BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_1716
         (339 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

sp|B2HIH1|LEU3_MYCMM Tax_Id=216594 (leuB)RecName: Full=3-isoprop...   585   e-165
sp|A0PPY6|LEU3_MYCUA Tax_Id=362242 (leuB)RecName: Full=3-isoprop...   583   e-164
sp|P95313|LEU3_MYCTU Tax_Id=1773 (leuB)RecName: Full=3-isopropyl...   522   e-146
sp|A5U706|LEU3_MYCTA Tax_Id=419947 (leuB)RecName: Full=3-isoprop...   522   e-146
tr|C6DW54|C6DW54_MYCTK Tax_Id=478434 SubName: Full=3-isopropylma...   522   e-146
tr|A5WRP8|A5WRP8_MYCTF Tax_Id=336982 SubName: Full=3-isopropylma...   522   e-146
tr|A4KKQ1|A4KKQ1_MYCTU Tax_Id=395095 SubName: Full=3-isopropylma...   522   e-146
tr|A2VLW6|A2VLW6_MYCTU Tax_Id=348776 SubName: Full=3-isopropylma...   522   e-146
sp|C1AGB0|LEU3_MYCBT Tax_Id=561275 (leuB)RecName: Full=3-isoprop...   520   e-145
sp|A1KMY9|LEU3_MYCBP Tax_Id=410289 (leuB)RecName: Full=3-isoprop...   520   e-145
sp|P94929|LEU3_MYCBO Tax_Id=1765 (leuB)RecName: Full=3-isopropyl...   520   e-145
sp|Q73VI1|LEU3_MYCPA Tax_Id=1770 (leuB)RecName: Full=3-isopropyl...   509   e-142
sp|A0QJC2|LEU3_MYCA1 Tax_Id=243243 (leuB)RecName: Full=3-isoprop...   509   e-142
sp|A1T6Z4|LEU3_MYCVP Tax_Id=350058 (leuB)RecName: Full=3-isoprop...   503   e-140
sp|A4TE12|LEU3_MYCGI Tax_Id=350054 (leuB)RecName: Full=3-isoprop...   503   e-140
sp|Q1BAR4|LEU3_MYCSS Tax_Id=164756 (leuB)RecName: Full=3-isoprop...   500   e-139
sp|A1UE98|LEU3_MYCSK Tax_Id=189918 (leuB)RecName: Full=3-isoprop...   500   e-139
sp|A3PXQ2|LEU3_MYCSJ Tax_Id=164757 (leuB)RecName: Full=3-isoprop...   500   e-139
sp|O33117|LEU3_MYCLE Tax_Id=1769 (leuB)RecName: Full=3-isopropyl...   497   e-139
sp|B8ZS15|LEU3_MYCLB Tax_Id=561304 (leuB)RecName: Full=3-isoprop...   497   e-139
tr|A0QUY3|A0QUY3_MYCS2 Tax_Id=246196 (leuB)SubName: Full=3-isopr...   492   e-137
tr|B1MDR0|B1MDR0_MYCA9 Tax_Id=561007 SubName: Full=3-isopropylma...   463   e-128
sp|Q5YRX2|LEU3_NOCFA Tax_Id=37329 (leuB)RecName: Full=3-isopropy...   454   e-126
tr|D0LC42|D0LC42_GORB4 Tax_Id=526226 SubName: Full=3-isopropylma...   446   e-123
sp|C1B2M3|LEU3_RHOOB Tax_Id=632772 (leuB)RecName: Full=3-isoprop...   431   e-119
sp|Q0S2H1|LEU3_RHOSR Tax_Id=101510 (leuB)RecName: Full=3-isoprop...   430   e-118
sp|A4FMQ2|LEU3_SACEN Tax_Id=405948 (leuB)RecName: Full=3-isoprop...   427   e-118
tr|C6WG57|C6WG57_ACTMD Tax_Id=446462 SubName: Full=3-isopropylma...   423   e-116
tr|C7MXE6|C7MXE6_SACVD Tax_Id=471857 SubName: Full=3-isopropylma...   414   e-113
tr|A3TR55|A3TR55_9MICO Tax_Id=313589 SubName: Full=3-isopropylma...   411   e-113
sp|C0ZXM4|LEU3_RHOE4 Tax_Id=234621 (leuB)RecName: Full=3-isoprop...   411   e-113
tr|C3JSJ7|C3JSJ7_RHOER Tax_Id=596309 (leuB)SubName: Full=3-isopr...   409   e-112
tr|C2CMU7|C2CMU7_CORST Tax_Id=525268 (leuB)SubName: Full=3-isopr...   409   e-112
tr|C8XEL3|C8XEL3_NAKMY Tax_Id=479431 SubName: Full=3-isopropylma...   407   e-112
tr|C5V883|C5V883_9CORY Tax_Id=553207 (leuB)SubName: Full=3-isopr...   405   e-111
tr|C0E6S4|C0E6S4_9CORY Tax_Id=566549 SubName: Full=Putative unch...   404   e-110
sp|A8L554|LEU3_FRASN Tax_Id=298653 (leuB)RecName: Full=3-isoprop...   401   e-110
tr|A6W7Q1|A6W7Q1_KINRD Tax_Id=266940 SubName: Full=3-isopropylma...   401   e-110
tr|C2AUD5|C2AUD5_TSUPA Tax_Id=521096 SubName: Full=3-isopropylma...   400   e-109
sp|Q2J6V8|LEU3_FRASC Tax_Id=106370 (leuB)RecName: Full=3-isoprop...   395   e-108
sp|C3PFX5|LEU3_CORA7 Tax_Id=548476 (leuB)RecName: Full=3-isoprop...   394   e-108
tr|C0WFX3|C0WFX3_9CORY Tax_Id=525260 (leuB)SubName: Full=3-isopr...   394   e-108
tr|C6R8R8|C6R8R8_9CORY Tax_Id=553206 (leuB)SubName: Full=3-isopr...   393   e-107
sp|A4QDP9|LEU3_CORGB Tax_Id=340322 (leuB)RecName: Full=3-isoprop...   390   e-106
sp|Q6NHM7|LEU3_CORDI Tax_Id=1717 (leuB)RecName: Full=3-isopropyl...   390   e-106
sp|C5C2I9|LEU3_BEUC1 Tax_Id=471853 (leuB)RecName: Full=3-isoprop...   389   e-106
sp|P94631|LEU3_CORGL Tax_Id=1718 (leuB)RecName: Full=3-isopropyl...   389   e-106
tr|Q0RDJ4|Q0RDJ4_FRAAA Tax_Id=326424 (leuB)SubName: Full=Beta-Is...   389   e-106
tr|A1SM34|A1SM34_NOCSJ Tax_Id=196162 SubName: Full=3-isopropylma...   389   e-106
tr|C1WQ74|C1WQ74_9ACTO Tax_Id=479435 SubName: Full=3-isopropylma...   387   e-105

>sp|B2HIH1|LEU3_MYCMM Tax_Id=216594 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium marinum]
          Length = 339

 Score =  585 bits (1508), Expect = e-165
 Identities = 301/339 (88%), Positives = 301/339 (88%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAIVAGDGIGPE             PGVEKTNYDLGARRFHATGEILPDSVIAELREH
Sbjct: 1   MKLAIVAGDGIGPEVVAQAVKVLDVVQPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRPGRLYPGVKSPLALEPGNPEIDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH
Sbjct: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII
Sbjct: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVS     
Sbjct: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAH 300

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  SRVDRAVEGYLATRGNERLATAAVGERIAAAL
Sbjct: 301 LGLDDAASRVDRAVEGYLATRGNERLATAAVGERIAAAL 339


>sp|A0PPY6|LEU3_MYCUA Tax_Id=362242 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium ulcerans]
          Length = 339

 Score =  583 bits (1502), Expect = e-164
 Identities = 300/339 (88%), Positives = 301/339 (88%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAIVAGDGIGPE             PGVEKTNYDLGARRFHATGEILPDSVIAELREH
Sbjct: 1   MKLAIVAGDGIGPEVVAQAVKILDVVQPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             D+HINLRPGRLYPGVKSPLALEPGNPEIDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDYHINLRPGRLYPGVKSPLALEPGNPEIDF 120

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH
Sbjct: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII
Sbjct: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVS     
Sbjct: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAH 300

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  SRVDRAVEGYLATRGNERLATAAVGERIAAAL
Sbjct: 301 LGLDDTASRVDRAVEGYLATRGNERLATAAVGERIAAAL 339


>sp|P95313|LEU3_MYCTU Tax_Id=1773 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium tuberculosis]
          Length = 336

 Score =  522 bits (1345), Expect = e-146
 Identities = 269/339 (79%), Positives = 283/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|A5U706|LEU3_MYCTA Tax_Id=419947 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium tuberculosis]
          Length = 336

 Score =  522 bits (1345), Expect = e-146
 Identities = 269/339 (79%), Positives = 283/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|C6DW54|C6DW54_MYCTK Tax_Id=478434 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis]
          Length = 336

 Score =  522 bits (1345), Expect = e-146
 Identities = 269/339 (79%), Positives = 283/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|A5WRP8|A5WRP8_MYCTF Tax_Id=336982 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis]
          Length = 336

 Score =  522 bits (1345), Expect = e-146
 Identities = 269/339 (79%), Positives = 283/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|A4KKQ1|A4KKQ1_MYCTU Tax_Id=395095 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis str. Haarlem]
          Length = 336

 Score =  522 bits (1345), Expect = e-146
 Identities = 269/339 (79%), Positives = 283/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>tr|A2VLW6|A2VLW6_MYCTU Tax_Id=348776 SubName:
           Full=3-isopropylmalate dehydrogenase leuB;[Mycobacterium
           tuberculosis C]
          Length = 336

