BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_1773 (1806 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HIM8|B2HIM8_MYCMM Tax_Id=216594 (ppsD)SubName: Full=Phenolp... 3238 0.0 tr|A0PQ36|A0PQ36_MYCUA Tax_Id=362242 (ppsD)SubName: Full=Phenolp... 3223 0.0 tr|Q7TXL7|Q7TXL7_MYCBO Tax_Id=1765 (ppsD)SubName: Full=PHENOLPTH... 2299 0.0 tr|C1AG50|C1AG50_MYCBT Tax_Id=561275 (ppsD)SubName: Full=Phenolp... 2299 0.0 tr|A1KMS9|A1KMS9_MYCBP Tax_Id=410289 (ppsD)SubName: Full=Phenolp... 2299 0.0 tr|P96203|P96203_MYCTU Tax_Id=1773 (ppsD)SubName: Full=PHENOLPTH... 2298 0.0 tr|A5U6U1|A5U6U1_MYCTA Tax_Id=419947 (ppsD)SubName: Full=Phenolp... 2298 0.0 tr|A5WRI6|A5WRI6_MYCTF Tax_Id=336982 SubName: Full=Phenolpthioce... 2298 0.0 tr|A2VLR1|A2VLR1_MYCTU Tax_Id=348776 SubName: Full=Phenolpthioce... 2298 0.0 tr|Q9CB70|Q9CB70_MYCLE Tax_Id=1769 SubName: Full=Polyketide synt... 2266 0.0 tr|B8ZT37|B8ZT37_MYCLB Tax_Id=561304 SubName: Full=Polyketide sy... 2266 0.0 tr|Q49940|Q49940_MYCLE Tax_Id=1769 SubName: Full=PksE;[Mycobacte... 2266 0.0 tr|A1T9S6|A1T9S6_MYCVP Tax_Id=350058 SubName: Full=Beta-ketoacyl... 1878 0.0 tr|A4TA92|A4TA92_MYCGI Tax_Id=350054 SubName: Full=Beta-ketoacyl... 1838 0.0 tr|C6DWC0|C6DWC0_MYCTK Tax_Id=478434 SubName: Full=Phenolpthioce... 1700 0.0 tr|A4KKJ4|A4KKJ4_MYCTU Tax_Id=395095 SubName: Full=Phenolpthioce... 1581 0.0 tr|B2HIM9|B2HIM9_MYCMM Tax_Id=216594 (ppsC)SubName: Full=Phenolp... 1087 0.0 tr|A0PQ37|A0PQ37_MYCUA Tax_Id=362242 (ppsC)SubName: Full=Phenolp... 1079 0.0 tr|Q49933|Q49933_MYCLE Tax_Id=1769 SubName: Full=Polyketide synt... 1075 0.0 tr|B8ZT38|B8ZT38_MYCLB Tax_Id=561304 SubName: Full=Polyketide sy... 1075 0.0 tr|Q7TXL8|Q7TXL8_MYCBO Tax_Id=1765 (ppsC)SubName: Full=PHENOLPTH... 1070 0.0 tr|P96202|P96202_MYCTU Tax_Id=1773 (ppsC)SubName: Full=PHENOLPTH... 1070 0.0 tr|C6DWC1|C6DWC1_MYCTK Tax_Id=478434 SubName: Full=Phenolpthioce... 1070 0.0 tr|C1AG49|C1AG49_MYCBT Tax_Id=561275 (ppsC)SubName: Full=Phenolp... 1070 0.0 tr|A5U6U0|A5U6U0_MYCTA Tax_Id=419947 (ppsC)SubName: Full=Phenolp... 1070 0.0 tr|A1KMS8|A1KMS8_MYCBP Tax_Id=410289 (ppsC)SubName: Full=Phenolp... 1070 0.0 tr|A5WRI5|A5WRI5_MYCTF Tax_Id=336982 SubName: Full=Phenolpthioce... 1070 0.0 tr|Q7D6F1|Q7D6F1_MYCTU Tax_Id=1773 SubName: Full=Polyketide synt... 1070 0.0 tr|A2VLR0|A2VLR0_MYCTU Tax_Id=348776 SubName: Full=Phenolpthioce... 1070 0.0 sp|Q10978|PPSB_MYCTU Tax_Id=1773 (ppsB)RecName: Full=Phenolpthio... 1058 0.0 tr|Q7TXL9|Q7TXL9_MYCBO Tax_Id=1765 (ppsB)SubName: Full=PHENOLPTH... 1058 0.0 tr|C6DWC2|C6DWC2_MYCTK Tax_Id=478434 SubName: Full=Phenolpthioce... 1058 0.0 tr|C1AG48|C1AG48_MYCBT Tax_Id=561275 (ppsB)SubName: Full=Phenolp... 1058 0.0 tr|A5U6T9|A5U6T9_MYCTA Tax_Id=419947 (ppsB)SubName: Full=Phenolp... 1058 0.0 tr|A1KMS7|A1KMS7_MYCBP Tax_Id=410289 (ppsB)SubName: Full=Phenolp... 1058 0.0 tr|A5WRI4|A5WRI4_MYCTF Tax_Id=336982 SubName: Full=Phenolpthioce... 1058 0.0 tr|A4KKJ2|A4KKJ2_MYCTU Tax_Id=395095 SubName: Full=Phenolpthioce... 1058 0.0 tr|A2VLQ9|A2VLQ9_MYCTU Tax_Id=348776 SubName: Full=Phenolpthioce... 1058 0.0 tr|Q9S384|Q9S384_MYCLE Tax_Id=1769 (MLCB12.01c)SubName: Full=Pol... 1051 0.0 tr|Q49932|Q49932_MYCLE Tax_Id=1769 SubName: Full=PksC;[Mycobacte... 1051 0.0 tr|B8ZT39|B8ZT39_MYCLB Tax_Id=561304 SubName: Full=Polyketide sy... 1050 0.0 tr|B2HIN0|B2HIN0_MYCMM Tax_Id=216594 (ppsB)SubName: Full=Phenolp... 1036 0.0 tr|A0PQ38|A0PQ38_MYCUA Tax_Id=362242 (ppsB)SubName: Full=Phenolp... 1027 0.0 tr|Q9Z5K6|Q9Z5K6_MYCLE Tax_Id=1769 (MLCB12.02c)SubName: Full=Pol... 1012 0.0 tr|B8ZT40|B8ZT40_MYCLB Tax_Id=561304 SubName: Full=Polyketide sy... 1012 0.0 sp|Q10977|PPSA_MYCTU Tax_Id=1773 (ppsA)RecName: Full=Phenolpthio... 1003 0.0 tr|A5U6T8|A5U6T8_MYCTA Tax_Id=419947 (ppsA)SubName: Full=Phenolp... 1003 0.0 tr|A4TA96|A4TA96_MYCGI Tax_Id=350054 SubName: Full=Acyl transfer... 994 0.0 tr|A5WRI3|A5WRI3_MYCTF Tax_Id=336982 SubName: Full=Phenolpthioce... 994 0.0 tr|A4KKJ1|A4KKJ1_MYCTU Tax_Id=395095 SubName: Full=Phenolpthioce... 994 0.0 >tr|B2HIM8|B2HIM8_MYCMM Tax_Id=216594 (ppsD)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsD;[Mycobacterium marinum] Length = 1806 Score = 3238 bits (8396), Expect = 0.0 Identities = 1657/1785 (92%), Positives = 1657/1785 (92%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL Sbjct: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKW TPREAVA Sbjct: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWGGFIDDVAGFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG Sbjct: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP Sbjct: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA Sbjct: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT Sbjct: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA Sbjct: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWPAGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQPRSGLSALVVSG 480 SSTRLFVPTQGAQWPAGLRRAAVSSFGLSGTNAHVVLEQ DQPRSGLSALVVSG Sbjct: 421 SSTRLFVPTQGAQWPAGLRRAAVSSFGLSGTNAHVVLEQPPAPAPADQPRSGLSALVVSG 480 Query: 481 KTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRA 540 KTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKF EGLRA Sbjct: 481 KTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFGAVVARDRAGAVEGLRA 540 Query: 541 LAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVA 600 LAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVA Sbjct: 541 LAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVA 600 Query: 601 QAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVV 660 QAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVV Sbjct: 601 QAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVV 660 Query: 661 AGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQS 720 AGALTPADGFKVIATRSRLMARLAGQG YPQVTLAVHASPHQS Sbjct: 661 AGALTPADGFKVIATRSRLMARLAGQGAMALLELDSDAAEALIADYPQVTLAVHASPHQS 720 Query: 721 VVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPM 780 VVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPM Sbjct: 721 VVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPM 780 Query: 781 ITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAA 840 ITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAA Sbjct: 781 ITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAA 840 Query: 841 AESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVEDRS 900 AESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVEDRS Sbjct: 841 AESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVEDRS 900 Query: 901 GISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXX 960 GISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMP Sbjct: 901 GISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPAAGFAEIALA 960 Query: 961 XXXXXFDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASGWRRHA 1020 FDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASGWRRHA Sbjct: 961 AASEAFDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASGWRRHA 1020 Query: 1021 VAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGS 1080 VAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGS Sbjct: 1021 VAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGS 1080 Query: 1081 VETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYS 1140 VETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYS Sbjct: 1081 VETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYS 1140 Query: 1141 NPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPLAQKI 1200 NPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPLAQKI Sbjct: 1141 NPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPLAQKI 1200 Query: 1201 FDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXXXXXX 1260 FDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDE Sbjct: 1201 FDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEAAMLAA 1260 Query: 1261 XXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVWQISTVVRAIVGTW 1320 GDPERLP RISYDGLIQSRDTVWQISTVVRAIVGTW Sbjct: 1261 FAETAGDPERLPVGVVVFVGGAGNNSGAADDGRISYDGLIQSRDTVWQISTVVRAIVGTW 1320 Query: 1321 HGRAPRLWLVTEGGLVVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRL 1380 HGRAPRLWLVTEGGLVVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRL Sbjct: 1321 HGRAPRLWLVTEGGLVVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRL 1380 Query: 1381 AGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXX 1440 AGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVT Sbjct: 1381 AGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTGGLGGLG 1440 Query: 1441 XVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAA 1500 VVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAA Sbjct: 1441 LVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAA 1500 Query: 1501 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS 1560 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS Sbjct: 1501 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS 1560 Query: 1561 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTPLDPI 1620 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTPLDPI Sbjct: 1561 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTPLDPI 1620 Query: 1621 TPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXX 1680 TPAEGVV RGRTGVARLRSDRALIAFPEIRNLGYFTLVVQEL Sbjct: 1621 TPAEGVVALDALLAADRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELDAAGDGGDWA 1680 Query: 1681 XPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTA 1740 PEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTA Sbjct: 1681 GPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTA 1740 Query: 1741 RADFGVEPPVTLILQGASLHDLTVDVIRQLDLAGDEQTHEHVDVV 1785 RADFGVEPPVTLILQGASLHDLTVDVIRQLDLAGDEQTHEHVDVV Sbjct: 1741 RADFGVEPPVTLILQGASLHDLTVDVIRQLDLAGDEQTHEHVDVV 1785 >tr|A0PQ36|A0PQ36_MYCUA Tax_Id=362242 (ppsD)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsD;[Mycobacterium ulcerans] Length = 1806 Score = 3223 bits (8357), Expect = 0.0 Identities = 1649/1785 (92%), Positives = 1653/1785 (92%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQMSPKAREVLA ELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL Sbjct: 1 MTSLAERAAQMSPKAREVLAHELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKW TPREAVA Sbjct: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWGGFIDDVAGFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG Sbjct: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP Sbjct: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA Sbjct: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT Sbjct: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA Sbjct: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWPAGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQPRSGLSALVVSG 480 SSTRLFVPTQGAQWPAGLRRAAVSSFGLSGTNAHVVLEQ DQPRSGLSALVVSG Sbjct: 421 SSTRLFVPTQGAQWPAGLRRAAVSSFGLSGTNAHVVLEQPPAPAPADQPRSGLSALVVSG 480 Query: 481 KTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRA 540 KTPQRVAAMASALADWVDGPG QTPLADVAHTLNHHRARHGKF EGLRA Sbjct: 481 KTPQRVAAMASALADWVDGPGAQTPLADVAHTLNHHRARHGKFGAVVARDRAGAVEGLRA 540 Query: 541 LAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVA 600 LAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVA Sbjct: 541 LAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVA 600 Query: 601 QAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVV 660 QAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVV Sbjct: 601 QAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVV 660 Query: 661 AGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQS 720 AGALTPADGFKVIATRSRLMARLAGQG YPQVTLAVHASPHQS Sbjct: 661 AGALTPADGFKVIATRSRLMARLAGQGAMALLELDSDAAEALIADYPQVTLAVHASPHQS 720 Query: 721 VVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPM 780 VVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPM Sbjct: 721 VVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPM 780 Query: 781 ITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAA 840 ITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAA Sbjct: 781 ITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAA 840 Query: 841 AESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVEDRS 900 A+SRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVEDRS Sbjct: 841 ADSRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVEDRS 900 Query: 901 GISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXX 960 GISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMP Sbjct: 901 GISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPAAGFAEIALA 960 Query: 961 XXXXXFDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASGWRRHA 1020 FDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASGWRRHA Sbjct: 961 AASEAFDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASGWRRHA 1020 Query: 1021 VAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGS 1080 VAKAETSTPSAAP LEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGS Sbjct: 1021 VAKAETSTPSAAPVLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGS 1080 Query: 1081 VETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYS 1140 VETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYS Sbjct: 1081 VETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYS 1140 Query: 1141 NPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPLAQKI 1200 NPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEI DIYLRRVERRSVPLPLAQKI Sbjct: 1141 NPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEITDIYLRRVERRSVPLPLAQKI 1200 Query: 1201 FDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXXXXXX 1260 FDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDE Sbjct: 1201 FDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEAAMLAA 1260 Query: 1261 XXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVWQISTVVRAIVGTW 1320 GDPERLP RISYDGLIQSRDTVWQISTVVRAIVGTW Sbjct: 1261 FAETAGDPERLPVGVVVFVGGAGNNSGTADDGRISYDGLIQSRDTVWQISTVVRAIVGTW 1320 Query: 1321 HGRAPRLWLVTEGGLVVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRL 1380 HGRAPRLWLVTEGGLVVHD+PGRPAIGALQGLVRVLAYEHPELRATLVDLDTGAD+VTRL Sbjct: 1321 HGRAPRLWLVTEGGLVVHDKPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADAVTRL 1380 Query: 1381 AGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXX 1440 AGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVT Sbjct: 1381 AGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTGGLGGLG 1440 Query: 1441 XVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAA 1500 VVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAA Sbjct: 1441 LVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAA 1500 Query: 1501 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS 1560 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS Sbjct: 1501 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS 1560 Query: 1561 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTPLDPI 1620 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTPLDPI Sbjct: 1561 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTPLDPI 1620 Query: 1621 TPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXX 1680 TPAEG+V RGRTGVARLRSDRALIAFPEIRNLGYFTLVVQEL Sbjct: 1621 TPAEGLVALDALLAADRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELDAAGDGGDWA 1680 Query: 1681 XPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTA 1740 PEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTA Sbjct: 1681 GPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTA 1740 Query: 1741 RADFGVEPPVTLILQGASLHDLTVDVIRQLDLAGDEQTHEHVDVV 1785 RADFGVEPPVTLILQGASLHDLTVDVIRQLDLAGDEQTHEHVDVV Sbjct: 1741 RADFGVEPPVTLILQGASLHDLTVDVIRQLDLAGDEQTHEHVDVV 1785 >tr|Q7TXL7|Q7TXL7_MYCBO Tax_Id=1765 (ppsD)SubName: Full=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD;[Mycobacterium bovis] Length = 1827 Score = 2299 bits (5958), Expect = 0.0 Identities = 1195/1813 (65%), Positives = 1355/1813 (74%), Gaps = 41/1813 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVRAGT FPTDI EPVAVVGIGCR PGNV+GP+SFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L DG D +++VP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWEALEHAG+PPDSLSGTRT +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRILLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRI+YLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+DVALAGGVQL LSP Sbjct: 181 TPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRL DAVRD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 N DGRSNGMTAPNA AQRDVI +ALKLAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGK +G CALGSVKTN+GHLEAAAG+ FIKA LAV G+IP NLHF+RWNPAIDA Sbjct: 361 YGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ-PRSGLSALV 477 S+TRLFVPT+ A WP AG RRAAVSSFGLSGTNAHVV+EQ +SAL Sbjct: 421 SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALN 480 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HRARH KF G Sbjct: 481 VSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAG 540 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQP GV+ C PG VFVYSGQGSQW MG+QLLA+EP+FA A+AEL+P Sbjct: 541 LRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPI 600 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGEVSA Sbjct: 601 FVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSA 660 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAGALTP G +VI TRSRLMARL+GQG YPQVTLAVHASP Sbjct: 661 AVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASP 720 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPIIDPILP+LRSALADLTPQPP+ Sbjct: 721 RQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPS 780 Query: 778 IPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDT 837 IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG H+TF+EISPHP+LTHA+TDT Sbjct: 781 IPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT 840 Query: 838 LAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVE 897 L S T + +T+ R+ D + FH LAAVG ++ TG+L D+P TPW H +FWV Sbjct: 841 LDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVT 898 Query: 898 DRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXX 957 DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPWL DHKVFGQ IMP Sbjct: 899 DRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEI 958 Query: 958 XXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA 1013 DA++ INQ E+EQML LD HT +TTQL R D + R+EIYSR+ Sbjct: 959 ALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTR 1018 Query: 1014 SG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTR 1072 G + RHA AK E S A E T + PAD YALLRQ GQ+HGPAFAAL+R Sbjct: 1019 GGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSR 1078 Query: 1073 ILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVS 1132 I+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ AA+P+ E AGSAEASYLPVS Sbjct: 1079 IVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVS 1138 Query: 1133 FETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSV 1192 FET+RVY + GRH RCRA LTNL DGG GK+GRI L +DAG++ E++ IYLRRVERR+V Sbjct: 1139 FETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAV 1197 Query: 1193 PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----------AKSNADEFVA 1237 PLPL QKIFD EW E IA P+ GSWLVL D AKS AD+FV Sbjct: 1198 PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQ 1257 Query: 1238 RWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYD 1297 +W SP RRV TAD+ DE GDPE P D Sbjct: 1258 QWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLD---------D 1308 Query: 1298 GLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVL 1356 L +RDTVW I+TVVRA+VGTWHGR+PRLWLVT GGL V DEPG PA +L+GLVRVL Sbjct: 1309 ELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVL 1368 Query: 1357 AYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDP 1416 A+EHP++R TLVDLD D +T L+ EL + +DDV+AWR R+V +L RA +D Sbjct: 1369 AFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDV 1428 Query: 1417 EPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES 1476 + PV+R GASY+VT VVARWLVD GAGRVVL GRS+P+DEQ VLAEL++ Sbjct: 1429 S-KGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGGRSDPTDEQCNVLAELQT 1487 Query: 1477 RAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAP 1536 RAE+VVV GD A+ GVAE L+ A QLRG+VH AAVI+DSL+FSM++D+LERVWAP Sbjct: 1488 RAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDNLERVWAP 1547 Query: 1537 KAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAA 1596 KA GALR+H+ATA ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WRRA+GLPAA Sbjct: 1548 KATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAA 1607 Query: 1597 TINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPE 1656 INWGPWSEVGVAQALVG+ LD I+ AEG+ R RTGVARLR+DRAL+AFPE Sbjct: 1608 VINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPE 1667 Query: 1657 IRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA 1716 IR++ YFT VV+EL P+AL ++DP EAR+ VTER+ RIAAVMGY D+S Sbjct: 1668 IRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST 1727 Query: 1717 VDASM----PLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDL 1772 V+ ++ PLTELGLDSLMAVRIRN ARADFGVEPPV LILQGASLHDLT D++RQL L Sbjct: 1728 VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDLTADLMRQLGL 1787 Query: 1773 AGDEQTHEHVDVV 1785 + + D + Sbjct: 1788 NDPDPALNNADTI 1800 >tr|C1AG50|C1AG50_MYCBT Tax_Id=561275 (ppsD)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase;[Mycobacterium bovis] Length = 1827 Score = 2299 bits (5958), Expect = 0.0 Identities = 1195/1813 (65%), Positives = 1355/1813 (74%), Gaps = 41/1813 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVRAGT FPTDI EPVAVVGIGCR PGNV+GP+SFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L DG D +++VP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWEALEHAG+PPDSLSGTRT +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRILLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRI+YLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+DVALAGGVQL LSP Sbjct: 181 TPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRL DAVRD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 N DGRSNGMTAPNA AQRDVI +ALKLAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGK +G CALGSVKTN+GHLEAAAG+ FIKA LAV G+IP NLHF+RWNPAIDA Sbjct: 361 YGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ-PRSGLSALV 477 S+TRLFVPT+ A WP AG RRAAVSSFGLSGTNAHVV+EQ +SAL Sbjct: 421 SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALN 480 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HRARH KF G Sbjct: 481 VSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAG 540 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQP GV+ C PG VFVYSGQGSQW MG+QLLA+EP+FA A+AEL+P Sbjct: 541 LRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPI 600 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGEVSA Sbjct: 601 FVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSA 660 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAGALTP G +VI TRSRLMARL+GQG YPQVTLAVHASP Sbjct: 661 AVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASP 720 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPIIDPILP+LRSALADLTPQPP+ Sbjct: 721 RQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPS 780 Query: 778 IPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDT 837 IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG H+TF+EISPHP+LTHA+TDT Sbjct: 781 IPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT 840 Query: 838 LAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVE 897 L S T + +T+ R+ D + FH LAAVG ++ TG+L D+P TPW H +FWV Sbjct: 841 LDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVT 898 Query: 898 DRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXX 957 DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPWL DHKVFGQ IMP Sbjct: 899 DRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEI 958 Query: 958 XXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA 1013 DA++ INQ E+EQML LD HT +TTQL R D + R+EIYSR+ Sbjct: 959 ALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTR 1018 Query: 1014 SG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTR 1072 G + RHA AK E S A E T + PAD YALLRQ GQ+HGPAFAAL+R Sbjct: 1019 GGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSR 1078 Query: 1073 ILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVS 1132 I+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ AA+P+ E AGSAEASYLPVS Sbjct: 1079 IVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVS 1138 Query: 1133 FETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSV 1192 FET+RVY + GRH RCRA LTNL DGG GK+GRI L +DAG++ E++ IYLRRVERR+V Sbjct: 1139 FETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAV 1197 Query: 1193 PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----------AKSNADEFVA 1237 PLPL QKIFD EW E IA P+ GSWLVL D AKS AD+FV Sbjct: 1198 PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQ 1257 Query: 1238 RWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYD 1297 +W SP RRV TAD+ DE GDPE P D Sbjct: 1258 QWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLD---------D 1308 Query: 1298 GLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVL 1356 L +RDTVW I+TVVRA+VGTWHGR+PRLWLVT GGL V DEPG PA +L+GLVRVL Sbjct: 1309 ELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVL 1368 Query: 1357 AYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDP 1416 A+EHP++R TLVDLD D +T L+ EL + +DDV+AWR R+V +L RA +D Sbjct: 1369 AFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDV 1428 Query: 1417 EPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES 1476 + PV+R GASY+VT VVARWLVD GAGRVVL GRS+P+DEQ VLAEL++ Sbjct: 1429 S-KGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGGRSDPTDEQCNVLAELQT 1487 Query: 1477 RAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAP 1536 RAE+VVV GD A+ GVAE L+ A QLRG+VH AAVI+DSL+FSM++D+LERVWAP Sbjct: 1488 RAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDNLERVWAP 1547 Query: 1537 KAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAA 1596 KA GALR+H+ATA ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WRRA+GLPAA Sbjct: 1548 KATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAA 1607 Query: 1597 TINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPE 1656 INWGPWSEVGVAQALVG+ LD I+ AEG+ R RTGVARLR+DRAL+AFPE Sbjct: 1608 VINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPE 1667 Query: 1657 IRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA 1716 IR++ YFT VV+EL P+AL ++DP EAR+ VTER+ RIAAVMGY D+S Sbjct: 1668 IRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST 1727 Query: 1717 VDASM----PLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDL 1772 V+ ++ PLTELGLDSLMAVRIRN ARADFGVEPPV LILQGASLHDLT D++RQL L Sbjct: 1728 VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDLTADLMRQLGL 1787 Query: 1773 AGDEQTHEHVDVV 1785 + + D + Sbjct: 1788 NDPDPALNNADTI 1800 >tr|A1KMS9|A1KMS9_MYCBP Tax_Id=410289 (ppsD)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsD;[Mycobacterium bovis] Length = 1827 Score = 2299 bits (5958), Expect = 0.0 Identities = 1195/1813 (65%), Positives = 1355/1813 (74%), Gaps = 41/1813 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVRAGT FPTDI EPVAVVGIGCR PGNV+GP+SFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L DG D +++VP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWEALEHAG+PPDSLSGTRT +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRILLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRI+YLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+DVALAGGVQL LSP Sbjct: 181 TPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRL DAVRD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 N DGRSNGMTAPNA AQRDVI +ALKLAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGK +G CALGSVKTN+GHLEAAAG+ FIKA LAV G+IP NLHF+RWNPAIDA Sbjct: 361 YGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ-PRSGLSALV 477 S+TRLFVPT+ A WP AG RRAAVSSFGLSGTNAHVV+EQ +SAL Sbjct: 421 SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALN 480 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HRARH KF G Sbjct: 481 VSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAG 540 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQP GV+ C PG VFVYSGQGSQW MG+QLLA+EP+FA A+AEL+P Sbjct: 541 LRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPI 600 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGEVSA Sbjct: 601 FVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSA 660 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAGALTP G +VI TRSRLMARL+GQG YPQVTLAVHASP Sbjct: 661 AVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASP 720 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPIIDPILP+LRSALADLTPQPP+ Sbjct: 721 RQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPS 780 Query: 778 IPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDT 837 IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG H+TF+EISPHP+LTHA+TDT Sbjct: 781 IPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT 840 Query: 838 LAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVE 897 L S T + +T+ R+ D + FH LAAVG ++ TG+L D+P TPW H +FWV Sbjct: 841 LDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVT 898 Query: 898 DRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXX 957 DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPWL DHKVFGQ IMP Sbjct: 899 DRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEI 958 Query: 958 XXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA 1013 DA++ INQ E+EQML LD HT +TTQL R D + R+EIYSR+ Sbjct: 959 ALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTR 1018 Query: 1014 SG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTR 1072 G + RHA AK E S A E T + PAD YALLRQ GQ+HGPAFAAL+R Sbjct: 1019 GGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSR 1078 Query: 1073 ILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVS 1132 I+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ AA+P+ E AGSAEASYLPVS Sbjct: 1079 IVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVS 1138 Query: 1133 FETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSV 1192 FET+RVY + GRH RCRA LTNL DGG GK+GRI L +DAG++ E++ IYLRRVERR+V Sbjct: 1139 FETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAV 1197 Query: 1193 PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----------AKSNADEFVA 1237 PLPL QKIFD EW E IA P+ GSWLVL D AKS AD+FV Sbjct: 1198 PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQ 1257 Query: 1238 RWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYD 1297 +W SP RRV TAD+ DE GDPE P D Sbjct: 1258 QWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLD---------D 1308 Query: 1298 GLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVL 1356 L +RDTVW I+TVVRA+VGTWHGR+PRLWLVT GGL V DEPG PA +L+GLVRVL Sbjct: 1309 ELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVL 1368 Query: 1357 AYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDP 1416 A+EHP++R TLVDLD D +T L+ EL + +DDV+AWR R+V +L RA +D Sbjct: 1369 AFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDV 1428 Query: 1417 EPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES 1476 + PV+R GASY+VT VVARWLVD GAGRVVL GRS+P+DEQ VLAEL++ Sbjct: 1429 S-KGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGGRSDPTDEQCNVLAELQT 1487 Query: 1477 RAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAP 1536 RAE+VVV GD A+ GVAE L+ A QLRG+VH AAVI+DSL+FSM++D+LERVWAP Sbjct: 1488 RAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDNLERVWAP 1547 Query: 1537 KAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAA 1596 KA GALR+H+ATA ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WRRA+GLPAA Sbjct: 1548 KATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAA 1607 Query: 1597 TINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPE 1656 INWGPWSEVGVAQALVG+ LD I+ AEG+ R RTGVARLR+DRAL+AFPE Sbjct: 1608 VINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPE 1667 Query: 1657 IRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA 1716 IR++ YFT VV+EL P+AL ++DP EAR+ VTER+ RIAAVMGY D+S Sbjct: 1668 IRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST 1727 Query: 1717 VDASM----PLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDL 1772 V+ ++ PLTELGLDSLMAVRIRN ARADFGVEPPV LILQGASLHDLT D++RQL L Sbjct: 1728 VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDLTADLMRQLGL 1787 Query: 1773 AGDEQTHEHVDVV 1785 + + D + Sbjct: 1788 NDPDPALNNADTI 1800 >tr|P96203|P96203_MYCTU Tax_Id=1773 (ppsD)SubName: Full=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD; SubName: Full=Polyketide synthase;[Mycobacterium tuberculosis] Length = 1827 Score = 2298 bits (5956), Expect = 0.0 Identities = 1195/1813 (65%), Positives = 1355/1813 (74%), Gaps = 41/1813 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVRAGT FPTDI EPVAVVGIGCR PGNV+GP+SFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L DG D +++VP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWEALEHAG+PPDSLSGTRT +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRMLLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRI+YLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+DVALAGGVQL LSP Sbjct: 181 TPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRL DAVRD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 N DGRSNGMTAPNA AQRDVI +ALKLAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGK +G CALGSVKTN+GHLEAAAG+ FIKA LAV G+IP NLHF+RWNPAIDA Sbjct: 361 YGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ-PRSGLSALV 477 S+TRLFVPT+ A WP AG RRAAVSSFGLSGTNAHVV+EQ +SAL Sbjct: 421 SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALN 480 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HRARH KF G Sbjct: 481 VSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAG 540 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQP GV+ C PG VFVYSGQGSQW MG+QLLA+EP+FA A+AEL+P Sbjct: 541 LRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPI 600 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGEVSA Sbjct: 601 FVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSA 660 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAGALTP G +VI TRSRLMARL+GQG YPQVTLAVHASP Sbjct: 661 AVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASP 720 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPIIDPILP+LRSALADLTPQPP+ Sbjct: 721 RQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPS 780 Query: 778 IPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDT 837 IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG H+TF+EISPHP+LTHA+TDT Sbjct: 781 IPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT 840 Query: 838 LAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVE 897 L S T + +T+ R+ D + FH LAAVG ++ TG+L D+P TPW H +FWV Sbjct: 841 LDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVT 898 Query: 898 DRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXX 957 DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPWL DHKVFGQ IMP Sbjct: 899 DRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEI 958 Query: 958 XXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA 1013 DA++ INQ E+EQML LD HT +TTQL R D + R+EIYSR+ Sbjct: 959 ALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTR 1018 Query: 1014 SG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTR 1072 G + RHA AK E S A E T + PAD YALLRQ GQ+HGPAFAAL+R Sbjct: 1019 GGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSR 1078 Query: 1073 ILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVS 1132 I+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ AA+P+ E AGSAEASYLPVS Sbjct: 1079 IVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVS 1138 Query: 1133 FETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSV 1192 FET+RVY + GRH RCRA LTNL DGG GK+GRI L +DAG++ E++ IYLRRVERR+V Sbjct: 1139 FETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAV 1197 Query: 1193 PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----------AKSNADEFVA 1237 PLPL QKIFD EW E IA P+ GSWLVL D AKS AD+FV Sbjct: 1198 PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQ 1257 Query: 1238 RWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYD 1297 +W SP RRV TAD+ DE GDPE P D Sbjct: 1258 QWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLD---------D 1308 Query: 1298 GLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVL 1356 L +RDTVW I+TVVRA+VGTWHGR+PRLWLVT GGL V DEPG PA +L+GLVRVL Sbjct: 1309 ELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVL 1368 Query: 1357 AYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDP 1416 A+EHP++R TLVDLD D +T L+ EL + +DDV+AWR R+V +L RA +D Sbjct: 1369 AFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDV 1428 Query: 1417 EPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES 1476 + PV+R GASY+VT VVARWLVD GAGRVVL GRS+P+DEQ VLAEL++ Sbjct: 1429 S-KGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGGRSDPTDEQCNVLAELQT 1487 Query: 1477 RAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAP 1536 RAE+VVV GD A+ GVAE L+ A QLRG+VH AAVI+DSL+FSM++D+LERVWAP Sbjct: 1488 RAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDNLERVWAP 1547 Query: 1537 KAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAA 1596 KA GALR+H+ATA ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WRRA+GLPAA Sbjct: 1548 KATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAA 1607 Query: 1597 TINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPE 1656 INWGPWSEVGVAQALVG+ LD I+ AEG+ R RTGVARLR+DRAL+AFPE Sbjct: 1608 VINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPE 1667 Query: 1657 IRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA 1716 IR++ YFT VV+EL P+AL ++DP EAR+ VTER+ RIAAVMGY D+S Sbjct: 1668 IRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST 1727 Query: 1717 VDASM----PLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDL 1772 V+ ++ PLTELGLDSLMAVRIRN ARADFGVEPPV LILQGASLHDLT D++RQL L Sbjct: 1728 VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDLTADLMRQLGL 1787 Query: 1773 AGDEQTHEHVDVV 1785 + + D + Sbjct: 1788 NDPDPALNNADTI 1800 >tr|A5U6U1|A5U6U1_MYCTA Tax_Id=419947 (ppsD)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsD;[Mycobacterium tuberculosis] Length = 1827 Score = 2298 bits (5956), Expect = 0.0 Identities = 1195/1813 (65%), Positives = 1355/1813 (74%), Gaps = 41/1813 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVRAGT FPTDI EPVAVVGIGCR PGNV+GP+SFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L DG D +++VP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWEALEHAG+PPDSLSGTRT +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRMLLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRI+YLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+DVALAGGVQL LSP Sbjct: 181 TPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRL DAVRD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 N DGRSNGMTAPNA AQRDVI +ALKLAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGK +G CALGSVKTN+GHLEAAAG+ FIKA LAV G+IP NLHF+RWNPAIDA Sbjct: 361 YGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ-PRSGLSALV 477 S+TRLFVPT+ A WP AG RRAAVSSFGLSGTNAHVV+EQ +SAL Sbjct: 421 SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALN 480 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HRARH KF G Sbjct: 481 VSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAG 540 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQP GV+ C PG VFVYSGQGSQW MG+QLLA+EP+FA A+AEL+P Sbjct: 541 LRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPI 600 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGEVSA Sbjct: 601 FVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSA 660 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAGALTP G +VI TRSRLMARL+GQG YPQVTLAVHASP Sbjct: 661 AVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASP 720 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPIIDPILP+LRSALADLTPQPP+ Sbjct: 721 RQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPS 780 Query: 778 IPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDT 837 IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG H+TF+EISPHP+LTHA+TDT Sbjct: 781 IPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT 840 Query: 838 LAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVE 897 L S T + +T+ R+ D + FH LAAVG ++ TG+L D+P TPW H +FWV Sbjct: 841 LDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVT 898 Query: 898 DRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXX 957 DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPWL DHKVFGQ IMP Sbjct: 899 DRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEI 958 Query: 958 XXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA 1013 DA++ INQ E+EQML LD HT +TTQL R D + R+EIYSR+ Sbjct: 959 ALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTR 1018 Query: 1014 SG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTR 1072 G + RHA AK E S A E T + PAD YALLRQ GQ+HGPAFAAL+R Sbjct: 1019 GGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSR 1078 Query: 1073 ILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVS 1132 I+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ AA+P+ E AGSAEASYLPVS Sbjct: 1079 IVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVS 1138 Query: 1133 FETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSV 1192 FET+RVY + GRH RCRA LTNL DGG GK+GRI L +DAG++ E++ IYLRRVERR+V Sbjct: 1139 FETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAV 1197 Query: 1193 PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----------AKSNADEFVA 1237 PLPL QKIFD EW E IA P+ GSWLVL D AKS AD+FV Sbjct: 1198 PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQ 1257 Query: 1238 RWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYD 1297 +W SP RRV TAD+ DE GDPE P D Sbjct: 1258 QWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLD---------D 1308 Query: 1298 GLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVL 1356 L +RDTVW I+TVVRA+VGTWHGR+PRLWLVT GGL V DEPG PA +L+GLVRVL Sbjct: 1309 ELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVL 1368 Query: 1357 AYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDP 1416 A+EHP++R TLVDLD D +T L+ EL + +DDV+AWR R+V +L RA +D Sbjct: 1369 AFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDV 1428 Query: 1417 EPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES 1476 + PV+R GASY+VT VVARWLVD GAGRVVL GRS+P+DEQ VLAEL++ Sbjct: 1429 S-KGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGGRSDPTDEQCNVLAELQT 1487 Query: 1477 RAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAP 1536 RAE+VVV GD A+ GVAE L+ A QLRG+VH AAVI+DSL+FSM++D+LERVWAP Sbjct: 1488 RAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDNLERVWAP 1547 Query: 1537 KAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAA 1596 KA GALR+H+ATA ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WRRA+GLPAA Sbjct: 1548 KATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAA 1607 Query: 1597 TINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPE 1656 INWGPWSEVGVAQALVG+ LD I+ AEG+ R RTGVARLR+DRAL+AFPE Sbjct: 1608 VINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPE 1667 Query: 1657 IRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA 1716 IR++ YFT VV+EL P+AL ++DP EAR+ VTER+ RIAAVMGY D+S Sbjct: 1668 IRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST 1727 Query: 1717 VDASM----PLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDL 1772 V+ ++ PLTELGLDSLMAVRIRN ARADFGVEPPV LILQGASLHDLT D++RQL L Sbjct: 1728 VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDLTADLMRQLGL 1787 Query: 1773 AGDEQTHEHVDVV 1785 + + D + Sbjct: 1788 NDPDPALNNADTI 1800 >tr|A5WRI6|A5WRI6_MYCTF Tax_Id=336982 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsD;[Mycobacterium tuberculosis] Length = 1827 Score = 2298 bits (5956), Expect = 0.0 Identities = 1195/1813 (65%), Positives = 1355/1813 (74%), Gaps = 41/1813 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVRAGT FPTDI EPVAVVGIGCR PGNV+GP+SFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L DG D +++VP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWEALEHAG+PPDSLSGTRT +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRMLLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRI+YLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+DVALAGGVQL LSP Sbjct: 181 TPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRL DAVRD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 N DGRSNGMTAPNA AQRDVI +ALKLAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGK +G CALGSVKTN+GHLEAAAG+ FIKA LAV G+IP NLHF+RWNPAIDA Sbjct: 361 YGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ-PRSGLSALV 477 S+TRLFVPT+ A WP AG RRAAVSSFGLSGTNAHVV+EQ +SAL Sbjct: 421 SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALN 480 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HRARH KF G Sbjct: 481 VSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAG 540 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQP GV+ C PG VFVYSGQGSQW MG+QLLA+EP+FA A+AEL+P Sbjct: 541 LRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPI 600 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGEVSA Sbjct: 601 FVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSA 660 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAGALTP G +VI TRSRLMARL+GQG YPQVTLAVHASP Sbjct: 661 AVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASP 720 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPIIDPILP+LRSALADLTPQPP+ Sbjct: 721 RQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPS 780 Query: 778 IPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDT 837 IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG H+TF+EISPHP+LTHA+TDT Sbjct: 781 IPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT 840 Query: 838 LAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVE 897 L S T + +T+ R+ D + FH LAAVG ++ TG+L D+P TPW H +FWV Sbjct: 841 LDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVT 898 Query: 898 DRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXX 957 DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPWL DHKVFGQ IMP Sbjct: 899 DRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEI 958 Query: 958 XXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA 1013 DA++ INQ E+EQML LD HT +TTQL R D + R+EIYSR+ Sbjct: 959 ALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTR 1018 Query: 1014 SG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTR 1072 G + RHA AK E S A E T + PAD YALLRQ GQ+HGPAFAAL+R Sbjct: 1019 GGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSR 1078 Query: 1073 ILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVS 1132 I+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ AA+P+ E AGSAEASYLPVS Sbjct: 1079 IVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVS 1138 Query: 1133 FETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSV 1192 FET+RVY + GRH RCRA LTNL DGG GK+GRI L +DAG++ E++ IYLRRVERR+V Sbjct: 1139 FETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAV 1197 Query: 1193 PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----------AKSNADEFVA 1237 PLPL QKIFD EW E IA P+ GSWLVL D AKS AD+FV Sbjct: 1198 PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQ 1257 Query: 1238 RWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYD 1297 +W SP RRV TAD+ DE GDPE P D Sbjct: 1258 QWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLD---------D 1308 Query: 1298 GLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVL 1356 L +RDTVW I+TVVRA+VGTWHGR+PRLWLVT GGL V DEPG PA +L+GLVRVL Sbjct: 1309 ELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVL 1368 Query: 1357 AYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDP 1416 A+EHP++R TLVDLD D +T L+ EL + +DDV+AWR R+V +L RA +D Sbjct: 1369 AFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDV 1428 Query: 1417 EPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES 1476 + PV+R GASY+VT VVARWLVD GAGRVVL GRS+P+DEQ VLAEL++ Sbjct: 1429 S-KGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGGRSDPTDEQCNVLAELQT 1487 Query: 1477 RAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAP 1536 RAE+VVV GD A+ GVAE L+ A QLRG+VH AAVI+DSL+FSM++D+LERVWAP Sbjct: 1488 RAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDNLERVWAP 1547 Query: 1537 KAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAA 1596 KA GALR+H+ATA ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WRRA+GLPAA Sbjct: 1548 KATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAA 1607 Query: 1597 TINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPE 1656 INWGPWSEVGVAQALVG+ LD I+ AEG+ R RTGVARLR+DRAL+AFPE Sbjct: 1608 VINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPE 1667 Query: 1657 IRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA 1716 IR++ YFT VV+EL P+AL ++DP EAR+ VTER+ RIAAVMGY D+S Sbjct: 1668 IRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST 1727 Query: 1717 VDASM----PLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDL 1772 V+ ++ PLTELGLDSLMAVRIRN ARADFGVEPPV LILQGASLHDLT D++RQL L Sbjct: 1728 VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDLTADLMRQLGL 1787 Query: 1773 AGDEQTHEHVDVV 1785 + + D + Sbjct: 1788 NDPDPALNNADTI 1800 >tr|A2VLR1|A2VLR1_MYCTU Tax_Id=348776 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsD;[Mycobacterium tuberculosis C] Length = 1827 Score = 2298 bits (5956), Expect = 0.0 Identities = 1195/1813 (65%), Positives = 1355/1813 (74%), Gaps = 41/1813 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVRAGT FPTDI EPVAVVGIGCR PGNV+GP+SFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L DG D +++VP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWEALEHAG+PPDSLSGTRT +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRMLLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRI+YLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+DVALAGGVQL LSP Sbjct: 181 TPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRL DAVRD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 N DGRSNGMTAPNA AQRDVI +ALKLAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGK +G CALGSVKTN+GHLEAAAG+ FIKA LAV G+IP NLHF+RWNPAIDA Sbjct: 361 YGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ-PRSGLSALV 477 S+TRLFVPT+ A WP AG RRAAVSSFGLSGTNAHVV+EQ +SAL Sbjct: 421 SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALN 480 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HRARH KF G Sbjct: 481 VSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAG 540 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQP GV+ C PG VFVYSGQGSQW MG+QLLA+EP+FA A+AEL+P Sbjct: 541 LRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPI 600 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGEVSA Sbjct: 601 FVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSA 660 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAGALTP G +VI TRSRLMARL+GQG YPQVTLAVHASP Sbjct: 661 AVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASP 720 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPIIDPILP+LRSALADLTPQPP+ Sbjct: 721 RQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPS 780 Query: 778 IPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDT 837 IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG H+TF+EISPHP+LTHA+TDT Sbjct: 781 IPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT 840 Query: 838 LAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVE 897 L S T + +T+ R+ D + FH LAAVG ++ TG+L D+P TPW H +FWV Sbjct: 841 LDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVT 898 Query: 898 DRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXX 957 DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPWL DHKVFGQ IMP Sbjct: 899 DRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEI 958 Query: 958 XXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA 1013 DA++ INQ E+EQML LD HT +TTQL R D + R+EIYSR+ Sbjct: 959 ALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTR 1018 Query: 1014 SG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTR 1072 G + RHA AK E S A E T + PAD YALLRQ GQ+HGPAFAAL+R Sbjct: 1019 GGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSR 1078 Query: 1073 ILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVS 1132 I+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ AA+P+ E AGSAEASYLPVS Sbjct: 1079 IVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVS 1138 Query: 1133 FETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSV 1192 FET+RVY + GRH RCRA LTNL DGG GK+GRI L +DAG++ E++ IYLRRVERR+V Sbjct: 1139 FETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAV 1197 Query: 1193 PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----------AKSNADEFVA 1237 PLPL QKIFD EW E IA P+ GSWLVL D AKS AD+FV Sbjct: 1198 PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQ 1257 Query: 1238 RWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYD 1297 +W SP RRV TAD+ DE GDPE P D Sbjct: 1258 QWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVVFVGGASSRLD---------D 1308 Query: 1298 GLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVL 1356 L +RDTVW I+TVVRA+VGTWHGR+PRLWLVT GGL V DEPG PA +L+GLVRVL Sbjct: 1309 ELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSVADDEPGTPAAASLKGLVRVL 1368 Query: 1357 AYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDP 1416 A+EHP++R TLVDLD D +T L+ EL + +DDV+AWR R+V +L RA +D Sbjct: 1369 AFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDVIAWRGERRFVERLSRATIDV 1428 Query: 1417 EPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES 1476 + PV+R GASY+VT VVARWLVD GAGRVVL GRS+P+DEQ VLAEL++ Sbjct: 1429 S-KGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVVLGGRSDPTDEQCNVLAELQT 1487 Query: 1477 RAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAP 1536 RAE+VVV GD A+ GVAE L+ A QLRG+VH AAVI+DSL+FSM++D+LERVWAP Sbjct: 1488 RAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAVIEDSLVFSMSRDNLERVWAP 1547 Query: 1537 KAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAA 1596 KA GALR+H+ATA ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WRRA+GLPAA Sbjct: 1548 KATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYACASAWLDALVGWRRASGLPAA 1607 Query: 1597 TINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPE 1656 INWGPWSEVGVAQALVG+ LD I+ AEG+ R RTGVARLR+DRAL+AFPE Sbjct: 1608 VINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPE 1667 Query: 1657 IRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSA 1716 IR++ YFT VV+EL P+AL ++DP EAR+ VTER+ RIAAVMGY D+S Sbjct: 1668 IRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAVMGYTDQST 1727 Query: 1717 VDASM----PLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDL 1772 V+ ++ PLTELGLDSLMAVRIRN ARADFGVEPPV LILQGASLHDLT D++RQL L Sbjct: 1728 VEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQGASLHDLTADLMRQLGL 1787 Query: 1773 AGDEQTHEHVDVV 1785 + + D + Sbjct: 1788 NDPDPALNNADTI 1800 >tr|Q9CB70|Q9CB70_MYCLE Tax_Id=1769 SubName: Full=Polyketide synthase;[Mycobacterium leprae] Length = 1822 Score = 2266 bits (5872), Expect = 0.0 Identities = 1184/1812 (65%), Positives = 1351/1812 (74%), Gaps = 44/1812 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVR GTAFPTDI+EPVAVVGIGCR PGNV+GPDSFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGNVTGPDSFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LVDG DA+ EVP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LVDGGDAISEVPPDRWDADAFYDPDPSASGRMTTKWGGFVPDVDAFDAEFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWE+LEHAG+ PDSLSGTRTA +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRMLLEVAWESLEHAGIAPDSLSGTRTAVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRISYLLGLRGPA+AVDTACSSSLVA+HLACQSLRLRESDVALAGGVQL+LSP Sbjct: 181 TPHCAAVGRISYLLGLRGPAMAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRLVDA+RD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 NQDGRSNGMTAPNA AQRDVI TAL+LAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNQDGRSNGMTAPNALAQRDVITTALRLADITPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG +G SCALGSVKTN+GHLEAAAG+ FIK LA+ H YIP N+HF++WNPAIDA Sbjct: 361 YG----RGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAYIPRNVHFTQWNPAIDA 416 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQPRSG---LSA 475 S+TRLFVPT+ A WPA G RR AVSSFGLSGTNAHVV+EQ G +SA Sbjct: 417 STTRLFVPTESAPWPAIPGPRRGAVSSFGLSGTNAHVVIEQAPDTTVPISAAVGRQYVSA 476 Query: 476 LVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXX 535 LVVSGKT RVA+ A+ LADW+ GPG PLADVA+TLN HR RH K Sbjct: 477 LVVSGKTVTRVASAAAVLADWMSGPGAAAPLADVAYTLNQHRVRHPKLATVIARDHADAV 536 Query: 536 EGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELE 595 GLRALAAGQP GV+GC PG VFVYSGQGSQW GMGRQLL DEP+FA A+AELE Sbjct: 537 AGLRALAAGQPRVGVVGCDQHAAGPGRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELE 596 Query: 596 PDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEV 655 P FVAQ GFSL+ TL G EVVGI+RIQPVLVGIQLALT LWRS+GVTPDAV+GHSMGEV Sbjct: 597 PTFVAQVGFSLEHTLAYGDEVVGIERIQPVLVGIQLALTELWRSYGVTPDAVIGHSMGEV 656 Query: 656 SAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHA 715 SAAVVAGALTP G +VIATRSRLMARL+GQG YP+VTLAV+A Sbjct: 657 SAAVVAGALTPEQGLRVIATRSRLMARLSGQGAMALLELDADAAEALIADYPEVTLAVYA 716 Query: 716 SPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQP 775 SP QSV+AG PESVDAVI+ VA QNRLARR++V+VASHH IIDPILP+LR+ALADL PQ Sbjct: 717 SPRQSVIAGLPESVDAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQT 776 Query: 776 PAIPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTA-------GAQHHTFVEISPHP 828 P IP+ITTT E Q V+DADYWAANLRNPVRFHQAI A H+F+EISPHP Sbjct: 777 PIIPIITTTHEHTQAVMDADYWAANLRNPVRFHQAIAQAVSGVGGFNRTCHSFIEISPHP 836 Query: 829 LLTHAITDTLAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTP 888 +LTHAITDT+ S ++T+ + RD D + FH LA VG +D+ G+L D+P TP Sbjct: 837 VLTHAITDTVGG--SGGHVVTSAMNRDLDQTLFFHAQLATVGVTESDSAKGRLVDLPPTP 894 Query: 889 WQHTQFWVEDRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAI 948 WQH++FWV DRS +SEL AHPLLGVH+E+P DH WQADVGT CPWL DHKVFGQ I Sbjct: 895 WQHSRFWVADRSAMSELAVAHPLLGVHVEMPGSGDHGWQADVGTDVCPWLADHKVFGQPI 954 Query: 949 MPXXXXXXXXXXXXXXXFDLPVDA----LSINQLEIEQMLDLDEHTQVTTQLTRRADDKT 1004 MP +P + I+Q E+EQML LD HT +TTQLT + K Sbjct: 955 MPAAAFAEIAVAAASEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKI 1014 Query: 1005 RIEIYSRSASG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNH 1063 R+EIYSRS G + RHA A E + +A ++ + + PAD YA+LRQ GQ+H Sbjct: 1015 RVEIYSRSPRGDFSRHATANVEHVSHNAVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHH 1074 Query: 1064 GPAFAALTRILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGS 1123 GP FA LTRI R DGS ETEITL DE PRH GYR+HP +LDAALQS+ AA+P+ E A S Sbjct: 1075 GPVFAVLTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQSVGAAIPDGEVAES 1134 Query: 1124 AEASYLPVSFETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIY 1183 AE SYLPVSFE +RVY + GRHA CRA+LTNL DGG GKLG+I L DDAG V E++ IY Sbjct: 1135 AEVSYLPVSFEAIRVYRDIGRHALCRARLTNL-DGGTGKLGKIVLIDDAGYVAAEVDGIY 1193 Query: 1184 LRRVERRSVPLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----AKSNADE 1234 LRR+ERR VPLPLAQKIFD EW+E I + + A SWLVLTD KS DE Sbjct: 1194 LRRIERRVVPLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDPSIKSLTDE 1253 Query: 1235 FVARWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRI 1294 F+ARW SP RRV TA+L DE GDPE P Sbjct: 1254 FIARWRSPMRRVYTANLHDESAMLAAFAETAGDPEHPPIGVVIFVGGAATGLD------- 1306 Query: 1295 SYDGLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVHD-EPGRPAIGALQGLV 1353 DGL+Q+RD+VW ISTVVRAIV TWHGR+PRLWL+ GGL V D E G PA AL+GLV Sbjct: 1307 --DGLVQARDSVWSISTVVRAIVSTWHGRSPRLWLIAGGGLSVQDDELGAPATAALKGLV 1364 Query: 1354 RVLAYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAI 1413 RVLA E+P+LRATL+DLD D + L EL + + DDV+AWR HR+V +LC+A Sbjct: 1365 RVLALENPDLRATLLDLDATQDQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKAT 1424 Query: 1414 LDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAE 1473 LD +PV+RPGA+YIVT VVARWLVD GAGRVVL RS+P++EQRK L E Sbjct: 1425 LDAGKD-NPVVRPGAAYIVTGGLGGLGLVVARWLVDRGAGRVVLGSRSDPTEEQRKTLVE 1483 Query: 1474 LESRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERV 1533 LE+RAE+V + GD + GVAESLVAAA QLRGIVHGAAVI+DSL+F+MT+++LERV Sbjct: 1484 LEARAEIVFLRGDVTSPGVAESLVAAAGRAGGQLRGIVHGAAVIEDSLVFTMTRENLERV 1543 Query: 1534 WAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGL 1593 WAPKA GALR+H A+ + ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WR+A+GL Sbjct: 1544 WAPKATGALRMHQASVSCELDWWLGFSSVASLLGSPGQAAYACASAWLDALVMWRKASGL 1603 Query: 1594 PAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIA 1653 P+A INWGPWS+VGVAQALVG+ LD ITPAEG+ R RTGVARLR+D+AL+A Sbjct: 1604 PSAVINWGPWSDVGVAQALVGSVLDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVA 1663 Query: 1654 FPEIRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYAD 1713 FPE+R++ YFT VV++L + L ++DPAEA++VVTER+ IAAVMGYAD Sbjct: 1664 FPEMRSISYFTWVVEQLAAAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYAD 1723 Query: 1714 RSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDLA 1773 RS V+ ++PLTELGLDSLMAVRIRN ARADFGVEPPVTLILQGASL DLT DV+RQL LA Sbjct: 1724 RSTVNPAVPLTELGLDSLMAVRIRNGARADFGVEPPVTLILQGASLQDLTADVVRQLGLA 1783 Query: 1774 GDEQTHEHVDVV 1785 G +Q E+ D V Sbjct: 1784 GPKQALENADTV 1795 >tr|B8ZT37|B8ZT37_MYCLB Tax_Id=561304 SubName: Full=Polyketide synthase;[Mycobacterium leprae] Length = 1822 Score = 2266 bits (5872), Expect = 0.0 Identities = 1184/1812 (65%), Positives = 1351/1812 (74%), Gaps = 44/1812 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVR GTAFPTDI+EPVAVVGIGCR PGNV+GPDSFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGNVTGPDSFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LVDG DA+ EVP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LVDGGDAISEVPPDRWDADAFYDPDPSASGRMTTKWGGFVPDVDAFDAEFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWE+LEHAG+ PDSLSGTRTA +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRMLLEVAWESLEHAGIAPDSLSGTRTAVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRISYLLGLRGPA+AVDTACSSSLVA+HLACQSLRLRESDVALAGGVQL+LSP Sbjct: 181 TPHCAAVGRISYLLGLRGPAMAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRLVDA+RD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 NQDGRSNGMTAPNA AQRDVI TAL+LAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNQDGRSNGMTAPNALAQRDVITTALRLADITPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG +G SCALGSVKTN+GHLEAAAG+ FIK LA+ H YIP N+HF++WNPAIDA Sbjct: 361 YG----RGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAYIPRNVHFTQWNPAIDA 416 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQPRSG---LSA 475 S+TRLFVPT+ A WPA G RR AVSSFGLSGTNAHVV+EQ G +SA Sbjct: 417 STTRLFVPTESAPWPAIPGPRRGAVSSFGLSGTNAHVVIEQAPDTTVPISAAVGRQYVSA 476 Query: 476 LVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXX 535 LVVSGKT RVA+ A+ LADW+ GPG PLADVA+TLN HR RH K Sbjct: 477 LVVSGKTVTRVASAAAVLADWMSGPGAAAPLADVAYTLNQHRVRHPKLATVIARDHADAV 536 Query: 536 EGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELE 595 GLRALAAGQP GV+GC PG VFVYSGQGSQW GMGRQLL DEP+FA A+AELE Sbjct: 537 AGLRALAAGQPRVGVVGCDQHAAGPGRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELE 596 Query: 596 PDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEV 655 P FVAQ GFSL+ TL G EVVGI+RIQPVLVGIQLALT LWRS+GVTPDAV+GHSMGEV Sbjct: 597 PTFVAQVGFSLEHTLAYGDEVVGIERIQPVLVGIQLALTELWRSYGVTPDAVIGHSMGEV 656 Query: 656 SAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHA 715 SAAVVAGALTP G +VIATRSRLMARL+GQG YP+VTLAV+A Sbjct: 657 SAAVVAGALTPEQGLRVIATRSRLMARLSGQGAMALLELDADAAEALIADYPEVTLAVYA 716 Query: 716 SPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQP 775 SP QSV+AG PESVDAVI+ VA QNRLARR++V+VASHH IIDPILP+LR+ALADL PQ Sbjct: 717 SPRQSVIAGLPESVDAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQT 776 Query: 776 PAIPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTA-------GAQHHTFVEISPHP 828 P IP+ITTT E Q V+DADYWAANLRNPVRFHQAI A H+F+EISPHP Sbjct: 777 PIIPIITTTHEHTQAVMDADYWAANLRNPVRFHQAIAQAVSGVGGFNRTCHSFIEISPHP 836 Query: 829 LLTHAITDTLAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTP 888 +LTHAITDT+ S ++T+ + RD D + FH LA VG +D+ G+L D+P TP Sbjct: 837 VLTHAITDTVGG--SGGHVVTSAMNRDLDQTLFFHAQLATVGVTESDSAKGRLVDLPPTP 894 Query: 889 WQHTQFWVEDRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAI 948 WQH++FWV DRS +SEL AHPLLGVH+E+P DH WQADVGT CPWL DHKVFGQ I Sbjct: 895 WQHSRFWVADRSAMSELAVAHPLLGVHVEMPGSGDHGWQADVGTDVCPWLADHKVFGQPI 954 Query: 949 MPXXXXXXXXXXXXXXXFDLPVDA----LSINQLEIEQMLDLDEHTQVTTQLTRRADDKT 1004 MP +P + I+Q E+EQML LD HT +TTQLT + K Sbjct: 955 MPAAAFAEIAVAAASEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKI 1014 Query: 1005 RIEIYSRSASG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNH 1063 R+EIYSRS G + RHA A E + +A ++ + + PAD YA+LRQ GQ+H Sbjct: 1015 RVEIYSRSPRGDFSRHATANVEHVSHNAVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHH 1074 Query: 1064 GPAFAALTRILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGS 1123 GP FA LTRI R DGS ETEITL DE PRH GYR+HP +LDAALQS+ AA+P+ E A S Sbjct: 1075 GPVFAVLTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQSVGAAIPDGEVAES 1134 Query: 1124 AEASYLPVSFETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIY 1183 AE SYLPVSFE +RVY + GRHA CRA+LTNL DGG GKLG+I L DDAG V E++ IY Sbjct: 1135 AEVSYLPVSFEAIRVYRDIGRHALCRARLTNL-DGGTGKLGKIVLIDDAGYVAAEVDGIY 1193 Query: 1184 LRRVERRSVPLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----AKSNADE 1234 LRR+ERR VPLPLAQKIFD EW+E I + + A SWLVLTD KS DE Sbjct: 1194 LRRIERRVVPLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDPSIKSLTDE 1253 Query: 1235 FVARWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRI 1294 F+ARW SP RRV TA+L DE GDPE P Sbjct: 1254 FIARWRSPMRRVYTANLHDESAMLAAFAETAGDPEHPPIGVVIFVGGAATGLD------- 1306 Query: 1295 SYDGLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVHD-EPGRPAIGALQGLV 1353 DGL+Q+RD+VW ISTVVRAIV TWHGR+PRLWL+ GGL V D E G PA AL+GLV Sbjct: 1307 --DGLVQARDSVWSISTVVRAIVSTWHGRSPRLWLIAGGGLSVQDDELGAPATAALKGLV 1364 Query: 1354 RVLAYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAI 1413 RVLA E+P+LRATL+DLD D + L EL + + DDV+AWR HR+V +LC+A Sbjct: 1365 RVLALENPDLRATLLDLDATQDQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKAT 1424 Query: 1414 LDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAE 1473 LD +PV+RPGA+YIVT VVARWLVD GAGRVVL RS+P++EQRK L E Sbjct: 1425 LDAGKD-NPVVRPGAAYIVTGGLGGLGLVVARWLVDRGAGRVVLGSRSDPTEEQRKTLVE 1483 Query: 1474 LESRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERV 1533 LE+RAE+V + GD + GVAESLVAAA QLRGIVHGAAVI+DSL+F+MT+++LERV Sbjct: 1484 LEARAEIVFLRGDVTSPGVAESLVAAAGRAGGQLRGIVHGAAVIEDSLVFTMTRENLERV 1543 Query: 1534 WAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGL 1593 WAPKA GALR+H A+ + ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WR+A+GL Sbjct: 1544 WAPKATGALRMHQASVSCELDWWLGFSSVASLLGSPGQAAYACASAWLDALVMWRKASGL 1603 Query: 1594 PAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIA 1653 P+A INWGPWS+VGVAQALVG+ LD ITPAEG+ R RTGVARLR+D+AL+A Sbjct: 1604 PSAVINWGPWSDVGVAQALVGSVLDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVA 1663 Query: 1654 FPEIRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYAD 1713 FPE+R++ YFT VV++L + L ++DPAEA++VVTER+ IAAVMGYAD Sbjct: 1664 FPEMRSISYFTWVVEQLAAAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYAD 1723 Query: 1714 RSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDLA 1773 RS V+ ++PLTELGLDSLMAVRIRN ARADFGVEPPVTLILQGASL DLT DV+RQL LA Sbjct: 1724 RSTVNPAVPLTELGLDSLMAVRIRNGARADFGVEPPVTLILQGASLQDLTADVVRQLGLA 1783 Query: 1774 GDEQTHEHVDVV 1785 G +Q E+ D V Sbjct: 1784 GPKQALENADTV 1795 >tr|Q49940|Q49940_MYCLE Tax_Id=1769 SubName: Full=PksE;[Mycobacterium leprae] Length = 1815 Score = 2266 bits (5872), Expect = 0.0 Identities = 1184/1812 (65%), Positives = 1351/1812 (74%), Gaps = 44/1812 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVR GTAFPTDI+EPVAVVGIGCR PGNV+GPDSFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRTGTAFPTDISEPVAVVGIGCRFPGNVTGPDSFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LVDG DA+ EVP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LVDGGDAISEVPPDRWDADAFYDPDPSASGRMTTKWGGFVPDVDAFDAEFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWE+LEHAG+ PDSLSGTRTA +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRMLLEVAWESLEHAGIAPDSLSGTRTAVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRISYLLGLRGPA+AVDTACSSSLVA+HLACQSLRLRESDVALAGGVQL+LSP Sbjct: 181 TPHCAAVGRISYLLGLRGPAMAVDTACSSSLVAIHLACQSLRLRESDVALAGGVQLILSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRLVDA+RD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLVDALRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 NQDGRSNGMTAPNA AQRDVI TAL+LAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNQDGRSNGMTAPNALAQRDVITTALRLADITPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG +G SCALGSVKTN+GHLEAAAG+ FIK LA+ H YIP N+HF++WNPAIDA Sbjct: 361 YG----RGESSCALGSVKTNIGHLEAAAGVAGFIKTVLALQHAYIPRNVHFTQWNPAIDA 416 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQPRSG---LSA 475 S+TRLFVPT+ A WPA G RR AVSSFGLSGTNAHVV+EQ G +SA Sbjct: 417 STTRLFVPTESAPWPAIPGPRRGAVSSFGLSGTNAHVVIEQAPDTTVPISAAVGRQYVSA 476 Query: 476 LVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXX 535 LVVSGKT RVA+ A+ LADW+ GPG PLADVA+TLN HR RH K Sbjct: 477 LVVSGKTVTRVASAAAVLADWMSGPGAAAPLADVAYTLNQHRVRHPKLATVIARDHADAV 536 Query: 536 EGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELE 595 GLRALAAGQP GV+GC PG VFVYSGQGSQW GMGRQLL DEP+FA A+AELE Sbjct: 537 AGLRALAAGQPRVGVVGCDQHAAGPGRVFVYSGQGSQWAGMGRQLLVDEPAFAKAVAELE 596 Query: 596 PDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEV 655 P FVAQ GFSL+ TL G EVVGI+RIQPVLVGIQLALT LWRS+GVTPDAV+GHSMGEV Sbjct: 597 PTFVAQVGFSLEHTLAYGDEVVGIERIQPVLVGIQLALTELWRSYGVTPDAVIGHSMGEV 656 Query: 656 SAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHA 715 SAAVVAGALTP G +VIATRSRLMARL+GQG YP+VTLAV+A Sbjct: 657 SAAVVAGALTPEQGLRVIATRSRLMARLSGQGAMALLELDADAAEALIADYPEVTLAVYA 716 Query: 716 SPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQP 775 SP QSV+AG PESVDAVI+ VA QNRLARR++V+VASHH IIDPILP+LR+ALADL PQ Sbjct: 717 SPRQSVIAGLPESVDAVISVVAEQNRLARRVDVEVASHHSIIDPILPELRNALADLVPQT 776 Query: 776 PAIPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTA-------GAQHHTFVEISPHP 828 P IP+ITTT E Q V+DADYWAANLRNPVRFHQAI A H+F+EISPHP Sbjct: 777 PIIPIITTTHEHTQAVMDADYWAANLRNPVRFHQAIAQAVSGVGGFNRTCHSFIEISPHP 836 Query: 829 LLTHAITDTLAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTP 888 +LTHAITDT+ S ++T+ + RD D + FH LA VG +D+ G+L D+P TP Sbjct: 837 VLTHAITDTVGG--SGGHVVTSAMNRDLDQTLFFHAQLATVGVTESDSAKGRLVDLPPTP 894 Query: 889 WQHTQFWVEDRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAI 948 WQH++FWV DRS +SEL AHPLLGVH+E+P DH WQADVGT CPWL DHKVFGQ I Sbjct: 895 WQHSRFWVADRSAMSELAVAHPLLGVHVEMPGSGDHGWQADVGTDVCPWLADHKVFGQPI 954 Query: 949 MPXXXXXXXXXXXXXXXFDLPVDA----LSINQLEIEQMLDLDEHTQVTTQLTRRADDKT 1004 MP +P + I+Q E+EQML LD HT +TTQLT + K Sbjct: 955 MPAAAFAEIAVAAADEALGVPAGTSGANIVIHQFEVEQMLSLDNHTPLTTQLTYHGNSKI 1014 Query: 1005 RIEIYSRSASG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNH 1063 R+EIYSRS G + RHA A E + +A ++ + + PAD YA+LRQ GQ+H Sbjct: 1015 RVEIYSRSPRGDFSRHATANVEHVSHNAVQPFQQAPGSSNGVTVSPADFYAVLRQTGQHH 1074 Query: 1064 GPAFAALTRILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGS 1123 GP FA LTRI R DGS ETEITL DE PRH GYR+HP +LDAALQS+ AA+P+ E A S Sbjct: 1075 GPVFAVLTRITRLLDGSAETEITLPDEVPRHPGYRLHPVVLDAALQSVGAAIPDGEVAES 1134 Query: 1124 AEASYLPVSFETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIY 1183 AE SYLPVSFE +RVY + GRHA CRA+LTNL DGG GKLG+I L DDAG V E++ IY Sbjct: 1135 AEVSYLPVSFEAIRVYRDIGRHALCRARLTNL-DGGTGKLGKIVLIDDAGYVAAEVDGIY 1193 Query: 1184 LRRVERRSVPLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----AKSNADE 1234 LRR+ERR VPLPLAQKIFD EW+E I + + A SWLVLTD KS DE Sbjct: 1194 LRRIERRVVPLPLAQKIFDAEWIESPIPASRALEQITETARASWLVLTDWDPSIKSLTDE 1253 Query: 1235 FVARWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRI 1294 F+ARW SP RRV TA+L DE GDPE P Sbjct: 1254 FIARWRSPMRRVYTANLHDESAMLAAFAETAGDPEHPPIGVVIFVGGAATGLD------- 1306 Query: 1295 SYDGLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVHD-EPGRPAIGALQGLV 1353 DGL+Q+RD+VW ISTVVRAIV TWHGR+PRLWL+ GGL V D E G PA AL+GLV Sbjct: 1307 --DGLVQARDSVWSISTVVRAIVSTWHGRSPRLWLIAGGGLSVQDDELGAPATAALKGLV 1364 Query: 1354 RVLAYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAI 1413 RVLA E+P+LRATL+DLD D + L EL + + DDV+AWR HR+V +LC+A Sbjct: 1365 RVLALENPDLRATLLDLDATQDQIAALTAELHNSASEFGGDDVIAWRGQHRFVERLCKAT 1424 Query: 1414 LDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAE 1473 LD +PV+RPGA+YIVT VVARWLVD GAGRVVL RS+P++EQRK L E Sbjct: 1425 LDAGKD-NPVVRPGAAYIVTGGLGGLGLVVARWLVDRGAGRVVLGSRSDPTEEQRKTLVE 1483 Query: 1474 LESRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERV 1533 LE+RAE+V + GD + GVAESLVAAA QLRGIVHGAAVI+DSL+F+MT+++LERV Sbjct: 1484 LEARAEIVFLRGDVTSPGVAESLVAAAGRAGGQLRGIVHGAAVIEDSLVFTMTRENLERV 1543 Query: 1534 WAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGL 1593 WAPKA GALR+H A+ + ELDWWLGFSS ASLLGSPGQ AYACASAWLD LV WR+A+GL Sbjct: 1544 WAPKATGALRMHQASVSCELDWWLGFSSVASLLGSPGQAAYACASAWLDALVMWRKASGL 1603 Query: 1594 PAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIA 1653 P+A INWGPWS+VGVAQALVG+ LD ITPAEG+ R RTGVARLR+D+AL+A Sbjct: 1604 PSAVINWGPWSDVGVAQALVGSVLDTITPAEGIEAIDSLLAAGRTRTGVARLRADKALVA 1663 Query: 1654 FPEIRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYAD 1713 FPE+R++ YFT VV++L + L ++DPAEA++VVTER+ IAAVMGYAD Sbjct: 1664 FPEMRSISYFTWVVEQLAAAGDLGDWVGSDTLADLDPAEAQRVVTERMCALIAAVMGYAD 1723 Query: 1714 RSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDLA 1773 RS V+ ++PLTELGLDSLMAVRIRN ARADFGVEPPVTLILQGASL DLT DV+RQL LA Sbjct: 1724 RSTVNPAVPLTELGLDSLMAVRIRNGARADFGVEPPVTLILQGASLQDLTADVVRQLGLA 1783 Query: 1774 GDEQTHEHVDVV 1785 G +Q E+ D V Sbjct: 1784 GPKQALENADTV 1795 >tr|A1T9S6|A1T9S6_MYCVP Tax_Id=350058 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium vanbaalenii] Length = 1805 Score = 1878 bits (4864), Expect = 0.0 Identities = 999/1794 (55%), Positives = 1224/1794 (68%), Gaps = 39/1794 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + +R + MS + R LA + +A AEP+AVVGIGCRLPG V+GPDS+W+L Sbjct: 1 MKTTFDRISAMSAEQRGKLAEQFEKASRVAG---AEPIAVVGIGCRLPGGVTGPDSYWEL 57 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L +G DA+ EVPADRWD DAFYDPDP APGRM TKW TPREA A Sbjct: 58 LENGTDAITEVPADRWDGDAFYDPDPMAPGRMPTKWGAYLDDVSGFDADFFGITPREAAA 117 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQRVLLEVAWEALE+AGL PD+LS TRTA +MG+ +Y + IDAY +TG Sbjct: 118 MDPQQRVLLEVAWEALENAGLAPDTLSETRTAVMMGVYYTEYQNSSAGNPDTIDAYSATG 177 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRI+YLLGL+GPAVAVDTACSSSLV++HLAC SLR+RESD+ALAGGV L L P Sbjct: 178 NAHSVTVGRIAYLLGLKGPAVAVDTACSSSLVSIHLACHSLRMRESDLALAGGVSLNLRP 237 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T +AL+KW LSP G+C FD+ ADGFVR EG GVVVLKRL DAVRDGDRVL VVRGSA Sbjct: 238 ETQLALAKWGMLSPHGKCFAFDSRADGFVRGEGAGVVVLKRLTDAVRDGDRVLGVVRGSA 297 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPNA +QRDVI AL+ AD A +V+Y+ETHGTGT LGDPIEF+ALAA Sbjct: 298 VNQDGRSNGLTAPNAPSQRDVITRALRSADVAAGTVDYIETHGTGTGLGDPIEFDALAAV 357 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG KG CALG+VKTN+GHLEAAAG+ FIK L++ HG I PNL+F +WNP ID Sbjct: 358 YG----KGEVPCALGAVKTNMGHLEAAAGVAGFIKTVLSLQHGKIAPNLNFEKWNPQIDP 413 Query: 