BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_0707 (2414 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HPY9|B2HPY9_MYCMM Tax_Id=216594 (pks6)SubName: Full=Polyket... 4327 0.0 tr|Q82QT4|Q82QT4_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular... 1634 0.0 tr|Q93H87|Q93H87_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular... 1634 0.0 tr|Q8CJN6|Q8CJN6_STRCO Tax_Id=1902 SubName: Full=Putative type I... 1537 0.0 tr|Q93HJ5|Q93HJ5_STRAW Tax_Id=33903 (olmA1)SubName: Full=Modular... 1520 0.0 tr|Q0ILD4|Q0ILD4_9ACTO Tax_Id=204925 (nlmA1)SubName: Full=NlmA1;... 1517 0.0 tr|O54666|O54666_AMYMD Tax_Id=33910 (rifA)SubName: Full=RifA; Su... 1502 0.0 tr|A0FCL1|A0FCL1_STRVO Tax_Id=68280 (merA)SubName: Full=MerA;[St... 1442 0.0 tr|Q1WEK9|Q1WEK9_9ACTO Tax_Id=367779 (merA)SubName: Full=Polyket... 1436 0.0 tr|Q68BG5|Q68BG5_STRHA Tax_Id=1944 (hlsA)SubName: Full=Type I po... 1410 0.0 tr|Q7D9V6|Q7D9V6_MYCTU Tax_Id=1773 SubName: Full=Polyketide synt... 1345 0.0 tr|O86335|O86335_MYCTU Tax_Id=1773 (pks6)SubName: Full=PROBABLE ... 1345 0.0 tr|C6DSJ5|C6DSJ5_MYCTK Tax_Id=478434 SubName: Full=Membrane boun... 1345 0.0 tr|A5TZD1|A5TZD1_MYCTA Tax_Id=419947 (pks6)SubName: Full=Membran... 1345 0.0 tr|A5WJB4|A5WJB4_MYCTF Tax_Id=336982 SubName: Full=Membrane boun... 1345 0.0 tr|A4KE93|A4KE93_MYCTU Tax_Id=395095 SubName: Full=Membrane boun... 1344 0.0 tr|A0ACH3|A0ACH3_STRAM Tax_Id=278992 SubName: Full=Putative type... 1310 0.0 tr|A0QFF5|A0QFF5_MYCA1 Tax_Id=243243 SubName: Full=Erythronolide... 1170 0.0 tr|Q73Z07|Q73Z07_MYCPA Tax_Id=1770 (pks12)SubName: Full=Pks12;[M... 1168 0.0 tr|Q7VES2|Q7VES2_MYCBO Tax_Id=1765 (pks12)SubName: Full=Probable... 1159 0.0 tr|C6DQ18|C6DQ18_MYCTK Tax_Id=478434 SubName: Full=Putative unch... 1159 0.0 tr|C1APW8|C1APW8_MYCBT Tax_Id=561275 (pks12)SubName: Full=Putati... 1159 0.0 tr|A1KK94|A1KK94_MYCBP Tax_Id=410289 (pks12)SubName: Full=Probab... 1159 0.0 tr|A5WP27|A5WP27_MYCTF Tax_Id=336982 SubName: Full=Putative unch... 1159 0.0 tr|A2VJF6|A2VJF6_MYCTU Tax_Id=348776 SubName: Full=Putative unch... 1159 0.0 tr|O53490|O53490_MYCTU Tax_Id=1773 (pks12)SubName: Full=Probable... 1157 0.0 tr|A5U473|A5U473_MYCTA Tax_Id=419947 (pks12)SubName: Full=Polyke... 1157 0.0 tr|Q7D7J7|Q7D7J7_MYCTU Tax_Id=1773 SubName: Full=Polyketide synt... 1152 0.0 tr|B2HF44|B2HF44_MYCMM Tax_Id=216594 (pks12)SubName: Full=Polyke... 1134 0.0 tr|A0PQM7|A0PQM7_MYCUA Tax_Id=362242 (pks12)SubName: Full=Polyke... 1131 0.0 tr|C0Z475|C0Z475_STRVN Tax_Id=1935 (ken14)SubName: Full=Type I p... 1100 0.0 tr|B2HJA3|B2HJA3_MYCMM Tax_Id=216594 SubName: Full=Polyketide sy... 1093 0.0 tr|B2HFX0|B2HFX0_MYCMM Tax_Id=216594 SubName: Full=Polyketide sy... 1068 0.0 tr|Q740I0|Q740I0_MYCPA Tax_Id=1770 (pks8)SubName: Full=Pks8;[Myc... 1057 0.0 tr|Q9X993|Q9X993_9ACTO Tax_Id=68242 (pimS1)SubName: Full=PimS1 p... 1056 0.0 tr|Q7TXK8|Q7TXK8_MYCBO Tax_Id=1765 (pks1)SubName: Full=PROBABLE ... 1045 0.0 tr|C1AG62|C1AG62_MYCBT Tax_Id=561275 (pks1)SubName: Full=Putativ... 1045 0.0 tr|A1KMU1|A1KMU1_MYCBP Tax_Id=410289 (pks1)SubName: Full=Probabl... 1045 0.0 tr|Q9CD81|Q9CD81_MYCLE Tax_Id=1769 SubName: Full=Putative polyke... 1032 0.0 tr|B8ZTY8|B8ZTY8_MYCLB Tax_Id=561304 SubName: Full=Putative poly... 1032 0.0 tr|B2HIL7|B2HIL7_MYCMM Tax_Id=216594 (pks15/1)SubName: Full=Poly... 1027 0.0 tr|D1GLV7|D1GLV7_9ACTO Tax_Id=47763 (slgA3)SubName: Full=Polyket... 1023 0.0 tr|B2HR36|B2HR36_MYCMM Tax_Id=216594 (pks8)SubName: Full=Polyket... 1021 0.0 tr|Q52V46|Q52V46_9ACTO Tax_Id=255848 SubName: Full=Polyketide sy... 1021 0.0 tr|A0PQ25|A0PQ25_MYCUA Tax_Id=362242 (pks15/1)SubName: Full=Poly... 1018 0.0 tr|Q52V49|Q52V49_9ACTO Tax_Id=255848 SubName: Full=Polyketide sy... 1014 0.0 tr|B4VBW0|B4VBW0_9ACTO Tax_Id=465541 SubName: Full=Polyketide sy... 1013 0.0 tr|Q93NW6|Q93NW6_9ACTO Tax_Id=40318 (amphC)SubName: Full=AmphC;[... 1010 0.0 tr|O65933|O65933_MYCTU Tax_Id=1773 (pks8)SubName: Full=Probable ... 1008 0.0 tr|C6DS09|C6DS09_MYCTK Tax_Id=478434 SubName: Full=Polyketide sy... 1008 0.0 >tr|B2HPY9|B2HPY9_MYCMM Tax_Id=216594 (pks6)SubName: Full=Polyketide synthase Pks6;[Mycobacterium marinum] Length = 2414 Score = 4327 bits (11223), Expect = 0.0 Identities = 2222/2414 (92%), Positives = 2223/2414 (92%) Query: 1 VTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC 60 +TDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC Sbjct: 1 MTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC 60 Query: 61 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQV 120 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQV Sbjct: 61 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQV 120 Query: 121 HGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPP 180 HGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPP Sbjct: 121 HGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPP 180 Query: 181 DEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTI 240 DEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTI Sbjct: 181 DEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTI 240 Query: 241 WDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTN 300 WDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTN Sbjct: 241 WDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTN 300 Query: 301 VLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAV 360 VLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAV Sbjct: 301 VLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAV 360 Query: 361 LTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAH 420 LTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAH Sbjct: 361 LTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAH 420 Query: 421 ALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNP 480 ALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNP Sbjct: 421 ALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNP 480 Query: 481 NIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP 540 NIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH GP Sbjct: 481 NIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHVIVEQAVERVVERVVEVGP 540 Query: 541 GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRD 600 GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRD Sbjct: 541 GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRD 600 Query: 601 ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXX 660 ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP Sbjct: 601 ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPVFAAAFDA 660 Query: 661 XXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHS 720 ELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHS Sbjct: 661 VVAELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHS 720 Query: 721 VGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAA 780 VGELSAAHVSG MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAA Sbjct: 721 VGELSAAHVSGVLDLADAALLVVMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAA 780 Query: 781 VNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA 840 VNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA Sbjct: 781 VNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA 840 Query: 841 GRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGL 900 GRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGL Sbjct: 841 GRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGL 900 Query: 901 TSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLP 960 TSLIEESLAQVSVVAVPTLRKDRPEPF DWASVLAGCGGQRVGLP Sbjct: 901 TSLIEESLAQVSVVAVPTLRKDRPEPFAVVGAVAQAFVRGAGVDWASVLAGCGGQRVGLP 960 Query: 961 TYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQ 1020 TYAFAHERFWLADRF L RLQGLSDAEQQ Sbjct: 961 TYAFAHERFWLADRFGVGQQVCVGQVLADEAGPGAHEAAGAAVGQGFAARLQGLSDAEQQ 1020 Query: 1021 AAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAF 1080 AAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAF Sbjct: 1021 AAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAF 1080 Query: 1081 DYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQL 1140 DYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQL Sbjct: 1081 DYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQL 1140 Query: 1141 VASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEAL 1200 VASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEAL Sbjct: 1141 VASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEAL 1200 Query: 1201 AMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQAQWYADTGHIT 1260 AMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQAQWYADTGHIT Sbjct: 1201 AMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQAQWYADTGHIT 1260 Query: 1261 SVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIF 1320 SVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIF Sbjct: 1261 SVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIF 1320 Query: 1321 IGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQ 1380 IGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQ Sbjct: 1321 IGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQ 1380 Query: 1381 DGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGR 1440 DGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGR Sbjct: 1381 DGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGR 1440 Query: 1441 DHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGT 1500 DHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGT Sbjct: 1441 DHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGT 1500 Query: 1501 VQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVS 1560 VQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH GPGVLAWVVS Sbjct: 1501 VQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHVIVEQAVERVVERVVEVGPGVLAWVVS 1560 Query: 1561 ARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAE 1620 ARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAE Sbjct: 1561 ARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAE 1620 Query: 1621 VVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRH 1680 VVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP ELDRH Sbjct: 1621 VVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPVFAAAFDAVVAELDRH 1680 Query: 1681 LARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAH 1740 LARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAH Sbjct: 1681 LARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAH 1740 Query: 1741 VSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVV 1800 VSG MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVV Sbjct: 1741 VSGVLDLADAALLVVMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVV 1800 Query: 1801 LSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVI 1860 LSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVI Sbjct: 1801 LSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVI 1860 Query: 1861 SNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL 1920 SNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL Sbjct: 1861 SNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL 1920 Query: 1921 AQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHER 1980 AQVSVVAVPTLRKDRPEPF DWASVLAGCGGQRVGLPTYAFAHER Sbjct: 1921 AQVSVVAVPTLRKDRPEPFAVVGAVAQAFVRGAGVDWASVLAGCGGQRVGLPTYAFAHER 1980 Query: 1981 FWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVC 2040 FWLADRF L RLQGLSDAEQQAAVLAMVC Sbjct: 1981 FWLADRFGVGQQVCVGQVLADEAGPGAHEAAGAAVGQGFAARLQGLSDAEQQAAVLAMVC 2040 Query: 2041 EHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQL 2100 EHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQL Sbjct: 2041 EHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQL 2100 Query: 2101 ADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPV 2160 ADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPV Sbjct: 2101 ADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPV 2160 Query: 2161 PKREWKEVVLLAGGRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDD 2220 PKREWKEVVLLAGGRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDD Sbjct: 2161 PKREWKEVVLLAGGRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDD 2220 Query: 2221 ALPQDREVVLEGAAQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALI 2280 ALPQDREVVLEGAAQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALI Sbjct: 2221 ALPQDREVVLEGAAQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALI 2280 Query: 2281 DTYLPSQIVNADNPDQVGVNETGALFSRRVTSMARELDQLNXXXXXXXXXXXXXFGTWEP 2340 DTYLPSQIVNADNPDQVGVNETGALFSRRVTSMARELDQLN FGTWEP Sbjct: 2281 DTYLPSQIVNADNPDQVGVNETGALFSRRVTSMARELDQLNATRLTAAASYAALFGTWEP 2340 Query: 2341 VVSAVPLLNMIAMDETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATT 2400 VVSAVPLLNMIAMDETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATT Sbjct: 2341 VVSAVPLLNMIAMDETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATT 2400 Query: 2401 TALHGWISGLIRAG 2414 TALHGWISGLIRAG Sbjct: 2401 TALHGWISGLIRAG 2414 >tr|Q82QT4|Q82QT4_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 7746 Score = 1634 bits (4232), Expect = 0.0 Identities = 954/1926 (49%), Positives = 1167/1926 (60%), Gaps = 50/1926 (2%) Query: 85 SQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARR 144 S+ +A + C+ + + + IAVIG+ACR G W L+E AIT+ P R Sbjct: 4 SELNATGNRDCSA--SADSADGIAVIGLACRLPGAADPAA-FWRLLSEGADAITDVPPDR 60 Query: 145 L-GAAAADWLGDEQETIY-GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALE 202 GA AD ++ I G FL+ + FD FF + P EAA MDPQQRL+LE +W ALE Sbjct: 61 WDGAVVADASAPDRTGIRRGGFLDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALE 120 Query: 203 HAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDN-TGGSSSIIANRLSYFLDV 261 A + TL+ + TGVFVG DY L G TG SIIANR+SYFL + Sbjct: 121 DAHVRAATLRSTRTGVFVGAMWDDYATLHHRSGLTAISPHTVTGLHRSIIANRVSYFLGL 180 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 NGPSL +D+ SSSLV+ HLA +SL GE +A+ G N+ I PE G + G +SP G Sbjct: 181 NGPSLTVDSGQSSSLVSVHLACESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDG 240 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C FDARA+G VRGEG G+VVL+ L+ A G V V+ GSAVN DG +G+ P Sbjct: 241 RCFTFDARANGYVRGEGGGIVVLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQS 300 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSI 441 Q VL A + A ++PA++ YVE HGTGT VGD IEA ALG V G GR+ +PL +GS Sbjct: 301 GQEQVLRLAYERAGVNPADVGYVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSA 360 Query: 442 KPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAV 501 K N+GHLEGAAGI GL+K VL L +L S F PNP IP L L V E EW A Sbjct: 361 KTNVGHLEGAAGITGLLKAVLSLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAE 420 Query: 502 VGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLA--WVVSARTAAGVGAQA 559 GRP AGVSSFG GGTN H G G W +SA+TA+G+ AQA Sbjct: 421 DGRPLLAGVSSFGMGGTNCHIVLASGAAVEAGEGATAGGGAAPTFWPLSAKTASGLRAQA 480 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 LL A L DVG+SL T R+ FEHRAVVVG RD+ L L E+ G + Sbjct: 481 AALLAHTEAPLGLALPDVGWSLATGRTAFEHRAVVVGEVRDDFLRALRELSTGGIDAALT 540 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 +G A P G+ F+F GQG+Q GMGREL P LD L RPLREV++ Sbjct: 541 TGRAGPRGELAFLFSGQGSQRAGMGRELAESVPAFASALDEVCAHLDPLLPRPLREVMFA 600 Query: 680 ----ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXX 735 +A L+ T + Q +LFAVEVAL+RLLESW + P ++MGHS+GEL+AAHV+G Sbjct: 601 PVGTGEAAELDQTLYTQTSLFAVEVALFRLLESWDITPDVLMGHSIGELAAAHVAGVLSL 660 Query: 736 XXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQ---VSVAAVNGPGSVVLSGA 792 RGRLMQALP GG M AVQA E E+R +GE+ VS+AA+NGP SVV+SG Sbjct: 661 ADACALVAARGRLMQALPAGGAMIAVQAAEDEVRARIGERTDRVSIAALNGPDSVVVSGD 720 Query: 793 REAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVT 852 + + + D AA GR+ RL VSHAFHS MEPML +FR VA+ + P IP++SNVT Sbjct: 721 EDLATEIADAFAALGRKTSRLRVSHAFHSPHMEPMLAEFRNVAEGLTFHAPRIPIVSNVT 780 Query: 853 GQLVAEDYG----SADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL 908 G+L E G +A YWVRH+REAVRFAD V G ++E+GP G L S+ Sbjct: 781 GRLSEEPSGYEGCTAAYWVRHVREAVRFADGVARLDEQGVRTYLELGPGGVLASMARAGA 840 Query: 909 AQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQR--VGLPTYAFAH 966 S+ VP LR RPE DW ++ G G R V LPTYAF Sbjct: 841 DSESLF-VPALRTRRPEAQALLAAVASLHVHGVEPDWDALFGGGRGARRKVALPTYAFER 899 Query: 967 ERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAM 1026 +R+WL + RL GL+++E+ AVL M Sbjct: 900 QRYWLDGDTTSPVATTGWAPVAPQPDAIAETDSAPVGALGR--RLAGLAESERDEAVLDM 957 Query: 1027 VCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPT 1086 V H AAVLG A Q++ F D G SLS+VELRN+L TG+ L + FD+PTP Sbjct: 958 VRAHIAAVLGHAEARQVETEWTFKDLGFDSLSSVELRNQLSEATGLRLPSGLLFDHPTPA 1017 Query: 1087 QLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGD 1146 LA HL + A AAA T EPIAIV M CR PGGVSSP LW+L+ASGGD Sbjct: 1018 ALARHLAAQ-SLGGGDAAAAAPATVADPHEPIAIVAMSCRLPGGVSSPEDLWRLLASGGD 1076 Query: 1147 VIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQ 1206 I FP DRGWD+E L+DP+P GK+ TRHGGF+ + A+FD GFFGISP EA A+DPQQ Sbjct: 1077 GISGFPTDRGWDVETLYDPEPGTPGKSSTRHGGFLHEAAEFDAGFFGISPREAAAIDPQQ 1136 Query: 1207 RLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ----AQWYADTGHITSV 1262 RL+LET+WEA E AGIDP LRGS GVF+G YG + + Y TG TSV Sbjct: 1137 RLVLETAWEAFERAGIDPATLRGSRAGVFIGATAQDYGPRLHEPADGVEGYLLTGTTTSV 1196 Query: 1263 ASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIG 1322 ASGR++Y GL GPA++VDTACSSSLVALHLA SLR+GEC +ALAGG TV++TP +F+ Sbjct: 1197 ASGRVAYSFGLEGPAVTVDTACSSSLVALHLAVQSLRSGECTMALAGGVTVMSTPGMFVE 1256 Query: 1323 FSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDG 1382 FSRQRGL+ DGRCKAFA ADGTG++EG GML+++RLSDARR G VLA++ GSAVNQDG Sbjct: 1257 FSRQRGLSADGRCKAFAAGADGTGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDG 1316 Query: 1383 ASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDH 1442 ASNGLTAP+GP+QQRV+ AL+ AG+ ADVD VEAHGTGT LGDPIEA+AL+A YG+ Sbjct: 1317 ASNGLTAPNGPSQQRVVRQALAAAGLAPADVDAVEAHGTGTLLGDPIEAEALIAAYGQGR 1376 Query: 1443 TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQ 1502 D PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP TLH+D+P+ HVDWS V+ Sbjct: 1377 DGDRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPTPHVDWSASGVR 1436 Query: 1503 LLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSAR 1562 LLTEA EWPA PRRA VSSFG+SGTNAH G + WVVSA+ Sbjct: 1437 LLTEAVEWPA-RDLPRRAAVSSFGISGTNAHVIVEQAATSEEPARGTAVAGPVPWVVSAK 1495 Query: 1563 TAAGVGAQAGRLLEFVRA----GRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGL 1618 + + QAGRLL F+ A G + DV SL T+R++ E RA VVG EL GL Sbjct: 1496 SDVALREQAGRLLSFLDAEGVGGAGVRPEDVALSLATSRAVLERRAAVVGGDLAELRQGL 1555 Query: 1619 AEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELD 1678 + G G G GG+ F+F GQG+Q +GMGREL A YP LD Sbjct: 1556 EALASGASGAAPVGGAV--GGRVGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCAFLD 1613 Query: 1679 RHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSA 1738 + D+E LN T QPALFAVEVAL+RLLESWG+RP V GHSVGE++A Sbjct: 1614 APV---------DVDSEELNQTGTTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAA 1664 Query: 1739 AHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGS 1798 AHV+G R LMQALP GG M AVQA E E+ L + V +AAVNGP S Sbjct: 1665 AHVAGVLSLEDAAKLVSARAALMQALPDGGAMVAVQATEDEVLRHLTDGVGIAAVNGPRS 1724 Query: 1799 VVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIP 1858 VV+SGA +AV+ V + A +GR+ RL VSHAFHS LM+PMLE+F AV + IP Sbjct: 1725 VVVSGAEDAVTAVGEIFAGRGRKTSRLKVSHAFHSPLMDPMLEEFAAVVRGLTFSESRIP 1784 Query: 1859 VISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEE 1918 V+SN+TG+L AE Y + +YWVRH+REAVRFAD + G T FVEVGP G L++L + Sbjct: 1785 VVSNLTGRL-AEVY-TPEYWVRHVREAVRFADGIETLGELGVTTFVEVGPGGVLSALAQG 1842 Query: 1919 SLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFA 1977 +V VP LR DRPEP+ DW + G +RV LPTYAF Sbjct: 1843 CFDDGTDIVTVPVLRADRPEPYALVTAIGRLHTHGISPDWQVLFP--GARRVDLPTYAFQ 1900 Query: 1978 HERFWL 1983 ER+WL Sbjct: 1901 RERYWL 1906 Score = 996 bits (2574), Expect = 0.0 Identities = 539/981 (54%), Positives = 651/981 (66%), Gaps = 23/981 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL G + EQ +L +V E A VLG G +A + F + G SL+AVELR+RL T Sbjct: 2445 RLLGATPGEQGRILLDLVREQAATVLGHTGKGAFEADRTFRETGFDSLTAVELRHRLNTA 2504 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRI-DEPIAIVGMGCRYP 1128 TG+ L T FD+PTPT LA HL L ++ AAA T DEP+AIVGM CR P Sbjct: 2505 TGLRLPTTLVFDHPTPTALARHLGEELLGRHGLETAAAQATAAAAADEPLAIVGMSCRLP 2564 Query: 1129 GGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFD 1188 GGV SP LW+L++SG D + FP DRGWDI+ L+DPDPD GKTY+R GGF+ FD Sbjct: 2565 GGVQSPEDLWELLSSGRDAMSGFPTDRGWDIDALYDPDPDRPGKTYSREGGFIQGADRFD 2624 Query: 1189 PGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS 1248 G FGISP EALAMDPQQRLLLET+WEA E AGI ++R S TGVF+G G Y G Sbjct: 2625 AGLFGISPREALAMDPQQRLLLETAWEAFERAGIALASVRASRTGVFIGTNGQDYANGLR 2684 Query: 1249 QA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 A + YA TG SV SGRISY GL GPA++VDTACSSSLVALHLAA +LR+GEC Sbjct: 2685 NAPEEIEGYALTGKAASVVSGRISYTFGLEGPAVTVDTACSSSLVALHLAAQALRSGECS 2744 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 +AL GG TV+ TP +F+ FSRQRGL+ DGRCKAFA ADGTG+ EG G+L+++RLSDARR Sbjct: 2745 MALVGGVTVMTTPDLFVEFSRQRGLSPDGRCKAFAAGADGTGWGEGVGLLLVERLSDARR 2804 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 G VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+ AG+T ADVD VEAHGTGTR Sbjct: 2805 NGHQVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLTPADVDAVEAHGTGTR 2864 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG++H+ D P+WLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP T Sbjct: 2865 LGDPIEAQALLATYGQEHSDDRPVWLGSVKSNIGHTQAAAGVAGVIKMVLAMRHGVLPQT 2924 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH-XXXXXXXXXX 1543 LH+D+P+AHVDWS G V+LLTE +WP G PRRA VSSFG+ GTNAH Sbjct: 2925 LHVDEPTAHVDWSAGAVRLLTEPVQWPGTTG-PRRAAVSSFGIGGTNAHTIIEEAPAAAA 2983 Query: 1544 XXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHR 1603 P + WV+SA++ + AQA RLL F A ++ D G+S TTRS EHR Sbjct: 2984 AEPAREHRPVPVPWVLSAKSEVALRAQAERLLAF--ATDDVSPVDAGFSSATTRSALEHR 3041 Query: 1604 AVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGY 1663 A V+G+ EL AGL + G P V +G A K F+F GQG+Q LGMGREL A Y Sbjct: 3042 AAVIGSDPAELRAGLEALAAGEPAANVVAGRAHSADKVGFLFSGQGSQRLGMGRELYAAY 3101 Query: 1664 PXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGM 1723 P LD + DAE L+ T QPALFAVEVAL+RLLESWG+ Sbjct: 3102 PVFAAAYDEVCALLDATV---------DVDAETLHQTGSTQPALFAVEVALFRLLESWGI 3152 Query: 1724 RPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPL 1783 RP V GHSVGE++AAHV+G R LM+ALP GGVM AVQA E E+ P Sbjct: 3153 RPDYVAGHSVGEIAAAHVAGVLSLEDAAKLVSARAALMKALPAGGVMVAVQAAEDEMLPH 3212 Query: 1784 LGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQF 1843 L ++ +AA+NGP SVV+SGA +AV+ + + AAQGR+ RL VSHAFHS LM+PMLE+F Sbjct: 3213 LIDRAGIAAINGPRSVVISGAEDAVTAIAEVFAAQGRKTSRLKVSHAFHSPLMDPMLEEF 3272 Query: 1844 RAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRF 1903 V + P IPV+SN+TG+L E Y + +YWVRH+REAVRFAD V H G T F Sbjct: 3273 AEVVRGLTFSEPWIPVVSNLTGRL-TESY-TPEYWVRHVREAVRFADGVLTLHELGVTTF 3330 Query: 1904 VEVGPAGGLTSLIEESLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLA 1962 VE+GP G L++L++ L +V +P LR DRPEP DW + Sbjct: 3331 VEIGPGGVLSALVQGCLDDGTDIVTIPALRADRPEPQALTTAYAQLHVSGAEVDWHAFFP 3390 Query: 1963 GCGGQRVGLPTYAFAHERFWL 1983 G +RV LPTYAF ER+WL Sbjct: 3391 --GARRVELPTYAFQRERYWL 3409 Score = 996 bits (2574), Expect = 0.0 Identities = 537/981 (54%), Positives = 646/981 (65%), Gaps = 27/981 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL AE++ VL +V AAVLG A + AF DAG SL++VELRNRL Sbjct: 5867 RLAGLPQAEREQVVLDLVRAEVAAVLGHASAQAVQPEHAFQDAGFDSLTSVELRNRLNAA 5926 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSH---LHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG+ L T FD+PTP L+ LL+ + Q +A AA T DE IAIVGM CR Sbjct: 5927 TGLRLPVTMVFDHPTPVALSRFLLAETLGVQEQAEAAIAAVTGT----DEAIAIVGMACR 5982 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 +PG V SP LW+LVASGGD I FP DRGWD+E L+DPDPD GK+Y RHGGF+ + A+ Sbjct: 5983 FPGDVRSPEDLWRLVASGGDAISGFPEDRGWDVENLYDPDPDRSGKSYVRHGGFLHEAAE 6042 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFGISP EALAMDPQQRLLLETSWEA E AGIDP +RGS TGVF G+ YG Sbjct: 6043 FDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATVRGSRTGVFAGVMYHDYGGR 6102 Query: 1247 TSQA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGE 1302 A Y +G S+ASGR+SY GL GPA++VDTACSSSLVALHLA +LR+GE Sbjct: 6103 VKTAPEGMDAYLGSGSAGSIASGRVSYTFGLEGPAVTVDTACSSSLVALHLATQALRSGE 6162 Query: 1303 CDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDA 1362 C +AL GG TV+ATPS F+ FSRQRGL+ DGRCKAFA ADGTG++EGAGML+++RLSDA Sbjct: 6163 CSMALVGGVTVMATPSTFVEFSRQRGLSADGRCKAFAAGADGTGWAEGAGMLLVERLSDA 6222 Query: 1363 RRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTG 1422 RR G VLA++ G+AVNQDGASNGLTAP+GP+QQRVI AL++AG++ VD VEAHGTG Sbjct: 6223 RRNGHTVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAGVSSEQVDAVEAHGTG 6282 Query: 1423 TRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLP 1482 T+LGDPIEAQAL+ATYG++ D PLWLGS+KSN+GH+QAAAGV GVIKMV AMRH LP Sbjct: 6283 TKLGDPIEAQALIATYGQERPGDRPLWLGSLKSNIGHAQAAAGVGGVIKMVMAMRHGALP 6342 Query: 1483 ATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXX 1542 TLH+D+P+ HVDWS G V+LLTEA EWP PRRA VSSFG+SGTNAH Sbjct: 6343 RTLHVDEPTPHVDWSAGDVRLLTEAMEWPE-TDHPRRAAVSSFGISGTNAHVIVEQAPDT 6401 Query: 1543 XXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEH 1602 + WV+S RT A + AQA RLL V +L D+G+SL TTRS EH Sbjct: 6402 AELPPVPDSGKAVPWVLSGRTEAALRAQAERLLSLV-PEMDLPPADIGFSLATTRSAMEH 6460 Query: 1603 RAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAG 1662 RA VVG RDELL GL + G P V G GGK+ F+F GQG+Q +GMGREL Sbjct: 6461 RAAVVGESRDELLEGLRALAAGSPSTRVVLGEPGAGGKSGFLFSGQGSQRIGMGRELYDA 6520 Query: 1663 YPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWG 1722 +P +D + D+E LN T QPALFAVEVAL+RLLESWG Sbjct: 6521 FPVFAAAYDEVCALVDAPV---------DVDSEELNQTGTTQPALFAVEVALFRLLESWG 6571 Query: 1723 MRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRP 1782 +RP V GHSVGE++AAHV+G R LMQALP G M AVQA E E+ P Sbjct: 6572 IRPDYVAGHSVGEIAAAHVAGVLSLEDAAKLVSARAALMQALPADGAMVAVQATEDEVLP 6631 Query: 1783 LLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQ 1842 L + V +AAVNGP SVV+SGA + V + + +GR+ RL VSHAFHS LM+PMLE+ Sbjct: 6632 HLTDGVGIAAVNGPQSVVVSGAEDVVVAIGEAFRERGRKTSRLKVSHAFHSPLMDPMLEE 6691 Query: 1843 FRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATR 1902 F + P +PV+SN+TG+L AE Y + +YWVRH+REAVRFAD + H G T Sbjct: 6692 FAEAVSGLSFNEPRLPVVSNLTGRL-AEPY-TPEYWVRHVREAVRFADGLHTLHELGVTT 6749 Query: 1903 FVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLA 1962 FVE+GP GG+ S + + +V VP +R DRPEP DW ++ Sbjct: 6750 FVEIGP-GGVLSALAQGCLDGDIVTVPAVRTDRPEPQAVVTALAELHAHGVSPDWRALFP 6808 Query: 1963 GCGGQRVGLPTYAFAHERFWL 1983 G +RV LPTY F +ER WL Sbjct: 6809 --GARRVDLPTYPFQYERLWL 6827 Score = 987 bits (2551), Expect = 0.0 Identities = 541/985 (54%), Positives = 652/985 (66%), Gaps = 30/985 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL++AE++ VL +V AAVLG GA + A +F D G SL+AVELRNRL + Sbjct: 4178 RLAGLAEAEREQVVLDLVRTEVAAVLGHAGAQSVGADDSFKDIGFDSLTAVELRNRLNSA 4237 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLH--HQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 G+ L AT FDYP P LA L + P DEPIAIVGM CRY Sbjct: 4238 VGMRLPATLIFDYPNPLTLAHFLTGEAAGGEAATAVPTTLSTATGTADEPIAIVGMACRY 4297 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGGV SP LWQLV SG D + FP RGWD+E+L+DP+PD G +YTR GGF+ D ADF Sbjct: 4298 PGGVQSPEDLWQLVFSGRDAVSGFPEGRGWDVEQLYDPNPDQWGTSYTREGGFLHDAADF 4357 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--L 1245 D FFGISP EALAMDPQQRLLLETSWEA E AGIDP +RGS TGVF G+ YG + Sbjct: 4358 DAEFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATVRGSRTGVFAGVMYHDYGGRV 4417 Query: 1246 GTSQA--QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGEC 1303 TS + Y G S+ASGR+SY GL GPA++VDTACSSSLVALHLAA +LR+GEC Sbjct: 4418 HTSPPGLEGYLVNGSAGSIASGRVSYTFGLEGPAVTVDTACSSSLVALHLAAQALRSGEC 4477 Query: 1304 DLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDAR 1363 +AL GG TV+A PS+F+ FSRQRGL+ DGRCKAF ADGTG++EG GML+++RLSDAR Sbjct: 4478 SMALVGGVTVMAGPSVFVEFSRQRGLSADGRCKAFGAGADGTGWAEGVGMLLVERLSDAR 4537 Query: 1364 RAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGT 1423 R G VLA++ G+AVNQDGASNGLTAP+GP+QQRVI AL++AG++ +VD VEAHGTGT Sbjct: 4538 RNGHKVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAGLSSDEVDAVEAHGTGT 4597 Query: 1424 RLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPA 1483 RLGDPIEAQAL+ATYG++ + D PLWLGS+KSN+GHSQAAAGV GVIKMV AM+H +LP Sbjct: 4598 RLGDPIEAQALIATYGQERSEDRPLWLGSLKSNIGHSQAAAGVGGVIKMVMAMQHGVLPQ 4657 Query: 1484 TLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXX 1543 TLH+D+P+ HVDWS G VQLLTEA EWPA G PRRA VSSFGVSGTNAH Sbjct: 4658 TLHVDEPTPHVDWSAGAVQLLTEAVEWPASDG-PRRAAVSSFGVSGTNAHVIVEQAATSE 4716 Query: 1544 XXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRA----GRELDAGDVGYSLVTTRSL 1599 G + WV+SA++ A + QAGRLL F+ A G + DV YSL T+R++ Sbjct: 4717 VTARGTAVAGPVPWVLSAKSDAALREQAGRLLSFLDAEGVGGAGVRPEDVAYSLATSRAV 4776 Query: 1600 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 1659 E RA VVG E GL +V G VG A GG+ F+F GQG+Q +GMGREL Sbjct: 4777 LECRAAVVGEELGEFRQGLEGIVSGAAPVGGA-----VGGRVGFLFSGQGSQRIGMGREL 4831 Query: 1660 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 1719 A YP LD + DAE L+ T QPALFAVEVAL+RLLE Sbjct: 4832 YAAYPVFAAAYDEVCALLDATV---------DVDAETLHQTGSTQPALFAVEVALFRLLE 4882 Query: 1720 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 1779 SWG+RP V GHSVGE++AAHV+G R LMQALP GG M A+QA E E Sbjct: 4883 SWGIRPDYVAGHSVGEIAAAHVAGVLSLEDAAKLVSARAALMQALPAGGAMVAIQATEAE 4942 Query: 1780 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 1839 + P L V +AA+NGP SVVLSG+ +AV + + A QGR+ RL VSHAFHS LM+PM Sbjct: 4943 VLPHLTHGVGLAAINGPRSVVLSGSEDAVLDIAEVFAQQGRKTSRLKVSHAFHSPLMDPM 5002 Query: 1840 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 1899 LE+F V + P IPV+SN+TG+L AE Y +YWVRH+REAVRFAD + H G Sbjct: 5003 LEEFAEVVRGLTFSEPRIPVVSNLTGRL-AEVY-IPEYWVRHVREAVRFADGLHTLHELG 5060 Query: 1900 ATRFVEVGPAGGLTSLIEESLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWA 1958 T FVE+GP G L++L++ L +V VP LR DRPEP+ +W Sbjct: 5061 VTMFVEIGPGGVLSALVQGCLDDGTHIVTVPALRADRPEPYALVTAVGQLHTHGISPEWQ 5120 Query: 1959 SVLAGCGGQRVGLPTYAFAHERFWL 1983 ++ G +RV LPTYAF ER+WL Sbjct: 5121 ALFP--GARRVDLPTYAFQRERYWL 5143 Score = 743 bits (1919), Expect = 0.0 Identities = 442/1007 (43%), Positives = 573/1007 (56%), Gaps = 27/1007 (2%) Query: 1118 IAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRH 1177 IA++G+ CR PG + PA W+L++ G D I + PPDR WD + D A +T R Sbjct: 24 IAVIGLACRLPGA-ADPAAFWRLLSEGADAITDVPPDR-WDGAVV--ADASAPDRTGIRR 79 Query: 1178 GGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVG 1237 GGF+ + DFD GFFG+SP EA AMDPQQRL+LE +WEALEDA + LR + TGVFVG Sbjct: 80 GGFLDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALEDAHVRAATLRSTRTGVFVG 139 Query: 1238 IYGDGYGL-----GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 D Y G + + TG S+ + R+SY LGL GP+++VD+ SSSLV++H Sbjct: 140 AMWDDYATLHHRSGLTAISPHTVTGLHRSIIANRVSYFLGLNGPSLTVDSGQSSSLVSVH 199 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 LA SLR GE +ALAGG + P +G ++ GL+ DGRC F A+G EG G Sbjct: 200 LACESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDGRCFTFDARANGYVRGEGGG 259 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 ++VL+ L+ A G PV ++ GSAVN DG +GLT P Q++V+ A AG+ AD Sbjct: 260 IVVLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQSGQEQVLRLAYERAGVNPAD 319 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKM 1472 V VE HGTGT++GDPIEA AL A G P PL +GS K+N+GH + AAG+ G++K Sbjct: 320 VGYVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSAKTNVGHLEGAAGITGLLKA 379 Query: 1473 VEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNA 1532 V ++ H+ LPA+L+ P+ + +++ TE EW A GRP AGVSSFG+ GTN Sbjct: 380 VLSLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAEDGRPLLAGVSSFGMGGTNC 439 Query: 1533 HXXXXXXXXXXXXXXXXXGPGVLA--WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVG 1590 H G G W +SA+TA+G+ AQA LL A L DVG Sbjct: 440 HIVLASGAAVEAGEGATAGGGAAPTFWPLSAKTASGLRAQAAALLAHTEAPLGLALPDVG 499 Query: 1591 YSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGA 1650 +SL T R+ FEHRAVVVG RD+ L L E+ G + +G A P G+ F+F GQG+ Sbjct: 500 WSLATGRTAFEHRAVVVGEVRDDFLRALRELSTGGIDAALTTGRAGPRGELAFLFSGQGS 559 Query: 1651 QWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG----ADAELLNTTEFAQPA 1706 Q GMGREL P LD L RPLREV++ +A L+ T + Q + Sbjct: 560 QRAGMGRELAESVPAFASALDEVCAHLDPLLPRPLREVMFAPVGTGEAAELDQTLYTQTS 619 Query: 1707 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 1766 LFAVEVAL+RLLESW + P ++MGHS+GEL+AAHV+G RGRLMQALP Sbjct: 620 LFAVEVALFRLLESWDITPDVLMGHSIGELAAAHVAGVLSLADACALVAARGRLMQALPA 679 Query: 1767 GGVMYAVQAGEQELRPLLGEQ---VSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 1823 GG M AVQA E E+R +GE+ VS+AA+NGP SVV+SG + + + D AA GR+ Sbjct: 680 GGAMIAVQAAEDEVRARIGERTDRVSIAALNGPDSVVVSGDEDLATEIADAFAALGRKTS 739 Query: 1824 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYG----SADYWV 1879 RL VSHAFHS MEPML +FR VA+ + P IP++SNVTG+L E G +A YWV Sbjct: 740 RLRVSHAFHSPHMEPMLAEFRNVAEGLTFHAPRIPIVSNVTGRLSEEPSGYEGCTAAYWV 799 Query: 1880 RHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPF 1939 RH+REAVRFAD V G ++E+GP G L S+ S+ VP LR RPE Sbjct: 800 RHVREAVRFADGVARLDEQGVRTYLELGPGGVLASMARAGADSESLF-VPALRTRRPEAQ 858 Query: 1940 XXXXXXXXXXXXXXXXDWASVLAGCGGQR--VGLPTYAFAHERFWLADRFXXXXXXXXXX 1997 DW ++ G G R V LPTYAF +R+WL Sbjct: 859 ALLAAVASLHVHGVEPDWDALFGGGRGARRKVALPTYAFERQRYWLDGDTTSPVATTGWA 918 Query: 1998 XLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDA 2057 + RL GL+++E+ AVL MV H AAVLG A Q++ Sbjct: 919 PVAPQPDAIAETDSAPVGALGR--RLAGLAESERDEAVLDMVRAHIAAVLGHAEARQVET 976 Query: 2058 GQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHL 2104 F D G SLS+VELRN+L TG+ L + FD+PTP LA HL Sbjct: 977 EWTFKDLGFDSLSSVELRNQLSEATGLRLPSGLLFDHPTPAALARHL 1023 Score = 707 bits (1825), Expect = 0.0 Identities = 409/950 (43%), Positives = 555/950 (58%), Gaps = 32/950 (3%) Query: 33 DLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPS----AHDVIKSVLGGDGSQRS 88 D R+ G S+ + + L+ G+ +P V+D+P+ A + + +LG G + + Sbjct: 2481 DRTFRETGFDSLTAVELRHRLNTATGLRLPTTLVFDHPTPTALARHLGEELLGRHGLETA 2540 Query: 89 ADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAA 148 A T A +EP+A++GM+CR G V LW+ L+ + A++ +P R Sbjct: 2541 AAQATAAAA-----ADEPLAIVGMSCRLPGGVQSPEDLWELLSSGRDAMSGFPTDRGWDI 2595 Query: 149 AADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEH 203 A + D + G F++ + FD F I P EA MDPQQRLLLET+W A E Sbjct: 2596 DALYDPDPDRPGKTYSREGGFIQGADRFDAGLFGISPREALAMDPQQRLLLETAWEAFER 2655 Query: 204 AGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNG 263 AGI +++ S TGVF+G + DY L + + TG ++S+++ R+SY + G Sbjct: 2656 AGIALASVRASRTGVFIGTNGQDYANGLRNAPEEIEGYALTGKAASVVSGRISYTFGLEG 2715 Query: 264 PSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSC 323 P++ +DTACSSSLVA HLA ++L SGEC +A+V G V+ +P+++ F +SP G C Sbjct: 2716 PAVTVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMTTPDLFVEFSRQRGLSPDGRC 2775 Query: 324 RAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQ 383 +AF A ADG GEG G++++ERLSDARR G VLA++ GSAVNQDG SNG+ APN +Q Sbjct: 2776 KAFAAGADGTGWGEGVGLLLVERLSDARRNGHQVLALVRGSAVNQDGASNGLTAPNGPSQ 2835 Query: 384 ISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKP 443 V+ A A + PA++D VEAHGTGT +GD IEA AL +G+ +P+ +GS+K Sbjct: 2836 QRVIRQALASAGLTPADVDAVEAHGTGTRLGDPIEAQALLATYGQEHSDDRPVWLGSVKS 2895 Query: 444 NIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVG 503 NIGH + AAG+AG+IK VL ++ G L + + P ++ ++ + ++ E +WP G Sbjct: 2896 NIGHTQAAAGVAGVIKMVLAMRHGVLPQTLHVDEPTAHVDWSAGAVRLLTEPVQWPGTTG 2955 Query: 504 RPRRAGVSSFGFGGTNAH-XXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRL 562 PRRA VSSFG GGTNAH P + WV+SA++ + AQA RL Sbjct: 2956 -PRRAAVSSFGIGGTNAHTIIEEAPAAAAAEPAREHRPVPVPWVLSAKSEVALRAQAERL 3014 Query: 563 LEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGV 622 L F A ++ D G+S TTRS EHRA V+G+ EL AGL + G P V +G Sbjct: 3015 LAF--ATDDVSPVDAGFSSATTRSALEHRAAVIGSDPAELRAGLEALAAGEPAANVVAGR 3072 Query: 623 AMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADA 682 A K F+F GQG+Q LGMGREL A YP LD + DA Sbjct: 3073 AHSADKVGFLFSGQGSQRLGMGRELYAAYPVFAAAYDEVCALLDATV---------DVDA 3123 Query: 683 ELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXX 742 E L+ T QPALFAVEVAL+RLLESWG+RP V GHSVGE++AAHV+G Sbjct: 3124 ETLHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLSLEDAAKLV 3183 Query: 743 XMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDR 802 R LM+ALP GGVM AVQA E E+ P L ++ +AA+NGP SVV+SGA +AV+ + + Sbjct: 3184 SARAALMKALPAGGVMVAVQAAEDEMLPHLIDRAGIAAINGPRSVVISGAEDAVTAIAEV 3243 Query: 803 LAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGS 862 AAQGR+ RL VSHAFHS LM+PMLE+F V + P IPV+SN+TG+L E Y + Sbjct: 3244 FAAQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSEPWIPVVSNLTGRL-TESY-T 3301 Query: 863 ADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQ-VSVVAVPTLRK 921 +YWVRH+REAVRFAD V H G T FVE+GP G L++L++ L +V +P LR Sbjct: 3302 PEYWVRHVREAVRFADGVLTLHELGVTTFVEIGPGGVLSALVQGCLDDGTDIVTIPALRA 3361 Query: 922 DRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 DRPEP DW + G +RV LPTYAF ER+WL Sbjct: 3362 DRPEPQALTTAYAQLHVSGAEVDWHAFFP--GARRVELPTYAFQRERYWL 3409 Score = 697 bits (1798), Expect = 0.0 Identities = 422/970 (43%), Positives = 551/970 (56%), Gaps = 42/970 (4%) Query: 19 IAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIK 77 +AA G A+ V D +D+G S+ + + L+ +G+ +P ++D P+ + Sbjct: 4199 VAAVLGHAGAQSVGADDSFKDIGFDSLTAVELRNRLNSAVGMRLPATLIFDYPNPLTLAH 4258 Query: 78 SVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAI 137 + G +A + G +EPIA++GMACR+ G V LW + + A+ Sbjct: 4259 FLTGEAAGGEAATAVPTTLSTATGTADEPIAIVGMACRYPGGVQSPEDLWQLVFSGRDAV 4318 Query: 138 TEYPARRLGAAAA--DWLGDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRL 192 + +P R D D+ T Y G FL D FD +FF I P EA MDPQQRL Sbjct: 4319 SGFPEGRGWDVEQLYDPNPDQWGTSYTREGGFLHDAADFDAEFFGISPREALAMDPQQRL 4378 Query: 193 LLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDN------TGG 246 LLETSW A E AGI P T++ S TGVF GV DY GGR T G Sbjct: 4379 LLETSWEAFERAGIDPATVRGSRTGVFAGVMYHDY------GGRVHTSPPGLEGYLVNGS 4432 Query: 247 SSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPE 306 + SI + R+SY + GP++ +DTACSSSLVA HLA ++L SGEC +A+V G V+ P Sbjct: 4433 AGSIASGRVSYTFGLEGPAVTVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMAGPS 4492 Query: 307 VWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAV 366 V+ F +S G C+AF A ADG EG G++++ERLSDARR G VLAV+ G+AV Sbjct: 4493 VFVEFSRQRGLSADGRCKAFGAGADGTGWAEGVGMLLVERLSDARRNGHKVLAVVRGTAV 4552 Query: 367 NQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVF 426 NQDG SNG+ APN +Q V+ A A + E+D VEAHGTGT +GD IEA AL + Sbjct: 4553 NQDGASNGLTAPNGPSQQRVIRQALANAGLSSDEVDAVEAHGTGTRLGDPIEAQALIATY 4612 Query: 427 GRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAE 486 G+ R +PL +GS+K NIGH + AAG+ G+IK V+ +Q G L + + P P++ ++ Sbjct: 4613 GQERSEDRPLWLGSLKSNIGHSQAAAGVGGVIKMVMAMQHGVLPQTLHVDEPTPHVDWSA 4672 Query: 487 LGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWV 546 + ++ E EWPA G PRRA VSSFG GTNAH G + WV Sbjct: 4673 GAVQLLTEAVEWPASDG-PRRAAVSSFGVSGTNAHVIVEQAATSEVTARGTAVAGPVPWV 4731 Query: 547 VSARTAAGVGAQAGRLLEFVRA----GRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDEL 602 +SA++ A + QAGRLL F+ A G + DV YSL T+R++ E RA VVG E Sbjct: 4732 LSAKSDAALREQAGRLLSFLDAEGVGGAGVRPEDVAYSLATSRAVLECRAAVVGEELGEF 4791 Query: 603 LAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXX 662 GL +V G VG A GG+ F+F GQG+Q +GMGREL A YP Sbjct: 4792 RQGLEGIVSGAAPVGGA-----VGGRVGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVC 4846 Query: 663 XELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVG 722 LD + DAE L+ T QPALFAVEVAL+RLLESWG+RP V GHSVG Sbjct: 4847 ALLDATV---------DVDAETLHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVG 4897 Query: 723 ELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVN 782 E++AAHV+G R LMQALP GG M A+QA E E+ P L V +AA+N Sbjct: 4898 EIAAAHVAGVLSLEDAAKLVSARAALMQALPAGGAMVAIQATEAEVLPHLTHGVGLAAIN 4957 Query: 783 GPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGR 842 GP SVVLSG+ +AV + + A QGR+ RL VSHAFHS LM+PMLE+F V + Sbjct: 4958 GPRSVVLSGSEDAVLDIAEVFAQQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSE 5017 Query: 843 PAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTS 902 P IPV+SN+TG+L AE Y +YWVRH+REAVRFAD + H G T FVE+GP G L++ Sbjct: 5018 PRIPVVSNLTGRL-AEVY-IPEYWVRHVREAVRFADGLHTLHELGVTMFVEIGPGGVLSA 5075 Query: 903 LIEESLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPT 961 L++ L +V VP LR DRPEP+ +W ++ G +RV LPT Sbjct: 5076 LVQGCLDDGTHIVTVPALRADRPEPYALVTAVGQLHTHGISPEWQALFP--GARRVDLPT 5133 Query: 962 YAFAHERFWL 971 YAF ER+WL Sbjct: 5134 YAFQRERYWL 5143 Score = 695 bits (1793), Expect = 0.0 Identities = 420/975 (43%), Positives = 550/975 (56%), Gaps = 57/975 (5%) Query: 19 IAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIK 77 +AA G SA+ V + +D G S+ + + L+ G+ +P V+D+P+ + + Sbjct: 5888 VAAVLGHASAQAVQPEHAFQDAGFDSLTSVELRNRLNAATGLRLPVTMVFDHPTPVALSR 5947 Query: 78 SVLGGD-GSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSA 136 +L G Q A++ AV G T+E IA++GMACRF G V LW +A A Sbjct: 5948 FLLAETLGVQEQAEAAIA-AVTG---TDEAIAIVGMACRFPGDVRSPEDLWRLVASGGDA 6003 Query: 137 ITEYPARRLGAAAADWLGDEQETIY--------------GCFLEDVEGFDNKFFDIPPDE 182 I+ +P R G + E +Y G FL + FD FF I P E Sbjct: 6004 ISGFPEDR---------GWDVENLYDPDPDRSGKSYVRHGGFLHEAAEFDPAFFGISPRE 6054 Query: 183 AALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWD 242 A MDPQQRLLLETSW A E AGI P T++ S TGVF GV DY GGR T + Sbjct: 6055 ALAMDPQQRLLLETSWEAFERAGIDPATVRGSRTGVFAGVMYHDY------GGRVKTAPE 6108 Query: 243 N------TGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVV 296 +G + SI + R+SY + GP++ +DTACSSSLVA HLA ++L SGEC +A+V Sbjct: 6109 GMDAYLGSGSAGSIASGRVSYTFGLEGPAVTVDTACSSSLVALHLATQALRSGECSMALV 6168 Query: 297 AGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRT 356 G V+ +P + F +S G C+AF A ADG EG G++++ERLSDARR G T Sbjct: 6169 GGVTVMATPSTFVEFSRQRGLSADGRCKAFAAGADGTGWAEGAGMLLVERLSDARRNGHT 6228 Query: 357 VLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDR 416 VLAV+ G+AVNQDG SNG+ APN +Q V+ A A + ++D VEAHGTGT +GD Sbjct: 6229 VLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAGVSSEQVDAVEAHGTGTKLGDP 6288 Query: 417 IEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFE 476 IEA AL +G+ R +PL +GS+K NIGH + AAG+ G+IK V+ ++ G L + + Sbjct: 6289 IEAQALIATYGQERPGDRPLWLGSLKSNIGHAQAAAGVGGVIKMVMAMRHGALPRTLHVD 6348 Query: 477 VPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXX 536 P P++ ++ + ++ E EWP PRRA VSSFG GTNAH Sbjct: 6349 EPTPHVDWSAGDVRLLTEAMEWPE-TDHPRRAAVSSFGISGTNAHVIVEQAPDTAELPPV 6407 Query: 537 XXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVG 596 + WV+S RT A + AQA RLL V +L D+G+SL TTRS EHRA VVG Sbjct: 6408 PDSGKAVPWVLSGRTEAALRAQAERLLSLV-PEMDLPPADIGFSLATTRSAMEHRAAVVG 6466 Query: 597 AGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXX 656 RDELL GL + G P V G GGK+ F+F GQG+Q +GMGREL +P Sbjct: 6467 ESRDELLEGLRALAAGSPSTRVVLGEPGAGGKSGFLFSGQGSQRIGMGRELYDAFPVFAA 6526 Query: 657 XXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLV 716 +D + D+E LN T QPALFAVEVAL+RLLESWG+RP V Sbjct: 6527 AYDEVCALVDAPV---------DVDSEELNQTGTTQPALFAVEVALFRLLESWGIRPDYV 6577 Query: 717 MGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQV 776 GHSVGE++AAHV+G R LMQALP G M AVQA E E+ P L + V Sbjct: 6578 AGHSVGEIAAAHVAGVLSLEDAAKLVSARAALMQALPADGAMVAVQATEDEVLPHLTDGV 6637 Query: 777 SVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVAD 836 +AAVNGP SVV+SGA + V + + +GR+ RL VSHAFHS LM+PMLE+F Sbjct: 6638 GIAAVNGPQSVVVSGAEDVVVAIGEAFRERGRKTSRLKVSHAFHSPLMDPMLEEFAEAVS 6697 Query: 837 EVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGP 896 + P +PV+SN+TG+L AE Y + +YWVRH+REAVRFAD + H G T FVE+GP Sbjct: 6698 GLSFNEPRLPVVSNLTGRL-AEPY-TPEYWVRHVREAVRFADGLHTLHELGVTTFVEIGP 6755 Query: 897 AGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQR 956 GG+ S + + +V VP +R DRPEP DW ++ G +R Sbjct: 6756 -GGVLSALAQGCLDGDIVTVPAVRTDRPEPQAVVTALAELHAHGVSPDWRALFP--GARR 6812 Query: 957 VGLPTYAFAHERFWL 971 V LPTY F +ER WL Sbjct: 6813 VDLPTYPFQYERLWL 6827 Score = 690 bits (1780), Expect = 0.0 Identities = 420/988 (42%), Positives = 559/988 (56%), Gaps = 58/988 (5%) Query: 9 DALQEWFTHYIAARTG-CDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVW 67 +A+ + +IAA G ++ +V + +DLG S+ + + +LS+ G+ +P ++ Sbjct: 952 EAVLDMVRAHIAAVLGHAEARQVETEWTFKDLGFDSLSSVELRNQLSEATGLRLPSGLLF 1011 Query: 68 DNPSA-----HDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHG 122 D+P+ H +S+ GGD + A +EPIA++ M+CR G V Sbjct: 1012 DHPTPAALARHLAAQSLGGGDAA--------AAAPATVADPHEPIAIVAMSCRLPGGVSS 1063 Query: 123 VGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIY--------------GCFLEDV 168 LW LA I+ +P R G + ET+Y G FL + Sbjct: 1064 PEDLWRLLASGGDGISGFPTDR---------GWDVETLYDPEPGTPGKSSTRHGGFLHEA 1114 Query: 169 EGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYV 228 FD FF I P EAA +DPQQRL+LET+W A E AGI P TL+ S GVF+G ++ DY Sbjct: 1115 AEFDAGFFGISPREAAAIDPQQRLVLETAWEAFERAGIDPATLRGSRAGVFIGATAQDYG 1174 Query: 229 RLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLAS 288 L + TG ++S+ + R++Y + GP++ +DTACSSSLVA HLA +SL S Sbjct: 1175 PRLHEPADGVEGYLLTGTTTSVASGRVAYSFGLEGPAVTVDTACSSSLVALHLAVQSLRS 1234 Query: 289 GECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLS 348 GEC +A+ G V+ +P ++ F +S G C+AF A ADG EG G++++ERLS Sbjct: 1235 GECTMALAGGVTVMSTPGMFVEFSRQRGLSADGRCKAFAAGADGTGWAEGVGMLLVERLS 1294 Query: 349 DARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHG 408 DARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ A A + PA++D VEAHG Sbjct: 1295 DARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRQALAAAGLAPADVDAVEAHG 1354 Query: 409 TGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQ 468 TGT +GD IEA AL +G+GR +PL +GS+K NIGH + AAG+AG+IK V+ ++ G Sbjct: 1355 TGTLLGDPIEAEALIAAYGQGRDGDRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGV 1414 Query: 469 LLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXX 528 L + + P P++ ++ G+ ++ E EWPA PRRA VSSFG GTNAH Sbjct: 1415 LPRTLHVDEPTPHVDWSASGVRLLTEAVEWPA-RDLPRRAAVSSFGISGTNAHVIVEQAA 1473 Query: 529 XXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRA----GRELDAGDVGYSLVTT 584 G + WVVSA++ + QAGRLL F+ A G + DV SL T+ Sbjct: 1474 TSEEPARGTAVAGPVPWVVSAKSDVALREQAGRLLSFLDAEGVGGAGVRPEDVALSLATS 1533 Query: 585 RSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMG 644 R++ E RA VVG EL GL + G G G GG+ F+F GQG+Q +GMG Sbjct: 1534 RAVLERRAAVVGGDLAELRQGLEALASGASGAAPVGGAV--GGRVGFLFSGQGSQRIGMG 1591 Query: 645 RELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYR 704 REL A YP LD + D+E LN T QPALFAVEVAL+R Sbjct: 1592 RELYAAYPVFAAAYDEVCAFLDAPV---------DVDSEELNQTGTTQPALFAVEVALFR 1642 Query: 705 LLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAG 764 LLESWG+RP V GHSVGE++AAHV+G R LMQALP GG M AVQA Sbjct: 1643 LLESWGIRPDYVAGHSVGEIAAAHVAGVLSLEDAAKLVSARAALMQALPDGGAMVAVQAT 1702 Query: 765 EQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLM 824 E E+ L + V +AAVNGP SVV+SGA +AV+ V + A +GR+ RL VSHAFHS LM Sbjct: 1703 EDEVLRHLTDGVGIAAVNGPRSVVVSGAEDAVTAVGEIFAGRGRKTSRLKVSHAFHSPLM 1762 Query: 825 EPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAH 884 +PMLE+F AV + IPV+SN+TG+L AE Y + +YWVRH+REAVRFAD + Sbjct: 1763 DPMLEEFAAVVRGLTFSESRIPVVSNLTGRL-AEVY-TPEYWVRHVREAVRFADGIETLG 1820 Query: 885 SAGATRFVEVGPAGGLTSLIEESLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXX 943 G T FVEVGP G L++L + +V VP LR DRPEP+ Sbjct: 1821 ELGVTTFVEVGPGGVLSALAQGCFDDGTDIVTVPVLRADRPEPYALVTAIGRLHTHGISP 1880 Query: 944 DWASVLAGCGGQRVGLPTYAFAHERFWL 971 DW + G +RV LPTYAF ER+WL Sbjct: 1881 DWQVLFP--GARRVDLPTYAFQRERYWL 1906 Score = 78.6 bits (192), Expect = 1e-11 Identities = 42/83 (50%), Positives = 52/83 (62%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL++AE++ VL +V AAVLG GA + A +F D G SL+AVELRNRL + Sbjct: 4178 RLAGLAEAEREQVVLDLVRTEVAAVLGHAGAQSVGADDSFKDIGFDSLTAVELRNRLNSA 4237 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 G+ L AT FDYP P LA L Sbjct: 4238 VGMRLPATLIFDYPNPLTLAHFL 4260 Score = 76.3 bits (186), Expect = 5e-11 Identities = 40/83 (48%), Positives = 50/83 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL G + EQ +L +V E A VLG G +A + F + G SL+AVELR+RL T Sbjct: 2445 RLLGATPGEQGRILLDLVREQAATVLGHTGKGAFEADRTFRETGFDSLTAVELRHRLNTA 2504 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 TG+ L T FD+PTPT LA HL Sbjct: 2505 TGLRLPTTLVFDHPTPTALARHL 2527 Score = 76.3 bits (186), Expect = 5e-11 Identities = 49/132 (37%), Positives = 65/132 (49%), Gaps = 6/132 (4%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL AE++ VL +V AAVLG A + AF DAG SL++VELRNRL Sbjct: 5867 RLAGLPQAEREQVVLDLVRAEVAAVLGHASAQAVQPEHAFQDAGFDSLTSVELRNRLNAA 5926 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL--HHQNPTGATPELDRVDALTDLFLQTC----D 2135 TG+ L T FD+PTP L+ LL+ + A + D + C D Sbjct: 5927 TGLRLPVTMVFDHPTPVALSRFLLAETLGVQEQAEAAIAAVTGTDEAIAIVGMACRFPGD 5986 Query: 2136 AGRDDDGWQIVA 2147 +D W++VA Sbjct: 5987 VRSPEDLWRLVA 5998 Score = 69.3 bits (168), Expect = 6e-09 Identities = 38/83 (45%), Positives = 49/83 (59%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+ + +AE++ VL +V AA LG + AF D G SL+AVELRNRL Sbjct: 7575 RLEEMPEAEREKTVLDLVRAEVAAGLGHASDRTVRPEHAFQDLGFDSLTAVELRNRLNKA 7634 Query: 1070 TGVTLSATTAFDYPTPTQLADHL 1092 TG+ L AT FD+PTP LA H+ Sbjct: 7635 TGLRLPATLVFDHPTPALLARHV 7657 Score = 69.3 bits (168), Expect = 6e-09 Identities = 38/83 (45%), Positives = 49/83 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+ + +AE++ VL +V AA LG + AF D G SL+AVELRNRL Sbjct: 7575 RLEEMPEAEREKTVLDLVRAEVAAGLGHASDRTVRPEHAFQDLGFDSLTAVELRNRLNKA 7634 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 TG+ L AT FD+PTP LA H+ Sbjct: 7635 TGLRLPATLVFDHPTPALLARHV 7657 >tr|Q93H87|Q93H87_STRAW Tax_Id=33903 (pteA1)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 6048 Score = 1634 bits (4232), Expect = 0.0 Identities = 954/1926 (49%), Positives = 1167/1926 (60%), Gaps = 50/1926 (2%) Query: 85 SQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARR 144 S+ +A + C+ + + + IAVIG+ACR G W L+E AIT+ P R Sbjct: 4 SELNATGNRDCSA--SADSADGIAVIGLACRLPGAADPAA-FWRLLSEGADAITDVPPDR 60 Query: 145 L-GAAAADWLGDEQETIY-GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALE 202 GA AD ++ I G FL+ + FD FF + P EAA MDPQQRL+LE +W ALE Sbjct: 61 WDGAVVADASAPDRTGIRRGGFLDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALE 120 Query: 203 HAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDN-TGGSSSIIANRLSYFLDV 261 A + TL+ + TGVFVG DY L G TG SIIANR+SYFL + Sbjct: 121 DAHVRAATLRSTRTGVFVGAMWDDYATLHHRSGLTAISPHTVTGLHRSIIANRVSYFLGL 180 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 NGPSL +D+ SSSLV+ HLA +SL GE +A+ G N+ I PE G + G +SP G Sbjct: 181 NGPSLTVDSGQSSSLVSVHLACESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDG 240 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C FDARA+G VRGEG G+VVL+ L+ A G V V+ GSAVN DG +G+ P Sbjct: 241 RCFTFDARANGYVRGEGGGIVVLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQS 300 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSI 441 Q VL A + A ++PA++ YVE HGTGT VGD IEA ALG V G GR+ +PL +GS Sbjct: 301 GQEQVLRLAYERAGVNPADVGYVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSA 360 Query: 442 KPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAV 501 K N+GHLEGAAGI GL+K VL L +L S F PNP IP L L V E EW A Sbjct: 361 KTNVGHLEGAAGITGLLKAVLSLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAE 420 Query: 502 VGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLA--WVVSARTAAGVGAQA 559 GRP AGVSSFG GGTN H G G W +SA+TA+G+ AQA Sbjct: 421 DGRPLLAGVSSFGMGGTNCHIVLASGAAVEAGEGATAGGGAAPTFWPLSAKTASGLRAQA 480 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 LL A L DVG+SL T R+ FEHRAVVVG RD+ L L E+ G + Sbjct: 481 AALLAHTEAPLGLALPDVGWSLATGRTAFEHRAVVVGEVRDDFLRALRELSTGGIDAALT 540 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 +G A P G+ F+F GQG+Q GMGREL P LD L RPLREV++ Sbjct: 541 TGRAGPRGELAFLFSGQGSQRAGMGRELAESVPAFASALDEVCAHLDPLLPRPLREVMFA 600 Query: 680 ----ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXX 735 +A L+ T + Q +LFAVEVAL+RLLESW + P ++MGHS+GEL+AAHV+G Sbjct: 601 PVGTGEAAELDQTLYTQTSLFAVEVALFRLLESWDITPDVLMGHSIGELAAAHVAGVLSL 660 Query: 736 XXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQ---VSVAAVNGPGSVVLSGA 792 RGRLMQALP GG M AVQA E E+R +GE+ VS+AA+NGP SVV+SG Sbjct: 661 ADACALVAARGRLMQALPAGGAMIAVQAAEDEVRARIGERTDRVSIAALNGPDSVVVSGD 720 Query: 793 REAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVT 852 + + + D AA GR+ RL VSHAFHS MEPML +FR VA+ + P IP++SNVT Sbjct: 721 EDLATEIADAFAALGRKTSRLRVSHAFHSPHMEPMLAEFRNVAEGLTFHAPRIPIVSNVT 780 Query: 853 GQLVAEDYG----SADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL 908 G+L E G +A YWVRH+REAVRFAD V G ++E+GP G L S+ Sbjct: 781 GRLSEEPSGYEGCTAAYWVRHVREAVRFADGVARLDEQGVRTYLELGPGGVLASMARAGA 840 Query: 909 AQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQR--VGLPTYAFAH 966 S+ VP LR RPE DW ++ G G R V LPTYAF Sbjct: 841 DSESLF-VPALRTRRPEAQALLAAVASLHVHGVEPDWDALFGGGRGARRKVALPTYAFER 899 Query: 967 ERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAM 1026 +R+WL + RL GL+++E+ AVL M Sbjct: 900 QRYWLDGDTTSPVATTGWAPVAPQPDAIAETDSAPVGALGR--RLAGLAESERDEAVLDM 957 Query: 1027 VCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPT 1086 V H AAVLG A Q++ F D G SLS+VELRN+L TG+ L + FD+PTP Sbjct: 958 VRAHIAAVLGHAEARQVETEWTFKDLGFDSLSSVELRNQLSEATGLRLPSGLLFDHPTPA 1017 Query: 1087 QLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGD 1146 LA HL + A AAA T EPIAIV M CR PGGVSSP LW+L+ASGGD Sbjct: 1018 ALARHLAAQ-SLGGGDAAAAAPATVADPHEPIAIVAMSCRLPGGVSSPEDLWRLLASGGD 1076 Query: 1147 VIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQ 1206 I FP DRGWD+E L+DP+P GK+ TRHGGF+ + A+FD GFFGISP EA A+DPQQ Sbjct: 1077 GISGFPTDRGWDVETLYDPEPGTPGKSSTRHGGFLHEAAEFDAGFFGISPREAAAIDPQQ 1136 Query: 1207 RLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ----AQWYADTGHITSV 1262 RL+LET+WEA E AGIDP LRGS GVF+G YG + + Y TG TSV Sbjct: 1137 RLVLETAWEAFERAGIDPATLRGSRAGVFIGATAQDYGPRLHEPADGVEGYLLTGTTTSV 1196 Query: 1263 ASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIG 1322 ASGR++Y GL GPA++VDTACSSSLVALHLA SLR+GEC +ALAGG TV++TP +F+ Sbjct: 1197 ASGRVAYSFGLEGPAVTVDTACSSSLVALHLAVQSLRSGECTMALAGGVTVMSTPGMFVE 1256 Query: 1323 FSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDG 1382 FSRQRGL+ DGRCKAFA ADGTG++EG GML+++RLSDARR G VLA++ GSAVNQDG Sbjct: 1257 FSRQRGLSADGRCKAFAAGADGTGWAEGVGMLLVERLSDARRNGHQVLAVVRGSAVNQDG 1316 Query: 1383 ASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDH 1442 ASNGLTAP+GP+QQRV+ AL+ AG+ ADVD VEAHGTGT LGDPIEA+AL+A YG+ Sbjct: 1317 ASNGLTAPNGPSQQRVVRQALAAAGLAPADVDAVEAHGTGTLLGDPIEAEALIAAYGQGR 1376 Query: 1443 TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQ 1502 D PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP TLH+D+P+ HVDWS V+ Sbjct: 1377 DGDRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPTPHVDWSASGVR 1436 Query: 1503 LLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSAR 1562 LLTEA EWPA PRRA VSSFG+SGTNAH G + WVVSA+ Sbjct: 1437 LLTEAVEWPA-RDLPRRAAVSSFGISGTNAHVIVEQAATSEEPARGTAVAGPVPWVVSAK 1495 Query: 1563 TAAGVGAQAGRLLEFVRA----GRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGL 1618 + + QAGRLL F+ A G + DV SL T+R++ E RA VVG EL GL Sbjct: 1496 SDVALREQAGRLLSFLDAEGVGGAGVRPEDVALSLATSRAVLERRAAVVGGDLAELRQGL 1555 Query: 1619 AEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELD 1678 + G G G GG+ F+F GQG+Q +GMGREL A YP LD Sbjct: 1556 EALASGASGAAPVGGAV--GGRVGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVCAFLD 1613 Query: 1679 RHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSA 1738 + D+E LN T QPALFAVEVAL+RLLESWG+RP V GHSVGE++A Sbjct: 1614 APV---------DVDSEELNQTGTTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAA 1664 Query: 1739 AHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGS 1798 AHV+G R LMQALP GG M AVQA E E+ L + V +AAVNGP S Sbjct: 1665 AHVAGVLSLEDAAKLVSARAALMQALPDGGAMVAVQATEDEVLRHLTDGVGIAAVNGPRS 1724 Query: 1799 VVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIP 1858 VV+SGA +AV+ V + A +GR+ RL VSHAFHS LM+PMLE+F AV + IP Sbjct: 1725 VVVSGAEDAVTAVGEIFAGRGRKTSRLKVSHAFHSPLMDPMLEEFAAVVRGLTFSESRIP 1784 Query: 1859 VISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEE 1918 V+SN+TG+L AE Y + +YWVRH+REAVRFAD + G T FVEVGP G L++L + Sbjct: 1785 VVSNLTGRL-AEVY-TPEYWVRHVREAVRFADGIETLGELGVTTFVEVGPGGVLSALAQG 1842 Query: 1919 SLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFA 1977 +V VP LR DRPEP+ DW + G +RV LPTYAF Sbjct: 1843 CFDDGTDIVTVPVLRADRPEPYALVTAIGRLHTHGISPDWQVLFP--GARRVDLPTYAFQ 1900 Query: 1978 HERFWL 1983 ER+WL Sbjct: 1901 RERYWL 1906 Score = 996 bits (2574), Expect = 0.0 Identities = 539/981 (54%), Positives = 651/981 (66%), Gaps = 23/981 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL G + EQ +L +V E A VLG G +A + F + G SL+AVELR+RL T Sbjct: 2445 RLLGATPGEQGRILLDLVREQAATVLGHTGKGAFEADRTFRETGFDSLTAVELRHRLNTA 2504 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRI-DEPIAIVGMGCRYP 1128 TG+ L T FD+PTPT LA HL L ++ AAA T DEP+AIVGM CR P Sbjct: 2505 TGLRLPTTLVFDHPTPTALARHLGEELLGRHGLETAAAQATAAAAADEPLAIVGMSCRLP 2564 Query: 1129 GGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFD 1188 GGV SP LW+L++SG D + FP DRGWDI+ L+DPDPD GKTY+R GGF+ FD Sbjct: 2565 GGVQSPEDLWELLSSGRDAMSGFPTDRGWDIDALYDPDPDRPGKTYSREGGFIQGADRFD 2624 Query: 1189 PGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS 1248 G FGISP EALAMDPQQRLLLET+WEA E AGI ++R S TGVF+G G Y G Sbjct: 2625 AGLFGISPREALAMDPQQRLLLETAWEAFERAGIALASVRASRTGVFIGTNGQDYANGLR 2684 Query: 1249 QA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 A + YA TG SV SGRISY GL GPA++VDTACSSSLVALHLAA +LR+GEC Sbjct: 2685 NAPEEIEGYALTGKAASVVSGRISYTFGLEGPAVTVDTACSSSLVALHLAAQALRSGECS 2744 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 +AL GG TV+ TP +F+ FSRQRGL+ DGRCKAFA ADGTG+ EG G+L+++RLSDARR Sbjct: 2745 MALVGGVTVMTTPDLFVEFSRQRGLSPDGRCKAFAAGADGTGWGEGVGLLLVERLSDARR 2804 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 G VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+ AG+T ADVD VEAHGTGTR Sbjct: 2805 NGHQVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLTPADVDAVEAHGTGTR 2864 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG++H+ D P+WLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP T Sbjct: 2865 LGDPIEAQALLATYGQEHSDDRPVWLGSVKSNIGHTQAAAGVAGVIKMVLAMRHGVLPQT 2924 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH-XXXXXXXXXX 1543 LH+D+P+AHVDWS G V+LLTE +WP G PRRA VSSFG+ GTNAH Sbjct: 2925 LHVDEPTAHVDWSAGAVRLLTEPVQWPGTTG-PRRAAVSSFGIGGTNAHTIIEEAPAAAA 2983 Query: 1544 XXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHR 1603 P + WV+SA++ + AQA RLL F A ++ D G+S TTRS EHR Sbjct: 2984 AEPAREHRPVPVPWVLSAKSEVALRAQAERLLAF--ATDDVSPVDAGFSSATTRSALEHR 3041 Query: 1604 AVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGY 1663 A V+G+ EL AGL + G P V +G A K F+F GQG+Q LGMGREL A Y Sbjct: 3042 AAVIGSDPAELRAGLEALAAGEPAANVVAGRAHSADKVGFLFSGQGSQRLGMGRELYAAY 3101 Query: 1664 PXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGM 1723 P LD + DAE L+ T QPALFAVEVAL+RLLESWG+ Sbjct: 3102 PVFAAAYDEVCALLDATV---------DVDAETLHQTGSTQPALFAVEVALFRLLESWGI 3152 Query: 1724 RPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPL 1783 RP V GHSVGE++AAHV+G R LM+ALP GGVM AVQA E E+ P Sbjct: 3153 RPDYVAGHSVGEIAAAHVAGVLSLEDAAKLVSARAALMKALPAGGVMVAVQAAEDEMLPH 3212 Query: 1784 LGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQF 1843 L ++ +AA+NGP SVV+SGA +AV+ + + AAQGR+ RL VSHAFHS LM+PMLE+F Sbjct: 3213 LIDRAGIAAINGPRSVVISGAEDAVTAIAEVFAAQGRKTSRLKVSHAFHSPLMDPMLEEF 3272 Query: 1844 RAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRF 1903 V + P IPV+SN+TG+L E Y + +YWVRH+REAVRFAD V H G T F Sbjct: 3273 AEVVRGLTFSEPWIPVVSNLTGRL-TESY-TPEYWVRHVREAVRFADGVLTLHELGVTTF 3330 Query: 1904 VEVGPAGGLTSLIEESLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLA 1962 VE+GP G L++L++ L +V +P LR DRPEP DW + Sbjct: 3331 VEIGPGGVLSALVQGCLDDGTDIVTIPALRADRPEPQALTTAYAQLHVSGAEVDWHAFFP 3390 Query: 1963 GCGGQRVGLPTYAFAHERFWL 1983 G +RV LPTYAF ER+WL Sbjct: 3391 --GARRVELPTYAFQRERYWL 3409 Score = 987 bits (2551), Expect = 0.0 Identities = 541/985 (54%), Positives = 652/985 (66%), Gaps = 30/985 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL++AE++ VL +V AAVLG GA + A +F D G SL+AVELRNRL + Sbjct: 4178 RLAGLAEAEREQVVLDLVRTEVAAVLGHAGAQSVGADDSFKDIGFDSLTAVELRNRLNSA 4237 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLH--HQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 G+ L AT FDYP P LA L + P DEPIAIVGM CRY Sbjct: 4238 VGMRLPATLIFDYPNPLTLAHFLTGEAAGGEAATAVPTTLSTATGTADEPIAIVGMACRY 4297 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGGV SP LWQLV SG D + FP RGWD+E+L+DP+PD G +YTR GGF+ D ADF Sbjct: 4298 PGGVQSPEDLWQLVFSGRDAVSGFPEGRGWDVEQLYDPNPDQWGTSYTREGGFLHDAADF 4357 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--L 1245 D FFGISP EALAMDPQQRLLLETSWEA E AGIDP +RGS TGVF G+ YG + Sbjct: 4358 DAEFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATVRGSRTGVFAGVMYHDYGGRV 4417 Query: 1246 GTSQA--QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGEC 1303 TS + Y G S+ASGR+SY GL GPA++VDTACSSSLVALHLAA +LR+GEC Sbjct: 4418 HTSPPGLEGYLVNGSAGSIASGRVSYTFGLEGPAVTVDTACSSSLVALHLAAQALRSGEC 4477 Query: 1304 DLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDAR 1363 +AL GG TV+A PS+F+ FSRQRGL+ DGRCKAF ADGTG++EG GML+++RLSDAR Sbjct: 4478 SMALVGGVTVMAGPSVFVEFSRQRGLSADGRCKAFGAGADGTGWAEGVGMLLVERLSDAR 4537 Query: 1364 RAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGT 1423 R G VLA++ G+AVNQDGASNGLTAP+GP+QQRVI AL++AG++ +VD VEAHGTGT Sbjct: 4538 RNGHKVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAGLSSDEVDAVEAHGTGT 4597 Query: 1424 RLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPA 1483 RLGDPIEAQAL+ATYG++ + D PLWLGS+KSN+GHSQAAAGV GVIKMV AM+H +LP Sbjct: 4598 RLGDPIEAQALIATYGQERSEDRPLWLGSLKSNIGHSQAAAGVGGVIKMVMAMQHGVLPQ 4657 Query: 1484 TLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXX 1543 TLH+D+P+ HVDWS G VQLLTEA EWPA G PRRA VSSFGVSGTNAH Sbjct: 4658 TLHVDEPTPHVDWSAGAVQLLTEAVEWPASDG-PRRAAVSSFGVSGTNAHVIVEQAATSE 4716 Query: 1544 XXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRA----GRELDAGDVGYSLVTTRSL 1599 G + WV+SA++ A + QAGRLL F+ A G + DV YSL T+R++ Sbjct: 4717 VTARGTAVAGPVPWVLSAKSDAALREQAGRLLSFLDAEGVGGAGVRPEDVAYSLATSRAV 4776 Query: 1600 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 1659 E RA VVG E GL +V G VG A GG+ F+F GQG+Q +GMGREL Sbjct: 4777 LECRAAVVGEELGEFRQGLEGIVSGAAPVGGA-----VGGRVGFLFSGQGSQRIGMGREL 4831 Query: 1660 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 1719 A YP LD + DAE L+ T QPALFAVEVAL+RLLE Sbjct: 4832 YAAYPVFAAAYDEVCALLDATV---------DVDAETLHQTGSTQPALFAVEVALFRLLE 4882 Query: 1720 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 1779 SWG+RP V GHSVGE++AAHV+G R LMQALP GG M A+QA E E Sbjct: 4883 SWGIRPDYVAGHSVGEIAAAHVAGVLSLEDAAKLVSARAALMQALPAGGAMVAIQATEAE 4942 Query: 1780 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 1839 + P L V +AA+NGP SVVLSG+ +AV + + A QGR+ RL VSHAFHS LM+PM Sbjct: 4943 VLPHLTHGVGLAAINGPRSVVLSGSEDAVLDIAEVFAQQGRKTSRLKVSHAFHSPLMDPM 5002 Query: 1840 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 1899 LE+F V + P IPV+SN+TG+L AE Y +YWVRH+REAVRFAD + H G Sbjct: 5003 LEEFAEVVRGLTFSEPRIPVVSNLTGRL-AEVY-IPEYWVRHVREAVRFADGLHTLHELG 5060 Query: 1900 ATRFVEVGPAGGLTSLIEESLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWA 1958 T FVE+GP G L++L++ L +V VP LR DRPEP+ +W Sbjct: 5061 VTMFVEIGPGGVLSALVQGCLDDGTHIVTVPALRADRPEPYALVTAVGQLHTHGISPEWQ 5120 Query: 1959 SVLAGCGGQRVGLPTYAFAHERFWL 1983 ++ G +RV LPTYAF ER+WL Sbjct: 5121 ALFP--GARRVDLPTYAFQRERYWL 5143 Score = 743 bits (1919), Expect = 0.0 Identities = 442/1007 (43%), Positives = 573/1007 (56%), Gaps = 27/1007 (2%) Query: 1118 IAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRH 1177 IA++G+ CR PG + PA W+L++ G D I + PPDR WD + D A +T R Sbjct: 24 IAVIGLACRLPGA-ADPAAFWRLLSEGADAITDVPPDR-WDGAVV--ADASAPDRTGIRR 79 Query: 1178 GGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVG 1237 GGF+ + DFD GFFG+SP EA AMDPQQRL+LE +WEALEDA + LR + TGVFVG Sbjct: 80 GGFLDSIGDFDAGFFGLSPKEAAAMDPQQRLVLELAWEALEDAHVRAATLRSTRTGVFVG 139 Query: 1238 IYGDGYGL-----GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 D Y G + + TG S+ + R+SY LGL GP+++VD+ SSSLV++H Sbjct: 140 AMWDDYATLHHRSGLTAISPHTVTGLHRSIIANRVSYFLGLNGPSLTVDSGQSSSLVSVH 199 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 LA SLR GE +ALAGG + P +G ++ GL+ DGRC F A+G EG G Sbjct: 200 LACESLRKGESTIALAGGVNLNIVPESALGAAKFGGLSPDGRCFTFDARANGYVRGEGGG 259 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 ++VL+ L+ A G PV ++ GSAVN DG +GLT P Q++V+ A AG+ AD Sbjct: 260 IVVLKPLARAVADGDPVYCVIRGSAVNNDGGGDGLTVPLQSGQEQVLRLAYERAGVNPAD 319 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKM 1472 V VE HGTGT++GDPIEA AL A G P PL +GS K+N+GH + AAG+ G++K Sbjct: 320 VGYVELHGTGTKVGDPIEAAALGAVLGTGREPGRPLRVGSAKTNVGHLEGAAGITGLLKA 379 Query: 1473 VEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNA 1532 V ++ H+ LPA+L+ P+ + +++ TE EW A GRP AGVSSFG+ GTN Sbjct: 380 VLSLNHRELPASLNFGTPNPAIPLDRLNLRVQTEHSEWAAEDGRPLLAGVSSFGMGGTNC 439 Query: 1533 HXXXXXXXXXXXXXXXXXGPGVLA--WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVG 1590 H G G W +SA+TA+G+ AQA LL A L DVG Sbjct: 440 HIVLASGAAVEAGEGATAGGGAAPTFWPLSAKTASGLRAQAAALLAHTEAPLGLALPDVG 499 Query: 1591 YSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGA 1650 +SL T R+ FEHRAVVVG RD+ L L E+ G + +G A P G+ F+F GQG+ Sbjct: 500 WSLATGRTAFEHRAVVVGEVRDDFLRALRELSTGGIDAALTTGRAGPRGELAFLFSGQGS 559 Query: 1651 QWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG----ADAELLNTTEFAQPA 1706 Q GMGREL P LD L RPLREV++ +A L+ T + Q + Sbjct: 560 QRAGMGRELAESVPAFASALDEVCAHLDPLLPRPLREVMFAPVGTGEAAELDQTLYTQTS 619 Query: 1707 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 1766 LFAVEVAL+RLLESW + P ++MGHS+GEL+AAHV+G RGRLMQALP Sbjct: 620 LFAVEVALFRLLESWDITPDVLMGHSIGELAAAHVAGVLSLADACALVAARGRLMQALPA 679 Query: 1767 GGVMYAVQAGEQELRPLLGEQ---VSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 1823 GG M AVQA E E+R +GE+ VS+AA+NGP SVV+SG + + + D AA GR+ Sbjct: 680 GGAMIAVQAAEDEVRARIGERTDRVSIAALNGPDSVVVSGDEDLATEIADAFAALGRKTS 739 Query: 1824 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYG----SADYWV 1879 RL VSHAFHS MEPML +FR VA+ + P IP++SNVTG+L E G +A YWV Sbjct: 740 RLRVSHAFHSPHMEPMLAEFRNVAEGLTFHAPRIPIVSNVTGRLSEEPSGYEGCTAAYWV 799 Query: 1880 RHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPF 1939 RH+REAVRFAD V G ++E+GP G L S+ S+ VP LR RPE Sbjct: 800 RHVREAVRFADGVARLDEQGVRTYLELGPGGVLASMARAGADSESLF-VPALRTRRPEAQ 858 Query: 1940 XXXXXXXXXXXXXXXXDWASVLAGCGGQR--VGLPTYAFAHERFWLADRFXXXXXXXXXX 1997 DW ++ G G R V LPTYAF +R+WL Sbjct: 859 ALLAAVASLHVHGVEPDWDALFGGGRGARRKVALPTYAFERQRYWLDGDTTSPVATTGWA 918 Query: 1998 XLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDA 2057 + RL GL+++E+ AVL MV H AAVLG A Q++ Sbjct: 919 PVAPQPDAIAETDSAPVGALGR--RLAGLAESERDEAVLDMVRAHIAAVLGHAEARQVET 976 Query: 2058 GQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHL 2104 F D G SLS+VELRN+L TG+ L + FD+PTP LA HL Sbjct: 977 EWTFKDLGFDSLSSVELRNQLSEATGLRLPSGLLFDHPTPAALARHL 1023 Score = 707 bits (1825), Expect = 0.0 Identities = 409/950 (43%), Positives = 555/950 (58%), Gaps = 32/950 (3%) Query: 33 DLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPS----AHDVIKSVLGGDGSQRS 88 D R+ G S+ + + L+ G+ +P V+D+P+ A + + +LG G + + Sbjct: 2481 DRTFRETGFDSLTAVELRHRLNTATGLRLPTTLVFDHPTPTALARHLGEELLGRHGLETA 2540 Query: 89 ADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAA 148 A T A +EP+A++GM+CR G V LW+ L+ + A++ +P R Sbjct: 2541 AAQATAAAA-----ADEPLAIVGMSCRLPGGVQSPEDLWELLSSGRDAMSGFPTDRGWDI 2595 Query: 149 AADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEH 203 A + D + G F++ + FD F I P EA MDPQQRLLLET+W A E Sbjct: 2596 DALYDPDPDRPGKTYSREGGFIQGADRFDAGLFGISPREALAMDPQQRLLLETAWEAFER 2655 Query: 204 AGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNG 263 AGI +++ S TGVF+G + DY L + + TG ++S+++ R+SY + G Sbjct: 2656 AGIALASVRASRTGVFIGTNGQDYANGLRNAPEEIEGYALTGKAASVVSGRISYTFGLEG 2715 Query: 264 PSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSC 323 P++ +DTACSSSLVA HLA ++L SGEC +A+V G V+ +P+++ F +SP G C Sbjct: 2716 PAVTVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMTTPDLFVEFSRQRGLSPDGRC 2775 Query: 324 RAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQ 383 +AF A ADG GEG G++++ERLSDARR G VLA++ GSAVNQDG SNG+ APN +Q Sbjct: 2776 KAFAAGADGTGWGEGVGLLLVERLSDARRNGHQVLALVRGSAVNQDGASNGLTAPNGPSQ 2835 Query: 384 ISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKP 443 V+ A A + PA++D VEAHGTGT +GD IEA AL +G+ +P+ +GS+K Sbjct: 2836 QRVIRQALASAGLTPADVDAVEAHGTGTRLGDPIEAQALLATYGQEHSDDRPVWLGSVKS 2895 Query: 444 NIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVG 503 NIGH + AAG+AG+IK VL ++ G L + + P ++ ++ + ++ E +WP G Sbjct: 2896 NIGHTQAAAGVAGVIKMVLAMRHGVLPQTLHVDEPTAHVDWSAGAVRLLTEPVQWPGTTG 2955 Query: 504 RPRRAGVSSFGFGGTNAH-XXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRL 562 PRRA VSSFG GGTNAH P + WV+SA++ + AQA RL Sbjct: 2956 -PRRAAVSSFGIGGTNAHTIIEEAPAAAAAEPAREHRPVPVPWVLSAKSEVALRAQAERL 3014 Query: 563 LEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGV 622 L F A ++ D G+S TTRS EHRA V+G+ EL AGL + G P V +G Sbjct: 3015 LAF--ATDDVSPVDAGFSSATTRSALEHRAAVIGSDPAELRAGLEALAAGEPAANVVAGR 3072 Query: 623 AMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADA 682 A K F+F GQG+Q LGMGREL A YP LD + DA Sbjct: 3073 AHSADKVGFLFSGQGSQRLGMGRELYAAYPVFAAAYDEVCALLDATV---------DVDA 3123 Query: 683 ELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXX 742 E L+ T QPALFAVEVAL+RLLESWG+RP V GHSVGE++AAHV+G Sbjct: 3124 ETLHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVGEIAAAHVAGVLSLEDAAKLV 3183 Query: 743 XMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDR 802 R LM+ALP GGVM AVQA E E+ P L ++ +AA+NGP SVV+SGA +AV+ + + Sbjct: 3184 SARAALMKALPAGGVMVAVQAAEDEMLPHLIDRAGIAAINGPRSVVISGAEDAVTAIAEV 3243 Query: 803 LAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGS 862 AAQGR+ RL VSHAFHS LM+PMLE+F V + P IPV+SN+TG+L E Y + Sbjct: 3244 FAAQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSEPWIPVVSNLTGRL-TESY-T 3301 Query: 863 ADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQ-VSVVAVPTLRK 921 +YWVRH+REAVRFAD V H G T FVE+GP G L++L++ L +V +P LR Sbjct: 3302 PEYWVRHVREAVRFADGVLTLHELGVTTFVEIGPGGVLSALVQGCLDDGTDIVTIPALRA 3361 Query: 922 DRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 DRPEP DW + G +RV LPTYAF ER+WL Sbjct: 3362 DRPEPQALTTAYAQLHVSGAEVDWHAFFP--GARRVELPTYAFQRERYWL 3409 Score = 697 bits (1798), Expect = 0.0 Identities = 422/970 (43%), Positives = 551/970 (56%), Gaps = 42/970 (4%) Query: 19 IAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIK 77 +AA G A+ V D +D+G S+ + + L+ +G+ +P ++D P+ + Sbjct: 4199 VAAVLGHAGAQSVGADDSFKDIGFDSLTAVELRNRLNSAVGMRLPATLIFDYPNPLTLAH 4258 Query: 78 SVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAI 137 + G +A + G +EPIA++GMACR+ G V LW + + A+ Sbjct: 4259 FLTGEAAGGEAATAVPTTLSTATGTADEPIAIVGMACRYPGGVQSPEDLWQLVFSGRDAV 4318 Query: 138 TEYPARRLGAAAA--DWLGDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRL 192 + +P R D D+ T Y G FL D FD +FF I P EA MDPQQRL Sbjct: 4319 SGFPEGRGWDVEQLYDPNPDQWGTSYTREGGFLHDAADFDAEFFGISPREALAMDPQQRL 4378 Query: 193 LLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDN------TGG 246 LLETSW A E AGI P T++ S TGVF GV DY GGR T G Sbjct: 4379 LLETSWEAFERAGIDPATVRGSRTGVFAGVMYHDY------GGRVHTSPPGLEGYLVNGS 4432 Query: 247 SSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPE 306 + SI + R+SY + GP++ +DTACSSSLVA HLA ++L SGEC +A+V G V+ P Sbjct: 4433 AGSIASGRVSYTFGLEGPAVTVDTACSSSLVALHLAAQALRSGECSMALVGGVTVMAGPS 4492 Query: 307 VWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAV 366 V+ F +S G C+AF A ADG EG G++++ERLSDARR G VLAV+ G+AV Sbjct: 4493 VFVEFSRQRGLSADGRCKAFGAGADGTGWAEGVGMLLVERLSDARRNGHKVLAVVRGTAV 4552 Query: 367 NQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVF 426 NQDG SNG+ APN +Q V+ A A + E+D VEAHGTGT +GD IEA AL + Sbjct: 4553 NQDGASNGLTAPNGPSQQRVIRQALANAGLSSDEVDAVEAHGTGTRLGDPIEAQALIATY 4612 Query: 427 GRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAE 486 G+ R +PL +GS+K NIGH + AAG+ G+IK V+ +Q G L + + P P++ ++ Sbjct: 4613 GQERSEDRPLWLGSLKSNIGHSQAAAGVGGVIKMVMAMQHGVLPQTLHVDEPTPHVDWSA 4672 Query: 487 LGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWV 546 + ++ E EWPA G PRRA VSSFG GTNAH G + WV Sbjct: 4673 GAVQLLTEAVEWPASDG-PRRAAVSSFGVSGTNAHVIVEQAATSEVTARGTAVAGPVPWV 4731 Query: 547 VSARTAAGVGAQAGRLLEFVRA----GRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDEL 602 +SA++ A + QAGRLL F+ A G + DV YSL T+R++ E RA VVG E Sbjct: 4732 LSAKSDAALREQAGRLLSFLDAEGVGGAGVRPEDVAYSLATSRAVLECRAAVVGEELGEF 4791 Query: 603 LAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXX 662 GL +V G VG A GG+ F+F GQG+Q +GMGREL A YP Sbjct: 4792 RQGLEGIVSGAAPVGGA-----VGGRVGFLFSGQGSQRIGMGRELYAAYPVFAAAYDEVC 4846 Query: 663 XELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVG 722 LD + DAE L+ T QPALFAVEVAL+RLLESWG+RP V GHSVG Sbjct: 4847 ALLDATV---------DVDAETLHQTGSTQPALFAVEVALFRLLESWGIRPDYVAGHSVG 4897 Query: 723 ELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVN 782 E++AAHV+G R LMQALP GG M A+QA E E+ P L V +AA+N Sbjct: 4898 EIAAAHVAGVLSLEDAAKLVSARAALMQALPAGGAMVAIQATEAEVLPHLTHGVGLAAIN 4957 Query: 783 GPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGR 842 GP SVVLSG+ +AV + + A QGR+ RL VSHAFHS LM+PMLE+F V + Sbjct: 4958 GPRSVVLSGSEDAVLDIAEVFAQQGRKTSRLKVSHAFHSPLMDPMLEEFAEVVRGLTFSE 5017 Query: 843 PAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTS 902 P IPV+SN+TG+L AE Y +YWVRH+REAVRFAD + H G T FVE+GP G L++ Sbjct: 5018 PRIPVVSNLTGRL-AEVY-IPEYWVRHVREAVRFADGLHTLHELGVTMFVEIGPGGVLSA 5075 Query: 903 LIEESLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPT 961 L++ L +V VP LR DRPEP+ +W ++ G +RV LPT Sbjct: 5076 LVQGCLDDGTHIVTVPALRADRPEPYALVTAVGQLHTHGISPEWQALFP--GARRVDLPT 5133 Query: 962 YAFAHERFWL 971 YAF ER+WL Sbjct: 5134 YAFQRERYWL 5143 Score = 690 bits (1780), Expect = 0.0 Identities = 420/988 (42%), Positives = 559/988 (56%), Gaps = 58/988 (5%) Query: 9 DALQEWFTHYIAARTG-CDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVW 67 +A+ + +IAA G ++ +V + +DLG S+ + + +LS+ G+ +P ++ Sbjct: 952 EAVLDMVRAHIAAVLGHAEARQVETEWTFKDLGFDSLSSVELRNQLSEATGLRLPSGLLF 1011 Query: 68 DNPSA-----HDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHG 122 D+P+ H +S+ GGD + A +EPIA++ M+CR G V Sbjct: 1012 DHPTPAALARHLAAQSLGGGDAA--------AAAPATVADPHEPIAIVAMSCRLPGGVSS 1063 Query: 123 VGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIY--------------GCFLEDV 168 LW LA I+ +P R G + ET+Y G FL + Sbjct: 1064 PEDLWRLLASGGDGISGFPTDR---------GWDVETLYDPEPGTPGKSSTRHGGFLHEA 1114 Query: 169 EGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYV 228 FD FF I P EAA +DPQQRL+LET+W A E AGI P TL+ S GVF+G ++ DY Sbjct: 1115 AEFDAGFFGISPREAAAIDPQQRLVLETAWEAFERAGIDPATLRGSRAGVFIGATAQDYG 1174 Query: 229 RLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLAS 288 L + TG ++S+ + R++Y + GP++ +DTACSSSLVA HLA +SL S Sbjct: 1175 PRLHEPADGVEGYLLTGTTTSVASGRVAYSFGLEGPAVTVDTACSSSLVALHLAVQSLRS 1234 Query: 289 GECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLS 348 GEC +A+ G V+ +P ++ F +S G C+AF A ADG EG G++++ERLS Sbjct: 1235 GECTMALAGGVTVMSTPGMFVEFSRQRGLSADGRCKAFAAGADGTGWAEGVGMLLVERLS 1294 Query: 349 DARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHG 408 DARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ A A + PA++D VEAHG Sbjct: 1295 DARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRQALAAAGLAPADVDAVEAHG 1354 Query: 409 TGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQ 468 TGT +GD IEA AL +G+GR +PL +GS+K NIGH + AAG+AG+IK V+ ++ G Sbjct: 1355 TGTLLGDPIEAEALIAAYGQGRDGDRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGV 1414 Query: 469 LLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXX 528 L + + P P++ ++ G+ ++ E EWPA PRRA VSSFG GTNAH Sbjct: 1415 LPRTLHVDEPTPHVDWSASGVRLLTEAVEWPA-RDLPRRAAVSSFGISGTNAHVIVEQAA 1473 Query: 529 XXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRA----GRELDAGDVGYSLVTT 584 G + WVVSA++ + QAGRLL F+ A G + DV SL T+ Sbjct: 1474 TSEEPARGTAVAGPVPWVVSAKSDVALREQAGRLLSFLDAEGVGGAGVRPEDVALSLATS 1533 Query: 585 RSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMG 644 R++ E RA VVG EL GL + G G G GG+ F+F GQG+Q +GMG Sbjct: 1534 RAVLERRAAVVGGDLAELRQGLEALASGASGAAPVGGAV--GGRVGFLFSGQGSQRIGMG 1591 Query: 645 RELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYR 704 REL A YP LD + D+E LN T QPALFAVEVAL+R Sbjct: 1592 RELYAAYPVFAAAYDEVCAFLDAPV---------DVDSEELNQTGTTQPALFAVEVALFR 1642 Query: 705 LLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAG 764 LLESWG+RP V GHSVGE++AAHV+G R LMQALP GG M AVQA Sbjct: 1643 LLESWGIRPDYVAGHSVGEIAAAHVAGVLSLEDAAKLVSARAALMQALPDGGAMVAVQAT 1702 Query: 765 EQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLM 824 E E+ L + V +AAVNGP SVV+SGA +AV+ V + A +GR+ RL VSHAFHS LM Sbjct: 1703 EDEVLRHLTDGVGIAAVNGPRSVVVSGAEDAVTAVGEIFAGRGRKTSRLKVSHAFHSPLM 1762 Query: 825 EPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAH 884 +PMLE+F AV + IPV+SN+TG+L AE Y + +YWVRH+REAVRFAD + Sbjct: 1763 DPMLEEFAAVVRGLTFSESRIPVVSNLTGRL-AEVY-TPEYWVRHVREAVRFADGIETLG 1820 Query: 885 SAGATRFVEVGPAGGLTSLIEESLAQ-VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXX 943 G T FVEVGP G L++L + +V VP LR DRPEP+ Sbjct: 1821 ELGVTTFVEVGPGGVLSALAQGCFDDGTDIVTVPVLRADRPEPYALVTAIGRLHTHGISP 1880 Query: 944 DWASVLAGCGGQRVGLPTYAFAHERFWL 971 DW + G +RV LPTYAF ER+WL Sbjct: 1881 DWQVLFP--GARRVDLPTYAFQRERYWL 1906 Score = 78.6 bits (192), Expect = 1e-11 Identities = 42/83 (50%), Positives = 52/83 (62%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL++AE++ VL +V AAVLG GA + A +F D G SL+AVELRNRL + Sbjct: 4178 RLAGLAEAEREQVVLDLVRTEVAAVLGHAGAQSVGADDSFKDIGFDSLTAVELRNRLNSA 4237 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 G+ L AT FDYP P LA L Sbjct: 4238 VGMRLPATLIFDYPNPLTLAHFL 4260 Score = 76.3 bits (186), Expect = 5e-11 Identities = 40/83 (48%), Positives = 50/83 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL G + EQ +L +V E A VLG G +A + F + G SL+AVELR+RL T Sbjct: 2445 RLLGATPGEQGRILLDLVREQAATVLGHTGKGAFEADRTFRETGFDSLTAVELRHRLNTA 2504 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 TG+ L T FD+PTPT LA HL Sbjct: 2505 TGLRLPTTLVFDHPTPTALARHL 2527 Score = 69.3 bits (168), Expect = 6e-09 Identities = 38/83 (45%), Positives = 49/83 (59%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+ + +AE++ VL +V AA LG + AF D G SL+AVELRNRL Sbjct: 5877 RLEEMPEAEREKTVLDLVRAEVAAGLGHASDRTVRPEHAFQDLGFDSLTAVELRNRLNKA 5936 Query: 1070 TGVTLSATTAFDYPTPTQLADHL 1092 TG+ L AT FD+PTP LA H+ Sbjct: 5937 TGLRLPATLVFDHPTPALLARHV 5959 Score = 69.3 bits (168), Expect = 6e-09 Identities = 38/83 (45%), Positives = 49/83 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+ + +AE++ VL +V AA LG + AF D G SL+AVELRNRL Sbjct: 5877 RLEEMPEAEREKTVLDLVRAEVAAGLGHASDRTVRPEHAFQDLGFDSLTAVELRNRLNKA 5936 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 TG+ L AT FD+PTP LA H+ Sbjct: 5937 TGLRLPATLVFDHPTPALLARHV 5959 >tr|Q8CJN6|Q8CJN6_STRCO Tax_Id=1902 SubName: Full=Putative type I polyketide synthase;[Streptomyces coelicolor] Length = 4557 Score = 1537 bits (3980), Expect = 0.0 Identities = 918/1907 (48%), Positives = 1122/1907 (58%), Gaps = 55/1907 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCF 164 E IAV+G++CR G W+ L A+TE P R A G G F Sbjct: 19 ERIAVVGLSCRLPGAADPAA-FWELLHSGSDAVTEVPPGRWDVPADAAPGSGSGGRRGAF 77 Query: 165 LEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSS 224 L+ V+ FD FF I P EAA MDPQQRL+LE +W ALE A I+P +L+ S T VFVG Sbjct: 78 LDGVDRFDAGFFGISPREAAAMDPQQRLVLELTWEALEDAAIVPASLRGSRTAVFVGTLR 137 Query: 225 TDYVRLLFPGGRKPTIWDNTGG-SSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLAR 283 DY LL+ G + G + +IA R+SY L + GPSL +D+A SSSLVA HLA Sbjct: 138 DDYTNLLYQYGDEAVTQHTMAGVNRGVIAGRVSYHLGLRGPSLTVDSAQSSSLVAVHLAC 197 Query: 284 KSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVV 343 +SL SGE AVVAG N+ + E + G +SP G FDARA+G V GEG GVVV Sbjct: 198 ESLRSGESTTAVVAGVNLNLLAENATTEERFGALSPDGVSYTFDARANGFVPGEGGGVVV 257 Query: 344 LERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAE-ID 402 L+ LS A G + V+ G+AVN DG ++G+ P+ AQ ++ A + + + P E + Sbjct: 258 LKPLSAALADGNRIHGVIRGTAVNNDGAADGLTVPSGTAQEQLIREAHRRSALGPGERVQ 317 Query: 403 YVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAGLIKTV 461 YVE HGTGT VGD +EA ALG G R A PL +GS+K NIGHLEGAAG+AGLIKT+ Sbjct: 318 YVELHGTGTPVGDPVEAAALGAALGAERGDADGPLRVGSVKTNIGHLEGAAGMAGLIKTL 377 Query: 462 LMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH 521 L + +L S F NP IP AELGL V E WP RP AGVSSFG GGTNAH Sbjct: 378 LAITHRELPASLNFRTANPAIPLAELGLEVQRELSAWPRP-DRPLVAGVSSFGMGGTNAH 436 Query: 522 XXXXXXXXXXXXXXXXXG---PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVG 578 G P L+WVV+A + + QA RL EF A D D G Sbjct: 437 VVVGEPPLPAAEPDTLTGSAAPSSLSWVVTANSEEALRGQAARLAEFAGAENAPDPRDTG 496 Query: 579 YSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGA 638 YSL T R++FEHRAVVVGA LL G+ + EGRPG GV G G T +F GQGA Sbjct: 497 YSLATDRTVFEHRAVVVGADGAALLDGVRALAEGRPGAGVVRGRG-EAGATALLFTGQGA 555 Query: 639 QWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAV 698 Q GMG+EL A +P LD L +PL EV+ A E L+ T QPALFA+ Sbjct: 556 QRPGMGQELYAAHPVFADAFDAVAERLDPMLKQPLWEVI--ASGEGLDETGRTQPALFAI 613 Query: 699 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 758 EVAL+RLLESWG+RPG + GHS+GEL+AAHV+G R RLMQALP GG M Sbjct: 614 EVALFRLLESWGVRPGFLAGHSIGELAAAHVAGVLSLDDAARLVAARARLMQALPAGGAM 673 Query: 759 YAVQAGEQELRPLLG---EQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 815 AV+A E+E+ P L ++S+AAVNGP SVV+SG +A V RLA GRR +RL V Sbjct: 674 IAVEATEEEVLPHLEGLEARLSLAAVNGPASVVISGEADAAEDVAARLAEAGRRTKRLTV 733 Query: 816 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVA-EDYGSADYWVRHIREAV 874 SHAFHS LM+ ML++F VA E+ P IPV+S +TG L + +D + YW +R AV Sbjct: 734 SHAFHSPLMDGMLKEFHKVAKELTYHAPRIPVVSTLTGALASGDDLRTPCYWTDQVRHAV 793 Query: 875 RFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXX 934 RFAD+V GAT +EVGP L+SL + A PTLR RPE Sbjct: 794 RFADAVRTLGELGATVLLEVGPDAVLSSLAD---------ATPTLRAGRPETRTLLTAVA 844 Query: 935 XXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXX 994 DW +V A GG+ V LPTYAF R W + Sbjct: 845 TAFVRGADVDWRAVHADAGGRSVPLPTYAFQRRRHWF-----DAAARKETRAIAPAADEV 899 Query: 995 XXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGL 1054 R + L AE +V H AVL +LD F G Sbjct: 900 RSPAAASGVPSVPAGRAERLRYAED------LVTSHVTAVLEYGDGERLDPRVPFQKLGF 953 Query: 1055 TSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTR-VR 1113 TSL ELR L TG+ L + FD+PTP +L L + L A R Sbjct: 954 TSLMTTELRAALAEATGLALPGSLLFDHPTPRELTAFLATRLADTTDEPEAGEEFIRPAD 1013 Query: 1114 IDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKT 1173 EPIAIVGM CR+PGG++SPAQLW+LV+ GGD I EFP +RGW + L+D DPD G++ Sbjct: 1014 AGEPIAIVGMACRFPGGITSPAQLWKLVSEGGDAITEFPVNRGWP-DDLYDADPDRPGRS 1072 Query: 1174 YTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTG 1233 RHGGF+ D +FD FFGISP EALAMDPQQRLLLE++WEA+E AGIDP LRGS TG Sbjct: 1073 AVRHGGFLHDAGEFDADFFGISPREALAMDPQQRLLLESAWEAVERAGIDPDTLRGSRTG 1132 Query: 1234 VFVGIYGDGYGLGTSQA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLV 1289 VFVG YG +A Q TG TSV SGRI+Y LGL GPA++ DTACSSSLV Sbjct: 1133 VFVGATALEYGPRMHEAPESVQGSVLTGSTTSVMSGRIAYQLGLLGPAVTTDTACSSSLV 1192 Query: 1290 ALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSE 1349 ALHLA SLR+GE LALAGG+TV+++P +F+ FSRQRGLA DGRCK+FA ADGTG+SE Sbjct: 1193 ALHLAIRSLRSGETSLALAGGATVMSSPGMFVEFSRQRGLAPDGRCKSFAAGADGTGWSE 1252 Query: 1350 GAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGIT 1409 G G+L+++RLSDARR G VLA++ GSAVNQDGASNGLTAP+G +QQRV+ AL+D+G+ Sbjct: 1253 GVGLLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGLSQQRVVRQALADSGLA 1312 Query: 1410 GADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGV 1469 +VD VEAHGTGTRLGDPIEA+AL+ATYG P++LGS+KSN+GH+QAAAGV GV Sbjct: 1313 ATEVDAVEAHGTGTRLGDPIEAEALMATYGTGRDGLPPVYLGSLKSNIGHAQAAAGVGGV 1372 Query: 1470 IKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSG 1529 IKMVEA+RH +LP TLH+D+PS VDW+ G ++LLT R WP GRPRRA VSSFG+SG Sbjct: 1373 IKMVEAIRHGVLPRTLHVDEPSPRVDWNAGALELLTGERAWPD-TGRPRRAAVSSFGISG 1431 Query: 1530 TNAH---XXXXXXXXXXXXXXXXXGPGVLA-WVVSARTAAGVGAQAGRLLEFVRAGRELD 1585 TNAH P V A W++SAR + AQA RL + R + Sbjct: 1432 TNAHVVLEQAPDAPPPSAAPPATQAPAVPAPWLLSARDPDTLRAQAERLRAYADGDRAPE 1491 Query: 1586 AGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVF 1645 +G +L TTR+ FE RAVV+ R LAGL ++ G GV +G A G+T F+F Sbjct: 1492 PAAIGRALATTRTAFEQRAVVLAEDRAGYLAGLDALIRGADAPGVVTGSARSAGRTAFLF 1551 Query: 1646 PGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA----DAELLNTTE 1701 GQGAQ GMGREL A +P LD HL PLREVV+ A +A LL+ T Sbjct: 1552 TGQGAQRAGMGRELYARHPVFAEALDAAFGALDAHLDLPLREVVFAAEGSREAALLDETT 1611 Query: 1702 FAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLM 1761 + QPALFA+EVAL+RLLE G+ PGL+ GHSVGELSAAH +G RGRLM Sbjct: 1612 YTQPALFALEVALFRLLEHHGVTPGLLAGHSVGELSAAHAAGVLTLDDAAKLVAARGRLM 1671 Query: 1762 QALPGGGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQ 1818 QA GG M AV+A E+E+ P L +SVAAVNGP SVV+SG E V + L A Sbjct: 1672 QAARSGGAMIAVEAAEEEVLPYLEGRAAGLSVAAVNGPASVVISGDEEPALEVAELLRAS 1731 Query: 1819 GRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAE-DYGSADY 1877 GRR +RL VSHAFHS M+ +L+ FR VA V P +P++S VTG+L E + S Y Sbjct: 1732 GRRTKRLTVSHAFHSPHMDGVLDAFREVASTVAFSAPTVPIVSTVTGRLATEAELTSPQY 1791 Query: 1878 WVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPE 1937 W IR AVRF D+ + GAT FVE GP LT+L +L AVP +R RPE Sbjct: 1792 WANQIRAAVRFLDAARELAAQGATVFVEAGPDAVLTALTRAALEDTGATAVPLMRAGRPE 1851 Query: 1938 PFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 D A+ G GLPTYAF +WLA Sbjct: 1852 AETLTLGLGGAHAAGAALDAATFFPG-AATADGLPTYAFRRTHYWLA 1897 Score = 961 bits (2483), Expect = 0.0 Identities = 521/991 (52%), Positives = 652/991 (65%), Gaps = 21/991 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 R+ L + +++ AVL +V + AA+LG G +D +AF+D G S++ V+LRNRL Sbjct: 2646 RIAALPEDKRRDAVLGLVRDTVAAILGHAGGTSVDPERAFNDIGFDSMAGVDLRNRLGAA 2705 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPA-AAVRTRVRIDEPIAIVGMGCRYP 1128 TG+ L AT FD+PTP +A HLLS + +R A A A R R DEPIAIVGM CRYP Sbjct: 2706 TGLRLPATVVFDHPTPGAVAAHLLSRVSESSRPADAPTAARRRGPADEPIAIVGMACRYP 2765 Query: 1129 GGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFD 1188 GGVSSP +LW+LVA G D + EFP +RGWD+E L+DPDP+ G +Y R GGF+ D FD Sbjct: 2766 GGVSSPEELWRLVADGVDAVTEFPVNRGWDLENLYDPDPEQTGTSYVREGGFLHDADLFD 2825 Query: 1189 PGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS 1248 FFGISP EA A DPQQRLLLET+WE E+AG+DP LRGS+TGVF G D Y + Sbjct: 2826 REFFGISPREATATDPQQRLLLETAWETFENAGLDPALLRGSNTGVFTGAMYDDYASRLA 2885 Query: 1249 QA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 A + + G+++SV SGR+SY GL GPA++VDTACSSSLVALH+AA +LR+GECD Sbjct: 2886 SAPEEFEGFLLAGNLSSVVSGRLSYTYGLEGPAVTVDTACSSSLVALHMAAGALRSGECD 2945 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 LALAGG TV+ PS F+ FSRQRGL+ DGRCK+FA ADGTG+SEG G+L+++RLSDARR Sbjct: 2946 LALAGGVTVMNGPSTFVEFSRQRGLSPDGRCKSFAAGADGTGWSEGVGLLLVERLSDARR 3005 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 G VLA++ GSAVNQDGASNGLTAP+GP+Q+RVI AL++A +T AD+D VEAHGTGT Sbjct: 3006 NGHQVLAVVRGSAVNQDGASNGLTAPNGPSQERVIRQALANADLTPADIDAVEAHGTGTT 3065 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG+D PL+LGS+KSN+GHSQAAAGV G+IKM+EAMRH +LP T Sbjct: 3066 LGDPIEAQALLATYGQDRAEGRPLYLGSLKSNIGHSQAAAGVGGIIKMIEAMRHGVLPRT 3125 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDW GT+ LLTE WPA GRPRRAGVSSFG+SGTNAH Sbjct: 3126 LHVDAPSPHVDWETGTLALLTEETPWPA-AGRPRRAGVSSFGISGTNAHVIVEEAPAAPV 3184 Query: 1545 XXXXXXGP----GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLF 1600 GP GV+ W+VS + A + AQA RL ++V +L D+G+SL TTR++ Sbjct: 3185 DRRPAAGPESSGGVVPWIVSGKDEAALRAQARRLHQYVLDHPDLSPADIGHSLATTRAVL 3244 Query: 1601 EHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELC 1660 + A VVGA R+ LL GLA + G V + A P GKT F+F GQG+Q LGMGREL Sbjct: 3245 DQGAAVVGADRESLLRGLAAIERGESAGVVRARSARP-GKTAFLFTGQGSQRLGMGRELY 3303 Query: 1661 AGYPXXXXXXXXXXXELDRHLARPLREVVW----GADAELLNTTEFAQPALFAVEVALYR 1716 P LARP+++V++ A A L++ T F Q ALF VEVALYR Sbjct: 3304 ESSPVFAKALDEVCSRFRAELARPVKDVLFAQEDSATAALIDQTAFTQAALFCVEVALYR 3363 Query: 1717 LLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAG 1776 L E G P ++GHS+GE++AA++SG RGRLMQA GG M A+QA Sbjct: 3364 LFEHHGFTPDYLLGHSIGEVTAAYLSGVLDLDDACCLVAERGRLMQAAREGGAMAALQAS 3423 Query: 1777 EQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHS 1833 E+E+ + G+ V +A VNGP S+V+SG + V V A G R +RL VSHAFHS Sbjct: 3424 EEEVYASIAPYGDAVGIAGVNGPESLVISGDEDVVEEVTAAWRANGVRTKRLPVSHAFHS 3483 Query: 1834 VLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAE-DYGSADYWVRHIREAVRFADSV 1892 M+ +L++FR VA + P IPV+SNVTG L + S DYW HIREAVRF D V Sbjct: 3484 SHMDEVLDEFREVASGLSFRPPRIPVVSNVTGTLATDAQLTSPDYWATHIREAVRFLDGV 3543 Query: 1893 CFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXX 1952 + + G T F+E+GP LT+L SL + + V V LR+DRPE Sbjct: 3544 RYLEAQGVTDFLELGPDAVLTALTRGSLEEEAGVLVAALRRDRPEAETVAAAIAALRLRG 3603 Query: 1953 XXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 W +V G +RV LPTYAF HER+WL Sbjct: 3604 AAPAWDTVFP--GARRVALPTYAFQHERYWL 3632 Score = 691 bits (1782), Expect = 0.0 Identities = 409/959 (42%), Positives = 548/959 (57%), Gaps = 22/959 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGGDGSQRSA 89 V+ + D+G S+ + + L G+ +P V+D+P+ V +L S+ S Sbjct: 2679 VDPERAFNDIGFDSMAGVDLRNRLGAATGLRLPATVVFDHPTPGAVAAHLLSRV-SESSR 2737 Query: 90 DSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAA 149 +D A GP +EPIA++GMACR+ G V LW +A+ A+TE+P R Sbjct: 2738 PADAPTAARRRGPADEPIAIVGMACRYPGGVSSPEELWRLVADGVDAVTEFPVNRGWDLE 2797 Query: 150 ADWLGDEQET-----IYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHA 204 + D ++T G FL D + FD +FF I P EA DPQQRLLLET+W E+A Sbjct: 2798 NLYDPDPEQTGTSYVREGGFLHDADLFDREFFGISPREATATDPQQRLLLETAWETFENA 2857 Query: 205 GILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGP 264 G+ P L+ S+TGVF G DY L + + G SS+++ RLSY + GP Sbjct: 2858 GLDPALLRGSNTGVFTGAMYDDYASRLASAPEEFEGFLLAGNLSSVVSGRLSYTYGLEGP 2917 Query: 265 SLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCR 324 ++ +DTACSSSLVA H+A +L SGECDLA+ G V+ P + F +SP G C+ Sbjct: 2918 AVTVDTACSSSLVALHMAAGALRSGECDLALAGGVTVMNGPSTFVEFSRQRGLSPDGRCK 2977 Query: 325 AFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQI 384 +F A ADG EG G++++ERLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q Sbjct: 2978 SFAAGADGTGWSEGVGLLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQE 3037 Query: 385 SVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPN 444 V+ A AD+ PA+ID VEAHGTGT++GD IEA AL +G+ R +PL +GS+K N Sbjct: 3038 RVIRQALANADLTPADIDAVEAHGTGTTLGDPIEAQALLATYGQDRAEGRPLYLGSLKSN 3097 Query: 445 IGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGR 504 IGH + AAG+ G+IK + ++ G L + + P+P++ + LA++ E WPA GR Sbjct: 3098 IGHSQAAAGVGGIIKMIEAMRHGVLPRTLHVDAPSPHVDWETGTLALLTEETPWPA-AGR 3156 Query: 505 PRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP----GVLAWVVSARTAAGVGAQAG 560 PRRAGVSSFG GTNAH GP GV+ W+VS + A + AQA Sbjct: 3157 PRRAGVSSFGISGTNAHVIVEEAPAAPVDRRPAAGPESSGGVVPWIVSGKDEAALRAQAR 3216 Query: 561 RLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVAS 620 RL ++V +L D+G+SL TTR++ + A VVGA R+ LL GLA + G V + Sbjct: 3217 RLHQYVLDHPDLSPADIGHSLATTRAVLDQGAAVVGADRESLLRGLAAIERGESAGVVRA 3276 Query: 621 GVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVW-- 678 A P GKT F+F GQG+Q LGMGREL P LARP+++V++ Sbjct: 3277 RSARP-GKTAFLFTGQGSQRLGMGRELYESSPVFAKALDEVCSRFRAELARPVKDVLFAQ 3335 Query: 679 --GADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXX 736 A A L++ T F Q ALF VEVALYRL E G P ++GHS+GE++AA++SG Sbjct: 3336 EDSATAALIDQTAFTQAALFCVEVALYRLFEHHGFTPDYLLGHSIGEVTAAYLSGVLDLD 3395 Query: 737 XXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAR 793 RGRLMQA GG M A+QA E+E+ + G+ V +A VNGP S+V+SG Sbjct: 3396 DACCLVAERGRLMQAAREGGAMAALQASEEEVYASIAPYGDAVGIAGVNGPESLVISGDE 3455 Query: 794 EAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTG 853 + V V A G R +RL VSHAFHS M+ +L++FR VA + P IPV+SNVTG Sbjct: 3456 DVVEEVTAAWRANGVRTKRLPVSHAFHSSHMDEVLDEFREVASGLSFRPPRIPVVSNVTG 3515 Query: 854 QLVAE-DYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS 912 L + S DYW HIREAVRF D V + + G T F+E+GP LT+L SL + + Sbjct: 3516 TLATDAQLTSPDYWATHIREAVRFLDGVRYLEAQGVTDFLELGPDAVLTALTRGSLEEEA 3575 Query: 913 VVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 V V LR+DRPE W +V G +RV LPTYAF HER+WL Sbjct: 3576 GVLVAALRRDRPEAETVAAAIAALRLRGAAPAWDTVFP--GARRVALPTYAFQHERYWL 3632 Score = 670 bits (1728), Expect = 0.0 Identities = 448/1084 (41%), Positives = 574/1084 (52%), Gaps = 61/1084 (5%) Query: 1099 QNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWD 1158 +N S A A +V E IA+VG+ CR PG + PA W+L+ SG D + E PP R WD Sbjct: 5 ENNSVAAGAHTGQV---ERIAVVGLSCRLPGA-ADPAAFWELLHSGSDAVTEVPPGR-WD 59 Query: 1159 IERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALE 1218 + P + G R G F+ V FD GFFGISP EA AMDPQQRL+LE +WEALE Sbjct: 60 VPADAAPGSGSGG----RRGAFLDGVDRFDAGFFGISPREAAAMDPQQRLVLELTWEALE 115 Query: 1219 DAGIDPQALRGSSTGVFVGIYGDGYG-----LGTSQAQWYADTGHITSVASGRISYCLGL 1273 DA I P +LRGS T VFVG D Y G + G V +GR+SY LGL Sbjct: 116 DAAIVPASLRGSRTAVFVGTLRDDYTNLLYQYGDEAVTQHTMAGVNRGVIAGRVSYHLGL 175 Query: 1274 AGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDG 1333 GP+++VD+A SSSLVA+HLA SLR+GE A+ G + R L+ DG Sbjct: 176 RGPSLTVDSAQSSSLVAVHLACESLRSGESTTAVVAGVNLNLLAENATTEERFGALSPDG 235 Query: 1334 RCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGP 1393 F A+G EG G++VL+ LS A G + ++ G+AVN DGA++GLT PSG Sbjct: 236 VSYTFDARANGFVPGEGGGVVVLKPLSAALADGNRIHGVIRGTAVNNDGAADGLTVPSGT 295 Query: 1394 AQQRVISAALSDAGI-TGADVDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLG 1451 AQ+++I A + + G V VE HGTGT +GDP+EA AL A G + D PL +G Sbjct: 296 AQEQLIREAHRRSALGPGERVQYVELHGTGTPVGDPVEAAALGAALGAERGDADGPLRVG 355 Query: 1452 SIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWP 1511 S+K+N+GH + AAG+AG+IK + A+ H+ LPA+L+ + + + +++ E WP Sbjct: 356 SVKTNIGHLEGAAGMAGLIKTLLAITHRELPASLNFRTANPAIPLAELGLEVQRELSAWP 415 Query: 1512 AVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXG---PGVLAWVVSARTAAGVG 1568 RP AGVSSFG+ GTNAH G P L+WVV+A + + Sbjct: 416 RP-DRPLVAGVSSFGMGGTNAHVVVGEPPLPAAEPDTLTGSAAPSSLSWVVTANSEEALR 474 Query: 1569 AQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGV 1628 QA RL EF A D D GYSL T R++FEHRAVVVGA LL G+ + EGRPG Sbjct: 475 GQAARLAEFAGAENAPDPRDTGYSLATDRTVFEHRAVVVGADGAALLDGVRALAEGRPGA 534 Query: 1629 GVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREV 1688 GV G G T +F GQGAQ GMG+EL A +P LD L +PL EV Sbjct: 535 GVVRGRG-EAGATALLFTGQGAQRPGMGQELYAAHPVFADAFDAVAERLDPMLKQPLWEV 593 Query: 1689 VWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXX 1748 + A E L+ T QPALFA+EVAL+RLLESWG+RPG + GHS+GEL+AAHV+G Sbjct: 594 I--ASGEGLDETGRTQPALFAIEVALFRLLESWGVRPGFLAGHSIGELAAAHVAGVLSLD 651 Query: 1749 XXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPL---LGEQVSVAAVNGPGSVVLSGAR 1805 R RLMQALP GG M AV+A E+E+ P L ++S+AAVNGP SVV+SG Sbjct: 652 DAARLVAARARLMQALPAGGAMIAVEATEEEVLPHLEGLEARLSLAAVNGPASVVISGEA 711 Query: 1806 EAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTG 1865 +A V RLA GRR +RL VSHAFHS LM+ ML++F VA E+ P IPV+S +TG Sbjct: 712 DAAEDVAARLAEAGRRTKRLTVSHAFHSPLMDGMLKEFHKVAKELTYHAPRIPVVSTLTG 771 Query: 1866 QLVA-EDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS 1924 L + +D + YW +R AVRFAD+V GAT +EVGP L+SL + Sbjct: 772 ALASGDDLRTPCYWTDQVRHAVRFADAVRTLGELGATVLLEVGPDAVLSSLAD------- 824 Query: 1925 VVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 A PTLR RPE DW +V A GG+ V LPTYAF R W Sbjct: 825 --ATPTLRAGRPETRTLLTAVATAFVRGADVDWRAVHADAGGRSVPLPTYAFQRRRHWF- 881 Query: 1985 DRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTA 2044 + R + L AE +V H Sbjct: 882 ----DAAARKETRAIAPAADEVRSPAAASGVPSVPAGRAERLRYAED------LVTSHVT 931 Query: 2045 AVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHL 2104 AVL +LD F G TSL ELR L TG+ L + FD+PTP +L L Sbjct: 932 AVLEYGDGERLDPRVPFQKLGFTSLMTTELRAALAEATGLALPGSLLFDHPTPRELTAFL 991 Query: 2105 LSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKRE 2164 + L T PE + F++ DAG + IV +A +T+P + Sbjct: 992 ATRL---ADTTDEPEAG------EEFIRPADAG---EPIAIVGMACRFPGGITSPA--QL 1037 Query: 2165 WKEV 2168 WK V Sbjct: 1038 WKLV 1041 Score = 666 bits (1718), Expect = 0.0 Identities = 408/974 (41%), Positives = 540/974 (55%), Gaps = 21/974 (2%) Query: 16 THYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV 75 +H A D ++ +P + LG S+ + L++ G+ +P ++D+P+ + Sbjct: 928 SHVTAVLEYGDGERLDPRVPFQKLGFTSLMTTELRAALAEATGLALPGSLLFDHPTPRE- 986 Query: 76 IKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKS 135 + + L + + + + G + EPIA++GMACRF G + LW ++E Sbjct: 987 LTAFLATRLADTTDEPEAGEEFIRPADAGEPIAIVGMACRFPGGITSPAQLWKLVSEGGD 1046 Query: 136 AITEYPARR-----LGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQ 190 AITE+P R L A D G +G FL D FD FF I P EA MDPQQ Sbjct: 1047 AITEFPVNRGWPDDLYDADPDRPG-RSAVRHGGFLHDAGEFDADFFGISPREALAMDPQQ 1105 Query: 191 RLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSI 250 RLLLE++W A+E AGI P TL+ S TGVFVG ++ +Y + TG ++S+ Sbjct: 1106 RLLLESAWEAVERAGIDPDTLRGSRTGVFVGATALEYGPRMHEAPESVQGSVLTGSTTSV 1165 Query: 251 IANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRG 310 ++ R++Y L + GP++ DTACSSSLVA HLA +SL SGE LA+ G V+ SP ++ Sbjct: 1166 MSGRIAYQLGLLGPAVTTDTACSSSLVALHLAIRSLRSGETSLALAGGATVMSSPGMFVE 1225 Query: 311 FQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDG 370 F ++P G C++F A ADG EG G++++ERLSDARR G VLAV+ GSAVNQDG Sbjct: 1226 FSRQRGLAPDGRCKSFAAGADGTGWSEGVGLLLVERLSDARRNGHQVLAVVRGSAVNQDG 1285 Query: 371 RSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR 430 SNG+ APN +Q V+ A + + E+D VEAHGTGT +GD IEA AL +G GR Sbjct: 1286 ASNGLTAPNGLSQQRVVRQALADSGLAATEVDAVEAHGTGTRLGDPIEAEALMATYGTGR 1345 Query: 431 QAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLA 490 P+ +GS+K NIGH + AAG+ G+IK V ++ G L + + P+P + + L Sbjct: 1346 DGLPPVYLGSLKSNIGHAQAAAGVGGVIKMVEAIRHGVLPRTLHVDEPSPRVDWNAGALE 1405 Query: 491 VVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH---XXXXXXXXXXXXXXXXXGPGVLA-WV 546 ++ + WP GRPRRA VSSFG GTNAH P V A W+ Sbjct: 1406 LLTGERAWPD-TGRPRRAAVSSFGISGTNAHVVLEQAPDAPPPSAAPPATQAPAVPAPWL 1464 Query: 547 VSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGL 606 +SAR + AQA RL + R + +G +L TTR+ FE RAVV+ R LAGL Sbjct: 1465 LSARDPDTLRAQAERLRAYADGDRAPEPAAIGRALATTRTAFEQRAVVLAEDRAGYLAGL 1524 Query: 607 AEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELD 666 ++ G GV +G A G+T F+F GQGAQ GMGREL A +P LD Sbjct: 1525 DALIRGADAPGVVTGSARSAGRTAFLFTGQGAQRAGMGRELYARHPVFAEALDAAFGALD 1584 Query: 667 RHLARPLREVVWGA----DAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVG 722 HL PLREVV+ A +A LL+ T + QPALFA+EVAL+RLLE G+ PGL+ GHSVG Sbjct: 1585 AHLDLPLREVVFAAEGSREAALLDETTYTQPALFALEVALFRLLEHHGVTPGLLAGHSVG 1644 Query: 723 ELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL---GEQVSVA 779 ELSAAH +G RGRLMQA GG M AV+A E+E+ P L +SVA Sbjct: 1645 ELSAAHAAGVLTLDDAAKLVAARGRLMQAARSGGAMIAVEAAEEEVLPYLEGRAAGLSVA 1704 Query: 780 AVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVY 839 AVNGP SVV+SG E V + L A GRR +RL VSHAFHS M+ +L+ FR VA V Sbjct: 1705 AVNGPASVVISGDEEPALEVAELLRASGRRTKRLTVSHAFHSPHMDGVLDAFREVASTVA 1764 Query: 840 AGRPAIPVISNVTGQLVAE-DYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAG 898 P +P++S VTG+L E + S YW IR AVRF D+ + GAT FVE GP Sbjct: 1765 FSAPTVPIVSTVTGRLATEAELTSPQYWANQIRAAVRFLDAARELAAQGATVFVEAGPDA 