TIY+AQ Sbjct: 422 AISYLISG--NYTIYQAQ 437 >tr|Q9HI81|Q9HI81_THEAC Tax_Id=2303 SubName: Full=Chloride channel (CLC-3) related protein;[Thermoplasma acidophilum] Length = 589 Score = 204 bits (519), Expect = 2e-50 Identities = 138/446 (30%), Positives = 204/446 (45%), Gaps = 22/446 (4%) Query: 9 RFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEG 68 RF + + Y +KWF + FY A++ L + +P P+GEG Sbjct: 2 RFRFHLSSLPYFEKWFIMGIIIGIISGLGALAFYYAIRLFEYLFLTRMVGIALPRPLGEG 61 Query: 69 GSHGSSGFVRP-WAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRA 127 GS VR + IP+ G L S IV FAPEA GHGTD AI A H N IR R Sbjct: 62 GSLVYLYSVRYFYLIPVSVALGGLFSGLIVYTFAPEAEGHGTDAAIRAFHNNQGKIRRRI 121 Query: 128 VLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXX 187 +VK +ASA+TI REGPTAQISAG S + LGLSD D R AV Sbjct: 122 PVVKTIASAITIGSGGSAGREGPTAQISAGLGSMVADLLGLSDSDRRIAVAVGIGSGIGT 181 Query: 188 XXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFE 247 +L A I Y+ D + +++ P + + Y++ + +GF+P+FGY + E Sbjct: 182 IFKTPIGGTMLGAEILYKRDLETQAIYPSLVANAIGYSIFASVVGFEPIFGYYTGSFNVE 241 Query: 248 KAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQ 307 + + ++ Y R F+ V + R+ KP P+ Sbjct: 242 R---IPYYAILGVISGLFAIFYVRFFYFMVSVFKRMRISNYYKPVIGGAVTGLIALAFPE 298 Query: 308 ILSSGYGWAQLAADRN----ALMAIPLWIIIV-LPVAKIXXXXXXXXXXXXXXXXXXXXX 362 I+S+GYGW L + IP+ II++ LP K+ Sbjct: 299 IMSTGYGWVDLLMFQKFQYFPTFGIPILIILIALPFVKV----FATSFTVGSGGSGGVYA 354 Query: 363 XXAFVGAAIWRLGELTGLPGVPDAPGI------FVVVAMMTCFGSVSRAPLAVMIMVAEM 416 F+GA+ LG + GL P + FV+V M++ FG+ + PL+V++MV EM Sbjct: 355 PGIFIGAS---LGAVAGLAFHYATPSLVPIITPFVIVGMISFFGAAGKVPLSVILMVVEM 411 Query: 417 TGSFSVVPGAILAVGIASLLMSRTNV 442 TGS ++P A++AV I+ L+ + ++ Sbjct: 412 TGSLQLLPAAMIAVFISYLVSGKYSI 437 >tr|A3MWE4|A3MWE4_PYRCJ Tax_Id=410359 SubName: Full=Cl-channel, voltage-gated family protein; Flags: Precursor;[Pyrobaculum calidifontis] Length = 582 Score = 200 bits (508), Expect = 4e-49 Identities = 139/442 (31%), Positives = 196/442 (44%), Gaps = 12/442 (2%) Query: 13 SIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGG-SH 71 SI Y KW + F AL+ +F L + +P PVGEGG + Sbjct: 2 SISTLPYFVKWIIVGTLIGVVAAVAALTFIYALELCQKFFLEQIVGVELPRPVGEGGLGN 61 Query: 72 GSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVK 131 + R W +P+ T G LLS +V APEA GHGTD AI A H IR R VK Sbjct: 62 YTLTSERLWLLPVATGLGGLLSGLLVYGLAPEAEGHGTDAAINAYHRLRGRIRRRVPFVK 121 Query: 132 MVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXX 191 +VASA+TI REGPTAQ+SAG S + L L+D+D R Sbjct: 122 LVASAVTIGSGGSAGREGPTAQLSAGLGSIIADILRLNDDDRRIVTMVAAGAGIGTIFKA 181 Query: 192 XXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWP 251 + AA + Y+ D + L P + + YA+ GA GF P+FG + A + + Sbjct: 182 PIGGALFAAEVLYKRDVESEVLFPALVAAIVGYAIYGAITGFTPVFGEVPAHFDVRQ--- 238 Query: 252 LLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSS 311 L F Y+Y +VF+ P +KP PQIL Sbjct: 239 LPLFALLGLVSGAVAYVYVKVFYYFHDRFKSWHTSPYVKPLVGGLAVGALGIVAPQILGV 298 Query: 312 GYGWAQLAADRN-----ALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAF 366 GYGW L + + + + +I +LP+ KI AF Sbjct: 299 GYGWVSLLIQESPSAFYSPILPAVLLIALLPLLKILATSLTVGSGGSGGVFAPGLVIGAF 358 Query: 367 VGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGA 426 VG ++ + + T P + F+VV M++ FG+ S+APLA IMV EMTGS+ ++P A Sbjct: 359 VGYDMYLVFK-TLFPSLAPNAAPFIVVGMLSLFGAASKAPLATAIMVVEMTGSYDLLPAA 417 Query: 427 ILAVGIASLLMSRTNVTIYEAQ 448 I+AV +A L+ ++Y +Q Sbjct: 418 IIAVAVARLVSGED--SLYRSQ 437 >tr|B4U809|B4U809_HYDS0 Tax_Id=380749 SubName: Full=Chloride channel core;[Hydrogenobaculum sp.] Length = 462 Score = 198 bits (503), Expect = 1e-48 Identities = 136/450 (30%), Positives = 204/450 (45%), Gaps = 18/450 (4%) Query: 9 RFGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEG 68 + G+ I Y KWF + FY +LK + YHIP+P GE Sbjct: 7 KIGSFISRQDYFLKWFILGLINGVVSGLGALFFYYSLKLCEFIFFNKILHYHIPSPTGEE 66 Query: 69 GSH--GSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSR 126 ++ G V + +P++ G ++ FIV ++APEA GHGTD AI+A H IR R Sbjct: 67 PNNLIFKPGLV--YLLPIVIAFGGFIAGFIVFKWAPEAEGHGTDAAIDAYHNKKGFIRDR 124 Query: 127 AVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXX 186 + +K +ASA+TI REGPTA ISAG S+L R LGLS++D + Sbjct: 125 VIFIKSIASAITIGSGGSAGREGPTALISAGIGSWLARLLGLSEKDRERMLALGIGAGIG 184 Query: 187 XXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRF 246 +L A I Y+ D ++ PG + S Y++ G+ +GF P+FGY + Sbjct: 185 TIFKAPIGGAILGAEILYKSDLQADNIFPGLVASAVGYSIFGSIVGFVPVFGYYLQNF-- 242 Query: 247 EKAWPLLWFXXXXXXXXXXXYLYARVF-HASVGLAHRLPGGPVIKPAXXXXXXXXXXXXI 305 L + +YA+ F + L L +KP Sbjct: 243 -NPLRLPLYIILGIVCGIVGRIYAKTFYYFKDNLFKSLKTNIYLKPVIGMFLTGIIGMAF 301 Query: 306 PQILSSGYGWAQLAADRNALM----AIPLWI-IIVLPVAKIXXXXXXXXXXXXXXXXXXX 360 P++L +GYGW Q A D M IPL+I ++L KI Sbjct: 302 PEVLGTGYGWLQGAIDTKFSMFDTYGIPLFIFFVLLAFIKIIATSLTVGSGASGGVFAPG 361 Query: 361 XXXXAFVGAAIWRLGELTGLPGVPDAP--GIFVVVAMMTCFGSVSRAPLAVMIMVAEMTG 418 F+GA + + P + + G FV+V M+ FG+ +AP+AV +MV EMTG Sbjct: 362 LFIGGFLGAGLGIVYHQL-FPSLVNTSHIGGFVIVGMLALFGAAGKAPVAVTLMVVEMTG 420 Query: 419 SFSVVPGAILAVGIASLLMSRTNVTIYEAQ 448 S+ ++P +LAV +A L+ + +IY++Q Sbjct: 421 SYQLLPACMLAVAVAYLISG--DYSIYKSQ 448 >tr|Q97U23|Q97U23_SULSO Tax_Id=2287 SubName: Full=Putative uncharacterized protein;[Sulfolobus solfataricus] Length = 595 Score = 195 bits (496), Expect = 9e-48 Identities = 146/452 (32%), Positives = 200/452 (44%), Gaps = 26/452 (5%) Query: 10 FGASIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGG 69 + ++ + Y +KWF FYL L + L +L P P+GEGG Sbjct: 12 YDMNLSSLPYFEKWFILGIVLGVVAGLAATTFYLLLHVFEDIFLFHLIGMSYPRPLGEGG 71 Query: 70 S-----HGSSGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIR 124 + H + + IP+ T G L+S IV FAPEA GHGTD AI+A H ++ Sbjct: 72 TLNFVFHPGNYLL----IPISTAIGGLISGLIVYTFAPEAEGHGTDAAIKAYHYFQGKVK 127 Query: 125 SRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXX 184 + VK++ASA+TI REGPTAQ SAG S + L LS ED R AV Sbjct: 128 WVVIPVKIIASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRAVAVGIGAG 187 Query: 185 XXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEY 244 +LAA I YR D + + P I S Y + G+ GF P+FGY + Sbjct: 188 IGTIFKTPIGGAILAAEILYRRDLEPEVIYPALIASAIGYTIFGSIFGFTPVFGYYTGTF 