BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_1758
         (385 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|B2HIL3|B2HIL3_MYCMM Tax_Id=216594 SubName: Full=Ketoreductase...   776   0.0  
sp|P95140|PHKR_MYCTU Tax_Id=1773 RecName: Full=Phthiodiolone/phe...   665   0.0  
sp|A5U6V9|PHKR_MYCTA Tax_Id=419947 RecName: Full=Phthiodiolone/p...   665   0.0  
sp|A1KMU5|PHKR_MYCBP Tax_Id=410289 RecName: Full=Phthiodiolone/p...   665   0.0  
sp|Q7TXK4|PHKR_MYCBO Tax_Id=1765 RecName: Full=Phthiodiolone/phe...   665   0.0  
tr|C6DWA1|C6DWA1_MYCTK Tax_Id=478434 SubName: Full=Oxidoreductas...   665   0.0  
tr|C1AG66|C1AG66_MYCBT Tax_Id=561275 SubName: Full=Putative oxid...   665   0.0  
tr|A5WRK3|A5WRK3_MYCTF Tax_Id=336982 SubName: Full=Hypothetical ...   665   0.0  
tr|A4KKL1|A4KKL1_MYCTU Tax_Id=395095 SubName: Full=Hypothetical ...   665   0.0  
tr|A2VLS5|A2VLS5_MYCTU Tax_Id=348776 SubName: Full=Putative unch...   665   0.0  
sp|Q9CD85|PHKR_MYCLE Tax_Id=1769 RecName: Full=Phthiodiolone/phe...   657   0.0  
tr|B8ZTY4|B8ZTY4_MYCLB Tax_Id=561304 SubName: Full=Putative oxid...   657   0.0  
sp|Q4VHK1|PHKR_MYCKA Tax_Id=1768 RecName: Full=Phthiodiolone/phe...   621   e-176
tr|A4TAA4|A4TAA4_MYCGI Tax_Id=350054 SubName: Full=Luciferase fa...   566   e-159
sp|A3Q7Z7|PHKR_MYCSJ Tax_Id=164757 RecName: Full=Phthiodiolone/p...   458   e-127
tr|A4T825|A4T825_MYCGI Tax_Id=350054 SubName: Full=Luciferase fa...   217   2e-54
tr|Q744W4|Q744W4_MYCPA Tax_Id=1770 SubName: Full=Putative unchar...   217   2e-54
tr|A0Q8X8|A0Q8X8_MYCA1 Tax_Id=243243 SubName: Full=Putative unch...   213   2e-53
tr|B9L253|B9L253_THERP Tax_Id=309801 SubName: Full=N5,N10-methyl...   213   3e-53
tr|Q1BAS7|Q1BAS7_MYCSS Tax_Id=164756 SubName: Full=Luciferase-li...   209   6e-52
tr|A3PXN9|A3PXN9_MYCSJ Tax_Id=164757 SubName: Full=Luciferase fa...   209   6e-52
tr|A1UE85|A1UE85_MYCSK Tax_Id=189918 SubName: Full=Luciferase fa...   209   6e-52
tr|A4TDK2|A4TDK2_MYCGI Tax_Id=350054 SubName: Full=Luciferase fa...   208   1e-51
tr|O30260|O30260_ARCFU Tax_Id=2234 SubName: Full=Putative unchar...   177   2e-42
tr|C8S627|C8S627_FERPL Tax_Id=589924 SubName: Full=Luciferase-li...   121   1e-25
tr|B3T418|B3T418_9ARCH Tax_Id=455572 SubName: Full=Putative Luci...   119   8e-25
tr|A9A4M7|A9A4M7_NITMS Tax_Id=436308 SubName: Full=Luciferase fa...   116   4e-24
tr|B3T8P7|B3T8P7_9ARCH Tax_Id=455593 SubName: Full=Putative Luci...   115   9e-24
tr|B3TCN1|B3TCN1_9ARCH Tax_Id=455613 SubName: Full=Putative Luci...   114   2e-23
tr|A0RV14|A0RV14_CENSY Tax_Id=46770 SubName: Full=Flavin-depende...   114   3e-23
tr|C8SAR7|C8SAR7_FERPL Tax_Id=589924 SubName: Full=Luciferase-li...   110   3e-22
tr|C8SBQ9|C8SBQ9_FERPL Tax_Id=589924 SubName: Full=Luciferase-li...   108   1e-21
tr|A0B5M9|A0B5M9_METTP Tax_Id=349307 SubName: Full=Methylenetetr...   106   4e-21
tr|O29071|O29071_ARCFU Tax_Id=2234 SubName: Full=N5,N10-methylen...   103   3e-20
tr|C7P5G0|C7P5G0_METFA Tax_Id=573064 SubName: Full=5,10-methylen...   103   3e-20
sp|O29196|MER_ARCFU Tax_Id=2234 (mer)RecName: Full=5,10-methylen...   103   5e-20
tr|C9REM5|C9REM5_METVM Tax_Id=579137 SubName: Full=5,10-methylen...   102   6e-20
sp|Q58929|MER_METJA Tax_Id=2190 (mer)RecName: Full=5,10-methylen...   102   1e-19
tr|B9L2E3|B9L2E3_THERP Tax_Id=309801 SubName: Full=Putative dehy...   101   2e-19
tr|Q12TK2|Q12TK2_METBU Tax_Id=259564 (mer)SubName: Full=Coenzyme...    99   7e-19
tr|A6UV10|A6UV10_META3 Tax_Id=419665 SubName: Full=5,10-methylen...    99   7e-19
tr|C5U4Q8|C5U4Q8_9EURY Tax_Id=573063 SubName: Full=Luciferase-li...    99   9e-19
tr|C1RNB6|C1RNB6_9CELL Tax_Id=446466 SubName: Full=FAD/FMN-depen...    98   2e-18
sp|Q8PZ66|MER_METMA Tax_Id=2209 (mer)RecName: Full=5,10-methylen...    97   3e-18
tr|D1C9H9|D1C9H9_9CHLR Tax_Id=479434 SubName: Full=Putative F420...    96   8e-18
tr|D1C5U9|D1C5U9_9CHLR Tax_Id=479434 SubName: Full=Luciferase-li...    96   8e-18
tr|Q6M159|Q6M159_METMP Tax_Id=39152 (mer)SubName: Full=Coenzyme ...    96   8e-18
tr|A9A8N4|A9A8N4_METM6 Tax_Id=444158 SubName: Full=5,10-methylen...    96   8e-18
tr|A6VI45|A6VI45_METM7 Tax_Id=426368 SubName: Full=5,10-methylen...    96   8e-18
tr|A4G0D2|A4G0D2_METM5 Tax_Id=402880 SubName: Full=Methylenetetr...    96   1e-17

>tr|B2HIL3|B2HIL3_MYCMM Tax_Id=216594 SubName:
           Full=Ketoreductase;[Mycobacterium marinum]
          Length = 385

 Score =  776 bits (2004), Expect = 0.0
 Identities = 384/385 (99%), Positives = 385/385 (100%)

Query: 1   LKKSSGFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEF 60
           +KKSSGFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEF
Sbjct: 1   MKKSSGFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEF 60

Query: 61  LGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLL 120
           LGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLL
Sbjct: 61  LGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLL 120

Query: 121 TRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRN 180
           TRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRN
Sbjct: 121 TRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRN 180

Query: 181 ALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDA 240
           ALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDA
Sbjct: 181 ALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDA 240

Query: 241 GRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTG 300
           GRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTG
Sbjct: 241 GRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTG 300

Query: 301 VQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSL 360
           VQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSL
Sbjct: 301 VQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSL 360

Query: 361 VNPSLRKTVTAVLPHAKVLRGLKKL 385
           VNPSLRKTVTAVLPHAKVLRGLKKL
Sbjct: 361 VNPSLRKTVTAVLPHAKVLRGLKKL 385


>sp|P95140|PHKR_MYCTU Tax_Id=1773 RecName:
           Full=Phthiodiolone/phenolphthiodiolone dimycocerosates
           ketoreductase; EC=1.2.-.-;[Mycobacterium tuberculosis]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>sp|A5U6V9|PHKR_MYCTA Tax_Id=419947 RecName:
           Full=Phthiodiolone/phenolphthiodiolone dimycocerosates
           ketoreductase; EC=1.2.-.-;[Mycobacterium tuberculosis]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>sp|A1KMU5|PHKR_MYCBP Tax_Id=410289 RecName:
           Full=Phthiodiolone/phenolphthiodiolone dimycocerosates
           ketoreductase; EC=1.2.-.-;[Mycobacterium bovis]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>sp|Q7TXK4|PHKR_MYCBO Tax_Id=1765 RecName:
           Full=Phthiodiolone/phenolphthiodiolone dimycocerosates
           ketoreductase; EC=1.2.-.-;[Mycobacterium bovis]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>tr|C6DWA1|C6DWA1_MYCTK Tax_Id=478434 SubName:
           Full=Oxidoreductase;[Mycobacterium tuberculosis]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>tr|C1AG66|C1AG66_MYCBT Tax_Id=561275 SubName: Full=Putative
           oxidoreductase;[Mycobacterium bovis]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>tr|A5WRK3|A5WRK3_MYCTF Tax_Id=336982 SubName: Full=Hypothetical
           oxidoreductase;[Mycobacterium tuberculosis]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>tr|A4KKL1|A4KKL1_MYCTU Tax_Id=395095 SubName: Full=Hypothetical
           oxidoreductase;[Mycobacterium tuberculosis str. Haarlem]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>tr|A2VLS5|A2VLS5_MYCTU Tax_Id=348776 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium tuberculosis C]
          Length = 381

 Score =  665 bits (1717), Expect = 0.0
 Identities = 318/380 (83%), Positives = 356/380 (93%), Gaps = 1/380 (0%)

Query: 6   GFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGA 65
           G R+GFVDA VHSRLPP++ ARSSM A  VMGADSYW+GDHLNALVPRS+AT E+LG+ A
Sbjct: 3   GLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAA 62

Query: 66  RLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRA 125
           + VPK+DANYEPWTMLGNLA G   +RLRLGVCVTD GRRNPAVTAQAAAT+HLLTRGRA
Sbjct: 63  KFVPKIDANYEPWTMLGNLAFGLP-SRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRA 121

Query: 126 ILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDL 185
           ILGIGVGEREGNEPYGVEW+KPVARFEE LATIRALW+SNG L++RESPYFPL NALFDL
Sbjct: 122 ILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDL 181

Query: 186 PPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPM 245
           PPY+GKWPEIWVAAHGPRMLRATGRYADAW+PIV++RP+DYSRALEAVR+AASDAGRDPM
Sbjct: 182 PPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPM 241

Query: 246 SITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLI 305
           SITP+AVRG++TG +RDDV+EAL+SV+VKM ALG+P EAWARHGVEHPMGADF+GVQD+I
Sbjct: 242 SITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDII 301

Query: 306 PQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSL 365
           PQTMD++TVLSY AKVP  L++EVV SGTPDEVIDQVAEWRDHGLRY+++INGSLVNPSL
Sbjct: 302 PQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSL 361

Query: 366 RKTVTAVLPHAKVLRGLKKL 385
           RKTVTAVLPHAKVLRGLKKL
Sbjct: 362 RKTVTAVLPHAKVLRGLKKL 381


>sp|Q9CD85|PHKR_MYCLE Tax_Id=1769 RecName:
           Full=Phthiodiolone/phenolphthiodiolone dimycocerosates
           ketoreductase; EC=1.2.-.-;[Mycobacterium leprae]
          Length = 382

 Score =  657 bits (1694), Expect = 0.0
 Identities = 309/381 (81%), Positives = 357/381 (93%)