421 SSTRLFVPTQGAQWPAGL--RRAAVSSFGLSGTNAHVVLEQXXXXXXXDQPRSGLSALVV 478 TRLFVPT+ WP RRAAVSSFG+ GTNAH+VLEQ +G+ LVV Sbjct: 414 KPTRLFVPTEAQDWPKSEHPRRAAVSSFGMGGTNAHIVLEQGPEPAPAGAADTGVVTLVV 473 Query: 479 SGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGL 538 SGKT +R+AA A +LADW+DG G PL DVA+T+NHHR+R+ GL Sbjct: 474 SGKTSERLAASARSLADWLDGDGADVPLVDVAYTVNHHRSRYQTIATVCARTHAEAVTGL 533 Query: 539 RALAAGQPGPGVLGCQDVQNQ----PGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAEL 594 RALA G+P PGV+ D + G VF+YSGQG+QW GMG+ LL EP+FAAA+ EL Sbjct: 534 RALADGRPAPGVIAPHDAKGGVAAGKGVVFLYSGQGAQWAGMGKTLLTSEPAFAAAVDEL 593 Query: 595 EPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGE 654 EP FV + GFSL+QTL G VVGIDRIQPVLVG+QLALTALWRS+GV PDAV+GHSMGE Sbjct: 594 EPAFVEKVGFSLRQTLEAGEPVVGIDRIQPVLVGMQLALTALWRSYGVEPDAVIGHSMGE 653 Query: 655 VSAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVH 714 +AAVVAG LTPA+GF VIATR+RLM RL+GQG VT+AV+ Sbjct: 654 ATAAVVAGVLTPAEGFDVIATRTRLMKRLSGQGAMALLELDAQATEKLIADRSDVTIAVY 713 Query: 715 ASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQ 774 ASP Q+V+AGPPE VD ++AAV Q +LARRIEVDVASHHP IDP+LP+LR ALA LTP Sbjct: 714 ASPKQTVIAGPPEQVDELVAAVDAQGKLARRIEVDVASHHPTIDPVLPELREALAYLTPA 773 Query: 775 PPAIPMITTT-CEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHA 833 P IP+++T P+ ADYWAANLRNPVRF QA+ A A++ F+EISPHPLLTHA Sbjct: 774 APKIPLVSTVGYAGDAPMYSADYWAANLRNPVRFSQAVHDASAENSNFIEISPHPLLTHA 833 Query: 834 ITDTLAA-AESRTRLITATLQRDGDDAITFHTNLAAVGKKPA----DAVTGQLADIPVTP 888 I+DTLAA + SR + AT+ RD + + FH LAAV + PA + G+LADIP T Sbjct: 834 ISDTLAAQSTSRRYHVGATVNRDNPEPLAFHAQLAAV-RPPAVQAPEGTPGRLADIPPTA 892 Query: 889 WQHTQFWVEDRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAI 948 WQH+ +W+ DRS AHPLLG+H+E+PSG HVWQ+DVG +A PWL DH V G A+ Sbjct: 893 WQHSPYWMVDRSAGQGFSGAHPLLGLHVELPSGTGHVWQSDVGVQAHPWLADHIVHGLAV 952 Query: 949 MPXXXXXXXXXXXXXXXFDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEI 1008 MP LP + + QLE+EQML LD+HT++TTQLTR ++ R+EI Sbjct: 953 MPGAGFAEIALAAGREALGLPATGVEV-QLEVEQMLPLDDHTKLTTQLTRDDEENLRVEI 1011 Query: 1009 YSRSASG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAF 1067 +SRS +G W RHAV T +A P + D T + P+D Y LR+ G +H AF Sbjct: 1012 HSRSDAGSWTRHAVG---TVKAAAGPAPAKVVPASDGTPVSPSDFYTALRRTGAHHAHAF 1068 Query: 1068 AALTRILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEAS 1127 AALTRI+R G +TEI L DEA H+G +HP MLDAALQ LAAA+ ++ + S + + Sbjct: 1069 AALTRIVRA-GGRADTEIVLPDEATPHRGIALHPVMLDAALQGLAAAMSDETLSDSTDVT 1127 Query: 1128 YLPVSFETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRV 1187 YLPV F ++RV+ + GR A+CRA+L ++ + +GR+TLTDD G V +++D++L+RV Sbjct: 1128 YLPVGFGSIRVFGDIGRRAKCRAELVSVVEDSGDAMGRVTLTDDTGTVLAQVDDVHLKRV 1187 Query: 1188 ERRSVPLPLAQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSN---ADEFVARWSSPQR 1244 +RR+VPLPL+QKIFD+ WVE + A A GSWL L D + A +F +R+ + R Sbjct: 1188 QRRTVPLPLSQKIFDSRWVESAAAAGTT--ATGSWLALADGAAGQAAAQDFASRFGADTR 1245 Query: 1245 RVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRD 1304 RVITADLGDE DP+ LP ++ GL +RD Sbjct: 1246 RVITADLGDESAVREAFATATADPD-LPPVGVVVFCDFGGNPATLDGTDVA-GGLEHARD 1303 Query: 1305 TVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVHDEPGR--PAIGALQGLVRVLAYEHPE 1362 +W ++ VRAIVG+WHG+APRLWLVT+GGLVV E G+ P +L+GL RVLAYEHP+ Sbjct: 1304 VIWGVAGTVRAIVGSWHGKAPRLWLVTQGGLVVSPEDGQGNPGANSLKGLARVLAYEHPD 1363 Query: 1363 LRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDP 1422 L+ TL LDTG+D LA E+ + +DV+AWR G RYV +L RA L P + Sbjct: 1364 LKTTL--LDTGSDGAA-LATEIEAASASAVTEDVIAWRGGTRYVERLSRATLPATPGQLV 1420 Query: 1423 VIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVV 1482 V R GA Y+VT V RWLVD GAGR+VLNGRS PSDE L L RAE+ V Sbjct: 1421 VRRDGA-YVVTGALGGVGMAVVRWLVDHGAGRLVLNGRSGPSDEVAAELDTLSHRAEIAV 1479 Query: 1483 VCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGAL 1542 V GD A GVAE LVAAAE+ + LRG++H AAV++D + MT++SL+++WAPKAAGAL Sbjct: 1480 VTGDVAEPGVAERLVAAAEETGKPLRGLIHSAAVLEDEIFVGMTRESLDKIWAPKAAGAL 1539 Query: 1543 RLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGP 1602 RLH+ TA +LDWW+GFSS SLLGSPGQ AYACA+AWLDGLVAWR AAGLPA +NWG Sbjct: 1540 RLHEVTAGSDLDWWVGFSSIVSLLGSPGQAAYACANAWLDGLVAWRTAAGLPALAVNWGQ 1599 Query: 1603 WSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGY 1662 W++VG+A L + LDPITPAEGV R G+ARLR DRA AFPEI+ +G+ Sbjct: 1600 WADVGLASTLRFSVLDPITPAEGVEALGGVMAAGFSRVGIARLRLDRAAAAFPEIQQIGF 1659 Query: 1663 FTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMP 1722 F +V EL EALK MD AE +VV RL RI+A+MGY+D +AVD + P Sbjct: 1660 FADLVGELETDDVDEDWGGVEALKSMDAAEVNRVVVARLRRRISAIMGYSDDNAVDTAQP 1719 Query: 1723 LTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDLAGDE 1776 LTELGLDSLMAVR+RNT R DFGVEPPV L+LQGA+L DL +D+IRQL L E Sbjct: 1720 LTELGLDSLMAVRMRNTIRGDFGVEPPVALLLQGATLADLALDLIRQLGLEEQE 1773 >tr|A4TA92|A4TA92_MYCGI Tax_Id=350054 SubName: Full=Beta-ketoacyl synthase;[Mycobacterium gilvum] Length = 1806 Score = 1838 bits (4760), Expect = 0.0 Identities = 970/1797 (53%), Positives = 1212/1797 (67%), Gaps = 44/1797 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + +R + MS + R+ LA + +A AEP+AVVG+GCR PG + PDS+W++ Sbjct: 1 MKTTFDRISAMSAEQRDKLAEQFEKASRVAG---AEPIAVVGMGCRFPGGATDPDSYWKV 57 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L G +AV EVPADRWD DA+YDPDP APGRM +KW TPREA A Sbjct: 58 LESGTNAVTEVPADRWDGDAYYDPDPMAPGRMPSKWGAYIDDMAGFDAEFFGITPREAAA 117 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR++LEVA+EALE+AGL PD++ R A ++G+ +Y + IDAY +TG Sbjct: 118 MDPQQRIVLEVAYEALENAGLAPDTVGDIRGAVMLGVYYNEYQSASAGNPDTIDAYSATG 177 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRI+YLLGL+GPAVAVDTACSSSLV++HLACQSLR+RESD+ALAGGV L L P Sbjct: 178 NAHSVTVGRIAYLLGLKGPAVAVDTACSSSLVSIHLACQSLRMRESDLALAGGVSLSLRP 237 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T +AL KW LSP G+C FD+ ADGFVR EG GVVVLKRL DAVRDGDRVL VVRGSA Sbjct: 238 ETQLALGKWGMLSPHGKCYAFDSRADGFVRGEGAGVVVLKRLTDAVRDGDRVLGVVRGSA 297 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPNA +QRDVI AL+ AD A +VN+VETHGTGT LGDPIEF+AL+A Sbjct: 298 VNQDGRSNGLTAPNAPSQRDVITRALRSADVAAGTVNFVETHGTGTSLGDPIEFDALSAV 357 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG KG CALG+VKTN+GH+EAAAGI FIKA L + HG I PNLHF +WNP+I+A Sbjct: 358 YG----KGDTPCALGAVKTNMGHMEAAAGIGGFIKAVLTLQHGAIAPNLHFQKWNPSINA 413 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXD-QPRSGLSALV 477 + TRLFVPT+ WP RRAAVSSFG+ GTNAH+VLEQ P ++ LV Sbjct: 414 TGTRLFVPTEKTDWPETDHPRRAAVSSFGMGGTNAHIVLEQGPDVAAAPVDPAPKVATLV 473 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKTPQR+AA A++LADW+DG G Q PL DVAHT+NHHR+R G Sbjct: 474 VSGKTPQRLAAAAASLADWLDGDGAQVPLTDVAHTVNHHRSRFPTIATVCARTHAEAVAG 533 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQ PGV+G + ++ GTVF+YSGQG+QW GMGR LLADEP+FAAA+ ELEP Sbjct: 534 LRALAAGQTAPGVVGARAAKSGTGTVFLYSGQGAQWAGMGRTLLADEPAFAAAVDELEPA 593 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV + GFSL+QTL G V GIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGE +A Sbjct: 594 FVDKVGFSLRQTLEAGEPVTGIDRIQPVLVGMQLALTQLWRSYGVEPDAVIGHSMGEATA 653 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAG LTPA+GF +IATR+RLM RL+GQG P +T+AV+ASP Sbjct: 654 AVVAGVLTPAEGFDIIATRTRLMKRLSGQGAMALLELDAQATEKLIADRPDITIAVYASP 713 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q V+AGPPE VD ++A V Q +LARR+EVDVASHHP IDP+L +LR AL+ L+P P Sbjct: 714 KQCVIAGPPEQVDELVALVDAQGKLARRVEVDVASHHPTIDPVLGELRDALSYLSPAAPK 773 Query: 778 IPMITTTC-EQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITD 836 IP+++T P+ ADYWAANLRNPVRF QA+ A A H FVEISPHPLLTHAI+D Sbjct: 774 IPLVSTVAYAGSAPLYSADYWAANLRNPVRFSQAVHEAAADHSNFVEISPHPLLTHAISD 833 Query: 837 TLAA-AESRTRLITATLQRDGDDAITFHTNLAAVGKKPA----DAVTGQLADIPVTPWQH 891 TLAA + SR + ATL RD + + FH L+A+ + PA D TG++ D+P T WQH Sbjct: 834 TLAAQSTSRKFHVGATLNRDHPEPLAFHAQLSAL-RPPAVTAPDGATGRVVDVPATAWQH 892 Query: 892 TQFWVEDRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPX 951 T +W+ DRSG + AHPLLG+H+E+P+G HVWQ+DVG +A PWL DH V G +MP Sbjct: 893 TPYWMADRSGGPQFAGAHPLLGLHVELPAGAGHVWQSDVGLEAHPWLADHIVHGLPVMPG 952 Query: 952 XXXXXXXXXXXXXXFDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSR 1011 LP + + LE+++ML LD HT +TTQ++ D R+EI+SR Sbjct: 953 AGFAEIALAAAQEALGLPATGVEV-ALEVQEMLLLDAHTTLTTQVSTAEDGTLRVEIHSR 1011 Query: 1012 SASG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAAL 1070 S +G W RHA + + P + T + PAD Y LR+ G +H AFAAL Sbjct: 1012 SEAGTWTRHAAGSVRAAAGATPP---RPAPLSEGTPVSPADFYTALRRTGAHHAHAFAAL 1068 Query: 1071 TRILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLP 1130 TRI+R G+ +TEI L DEA H+G +HP MLDAALQ LAAA+ +D S + +YLP Sbjct: 1069 TRIVRAA-GTADTEIVLPDEATPHRGVALHPVMLDAALQGLAAALGDDSLTDSNDVTYLP 1127 Query: 1131 VSFETLRVYSNPGRHARCRAQLTNLNDGGAGK-----LGRITLTDDAGNVTVEINDIYLR 1185 V F ++RV++ GR A+CRA+L ++ G G+ +GR+TLTDD G V +++D+ L+ Sbjct: 1128 VGFGSVRVFAEVGRRAKCRAELLSVASGVDGQGSGDAVGRVTLTDDTGTVLAQVDDVALK 1187 Query: 1186 RVERRSVPLPLAQKIFDTEWV-EKSIAGADQPDAPGSWLVLTDAK---SNADEFVARWSS 1241 R++RR+VPLPL+QKIFD+ WV ++ AGA Q GSWLVL D ++A+ F + Sbjct: 1188 RIQRRTVPLPLSQKIFDSRWVPAQATAGAAQ---AGSWLVLADGDHTLASAERFAQSFGD 1244 Query: 1242 PQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQ 1301 Q RV+TA LGDE D P + GL Sbjct: 1245 AQHRVVTARLGDEAAVRDAFASATTDAALPPAGVVVLVDVPAFDGAD------AAGGLAA 1298 Query: 1302 SRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVV--HDEPGRPAIGALQGLVRVLAYE 1359 +++ VW+I+ VR IVG+WHG PRLW+V+ GGL V D G P +G L+ L+RVLAYE Sbjct: 1299 AQNAVWEIAETVRTIVGSWHGTPPRLWVVSRGGLAVTDGDNGGNPGVGTLKALIRVLAYE 1358 Query: 1360 HPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQ 1419 HP+LRATL+D+ D+ LA E+ S D +D +AWRDG R V +L RA L P Sbjct: 1359 HPDLRATLLDVGADGDTAAILATEIGSANDSTTTEDTIAWRDGSRLVERLSRAELPAVPG 1418 Query: 1420 RDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAE 1479 R V R SY+VT V RWLVD GAGR+VLNGRS PS E + V+ EL +RAE Sbjct: 1419 RLQV-RGDGSYVVTGALGGVGLAVVRWLVDHGAGRLVLNGRSGPSPEAQAVIDELSARAE 1477 Query: 1480 VVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAA 1539 + VV GD A G A L+AAAE+ R LRG++H AAV+DD L+ +T++S+E++WAPKAA Sbjct: 1478 IAVVTGDIAVPGTAVRLIAAAEETGRPLRGVLHSAAVLDDELVVGLTRESMEKIWAPKAA 1537 Query: 1540 GALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATIN 1599 GA RLH+ATA +ELDWW+ FSS ASLLGSPGQ+AYACA+AWLD LV WR AAGLPA T+N Sbjct: 1538 GAWRLHEATAGKELDWWVAFSSVASLLGSPGQSAYACANAWLDALVTWRAAAGLPATTVN 1597 Query: 1600 WGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRN 1659 WG W++VG+A +L + LDPITP EGV R G+ARLR DRA AFPEI+ Sbjct: 1598 WGQWADVGLASSLRFSVLDPITPDEGVEALGGVMAAGLTRVGIARLRLDRAAAAFPEIQQ 1657 Query: 1660 LGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDA 1719 +G+F +V EL EALK M AE +VV RL RIA VMGY++ SAVD Sbjct: 1658 IGFFADLVSELDTDDADDDWEGAEALKTMSAAEINRVVVARLRRRIAGVMGYSNDSAVDT 1717 Query: 1720 SMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQLDLAGDE 1776 + PLTE+GLDSLMAVR+RNT R DFGVEPPV L+LQGA+L+D+ +D+IRQL LA ++ Sbjct: 1718 AKPLTEMGLDSLMAVRMRNTIRGDFGVEPPVALLLQGATLNDVALDLIRQLGLAEED 1774 >tr|C6DWC0|C6DWC0_MYCTK Tax_Id=478434 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsD;[Mycobacterium tuberculosis] Length = 1405 Score = 1700 bits (4403), Expect = 0.0 Identities = 875/1277 (68%), Positives = 977/1277 (76%), Gaps = 26/1277 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 MTSLAERAAQ+SP AR LARELVRAGT FPTDI EPVAVVGIGCR PGNV+GP+SFWQL Sbjct: 1 MTSLAERAAQLSPNARAALARELVRAGTTFPTDICEPVAVVGIGCRFPGNVTGPESFWQL 60 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L DG D +++VP DRWDADAFYDPDP A GRMTTKW TPREAVA Sbjct: 61 LADGVDTIEQVPPDRWDADAFYDPDPSASGRMTTKWGGFVSDVDAFDADFFGITPREAVA 120 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQ R+LLEVAWEALEHAG+PPDSLSGTRT +MGLS+WDYTIVN+ERRA+IDAY+STG Sbjct: 121 MDPQHRMLLEVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRADIDAYLSTG 180 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 PH AAVGRI+YLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+DVALAGGVQL LSP Sbjct: 181 TPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRETDVALAGGVQLTLSP 240 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 FT+IALSKWSALSPTGRC +FDA ADGFVR EGCGVVVLKRL DAVRD DRVLAVVRGSA Sbjct: 241 FTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGVVVLKRLADAVRDQDRVLAVVRGSA 300 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 N DGRSNGMTAPNA AQRDVI +ALKLAD T DSVNYVETHGTGTVLGDPIEFE+LAAT Sbjct: 301 TNSDGRSNGMTAPNALAQRDVITSALKLADVTPDSVNYVETHGTGTVLGDPIEFESLAAT 360 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGLGK +G CALGSVKTN+GHLEAAAG+ FIKA LAV G+IP NLHF+RWNPAIDA Sbjct: 361 YGLGKGQGESPCALGSVKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDA 420 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ-PRSGLSALV 477 S+TRLFVPT+ A WP AG RRAAVSSFGLSGTNAHVV+EQ +SAL Sbjct: 421 SATRLFVPTESAPWPAAAGPRRAAVSSFGLSGTNAHVVVEQAPDTAVAAAGGMPYVSALN 480 Query: 478 VSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEG 537 VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HRARH KF G Sbjct: 481 VSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHRARHAKFATVIARDRAEAIAG 540 Query: 538 LRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPD 597 LRALAAGQP GV+ C PG VFVYSGQGSQW MG+QLLA+EP+FA A+AEL+P Sbjct: 541 LRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPI 600 Query: 598 FVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSA 657 FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LWRS+GV PDAV+GHSMGEVSA Sbjct: 601 FVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVIGHSMGEVSA 660 Query: 658 AVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASP 717 AVVAGALTP G +VI TRSRLMARL+GQG YPQVTLAVHASP Sbjct: 661 AVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADAAEALIAGYPQVTLAVHASP 720 Query: 718 HQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPA 777 Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPIIDPILP+LRSALADLTPQPP+ Sbjct: 721 RQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPIIDPILPELRSALADLTPQPPS 780 Query: 778 IPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDT 837 IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG H+TF+EISPHP+LTHA+TDT Sbjct: 781 IPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVDHNTFIEISPHPVLTHALTDT 840 Query: 838 LAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAVTGQLADIPVTPWQHTQFWVE 897 L S T + +T+ R+ D + FH LAAVG ++ TG+L D+P TPW H +FWV Sbjct: 841 LDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHTTGRLVDLPPTPWHHQRFWVT 898 Query: 898 DRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXX 957 DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPWL DHKVFGQ IMP Sbjct: 899 DRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEI 958 Query: 958 XXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA 1013 DA++ INQ E+EQML LD HT +TTQL R D + R+EIYSR+ Sbjct: 959 ALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSRTR 1018 Query: 1014 SG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTR 1072 G + RHA AK E S A E T + PAD YALLRQ GQ+HGPAFAAL+R Sbjct: 1019 GGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADFYALLRQTGQHHGPAFAALSR 1078 Query: 1073 ILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVS 1132 I+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ AA+P+ E AGSAEASYLPVS Sbjct: 1079 IVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVS 1138 Query: 1133 FETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSV 1192 FET+RVY + GRH RCRA LTNL DGG GK+GRI L +DAG++ E++ IYLRRVERR+V Sbjct: 1139 FETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDAGHIAAEVDGIYLRRVERRAV 1197 Query: 1193 PLPLAQKIFDTEWVEKSIAGADQPD-----APGSWLVLTD----------AKSNADEFVA 1237 PLPL QKIFD EW E IA P+ GSWLVL D AKS AD+FV Sbjct: 1198 PLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLADATVDAPGKAQAKSMADDFVQ 1257 Query: 1238 RWSSPQRRVITADLGDE 1254 +W SP RRV TAD+ DE Sbjct: 1258 QWRSPMRRVHTADIHDE 1274 >tr|A4KKJ4|A4KKJ4_MYCTU Tax_Id=395095 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsD;[Mycobacterium tuberculosis str. Haarlem] Length = 1485 Score = 1581 bits (4094), Expect = 0.0 Identities = 858/1473 (58%), Positives = 1005/1473 (68%), Gaps = 51/1473 (3%) Query: 344 TGTV-LGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAH 402 TGT GDPIE A G G+ + LG + + AA + ++ LAV Sbjct: 6 TGTERCGDPIESSRCATMPGKGRARAR--AHLG--RQDQHRAPEAAAVCWIHQSVLAVQR 61 Query: 403 GYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAGLRRAAVSSFGL----SGTNAHVVLE 458 G+IP N + N S+ R + + P G + G+ NAHVV+E Sbjct: 62 GHIPRNFALTGGNRP---STRRRRGCSCRPKAPRGRGCRSTQGCGVIVRPQRANAHVVVE 118 Query: 459 QXXXXXXXDQPRSG-LSALVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHR 517 Q +SAL VSGKT RVA+ A+ LADW+ GPG PLADVAHTLN HR Sbjct: 119 QAPDTAVAAAGGMPYVSALNVSGKTAARVASAAAVLADWMSGPGAAAPLADVAHTLNRHR 178 Query: 518 ARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMG 577 ARH KF GLRALAAGQP GV+ C PG VFVYSGQGSQW MG Sbjct: 179 ARHAKFATVIARDRAEAIAGLRALAAGQPRVGVVDCDQHAGGPGRVFVYSGQGSQWASMG 238 Query: 578 RQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALW 637 +QLLA+EP+FA A+AEL+P FV Q GFSLQQTL +G EVVGIDRIQPVLVG+QLALT LW Sbjct: 239 QQLLANEPAFAKAVAELDPIFVDQVGFSLQQTLIDGDEVVGIDRIQPVLVGMQLALTELW 298 Query: 638 RSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXX 697 RS+GV PDAV+GHSMGEVSAAVVAGALTP G +VI TRSRLMARL+GQG Sbjct: 299 RSYGVIPDAVIGHSMGEVSAAVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDAD 358 Query: 698 XXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPII 757 YPQVTLAVHASP Q+V+AGPPE VD VIAAVA QNRLARR+EVDVASHHPII Sbjct: 359 AAEALIAGYPQVTLAVHASPRQTVIAGPPEQVDTVIAAVATQNRLARRVEVDVASHHPII 418 Query: 758 DPILPDLRSALADLTPQPPAIPMITTTCEQPQPVLDADYWAANLRNPVRFHQAITTAGAQ 817 DPILP+LRSALADLTPQPP+IP+I+TT E QPV DADYW+ANLRNPVRFHQA+T AG Sbjct: 419 DPILPELRSALADLTPQPPSIPIISTTYESAQPVADADYWSANLRNPVRFHQAVTAAGVD 478 Query: 818 HHTFVEISPHPLLTHAITDTLAAAESRTRLITATLQRDGDDAITFHTNLAAVGKKPADAV 877 H+TF+EISPHP+LTHA+TDTL S T + +T+ R+ D + FH LAAVG ++ Sbjct: 479 HNTFIEISPHPVLTHALTDTLDPDGSHT--VMSTMNRELDQTLYFHAQLAAVGVAASEHT 536 Query: 878 TGQLADIPVTPWQHTQFWVEDRSGISELVAAHPLLGVHIEVPSGHDHVWQADVGTKACPW 937 TG+L D+P TPW H +FWV DRS +SEL A HPLLG HIE+P DHVWQ DVGT+ CPW Sbjct: 537 TGRLVDLPPTPWHHQRFWVTDRSAMSELAATHPLLGAHIEMPRNGDHVWQTDVGTEVCPW 596 Query: 938 LGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVDALS----INQLEIEQMLDLDEHTQVT 993 L DHKVFGQ IMP DA++ INQ E+EQML LD HT +T Sbjct: 597 LADHKVFGQPIMPAAGFAEIALAAASEALGTAADAVAPNIVINQFEVEQMLPLDGHTPLT 656 Query: 994 TQLTRRADDKTRIEIYSRSASG-WRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADL 1052 TQL R D + R+EIYSR+ G + RHA AK E S A E T + PAD Sbjct: 657 TQLIRGGDSQIRVEIYSRTRGGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTVSPADF 716 Query: 1053 YALLRQAGQNHGPAFAALTRILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLA 1112 YALLRQ GQ+HGPAFAAL+RI+R DGS ETEI++ DEAPRH GYR+HP +LDAALQS+ Sbjct: 717 YALLRQTGQHHGPAFAALSRIVRLADGSAETEISIPDEAPRHPGYRLHPVVLDAALQSVG 776 Query: 1113 AAVPNDEFAGSAEASYLPVSFETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDA 1172 AA+P+ E AGSAEASYLPVSFET+RVY + GRH RCRA LTNL DGG GK+GRI L +DA Sbjct: 777 AAIPDGEIAGSAEASYLPVSFETIRVYRDIGRHVRCRAHLTNL-DGGTGKMGRIVLINDA 835 Query: 1173 GNVTVEINDIYLRRVERRSVPLPLAQKIFDTEWVEKSIAGADQPDAP-----GSWLVLTD 1227 G++ E++ IYLRRVERR+VPLPL QKIFD EW E IA P+ GSWLVL D Sbjct: 836 GHIAAEVDGIYLRRVERRAVPLPLEQKIFDAEWTESPIAAVPAPEPAAETTRGSWLVLAD 895 Query: 1228 A----------KSNADEFVARWSSPQRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXX 1277 A KS AD+FV +W SP RRV TAD+ DE GDPE P Sbjct: 896 ATVDAPGKAQAKSMADDFVQQWRSPMRRVHTADIHDESAVLAAFAETAGDPEHPPVGVVV 955 Query: 1278 XXXXXXXXXXXXXXXRISYDGLIQSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGL-V 1336 D L +RDTVW I+TVVRA+VGTWHGR+PRLWLVT GGL V Sbjct: 956 FVGGASSRLD---------DELAAARDTVWSITTVVRAVVGTWHGRSPRLWLVTGGGLSV 1006 Query: 1337 VHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGELSSPRDDPNYDDV 1396 DEPG PA +L+GLVRVLA+EHP++R TLVDLD D +T L+ EL + +DDV Sbjct: 1007 ADDEPGTPAAASLKGLVRVLAFEHPDMRTTLVDLDITQDPLTALSAELRNAGSGSRHDDV 1066 Query: 1397 VAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVV 1456 +AWR R+V +L RA +D + PV+R GASY+VT VVARWLVD GAGRVV Sbjct: 1067 IAWRGERRFVERLSRATIDVS-KGHPVVRQGASYVVTGGLGGLGLVVARWLVDRGAGRVV 1125 Query: 1457 LNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAV 1516 L GRS+P+DEQ VLAEL++RAE+VVV GD A+ GVAE L+ A QLRG+VH AAV Sbjct: 1126 LGGRSDPTDEQCNVLAELQTRAEIVVVRGDVASPGVAEKLIETARQSGGQLRGVVHAAAV 1185 Query: 1517 IDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYAC 1576 I+DSL+FSM++D+LERVWAPKA GALR+H+ATA ELDWWLGFSS ASLLGSPGQ AYAC Sbjct: 1186 IEDSLVFSMSRDNLERVWAPKATGALRMHEATADCELDWWLGFSSAASLLGSPGQAAYAC 1245 Query: 1577 ASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXX 1636 ASAWLD LV WRRA+GLPAA INWGPWSEVGVAQALVG+ LD I+ AEG+ Sbjct: 1246 ASAWLDALVGWRRASGLPAAVINWGPWSEVGVAQALVGSVLDTISVAEGIEALDSLLAAD 1305 Query: 1637 RGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQV 1696 R RTGVARLR+DRAL+AFPEIR++ YFT VV+EL P+AL ++DP EAR+ Sbjct: 1306 RIRTGVARLRADRALVAFPEIRSISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRA 1365 Query: 1697 VTERLHTRIAAVMGYADRSAVDASM----PLTELGLDSLMAVRIRNTARADFGVEPPVTL 1752 VTER+ RIAAVMGY D+S V+ ++ PLTELGLDSLMAVRIRN ARADFGVEPPV L Sbjct: 1366 VTERMCARIAAVMGYTDQSTVEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVAL 1425 Query: 1753 ILQGASLHDLTVDVIRQLDLAGDEQTHEHVDVV 1785 ILQGASLHDLT D++RQL L + + D + Sbjct: 1426 ILQGASLHDLTADLMRQLGLNDPDPALNNADTI 1458 >tr|B2HIM9|B2HIM9_MYCMM Tax_Id=216594 (ppsC)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsC;[Mycobacterium marinum] Length = 2201 Score = 1087 bits (2811), Expect = 0.0 Identities = 655/1478 (44%), Positives = 871/1478 (58%), Gaps = 97/1478 (6%) Query: 1 MTSLAERAAQMSPKAREV--LARELV---RAGTAFPTDIAEPVAVVGIGCRLPGNVSGPD 55 MT+ +R A ++ R++ L+ L +AGT EP+AVVG+GCR PG V P+ Sbjct: 1 MTATPDRRAVITDALRKIDDLSARLEIAEKAGT-------EPIAVVGMGCRFPGGVDNPE 53 Query: 56 SFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXT- 114 FW LL +GR + VP+ RWDADA Y D G + + + Sbjct: 54 QFWDLLHEGRSGIVRVPSQRWDADALYTDDHTLAGTICNREGGFLSTWEPSEFDAEFFSI 113 Query: 115 -PREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIV--NLERRA 171 PREA AMDPQQR+ LEVAWEALE+AG+PP ++ GT+T +G++A+DY ++ R Sbjct: 114 PPREAAAMDPQQRLFLEVAWEALENAGIPPQTIRGTQTGVFVGVTAYDYMLMMSGAVRAE 173 Query: 172 EIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALA 231 E+DAY+ TGN + A GR +YLLG RGPA+ +DTACSSSLVA+HLACQSLR RE+D+AL Sbjct: 174 ELDAYLLTGNSANFAAGRTAYLLGARGPAMVLDTACSSSLVAIHLACQSLRWRETDMALV 233 Query: 232 GGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDR 291 GG L+LSP TSIA S+W LSP G+CKTFDA ADG+VRSEG GVVVLKRL DA RDG+R Sbjct: 234 GGTNLLLSPGTSIACSRWGMLSPEGQCKTFDADADGYVRSEGAGVVVLKRLSDAQRDGNR 293 Query: 292 VLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDP 351 +LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL A T ++Y+E HGTGT LGDP Sbjct: 294 ILAVVRGSAVNQDGASSGVTVPNGPAQQALLAQALDSAKLTPADIDYIEAHGTGTPLGDP 353 Query: 352 IEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHF 411 IE ++L+ + +G + LG+VKTNLGHLEAAAGI F+K+ LAV HG IP NL+F Sbjct: 354 IELDSLSKVFA--DREGREPLVLGAVKTNLGHLEAAAGIAGFMKSVLAVGHGRIPRNLNF 411 Query: 412 SRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQP 469 + P +RL + T+ +WPA RRA VSSFG+SGTNAHVV+EQ + Sbjct: 412 RQLTPHASEGVSRLTIATEEMEWPATDQPRRAGVSSFGVSGTNAHVVIEQAPDPAPVPRD 471 Query: 470 RS-GLSALVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXX 528 + +S LVVSGKT QRVAA A+ALADW++GPG + PL+DVAHTLNHHRAR KF Sbjct: 472 AAPAVSTLVVSGKTAQRVAATAAALADWMEGPGSEVPLSDVAHTLNHHRARQPKFATVAA 531 Query: 529 XXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFA 588 GLRALAAG+P GV+GC + PGTVFVYSG+GSQW GMGRQLLADEP+FA Sbjct: 532 VDREQAITGLRALAAGEPATGVVGCPEKPLGPGTVFVYSGRGSQWAGMGRQLLADEPAFA 591 Query: 589 AAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVV 648 AAIAELEP F+A+AGFSL + +G+E+ GI++IQ L+G+QLALTALWR +GVTPD V+ Sbjct: 592 AAIAELEPVFLAEAGFSLHDVIADGKELEGIEQIQLGLIGMQLALTALWRHYGVTPDLVI 651 Query: 649 GHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQ 708 GHSMGEV+A VVAGALTPA+G +V ATRSRLMA L+GQG YP+ Sbjct: 652 GHSMGEVAATVVAGALTPAEGLRVTATRSRLMAPLSGQGTMAMLELDATATEALIAGYPE 711 Query: 709 VTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSAL 768 VTLA++ASP Q+V+AGPP+ +D +I V QNR A R+ ++VA H+P +D + P +RS L Sbjct: 712 VTLAIYASPRQTVIAGPPQMIDELIEQVRAQNRFAGRVNIEVAPHNPAMDALQPLMRSEL 771 Query: 769 ADLTPQPPAIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTA--GAQ--HHTFV 822 ADLTP+PP+IP+I+TT E + +P DA++WA N+RNPVRF QAIT A GA HHTF+ Sbjct: 772 ADLTPRPPSIPIISTTYEDLESRPAFDAEHWATNMRNPVRFQQAITHAFNGADTAHHTFI 831 Query: 823 EISPHPLLTHAITDTLAAAESRTR---------LITATLQRDGDDAITFHTNLAAV---- 869 EIS HPLLTHAI++TLAA++ + L TLQRD D +TFHTN A Sbjct: 832 EISAHPLLTHAISETLAASQDSAQGETDSGASYLSIGTLQRDAHDTLTFHTNFNATHTTR 891 Query: 870 -GKKPADAVTGQLADIPVTPWQHTQFWVEDRSGISELVAAHPLLGVHIEVPSGHDHVWQA 928 + P A + +P TPWQH Q W+ + +HPLLG+ + P+ VW++ Sbjct: 892 GPQTPHPAEPHPV--LPTTPWQHGQHWISSTTASRYATGSHPLLGIGVTDPTNGTRVWES 949 Query: 929 DVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXF-DLPVDALS------------- 974 +G WL DH + ++P F D D S Sbjct: 950 