1824 Query: 899 GLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVG 958 LT+L +L AVP +R RPE D A+ G G Sbjct: 1825 VLTALTRAALEDTGATAVPLMRAGRPEAETLTLGLGGAHAAGAALDAATFFPG-AATADG 1883 Query: 959 LPTYAFAHERFWLA 972 LPTYAF +WLA Sbjct: 1884 LPTYAFRRTHYWLA 1897 Score = 79.3 bits (194), Expect = 6e-12 Identities = 45/106 (42%), Positives = 60/106 (56%), Gaps = 1/106 (0%) Query: 2022 RLQGLSDAEQQAAVLA-MVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKT 2080 RL L D EQ+ L +V AAVLG +D G+AF + G SL+AVELRN+L T Sbjct: 4391 RLGALPDEEQRVEALTDLVRVQVAAVLGHSDPGSVDPGRAFQELGFDSLTAVELRNQLST 4450 Query: 2081 LTGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDAL 2126 ++G+ L T FD+P+P LA HL + + ATP L +D L Sbjct: 4451 VSGLRLPTTLVFDHPSPAALAAHLRQRITVEEGAAATPVLADLDRL 4496 Score = 77.8 bits (190), Expect = 2e-11 Identities = 40/101 (39%), Positives = 59/101 (58%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 R+ L + +++ AVL +V + AA+LG G +D +AF+D G S++ V+LRNRL Sbjct: 2646 RIAALPEDKRRDAVLGLVRDTVAAILGHAGGTSVDPERAFNDIGFDSMAGVDLRNRLGAA 2705 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDR 2122 TG+ L AT FD+PTP +A HLLS + + P R Sbjct: 2706 TGLRLPATVVFDHPTPGAVAAHLLSRVSESSRPADAPTAAR 2746 Score = 72.4 bits (176), Expect = 8e-10 Identities = 42/110 (38%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Query: 1010 RLQGLSDAEQQAAVLA-MVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKT 1068 RL L D EQ+ L +V AAVLG +D G+AF + G SL+AVELRN+L T Sbjct: 4391 RLGALPDEEQRVEALTDLVRVQVAAVLGHSDPGSVDPGRAFQELGFDSLTAVELRNQLST 4450 Query: 1069 LTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPI 1118 ++G+ L T FD+P+P LA HL + + +A + R+ I Sbjct: 4451 VSGLRLPTTLVFDHPSPAALAAHLRQRITVEEGAAATPVLADLDRLKSAI 4500 >tr|Q93HJ5|Q93HJ5_STRAW Tax_Id=33903 (olmA1)SubName: Full=Modular polyketide synthase;[Streptomyces avermitilis] Length = 6146 Score = 1520 bits (3936), Expect = 0.0 Identities = 903/1900 (47%), Positives = 1115/1900 (58%), Gaps = 65/1900 (3%) Query: 112 MACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGF 171 MACR G GP +FLA ++ +GAA D + G FL+ V+ F Sbjct: 1 MACRLPG---AAGPA-EFLALLRNG-----EDAVGAAPGDRRYAPRR---GGFLDSVDEF 48 Query: 172 DNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLL 231 D FF I P EAA MDPQQRL+LE SW ALE AGI P L S GVFVG + DY L Sbjct: 49 DAGFFGISPREAAAMDPQQRLVLELSWEALEDAGIPPARLGGSGAGVFVGAIADDYATLS 108 Query: 232 FPGGRKP-TIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGE 290 G T TG + IIANR+SY L + GPS +D+ SSSLVA HLA +SL GE Sbjct: 109 RAAGADAATPQTTTGLNRGIIANRVSYTLGLRGPSFTVDSGQSSSLVAVHLAAESLRRGE 168 Query: 291 CDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDA 350 C +A+ G N++++ + + G +SP G C FDARA+G VRGEG GVVVL+ L+DA Sbjct: 169 CSVALAGGVNLILAEDSTVAVERFGALSPDGYCYTFDARANGYVRGEGGGVVVLKPLADA 228 Query: 351 RRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTG 410 G + +L GSAVN DG G+ P+ Q +VL +A + A I PA + YVE HGTG Sbjct: 229 IADGDDIHCILAGSAVNNDGGGEGLTVPDRAGQEAVLTAAYEQAGISPAAVGYVELHGTG 288 Query: 411 TSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLL 470 T GD +EA A+G V G GR A +PL++GS+K NIGHLEGAAGIAGL+K VL ++ ++ Sbjct: 289 TPTGDPVEAAAVGAVLGAGRPAGQPLLVGSVKTNIGHLEGAAGIAGLLKAVLAVRHREIP 348 Query: 471 PSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXX 530 + PNP IP AELG+ V WP G P GVSSFG GGTN H Sbjct: 349 ATLHHASPNPAIPMAELGIGVNTALTPWPEQAG-PLVVGVSSFGMGGTNCHVVLTEPAGY 407 Query: 531 XXXXXXXXG-------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVT 583 P L +VS R + AQA +L + + L DV ++L Sbjct: 408 DAAARPATAGIRPAGTPAPL--LVSGRDEQALRAQARKLRDHLDTHPGLPLRDVAHTLAA 465 Query: 584 TRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGM 643 R+ RAV++ A R+++ AGLA + +G PG + G PG FVF GQG+Q GM Sbjct: 466 ARAPLARRAVLLAADREDVSAGLARLADGTPGADLVRGTVSPGA-LAFVFTGQGSQRPGM 524 Query: 644 GRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGAD----AELLNTTEFAQPALFAVE 699 EL LD L RPLR+V++ A+ A LL+ TEF QPALFAVE Sbjct: 525 TAELYRTSAEYAAALDEVCASLDPWLRRPLRDVLFAAEGSDEAALLDRTEFTQPALFAVE 584 Query: 700 VALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMY 759 VAL+R E G+ P ++GHSVGEL+AAHV+G RGRLMQ P G M Sbjct: 585 VALFRYAEHCGLTPRFLLGHSVGELAAAHVAGVLSLADACTLVAARGRLMQDRPATGAMV 644 Query: 760 AVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAF 819 +VQA E EL P + E V++AA+NGP S V++G +AV V AA+GR+ +RL VSHAF Sbjct: 645 SVQATEDELAPFVSESVTLAALNGPASTVIAGDEDAVLAVAAHWAARGRKTKRLRVSHAF 704 Query: 820 HSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAE-DYGSADYWVRHIREAVRFAD 878 HS M+ ML +FR +A + G P IP++SN TG L+ E D S +YWVRH R AVRF D Sbjct: 705 HSPHMDGMLTEFRRIAAGLTFGAPRIPIVSNETGTLLTEADARSPEYWVRHARAAVRFLD 764 Query: 879 SVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLR-KDRPEPFXXXXXXXXXX 937 V G T +E+GP G L+++ + L V VP LR +DR EP Sbjct: 765 GVRLLEDQGVTTLLELGPDGVLSAMARDCLRDAGTVCVPLLRGRDRTEPEALLAALAGLY 824 Query: 938 XXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADR--------FXXXXXXXXXXXLXX 989 DW G +RV LPTYAF R WL + Sbjct: 825 VRGVPMDWERTATEAGARRVPLPTYAFQRRRHWLPEPSASASRPVVNGGGHAGQAGHAGQ 884 Query: 990 XXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAF 1049 R + + + L +V + TA VLG + +AF Sbjct: 885 AGRAGQAGHAGHDGEPAPAVRDRTTPELVRDRTTLELVRDATAQVLGHASPDDVATHEAF 944 Query: 1050 SDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVR 1109 + G +SL EL RL TG + T FD+PTP LA L + + + P + Sbjct: 945 RELGFSSLMLAELGERLTEATGRRVPTTLLFDHPTPDALARRLEADGAERTDAGPVSPPA 1004 Query: 1110 TRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDA 1169 D+PI IVGMGCR PGGV SP LW+ VA+GGD I P DRGW+ F + Sbjct: 1005 AAAHDDDPIVIVGMGCRLPGGVRSPEDLWRFVAAGGDAISALPVDRGWEFAADFPGE--- 1061 Query: 1170 LGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRG 1229 GGF++DVA+FD GFFGISP EALAMDPQQRLLLETSWEALE AG+D LRG Sbjct: 1062 --------GGFLADVAEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGVDALKLRG 1113 Query: 1230 SSTGVFVGIYGDGYGLG---TSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSS 1286 S TGVFVG YG TS A + TG SV SGRI+Y LGL GPA++VDTACSS Sbjct: 1114 SRTGVFVGASPSEYGPRLHETSDADGHVLTGTAPSVLSGRIAYVLGLEGPALTVDTACSS 1173 Query: 1287 SLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTG 1346 SLVALHLAA +LR GECDLALAGG TV+AT +F F+RQ GLA DGRCKAFAD ADGTG Sbjct: 1174 SLVALHLAAQALRGGECDLALAGGVTVMATSGMFAEFARQGGLAPDGRCKAFADGADGTG 1233 Query: 1347 FSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDA 1406 + EG GML +QRLSDA R G+PVLA++ GSAVN DGASNGLTAP+GP+QQRVI AL+ A Sbjct: 1234 WGEGVGMLAVQRLSDAVRDGRPVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIRQALASA 1293 Query: 1407 GITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGV 1466 G++ ADVD+VEAHGTGT LGDPIEAQALLATYG+D D PLWLGS+KSN+GH+QAAAGV Sbjct: 1294 GLSAADVDMVEAHGTGTSLGDPIEAQALLATYGQDRPDDRPLWLGSVKSNIGHTQAAAGV 1353 Query: 1467 AGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFG 1526 AGVIK V A+R+ LLP TLH+D+P+ VDWS G V+LLTE REWP G PRRAGVS+FG Sbjct: 1354 AGVIKSVLALRNGLLPKTLHVDEPTPEVDWSAGAVELLTEGREWPETDG-PRRAGVSAFG 1412 Query: 1527 VSGTNAHXXXXXXXXXXXXXXXXXGPGVLA-WVVSARTAAGVGAQAGRLLEFVRAGRELD 1585 +SGTNAH G+L WVVSAR+ + AQA RL + VR L Sbjct: 1413 ISGTNAHVILEQAPSVEEPVTAPADDGLLVPWVVSARSEEALRAQARRLADHVRES-GLR 1471 Query: 1586 AGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVF 1645 DVG SL TR+ EHRAV+V LA L + EGR +GV + GG T F+F Sbjct: 1472 PADVGLSLAVTRAGLEHRAVLVAEDEAGFLAHLDALAEGR----TPAGVVVEGG-TAFLF 1526 Query: 1646 PGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQP 1705 GQG+Q GMGREL + +P D L LREVV+G L+ TE+AQP Sbjct: 1527 SGQGSQRAGMGRELYSAHPVFAAAFDEVCAAFDGLLPGALREVVFGGAG--LDRTEWAQP 1584 Query: 1706 ALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALP 1765 ALFA+EVAL+ L+ SWG+R +++GHS+GEL+AA+V+G RGRLMQALP Sbjct: 1585 ALFALEVALFELVSSWGVRADVLLGHSIGELAAAYVAGVWSLADACRIVAARGRLMQALP 1644 Query: 1766 GGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRL 1825 GG M AV+A E EL L G VSVAAVNGP S+VLSG E V+ + A QGRR ++L Sbjct: 1645 EGGAMVAVEAAEDELPDLPG-GVSVAAVNGPRSLVLSGDEEPVTALAQAFAEQGRRTKQL 1703 Query: 1826 AVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREA 1885 VSHAFHS MEPML +F V P IPV+SNVTG++ +++ + YWVRH+REA Sbjct: 1704 TVSHAFHSARMEPMLAEFAETLAAVEFRPPRIPVVSNVTGEMAGDEFTTPAYWVRHVREA 1763 Query: 1886 VRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRPEPFXXXX 1943 VRFAD V AH+AG R++E+GP G LT+L ++ A V AVP LR D+PE Sbjct: 1764 VRFADGVGAAHAAGVRRYLELGPDGTLTTLAHDTAHDAGRDVAAVPALRGDQPETRTVVT 1823 Query: 1944 XXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DW + A G + LPTYAF H R+WL Sbjct: 1824 AVGRLYATGLTVDWPAFFAPYGARPTELPTYAFQHRRYWL 1863 Score = 952 bits (2460), Expect = 0.0 Identities = 529/981 (53%), Positives = 640/981 (65%), Gaps = 24/981 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL G +D E++ +L +V A LG GA + + F D G SL+AV+LRNRL Sbjct: 3882 RLAGSTDGERERELLDLVRTAAALALGHRGAEAITPSKPFKDLGFDSLTAVDLRNRLTAA 3941 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNR--SAPAAAVRTRVRIDEPIAIVGMGCRY 1127 TGV L AT FD+PTP A L + L + ++ + T D+P+ IV M CR+ Sbjct: 3942 TGVRLPATLVFDHPTPLAAAVELRTRLFGGDALPTSAGSVAPTAAEADDPVVIVAMACRF 4001 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PG +SP +LW L+A+G D IG+FP DRGW + A +++ GGF+ DVA+F Sbjct: 4002 PGEATSPEKLWDLIAAGKDGIGDFPADRGWSV---------AADAAFSQTGGFLPDVAEF 4052 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGL-- 1245 D GFFGISP EALAMDPQQRLLLETSWEALE AG+D LRGS TGVFVG YG Sbjct: 4053 DAGFFGISPREALAMDPQQRLLLETSWEALERAGVDALKLRGSRTGVFVGAGSHDYGTLL 4112 Query: 1246 -GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 Q YA TG + SV SGRI+Y LGL GPA++VDTACSSSLVALHLAA +LR GECD Sbjct: 4113 TSLEGGQDYALTGAVGSVLSGRIAYVLGLEGPALTVDTACSSSLVALHLAAQALRGGECD 4172 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 +ALAGG V+ATP F F+RQ GLA DGRCKAFAD ADGTG+ EG G+LVL RLS+ARR Sbjct: 4173 VALAGGVAVMATPDAFDAFARQGGLAPDGRCKAFADGADGTGWGEGVGVLVLTRLSEARR 4232 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 G VLA++ GSAVN DGASNGLTAP+GP+QQRVI AL+ AG++ ADVD+VEAHGTGT Sbjct: 4233 RGHDVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIRQALASAGLSAADVDMVEAHGTGTS 4292 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG+D D PLWLGS+KSN+GH+QAAAGVAGVIK V A+R+ LLPAT Sbjct: 4293 LGDPIEAQALLATYGQDRPADRPLWLGSVKSNIGHTQAAAGVAGVIKSVLALRNGLLPAT 4352 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D+PS VDWS G V+LLTE REWP G PRRAGVS+FG+SGTNAH Sbjct: 4353 LHVDEPSREVDWSAGAVELLTEGREWPETDG-PRRAGVSAFGISGTNAHVILEQAPSVEE 4411 Query: 1545 XXXXXXGPGVLA-WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHR 1603 G+L WVVSAR+ + AQA RL + V A +L DVGYSL TR+ EHR Sbjct: 4412 PVTAPADDGLLVPWVVSARSEEALRAQARRLADHV-AATDLTVADVGYSLAGTRAGLEHR 4470 Query: 1604 AVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGY 1663 AV+ G R++ L LA + EG G+ GVA GG T F+F GQGAQ LGMGREL + Sbjct: 4471 AVLTGREREDFLVQLAALAEGASAAGMVRGVAGEGG-TAFLFTGQGAQRLGMGRELYERF 4529 Query: 1664 PXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGM 1723 P +LD L RP++EVV+ DA L+ T F Q LFA+EVAL+ L+ SWG+ Sbjct: 4530 PVFAAAFDGVCAQLDLLLERPVKEVVF-TDAPALDRTVFTQAGLFALEVALFELVSSWGV 4588 Query: 1724 RPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPL 1783 R +++GHS+GEL+AA+V+G RGRLMQALP GG M AV+A E EL P Sbjct: 4589 RADVLLGHSIGELAAAYVAGVWSLADACRIVAARGRLMQALPEGGAMVAVEAAEDEL-PD 4647 Query: 1784 LGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQF 1843 L E VSVAAVNGP S+VLSG E V+ + A QGRR ++LAVSHAFHS MEPML +F Sbjct: 4648 LPEGVSVAAVNGPRSLVLSGDEEPVTALARTFAEQGRRTKQLAVSHAFHSARMEPMLAEF 4707 Query: 1844 RAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRF 1903 V P IPV+SNVTG + ++ + YWVRH+REAVRFAD V + G RF Sbjct: 4708 AETLAAVEFRSPRIPVVSNVTGGMAGAEFTTPAYWVRHVREAVRFADGVATVLARGVDRF 4767 Query: 1904 VEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVL 1961 +E+GP G LT++ EE+L V VP L +RPE DW + Sbjct: 4768 LELGPRGALTAMAEETLDHTGADAVCVPVLHPERPEDATLLHALATASVTGAAVDWTTPF 4827 Query: 1962 AGCGGQRVGLPTYAFAHERFW 1982 A C + LPTYAF RFW Sbjct: 4828 A-C-ARTTELPTYAFQRRRFW 4846 Score = 803 bits (2074), Expect = 0.0 Identities = 473/994 (47%), Positives = 593/994 (59%), Gaps = 31/994 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL+ + A+ +V AAVLG ++ F G SL VE RNRL Sbjct: 2360 RLGGLTGDALRQALADLVSTEVAAVLGLPPTDRVREDTTFRALGFDSLIGVEFRNRLAAA 2419 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHH-------QNRSAPAAAVRTRVRIDEPIAIVG 1122 TG L + FD+PTP +L +HL + L + R APA RT D+P+ IV Sbjct: 2420 TGRRLPPSLIFDHPTPGRLVEHLAAGLDGTGPNTAGEERVAPA---RTH---DDPVVIVS 2473 Query: 1123 MGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVS 1182 CR+PGGV++P +LWQLV GGD IG FP DRGWD++RL+DPDP G +Y R GGF++ Sbjct: 2474 AACRFPGGVTTPEELWQLVLDGGDAIGPFPADRGWDLDRLYDPDPGNPGTSYVREGGFLT 2533 Query: 1183 DVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDG 1242 DVADFD FFGISP EALAMDPQQRLLLETSWEALE AGI P +L GS TGVFVG G Sbjct: 2534 DVADFDAAFFGISPREALAMDPQQRLLLETSWEALERAGIVPASLAGSRTGVFVGSNGQD 2593 Query: 1243 YG--LGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRA 1300 Y LG S+ + + TG +SV SGRI+Y LGL GPA++VDTACSSSLVALHLA +L A Sbjct: 2594 YATLLGESEVEGHVLTGTASSVLSGRIAYTLGLEGPALTVDTACSSSLVALHLAVQALNA 2653 Query: 1301 GECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLS 1360 GECDLALA G TV+++P IF+ FSRQRGL+ DGRCKAF ADGTG+ EG G ++L+RLS Sbjct: 2654 GECDLALAAGVTVMSSPEIFVEFSRQRGLSADGRCKAFGPDADGTGWGEGVGTVLLERLS 2713 Query: 1361 DARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHG 1420 DARR G VL ++ G+AVNQDGASNGL+AP+GPAQQRVI AL+DAG +DVD VEAHG Sbjct: 2714 DARRLGHDVLGVVRGTAVNQDGASNGLSAPNGPAQQRVIRQALADAGCVPSDVDAVEAHG 2773 Query: 1421 TGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQL 1480 TGTRLGDPIEAQALLATYGRD D PLWLGS+KSN+GH+QAAAG+AGV+K + AMRH Sbjct: 2774 TGTRLGDPIEAQALLATYGRDRPADRPLWLGSVKSNIGHTQAAAGMAGVLKTLSAMRHGQ 2833 Query: 1481 LPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXX 1540 LP TLH +P+ VDW+ G V+LLTE R WPA RPRRAGVS+FGVSGTNAH Sbjct: 2834 LPRTLHAARPTPKVDWTEGAVELLTETRPWPATGARPRRAGVSAFGVSGTNAHVILEQAP 2893 Query: 1541 XXXXXXXXXXGPGV----LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTT 1596 P + + WV++A++ + AQA RL + E +VG SLVTT Sbjct: 2894 APQPARPAVLPPLLNSPSVPWVLTAKSEEALAAQADRLSARL---PEAAPAEVGRSLVTT 2950 Query: 1597 RSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMG 1656 R+ + RAV++G G AGL + G V G A G+ VFVFPGQGAQW GM Sbjct: 2951 RATWPERAVLIGDGSPHFAAGLGALAGGAGDPRVVRGTADTRGRVVFVFPGQGAQWAGMA 3010 Query: 1657 RELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAVEVALY 1715 L P L R L EV+ DA L+ + QPA +AV V+L Sbjct: 3011 ARLWESSPVFAQWMDRCAEVLARLTDWSLTEVIHETQDAPGLDRVDVVQPASWAVSVSLA 3070 Query: 1716 RLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLM-QALPGGGVMYAVQ 1774 L + G+ P V+GHS GE++AA V+G +R RL+ + L G G M +V Sbjct: 3071 GLWRACGVEPAAVVGHSQGEIAAACVAGGLSLEDGAALVTLRSRLIAEELSGHGGMVSVA 3130 Query: 1775 AGEQELRPLLGE---QVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAF 1831 + + + VAA N S V+SG EA++ ++ A+G R RR+ V +A Sbjct: 3131 LSPADTAERIARWNGGICVAANNSRRSTVVSGEPEALAELLAECEAEGVRARRIPVDYAS 3190 Query: 1832 HSVLMEPMLEQFRAVADEVYAGRPA-IPVISNVTGQLVAEDYGSADYWVRHIREAVRFAD 1890 HS +E + Q +A V A RP IP S TG + ADYW R++R V F Sbjct: 3191 HSAQVERIERQLTELAAGV-APRPGDIPFHSTTTGGPLDTTGLDADYWYRNLRRPVLFGP 3249 Query: 1891 SVCFAHSAGATRFVEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRPEPFXXXXXXXXX 1948 + G F+E+ P L +++++ + AV +LR+D P Sbjct: 3250 VTEELLAQGHDVFLEMSPHPVLVPAVQDAVDATGTTAAAVGSLRRDDGGPERFTLSLAEA 3309 Query: 1949 XXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 DW +VL G +RV LPTY F RFW Sbjct: 3310 FVRGAPVDWTAVLGTSGARRVELPTYPFQRGRFW 3343 Score = 726 bits (1875), Expect = 0.0 Identities = 429/945 (45%), Positives = 558/945 (59%), Gaps = 27/945 (2%) Query: 35 PLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPS----AHDVIKSVLGGDGSQRSAD 90 P +DLG S+ + + L+ G+ +P V+D+P+ A ++ + GGD SA Sbjct: 3920 PFKDLGFDSLTAVDLRNRLTAATGVRLPATLVFDHPTPLAAAVELRTRLFGGDALPTSAG 3979 Query: 91 SDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA 150 S A ++P+ ++ MACRF G+ LWD +A K I ++PA R + AA Sbjct: 3980 SVAPTAA----EADDPVVIVAMACRFPGEATSPEKLWDLIAAGKDGIGDFPADRGWSVAA 4035 Query: 151 DWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKT 210 D + G FL DV FD FF I P EA MDPQQRLLLETSW ALE AG+ Sbjct: 4036 DAAFSQT----GGFLPDVAEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGVDALK 4091 Query: 211 LKLSHTGVFVGVSSTDYVRLL--FPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVI 268 L+ S TGVFVG S DY LL GG+ + TG S+++ R++Y L + GP+L + Sbjct: 4092 LRGSRTGVFVGAGSHDYGTLLTSLEGGQDYAL---TGAVGSVLSGRIAYVLGLEGPALTV 4148 Query: 269 DTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDA 328 DTACSSSLVA HLA ++L GECD+A+ G V+ +P+ + F G ++P G C+AF Sbjct: 4149 DTACSSSLVALHLAAQALRGGECDVALAGGVAVMATPDAFDAFARQGGLAPDGRCKAFAD 4208 Query: 329 RADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLD 388 ADG GEG GV+VL RLS+ARR G VLAV+ GSAVN DG SNG+ APN +Q V+ Sbjct: 4209 GADGTGWGEGVGVLVLTRLSEARRRGHDVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIR 4268 Query: 389 SACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHL 448 A A + A++D VEAHGTGTS+GD IEA AL +G+ R A +PL +GS+K NIGH Sbjct: 4269 QALASAGLSAADVDMVEAHGTGTSLGDPIEAQALLATYGQDRPADRPLWLGSVKSNIGHT 4328 Query: 449 EGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRA 508 + AAG+AG+IK+VL L+ G L + + P+ + ++ + ++ E +EWP G PRRA Sbjct: 4329 QAAAGVAGVIKSVLALRNGLLPATLHVDEPSREVDWSAGAVELLTEGREWPETDG-PRRA 4387 Query: 509 GVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLA-WVVSARTAAGVGAQAGRLLEFVR 567 GVS+FG GTNAH G+L WVVSAR+ + AQA RL + V Sbjct: 4388 GVSAFGISGTNAHVILEQAPSVEEPVTAPADDGLLVPWVVSARSEEALRAQARRLADHV- 4446 Query: 568 AGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGG 627 A +L DVGYSL TR+ EHRAV+ G R++ L LA + EG G+ GVA GG Sbjct: 4447 AATDLTVADVGYSLAGTRAGLEHRAVLTGREREDFLVQLAALAEGASAAGMVRGVAGEGG 4506 Query: 628 KTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNT 687 T F+F GQGAQ LGMGREL +P +LD L RP++EVV+ DA L+ Sbjct: 4507 -TAFLFTGQGAQRLGMGRELYERFPVFAAAFDGVCAQLDLLLERPVKEVVF-TDAPALDR 4564 Query: 688 TEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGR 747 T F Q LFA+EVAL+ L+ SWG+R +++GHS+GEL+AA+V+G RGR Sbjct: 4565 TVFTQAGLFALEVALFELVSSWGVRADVLLGHSIGELAAAYVAGVWSLADACRIVAARGR 4624 Query: 748 LMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQG 807 LMQALP GG M AV+A E EL P L E VSVAAVNGP S+VLSG E V+ + A QG Sbjct: 4625 LMQALPEGGAMVAVEAAEDEL-PDLPEGVSVAAVNGPRSLVLSGDEEPVTALARTFAEQG 4683 Query: 808 RRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWV 867 RR ++LAVSHAFHS MEPML +F V P IPV+SNVTG + ++ + YWV Sbjct: 4684 RRTKQLAVSHAFHSARMEPMLAEFAETLAAVEFRSPRIPVVSNVTGGMAGAEFTTPAYWV 4743 Query: 868 RHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRPE 925 RH+REAVRFAD V + G RF+E+GP G LT++ EE+L V VP L +RPE Sbjct: 4744 RHVREAVRFADGVATVLARGVDRFLELGPRGALTAMAEETLDHTGADAVCVPVLHPERPE 4803 Query: 926 PFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 DW + A C + LPTYAF RFW Sbjct: 4804 DATLLHALATASVTGAAVDWTTPFA-C-ARTTELPTYAFQRRRFW 4846 Score = 700 bits (1807), Expect = 0.0 Identities = 421/943 (44%), Positives = 552/943 (58%), Gaps = 32/943 (3%) Query: 37 RDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGGDGSQRSADSDTGCA 96 R+LG S+ + + L++ G VP ++D+P+ D + L DG++R+ D+ Sbjct: 945 RELGFSSLMLAELGERLTEATGRRVPTTLLFDHPTP-DALARRLEADGAERT-DAGPVSP 1002 Query: 97 VLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDE 156 ++PI ++GM CR G V LW F+A AI+ P R AAD+ G+ Sbjct: 1003 PAAAAHDDDPIVIVGMGCRLPGGVRSPEDLWRFVAAGGDAISALPVDRGWEFAADFPGE- 1061 Query: 157 QETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHT 216 G FL DV FD FF I P EA MDPQQRLLLETSW ALE AG+ L+ S T Sbjct: 1062 -----GGFLADVAEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGVDALKLRGSRT 1116 Query: 217 GVFVGVSSTDYVRLLFPGGRKPTIWDN-----TGGSSSIIANRLSYFLDVNGPSLVIDTA 271 GVFVG S ++Y G R D TG + S+++ R++Y L + GP+L +DTA Sbjct: 1117 GVFVGASPSEY------GPRLHETSDADGHVLTGTAPSVLSGRIAYVLGLEGPALTVDTA 1170 Query: 272 CSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARAD 331 CSSSLVA HLA ++L GECDLA+ G V+ + ++ F G ++P G C+AF AD Sbjct: 1171 CSSSLVALHLAAQALRGGECDLALAGGVTVMATSGMFAEFARQGGLAPDGRCKAFADGAD 1230 Query: 332 GMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSAC 391 G GEG G++ ++RLSDA R GR VLAV+ GSAVN DG SNG+ APN +Q V+ A Sbjct: 1231 GTGWGEGVGMLAVQRLSDAVRDGRPVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIRQAL 1290 Query: 392 KCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGA 451 A + A++D VEAHGTGTS+GD IEA AL +G+ R +PL +GS+K NIGH + A Sbjct: 1291 ASAGLSAADVDMVEAHGTGTSLGDPIEAQALLATYGQDRPDDRPLWLGSVKSNIGHTQAA 1350 Query: 452 AGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVS 511 AG+AG+IK+VL L+ G L + + P P + ++ + ++ E +EWP G PRRAGVS Sbjct: 1351 AGVAGVIKSVLALRNGLLPKTLHVDEPTPEVDWSAGAVELLTEGREWPETDG-PRRAGVS 1409 Query: 512 SFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLA-WVVSARTAAGVGAQAGRLLEFVRAGR 570 +FG GTNAH G+L WVVSAR+ + AQA RL + VR Sbjct: 1410 AFGISGTNAHVILEQAPSVEEPVTAPADDGLLVPWVVSARSEEALRAQARRLADHVRES- 1468 Query: 571 ELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTV 630 L DVG SL TR+ EHRAV+V LA L + EGR +GV + GG T Sbjct: 1469 GLRPADVGLSLAVTRAGLEHRAVLVAEDEAGFLAHLDALAEGR----TPAGVVVEGG-TA 1523 Query: 631 FVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEF 690 F+F GQG+Q GMGREL + +P D L LREVV+G L+ TE+ Sbjct: 1524 FLFSGQGSQRAGMGRELYSAHPVFAAAFDEVCAAFDGLLPGALREVVFGGAG--LDRTEW 1581 Query: 691 AQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQ 750 AQPALFA+EVAL+ L+ SWG+R +++GHS+GEL+AA+V+G RGRLMQ Sbjct: 1582 AQPALFALEVALFELVSSWGVRADVLLGHSIGELAAAYVAGVWSLADACRIVAARGRLMQ 1641 Query: 751 ALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRV 810 ALP GG M AV+A E EL L G VSVAAVNGP S+VLSG E V+ + A QGRR Sbjct: 1642 ALPEGGAMVAVEAAEDELPDLPG-GVSVAAVNGPRSLVLSGDEEPVTALAQAFAEQGRRT 1700 Query: 811 RRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHI 870 ++L VSHAFHS MEPML +F V P IPV+SNVTG++ +++ + YWVRH+ Sbjct: 1701 KQLTVSHAFHSARMEPMLAEFAETLAAVEFRPPRIPVVSNVTGEMAGDEFTTPAYWVRHV 1760 Query: 871 REAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRPEPFX 928 REAVRFAD V AH+AG R++E+GP G LT+L ++ A V AVP LR D+PE Sbjct: 1761 REAVRFADGVGAAHAAGVRRYLELGPDGTLTTLAHDTAHDAGRDVAAVPALRGDQPETRT 1820 Query: 929 XXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 DW + A G + LPTYAF H R+WL Sbjct: 1821 VVTAVGRLYATGLTVDWPAFFAPYGARPTELPTYAFQHRRYWL 1863 Score = 642 bits (1656), Expect = 0.0 Identities = 403/1008 (39%), Positives = 520/1008 (51%), Gaps = 47/1008 (4%) Query: 1123 MGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVS 1182 M CR PG + PA+ L+ +G D +G P DR + R GGF+ Sbjct: 1 MACRLPGA-AGPAEFLALLRNGEDAVGAAPGDRRYA----------------PRRGGFLD 43 Query: 1183 DVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDG 1242 V +FD GFFGISP EA AMDPQQRL+LE SWEALEDAGI P L GS GVFVG D Sbjct: 44 SVDEFDAGFFGISPREAAAMDPQQRLVLELSWEALEDAGIPPARLGGSGAGVFVGAIADD 103 Query: 1243 YGL-----GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANS 1297 Y G A TG + + R+SY LGL GP+ +VD+ SSSLVA+HLAA S Sbjct: 104 YATLSRAAGADAATPQTTTGLNRGIIANRVSYTLGLRGPSFTVDSGQSSSLVAVHLAAES 163 Query: 1298 LRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQ 1357 LR GEC +ALAGG ++ + R L+ DG C F A+G EG G++VL+ Sbjct: 164 LRRGECSVALAGGVNLILAEDSTVAVERFGALSPDGYCYTFDARANGYVRGEGGGVVVLK 223 Query: 1358 RLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVE 1417 L+DA G + ILAGSAVN DG GLT P Q+ V++AA AGI+ A V VE Sbjct: 224 PLADAIADGDDIHCILAGSAVNNDGGGEGLTVPDRAGQEAVLTAAYEQAGISPAAVGYVE 283 Query: 1418 AHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMR 1477 HGTGT GDP+EA A+ A G PL +GS+K+N+GH + AAG+AG++K V A+R Sbjct: 284 LHGTGTPTGDPVEAAAVGAVLGAGRPAGQPLLVGSVKTNIGHLEGAAGIAGLLKAVLAVR 343 Query: 1478 HQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXX 1537 H+ +PATLH P+ + + + + T WP G P GVSSFG+ GTN H Sbjct: 344 HREIPATLHHASPNPAIPMAELGIGVNTALTPWPEQAG-PLVVGVSSFGMGGTNCHVVLT 402 Query: 1538 XXXXXXXXXXXXXG-------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVG 1590 P L +VS R + AQA +L + + L DV Sbjct: 403 EPAGYDAAARPATAGIRPAGTPAPL--LVSGRDEQALRAQARKLRDHLDTHPGLPLRDVA 460 Query: 1591 YSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGA 1650 ++L R+ RAV++ A R+++ AGLA + +G PG + G PG FVF GQG+ Sbjct: 461 HTLAAARAPLARRAVLLAADREDVSAGLARLADGTPGADLVRGTVSPGA-LAFVFTGQGS 519 Query: 1651 QWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGAD----AELLNTTEFAQPA 1706 Q GM EL LD L RPLR+V++ A+ A LL+ TEF QPA Sbjct: 520 QRPGMTAELYRTSAEYAAALDEVCASLDPWLRRPLRDVLFAAEGSDEAALLDRTEFTQPA 579 Query: 1707 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 1766 LFAVEVAL+R E G+ P ++GHSVGEL+AAHV+G RGRLMQ P Sbjct: 580 LFAVEVALFRYAEHCGLTPRFLLGHSVGELAAAHVAGVLSLADACTLVAARGRLMQDRPA 639 Query: 1767 GGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLA 1826 G M +VQA E EL P + E V++AA+NGP S V++G +AV V AA+GR+ +RL Sbjct: 640 TGAMVSVQATEDELAPFVSESVTLAALNGPASTVIAGDEDAVLAVAAHWAARGRKTKRLR 699 Query: 1827 VSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAE-DYGSADYWVRHIREA 1885 VSHAFHS M+ ML +FR +A + G P IP++SN TG L+ E D S +YWVRH R A Sbjct: 700 VSHAFHSPHMDGMLTEFRRIAAGLTFGAPRIPIVSNETGTLLTEADARSPEYWVRHARAA 759 Query: 1886 VRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLR-KDRPEPFXXXXX 1944 VRF D V G T +E+GP G L+++ + L V VP LR +DR EP Sbjct: 760 VRFLDGVRLLEDQGVTTLLELGPDGVLSAMARDCLRDAGTVCVPLLRGRDRTEPEALLAA 819 Query: 1945 XXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADR--------FXXXXXXXXX 1996 DW G +RV LPTYAF R WL + Sbjct: 820 LAGLYVRGVPMDWERTATEAGARRVPLPTYAFQRRRHWLPEPSASASRPVVNGGGHAGQA 879 Query: 1997 XXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLD 2056 R + + + L +V + TA VLG + Sbjct: 880 GHAGQAGRAGQAGHAGHDGEPAPAVRDRTTPELVRDRTTLELVRDATAQVLGHASPDDVA 939 Query: 2057 AGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHL 2104 +AF + G +SL EL RL TG + T FD+PTP LA L Sbjct: 940 THEAFRELGFSSLMLAELGERLTEATGRRVPTTLLFDHPTPDALARRL 987 Score = 551 bits (1419), Expect = e-154 Identities = 374/982 (38%), Positives = 512/982 (52%), Gaps = 31/982 (3%) Query: 10 ALQEWFTHYIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWD 68 AL + + +AA G + V D R LG S+ + L+ G +P ++D Sbjct: 2372 ALADLVSTEVAAVLGLPPTDRVREDTTFRALGFDSLIGVEFRNRLAAATGRRLPPSLIFD 2431 Query: 69 NPSAHDVIKSVLGG-DGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLW 127 +P+ +++ + G DG+ + + A ++P+ ++ ACRF G V LW Sbjct: 2432 HPTPGRLVEHLAAGLDGTGPNTAGEERVAPARTH--DDPVVIVSAACRFPGGVTTPEELW 2489 Query: 128 DFLAEKKSAITEYPARRLGAAAADWLGDEQE----TIY---GCFLEDVEGFDNKFFDIPP 180 + + AI +PA R D L D T Y G FL DV FD FF I P Sbjct: 2490 QLVLDGGDAIGPFPADR--GWDLDRLYDPDPGNPGTSYVREGGFLTDVADFDAAFFGISP 2547 Query: 181 DEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTI 240 EA MDPQQRLLLETSW ALE AGI+P +L S TGVFVG + DY LL + + Sbjct: 2548 REALAMDPQQRLLLETSWEALERAGIVPASLAGSRTGVFVGSNGQDYATLLGESEVEGHV 2607 Query: 241 WDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTN 300 TG +SS+++ R++Y L + GP+L +DTACSSSLVA HLA ++L +GECDLA+ AG Sbjct: 2608 L--TGTASSVLSGRIAYTLGLEGPALTVDTACSSSLVALHLAVQALNAGECDLALAAGVT 2665 Query: 301 VLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAV 360 V+ SPE++ F +S G C+AF ADG GEG G V+LERLSDARR G VL V Sbjct: 2666 VMSSPEIFVEFSRQRGLSADGRCKAFGPDADGTGWGEGVGTVLLERLSDARRLGHDVLGV 2725 Query: 361 LTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAH 420 + G+AVNQDG SNG+ APN AQ V+ A A P+++D VEAHGTGT +GD IEA Sbjct: 2726 VRGTAVNQDGASNGLSAPNGPAQQRVIRQALADAGCVPSDVDAVEAHGTGTRLGDPIEAQ 2785 Query: 421 ALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNP 480 AL +GR R A +PL +GS+K NIGH + AAG+AG++KT+ ++ GQL + P P Sbjct: 2786 ALLATYGRDRPADRPLWLGSVKSNIGHTQAAAGMAGVLKTLSAMRHGQLPRTLHAARPTP 2845 Query: 481 NIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP 540 + + E + ++ E + WPA RPRRAGVS+FG GTNAH P Sbjct: 2846 KVDWTEGAVELLTETRPWPATGARPRRAGVSAFGVSGTNAHVILEQAPAPQPARPAVLPP 2905 Query: 541 GV----LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVG 596 + + WV++A++ + AQA RL + E +VG SLVTTR+ + RAV++G Sbjct: 2906 LLNSPSVPWVLTAKSEEALAAQADRLSARL---PEAAPAEVGRSLVTTRATWPERAVLIG 2962 Query: 597 AGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXX 656 G AGL + G V G A G+ VFVFPGQGAQW GM L P Sbjct: 2963 DGSPHFAAGLGALAGGAGDPRVVRGTADTRGRVVFVFPGQGAQWAGMAARLWESSPVFAQ 3022 Query: 657 XXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAVEVALYRLLESWGMRPGL 715 L R L EV+ DA L+ + QPA +AV V+L L + G+ P Sbjct: 3023 WMDRCAEVLARLTDWSLTEVIHETQDAPGLDRVDVVQPASWAVSVSLAGLWRACGVEPAA 3082 Query: 716 VMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLM-QALPGGGVMYAVQAGEQELRPLLGE 774 V+GHS GE++AA V+G +R RL+ + L G G M +V + + Sbjct: 3083 VVGHSQGEIAAACVAGGLSLEDGAALVTLRSRLIAEELSGHGGMVSVALSPADTAERIAR 3142 Query: 775 ---QVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQF 831 + VAA N S V+SG EA++ ++ A+G R RR+ V +A HS +E + Q Sbjct: 3143 WNGGICVAANNSRRSTVVSGEPEALAELLAECEAEGVRARRIPVDYASHSAQVERIERQL 3202 Query: 832 RAVADEVYAGRPA-IPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATR 890 +A V A RP IP S TG + ADYW R++R V F + G Sbjct: 3203 TELAAGV-APRPGDIPFHSTTTGGPLDTTGLDADYWYRNLRRPVLFGPVTEELLAQGHDV 3261 Query: 891 FVEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASV 948 F+E+ P L +++++ + AV +LR+D P DW +V Sbjct: 3262 FLEMSPHPVLVPAVQDAVDATGTTAAAVGSLRRDDGGPERFTLSLAEAFVRGAPVDWTAV 3321 Query: 949 LAGCGGQRVGLPTYAFAHERFW 970 L G +RV LPTY F RFW Sbjct: 3322 LGTSGARRVELPTYPFQRGRFW 3343 Score = 88.2 bits (217), Expect = 1e-14 Identities = 51/107 (47%), Positives = 63/107 (58%), Gaps = 3/107 (2%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL LS AE+ VL +V EHTA VLG A +D QAF G SL+AVELRNRL+T Sbjct: 5979 RLAALSPAERHRLVLDLVREHTAGVLGHGSADDIDPDQAFKTLGFDSLTAVELRNRLRTA 6038 Query: 2082 TGVTLSATTAFDYPTPTQLADHLL---SHLHHQNPTGATPELDRVDA 2125 T +T+ AT FD+PTP L HLL + H EL+R++A Sbjct: 6039 TSLTVPATLVFDHPTPAALTAHLLELAAPPEHDPVLQVLGELERLEA 6085 Score = 87.0 bits (214), Expect = 3e-14 Identities = 46/84 (54%), Positives = 54/84 (64%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL LS AE+ VL +V EHTA VLG A +D QAF G SL+AVELRNRL+T Sbjct: 5979 RLAALSPAERHRLVLDLVREHTAGVLGHGSADDIDPDQAFKTLGFDSLTAVELRNRLRTA 6038 Query: 1070 TGVTLSATTAFDYPTPTQLADHLL 1093 T +T+ AT FD+PTP L HLL Sbjct: 6039 TSLTVPATLVFDHPTPAALTAHLL 6062 Score = 72.0 bits (175), Expect = 1e-09 Identities = 78/270 (28%), Positives = 106/270 (39%), Gaps = 39/270 (14%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL G +D E++ +L +V A LG GA + + F D G SL+AV+LRNRL Sbjct: 3882 RLAGSTDGERERELLDLVRTAAALALGHRGAEAITPSKPFKDLGFDSLTAVDLRNRLTAA 3941 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDAL-TDLFLQTCDAGRDD 2140 TGV L AT FD+PTP A L + L DAL T A D Sbjct: 3942 TGVRLPATLVFDHPTPLAAAVELRTRLFGG------------DALPTSAGSVAPTAAEAD 3989 Query: 2141 DGWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDVAVV------CLPTLTVLSSPHA 2194 D IVA+A T+ P++ W L+A G+ + + S Sbjct: 3990 DPVVIVAMACRFPGEATS--PEKLWD---LIAAGKDGIGDFPADRGWSVAADAAFSQTGG 4044 Query: 2195 YL-DVARAMAGRHSVHALSLPGFDPDDALPQDRE-----------VVLEGAAQAILHAVG 2242 +L DVA AG + DP L + + L G+ + G Sbjct: 4045 FLPDVAEFDAGFFGISPREALAMDPQQRLLLETSWEALERAGVDALKLRGSRTGVFVGAG 4104 Query: 2243 DHPHLVLAGYSSGG---VLAHALGSYLAER 2269 H + L GG L A+GS L+ R Sbjct: 4105 SHDYGTLLTSLEGGQDYALTGAVGSVLSGR 4134 Score = 58.5 bits (140), Expect = 1e-05 Identities = 45/138 (32%), Positives = 59/138 (42%), Gaps = 12/138 (8%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL+ + A+ +V AAVLG ++ F G SL VE RNRL Sbjct: 2360 RLGGLTGDALRQALADLVSTEVAAVLGLPPTDRVREDTTFRALGFDSLIGVEFRNRLAAA 2419 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 TG L + FD+PTP +L +HL + L P A E + A DD Sbjct: 2420 TGRRLPPSLIFDHPTPGRLVEHLAAGLDGTGPNTAGEE------------RVAPARTHDD 2467 Query: 2142 GWQIVALAANGRERMTTP 2159 IV+ A +TTP Sbjct: 2468 PVVIVSAACRFPGGVTTP 2485 >tr|Q0ILD4|Q0ILD4_9ACTO Tax_Id=204925 (nlmA1)SubName: Full=NlmA1;[Streptomyces nanchangensis] Length = 6148 Score = 1517 bits (3928), Expect = 0.0 Identities = 903/1894 (47%), Positives = 1115/1894 (58%), Gaps = 59/1894 (3%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCF 164 +PIAV+GMACR G GP AE + AI +GAAA D G F Sbjct: 18 QPIAVVGMACRLPG---AAGP-----AEFR-AILRSGTEAVGAAAPD---RPYAPPRGGF 65 Query: 165 LEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSS 224 L+ V+ FD FF + P EAA+MDPQQRL+LE W ALE +GI+P L S GVFVG + Sbjct: 66 LDSVDRFDAGFFGVSPREAAVMDPQQRLMLELCWEALEDSGIVPARLDGSDAGVFVGAIT 125 Query: 225 TDYVRLLFPGG-RKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLAR 283 DY L G T +TG + +IANR+SY L + GPS +D+ SSSLVA HLA Sbjct: 126 DDYAVLSRAAGVDAATPETSTGLNRGMIANRVSYRLGLRGPSFTVDSGQSSSLVAVHLAT 185 Query: 284 KSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVV 343 +SL GEC LA+ G N++++ + + G +SP G C FDARA+G VRGEG GVVV Sbjct: 186 ESLRRGECSLALAGGVNLILAEDSTAAVERFGALSPDGRCYTFDARANGYVRGEGGGVVV 245 Query: 344 LERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDY 403 L+RL+DA G +L VL GSAVN DG G+ P+ + Q +VL +A + A I P + Y Sbjct: 246 LKRLTDAVADGDDILCVLAGSAVNNDGGGEGLTVPDRQGQEAVLTAAYEQAGISPNAVGY 305 Query: 404 VEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLM 463 VE HGTGT GD +EA A+G V G GR A +PL++GS+K NIGHLEGAAGIAGL+K VL Sbjct: 306 VELHGTGTPAGDPVEAAAVGAVLGAGRSAEQPLLVGSVKTNIGHLEGAAGIAGLLKAVLT 365 Query: 464 LQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXX 523 ++ ++ S F P+ IP ELGL+V + W + G P GVSSFG GGTN H Sbjct: 366 VRHREIHASLNFTTPSTRIPMTELGLSVNTALRPWLSEAG-PLIVGVSSFGMGGTNCHVV 424 Query: 524 XXXXXXXXXXXXXXXGPGVLA--WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSL 581 P A +++ R + QA L + L DV ++L Sbjct: 425 LTEWHGVAPVTAPGIRPNGTAVPLLITGRDEQALRDQAHHLGRHLDEHGPLRLKDVAHTL 484 Query: 582 VTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWL 641 R+ FEHRAV++ ++ GLA + +G PG + A F+F GQG+Q Sbjct: 485 AAGRTAFEHRAVLLVREPQDMTDGLARLADGTPGPDLVRATATCSS-LAFLFTGQGSQRP 543 Query: 642 GMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGAD----AELLNTTEFAQPALFA 697 GM EL LD L PLREV++ A+ A LL+ TEF QPALFA Sbjct: 544 GMTAELYQSSSEYAAALDEVCAHLDPQLRVPLREVLFAAEGTAEAVLLDRTEFTQPALFA 603 Query: 698 VEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGV 757 VEVAL+R E G+ P L++GHSVGEL+AAHV+G RGRLMQA P G Sbjct: 604 VEVALFRFAEHCGLVPRLLLGHSVGELAAAHVAGVLSLADACSLVAARGRLMQAQPATGA 663 Query: 758 MYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSH 817 M A+QA E+EL P L E V+ AA+NGP S VL+G EAV + AA+GRR +RL VSH Sbjct: 664 MAAIQATEKELAPFLDESVAAAALNGPASTVLAGDEEAVLAIAAHWAAKGRRTKRLRVSH 723 Query: 818 AFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAE-DYGSADYWVRHIREAVRF 876 AFHS M+ MLE+F VA ++ P +P++SN TG L+ E + S +YWVR R VRF Sbjct: 724 AFHSPHMDGMLEEFHRVAGQLTFEAPRVPIVSNETGALLTEAEACSPEYWVRQARVTVRF 783 Query: 877 ADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXX 936 D V G T +E+GP G L+SL + L V V+VP LR R EP Sbjct: 784 LDGVRLLEEQGVTTLLELGPDGTLSSLARDCLRGVDAVSVPLLR-GRTEPEEVVAALATL 842 Query: 937 XXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXX 996 W + G +RV LPTY F R WL D Sbjct: 843 QVRGVPMHWERLATEEGARRVPLPTYPFQRRRHWLPDLVAQDSVPAPGRAAGQRSRPVNE 902 Query: 997 XXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTS 1056 D + V A V A VLG D + A F + GL+S Sbjct: 903 PAPSAHAPR---------GDRTMRETVRAAV----ALVLGHDSPDDIPAHTTFRELGLSS 949 Query: 1057 LSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDE 1116 L E+ RL TG + T FD+PTP L L S R A + D+ Sbjct: 950 LMLAEVGERLTEATGRRVPTTLLFDHPTPDALVRELTSG--GAERPAALTTAPSAAHADD 1007 Query: 1117 PIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTR 1176 P+ +VGM CR PGG+ SP + WQ +A+ GD I P DRGW A+ + Sbjct: 1008 PVVVVGMACRLPGGIRSPEEFWQFMAADGDAISPLPTDRGW-----------AVSGDFPA 1056 Query: 1177 HGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFV 1236 GGF++DVA FD FFGISP EALAMDPQQRLLLETSWEALE AG+D +LRGS TGVFV Sbjct: 1057 EGGFLADVAGFDAAFFGISPREALAMDPQQRLLLETSWEALERAGVDALSLRGSRTGVFV 1116 Query: 1237 GIYGDGYGLGT---SQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHL 1293 G YG SQA + TG SV SGR++Y LGL GPA++VDTACSSSLVALHL Sbjct: 1117 GASPSEYGPRLHEPSQADGHVLTGTAPSVLSGRVAYVLGLEGPALTVDTACSSSLVALHL 1176 Query: 1294 AANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGM 1353 AA +LR GECDLALAGG V+AT +F F+RQ GLA DGRCKAFAD ADGTG+ EG G+ Sbjct: 1177 AAQALRGGECDLALAGGVAVMATAGMFAEFARQGGLARDGRCKAFADGADGTGWGEGVGV 1236 Query: 1354 LVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADV 1413 LVL RLS+ARR G VLA+++GSAVN DGASNGLTAP+GP+QQRVI AL+ AG++ DV Sbjct: 1237 LVLSRLSEARRCGYTVLAVVSGSAVNSDGASNGLTAPNGPSQQRVIRQALASAGLSPGDV 1296 Query: 1414 DVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMV 1473 DVVEAHGTGT LGDPIEAQALLATYG++ PL++GS+KSN+GH QAAAGVAGVIK V Sbjct: 1297 DVVEAHGTGTALGDPIEAQALLATYGQERGAGRPLYVGSVKSNIGHVQAAAGVAGVIKSV 1356 Query: 1474 EAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH 1533 A+R+ +LP TLH+D PS VDWS G V+LLTEA EW A GRPRR GVS+FG+SGTNAH Sbjct: 1357 LALRYGVLPRTLHVDVPSREVDWSAGAVELLTEAVEWLA-GGRPRRVGVSAFGISGTNAH 1415 Query: 1534 XXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSL 1593 GV+ WVVSAR+ G+ AQA RL+E V G L DVG+SL Sbjct: 1416 VILEEAPEGVEESAAGEVAGVVPWVVSARSEEGLRAQAARLVEHVVGGSGLGPVDVGWSL 1475 Query: 1594 VTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWL 1653 +R++ EHRAVV+G +EL+AGL + +G G GV GVA GG T +F GQGAQ + Sbjct: 1476 ARSRAVLEHRAVVLGGDGEELVAGLRALCDGVLGPGVVRGVAGDGG-TALLFTGQGAQRV 1534 Query: 1654 GMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVA 1713 GMGREL +P + L LR VV+G +++ TE+AQPALFA+EVA Sbjct: 1535 GMGRELYEAFPVFAAAFDAVCAGFEGMLPGSLRGVVFGDGGGVVDRTEWAQPALFALEVA 1594 Query: 1714 LYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAV 1773 L+ L+ SWG+R +++GHSVGEL AAHV+G RGRLMQALP GG M AV Sbjct: 1595 LFELVVSWGVRADVLVGHSVGELVAAHVAGVWSLADACRVVAARGRLMQALPVGGAMVAV 1654 Query: 1774 QAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHS 1833 + GE EL P+L E VSVAAVNGP S+VLSG V + RLA +GR RRL VSHAFHS Sbjct: 1655 RVGEGEL-PVLPEGVSVAAVNGPRSLVLSGDEGPVLELAARLAGEGRDTRRLRVSHAFHS 1713 Query: 1834 VLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVC 1893 MEPML +F V V P IPVISNVTG++ E+ + +YWVR +REAVRFAD V Sbjct: 1714 ARMEPMLAEFAQVLAAVEFRAPRIPVISNVTGEVAGEELTTPEYWVRQVREAVRFADGVN 1773 Query: 1894 FAHSAGATRFVEVGPAGGLTSLIEESLAQV----SVVAVPTLRKDRPEPFXXXXXXXXXX 1949 AH +G R++E+GP G LTSL + LA+ V VP LR D+PE Sbjct: 1774 TAHGSGVRRYLELGPDGVLTSLAHDILAEQGIDRDVAVVPALRHDQPESRTLLTALGQLH 1833 Query: 1950 XXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 WA+ LA G + V LPTYAF H R+WL Sbjct: 1834 TTGMDVGWAAFLAPYGARTVELPTYAFEHHRYWL 1867 Score = 960 bits (2481), Expect = 0.0 Identities = 531/982 (54%), Positives = 646/982 (65%), Gaps = 21/982 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L D E+ +L +V A LG G + + F + G SL+AV+LRNRL Sbjct: 3895 RLAQLPDGERDRELLDLVRNAAALALGHTGTEPITPSKPFKELGFDSLTAVDLRNRLTAA 3954 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNR----SAPAAAVRTRVRIDEPIAIVGMGC 1125 TG+ L AT FDYPTP AD L + L + +APA + R D+P+ +V M C Sbjct: 3955 TGLRLPATLVFDYPTPRAAADALRAVLFAADMPVDTAAPARSASARPADDDPVVVVAMAC 4014 Query: 1126 RYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVA 1185 RYPGG ++P + W L+A+G D IG FP DRGW+I G ++R GGF++DVA Sbjct: 4015 RYPGGATTPEKFWDLIAAGEDGIGGFPTDRGWEI---------GPGAAFSRTGGFLADVA 4065 Query: 1186 DFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGL 1245 FD FFGISP EALAMDPQQRLLLETSWEALE AG+D +LRGS TGVFVG YG Sbjct: 4066 GFDAAFFGISPREALAMDPQQRLLLETSWEALERAGVDALSLRGSRTGVFVGASPSEYGT 4125 Query: 1246 GTSQ---AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGE 1302 + Q YA TG + SV SGR++Y LGL GPA++VDTACSSSLVALHLAA +LR GE Sbjct: 4126 LVASLEGGQDYALTGAVGSVLSGRVAYVLGLEGPALTVDTACSSSLVALHLAAQALRGGE 4185 Query: 1303 CDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDA 1362 CDLALAGG V+ATP+ F F+RQ GLA DGRCKAFAD ADGTG+ EG G+LVL RLS+A Sbjct: 4186 CDLALAGGVAVMATPNAFDAFARQGGLARDGRCKAFADGADGTGWGEGVGVLVLSRLSEA 4245 Query: 1363 RRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTG 1422 RR G VLA+++GSAVN DGASNGLTAP+GP+QQRVI AL+ AG++ DVDVVEAHGTG Sbjct: 4246 RRCGYTVLAVVSGSAVNSDGASNGLTAPNGPSQQRVIRQALASAGLSPGDVDVVEAHGTG 4305 Query: 1423 TRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLP 1482 T LGDPIEAQALLATYG++ PL++GS+KSN+GH QAAAGVAGVIK V A+R+ +LP Sbjct: 4306 TALGDPIEAQALLATYGQERGAGRPLYVGSVKSNIGHVQAAAGVAGVIKSVLALRYGVLP 4365 Query: 1483 ATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXX 1542 TLH+D PS VDWS G V+LLTEA EWPA GRPRR GVS+FG+SGTNAH Sbjct: 4366 RTLHVDVPSREVDWSAGAVELLTEAVEWPA-GGRPRRVGVSAFGISGTNAHVILEEAPEG 4424 Query: 1543 XXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEH 1602 GV+ WVVSAR+ G+ AQA RL+E V G L DVG+SL +R++ EH Sbjct: 4425 VEESAAGEVAGVVPWVVSARSEEGLRAQAARLVEHVVGGSGLGPVDVGWSLARSRAVLEH 4484 Query: 1603 RAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAG 1662 RAVV+G +EL+AGL + +G G GV GVA GG T +F GQGAQ +GMGREL Sbjct: 4485 RAVVLGGDGEELVAGLRALCDGVLGPGVVRGVAGDGG-TALLFTGQGAQRVGMGRELYEA 4543 Query: 1663 YPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWG 1722 +P + L LR VV+G +++ TE+AQPALFA+EVAL+ L+ SWG Sbjct: 4544 FPVFAAAFDAVCAGFEGMLPGSLRGVVFGDGGGVVDRTEWAQPALFALEVALFELVVSWG 4603 Query: 1723 MRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRP 1782 +R +++GHSVGEL AAHV+G RGRLMQALP GG M AV+ GE EL P Sbjct: 4604 VRADVLVGHSVGELVAAHVAGVWSLADACRVVAARGRLMQALPVGGAMVAVRVGEGEL-P 4662 Query: 1783 LLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQ 1842 +L E VSVAAVNGP S+VLSG V + RLA +GR RRL VSHAFHS MEPML + Sbjct: 4663 VLPEGVSVAAVNGPRSLVLSGDEGPVLELAARLAGEGRDTRRLRVSHAFHSARMEPMLAE 4722 Query: 1843 FRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATR 1902 F V V P IPVISNVTG++ E+ + +YWVR +REAVRFAD V A G + Sbjct: 4723 FAQVLAAVEFRAPRIPVISNVTGEVAGEELTTPEYWVRQVREAVRFADGVNTALGRGVDK 4782 Query: 1903 FVEVGPAGGLTSLIEESLAQVS--VVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASV 1960 F+E+GP+G LT++ EE + V VP LR RPE W + Sbjct: 4783 FLELGPSGPLTAMAEEVIEHTGTRAVCVPVLRAGRPEDATLLHALAAVFVTGATVGWTAP 4842 Query: 1961 LAGCGGQRVGLPTYAFAHERFW 1982 LAG G + V LPTYAF H+R+W Sbjct: 4843 LAGTGARAVDLPTYAFQHKRYW 4864 Score = 790 bits (2039), Expect = 0.0 Identities = 471/993 (47%), Positives = 590/993 (59%), Gaps = 27/993 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL+ E + A+ MV AAVLG ++ + F G SL VE RNRL Sbjct: 2371 RLAGLAGDELRQALDDMVTVEVAAVLGFRAKDRVPTDRTFKSLGFDSLIGVEFRNRLAAA 2430 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSA-----PAAAVRTRVRIDEPIAIVGMG 1124 G L + +D+PTP +L +HL + + ++ + P A RT D+P+ IV Sbjct: 2431 LGRRLPPSLIYDHPTPGRLVEHLAAGVDGGDQPSTVGGRPVAPTRTH---DDPVVIVSAA 2487 Query: 1125 CRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDV 1184 CR+PGGV +P LWQLV GGD IG FP DRGWD++RL+DPDP A G +Y R GGF++ V Sbjct: 2488 CRFPGGVRTPEDLWQLVLDGGDAIGPFPVDRGWDLDRLYDPDPGASGTSYVREGGFLTGV 2547 Query: 1185 ADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG 1244 ADFD FFGISP EALAMDPQQRLLLETSWEALE AGI P +L GS TGVFVG G Y Sbjct: 2548 ADFDAVFFGISPREALAMDPQQRLLLETSWEALERAGIVPGSLAGSRTGVFVGSNGQDYA 2607 Query: 1245 --LGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGE 1302 L +S + + TG +SV SGRI+Y LGL GPA++VDTACSSSLVALHLA +L +GE Sbjct: 2608 NLLHSSDVEGHVLTGTASSVLSGRIAYTLGLEGPALTVDTACSSSLVALHLAVQALSSGE 2667 Query: 1303 CDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDA 1362 CDLALAGG TV++ IF+ FSRQRGL+ DGRCKAF ADGTG++EG G +VL+RLSDA Sbjct: 2668 CDLALAGGVTVMSGSDIFVEFSRQRGLSADGRCKAFGPDADGTGWAEGVGTVVLERLSDA 2727 Query: 1363 RRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTG 1422 RR G VL ++ G+AVNQDGASNGL+APSG AQQRVI AL+DAG +DVD VEAHGTG Sbjct: 2728 RRLGHEVLGVVRGTAVNQDGASNGLSAPSGRAQQRVIRQALADAGCAPSDVDAVEAHGTG 2787 Query: 1423 TRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLP 1482 TRLGDPIEAQALL TYG+D D PL+LGSIKSN+GH+QAAAG+AGV+KM+ A+RH LP Sbjct: 2788 TRLGDPIEAQALLTTYGQDRPADRPLYLGSIKSNIGHAQAAAGLAGVLKMLFALRHGQLP 2847 Query: 1483 ATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH------XXX 1536 TLH +P+ VDWS G V LLTE R WPA V RPRRAGVS+FGVSGTNAH Sbjct: 2848 KTLHAPRPTPEVDWSEGAVALLTEDRPWPA-VDRPRRAGVSAFGVSGTNAHVILEQAPPS 2906 Query: 1537 XXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTT 1596 V WV++AR+ +GA A RL E A DV SLVTT Sbjct: 2907 AASDPAPTVRPPAVDSSVQPWVLTARSGEALGALADRLRE---AAPGAVPADVARSLVTT 2963 Query: 1597 RSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMG 1656 R+++ RAV++ GRDE +GLA + G V G A G+ VFVFPGQGAQW GM Sbjct: 2964 RTIWAERAVLLADGRDEYASGLAALATGEGDARVVRGTADTRGRVVFVFPGQGAQWAGMA 3023 Query: 1657 RELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGAD-AELLNTTEFAQPALFAVEVALY 1715 L P L L EV+ AD A L+ + QPA +AV V+L Sbjct: 3024 ARLWESSPEFARWMDRCDKALGDLTDWSLAEVIHQADGAPGLDRVDVLQPASWAVSVSLA 3083 Query: 1716 RLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLM-QALPGGGVMYAV- 1773 L S G+ P V+GHS GE++AA V+G +R RL+ + L G G M +V Sbjct: 3084 ALWRSCGVEPAAVVGHSQGEIAAACVAGALSLEDGAMLVTLRSRLIREELSGHGGMMSVA 3143 Query: 1774 --QAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAF 1831 AG + ++ VAA N S V++G A++ ++ A G R RR+ V +A Sbjct: 3144 LSPAGTADRIACWEGRICVAAHNSRRSTVVAGEPAALAELLAACEADGIRARRIPVDYAS 3203 Query: 1832 HSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADS 1891 HS +E + + +A + + IP S VTG + A YW R++R+ V F Sbjct: 3204 HSPQVERIERKLTELAAGIVSRSSEIPFHSTVTGTRLHTTGLDAGYWYRNLRKPVLFGPV 3263 Query: 1892 VCFAHSAGATRFVEVGPAGGLTSLIEESLAQV--SVVAVPTLRKDRPEPFXXXXXXXXXX 1949 + G F+E+ P L ++E+ V + AV +LR+ P Sbjct: 3264 TEELLTQGHDVFLEMSPHPVLVPAVQEASDAVTATAAAVGSLRRGDGGPERFLLSLAEAF 3323 Query: 1950 XXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 DWA+VL G G + V LPTY F RFW Sbjct: 3324 VRGAHVDWAAVLGGTGTRLVELPTYPFQRTRFW 3356 Score = 740 bits (1910), Expect = 0.0 Identities = 438/964 (45%), Positives = 579/964 (60%), Gaps = 31/964 (3%) Query: 19 IAARTGCDSAEVNLDLP----LRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHD 74 +A G DS + D+P R+LGL S+ + + L++ G VP ++D+P+ Sbjct: 924 VALVLGHDSPD---DIPAHTTFRELGLSSLMLAEVGERLTEATGRRVPTTLLFDHPTPDA 980 Query: 75 VIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKK 134 +++ + G G++R A T + ++P+ V+GMACR G + W F+A Sbjct: 981 LVRELTSG-GAERPAALTTAPSA---AHADDPVVVVGMACRLPGGIRSPEEFWQFMAADG 1036 Query: 135 SAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLL 194 AI+ P R A + D+ + G FL DV GFD FF I P EA MDPQQRLLL Sbjct: 1037 DAISPLPTDRGWAVSGDFPAE------GGFLADVAGFDAAFFGISPREALAMDPQQRLLL 1090 Query: 195 ETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDN---TGGSSSII 251 ETSW ALE AG+ +L+ S TGVFVG S ++Y P +P+ D TG + S++ Sbjct: 1091 ETSWEALERAGVDALSLRGSRTGVFVGASPSEYG----PRLHEPSQADGHVLTGTAPSVL 1146 Query: 252 ANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGF 311 + R++Y L + GP+L +DTACSSSLVA HLA ++L GECDLA+ G V+ + ++ F Sbjct: 1147 SGRVAYVLGLEGPALTVDTACSSSLVALHLAAQALRGGECDLALAGGVAVMATAGMFAEF 1206 Query: 312 QEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGR 371 G ++ G C+AF ADG GEG GV+VL RLS+ARR G TVLAV++GSAVN DG Sbjct: 1207 ARQGGLARDGRCKAFADGADGTGWGEGVGVLVLSRLSEARRCGYTVLAVVSGSAVNSDGA 1266 Query: 372 SNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQ 431 SNG+ APN +Q V+ A A + P ++D VEAHGTGT++GD IEA AL +G+ R Sbjct: 1267 SNGLTAPNGPSQQRVIRQALASAGLSPGDVDVVEAHGTGTALGDPIEAQALLATYGQERG 1326 Query: 432 AAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAV 491 A +PL +GS+K NIGH++ AAG+AG+IK+VL L+ G L + +VP+ + ++ + + Sbjct: 1327 AGRPLYVGSVKSNIGHVQAAAGVAGVIKSVLALRYGVLPRTLHVDVPSREVDWSAGAVEL 1386 Query: 492 VEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSART 551 + E EW A GRPRR GVS+FG GTNAH GV+ WVVSAR+ Sbjct: 1387 LTEAVEWLA-GGRPRRVGVSAFGISGTNAHVILEEAPEGVEESAAGEVAGVVPWVVSARS 1445 Query: 552 AAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVE 611 G+ AQA RL+E V G L DVG+SL +R++ EHRAVV+G +EL+AGL + + Sbjct: 1446 EEGLRAQAARLVEHVVGGSGLGPVDVGWSLARSRAVLEHRAVVLGGDGEELVAGLRALCD 1505 Query: 612 GRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLAR 671 G G GV GVA GG T +F GQGAQ +GMGREL +P + L Sbjct: 1506 GVLGPGVVRGVAGDGG-TALLFTGQGAQRVGMGRELYEAFPVFAAAFDAVCAGFEGMLPG 1564 Query: 672 PLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSG 731 LR VV+G +++ TE+AQPALFA+EVAL+ L+ SWG+R +++GHSVGEL AAHV+G Sbjct: 1565 SLRGVVFGDGGGVVDRTEWAQPALFALEVALFELVVSWGVRADVLVGHSVGELVAAHVAG 1624 Query: 732 XXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSG 791 RGRLMQALP GG M AV+ GE EL P+L E VSVAAVNGP S+VLSG Sbjct: 1625 VWSLADACRVVAARGRLMQALPVGGAMVAVRVGEGEL-PVLPEGVSVAAVNGPRSLVLSG 1683 Query: 792 AREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNV 851 V + RLA +GR RRL VSHAFHS MEPML +F V V P IPVISNV Sbjct: 1684 DEGPVLELAARLAGEGRDTRRLRVSHAFHSARMEPMLAEFAQVLAAVEFRAPRIPVISNV 1743 Query: 852 TGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQV 911 TG++ E+ + +YWVR +REAVRFAD V AH +G R++E+GP G LTSL + LA+ Sbjct: 1744 TGEVAGEELTTPEYWVRQVREAVRFADGVNTAHGSGVRRYLELGPDGVLTSLAHDILAEQ 1803 Query: 912 ----SVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHE 967 V VP LR D+PE WA+ LA G + V LPTYAF H Sbjct: 1804 GIDRDVAVVPALRHDQPESRTLLTALGQLHTTGMDVGWAAFLAPYGARTVELPTYAFEHH 1863 Query: 968 RFWL 971 R+WL Sbjct: 1864 RYWL 1867 Score = 729 bits (1883), Expect = 0.0 Identities = 429/947 (45%), Positives = 565/947 (59%), Gaps = 26/947 (2%) Query: 35 PLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPS---AHDVIKSVLGGDGSQRSADS 91 P ++LG S+ + + L+ G+ +P V+D P+ A D +++VL + D+ Sbjct: 3933 PFKELGFDSLTAVDLRNRLTAATGLRLPATLVFDYPTPRAAADALRAVLFA--ADMPVDT 3990 Query: 92 DTGCAVLGNGPTNE-PIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARR---LGA 147 P ++ P+ V+ MACR+ G WD +A + I +P R +G Sbjct: 3991 AAPARSASARPADDDPVVVVAMACRYPGGATTPEKFWDLIAAGEDGIGGFPTDRGWEIGP 4050 Query: 148 AAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGIL 207 AA + G FL DV GFD FF I P EA MDPQQRLLLETSW ALE AG+ Sbjct: 4051 GAAF-------SRTGGFLADVAGFDAAFFGISPREALAMDPQQRLLLETSWEALERAGVD 4103 Query: 208 PKTLKLSHTGVFVGVSSTDYVRLL--FPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPS 265 +L+ S TGVFVG S ++Y L+ GG+ + TG S+++ R++Y L + GP+ Sbjct: 4104 ALSLRGSRTGVFVGASPSEYGTLVASLEGGQDYAL---TGAVGSVLSGRVAYVLGLEGPA 4160 Query: 266 LVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRA 325 L +DTACSSSLVA HLA ++L GECDLA+ G V+ +P + F G ++ G C+A Sbjct: 4161 LTVDTACSSSLVALHLAAQALRGGECDLALAGGVAVMATPNAFDAFARQGGLARDGRCKA 4220 Query: 326 FDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQIS 385 F ADG GEG GV+VL RLS+ARR G TVLAV++GSAVN DG SNG+ APN +Q Sbjct: 4221 FADGADGTGWGEGVGVLVLSRLSEARRCGYTVLAVVSGSAVNSDGASNGLTAPNGPSQQR 4280 Query: 386 VLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNI 445 V+ A A + P ++D VEAHGTGT++GD IEA AL +G+ R A +PL +GS+K NI Sbjct: 4281 VIRQALASAGLSPGDVDVVEAHGTGTALGDPIEAQALLATYGQERGAGRPLYVGSVKSNI 4340 Query: 446 GHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRP 505 GH++ AAG+AG+IK+VL L+ G L + +VP+ + ++ + ++ E EWPA GRP Sbjct: 4341 GHVQAAAGVAGVIKSVLALRYGVLPRTLHVDVPSREVDWSAGAVELLTEAVEWPA-GGRP 4399 Query: 506 RRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEF 565 RR GVS+FG GTNAH GV+ WVVSAR+ G+ AQA RL+E Sbjct: 4400 RRVGVSAFGISGTNAHVILEEAPEGVEESAAGEVAGVVPWVVSARSEEGLRAQAARLVEH 4459 Query: 566 VRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMP 625 V G L DVG+SL +R++ EHRAVV+G +EL+AGL + +G G GV GVA Sbjct: 4460 VVGGSGLGPVDVGWSLARSRAVLEHRAVVLGGDGEELVAGLRALCDGVLGPGVVRGVAGD 4519 Query: 626 GGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELL 685 GG T +F GQGAQ +GMGREL +P + L LR VV+G ++ Sbjct: 4520 GG-TALLFTGQGAQRVGMGRELYEAFPVFAAAFDAVCAGFEGMLPGSLRGVVFGDGGGVV 4578 Query: 686 NTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMR 745 + TE+AQPALFA+EVAL+ L+ SWG+R +++GHSVGEL AAHV+G R Sbjct: 4579 DRTEWAQPALFALEVALFELVVSWGVRADVLVGHSVGELVAAHVAGVWSLADACRVVAAR 4638 Query: 746 GRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAA 805 GRLMQALP GG M AV+ GE EL P+L E VSVAAVNGP S+VLSG V + RLA Sbjct: 4639 GRLMQALPVGGAMVAVRVGEGEL-PVLPEGVSVAAVNGPRSLVLSGDEGPVLELAARLAG 4697 Query: 806 QGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADY 865 +GR RRL VSHAFHS MEPML +F V V P IPVISNVTG++ E+ + +Y Sbjct: 4698 EGRDTRRLRVSHAFHSARMEPMLAEFAQVLAAVEFRAPRIPVISNVTGEVAGEELTTPEY 4757 Query: 866 WVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS--VVAVPTLRKDR 923 WVR +REAVRFAD V A G +F+E+GP+G LT++ EE + V VP LR R Sbjct: 4758 WVRQVREAVRFADGVNTALGRGVDKFLELGPSGPLTAMAEEVIEHTGTRAVCVPVLRAGR 4817 Query: 924 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 PE W + LAG G + V LPTYAF H+R+W Sbjct: 4818 PEDATLLHALAAVFVTGATVGWTAPLAGTGARAVDLPTYAFQHKRYW 4864 Score = 625 bits (1613), Expect = e-176 Identities = 399/1012 (39%), Positives = 517/1012 (51%), Gaps = 45/1012 (4%) Query: 1107 AVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPD 1166 A R +PIA+VGM CR PG + PA+ ++ SG + +G PDR + R Sbjct: 9 AAEFTARSAQPIAVVGMACRLPGA-AGPAEFRAILRSGTEAVGAAAPDRPYAPPR----- 62 Query: 1167 PDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQA 1226 GGF+ V FD GFFG+SP EA MDPQQRL+LE WEALED+GI P Sbjct: 63 -----------GGFLDSVDRFDAGFFGVSPREAAVMDPQQRLMLELCWEALEDSGIVPAR 111 Query: 1227 LRGSSTGVFVGIYGDGYGL-----GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVD 1281 L GS GVFVG D Y + G A TG + + R+SY LGL GP+ +VD Sbjct: 112 LDGSDAGVFVGAITDDYAVLSRAAGVDAATPETSTGLNRGMIANRVSYRLGLRGPSFTVD 171 Query: 1282 TACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADA 1341 + SSSLVA+HLA SLR GEC LALAGG ++ R L+ DGRC F Sbjct: 172 SGQSSSLVAVHLATESLRRGECSLALAGGVNLILAEDSTAAVERFGALSPDGRCYTFDAR 231 Query: 1342 ADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISA 1401 A+G EG G++VL+RL+DA G +L +LAGSAVN DG GLT P Q+ V++A Sbjct: 232 ANGYVRGEGGGVVVLKRLTDAVADGDDILCVLAGSAVNNDGGGEGLTVPDRQGQEAVLTA 291 Query: 1402 ALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQ 1461 A AGI+ V VE HGTGT GDP+EA A+ A G + + PL +GS+K+N+GH + Sbjct: 292 AYEQAGISPNAVGYVELHGTGTPAGDPVEAAAVGAVLGAGRSAEQPLLVGSVKTNIGHLE 351 Query: 1462 AAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAG 1521 AAG+AG++K V +RH+ + A+L+ PS + + + + T R W + G P G Sbjct: 352 GAAGIAGLLKAVLTVRHREIHASLNFTTPSTRIPMTELGLSVNTALRPWLSEAG-PLIVG 410 Query: 1522 VSSFGVSGTNAHXXXXXXXXXXXXXXXXXGPG--VLAWVVSARTAAGVGAQAGRLLEFVR 1579 VSSFG+ GTN H P + +++ R + QA L + Sbjct: 411 VSSFGMGGTNCHVVLTEWHGVAPVTAPGIRPNGTAVPLLITGRDEQALRDQAHHLGRHLD 470 Query: 1580 AGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGG 1639 L DV ++L R+ FEHRAV++ ++ GLA + +G PG + A Sbjct: 471 EHGPLRLKDVAHTLAAGRTAFEHRAVLLVREPQDMTDGLARLADGTPGPDLVRATA-TCS 529 Query: 1640 KTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG----ADAE 1695 F+F GQG+Q GM EL LD L PLREV++ A+A Sbjct: 530 SLAFLFTGQGSQRPGMTAELYQSSSEYAAALDEVCAHLDPQLRVPLREVLFAAEGTAEAV 589 Query: 1696 LLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXX 1755 LL+ TEF QPALFAVEVAL+R E G+ P L++GHSVGEL+AAHV+G Sbjct: 590 LLDRTEFTQPALFAVEVALFRFAEHCGLVPRLLLGHSVGELAAAHVAGVLSLADACSLVA 649 Query: 1756 MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRL 1815 RGRLMQA P G M A+QA E+EL P L E V+ AA+NGP S VL+G EAV + Sbjct: 650 ARGRLMQAQPATGAMAAIQATEKELAPFLDESVAAAALNGPASTVLAGDEEAVLAIAAHW 709 Query: 1816 AAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAE-DYGS 1874 AA+GRR +RL VSHAFHS M+ MLE+F VA ++ P +P++SN TG L+ E + S Sbjct: 710 AAKGRRTKRLRVSHAFHSPHMDGMLEEFHRVAGQLTFEAPRVPIVSNETGALLTEAEACS 769 Query: 1875 ADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKD 1934 +YWVR R VRF D V G T +E+GP G L+SL + L V V+VP LR Sbjct: 770 PEYWVRQARVTVRFLDGVRLLEEQGVTTLLELGPDGTLSSLARDCLRGVDAVSVPLLR-G 828 Query: 1935 RPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXX 1994 R EP W + G +RV LPTY F R WL D Sbjct: 829 RTEPEEVVAALATLQVRGVPMHWERLATEEGARRVPLPTYPFQRRRHWLPDLVAQDSVPA 888 Query: 1995 XXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQ 2054 D + V A V A VLG D Sbjct: 889 PGRAAGQRSRPVNEPAPSAHAPR---------GDRTMRETVRAAV----ALVLGHDSPDD 935 Query: 2055 LDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLS 2106 + A F + GL+SL E+ RL TG + T FD+PTP L L S Sbjct: 936 IPAHTTFRELGLSSLMLAEVGERLTEATGRRVPTTLLFDHPTPDALVRELTS 987 Score = 551 bits (1421), Expect = e-154 Identities = 370/986 (37%), Positives = 510/986 (51%), Gaps = 37/986 (3%) Query: 10 ALQEWFTHYIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWD 68 AL + T +AA G + + V D + LG S+ + L+ LG +P ++D Sbjct: 2383 ALDDMVTVEVAAVLGFRAKDRVPTDRTFKSLGFDSLIGVEFRNRLAAALGRRLPPSLIYD 2442 Query: 69 NPSAHDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWD 128 +P+ +++ + G + G V ++P+ ++ ACRF G V LW Sbjct: 2443 HPTPGRLVEHLAAGVDGGDQPSTVGGRPVAPTRTHDDPVVIVSAACRFPGGVRTPEDLWQ 2502 Query: 129 FLAEKKSAITEYPARR-----------LGAAAADWLGDEQETIYGCFLEDVEGFDNKFFD 177 + + AI +P R GA+ ++ + G FL V FD FF Sbjct: 2503 LVLDGGDAIGPFPVDRGWDLDRLYDPDPGASGTSYVRE------GGFLTGVADFDAVFFG 2556 Query: 178 IPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRK 237 I P EA MDPQQRLLLETSW ALE AGI+P +L S TGVFVG + DY LL + Sbjct: 2557 ISPREALAMDPQQRLLLETSWEALERAGIVPGSLAGSRTGVFVGSNGQDYANLLHSSDVE 2616 Query: 238 PTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVA 297 + TG +SS+++ R++Y L + GP+L +DTACSSSLVA HLA ++L+SGECDLA+ Sbjct: 2617 GHVL--TGTASSVLSGRIAYTLGLEGPALTVDTACSSSLVALHLAVQALSSGECDLALAG 2674 Query: 298 GTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTV 357 G V+ +++ F +S G C+AF ADG EG G VVLERLSDARR G V Sbjct: 2675 GVTVMSGSDIFVEFSRQRGLSADGRCKAFGPDADGTGWAEGVGTVVLERLSDARRLGHEV 2734 Query: 358 LAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRI 417 L V+ G+AVNQDG SNG+ AP+ RAQ V+ A A P+++D VEAHGTGT +GD I Sbjct: 2735 LGVVRGTAVNQDGASNGLSAPSGRAQQRVIRQALADAGCAPSDVDAVEAHGTGTRLGDPI 2794 Query: 418 EAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEV 477 EA AL +G+ R A +PL +GSIK NIGH + AAG+AG++K + L+ GQL + Sbjct: 2795 EAQALLTTYGQDRPADRPLYLGSIKSNIGHAQAAAGLAGVLKMLFALRHGQLPKTLHAPR 2854 Query: 478 PNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH------XXXXXXXXXX 531 P P + ++E +A++ E + WPA V RPRRAGVS+FG GTNAH Sbjct: 2855 PTPEVDWSEGAVALLTEDRPWPA-VDRPRRAGVSAFGVSGTNAHVILEQAPPSAASDPAP 2913 Query: 532 XXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHR 591 V WV++AR+ +GA A RL E A DV SLVTTR+++ R Sbjct: 2914 TVRPPAVDSSVQPWVLTARSGEALGALADRLRE---AAPGAVPADVARSLVTTRTIWAER 2970 Query: 592 AVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGY 651 AV++ GRDE +GLA + G V G A G+ VFVFPGQGAQW GM L Sbjct: 2971 AVLLADGRDEYASGLAALATGEGDARVVRGTADTRGRVVFVFPGQGAQWAGMAARLWESS 3030 Query: 652 PXXXXXXXXXXXELDRHLARPLREVVWGAD-AELLNTTEFAQPALFAVEVALYRLLESWG 710 P L L EV+ AD A L+ + QPA +AV V+L L S G Sbjct: 3031 PEFARWMDRCDKALGDLTDWSLAEVIHQADGAPGLDRVDVLQPASWAVSVSLAALWRSCG 3090 Query: 711 MRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLM-QALPGGGVMYAV---QAGEQ 766 + P V+GHS GE++AA V+G +R RL+ + L G G M +V AG Sbjct: 3091 VEPAAVVGHSQGEIAAACVAGALSLEDGAMLVTLRSRLIREELSGHGGMMSVALSPAGTA 3150 Query: 767 ELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEP 826 + ++ VAA N S V++G A++ ++ A G R RR+ V +A HS +E Sbjct: 3151 DRIACWEGRICVAAHNSRRSTVVAGEPAALAELLAACEADGIRARRIPVDYASHSPQVER 3210 Query: 827 MLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSA 886 + + +A + + IP S VTG + A YW R++R+ V F + Sbjct: 3211 IERKLTELAAGIVSRSSEIPFHSTVTGTRLHTTGLDAGYWYRNLRKPVLFGPVTEELLTQ 3270 Query: 887 GATRFVEVGPAGGLTSLIEESLAQV--SVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXD 944 G F+E+ P L ++E+ V + AV +LR+ P D Sbjct: 3271 GHDVFLEMSPHPVLVPAVQEASDAVTATAAAVGSLRRGDGGPERFLLSLAEAFVRGAHVD 3330 Query: 945 WASVLAGCGGQRVGLPTYAFAHERFW 970 WA+VL G G + V LPTY F RFW Sbjct: 3331 WAAVLGGTGTRLVELPTYPFQRTRFW 3356 Score = 85.1 bits (209), Expect = 1e-13 Identities = 46/84 (54%), Positives = 54/84 (64%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GLS E+Q VL +V HTAAVLG A +D QAF G SL+AVELRN L+T Sbjct: 5979 RLAGLSAPERQRHVLDLVRRHTAAVLGHGSADDVDPDQAFKALGFDSLTAVELRNHLRTA 6038 Query: 1070 TGVTLSATTAFDYPTPTQLADHLL 1093 T + + AT FD+PTP LA HLL Sbjct: 6039 TSLAVPATLVFDHPTPAALAAHLL 6062 Score = 85.1 bits (209), Expect = 1e-13 Identities = 46/84 (54%), Positives = 54/84 (64%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GLS E+Q VL +V HTAAVLG A +D QAF G SL+AVELRN L+T Sbjct: 5979 RLAGLSAPERQRHVLDLVRRHTAAVLGHGSADDVDPDQAFKALGFDSLTAVELRNHLRTA 6038 Query: 2082 TGVTLSATTAFDYPTPTQLADHLL 2105 T + + AT FD+PTP LA HLL Sbjct: 6039 TSLAVPATLVFDHPTPAALAAHLL 6062 Score = 67.0 bits (162), Expect = 3e-08 Identities = 52/157 (33%), Positives = 69/157 (43%), Gaps = 14/157 (8%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L D E+ +L +V A LG G + + F + G SL+AV+LRNRL Sbjct: 3895 RLAQLPDGERDRELLDLVRNAAALALGHTGTEPITPSKPFKELGFDSLTAVDLRNRLTAA 3954 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 TG+ L AT FDYPTP AD L + L + T R DDD Sbjct: 3955 TGLRLPATLVFDYPTPRAAADALRAVLFAADMPVDTAAPAR---------SASARPADDD 4005 Query: 2142 GWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDV 2178 +VA+A TT P++ W L+A G + Sbjct: 4006 PVVVVAMACRYPGGATT--PEKFWD---LIAAGEDGI 4037 Score = 55.1 bits (131), Expect = 1e-04 Identities = 32/83 (38%), Positives = 43/83 (51%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL+ E + A+ MV AAVLG ++ + F G SL VE RNRL Sbjct: 2371 RLAGLAGDELRQALDDMVTVEVAAVLGFRAKDRVPTDRTFKSLGFDSLIGVEFRNRLAAA 2430 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 G L + +D+PTP +L +HL Sbjct: 2431 LGRRLPPSLIYDHPTPGRLVEHL 2453 >tr|O54666|O54666_AMYMD Tax_Id=33910 (rifA)SubName: Full=RifA; SubName: Full=Rifamycin polyketide synthase, type 1;[Amycolatopsis mediterranei] Length = 4735 Score = 1502 bits (3889), Expect = 0.0 Identities = 905/2001 (45%), Positives = 1176/2001 (58%), Gaps = 92/2001 (4%) Query: 8 ADALQEWFTHYIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAV 66 A AL + + A G AE V+ +D G S+ + + L+ G+ + + Sbjct: 2101 AAALLDLVRRHAAEVLGHSGAESVHSGRTFKDAGFDSLTAVELRNRLAAATGLTLSPAMI 2160 Query: 67 WDNP---SAHDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGV 123 +D P + D +++ L G + R A+ +G EPIA++ MACRF G VH Sbjct: 2161 FDYPKPPALADHLRAKLFGSAANRPAE-------IGTAAAEEPIAIVAMACRFPGGVHSP 2213 Query: 124 GPLWDFLAEKKSAITEYPARRLGAAAADWL----GDEQETIY---GCFLEDVEGFDNKFF 176 LW +A+ A+TE+PA R D L D + T Y G FL+D GFD FF Sbjct: 2214 EDLWRLVADGADAVTEFPADR--GWDTDRLYHEDPDHEGTTYVRHGAFLDDAAGFDAAFF 2271 Query: 177 DIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDY-VRLLFPGG 235 I P+EA MDPQQRLLLETSW E A I P TL GVF GV+S DY +R+ G Sbjct: 2272 GISPNEALAMDPQQRLLLETSWELFERAAIDPTTLAGQDIGVFAGVNSHDYSMRMHRAAG 2331 Query: 236 RKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAV 295 + + TGGS+S+++ R++Y V GP++ +DTACSSSLVA H+A ++L GEC +A+ Sbjct: 2332 VEG--FRLTGGSASVLSGRVAYHFGVEGPAVTVDTACSSSLVALHMAVQALQRGECSMAL 2389 Query: 296 VAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGR 355 G V+ + E + F ++P G C+AF ADG EG G++++ERLS+A+R G Sbjct: 2390 AGGVMVMGTVETFVEFSRQRGLAPDGRCKAFADGADGTGWSEGVGLLLVERLSEAQRRGH 2449 Query: 356 TVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGD 415 VLAV+ GSAVN DG SNG+ APN +Q V+ A A + +++D VEAHGTGT++GD Sbjct: 2450 QVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIRKALAAAGLSTSDVDAVEAHGTGTTLGD 2509 Query: 416 RIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF 475 IEA AL +G+ R+ PL +GS+K N+GH + AAG+AG+IK V+ ++ G L + Sbjct: 2510 PIEAEALLATYGQNRET--PLWLGSVKSNLGHTQAAAGVAGVIKMVMAMRHGVLPRTLHV 2567 Query: 476 EVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXX 535 + P+ + ++ + ++ E ++W + G PRRAGVSSFG GGTNAH Sbjct: 2568 DRPSSYVDWSAGAVELLTEARDWVSN-GHPRRAGVSSFGIGGTNAHVVLEEVAAPITTPQ 2626 Query: 536 XXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVV 595 ++ +VSARTAAG+ QAGRL F+ ++ D Y+L TTR+ +HRAVV+ Sbjct: 2627 PEPAEFLVPVLVSARTAAGLRGQAGRLAAFLGDRTDVRVPDAAYALATTRAQLDHRAVVL 2686 Query: 596 GAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXX 655 + R +L A LA G GV +G + G K +F GQG+QW GMGREL +P Sbjct: 2687 ASDRAQLCADLAAF-----GSGVVTGTPVDG-KLAVLFTGQGSQWAGMGRELAETFPVFR 2740 Query: 656 XXXXXXXXELDRHLA-RPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPG 714 +D HL RPLREVV+ D+ LL+ T + Q ALFAVE AL+RL ESWG+RPG Sbjct: 2741 DAFEAACEAVDTHLRERPLREVVFD-DSALLDQTMYTQGALFAVETALFRLFESWGVRPG 2799 Query: 715 LVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGE 774 L+ GHS+GEL+AAHVSG RGRLMQALP GG M AVQA E E+ PLL Sbjct: 2800 LLAGHSIGELAAAHVSGVLDLADAGELVAARGRLMQALPAGGAMVAVQATEDEVAPLLDG 2859 Query: 775 QVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAV 834 V VAAVNGP SVVLSG AV V D LA +GR+ RRLAVSHAFHS LMEPML+ FRAV Sbjct: 2860 TVCVAAVNGPDSVVLSGTEAAVLAVADELAGRGRKTRRLAVSHAFHSPLMEPMLDDFRAV 2919 Query: 835 ADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEV 894 A+ + ++PV+S +TG+L A D S DYWV +R AVRF+D+V + GA+ F+E+ Sbjct: 2920 AERLTYRAGSLPVVSTLTGELAALD--SPDYWVGQVRNAVRFSDAVTALGAQGASTFLEL 2977 Query: 895 GPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGG 954 GP G L ++ +L V TLRK+ E DW +VL Sbjct: 2978 GPGGALAAMALGTLGGPEQSCVATLRKNGAEVPDVLTALAELHVRGVGVDWTTVLDE-PA 3036 Query: 955 QRVG--LPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQ 1012 VG LPTYAF H+RFW+ + Sbjct: 3037 TAVGTVLPTYAFQHQRFWV-------------------------DVDETAAVSVTPPPAE 3071 Query: 1013 GLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGV 1072 + D Q VL +V E A VLG A D ++F D G SLSAV+LRNRL+ TGV Sbjct: 3072 PIVDRPVQD-VLELVRESAAVVLGHRDAGSFDLDRSFKDHGFDSLSAVKLRNRLRDFTGV 3130 Query: 1073 TLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVS 1132 L +T FDYP P LADHL + L + +APA TR DEPIAIVGM R PGG Sbjct: 3131 ELPSTLIFDYPNPAVLADHLRAELLGERPAAPAPV--TRDVSDEPIAIVGMSTRLPGGAD 3188 Query: 1133 SPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFF 1192 SP +LW+LVA G D + FP DRGWD++ L+ PDP G +YTR GGF+ D A FD G F Sbjct: 3189 SPEELWKLVAEGRDAVSGFPVDRGWDLDGLYHPDPAHAGTSYTRSGGFLHDAAQFDAGLF 3248 Query: 1193 GISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQA-- 1250 GISP EALAMDPQQRLLLETSWEALE AG+DP + RGS GVF GI Y + Sbjct: 3249 GISPREALAMDPQQRLLLETSWEALERAGVDPLSARGSDVGVFTGIVHHDYVTRLREVPE 3308 Query: 1251 --QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALA 1308 Q Y TG +SVASGR++Y G GPA++VDTACSSSLVA+HLAA +LR GEC +ALA Sbjct: 3309 DVQGYTMTGTASSVASGRVAYVFGFEGPAVTVDTACSSSLVAMHLAAQALRQGECSMALA 3368 Query: 1309 GGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQP 1368 GG+TV+A+P F+ FSRQRGL+ DGRCKA+A+ ADGTG++EG G++VL+RLS AR G Sbjct: 3369 GGATVMASPDAFLEFSRQRGLSADGRCKAYAEGADGTGWAEGVGVVVLERLSVARERGHR 3428 Query: 1369 VLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDP 1428 VLA+L GSAVNQDGASNGLTAP+GP+QQRVI AL+ AG+ +DVDVVE HGTGT LGDP Sbjct: 3429 VLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRGALASAGLAPSDVDVVEGHGTGTALGDP 3488 Query: 1429 IEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHID 1488 IE QALLATYG++ + PLWLGS+KSN+GH+QAAAGV GVIKM+ AMRH ++PATLH+D Sbjct: 3489 IEVQALLATYGQER--EQPLWLGSLKSNLGHTQAAAGVVGVIKMIMAMRHGVMPATLHVD 3546 Query: 1489 QPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXX 1548 + ++ VDWS G +++LTEAREWP GRPRRAGVSSFG SGTNAH Sbjct: 3547 ERTSQVDWSAGAIEVLTEAREWPR-TGRPRRAGVSSFGASGTNAHLIIEEGPAEEAVDEE 3605 Query: 1549 XXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVG 1608 V+ VVSAR+A + QAGRL + E AG G +LV+ R+ RAVV+ Sbjct: 3606 V--ASVVPLVVSARSAGSLAGQAGRLAAVLE--NESLAGVAG-ALVSGRATLNERAVVIA 3660 Query: 1609 AGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXX 1668 RDE GL + G GV +G A GK V+VFPGQG+QW+GMGR+L P Sbjct: 3661 GSRDEAQDGLQALARGENAPGVVTGTAGKPGKVVWVFPGQGSQWMGMGRDLLDSSPVFAA 3720 Query: 1669 XXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLV 1728 L++ L +V+ G DA+LL+ + QPA FA+ V L + S G+ P V Sbjct: 3721 RIKECAAALEQWTDWSLLDVLRG-DADLLDRVDVVQPASFAMMVGLAAVWTSLGVTPDAV 3779 Query: 1729 MGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA-LPGGGVMYAVQAGEQELRPLL--- 1784 +GHS GE++AA VSG +R + + L G G M +V E++ L Sbjct: 3780 LGHSQGEIAAACVSGALSLDDAAKVVALRSQAIAGELAGRGGMASVALSEEDAVARLTPW 3839 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V VAAVN P SVV++G +A+ ++ LA G RVRR+AV +A H+ +E + E Sbjct: 3840 ANRVEVAAVNSPSSVVIAGDAQALDEALEALAGDGVRVRRVAVDYASHTRHVEAIAETLA 3899 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 + A PAIP S V G + + A YW R++R+ VRF SV G T FV Sbjct: 3900 KTLAGIDARVPAIPFYSTVLGTWIEQAVVDAGYWYRNLRQQVRFGPSVADLAGLGHTVFV 3959 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPT--LRKDRPEPFXXXXXXXXXXXXXXXXDWASVLA 1962 E+ ++ + L+++S AV T LR+D DW + + Sbjct: 3960 EI----SAHPVLVQPLSEISDDAVVTGSLRRDDGGLRRLLASAAELYVRGVAVDWTAAVP 4015 Query: 1963 GCGGQRVGLPTYAFAHERFWL 1983 G V LPTYAF FWL Sbjct: 4016 AAGW--VDLPTYAFDRRHFWL 4034 Score = 1030 bits (2664), Expect = 0.0 Identities = 586/1164 (50%), Positives = 723/1164 (62%), Gaps = 49/1164 (4%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL++ EQ AA+L +V H A VLG GA + +G+ F DAG SL+AVELRNRL Sbjct: 2091 RLAGLAETEQAAALLDLVRRHAAEVLGHSGAESVHSGRTFKDAGFDSLTAVELRNRLAAA 2150 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TG+TLS FDYP P LADHL + L + PA +EPIAIV M CR+PG Sbjct: 2151 TGLTLSPAMIFDYPKPPALADHLRAKLFGSAANRPAEIGTAAA--EEPIAIVAMACRFPG 2208 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV SP LW+LVA G D + EFP DRGWD +RL+ DPD G TY RHG F+ D A FD Sbjct: 2209 GVHSPEDLWRLVADGADAVTEFPADRGWDTDRLYHEDPDHEGTTYVRHGAFLDDAAGFDA 2268 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ 1249 FFGISP EALAMDPQQRLLLETSWE E A IDP L G GVF G+ Y + + Sbjct: 2269 AFFGISPNEALAMDPQQRLLLETSWELFERAAIDPTTLAGQDIGVFAGVNSHDYSMRMHR 2328 Query: 1250 A---QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLA 1306 A + + TG SV SGR++Y G+ GPA++VDTACSSSLVALH+A +L+ GEC +A Sbjct: 2329 AAGVEGFRLTGGSASVLSGRVAYHFGVEGPAVTVDTACSSSLVALHMAVQALQRGECSMA 2388 Query: 1307 LAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAG 1366 LAGG V+ T F+ FSRQRGLA DGRCKAFAD ADGTG+SEG G+L+++RLS+A+R G Sbjct: 2389 LAGGVMVMGTVETFVEFSRQRGLAPDGRCKAFADGADGTGWSEGVGLLLVERLSEAQRRG 2448 Query: 1367 QPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLG 1426 VLA++ GSAVN DGASNGLTAP+GP+QQRVI AL+ AG++ +DVD VEAHGTGT LG Sbjct: 2449 HQVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIRKALAAAGLSTSDVDAVEAHGTGTTLG 2508 Query: 1427 DPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLH 1486 DPIEA+ALLATYG++ + PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP TLH Sbjct: 2509 DPIEAEALLATYGQNR--ETPLWLGSVKSNLGHTQAAAGVAGVIKMVMAMRHGVLPRTLH 2566 Query: 1487 IDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXX 1546 +D+PS++VDWS G V+LLTEAR+W + G PRRAGVSSFG+ GTNAH Sbjct: 2567 VDRPSSYVDWSAGAVELLTEARDWVS-NGHPRRAGVSSFGIGGTNAHVVLEEVAAPITTP 2625 Query: 1547 XXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVV 1606 ++ +VSARTAAG+ QAGRL F+ ++ D Y+L TTR+ +HRAVV Sbjct: 2626 QPEPAEFLVPVLVSARTAAGLRGQAGRLAAFLGDRTDVRVPDAAYALATTRAQLDHRAVV 2685 Query: 1607 VGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXX 1666 + + R +L A LA G GV +G + GK +F GQG+QW GMGREL +P Sbjct: 2686 LASDRAQLCADLAAF-----GSGVVTGTPV-DGKLAVLFTGQGSQWAGMGRELAETFPVF 2739 Query: 1667 XXXXXXXXXELDRHL-ARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRP 1725 +D HL RPLREVV+ D+ LL+ T + Q ALFAVE AL+RL ESWG+RP Sbjct: 2740 RDAFEAACEAVDTHLRERPLREVVFD-DSALLDQTMYTQGALFAVETALFRLFESWGVRP 2798 Query: 1726 GLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLG 1785 GL+ GHS+GEL+AAHVSG RGRLMQALP GG M AVQA E E+ PLL Sbjct: 2799 GLLAGHSIGELAAAHVSGVLDLADAGELVAARGRLMQALPAGGAMVAVQATEDEVAPLLD 2858 Query: 1786 EQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRA 1845 V VAAVNGP SVVLSG AV V D LA +GR+ RRLAVSHAFHS LMEPML+ FRA Sbjct: 2859 GTVCVAAVNGPDSVVLSGTEAAVLAVADELAGRGRKTRRLAVSHAFHSPLMEPMLDDFRA 2918 Query: 1846 VADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVE 1905 VA+ + ++PV+S +TG+L A D S DYWV +R AVRF+D+V + GA+ F+E Sbjct: 2919 VAERLTYRAGSLPVVSTLTGELAALD--SPDYWVGQVRNAVRFSDAVTALGAQGASTFLE 2976 Query: 1906 VGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCG 1965 +GP G L ++ +L V TLRK+ E DW +VL Sbjct: 2977 LGPGGALAAMALGTLGGPEQSCVATLRKNGAEVPDVLTALAELHVRGVGVDWTTVLDE-P 3035 Query: 1966 GQRVG--LPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRL 2023 VG LPTYAF H+RFW+ Sbjct: 3036 ATAVGTVLPTYAFQHQRFWV-------------------------DVDETAAVSVTPPPA 3070 Query: 2024 QGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTG 2083 + + D Q VL +V E A VLG A D ++F D G SLSAV+LRNRL+ TG Sbjct: 3071 EPIVDRPVQ-DVLELVRESAAVVLGHRDAGSFDLDRSFKDHGFDSLSAVKLRNRLRDFTG 3129 Query: 2084 VTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRV--DALTDLFLQTCDAGRDDD 2141 V L +T FDYP P LADHL + L + P P V + + + + T G D Sbjct: 3130 VELPSTLIFDYPNPAVLADHLRAELLGERPAAPAPVTRDVSDEPIAIVGMSTRLPGGADS 3189 Query: 2142 GWQIVALAANGRERMTTPVPKREW 2165 ++ L A GR+ ++ R W Sbjct: 3190 PEELWKLVAEGRDAVSGFPVDRGW 3213 Score = 808 bits (2086), Expect = 0.0 Identities = 474/979 (48%), Positives = 603/979 (61%), Gaps = 36/979 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL + Q + +V A VLG+ + G+AF D G TSL+ VELRNRL Sbjct: 532 RLSGLDERAQCELLEDLVRTQAADVLGQP----VPDGRAFRDLGFTSLAIVELRNRLTEH 587 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TG+ L A+ FD+PTP LA + + L ++ V EPIAIVGM CR PG Sbjct: 588 TGLWLPASAVFDHPTPAALAARVRAELLGITQAVAEPVVAADP--GEPIAIVGMACRLPG 645 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV+SP LW+LVA D + EFP DRGWD++ L DPD + G +Y GGF+ D +FD Sbjct: 646 GVASPEDLWRLVAERVDAVSEFPGDRGWDLDSLIDPDRERAGTSYVGQGGFLHDAGEFDA 705 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGT-- 1247 GFFGISP EA+AMDPQQRLLLETSWEALE+AG+DP AL+G+ TGVF G+ G GYG G Sbjct: 706 GFFGISPREAVAMDPQQRLLLETSWEALENAGVDPIALKGTDTGVFSGLMGQGYGSGAVA 765 Query: 1248 SQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLAL 1307 + + + TG +SVASGR+SY LGL GPA++VDTACSSSLVA+HLAA +LR GEC +AL Sbjct: 766 PELEGFVTTGVASSVASGRVSYVLGLEGPAVTVDTACSSSLVAMHLAAQALRQGECSMAL 825 Query: 1308 AGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQ 1367 AGG TV+ATP F+ FSRQR LA DGRCKAFA AADGTG+SEG G++VL+RLS AR G Sbjct: 826 AGGVTVMATPGSFVEFSRQRALAPDGRCKAFAAAADGTGWSEGVGVVVLERLSVARERGH 885 Query: 1368 PVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGD 1427 +LA+L GSAVNQDGASNGLTAP+G +QQRVI AL+ AG+ +DVDVVEAHGTGT LGD Sbjct: 886 RILAVLRGSAVNQDGASNGLTAPNGLSQQRVIRRALAAAGLAPSDVDVVEAHGTGTTLGD 945 Query: 1428 PIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHI 1487 PIEAQALLATYG++ PLWLGS+KSN+GH+QAAAGVAGVIKMV+A+RH+ LP TLH+ Sbjct: 946 PIEAQALLATYGQER--KQPLWLGSLKSNIGHAQAAAGVAGVIKMVQALRHETLPPTLHV 1003 Query: 1488 DQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXX 1547 D+P+ VDWS G ++LLTEAR WP GRPRRAGVSSFGVSGTNAH Sbjct: 1004 DKPTLEVDWSAGAIELLTEARAWPR-NGRPRRAGVSSFGVSGTNAHLILEEAPAEEPVAA 1062 Query: 1548 XXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVV 1607 V+ VVSAR+ + QA RL + ++ +V +LV+ R++ + RAVVV Sbjct: 1063 PEL--PVVPLVVSARSTESLSGQAERLASLLEG--DVSLTEVAGALVSRRAVLDERAVVV 1118 Query: 1608 GAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXX 1667 R+E + GL + G GK V+VFPGQG QW GMGREL A P Sbjct: 1119 AGSREEAVTGLRALNTAGSGT---------PGKVVWVFPGQGTQWAGMGRELLAESPVFA 1169 Query: 1668 XXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGL 1727 L + L +V+ G L + QPA FAV V L + ES G+RP Sbjct: 1170 ERIAECAAALAPWIDWSLVDVLRGEGD--LGRVDVLQPACFAVMVGLAAVWESVGVRPDA 1227 Query: 1728 VMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA-LPGGGVMYAVQAGEQELRPLLGE 1786 V+GHS GE++AA VSG +R + + A L G G M +V GE ++ L + Sbjct: 1228 VVGHSQGEIAAACVSGALSLEDAAKVVALRSQAIAAELSGRGGMASVALGEDDVVSRLVD 1287 Query: 1787 QVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAV 1846 V VAAVNGP SVV++G A+ ++ L+ +G RVRR+AV +A H+ +E + + Sbjct: 1288 GVEVAAVNGPSSVVIAGDAHALDATLEILSGEGIRVRRVAVDYASHTRHVEDIRDTLAET 1347 Query: 1847 ADEVYAGRPAIPVISNVTGQLVAEDYGSAD--YWVRHIREAVRFADSVCFAHSAGATRFV 1904 + A PA+P S VT + V D G D YW R++R VRF + G T FV Sbjct: 1348 LAGISAQAPAVPFYSTVTSEWV-RDAGVLDGGYWYRNLRNQVRFGAAATALLEQGHTVFV 1406 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EV + + L++++ A+ TLR++ DW +++ Sbjct: 1407 EV----SAHPVTVQPLSELTGDAIGTLRREDGGLRRLLASMGELFVRGIDVDWTAMVPAA 1462 Query: 1965 GGQRVGLPTYAFAHERFWL 1983 G V LPTYAF H +WL Sbjct: 1463 GW--VDLPTYAFEHRHYWL 1479 Score = 541 bits (1395), Expect = e-151 Identities = 369/950 (38%), Positives = 511/950 (53%), Gaps = 53/950 (5%) Query: 37 RDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPS----AHDVIKSVLGGDGSQRSADSD 92 RDLG S+ ++ + L++ G+ +P AV+D+P+ A V +LG +Q A+ Sbjct: 568 RDLGFTSLAIVELRNRLTEHTGLWLPASAVFDHPTPAALAARVRAELLGI--TQAVAEP- 624 Query: 93 TGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADW 152 V+ P EPIA++GMACR G V LW +AE+ A++E+P R G Sbjct: 625 ----VVAADP-GEPIAIVGMACRLPGGVASPEDLWRLVAERVDAVSEFPGDR-GWDLDSL 678 Query: 153 LGDEQE---TIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGI 206 + ++E T Y G FL D FD FF I P EA MDPQQRLLLETSW ALE+AG+ Sbjct: 679 IDPDRERAGTSYVGQGGFLHDAGEFDAGFFGISPREAVAMDPQQRLLLETSWEALENAGV 738 Query: 207 LPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTI--WDNTGGSSSIIANRLSYFLDVNGP 264 P LK + TGVF G+ Y G P + + TG +SS+ + R+SY L + GP Sbjct: 739 DPIALKGTDTGVFSGLMGQGYGS----GAVAPELEGFVTTGVASSVASGRVSYVLGLEGP 794 Query: 265 SLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCR 324 ++ +DTACSSSLVA HLA ++L GEC +A+ G V+ +P + F ++P G C+ Sbjct: 795 AVTVDTACSSSLVAMHLAAQALRQGECSMALAGGVTVMATPGSFVEFSRQRALAPDGRCK 854 Query: 325 AFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQI 384 AF A ADG EG GVVVLERLS AR G +LAVL GSAVNQDG SNG+ APN +Q Sbjct: 855 AFAAAADGTGWSEGVGVVVLERLSVARERGHRILAVLRGSAVNQDGASNGLTAPNGLSQQ 914 Query: 385 SVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPN 444 V+ A A + P+++D VEAHGTGT++GD IEA AL +G+ R+ +PL +GS+K N Sbjct: 915 RVIRRALAAAGLAPSDVDVVEAHGTGTTLGDPIEAQALLATYGQERK--QPLWLGSLKSN 972 Query: 445 IGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGR 504 IGH + AAG+AG+IK V L+ L P+ + P + ++ + ++ E + WP GR Sbjct: 973 IGHAQAAAGVAGVIKMVQALRHETLPPTLHVDKPTLEVDWSAGAIELLTEARAWPR-NGR 1031 Query: 505 PRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLE 564 PRRAGVSSFG GTNAH V+ VVSAR+ + QA RL Sbjct: 1032 PRRAGVSSFGVSGTNAHLILEEAPAEEPVAAPEL--PVVPLVVSARSTESLSGQAERLAS 1089 Query: 565 FVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAM 624 + ++ +V +LV+ R++ + RAVVV R+E + GL + G Sbjct: 1090 LLEG--DVSLTEVAGALVSRRAVLDERAVVVAGSREEAVTGLRALNTAGSGT-------- 1139 Query: 625 PGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAEL 684 GK V+VFPGQG QW GMGREL A P L + L +V+ G Sbjct: 1140 -PGKVVWVFPGQGTQWAGMGRELLAESPVFAERIAECAAALAPWIDWSLVDVLRGEGD-- 1196 Query: 685 LNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXM 744 L + QPA FAV V L + ES G+RP V+GHS GE++AA VSG + Sbjct: 1197 LGRVDVLQPACFAVMVGLAAVWESVGVRPDAVVGHSQGEIAAACVSGALSLEDAAKVVAL 1256 Query: 745 RGRLMQA-LPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRL 803 R + + A L G G M +V GE ++ L + V VAAVNGP SVV++G A+ ++ L Sbjct: 1257 RSQAIAAELSGRGGMASVALGEDDVVSRLVDGVEVAAVNGPSSVVIAGDAHALDATLEIL 1316 Query: 804 AAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSA 863 + +G RVRR+AV +A H+ +E + + + A PA+P S VT + V D G Sbjct: 1317 SGEGIRVRRVAVDYASHTRHVEDIRDTLAETLAGISAQAPAVPFYSTVTSEWV-RDAGVL 1375 Query: 864 D--YWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRK 921 D YW R++R VRF + G T FVEV + + L++++ A+ TLR+ Sbjct: 1376 DGGYWYRNLRNQVRFGAAATALLEQGHTVFVEV----SAHPVTVQPLSELTGDAIGTLRR 1431 Query: 922 DRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 + DW +++ G V LPTYAF H +WL Sbjct: 1432 EDGGLRRLLASMGELFVRGIDVDWTAMVPAAGW--VDLPTYAFEHRHYWL 1479 Score = 73.2 bits (178), Expect = 4e-10 Identities = 40/93 (43%), Positives = 51/93 (54%) Query: 2023 LQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLT 2082 L+ + DAEQ +L +V H + VLG GA + QAF + G SL+AV LRN L T Sbjct: 4568 LRAVPDAEQNRILLKLVRGHASTVLGHSGAEGIGPRQAFQEVGFDSLAAVNLRNSLHAAT 4627 Query: 2083 GVTLSATTAFDYPTPTQLADHLLSHLHHQNPTG 2115 G+ L AT FDYPTP L +L L + G Sbjct: 4628 GLRLPATLIFDYPTPEALVGYLRVELLREADDG 4660 Score = 72.8 bits (177), Expect = 6e-10 Identities = 38/82 (46%), Positives = 48/82 (58%) Query: 1011 LQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLT 1070 L+ + DAEQ +L +V H + VLG GA + QAF + G SL+AV LRN L T Sbjct: 4568 LRAVPDAEQNRILLKLVRGHASTVLGHSGAEGIGPRQAFQEVGFDSLAAVNLRNSLHAAT 4627 Query: 1071 GVTLSATTAFDYPTPTQLADHL 1092 G+ L AT FDYPTP L +L Sbjct: 4628 GLRLPATLIFDYPTPEALVGYL 4649 Score = 60.1 bits (144), Expect = 4e-06 Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 4/87 (4%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL + Q + +V A VLG+ + G+AF D G TSL+ VELRNRL Sbjct: 532 RLSGLDERAQCELLEDLVRTQAADVLGQP----VPDGRAFRDLGFTSLAIVELRNRLTEH 587 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L A+ FD+PTP LA + + L Sbjct: 588 TGLWLPASAVFDHPTPAALAARVRAEL 614 >tr|A0FCL1|A0FCL1_STRVO Tax_Id=68280 (merA)SubName: Full=MerA;[Streptomyces violaceoniger] Length = 5721 Score = 1442 bits (3733), Expect = 0.0 Identities = 875/1949 (44%), Positives = 1093/1949 (56%), Gaps = 91/1949 (4%) Query: 100 NGPTNEP-----------IAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRL--- 145 NGP ++P IAV+GM+CRF Q W L E SAI+E PA R Sbjct: 8 NGPADDPAPRKRMEPDEAIAVVGMSCRFP-QAPDPEAFWRLLNEGISAISEVPAGRWIDD 66 Query: 146 --------------------GAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAAL 185 + AAD +G F++DV+ FD FF I P EA Sbjct: 67 RPAPPGTDAPSTPPGTDDPSTSLAADASSTPPAVRHGGFIDDVDRFDPAFFGISPREAVA 126 Query: 186 MDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTG 245 MDPQQRL+LE +W LE AGI+P TL+ + G F+G S DY L+ GR TG Sbjct: 127 MDPQQRLILELAWEGLEDAGIVPATLRGATVGAFIGAGSDDYGSLIRARGRSHHTL--TG 184 Query: 246 GSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISP 305 ++ANRLS+ ++GPSL +D A +SSLVA H+A +SL GE LA+ G N+ +S Sbjct: 185 TQRGMLANRLSHVFGLSGPSLTVDAAQASSLVAVHMAVESLRRGESRLALAGGVNLNLSA 244 Query: 306 EVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSA 365 E G +SP G C FDARA+G VRGEG G+VVL+ LSDA G TV V+ GSA Sbjct: 245 ETAADIAAFGALSPDGRCFTFDARANGYVRGEGGGLVVLKPLSDALADGDTVYCVIEGSA 304 Query: 366 VNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQV 425 VN DG + AP+P Q VL A + A I PA + YVE HGTGT++GD EA ALG V Sbjct: 305 VNNDGGGVSLTAPDPDGQRQVLRLAQRRAGISPAAVQYVELHGTGTALGDPAEAEALGAV 364 Query: 426 FGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFA 485 FGR P+ +GS+K NIGHLE AAGIAGL+KT L + QL + PNP IP Sbjct: 365 FGRS--GGGPVQLGSVKTNIGHLEAAAGIAGLLKTALAIHHRQLPAGLNYRTPNPRIPMG 422 Query: 486 ELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGV--- 542 EL L + EWP R AGVSSFG GGTN H P Sbjct: 423 ELNLEMRLAPGEWPKPDNR-LVAGVSSFGMGGTNCHVVLAEPPAWASSHASAHHPEPEAV 481 Query: 543 ---------LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAV 593 L +S +AA + QA RL ++ L D+ +SL TTR+ F+HRAV Sbjct: 482 PAPTLAPIPLPLPLSGVSAAALRGQAMRLRPYLERSPNLT--DLAFSLATTRTSFDHRAV 539 Query: 594 VVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPX 653 ++ + GL + EG G+ G A GK F F GQG+Q LGMG EL A +P Sbjct: 540 LISGQATDAAHGLDALAEGGAAAGLVMGTARAAGKLAFAFAGQGSQRLGMGGELSAAFPV 599 Query: 654 XXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRP 713 LD HL RPLR+V+ G DAELL+ T +AQ LFAVEVAL+RLLE +G+ P Sbjct: 600 FAQALDEVCTALDAHLDRPLRDVIHGDDAELLDRTVYAQAGLFAVEVALFRLLEDFGLVP 659 Query: 714 GLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL- 772 L++GHS+GE+SAAHV+G RGRLMQA+ G M +++A E E+ L Sbjct: 660 DLLIGHSLGEVSAAHVAGVLSLADAAAFVAARGRLMQAVTEPGAMVSLEATEDEVTRTLM 719 Query: 773 -------GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLME 825 G +V VAAVNGP + V+SG AV + +GRR +RL SHAFHS ++ Sbjct: 720 AGGASDDGVRVCVAAVNGPTATVISGDERAVLDLAAEWTRRGRRTKRLRTSHAFHSPHLD 779 Query: 826 PMLEQFRAVADEVYAGRPAIPVISNVTGQ-LVAEDYGSADYWVRHIREAVRFADSVCFAH 884 P+L++ R +A+ + P IP++SNVTG+ AE+ S +YWVRH+R VRF D V Sbjct: 780 PVLDELRHIAESLTYQAPRIPLVSNVTGRRATAEELCSPEYWVRHVRRTVRFLDGVRCLE 839 Query: 885 SAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXD 944 G T VE+GP L++L + L + V TLR+DRPEP Sbjct: 840 GEGVTTIVELGPDKALSTLARDCLTGPGTL-VGTLRRDRPEPQALVTALAELYASGVEVA 898 Query: 945 WASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXX 1004 W +++G G+R+ LPTYAF +R+W + + Sbjct: 899 WDPLVSG--GRRIPLPTYAFQRQRYWFSAP-GAEGGDTSAHGVTSGPERTDTGLSPDEAL 955 Query: 1005 XXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRN 1064 + L VL MV H A VLG + A + A F G S++AVEL Sbjct: 956 DEGPSNSKVLDTGLSGGEVLGMVRAHAAVVLGYETANAIGAEHTFKQLGFDSITAVELCE 1015 Query: 1065 RLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMG 1124 RL T + L T FDYPTPT LA+HL LH + A +P+ IVGMG Sbjct: 1016 RLGEATALPLPGTLLFDYPTPTALAEHLHRRLHGRTDEQAVPATVPTPAGGDPVVIVGMG 1075 Query: 1125 CRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDV 1184 CR+PG SP LW++V G D I FP DRGWD++ L+ PDPD G +Y R GGF+ D Sbjct: 1076 CRFPGRAHSPEDLWRIVVDGEDAISGFPSDRGWDLDGLYHPDPDRSGTSYARDGGFLYDA 1135 Query: 1185 ADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG 1244 A+FD GFFGISP EA AMDPQQRLLLETSWEALE AGI + ++GSSTGVF+G GY Sbjct: 1136 AEFDAGFFGISPREAAAMDPQQRLLLETSWEALERAGIPAEHIKGSSTGVFIGASSVGYA 1195 Query: 1245 LGTSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGEC 1303 + A+ Y TG SVASGR+SY LGL GPA++VDTACSSSLVALHLA SLRAGEC Sbjct: 1196 ADAGEEAEGYQLTGTAASVASGRVSYTLGLEGPAVTVDTACSSSLVALHLAVQSLRAGEC 1255 Query: 1304 DLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDAR 1363 LALAGG TV+ATP++F+ FSRQRGLATDGRCKAFA AADGTG++EG G+LV++RLSDA Sbjct: 1256 SLALAGGVTVMATPAMFVEFSRQRGLATDGRCKAFAAAADGTGWAEGVGVLVVERLSDAE 1315 Query: 1364 RAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGT 1423 R G VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AL AG+ +DVD VEAHG GT Sbjct: 1316 RNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALVSAGLVASDVDAVEAHGYGT 1375 Query: 1424 RLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPA 1483 LGDPIEAQALLATYG+D D PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP Sbjct: 1376 TLGDPIEAQALLATYGQDRDADRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPQ 1435 Query: 1484 TLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH----XXXXXX 1539 TLH+D+ S HVDWS G V+LLTEA WP V RRAGVSSFGVSGTNAH Sbjct: 1436 TLHVDEWSPHVDWSGGRVELLTEATPWPMTV---RRAGVSSFGVSGTNAHIILEQAPETA 1492 Query: 1540 XXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 1599 +AWV+S + AG+ AQA RL F A +VG+SL +TR+ Sbjct: 1493 QPTRPIPEGDTEVAAVAWVLSGQGEAGLRAQAERLRAFTAASPCPTPAEVGWSLASTRTT 1552 Query: 1600 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 1659 HRAVVVGAGRDELL G+ V G GV G P G VFVFPGQG+QW+GM EL Sbjct: 1553 LSHRAVVVGAGRDELLRGVDAVANGMAAPGVVRGTGAP-GDVVFVFPGQGSQWVGMALEL 1611 Query: 1660 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 1719 L + L +V+ D L+ + QP L+AV V+L L Sbjct: 1612 VESSSVFAGRLGECAEALGPLVEWSLWDVL--GDEVALSRVDVVQPVLWAVMVSLAELWR 1669 Query: 1720 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 1779 S+G+ P V+GHS GE++AA V+G +R R + AL G G M +V Sbjct: 1670 SFGVVPSAVVGHSQGEIAAACVAGGLSLEDGARVVALRSRALLALSGRGGMVSVPVSADR 1729 Query: 1780 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 1839 LR G +SVAAVNGP S V+SG EA+ V++ +R+ V +A HSV +E + Sbjct: 1730 LRDRAG--LSVAAVNGPVSTVVSGPVEALDAVLEEFP----EAKRIPVDYASHSVQVEEI 1783 Query: 1840 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 1899 E V +P S VTG+L+ A+YW R++RE V F +V G Sbjct: 1784 REGLAEALASVRPRTGEVPFYSTVTGRLMDTSELDAEYWYRNLRETVEFQSTVEHLMREG 1843 Query: 1900 ATRFVEVGPAGGLTSLIEES-----LAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXX 1954 T FVE P LT I+++ ++ +LR+D Sbjct: 1844 HTVFVEASPHPVLTVGIQDTADATDTTHTDILVTGSLRRDDGTVQRFLTSLAELHVRGVR 1903 Query: 1955 XDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DW + AG V LPTYAF ERFWL Sbjct: 1904 IDWGPLFAGV--SPVELPTYAFQRERFWL 1930 Score = 959 bits (2480), Expect = 0.0 Identities = 535/986 (54%), Positives = 642/986 (65%), Gaps = 39/986 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 +L G+++AE+Q +L +V EH A VLG A +DA + F + G SL+AVELRNR+ Sbjct: 4094 QLAGVTEAERQNRILRLVREHVAGVLGHASAESVDASRTFQEIGFDSLTAVELRNRISAA 4153 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRI--DEPIAIVGMGCRY 1127 GV L AT FD+PTP LA+ +L+ + S P AA V DEPI IVGM CR+ Sbjct: 4154 IGVRLPATAVFDHPTPRLLAERVLAEVWG---SLPTAAPIMPVSAVDDEPIVIVGMSCRF 4210 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGGV SP LW LV S D + P DRGWD+ L A G +Y + GGF+ D A+F Sbjct: 4211 PGGVGSPEDLWHLVNSATDAVSALPTDRGWDLATLSGGKGGA-GASYAQDGGFLYDAAEF 4269 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGT 1247 D GFFGISP EA AMDPQQRLLLET+WE E AGI P L+GS TGVF G+ YG Sbjct: 4270 DAGFFGISPREATAMDPQQRLLLETAWEVFERAGIAPDTLKGSRTGVFTGVMYHDYGSWL 4329 Query: 1248 SQA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGEC 1303 + + Y TG SVASGR++Y GL GPA++VDTACSSSLVALHLAA SLR GEC Sbjct: 4330 TDVPDDVEGYLGTGIAGSVASGRLAYTFGLEGPALTVDTACSSSLVALHLAAESLRRGEC 4389 Query: 1304 DLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDAR 1363 LALAGG TVLATP +F+ F+RQ GLA DGRCK+FA ADGTG+SEG G+L+++RLSDA Sbjct: 4390 SLALAGGVTVLATPQVFVEFTRQGGLAPDGRCKSFAAGADGTGWSEGVGLLLVERLSDAE 4449 Query: 1364 RAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGT 1423 R G VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+ AG+ DVD VEAHGTGT Sbjct: 4450 RNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIQQALASAGLAARDVDAVEAHGTGT 4509 Query: 1424 RLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPA 1483 LGDPIEAQALLATYG+D P PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP Sbjct: 4510 TLGDPIEAQALLATYGQDRDPGRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPR 4569 Query: 1484 TLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXX 1543 TLH+D+PS HVDWS G V+LL E WP GRPRRAGVSSFG SGTNAH Sbjct: 4570 TLHVDEPSPHVDWSAGAVELLGEHTAWPE-AGRPRRAGVSSFGASGTNAH--VILEQAPD 4626 Query: 1544 XXXXXXXGPG-----VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRS 1598 GP + WV SA+ AGV AQA RL F +LD DVG+SL TR+ Sbjct: 4627 TASEPEPGPARSELPAIPWVFSAQDEAGVRAQAVRLRAFADRNADLDPVDVGWSLAATRA 4686 Query: 1599 LFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRE 1658 HRAVVVGA R+ELL L EG P V GV + GG V +F GQG+Q LGMGR Sbjct: 4687 GLSHRAVVVGADREELLGAL----EGAPVV----GVPVVGGLGV-LFAGQGSQRLGMGRG 4737 Query: 1659 LCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLL 1718 L YP ELDR++ R + EVVWG DAEL+ T +AQ LFA+EVALYRL+ Sbjct: 4738 LYEAYPVFAVAWDEVCAELDRYVDRSVGEVVWGDDAELIGETVYAQAGLFALEVALYRLI 4797 Query: 1719 ESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQ 1778 SWG++P ++GHS+GEL+AA+V+G RGRLMQ LP GGVM AV A E Sbjct: 4798 ASWGVKPDYLLGHSIGELAAAYVAGVWSLEDAARVVAARGRLMQGLPSGGVMVAVAASEG 4857 Query: 1779 ELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEP 1838 E+ PLL + VSVAAVN P SVV+SG +AV V D L +G R RR+ VSHAFHS M+ Sbjct: 4858 EVLPLLADAVSVAAVNAPESVVVSGDEDAVRAVADVL--RGVRTRRVRVSHAFHSARMDG 4915 Query: 1839 MLEQF-RAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHS 1897 ML +F + V P++PV+SNVTG++ E+ S +YWVRH+RE VRFAD + Sbjct: 4916 MLAEFGEVLLAGVEFHAPSLPVVSNVTGEVAGEELCSPEYWVRHVRETVRFADGLDTLRE 4975 Query: 1898 AGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDW 1957 G F+E+GP G L +L + +P LR+DRPEP DW Sbjct: 4976 LGVGSFLELGPDGTLAALTDGD-------GLPVLRRDRPEPLSLMAALGGLYVRGVGVDW 5028 Query: 1958 ASVLAGCGGQRVGLPTYAFAHERFWL 1983 +V GG+RV LPTYAF +RFWL Sbjct: 5029 GAVFP--GGRRVDLPTYAFQRQRFWL 5052 Score = 815 bits (2105), Expect = 0.0 Identities = 478/986 (48%), Positives = 592/986 (60%), Gaps = 32/986 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL +S A+Q ++ +V EH A +LG G A +D F G SL+AVELR RL Sbjct: 2419 RLAEVSTADQDRTLVDLVREHAAELLGHHGPAAIDPTVPFRRLGFDSLTAVELRTRLNAA 2478 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNR------SAPAAAVRTRVRIDEPIAIVGM 1123 TG+ L AT FD+P+ +AD L S L SA AA V DEPIAIV M Sbjct: 2479 TGLRLPATLLFDHPSCRAVADLLRSELLGGRSGPLAVPSATEAAPVGAVASDEPIAIVAM 2538 Query: 1124 GCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSD 1183 CR+PGG+ SP LW++V+ G +V+ +FP DRGWD+E L+DPDPD +Y R G F+ D Sbjct: 2539 SCRFPGGIESPEDLWRVVSEGREVLSDFPDDRGWDVEALYDPDPDRPRTSYVRTGAFLHD 2598 Query: 1184 VADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGY 1243 A+FDP FGISP EALAMDPQQRLLLE++W+ LE A + ++R S TGVF+G +G GY Sbjct: 2599 AAEFDPELFGISPREALAMDPQQRLLLESAWQVLERARMASTSMRSSRTGVFIGGWGQGY 2658 Query: 1244 GLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGEC 1303 + + YA TG TSV SGRI+Y LGL GPA++VDTACSSSLVALHLA+ +LR GEC Sbjct: 2659 PSASDEG--YALTGAATSVMSGRIAYALGLEGPALTVDTACSSSLVALHLASEALRRGEC 2716 Query: 1304 DLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDAR 1363 LALAGG TV+ATPS F+ FSRQRGLA DGRCKAFA AADGTG+ EG GML+L+RLSDA Sbjct: 2717 SLALAGGVTVMATPSTFVEFSRQRGLAPDGRCKAFAGAADGTGWGEGVGMLLLERLSDAE 2776 Query: 1364 RAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGT 1423 R G VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AL++A ++ DVDVVEAHGTGT Sbjct: 2777 RNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLSTVDVDVVEAHGTGT 2836 Query: 1424 RLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPA 1483 LGDPIEAQALLATYG+D D PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP Sbjct: 2837 TLGDPIEAQALLATYGQDRDADRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPR 2896 Query: 1484 TLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXX 1543 TLH+D+P+ VDW+ G V+LLTE EWP GRPRRAGVS+FGVSGTNAH Sbjct: 2897 TLHVDEPTPKVDWTTGAVELLTEPAEWPQ-EGRPRRAGVSAFGVSGTNAHVILEQAPEVA 2955 Query: 1544 XXXXXXXG-PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEH 1602 P + WV+S A + Q RL FV LD DVG+SL +TR+L + Sbjct: 2956 AERRQGRDEPVAVPWVLSGANEAALRGQIERLRAFVDDNPTLDPVDVGWSLTSTRALLPY 3015 Query: 1603 RAVVVGAGRDELLAGL--AEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELC 1660 R VVVGA EL GL AEVV G A P V VFPGQG+QW+GM EL Sbjct: 3016 RTVVVGADLAELRHGLDTAEVV----------GAAEPDRGAVLVFPGQGSQWVGMALELV 3065 Query: 1661 AGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLES 1720 L + L +V+ D L+ + QP L+AV V+L L S Sbjct: 3066 ESSSVFAGRLGECAAALGPLVEWSLWDVL--GDEVALSRVDVVQPVLWAVMVSLAELWRS 3123 Query: 1721 WGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQEL 1780 +G+ P V+GHS GE++AA V+G +R R + AL G G M +V L Sbjct: 3124 FGVVPSAVVGHSQGEIAAACVAGALSLEDGARVVALRSRALLALSGRGGMVSVPVSADRL 3183 Query: 1781 RPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPML 1840 R G +SVAAVNGP S V+SG EA+ V++ +R+ V +A HSV +E + Sbjct: 3184 RGRAG--LSVAAVNGPVSTVVSGPVEALDAVLEEFP----EAKRIPVDYASHSVQVEEIR 3237 Query: 1841 EQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGA 1900 E V +P S VTG+L+ +YW R++RE V F +V G Sbjct: 3238 EGLAEALASVRPRTGEVPFYSTVTGRLMDTVELDGEYWYRNLRETVEFRSAVEGLLELGH 3297 Query: 1901 TRFVEVGPAGGLTSLIEES--LAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWA 1958 T FVE P LT I+++ ++ +LR+D +W Sbjct: 3298 TVFVEASPHPVLTVGIQDTADATDTDILVTGSLRRDDGGLTSFLTALARLHVRGVAVEWR 3357 Query: 1959 SVLAGCGGQRVGLPTYAFAHERFWLA 1984 G V LPTYAF RFW A Sbjct: 3358 DAFTGLDAHAVELPTYAFQRRRFWAA 3383 Score = 702 bits (1813), Expect = 0.0 Identities = 424/972 (43%), Positives = 558/972 (57%), Gaps = 51/972 (5%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVI 76 ++A G SAE V+ +++G S+ + + +S +G+ +P AV+D+P+ + Sbjct: 4114 HVAGVLGHASAESVDASRTFQEIGFDSLTAVELRNRISAAIGVRLPATAVFDHPTPRLLA 4173 Query: 77 KSVLGGDGSQRSADSDTGCAVLG-NGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKS 135 + VL ++ T ++ + +EPI ++GM+CRF G V LW + Sbjct: 4174 ERVL----AEVWGSLPTAAPIMPVSAVDDEPIVIVGMSCRFPGGVGSPEDLWHLVNSATD 4229 Query: 136 AITEYPARR----------LGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAAL 185 A++ P R G A A + D G FL D FD FF I P EA Sbjct: 4230 AVSALPTDRGWDLATLSGGKGGAGASYAQD------GGFLYDAAEFDAGFFGISPREATA 4283 Query: 186 MDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTG 245 MDPQQRLLLET+W E AGI P TLK S TGVF GV DY L + TG Sbjct: 4284 MDPQQRLLLETAWEVFERAGIAPDTLKGSRTGVFTGVMYHDYGSWLTDVPDDVEGYLGTG 4343 Query: 246 GSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISP 305 + S+ + RL+Y + GP+L +DTACSSSLVA HLA +SL GEC LA+ G VL +P Sbjct: 4344 IAGSVASGRLAYTFGLEGPALTVDTACSSSLVALHLAAESLRRGECSLALAGGVTVLATP 4403 Query: 306 EVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSA 365 +V+ F G ++P G C++F A ADG EG G++++ERLSDA R G VLAV+ GSA Sbjct: 4404 QVFVEFTRQGGLAPDGRCKSFAAGADGTGWSEGVGLLLVERLSDAERNGHRVLAVVRGSA 4463 Query: 366 VNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQV 425 VNQDG SNG+ APN +Q V+ A A + ++D VEAHGTGT++GD IEA AL Sbjct: 4464 VNQDGASNGLTAPNGPSQQRVIQQALASAGLAARDVDAVEAHGTGTTLGDPIEAQALLAT 4523 Query: 426 FGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFA 485 +G+ R +PL +GS+K NIGH + AAG+AG+IK V+ ++ G L + + P+P++ ++ Sbjct: 4524 YGQDRDPGRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSPHVDWS 4583 Query: 486 ELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPG---- 541 + ++ E WP GRPRRAGVSSFG GTNAH GP Sbjct: 4584 AGAVELLGEHTAWPE-AGRPRRAGVSSFGASGTNAH--VILEQAPDTASEPEPGPARSEL 4640 Query: 542 -VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRD 600 + WV SA+ AGV AQA RL F +LD DVG+SL TR+ HRAVVVGA R+ Sbjct: 4641 PAIPWVFSAQDEAGVRAQAVRLRAFADRNADLDPVDVGWSLAATRAGLSHRAVVVGADRE 4700 Query: 601 ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXX 660 ELL L EG P V GV + GG V +F GQG+Q LGMGR L YP Sbjct: 4701 ELLGAL----EGAPVV----GVPVVGGLGV-LFAGQGSQRLGMGRGLYEAYPVFAVAWDE 4751 Query: 661 XXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHS 720 ELDR++ R + EVVWG DAEL+ T +AQ LFA+EVALYRL+ SWG++P ++GHS Sbjct: 4752 VCAELDRYVDRSVGEVVWGDDAELIGETVYAQAGLFALEVALYRLIASWGVKPDYLLGHS 4811 Query: 721 VGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAA 780 +GEL+AA+V+G RGRLMQ LP GGVM AV A E E+ PLL + VSVAA Sbjct: 4812 IGELAAAYVAGVWSLEDAARVVAARGRLMQGLPSGGVMVAVAASEGEVLPLLADAVSVAA 4871 Query: 781 VNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQF-RAVADEVY 839 VN P SVV+SG +AV V D L +G R RR+ VSHAFHS M+ ML +F + V Sbjct: 4872 VNAPESVVVSGDEDAVRAVADVL--RGVRTRRVRVSHAFHSARMDGMLAEFGEVLLAGVE 4929 Query: 840 AGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGG 899 P++PV+SNVTG++ E+ S +YWVRH+RE VRFAD + G F+E+GP G Sbjct: 4930 FHAPSLPVVSNVTGEVAGEELCSPEYWVRHVRETVRFADGLDTLRELGVGSFLELGPDGT 4989 Query: 900 LTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGL 959 L +L + +P LR+DRPEP DW +V GG+RV L Sbjct: 4990 LAALTDGD-------GLPVLRRDRPEPLSLMAALGGLYVRGVGVDWGAVFP--GGRRVDL 5040 Query: 960 PTYAFAHERFWL 971 PTYAF +RFWL Sbjct: 5041 PTYAFQRQRFWL 5052 Score = 662 bits (1709), Expect = 0.0 Identities = 418/1068 (39%), Positives = 558/1068 (52%), Gaps = 53/1068 (4%) Query: 1093 LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFP 1152 ++H +N A A R R+ DE IA+VGM CR+P P W+L+ G I E P Sbjct: 1 MNHPDPENGPADDPAPRKRMEPDEAIAVVGMSCRFPQA-PDPEAFWRLLNEGISAISEVP 59 Query: 1153 PDRGWDIERLFDPDPDALGKT-------------------YTRHGGFVSDVADFDPGFFG 1193 R W +R P DA RHGGF+ DV FDP FFG Sbjct: 60 AGR-WIDDRPAPPGTDAPSTPPGTDDPSTSLAADASSTPPAVRHGGFIDDVDRFDPAFFG 118 Query: 1194 ISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--LGTSQAQ 1251 ISP EA+AMDPQQRL+LE +WE LEDAGI P LRG++ G F+G D YG + Sbjct: 119 ISPREAVAMDPQQRLILELAWEGLEDAGIVPATLRGATVGAFIGAGSDDYGSLIRARGRS 178 Query: 1252 WYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGS 1311 + TG + + R+S+ GL+GP+++VD A +SSLVA+H+A SLR GE LALAGG Sbjct: 179 HHTLTGTQRGMLANRLSHVFGLSGPSLTVDAAQASSLVAVHMAVESLRRGESRLALAGGV 238 Query: 1312 TVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLA 1371 + + + L+ DGRC F A+G EG G++VL+ LSDA G V Sbjct: 239 NLNLSAETAADIAAFGALSPDGRCFTFDARANGYVRGEGGGLVVLKPLSDALADGDTVYC 298 Query: 1372 ILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEA 1431 ++ GSAVN DG LTAP Q++V+ A AGI+ A V VE HGTGT LGDP EA Sbjct: 299 VIEGSAVNNDGGGVSLTAPDPDGQRQVLRLAQRRAGISPAAVQYVELHGTGTALGDPAEA 358 Query: 1432 QALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPS 1491 +AL A +GR + P+ LGS+K+N+GH +AAAG+AG++K A+ H+ LPA L+ P+ Sbjct: 359 EALGAVFGR--SGGGPVQLGSVKTNIGHLEAAAGIAGLLKTALAIHHRQLPAGLNYRTPN 416 Query: 1492 AHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH------------XXXXXX 1539 + +++ EWP R AGVSSFG+ GTN H Sbjct: 417 PRIPMGELNLEMRLAPGEWPKPDNR-LVAGVSSFGMGGTNCHVVLAEPPAWASSHASAHH 475 Query: 1540 XXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 1599 P L +S +AA + QA RL ++ R + D+ +SL TTR+ Sbjct: 476 PEPEAVPAPTLAPIPLPLPLSGVSAAALRGQAMRLRPYLE--RSPNLTDLAFSLATTRTS 533 Query: 1600 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 1659 F+HRAV++ + GL + EG G+ G A GK F F GQG+Q LGMG EL Sbjct: 534 FDHRAVLISGQATDAAHGLDALAEGGAAAGLVMGTARAAGKLAFAFAGQGSQRLGMGGEL 593 Query: 1660 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 1719 A +P LD HL RPLR+V+ G DAELL+ T +AQ LFAVEVAL+RLLE Sbjct: 594 SAAFPVFAQALDEVCTALDAHLDRPLRDVIHGDDAELLDRTVYAQAGLFAVEVALFRLLE 653 Query: 1720 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 1779 +G+ P L++GHS+GE+SAAHV+G RGRLMQA+ G M +++A