Query: 5   SGFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLG 64
           +GFR+GFVDA VH+  PPS+ AR+S+++GAV+GADSYW+GDHLNALVPRSVATP++LG+ 
Sbjct: 2   AGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALVPRSVATPKYLGVA 61

Query: 65  ARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGR 124
           A++VPK+DANYEPWTMLGNLAAGNR+N LRLGVCVTD GRRNPAVTAQAAAT+HLLTRG+
Sbjct: 62  AKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGK 121

Query: 125 AILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFD 184
           A+LGIGVGEREGNEPYGVEW+KPVARF+E LATIRALWDSNG LV+RES +FPL NALFD
Sbjct: 122 AMLGIGVGEREGNEPYGVEWTKPVARFQEALATIRALWDSNGELVSRESQFFPLHNALFD 181

Query: 185 LPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDP 244
           LPPY+GKWPEIWVAAHGPRML+ATGRYADAW+PIV++RPTDYS ALE VR AASDAGRDP
Sbjct: 182 LPPYRGKWPEIWVAAHGPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDP 241

Query: 245 MSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDL 304
           MSITP+AVRG++TG +RDDVDEALDSV+V+M ALG+P EAWARHGVEHPMGADF GVQD+
Sbjct: 242 MSITPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFAGVQDI 301

Query: 305 IPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPS 364
           IPQT+D ETV+SY AKVP  L++EV+ SGTP+EVIDQVAEWRDHGL+YL+VINGSLVN S
Sbjct: 302 IPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSS 361

Query: 365 LRKTVTAVLPHAKVLRGLKKL 385
           LRKTV+A+LPHA+VLRGLKKL
Sbjct: 362 LRKTVSALLPHARVLRGLKKL 382


>tr|B8ZTY4|B8ZTY4_MYCLB Tax_Id=561304 SubName: Full=Putative
           oxidoreductase;[Mycobacterium leprae]
          Length = 382

 Score =  657 bits (1694), Expect = 0.0
 Identities = 309/381 (81%), Positives = 357/381 (93%)

Query: 5   SGFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLG 64
           +GFR+GFVDA VH+  PPS+ AR+S+++GAV+GADSYW+GDHLNALVPRSVATP++LG+ 
Sbjct: 2   AGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALVPRSVATPKYLGVA 61

Query: 65  ARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGR 124
           A++VPK+DANYEPWTMLGNLAAGNR+N LRLGVCVTD GRRNPAVTAQAAAT+HLLTRG+
Sbjct: 62  AKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGK 121

Query: 125 AILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFD 184
           A+LGIGVGEREGNEPYGVEW+KPVARF+E LATIRALWDSNG LV+RES +FPL NALFD
Sbjct: 122 AMLGIGVGEREGNEPYGVEWTKPVARFQEALATIRALWDSNGELVSRESQFFPLHNALFD 181

Query: 185 LPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDP 244
           LPPY+GKWPEIWVAAHGPRML+ATGRYADAW+PIV++RPTDYS ALE VR AASDAGRDP
Sbjct: 182 LPPYRGKWPEIWVAAHGPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDP 241

Query: 245 MSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDL 304
           MSITP+AVRG++TG +RDDVDEALDSV+V+M ALG+P EAWARHGVEHPMGADF GVQD+
Sbjct: 242 MSITPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFAGVQDI 301

Query: 305 IPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPS 364
           IPQT+D ETV+SY AKVP  L++EV+ SGTP+EVIDQVAEWRDHGL+YL+VINGSLVN S
Sbjct: 302 IPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSS 361

Query: 365 LRKTVTAVLPHAKVLRGLKKL 385
           LRKTV+A+LPHA+VLRGLKKL
Sbjct: 362 LRKTVSALLPHARVLRGLKKL 382


>sp|Q4VHK1|PHKR_MYCKA Tax_Id=1768 RecName:
           Full=Phthiodiolone/phenolphthiodiolone dimycocerosates
           ketoreductase; EC=1.2.-.-; Flags:
           Fragment;[Mycobacterium kansasii]
          Length = 367

 Score =  621 bits (1601), Expect = e-176
 Identities = 300/368 (81%), Positives = 330/368 (89%), Gaps = 1/368 (0%)

Query: 18  SRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEP 77
           SR  P  +ARSSM+A  + GADSYW+GDHLN LVPRS+ATPE+LG+ A+LVP VDANYEP
Sbjct: 1   SRFRPGWLARSSMVAATLTGADSYWVGDHLNGLVPRSIATPEYLGIAAKLVPSVDANYEP 60

Query: 78  WTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGN 137
           WTMLGNLA G R  RLRLG+CVTD GRRNPAVTAQAAAT+ LLTRG AILGIGVGEREGN
Sbjct: 61  WTMLGNLAYG-RPKRLRLGICVTDAGRRNPAVTAQAAATLQLLTRGNAILGIGVGEREGN 119

Query: 138 EPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWV 197
           EPYGVEW++PVARFEE LATIRALW+SNG LV+RES YFPL+NA F+LPPY+GKWPEIWV
Sbjct: 120 EPYGVEWTRPVARFEEALATIRALWNSNGELVSRESAYFPLQNAAFELPPYRGKWPEIWV 179

Query: 198 AAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVT 257
           AAHGPRMLRATGRYADAWVPIV++RP DYS ALEAVR AASDAGRDPMSI PSAVRGV+T
Sbjct: 180 AAHGPRMLRATGRYADAWVPIVLVRPGDYSTALEAVRTAASDAGRDPMSIIPSAVRGVIT 239

Query: 258 GWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSY 317
           G  RDDV+EALDSV+VKM ALG+P  AWARHGVEHPMGADF GVQD+IPQTMD +TVLSY
Sbjct: 240 GRDRDDVEEALDSVVVKMTALGVPGTAWARHGVEHPMGADFAGVQDVIPQTMDEQTVLSY 299

Query: 318 TAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAVLPHAK 377
           TAKVPP L++EVV SGTP+EV+DQVA+WRDHGL YLLVINGSLVNPSLRK V A LPHAK
Sbjct: 300 TAKVPPALMKEVVFSGTPEEVVDQVAQWRDHGLEYLLVINGSLVNPSLRKAVAASLPHAK 359

Query: 378 VLRGLKKL 385
           VLRGLKKL
Sbjct: 360 VLRGLKKL 367


>tr|A4TAA4|A4TAA4_MYCGI Tax_Id=350054 SubName: Full=Luciferase
           family protein;[Mycobacterium gilvum]
          Length = 389

 Score =  566 bits (1459), Expect = e-159
 Identities = 276/381 (72%), Positives = 322/381 (84%), Gaps = 1/381 (0%)

Query: 5   SGFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLG 64
           S FR+G +D  V++R+ P+++  ++M+  +  GADS+W+GDH+N+LVPRSVATPE LGL 
Sbjct: 10  SQFRFGLLDGIVNTRVSPTLLPSAAMLTASATGADSFWVGDHINSLVPRSVATPEHLGLA 69

Query: 65  ARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGR 124
           A+LVPKVDA  EPWTMLG+LAA +R  RLR GV VTD  RR+PAVTAQAAAT+HLLTRGR
Sbjct: 70  AKLVPKVDAILEPWTMLGHLAARHR-GRLRFGVGVTDASRRHPAVTAQAAATLHLLTRGR 128

Query: 125 AILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFD 184
           AILGIGVGEREGNEPYGVEW+KPVARF E LATIRALW+S G  VTRES YFPLR+A+FD
Sbjct: 129 AILGIGVGEREGNEPYGVEWTKPVARFVEALATIRALWESGGEPVTRESDYFPLRHAVFD 188

Query: 185 LPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDP 244
           LPPYKG+WPEIWVAAHGPRMLRATGRYAD WVP VI RP DY+RAL+AVR AASD GRDP
Sbjct: 189 LPPYKGRWPEIWVAAHGPRMLRATGRYADGWVPFVISRPADYARALDAVRTAASDNGRDP 248

Query: 245 MSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDL 304
           M+I P+  R VVTG +R DVDEALDSVIVK  AL  PAEAWARHGVEHP+G+DF+GVQDL
Sbjct: 249 MAIVPAVNRTVVTGRTRADVDEALDSVIVKSVALAAPAEAWARHGVEHPLGSDFSGVQDL 308

Query: 305 IPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPS 364
           +PQ +D+E  L+YTA VP  L++E+   GT DEV+DQVAEWRDHGLRYLLVINGS +NP 
Sbjct: 309 VPQMIDKEAALAYTASVPASLMKEICFHGTADEVLDQVAEWRDHGLRYLLVINGSQLNPK 368

Query: 365 LRKTVTAVLPHAKVLRGLKKL 385
           LRK V+A LP+ +VLRGLKKL
Sbjct: 369 LRKGVSATLPYNRVLRGLKKL 389


>sp|A3Q7Z7|PHKR_MYCSJ Tax_Id=164757 RecName:
           Full=Phthiodiolone/phenolphthiodiolone dimycocerosates
           ketoreductase; EC=1.2.-.-;[Mycobacterium sp.]
          Length = 380

 Score =  458 bits (1179), Expect = e-127
 Identities = 225/381 (59%), Positives = 284/381 (74%), Gaps = 2/381 (0%)

Query: 5   SGFRYGFVDAPVHSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLG 64
           +GFR G  D    +R     + R++ +       DS+W+ DHLN L PRS+   ++ G  
Sbjct: 2   TGFRVGVGDGIPAARPAAETMTRANYLGAVANRVDSFWVPDHLNQLFPRSLWKQKYCG-A 60

Query: 65  ARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGR 124
            +L+P+VDA  EPWTMLG++AA NR  RLRLGV VTD GRRNPAVTAQAAAT+HLLTRGR
Sbjct: 61  TKLIPRVDAVMEPWTMLGHIAARNRAGRLRLGVAVTDSGRRNPAVTAQAAATLHLLTRGR 120

Query: 125 AILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFD 184
           AILGIG GEREGNEPYGV+WSKPVARFEE +ATIRALWDS G LV R+SP+FPLR A+FD
Sbjct: 121 AILGIGPGEREGNEPYGVDWSKPVARFEEAMATIRALWDSGGELVNRDSPFFPLRKAIFD 180

Query: 185 LPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDP 244
           LPPY+GKWPEIW+AAHGPRMLRA GRYADA+ P     PT+Y++ L++VR+AASD GRDP
Sbjct: 181 LPPYRGKWPEIWIAAHGPRMLRAAGRYADAYFPSFAHLPTEYAQRLDSVRSAASDVGRDP 240

Query: 245 MSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDL 304
           M+I P+    VVTG +RDDVDEALDS +++   L    + + RHG  HPMGA F+G QDL
Sbjct: 241 MAILPAVQMFVVTGSTRDDVDEALDSELLRAFGLNASDDVFTRHGGRHPMGAGFSGAQDL 300

Query: 305 IPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPS 364
           +P  MD +T LS+ A +PPG+ RE + +GT DEVI Q A+WRD  +RY++++N S +  +
Sbjct: 301 LPHDMDEQTALSHVAVIPPGVTREFLLNGTSDEVIQQAAQWRD-CVRYMVLVNVSFLQRN 359

Query: 365 LRKTVTAVLPHAKVLRGLKKL 385
           LRK + +V P  K++R LKKL
Sbjct: 360 LRKGLMSVKPFNKIVRELKKL 380


>tr|A4T825|A4T825_MYCGI Tax_Id=350054 SubName: Full=Luciferase
           family protein;[Mycobacterium gilvum]
          Length = 372

 Score =  217 bits (553), Expect = 2e-54
 Identities = 125/316 (39%), Positives = 171/316 (54%), Gaps = 12/316 (3%)