QLGPDLL-WLSDHVIDDLCVLPGSAYAEVALAAAMDTFKDAEGDQGSADPAGPDGSVASN 1008 Query: 975 ------INQLEIEQMLDLDEHTQVTTQLTRRADDKT-RIEIYSRS-ASGWRRHA---VAK 1023 I +L + Q+L + + T++ T LT D+ T RIEI ++S ASGW +HA +A+ Sbjct: 1009 AHQPWVIRELSLHQLLHVTDGTKLVTTLT--GDEHTCRIEISTQSGASGWVKHASATLAR 1066 Query: 1024 AETSTPSA-APGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVE 1082 + S A P +EE + DE D P LY LR AGQ HGPAF + + G+ Sbjct: 1067 HDASDSDAPRPAVEEAGAPTDELD--PEQLYQRLRGAGQQHGPAFRGIVGLAVTESGAAR 1124 Query: 1083 TEITLSDEAP-RHQGYRIHPAMLDAALQSLAA---AVPNDEFAGSAEASYLPVSFETLRV 1138 ++ L A ++G+ +HP M+D A+Q+L A A+ E S LP+ F + V Sbjct: 1125 ADVRLPSSARIGYRGFALHPVMMDIAVQTLGATRMALELAEQQDSGHTLVLPIRFAGIHV 1184 Query: 1139 YSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPLAQ 1198 Y + R L D +GR+TL D G + I+++ + + + P L Sbjct: 1185 YGDIAEGVRAIGSLA-ATDRPDRLVGRVTLVDPDGQPLLVIDEVEMAVLGSSASPTELTS 1243 Query: 1199 KIFDTEWVEKSIAGADQPDA-PGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXXX 1257 ++F EW K + DQ A PG+ L++ D ++ A +S V D+ Sbjct: 1244 RLFTLEWEPKPL---DQTAATPGAVLLIGDLGADDRLLPALQTSLTGSVAELDVVSPADA 1300 Query: 1258 XXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVWQISTVVRAIV 1317 R + + L Q R + I+ V + + Sbjct: 1301 AKLRAAI----TRTDARWQDIVVVCPPRAVDEALPQDAQLDLTQQRTLM--IADVAQTVT 1354 Query: 1318 GTWHGRAPRLWLVTEGG--LVVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLD-TGA 1374 +PRLW+VT G L DE A L+G+ RVL +EHPEL+ TLVD++ G Sbjct: 1355 RMGARNSPRLWIVTRGAQQLSPADEV-TLAQTQLRGIARVLTFEHPELKTTLVDIEGDGE 1413 Query: 1375 DSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 S+T L EL + D DD ++ RDG R+V +L A Sbjct: 1414 GSLTALTQELLAGAD----DDEISLRDGQRFVHRLVAA 1447 Score = 243 bits (621), Expect = 1e-61 Identities = 145/373 (38%), Positives = 203/373 (54%), Gaps = 10/373 (2%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P+ P++ P Y++ VVARWL + GAG +VLNGRSEPSD+ R + Sbjct: 1801 AIASPPPE--PLVSPEGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSEPSDDVRAAI 1858 Query: 1472 AELESRA-EVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 A+L S + VV GD A G AE LV ++ +L G++H A V+DD ++ +M++ + Sbjct: 1859 ADLSSGGTRIEVVTGDIAEPGTAERLVQTVQNSGFRLAGVLHSAMVLDDEIVLNMSESAA 1918 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+ PK AG+ RLH+ATA +LDWWL FSS ASLLG+PGQ +YA A++++DGLVA+RR+ Sbjct: 1919 RRVFTPKVAGSWRLHEATADLDLDWWLTFSSVASLLGAPGQGSYAAANSFVDGLVAYRRS 1978 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 GLPA INWGPW+EVG AQ + IT +G+ R RTGV L + + Sbjct: 1979 LGLPAVGINWGPWAEVGRAQFFADLGVSMITVEQGLAAMQLVLSADRARTGVFILDARQW 2038 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXPE--ALKEMDPAEARQVVTERLHTRIAAV 1708 +FP F+ + + E AL+ AE + + I AV Sbjct: 2039 FQSFPAAAGSSLFSKLQESTTPERRAGGAIRAELDALEGAAAAERPARLAAAIAGEIRAV 2098 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + +D P+ LGLDSLMA+ +RN A G P L+ ++ DL + Sbjct: 2099 L--RSTEPIDVDRPMESLGLDSLMALELRNRLEASLGTTLPAALVWAYPTITDLAGALCE 2156 Query: 1769 QL---DLAGDEQT 1778 +L LA EQT Sbjct: 2157 RLGYAQLADVEQT 2169 >tr|A0PQ37|A0PQ37_MYCUA Tax_Id=362242 (ppsC)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsC;[Mycobacterium ulcerans] Length = 2201 Score = 1079 bits (2791), Expect = 0.0 Identities = 652/1478 (44%), Positives = 868/1478 (58%), Gaps = 97/1478 (6%) Query: 1 MTSLAERAAQMSPKAREV--LARELV---RAGTAFPTDIAEPVAVVGIGCRLPGNVSGPD 55 MT+ +R A ++ R++ L+ L +AGT EP+AVVG+GCR PG V P+ Sbjct: 1 MTATPDRRAVITDALRKIDDLSARLEIAEKAGT-------EPIAVVGMGCRFPGGVDNPE 53 Query: 56 SFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXT- 114 FW LL +GR + VP+ RWDADA Y D G + + + Sbjct: 54 QFWDLLHEGRSGIVRVPSQRWDADALYTDDHTLAGTICNREGGFLSTWEPSEFDAEFFSI 113 Query: 115 -PREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIV--NLERRA 171 PREA AMDPQQR+ LEVAWEALE+AG+ P ++ GT+T +G++A+DY ++ R Sbjct: 114 PPREAAAMDPQQRLFLEVAWEALENAGISPQTIRGTQTGVFVGVTAYDYMLMMSGAVRAE 173 Query: 172 EIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALA 231 E+DAY+ TGN + A GR +YLLG RGPA+ +DTACSSSLVA+HLACQSLR RE+D+AL Sbjct: 174 ELDAYLLTGNSANFAAGRTAYLLGARGPAMVLDTACSSSLVAIHLACQSLRWRETDMALV 233 Query: 232 GGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDR 291 GG L+LSP TSIA S+W LSP G+CKTFDA ADG+VRSEG GVVVLKRL DA RDG+R Sbjct: 234 GGTNLLLSPGTSIACSRWGMLSPEGQCKTFDADADGYVRSEGAGVVVLKRLSDAQRDGNR 293 Query: 292 VLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDP 351 +LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL A T ++Y+E HGTGT LGDP Sbjct: 294 ILAVVRGSAVNQDGASSGVTVPNGPAQQALLAQALDSAKLTPADIDYIEAHGTGTPLGDP 353 Query: 352 IEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHF 411 IE ++L+ + +G + LG+VKTNLGHLEAAAGI F+K+ LAV HG IP NL+F Sbjct: 354 IELDSLSKVFA--DREGREPLVLGAVKTNLGHLEAAAGIAGFMKSVLAVGHGRIPRNLNF 411 Query: 412 SRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQP 469 + P +RL + T+ +WPA RRA VSSFG+SGTNAHVV+EQ + Sbjct: 412 RQLTPHASEGVSRLTIATEEMEWPATDQPRRAGVSSFGVSGTNAHVVIEQAPDPAPVPRD 471 Query: 470 RS-GLSALVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXX 528 + +S LVVSGKT QRVAA A+ALADW++GPG + PL+DVAHTLNHHRAR KF Sbjct: 472 AAPAVSTLVVSGKTAQRVAATAAALADWMEGPGSEVPLSDVAHTLNHHRARQPKFATVAA 531 Query: 529 XXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFA 588 GLRALAAG+P GV+GC + PGTVFVYSG+GSQW GMGRQLLADEP+FA Sbjct: 532 VDREQAITGLRALAAGEPATGVVGCPEKPLGPGTVFVYSGRGSQWAGMGRQLLADEPAFA 591 Query: 589 AAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVV 648 AAIAELEP F+A+AGFSL + +G+E+ GI++IQ L+G+QLALTALWR +GVTPD V+ Sbjct: 592 AAIAELEPVFLAEAGFSLHDVIADGKELEGIEQIQLGLIGMQLALTALWRHYGVTPDLVI 651 Query: 649 GHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQ 708 GHSMGEV+AAVVAGALTPA+G +V ATRSRLMA L+GQG YP+ Sbjct: 652 GHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPLSGQGTMAMLELDATATEALIAGYPE 711 Query: 709 VTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSAL 768 VTLA++ASP Q+V+AGPP+ +D +I V QNR A R+ ++VA H+P +D + P +RS L Sbjct: 712 VTLAIYASPRQTVIAGPPQMIDELIEQVRAQNRFAGRVNIEVAPHNPAMDALQPLMRSEL 771 Query: 769 ADLTPQPPAIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTA--GAQ--HHTFV 822 ADLTP+PP+ P+I+TT E + +P DA++WA N+RNPVRF QAIT A GA HHTF+ Sbjct: 772 ADLTPRPPSTPIISTTYEDLESRPAFDAEHWATNMRNPVRFQQAITHAFNGADTAHHTFI 831 Query: 823 EISPHPLLTHAITDTLAAAESRTR---------LITATLQRDGDDAITFHTNLAAV---- 869 EIS HPLLTHAI++TLAA + + L TLQRD D +TFHTN A Sbjct: 832 EISAHPLLTHAISETLAANQDSAQGETDSGASYLSIGTLQRDAHDTLTFHTNFNATHTTH 891 Query: 870 -GKKPADAVTGQLADIPVTPWQHTQFWVEDRSGISELVAAHPLLGVHIEVPSGHDHVWQA 928 + P A + +P TPWQH Q W+ + +HPLLG+ + P+ VW++ Sbjct: 892 GPQTPHPAEPHPV--LPTTPWQHGQHWISSTTASRYATGSHPLLGIGVTDPTNGTRVWES 949 Query: 929 DVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXF-DLPVDALS------------- 974 +G WLGDH + ++P F D D S Sbjct: 950 QLGPDLL-WLGDHVIDDLCVLPGSAYAEVALAAAMDTFKDAEGDQGSADPAGPDGSVASN 1008 Query: 975 ------INQLEIEQMLDLDEHTQVTTQLTRRADDKT-RIEIYSRS-ASGWRRHA---VAK 1023 I +L + Q+L + + T++ T LT D+ T RIEI ++S ASGW +HA +A+ Sbjct: 1009 AHQPWVIRELSLHQLLHVTDGTKLVTTLT--GDEHTCRIEISTQSGASGWVKHASATLAR 1066 Query: 1024 AETSTPSA-APGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVE 1082 + S A P +E+ + DE D P LY LR AGQ HGPAF + + G+ Sbjct: 1067 HDASDSDAPRPAVEKAGAPTDELD--PEQLYQRLRGAGQQHGPAFRGIVGLAVTGSGAAR 1124 Query: 1083 TEITLSDEAP-RHQGYRIHPAMLDAALQSLAA---AVPNDEFAGSAEASYLPVSFETLRV 1138 ++ L A ++G+ +HP M+D A+Q+L A A+ E S LP+ F + V Sbjct: 1125 ADVRLPSSARIGYRGFALHPVMMDIAVQTLGATRMALELTEQQDSGHTLVLPIRFAGIHV 1184 Query: 1139 YSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPLAQ 1198 Y + R L D +GR+TL D G + I+++ + + + P L Sbjct: 1185 YGDIAEGVRAIGSLA-ATDRPDRLVGRVTLVDPDGQPLLVIDEVEMAVLGSSASPTELTS 1243 Query: 1199 KIFDTEWVEKSIAGADQPDA-PGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXXX 1257 ++F EW K + DQ A PG+ L++ D ++ A +S D+ Sbjct: 1244 RLFTLEWEPKPL---DQTAATPGAVLLIGDLGADDRLLPALQTSLTGSAAELDVVSPADA 1300 Query: 1258 XXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVWQISTVVRAIV 1317 R + + L Q R + I+ V + + Sbjct: 1301 AKLRAAI----TRTDARWQDIVVVCPPRAVDEALPQDAQLDLTQQRTLM--IADVAQTVT 1354 Query: 1318 GTWHGRAPRLWLVTEGG--LVVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLD-TGA 1374 +PRLW+VT G L DE A L+G+ RVL +EHPEL+ TLVD++ G Sbjct: 1355 RMGARNSPRLWIVTRGAQQLSPADEV-TLAQTQLRGIARVLIFEHPELKTTLVDIEGDGE 1413 Query: 1375 DSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 S+ L EL + D DD ++ RDG R+V +L A Sbjct: 1414 GSLAALTQELLAGAD----DDEISLRDGQRFVHRLVAA 1447 Score = 243 bits (619), Expect = 2e-61 Identities = 142/367 (38%), Positives = 200/367 (54%), Gaps = 8/367 (2%) Query: 1418 PQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESR 1477 P +P++ P Y++ VVARWL + GAG +VLNGRSEPSD+ R +A+L S Sbjct: 1805 PPPEPLVSPEGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSEPSDDVRAAIADLSSG 1864 Query: 1478 A-EVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAP 1536 + VV GD A G AE LV ++ +L G++H A V+DD ++ +M++ + RV+ P Sbjct: 1865 GTRIEVVTGDIAEPGTAERLVQTVQNSGFRLAGVLHSAMVLDDEIVLNMSESAARRVFTP 1924 Query: 1537 KAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAA 1596 K AG+ RLH+ATA +LDWWL FSS ASLLG+PGQ +YA A++++DGLVA+RR+ GLPA Sbjct: 1925 KVAGSWRLHEATADLDLDWWLTFSSVASLLGAPGQGSYAAANSFVDGLVAYRRSLGLPAV 1984 Query: 1597 TINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPE 1656 INWGPW+EVG AQ + IT +G+ R RTGV L + + +FP Sbjct: 1985 GINWGPWAEVGRAQFFADLGVSMITVEQGLAAMQLVLSADRARTGVFILDARQWFQSFPA 2044 Query: 1657 IRNLGYFTLVVQELXXXXXXXXXXXPE--ALKEMDPAEARQVVTERLHTRIAAVMGYADR 1714 F+ + + E AL+ AE + + I AV+ Sbjct: 2045 AAGSSLFSKLQESTTPERRAGGAIRAELDALERAAAAELPARLAGAIAGEIRAVL--RST 2102 Query: 1715 SAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIRQL---D 1771 +D P+ LGLDSLMA+ +RN A G P L+ ++ DL + +L Sbjct: 2103 EPIDVDRPMESLGLDSLMALELRNRLEASLGTTLPAALVWAYPTITDLAGALCERLGYAQ 2162 Query: 1772 LAGDEQT 1778 LA EQT Sbjct: 2163 LADVEQT 2169 >tr|Q49933|Q49933_MYCLE Tax_Id=1769 SubName: Full=Polyketide synthase; SubName: Full=PksD;[Mycobacterium leprae] Length = 2201 Score = 1075 bits (2779), Expect = 0.0 Identities = 639/1450 (44%), Positives = 844/1450 (58%), Gaps = 100/1450 (6%) Query: 36 EPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM--T 93 EP+AV+G+GCR PG V+ P+ FW LL DGR + VP+DRWDADA+Y D PG + T Sbjct: 35 EPIAVIGMGCRFPGGVNNPEQFWDLLCDGRSGIVRVPSDRWDADAYYTDDHTVPGTICST 94 Query: 94 TKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAA 153 +PREA AMDPQQR+L+EVAWEALE AG+ P ++ GT+T+ Sbjct: 95 EGGFLTGWQPDEFDAEFFSISPREASAMDPQQRLLIEVAWEALEDAGVAPHTIRGTQTSV 154 Query: 154 VMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSL 211 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG+RGPAV +DTACSSSL Sbjct: 155 FVGVTAYDYMLTLAGRLRPEDLDAYIPTGNSANFAAGRLAYILGVRGPAVVIDTACSSSL 214 Query: 212 VALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRS 271 VA+HLACQSLR RESD AL GG L+LSP SIA S+W LSP G+CK FD ADG+VR Sbjct: 215 VAVHLACQSLRHRESDAALVGGTNLLLSPGPSIACSRWGMLSPAGQCKAFDVSADGYVRG 274 Query: 272 EGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADA 331 EG GVVVLKRL DAVRDG+R+LA+VRGSA+NQDG S+G+T PN AQ++++ TAL + Sbjct: 275 EGAGVVVLKRLDDAVRDGNRILAIVRGSAVNQDGASSGVTVPNGPAQQELLRTALASSKL 334 Query: 332 TADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDK-GADSCALGSVKTNLGHLEAAAGI 390 TA ++Y+E HGTGT LGDPIE ++L+ + + + G+ +GSVKTNLGHLEAAAGI Sbjct: 335 TAADIDYIEAHGTGTPLGDPIELDSLSKVFSDRQSRRGSVPLVIGSVKTNLGHLEAAAGI 394 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPA--GLRRAAVSSFGL 448 FIKA LAV G+IP +L+F + +++RL + ++G +WP RRA VSSFG+ Sbjct: 395 AGFIKAVLAVQRGFIPRHLNFHQLTTHASEAASRLNIASEGLEWPTVGRPRRAGVSSFGV 454 Query: 449 SGTNAHVVLEQXXXXXXXDQPRSGL------SALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVVLEQ P L S LVVSGKT QRVAA AS LADW++GPG Sbjct: 455 SGTNAHVVLEQAPDPVAVPAPGPALRLVPAVSTLVVSGKTVQRVAATASVLADWMEGPGA 514 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PL DVAHTLNHHRARH KF GLRALAAGQ GV+ +D PGT Sbjct: 515 AVPLTDVAHTLNHHRARHTKFGTVAAVDRGQAVAGLRALAAGQSTSGVVAPRDSVVGPGT 574 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQL+ADEP+FA AIA+LE +FV QAGFSL + + G+E+VGI++I Sbjct: 575 VFVYSGRGSQWAGMGRQLMADEPAFAEAIAKLEHEFVVQAGFSLHEVIANGKELVGIEQI 634 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALT LWRS+GV PDAV+GHSMGEV+AAVVAGALTP G +V ATRSRLMA Sbjct: 635 QLGLMGMQLALTELWRSYGVEPDAVIGHSMGEVAAAVVAGALTPTQGLRVTATRSRLMAP 694 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YPQV+L ++ASP Q+V+AGP +DA+I V Q+ Sbjct: 695 LSGQGTMALLELDAVATEALIADYPQVSLGIYASPRQTVIAGPTAMIDALIDKVRQQDGF 754 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ--PQPVLDADYWAAN 800 A R+ ++VA H+P +D + P +RS LADLTPQ P IP+I+TT E PV D ++WA N Sbjct: 755 ATRVNIEVAPHNPAMDALQPQMRSELADLTPQQPTIPIISTTYEDFGSTPVFDVEHWATN 814 Query: 801 LRNPVRFHQAITTA----GAQHHTFVEISPHPLLTHAITDTLAA--------AESRTRLI 848 +RNPVRF QAIT A G +HTF+EIS HPLLTH+I+D L + A L Sbjct: 815 MRNPVRFQQAITHASSGVGGDYHTFIEISAHPLLTHSISDILCSIAGTAEENAVGAGYLS 874 Query: 849 TATLQRDGDDAITFHTNLAA--VGKKPADAVTGQLADI-PVTPWQHTQFWVEDRSGISEL 905 TLQRD D + FHTNL A + P + + P+TPWQHT+ W+ S Sbjct: 875 IGTLQRDAHDTLEFHTNLNATHTSRPPRTPHPPEPHPVLPITPWQHTRHWISAMSAAYHR 934 Query: 906 VAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXX 965 HPLLGV + P+ VW++ +G WLGDH + ++P Sbjct: 935 ADTHPLLGVGVTDPTSGTRVWESQLGPDLL-WLGDHVIDDLCVLPGAAYAEVALAAATDT 993 Query: 966 F-------DLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA-SGWR 1017 F D P I +L++ Q+L + E T + T LT + RIE+ +R+ SGW Sbjct: 994 FPNERVEGDQP---WMIYELDLHQVLHVTEGTVLVTTLT-GDQQRCRIEMRTRNGFSGWT 1049 Query: 1018 RHAVAKAETSTPSAAPGLEERTSRQDET--DIKPADLYALLRQAGQNHGPAFAALTRILR 1075 HA A + EERT+ + ++ P DLY L AGQ HGPAF + + Sbjct: 1050 THATATVGPAESVQPSDREERTATPVDVVDELGPEDLYQRLCSAGQQHGPAFQGIVGLAV 1109 Query: 1076 RPDGSVETEITLSDEAPRHQGYR---IHPAMLDAALQSLAAAVPNDEFAGSAEAS---YL 1129 G+ E+ L A G+R +HP M+D ALQ+L A + AG A L Sbjct: 1110 EESGAARAEVRLPSSA--RMGFRDFLLHPVMMDIALQTLGATRMATDLAGGPTARKTLVL 1167 Query: 1130 PVSFETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVER 1189 PV F + VY + R C L +G +G + LTD G + I+++ + + Sbjct: 1168 PVRFAGVHVYGDVTRGV-CAVGLLTATEGLDRLVGEVVLTDLDGQPLLVIDEVQMTVLGA 1226 Query: 1190 RSVPLPLAQKIFDTEWVEKSI-AGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVIT 1248 S L ++F EW + + A G L++ D + +A SS + R+ Sbjct: 1227 GSDATELTDRLFTLEWEPTPLYKEVSRSSAQGGLLLIGDVAAGDPLLLALQSSLRARL-- 1284 Query: 1249 ADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI-------- 1300 E D +L IS+DG++ Sbjct: 1285 ----SENGPPPVDCVSFSDEVKLQAAITRTD--------------ISWDGIVVVCPPRAS 1326 Query: 1301 -----------QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGA 1348 ++ QI+ VV+A+ ++PRLW+VT G ++ E A Sbjct: 1327 DESLPDDAQLELAQTRTLQIAGVVQAVTQMGARKSPRLWIVTRGAQQLNAGESVTLAQTE 1386 Query: 1349 LQGLVRVLAYEHPELRATLVDLDT-GADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVT 1407 L+G+VRVL +EH EL+ATL+D++ G DS+ L EL + N+D+ VA+RDG RYV Sbjct: 1387 LRGIVRVLTFEHSELKATLLDIEADGTDSLDDLTEELLA---GSNHDE-VAYRDGQRYVN 1442 Query: 1408 QLCRAILDPE 1417 +L A + P+ Sbjct: 1443 RLVPAPITPK 1452 Score = 239 bits (609), Expect = 3e-60 Identities = 140/375 (37%), Positives = 196/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y+V V ARWL + GAG +VLNGRS PSD+ + Sbjct: 1801 AIASPPPV--PLVSQDGGYLVVGGMGGLGFVFARWLAEQGAGLIVLNGRSSPSDDVTAAI 1858 Query: 1472 AELESRAE-VVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 A+L + + VV GD + G A+ LV A + +L G++H A V+ D ++ +MT + Sbjct: 1859 ADLTAAGHRIEVVTGDISEPGTADRLVHAVQSAGFRLAGVLHSAMVLADEIMLNMTDSAA 1918 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+ PK G+ RLH ATA E+DWWL FSS +SLLG+PGQ AYA A+AW+DGLVA+RR+ Sbjct: 1919 RRVFVPKVTGSWRLHQATAAFEVDWWLTFSSASSLLGTPGQGAYAAANAWVDGLVAYRRS 1978 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 GLPA INWGPW+EVG AQ G + +T +G+ R +TGV L + + Sbjct: 1979 LGLPAVGINWGPWAEVGRAQFFAGLGVSLLTAEQGLAAMQTVLAADRAQTGVFSLDARQW 2038 Query: 1651 LIAFPEIRNLGYFTLV--VQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L L +D AE + + I AV Sbjct: 2039 FQSFPAVAGSSLFANLRDTATLKSGERRGVGKIRAQLDVLDAAERPGHLASAIADEIRAV 2098 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + +D +D PL LGLDSLM + +RN A G+ PV L+ + DL + Sbjct: 2099 LRSSD--PIDHDRPLEALGLDSLMGLELRNRLEASLGITLPVALVWAYPTTADLAAALCE 2156 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A + E D Sbjct: 2157 RMDYALPAEVQEATD 2171 >tr|B8ZT38|B8ZT38_MYCLB Tax_Id=561304 SubName: Full=Polyketide synthase;[Mycobacterium leprae] Length = 2201 Score = 1075 bits (2779), Expect = 0.0 Identities = 639/1450 (44%), Positives = 844/1450 (58%), Gaps = 100/1450 (6%) Query: 36 EPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM--T 93 EP+AV+G+GCR PG V+ P+ FW LL DGR + VP+DRWDADA+Y D PG + T Sbjct: 35 EPIAVIGMGCRFPGGVNNPEQFWDLLCDGRSGIVRVPSDRWDADAYYTDDHTVPGTICST 94 Query: 94 TKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAA 153 +PREA AMDPQQR+L+EVAWEALE AG+ P ++ GT+T+ Sbjct: 95 EGGFLTGWQPDEFDAEFFSISPREASAMDPQQRLLIEVAWEALEDAGVAPHTIRGTQTSV 154 Query: 154 VMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSL 211 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG+RGPAV +DTACSSSL Sbjct: 155 FVGVTAYDYMLTLAGRLRPEDLDAYIPTGNSANFAAGRLAYILGVRGPAVVIDTACSSSL 214 Query: 212 VALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRS 271 VA+HLACQSLR RESD AL GG L+LSP SIA S+W LSP G+CK FD ADG+VR Sbjct: 215 VAVHLACQSLRHRESDAALVGGTNLLLSPGPSIACSRWGMLSPAGQCKAFDVSADGYVRG 274 Query: 272 EGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADA 331 EG GVVVLKRL DAVRDG+R+LA+VRGSA+NQDG S+G+T PN AQ++++ TAL + Sbjct: 275 EGAGVVVLKRLDDAVRDGNRILAIVRGSAVNQDGASSGVTVPNGPAQQELLRTALASSKL 334 Query: 332 TADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDK-GADSCALGSVKTNLGHLEAAAGI 390 TA ++Y+E HGTGT LGDPIE ++L+ + + + G+ +GSVKTNLGHLEAAAGI Sbjct: 335 TAADIDYIEAHGTGTPLGDPIELDSLSKVFSDRQSRRGSVPLVIGSVKTNLGHLEAAAGI 394 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPA--GLRRAAVSSFGL 448 FIKA LAV G+IP +L+F + +++RL + ++G +WP RRA VSSFG+ Sbjct: 395 AGFIKAVLAVQRGFIPRHLNFHQLTTHASEAASRLNIASEGLEWPTVGRPRRAGVSSFGV 454 Query: 449 SGTNAHVVLEQXXXXXXXDQPRSGL------SALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVVLEQ P L S LVVSGKT QRVAA AS LADW++GPG Sbjct: 455 SGTNAHVVLEQAPDPVAVPAPGPALRLVPAVSTLVVSGKTVQRVAATASVLADWMEGPGA 514 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PL DVAHTLNHHRARH KF GLRALAAGQ GV+ +D PGT Sbjct: 515 AVPLTDVAHTLNHHRARHTKFGTVAAVDRGQAVAGLRALAAGQSTSGVVAPRDSVVGPGT 574 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQL+ADEP+FA AIA+LE +FV QAGFSL + + G+E+VGI++I Sbjct: 575 VFVYSGRGSQWAGMGRQLMADEPAFAEAIAKLEHEFVVQAGFSLHEVIANGKELVGIEQI 634 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALT LWRS+GV PDAV+GHSMGEV+AAVVAGALTP G +V ATRSRLMA Sbjct: 635 QLGLMGMQLALTELWRSYGVEPDAVIGHSMGEVAAAVVAGALTPTQGLRVTATRSRLMAP 694 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YPQV+L ++ASP Q+V+AGP +DA+I V Q+ Sbjct: 695 LSGQGTMALLELDAVATEALIADYPQVSLGIYASPRQTVIAGPTAMIDALIDKVRQQDGF 754 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ--PQPVLDADYWAAN 800 A R+ ++VA H+P +D + P +RS LADLTPQ P IP+I+TT E PV D ++WA N Sbjct: 755 ATRVNIEVAPHNPAMDALQPQMRSELADLTPQQPTIPIISTTYEDFGSTPVFDVEHWATN 814 Query: 801 LRNPVRFHQAITTA----GAQHHTFVEISPHPLLTHAITDTLAA--------AESRTRLI 848 +RNPVRF QAIT A G +HTF+EIS HPLLTH+I+D L + A L Sbjct: 815 MRNPVRFQQAITHASSGVGGDYHTFIEISAHPLLTHSISDILCSIAGTAEENAVGAGYLS 874 Query: 849 TATLQRDGDDAITFHTNLAA--VGKKPADAVTGQLADI-PVTPWQHTQFWVEDRSGISEL 905 TLQRD D + FHTNL A + P + + P+TPWQHT+ W+ S Sbjct: 875 IGTLQRDAHDTLEFHTNLNATHTSRPPRTPHPPEPHPVLPITPWQHTRHWISAMSAAYHR 934 Query: 906 VAAHPLLGVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXX 965 HPLLGV + P+ VW++ +G WLGDH + ++P Sbjct: 935 ADTHPLLGVGVTDPTSGTRVWESQLGPDLL-WLGDHVIDDLCVLPGAAYAEVALAAATDT 993 Query: 966 F-------DLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSA-SGWR 1017 F D P I +L++ Q+L + E T + T LT + RIE+ +R+ SGW Sbjct: 994 FPNERVEGDQP---WMIYELDLHQVLHVTEGTVLVTTLT-GDQQRCRIEMRTRNGFSGWT 1049 Query: 1018 RHAVAKAETSTPSAAPGLEERTSRQDET--DIKPADLYALLRQAGQNHGPAFAALTRILR 1075 HA A + EERT+ + ++ P DLY L AGQ HGPAF + + Sbjct: 1050 THATATVGPAESVQPSDREERTATPVDVVDELGPEDLYQRLCSAGQQHGPAFQGIVGLAV 1109 Query: 1076 RPDGSVETEITLSDEAPRHQGYR---IHPAMLDAALQSLAAAVPNDEFAGSAEAS---YL 1129 G+ E+ L A G+R +HP M+D ALQ+L A + AG A L Sbjct: 1110 EESGAARAEVRLPSSA--RMGFRDFLLHPVMMDIALQTLGATRMATDLAGGPTARKTLVL 1167 Query: 1130 PVSFETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVER 1189 PV F + VY + R C L +G +G + LTD G + I+++ + + Sbjct: 1168 PVRFAGVHVYGDVTRGV-CAVGLLTATEGLDRLVGEVVLTDLDGQPLLVIDEVQMTVLGA 1226 Query: 1190 RSVPLPLAQKIFDTEWVEKSI-AGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVIT 1248 S L ++F EW + + A G L++ D + +A SS + R+ Sbjct: 1227 GSDATELTDRLFTLEWEPTPLYKEVSRSSAQGGLLLIGDVAAGDPLLLALQSSLRARL-- 1284 Query: 1249 ADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI-------- 1300 E D +L IS+DG++ Sbjct: 1285 ----SENGPPPVDCVSFSDEVKLQAAITRTD--------------ISWDGIVVVCPPRAS 1326 Query: 1301 -----------QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGA 1348 ++ QI+ VV+A+ ++PRLW+VT G ++ E A Sbjct: 1327 DESLPDDAQLELAQTRTLQIAGVVQAVTQMGARKSPRLWIVTRGAQQLNAGESVTLAQTE 1386 Query: 1349 LQGLVRVLAYEHPELRATLVDLDT-GADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVT 1407 L+G+VRVL +EH EL+ATL+D++ G DS+ L EL + N+D+ VA+RDG RYV Sbjct: 1387 LRGIVRVLTFEHSELKATLLDIEADGTDSLDDLTEELLA---GSNHDE-VAYRDGQRYVN 1442 Query: 1408 QLCRAILDPE 1417 +L A + P+ Sbjct: 1443 RLVPAPITPK 1452 Score = 239 bits (609), Expect = 3e-60 Identities = 140/375 (37%), Positives = 196/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y+V V ARWL + GAG +VLNGRS PSD+ + Sbjct: 1801 AIASPPPV--PLVSQDGGYLVVGGMGGLGFVFARWLAEQGAGLIVLNGRSSPSDDVTAAI 1858 Query: 1472 AELESRAE-VVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 A+L + + VV GD + G A+ LV A + +L G++H A V+ D ++ +MT + Sbjct: 1859 ADLTAAGHRIEVVTGDISEPGTADRLVHAVQSAGFRLAGVLHSAMVLADEIMLNMTDSAA 1918 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+ PK G+ RLH ATA E+DWWL FSS +SLLG+PGQ AYA A+AW+DGLVA+RR+ Sbjct: 1919 RRVFVPKVTGSWRLHQATAAFEVDWWLTFSSASSLLGTPGQGAYAAANAWVDGLVAYRRS 1978 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 GLPA INWGPW+EVG AQ G + +T +G+ R +TGV L + + Sbjct: 1979 LGLPAVGINWGPWAEVGRAQFFAGLGVSLLTAEQGLAAMQTVLAADRAQTGVFSLDARQW 2038 Query: 1651 LIAFPEIRNLGYFTLV--VQELXXXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L L +D AE + + I AV Sbjct: 2039 FQSFPAVAGSSLFANLRDTATLKSGERRGVGKIRAQLDVLDAAERPGHLASAIADEIRAV 2098 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + +D +D PL LGLDSLM + +RN A G+ PV L+ + DL + Sbjct: 2099 LRSSD--PIDHDRPLEALGLDSLMGLELRNRLEASLGITLPVALVWAYPTTADLAAALCE 2156 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A + E D Sbjct: 2157 RMDYALPAEVQEATD 2171 >tr|Q7TXL8|Q7TXL8_MYCBO Tax_Id=1765 (ppsC)SubName: Full=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC;[Mycobacterium bovis] Length = 2188 Score = 1070 bits (2767), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLSIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 244 bits (622), Expect = 1e-61 Identities = 145/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ +MT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >tr|P96202|P96202_MYCTU Tax_Id=1773 (ppsC)SubName: Full=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC;[Mycobacterium tuberculosis] Length = 2188 Score = 1070 bits (2767), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLSIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 244 bits (622), Expect = 1e-61 Identities = 145/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ +MT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >tr|C6DWC1|C6DWC1_MYCTK Tax_Id=478434 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsC;[Mycobacterium tuberculosis] Length = 2188 Score = 1070 bits (2767), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLSIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 245 bits (625), Expect = 5e-62 Identities = 146/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ SMT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLSMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >tr|C1AG49|C1AG49_MYCBT Tax_Id=561275 (ppsC)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase;[Mycobacterium bovis] Length = 2188 Score = 1070 bits (2767), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLSIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 244 bits (622), Expect = 1e-61 Identities = 145/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ +MT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >tr|A5U6U0|A5U6U0_MYCTA Tax_Id=419947 (ppsC)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsC;[Mycobacterium tuberculosis] Length = 2188 Score = 1070 bits (2767), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLSIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 244 bits (622), Expect = 1e-61 Identities = 145/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ +MT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >tr|A1KMS8|A1KMS8_MYCBP Tax_Id=410289 (ppsC)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsC;[Mycobacterium bovis] Length = 2188 Score = 1070 bits (2767), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLSIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 