247 Query: 245 RFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXX 304 L + LY + F+ L +L +KPA Sbjct: 248 ---DPLRLPMYAVLGLVSGLVAILYPKTFYGINSLFKKLRITDHVKPAIGGLVTGVIALL 304 Query: 305 IPQILSSGYGWAQL-------AADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXX 357 P+IL +GYGW L A L AI L I++LP KI Sbjct: 305 APEILGTGYGWINLVEYEKFFALYSPVLPAIIL--IVILPFLKIIATSFSVGSGGSGGVF 362 Query: 358 XXXXXXXAFVGAAIWRLGELTGLPGVPD-APGIFVVVAMMTCFGSVSRAPLAVMIMVAEM 416 A++GA+I + VPD AP FV++ MM+ F + PL+V+IMV EM Sbjct: 363 APGLFIGAYIGASIGLMFHYLFPSVVPDIAP--FVIIGMMSFFAGAGKVPLSVLIMVTEM 420 Query: 417 TGSFSVVPGAILAVGIASLLMSRTNVTIYEAQ 448 T S ++PGA++AV I+ L+ N TIY +Q Sbjct: 421 TSSLQLLPGAMVAVAISYLVSG--NSTIYISQ 450 >tr|D0KR15|D0KR15_SULS9 Tax_Id=555311 SubName: Full=Cl-channel voltage-gated family protein;[Sulfolobus solfataricus] Length = 582 Score = 195 bits (495), Expect = 1e-47 Identities = 146/443 (32%), Positives = 196/443 (44%), Gaps = 26/443 (5%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGS-----HGS 73 Y +KWF FYL L + L +L P P+GEGG+ H Sbjct: 8 YFEKWFILGIVLGVVAGLAATTFYLLLHVFEDIFLFHLIGMSYPRPLGEGGTLNFVFHPG 67 Query: 74 SGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMV 133 + + IP+ T G L+S IV FAPEA GHGTD AI+A H ++ + VK++ Sbjct: 68 NYLL----IPISTAIGGLISGLIVYTFAPEAEGHGTDAAIKAYHYFQGKVKWVVIPVKII 123 Query: 134 ASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXX 193 ASA+TI REGPTAQ SAG S + L LS ED R AV Sbjct: 124 ASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRAVAVGIGAGIGTIFKTPI 183 Query: 194 XXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLL 253 +LAA I YR D + + P I S Y + G+ GF P+FGY + L Sbjct: 184 GGAILAAEILYRRDLEPEVIYPALIASAIGYTIFGSIFGFTPVFGYYTGTF---DPLRLP 240 Query: 254 WFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGY 313 + LY + F+ L +L +KPA P+IL +GY Sbjct: 241 MYAVLGLVSGLVAILYPKTFYGINSLFKKLRITDHVKPAIGGLVTGVIALLAPEILGTGY 300 Query: 314 GWAQL-------AADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAF 366 GW L A L AI L I++LP KI A+ Sbjct: 301 GWINLVEYEKFFALYSPVLPAIIL--IVILPFLKIIATSFSVGSGGSGGVFAPGLFIGAY 358 Query: 367 VGAAIWRLGELTGLPGVPD-APGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPG 425 +GA+I + VPD AP FV++ MM+ F + PL+V+IMV EMT S ++PG Sbjct: 359 IGASIGLMFHYLFPSVVPDIAP--FVIIGMMSFFAGAGKVPLSVLIMVTEMTSSLQLLPG 416 Query: 426 AILAVGIASLLMSRTNVTIYEAQ 448 A++AV I+ L+ N TIY +Q Sbjct: 417 AMVAVAISYLVSG--NSTIYISQ 437 >tr|Q96XV7|Q96XV7_SULTO Tax_Id=111955 SubName: Full=Putative uncharacterized protein ST2411;[Sulfolobus tokodaii] Length = 584 Score = 194 bits (494), Expect = 2e-47 Identities = 139/436 (31%), Positives = 195/436 (44%), Gaps = 12/436 (2%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFV- 77 Y +KW FYL L + + +L P P+GEGGS + + Sbjct: 8 YYEKWAILGVILGIVAGLAATTFYLLLHLAEDLFIFHLIGMSYPRPLGEGGSLNFTFYPG 67 Query: 78 RPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASAL 137 R + IPL T G L+S IV FAPEA GHGTD AI+A H +R + VK++ASA+ Sbjct: 68 RYYLIPLSTAIGGLISGLIVYTFAPEAEGHGTDAAIKAYHYLQGKVRWVVIPVKIIASAI 127 Query: 138 TIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXV 197 TI REGPTAQ SAG S + L LS +D R AV + Sbjct: 128 TIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPQDRRIAVAVGIGAGIGTIFKTPIGGAI 187 Query: 198 LAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXX 257 LAA I Y+ DF+ L P I S Y + G+ GF P+FGY Y L + Sbjct: 188 LAAEILYKRDFEPEVLYPAIIASAIGYTIFGSIFGFTPVFGYYTGTY---NPLRLPMYAV 244 Query: 258 XXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQ 317 +Y + F+ +L IKP P+IL++GYGW Sbjct: 245 LGVVAGLLAIIYVKTFYGIHSFFKKLRIPNYIKPLIGGALTGLIALLAPEILATGYGWIN 304 Query: 318 LAADR--NALMA--IPLWIII-VLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIW 372 L NA + IP+ I+I +LP+ KI A++GA++ Sbjct: 305 LVEYERFNAFYSPLIPVLILIFLLPILKIVATSFSVGSGGSGGVFAPGLFIGAYIGASVG 364 Query: 373 RLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGI 432 L P + FV++ MM F + + P++V+IMV EMT S ++PGA++A + Sbjct: 365 LLFHYF-FPNIVPNIAPFVIIGMMAFFAAAGKVPVSVIIMVTEMTSSLQLLPGAMIASAL 423 Query: 433 ASLLMSRTNVTIYEAQ 448 A L+ + TIY +Q Sbjct: 424 AYLVSG--DYTIYVSQ 437 >tr|C3N9G2|C3N9G2_SULIY Tax_Id=439386 SubName: Full=Chloride channel core;[Sulfolobus islandicus] Length = 582 Score = 191 bits (486), Expect = 1e-46 Identities = 137/440 (31%), Positives = 193/440 (43%), Gaps = 20/440 (4%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGS-----HGS 73 Y +KWF FYL L + L + P P+GEGG+ H Sbjct: 8 YFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPG 67 Query: 74 SGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMV 133 + + IP+ T G L+S IV FAPEA GHGTD AI+A H +R + VK++ Sbjct: 68 NYLL----IPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRWVVIPVKII 123 Query: 134 ASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXX 193 ASA+TI REGPTAQ SAG S + L LS ED R A+ Sbjct: 124 ASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGIGTIFKTPI 183 Query: 194 XXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLL 253 +LAA I YR D + + P + S Y + G+ GF P+FGY + L Sbjct: 184 GGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF---DPLRLP 240 Query: 254 WFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGY 313 + LY + F+ L +L +KPA P+IL +GY Sbjct: 241 MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGY 300 Query: 314 GWAQLAA-DRNALMAIPL----WIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVG 368 GW L ++ + PL ++++LP KI A++G Sbjct: 301 GWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIG 360 Query: 369 AAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAIL 428 A+I L P + FV++ MM+ F + PL+V+IMV EMT S ++PGA++ Sbjct: 361 ASIGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSLQLLPGAMI 419 Query: 429 AVGIASLLMSRTNVTIYEAQ 448 AV I+ L+ N TIY +Q Sbjct: 420 AVAISYLVSG--NNTIYISQ 437 >tr|C3N0U3|C3N0U3_SULIA Tax_Id=427318 SubName: Full=Chloride channel core;[Sulfolobus islandicus] Length = 582 Score = 191 bits (486), Expect = 1e-46 Identities = 137/440 (31%), Positives = 193/440 (43%), Gaps = 20/440 (4%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGS-----HGS 73 Y +KWF FYL L + L + P P+GEGG+ H Sbjct: 8 YFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPG 67 Query: 74 SGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMV 133 + + IP+ T G L+S IV FAPEA GHGTD AI+A H IR + VK++ Sbjct: 68 NYLL----IPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRWVVIPVKII 123 Query: 134 ASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXX 193 ASA+TI REGPTAQ SAG S + L LS ED R A+ Sbjct: 124 ASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGIGTIFKTPI 183 Query: 194 XXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLL 253 +LAA I YR D + + P + S Y + G+ GF P+FGY + L Sbjct: 184 GGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF---DPLRLP 240 Query: 254 WFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGY 313 + LY + F+ L +L +KPA P+IL +GY Sbjct: 241 MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGY 300 Query: 314 GWAQLAA-DRNALMAIPL----WIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVG 368 GW L ++ + PL ++++LP KI A++G Sbjct: 301 GWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIG 360 Query: 369 AAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAIL 428 A++ L P + FV++ MM+ F + PL+V+IMV EMT S ++PGA++ Sbjct: 361 ASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSLQLLPGAMI 419 Query: 429 AVGIASLLMSRTNVTIYEAQ 448 AV I+ L+ N TIY +Q Sbjct: 420 AVAISYLVSG--NNTIYISQ 437 >tr|C4KJX0|C4KJX0_SULIK Tax_Id=426118 SubName: Full=Chloride channel core; Flags: Precursor;[Sulfolobus islandicus] Length = 582 Score = 191 bits (485), Expect = 2e-46 Identities = 137/440 (31%), Positives = 193/440 (43%), Gaps = 20/440 (4%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGS-----HGS 73 Y +KWF FYL L + L + P P+GEGG+ H Sbjct: 8 YFKKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPG 67 Query: 74 SGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMV 133 + + IP+ T G L+S IV FAPEA GHGTD AI+A H IR + VK++ Sbjct: 68 NYLL----IPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRWVVIPVKII 123 Query: 134 ASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXX 193 ASA+TI REGPTAQ SAG S + L LS ED R A+ Sbjct: 124 ASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGIGTIFKTPI 183 Query: 194 XXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLL 253 +LAA I YR D + + P + S Y + G+ GF P+FGY + L Sbjct: 184 GGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF---DPLRLP 240 Query: 254 WFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGY 313 + LY + F+ L +L +KPA P+IL +GY Sbjct: 241 MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGY 300 Query: 314 GWAQLAA-DRNALMAIPL----WIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVG 368 GW L ++ + PL ++++LP KI A++G Sbjct: 301 GWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIG 360 Query: 369 AAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAIL 428 A++ L P + FV++ MM+ F + PL+V+IMV EMT S ++PGA++ Sbjct: 361 ASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSLQLLPGAMI 419 Query: 429 AVGIASLLMSRTNVTIYEAQ 448 AV I+ L+ N TIY +Q Sbjct: 420 AVAISYLVSG--NNTIYISQ 437 >tr|C3MRV4|C3MRV4_SULIM Tax_Id=427317 SubName: Full=Chloride channel core;[Sulfolobus islandicus] Length = 582 Score = 190 bits (482), Expect = 4e-46 Identities = 136/440 (30%), Positives = 192/440 (43%), Gaps = 20/440 (4%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGS-----HGS 73 Y +KWF FYL L + L + P P+GEGG+ H Sbjct: 8 YFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPG 67 Query: 74 SGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMV 133 + + IP+ T G L+S IV FAPEA GHGTD AI+A H IR + VK++ Sbjct: 68 NYLL----IPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKIRWVVIPVKII 123 Query: 134 ASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXX 193 ASA+TI REGPTAQ SAG S + L LS ED R A+ Sbjct: 124 ASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGIGTIFKTPI 183 Query: 194 XXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLL 253 +LAA I YR D + + P + S Y + G+ GF P+FGY + L Sbjct: 184 GGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF---DPLRLP 240 Query: 254 WFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGY 313 + LY + F+ L +L +KPA P+IL +GY Sbjct: 241 MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGY 300 Query: 314 GWAQLAA-DRNALMAIPL----WIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVG 368 GW L ++ + PL ++++LP KI A++G Sbjct: 301 GWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIG 360 Query: 369 AAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAIL 428 A++ L P + F ++ MM+ F + PL+V+IMV EMT S ++PGA++ Sbjct: 361 ASVGLLFHYL-FPNIVPTIAPFAIIGMMSFFAGAGKVPLSVLIMVTEMTSSLQLLPGAMI 419 Query: 429 AVGIASLLMSRTNVTIYEAQ 448 AV I+ L+ N TIY +Q Sbjct: 420 AVAISYLVSG--NNTIYISQ 437 >tr|C3NM12|C3NM12_SULIN Tax_Id=419942 SubName: Full=Chloride channel core;[Sulfolobus islandicus] Length = 582 Score = 189 bits (481), Expect = 5e-46 Identities = 135/440 (30%), Positives = 192/440 (43%), Gaps = 20/440 (4%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGS-----HGS 73 Y +KWF FYL L + L + P P+GEGG+ H Sbjct: 8 YFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPG 67 Query: 74 SGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMV 133 + + IP+ T G L+S IV FAPEA GHGTD AI+A H +R + VK++ Sbjct: 68 NYLL----IPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRWVVIPVKII 123 Query: 134 ASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXX 193 ASA+TI REGPTAQ SAG S + L LS ED R A+ Sbjct: 124 ASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGIGTIFKTPI 183 Query: 194 XXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLL 253 +LAA I YR D + + P + S Y + G+ GF P+FGY + L Sbjct: 184 GGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF---DPLRLP 240 Query: 254 WFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGY 313 + LY + F+ L +L +KPA P+IL +GY Sbjct: 241 MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAIGGLITGLIALLAPEILGTGY 300 Query: 314 GWAQLAA-DRNALMAIPL----WIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVG 368 GW L ++ + PL ++++LP KI A++G Sbjct: 301 GWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIG 360 Query: 369 AAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAIL 428 ++ L P + FV++ MM+ F + PL+V+IMV EMT S ++PGA++ Sbjct: 361 TSVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMTSSLQLLPGAMI 419 Query: 429 AVGIASLLMSRTNVTIYEAQ 448 AV I+ L+ N TIY +Q Sbjct: 420 AVAISYLVSG--NNTIYISQ 437 >tr|C3MK03|C3MK03_SULIL Tax_Id=429572 SubName: Full=Chloride channel core;[Sulfolobus islandicus] Length = 582 Score = 189 bits (480), Expect = 7e-46 Identities = 135/440 (30%), Positives = 192/440 (43%), Gaps = 20/440 (4%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGS-----HGS 73 Y +KWF FYL L + L + P P+GEGG+ H Sbjct: 8 YFEKWFILGIFLGVVAGLAATTFYLLLHLFEDIFLFHFIGMSYPRPLGEGGTLNFIFHPG 67 Query: 74 SGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMV 133 + + IP+ T G L+S IV FAPEA GHGTD AI+A H +R + VK++ Sbjct: 68 NYLL----IPISTAIGGLISGIIVYTFAPEAEGHGTDAAIKAYHYFQGKVRWVVIPVKII 123 Query: 134 ASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXX 193 ASA+TI REGPTAQ SAG S + L LS ED R A+ Sbjct: 124 ASAITIGSGGSAGREGPTAQFSAGVGSVIADLLHLSPEDRRRALAVGIGAGIGTIFKTPI 183 Query: 194 XXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLL 253 +LAA I YR D + + P + S Y + G+ GF P+FGY + L Sbjct: 184 GGAILAAEILYRRDLEPEVIYPALVASAIGYTIFGSIFGFTPVFGYYTGTF---DPLRLP 240 Query: 254 WFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGY 313 + LY + F+ L +L +KPA P+IL +GY Sbjct: 241 MYAVLGLVSGLMAILYPKTFYGVNSLFKKLRIPNHVKPAMGGLITGLIALLAPEILGTGY 300 Query: 314 GWAQLAA-DRNALMAIPL----WIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVG 368 GW L ++ + PL ++++LP KI A++G Sbjct: 301 GWINLVEYEKFFTLYSPLIPTIILLVILPFLKILGTSFSIGSGGSGGVFAPGLFIGAYIG 360 Query: 369 AAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAIL 428 A++ L P + FV++ MM+ F + PL+V+IMV EM S ++PGA++ Sbjct: 361 ASVGLLFHYL-FPNIVPTIAPFVIIGMMSFFAGAGKVPLSVLIMVTEMASSLQLLPGAMI 419 Query: 429 AVGIASLLMSRTNVTIYEAQ 448 AV I+ L+ N TIY +Q Sbjct: 420 AVAISYLVSG--NNTIYISQ 437 >tr|Q1JX75|Q1JX75_DESAC Tax_Id=281689 SubName: Full=Cl-channel, voltage gated;[Desulfuromonas acetoxidans DSM 684] Length = 606 Score = 186 bits (471), Expect = 7e-45 Identities = 134/420 (31%), Positives = 191/420 (45%), Gaps = 24/420 (5%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVRP---------WAIPLITTGG 89 + FY A +LLG A +H P EG H ++ +RP W + L+ G Sbjct: 41 LAFYFATNAVDHYLLGQTAHFHPPI---EG--HLATQEMRPVNTLQMDVSWLLYLMPMVG 95 Query: 90 ALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREG 149 L+S ++V R+APEA GHGTD A+EA H IR R LVK +AS TI REG Sbjct: 96 GLISGWLVYRYAPEAEGHGTDGALEAFHRRGGQIRGRVPLVKTLASIATIGTGGSAGREG 155 Query: 150 PTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRD-DF 208 P AQI AGF SF+ RLGL+ R + + A + YRD +F Sbjct: 156 PIAQIGAGFGSFVATRLGLTVSTRRILLLAGMAGGIGATFRSPLGGALFAVEVLYRDPEF 215 Query: 209 DYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXXXXXXXXXYL 268 ++ L+P I S TAY++ GA G++PL ++FE L+ + Sbjct: 216 EHEGLIPSIIASITAYSLFGAVTGWEPLLA--TPHFKFEHPGELILYCALGLVCALFGAG 273 Query: 269 YARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAADRNALMAI 328 Y +VF+ RL +KPA +PQ+L SGYGW Q A + Sbjct: 274 YVKVFYGLRDYFKRLRCPAWLKPALGGLLLGGLAMMVPQVLGSGYGWVQAA----LYGKM 329 Query: 329 PLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELTGLPGVPDAPG 388 L +++V+ VAKI A +G A L E P + P Sbjct: 330 ALSVMLVVAVAKIVATSLTISSGGSGGVFAPSLVIGAMLGGAFGALAEQL-FPALTQDPQ 388 Query: 389 IFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMSRTNVTIYEAQ 448 +V+V M F V+ AP+A +IMV+E+TG++ ++ +L +A + M R IYE Q Sbjct: 389 AYVLVGMAVFFAGVANAPIATLIMVSELTGNYGLLAPLMLVCVVAMIAMRRNG--IYEKQ 446 >tr|C1SIP9|C1SIP9_9BACT Tax_Id=522772 SubName: Full=Chloride channel protein EriC;[Denitrovibrio acetiphilus DSM 12809] Length = 595 Score = 182 bits (463), Expect = 6e-44 Identities = 128/432 (29%), Positives = 195/432 (45%), Gaps = 11/432 (2%) Query: 16 NAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGG--SHGS 73 N + +WF ++F+L L+ + F + YL + GE H + Sbjct: 8 NLPVIGRWFILGSIVGLVSGVGAIIFFLLLQGSSFFFMDYLMGIRVEETGGEHALFGHAA 67 Query: 74 SGFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMV 133 + F R W+I L+ G L+S F+V +FAPEA GHGTD AI+A+H SIR R ++K Sbjct: 68 TEF-RRWSILLVPALGGLISGFLVYKFAPEAEGHGTDAAIKAIHFKNGSIRWRVPIIKTF 126 Query: 134 ASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXX 193 ASA+TI REGP AQI AGF SFL L LS+ + R Sbjct: 127 ASAITIGTGGSGGREGPIAQIGAGFGSFLGTTLKLSERERRILTAAGMGAGVGAIFRSPL 186 Query: 194 XXXVLAASITY-RDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPL 252 + AA + Y D +Y +LLP ITS AY+V + G++PLF D + FE L Sbjct: 187 AGAIFAAEVLYASSDMEYEALLPSAITSIIAYSVFCSVYGWEPLFATPD--FAFENPVEL 244 Query: 253 LWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSG 312 + + +LY R F+ G+ ++ P IKP +PQ L+ Sbjct: 245 IGYSVLGFACAVFGWLYVRTFYGIHGIFKQMHISPYIKPVIGGFLTGCVGFFVPQALAGS 304 Query: 313 YGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIW 372 Y +L + + I +L AKI A VG + Sbjct: 305 YAQIELGMQGQ----LGIGFIFILIFAKILTTSFSIGSGGSAGIFGPSMVIGAAVGGFV- 359 Query: 373 RLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGI 432 L + +P + PG +V+V M F ++ PL+ +IMV+EMTG++ ++ ++ + Sbjct: 360 GLALNSFVPFIAPEPGAYVIVGMAGFFSGIANTPLSTIIMVSEMTGNYHLLVPSMWVSTL 419 Query: 433 ASLLMSRTNVTI 444 A LL+ +T + + Sbjct: 420 AFLLLRKTTMYV 431 >tr|A4YDN2|A4YDN2_METS5 Tax_Id=399549 SubName: Full=Cl-channel, voltage-gated family protein;[Metallosphaera sedula] Length = 588 Score = 182 bits (462), Expect = 8e-44 Identities = 134/440 (30%), Positives = 193/440 (43%), Gaps = 20/440 (4%) Query: 19 YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSS---- 74 Y +KW VFYL L + P P+GEGG+ + Sbjct: 10 YFEKWLILGILLGVVAGFASTVFYLLLHVFEYIFITRFVGMSYPHPLGEGGTLNFTFHPG 69 Query: 75 GFVRPWAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVA 134 F+ +P+ G L+S +V FAPEA GHGTD AI+A H +R + VK+ A Sbjct: 70 NFI---LVPVSLMIGGLISGLVVYTFAPEAEGHGTDAAIKAYHYLQGKVRWVVIPVKIFA 126 Query: 135 SALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXX 194 SA+TI REGPTAQ S+G S + L LS ED R A+ Sbjct: 127 SAVTIGSGGSAGREGPTAQFSSGVGSVIADLLKLSPEDRRRALAVGIGAGIGTIFKTPIG 186 Query: 195 XXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLW 254 +LA+ I Y+ D + + PG I S Y + G GF P+FGY + L Sbjct: 187 GALLASEILYKRDLEPELIYPGLIASSVGYTIFGIIFGFTPVFGYYTGTF---NPMRLPL 243 Query: 255 FXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYG 314 + LY + F+ GL RL +KP P+++ +GYG Sbjct: 244 YALLGVISGLLAILYVKSFYGISGLFKRLKLPNHVKPMIGGGLAGLLTLLFPEVMGTGYG 303 Query: 315 WAQLAA-DRNALMAIP----LWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGA 369 W LA +R + P L ++ +LP+ KI AF+GA Sbjct: 304 WINLAEFERFSSFYSPVLPVLLLLALLPLVKILATSLSIGSGGSGGVFAPGLFIGAFLGA 363 Query: 370 AIWRLGELTGLPGVPD-APGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAIL 428 + + VP+ AP FV++ MM+ F + + PL+V++MV EMT S ++PGA++ Sbjct: 364 DVGLIFHYLFPSLVPNIAP--FVIIGMMSFFAAAGKVPLSVIVMVTEMTSSLQLLPGAMI 421 Query: 429 AVGIASLLMSRTNVTIYEAQ 448 AV I+ L+ N TIY +Q Sbjct: 422 AVAISYLVSG--NYTIYRSQ 439 >tr|D1A4U4|D1A4U4_THECU Tax_Id=471852 SubName: Full=Chloride channel core;[Thermomonospora curvata DSM 43183] Length = 531 Score = 172 bits (437), Expect = 6e-41 Identities = 118/423 (27%), Positives = 180/423 (42%), Gaps = 16/423 (3%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVA 98 +VFY +++ + LG L +H T G+G + ++GF RPWA+PL+ GGA + F+ Sbjct: 46 IVFYALVEWATDVFLGLLVGHHPATVAGDGQARPATGFARPWALPLVAAGGAAAAVFLAG 105 Query: 99 RFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPTAQISAGF 158 R P+ TGHGTD I+A HT P + R + KM + + I EGP AQI Sbjct: 106 RVTPKTTGHGTDALIDAAHTEPERMGLRVLGRKMAGATVMIGSGGSGGTEGPIAQIGGTL 165 Query: 159 CSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFI 218 S + R G++ + RT + V+ A + YR + P + Sbjct: 166 GSTVARTAGVTRQLARTLLLTGAAAGIGAIFRAPMGGAVIGAELLYRRGLSVGCIPPALL 225 Query: 219 TSGTAYAVLGAFMGFDPLFG--YIDAEYRFEKAWPLL-WFXXXXXXXXXXXYLYARVFHA 275 SG AY + G P FG I + F PLL F LYA + ++ Sbjct: 226 GSGIAYGLFVLVHGPTPTFGALSITVPWAFPDLLPLLAAFAVLGVLCGLLGRLYACLLYS 285 Query: 276 SV---------GLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAADRNALM 326 + G R + PA P + +GYG AQ D+ ++ Sbjct: 286 VLRATRWAVGKGTGRRAAVLGYLFPALGGLLVGTLGLVFPGVAGTGYGTAQAVMDQRQVL 345 Query: 327 AIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELTGLPGVPDA 386 ++ W +++LPV K A G A+WR+ + GL G Sbjct: 346 SLAWWTLLLLPVMKAVATSLSIGTGGPGGVFGPGLVIGATAGGALWRVSDALGLEG--PG 403 Query: 387 PGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMSRTNVTIYE 446 P F +V M C G + APL V I+V E T S ++ +LAV +A ++ + ++Y Sbjct: 404 PAAFAIVGMAACLGPIIHAPLGVSILVFEATLSPGLLLPTLLAVMLARWIVG--DRSLYR 461 Query: 447 AQR 449 +QR Sbjct: 462 SQR 464 >tr|A2SSD4|A2SSD4_METLZ Tax_Id=410358 SubName: Full=Cl-channel, voltage-gated family protein;[Methanocorpusculum labreanum] Length = 457 Score = 172 bits (435), Expect = 1e-40 Identities = 139/433 (32%), Positives = 199/433 (45%), Gaps = 37/433 (8%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVRP---WAIPLITTGGALLSAF 95 ++F+ AL+Y ++G PTP G+ + G + + P W I I GGALLS Sbjct: 29 LLFFTALEYCINLIMGIFYGGAFPTP-GQSCT-GITCWTPPPIIWLILPIICGGALLSGL 86 Query: 96 IVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPTAQIS 155 IV +FAPEA GHGTD A++A H + + IR R VK VAS +TI REGPTAQI+ Sbjct: 87 IVYKFAPEAEGHGTDAALKAYHGDGK-IRWRVPFVKAVASLITISTGGSAGREGPTAQIA 145 Query: 156 AGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRDDFDYRSLLP 215 AGF + ++ LS + + A+ VLAA I Y D D L+P Sbjct: 146 AGFGAIISDVFQLSPRERKIAIATGIGAGIGTIFKAPLGGAVLAAEILYLRDVDADVLIP 205 Query: 216 GFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLL---WFXXXXXXXXXXXYLYARV 272 F+ S +Y++ G FMG+D +FG E W ++ +F +Y + Sbjct: 206 SFLASVISYSIFGFFMGYDAIFG------TTEMTWSVVQVPFFLALGPLCAFIGIMYIKS 259 Query: 273 FHASVGL---AHRLPGGPV-IKPAXXXXXXXXXXXXIPQI-----------LSSGYGWAQ 317 F+ + L R G P +KP I L SGYG+ Q Sbjct: 260 FYGTKTLFDKFFRTYGLPTYLKPVLGAFIIGIFVIVFAYISPDTLMVALGSLGSGYGFVQ 319 Query: 318 LAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGEL 377 LA +PL ++I+LP AK F G A + + Sbjct: 320 LA----LYNMLPLTVLILLPFAKTLTTSLTIGSGGSGGVFAPGISIGGFTGGAFGMILHI 375 Query: 378 TGLPGVP-DAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLL 436 +P IFV++ M+ FGS++ AP+AVMIMV EMTG F ++ A+ A+ +A L+ Sbjct: 376 LFPTIIPLTTVPIFVIIGMIALFGSIAHAPIAVMIMVLEMTGDFGILIPAMAALVLACLI 435 Query: 437 MSRTNVTIYEAQR 449 M + TI+ QR Sbjct: 436 MGKN--TIFREQR 446 >tr|Q3A443|Q3A443_PELCD Tax_Id=338963 SubName: Full=Chloride channel protein EriC;[Pelobacter carbinolicus] Length = 606 Score = 166 bits (421), Expect = 5e-39 Identities = 124/417 (29%), Positives = 185/417 (44%), Gaps = 19/417 (4%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVRP------WAIPLITTGGALL 92 + FY A E++L + H P G G + S G V W + +I G L+ Sbjct: 41 LAFYFATDTATEWILVHWGGLHTP---GHGNALQSGGVVNSLKMSHRWFLFVIPVLGGLV 97 Query: 93 SAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPTA 152 S ++V RFAPEA GHGTD AIEA H IR R +VK +AS TI REGP A Sbjct: 98 SGWLVFRFAPEAEGHGTDAAIEAFHQKKGLIRGRVPVVKAIASVATISTGGSAGREGPIA 157 Query: 153 QISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRD-DFDYR 211 QI AGF SFL RL LS D R + + A + Y+D +F++ Sbjct: 158 QIGAGFGSFLADRLKLSVSDRRVLLLAGMAGGVGATFRAPLGGALFAVEVLYQDPEFEHE 217 Query: 212 SLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXXXXXXXXXYLYAR 271 L+P I+S AY++ GA G+ PL +RFE L ++ Y + Sbjct: 218 GLIPCIISSIVAYSLFGAVTGWSPLLA--TPAFRFEHPVELGFYLLLGIACAILGTGYVK 275 Query: 272 VFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAADRNALMAIPLW 331 F+ + L +KPA +PQ+L SGYGW Q A + LW Sbjct: 276 TFYYARDRFVALNMPTWLKPALGGLILGVMAMFVPQVLGSGYGWVQAA----LYGKMALW 331 Query: 332 IIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELTGLPGVPDAPGIFV 391 ++++L + KI A +G + + P + P V Sbjct: 332 LMVLLGLGKIIATSLTISSGGSGGVFAPSLVIGAMLGGSFGAVVHAL-FPMLLAEPRTCV 390 Query: 392 VVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMSRTNVTIYEAQ 448 ++ M F V+ P+A +IMV+E+TG+++++ +L +A + R+ +IY+ Q Sbjct: 391 IIGMAGFFAGVANTPIATLIMVSELTGNYALLAPLMLVCVVAMVFFRRS--SIYQQQ 445 >tr|C0QEH3|C0QEH3_DESAH Tax_Id=177437 (eriC2)SubName: Full=EriC2;[Desulfobacterium autotrophicum] Length = 598 Score = 166 bits (420), Expect = 6e-39 Identities = 117/400 (29%), Positives = 178/400 (44%), Gaps = 9/400 (2%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFV-RPWAIPLITTGGALLSAFIV 97 V+F + F + ++A Y +P GE + V W + ++ G ++S ++V Sbjct: 39 