Query: 40  SYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLA----AGNRINRLRL 95
           S W+ DH+ +  P S+ TPEF  L         A+  P   L  +A    A      + L
Sbjct: 30  SIWLPDHMVSFWPDSIWTPEFTDLAV-------ASPSPHRHLDGMAVAAAAAVLTENVPL 82

Query: 96  GVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGL 155
              V D  RR+PA  AQ+A T+  L++GR ILG+G GERE   PYG ++  PV RFEE L
Sbjct: 83  ATSVVDTVRRHPASLAQSALTIDHLSKGRFILGLGSGERENILPYGFDFRSPVGRFEEAL 142

Query: 156 ATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAW 215
             IR LWD+ G  V  +  ++ LR+A  D  PY+G+ P IWV A GPR L   GRYAD W
Sbjct: 143 HVIRLLWDTEGP-VDFDGRFYRLRHARLDTEPYEGRRPPIWVGASGPRSLDIAGRYADGW 201

Query: 216 VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKM 275
            P     P DY+  L  VR++A  AGRDP  ITP  ++  + G     + E L + +VK 
Sbjct: 202 WPAGAWTPDDYAEKLTRVRSSAERAGRDPQQITPCFIQVCLMGRDDAALAEILQAPLVKS 261

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTP 335
             L + AE   R G EHPMG D+ G  D+ P  + RE ++ +  +V P ++  +V  GTP
Sbjct: 262 FLLQVSAEVLRRFGFEHPMGPDWNGFHDIDPAVLTRERIVEFLDRVQPEMVLAMVPHGTP 321

Query: 336 DEVIDQVAEWRDHGLR 351
            +V   + ++ D GLR
Sbjct: 322 KQVARVIKDYVDVGLR 337


>tr|Q744W4|Q744W4_MYCPA Tax_Id=1770 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium paratuberculosis]
          Length = 375

 Score =  217 bits (552), Expect = 2e-54
 Identities = 124/316 (39%), Positives = 172/316 (54%), Gaps = 12/316 (3%)

Query: 40  SYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRI----NRLRL 95
           S W+ DH+ +  P S+  PEF  L         A+  P   L  LA    +     R  L
Sbjct: 30  SVWLPDHMVSFWPDSIWAPEFTDLAT-------ASPSPHRHLDGLAVAAAVAVLTERAPL 82

Query: 96  GVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGL 155
              V D  RR+PA+ AQ A T+  L++GR ILG+G GE E   PYG ++++PV+RFEE L
Sbjct: 83  VSAVVDTVRRHPALLAQTALTLDHLSKGRFILGLGSGESENTVPYGFDFARPVSRFEEAL 142

Query: 156 ATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAW 215
             IR LWD++G  V  +  ++ L  A  D  PY G+ P IW+ A GPRML   GRYAD W
Sbjct: 143 RVIRLLWDTDGP-VDFDGEFYSLHQARLDTEPYHGRLPPIWIGASGPRMLDIAGRYADGW 201

Query: 216 VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKM 275
            P     P  Y++ L AVR +A  AGRDPM+ITP  ++  + G   D + E L + +VK 
Sbjct: 202 WPAGAWTPEHYAQMLGAVRVSAERAGRDPMAITPCFIQVCLIGEDDDALAEILRAPLVKA 261

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTP 335
             L + A+     G EHPMG  + G QD+ P  + R+ ++ +  +V P ++  VV  GTP
Sbjct: 262 FLLQVSAKTLGEFGFEHPMGDGWRGFQDIDPAALGRDRIVEFLHRVRPEMVLAVVPHGTP 321

Query: 336 DEVIDQVAEWRDHGLR 351
            +V   V  + D GLR
Sbjct: 322 KQVAKIVKSYVDAGLR 337


>tr|A0Q8X8|A0Q8X8_MYCA1 Tax_Id=243243 SubName: Full=Putative
           uncharacterized protein;[Mycobacterium avium]
          Length = 375

 Score =  213 bits (543), Expect = 2e-53
 Identities = 124/316 (39%), Positives = 170/316 (53%), Gaps = 12/316 (3%)

Query: 40  SYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLA----AGNRINRLRL 95
           S W+ DH+ +  P S+  PEF  L         A+  P   L  LA    A     R+ L
Sbjct: 30  SVWLPDHMVSFWPDSIWAPEFTDLAT-------ASASPHRHLDGLAVAAAAAVLTERVPL 82

Query: 96  GVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGL 155
              V D  RR+PA+ AQ A T+  L++GR ILG+G GE E   PYG ++++PV+RFEE L
Sbjct: 83  VSAVVDTVRRHPALLAQTALTLDHLSKGRFILGLGSGESENTVPYGFDFARPVSRFEEAL 142

Query: 156 ATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAW 215
             IR LWD++G  V     ++ L  A  D  PY  + P IW+ A GPRML   GRYAD W
Sbjct: 143 RVIRLLWDTDGP-VDFNGEFYSLHQARLDTEPYHDRLPPIWIGASGPRMLDIAGRYADGW 201

Query: 216 VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKM 275
            P     P  Y+  L AVR +A  AGRDPM+ITP  ++  + G   D + E L + +VK 
Sbjct: 202 WPAGAWTPEHYAEMLGAVRVSAERAGRDPMAITPCFIQVCLIGEDDDALAEILRAPLVKA 261

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTP 335
             L + A+     G EHPMG  + G QD+ P  + R+ ++ +  +V P ++  VV  GTP
Sbjct: 262 FLLQVSAKTLGEFGFEHPMGDGWRGFQDIDPAALGRDRIVEFLHRVRPEMVLAVVPHGTP 321

Query: 336 DEVIDQVAEWRDHGLR 351
            +V   V  + D GLR
Sbjct: 322 KQVAKIVKSYVDAGLR 337


>tr|B9L253|B9L253_THERP Tax_Id=309801 SubName:
           Full=N5,N10-methylenetetrahydromethanopterin
           reductase-related protein;[Thermomicrobium roseum]
          Length = 379

 Score =  213 bits (542), Expect = 3e-53
 Identities = 127/346 (36%), Positives = 186/346 (53%), Gaps = 5/346 (1%)

Query: 21  PPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTM 80
           PP       +    ++  D+  + DHL   VPR + +P    + ARL       Y+  ++
Sbjct: 16  PPLASVLGLVRLARLLRFDAVMVWDHLQDFVPRVLWSPRTTWI-ARLRRSPHPYYDFASL 74

Query: 81  LGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPY 140
           LG L+A     RLRLGV VTD  RR+P + AQ A T+  LTR   I+GIG GE E  EPY
Sbjct: 75  LGRLSA--HAGRLRLGVGVTDPIRRHPVLLAQTALTLAHLTRRPPIIGIGAGEAENLEPY 132

Query: 141 GVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAH 200
           G  + +PV R EE LA +RA  D+ G  +     ++ + + +F+L     + PEIW+ AH
Sbjct: 133 GFPFDRPVTRLEEALAILRACLDTPGT-IRFAGRFYQITDGVFELTAPPRRRPEIWLGAH 191

Query: 201 GPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWS 260
           GPRML  TGR+AD W P  I  P  Y+  L  VR AA  AGRDP  I P+    V+   +
Sbjct: 192 GPRMLELTGRFADGWYPNWIDSPERYAARLAQVRQAAERAGRDPTQIVPALQAPVLLAPT 251

Query: 261 RDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAK 320
            +     L    +++  L  PA+ W   G+EHP+G  F G  D IP+ +D   + +    
Sbjct: 252 ENAARRLLHHPALRLTGLLRPADEWRELGLEHPLGEHFRGYLDFIPERVDPHALRAALRA 311

Query: 321 VPPGLIREVVASGTPDEVIDQVAEWRDHGLRYL-LVINGSLVNPSL 365
           VPP L+      GTP++V+ ++ ++R+ GLR+L L+   +L +P +
Sbjct: 312 VPPELVERSFLWGTPEQVLARIRDYREAGLRFLGLLPVSALASPQV 357


>tr|Q1BAS7|Q1BAS7_MYCSS Tax_Id=164756 SubName: Full=Luciferase-like
           protein;[Mycobacterium sp.]
          Length = 391

 Score =  209 bits (531), Expect = 6e-52
 Identities = 125/316 (39%), Positives = 170/316 (53%), Gaps = 12/316 (3%)

Query: 40  SYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLR----L 95
           S W+ DH+ +  P S+ TPEF  L        D +  P   L  +A       L     L
Sbjct: 46  SIWLPDHMVSFWPDSIWTPEFTDLA-------DTSPSPHRHLDGMAVAAAAAVLTESTPL 98

Query: 96  GVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGL 155
              V D  RR+PA  AQ+A T+  L+ GR ILG+G GE E   PYG ++ +PV+RFEE L
Sbjct: 99  ATAVVDTVRRHPASLAQSALTIDHLSGGRFILGLGSGEAENIVPYGFDFDRPVSRFEEAL 158

Query: 156 ATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAW 215
             IR LWDS+G  V     +  LR A  D  P+ G+ P IW+ A GPRML   GR+AD W
Sbjct: 159 HVIRLLWDSDGP-VDFTGRFHRLRGARLDTEPFGGRVPPIWIGASGPRMLDLVGRHADGW 217

Query: 216 VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKM 275
            P     P  Y+  L AVR++A  AGRDPM+ITP  ++  +       + E LD+ +VK 
Sbjct: 218 WPAGAWTPQHYADMLGAVRSSAERAGRDPMAITPCFIQVCLIAKDDAALAEILDAPLVKA 277

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTP 335
             L + A+     G EHPMG D+ G  D+ P T+ RE ++ + A+V P  I  V+  GTP
Sbjct: 278 FLLQVSAQTLRAFGHEHPMGDDWRGFHDIDPATLTRERIVDFLARVRPEAILAVLPHGTP 337

Query: 336 DEVIDQVAEWRDHGLR 351
            +V   V ++ + GLR
Sbjct: 338 AQVARTVKDYVEAGLR 353


>tr|A3PXN9|A3PXN9_MYCSJ Tax_Id=164757 SubName: Full=Luciferase
           family protein;[Mycobacterium sp.]
          Length = 391

 Score =  209 bits (531), Expect = 6e-52
 Identities = 125/316 (39%), Positives = 170/316 (53%), Gaps = 12/316 (3%)

Query: 40  SYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLR----L 95
           S W+ DH+ +  P S+ TPEF  L        D +  P   L  +A       L     L
Sbjct: 46  SIWLPDHMVSFWPDSIWTPEFTDLA-------DTSPSPHRHLDGMAVAAAAAVLTESTPL 98

Query: 96  GVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGL 155
              V D  RR+PA  AQ+A T+  L+ GR ILG+G GE E   PYG ++ +PV+RFEE L
Sbjct: 99  ATAVVDTVRRHPASLAQSALTIDHLSGGRFILGLGSGEAENIVPYGFDFDRPVSRFEEAL 158

Query: 156 ATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAW 215
             IR LWDS+G  V     +  LR A  D  P+ G+ P IW+ A GPRML   GR+AD W
Sbjct: 159 HVIRLLWDSDGP-VDFTGRFHRLRGARLDTEPFGGRVPPIWIGASGPRMLDIVGRHADGW 217

Query: 216 VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKM 275
            P     P  Y+  L AVR++A  AGRDPM+ITP  ++  +       + E LD+ +VK 
Sbjct: 218 WPAGAWTPQHYADMLGAVRSSAERAGRDPMAITPCFIQVCLIAKDDAALAEILDAPLVKA 277

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTP 335
             L + A+     G EHPMG D+ G  D+ P T+ RE ++ + A+V P  I  V+  GTP
Sbjct: 278 FLLQVSAQTLRAFGHEHPMGDDWRGFHDIDPATLTRERIVDFLARVRPEAILAVLPHGTP 337