244 bits (622), Expect = 1e-61 Identities = 145/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ +MT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >tr|A5WRI5|A5WRI5_MYCTF Tax_Id=336982 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsC;[Mycobacterium tuberculosis] Length = 2188 Score = 1070 bits (2767), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLSIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 244 bits (622), Expect = 1e-61 Identities = 145/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ +MT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >tr|Q7D6F1|Q7D6F1_MYCTU Tax_Id=1773 SubName: Full=Polyketide synthase;[Mycobacterium tuberculosis] Length = 2188 Score = 1070 bits (2766), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLRIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 244 bits (622), Expect = 1e-61 Identities = 145/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ +MT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >tr|A2VLR0|A2VLR0_MYCTU Tax_Id=348776 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsC;[Mycobacterium tuberculosis C] Length = 2188 Score = 1070 bits (2766), Expect = 0.0 Identities = 636/1437 (44%), Positives = 832/1437 (57%), Gaps = 99/1437 (6%) Query: 35 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRM-- 92 +EP+AV+G+GCR PG V+ P+ FW LL GR + VPA RWDADA+Y D PG + Sbjct: 34 SEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICS 93 Query: 93 TTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTA 152 T +PREA AMDPQQR+L+EVAWEALE AG+P ++ GT+T+ Sbjct: 94 TEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQHTIRGTQTS 153 Query: 153 AVMGLSAWDY--TIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSS 210 +G++A+DY T+ R ++DAYI TGN + A GR++Y+LG RGPAV +DTACSSS Sbjct: 154 VFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSS 213 Query: 211 LVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVR 270 LVA+HLACQSLR RESD+AL GG L+LSP SIA S+W LSP GRCKTFDA ADG+VR Sbjct: 214 LVAVHLACQSLRGRESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVR 273 Query: 271 SEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD 330 EG VVVLKRL DAVRDG+R+LAVVRGSA+NQDG S+G+T PN AQ+ ++ AL + Sbjct: 274 GEGAAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSK 333 Query: 331 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGI 390 TA ++YVE HGTGT LGDPIE ++L+ + G+D +GSVKTNLGHLEAAAG+ Sbjct: 334 LTAADIDYVEAHGTGTPLGDPIELDSLSKVFS--DRAGSDQLVIGSVKTNLGHLEAAAGV 391 Query: 391 TSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPAG--LRRAAVSSFGL 448 +KA LAV +GYIP +L+F + P +++RL + G WP RRA VSSFG+ Sbjct: 392 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGRPRRAGVSSFGV 451 Query: 449 SGTNAHVVLEQXXXXXXX--DQPRSG----LSALVVSGKTPQRVAAMASALADWVDGPGG 502 SGTNAHVV+EQ +P+ G +S LVV GKT RVAA AS LADW+DGPG Sbjct: 452 SGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGKTAPRVAATASVLADWLDGPGA 511 Query: 503 QTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGT 562 PLADVAHTLNHHRAR +F GLRALAAGQ PGV+ ++ GT Sbjct: 512 AVPLADVAHTLNHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGT 571 Query: 563 VFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRI 622 VFVYSG+GSQW GMGRQLLADEP+FAAAIAELEP+FVAQ GFSL+ + G+E+VGI++I Sbjct: 572 VFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQI 631 Query: 623 QPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMAR 682 Q L+G+QLALTALWRS+GVTPDAV+GHSMGEV+AAVVAGALTPA G +V A RSRLMA Sbjct: 632 QLGLIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAVRSRLMAP 691 Query: 683 LAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL 742 L+GQG YP+V+L ++ASP Q+V++GPP +D +I V QN Sbjct: 692 LSGQGTMALLELDAEATEALIADYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGF 751 Query: 743 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ------PQPVLDADY 796 A R+ ++VA H+P +D + P +RS LADLTPQPP IP+I+TT P DA++ Sbjct: 752 ATRVNIEVAPHNPAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEH 811 Query: 797 WAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAA-ESRTRLITATLQRD 855 WA N+RNPVRFHQAI AGA HHTF+EIS HPLLTH+I+DTL A+ + L TLQRD Sbjct: 812 WATNMRNPVRFHQAIAHAGADHHTFIEISAHPLLTHSISDTLRASYDVDNYLRIGTLQRD 871 Query: 856 GDDAITFHTNLAAVGKKPADAVTGQLAD---IPVTPWQHTQFWVEDRSGISELVAAHPLL 912 D + FHTNL +P TPWQHTQ W+ S HPLL Sbjct: 872 AHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSAAYHRPDTHPLL 931 Query: 913 GVHIEVPSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVD- 971 GV + P+ VW++++ WL DH + ++P F + D Sbjct: 932 GVGVTDPTNGTRVWESELDPDLL-WLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQ 990 Query: 972 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRS-ASGWRRHA---VAKAETS 1027 I++L++ QML + T + T LT + + ++EI +RS +SGW HA VA+AE Sbjct: 991 PWMISELDLRQMLHVTPGTVLVTTLT-GDEQRCQVEIRTRSGSSGWTTHATATVARAEPL 1049 Query: 1028 TPSAAPGLEERTSRQD-ETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVETEIT 1086 P G + D E + P DLY LR AGQ HGPAF + + G ++ Sbjct: 1050 APLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVR 1109 Query: 1087 LSDEA-PRHQGYRIHPAMLDAALQSLAAAVPNDEFAG---------SAEASYLPVSFETL 1136 L A + + +HP M+D ALQ+L A + AG S A +PV F + Sbjct: 1110 LPASARTGSREFMLHPVMMDIALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGV 1169 Query: 1137 RVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEINDIYLRRVERRSVPLPL 1196 VY + R R + +L G +G + LTD G + ++++ + + S L Sbjct: 1170 HVYGDITRGVRA---VGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGATEL 1226 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFVARWSSPQRRVITADLGDEXX 1256 ++F EW + +A G+ L++ D + A SS + R+ +L Sbjct: 1227 TNRLFMLEWEPAPL--EKTAEATGALLLIGDPAAGDPLLPALQSSLRDRITDLELAS--- 1281 Query: 1257 XXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLI---------------- 1300 D L R S+DG++ Sbjct: 1282 --------AADEATL----------------RAAISRTSWDGIVVVCPPRANDESMPDEA 1317 Query: 1301 ---QSRDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVH-DEPGRPAIGALQGLVRVL 1356 +R +++VV + ++PRLW+VT G E A L+G+ RVL Sbjct: 1318 QLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIARVL 1377 Query: 1357 AYEHPELRATLVDLD-TGADSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRA 1412 +EH EL TLVD++ G S+ LA EL + + D VA RDG RYV +L A Sbjct: 1378 TFEHSELNTTLVDIEPDGTGSLAALAEELLAGSE----ADEVALRDGQRYVNRLVPA 1430 Score = 244 bits (622), Expect = 1e-61 Identities = 145/375 (38%), Positives = 197/375 (52%), Gaps = 7/375 (1%) Query: 1412 AILDPEPQRDPVIRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVL 1471 AI P P P++ Y++ VVARWL + GAG +VLNGRS PSDE + Sbjct: 1788 AIAAPPPL--PLVSRDGGYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAI 1845 Query: 1472 AELE-SRAEVVVVCGDSATEGVAESLVAAAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSL 1530 AEL S + + V+ GD AE LV A ED +L G+VH A V+ D ++ +MT + Sbjct: 1846 AELNASGSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAA 1905 Query: 1531 ERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRA 1590 RV+APK G+ RLH ATA R++DWWL FSS A+LLG+PGQ AYA A++W+DGLVA RR+ Sbjct: 1906 RRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHRRS 1965 Query: 1591 AGLPAATINWGPWSEVGVAQALVGTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRA 1650 AGLPA INWGPW++VG AQ ++ I +G+ RGRTGV L + + Sbjct: 1966 AGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRGRTGVFSLDARQW 2025 Query: 1651 LIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP--EALKEMDPAEARQVVTERLHTRIAAV 1708 +FP + F + L +D AE + + I AV Sbjct: 2026 FQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLDALDAAERPGHLASAIADEIRAV 2085 Query: 1709 MGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDVIR 1768 + D +D PL LGLDSLM + +RN A G+ PV L+ ++ DL + Sbjct: 2086 LRSGD--PIDHHRPLETLGLDSLMGLELRNRLEASLGITLPVALVWAYPTISDLATALCE 2143 Query: 1769 QLDLAGDEQTHEHVD 1783 ++D A E D Sbjct: 2144 RMDYATPAAAQEISD 2158 >sp|Q10978|PPSB_MYCTU Tax_Id=1773 (ppsB)RecName: Full=Phenolpthiocerol synthesis polyketide synthase ppsB;[Mycobacterium tuberculosis] Length = 1538 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 2 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 58 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 59 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 118 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 119 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 178 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 179 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 238 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 239 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 298 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 299 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 358 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 359 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 414 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 415 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 474 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 475 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 534 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 535 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 594 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 595 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 654 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 655 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 714 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 715 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 774 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 775 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLL 834 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 835 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 894 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 895 TIPTTPWQHTHHWI 908 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1052 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1111 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1112 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1167 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1168 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1225 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1226 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFVLFSSV 1285 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1286 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1345 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1346 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1402 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1403 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1462 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1463 TLQRALSESLGEFLPASVVFDYPTVYSLT 1491 >tr|Q7TXL9|Q7TXL9_MYCBO Tax_Id=1765 (ppsB)SubName: Full=PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB;[Mycobacterium bovis] Length = 1538 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 2 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 58 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 59 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 118 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 119 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 178 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 179 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 238 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 239 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 298 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 299 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 358 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 359 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 414 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 415 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 474 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 475 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 534 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 535 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 594 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 595 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 654 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 655 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 714 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 715 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 774 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 775 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLL 834 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 835 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 894 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 895 TIPTTPWQHTHHWI 908 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1052 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1111 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1112 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1167 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1168 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1225 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1226 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRLSLKSPVRHFVLFSSV 1285 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1286 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1345 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1346 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1402 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1403 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1462 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1463 TLQRALSESLGEFLPASVVFDYPTVYSLT 1491 >tr|C6DWC2|C6DWC2_MYCTK Tax_Id=478434 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsB;[Mycobacterium tuberculosis] Length = 1538 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 2 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 58 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 59 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 118 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 119 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 178 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 179 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 238 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 239 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 298 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 299 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 358 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 359 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 414 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 415 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 474 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 475 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 534 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 535 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 594 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 595 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 654 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 655 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 714 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 715 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 774 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 775 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLL 834 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 835 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 894 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 895 TIPTTPWQHTHHWI 908 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1052 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1111 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1112 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1167 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1168 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1225 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1226 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFVLFSSV 1285 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1286 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1345 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1346 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1402 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1403 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1462 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1463 TLQRALSESLGEFLPASVVFDYPTVYSLT 1491 >tr|C1AG48|C1AG48_MYCBT Tax_Id=561275 (ppsB)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase;[Mycobacterium bovis] Length = 1538 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 2 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 58 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 59 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 118 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 119 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 178 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 179 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 238 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 239 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 298 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 299 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 358 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 359 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 414 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 415 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 474 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 475 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 534 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 535 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 594 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 595 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 654 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 655 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 714 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 715 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 774 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 775 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGTYHTFIEISAHPLL 834 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 835 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 894 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 895 TIPTTPWQHTHHWI 908 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1052 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1111 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1112 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1167 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1168 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1225 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1226 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRLSLKSPVRHFVLFSSV 1285 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1286 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1345 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1346 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1402 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1403 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1462 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1463 TLQRALSESLGEFLPASVVFDYPTVYSLT 1491 >tr|A5U6T9|A5U6T9_MYCTA Tax_Id=419947 (ppsB)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsB;[Mycobacterium tuberculosis] Length = 1538 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 2 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 58 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 59 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 118 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 119 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 178 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 179 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 238 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 239 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 298 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 299 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 358 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 359 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 414 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 415 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 474 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 475 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 534 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 535 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 594 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 595 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 654 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 655 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 714 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 715 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 774 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 775 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLL 834 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 835 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 894 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 895 TIPTTPWQHTHHWI 908 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1052 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1111 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1112 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1167 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1168 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1225 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1226 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFVLFSSV 1285 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1286 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1345 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1346 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1402 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1403 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1462 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1463 TLQRALSESLGEFLPASVVFDYPTVYSLT 1491 >tr|A1KMS7|A1KMS7_MYCBP Tax_Id=410289 (ppsB)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsB;[Mycobacterium bovis] Length = 1538 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 2 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 58 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 59 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 118 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 119 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 178 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 179 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 238 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 239 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 298 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 299 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 358 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 359 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 414 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 415 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 474 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 475 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 534 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 535 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 594 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 595 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 654 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 655 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 714 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 715 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 774 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 775 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGTYHTFIEISAHPLL 834 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 835 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 894 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 895 TIPTTPWQHTHHWI 908 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1052 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1111 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1112 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1167 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1168 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1225 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1226 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRLSLKSPVRHFVLFSSV 1285 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1286 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1345 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1346 