E E Sbjct: 654 DFGLVPDLLIGHSLGEVSAAHVAGVLSLADAAAFVAARGRLMQAVTEPGAMVSLEATEDE 713 Query: 1780 LRPLL--------GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAF 1831 + L G +V VAAVNGP + V+SG AV + +GRR +RL SHAF Sbjct: 714 VTRTLMAGGASDDGVRVCVAAVNGPTATVISGDERAVLDLAAEWTRRGRRTKRLRTSHAF 773 Query: 1832 HSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTG-QLVAEDYGSADYWVRHIREAVRFAD 1890 HS ++P+L++ R +A+ + P IP++SNVTG + AE+ S +YWVRH+R VRF D Sbjct: 774 HSPHLDPVLDELRHIAESLTYQAPRIPLVSNVTGRRATAEELCSPEYWVRHVRRTVRFLD 833 Query: 1891 SVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXX 1950 V G T VE+GP L++L + L + V TLR+DRPEP Sbjct: 834 GVRCLEGEGVTTIVELGPDKALSTLARDCLTGPGTL-VGTLRRDRPEPQALVTALAELYA 892 Query: 1951 XXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXX 2010 W +++ GG+R+ LPTYAF +R+W + + Sbjct: 893 SGVEVAWDPLVS--GGRRIPLPTYAFQRQRYWFSAP-GAEGGDTSAHGVTSGPERTDTGL 949 Query: 2011 XXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLS 2070 + L VL MV H A VLG + A + A F G S++ Sbjct: 950 SPDEALDEGPSNSKVLDTGLSGGEVLGMVRAHAAVVLGYETANAIGAEHTFKQLGFDSIT 1009 Query: 2071 AVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATP 2118 AVEL RL T + L T FDYPTPT LA+HL LH + A P Sbjct: 1010 AVELCERLGEATALPLPGTLLFDYPTPTALAEHLHRRLHGRTDEQAVP 1057 Score = 555 bits (1430), Expect = e-155 Identities = 367/954 (38%), Positives = 498/954 (52%), Gaps = 43/954 (4%) Query: 37 RDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGGDGSQRSADSDTGCA 96 + LG SI + + L + + +P ++D P+ + L +R A Sbjct: 1001 KQLGFDSITAVELCERLGEATALPLPGTLLFDYPTP-----TALAEHLHRRLHGRTDEQA 1055 Query: 97 VLGNGPT---NEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRL----GAAA 149 V PT +P+ ++GM CRF G+ H LW + + + AI+ +P+ R G Sbjct: 1056 VPATVPTPAGGDPVVIVGMGCRFPGRAHSPEDLWRIVVDGEDAISGFPSDRGWDLDGLYH 1115 Query: 150 ADWLGDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGI 206 D D T Y G FL D FD FF I P EAA MDPQQRLLLETSW ALE AGI Sbjct: 1116 PD--PDRSGTSYARDGGFLYDAAEFDAGFFGISPREAAAMDPQQRLLLETSWEALERAGI 1173 Query: 207 LPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSL 266 + +K S TGVF+G SS Y G + + TG ++S+ + R+SY L + GP++ Sbjct: 1174 PAEHIKGSSTGVFIGASSVGYAA---DAGEEAEGYQLTGTAASVASGRVSYTLGLEGPAV 1230 Query: 267 VIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAF 326 +DTACSSSLVA HLA +SL +GEC LA+ G V+ +P ++ F ++ G C+AF Sbjct: 1231 TVDTACSSSLVALHLAVQSLRAGECSLALAGGVTVMATPAMFVEFSRQRGLATDGRCKAF 1290 Query: 327 DARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISV 386 A ADG EG GV+V+ERLSDA R G VLAV+ GSAVNQDG SNG+ APN +Q V Sbjct: 1291 AAAADGTGWAEGVGVLVVERLSDAERNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRV 1350 Query: 387 LDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIG 446 + A A + +++D VEAHG GT++GD IEA AL +G+ R A +PL +GS+K NIG Sbjct: 1351 IRQALVSAGLVASDVDAVEAHGYGTTLGDPIEAQALLATYGQDRDADRPLWLGSVKSNIG 1410 Query: 447 HLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPR 506 H + AAG+AG+IK V+ ++ G L + + +P++ ++ + ++ E WP V R Sbjct: 1411 HTQAAAGVAGVIKMVMAMRHGVLPQTLHVDEWSPHVDWSGGRVELLTEATPWPMTV---R 1467 Query: 507 RAGVSSFGFGGTNAH----XXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRL 562 RAGVSSFG GTNAH +AWV+S + AG+ AQA RL Sbjct: 1468 RAGVSSFGVSGTNAHIILEQAPETAQPTRPIPEGDTEVAAVAWVLSGQGEAGLRAQAERL 1527 Query: 563 LEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGV 622 F A +VG+SL +TR+ HRAVVVGAGRDELL G+ V G GV G Sbjct: 1528 RAFTAASPCPTPAEVGWSLASTRTTLSHRAVVVGAGRDELLRGVDAVANGMAAPGVVRGT 1587 Query: 623 AMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADA 682 P G VFVFPGQG+QW+GM EL L + L +V+ D Sbjct: 1588 GAP-GDVVFVFPGQGSQWVGMALELVESSSVFAGRLGECAEALGPLVEWSLWDVL--GDE 1644 Query: 683 ELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXX 742 L+ + QP L+AV V+L L S+G+ P V+GHS GE++AA V+G Sbjct: 1645 VALSRVDVVQPVLWAVMVSLAELWRSFGVVPSAVVGHSQGEIAAACVAGGLSLEDGARVV 1704 Query: 743 XMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDR 802 +R R + AL G G M +V LR G +SVAAVNGP S V+SG EA+ V++ Sbjct: 1705 ALRSRALLALSGRGGMVSVPVSADRLRDRAG--LSVAAVNGPVSTVVSGPVEALDAVLEE 1762 Query: 803 LAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGS 862 +R+ V +A HSV +E + E V +P S VTG+L+ Sbjct: 1763 FP----EAKRIPVDYASHSVQVEEIREGLAEALASVRPRTGEVPFYSTVTGRLMDTSELD 1818 Query: 863 ADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEES-----LAQVSVVAVP 917 A+YW R++RE V F +V G T FVE P LT I+++ ++ Sbjct: 1819 AEYWYRNLRETVEFQSTVEHLMREGHTVFVEASPHPVLTVGIQDTADATDTTHTDILVTG 1878 Query: 918 TLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 +LR+D DW + AG V LPTYAF ERFWL Sbjct: 1879 SLRRDDGTVQRFLTSLAELHVRGVRIDWGPLFAGV--SPVELPTYAFQRERFWL 1930 Score = 550 bits (1417), Expect = e-153 Identities = 358/959 (37%), Positives = 498/959 (51%), Gaps = 39/959 (4%) Query: 28 AEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAH---DVIKS-VLGGD 83 A ++ +P R LG S+ + + L+ G+ +P ++D+PS D+++S +LGG Sbjct: 2450 AAIDPTVPFRRLGFDSLTAVELRTRLNAATGLRLPATLLFDHPSCRAVADLLRSELLGGR 2509 Query: 84 GSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPAR 143 + S T A +G ++EPIA++ M+CRF G + LW ++E + ++++P Sbjct: 2510 SGPLAVPSATEAAPVGAVASDEPIAIVAMSCRFPGGIESPEDLWRVVSEGREVLSDFPDD 2569 Query: 144 RLGAAAA--DWLGDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSW 198 R A D D T Y G FL D FD + F I P EA MDPQQRLLLE++W Sbjct: 2570 RGWDVEALYDPDPDRPRTSYVRTGAFLHDAAEFDPELFGISPREALAMDPQQRLLLESAW 2629 Query: 199 AALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYF 258 LE A + +++ S TGVF+G Y G + TG ++S+++ R++Y Sbjct: 2630 QVLERARMASTSMRSSRTGVFIGGWGQGYPSASDEG------YALTGAATSVMSGRIAYA 2683 Query: 259 LDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVS 318 L + GP+L +DTACSSSLVA HLA ++L GEC LA+ G V+ +P + F ++ Sbjct: 2684 LGLEGPALTVDTACSSSLVALHLASEALRRGECSLALAGGVTVMATPSTFVEFSRQRGLA 2743 Query: 319 PTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAP 378 P G C+AF ADG GEG G+++LERLSDA R G VLAV+ GSAVNQDG SNG+ AP Sbjct: 2744 PDGRCKAFAGAADGTGWGEGVGMLLLERLSDAERNGHRVLAVVRGSAVNQDGASNGLTAP 2803 Query: 379 NPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMI 438 N +Q V+ A A + ++D VEAHGTGT++GD IEA AL +G+ R A +PL + Sbjct: 2804 NGPSQQRVIRQALANARLSTVDVDVVEAHGTGTTLGDPIEAQALLATYGQDRDADRPLWL 2863 Query: 439 GSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEW 498 GS+K NIGH + AAG+AG+IK V+ ++ G L + + P P + + + ++ E EW Sbjct: 2864 GSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPTPKVDWTTGAVELLTEPAEW 2923 Query: 499 PAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXG-PGVLAWVVSARTAAGVGA 557 P GRPRRAGVS+FG GTNAH P + WV+S A + Sbjct: 2924 PQ-EGRPRRAGVSAFGVSGTNAHVILEQAPEVAAERRQGRDEPVAVPWVLSGANEAALRG 2982 Query: 558 QAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGL--AEVVEGRPG 615 Q RL FV LD DVG+SL +TR+L +R VVVGA EL GL AEVV Sbjct: 2983 QIERLRAFVDDNPTLDPVDVGWSLTSTRALLPYRTVVVGADLAELRHGLDTAEVV----- 3037 Query: 616 VGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLRE 675 G A P V VFPGQG+QW+GM EL L + L + Sbjct: 3038 -----GAAEPDRGAVLVFPGQGSQWVGMALELVESSSVFAGRLGECAAALGPLVEWSLWD 3092 Query: 676 VVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXX 735 V+ D L+ + QP L+AV V+L L S+G+ P V+GHS GE++AA V+G Sbjct: 3093 VL--GDEVALSRVDVVQPVLWAVMVSLAELWRSFGVVPSAVVGHSQGEIAAACVAGALSL 3150 Query: 736 XXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREA 795 +R R + AL G G M +V LR G +SVAAVNGP S V+SG EA Sbjct: 3151 EDGARVVALRSRALLALSGRGGMVSVPVSADRLRGRAG--LSVAAVNGPVSTVVSGPVEA 3208 Query: 796 VSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQL 855 + V++ +R+ V +A HSV +E + E V +P S VTG+L Sbjct: 3209 LDAVLEEFP----EAKRIPVDYASHSVQVEEIREGLAEALASVRPRTGEVPFYSTVTGRL 3264 Query: 856 VAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEES--LAQVSV 913 + +YW R++RE V F +V G T FVE P LT I+++ + Sbjct: 3265 MDTVELDGEYWYRNLRETVEFRSAVEGLLELGHTVFVEASPHPVLTVGIQDTADATDTDI 3324 Query: 914 VAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 + +LR+D +W G V LPTYAF RFW A Sbjct: 3325 LVTGSLRRDDGGLTSFLTALARLHVRGVAVEWRDAFTGLDAHAVELPTYAFQRRRFWAA 3383 Score = 92.0 bits (227), Expect = 9e-16 Identities = 78/258 (30%), Positives = 114/258 (44%), Gaps = 31/258 (12%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 +L G+++AE+Q +L +V EH A VLG A +DA + F + G SL+AVELRNR+ Sbjct: 4094 QLAGVTEAERQNRILRLVREHVAGVLGHASAESVDASRTFQEIGFDSLTAVELRNRISAA 4153 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTD----LFLQTC--- 2134 GV L AT FD+PTP LA+ +L+ + PT A + V A+ D + +C Sbjct: 4154 IGVRLPATAVFDHPTPRLLAERVLAEVWGSLPTAA--PIMPVSAVDDEPIVIVGMSCRFP 4211 Query: 2135 -DAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDVAVVCLPTLTVLSSPH 2193 G +D W +V A + + T R W ++ L+GG+ + Sbjct: 4212 GGVGSPEDLWHLVNSATDAVSALPT---DRGW-DLATLSGGKGGAGA------SYAQDGG 4261 Query: 2194 AYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGAAQAILHAVGDHPHLVLAGYS 2253 D A AG + DP L L A + G P L G Sbjct: 4262 FLYDAAEFDAGFFGISPREATAMDPQQRL-------LLETAWEVFERAGIAPD-TLKGSR 4313 Query: 2254 SG---GVLAHALGSYLAE 2268 +G GV+ H GS+L + Sbjct: 4314 TGVFTGVMYHDYGSWLTD 4331 Score = 80.5 bits (197), Expect = 3e-12 Identities = 42/83 (50%), Positives = 52/83 (62%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+ +S E+ AVL +V AAVLG A +D + F + G SL+AVELRNRL T Sbjct: 5555 RLRDMSRLERDRAVLELVRAQVAAVLGHAKPASVDPSRTFQEVGFDSLTAVELRNRLATA 5614 Query: 1070 TGVTLSATTAFDYPTPTQLADHL 1092 TGV A+ FDYPTP LADH+ Sbjct: 5615 TGVPFPASVIFDYPTPAALADHV 5637 Score = 80.5 bits (197), Expect = 3e-12 Identities = 42/83 (50%), Positives = 52/83 (62%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+ +S E+ AVL +V AAVLG A +D + F + G SL+AVELRNRL T Sbjct: 5555 RLRDMSRLERDRAVLELVRAQVAAVLGHAKPASVDPSRTFQEVGFDSLTAVELRNRLATA 5614 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 TGV A+ FDYPTP LADH+ Sbjct: 5615 TGVPFPASVIFDYPTPAALADHV 5637 Score = 66.6 bits (161), Expect = 4e-08 Identities = 38/87 (43%), Positives = 50/87 (57%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL +S A+Q ++ +V EH A +LG G A +D F G SL+AVELR RL Sbjct: 2419 RLAEVSTADQDRTLVDLVREHAAELLGHHGPAAIDPTVPFRRLGFDSLTAVELRTRLNAA 2478 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L AT FD+P+ +AD L S L Sbjct: 2479 TGLRLPATLLFDHPSCRAVADLLRSEL 2505 >tr|Q1WEK9|Q1WEK9_9ACTO Tax_Id=367779 (merA)SubName: Full=Polyketide synthase;[Streptomyces sp. NRRL 30748] Length = 5712 Score = 1436 bits (3716), Expect = 0.0 Identities = 874/1947 (44%), Positives = 1098/1947 (56%), Gaps = 111/1947 (5%) Query: 104 NEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETI--- 160 +E +AV+GM+CRF Q W L+E SAI E PA R G ++ + Sbjct: 21 DEAVAVVGMSCRFP-QAPDPEAFWRLLSEGISAIGEVPAGRWTDDQPTPSGTDERSTPPA 79 Query: 161 --YGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGV 218 G F++DV+ FD FF I P EAA MDPQQRL+LE +W LE AGI+P TL+ + G Sbjct: 80 IRRGGFIDDVDRFDPAFFGISPREAAAMDPQQRLMLELAWEGLEDAGIVPATLRGATVGA 139 Query: 219 FVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVA 278 F+G S DY L+ GR TG +IANRLS+ ++GPS+ +D A +SSLVA Sbjct: 140 FIGAGSDDYASLIRARGRSHHTL--TGTQRGMIANRLSHVFGLSGPSVTVDAAQASSLVA 197 Query: 279 AHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEG 338 H+A +S+ GE LA+ G N+ +S E G +SP G C FDARA+G VRGEG Sbjct: 198 VHMAVESVRRGESRLALAGGVNLNLSAETAADIAAFGALSPDGRCFTFDARANGYVRGEG 257 Query: 339 CGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDP 398 G+VVL+ LSDA G TV V+ GSAVN DG + AP+P Q VL A + A I P Sbjct: 258 GGLVVLKPLSDALADGDTVYCVIEGSAVNNDGGGASLTAPDPDGQRRVLRLAQRRAAISP 317 Query: 399 AEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLI 458 + YVE HGTGT++GD EA ALG VFGR A+P+ +GS+K NIGHLE AAGIAGL+ Sbjct: 318 EAVQYVELHGTGTALGDPAEAAALGAVFGRS--GARPVQLGSVKTNIGHLEAAAGIAGLL 375 Query: 459 KTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGT 518 KT L + QL + PNP IP EL L + EWP R AGVSSFG GGT Sbjct: 376 KTALAIHHRQLPAGLNYRTPNPRIPMGELNLEMRLAPGEWPKPDDR-LVAGVSSFGMGGT 434 Query: 519 NAHXXXXXXXXXXXXXXXXXGP-------GVLAWV------------------------- 546 N H P + A V Sbjct: 435 NCHVLLAEPLVGVPSHASAHAPEPDSLPSSIPAPVPVPVPVPAPVPVPAPAPAPAPVPVP 494 Query: 547 ----VSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDEL 602 +S +AA + QA RL ++ L D+ +SL T R+ F+HRAV++ + Sbjct: 495 VPLPLSGVSAAALRGQAMRLRPYLERSPNLT--DLSFSLATARTSFDHRAVLITGQAADA 552 Query: 603 LAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXX 662 GL +VEG G+ +G A GK F F GQG+Q LGMGREL A +P Sbjct: 553 AHGLDALVEGGTVAGLVTGTARAAGKLAFAFAGQGSQRLGMGRELGAVFPVFAQALDEVC 612 Query: 663 XELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVG 722 LD HL RPLR+V+ G DAE LN T +AQ LFAVEVAL+RLLE +G+ P L++GHS+G Sbjct: 613 TALDAHLDRPLRDVIHGDDAEPLNRTVYAQAGLFAVEVALFRLLEDFGLVPDLLIGHSLG 672 Query: 723 ELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL--------GE 774 E+SAAHV+G RGRLMQA+ G M +++A E E+ L G Sbjct: 673 EVSAAHVAGVLSLADAATFVAARGRLMQAVTEPGAMVSLEATEDEVTRTLMAGGASDDGA 732 Query: 775 QVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAV 834 +V VAAVNGP + V+SG AV + A +GR+ +RL SHAFHS ++P+L++ R + Sbjct: 733 RVCVAAVNGPTATVISGDERAVLDLAVEWAGRGRKTKRLRTSHAFHSPHLDPVLDELRHI 792 Query: 835 ADEVYAGRPAIPVISNVTGQ-LVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVE 893 A+ + P IP++SNVTG+ AE+ S +YWVRH+R VRF D V G T +E Sbjct: 793 AESLTYRAPRIPLVSNVTGRRATAEELCSPEYWVRHVRRTVRFLDGVRCLEDEGVTTILE 852 Query: 894 VGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCG 953 +GP LT+L + L + V TLR+DRPEP W+ +++G Sbjct: 853 LGPDKALTTLARDCLTGPGTL-VGTLRRDRPEPQALVTALAELYVSGVEVAWSPLVSG-- 909 Query: 954 GQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQG 1013 G+R+ LPTYAF +R+W + G Sbjct: 910 GRRIPLPTYAFQRQRYWFS-----------------APGPESGTTPGHGVTSGRERTDTG 952 Query: 1014 LSDAEQQ------AAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLK 1067 LS E L MV H A VLG A + A F G S++AVEL RL Sbjct: 953 LSGDEAPDTGPSGGETLGMVRAHAAVVLGYASATAIGAEHTFKQLGFDSITAVELCERLG 1012 Query: 1068 TLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 T + L T FDYPTP LA+HL LH + A A +P+ IVGMGCR+ Sbjct: 1013 AATALPLPGTLLFDYPTPAALAEHLHRRLHGRTDEQAAPATVPTPDGGDPVVIVGMGCRF 1072 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PG SP LW++VA G D I FP DRGWD+ L+ PDPD G +Y R GGF+ D A+F Sbjct: 1073 PGRAHSPEDLWRIVADGEDAISGFPSDRGWDLAGLYHPDPDHPGTSYARDGGFLYDAAEF 1132 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGT 1247 D GFFGISP EA AMDPQQRLLLETSWEALE AGI + ++GSSTGVF+G GY Sbjct: 1133 DAGFFGISPREAEAMDPQQRLLLETSWEALERAGIPAEHIKGSSTGVFIGASSVGYAADA 1192 Query: 1248 SQA-QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLA 1306 +A + Y TG SVASGR+SY LGL GPA++VDTACSSSLVALHLA SLRAGEC LA Sbjct: 1193 GEAAEGYQLTGTAASVASGRVSYTLGLEGPAVTVDTACSSSLVALHLAVQSLRAGECSLA 1252 Query: 1307 LAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAG 1366 LAGG TV+ATP++F+ FSRQRGLA DGRCKAFA AADGTG++EG G+LV++RLSDA R G Sbjct: 1253 LAGGVTVMATPAMFVEFSRQRGLAMDGRCKAFAAAADGTGWAEGVGVLVVERLSDAERNG 1312 Query: 1367 QPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLG 1426 VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+ AG+ +DVD VEAHGTGT LG Sbjct: 1313 HRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLVASDVDAVEAHGTGTTLG 1372 Query: 1427 DPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLH 1486 DPIEAQALLATYG+ D PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP TLH Sbjct: 1373 DPIEAQALLATYGQGRDADRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLH 1432 Query: 1487 IDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXX 1546 +D+PS HVDWS G V+LLT WP G RRAGVSSFGVSGTNAH Sbjct: 1433 VDEPSTHVDWSGGRVELLTGTTPWP-TTGGLRRAGVSSFGVSGTNAH----VILEQVPET 1487 Query: 1547 XXXXGP--------GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRS 1598 GP +AWV+S + G+ AQA RL F+ A +VG+SL +TR+ Sbjct: 1488 ARPTGPIGEDDGEAAPVAWVLSGQGETGLRAQAERLCAFMAADTRPTPAEVGWSLASTRA 1547 Query: 1599 LFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRE 1658 HRAVVVGAGRDELL G+ V G P GV G G VFVFPGQG+QW+GM E Sbjct: 1548 TLSHRAVVVGAGRDELLRGVNAVANGTPVPGVVRGTG-ASGDVVFVFPGQGSQWVGMALE 1606 Query: 1659 LCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLL 1718 L P L + L +V+ D + + QP L+AV V+L L Sbjct: 1607 LVESSPVFARRLGDCADALAPFVEWSLFDVL--GDEVAIGRVDVVQPVLWAVMVSLAELW 1664 Query: 1719 ESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQ 1778 S+G+ P V+GHS GE++AA V+G +R R + AL G G M +V Sbjct: 1665 RSFGVVPSAVVGHSQGEIAAACVAGALTLEDGARVVALRSRALLALSGRGGMVSVPVSAD 1724 Query: 1779 ELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEP 1838 LR +G +SVAAVNGP S V+SGA E V++ + A+ +R+ V +A HSV +E Sbjct: 1725 RLRDRVG--LSVAAVNGPASTVVSGAVE----VLEAVLAEFPEAKRIPVDYASHSVQVEG 1778 Query: 1839 MLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSA 1898 + E V +P S VTG+L+ A+YW R++RE V F +V Sbjct: 1779 IREGLAEALAPVRPRTGQVPFYSTVTGRLMDTIELDAEYWYRNLRETVEFQSTVEHLMRQ 1838 Query: 1899 GATRFVEVGPAGGLTSLIEES--LAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXD 1956 G T FVE P LT ++++ +V +LR+D D Sbjct: 1839 GHTVFVEASPHPVLTIGVQDTADTTDTDIVVTGSLRRDDGTVQRFLTSLAELHVRGVRID 1898 Query: 1957 WASVLAGCGGQRVGLPTYAFAHERFWL 1983 W + AG V LPTYAF ERFWL Sbjct: 1899 WGPLFAGV--SPVELPTYAFQRERFWL 1923 Score = 972 bits (2513), Expect = 0.0 Identities = 540/983 (54%), Positives = 642/983 (65%), Gaps = 32/983 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 +L G+++AE+Q ++ +V EH A VLG A +DA + F + G SL+AVELRNR+ Sbjct: 4091 QLAGVTEAERQHQIMRLVQEHVAGVLGHASAELVDASRTFQEIGFDSLTAVELRNRISAA 4150 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRI--DEPIAIVGMGCRY 1127 TG+ L AT FD+PTP LA+ +L+ + S P AA V DEPI IVGM CR+ Sbjct: 4151 TGIRLPATAVFDHPTPRLLAERVLAEV---GGSLPTAAPIAPVSAVDDEPIVIVGMSCRF 4207 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGGV SP LW+LV S D + P DRGWD+ L A G +Y R GGF+ D A+F Sbjct: 4208 PGGVESPEDLWRLVHSATDAVSALPTDRGWDLATLSGAKGGA-GASYARDGGFLYDAAEF 4266 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGT 1247 D GFFGISP EA AMDPQQRLLLE +WE E AGI P L+GS TGVF G+ YG Sbjct: 4267 DAGFFGISPREATAMDPQQRLLLEAAWEVFERAGIAPDTLKGSRTGVFTGVMYHDYGSWL 4326 Query: 1248 SQA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGEC 1303 + + Y TG SVASGR++Y GL GPA++VDTACSSSLVALHLAA SLR GEC Sbjct: 4327 TDVPEDVEGYLGTGIAGSVASGRLAYTFGLEGPALTVDTACSSSLVALHLAAESLRRGEC 4386 Query: 1304 DLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDAR 1363 LALAGG TVLATP +F+ F+RQ GLA DGRCK FA ADGTG+SEG G+L+++RLSDA Sbjct: 4387 SLALAGGVTVLATPQVFVEFTRQGGLAPDGRCKPFAAGADGTGWSEGVGLLLVERLSDAE 4446 Query: 1364 RAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGT 1423 R G PVLA+++GSAVNQDGASNGLTAP+GP+QQRVI AL++AG+ DVD VEAHGTGT Sbjct: 4447 RNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLAARDVDAVEAHGTGT 4506 Query: 1424 RLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPA 1483 LGDPIEAQALLATYG+ PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP Sbjct: 4507 TLGDPIEAQALLATYGQGRDVGQPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPR 4566 Query: 1484 TLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXX 1543 TLH+D+PS HVDWS G V+LL E WP VGRPRRAGVSSFG SGTNAH Sbjct: 4567 TLHVDEPSPHVDWSAGAVELLGEHMGWPE-VGRPRRAGVSSFGASGTNAHVILEQAPDMA 4625 Query: 1544 XXXXXXXGPG---VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLF 1600 + WV SA AG+ AQA RL F +LD DVG+SL T R+ Sbjct: 4626 GEPEQRPERNELPAIPWVFSAGDEAGLRAQAVRLRAFADRNPDLDPVDVGWSLATGRAGL 4685 Query: 1601 EHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELC 1660 HRAVVVGAGR ELL L EG P V GV + GG V +F GQG+Q LGMGR L Sbjct: 4686 SHRAVVVGAGRGELLGAL----EGVPVV----GVPVVGGLGV-LFAGQGSQRLGMGRGLY 4736 Query: 1661 AGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLES 1720 GYP +LD+HL RP+ EVVWG DA L+ T +AQ LFA+EVALYRL+ S Sbjct: 4737 EGYPVFAAVWDEVCAQLDQHLDRPVGEVVWGDDAGLVGETVYAQAGLFALEVALYRLIAS 4796 Query: 1721 WGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQEL 1780 WG+R ++GHS+GEL+AA+V+G RGRLMQALP GG M V A E + Sbjct: 4797 WGVRGDYLLGHSIGELAAAYVAGVWSLEDAGRVVVARGRLMQALPSGGAMVGVAASEGVV 4856 Query: 1781 RPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPML 1840 RPLLGE V VAAVNGP SVVLSG +AV VVD LA +G R RRL VSHAFHS M+ ML Sbjct: 4857 RPLLGEGVVVAAVNGPESVVLSGDEDAVEAVVDVLAGRGVRTRRLRVSHAFHSARMDGML 4916 Query: 1841 EQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGA 1900 +F V V P++PV+SNV+G + E+ S +YWVRH+RE VRFAD + G Sbjct: 4917 AEFGEVLRGVEFRAPSVPVVSNVSGAVAGEELCSPEYWVRHVRETVRFADGLDTLRELGV 4976 Query: 1901 TRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASV 1960 F+E+GP G LT+L + VP LR+DRPEP DW +V Sbjct: 4977 GSFLELGPDGTLTALADGD-------GVPVLRRDRPEPLTAMAALGGLYVRGVQIDWDAV 5029 Query: 1961 LAGCGGQRVGLPTYAFAHERFWL 1983 G +RV LPTYAF ERFWL Sbjct: 5030 FP--GARRVDLPTYAFQRERFWL 5050 Score = 832 bits (2148), Expect = 0.0 Identities = 482/990 (48%), Positives = 600/990 (60%), Gaps = 36/990 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL G+S A+Q ++ +V EH A +LG G A +D F G SL+AVELR RL Sbjct: 2411 RLAGVSAADQARTLVDLVREHAAELLGHRGPAAIDPTVPFRQLGFDSLTAVELRTRLNAA 2470 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTR------VRIDEPIAIVGM 1123 TG+ L AT FD+P+ +AD L S L + AA+ T V DEPIAIV M Sbjct: 2471 TGLRLPATLLFDHPSCRAVADLLRSELLGDRPGSLAASSATEAVPAGVVASDEPIAIVAM 2530 Query: 1124 GCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSD 1183 CR+PGG+ +P LW++V+ G DV+ +FP DRGWD++ L+DPDPD G +Y R GGF+ D Sbjct: 2531 SCRFPGGIGTPEDLWRVVSEGRDVLSDFPDDRGWDVDALYDPDPDRPGTSYVRTGGFLHD 2590 Query: 1184 VADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGY 1243 A+FDP FGISP EALAMDPQQRLLLE++W+ LE A + P +LR S TGVF+G +G GY Sbjct: 2591 AAEFDPELFGISPREALAMDPQQRLLLESAWQVLERARMAPTSLRSSRTGVFIGGWGQGY 2650 Query: 1244 GLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGEC 1303 + + YA TG TSV SGRI+Y LGL GPA++VDTACSSSLVALHLA+ +LR GEC Sbjct: 2651 PSASDEG--YALTGAATSVMSGRIAYALGLEGPALTVDTACSSSLVALHLASEALRRGEC 2708 Query: 1304 DLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDAR 1363 LALAGG TV+ATPS F+ FSRQRGLA DGRCK FA AADGTG+ EG GML+++RLSDA Sbjct: 2709 SLALAGGVTVMATPSTFVEFSRQRGLAPDGRCKPFAGAADGTGWGEGVGMLLVERLSDAE 2768 Query: 1364 RAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGT 1423 R G PVLA+++GSAVNQDGASNGLTAP+GP+QQRVI AL+ AG+ +DVD VEAHGTGT Sbjct: 2769 RLGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLVASDVDAVEAHGTGT 2828 Query: 1424 RLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPA 1483 LGDPIEAQALLATYG+D D PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP Sbjct: 2829 TLGDPIEAQALLATYGQDRDADRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPR 2888 Query: 1484 TLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH-----XXXXX 1538 TLH+D+P+ VDWS G V LLTE+ EW GRPRRAGVS+FGVSGTNAH Sbjct: 2889 TLHVDEPTPKVDWSAGAVGLLTESAEW-RQEGRPRRAGVSAFGVSGTNAHVILEQAPKHA 2947 Query: 1539 XXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRS 1598 P + WV+S + AG+ AQ L F LD DVG+SL +TR+ Sbjct: 2948 PGVAAEGRKGRGEPPTVPWVLSGASEAGLRAQIEGLRAFADDNPTLDPADVGWSLASTRA 3007 Query: 1599 LFEHRAVVVGAGRDELLAGL--AEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMG 1656 L +R VVVG DEL GL AEVV G A P V VFPGQG+QW+GM Sbjct: 3008 LLPYRTVVVGTDLDELRRGLDAAEVV----------GAAEPDRGAVLVFPGQGSQWVGMA 3057 Query: 1657 RELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYR 1716 EL P L L V+ D L + QP L+AV V+L Sbjct: 3058 LELVESSPVFAGRMRDCADALAPFAEWSLFGVL--GDEVALGRVDVVQPVLWAVMVSLAE 3115 Query: 1717 LLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAG 1776 L S+G+ P +V+GHS GE++AA V+G +R R + AL G G M +V Sbjct: 3116 LWRSFGVVPSVVVGHSQGEIAAACVAGGLSLEDGARVVALRSRALLALSGRGGMVSVPVS 3175 Query: 1777 EQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLM 1836 LR +G +SVAAVNGP S V+SGA E V++ + A+ +R+ V +A HSV + Sbjct: 3176 ADRLRGRVG--LSVAAVNGPVSTVVSGAVE----VLEGVLAEFPGAKRIPVDYASHSVQV 3229 Query: 1837 EPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAH 1896 E + E V +P S VTG+L+ +YW R++RE V F ++ Sbjct: 3230 EGIREGLAEALAPVRPRTGEVPFYSTVTGRLMDTVGLDGEYWYRNLRETVEFQSAIEGLL 3289 Query: 1897 SAGATRFVEVGPAGGLTSLIEES--LAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXX 1954 G T FVE P LT I+++ ++ +LR+D Sbjct: 3290 ELGHTVFVEASPHPVLTVGIQDTAETTDTDILVTGSLRRDGGGLASFLTALARLHVRGVA 3349 Query: 1955 XDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W AG V LPTYAF RFW A Sbjct: 3350 VEWREAFAGLDAHAVDLPTYAFQRRRFWAA 3379 Score = 717 bits (1852), Expect = 0.0 Identities = 433/968 (44%), Positives = 553/968 (57%), Gaps = 42/968 (4%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVI 76 ++A G SAE V+ +++G S+ + + +S GI +P AV+D+P+ + Sbjct: 4111 HVAGVLGHASAELVDASRTFQEIGFDSLTAVELRNRISAATGIRLPATAVFDHPTPRLLA 4170 Query: 77 KSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSA 136 + VL G + + +EPI ++GM+CRF G V LW + A Sbjct: 4171 ERVLAEVGGSLPTAAPIAPV---SAVDDEPIVIVGMSCRFPGGVESPEDLWRLVHSATDA 4227 Query: 137 ITEYPARR----------LGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALM 186 ++ P R G A A + D G FL D FD FF I P EA M Sbjct: 4228 VSALPTDRGWDLATLSGAKGGAGASYARD------GGFLYDAAEFDAGFFGISPREATAM 4281 Query: 187 DPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGG 246 DPQQRLLLE +W E AGI P TLK S TGVF GV DY L + TG Sbjct: 4282 DPQQRLLLEAAWEVFERAGIAPDTLKGSRTGVFTGVMYHDYGSWLTDVPEDVEGYLGTGI 4341 Query: 247 SSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPE 306 + S+ + RL+Y + GP+L +DTACSSSLVA HLA +SL GEC LA+ G VL +P+ Sbjct: 4342 AGSVASGRLAYTFGLEGPALTVDTACSSSLVALHLAAESLRRGECSLALAGGVTVLATPQ 4401 Query: 307 VWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAV 366 V+ F G ++P G C+ F A ADG EG G++++ERLSDA R G VLAV++GSAV Sbjct: 4402 VFVEFTRQGGLAPDGRCKPFAAGADGTGWSEGVGLLLVERLSDAERNGHPVLAVVSGSAV 4461 Query: 367 NQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVF 426 NQDG SNG+ APN +Q V+ A A + ++D VEAHGTGT++GD IEA AL + Sbjct: 4462 NQDGASNGLTAPNGPSQQRVIRQALANAGLAARDVDAVEAHGTGTTLGDPIEAQALLATY 4521 Query: 427 GRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAE 486 G+GR +PL +GS+K NIGH + AAG+AG+IK V+ ++ G L + + P+P++ ++ Sbjct: 4522 GQGRDVGQPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSPHVDWSA 4581 Query: 487 LGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLA-- 544 + ++ E WP V GRPRRAGVSSFG GTNAH L Sbjct: 4582 GAVELLGEHMGWPEV-GRPRRAGVSSFGASGTNAHVILEQAPDMAGEPEQRPERNELPAI 4640 Query: 545 -WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELL 603 WV SA AG+ AQA RL F +LD DVG+SL T R+ HRAVVVGAGR ELL Sbjct: 4641 PWVFSAGDEAGLRAQAVRLRAFADRNPDLDPVDVGWSLATGRAGLSHRAVVVGAGRGELL 4700 Query: 604 AGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXX 663 L EG P VGV + GG V +F GQG+Q LGMGR L GYP Sbjct: 4701 GAL----EGVPVVGVP----VVGGLGV-LFAGQGSQRLGMGRGLYEGYPVFAAVWDEVCA 4751 Query: 664 ELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGE 723 +LD+HL RP+ EVVWG DA L+ T +AQ LFA+EVALYRL+ SWG+R ++GHS+GE Sbjct: 4752 QLDQHLDRPVGEVVWGDDAGLVGETVYAQAGLFALEVALYRLIASWGVRGDYLLGHSIGE 4811 Query: 724 LSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNG 783 L+AA+V+G RGRLMQALP GG M V A E +RPLLGE V VAAVNG Sbjct: 4812 LAAAYVAGVWSLEDAGRVVVARGRLMQALPSGGAMVGVAASEGVVRPLLGEGVVVAAVNG 4871 Query: 784 PGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRP 843 P SVVLSG +AV VVD LA +G R RRL VSHAFHS M+ ML +F V V P Sbjct: 4872 PESVVLSGDEDAVEAVVDVLAGRGVRTRRLRVSHAFHSARMDGMLAEFGEVLRGVEFRAP 4931 Query: 844 AIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSL 903 ++PV+SNV+G + E+ S +YWVRH+RE VRFAD + G F+E+GP G LT+L Sbjct: 4932 SVPVVSNVSGAVAGEELCSPEYWVRHVRETVRFADGLDTLRELGVGSFLELGPDGTLTAL 4991 Query: 904 IEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYA 963 + VP LR+DRPEP DW +V G +RV LPTYA Sbjct: 4992 ADGD-------GVPVLRRDRPEPLTAMAALGGLYVRGVQIDWDAVFP--GARRVDLPTYA 5042 Query: 964 FAHERFWL 971 F ERFWL Sbjct: 5043 FQRERFWL 5050 Score = 643 bits (1658), Expect = 0.0 Identities = 422/1105 (38%), Positives = 563/1105 (50%), Gaps = 94/1105 (8%) Query: 1107 AVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPD 1166 A R R+ DE +A+VGM CR+P P W+L++ G IGE P R D + P Sbjct: 13 APRKRMEPDEAVAVVGMSCRFPQA-PDPEAFWRLLSEGISAIGEVPAGRWTDDQ----PT 67 Query: 1167 PDALGKTYT----RHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGI 1222 P + T R GGF+ DV FDP FFGISP EA AMDPQQRL+LE +WE LEDAGI Sbjct: 68 PSGTDERSTPPAIRRGGFIDDVDRFDPAFFGISPREAAAMDPQQRLMLELAWEGLEDAGI 127 Query: 1223 DPQALRGSSTGVFVGIYGDGYG--LGTSQAQWYADTGHITSVASGRISYCLGLAGPAISV 1280 P LRG++ G F+G D Y + + TG + + R+S+ GL+GP+++V Sbjct: 128 VPATLRGATVGAFIGAGSDDYASLIRARGRSHHTLTGTQRGMIANRLSHVFGLSGPSVTV 187 Query: 1281 DTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFAD 1340 D A +SSLVA+H+A S+R GE LALAGG + + + L+ DGRC F Sbjct: 188 DAAQASSLVAVHMAVESVRRGESRLALAGGVNLNLSAETAADIAAFGALSPDGRCFTFDA 247 Query: 1341 AADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVIS 1400 A+G EG G++VL+ LSDA G V ++ GSAVN DG LTAP Q+RV+ Sbjct: 248 RANGYVRGEGGGLVVLKPLSDALADGDTVYCVIEGSAVNNDGGGASLTAPDPDGQRRVLR 307 Query: 1401 AALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHS 1460 A A I+ V VE HGTGT LGDP EA AL A +GR P+ LGS+K+N+GH Sbjct: 308 LAQRRAAISPEAVQYVELHGTGTALGDPAEAAALGAVFGRSGA--RPVQLGSVKTNIGHL 365 Query: 1461 QAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRA 1520 +AAAG+AG++K A+ H+ LPA L+ P+ + +++ EWP R A Sbjct: 366 EAAAGIAGLLKTALAIHHRQLPAGLNYRTPNPRIPMGELNLEMRLAPGEWPKPDDR-LVA 424 Query: 1521 GVSSFGVSGTNAHXXXXXXXXXXXXXXXXXGP-------GVLAWV--------------- 1558 GVSSFG+ GTN H P + A V Sbjct: 425 GVSSFGMGGTNCHVLLAEPLVGVPSHASAHAPEPDSLPSSIPAPVPVPVPVPAPVPVPAP 484 Query: 1559 --------------VSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 +S +AA + QA RL ++ R + D+ +SL T R+ F+HRA Sbjct: 485 APAPAPVPVPVPLPLSGVSAAALRGQAMRLRPYLE--RSPNLTDLSFSLATARTSFDHRA 542 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 V++ + GL +VEG G+ +G A GK F F GQG+Q LGMGREL A +P Sbjct: 543 VLITGQAADAAHGLDALVEGGTVAGLVTGTARAAGKLAFAFAGQGSQRLGMGRELGAVFP 602 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 LD HL RPLR+V+ G DAE LN T +AQ LFAVEVAL+RLLE +G+ Sbjct: 603 VFAQALDEVCTALDAHLDRPLRDVIHGDDAEPLNRTVYAQAGLFAVEVALFRLLEDFGLV 662 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P L++GHS+GE+SAAHV+G RGRLMQA+ G M +++A E E+ L Sbjct: 663 PDLLIGHSLGEVSAAHVAGVLSLADAATFVAARGRLMQAVTEPGAMVSLEATEDEVTRTL 722 Query: 1785 --------GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLM 1836 G +V VAAVNGP + V+SG AV + A +GR+ +RL SHAFHS + Sbjct: 723 MAGGASDDGARVCVAAVNGPTATVISGDERAVLDLAVEWAGRGRKTKRLRTSHAFHSPHL 782 Query: 1837 EPMLEQFRAVADEVYAGRPAIPVISNVTG-QLVAEDYGSADYWVRHIREAVRFADSVCFA 1895 +P+L++ R +A+ + P IP++SNVTG + AE+ S +YWVRH+R VRF D V Sbjct: 783 DPVLDELRHIAESLTYRAPRIPLVSNVTGRRATAEELCSPEYWVRHVRRTVRFLDGVRCL 842 Query: 1896 HSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXX 1955 G T +E+GP LT+L + L + V TLR+DRPEP Sbjct: 843 EDEGVTTILELGPDKALTTLARDCLTGPGTL-VGTLRRDRPEPQALVTALAELYVSGVEV 901 Query: 1956 DWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXX 2015 W+ +++ GG+R+ LPTYAF +R+W + Sbjct: 902 AWSPLVS--GGRRIPLPTYAFQRQRYWFS-----------------APGPESGTTPGHGV 942 Query: 2016 XXXXXXRLQGLSDAE------QQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSL 2069 GLS E L MV H A VLG A + A F G S+ Sbjct: 943 TSGRERTDTGLSGDEAPDTGPSGGETLGMVRAHAAVVLGYASATAIGAEHTFKQLGFDSI 1002 Query: 2070 SAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLH----HQNPTGATPELDRVDA 2125 +AVEL RL T + L T FDYPTP LA+HL LH Q P D D Sbjct: 1003 TAVELCERLGAATALPLPGTLLFDYPTPAALAEHLHRRLHGRTDEQAAPATVPTPDGGDP 1062 Query: 2126 LTDLFLQTCDAGR---DDDGWQIVA 2147 + + + GR +D W+IVA Sbjct: 1063 VVIVGMGCRFPGRAHSPEDLWRIVA 1087 Score = 563 bits (1450), Expect = e-157 Identities = 367/953 (38%), Positives = 505/953 (52%), Gaps = 42/953 (4%) Query: 37 RDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSV---LGGDGSQRSADSDT 93 + LG SI + + L + +P ++D P+ + + + L G +++A Sbjct: 995 KQLGFDSITAVELCERLGAATALPLPGTLLFDYPTPAALAEHLHRRLHGRTDEQAAP--- 1051 Query: 94 GCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWL 153 A + +P+ ++GM CRF G+ H LW +A+ + AI+ +P+ R A + Sbjct: 1052 --ATVPTPDGGDPVVIVGMGCRFPGRAHSPEDLWRIVADGEDAISGFPSDRGWDLAGLYH 1109 Query: 154 GDEQE--TIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILP 208 D T Y G FL D FD FF I P EA MDPQQRLLLETSW ALE AGI Sbjct: 1110 PDPDHPGTSYARDGGFLYDAAEFDAGFFGISPREAEAMDPQQRLLLETSWEALERAGIPA 1169 Query: 209 KTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVI 268 + +K S TGVF+G SS Y G + TG ++S+ + R+SY L + GP++ + Sbjct: 1170 EHIKGSSTGVFIGASSVGYAA---DAGEAAEGYQLTGTAASVASGRVSYTLGLEGPAVTV 1226 Query: 269 DTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDA 328 DTACSSSLVA HLA +SL +GEC LA+ G V+ +P ++ F ++ G C+AF A Sbjct: 1227 DTACSSSLVALHLAVQSLRAGECSLALAGGVTVMATPAMFVEFSRQRGLAMDGRCKAFAA 1286 Query: 329 RADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLD 388 ADG EG GV+V+ERLSDA R G VLAV+ GSAVNQDG SNG+ APN +Q V+ Sbjct: 1287 AADGTGWAEGVGVLVVERLSDAERNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIR 1346 Query: 389 SACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHL 448 A A + +++D VEAHGTGT++GD IEA AL +G+GR A +PL +GS+K NIGH Sbjct: 1347 QALASAGLVASDVDAVEAHGTGTTLGDPIEAQALLATYGQGRDADRPLWLGSVKSNIGHT 1406 Query: 449 EGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRA 508 + AAG+AG+IK V+ ++ G L + + P+ ++ ++ + ++ WP G RRA Sbjct: 1407 QAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSTHVDWSGGRVELLTGTTPWP-TTGGLRRA 1465 Query: 509 GVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP--------GVLAWVVSARTAAGVGAQAG 560 GVSSFG GTNAH GP +AWV+S + G+ AQA Sbjct: 1466 GVSSFGVSGTNAH----VILEQVPETARPTGPIGEDDGEAAPVAWVLSGQGETGLRAQAE 1521 Query: 561 RLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVAS 620 RL F+ A +VG+SL +TR+ HRAVVVGAGRDELL G+ V G P GV Sbjct: 1522 RLCAFMAADTRPTPAEVGWSLASTRATLSHRAVVVGAGRDELLRGVNAVANGTPVPGVVR 1581 Query: 621 GVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA 680 G G VFVFPGQG+QW+GM EL P L + L +V+ Sbjct: 1582 GTG-ASGDVVFVFPGQGSQWVGMALELVESSPVFARRLGDCADALAPFVEWSLFDVL--G 1638 Query: 681 DAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXX 740 D + + QP L+AV V+L L S+G+ P V+GHS GE++AA V+G Sbjct: 1639 DEVAIGRVDVVQPVLWAVMVSLAELWRSFGVVPSAVVGHSQGEIAAACVAGALTLEDGAR 1698 Query: 741 XXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVV 800 +R R + AL G G M +V LR +G +SVAAVNGP S V+SGA E V+ Sbjct: 1699 VVALRSRALLALSGRGGMVSVPVSADRLRDRVG--LSVAAVNGPASTVVSGAVE----VL 1752 Query: 801 DRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDY 860 + + A+ +R+ V +A HSV +E + E V +P S VTG+L+ Sbjct: 1753 EAVLAEFPEAKRIPVDYASHSVQVEGIREGLAEALAPVRPRTGQVPFYSTVTGRLMDTIE 1812 Query: 861 GSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEES--LAQVSVVAVPT 918 A+YW R++RE V F +V G T FVE P LT ++++ +V + Sbjct: 1813 LDAEYWYRNLRETVEFQSTVEHLMRQGHTVFVEASPHPVLTIGVQDTADTTDTDIVVTGS 1872 Query: 919 LRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 LR+D DW + AG V LPTYAF ERFWL Sbjct: 1873 LRRDDGTVQRFLTSLAELHVRGVRIDWGPLFAGV--SPVELPTYAFQRERFWL 1923 Score = 547 bits (1410), Expect = e-153 Identities = 359/963 (37%), Positives = 502/963 (52%), Gaps = 43/963 (4%) Query: 28 AEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAH---DVIKSVLGGDG 84 A ++ +P R LG S+ + + L+ G+ +P ++D+PS D+++S L GD Sbjct: 2442 AAIDPTVPFRQLGFDSLTAVELRTRLNAATGLRLPATLLFDHPSCRAVADLLRSELLGDR 2501 Query: 85 -SQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPAR 143 +A S T G ++EPIA++ M+CRF G + LW ++E + ++++P Sbjct: 2502 PGSLAASSATEAVPAGVVASDEPIAIVAMSCRFPGGIGTPEDLWRVVSEGRDVLSDFPDD 2561 Query: 144 RLGAAAA--DWLGDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSW 198 R A D D T Y G FL D FD + F I P EA MDPQQRLLLE++W Sbjct: 2562 RGWDVDALYDPDPDRPGTSYVRTGGFLHDAAEFDPELFGISPREALAMDPQQRLLLESAW 2621 Query: 199 AALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYF 258 LE A + P +L+ S TGVF+G Y G + TG ++S+++ R++Y Sbjct: 2622 QVLERARMAPTSLRSSRTGVFIGGWGQGYPSASDEG------YALTGAATSVMSGRIAYA 2675 Query: 259 LDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVS 318 L + GP+L +DTACSSSLVA HLA ++L GEC LA+ G V+ +P + F ++ Sbjct: 2676 LGLEGPALTVDTACSSSLVALHLASEALRRGECSLALAGGVTVMATPSTFVEFSRQRGLA 2735 Query: 319 PTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAP 378 P G C+ F ADG GEG G++++ERLSDA R G VLAV++GSAVNQDG SNG+ AP Sbjct: 2736 PDGRCKPFAGAADGTGWGEGVGMLLVERLSDAERLGHPVLAVVSGSAVNQDGASNGLTAP 2795 Query: 379 NPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMI 438 N +Q V+ A A + +++D VEAHGTGT++GD IEA AL +G+ R A +PL + Sbjct: 2796 NGPSQQRVIRQALASAGLVASDVDAVEAHGTGTTLGDPIEAQALLATYGQDRDADRPLWL 2855 Query: 439 GSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEW 498 GS+K NIGH + AAG+AG+IK V+ ++ G L + + P P + ++ + ++ E EW Sbjct: 2856 GSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPTPKVDWSAGAVGLLTESAEW 2915 Query: 499 PAVVGRPRRAGVSSFGFGGTNAH-----XXXXXXXXXXXXXXXXXGPGVLAWVVSARTAA 553 GRPRRAGVS+FG GTNAH P + WV+S + A Sbjct: 2916 -RQEGRPRRAGVSAFGVSGTNAHVILEQAPKHAPGVAAEGRKGRGEPPTVPWVLSGASEA 2974 Query: 554 GVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGL--AEVVE 611 G+ AQ L F LD DVG+SL +TR+L +R VVVG DEL GL AEVV Sbjct: 2975 GLRAQIEGLRAFADDNPTLDPADVGWSLASTRALLPYRTVVVGTDLDELRRGLDAAEVV- 3033 Query: 612 GRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLAR 671 G A P V VFPGQG+QW+GM EL P L Sbjct: 3034 ---------GAAEPDRGAVLVFPGQGSQWVGMALELVESSPVFAGRMRDCADALAPFAEW 3084 Query: 672 PLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSG 731 L V+ D L + QP L+AV V+L L S+G+ P +V+GHS GE++AA V+G Sbjct: 3085 SLFGVL--GDEVALGRVDVVQPVLWAVMVSLAELWRSFGVVPSVVVGHSQGEIAAACVAG 3142 Query: 732 XXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSG 791 +R R + AL G G M +V LR +G +SVAAVNGP S V+SG Sbjct: 3143 GLSLEDGARVVALRSRALLALSGRGGMVSVPVSADRLRGRVG--LSVAAVNGPVSTVVSG 3200 Query: 792 AREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNV 851 A E V++ + A+ +R+ V +A HSV +E + E V +P S V Sbjct: 3201 AVE----VLEGVLAEFPGAKRIPVDYASHSVQVEGIREGLAEALAPVRPRTGEVPFYSTV 3256 Query: 852 TGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEES--LA 909 TG+L+ +YW R++RE V F ++ G T FVE P LT I+++ Sbjct: 3257 TGRLMDTVGLDGEYWYRNLRETVEFQSAIEGLLELGHTVFVEASPHPVLTVGIQDTAETT 3316 Query: 910 QVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERF 969 ++ +LR+D +W AG V LPTYAF RF Sbjct: 3317 DTDILVTGSLRRDGGGLASFLTALARLHVRGVAVEWREAFAGLDAHAVDLPTYAFQRRRF 3376 Query: 970 WLA 972 W A Sbjct: 3377 WAA 3379 Score = 89.0 bits (219), Expect = 8e-15 Identities = 76/258 (29%), Positives = 115/258 (44%), Gaps = 31/258 (12%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 +L G+++AE+Q ++ +V EH A VLG A +DA + F + G SL+AVELRNR+ Sbjct: 4091 QLAGVTEAERQHQIMRLVQEHVAGVLGHASAELVDASRTFQEIGFDSLTAVELRNRISAA 4150 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTD----LFLQTC--- 2134 TG+ L AT FD+PTP LA+ +L+ + PT A + V A+ D + +C Sbjct: 4151 TGIRLPATAVFDHPTPRLLAERVLAEVGGSLPTAA--PIAPVSAVDDEPIVIVGMSCRFP 4208 Query: 2135 -DAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDVAVVCLPTLTVLSSPH 2193 +D W++V A + + T R W ++ L+G + + Sbjct: 4209 GGVESPEDLWRLVHSATDAVSALPT---DRGW-DLATLSGAKGGAGA------SYARDGG 4258 Query: 2194 AYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGAAQAILHAVGDHPHLVLAGYS 2253 D A AG + DP L L AA + G P L G Sbjct: 4259 FLYDAAEFDAGFFGISPREATAMDPQQRL-------LLEAAWEVFERAGIAPD-TLKGSR 4310 Query: 2254 SG---GVLAHALGSYLAE 2268 +G GV+ H GS+L + Sbjct: 4311 TGVFTGVMYHDYGSWLTD 4328 Score = 86.3 bits (212), Expect = 5e-14 Identities = 49/110 (44%), Positives = 64/110 (58%), Gaps = 5/110 (4%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+G+S E+ AVL +V AAVLG A +D + F + G SL+AVELRNRL T Sbjct: 5546 RLRGMSRIERDRAVLELVRAQVAAVLGHAKPASVDPSRTFQEVGFDSLTAVELRNRLATA 5605 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL-----HHQNPTGATPELDRVDAL 2126 TGV + FDYPTPT LADH+ + + ++ GAT LD + L Sbjct: 5606 TGVPFPGSVIFDYPTPTALADHVRARFVPDTDNDEDGGGATSVLDELTRL 5655 Score = 83.6 bits (205), Expect = 3e-13 Identities = 43/83 (51%), Positives = 53/83 (63%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+G+S E+ AVL +V AAVLG A +D + F + G SL+AVELRNRL T Sbjct: 5546 RLRGMSRIERDRAVLELVRAQVAAVLGHAKPASVDPSRTFQEVGFDSLTAVELRNRLATA 5605 Query: 1070 TGVTLSATTAFDYPTPTQLADHL 1092 TGV + FDYPTPT LADH+ Sbjct: 5606 TGVPFPGSVIFDYPTPTALADHV 5628 Score = 70.5 bits (171), Expect = 3e-09 Identities = 53/157 (33%), Positives = 75/157 (47%), Gaps = 16/157 (10%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL G+S A+Q ++ +V EH A +LG G A +D F G SL+AVELR RL Sbjct: 2411 RLAGVSAADQARTLVDLVREHAAELLGHRGPAAIDPTVPFRQLGFDSLTAVELRTRLNAA 2470 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP--------TGATPE-LDRVDALTDLFLQ 2132 TG+ L AT FD+P+ +AD L S L P T A P + D + Sbjct: 2471 TGLRLPATLLFDHPSCRAVADLLRSELLGDRPGSLAASSATEAVPAGVVASDEPIAIVAM 2530 Query: 2133 TC----DAGRDDDGWQIVALAANGRERMTTPVPKREW 2165 +C G +D W++V + GR+ ++ R W Sbjct: 2531 SCRFPGGIGTPEDLWRVV---SEGRDVLSDFPDDRGW 2564 >tr|Q68BG5|Q68BG5_STRHA Tax_Id=1944 (hlsA)SubName: Full=Type I polyketide synthase;[Streptomyces halstedii] Length = 4194 Score = 1410 bits (3650), Expect = 0.0 Identities = 845/1908 (44%), Positives = 1096/1908 (57%), Gaps = 47/1908 (2%) Query: 107 IAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLE 166 IAV+GM+CR G + +G WD L S + G+ + L D E +L+ Sbjct: 7 IAVVGMSCRLPGALD-LGEFWDLLMSSGSGVG-----LPGSDRSRRLDDSHEPRRAGYLQ 60 Query: 167 DVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTD 226 V+ FD FF + P EA MDP+QRL+LE SW ALE+AGI P L S GVF+G S D Sbjct: 61 QVDLFDASFFGLGPQEATAMDPRQRLILELSWEALENAGISPAGLAGSSVGVFLGASGDD 120 Query: 227 YVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSL 286 Y P + G + ++IANR+S+ LD+ GPSL++DTA SSSLVA H+A +S+ Sbjct: 121 YPGAGTVADANPYL--AAGTNRAVIANRVSHALDLTGPSLLVDTAQSSSLVAVHMACESI 178 Query: 287 ASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLER 346 GEC A+V G N+ +S + GVVSP G C FDARA+G V GEG GV+VL+ Sbjct: 179 RRGECTTAIVGGVNLNLSSRRIHMLESLGVVSPDGECFTFDARANGFVPGEGGGVLVLKD 238 Query: 347 LSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEA 406 LS A G V AV+ G+A+N DG + G+ +P+P AQ +V+ A + AD+ P ++ +VE Sbjct: 239 LSAALADGGQVHAVIRGTALNHDGATFGLSSPSPAAQEAVIRQAHRAADVLPGDVRFVEL 298 Query: 407 HGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQR 466 HGTGT GD EA ALG F PL++GS+K NIGHL+ A+G GLIK VL L Sbjct: 299 HGTGTQAGDATEATALGAAFAGDSPRESPLLVGSVKTNIGHLDAASGAVGLIKAVLSLTN 358 Query: 467 GQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGR-PRRAGVSSFGFGGTNAHXXXX 525 +L PS F PNP I LGL V ++ G P +AGVSSFG GG N H Sbjct: 359 RKLPPSRNFAEPNPAIDLPALGLEVATSVRDLAGDSGESPVQAGVSSFGMGGANCHVVVS 418 Query: 526 XXXXXXXXXXXXX-----------GPGVLA-WVVSARTAAGVGAQAGRLLEFVRAGRELD 573 GVL WVVS R GV AQA RL E+V Sbjct: 419 DALDLDTSAPRPSTETASDTPPETSDGVLVPWVVSGRGVDGVRAQAARLREWVLERSADR 478 Query: 574 AGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA--SGVAMPGGKTVF 631 DVG+SL+++RSL R VV+G+ R L+ GLA VEG P GV SG + + VF Sbjct: 479 PVDVGFSLLSSRSLHRDRLVVLGSDRQVLVDGLAAFVEGAPWPGVVGGSGGGVVADRAVF 538 Query: 632 VFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVV-WGADAELLNTTEF 690 VFPGQG+QW+GMGREL A P LD + L +VV G+ A L + Sbjct: 539 VFPGQGSQWVGMGRELYASSPVFRARLDECAAALDPLVDWSLIDVVRGGSGAPGLERVDV 598 Query: 691 AQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQ 750 QP L+AV V+L + ESWG+ P V+GHS GE++AA V+G +R R ++ Sbjct: 599 VQPVLWAVMVSLAAVWESWGVVPAAVVGHSQGEIAAACVAGALSVVDAARVVALRSRALR 658 Query: 751 ALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRV 810 A+ G G M +V E L G+ VS+AAVNGP SVVLSG R A++ VV+RL+A+G R Sbjct: 659 AMAGDGAMVSVALPVAEAEALTGDGVSLAAVNGPSSVVLSGDRSALTPVVERLSAEGVRT 718 Query: 811 RRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHI 870 + + V +A HS ME + ++ + + IP+ S V+ +++ A YW +I Sbjct: 719 KWVPVDYASHSAHMERIHDELLEILSGIVPKTSRIPLYSTVSAEVIDTSVMDAGYWFDNI 778 Query: 871 REAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRPEPFX 928 R VRF ++V + G T FVE+ P L ++++L A+ + +++ TLR+D E Sbjct: 779 RGTVRFHETVQALIADGLTAFVEISPHPVLAMSVQDTLDQAEATGLSIGTLRRDENEEKS 838 Query: 929 XXXXXXXXXXXXXXXDW-ASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXL 987 DW + A ++V LPTYAF +WL + Sbjct: 839 LLTAAAELFVAGLPIDWNTAAFADLDTRQVDLPTYAFQRRPYWLET-------VAQTVRV 891 Query: 988 XXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQ 1047 R+ GL + AV V H AAVLG + +D Sbjct: 892 GAPAAAPTESPEVPGSRSPLAERVAGLPQGARHQAVTDFVRAHAAAVLGHTDHSDIDVAL 951 Query: 1048 AFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAA 1107 F D G S++A E R RL G+ L AT FD+PTP + D LL+ L + + Sbjct: 952 TFRDLGFDSINATEFRLRLGDAAGLRLPATLVFDHPTPAVVVDFLLTRLLGGEADSLPST 1011 Query: 1108 VRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDP 1167 DEP+AIVGM CR+PGGVS+P QLW+LVA G D + P DRGWDIE L+ PDP Sbjct: 1012 RTAASDPDEPVAIVGMACRFPGGVSTPEQLWRLVAEGVDAVSGLPTDRGWDIESLYHPDP 1071 Query: 1168 DALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQAL 1227 D G +Y GGF+ + +FD GFFGISP EALAMDPQQRLLL+TSWEA+E AGIDP +L Sbjct: 1072 DHPGTSYANEGGFLHEAGEFDAGFFGISPREALAMDPQQRLLLQTSWEAVERAGIDPLSL 1131 Query: 1228 RGSSTGVFVGIYGDGYGL------GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVD 1281 +GS TGVF G YG + Y TG+ SV SGR++Y LG GPA++VD Sbjct: 1132 KGSDTGVFTGAMTQDYGPRLHEPDSSGTVDGYMLTGNAGSVMSGRVAYVLGTEGPAVTVD 1191 Query: 1282 TACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADA 1341 TACSSSLVALH AA +LR GEC +ALAGG TV+ATP +F+ FSRQRGLA DGRCKAFA Sbjct: 1192 TACSSSLVALHWAAQALRQGECSMALAGGVTVMATPGMFVEFSRQRGLAPDGRCKAFAAG 1251 Query: 1342 ADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISA 1401 ADGTG++EG GM++++RLSDA+R G P+LA++ SAVNQDGASNGLTAP+GP+QQRVI Sbjct: 1252 ADGTGWAEGVGMVLVERLSDAQRLGHPILAVVRSSAVNQDGASNGLTAPNGPSQQRVIRQ 1311 Query: 1402 ALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQ 1461 ALS AG+T ADVD VEAHGTGT LGDPIEAQALLATYG+D PL LGS+KSN+GH+Q Sbjct: 1312 ALSTAGLTTADVDAVEAHGTGTNLGDPIEAQALLATYGQDRPEGRPLLLGSLKSNIGHTQ 1371 Query: 1462 AAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAG 1521 AAAGVAGVIKMV A+RH +LPATLH+D+PS HVDW+ G V+LLTEA WP RPRRA Sbjct: 1372 AAAGVAGVIKMVMALRHGVLPATLHVDEPSPHVDWASGAVELLTEATAWPE-TDRPRRAA 1430 Query: 1522 VSSFGVSGTNAHXXXXXXXXXXXXXXXXXGPGVLA-WVVSARTAAGVGAQAGRLLEFVRA 1580 VSSFG+SGTNAH GVL WVVS R GV AQA L E+V Sbjct: 1431 VSSFGISGTNAHAILEQAPETDNAAEPVVRDGVLVPWVVSGRGVDGVRAQAAGLREWVLE 1490 Query: 1581 GRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVG-VASGVAMPGG 1639 + A D+G+SL+++RSL R VV+G+ R L+ GLA EG P G V S + Sbjct: 1491 HPQHSATDIGFSLLSSRSLHRDRLVVLGSDRQVLVDGLAAAAEGAPWPGLVQSSGDVSLS 1550 Query: 1640 KTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG-ADAELLN 1698 + VFVFPGQG+QW+GMGREL A P LD + L +VV G + A L Sbjct: 1551 RAVFVFPGQGSQWVGMGRELYASSPVFRARLDECARALDPLVDWSLIDVVRGESGAPGLE 1610 Query: 1699 TTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRG 1758 + QP L+AV V+L + ESWG+ P V+GHS GE++AA V+G +R Sbjct: 1611 RVDVVQPVLWAVMVSLAAVWESWGVVPAAVVGHSQGEIAAACVAGALSVEDAAQVVALRS 1670 Query: 1759 RLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQ 1818 R ++A+ G G M +V E L G+ VS+AAVNGP SVVLSG R A++ VV+ L AQ Sbjct: 1671 RAVRAMAGDGAMVSVALPAAEAEALTGDGVSLAAVNGPSSVVLSGDRSALTPVVEGLTAQ 1730 Query: 1819 GRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYW 1878 G R + + V +A HS ME + ++ + + IP+ S V+ + A YW Sbjct: 1731 GVRTKWVPVDYASHSAHMERIRDELLEILSGIEPKTSRIPLYSTVSAARIDTSRMDASYW 1790 Query: 1879 VRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRP 1936 +IR VRF ++V + G T FVEV P L ++++L A+ + +++ TLR+D+ Sbjct: 1791 FDNIRGTVRFHETVQALIADGLTAFVEVSPHPVLAMSVQDTLDQAEATGLSIGTLRRDQN 1850 Query: 1937 EPFXXXXXXXXXXXXXXXXDW-ASVLAGCGGQRVGLPTYAFAHERFWL 1983 E DW + A +RV LPTYAF ERFWL Sbjct: 1851 EHETLLTAAAELFVAGLPIDWHTAAFADLDTRRVDLPTYAFQTERFWL 1898 Score = 966 bits (2497), Expect = 0.0 Identities = 530/995 (53%), Positives = 649/995 (65%), Gaps = 24/995 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL S E++ +L +V AAVLG G ++ AG+ F + G SL+AVELRNRL T Sbjct: 2467 RLADRSPVERRKTILELVRAQAAAVLGHTGTDRIVAGRPFRELGFDSLTAVELRNRLNTA 2526 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAP---AAAVRTRVRIDEPIAIVGMGCR 1126 TG+ LS+T AFD+PTP + H+LS L S AA DEP+A+VGM CR Sbjct: 2527 TGLKLSSTAAFDHPTPEVITGHILSGLELGGESPDDEAAALGSVPHSHDEPLAVVGMACR 2586 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 PGG +SP +LWQL+ GDVI E P DRGWDIE L+DPDPD G +YTR GGF+ D A+ Sbjct: 2587 LPGGTNSPERLWQLLMERGDVISELPTDRGWDIEGLYDPDPDRPGTSYTRAGGFLYDAAE 2646 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGL- 1245 FD FFGISP EALAMDPQQRLLL+ WEA+E AGIDP +L GS TGVFVG YG Sbjct: 2647 FDAEFFGISPREALAMDPQQRLLLQVGWEAVERAGIDPLSLHGSRTGVFVGAMTQDYGPR 2706 Query: 1246 -----GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRA 1300 + + Y TG +SVASGR++Y LG GPA++VDTACSSSLVALHLA +LR Sbjct: 2707 MHVADASDNVEGYLLTGTTSSVASGRLAYVLGAEGPAVTVDTACSSSLVALHLAGQALRQ 2766 Query: 1301 GECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLS 1360 GEC +ALAGG TV+ATP F+ SRQRGLA DGRCKAFA AADG G +EG GM++L+RLS Sbjct: 2767 GECSMALAGGVTVMATPGTFVEMSRQRGLAVDGRCKAFAAAADGFGPAEGVGMVLLERLS 2826 Query: 1361 DARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHG 1420 DA+R G PVLA++ SAVNQDGASNGLTAP+GP+QQRVI AL+ A ++ ADVDVVEAHG Sbjct: 2827 DAQRLGHPVLAVIRSSAVNQDGASNGLTAPNGPSQQRVIRQALAAADLSSADVDVVEAHG 2886 Query: 1421 TGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQL 1480 TGT LGDPIEAQALLATYG+ T D PLWLGS+KSN+GH+QAAAG+ GVIKMV A+RH + Sbjct: 2887 TGTALGDPIEAQALLATYGQGRTDDRPLWLGSLKSNIGHTQAAAGITGVIKMVMALRHGV 2946 Query: 1481 LPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXX 1540 LPATLH+D+P+ HVDW+ G VQLL++ WP V RPRRA VSSFG+SGTNAH Sbjct: 2947 LPATLHVDEPTPHVDWTAGRVQLLSDQVVWPE-VDRPRRAAVSSFGISGTNAHAILEQAP 3005 Query: 1541 XXXXXXXXXXGPGV------LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLV 1594 V + WVVS R + AQA RL +V E D+G+SLV Sbjct: 3006 EEQTPETDNAAEPVAHDGALVPWVVSGRGEEALRAQAARLHGWVFERPEERLVDIGHSLV 3065 Query: 1595 TTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLG 1654 T+RS F+ R VV+G+ RD LL GLA G G+A GG F+F GQGAQ LG Sbjct: 3066 TSRSAFDDRLVVLGSDRDALLNGLAAAARGEIRPGIARSTERSGGGVAFLFTGQGAQRLG 3125 Query: 1655 MGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGAD----AELLNTTEFAQPALFAV 1710 MGREL +P +D L RPLR+V++ A LL+ T F Q ALFAV Sbjct: 3126 MGRELAECFPVFAVALDEVCAHVDVRLERPLRDVLFAEPGSEAAALLDETAFTQVALFAV 3185 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 EVALYRL+ESW + P ++GHS+G L+AA+VSG RGRLMQALP GG M Sbjct: 3186 EVALYRLVESWSLTPDYLLGHSIGGLAAAYVSGVLSLEDAAEVVVARGRLMQALPKGGAM 3245 Query: 1771 YAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHA 1830 ++QA E E+ LG +VS+AAVNGP +VV+SG +AV+ V + A+GR+V+RL VSHA Sbjct: 3246 VSLQAAEDEVVESLGGRVSIAAVNGPQAVVISGDEDAVTAVAEEWRARGRKVKRLTVSHA 3305 Query: 1831 FHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTG-QLVAEDYGSADYWVRHIREAVRFA 1889 FHSVLMEPML +F V V P IP+IS+ TG L AE S YWV H+R+ V F Sbjct: 3306 FHSVLMEPMLAEFEQVLSRVTLNPPRIPIISDSTGLPLTAEQATSPAYWVGHVRQPVLFH 3365 Query: 1890 DSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXX 1949 +V + G F+E+GP G L+++++ S A + A P LR DR E Sbjct: 3366 QAVTYLADQGVNSFLELGPDGVLSAMVQHS-APDAAQATPLLRSDREETETALTALAELY 3424 Query: 1950 XXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 DW ++ G G R+ LPTYAF H+RFWLA Sbjct: 3425 VNGADVDWTALFEGAG--RIDLPTYAFQHQRFWLA 3457 Score = 686 bits (1769), Expect = 0.0 Identities = 415/975 (42%), Positives = 549/975 (56%), Gaps = 29/975 (2%) Query: 19 IAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKS 78 + TG D + P R+LG S+ + + L+ G+ + A +D+P+ + Sbjct: 2491 VLGHTGTD--RIVAGRPFRELGFDSLTAVELRNRLNTATGLKLSSTAAFDHPTPEVITGH 2548 Query: 79 VLGGDGSQRSADS-DTGCAVLGNGPTN--EPIAVIGMACRFSGQVHGVGPLWDFLAEKKS 135 +L G + +S D A LG+ P + EP+AV+GMACR G + LW L E+ Sbjct: 2549 ILSG--LELGGESPDDEAAALGSVPHSHDEPLAVVGMACRLPGGTNSPERLWQLLMERGD 2606 Query: 136 AITEYPARRLGAAAA--DWLGDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQ 190 I+E P R D D T Y G FL D FD +FF I P EA MDPQQ Sbjct: 2607 VISELPTDRGWDIEGLYDPDPDRPGTSYTRAGGFLYDAAEFDAEFFGISPREALAMDPQQ 2666 Query: 191 RLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTI--WDNTGGSS 248 RLLL+ W A+E AGI P +L S TGVFVG + DY + + + TG +S Sbjct: 2667 RLLLQVGWEAVERAGIDPLSLHGSRTGVFVGAMTQDYGPRMHVADASDNVEGYLLTGTTS 2726 Query: 249 SIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVW 308 S+ + RL+Y L GP++ +DTACSSSLVA HLA ++L GEC +A+ G V+ +P + Sbjct: 2727 SVASGRLAYVLGAEGPAVTVDTACSSSLVALHLAGQALRQGECSMALAGGVTVMATPGTF 2786 Query: 309 RGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQ 368 ++ G C+AF A ADG EG G+V+LERLSDA+R G VLAV+ SAVNQ Sbjct: 2787 VEMSRQRGLAVDGRCKAFAAAADGFGPAEGVGMVLLERLSDAQRLGHPVLAVIRSSAVNQ 2846 Query: 369 DGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGR 428 DG SNG+ APN +Q V+ A AD+ A++D VEAHGTGT++GD IEA AL +G+ Sbjct: 2847 DGASNGLTAPNGPSQQRVIRQALAAADLSSADVDVVEAHGTGTALGDPIEAQALLATYGQ 2906 Query: 429 GRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELG 488 GR +PL +GS+K NIGH + AAGI G+IK V+ L+ G L + + P P++ + Sbjct: 2907 GRTDDRPLWLGSLKSNIGHTQAAAGITGVIKMVMALRHGVLPATLHVDEPTPHVDWTAGR 2966 Query: 489 LAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGV------ 542 + ++ + WP V RPRRA VSSFG GTNAH V Sbjct: 2967 VQLLSDQVVWPE-VDRPRRAAVSSFGISGTNAHAILEQAPEEQTPETDNAAEPVAHDGAL 3025 Query: 543 LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDEL 602 + WVVS R + AQA RL +V E D+G+SLVT+RS F+ R VV+G+ RD L Sbjct: 3026 VPWVVSGRGEEALRAQAARLHGWVFERPEERLVDIGHSLVTSRSAFDDRLVVLGSDRDAL 3085 Query: 603 LAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXX 662 L GLA G G+A GG F+F GQGAQ LGMGREL +P Sbjct: 3086 LNGLAAAARGEIRPGIARSTERSGGGVAFLFTGQGAQRLGMGRELAECFPVFAVALDEVC 3145 Query: 663 XELDRHLARPLREVVWGAD----AELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMG 718 +D L RPLR+V++ A LL+ T F Q ALFAVEVALYRL+ESW + P ++G Sbjct: 3146 AHVDVRLERPLRDVLFAEPGSEAAALLDETAFTQVALFAVEVALYRLVESWSLTPDYLLG 3205 Query: 719 HSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSV 778 HS+G L+AA+VSG RGRLMQALP GG M ++QA E E+ LG +VS+ Sbjct: 3206 HSIGGLAAAYVSGVLSLEDAAEVVVARGRLMQALPKGGAMVSLQAAEDEVVESLGGRVSI 3265 Query: 779 AAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEV 838 AAVNGP +VV+SG +AV+ V + A+GR+V+RL VSHAFHSVLMEPML +F V V Sbjct: 3266 AAVNGPQAVVISGDEDAVTAVAEEWRARGRKVKRLTVSHAFHSVLMEPMLAEFEQVLSRV 3325 Query: 839 YAGRPAIPVISNVTG-QLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPA 897 P IP+IS+ TG L AE S YWV H+R+ V F +V + G F+E+GP Sbjct: 3326 TLNPPRIPIISDSTGLPLTAEQATSPAYWVGHVRQPVLFHQAVTYLADQGVNSFLELGPD 3385 Query: 898 GGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRV 957 G L+++++ S A + A P LR DR E DW ++ G G R+ Sbjct: 3386 GVLSAMVQHS-APDAAQATPLLRSDREETETALTALAELYVNGADVDWTALFEGAG--RI 3442 Query: 958 GLPTYAFAHERFWLA 972 LPTYAF H+RFWLA Sbjct: 3443 DLPTYAFQHQRFWLA 3457 Score = 613 bits (1581), Expect = e-173 Identities = 387/972 (39%), Positives = 536/972 (55%), Gaps = 24/972 (2%) Query: 17 HYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVI 76 H A D +++++ L RDLG SI+ L D G+ +P V+D+P+ V+ Sbjct: 934 HAAAVLGHTDHSDIDVALTFRDLGFDSINATEFRLRLGDAAGLRLPATLVFDHPTPAVVV 993 Query: 77 K----SVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAE 132 +LGG+ ADS + P +EP+A++GMACRF G V LW +AE Sbjct: 994 DFLLTRLLGGE-----ADSLPSTRTAASDP-DEPVAIVGMACRFPGGVSTPEQLWRLVAE 1047 Query: 133 KKSAITEYPARRLGAAAADWLGDEQE--TIY---GCFLEDVEGFDNKFFDIPPDEAALMD 187 A++ P R + + D T Y G FL + FD FF I P EA MD Sbjct: 1048 GVDAVSGLPTDRGWDIESLYHPDPDHPGTSYANEGGFLHEAGEFDAGFFGISPREALAMD 1107 Query: 188 PQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTI--WDNTG 245 PQQRLLL+TSW A+E AGI P +LK S TGVF G + DY L T+ + TG Sbjct: 1108 PQQRLLLQTSWEAVERAGIDPLSLKGSDTGVFTGAMTQDYGPRLHEPDSSGTVDGYMLTG 1167 Query: 246 GSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISP 305 + S+++ R++Y L GP++ +DTACSSSLVA H A ++L GEC +A+ G V+ +P Sbjct: 1168 NAGSVMSGRVAYVLGTEGPAVTVDTACSSSLVALHWAAQALRQGECSMALAGGVTVMATP 1227 Query: 306 EVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSA 365 ++ F ++P G C+AF A ADG EG G+V++ERLSDA+R G +LAV+ SA Sbjct: 1228 GMFVEFSRQRGLAPDGRCKAFAAGADGTGWAEGVGMVLVERLSDAQRLGHPILAVVRSSA 1287 Query: 366 VNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQV 425 VNQDG SNG+ APN +Q V+ A A + A++D VEAHGTGT++GD IEA AL Sbjct: 1288 VNQDGASNGLTAPNGPSQQRVIRQALSTAGLTTADVDAVEAHGTGTNLGDPIEAQALLAT 1347 Query: 426 FGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFA 485 +G+ R +PL++GS+K NIGH + AAG+AG+IK V+ L+ G L + + P+P++ +A Sbjct: 1348 YGQDRPEGRPLLLGSLKSNIGHTQAAAGVAGVIKMVMALRHGVLPATLHVDEPSPHVDWA 1407 Query: 486 ELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLA- 544 + ++ E WP RPRRA VSSFG GTNAH GVL Sbjct: 1408 SGAVELLTEATAWPE-TDRPRRAAVSSFGISGTNAHAILEQAPETDNAAEPVVRDGVLVP 1466 Query: 545 WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLA 604 WVVS R GV AQA L E+V + A D+G+SL+++RSL R VV+G+ R L+ Sbjct: 1467 WVVSGRGVDGVRAQAAGLREWVLEHPQHSATDIGFSLLSSRSLHRDRLVVLGSDRQVLVD 1526 Query: 605 GLAEVVEGRPGVG-VASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXX 663 GLA EG P G V S + + VFVFPGQG+QW+GMGREL A P Sbjct: 1527 GLAAAAEGAPWPGLVQSSGDVSLSRAVFVFPGQGSQWVGMGRELYASSPVFRARLDECAR 1586 Query: 664 ELDRHLARPLREVVWG-ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVG 722 LD + L +VV G + A L + QP L+AV V+L + ESWG+ P V+GHS G Sbjct: 1587 ALDPLVDWSLIDVVRGESGAPGLERVDVVQPVLWAVMVSLAAVWESWGVVPAAVVGHSQG 1646 Query: 723 ELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVN 782 E++AA V+G +R R ++A+ G G M +V E L G+ VS+AAVN Sbjct: 1647 EIAAACVAGALSVEDAAQVVALRSRAVRAMAGDGAMVSVALPAAEAEALTGDGVSLAAVN 1706 Query: 783 GPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGR 842 GP SVVLSG R A++ VV+ L AQG R + + V +A HS ME + ++ + + Sbjct: 1707 GPSSVVLSGDRSALTPVVEGLTAQGVRTKWVPVDYASHSAHMERIRDELLEILSGIEPKT 1766 Query: 843 PAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTS 902 IP+ S V+ + A YW +IR VRF ++V + G T FVEV P L Sbjct: 1767 SRIPLYSTVSAARIDTSRMDASYWFDNIRGTVRFHETVQALIADGLTAFVEVSPHPVLAM 1826 Query: 903 LIEESL--AQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDW-ASVLAGCGGQRVGL 959 ++++L A+ + +++ TLR+D+ E DW + A +RV L Sbjct: 1827 SVQDTLDQAEATGLSIGTLRRDQNEHETLLTAAAELFVAGLPIDWHTAAFADLDTRRVDL 1886 Query: 960 PTYAFAHERFWL 971 PTYAF ERFWL Sbjct: 1887 PTYAFQTERFWL 1898 Score = 575 bits (1481), Expect = e-161 Identities = 378/1012 (37%), Positives = 524/1012 (51%), Gaps = 39/1012 (3%) Query: 1118 IAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRH 1177 IA+VGM CR PG + + W L+ S G +G DR ++ +P R Sbjct: 7 IAVVGMSCRLPGALDL-GEFWDLLMSSGSGVGLPGSDRSRRLDDSHEP----------RR 55 Query: 1178 GGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVG 1237 G++ V FD FFG+ P EA AMDP+QRL+LE SWEALE+AGI P L GSS GVF+G Sbjct: 56 AGYLQQVDLFDASFFGLGPQEATAMDPRQRLILELSWEALENAGISPAGLAGSSVGVFLG 115 Query: 1238 IYGDGY-GLGT-SQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAA 1295 GD Y G GT + A Y G +V + R+S+ L L GP++ VDTA SSSLVA+H+A Sbjct: 116 ASGDDYPGAGTVADANPYLAAGTNRAVIANRVSHALDLTGPSLLVDTAQSSSLVAVHMAC 175 Query: 1296 NSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLV 1355 S+R GEC A+ GG + + ++ DG C F A+G EG G+LV Sbjct: 176 ESIRRGECTTAIVGGVNLNLSSRRIHMLESLGVVSPDGECFTFDARANGFVPGEGGGVLV 235 Query: 1356 LQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDV 1415 L+ LS A G V A++ G+A+N DGA+ GL++PS AQ+ VI A A + DV Sbjct: 236 LKDLSAALADGGQVHAVIRGTALNHDGATFGLSSPSPAAQEAVIRQAHRAADVLPGDVRF 295 Query: 1416 VEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEA 1475 VE HGTGT+ GD EA AL A + D ++PL +GS+K+N+GH AA+G G+IK V + Sbjct: 296 VELHGTGTQAGDATEATALGAAFAGDSPRESPLLVGSVKTNIGHLDAASGAVGLIKAVLS 355 Query: 1476 MRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGR-PRRAGVSSFGVSGTNAHX 1534 + ++ LP + + +P+ +D +++ T R+ G P +AGVSSFG+ G N H Sbjct: 356 LTNRKLPPSRNFAEPNPAIDLPALGLEVATSVRDLAGDSGESPVQAGVSSFGMGGANCHV 415 Query: 1535 XXXXXXXXXXXXXXXX-----------GPGVLA-WVVSARTAAGVGAQAGRLLEFVRAGR 1582 GVL WVVS R GV AQA RL E+V Sbjct: 416 VVSDALDLDTSAPRPSTETASDTPPETSDGVLVPWVVSGRGVDGVRAQAARLREWVLERS 475 Query: 1583 ELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA--SGVAMPGGK 1640 DVG+SL+++RSL R VV+G+ R L+ GLA VEG P GV SG + + Sbjct: 476 ADRPVDVGFSLLSSRSLHRDRLVVLGSDRQVLVDGLAAFVEGAPWPGVVGGSGGGVVADR 535 Query: 1641 TVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVV-WGADAELLNT 1699 VFVFPGQG+QW+GMGREL A P LD + L +VV G+ A L Sbjct: 536 AVFVFPGQGSQWVGMGRELYASSPVFRARLDECAAALDPLVDWSLIDVVRGGSGAPGLER 595 Query: 1700 TEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGR 1759 + QP L+AV V+L + ESWG+ P V+GHS GE++AA V+G +R R Sbjct: 596 VDVVQPVLWAVMVSLAAVWESWGVVPAAVVGHSQGEIAAACVAGALSVVDAARVVALRSR 655 Query: 1760 LMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQG 1819 ++A+ G G M +V E L G+ VS+AAVNGP SVVLSG R A++ VV+RL+A+G Sbjct: 656 ALRAMAGDGAMVSVALPVAEAEALTGDGVSLAAVNGPSSVVLSGDRSALTPVVERLSAEG 715 Query: 1820 RRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWV 1879 R + + V +A HS ME + ++ + + IP+ S V+ +++ A YW Sbjct: 716 VRTKWVPVDYASHSAHMERIHDELLEILSGIVPKTSRIPLYSTVSAEVIDTSVMDAGYWF 775 Query: 1880 RHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL--AQVSVVAVPTLRKDRPE 1937 +IR VRF ++V + G T FVE+ P L ++++L A+ + +++ TLR+D E Sbjct: 776 DNIRGTVRFHETVQALIADGLTAFVEISPHPVLAMSVQDTLDQAEATGLSIGTLRRDENE 835 Query: 1938 PFXXXXXXXXXXXXXXXXDW-ASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXX 1996 DW + A ++V LPTYAF +WL Sbjct: 836 EKSLLTAAAELFVAGLPIDWNTAAFADLDTRQVDLPTYAFQRRPYWLET-------VAQT 888 Query: 1997 XXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLD 2056 + R+ GL + AV V H AAVLG + +D Sbjct: 889 VRVGAPAAAPTESPEVPGSRSPLAERVAGLPQGARHQAVTDFVRAHAAAVLGHTDHSDID 948 Query: 2057 AGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHL 2108 F D G S++A E R RL G+ L AT FD+PTP + D LL+ L Sbjct: 949 VALTFRDLGFDSINATEFRLRLGDAAGLRLPATLVFDHPTPAVVVDFLLTRL 1000 Score = 83.2 bits (204), Expect = 4e-13 Identities = 47/99 (47%), Positives = 59/99 (59%), Gaps = 5/99 (5%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 +L GLSD EQ VL +V A+V+G ++ A +AF D G SL+AVELRNRL Sbjct: 4031 QLAGLSDTEQYKTVLELVRVQAASVVGHLTPERITAERAFRDVGFDSLTAVELRNRLNNA 4090 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPEL 2120 TG+ L TT FD+PTP LA+HL L T TPE+ Sbjct: 4091 TGLVLPTTTIFDHPTPVLLAEHLQREL-----TSTTPEI 4124 Score = 80.9 bits (198), Expect = 2e-12 Identities = 42/87 (48%), Positives = 56/87 (64%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL S E++ +L +V AAVLG G ++ AG+ F + G SL+AVELRNRL T Sbjct: 2467 RLADRSPVERRKTILELVRAQAAAVLGHTGTDRIVAGRPFRELGFDSLTAVELRNRLNTA 2526 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ LS+T AFD+PTP + H+LS L Sbjct: 2527 TGLKLSSTAAFDHPTPEVITGHILSGL 2553 Score = 80.1 bits (196), Expect = 4e-12 Identities = 43/87 (49%), Positives = 54/87 (62%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 +L GLSD EQ VL +V A+V+G ++ A +AF D G SL+AVELRNRL Sbjct: 4031 QLAGLSDTEQYKTVLELVRVQAASVVGHLTPERITAERAFRDVGFDSLTAVELRNRLNNA 4090 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL 1096 TG+ L TT FD+PTP LA+HL L Sbjct: 4091 TGLVLPTTTIFDHPTPVLLAEHLQREL 4117 >tr|Q7D9V6|Q7D9V6_MYCTU Tax_Id=1773 SubName: Full=Polyketide synthase;[Mycobacterium tuberculosis] Length = 1402 Score = 1345 bits (3481), Expect = 0.0 Identities = 719/1155 (62%), Positives = 821/1155 (71%), Gaps = 35/1155 (3%) Query: 1 VTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC 60 +TDG +AD LQ+WF Y++ C EV+LD+P+RDLGL SIDVLAIPG+L D G C Sbjct: 1 MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSIDVLAIPGDLGDRFGFC 60 Query: 61 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADS---DTGCA---VLGNGPTNEPIAVIGMAC 114 +PDLAVWDNPSA+D+I S+L +QRSADS G A G G NEP+AVIG+ C Sbjct: 61 IPDLAVWDNPSANDLIDSLL----NQRSADSLRESHGHADRNTQGRGSINEPVAVIGVGC 116 Query: 115 RFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNK 174 RF G + G LWDFL EKK AIT YP R A G E+ G FL+DV GFDN+ Sbjct: 117 RFPGDIDGPERLWDFLTEKKCAITAYPDRGFTNA-----GTFAES--GGFLKDVAGFDNR 169 Query: 175 FFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPG 234 FFDIPPDEA MDPQQRLLLE SW ALEHAGI+P++L+LS TGVFVGVSSTDYVRL+ Sbjct: 170 FFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSRTGVFVGVSSTDYVRLVSAS 229 Query: 235 GR-KPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDL 293 + K TIWDNTGGSSSIIANR+SYFLD+ GPS+VIDTACSSSLVA HLA +SL++ +CD+ Sbjct: 230 AQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVHLACRSLSTWDCDI 289 Query: 294 AVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRA 353 A+V GTNVLISPE W GF+EAG++S TG C AFD ADGMVRGEGCGV+VL+RLSDAR Sbjct: 290 ALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEGCGVIVLQRLSDARLE 349 Query: 354 GRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSV 413 GR +LA+LTGSAVNQDG+SNGIMAPNP AQI VL++ACK A +DP EI YVEAHGTGTS+ Sbjct: 350 GRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENACKSARVDPLEIGYVEAHGTGTSL 409 Query: 414 GDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSG 473 GDRIEAHALG VFGR R + PLMIGSIKPNIGHLEGAAGIAGLIK VLM++RG LLPSG Sbjct: 410 GDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLEGAAGIAGLIKAVLMVERGSLLPSG 469 Query: 474 AFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXX 533 F PNP IPF ELGL VV+E QEWP V GRPRRAGVSSFGFGGTNAH Sbjct: 470 GFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAGVSSFGFGGTNAHVIVEEAGSVGAD 529 Query: 534 XXXXX------GPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 587 G GV+AWV+S +TA+ + AQAGRL +VRA LD DVGYSLV+TRS+ Sbjct: 530 TVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLGRYVRARPALDVVDVGYSLVSTRSV 589 Query: 588 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 647 F+HRAVVVG RDELLAGLA VV GRP GV GV P GKT FVF GQG+QWLGMG EL Sbjct: 590 FDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSEL 649 Query: 648 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 707 A YP ELDRHL PLR+V+WG D +LLNTTEFAQPALFAVEVALYRLL Sbjct: 650 YAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQDLLNTTEFAQPALFAVEVALYRLLM 709 Query: 708 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 767 SWG+RPGLV+GHSVGEL+AAHV+G RGRLMQALP GG M+AVQA E E Sbjct: 710 SWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDE 769 Query: 768 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 827 + P+LG VS+AAVNGP SVV+SGA +AVS + DRL QGRRV RLAVSHAFHS LMEPM Sbjct: 770 VAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPM 829 Query: 828 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 887 + +F AVA E+ G P IPVISNVTGQLVA+D+ SADYW RHIR VRF DSV AH AG Sbjct: 830 IAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASADYWARHIRAVVRFGDSVRSAHCAG 889 Query: 888 ATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWAS 947 A+RF+EVGP GGLTSLIE SLA +V+VPTLRKDRPEP DWAS Sbjct: 890 ASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDRPEPVSVMTAAAQGFVSGMGLDWAS 949 Query: 948 VLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXX 1007 V +G +RV LPTYAF H++FWLA Sbjct: 950 VFSGYRPKRVELPTYAFQHQKFWLA------PAPSVSDPTAAGQIGASDGGAELLASSGF 1003 Query: 1008 XXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLK 1067 RL G S EQ AA + +VCEH AAVLGRDGAA LDAGQAF+D+G SLSAVELRNRL Sbjct: 1004 AARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSGFNSLSAVELRNRLT 1063 Query: 1068 TLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 +T VTL AT FD+PTPT+LA +L++ + SA AAA RID + C Sbjct: 1064 AVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA-AAAANPAERIDALTDVFLQAC-- 1120 Query: 1128 PGGVSSPAQLWQLVA 1142 A W++VA Sbjct: 1121 --DAGRDADGWKMVA 1133 Score = 1325 bits (3428), Expect = 0.0 Identities = 728/1379 (52%), Positives = 889/1379 (64%), Gaps = 35/1379 (2%) Query: 1051 DAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQN-RSAPAAAVR 1109 D GL S+ + + L G + +D P+ L D LL+ + R + A R Sbjct: 38 DLGLKSIDVLAIPGDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESHGHADR 97 Query: 1110 T---RVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPD 1166 R I+EP+A++G+GCR+PG + P +LW + I +P DRG+ Sbjct: 98 NTQGRGSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAITAYP-DRGF--------- 147 Query: 1167 PDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQA 1226 T+ GGF+ DVA FD FF I P EAL MDPQQRLLLE SWEALE AGI P++ Sbjct: 148 --TNAGTFAESGGFLKDVAGFDNRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPES 205 Query: 1227 LRGSSTGVFVGIYGDGY-GLGTSQAQW----YADTGHITSVASGRISYCLGLAGPAISVD 1281 LR S TGVFVG+ Y L ++ AQ + +TG +S+ + RISY L + GP+I +D Sbjct: 206 LRLSRTGVFVGVSSTDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVID 265 Query: 1282 TACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADA 1341 TACSSSLVA+HLA SL +CD+AL GG+ VL +P + GF L+ G C AF + Sbjct: 266 TACSSSLVAVHLACRSLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKS 325 Query: 1342 ADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISA 1401 ADG EG G++VLQRLSDAR G+ +LAIL GSAVNQDG SNG+ AP+ AQ V+ Sbjct: 326 ADGMVRGEGCGVIVLQRLSDARLEGRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLEN 385 Query: 1402 ALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQ 1461 A A + ++ VEAHGTGT LGD IEA AL +GR PL +GSIK N+GH + Sbjct: 386 ACKSARVDPLEIGYVEAHGTGTSLGDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLE 445 Query: 1462 AAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAG 1521 AAG+AG+IK V + L + +P+ + ++ ++++ E +EWP V GRPRRAG Sbjct: 446 GAAGIAGLIKAVLMVERGSLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAG 505 Query: 1522 VSSFGVSGTNAHXXXXXXXXXXXXXXXXX------GPGVLAWVVSARTAAGVGAQAGRLL 1575 VSSFG GTNAH G GV+AWV+S +TA+ + AQAGRL Sbjct: 506 VSSFGFGGTNAHVIVEEAGSVGADTVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLG 565 Query: 1576 EFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVA 1635 +VRA LD DVGYSLV+TRS+F+HRAVVVG RDELLAGLA VV GRP GV GV Sbjct: 566 RYVRARPALDVVDVGYSLVSTRSVFDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVG 625 Query: 1636 MPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAE 1695 P GKT FVF GQG+QWLGMG EL A YP ELDRHL PLR+V+WG D + Sbjct: 626 KPAGKTAFVFAGQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQD 685 Query: 1696 LLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXX 1755 LLNTTEFAQPALFAVEVALYRLL SWG+RPGLV+GHSVGEL+AAHV+G Sbjct: 686 LLNTTEFAQPALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVA 745 Query: 1756 MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRL 1815 RGRLMQALP GG M+AVQA E E+ P+LG VS+AAVNGP SVV+SGA +AVS + DRL Sbjct: 746 ARGRLMQALPAGGAMFAVQAREDEVAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRL 805 Query: 1816 AAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSA 1875 QGRRV RLAVSHAFHS LMEPM+ +F AVA E+ G P IPVISNVTGQLVA+D+ SA Sbjct: 806 RGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASA 865 Query: 1876 DYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDR 1935 DYW RHIR VRF DSV AH AGA+RF+EVGP GGLTSLIE SLA +V+VPTLRKDR Sbjct: 866 DYWARHIRAVVRFGDSVRSAHCAGASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDR 925 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXX 1995 PEP DWASV +G +RV LPTYAF H++FWLA Sbjct: 926 PEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLA------PAPSV 979 Query: 1996 XXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQL 2055 RL G S EQ AA + +VCEH AAVLGRDGAA L Sbjct: 980 SDPTAAGQIGASDGGAELLASSGFAARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGL 1039 Query: 2056 DAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHL--HHQNP 2113 DAGQAF+D+G SLSAVELRNRL +T VTL AT FD+PTPT+LA +L++ + H + Sbjct: 1040 DAGQAFADSGFNSLSAVELRNRLTAVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA 1099 Query: 2114 TGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAG 2173 A +R+DALTD+FLQ CDAGRD DGW++VALA+N RERM++PV K V LLA Sbjct: 1100 AAAANPAERIDALTDVFLQACDAGRDADGWKMVALASNTRERMSSPVRNNVSKNVALLAD 1159 Query: 2174 GRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGA 2233 G SDV V+C+PTLTVLS Y D+A AM GRHSV++L+LPGFD DALPQ+ ++++E Sbjct: 1160 GISDVVVICIPTLTVLSDQREYRDIANAMTGRHSVYSLTLPGFDSSDALPQNADMIVETV 1219 Query: 2234 AQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVNADN 2293 + AI+ VG VL+GYSSGGVLA+AL S+L+ +HQR PLGVALIDTYLPSQI N Sbjct: 1220 SNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNPLGVALIDTYLPSQIANPSM 1279 Query: 2294 PDQVGVNETGALFSRRVTSMARELDQLNXXXXXXXXXXXXXFGTWEPVVSAVPLLNMIAM 2353 + N+TG SR V +AR L++L F WEP S P+LN++A Sbjct: 1280 NEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRSMAPVLNIVAK 1339 Query: 2354 DETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATTTALHGWISGLIR 2412 D A E +R ERINRWR A AEA+YSV EVPGDHF M++TSS+A T +H WISGL+R Sbjct: 1340 DRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWISGLVR 1398 >tr|O86335|O86335_MYCTU Tax_Id=1773 (pks6)SubName: Full=PROBABLE MEMBRANE BOUND POLYKETIDE SYNTHASE PKS6;[Mycobacterium tuberculosis] Length = 1402 Score = 1345 bits (3480), Expect = 0.0 Identities = 719/1155 (62%), Positives = 821/1155 (71%), Gaps = 35/1155 (3%) Query: 1 VTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC 60 +TDG +AD LQ+WF Y++ C EV+LD+P+RDLGL SIDVLAIPG+L D G C Sbjct: 1 MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSIDVLAIPGDLGDRFGFC 60 Query: 61 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADS---DTGCA---VLGNGPTNEPIAVIGMAC 114 +PDLAVWDNPSA+D+I S+L +QRSADS G A G G NEP+AVIG+ C Sbjct: 61 IPDLAVWDNPSANDLIDSLL----NQRSADSLRESHGHADRNTQGRGSINEPVAVIGVGC 116 Query: 115 RFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNK 174 RF G + G LWDFL EKK AIT YP R A G E+ G FL+DV GFDN+ Sbjct: 117 RFPGDIDGPERLWDFLTEKKCAITAYPDRGFTNA-----GTFAES--GGFLKDVAGFDNR 169 Query: 175 FFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPG 234 FFDIPPDEA MDPQQRLLLE SW ALEHAGI+P++L+LS TGVFVGVSSTDYVRL+ Sbjct: 170 FFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSRTGVFVGVSSTDYVRLVSAS 229 Query: 235 GR-KPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDL 293 + K TIWDNTGGSSSIIANR+SYFLD+ GPS+VIDTACSSSLVA HLA +SL++ +CD+ Sbjct: 230 AQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVHLACRSLSTWDCDI 289 Query: 294 AVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRA 353 A+V GTNVLISPE W GF+EAG++S TG C AFD ADGMVRGEGCGV+VL+RLSDAR Sbjct: 290 ALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEGCGVIVLQRLSDARLE 349 Query: 354 GRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSV 413 GR +LA+LTGSAVNQDG+SNGIMAPNP AQI VL++ACK A +DP EI YVEAHGTGTS+ Sbjct: 350 GRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENACKSARVDPLEIGYVEAHGTGTSL 409 Query: 414 GDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSG 473 GDRIEAHALG VFGR R + PLMIGSIKPNIGHLEGAAGIAGLIK VLM++RG LLPSG Sbjct: 410 GDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLEGAAGIAGLIKAVLMVERGSLLPSG 469 Query: 474 AFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXX 533 F PNP IPF ELGL VV+E QEWP V GRPRRAGVSSFGFGGTNAH Sbjct: 470 GFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAGVSSFGFGGTNAHVIVEEAGSVGAD 529 Query: 534 XXXXX------GPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 587 G GV+AWV+S +TA+ + AQAGRL +VRA LD DVGYSLV+TRS+ Sbjct: 530 TVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLGRYVRARPALDVVDVGYSLVSTRSV 589 Query: 588 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 647 F+HRAVVVG RDELLAGLA VV GRP GV GV P GKT FVF GQG+QWLGMG EL Sbjct: 590 FDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSEL 649 Query: 648 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 707 A YP ELDRHL PLR+V+WG D +LLNTTEFAQPALFAVEVALYRLL Sbjct: 650 YAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQDLLNTTEFAQPALFAVEVALYRLLM 709 Query: 708 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 767 SWG+RPGLV+GHSVGEL+AAHV+G RGRLMQALP GG M+AVQA E E Sbjct: 710 SWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDE 769 Query: 768 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 827 + P+LG VS+AAVNGP SVV+SGA +AVS + DRL QGRRV RLAVSHAFHS LMEPM Sbjct: 770 VAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPM 829 Query: 828 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 887 + +F AVA E+ G P IPVISNVTGQLVA+D+ SADYW RHIR VRF DSV AH AG Sbjct: 830 IAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASADYWARHIRAVVRFGDSVRSAHCAG 889 Query: 888 ATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWAS 947 A+RF+EVGP GGLTSLIE SLA +V+VPTLRKDRPEP DWAS Sbjct: 890 ASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDRPEPVSVMTAAAQGFVSGMGLDWAS 949 Query: 948 VLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXX 1007 V +G +RV LPTYAF H++FWLA Sbjct: 950 VFSGYRPKRVELPTYAFQHQKFWLA------PAPSVSDPTAAGQIGASDGGAELLASSGF 1003 Query: 1008 XXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLK 1067 RL G S EQ AA + +VCEH AAVLGRDGAA LDAGQAF+D+G SLSAVELRNRL Sbjct: 1004 AARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSGFNSLSAVELRNRLT 1063 Query: 1068 TLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 +T VTL AT FD+PTPT+LA +L++ + SA AAA RID + C Sbjct: 1064 AVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA-AAAANPAERIDALTDLFLQAC-- 1120 Query: 1128 PGGVSSPAQLWQLVA 1142 A W++VA Sbjct: 1121 --DAGRDADGWKMVA 1133 Score = 1326 bits (3431), Expect = 0.0 Identities = 729/1379 (52%), Positives = 889/1379 (64%), Gaps = 35/1379 (2%) Query: 1051 DAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQN-RSAPAAAVR 1109 D GL S+ + + L G + +D P+ L D LL+ + R + A R Sbjct: 38 DLGLKSIDVLAIPGDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESHGHADR 97 Query: 1110 T---RVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPD 1166 R I+EP+A++G+GCR+PG + P +LW + I +P DRG+ Sbjct: 98 NTQGRGSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAITAYP-DRGF--------- 147 Query: 1167 PDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQA 1226 T+ GGF+ DVA FD FF I P EAL MDPQQRLLLE SWEALE AGI P++ Sbjct: 148 --TNAGTFAESGGFLKDVAGFDNRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPES 205 Query: 1227 LRGSSTGVFVGIYGDGY-GLGTSQAQW----YADTGHITSVASGRISYCLGLAGPAISVD 1281 LR S TGVFVG+ Y L ++ AQ + +TG +S+ + RISY L + GP+I +D Sbjct: 206 LRLSRTGVFVGVSSTDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVID 265 Query: 1282 TACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADA 1341 TACSSSLVA+HLA SL +CD+AL GG+ VL +P + GF L+ G C AF + Sbjct: 266 TACSSSLVAVHLACRSLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKS 325 Query: 1342 ADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISA 1401 ADG EG G++VLQRLSDAR G+ +LAIL GSAVNQDG SNG+ AP+ AQ V+ Sbjct: 326 ADGMVRGEGCGVIVLQRLSDARLEGRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLEN 385 Query: 1402 ALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQ 1461 A A + ++ VEAHGTGT LGD IEA AL +GR PL +GSIK N+GH + Sbjct: 386 ACKSARVDPLEIGYVEAHGTGTSLGDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLE 445 Query: 1462 AAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAG 1521 AAG+AG+IK V + L + +P+ + ++ ++++ E +EWP V GRPRRAG Sbjct: 446 GAAGIAGLIKAVLMVERGSLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAG 505 Query: 1522 VSSFGVSGTNAHXXXXXXXXXXXXXXXXX------GPGVLAWVVSARTAAGVGAQAGRLL 1575 VSSFG GTNAH G GV+AWV+S +TA+ + AQAGRL Sbjct: 506 VSSFGFGGTNAHVIVEEAGSVGADTVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLG 565 Query: 1576 EFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVA 1635 +VRA LD DVGYSLV+TRS+F+HRAVVVG RDELLAGLA VV GRP GV GV Sbjct: 566 RYVRARPALDVVDVGYSLVSTRSVFDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVG 625 Query: 1636 MPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAE 1695 P GKT FVF GQG+QWLGMG EL A YP ELDRHL PLR+V+WG D + Sbjct: 626 KPAGKTAFVFAGQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQD 685 Query: 1696 LLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXX 1755 LLNTTEFAQPALFAVEVALYRLL SWG+RPGLV+GHSVGEL+AAHV+G Sbjct: 686 LLNTTEFAQPALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVA 745 Query: 1756 MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRL 1815 RGRLMQALP GG M+AVQA E E+ P+LG VS+AAVNGP SVV+SGA +AVS + DRL Sbjct: 746 ARGRLMQALPAGGAMFAVQAREDEVAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRL 805 Query: 1816 AAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSA 1875 QGRRV RLAVSHAFHS LMEPM+ +F AVA E+ G P IPVISNVTGQLVA+D+ SA Sbjct: 806 RGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASA 865 Query: 1876 DYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDR 1935 DYW RHIR VRF DSV AH AGA+RF+EVGP GGLTSLIE SLA +V+VPTLRKDR Sbjct: 866 DYWARHIRAVVRFGDSVRSAHCAGASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDR 925 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXX 1995 PEP DWASV +G +RV LPTYAF H++FWLA Sbjct: 926 PEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLA------PAPSV 979 Query: 1996 XXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQL 2055 RL G S EQ AA + +VCEH AAVLGRDGAA L Sbjct: 980 SDPTAAGQIGASDGGAELLASSGFAARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGL 1039 Query: 2056 DAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHL--HHQNP 2113 DAGQAF+D+G SLSAVELRNRL +T VTL AT FD+PTPT+LA +L++ + H + Sbjct: 1040 DAGQAFADSGFNSLSAVELRNRLTAVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA 1099 Query: 2114 TGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAG 2173 A +R+DALTDLFLQ CDAGRD DGW++VALA+N RERM++PV K V LLA Sbjct: 1100 AAAANPAERIDALTDLFLQACDAGRDADGWKMVALASNTRERMSSPVRNNVSKNVALLAD 1159 Query: 2174 GRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGA 2233 G SDV V+C+PTLTVLS Y D+A AM GRHSV++L+LPGFD DALPQ+ ++++E Sbjct: 1160 GISDVVVICIPTLTVLSDQREYRDIANAMTGRHSVYSLTLPGFDSSDALPQNADMIVETV 1219 Query: 2234 AQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVNADN 2293 + AI+ VG VL+GYSSGGVLA+AL S+L+ +HQR PLGVALIDTYLPSQI N Sbjct: 1220 SNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNPLGVALIDTYLPSQIANPSM 1279 Query: 2294 PDQVGVNETGALFSRRVTSMARELDQLNXXXXXXXXXXXXXFGTWEPVVSAVPLLNMIAM 2353 + N+TG SR V +AR L++L F WEP S P+LN++A Sbjct: 1280 NEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRSMAPVLNIVAK 1339 Query: 2354 DETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATTTALHGWISGLIR 2412 D A E +R ERINRWR A AEA+YSV EVPGDHF M++TSS+A T +H WISGL+R Sbjct: 1340 DRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWISGLVR 1398 >tr|C6DSJ5|C6DSJ5_MYCTK Tax_Id=478434 SubName: Full=Membrane bound polyketide synthase pks6;[Mycobacterium tuberculosis] Length = 1402 Score = 1345 bits (3480), Expect = 0.0 Identities = 719/1155 (62%), Positives = 821/1155 (71%), Gaps = 35/1155 (3%) Query: 1 VTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC 60 +TDG +AD LQ+WF Y++ C EV+LD+P+RDLGL SIDVLAIPG+L D G C Sbjct: 1 MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSIDVLAIPGDLGDRFGFC 60 Query: 61 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADS---DTGCA---VLGNGPTNEPIAVIGMAC 114 +PDLAVWDNPSA+D+I S+L +QRSADS G A G G NEP+AVIG+ C Sbjct: 61 IPDLAVWDNPSANDLIDSLL----NQRSADSLRESHGHADRNTQGRGSINEPVAVIGVGC 116 Query: 115 RFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNK 174 RF G + G LWDFL EKK AIT YP R A G E+ G FL+DV GFDN+ Sbjct: 117 RFPGDIDGPERLWDFLTEKKCAITAYPDRGFTNA-----GTFAES--GGFLKDVAGFDNR 169 Query: 175 FFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPG 234 FFDIPPDEA MDPQQRLLLE SW ALEHAGI+P++L+LS TGVFVGVSSTDYVRL+ Sbjct: 170 FFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSRTGVFVGVSSTDYVRLVSAS 229 Query: 235 GR-KPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDL 293 + K TIWDNTGGSSSIIANR+SYFLD+ GPS+VIDTACSSSLVA HLA +SL++ +CD+ Sbjct: 230 AQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVHLACRSLSTWDCDI 289 Query: 294 AVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRA 353 A+V GTNVLISPE W GF+EAG++S TG C AFD ADGMVRGEGCGV+VL+RLSDAR Sbjct: 290 ALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEGCGVIVLQRLSDARLE 349 Query: 354 GRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSV 413 GR +LA+LTGSAVNQDG+SNGIMAPNP AQI VL++ACK A +DP EI YVEAHGTGTS+ Sbjct: 350 GRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENACKSARVDPLEIGYVEAHGTGTSL 409 Query: 414 GDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSG 473 GDRIEAHALG VFGR R + PLMIGSIKPNIGHLEGAAGIAGLIK VLM++RG LLPSG Sbjct: 410 GDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLEGAAGIAGLIKAVLMVERGSLLPSG 469 Query: 474 AFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXX 533 F PNP IPF ELGL VV+E QEWP V GRPRRAGVSSFGFGGTNAH Sbjct: 470 GFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAGVSSFGFGGTNAHVIVEEAGSVGAD 529 Query: 534 XXXXX------GPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 587 G GV+AWV+S +TA+ + AQAGRL +VRA LD DVGYSLV+TRS+ Sbjct: 530 TVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLGRYVRARPALDVVDVGYSLVSTRSV 589 Query: 588 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 647 F+HRAVVVG RDELLAGLA VV GRP GV GV P GKT FVF GQG+QWLGMG EL Sbjct: 590 FDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSEL 649 Query: 648 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 707 A YP ELDRHL PLR+V+WG D +LLNTTEFAQPALFAVEVALYRLL Sbjct: 650 YAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQDLLNTTEFAQPALFAVEVALYRLLM 709 Query: 708 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 767 SWG+RPGLV+GHSVGEL+AAHV+G RGRLMQALP GG M+AVQA E E Sbjct: 710 SWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDE 769 Query: 768 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 827 + P+LG VS+AAVNGP SVV+SGA +AVS + DRL QGRRV RLAVSHAFHS LMEPM Sbjct: 770 VAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPM 829 Query: 828 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 887 + +F AVA E+ G P IPVISNVTGQLVA+D+ SADYW RHIR VRF DSV AH AG Sbjct: 830 IAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASADYWARHIRAVVRFGDSVRSAHCAG 889 Query: 888 ATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWAS 947 A+RF+EVGP GGLTSLIE SLA +V+VPTLRKDRPEP DWAS Sbjct: 890 ASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDRPEPVSVMTAAAQGFVSGMGLDWAS 949 Query: 948 VLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXX 1007 V +G +RV LPTYAF H++FWLA Sbjct: 950 VFSGYRPKRVELPTYAFQHQKFWLA------PAPSVSDPTAAGQIGASDGGAELLASSGF 1003 Query: 1008 XXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLK 1067 RL G S EQ AA + +VCEH AAVLGRDGAA LDAGQAF+D+G SLSAVELRNRL Sbjct: 1004 AARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSGFNSLSAVELRNRLT 1063 Query: 1068 TLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 +T VTL AT FD+PTPT+LA +L++ + SA AAA RID + C Sbjct: 1064 AVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA-AAAANPAERIDALTDLFLQAC-- 1120 Query: 1128 PGGVSSPAQLWQLVA 1142 A W++VA Sbjct: 1121 --DAGRDADGWKMVA 1133 Score = 1326 bits (3431), Expect = 0.0 Identities = 729/1379 (52%), Positives = 889/1379 (64%), Gaps = 35/1379 (2%) Query: 1051 DAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQN-RSAPAAAVR 1109 D GL S+ + + L G + +D P+ L D LL+ + R + A R Sbjct: 38 DLGLKSIDVLAIPGDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESHGHADR 97 Query: 1110 T---RVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPD 1166 R I+EP+A++G+GCR+PG + P +LW + I +P DRG+ Sbjct: 98 NTQGRGSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAITAYP-DRGF--------- 147 Query: 1167 PDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQA 1226 T+ GGF+ DVA FD FF I P EAL MDPQQRLLLE SWEALE AGI P++ Sbjct: 148 --TNAGTFAESGGFLKDVAGFDNRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPES 205 Query: 1227 LRGSSTGVFVGIYGDGY-GLGTSQAQW----YADTGHITSVASGRISYCLGLAGPAISVD 1281 LR S TGVFVG+ Y L ++ AQ + +TG +S+ + RISY L + GP+I +D Sbjct: 206 LRLSRTGVFVGVSSTDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVID 265 Query: 1282 TACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADA 1341 TACSSSLVA+HLA SL +CD+AL GG+ VL +P + GF L+ G C AF + Sbjct: 266 TACSSSLVAVHLACRSLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKS 325 Query: 1342 ADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISA 1401 ADG EG G++VLQRLSDAR G+ +LAIL GSAVNQDG SNG+ AP+ AQ V+ Sbjct: 326 ADGMVRGEGCGVIVLQRLSDARLEGRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLEN 385 Query: 1402 ALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQ 1461 A A + ++ VEAHGTGT LGD IEA AL +GR PL +GSIK N+GH + Sbjct: 386 ACKSARVDPLEIGYVEAHGTGTSLGDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLE 445 Query: 1462 AAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAG 1521 AAG+AG+IK V + L + +P+ + ++ ++++ E +EWP V GRPRRAG Sbjct: 446 GAAGIAGLIKAVLMVERGSLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAG 505 Query: 1522 VSSFGVSGTNAHXXXXXXXXXXXXXXXXX------GPGVLAWVVSARTAAGVGAQAGRLL 1575 VSSFG GTNAH G GV+AWV+S +TA+ + AQAGRL Sbjct: 506 VSSFGFGGTNAHVIVEEAGSVGADTVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLG 565 Query: 1576 EFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVA 1635 +VRA LD DVGYSLV+TRS+F+HRAVVVG RDELLAGLA VV GRP GV GV Sbjct: 566 RYVRARPALDVVDVGYSLVSTRSVFDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVG 625 Query: 1636 MPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAE 1695 P GKT FVF GQG+QWLGMG EL A YP ELDRHL PLR+V+WG D + Sbjct: 626 KPAGKTAFVFAGQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQD 685 Query: 1696 LLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXX 1755 LLNTTEFAQPALFAVEVALYRLL SWG+RPGLV+GHSVGEL+AAHV+G Sbjct: 686 LLNTTEFAQPALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVA 745 Query: 1756 MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRL 1815 RGRLMQALP GG M+AVQA E E+ P+LG VS+AAVNGP SVV+SGA +AVS + DRL Sbjct: 746 ARGRLMQALPAGGAMFAVQAREDEVAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRL 805 Query: 1816 AAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSA 1875 QGRRV RLAVSHAFHS LMEPM+ +F AVA E+ G P IPVISNVTGQLVA+D+ SA Sbjct: 806 RGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASA 865 Query: 1876 DYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDR 1935 DYW RHIR VRF DSV AH AGA+RF+EVGP GGLTSLIE SLA +V+VPTLRKDR Sbjct: 866 DYWARHIRAVVRFGDSVRSAHCAGASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDR 925 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXX 1995 PEP DWASV +G +RV LPTYAF H++FWLA Sbjct: 926 PEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLA------PAPSV 979 Query: 1996 XXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQL 2055 RL G S EQ AA + +VCEH AAVLGRDGAA L Sbjct: 980 SDPTAAGQIGASDGGAELLASSGFAARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGL 1039 Query: 2056 DAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHL--HHQNP 2113 DAGQAF+D+G SLSAVELRNRL +T VTL AT FD+PTPT+LA +L++ + H + Sbjct: 1040 DAGQAFADSGFNSLSAVELRNRLTAVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA 1099 Query: 2114 TGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAG 2173 A +R+DALTDLFLQ CDAGRD DGW++VALA+N RERM++PV K V LLA Sbjct: 1100 AAAANPAERIDALTDLFLQACDAGRDADGWKMVALASNTRERMSSPVRNNVSKNVALLAD 1159 Query: 2174 GRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGA 2233 G SDV V+C+PTLTVLS Y D+A AM GRHSV++L+LPGFD DALPQ+ ++++E Sbjct: 1160 GISDVVVICIPTLTVLSDQREYRDIANAMTGRHSVYSLTLPGFDSSDALPQNADMIVETV 1219 Query: 2234 AQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVNADN 2293 + AI+ VG VL+GYSSGGVLA+AL S+L+ +HQR PLGVALIDTYLPSQI N Sbjct: 1220 SNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNPLGVALIDTYLPSQIANPSM 1279 Query: 2294 PDQVGVNETGALFSRRVTSMARELDQLNXXXXXXXXXXXXXFGTWEPVVSAVPLLNMIAM 2353 + N+TG SR V +AR L++L F WEP S P+LN++A Sbjct: 1280 NEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRSMAPVLNIVAK 1339 Query: 2354 DETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATTTALHGWISGLIR 2412 D A E +R ERINRWR A AEA+YSV EVPGDHF M++TSS+A T +H WISGL+R Sbjct: 1340 DRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWISGLVR 1398 >tr|A5TZD1|A5TZD1_MYCTA Tax_Id=419947 (pks6)SubName: Full=Membrane bound polyketide synthase Pks6;[Mycobacterium tuberculosis] Length = 1402 Score = 1345 bits (3480), Expect = 0.0 Identities = 719/1155 (62%), Positives = 821/1155 (71%), Gaps = 35/1155 (3%) Query: 1 VTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC 60 +TDG +AD LQ+WF Y++ C EV+LD+P+RDLGL SIDVLAIPG+L D G C Sbjct: 1 MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSIDVLAIPGDLGDRFGFC 60 Query: 61 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADS---DTGCA---VLGNGPTNEPIAVIGMAC 114 +PDLAVWDNPSA+D+I S+L +QRSADS G A G G NEP+AVIG+ C Sbjct: 61 IPDLAVWDNPSANDLIDSLL----NQRSADSLRESHGHADRNTQGRGSINEPVAVIGVGC 116 Query: 115 RFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNK 174 RF G + G LWDFL EKK AIT YP R A G E+ G FL+DV GFDN+ Sbjct: 117 RFPGDIDGPERLWDFLTEKKCAITAYPDRGFTNA-----GTFAES--GGFLKDVAGFDNR 169 Query: 175 FFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPG 234 FFDIPPDEA MDPQQRLLLE SW ALEHAGI+P++L+LS TGVFVGVSSTDYVRL+ Sbjct: 170 FFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSRTGVFVGVSSTDYVRLVSAS 229 Query: 235 GR-KPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDL 293 + K TIWDNTGGSSSIIANR+SYFLD+ GPS+VIDTACSSSLVA HLA +SL++ +CD+ Sbjct: 230 AQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVHLACRSLSTWDCDI 289 Query: 294 AVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRA 353 A+V GTNVLISPE W GF+EAG++S TG C AFD ADGMVRGEGCGV+VL+RLSDAR Sbjct: 290 ALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEGCGVIVLQRLSDARLE 349 Query: 354 GRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSV 413 GR +LA+LTGSAVNQDG+SNGIMAPNP AQI VL++ACK A +DP EI YVEAHGTGTS+ Sbjct: 350 GRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENACKSARVDPLEIGYVEAHGTGTSL 409 Query: 414 GDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSG 473 GDRIEAHALG VFGR R + PLMIGSIKPNIGHLEGAAGIAGLIK VLM++RG LLPSG Sbjct: 410 GDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLEGAAGIAGLIKAVLMVERGSLLPSG 469 Query: 474 AFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXX 533 F PNP IPF ELGL VV+E QEWP V GRPRRAGVSSFGFGGTNAH Sbjct: 470 GFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAGVSSFGFGGTNAHVIVEEAGSVGAD 529 Query: 534 XXXXX------GPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 587 G GV+AWV+S +TA+ + AQAGRL +VRA LD DVGYSLV+TRS+ Sbjct: 530 TVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLGRYVRARPALDVVDVGYSLVSTRSV 589 Query: 588 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 647 F+HRAVVVG RDELLAGLA VV GRP GV GV P GKT FVF GQG+QWLGMG EL Sbjct: 590 FDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSEL 649 Query: 648 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 707 A YP ELDRHL PLR+V+WG D +LLNTTEFAQPALFAVEVALYRLL Sbjct: 650 YAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQDLLNTTEFAQPALFAVEVALYRLLM 709 Query: 708 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 767 SWG+RPGLV+GHSVGEL+AAHV+G RGRLMQALP GG M+AVQA E E Sbjct: 710 SWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDE 769 Query: 768 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 827 + P+LG VS+AAVNGP SVV+SGA +AVS + DRL QGRRV RLAVSHAFHS LMEPM Sbjct: 770 VAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPM 829 Query: 828 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 887 + +F AVA E+ G P IPVISNVTGQLVA+D+ SADYW RHIR VRF DSV AH AG Sbjct: 830 IAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASADYWARHIRAVVRFGDSVRSAHCAG 889 Query: 888 ATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWAS 947 A+RF+EVGP GGLTSLIE SLA +V+VPTLRKDRPEP DWAS Sbjct: 890 ASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDRPEPVSVMTAAAQGFVSGMGLDWAS 949 Query: 948 VLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXX 1007 V +G +RV LPTYAF H++FWLA Sbjct: 950 VFSGYRPKRVELPTYAFQHQKFWLA------PAPSVSDPTAAGQIGASDGGAELLASSGF 1003 Query: 1008 XXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLK 1067 RL G S EQ AA + +VCEH AAVLGRDGAA LDAGQAF+D+G SLSAVELRNRL Sbjct: 1004 AARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSGFNSLSAVELRNRLT 1063 Query: 1068 TLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 +T VTL AT FD+PTPT+LA +L++ + SA AAA RID + C Sbjct: 1064 AVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA-AAAANPAERIDALTDLFLQAC-- 1120 Query: 1128 PGGVSSPAQLWQLVA 1142 A W++VA Sbjct: 1121 --DAGRDADGWKMVA 1133 Score = 1326 bits (3431), Expect = 0.0 Identities = 729/1379 (52%), Positives = 889/1379 (64%), Gaps = 35/1379 (2%) Query: 1051 DAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQN-RSAPAAAVR 1109 D GL S+ + + L G + +D P+ L D LL+ + R + A R Sbjct: 38 DLGLKSIDVLAIPGDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESHGHADR 97 Query: 1110 T---RVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPD 1166 R I+EP+A++G+GCR+PG + P +LW + I +P DRG+ Sbjct: 98 NTQGRGSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAITAYP-DRGF--------- 147 Query: 1167 PDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQA 1226 T+ GGF+ DVA FD FF I P EAL MDPQQRLLLE SWEALE AGI P++ Sbjct: 148 --TNAGTFAESGGFLKDVAGFDNRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPES 205 Query: 1227 LRGSSTGVFVGIYGDGY-GLGTSQAQW----YADTGHITSVASGRISYCLGLAGPAISVD 1281 LR S TGVFVG+ Y L ++ AQ + +TG +S+ + RISY L + GP+I +D Sbjct: 206 LRLSRTGVFVGVSSTDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVID 265 Query: 1282 TACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADA 1341 TACSSSLVA+HLA SL +CD+AL GG+ VL +P + GF L+ G C AF + Sbjct: 266 TACSSSLVAVHLACRSLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKS 325 Query: 1342 ADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISA 1401 ADG EG G++VLQRLSDAR G+ +LAIL GSAVNQDG SNG+ AP+ AQ V+ Sbjct: 326 ADGMVRGEGCGVIVLQRLSDARLEGRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLEN 385 Query: 1402 ALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQ 1461 A A + ++ VEAHGTGT LGD IEA AL +GR PL +GSIK N+GH + Sbjct: 386 ACKSARVDPLEIGYVEAHGTGTSLGDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLE 445 Query: 1462 AAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAG 1521 AAG+AG+IK V + L + +P+ + ++ ++++ E +EWP V GRPRRAG Sbjct: 446 GAAGIAGLIKAVLMVERGSLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAG 505 Query: 1522 VSSFGVSGTNAHXXXXXXXXXXXXXXXXX------GPGVLAWVVSARTAAGVGAQAGRLL 1575 VSSFG GTNAH G GV+AWV+S +TA+ + AQAGRL Sbjct: 506 VSSFGFGGTNAHVIVEEAGSVGADTVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLG 565 Query: 1576 EFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVA 1635 +VRA LD DVGYSLV+TRS+F+HRAVVVG RDELLAGLA VV GRP GV GV Sbjct: 566 RYVRARPALDVVDVGYSLVSTRSVFDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVG 625 Query: 1636 MPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAE 1695 P GKT FVF GQG+QWLGMG EL A YP ELDRHL PLR+V+WG D + Sbjct: 626 KPAGKTAFVFAGQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQD 685 Query: 1696 LLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXX 1755 LLNTTEFAQPALFAVEVALYRLL SWG+RPGLV+GHSVGEL+AAHV+G Sbjct: 686 LLNTTEFAQPALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVA 745 Query: 1756 MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRL 1815 RGRLMQALP GG M+AVQA E E+ P+LG VS+AAVNGP SVV+SGA +AVS + DRL Sbjct: 746 ARGRLMQALPAGGAMFAVQAREDEVAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRL 805 Query: 1816 AAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSA 1875 QGRRV RLAVSHAFHS LMEPM+ +F AVA E+ G P IPVISNVTGQLVA+D+ SA Sbjct: 806 RGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASA 865 Query: 1876 DYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDR 1935 DYW RHIR VRF DSV AH AGA+RF+EVGP GGLTSLIE SLA +V+VPTLRKDR Sbjct: 866 DYWARHIRAVVRFGDSVRSAHCAGASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDR 925 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXX 1995 PEP DWASV +G +RV LPTYAF H++FWLA Sbjct: 926 PEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLA------PAPSV 979 Query: 1996 XXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQL 2055 RL G S EQ AA + +VCEH AAVLGRDGAA L Sbjct: 980 SDPTAAGQIGASDGGAELLASSGFAARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGL 1039 Query: 2056 DAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHL--HHQNP 2113 DAGQAF+D+G SLSAVELRNRL +T VTL AT FD+PTPT+LA +L++ + H + Sbjct: 1040 DAGQAFADSGFNSLSAVELRNRLTAVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA 1099 Query: 2114 TGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAG 2173 A +R+DALTDLFLQ CDAGRD DGW++VALA+N RERM++PV K V LLA Sbjct: 1100 AAAANPAERIDALTDLFLQACDAGRDADGWKMVALASNTRERMSSPVRNNVSKNVALLAD 1159 Query: 2174 GRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGA 2233 G SDV