 Score =  522 bits (1345), Expect = e-146
 Identities = 269/339 (79%), Positives = 283/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|C1AGB0|LEU3_MYCBT Tax_Id=561275 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium bovis]
          Length = 336

 Score =  520 bits (1339), Expect = e-145
 Identities = 268/339 (79%), Positives = 282/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLT AG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|A1KMY9|LEU3_MYCBP Tax_Id=410289 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium bovis]
          Length = 336

 Score =  520 bits (1339), Expect = e-145
 Identities = 268/339 (79%), Positives = 282/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLT AG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|P94929|LEU3_MYCBO Tax_Id=1765 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium bovis]
          Length = 336

 Score =  520 bits (1339), Expect = e-145
 Identities = 268/339 (79%), Positives = 282/339 (83%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+AGDGIGPE             PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct: 1   MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP RLYPGV SPL+   GNP IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLT AG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct: 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336


>sp|Q73VI1|LEU3_MYCPA Tax_Id=1770 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium paratuberculosis]
          Length = 336

 Score =  509 bits (1312), Expect = e-142
 Identities = 263/339 (77%), Positives = 276/339 (81%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE             PGV+KT YDLGARR+HATGE+LPDSVI ELR H
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRPGRLYPGV SPLA   GNP+IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVSSPLA---GNPDIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTG GGAIRVGT NEVATEVS NTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGTGGAIRVGTPNEVATEVSQNTAFGVRRVVVDAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAG LW R V E+G +YPDVE+AYQH+DAATI MVTDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGKLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDL+AAVCGGIGLAASGNID TRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLSAAVCGGIGLAASGNIDGTRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE YLATRGNER AT  VGERIAAAL
Sbjct: 298 LGEDAAATRVDRAVERYLATRGNERPATTEVGERIAAAL 336


>sp|A0QJC2|LEU3_MYCA1 Tax_Id=243243 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium avium]
          Length = 336

 Score =  509 bits (1311), Expect = e-142
 Identities = 262/339 (77%), Positives = 276/339 (81%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE             PGV+KT YDLGARR+HATGE+LPDSVI ELR H
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRPGRLYPGV SPLA   GNP+IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVSSPLA---GNPDIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTG GGAIRVGT NEVATEVS NTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGTGGAIRVGTPNEVATEVSQNTAFGVRRVVVDAFERARRRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAG LW R V E+G +YPDVE+AYQH+DAATI MVTDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGKLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDL+AAVCGGIGLAASGNID TRTNPSMFEPVHGSAPDIAGQG+ADPTAAIMSV+     
Sbjct: 238 TDLSAAVCGGIGLAASGNIDGTRTNPSMFEPVHGSAPDIAGQGVADPTAAIMSVALLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVDRAVE YLATRGNER AT  VGERIAAAL
Sbjct: 298 LGEDAAATRVDRAVERYLATRGNERPATTEVGERIAAAL 336


>sp|A1T6Z4|LEU3_MYCVP Tax_Id=350058 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium vanbaalenii]
          Length = 336

 Score =  503 bits (1295), Expect = e-140
 Identities = 255/339 (75%), Positives = 279/339 (82%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M+LA++AGDGIGPE             PGVEKT YDLGAR++H TGE+LPDSV+ EL+ H
Sbjct: 1   MRLAVIAGDGIGPEVITEALKVLDAVLPGVEKTEYDLGARQYHKTGEVLPDSVLEELKGH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSG+             DHHINLRP RLYPGV+SPLA   GNPEIDF
Sbjct: 61  DAILLGAIGDPSVPSGLLERGLLLRIRFELDHHINLRPARLYPGVQSPLA---GNPEIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT +E+ATEVSVNTAFGVRR V+DAF RA +RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPHEIATEVSVNTAFGVRRAVQDAFGRAQQRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLT AGSLWWRTVQ +  EYPDVE+AYQHVDAATIHMVTDPGRFDVIVTDNLFGDII
Sbjct: 178 KNNVLTNAGSLWWRTVQTVAAEYPDVEVAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDAT T+PSMFEPVHGSAPDIAGQGIADPTAA+MSVS     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATLTHPSMFEPVHGSAPDIAGQGIADPTAAVMSVSLLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVD+AV  +LATRG+E+L+TAAVGERI   L
Sbjct: 298 MAEVDAAARVDKAVAEHLATRGDEKLSTAAVGERILGKL 336


>sp|A4TE12|LEU3_MYCGI Tax_Id=350054 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium gilvum]
          Length = 336

 Score =  503 bits (1294), Expect = e-140
 Identities = 255/339 (75%), Positives = 279/339 (82%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++AGDGIGPE             PGVEKT YDLGAR +H TGE+LPDSV+ EL+ H
Sbjct: 1   MKLAVIAGDGIGPEVIGEALRVLDAVVPGVEKTEYDLGARLYHRTGEVLPDSVLDELKGH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPS+PSGV             DHHINLRPGRLYPGV+SPLA   GNPEIDF
Sbjct: 61  DAILLGAIGDPSMPSGVLERGLLLRIRFELDHHINLRPGRLYPGVQSPLA---GNPEIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT +E+ATEVSVNTA+GVRRVV+DAF+RA +RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPHEIATEVSVNTAYGVRRVVQDAFKRAQQRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLT AGSLWWRTVQ +  EYP+VE+AYQHVDAATIHMVTDPGRFDVIVTDNLFGDII
Sbjct: 178 KNNVLTNAGSLWWRTVQAVAAEYPEVEVAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDAT TNPSMFEPVHGSAPDIAGQGIADPTAAIMSVS     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATLTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVD+AV  +LATRG+E+L+T  VG+RI   L
Sbjct: 298 MAEIDAAARVDKAVAEHLATRGDEKLSTTQVGDRILGKL 336


>sp|Q1BAR4|LEU3_MYCSS Tax_Id=164756 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium sp.]
          Length = 336

 Score =  500 bits (1287), Expect = e-139
 Identities = 253/339 (74%), Positives = 276/339 (81%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M LAI+AGDGIGPE             P VEKT YDLGARR+HATGEILPDSV+ EL+ H
Sbjct: 1   MNLAIIAGDGIGPEVIGEAVKVLDAVLPEVEKTTYDLGARRYHATGEILPDSVLEELKVH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP +LY GV  PLA   GNPEIDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRIRFALDHHINLRPAKLYSGVTGPLA---GNPEIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTG GGAIRVGT +EVATEVS+NTAFGVRRVV DAF RA +RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGTGGAIRVGTPHEVATEVSLNTAFGVRRVVEDAFRRAQQRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLTFAG+LWWRTVQE+G EYPDVE+AYQHVD+A IH+VTDPGRFDVIVTDNLFGDI+
Sbjct: 178 KNNVLTFAGALWWRTVQEVGAEYPDVEIAYQHVDSAMIHIVTDPGRFDVIVTDNLFGDIV 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVD+AVE +L++RG++ L TAAVG+RI   L
Sbjct: 298 VGETDAAARVDKAVEAHLSSRGDQELGTAAVGDRIVGLL 336


>sp|A1UE98|LEU3_MYCSK Tax_Id=189918 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium sp.]
          Length = 336

 Score =  500 bits (1287), Expect = e-139
 Identities = 253/339 (74%), Positives = 276/339 (81%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M LAI+AGDGIGPE             P VEKT YDLGARR+HATGEILPDSV+ EL+ H
Sbjct: 1   MNLAIIAGDGIGPEVIGEAVKVLDAVLPEVEKTTYDLGARRYHATGEILPDSVLEELKVH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP +LY GV  PLA   GNPEIDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRIRFALDHHINLRPAKLYSGVTGPLA---GNPEIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTG GGAIRVGT +EVATEVS+NTAFGVRRVV DAF RA +RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGTGGAIRVGTPHEVATEVSLNTAFGVRRVVEDAFRRAQQRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLTFAG+LWWRTVQE+G EYPDVE+AYQHVD+A IH+VTDPGRFDVIVTDNLFGDI+
Sbjct: 178 KNNVLTFAGALWWRTVQEVGAEYPDVEIAYQHVDSAMIHIVTDPGRFDVIVTDNLFGDIV 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVD+AVE +L++RG++ L TAAVG+RI   L
Sbjct: 298 VGETDAAARVDKAVEAHLSSRGDQELGTAAVGDRIVGLL 336


>sp|A3PXQ2|LEU3_MYCSJ Tax_Id=164757 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium sp.]
          Length = 336

 Score =  500 bits (1287), Expect = e-139
 Identities = 253/339 (74%), Positives = 276/339 (81%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M LAI+AGDGIGPE             P VEKT YDLGARR+HATGEILPDSV+ EL+ H
Sbjct: 1   MNLAIIAGDGIGPEVIGEAVKVLDAVLPEVEKTTYDLGARRYHATGEILPDSVLEELKVH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHHINLRP +LY GV  PLA   GNPEIDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRIRFALDHHINLRPAKLYSGVTGPLA---GNPEIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTG GGAIRVGT +EVATEVS+NTAFGVRRVV DAF RA +RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGTGGAIRVGTPHEVATEVSLNTAFGVRRVVEDAFRRAQQRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLTFAG+LWWRTVQE+G EYPDVE+AYQHVD+A IH+VTDPGRFDVIVTDNLFGDI+
Sbjct: 178 KNNVLTFAGALWWRTVQEVGAEYPDVEIAYQHVDSAMIHIVTDPGRFDVIVTDNLFGDIV 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSV+     
Sbjct: 238 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVD+AVE +L++RG++ L TAAVG+RI   L
Sbjct: 298 VGETDAAARVDKAVEAHLSSRGDQELGTAAVGDRIVGLL 336