Query: 336 DEVIDQVAEWRDHGLR 351
            +V   V ++ + GLR
Sbjct: 338 AQVARTVKDYVEAGLR 353


>tr|A1UE85|A1UE85_MYCSK Tax_Id=189918 SubName: Full=Luciferase
           family protein;[Mycobacterium sp.]
          Length = 391

 Score =  209 bits (531), Expect = 6e-52
 Identities = 125/316 (39%), Positives = 170/316 (53%), Gaps = 12/316 (3%)

Query: 40  SYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLR----L 95
           S W+ DH+ +  P S+ TPEF  L        D +  P   L  +A       L     L
Sbjct: 46  SIWLPDHMVSFWPDSIWTPEFTDLA-------DTSPSPHRHLDGMAVAAAAAVLTESTPL 98

Query: 96  GVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGL 155
              V D  RR+PA  AQ+A T+  L+ GR ILG+G GE E   PYG ++ +PV+RFEE L
Sbjct: 99  ATAVVDTVRRHPASLAQSALTIDHLSGGRFILGLGSGEAENIVPYGFDFDRPVSRFEEAL 158

Query: 156 ATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAW 215
             IR LWDS+G  V     +  LR A  D  P+ G+ P IW+ A GPRML   GR+AD W
Sbjct: 159 HVIRLLWDSDGP-VDFTGRFHRLRGARLDTEPFGGRVPPIWIGASGPRMLDLVGRHADGW 217

Query: 216 VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKM 275
            P     P  Y+  L AVR++A  AGRDPM+ITP  ++  +       + E LD+ +VK 
Sbjct: 218 WPAGAWTPQHYADMLGAVRSSAERAGRDPMAITPCFIQVCLIAKDDAALAEILDAPLVKA 277

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTP 335
             L + A+     G EHPMG D+ G  D+ P T+ RE ++ + A+V P  I  V+  GTP
Sbjct: 278 FLLQVSAQTLRAFGHEHPMGDDWRGFHDIDPATLTRERIVDFLARVRPEAILAVLPHGTP 337

Query: 336 DEVIDQVAEWRDHGLR 351
            +V   V ++ + GLR
Sbjct: 338 AQVARTVKDYVEAGLR 353


>tr|A4TDK2|A4TDK2_MYCGI Tax_Id=350054 SubName: Full=Luciferase
           family protein;[Mycobacterium gilvum]
          Length = 371

 Score =  208 bits (529), Expect = 1e-51
 Identities = 126/320 (39%), Positives = 175/320 (54%), Gaps = 5/320 (1%)

Query: 40  SYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCV 99
           S W+ DHL +  P S+ TPEF  L A + P      +   + G +AA  R  R RL   V
Sbjct: 30  SLWMPDHLVSFWPDSIWTPEFTDL-AEVSPSPHRYLDTIALAGAVAA--RTTRTRLATSV 86

Query: 100 TDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLATIR 159
            D  RR+P + AQ+A T+  L+ GR ILG+G GERE   PYG +    V+RF E L  IR
Sbjct: 87  LDTVRRHPVMLAQSALTLSHLSDGRFILGLGAGERENLAPYGFDPRGTVSRFAEALQLIR 146

Query: 160 ALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIV 219
            LW+++G  +     YF L +A  D   ++   P IW+ A+GPRML   G Y D W P  
Sbjct: 147 LLWNADGP-IDFTGRYFTLEHARLDTEVHRSGPPPIWIGANGPRMLHLVGEYGDGWWPTG 205

Query: 220 IIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALG 279
              P  Y+R L  +R AA  AGRDP +ITP+ +   + G   D++ E L   +VK   L 
Sbjct: 206 SAGPETYARQLTRIREAAERAGRDPQAITPAKMVVCLIG-EPDELREILQRPLVKSLVLQ 264

Query: 280 MPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVI 339
           + A+A A  G  HPMG  + G+QD+ P+ + R+ +L    +V P  I  VV  GTP +V 
Sbjct: 265 LTADALADTGHRHPMGQRWRGIQDIDPRVLTRDRLLRLFEQVDPAAILSVVPHGTPTQVA 324

Query: 340 DQVAEWRDHGLRYLLVINGS 359
            QVAE+ + G R + V++ S
Sbjct: 325 AQVAEFGEAGARVVSVLDYS 344


>tr|O30260|O30260_ARCFU Tax_Id=2234 SubName: Full=Putative
           uncharacterized protein;[Archaeoglobus fulgidus]
          Length = 363

 Score =  177 bits (450), Expect = 2e-42
 Identities = 102/322 (31%), Positives = 171/322 (53%), Gaps = 10/322 (3%)

Query: 37  GADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLG 96
           G D+ W+ DHL    P  +         A   P     Y+ +  +   A      +++ G
Sbjct: 27  GYDAIWVADHLMGWYPHDLWKETIF---AMRYPSCHMFYDAFCEICYAAPATE--KIKFG 81

Query: 97  VCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLA 156
             VT+V RR+PAV  Q A T +  T+GR ILG+G GE E   PYG+++SKPVAR EE + 
Sbjct: 82  TSVTEVFRRHPAVLLQQAVTANHATKGRFILGLGAGEAENIVPYGIDFSKPVARLEEAVE 141

Query: 157 TIRALWDSN-GALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAW 215
            ++ + +S+ G  +  E  ++ L +A+FD+ P        W  AHG RML+ T ++ D W
Sbjct: 142 VMKLMLNSDYGEPINYEGKFYRLEDAVFDIKPISE--IPFWFGAHGNRMLKLTAKHGDGW 199

Query: 216 VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKM 275
           +P   + P  Y    E + + A + GR+P  IT +    ++     ++V++ L S I+K+
Sbjct: 200 LP-TTLPPEVYRERAEKLDSFAKEFGREPEEITKAIFVSLIVDEKPEEVEKLLKSPILKV 258

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTP 335
           +AL MP+E +   G +HP G  F G+ D IP    +E ++    +VP  ++R    +GTP
Sbjct: 259 HALLMPSEFYEMLGYKHPFG-KFYGLLDYIPTKYTKEQIMEAIKQVPDEIMRIAYIAGTP 317

Query: 336 DEVIDQVAEWRDHGLRYLLVIN 357
           +E++ Q  ++   G+ ++++ N
Sbjct: 318 EEIVQQFEQYEKLGVSHIVIWN 339


>tr|C8S627|C8S627_FERPL Tax_Id=589924 SubName: Full=Luciferase-like
           monooxygenase;[Ferroglobus placidus DSM 10642]
          Length = 354

 Score =  121 bits (304), Expect = 1e-25
 Identities = 102/321 (31%), Positives = 150/321 (46%), Gaps = 27/321 (8%)

Query: 36  MGADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRL 95
           +G DSYW+ DHL       VAT          V + DA  E W  LG LA      ++ +
Sbjct: 32  LGFDSYWMPDHL-------VATG---------VKRWDA-IEAWGALGALAV--LTEKIMI 72

Query: 96  GVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGL 155
              V+D  R +PAV AQ A T+ +++ GRAILGIG+GE     P+G+E+ KPV R  E L
Sbjct: 73  ATGVSDTYRVHPAVLAQKATTIDIISNGRAILGIGIGEAMNLVPFGIEYDKPVGRTIEAL 132

Query: 156 ATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAW 215
             IR L   N   V  E  Y+ L+ A     P +     I+VA   PR +R  G+Y D W
Sbjct: 133 EVIRRL--LNEDFVDFEGKYYKLKQAFIAPKPVQKPHYPIYVAGASPRTIRMAGKYGDGW 190

Query: 216 VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKM 275
           +P   +    Y    E V  AA + G+DP  I  +     V   ++D+  E +  +  K+
Sbjct: 191 LP-ANLTVEKYKEGRETVMKAAKEVGKDPEKIDMAHFMYGVIAKTKDEARERV-MLPAKL 248

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLI-REVVASGT 334
             L  P    A  G E P   DF     L+    D +  L    K+P  ++ +  +  GT
Sbjct: 249 LLLTRPRILEA-IGYEPPT-YDFEMTFKLV-FPRDAQRWLEEAKKLPDEVVEKSPIVYGT 305

Query: 335 PDEVIDQVAEWRDHGLRYLLV 355
            D+ I++  ++   G R+ ++
Sbjct: 306 VDDFIERFEQYYKVGCRHFVM 326


>tr|B3T418|B3T418_9ARCH Tax_Id=455572 SubName: Full=Putative
           Luciferase-like monooxygenase;[uncultured marine
           crenarchaeote HF4000_ANIW133K13]
          Length = 361

 Score =  119 bits (297), Expect = 8e-25
 Identities = 86/308 (27%), Positives = 145/308 (47%), Gaps = 11/308 (3%)

Query: 76  EPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGERE 135
           +PW ML  +AA    N + LG CVTD  RR+P+  A AA T+  +++GRAILGIG GE +
Sbjct: 55  DPWVMLSAIAAVT--NHVELGTCVTDAIRRHPSNIALAAITLDRVSKGRAILGIGAGEAQ 112

Query: 136 GNEPYGVEWSKPVARFEEGLATIRALWDSN-GALVTRESPYFPLRNALFDLPPYKGKWPE 194
             + + + + KPV+++EE +  I+ L+ S     V  E  Y+ L +A    PP +   P 
Sbjct: 113 NLKEFCIPFEKPVSKWEEQIQVIKKLYGSTPDNTVDFEGKYYKLESACLQAPPIRKPHPP 172

Query: 195 IWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRG 254
           I++A+ G R L  TG+Y D W+PI    P  +    + +  + ++  R         +  
Sbjct: 173 IYMASGGKRTLSLTGKYGDGWLPIG-YTPELFKDHKKQIEVSMNENNRTQEEKDNFQMAL 231

Query: 255 VVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRE-- 312
            +  +  DD +E+   +   +       E    H ++   G DF  V+     +M  +  
Sbjct: 232 DIDVYFSDDAEESWAKMKEAVKVSLFKPEVLRVHQLKDIEGFDF--VKYFTEYSMSNQDW 289

Query: 313 --TVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLV-INGSLVNPSLRKTV 369
              +     K+P  + R     GTPD++I     +   G+ + ++   G     S+ K  
Sbjct: 290 IIKMREAATKIPDAVARSSTGVGTPDDIIPIFERFVKAGVNHFVIRFWGKNYFGSIDKFA 349

Query: 370 TAVLPHAK 377
           T V+P+ K
Sbjct: 350 THVIPYFK 357


>tr|A9A4M7|A9A4M7_NITMS Tax_Id=436308 SubName: Full=Luciferase
           family protein;[Nitrosopumilus maritimus]
          Length = 368

 Score =  116 bits (291), Expect = 4e-24
 Identities = 90/303 (29%), Positives = 137/303 (45%), Gaps = 46/303 (15%)

Query: 76  EPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGERE 135
           +PW ML  +AA    N + LG CVTD  RR+P+  A AA T+  +++GRAILGIG GE +
Sbjct: 61  DPWVMLSAIAAVT--NNVELGTCVTDAIRRHPSNIALAAITLDRVSKGRAILGIGAGEAQ 118

Query: 136 GNEPYGVEWSKPVARFEEGLATIRALWDSN-GALVTRESPYFPLRNALFDLPPYKGKWPE 194
             + + + + KPV+++EE + TI  L+ S     V  E  Y+ L  A    PP +   P 
Sbjct: 119 NLKEFCIPFEKPVSKWEEQIETIHTLYKSTPDNTVDYEGKYYKLEGACLQAPPIRKPHPP 178