V+C+PTLTVLS Y D+A AM GRHSV++L+LPGFD DALPQ+ ++++E Sbjct: 1160 GISDVVVICIPTLTVLSDQREYRDIANAMTGRHSVYSLTLPGFDSSDALPQNADMIVETV 1219 Query: 2234 AQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVNADN 2293 + AI+ VG VL+GYSSGGVLA+AL S+L+ +HQR PLGVALIDTYLPSQI N Sbjct: 1220 SNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNPLGVALIDTYLPSQIANPSM 1279 Query: 2294 PDQVGVNETGALFSRRVTSMARELDQLNXXXXXXXXXXXXXFGTWEPVVSAVPLLNMIAM 2353 + N+TG SR V +AR L++L F WEP S P+LN++A Sbjct: 1280 NEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRSMAPVLNIVAK 1339 Query: 2354 DETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATTTALHGWISGLIR 2412 D A E +R ERINRWR A AEA+YSV EVPGDHF M++TSS+A T +H WISGL+R Sbjct: 1340 DRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWISGLVR 1398 >tr|A5WJB4|A5WJB4_MYCTF Tax_Id=336982 SubName: Full=Membrane bound polyketide synthase pks6;[Mycobacterium tuberculosis] Length = 1402 Score = 1345 bits (3480), Expect = 0.0 Identities = 719/1155 (62%), Positives = 821/1155 (71%), Gaps = 35/1155 (3%) Query: 1 VTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC 60 +TDG +AD LQ+WF Y++ C EV+LD+P+RDLGL SIDVLAIPG+L D G C Sbjct: 1 MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSIDVLAIPGDLGDRFGFC 60 Query: 61 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADS---DTGCA---VLGNGPTNEPIAVIGMAC 114 +PDLAVWDNPSA+D+I S+L +QRSADS G A G G NEP+AVIG+ C Sbjct: 61 IPDLAVWDNPSANDLIDSLL----NQRSADSLRESHGHADRNTQGRGSINEPVAVIGVGC 116 Query: 115 RFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNK 174 RF G + G LWDFL EKK AIT YP R A G E+ G FL+DV GFDN+ Sbjct: 117 RFPGDIDGPERLWDFLTEKKCAITAYPDRGFTNA-----GTFAES--GGFLKDVAGFDNR 169 Query: 175 FFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPG 234 FFDIPPDEA MDPQQRLLLE SW ALEHAGI+P++L+LS TGVFVGVSSTDYVRL+ Sbjct: 170 FFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSRTGVFVGVSSTDYVRLVSAS 229 Query: 235 GR-KPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDL 293 + K TIWDNTGGSSSIIANR+SYFLD+ GPS+VIDTACSSSLVA HLA +SL++ +CD+ Sbjct: 230 AQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVHLACRSLSTWDCDI 289 Query: 294 AVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRA 353 A+V GTNVLISPE W GF+EAG++S TG C AFD ADGMVRGEGCGV+VL+RLSDAR Sbjct: 290 ALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEGCGVIVLQRLSDARLE 349 Query: 354 GRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSV 413 GR +LA+LTGSAVNQDG+SNGIMAPNP AQI VL++ACK A +DP EI YVEAHGTGTS+ Sbjct: 350 GRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENACKSARVDPLEIGYVEAHGTGTSL 409 Query: 414 GDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSG 473 GDRIEAHALG VFGR R + PLMIGSIKPNIGHLEGAAGIAGLIK VLM++RG LLPSG Sbjct: 410 GDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLEGAAGIAGLIKAVLMVERGSLLPSG 469 Query: 474 AFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXX 533 F PNP IPF ELGL VV+E QEWP V GRPRRAGVSSFGFGGTNAH Sbjct: 470 GFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAGVSSFGFGGTNAHVIVEEAGSVGAD 529 Query: 534 XXXXX------GPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 587 G GV+AWV+S +TA+ + AQAGRL +VRA LD DVGYSLV+TRS+ Sbjct: 530 TVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLGRYVRARPALDVVDVGYSLVSTRSV 589 Query: 588 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 647 F+HRAVVVG RDELLAGLA VV GRP GV GV P GKT FVF GQG+QWLGMG EL Sbjct: 590 FDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSEL 649 Query: 648 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 707 A YP ELDRHL PLR+V+WG D +LLNTTEFAQPALFAVEVALYRLL Sbjct: 650 YAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQDLLNTTEFAQPALFAVEVALYRLLM 709 Query: 708 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 767 SWG+RPGLV+GHSVGEL+AAHV+G RGRLMQALP GG M+AVQA E E Sbjct: 710 SWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDE 769 Query: 768 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 827 + P+LG VS+AAVNGP SVV+SGA +AVS + DRL QGRRV RLAVSHAFHS LMEPM Sbjct: 770 VAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPM 829 Query: 828 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 887 + +F AVA E+ G P IPVISNVTGQLVA+D+ SADYW RHIR VRF DSV AH AG Sbjct: 830 IAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASADYWARHIRAVVRFGDSVRSAHCAG 889 Query: 888 ATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWAS 947 A+RF+EVGP GGLTSLIE SLA +V+VPTLRKDRPEP DWAS Sbjct: 890 ASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDRPEPVSVMTAAAQGFVSGMGLDWAS 949 Query: 948 VLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXX 1007 V +G +RV LPTYAF H++FWLA Sbjct: 950 VFSGYRPKRVELPTYAFQHQKFWLA------PAPSVSDPTAAGQIGASDGGAELLASSGF 1003 Query: 1008 XXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLK 1067 RL G S EQ AA + +VCEH AAVLGRDGAA LDAGQAF+D+G SLSAVELRNRL Sbjct: 1004 AARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSGFNSLSAVELRNRLT 1063 Query: 1068 TLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 +T VTL AT FD+PTPT+LA +L++ + SA AAA RID + C Sbjct: 1064 AVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA-AAAANPAERIDALTDLFLQAC-- 1120 Query: 1128 PGGVSSPAQLWQLVA 1142 A W++VA Sbjct: 1121 --DAGRDADGWKMVA 1133 Score = 1326 bits (3431), Expect = 0.0 Identities = 729/1379 (52%), Positives = 889/1379 (64%), Gaps = 35/1379 (2%) Query: 1051 DAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQN-RSAPAAAVR 1109 D GL S+ + + L G + +D P+ L D LL+ + R + A R Sbjct: 38 DLGLKSIDVLAIPGDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESHGHADR 97 Query: 1110 T---RVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPD 1166 R I+EP+A++G+GCR+PG + P +LW + I +P DRG+ Sbjct: 98 NTQGRGSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAITAYP-DRGF--------- 147 Query: 1167 PDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQA 1226 T+ GGF+ DVA FD FF I P EAL MDPQQRLLLE SWEALE AGI P++ Sbjct: 148 --TNAGTFAESGGFLKDVAGFDNRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPES 205 Query: 1227 LRGSSTGVFVGIYGDGY-GLGTSQAQW----YADTGHITSVASGRISYCLGLAGPAISVD 1281 LR S TGVFVG+ Y L ++ AQ + +TG +S+ + RISY L + GP+I +D Sbjct: 206 LRLSRTGVFVGVSSTDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVID 265 Query: 1282 TACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADA 1341 TACSSSLVA+HLA SL +CD+AL GG+ VL +P + GF L+ G C AF + Sbjct: 266 TACSSSLVAVHLACRSLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKS 325 Query: 1342 ADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISA 1401 ADG EG G++VLQRLSDAR G+ +LAIL GSAVNQDG SNG+ AP+ AQ V+ Sbjct: 326 ADGMVRGEGCGVIVLQRLSDARLEGRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLEN 385 Query: 1402 ALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQ 1461 A A + ++ VEAHGTGT LGD IEA AL +GR PL +GSIK N+GH + Sbjct: 386 ACKSARVDPLEIGYVEAHGTGTSLGDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLE 445 Query: 1462 AAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAG 1521 AAG+AG+IK V + L + +P+ + ++ ++++ E +EWP V GRPRRAG Sbjct: 446 GAAGIAGLIKAVLMVERGSLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAG 505 Query: 1522 VSSFGVSGTNAHXXXXXXXXXXXXXXXXX------GPGVLAWVVSARTAAGVGAQAGRLL 1575 VSSFG GTNAH G GV+AWV+S +TA+ + AQAGRL Sbjct: 506 VSSFGFGGTNAHVIVEEAGSVGADTVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLG 565 Query: 1576 EFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVA 1635 +VRA LD DVGYSLV+TRS+F+HRAVVVG RDELLAGLA VV GRP GV GV Sbjct: 566 RYVRARPALDVVDVGYSLVSTRSVFDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVG 625 Query: 1636 MPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAE 1695 P GKT FVF GQG+QWLGMG EL A YP ELDRHL PLR+V+WG D + Sbjct: 626 KPAGKTAFVFAGQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQD 685 Query: 1696 LLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXX 1755 LLNTTEFAQPALFAVEVALYRLL SWG+RPGLV+GHSVGEL+AAHV+G Sbjct: 686 LLNTTEFAQPALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVA 745 Query: 1756 MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRL 1815 RGRLMQALP GG M+AVQA E E+ P+LG VS+AAVNGP SVV+SGA +AVS + DRL Sbjct: 746 ARGRLMQALPAGGAMFAVQAREDEVAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRL 805 Query: 1816 AAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSA 1875 QGRRV RLAVSHAFHS LMEPM+ +F AVA E+ G P IPVISNVTGQLVA+D+ SA Sbjct: 806 RGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASA 865 Query: 1876 DYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDR 1935 DYW RHIR VRF DSV AH AGA+RF+EVGP GGLTSLIE SLA +V+VPTLRKDR Sbjct: 866 DYWARHIRAVVRFGDSVRSAHCAGASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDR 925 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXX 1995 PEP DWASV +G +RV LPTYAF H++FWLA Sbjct: 926 PEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLA------PAPSV 979 Query: 1996 XXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQL 2055 RL G S EQ AA + +VCEH AAVLGRDGAA L Sbjct: 980 SDPTAAGQIGASDGGAELLASSGFAARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGL 1039 Query: 2056 DAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHL--HHQNP 2113 DAGQAF+D+G SLSAVELRNRL +T VTL AT FD+PTPT+LA +L++ + H + Sbjct: 1040 DAGQAFADSGFNSLSAVELRNRLTAVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA 1099 Query: 2114 TGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAG 2173 A +R+DALTDLFLQ CDAGRD DGW++VALA+N RERM++PV K V LLA Sbjct: 1100 AAAANPAERIDALTDLFLQACDAGRDADGWKMVALASNTRERMSSPVRNNVSKNVALLAD 1159 Query: 2174 GRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGA 2233 G SDV V+C+PTLTVLS Y D+A AM GRHSV++L+LPGFD DALPQ+ ++++E Sbjct: 1160 GISDVVVICIPTLTVLSDQREYRDIANAMTGRHSVYSLTLPGFDSSDALPQNADMIVETV 1219 Query: 2234 AQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVNADN 2293 + AI+ VG VL+GYSSGGVLA+AL S+L+ +HQR PLGVALIDTYLPSQI N Sbjct: 1220 SNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNPLGVALIDTYLPSQIANPSM 1279 Query: 2294 PDQVGVNETGALFSRRVTSMARELDQLNXXXXXXXXXXXXXFGTWEPVVSAVPLLNMIAM 2353 + N+TG SR V +AR L++L F WEP S P+LN++A Sbjct: 1280 NEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRSMAPVLNIVAK 1339 Query: 2354 DETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATTTALHGWISGLIR 2412 D A E +R ERINRWR A AEA+YSV EVPGDHF M++TSS+A T +H WISGL+R Sbjct: 1340 DRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWISGLVR 1398 >tr|A4KE93|A4KE93_MYCTU Tax_Id=395095 SubName: Full=Membrane bound polyketide synthase pks6;[Mycobacterium tuberculosis str. Haarlem] Length = 1402 Score = 1344 bits (3478), Expect = 0.0 Identities = 718/1155 (62%), Positives = 821/1155 (71%), Gaps = 35/1155 (3%) Query: 1 VTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGIC 60 +TDG +AD LQ+WF Y++ C EV+LD+P+RDLGL SIDVLAIPG+L D G C Sbjct: 1 MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSIDVLAIPGDLGDRFGFC 60 Query: 61 VPDLAVWDNPSAHDVIKSVLGGDGSQRSADS---DTGCA---VLGNGPTNEPIAVIGMAC 114 +PDLAVWDNPSA+D+I S+L +QRSADS G A G G NEP+AVIG+ C Sbjct: 61 IPDLAVWDNPSANDLIDSLL----NQRSADSLRESHGHADRNTQGRGSINEPVAVIGVGC 116 Query: 115 RFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGCFLEDVEGFDNK 174 RF G + G LWDFL EKK AIT YP R A G E+ G FL+DV GFDN+ Sbjct: 117 RFPGDIDGPERLWDFLTEKKCAITAYPDRGFTNA-----GTFAES--GGFLKDVAGFDNR 169 Query: 175 FFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPG 234 FFDIPPDEA MDPQQRLLLE SW ALEHAGI+P++L+LS TGVFVGVSSTDYVRL+ Sbjct: 170 FFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSRTGVFVGVSSTDYVRLVSAS 229 Query: 235 GR-KPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDL 293 + K TIWDNTGGSSSIIANR+SYFLD+ GPS+VIDTACSSSLVA HLA +SL++ +CD+ Sbjct: 230 AQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVHLACRSLSTWDCDI 289 Query: 294 AVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRA 353 A+V GTNVLISPE W GF+EAG++S TG C AFD ADGMVRGEGCGV+VL+RLSDAR Sbjct: 290 ALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEGCGVIVLQRLSDARLE 349 Query: 354 GRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSV 413 GR +LA+LTGSAVNQDG+SNGIMAPNP AQI VL++ACK A +DP EI YVEAHGTGTS+ Sbjct: 350 GRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENACKSARVDPLEIGYVEAHGTGTSL 409 Query: 414 GDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSG 473 GDRIEAHALG VFGR R + PLMIGSIKPNIGHLEGAAGIAGLIK VLM++RG LLPSG Sbjct: 410 GDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLEGAAGIAGLIKAVLMVERGSLLPSG 469 Query: 474 AFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXX 533 F PNP IPF ELGL VV+E QEWP V GRPRRAGVSSFGFGGTNAH Sbjct: 470 GFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAGVSSFGFGGTNAHVIVEEAGSVGAD 529 Query: 534 XXXXX------GPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 587 G GV+AWV+S +TA+ + AQAGRL +VRA LD DVGYSLV+TRS+ Sbjct: 530 TVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLGRYVRARPALDVVDVGYSLVSTRSV 589 Query: 588 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 647 F+HRAVVVG RDELLAGLA VV GRP GV GV P GKT FVF GQG+QWLGMG EL Sbjct: 590 FDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSEL 649 Query: 648 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 707 A YP ELDRHL PLR+V+WG D +LLNTTEFAQPALFAVEVALYRL+ Sbjct: 650 YAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQDLLNTTEFAQPALFAVEVALYRLVM 709 Query: 708 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 767 SWG+RPGLV+GHSVGEL+AAHV+G RGRLMQALP GG M+AVQA E E Sbjct: 710 SWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDE 769 Query: 768 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 827 + P+LG VS+AAVNGP SVV+SGA +AVS + DRL QGRRV RLAVSHAFHS LMEPM Sbjct: 770 VAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPM 829 Query: 828 LEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAG 887 + +F AVA E+ G P IPVISNVTGQLVA+D+ SADYW RHIR VRF DSV AH AG Sbjct: 830 IAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASADYWARHIRAVVRFGDSVRSAHCAG 889 Query: 888 ATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWAS 947 A+RF+EVGP GGLTSLIE SLA +V+VPTLRKDRPEP DWAS Sbjct: 890 ASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDRPEPVSVMTAAAQGFVSGMGLDWAS 949 Query: 948 VLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXX 1007 V +G +RV LPTYAF H++FWLA Sbjct: 950 VFSGYRPKRVELPTYAFQHQKFWLA------PAPSVSDPTAAGQIGASDGGAELLASSGF 1003 Query: 1008 XXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLK 1067 RL G S EQ AA + +VCEH AAVLGRDGAA LDAGQAF+D+G SLSAVELRNRL Sbjct: 1004 AARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSGFNSLSAVELRNRLT 1063 Query: 1068 TLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 +T VTL AT FD+PTPT+LA +L++ + SA AAA RID + C Sbjct: 1064 AVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA-AAAANPAERIDALTDVFLQAC-- 1120 Query: 1128 PGGVSSPAQLWQLVA 1142 A W++VA Sbjct: 1121 --DAGRDADGWKMVA 1133 Score = 1323 bits (3425), Expect = 0.0 Identities = 727/1379 (52%), Positives = 889/1379 (64%), Gaps = 35/1379 (2%) Query: 1051 DAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQN-RSAPAAAVR 1109 D GL S+ + + L G + +D P+ L D LL+ + R + A R Sbjct: 38 DLGLKSIDVLAIPGDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESHGHADR 97 Query: 1110 T---RVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPD 1166 R I+EP+A++G+GCR+PG + P +LW + I +P DRG+ Sbjct: 98 NTQGRGSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAITAYP-DRGF--------- 147 Query: 1167 PDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQA 1226 T+ GGF+ DVA FD FF I P EAL MDPQQRLLLE SWEALE AGI P++ Sbjct: 148 --TNAGTFAESGGFLKDVAGFDNRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPES 205 Query: 1227 LRGSSTGVFVGIYGDGY-GLGTSQAQW----YADTGHITSVASGRISYCLGLAGPAISVD 1281 LR S TGVFVG+ Y L ++ AQ + +TG +S+ + RISY L + GP+I +D Sbjct: 206 LRLSRTGVFVGVSSTDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVID 265 Query: 1282 TACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADA 1341 TACSSSLVA+HLA SL +CD+AL GG+ VL +P + GF L+ G C AF + Sbjct: 266 TACSSSLVAVHLACRSLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKS 325 Query: 1342 ADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISA 1401 ADG EG G++VLQRLSDAR G+ +LAIL GSAVNQDG SNG+ AP+ AQ V+ Sbjct: 326 ADGMVRGEGCGVIVLQRLSDARLEGRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLEN 385 Query: 1402 ALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQ 1461 A A + ++ VEAHGTGT LGD IEA AL +GR PL +GSIK N+GH + Sbjct: 386 ACKSARVDPLEIGYVEAHGTGTSLGDRIEAHALGMVFGRKRPGSGPLMIGSIKPNIGHLE 445 Query: 1462 AAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAG 1521 AAG+AG+IK V + L + +P+ + ++ ++++ E +EWP V GRPRRAG Sbjct: 446 GAAGIAGLIKAVLMVERGSLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAGRPRRAG 505 Query: 1522 VSSFGVSGTNAHXXXXXXXXXXXXXXXXX------GPGVLAWVVSARTAAGVGAQAGRLL 1575 VSSFG GTNAH G GV+AWV+S +TA+ + AQAGRL Sbjct: 506 VSSFGFGGTNAHVIVEEAGSVGADTVSGRADVGGSGGGVVAWVISGKTASALAAQAGRLG 565 Query: 1576 EFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVA 1635 +VRA LD DVGYSLV+TRS+F+HRAVVVG RDELLAGLA VV GRP GV GV Sbjct: 566 RYVRARPALDVVDVGYSLVSTRSVFDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVG 625 Query: 1636 MPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAE 1695 P GKT FVF GQG+QWLGMG EL A YP ELDRHL PLR+V+WG D + Sbjct: 626 KPAGKTAFVFAGQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQD 685 Query: 1696 LLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXX 1755 LLNTTEFAQPALFAVEVALYRL+ SWG+RPGLV+GHSVGEL+AAHV+G Sbjct: 686 LLNTTEFAQPALFAVEVALYRLVMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVA 745 Query: 1756 MRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRL 1815 RGRLMQALP GG M+AVQA E E+ P+LG VS+AAVNGP SVV+SGA +AVS + DRL Sbjct: 746 ARGRLMQALPAGGAMFAVQAREDEVAPMLGHDVSIAAVNGPASVVISGAHDAVSAIADRL 805 Query: 1816 AAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSA 1875 QGRRV RLAVSHAFHS LMEPM+ +F AVA E+ G P IPVISNVTGQLVA+D+ SA Sbjct: 806 RGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSVGLPTIPVISNVTGQLVADDFASA 865 Query: 1876 DYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDR 1935 DYW RHIR VRF DSV AH AGA+RF+EVGP GGLTSLIE SLA +V+VPTLRKDR Sbjct: 866 DYWARHIRAVVRFGDSVRSAHCAGASRFIEVGPGGGLTSLIEASLADAQIVSVPTLRKDR 925 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXX 1995 PEP DWASV +G +RV LPTYAF H++FWLA Sbjct: 926 PEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLA------PAPSV 979 Query: 1996 XXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQL 2055 RL G S EQ AA + +VCEH AAVLGRDGAA L Sbjct: 980 SDPTAAGQIGASDGGAELLASSGFAARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGL 1039 Query: 2056 DAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHL--HHQNP 2113 DAGQAF+D+G SLSAVELRNRL +T VTL AT FD+PTPT+LA +L++ + H + Sbjct: 1040 DAGQAFADSGFNSLSAVELRNRLTAVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSA 1099 Query: 2114 TGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAG 2173 A +R+DALTD+FLQ CDAGRD DGW++VALA+N RERM++PV K V LLA Sbjct: 1100 AAAANPAERIDALTDVFLQACDAGRDADGWKMVALASNTRERMSSPVRNNVSKNVALLAD 1159 Query: 2174 GRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGA 2233 G SDV V+C+PTLTVLS Y D+A AM GRHSV++L+LPGFD DALPQ+ ++++E Sbjct: 1160 GISDVVVICIPTLTVLSDQREYRDIANAMTGRHSVYSLTLPGFDSSDALPQNADMIVETV 1219 Query: 2234 AQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVNADN 2293 + AI+ VG VL+GYSSGGVLA+AL S+L+ +HQR PLGVALIDTYLPSQI N Sbjct: 1220 SNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNPLGVALIDTYLPSQIANPSM 1279 Query: 2294 PDQVGVNETGALFSRRVTSMARELDQLNXXXXXXXXXXXXXFGTWEPVVSAVPLLNMIAM 2353 + N+TG SR V +AR L++L F WEP S P+LN++A Sbjct: 1280 NEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRSMAPVLNIVAK 1339 Query: 2354 DETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATTTALHGWISGLIR 2412 D A E +R ERINRWR A AEA+YSV EVPGDHF M++TSS+A T +H WISGL+R Sbjct: 1340 DRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWISGLVR 1398 >tr|A0ACH3|A0ACH3_STRAM Tax_Id=278992 SubName: Full=Putative type I polyketide synthase;[Streptomyces ambofaciens ATCC 23877] Length = 5771 Score = 1310 bits (3389), Expect = 0.0 Identities = 838/1908 (43%), Positives = 1057/1908 (55%), Gaps = 73/1908 (3%) Query: 104 NEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYGC 163 +E A+IG ACR G G PLW+ LA AITE P+ R + G Sbjct: 9 SEAFAIIGYACRLPG-APGPAPLWELLATGTDAITEIPSDRARVPSVT---------RGG 58 Query: 164 FLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVS 223 F+E FD FF + P EAA DPQQRL LE +W ALE A LP L S TGVF+G Sbjct: 59 FIERAADFDAGFFGMSPREAAATDPQQRLALELAWEALEDARHLPAGLGGSRTGVFLGAI 118 Query: 224 STDYVRLLFPGGRKPTIWDNTGG-SSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLA 282 DY LL G + G +IANRLSY L ++GPSL +D SSSLV+ HLA Sbjct: 119 WDDYAALLHRAGDAGIDRHSMPGLQRGLIANRLSYTLGLHGPSLTVDAGQSSSLVSVHLA 178 Query: 283 RKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVV 342 +SLA GE +LA+ G N++++P+ G +SP G C FDARA+G VRGEG GVV Sbjct: 179 CESLARGESELALAGGVNLVLAPDSTVSALRFGGLSPDGRCFTFDARANGFVRGEGGGVV 238 Query: 343 VLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEID 402 VL+ L+ A G + AV+ GSAVN DG + P+ AQ +VL +A A I P + Sbjct: 239 VLKPLARALTDGDRIHAVVRGSAVNNDGGGPSLTTPSAAAQEAVLRAAHARAGIAPDAVG 298 Query: 403 YVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVL 462 YVE HGTGT VGD +EA ALG G R A PL +GS+K NIGHLEGAAGIAGL+K L Sbjct: 299 YVELHGTGTPVGDPVEAAALGAALGTARTA--PLPVGSVKTNIGHLEGAAGIAGLLKAAL 356 Query: 463 MLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHX 522 +++RG + PS F P IP L L V Q +G GVSSFG GGTN H Sbjct: 357 VVERGVVPPSLNFASPPAGIPLERLNLRV----QTAAGPLGGEGFVGVSSFGMGGTNCHL 412 Query: 523 XXXXXXXXXXXXXXXX--------GPGV------LAWVVSARTAAGVGAQAGRLLEFVRA 568 PG + +VS TA + AQA RL + V Sbjct: 413 VLGPAPDPVARPAAEPPAHAAVPPAPGSDRTTPPVPVLVSGHTAQALRAQAARLKDAVE- 471 Query: 569 GRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGK 628 G +L DV +SL TTR+ F RAV++ R++LLA L+ V G P GV+ G A G + Sbjct: 472 GADLAVADVAHSLATTRTRFARRAVLLAEDREQLLAQLSAVAAGLPATGVSEGAARTG-R 530 Query: 629 TVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGAD-AELLNT 687 +F GQG+QW M L L H L +V+ GA+ A L Sbjct: 531 LAMIFSGQGSQWPAMATGLLDTDEVFTRAIHACAEALAPHTDFSLTDVLRGAEGAPTLER 590 Query: 688 TEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGR 747 + QPALFAV VAL S G+ P V GHS GE++AA V+G +R R Sbjct: 591 VDVVQPALFAVMVALAETWRSLGVVPDAVAGHSQGEIAAACVAGALSLPDAAKVVALRSR 650 Query: 748 LMQALPGGGVMYAVQAGEQELRPLL--GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAA 805 + AL G G M +VQAG +RP L +S+AA NGP +VV+SG +A+ R Sbjct: 651 AIGALAGQGGMLSVQAGAARVRPWLETAPALSIAADNGPTAVVVSGPVDALDGFAARCVT 710 Query: 806 QGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADY 865 G RR+ V +A HS +E + ++ ++ +P +S VTG+ A Y Sbjct: 711 YGVETRRIPVDYASHSAHVELIHDELLTALADIEPRTSEVPFLSTVTGEWTDTAGLDAAY 770 Query: 866 WVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV---VAVPTLRKD 922 W R++R V F+ +V VE P L + + + LA++ V +LR Sbjct: 771 WYRNLRSTVEFSAAVRRLADEDFRFIVEATPHPVLVAAVRDILAELDAPDTAVVGSLR-- 828 Query: 923 RPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL-ADRFXXXXXX 981 R E D L G V LPTYAF ER W + Sbjct: 829 RGEGGRARLLGSAAELLAHGRDVR--LPAPPGTVVDLPTYAFQRERHWRPGEAAALWDGT 886 Query: 982 XXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAA 1041 RL+ LS + V ++ H A V G A Sbjct: 887 GEPVRDAAAPDTGADPDTAAVPDDSLRDRLRALSPQSARGTVRELIRSHAAVVGGFAAAE 946 Query: 1042 QLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNR 1101 ++D Q F G+ SL+ VELR RL T TG++L T FD+PTP A HL L ++ Sbjct: 947 EVDPEQTFKALGIASLTLVELRTRLATATGLSLPPTFLFDHPTPAAAARHLCDALRGEDA 1006 Query: 1102 SAPAAAVRTR--VRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDI 1159 + P+ A+ D+P+ IV M CR+PGG+ SPA LW+ ++ G +V+ P DRGW Sbjct: 1007 ARPSRAMPAPQPADADDPVVIVSMACRFPGGIDSPAALWEALSEGREVLTGLPEDRGWQ- 1065 Query: 1160 ERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALED 1219 P AL GGF+ D+A FD FGISP EA+AMDPQQRLLLE +WEALE Sbjct: 1066 -----PALAALETPLPTAGGFLDDIAGFDAALFGISPREAVAMDPQQRLLLEVTWEALER 1120 Query: 1220 AGIDPQALRGSSTGVFVGIYGDGYGLGTSQ----AQWYADTGHITSVASGRISYCLGLAG 1275 G DP LRGS TGVFVG YG + ++ Y TG SVASGRI+Y L G Sbjct: 1121 LGTDPTDLRGSRTGVFVGATAQDYGPRMHEPAESSEGYLLTGTTASVASGRIAYAFALDG 1180 Query: 1276 PAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRC 1335 PA++VDTACSSSLVALHLAA SLRAGEC ALAGG T++ATP + + F+RQ GL+ DGRC Sbjct: 1181 PAVTVDTACSSSLVALHLAAQSLRAGECSTALAGGVTLMATPGVLVEFARQDGLSPDGRC 1240 Query: 1336 KAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQ 1395 KAF ADGTG+SEGAGMLVL+RLSDA GQ VLA+L GSAVN DGASNGLTAP+G AQ Sbjct: 1241 KAFGARADGTGWSEGAGMLVLRRLSDALADGQHVLAVLRGSAVNSDGASNGLTAPNGLAQ 1300 Query: 1396 QRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKS 1455 +RVI AAL AG+ +DVD+VEAHGTGTRLGDPIEAQALLATYG++ + PLWLGS+KS Sbjct: 1301 RRVIRAALDAAGLRPSDVDMVEAHGTGTRLGDPIEAQALLATYGQERDAERPLWLGSLKS 1360 Query: 1456 NMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVG 1515 N+GH+Q+AAGVAGVIK V A+RH +LP TLH D+P+ HVDWS G V+LLTE P Sbjct: 1361 NIGHTQSAAGVAGVIKTVLALRHGVLPRTLHADEPTPHVDWSAGAVRLLTENVTLPP-AD 1419 Query: 1516 RPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXGPGV-LAWVVSARTAAGVGAQAGRL 1574 RP RAGVSSFG+SGTNAH GP + L ++S AA + QA RL Sbjct: 1420 RPYRAGVSSFGISGTNAHAVIEAAPEPAVPDEGTPGPRLALPVLLSGHGAAALRDQAARL 1479 Query: 1575 LEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGV 1634 F+ A + + S TTR +HRA + A R+EL A L V EG GV GV Sbjct: 1480 RAFLDAEPSVPPTAIARSSATTRFPLDHRAALFAADREELAARLDAVAEGHDAAGVLHGV 1539 Query: 1635 AMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADA 1694 A P G+T F+F GQG+Q LGMGREL +P +D L RPLR VV+G DA Sbjct: 1540 ASP-GRTGFLFTGQGSQRLGMGRELYGAFPVFADAFDAVCARVD--LERPLRGVVFGEDA 1596 Query: 1695 ELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXX 1754 LL T +AQ LFA+EVAL+RL+ESWG+ P +++GHS+GEL+AAH +G Sbjct: 1597 GLLERTVYAQAGLFALEVALFRLVESWGVVPDVLVGHSIGELAAAHCAGVLSLEDACALV 1656 Query: 1755 XMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDR 1814 RGRLM ALP GG M AV+ E ELR L + V +AAVNGP SV +SG +AV+ + +R Sbjct: 1657 SARGRLMDALPAGGAMLAVEVAEGELR--LPDGVDLAAVNGPTSVTVSGEADAVAGLEER 1714 Query: 1815 LAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGS 1874 L A+ RV+RLAVSHAFHS LMEPML F AVA+ + P IPV + G + + Sbjct: 1715 LRAREIRVKRLAVSHAFHSRLMEPMLADFAAVAESLTYHAPQIPVRTTAPGAI-----DT 1769 Query: 1875 ADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKD 1934 +YWV IRE VRFAD++ A F+E+GP G L++L+ LA+ VAVP LR+ Sbjct: 1770 PEYWVGQIREPVRFADAL--ASLPEVRTFLELGPDGVLSALVPVLLAE--AVAVPLLRRG 1825 Query: 1935 RPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 + + DW +V + V LP+YAF R+W Sbjct: 1826 Q-DGTRPAHAAAVLWTRGVPLDWTAVTGTGTSRPVELPSYAFQRTRYW 1872 Score = 952 bits (2462), Expect = 0.0 Identities = 524/978 (53%), Positives = 635/978 (64%), Gaps = 24/978 (2%) Query: 1011 LQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLT 1070 L L + E+ AV +V AAVLG +D G+ F D G SL+ VELRNRL T Sbjct: 2606 LAALPEPERTRAVEELVRTTVAAVLGHSSGTGVDTGRTFKDLGFDSLTGVELRNRLAAAT 2665 Query: 1071 GVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGG 1130 G+ L+AT F +P+P L HL L A R DEPIA+V M CRYPGG Sbjct: 2666 GLRLAATLVFSHPSPAALTAHLCEELSGTAADAAVPRSRKSAAADEPIAVVAMSCRYPGG 2725 Query: 1131 VSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPG 1190 V P +LW++V G D I FP DRGWD+ RL DPDP G TY RHGGF+ D ADFD Sbjct: 2726 VDGPEELWRMVREGRDGITGFPTDRGWDLARLHDPDPSRPGTTYARHGGFLHDAADFDAE 2785 Query: 1191 FFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS-- 1248 FGISP EALAMDPQQRLLLE SWEA E AGIDP LRGS TGVF G+ Y Sbjct: 2786 LFGISPREALAMDPQQRLLLELSWEAFERAGIDPTGLRGSDTGVFAGVMYHDYAHAAEAL 2845 Query: 1249 -QAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLAL 1307 + + Y TG SV SGRI+Y GL GPA++VDTACSSSLVALHLAA SLRAGEC +A+ Sbjct: 2846 PETEGYRATGGAGSVVSGRIAYTYGLEGPAVTVDTACSSSLVALHLAARSLRAGECSMAV 2905 Query: 1308 AGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQ 1367 GG TV++ P +F+ FS+QRGLA DGRCK+F+ ADGTG+SEGAG+L+++RLSDARR G Sbjct: 2906 VGGVTVMSAPGVFVDFSKQRGLAPDGRCKSFSADADGTGWSEGAGVLLVERLSDARRHGH 2965 Query: 1368 PVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGD 1427 VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AAL+DAG+ DVD+VEAHGTGT+LGD Sbjct: 2966 DVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALADAGLAPGDVDMVEAHGTGTKLGD 3025 Query: 1428 PIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHI 1487 P+EA+ALLATYG+ + PLWLGS+KSN+GH+QAAAGV G+IK V A+RH +LP TLH Sbjct: 3026 PVEAEALLATYGQVRDAERPLWLGSLKSNIGHTQAAAGVGGIIKTVLALRHGVLPRTLHA 3085 Query: 1488 DQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXX 1547 D+PS+HVDWS G V+LLT+ REWP+ VGRPRRA VSSFG+SGTNAH Sbjct: 3086 DEPSSHVDWSAGAVELLTDEREWPS-VGRPRRAAVSSFGISGTNAHTVIEQAPDEPEPAP 3144 Query: 1548 XXXG--PGVLA-WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 P L WV+S + G+ AQA RL E A + D+G +L T R+ EHRA Sbjct: 3145 RRETRVPDTLVPWVLSGASPEGLRAQAARLRETAAAE---EPADIGLALATRRAALEHRA 3201 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VV+G GR+ELL L + GR SGVA P G+T F+F GQG+Q LGMGREL +P Sbjct: 3202 VVLGTGREELLRELDALAAGRG--NAPSGVASP-GRTGFLFTGQGSQRLGMGRELYGAFP 3258 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 +D L RPLREVV+G DA LL T +AQ LFA+EVAL+RL+ESWG+ Sbjct: 3259 VFADAFDAVCARVD--LERPLREVVFGEDAGLLERTVYAQAGLFALEVALFRLVESWGVA 3316 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P +++GHSVGE++AAHV+G RGRLM ALP GG M AV+A E++L L Sbjct: 3317 PDVLVGHSVGEIAAAHVAGVLSLDDACALVSARGRLMDALPEGGAMLAVEAAEEDLE--L 3374 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 + V +AAVNGP SV +SG AV+ + +RL AQG RV+RLAVSHAFHS LMEPML +F Sbjct: 3375 PDGVELAAVNGPTSVTVSGEAAAVAGLEERLRAQGVRVKRLAVSHAFHSRLMEPMLAEFA 3434 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 V + P IPV + G D + +YWV +RE VRFAD+V AH AGATRF+ Sbjct: 3435 EVVRSLTYHAPRIPVDTTAPG-----DPATPEYWVGQVREPVRFADAVRRAHEAGATRFL 3489 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 E+GP G L++L+ V+ AVP LR E W L Sbjct: 3490 ELGPDGPLSALVAHLTEDVA--AVPALRSGHDEHTTLLRGVAEMYAHGADIAWDRYLEPL 3547 Query: 1965 GGQRVGLPTYAFAHERFW 1982 GG V LPTYAF R+W Sbjct: 3548 GGHAVELPTYAFQRRRYW 3565 Score = 826 bits (2134), Expect = 0.0 Identities = 482/980 (49%), Positives = 597/980 (60%), Gaps = 42/980 (4%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL + E++ +V A VLG AA + +AF D G SL+AVELRN L+ Sbjct: 4161 RLAAAGEGERRRITEELVRTLAAFVLGHGTAATVAPDKAFRDLGFDSLTAVELRNALRAA 4220 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRI---DEPIAIVGMGCR 1126 TG+ L A FD+PTP LA L + L +A A R ++P+A+V MGCR Sbjct: 4221 TGLPLPAGLIFDHPTPAALATRLRAELTGGAGTATATPAPGRPAPPAPEDPVAVVAMGCR 4280 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 +PG ++P + W L++ G D++G+FP DRGWD+ D + R GGF+ D A Sbjct: 4281 FPGA-ATPEEFWDLLSRGLDLVGDFPADRGWDLRDAPD---------FARRGGFLPDAAG 4330 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG-- 1244 FD FG+SP EA AMDPQQRL+LE SWE E AG+DP +L+GS GVFVG G Y Sbjct: 4331 FDADLFGVSPREAQAMDPQQRLMLEISWETFERAGVDPASLQGSRVGVFVGTNGQDYAGL 4390 Query: 1245 --LGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGE 1302 S + + TG SV SGRISY GL GPA++VDTACSSSLVALHLAA SLR+GE Sbjct: 4391 FPATGSGLEGHVATGSAASVLSGRISYTYGLEGPAVTVDTACSSSLVALHLAAQSLRSGE 4450 Query: 1303 CDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDA 1362 C +ALAGG TV+A P+ F+ F+ QRGLA DGRCKAF+ ADGTG+ EGAG+++L+RLSDA Sbjct: 4451 CSMALAGGVTVMAAPTAFLEFAHQRGLAADGRCKAFSADADGTGWGEGAGLVLLERLSDA 4510 Query: 1363 RRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTG 1422 R G VL +L GSAVNQDGASNGLTAP+GPAQQRVI AAL+ AG+ ++VD VEAHGTG Sbjct: 4511 RAQGHRVLGLLRGSAVNQDGASNGLTAPNGPAQQRVIRAALNSAGLWPSEVDAVEAHGTG 4570 Query: 1423 TRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLP 1482 TRLGDPIEA+ALLATYGRD + PL+LGS+KSN+GH+QAAAG+AGVIKM+ AM H LP Sbjct: 4571 TRLGDPIEAEALLATYGRDRS--EPLYLGSVKSNIGHTQAAAGIAGVIKMLLAMDHGELP 4628 Query: 1483 ATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXX 1542 TLH PS VDW G++ LLTE W V RPRRA VSSFG+SGTNAH Sbjct: 4629 RTLHAAAPSPSVDWDSGSLSLLTETTPWTPRVDRPRRAAVSSFGISGTNAHVVLEQADVA 4688 Query: 1543 XXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEH 1602 VL W SA + A + A+A LL + + G +L TT H Sbjct: 4689 VPSAPAQ--DSVLPWAFSAHSGAALNARAKGLL-VLCDDPGVSGVAAGRALATTGLGLAH 4745 Query: 1603 RAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAG 1662 RAVV+ GL + P G A G T +F GQG+Q GMGR+L Sbjct: 4746 RAVVLAEDIAGYAEGLTALTTDEPSARAVRGTARE-GSTALLFSGQGSQRSGMGRDLYEA 4804 Query: 1663 YPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWG 1722 +P +D L RPLREVV+G DA LL T +AQ LFA+EVAL+RL+ESWG Sbjct: 4805 FPVFADAFDAVCARVD--LERPLREVVFGEDAGLLERTVYAQAGLFALEVALFRLVESWG 4862 Query: 1723 MRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRP 1782 + P +++GHS+GEL+AAHV+G RGRLM ALP GG M AV+ E+ L Sbjct: 4863 VTPDVLVGHSIGELAAAHVAGVLSLDDACALVSARGRLMDALPEGGAMLAVEVAEEALEL 4922 Query: 1783 LLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQ 1842 L G V +AAVNGP SV +SG EA++ + +RL AQ RV+RLAVSHAFHS LMEPML Sbjct: 4923 LDG--VDLAAVNGPTSVTVSGEAEAIAELEERLRAQEVRVKRLAVSHAFHSRLMEPMLAD 4980 Query: 1843 FRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATR 1902 F AVA + P IPV++ G D + +YWV +RE VRFAD++ AH AGATR Sbjct: 4981 FAAVARSLTYHAPQIPVLTTAPG-----DLATPEYWVGQVREPVRFADALGRAHEAGATR 5035 Query: 1903 FVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLA 1962 F+E+GP G L+ L+ AVP +R+ RPE D A+V Sbjct: 5036 FLELGPDGVLSGLVPG--------AVPAMRRRRPEVEALFAAVARLWVEGMAVDLAAVFP 5087 Query: 1963 GCGGQRVGLPTYAFAHERFW 1982 V LP Y F H RFW Sbjct: 5088 --EAPPVTLPPYPFQHTRFW 5105 Score = 676 bits (1743), Expect = 0.0 Identities = 424/987 (42%), Positives = 560/987 (56%), Gaps = 42/987 (4%) Query: 2 TDGLHSAD------ALQEWFTHYIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELS 54 TDGL + A++E +AA G S V+ +DLG S+ + + L+ Sbjct: 2603 TDGLAALPEPERTRAVEELVRTTVAAVLGHSSGTGVDTGRTFKDLGFDSLTGVELRNRLA 2662 Query: 55 DVLGICVPDLAVWDNPSAHDVIKSV---LGGDGSQRSADSDTGCAVLGNGPTNEPIAVIG 111 G+ + V+ +PS + + L G + + A +EPIAV+ Sbjct: 2663 AATGLRLAATLVFSHPSPAALTAHLCEELSGTAADAAVPRSRKSAA-----ADEPIAVVA 2717 Query: 112 MACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE--TIY---GCFLE 166 M+CR+ G V G LW + E + IT +P R A D T Y G FL Sbjct: 2718 MSCRYPGGVDGPEELWRMVREGRDGITGFPTDRGWDLARLHDPDPSRPGTTYARHGGFLH 2777 Query: 167 DVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTD 226 D FD + F I P EA MDPQQRLLLE SW A E AGI P L+ S TGVF GV D Sbjct: 2778 DAADFDAELFGISPREALAMDPQQRLLLELSWEAFERAGIDPTGLRGSDTGVFAGVMYHD 2837 Query: 227 YVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSL 286 Y + + TGG+ S+++ R++Y + GP++ +DTACSSSLVA HLA +SL Sbjct: 2838 YAHAA-EALPETEGYRATGGAGSVVSGRIAYTYGLEGPAVTVDTACSSSLVALHLAARSL 2896 Query: 287 ASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLER 346 +GEC +AVV G V+ +P V+ F + ++P G C++F A ADG EG GV+++ER Sbjct: 2897 RAGECSMAVVGGVTVMSAPGVFVDFSKQRGLAPDGRCKSFSADADGTGWSEGAGVLLVER 2956 Query: 347 LSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEA 406 LSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + P ++D VEA Sbjct: 2957 LSDARRHGHDVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALADAGLAPGDVDMVEA 3016 Query: 407 HGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQR 466 HGTGT +GD +EA AL +G+ R A +PL +GS+K NIGH + AAG+ G+IKTVL L+ Sbjct: 3017 HGTGTKLGDPVEAEALLATYGQVRDAERPLWLGSLKSNIGHTQAAAGVGGIIKTVLALRH 3076 Query: 467 GQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXX 526 G L + + P+ ++ ++ + ++ + +EWP+ VGRPRRA VSSFG GTNAH Sbjct: 3077 GVLPRTLHADEPSSHVDWSAGAVELLTDEREWPS-VGRPRRAAVSSFGISGTNAHTVIEQ 3135 Query: 527 XXXXXXXXXXXXG--PGVLA-WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVT 583 P L WV+S + G+ AQA RL E A + D+G +L T Sbjct: 3136 APDEPEPAPRRETRVPDTLVPWVLSGASPEGLRAQAARLRETAAAE---EPADIGLALAT 3192 Query: 584 TRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGM 643 R+ EHRAVV+G GR+ELL L + GR SGVA P G+T F+F GQG+Q LGM Sbjct: 3193 RRAALEHRAVVLGTGREELLRELDALAAGRG--NAPSGVASP-GRTGFLFTGQGSQRLGM 3249 Query: 644 GRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALY 703 GREL +P +D L RPLREVV+G DA LL T +AQ LFA+EVAL+ Sbjct: 3250 GRELYGAFPVFADAFDAVCARVD--LERPLREVVFGEDAGLLERTVYAQAGLFALEVALF 3307 Query: 704 RLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQA 763 RL+ESWG+ P +++GHSVGE++AAHV+G RGRLM ALP GG M AV+A Sbjct: 3308 RLVESWGVAPDVLVGHSVGEIAAAHVAGVLSLDDACALVSARGRLMDALPEGGAMLAVEA 3367 Query: 764 GEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVL 823 E++L L + V +AAVNGP SV +SG AV+ + +RL AQG RV+RLAVSHAFHS L Sbjct: 3368 AEEDLE--LPDGVELAAVNGPTSVTVSGEAAAVAGLEERLRAQGVRVKRLAVSHAFHSRL 3425 Query: 824 MEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFA 883 MEPML +F V + P IPV + G D + +YWV +RE VRFAD+V A Sbjct: 3426 MEPMLAEFAEVVRSLTYHAPRIPVDTTAPG-----DPATPEYWVGQVREPVRFADAVRRA 3480 Query: 884 HSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXX 943 H AGATRF+E+GP G L++L+ V+ AVP LR E Sbjct: 3481 HEAGATRFLELGPDGPLSALVAHLTEDVA--AVPALRSGHDEHTTLLRGVAEMYAHGADI 3538 Query: 944 DWASVLAGCGGQRVGLPTYAFAHERFW 970 W L GG V LPTYAF R+W Sbjct: 3539 AWDRYLEPLGGHAVELPTYAFQRRRYW 3565 Score = 640 bits (1650), Expect = 0.0 Identities = 391/943 (41%), Positives = 534/943 (56%), Gaps = 18/943 (1%) Query: 29 EVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGGDGSQRS 88 EV+ + + LG+ S+ ++ + L+ G+ +P ++D+P+ + + + + Sbjct: 947 EVDPEQTFKALGIASLTLVELRTRLATATGLSLPPTFLFDHPTPAAAARHLCDALRGEDA 1006 Query: 89 ADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAA 148 A ++P+ ++ MACRF G + LW+ L+E + +T P R Sbjct: 1007 ARPSRAMPAPQPADADDPVVIVSMACRFPGGIDSPAALWEALSEGREVLTGLPEDRGWQP 1066 Query: 149 AADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILP 208 A L T G FL+D+ GFD F I P EA MDPQQRLLLE +W ALE G P Sbjct: 1067 ALAALETPLPTAGG-FLDDIAGFDAALFGISPREAVAMDPQQRLLLEVTWEALERLGTDP 1125 Query: 209 KTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVI 268 L+ S TGVFVG ++ DY + + TG ++S+ + R++Y ++GP++ + Sbjct: 1126 TDLRGSRTGVFVGATAQDYGPRMHEPAESSEGYLLTGTTASVASGRIAYAFALDGPAVTV 1185 Query: 269 DTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDA 328 DTACSSSLVA HLA +SL +GEC A+ G ++ +P V F +SP G C+AF A Sbjct: 1186 DTACSSSLVALHLAAQSLRAGECSTALAGGVTLMATPGVLVEFARQDGLSPDGRCKAFGA 1245 Query: 329 RADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLD 388 RADG EG G++VL RLSDA G+ VLAVL GSAVN DG SNG+ APN AQ V+ Sbjct: 1246 RADGTGWSEGAGMLVLRRLSDALADGQHVLAVLRGSAVNSDGASNGLTAPNGLAQRRVIR 1305 Query: 389 SACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHL 448 +A A + P+++D VEAHGTGT +GD IEA AL +G+ R A +PL +GS+K NIGH Sbjct: 1306 AALDAAGLRPSDVDMVEAHGTGTRLGDPIEAQALLATYGQERDAERPLWLGSLKSNIGHT 1365 Query: 449 EGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRA 508 + AAG+AG+IKTVL L+ G L + + P P++ ++ + ++ E P RP RA Sbjct: 1366 QSAAGVAGVIKTVLALRHGVLPRTLHADEPTPHVDWSAGAVRLLTENVTLPP-ADRPYRA 1424 Query: 509 GVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGV-LAWVVSARTAAGVGAQAGRLLEFVR 567 GVSSFG GTNAH GP + L ++S AA + QA RL F+ Sbjct: 1425 GVSSFGISGTNAHAVIEAAPEPAVPDEGTPGPRLALPVLLSGHGAAALRDQAARLRAFLD 1484 Query: 568 AGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGG 627 A + + S TTR +HRA + A R+EL A L V EG GV GVA P G Sbjct: 1485 AEPSVPPTAIARSSATTRFPLDHRAALFAADREELAARLDAVAEGHDAAGVLHGVASP-G 1543 Query: 628 KTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNT 687 +T F+F GQG+Q LGMGREL +P +D L RPLR VV+G DA LL Sbjct: 1544 RTGFLFTGQGSQRLGMGRELYGAFPVFADAFDAVCARVD--LERPLRGVVFGEDAGLLER 1601 Query: 688 TEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGR 747 T +AQ LFA+EVAL+RL+ESWG+ P +++GHS+GEL+AAH +G RGR Sbjct: 1602 TVYAQAGLFALEVALFRLVESWGVVPDVLVGHSIGELAAAHCAGVLSLEDACALVSARGR 1661 Query: 748 LMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQG 807 LM ALP GG M AV+ E ELR L + V +AAVNGP SV +SG +AV+ + +RL A+ Sbjct: 1662 LMDALPAGGAMLAVEVAEGELR--LPDGVDLAAVNGPTSVTVSGEADAVAGLEERLRARE 1719 Query: 808 RRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWV 867 RV+RLAVSHAFHS LMEPML F AVA+ + P IPV + G + + +YWV Sbjct: 1720 IRVKRLAVSHAFHSRLMEPMLADFAAVAESLTYHAPQIPVRTTAPGAI-----DTPEYWV 1774 Query: 868 RHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPF 927 IRE VRFAD++ A F+E+GP G L++L+ LA+ VAVP LR+ + + Sbjct: 1775 GQIREPVRFADAL--ASLPEVRTFLELGPDGVLSALVPVLLAE--AVAVPLLRRGQ-DGT 1829 Query: 928 XXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 DW +V + V LP+YAF R+W Sbjct: 1830 RPAHAAAVLWTRGVPLDWTAVTGTGTSRPVELPSYAFQRTRYW 1872 Score = 622 bits (1605), Expect = e-175 Identities = 394/950 (41%), Positives = 519/950 (54%), Gaps = 41/950 (4%) Query: 27 SAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPS----AHDVIKSVLGG 82 +A V D RDLG S+ + + L G+ +P ++D+P+ A + + GG Sbjct: 4191 AATVAPDKAFRDLGFDSLTAVELRNALRAATGLPLPAGLIFDHPTPAALATRLRAELTGG 4250 Query: 83 DGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPA 142 G+ + + A +P+AV+ M CRF G WD L+ + ++PA Sbjct: 4251 AGTATATPAPGRPAPPA---PEDPVAVVAMGCRFPGAATPE-EFWDLLSRGLDLVGDFPA 4306 Query: 143 RRLGAAAADW-LGDEQETIY-GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAA 200 R W L D + G FL D GFD F + P EA MDPQQRL+LE SW Sbjct: 4307 DR------GWDLRDAPDFARRGGFLPDAAGFDADLFGVSPREAQAMDPQQRLMLEISWET 4360 Query: 201 LEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLD 260 E AG+ P +L+ S GVFVG + DY L G TG ++S+++ R+SY Sbjct: 4361 FERAGVDPASLQGSRVGVFVGTNGQDYAGLFPATGSGLEGHVATGSAASVLSGRISYTYG 4420 Query: 261 VNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPT 320 + GP++ +DTACSSSLVA HLA +SL SGEC +A+ G V+ +P + F ++ Sbjct: 4421 LEGPAVTVDTACSSSLVALHLAAQSLRSGECSMALAGGVTVMAAPTAFLEFAHQRGLAAD 4480 Query: 321 GSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNP 380 G C+AF A ADG GEG G+V+LERLSDAR G VL +L GSAVNQDG SNG+ APN Sbjct: 4481 GRCKAFSADADGTGWGEGAGLVLLERLSDARAQGHRVLGLLRGSAVNQDGASNGLTAPNG 4540 Query: 381 RAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGS 440 AQ V+ +A A + P+E+D VEAHGTGT +GD IEA AL +GR R ++PL +GS Sbjct: 4541 PAQQRVIRAALNSAGLWPSEVDAVEAHGTGTRLGDPIEAEALLATYGRDR--SEPLYLGS 4598 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPA 500 +K NIGH + AAGIAG+IK +L + G+L + P+P++ + L+++ E W Sbjct: 4599 VKSNIGHTQAAAGIAGVIKMLLAMDHGELPRTLHAAAPSPSVDWDSGSLSLLTETTPWTP 4658 Query: 501 VVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAG 560 V RPRRA VSSFG GTNAH VL W SA + A + A+A Sbjct: 4659 RVDRPRRAAVSSFGISGTNAHVVLEQADVAVPSAPAQ--DSVLPWAFSAHSGAALNARAK 4716 Query: 561 RLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVAS 620 LL + + G +L TT HRAVV+ GL + P Sbjct: 4717 GLL-VLCDDPGVSGVAAGRALATTGLGLAHRAVVLAEDIAGYAEGLTALTTDEPSARAVR 4775 Query: 621 GVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA 680 G A G T +F GQG+Q GMGR+L +P +D L RPLREVV+G Sbjct: 4776 GTARE-GSTALLFSGQGSQRSGMGRDLYEAFPVFADAFDAVCARVD--LERPLREVVFGE 4832 Query: 681 DAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXX 740 DA LL T +AQ LFA+EVAL+RL+ESWG+ P +++GHS+GEL+AAHV+G Sbjct: 4833 DAGLLERTVYAQAGLFALEVALFRLVESWGVTPDVLVGHSIGELAAAHVAGVLSLDDACA 4892 Query: 741 XXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVV 800 RGRLM ALP GG M AV+ E+ L L G V +AAVNGP SV +SG EA++ + Sbjct: 4893 LVSARGRLMDALPEGGAMLAVEVAEEALELLDG--VDLAAVNGPTSVTVSGEAEAIAELE 4950 Query: 801 DRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDY 860 +RL AQ RV+RLAVSHAFHS LMEPML F AVA + P IPV++ G D Sbjct: 4951 ERLRAQEVRVKRLAVSHAFHSRLMEPMLADFAAVARSLTYHAPQIPVLTTAPG-----DL 5005 Query: 861 GSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLR 920 + +YWV +RE VRFAD++ AH AGATRF+E+GP G L+ L+ AVP +R Sbjct: 5006 ATPEYWVGQVREPVRFADALGRAHEAGATRFLELGPDGVLSGLVPG--------AVPAMR 5057 Query: 921 KDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 + RPE D A+V V LP Y F H RFW Sbjct: 5058 RRRPEVEALFAAVARLWVEGMAVDLAAVFP--EAPPVTLPPYPFQHTRFW 5105 Score = 513 bits (1321), Expect = e-142 Identities = 382/1083 (35%), Positives = 516/1083 (47%), Gaps = 59/1083 (5%) Query: 1116 EPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYT 1175 E AI+G CR PG PA LW+L+A+G D I E P DR A + T Sbjct: 10 EAFAIIGYACRLPGA-PGPAPLWELLATGTDAITEIPSDR-------------ARVPSVT 55 Query: 1176 RHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVF 1235 R GGF+ ADFD GFFG+SP EA A DPQQRL LE +WEALEDA P L GS TGVF Sbjct: 56 R-GGFIERAADFDAGFFGMSPREAAATDPQQRLALELAWEALEDARHLPAGLGGSRTGVF 114 Query: 1236 VGIYGDGYGL-----GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVA 1290 +G D Y G + ++ G + + R+SY LGL GP+++VD SSSLV+ Sbjct: 115 LGAIWDDYAALLHRAGDAGIDRHSMPGLQRGLIANRLSYTLGLHGPSLTVDAGQSSSLVS 174 Query: 1291 LHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEG 1350 +HLA SL GE +LALAGG ++ P + R GL+ DGRC F A+G EG Sbjct: 175 VHLACESLARGESELALAGGVNLVLAPDSTVSALRFGGLSPDGRCFTFDARANGFVRGEG 234 Query: 1351 AGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITG 1410 G++VL+ L+ A G + A++ GSAVN DG LT PS AQ+ V+ AA + AGI Sbjct: 235 GGVVVLKPLARALTDGDRIHAVVRGSAVNNDGGGPSLTTPSAAAQEAVLRAAHARAGIAP 294 Query: 1411 ADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVI 1470 V VE HGTGT +GDP+EA AL A G T APL +GS+K+N+GH + AAG+AG++ Sbjct: 295 DAVGYVELHGTGTPVGDPVEAAALGAALGTART--APLPVGSVKTNIGHLEGAAGIAGLL 352 Query: 1471 KMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGT 1530 K + ++P +L+ P A + +++ T A +G GVSSFG+ GT Sbjct: 353 KAALVVERGVVPPSLNFASPPAGIPLERLNLRVQTAA----GPLGGEGFVGVSSFGMGGT 408 Query: 1531 NAHXXXXXXXXXXXXXXXXX--------GPGV------LAWVVSARTAAGVGAQAGRLLE 1576 N H PG + +VS TA + AQA RL + Sbjct: 409 NCHLVLGPAPDPVARPAAEPPAHAAVPPAPGSDRTTPPVPVLVSGHTAQALRAQAARLKD 468 Query: 1577 FVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAM 1636 V G +L DV +SL TTR+ F RAV++ R++LLA L+ V G P GV+ G A Sbjct: 469 AVE-GADLAVADVAHSLATTRTRFARRAVLLAEDREQLLAQLSAVAAGLPATGVSEGAAR 527 Query: 1637 PGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGAD-AE 1695 G + +F GQG+QW M L L H L +V+ GA+ A Sbjct: 528 TG-RLAMIFSGQGSQWPAMATGLLDTDEVFTRAIHACAEALAPHTDFSLTDVLRGAEGAP 586 Query: 1696 LLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXX 1755 L + QPALFAV VAL S G+ P V GHS GE++AA V+G Sbjct: 587 TLERVDVVQPALFAVMVALAETWRSLGVVPDAVAGHSQGEIAAACVAGALSLPDAAKVVA 646 Query: 1756 MRGRLMQALPGGGVMYAVQAGEQELRPLL--GEQVSVAAVNGPGSVVLSGAREAVSVVVD 1813 +R R + AL G G M +VQAG +RP L +S+AA NGP +VV+SG +A+ Sbjct: 647 LRSRAIGALAGQGGMLSVQAGAARVRPWLETAPALSIAADNGPTAVVVSGPVDALDGFAA 706 Query: 1814 RLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYG 1873 R G RR+ V +A HS +E + ++ ++ +P +S VTG+ Sbjct: 707 RCVTYGVETRRIPVDYASHSAHVELIHDELLTALADIEPRTSEVPFLSTVTGEWTDTAGL 766 Query: 1874 SADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV---VAVPT 1930 A YW R++R V F+ +V VE P L + + + LA++ V + Sbjct: 767 DAAYWYRNLRSTVEFSAAVRRLADEDFRFIVEATPHPVLVAAVRDILAELDAPDTAVVGS 826 Query: 1931 LRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL-ADRFXX 1989 LR R E D L G V LPTYAF ER W + Sbjct: 827 LR--RGEGGRARLLGSAAELLAHGRDVR--LPAPPGTVVDLPTYAFQRERHWRPGEAAAL 882 Query: 1990 XXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGR 2049 RL+ LS + V ++ H A V G Sbjct: 883 WDGTGEPVRDAAAPDTGADPDTAAVPDDSLRDRLRALSPQSARGTVRELIRSHAAVVGGF 942 Query: 2050 DGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLH 2109 A ++D Q F G+ SL+ VELR RL T TG++L T FD+PTP A HL L Sbjct: 943 AAAEEVDPEQTFKALGIASLTLVELRTRLATATGLSLPPTFLFDHPTPAAAARHLCDALR 1002 Query: 2110 HQN---PTGATPELDRVDALTDLFLQTCDA---GRDDDGWQIVALAANGRERMTTPVPKR 2163 ++ P+ A P DA + + + G D + + GRE +T R Sbjct: 1003 GEDAARPSRAMPAPQPADADDPVVIVSMACRFPGGIDSPAALWEALSEGREVLTGLPEDR 1062 Query: 2164 EWK 2166 W+ Sbjct: 1063 GWQ 1065 Score = 77.8 bits (190), Expect = 2e-11 Identities = 46/108 (42%), Positives = 60/108 (55%), Gaps = 1/108 (0%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL G AEQ+ ++ +V TAAVLG A +D + F D G S++AVELRN L Sbjct: 5596 RLAGAPQAEQERILVDLVVSRTAAVLGHGTPAAIDPDRQFRDLGTDSVTAVELRNLLDVA 5655 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL-HHQNRSAPAAAVRTRVRIDE 1116 TG TL AT FD+PTP LA HL L ++APA R+++ Sbjct: 5656 TGRTLPATLVFDHPTPAALATHLRGLLVSGPGQAAPAGGESAVARLEK 5703 Score = 76.3 bits (186), Expect = 5e-11 Identities = 41/83 (49%), Positives = 50/83 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL G AEQ+ ++ +V TAAVLG A +D + F D G S++AVELRN L Sbjct: 5596 RLAGAPQAEQERILVDLVVSRTAAVLGHGTPAAIDPDRQFRDLGTDSVTAVELRNLLDVA 5655 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 TG TL AT FD+PTP LA HL Sbjct: 5656 TGRTLPATLVFDHPTPAALATHL 5678 Score = 71.2 bits (173), Expect = 2e-09 Identities = 50/148 (33%), Positives = 67/148 (45%), Gaps = 6/148 (4%) Query: 2023 LQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLT 2082 L L + E+ AV +V AAVLG +D G+ F D G SL+ VELRNRL T Sbjct: 2606 LAALPEPERTRAVEELVRTTVAAVLGHSSGTGVDTGRTFKDLGFDSLTGVELRNRLAAAT 2665 Query: 2083 GVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTD----LFLQTCD-AG 2137 G+ L+AT F +P+P L HL L A P R A D + +C G Sbjct: 2666 GLRLAATLVFSHPSPAALTAHLCEELSGTAADAAVPR-SRKSAAADEPIAVVAMSCRYPG 2724 Query: 2138 RDDDGWQIVALAANGRERMTTPVPKREW 2165 D ++ + GR+ +T R W Sbjct: 2725 GVDGPEELWRMVREGRDGITGFPTDRGW 2752 Score = 61.2 bits (147), Expect = 2e-06 Identities = 36/87 (41%), Positives = 47/87 (54%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL + E++ +V A VLG AA + +AF D G SL+AVELRN L+ Sbjct: 4161 RLAAAGEGERRRITEELVRTLAAFVLGHGTAATVAPDKAFRDLGFDSLTAVELRNALRAA 4220 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L A FD+PTP LA L + L Sbjct: 4221 TGLPLPAGLIFDHPTPAALATRLRAEL 4247 >tr|A0QFF5|A0QFF5_MYCA1 Tax_Id=243243 SubName: Full=Erythronolide synthase, modules 3 and 4; EC=2.3.1.94;[Mycobacterium avium] Length = 4171 Score = 1170 bits (3026), Expect = 0.0 Identities = 607/976 (62%), Positives = 711/976 (72%), Gaps = 9/976 (0%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG A +D +AF + G SL+AVE+RNRLKT Sbjct: 1964 RLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTA 2023 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TG+ LS T FDYPTP LA ++ + L + A V R D+PIAIVGM CR+PG Sbjct: 2024 TGLALSPTLIFDYPTPNALAGYIRTELAGAPQETTHAPV-VRATDDDPIAIVGMSCRFPG 2082 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV SP LWQ+VA G DV+ EFP DRGWD+ +++PDPD G YTR GGFV +VADFDP Sbjct: 2083 GVDSPEALWQMVAEGRDVLSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFDP 2142 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ 1249 FFGI+P EALAMDPQQR+ LE SWEALE AGIDP LRGS+TG+F G+Y GYG+G + Sbjct: 2143 AFFGIAPSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGVYTQGYGMGAAP 2202 Query: 1250 -AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALA 1308 A+ + TG +SVASGR+SY LGL GPA+SVDTACSSSLVALH+A SLR+GECDLALA Sbjct: 2203 IAEGFRLTGQSSSVASGRVSYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALA 2262 Query: 1309 GGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQP 1368 GG TV ATP IF+ FSR RGL+ DGRCKA+A AADGTGFSEG GMLV++RLSDARR G P Sbjct: 2263 GGVTVNATPDIFVEFSRMRGLSVDGRCKAYAGAADGTGFSEGGGMLVVERLSDARRLGHP 2322 Query: 1369 VLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDP 1428 VLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT LGDP Sbjct: 2323 VLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDP 2382 Query: 1429 IEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHID 1488 IEAQALLATYG+D PLWLGSIKSNMGH+QAAAGVAGVIKMV AMRH+LLPATLH+D Sbjct: 2383 IEAQALLATYGQDR--GQPLWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVD 2440 Query: 1489 QPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXX 1548 +PS HVDWS G V LLTEA+ WP RPRRAGVSSFG+SGTNAH Sbjct: 2441 EPSPHVDWSAGAVSLLTEAQPWPGE--RPRRAGVSSFGISGTNAHVIIEAVPAVEPAHAD 2498 Query: 1549 XXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVG 1608 VL WVVSA++AA + AQA RL E+VRA ELD DVG++L R+ FEHRAVVVG Sbjct: 2499 APALPVLPWVVSAKSAAALRAQAARLAEYVRAQGELDIADVGWTLAG-RATFEHRAVVVG 2557 Query: 1609 AGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXX 1668 RD LLAGL E+ P + GVA P GKTVFVFPGQG+Q LGMGR+L AGYP Sbjct: 2558 GDRDRLLAGLDELAADDPAASIIRGVATPAGKTVFVFPGQGSQTLGMGRQLHAGYPVFAE 2617 Query: 1669 XXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLV 1728 ELDRHL RPLR+V+WG D +LN+TEFAQPALFAVEVAL+RLLESWG+RP V Sbjct: 2618 AFDAVVAELDRHLLRPLRDVIWGDDENVLNSTEFAQPALFAVEVALFRLLESWGVRPDFV 2677 Query: 1729 MGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQV 1788 MGHS+GELSAAHV+G RGR MQALP GG M AVQA E ++RPLLG V Sbjct: 2678 MGHSIGELSAAHVAGVLSLQNAAVLVAARGRFMQALPEGGAMIAVQATEAQVRPLLGPDV 2737 Query: 1789 SVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVAD 1848 +AAVNGP +VV+SG +A + +RL A+G RV RL+VSHAFHS LMEPM+++F VA Sbjct: 2738 GIAAVNGPAAVVISGDHDAAVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTVAA 2797 Query: 1849 EVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGP 1908 + +P IP+ISN+TGQ A+D+GS +YW H+R+AVRFADSV FA SAGATRF+EVGP Sbjct: 2798 GLAIDKPVIPIISNLTGQPAADDFGSPEYWKCHVRDAVRFADSVRFAQSAGATRFLEVGP 2857 Query: 1909 AGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQR 1968 + GLT+ IEE+LA VV V LRKDRPEP DW L G Sbjct: 2858 SSGLTAAIEETLADAPVVTVSALRKDRPEPVALVNAVAQGWVCGMDVDWRGALG--TGHL 2915 Query: 1969 VGLPTYAFAHERFWLA 1984 V LPTYAF RFWL+ Sbjct: 2916 VDLPTYAFDRRRFWLS 2931 Score = 864 bits (2232), Expect = 0.0 Identities = 476/881 (54%), Positives = 575/881 (65%), Gaps = 16/881 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA G DVI EFP DRGWD+ L+DPDPDA K Sbjct: 33 RSSEPIAIVGMSCRFPGGVDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHK 92 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 Y GGFV +VADFDP FFGI+P EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 93 CYVNTGGFVDNVADFDPAFFGIAPSEALAMDPQHRMLLELSWEALERAGIDPSGLRGSAT 152 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR+SY LGL GPA+SVDTACSSSLVALH Sbjct: 153 GVFAGLIVQGYGMLAEEIEGYRLTGMTSSVASGRVSYVLGLEGPAVSVDTACSSSLVALH 212 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG+TV ATP++F+ FSR RGLA DGRCKA+A AADG G+SEG Sbjct: 213 MAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRCKAYAGAADGVGWSEGGA 272 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLV++RLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 273 MLVVERLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 332 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKM 1472 VDVVE HGTGT LGDPIEAQALLATYG+D PLWLGSIKSNMGH+QAAAGVAGVIKM Sbjct: 333 VDVVEGHGTGTTLGDPIEAQALLATYGQDR--GQPLWLGSIKSNMGHTQAAAGVAGVIKM 390 Query: 1473 VEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNA 1532 V AMRH+LLPATLH+D+PS HVDWS G V LLTEA+ WP RPRRAGVSSFG+SGTNA Sbjct: 391 VLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWPG--ERPRRAGVSSFGISGTNA 448 Query: 1533 HXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYS 1592 H VL WVVSA++AA + AQA RL E+VRA ELD DVG++ Sbjct: 449 HVIIEAVPAVEPAHADAPALPVLPWVVSAKSAAALRAQAARLAEYVRAQGELDIADVGWT 508 Query: 1593 LVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQW 1652 L R+ FEHRAVVVG RD LLAGL E+ P + GVA P GKTVFVFPGQG+QW Sbjct: 509 L-AGRATFEHRAVVVGGDRDRLLAGLDELAADDPAASIIRGVATPAGKTVFVFPGQGSQW 567 Query: 1653 LGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAVE 1711 LGM EL P + L + + GA A ++ + QPALFAV Sbjct: 568 LGMATELLDTAPVFAQHIQACEEAFAEFVDWSLIDALRGAPGAAGMDRVDVVQPALFAVM 627 Query: 1712 VALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMY 1771 V+L L +S G+ P V+GHS GE++AA+V+G +R +L+++L G G M Sbjct: 628 VSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLRSLAGPGGML 687 Query: 1772 AVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVS 1828 ++ + R LL G +VS+AAVNG +VV+SG A+ + A R RR+ V Sbjct: 688 SIACSTERARELLAPYGNRVSIAAVNGRSAVVVSGEGAALDELAAFCADLALRTRRIDVD 747 Query: 1829 HAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRF 1888 +A HSV +E + E + I S VTG + ADYW R+IR+ V+F Sbjct: 748 YASHSVEVEAIREDLAQALTGIEPRSSRIAFFSTVTGNRLDTAGLDADYWYRNIRQTVQF 807 Query: 1889 ADSVCFAHSAGATRFVEVGPAGGLTSLIEESL-----AQVSVVAVPTLRKDRPEPFXXXX 1943 +V A G F+E P L + IE+++ + +PTL +D Sbjct: 808 DQTVRSAAEHGYRTFIESSPHPALVAGIEDTVNDSLPGDTEAIVIPTLGRDDGGLERFLT 867 Query: 1944 XXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 W VL G G V LPTYAF RFWL+ Sbjct: 868 SAATAFVAGVNVAWRGVLDGAG--FVELPTYAFDRRRFWLS 906 Score = 830 bits (2143), Expect = 0.0 Identities = 475/983 (48%), Positives = 611/983 (62%), Gaps = 30/983 (3%) Query: 3 DGLHSAD---ALQEWFTHYIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLG 58 DGL A+ L E +IA G +AE ++ D ++LG S+ + + L G Sbjct: 1966 DGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTATG 2025 Query: 59 ICVPDLAVWDNPSAHDV---IKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACR 115 + + ++D P+ + + I++ L G A +T A + ++PIA++GM+CR Sbjct: 2026 LALSPTLIFDYPTPNALAGYIRTELAG------APQETTHAPVVRATDDDPIAIVGMSCR 2079 Query: 116 FSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEG 170 F G V LW +AE + ++E+P R A + D T G F+++V Sbjct: 2080 FPGGVDSPEALWQMVAEGRDVLSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVAD 2139 Query: 171 FDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRL 230 FD FF I P EA MDPQQR+ LE SW ALE AGI P L+ S TG+F GV + Y Sbjct: 2140 FDPAFFGIAPSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGVYTQGYGMG 2199 Query: 231 LFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGE 290 P + TG SSS+ + R+SY L + GP++ +DTACSSSLVA H+A +SL SGE Sbjct: 2200 AAPIAEGFRL---TGQSSSVASGRVSYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGE 2256 Query: 291 CDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDA 350 CDLA+ G V +P+++ F +S G C+A+ ADG EG G++V+ERLSDA Sbjct: 2257 CDLALAGGVTVNATPDIFVEFSRMRGLSVDGRCKAYAGAADGTGFSEGGGMLVVERLSDA 2316 Query: 351 RRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTG 410 RR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + AE+D VE HGTG Sbjct: 2317 RRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTG 2376 Query: 411 TSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLL 470 T++GD IEA AL +G+ R +PL +GSIK N+GH + AAG+AG+IK VL + R +LL Sbjct: 2377 TTLGDPIEAQALLATYGQDR--GQPLWLGSIKSNMGHTQAAAGVAGVIKMVLAM-RHELL 2433 Query: 471 PSGAF-EVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXX 529 P+ + P+P++ ++ ++++ E Q WP RPRRAGVSSFG GTNAH Sbjct: 2434 PATLHVDEPSPHVDWSAGAVSLLTEAQPWPGE--RPRRAGVSSFGISGTNAHVIIEAVPA 2491 Query: 530 XXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFE 589 VL WVVSA++AA + AQA RL E+VRA ELD DVG++L R+ FE Sbjct: 2492 VEPAHADAPALPVLPWVVSAKSAAALRAQAARLAEYVRAQGELDIADVGWTLAG-RATFE 2550 Query: 590 HRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCA 649 HRAVVVG RD LLAGL E+ P + GVA P GKTVFVFPGQG+Q LGMGR+L A Sbjct: 2551 HRAVVVGGDRDRLLAGLDELAADDPAASIIRGVATPAGKTVFVFPGQGSQTLGMGRQLHA 2610 Query: 650 GYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESW 709 GYP ELDRHL RPLR+V+WG D +LN+TEFAQPALFAVEVAL+RLLESW Sbjct: 2611 GYPVFAEAFDAVVAELDRHLLRPLRDVIWGDDENVLNSTEFAQPALFAVEVALFRLLESW 2670 Query: 710 GMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELR 769 G+RP VMGHS+GELSAAHV+G RGR MQALP GG M AVQA E ++R Sbjct: 2671 GVRPDFVMGHSIGELSAAHVAGVLSLQNAAVLVAARGRFMQALPEGGAMIAVQATEAQVR 2730 Query: 770 PLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLE 829 PLLG V +AAVNGP +VV+SG +A + +RL A+G RV RL+VSHAFHS LMEPM++ Sbjct: 2731 PLLGPDVGIAAVNGPAAVVISGDHDAAVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMID 2790 Query: 830 QFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGAT 889 +F VA + +P IP+ISN+TGQ A+D+GS +YW H+R+AVRFADSV FA SAGAT Sbjct: 2791 EFGTVAAGLAIDKPVIPIISNLTGQPAADDFGSPEYWKCHVRDAVRFADSVRFAQSAGAT 2850 Query: 890 RFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVL 949 RF+EVGP+ GLT+ IEE+LA VV V LRKDRPEP DW L Sbjct: 2851 RFLEVGPSSGLTAAIEETLADAPVVTVSALRKDRPEPVALVNAVAQGWVCGMDVDWRGAL 2910 Query: 950 AGCGGQRVGLPTYAFAHERFWLA 972 G V LPTYAF RFWL+ Sbjct: 2911 G--TGHLVDLPTYAFDRRRFWLS 2931 Score = 590 bits (1521), Expect = e-166 Identities = 371/885 (41%), Positives = 497/885 (56%), Gaps = 27/885 (3%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +AE + I+E+P R AA D D + Sbjct: 34 SSEPIAIVGMSCRFPGGVDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHKC 93 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F+++V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 94 YVNTGGFVDNVADFDPAFFGIAPSEALAMDPQHRMLLELSWEALERAGIDPSGLRGSATG 153 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R+SY L + GP++ +DTACSSSLV Sbjct: 154 VFAGLIVQGYGML----AEEIEGYRLTGMTSSVASGRVSYVLGLEGPAVSVDTACSSSLV 209 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A +SL SGECDLA+ G V +P V+ F ++P G C+A+ ADG+ E Sbjct: 210 ALHMAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRCKAYAGAADGVGWSE 269 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G ++V+ERLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 270 GGAMLVVERLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 329 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGL 457 AE+D VE HGTGT++GD IEA AL +G+ R +PL +GSIK N+GH + AAG+AG+ Sbjct: 330 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDR--GQPLWLGSIKSNMGHTQAAAGVAGV 387 Query: 458 IKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFG 516 IK VL + R +LLP+ + P+P++ ++ ++++ E Q WP RPRRAGVSSFG Sbjct: 388 IKMVLAM-RHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWPG--ERPRRAGVSSFGIS 444 Query: 517 GTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 576 GTNAH VL WVVSA++AA + AQA RL E+VRA ELD D Sbjct: 445 GTNAHVIIEAVPAVEPAHADAPALPVLPWVVSAKSAAALRAQAARLAEYVRAQGELDIAD 504 Query: 577 VGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQ 636 VG++L R+ FEHRAVVVG RD LLAGL E+ P + GVA P GKTVFVFPGQ Sbjct: 505 VGWTL-AGRATFEHRAVVVGGDRDRLLAGLDELAADDPAASIIRGVATPAGKTVFVFPGQ 563 Query: 637 GAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPAL 695 G+QWLGM EL P + L + + GA A ++ + QPAL Sbjct: 564 GSQWLGMATELLDTAPVFAQHIQACEEAFAEFVDWSLIDALRGAPGAAGMDRVDVVQPAL 623 Query: 696 FAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGG 755 FAV V+L L +S G+ P V+GHS GE++AA+V+G +R +L+++L G Sbjct: 624 FAVMVSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLRSLAGP 683 Query: 756 GVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRR 812 G M ++ + R LL G +VS+AAVNG +VV+SG A+ + A R RR Sbjct: 684 GGMLSIACSTERARELLAPYGNRVSIAAVNGRSAVVVSGEGAALDELAAFCADLALRTRR 743 Query: 813 LAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIRE 872 + V +A HSV +E + E + I S VTG + ADYW R+IR+ Sbjct: 744 IDVDYASHSVEVEAIREDLAQALTGIEPRSSRIAFFSTVTGNRLDTAGLDADYWYRNIRQ 803 Query: 873 AVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL-----AQVSVVAVPTLRKDRPEPF 927 V+F +V A G F+E P L + IE+++ + +PTL +D Sbjct: 804 TVQFDQTVRSAAEHGYRTFIESSPHPALVAGIEDTVNDSLPGDTEAIVIPTLGRDDGGLE 863 Query: 928 XXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 W VL G G V LPTYAF RFWL+ Sbjct: 864 RFLTSAATAFVAGVNVAWRGVLDGAG--FVELPTYAFDRRRFWLS 906 Score = 88.2 bits (217), Expect = 1e-14 Identities = 45/87 (51%), Positives = 57/87 (65%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG A +D +AF + G SL+AVE+RNRLKT Sbjct: 1964 RLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTA 2023 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ LS T FDYPTP LA ++ + L Sbjct: 2024 TGLALSPTLIFDYPTPNALAGYIRTEL 2050 Score = 77.4 bits (189), Expect = 2e-11 Identities = 43/112 (38%), Positives = 59/112 (52%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQQA +L +V + A VLG + +AF + G SL+AVE+RNRLK Sbjct: 4003 RLEGLPEDEQQAVLLDLVRSNIATVLGSSSPEAIHPDRAFQELGFDSLTAVEMRNRLKAA 4062 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIV 1121 TG+ LS T FDYP LA ++ L + AAA I + + Sbjct: 4063 TGLALSPTLIFDYPNSAALAGYMYRELVGTSEQPTAAAAPGEAEIQRVVGSI 4114 Score = 75.5 bits (184), Expect = 9e-11 Identities = 42/97 (43%), Positives = 56/97 (57%), Gaps = 2/97 (2%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQQA +L +V + A VLG + +AF + G SL+AVE+RNRLK Sbjct: 4003 RLEGLPEDEQQAVLLDLVRSNIATVLGSSSPEAIHPDRAFQELGFDSLTAVEMRNRLKAA 4062 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL--HHQNPTGA 2116 TG+ LS T FDYP LA ++ L + PT A Sbjct: 4063 TGLALSPTLIFDYPNSAALAGYMYRELVGTSEQPTAA 4099 >tr|Q73Z07|Q73Z07_MYCPA Tax_Id=1770 (pks12)SubName: Full=Pks12;[Mycobacterium paratuberculosis] Length = 4170 Score = 1168 bits (3021), Expect = 0.0 Identities = 605/976 (61%), Positives = 713/976 (73%), Gaps = 9/976 (0%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG A +D +AF + G SL+AVE+RNRLKT Sbjct: 1963 RLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTA 2022 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TG+ LS T FDYPTP LA ++ + L + A V R D+PIAIVGM CR+PG Sbjct: 2023 TGLALSPTLIFDYPTPNALAGYIRTELAGAPQEITHAPV-VRATDDDPIAIVGMSCRFPG 2081 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV SP LWQ+VA G DV+ EFP DRGWD+ +++PDPD G YTR GGFV +VADFDP Sbjct: 2082 GVDSPEALWQMVAEGRDVLSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFDP 2141 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ 1249 FFGI+P EALAMDPQQR+ LE SWEALE AGIDP LRGS+TG+F G+Y GYG+G + Sbjct: 2142 AFFGIAPSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGVYTQGYGMGAAP 2201 Query: 1250 -AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALA 1308 A+ + TG +SVASGR+SY LGL GPA+SVDTACSSSLVALH+A SLR+GECDLALA Sbjct: 2202 IAEGFRLTGQSSSVASGRVSYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALA 2261 Query: 1309 GGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQP 1368 GG+TV ATP++F+ FSR RGLA DGRCKA+A AADGTGFSEG MLV++RLSDARR G Sbjct: 2262 GGATVNATPTVFVEFSRHRGLAPDGRCKAYAGAADGTGFSEGGAMLVVERLSDARRLGHS 2321 Query: 1369 VLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDP 1428 VLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT LGDP Sbjct: 2322 VLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDP 2381 Query: 1429 IEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHID 1488 IEAQALLATYG+D PLWLGSIKSNMGH+QAAAGVAGVIKMV AMRH+LLPATLH+D Sbjct: 2382 IEAQALLATYGQDR--GQPLWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVD 2439 Query: 1489 QPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXX 1548 +PS HVDWS G V LLTEA+ WP RPRRAGVSSFG+SGTNAH Sbjct: 2440 EPSPHVDWSAGAVSLLTEAQPWPGE--RPRRAGVSSFGISGTNAHVIIEAVPAAEPAHAD 2497 Query: 1549 XXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVG 1608 VL W+VSA++AA + AQA RL E+VRA ELD DVG++L R+ FEHRAVVVG Sbjct: 2498 APALPVLPWMVSAKSAAALRAQAARLAEYVRAHGELDIADVGWTLAG-RATFEHRAVVVG 2556 Query: 1609 AGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXX 1668 RD LLAGL E+ P + GVA P GKTVFVFPGQG+Q LGMGR+L AGYP Sbjct: 2557 GDRDRLLAGLDELSTDDPAASIIRGVATPAGKTVFVFPGQGSQTLGMGRQLHAGYPVFAE 2616 Query: 1669 XXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLV 1728 ELDRHL RPLR+V+WG D +LN+TEFAQPALFAVEVAL+RLLESWG+RP V Sbjct: 2617 AFDAVVAELDRHLLRPLRDVIWGDDENVLNSTEFAQPALFAVEVALFRLLESWGVRPDFV 2676 Query: 1729 MGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQV 1788 MGHS+GELSAAHV+G RGR MQALP GG M AVQA E ++RPLLG V Sbjct: 2677 MGHSIGELSAAHVAGVLSLQNAAVLVAARGRFMQALPEGGAMIAVQATEAQVRPLLGPDV 2736 Query: 1789 SVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVAD 1848 +AAVNGP +VV+SG +A + +RL A+G RV RL+VSHAFHS LMEPM+++F VA Sbjct: 2737 GIAAVNGPAAVVISGDHDAAVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTVAA 2796 Query: 1849 EVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGP 1908 + + +P IP+ISN+TGQ A+D+GS +YW RH+R+AVRFADSV FA SAGATRF+EVGP Sbjct: 2797 GLASDKPVIPIISNLTGQPAADDFGSPEYWKRHVRDAVRFADSVRFAQSAGATRFLEVGP 2856 Query: 1909 AGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQR 1968 + GLT+ IEE+LA VV V LRKDRPEP DW L G Sbjct: 2857 SSGLTAAIEETLADAPVVTVSALRKDRPEPVALVNAVAQGWVCGMDVDWRGALG--TGHL 2914 Query: 1969 VGLPTYAFAHERFWLA 1984 V LPTYAF RFWL+ Sbjct: 2915 VDLPTYAFDRRRFWLS 2930 Score = 859 bits (2220), Expect = 0.0 Identities = 475/881 (53%), Positives = 574/881 (65%), Gaps = 16/881 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA G DVI EFP DRGWD+ L+DPDPDA K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 Y GGFV +VADFDP FFGI+P EALAMDPQQR+ LE SWEALE AGIDP LRGS+T Sbjct: 92 CYVNTGGFVDNVADFDPAFFGIAPSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR+SY LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVQGYGMLAEEIEGYRLTGMTSSVASGRVSYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG+TV ATP++F+ FSR RGLA DGRCKA+A AADG G+SEG Sbjct: 212 MAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRCKAYAGAADGVGWSEGGA 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLV++RLSDARR G VLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVVERLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKM 1472 VDVVE HGTGT LGDPIEAQALLATYG+D PLWLGSIKSNMGH+QAAAGVAGVIKM Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDR--GQPLWLGSIKSNMGHTQAAAGVAGVIKM 389 Query: 1473 VEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNA 1532 V AMRH+LLPATLH+D+PS HVDWS G V LLTEA+ WP RPRRAGVSSFG+SGTNA Sbjct: 390 VLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWPG--ERPRRAGVSSFGISGTNA 447 Query: 1533 HXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYS 1592 H VL W+VSA++AA + AQA RL E+VRA ELD DVG++ Sbjct: 448 HVIIEAVPAAEPAHADAPALPVLPWMVSAKSAAALRAQAARLAEYVRAHGELDIADVGWT 507 Query: 1593 LVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQW 1652 L R+ FEHRAVVVG RD LLAGL E+ P + GVA P GKTVFVFPGQG+QW Sbjct: 508 L-AGRATFEHRAVVVGGDRDRLLAGLDELSTDDPAASIIRGVATPAGKTVFVFPGQGSQW 566 Query: 1653 LGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAVE 1711 LGM EL P + L + + GA A ++ + QPALFAV Sbjct: 567 LGMATELLDTAPVFAQHIQACEEAFAEFVDWSLIDALRGAPGAAGMDRVDVVQPALFAVM 626 Query: 1712 VALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMY 1771 V+L L +S G+ P V+GHS GE++AA+V+G +R +L+++L G G M Sbjct: 627 VSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLRSLAGPGGML 686 Query: 1772 AVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVS 1828 ++ + R LL G +VS+AAVNG SVV+SG A+ + A R RR+ V Sbjct: 687 SIACSTERARELLAPYGNRVSIAAVNGRSSVVVSGEGAALDELAAFCADLALRTRRIDVD 746 Query: 1829 HAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRF 1888 +A HSV +E + E + I S VTG + ADYW R+IR+ V+F Sbjct: 747 YASHSVEVEAIREDLAQALTGIEPRSSRIAFFSTVTGNRLDTAGLDADYWYRNIRQTVQF 806 Query: 1889 ADSVCFAHSAGATRFVEVGPAGGLTSLIEESL-----AQVSVVAVPTLRKDRPEPFXXXX 1943 +V A G F+E P L + IE+++ + +PTL +D Sbjct: 807 DQAVRSAAEHGYRTFIESSPHPALVAGIEDTVNDSLPGDTEAIVIPTLGRDDGGLERFLT 866 Query: 1944 XXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 W VL G G V LPTYAF RFWL+ Sbjct: 867 SAATAFVAGVNVAWRGVLDGAG--FVELPTYAFDRRRFWLS 905 Score = 829 bits (2141), Expect = 0.0 Identities = 474/983 (48%), Positives = 612/983 (62%), Gaps = 30/983 (3%) Query: 3 DGLHSAD---ALQEWFTHYIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLG 58 DGL A+ L E +IA G +AE ++ D ++LG S+ + + L G Sbjct: 1965 DGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTATG 2024 Query: 59 ICVPDLAVWDNPSAHDV---IKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACR 115 + + ++D P+ + + I++ L G A + A + ++PIA++GM+CR Sbjct: 2025 LALSPTLIFDYPTPNALAGYIRTELAG------APQEITHAPVVRATDDDPIAIVGMSCR 2078 Query: 116 FSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEG 170 F G V LW +AE + ++E+P R A + D T G F+++V Sbjct: 2079 FPGGVDSPEALWQMVAEGRDVLSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVAD 2138 Query: 171 FDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRL 230 FD FF I P EA MDPQQR+ LE SW ALE AGI P L+ S TG+F GV + Y Sbjct: 2139 FDPAFFGIAPSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGVYTQGYGMG 2198 Query: 231 LFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGE 290 P + TG SSS+ + R+SY L + GP++ +DTACSSSLVA H+A +SL SGE Sbjct: 2199 AAPIAEGFRL---TGQSSSVASGRVSYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGE 2255 Query: 291 CDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDA 350 CDLA+ G V +P V+ F ++P G C+A+ ADG EG ++V+ERLSDA Sbjct: 2256 CDLALAGGATVNATPTVFVEFSRHRGLAPDGRCKAYAGAADGTGFSEGGAMLVVERLSDA 2315 Query: 351 RRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTG 410 RR G +VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + AE+D VE HGTG Sbjct: 2316 RRLGHSVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTG 2375 Query: 411 TSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLL 470 T++GD IEA AL +G+ R +PL +GSIK N+GH + AAG+AG+IK VL + R +LL Sbjct: 2376 TTLGDPIEAQALLATYGQDR--GQPLWLGSIKSNMGHTQAAAGVAGVIKMVLAM-RHELL 2432 Query: 471 PSGAF-EVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXX 529 P+ + P+P++ ++ ++++ E Q WP RPRRAGVSSFG GTNAH Sbjct: 2433 PATLHVDEPSPHVDWSAGAVSLLTEAQPWPGE--RPRRAGVSSFGISGTNAHVIIEAVPA 2490 Query: 530 XXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFE 589 VL W+VSA++AA + AQA RL E+VRA ELD DVG++L R+ FE Sbjct: 2491 AEPAHADAPALPVLPWMVSAKSAAALRAQAARLAEYVRAHGELDIADVGWTLAG-RATFE 2549 Query: 590 HRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCA 649 HRAVVVG RD LLAGL E+ P + GVA P GKTVFVFPGQG+Q LGMGR+L A Sbjct: 2550 HRAVVVGGDRDRLLAGLDELSTDDPAASIIRGVATPAGKTVFVFPGQGSQTLGMGRQLHA 2609 Query: 650 GYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESW 709 GYP ELDRHL RPLR+V+WG D +LN+TEFAQPALFAVEVAL+RLLESW Sbjct: 2610 GYPVFAEAFDAVVAELDRHLLRPLRDVIWGDDENVLNSTEFAQPALFAVEVALFRLLESW 2669 Query: 710 GMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELR 769 G+RP VMGHS+GELSAAHV+G RGR MQALP GG M AVQA E ++R Sbjct: 2670 GVRPDFVMGHSIGELSAAHVAGVLSLQNAAVLVAARGRFMQALPEGGAMIAVQATEAQVR 2729 Query: 770 PLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLE 829 PLLG V +AAVNGP +VV+SG +A + +RL A+G RV RL+VSHAFHS LMEPM++ Sbjct: 2730 PLLGPDVGIAAVNGPAAVVISGDHDAAVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMID 2789 Query: 830 QFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGAT 889 +F VA + + +P IP+ISN+TGQ A+D+GS +YW RH+R+AVRFADSV FA SAGAT Sbjct: 2790 EFGTVAAGLASDKPVIPIISNLTGQPAADDFGSPEYWKRHVRDAVRFADSVRFAQSAGAT 2849 Query: 890 RFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVL 949 RF+EVGP+ GLT+ IEE+LA VV V LRKDRPEP DW L Sbjct: 2850 RFLEVGPSSGLTAAIEETLADAPVVTVSALRKDRPEPVALVNAVAQGWVCGMDVDWRGAL 2909 Query: 950 AGCGGQRVGLPTYAFAHERFWLA 972 G V LPTYAF RFWL+ Sbjct: 2910 G--TGHLVDLPTYAFDRRRFWLS 2930 Score = 590 bits (1521), Expect = e-166 Identities = 371/885 (41%), Positives = 498/885 (56%), Gaps = 27/885 (3%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +AE + I+E+P R AA D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHKC 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F+++V FD FF I P EA MDPQQR+ LE SW ALE AGI P L+ S TG Sbjct: 93 YVNTGGFVDNVADFDPAFFGIAPSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R+SY L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVQGYGML----AEEIEGYRLTGMTSSVASGRVSYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A +SL SGECDLA+ G V +P V+ F ++P G C+A+ ADG+ E Sbjct: 209 ALHMAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRCKAYAGAADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G ++V+ERLSDARR G +VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGAMLVVERLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGL 457 AE+D VE HGTGT++GD IEA AL +G+ R +PL +GSIK N+GH + AAG+AG+ Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDR--GQPLWLGSIKSNMGHTQAAAGVAGV 386 Query: 458 IKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFG 516 IK VL + R +LLP+ + P+P++ ++ ++++ E Q WP RPRRAGVSSFG Sbjct: 387 IKMVLAM-RHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWPG--ERPRRAGVSSFGIS 443 Query: 517 GTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 576 GTNAH VL W+VSA++AA + AQA RL E+VRA ELD D Sbjct: 444 GTNAHVIIEAVPAAEPAHADAPALPVLPWMVSAKSAAALRAQAARLAEYVRAHGELDIAD 503 Query: 577 VGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQ 636 VG++L R+ FEHRAVVVG RD LLAGL E+ P + GVA P GKTVFVFPGQ Sbjct: 504 VGWTL-AGRATFEHRAVVVGGDRDRLLAGLDELSTDDPAASIIRGVATPAGKTVFVFPGQ 562 Query: 637 GAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPAL 695 G+QWLGM EL P + L + + GA A ++ + QPAL Sbjct: 563 GSQWLGMATELLDTAPVFAQHIQACEEAFAEFVDWSLIDALRGAPGAAGMDRVDVVQPAL 622 Query: 696 FAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGG 755 FAV V+L L +S G+ P V+GHS GE++AA+V+G +R +L+++L G Sbjct: 623 FAVMVSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLRSLAGP 682 Query: 756 GVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRR 812 G M ++ + R LL G +VS+AAVNG SVV+SG A+ + A R RR Sbjct: 683 GGMLSIACSTERARELLAPYGNRVSIAAVNGRSSVVVSGEGAALDELAAFCADLALRTRR 742 Query: 813 LAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIRE 872 + V +A HSV +E + E + I S VTG + ADYW R+IR+ Sbjct: 743 IDVDYASHSVEVEAIREDLAQALTGIEPRSSRIAFFSTVTGNRLDTAGLDADYWYRNIRQ 802 Query: 873 AVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESL-----AQVSVVAVPTLRKDRPEPF 927 V+F +V A G F+E P L + IE+++ + +PTL +D Sbjct: 803 TVQFDQAVRSAAEHGYRTFIESSPHPALVAGIEDTVNDSLPGDTEAIVIPTLGRDDGGLE 862 Query: 928 XXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 W VL G G V LPTYAF RFWL+ Sbjct: 863 RFLTSAATAFVAGVNVAWRGVLDGAG--FVELPTYAFDRRRFWLS 905 Score = 88.2 bits (217), Expect = 1e-14 Identities = 45/87 (51%), Positives = 57/87 (65%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG A +D +AF + G SL+AVE+RNRLKT Sbjct: 1963 RLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTA 2022 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ LS T FDYPTP LA ++ + L Sbjct: 2023 TGLALSPTLIFDYPTPNALAGYIRTEL 2049 Score = 77.4 bits (189), Expect = 2e-11 Identities = 43/112 (38%), Positives = 59/112 (52%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQQA +L +V + A VLG + +AF + G SL+AVE+RNRLK Sbjct: 4002 RLEGLPEDEQQAVLLDLVRSNIATVLGSSSPEAIHPDRAFQELGFDSLTAVEMRNRLKAA 4061 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIV 1121 TG+ LS T FDYP LA ++ L + AAA I + + Sbjct: 4062 TGLALSPTLIFDYPNSAALAGYMYRELVGTSEQPTAAAAPGEAEIQRVVGSI 4113 Score = 75.5 bits (184), Expect = 9e-11 Identities = 42/97 (43%), Positives = 56/97 (57%), Gaps = 2/97 (2%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQQA +L +V + A VLG + +AF + G SL+AVE+RNRLK Sbjct: 4002 RLEGLPEDEQQAVLLDLVRSNIATVLGSSSPEAIHPDRAFQELGFDSLTAVEMRNRLKAA 4061 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL--HHQNPTGA 2116 TG+ LS T FDYP LA ++ L + PT A Sbjct: 4062 TGLALSPTLIFDYPNSAALAGYMYRELVGTSEQPTAA 4098 >tr|Q7VES2|Q7VES2_MYCBO Tax_Id=1765 (pks12)SubName: Full=Probable polyketide synthase pks12;[Mycobacterium bovis] Length = 4151 Score = 1159 bits (2998), Expect = 0.0 Identities = 607/980 (61%), Positives = 713/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2067 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2068 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2127 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQQR+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2128 FDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2187 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2188 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2247 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLVLQRLSDARR Sbjct: 2248 ALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRL 2307 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2308 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2367 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2368 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2427 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2428 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2486 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2487 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2544 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2545 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2604 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2605 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2664 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2665 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2724 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2725 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2784 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2785 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2844 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2845 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2902 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2903 EAQFVELPTYAFQRRRFWLS 2922 Score = 843 bits (2177), Expect = 0.0 Identities = 469/882 (53%), Positives = 567/882 (64%), Gaps = 15/882 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y R GGFV VADFDP FFGISP EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 SYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG G Sbjct: 212 MAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIK Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK 391 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTN Sbjct: 392 MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGTN 450 Query: 1532 AHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 1591 AH GP V+ WVVSA++ + + QA RL +VR LD DVG+ Sbjct: 451 AHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGW 509 Query: 1592 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 1651 SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+Q Sbjct: 510 SL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQ 568 Query: 1652 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAV 1710 WLGMG EL P + L +V+ GA A L+ + QP LFAV Sbjct: 569 WLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAV 628 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G M Sbjct: 629 MVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGM 688 Query: 1771 YAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ V Sbjct: 689 VSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEV 748 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVR 1887 +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 DYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVL 808 Query: 1888 FADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXXX 1942 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 FDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFL 868 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 817 bits (2110), Expect = 0.0 Identities = 465/953 (48%), Positives = 597/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1985 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2040 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2041 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2098 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQQR+LLE SW AL Sbjct: 2099 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEAL 2158 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2159 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2215 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P+++ F +SP G Sbjct: 2216 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDG 2275 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+AF A ADG EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2276 RCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2335 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2336 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2395 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2396 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2454 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2455 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2512 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2513 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2571 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2572 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2631 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2632 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2691 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2692 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2751 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2752 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2811 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2812 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2871 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2872 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2922 Score = 565 bits (1457), Expect = e-158 Identities = 360/886 (40%), Positives = 491/886 (55%), Gaps = 26/886 (2%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +A+ + ++E+P R A D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKS 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F++ V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 93 YARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R++Y L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVGGYGML----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ E Sbjct: 209 ALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAG 456 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+AG Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG 388 Query: 457 LIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 +IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 VIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGI 446 Query: 516 GGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 SGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVA 505 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPG Sbjct: 506 DVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPG 564 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPA 694 QG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 QGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPV 624 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G Sbjct: 625 LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAG 684 Query: 755 GGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R R Sbjct: 685 PGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTR 744 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 R+ V +A HSV +E + + S VTG + ADYW R++R Sbjct: 745 RIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVR 804 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEP 926 + V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 QTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGL 864 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 HRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTEL 2038 Score = 80.1 bits (196), Expect = 4e-12 Identities = 49/114 (42%), Positives = 63/114 (55%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL + EQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 3984 RLHGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQDLGFDSLTAVEMRNRLKSA 4043 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG++LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4044 TGLSLSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4097 Score = 79.7 bits (195), Expect = 5e-12 Identities = 42/92 (45%), Positives = 55/92 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL + EQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 3984 RLHGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQDLGFDSLTAVEMRNRLKSA 4043 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG++LS T FDYP LA ++ L +P Sbjct: 4044 TGLSLSPTLIFDYPNSAALAGYMRRELLGSSP 4075 >tr|C6DQ18|C6DQ18_MYCTK Tax_Id=478434 SubName: Full=Putative uncharacterized protein;[Mycobacterium tuberculosis] Length = 4152 Score = 1159 bits (2998), Expect = 0.0 Identities = 607/980 (61%), Positives = 713/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1953 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2012 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2013 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2068 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2069 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2128 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQQR+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2129 FDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2188 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2189 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2248 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLVLQRLSDARR Sbjct: 2249 ALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRL 2308 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2309 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2368 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2369 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2428 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2429 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2487 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2488 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2545 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2546 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2605 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2606 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2665 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2666 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2725 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2726 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2785 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2786 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2845 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2846 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2903 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2904 EAQFVELPTYAFQRRRFWLS 2923 Score = 841 bits (2173), Expect = 0.0 Identities = 467/883 (52%), Positives = 568/883 (64%), Gaps = 16/883 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPDA G Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDAAGA 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 YTR GGFV V DFDP FFG+ P EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 CYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 GVF G+ GYG+ ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVAL Sbjct: 152 GVFAGVMTQGYGMFAAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVAL 211 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 H+A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG Sbjct: 212 HMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGG 271 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 GMLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A Sbjct: 272 GMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAA 331 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVI 1470 +VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVI Sbjct: 332 EVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVI 391 Query: 1471 KMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGT 1530 KMV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGT Sbjct: 392 KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGT 450 Query: 1531 NAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVG 1590 NAH GP V+ WVVSA++ + + QA RL +VR LD DVG Sbjct: 451 NAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVG 509 Query: 1591 YSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGA 1650 +SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+ Sbjct: 510 WSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGS 568 Query: 1651 QWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFA 1709 QWLGMG EL P + L +V+ GA A L+ + QP LFA Sbjct: 569 QWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFA 628 Query: 1710 VEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGV 1769 V V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G Sbjct: 629 VMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGG 688 Query: 1770 MYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLA 1826 M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ Sbjct: 689 MVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIE 748 Query: 1827 VSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAV 1886 V +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 VDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTV 808 Query: 1887 RFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXX 1941 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 LFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRF 868 Query: 1942 XXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 909 Score = 817 bits (2110), Expect = 0.0 Identities = 465/953 (48%), Positives = 597/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1986 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2041 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2042 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2099 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQQR+LLE SW AL Sbjct: 2100 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEAL 2159 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2160 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2216 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P+++ F +SP G Sbjct: 2217 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDG 2276 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+AF A ADG EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2277 RCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2336 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2337 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2396 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2397 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2455 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2456 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2513 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2514 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2572 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2573 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2632 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2633 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2692 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2693 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2752 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2753 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2812 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2813 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2872 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2873 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2923 Score = 565 bits (1457), Expect = e-158 Identities = 357/887 (40%), Positives = 488/887 (55%), Gaps = 27/887 (3%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYG 162 ++EPIA++GM+CRF G V LW +A+ + ++E+P R G A + + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDR-GWDLAGLFDPDPDAAGA 91 Query: 163 C------FLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHT 216 C F++ V FD FF + P EA MDPQ R+LLE SW ALE AGI P L+ S T Sbjct: 92 CYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 217 GVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSL 276 GVF GV + Y + TG SS+ + R++Y L + GP++ +DTACSSSL Sbjct: 152 GVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSL 208 Query: 277 VAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRG 336 VA H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ Sbjct: 209 VALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWS 268 Query: 337 EGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADI 396 EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 EGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGL 328 Query: 397 DPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIA 455 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+A Sbjct: 329 SAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVA 388 Query: 456 GLIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFG 514 G+IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 GVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFG 446 Query: 515 FGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 574 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 ISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDV 505 Query: 575 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFP 634 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFP Sbjct: 506 ADVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFP 564 Query: 635 GQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQP 693 GQG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 GQGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQP 624 Query: 694 ALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALP 753 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L Sbjct: 625 VLFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLA 684 Query: 754 GGGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRV 810 G G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R Sbjct: 685 GPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRT 744 Query: 811 RRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHI 870 RR+ V +A HSV +E + + S VTG + ADYW R++ Sbjct: 745 RRIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNV 804 Query: 871 REAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPE 925 R+ V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 RQTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGG 864 Query: 926 PFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 LHRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 909 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1953 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2012 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2013 TGLSLSPTLIFDYPTPNRLASYIRTEL 2039 Score = 79.0 bits (193), Expect = 8e-12 Identities = 48/114 (42%), Positives = 63/114 (55%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3985 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4044 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG+ LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4045 TGLALSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4098 Score = 78.6 bits (192), Expect = 1e-11 Identities = 41/92 (44%), Positives = 55/92 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3985 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4044 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG+ LS T FDYP LA ++ L +P Sbjct: 4045 TGLALSPTLIFDYPNSAALAGYMRRELLGSSP 4076 >tr|C1APW8|C1APW8_MYCBT Tax_Id=561275 (pks12)SubName: Full=Putative polyketide synthase;[Mycobacterium bovis] Length = 4151 Score = 1159 bits (2998), Expect = 0.0 Identities = 607/980 (61%), Positives = 713/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2067 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2068 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2127 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQQR+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2128 FDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2187 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2188 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2247 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLVLQRLSDARR Sbjct: 2248 ALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRL 2307 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2308 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2367 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2368 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2427 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2428 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2486 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2487 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2544 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2545 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2604 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2605 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2664 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2665 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2724 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2725 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2784 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2785 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2844 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2845 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2902 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2903 EAQFVELPTYAFQRRRFWLS 2922 Score = 843 bits (2177), Expect = 0.0 Identities = 469/882 (53%), Positives = 567/882 (64%), Gaps = 15/882 