>sp|O33117|LEU3_MYCLE Tax_Id=1769 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium leprae]
          Length = 336

 Score =  497 bits (1279), Expect = e-139
 Identities = 252/339 (74%), Positives = 277/339 (81%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+ GDGIGPE             PGV+KT YDLGARR+H TGE+LP+SV+AELREH
Sbjct: 1   MKLAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGA+GDPSVPSGV             DHHINLRP RLYPGV S LA   G P+IDF
Sbjct: 61  DAILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLA---GKPDIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTG GGAIRVGT NEVATEVSVNTAFGVRRVV+DAFERA +RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGTGGAIRVGTPNEVATEVSVNTAFGVRRVVQDAFERARQRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLT+AG+LW R VQE+GE+YPDVE+ YQH+DAATI++VT+P RFDVIVTDNLFGDII
Sbjct: 178 KNNVLTYAGTLWCRIVQEVGEKYPDVEVVYQHIDAATIYLVTEPSRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGI LAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMS++     
Sbjct: 238 TDLAAAVCGGIALAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSLALLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +R+D+AV  YLATRGN R +T  VGERIAAAL
Sbjct: 298 LGEDEPAARLDQAVASYLATRGNGRFSTGEVGERIAAAL 336


>sp|B8ZS15|LEU3_MYCLB Tax_Id=561304 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Mycobacterium leprae]
          Length = 336

 Score =  497 bits (1279), Expect = e-139
 Identities = 252/339 (74%), Positives = 277/339 (81%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLAI+ GDGIGPE             PGV+KT YDLGARR+H TGE+LP+SV+AELREH
Sbjct: 1   MKLAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGA+GDPSVPSGV             DHHINLRP RLYPGV S LA   G P+IDF
Sbjct: 61  DAILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLA---GKPDIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTG GGAIRVGT NEVATEVSVNTAFGVRRVV+DAFERA +RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGTGGAIRVGTPNEVATEVSVNTAFGVRRVVQDAFERARQRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           KNNVLT+AG+LW R VQE+GE+YPDVE+ YQH+DAATI++VT+P RFDVIVTDNLFGDII
Sbjct: 178 KNNVLTYAGTLWCRIVQEVGEKYPDVEVVYQHIDAATIYLVTEPSRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGI LAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMS++     
Sbjct: 238 TDLAAAVCGGIALAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSLALLLAH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +R+D+AV  YLATRGN R +T  VGERIAAAL
Sbjct: 298 LGEDEPAARLDQAVASYLATRGNGRFSTGEVGERIAAAL 336


>tr|A0QUY3|A0QUY3_MYCS2 Tax_Id=246196 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Mycobacterium smegmatis]
          Length = 340

 Score =  492 bits (1267), Expect = e-137
 Identities = 250/339 (73%), Positives = 272/339 (80%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           +KLA++AGDGIGPE             PGVEKT YDLGARR+HATGE+L D  I ELR +
Sbjct: 5   LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHH+NLRPGRLYPGV  PL    GNP IDF
Sbjct: 65  DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLV---GNPPIDF 121

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGA+RVGT +EVATEVSVNTAFGV RVVRDAF RA  RRKHLTLVH
Sbjct: 122 VVVREGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVH 181

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVL FAGSLW RTV  + +EYPDVE+AYQH+DAATIHMVTDPGRFDVIVTDNLFGDII
Sbjct: 182 KTNVLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDII 241

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAA+MSV      
Sbjct: 242 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSH 301

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +RVD+AV  +LATRG+E+L+T+AVGERI + L
Sbjct: 302 VGQTEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340


>tr|B1MDR0|B1MDR0_MYCA9 Tax_Id=561007 SubName:
           Full=3-isopropylmalate dehydrogenase
           (Leu3);[Mycobacterium abscessus]
          Length = 337

 Score =  463 bits (1192), Expect = e-128
 Identities = 238/338 (70%), Positives = 267/338 (78%), Gaps = 3/338 (0%)

Query: 2   KLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREHD 61
           KLAI+AGDGIGPE             PGV+KT YDLGARR+ ATGE++PDSV+ ELR HD
Sbjct: 3   KLAIIAGDGIGPEVIGEAVKVLDAVLPGVDKTEYDLGARRYLATGELMPDSVLDELRGHD 62

Query: 62  AILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDFV 121
           AILLGAIGDP+VPSGV             DHHINLRP +LYPGV  PLA   GNP ID V
Sbjct: 63  AILLGAIGDPAVPSGVLERGLLLNTRFALDHHINLRPAKLYPGVTGPLA---GNPAIDLV 119

Query: 122 VVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVHK 181
           VVREGTEGPYTGNGGAIRV T +EVATEVS+NT FGV RVVR+AFERA  R K+LTLVHK
Sbjct: 120 VVREGTEGPYTGNGGAIRVDTPHEVATEVSLNTRFGVERVVRNAFERAEARSKNLTLVHK 179

Query: 182 NNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIIT 241
           NNVL +AG+LW RTV E+  EYPDV+++YQH+DAATIHMVTDPGRFDVIVTDNLFGDIIT
Sbjct: 180 NNVLKYAGTLWTRTVNEVAAEYPDVQVSYQHIDAATIHMVTDPGRFDVIVTDNLFGDIIT 239

Query: 242 DLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXXX 301
           DL AAV GGIGLAASGNID +  NPSMFEPVHGSAPDIAGQGIADPTAAI+SVS      
Sbjct: 240 DLTAAVTGGIGLAASGNIDGSGKNPSMFEPVHGSAPDIAGQGIADPTAAIVSVSLLLDHL 299

Query: 302 XXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                 +RV+RAVE +LATRG E+L+T+A G+RIA+ L
Sbjct: 300 GETEAAARVERAVEQHLATRGEEKLSTSATGDRIASFL 337


>sp|Q5YRX2|LEU3_NOCFA Tax_Id=37329 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Nocardia farcinica]
          Length = 335

 Score =  454 bits (1167), Expect = e-126
 Identities = 236/339 (69%), Positives = 261/339 (76%), Gaps = 4/339 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE             PGVEKT YDLGA+R+HATGEILPDSV+ ELREH
Sbjct: 1   MKLAVIPGDGIGPEVIAEALKVLDVVVPGVEKTEYDLGAKRYHATGEILPDSVLPELREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHH+NLRP RL+ GV+SPLA   G P+IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLRTRFELDHHVNLRPSRLFTGVRSPLA---GAPDIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTG GGAIRV T +EVATEVS NT FG+ RVVR AF +A  RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGTGGAIRVRTPHEVATEVSTNTRFGIERVVRYAFAKAQARRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAGSLW RTV E+G E+P+V +AYQH+DAATIHMVTDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGSLWQRTVDEVGAEFPEVTVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLAAAV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAGQ  ADPTAAI+SVS     
Sbjct: 238 TDLAAAVSGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQSKADPTAAILSVSLLLNH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +R+D AV   LA R     +T  +G+RIAAA+
Sbjct: 298 LGDTEAAARIDAAVAKDLAARSG-TASTVEIGDRIAAAV 335


>tr|D0LC42|D0LC42_GORB4 Tax_Id=526226 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Gordonia bronchialis]
          Length = 337

 Score =  446 bits (1146), Expect = e-123
 Identities = 233/339 (68%), Positives = 258/339 (76%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++AGDGIGPE             P V+ T +DLGARR+H  GE+L D+ +  LREH
Sbjct: 1   MKLAVIAGDGIGPEVIGEALEVLKTVVPEVDTTEFDLGARRYHRNGELLTDADLDSLREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSVPSGV             DHH+NLRP R  PGV +PLA   G+P+IDF
Sbjct: 61  DAILLGAIGDPSVPSGVLERGLLLTMRFALDHHVNLRPSRRLPGVPTPLA---GDPDIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT  EVATEVSVNT FGV RVVR+AFERA +RRKHLTLVH
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPQEVATEVSVNTRFGVERVVRNAFERAAKRRKHLTLVH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVLTFAGSLW R V+EIG E+PDV  AY HVDAATI++VTDPGRFDVIVTDNLFGDII
Sbjct: 178 KTNVLTFAGSLWARAVEEIGTEFPDVTTAYCHVDAATIYLVTDPGRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TD+AAAV GGIGLAASGNIDAT TNPSMFEPVHGSAPDIAGQG ADPTAAI+SV+     
Sbjct: 238 TDIAAAVSGGIGLAASGNIDATGTNPSMFEPVHGSAPDIAGQGKADPTAAILSVALLLDH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                   RV++AV   LA RG   L+TA VG+RI   L
Sbjct: 298 LGESDAARRVEQAVADDLAERGGSTLSTAEVGKRIRERL 336


>sp|C1B2M3|LEU3_RHOOB Tax_Id=632772 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Rhodococcus opacus]
          Length = 336

 Score =  431 bits (1109), Expect = e-119
 Identities = 220/339 (64%), Positives = 257/339 (75%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIG E             P +E T YDLGARR++ATGE+LPD+ +A +REH
Sbjct: 1   MKLAVIPGDGIGVEVTAEALKVLRKLVPDLETTEYDLGARRYNATGELLPDADLAAIREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSV  GV             DHH+NLRP +LYPG KSPLA +P   +IDF
Sbjct: 61  DAILLGAIGDPSVTPGVLERGLLLNMRFALDHHVNLRPSQLYPGSKSPLAAQP---DIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT +E+ATEVS+NT FG  RVVR AF  A  RRKH+TL+H
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPHEIATEVSINTWFGAERVVRYAFALAQTRRKHVTLIH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVL+ AG++W R V+ +  EYPDVE AY H+DAATI+MVTDP RFDVIVTDNLFGDII
Sbjct: 178 KTNVLSNAGAIWTRAVETVSAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLA AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAGQGIADPTAAI+S +     
Sbjct: 238 TDLAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAALLLRH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +R++ AVE  LA+RG+ ++ T+ VG+RIAAAL
Sbjct: 298 LGRDGDAARIETAVEADLASRGDSKVVTSEVGDRIAAAL 336