Query: 195 IWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRG 254
            ++A+ G R L  TG+  D W+PI       Y+  L    AA      D  + T      
Sbjct: 179 TYMASGGKRTLALTGKLGDGWLPI------GYTPELFEDHAAQIKKSMDENNRTQE---- 228

Query: 255 VVTGWSRDDVDEALD-SVIVKMNALGMPAEAWAR-----------------HGVEHPMGA 296
                 +D+   ALD  V    +A     E+WAR                 H ++   G 
Sbjct: 229 -----EKDNFQYALDIDVYFSEDA----EESWARMKEAVKVSLFKPEVLRVHNLKEIEGF 279

Query: 297 DFTGVQDLIPQTMDRE----TVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRY 352
           DF  V+     +M  +     +     K+P  + R   A GTPD++I     + D G+ +
Sbjct: 280 DF--VKYFTEYSMSNQEWIVKMREAATKIPEAVARSSTAVGTPDDIIPTFERFMDAGVNH 337

Query: 353 LLV 355
            ++
Sbjct: 338 FVI 340


>tr|B3T8P7|B3T8P7_9ARCH Tax_Id=455593 SubName: Full=Putative
           Luciferase-like monooxygenase;[uncultured marine
           crenarchaeote HF4000_APKG5N21]
          Length = 361

 Score =  115 bits (288), Expect = 9e-24
 Identities = 83/308 (26%), Positives = 149/308 (48%), Gaps = 11/308 (3%)

Query: 76  EPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGERE 135
           +PW ML ++AA    N + LG CVTD  RR+P+  A AA T+  +++GRAILGIG GE +
Sbjct: 55  DPWVMLSSIAAVT--NHVELGTCVTDAIRRHPSNIALAAITLDRVSKGRAILGIGAGEAQ 112

Query: 136 GNEPYGVEWSKPVARFEEGLATIRALWDSN-GALVTRESPYFPLRNALFDLPPYKGKWPE 194
             + + + + KPV+++EE +  I+ L+ S+    V  E  Y+ L +A       +   P 
Sbjct: 113 NLKEFCIPFDKPVSKWEEQIQVIKKLYGSSPDNTVDFEGKYYKLESACLQASSIRKPHPP 172

Query: 195 IWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRG 254
           I++A+ G R L+ TG+Y D W+PI    P  +    + + A+ ++  R         +  
Sbjct: 173 IYMASGGKRTLKLTGKYGDGWLPIG-YTPELFEDHKKQIEASMNENNRTQEEKDNFQMAL 231

Query: 255 VVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRET- 313
            +  +  DD +E+   +   +       E    H ++   G DF  V+     +M  ++ 
Sbjct: 232 DIDVYFSDDAEESWARMKEAVKVSLFKPEILRVHELKDIEGFDF--VKYFTEYSMSNQSW 289

Query: 314 ---VLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLV-INGSLVNPSLRKTV 369
              +     K+P  + R     GTPD++I    ++   G+ + ++   G     S+ +  
Sbjct: 290 IVKMREAATKIPDAIARSSTGVGTPDDIIPIFEKFIKAGVNHFVIRFWGKNYFGSIDRFA 349

Query: 370 TAVLPHAK 377
           + V+P+ K
Sbjct: 350 SQVIPYFK 357


>tr|B3TCN1|B3TCN1_9ARCH Tax_Id=455613 SubName: Full=Putative
           Luciferase-like monooxygenase;[uncultured marine
           crenarchaeote HF4000_APKG10L15]
          Length = 361

 Score =  114 bits (286), Expect = 2e-23
 Identities = 83/308 (26%), Positives = 147/308 (47%), Gaps = 11/308 (3%)

Query: 76  EPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGERE 135
           +PW ML ++AA    N + LG CVTD  RR+P+  A AA T+  +++GRAILGIG GE +
Sbjct: 55  DPWVMLSSIAAVT--NHVELGTCVTDAIRRHPSNIALAAITLDRVSKGRAILGIGAGEAQ 112

Query: 136 GNEPYGVEWSKPVARFEEGLATIRALWDSN-GALVTRESPYFPLRNALFDLPPYKGKWPE 194
             + + + + KPV+++EE +  I+ L+ S+    V  E  Y+ L +A       +   P 
Sbjct: 113 NLKEFCIPFDKPVSKWEEQIQVIKKLYSSSPDNTVDFEGKYYKLESACLQASSIRKPHPP 172

Query: 195 IWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRG 254
            ++A+ G R L+ TG+Y D W+PI    P  +    + + A+ ++  R         +  
Sbjct: 173 TYMASGGKRTLKLTGKYGDGWLPIG-YTPELFEDHKKQIEASMNENNRTQEEKDNFQMAL 231

Query: 255 VVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRET- 313
            +  +  DD +E+   +   +       E    H ++   G DF  V+     +M  ++ 
Sbjct: 232 DIDVYFSDDAEESWARMKEAVKVSLFKPEILRVHELKDIEGFDF--VKYFTEYSMSNQSW 289

Query: 314 ---VLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLV-INGSLVNPSLRKTV 369
              +     K+P  + R     GTPD++I     +   G+ + ++   G     S+ K  
Sbjct: 290 IVKMREAATKIPDAIARSSTGVGTPDDIIPIFERFIKAGVNHFVIRFWGKNYFGSIDKFA 349

Query: 370 TAVLPHAK 377
           + V+P+ K
Sbjct: 350 SQVIPYFK 357


>tr|A0RV14|A0RV14_CENSY Tax_Id=46770 SubName: Full=Flavin-dependent
           oxidoreductase;[Cenarchaeum symbiosum]
          Length = 390

 Score =  114 bits (284), Expect = 3e-23
 Identities = 84/308 (27%), Positives = 143/308 (46%), Gaps = 11/308 (3%)

Query: 76  EPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGERE 135
           +PW ML  +AA    N + +G CVTD  RR+P+  A AA T+  +++GRAILGIG GE +
Sbjct: 85  DPWVMLSAIAAIT--NNVEIGTCVTDAIRRHPSNIALAAITLDRVSKGRAILGIGAGEAQ 142

Query: 136 GNEPYGVEWSKPVARFEEGLATIRALWDSN-GALVTRESPYFPLRNALFDLPPYKGKWPE 194
             + + + + KPV+++EE +  I+AL+ S+    V     Y+ L+ A    PP +   P 
Sbjct: 143 NLKEFCIPFEKPVSKWEEQIEVIKALYSSSPDNTVDYSGKYYDLKGACLQAPPIRKPHPP 202

Query: 195 IWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRG 254
            ++A+ G R L  TG+  D W+PI    P  +      +  +     R         +  
Sbjct: 203 TYMASGGKRTLMLTGKLGDGWLPIG-YTPELFEDHRGQIVDSMKKHDRTEEEKENFQMAL 261

Query: 255 VVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRE-- 312
            +  +  +D +E+   +   +       E    H ++   G DF  V+     +M  +  
Sbjct: 262 DIDVYFSEDAEESWARMKEAVKVSLFKPEVLRVHNLKEIEGFDF--VKYFTEYSMSNQEW 319

Query: 313 --TVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLV-INGSLVNPSLRKTV 369
              +     ++P G+ R   A GTPD+VI     +   G+ + ++   G     S+ K  
Sbjct: 320 IVKMREAATRIPDGVARSSTAIGTPDDVIPTFERFLKAGVNHFVIRFWGKDYFGSIDKFA 379

Query: 370 TAVLPHAK 377
           T V+PH +
Sbjct: 380 THVMPHLR 387


>tr|C8SAR7|C8SAR7_FERPL Tax_Id=589924 SubName: Full=Luciferase-like
           monooxygenase;[Ferroglobus placidus DSM 10642]
          Length = 332

 Score =  110 bits (275), Expect = 3e-22
 Identities = 85/299 (28%), Positives = 137/299 (45%), Gaps = 14/299 (4%)

Query: 74  NYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGE 133
           N   + ML  LA   + ++++LG  VT+    +PA+TA A AT++ L+ GRA+LGIG G+
Sbjct: 39  NRNVYAMLAILAL--KTSKIKLGPGVTNPYHISPALTASAIATINELSEGRAVLGIGAGD 96

Query: 134 REGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWP 193
           +   E  G+ W KP+ R  E +  IRAL   +G  V  +   F +  A  D   +K    
Sbjct: 97  KVTFERIGITWEKPLKRMREAVEIIRAL--HSGKPVNYDGEIFKMNGAKLD---FKAGNI 151

Query: 194 EIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVR 253
            I++ A GP+ML+      D  V I    P D+  A E + A  S AG+        A  
Sbjct: 152 PIYIGAQGPKMLQLAAELGDG-VLINASHPRDFEAAKENIEAGLSKAGKSKEEFDVVAYA 210

Query: 254 GVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRET 313
            +     R+    A   ++V     G P   + RHG+      D   V++ +     +  
Sbjct: 211 SMSVDKDREKARNAA-RIVVAFIVAGSPEVIFERHGISMD---DVNKVREALNNAFTKGD 266

Query: 314 VLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
                  V   +I     SGTP++VI+++ E    G+    V+ GS + P  +K++  +
Sbjct: 267 WAGVGKAVTDEMIDCFSISGTPEDVIERIKELSKAGVTQ--VVAGSPIGPDKKKSIQLI 323


>tr|C8SBQ9|C8SBQ9_FERPL Tax_Id=589924 SubName: Full=Luciferase-like
           monooxygenase;[Ferroglobus placidus DSM 10642]
          Length = 338

 Score =  108 bits (269), Expect = 1e-21
 Identities = 90/309 (29%), Positives = 152/309 (49%), Gaps = 34/309 (11%)

Query: 54  SVATPEFL-GLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQ 112
           S+ TP+ L G+G     K    YE +++LG LA   R     LGVCV+DV RRNPAV AQ
Sbjct: 30  SIFTPDHLVGIGL----KNFYAYEAFSILGYLAGKTRAT---LGVCVSDVLRRNPAVVAQ 82

Query: 113 AAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRE 172
           AA+T+  ++    ILG+G GE     P+G+E    V++ EEG+  IR L   +G +V+ E
Sbjct: 83  AASTIASMSGREFILGLGAGEGMNLLPFGIETKFLVSKLEEGVKIIREL--LSGRVVSYE 140

Query: 173 SPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEA 232
             +F +++A   +PP +    +IWVA + P+ +  T +YAD W+P   +    Y   L+ 
Sbjct: 141 GKFFRMKDAF--VPPSEN--VKIWVAGNSPKTMEITAKYADGWIPTATMGEKRYEENLKK 196

Query: 233 VRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMP--AEAWARHGV 290
           +        R    +        V   S D+  E ++ +  K  AL  P   E   + G+
Sbjct: 197 I-------VRKHRKVEAGLFAYTVVAKSYDEAREMIE-IPGKFIALLSPFRGEFLKKVGI 248

Query: 291 EH----PMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWR 346
           +     P    FT  ++ +      E +L    ++P  L+      G+P++V +++ ++ 
Sbjct: 249 DEKDLPPNILHFTFTKENV------EKLLEVAKQIPFELVERRYFYGSPEDVAERMEKFV 302

Query: 347 DHGLRYLLV 355
             G+ + ++
Sbjct: 303 KAGVEHFVL 311


>tr|A0B5M9|A0B5M9_METTP Tax_Id=349307 SubName:
           Full=Methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11;[Methanosaeta thermophila]
          Length = 318

 Score =  106 bits (265), Expect = 4e-21
 Identities = 88/287 (30%), Positives = 134/287 (46%), Gaps = 31/287 (10%)

Query: 91  NRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVAR 150
           NR+RLG  VT+   R+P +TA + A+++ L+ GRAILGIG G++   +  G+ W KP+ R
Sbjct: 53  NRIRLGTGVTNPYTRSPIITASSIASINELSGGRAILGIGPGDKATFDAMGIAWEKPLTR 112