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y R GGFV VADFDP FFGISP EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 SYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG G Sbjct: 212 MAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIK Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK 391 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTN Sbjct: 392 MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGTN 450 Query: 1532 AHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 1591 AH GP V+ WVVSA++ + + QA RL +VR LD DVG+ Sbjct: 451 AHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGW 509 Query: 1592 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 1651 SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+Q Sbjct: 510 SL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQ 568 Query: 1652 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAV 1710 WLGMG EL P + L +V+ GA A L+ + QP LFAV Sbjct: 569 WLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAV 628 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G M Sbjct: 629 MVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGM 688 Query: 1771 YAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ V Sbjct: 689 VSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEV 748 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVR 1887 +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 DYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVL 808 Query: 1888 FADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXXX 1942 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 FDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFL 868 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 817 bits (2110), Expect = 0.0 Identities = 465/953 (48%), Positives = 597/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1985 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2040 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2041 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2098 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQQR+LLE SW AL Sbjct: 2099 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEAL 2158 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2159 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2215 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P+++ F +SP G Sbjct: 2216 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDG 2275 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+AF A ADG EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2276 RCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2335 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2336 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2395 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2396 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2454 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2455 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2512 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2513 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2571 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2572 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2631 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2632 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2691 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2692 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2751 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2752 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2811 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2812 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2871 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2872 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2922 Score = 565 bits (1457), Expect = e-158 Identities = 360/886 (40%), Positives = 491/886 (55%), Gaps = 26/886 (2%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +A+ + ++E+P R A D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKS 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F++ V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 93 YARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R++Y L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVGGYGML----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ E Sbjct: 209 ALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAG 456 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+AG Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG 388 Query: 457 LIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 +IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 VIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGI 446 Query: 516 GGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 SGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVA 505 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPG Sbjct: 506 DVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPG 564 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPA 694 QG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 QGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPV 624 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G Sbjct: 625 LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAG 684 Query: 755 GGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R R Sbjct: 685 PGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTR 744 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 R+ V +A HSV +E + + S VTG + ADYW R++R Sbjct: 745 RIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVR 804 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEP 926 + V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 QTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGL 864 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 HRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTEL 2038 Score = 79.3 bits (194), Expect = 6e-12 Identities = 48/114 (42%), Positives = 64/114 (56%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG++LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4044 TGLSLSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4097 Score = 79.0 bits (193), Expect = 8e-12 Identities = 41/92 (44%), Positives = 56/92 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG++LS T FDYP LA ++ L +P Sbjct: 4044 TGLSLSPTLIFDYPNSAALAGYMRRELLGSSP 4075 >tr|A1KK94|A1KK94_MYCBP Tax_Id=410289 (pks12)SubName: Full=Probable polyketide synthase pks12;[Mycobacterium bovis] Length = 4151 Score = 1159 bits (2998), Expect = 0.0 Identities = 607/980 (61%), Positives = 713/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2067 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2068 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2127 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQQR+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2128 FDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2187 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2188 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2247 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLVLQRLSDARR Sbjct: 2248 ALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRL 2307 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2308 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2367 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2368 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2427 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2428 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2486 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2487 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2544 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2545 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2604 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2605 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2664 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2665 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2724 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2725 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2784 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2785 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2844 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2845 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2902 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2903 EAQFVELPTYAFQRRRFWLS 2922 Score = 843 bits (2177), Expect = 0.0 Identities = 469/882 (53%), Positives = 567/882 (64%), Gaps = 15/882 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y R GGFV VADFDP FFGISP EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 SYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG G Sbjct: 212 MAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIK Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK 391 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTN Sbjct: 392 MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGTN 450 Query: 1532 AHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 1591 AH GP V+ WVVSA++ + + QA RL +VR LD DVG+ Sbjct: 451 AHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGW 509 Query: 1592 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 1651 SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+Q Sbjct: 510 SL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQ 568 Query: 1652 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAV 1710 WLGMG EL P + L +V+ GA A L+ + QP LFAV Sbjct: 569 WLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAV 628 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G M Sbjct: 629 MVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGM 688 Query: 1771 YAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ V Sbjct: 689 VSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEV 748 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVR 1887 +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 DYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVL 808 Query: 1888 FADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXXX 1942 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 FDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFL 868 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 817 bits (2110), Expect = 0.0 Identities = 465/953 (48%), Positives = 597/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1985 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2040 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2041 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2098 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQQR+LLE SW AL Sbjct: 2099 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEAL 2158 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2159 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2215 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P+++ F +SP G Sbjct: 2216 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDG 2275 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+AF A ADG EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2276 RCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2335 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2336 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2395 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2396 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2454 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2455 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2512 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2513 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2571 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2572 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2631 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2632 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2691 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2692 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2751 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2752 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2811 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2812 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2871 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2872 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2922 Score = 565 bits (1457), Expect = e-158 Identities = 360/886 (40%), Positives = 491/886 (55%), Gaps = 26/886 (2%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +A+ + ++E+P R A D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKS 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F++ V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 93 YARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R++Y L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVGGYGML----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ E Sbjct: 209 ALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAG 456 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+AG Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG 388 Query: 457 LIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 +IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 VIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGI 446 Query: 516 GGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 SGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVA 505 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPG Sbjct: 506 DVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPG 564 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPA 694 QG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 QGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPV 624 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G Sbjct: 625 LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAG 684 Query: 755 GGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R R Sbjct: 685 PGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTR 744 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 R+ V +A HSV +E + + S VTG + ADYW R++R Sbjct: 745 RIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVR 804 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEP 926 + V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 QTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGL 864 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 HRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTEL 2038 Score = 79.3 bits (194), Expect = 6e-12 Identities = 48/114 (42%), Positives = 64/114 (56%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG++LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4044 TGLSLSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4097 Score = 79.0 bits (193), Expect = 8e-12 Identities = 41/92 (44%), Positives = 56/92 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG++LS T FDYP LA ++ L +P Sbjct: 4044 TGLSLSPTLIFDYPNSAALAGYMRRELLGSSP 4075 >tr|A5WP27|A5WP27_MYCTF Tax_Id=336982 SubName: Full=Putative uncharacterized protein;[Mycobacterium tuberculosis] Length = 4151 Score = 1159 bits (2998), Expect = 0.0 Identities = 607/980 (61%), Positives = 713/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2067 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2068 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2127 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQQR+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2128 FDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2187 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2188 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2247 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLVLQRLSDARR Sbjct: 2248 ALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRL 2307 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2308 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2367 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2368 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2427 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2428 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2486 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2487 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2544 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2545 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2604 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2605 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2664 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2665 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2724 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2725 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2784 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2785 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2844 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2845 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2902 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2903 EAQFVELPTYAFQRRRFWLS 2922 Score = 843 bits (2177), Expect = 0.0 Identities = 469/882 (53%), Positives = 567/882 (64%), Gaps = 15/882 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y R GGFV VADFDP FFGISP EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 SYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG G Sbjct: 212 MAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIK Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK 391 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTN Sbjct: 392 MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGTN 450 Query: 1532 AHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 1591 AH GP V+ WVVSA++ + + QA RL +VR LD DVG+ Sbjct: 451 AHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGW 509 Query: 1592 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 1651 SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+Q Sbjct: 510 SL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQ 568 Query: 1652 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAV 1710 WLGMG EL P + L +V+ GA A L+ + QP LFAV Sbjct: 569 WLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAV 628 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G M Sbjct: 629 MVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGM 688 Query: 1771 YAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ V Sbjct: 689 VSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEV 748 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVR 1887 +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 DYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVL 808 Query: 1888 FADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXXX 1942 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 FDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFL 868 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 817 bits (2110), Expect = 0.0 Identities = 465/953 (48%), Positives = 597/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1985 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2040 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2041 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2098 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQQR+LLE SW AL Sbjct: 2099 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEAL 2158 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2159 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2215 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P+++ F +SP G Sbjct: 2216 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDG 2275 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+AF A ADG EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2276 RCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2335 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2336 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2395 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2396 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2454 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2455 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2512 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2513 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2571 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2572 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2631 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2632 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2691 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2692 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2751 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2752 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2811 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2812 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2871 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2872 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2922 Score = 565 bits (1457), Expect = e-158 Identities = 360/886 (40%), Positives = 491/886 (55%), Gaps = 26/886 (2%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +A+ + ++E+P R A D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKS 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F++ V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 93 YARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R++Y L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVGGYGML----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ E Sbjct: 209 ALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAG 456 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+AG Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG 388 Query: 457 LIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 +IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 VIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGI 446 Query: 516 GGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 SGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVA 505 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPG Sbjct: 506 DVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPG 564 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPA 694 QG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 QGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPV 624 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G Sbjct: 625 LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAG 684 Query: 755 GGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R R Sbjct: 685 PGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTR 744 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 R+ V +A HSV +E + + S VTG + ADYW R++R Sbjct: 745 RIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVR 804 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEP 926 + V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 QTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGL 864 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 HRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTEL 2038 Score = 79.0 bits (193), Expect = 8e-12 Identities = 48/114 (42%), Positives = 63/114 (55%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG+ LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4097 Score = 78.6 bits (192), Expect = 1e-11 Identities = 41/92 (44%), Positives = 55/92 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG+ LS T FDYP LA ++ L +P Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSP 4075 >tr|A2VJF6|A2VJF6_MYCTU Tax_Id=348776 SubName: Full=Putative uncharacterized protein;[Mycobacterium tuberculosis C] Length = 4151 Score = 1159 bits (2998), Expect = 0.0 Identities = 607/980 (61%), Positives = 713/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2067 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2068 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2127 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQQR+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2128 FDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2187 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2188 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2247 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLVLQRLSDARR Sbjct: 2248 ALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRL 2307 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2308 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2367 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2368 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2427 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2428 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2486 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2487 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2544 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2545 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2604 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2605 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2664 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2665 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2724 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2725 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2784 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2785 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2844 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2845 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2902 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2903 EAQFVELPTYAFQRRRFWLS 2922 Score = 843 bits (2177), Expect = 0.0 Identities = 469/882 (53%), Positives = 567/882 (64%), Gaps = 15/882 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y R GGFV VADFDP FFGISP EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 SYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG G Sbjct: 212 MAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIK Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK 391 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTN Sbjct: 392 MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGTN 450 Query: 1532 AHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 1591 AH GP V+ WVVSA++ + + QA RL +VR LD DVG+ Sbjct: 451 AHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGW 509 Query: 1592 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 1651 SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+Q Sbjct: 510 SL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQ 568 Query: 1652 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAV 1710 WLGMG EL P + L +V+ GA A L+ + QP LFAV Sbjct: 569 WLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAV 628 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G M Sbjct: 629 MVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGM 688 Query: 1771 YAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ V Sbjct: 689 VSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEV 748 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVR 1887 +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 DYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVL 808 Query: 1888 FADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXXX 1942 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 FDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFL 868 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 817 bits (2110), Expect = 0.0 Identities = 465/953 (48%), Positives = 597/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1985 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2040 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2041 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2098 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQQR+LLE SW AL Sbjct: 2099 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEAL 2158 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2159 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2215 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P+++ F +SP G Sbjct: 2216 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDG 2275 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+AF A ADG EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2276 RCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2335 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2336 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2395 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2396 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2454 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2455 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2512 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2513 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2571 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2572 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2631 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2632 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2691 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2692 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2751 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2752 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2811 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2812 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2871 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2872 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2922 Score = 565 bits (1457), Expect = e-158 Identities = 360/886 (40%), Positives = 491/886 (55%), Gaps = 26/886 (2%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +A+ + ++E+P R A D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKS 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F++ V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 93 YARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R++Y L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVGGYGML----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ E Sbjct: 209 ALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAG 456 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+AG Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG 388 Query: 457 LIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 +IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 VIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGI 446 Query: 516 GGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 SGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVA 505 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPG Sbjct: 506 DVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPG 564 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPA 694 QG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 QGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPV 624 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G Sbjct: 625 LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAG 684 Query: 755 GGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R R Sbjct: 685 PGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTR 744 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 R+ V +A HSV +E + + S VTG + ADYW R++R Sbjct: 745 RIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVR 804 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEP 926 + V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 QTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGL 864 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 HRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTEL 2038 Score = 79.0 bits (193), Expect = 8e-12 Identities = 48/114 (42%), Positives = 63/114 (55%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG+ LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4097 Score = 78.6 bits (192), Expect = 1e-11 Identities = 41/92 (44%), Positives = 55/92 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG+ LS T FDYP LA ++ L +P Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSP 4075 >tr|O53490|O53490_MYCTU Tax_Id=1773 (pks12)SubName: Full=Probable polyketide synthase pks12;[Mycobacterium tuberculosis] Length = 4151 Score = 1157 bits (2993), Expect = 0.0 Identities = 606/980 (61%), Positives = 712/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2067 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2068 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2127 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQ R+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2128 FDPAFFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2187 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2188 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2247 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLVLQRLSDARR Sbjct: 2248 ALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRL 2307 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2308 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2367 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2368 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2427 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2428 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2486 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2487 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2544 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2545 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2604 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2605 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2664 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2665 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2724 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2725 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2784 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2785 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2844 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2845 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2902 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2903 EAQFVELPTYAFQRRRFWLS 2922 Score = 843 bits (2177), Expect = 0.0 Identities = 469/882 (53%), Positives = 567/882 (64%), Gaps = 15/882 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y R GGFV VADFDP FFGISP EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 SYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG G Sbjct: 212 MAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIK Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK 391 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTN Sbjct: 392 MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGTN 450 Query: 1532 AHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 1591 AH GP V+ WVVSA++ + + QA RL +VR LD DVG+ Sbjct: 451 AHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGW 509 Query: 1592 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 1651 SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+Q Sbjct: 510 SL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQ 568 Query: 1652 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAV 1710 WLGMG EL P + L +V+ GA A L+ + QP LFAV Sbjct: 569 WLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAV 628 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G M Sbjct: 629 MVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGM 688 Query: 1771 YAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ V Sbjct: 689 VSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEV 748 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVR 1887 +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 DYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVL 808 Query: 1888 FADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXXX 1942 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 FDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFL 868 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 815 bits (2105), Expect = 0.0 Identities = 464/953 (48%), Positives = 596/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1985 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2040 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2041 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2098 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQ R+LLE SW AL Sbjct: 2099 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQHRMLLELSWEAL 2158 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2159 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2215 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P+++ F +SP G Sbjct: 2216 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDG 2275 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+AF A ADG EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2276 RCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2335 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2336 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2395 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2396 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2454 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2455 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2512 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2513 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2571 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2572 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2631 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2632 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2691 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2692 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2751 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2752 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2811 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2812 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2871 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2872 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2922 Score = 565 bits (1457), Expect = e-158 Identities = 360/886 (40%), Positives = 491/886 (55%), Gaps = 26/886 (2%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +A+ + ++E+P R A D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKS 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F++ V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 93 YARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R++Y L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVGGYGML----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ E Sbjct: 209 ALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAG 456 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+AG Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG 388 Query: 457 LIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 +IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 VIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGI 446 Query: 516 GGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 SGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVA 505 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPG Sbjct: 506 DVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPG 564 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPA 694 QG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 QGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPV 624 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G Sbjct: 625 LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAG 684 Query: 755 GGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R R Sbjct: 685 PGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTR 744 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 R+ V +A HSV +E + + S VTG + ADYW R++R Sbjct: 745 RIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVR 804 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEP 926 + V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 QTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGL 864 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 HRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTEL 2038 Score = 79.0 bits (193), Expect = 8e-12 Identities = 48/114 (42%), Positives = 63/114 (55%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG+ LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4097 Score = 78.6 bits (192), Expect = 1e-11 Identities = 41/92 (44%), Positives = 55/92 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG+ LS T FDYP LA ++ L +P Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSP 4075 >tr|A5U473|A5U473_MYCTA Tax_Id=419947 (pks12)SubName: Full=Polyketide synthase Pks12;[Mycobacterium tuberculosis] Length = 4151 Score = 1157 bits (2993), Expect = 0.0 Identities = 606/980 (61%), Positives = 712/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2067 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2068 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2127 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQ R+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2128 FDPAFFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2187 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2188 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2247 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLVLQRLSDARR Sbjct: 2248 ALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRL 2307 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2308 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2367 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2368 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2427 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2428 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2486 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2487 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2544 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2545 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2604 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2605 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2664 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2665 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2724 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2725 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2784 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2785 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2844 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2845 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2902 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2903 EAQFVELPTYAFQRRRFWLS 2922 Score = 843 bits (2177), Expect = 0.0 Identities = 469/882 (53%), Positives = 567/882 (64%), Gaps = 15/882 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y R GGFV VADFDP FFGISP EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 SYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG G Sbjct: 212 MAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIK Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK 391 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTN Sbjct: 392 MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGTN 450 Query: 1532 AHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 1591 AH GP V+ WVVSA++ + + QA RL +VR LD DVG+ Sbjct: 451 AHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGW 509 Query: 1592 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 1651 SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+Q Sbjct: 510 SL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQ 568 Query: 1652 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAV 1710 WLGMG EL P + L +V+ GA A L+ + QP LFAV Sbjct: 569 WLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAV 628 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G M Sbjct: 629 MVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGM 688 Query: 1771 YAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ V Sbjct: 689 VSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEV 748 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVR 1887 +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 DYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVL 808 Query: 1888 FADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXXX 1942 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 FDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFL 868 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 815 bits (2105), Expect = 0.0 Identities = 464/953 (48%), Positives = 596/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1985 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2040 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2041 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2098 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQ R+LLE SW AL Sbjct: 2099 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQHRMLLELSWEAL 2158 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2159 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2215 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P+++ F +SP G Sbjct: 2216 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDG 2275 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+AF A ADG EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2276 RCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2335 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2336 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2395 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2396 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2454 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2455 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2512 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2513 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2571 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2572 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2631 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2632 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2691 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2692 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2751 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2752 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2811 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2812 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2871 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2872 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2922 Score = 565 bits (1457), Expect = e-158 Identities = 360/886 (40%), Positives = 491/886 (55%), Gaps = 26/886 (2%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +A+ + ++E+P R A D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKS 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F++ V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 93 YARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R++Y L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVGGYGML----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ E Sbjct: 209 ALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAG 456 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+AG Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG 388 Query: 457 LIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 +IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 VIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGI 446 Query: 516 GGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 SGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVA 505 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPG Sbjct: 506 DVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPG 564 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPA 694 QG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 QGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPV 624 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G Sbjct: 625 LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAG 684 Query: 755 GGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R R Sbjct: 685 PGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTR 744 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 R+ V +A HSV +E + + S VTG + ADYW R++R Sbjct: 745 RIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVR 804 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEP 926 + V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 QTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGL 864 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 HRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTEL 2038 Score = 79.0 bits (193), Expect = 8e-12 Identities = 48/114 (42%), Positives = 63/114 (55%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG+ LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4097 Score = 78.6 bits (192), Expect = 1e-11 Identities = 41/92 (44%), Positives = 55/92 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG+ LS T FDYP LA ++ L +P Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSP 4075 >tr|Q7D7J7|Q7D7J7_MYCTU Tax_Id=1773 SubName: Full=Polyketide synthase;[Mycobacterium tuberculosis] Length = 4151 Score = 1152 bits (2981), Expect = 0.0 Identities = 602/980 (61%), Positives = 711/980 (72%), Gaps = 14/980 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 1070 TGVTLSATTAFDYPTPTQLADHL---LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP +LA ++ L+ L + + PA R ++PIAIVGM CR Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTELAGLPQEIKHTPAV----RTTSEDPIAIVGMACR 2067 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGGV+SP +W ++ G DV+ EFP DRGWD+ L++PDPDA G YTR GGFV V D Sbjct: 2068 YPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGD 2127 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQQR+LLE SWEALE AGIDP LRGS+TGVF G+ GYG+ Sbjct: 2128 FDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMF 2187 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2188 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDL 2247 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG GMLVLQRLSDARR Sbjct: 2248 ALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRL 2307 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2308 GHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2367 Query: 1426 GDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 GDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIKMV AMRH+LLPAT Sbjct: 2368 GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPAT 2427 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTNAH Sbjct: 2428 LHVDVPSPHVDWSAGAVELLTAPRVWPAGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPR 2486 Query: 1545 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 GP V+ WVVSA++ + + QA RL +VR LD DVG+SL RS+FEHRA Sbjct: 2487 REAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRA 2544 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+QWLGMG L AGYP Sbjct: 2545 VVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYP 2604 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 ELDRHL RPLREV+WG D LLN+TEFAQPALFAVEVAL+RLL SWG+R Sbjct: 2605 VFAEAFNTVVGELDRHLLRPLREVMWGHDENLLNSTEFAQPALFAVEVALFRLLGSWGVR 2664 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P VMGHS+GELSAAHV+G RGRLMQALP GG M AVQA E+E+RPLL Sbjct: 2665 PDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLL 2724 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 +V +AAVNGP S+V+SGA+ AV+ V D+L A GRRV +LAVSHAFHS LM+PM+++F Sbjct: 2725 SAEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFA 2784 Query: 1845 AVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFV 1904 AVA + GRP I VISNVTGQL +D+GSA YW RHIR+AVRFADSV FA +AG +RF+ Sbjct: 2785 AVAAGIAIGRPTIGVISNVTGQLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL 2844 Query: 1905 EVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGC 1964 EVGP+GGL + IEESL V+V + LRKDRPEP DW +V+ Sbjct: 2845 EVGPSGGLVASIEESLPDVAVTTMSALRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG-- 2902 Query: 1965 GGQRVGLPTYAFAHERFWLA 1984 Q V LPTYAF RFWL+ Sbjct: 2903 EAQFVELPTYAFQRRRFWLS 2922 Score = 843 bits (2177), Expect = 0.0 Identities = 469/882 (53%), Positives = 567/882 (64%), Gaps = 15/882 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA DV+ EFP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y R GGFV VADFDP FFGISP EALAMDPQ R+LLE SWEALE AGIDP LRGS+T Sbjct: 92 SYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVGGYGMLAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG TV ATP++F+ FSR RGLA DGRCK +A ADG G+SEG G Sbjct: 212 MAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLVLQRLSDARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH-TPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 VDVVE HGTGT LGDPIEAQALLATYG+D P PLWLGS+KSNMGH+QAAAGVAGVIK Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIK 391 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH+LLPATLH+D PS HVDWS G V+LLT R WPA R RRAGVSSFG+SGTN Sbjct: 392 MVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGISGTN 450 Query: 1532 AHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 1591 AH GP V+ WVVSA++ + + QA RL +VR LD DVG+ Sbjct: 451 AHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGW 509 Query: 1592 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 1651 SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPGQG+Q Sbjct: 510 SL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQ 568 Query: 1652 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPALFAV 1710 WLGMG EL P + L +V+ GA A L+ + QP LFAV Sbjct: 569 WLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPVLFAV 628 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G G M Sbjct: 629 MVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGM 688 Query: 1771 YAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R RR+ V Sbjct: 689 VSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEV 748 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVR 1887 +A HSV +E + + S VTG + ADYW R++R+ V Sbjct: 749 DYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVRQTVL 808 Query: 1888 FADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEPFXXX 1942 F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 809 FDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFL 868 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 +W L G G V LPTYAF RFWL+ Sbjct: 869 LSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 814 bits (2102), Expect = 0.0 Identities = 463/953 (48%), Positives = 596/953 (62%), Gaps = 25/953 (2%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV---IKSVLGGDGSQ 86 ++ D +DLG S+ + + L G+ + ++D P+ + + I++ L G Sbjct: 1985 IDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAG---- 2040 Query: 87 RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 + + +PIA++GMACR+ G V+ +WD L + + ++E+PA R Sbjct: 2041 --LPQEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGW 2098 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 A + D T G F++ V FD FF + P EA MDPQQR+LLE SW AL Sbjct: 2099 DLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEAL 2158 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P L+ S TGVF GV + Y + TG SS+ + R++Y L + Sbjct: 2159 ERAGIDPTGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSVASGRVAYVLGL 2215 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H+A SL SGECDLA+ G V +P V+ F ++P G Sbjct: 2216 EGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDG 2275 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 C+ + RADG+ EG G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN Sbjct: 2276 RCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP 2335 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGS 440 +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS Sbjct: 2336 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGS 2395 Query: 441 IKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAELGLAVVEEFQEWP 499 +K N+GH + AAG+AG+IK VL + R +LLP+ +VP+P++ ++ + ++ + WP Sbjct: 2396 VKSNMGHTQAAAGVAGVIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP 2454 Query: 500 AVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQA 559 A R RRAGVSSFG GTNAH GP V+ WVVSA++ + + QA Sbjct: 2455 AGA-RTRRAGVSSFGISGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQA 2512 Query: 560 GRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVA 619 RL +VR LD DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V Sbjct: 2513 ARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVV 2571 Query: 620 SGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG 679 G A GKTVFVFPGQG+QWLGMG L AGYP ELDRHL RPLREV+WG Sbjct: 2572 RGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWG 2631 Query: 680 ADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXX 739 D LLN+TEFAQPALFAVEVAL+RLL SWG+RP VMGHS+GELSAAHV+G Sbjct: 2632 HDENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAA 2691 Query: 740 XXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVV 799 RGRLMQALP GG M AVQA E+E+RPLL +V +AAVNGP S+V+SGA+ AV+ V Sbjct: 2692 VLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAEVDIAAVNGPASLVISGAQNAVAAV 2751 Query: 800 VDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED 859 D+L A GRRV +LAVSHAFHS LM+PM+++F AVA + GRP I VISNVTGQL +D Sbjct: 2752 ADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTIGVISNVTGQLAGDD 2811 Query: 860 YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTL 919 +GSA YW RHIR+AVRFADSV FA +AG +RF+EVGP+GGL + IEESL V+V + L Sbjct: 2812 FGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVTTMSAL 2871 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 RKDRPEP DW +V+ Q V LPTYAF RFWL+ Sbjct: 2872 RKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS 2922 Score = 565 bits (1457), Expect = e-158 Identities = 360/886 (40%), Positives = 491/886 (55%), Gaps = 26/886 (2%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETI 160 ++EPIA++GM+CRF G V LW +A+ + ++E+P R A D D + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKS 92 Query: 161 Y---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 Y G F++ V FD FF I P EA MDPQ R+LLE SW ALE AGI P L+ S TG Sbjct: 93 YARTGGFVDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATG 152 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ Y L + + TG +SS+ + R++Y L + GP++ +DTACSSSLV Sbjct: 153 VFAGLIVGGYGML----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLV 208 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H+A SL SGECDLA+ G V +P V+ F ++P G C+ + RADG+ E Sbjct: 209 ALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSE 268 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G G++VL+RLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 269 GGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLS 328 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR-QAAKPLMIGSIKPNIGHLEGAAGIAG 456 AE+D VE HGTGT++GD IEA AL +G+ R + +PL +GS+K N+GH + AAG+AG Sbjct: 329 AAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG 388 Query: 457 LIKTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 +IK VL + R +LLP+ +VP+P++ ++ + ++ + WPA R RRAGVSSFG Sbjct: 389 VIKMVLAM-RHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPA-GARTRRAGVSSFGI 446 Query: 516 GGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 GTNAH GP V+ WVVSA++ + + QA RL +VR LD Sbjct: 447 SGTNAHVIIEAVPVVPRREAGWAGP-VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVA 505 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 DVG+SL RS+FEHRAVVVG RD LLAGL E+ + G V G A GKTVFVFPG Sbjct: 506 DVGWSL-AGRSVFEHRAVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKTVFVFPG 564 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-DAELLNTTEFAQPA 694 QG+QWLGMG EL P + L +V+ GA A L+ + QP Sbjct: 565 QGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGAPGLDRVDVVQPV 624 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAV V+L L +S + P V+GHS GE++AA+V+G +R +L+ L G Sbjct: 625 LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLAGLAG 684 Query: 755 GGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G M ++ G + R LL G++VS+A VNGP +VV+SG A+ ++ + + R R Sbjct: 685 PGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTR 744 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 R+ V +A HSV +E + + S VTG + ADYW R++R Sbjct: 745 RIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRLDTAGLDADYWYRNVR 804 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVS-----VVAVPTLRKDRPEP 926 + V F +V A G F+E P L + +EE+ A + + VPTL + Sbjct: 805 QTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGL 864 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 +W L G G V LPTYAF RFWL+ Sbjct: 865 HRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTYAFDKRRFWLS 908 Score = 86.7 bits (213), Expect = 4e-14 Identities = 44/87 (50%), Positives = 58/87 (66%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +AEQ A +L +V H A VLG +D +AF D G SL+AVE+RNRLK+ Sbjct: 1952 RLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSA 2011 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG++LS T FDYPTP +LA ++ + L Sbjct: 2012 TGLSLSPTLIFDYPTPNRLASYIRTEL 2038 Score = 79.0 bits (193), Expect = 8e-12 Identities = 48/114 (42%), Positives = 63/114 (55%), Gaps = 3/114 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL---HHQNRSAPAAAVRTRVRIDEPIAI 1120 TG+ LS T FDYP LA ++ L Q+ SA AA RI I + Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPV 4097 Score = 78.6 bits (192), Expect = 1e-11 Identities = 41/92 (44%), Positives = 55/92 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 3984 RLEGLPEDEQHAVLLDLVRSHIATVLGSASPEAIDPDRAFQELGFDSLTAVEMRNRLKSA 4043 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNP 2113 TG+ LS T FDYP LA ++ L +P Sbjct: 4044 TGLALSPTLIFDYPNSAALAGYMRRELLGSSP 4075 >tr|B2HF44|B2HF44_MYCMM Tax_Id=216594 (pks12)SubName: Full=Polyketide synthase, Pks12;[Mycobacterium marinum] Length = 4187 Score = 1134 bits (2934), Expect = 0.0 Identities = 601/990 (60%), Positives = 707/990 (71%), Gaps = 22/990 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL + EQ A VL +V H A VLG +D +AF + G SL+AVE+RNR+KT+ Sbjct: 1966 RLHGLPEPEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTV 2025 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRT---RVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP LA+++ + L AP T RV D+PIAIVGM CR Sbjct: 2026 TGLSLSPTLIFDYPTPNGLANYIRAEL----AGAPQEVKHTPAVRVTGDDPIAIVGMSCR 2081 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGG+ SP LW ++ + DV+ +FP DRGWD+ LF+PDPD G YTR GGFV V D Sbjct: 2082 YPGGIESPDDLWDMLMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGD 2141 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 FDP FFG+ P EALAMDPQQR+ LE SWEALE AGI+P LRGS+TGVF G+ GYG+ Sbjct: 2142 FDPAFFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYGMF 2201 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2202 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDL 2261 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG T+ ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLV++RLSDA+R Sbjct: 2262 ALAGGVTINATPDIFVEFSRWRGLSADGRCKAFAGAADGTGFSEGGGMLVVERLSDAQRL 2321 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2322 GHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2381 Query: 1426 GDPIEAQALLATYGRDH----TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLL 1481 GDPIEAQALLATYG+D LWLGSIKSNMGH+QAAAGVAGVIKMV+AMRH++L Sbjct: 2382 GDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVL 2441 Query: 1482 PATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVG--RPRRAGVSSFGVSGTNAHXXXXXX 1539 PATLH+D PS HVDWS G V+LLTEA+ WPA R RRAGVSSFG+SGTNAH Sbjct: 2442 PATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAA 2501 Query: 1540 XXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 1599 V+ WVVSA++ + +GAQA RL VR+ ELD DVG+SL RS Sbjct: 2502 PRVEVGGSSGGAVPVVPWVVSAKSGSALGAQAARLAAHVRSHDELDVADVGWSLAG-RST 2560 Query: 1600 FEHRAVVVGAGRDELLAGLAEVVEGR-PGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRE 1658 FEHRAVV+G RD LLAGL E+ G V GVA GKTVFVFPGQG+Q LGMG Sbjct: 2561 FEHRAVVLGVDRDGLLAGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMG 2620 Query: 1659 LCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLL 1718 L AGYP ELDRHL RPLREV+WG D LLNTTEFAQPALFAVEVALYRLL Sbjct: 2621 LHAGYPVFAEAFNTVVGELDRHLLRPLREVIWGHDENLLNTTEFAQPALFAVEVALYRLL 2680 Query: 1719 ESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQ 1778 ESWG+RP VMGHSVGELSAAHV+G RGRLMQALP GG M AVQA EQ Sbjct: 2681 ESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLMQALPDGGAMIAVQATEQ 2740 Query: 1779 ELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEP 1838 E+ PLLG QVS+AA+NGP SVV+SGA++AVS V ++L A GRRV RLAVSHAFHS LM+P Sbjct: 2741 EVLPLLGAQVSIAAINGPASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDP 2800 Query: 1839 MLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSA 1898 M+++F VA E+ P I +ISN+TGQL ED+GSA YW RH+R+AVRFADS+ FA SA Sbjct: 2801 MIDEFATVAGELTVNAPTIGIISNLTGQLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSA 2860 Query: 1899 GATRFVEVGPAGGLTSLIEESLAQVS----VVAVPTLRKDRPEPFXXXXXXXXXXXXXXX 1954 GA RF+EVGP+ GLT+ IEE L+ + V LRKDRPEP Sbjct: 2861 GAARFLEVGPSSGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSAVAGVFVAGTA 2920 Query: 1955 XDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 DW +V+ V LPTYAF RFWL+ Sbjct: 2921 VDWRAVVG--QSNFVELPTYAFERRRFWLS 2948 Score = 844 bits (2180), Expect = 0.0 Identities = 471/889 (52%), Positives = 581/889 (65%), Gaps = 20/889 (2%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA G DV+ +FP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y GGFV VADFDPGFFGI+P EALAMDPQ R+LLE SWEALE +GIDP LRGS+T Sbjct: 92 SYASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVQGYGMFAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG+TV ATP++F+ FSR RGLA DGR KA+A AADG G+SEG Sbjct: 212 MAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRSKAYAGAADGVGWSEGGA 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLV++RLSDA+R G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH----TPDAPLWLGSIKSNMGHSQAAAGVAG 1468 VDVVE HGTGT LGDPIEAQALLATYG+D LWLGSIKSNMGH+QAAAGVAG Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAG 391 Query: 1469 VIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPA--VVGRPRRAGVSSFG 1526 VIKMV+AMRH++LPATLH+D PS HVDWS G V+LLTEA+ WPA R RRAGVSSFG Sbjct: 392 VIKMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFG 451 Query: 1527 VSGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 1586 +SGTNAH V+ WVVSA++ + +GAQA RL VR+ ELD Sbjct: 452 ISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSALGAQAARLAAHVRSHDELDV 511 Query: 1587 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVV-EGRPGVGVASGVAMPGGKTVFVF 1645 DVG+SL RS FEHRAVV+G RD LLAGL E+ + G V GVA GKTVFVF Sbjct: 512 ADVGWSL-AGRSTFEHRAVVLGVDRDGLLAGLDELAGDEFGGASVIRGVAGAAGKTVFVF 570 Query: 1646 PGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG-ADAELLNTTEFAQ 1704 PGQG+QW+GMG EL P + L +V+ G A A L+ + Q Sbjct: 571 PGQGSQWIGMGIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGAPGLDRVDVVQ 630 Query: 1705 PALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQAL 1764 P LFAV V+L L +S G+RP V+GHS GE++AA+V+G +R +L+ L Sbjct: 631 PVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLRSKLLVGL 690 Query: 1765 PGGGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRR 1821 G G M +V GEQ+ R LL G++VS+AA+NGP +VV+SG A+ ++ + A + R Sbjct: 691 AGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGEVAALEELIAQCADRELR 750 Query: 1822 VRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRH 1881 RR+ V +A HSV +E + Q V + S+VTG + A+YW R+ Sbjct: 751 TRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLSSRTAFFSSVTGSRLDTAELDAEYWYRN 810 Query: 1882 IREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV------VAVPTLRKDR 1935 IR+ V+F +V A G F+E P L + IE++ + + VPTL ++ Sbjct: 811 IRQTVQFDQAVRSACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGRED 870 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 DW L G G V LPTYAF RFWL+ Sbjct: 871 GGLQRFLASAAAAFVAGVNVDWRGPLDGAG--LVELPTYAFEKRRFWLS 917 Score = 800 bits (2065), Expect = 0.0 Identities = 462/973 (47%), Positives = 595/973 (61%), Gaps = 28/973 (2%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVI 76 +IA G + E ++ D ++LG S+ + + + V G+ + ++D P+ + + Sbjct: 1986 HIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLA 2045 Query: 77 KSVLGG-DGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKS 135 + G+ + V G+ +PIA++GM+CR+ G + LWD L ++ Sbjct: 2046 NYIRAELAGAPQEVKHTPAVRVTGD----DPIAIVGMSCRYPGGIESPDDLWDMLMARRD 2101 Query: 136 AITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQ 190 ++++PA R A + D T G F++ V FD FF + P EA MDPQQ Sbjct: 2102 VLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFDPAFFGVGPSEALAMDPQQ 2161 Query: 191 RLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSI 250 R+ LE SW ALE AGI P L+ S TGVF GV + Y + TG SS+ Sbjct: 2162 RMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSV 2218 Query: 251 IANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRG 310 + R++Y L + GP++ +DTACSSSLVA H+A +SL SGECDLA+ G + +P+++ Sbjct: 2219 ASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVE 2278 Query: 311 FQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDG 370 F +S G C+AF ADG EG G++V+ERLSDA+R G VLA++ GSAVNQDG Sbjct: 2279 FSRWRGLSADGRCKAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDG 2338 Query: 371 RSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR 430 SNG+ APN +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R Sbjct: 2339 ASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDR 2398 Query: 431 QAA----KPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAE 486 +A K L +GSIK N+GH + AAG+AG+IK V ++ L + +VP+P++ ++ Sbjct: 2399 GSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSA 2458 Query: 487 LGLAVVEEFQEWPAVVG--RPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLA 544 + ++ E Q WPA R RRAGVSSFG GTNAH V+ Sbjct: 2459 GAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVP 2518 Query: 545 WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLA 604 WVVSA++ + +GAQA RL VR+ ELD DVG+SL RS FEHRAVV+G RD LLA Sbjct: 2519 WVVSAKSGSALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGVDRDGLLA 2577 Query: 605 GLAEVVEGR-PGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXX 663 GL E+ G V GVA GKTVFVFPGQG+Q LGMG L AGYP Sbjct: 2578 GLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAEAFNTVVG 2637 Query: 664 ELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGE 723 ELDRHL RPLREV+WG D LLNTTEFAQPALFAVEVALYRLLESWG+RP VMGHSVGE Sbjct: 2638 ELDRHLLRPLREVIWGHDENLLNTTEFAQPALFAVEVALYRLLESWGVRPDFVMGHSVGE 2697 Query: 724 LSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNG 783 LSAAHV+G RGRLMQALP GG M AVQA EQE+ PLLG QVS+AA+NG Sbjct: 2698 LSAAHVAGVLSLENAAVLVAARGRLMQALPDGGAMIAVQATEQEVLPLLGAQVSIAAING 2757 Query: 784 PGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRP 843 P SVV+SGA++AVS V ++L A GRRV RLAVSHAFHS LM+PM+++F VA E+ P Sbjct: 2758 PASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAP 2817 Query: 844 AIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSL 903 I +ISN+TGQL ED+GSA YW RH+R+AVRFADS+ FA SAGA RF+EVGP+ GLT+ Sbjct: 2818 TIGIISNLTGQLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEVGPSSGLTAS 2877 Query: 904 IEESLAQVS----VVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGL 959 IEE L+ + V LRKDRPEP DW +V+ V L Sbjct: 2878 IEEVLSDAAVTNPVATASALRKDRPEPVSLVSAVAGVFVAGTAVDWRAVVG--QSNFVEL 2935 Query: 960 PTYAFAHERFWLA 972 PTYAF RFWL+ Sbjct: 2936 PTYAFERRRFWLS 2948 Score = 569 bits (1466), Expect = e-159 Identities = 362/893 (40%), Positives = 498/893 (55%), Gaps = 31/893 (3%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIY- 161 ++EPIA++GM+CRF G V LW +AE + ++++P R G AD + +T + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVAEGRDVMSDFPTDR-GWDLADLFDPDPDTPHK 91 Query: 162 -----GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHT 216 G F++ V FD FF I P EA MDPQ R+LLE SW ALE +GI P L+ S T Sbjct: 92 SYASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGSAT 151 Query: 217 GVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSL 276 GVF G+ Y + + TG +SS+ + R++Y L + GP++ +DTACSSSL Sbjct: 152 GVFAGLIVQGYGMF----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSL 207 Query: 277 VAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRG 336 VA H+A +SL SGECDLA+ G V +P V+ F ++P G +A+ ADG+ Sbjct: 208 VALHMAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRSKAYAGAADGVGWS 267 Query: 337 EGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADI 396 EG ++V+ERLSDA+R G VLA++ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 268 EGGAMLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGL 327 Query: 397 DPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR----QAAKPLMIGSIKPNIGHLEGAA 452 AE+D VE HGTGT++GD IEA AL +G+ R A K L +GSIK N+GH + AA Sbjct: 328 SAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAA 387 Query: 453 GIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPA--VVGRPRRAGV 510 G+AG+IK V ++ L + +VP+P++ ++ + ++ E Q WPA R RRAGV Sbjct: 388 GVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGV 447 Query: 511 SSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGR 570 SSFG GTNAH V+ WVVSA++ + +GAQA RL VR+ Sbjct: 448 SSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSALGAQAARLAAHVRSHD 507 Query: 571 ELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVV-EGRPGVGVASGVAMPGGKT 629 ELD DVG+SL RS FEHRAVV+G RD LLAGL E+ + G V GVA GKT Sbjct: 508 ELDVADVGWSL-AGRSTFEHRAVVLGVDRDGLLAGLDELAGDEFGGASVIRGVAGAAGKT 566 Query: 630 VFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG-ADAELLNTT 688 VFVFPGQG+QW+GMG EL P + L +V+ G A A L+ Sbjct: 567 VFVFPGQGSQWIGMGIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGAPGLDRV 626 Query: 689 EFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRL 748 + QP LFAV V+L L +S G+RP V+GHS GE++AA+V+G +R +L Sbjct: 627 DVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLRSKL 686 Query: 749 MQALPGGGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAA 805 + L G G M +V GEQ+ R LL G++VS+AA+NGP +VV+SG A+ ++ + A Sbjct: 687 LVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGEVAALEELIAQCAD 746 Query: 806 QGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADY 865 + R RR+ V +A HSV +E + Q V + S+VTG + A+Y Sbjct: 747 RELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLSSRTAFFSSVTGSRLDTAELDAEY 806 Query: 866 WVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV------VAVPTL 919 W R+IR+ V+F +V A G F+E P L + IE++ + + VPTL Sbjct: 807 WYRNIRQTVQFDQAVRSACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTL 866 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 ++ DW L G G V LPTYAF RFWL+ Sbjct: 867 GREDGGLQRFLASAAAAFVAGVNVDWRGPLDGAG--LVELPTYAFEKRRFWLS 917 Score = 85.5 bits (210), Expect = 9e-14 Identities = 47/105 (44%), Positives = 64/105 (60%), Gaps = 5/105 (4%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL + EQ A VL +V H A VLG +D +AF + G SL+AVE+RNR+KT+ Sbjct: 1966 RLHGLPEPEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTV 2025 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDAL 2126 TG++LS T FDYPTP LA+++ + L GA E+ A+ Sbjct: 2026 TGLSLSPTLIFDYPTPNGLANYIRAEL-----AGAPQEVKHTPAV 2065 Score = 82.8 bits (203), Expect = 6e-13 Identities = 44/100 (44%), Positives = 60/100 (60%), Gaps = 5/100 (5%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 4019 RLEGLPEDEQHAILLNLVRSHIATVLGNSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSA 4078 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELD 2121 TG+ LS T FDYP LA ++ H+ GA+P+ D Sbjct: 4079 TGLALSPTLIFDYPNSAALAGYM-----HRELVGASPQSD 4113 Score = 77.4 bits (189), Expect = 2e-11 Identities = 39/83 (46%), Positives = 52/83 (62%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 4019 RLEGLPEDEQHAILLNLVRSHIATVLGNSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSA 4078 Query: 1070 TGVTLSATTAFDYPTPTQLADHL 1092 TG+ LS T FDYP LA ++ Sbjct: 4079 TGLALSPTLIFDYPNSAALAGYM 4101 >tr|A0PQM7|A0PQM7_MYCUA Tax_Id=362242 (pks12)SubName: Full=Polyketide synthase, Pks12;[Mycobacterium ulcerans] Length = 4191 Score = 1131 bits (2926), Expect = 0.0 Identities = 600/990 (60%), Positives = 707/990 (71%), Gaps = 22/990 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL + EQ A VL +V H A VLG +D +AF + G SL+AVE+RNR+KT+ Sbjct: 1970 RLHGLPELEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTV 2029 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRT---RVRIDEPIAIVGMGCR 1126 TG++LS T FDYPTP LA+++ + L AP T RV D+PIAIVGM CR Sbjct: 2030 TGLSLSPTLIFDYPTPNGLANYIRAEL----AGAPQEVKHTPAVRVTGDDPIAIVGMSCR 2085 Query: 1127 YPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVAD 1186 YPGG+ SP LW ++ + DV+ +FP DRGWD+ LF+PDPD G YTR GGFV V D Sbjct: 2086 YPGGIESPDDLWDMLMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGD 2145 Query: 1187 FDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG 1246 F+P FFG+ P EALAMDPQQR+ LE SWEALE AGI+P LRGS+TGVF G+ GYG+ Sbjct: 2146 FEPAFFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYGMF 2205 Query: 1247 TSQ-AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 ++ + + TG ++SVASGR++Y LGL GPA+SVDTACSSSLVALH+A SLR+GECDL Sbjct: 2206 AAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDL 2265 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG T+ ATP IF+ FSR RGL+ DGRCKAFA AADGTGFSEG GMLV++RLSDA+R Sbjct: 2266 ALAGGVTINATPDIFVEFSRWRGLSADGRCKAFAGAADGTGFSEGGGMLVVERLSDAQRL 2325 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+VDVVE HGTGT L Sbjct: 2326 GHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL 2385 Query: 1426 GDPIEAQALLATYGRDH----TPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLL 1481 GDPIEAQALLATYG+D LWLGSIKSNMGH+QAAAGVAGVIKMV+AMRH++L Sbjct: 2386 GDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVL 2445 Query: 1482 PATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVG--RPRRAGVSSFGVSGTNAHXXXXXX 1539 PATLH+D PS HVDWS G V+LLTEA+ WPA R RRAGVSSFG+SGTNAH Sbjct: 2446 PATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAA 2505 Query: 1540 XXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 1599 V+ WVVSA++ + +GAQA RL VR+ ELD DVG+SL RS Sbjct: 2506 PRVEVGGSSGGAVPVVPWVVSAKSGSALGAQAARLAAHVRSHDELDVADVGWSLAG-RST 2564 Query: 1600 FEHRAVVVGAGRDELLAGLAEVVEGR-PGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRE 1658 FEHRAVV+GA RD LLAGL E+ G V GVA GKTVFVFPGQG+Q LGMG Sbjct: 2565 FEHRAVVLGADRDGLLAGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMG 2624 Query: 1659 LCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLL 1718 L AGYP ELDRHL RPLREV+WG D LLNTTEFAQPALFAVEVALYRLL Sbjct: 2625 LHAGYPVFAEAFNTVVGELDRHLLRPLREVIWGHDENLLNTTEFAQPALFAVEVALYRLL 2684 Query: 1719 ESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQ 1778 ESWG+RP VMGHSVGELSAAHV+G RGRLMQALP GG M AVQA EQ Sbjct: 2685 ESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLMQALPDGGAMIAVQATEQ 2744 Query: 1779 ELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEP 1838 E+ PLLG QVS+A +NGP SVV+SGA++AVS V ++L A GRRV RLAVSHAFHS LM+P Sbjct: 2745 EVLPLLGAQVSIATINGPASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDP 2804 Query: 1839 MLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSA 1898 M+++F VA E+ P I +ISN+TGQL ED+GSA YW RH+R+AVRFADS+ FA SA Sbjct: 2805 MIDEFATVAGELTVNAPTIGIISNLTGQLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSA 2864 Query: 1899 GATRFVEVGPAGGLTSLIEESLAQVS----VVAVPTLRKDRPEPFXXXXXXXXXXXXXXX 1954 GA RF+EVGP+ GLT+ IEE L+ + V LRKDRPEP Sbjct: 2865 GAARFLEVGPSIGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSALAGVFVAGTA 2924 Query: 1955 XDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 DW +V+ V LPTYAF RFWL+ Sbjct: 2925 VDWRAVVG--QSHFVELPTYAFERRRFWLS 2952 Score = 845 bits (2183), Expect = 0.0 Identities = 472/889 (53%), Positives = 582/889 (65%), Gaps = 20/889 (2%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EPIAIVGM CR+PGGV SP LWQ+VA G DV+ +FP DRGWD+ LFDPDPD K Sbjct: 32 RSSEPIAIVGMSCRFPGGVDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHK 91 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 +Y GGFV VADFDPGFFGI+P EALAMDPQ R+LLE SWEALE +GIDP LRGS+T Sbjct: 92 SYASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGSAT 151 Query: 1233 GVFVGIYGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALH 1292 GVF G+ GYG+ + + Y TG +SVASGR++Y LGL GPA+SVDTACSSSLVALH Sbjct: 152 GVFAGLIVQGYGMFAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH 211 Query: 1293 LAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAG 1352 +A SLR+GECDLALAGG+TV ATP++F+ FSR RGLA DGR KA+A AADG G+SEG Sbjct: 212 MAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRSKAYAGAADGVGWSEGGA 271 Query: 1353 MLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGAD 1412 MLV++RLSDA+R G PVLA++ GSAVNQDGASNGLTAP+GP+QQRV+ AAL++AG++ A+ Sbjct: 272 MLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAE 331 Query: 1413 VDVVEAHGTGTRLGDPIEAQALLATYGRDH----TPDAPLWLGSIKSNMGHSQAAAGVAG 1468 VDVVE HGTGT LGDPIEAQALLATYG+D LWLGSIKSNMGH+QAAAGVAG Sbjct: 332 VDVVEGHGTGTTLGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAG 391 Query: 1469 VIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPA--VVGRPRRAGVSSFG 1526 VIKMV+AMRH++LPATLH+D PS HVDWS G V+LLTEA+ WPA R RRAGVSSFG Sbjct: 392 VIKMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFG 451 Query: 1527 VSGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 1586 +SGTNAH V+ WVVSA++ + +GAQA RL VR+ ELD Sbjct: 452 ISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSALGAQAARLAAHVRSHDELDV 511 Query: 1587 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVV-EGRPGVGVASGVAMPGGKTVFVF 1645 DVG+SL RS FEHRAVV+GA RD LLAGL E+ + G V GVA GKTVFVF Sbjct: 512 ADVGWSL-AGRSTFEHRAVVLGADRDGLLAGLDELAGDEFGGASVIRGVAGAAGKTVFVF 570 Query: 1646 PGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG-ADAELLNTTEFAQ 1704 PGQG+QW+GMG EL P + L +V+ G A A L+ + Q Sbjct: 571 PGQGSQWIGMGIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGAPGLDRIDVVQ 630 Query: 1705 PALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQAL 1764 P LFAV V+L L +S G+RP V+GHS GE++AA+V+G +R +L+ L Sbjct: 631 PVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLRSKLLVGL 690 Query: 1765 PGGGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRR 1821 G G M +V GEQ+ R LL G++VS+AA+NGP +VV+SG A+ ++ + A + R Sbjct: 691 AGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGEVAALEELIAQCADRELR 750 Query: 1822 VRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRH 1881 RR+ V +A HSV +E + Q V + S+VTG + A+YW R+ Sbjct: 751 TRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLSSRTAFFSSVTGSRLDTAELDAEYWYRN 810 Query: 1882 IREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV------VAVPTLRKDR 1935 IR+ V+F +V A G F+E P L + IE++ + + VPTL ++ Sbjct: 811 IRQTVQFDQAVRSACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGRED 870 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 DW L G G V LPTYAF RFWL+ Sbjct: 871 GGLQRFLASAAAAFVAGVNVDWRGPLDGAG--LVELPTYAFEKRRFWLS 917 Score = 796 bits (2057), Expect = 0.0 Identities = 461/973 (47%), Positives = 595/973 (61%), Gaps = 28/973 (2%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVI 76 +IA G + E ++ D ++LG S+ + + + V G+ + ++D P+ + + Sbjct: 1990 HIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLA 2049 Query: 77 KSVLGG-DGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKS 135 + G+ + V G+ +PIA++GM+CR+ G + LWD L ++ Sbjct: 2050 NYIRAELAGAPQEVKHTPAVRVTGD----DPIAIVGMSCRYPGGIESPDDLWDMLMARRD 2105 Query: 136 AITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQ 190 ++++PA R A + D T G F++ V F+ FF + P EA MDPQQ Sbjct: 2106 VLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFEPAFFGVGPSEALAMDPQQ 2165 Query: 191 RLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSI 250 R+ LE SW ALE AGI P L+ S TGVF GV + Y + TG SS+ Sbjct: 2166 RMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYGMF---AAEPVEGFRLTGQLSSV 2222 Query: 251 IANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRG 310 + R++Y L + GP++ +DTACSSSLVA H+A +SL SGECDLA+ G + +P+++ Sbjct: 2223 ASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVE 2282 Query: 311 FQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDG 370 F +S G C+AF ADG EG G++V+ERLSDA+R G VLA++ GSAVNQDG Sbjct: 2283 FSRWRGLSADGRCKAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDG 2342 Query: 371 RSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR 430 SNG+ APN +Q V+ +A A + AE+D VE HGTGT++GD IEA AL +G+ R Sbjct: 2343 ASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDR 2402 Query: 431 QAA----KPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAE 486 +A K L +GSIK N+GH + AAG+AG+IK V ++ L + +VP+P++ ++ Sbjct: 2403 GSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSA 2462 Query: 487 LGLAVVEEFQEWPAVVG--RPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLA 544 + ++ E Q WPA R RRAGVSSFG GTNAH V+ Sbjct: 2463 GAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVP 2522 Query: 545 WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLA 604 WVVSA++ + +GAQA RL VR+ ELD DVG+SL RS FEHRAVV+GA RD LLA Sbjct: 2523 WVVSAKSGSALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGADRDGLLA 2581 Query: 605 GLAEVVEGR-PGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXX 663 GL E+ G V GVA GKTVFVFPGQG+Q LGMG L AGYP Sbjct: 2582 GLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAEAFNTVVG 2641 Query: 664 ELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGE 723 ELDRHL RPLREV+WG D LLNTTEFAQPALFAVEVALYRLLESWG+RP VMGHSVGE Sbjct: 2642 ELDRHLLRPLREVIWGHDENLLNTTEFAQPALFAVEVALYRLLESWGVRPDFVMGHSVGE 2701 Query: 724 LSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNG 783 LSAAHV+G RGRLMQALP GG M AVQA EQE+ PLLG QVS+A +NG Sbjct: 2702 LSAAHVAGVLSLENAAVLVAARGRLMQALPDGGAMIAVQATEQEVLPLLGAQVSIATING 2761 Query: 784 PGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRP 843 P SVV+SGA++AVS V ++L A GRRV RLAVSHAFHS LM+PM+++F VA E+ P Sbjct: 2762 PASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAP 2821 Query: 844 AIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSL 903 I +ISN+TGQL ED+GSA YW RH+R+AVRFADS+ FA SAGA RF+EVGP+ GLT+ Sbjct: 2822 TIGIISNLTGQLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEVGPSIGLTAS 2881 Query: 904 IEESLAQVS----VVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGL 959 IEE L+ + V LRKDRPEP DW +V+ V L Sbjct: 2882 IEEVLSDAAVTNPVATASALRKDRPEPVSLVSALAGVFVAGTAVDWRAVVG--QSHFVEL 2939 Query: 960 PTYAFAHERFWLA 972 PTYAF RFWL+ Sbjct: 2940 PTYAFERRRFWLS 2952 Score = 570 bits (1469), Expect = e-160 Identities = 363/893 (40%), Positives = 499/893 (55%), Gaps = 31/893 (3%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIY- 161 ++EPIA++GM+CRF G V LW +AE + ++++P R G AD + +T + Sbjct: 33 SSEPIAIVGMSCRFPGGVDSPEGLWQMVAEGRDVMSDFPTDR-GWDLADLFDPDPDTPHK 91 Query: 162 -----GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHT 216 G F++ V FD FF I P EA MDPQ R+LLE SW ALE +GI P L+ S T Sbjct: 92 SYASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGSAT 151 Query: 217 GVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSL 276 GVF G+ Y + + TG +SS+ + R++Y L + GP++ +DTACSSSL Sbjct: 152 GVFAGLIVQGYGMF----AEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSL 207 Query: 277 VAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRG 336 VA H+A +SL SGECDLA+ G V +P V+ F ++P G +A+ ADG+ Sbjct: 208 VALHMAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRSKAYAGAADGVGWS 267 Query: 337 EGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADI 396 EG ++V+ERLSDA+R G VLA++ GSAVNQDG SNG+ APN +Q V+ +A A + Sbjct: 268 EGGAMLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGL 327 Query: 397 DPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGR----QAAKPLMIGSIKPNIGHLEGAA 452 AE+D VE HGTGT++GD IEA AL +G+ R A K L +GSIK N+GH + AA Sbjct: 328 SAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAA 387 Query: 453 GIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPA--VVGRPRRAGV 510 G+AG+IK V ++ L + +VP+P++ ++ + ++ E Q WPA R RRAGV Sbjct: 388 GVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGV 447 Query: 511 SSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGR 570 SSFG GTNAH V+ WVVSA++ + +GAQA RL VR+ Sbjct: 448 SSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSALGAQAARLAAHVRSHD 507 Query: 571 ELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVV-EGRPGVGVASGVAMPGGKT 629 ELD DVG+SL RS FEHRAVV+GA RD LLAGL E+ + G V GVA GKT Sbjct: 508 ELDVADVGWSL-AGRSTFEHRAVVLGADRDGLLAGLDELAGDEFGGASVIRGVAGAAGKT 566 Query: 630 VFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG-ADAELLNTT 688 VFVFPGQG+QW+GMG EL P + L +V+ G A A L+ Sbjct: 567 VFVFPGQGSQWIGMGIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGAPGLDRI 626 Query: 689 EFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRL 748 + QP LFAV V+L L +S G+RP V+GHS GE++AA+V+G +R +L Sbjct: 627 DVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLRSKL 686 Query: 749 MQALPGGGVMYAVQAGEQELRPLL---GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAA 805 + L G G M +V GEQ+ R LL G++VS+AA+NGP +VV+SG A+ ++ + A Sbjct: 687 LVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGEVAALEELIAQCAD 746 Query: 806 QGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADY 865 + R RR+ V +A HSV +E + Q V + S+VTG + A+Y Sbjct: 747 RELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLSSRTAFFSSVTGSRLDTAELDAEY 806 Query: 866 WVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV------VAVPTL 919 W R+IR+ V+F +V A G F+E P L + IE++ + + VPTL Sbjct: 807 WYRNIRQTVQFDQAVRSACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTL 866 Query: 920 RKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 ++ DW L G G V LPTYAF RFWL+ Sbjct: 867 GREDGGLQRFLASAAAAFVAGVNVDWRGPLDGAG--LVELPTYAFEKRRFWLS 917 Score = 85.5 bits (210), Expect = 9e-14 Identities = 47/105 (44%), Positives = 64/105 (60%), Gaps = 5/105 (4%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL + EQ A VL +V H A VLG +D +AF + G SL+AVE+RNR+KT+ Sbjct: 1970 RLHGLPELEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTV 2029 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDAL 2126 TG++LS T FDYPTP LA+++ + L GA E+ A+ Sbjct: 2030 TGLSLSPTLIFDYPTPNGLANYIRAEL-----AGAPQEVKHTPAV 2069 Score = 82.8 bits (203), Expect = 6e-13 Identities = 44/100 (44%), Positives = 60/100 (60%), Gaps = 5/100 (5%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 4023 RLEGLPEDEQHAILLNLVRSHIATVLGNSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSA 4082 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELD 2121 TG+ LS T FDYP LA ++ H+ GA+P+ D Sbjct: 4083 TGLALSPTLIFDYPNSAALAGYM-----HRELVGASPQSD 4117 Score = 77.4 bits (189), Expect = 2e-11 Identities = 39/83 (46%), Positives = 52/83 (62%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+GL + EQ A +L +V H A VLG +D +AF + G SL+AVE+RNRLK+ Sbjct: 4023 RLEGLPEDEQHAILLNLVRSHIATVLGNSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSA 4082 Query: 1070 TGVTLSATTAFDYPTPTQLADHL 1092 TG+ LS T FDYP LA ++ Sbjct: 4083 TGLALSPTLIFDYPNSAALAGYM 4105 >tr|C0Z475|C0Z475_STRVN Tax_Id=1935 (ken14)SubName: Full=Type I polyketide synthase, modules 7-8;[Streptomyces violaceoruber] Length = 3447 Score = 1100 bits (2844), Expect = 0.0 Identities = 661/1442 (45%), Positives = 829/1442 (57%), Gaps = 59/1442 (4%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL+ A+ + ++L +V H AAVLG A ++A + F +AG SL+AVELRNRL T Sbjct: 2003 RLAGLAAADAERSLLDLVRTHVAAVLGHASADDVEALRTFKEAGFDSLTAVELRNRLTTA 2062 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQN----RSAPAAAVRTRVRIDEPIAIVGMGC 1125 TG+ L AT FD+PTP LADHL++ L Q + P A V D+P+ IV C Sbjct: 2063 TGLRLPATLVFDHPTPQALADHLVARLLEQRGETVTTQPPAPVAAAPSSDDPVVIVAASC 2122 Query: 1126 RYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVA 1185 R+PGGV SP LW LVA G I +FP DRGWDI+ L+D DP G+TYTR GGF+ +VA Sbjct: 2123 RFPGGVGSPEDLWDLVADGRHGISDFPADRGWDIDALYDADPGRRGRTYTRSGGFLGEVA 2182 Query: 1186 DFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGY-- 1243 +FDP FGISP EALAMDPQQRLLLETSWEA E AGIDP +LRGS TGVFVG G Y Sbjct: 2183 EFDPSLFGISPREALAMDPQQRLLLETSWEAFERAGIDPGSLRGSGTGVFVGASGADYVS 2242 Query: 1244 -GLGT-SQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAG 1301 G G + + Y G SVASGR+SY GL GPA++VDTACSS+LVALHLAA SLR G Sbjct: 2243 LGAGAPEEVEGYLGIGSAGSVASGRLSYTFGLEGPAVTVDTACSSALVALHLAAQSLRQG 2302 Query: 1302 ECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSD 1361 ECDLALA G TV+ATPS+F+ FSRQRGL+ DG+CKAFADAADG GF+EGAG L+L+RLSD Sbjct: 2303 ECDLALAAGVTVMATPSLFVEFSRQRGLSPDGQCKAFADAADGAGFAEGAGTLLLERLSD 2362 Query: 1362 ARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGT 1421 ARR G VLA++ GSAVNQDGASNGLTAP+GP+Q+RVI AL++A +T DVDVVEAHGT Sbjct: 2363 ARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQERVIRQALANARLTPGDVDVVEAHGT 2422 Query: 1422 GTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLL 1481 GTRLGDPIEAQALLATYG+D PLWLGS+KSN+GH+QAAAG AGVIKMV A++H+ L Sbjct: 2423 GTRLGDPIEAQALLATYGQDRAGGEPLWLGSVKSNIGHTQAAAGAAGVIKMVMALQHEAL 2482 Query: 1482 PATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH-----XXX 1536 P TLH+D P++HVDWS G V+LLTE R+WP R RR GVSSFG+SGTNAH Sbjct: 2483 PRTLHVDAPTSHVDWSAGAVELLTEGRDWPRTEHRVRRVGVSSFGISGTNAHVVLEEAPV 2542 Query: 1537 XXXXXXXXXXXXXXGPGVLA-WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVT 1595 GV A W++SA T V AQA RL + + A +L A DVGY+L Sbjct: 2543 LRSVASEAPEAKGEETGVPAPWILSAATEEAVRAQARRLHDHLAARPDLTARDVGYALAR 2602 Query: 1596 TRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPG---GKTVFVFPGQGAQW 1652 R+ EH AVVVG GR++LLA A++ G A+ + PG G T F+F GQG+Q Sbjct: 2603 HRARLEHTAVVVGHGREQLLAACADLASGT--YTAAATLVRPGQPQGGTAFLFTGQGSQR 2660 Query: 1653 LGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG------ADAELLNTTEFAQPA 1706 GMG EL A +P LD HL RPLR++++ A A LL+ TE+ QPA Sbjct: 2661 PGMGGELHAAFPVFADALDETCAHLDPHLDRPLRDLMFAGPGSDEAAAALLDRTEYTQPA 2720 Query: 1707 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 1766 LFA EVALYR +WG+RP ++GHSVGEL+AAHV+G RGRLM ALP Sbjct: 2721 LFAFEVALYRQFTAWGVRPDFLIGHSVGELAAAHVAGVLPLADAAALIAARGRLMGALPP 2780 Query: 1767 GGVMYAVQAGEQELRPLL------GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGR 1820 GG M +V+AGE E+ L+ G+++ +AAVNGP + V+SG +AV + + +G Sbjct: 2781 GGAMLSVRAGETEVAELVAQEDESGQRLGIAAVNGPAATVVSGDEDAVLRLAETARGRGW 2840 Query: 1821 RVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAE-DYGSADYWV 1879 + RL VSHAFHS M+ +L+ FR VA + P IPV+SN+TG+ V + YWV Sbjct: 2841 KTARLRVSHAFHSPHMDAVLDDFRQVASGLSYAEPTIPVVSNLTGEPVGRGEMSGPGYWV 2900 Query: 1880 RHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV-----VAVPTLRKD 1934 RH REAVRF D V H AG RFVE+GP L+++ +ES+ + +P R+ Sbjct: 2901 RHAREAVRFHDGVRRLHRAGVRRFVEIGPDAVLSTMAQESVGGEAPRRDRRAFLPVQRRT 2960 Query: 1935 RPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL----ADRFXXX 1990 R E DWA+VL + LPTYAF +R+WL A Sbjct: 2961 RGEAASLVSAVAQVHAWHGSVDWAAVLP--AARAAELPTYAFQRQRYWLDPAPAGAVPGH 3018 Query: 1991 XXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRD 2050 RL GL AE+ AAVLA+V + A +LG Sbjct: 3019 ALGPIAGAAARTAVAGVDGPPGASHAPDRGARLLGLPAAERPAAVLALVRDSAAGILGHP 3078 Query: 2051 GAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHH 2110 A +D + + G SL+AVELR+ L + TG L T FD+PT +A+HLL+ L Sbjct: 3079 SADAVDPDRELLELGFDSLTAVELRDHLASATGTDLPTTLLFDHPTCADIAEHLLTRLSA 3138 Query: 2111 QNPTGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVL 2170 TG + DL+ DAG + ++ A R R + Sbjct: 3139 DGATGPAD-----SGIADLYWSANDAGHYEAATGLLRAVAALRPAFDEDTADRHAPRPLR 3193 Query: 2171 LAGGRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVL 2230 LA G + A+VCLP+ + S PH Y A A+ G V AL PGF ALP D + ++ Sbjct: 3194 LARGDARPALVCLPSFSPASGPHEYARFAAALRGDREVWALPEPGFLDGQALPADVDALV 3253 Query: 2231 EGAAQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVN 2290 A A L G VL G S+ G +AHAL + L E R + L+DTY P + Sbjct: 3254 AAHAHA-LATDGPGTAPVLVGRSAAGWIAHALAARL-EAEGRPAAALVLLDTYSPDALAR 3311 Query: 2291 ADNPDQVGVNETGALFSRRVTSMARELDQLNXXXXXXXXXXXXXFGTWEPVVSAVPLLNM 2350 D V T A R + R N F W P P L + Sbjct: 3312 R---DWVRTAMTRATSGRESALVLR-----NETRLAATGGYDRIFTGWAPGPLRTPTLLV 3363 Query: 2351 IAMDETAACERVRAERINRWRVATAEASYSVVEVPGDHFDMITTSSDATTTALHGWISGL 2410 A D + AE W A E S+ V VPG HF ++ S T A+ W+S Sbjct: 3364 RAADPFSTELLGLAEEFGDW-TAAWEPSHDAVTVPGTHFTILEERSADTAGAVEDWLSTT 3422 Query: 2411 IR 2412 R Sbjct: 3423 AR 3424 Score = 724 bits (1868), Expect = 0.0 Identities = 426/898 (47%), Positives = 531/898 (59%), Gaps = 23/898 (2%) Query: 1096 LHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDR 1155 L Q R AAA EPIAIV M CR PGG++SP +LW LV+SGGD + FP DR Sbjct: 22 LRQQQRRLAAAAT-------EPIAIVAMSCRLPGGITSPEELWDLVSSGGDAMSGFPTDR 74 Query: 1156 GWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWE 1215 GWD++ LFD DPD G +Y R GGFV ++ FD FFGISP EA+AMDPQQRLLLE +WE Sbjct: 75 GWDLDNLFDADPDTPGTSYVREGGFVHGLSGFDAAFFGISPREAVAMDPQQRLLLEGAWE 134 Query: 1216 ALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQA----QWYADTGHITSVASGRISYCL 1271 A E AG+ P+ LRGS TGVFVG G Y S A + Y T SVASGR+SY Sbjct: 135 AFEHAGLRPETLRGSKTGVFVGAGGADYASLLSGAGEDVEGYVVTSSAGSVASGRLSYTF 194 Query: 1272 GLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLAT 1331 GL GPAI+VDTACSSSLVALHLAA SLR ECDLAL GG V+ATP F+ FSRQRG+A Sbjct: 195 GLEGPAITVDTACSSSLVALHLAAQSLRQRECDLALVGGVAVMATPGGFVEFSRQRGMAA 254 Query: 1332 DGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPS 1391 DGRCKAFADAADGTG+ EG G+L+++RLSDARR G VLA++ GSAVNQDGASNGLTAP+ Sbjct: 255 DGRCKAFADAADGTGWGEGVGVLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPN 314 Query: 1392 GPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLG 1451 GP+Q+RVI AL+DA + ADVD VEAHGTGT LGDPIEA+ALLATYGR + D PLWLG Sbjct: 315 GPSQERVIRQALADARLEAADVDAVEAHGTGTVLGDPIEAEALLATYGRGRSADRPLWLG 374 Query: 1452 SIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWP 1511 S+KSN+GH+QAAAGVAGVIK V A+RHQLLP TLH+D P+ VDWS G V+LLTE R WP Sbjct: 375 SLKSNIGHAQAAAGVAGVIKTVLALRHQLLPRTLHVDAPTRKVDWSAGQVELLTEERSWP 434 Query: 1512 AVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXGPGV-LAWVVSARTAAGVGAQ 1570 R RRAGVSSFGVSGTNAH + L +++SA+T A + Q Sbjct: 435 RTGQRVRRAGVSSFGVSGTNAHVILEEAPDAEQPREAVTPARLPLPFILSAKTPAALRDQ 494 Query: 1571 AGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVG-AGRDELLA-GLAEVVEGRPGV 1628 A RL +F+ DVG++L T R+ F HRAV++G AG D A E PG+ Sbjct: 495 AARLGDFLTTHPGTSLTDVGFTLATGRTAFGHRAVLLGIAGEDTHRALSALRADEDLPGI 554 Query: 1629 GVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREV 1688 SG + V+VFPGQG+QW+GM EL P L + L EV Sbjct: 555 VTGSGATATPPRGVWVFPGQGSQWVGMAVELAGSLPAFGDELRACGEALRPFVDWELSEV 614 Query: 1689 VWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXX 1748 + D L + QP L+AV V+L S+G+ P V+GHS GE++AA V+G Sbjct: 615 L--GDVGALERVDVVQPVLWAVMVSLAAAWRSFGVTPAAVVGHSQGEIAAATVAGVLSRD 672 Query: 1749 XXXXXXXMRGRLMQA-LPGGGVMYAVQAGEQELRPLLGEQ--VSVAAVNGPGSVVLSGAR 1805 +R R + A L G G M +V E+R L+ ++ + +AAVNGP V+SG Sbjct: 673 DGARVVALRARAIAAGLAGRGGMASVALPADEVRALITDRAGLEIAAVNGPAQTVVSG-- 730 Query: 1806 EAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTG 1865 + V+ +V A+G + + V +A H +E + + + +V + S V G Sbjct: 731 DDVAGLVAECEARGVWAKVIPVDYASHCAHVEEIEAELADLLADVRPQPAQTAMFSTVDG 790 Query: 1866 QLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV 1925 V YW R++R V F +V G + F E+ L S + +++ V Sbjct: 791 GWVEGPELDGGYWYRNLRRPVGFHTAVMALAGEGFSAFTEISAHPVLVSALSDAVPDGIV 850 Query: 1926 VAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 +LR+D DW LPTYAF HE +WL Sbjct: 851 SG--SLRRDDGGLDRFYAALAEVYVAGVPVDWTPAFGPDARPVADLPTYAFQHESYWL 906 Score = 714 bits (1844), Expect = 0.0 Identities = 453/1144 (39%), Positives = 615/1144 (53%), Gaps = 46/1144 (4%) Query: 4 GLHSADA---LQEWFTHYIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGI 59 GL +ADA L + ++AA G SA+ V ++ G S+ + + L+ G+ Sbjct: 2006 GLAAADAERSLLDLVRTHVAAVLGHASADDVEALRTFKEAGFDSLTAVELRNRLTTATGL 2065 Query: 60 CVPDLAVWDNPSAHDVIKSVLGGDGSQRSADSDTG--CAVLGNGPTNEPIAVIGMACRFS 117 +P V+D+P+ + ++ QR T V +++P+ ++ +CRF Sbjct: 2066 RLPATLVFDHPTPQALADHLVARLLEQRGETVTTQPPAPVAAAPSSDDPVVIVAASCRFP 2125 Query: 118 GQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEGFD 172 G V LWD +A+ + I+++PA R A + D T G FL +V FD Sbjct: 2126 GGVGSPEDLWDLVADGRHGISDFPADRGWDIDALYDADPGRRGRTYTRSGGFLGEVAEFD 2185 Query: 173 NKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLF 232 F I P EA MDPQQRLLLETSW A E AGI P +L+ S TGVFVG S DYV L Sbjct: 2186 PSLFGISPREALAMDPQQRLLLETSWEAFERAGIDPGSLRGSGTGVFVGASGADYVSLGA 2245 Query: 233 PGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECD 292 + + G + S+ + RLSY + GP++ +DTACSS+LVA HLA +SL GECD Sbjct: 2246 GAPEEVEGYLGIGSAGSVASGRLSYTFGLEGPAVTVDTACSSALVALHLAAQSLRQGECD 2305 Query: 293 LAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARR 352 LA+ AG V+ +P ++ F +SP G C+AF ADG EG G ++LERLSDARR Sbjct: 2306 LALAAGVTVMATPSLFVEFSRQRGLSPDGQCKAFADAADGAGFAEGAGTLLLERLSDARR 2365 Query: 353 AGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTS 412 G VLAV+ GSAVNQDG SNG+ APN +Q V+ A A + P ++D VEAHGTGT Sbjct: 2366 NGHRVLAVVRGSAVNQDGASNGLTAPNGPSQERVIRQALANARLTPGDVDVVEAHGTGTR 2425 Query: 413 VGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPS 472 +GD IEA AL +G+ R +PL +GS+K NIGH + AAG AG+IK V+ LQ L + Sbjct: 2426 LGDPIEAQALLATYGQDRAGGEPLWLGSVKSNIGHTQAAAGAAGVIKMVMALQHEALPRT 2485 Query: 473 GAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH-----XXXXXX 527 + P ++ ++ + ++ E ++WP R RR GVSSFG GTNAH Sbjct: 2486 LHVDAPTSHVDWSAGAVELLTEGRDWPRTEHRVRRVGVSSFGISGTNAHVVLEEAPVLRS 2545 Query: 528 XXXXXXXXXXXGPGVLA-WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRS 586 GV A W++SA T V AQA RL + + A +L A DVGY+L R+ Sbjct: 2546 VASEAPEAKGEETGVPAPWILSAATEEAVRAQARRLHDHLAARPDLTARDVGYALARHRA 2605 Query: 587 LFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPG---GKTVFVFPGQGAQWLGM 643 EH AVVVG GR++LLA A++ G A+ + PG G T F+F GQG+Q GM Sbjct: 2606 RLEHTAVVVGHGREQLLAACADLASGT--YTAAATLVRPGQPQGGTAFLFTGQGSQRPGM 2663 Query: 644 GRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG------ADAELLNTTEFAQPALFA 697 G EL A +P LD HL RPLR++++ A A LL+ TE+ QPALFA Sbjct: 2664 GGELHAAFPVFADALDETCAHLDPHLDRPLRDLMFAGPGSDEAAAALLDRTEYTQPALFA 2723 Query: 698 VEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGV 757 EVALYR +WG+RP ++GHSVGEL+AAHV+G RGRLM ALP GG Sbjct: 2724 FEVALYRQFTAWGVRPDFLIGHSVGELAAAHVAGVLPLADAAALIAARGRLMGALPPGGA 2783 Query: 758 MYAVQAGEQELRPLL------GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 M +V+AGE E+ L+ G+++ +AAVNGP + V+SG +AV + + +G + Sbjct: 2784 MLSVRAGETEVAELVAQEDESGQRLGIAAVNGPAATVVSGDEDAVLRLAETARGRGWKTA 2843 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAE-DYGSADYWVRHI 870 RL VSHAFHS M+ +L+ FR VA + P IPV+SN+TG+ V + YWVRH Sbjct: 2844 RLRVSHAFHSPHMDAVLDDFRQVASGLSYAEPTIPVVSNLTGEPVGRGEMSGPGYWVRHA 2903 Query: 871 REAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV-----VAVPTLRKDRPE 925 REAVRF D V H AG RFVE+GP L+++ +ES+ + +P R+ R E Sbjct: 2904 REAVRFHDGVRRLHRAGVRRFVEIGPDAVLSTMAQESVGGEAPRRDRRAFLPVQRRTRGE 2963 Query: 926 PFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL----ADRFXXXXXX 981 DWA+VL + LPTYAF +R+WL A Sbjct: 2964 AASLVSAVAQVHAWHGSVDWAAVLP--AARAAELPTYAFQRQRYWLDPAPAGAVPGHALG 3021 Query: 982 XXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAA 1041 RL GL AE+ AAVLA+V + A +LG A Sbjct: 3022 PIAGAAARTAVAGVDGPPGASHAPDRGARLLGLPAAERPAAVLALVRDSAAGILGHPSAD 3081 Query: 1042 QLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNR 1101 +D + + G SL+AVELR+ L + TG L T FD+PT +A+HLL+ L Sbjct: 3082 AVDPDRELLELGFDSLTAVELRDHLASATGTDLPTTLLFDHPTCADIAEHLLTRLSADGA 3141 Query: 1102 SAPA 1105 + PA Sbjct: 3142 TGPA 3145 Score = 505 bits (1300), Expect = e-140 Identities = 334/880 (37%), Positives = 456/880 (51%), Gaps = 21/880 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARR------LGAAAADWLGDEQE 158 EPIA++ M+CR G + LWD ++ A++ +P R L A D G Sbjct: 35 EPIAIVAMSCRLPGGITSPEELWDLVSSGGDAMSGFPTDRGWDLDNLFDADPDTPGTSYV 94 Query: 159 TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGV 218 G F+ + GFD FF I P EA MDPQQRLLLE +W A EHAG+ P+TL+ S TGV Sbjct: 95 R-EGGFVHGLSGFDAAFFGISPREAVAMDPQQRLLLEGAWEAFEHAGLRPETLRGSKTGV 153 Query: 219 FVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVA 278 FVG DY LL G + T + S+ + RLSY + GP++ +DTACSSSLVA Sbjct: 154 FVGAGGADYASLLSGAGEDVEGYVVTSSAGSVASGRLSYTFGLEGPAITVDTACSSSLVA 213 Query: 279 AHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEG 338 HLA +SL ECDLA+V G V+ +P + F ++ G C+AF ADG GEG Sbjct: 214 LHLAAQSLRQRECDLALVGGVAVMATPGGFVEFSRQRGMAADGRCKAFADAADGTGWGEG 273 Query: 339 CGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDP 398 GV+++ERLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ A A ++ Sbjct: 274 VGVLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQERVIRQALADARLEA 333 Query: 399 AEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLI 458 A++D VEAHGTGT +GD IEA AL +GRGR A +PL +GS+K NIGH + AAG+AG+I Sbjct: 334 ADVDAVEAHGTGTVLGDPIEAEALLATYGRGRSADRPLWLGSLKSNIGHAQAAAGVAGVI 393 Query: 459 KTVLMLQRGQLLPSGA-FEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGG 517 KTVL L R QLLP + P + ++ + ++ E + WP R RRAGVSSFG G Sbjct: 394 KTVLAL-RHQLLPRTLHVDAPTRKVDWSAGQVELLTEERSWPRTGQRVRRAGVSSFGVSG 452 Query: 518 TNAHXXXXXXXXXXXXXXXXXGPGV-LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 576 TNAH + L +++SA+T A + QA RL +F+ D Sbjct: 453 TNAHVILEEAPDAEQPREAVTPARLPLPFILSAKTPAALRDQAARLGDFLTTHPGTSLTD 512 Query: 577 VGYSLVTTRSLFEHRAVVVG-AGRDELLA-GLAEVVEGRPGVGVASGVAMPGGKTVFVFP 634 VG++L T R+ F HRAV++G AG D A E PG+ SG + V+VFP Sbjct: 513 VGFTLATGRTAFGHRAVLLGIAGEDTHRALSALRADEDLPGIVTGSGATATPPRGVWVFP 572 Query: 635 GQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPA 694 GQG+QW+GM EL P L + L EV+ D L + QP Sbjct: 573 GQGSQWVGMAVELAGSLPAFGDELRACGEALRPFVDWELSEVL--GDVGALERVDVVQPV 630 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA-LP 753 L+AV V+L S+G+ P V+GHS GE++AA V+G +R R + A L Sbjct: 631 LWAVMVSLAAAWRSFGVTPAAVVGHSQGEIAAATVAGVLSRDDGARVVALRARAIAAGLA 690 Query: 754 GGGVMYAVQAGEQELRPLLGEQ--VSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 G G M +V E+R L+ ++ + +AAVNGP V+SG + V+ +V A+G + Sbjct: 691 GRGGMASVALPADEVRALITDRAGLEIAAVNGPAQTVVSG--DDVAGLVAECEARGVWAK 748 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 + V +A H +E + + + +V + S V G V YW R++R Sbjct: 749 VIPVDYASHCAHVEEIEAELADLLADVRPQPAQTAMFSTVDGGWVEGPELDGGYWYRNLR 808 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXX 931 V F +V G + F E+ L S + +++ V +LR+D Sbjct: 809 RPVGFHTAVMALAGEGFSAFTEISAHPVLVSALSDAVPDGIVSG--SLRRDDGGLDRFYA 866 Query: 932 XXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 DW LPTYAF HE +WL Sbjct: 867 ALAEVYVAGVPVDWTPAFGPDARPVADLPTYAFQHESYWL 906 >tr|B2HJA3|B2HJA3_MYCMM Tax_Id=216594 SubName: Full=Polyketide synthase PKS;[Mycobacterium marinum] Length = 2444 Score = 1093 bits (2828), Expect = 0.0 Identities = 571/960 (59%), Positives = 673/960 (70%), Gaps = 8/960 (0%) Query: 1027 VCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPT 1086 V A +LG A ++D AF++ G S VELRNRL +TG+ L T +DY + + Sbjct: 550 VSAEVAQILGDPAAERIDRDVAFAELGFDSRMTVELRNRLAAVTGLRLPETVGWDYGSIS 609 Query: 1087 QLADHLLSHLHHQN-RSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGG 1145 +LA HL + L R P +V P+AIVG+GCRYPGGV S LW +V G Sbjct: 610 RLAAHLETELAGSGGRGKPGPSVAGGA----PVAIVGVGCRYPGGVESAGGLWDVVVGGR 665 Query: 1146 DVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQ 1205 DVI FP DRGWD+E +FDPDPDALGKTY R GGF+ FD GFFGI P EALAMDPQ Sbjct: 666 DVISGFPVDRGWDVEGVFDPDPDALGKTYCRLGGFLDGADRFDAGFFGIGPSEALAMDPQ 725 Query: 1206 QRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLG--TSQAQWYADTGHITSVA 1263 QRLLLE SWEALEDAGIDP +LRGS TGVF G+ YG G + + Y T SVA Sbjct: 726 QRLLLECSWEALEDAGIDPVSLRGSVTGVFTGLMSSDYGAGRVSGDLEGYGLTSAAASVA 785 Query: 1264 SGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGF 1323 SGR++Y LGL GPA+SVDTACSSSLVALHLAA+SLR+GECD+ALAGG TV+ATP+ F+GF Sbjct: 786 SGRVAYLLGLEGPAVSVDTACSSSLVALHLAASSLRSGECDVALAGGVTVMATPATFVGF 845 Query: 1324 SRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGA 1383 SRQRGLA DGRCKAFA AADGTGFSEGAG++VL RLS+ARR G VL ++AGSAVNQDGA Sbjct: 846 SRQRGLAADGRCKAFAGAADGTGFSEGAGVVVLMRLSEARRRGLAVLGVIAGSAVNQDGA 905 Query: 1384 SNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHT 1443 SNGLTAP+GPAQQRVI AAL++AG+T ADVDVVE HGTGT LGDPIEAQALLATYG+ Sbjct: 906 SNGLTAPNGPAQQRVIEAALANAGLTAADVDVVEGHGTGTTLGDPIEAQALLATYGQARP 965 Query: 1444 PDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQL 1503 D PLWLGSIKSNMGH+QAAAG+AGVIKMV+AMRH+L+PATLH+D PS HVDWS G V L Sbjct: 966 ADQPLWLGSIKSNMGHTQAAAGIAGVIKMVQAMRHELMPATLHVDVPSPHVDWSSGAVSL 1025 Query: 1504 LTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVVSART 1563 LT+ R WPAV GRPRRAGVSSFG+SGTNAH P L WVVS ++ Sbjct: 1026 LTQPRPWPAVDGRPRRAGVSSFGISGTNAHVIVEQVCPEVVAEAVDVSPDSLPWVVSGKS 1085 Query: 1564 AAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVE 1623 A V AQA RLL V+A LD DVG+SL R+ FE+RAVV+G R +L++GL E+ Sbjct: 1086 EAAVAAQAKRLLAAVQADEGLDRLDVGFSL-ARRTAFEYRAVVLGEDRQQLISGLTELAA 1144 Query: 1624 GRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLAR 1683 G+PG V +G A KTV VFPGQG+Q LGMG++L +P +LDR+L Sbjct: 1145 GQPGPTVLNGRAATVSKTVMVFPGQGSQRLGMGQQLHGQFPVFAQAFDAVVEQLDRYLRL 1204 Query: 1684 PLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSG 1743 PLR+ +WG D LL +TEFAQP+LFAVEVAL+ LL WG+ P +VMGHSVGELSAAHV+G Sbjct: 1205 PLRDALWGGDEHLLESTEFAQPSLFAVEVALFALLRDWGVSPDVVMGHSVGELSAAHVAG 1264 Query: 1744 XXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSG 1803 RGRLMQALP GG M+A+ A E E+ PLLGE V +AA+N P +VV+SG Sbjct: 1265 VLTLDDAAKLVAARGRLMQALPEGGAMFAIAASEHEVSPLLGEAVGIAAINAPDAVVISG 1324 Query: 1804 AREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNV 1863 R AV V+ + L +GRRV RLAVSHAFHS LMEPML F A ++ A P I ++SN+ Sbjct: 1325 ERAAVGVLAEELIDRGRRVHRLAVSHAFHSPLMEPMLADFALAAGDITAHPPRIALVSNL 1384 Query: 1864 TGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQV 1923 TG+L DYGSA YWV H+R VRFADSV GA+ F+EVGP GGL+S I +SL Sbjct: 1385 TGELAGPDYGSAQYWVEHVRRPVRFADSVRNLEELGASHFIEVGPGGGLSSAIAQSLRSP 1444 Query: 1924 SVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 V VP L KDRPE DW++V AG GG++VGLPTYAFA RFWL Sbjct: 1445 EAVTVPVLGKDRPEVNSLISAVGQLFSTGVGVDWSAVFAGSGGRQVGLPTYAFARRRFWL 1504 Score = 792 bits (2046), Expect = 0.0 Identities = 448/964 (46%), Positives = 589/964 (61%), Gaps = 24/964 (2%) Query: 19 IAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV-- 75 +A G +AE ++ D+ +LG S + + L+ V G+ +P+ WD S + Sbjct: 554 VAQILGDPAAERIDRDVAFAELGFDSRMTVELRNRLAAVTGLRLPETVGWDYGSISRLAA 613 Query: 76 -IKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKK 134 +++ L G G + G +V G P +A++G+ CR+ G V G LWD + + Sbjct: 614 HLETELAGSGGR----GKPGPSVAGGAP----VAIVGVGCRYPGGVESAGGLWDVVVGGR 665 Query: 135 SAITEYPARR------LGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDP 188 I+ +P R + D LG + G FL+ + FD FF I P EA MDP Sbjct: 666 DVISGFPVDRGWDVEGVFDPDPDALGKTYCRLGG-FLDGADRFDAGFFGIGPSEALAMDP 724 Query: 189 QQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSS 248 QQRLLLE SW ALE AGI P +L+ S TGVF G+ S+DY G + + T ++ Sbjct: 725 QQRLLLECSWEALEDAGIDPVSLRGSVTGVFTGLMSSDYGAGRVSGDLEG--YGLTSAAA 782 Query: 249 SIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVW 308 S+ + R++Y L + GP++ +DTACSSSLVA HLA SL SGECD+A+ G V+ +P + Sbjct: 783 SVASGRVAYLLGLEGPAVSVDTACSSSLVALHLAASSLRSGECDVALAGGVTVMATPATF 842 Query: 309 RGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQ 368 GF ++ G C+AF ADG EG GVVVL RLS+ARR G VL V+ GSAVNQ Sbjct: 843 VGFSRQRGLAADGRCKAFAGAADGTGFSEGAGVVVLMRLSEARRRGLAVLGVIAGSAVNQ 902 Query: 369 DGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGR 428 DG SNG+ APN AQ V+++A A + A++D VE HGTGT++GD IEA AL +G+ Sbjct: 903 DGASNGLTAPNGPAQQRVIEAALANAGLTAADVDVVEGHGTGTTLGDPIEAQALLATYGQ 962 Query: 429 GRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAF-EVPNPNIPFAEL 487 R A +PL +GSIK N+GH + AAGIAG+IK V + R +L+P+ +VP+P++ ++ Sbjct: 963 ARPADQPLWLGSIKSNMGHTQAAAGIAGVIKMVQAM-RHELMPATLHVDVPSPHVDWSSG 1021 Query: 488 GLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGVLAWVV 547 ++++ + + WPAV GRPRRAGVSSFG GTNAH P L WVV Sbjct: 1022 AVSLLTQPRPWPAVDGRPRRAGVSSFGISGTNAHVIVEQVCPEVVAEAVDVSPDSLPWVV 1081 Query: 548 SARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLA 607 S ++ A V AQA RLL V+A LD DVG+SL R+ FE+RAVV+G R +L++GL Sbjct: 1082 SGKSEAAVAAQAKRLLAAVQADEGLDRLDVGFSLAR-RTAFEYRAVVLGEDRQQLISGLT 1140 Query: 608 EVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDR 667 E+ G+PG V +G A KTV VFPGQG+Q LGMG++L +P +LDR Sbjct: 1141 ELAAGQPGPTVLNGRAATVSKTVMVFPGQGSQRLGMGQQLHGQFPVFAQAFDAVVEQLDR 1200 Query: 668 HLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAA 727 +L PLR+ +WG D LL +TEFAQP+LFAVEVAL+ LL WG+ P +VMGHSVGELSAA Sbjct: 1201 YLRLPLRDALWGGDEHLLESTEFAQPSLFAVEVALFALLRDWGVSPDVVMGHSVGELSAA 1260 Query: 728 HVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSV 787 HV+G RGRLMQALP GG M+A+ A E E+ PLLGE V +AA+N P +V Sbjct: 1261 HVAGVLTLDDAAKLVAARGRLMQALPEGGAMFAIAASEHEVSPLLGEAVGIAAINAPDAV 1320 Query: 788 VLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPV 847 V+SG R AV V+ + L +GRRV RLAVSHAFHS LMEPML F A ++ A P I + Sbjct: 1321 VISGERAAVGVLAEELIDRGRRVHRLAVSHAFHSPLMEPMLADFALAAGDITAHPPRIAL 1380 Query: 848 ISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEES 907 +SN+TG+L DYGSA YWV H+R VRFADSV GA+ F+EVGP GGL+S I +S Sbjct: 1381 VSNLTGELAGPDYGSAQYWVEHVRRPVRFADSVRNLEELGASHFIEVGPGGGLSSAIAQS 1440 Query: 908 LAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHE 967 L V VP L KDRPE DW++V AG GG++VGLPTYAFA Sbjct: 1441 LRSPEAVTVPVLGKDRPEVNSLISAVGQLFSTGVGVDWSAVFAGSGGRQVGLPTYAFARR 1500 Query: 968 RFWL 971 RFWL Sbjct: 1501 RFWL 1504 Score = 85.9 bits (211), Expect = 7e-14 Identities = 53/138 (38%), Positives = 70/138 (50%), Gaps = 4/138 (2%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RLQ LS +Q ++ V A VLGR +D F D GL SL+AVELRNRLK Sbjct: 2280 RLQALSPHQQHQLLVETVRNQAAVVLGRPSGQDIDPECTFQDLGLDSLTAVELRNRLKAA 2339 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 +G++LS T FDYPTP LA HL L TG+ ++++ + QT A D D Sbjct: 2340 SGLSLSPTLIFDYPTPATLARHLAQQLIGTGTTGSA----QIESQLETLQQTLLAIEDGD 2395 Query: 2142 GWQIVALAANGRERMTTP 2159 ++ A R+ P Sbjct: 2396 KQRVAAQLRKFLTRLLAP 2413 Score = 79.7 bits (195), Expect = 5e-12 Identities = 43/87 (49%), Positives = 51/87 (58%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RLQ LS +Q ++ V A VLGR +D F D GL SL+AVELRNRLK Sbjct: 2280 RLQALSPHQQHQLLVETVRNQAAVVLGRPSGQDIDPECTFQDLGLDSLTAVELRNRLKAA 2339 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL 1096 +G++LS T FDYPTP LA HL L Sbjct: 2340 SGLSLSPTLIFDYPTPATLARHLAQQL 2366 Score = 52.4 bits (124), Expect = 8e-04 Identities = 28/70 (40%), Positives = 40/70 (57%) Query: 2039 VCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPT 2098 V A +LG A ++D AF++ G S VELRNRL +TG+ L T +DY + + Sbjct: 550 VSAEVAQILGDPAAERIDRDVAFAELGFDSRMTVELRNRLAAVTGLRLPETVGWDYGSIS 609 Query: 2099 QLADHLLSHL 2108 +LA HL + L Sbjct: 610 RLAAHLETEL 619 >tr|B2HFX0|B2HFX0_MYCMM Tax_Id=216594 SubName: Full=Polyketide synthase and peptide synthetase;[Mycobacterium marinum] Length = 2831 Score = 1068 bits (2762), Expect = 0.0 Identities = 577/992 (58%), Positives = 672/992 (67%), Gaps = 38/992 (3%) Query: 1023 VLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDY 1082 +L++VC A VLG GAA +D ++ D GL S+ EL +RL + G + F++ Sbjct: 602 LLSVVCGQAAEVLGI-GAASVDIDRSLGDQGLNSIGVTELASRLTQVLGQDVQPVDIFNH 660 Query: 1083 PTPTQLADHL-----LSHL--------HHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 PT L L H HH A A A+ +P+AIVG+GCR+PG Sbjct: 661 PTVGDLVQILSPGEKTRHQRGVRERLGHHAASGAGAVALPA-----DPVAIVGIGCRFPG 715 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV S LW +V S DVI +FP DRGWD RLFDPDPDALGKTY GGF+ D A FD Sbjct: 716 GVDSADSLWDMVVSARDVISDFPGDRGWDAGRLFDPDPDALGKTYCAVGGFLEDAAGFDA 775 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ 1249 GFFGI+P EALAMDPQQR+LLE SWEALEDAGIDP+ALRGS+TGVFVG + YG G S Sbjct: 776 GFFGIAPREALAMDPQQRVLLEVSWEALEDAGIDPKALRGSATGVFVGTWAQPYGDGGSD 835 Query: 1250 -AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALA 1308 A YA TG TSVASGR++Y LGL GPA+SVDTACSSSLVA+H A SLR GECDLALA Sbjct: 836 SADGYAMTGTATSVASGRVAYVLGLEGPAVSVDTACSSSLVAVHQAVQSLRLGECDLALA 895 Query: 1309 GGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQP 1368 GG TV+ATPS+F+GFSRQRGLA DGRCKAFA+AADG G+ EGAG+LVLQRLSDARR G+ Sbjct: 896 GGVTVMATPSVFVGFSRQRGLAPDGRCKAFAEAADGVGWGEGAGVLVLQRLSDARRQGRV 955 Query: 1369 VLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDP 1428 VL ++ GSAVNQDGAS+GLTAP+GPAQQRVI AAL+ AG+ ADVDVVEAHGTGTRLGDP Sbjct: 956 VLGVVRGSAVNQDGASHGLTAPNGPAQQRVIRAALAGAGLGPADVDVVEAHGTGTRLGDP 1015 Query: 1429 IEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHID 1488 IEAQALLA YG+D P PLW+GSIKSNMGH+QAAAGVAGVIKMV+AMRH LLP TLH+D Sbjct: 1016 IEAQALLAVYGQDREPGRPLWVGSIKSNMGHAQAAAGVAGVIKMVQAMRHGLLPETLHVD 1075 Query: 1489 QPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXX 1548 +PS VDWS G V++L+ AR W V GRPRRAGVSSFG+SGTNAH Sbjct: 1076 EPSGQVDWSAGAVEVLSRARSWLGVPGRPRRAGVSSFGISGTNAHVIVEQALPEVAESGG 1135 Query: 1549 XXG--------------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLV 1594 G V+ WV+SA++ + AQA RLL V LD DVG SL Sbjct: 1136 VSGVCGQGVGSVESVVRASVVPWVLSAQSRQALVAQASRLLGRVGGDDGLDPVDVGLSL- 1194 Query: 1595 TTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLG 1654 R +FEHRAVVVG R+ LLAGL + G PG GV G A GKTV VFPGQGAQW G Sbjct: 1195 AQRCVFEHRAVVVGRDREALLAGLTGLARGGPGAGVVVGQAAAVGKTVLVFPGQGAQWTG 1254 Query: 1655 MGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVAL 1714 MGR L +P ELD+HL PLREV+WG D LL++TEFAQPALFA+EV L Sbjct: 1255 MGRGLHGQFPAFARAFDAAVDELDQHLPMPLREVMWGTDKGLLDSTEFAQPALFALEVGL 1314 Query: 1715 YRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQ 1774 + LLE WG+RP V+GHSVGELSAAHV+G RGRLMQ LP GGVM A+ Sbjct: 1315 WALLEHWGIRPDFVLGHSVGELSAAHVAGVLSLADAAMLVAARGRLMQGLPAGGVMVALG 1374 Query: 1775 AGEQELRPLLGEQ---VSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAF 1831 GEQE+ PLL E VS+AA+N P VV+SGA+ AV + D+LAA+G RV++LAVSHAF Sbjct: 1375 VGEQEVDPLLAESAHPVSIAAINAPEQVVISGAQAAVMTIADQLAARGHRVQQLAVSHAF 1434 Query: 1832 HSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADS 1891 HS LMEP++E+F +A V P I VISN+TG+L YGS YW HIR VRF+DS Sbjct: 1435 HSPLMEPIVEEFAEIAGRVTVEAPRIGVISNLTGELAGPGYGSKAYWREHIRRPVRFSDS 1494 Query: 1892 VCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXX 1951 V A + GAT FVE GP GLT+ IE+SL V+ V L K RPEP Sbjct: 1495 VACARAQGATHFVEAGPGAGLTAAIEQSLGSVAATVVAVLGKQRPEPDSLLDAAAQLFAS 1554 Query: 1952 XXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DW +V G GG+RV LPTYAF +RFWL Sbjct: 1555 GARLDWPAVFLGWGGRRVSLPTYAFMRQRFWL 1586 Score = 802 bits (2072), Expect = 0.0 Identities = 461/977 (47%), Positives = 586/977 (59%), Gaps = 34/977 (3%) Query: 24 GCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGGD 83 G +A V++D L D GL SI V + L+ VLG V + ++++P+ D+++ + G+ Sbjct: 615 GIGAASVDIDRSLGDQGLNSIGVTELASRLTQVLGQDVQPVDIFNHPTVGDLVQILSPGE 674 Query: 84 GS--QRSADSDTGC-AVLGNGPTN---EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAI 137 + QR G A G G +P+A++G+ CRF G V LWD + + I Sbjct: 675 KTRHQRGVRERLGHHAASGAGAVALPADPVAIVGIGCRFPGGVDSADSLWDMVVSARDVI 734 Query: 138 TEYP------ARRLGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQR 191 +++P A RL D LG + G FLED GFD FF I P EA MDPQQR Sbjct: 735 SDFPGDRGWDAGRLFDPDPDALGKTYCAVGG-FLEDAAGFDAGFFGIAPREALAMDPQQR 793 Query: 192 LLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSII 251 +LLE SW ALE AGI PK L+ S TGVFVG + Y G + TG ++S+ Sbjct: 794 VLLEVSWEALEDAGIDPKALRGSATGVFVGTWAQPYGD---GGSDSADGYAMTGTATSVA 850 Query: 252 ANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGF 311 + R++Y L + GP++ +DTACSSSLVA H A +SL GECDLA+ G V+ +P V+ GF Sbjct: 851 SGRVAYVLGLEGPAVSVDTACSSSLVAVHQAVQSLRLGECDLALAGGVTVMATPSVFVGF 910 Query: 312 QEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGR 371 ++P G C+AF ADG+ GEG GV+VL+RLSDARR GR VL V+ GSAVNQDG Sbjct: 911 SRQRGLAPDGRCKAFAEAADGVGWGEGAGVLVLQRLSDARRQGRVVLGVVRGSAVNQDGA 970 Query: 372 SNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQ 431 S+G+ APN AQ V+ +A A + PA++D VEAHGTGT +GD IEA AL V+G+ R+ Sbjct: 971 SHGLTAPNGPAQQRVIRAALAGAGLGPADVDVVEAHGTGTRLGDPIEAQALLAVYGQDRE 1030 Query: 432 AAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAV 491 +PL +GSIK N+GH + AAG+AG+IK V ++ G L + + P+ + ++ + V Sbjct: 1031 PGRPLWVGSIKSNMGHAQAAAGVAGVIKMVQAMRHGLLPETLHVDEPSGQVDWSAGAVEV 1090 Query: 492 VEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXG------------ 539 + + W V GRPRRAGVSSFG GTNAH G Sbjct: 1091 LSRARSWLGVPGRPRRAGVSSFGISGTNAHVIVEQALPEVAESGGVSGVCGQGVGSVESV 1150 Query: 540 --PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGA 597 V+ WV+SA++ + AQA RLL V LD DVG SL R +FEHRAVVVG Sbjct: 1151 VRASVVPWVLSAQSRQALVAQASRLLGRVGGDDGLDPVDVGLSL-AQRCVFEHRAVVVGR 1209 Query: 598 GRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXX 657 R+ LLAGL + G PG GV G A GKTV VFPGQGAQW GMGR L +P Sbjct: 1210 DREALLAGLTGLARGGPGAGVVVGQAAAVGKTVLVFPGQGAQWTGMGRGLHGQFPAFARA 1269 Query: 658 XXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVM 717 ELD+HL PLREV+WG D LL++TEFAQPALFA+EV L+ LLE WG+RP V+ Sbjct: 1270 FDAAVDELDQHLPMPLREVMWGTDKGLLDSTEFAQPALFALEVGLWALLEHWGIRPDFVL 1329 Query: 718 GHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQ-- 775 GHSVGELSAAHV+G RGRLMQ LP GGVM A+ GEQE+ PLL E Sbjct: 1330 GHSVGELSAAHVAGVLSLADAAMLVAARGRLMQGLPAGGVMVALGVGEQEVDPLLAESAH 1389 Query: 776 -VSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAV 834 VS+AA+N P VV+SGA+ AV + D+LAA+G RV++LAVSHAFHS LMEP++E+F + Sbjct: 1390 PVSIAAINAPEQVVISGAQAAVMTIADQLAARGHRVQQLAVSHAFHSPLMEPIVEEFAEI 1449 Query: 835 ADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEV 894 A V P I VISN+TG+L YGS YW HIR VRF+DSV A + GAT FVE Sbjct: 1450 AGRVTVEAPRIGVISNLTGELAGPGYGSKAYWREHIRRPVRFSDSVACARAQGATHFVEA 1509 Query: 895 GPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGG 954 GP GLT+ IE+SL V+ V L K RPEP DW +V G GG Sbjct: 1510 GPGAGLTAAIEQSLGSVAATVVAVLGKQRPEPDSLLDAAAQLFASGARLDWPAVFLGWGG 1569 Query: 955 QRVGLPTYAFAHERFWL 971 +RV LPTYAF +RFWL Sbjct: 1570 RRVSLPTYAFMRQRFWL 1586 Score = 82.0 bits (201), Expect = 1e-12 Identities = 42/80 (52%), Positives = 52/80 (65%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL +QQ ++ +VC AAVLG A L+ F + G SL+AVELRNRLKT+ Sbjct: 2665 RLYGLKPEKQQDLLVDLVCTQAAAVLGHPSATDLNPASTFQNMGFDSLTAVELRNRLKTV 2724 Query: 1070 TGVTLSATTAFDYPTPTQLA 1089 TG+ LS T FD+PTPT LA Sbjct: 2725 TGLGLSPTLVFDHPTPTALA 2744 Score = 82.0 bits (201), Expect = 1e-12 Identities = 42/80 (52%), Positives = 52/80 (65%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL +QQ ++ +VC AAVLG A L+ F + G SL+AVELRNRLKT+ Sbjct: 2665 RLYGLKPEKQQDLLVDLVCTQAAAVLGHPSATDLNPASTFQNMGFDSLTAVELRNRLKTV 2724 Query: 2082 TGVTLSATTAFDYPTPTQLA 2101 TG+ LS T FD+PTPT LA Sbjct: 2725 TGLGLSPTLVFDHPTPTALA 2744 Score = 43.5 bits (101), Expect = 0.38 Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Query: 2035 VLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDY 2094 +L++VC A VLG GAA +D ++ D GL S+ EL +RL + G + F++ Sbjct: 602 LLSVVCGQAAEVLGI-GAASVDIDRSLGDQGLNSIGVTELASRLTQVLGQDVQPVDIFNH 660 Query: 2095 PTPTQLADHL 2104 PT L L Sbjct: 661 PTVGDLVQIL 670 >tr|Q740I0|Q740I0_MYCPA Tax_Id=1770 (pks8)SubName: Full=Pks8;[Mycobacterium paratuberculosis] Length = 1095 Score = 1057 bits (2733), Expect = 0.0 Identities = 572/1027 (55%), Positives = 668/1027 (65%), Gaps = 24/1027 (2%) Query: 1095 HLHHQNR-SAPAAAVRTRV-----RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVI 1148 HL + R +A R RV R+ EP+A+VGM CRY GGV SP LW LV G D + Sbjct: 7 HLDYLKRLTADLRRTRRRVAELEGRLSEPVAVVGMACRYAGGVDSPEALWDLVIEGRDTV 66 Query: 1149 GEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRL 1208 +FP DRGWD+E L+DPDPDA GK YTR G F+ DFD GFFGI P EALAMDPQQR+ Sbjct: 67 SDFPVDRGWDVEGLYDPDPDAKGKMYTRQGSFLQHAGDFDAGFFGIGPSEALAMDPQQRI 126 Query: 1209 LLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS-QAQWYADTGHITSVASGRI 1267 +LE WEALE AGIDP ALRG++TGVF G+ GYG + + Y TG SV SGR+ Sbjct: 127 MLEICWEALERAGIDPSALRGTATGVFAGVIHAGYGGEVKGELEGYGLTGSTLSVTSGRV 186 Query: 1268 SYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQR 1327 SY LGL GPA+SVDTACSSSLVA+HLAA SLR+GECDLALAGG TV+ATP+ F+ FSRQR Sbjct: 187 SYVLGLEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTVMATPAAFVEFSRQR 246 Query: 1328 GLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGL 1387 LA DGRCK +A AADGT +SEGAG+LVL+RL DARR G PV A+L GSAVNQDGASNGL Sbjct: 247 ALAPDGRCKVYAGAADGTSWSEGAGVLVLERLGDARRLGHPVWAVLRGSAVNQDGASNGL 306 Query: 1388 TAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAP 1447 TAP+GP+QQRVI AAL++AG++ DVDVVE HGTGT LGDPIEAQALLATYG+D D P Sbjct: 307 TAPNGPSQQRVIRAALANAGLSAVDVDVVEGHGTGTVLGDPIEAQALLATYGQDRPADRP 366 Query: 1448 LWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEA 1507 LWLGSIKSN+GH+ AAAGVAGVIKMV+A+RH ++P TLH+D PS HVDWS G V LLT+ Sbjct: 367 LWLGSIKSNIGHTSAAAGVAGVIKMVQAIRHGVMPKTLHVDVPSPHVDWSAGAVSLLTDP 426 Query: 1508 REWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXG----PGVLAWVVSART 1563 R WP G PRRAGVSSFG+SGTNAH V+ WVVSAR+ Sbjct: 427 RPWPE-HGGPRRAGVSSFGISGTNAHVIVEQAPAAAETEAAPASSAMPDAVVPWVVSARS 485 Query: 1564 AAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVE 1623 A + QA RLL+ V A + DVG+SLV+TR++FEHRAVVVG R L GLA + Sbjct: 486 AEALAGQARRLLDHVTADAQASPLDVGWSLVSTRAVFEHRAVVVGCERGALATGLAGLAS 545 Query: 1624 GRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLAR 1683 GRP G A GKTV VFPGQG+Q LGMGR+L + +D H Sbjct: 546 GRPDAATVVGRARATGKTVLVFPGQGSQTLGMGRQLYERFVVFARALDEAVAVVDEHSRL 605 Query: 1684 PLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSG 1743 P+REV+WGAD ELL +TEFAQPALF EVAL L ES G+ P +VMGHSVGE++AA V+G Sbjct: 606 PVREVMWGADPELLQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAG 665 Query: 1744 XXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSG 1803 RG LM ALP GGVM AV AGE ++ PL+G VS+AAVNGP +VVLSG Sbjct: 666 VLSLPDAARLVAARGALMAALPAGGVMVAVTAGEAQVAPLVGGGVSIAAVNGPDAVVLSG 725 Query: 1804 AREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNV 1863 +EAV+ V +RLA G RV RLAVSHAFHS LMEPML F A A + P IP++SN+ Sbjct: 726 EQEAVAAVAERLAGSGARVHRLAVSHAFHSALMEPMLGGFAAAAAGIEPRPPRIPLVSNL 785 Query: 1864 TGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQV 1923 TGQL YG+ YWV H+R V+F V A AGA F+E+GP LT+ +++SL+ Sbjct: 786 TGQLAGPGYGTPQYWVEHVRAPVQFLAGVRAAEQAGAGTFLELGPGAALTAAVDQSLSTE 845 Query: 1924 SVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 A+ TL KDRPE DWA V AG +RV LPTYAFA ERFWL Sbjct: 846 GATAIATLPKDRPETESALHAAGHLFTRGHRLDWAGVFAGLPARRVELPTYAFARERFWL 905 Query: 1984 ADRFXXXXXXXXXXXLXXXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHT 2043 RL L EQQ + +VCEH Sbjct: 906 G------------GASLAGAPAGAAPVGGGTRAPELAHRLHALPRDEQQRVLRELVCEHA 953 Query: 2044 AAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADH 2103 AAVLG +D +AF+D G SL VELRNRL T TG LS T FDYPTPT LADH Sbjct: 954 AAVLGHPDGDAIDPHRAFADLGFDSLIGVELRNRLTTHTGTALSRTLIFDYPTPTALADH 1013 Query: 2104 LLSHLHH 2110 L L H Sbjct: 1014 LRRQLLH 1020 Score = 803 bits (2073), Expect = 0.0 Identities = 463/1010 (45%), Positives = 581/1010 (57%), Gaps = 31/1010 (3%) Query: 101 GPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGD----- 155 G +EP+AV+GMACR++G V LWD + E + ++++P R + D Sbjct: 30 GRLSEPVAVVGMACRYAGGVDSPEALWDLVIEGRDTVSDFPVDRGWDVEGLYDPDPDAKG 89 Query: 156 EQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSH 215 + T G FL+ FD FF I P EA MDPQQR++LE W ALE AGI P L+ + Sbjct: 90 KMYTRQGSFLQHAGDFDAGFFGIGPSEALAMDPQQRIMLEICWEALERAGIDPSALRGTA 149 Query: 216 TGVFVGVSSTDYVRLLFPGGRKPTIWDN---TGGSSSIIANRLSYFLDVNGPSLVIDTAC 272 TGVF GV Y GG + TG + S+ + R+SY L + GP++ +DTAC Sbjct: 150 TGVFAGVIHAGY------GGEVKGELEGYGLTGSTLSVTSGRVSYVLGLEGPAVSVDTAC 203 Query: 273 SSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADG 332 SSSLVA HLA +SL SGECDLA+ G V+ +P + F ++P G C+ + ADG Sbjct: 204 SSSLVAMHLAAQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALAPDGRCKVYAGAADG 263 Query: 333 MVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACK 392 EG GV+VLERL DARR G V AVL GSAVNQDG SNG+ APN +Q V+ +A Sbjct: 264 TSWSEGAGVLVLERLGDARRLGHPVWAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAALA 323 Query: 393 CADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAA 452 A + ++D VE HGTGT +GD IEA AL +G+ R A +PL +GSIK NIGH AA Sbjct: 324 NAGLSAVDVDVVEGHGTGTVLGDPIEAQALLATYGQDRPADRPLWLGSIKSNIGHTSAAA 383 Query: 453 GIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSS 512 G+AG+IK V ++ G + + +VP+P++ ++ ++++ + + WP G PRRAGVSS Sbjct: 384 GVAGVIKMVQAIRHGVMPKTLHVDVPSPHVDWSAGAVSLLTDPRPWPEH-GGPRRAGVSS 442 Query: 513 FGFGGTNAHXXXXXXXXXXXXXXXXXGPG----VLAWVVSARTAAGVGAQAGRLLEFVRA 568 FG GTNAH V+ WVVSAR+A + QA RLL+ V A Sbjct: 443 FGISGTNAHVIVEQAPAAAETEAAPASSAMPDAVVPWVVSARSAEALAGQARRLLDHVTA 502 Query: 569 GRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGK 628 + DVG+SLV+TR++FEHRAVVVG R L GLA + GRP G A GK Sbjct: 503 DAQASPLDVGWSLVSTRAVFEHRAVVVGCERGALATGLAGLASGRPDAATVVGRARATGK 562 Query: 629 TVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTT 688 TV VFPGQG+Q LGMGR+L + +D H P+REV+WGAD ELL +T Sbjct: 563 TVLVFPGQGSQTLGMGRQLYERFVVFARALDEAVAVVDEHSRLPVREVMWGADPELLQST 622 Query: 689 EFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRL 748 EFAQPALF EVAL L ES G+ P +VMGHSVGE++AA V+G RG L Sbjct: 623 EFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAGVLSLPDAARLVAARGAL 682 Query: 749 MQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGR 808 M ALP GGVM AV AGE ++ PL+G VS+AAVNGP +VVLSG +EAV+ V +RLA G Sbjct: 683 MAALPAGGVMVAVTAGEAQVAPLVGGGVSIAAVNGPDAVVLSGEQEAVAAVAERLAGSGA 742 Query: 809 RVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVR 868 RV RLAVSHAFHS LMEPML F A A + P IP++SN+TGQL YG+ YWV Sbjct: 743 RVHRLAVSHAFHSALMEPMLGGFAAAAAGIEPRPPRIPLVSNLTGQLAGPGYGTPQYWVE 802 Query: 869 HIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFX 928 H+R V+F V A AGA F+E+GP LT+ +++SL+ A+ TL KDRPE Sbjct: 803 HVRAPVQFLAGVRAAEQAGAGTFLELGPGAALTAAVDQSLSTEGATAIATLPKDRPETES 862 Query: 929 XXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADRFXXXXXXXXXXXLX 988 DWA V AG +RV LPTYAFA ERFWL Sbjct: 863 ALHAAGHLFTRGHRLDWAGVFAGLPARRVELPTYAFARERFWLG------------GASL 910 Query: 989 XXXXXXXXXXXXXXXXXXXXXRLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQA 1048 RL L EQQ + +VCEH AAVLG +D +A Sbjct: 911 AGAPAGAAPVGGGTRAPELAHRLHALPRDEQQRVLRELVCEHAAAVLGHPDGDAIDPHRA 970 Query: 1049 FSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHH 1098 F+D G SL VELRNRL T TG LS T FDYPTPT LADHL L H Sbjct: 971 FADLGFDSLIGVELRNRLTTHTGTALSRTLIFDYPTPTALADHLRRQLLH 1020 >tr|Q9X993|Q9X993_9ACTO Tax_Id=68242 (pimS1)SubName: Full=PimS1 protein; SubName: Full=Polyketide synthase;[Streptomyces natalensis] Length = 6797 Score = 1056 bits (2730), Expect = 0.0 Identities = 559/981 (56%), Positives = 662/981 (67%), Gaps = 11/981 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL G E++ +L +V A VLG +++ + F D G SL+AVELRNRL Sbjct: 3191 RLSGRGTVERREVLLDLVRAQIAVVLGHANPETIESTRVFQDLGFDSLTAVELRNRLNNA 3250 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSA--PAAAVRTRVRIDEPIAIVGMGCRY 1127 TG+ LSAT FDYPT L D LL L A PA D+P+ IVGM CRY Sbjct: 3251 TGLRLSATAVFDYPTADALVDFLLDELFGAQEEAELPAPVPSPAGAADDPVVIVGMSCRY 3310 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGGV SP LW+LV+ G D + +FP DRGWD+E L+ PDP+ALG +YTR GGF+ + A+F Sbjct: 3311 PGGVGSPEDLWRLVSEGVDAVSDFPTDRGWDVESLYSPDPEALGTSYTRSGGFLHEAAEF 3370 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--L 1245 DP FFG+SP EALA D QQRLLLET+WEA+E GIDP +LRGS TGVF G+ YG L Sbjct: 3371 DPDFFGMSPREALATDAQQRLLLETTWEAIERTGIDPASLRGSRTGVFAGVMYTDYGDLL 3430 Query: 1246 GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 Q + Y G S+ASGR+SY G GPA++VDTACSSSLVALH AA SLR+GEC L Sbjct: 3431 VGDQFEGYRSNGSAASIASGRVSYTFGFEGPAVTVDTACSSSLVALHWAAQSLRSGECSL 3490 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 A+AGG TV++TP+ F+ FSRQRGL+ DGRCKAFADAADG G+ EG GMLVL+RLSDARR Sbjct: 3491 AVAGGVTVMSTPTTFVEFSRQRGLSADGRCKAFADAADGVGWGEGVGMLVLERLSDARRN 3550 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G VLA++ GSAVNQDGASNGLTAP+GPAQQRVI AL+ AG++ ADVD VEAHGTGT L Sbjct: 3551 GHRVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALASAGLSAADVDAVEAHGTGTTL 3610 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIEAQALLATYG++ D PL LGS+KSN+GH+QAA+GVAGVIKMV AMRH +LP TL Sbjct: 3611 GDPIEAQALLATYGQERPEDRPLLLGSVKSNIGHAQAASGVAGVIKMVLAMRHGVLPRTL 3670 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH---XXXXXXXXX 1542 H+D+PS+HVDWS G V+LLT EWP G PRRAGVSSFGVSGTNAH Sbjct: 3671 HVDEPSSHVDWSAGAVELLTSEAEWPQGEG-PRRAGVSSFGVSGTNAHVILEQPGPDAAD 3729 Query: 1543 XXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEH 1602 PG LAWV+SAR A + QA RLL V L A D+G+SLVT RS F H Sbjct: 3730 AAPDATVTDPGALAWVLSARNEAALRCQAARLLSLVAGSDALCARDIGHSLVTGRSSFAH 3789 Query: 1603 RAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAG 1662 RAVV G RD L+ L+ + G G+A G A G+T F+F GQG+Q LGMG EL A Sbjct: 3790 RAVVWGQDRDALVRALSALAVGEADAGLAEG-ASGAGRTAFLFSGQGSQRLGMGWELYAR 3848 Query: 1663 YPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWG 1722 YP LD HL RPLR+VVWG DAELLN T +AQ LFA+EVALYRL ESWG Sbjct: 3849 YPVFADAFDAVCAALDEHLERPLRDVVWGEDAELLNQTAYAQAGLFAIEVALYRLAESWG 3908 Query: 1723 MRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRP 1782 MRP V GHS+GE++AAHVSG RGRLMQ LP GG M A++A E E+ P Sbjct: 3909 MRPDFVAGHSIGEVAAAHVSGVFSLPDACALVAARGRLMQQLPSGGAMMAIRATEDEVLP 3968 Query: 1783 LLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQ 1842 L E VS+AAVNGP SVV+SGA +AV + A +GR+ RL VSHAFHS LMEPMLE+ Sbjct: 3969 HLAEGVSLAAVNGPSSVVISGAEDAVLAIAAHFAGEGRKTTRLRVSHAFHSPLMEPMLEE 4028 Query: 1843 FRAVADEVYAGRPAIPVISNVTGQLV-AEDYGSADYWVRHIREAVRFADSVCFAHSAGAT 1901 FRAV + G P IPV+SN+TG+L E ADYWVRH+REAVRFAD + + G T Sbjct: 4029 FRAVVTRLSFGTPTIPVVSNLTGRLAEPEQLAHADYWVRHVREAVRFADGIQALRAEGVT 4088 Query: 1902 RFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVL 1961 RF+E+GP G L+++ ES + +V+A P LR+DRPE DW Sbjct: 4089 RFLELGPDGVLSAMARESASDDAVLA-PVLRRDRPEETALLGALAQLYVRGAHVDWTVPF 4147 Query: 1962 AGCGGQRVGLPTYAFAHERFW 1982 AG G + LPTYAF HERFW Sbjct: 4148 AGSGARWADLPTYAFQHERFW 4168 Score = 987 bits (2551), Expect = 0.0 Identities = 544/996 (54%), Positives = 653/996 (65%), Gaps = 28/996 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GLS AE++ A+L +V A VLG G + +AF D GL SL+A+ELRN L Sbjct: 4892 RLAGLSTAERREALLDVVRAQIATVLGHAGPETIAPDRAFQDLGLDSLTAIELRNLLGKA 4951 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSA----PAAAVRTRVRIDEPIAIVGMGC 1125 TG+ L ATT FDYPT LA HLL L P D+P+ IVGM C Sbjct: 4952 TGLRLPATTVFDYPTVDALAAHLLDELFGAETGTATETPLPVPGLPSLADDPVVIVGMSC 5011 Query: 1126 RYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVA 1185 R+PGGV+SP LW+LVA G D + FP DRGW+I+ +DP+ + G TR GGF+ D A Sbjct: 5012 RFPGGVASPEDLWRLVADGVDAVSAFPTDRGWEIDDTYDPERE--GAIATRSGGFLHDAA 5069 Query: 1186 DFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG- 1244 +FDP FFG+SP EAL D QQRLLLET+WEALE AG+DP LRGS TGVF G+ Y Sbjct: 5070 EFDPEFFGMSPREALTTDAQQRLLLETTWEALERAGMDPATLRGSRTGVFAGVMYHDYST 5129 Query: 1245 -LGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGEC 1303 L + + Y +G SVASGR+SY G GPA++VDTACSSSLVALHLAA SLR+GEC Sbjct: 5130 LLSGREFEGYQGSGSAGSVASGRVSYTFGFEGPAVTVDTACSSSLVALHLAAQSLRSGEC 5189 Query: 1304 DLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDAR 1363 LALAGG TV++TP F+ FSRQ GL+ DGRCKAFADAADG G++EGAG+LVL+RLSDAR Sbjct: 5190 SLALAGGVTVMSTPLTFVEFSRQGGLSADGRCKAFADAADGVGWAEGAGILVLERLSDAR 5249 Query: 1364 RAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGT 1423 R G +LA + GSAVNQDGASNGLTAP+GPAQQRVI AL+ AG++ ADVD VEAHGTGT Sbjct: 5250 RNGHRILATVRGSAVNQDGASNGLTAPNGPAQQRVIRQALASAGLSAADVDAVEAHGTGT 5309 Query: 1424 RLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPA 1483 LGDPIEAQALLATYG++ D PL LGS+KSN+GH+QAA+GVAGVIKMV AMRH +LP Sbjct: 5310 TLGDPIEAQALLATYGQERPEDRPLLLGSVKSNIGHAQAASGVAGVIKMVLAMRHGVLPR 5369 Query: 1484 TLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH---------- 1533 TLH+D+PS+HVDWS G V+LLT EWP G PRRAGVSSFG+SGTNAH Sbjct: 5370 TLHVDEPSSHVDWSAGAVELLTSEAEWPQGEG-PRRAGVSSFGISGTNAHVILEQPEPVA 5428 Query: 1534 -----XXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 1588 G V A ++S R+A+ + AQA RLL + D Sbjct: 5429 AETESITPDTAPDAAEDEAADSGTPVPA-LLSGRSASALRAQAARLLSRLDGDPGPRITD 5487 Query: 1589 VGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGR-PGVGVASGVAMPGGKTVFVFPG 1647 V YSL T RS F HRAV++ A R +LL L+ + EG V + GK F+F G Sbjct: 5488 VAYSLATGRSAFPHRAVILAANRADLLHSLSALAEGHTEAPAVVAQDRARSGKLAFLFSG 5547 Query: 1648 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPAL 1707 QG+Q LGMGREL YP LD HL RPLR+V+WG DAELLN T +AQ L Sbjct: 5548 QGSQRLGMGRELYGRYPAFAEALDAVCAALDAHLDRPLRDVIWGEDAELLNRTGYAQTGL 5607 Query: 1708 FAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGG 1767 FA+EVAL+RLLESWG+RP ++GHS+GE++AAHV+G RGRLMQ LP G Sbjct: 5608 FAIEVALFRLLESWGVRPDHLLGHSIGEIAAAHVAGVLSLPDACALVAARGRLMQQLPSG 5667 Query: 1768 GVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 G M A++A E E+ P L E VS+AAVNGP SVV+SGA + V + +GR+ RL V Sbjct: 5668 GAMMAIRATEDEVLPHLAEGVSLAAVNGPSSVVVSGAEDEVLALAAHFEEEGRKTTRLRV 5727 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQ-LVAEDYGSADYWVRHIREAV 1886 SHAFHS LMEPML FRAVAD + P IPV+SNVTG+ AE+ A+YWV H+REAV Sbjct: 5728 SHAFHSPLMEPMLADFRAVADGMTYAAPRIPVVSNVTGRPATAEELCCAEYWVGHVREAV 5787 Query: 1887 RFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXX 1946 RFAD V G T F+E+GP G L++L ES A SV+A P LRK+RPE Sbjct: 5788 RFADGVGALREQGVTTFLELGPDGSLSALAAESAADDSVLA-PVLRKNRPEAPALLTALA 5846 Query: 1947 XXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 DW++ AG G + V LPTYAF HERFW Sbjct: 5847 RLHAQGTPVDWSAAFAGTGARWVDLPTYAFQHERFW 5882 Score = 958 bits (2476), Expect = 0.0 Identities = 526/996 (52%), Positives = 640/996 (64%), Gaps = 33/996 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 R+ L AEQ+ A L MV E A VLG +DA +AF + G SL AV+LRNRL Sbjct: 1457 RIGALPPAEQEKAFLTMVREEAARVLGHPSPDTVDAQRAFREQGFDSLMAVDLRNRLSAA 1516 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVR-TRVRIDEPIAIVGMGCRYP 1128 TG+ L AT FD+PTP A L S + + PA V+ + +DEP+AI+GM CR+P Sbjct: 1517 TGLRLPATLLFDHPTPLAAAACLRSEV--LGAAGPATVVQASTAALDEPVAIIGMACRFP 1574 Query: 1129 GGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFD 1188 GGV SP LW+L+A GGD I P DRGWD++RL+ PDPD G +Y R GGF+ ADFD Sbjct: 1575 GGVHSPEALWRLLAEGGDAITPMPADRGWDLDRLYHPDPDHQGTSYARGGGFLDGAADFD 1634 Query: 1189 PGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS 1248 FFGISP EALAMDPQQRLLLET WE LE AGIDP++LRGSSTGVF G YG Sbjct: 1635 ADFFGISPREALAMDPQQRLLLET-WEVLEQAGIDPESLRGSSTGVFAGTNTQDYGTALD 1693 Query: 1249 QAQWYAD----TGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 AQ A TG+ SV SGR+SY G GPA++VDTACSSSLVALH+AA +LR GEC Sbjct: 1694 AAQDEAGGHRLTGNAMSVVSGRVSYTFGFEGPALTVDTACSSSLVALHMAAQALRQGECS 1753 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 LA+AGG TV+ATPS F+ F+RQRGLA DGRCK FA AADGTG+SEG G+L+++RLSDARR Sbjct: 1754 LAVAGGVTVMATPSSFVEFARQRGLAPDGRCKPFAAAADGTGWSEGVGLLLVERLSDARR 1813 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 G VLA++ GSAVNQDGASNGL+APSGP+QQRVI AL++A + ++VD VEAHGTGT Sbjct: 1814 NGHQVLAVVRGSAVNQDGASNGLSAPSGPSQQRVIRQALANARVAASEVDAVEAHGTGTT 1873 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG++ PL LG++KSN+GH+QAAAGVAGV+KMV AMRH +LP T Sbjct: 1874 LGDPIEAQALLATYGQER----PLLLGAVKSNLGHTQAAAGVAGVMKMVLAMRHGMLPRT 1929 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH----------- 1533 LH+D+P+ HVDW+ G V+LLTE +WP G PRRA VS+FG+SGTNAH Sbjct: 1930 LHVDEPTGHVDWTAGAVELLTEHTDWPE-TGHPRRAAVSAFGISGTNAHVVLELPAAEQP 1988 Query: 1534 ------XXXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 1587 G ++SA++ + + AQA RL + L Sbjct: 1989 LVEQPSAAEPDAPATAPDRTPTASDGTAPLLLSAKSESALRAQAARLHSHLERDPALRLT 2048 Query: 1588 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 1647 D Y+L+T R+ F HRA V A + L L + G V +G A G V +F G Sbjct: 2049 DAAYTLMTHRTAFAHRAAVRAADHEAALRALTALAAGEADPAVDTGTAHTGRDAV-LFSG 2107 Query: 1648 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPAL 1707 QG+Q +GMGREL YP LD HL RPLR+VV G D ELLN T +AQ L Sbjct: 2108 QGSQRIGMGRELSGRYPVFAEAFDTVCAALDEHLDRPLRDVVRGEDEELLNRTVYAQAGL 2167 Query: 1708 FAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGG 1767 FA+EVAL+RL+ESWG+RP V GHSVGE++AAHV+G RGRLMQALP G Sbjct: 2168 FAIEVALFRLVESWGVRPHYVAGHSVGEIAAAHVAGVFSLADACALVAARGRLMQALPAG 2227 Query: 1768 GVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV 1827 G M A++A E E+ P L + VS+AAVNGP SVV+SGA AV + GR+ RL V Sbjct: 2228 GAMAAIRATEDEVLPHLADSVSIAAVNGPSSVVVSGAEHAVLSIAAHFEGAGRKTTRLRV 2287 Query: 1828 SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED-YGSADYWVRHIREAV 1886 SHAFHS LM+PML FRAVA+ + G P + V+SNVTGQL D + +YWV H+R AV Sbjct: 2288 SHAFHSPLMDPMLADFRAVAEGLTYGEPELAVVSNVTGQLATPDQLRTPEYWVTHVRAAV 2347 Query: 1887 RFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXX 1946 RFAD + + G TRF+E+GP G L++L ES A V P LRKDR E Sbjct: 2348 RFADGIRALGAEGVTRFLELGPDGVLSALARES-APDDAVCTPVLRKDRSEAATLLAALT 2406 Query: 1947 XXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 DW + LAG V LPTYAF H+RFW Sbjct: 2407 HLHVHGTEIDWTAFLAGRDAHAVDLPTYAFQHQRFW 2442 Score = 884 bits (2283), Expect = 0.0 Identities = 476/889 (53%), Positives = 587/889 (66%), Gaps = 17/889 (1%) Query: 1110 TRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDA 1169 T + EP+AIV M CR+PGGV SP +LW+L+ G D + FP +RGWD++ L+ DP Sbjct: 28 TEAKQREPLAIVSMACRFPGGVRSPEELWELLRDGVDAVSSFPRNRGWDLDALYHSDPAH 87 Query: 1170 LGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRG 1229 G +Y R GGF+ D +FDPGFFGISP EALAMDPQQRLLLET+WEA+E AGIDP++L G Sbjct: 88 QGTSYAREGGFLHDAGEFDPGFFGISPREALAMDPQQRLLLETAWEAVERAGIDPESLAG 147 Query: 1230 SSTGVFVGIYGDGYGLG----TSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACS 1285 S TGVFVG GY + + TG+ S+ASGRISY LGL GPA++VDTACS Sbjct: 148 SRTGVFVGTGHGGYDAEGRRRADEVGGHLLTGNHISIASGRISYVLGLEGPALTVDTACS 207 Query: 1286 SSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGT 1345 SSLVALHLA ++LR EC +AL GG+TV++TP +F+ FSRQRGLA DGRCK FA AADGT Sbjct: 208 SSLVALHLAMHALRRDECAMALVGGATVMSTPQMFVEFSRQRGLAPDGRCKPFAAAADGT 267 Query: 1346 GFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSD 1405 G+SEG G+L+++RLSDA R G PVLA+L GSAVNQDGASNGLTAP+GP+QQRVI AL+ Sbjct: 268 GWSEGVGLLLVERLSDAVRNGYPVLAVLKGSAVNQDGASNGLTAPNGPSQQRVIRQALTG 327 Query: 1406 AGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAG 1465 AG+ +D+D VEAHGTGT LGDP+EA ALLATYG+ D P LGS+KSN+GH+QAAAG Sbjct: 328 AGLAASDIDAVEAHGTGTTLGDPVEAHALLATYGQQRAADRPCGLGSMKSNIGHTQAAAG 387 Query: 1466 VAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSF 1525 +AGV+KMV AMRH LP TLH+D+P+ HVDWS G +LL E WP+ GRPRRA VSSF Sbjct: 388 IAGVMKMVLAMRHGHLPRTLHLDEPTGHVDWSEGNARLLAEPEPWPS-AGRPRRAAVSSF 446 Query: 1526 GVSGTNAHXXXXXXXXXXXXXXXXXG--PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRE 1583 G+SGTNAH PG L W++SART AG+ AQA RL +R + Sbjct: 447 GISGTNAHVILEQAPAHEAEPAPEPAARPGALPWILSARTEAGLRAQADRLGRHLRDRAD 506 Query: 1584 LDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVF 1643 L+ V ++L TR+L EHRAVVV R+E L GL + GR G+ SGVA+ + F Sbjct: 507 LEPAAVAHALADTRTLMEHRAVVVAGDREEFLRGLDALAAGRTANGLVSGVAVKAA-SAF 565 Query: 1644 VFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVW----GADAELLNT 1699 +F GQG+Q GMGREL A +P ELD HL RPLR++V+ A+A LL+ Sbjct: 566 LFAGQGSQRPGMGRELHAAHPVFATAFDAVCAELDPHLDRPLRDIVFAEEGSAEAALLDQ 625 Query: 1700 TEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGR 1759 T + Q ALFA+E AL+RL+ESWG+ P V GHS+GEL+AAHVSG RG Sbjct: 626 TAYTQAALFALETALFRLVESWGVAPRFVAGHSIGELTAAHVSGVLTLHDAARLVAARGT 685 Query: 1760 LMQALPGGGVMYAVQAGEQELRPLLG---EQVSVAAVNGPGSVVLSGAREAVSVVVDRLA 1816 LMQALP GG M AVQA E E+R L + V++AA NGP S V+SG +AV+ + Sbjct: 686 LMQALPAGGAMVAVQATEDEIRERLAGHEDHVALAAANGPDSTVISGDEQAVTEIAAHWE 745 Query: 1817 AQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED-YGSA 1875 AQGRR +RL VSHAFHS M+ MLE FR VA + P IPV+S VTG L ED S Sbjct: 746 AQGRRTKRLRVSHAFHSPHMDDMLEDFRRVARGLTFHAPRIPVVSTVTGALATEDELRSP 805 Query: 1876 DYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQV-SVVAVPTLRKD 1934 DYWVR +RE VRF +V + G T FVE+G G LT ++++ L + V VP LR Sbjct: 806 DYWVRQVRETVRFCAAVRTLEAEGVTTFVEIGTGGVLTPMVQDCLTTLEEPVLVPLLRTG 865 Query: 1935 RPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 RPE D ++ G R LPTYAF + +WL Sbjct: 866 RPETVALTEGVATAFVHGVPVDRSAFPGAPGTSRADLPTYAFQRQWYWL 914 Score = 759 bits (1960), Expect = 0.0 Identities = 435/944 (46%), Positives = 565/944 (59%), Gaps = 16/944 (1%) Query: 37 RDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGG-DGSQRSADSDTGC 95 +DLG S+ + + L++ G+ + AV+D P+A ++ +L G+Q A+ Sbjct: 3231 QDLGFDSLTAVELRNRLNNATGLRLSATAVFDYPTADALVDFLLDELFGAQEEAELPAPV 3290 Query: 96 AVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGD 155 G ++P+ ++GM+CR+ G V LW ++E A++++P R + + D Sbjct: 3291 PSPA-GAADDPVVIVGMSCRYPGGVGSPEDLWRLVSEGVDAVSDFPTDRGWDVESLYSPD 3349 Query: 156 EQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKT 210 + T G FL + FD FF + P EA D QQRLLLET+W A+E GI P + Sbjct: 3350 PEALGTSYTRSGGFLHEAAEFDPDFFGMSPREALATDAQQRLLLETTWEAIERTGIDPAS 3409 Query: 211 LKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDT 270 L+ S TGVF GV TDY LL G + + + G ++SI + R+SY GP++ +DT Sbjct: 3410 LRGSRTGVFAGVMYTDYGDLLV--GDQFEGYRSNGSAASIASGRVSYTFGFEGPAVTVDT 3467 Query: 271 ACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARA 330 ACSSSLVA H A +SL SGEC LAV G V+ +P + F +S G C+AF A Sbjct: 3468 ACSSSLVALHWAAQSLRSGECSLAVAGGVTVMSTPTTFVEFSRQRGLSADGRCKAFADAA 3527 Query: 331 DGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSA 390 DG+ GEG G++VLERLSDARR G VLAV+ GSAVNQDG SNG+ APN AQ V+ A Sbjct: 3528 DGVGWGEGVGMLVLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQA 3587 Query: 391 CKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEG 450 A + A++D VEAHGTGT++GD IEA AL +G+ R +PL++GS+K NIGH + Sbjct: 3588 LASAGLSAADVDAVEAHGTGTTLGDPIEAQALLATYGQERPEDRPLLLGSVKSNIGHAQA 3647 Query: 451 AAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGV 510 A+G+AG+IK VL ++ G L + + P+ ++ ++ + ++ EWP G PRRAGV Sbjct: 3648 ASGVAGVIKMVLAMRHGVLPRTLHVDEPSSHVDWSAGAVELLTSEAEWPQGEG-PRRAGV 3706 Query: 511 SSFGFGGTNAHXXXXXXXXXXXXXXXXX---GPGVLAWVVSARTAAGVGAQAGRLLEFVR 567 SSFG GTNAH PG LAWV+SAR A + QA RLL V Sbjct: 3707 SSFGVSGTNAHVILEQPGPDAADAAPDATVTDPGALAWVLSARNEAALRCQAARLLSLVA 3766 Query: 568 AGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGG 627 L A D+G+SLVT RS F HRAVV G RD L+ L+ + G G+A G A G Sbjct: 3767 GSDALCARDIGHSLVTGRSSFAHRAVVWGQDRDALVRALSALAVGEADAGLAEG-ASGAG 3825 Query: 628 KTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNT 687 +T F+F GQG+Q LGMG EL A YP LD HL RPLR+VVWG DAELLN Sbjct: 3826 RTAFLFSGQGSQRLGMGWELYARYPVFADAFDAVCAALDEHLERPLRDVVWGEDAELLNQ 3885 Query: 688 TEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGR 747 T +AQ LFA+EVALYRL ESWGMRP V GHS+GE++AAHVSG RGR Sbjct: 3886 TAYAQAGLFAIEVALYRLAESWGMRPDFVAGHSIGEVAAAHVSGVFSLPDACALVAARGR 3945 Query: 748 LMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQG 807 LMQ LP GG M A++A E E+ P L E VS+AAVNGP SVV+SGA +AV + A +G Sbjct: 3946 LMQQLPSGGAMMAIRATEDEVLPHLAEGVSLAAVNGPSSVVISGAEDAVLAIAAHFAGEG 4005 Query: 808 RRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLV-AEDYGSADYW 866 R+ RL VSHAFHS LMEPMLE+FRAV + G P IPV+SN+TG+L E ADYW Sbjct: 4006 RKTTRLRVSHAFHSPLMEPMLEEFRAVVTRLSFGTPTIPVVSNLTGRLAEPEQLAHADYW 4065 Query: 867 VRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEP 926 VRH+REAVRFAD + + G TRF+E+GP G L+++ ES + +V+A P LR+DRPE Sbjct: 4066 VRHVREAVRFADGIQALRAEGVTRFLELGPDGVLSAMARESASDDAVLA-PVLRRDRPEE 4124 Query: 927 FXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 DW AG G + LPTYAF HERFW Sbjct: 4125 TALLGALAQLYVRGAHVDWTVPFAGSGARWADLPTYAFQHERFW 4168 Score = 724 bits (1870), Expect = 0.0 Identities = 428/961 (44%), Positives = 560/961 (58%), Gaps = 29/961 (3%) Query: 33 DLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGG-DGSQRSADS 91 D +DLGL S+ + + L G+ +P V+D P+ + +L G++ + Sbjct: 4928 DRAFQDLGLDSLTAIELRNLLGKATGLRLPATTVFDYPTVDALAAHLLDELFGAETGTAT 4987 Query: 92 DTGCAVLG-NGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAA 150 +T V G ++P+ ++GM+CRF G V LW +A+ A++ +P R G Sbjct: 4988 ETPLPVPGLPSLADDPVVIVGMSCRFPGGVASPEDLWRLVADGVDAVSAFPTDR-GWEID 5046 Query: 151 DWLGDEQE----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGI 206 D E+E T G FL D FD +FF + P EA D QQRLLLET+W ALE AG+ Sbjct: 5047 DTYDPEREGAIATRSGGFLHDAAEFDPEFFGMSPREALTTDAQQRLLLETTWEALERAGM 5106 Query: 207 LPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSL 266 P TL+ S TGVF GV DY LL GR+ + +G + S+ + R+SY GP++ Sbjct: 5107 DPATLRGSRTGVFAGVMYHDYSTLL--SGREFEGYQGSGSAGSVASGRVSYTFGFEGPAV 5164 Query: 267 VIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAF 326 +DTACSSSLVA HLA +SL SGEC LA+ G V+ +P + F G +S G C+AF Sbjct: 5165 TVDTACSSSLVALHLAAQSLRSGECSLALAGGVTVMSTPLTFVEFSRQGGLSADGRCKAF 5224 Query: 327 DARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISV 386 ADG+ EG G++VLERLSDARR G +LA + GSAVNQDG SNG+ APN AQ V Sbjct: 5225 ADAADGVGWAEGAGILVLERLSDARRNGHRILATVRGSAVNQDGASNGLTAPNGPAQQRV 5284 Query: 387 LDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIG 446 + A A + A++D VEAHGTGT++GD IEA AL +G+ R +PL++GS+K NIG Sbjct: 5285 IRQALASAGLSAADVDAVEAHGTGTTLGDPIEAQALLATYGQERPEDRPLLLGSVKSNIG 5344 Query: 447 HLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPR 506 H + A+G+AG+IK VL ++ G L + + P+ ++ ++ + ++ EWP G PR Sbjct: 5345 HAQAASGVAGVIKMVLAMRHGVLPRTLHVDEPSSHVDWSAGAVELLTSEAEWPQGEG-PR 5403 Query: 507 RAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXX---------------GPGVLAWVVSART 551 RAGVSSFG GTNAH G V A ++S R+ Sbjct: 5404 RAGVSSFGISGTNAHVILEQPEPVAAETESITPDTAPDAAEDEAADSGTPVPA-LLSGRS 5462 Query: 552 AAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVE 611 A+ + AQA RLL + DV YSL T RS F HRAV++ A R +LL L+ + E Sbjct: 5463 ASALRAQAARLLSRLDGDPGPRITDVAYSLATGRSAFPHRAVILAANRADLLHSLSALAE 5522 Query: 612 GRPGV-GVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLA 670 G V + GK F+F GQG+Q LGMGREL YP LD HL Sbjct: 5523 GHTEAPAVVAQDRARSGKLAFLFSGQGSQRLGMGRELYGRYPAFAEALDAVCAALDAHLD 5582 Query: 671 RPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVS 730 RPLR+V+WG DAELLN T +AQ LFA+EVAL+RLLESWG+RP ++GHS+GE++AAHV+ Sbjct: 5583 RPLRDVIWGEDAELLNRTGYAQTGLFAIEVALFRLLESWGVRPDHLLGHSIGEIAAAHVA 5642 Query: 731 GXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLS 790 G RGRLMQ LP GG M A++A E E+ P L E VS+AAVNGP SVV+S Sbjct: 5643 GVLSLPDACALVAARGRLMQQLPSGGAMMAIRATEDEVLPHLAEGVSLAAVNGPSSVVVS 5702 Query: 791 GAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISN 850 GA + V + +GR+ RL VSHAFHS LMEPML FRAVAD + P IPV+SN Sbjct: 5703 GAEDEVLALAAHFEEEGRKTTRLRVSHAFHSPLMEPMLADFRAVADGMTYAAPRIPVVSN 5762 Query: 851 VTGQ-LVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLA 909 VTG+ AE+ A+YWV H+REAVRFAD V G T F+E+GP G L++L ES A Sbjct: 5763 VTGRPATAEELCCAEYWVGHVREAVRFADGVGALREQGVTTFLELGPDGSLSALAAESAA 5822 Query: 910 QVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERF 969 SV+A P LRK+RPE DW++ AG G + V LPTYAF HERF Sbjct: 5823 DDSVLA-PVLRKNRPEAPALLTALARLHAQGTPVDWSAAFAGTGARWVDLPTYAFQHERF 5881 Query: 970 W 970 W Sbjct: 5882 W 5882 Score = 681 bits (1757), Expect = 0.0 Identities = 413/970 (42%), Positives = 538/970 (55%), Gaps = 46/970 (4%) Query: 30 VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPS----AHDVIKSVLGGDGS 85 V+ R+ G S+ + + LS G+ +P ++D+P+ A + VLG G Sbjct: 1490 VDAQRAFREQGFDSLMAVDLRNRLSAATGLRLPATLLFDHPTPLAAAACLRSEVLGAAGP 1549 Query: 86 QRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRL 145 + T +EP+A+IGMACRF G VH LW LAE AIT PA R Sbjct: 1550 ATVVQASTAAL-------DEPVAIIGMACRFPGGVHSPEALWRLLAEGGDAITPMPADR- 1601 Query: 146 GAAAADWL----GDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSW 198 D L D Q T Y G FL+ FD FF I P EA MDPQQRLLLET W Sbjct: 1602 -GWDLDRLYHPDPDHQGTSYARGGGFLDGAADFDADFFGISPREALAMDPQQRLLLET-W 1659 Query: 199 AALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYF 258 LE AGI P++L+ S TGVF G ++ DY L + TG + S+++ R+SY Sbjct: 1660 EVLEQAGIDPESLRGSSTGVFAGTNTQDYGTALDAAQDEAGGHRLTGNAMSVVSGRVSYT 1719 Query: 259 LDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVS 318 GP+L +DTACSSSLVA H+A ++L GEC LAV G V+ +P + F ++ Sbjct: 1720 FGFEGPALTVDTACSSSLVALHMAAQALRQGECSLAVAGGVTVMATPSSFVEFARQRGLA 1779 Query: 319 PTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAP 378 P G C+ F A ADG EG G++++ERLSDARR G VLAV+ GSAVNQDG SNG+ AP Sbjct: 1780 PDGRCKPFAAAADGTGWSEGVGLLLVERLSDARRNGHQVLAVVRGSAVNQDGASNGLSAP 1839 Query: 379 NPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMI 438 + +Q V+ A A + +E+D VEAHGTGT++GD IEA AL +G+ R PL++ Sbjct: 1840 SGPSQQRVIRQALANARVAASEVDAVEAHGTGTTLGDPIEAQALLATYGQER----PLLL 1895 Query: 439 GSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEW 498 G++K N+GH + AAG+AG++K VL ++ G L + + P ++ + + ++ E +W Sbjct: 1896 GAVKSNLGHTQAAAGVAGVMKMVLAMRHGMLPRTLHVDEPTGHVDWTAGAVELLTEHTDW 1955 Query: 499 PAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP-----------------G 541 P G PRRA VS+FG GTNAH G Sbjct: 1956 PET-GHPRRAAVSAFGISGTNAHVVLELPAAEQPLVEQPSAAEPDAPATAPDRTPTASDG 2014 Query: 542 VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDE 601 ++SA++ + + AQA RL + L D Y+L+T R+ F HRA V A + Sbjct: 2015 TAPLLLSAKSESALRAQAARLHSHLERDPALRLTDAAYTLMTHRTAFAHRAAVRAADHEA 2074 Query: 602 LLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXX 661 L L + G V +G A G V +F GQG+Q +GMGREL YP Sbjct: 2075 ALRALTALAAGEADPAVDTGTAHTGRDAV-LFSGQGSQRIGMGRELSGRYPVFAEAFDTV 2133 Query: 662 XXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSV 721 LD HL RPLR+VV G D ELLN T +AQ LFA+EVAL+RL+ESWG+RP V GHSV Sbjct: 2134 CAALDEHLDRPLRDVVRGEDEELLNRTVYAQAGLFAIEVALFRLVESWGVRPHYVAGHSV 2193 Query: 722 GELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAV 781 GE++AAHV+G RGRLMQALP GG M A++A E E+ P L + VS+AAV Sbjct: 2194 GEIAAAHVAGVFSLADACALVAARGRLMQALPAGGAMAAIRATEDEVLPHLADSVSIAAV 2253 Query: 782 NGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAG 841 NGP SVV+SGA AV + GR+ RL VSHAFHS LM+PML FRAVA+ + G Sbjct: 2254 NGPSSVVVSGAEHAVLSIAAHFEGAGRKTTRLRVSHAFHSPLMDPMLADFRAVAEGLTYG 2313 Query: 842 RPAIPVISNVTGQLVAED-YGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGL 900 P + V+SNVTGQL D + +YWV H+R AVRFAD + + G TRF+E+GP G L Sbjct: 2314 EPELAVVSNVTGQLATPDQLRTPEYWVTHVRAAVRFADGIRALGAEGVTRFLELGPDGVL 2373 Query: 901 TSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLP 960 ++L ES A V P LRKDR E DW + LAG V LP Sbjct: 2374 SALARES-APDDAVCTPVLRKDRSEAATLLAALTHLHVHGTEIDWTAFLAGRDAHAVDLP 2432 Query: 961 TYAFAHERFW 970 TYAF H+RFW Sbjct: 2433 TYAFQHQRFW 2442 Score = 669 bits (1727), Expect = 0.0 Identities = 400/886 (45%), Positives = 517/886 (58%), Gaps = 24/886 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGD--EQETIY- 161 EP+A++ MACRF G V LW+ L + A++ +P R A + D Q T Y Sbjct: 34 EPLAIVSMACRFPGGVRSPEELWELLRDGVDAVSSFPRNRGWDLDALYHSDPAHQGTSYA 93 Query: 162 --GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVF 219 G FL D FD FF I P EA MDPQQRLLLET+W A+E AGI P++L S TGVF Sbjct: 94 REGGFLHDAGEFDPGFFGISPREALAMDPQQRLLLETAWEAVERAGIDPESLAGSRTGVF 153 Query: 220 VGVSSTDYVRLLFPGGRKPTIWDN---TGGSSSIIANRLSYFLDVNGPSLVIDTACSSSL 276 VG Y G R+ TG SI + R+SY L + GP+L +DTACSSSL Sbjct: 154 VGTGHGGYDA---EGRRRADEVGGHLLTGNHISIASGRISYVLGLEGPALTVDTACSSSL 210 Query: 277 VAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRG 336 VA HLA +L EC +A+V G V+ +P+++ F ++P G C+ F A ADG Sbjct: 211 VALHLAMHALRRDECAMALVGGATVMSTPQMFVEFSRQRGLAPDGRCKPFAAAADGTGWS 270 Query: 337 EGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADI 396 EG G++++ERLSDA R G VLAVL GSAVNQDG SNG+ APN +Q V+ A A + Sbjct: 271 EGVGLLLVERLSDAVRNGYPVLAVLKGSAVNQDGASNGLTAPNGPSQQRVIRQALTGAGL 330 Query: 397 DPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAG 456 ++ID VEAHGTGT++GD +EAHAL +G+ R A +P +GS+K NIGH + AAGIAG Sbjct: 331 AASDIDAVEAHGTGTTLGDPVEAHALLATYGQQRAADRPCGLGSMKSNIGHTQAAAGIAG 390 Query: 457 LIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFG 516 ++K VL ++ G L + + P ++ ++E ++ E + WP+ GRPRRA VSSFG Sbjct: 391 VMKMVLAMRHGHLPRTLHLDEPTGHVDWSEGNARLLAEPEPWPS-AGRPRRAAVSSFGIS 449 Query: 517 GTNAHXXXXXXXXXXXXXXXXXG--PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 574 GTNAH PG L W++SART AG+ AQA RL +R +L+ Sbjct: 450 GTNAHVILEQAPAHEAEPAPEPAARPGALPWILSARTEAGLRAQADRLGRHLRDRADLEP 509 Query: 575 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFP 634 V ++L TR+L EHRAVVV R+E L GL + GR G+ SGVA+ + F+F Sbjct: 510 AAVAHALADTRTLMEHRAVVVAGDREEFLRGLDALAAGRTANGLVSGVAVKAA-SAFLFA 568 Query: 635 GQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVW----GADAELLNTTEF 690 GQG+Q GMGREL A +P ELD HL RPLR++V+ A+A LL+ T + Sbjct: 569 GQGSQRPGMGRELHAAHPVFATAFDAVCAELDPHLDRPLRDIVFAEEGSAEAALLDQTAY 628 Query: 691 AQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQ 750 Q ALFA+E AL+RL+ESWG+ P V GHS+GEL+AAHVSG RG LMQ Sbjct: 629 TQAALFALETALFRLVESWGVAPRFVAGHSIGELTAAHVSGVLTLHDAARLVAARGTLMQ 688 Query: 751 ALPGGGVMYAVQAGEQELRPLLG---EQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQG 807 ALP GG M AVQA E E+R L + V++AA NGP S V+SG +AV+ + AQG Sbjct: 689 ALPAGGAMVAVQATEDEIRERLAGHEDHVALAAANGPDSTVISGDEQAVTEIAAHWEAQG 748 Query: 808 RRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED-YGSADYW 866 RR +RL VSHAFHS M+ MLE FR VA + P IPV+S VTG L ED S DYW Sbjct: 749 RRTKRLRVSHAFHSPHMDDMLEDFRRVARGLTFHAPRIPVVSTVTGALATEDELRSPDYW 808 Query: 867 VRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQV-SVVAVPTLRKDRPE 925 VR +RE VRF +V + G T FVE+G G LT ++++ L + V VP LR RPE Sbjct: 809 VRQVRETVRFCAAVRTLEAEGVTTFVEIGTGGVLTPMVQDCLTTLEEPVLVPLLRTGRPE 868 Query: 926 PFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 D ++ G R LPTYAF + +WL Sbjct: 869 TVALTEGVATAFVHGVPVDRSAFPGAPGTSRADLPTYAFQRQWYWL 914 Score = 84.0 bits (206), Expect = 3e-13 Identities = 47/107 (43%), Positives = 62/107 (57%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GLS AE + VL V A VLG A ++D +AF D G SL+AVELRNRL + Sbjct: 6623 RLTGLSAAEGREVVLGAVRSQIAGVLGHAEATEIDQDRAFLDLGFDSLTAVELRNRLGAV 6682 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDE 1116 TG+ L AT FDYPTP +L HL + + + P A + R+++ Sbjct: 6683 TGIRLPATLLFDYPTPAELVAHLHARIAPEPTVGPEALLGELERMEK 6729 Score = 84.0 bits (206), Expect = 3e-13 Identities = 48/106 (45%), Positives = 62/106 (58%), Gaps = 3/106 (2%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GLS AE + VL V A VLG A ++D +AF D G SL+AVELRNRL + Sbjct: 6623 RLTGLSAAEGREVVLGAVRSQIAGVLGHAEATEIDQDRAFLDLGFDSLTAVELRNRLGAV 6682 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQ---NPTGATPELDRVD 2124 TG+ L AT FDYPTP +L HL + + + P EL+R++ Sbjct: 6683 TGIRLPATLLFDYPTPAELVAHLHARIAPEPTVGPEALLGELERME 6728 Score = 79.7 bits (195), Expect = 5e-12 Identities = 45/87 (51%), Positives = 54/87 (62%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GLS AE++ A+L +V A VLG G + +AF D GL SL+A+ELRN L Sbjct: 4892 RLAGLSTAERREALLDVVRAQIATVLGHAGPETIAPDRAFQDLGLDSLTAIELRNLLGKA 4951 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L ATT FDYPT LA HLL L Sbjct: 4952 TGLRLPATTVFDYPTVDALAAHLLDEL 4978 Score = 72.8 bits (177), Expect = 6e-10 Identities = 39/87 (44%), Positives = 49/87 (56%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL G E++ +L +V A VLG +++ + F D G SL+AVELRNRL Sbjct: 3191 RLSGRGTVERREVLLDLVRAQIAVVLGHANPETIESTRVFQDLGFDSLTAVELRNRLNNA 3250 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ LSAT FDYPT L D LL L Sbjct: 3251 TGLRLSATAVFDYPTADALVDFLLDEL 3277 Score = 71.6 bits (174), Expect = 1e-09 Identities = 41/87 (47%), Positives = 50/87 (57%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 R+ L AEQ+ A L MV E A VLG +DA +AF + G SL AV+LRNRL Sbjct: 1457 RIGALPPAEQEKAFLTMVREEAARVLGHPSPDTVDAQRAFREQGFDSLMAVDLRNRLSAA 1516 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L AT FD+PTP A L S + Sbjct: 1517 TGLRLPATLLFDHPTPLAAAACLRSEV 1543 >tr|Q7TXK8|Q7TXK8_MYCBO Tax_Id=1765 (pks1)SubName: Full=PROBABLE POLYKETIDE SYNTHASE PKS1;[Mycobacterium bovis] Length = 2112 Score = 1045 bits (2702), Expect = 0.0 Identities = 545/910 (59%), Positives = 642/910 (70%), Gaps = 18/910 (1%) Query: 1089 ADHLLSHLHHQNRSAPAAAVRTRVRI-------DEPIAIVGMGCRYPGGVSSPAQLWQLV 1141 AD L H + TR R+ EP+A+VG+GCR+PGGV P LW +V Sbjct: 13 ADQQSEKLFHYLKKVAVELDETRARLREYEQRATEPVAVVGIGCRFPGGVDGPDGLWDVV 72 Query: 1142 ASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALA 1201 ++G DV+ EFP DRGWD+E L+DPDPDA GKTYTR G F+ D FD GFFGI+P E LA Sbjct: 73 SAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYTRWGAFLDDATGFDAGFFGIAPSEVLA 132 Query: 1202 MDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG-LGTSQAQWYADTGHIT 1260 MDPQQRL+LE SWEALE AGIDP +LRGS+TGV+ GI+ YG T Q Y TG Sbjct: 133 MDPQQRLMLEVSWEALEHAGIDPLSLRGSATGVYTGIFAASYGNRDTGGLQGYGLTGTSI 192 Query: 1261 SVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIF 1320 SVASGR+SY LGL GPA+SVDTACSSSLVA+H A +SLR+GECDLALAGG TV+ PSIF Sbjct: 193 SVASGRVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIF 252 Query: 1321 IGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQ 1380 +GFSRQRGLA DGRCKAFA AADGTG+ EGAG++VL+RLSDARR G VLA++ GSAVNQ Sbjct: 253 VGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRLGHSVLAVVRGSAVNQ 312 Query: 1381 DGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGR 1440 DGASNGLTAP+G AQQRVI AAL++AG++ ADVDVVEAHGT T LGDPIEAQALL+TYG+ Sbjct: 313 DGASNGLTAPNGLAQQRVIQAALANAGLSAADVDVVEAHGTATTLGDPIEAQALLSTYGQ 372 Query: 1441 DHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGT 1500 + PLW+GSIKSNMGH+QAAAGVAGVIKMV+AMRH ++PATLH+D+PS VDW+ G Sbjct: 373 GRPAEQPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGA 432 Query: 1501 VQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXG--------P 1552 V +LTEAREW +V GRPRRA VSSFG+SGTNAH P Sbjct: 433 VSVLTEAREW-SVDGRPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVEASESTGGPRP 491 Query: 1553 GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRD 1612 ++ WV+SAR+A + AQAGRL+ V+A LD DVG SL +RS+FEHRAVVVGA R+ Sbjct: 492 SMVPWVISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSL-ASRSVFEHRAVVVGASRE 550 Query: 1613 ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXX 1672 +L+AGLA + G PG GVA G GKTV VFPGQGAQ +GMGREL P Sbjct: 551 QLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQGAQRIGMGRELYGELPVFAQAFDA 610 Query: 1673 XXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHS 1732 ELDRHL PLR+V+WGADA+LL++TEFAQPALFAVEVA + +L WG+ P VMGHS Sbjct: 611 VADELDRHLRLPLRDVIWGADADLLDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHS 670 Query: 1733 VGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAA 1792 VGEL+AAH +G RGRLMQALP GG M AV A E E+ PLLGE V +AA Sbjct: 671 VGELAAAHAAGVLTLADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEGVGIAA 730 Query: 1793 VNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA 1852 +N P SVV+SGA+ A + + DR AAQGRRV +LAVSHAFHS LMEPMLE+F VA V A Sbjct: 731 INAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEPMLEEFARVAARVQA 790 Query: 1853 GRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGL 1912 P + ++SNVTG+L D+GSA YWV H+R VRFADS + GAT F+E GP GL Sbjct: 791 REPQLGLVSNVTGELAGPDFGSAQYWVDHVRRPVRFADSARHLQTLGATHFIEAGPGSGL 850 Query: 1913 TSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLP 1972 T IE+SLA + V L KDRPE W++V AG GG+RV LP Sbjct: 851 TGSIEQSLAPAEAMVVSMLGKDRPELASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLP 910 Query: 1973 TYAFAHERFW 1982 TYAF RFW Sbjct: 911 TYAFQRRRFW 920 Score = 805 bits (2080), Expect = 0.0 Identities = 443/879 (50%), Positives = 554/879 (63%), Gaps = 18/879 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE-----T 159 EP+AV+G+ CRF G V G LWD ++ + ++E+P R + D T Sbjct: 47 EPVAVVGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYT 106 Query: 160 IYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVF 219 +G FL+D GFD FF I P E MDPQQRL+LE SW ALEHAGI P +L+ S TGV+ Sbjct: 107 RWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHAGIDPLSLRGSATGVY 166 Query: 220 VGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAA 279 G+ + Y GG + + TG S S+ + R+SY L + GP++ +DTACSSSLVA Sbjct: 167 TGIFAASYGNR-DTGGLQG--YGLTGTSISVASGRVSYVLGLQGPAVSVDTACSSSLVAI 223 Query: 280 HLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGC 339 H A SL SGECDLA+ G V+ P ++ GF ++ G C+AF A ADG GEG Sbjct: 224 HWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGA 283 Query: 340 GVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPA 399 GVVVLERLSDARR G +VLAV+ GSAVNQDG SNG+ APN AQ V+ +A A + A Sbjct: 284 GVVVLERLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAA 343 Query: 400 EIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIK 459 ++D VEAHGT T++GD IEA AL +G+GR A +PL +GSIK N+GH + AAG+AG+IK Sbjct: 344 DVDVVEAHGTATTLGDPIEAQALLSTYGQGRPAEQPLWVGSIKSNMGHTQAAAGVAGVIK 403 Query: 460 TVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTN 519 V ++ G + + + P+P + + ++V+ E +EW +V GRPRRA VSSFG GTN Sbjct: 404 MVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREW-SVDGRPRRAAVSSFGISGTN 462 Query: 520 AHXXXXXXXXXXXXXXXXXG--------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRE 571 AH P ++ WV+SAR+A + AQAGRL+ V+A Sbjct: 463 AHLILEEAPVPAPAEAPVEASESTGGPRPSMVPWVISARSAEALTAQAGRLMAHVQANPG 522 Query: 572 LDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVF 631 LD DVG SL + RS+FEHRAVVVGA R++L+AGLA + G PG GVA G GKTV Sbjct: 523 LDPIDVGCSLAS-RSVFEHRAVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVV 581 Query: 632 VFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFA 691 VFPGQGAQ +GMGREL P ELDRHL PLR+V+WGADA+LL++TEFA Sbjct: 582 VFPGQGAQRIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLLDSTEFA 641 Query: 692 QPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA 751 QPALFAVEVA + +L WG+ P VMGHSVGEL+AAH +G RGRLMQA Sbjct: 642 QPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAAGVLTLADAAMLVVARGRLMQA 701 Query: 752 LPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 LP GG M AV A E E+ PLLGE V +AA+N P SVV+SGA+ A + + DR AAQGRRV Sbjct: 702 LPAGGAMVAVAASEDEVEPLLGEGVGIAAINAPESVVISGAQAAANAIADRFAAQGRRVH 761 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 +LAVSHAFHS LMEPMLE+F VA V A P + ++SNVTG+L D+GSA YWV H+R Sbjct: 762 QLAVSHAFHSPLMEPMLEEFARVAARVQAREPQLGLVSNVTGELAGPDFGSAQYWVDHVR 821 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXX 931 VRFADS + GAT F+E GP GLT IE+SLA + V L KDRPE Sbjct: 822 RPVRFADSARHLQTLGATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGKDRPELASALG 881 Query: 932 XXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 W++V AG GG+RV LPTYAF RFW Sbjct: 882 AAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFW 920 Score = 89.0 bits (219), Expect = 8e-15 Identities = 45/93 (48%), Positives = 58/93 (62%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL+ EQ ++ +VC AAVLGR A +D F D G SL+AVELRNRLKT Sbjct: 1999 RLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTA 2058 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPT 2114 TG+TL T FD+PTPT +A+++ + PT Sbjct: 2059 TGLTLPPTVIFDHPTPTAVAEYVAQQMSGSRPT 2091 Score = 86.3 bits (212), Expect = 5e-14 Identities = 48/110 (43%), Positives = 65/110 (59%), Gaps = 3/110 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL+ EQ ++ +VC AAVLGR A +D F D G SL+AVELRNRLKT Sbjct: 1999 RLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTA 2058 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIA 1119 TG+TL T FD+PTPT +A+++ + + S P + ++ EP A Sbjct: 2059 TGLTLPPTVIFDHPTPTAVAEYVAQQM---SGSRPTESGDPTSQVVEPAA 2105 >tr|C1AG62|C1AG62_MYCBT Tax_Id=561275 (pks1)SubName: Full=Putative polyketide synthase;[Mycobacterium bovis] Length = 2112 Score = 1045 bits (2702), Expect = 0.0 Identities = 545/910 (59%), Positives = 642/910 (70%), Gaps = 18/910 (1%) Query: 1089 ADHLLSHLHHQNRSAPAAAVRTRVRI-------DEPIAIVGMGCRYPGGVSSPAQLWQLV 1141 AD L H + TR R+ EP+A+VG+GCR+PGGV P LW +V Sbjct: 13 ADQQSEKLFHYLKKVAVELDETRARLREYEQRATEPVAVVGIGCRFPGGVDGPDGLWDVV 72 Query: 1142 ASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALA 1201 ++G DV+ EFP DRGWD+E L+DPDPDA GKTYTR G F+ D FD GFFGI+P E LA Sbjct: 73 SAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYTRWGAFLDDATGFDAGFFGIAPSEVLA 132 Query: 1202 MDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG-LGTSQAQWYADTGHIT 1260 MDPQQRL+LE SWEALE AGIDP +LRGS+TGV+ GI+ YG T Q Y TG Sbjct: 133 MDPQQRLMLEVSWEALEHAGIDPLSLRGSATGVYTGIFAASYGNRDTGGLQGYGLTGTSI 192 Query: 1261 SVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIF 1320 SVASGR+SY LGL GPA+SVDTACSSSLVA+H A +SLR+GECDLALAGG TV+ PSIF Sbjct: 193 SVASGRVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIF 252 Query: 1321 IGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQ 1380 +GFSRQRGLA DGRCKAFA AADGTG+ EGAG++VL+RLSDARR G VLA++ GSAVNQ Sbjct: 253 VGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRLGHSVLAVVRGSAVNQ 312 Query: 1381 DGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGR 1440 DGASNGLTAP+G AQQRVI AAL++AG++ ADVDVVEAHGT T LGDPIEAQALL+TYG+ Sbjct: 313 DGASNGLTAPNGLAQQRVIQAALANAGLSAADVDVVEAHGTATTLGDPIEAQALLSTYGQ 372 Query: 1441 DHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGT 1500 + PLW+GSIKSNMGH+QAAAGVAGVIKMV+AMRH ++PATLH+D+PS VDW+ G Sbjct: 373 GRPAEQPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGA 432 Query: 1501 VQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXG--------P 1552 V +LTEAREW +V GRPRRA VSSFG+SGTNAH P Sbjct: 433 VSVLTEAREW-SVDGRPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVEASESTGGPRP 491 Query: 1553 GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRD 1612 ++ WV+SAR+A + AQAGRL+ V+A LD DVG SL +RS+FEHRAVVVGA R+ Sbjct: 492 SMVPWVISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSL-ASRSVFEHRAVVVGASRE 550 Query: 1613 ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXX 1672 +L+AGLA + G PG GVA G GKTV VFPGQGAQ +GMGREL P Sbjct: 551 QLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQGAQRIGMGRELYGELPVFAQAFDA 610 Query: 1673 XXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHS 1732 ELDRHL PLR+V+WGADA+LL++TEFAQPALFAVEVA + +L WG+ P VMGHS Sbjct: 611 VADELDRHLRLPLRDVIWGADADLLDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHS 670 Query: 1733 VGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAA 1792 VGEL+AAH +G RGRLMQALP GG M AV A E E+ PLLGE V +AA Sbjct: 671 VGELAAAHAAGVLTLADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEGVGIAA 730 Query: 1793 VNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA 1852 +N P SVV+SGA+ A + + DR AAQGRRV +LAVSHAFHS LMEPMLE+F VA V A Sbjct: 731 INAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEPMLEEFARVAARVQA 790 Query: 1853 GRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGL 1912 P + ++SNVTG+L D+GSA YWV H+R VRFADS + GAT F+E GP GL Sbjct: 791 REPQLGLVSNVTGELAGPDFGSAQYWVDHVRRPVRFADSARHLQTLGATHFIEAGPGSGL 850 Query: 1913 TSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLP 1972 T IE+SLA + V L KDRPE W++V AG GG+RV LP Sbjct: 851 TGSIEQSLAPAEAMVVSMLGKDRPELASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLP 910 Query: 1973 TYAFAHERFW 1982 TYAF RFW Sbjct: 911 TYAFQRRRFW 920 Score = 805 bits (2080), Expect = 0.0 Identities = 443/879 (50%), Positives = 554/879 (63%), Gaps = 18/879 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE-----T 159 EP+AV+G+ CRF G V G LWD ++ + ++E+P R + D T Sbjct: 47 EPVAVVGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYT 106 Query: 160 IYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVF 219 +G FL+D GFD FF I P E MDPQQRL+LE SW ALEHAGI P +L+ S TGV+ Sbjct: 107 RWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHAGIDPLSLRGSATGVY 166 Query: 220 VGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAA 279 G+ + Y GG + + TG S S+ + R+SY L + GP++ +DTACSSSLVA Sbjct: 167 TGIFAASYGNR-DTGGLQG--YGLTGTSISVASGRVSYVLGLQGPAVSVDTACSSSLVAI 223 Query: 280 HLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGC 339 H A SL SGECDLA+ G V+ P ++ GF ++ G C+AF A ADG GEG Sbjct: 224 HWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGA 283 Query: 340 GVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPA 399 GVVVLERLSDARR G +VLAV+ GSAVNQDG SNG+ APN AQ V+ +A A + A Sbjct: 284 GVVVLERLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAA 343 Query: 400 EIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIK 459 ++D VEAHGT T++GD IEA AL +G+GR A +PL +GSIK N+GH + AAG+AG+IK Sbjct: 344 DVDVVEAHGTATTLGDPIEAQALLSTYGQGRPAEQPLWVGSIKSNMGHTQAAAGVAGVIK 403 Query: 460 TVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTN 519 V ++ G + + + P+P + + ++V+ E +EW +V GRPRRA VSSFG GTN Sbjct: 404 MVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREW-SVDGRPRRAAVSSFGISGTN 462 Query: 520 AHXXXXXXXXXXXXXXXXXG--------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRE 571 AH P ++ WV+SAR+A + AQAGRL+ V+A Sbjct: 463 AHLILEEAPVPAPAEAPVEASESTGGPRPSMVPWVISARSAEALTAQAGRLMAHVQANPG 522 Query: 572 LDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVF 631 LD DVG SL + RS+FEHRAVVVGA R++L+AGLA + G PG GVA G GKTV Sbjct: 523 LDPIDVGCSLAS-RSVFEHRAVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVV 581 Query: 632 VFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFA 691 VFPGQGAQ +GMGREL P ELDRHL PLR+V+WGADA+LL++TEFA Sbjct: 582 VFPGQGAQRIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLLDSTEFA 641 Query: 692 QPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA 751 QPALFAVEVA + +L WG+ P VMGHSVGEL+AAH +G RGRLMQA Sbjct: 642 QPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAAGVLTLADAAMLVVARGRLMQA 701 Query: 752 LPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 LP GG M AV A E E+ PLLGE V +AA+N P SVV+SGA+ A + + DR AAQGRRV Sbjct: 702 LPAGGAMVAVAASEDEVEPLLGEGVGIAAINAPESVVISGAQAAANAIADRFAAQGRRVH 761 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 +LAVSHAFHS LMEPMLE+F VA V A P + ++SNVTG+L D+GSA YWV H+R Sbjct: 762 QLAVSHAFHSPLMEPMLEEFARVAARVQAREPQLGLVSNVTGELAGPDFGSAQYWVDHVR 821 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXX 931 VRFADS + GAT F+E GP GLT IE+SLA + V L KDRPE Sbjct: 822 RPVRFADSARHLQTLGATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGKDRPELASALG 881 Query: 932 XXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 W++V AG GG+RV LPTYAF RFW Sbjct: 882 AAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFW 920 Score = 89.0 bits (219), Expect = 8e-15 Identities = 45/93 (48%), Positives = 58/93 (62%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL+ EQ ++ +VC AAVLGR A +D F D G SL+AVELRNRLKT Sbjct: 1999 RLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTA 2058 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPT 2114 TG+TL T FD+PTPT +A+++ + PT Sbjct: 2059 TGLTLPPTVIFDHPTPTAVAEYVAQQMSGSRPT 2091 Score = 86.3 bits (212), Expect = 5e-14 Identities = 48/110 (43%), Positives = 65/110 (59%), Gaps = 3/110 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL+ EQ ++ +VC AAVLGR A +D F D G SL+AVELRNRLKT Sbjct: 1999 RLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTA 2058 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIA 1119 TG+TL T FD+PTPT +A+++ + + S P + ++ EP A Sbjct: 2059 TGLTLPPTVIFDHPTPTAVAEYVAQQM---SGSRPTESGDPTSQVVEPAA 2105 >tr|A1KMU1|A1KMU1_MYCBP Tax_Id=410289 (pks1)SubName: Full=Probable polyketide synthase pks1;[Mycobacterium bovis] Length = 2112 Score = 1045 bits (2702), Expect = 0.0 Identities = 545/910 (59%), Positives = 642/910 (70%), Gaps = 18/910 (1%) Query: 1089 ADHLLSHLHHQNRSAPAAAVRTRVRI-------DEPIAIVGMGCRYPGGVSSPAQLWQLV 1141 AD L H + TR R+ EP+A+VG+GCR+PGGV P LW +V Sbjct: 13 ADQQSEKLFHYLKKVAVELDETRARLREYEQRATEPVAVVGIGCRFPGGVDGPDGLWDVV 72 Query: 1142 ASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALA 1201 ++G DV+ EFP DRGWD+E L+DPDPDA GKTYTR G F+ D FD GFFGI+P E LA Sbjct: 73 SAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYTRWGAFLDDATGFDAGFFGIAPSEVLA 132 Query: 1202 MDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG-LGTSQAQWYADTGHIT 1260 MDPQQRL+LE SWEALE AGIDP +LRGS+TGV+ GI+ YG T Q Y TG Sbjct: 133 MDPQQRLMLEVSWEALEHAGIDPLSLRGSATGVYTGIFAASYGNRDTGGLQGYGLTGTSI 192 Query: 1261 SVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIF 1320 SVASGR+SY LGL GPA+SVDTACSSSLVA+H A +SLR+GECDLALAGG TV+ PSIF Sbjct: 193 SVASGRVSYVLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIF 252 Query: 1321 IGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQ 1380 +GFSRQRGLA DGRCKAFA AADGTG+ EGAG++VL+RLSDARR G VLA++ GSAVNQ Sbjct: 253 VGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRLGHSVLAVVRGSAVNQ 312 Query: 1381 DGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGR 1440 DGASNGLTAP+G AQQRVI AAL++AG++ ADVDVVEAHGT T LGDPIEAQALL+TYG+ Sbjct: 313 DGASNGLTAPNGLAQQRVIQAALANAGLSAADVDVVEAHGTATTLGDPIEAQALLSTYGQ 372 Query: 1441 DHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGT 1500 + PLW+GSIKSNMGH+QAAAGVAGVIKMV+AMRH ++PATLH+D+PS VDW+ G Sbjct: 373 GRPAEQPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHGVMPATLHVDEPSPRVDWTSGA 432 Query: 1501 VQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXG--------P 1552 V +LTEAREW +V GRPRRA VSSFG+SGTNAH P Sbjct: 433 VSVLTEAREW-SVDGRPRRAAVSSFGISGTNAHLILEEAPVPAPAEAPVEASESTGGPRP 491 Query: 1553 GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRD 1612 ++ WV+SAR+A + AQAGRL+ V+A LD DVG SL +RS+FEHRAVVVGA R+ Sbjct: 492 SMVPWVISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSL-ASRSVFEHRAVVVGASRE 550 Query: 1613 ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXX 1672 +L+AGLA + G PG GVA G GKTV VFPGQGAQ +GMGREL P Sbjct: 551 QLIAGLAGLAAGEPGAGVAVGQPGSVGKTVVVFPGQGAQRIGMGRELYGELPVFAQAFDA 610 Query: 1673 XXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHS 1732 ELDRHL PLR+V+WGADA+LL++TEFAQPALFAVEVA + +L WG+ P VMGHS Sbjct: 611 VADELDRHLRLPLRDVIWGADADLLDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHS 670 Query: 1733 VGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAA 1792 VGEL+AAH +G RGRLMQALP GG M AV A E E+ PLLGE V +AA Sbjct: 671 VGELAAAHAAGVLTLADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEGVGIAA 730 Query: 1793 VNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA 1852 +N P SVV+SGA+ A + + DR AAQGRRV +LAVSHAFHS LMEPMLE+F VA V A Sbjct: 731 INAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEPMLEEFARVAARVQA 790 Query: 1853 GRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGL 1912 P + ++SNVTG+L D+GSA YWV H+R VRFADS + GAT F+E GP GL Sbjct: 791 REPQLGLVSNVTGELAGPDFGSAQYWVDHVRRPVRFADSARHLQTLGATHFIEAGPGSGL 850 Query: 1913 TSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLP 1972 T IE+SLA + V L KDRPE W++V AG GG+RV LP Sbjct: 851 TGSIEQSLAPAEAMVVSMLGKDRPELASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLP 910 Query: 1973 TYAFAHERFW 1982 TYAF RFW Sbjct: 911 TYAFQRRRFW 920 Score = 805 bits (2080), Expect = 0.0 Identities = 443/879 (50%), Positives = 554/879 (63%), Gaps = 18/879 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE-----T 159 EP+AV+G+ CRF G V G LWD ++ + ++E+P R + D T Sbjct: 47 EPVAVVGIGCRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTYT 106 Query: 160 IYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVF 219 +G FL+D GFD FF I P E MDPQQRL+LE SW ALEHAGI P +L+ S TGV+ Sbjct: 107 RWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHAGIDPLSLRGSATGVY 166 Query: 220 VGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAA 279 G+ + Y GG + + TG S S+ + R+SY L + GP++ +DTACSSSLVA Sbjct: 167 TGIFAASYGNR-DTGGLQG--YGLTGTSISVASGRVSYVLGLQGPAVSVDTACSSSLVAI 223 Query: 280 HLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGC 339 H A SL SGECDLA+ G V+ P ++ GF ++ G C+AF A ADG GEG Sbjct: 224 HWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGA 283 Query: 340 GVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPA 399 GVVVLERLSDARR G +VLAV+ GSAVNQDG SNG+ APN AQ V+ +A A + A Sbjct: 284 GVVVLERLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAA 343 Query: 400 EIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIK 459 ++D VEAHGT T++GD IEA AL +G+GR A +PL +GSIK N+GH + AAG+AG+IK Sbjct: 344 DVDVVEAHGTATTLGDPIEAQALLSTYGQGRPAEQPLWVGSIKSNMGHTQAAAGVAGVIK 403 Query: 460 TVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTN 519 V ++ G + + + P+P + + ++V+ E +EW +V GRPRRA VSSFG GTN Sbjct: 404 MVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREW-SVDGRPRRAAVSSFGISGTN 462 Query: 520 AHXXXXXXXXXXXXXXXXXG--------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRE 571 AH P ++ WV+SAR+A + AQAGRL+ V+A Sbjct: 463 AHLILEEAPVPAPAEAPVEASESTGGPRPSMVPWVISARSAEALTAQAGRLMAHVQANPG 522 Query: 572 LDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVF 631 LD DVG SL + RS+FEHRAVVVGA R++L+AGLA + G PG GVA G GKTV Sbjct: 523 LDPIDVGCSLAS-RSVFEHRAVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKTVV 581 Query: 632 VFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFA 691 VFPGQGAQ +GMGREL P ELDRHL PLR+V+WGADA+LL++TEFA Sbjct: 582 VFPGQGAQRIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGADADLLDSTEFA 641 Query: 692 QPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA 751 QPALFAVEVA + +L WG+ P VMGHSVGEL+AAH +G RGRLMQA Sbjct: 642 QPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAAGVLTLADAAMLVVARGRLMQA 701 Query: 752 LPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 LP GG M AV A E E+ PLLGE V +AA+N P SVV+SGA+ A + + DR AAQGRRV Sbjct: 702 LPAGGAMVAVAASEDEVEPLLGEGVGIAAINAPESVVISGAQAAANAIADRFAAQGRRVH 761 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIR 871 +LAVSHAFHS LMEPMLE+F VA V A P + ++SNVTG+L D+GSA YWV H+R Sbjct: 762 QLAVSHAFHSPLMEPMLEEFARVAARVQAREPQLGLVSNVTGELAGPDFGSAQYWVDHVR 821 Query: 872 EAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXX 931 VRFADS + GAT F+E GP GLT IE+SLA + V L KDRPE Sbjct: 822 RPVRFADSARHLQTLGATHFIEAGPGSGLTGSIEQSLAPAEAMVVSMLGKDRPELASALG 881 Query: 932 XXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 W++V AG GG+RV LPTYAF RFW Sbjct: 882 AAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFW 920 Score = 89.0 bits (219), Expect = 8e-15 Identities = 45/93 (48%), Positives = 58/93 (62%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL+ EQ ++ +VC AAVLGR A +D F D G SL+AVELRNRLKT Sbjct: 1999 RLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTA 2058 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPT 2114 TG+TL T FD+PTPT +A+++ + PT Sbjct: 2059 TGLTLPPTVIFDHPTPTAVAEYVAQQMSGSRPT 2091 Score = 86.3 bits (212), Expect = 5e-14 Identities = 48/110 (43%), Positives = 65/110 (59%), Gaps = 3/110 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL+ EQ ++ +VC AAVLGR A +D F D G SL+AVELRNRLKT Sbjct: 1999 RLHGLAADEQLELLVGLVCLQAAAVLGRPSAEDVDPDTEFGDLGFDSLTAVELRNRLKTA 2058 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIA 1119 TG+TL T FD+PTPT +A+++ + + S P + ++ EP A Sbjct: 2059 TGLTLPPTVIFDHPTPTAVAEYVAQQM---SGSRPTESGDPTSQVVEPAA 2105 >tr|Q9CD81|Q9CD81_MYCLE Tax_Id=1769 SubName: Full=Putative polyketide synthase;[Mycobacterium leprae] Length = 2103 Score = 1032 bits (2668), Expect = 0.0 Identities = 532/874 (60%), Positives = 634/874 (72%), Gaps = 6/874 (0%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EP+A+VG+GCR+PGGV SP +LW +V+ DV+ EFP DRGWD++ LFDPDPDA GK Sbjct: 39 RATEPVAVVGIGCRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGK 98 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 TYTR G F+ D A FD GFFGI+P E LAMDPQQRL+LE SWEALE AGIDP +LRGS+T Sbjct: 99 TYTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSAT 158 Query: 1233 GVFVGIYGDGYGL-GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 GVF GI+ YG T Q Y TG SVASGR+SY LGL GPA+SVDTACSSSLVA+ Sbjct: 159 GVFTGIFAPSYGSRDTGGLQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTACSSSLVAI 218 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 H A +SLR+GECDLALAGG TV+ PSIF+GFSRQRGLA DGRCKAFA AADGTG+ EGA Sbjct: 219 HWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFARAADGTGWGEGA 278 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 G++VL+RLSDA+R G VLA++ GSAVNQDGASNGLTAP+G AQQRVI AAL++AG++ A Sbjct: 279 GVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSA 338 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 DVDVVEAHGT T LGDPIEAQALLATYG+ D PLW+GSIKSNMGH+QAAAGVAGVIK Sbjct: 339 DVDVVEAHGTATTLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAGVAGVIK 398 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV+AMRH ++PATLH+D+PS VDW+ G V +LTEAR+W +V GRPRRAGVSSFG+SGTN Sbjct: 399 MVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDW-SVEGRPRRAGVSSFGISGTN 457 Query: 1532 AHXXXXXXXXXXXXXXXXXGP---GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 1588 AH V+ WVVS R+ A + AQA RL +V+A E+D D Sbjct: 458 AHVILEEAPTPVEASYSTADQQRLSVVPWVVSGRSTAALMAQASRLAFYVQADPEVDPVD 517 Query: 1589 VGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQ 1648 VG +L RS+FEHRAVVVG R++L+AGLA + G G GVA G A P GKTV VFPGQ Sbjct: 518 VGCAL-AARSVFEHRAVVVGESREQLIAGLAGLAVGESGAGVAIGQAAPLGKTVVVFPGQ 576 Query: 1649 GAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALF 1708 GAQ +GMGRELC+ P ELDRH+ PLR+VVWGADA LL++TEFAQPALF Sbjct: 577 GAQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGLLDSTEFAQPALF 636 Query: 1709 AVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGG 1768 AVEVAL+ +L+ WG++P VMGHS+GEL+AA+V+G RGRLMQ++P GG Sbjct: 637 AVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGRLMQSMPAGG 696 Query: 1769 VMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVS 1828 M+AV A E E+ LLGE V +AA+N P SVV+SG + AVS + D+ AAQGRRV +LAVS Sbjct: 697 TMWAVAASEDEVVSLLGEGVGIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVS 756 Query: 1829 HAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRF 1888 HAFHS LMEPMLE+F VA +V +P I ++SNVTG+L D+GS YW H+ AVRF Sbjct: 757 HAFHSPLMEPMLEEFVRVAAQVEVRKPQIGLVSNVTGELAGPDFGSPQYWGEHVSRAVRF 816 Query: 1889 ADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXX 1948 DS + GAT F+E GP+ GL IE+SLA V V + KDRPE Sbjct: 817 VDSARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAVVVSMMGKDRPELASVLGAAGQL 876 Query: 1949 XXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 +W +V AG +RV LPTYAF RFW Sbjct: 877 FATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFW 910 Score = 781 bits (2016), Expect = 0.0 Identities = 432/876 (49%), Positives = 552/876 (63%), Gaps = 17/876 (1%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE------ 158 EP+AV+G+ CRF G V LWD ++E + ++E+P R D L D Sbjct: 42 EPVAVVGIGCRFPGGVDSPDRLWDVVSECRDVVSEFPTDR--GWDVDGLFDPDPDAEGKT 99 Query: 159 -TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 T +G FL+D GFD FF I P E MDPQQRL+LE SW ALE+AGI P +L+ S TG Sbjct: 100 YTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATG 159 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ + Y GG + + TG + S+ + R+SY L + GP++ +DTACSSSLV Sbjct: 160 VFTGIFAPSYGSR-DTGGLQG--YGLTGTAVSVASGRVSYVLGLEGPAVSVDTACSSSLV 216 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H A SL SGECDLA+ G V+ P ++ GF ++ G C+AF ADG GE Sbjct: 217 AIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFARAADGTGWGE 276 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G GVVVLERLSDA+R G TVLAV+ GSAVNQDG SNG+ APN AQ V+ +A A + Sbjct: 277 GAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLS 336 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGL 457 A++D VEAHGT T++GD IEA AL +G+GR A +PL +GSIK N+GH + AAG+AG+ Sbjct: 337 SADVDVVEAHGTATTLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAGVAGV 396 Query: 458 IKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGG 517 IK V ++ + + + P+P + + ++V+ E ++W +V GRPRRAGVSSFG G Sbjct: 397 IKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDW-SVEGRPRRAGVSSFGISG 455 Query: 518 TNAHXXXXXXXXXXXXXXXXXGP---GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 574 TNAH V+ WVVS R+ A + AQA RL +V+A E+D Sbjct: 456 TNAHVILEEAPTPVEASYSTADQQRLSVVPWVVSGRSTAALMAQASRLAFYVQADPEVDP 515 Query: 575 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFP 634 DVG +L RS+FEHRAVVVG R++L+AGLA + G G GVA G A P GKTV VFP Sbjct: 516 VDVGCALAA-RSVFEHRAVVVGESREQLIAGLAGLAVGESGAGVAIGQAAPLGKTVVVFP 574 Query: 635 GQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPA 694 GQGAQ +GMGRELC+ P ELDRH+ PLR+VVWGADA LL++TEFAQPA Sbjct: 575 GQGAQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGLLDSTEFAQPA 634 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAVEVAL+ +L+ WG++P VMGHS+GEL+AA+V+G RGRLMQ++P Sbjct: 635 LFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGRLMQSMPA 694 Query: 755 GGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLA 814 GG M+AV A E E+ LLGE V +AA+N P SVV+SG + AVS + D+ AAQGRRV +LA Sbjct: 695 GGTMWAVAASEDEVVSLLGEGVGIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLA 754 Query: 815 VSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAV 874 VSHAFHS LMEPMLE+F VA +V +P I ++SNVTG+L D+GS YW H+ AV Sbjct: 755 VSHAFHSPLMEPMLEEFVRVAAQVEVRKPQIGLVSNVTGELAGPDFGSPQYWGEHVSRAV 814 Query: 875 RFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXX 934 RF DS + GAT F+E GP+ GL IE+SLA V V + KDRPE Sbjct: 815 RFVDSARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAVVVSMMGKDRPELASVLGAAG 874 Query: 935 XXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 +W +V AG +RV LPTYAF RFW Sbjct: 875 QLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFW 910 Score = 84.0 bits (206), Expect = 3e-13 Identities = 43/98 (43%), Positives = 58/98 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RLQGL+ Q ++ +VC AAVLGR +D F D G SL+AVELRNRLK+ Sbjct: 1990 RLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSA 2049 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPE 2119 TG+TL T FD+PTPT +A+++ + P + E Sbjct: 2050 TGLTLPPTVIFDHPTPTAVAEYVAQQMLKSRPAESGDE 2087 Score = 82.4 bits (202), Expect = 7e-13 Identities = 41/87 (47%), Positives = 55/87 (63%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RLQGL+ Q ++ +VC AAVLGR +D F D G SL+AVELRNRLK+ Sbjct: 1990 RLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSA 2049 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL 1096 TG+TL T FD+PTPT +A+++ + Sbjct: 2050 TGLTLPPTVIFDHPTPTAVAEYVAQQM 2076 >tr|B8ZTY8|B8ZTY8_MYCLB Tax_Id=561304 SubName: Full=Putative polyketide synthase;[Mycobacterium leprae] Length = 2103 Score = 1032 bits (2668), Expect = 0.0 Identities = 532/874 (60%), Positives = 634/874 (72%), Gaps = 6/874 (0%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EP+A+VG+GCR+PGGV SP +LW +V+ DV+ EFP DRGWD++ LFDPDPDA GK Sbjct: 39 RATEPVAVVGIGCRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGK 98 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 TYTR G F+ D A FD GFFGI+P E LAMDPQQRL+LE SWEALE AGIDP +LRGS+T Sbjct: 99 TYTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSAT 158 Query: 1233 GVFVGIYGDGYGL-GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 GVF GI+ YG T Q Y TG SVASGR+SY LGL GPA+SVDTACSSSLVA+ Sbjct: 159 GVFTGIFAPSYGSRDTGGLQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTACSSSLVAI 218 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 H A +SLR+GECDLALAGG TV+ PSIF+GFSRQRGLA DGRCKAFA AADGTG+ EGA Sbjct: 219 HWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFARAADGTGWGEGA 278 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 G++VL+RLSDA+R G VLA++ GSAVNQDGASNGLTAP+G AQQRVI AAL++AG++ A Sbjct: 279 GVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSA 338 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 DVDVVEAHGT T LGDPIEAQALLATYG+ D PLW+GSIKSNMGH+QAAAGVAGVIK Sbjct: 339 DVDVVEAHGTATTLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAGVAGVIK 398 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV+AMRH ++PATLH+D+PS VDW+ G V +LTEAR+W +V GRPRRAGVSSFG+SGTN Sbjct: 399 MVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDW-SVEGRPRRAGVSSFGISGTN 457 Query: 1532 AHXXXXXXXXXXXXXXXXXGP---GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 1588 AH V+ WVVS R+ A + AQA RL +V+A E+D D Sbjct: 458 AHVILEEAPTPVEASYSTADQQRLSVVPWVVSGRSTAALMAQASRLAFYVQADPEVDPVD 517 Query: 1589 VGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQ 1648 VG +L RS+FEHRAVVVG R++L+AGLA + G G GVA G A P GKTV VFPGQ Sbjct: 518 VGCAL-AARSVFEHRAVVVGESREQLIAGLAGLAVGESGAGVAIGQAAPLGKTVVVFPGQ 576 Query: 1649 GAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALF 1708 GAQ +GMGRELC+ P ELDRH+ PLR+VVWGADA LL++TEFAQPALF Sbjct: 577 GAQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGLLDSTEFAQPALF 636 Query: 1709 AVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGG 1768 AVEVAL+ +L+ WG++P VMGHS+GEL+AA+V+G RGRLMQ++P GG Sbjct: 637 AVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGRLMQSMPAGG 696 Query: 1769 VMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVS 1828 M+AV A E E+ LLGE V +AA+N P SVV+SG + AVS + D+ AAQGRRV +LAVS Sbjct: 697 TMWAVAASEDEVVSLLGEGVGIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVS 756 Query: 1829 HAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRF 1888 HAFHS LMEPMLE+F VA +V +P I ++SNVTG+L D+GS YW H+ AVRF Sbjct: 757 HAFHSPLMEPMLEEFVRVAAQVEVRKPQIGLVSNVTGELAGPDFGSPQYWGEHVSRAVRF 816 Query: 1889 ADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXX 1948 DS + GAT F+E GP+ GL IE+SLA V V + KDRPE Sbjct: 817 VDSARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAVVVSMMGKDRPELASVLGAAGQL 876 Query: 1949 XXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 +W +V AG +RV LPTYAF RFW Sbjct: 877 FATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFW 910 Score = 781 bits (2016), Expect = 0.0 Identities = 432/876 (49%), Positives = 552/876 (63%), Gaps = 17/876 (1%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE------ 158 EP+AV+G+ CRF G V LWD ++E + ++E+P R D L D Sbjct: 42 EPVAVVGIGCRFPGGVDSPDRLWDVVSECRDVVSEFPTDR--GWDVDGLFDPDPDAEGKT 99 Query: 159 -TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTG 217 T +G FL+D GFD FF I P E MDPQQRL+LE SW ALE+AGI P +L+ S TG Sbjct: 100 YTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATG 159 Query: 218 VFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLV 277 VF G+ + Y GG + + TG + S+ + R+SY L + GP++ +DTACSSSLV Sbjct: 160 VFTGIFAPSYGSR-DTGGLQG--YGLTGTAVSVASGRVSYVLGLEGPAVSVDTACSSSLV 216 Query: 278 AAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGE 337 A H A SL SGECDLA+ G V+ P ++ GF ++ G C+AF ADG GE Sbjct: 217 AIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFARAADGTGWGE 276 Query: 338 GCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADID 397 G GVVVLERLSDA+R G TVLAV+ GSAVNQDG SNG+ APN AQ V+ +A A + Sbjct: 277 GAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLS 336 Query: 398 PAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGL 457 A++D VEAHGT T++GD IEA AL +G+GR A +PL +GSIK N+GH + AAG+AG+ Sbjct: 337 SADVDVVEAHGTATTLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAGVAGV 396 Query: 458 IKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGG 517 IK V ++ + + + P+P + + ++V+ E ++W +V GRPRRAGVSSFG G Sbjct: 397 IKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDW-SVEGRPRRAGVSSFGISG 455 Query: 518 TNAHXXXXXXXXXXXXXXXXXGP---GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 574 TNAH V+ WVVS R+ A + AQA RL +V+A E+D Sbjct: 456 TNAHVILEEAPTPVEASYSTADQQRLSVVPWVVSGRSTAALMAQASRLAFYVQADPEVDP 515 Query: 575 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFP 634 DVG +L RS+FEHRAVVVG R++L+AGLA + G G GVA G A P GKTV VFP Sbjct: 516 VDVGCALAA-RSVFEHRAVVVGESREQLIAGLAGLAVGESGAGVAIGQAAPLGKTVVVFP 574 Query: 635 GQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPA 694 GQGAQ +GMGRELC+ P ELDRH+ PLR+VVWGADA LL++TEFAQPA Sbjct: 575 GQGAQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGLLDSTEFAQPA 634 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAVEVAL+ +L+ WG++P VMGHS+GEL+AA+V+G RGRLMQ++P Sbjct: 635 LFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGRLMQSMPA 694 Query: 755 GGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLA 814 GG M+AV A E E+ LLGE V +AA+N P SVV+SG + AVS + D+ AAQGRRV +LA Sbjct: 695 GGTMWAVAASEDEVVSLLGEGVGIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLA 754 Query: 815 VSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAV 874 VSHAFHS LMEPMLE+F VA +V +P I ++SNVTG+L D+GS YW H+ AV Sbjct: 755 VSHAFHSPLMEPMLEEFVRVAAQVEVRKPQIGLVSNVTGELAGPDFGSPQYWGEHVSRAV 814 Query: 875 RFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXX 934 RF DS + GAT F+E GP+ GL IE+SLA V V + KDRPE Sbjct: 815 RFVDSARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAVVVSMMGKDRPELASVLGAAG 874 Query: 935 XXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 +W +V AG +RV LPTYAF RFW Sbjct: 875 QLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFW 910 Score = 84.0 bits (206), Expect = 3e-13 Identities = 43/98 (43%), Positives = 58/98 (59%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RLQGL+ Q ++ +VC AAVLGR +D F D G SL+AVELRNRLK+ Sbjct: 1990 RLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSA 2049 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPE 2119 TG+TL T FD+PTPT +A+++ + P + E Sbjct: 2050 TGLTLPPTVIFDHPTPTAVAEYVAQQMLKSRPAESGDE 2087 Score = 82.4 bits (202), Expect = 7e-13 Identities = 41/87 (47%), Positives = 55/87 (63%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RLQGL+ Q ++ +VC AAVLGR +D F D G SL+AVELRNRLK+ Sbjct: 1990 RLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSA 2049 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL 1096 TG+TL T FD+PTPT +A+++ + Sbjct: 2050 TGLTLPPTVIFDHPTPTAVAEYVAQQM 2076 >tr|B2HIL7|B2HIL7_MYCMM Tax_Id=216594 (pks15/1)SubName: Full=Polyketide synthase Pks15/1;[Mycobacterium marinum] Length = 2104 Score = 1027 bits (2655), Expect = 0.0 Identities = 536/878 (61%), Positives = 623/878 (70%), Gaps = 10/878 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EP+A+VG+GCR+PGG P LW LV+ G D + EFP DRGWD E LFDPDPDA GK Sbjct: 39 RATEPVAVVGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAEGK 98 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 TYTR G FV + +FD GFFGI P E LAMDPQQRL+LE SWEALE AGIDP +LRGSST Sbjct: 99 TYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHAGIDPMSLRGSST 158 Query: 1233 GVFVGIYGDGYG-LGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 GVF GI+ YG Q Y TG SVASGR++Y LGL GPA+SVDTACSSSLVA+ Sbjct: 159 GVFTGIFAPSYGGKDVGALQGYGLTGSPVSVASGRVAYVLGLEGPALSVDTACSSSLVAI 218 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 H A SLR+GECD+ALAGG TV+ PSIF+GFSRQRGLA DGRCKAFA AADGTG+ EGA Sbjct: 219 HWAMASLRSGECDMALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGA 278 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 G+LVL+RLSDA+R G VLA++ GSA+NQDGASNGLTAP+G AQQRVI AAL++ G+T A Sbjct: 279 GVLVLERLSDAQRNGHNVLAVVRGSAINQDGASNGLTAPNGLAQQRVIQAALANCGLTSA 338 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 DVDVVEAHGT T LGDPIEA+ALLATYG+ D PLW+GSIKSNMGH+QAAAGVAGVIK Sbjct: 339 DVDVVEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAGVAGVIK 398 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV+AMRH L+PA+LH+D+PS VDW G V +L EAR+WP GRPRRAGVSSFG+SGTN Sbjct: 399 MVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AGRPRRAGVSSFGISGTN 457 Query: 1532 AHXXXXXXXXXXXXXXXXXGPG-----VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 1586 AH G V+ WV+SAR+A + AQAGRLL V+A + + Sbjct: 458 AHVILEEAPAPEAVPDSESNKGEPSLPVVPWVISARSAEALTAQAGRLLAHVQADPQSNP 517 Query: 1587 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFP 1646 D+G+SL RS FEHRAVVVGA R +LL GLA + +G PG GV +G A GKT VFP Sbjct: 518 VDIGFSL-AGRSAFEHRAVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFP 576 Query: 1647 GQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPA 1706 GQG+Q +GM REL P ELDRHL PLREV+WG+DA LL++TEFAQPA Sbjct: 577 GQGSQRIGMARELHDQLPVFAEAFDAVADELDRHLRIPLREVMWGSDAALLDSTEFAQPA 636 Query: 1707 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 