>sp|Q0S2H1|LEU3_RHOSR Tax_Id=101510 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Rhodococcus sp.]
          Length = 336

 Score =  430 bits (1106), Expect = e-118
 Identities = 219/339 (64%), Positives = 257/339 (75%), Gaps = 3/339 (0%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIG E             P ++ T YDLGARR++ATGE+LPD+ +A +REH
Sbjct: 1   MKLAVIPGDGIGVEVTAEALKVLRKLVPDLQTTEYDLGARRYNATGELLPDADLAAIREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGAIGDPSV  GV             DHH+NLRP +LYPG KSPLA +P   +IDF
Sbjct: 61  DAILLGAIGDPSVTPGVLERGLLLNMRFALDHHVNLRPSQLYPGSKSPLAAQP---DIDF 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
           VVVREGTEGPYTGNGGAIRVGT +E+ATEVS+NT FG  RVVR AF  A  RRKH+TL+H
Sbjct: 118 VVVREGTEGPYTGNGGAIRVGTPHEIATEVSINTWFGAERVVRYAFALAQTRRKHVTLIH 177

Query: 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
           K NVL+ AG++W R V+ +  EYPDVE AY H+DAATI+MVTDP RFDVIVTDNLFGDII
Sbjct: 178 KTNVLSNAGAIWTRAVETVSAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDII 237

Query: 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXX 300
           TDLA AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAGQGIADPTAAI+S +     
Sbjct: 238 TDLAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAALLLRH 297

Query: 301 XXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                  +R++ AVE  LA+RG+ ++ T+ VG+RIAAAL
Sbjct: 298 LGRDGDAARIEAAVEADLASRGDSKVVTSEVGDRIAAAL 336


>sp|A4FMQ2|LEU3_SACEN Tax_Id=405948 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Saccharopolyspora erythraea]
          Length = 347

 Score =  427 bits (1098), Expect = e-118
 Identities = 223/339 (65%), Positives = 255/339 (75%), Gaps = 5/339 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M+LA++ GDGIGPE             P  E T YDLGA R+HATGE+LP+SV+ ELR+H
Sbjct: 1   MRLAVIPGDGIGPEVVAEALKVLGEVVPDTEITRYDLGAARWHATGELLPESVLGELRQH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGA+GDPSVPSG+             DHH+NLRP RLYPGVKSP++ +PG  EID 
Sbjct: 61  DAILLGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPARLYPGVKSPVS-DPG--EIDM 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHLTLV 179
           VVVREGTEGPY GNGG +R  T +E+ATEVS+NTAFGV RVVRDAF RA  R RKHLTLV
Sbjct: 118 VVVREGTEGPYAGNGGLLRKDTTHEIATEVSINTAFGVERVVRDAFARAASRPRKHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVLT AGSLW R V+E+  ++PDV +AYQHVDA TIHMVTDP RFDVIVTDNLFGDI
Sbjct: 178 HKTNVLTHAGSLWSRVVEEVSLQHPDVTVAYQHVDATTIHMVTDPSRFDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           ITDLA A+ GGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQG ADPTAA++SV+    
Sbjct: 238 ITDLAGAITGGIGLAASGNIDATRRNPSMFEPVHGSAPDIAGQGTADPTAAVLSVALLLD 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERL-ATAAVGERIAA 337
                    RV+ AV   LATR +    AT A+G+R+AA
Sbjct: 298 HVGQSEAARRVEAAVAFDLATRDHSAPGATFAIGDRLAA 336


>tr|C6WG57|C6WG57_ACTMD Tax_Id=446462 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Actinosynnema mirum]
          Length = 345

 Score =  423 bits (1088), Expect = e-116
 Identities = 218/339 (64%), Positives = 257/339 (75%), Gaps = 5/339 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M+LA++ GDGIGPE             P  E T YDLGA R+HATGE+LP+SV+ ELR+H
Sbjct: 1   MRLAVIPGDGIGPEVVAEALKVLGEVVPAAEITRYDLGAARWHATGELLPESVLGELRQH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGA+GDPSVPSG+             DHH+NLRP RLYPGV+SP+A +P  PEID 
Sbjct: 61  DAILLGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPARLYPGVRSPIA-DP--PEIDM 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHLTLV 179
           VVVREGTEG Y GNGG +R  T +E+ATEVS+NT+FGV RVVRDAF RA  R RKHLTLV
Sbjct: 118 VVVREGTEGLYAGNGGLLRKDTPHEIATEVSINTSFGVERVVRDAFARAANRPRKHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVLT AGSLW R V+E+  ++PDV +AYQHVDAATIH+VTDPGR+DVIVTDNLFGDI
Sbjct: 178 HKTNVLTHAGSLWSRVVEEVSLQHPDVTVAYQHVDAATIHLVTDPGRYDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TDLAAAV GGIGLAASGN+D TR NPSMFEPVHGSAPDIAGQG+ADPTAA++SV+    
Sbjct: 238 LTDLAAAVTGGIGLAASGNLDVTRRNPSMFEPVHGSAPDIAGQGVADPTAAVLSVALMLD 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERL-ATAAVGERIAA 337
                    R++ +V   LATR +    AT A+G+R+AA
Sbjct: 298 HLGEHESARRIEASVAFDLATRDHASPGATYAIGDRLAA 336


>tr|C7MXE6|C7MXE6_SACVD Tax_Id=471857 SubName:
           Full=3-isopropylmalate dehydrogenase;[Saccharomonospora
           viridis]
          Length = 342

 Score =  414 bits (1063), Expect = e-113
 Identities = 217/335 (64%), Positives = 249/335 (74%), Gaps = 5/335 (1%)

Query: 5   IVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREHDAIL 64
           ++ GDGIGPE             P  E T YDLGA R+HATGE+LP+SV+ ELR+HDAIL
Sbjct: 1   MIPGDGIGPEVVTEALKVLTEVVPNAEITKYDLGASRWHATGELLPESVLNELRQHDAIL 60

Query: 65  LGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDFVVVR 124
           LGA+GDPSVPSG+             DHH+NLRPGRLYPGV+SPLA  PG  E+D VVVR
Sbjct: 61  LGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPGRLYPGVRSPLAA-PG--EVDMVVVR 117

Query: 125 EGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHLTLVHKNN 183
           EGTEGPY GNGG +R  T  E+ATEVSVNTAFG+RRVV DAF RA RR RKHLTLVHK N
Sbjct: 118 EGTEGPYAGNGGLLRKDTEQEIATEVSVNTAFGIRRVVADAFARAERRPRKHLTLVHKTN 177

Query: 184 VLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDL 243
           VL  AGSLW R V+E   ++PDV +AY HVDAATIH+VTDPGRFDVIVTDNLFGDIITDL
Sbjct: 178 VLEHAGSLWSRIVEEESLKHPDVTVAYSHVDAATIHLVTDPGRFDVIVTDNLFGDIITDL 237

Query: 244 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXXXXX 303
            AAV GGIGLAASGN+D TR NPSMFEPVHGSAPDIAGQ +ADPTAA++SV+        
Sbjct: 238 VAAVTGGIGLAASGNLDITRRNPSMFEPVHGSAPDIAGQNLADPTAAVLSVALLLDHLGE 297

Query: 304 XXXXSRVDRAVEGYLATRG-NERLATAAVGERIAA 337
                R++ +V   LATR  N   +T A+G+R+AA
Sbjct: 298 KEAARRIEASVAFDLATRDQNSPGSTQAIGDRLAA 332


>tr|A3TR55|A3TR55_9MICO Tax_Id=313589 SubName:
           Full=3-isopropylmalate dehydrogenase;[Janibacter sp.
           HTCC2649]
          Length = 361

 Score =  411 bits (1057), Expect = e-113
 Identities = 218/345 (63%), Positives = 252/345 (73%), Gaps = 6/345 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPG----VEKTNYDLGARRFHATGEILPDSVIAE 56
           + LA++AGDGIGPE              G    V  T YDLGA+R++ATGE LP+SV+ E
Sbjct: 16  INLAVIAGDGIGPEVVTEGLKVLEAVTGGSGTKVTSTAYDLGAKRWNATGETLPESVLDE 75

Query: 57  LREHDAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNP 116
           LR HD ILLGAIGDPSVPSGV             DH +NLRP +L+PGV+SPLA++   P
Sbjct: 76  LRGHDVILLGAIGDPSVPSGVLERGILLPLRFALDHFVNLRPAKLFPGVESPLAVDRVAP 135

Query: 117 E-IDFVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RK 174
             IDFVVVREGTEGPY GNGGA+R GT +E+ATEVSVNT FGV RVVR+AF RA  R RK
Sbjct: 136 GGIDFVVVREGTEGPYVGNGGALRTGTPHEIATEVSVNTRFGVERVVREAFARAQARPRK 195

Query: 175 HLTLVHKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDN 234
           HLTLVHK+NVLT AG LW RTV E+G E+PDVE+AYQHVDAATI +VTDPGRFDVIVTDN
Sbjct: 196 HLTLVHKHNVLTHAGHLWRRTVDEVGTEFPDVEIAYQHVDAATIFLVTDPGRFDVIVTDN 255

Query: 235 LFGDIITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSV 294
           LFGDIITD+AAA+ GGIGLAASGNI+ T + PSMFEPVHGSAPDIAGQG ADPTA I+SV
Sbjct: 256 LFGDIITDIAAAIAGGIGLAASGNINPTGSAPSMFEPVHGSAPDIAGQGKADPTATILSV 315