VIFQYLCQLGLHFFMDFMAGYRPASPAGEHHLFPPTHSVFNRWILLILPAAGGIISGWLV 98 Query: 98 ARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPTAQISAG 157 FAPEA GHGTD AIEA H+ IRSR VK +ASA+T+ REGP AQI AG Sbjct: 99 YTFAPEAEGHGTDAAIEAYHSKGGFIRSRVPFVKTLASAITLTTGGSGGREGPIAQIGAG 158 Query: 158 FCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRD-DFDYRSLLPG 216 F SFL R+ LSD + R + + AA + YRD +F+ ++P Sbjct: 159 FGSFLATRMKLSDRERRIMMAAGVGAGVGSIFRAPLAGALFAAEVLYRDPEFESDVIIPA 218 Query: 217 FITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXXXXXXXXXYLYARVFHAS 276 I+S AY + G+ LF ++F+ L + Y + F+ Sbjct: 219 GISSVVAYCIFCLVFGWGSLFD--SPGFKFQNPLELGPYMVLALVLVVTGIFYVKTFYGI 276 Query: 277 VGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAADRNALMAIPLWIIIVL 336 G HRL +KPA +P L+ GYG+AQ A +A I++ L Sbjct: 277 AGFFHRLKIPNALKPAIGGLATGIIGFFLPYTLAFGYGYAQQAIFNELSIA----ILLAL 332 Query: 337 PVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELTGLPGVPDAPGIFVVVAMM 396 + KI +G + +L + +P V PG FV+V M Sbjct: 333 AIGKIFTTSFSIGSGGSGGVFGPSIVIGGAMGGVVGKLFHML-IPSVVTNPGTFVIVGMA 391 Query: 397 TCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLL 436 F +VS P++ +I V+EMT S+ ++ ++L + LL Sbjct: 392 GFFTAVSNTPISTIIFVSEMTNSYYLLLPSLLVCSLCYLL 431 >tr|A3CW01|A3CW01_METMJ Tax_Id=368407 SubName: Full=Cl-channel, voltage-gated family protein;[Methanoculleus marisnigri] Length = 754 Score = 166 bits (419), Expect = 8e-39 Identities = 127/389 (32%), Positives = 177/389 (45%), Gaps = 28/389 (7%) Query: 80 WAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTI 139 W I + G LLS +V FAPEA GHGTD AI+A H R +R R LVK V + LTI Sbjct: 197 WMILPVICFGGLLSGLLVYTFAPEAEGHGTDAAIKAFHGEGR-VRWRVPLVKAVTAVLTI 255 Query: 140 XXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLA 199 REGPTAQ+SAGF S LGLS + R A+ +LA Sbjct: 256 STGGSAGREGPTAQMSAGFGSIAADLLGLSARERRLAIATGVGAGIGTIFMAPLGGAILA 315 Query: 200 ASITYRDDFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXX 259 A I YR DF+ +++P F+ S YA+ G GF+P+FG + + + +F Sbjct: 316 AEILYRQDFETEAIVPAFLASVIGYAIFGLVEGFEPVFGPGVTSWNVSQ---IPFFILLG 372 Query: 260 XXXXXXXYLYARVFHAS----VGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQI------- 308 +Y F+ + + RL KP + + Sbjct: 373 VVSTAIGLIYINTFYGTNRIFKKVFSRLKIPNHFKPLAGAFLTGTFVLALAALSPEAAIV 432 Query: 309 ----LSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXX 364 L +GYG+AQLA +P+ +++ LP AKI Sbjct: 433 GLGSLGTGYGFAQLA----LYNMLPVGVLLFLPFAKILTTSLTIGSGGSGGVFAPGLVIG 488 Query: 365 AFVGAAIWRLGELTGLPGVPDAPG--IFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSV 422 G A L L LPG+ A +F +V M+ FG++S AP+AVMIMV EMTG FS+ Sbjct: 489 GATGGAFGSLLHL-ALPGIIPAESVPVFFIVGMIALFGAISHAPIAVMIMVVEMTGDFSL 547 Query: 423 VPGAILAVGIASLLMSRTNVTIYEAQRLN 451 + A+ AV +A +L+ ++ TI+ Q LN Sbjct: 548 LVPAMGAVSVAVILIGQS--TIFREQVLN 574 >tr|A7I6T5|A7I6T5_METB6 Tax_Id=456442 SubName: Full=Cl-channel, voltage-gated family protein;[Methanoregula boonei] Length = 612 Score = 165 bits (417), Expect = 1e-38 Identities = 131/429 (30%), Positives = 195/429 (45%), Gaps = 41/429 (9%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVRPWAIPL-------ITTGGAL 91 ++FY LK+ F +GY+ Y P EG S + + W+ P I G+L Sbjct: 31 LIFYEGLKWGIAFFMGYILQYVYPQ---EGQS---AAVISQWSDPHSLFLLIPILLFGSL 84 Query: 92 LSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPT 151 L+ ++ RFAPE GHGTD AI+A H R IR R ++K V + LTI REGP+ Sbjct: 85 LTGILITRFAPETEGHGTDAAIKAFHGTGR-IRKRVPILKAVTAILTISTGGSAGREGPS 143 Query: 152 AQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRDDFDYR 211 AQISAGF S + LGLS ++ R A+ VLAA + Y DF+ Sbjct: 144 AQISAGFGSVVADMLGLSPKERRIALTTGIGAGIGTIFKAPLGGAVLAAEVLYTRDFESD 203 Query: 212 SLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXXXXXXXXXYLYAR 271 +++P F+ S YA+ G F G+ P+F + + + +F LY Sbjct: 204 AIIPAFLASVIGYAIFGFFEGYAPIFSLGPISWTVVQ---IPFFLLLGILCAAFGLLYIF 260 Query: 272 VFHASVGL------AHRLPGGPVIKPAXXXXXXXXXXXXIPQI-----------LSSGYG 314 VF++S + LP P +KP + I L SGYG Sbjct: 261 VFYSSRDWFAAQFKRYNLP--PYLKPVSGALILGILVTALALISPEAETLGLSALGSGYG 318 Query: 315 WAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRL 374 + QL +PL +++++P KI A VGAA+ + Sbjct: 319 FDQLML----YSLLPLAVLLLMPFVKILATSLTLGSGGSGGVFGPGLTIGASVGAALGII 374 Query: 375 GELTGLPGVP-DAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIA 433 L VP + +F+VV M++ FG+V+ AP+AV+IMV EM GS +++ A+ AV ++ Sbjct: 375 LHLFFPVYVPLETIPVFIVVGMISLFGAVANAPIAVLIMVVEMVGSITILIPAMAAVAVS 434 Query: 434 SLLMSRTNV 442 LL + Sbjct: 435 HLLTGEKTI 443 >tr|D1JC90|D1JC90_9ARCH Tax_Id=115547 SubName: Full=Probable voltage gated chloride channel; SubName: Full=Putative voltage-gated chloride channel;[uncultured archaeon] Length = 612 Score = 163 bits (413), Expect = 4e-38 Identities = 128/450 (28%), Positives = 186/450 (41%), Gaps = 18/450 (4%) Query: 13 SIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHG 72 S + Y+Q+W FYL L+ +F LGYLA + P GE Sbjct: 8 STKERKYIQRWVLLSILIGIVAGFGAFAFYLLLQIMTDFFLGYLAGFQPTPPAGEQDVPY 67 Query: 73 SSGFVRP---WAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVL 129 S P W + L+ G L+ I+ FAPEA GHGTD I+A H IR R L Sbjct: 68 ISLPTAPFHLWVLALMPALGGLIVGLIIYSFAPEAEGHGTDAIIDAFHNKKGVIRKRVPL 127 Query: 130 VKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXX 189 +K +ASA+TI REGP AQI GF SFL +L L + + R + Sbjct: 128 IKAIASAITIGSGGSAGREGPIAQIGGGFGSFLGTKLKLGERETRMMMVCGAAAGIGAMF 187 Query: 190 XXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAF--MGFDPLFGYIDAEYRFE 247 + + Y+ DF+ SL+P ++S AYAV + +G+ P+F Y F Sbjct: 188 KAPLGSALFGTEVLYKRDFEMESLIPAIVSSVVAYAVFCSIPSIGWHPIFD--TPPYTFT 245 Query: 248 KAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXI-- 305 L++F Y +VF+A+ RL +KPA I Sbjct: 246 HPKELIFFAVLGIACTALGIFYIKVFYATRAFFKRLAIPNHLKPAIGGALVGIFVLVIGY 305 Query: 306 --PQ----ILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXX 359 PQ IL GYG Q A D + + ++I++ +AKI Sbjct: 306 VEPQALDGILGMGYGTVQTAIDMELPLPELIELMIIVAIAKIFTTSFTIGSGGSGGVFAP 365 Query: 360 XXXXXAFVGAAIWRLGELTGLPGVPDAP-GIFVVVAMMTCFGSVSRAPLAVMIMVAEMTG 418 A +G + + + FVVV M F ++ P+A ++M++EM G Sbjct: 366 SLVIGAMLGGLFGGVSHFFFPEIITETTMSAFVVVGMAAFFAGAAKVPIAAILMISEMAG 425 Query: 