Query: 151 FEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGR 210
             E ++ IRAL       VT+      L  +  ++P Y G        A GP+ML   G 
Sbjct: 113 VRESVSVIRALLRKE--RVTQGGMNAQLSFSAGNIPIYMG--------AQGPKMLELAGE 162

Query: 211 YADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRD-DVDEALD 269
            AD  V I    P D+  A+  +R     AGRDP  +   A     T +S D D  +A  
Sbjct: 163 IADG-VLINASHPEDFRAAIPLIRNGVQRAGRDPEDVKVCA----YTSFSVDRDRSKAAS 217

Query: 270 SV--IVKMNALGMPAEAWARHGVEHPMGADFTGVQ--DLIPQTMDRETVLSYTAKVPPGL 325
               +V   A G P     RHG+         GVQ  D I + + +    S  + V   +
Sbjct: 218 EARKVVAFIAAGSPDAVLERHGI---------GVQERDAISKAISKGDFASAMSSVTDKM 268

Query: 326 IREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
           +     +GTPD+   +V E    G+  ++V  GS + P   +++  +
Sbjct: 269 LDVFSVTGTPDDCRARVDELLATGVNQIVV--GSPIGPDKERSIRLI 313


>tr|O29071|O29071_ARCFU Tax_Id=2234 SubName:
           Full=N5,N10-methylenetetrahydromethanopterin reductase
           (Mer-2);[Archaeoglobus fulgidus]
          Length = 348

 Score =  103 bits (258), Expect = 3e-20
 Identities = 84/273 (30%), Positives = 132/273 (48%), Gaps = 13/273 (4%)

Query: 89  RINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPV 148
           + ++  LG  VTDV R +P+V AQ  AT+  L+ GRA LG+G GE    +P+G+EW KP 
Sbjct: 61  KTSKAMLGTGVTDVVRYHPSVLAQIMATIDHLSYGRAFLGLGAGEAMNIKPFGIEWKKPY 120

Query: 149 ARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRAT 208
               EG+  I+ LW   G   + E   F L +A   + P + K P I++ A+G +     
Sbjct: 121 TTLREGIEIIKRLW--AGDRFSYEGKRFRLDDAFLQIKPLQ-KIP-IYLGANGVKTRELA 176

Query: 209 GRYADAWVPIVIIRPTDYSRALEAVRAAASDAGR--DPMSITPSAVRGVVTGWSRDDVDE 266
           G   D W+PI    P  Y   L+ V    S AGR  D +         V T + R  ++ 
Sbjct: 177 GEICDGWMPIA-ETPKTYRENLKDVERGCSKAGRNLDEIDTALQIYTAVDTSFER-AMER 234

Query: 267 ALDSVIVKMNALGMPAEAWARHGVEHPMGAD--FTGVQDLIPQTMDRETVLSYTAKVPPG 324
           A     V ++A     +  A + +E P G    F   Q L+   M  E V   ++ V   
Sbjct: 235 ARQFSGVIVSAAEKAEQ--AGYSLEMPEGISKKFYFEQLLLDDKMLMEFV-KLSSLVTEE 291

Query: 325 LIREVVASGTPDEVIDQVAEWRDHGLRYLLVIN 357
           +IR+    GTP++  +++ E+   G+++ ++IN
Sbjct: 292 MIRDFFIVGTPEDCEEKIEEFVKAGVKHFMLIN 324


>tr|C7P5G0|C7P5G0_METFA Tax_Id=573064 SubName:
           Full=5,10-methylenetetrahydromethanopterin
           reductase;[Methanocaldococcus fervens]
          Length = 331

 Score =  103 bits (258), Expect = 3e-20
 Identities = 79/282 (28%), Positives = 130/282 (46%), Gaps = 14/282 (4%)

Query: 91  NRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVAR 150
           N+++LG  VT+   R+PA+TA A AT+  L+ GRA+LGIG G++   +  G+EW KPV  
Sbjct: 54  NKIKLGPGVTNPYVRSPAITASAIATLDELSGGRAVLGIGPGDKATFDSLGIEWVKPVTT 113

Query: 151 FEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGR 210
            +E +  IR L    G  V+       L  A   + P + K P +++ A GP+ML   G 
Sbjct: 114 LKESIEVIRKL--LAGERVSFNGNVVKLAGAALAVKPIQKKVP-VYMGAQGPKMLETAGM 170

Query: 211 YADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDS 270
            AD  V I    P D+  A+  ++  A  AGR    I  +A   +      D   +A   
Sbjct: 171 IADG-VLINASNPKDFEAAIPLIKKGAEAAGRSMDEIDVAAYACMSVDKKADKAKQAAVP 229

Query: 271 VIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVV 330
           V+  + A G P     RHG++           + I + + +    +    V   ++    
Sbjct: 230 VVAFI-AAGSPPVVLERHGID-------VEKVEKIREALKKGDFGTAFGAVDDDMLEAFS 281

Query: 331 ASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
             GTPD+V+++  E    G+    ++ GS + P+    +  +
Sbjct: 282 IYGTPDDVVEKCKELAKMGVTQ--IVAGSPIGPNKETAIKLI 321


>sp|O29196|MER_ARCFU Tax_Id=2234 (mer)RecName:
           Full=5,10-methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11; AltName: Full=Coenzyme F420-dependent
           N(5),N(10)-methylenetetrahydromethanopterin reductase;
           AltName: Full=Methylene-H(4)MPT reductase;[Archaeoglobus
           fulgidus]
          Length = 332

 Score =  103 bits (256), Expect = 5e-20
 Identities = 91/336 (27%), Positives = 139/336 (41%), Gaps = 39/336 (11%)

Query: 37  GADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLG 96
           G D  WI DH N                         N   ++ML  LA   R   ++LG
Sbjct: 27  GFDYTWITDHYN-------------------------NRNVYSMLTILALKTRT--IKLG 59

Query: 97  VCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLA 156
             VT+    +PA+TA A  T++ ++ GRA+LGIG G++   E  G+ W KP+ R  E + 
Sbjct: 60  PGVTNPYHISPALTASAIGTINEISGGRAVLGIGAGDKVTFERIGITWEKPLKRMREAVE 119

Query: 157 TIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAWV 216
            IR L  + G  V  +   F    A     P  G  P I++ A GP+ML+      D  V
Sbjct: 120 IIRQL--TEGKAVKYDGEIFKFNGAKLGFKP--GSIP-IYIGAQGPKMLQLAAELGDG-V 173

Query: 217 PIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIVKMN 276
            I    P D+  A E + A  + AG+   +    A   +     RD    A   ++V   
Sbjct: 174 LINASHPKDFEVAKENIDAGLAKAGKSRDAFDTVAYASMSVDKDRDKARNAA-RIVVAFI 232

Query: 277 ALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTPD 336
             G P     RHG+          V++ +     +         V   +I     SGTPD
Sbjct: 233 VAGSPPTVLERHGLSEDA---VNAVREALNNAFTKGDWGGVAKSVTDEMIDIFSISGTPD 289

Query: 337 EVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
           +VI+++ E    G+    V+ GS + P  +K++  +
Sbjct: 290 DVIERINELSKAGVTQ--VVAGSPIGPDKKKSIQLI 323


>tr|C9REM5|C9REM5_METVM Tax_Id=579137 SubName:
           Full=5,10-methylenetetrahydromethanopterin
           reductase;[Methanocaldococcus vulcanius]
          Length = 331

 Score =  102 bits (255), Expect = 6e-20
 Identities = 84/294 (28%), Positives = 135/294 (45%), Gaps = 16/294 (5%)

Query: 91  NRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVAR 150
           N+++LG  VT+   R+PA+TA A AT+  L+ GRA+LGIG G++   +  G+EW KPV  
Sbjct: 54  NKIKLGPGVTNPYVRSPAITASAIATLDELSGGRAVLGIGPGDKATFDALGIEWVKPVTT 113

Query: 151 FEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGR 210
            +E +  +R L    G  V+ E     +  A   + P + K P I++ A GP+ML   G 
Sbjct: 114 LKESIEVMRKL--LAGERVSFEGKVVKIAGASLAVKPIQEKVP-IYMGAQGPKMLETAGM 170

Query: 211 YADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDS 270
            AD  V I    P D+  A+  ++  A  AGR    I  +A   +      D   +A   
Sbjct: 171 IADG-VLINASNPKDFEVAIPLIKKGAEAAGRSMDEIDVAAYACMSVDKKADKAKQAAIP 229

Query: 271 VIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVV 330
           V+  + A G P     RHG++           + I   +           V   ++    
Sbjct: 230 VVAFI-AAGSPPVVLERHGIDMEK-------VEAIRNALKSGNFPEAFKNVDDKMLEAFS 281

Query: 331 ASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAVLPHAKVLRGLKK 384
             GTP+EV+++  +  + G+    ++ GS + P+  K     L   KV+  LK+
Sbjct: 282 IYGTPEEVVEKCKKLAEMGVTQ--IVAGSPIGPN--KETAIKLIGKKVIPALKE 331


>sp|Q58929|MER_METJA Tax_Id=2190 (mer)RecName:
           Full=5,10-methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11; AltName: Full=Coenzyme F420-dependent
           N(5),N(10)-methylenetetrahydromethanopterin reductase;
           AltName: Full=Methylene-H(4)MPT
           reductase;[Methanocaldococcus jannaschii]
          Length = 331

 Score =  102 bits (253), Expect = 1e-19
 Identities = 82/294 (27%), Positives = 135/294 (45%), Gaps = 16/294 (5%)

Query: 91  NRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVAR 150
           N+++LG  VT+   R+PA+TA A AT+  L+ GRA+LGIG G++   +  G+EW KPV  
Sbjct: 54  NKIKLGPGVTNPYVRSPAITASAIATLDELSGGRAVLGIGPGDKATFDALGIEWVKPVTT 113

Query: 151 FEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGR 210
            +E +  IR L    G  V+ E     +  A   + P +   P +++ A GP+ML   G 
Sbjct: 114 LKESIEVIRKL--LAGERVSYEGKVVKIAGAALAVKPIQKAVP-VYMGAQGPKMLETAGM 170

Query: 211 YADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDS 270
            AD  V I    P D+  A+  ++  A  AGR    I  +A   +    + D   +A   
Sbjct: 171 IADG-VLINASNPKDFEAAIPLIKKGAEAAGRSMDEIDVAAYACMSVDKNADKAKQAAVP 229

Query: 271 VIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVV 330
           V+  + A G P     RHG++           + I   +           V   ++    
Sbjct: 230 VVAFI-AAGSPPVVLERHGIDMEK-------VEAIRNALKSGNFPEAFKNVDDTMLEAFS 281

Query: 331 ASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAVLPHAKVLRGLKK 384
             GTP++V+++  +  + G+    ++ GS + P+  K     L   KV+  LK+
Sbjct: 282 IYGTPEDVVEKCKKLAEMGVTQ--IVAGSPIGPN--KETAIKLIGKKVIPALKE 331


>tr|B9L2E3|B9L2E3_THERP Tax_Id=309801 SubName: Full=Putative
           dehydrogenase;[Thermomicrobium roseum]
          Length = 311

 Score =  101 bits (251), Expect = 2e-19
 Identities = 83/280 (29%), Positives = 120/280 (42%), Gaps = 23/280 (8%)

Query: 17  HSRLPPSMIARSSMMAGAVMGADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYE 76
           + RLP      +       +G DS W+ DHL    P     PE +             +E
Sbjct: 24  NGRLPRWSDLEAMARLAEEIGLDSLWVVDHLLYRTPDG--EPEGI-------------WE 68