Query: 295 SXXXXXXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
           +             RV+ AV   L  RG E   T+A+G+ + A L
Sbjct: 316 AMLLEHLGRTDEAGRVEAAVAADLGARGREVRTTSAIGDAVTARL 360


>sp|C0ZXM4|LEU3_RHOE4 Tax_Id=234621 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Rhodococcus erythropolis]
          Length = 337

 Score =  411 bits (1056), Expect = e-113
 Identities = 211/340 (62%), Positives = 249/340 (73%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIG E             P +E T YDLGARR++ATGE+LP   + ++R+H
Sbjct: 1   MKLAVIPGDGIGVEVTAEALKVLGKLVPDLETTEYDLGARRYNATGELLPADELDQIRQH 60

Query: 61  DAILLGAIGDPSVPS-GVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIGDP + + G+             DHH+NLRP +LYPG  SPLA +P   EID
Sbjct: 61  DAILLGAIGDPRIVAPGILERGLLLNMRFQLDHHVNLRPAQLYPGALSPLAAQP---EID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEGPYTGNGGAIRVGT +E+ATEVS+NT FG  RVVR AF  A  R KHLTL+
Sbjct: 118 FVVVREGTEGPYTGNGGAIRVGTDHEIATEVSINTWFGAERVVRYAFALAQTRSKHLTLI 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL+ AG++W R ++ +G EYPDVE AY H+DAATI+MVTDP RFDVIVTDNLFGDI
Sbjct: 178 HKTNVLSNAGAIWTRAIETVGAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           ITDLA AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAG+GIADPTAAI+S +    
Sbjct: 238 ITDLAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGKGIADPTAAILSAALLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                   +RV+  V   LATRG   ++T  +G+RI AAL
Sbjct: 298 HLGREDDAARVEAVVAADLATRGEGPISTTEIGDRITAAL 337


>tr|C3JSJ7|C3JSJ7_RHOER Tax_Id=596309 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Rhodococcus erythropolis SK121]
          Length = 337

 Score =  409 bits (1052), Expect = e-112
 Identities = 210/340 (61%), Positives = 249/340 (73%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIG E             P +E T YDLGARR++ATGE+LP   + ++R+H
Sbjct: 1   MKLAVIPGDGIGVEVTAEALKVLGKLVPDLETTEYDLGARRYNATGELLPADELDQIRQH 60

Query: 61  DAILLGAIGDPSVPS-GVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIGDP + + G+             DHH+NLRP +LYPG  SPLA +P   EID
Sbjct: 61  DAILLGAIGDPRIVAPGILERGLLLNMRFQLDHHVNLRPAQLYPGALSPLAAQP---EID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEGPYTGNGGAIRVGT +E+ATEVS+NT FG  RVVR AF  A  R KHLTL+
Sbjct: 118 FVVVREGTEGPYTGNGGAIRVGTDHEIATEVSINTWFGAERVVRYAFALAQTRSKHLTLI 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL+ AG++W R ++ +G E+PDVE AY H+DAATI+MVTDP RFDVIVTDNLFGDI
Sbjct: 178 HKTNVLSNAGAIWTRAIETVGAEFPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           ITDLA AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAG+GIADPTAAI+S +    
Sbjct: 238 ITDLAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGKGIADPTAAILSAALLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                   +RV+  V   LATRG   ++T  +G+RI AAL
Sbjct: 298 HLGREDDAARVEAVVAADLATRGEGPISTTEIGDRITAAL 337


>tr|C2CMU7|C2CMU7_CORST Tax_Id=525268 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Corynebacterium striatum ATCC 6940]
          Length = 338

 Score =  409 bits (1051), Expect = e-112
 Identities = 212/340 (62%), Positives = 249/340 (73%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE               +E T YDLGARR+   GE+L D+ +A +REH
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLNAVRDDIETTEYDLGARRYLRNGELLTDADLASIREH 60

Query: 61  DAILLGAIGDPS-VPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG+P  VP G+             DHH+NLRP +LYP   SPLA  PG  EID
Sbjct: 61  DAILLGAIGEPGQVPPGILERGLLLKMRFALDHHVNLRPSKLYPTATSPLA-NPG--EID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG Y GNGG +R GT +EVA+EVS NT FGV RVVRDAFERAM RRKH+TLV
Sbjct: 118 FVVVREGTEGLYCGNGGTLREGTPHEVASEVSQNTRFGVERVVRDAFERAMGRRKHVTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL  AG LW RTV+E+ +EYP+V + Y H+DAATI+MVTDPGR+DVIVTDNLFGDI
Sbjct: 178 HKTNVLVNAGGLWQRTVEEVAKEYPEVTVDYNHIDAATIYMVTDPGRYDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TDLA AV GGIGLAASGNIDA+ TNPSMFEPVHGSAPDIAG+GIADPTAAI+S +    
Sbjct: 238 LTDLAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGKGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                    R++ AV   ++ RG+E+L T  +G+RIAAAL
Sbjct: 298 HIGDETNAVRIEEAVAADVSARGSEQLGTTEIGDRIAAAL 337


>tr|C8XEL3|C8XEL3_NAKMY Tax_Id=479431 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Nakamurella multipartita]
          Length = 340

 Score =  407 bits (1047), Expect = e-112
 Identities = 211/339 (62%), Positives = 246/339 (72%), Gaps = 5/339 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE             P VE   YDLGA R+H TGE+LPDSV+ ELREH
Sbjct: 1   MKLAVIPGDGIGPEVVAEGLKVLRGVVPDVETNEYDLGAARWHRTGELLPDSVLRELREH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGA+GDP+VPSG+             DHH+NLRP RLYPGV  PLA   G+  ID 
Sbjct: 61  DAILLGAVGDPTVPSGILERGLLLRLRFELDHHVNLRPARLYPGVPGPLA---GDKAIDL 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHLTLV 179
           VV+REGTEGPY GNGG +R  T +E+ATEVS+NT FGV RVVRDAFERA RR R+HLTLV
Sbjct: 118 VVLREGTEGPYVGNGGILRKDTPHEIATEVSLNTYFGVERVVRDAFERAARRPRRHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL  +G LW R V+E+  EY DV +AY H+DAA I++VTDPGRFDV+VTDNLFGDI
Sbjct: 178 HKTNVLVHSGQLWSRVVEEVSMEYQDVAVAYCHMDAAMIYLVTDPGRFDVVVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
            TDLAAAV GGIGLAASGN+D +RTNPSMFEPVHGSAPDIAG G ADPTA ++SV+    
Sbjct: 238 FTDLAAAVSGGIGLAASGNLDVSRTNPSMFEPVHGSAPDIAGTGTADPTATVLSVALLLD 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLA-TAAVGERIAA 337
                    RV+ AV   LATR +  +  T A+G+R+AA
Sbjct: 298 HLGLPEAARRVEAAVAFDLATRQSGSVGRTTAIGDRLAA 336


>tr|C5V883|C5V883_9CORY Tax_Id=553207 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Corynebacterium matruchotii ATCC 14266]
          Length = 339

 Score =  405 bits (1042), Expect = e-111
 Identities = 212/340 (62%), Positives = 246/340 (72%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M+LA++ GDGIGPE               ++ T+YDLGARR+ ATGE+L D  +  L+EH
Sbjct: 1   MRLAVIGGDGIGPEVTAEALKVLRACRDDIDTTDYDLGARRYLATGELLTDDDLRSLKEH 60

Query: 61  DAILLGAIGDPS-VPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG P  VP GV             DHH+NLRP +LYP   SPLA  PG  +ID
Sbjct: 61  DAILLGAIGAPGEVPPGVLERGLLLTMRFALDHHVNLRPAKLYPTATSPLA-NPG--DID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG Y GNGG++R  T +EVA+EVS NT FGV RVVRDAFERA  RRKHLTLV
Sbjct: 118 FVVVREGTEGLYCGNGGSLRKNTPHEVASEVSQNTRFGVERVVRDAFERAQHRRKHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL  AG LW RTV E+ +EYPDV + Y H+DAATI+MVTDP R+DVIVTDNLFGDI
Sbjct: 178 HKTNVLVHAGGLWQRTVDEVAQEYPDVTVDYNHIDAATIYMVTDPARYDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TDLA AV GGIGLAASGNIDAT  NPSMFEPVHGSAPDIAGQGIADPTAAI+S +    
Sbjct: 238 LTDLAGAVTGGIGLAASGNIDATGVNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                   +R++ AV   +A RG+E + T AVG+RIAAA+
Sbjct: 298 HLRDEENAARIEAAVAADVAARGDEPIRTVAVGDRIAAAV 337


>tr|C0E6S4|C0E6S4_9CORY Tax_Id=566549 SubName: Full=Putative
           uncharacterized protein;[Corynebacterium matruchotii
           ATCC 33806]
          Length = 339

 Score =  404 bits (1037), Expect = e-110
 Identities = 211/340 (62%), Positives = 246/340 (72%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M+LA++ GDGIGPE               ++ T+YDLGARR+ ATGE+L D  +  L+EH
Sbjct: 1   MRLAVIGGDGIGPEVTAEALKVLRACRDDIDTTDYDLGARRYLATGELLTDDDLRSLKEH 60