419 SFSVVPGAILAVGIASLLMSRTNVTIYEAQ 448 S+S++ +L +A L TIYE Q Sbjct: 426 SYSLLVPLMLTSVVAYALSG--GWTIYEKQ 453 >tr|D1JBB3|D1JBB3_9ARCH Tax_Id=115547 SubName: Full=Putative chloride channel;[uncultured archaeon] Length = 612 Score = 163 bits (413), Expect = 4e-38 Identities = 128/450 (28%), Positives = 186/450 (41%), Gaps = 18/450 (4%) Query: 13 SIRNAGYLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHG 72 S + Y+Q+W FYL L+ +F LGYLA + P GE Sbjct: 8 STKERKYIQRWVLLSILIGIVAGFGAFAFYLLLQIMTDFFLGYLAGFQPTPPAGEQDVPY 67 Query: 73 SSGFVRP---WAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVL 129 S P W + L+ G L+ I+ FAPEA GHGTD I+A H IR R L Sbjct: 68 ISLPTAPFHLWVLALMPALGGLIVGLIIYSFAPEAEGHGTDAIIDAFHNKKGVIRKRVPL 127 Query: 130 VKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXX 189 +K +ASA+TI REGP AQI GF SFL +L L + + R + Sbjct: 128 IKAIASAITIGSGGSAGREGPIAQIGGGFGSFLGTKLKLGERETRMMMVCGAAAGIGAMF 187 Query: 190 XXXXXXXVLAASITYRDDFDYRSLLPGFITSGTAYAVLGAF--MGFDPLFGYIDAEYRFE 247 + + Y+ DF+ SL+P ++S AYAV + +G+ P+F Y F Sbjct: 188 KAPLGSALFGTEVLYKRDFEMESLIPAIVSSVVAYAVFCSIPSIGWHPIFD--TPPYTFT 245 Query: 248 KAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXI-- 305 L++F Y +VF+A+ RL +KPA I Sbjct: 246 HPKELIFFAVLGIACTALGIFYIKVFYATRAFFKRLAIPNHLKPAIGGALVGIFVLVIGY 305 Query: 306 --PQ----ILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXX 359 PQ IL GYG Q A D + + ++I++ +AKI Sbjct: 306 VEPQALDGILGMGYGTVQTAIDMELPLPELIELMIIVAIAKIFTTSFTIGSGGSGGVFAP 365 Query: 360 XXXXXAFVGAAIWRLGELTGLPGVPDAP-GIFVVVAMMTCFGSVSRAPLAVMIMVAEMTG 418 A +G + + + FVVV M F ++ P+A ++M++EM G Sbjct: 366 SLVIGAMLGGLFGGVSHFFFPEIITETTMSAFVVVGMAAFFAGAAKVPIAAILMISEMAG 425 Query: 419 SFSVVPGAILAVGIASLLMSRTNVTIYEAQ 448 S+S++ +L +A L TIYE Q Sbjct: 426 SYSLLVPLMLTSVVAYALSG--GWTIYEKQ 453 >tr|C0QQU7|C0QQU7_PERMH Tax_Id=123214 SubName: Full=Chloride channel protein;[Persephonella marina] Length = 586 Score = 161 bits (408), Expect = 1e-37 Identities = 112/406 (27%), Positives = 183/406 (45%), Gaps = 4/406 (0%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSS-GFVRPWAIPLITTGGALLSAFIV 97 ++F A+K + +F LG + Y P+P GEGGSH S R + +P+ T G L+ +V Sbjct: 30 IIFLKAIKISSDFFLGGIVSYQPPSPFGEGGSHFFSFEMERAYLLPISTALGGLIVGILV 89 Query: 98 ARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPTAQISAG 157 F+PE+ G GTD AI A H + + + + ++K++ +A+TI +EGP A I AG Sbjct: 90 YLFSPESAGVGTDAAIRAFH-HRKYLGLKTSIMKLITAAVTIGSGGVSGKEGPIALIGAG 148 Query: 158 FCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRDDFDYRSLLPGF 217 SFL R LSD + A+ ++++ + Y+ DF+ +L+P F Sbjct: 149 IGSFLGRIFKLSDREKDIALAVGMGAGIAGVFKAPFAGAIISSEVFYKKDFETETLIPSF 208 Query: 218 ITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXXXXXXXXXYLYARVFHASV 277 I S A+ V+G+F+GF PLF ++ + L S Sbjct: 209 IASFIAFIVVGSFLGFSPLFHIELPQFNGLSVNDAAAYIFLGISTAMIARLMIFSLDKSR 268 Query: 278 GLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAADRNALMAIPLWIIIVLP 337 + + L PV KPA P + +GYGW Q+ N + PL I++ + Sbjct: 269 EIFNSLGIHPVFKPAVGGFFVGLMGMFTPVAIGTGYGWLQMIMSGNLVYLSPLLIVVSIF 328 Query: 338 VAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELTGLPGVPDAP-GIFVVVAMM 396 V I GA+++ L G VV M+ Sbjct: 329 VV-ILAFSFTLGSGGSGGVFGPSLVIGGLTGASVYYLLSAIGFQESSSFNITALTVVGMV 387 Query: 397 TCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMSRTNV 442 + F + ++APL+ +I+VAE+TG + ++ AI+AV I+ L ++ Sbjct: 388 STFAAAAKAPLSTLILVAEITGGYQLLVPAIIAVAISHFLSGEKSI 433 >tr|B8FFG6|B8FFG6_DESAA Tax_Id=439235 SubName: Full=Chloride channel core;[Desulfatibacillum alkenivorans] Length = 604 Score = 161 bits (407), Expect = 2e-37 Identities = 129/449 (28%), Positives = 185/449 (41%), Gaps = 12/449 (2%) Query: 7 GGRFGASIRNAG-YLQKWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPV 65 G FGA + G Y KW ++F+ + + L LA Y P Sbjct: 6 GKFFGARLDPKGAYAMKWVARFVAIGVVAGLGSILFHFLCEAGMRYFLDALAGYRPPAAA 65 Query: 66 GEGGSHGSSGFVRP--WAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSI 123 GE G P W + L+ G + S ++V FAPE+ GHGTD AI+A H I Sbjct: 66 GESHRMFEPGVKEPVRWMLLLLPAAGGIFSGWLVYTFAPESEGHGTDAAIDAYHNKGGFI 125 Query: 124 RSRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXX 183 R R ++K +ASA+T+ REGP AQI AGF SFL +L LSD + R + Sbjct: 126 RGRVPIIKTLASAITLTTGGSGGREGPIAQIGAGFGSFLATKLKLSDRERRIMLAAGMGA 185 Query: 184 XXXXXXXXXXXXXVLAASITYRD-DFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDA 242 + AA + YRD D + +LP +++ AY + G+ LF Sbjct: 186 GVGSIFRAPLAGALFAAEVLYRDPDIEGEVVLPAGLSAVVAYCIFCLTYGWGSLF-KAPV 244 Query: 243 EYRFEKAWPLLWFXXXXXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXX 302 + F LL + ++Y + F+ G RL KP Sbjct: 245 NFVFRDPAELLPYTILALVVAAAGWVYVKSFYGVTGFFKRLALPNHFKPVLGGLCTGAIG 304 Query: 303 XXIPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXX 362 PQ L+ GYG+ Q A + IP +++L KI Sbjct: 305 FFFPQTLAFGYGYVQWAISGDPRATIP--FLLILAFGKILTTSFSIGSGGSGGVFGPSVV 362 Query: 363 XXAFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSV 422 +G + G + G D PG FV+V M F VS P++ +I V+EMT S+ + Sbjct: 363 IGGAIGGVV---GMIFHQLGWVDQPGAFVIVGMAGFFTGVSNTPISTIIFVSEMTSSYHL 419 Query: 423 VPGAILAVGIASLLMSRTNVTIYEAQRLN 451 + ++L V S L+SR TIY Q N Sbjct: 420 LLPSLL-VCTVSYLVSR-KWTIYVMQPKN 446 >tr|C1F0W1|C1F0W1_ACIC5 Tax_Id=240015 SubName: Full=Chloride transporter, ClC family;[Acidobacterium capsulatum] Length = 572 Score = 160 bits (404), Expect = 4e-37 Identities = 128/420 (30%), Positives = 182/420 (43%), Gaps = 27/420 (6%) Query: 39 VVFYLALKYTGEFLLGYLADYHIPTPVGEGGSHGSSGFVRPWAIPLITTGGALLSAFIVA 98 + F+ L++ L ++A Y P G H + W IP+ TT G L+S +V Sbjct: 28 LAFHWMLQFCSWLFLRHIAGYLPPDIAGSIAPHSVAVPHWNWWIPVATTVGGLISGALVF 87 Query: 99 RFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPTAQISAGF 158 FAPEA GHGTD + A H IR+R +KMVASA+TI REGPTA I+AGF Sbjct: 88 TFAPEAEGHGTDTVVNAFHRKAGVIRARVAPLKMVASAITIGSGGSAGREGPTALIAAGF 147 Query: 159 CSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRD-DFDYRSLLPGF 217 + + SD++ R + + A + Y +F+ L+ Sbjct: 148 GTLYAKLFKRSDQERRFLILVGMAAGLSAVFRSPIGTAIFAVEVLYSAMEFESHILIYTL 207 Query: 218 ITSGTAYAVLGAFMGFDPLF----GYIDAEYRFEKAWPLLWFXXXXXXXXXXXYLYARVF 273 + S AYAV G F G PLF + +YR A+P W+ + VF Sbjct: 208 