Query: 77  PWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREG 136
            W++L   AA  +  R+ LG  V     RNPA+ A+ A TV+ ++ GR ILG+G G  E 
Sbjct: 69  CWSLLSAFAAVTK--RITLGTLVLCTNWRNPALIAKMAETVNEISGGRLILGLGAGNTEQ 126

Query: 137 N-EPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEI 195
               +G  W + V+RF E LA +  L       +     ++ +R+ L      + + P I
Sbjct: 127 EFRRFGFPWERRVSRFAEALAIVHGL--LRNGWIDYAGEFYTVRDCLLRPRGPRSQGPPI 184

Query: 196 WVAAHGPRMLRATGRYADAW---VPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAV 252
            V  +GPR+LR   +YAD W         R +     +EA RAA  D GRD  S+T SA 
Sbjct: 185 LVGGNGPRVLRLAAQYADIWNTYYDFTGNRASGLGPQIEAFRAACRDVGRDWSSVTLSAS 244

Query: 253 RGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEH 292
             V             D V      +     A+AR G++H
Sbjct: 245 ALVAFPGHGRIYGVVADPVRGTPEEIAEEFRAYARAGIQH 284


>tr|Q12TK2|Q12TK2_METBU Tax_Id=259564 (mer)SubName: Full=Coenzyme
           F420-dependent
           N(5),N(10)-methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11;[Methanococcoides burtonii]
          Length = 328

 Score = 99.4 bits (246), Expect = 7e-19
 Identities = 85/339 (25%), Positives = 138/339 (40%), Gaps = 48/339 (14%)

Query: 37  GADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLG 96
           G D+ WI DH N                         N + ++ L  LA     N +++G
Sbjct: 27  GFDNVWITDHYN-------------------------NRDVYSTLAVLAMNT--NSIKIG 59

Query: 97  VCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLA 156
             VT+   RN A+TA +   ++ ++ GRAILG+G G++   +  G+EW KP+   +E ++
Sbjct: 60  TGVTNPYTRNAAITASSIGAINEISGGRAILGLGPGDKATFDAMGIEWEKPLTTTKENIS 119

Query: 157 TIRALWDSNGALVTRESPYFPLRNALF---DLPPYKGKWPEIWVAAHGPRMLRATGRYAD 213
            +R+ +      +  +   F      F   D+P Y G        A GP+ML   G  AD
Sbjct: 120 ALRSFFAGEKVTMDGDMVQFSGAKLAFKTGDVPIYMG--------AQGPKMLELAGEVAD 171

Query: 214 AWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDSVIV 273
             V I    P D+  A++ + + A  AGRDP  +  +A               A   V+V
Sbjct: 172 G-VLINASHPNDFEVAVKQITSGAKKAGRDPKDVDVAAYACFSIDKDAAKARSAA-KVVV 229

Query: 274 KMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASG 333
                G P     RHG++    AD  G           +        V   ++     SG
Sbjct: 230 AFIVAGSPDMVLERHGIDVAAKADIGGA------IAKGDFGALMGDMVTNNMMESFSISG 283

Query: 334 TPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
           TPD+   ++ E  D G+    ++ GS + P+  K +  +
Sbjct: 284 TPDDCKARINELLDIGVTQ--IVAGSPIGPNKEKAIKLI 320


>tr|A6UV10|A6UV10_META3 Tax_Id=419665 SubName:
           Full=5,10-methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11;[Methanococcus aeolicus]
          Length = 323

 Score = 99.4 bits (246), Expect = 7e-19
 Identities = 82/300 (27%), Positives = 135/300 (45%), Gaps = 35/300 (11%)

Query: 91  NRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVAR 150
           N++++G  VT+   R+PAVTA A  T+  ++ GRA+LGIG G++   +  G+EW+KPV+ 
Sbjct: 54  NKIKIGPGVTNPYVRSPAVTASAMITLDEVSTGRAVLGIGPGDKATFDALGIEWTKPVST 113

Query: 151 FEEGLATIRALWD-----SNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRML 205
            ++ +A ++AL D         L  + S   P                 I++ A GP+ML
Sbjct: 114 IKKAIADMKALMDGERLEEGAVLAIKPSTKIP-----------------IYMGAQGPKML 156

Query: 206 RATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVD 265
              G  +D  V I    P D+  A+  +R  A  AGR    +  +A   +    + D   
Sbjct: 157 ETAGMISDG-VLINASNPKDFEAAVPLIRKGAEAAGRSMDEVDVAAYACMSVDKNADKAK 215

Query: 266 EALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGL 325
            A  S +V   A G P     RHG++    A        I   + +    +    V   +
Sbjct: 216 GAA-SPVVAFIAAGSPPMVLERHGIDQEKVA-------TISAALKKGDFGTAFGTVDDTM 267

Query: 326 IREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAVLPHAKVLRGLKKL 385
           +      GTPDEV++++A     G+    ++ GS + P+  K  +  L   KV+  +K L
Sbjct: 268 LEAFSLYGTPDEVVEKIAALGKMGVTQ--IVAGSPIGPN--KDTSIKLIGKKVVPAVKDL 323


>tr|C5U4Q8|C5U4Q8_9EURY Tax_Id=573063 SubName: Full=Luciferase-like
           monooxygenase;[Methanocaldococcus infernus ME]
          Length = 331

 Score = 99.0 bits (245), Expect = 9e-19
 Identities = 76/282 (26%), Positives = 130/282 (46%), Gaps = 14/282 (4%)

Query: 91  NRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVAR 150
           N+++LG  VT+   RNPA+TA A AT+  L+ GRA+LGIG G++   +  G+EW KPV  
Sbjct: 54  NKIKLGPGVTNPYVRNPAITASAIATLDELSGGRAVLGIGPGDKATFDTLGIEWVKPVTT 113

Query: 151 FEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGR 210
            +E +  IR L    G  V+ +     L  A  ++ P     P +++ A GP+ML   G 
Sbjct: 114 LKETVEVIRKL--LAGERVSYDGKVVKLAGAALNVKPINKDVP-VYIGAQGPKMLETAGA 170

Query: 211 YADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEALDS 270
             D  V I    P D+  A+  ++  A  AG+    +  +A   +      +   +A   
Sbjct: 171 IGDG-VLINASNPKDFEAAIPLIKKGAESAGKKLEDVDIAAYACMSVDKKSEKAKQAAVP 229

Query: 271 VIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVV 330
           V+  + A G P     RH +      D   V+  I + + +    +    V   ++    
Sbjct: 230 VVAFIVA-GSPEVVLKRHNI------DMEKVEK-IREALKKGDFGTAFGTVDDAMLEAFS 281

Query: 331 ASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
             GTP+EV+++  +  + G+    ++ GS + P   K +  +
Sbjct: 282 IYGTPEEVVEKCKKLLEIGVTQ--IVAGSPIGPDKEKAIKLI 321


>tr|C1RNB6|C1RNB6_9CELL Tax_Id=446466 SubName:
           Full=FAD/FMN-dependent dehydrogenase;[Cellulomonas
           flavigena DSM 20109]
          Length = 754

 Score = 98.2 bits (243), Expect = 2e-18
 Identities = 93/280 (33%), Positives = 130/280 (46%), Gaps = 31/280 (11%)

Query: 64  GARLVPKVDANYEP-----WTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVH 118
           G  LV   D  Y+P     WT+L  +AA  R  R+ L   V +V  R PAV A+AAA++ 
Sbjct: 35  GLDLVTFQDHPYQPAFLDTWTLLSWVAA--RTERVHLAGNVLNVPLRPPAVLARAAASLD 92

Query: 119 LLTRGRAILGIGVGE-REGNEPYGVEWSKP---VARFEEGLATIRALWDSNGALVTRESP 174
           LL+ GR  LG+G G   +  E  GV    P   V   +E +A IRALWD++G    R   
Sbjct: 93  LLSGGRVELGLGAGGFWDAIEGMGVPRLTPGQAVDALDEAIAVIRALWDTDGRGPLRVGG 152

Query: 175 YFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAWVP-IVIIRPTDYSRALEAV 233
               R A     P       IWV A+ PRMLR  GR AD W+P +  ++P D +R    +
Sbjct: 153 EHH-RLAGAKRGPAPAHDIGIWVGAYKPRMLRLVGRTADGWLPSLSYLQPGDLARGNTTI 211

Query: 234 RAAASDAGRDPMSITPSA-VRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEH 292
             AA+ AGRDP  +     V G  +    D +D             G PA+ W    V +
Sbjct: 212 DEAATAAGRDPREVRRLLNVNGRFSPTPGDGLD-------------GPPAQ-WVDELVRY 257

Query: 293 PMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVAS 332
            +     G+   +  T D  T+ ++  +V P +  EV A+
Sbjct: 258 ALE---DGIGTFVLATDDPRTIRTFAEQVAPAVRIEVAAA 294


>sp|Q8PZ66|MER_METMA Tax_Id=2209 (mer)RecName:
           Full=5,10-methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11; AltName: Full=Coenzyme F420-dependent
           N(5),N(10)-methylenetetrahydromethanopterin reductase;
           AltName: Full=Methylene-H(4)MPT
           reductase;[Methanosarcina mazei]
          Length = 328

 Score = 97.1 bits (240), Expect = 3e-18
 Identities = 89/337 (26%), Positives = 141/337 (41%), Gaps = 44/337 (13%)

Query: 37  GADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRLG 96
           G D  WI DH N                         N + ++ L  LA     N +++G
Sbjct: 27  GFDYVWITDHYN-------------------------NRDVYSTLTVLALNT--NSIKIG 59

Query: 97  VCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGEREGNEPYGVEWSKPVARFEEGLA 156
             VT+   RNPA+TA + A++  ++ GRA+LG+G G++   +  G+ W KP+A  +E + 
Sbjct: 60  SGVTNSYTRNPAITASSIASIAEISGGRAVLGLGPGDKATFDAMGIAWEKPLATTKEAIQ 119

Query: 157 TIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPEIWVAAHGPRMLRATGRYADAWV 216
            IR   D     +  E   F      F      GK P I++ A GP+ML   G  AD  V
Sbjct: 120 AIRDFIDGKKVSMDGEMVKFAGAKLAFK----AGKIP-IYMGAQGPKMLELAGEVADG-V 173

Query: 217 PIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDEA-LDSVIVKM 275
            I    P D+  A+E +R  A   GRDP  +  +A         +D V       V+V  
Sbjct: 174 LINASHPKDFEVAVEQIRKGAEKVGRDPSEVDVTAY--ACFSIDKDPVKAVNAAKVVVAF 231

Query: 276 NALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRETVLSYTAKVPPGLIREVVASGTP 335
              G P     RHG+          + D I +  D  +++     V P +I      GTP
Sbjct: 232 IVAGSPDLVLERHGISVEAKKQ---IGDAIAKG-DFGSLMG--GLVTPQMIEAFSICGTP 285

Query: 336 DEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
           ++ + ++ +    G+    ++ GS + P   K +  +
Sbjct: 286 EDCMKRIKDLEAIGVTQ--IVAGSPIGPDKEKAIKLI 320


>tr|D1C9H9|D1C9H9_9CHLR Tax_Id=479434 SubName: Full=Putative
           F420-dependent oxidoreductase;[Sphaerobacter
           thermophilus DSM 20745]
          Length = 317

 Score = 95.9 bits (237), Expect = 8e-18
 Identities = 82/266 (30%), Positives = 117/266 (43%), Gaps = 30/266 (11%)