Query: 61  DAILLGAIGDPS-VPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG P  VP GV             DHH+NLRP +LYP   SPLA  PG  +ID
Sbjct: 61  DAILLGAIGAPGEVPPGVLERGLLLTMRFALDHHVNLRPAKLYPTATSPLA-NPG--DID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG Y GNGG++R  T +EVA+EVS NT FGV RVVRDAFERA  RRKHLTLV
Sbjct: 118 FVVVREGTEGLYCGNGGSLRKNTPHEVASEVSQNTRFGVERVVRDAFERAQHRRKHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL  AG LW RTV E+ +EYPDV + Y H+DAATI+MVTDP R+DVIVTDNLFGDI
Sbjct: 178 HKTNVLVHAGGLWQRTVDEVAQEYPDVTVDYNHIDAATIYMVTDPARYDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TDLA AV GGIGLAASGNIDAT  NPSMFEPVHGSAPDIAG+GIADPTAAI+S +    
Sbjct: 238 LTDLAGAVTGGIGLAASGNIDATGVNPSMFEPVHGSAPDIAGRGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                   +R++ AV   +A RG+E + T AVG+RIAAA+
Sbjct: 298 HLRDEENAARIEAAVAADVAARGDEPVRTVAVGDRIAAAV 337


>sp|A8L554|LEU3_FRASN Tax_Id=298653 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Frankia sp.]
          Length = 342

 Score =  401 bits (1031), Expect = e-110
 Identities = 209/340 (61%), Positives = 242/340 (71%), Gaps = 7/340 (2%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M+LA++ GDGIGPE             P VE T+YDLGARR+H TGE LPDSV+AELR H
Sbjct: 1   MRLAVIGGDGIGPEVVAEGLRVLRAVHPKVETTDYDLGARRWHETGETLPDSVLAELRGH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGA+GDP VPSGV             DHH+NLRP RLYPGV SPLA   G+P ID 
Sbjct: 61  DAILLGAVGDPGVPSGVLERGLLLRLRFELDHHVNLRPVRLYPGVTSPLA---GDPAIDM 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHLTLV 179
           +VVREGTEGPY G GG +R GT  EVATE S+NT FGV RVVRDAF RA RR R HLTLV
Sbjct: 118 IVVREGTEGPYAGAGGTLRRGTPQEVATEESLNTRFGVERVVRDAFARASRRPRAHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVLT AG LW RTV E+G E+P V + YQHVDAA++  VTDP RFDV+VTDN+FGDI
Sbjct: 178 HKTNVLTKAGDLWARTVAEVGAEFPAVSVDYQHVDAASMFFVTDPARFDVVVTDNMFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TD+ AA+ GGIGLAASGN+D +  NPSMFEPVHGSAPDIAGQG+ADPTA + SV+    
Sbjct: 238 LTDIGAAITGGIGLAASGNLDPSGANPSMFEPVHGSAPDIAGQGLADPTATVASVAMLLD 297

Query: 300 XXXXXXXXSRVDRAVEGYLATR---GNERLATAAVGERIA 336
                   +RV+ AV   LA R   G  R +T  +G+ +A
Sbjct: 298 HLGHADEAARVEGAVAASLAARAAAGGARRSTREIGDDLA 337


>tr|A6W7Q1|A6W7Q1_KINRD Tax_Id=266940 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Kineococcus radiotolerans]
          Length = 362

 Score =  401 bits (1030), Expect = e-110
 Identities = 217/346 (62%), Positives = 250/346 (72%), Gaps = 10/346 (2%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPG---VEKTNYDLGARRFHATGEILPDSVIAEL 57
           ++LA++ GDGIG E              G   V  T YDLGAR +H TGE LPDSV+ EL
Sbjct: 19  LRLAVIPGDGIGQEVTVEALKVLTAVLGGGGRVATTEYDLGARLYHRTGETLPDSVLEEL 78

Query: 58  REHDAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPE 117
           R HDAILLGA+GDPSVPSGV             DHH+NLRP +L+PGV SPL  +PG  E
Sbjct: 79  RGHDAILLGAVGDPSVPSGVLERGLLLKLRFALDHHVNLRPSKLHPGVPSPLG-DPG--E 135

Query: 118 IDFVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHL 176
           IDFVVVREGTEGPY GNGGA+RVGT  E+ATEVSVNTAFGV RVVRDAF RA  R R+ L
Sbjct: 136 IDFVVVREGTEGPYVGNGGALRVGTPQEIATEVSVNTAFGVERVVRDAFARAAARPRRKL 195

Query: 177 TLVHKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLF 236
           TLVHK+NVL  AG LW RTV+ +G E+PDV + Y HVDAATI +VTDP RFDVIVTDNLF
Sbjct: 196 TLVHKHNVLVHAGHLWRRTVEAVGAEFPDVAVDYLHVDAATIFLVTDPARFDVIVTDNLF 255

Query: 237 GDIITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSX 296
           GDI+TDLAAAV GGIGLAASGN++  RT PSMFEPVHGSAPDIAGQ IADPTAA++SVS 
Sbjct: 256 GDILTDLAAAVTGGIGLAASGNVNPDRTTPSMFEPVHGSAPDIAGQQIADPTAAVLSVSL 315

Query: 297 XXXXXXXXXXXSRVDRAVEGYLATRGNERL---ATAAVGERIAAAL 339
                      +RV+ AV   LA R    +   +T+AVG+ +AAA+
Sbjct: 316 LLAHLGRDDLAARVEAAVAADLARRATGEVGTRSTSAVGDALAAAV 361


>tr|C2AUD5|C2AUD5_TSUPA Tax_Id=521096 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Tsukamurella paurometabola DSM 20162]
          Length = 339

 Score =  400 bits (1028), Expect = e-109
 Identities = 210/340 (61%), Positives = 239/340 (70%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE               +E T+YDLG+RR+   GE+L D  +A LREH
Sbjct: 1   MKLAVIGGDGIGPEVVAEALKVLRVVAGDIETTDYDLGSRRYERNGELLTDEDLASLREH 60

Query: 61  DAILLGAIGDP-SVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIGDP  VP GV             DHH+NLRP +L+PGV+SPL   PG  EID
Sbjct: 61  DAILLGAIGDPRKVPPGVLERGLLLKMRFALDHHVNLRPSKLFPGVESPLK-NPG--EID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG YTGNGGAIRVGT +EVA E SVNT FG  RVVR AF  A  RRK LTLV
Sbjct: 118 FVVVREGTEGAYTGNGGAIRVGTPHEVANETSVNTRFGAERVVRYAFALAQTRRKKLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL + G LW RTV E+G E+PDV + Y H+DAATI++VTDP RFDVIVTDNLFGDI
Sbjct: 178 HKTNVLVYGGGLWQRTVDEVGREFPDVAVDYSHIDAATIYLVTDPSRFDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TD A A+ GGIGLAASGNIDAT TNPSMFEPVHGSAPDI GQGIADPTAAI+S +    
Sbjct: 238 LTDEAGAISGGIGLAASGNIDATGTNPSMFEPVHGSAPDIVGQGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                    R++ AV   L  RG+  + T  VG+RIAA L
Sbjct: 298 HLGNEDGAQRIETAVAADLEARGDAPVRTVEVGDRIAATL 337


>sp|Q2J6V8|LEU3_FRASC Tax_Id=106370 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Frankia sp.]
          Length = 342

 Score =  395 bits (1014), Expect = e-108
 Identities = 205/341 (60%), Positives = 244/341 (71%), Gaps = 7/341 (2%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           M+LA++ GDGIGPE             P V+ T YDLGARR+H TGE LPDSV+ ELR H
Sbjct: 1   MRLAVIGGDGIGPEVVAEGLRVLRAVHPKVDTTEYDLGARRWHETGETLPDSVLEELRGH 60

Query: 61  DAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
           DAILLGA+GDP VPSGV             DHH+NLRP RLYPGV+SPLA   G+P ID 
Sbjct: 61  DAILLGAVGDPGVPSGVLERGLLLRLRFEFDHHVNLRPVRLYPGVRSPLA---GDPAIDM 117

Query: 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHLTLV 179
           +VVREGTEGPY G GG +R GT +EVATE S+NT +GV RVVRDAF RA RR R+HLTLV
Sbjct: 118 IVVREGTEGPYAGAGGVLRKGTPHEVATEESLNTRYGVERVVRDAFRRADRRERRHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HKNNVLT AG LW RTV E+  E+PDV + YQHVDAA++  VTDPGRFDV+VTDN+FGDI
Sbjct: 178 HKNNVLTKAGDLWSRTVAEVAPEFPDVRVDYQHVDAASMFFVTDPGRFDVVVTDNMFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TD+ AA+ GGIGLAASGN+D +  +PSMFEPVHGSAPDIAG+ +ADPTA + SV+    
Sbjct: 238 LTDIGAAITGGIGLAASGNLDPSGVHPSMFEPVHGSAPDIAGRQLADPTATVASVAMLLD 297

Query: 300 XXXXXXXXSRVDRAVEGYLATR---GNERLATAAVGERIAA 337
                   ++V+ AV   LA R   G  + +T   GE +AA
Sbjct: 298 HLGHAEEAAKVEAAVASSLADRAAAGAAQPSTRERGEDLAA 338


>sp|C3PFX5|LEU3_CORA7 Tax_Id=548476 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Corynebacterium aurimucosum]
          Length = 339

 Score =  394 bits (1013), Expect = e-108
 Identities = 208/340 (61%), Positives = 243/340 (71%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE               VE T+YDLGARR+   GE+L D+  A LREH
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLRAVRQDVEVTDYDLGARRYLRNGELLSDADFASLREH 60