LASVVAYAVNGIFFGLQPLFHVPAHLLQPDYR---AYP--WYVFLGLASGIVAAILPMVF 262 Query: 274 HASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAADRNALMAIPLWII 333 + L H +P + KPA PQ+L GYGW Q++ +PL I+ Sbjct: 263 YGMRDLFHAIPCPRIFKPAIGGLCVGLIALYWPQVLGGGYGWMQMSIGG----FLPLDIL 318 Query: 334 IVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELTGLPGVPDAPGIFVVV 393 I L K+ F+GA LG + A G F +V Sbjct: 319 IALLFLKM----LSLSFTVSSGGSGGVFAPSLFIGA---MLGGILAAAFHEPAAG-FAIV 370 Query: 394 AMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMSRTN-----VTIYEAQ 448 M FG+ +R P+A ++MV EMTG + ++ A LAV +A LL S ++YEAQ Sbjct: 371 GMAAVFGAAARVPMATILMVCEMTGGYQLLVPAGLAVILAFLLQSWLTRHLRYHSLYEAQ 430 >tr|C8X5N8|C8X5N8_DESRD Tax_Id=485915 SubName: Full=Cl-channel voltage-gated family protein;[Desulfohalobium retbaense] Length = 605 Score = 159 bits (401), Expect = 1e-36 Identities = 123/433 (28%), Positives = 186/433 (42%), Gaps = 14/433 (3%) Query: 22 KWFXXXXXXXXXXXXXXVVFYLALKYTGEFLLGYLADYHIPTPVGEGG--SHGSSGFVRP 79 KW ++F+ + F L LA Y P P GE + F R Sbjct: 25 KWLLVYILIGVIAGLGSILFHTLCELGMHFFLDGLAGYRPPVPAGEHALLPPTDTPFSR- 83 Query: 80 WAIPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTI 139 W + + G L+S ++V +APEA GHGTD AI+A H IR R ++K VASA+T+ Sbjct: 84 WILLFLPALGGLVSGWLVYTYAPEAEGHGTDSAIDAYHNKGGQIRGRVPIIKTVASAITL 143 Query: 140 XXXXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLA 199 REGP AQI AGF SFL +LGLS+ + R + + A Sbjct: 144 TTGGSGGREGPIAQIGAGFGSFLGNQLGLSERERRIMLAAGVAAGVGSIFRAPMAGALFA 203 Query: 200 ASITYRD-DFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXX 258 A + YR+ +F+ ++P I S AY + G+ LF + F L + Sbjct: 204 AEVLYREPEFESEVIIPAGIASAVAYCIFCLVYGWGSLFH--APNFTFTNPLELGPYALL 261 Query: 259 XXXXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQL 318 ++Y + FH L ++P KPA +PQ L+ GYG Q Sbjct: 262 ALVLTAGGFVYVKCFHGVHALFAKIPIKNHFKPAIGGLLTGGIGFFLPQTLAFGYGVVQQ 321 Query: 319 AADRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELT 378 A + +A+ L + + KI +G + + + Sbjct: 322 AINGELGIALLLGVAL----GKILTTSFTISSGGSGGVFGPSVVIGGALGGGVGQTVDAL 377 Query: 379 GLPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMS 438 LPG+ D PG F++V M F +VS P++ +I V+EMTGS+ ++ ++L + +L Sbjct: 378 -LPGLID-PGAFIIVGMAGFFTAVSNTPVSTIIFVSEMTGSYHLLLPSLLVCFLCQILAQ 435 Query: 439 RTNVTIYEAQRLN 451 + VTIY Q N Sbjct: 436 K--VTIYVEQYAN 446 >tr|A0LKT1|A0LKT1_SYNFM Tax_Id=335543 SubName: Full=Cl-channel, voltage-gated family protein;[Syntrophobacter fumaroxidans] Length = 612 Score = 159 bits (401), Expect = 1e-36 Identities = 122/412 (29%), Positives = 176/412 (42%), Gaps = 11/412 (2%) Query: 42 YLALKYTGEFLLGYLADYHIPTPVGEG-GSHGSSGFVRPWAIPLITTGGALLSAFIVARF 100 + L++T F L YLA Y + P GE + +R W + L+ G LLS IV + Sbjct: 59 FALLEWTSFFCLEYLAGYAVAKPAGEHLVDLVADTPLRRWVLFLLPAFGGLLSGLIVYTW 118 Query: 101 APEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXXXXXXXREGPTAQISAGFCS 160 APEA GHG D I+A H IR+R VK +AS +T+ REGP AQI AG S Sbjct: 119 APEAEGHGMDAFIDAFHNKSGHIRTRVPFVKGIASVITLSTGGSAGREGPIAQIGAGIGS 178 Query: 161 FLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAASITYRDDFDYRSLLPGFITS 220 L R L+ + R + + A + YR+DF+ ++ I+S Sbjct: 179 CLGRAFHLTARERRLMLLAGCAAGLGAIFRAPLGGALTAIEVLYREDFEAEGIVLCIISS 238 Query: 221 GTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXXXXXXXXXYLYARVFHA-SVGL 279 T YA+ A G +P+F F LL++ Y Y ++F+ L Sbjct: 239 VTGYAIFTAIFGHEPIFE--TTALPFSNPVELLFYGILALICVPFGYAYVKIFYGLRDHL 296 Query: 280 AHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAADRNALMAIPLWIIIVLPVA 339 RLP V PA PQ+LS GYG Q A + ++++L Sbjct: 297 FRRLPLKRVFVPALGGLLVGLLGLFAPQVLSGGYGTIQQALKGE----VSAGLLLLLAAL 352 Query: 340 KIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRLGELTGLPGVPDAPGIFVVVAMMTCF 399 KI A +G A+ +L P + PG F +V M F Sbjct: 353 KIVATSFTISSGGSGGVFGPSLFIGAMLGGAVGQLSH-EWFPTLVTQPGGFALVGMGAFF 411 Query: 400 GSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLMSRTNVTIYEAQRLN 451 V++AP+ ++MV EMTG + +V + +A LL R ++YE Q LN Sbjct: 412 AGVAKAPIGALLMVCEMTGGYGLVVPLMFTSVVAILLSQRW--SLYEKQVLN 461 >tr|Q15SM8|Q15SM8_PSEA6 Tax_Id=342610 SubName: Full=Cl-channel, voltage gated;[Pseudoalteromonas atlantica] Length = 544 Score = 158 bits (400), Expect = 1e-36 Identities = 112/375 (29%), Positives = 170/375 (45%), Gaps = 17/375 (4%) Query: 82 IPLITTGGALLSAFIVARFAPEATGHGTDEAIEAVHTNPRSIRSRAVLVKMVASALTIXX 141 +P++TT G L+S IV R APEA GHGTD IEA H + +IRSR VK +ASA+TI Sbjct: 54 VPVVTTLGGLISGVIVYRLAPEAEGHGTDAYIEAFHQHDGAIRSRVPWVKALASAITIGS 113 Query: 142 XXXXXREGPTAQISAGFCSFLTRRLGLSDEDGRTAVXXXXXXXXXXXXXXXXXXXVLAAS 201 REGPTAQI AG + L R GL++ + R + A Sbjct: 114 GGSAGREGPTAQICAGIAAILADRFGLANAERRLLTVVATAAGLSAIFKSPLGSALFAVK 173 Query: 202 ITYRD-DFDYRSLLPGFITSGTAYAVLGAFMGFDPLFGYIDAEYRFEKAWPLLWFXXXXX 260 + Y + R+L + S TAY ++G +G+ P+F I A L W+ Sbjct: 174 VLYSGFSMETRALYFAILASATAYTIMGFVVGWSPIFN-IQAALSLTHPMELSWYVGLGI 232 Query: 261 XXXXXXYLYARVFHASVGLAHRLPGGPVIKPAXXXXXXXXXXXXIPQILSSGYGWAQLAA 320 + +F+ L + IKPA IPQIL GY W +LA Sbjct: 233 ASGIVASIIPTIFYTIRDLFRLINIPHFIKPAIGGLLLGLIAMWIPQILGGGYQWIELAI 292 Query: 321 DRNALMAIPLWIIIVLPVAKIXXXXXXXXXXXXXXXXXXXXXXXAFVGAAIWRL-GELTG 379 + + + L ++++ P+A F+GA + + EL G Sbjct: 293 NHQLSLTVLLVLLLLKPLA--------MALTIGSGGSGGIFAPTLFIGAMLGAVFAELAG 344 Query: 380 -LPGVPDAPGIFVVVAMMTCFGSVSRAPLAVMIMVAEMTGSFSVVPGAILAVGIASLLM- 437 + + + V++ M+ FG+ +R PLA ++M+ EMTG + +V A + V I++L+ Sbjct: 345 AVDSLSPSYASCVIIGMLALFGAAARTPLASLVMIMEMTGEYGLVAPAAVTVVISALVQR 404 Query: 438 ----SRTNVTIYEAQ 448 S T+YE+Q Sbjct: 405 TLTGSLKYPTLYESQ 419 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.325 0.140 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 2,759,427,807 Number of extensions: 93892515 Number of successful extensions: 282580 Number of sequences better than 10.0: 1117 Number of HSP's gapped: 282746 Number of HSP's successfully gapped: 1189 Length of query: 468 Length of database: 3,846,993,858 Length adjustment: 141 Effective length of query: 327 Effective length of database: 2,257,190,235 Effective search space: 738101206845 Effective search space used: 738101206845 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 82 (36.2 bits)