1766 LFAVEVAL+ L+ WG++P VMGHSVGELSAA+V+G RGRLMQALP Sbjct: 637 LFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVAGVLTLADAAMLVVARGRLMQALPA 696 Query: 1767 GGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLA 1826 GG M AV A E E+ P L + V +AA+N P SVV+SGA AV+ + D+ A QGRRV RLA Sbjct: 697 GGAMVAVAAAEDEVLPSLTDGVGIAAINAPKSVVISGAEAAVTAISDQFAQQGRRVHRLA 756 Query: 1827 VSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED--YGSADYWVRHIRE 1884 VSHAFHS LMEPMLE+F +A +V A P I ++SNVTG+L + D +GSA YWV H+R Sbjct: 757 VSHAFHSPLMEPMLEEFARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRR 816 Query: 1885 AVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXX 1944 AVRFADS H+ G T FVEVGP GLT IE+SLA V V L KDRPE Sbjct: 817 AVRFADSARQLHTLGVTHFVEVGPGSGLTGSIEQSLAPAEAVVVSMLGKDRPEVASVLTA 876 Query: 1945 XXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 DW +V AG G RV LPTYAF RFW Sbjct: 877 FGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFW 914 Score = 786 bits (2031), Expect = 0.0 Identities = 436/881 (49%), Positives = 547/881 (62%), Gaps = 23/881 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE-----T 159 EP+AV+G+ CRF G G LWD +++ + A+TE+P R + D T Sbjct: 42 EPVAVVGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAEGKTYT 101 Query: 160 IYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVF 219 +G F+E+ FD FF IPP E MDPQQRL+LE SW ALEHAGI P +L+ S TGVF Sbjct: 102 RWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHAGIDPMSLRGSSTGVF 161 Query: 220 VGVSSTDYVRLLFPGGRKPTIWDN---TGGSSSIIANRLSYFLDVNGPSLVIDTACSSSL 276 G+ + Y GG+ TG S+ + R++Y L + GP+L +DTACSSSL Sbjct: 162 TGIFAPSY------GGKDVGALQGYGLTGSPVSVASGRVAYVLGLEGPALSVDTACSSSL 215 Query: 277 VAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRG 336 VA H A SL SGECD+A+ G V+ P ++ GF ++ G C+AF A ADG G Sbjct: 216 VAIHWAMASLRSGECDMALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWG 275 Query: 337 EGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADI 396 EG GV+VLERLSDA+R G VLAV+ GSA+NQDG SNG+ APN AQ V+ +A + Sbjct: 276 EGAGVLVLERLSDAQRNGHNVLAVVRGSAINQDGASNGLTAPNGLAQQRVIQAALANCGL 335 Query: 397 DPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAG 456 A++D VEAHGT T++GD IEA AL +G+GR +PL +GSIK N+GH + AAG+AG Sbjct: 336 TSADVDVVEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAGVAG 395 Query: 457 LIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFG 516 +IK V ++ G + S + P+ + + ++V+ E ++WP GRPRRAGVSSFG Sbjct: 396 VIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPDA-GRPRRAGVSSFGIS 454 Query: 517 GTNAHXXXXXXXXXXXXXXXXXGPG-----VLAWVVSARTAAGVGAQAGRLLEFVRAGRE 571 GTNAH G V+ WV+SAR+A + AQAGRLL V+A + Sbjct: 455 GTNAHVILEEAPAPEAVPDSESNKGEPSLPVVPWVISARSAEALTAQAGRLLAHVQADPQ 514 Query: 572 LDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVF 631 + D+G+SL RS FEHRAVVVGA R +LL GLA + +G PG GV +G A GKT Sbjct: 515 SNPVDIGFSLAG-RSAFEHRAVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAV 573 Query: 632 VFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFA 691 VFPGQG+Q +GM REL P ELDRHL PLREV+WG+DA LL++TEFA Sbjct: 574 VFPGQGSQRIGMARELHDQLPVFAEAFDAVADELDRHLRIPLREVMWGSDAALLDSTEFA 633 Query: 692 QPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA 751 QPALFAVEVAL+ L+ WG++P VMGHSVGELSAA+V+G RGRLMQA Sbjct: 634 QPALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVAGVLTLADAAMLVVARGRLMQA 693 Query: 752 LPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 LP GG M AV A E E+ P L + V +AA+N P SVV+SGA AV+ + D+ A QGRRV Sbjct: 694 LPAGGAMVAVAAAEDEVLPSLTDGVGIAAINAPKSVVISGAEAAVTAISDQFAQQGRRVH 753 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED--YGSADYWVRH 869 RLAVSHAFHS LMEPMLE+F +A +V A P I ++SNVTG+L + D +GSA YWV H Sbjct: 754 RLAVSHAFHSPLMEPMLEEFARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEH 813 Query: 870 IREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXX 929 +R AVRFADS H+ G T FVEVGP GLT IE+SLA V V L KDRPE Sbjct: 814 VRRAVRFADSARQLHTLGVTHFVEVGPGSGLTGSIEQSLAPAEAVVVSMLGKDRPEVASV 873 Query: 930 XXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 DW +V AG G RV LPTYAF RFW Sbjct: 874 LTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFW 914 Score = 88.2 bits (217), Expect = 1e-14 Identities = 46/98 (46%), Positives = 60/98 (61%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GLS E+Q A++ +VC AAVLGR +D F D G SL+AVELRNRLK+ Sbjct: 1993 RLNGLSAGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNRLKSA 2052 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPE 2119 TG+TL T FD+PTPT +A+++ + T A E Sbjct: 2053 TGLTLPPTVIFDHPTPTAIAEYVGRQIPDSQATQAEEE 2090 Score = 87.0 bits (214), Expect = 3e-14 Identities = 43/83 (51%), Positives = 56/83 (67%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GLS E+Q A++ +VC AAVLGR +D F D G SL+AVELRNRLK+ Sbjct: 1993 RLNGLSAGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNRLKSA 2052 Query: 1070 TGVTLSATTAFDYPTPTQLADHL 1092 TG+TL T FD+PTPT +A+++ Sbjct: 2053 TGLTLPPTVIFDHPTPTAIAEYV 2075 >tr|D1GLV7|D1GLV7_9ACTO Tax_Id=47763 (slgA3)SubName: Full=Polyketide synthase type I;[Streptomyces lydicus] Length = 3447 Score = 1023 bits (2645), Expect = 0.0 Identities = 562/1003 (56%), Positives = 657/1003 (65%), Gaps = 31/1003 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL+ L + E+Q A L +VCE TA +LG G ++ A +AF++ G SL+A+ELRNRL Sbjct: 1723 RLRALPEDERQEAGLRLVCEQTAEILGYAGPDEVPAERAFNELGFDSLTALELRNRLTAS 1782 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRV--------RIDEPIAIV 1121 TG+ L AT FD+PTP LA HL + +A A V D+P+ IV Sbjct: 1783 TGLQLPATLVFDHPTPEALARHLTGEVTGAGGTASAPVPTPTVPPACSLSEADDDPVVIV 1842 Query: 1122 GMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFV 1181 M CRYPGGV +P QLWQLVASG DVI +FP DRGW E L+ PDPD G TY+ GGF+ Sbjct: 1843 SMACRYPGGVRTPEQLWQLVASGSDVISDFPADRGWHTEELYHPDPDHPGTTYSCEGGFL 1902 Query: 1182 SDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGD 1241 D DFD GFFGISP EALAMDPQQRLLLETSWEA+E AG+DP+ALRGS TGVF G+ Sbjct: 1903 YDAGDFDAGFFGISPREALAMDPQQRLLLETSWEAVERAGLDPRALRGSRTGVFTGVMYH 1962 Query: 1242 GYGLGTSQA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANS 1297 YG G + + G S+ASGR+SY LGL GPA++VDTACSSSLVALHLAA + Sbjct: 1963 DYGSGLDDVPEDVEAFLGNGSAGSIASGRVSYALGLEGPAVTVDTACSSSLVALHLAAQA 2022 Query: 1298 LRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQ 1357 LR+GEC LALAGG+TV+ATP F+GFSRQRGLA DGRCKAFAD ADGTG+ EG G+L+L+ Sbjct: 2023 LRSGECTLALAGGATVMATPGTFVGFSRQRGLAADGRCKAFADGADGTGWGEGVGVLLLE 2082 Query: 1358 RLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVE 1417 RLSDARR G PVLA++ GSAVNQDGASNGLTAP+GPAQQRVI AL A + ADVD VE Sbjct: 2083 RLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALDHARLGPADVDAVE 2142 Query: 1418 AHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMR 1477 HGTGT LGDPIEAQALLATYG+ PLWLGS+KSNMGH+QAAAGV GV+KMV A+R Sbjct: 2143 GHGTGTTLGDPIEAQALLATYGQRPEDQHPLWLGSLKSNMGHTQAAAGVGGVMKMVLALR 2202 Query: 1478 HQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXX 1537 H +LP TLH+D+PS HVDWS G V LLTE WP GRPRRAGVSSFG+SGTNAH Sbjct: 2203 HGVLPRTLHVDRPSRHVDWSAGAVSLLTEQVPWPE-TGRPRRAGVSSFGISGTNAHVILE 2261 Query: 1538 XXXXXXXXXXXXXG-----PG----VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 1588 PG VL WV+SART A + QA L E + E A D Sbjct: 2262 QPAPVAMGAGSDTSDVPNQPGGPAPVLPWVLSARTPAALREQAAALGELLTERPETAAAD 2321 Query: 1589 VGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQ 1648 +G+SL TTR+ FEHRA VV R LA LA + G G G A G +T +F GQ Sbjct: 2322 LGFSLATTRTAFEHRAAVVAGDRAGALAALASLARGESAPGALRGTATAGARTAVLFSGQ 2381 Query: 1649 GAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA----DAELLNTTEFAQ 1704 G+Q GMG EL A +P LD LARPLREVV+ A DA LL+ TE+AQ Sbjct: 2382 GSQRAGMGTELYASFPVYARAFDEVCAHLDPRLARPLREVVFAAPESPDAALLDRTEYAQ 2441 Query: 1705 PALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQAL 1764 PALFAVEVAL+RL ESWG+RP V GHS+GEL+AAHV+G RG +MQAL Sbjct: 2442 PALFAVEVALFRLWESWGLRPDAVAGHSIGELAAAHVAGVFDLADAARLVTARGGVMQAL 2501 Query: 1765 PGGGVMYAVQAGEQELRPLLG---EQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRR 1821 PGGG M ++QA E E+ PLL +V+VAAVNGP SVV+SG AV+ V A GRR Sbjct: 2502 PGGGAMVSLQAAEDEVLPLLAGREREVAVAAVNGPASVVVSGTEGAVADVAAHFEALGRR 2561 Query: 1822 VRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVA-EDYGSADYWVR 1880 RRL VSHAFHS LM+P L+ FR VA EV P IP++S+VTG E +YWVR Sbjct: 2562 TRRLRVSHAFHSPLMDPALDAFRQVAREVTYHAPRIPLVSDVTGDTATDEQLADPEYWVR 2621 Query: 1881 HIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFX 1940 H REAVRFAD V G T FVEVGP LT++ ES VAV +LR+DRPE Sbjct: 2622 HAREAVRFADQVRTLAGRGVTTFVEVGPDAVLTAMARES-RSADAVAVASLRRDRPECRA 2680 Query: 1941 XXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DW V A G +RV LPTYAF +R+WL Sbjct: 2681 VATALAELHVGGVRVDWQGVFADTGARRVELPTYAFQRDRYWL 2723 Score = 806 bits (2081), Expect = 0.0 Identities = 457/909 (50%), Positives = 560/909 (61%), Gaps = 82/909 (9%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EP+AIVGM CR+PGGV +P LW+LVA G D + EFP DRGW+ + L Sbjct: 36 RSHEPLAIVGMSCRFPGGVRTPEDLWRLVAGGEDAVSEFPADRGWNTDVL---------- 85 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 GGFV D ADFD GFFGISP EALAMDPQQRLLLETSWEA+E AG+DP+ALRGS T Sbjct: 86 --RGEGGFVHDAADFDAGFFGISPREALAMDPQQRLLLETSWEAVERAGLDPRALRGSRT 143 Query: 1233 GVFVGI----YGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSL 1288 GVF G+ Y D + Y G S+ASGR+SY LGL GPA++VDTACSSSL Sbjct: 144 GVFTGVMYHDYADLVLRSPDAVEGYVYNGSAGSIASGRVSYVLGLEGPAVTVDTACSSSL 203 Query: 1289 VALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRG--LATDGRCKAFADAADGTG 1346 VALHLAA +LR+GEC LALAGG+ V++TP +F F+R +G LA+DGRCKAFAD+ADGT Sbjct: 204 VALHLAAQALRSGECTLALAGGAAVMSTPVLFDEFARGQGIGLASDGRCKAFADSADGTN 263 Query: 1347 FSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDA 1406 SEG G+L+L+RLSDARR G PVLA++A A Sbjct: 264 LSEGVGVLLLERLSDARRNGHPVLAVVA------------------------------QA 293 Query: 1407 GITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGV 1466 +T ADVD VEAHGTGT LGDPIEAQALL TYG+ PLWLGS+KSN+GH+QAAAGV Sbjct: 294 RLTCADVDAVEAHGTGTALGDPIEAQALLETYGQQREGQQPLWLGSLKSNIGHTQAAAGV 353 Query: 1467 AGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFG 1526 GV+KMV A+RH +LP TLH+D+PS HVDWS G V LLTE WP GRPRRAGVSSFG Sbjct: 354 GGVMKMVLALRHGVLPRTLHVDRPSRHVDWSAGAVSLLTEQVPWPE-TGRPRRAGVSSFG 412 Query: 1527 VSGTNAHXXXXXXXXXXXXXXXXXG----------------PGVLAWVVSARTAAGVGAQ 1570 VSGTNAH P + WV+SAR+ A + AQ Sbjct: 413 VSGTNAHVIVEQAPDDQEPAERAASAEPEAPLSDTDADVARPLPVPWVLSARSGAALCAQ 472 Query: 1571 AGRLLEFVRAGRELDAGDV-GYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVG 1629 A RL + A E D+ V +L TTR+ FEHRAV+ G L A L + EGR Sbjct: 473 AARLRAHLAAAHETDSPRVTALALATTRTAFEHRAVLHSGGPGGLSAALDALAEGRTAPS 532 Query: 1630 VASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVV 1689 V G G+T F+F GQG+Q+ GMGREL AG P LD HL RPL +V+ Sbjct: 533 VVRGPGRREGRTAFLFTGQGSQYAGMGRELYAGSPAFAAALDEVTRHLDPHLERPLLDVL 592 Query: 1690 W----GADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXX 1745 + DA ++ T + Q LFAVEVAL+RL+E WG+RP ++GHS+GEL+AAHV+G Sbjct: 593 FAEPDSPDAAAIDRTRYTQAGLFAVEVALFRLVEGWGLRPDALLGHSIGELAAAHVAGVF 652 Query: 1746 XXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLG---EQVSVAAVNGPGSVVLS 1802 RGRLMQ LP GG M +V+AGE ++RPLL ++V +AAVNGP SVV+S Sbjct: 653 DLADACRLVAARGRLMQDLPTGGAMVSVRAGEDDVRPLLAGQEDRVGIAAVNGPRSVVVS 712 Query: 1803 GAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISN 1862 G +AV V LA +G R +RL VSHAFHS M+PML FR +A+ V P IPVISN Sbjct: 713 GDEDAVLAVAAELAGRGHRTKRLNVSHAFHSPRMDPMLRDFRRLAETVDFHPPRIPVISN 772 Query: 1863 VTGQ-LVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLA 1921 VTG+ AE+ + +YWV+HIR+AVRF D + G ++E+GP G L ++ +E+L Sbjct: 773 VTGRTATAEELCAPEYWVQHIRQAVRFGDGIRALRDLGVGTYLELGPGGVLCAMGQEALG 832 Query: 1922 QVSVVA------VPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGG--QRVGLPT 1973 + TLR+ RPEP DWA+ L G G +RV LPT Sbjct: 833 DGPAASAGDSPFAATLRRGRPEPESVLEAVAAAFVRGTDVDWAAYLGGGDGRRRRVDLPT 892 Query: 1974 YAFAHERFW 1982 YAF +R+W Sbjct: 893 YAFQRQRYW 901 Score = 720 bits (1859), Expect = 0.0 Identities = 434/973 (44%), Positives = 554/973 (56%), Gaps = 34/973 (3%) Query: 29 EVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLG---GDGS 85 EV + +LG S+ L + L+ G+ +P V+D+P+ + + + G G G Sbjct: 1755 EVPAERAFNELGFDSLTALELRNRLTASTGLQLPATLVFDHPTPEALARHLTGEVTGAGG 1814 Query: 86 QRSADSDT-----GCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEY 140 SA T C++ + ++P+ ++ MACR+ G V LW +A I+++ Sbjct: 1815 TASAPVPTPTVPPACSL--SEADDDPVVIVSMACRYPGGVRTPEQLWQLVASGSDVISDF 1872 Query: 141 PARRLGAAAADWLGDEQE--TIYGC---FLEDVEGFDNKFFDIPPDEAALMDPQQRLLLE 195 PA R + D T Y C FL D FD FF I P EA MDPQQRLLLE Sbjct: 1873 PADRGWHTEELYHPDPDHPGTTYSCEGGFLYDAGDFDAGFFGISPREALAMDPQQRLLLE 1932 Query: 196 TSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRL 255 TSW A+E AG+ P+ L+ S TGVF GV DY L + G + SI + R+ Sbjct: 1933 TSWEAVERAGLDPRALRGSRTGVFTGVMYHDYGSGLDDVPEDVEAFLGNGSAGSIASGRV 1992 Query: 256 SYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAG 315 SY L + GP++ +DTACSSSLVA HLA ++L SGEC LA+ G V+ +P + GF Sbjct: 1993 SYALGLEGPAVTVDTACSSSLVALHLAAQALRSGECTLALAGGATVMATPGTFVGFSRQR 2052 Query: 316 VVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGI 375 ++ G C+AF ADG GEG GV++LERLSDARR G VLAV+ GSAVNQDG SNG+ Sbjct: 2053 GLAADGRCKAFADGADGTGWGEGVGVLLLERLSDARRNGHPVLAVVRGSAVNQDGASNGL 2112 Query: 376 MAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKP 435 APN AQ V+ A A + PA++D VE HGTGT++GD IEA AL +G+ + P Sbjct: 2113 TAPNGPAQQRVIRQALDHARLGPADVDAVEGHGTGTTLGDPIEAQALLATYGQRPEDQHP 2172 Query: 436 LMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEF 495 L +GS+K N+GH + AAG+ G++K VL L+ G L + + P+ ++ ++ ++++ E Sbjct: 2173 LWLGSLKSNMGHTQAAAGVGGVMKMVLALRHGVLPRTLHVDRPSRHVDWSAGAVSLLTEQ 2232 Query: 496 QEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXG-----PG----VLAWV 546 WP GRPRRAGVSSFG GTNAH PG VL WV Sbjct: 2233 VPWPE-TGRPRRAGVSSFGISGTNAHVILEQPAPVAMGAGSDTSDVPNQPGGPAPVLPWV 2291 Query: 547 VSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGL 606 +SART A + QA L E + E A D+G+SL TTR+ FEHRA VV R LA L Sbjct: 2292 LSARTPAALREQAAALGELLTERPETAAADLGFSLATTRTAFEHRAAVVAGDRAGALAAL 2351 Query: 607 AEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELD 666 A + G G G A G +T +F GQG+Q GMG EL A +P LD Sbjct: 2352 ASLARGESAPGALRGTATAGARTAVLFSGQGSQRAGMGTELYASFPVYARAFDEVCAHLD 2411 Query: 667 RHLARPLREVVWGA----DAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVG 722 LARPLREVV+ A DA LL+ TE+AQPALFAVEVAL+RL ESWG+RP V GHS+G Sbjct: 2412 PRLARPLREVVFAAPESPDAALLDRTEYAQPALFAVEVALFRLWESWGLRPDAVAGHSIG 2471 Query: 723 ELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLG---EQVSVA 779 EL+AAHV+G RG +MQALPGGG M ++QA E E+ PLL +V+VA Sbjct: 2472 ELAAAHVAGVFDLADAARLVTARGGVMQALPGGGAMVSLQAAEDEVLPLLAGREREVAVA 2531 Query: 780 AVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVY 839 AVNGP SVV+SG AV+ V A GRR RRL VSHAFHS LM+P L+ FR VA EV Sbjct: 2532 AVNGPASVVVSGTEGAVADVAAHFEALGRRTRRLRVSHAFHSPLMDPALDAFRQVAREVT 2591 Query: 840 AGRPAIPVISNVTGQLVA-EDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAG 898 P IP++S+VTG E +YWVRH REAVRFAD V G T FVEVGP Sbjct: 2592 YHAPRIPLVSDVTGDTATDEQLADPEYWVRHAREAVRFADQVRTLAGRGVTTFVEVGPDA 2651 Query: 899 GLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVG 958 LT++ ES VAV +LR+DRPE DW V A G +RV Sbjct: 2652 VLTAMARES-RSADAVAVASLRRDRPECRAVATALAELHVGGVRVDWQGVFADTGARRVE 2710 Query: 959 LPTYAFAHERFWL 971 LPTYAF +R+WL Sbjct: 2711 LPTYAFQRDRYWL 2723 Score = 625 bits (1613), Expect = e-176 Identities = 383/904 (42%), Positives = 508/904 (56%), Gaps = 75/904 (8%) Query: 103 TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQETIYG 162 ++EP+A++GM+CRF G V LW +A + A++E+PA R D L E G Sbjct: 37 SHEPLAIVGMSCRFPGGVRTPEDLWRLVAGGEDAVSEFPADR--GWNTDVLRGE-----G 89 Query: 163 CFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGV 222 F+ D FD FF I P EA MDPQQRLLLETSW A+E AG+ P+ L+ S TGVF GV Sbjct: 90 GFVHDAADFDAGFFGISPREALAMDPQQRLLLETSWEAVERAGLDPRALRGSRTGVFTGV 149 Query: 223 SSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLA 282 DY L+ + G + SI + R+SY L + GP++ +DTACSSSLVA HLA Sbjct: 150 MYHDYADLVLRSPDAVEGYVYNGSAGSIASGRVSYVLGLEGPAVTVDTACSSSLVALHLA 209 Query: 283 RKSLASGECDLAVVAGTNVLISPEVWRGF---QEAGVVSPTGSCRAFDARADGMVRGEGC 339 ++L SGEC LA+ G V+ +P ++ F Q G+ S G C+AF ADG EG Sbjct: 210 AQALRSGECTLALAGGAAVMSTPVLFDEFARGQGIGLASD-GRCKAFADSADGTNLSEGV 268 Query: 340 GVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPA 399 GV++LERLSDARR G VLAV V + CAD+D Sbjct: 269 GVLLLERLSDARRNGHPVLAV-------------------------VAQARLTCADVDA- 302 Query: 400 EIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIK 459 VEAHGTGT++GD IEA AL + +G+ R+ +PL +GS+K NIGH + AAG+ G++K Sbjct: 303 ----VEAHGTGTALGDPIEAQALLETYGQQREGQQPLWLGSLKSNIGHTQAAAGVGGVMK 358 Query: 460 TVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTN 519 VL L+ G L + + P+ ++ ++ ++++ E WP GRPRRAGVSSFG GTN Sbjct: 359 MVLALRHGVLPRTLHVDRPSRHVDWSAGAVSLLTEQVPWPET-GRPRRAGVSSFGVSGTN 417 Query: 520 AHXXXXXXXXXXXXXXXXXG----------------PGVLAWVVSARTAAGVGAQAGRLL 563 AH P + WV+SAR+ A + AQA RL Sbjct: 418 AHVIVEQAPDDQEPAERAASAEPEAPLSDTDADVARPLPVPWVLSARSGAALCAQAARLR 477 Query: 564 EFVRAGRELDAGDV-GYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGV 622 + A E D+ V +L TTR+ FEHRAV+ G L A L + EGR V G Sbjct: 478 AHLAAAHETDSPRVTALALATTRTAFEHRAVLHSGGPGGLSAALDALAEGRTAPSVVRGP 537 Query: 623 AMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGA-- 680 G+T F+F GQG+Q+ GMGREL AG P LD HL RPL +V++ Sbjct: 538 GRREGRTAFLFTGQGSQYAGMGRELYAGSPAFAAALDEVTRHLDPHLERPLLDVLFAEPD 597 Query: 681 --DAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXX 738 DA ++ T + Q LFAVEVAL+RL+E WG+RP ++GHS+GEL+AAHV+G Sbjct: 598 SPDAAAIDRTRYTQAGLFAVEVALFRLVEGWGLRPDALLGHSIGELAAAHVAGVFDLADA 657 Query: 739 XXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLG---EQVSVAAVNGPGSVVLSGAREA 795 RGRLMQ LP GG M +V+AGE ++RPLL ++V +AAVNGP SVV+SG +A Sbjct: 658 CRLVAARGRLMQDLPTGGAMVSVRAGEDDVRPLLAGQEDRVGIAAVNGPRSVVVSGDEDA 717 Query: 796 VSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQ- 854 V V LA +G R +RL VSHAFHS M+PML FR +A+ V P IPVISNVTG+ Sbjct: 718 VLAVAAELAGRGHRTKRLNVSHAFHSPRMDPMLRDFRRLAETVDFHPPRIPVISNVTGRT 777 Query: 855 LVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVV 914 AE+ + +YWV+HIR+AVRF D + G ++E+GP G L ++ +E+L Sbjct: 778 ATAEELCAPEYWVQHIRQAVRFGDGIRALRDLGVGTYLELGPGGVLCAMGQEALGDGPAA 837 Query: 915 A------VPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGG--QRVGLPTYAFAH 966 + TLR+ RPEP DWA+ L G G +RV LPTYAF Sbjct: 838 SAGDSPFAATLRRGRPEPESVLEAVAAAFVRGTDVDWAAYLGGGDGRRRRVDLPTYAFQR 897 Query: 967 ERFW 970 +R+W Sbjct: 898 QRYW 901 Score = 85.5 bits (210), Expect = 9e-14 Identities = 61/158 (38%), Positives = 84/158 (53%), Gaps = 13/158 (8%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL+ L + E+Q A L +VCE TA +LG G ++ A +AF++ G SL+A+ELRNRL Sbjct: 1723 RLRALPEDERQEAGLRLVCEQTAEILGYAGPDEVPAERAFNELGFDSLTALELRNRLTAS 1782 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGR-DD 2140 TG+ L AT FD+PTP LA HL + T + P T C DD Sbjct: 1783 TGLQLPATLVFDHPTPEALARHLTGEVTGAGGTASAP------VPTPTVPPACSLSEADD 1836 Query: 2141 DGWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDV 2178 D IV++A + T P++ W+ L+A G SDV Sbjct: 1837 DPVVIVSMACRYPGGVRT--PEQLWQ---LVASG-SDV 1868 Score = 62.4 bits (150), Expect = 8e-07 Identities = 36/87 (41%), Positives = 48/87 (55%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL ++ A +L +V +A VLG + A F D G S++AVELRN+L Sbjct: 3353 RLAGLPADQRPALLLELVRARSATVLGHADPRSVGADDDFLDIGFASMTAVELRNQLVAD 3412 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL 1096 TGV L T +D PTP LA +LL + Sbjct: 3413 TGVELPPTLIYDCPTPAALATYLLEEV 3439 Score = 62.4 bits (150), Expect = 8e-07 Identities = 36/87 (41%), Positives = 48/87 (55%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL ++ A +L +V +A VLG + A F D G S++AVELRN+L Sbjct: 3353 RLAGLPADQRPALLLELVRARSATVLGHADPRSVGADDDFLDIGFASMTAVELRNQLVAD 3412 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TGV L T +D PTP LA +LL + Sbjct: 3413 TGVELPPTLIYDCPTPAALATYLLEEV 3439 >tr|B2HR36|B2HR36_MYCMM Tax_Id=216594 (pks8)SubName: Full=Polyketide synthase, Pks8;[Mycobacterium marinum] Length = 2114 Score = 1021 bits (2641), Expect = 0.0 Identities = 535/875 (61%), Positives = 621/875 (70%), Gaps = 6/875 (0%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 ++ EP+A+VGMGCRYPGG SP LW+++ G D + EFP DRGWDI+ +FDPDPDA GK Sbjct: 31 KLSEPVALVGMGCRYPGGADSPESLWEMLTQGRDAVSEFPSDRGWDIDAMFDPDPDARGK 90 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 TYTR GGF++D DFD GFFG+ P EALAMDPQQRL+LE SWEALE +GIDP LRGS+T Sbjct: 91 TYTRRGGFLADAGDFDAGFFGVGPNEALAMDPQQRLMLEVSWEALERSGIDPTTLRGSAT 150 Query: 1233 GVFVGIYGDGYGLGTS-QAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 GVFVG+ GYG + + Y TG SVASGR++Y LGL GPA+SVDTACSSSLVAL Sbjct: 151 GVFVGVIHAGYGGEVKGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSSLVAL 210 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 HLAA SLR+ ECDLAL GG TV+ATP+ F+ FSRQR LA DG CKA+A AADGT +SEGA Sbjct: 211 HLAAQSLRSRECDLALVGGVTVMATPAAFVEFSRQRALAADGLCKAYAGAADGTTWSEGA 270 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 G+LV++RL+DA+R G PVLA++ GSAVNQDGASNGLTAP+GP+QQRVI AAL+ A + A Sbjct: 271 GVLVVERLADAQRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALASARLGVA 330 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 DVDVVE HGTGT LGDPIEAQA+LATYG+D T PLWLGSIKSN+GH+ AAAGVAG+IK Sbjct: 331 DVDVVEGHGTGTVLGDPIEAQAILATYGQDRTE--PLWLGSIKSNIGHTSAAAGVAGLIK 388 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AM+H +LP TLH+D P+ HVDWS G V LLTE+R WP + GRPRRAGVSSFG+SGTN Sbjct: 389 MVLAMQHGVLPQTLHVDVPTPHVDWSAGAVSLLTESRPWPDL-GRPRRAGVSSFGISGTN 447 Query: 1532 AHXXXXXXXXXXXXXXXXX-GPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVG 1590 AH G + WV+SAR+A + QA RLL + +LD DVG Sbjct: 448 AHVILEQAPTAEHDLAEPDRGAPTVPWVLSARSAPALANQAQRLLSWAEEHPDLDPVDVG 507 Query: 1591 YSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGA 1650 +SL TRSLFEHRAVVVG R +L+ GLA VV G PG GV G A GKTVFVFPGQGA Sbjct: 508 WSLAATRSLFEHRAVVVGTDRTQLMDGLAGVVAGEPGAGVVVGRARSTGKTVFVFPGQGA 567 Query: 1651 QWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAV 1710 Q+LGMGR L + ELD HL PLR+V+WG D LL +TEFAQPALFAV Sbjct: 568 QYLGMGRVLYERFSAFSTAFDAAAAELDAHLRLPLRQVMWGTDEGLLESTEFAQPALFAV 627 Query: 1711 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 1770 EVAL LL G+ P LV+GHSVGE+SAAHV+G RGRLM L GG M Sbjct: 628 EVALAALLSQLGVVPDLVLGHSVGEISAAHVAGVLSLPDAARLVAARGRLMAGLAAGGAM 687 Query: 1771 YAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHA 1830 AV A EQE+ PLLG V+VAAVNGP SVV+SG AV VVDR+AA GRR RLAVSHA Sbjct: 688 VAVAASEQEVTPLLGSGVAVAAVNGPDSVVISGPEAAVGEVVDRIAALGRRTHRLAVSHA 747 Query: 1831 FHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFAD 1890 FHS LM+PML F V V A +P I ++SNVTGQL YGSA YWV H+R+ VRFAD Sbjct: 748 FHSELMDPMLPDFAEVLKGVSASQPRISLVSNVTGQLAEAGYGSAAYWVEHVRKPVRFAD 807 Query: 1891 SVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXX 1950 SV A S GA FVEVGP+GGLT+L+E+SL + AVP L KDRPE Sbjct: 808 SVALAESLGAAAFVEVGPSGGLTALVEQSLTR-ETPAVPLLIKDRPENDALLLGLGQLFA 866 Query: 1951 XXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLAD 1985 DW AG G QR LPTY F R+WL + Sbjct: 867 DGRALDWREAFAGLGAQRTDLPTYGFVRRRYWLKE 901 Score = 771 bits (1992), Expect = 0.0 Identities = 437/879 (49%), Positives = 541/879 (61%), Gaps = 19/879 (2%) Query: 104 NEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE----- 158 +EP+A++GM CR+ G LW+ L + + A++E+P+ R A + D Sbjct: 33 SEPVALVGMGCRYPGGADSPESLWEMLTQGRDAVSEFPSDRGWDIDAMFDPDPDARGKTY 92 Query: 159 TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGV 218 T G FL D FD FF + P+EA MDPQQRL+LE SW ALE +GI P TL+ S TGV Sbjct: 93 TRRGGFLADAGDFDAGFFGVGPNEALAMDPQQRLMLEVSWEALERSGIDPTTLRGSATGV 152 Query: 219 FVGVSSTDYVRLLFPGGRKPTIWDN---TGGSSSIIANRLSYFLDVNGPSLVIDTACSSS 275 FVGV Y GG + TG + S+ + R++Y L + GP++ +DTACSSS Sbjct: 153 FVGVIHAGY------GGEVKGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSS 206 Query: 276 LVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVR 335 LVA HLA +SL S ECDLA+V G V+ +P + F ++ G C+A+ ADG Sbjct: 207 LVALHLAAQSLRSRECDLALVGGVTVMATPAAFVEFSRQRALAADGLCKAYAGAADGTTW 266 Query: 336 GEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCAD 395 EG GV+V+ERL+DA+R G VLAV+ GSAVNQDG SNG+ APN +Q V+ +A A Sbjct: 267 SEGAGVLVVERLADAQRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALASAR 326 Query: 396 IDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIA 455 + A++D VE HGTGT +GD IEA A+ +G+ R +PL +GSIK NIGH AAG+A Sbjct: 327 LGVADVDVVEGHGTGTVLGDPIEAQAILATYGQDR--TEPLWLGSIKSNIGHTSAAAGVA 384 Query: 456 GLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGF 515 GLIK VL +Q G L + +VP P++ ++ ++++ E + WP + GRPRRAGVSSFG Sbjct: 385 GLIKMVLAMQHGVLPQTLHVDVPTPHVDWSAGAVSLLTESRPWPDL-GRPRRAGVSSFGI 443 Query: 516 GGTNAHXXXXXXXXXXXXXXXXX-GPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 574 GTNAH G + WV+SAR+A + QA RLL + +LD Sbjct: 444 SGTNAHVILEQAPTAEHDLAEPDRGAPTVPWVLSARSAPALANQAQRLLSWAEEHPDLDP 503 Query: 575 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFP 634 DVG+SL TRSLFEHRAVVVG R +L+ GLA VV G PG GV G A GKTVFVFP Sbjct: 504 VDVGWSLAATRSLFEHRAVVVGTDRTQLMDGLAGVVAGEPGAGVVVGRARSTGKTVFVFP 563 Query: 635 GQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPA 694 GQGAQ+LGMGR L + ELD HL PLR+V+WG D LL +TEFAQPA Sbjct: 564 GQGAQYLGMGRVLYERFSAFSTAFDAAAAELDAHLRLPLRQVMWGTDEGLLESTEFAQPA 623 Query: 695 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 754 LFAVEVAL LL G+ P LV+GHSVGE+SAAHV+G RGRLM L Sbjct: 624 LFAVEVALAALLSQLGVVPDLVLGHSVGEISAAHVAGVLSLPDAARLVAARGRLMAGLAA 683 Query: 755 GGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLA 814 GG M AV A EQE+ PLLG V+VAAVNGP SVV+SG AV VVDR+AA GRR RLA Sbjct: 684 GGAMVAVAASEQEVTPLLGSGVAVAAVNGPDSVVISGPEAAVGEVVDRIAALGRRTHRLA 743 Query: 815 VSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAV 874 VSHAFHS LM+PML F V V A +P I ++SNVTGQL YGSA YWV H+R+ V Sbjct: 744 VSHAFHSELMDPMLPDFAEVLKGVSASQPRISLVSNVTGQLAEAGYGSAAYWVEHVRKPV 803 Query: 875 RFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXX 934 RFADSV A S GA FVEVGP+GGLT+L+E+SL + AVP L KDRPE Sbjct: 804 RFADSVALAESLGAAAFVEVGPSGGLTALVEQSLTR-ETPAVPLLIKDRPENDALLLGLG 862 Query: 935 XXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLAD 973 DW AG G QR LPTY F R+WL + Sbjct: 863 QLFADGRALDWREAFAGLGAQRTDLPTYGFVRRRYWLKE 901 Score = 91.3 bits (225), Expect = 2e-15 Identities = 54/136 (39%), Positives = 79/136 (58%), Gaps = 7/136 (5%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL LS ++ ++ M+C + A VLG + + +DA + F D G SL+AVELRNRLK+ Sbjct: 1942 RLHTLSPEQRSRELVDMICTNAATVLG-NASVDIDANKPFQDLGFDSLTAVELRNRLKSS 2000 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 TG+TLS T FDYPTP LA+HL + L +P A + +R+ A D + D+ ++ Sbjct: 2001 TGLTLSPTLIFDYPTPAALAEHLSTQLSSLSPAAADEQPNRL-ARFDAVARELDSMINEP 2059 Query: 2142 GWQIVALAANGRERMT 2157 W A RER++ Sbjct: 2060 DW-----TAEDRERVS 2070 Score = 85.5 bits (210), Expect = 9e-14 Identities = 47/98 (47%), Positives = 64/98 (65%), Gaps = 4/98 (4%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL LS ++ ++ M+C + A VLG + + +DA + F D G SL+AVELRNRLK+ Sbjct: 1942 RLHTLSPEQRSRELVDMICTNAATVLG-NASVDIDANKPFQDLGFDSLTAVELRNRLKSS 2000 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAA 1107 TG+TLS T FDYPTP LA+HL + L + +PAAA Sbjct: 2001 TGLTLSPTLIFDYPTPAALAEHLSTQL---SSLSPAAA 2035 >tr|Q52V46|Q52V46_9ACTO Tax_Id=255848 SubName: Full=Polyketide synthase type I;[Streptomyces aizunensis] Length = 8147 Score = 1021 bits (2641), Expect = 0.0 Identities = 551/1003 (54%), Positives = 669/1003 (66%), Gaps = 37/1003 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L DAE++ +L +VC A VLG A +DA +AF + G SL+AVELRN LK Sbjct: 4889 RLSALPDAEREDMLLDLVCGRVAEVLGHTDARAVDADRAFKELGFDSLTAVELRNVLKAA 4948 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHH--------QNRSAPA---AAVRTRVRIDEPI 1118 TG+ LS T FDYPTP LA HLL+ L + R APA A T V ++PI Sbjct: 4949 TGLRLSPTLVFDYPTPVALARHLLAELAGTADDQDAVRGRKAPARPATAAVTSVTGEDPI 5008 Query: 1119 AIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHG 1178 IVGMGCR+PGGV SP LWQLVA+GGD I FP DRGW++E L+ PDPD G +YTR G Sbjct: 5009 VIVGMGCRFPGGVRSPEDLWQLVATGGDGITGFPSDRGWNVEALYHPDPDHAGTSYTREG 5068 Query: 1179 GFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGI 1238 GF+ D ADFDPGFFGISP EALAMDPQQRLLLETSWEA E AGIDP LRGS TGVF G+ Sbjct: 5069 GFLHDAADFDPGFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGV 5128 Query: 1239 ----YGDGYGLGTSQAQW------YADTGHITSVASGRISYCLGLAGPAISVDTACSSSL 1288 Y G G G S + Y TG+ S+ASGRI+Y GL GPA++VDTACSSSL Sbjct: 5129 MYHDYVTGIGDGGSAVELPEGVEGYLGTGNAGSIASGRIAYTFGLEGPAVTVDTACSSSL 5188 Query: 1289 VALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFS 1348 VALH A +LR+GEC +ALAGG V+ATP F+ FSRQRGL+ DGRCK+FA AADGTG++ Sbjct: 5189 VALHWAIQALRSGECTMALAGGVAVMATPETFVDFSRQRGLSADGRCKSFAAAADGTGWA 5248 Query: 1349 EGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGI 1408 EGAGML+++RLSDA R G PVLA++ GSA+NQDGASNGLTAP+GP+QQRVI AL+ A + Sbjct: 5249 EGAGMLLVERLSDAERNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIREALASADL 5308 Query: 1409 TGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAG 1468 + AD+D VEAHGTGTRLGDPIEAQALLATYGR+ PLWLGSIKSN+GH+QAAAGVAG Sbjct: 5309 SAADIDAVEAHGTGTRLGDPIEAQALLATYGREREAGRPLWLGSIKSNIGHTQAAAGVAG 5368 Query: 1469 VIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVS 1528 +IKMV AMRH +LP TLH+D+PS VDW G V LLT A WP GRPRRAGVSSFG+S Sbjct: 5369 IIKMVMAMRHGVLPQTLHVDEPSPQVDWEAGEVSLLTGAMPWPQ-TGRPRRAGVSSFGIS 5427 Query: 1529 GTNAHXXXXXXXXXXXXXXXXXGP--------GVLAWVVSARTAAGVGAQAGRLLEFVRA 1580 GTNAH P V+ WV+S + + AQA +L +V Sbjct: 5428 GTNAHTIIEQPPTREVTPTVPVAPVVPTVPTVPVVPWVLSGKGEEALRAQARQLQSYVLR 5487 Query: 1581 GRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGK 1640 EL D+ SL R+ FE RA VV A R+ LLA LA + +G G G A+ GGK Sbjct: 5488 APELRPVDIAGSLAVGRASFEDRAAVVAADREGLLAALAALADGGSATGAVEGSAV-GGK 5546 Query: 1641 TVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTT 1700 F+F GQG+Q LGMGREL YP L+ PL++V++GADA LL+ T Sbjct: 5547 LAFLFTGQGSQRLGMGRELYEAYPVFAEALDAVCARLE----LPLKDVLFGADAGLLDET 5602 Query: 1701 EFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRL 1760 + QPALFAVEVAL+RL+ESWG+RP V GHS+GE++AAHV+G RGRL Sbjct: 5603 AYTQPALFAVEVALFRLVESWGLRPDFVAGHSIGEIAAAHVAGVFSLDDACALVEARGRL 5662 Query: 1761 MQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGR 1820 M ALP GGVM AVQA E E+ PLL ++VS+AA+NGP SVV++G +V+ GR Sbjct: 5663 MGALPAGGVMIAVQASEDEVLPLLTDRVSIAAINGPRSVVIAGDEADAVAIVESFT--GR 5720 Query: 1821 RVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVR 1880 + +RL VSHAFHS M+ MLE FRAVA+ + P IPV+SN+TG LV ++ GSA++WVR Sbjct: 5721 KSKRLTVSHAFHSPHMDGMLEDFRAVAEGLSYEAPRIPVVSNLTGTLVTDEMGSAEFWVR 5780 Query: 1881 HIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFX 1940 H+REAVRF D + +AG T +VE+GP G L++L +E ++ VP LR R E Sbjct: 5781 HVREAVRFLDGIRALEAAGVTTYVELGPGGVLSALAQECVSGDGAAFVPVLRSGRSEAET 5840 Query: 1941 XXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DWA+ AG G +RV LPTYAF +R+WL Sbjct: 5841 AVTALAQAHVRGVNVDWAAFFAGTGAERVDLPTYAFQRQRYWL 5883 Score = 1002 bits (2590), Expect = 0.0 Identities = 539/989 (54%), Positives = 661/989 (66%), Gaps = 20/989 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL+ AEQ+ +L++V H AAVLG DG+ + A +AF + G SL++VELRNRL Sbjct: 1581 RLAGLTQAEQERELLSLVRLHVAAVLGHDGSDAVGAERAFKELGFDSLTSVELRNRLGAA 1640 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL--HHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 T + L T +DYPT LA++L L Q+ P AV D+PI IV M CR+ Sbjct: 1641 TDLRLPTTLVYDYPTSAALAEYLRGELAGSAQDAGPPLPAVVGSAADDDPIVIVSMSCRF 1700 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGGV +P LWQL+A G D + FP DRGWD++ L+ DP+ G +YTR GGF+ D ADF Sbjct: 1701 PGGVRTPEDLWQLLADGTDTVAAFPADRGWDLDGLYSADPERSGTSYTREGGFLYDAADF 1760 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGY---- 1243 D FFGISP EALAMDPQQRLLLET+WE E AGIDP +LRGS GVFVG G Y Sbjct: 1761 DADFFGISPREALAMDPQQRLLLETAWETFERAGIDPASLRGSQAGVFVGTNGQDYLSLV 1820 Query: 1244 ---GLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRA 1300 G G + + TG+ SV SGR+SY GL GPAI+VDTACSSSLVALHLA +LR Sbjct: 1821 TREGDGLDGLEGHVGTGNAASVVSGRLSYVFGLEGPAITVDTACSSSLVALHLAVQALRQ 1880 Query: 1301 GECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLS 1360 GEC LALAGG TV++TP F+ FSRQRGLA DGR KAFA AADGTG+ EG GML+++RLS Sbjct: 1881 GECTLALAGGVTVMSTPDAFVDFSRQRGLAEDGRIKAFASAADGTGWGEGVGMLLVERLS 1940 Query: 1361 DARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHG 1420 DARR G PVLA++ GSA+NQDGASNGLTAP+GP+QQRVI AL+ AG++ ADVD VEAHG Sbjct: 1941 DARRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALAGAGLSAADVDAVEAHG 2000 Query: 1421 TGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQL 1480 TGTRLGDPIEAQALLATYG+ D PLWLGS+KSN+GH+QAAAGVAGV+KMV AMRH + Sbjct: 2001 TGTRLGDPIEAQALLATYGQGRPADRPLWLGSVKSNIGHTQAAAGVAGVMKMVMAMRHGV 2060 Query: 1481 LPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH---XXXX 1537 LP TLH+D P+ HVDWS G V LLTE REWPA G PRRAGVSSFG+SGTNAH Sbjct: 2061 LPRTLHVDGPTPHVDWSAGDVALLTEQREWPA-TGHPRRAGVSSFGLSGTNAHTIIEEAP 2119 Query: 1538 XXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTR 1597 P VL ++SA++ AG+ AQ+ +L + ++ GD+ YSL T R Sbjct: 2120 ADDDAEPTTGAGTAPSVLPLLISAKSDAGLRAQSEQLATHLVGNPDVPIGDIAYSLTTGR 2179 Query: 1598 SLFEHRAVVVG--AGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGM 1655 S E RA++VG R L A L + G G+ G GG F+F GQG+Q LGM Sbjct: 2180 SGLETRAILVGDADNRTGLAAALRSLAAGEQAPGLVQGTVTEGG-LAFLFTGQGSQRLGM 2238 Query: 1656 GRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALY 1715 GREL YP +D L PLR+V++GA A LL+ T + QPALFAVEVAL+ Sbjct: 2239 GRELYETYPVFADALDAVCARMD--LEVPLRDVLFGAYAGLLDETAYTQPALFAVEVALF 2296 Query: 1716 RLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQA 1775 RL+ESWG+RP V GHS+GE++AAHV+G RGRLM ALPGGGVM AVQA Sbjct: 2297 RLVESWGLRPDFVAGHSIGEIAAAHVAGVLSLDDACALVEARGRLMGALPGGGVMIAVQA 2356 Query: 1776 GEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVL 1835 E E+ PLL E+VS+AA+NGP SVV++G +V+ GR+ +RL VSHAFHS Sbjct: 2357 PEAEVLPLLTERVSIAAINGPQSVVIAGDEADAVAIVESFT--GRKSKRLTVSHAFHSPH 2414 Query: 1836 MEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFA 1895 M+ MLE FRAVA+ + P IPV+SN+TG LV+++ GSA++WVRH+REAVRF D + Sbjct: 2415 MDGMLEDFRAVAEGLSYEAPRIPVVSNLTGALVSDEMGSAEFWVRHVREAVRFLDGMRVL 2474 Query: 1896 HSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXX 1955 +AG T +VE+GP G L++L +E ++ VP LR RPE Sbjct: 2475 EAAGVTTYVELGPGGVLSALAQECVSGDGAAFVPVLRSGRPEAETAVTALAQAHVRGVDV 2534 Query: 1956 DWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 DWA+ +G G QRV LPTYAF +RFW A Sbjct: 2535 DWAAFFSGTGVQRVDLPTYAFQRQRFWPA 2563 Score = 998 bits (2580), Expect = 0.0 Identities = 537/991 (54%), Positives = 651/991 (65%), Gaps = 23/991 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L AEQ +L +V H AAVLG G+ + A +AF + G SL+AVELRNRL Sbjct: 6422 RLAALGGAEQDKELLNLVRTHIAAVLGHGGSEAVGAERAFKELGFDSLTAVELRNRLGAA 6481 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TGV L AT FDYPT T LA +L L V D+PIAIV M CR+PG Sbjct: 6482 TGVRLPATLIFDYPTATALAAYLRGELLGTQVVVSGPVSNGVVVDDDPIAIVAMSCRFPG 6541 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV +P LW+L+++GGD IGEFP DRGWD+ RL+ PDPD G Y R GGF+ D ADFD Sbjct: 6542 GVRTPEDLWRLLSTGGDAIGEFPADRGWDLSRLYSPDPDKQGTFYARAGGFLYDAADFDA 6601 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ 1249 FFGISP EALAMDPQQRLLLETSWEA E AGIDP +LRGS GVFVG G YG Sbjct: 6602 DFFGISPREALAMDPQQRLLLETSWEAFERAGIDPSSLRGSQAGVFVGTNGQDYGAMLQT 6661 Query: 1250 A----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 + + TG+ SV SGR+SY GL GPA++VDTACS+SLVALH A +LR+GEC L Sbjct: 6662 IPDGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAVQALRSGECSL 6721 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV+++P +I FSRQRGLA DGR KAFA AADGTG+ EG GML+++RLSDARR Sbjct: 6722 ALAGGVTVMSSPGAYIDFSRQRGLAEDGRIKAFAAAADGTGWGEGVGMLLVERLSDARRN 6781 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSA+NQDGASNGLTAP+GP+QQRVI AL++AG++ A+VD VEAHGTGTRL Sbjct: 6782 GHPVLALVRGSAINQDGASNGLTAPNGPSQQRVIRQALANAGLSAAEVDAVEAHGTGTRL 6841 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIE QALLATYGR+ D PLWLGSIKSN+GH+QAAAGVAGVIKMV AM H +LP TL Sbjct: 6842 GDPIEVQALLATYGREREADQPLWLGSIKSNIGHTQAAAGVAGVIKMVLAMEHGVLPQTL 6901 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH-----------X 1534 H+D+P+ HVDWS G V LLT+A EWP GRPRRAGVSSFG SGTNAH Sbjct: 6902 HVDEPTPHVDWSAGDVALLTDAVEWPE-TGRPRRAGVSSFGFSGTNAHTVLEQAPKPEEP 6960 Query: 1535 XXXXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLV 1594 GV+ W +SA++ A + QA RL + + L DV YSL Sbjct: 6961 EESQQPEETNAPARPHQSGVMPWTLSAKSEAALRVQAERLRTRIASDPLLQPVDVAYSLA 7020 Query: 1595 TTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLG 1654 T+R+ E RAVVV RDE LAGL + G+P G+ G GG F+F GQG+Q LG Sbjct: 7021 TSRAALERRAVVVATERDEFLAGLKALASGQPAPGLVQGRVTEGG-LAFLFTGQGSQRLG 7079 Query: 1655 MGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVAL 1714 MGREL YP L+ PL +V++G + + L+ T + QPALFAVEVAL Sbjct: 7080 MGRELYETYPVFADALDAVCVRLE----LPLMDVLFGTERDALDETGYTQPALFAVEVAL 7135 Query: 1715 YRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQ 1774 +RL+ESWG+RP + GHS+GE++AAHV+G RGRLMQALP GGVM AVQ Sbjct: 7136 FRLVESWGVRPDFLAGHSIGEIAAAHVAGVFSLDDACALVEARGRLMQALPTGGVMIAVQ 7195 Query: 1775 AGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSV 1834 A E E+ PLL E+VS+AA+NGP SVV++G +V+ GR+ +RL VSHAFHS Sbjct: 7196 ASEAEVLPLLTERVSIAAINGPQSVVIAGDEADAVALVESFT--GRKSKRLTVSHAFHSP 7253 Query: 1835 LMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCF 1894 M+ ML FR VA+ + P IPV+SN+TG LV ++ GSAD+WVRH+REAVRF D Sbjct: 7254 HMDGMLADFRKVAEGLSYEAPRIPVVSNLTGALVTDEMGSADFWVRHVREAVRFLDGTRT 7313 Query: 1895 AHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXX 1954 + G T +VE+GP G L+++ +E + V VP LR RPE Sbjct: 7314 LEALGVTTYVELGPDGVLSAMAQECVTGEDSVFVPVLRSGRPEAESVTTALAQVHVRGIA 7373 Query: 1955 XDWASVLAGCGGQRVGLPTYAFAHERFWLAD 1985 DW + AG G QRV LPTYAF R+WL + Sbjct: 7374 VDWQAYFAGTGAQRVDLPTYAFQRRRYWLEE 7404 Score = 987 bits (2551), Expect = 0.0 Identities = 528/985 (53%), Positives = 663/985 (67%), Gaps = 16/985 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL + AEQ+ +L +V AAVLG G + AG+AF + G SL AVELRNR+ + Sbjct: 3108 RLSAQAPAEQERELLDLVRTQVAAVLGHAGVENVGAGRAFKELGFDSLMAVELRNRIGSA 3167 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 T + L AT +D+PT LA+ L L R A ++PIAIV M CR+PG Sbjct: 3168 TELRLPATLIYDHPTSAALAEFLRGELVGTVRVADKVLPAVVSADEDPIAIVSMSCRFPG 3227 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV +P LW+L+ G D +G FP DRGWD++RL+ PDPD G +YTR GGF ADFDP Sbjct: 3228 GVRTPEDLWRLLVDGTDAVGAFPADRGWDLDRLYSPDPDQPGTSYTREGGFFDGAADFDP 3287 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGY-GLGTS 1248 GFFGISP EALAMDPQQRLLLETSWEA+E AGIDP +LRGS GVFVG G Y L T Sbjct: 3288 GFFGISPREALAMDPQQRLLLETSWEAIERAGIDPSSLRGSQAGVFVGTNGQDYLSLITR 3347 Query: 1249 QAQW---YADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 +++ + TG+ SV SGR+SY LGL GPA++VDTACSSSLVALH A +LR GEC + Sbjct: 3348 ESEGLEGHLGTGNAGSVMSGRVSYVLGLEGPAVTVDTACSSSLVALHWAIQALRQGECSM 3407 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV++TP F+ FSRQRGLA DGR KAFA AADGTG+ EG GML+++RLSDARR Sbjct: 3408 ALAGGVTVMSTPENFVDFSRQRGLAEDGRIKAFASAADGTGWGEGVGMLLVERLSDARRN 3467 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSAVNQDGASNGLTAP+GP+QQRVI AAL+ AG++ ADVDVVEAHGTGT+L Sbjct: 3468 GHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALASAGLSAADVDVVEAHGTGTKL 3527 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIEAQALLATYG+D PLWLGSIKSN+GH+QAAAGVAG+IKMV AM+H +LP TL Sbjct: 3528 GDPIEAQALLATYGQDRPAGRPLWLGSIKSNIGHTQAAAGVAGIIKMVLAMQHGVLPQTL 3587 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXX 1545 H+D+P+ HVDWS G V LLTE WP V RPRRAGVSSFG+SGTNAH Sbjct: 3588 HVDEPTPHVDWSAGEVTLLTEQTAWP-TVDRPRRAGVSSFGISGTNAHTIIEQAPAVEQL 3646 Query: 1546 XXXXXGPGV------LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG--DVGYSLVTTR 1597 P L +V+SA++ + AQA L + A G D+ +SL T R Sbjct: 3647 ADGDATPATPALALPLPYVLSAKSPEALRAQASVLRTHLEATDHNGPGSDDLAFSLATAR 3706 Query: 1598 SLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGR 1657 + EHRAV+ E LA + +G P + +G A+ G+T F+F GQG+Q LGMGR Sbjct: 3707 AHLEHRAVLTADDPQEFREALARLADGDPSPRITTG-AVSDGRTAFLFTGQGSQRLGMGR 3765 Query: 1658 ELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRL 1717 EL YP +D HL PL++V++GADA LL+ T + QPALFAVEVAL+RL Sbjct: 3766 ELYEAYPVFADALDAVCAHVDAHLEVPLKDVLFGADAGLLDQTAYTQPALFAVEVALFRL 3825 Query: 1718 LESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGE 1777 +ESWG++P V GHS+GE++AAHV+G RGRLMQALP GGVM AVQA E Sbjct: 3826 VESWGVKPDFVAGHSIGEIAAAHVAGVFSLQDASELVFARGRLMQALPTGGVMIAVQASE 3885 Query: 1778 QELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLME 1837 E+ PLL ++VS+AA+NGP SVV++G EA +V + + R+ +RL VSHAFHS M+ Sbjct: 3886 DEVLPLLTDRVSIAAINGPQSVVIAG-DEADAVAIAE-SFTDRKSKRLTVSHAFHSPHMD 3943 Query: 1838 PMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHS 1897 ML+ FR +A+ + IPV+SN+TG LV+++ GSA++WVRH+REAVRF D + + Sbjct: 3944 GMLDAFREIAEGLSYEPSRIPVVSNLTGALVSDEMGSAEFWVRHVREAVRFLDGIRTLEA 4003 Query: 1898 AGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDW 1957 AG T++VE+GP G L+++ ++ ++ V +P LRK RPE DW Sbjct: 4004 AGVTKYVELGPDGVLSAMAQDCVSGEGSVFIPVLRKARPEAESVTTALASAHVHGIPVDW 4063 Query: 1958 ASVLAGCGGQRVGLPTYAFAHERFW 1982 + AG G QRV LPTYAF +R+W Sbjct: 4064 QAYFAGTGAQRVDLPTYAFQRQRYW 4088 Score = 956 bits (2472), Expect = 0.0 Identities = 515/1004 (51%), Positives = 637/1004 (63%), Gaps = 31/1004 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL++AEQ A+L V +A L LD + F D G SL+AV+L RL Sbjct: 35 RLTGLTEAEQHTALLEWVSSLASAALRDAAPDTLDPHRPFLDLGFDSLAAVDLHARLVAG 94 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAA-VRTRVRIDEPIAIVGMGCRYP 1128 TG+ L T AFD+PTP LA HL H + PA V V DEPIAIVG+GC +P Sbjct: 95 TGLRLPVTLAFDHPTPAHLARHL--HAAILGLTGPAETPVTAAVGSDEPIAIVGIGCHFP 152 Query: 1129 GGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFD 1188 GGV SP LW LV +G D I FP RGWD++ L+DPDPD G +Y R GGF+ D FD Sbjct: 153 GGVQSPEALWNLVETGTDAISAFPTGRGWDLDALYDPDPDRAGTSYAREGGFLHDADAFD 212 Query: 1189 PGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS 1248 FFGISP EALAMDPQQRLLLE SWEA + AG+DP ALRG GVFVG YG Sbjct: 213 AAFFGISPREALAMDPQQRLLLEASWEAFDRAGVDPAALRGGQVGVFVGAETQEYGPRLQ 272 Query: 1249 QA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 A + Y TG+ SVASGRI+Y G GP ++VDTACSSSL ALHLA +LR GEC Sbjct: 273 DATDGFEGYLVTGNAASVASGRIAYTFGFEGPTVTVDTACSSSLAALHLAVQALRTGECS 332 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 LALAGG V+A+P F+ FSRQRGLA DGRCK FA AADGT + EG GML+++RLSDAR Sbjct: 333 LALAGGVAVMASPGSFVSFSRQRGLAPDGRCKPFAAAADGTAWGEGVGMLLVERLSDARA 392 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 G +LA++ GSA+NQDGASNGLTAPSGP+QQRVI AL++AG++ A+VDVVEAHGTGTR Sbjct: 393 KGHRILAVVRGSAINQDGASNGLTAPSGPSQQRVIRQALANAGLSAAEVDVVEAHGTGTR 452 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG++HT D PLWLGS+KSN+GH+QAAAGVAG+IKM+ AMRH +LP T Sbjct: 453 LGDPIEAQALLATYGQEHTDDRPLWLGSLKSNIGHTQAAAGVAGIIKMIMAMRHGVLPRT 512 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D P+ HVDW G V LLTEA EWP RPRRAGVSSFG+SGTNAH Sbjct: 513 LHVDAPTPHVDWEAGAVTLLTEAVEWPE-SDRPRRAGVSSFGMSGTNAHVIVEEPAAQDR 571 Query: 1545 XXXXXXG-----------------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 1587 G P +L W +SA+T + AQA RL + A + Sbjct: 572 EGAPTSGAQAPDSSQGQAQGTSTAPVLLPWALSAKTPEALRAQARRLGTLIAAQPHVTPL 631 Query: 1588 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 1647 D+G+SL TTR FE RA+V+G R+ L L + EG V G A P GK F+F G Sbjct: 632 DIGHSLATTRGRFEQRAIVLGDDREAFLDALHALAEGNDTPSVVQGAAAP-GKLAFLFTG 690 Query: 1648 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVW----GADAELLNTTEFA 1703 QG+Q LGMGREL +P LD L PL +V++ +A LL+ T + Sbjct: 691 QGSQRLGMGRELYETHPVFADALDDACWYLDDQLELPLLDVLFADEGSPEAALLHQTAYT 750 Query: 1704 QPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA 1763 QPALFAVEVAL+RL++SWG++P V GHS+GE++AAHV+G RGRLMQA Sbjct: 751 QPALFAVEVALFRLVDSWGLKPDFVAGHSIGEIAAAHVAGVFSLEDACMLVAARGRLMQA 810 Query: 1764 LPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 1823 LP GGVM A+QA E E+ PLL ++VS+AA+NGP +VV++G +A + + + A GR+ + Sbjct: 811 LPAGGVMIALQASEDEVLPLLTDRVSIAAINGPQAVVIAGDEDAAAAIAETFQAAGRKTK 870 Query: 1824 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVA-EDYGSADYWVRHI 1882 RL VSHAFHS M+ MLE+F VA + +P +PV+S +TG + + YWVRH+ Sbjct: 871 RLTVSHAFHSPHMDAMLEEFLRVAQVLDYAKPTLPVVSLLTGTTATPAELATPAYWVRHV 930 Query: 1883 REAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXX 1942 R+AVR+ D V H G F+E+GP LT++ ++ + P LR RPE Sbjct: 931 RDAVRYLDGVRTLHQRGVRTFLELGPDAVLTAMAQDCVDPQGAAFAPALRSGRPEAATVL 990 Query: 1943 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADR 1986 DWA+ AG G QRV LPTYAF +R+W+ R Sbjct: 991 NAVAHAHVRGAETDWAAFFAGTGAQRVDLPTYAFQRQRYWMDSR 1034 Score = 718 bits (1853), Expect = 0.0 Identities = 419/974 (43%), Positives = 558/974 (57%), Gaps = 36/974 (3%) Query: 26 DSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPS----AHDVIKSVLG 81 D+ V+ D ++LG S+ + + L G+ + V+D P+ A ++ + G Sbjct: 4918 DARAVDADRAFKELGFDSLTAVELRNVLKAATGLRLSPTLVFDYPTPVALARHLLAELAG 4977 Query: 82 GDGSQ-----RSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSA 136 Q R A + A + + +PI ++GM CRF G V LW +A Sbjct: 4978 TADDQDAVRGRKAPARPATAAVTSVTGEDPIVIVGMGCRFPGGVRSPEDLWQLVATGGDG 5037 Query: 137 ITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQR 191 IT +P+ R A + D T G FL D FD FF I P EA MDPQQR Sbjct: 5038 ITGFPSDRGWNVEALYHPDPDHAGTSYTREGGFLHDAADFDPGFFGISPREALAMDPQQR 5097 Query: 192 LLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDN------TG 245 LLLETSW A E AGI P TL+ S TGVF GV DYV + GG + + TG Sbjct: 5098 LLLETSWEAFERAGIDPATLRGSRTGVFAGVMYHDYVTGIGDGGSAVELPEGVEGYLGTG 5157 Query: 246 GSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISP 305 + SI + R++Y + GP++ +DTACSSSLVA H A ++L SGEC +A+ G V+ +P Sbjct: 5158 NAGSIASGRIAYTFGLEGPAVTVDTACSSSLVALHWAIQALRSGECTMALAGGVAVMATP 5217 Query: 306 EVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSA 365 E + F +S G C++F A ADG EG G++++ERLSDA R G VLAV+ GSA Sbjct: 5218 ETFVDFSRQRGLSADGRCKSFAAAADGTGWAEGAGMLLVERLSDAERNGHPVLAVVRGSA 5277 Query: 366 VNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQV 425 +NQDG SNG+ APN +Q V+ A AD+ A+ID VEAHGTGT +GD IEA AL Sbjct: 5278 INQDGASNGLTAPNGPSQQRVIREALASADLSAADIDAVEAHGTGTRLGDPIEAQALLAT 5337 Query: 426 FGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFA 485 +GR R+A +PL +GSIK NIGH + AAG+AG+IK V+ ++ G L + + P+P + + Sbjct: 5338 YGREREAGRPLWLGSIKSNIGHTQAAAGVAGIIKMVMAMRHGVLPQTLHVDEPSPQVDWE 5397 Query: 486 ELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP----- 540 ++++ WP GRPRRAGVSSFG GTNAH P Sbjct: 5398 AGEVSLLTGAMPWPQ-TGRPRRAGVSSFGISGTNAHTIIEQPPTREVTPTVPVAPVVPTV 5456 Query: 541 ---GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGA 597 V+ WV+S + + AQA +L +V EL D+ SL R+ FE RA VV A Sbjct: 5457 PTVPVVPWVLSGKGEEALRAQARQLQSYVLRAPELRPVDIAGSLAVGRASFEDRAAVVAA 5516 Query: 598 GRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXX 657 R+ LLA LA + +G G G A+ GGK F+F GQG+Q LGMGREL YP Sbjct: 5517 DREGLLAALAALADGGSATGAVEGSAV-GGKLAFLFTGQGSQRLGMGRELYEAYPVFAEA 5575 Query: 658 XXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVM 717 L+ PL++V++GADA LL+ T + QPALFAVEVAL+RL+ESWG+RP V Sbjct: 5576 LDAVCARLE----LPLKDVLFGADAGLLDETAYTQPALFAVEVALFRLVESWGLRPDFVA 5631 Query: 718 GHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVS 777 GHS+GE++AAHV+G RGRLM ALP GGVM AVQA E E+ PLL ++VS Sbjct: 5632 GHSIGEIAAAHVAGVFSLDDACALVEARGRLMGALPAGGVMIAVQASEDEVLPLLTDRVS 5691 Query: 778 VAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADE 837 +AA+NGP SVV++G +V+ GR+ +RL VSHAFHS M+ MLE FRAVA+ Sbjct: 5692 IAAINGPRSVVIAGDEADAVAIVESFT--GRKSKRLTVSHAFHSPHMDGMLEDFRAVAEG 5749 Query: 838 VYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPA 897 + P IPV+SN+TG LV ++ GSA++WVRH+REAVRF D + +AG T +VE+GP Sbjct: 5750 LSYEAPRIPVVSNLTGTLVTDEMGSAEFWVRHVREAVRFLDGIRALEAAGVTTYVELGPG 5809 Query: 898 GGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRV 957 G L++L +E ++ VP LR R E DWA+ AG G +RV Sbjct: 5810 GVLSALAQECVSGDGAAFVPVLRSGRSEAETAVTALAQAHVRGVNVDWAAFFAGTGAERV 5869 Query: 958 GLPTYAFAHERFWL 971 LPTYAF +R+WL Sbjct: 5870 DLPTYAFQRQRYWL 5883 Score = 715 bits (1846), Expect = 0.0 Identities = 422/978 (43%), Positives = 565/978 (57%), Gaps = 34/978 (3%) Query: 16 THYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV 75 TH A S V + ++LG S+ + + L G+ +P ++D P+A Sbjct: 6441 THIAAVLGHGGSEAVGAERAFKELGFDSLTAVELRNRLGAATGVRLPATLIFDYPTA-TA 6499 Query: 76 IKSVLGGD--GSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEK 133 + + L G+ G+Q V+ + ++PIA++ M+CRF G V LW L+ Sbjct: 6500 LAAYLRGELLGTQVVVSGPVSNGVVVD---DDPIAIVAMSCRFPGGVRTPEDLWRLLSTG 6556 Query: 134 KSAITEYPARRLGAAAADWLGD--EQETIY---GCFLEDVEGFDNKFFDIPPDEAALMDP 188 AI E+PA R + + D +Q T Y G FL D FD FF I P EA MDP Sbjct: 6557 GDAIGEFPADRGWDLSRLYSPDPDKQGTFYARAGGFLYDAADFDADFFGISPREALAMDP 6616 Query: 189 QQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLL--FPGGRKPTIWDNTGG 246 QQRLLLETSW A E AGI P +L+ S GVFVG + DY +L P G + + TG Sbjct: 6617 QQRLLLETSWEAFERAGIDPSSLRGSQAGVFVGTNGQDYGAMLQTIPDGIEGFL--GTGN 6674 Query: 247 SSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPE 306 ++S+++ RLSY + GP++ +DTACS+SLVA H A ++L SGEC LA+ G V+ SP Sbjct: 6675 AASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAVQALRSGECSLALAGGVTVMSSPG 6734 Query: 307 VWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAV 366 + F ++ G +AF A ADG GEG G++++ERLSDARR G VLA++ GSA+ Sbjct: 6735 AYIDFSRQRGLAEDGRIKAFAAAADGTGWGEGVGMLLVERLSDARRNGHPVLALVRGSAI 6794 Query: 367 NQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVF 426 NQDG SNG+ APN +Q V+ A A + AE+D VEAHGTGT +GD IE AL + Sbjct: 6795 NQDGASNGLTAPNGPSQQRVIRQALANAGLSAAEVDAVEAHGTGTRLGDPIEVQALLATY 6854 Query: 427 GRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAE 486 GR R+A +PL +GSIK NIGH + AAG+AG+IK VL ++ G L + + P P++ ++ Sbjct: 6855 GREREADQPLWLGSIKSNIGHTQAAAGVAGVIKMVLAMEHGVLPQTLHVDEPTPHVDWSA 6914 Query: 487 LGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH-----------XXXXXXXXXXXXXX 535 +A++ + EWP GRPRRAGVSSFGF GTNAH Sbjct: 6915 GDVALLTDAVEWPE-TGRPRRAGVSSFGFSGTNAHTVLEQAPKPEEPEESQQPEETNAPA 6973 Query: 536 XXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVV 595 GV+ W +SA++ A + QA RL + + L DV YSL T+R+ E RAVVV Sbjct: 6974 RPHQSGVMPWTLSAKSEAALRVQAERLRTRIASDPLLQPVDVAYSLATSRAALERRAVVV 7033 Query: 596 GAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXX 655 RDE LAGL + G+P G+ G GG F+F GQG+Q LGMGREL YP Sbjct: 7034 ATERDEFLAGLKALASGQPAPGLVQGRVTEGG-LAFLFTGQGSQRLGMGRELYETYPVFA 7092 Query: 656 XXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGL 715 L+ PL +V++G + + L+ T + QPALFAVEVAL+RL+ESWG+RP Sbjct: 7093 DALDAVCVRLE----LPLMDVLFGTERDALDETGYTQPALFAVEVALFRLVESWGVRPDF 7148 Query: 716 VMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQ 775 + GHS+GE++AAHV+G RGRLMQALP GGVM AVQA E E+ PLL E+ Sbjct: 7149 LAGHSIGEIAAAHVAGVFSLDDACALVEARGRLMQALPTGGVMIAVQASEAEVLPLLTER 7208 Query: 776 VSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVA 835 VS+AA+NGP SVV++G +V+ GR+ +RL VSHAFHS M+ ML FR VA Sbjct: 7209 VSIAAINGPQSVVIAGDEADAVALVESFT--GRKSKRLTVSHAFHSPHMDGMLADFRKVA 7266 Query: 836 DEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVG 895 + + P IPV+SN+TG LV ++ GSAD+WVRH+REAVRF D + G T +VE+G Sbjct: 7267 EGLSYEAPRIPVVSNLTGALVTDEMGSADFWVRHVREAVRFLDGTRTLEALGVTTYVELG 7326 Query: 896 PAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQ 955 P G L+++ +E + V VP LR RPE DW + AG G Q Sbjct: 7327 PDGVLSAMAQECVTGEDSVFVPVLRSGRPEAESVTTALAQVHVRGIAVDWQAYFAGTGAQ 7386 Query: 956 RVGLPTYAFAHERFWLAD 973 RV LPTYAF R+WL + Sbjct: 7387 RVDLPTYAFQRRRYWLEE 7404 Score = 714 bits (1844), Expect = 0.0 Identities = 413/969 (42%), Positives = 568/969 (58%), Gaps = 20/969 (2%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVI 76 ++AA G D ++ V + ++LG S+ + + L + +P V+D P++ + Sbjct: 1601 HVAAVLGHDGSDAVGAERAFKELGFDSLTSVELRNRLGAATDLRLPTTLVYDYPTSAALA 1660 Query: 77 KSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSA 136 + + G AV+G+ ++PI ++ M+CRF G V LW LA+ Sbjct: 1661 EYLRGELAGSAQDAGPPLPAVVGSAADDDPIVIVSMSCRFPGGVRTPEDLWQLLADGTDT 1720 Query: 137 ITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQR 191 + +PA R + D + T G FL D FD FF I P EA MDPQQR Sbjct: 1721 VAAFPADRGWDLDGLYSADPERSGTSYTREGGFLYDAADFDADFFGISPREALAMDPQQR 1780 Query: 192 LLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDN---TGGSS 248 LLLET+W E AGI P +L+ S GVFVG + DY+ L+ G + TG ++ Sbjct: 1781 LLLETAWETFERAGIDPASLRGSQAGVFVGTNGQDYLSLVTREGDGLDGLEGHVGTGNAA 1840 Query: 249 SIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVW 308 S+++ RLSY + GP++ +DTACSSSLVA HLA ++L GEC LA+ G V+ +P+ + Sbjct: 1841 SVVSGRLSYVFGLEGPAITVDTACSSSLVALHLAVQALRQGECTLALAGGVTVMSTPDAF 1900 Query: 309 RGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQ 368 F ++ G +AF + ADG GEG G++++ERLSDARR G VLAV+ GSA+NQ Sbjct: 1901 VDFSRQRGLAEDGRIKAFASAADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGSAINQ 1960 Query: 369 DGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGR 428 DG SNG+ APN +Q V+ A A + A++D VEAHGTGT +GD IEA AL +G+ Sbjct: 1961 DGASNGLTAPNGPSQQRVIRQALAGAGLSAADVDAVEAHGTGTRLGDPIEAQALLATYGQ 2020 Query: 429 GRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELG 488 GR A +PL +GS+K NIGH + AAG+AG++K V+ ++ G L + + P P++ ++ Sbjct: 2021 GRPADRPLWLGSVKSNIGHTQAAAGVAGVMKMVMAMRHGVLPRTLHVDGPTPHVDWSAGD 2080 Query: 489 LAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH---XXXXXXXXXXXXXXXXXGPGVLAW 545 +A++ E +EWPA G PRRAGVSSFG GTNAH P VL Sbjct: 2081 VALLTEQREWPA-TGHPRRAGVSSFGLSGTNAHTIIEEAPADDDAEPTTGAGTAPSVLPL 2139 Query: 546 VVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVG--AGRDELL 603 ++SA++ AG+ AQ+ +L + ++ GD+ YSL T RS E RA++VG R L Sbjct: 2140 LISAKSDAGLRAQSEQLATHLVGNPDVPIGDIAYSLTTGRSGLETRAILVGDADNRTGLA 2199 Query: 604 AGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXX 663 A L + G G+ G GG F+F GQG+Q LGMGREL YP Sbjct: 2200 AALRSLAAGEQAPGLVQGTVTEGG-LAFLFTGQGSQRLGMGRELYETYPVFADALDAVCA 2258 Query: 664 ELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGE 723 +D L PLR+V++GA A LL+ T + QPALFAVEVAL+RL+ESWG+RP V GHS+GE Sbjct: 2259 RMD--LEVPLRDVLFGAYAGLLDETAYTQPALFAVEVALFRLVESWGLRPDFVAGHSIGE 2316 Query: 724 LSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNG 783 ++AAHV+G RGRLM ALPGGGVM AVQA E E+ PLL E+VS+AA+NG Sbjct: 2317 IAAAHVAGVLSLDDACALVEARGRLMGALPGGGVMIAVQAPEAEVLPLLTERVSIAAING 2376 Query: 784 PGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRP 843 P SVV++G +V+ GR+ +RL VSHAFHS M+ MLE FRAVA+ + P Sbjct: 2377 PQSVVIAGDEADAVAIVESFT--GRKSKRLTVSHAFHSPHMDGMLEDFRAVAEGLSYEAP 2434 Query: 844 AIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSL 903 IPV+SN+TG LV+++ GSA++WVRH+REAVRF D + +AG T +VE+GP G L++L Sbjct: 2435 RIPVVSNLTGALVSDEMGSAEFWVRHVREAVRFLDGMRVLEAAGVTTYVELGPGGVLSAL 2494 Query: 904 IEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYA 963 +E ++ VP LR RPE DWA+ +G G QRV LPTYA Sbjct: 2495 AQECVSGDGAAFVPVLRSGRPEAETAVTALAQAHVRGVDVDWAAFFSGTGVQRVDLPTYA 2554 Query: 964 FAHERFWLA 972 F +RFW A Sbjct: 2555 FQRQRFWPA 2563 Score = 695 bits (1794), Expect = 0.0 Identities = 402/949 (42%), Positives = 559/949 (58%), Gaps = 23/949 (2%) Query: 37 RDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGG-DGSQRSADSDTGC 95 ++LG S+ + + + + +P ++D+P++ + + + G G+ R AD Sbjct: 3148 KELGFDSLMAVELRNRIGSATELRLPATLIYDHPTSAALAEFLRGELVGTVRVADKVLPA 3207 Query: 96 AVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARR------LGAAA 149 V + +PIA++ M+CRF G V LW L + A+ +PA R L + Sbjct: 3208 VVSAD---EDPIAIVSMSCRFPGGVRTPEDLWRLLVDGTDAVGAFPADRGWDLDRLYSPD 3264 Query: 150 ADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPK 209 D G T G F + FD FF I P EA MDPQQRLLLETSW A+E AGI P Sbjct: 3265 PDQPGTSY-TREGGFFDGAADFDPGFFGISPREALAMDPQQRLLLETSWEAIERAGIDPS 3323 Query: 210 TLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVID 269 +L+ S GVFVG + DY+ L+ TG + S+++ R+SY L + GP++ +D Sbjct: 3324 SLRGSQAGVFVGTNGQDYLSLITRESEGLEGHLGTGNAGSVMSGRVSYVLGLEGPAVTVD 3383 Query: 270 TACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDAR 329 TACSSSLVA H A ++L GEC +A+ G V+ +PE + F ++ G +AF + Sbjct: 3384 TACSSSLVALHWAIQALRQGECSMALAGGVTVMSTPENFVDFSRQRGLAEDGRIKAFASA 3443 Query: 330 ADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDS 389 ADG GEG G++++ERLSDARR G VLAV+ GSAVNQDG SNG+ APN +Q V+ + Sbjct: 3444 ADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRA 3503 Query: 390 ACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLE 449 A A + A++D VEAHGTGT +GD IEA AL +G+ R A +PL +GSIK NIGH + Sbjct: 3504 ALASAGLSAADVDVVEAHGTGTKLGDPIEAQALLATYGQDRPAGRPLWLGSIKSNIGHTQ 3563 Query: 450 GAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAG 509 AAG+AG+IK VL +Q G L + + P P++ ++ + ++ E WP V RPRRAG Sbjct: 3564 AAAGVAGIIKMVLAMQHGVLPQTLHVDEPTPHVDWSAGEVTLLTEQTAWP-TVDRPRRAG 3622 Query: 510 VSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPGV------LAWVVSARTAAGVGAQAGRLL 563 VSSFG GTNAH P L +V+SA++ + AQA L Sbjct: 3623 VSSFGISGTNAHTIIEQAPAVEQLADGDATPATPALALPLPYVLSAKSPEALRAQASVLR 3682 Query: 564 EFVRAGRELDAG--DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASG 621 + A G D+ +SL T R+ EHRAV+ E LA + +G P + +G Sbjct: 3683 THLEATDHNGPGSDDLAFSLATARAHLEHRAVLTADDPQEFREALARLADGDPSPRITTG 3742 Query: 622 VAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGAD 681 A+ G+T F+F GQG+Q LGMGREL YP +D HL PL++V++GAD Sbjct: 3743 -AVSDGRTAFLFTGQGSQRLGMGRELYEAYPVFADALDAVCAHVDAHLEVPLKDVLFGAD 3801 Query: 682 AELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXX 741 A LL+ T + QPALFAVEVAL+RL+ESWG++P V GHS+GE++AAHV+G Sbjct: 3802 AGLLDQTAYTQPALFAVEVALFRLVESWGVKPDFVAGHSIGEIAAAHVAGVFSLQDASEL 3861 Query: 742 XXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVD 801 RGRLMQALP GGVM AVQA E E+ PLL ++VS+AA+NGP SVV++G EA +V + Sbjct: 3862 VFARGRLMQALPTGGVMIAVQASEDEVLPLLTDRVSIAAINGPQSVVIAG-DEADAVAIA 3920 Query: 802 RLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYG 861 + R+ +RL VSHAFHS M+ ML+ FR +A+ + IPV+SN+TG LV+++ G Sbjct: 3921 E-SFTDRKSKRLTVSHAFHSPHMDGMLDAFREIAEGLSYEPSRIPVVSNLTGALVSDEMG 3979 Query: 862 SADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRK 921 SA++WVRH+REAVRF D + +AG T++VE+GP G L+++ ++ ++ V +P LRK Sbjct: 3980 SAEFWVRHVREAVRFLDGIRTLEAAGVTKYVELGPDGVLSAMAQDCVSGEGSVFIPVLRK 4039 Query: 922 DRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 RPE DW + AG G QRV LPTYAF +R+W Sbjct: 4040 ARPEAESVTTALASAHVHGIPVDWQAYFAGTGAQRVDLPTYAFQRQRYW 4088 Score = 671 bits (1732), Expect = 0.0 Identities = 401/1004 (39%), Positives = 552/1004 (54%), Gaps = 55/1004 (5%) Query: 10 ALQEWFTHYIAARTGCDSAEVNLD--LPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVW 67 AL EW + +A D+A LD P DLG S+ + + L G+ +P + Sbjct: 47 ALLEWVSSLASAALR-DAAPDTLDPHRPFLDLGFDSLAAVDLHARLVAGTGLRLPVTLAF 105 Query: 68 DNPS----AHDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGV 123 D+P+ A + ++LG G A++ AV ++EPIA++G+ C F G V Sbjct: 106 DHPTPAHLARHLHAAILGLTGP---AETPVTAAV----GSDEPIAIVGIGCHFPGGVQSP 158 Query: 124 GPLWDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETIY---GCFLEDVEGFDNKFFDI 178 LW+ + AI+ +P R A D D T Y G FL D + FD FF I Sbjct: 159 EALWNLVETGTDAISAFPTGRGWDLDALYDPDPDRAGTSYAREGGFLHDADAFDAAFFGI 218 Query: 179 PPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKP 238 P EA MDPQQRLLLE SW A + AG+ P L+ GVFVG + +Y G R Sbjct: 219 SPREALAMDPQQRLLLEASWEAFDRAGVDPAALRGGQVGVFVGAETQEY------GPRLQ 272 Query: 239 TIWDN------TGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECD 292 D TG ++S+ + R++Y GP++ +DTACSSSL A HLA ++L +GEC Sbjct: 273 DATDGFEGYLVTGNAASVASGRIAYTFGFEGPTVTVDTACSSSLAALHLAVQALRTGECS 332 Query: 293 LAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARR 352 LA+ G V+ SP + F ++P G C+ F A ADG GEG G++++ERLSDAR Sbjct: 333 LALAGGVAVMASPGSFVSFSRQRGLAPDGRCKPFAAAADGTAWGEGVGMLLVERLSDARA 392 Query: 353 AGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTS 412 G +LAV+ GSA+NQDG SNG+ AP+ +Q V+ A A + AE+D VEAHGTGT Sbjct: 393 KGHRILAVVRGSAINQDGASNGLTAPSGPSQQRVIRQALANAGLSAAEVDVVEAHGTGTR 452 Query: 413 VGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPS 472 +GD IEA AL +G+ +PL +GS+K NIGH + AAG+AG+IK ++ ++ G L + Sbjct: 453 LGDPIEAQALLATYGQEHTDDRPLWLGSLKSNIGHTQAAAGVAGIIKMIMAMRHGVLPRT 512 Query: 473 GAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXX 532 + P P++ + + ++ E EWP RPRRAGVSSFG GTNAH Sbjct: 513 LHVDAPTPHVDWEAGAVTLLTEAVEWPES-DRPRRAGVSSFGMSGTNAHVIVEEPAAQDR 571 Query: 533 XXXXXXG-----------------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG 575 G P +L W +SA+T + AQA RL + A + Sbjct: 572 EGAPTSGAQAPDSSQGQAQGTSTAPVLLPWALSAKTPEALRAQARRLGTLIAAQPHVTPL 631 Query: 576 DVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPG 635 D+G+SL TTR FE RA+V+G R+ L L + EG V G A PG K F+F G Sbjct: 632 DIGHSLATTRGRFEQRAIVLGDDREAFLDALHALAEGNDTPSVVQGAAAPG-KLAFLFTG 690 Query: 636 QGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG----ADAELLNTTEFA 691 QG+Q LGMGREL +P LD L PL +V++ +A LL+ T + Sbjct: 691 QGSQRLGMGRELYETHPVFADALDDACWYLDDQLELPLLDVLFADEGSPEAALLHQTAYT 750 Query: 692 QPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA 751 QPALFAVEVAL+RL++SWG++P V GHS+GE++AAHV+G RGRLMQA Sbjct: 751 QPALFAVEVALFRLVDSWGLKPDFVAGHSIGEIAAAHVAGVFSLEDACMLVAARGRLMQA 810 Query: 752 LPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 LP GGVM A+QA E E+ PLL ++VS+AA+NGP +VV++G +A + + + A GR+ + Sbjct: 811 LPAGGVMIALQASEDEVLPLLTDRVSIAAINGPQAVVIAGDEDAAAAIAETFQAAGRKTK 870 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVA-EDYGSADYWVRHI 870 RL VSHAFHS M+ MLE+F VA + +P +PV+S +TG + + YWVRH+ Sbjct: 871 RLTVSHAFHSPHMDAMLEEFLRVAQVLDYAKPTLPVVSLLTGTTATPAELATPAYWVRHV 930 Query: 871 REAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXX 930 R+AVR+ D V H G F+E+GP LT++ ++ + P LR RPE Sbjct: 931 RDAVRYLDGVRTLHQRGVRTFLELGPDAVLTAMAQDCVDPQGAAFAPALRSGRPEAATVL 990 Query: 931 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADR 974 DWA+ AG G QRV LPTYAF +R+W+ R Sbjct: 991 NAVAHAHVRGAETDWAAFFAGTGAQRVDLPTYAFQRQRYWMDSR 1034 Score = 90.1 bits (222), Expect = 4e-15 Identities = 47/104 (45%), Positives = 63/104 (60%) Query: 2023 LQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLT 2082 L+G+S E + VL +V A VLG GA ++A +AF + G SL+AVELRNRL T T Sbjct: 7981 LRGMSGTEAEGVVLNLVRTQVAVVLGHGGATAVEAARAFKELGFDSLTAVELRNRLSTAT 8040 Query: 2083 GVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDAL 2126 G+ L A+ FDYPTP LA H+ + L ++ T P L +D L Sbjct: 8041 GLRLPASLVFDYPTPAALAAHIRAELLGEDTTPELPALAEIDKL 8084 Score = 87.4 bits (215), Expect = 2e-14 Identities = 46/87 (52%), Positives = 56/87 (64%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L DAE++ +L +VC A VLG A +DA +AF + G SL+AVELRN LK Sbjct: 4889 RLSALPDAEREDMLLDLVCGRVAEVLGHTDARAVDADRAFKELGFDSLTAVELRNVLKAA 4948 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ LS T FDYPTP LA HLL+ L Sbjct: 4949 TGLRLSPTLVFDYPTPVALARHLLAEL 4975 Score = 83.2 bits (204), Expect = 4e-13 Identities = 42/86 (48%), Positives = 55/86 (63%) Query: 1011 LQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLT 1070 L+G+S E + VL +V A VLG GA ++A +AF + G SL+AVELRNRL T T Sbjct: 7981 LRGMSGTEAEGVVLNLVRTQVAVVLGHGGATAVEAARAFKELGFDSLTAVELRNRLSTAT 8040 Query: 1071 GVTLSATTAFDYPTPTQLADHLLSHL 1096 G+ L A+ FDYPTP LA H+ + L Sbjct: 8041 GLRLPASLVFDYPTPAALAAHIRAEL 8066 Score = 80.1 bits (196), Expect = 4e-12 Identities = 59/158 (37%), Positives = 82/158 (51%), Gaps = 16/158 (10%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL+ AEQ+ +L++V H AAVLG DG+ + A +AF + G SL++VELRNRL Sbjct: 1581 RLAGLTQAEQERELLSLVRLHVAAVLGHDGSDAVGAERAFKELGFDSLTSVELRNRLGAA 1640 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 T + L T +DYPT LA++L L + A P L V + DDD Sbjct: 1641 TDLRLPTTLVYDYPTSAALAEYLRGEL-AGSAQDAGPPLPAV----------VGSAADDD 1689 Query: 2142 GWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDVA 2179 IV+++ + T P+ W+ LLA G VA Sbjct: 1690 PIVIVSMSCRFPGGVRT--PEDLWQ---LLADGTDTVA 1722 Score = 79.7 bits (195), Expect = 5e-12 Identities = 45/87 (51%), Positives = 53/87 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L AEQ +L +V H AAVLG G+ + A +AF + G SL+AVELRNRL Sbjct: 6422 RLAALGGAEQDKELLNLVRTHIAAVLGHGGSEAVGAERAFKELGFDSLTAVELRNRLGAA 6481 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TGV L AT FDYPT T LA +L L Sbjct: 6482 TGVRLPATLIFDYPTATALAAYLRGEL 6508 Score = 68.9 bits (167), Expect = 8e-09 Identities = 38/87 (43%), Positives = 51/87 (58%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL + AEQ+ +L +V AAVLG G + AG+AF + G SL AVELRNR+ + Sbjct: 3108 RLSAQAPAEQERELLDLVRTQVAAVLGHAGVENVGAGRAFKELGFDSLMAVELRNRIGSA 3167 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 T + L AT +D+PT LA+ L L Sbjct: 3168 TELRLPATLIYDHPTSAALAEFLRGEL 3194 Score = 65.9 bits (159), Expect = 7e-08 Identities = 38/83 (45%), Positives = 47/83 (56%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL++AEQ A+L V +A L LD + F D G SL+AV+L RL Sbjct: 35 RLTGLTEAEQHTALLEWVSSLASAALRDAAPDTLDPHRPFLDLGFDSLAAVDLHARLVAG 94 Query: 2082 TGVTLSATTAFDYPTPTQLADHL 2104 TG+ L T AFD+PTP LA HL Sbjct: 95 TGLRLPVTLAFDHPTPAHLARHL 117 >tr|A0PQ25|A0PQ25_MYCUA Tax_Id=362242 (pks15/1)SubName: Full=Polyketide synthase Pks15/1;[Mycobacterium ulcerans] Length = 2104 Score = 1018 bits (2631), Expect = 0.0 Identities = 532/878 (60%), Positives = 619/878 (70%), Gaps = 10/878 (1%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 R EP+A+VG+GCR+PGG P LW LV+ G D + EFP DRGWD E LFDPDPDA GK Sbjct: 39 RATEPVAVVGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAEGK 98 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 TYTR G FV + +FD GFFGI P E LAMDPQQRL+LE SWEALE AGIDP +LRGSST Sbjct: 99 TYTRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHAGIDPMSLRGSST 158 Query: 1233 GVFVGIYGDGYG-LGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 GVF GI+ YG Q Y TG SVASGR++Y LGL GPA+SVDTACSSSLVA+ Sbjct: 159 GVFTGIFAPSYGGKDVGALQGYGLTGSPVSVASGRVAYVLGLEGPALSVDTACSSSLVAI 218 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 H A SLR+GECD+ALAGG TV+ PSIF+GFSRQRGLA DGRCKAFA AADGTG+ EGA Sbjct: 219 HWAMASLRSGECDMALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWGEGA 278 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 G+LVL+RLSDA+R G VLA++ GSA+NQDGASNGLTAP+G QQRVI AAL++ G+T A Sbjct: 279 GVLVLERLSDAQRNGHNVLAVVRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSA 338 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 DVDVVEAHGT T LGDPIEA+ALLATYG+ D PLW+GSIKSNMGH+QAAAGVAGVIK Sbjct: 339 DVDVVEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAGVAGVIK 398 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV+AMRH L+PA+LH+D+PS VDW G V +L EAR+WP GRPRRAGVSSFG+SGTN Sbjct: 399 MVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPD-AGRPRRAGVSSFGISGTN 457 Query: 1532 AHXXXXXXXXXXXXXXXXXGPG-----VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 1586 AH G V+ WV+SAR+A + AQAGRLL V+A + + Sbjct: 458 AHVILEEAPAPEAVPDSESNKGEPSLPVVPWVISARSAEALTAQAGRLLAHVQADPQSNP 517 Query: 1587 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFP 1646 D+G+SL RS FEHRAVVVGA R +LL GLA + +G PG GV +G A GKT VFP Sbjct: 518 VDIGFSL-AGRSAFEHRAVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAVVFP 576 Query: 1647 GQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPA 1706 GQG+Q +GM REL P ELDRHL PL EV+WG+D LL++TEFAQ A Sbjct: 577 GQGSQRIGMARELHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSDVALLDSTEFAQAA 636 Query: 1707 LFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPG 1766 LFAVEVAL+ L+ WG++P VMGHSVGELSAA+V+G RGRLMQALP Sbjct: 637 LFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVAGVLTLVDAAMLVVARGRLMQALPA 696 Query: 1767 GGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLA 1826 GG M AV A E E+ P L + V +AA+N P SVV+SGA AV+ + D+ A QGRRV RLA Sbjct: 697 GGAMVAVAAAEDEVLPSLTDGVGIAAINAPKSVVISGAEAAVTAISDQFAQQGRRVHRLA 756 Query: 1827 VSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED--YGSADYWVRHIRE 1884 VSHAFHS LMEPMLE+F +A +V A P I ++SNVTG+L + D +GSA YWV H+R Sbjct: 757 VSHAFHSPLMEPMLEEFARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRR 816 Query: 1885 AVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXX 1944 AVRFADS H+ G T FVEVGP GLT IE+SLA V V L KDRPE Sbjct: 817 AVRFADSARQLHTLGVTHFVEVGPGSGLTGSIEQSLAPAEAVVVSMLGKDRPEVASVLTA 876 Query: 1945 XXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 DW +V AG G RV LPTYAF RFW Sbjct: 877 FGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFW 914 Score = 777 bits (2007), Expect = 0.0 Identities = 432/881 (49%), Positives = 543/881 (61%), Gaps = 23/881 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGDEQE-----T 159 EP+AV+G+ CRF G G LWD +++ + A+TE+P R + D T Sbjct: 42 EPVAVVGIGCRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAEGKTYT 101 Query: 160 IYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVF 219 +G F+E+ FD FF IPP E MDPQQRL+LE SW ALEHAGI P +L+ S TGVF Sbjct: 102 RWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHAGIDPMSLRGSSTGVF 161 Query: 220 VGVSSTDYVRLLFPGGRKPTIWDN---TGGSSSIIANRLSYFLDVNGPSLVIDTACSSSL 276 G+ + Y GG+ TG S+ + R++Y L + GP+L +DTACSSSL Sbjct: 162 TGIFAPSY------GGKDVGALQGYGLTGSPVSVASGRVAYVLGLEGPALSVDTACSSSL 215 Query: 277 VAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRG 336 VA H A SL SGECD+A+ G V+ P ++ GF ++ G C+AF A ADG G Sbjct: 216 VAIHWAMASLRSGECDMALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFAAAADGTGWG 275 Query: 337 EGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADI 396 EG GV+VLERLSDA+R G VLAV+ GSA+NQDG SNG+ APN Q V+ +A + Sbjct: 276 EGAGVLVLERLSDAQRNGHNVLAVVRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGL 335 Query: 397 DPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAG 456 A++D VEAHGT T++GD IEA AL +G+GR +PL +GSIK N+GH + AAG+AG Sbjct: 336 TSADVDVVEAHGTATTLGDPIEAEALLATYGQGRPTDQPLWVGSIKSNMGHTQAAAGVAG 395 Query: 457 LIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFG 516 +IK V ++ G + S + P+ + + ++V+ E ++WP GRPRRAGVSSFG Sbjct: 396 VIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPDA-GRPRRAGVSSFGIS 454 Query: 517 GTNAHXXXXXXXXXXXXXXXXXGPG-----VLAWVVSARTAAGVGAQAGRLLEFVRAGRE 571 GTNAH G V+ WV+SAR+A + AQAGRLL V+A + Sbjct: 455 GTNAHVILEEAPAPEAVPDSESNKGEPSLPVVPWVISARSAEALTAQAGRLLAHVQADPQ 514 Query: 572 LDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVF 631 + D+G+SL RS FEHRAVVVGA R +LL GLA + +G PG GV +G A GKT Sbjct: 515 SNPVDIGFSLAG-RSAFEHRAVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKTAV 573 Query: 632 VFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFA 691 VFPGQG+Q +GM REL P ELDRHL PL EV+WG+D LL++TEFA Sbjct: 574 VFPGQGSQRIGMARELHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGSDVALLDSTEFA 633 Query: 692 QPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQA 751 Q ALFAVEVAL+ L+ WG++P VMGHSVGELSAA+V+G RGRLMQA Sbjct: 634 QAALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVAGVLTLVDAAMLVVARGRLMQA 693 Query: 752 LPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVR 811 LP GG M AV A E E+ P L + V +AA+N P SVV+SGA AV+ + D+ A QGRRV Sbjct: 694 LPAGGAMVAVAAAEDEVLPSLTDGVGIAAINAPKSVVISGAEAAVTAISDQFAQQGRRVH 753 Query: 812 RLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAED--YGSADYWVRH 869 RLAVSHAFHS LMEPMLE+F +A +V A P I ++SNVTG+L + D +GSA YWV H Sbjct: 754 RLAVSHAFHSPLMEPMLEEFARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEH 813 Query: 870 IREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXX 929 +R AVRFADS H+ G T FVEVGP GLT IE+SLA V V L KDRPE Sbjct: 814 VRRAVRFADSARQLHTLGVTHFVEVGPGSGLTGSIEQSLAPAEAVVVSMLGKDRPEVASV 873 Query: 930 XXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 DW +V AG G RV LPTYAF RFW Sbjct: 874 LTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFW 914 Score = 86.7 bits (213), Expect = 4e-14 Identities = 45/98 (45%), Positives = 59/98 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GLS E+Q A++ +VC AAVLGR +D F D G SL+AVELRNR K+ Sbjct: 1993 RLNGLSAGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNRFKSA 2052 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPE 2119 TG+TL T FD+PTPT +A+++ + T A E Sbjct: 2053 TGLTLPPTVIFDHPTPTAIAEYVGRQIPDSQATQAEEE 2090 Score = 85.5 bits (210), Expect = 9e-14 Identities = 42/83 (50%), Positives = 55/83 (66%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GLS E+Q A++ +VC AAVLGR +D F D G SL+AVELRNR K+ Sbjct: 1993 RLNGLSAGERQDALVGLVCLQAAAVLGRPSPEDIDPEAGFQDLGFDSLTAVELRNRFKSA 2052 Query: 1070 TGVTLSATTAFDYPTPTQLADHL 1092 TG+TL T FD+PTPT +A+++ Sbjct: 2053 TGLTLPPTVIFDHPTPTAIAEYV 2075 >tr|Q52V49|Q52V49_9ACTO Tax_Id=255848 SubName: Full=Polyketide synthase type I;[Streptomyces aizunensis] Length = 3872 Score = 1014 bits (2622), Expect = 0.0 Identities = 547/990 (55%), Positives = 660/990 (66%), Gaps = 25/990 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 +L GL+ ++ AAV+ +V AAVLG G +D ++FS+ G SL+AVELRNRL Sbjct: 1693 KLAGLAVDQRSAAVMELVRAQVAAVLGLAGPEAVDPARSFSEVGFDSLTAVELRNRLGAA 1752 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TGV L AT FDYPT LAD L L +A A T R DEPIAIV M CR+PG Sbjct: 1753 TGVRLPATLVFDYPTSLALADFLGGELLGGQEAAAAPTAFT-ARDDEPIAIVAMSCRFPG 1811 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV SP LW LV G D I + P DRGWD+E LFDPDPD G +Y+R GGF+ D FDP Sbjct: 1812 GVRSPEDLWGLVLDGRDAISDMPDDRGWDVEGLFDPDPDRPGTSYSRAGGFLHDAHHFDP 1871 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ 1249 FFGISP EALA DPQQRLLLETSWEA E AGIDP +RGS TGVF G+ + YG + Sbjct: 1872 TFFGISPREALATDPQQRLLLETSWEAFERAGIDPATVRGSRTGVFAGVMYNDYGTLLHR 1931 Query: 1250 A----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 A + Y T SVASGR+SY GL GPA++VDTACSSSLV LHLA +LR GECDL Sbjct: 1932 APEGLEGYMGTSSSGSVASGRVSYTFGLEGPAVTVDTACSSSLVTLHLAVQALRNGECDL 1991 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV+ATP F+ FSRQRGLA+DGRCK FA AADGT + EG GML+++RLSDAR Sbjct: 1992 ALAGGVTVMATPGTFVAFSRQRGLASDGRCKPFAAAADGTAWGEGVGMLLVERLSDARAK 2051 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSA+NQDGASNGLTAP+GP+QQRVI AL+ AG++ ADVDVVEAHGTGT L Sbjct: 2052 GHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSAADVDVVEAHGTGTTL 2111 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIEAQALLATYG++HT D+PLWLGSIKSN GH+QAAAGVAG+IKMV+AM H ++P TL Sbjct: 2112 GDPIEAQALLATYGQEHTDDSPLWLGSIKSNFGHTQAAAGVAGIIKMVQAMHHGVVPKTL 2171 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH---------XXX 1536 H+D+PS HVDWS G V LLTE WP GRPRRA +SSFG+SGTNAH Sbjct: 2172 HVDEPSPHVDWSAGAVSLLTEQMAWPE-TGRPRRAAISSFGISGTNAHTIIEQAPEEFAP 2230 Query: 1537 XXXXXXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELD---AGDVGYSL 1593 G VL +V+SA++A + QA RL V A E+ A DV YSL Sbjct: 2231 VRPVRVIEPEAVGAGSRVLPFVLSAKSAGALRGQAVRLKAHVEASPEVSGAGAADVAYSL 2290 Query: 1594 VTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWL 1653 T R++F+HRAVVV R+ELL LA V GV G A GGK F+F GQG+Q L Sbjct: 2291 ATRRAVFDHRAVVVAGDREELLRALAAVESEGTAAGVTRGTA-GGGKLAFLFTGQGSQRL 2349 Query: 1654 GMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVA 1713 GMGREL YP L+ PL++ ++GADA LL+ T + QPALFAVEVA Sbjct: 2350 GMGRELYETYPVFARALDAACAGLE----LPLKDALFGADAGLLDETAYTQPALFAVEVA 2405 Query: 1714 LYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAV 1773 L+RLLESWG+RP + GHS+GE++AAHV+G RGRLMQALP GGVM AV Sbjct: 2406 LFRLLESWGVRPDFLAGHSIGEIAAAHVAGVLSLDDACALVAARGRLMQALPTGGVMIAV 2465 Query: 1774 QAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHS 1833 QA E E+ PLL ++VS+AA+NGP SVV++G +V+ + GR+ +RL VSHAFHS Sbjct: 2466 QASEDEVLPLLTDRVSIAAINGPQSVVIAGDEADAVAIVESFS--GRKSKRLTVSHAFHS 2523 Query: 1834 VLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVC 1893 M+ ML FR VA+ + P IPV+SN+TG LV ++ GSAD+WVRH+REAVRF D + Sbjct: 2524 PHMDGMLAGFRKVAESLSYEAPRIPVVSNLTGALVTDEMGSADFWVRHVREAVRFLDGIR 2583 Query: 1894 FAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXX 1953 +AG T +VE+GP G L++L +E + P LRK RPE Sbjct: 2584 ALEAAGVTAYVELGPDGVLSALAQECVTGEGAAFAPALRKGRPEAETITTALALAHNHGT 2643 Query: 1954 XXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DW + +G G QRV LPTYAF ER+W+ Sbjct: 2644 SVDWETYFSGTGAQRVDLPTYAFQRERYWI 2673 Score = 918 bits (2373), Expect = 0.0 Identities = 489/901 (54%), Positives = 593/901 (65%), Gaps = 40/901 (4%) Query: 1116 EPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYT 1175 EPIAIVGM CRYPG V SP LW+LV+ D I FP DRGWD+ RLFD DPD G +Y Sbjct: 33 EPIAIVGMSCRYPGDVESPEDLWRLVSEETDAISPFPTDRGWDMGRLFDADPDGRGTSYV 92 Query: 1176 RHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVF 1235 + GGF+ FDP FFGISP EA+AMDPQQRLLLETSWEA E AGIDP +LRGS TGVF Sbjct: 93 QEGGFLHSANRFDPAFFGISPREAVAMDPQQRLLLETSWEAFERAGIDPTSLRGSRTGVF 152 Query: 1236 VGI----YGDGYGLGTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 G+ Y + + Y TG +S+ASGR+SY GL GPA++VDTACSSSLV L Sbjct: 153 AGVMYHDYASRLRAVPEEVEGYLGTGGSSSIASGRVSYTFGLEGPALTVDTACSSSLVTL 212 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 HLA +LR GEC LALAGG TV+ATP F FSRQRGL+ DGRCK+FAD+ADGTG++EGA Sbjct: 213 HLAMQALRKGECSLALAGGVTVMATPGTFTEFSRQRGLSFDGRCKSFADSADGTGWAEGA 272 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 GML+++RLSDAR+ G VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+DA +T A Sbjct: 273 GMLLVERLSDARKNGHTVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLTAA 332 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 DVDVVEAHGTGT LGDPIEAQALLATYGR+HT D+PLWLGS+KSN+GH+QAAAGVAG+IK Sbjct: 333 DVDVVEAHGTGTTLGDPIEAQALLATYGREHTEDSPLWLGSVKSNLGHTQAAAGVAGIIK 392 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV A+RH +P TLH+D+PS +VDWS G V LL E+ EWP GRPRRA +SSFG+SGTN Sbjct: 393 MVMAIRHGRIPKTLHVDEPSTNVDWSAGAVSLLRESVEWPE-TGRPRRAAISSFGISGTN 451 Query: 1532 AHXXXXXXXXXXXXXXXXXG-----------------------------PGVLAWVVSAR 1562 AH P VL W VSAR Sbjct: 452 AHTIIEQAPLPEAETETEPTGDETDGSESTAGAEGTEGTEGAGVRPVSVPPVLPWPVSAR 511 Query: 1563 TAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVV 1622 T + AQA RLL VR + V SL T R+ EHRAVVV R+ LA LA + Sbjct: 512 TEEALHAQAERLLAHVRTNPDQAPVGVALSLATGRAALEHRAVVVATDRETALADLAALA 571 Query: 1623 EGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLA 1682 G V G GKT F+F GQG+Q LGMGREL YP L+ Sbjct: 572 SGETSARVVLGEPGARGKTAFLFTGQGSQRLGMGRELYEEYPVFADALDAVCARLE---- 627 Query: 1683 RPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVS 1742 PL++V++GADA LL+ T + QPALFAVEVAL+RL+ESWG++P + GHS+GE++AAHV+ Sbjct: 628 LPLKDVLFGADARLLDETAYTQPALFAVEVALFRLVESWGLKPDFLAGHSIGEIAAAHVA 687 Query: 1743 GXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLS 1802 G RGRLM ALP GGVM AVQA E E+ PLL +VS+AA+NGP SVV++ Sbjct: 688 GVFSLEDACALVSARGRLMGALPAGGVMIAVQASEDEVLPLLTARVSIAAINGPQSVVIA 747 Query: 1803 GAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISN 1862 G +V+ GR+ +RL VSHAFHS M+ MLE FR VA+ + P IPV+SN Sbjct: 748 GDEADAVAIVESFT--GRKSKRLTVSHAFHSPHMDGMLEDFRVVAEGLSYEAPRIPVVSN 805 Query: 1863 VTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQ 1922 +TG LV+++ GSAD+WVRH+REAVRF D + +AG T +VE+GP G L+++ + + Sbjct: 806 LTGALVSDEMGSADFWVRHVREAVRFLDGIRALEAAGVTTYVELGPDGVLSAMAQACVTG 865 Query: 1923 VSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 + V VP LR R E DW + AG G +RV LPTYAF + +W Sbjct: 866 ENSVFVPVLRSGRSEAESVTTALAQAHVRGIAVDWQAYFAGTGAERVDLPTYAFQRDHYW 925 Query: 1983 L 1983 L Sbjct: 926 L 926 Score = 708 bits (1827), Expect = 0.0 Identities = 420/982 (42%), Positives = 559/982 (56%), Gaps = 33/982 (3%) Query: 10 ALQEWFTHYIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWD 68 A+ E +AA G E V+ ++G S+ + + L G+ +P V+D Sbjct: 1705 AVMELVRAQVAAVLGLAGPEAVDPARSFSEVGFDSLTAVELRNRLGAATGVRLPATLVFD 1764 Query: 69 NPSAHDVIKSVLGGD--GSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPL 126 P++ + LGG+ G Q +A + T + EPIA++ M+CRF G V L Sbjct: 1765 YPTSL-ALADFLGGELLGGQEAAAAPTAFTARDD----EPIAIVAMSCRFPGGVRSPEDL 1819 Query: 127 WDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETIY---GCFLEDVEGFDNKFFDIPPD 181 W + + + AI++ P R D D T Y G FL D FD FF I P Sbjct: 1820 WGLVLDGRDAISDMPDDRGWDVEGLFDPDPDRPGTSYSRAGGFLHDAHHFDPTFFGISPR 1879 Query: 182 EAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIW 241 EA DPQQRLLLETSW A E AGI P T++ S TGVF GV DY LL + Sbjct: 1880 EALATDPQQRLLLETSWEAFERAGIDPATVRGSRTGVFAGVMYNDYGTLLHRAPEGLEGY 1939 Query: 242 DNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNV 301 T S S+ + R+SY + GP++ +DTACSSSLV HLA ++L +GECDLA+ G V Sbjct: 1940 MGTSSSGSVASGRVSYTFGLEGPAVTVDTACSSSLVTLHLAVQALRNGECDLALAGGVTV 1999 Query: 302 LISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVL 361 + +P + F ++ G C+ F A ADG GEG G++++ERLSDAR G VLAV+ Sbjct: 2000 MATPGTFVAFSRQRGLASDGRCKPFAAAADGTAWGEGVGMLLVERLSDARAKGHPVLAVV 2059 Query: 362 TGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHA 421 GSA+NQDG SNG+ APN +Q V+ A A + A++D VEAHGTGT++GD IEA A Sbjct: 2060 RGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSAADVDVVEAHGTGTTLGDPIEAQA 2119 Query: 422 LGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPN 481 L +G+ PL +GSIK N GH + AAG+AG+IK V + G + + + P+P+ Sbjct: 2120 LLATYGQEHTDDSPLWLGSIKSNFGHTQAAAGVAGIIKMVQAMHHGVVPKTLHVDEPSPH 2179 Query: 482 IPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH---------XXXXXXXXXXX 532 + ++ ++++ E WP GRPRRA +SSFG GTNAH Sbjct: 2180 VDWSAGAVSLLTEQMAWPE-TGRPRRAAISSFGISGTNAHTIIEQAPEEFAPVRPVRVIE 2238 Query: 533 XXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELD---AGDVGYSLVTTRSLFE 589 G VL +V+SA++A + QA RL V A E+ A DV YSL T R++F+ Sbjct: 2239 PEAVGAGSRVLPFVLSAKSAGALRGQAVRLKAHVEASPEVSGAGAADVAYSLATRRAVFD 2298 Query: 590 HRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCA 649 HRAVVV R+ELL LA V GV G A GGK F+F GQG+Q LGMGREL Sbjct: 2299 HRAVVVAGDREELLRALAAVESEGTAAGVTRGTA-GGGKLAFLFTGQGSQRLGMGRELYE 2357 Query: 650 GYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESW 709 YP L+ PL++ ++GADA LL+ T + QPALFAVEVAL+RLLESW Sbjct: 2358 TYPVFARALDAACAGLE----LPLKDALFGADAGLLDETAYTQPALFAVEVALFRLLESW 2413 Query: 710 GMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELR 769 G+RP + GHS+GE++AAHV+G RGRLMQALP GGVM AVQA E E+ Sbjct: 2414 GVRPDFLAGHSIGEIAAAHVAGVLSLDDACALVAARGRLMQALPTGGVMIAVQASEDEVL 2473 Query: 770 PLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLE 829 PLL ++VS+AA+NGP SVV++G +V+ + GR+ +RL VSHAFHS M+ ML Sbjct: 2474 PLLTDRVSIAAINGPQSVVIAGDEADAVAIVESFS--GRKSKRLTVSHAFHSPHMDGMLA 2531 Query: 830 QFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGAT 889 FR VA+ + P IPV+SN+TG LV ++ GSAD+WVRH+REAVRF D + +AG T Sbjct: 2532 GFRKVAESLSYEAPRIPVVSNLTGALVTDEMGSADFWVRHVREAVRFLDGIRALEAAGVT 2591 Query: 890 RFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVL 949 +VE+GP G L++L +E + P LRK RPE DW + Sbjct: 2592 AYVELGPDGVLSALAQECVTGEGAAFAPALRKGRPEAETITTALALAHNHGTSVDWETYF 2651 Query: 950 AGCGGQRVGLPTYAFAHERFWL 971 +G G QRV LPTYAF ER+W+ Sbjct: 2652 SGTGAQRVDLPTYAFQRERYWI 2673 Score = 690 bits (1780), Expect = 0.0 Identities = 398/902 (44%), Positives = 521/902 (57%), Gaps = 43/902 (4%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARR---LGAAAADWLGDEQETIY 161 EPIA++GM+CR+ G V LW ++E+ AI+ +P R +G D D + T Y Sbjct: 33 EPIAIVGMSCRYPGDVESPEDLWRLVSEETDAISPFPTDRGWDMGRLF-DADPDGRGTSY 91 Query: 162 ---GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGV 218 G FL FD FF I P EA MDPQQRLLLETSW A E AGI P +L+ S TGV Sbjct: 92 VQEGGFLHSANRFDPAFFGISPREAVAMDPQQRLLLETSWEAFERAGIDPTSLRGSRTGV 151 Query: 219 FVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVA 278 F GV DY L + + TGGSSSI + R+SY + GP+L +DTACSSSLV Sbjct: 152 FAGVMYHDYASRLRAVPEEVEGYLGTGGSSSIASGRVSYTFGLEGPALTVDTACSSSLVT 211 Query: 279 AHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEG 338 HLA ++L GEC LA+ G V+ +P + F +S G C++F ADG EG Sbjct: 212 LHLAMQALRKGECSLALAGGVTVMATPGTFTEFSRQRGLSFDGRCKSFADSADGTGWAEG 271 Query: 339 CGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDP 398 G++++ERLSDAR+ G TVLAV+ GSAVNQDG SNG+ APN +Q V+ A A + Sbjct: 272 AGMLLVERLSDARKNGHTVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALADARLTA 331 Query: 399 AEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLI 458 A++D VEAHGTGT++GD IEA AL +GR PL +GS+K N+GH + AAG+AG+I Sbjct: 332 ADVDVVEAHGTGTTLGDPIEAQALLATYGREHTEDSPLWLGSVKSNLGHTQAAAGVAGII 391 Query: 459 KTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGT 518 K V+ ++ G++ + + P+ N+ ++ ++++ E EWP GRPRRA +SSFG GT Sbjct: 392 KMVMAIRHGRIPKTLHVDEPSTNVDWSAGAVSLLRESVEWPET-GRPRRAAISSFGISGT 450 Query: 519 NAHXXXXXXXXXXXXXXXXXG-----------------------------PGVLAWVVSA 549 NAH P VL W VSA Sbjct: 451 NAHTIIEQAPLPEAETETEPTGDETDGSESTAGAEGTEGTEGAGVRPVSVPPVLPWPVSA 510 Query: 550 RTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEV 609 RT + AQA RLL VR + V SL T R+ EHRAVVV R+ LA LA + Sbjct: 511 RTEEALHAQAERLLAHVRTNPDQAPVGVALSLATGRAALEHRAVVVATDRETALADLAAL 570 Query: 610 VEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHL 669 G V G GKT F+F GQG+Q LGMGREL YP L+ Sbjct: 571 ASGETSARVVLGEPGARGKTAFLFTGQGSQRLGMGRELYEEYPVFADALDAVCARLEL-- 628 Query: 670 ARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHV 729 PL++V++GADA LL+ T + QPALFAVEVAL+RL+ESWG++P + GHS+GE++AAHV Sbjct: 629 --PLKDVLFGADARLLDETAYTQPALFAVEVALFRLVESWGLKPDFLAGHSIGEIAAAHV 686 Query: 730 SGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVL 789 +G RGRLM ALP GGVM AVQA E E+ PLL +VS+AA+NGP SVV+ Sbjct: 687 AGVFSLEDACALVSARGRLMGALPAGGVMIAVQASEDEVLPLLTARVSIAAINGPQSVVI 746 Query: 790 SGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVIS 849 +G +V+ GR+ +RL VSHAFHS M+ MLE FR VA+ + P IPV+S Sbjct: 747 AGDEADAVAIVESFT--GRKSKRLTVSHAFHSPHMDGMLEDFRVVAEGLSYEAPRIPVVS 804 Query: 850 NVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLA 909 N+TG LV+++ GSAD+WVRH+REAVRF D + +AG T +VE+GP G L+++ + + Sbjct: 805 NLTGALVSDEMGSADFWVRHVREAVRFLDGIRALEAAGVTTYVELGPDGVLSAMAQACVT 864 Query: 910 QVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERF 969 + V VP LR R E DW + AG G +RV LPTYAF + + Sbjct: 865 GENSVFVPVLRSGRSEAESVTTALAQAHVRGIAVDWQAYFAGTGAERVDLPTYAFQRDHY 924 Query: 970 WL 971 WL Sbjct: 925 WL 926 Score = 145 bits (365), Expect = 9e-32 Identities = 118/399 (29%), Positives = 178/399 (44%), Gaps = 36/399 (9%) Query: 2023 LQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLT 2082 L GL EQ+ +L +V AAVL + Q F + GL SL+AVELRN+L T Sbjct: 3492 LSGLPQDEQERVLLDLVRAQVAAVLAYPSPDAVGESQEFLELGLDSLTAVELRNQLNAAT 3551 Query: 2083 GVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPE-------LDRVDALTDLFLQTCD 2135 G+ L AT FD+PTP +A+ L + L + A E + + Sbjct: 3552 GLRLPATLLFDHPTPALVAERLRAELAGASGPAAVREGAADSGAEGSAGVFGAMLHEAGT 3611 Query: 2136 AGRDDDGWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDVAVVCLPTLTVLSSPHAY 2195 G +++ A+ R + R+ +V L+ G + +VC ++ +S PH Y Sbjct: 3612 QGASGQFMELLMQASRFRPSFASAAELRKAPSLVRLSRGDTRPGLVCFSSILSISGPHQY 3671 Query: 2196 LDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGAAQAILHAVGDHPHLVLAGYSSG 2255 A A GR VHAL PGF + LP + V+E A+A+L P VL G+SSG Sbjct: 3672 ARFASAFRGRRDVHALGAPGFLRGEQLPSATDAVIEAQAEAVLRHADGAP-FVLLGHSSG 3730 Query: 2256 GVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVNADNPDQVGVNETGALFSRRVTSMAR 2315 G+LAHA+ L E P + +ID Y S +A Q G++E + R+ T + Sbjct: 3731 GMLAHAVAGRL-ESEGVFPQALVMIDIY--SHDDDAIIGIQPGLSE--GMDERQDTYVPV 3785 Query: 2316 ELDQLNXXXXXXXXXXXXXFGTWEPVVSAVPLLNMIAMDETAACERVRAERINRWRVATA 2375 + ++L FG W+P V P L + A ER W +T Sbjct: 3786 DDNRL-----LAMGAYFRLFGGWKPEVVKTPTLLVRA-----------GERFFDWTRSTD 3829 Query: 2376 -------EASYSVVEVPGDHFDMITTSSDATTTALHGWI 2407 + ++ ++VPG+HF M+ + T A+ GW+ Sbjct: 3830 GDWRSYWDLDHTALDVPGNHFTMMEEHAPTTAQAVEGWL 3868 Score = 80.1 bits (196), Expect = 4e-12 Identities = 52/128 (40%), Positives = 66/128 (51%), Gaps = 14/128 (10%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 +L GL+ ++ AAV+ +V AAVLG G +D ++FS+ G SL+AVELRNRL Sbjct: 1693 KLAGLAVDQRSAAVMELVRAQVAAVLGLAGPEAVDPARSFSEVGFDSLTAVELRNRLGAA 1752 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 TGV L AT FDYPT LAD L L A P T RDD+ Sbjct: 1753 TGVRLPATLVFDYPTSLALADFLGGELLGGQEAAAAP--------------TAFTARDDE 1798 Query: 2142 GWQIVALA 2149 IVA++ Sbjct: 1799 PIAIVAMS 1806 Score = 67.8 bits (164), Expect = 2e-08 Identities = 41/96 (42%), Positives = 53/96 (55%), Gaps = 2/96 (2%) Query: 1011 LQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLT 1070 L GL EQ+ +L +V AAVL + Q F + GL SL+AVELRN+L T Sbjct: 3492 LSGLPQDEQERVLLDLVRAQVAAVLAYPSPDAVGESQEFLELGLDSLTAVELRNQLNAAT 3551 Query: 1071 GVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAA 1106 G+ L AT FD+PTP +A+ L + L S PAA Sbjct: 3552 GLRLPATLLFDHPTPALVAERLRAEL--AGASGPAA 3585 >tr|B4VBW0|B4VBW0_9ACTO Tax_Id=465541 SubName: Full=Polyketide synthase type I; Flags: Fragment;[Streptomyces sp. Mg1] Length = 10873 Score = 1013 bits (2619), Expect = 0.0 Identities = 538/984 (54%), Positives = 667/984 (67%), Gaps = 15/984 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 R GL+ E + +L +V H AAVLG +GA + A +AF + G SL+AVELRNRL Sbjct: 6441 RFAGLAAVELERELLGLVRTHVAAVLGHEGAETVGAERAFKELGFDSLTAVELRNRLGAA 6500 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL-HHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYP 1128 TGV+L AT FDYPT + + L L Q R A + D+PIAIV M CR+P Sbjct: 6501 TGVSLPATLIFDYPTASAITAFLRDELLGTQARIAGPVSTAVTPVDDDPIAIVAMSCRFP 6560 Query: 1129 GGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFD 1188 GGV +P LWQL+A+GGD IGEFP DRGWD++RL++PDPD G Y R GGF+ D ADFD Sbjct: 6561 GGVRTPEDLWQLLAAGGDAIGEFPVDRGWDLDRLYNPDPDQQGTFYAREGGFLYDAADFD 6620 Query: 1189 PGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS 1248 FFGISP EALAMDPQQRLLLET+WE E AGIDP A+RGS GVF+G G Y Sbjct: 6621 ADFFGISPREALAMDPQQRLLLETTWETFERAGIDPAAVRGSQAGVFIGTNGQDYDATFH 6680 Query: 1249 QA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 + + TG+ SV SGR+SY GL GPA++VDTACS+SLVALH A +LR GECD Sbjct: 6681 SVPDGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAIQALRGGECD 6740 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 +ALAGG TV+++P +I FSRQRGLA DGR KAF+ ADGTG+ EG GML+++RLSDA+R Sbjct: 6741 MALAGGVTVMSSPGAYIDFSRQRGLAEDGRIKAFSADADGTGWGEGVGMLLVERLSDAQR 6800 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 G PVLA++ GSA+NQDGASNGLTAP+GP+QQRVI AAL+ AG++ A+VD VEAHGTGTR Sbjct: 6801 NGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRAALASAGLSAAEVDAVEAHGTGTR 6860 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG++ + PL LGSIKSN+GH+QAAAGVAGVIKMV AM+H +LP T Sbjct: 6861 LGDPIEAQALLATYGQERAEEQPLLLGSIKSNIGHTQAAAGVAGVIKMVLAMQHGVLPQT 6920 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+++P+ HVDWS G V LLTE R+WP GRPRRAG+SSFG SGTNAH Sbjct: 6921 LHVNEPTPHVDWSAGEVALLTEQRDWPE-TGRPRRAGISSFGFSGTNAHTIIEQAPDVLD 6979 Query: 1545 XXXXXXGP----GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLF 1600 GVL WV+SA+ A + QA RLL V + L+ DV YSL T+RS Sbjct: 6980 VEPSVQPQERPGGVLPWVLSAKNEAALRVQAERLLAAVTSDELLEPADVAYSLATSRSAL 7039 Query: 1601 EHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELC 1660 E RAVVV RDE LA L + G GVA G A GG T F+F GQG+Q LGMGREL Sbjct: 7040 ERRAVVVAGERDEFLAALRALAAGEQTAGVAHGTAAVGG-TAFLFTGQGSQRLGMGRELY 7098 Query: 1661 AGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLES 1720 +P +D HL PL+EV++G+DA +L+ TE+ QPALFAVEVAL+RL+ES Sbjct: 7099 DAHPVFADALDAICARMDGHLELPLKEVLFGSDAAVLDRTEYTQPALFAVEVALFRLVES 7158 Query: 1721 WGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQEL 1780 WG+RP + GHS+GE++AAHV+G RGRLMQALP GGVM AV+A E+E+ Sbjct: 7159 WGIRPDFLSGHSIGEIAAAHVAGVLSLDDACALVAARGRLMQALPSGGVMIAVEASEEEV 7218 Query: 1781 RPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPML 1840 PLL ++VS+AAVNGP SVV++G +A + + A R+ +RL VSHAFHS M+ ML Sbjct: 7219 LPLLTDRVSIAAVNGPRSVVIAGDEDAAVALAESFA--DRKSKRLTVSHAFHSPHMDGML 7276 Query: 1841 EQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGA 1900 E FR V + P IPV+SN+TG LV ++ GSA++WVRH+REAVRF D + +AG Sbjct: 7277 EDFRQVVAGLSFEAPRIPVVSNLTGALVTDEMGSAEFWVRHVREAVRFLDGIRVLEAAGV 7336 Query: 1901 TRFVEVGPAGGLTSLIEESLA--QVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWA 1958 T +VE+GP G L++L + LA + + +P LRK RPE DW+ Sbjct: 7337 TAYVELGPDGVLSALAQGCLADENSNALFMPALRKGRPEAETLVTTLGQAHAHGVEVDWS 7396 Query: 1959 SVLAGCGGQRVGLPTYAFAHERFW 1982 + AG G +RV LPTYAF +RFW Sbjct: 7397 AYFAGSGARRVDLPTYAFQRQRFW 7420 Score = 1010 bits (2612), Expect = 0.0 Identities = 537/985 (54%), Positives = 664/985 (67%), Gaps = 17/985 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 R GL E + +L +V H AAVLG +GA + A +AF + G SL+AVELRNRL Sbjct: 9737 RFAGLGAVELERELLGLVRTHVAAVLGHEGAETVGAERAFKELGFDSLTAVELRNRLGAA 9796 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TGV+L AT FDYPT + + L L A V D+PIAIV M CR+PG Sbjct: 9797 TGVSLPATLIFDYPTASAITAFLRDELLGSEVQMTAPVVTAVA--DDPIAIVAMSCRFPG 9854 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV +P LWQL+A+GGD IGEFP DRGWD++RL+ PDPD G Y R GGF+ D ADFD Sbjct: 9855 GVRTPEDLWQLLAAGGDAIGEFPVDRGWDLDRLYSPDPDRQGTFYAREGGFLYDAADFDA 9914 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ 1249 FFGISP EALAMDPQQRLLLET+WEA E AGI P ++RGS GVF+G G YG T Q Sbjct: 9915 VFFGISPREALAMDPQQRLLLETTWEAFERAGIAPSSVRGSQAGVFIGTNGQDYG-ATLQ 9973 Query: 1250 A-----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 A + + TG+ SV SGR+SY GL GPA++VDTACS+SLVALH A +LR GECD Sbjct: 9974 ALPDGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAIQALRNGECD 10033 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 +ALAGG TV+++P +I FSRQRGLA DGR KAF+D ADGTG+ EG GML+++RLSDARR Sbjct: 10034 MALAGGVTVMSSPGAYIDFSRQRGLAADGRIKAFSDDADGTGWGEGVGMLLVERLSDARR 10093 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 G PVLA++ GSA+NQDGASNGLTAP+GP+QQRVI AAL+ AG++ ++VD VEAHGTGTR Sbjct: 10094 NGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRAALASAGLSSSEVDAVEAHGTGTR 10153 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG++ D PL LGSIKSN+GH+QAAAGVAGV+KMV AM+H +LP T Sbjct: 10154 LGDPIEAQALLATYGQERPADQPLLLGSIKSNIGHTQAAAGVAGVMKMVLAMQHGVLPQT 10213 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+++ + HVDWS G V LLTE + WP GRPRRAG+SSFG SGTNAH Sbjct: 10214 LHVNEATPHVDWSAGEVALLTERQAWPE-TGRPRRAGISSFGFSGTNAHTIVEQAPDDIR 10272 Query: 1545 XXXXXXG----PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLF 1600 PGV+ WV+S + A + AQA RLL V + L+ DV YSL T+RS Sbjct: 10273 EAASPVAPQQRPGVVPWVLSGKNEAALRAQAERLLAAVTSDELLEPADVAYSLATSRSAL 10332 Query: 1601 EHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELC 1660 E RAVVV RDE LA L + G GVA G + G + F+F GQG+Q LGMGREL Sbjct: 10333 ERRAVVVAGERDEFLAALRALAAGEQAAGVAHG-TVSAGASAFLFTGQGSQRLGMGRELY 10391 Query: 1661 AGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLES 1720 +P +D HL PL+EV++G+DA LL+ T F QPALFA+EVAL+RLLES Sbjct: 10392 DAFPVFADALDAICARMDGHLELPLKEVLFGSDAALLDETRFTQPALFAIEVALFRLLES 10451 Query: 1721 WGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQEL 1780 WG+RP + GHS+GE++AAHV+G RGRLMQALP GGVM AVQA E+E+ Sbjct: 10452 WGVRPDFLSGHSIGEIAAAHVAGVFSLDDACALVAARGRLMQALPAGGVMIAVQASEEEV 10511 Query: 1781 RPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPML 1840 PLL ++VS+AAVNGP +VV++G +A + V A R+ +RL VSHAFHS M+ ML Sbjct: 10512 LPLLTDRVSIAAVNGPEAVVVAGDEDAATAVA--AAFPDRKSKRLTVSHAFHSPHMDGML 10569 Query: 1841 EQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGA 1900 FR VA+ + P IPV+SN+TG LV ++ SAD+WVRH+REAVRF D + +AG Sbjct: 10570 ADFRKVAESLSYESPRIPVVSNLTGALVTDEMASADFWVRHVREAVRFLDGIRVLEAAGV 10629 Query: 1901 TRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASV 1960 T FVE+GP G L++L ++ Q + VP LRK RPE DW + Sbjct: 10630 TTFVELGPDGVLSALAQDCTEQ-DALFVPALRKGRPEAEAVVTALARAHVHGVTVDWTAF 10688 Query: 1961 LAGCGGQRVGLPTYAFAHERFWLAD 1985 +G +RV LPTYAF +R+WL + Sbjct: 10689 YSGTAARRVDLPTYAFQRKRYWLEE 10713 Score = 1009 bits (2609), Expect = 0.0 Identities = 552/995 (55%), Positives = 663/995 (66%), Gaps = 28/995 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L AE + +L +VC AAVLG GA +DA +AF D G SL+AVELRN LK Sbjct: 4924 RLLALPVAEHEGVLLDLVCGRVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKAE 4983 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRI-----DEPIAIVGMG 1124 TG+ L T FDYPTP LA HLL+ L VR VR D+PI IVGMG Sbjct: 4984 TGLRLPPTLIFDYPTPVALARHLLAELAVTGDLEVQDGVRVPVRAAVDVTDDPIVIVGMG 5043 Query: 1125 CRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDV 1184 CRYPGGV SP +LWQLVA+GGD + FP DRGW++E L+ PDPD G +YTR GGF+ DV Sbjct: 5044 CRYPGGVRSPEELWQLVATGGDGVTTFPSDRGWNVEALYHPDPDHAGTSYTREGGFLHDV 5103 Query: 1185 ADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGI----YG 1240 ADFDP FFGISP EALAMDPQQRLLLETSWEA E AGIDP LRGS TGVF G+ Y Sbjct: 5104 ADFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGVMYHDYV 5163 Query: 1241 DGYGLGTSQA---------QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 G+GLG + Y TG+ S+ASGRI+Y GL GPA++VDTACSSSLVAL Sbjct: 5164 TGFGLGDGAGSGDALPEGVEGYLGTGNAGSIASGRIAYTFGLEGPAVTVDTACSSSLVAL 5223 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 H A +LR GECD+ALAGG V+ATP F+ FSRQRGL+ DGRCK+FA AADGTG++EGA Sbjct: 5224 HWAIQALRGGECDMALAGGVAVMATPETFVDFSRQRGLSADGRCKSFAAAADGTGWAEGA 5283 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 GML+++R SDA R G P+LA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+ AG++ Sbjct: 5284 GMLLVERQSDALRNGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIREALASAGLSAV 5343 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 DVD VEAHGTGTRLGDPIEAQALLATYG+D PL LGSIKSN+GH+QAAAGVAG+IK Sbjct: 5344 DVDAVEAHGTGTRLGDPIEAQALLATYGQDRPEGRPLLLGSIKSNIGHTQAAAGVAGIIK 5403 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV AMRH +LP TLH+D PS V+W G V LLT+A +WP GRPRRAG+SSFG+SGTN Sbjct: 5404 MVMAMRHGVLPQTLHVDAPSTQVEWEAGDVSLLTQAMDWPQ-TGRPRRAGISSFGISGTN 5462 Query: 1532 AHXXXXXXXXXXXXXXXXXG--PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDV 1589 AH P V WV+SA+ + AQA +L V + DV Sbjct: 5463 AHTIIEQPPVLERAEPEAAALLPAV-PWVLSAKGEDALRAQARQLHSHVASTPGARPVDV 5521 Query: 1590 GYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQG 1649 +SL R+ FE RA VV A R+ LLAGLA + EGR + G + GK F+F GQG Sbjct: 5522 AWSLAANRASFEDRAAVVAADREGLLAGLAALAEGRSTATLVEGSPV-AGKLAFLFTGQG 5580 Query: 1650 AQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFA 1709 +Q LGMGREL YP LD L PL+EV++G D E+L+ TEF QPALFA Sbjct: 5581 SQRLGMGRELYEAYPVFAAALDAVCERLDLEL--PLKEVLFGNDREVLDRTEFTQPALFA 5638 Query: 1710 VEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGV 1769 VEVAL+RLLESWG+R + GHSVGE++AAHV+G RGRLMQALP GGV Sbjct: 5639 VEVALFRLLESWGVRADFLSGHSVGEIAAAHVAGVFSLDDACALVAARGRLMQALPEGGV 5698 Query: 1770 MYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSH 1829 M AVQA E E+ PLL E+VS+AA+NGP SVV++G +A V A R+ +RL VSH Sbjct: 5699 MIAVQASEDEVLPLLTERVSIAAINGPRSVVVAGDEDAALAVA--AAFPDRKSKRLTVSH 5756 Query: 1830 AFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFA 1889 AFHS M+ ML+ FR V + + P IP++SN+TG L+A++ GSA++WVRH+REAVRF Sbjct: 5757 AFHSPHMDGMLDDFRRVVEGLSFQAPRIPLVSNLTGALIADEMGSAEFWVRHVREAVRFL 5816 Query: 1890 DSVCFAHSAGATRFVEVGPAGGLTSLIEESLA-QVSVVAVPTLRKDRPEPFXXXXXXXXX 1948 D V AG T FVE+GP G L++L ++ LA V VP LR R E Sbjct: 5817 DGVRALEGAGVTSFVELGPDGVLSALAQDCLAGDADVAFVPVLRAGRGEAETLVTAVAQA 5876 Query: 1949 XXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DW++ AG G + V LPTYAF +R+WL Sbjct: 5877 HVRGVEVDWSAFFAGTGARSVELPTYAFQRQRYWL 5911 Score = 994 bits (2569), Expect = 0.0 Identities = 534/985 (54%), Positives = 659/985 (66%), Gaps = 16/985 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 +L L AEQ +L +V H AAVLG DGA + A +AF + G SL+AV+LRNRL Sbjct: 1620 KLAELPRAEQDRELLGLVRTHVAAVLGHDGADAVGAERAFKELGFDSLTAVDLRNRLGAA 1679 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 T + L AT +DYPT + LA++L L A + D+PIAIV M CR+PG Sbjct: 1680 TALRLPATLVYDYPTSSALAEYLRGELMGNAPKADSPQHVAAATDDDPIAIVAMSCRFPG 1739 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV +P LW+L+A G D + +FP DRGWD++RL+D +P+ G +YTR GGF+ D A+FD Sbjct: 1740 GVRTPEDLWRLLAQGTDAVADFPADRGWDLDRLYDANPEQPGTSYTREGGFLYDAAEFDA 1799 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGY-GLGTS 1248 GFFGISP EALAMDPQQRLLLETSWEA E AGIDP L+GS GVFVG G Y L