Query: 61  DAILLGAIGDPS-VPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG P  VP GV             DHH+NLRP +LYP   SPLA  PG  +ID
Sbjct: 61  DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSKLYPTSTSPLA-NPG--DID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG Y GNGG +R GT +EVA+EVS NT FGV RVVRDAF+RAM RRKH+TLV
Sbjct: 118 FVVVREGTEGLYCGNGGTLREGTEHEVASEVSQNTRFGVERVVRDAFQRAMGRRKHVTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL  AG LW RTV E+ +E+P+V + Y H+DAATI+MVTDP R+DVIVTDNLFGDI
Sbjct: 178 HKTNVLVNAGGLWQRTVNEVAQEFPEVTVDYNHIDAATIYMVTDPARYDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TDLA AV GGIGLAASGNIDA+  NPSMFEPVHGSAPDIAG+GIADPTAAI+S +    
Sbjct: 238 LTDLAGAVTGGIGLAASGNIDASGANPSMFEPVHGSAPDIAGKGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                    R++ AV   ++ RG+ +  T  +G+RIAAAL
Sbjct: 298 HLGDEENAVRIEEAVAADVSARGDAQARTTEIGDRIAAAL 337


>tr|C0WFX3|C0WFX3_9CORY Tax_Id=525260 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Corynebacterium accolens ATCC 49725]
          Length = 339

 Score =  394 bits (1012), Expect = e-108
 Identities = 208/340 (61%), Positives = 241/340 (70%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE               +E T+YDLGARR+   GE+L D+ +A LREH
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLRAVRSDIETTDYDLGARRYLRNGELLTDADLASLREH 60

Query: 61  DAILLGAIGDPS-VPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG P  VP GV             DHH+NLRP  LYP   SPLA  PG  EID
Sbjct: 61  DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSILYPTAHSPLA-NPG--EID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG Y GNGG +R GT +EVA+EVS NT FGV RVVRDAF RA +RR HLTLV
Sbjct: 118 FVVVREGTEGLYCGNGGTLREGTPHEVASEVSQNTRFGVERVVRDAFARASQRRNHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL  AG LW RTV+E+  EYP VE+ Y H+DAATI+MVTDP R+DVIVTDNLFGDI
Sbjct: 178 HKTNVLVNAGDLWHRTVEEVSAEYPQVEVDYNHIDAATIYMVTDPARYDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TDLA A+ GGIGLAASGNIDA+  NPSMFEPVHGSAPDIAGQGIADPTAAI+S +    
Sbjct: 238 LTDLAGAITGGIGLAASGNIDASGKNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                    ++++AV   +A RG+  + T  VG+RIA +L
Sbjct: 298 QLGDEGNAQKIEKAVAEDIAKRGDAPIKTVEVGDRIAGSL 337


>tr|C6R8R8|C6R8R8_9CORY Tax_Id=553206 (leuB)SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Corynebacterium tuberculostearicum SK141]
          Length = 339

 Score =  393 bits (1010), Expect = e-107
 Identities = 210/340 (61%), Positives = 240/340 (70%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE               +E T YDLGARR+   GE+L D+ +  LREH
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLRAVRSDIEVTEYDLGARRYLRNGELLTDADLKSLREH 60

Query: 61  DAILLGAIGDPS-VPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG P  VP GV             DHH+NLRP RLYP   SPLA EPG  +ID
Sbjct: 61  DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSRLYPTASSPLA-EPG--DID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG Y GNGG +R GT +EVA+EVS NT FGV RVVRDAF RA +RRKHLTLV
Sbjct: 118 FVVVREGTEGLYCGNGGTLREGTEHEVASEVSQNTRFGVERVVRDAFARAAQRRKHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL  AG LW RTV E+  E+P+V + YQH+DAATI+MVTDP R+DVIVTDNLFGDI
Sbjct: 178 HKKNVLVNAGGLWQRTVNEVAAEFPEVRVDYQHIDAATIYMVTDPARYDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TDLA AV GGIGLAASGNIDA+  NPSMFEPVHGSAPDIAG+GIADPTAAI+S +    
Sbjct: 238 LTDLAGAVTGGIGLAASGNIDASGANPSMFEPVHGSAPDIAGKGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                    R++ AV   +A RG+  L T  VG+RIA  L
Sbjct: 298 HVGDESNAQRIEDAVAQDVAHRGDGPLKTVEVGDRIAQLL 337


>sp|A4QDP9|LEU3_CORGB Tax_Id=340322 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Corynebacterium glutamicum]
          Length = 340

 Score =  390 bits (1002), Expect = e-106
 Identities = 206/341 (60%), Positives = 241/341 (70%), Gaps = 5/341 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE               +E T+YDLGARR+   GE+L D  +A LREH
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLNAVRDDIETTDYDLGARRYLKNGELLTDEDLASLREH 60

Query: 61  DAILLGAIGDP-SVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG P SVP G+             DHH+NLRP +LY GV+SPL   PG  +ID
Sbjct: 61  DAILLGAIGAPGSVPPGILERGLLLKMRFALDHHVNLRPSKLYDGVESPLR-NPG--KID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG YTGNGGAIRVGTA+E+A E SVNT +G  RV+R AFE A  RRK LTLV
Sbjct: 118 FVVVREGTEGAYTGNGGAIRVGTAHEIANETSVNTRYGAERVIRYAFELAQSRRKKLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL   G LW RTV E+ +EYP+V + Y H+DAATI+++TDP RFDVIVTDNLFGDI
Sbjct: 178 HKTNVLVHGGGLWQRTVDEVAKEYPEVAVDYNHIDAATIYLITDPSRFDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TD A AV GGIGLAASGNIDAT TNPSMFEPVHGSAPDIAGQGIADPTAAI+S +    
Sbjct: 238 LTDEAGAVSGGIGLAASGNIDATGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNER-LATAAVGERIAAAL 339
                    R++ A+   +A R N + ++T  VG+RI  AL
Sbjct: 298 HLGDEDNAVRIETAIAADVAGRDNSQPISTTEVGDRIVKAL 338


>sp|Q6NHM7|LEU3_CORDI Tax_Id=1717 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Corynebacterium diphtheriae]
          Length = 339

 Score =  390 bits (1002), Expect = e-106
 Identities = 208/340 (61%), Positives = 238/340 (70%), Gaps = 4/340 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE               +E T+YDLGARR+   GE+L D+ +  LREH
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLNAVRDDIEVTDYDLGARRYLRNGELLADADLVSLREH 60

Query: 61  DAILLGAIGDPS-VPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG P  VP GV             DHH+NLRP +LYP   SPLA  PG  +ID
Sbjct: 61  DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSKLYPTATSPLA-NPG--DID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG Y GNGG +R GT +E+A+EVS NT +GV RVVRDAFERA  R+KHLTLV
Sbjct: 118 FVVVREGTEGLYCGNGGTLREGTPHEIASEVSQNTRYGVERVVRDAFERAQNRKKHLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL  AG LW RTV EI  EYP+V + Y H+DAATI+MVTDP R+DVIVTDNLFGDI
Sbjct: 178 HKTNVLVNAGGLWQRTVNEIATEYPEVTVDYNHIDAATIYMVTDPSRYDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TDLA AV GGIGLAASGNIDAT  NPSMFEPVHGSAPDIAGQGIADPTAAI+S +    
Sbjct: 238 LTDLAGAVTGGIGLAASGNIDATGVNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
                    R++ AV   +A R    + T  VG+RI AAL
Sbjct: 298 HVGDESNAQRIEAAVTYDVAERPAGPVKTVEVGDRIVAAL 337


>sp|C5C2I9|LEU3_BEUC1 Tax_Id=471853 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Beutenbergia cavernae]
          Length = 347

 Score =  389 bits (999), Expect = e-106
 Identities = 209/340 (61%), Positives = 240/340 (70%), Gaps = 8/340 (2%)

Query: 3   LAIVAGDGIGPEXXXXXXXXXXXXXPG----VEKTNYDLGARRFHATGEILPDSVIAELR 58
           LA+VAGDGIGPE              G    V  T YDLGA R+HATGE L D  +A L 
Sbjct: 7   LAVVAGDGIGPEVVAEGLKVLDAALAGTDVTVRTTAYDLGAARWHATGETLTDEDLAALA 66

Query: 59  EHDAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEI 118
           +HDAILLGAIGDP VPSGV             DH++NLRP RLYPGV +PLA      ++
Sbjct: 67  QHDAILLGAIGDPGVPSGVLERGLLLKLRFAFDHYVNLRPSRLYPGVATPLAK---GGDV 123

Query: 119 DFVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERA-MRRRKHLT 177
           DFVVVREGTEGPY GNGGAIRVGT +E+A EVSVNTAFGV RVVRDAF RA  R RK LT
Sbjct: 124 DFVVVREGTEGPYVGNGGAIRVGTPHEIANEVSVNTAFGVERVVRDAFARADARPRKKLT 183

Query: 178 LVHKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFG 237
           LVHK+NVL  AG LW RTV+ +G E+PDV + Y HVDAATI +VTDP RFDV+VTDNLFG
Sbjct: 184 LVHKHNVLVHAGHLWRRTVEAVGAEFPDVAVDYLHVDAATIFLVTDPARFDVVVTDNLFG 243

Query: 238 DIITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXX 297
           DI+TDLAAA+ GGIGLAASGNI+  R  PSMFEPVHGSAPDIAGQG ADPTA ++SV+  
Sbjct: 244 DILTDLAAAITGGIGLAASGNINPDRAFPSMFEPVHGSAPDIAGQGKADPTATVLSVALL 303

Query: 298 XXXXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIAA 337
                     +R+  AVE  +  RG+   +TA VG+ +AA
Sbjct: 304 LEHLGLTEQAARITAAVESDIVERGSAVRSTAEVGDALAA 343


>sp|P94631|LEU3_CORGL Tax_Id=1718 (leuB)RecName:
           Full=3-isopropylmalate dehydrogenase; EC=1.1.1.85;
           AltName: Full=Beta-IPM dehydrogenase; Short=IMDH;
           AltName: Full=3-IPM-DH;[Corynebacterium glutamicum]
          Length = 340