Query: 36  MGADSYWIGDHLNALVPRSVATPEFLGLGARLVPKVDANYEPWTMLGNLAAGNRINRLRL 95
           +G DS W+ DH     P     P                ++ WT+L  LAA     R+ +
Sbjct: 47  LGYDSLWVPDHFLMRFPGRTRPPR-------------GTWDCWTLLAALAATTE--RIEI 91

Query: 96  GVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGERE-GNEPYGVEWSKPVARFEEG 154
           G  V+    RNPA+ A  A TV  ++ GR ILG+G G+    +E  GV + +  +RFEE 
Sbjct: 92  GSLVSSTTFRNPALLAWIANTVDDVSGGRLILGVGAGDAPLEHEALGVPYDRRASRFEEA 151

Query: 155 LATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWPE-----IWVAAHGPRMLRATG 209
           +  I +L     +  T +  ++  R+A  +L P +G  P      I     GPRMLR   
Sbjct: 152 IQIITSLLRDGTS--TFDGTFYQTRDA--ELRP-RGPRPSGPPIMIGTGTRGPRMLRLAA 206

Query: 210 RYAD---AWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVRGVVTGWSRDDVDE 266
           RY D   AW+     +P       EAV AA  D GRDP ++  S V   V    R++  E
Sbjct: 207 RYGDMWNAWLAFGRSQPDAIPPLREAVDAACRDVGRDPATLARS-VAVQVDYLGREEYPE 265

Query: 267 ALDSVIVKMNALGMPAEAWARHGVEH 292
            L  +      L     A+A  G+ H
Sbjct: 266 GLAPLTGSPEDLAEQFRAFAHEGINH 291


>tr|D1C5U9|D1C5U9_9CHLR Tax_Id=479434 SubName: Full=Luciferase-like
           monooxygenase;[Sphaerobacter thermophilus DSM 20745]
          Length = 304

 Score = 95.9 bits (237), Expect = 8e-18
 Identities = 80/225 (35%), Positives = 108/225 (48%), Gaps = 14/225 (6%)

Query: 69  PKVDANYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILG 128
           P V  +Y+ WT+L  LA      R+RLG  V+ +  R PA+ A+AAA++ +L+ GR  LG
Sbjct: 44  PYVATHYDTWTLLTALAFTT--TRVRLGTNVSPLPLRPPAILAKAAASLDMLSGGRVELG 101

Query: 129 IGVGERE-GNEPYG---VEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFD 184
           IG G    G   +G   +E ++ VA FEEG+  IR LW S     T +  ++  R A F 
Sbjct: 102 IGAGGYPVGLRAFGADVLERAEIVAAFEEGIRVIRGLWTSERGF-TFDGEHYRTRGARFG 160

Query: 185 LPPYKGKWPEIWVAAHGPRMLRATGRYADA-WVPIVIIRPTDYSRALEAVRAAASDAGRD 243
             P +     IWV A  PRMLR  GR AD   V        D  R    V   A++AGR 
Sbjct: 161 PSPTRP--IPIWVGAARPRMLRLAGRLADGILVTNTFASVEDLPRINRWVDEGAAEAGRP 218

Query: 244 PMSITPSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARH 288
           P SI     RG     + D  D    S  ++ + L  PA  W  +
Sbjct: 219 PESIR----RGYNVMGAIDLADRPNRSDEIQADTLVFPAAGWVEY 259


>tr|Q6M159|Q6M159_METMP Tax_Id=39152 (mer)SubName: Full=Coenzyme
           F420-dependent N5,N10-methylenetetrahydromethanopterin
           reductase;[Methanococcus maripaludis]
          Length = 320

 Score = 95.9 bits (237), Expect = 8e-18
 Identities = 81/296 (27%), Positives = 126/296 (42%), Gaps = 35/296 (11%)

Query: 74  NYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGE 133
           N   +  LGNLAA    N+++LG  VT+   R+PA+ A A ATV  L+ GRA  GIG G+
Sbjct: 39  NRNVYMTLGNLAAAT--NKIKLGPGVTNPYVRSPAIAASAMATVDELSGGRATFGIGPGD 96

Query: 134 REGNEPYGVEWSKPVARFEEGLATIRAL-----WDSNGALVTRESPYFPLRNALFDLPPY 188
           +   +  G+EW+KPV   ++ +A  + L           L  + S   P           
Sbjct: 97  KATFDALGIEWTKPVGTIKKAIADFKELTAGKRMAEGAQLAVKPSAKIP----------- 145

Query: 189 KGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSIT 248
                 I++ A GP+ML   G  AD  V I    P D+  A+  ++  A  AGR    I 
Sbjct: 146 ------IYMGAQGPKMLETAGEIADG-VLINASNPKDFEAAVPLIKKGAEAAGRSMSEID 198

Query: 249 PSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQT 308
            +A   +      +   +A   V+  + A G P     RHG++           D I   
Sbjct: 199 VAAYACMSVDKKAEKAKQAAIPVVAFI-AAGSPPMILERHGID-------PAKVDAIRAG 250

Query: 309 MDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPS 364
           +      +    V   ++      GTP+EV+++V      G+    V+ GS + P+
Sbjct: 251 LKEGNFGAAFGNVDENMLEGFALYGTPEEVVEKVKALEKMGVTQ--VVAGSPIGPN 304


>tr|A9A8N4|A9A8N4_METM6 Tax_Id=444158 SubName:
           Full=5,10-methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11;[Methanococcus maripaludis]
          Length = 320

 Score = 95.9 bits (237), Expect = 8e-18
 Identities = 82/299 (27%), Positives = 130/299 (43%), Gaps = 25/299 (8%)

Query: 74  NYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGE 133
           N   +  LGNLAA    N+++LG  VT+   R+PA+ A A AT+  L+ GRA  GIG G+
Sbjct: 39  NRNVYMTLGNLAAAT--NKIKLGPGVTNPYVRSPAIAASAMATLDELSGGRATFGIGPGD 96

Query: 134 REGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWP 193
           +   +  G+EW+KPV    + +  ++AL          +    P            GK P
Sbjct: 97  KATFDALGIEWTKPVGTIIKAIDDMKALMAGKRLEEGAQLAVKP-----------SGKVP 145

Query: 194 EIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVR 253
            I++ A GP+ML   G  AD  V I    P D+  A+  ++  A  AGR    I  +A  
Sbjct: 146 -IYMGAQGPKMLETAGSIADG-VLINASNPKDFEAAVPLIKKGAEAAGRSMSEIDVAAYA 203

Query: 254 GVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRET 313
            +      D   +A   V+  + A G P     RHG++           D I   +    
Sbjct: 204 CMSVDKKADKAKQAAIPVVAFI-AAGSPPMILERHGID-------PAKVDAIRAGLKEGN 255

Query: 314 VLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
             +    V   ++      GTP+EV+++V      G+    V+ GS + P+   ++  +
Sbjct: 256 FGAAFGNVDEAMLEGFALYGTPEEVVEKVKGLEAMGVTQ--VVAGSPIGPNKETSIKLI 312


>tr|A6VI45|A6VI45_METM7 Tax_Id=426368 SubName:
           Full=5,10-methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11;[Methanococcus maripaludis]
          Length = 320

 Score = 95.9 bits (237), Expect = 8e-18
 Identities = 82/299 (27%), Positives = 130/299 (43%), Gaps = 25/299 (8%)

Query: 74  NYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGE 133
           N   +  LGNLAA    N+++LG  VT+   R+PA+ A A AT+  L+ GRA  GIG G+
Sbjct: 39  NRNVYMTLGNLAAAT--NKIKLGPGVTNPYVRSPAIAASAMATLDELSGGRATFGIGPGD 96

Query: 134 REGNEPYGVEWSKPVARFEEGLATIRALWDSNGALVTRESPYFPLRNALFDLPPYKGKWP 193
           +   +  G+EW+KPV    + +  ++AL          +    P            GK P
Sbjct: 97  KATFDALGIEWTKPVGTIIKAIDDMKALMAGKRLEEGAQLAVKP-----------SGKVP 145

Query: 194 EIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSITPSAVR 253
            I++ A GP+ML   G  AD  V I    P D+  A+  ++  A  AGR    I  +A  
Sbjct: 146 -IYMGAQGPKMLETAGSIADG-VLINASNPKDFEAAVPLIKKGAEAAGRSMSEIDVAAYA 203

Query: 254 GVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQTMDRET 313
            +      D   +A   V+  + A G P     RHG++           D I   +    
Sbjct: 204 CMSVDKKADKAKQAAIPVVAFI-AAGSPPMILERHGID-------PAKVDAIRAGLKEGN 255

Query: 314 VLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKTVTAV 372
             +    V   ++      GTP+EV+++V      G+    V+ GS + P+   ++  +
Sbjct: 256 FGAAFGNVDEAMLEGFALYGTPEEVVEKVKGLEAMGVTQ--VVAGSPIGPNKETSIKLI 312


>tr|A4G0D2|A4G0D2_METM5 Tax_Id=402880 SubName:
           Full=Methylenetetrahydromethanopterin reductase;
           EC=1.5.99.11;[Methanococcus maripaludis]
          Length = 320

 Score = 95.5 bits (236), Expect = 1e-17
 Identities = 80/304 (26%), Positives = 129/304 (42%), Gaps = 35/304 (11%)

Query: 74  NYEPWTMLGNLAAGNRINRLRLGVCVTDVGRRNPAVTAQAAATVHLLTRGRAILGIGVGE 133
           N   +  LGNLAA    N+++LG  VT+   R+PA+ A A ATV  L+ GRA  GIG G+
Sbjct: 39  NRNVYMTLGNLAAAT--NKIKLGPGVTNPYVRSPAIAASAMATVDELSGGRATFGIGPGD 96

Query: 134 REGNEPYGVEWSKPVARFEEGLATIRAL-----WDSNGALVTRESPYFPLRNALFDLPPY 188
           +   +  G+EW+KPV   ++ +A  + L           L  + S   P           
Sbjct: 97  KATFDALGIEWTKPVGTIKKAIADFKELTAGKRMAEGAQLAIKPSAKIP----------- 145

Query: 189 KGKWPEIWVAAHGPRMLRATGRYADAWVPIVIIRPTDYSRALEAVRAAASDAGRDPMSIT 248
                 I++ A GP+ML   G  AD  V I    P D+  A+  ++  A  AGR    I 
Sbjct: 146 ------IYMGAQGPKMLETAGEIADG-VLINASNPKDFEAAVPLIKKGAEAAGRSMSEID 198

Query: 249 PSAVRGVVTGWSRDDVDEALDSVIVKMNALGMPAEAWARHGVEHPMGADFTGVQDLIPQT 308
            +A   +      +   +A   V+  + A G P     RHG++           D I   
Sbjct: 199 VAAYACMSVDKKAEKAKQAAIPVVAFI-AAGSPPMILERHGID-------PAKVDAIRAG 250

Query: 309 MDRETVLSYTAKVPPGLIREVVASGTPDEVIDQVAEWRDHGLRYLLVINGSLVNPSLRKT 368
           +      +    V   ++      GTP+EV+++V      G+    ++ GS + P+   +
Sbjct: 251 LKEGNFGAAFGNVDEAMLEGFALYGTPEEVVEKVKALEAMGVTQ--IVAGSPIGPNKETS 308

Query: 369 VTAV 372
           +  +
Sbjct: 309 IKLI 312


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.319    0.136    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 3,052,575,087
Number of extensions: 132790332
Number of successful extensions: 311486
Number of sequences better than 10.0: 2037
Number of HSP's gapped: 312318
Number of HSP's successfully gapped: 2037
Length of query: 385
Length of database: 3,846,993,858
Length adjustment: 139
Effective length of query: 246
Effective length of database: 2,279,740,641
Effective search space: 560816197686
Effective search space used: 560816197686
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 81 (35.8 bits)