Sbjct: 1800 GFFGISPREALAMDPQQRLLLETSWEAFERAGIDPALLKGSQAGVFVGTNGQDYLTLVAG 1859 Query: 1249 QA---QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 +A + + TG+ SV SGR+SY GL GPAI+VDTACSSSLVALHLA +LR GEC + Sbjct: 1860 EADGLEGHVGTGNAASVVSGRLSYVFGLEGPAITVDTACSSSLVALHLAVQALRQGECSM 1919 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV++TP FI FSRQRGLA DGR KAFA ADGTG+ EG GML+++RLSDA+R Sbjct: 1920 ALAGGVTVMSTPDAFIDFSRQRGLAEDGRIKAFAAGADGTGWGEGVGMLLVERLSDAQRN 1979 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSA+NQDGASNGLTAP+GP+QQRVI AL+ AG++ A+VD VEAHGTGTRL Sbjct: 1980 GHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSAAEVDAVEAHGTGTRL 2039 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIEAQALLATYG++ PL LGS+KSN+GH+QAAAGVAG+IKMV AMRH +LP TL Sbjct: 2040 GDPIEAQALLATYGQERAEGLPLLLGSVKSNIGHTQAAAGVAGIIKMVMAMRHGVLPRTL 2099 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAH-----XXXXXXX 1540 H+D P+ HVDWS G V+LLTE R+WP GRPRRAGVSSFG+SGTNAH Sbjct: 2100 HVDAPTPHVDWSAGEVELLTEQRDWPE-TGRPRRAGVSSFGLSGTNAHTIIEQAPDADAD 2158 Query: 1541 XXXXXXXXXXGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLF 1600 L + V+ + AG+ AQA +L+ ++ + D+ YSL RS F Sbjct: 2159 EAPTAPAEGTATAALPFAVTGKNPAGLRAQAQQLVSWLAENPQAAPADIAYSLAAGRSAF 2218 Query: 1601 EHRAVVV--GAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRE 1658 E RAVVV A RD L AGL + G G+ G A GG F+F GQG+Q LGMGRE Sbjct: 2219 ETRAVVVPDAADRDALTAGLRALAAGEHATGLLRGTA-SGGGLAFLFTGQGSQRLGMGRE 2277 Query: 1659 LCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLL 1718 L YP +D HL PL +V++G+DA +L+ TE+ QPALFAVEVAL+RL Sbjct: 2278 LYDTYPVFADALDAVCARMDAHLELPLTDVLFGSDAAVLDRTEYTQPALFAVEVALFRLA 2337 Query: 1719 ESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQ 1778 ESWG++P V GHS+GE++AAHV+G RGRLMQALP GGVM AVQA E+ Sbjct: 2338 ESWGVKPDFVSGHSIGEIAAAHVAGVFSLDDACALVAARGRLMQALPEGGVMIAVQASEE 2397 Query: 1779 ELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEP 1838 E+ PLL E+VS+AAVNGP SVV++G +A V D A R+ +RL VSHAFHS M+ Sbjct: 2398 EVLPLLTERVSIAAVNGPRSVVVAGDEDAALAVAD--AFPDRKSKRLTVSHAFHSPHMDG 2455 Query: 1839 MLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSA 1898 ML+ FR V + + G PAIPV+SN+TG LVA++ GSA++WVRH+REAVRF D V A Sbjct: 2456 MLDDFRRVVEGLSFGAPAIPVVSNLTGALVADEMGSAEFWVRHVREAVRFLDGVRVLEGA 2515 Query: 1899 GATRFVEVGPAGGLTSLIEESL-AQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDW 1957 G T FVE+GP G L++L ++ L V VP LR R E DW Sbjct: 2516 GVTSFVELGPDGVLSALAQDCLTGDADVAFVPVLRAGRGEAETLVTAVAQAHARGVEVDW 2575 Query: 1958 ASVLAGCGGQRVGLPTYAFAHERFW 1982 ++ AG G + V LPTYAF +R+W Sbjct: 2576 SAFFAGTGARSVELPTYAFQRQRYW 2600 Score = 992 bits (2565), Expect = 0.0 Identities = 532/991 (53%), Positives = 661/991 (66%), Gaps = 23/991 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L AE + +L +VC AAVLG GA +DA +AF D G SL+AVELRN LKT Sbjct: 8215 RLLALPVAEHEGVLLDLVCGRVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKTE 8274 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAP---AAAVRTRVRI-----DEPIAIV 1121 TG+ L T FDYPTP LA HLLS L S + V T VR D+PI IV Sbjct: 8275 TGLRLPPTLIFDYPTPAALARHLLSELGVTGASGDQDGSRGVLTPVRAVVDVTDDPIVIV 8334 Query: 1122 GMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFV 1181 GMGCRYPGGV +P +LWQLVASGGD + FP DRGW++E L+ PDPD +G +YTR GGF+ Sbjct: 8335 GMGCRYPGGVRTPEELWQLVASGGDGVTAFPTDRGWNVEALYHPDPDHVGTSYTREGGFL 8394 Query: 1182 SDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGI--- 1238 DVA+FD FFGISP EALAMDPQQRLLLETSWEA E AGIDP LRGS TGVF G+ Sbjct: 8395 HDVAEFDAAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGVMYH 8454 Query: 1239 -YGDGYGLGTSQ---AQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLA 1294 Y GYG G + Y TG+ S+ASGR+SY GL GPA++VDTACSSSLVALH A Sbjct: 8455 DYATGYGNGEELPEGVEGYLGTGNSGSIASGRVSYAFGLEGPAVTVDTACSSSLVALHWA 8514 Query: 1295 ANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGML 1354 +LR GECD+ALAGG V+ATP F+ FSRQRGL+ DGRCK+FA AADGTG++EGAGML Sbjct: 8515 IQALRGGECDMALAGGVAVMATPETFVDFSRQRGLSADGRCKSFAAAADGTGWAEGAGML 8574 Query: 1355 VLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVD 1414 +++R SDA R G P+LA++ GSA+NQDGASNGLTAP+GP+QQRVI AL+ AG++ +DVD Sbjct: 8575 LVERQSDALRNGHPILAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSTSDVD 8634 Query: 1415 VVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVE 1474 VEAHGTGTRLGDPIEAQALLATYG+D PL LGSIKSN+GH+QAAAGVAG+IKM+ Sbjct: 8635 AVEAHGTGTRLGDPIEAQALLATYGQDRPEGLPLLLGSIKSNIGHTQAAAGVAGIIKMIM 8694 Query: 1475 AMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHX 1534 AMRH +LP TLH+D PS V+W G V LLTEA +WP GRPRRAGVSSFG+SGTNAH Sbjct: 8695 AMRHGVLPQTLHVDTPSTQVEWEAGDVSLLTEAMDWPE-TGRPRRAGVSSFGISGTNAHT 8753 Query: 1535 XXXXXXXXXXXXXXXXGP--GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYS 1592 V+ WV+SA+ + AQA L + A ++ DV +S Sbjct: 8754 IIEQPPVLERAEAPAATVPLPVVPWVLSAKGEDALRAQARELQAHLLAAPDVRPVDVAWS 8813 Query: 1593 LVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQW 1652 L R+ FE RA VV A R+ LLAGLA + EGR + G + GK F+F GQG+Q Sbjct: 8814 LAANRASFEDRAAVVAADREGLLAGLAALAEGRSTAALVEGSPV-AGKLAFLFTGQGSQR 8872 Query: 1653 LGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEV 1712 LGMGREL YP +L+ L PL++V++G +A LL+ T + QPALFAVEV Sbjct: 8873 LGMGRELYEAYPVFAAALDAVCEQLNLEL--PLKDVLFGTNAALLDETRYTQPALFAVEV 8930 Query: 1713 ALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYA 1772 AL+RL+ESWG+RP + GHS+GE++AAHV+G RGRLMQALP GGVM A Sbjct: 8931 ALFRLVESWGIRPDFLSGHSIGEIAAAHVAGVFSLEDACTLVAARGRLMQALPSGGVMIA 8990 Query: 1773 VQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFH 1832 V+A E E+ PLL ++VS+AAVNGP SVV++G + + + A R+ +RL VSHAFH Sbjct: 8991 VEASEDEVLPLLTDRVSIAAVNGPRSVVIAGDEDVAVALAESFA--DRKSKRLTVSHAFH 9048 Query: 1833 SVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSV 1892 S M+ ML++FR V + + P I ++SN+TG V ++ SA++WVRH+R+AVRF D + Sbjct: 9049 SPHMDGMLDEFRQVVEGLSFETPRIQIVSNLTGAPVTDEMASAEFWVRHVRDAVRFLDGI 9108 Query: 1893 CFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXX 1952 AG T ++E+GP G L+++ +E L VP +R RPE Sbjct: 9109 RALEDAGVTTYLELGPGGVLSAMGQECLTGEGAAFVPVMRNGRPETEAMVAAAALAHVRG 9168 Query: 1953 XXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 +W+ G + V LPTYAF +R+WL Sbjct: 9169 LKVNWSQFFVGSDARSVELPTYAFQRQRYWL 9199 Score = 976 bits (2524), Expect = 0.0 Identities = 527/989 (53%), Positives = 657/989 (66%), Gaps = 20/989 (2%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L+ AEQ +L +V H AAVLG DGA + A +AF + G SL+AVELRNRL Sbjct: 3146 RLAALAPAEQTRELLGLVRTHVAAVLGHDGADAVGAERAFKELGFDSLTAVELRNRLGAA 3205 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 T + L T +DYPT LADHL L + A +PIAIV M CR+PG Sbjct: 3206 TELRLPVTLIYDYPTSAALADHLREELVGSIPVSGALLPVAAAVDGDPIAIVAMSCRFPG 3265 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 G++SP LWQL+A G D + +FP DRGW+++RL+ PDPD G +YTRHGGFV+ A+FD Sbjct: 3266 GIASPEDLWQLLAQGTDAVADFPADRGWNLDRLYSPDPDQPGTSYTRHGGFVTGAAEFDA 3325 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQ 1249 FFGISP EALAMDPQQRLLLETSWEA E AGIDP +LRGS GVFVG G Y ++ Sbjct: 3326 DFFGISPREALAMDPQQRLLLETSWEAFERAGIDPSSLRGSRAGVFVGTNGQDYLSLVAR 3385 Query: 1250 AQ----WYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 Q + TG+ SV SGR+SY GL GPA++VDTACSSSLVALH A +LR GEC L Sbjct: 3386 EQDGLEGHVGTGNAGSVMSGRVSYVFGLEGPAVTVDTACSSSLVALHWAIQALRQGECSL 3445 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV++TP FI FSRQRGLA DGR KAFA ADGTG+ EG GML+++RLSDA+R Sbjct: 3446 ALAGGVTVMSTPENFIDFSRQRGLAEDGRIKAFAAGADGTGWGEGVGMLLVERLSDAQRN 3505 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G PVLA++ GSA+NQDGASNGLTAP+GP+QQRVI AL+ AG++ A+VD VEAHGTGTRL Sbjct: 3506 GHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSAAEVDAVEAHGTGTRL 3565 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIEAQALLATYG++ + D PL LGS+KSN+GH+QAAAGVAG+IKMV AM+H +LP TL Sbjct: 3566 GDPIEAQALLATYGQERSADQPLLLGSVKSNIGHTQAAAGVAGIIKMVMAMQHGVLPRTL 3625 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXX 1545 H+D P+ HVDWS G V+LLTE R+WP GRPRRAG+SSFG+SGTNAH Sbjct: 3626 HVDAPTPHVDWSAGEVELLTEQRDWPE-TGRPRRAGISSFGISGTNAHTIIEQAPDTEQS 3684 Query: 1546 XXXXXGPG-----VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG----DVGYSLVTT 1596 P VL +++S +T V AQA L + A D G D+ YSL T+ Sbjct: 3685 APADAQPAVRPARVLPYLLSGKTKEAVRAQAASLTAHLDAAEGADGGVDAEDLAYSLATS 3744 Query: 1597 RSLFEHRAVVVGAGRD--ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLG 1654 R+ + RA +V + D +L LA + G G+ +G A +T F+F GQG+Q LG Sbjct: 3745 RAHLDQRAALVLSVADGQDLRETLARLAAGESVAGITTGTA-GDARTAFLFTGQGSQRLG 3803 Query: 1655 MGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVAL 1714 MGREL +P +LD L RPL++V++G+DA +L+ T + QPALFAVEVAL Sbjct: 3804 MGRELYDAHPVFADALDAVCAQLDAVLDRPLKDVLFGSDASVLDETRYTQPALFAVEVAL 3863 Query: 1715 YRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQ 1774 RL+ESWG+RP + GHS+GE++AAHV+G RGRLMQALP GGVM AVQ Sbjct: 3864 SRLVESWGVRPDFLSGHSIGEIAAAHVAGVFSLEDACALVAARGRLMQALPTGGVMIAVQ 3923 Query: 1775 AGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSV 1834 A E E+ PLL ++VS+AAVNGP SVV++G +A V + A R+ +RL VSHAFHS Sbjct: 3924 ASEDEVLPLLNDRVSIAAVNGPRSVVVAGDEDAALAVAE--AFPDRKSKRLTVSHAFHSP 3981 Query: 1835 LMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCF 1894 M+ MLE FR V + P IPV+SN+TG LV ++ SA++WVRH+REAVRF D V Sbjct: 3982 HMDGMLEDFRQVVAGLSFEAPRIPVVSNLTGALVTDEMASAEFWVRHVREAVRFLDGVRA 4041 Query: 1895 AHSAGATRFVEVGPAGGLTSLIEESLAQVS-VVAVPTLRKDRPEPFXXXXXXXXXXXXXX 1953 +AG T +VE+GP G L++L ++ L + P LR RPE Sbjct: 4042 LEAAGVTAYVELGPDGVLSALAQDCLTDTTHTTFAPALRAGRPEAETLVTALARAHAHGV 4101 Query: 1954 XXDWASVLAGCGGQRVGLPTYAFAHERFW 1982 DW++ AG G +RV LPTYAF +RFW Sbjct: 4102 EVDWSAYFAGSGARRVDLPTYAFQRQRFW 4130 Score = 944 bits (2441), Expect = 0.0 Identities = 522/1011 (51%), Positives = 637/1011 (63%), Gaps = 39/1011 (3%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL++ EQ +L V A L LD ++F D G SL+AV+L RL Sbjct: 74 RLAGLTETEQHTTLLDWVSSLVTASLRDAAPTALDPQRSFLDLGFDSLAAVDLHARLVAG 133 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAA-VRTRVRIDEPIAIVGMGCRYP 1128 TG+ L T AFD+PTP LA + H +APA A V + DEPIAIVG+GCR+P Sbjct: 134 TGLRLPVTLAFDHPTPAHLARRI--HALLLGLTAPAEAPVTAAISSDEPIAIVGIGCRFP 191 Query: 1129 GGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFD 1188 G V SP LW+LVA+G D I EFP RGW+++ L+DPDPD G TY R GGF+ D +FD Sbjct: 192 GDVHSPEALWELVANGTDAISEFPTGRGWNLDSLYDPDPDRAGTTYAREGGFLHDADEFD 251 Query: 1189 PGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTS 1248 FFGISP EALAMDPQQRLLLETSWEA + AGIDP LRG GVFVG YG Sbjct: 252 AAFFGISPREALAMDPQQRLLLETSWEAFDRAGIDPSGLRGGQIGVFVGAETQEYGPRLE 311 Query: 1249 QA----QWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECD 1304 A + Y TG+ SVASGRI+Y G GP ++VDTACSSSL ALHLA +LR+GEC Sbjct: 312 DAADGFEGYLVTGNAASVASGRIAYTFGFEGPTVTVDTACSSSLAALHLAVQALRSGECS 371 Query: 1305 LALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARR 1364 LALAGG ++A+P F+ FSRQRGLA DGRCK FA ADGT + EGAGML+++RLSDAR Sbjct: 372 LALAGGVAIMASPGSFVSFSRQRGLAPDGRCKPFAAGADGTAWGEGAGMLLVERLSDARA 431 Query: 1365 AGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTR 1424 AG +LA++ G+A+NQDGASNGLTAPSGPAQQRVI AL++AG+T ADVD VEAHGTGT Sbjct: 432 AGHHILAVVRGTAINQDGASNGLTAPSGPAQQRVIRQALANAGLTSADVDAVEAHGTGTT 491 Query: 1425 LGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPAT 1484 LGDPIEAQALLATYG+D D PLWLGS+KSN+GH+QAAAGVAGVIKMV AMRH +LP T Sbjct: 492 LGDPIEAQALLATYGQDRPADRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPQT 551 Query: 1485 LHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXX 1544 LH+D P+ HVDW G V LLT+ WP PRRAGVSSFG+SGTNAH Sbjct: 552 LHVDAPTPHVDWEAGAVSLLTQPVAWP-TADAPRRAGVSSFGMSGTNAHAIIEEPPTEDA 610 Query: 1545 XXXXXXGP------------------GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDA 1586 P +L W +SA+T + A A RL +++ + Sbjct: 611 AQHTEDQPPAQEAPATDEPEAAADQLPLLPWALSAKTPEALRATARRLGDWLDTHPDATP 670 Query: 1587 GDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPG-GKTVFVF 1645 D+G+SL TTRS FEHRAVV+G R L GL + E V G PG G+ +F Sbjct: 671 ADIGHSLATTRSRFEHRAVVLGDDRTALQRGLRALAEAADTPAVIHG--EPGAGRPAVLF 728 Query: 1646 PGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG----ADAELLNTTE 1701 GQG+Q L MGREL YP LD L PL +V++ +A LL+ T Sbjct: 729 TGQGSQRLAMGRELYETYPVFADALDDASWYLDEQLEHPLLDVLFADEDTPEAALLHQTA 788 Query: 1702 FAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLM 1761 + QPALFAVEVALYRL+ESWG+RP V GHSVGE++AAHV+G RGRLM Sbjct: 789 YTQPALFAVEVALYRLVESWGLRPAFVAGHSVGEIAAAHVAGVFTLEDACALVAARGRLM 848 Query: 1762 QALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRR 1821 QALP GGVM AVQA E E+ PLL ++VS+AA+NGP SVV++G +A V + AQGR+ Sbjct: 849 QALPTGGVMIAVQASEDEVLPLLTDRVSIAAINGPQSVVVAGDEDAALAVAEAFEAQGRK 908 Query: 1822 VRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTG-QLVAEDYGSADYWVR 1880 +RL VSHAFHS M+ ML+ FR VA + G P +PV+S +TG A + S ++WVR Sbjct: 909 TKRLTVSHAFHSPHMDAMLDAFRRVAQVLDYGTPTLPVVSLLTGTTATAAELASPEHWVR 968 Query: 1881 HIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLA-----QVSVVAVPTLRKDR 1935 H+REAVRF D V + GA F+E+GP LT++ ++ L + V LR R Sbjct: 969 HVREAVRFLDGVRTLRARGADSFLELGPDPVLTAMAQDCLVTDPQDTTNPVFAAALRSGR 1028 Query: 1936 PEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADR 1986 PEP DWA+ AG G + V LPTYAF +R+W+ R Sbjct: 1029 PEPTTLLDAVARMFVRGAETDWAAYFAGTGARSVELPTYAFQRQRYWMNAR 1079 Score = 740 bits (1911), Expect = 0.0 Identities = 429/973 (44%), Positives = 576/973 (59%), Gaps = 33/973 (3%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDV- 75 ++AA G + AE V + ++LG S+ + + L G+ +P ++D P+A + Sbjct: 9757 HVAAVLGHEGAETVGAERAFKELGFDSLTAVELRNRLGAATGVSLPATLIFDYPTASAIT 9816 Query: 76 --IKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEK 133 ++ L G Q +A T A ++PIA++ M+CRF G V LW LA Sbjct: 9817 AFLRDELLGSEVQMTAPVVTAVA-------DDPIAIVAMSCRFPGGVRTPEDLWQLLAAG 9869 Query: 134 KSAITEYPARRLGAAAADWL----GDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALM 186 AI E+P R D L D Q T Y G FL D FD FF I P EA M Sbjct: 9870 GDAIGEFPVDR--GWDLDRLYSPDPDRQGTFYAREGGFLYDAADFDAVFFGISPREALAM 9927 Query: 187 DPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLL--FPGGRKPTIWDNT 244 DPQQRLLLET+W A E AGI P +++ S GVF+G + DY L P G + + T Sbjct: 9928 DPQQRLLLETTWEAFERAGIAPSSVRGSQAGVFIGTNGQDYGATLQALPDGIEGFL--GT 9985 Query: 245 GGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLIS 304 G ++S+++ RLSY + GP++ +DTACS+SLVA H A ++L +GECD+A+ G V+ S Sbjct: 9986 GNAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAIQALRNGECDMALAGGVTVMSS 10045 Query: 305 PEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGS 364 P + F ++ G +AF ADG GEG G++++ERLSDARR G VLAV+ GS Sbjct: 10046 PGAYIDFSRQRGLAADGRIKAFSDDADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGS 10105 Query: 365 AVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQ 424 A+NQDG SNG+ APN +Q V+ +A A + +E+D VEAHGTGT +GD IEA AL Sbjct: 10106 AINQDGASNGLTAPNGPSQQRVIRAALASAGLSSSEVDAVEAHGTGTRLGDPIEAQALLA 10165 Query: 425 VFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPF 484 +G+ R A +PL++GSIK NIGH + AAG+AG++K VL +Q G L + P++ + Sbjct: 10166 TYGQERPADQPLLLGSIKSNIGHTQAAAGVAGVMKMVLAMQHGVLPQTLHVNEATPHVDW 10225 Query: 485 AELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXG----P 540 + +A++ E Q WP GRPRRAG+SSFGF GTNAH P Sbjct: 10226 SAGEVALLTERQAWPE-TGRPRRAGISSFGFSGTNAHTIVEQAPDDIREAASPVAPQQRP 10284 Query: 541 GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRD 600 GV+ WV+S + A + AQA RLL V + L+ DV YSL T+RS E RAVVV RD Sbjct: 10285 GVVPWVLSGKNEAALRAQAERLLAAVTSDELLEPADVAYSLATSRSALERRAVVVAGERD 10344 Query: 601 ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXX 660 E LA L + G GVA G + G + F+F GQG+Q LGMGREL +P Sbjct: 10345 EFLAALRALAAGEQAAGVAHG-TVSAGASAFLFTGQGSQRLGMGRELYDAFPVFADALDA 10403 Query: 661 XXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHS 720 +D HL PL+EV++G+DA LL+ T F QPALFA+EVAL+RLLESWG+RP + GHS Sbjct: 10404 ICARMDGHLELPLKEVLFGSDAALLDETRFTQPALFAIEVALFRLLESWGVRPDFLSGHS 10463 Query: 721 VGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAA 780 +GE++AAHV+G RGRLMQALP GGVM AVQA E+E+ PLL ++VS+AA Sbjct: 10464 IGEIAAAHVAGVFSLDDACALVAARGRLMQALPAGGVMIAVQASEEEVLPLLTDRVSIAA 10523 Query: 781 VNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA 840 VNGP +VV++G +A + V A R+ +RL VSHAFHS M+ ML FR VA+ + Sbjct: 10524 VNGPEAVVVAGDEDAATAVA--AAFPDRKSKRLTVSHAFHSPHMDGMLADFRKVAESLSY 10581 Query: 841 GRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGL 900 P IPV+SN+TG LV ++ SAD+WVRH+REAVRF D + +AG T FVE+GP G L Sbjct: 10582 ESPRIPVVSNLTGALVTDEMASADFWVRHVREAVRFLDGIRVLEAAGVTTFVELGPDGVL 10641 Query: 901 TSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLP 960 ++L ++ Q + VP LRK RPE DW + +G +RV LP Sbjct: 10642 SALAQDCTEQ-DALFVPALRKGRPEAEAVVTALARAHVHGVTVDWTAFYSGTAARRVDLP 10700 Query: 961 TYAFAHERFWLAD 973 TYAF +R+WL + Sbjct: 10701 TYAFQRKRYWLEE 10713 Score = 737 bits (1903), Expect = 0.0 Identities = 430/971 (44%), Positives = 576/971 (59%), Gaps = 29/971 (2%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVI 76 ++AA G + AE V + ++LG S+ + + L G+ +P ++D P+A I Sbjct: 6461 HVAAVLGHEGAETVGAERAFKELGFDSLTAVELRNRLGAATGVSLPATLIFDYPTA-SAI 6519 Query: 77 KSVLGGD--GSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKK 134 + L + G+Q AV ++PIA++ M+CRF G V LW LA Sbjct: 6520 TAFLRDELLGTQARIAGPVSTAV--TPVDDDPIAIVAMSCRFPGGVRTPEDLWQLLAAGG 6577 Query: 135 SAITEYPARRLGAAAADWL----GDEQETIY---GCFLEDVEGFDNKFFDIPPDEAALMD 187 AI E+P R D L D+Q T Y G FL D FD FF I P EA MD Sbjct: 6578 DAIGEFPVDR--GWDLDRLYNPDPDQQGTFYAREGGFLYDAADFDADFFGISPREALAMD 6635 Query: 188 PQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLF--PGGRKPTIWDNTG 245 PQQRLLLET+W E AGI P ++ S GVF+G + DY P G + + TG Sbjct: 6636 PQQRLLLETTWETFERAGIDPAAVRGSQAGVFIGTNGQDYDATFHSVPDGIEGFL--GTG 6693 Query: 246 GSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISP 305 ++S+++ RLSY + GP++ +DTACS+SLVA H A ++L GECD+A+ G V+ SP Sbjct: 6694 NAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAIQALRGGECDMALAGGVTVMSSP 6753 Query: 306 EVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSA 365 + F ++ G +AF A ADG GEG G++++ERLSDA+R G VLAV+ GSA Sbjct: 6754 GAYIDFSRQRGLAEDGRIKAFSADADGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSA 6813 Query: 366 VNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQV 425 +NQDG SNG+ APN +Q V+ +A A + AE+D VEAHGTGT +GD IEA AL Sbjct: 6814 INQDGASNGLTAPNGPSQQRVIRAALASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLAT 6873 Query: 426 FGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFA 485 +G+ R +PL++GSIK NIGH + AAG+AG+IK VL +Q G L + P P++ ++ Sbjct: 6874 YGQERAEEQPLLLGSIKSNIGHTQAAAGVAGVIKMVLAMQHGVLPQTLHVNEPTPHVDWS 6933 Query: 486 ELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP----G 541 +A++ E ++WP GRPRRAG+SSFGF GTNAH G Sbjct: 6934 AGEVALLTEQRDWPE-TGRPRRAGISSFGFSGTNAHTIIEQAPDVLDVEPSVQPQERPGG 6992 Query: 542 VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDE 601 VL WV+SA+ A + QA RLL V + L+ DV YSL T+RS E RAVVV RDE Sbjct: 6993 VLPWVLSAKNEAALRVQAERLLAAVTSDELLEPADVAYSLATSRSALERRAVVVAGERDE 7052 Query: 602 LLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXX 661 LA L + G GVA G A GG T F+F GQG+Q LGMGREL +P Sbjct: 7053 FLAALRALAAGEQTAGVAHGTAAVGG-TAFLFTGQGSQRLGMGRELYDAHPVFADALDAI 7111 Query: 662 XXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSV 721 +D HL PL+EV++G+DA +L+ TE+ QPALFAVEVAL+RL+ESWG+RP + GHS+ Sbjct: 7112 CARMDGHLELPLKEVLFGSDAAVLDRTEYTQPALFAVEVALFRLVESWGIRPDFLSGHSI 7171 Query: 722 GELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAV 781 GE++AAHV+G RGRLMQALP GGVM AV+A E+E+ PLL ++VS+AAV Sbjct: 7172 GEIAAAHVAGVLSLDDACALVAARGRLMQALPSGGVMIAVEASEEEVLPLLTDRVSIAAV 7231 Query: 782 NGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAG 841 NGP SVV++G +A + + A R+ +RL VSHAFHS M+ MLE FR V + Sbjct: 7232 NGPRSVVIAGDEDAAVALAESFA--DRKSKRLTVSHAFHSPHMDGMLEDFRQVVAGLSFE 7289 Query: 842 RPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLT 901 P IPV+SN+TG LV ++ GSA++WVRH+REAVRF D + +AG T +VE+GP G L+ Sbjct: 7290 APRIPVVSNLTGALVTDEMGSAEFWVRHVREAVRFLDGIRVLEAAGVTAYVELGPDGVLS 7349 Query: 902 SLIEESLA--QVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGL 959 +L + LA + + +P LRK RPE DW++ AG G +RV L Sbjct: 7350 ALAQGCLADENSNALFMPALRKGRPEAETLVTTLGQAHAHGVEVDWSAYFAGSGARRVDL 7409 Query: 960 PTYAFAHERFW 970 PTYAF +RFW Sbjct: 7410 PTYAFQRQRFW 7420 Score = 718 bits (1854), Expect = 0.0 Identities = 422/970 (43%), Positives = 567/970 (58%), Gaps = 26/970 (2%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVI 76 ++AA G D A+ V + ++LG S+ + + L + +P V+D P++ + Sbjct: 1640 HVAAVLGHDGADAVGAERAFKELGFDSLTAVDLRNRLGAATALRLPATLVYDYPTS-SAL 1698 Query: 77 KSVLGGD--GSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKK 134 L G+ G+ ADS A + ++PIA++ M+CRF G V LW LA+ Sbjct: 1699 AEYLRGELMGNAPKADSPQHVAAATD---DDPIAIVAMSCRFPGGVRTPEDLWRLLAQGT 1755 Query: 135 SAITEYPARR------LGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDP 188 A+ ++PA R L A + G T G FL D FD FF I P EA MDP Sbjct: 1756 DAVADFPADRGWDLDRLYDANPEQPGTSY-TREGGFLYDAAEFDAGFFGISPREALAMDP 1814 Query: 189 QQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSS 248 QQRLLLETSW A E AGI P LK S GVFVG + DY+ L+ TG ++ Sbjct: 1815 QQRLLLETSWEAFERAGIDPALLKGSQAGVFVGTNGQDYLTLVAGEADGLEGHVGTGNAA 1874 Query: 249 SIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVW 308 S+++ RLSY + GP++ +DTACSSSLVA HLA ++L GEC +A+ G V+ +P+ + Sbjct: 1875 SVVSGRLSYVFGLEGPAITVDTACSSSLVALHLAVQALRQGECSMALAGGVTVMSTPDAF 1934 Query: 309 RGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQ 368 F ++ G +AF A ADG GEG G++++ERLSDA+R G VLAV+ GSA+NQ Sbjct: 1935 IDFSRQRGLAEDGRIKAFAAGADGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSAINQ 1994 Query: 369 DGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGR 428 DG SNG+ APN +Q V+ A A + AE+D VEAHGTGT +GD IEA AL +G+ Sbjct: 1995 DGASNGLTAPNGPSQQRVIRQALASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQ 2054 Query: 429 GRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELG 488 R PL++GS+K NIGH + AAG+AG+IK V+ ++ G L + + P P++ ++ Sbjct: 2055 ERAEGLPLLLGSVKSNIGHTQAAAGVAGIIKMVMAMRHGVLPRTLHVDAPTPHVDWSAGE 2114 Query: 489 LAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH-----XXXXXXXXXXXXXXXXXGPGVL 543 + ++ E ++WP GRPRRAGVSSFG GTNAH L Sbjct: 2115 VELLTEQRDWPE-TGRPRRAGVSSFGLSGTNAHTIIEQAPDADADEAPTAPAEGTATAAL 2173 Query: 544 AWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVV--GAGRDE 601 + V+ + AG+ AQA +L+ ++ + D+ YSL RS FE RAVVV A RD Sbjct: 2174 PFAVTGKNPAGLRAQAQQLVSWLAENPQAAPADIAYSLAAGRSAFETRAVVVPDAADRDA 2233 Query: 602 LLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXX 661 L AGL + G G+ G A GG F+F GQG+Q LGMGREL YP Sbjct: 2234 LTAGLRALAAGEHATGLLRGTA-SGGGLAFLFTGQGSQRLGMGRELYDTYPVFADALDAV 2292 Query: 662 XXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSV 721 +D HL PL +V++G+DA +L+ TE+ QPALFAVEVAL+RL ESWG++P V GHS+ Sbjct: 2293 CARMDAHLELPLTDVLFGSDAAVLDRTEYTQPALFAVEVALFRLAESWGVKPDFVSGHSI 2352 Query: 722 GELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAV 781 GE++AAHV+G RGRLMQALP GGVM AVQA E+E+ PLL E+VS+AAV Sbjct: 2353 GEIAAAHVAGVFSLDDACALVAARGRLMQALPEGGVMIAVQASEEEVLPLLTERVSIAAV 2412 Query: 782 NGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAG 841 NGP SVV++G +A V D A R+ +RL VSHAFHS M+ ML+ FR V + + G Sbjct: 2413 NGPRSVVVAGDEDAALAVAD--AFPDRKSKRLTVSHAFHSPHMDGMLDDFRRVVEGLSFG 2470 Query: 842 RPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLT 901 PAIPV+SN+TG LVA++ GSA++WVRH+REAVRF D V AG T FVE+GP G L+ Sbjct: 2471 APAIPVVSNLTGALVADEMGSAEFWVRHVREAVRFLDGVRVLEGAGVTSFVELGPDGVLS 2530 Query: 902 SLIEESL-AQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLP 960 +L ++ L V VP LR R E DW++ AG G + V LP Sbjct: 2531 ALAQDCLTGDADVAFVPVLRAGRGEAETLVTAVAQAHARGVEVDWSAFFAGTGARSVELP 2590 Query: 961 TYAFAHERFW 970 TYAF +R+W Sbjct: 2591 TYAFQRQRYW 2600 Score = 696 bits (1796), Expect = 0.0 Identities = 415/975 (42%), Positives = 554/975 (56%), Gaps = 33/975 (3%) Query: 19 IAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKS 78 + TG D+ V+ + RDLG S+ + + L G+ +P ++D P+ + + Sbjct: 4948 VLGHTGADA--VDAERAFRDLGFDSLTAVELRNVLKAETGLRLPPTLIFDYPTPVALARH 5005 Query: 79 VLGGDGSQRSADSDTGCAVLGNGP---TNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKS 135 +L + G V T++PI ++GM CR+ G V LW +A Sbjct: 5006 LLAELAVTGDLEVQDGVRVPVRAAVDVTDDPIVIVGMGCRYPGGVRSPEELWQLVATGGD 5065 Query: 136 AITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQ 190 +T +P+ R A + D T G FL DV FD FF I P EA MDPQQ Sbjct: 5066 GVTTFPSDRGWNVEALYHPDPDHAGTSYTREGGFLHDVADFDPAFFGISPREALAMDPQQ 5125 Query: 191 RLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLL-----------FPGGRKPT 239 RLLLETSW A E AGI P TL+ S TGVF GV DYV P G + Sbjct: 5126 RLLLETSWEAFERAGIDPATLRGSRTGVFAGVMYHDYVTGFGLGDGAGSGDALPEGVEGY 5185 Query: 240 IWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGT 299 + TG + SI + R++Y + GP++ +DTACSSSLVA H A ++L GECD+A+ G Sbjct: 5186 L--GTGNAGSIASGRIAYTFGLEGPAVTVDTACSSSLVALHWAIQALRGGECDMALAGGV 5243 Query: 300 NVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLA 359 V+ +PE + F +S G C++F A ADG EG G++++ER SDA R G +LA Sbjct: 5244 AVMATPETFVDFSRQRGLSADGRCKSFAAAADGTGWAEGAGMLLVERQSDALRNGHPILA 5303 Query: 360 VLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEA 419 V+ GSAVNQDG SNG+ APN +Q V+ A A + ++D VEAHGTGT +GD IEA Sbjct: 5304 VVRGSAVNQDGASNGLTAPNGPSQQRVIREALASAGLSAVDVDAVEAHGTGTRLGDPIEA 5363 Query: 420 HALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPN 479 AL +G+ R +PL++GSIK NIGH + AAG+AG+IK V+ ++ G L + + P+ Sbjct: 5364 QALLATYGQDRPEGRPLLLGSIKSNIGHTQAAAGVAGIIKMVMAMRHGVLPQTLHVDAPS 5423 Query: 480 PNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXG 539 + + ++++ + +WP GRPRRAG+SSFG GTNAH Sbjct: 5424 TQVEWEAGDVSLLTQAMDWPQ-TGRPRRAGISSFGISGTNAHTIIEQPPVLERAEPEAAA 5482 Query: 540 --PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGA 597 P V WV+SA+ + AQA +L V + DV +SL R+ FE RA VV A Sbjct: 5483 LLPAV-PWVLSAKGEDALRAQARQLHSHVASTPGARPVDVAWSLAANRASFEDRAAVVAA 5541 Query: 598 GRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXX 657 R+ LLAGLA + EGR + G + GK F+F GQG+Q LGMGREL YP Sbjct: 5542 DREGLLAGLAALAEGRSTATLVEGSPV-AGKLAFLFTGQGSQRLGMGRELYEAYPVFAAA 5600 Query: 658 XXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVM 717 LD L PL+EV++G D E+L+ TEF QPALFAVEVAL+RLLESWG+R + Sbjct: 5601 LDAVCERLDLEL--PLKEVLFGNDREVLDRTEFTQPALFAVEVALFRLLESWGVRADFLS 5658 Query: 718 GHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVS 777 GHSVGE++AAHV+G RGRLMQALP GGVM AVQA E E+ PLL E+VS Sbjct: 5659 GHSVGEIAAAHVAGVFSLDDACALVAARGRLMQALPEGGVMIAVQASEDEVLPLLTERVS 5718 Query: 778 VAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADE 837 +AA+NGP SVV++G +A V A R+ +RL VSHAFHS M+ ML+ FR V + Sbjct: 5719 IAAINGPRSVVVAGDEDAALAVA--AAFPDRKSKRLTVSHAFHSPHMDGMLDDFRRVVEG 5776 Query: 838 VYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPA 897 + P IP++SN+TG L+A++ GSA++WVRH+REAVRF D V AG T FVE+GP Sbjct: 5777 LSFQAPRIPLVSNLTGALIADEMGSAEFWVRHVREAVRFLDGVRALEGAGVTSFVELGPD 5836 Query: 898 GGLTSLIEESLA-QVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQR 956 G L++L ++ LA V VP LR R E DW++ AG G + Sbjct: 5837 GVLSALAQDCLAGDADVAFVPVLRAGRGEAETLVTAVAQAHVRGVEVDWSAFFAGTGARS 5896 Query: 957 VGLPTYAFAHERFWL 971 V LPTYAF +R+WL Sbjct: 5897 VELPTYAFQRQRYWL 5911 Score = 690 bits (1781), Expect = 0.0 Identities = 409/975 (41%), Positives = 563/975 (57%), Gaps = 32/975 (3%) Query: 18 YIAARTGCDSAE-VNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAH--- 73 ++AA G D A+ V + ++LG S+ + + L + +P ++D P++ Sbjct: 3166 HVAAVLGHDGADAVGAERAFKELGFDSLTAVELRNRLGAATELRLPVTLIYDYPTSAALA 3225 Query: 74 DVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEK 133 D ++ L G A AV G +PIA++ M+CRF G + LW LA+ Sbjct: 3226 DHLREELVGSIPVSGALLPVAAAVDG-----DPIAIVAMSCRFPGGIASPEDLWQLLAQG 3280 Query: 134 KSAITEYPARR------LGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMD 187 A+ ++PA R L + D G T +G F+ FD FF I P EA MD Sbjct: 3281 TDAVADFPADRGWNLDRLYSPDPDQPGTSY-TRHGGFVTGAAEFDADFFGISPREALAMD 3339 Query: 188 PQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGS 247 PQQRLLLETSW A E AGI P +L+ S GVFVG + DY+ L+ TG + Sbjct: 3340 PQQRLLLETSWEAFERAGIDPSSLRGSRAGVFVGTNGQDYLSLVAREQDGLEGHVGTGNA 3399 Query: 248 SSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEV 307 S+++ R+SY + GP++ +DTACSSSLVA H A ++L GEC LA+ G V+ +PE Sbjct: 3400 GSVMSGRVSYVFGLEGPAVTVDTACSSSLVALHWAIQALRQGECSLALAGGVTVMSTPEN 3459 Query: 308 WRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVN 367 + F ++ G +AF A ADG GEG G++++ERLSDA+R G VLAV+ GSA+N Sbjct: 3460 FIDFSRQRGLAEDGRIKAFAAGADGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSAIN 3519 Query: 368 QDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFG 427 QDG SNG+ APN +Q V+ A A + AE+D VEAHGTGT +GD IEA AL +G Sbjct: 3520 QDGASNGLTAPNGPSQQRVIRQALASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLATYG 3579 Query: 428 RGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAEL 487 + R A +PL++GS+K NIGH + AAG+AG+IK V+ +Q G L + + P P++ ++ Sbjct: 3580 QERSADQPLLLGSVKSNIGHTQAAAGVAGIIKMVMAMQHGVLPRTLHVDAPTPHVDWSAG 3639 Query: 488 GLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPG-----V 542 + ++ E ++WP GRPRRAG+SSFG GTNAH P V Sbjct: 3640 EVELLTEQRDWPE-TGRPRRAGISSFGISGTNAHTIIEQAPDTEQSAPADAQPAVRPARV 3698 Query: 543 LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAG----DVGYSLVTTRSLFEHRAVVVGAG 598 L +++S +T V AQA L + A D G D+ YSL T+R+ + RA +V + Sbjct: 3699 LPYLLSGKTKEAVRAQAASLTAHLDAAEGADGGVDAEDLAYSLATSRAHLDQRAALVLSV 3758 Query: 599 RD--ELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXX 656 D +L LA + G G+ +G A +T F+F GQG+Q LGMGREL +P Sbjct: 3759 ADGQDLRETLARLAAGESVAGITTGTA-GDARTAFLFTGQGSQRLGMGRELYDAHPVFAD 3817 Query: 657 XXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLV 716 +LD L RPL++V++G+DA +L+ T + QPALFAVEVAL RL+ESWG+RP + Sbjct: 3818 ALDAVCAQLDAVLDRPLKDVLFGSDASVLDETRYTQPALFAVEVALSRLVESWGVRPDFL 3877 Query: 717 MGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQV 776 GHS+GE++AAHV+G RGRLMQALP GGVM AVQA E E+ PLL ++V Sbjct: 3878 SGHSIGEIAAAHVAGVFSLEDACALVAARGRLMQALPTGGVMIAVQASEDEVLPLLNDRV 3937 Query: 777 SVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVAD 836 S+AAVNGP SVV++G +A V + A R+ +RL VSHAFHS M+ MLE FR V Sbjct: 3938 SIAAVNGPRSVVVAGDEDAALAVAE--AFPDRKSKRLTVSHAFHSPHMDGMLEDFRQVVA 3995 Query: 837 EVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGP 896 + P IPV+SN+TG LV ++ SA++WVRH+REAVRF D V +AG T +VE+GP Sbjct: 3996 GLSFEAPRIPVVSNLTGALVTDEMASAEFWVRHVREAVRFLDGVRALEAAGVTAYVELGP 4055 Query: 897 AGGLTSLIEESLAQVS-VVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQ 955 G L++L ++ L + P LR RPE DW++ AG G + Sbjct: 4056 DGVLSALAQDCLTDTTHTTFAPALRAGRPEAETLVTALARAHAHGVEVDWSAYFAGSGAR 4115 Query: 956 RVGLPTYAFAHERFW 970 RV LPTYAF +RFW Sbjct: 4116 RVDLPTYAFQRQRFW 4130 Score = 685 bits (1768), Expect = 0.0 Identities = 399/969 (41%), Positives = 550/969 (56%), Gaps = 24/969 (2%) Query: 19 IAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKS 78 + TG D+ V+ + RDLG S+ + + L G+ +P ++D P+ + + Sbjct: 8239 VLGHTGADA--VDAERAFRDLGFDSLTAVELRNVLKTETGLRLPPTLIFDYPTPAALARH 8296 Query: 79 VLGGDG-SQRSADSDTGCAVLGN-----GPTNEPIAVIGMACRFSGQVHGVGPLWDFLAE 132 +L G + S D D VL T++PI ++GM CR+ G V LW +A Sbjct: 8297 LLSELGVTGASGDQDGSRGVLTPVRAVVDVTDDPIVIVGMGCRYPGGVRTPEELWQLVAS 8356 Query: 133 KKSAITEYPARRLGAAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMD 187 +T +P R A + D T G FL DV FD FF I P EA MD Sbjct: 8357 GGDGVTAFPTDRGWNVEALYHPDPDHVGTSYTREGGFLHDVAEFDAAFFGISPREALAMD 8416 Query: 188 PQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDN---T 244 PQQRLLLETSW A E AGI P TL+ S TGVF GV DY G P + T Sbjct: 8417 PQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGVMYHDYATGYGNGEELPEGVEGYLGT 8476 Query: 245 GGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLIS 304 G S SI + R+SY + GP++ +DTACSSSLVA H A ++L GECD+A+ G V+ + Sbjct: 8477 GNSGSIASGRVSYAFGLEGPAVTVDTACSSSLVALHWAIQALRGGECDMALAGGVAVMAT 8536 Query: 305 PEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGS 364 PE + F +S G C++F A ADG EG G++++ER SDA R G +LAV+ GS Sbjct: 8537 PETFVDFSRQRGLSADGRCKSFAAAADGTGWAEGAGMLLVERQSDALRNGHPILAVVRGS 8596 Query: 365 AVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQ 424 A+NQDG SNG+ APN +Q V+ A A + +++D VEAHGTGT +GD IEA AL Sbjct: 8597 AINQDGASNGLTAPNGPSQQRVIRQALASAGLSTSDVDAVEAHGTGTRLGDPIEAQALLA 8656 Query: 425 VFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPF 484 +G+ R PL++GSIK NIGH + AAG+AG+IK ++ ++ G L + + P+ + + Sbjct: 8657 TYGQDRPEGLPLLLGSIKSNIGHTQAAAGVAGIIKMIMAMRHGVLPQTLHVDTPSTQVEW 8716 Query: 485 AELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP--GV 542 ++++ E +WP GRPRRAGVSSFG GTNAH V Sbjct: 8717 EAGDVSLLTEAMDWPE-TGRPRRAGVSSFGISGTNAHTIIEQPPVLERAEAPAATVPLPV 8775 Query: 543 LAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDEL 602 + WV+SA+ + AQA L + A ++ DV +SL R+ FE RA VV A R+ L Sbjct: 8776 VPWVLSAKGEDALRAQARELQAHLLAAPDVRPVDVAWSLAANRASFEDRAAVVAADREGL 8835 Query: 603 LAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXX 662 LAGLA + EGR + G + GK F+F GQG+Q LGMGREL YP Sbjct: 8836 LAGLAALAEGRSTAALVEGSPV-AGKLAFLFTGQGSQRLGMGRELYEAYPVFAAALDAVC 8894 Query: 663 XELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVG 722 +L+ L PL++V++G +A LL+ T + QPALFAVEVAL+RL+ESWG+RP + GHS+G Sbjct: 8895 EQLNLEL--PLKDVLFGTNAALLDETRYTQPALFAVEVALFRLVESWGIRPDFLSGHSIG 8952 Query: 723 ELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVN 782 E++AAHV+G RGRLMQALP GGVM AV+A E E+ PLL ++VS+AAVN Sbjct: 8953 EIAAAHVAGVFSLEDACTLVAARGRLMQALPSGGVMIAVEASEDEVLPLLTDRVSIAAVN 9012 Query: 783 GPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGR 842 GP SVV++G + + + A R+ +RL VSHAFHS M+ ML++FR V + + Sbjct: 9013 GPRSVVIAGDEDVAVALAESFA--DRKSKRLTVSHAFHSPHMDGMLDEFRQVVEGLSFET 9070 Query: 843 PAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTS 902 P I ++SN+TG V ++ SA++WVRH+R+AVRF D + AG T ++E+GP G L++ Sbjct: 9071 PRIQIVSNLTGAPVTDEMASAEFWVRHVRDAVRFLDGIRALEDAGVTTYLELGPGGVLSA 9130 Query: 903 LIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTY 962 + +E L VP +R RPE +W+ G + V LPTY Sbjct: 9131 MGQECLTGEGAAFVPVMRNGRPETEAMVAAAALAHVRGLKVNWSQFFVGSDARSVELPTY 9190 Query: 963 AFAHERFWL 971 AF +R+WL Sbjct: 9191 AFQRQRYWL 9199 Score = 672 bits (1734), Expect = 0.0 Identities = 409/1002 (40%), Positives = 558/1002 (55%), Gaps = 47/1002 (4%) Query: 11 LQEWFTHYIAARTGCDSAEVNLDLPLR---DLGLGSIDVLAIPGELSDVLGICVPDLAVW 67 L +W + + A D+A LD P R DLG S+ + + L G+ +P + Sbjct: 87 LLDWVSSLVTASLR-DAAPTALD-PQRSFLDLGFDSLAAVDLHARLVAGTGLRLPVTLAF 144 Query: 68 DNPSAHDVIKSVLGGD-GSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPL 126 D+P+ + + + G A++ A+ ++EPIA++G+ CRF G VH L Sbjct: 145 DHPTPAHLARRIHALLLGLTAPAEAPVTAAI----SSDEPIAIVGIGCRFPGDVHSPEAL 200 Query: 127 WDFLAEKKSAITEYPARRLGAAAA--DWLGDEQETIY---GCFLEDVEGFDNKFFDIPPD 181 W+ +A AI+E+P R + D D T Y G FL D + FD FF I P Sbjct: 201 WELVANGTDAISEFPTGRGWNLDSLYDPDPDRAGTTYAREGGFLHDADEFDAAFFGISPR 260 Query: 182 EAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIW 241 EA MDPQQRLLLETSW A + AGI P L+ GVFVG + +Y L + Sbjct: 261 EALAMDPQQRLLLETSWEAFDRAGIDPSGLRGGQIGVFVGAETQEYGPRLEDAADGFEGY 320 Query: 242 DNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNV 301 TG ++S+ + R++Y GP++ +DTACSSSL A HLA ++L SGEC LA+ G + Sbjct: 321 LVTGNAASVASGRIAYTFGFEGPTVTVDTACSSSLAALHLAVQALRSGECSLALAGGVAI 380 Query: 302 LISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVL 361 + SP + F ++P G C+ F A ADG GEG G++++ERLSDAR AG +LAV+ Sbjct: 381 MASPGSFVSFSRQRGLAPDGRCKPFAAGADGTAWGEGAGMLLVERLSDARAAGHHILAVV 440 Query: 362 TGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHA 421 G+A+NQDG SNG+ AP+ AQ V+ A A + A++D VEAHGTGT++GD IEA A Sbjct: 441 RGTAINQDGASNGLTAPSGPAQQRVIRQALANAGLTSADVDAVEAHGTGTTLGDPIEAQA 500 Query: 422 LGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPN 481 L +G+ R A +PL +GS+K NIGH + AAG+AG+IK V+ ++ G L + + P P+ Sbjct: 501 LLATYGQDRPADRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPQTLHVDAPTPH 560 Query: 482 IPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGP- 540 + + ++++ + WP PRRAGVSSFG GTNAH P Sbjct: 561 VDWEAGAVSLLTQPVAWP-TADAPRRAGVSSFGMSGTNAHAIIEEPPTEDAAQHTEDQPP 619 Query: 541 -----------------GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVT 583 +L W +SA+T + A A RL +++ + D+G+SL T Sbjct: 620 AQEAPATDEPEAAADQLPLLPWALSAKTPEALRATARRLGDWLDTHPDATPADIGHSLAT 679 Query: 584 TRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPG-GKTVFVFPGQGAQWLG 642 TRS FEHRAVV+G R L GL + E V G PG G+ +F GQG+Q L Sbjct: 680 TRSRFEHRAVVLGDDRTALQRGLRALAEAADTPAVIHG--EPGAGRPAVLFTGQGSQRLA 737 Query: 643 MGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWG----ADAELLNTTEFAQPALFAV 698 MGREL YP LD L PL +V++ +A LL+ T + QPALFAV Sbjct: 738 MGRELYETYPVFADALDDASWYLDEQLEHPLLDVLFADEDTPEAALLHQTAYTQPALFAV 797 Query: 699 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 758 EVALYRL+ESWG+RP V GHSVGE++AAHV+G RGRLMQALP GGVM Sbjct: 798 EVALYRLVESWGLRPAFVAGHSVGEIAAAHVAGVFTLEDACALVAARGRLMQALPTGGVM 857 Query: 759 YAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHA 818 AVQA E E+ PLL ++VS+AA+NGP SVV++G +A V + AQGR+ +RL VSHA Sbjct: 858 IAVQASEDEVLPLLTDRVSIAAINGPQSVVVAGDEDAALAVAEAFEAQGRKTKRLTVSHA 917 Query: 819 FHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTG-QLVAEDYGSADYWVRHIREAVRFA 877 FHS M+ ML+ FR VA + G P +PV+S +TG A + S ++WVRH+REAVRF Sbjct: 918 FHSPHMDAMLDAFRRVAQVLDYGTPTLPVVSLLTGTTATAAELASPEHWVRHVREAVRFL 977 Query: 878 DSVCFAHSAGATRFVEVGPAGGLTSLIEESLA-----QVSVVAVPTLRKDRPEPFXXXXX 932 D V + GA F+E+GP LT++ ++ L + V LR RPEP Sbjct: 978 DGVRTLRARGADSFLELGPDPVLTAMAQDCLVTDPQDTTNPVFAAALRSGRPEPTTLLDA 1037 Query: 933 XXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLADR 974 DWA+ AG G + V LPTYAF +R+W+ R Sbjct: 1038 VARMFVRGAETDWAAYFAGTGARSVELPTYAFQRQRYWMNAR 1079 Score = 91.3 bits (225), Expect = 2e-15 Identities = 85/271 (31%), Positives = 106/271 (39%), Gaps = 37/271 (13%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L AE + +L +VC AAVLG GA +DA +AF D G SL+AVELRN LKT Sbjct: 8215 RLLALPVAEHEGVLLDLVCGRVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKTE 8274 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTG--------ATPELDRVDALTDLFLQT 2133 TG+ L T FDYPTP LA HLLS L +G TP VD D + Sbjct: 8275 TGLRLPPTLIFDYPTPAALARHLLSELGVTGASGDQDGSRGVLTPVRAVVDVTDDPIVIV 8334 Query: 2134 CDAGRDDDG-------WQIVALAANG-----------RERMTTPVPKREWKEVVLLAGGR 2175 R G WQ+VA +G E + P P G Sbjct: 8335 GMGCRYPGGVRTPEELWQLVASGGDGVTAFPTDRGWNVEALYHPDPDHVGTSYTREGGFL 8394 Query: 2176 SDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGAAQ 2235 DVA + +D + + S A G DP L G+ Sbjct: 8395 HDVAEFDAAFFGISPREALAMDPQQRLLLETSWEAFERAGIDP---------ATLRGSRT 8445 Query: 2236 AILHAVGDHPHLVLAGYSSGGVLAHALGSYL 2266 + V H + GY +G L + YL Sbjct: 8446 GVFAGVMYHDY--ATGYGNGEELPEGVEGYL 8474 Score = 85.9 bits (211), Expect = 7e-14 Identities = 47/87 (54%), Positives = 55/87 (63%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L AE + +L +VC AAVLG GA +DA +AF D G SL+AVELRN LK Sbjct: 4924 RLLALPVAEHEGVLLDLVCGRVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKAE 4983 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L T FDYPTP LA HLL+ L Sbjct: 4984 TGLRLPPTLIFDYPTPVALARHLLAEL 5010 Score = 83.2 bits (204), Expect = 4e-13 Identities = 60/158 (37%), Positives = 79/158 (50%), Gaps = 18/158 (11%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 +L L AEQ +L +V H AAVLG DGA + A +AF + G SL+AV+LRNRL Sbjct: 1620 KLAELPRAEQDRELLGLVRTHVAAVLGHDGADAVGAERAFKELGFDSLTAVDLRNRLGAA 1679 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 T + L AT +DYPT + LA++L L P +P Q A DDD Sbjct: 1680 TALRLPATLVYDYPTSSALAEYLRGELMGNAPKADSP-------------QHVAAATDDD 1726 Query: 2142 GWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDVA 2179 IVA++ + T P+ W+ LLA G VA Sbjct: 1727 PIAIVAMSCRFPGGVRT--PEDLWR---LLAQGTDAVA 1759 Score = 80.9 bits (198), Expect = 2e-12 Identities = 44/87 (50%), Positives = 53/87 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L+ AEQ +L +V H AAVLG DGA + A +AF + G SL+AVELRNRL Sbjct: 3146 RLAALAPAEQTRELLGLVRTHVAAVLGHDGADAVGAERAFKELGFDSLTAVELRNRLGAA 3205 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 T + L T +DYPT LADHL L Sbjct: 3206 TELRLPVTLIYDYPTSAALADHLREEL 3232 Score = 77.8 bits (190), Expect = 2e-11 Identities = 57/153 (37%), Positives = 76/153 (49%), Gaps = 16/153 (10%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 R GL+ E + +L +V H AAVLG +GA + A +AF + G SL+AVELRNRL Sbjct: 6441 RFAGLAAVELERELLGLVRTHVAAVLGHEGAETVGAERAFKELGFDSLTAVELRNRLGAA 6500 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 TGV+L AT FDYPT + + L L A P + T DDD Sbjct: 6501 TGVSLPATLIFDYPTASAITAFLRDELLGTQARIAGP------------VSTAVTPVDDD 6548 Query: 2142 GWQIVALAANGRERMTTPVPKREWKEVVLLAGG 2174 IVA++ + T P+ W+ +L AGG Sbjct: 6549 PIAIVAMSCRFPGGVRT--PEDLWQ--LLAAGG 6577 Score = 76.3 bits (186), Expect = 5e-11 Identities = 53/159 (33%), Positives = 75/159 (47%), Gaps = 16/159 (10%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 R GL E + +L +V H AAVLG +GA + A +AF + G SL+AVELRNRL Sbjct: 9737 RFAGLGAVELERELLGLVRTHVAAVLGHEGAETVGAERAFKELGFDSLTAVELRNRLGAA 9796 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRV-DALTDLFLQTC----DA 2136 TGV+L AT FDYPT + + L L P + V D + +C Sbjct: 9797 TGVSLPATLIFDYPTASAITAFLRDELLGSEVQMTAPVVTAVADDPIAIVAMSCRFPGGV 9856 Query: 2137 GRDDDGWQIVALAANG-----------RERMTTPVPKRE 2164 +D WQ++A + +R+ +P P R+ Sbjct: 9857 RTPEDLWQLLAAGGDAIGEFPVDRGWDLDRLYSPDPDRQ 9895 Score = 58.9 bits (141), Expect = 9e-06 Identities = 34/80 (42%), Positives = 43/80 (53%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL++ EQ +L V A L LD ++F D G SL+AV+L RL Sbjct: 74 RLAGLTETEQHTTLLDWVSSLVTASLRDAAPTALDPQRSFLDLGFDSLAAVDLHARLVAG 133 Query: 2082 TGVTLSATTAFDYPTPTQLA 2101 TG+ L T AFD+PTP LA Sbjct: 134 TGLRLPVTLAFDHPTPAHLA 153 >tr|Q93NW6|Q93NW6_9ACTO Tax_Id=40318 (amphC)SubName: Full=AmphC;[Streptomyces nodosus] Length = 10917 Score = 1010 bits (2612), Expect = 0.0 Identities = 545/986 (55%), Positives = 652/986 (66%), Gaps = 13/986 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 +L GL A ++ A+L +V A VLG A Q++A + F D G SL+AVELRN L + Sbjct: 1654 QLAGLDAAARREALLGLVRTQIAQVLGHADAGQVEAARQFQDLGFDSLTAVELRNGLNSA 1713 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHL--HHQNRSAPAAAVRTRVRIDEPIAIVGMGCRY 1127 TG+ L AT FDYPTP LADHL L N P A D+PI IVGM CRY Sbjct: 1714 TGLRLPATMVFDYPTPNALADHLSDELLGTGDNIPLPTPAGALPATTDDPIVIVGMACRY 1773 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGGV+SP LW+LV+ G D G FP +RGWD++ L+DPDPD G TY R GGF+ D F Sbjct: 1774 PGGVTSPEDLWRLVSEGADATGPFPVNRGWDVDNLYDPDPDRPGHTYVRAGGFLHDAGSF 1833 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--L 1245 D FFG+SP EAL+ D QQRLLLE SWEA+E AGIDP +LRGS TGVF G+ + YG L Sbjct: 1834 DADFFGMSPREALSTDSQQRLLLELSWEAVERAGIDPHSLRGSRTGVFAGVMYNDYGTIL 1893 Query: 1246 GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 + + + G SVASGR+SY LGL GPA++VDTACSSSLV +HLAA +LR GEC L Sbjct: 1894 TGEEYEAFRGNGSAPSVASGRVSYTLGLEGPAVTVDTACSSSLVGMHLAAQALRTGECTL 1953 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV++TPS F+ FSRQRGLA DGR KAFA+AADG +SEG GML+L+R SDA R Sbjct: 1954 ALAGGVTVMSTPSTFVDFSRQRGLAADGRSKAFAEAADGVAWSEGVGMLLLERRSDAIRN 2013 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G +LA+L GSAVNQDGASNGLTAP+GP+QQRVI AL+ G++ DVDVVEAHGTGT L Sbjct: 2014 GHEILAVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALASGGLSPEDVDVVEAHGTGTTL 2073 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIEAQAL+ATYGRD P+ PLWLGS+KSN+GH+QAAAGVAGVIKM+ +MRH LLP TL Sbjct: 2074 GDPIEAQALIATYGRDRDPERPLWLGSVKSNIGHTQAAAGVAGVIKMIMSMRHGLLPQTL 2133 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXX 1545 H+D PS+HVDW G V+LLTE EWP R RRA VSSFG+SGTNAH Sbjct: 2134 HVDAPSSHVDWDAGAVELLTEQTEWPE-NDRVRRAAVSSFGISGTNAH-VIIEQPAAGPA 2191 Query: 1546 XXXXXGPG----VLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFE 1601 GP W +SA+T + QA RLL V A E D+ YSL+T+RS+F+ Sbjct: 2192 PAAPSGPAEELPAAPWPLSAKTPEALRDQAARLLAHVEAHPETRPADIAYSLLTSRSVFD 2251 Query: 1602 HRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCA 1661 HRA V+GA R E L LA + G + +G A GG+T F+F GQG+Q LGMGREL Sbjct: 2252 HRAAVLGADRTEALRALAALAAGTDDSALLTGTAR-GGRTAFLFSGQGSQRLGMGRELYG 2310 Query: 1662 GYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESW 1721 P LD L LREV+WG DA+LLN T + QPALFAVEVALYRL+ESW Sbjct: 2311 RVPVFTEALDAVLAVLDGELEGSLREVMWGEDADLLNETGWTQPALFAVEVALYRLVESW 2370 Query: 1722 GMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELR 1781 G++P V GHS+GE++AAH++G R LMQALP GG M AV+A E E+ Sbjct: 2371 GVKPDFVAGHSIGEIAAAHIAGVLTLADACRLVAARAALMQALPEGGAMIAVEATEDEVL 2430 Query: 1782 PLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLE 1841 PLL VS+AAVNGP SVV+SGA A V QGRR RL VSHAFHS LM+PML+ Sbjct: 2431 PLLTGDVSIAAVNGPSSVVVSGAEAAALAVAGHFTEQGRRTSRLRVSHAFHSPLMDPMLD 2490 Query: 1842 QFRAVADEVYAGRPAIPVISNVTGQLV-AEDYGSADYWVRHIREAVRFADSVCFAHSAGA 1900 +FR+VA+ + PAIPV+SN+TG L D SADYWVRH+R+AVRFAD V G Sbjct: 2491 EFRSVAEGLSYSAPAIPVVSNLTGTLADPADLCSADYWVRHVRDAVRFADCVGTLGEHGV 2550 Query: 1901 TRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASV 1960 T FVE+GP G L+++ ++S+ + V VP LRKDR E DW S Sbjct: 2551 TTFVELGPDGVLSAMAQQSVTE-GAVTVPVLRKDRSEEQALVTALCRLYVLGIDADWTSA 2609 Query: 1961 LAGCGGQRVGLPTYAFAHERFWLADR 1986 L G RV LPTYAF H FW A R Sbjct: 2610 LTVGGAARVDLPTYAFQHRWFWPAAR 2635 Score = 1005 bits (2598), Expect = 0.0 Identities = 540/991 (54%), Positives = 654/991 (65%), Gaps = 16/991 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L+ E++ A+L +V A VLG AA +DA F D G SL+AVELRNRL Sbjct: 8975 RLTALTAEERREALLGLVRTQAALVLGHADAASVDAAAQFRDVGFDSLTAVELRNRLSAA 9034 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHH-QNRSAPAAAVRTR-VRIDEPIAIVGMGCRY 1127 TG+ L+AT FDYP LA HL L + SA A V+ D+PI IVGM CRY Sbjct: 9035 TGLRLTATLVFDYPNAATLASHLHDELFGAETESALALPVKQLPATTDDPIVIVGMACRY 9094 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGGV+SP LW+L+ G D I EFP +RGWDIE ++ PDP+ LG +YTR GGF+ + +F Sbjct: 9095 PGGVASPEDLWRLLLEGTDAITEFPVNRGWDIESVYHPDPEHLGTSYTRSGGFLHEAGEF 9154 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--L 1245 DPGFFG+SP EALA D QQRLLLE+SWEA+E AGIDP LRGS+TGVF G+ YG L Sbjct: 9155 DPGFFGMSPREALATDSQQRLLLESSWEAIERAGIDPVGLRGSATGVFAGVMYSDYGSIL 9214 Query: 1246 GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 G + + G SVASGR+SY G GPA++VDTACSSSLVA+HLAA +LR GEC L Sbjct: 9215 GGKEFEGLQGQGSAGSVASGRVSYTFGFEGPAVTVDTACSSSLVAMHLAAQALRTGECSL 9274 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV++TP F+ FSRQRGL+ DGRCKAF+D+ADG G+SEG GMLVL+R SDA R Sbjct: 9275 ALAGGVTVISTPGTFVEFSRQRGLSPDGRCKAFSDSADGVGWSEGVGMLVLERQSDAIRN 9334 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G +LA+L GSA+NQDGASNGLTAP+GP+QQRVI AL+ G++ DVDVVEAHGTGT L Sbjct: 9335 GHEILAVLRGSAINQDGASNGLTAPNGPSQQRVIRQALASGGLSTGDVDVVEAHGTGTTL 9394 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIEAQALLATYGRD P+ PL LGS+KSN+GH+QAAAGVAGVIKMV +MRH +LP TL Sbjct: 9395 GDPIEAQALLATYGRDRDPEQPLLLGSVKSNIGHTQAAAGVAGVIKMVMSMRHGVLPRTL 9454 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXX 1545 H+D PS+HVDW+ G V+LLTE EWP RRAGVSSFG+SGTNAH Sbjct: 9455 HVDAPSSHVDWTEGAVELLTEQTEWPE-TEHVRRAGVSSFGISGTNAHVILEQPAKVIQG 9513 Query: 1546 XXXXXG---------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTT 1596 P V+ WV+SA+T + QA RLL V DV +SL+ T Sbjct: 9514 TVVAASAAPESDVVEPSVVPWVLSAKTPEALRDQAARLLAAVTEEPAPRPADVAHSLLVT 9573 Query: 1597 RSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMG 1656 RSLF HRAVV+ E + L + G SG + G++ +F GQG+Q LGMG Sbjct: 9574 RSLFAHRAVVLAGEHQETVRALTVLAAGATDPTAVSG-TVASGRSAALFSGQGSQRLGMG 9632 Query: 1657 RELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYR 1716 REL +P LD L LREV+WG DA LLN T + QPALFAVEVALYR Sbjct: 9633 RELYGRFPVFAEVLDAVLAVLDGELGGSLREVMWGEDAGLLNETGWTQPALFAVEVALYR 9692 Query: 1717 LLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAG 1776 L+ESWG+RP V GHS+GE++AAH++G RGRLMQALP GG M AVQA Sbjct: 9693 LVESWGVRPDFVAGHSIGEIAAAHIAGVFSLEDAARLVAARGRLMQALPAGGAMVAVQAT 9752 Query: 1777 EQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLM 1836 E E+ P L + VS+AA+NGP SVVLSG AV + R A+GR+ RL VSHAFHS LM Sbjct: 9753 EDEVVPHLSDGVSIAALNGPTSVVLSGVESAVLELAARFEAEGRKTTRLRVSHAFHSPLM 9812 Query: 1837 EPMLEQFRAVADEVYAGRPAIPVISNVTGQL-VAEDYGSADYWVRHIREAVRFADSVCFA 1895 +PML++FRAVA+ + P IPV+SN+TG L AE+ S +YWVRH+REAVRFAD V Sbjct: 9813 DPMLDEFRAVAEGLSYAAPVIPVVSNLTGSLATAEELCSPEYWVRHVREAVRFADGVAVL 9872 Query: 1896 HSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXX 1955 + G T F+E+GP G L+++ +ESL V +P LRKDR E Sbjct: 9873 EAQGVTTFLELGPDGVLSAMAQESLTGDETVTIPLLRKDRDEETTALLARAGLYTRGIGG 9932 Query: 1956 DWASVLAGCGGQRVGLPTYAFAHERFWLADR 1986 W +LAG G +RV LPTYAF H+ FW R Sbjct: 9933 GWQDLLAGTGARRVNLPTYAFQHQWFWPTGR 9963 Score = 990 bits (2560), Expect = 0.0 Identities = 525/979 (53%), Positives = 651/979 (66%), Gaps = 8/979 (0%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL GL ++ +L +V A VLG + +DA +AF D G SL+AVELRNRL+T Sbjct: 3395 RLAGLDREQRHEVLLDLVRTSAALVLGHAAGSDIDADRAFRDLGFDSLTAVELRNRLRTA 3454 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TG+ LSAT FD+PT + LADHLL+ L D+PI IVGM CR+PG Sbjct: 3455 TGLRLSATMVFDHPTLSALADHLLTELFGAEAETLTPVTLLPPTDDDPIVIVGMACRFPG 3514 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 V+SP LW+LV+ G D I +FP +RGWD++ L+ PDP+ G +YTR GGF+ D DFDP Sbjct: 3515 DVTSPEDLWRLVSEGTDAISDFPANRGWDVDSLYHPDPEHSGTSYTRSGGFLHDAGDFDP 3574 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--LGT 1247 FFG+SP EALA D QQRLLLETSWEA+E AGIDP +LR S TGVF G+ YG LG Sbjct: 3575 DFFGMSPREALATDSQQRLLLETSWEAIERAGIDPLSLRDSRTGVFAGVMYHDYGSLLGG 3634 Query: 1248 SQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLAL 1307 + + + G SVASGR+SY G GPA++VDTACSSSLVALH AA +LR+GEC LAL Sbjct: 3635 KEFEGFQGQGSAGSVASGRVSYTFGFEGPAVTVDTACSSSLVALHWAAQALRSGECSLAL 3694 Query: 1308 AGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQ 1367 AGG TV++TPS FI FSRQ+GL+ DGR KAFA++ADG G+SEG GML+L+R SDA R G Sbjct: 3695 AGGVTVMSTPSTFIEFSRQQGLSADGRSKAFAESADGVGWSEGVGMLLLERQSDAIRNGH 3754 Query: 1368 PVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGD 1427 +LA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+ G++ DVD VEAHGTGT LGD Sbjct: 3755 EILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASGGLSTGDVDAVEAHGTGTTLGD 3814 Query: 1428 PIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHI 1487 PIEAQAL+ATYG++ T + PLWLGS+KSN+GH+QAAAGVAGVIKMV +MRH +LP TLH+ Sbjct: 3815 PIEAQALIATYGQNRTDEQPLWLGSLKSNIGHTQAAAGVAGVIKMVMSMRHGVLPCTLHV 3874 Query: 1488 DQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXX 1547 D PS+HVDW+ G V+LLTE EWP R RRA VSSFG+SGTNAH Sbjct: 3875 DAPSSHVDWTEGAVELLTEQTEWPE-TDRVRRAAVSSFGISGTNAHVILEQPVVAPAPAT 3933 Query: 1548 XXXG---PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRA 1604 P V+ ++S ++ + QA RLL+ VR L D+G+SL T+RS F+HRA Sbjct: 3934 ADVDGAEPAVVPLILSGKSPEALRDQAARLLDTVREHTALRPLDLGHSLATSRSAFDHRA 3993 Query: 1605 VVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYP 1664 VV+ GR++ L L + + +G G+ +F GQG+Q LGMGREL +P Sbjct: 3994 VVLATGREDALRALTALADDEANSAAVTG-RTRSGRRAALFSGQGSQRLGMGRELYGRFP 4052 Query: 1665 XXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMR 1724 LD L LREV+WG DA LLN T + QPALFAVEVALYRL+ESWG+R Sbjct: 4053 VFAEALDAVLAVLDGELEGSLREVMWGEDAGLLNETGWTQPALFAVEVALYRLVESWGVR 4112 Query: 1725 PGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLL 1784 P V GHS+GE++AAH++G RGRLMQALP GG M AVQA E E+ P L Sbjct: 4113 PDFVAGHSIGEIAAAHIAGVFSLEDAARLVAARGRLMQALPAGGAMVAVQATEDEVIPYL 4172 Query: 1785 GEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFR 1844 ++VS+AA+NGP SVV+SGA AV V R A+GR+ L VSHAFHS LM+ ML++FR Sbjct: 4173 SDEVSIAALNGPASVVVSGAEGAVLEVAARFEAEGRKATMLRVSHAFHSPLMDLMLDEFR 4232 Query: 1845 AVADEVYAGRPAIPVISNVTGQL-VAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRF 1903 AVA+ + P IPV+SN+TG L AE+ S +YWVRH+REAVRFAD V + G T F Sbjct: 4233 AVAETLSFAAPVIPVVSNLTGSLATAEELCSPEYWVRHVREAVRFADGVSALEAQGVTTF 4292 Query: 1904 VEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAG 1963 +E+GP G L+++ +ESL V V LRKDR E DW + AG Sbjct: 4293 LELGPDGVLSAMAQESLTGDEAVTVALLRKDRDEETAALTALAALHTAGVRLDWNAFFAG 4352 Query: 1964 CGGQRVGLPTYAFAHERFW 1982 G RV LPTYAF H +W Sbjct: 4353 TGATRVDLPTYAFQHTTYW 4371 Score = 990 bits (2560), Expect = 0.0 Identities = 525/986 (53%), Positives = 651/986 (66%), Gaps = 13/986 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L E++ ++ +V A VLG A + +AF D G SL++VELRNRL + Sbjct: 7211 RLAVLDAVERREVLVDLVRGQVALVLGHADATAVHPTRAFRDLGFDSLTSVELRNRLNAV 7270 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPG 1129 TG+ L AT FDYPT L D +L L A T D+PI IVGM CRYPG Sbjct: 7271 TGLRLPATMVFDYPTVEVLVDFILDELLGTEVEAEVVQRGTAAVADDPIVIVGMACRYPG 7330 Query: 1130 GVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDP 1189 GV+SP LW+LV G D + FP +RGWD+E L+ PDPD +G +YTR GGF+ + +FDP Sbjct: 7331 GVASPEDLWRLVTEGTDAVSAFPVNRGWDVENLYHPDPDNIGTSYTRSGGFLHEAGEFDP 7390 Query: 1190 GFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--LGT 1247 GFFG+SP EAL+ D QQRLLLETSWEA+E AGIDP LRGS+TGVF G+ Y L + Sbjct: 7391 GFFGMSPREALSTDSQQRLLLETSWEAIERAGIDPVGLRGSATGVFAGVMYSDYSAMLAS 7450 Query: 1248 SQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLAL 1307 + + + +G SVASGR+SY G GPA++VDTACSSSLVA+H A +LR+GE LAL Sbjct: 7451 PEFEGFQGSGSSPSVASGRVSYTFGFEGPAVTVDTACSSSLVAMHWAMQALRSGEISLAL 7510 Query: 1308 AGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQ 1367 AGG TV++TP +F+ F+RQRGL+ DGRCKAF+D+ADG G+SEG GMLVL+R SDA R G Sbjct: 7511 AGGVTVMSTPGVFVDFARQRGLSPDGRCKAFSDSADGVGWSEGVGMLVLERQSDAIRNGH 7570 Query: 1368 PVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGD 1427 +LA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+ G++ ++DVVEAHGTGT LGD Sbjct: 7571 EILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASGGLSAQEIDVVEAHGTGTTLGD 7630 Query: 1428 PIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHI 1487 PIEAQALLATYGRD P+ PLWLGS+KSN+GH+QAAAGVAGVIKMV +MRH +LP TLH+ Sbjct: 7631 PIEAQALLATYGRDRDPEQPLWLGSVKSNIGHTQAAAGVAGVIKMVMSMRHGVLPRTLHV 7690 Query: 1488 DQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXX 1547 D PS+HVDW+ G V+LLTE EWP RRAGVSSFG+SGTNAH Sbjct: 7691 DAPSSHVDWTEGAVELLTEQTEWPE-TEHVRRAGVSSFGISGTNAHVILEQPAKVIQGTV 7749 Query: 1548 XXXG--------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSL 1599 P V+ WV+S +T + +QA +LL V A + DVG SLV RSL Sbjct: 7750 IGGSTPESGVVEPSVVPWVLSGKTPEALRSQAAKLLASVEAELDRPLVDVGSSLVAARSL 7809 Query: 1600 FEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGREL 1659 FEHRAVV+ D LA + G P SG A G++ +F GQG+Q LGMGREL Sbjct: 7810 FEHRAVVLATDADTAARALAALAVGEPDPAAVSGPART-GRSAALFSGQGSQRLGMGREL 7868 Query: 1660 CAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLE 1719 +P LD L LREV+WG DA LLN T + QPALFAVEVAL+RL+E Sbjct: 7869 YGRFPVFAEALDAVLAVLDGELDGSLREVMWGEDAGLLNETGWTQPALFAVEVALHRLVE 7928 Query: 1720 SWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQE 1779 S+G+ P V GHS+GE++AAH++G RGRLMQALP GG M AVQA E E Sbjct: 7929 SFGVTPDFVAGHSIGEIAAAHIAGVFSLEDAARLVAARGRLMQALPAGGAMVAVQATEDE 7988 Query: 1780 LRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPM 1839 + P L ++VS+AA+NGP SVV+SGA AV V R A+GR+ L VSHAFHS LM+PM Sbjct: 7989 VIPYLSDEVSIAALNGPASVVVSGAEGAVLEVAARFEAEGRKATMLRVSHAFHSPLMDPM 8048 Query: 1840 LEQFRAVADEVYAGRPAIPVISNVTGQL-VAEDYGSADYWVRHIREAVRFADSVCFAHSA 1898 L++FRAVA+ + P IPV+SN+TG L AE+ S +YWVRH+REAVRFAD V Sbjct: 8049 LDEFRAVAEGLSFAAPVIPVVSNLTGSLATAEELCSPEYWVRHVREAVRFADGVTTLEEQ 8108 Query: 1899 GATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWA 1958 G T F+E+GP G L+++ +ESL V VP LRK+ E DW+ Sbjct: 8109 GVTTFLELGPDGVLSAMAQESLTGDEAVTVPLLRKNTAEEAATVAALARLHIGGLRIDWS 8168 Query: 1959 SVLAGCGGQRVGLPTYAFAHERFWLA 1984 ++ AG G +RV LPTYAF H+ FW A Sbjct: 8169 ALFAGTGARRVELPTYAFQHQWFWPA 8194 Score = 987 bits (2551), Expect = 0.0 Identities = 527/987 (53%), Positives = 650/987 (65%), Gaps = 16/987 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 1069 RL L E++ A+L +V E A VLG G +D +AF D G SL+AVELRNRL Sbjct: 5467 RLTRLQRTERRDALLTLVREQAALVLGHSGGGGIDPSRAFRDLGFDSLTAVELRNRLGAA 5526 Query: 1070 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPA--AAVRTRVRIDEPIAIVGMGCRY 1127 TGV LSAT FDYPT L DHLL+ L + + A AA + D+PI IVGM CR+ Sbjct: 5527 TGVRLSATAVFDYPTVVALVDHLLTELLGPDAESDAEEAAPAEALLDDDPIVIVGMACRF 5586 Query: 1128 PGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADF 1187 PGG++SP LW+L+ G DVI +FP +RGWD++ L+DPDP G +YTR GGF+ + ADF Sbjct: 5587 PGGITSPEDLWRLLGEGSDVISDFPVNRGWDVDSLYDPDPAHTGTSYTRSGGFLHNAADF 5646 Query: 1188 DPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYG--L 1245 D FFG+SP EA+A D QQRLLLE++WEA+E AGIDP LRGS TGVF G+ GYG L Sbjct: 5647 DADFFGMSPREAMATDSQQRLLLESTWEAIERAGIDPVTLRGSRTGVFAGVMYSGYGTAL 5706 Query: 1246 GTSQAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDL 1305 + + + G SVASGR+SY G GPA+++DTACSS+LVA+HLAA +LR+GEC L Sbjct: 5707 DGDEFEGFQGQGSALSVASGRVSYTFGFEGPAMTIDTACSSALVAMHLAAQALRSGECSL 5766 Query: 1306 ALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA 1365 ALAGG TV++ P F+ FSRQRGL+ DGRCK F+++ADG G+SEG GML+L+R SDA R Sbjct: 5767 ALAGGVTVMSIPDTFVEFSRQRGLSPDGRCKPFSESADGVGWSEGVGMLLLERQSDAIRN 5826 Query: 1366 GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRL 1425 G VLA++ GSAVNQDGASNGLTAP+GP+QQRVI AL+ G++ DVD VEAHGTGT L Sbjct: 5827 GHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASGGLSTGDVDAVEAHGTGTTL 5886 Query: 1426 GDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATL 1485 GDPIEAQALLATYG++ D PL LGS+KSN+GH+QAAAG AGVIKMV AM+H +LP +L Sbjct: 5887 GDPIEAQALLATYGQNRPEDRPLLLGSVKSNIGHTQAAAGAAGVIKMVMAMQHGVLPRSL 5946 Query: 1486 HIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXX 1545 +I +PS+HVDWS G V+LLTE EWP R RRAGVSSFG+SGTNAH Sbjct: 5947 NISEPSSHVDWSAGAVELLTEQTEWPE-TDRVRRAGVSSFGISGTNAHVILEQPAKVIQG 6005 Query: 1546 XXXXXG---------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTT 1596 P V+ WV+S +T + QA RLL V DV SL T Sbjct: 6006 TVVAASAAPGPDVVEPAVVPWVLSGKTPEALRDQAARLLATVTEEPAPRPVDVALSLATQ 6065 Query: 1597 RSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMG 1656 RS F HR VV+ +E + LA + +G P V +G + G+ +F GQG+Q LGMG Sbjct: 6066 RSQFAHRGVVLAGEHEETVRALAALADGEPHSSVTTG-TVSSGRRAALFSGQGSQRLGMG 6124 Query: 1657 RELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYR 1716 REL +P LD L LREV+WG DA LLN T + QPALFAVEVALYR Sbjct: 6125 RELYGRFPVFAEALDAVLAVLDGELGGSLREVMWGEDAGLLNETGWTQPALFAVEVALYR 6184 Query: 1717 LLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAG 1776 L+ESWG+RP V GHS+GE++AAH++G RGRLMQALP GG M AVQA Sbjct: 6185 LVESWGVRPDFVAGHSIGEIAAAHIAGVFSLEDAARLVAARGRLMQALPAGGAMVAVQAT 6244 Query: 1777 EQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLM 1836 E E+ P L + VS+AA+NGP SVV+SG +AV V R A+GR+ RL VSHAFHS LM Sbjct: 6245 EDEVVPHLSDGVSIAALNGPTSVVVSGVEDAVLEVAARFEAEGRKTTRLRVSHAFHSPLM 6304 Query: 1837 EPMLEQFRAVADEVYAGRPAIPVISNVTGQL-VAEDYGSADYWVRHIREAVRFADSVCFA 1895 +PML++FRAVA+ + P IPV+SN+TG L AE+ S +YWVRH+REAVRFAD V Sbjct: 6305 DPMLDEFRAVAEGLSFAAPVIPVVSNLTGSLATAEELCSPEYWVRHVREAVRFADGVAAL 6364 Query: 1896 HSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXX 1955 + G T F+E+GP G L+++ +ESL V +P LRKDR E Sbjct: 6365 EAQGVTTFLELGPDGVLSAMAQESLTGDETVTIPLLRKDRDEETAALTALGRLHATGTRV 6424 Query: 1956 DWASVLAGCGGQRVGLPTYAFAHERFW 1982 DWA LA G + V LPTYAF H FW Sbjct: 6425 DWAGFLAPAGARTVDLPTYAFQHRPFW 6451 Score = 881 bits (2276), Expect = 0.0 Identities = 477/899 (53%), Positives = 594/899 (66%), Gaps = 33/899 (3%) Query: 1093 LSHLHHQNRSAPAAAVRTRVRIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFP 1152 + L QN A+A EPIA+VG+GCR+PGGV SP LW+LVA G DVIG FP Sbjct: 19 IERLRKQNEQLVASAA-------EPIAVVGIGCRFPGGVVSPEDLWELVAEGRDVIGPFP 71 Query: 1153 PDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLET 1212 DRGWD++RL G + + GGF+ D A FDPGFFGISP EA+AMDPQQR+LLE Sbjct: 72 TDRGWDLDRLAGGGE---GSSLAQVGGFLDDAAGFDPGFFGISPREAVAMDPQQRILLEI 128 Query: 1213 SWEALEDAGIDPQALRGSSTGVFVGIYGDGYG----LGTSQAQWYADTGHITSVASGRIS 1268 +WEALE AGIDP ALRGS TGVF+G G YG A+ Y+ TGH SV SGR+S Sbjct: 129 AWEALERAGIDPSALRGSRTGVFMGTTGQDYGEVIKASDEDAEVYSTTGHAASVISGRLS 188 Query: 1269 YCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRG 1328 Y LG GPA++VDT CSSSLV+LHLAA +LR GEC LALAGG++V+ATP FI F+ Q G Sbjct: 189 YFLGAEGPAVTVDTGCSSSLVSLHLAAQALRGGECSLALAGGASVMATPHPFIAFTSQSG 248 Query: 1329 LATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLT 1388 LA DGRCK F+D ADGTG++EGAG+ +L RLSDA+R G+ VLA+L GSA+NQDGASNGLT Sbjct: 249 LAADGRCKPFSDDADGTGWAEGAGLFILMRLSDAQREGRKVLAVLRGSALNQDGASNGLT 308 Query: 1389 APSGPAQQRVISAALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPL 1448 AP+GP+QQRVI AL+ AG+ +DVD VEAHGTGT LGDPIEAQALLATYG++ + PL Sbjct: 309 APNGPSQQRVIRQALAHAGLQASDVDAVEAHGTGTPLGDPIEAQALLATYGQNR--ERPL 366 Query: 1449 WLGSIKSNMGHSQAAAGVAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAR 1508 LGS+KSN+GH+QAA+G AGVIKM+ A++H +LP +LH ++P+++VDW+ G V+LL A Sbjct: 367 LLGSVKSNIGHAQAASGAAGVIKMIMAIQHGVLPRSLHAERPTSNVDWTAGAVELLDRAV 426 Query: 1509 EWPAVVGRPRRAGVSSFGVSGTNAHXXXXXXXXXXXXXXXXXG--PGVLAWVVSARTAAG 1566 +WP GR RRAGVSSFG+SGTNAH P ++ W +S RTAA Sbjct: 427 DWPE-TGRARRAGVSSFGISGTNAHLILEQAPTAPERPAPDPAARPALVPWTLSGRTAAA 485 Query: 1567 VGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRP 1626 + AQ RL + + D D+G++L R+ FEHRAV++ AG D A E+ G Sbjct: 486 LDAQRERLAAHLESHPGADPLDIGFALADGRATFEHRAVLLCAGTDASAA--TEIAHG-- 541 Query: 1627 GVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLR 1686 ++ G + +F GQG+Q LGMGREL A +P LDRH RPLR Sbjct: 542 --------SVDDGASAVLFSGQGSQRLGMGRELHARFPVFAEAFDEIAALLDRHTDRPLR 593 Query: 1687 EVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXX 1746 EVVWG+DAELLN T + QPALFAVEVALYRL+ S G+ P V GHS+GE++AAHV+G Sbjct: 594 EVVWGSDAELLNETGWTQPALFAVEVALYRLVSSLGVTPDYVGGHSIGEIAAAHVAGVLS 653 Query: 1747 XXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGARE 1806 R RLMQ LP GG M AV+A E+E+ P L E+VS+A+VNGP SVV++G + Sbjct: 654 LEDACALVAARARLMQELPRGGAMLAVRATEEEVAPHLTERVSIASVNGPSSVVVAGDED 713 Query: 1807 AVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQ 1866 V+ + AQ R+ RL VSHAFHS LM+PMLE+FR VA + P IPV+SN+TG Sbjct: 714 EVAAIAAHFEAQDRKTTRLRVSHAFHSPLMDPMLEEFRRVARGLTYHEPRIPVVSNLTGA 773 Query: 1867 LV-AEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSV 1925 + D +ADYWVRH+REAVRFAD V G T +EVGP G L+++ +ESL + Sbjct: 774 IADPADLCTADYWVRHVREAVRFADGVTTLAGRGVTTLLEVGPDGVLSAMAQESLPE-GT 832 Query: 1926 VAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 1984 VP LRKDRPE WA + G R LPTY F ++R W A Sbjct: 833 TGVPLLRKDRPEEESALTGLARVHVRGLTVRWARLFDSAGAGRADLPTYPFQNQRVWPA 891 Score = 717 bits (1850), Expect = 0.0 Identities = 417/967 (43%), Positives = 553/967 (57%), Gaps = 25/967 (2%) Query: 26 DSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGGDGS 85 D+A V+ RD+G S+ + + LS G+ + V+D P+A + + Sbjct: 9004 DAASVDAAAQFRDVGFDSLTAVELRNRLSAATGLRLTATLVFDYPNAATLASHL---HDE 9060 Query: 86 QRSADSDTGCAVLGN---GPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPA 142 A++++ A+ T++PI ++GMACR+ G V LW L E AITE+P Sbjct: 9061 LFGAETESALALPVKQLPATTDDPIVIVGMACRYPGGVASPEDLWRLLLEGTDAITEFPV 9120 Query: 143 RRLGAAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETS 197 R + + D + T G FL + FD FF + P EA D QQRLLLE+S Sbjct: 9121 NRGWDIESVYHPDPEHLGTSYTRSGGFLHEAGEFDPGFFGMSPREALATDSQQRLLLESS 9180 Query: 198 WAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSY 257 W A+E AGI P L+ S TGVF GV +DY +L GG++ G + S+ + R+SY Sbjct: 9181 WEAIERAGIDPVGLRGSATGVFAGVMYSDYGSIL--GGKEFEGLQGQGSAGSVASGRVSY 9238 Query: 258 FLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVV 317 GP++ +DTACSSSLVA HLA ++L +GEC LA+ G V+ +P + F + Sbjct: 9239 TFGFEGPAVTVDTACSSSLVAMHLAAQALRTGECSLALAGGVTVISTPGTFVEFSRQRGL 9298 Query: 318 SPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMA 377 SP G C+AF ADG+ EG G++VLER SDA R G +LAVL GSA+NQDG SNG+ A Sbjct: 9299 SPDGRCKAFSDSADGVGWSEGVGMLVLERQSDAIRNGHEILAVLRGSAINQDGASNGLTA 9358 Query: 378 PNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLM 437 PN +Q V+ A + ++D VEAHGTGT++GD IEA AL +GR R +PL+ Sbjct: 9359 PNGPSQQRVIRQALASGGLSTGDVDVVEAHGTGTTLGDPIEAQALLATYGRDRDPEQPLL 9418 Query: 438 IGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQE 497 +GS+K NIGH + AAG+AG+IK V+ ++ G L + + P+ ++ + E + ++ E E Sbjct: 9419 LGSVKSNIGHTQAAAGVAGVIKMVMSMRHGVLPRTLHVDAPSSHVDWTEGAVELLTEQTE 9478 Query: 498 WPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXG---------PGVLAWVVS 548 WP RRAGVSSFG GTNAH P V+ WV+S Sbjct: 9479 WPETE-HVRRAGVSSFGISGTNAHVILEQPAKVIQGTVVAASAAPESDVVEPSVVPWVLS 9537 Query: 549 ARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAE 608 A+T + QA RLL V DV +SL+ TRSLF HRAVV+ E + L Sbjct: 9538 AKTPEALRDQAARLLAAVTEEPAPRPADVAHSLLVTRSLFAHRAVVLAGEHQETVRALTV 9597 Query: 609 VVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRH 668 + G SG + G++ +F GQG+Q LGMGREL +P LD Sbjct: 9598 LAAGATDPTAVSGT-VASGRSAALFSGQGSQRLGMGRELYGRFPVFAEVLDAVLAVLDGE 9656 Query: 669 LARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAH 728 L LREV+WG DA LLN T + QPALFAVEVALYRL+ESWG+RP V GHS+GE++AAH Sbjct: 9657 LGGSLREVMWGEDAGLLNETGWTQPALFAVEVALYRLVESWGVRPDFVAGHSIGEIAAAH 9716 Query: 729 VSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVV 788 ++G RGRLMQALP GG M AVQA E E+ P L + VS+AA+NGP SVV Sbjct: 9717 IAGVFSLEDAARLVAARGRLMQALPAGGAMVAVQATEDEVVPHLSDGVSIAALNGPTSVV 9776 Query: 789 LSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVI 848 LSG AV + R A+GR+ RL VSHAFHS LM+PML++FRAVA+ + P IPV+ Sbjct: 9777 LSGVESAVLELAARFEAEGRKTTRLRVSHAFHSPLMDPMLDEFRAVAEGLSYAAPVIPVV 9836 Query: 849 SNVTGQL-VAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEES 907 SN+TG L AE+ S +YWVRH+REAVRFAD V + G T F+E+GP G L+++ +ES Sbjct: 9837 SNLTGSLATAEELCSPEYWVRHVREAVRFADGVAVLEAQGVTTFLELGPDGVLSAMAQES 9896 Query: 908 LAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHE 967 L V +P LRKDR E W +LAG G +RV LPTYAF H+ Sbjct: 9897 LTGDETVTIPLLRKDRDEETTALLARAGLYTRGIGGGWQDLLAGTGARRVNLPTYAFQHQ 9956 Query: 968 RFWLADR 974 FW R Sbjct: 9957 WFWPTGR 9963 Score = 707 bits (1824), Expect = 0.0 Identities = 424/995 (42%), Positives = 561/995 (56%), Gaps = 37/995 (3%) Query: 1 VTDGLHSADALQEWFTHYIAARTG-CDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGI 59 V D + + L + +A G D+ V+ RDLG S+ + + L+ V G+ Sbjct: 7214 VLDAVERREVLVDLVRGQVALVLGHADATAVHPTRAFRDLGFDSLTSVELRNRLNAVTGL 7273 Query: 60 CVPDLAVWDNPSAHDVIKSVLGGDGSQRSADSDTGCAVLGNGPT---NEPIAVIGMACRF 116 +P V+D P+ ++ +L ++ V+ G ++PI ++GMACR+ Sbjct: 7274 RLPATMVFDYPTVEVLVDFIL-----DELLGTEVEAEVVQRGTAAVADDPIVIVGMACRY 7328 Query: 117 SGQVHGVGPLWDFLAEKKSAITEYPARR------LGAAAADWLGDEQETIYGCFLEDVEG 170 G V LW + E A++ +P R L D +G T G FL + Sbjct: 7329 PGGVASPEDLWRLVTEGTDAVSAFPVNRGWDVENLYHPDPDNIGTSY-TRSGGFLHEAGE 7387 Query: 171 FDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRL 230 FD FF + P EA D QQRLLLETSW A+E AGI P L+ S TGVF GV +DY + Sbjct: 7388 FDPGFFGMSPREALSTDSQQRLLLETSWEAIERAGIDPVGLRGSATGVFAGVMYSDYSAM 7447 Query: 231 L----FPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSL 286 L F G + +G S S+ + R+SY GP++ +DTACSSSLVA H A ++L Sbjct: 7448 LASPEFEG------FQGSGSSPSVASGRVSYTFGFEGPAVTVDTACSSSLVAMHWAMQAL 7501 Query: 287 ASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLER 346 SGE LA+ G V+ +P V+ F +SP G C+AF ADG+ EG G++VLER Sbjct: 7502 RSGEISLALAGGVTVMSTPGVFVDFARQRGLSPDGRCKAFSDSADGVGWSEGVGMLVLER 7561 Query: 347 LSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEA 406 SDA R G +LAV+ GSAVNQDG SNG+ APN +Q V+ A + EID VEA Sbjct: 7562 QSDAIRNGHEILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASGGLSAQEIDVVEA 7621 Query: 407 HGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQR 466 HGTGT++GD IEA AL +GR R +PL +GS+K NIGH + AAG+AG+IK V+ ++ Sbjct: 7622 HGTGTTLGDPIEAQALLATYGRDRDPEQPLWLGSVKSNIGHTQAAAGVAGVIKMVMSMRH 7681 Query: 467 GQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXX 526 G L + + P+ ++ + E + ++ E EWP RRAGVSSFG GTNAH Sbjct: 7682 GVLPRTLHVDAPSSHVDWTEGAVELLTEQTEWPETE-HVRRAGVSSFGISGTNAHVILEQ 7740 Query: 527 XXXXXXXXXXXXG--------PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVG 578 P V+ WV+S +T + +QA +LL V A + DVG Sbjct: 7741 PAKVIQGTVIGGSTPESGVVEPSVVPWVLSGKTPEALRSQAAKLLASVEAELDRPLVDVG 7800 Query: 579 YSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGA 638 SLV RSLFEHRAVV+ D LA + G P SG A G ++ +F GQG+ Sbjct: 7801 SSLVAARSLFEHRAVVLATDADTAARALAALAVGEPDPAAVSGPARTG-RSAALFSGQGS 7859 Query: 639 QWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAV 698 Q LGMGREL +P LD L LREV+WG DA LLN T + QPALFAV Sbjct: 7860 QRLGMGRELYGRFPVFAEALDAVLAVLDGELDGSLREVMWGEDAGLLNETGWTQPALFAV 7919 Query: 699 EVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVM 758 EVAL+RL+ES+G+ P V GHS+GE++AAH++G RGRLMQALP GG M Sbjct: 7920 EVALHRLVESFGVTPDFVAGHSIGEIAAAHIAGVFSLEDAARLVAARGRLMQALPAGGAM 7979 Query: 759 YAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHA 818 AVQA E E+ P L ++VS+AA+NGP SVV+SGA AV V R A+GR+ L VSHA Sbjct: 7980 VAVQATEDEVIPYLSDEVSIAALNGPASVVVSGAEGAVLEVAARFEAEGRKATMLRVSHA 8039 Query: 819 FHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQL-VAEDYGSADYWVRHIREAVRFA 877 FHS LM+PML++FRAVA+ + P IPV+SN+TG L AE+ S +YWVRH+REAVRFA Sbjct: 8040 FHSPLMDPMLDEFRAVAEGLSFAAPVIPVVSNLTGSLATAEELCSPEYWVRHVREAVRFA 8099 Query: 878 DSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXX 937 D V G T F+E+GP G L+++ +ESL V VP LRK+ E Sbjct: 8100 DGVTTLEEQGVTTFLELGPDGVLSAMAQESLTGDEAVTVPLLRKNTAEEAATVAALARLH 8159 Query: 938 XXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 DW+++ AG G +RV LPTYAF H+ FW A Sbjct: 8160 IGGLRIDWSALFAGTGARRVELPTYAFQHQWFWPA 8194 Score = 706 bits (1823), Expect = 0.0 Identities = 416/971 (42%), Positives = 547/971 (56%), Gaps = 40/971 (4%) Query: 26 DSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAH---DVIKSVLGG 82 D+ +V +DLG S+ + + L+ G+ +P V+D P+ + D + L G Sbjct: 1683 DAGQVEAARQFQDLGFDSLTAVELRNGLNSATGLRLPATMVFDYPTPNALADHLSDELLG 1742 Query: 83 DGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPA 142 G + G T++PI ++GMACR+ G V LW ++E A +P Sbjct: 1743 TGDNIPLPTPAGALP---ATTDDPIVIVGMACRYPGGVTSPEDLWRLVSEGADATGPFPV 1799 Query: 143 RRLGAAAADWLGDEQETIY--------------GCFLEDVEGFDNKFFDIPPDEAALMDP 188 R G + + +Y G FL D FD FF + P EA D Sbjct: 1800 NR---------GWDVDNLYDPDPDRPGHTYVRAGGFLHDAGSFDADFFGMSPREALSTDS 1850 Query: 189 QQRLLLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSS 248 QQRLLLE SW A+E AGI P +L+ S TGVF GV DY +L G + + G + Sbjct: 1851 QQRLLLELSWEAVERAGIDPHSLRGSRTGVFAGVMYNDYGTILT--GEEYEAFRGNGSAP 1908 Query: 249 SIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVW 308 S+ + R+SY L + GP++ +DTACSSSLV HLA ++L +GEC LA+ G V+ +P + Sbjct: 1909 SVASGRVSYTLGLEGPAVTVDTACSSSLVGMHLAAQALRTGECTLALAGGVTVMSTPSTF 1968 Query: 309 RGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQ 368 F ++ G +AF ADG+ EG G+++LER SDA R G +LAVL GSAVNQ Sbjct: 1969 VDFSRQRGLAADGRSKAFAEAADGVAWSEGVGMLLLERRSDAIRNGHEILAVLRGSAVNQ 2028 Query: 369 DGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGR 428 DG SNG+ APN +Q V+ A + P ++D VEAHGTGT++GD IEA AL +GR Sbjct: 2029 DGASNGLTAPNGPSQQRVIRQALASGGLSPEDVDVVEAHGTGTTLGDPIEAQALIATYGR 2088 Query: 429 GRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELG 488 R +PL +GS+K NIGH + AAG+AG+IK ++ ++ G L + + P+ ++ + Sbjct: 2089 DRDPERPLWLGSVKSNIGHTQAAAGVAGVIKMIMSMRHGLLPQTLHVDAPSSHVDWDAGA 2148 Query: 489 LAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXGPG----VLA 544 + ++ E EWP R RRA VSSFG GTNAH GP Sbjct: 2149 VELLTEQTEWPEN-DRVRRAAVSSFGISGTNAHVIIEQPAAGPAPAAPS-GPAEELPAAP 2206 Query: 545 WVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLA 604 W +SA+T + QA RLL V A E D+ YSL+T+RS+F+HRA V+GA R E L Sbjct: 2207 WPLSAKTPEALRDQAARLLAHVEAHPETRPADIAYSLLTSRSVFDHRAAVLGADRTEALR 2266 Query: 605 GLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXE 664 LA + G + +G A GG+T F+F GQG+Q LGMGREL P Sbjct: 2267 ALAALAAGTDDSALLTGTAR-GGRTAFLFSGQGSQRLGMGRELYGRVPVFTEALDAVLAV 2325 Query: 665 LDRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGEL 724 LD L LREV+WG DA+LLN T + QPALFAVEVALYRL+ESWG++P V GHS+GE+ Sbjct: 2326 LDGELEGSLREVMWGEDADLLNETGWTQPALFAVEVALYRLVESWGVKPDFVAGHSIGEI 2385 Query: 725 SAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGP 784 +AAH++G R LMQALP GG M AV+A E E+ PLL VS+AAVNGP Sbjct: 2386 AAAHIAGVLTLADACRLVAARAALMQALPEGGAMIAVEATEDEVLPLLTGDVSIAAVNGP 2445 Query: 785 GSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPA 844 SVV+SGA A V QGRR RL VSHAFHS LM+PML++FR+VA+ + PA Sbjct: 2446 SSVVVSGAEAAALAVAGHFTEQGRRTSRLRVSHAFHSPLMDPMLDEFRSVAEGLSYSAPA 2505 Query: 845 IPVISNVTGQLV-AEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSL 903 IPV+SN+TG L D SADYWVRH+R+AVRFAD V G T FVE+GP G L+++ Sbjct: 2506 IPVVSNLTGTLADPADLCSADYWVRHVRDAVRFADCVGTLGEHGVTTFVELGPDGVLSAM 2565 Query: 904 IEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYA 963 ++S+ + V VP LRKDR E DW S L G RV LPTYA Sbjct: 2566 AQQSVTE-GAVTVPVLRKDRSEEQALVTALCRLYVLGIDADWTSALTVGGAARVDLPTYA 2624 Query: 964 FAHERFWLADR 974 F H FW A R Sbjct: 2625 FQHRWFWPAAR 2635 Score = 703 bits (1815), Expect = 0.0 Identities = 409/953 (42%), Positives = 551/953 (57%), Gaps = 17/953 (1%) Query: 28 AEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGGDGSQR 87 ++++ D RDLG S+ + + L G+ + V+D+P+ + +L Sbjct: 3426 SDIDADRAFRDLGFDSLTAVELRNRLRTATGLRLSATMVFDHPTLSALADHLLT---ELF 3482 Query: 88 SADSDTGCAVLGNGPTNE-PIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLG 146 A+++T V PT++ PI ++GMACRF G V LW ++E AI+++PA R Sbjct: 3483 GAEAETLTPVTLLPPTDDDPIVIVGMACRFPGDVTSPEDLWRLVSEGTDAISDFPANRGW 3542 Query: 147 AAAADWLGDEQE-----TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAAL 201 + + D + T G FL D FD FF + P EA D QQRLLLETSW A+ Sbjct: 3543 DVDSLYHPDPEHSGTSYTRSGGFLHDAGDFDPDFFGMSPREALATDSQQRLLLETSWEAI 3602 Query: 202 EHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDV 261 E AGI P +L+ S TGVF GV DY LL GG++ + G + S+ + R+SY Sbjct: 3603 ERAGIDPLSLRDSRTGVFAGVMYHDYGSLL--GGKEFEGFQGQGSAGSVASGRVSYTFGF 3660 Query: 262 NGPSLVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG 321 GP++ +DTACSSSLVA H A ++L SGEC LA+ G V+ +P + F +S G Sbjct: 3661 EGPAVTVDTACSSSLVALHWAAQALRSGECSLALAGGVTVMSTPSTFIEFSRQQGLSADG 3720 Query: 322 SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPR 381 +AF ADG+ EG G+++LER SDA R G +LAV+ GSAVNQDG SNG+ APN Sbjct: 3721 RSKAFAESADGVGWSEGVGMLLLERQSDAIRNGHEILAVVRGSAVNQDGASNGLTAPNGP 3780 Query: 382 AQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSI 441 +Q V+ A + ++D VEAHGTGT++GD IEA AL +G+ R +PL +GS+ Sbjct: 3781 SQQRVIRQALASGGLSTGDVDAVEAHGTGTTLGDPIEAQALIATYGQNRTDEQPLWLGSL 3840 Query: 442 KPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAV 501 K NIGH + AAG+AG+IK V+ ++ G L + + P+ ++ + E + ++ E EWP Sbjct: 3841 KSNIGHTQAAAGVAGVIKMVMSMRHGVLPCTLHVDAPSSHVDWTEGAVELLTEQTEWPET 3900 Query: 502 VGRPRRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXG---PGVLAWVVSARTAAGVGAQ 558 R RRA VSSFG GTNAH P V+ ++S ++ + Q Sbjct: 3901 -DRVRRAAVSSFGISGTNAHVILEQPVVAPAPATADVDGAEPAVVPLILSGKSPEALRDQ 3959 Query: 559 AGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGV 618 A RLL+ VR L D+G+SL T+RS F+HRAVV+ GR++ L L + + Sbjct: 3960 AARLLDTVREHTALRPLDLGHSLATSRSAFDHRAVVLATGREDALRALTALADDEANSAA 4019 Query: 619 ASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVW 678 +G G + +F GQG+Q LGMGREL +P LD L LREV+W Sbjct: 4020 VTGRTRSGRRAA-LFSGQGSQRLGMGRELYGRFPVFAEALDAVLAVLDGELEGSLREVMW 4078 Query: 679 GADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXX 738 G DA LLN T + QPALFAVEVALYRL+ESWG+RP V GHS+GE++AAH++G Sbjct: 4079 GEDAGLLNETGWTQPALFAVEVALYRLVESWGVRPDFVAGHSIGEIAAAHIAGVFSLEDA 4138 Query: 739 XXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSV 798 RGRLMQALP GG M AVQA E E+ P L ++VS+AA+NGP SVV+SGA AV Sbjct: 4139 ARLVAARGRLMQALPAGGAMVAVQATEDEVIPYLSDEVSIAALNGPASVVVSGAEGAVLE 4198 Query: 799 VVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQL-VA 857 V R A+GR+ L VSHAFHS LM+ ML++FRAVA+ + P IPV+SN+TG L A Sbjct: 4199 VAARFEAEGRKATMLRVSHAFHSPLMDLMLDEFRAVAETLSFAAPVIPVVSNLTGSLATA 4258 Query: 858 EDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVP 917 E+ S +YWVRH+REAVRFAD V + G T F+E+GP G L+++ +ESL V V Sbjct: 4259 EELCSPEYWVRHVREAVRFADGVSALEAQGVTTFLELGPDGVLSAMAQESLTGDEAVTVA 4318 Query: 918 TLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 LRKDR E DW + AG G RV LPTYAF H +W Sbjct: 4319 LLRKDRDEETAALTALAALHTAGVRLDWNAFFAGTGATRVDLPTYAFQHTTYW 4371 Score = 702 bits (1813), Expect = 0.0 Identities = 412/955 (43%), Positives = 540/955 (56%), Gaps = 31/955 (3%) Query: 37 RDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNPSA----HDVIKSVLGGDGSQRSADSD 92 RDLG S+ + + L G+ + AV+D P+ ++ +LG D + ++ Sbjct: 5507 RDLGFDSLTAVELRNRLGAATGVRLSATAVFDYPTVVALVDHLLTELLGPDAESDAEEAA 5566 Query: 93 TGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADW 152 A+L + +PI ++GMACRF G + LW L E I+++P R D Sbjct: 5567 PAEALLDD----DPIVIVGMACRFPGGITSPEDLWRLLGEGSDVISDFPVNR--GWDVDS 5620 Query: 153 LGDEQE-------TIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAG 205 L D T G FL + FD FF + P EA D QQRLLLE++W A+E AG Sbjct: 5621 LYDPDPAHTGTSYTRSGGFLHNAADFDADFFGMSPREAMATDSQQRLLLESTWEAIERAG 5680 Query: 206 ILPKTLKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPS 265 I P TL+ S TGVF GV + Y L G + + G + S+ + R+SY GP+ Sbjct: 5681 IDPVTLRGSRTGVFAGVMYSGYGTAL--DGDEFEGFQGQGSALSVASGRVSYTFGFEGPA 5738 Query: 266 LVIDTACSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRA 325 + IDTACSS+LVA HLA ++L SGEC LA+ G V+ P+ + F +SP G C+ Sbjct: 5739 MTIDTACSSALVAMHLAAQALRSGECSLALAGGVTVMSIPDTFVEFSRQRGLSPDGRCKP 5798 Query: 326 FDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQIS 385 F ADG+ EG G+++LER SDA R G VLAV+ GSAVNQDG SNG+ APN +Q Sbjct: 5799 FSESADGVGWSEGVGMLLLERQSDAIRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQR 5858 Query: 386 VLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNI 445 V+ A + ++D VEAHGTGT++GD IEA AL +G+ R +PL++GS+K NI Sbjct: 5859 VIRQALASGGLSTGDVDAVEAHGTGTTLGDPIEAQALLATYGQNRPEDRPLLLGSVKSNI 5918 Query: 446 GHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRP 505 GH + AAG AG+IK V+ +Q G L S P+ ++ ++ + ++ E EWP R Sbjct: 5919 GHTQAAAGAAGVIKMVMAMQHGVLPRSLNISEPSSHVDWSAGAVELLTEQTEWPET-DRV 5977 Query: 506 RRAGVSSFGFGGTNAHXXXXXXXXXXXXXXXXXG---------PGVLAWVVSARTAAGVG 556 RRAGVSSFG GTNAH P V+ WV+S +T + Sbjct: 5978 RRAGVSSFGISGTNAHVILEQPAKVIQGTVVAASAAPGPDVVEPAVVPWVLSGKTPEALR 6037 Query: 557 AQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGV 616 QA RLL V DV SL T RS F HR VV+ +E + LA + +G P Sbjct: 6038 DQAARLLATVTEEPAPRPVDVALSLATQRSQFAHRGVVLAGEHEETVRALAALADGEPHS 6097 Query: 617 GVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREV 676 V +G + G+ +F GQG+Q LGMGREL +P LD L LREV Sbjct: 6098 SVTTGT-VSSGRRAALFSGQGSQRLGMGRELYGRFPVFAEALDAVLAVLDGELGGSLREV 6156 Query: 677 VWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXX 736 +WG DA LLN T + QPALFAVEVALYRL+ESWG+RP V GHS+GE++AAH++G Sbjct: 6157 MWGEDAGLLNETGWTQPALFAVEVALYRLVESWGVRPDFVAGHSIGEIAAAHIAGVFSLE 6216 Query: 737 XXXXXXXMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAV 796 RGRLMQALP GG M AVQA E E+ P L + VS+AA+NGP SVV+SG +AV Sbjct: 6217 DAARLVAARGRLMQALPAGGAMVAVQATEDEVVPHLSDGVSIAALNGPTSVVVSGVEDAV 6276 Query: 797 SVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQL- 855 V R A+GR+ RL VSHAFHS LM+PML++FRAVA+ + P IPV+SN+TG L Sbjct: 6277 LEVAARFEAEGRKTTRLRVSHAFHSPLMDPMLDEFRAVAEGLSFAAPVIPVVSNLTGSLA 6336 Query: 856 VAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVA 915 AE+ S +YWVRH+REAVRFAD V + G T F+E+GP G L+++ +ESL V Sbjct: 6337 TAEELCSPEYWVRHVREAVRFADGVAALEAQGVTTFLELGPDGVLSAMAQESLTGDETVT 6396 Query: 916 VPTLRKDRPEPFXXXXXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFW 970 +P LRKDR E DWA LA G + V LPTYAF H FW Sbjct: 6397 IPLLRKDRDEETAALTALGRLHATGTRVDWAGFLAPAGARTVDLPTYAFQHRPFW 6451 Score = 688 bits (1776), Expect = 0.0 Identities = 391/874 (44%), Positives = 514/874 (58%), Gaps = 23/874 (2%) Query: 105 EPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARR---LGAAAADWLGDEQETIY 161 EPIAV+G+ CRF G V LW+ +AE + I +P R L A G + Sbjct: 35 EPIAVVGIGCRFPGGVVSPEDLWELVAEGRDVIGPFPTDRGWDLDRLAGGGEGSSLAQVG 94 Query: 162 GCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVG 221 G FL+D GFD FF I P EA MDPQQR+LLE +W ALE AGI P L+ S TGVF+G Sbjct: 95 G-FLDDAAGFDPGFFGISPREAVAMDPQQRILLEIAWEALERAGIDPSALRGSRTGVFMG 153 Query: 222 VSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHL 281 + DY ++ ++ TG ++S+I+ RLSYFL GP++ +DT CSSSLV+ HL Sbjct: 154 TTGQDYGEVIKASDEDAEVYSTTGHAASVISGRLSYFLGAEGPAVTVDTGCSSSLVSLHL 213 Query: 282 ARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGV 341 A ++L GEC LA+ G +V+ +P + F ++ G C+ F ADG EG G+ Sbjct: 214 AAQALRGGECSLALAGGASVMATPHPFIAFTSQSGLAADGRCKPFSDDADGTGWAEGAGL 273 Query: 342 VVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEI 401 +L RLSDA+R GR VLAVL GSA+NQDG SNG+ APN +Q V+ A A + +++ Sbjct: 274 FILMRLSDAQREGRKVLAVLRGSALNQDGASNGLTAPNGPSQQRVIRQALAHAGLQASDV 333 Query: 402 DYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTV 461 D VEAHGTGT +GD IEA AL +G+ R+ +PL++GS+K NIGH + A+G AG+IK + Sbjct: 334 DAVEAHGTGTPLGDPIEAQALLATYGQNRE--RPLLLGSVKSNIGHAQAASGAAGVIKMI 391 Query: 462 LMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSFGFGGTNAH 521 + +Q G L S E P N+ + + +++ +WP GR RRAGVSSFG GTNAH Sbjct: 392 MAIQHGVLPRSLHAERPTSNVDWTAGAVELLDRAVDWPE-TGRARRAGVSSFGISGTNAH 450 Query: 522 XXXXXXXXXXXXXXXXXG--PGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGY 579 P ++ W +S RTAA + AQ RL + + D D+G+ Sbjct: 451 LILEQAPTAPERPAPDPAARPALVPWTLSGRTAAALDAQRERLAAHLESHPGADPLDIGF 510 Query: 580 SLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQ 639 +L R+ FEHRAV++ AG D A E+ G ++ G + +F GQG+Q Sbjct: 511 ALADGRATFEHRAVLLCAGTDASAA--TEIAHG----------SVDDGASAVLFSGQGSQ 558 Query: 640 WLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALFAVE 699 LGMGREL A +P LDRH RPLREVVWG+DAELLN T + QPALFAVE Sbjct: 559 RLGMGRELHARFPVFAEAFDEIAALLDRHTDRPLREVVWGSDAELLNETGWTQPALFAVE 618 Query: 700 VALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGGVMY 759 VALYRL+ S G+ P V GHS+GE++AAHV+G R RLMQ LP GG M Sbjct: 619 VALYRLVSSLGVTPDYVGGHSIGEIAAAHVAGVLSLEDACALVAARARLMQELPRGGAML 678 Query: 760 AVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAF 819 AV+A E+E+ P L E+VS+A+VNGP SVV++G + V+ + AQ R+ RL VSHAF Sbjct: 679 AVRATEEEVAPHLTERVSIASVNGPSSVVVAGDEDEVAAIAAHFEAQDRKTTRLRVSHAF 738 Query: 820 HSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLV-AEDYGSADYWVRHIREAVRFAD 878 HS LM+PMLE+FR VA + P IPV+SN+TG + D +ADYWVRH+REAVRFAD Sbjct: 739 HSPLMDPMLEEFRRVARGLTYHEPRIPVVSNLTGAIADPADLCTADYWVRHVREAVRFAD 798 Query: 879 SVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXXXX 938 V G T +EVGP G L+++ +ESL + VP LRKDRPE Sbjct: 799 GVTTLAGRGVTTLLEVGPDGVLSAMAQESLPE-GTTGVPLLRKDRPEEESALTGLARVHV 857 Query: 939 XXXXXDWASVLAGCGGQRVGLPTYAFAHERFWLA 972 WA + G R LPTY F ++R W A Sbjct: 858 RGLTVRWARLFDSAGAGRADLPTYPFQNQRVWPA 891 Score = 89.7 bits (221), Expect = 5e-15 Identities = 64/157 (40%), Positives = 80/157 (50%), Gaps = 17/157 (10%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L E++ A+L +V E A VLG G +D +AF D G SL+AVELRNRL Sbjct: 5467 RLTRLQRTERRDALLTLVREQAALVLGHSGGGGIDPSRAFRDLGFDSLTAVELRNRLGAA 5526 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDD 2141 TGV LSAT FDYPT L DHLL+ L G E D +A +A DDD Sbjct: 5527 TGVRLSATAVFDYPTVVALVDHLLTEL-----LGPDAESDAEEA------APAEALLDDD 5575 Query: 2142 GWQIVALAANGRERMTTPVPKREWKEVVLLAGGRSDV 2178 IV +A +T+P +++ L G SDV Sbjct: 5576 PIVIVGMACRFPGGITSP------EDLWRLLGEGSDV 5606 Score = 84.7 bits (208), Expect = 1e-13 Identities = 46/97 (47%), Positives = 59/97 (60%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL GL ++ +L +V A VLG + +DA +AF D G SL+AVELRNRL+T Sbjct: 3395 RLAGLDREQRHEVLLDLVRTSAALVLGHAAGSDIDADRAFRDLGFDSLTAVELRNRLRTA 3454 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATP 2118 TG+ LSAT FD+PT + LADHLL+ L TP Sbjct: 3455 TGLRLSATMVFDHPTLSALADHLLTELFGAEAETLTP 3491 Score = 80.9 bits (198), Expect = 2e-12 Identities = 43/87 (49%), Positives = 54/87 (62%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 +L GL A ++ A+L +V A VLG A Q++A + F D G SL+AVELRN L + Sbjct: 1654 QLAGLDAAARREALLGLVRTQIAQVLGHADAGQVEAARQFQDLGFDSLTAVELRNGLNSA 1713 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L AT FDYPTP LADHL L Sbjct: 1714 TGLRLPATMVFDYPTPNALADHLSDEL 1740 Score = 77.0 bits (188), Expect = 3e-11 Identities = 42/87 (48%), Positives = 51/87 (58%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L+ E++ A+L +V A VLG AA +DA F D G SL+AVELRNRL Sbjct: 8975 RLTALTAEERREALLGLVRTQAALVLGHADAASVDAAAQFRDVGFDSLTAVELRNRLSAA 9034 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L+AT FDYP LA HL L Sbjct: 9035 TGLRLTATLVFDYPNAATLASHLHDEL 9061 Score = 76.6 bits (187), Expect = 4e-11 Identities = 46/106 (43%), Positives = 62/106 (58%), Gaps = 2/106 (1%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLG-RDGAAQLDAGQAFSDAGLTSLSAVELRNRLKT 2080 +L GL EQ+ A+L +V A VLG RDG+A + + F + G SL+AVE RNRL T Sbjct: 10747 QLAGLGAQEQEEALLTLVRGQAATVLGHRDGSA-IGRERQFQELGFDSLTAVEFRNRLNT 10805 Query: 2081 LTGVTLSATTAFDYPTPTQLADHLLSHLHHQNPTGATPELDRVDAL 2126 TG+ L AT FDYPTP + +L L +P+GA L ++ L Sbjct: 10806 ATGLRLPATLLFDYPTPADVVRYLRGQLVTDDPSGAGSVLAALEGL 10851 Score = 72.4 bits (176), Expect = 8e-10 Identities = 44/115 (38%), Positives = 64/115 (55%), Gaps = 2/115 (1%) Query: 1010 RLQGLSDAEQQAAVLAMVCEHTAAVLG-RDGAAQLDAGQAFSDAGLTSLSAVELRNRLKT 1068 +L GL EQ+ A+L +V A VLG RDG+A + + F + G SL+AVE RNRL T Sbjct: 10747 QLAGLGAQEQEEALLTLVRGQAATVLGHRDGSA-IGRERQFQELGFDSLTAVEFRNRLNT 10805 Query: 1069 LTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAIVGM 1123 TG+ L AT FDYPTP + +L L + S + + +++ IA + + Sbjct: 10806 ATGLRLPATLLFDYPTPADVVRYLRGQLVTDDPSGAGSVLAALEGLEKAIAALSL 10860 Score = 65.9 bits (159), Expect = 7e-08 Identities = 37/87 (42%), Positives = 49/87 (56%) Query: 2022 RLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTL 2081 RL L E++ ++ +V A VLG A + +AF D G SL++VELRNRL + Sbjct: 7211 RLAVLDAVERREVLVDLVRGQVALVLGHADATAVHPTRAFRDLGFDSLTSVELRNRLNAV 7270 Query: 2082 TGVTLSATTAFDYPTPTQLADHLLSHL 2108 TG+ L AT FDYPT L D +L L Sbjct: 7271 TGLRLPATMVFDYPTVEVLVDFILDEL 7297 >tr|O65933|O65933_MYCTU Tax_Id=1773 (pks8)SubName: Full=Probable polyketide synthase pks8;[Mycobacterium tuberculosis] Length = 1602 Score = 1008 bits (2605), Expect = 0.0 Identities = 519/875 (59%), Positives = 618/875 (70%), Gaps = 8/875 (0%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 ++ EP+A+VGMGCRYPGGV SP LW+LVA G D + +FP DRGWD++ LFDPDPDA GK Sbjct: 31 KLSEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFPADRGWDVDGLFDPDPDACGK 90 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 YTR G F+ DFD GFFGI P EALAMDPQQRLLLE SWEALE GIDP LRGS+T Sbjct: 91 MYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRGSAT 150 Query: 1233 GVFVGIYGDGYGLGTS-QAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 GVF G+ GYG S + + Y TG SVASGR++Y LGL GPA+SVDTACSSSLVAL Sbjct: 151 GVFAGVIHAGYGGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSSLVAL 210 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 HLA SLR+GECDLALAGG TV+ATP+ F+ FSRQR LA DGRCK +A AADGT +SEGA Sbjct: 211 HLAVQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALARDGRCKVYAGAADGTAWSEGA 270 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 G+LV++RL DARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRVI AAL+ A + Sbjct: 271 GVLVVERLVDARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRAALASARLRAV 330 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 +VDVVE HGTGT LGDPIEAQALLATYG+D PLWLGSIKSN+GH+ AAAGVAGVIK Sbjct: 331 EVDVVEGHGTGTMLGDPIEAQALLATYGQDRVE--PLWLGSIKSNIGHTSAAAGVAGVIK 388 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV+AMRH ++P TLH+D P+ HVDWS G V LLT+ R W +V GRPRRAGVSSFG+SGTN Sbjct: 389 MVQAMRHGVMPKTLHVDVPTPHVDWSVGAVSLLTQPRAW-SVHGRPRRAGVSSFGISGTN 447 Query: 1532 AHXXXXXXXXXXXXXXXXXGP---GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 1588 AH P + WV+SAR+ + QA RLL FV A +LD D Sbjct: 448 AHVILEQAPVVESVVPEVASPTAASAVPWVLSARSEQALAGQAQRLLAFVAANPDLDPID 507 Query: 1589 VGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQ 1648 VG+SLV TR++FEHRAVVVGA R LLAGLA + G G GVA G A GKTVFVFPGQ Sbjct: 508 VGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKTVFVFPGQ 567 Query: 1649 GAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALF 1708 GAQW+GMG +L A P ELDRHL PLR V+W D LL +TEFAQPALF Sbjct: 568 GAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEFAQPALF 627 Query: 1709 AVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGG 1768 A+EVAL LL+ WG+ P ++GHSVGE++AAH++G RGRLM LP GG Sbjct: 628 AIEVALATLLQHWGISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMAELPAGG 687 Query: 1769 VMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVS 1828 VM V A E+E+ P+L + ++AAVN P SVV+SG AVS + D A +GRRV RLAVS Sbjct: 688 VMVVVAASEEEVLPVLVDGANLAAVNAPHSVVVSGCEAAVSDIADHFARRGRRVHRLAVS 747 Query: 1829 HAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRF 1888 HAFHS+LMEPML +F +A + +P IP++SNVTGQ+ YG YWV H R VRF Sbjct: 748 HAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSNVTGQMAGAGYGDGQYWVEHARRPVRF 807 Query: 1889 ADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXX 1948 A+ V ++ GATRFVEVGP GGLT+L+E+SL ++V +R++ PE Sbjct: 808 AEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPLGEALSVAMMRREHPEVSSVLGAVATL 867 Query: 1949 XXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DW +V G G+R+ LPTYAF +R+WL Sbjct: 868 FTAGAQMDWPAVF-GSPGRRIELPTYAFQRQRYWL 901 Score = 749 bits (1935), Expect = 0.0 Identities = 417/881 (47%), Positives = 539/881 (61%), Gaps = 25/881 (2%) Query: 104 NEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGD-------E 156 +EP+AV+GM CR+ G V LW+ +A+ + A++++PA R D L D + Sbjct: 33 SEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFPADR--GWDVDGLFDPDPDACGK 90 Query: 157 QETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHT 216 T G FLE FD FF I P EA MDPQQRLLLE SW ALE GI P L+ S T Sbjct: 91 MYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRGSAT 150 Query: 217 GVFVGVSSTDYVRLLFPGGRKPTIWDN---TGGSSSIIANRLSYFLDVNGPSLVIDTACS 273 GVF GV Y GG+ + TG + S+ + R++Y L + GP++ +DTACS Sbjct: 151 GVFAGVIHAGY------GGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACS 204 Query: 274 SSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGM 333 SSLVA HLA +SL SGECDLA+ G V+ +P + F ++ G C+ + ADG Sbjct: 205 SSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALARDGRCKVYAGAADGT 264 Query: 334 VRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKC 393 EG GV+V+ERL DARR G VLA++ GSAVNQDG SNG+ APN +Q V+ +A Sbjct: 265 AWSEGAGVLVVERLVDARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRAALAS 324 Query: 394 ADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAG 453 A + E+D VE HGTGT +GD IEA AL +G+ R +PL +GSIK NIGH AAG Sbjct: 325 ARLRAVEVDVVEGHGTGTMLGDPIEAQALLATYGQDR--VEPLWLGSIKSNIGHTSAAAG 382 Query: 454 IAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSF 513 +AG+IK V ++ G + + +VP P++ ++ ++++ + + W +V GRPRRAGVSSF Sbjct: 383 VAGVIKMVQAMRHGVMPKTLHVDVPTPHVDWSVGAVSLLTQPRAW-SVHGRPRRAGVSSF 441 Query: 514 GFGGTNAHXXXXXXXXXXXXXXXXXGP---GVLAWVVSARTAAGVGAQAGRLLEFVRAGR 570 G GTNAH P + WV+SAR+ + QA RLL FV A Sbjct: 442 GISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSARSEQALAGQAQRLLAFVAANP 501 Query: 571 ELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTV 630 +LD DVG+SLV TR++FEHRAVVVGA R LLAGLA + G G GVA G A GKTV Sbjct: 502 DLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKTV 561 Query: 631 FVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEF 690 FVFPGQGAQW+GMG +L A P ELDRHL PLR V+W D LL +TEF Sbjct: 562 FVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEF 621 Query: 691 AQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQ 750 AQPALFA+EVAL LL+ WG+ P ++GHSVGE++AAH++G RGRLM Sbjct: 622 AQPALFAIEVALATLLQHWGISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMA 681 Query: 751 ALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRV 810 LP GGVM V A E+E+ P+L + ++AAVN P SVV+SG AVS + D A +GRRV Sbjct: 682 ELPAGGVMVVVAASEEEVLPVLVDGANLAAVNAPHSVVVSGCEAAVSDIADHFARRGRRV 741 Query: 811 RRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHI 870 RLAVSHAFHS+LMEPML +F +A + +P IP++SNVTGQ+ YG YWV H Sbjct: 742 HRLAVSHAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSNVTGQMAGAGYGDGQYWVEHA 801 Query: 871 REAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXX 930 R VRFA+ V ++ GATRFVEVGP GGLT+L+E+SL ++V +R++ PE Sbjct: 802 RRPVRFAEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPLGEALSVAMMRREHPEVSSVL 861 Query: 931 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 DW +V G G+R+ LPTYAF +R+WL Sbjct: 862 GAVATLFTAGAQMDWPAVF-GSPGRRIELPTYAFQRQRYWL 901 >tr|C6DS09|C6DS09_MYCTK Tax_Id=478434 SubName: Full=Polyketide synthase pks8;[Mycobacterium tuberculosis] Length = 1602 Score = 1008 bits (2605), Expect = 0.0 Identities = 519/875 (59%), Positives = 618/875 (70%), Gaps = 8/875 (0%) Query: 1113 RIDEPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGK 1172 ++ EP+A+VGMGCRYPGGV SP LW+LVA G D + +FP DRGWD++ LFDPDPDA GK Sbjct: 31 KLSEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFPADRGWDVDGLFDPDPDACGK 90 Query: 1173 TYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSST 1232 YTR G F+ DFD GFFGI P EALAMDPQQRLLLE SWEALE GIDP LRGS+T Sbjct: 91 MYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRGSAT 150 Query: 1233 GVFVGIYGDGYGLGTS-QAQWYADTGHITSVASGRISYCLGLAGPAISVDTACSSSLVAL 1291 GVF G+ GYG S + + Y TG SVASGR++Y LGL GPA+SVDTACSSSLVAL Sbjct: 151 GVFAGVIHAGYGGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACSSSLVAL 210 Query: 1292 HLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGA 1351 HLA SLR+GECDLALAGG TV+ATP+ F+ FSRQR LA DGRCK +A AADGT +SEGA Sbjct: 211 HLAVQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALARDGRCKVYAGAADGTAWSEGA 270 Query: 1352 GMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGA 1411 G+LV++RL DARR G PVLA++ GSAVNQDGASNGLTAP+GP+QQRVI AAL+ A + Sbjct: 271 GVLVVERLVDARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRAALASARLRAV 330 Query: 1412 DVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVIK 1471 +VDVVE HGTGT LGDPIEAQALLATYG+D PLWLGSIKSN+GH+ AAAGVAGVIK Sbjct: 331 EVDVVEGHGTGTMLGDPIEAQALLATYGQDRVE--PLWLGSIKSNIGHTSAAAGVAGVIK 388 Query: 1472 MVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTN 1531 MV+AMRH ++P TLH+D P+ HVDWS G V LLT+ R W +V GRPRRAGVSSFG+SGTN Sbjct: 389 MVQAMRHGVMPKTLHVDVPTPHVDWSVGAVSLLTQPRAW-SVHGRPRRAGVSSFGISGTN 447 Query: 1532 AHXXXXXXXXXXXXXXXXXGP---GVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGD 1588 AH P + WV+SAR+ + QA RLL FV A +LD D Sbjct: 448 AHVILEQAPVVESVVPEVASPTAASAVPWVLSARSEQALAGQAQRLLAFVAANPDLDPID 507 Query: 1589 VGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQ 1648 VG+SLV TR++FEHRAVVVGA R LLAGLA + G G GVA G A GKTVFVFPGQ Sbjct: 508 VGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKTVFVFPGQ 567 Query: 1649 GAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEFAQPALF 1708 GAQW+GMG +L A P ELDRHL PLR V+W D LL +TEFAQPALF Sbjct: 568 GAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEFAQPALF 627 Query: 1709 AVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQALPGGG 1768 A+EVAL LL+ WG+ P ++GHSVGE++AAH++G RGRLM LP GG Sbjct: 628 AIEVALATLLQHWGISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMAELPAGG 687 Query: 1769 VMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVS 1828 VM V A E+E+ P+L + ++AAVN P SVV+SG AVS + D A +GRRV RLAVS Sbjct: 688 VMVVVAASEEEVLPVLVDGANLAAVNAPHSVVVSGCEAAVSDIADHFARRGRRVHRLAVS 747 Query: 1829 HAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRF 1888 HAFHS+LMEPML +F +A + +P IP++SNVTGQ+ YG YWV H R VRF Sbjct: 748 HAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSNVTGQMAGAGYGDGQYWVEHARRPVRF 807 Query: 1889 ADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXXXXXXXX 1948 A+ V ++ GATRFVEVGP GGLT+L+E+SL ++V +R++ PE Sbjct: 808 AEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPLGEALSVAMMRREHPEVSSVLGAVATL 867 Query: 1949 XXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 1983 DW +V G G+R+ LPTYAF +R+WL Sbjct: 868 FTAGAQMDWPAVF-GSPGRRIELPTYAFQRQRYWL 901 Score = 749 bits (1935), Expect = 0.0 Identities = 417/881 (47%), Positives = 539/881 (61%), Gaps = 25/881 (2%) Query: 104 NEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAAAADWLGD-------E 156 +EP+AV+GM CR+ G V LW+ +A+ + A++++PA R D L D + Sbjct: 33 SEPVAVVGMGCRYPGGVDSPETLWELVAQGRDAVSDFPADR--GWDVDGLFDPDPDACGK 90 Query: 157 QETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHT 216 T G FLE FD FF I P EA MDPQQRLLLE SW ALE GI P L+ S T Sbjct: 91 MYTRRGTFLEHAGDFDAGFFGIGPSEALAMDPQQRLLLEVSWEALERTGIDPTKLRGSAT 150 Query: 217 GVFVGVSSTDYVRLLFPGGRKPTIWDN---TGGSSSIIANRLSYFLDVNGPSLVIDTACS 273 GVF GV Y GG+ + TG + S+ + R++Y L + GP++ +DTACS Sbjct: 151 GVFAGVIHAGY------GGQLSGELEGYGLTGSTLSVASGRVAYVLGLEGPAVSVDTACS 204 Query: 274 SSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGM 333 SSLVA HLA +SL SGECDLA+ G V+ +P + F ++ G C+ + ADG Sbjct: 205 SSLVALHLAVQSLRSGECDLALAGGVTVMATPAAFVEFSRQRALARDGRCKVYAGAADGT 264 Query: 334 VRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKC 393 EG GV+V+ERL DARR G VLA++ GSAVNQDG SNG+ APN +Q V+ +A Sbjct: 265 AWSEGAGVLVVERLVDARRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVIRAALAS 324 Query: 394 ADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAG 453 A + E+D VE HGTGT +GD IEA AL +G+ R +PL +GSIK NIGH AAG Sbjct: 325 ARLRAVEVDVVEGHGTGTMLGDPIEAQALLATYGQDR--VEPLWLGSIKSNIGHTSAAAG 382 Query: 454 IAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVGRPRRAGVSSF 513 +AG+IK V ++ G + + +VP P++ ++ ++++ + + W +V GRPRRAGVSSF Sbjct: 383 VAGVIKMVQAMRHGVMPKTLHVDVPTPHVDWSVGAVSLLTQPRAW-SVHGRPRRAGVSSF 441 Query: 514 GFGGTNAHXXXXXXXXXXXXXXXXXGP---GVLAWVVSARTAAGVGAQAGRLLEFVRAGR 570 G GTNAH P + WV+SAR+ + QA RLL FV A Sbjct: 442 GISGTNAHVILEQAPVVESVVPEVASPTAASAVPWVLSARSEQALAGQAQRLLAFVAANP 501 Query: 571 ELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTV 630 +LD DVG+SLV TR++FEHRAVVVGA R LLAGLA + G G GVA G A GKTV Sbjct: 502 DLDPIDVGWSLVKTRAMFEHRAVVVGADRGALLAGLAALAAGESGAGVAVGRARSVGKTV 561 Query: 631 FVFPGQGAQWLGMGRELCAGYPXXXXXXXXXXXELDRHLARPLREVVWGADAELLNTTEF 690 FVFPGQGAQW+GMG +L A P ELDRHL PLR V+W D LL +TEF Sbjct: 562 FVFPGQGAQWVGMGAQLYAELPLFALAFDAVAEELDRHLRLPLRNVLWEGDEALLTSTEF 621 Query: 691 AQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGXXXXXXXXXXXXMRGRLMQ 750 AQPALFA+EVAL LL+ WG+ P ++GHSVGE++AAH++G RGRLM Sbjct: 622 AQPALFAIEVALATLLQHWGISPDFLIGHSVGEIAAAHLAGVLSLTDAAGLVAARGRLMA 681 Query: 751 ALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRV 810 LP GGVM V A E+E+ P+L + ++AAVN P SVV+SG AVS + D A +GRRV Sbjct: 682 ELPAGGVMVVVAASEEEVLPVLVDGANLAAVNAPHSVVVSGCEAAVSDIADHFARRGRRV 741 Query: 811 RRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHI 870 RLAVSHAFHS+LMEPML +F +A + +P IP++SNVTGQ+ YG YWV H Sbjct: 742 HRLAVSHAFHSLLMEPMLAEFTRIAAGISVSKPRIPLVSNVTGQMAGAGYGDGQYWVEHA 801 Query: 871 REAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFXXX 930 R VRFA+ V ++ GATRFVEVGP GGLT+L+E+SL ++V +R++ PE Sbjct: 802 RRPVRFAEGVQLLNAVGATRFVEVGPGGGLTALVEQSLPLGEALSVAMMRREHPEVSSVL 861 Query: 931 XXXXXXXXXXXXXDWASVLAGCGGQRVGLPTYAFAHERFWL 971 DW +V G G+R+ LPTYAF +R+WL Sbjct: 862 GAVATLFTAGAQMDWPAVF-GSPGRRIELPTYAFQRQRYWL 901 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.319 0.135 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 17,199,674,834 Number of extensions: 738695494 Number of successful extensions: 1996490 Number of sequences better than 10.0: 14849 Number of HSP's gapped: 1887868 Number of HSP's successfully gapped: 38043 Length of query: 2414 Length of database: 3,846,993,858 Length adjustment: 154 Effective length of query: 2260 Effective length of database: 2,110,612,596 Effective search space: 4769984466960 Effective search space used: 4769984466960 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 89 (38.9 bits)