 Score =  389 bits (998), Expect = e-106
 Identities = 206/341 (60%), Positives = 240/341 (70%), Gaps = 5/341 (1%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
           MKLA++ GDGIGPE               +E T+YDLGARR+   GE+L D  +A LREH
Sbjct: 1   MKLAVIGGDGIGPEVTAEALKVLNAVRDDIETTDYDLGARRYLKNGELLTDEDLASLREH 60

Query: 61  DAILLGAIGDP-SVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEID 119
           DAILLGAIG P SVP G+             DHH+NLRP +LY GV+SPL   PG  +ID
Sbjct: 61  DAILLGAIGAPGSVPPGILERGLLLKMRFALDHHVNLRPSKLYDGVESPLR-NPG--KID 117

Query: 120 FVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLV 179
           FVVVREGTEG YTGNGGAIRVGT +E+A E SVNT +G  RV+R AFE A  RRK LTLV
Sbjct: 118 FVVVREGTEGAYTGNGGAIRVGTPHEIANETSVNTRYGAERVIRYAFELAQSRRKKLTLV 177

Query: 180 HKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDI 239
           HK NVL   G LW RTV E+ +EYP+V + Y H+DAATI++VTDP RFDVIVTDNLFGDI
Sbjct: 178 HKTNVLVHGGGLWQRTVDEVAKEYPEVAVDYNHIDAATIYLVTDPSRFDVIVTDNLFGDI 237

Query: 240 ITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXX 299
           +TD A AV GGIGLAASGNIDAT TNPSMFEPVHGSAPDIAGQGIADPTAAI+S +    
Sbjct: 238 LTDEAGAVSGGIGLAASGNIDATGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLR 297

Query: 300 XXXXXXXXSRVDRAVEGYLATRGNER-LATAAVGERIAAAL 339
                    R++ A+   +A R N + ++T  VG+RI  AL
Sbjct: 298 HLGDEDNAVRIETAIAADVAGRDNSQPISTTEVGDRIVKAL 338


>tr|Q0RDJ4|Q0RDJ4_FRAAA Tax_Id=326424 (leuB)SubName:
           Full=Beta-Isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Frankia alni]
          Length = 338

 Score =  389 bits (998), Expect = e-106
 Identities = 204/337 (60%), Positives = 238/337 (70%), Gaps = 7/337 (2%)

Query: 5   IVAGDGIGPEXXXXXXXXXXXXXPGVEKTNYDLGARRFHATGEILPDSVIAELREHDAIL 64
           ++ GDGIGPE             P V+ T YDLGARR+H TGE LPD+V+ ELR HDAIL
Sbjct: 1   MIGGDGIGPEVVAEGLRVLRAVHPKVDTTEYDLGARRWHQTGETLPDAVLEELRGHDAIL 60

Query: 65  LGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEIDFVVVR 124
           LGA+GDP VPSGV             DHH+NLRP RLYPGV SPLA   G+P ID +VVR
Sbjct: 61  LGAVGDPGVPSGVLERGLLLRLRFELDHHVNLRPVRLYPGVASPLA---GDPTIDMIVVR 117

Query: 125 EGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHLTLVHKNN 183
           EGTEGPY G GG +R GT +EVATE S+NT +GV RVVRDAF RA RR R+HLTLVHKNN
Sbjct: 118 EGTEGPYAGAGGVLRRGTPHEVATEESLNTRYGVERVVRDAFRRAARRERRHLTLVHKNN 177

Query: 184 VLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDL 243
           VLT AG LW R V E+  E+PDV + YQHVDAA++  VTDPGRFDVIVTDN+FGDIITD+
Sbjct: 178 VLTKAGDLWSRAVAEVAPEFPDVRVDYQHVDAASMFFVTDPGRFDVIVTDNMFGDIITDI 237

Query: 244 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXXXXXXXX 303
            AA+ GGIGLAASGN+D +  +PSMFEPVHGSAPDIAG+ +ADPTA + SV+        
Sbjct: 238 GAAITGGIGLAASGNLDPSGAHPSMFEPVHGSAPDIAGKQLADPTATVASVAMLLDHLGH 297

Query: 304 XXXXSRVDRAVEGYLATR---GNERLATAAVGERIAA 337
               +RV+ AV   LA R   G   L+T   GE +AA
Sbjct: 298 AEEAARVEAAVAASLADRVGAGAAALSTRERGEDLAA 334


>tr|A1SM34|A1SM34_NOCSJ Tax_Id=196162 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Nocardioides sp.]
          Length = 478

 Score =  389 bits (998), Expect = e-106
 Identities = 211/347 (60%), Positives = 246/347 (70%), Gaps = 14/347 (4%)

Query: 1   MKLAIVAGDGIGPEXXXXXXXXXXXXXPG---VEKTNYDLGARRFHATGEILPDSVIAEL 57
           ++LA++ GDGIGPE             P     E+T YDLGA R+ ATGE+LPDSV+ E+
Sbjct: 132 LRLAVIPGDGIGPEVTAEALKVLEVASPAGVKFEQTRYDLGAERYLATGEVLPDSVLEEI 191

Query: 58  REHDAILLGAIG----DPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEP 113
           REHDAILLGA+G    DP++P G+             DH++NLRP R++PGV SPLA  P
Sbjct: 192 REHDAILLGAVGGKPNDPNLPPGILERGLLLRLRFELDHYVNLRPSRIFPGVASPLA-NP 250

Query: 114 GNPEIDFVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR- 172
           G  E+DFVVVREGTEGPYTGNGGA+RVGT +E+ATEVSVNTAFGV RVVRDAF RA RR 
Sbjct: 251 G--EVDFVVVREGTEGPYTGNGGALRVGTPHEIATEVSVNTAFGVERVVRDAFARAQRRP 308

Query: 173 RKHLTLVHKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVT 232
           RK LTLVHK NVL  AG++WWR  Q++  EYP+V + Y H+DAA I M TDP RFDVIVT
Sbjct: 309 RKKLTLVHKTNVLVNAGAVWWRITQQVAAEYPEVSVDYMHIDAAMIFMTTDPARFDVIVT 368

Query: 233 DNLFGDIITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIM 292
           DNLFGDIITDLAAA+ GGIGLAASGN++  RT PSMFEPVHGSAPDIAGQ  ADPTAAI+
Sbjct: 369 DNLFGDIITDLAAAITGGIGLAASGNVNPDRTAPSMFEPVHGSAPDIAGQQKADPTAAIL 428

Query: 293 SVSXXXXXXXXXXXXSRVDRAVEGYLATR--GNERLATAAVGERIAA 337
           S S            + ++ A    LA R  G  R  TA VGE IAA
Sbjct: 429 SASLLLDHLGYADAAAVIETAAIADLAAREPGAAR-RTADVGEAIAA 474


>tr|C1WQ74|C1WQ74_9ACTO Tax_Id=479435 SubName:
           Full=3-isopropylmalate dehydrogenase;
           EC=1.1.1.85;[Kribbella flavida DSM 17836]
          Length = 349

 Score =  387 bits (994), Expect = e-105
 Identities = 208/339 (61%), Positives = 242/339 (71%), Gaps = 8/339 (2%)

Query: 3   LAIVAGDGIGPEXXXXXXXXXXXXXP--GV--EKTNYDLGARRFHATGEILPDSVIAELR 58
           LA+V GDGIGPE                GV  E+T YDLGARR+HATGE LPD+ + E+R
Sbjct: 9   LAVVGGDGIGPEVTTEALKVLDAVSAVHGVTFERTEYDLGARRWHATGETLPDAELEEIR 68

Query: 59  EHDAILLGAIGDPSVPSGVXXXXXXXXXXXXXDHHINLRPGRLYPGVKSPLALEPGNPEI 118
           +HDAILLGA+GDP+VPSGV             DH++NLRP ++YP V SPLA  PG  E+
Sbjct: 69  KHDAILLGAVGDPTVPSGVLERGLLLKLRFALDHYVNLRPSKIYPSVGSPLA-NPG--EV 125

Query: 119 DFVVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRR-RKHLT 177
           DFVVVREGTEGPY GNGGA+RVGT  E+ATEVSVNTA+GV+RVVRDAF RA  R RK LT
Sbjct: 126 DFVVVREGTEGPYVGNGGALRVGTPAEIATEVSVNTAYGVQRVVRDAFARAQARPRKKLT 185

Query: 178 LVHKNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFG 237
           LVHKNNVL  AG LW RTV  +  E+PD+ + Y HVDAATI +VTDP RFDVIVTDNLFG
Sbjct: 186 LVHKNNVLVHAGHLWKRTVDAVATEFPDIAVDYLHVDAATIFLVTDPARFDVIVTDNLFG 245

Query: 238 DIITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSXX 297
           DIITDLAAA+ GGIGLAASGNI+  RT PSMFEPVHGSAPDIAGQ  ADPTAAI+S +  
Sbjct: 246 DIITDLAAAISGGIGLAASGNINPDRTAPSMFEPVHGSAPDIAGQQKADPTAAILSTALL 305

Query: 298 XXXXXXXXXXSRVDRAVEGYLATRGNERLATAAVGERIA 336
                     + ++ AV   +  R     +TA +G+ IA
Sbjct: 306 CDHLGLTEAAAAIEAAVTADIEERSGAARSTAEIGDAIA 344


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.318    0.137    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 2,310,301,245
Number of extensions: 91999101
Number of successful extensions: 219718
Number of sequences better than 10.0: 4412
Number of HSP's gapped: 206759
Number of HSP's successfully gapped: 4633
Length of query: 339
Length of database: 3,846,993,858
Length adjustment: 138
Effective length of query: 201
Effective length of database: 2,291,015,844
Effective search space: 460494184644
Effective search space used: 460494184644
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 80 (35.4 bits)