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1402 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1403 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1462 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1463 TLQRALSESLGEFLPASVVFDYPTVYSLT 1491 >tr|A5WRI4|A5WRI4_MYCTF Tax_Id=336982 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsB;[Mycobacterium tuberculosis] Length = 1537 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 1 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 57 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 58 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 117 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 118 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 177 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 178 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 237 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 238 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 297 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 298 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 357 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 358 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 413 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 414 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 473 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 474 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 533 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 534 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 593 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 594 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 653 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 654 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 713 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 714 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 773 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 774 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLL 833 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 834 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 893 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 894 TIPTTPWQHTHHWI 907 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1051 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1110 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1111 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1166 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1167 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1224 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1225 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFVLFSSV 1284 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1285 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1344 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1345 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1401 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1402 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1461 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1462 TLQRALSESLGEFLPASVVFDYPTVYSLT 1490 >tr|A4KKJ2|A4KKJ2_MYCTU Tax_Id=395095 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsB;[Mycobacterium tuberculosis str. Haarlem] Length = 1537 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 1 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 57 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 58 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 117 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 118 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 177 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 178 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 237 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 238 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 297 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 298 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 357 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 358 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 413 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 414 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 473 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 474 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 533 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 534 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 593 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 594 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 653 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 654 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 713 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 714 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 773 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 774 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLL 833 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 834 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 893 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 894 TIPTTPWQHTHHWI 907 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1051 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1110 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1111 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1166 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1167 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1224 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1225 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFVLFSSV 1284 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1285 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1344 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1345 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1401 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1402 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1461 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1462 TLQRALSESLGEFLPASVVFDYPTVYSLT 1490 >tr|A2VLQ9|A2VLQ9_MYCTU Tax_Id=348776 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsB;[Mycobacterium tuberculosis C] Length = 1538 Score = 1058 bits (2736), Expect = 0.0 Identities = 556/914 (60%), Positives = 649/914 (71%), Gaps = 25/914 (2%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R LA E R +AEPVAVVGIGCR PG+V GP+SFW Sbjct: 2 MRTAFSRISGMTAQQRTSLADEFDRVSRIA---VAEPVAVVGIGCRFPGDVDGPESFWDF 58 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV GR+A+ VPADRWDA+AFY PDP PGRMTTKW TPREA A Sbjct: 59 LVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAA 118 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALEHAG+PPDSL GTRTA +MG+ +Y + +DAY TG Sbjct: 119 MDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTG 178 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGPAVAVDTACSSSLVA+HLACQSLRLRE+D+ALAGGV + L P Sbjct: 179 NAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRP 238 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD+VLAVVRGSA Sbjct: 239 ETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSA 298 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ D DSVNYVE HGTGTVLGDPIEFEALAAT Sbjct: 299 VNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAAT 358 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG G D+CALG+VKTN+GHLEAAAGI FIKATLAV IPPNLHFS+WNPAIDA Sbjct: 359 YG----HGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDA 414 Query: 421 SSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGLSAL 476 +STR FVPTQ + WP G RRAAVSSFGL GTNAHV++EQ + +G+S L Sbjct: 415 ASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTL 474 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKT QR+AA A LADW++GPG + +ADVAHT+NHHRAR F Sbjct: 475 VVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIA 534 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAAGQ PGV+ QD PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 535 GLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 594 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 FV QAGFSL+ + G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHSMGEV+ Sbjct: 595 VFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVA 654 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V ATR+RLMA L+GQG YPQVT+ ++ S Sbjct: 655 AAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNS 714 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V+AGP E +D +IA V QNR A R+ ++VA H+P +D + P +RS LADLTP+ P Sbjct: 715 PRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTP 774 Query: 777 AIPMITTTCE--QPQPVLDADYWAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLL 830 I +I+TT QP+ DA++WA N+RNPVRF QAI +AG+ +HTF+EIS HPLL Sbjct: 775 TIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLL 834 Query: 831 THAITDTLAAAESRTR-----LITATLQRDGDDAITFHTNL--AAVGKKPADAVTGQ-LA 882 T AI DTL A T+ L TLQRD DD +TF TNL A + P + Sbjct: 835 TQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHP 894 Query: 883 DIPVTPWQHTQFWV 896 IP TPWQHT W+ Sbjct: 895 TIPTTPWQHTHHWI 908 Score = 113 bits (283), Expect = 2e-22 Identities = 110/449 (24%), Positives = 182/449 (40%), Gaps = 19/449 (4%) Query: 1325 PRLWLVTEGGLVVHD-EPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTRLAGE 1383 P+L+++T + + + P L GL R LA EHPE+ ++DLD + + Sbjct: 1052 PKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHV 1111 Query: 1384 LSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXXVV 1443 L++ D VV +R G R+V +L R L P + + AS +V + Sbjct: 1112 LTAAHGTDGEDQVV-YRSGARHVPRLQRRTL---PGKPVTLNADASQLVIGATGNIGPHL 1167 Query: 1444 ARWLVDSGAGRVVLNGRSEPS-DEQRKVLAELESRAEVVVVCGDSATEGVAESLVAAAED 1502 R L GA +V R + DE + LA + +++ V D+ ++L Sbjct: 1168 IRQLARMGAKTIVAMARKPGALDELTQCLAA--TGTDLIAVAADATDPAAMQTLFDRFGT 1225 Query: 1503 QQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSST 1562 + L GI A +LL MT D + ++ PK LH + + ++ FSS Sbjct: 1226 ELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFVLFSSV 1285 Query: 1563 ASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-----VAQALVGTPL 1617 + LLGS Y SA+LD RR GLPA ++WG W + Q + L Sbjct: 1286 SGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGL 1345 Query: 1618 DPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXX 1677 P+ E + + +D L+A R G +V +L Sbjct: 1346 QPMAD-EVAIGALPLVMNPDAAVATVVVAADWPLLA-AAYRTRGALR-IVDDLLPAPEDV 1402 Query: 1678 XXXXPE---ALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAV 1734 E +L+ + R ++ + + A VMG +D S +LG+DSLM+V Sbjct: 1403 GKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSV 1462 Query: 1735 RIRNTARADFGVEPPVTLILQGASLHDLT 1763 ++ G P +++ +++ LT Sbjct: 1463 TLQRALSESLGEFLPASVVFDYPTVYSLT 1491 >tr|Q9S384|Q9S384_MYCLE Tax_Id=1769 (MLCB12.01c)SubName: Full=Polyketide synthase; SubName: Full=Putative polyketide synthase;[Mycobacterium leprae] Length = 1540 Score = 1051 bits (2719), Expect = 0.0 Identities = 551/913 (60%), Positives = 644/913 (70%), Gaps = 32/913 (3%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R L E + +AEP+AVVGIGCR PG+V+GPDSFW L Sbjct: 1 MRTAFSRISGMTTQQRAALIEEFTKLSRIA---VAEPIAVVGIGCRFPGDVTGPDSFWDL 57 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L+DGR+A+ VPADRWDADAFYDPDP PGRMTTKW TPREA A Sbjct: 58 LIDGRNAISRVPADRWDADAFYDPDPLTPGRMTTKWGGFVSDIAGFDAAFFGITPREAAA 117 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALE+AG+PPDSL +RT ++G+ +Y + +DAY TG Sbjct: 118 MDPQQRILLEVAWEALENAGIPPDSLGNSRTGVMIGVYFNEYQSMLASSLENVDAYSGTG 177 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGP+VAVDTACSSSLVA+HLACQSLRLRE+D+ LAGGV + L P Sbjct: 178 NAHSITVGRISYLLGLRGPSVAVDTACSSSLVAVHLACQSLRLRETDLVLAGGVSITLRP 237 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD VLAVVRGSA Sbjct: 238 ETQIAISAWGLLSPHGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDLVLAVVRGSA 297 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ +D +SVNYVE+HGTGTVLGDPIEFEALAAT Sbjct: 298 VNQDGRSNGVTAPNTAAQCDVITDALRSSDVAPESVNYVESHGTGTVLGDPIEFEALAAT 357 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG +G +CALG+VKTNLGHLEAAAGI FIK LAV G IPPNLHFS+WNPAIDA Sbjct: 358 YG----RGESACALGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNLHFSQWNPAIDA 413 Query: 421 SSTRLFVPTQGAQWP-----AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGL 473 +STR FVPT+ + WP AG RRAAVSSFGL GTNAHVV+EQ + + + Sbjct: 414 ASTRFFVPTENSSWPISDGQAGPRRAAVSSFGLGGTNAHVVIEQGPELTPVTECSSNTAV 473 Query: 474 SALVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXX 533 S LVV+GKT RVAAMA LADWV+GPG + LADVAHTLNHHR+RH KF Sbjct: 474 STLVVTGKTASRVAAMAGMLADWVEGPGAEVALADVAHTLNHHRSRHAKFGTVVARDRIQ 533 Query: 534 XXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAE 593 GLRALAAG+ PGV+G QD GTVFVYSG+GSQW GMGRQLLADEP+F AA+AE Sbjct: 534 AVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGSQWAGMGRQLLADEPAFTAAVAE 593 Query: 594 LEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMG 653 LEP FV AGFSL L G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHS+G Sbjct: 594 LEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSLG 653 Query: 654 EVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAV 713 EV+AAVVAGALT A+G +V ATRSRLMA L+GQG Y QVTLA+ Sbjct: 654 EVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDYSQVTLAI 713 Query: 714 HASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTP 773 + SP Q+V+AGP E +D +I V QNR A R+ ++VA H+P +D + P +RS LAD+ P Sbjct: 714 YNSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADVAP 773 Query: 774 QPPAIPMITTTCEQ--PQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLT 831 + P IP+++TT PV DA +WA N+RNPV F QAI TAG H TF+EIS HPLLT Sbjct: 774 RTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHFQQAIMTAGTDHRTFIEISAHPLLT 833 Query: 832 HAITDTLAAAESRTRLIT-ATLQRDGDDAITFHTNLAAV-------GKKPADAVTGQLAD 883 AITDTL TR I+ TLQRD DD +TFHTNL V PA+ Sbjct: 834 QAITDTLHG----TRCISIGTLQRDADDTVTFHTNLNNVHTVHPPHTPHPAE----PHVT 885 Query: 884 IPVTPWQHTQFWV 896 IP TPWQHT+ W+ Sbjct: 886 IPSTPWQHTRHWI 898 Score = 90.5 bits (223), Expect = 2e-15 Identities = 107/451 (23%), Positives = 175/451 (38%), Gaps = 16/451 (3%) Query: 1325 PRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGA--DSVTRLA 1381 P+L +VT V E PA L G R LA EHPE+ +++DLD + R Sbjct: 1049 PKLVVVTRNAQPVAVGERANPAHAVLWGFGRTLALEHPEIWGSVIDLDASMPPELAARCI 1108 Query: 1382 GELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXX 1441 + + +D+ + +D V +R R +L R + +V Sbjct: 1109 LDEVASQDEKDREDQVVYRACLRRAPRLQRRTASAVSSVKLSSGQDTTQLVIGATGNIGP 1168 Query: 1442 VVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVA-ESLVAAA 1500 + R L GA +V R+ PS ++ L + ++ AT+ A +L Sbjct: 1169 HLIRQLAAMGATTIVAVSRN-PSTRLLELDKNLAATGTNLISVAADATDPTAMTALFDRF 1227 Query: 1501 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS 1560 L GI A LL MT + + ++ PK A LH + + + ++L FS Sbjct: 1228 GVDLPPLEGIYLAAFAGRPVLLSDMTDNDVVAMFRPKLDVASLLHRLSLKQPVKYFLLFS 1287 Query: 1561 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVA-----QALVGT 1615 S + L+GS Y SA+LD L RR GLPA + WG W + A Q + Sbjct: 1288 SISGLIGSRWLAHYTATSAFLDILGYARRLVGLPATVVAWGLWKSLADAQQDATQVSAES 1347 Query: 1616 PLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXX 1675 L P+T + V L A + R + +V +L Sbjct: 1348 GLQPMTDDVAIGALPLVMSPDAPVHSVVAAADWPLLAAAYQTRGV---LRMVDDLLPAPG 1404 Query: 1676 XXXXXXPEALKEMDPAEARQ---VVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLM 1732 E K + +A + ++ + + +A MG +D S +LG+DSLM Sbjct: 1405 EVLMQESEFRKALRTCQAERRHNMLFDHVSALVAKAMGLLPAETLDPSAGFFQLGMDSLM 1464 Query: 1733 AVRIRNTARADFGVEPPVTLILQGASLHDLT 1763 +V ++ G P +++ +++ LT Sbjct: 1465 SVTLQRALSDSLGEFLPASVVFDYPTVYSLT 1495 >tr|Q49932|Q49932_MYCLE Tax_Id=1769 SubName: Full=PksC;[Mycobacterium leprae] Length = 1446 Score = 1051 bits (2719), Expect = 0.0 Identities = 551/913 (60%), Positives = 644/913 (70%), Gaps = 32/913 (3%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R L E + +AEP+AVVGIGCR PG+V+GPDSFW L Sbjct: 1 MRTAFSRISGMTTQQRAALIEEFTKLSRIA---VAEPIAVVGIGCRFPGDVTGPDSFWDL 57 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L+DGR+A+ VPADRWDADAFYDPDP PGRMTTKW TPREA A Sbjct: 58 LIDGRNAISRVPADRWDADAFYDPDPLTPGRMTTKWGGFVSDIAGFDAAFFGITPREAAA 117 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALE+AG+PPDSL +RT ++G+ +Y + +DAY TG Sbjct: 118 MDPQQRILLEVAWEALENAGIPPDSLGNSRTGVMIGVYFNEYQSMLASSLENVDAYSGTG 177 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGP+VAVDTACSSSLVA+HLACQSLRLRE+D+ LAGGV + L P Sbjct: 178 NAHSITVGRISYLLGLRGPSVAVDTACSSSLVAVHLACQSLRLRETDLVLAGGVSITLRP 237 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD VLAVVRGSA Sbjct: 238 ETQIAISAWGLLSPHGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDLVLAVVRGSA 297 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ +D +SVNYVE+HGTGTVLGDPIEFEALAAT Sbjct: 298 VNQDGRSNGVTAPNTAAQCDVITDALRSSDVAPESVNYVESHGTGTVLGDPIEFEALAAT 357 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG +G +CALG+VKTNLGHLEAAAGI FIK LAV G IPPNLHFS+WNPAIDA Sbjct: 358 YG----RGESACALGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNLHFSQWNPAIDA 413 Query: 421 SSTRLFVPTQGAQWP-----AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGL 473 +STR FVPT+ + WP AG RRAAVSSFGL GTNAHVV+EQ + + + Sbjct: 414 ASTRFFVPTENSSWPISDGQAGPRRAAVSSFGLGGTNAHVVIEQGPELTPVTECSSNTAV 473 Query: 474 SALVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXX 533 S LVV+GKT RVAAMA LADWV+GPG + LADVAHTLNHHR+RH KF Sbjct: 474 STLVVTGKTASRVAAMAGMLADWVEGPGAEVALADVAHTLNHHRSRHAKFGTVVARDRIQ 533 Query: 534 XXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAE 593 GLRALAAG+ PGV+G QD GTVFVYSG+GSQW GMGRQLLADEP+F AA+AE Sbjct: 534 AVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGSQWAGMGRQLLADEPAFTAAVAE 593 Query: 594 LEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMG 653 LEP FV AGFSL L G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHS+G Sbjct: 594 LEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSLG 653 Query: 654 EVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAV 713 EV+AAVVAGALT A+G +V ATRSRLMA L+GQG Y QVTLA+ Sbjct: 654 EVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDYSQVTLAI 713 Query: 714 HASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTP 773 + SP Q+V+AGP E +D +I V QNR A R+ ++VA H+P +D + P +RS LAD+ P Sbjct: 714 YNSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADVAP 773 Query: 774 QPPAIPMITTTCEQ--PQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLT 831 + P IP+++TT PV DA +WA N+RNPV F QAI TAG H TF+EIS HPLLT Sbjct: 774 RTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHFQQAIMTAGTDHRTFIEISAHPLLT 833 Query: 832 HAITDTLAAAESRTRLIT-ATLQRDGDDAITFHTNLAAV-------GKKPADAVTGQLAD 883 AITDTL TR I+ TLQRD DD +TFHTNL V PA+ Sbjct: 834 QAITDTLHG----TRCISIGTLQRDADDTVTFHTNLNNVHTVHPPHTPHPAE----PHVT 885 Query: 884 IPVTPWQHTQFWV 896 IP TPWQHT+ W+ Sbjct: 886 IPSTPWQHTRHWI 898 Score = 79.3 bits (194), Expect = 5e-12 Identities = 79/290 (27%), Positives = 120/290 (41%), Gaps = 5/290 (1%) Query: 1325 PRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGA--DSVTRLA 1381 P+L +VT V E PA L G R LA EHPE+ +++DLD + R Sbjct: 1049 PKLVVVTRNAQPVAVGERANPAHAVLWGFGRTLALEHPEIWGSVIDLDASMPPELAARCI 1108 Query: 1382 GELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXX 1441 + + +D+ + +D V +R R +L R + +V Sbjct: 1109 LDEVASQDEKDREDQVVYRACLRRAPRLQRRTASAVSSVKLSSGQDTTQLVIGATGNIGP 1168 Query: 1442 VVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVA-ESLVAAA 1500 + R L GA +V R+ PS ++ L + ++ AT+ A +L Sbjct: 1169 HLIRQLAAMGATTIVAVSRN-PSTRLLELDKNLAATGTNLISVAADATDPTAMTALFDRF 1227 Query: 1501 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS 1560 L GI A LL MT + + ++ PK A LH + + + ++L FS Sbjct: 1228 GVDLPPLEGIYLAAFAGRPVLLSDMTDNDVVAMFRPKLDVASLLHRLSLKQPVKYFLLFS 1287 Query: 1561 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVAQ 1610 S + L+GS Y SA+LD L RR GLPA + WG W + AQ Sbjct: 1288 SISGLIGSRWLAHYTATSAFLDILGYARRLVGLPATVVAWGLWKSLADAQ 1337 >tr|B8ZT39|B8ZT39_MYCLB Tax_Id=561304 SubName: Full=Polyketide synthase;[Mycobacterium leprae] Length = 1540 Score = 1050 bits (2716), Expect = 0.0 Identities = 550/913 (60%), Positives = 644/913 (70%), Gaps = 32/913 (3%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M + R + M+ + R L E + +AEP+AVVGIGCR PG+V+GPDSFW L Sbjct: 1 MRTAFSRISGMTTQQRAALIEEFTKLSRIA---VAEPIAVVGIGCRFPGDVTGPDSFWDL 57 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 L+DGR+A+ VPADRWDADAFYDPDP PGRMTTKW TPREA A Sbjct: 58 LIDGRNAISRVPADRWDADAFYDPDPLTPGRMTTKWGGFVSDIAGFDAAFFGITPREAAA 117 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEVAWEALE+AG+PPDSL +RT ++G+ +Y + +DAY TG Sbjct: 118 MDPQQRILLEVAWEALENAGIPPDSLGNSRTGVMIGVYFNEYQSMLASSLENVDAYSGTG 177 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS VGRISYLLGLRGP++AVDTACSSSLVA+HLACQSLRLRE+D+ LAGGV + L P Sbjct: 178 NAHSITVGRISYLLGLRGPSLAVDTACSSSLVAVHLACQSLRLRETDLVLAGGVSITLRP 237 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC FDA ADGFVR EG GVVVLKRL DAVRDGD VLAVVRGSA Sbjct: 238 ETQIAISAWGLLSPHGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDLVLAVVRGSA 297 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ +D +SVNYVE+HGTGTVLGDPIEFEALAAT Sbjct: 298 VNQDGRSNGVTAPNTAAQCDVITDALRSSDVAPESVNYVESHGTGTVLGDPIEFEALAAT 357 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YG +G +CALG+VKTNLGHLEAAAGI FIK LAV G IPPNLHFS+WNPAIDA Sbjct: 358 YG----RGESACALGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNLHFSQWNPAIDA 413 Query: 421 SSTRLFVPTQGAQWP-----AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQ--PRSGL 473 +STR FVPT+ + WP AG RRAAVSSFGL GTNAHVV+EQ + + + Sbjct: 414 ASTRFFVPTENSSWPISDGQAGPRRAAVSSFGLGGTNAHVVIEQGPELTPVTECSSNTAV 473 Query: 474 SALVVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXX 533 S LVV+GKT RVAAMA LADWV+GPG + LADVAHTLNHHR+RH KF Sbjct: 474 STLVVTGKTASRVAAMAGMLADWVEGPGAEVALADVAHTLNHHRSRHAKFGTVVARDRIQ 533 Query: 534 XXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAE 593 GLRALAAG+ PGV+G QD GTVFVYSG+GSQW GMGRQLLADEP+F AA+AE Sbjct: 534 AVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGSQWAGMGRQLLADEPAFTAAVAE 593 Query: 594 LEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMG 653 LEP FV AGFSL L G+E+VGI++IQ L+G+QL LT LWRS+GV PD V+GHS+G Sbjct: 594 LEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSLG 653 Query: 654 EVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAV 713 EV+AAVVAGALT A+G +V ATRSRLMA L+GQG Y QVTLA+ Sbjct: 654 EVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDYSQVTLAI 713 Query: 714 HASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTP 773 + SP Q+V+AGP E +D +I V QNR A R+ ++VA H+P +D + P +RS LAD+ P Sbjct: 714 YNSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADVAP 773 Query: 774 QPPAIPMITTTCEQ--PQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLT 831 + P IP+++TT PV DA +WA N+RNPV F QAI TAG H TF+EIS HPLLT Sbjct: 774 RTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHFQQAIMTAGTDHRTFIEISAHPLLT 833 Query: 832 HAITDTLAAAESRTRLIT-ATLQRDGDDAITFHTNLAAV-------GKKPADAVTGQLAD 883 AITDTL TR I+ TLQRD DD +TFHTNL V PA+ Sbjct: 834 QAITDTLHG----TRCISIGTLQRDADDTVTFHTNLNNVHTVHPPHTPHPAE----PHVT 885 Query: 884 IPVTPWQHTQFWV 896 IP TPWQHT+ W+ Sbjct: 886 IPSTPWQHTRHWI 898 Score = 90.5 bits (223), Expect = 2e-15 Identities = 107/451 (23%), Positives = 175/451 (38%), Gaps = 16/451 (3%) Query: 1325 PRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGA--DSVTRLA 1381 P+L +VT V E PA L G R LA EHPE+ +++DLD + R Sbjct: 1049 PKLVVVTRNAQPVAVGERANPAHAVLWGFGRTLALEHPEIWGSVIDLDASMPPELAARCI 1108 Query: 1382 GELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXXXX 1441 + + +D+ + +D V +R R +L R + +V Sbjct: 1109 LDEVASQDEKDREDQVVYRACLRRAPRLQRRTASAVSSVKLSSGQDTTQLVIGATGNIGP 1168 Query: 1442 VVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRAEVVVVCGDSATEGVA-ESLVAAA 1500 + R L GA +V R+ PS ++ L + ++ AT+ A +L Sbjct: 1169 HLIRQLAAMGATTIVAVSRN-PSTRLLELDKNLAATGTNLISVAADATDPTAMTALFDRF 1227 Query: 1501 EDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFS 1560 L GI A LL MT + + ++ PK A LH + + + ++L FS Sbjct: 1228 GVDLPPLEGIYLAAFAGRPVLLSDMTDNDVVAMFRPKLDVASLLHRLSLKQPVKYFLLFS 1287 Query: 1561 STASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVA-----QALVGT 1615 S + L+GS Y SA+LD L RR GLPA + WG W + A Q + Sbjct: 1288 SISGLIGSRWLAHYTATSAFLDILGYARRLVGLPATVVAWGLWKSLADAQQDATQVSAES 1347 Query: 1616 PLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXX 1675 L P+T + V L A + R + +V +L Sbjct: 1348 GLQPMTDDVAIGALPLVMSPDAPVHSVVAAADWPLLAAAYQTRGV---LRMVDDLLPAPG 1404 Query: 1676 XXXXXXPEALKEMDPAEARQ---VVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLM 1732 E K + +A + ++ + + +A MG +D S +LG+DSLM Sbjct: 1405 EVLMQESEFRKALRTCQAERRHNMLFDHVSALVAKAMGLLPAETLDPSAGFFQLGMDSLM 1464 Query: 1733 AVRIRNTARADFGVEPPVTLILQGASLHDLT 1763 +V ++ G P +++ +++ LT Sbjct: 1465 SVTLQRALSDSLGEFLPASVVFDYPTVYSLT 1495 >tr|B2HIN0|B2HIN0_MYCMM Tax_Id=216594 (ppsB)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsB;[Mycobacterium marinum] Length = 1524 Score = 1036 bits (2679), Expect = 0.0 Identities = 531/916 (57%), Positives = 638/916 (69%), Gaps = 16/916 (1%) Query: 1 MTSLAERAAQMSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQL 60 M S+ R + M+ + R L+ E RA T AEPVAVVGIGCR PGNV+GPDSFW L Sbjct: 1 MRSVYSRISSMTAQQRAALSEEFSRASR---TTTAEPVAVVGIGCRFPGNVTGPDSFWDL 57 Query: 61 LVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVA 120 LV+G +A+ +PA+RWDAD +Y PDP PG MTTKW TPREA + Sbjct: 58 LVEGGNAISGIPAERWDADDYYHPDPLTPGHMTTKWGAFVADIAGFDAEFFGITPREAAS 117 Query: 121 MDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTG 180 MDPQQR+LLEV WEALEHAG+P +SL+GTRTA +MG+ +Y + R +DAY TG Sbjct: 118 MDPQQRMLLEVTWEALEHAGIPTESLAGTRTAVMMGVYFNEYQSMLASSRENVDAYTGTG 177 Query: 181 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSP 240 N HS GRISYLLGLRGPA A+DTACSSSL A+HLACQSLRLRE+D+ALAGGV L P Sbjct: 178 NSHSITAGRISYLLGLRGPAAAIDTACSSSLSAIHLACQSLRLRETDLALAGGVSATLRP 237 Query: 241 FTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSA 300 T IA+S W LSP GRC TFDA ADGFVR EG GVVVLKRL DA+RD D++LAVVRGSA Sbjct: 238 ETQIAISAWGLLSPEGRCATFDAAADGFVRGEGAGVVVLKRLTDALRDQDQILAVVRGSA 297 Query: 301 INQDGRSNGMTAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAAT 360 +NQDGRSNG+TAPN AAQ DVI AL+ AD +SV+YVETHGTGT LGDPIEFEALAAT Sbjct: 298 VNQDGRSNGITAPNTAAQCDVIADALRSADVAPESVHYVETHGTGTQLGDPIEFEALAAT 357 Query: 361 YGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDA 420 YGL K + DSCALG+VKTN+GHLEAA+G+ FIKA LAV HG IPPNLHFS+WNPAIDA Sbjct: 358 YGLIKGQDGDSCALGAVKTNIGHLEAASGVAGFIKAVLAVQHGQIPPNLHFSQWNPAIDA 417 Query: 421 SSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQPRSG--LSAL 476 +STRLFVP WP +G RRAAVSSFGL GTNAH ++EQ + + ++ L Sbjct: 418 ASTRLFVPLDNIAWPSDSGPRRAAVSSFGLGGTNAHAIVEQGPELSPAGRRGTDDEVTTL 477 Query: 477 VVSGKTPQRVAAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXE 536 VV+GKTP RVAA A LADW++GPG + LADVAHTLNHHR+R +F Sbjct: 478 VVAGKTPARVAATAGMLADWMEGPGAEVALADVAHTLNHHRSRQARFGTVVARERAQAVA 537 Query: 537 GLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEP 596 GLRALAA Q PGV+ D +PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP Sbjct: 538 GLRALAANQHAPGVVNPADAPPEPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEP 597 Query: 597 DFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVS 656 F+A+AGFSL L G E+VGI++IQ L+G+QL LT LWRS+G+ PD V+GHSMGEV+ Sbjct: 598 VFLAEAGFSLHDVLANGTELVGIEQIQLGLIGMQLTLTELWRSYGIQPDLVIGHSMGEVA 657 Query: 657 AAVVAGALTPADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHAS 716 AAVVAGALTPA+G +V A RSRLMA L+GQG YPQVTL ++ S Sbjct: 658 AAVVAGALTPAEGLRVTAVRSRLMAPLSGQGGMALLGLDASQTEALIADYPQVTLGIYNS 717 Query: 717 PHQSVVAGPPESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPP 776 P Q+V++GP + +D +I V ++R A R+ ++VA H+P +D + P +RS LADL P+ P Sbjct: 718 PRQTVISGPTDQIDELITVVRARDRFATRVNIEVAPHNPAMDALQPQMRSELADLAPRTP 777 Query: 777 AIPMITTT------CEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLL 830 IP+I+TT + P DA++WA N+RNPV F QAIT A H F+EIS HPLL Sbjct: 778 TIPIISTTYADLGSARESGPTFDAEHWAINMRNPVHFQQAITAAATDKHNFIEISAHPLL 837 Query: 831 THAITDTLAAAESRTR-LITATLQRDGDDAITFHTNLAAVGKKPADA--VTGQLADIPVT 887 T AI +TL + ++ TLQRD DD I F TNL V P IP T Sbjct: 838 TQAILETLHTVQPGSKHTCLGTLQRDSDDTIVFRTNLNTVRTAPPQTPHPPEPHPQIPTT 897 Query: 888 PWQHTQFWVEDRSGIS 903 PW HT W+++ + S Sbjct: 898 PWHHTHHWIDNAASSS 913 Score = 127 bits (318), Expect = 2e-26 Identities = 120/475 (25%), Positives = 199/475 (41%), Gaps = 20/475 (4%) Query: 1321 HGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTR 1379 +G +L + T + +P P+ G L GL R + EHPE+ ++D D + Sbjct: 1040 NGSPAKLLIATRNAQPIAEGDPANPSHGVLWGLGRTITLEHPEIWGAIIDFDNSVPAQV- 1098 Query: 1380 LAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXX 1439 +A ++ D + +D V +R G R+V +L R L +P + GAS +V Sbjct: 1099 VARQVLDEADATDSEDQVVYRSGVRHVPRLRRHSLAAQPV---ALDAGASQLVIGATGNI 1155 Query: 1440 XXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRA-EVVVVCGDSATEGVAESLVA 1498 + L + GA +V R+ P +K+ L + +V+ D+ E +L Sbjct: 1156 GPHLINQLAEMGAKTIVAVSRN-PGQRLQKLAESLAAEGVNLVIAAADATDEAAMTALFD 1214 Query: 1499 AAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLG 1558 L GI A LL MT D + ++APK A LH + + ++ Sbjct: 1215 RFGADLPPLEGIYLAAFAGQPVLLTEMTNDDVTAMFAPKLDAAALLHRLSLKVPVRHFVL 1274 Query: 1559 FSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPW-----SEVGVAQALV 1613 FSS + L+GS Y S +LD L RR GLPA T+NWG W +E +Q + Sbjct: 1275 FSSISGLIGSRWLAHYTATSGYLDALAYARRVMGLPATTVNWGLWKSLADAEHDASQVSL 1334 Query: 1614 GTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLV--VQELX 1671 G+ L P+ + G V + +D L+A R G +V V + Sbjct: 1335 GSGLVPMQDDVAIGALPLVMSQAAGVHSVV-VAADWPLLA-AAYRTRGSLRIVDDVLPVS 1392 Query: 1672 XXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSL 1731 AL+ P ++ +++ A VMG ++D S +LG+DSL Sbjct: 1393 DETTVLESEFRVALRNCAPERRHDMLHDQVAMLAANVMGLHAGESLDPSTGFFQLGMDSL 1452 Query: 1732 MAVRIRNTARADFGVEPPVTLILQGASLHDLT---VDVIRQLDLAGDEQTHEHVD 1783 M+V ++ G P +++ +++ LT ++ +L+ DE T + D Sbjct: 1453 MSVTLQRALSDSLGEFLPPSVVFDYPTVYSLTDYLATILPELE-TDDESTADVYD 1506 >tr|A0PQ38|A0PQ38_MYCUA Tax_Id=362242 (ppsB)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsB;[Mycobacterium ulcerans] Length = 1514 Score = 1027 bits (2655), Expect = 0.0 Identities = 526/906 (58%), Positives = 633/906 (69%), Gaps = 16/906 (1%) Query: 11 MSPKAREVLARELVRAGTAFPTDIAEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDE 70 M+ + R L+ E RA T AEPVAVVGIGCR PGNV+GPDSFW LLV+G +A+ Sbjct: 1 MTAQQRAALSEEFSRASR---TTTAEPVAVVGIGCRFPGNVTGPDSFWDLLVEGGNAISG 57 Query: 71 VPADRWDADAFYDPDPRAPGRMTTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLE 130 +PA+RWDAD +Y PDP PG MTTKW TPREA +MDPQQR+LLE Sbjct: 58 IPAERWDADDYYHPDPLTPGHMTTKWGAFVADIAGFDAEFFGITPREAASMDPQQRMLLE 117 Query: 131 VAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRI 190 V WEALEHAG+P +SL+GTRTA +MG+ +Y + R +DAY TGN HS GRI Sbjct: 118 VTWEALEHAGIPTESLAGTRTAVMMGVYFNEYQSMLASSRENVDAYTGTGNSHSITAGRI 177 Query: 191 SYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWS 250 SYLLGLRGPA A+DTACSSSL A+HLACQSLRLRE+D+ALAGGV L P T IA+S W Sbjct: 178 SYLLGLRGPAAAIDTACSSSLSAIHLACQSLRLRETDLALAGGVSATLRPETQIAISAWG 237 Query: 251 ALSPTGRCKTFDALADGFVRSEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGM 310 LSP GRC TFDA ADGFVR EG GVVVLKRL DA+RD +++LAVVRGSA+NQDGRSNG+ Sbjct: 238 LLSPEGRCATFDAAADGFVRGEGAGVVVLKRLTDALRDQNQILAVVRGSAVNQDGRSNGI 297 Query: 311 TAPNAAAQRDVIGTALKLADATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGAD 370 TAPN AAQ DVI AL+ AD +SV+YVETHGTGT LGDPIEFEALAATYGL K + Sbjct: 298 TAPNTAAQCDVIADALRSADVAPESVHYVETHGTGTQLGDPIEFEALAATYGLIKGQDGY 357 Query: 371 SCALGSVKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQ 430 SCALG+VKTN+GHLEAA+G+ FIKA LAV HG IPPNLHFS+WNPAIDA+STRLFVP Sbjct: 358 SCALGAVKTNIGHLEAASGVAGFIKAVLAVQHGQIPPNLHFSQWNPAIDAASTRLFVPLD 417 Query: 431 GAQWP--AGLRRAAVSSFGLSGTNAHVVLEQXXXXXXXDQPRSG--LSALVVSGKTPQRV 486 WP +G RRAAVSSFGL GTNAH ++EQ + + ++ LVV+GKTP RV Sbjct: 418 NIAWPSDSGPRRAAVSSFGLGGTNAHAIVEQGPELSPAGRRGTDDEVTTLVVAGKTPARV 477 Query: 487 AAMASALADWVDGPGGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQP 546 AA A LADW++GPG + LADVAHTLNHHR+R +F GLRALAA Q Sbjct: 478 AATAGMLADWMEGPGAEVALADVAHTLNHHRSRQARFGTVVARERAQAVAGLRALAANQH 537 Query: 547 GPGVLGCQDVQNQPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSL 606 PGV+ D +PGTVFVYSG+GSQW GMGRQLLADEP+FAAA+AELEP F+A+AGFSL Sbjct: 538 APGVVNPADAPPEPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFLAEAGFSL 597 Query: 607 QQTLTEGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTP 666 L G E+VGI++IQ L+G+QL LT LWRS+G+ PD V+GHSMGEV+AAVVAGALTP Sbjct: 598 HDVLANGTELVGIEQIQLGLIGMQLTLTELWRSYGIQPDLVIGHSMGEVAAAVVAGALTP 657 Query: 667 ADGFKVIATRSRLMARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPP 726 A+G +V A RSRLMA L+GQG YPQVTL ++ SP Q+V++GP Sbjct: 658 AEGLRVTAVRSRLMAPLSGQGGMALLGLDASQTEALIADYPQVTLGIYNSPRQTVISGPT 717 Query: 727 ESVDAVIAAVAGQNRLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTT-- 784 + +D +I V ++R A R+ ++VA H+P +D + P +RS LADL P+ P IP+I+TT Sbjct: 718 DQIDELITVVRARDRFATRVNIEVAPHNPAMDALQPQMRSELADLAPRTPTIPIISTTYA 777 Query: 785 ----CEQPQPVLDADYWAANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAA 840 + P DA++WA N+RNPV F QAIT A H F+EIS HPLLT AI +TL Sbjct: 778 DLGAARESGPTFDAEHWAINMRNPVHFQQAITAAATDKHNFIEISAHPLLTQAILETLHT 837 Query: 841 AESRTRLIT-ATLQRDGDDAITFHTNLAAVGKKPADA--VTGQLADIPVTPWQHTQFWVE 897 + ++ + TLQRD DD I F TNL V P IP TPW HT W++ Sbjct: 838 VQPGSKYTSLGTLQRDSDDTIVFRTNLNTVRTAPPQTPHPPEPHPQIPTTPWHHTHHWID 897 Query: 898 DRSGIS 903 + + S Sbjct: 898 NAASSS 903 Score = 125 bits (315), Expect = 4e-26 Identities = 120/475 (25%), Positives = 198/475 (41%), Gaps = 20/475 (4%) Query: 1321 HGRAPRLWLVTEGGL-VVHDEPGRPAIGALQGLVRVLAYEHPELRATLVDLDTGADSVTR 1379 +G +L + T + +P P+ G L GL R + EHPE+ ++D D + Sbjct: 1030 NGSPAKLLIATRNAQPIAEGDPANPSHGVLWGLGRTITLEHPEIWCAIIDFDNSVPAQV- 1088 Query: 1380 LAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPVIRPGASYIVTXXXXXX 1439 +A ++ D + +D V +R G R+V +L R L +P + GAS +V Sbjct: 1089 VARQVLDEADATDSEDQVVYRSGVRHVPRLRRHSLAAQPV---ALDAGASQLVIGATGNI 1145 Query: 1440 XXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELESRA-EVVVVCGDSATEGVAESLVA 1498 + L + GA +V R+ P +K+ L + +V+ D+ E +L Sbjct: 1146 GPHLINQLAEMGAKTIVAVSRN-PGQRLQKLAESLAAEGVNLVIAAADATDEAAMTALFD 1204 Query: 1499 AAEDQQRQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLG 1558 L GI A LL MT D + ++APK A LH + + ++ Sbjct: 1205 RFGADLPPLEGIYLAAFAGQPVLLTEMTNDDVTAMFAPKLDAAALLHRLSLKVPVRHFVL 1264 Query: 1559 FSSTASLLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPW-----SEVGVAQALV 1613 FSS + L+GS Y S +LD L RR GLPA T+NWG W +E +Q + Sbjct: 1265 FSSISGLIGSRWLAHYTATSGYLDALAYARRVMGLPATTVNWGLWKSLADAEHDASQVSL 1324 Query: 1614 GTPLDPITPAEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLV--VQELX 1671 G+ L P+ + G V + +D L+A R G +V V + Sbjct: 1325 GSGLVPMQDDVAIGALPLVMSQAAGVHSVV-VAADWPLLA-AAYRTRGSLRIVDDVLPVS 1382 Query: 1672 XXXXXXXXXXPEALKEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSL 1731 AL+ P ++ +++ A VMG + D S +LG+DSL Sbjct: 1383 DETTVLESEFRVALRNCAPERRHDMLHDQVAMLAANVMGLHAGESPDPSTGFFQLGMDSL 1442 Query: 1732 MAVRIRNTARADFGVEPPVTLILQGASLHDLT---VDVIRQLDLAGDEQTHEHVD 1783 M+V ++ G P +++ +++ LT ++ +L+ DE T + D Sbjct: 1443 MSVTLQRALSDSLGEFLPPSVVFDYPTVYSLTDYLATILPELE-TDDESTADIYD 1496 >tr|Q9Z5K6|Q9Z5K6_MYCLE Tax_Id=1769 (MLCB12.02c)SubName: Full=Polyketide synthase; SubName: Full=Putative polyketide synthase;[Mycobacterium leprae] Length = 1871 Score = 1012 bits (2617), Expect = 0.0 Identities = 703/1821 (38%), Positives = 932/1821 (51%), Gaps = 157/1821 (8%) Query: 34 IAEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMT 93 + EP+AV+G+GCR PG +SGP++ WQ L D R ++ +VP +RW+ P+ +A T Sbjct: 100 LEEPIAVIGMGCRFPGGISGPEALWQFLCDRRSSIGQVPNERWELFDDGSPEVKALLART 159 Query: 94 TKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAA 153 T+W +P EA MDPQQR+LLEVAWEALEHAG+ +SL ++T Sbjct: 160 TRWGSFLEDIDAFDSEFFEISPSEADKMDPQQRLLLEVAWEALEHAGISSNSLRRSQTGV 219 Query: 154 VMGLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVA 213 G +Y + +++D + +TG S R+SY L LRGP+VAVDTACSSSLVA Sbjct: 220 FAGSCLSEYGAIASTDLSQVDGWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVA 279 Query: 214 LHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEG 273 +HLACQSLR ++++A+A GV L+LSP + ALSPTG C+ FDA ADGFVR EG Sbjct: 280 IHLACQSLRTADANLAIAAGVNLLLSPAVFRGFDQVGALSPTGCCRAFDAAADGFVRGEG 339 Query: 274 CGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADATA 333 GVVVLKRL DA RDGDRVLA++RGSA+NQDGRSNG+ APN AAQ V+ TA A Sbjct: 340 AGVVVLKRLTDAQRDGDRVLAIIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAYANAAMPP 399 Query: 334 DSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSF 393 +++YVETHGTGT+LGDPIE AL A G G+ + + +G+VKTNLGHLEAAAGI F Sbjct: 400 TAIDYVETHGTGTLLGDPIEARALGAVLGRGRAEDS-PLLIGAVKTNLGHLEAAAGIAGF 458 Query: 394 IKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGT 451 IK LAV G IPPN F N I + R+ V + +WP LRRAAVSSFG GT Sbjct: 459 IKTVLAVQRGQIPPNQRFESPNLHIPFAELRMKVVDKHMEWPDTGHLRRAAVSSFGFGGT 518 Query: 452 NAHVVLEQXXXXXXXDQ--PRSGLSALVVSGKTPQRVAAMASALADWVDGPGGQTPLADV 509 NAHVV+EQ + + +S LVV+GKT RVAAMA LADWV+GPG + LADV Sbjct: 519 NAHVVIEQGPELTPVTECSSNTAVSTLVVTGKTASRVAAMAGMLADWVEGPGAEVALADV 578 Query: 510 AHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQ 569 AHTLNHHR+RH KF GLRALAAG+ PGV+G QD GTVFVYSG+ Sbjct: 579 AHTLNHHRSRHAKFGTVVARDRIQAVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGR 638 Query: 570 GSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGI 629 GSQW GMGRQLLADEP+F AA+AELEP FV AGFSL L G+E+VGI++IQ L+G+ Sbjct: 639 GSQWAGMGRQLLADEPAFTAAVAELEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGM 698 Query: 630 QLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXX 689 QL LT LWRS+GV PD V+GHS+GEV+AAVVAGALT A+G +V ATRSRLMA L+GQG Sbjct: 699 QLTLTELWRSYGVQPDLVIGHSLGEVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGM 758 Query: 690 XXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVD 749 Y QVTLA++ SP Q+V+AGP E +D +I V QNR A R+ ++ Sbjct: 759 ALLELDAVETEALIVDYSQVTLAIYNSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIE 818 Query: 750 VASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ--PQPVLDADYWAANLRNPVRF 807 VA H+P +D + P +RS LAD+ P+ P IP+++TT PV DA +WA N+RNPV F Sbjct: 819 VAPHNPAMDALQPQMRSELADVAPRTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHF 878 Query: 808 HQAITTAGAQHHTFVEISPHPLLTHAITDTLAAAESRTRLIT-ATLQRDGDDAITFHTNL 866 QAI TAG H TF+EIS HPLLT AITDTL TR I+ TLQRD DD +TFHTNL Sbjct: 879 QQAIMTAGTDHRTFIEISAHPLLTQAITDTLHG----TRCISIGTLQRDADDTVTFHTNL 934 Query: 867 AAV-------GKKPADAVTGQLADIPVTPWQHTQFWVEDRSGISELVAA---HPLLGVHI 916 V PA+ IP TPWQHT+ W+ + ++ + A LLG H Sbjct: 935 NNVHTVHPPHTPHPAE----PHVTIPSTPWQHTRHWIPRKRSVNSIGLAPQVGTLLGQHT 990 Query: 917 EVPSG--HDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVDALS 974 V SG H+WQA + +A P+ G H+V G ++P +L L Sbjct: 991 AV-SGILPIHLWQARLAPQAKPYRGWHRVHGVEVVPASIVLRTILCAAA---ELGYSTLF 1046 Query: 975 INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSAS-----GWRRHAVAK-----A 1024 + E +L QV D I + S A+ W RH A+ A Sbjct: 1047 EIRFEQPIFANLPRLIQVVV-------DNQLISLASSPATETPQHRWTRHVTAQLSSASA 1099 Query: 1025 ETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVE-- 1082 ++ PS P ++ + D+ +LL G + P ++ ++ S Sbjct: 1100 RSAVPSDHP--DQINGHLEVISDPIPDVASLLALCGVDGLPFEWSVKSWAKKTQQSTSRT 1157 Query: 1083 TEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSNP 1142 EI D P I P + A L A V +F Y+P S + +V+ Sbjct: 1158 VEIEFPDTLP---DGAIAPLLDAAILIPALADVTETQF-------YVPASIK--QVWLGD 1205 Query: 1143 GRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEIND------IYLRRVERRSVPLPL 1196 C GA L R DD V V + D +R + R++ L Sbjct: 1206 TATGPC----------GAVTLNRTACDDDGITVDVTVADGSGVPLALMRSLRYRALDLDN 1255 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPG-----SWLVLTDAKSNADEFVARWSSPQRRVITADL 1251 AQ+ + T +VE + DA W TD + + S A + Sbjct: 1256 AQQDYSTVFVESHVDAL--TDARNFVHAIDWQPRTDLDCSNTPVASSGS-------VAVI 1306 Query: 1252 GDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVWQIST 1311 GD G P D R T +IS Sbjct: 1307 GDARAGFGLLLKEAGYTLAAPADGVSEVRYVVYVADPHPATTAETDVDFAVRITA-EISD 1365 Query: 1312 VVRAIVGTWHGRAPRLWLVTEGGLVVHDEPGRPAI--GALQGLVRVLAYEHPELRATLVD 1369 +VRA+ G+ LW+VT G V++ A+ L G V+A EHPE+ LVD Sbjct: 1366 LVRALAKREPGKPVALWIVTRG---VYESVASSALRQSFLWGFGGVIAAEHPEMWGGLVD 1422 Query: 1370 LDTGA------DSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPV 1423 L A D + + L+S P +V RDG V + EP R + Sbjct: 1423 LAASALGADRDDILDQFGPTLASLLQTPT-RSIVVLRDG--VVLAPTLVPIRSEPVRKSL 1479 Query: 1424 -IRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES--RAEV 1480 + +Y++T ++A WL D GA R+VL GR+ + L L++ R ++ Sbjct: 1480 QCKSDGAYLITGGMGALGLLMADWLADRGARRLVLMGRTPLPPRRDWELDTLDAGLRQKI 1539 Query: 1481 VVVCG----DSATEGVA---------ESLVAAAE-DQQRQLRGIVHGAAVIDDSLLFSMT 1526 +C E VA ++L+A + D +RGI+H A V +D L+ +MT Sbjct: 1540 DAICALEMRGVTVEAVAVDVGHHDDVQALLAKRDRDGAAPIRGIIHAAGVTNDQLVTNMT 1599 Query: 1527 KDSLERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVA 1586 D + +V PK AG LH+A +D++ SS A + G PGQ +YA A+++LD L Sbjct: 1600 DDPVRQVMWPKIAGCQVLHEAFPPGSVDFFYLTSSAAGIFGIPGQGSYAAANSYLDALAR 1659 Query: 1587 WRRAAGLPAATINWGPWSEVGVA--QALVGTPLD-----PITPAEGVVXXXXXXXXXRGR 1639 RR G +I+W W +G A +V L ITP+E + Sbjct: 1660 TRRQQGCHTMSIDWVAWRGLGFAANAQIVSDELQRMGSRDITPSEAFTAWEYVDAYDVAQ 1719 Query: 1640 TGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTE 1699 + P R+ G +M+ AE R+ + Sbjct: 1720 A-----------VVLPVPRSYG-------SAGSTAGDSYLVPARNWSQMEAAEVRKELES 1761 Query: 1700 RLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASL 1759 L T IAA + A+ + +D P ELGL+SLMA+ IR A G+E ++ ++ Sbjct: 1762 GLRTIIAAELRVAE-AELDTDRPFAELGLNSLMAMAIRREAEQFIGIELSAIMLFNHPTV 1820 Query: 1760 ----HDLTVDVIRQLDLAGDE 1776 LT V Q D GDE Sbjct: 1821 ALLAAYLTKVVAPQHDSQGDE 1841 >tr|B8ZT40|B8ZT40_MYCLB Tax_Id=561304 SubName: Full=Polyketide synthase;[Mycobacterium leprae] Length = 1871 Score = 1012 bits (2617), Expect = 0.0 Identities = 703/1821 (38%), Positives = 932/1821 (51%), Gaps = 157/1821 (8%) Query: 34 IAEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMT 93 + EP+AV+G+GCR PG +SGP++ WQ L D R ++ +VP +RW+ P+ +A T Sbjct: 100 LEEPIAVIGMGCRFPGGISGPEALWQFLCDRRSSIGQVPNERWELFDDGSPEVKALLART 159 Query: 94 TKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAA 153 T+W +P EA MDPQQR+LLEVAWEALEHAG+ +SL ++T Sbjct: 160 TRWGSFLEDIDAFDSEFFEISPSEADKMDPQQRLLLEVAWEALEHAGISSNSLRRSQTGV 219 Query: 154 VMGLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVA 213 G +Y + +++D + +TG S R+SY L LRGP+VAVDTACSSSLVA Sbjct: 220 FAGSCLSEYGAIASTDLSQVDGWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVA 279 Query: 214 LHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEG 273 +HLACQSLR ++++A+A GV L+LSP + ALSPTG C+ FDA ADGFVR EG Sbjct: 280 IHLACQSLRTADANLAIAAGVNLLLSPAVFRGFDQVGALSPTGCCRAFDAAADGFVRGEG 339 Query: 274 CGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADATA 333 GVVVLKRL DA RDGDRVLA++RGSA+NQDGRSNG+ APN AAQ V+ TA A Sbjct: 340 AGVVVLKRLTDAQRDGDRVLAIIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAYANAAMPP 399 Query: 334 DSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSF 393 +++YVETHGTGT+LGDPIE AL A G G+ + + +G+VKTNLGHLEAAAGI F Sbjct: 400 TAIDYVETHGTGTLLGDPIEARALGAVLGRGRAEDS-PLLIGAVKTNLGHLEAAAGIAGF 458 Query: 394 IKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWP--AGLRRAAVSSFGLSGT 451 IK LAV G IPPN F N I + R+ V + +WP LRRAAVSSFG GT Sbjct: 459 IKTVLAVQRGQIPPNQRFESPNLHIPFAELRMKVVDKHMEWPDTGHLRRAAVSSFGFGGT 518 Query: 452 NAHVVLEQXXXXXXXDQ--PRSGLSALVVSGKTPQRVAAMASALADWVDGPGGQTPLADV 509 NAHVV+EQ + + +S LVV+GKT RVAAMA LADWV+GPG + LADV Sbjct: 519 NAHVVIEQGPELTPVTECSSNTAVSTLVVTGKTASRVAAMAGMLADWVEGPGAEVALADV 578 Query: 510 AHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQ 569 AHTLNHHR+RH KF GLRALAAG+ PGV+G QD GTVFVYSG+ Sbjct: 579 AHTLNHHRSRHAKFGTVVARDRIQAVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGR 638 Query: 570 GSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGI 629 GSQW GMGRQLLADEP+F AA+AELEP FV AGFSL L G+E+VGI++IQ L+G+ Sbjct: 639 GSQWAGMGRQLLADEPAFTAAVAELEPVFVVHAGFSLHDVLANGKELVGIEQIQLGLIGM 698 Query: 630 QLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXX 689 QL LT LWRS+GV PD V+GHS+GEV+AAVVAGALT A+G +V ATRSRLMA L+GQG Sbjct: 699 QLTLTELWRSYGVQPDLVIGHSLGEVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGM 758 Query: 690 XXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVD 749 Y QVTLA++ SP Q+V+AGP E +D +I V QNR A R+ ++ Sbjct: 759 ALLELDAVETEALIVDYSQVTLAIYNSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIE 818 Query: 750 VASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ--PQPVLDADYWAANLRNPVRF 807 VA H+P +D + P +RS LAD+ P+ P IP+++TT PV DA +WA N+RNPV F Sbjct: 819 VAPHNPAMDALQPQMRSELADVAPRTPTIPILSTTYADLGSCPVFDAQHWATNMRNPVHF 878 Query: 808 HQAITTAGAQHHTFVEISPHPLLTHAITDTLAAAESRTRLIT-ATLQRDGDDAITFHTNL 866 QAI TAG H TF+EIS HPLLT AITDTL TR I+ TLQRD DD +TFHTNL Sbjct: 879 QQAIMTAGTDHRTFIEISAHPLLTQAITDTLHG----TRCISIGTLQRDADDTVTFHTNL 934 Query: 867 AAV-------GKKPADAVTGQLADIPVTPWQHTQFWVEDRSGISELVAA---HPLLGVHI 916 V PA+ IP TPWQHT+ W+ + ++ + A LLG H Sbjct: 935 NNVHTVHPPHTPHPAE----PHVTIPSTPWQHTRHWIPRKRSVNSIGLAPQVGTLLGQHT 990 Query: 917 EVPSG--HDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVDALS 974 V SG H+WQA + +A P+ G H+V G ++P +L L Sbjct: 991 AV-SGILPIHLWQARLAPQAKPYRGWHRVHGVEVVPASIVLRTILCAAA---ELGYSTLF 1046 Query: 975 INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSAS-----GWRRHAVAK-----A 1024 + E +L QV D I + S A+ W RH A+ A Sbjct: 1047 EIRFEQPIFANLPRLIQVVV-------DNQLISLASSPATETPQHRWTRHVTAQLSSASA 1099 Query: 1025 ETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSVE-- 1082 ++ PS P ++ + D+ +LL G + P ++ ++ S Sbjct: 1100 RSAVPSDHP--DQINGHLEVISDPIPDVASLLALCGVDGLPFEWSVKSWAKKTQQSTSRT 1157 Query: 1083 TEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSNP 1142 EI D P I P + A L A V +F Y+P S + +V+ Sbjct: 1158 VEIEFPDTLP---DGAIAPLLDAAILIPALADVTETQF-------YVPASIK--QVWLGD 1205 Query: 1143 GRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEIND------IYLRRVERRSVPLPL 1196 C GA L R DD V V + D +R + R++ L Sbjct: 1206 TATGPC----------GAVTLNRTACDDDGITVDVTVADGSGVPLALMRSLRYRALDLDN 1255 Query: 1197 AQKIFDTEWVEKSIAGADQPDAPG-----SWLVLTDAKSNADEFVARWSSPQRRVITADL 1251 AQ+ + T +VE + DA W TD + + S A + Sbjct: 1256 AQQDYSTVFVESHVDAL--TDARNFVHAIDWQPRTDLDCSNTPVASSGS-------VAVI 1306 Query: 1252 GDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVWQIST 1311 GD G P D R T +IS Sbjct: 1307 GDARAGFGLLLKEAGYTLAAPADGVSEVRYVVYVADPHPATTAETDVDFAVRITA-EISD 1365 Query: 1312 VVRAIVGTWHGRAPRLWLVTEGGLVVHDEPGRPAI--GALQGLVRVLAYEHPELRATLVD 1369 +VRA+ G+ LW+VT G V++ A+ L G V+A EHPE+ LVD Sbjct: 1366 LVRALAKREPGKPVALWIVTRG---VYESVASSALRQSFLWGFGGVIAAEHPEMWGGLVD 1422 Query: 1370 LDTGA------DSVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPEPQRDPV 1423 L A D + + L+S P +V RDG V + EP R + Sbjct: 1423 LAASALGADRDDILDQFGPTLASLLQTPT-RSIVVLRDG--VVLAPTLVPIRSEPVRKSL 1479 Query: 1424 -IRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSEPSDEQRKVLAELES--RAEV 1480 + +Y++T ++A WL D GA R+VL GR+ + L L++ R ++ Sbjct: 1480 QCKSDGAYLITGGMGALGLLMADWLADRGARRLVLMGRTPLPPRRDWELDTLDAGLRQKI 1539 Query: 1481 VVVCG----DSATEGVA---------ESLVAAAE-DQQRQLRGIVHGAAVIDDSLLFSMT 1526 +C E VA ++L+A + D +RGI+H A V +D L+ +MT Sbjct: 1540 DAICALEMRGVTVEAVAVDVGHHDDVQALLAKRDRDGAAPIRGIIHAAGVTNDQLVTNMT 1599 Query: 1527 KDSLERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVA 1586 D + +V PK AG LH+A +D++ SS A + G PGQ +YA A+++LD L Sbjct: 1600 DDPVRQVMWPKIAGCQVLHEAFPPGSVDFFYLTSSAAGIFGIPGQGSYAAANSYLDALAR 1659 Query: 1587 WRRAAGLPAATINWGPWSEVGVA--QALVGTPLD-----PITPAEGVVXXXXXXXXXRGR 1639 RR G +I+W W +G A +V L ITP+E + Sbjct: 1660 TRRQQGCHTMSIDWVAWRGLGFAANAQIVSDELQRMGSRDITPSEAFTAWEYVDAYDVAQ 1719 Query: 1640 TGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEARQVVTE 1699 + P R+ G +M+ AE R+ + Sbjct: 1720 A-----------VVLPVPRSYG-------SAGSTAGDSYLVPARNWSQMEAAEVRKELES 1761 Query: 1700 RLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASL 1759 L T IAA + A+ + +D P ELGL+SLMA+ IR A G+E ++ ++ Sbjct: 1762 GLRTIIAAELRVAE-AELDTDRPFAELGLNSLMAMAIRREAEQFIGIELSAIMLFNHPTV 1820 Query: 1760 ----HDLTVDVIRQLDLAGDE 1776 LT V Q D GDE Sbjct: 1821 ALLAAYLTKVVAPQHDSQGDE 1841 >sp|Q10977|PPSA_MYCTU Tax_Id=1773 (ppsA)RecName: Full=Phenolpthiocerol synthesis polyketide synthase ppsA;[Mycobacterium tuberculosis] Length = 1876 Score = 1003 bits (2592), Expect = 0.0 Identities = 701/1844 (38%), Positives = 926/1844 (50%), Gaps = 201/1844 (10%) Query: 36 EPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTK 95 EP+AVVG+GCR PG +S P++ W L + R ++ +VP RW P+ A TT+ Sbjct: 102 EPIAVVGMGCRFPGGISCPEALWDFLCERRSSISQVPPQRWQPFEGGPPEVAAALARTTR 161 Query: 96 WXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVM 155 W +P EA MDPQQR+LLEVAWEALEHAG+PP +L + T Sbjct: 162 WGSFLPDIDAFDAEFFEISPSEADKMDPQQRLLLEVAWEALEHAGIPPGTLRRSATGVFA 221 Query: 156 GLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALH 215 G +Y + +++D + ++G S R+SY L LRGP+VAVDTACSSSLVA+H Sbjct: 222 GACLSEYGAMASADLSQVDGWSNSGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIH 281 Query: 216 LACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEGCG 275 LACQSLR ++ +A+A GV L+LSP + ALSPTG+C+ FDA ADGFVR EG G Sbjct: 282 LACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALSPTGQCRAFDATADGFVRGEGAG 341 Query: 276 VVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADATADS 335 VVVLKRL DA RDGDRVLAV+ GSA+NQDGRSNG+ APN AAQ V+ A A Sbjct: 342 VVVLKRLTDAQRDGDRVLAVICGSAVNQDGRSNGLMAPNPAAQMAVLRAAYTNAGMQPSE 401 Query: 336 VNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIK 395 V+YVE HGTGT+LGDPIE AL G G+ + + +GSVKTNLGH EAAAGI FIK Sbjct: 402 VDYVEAHGTGTLLGDPIEARALGTVLGRGRPEDS-PLLIGSVKTNLGHTEAAAGIAGFIK 460 Query: 396 ATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNA 453 LAV HG IPPN HF NP I + R+ V +WPA RRA VSSFG GTNA Sbjct: 461 TVLAVQHGQIPPNQHFETANPHIPFTDLRMKVVDTQTEWPATGHPRRAGVSSFGFGGTNA 520 Query: 454 HVVLEQXXXXXXXDQPRSGL----SALVVSGKTPQRVAAMASALADWVDGPGGQTPLADV 509 HVV+EQ P GL S LVV+GKT QRV+A A LADW++GPG LADV Sbjct: 521 HVVIEQ--GQEVRPAPGQGLSPAVSTLVVAGKTMQRVSATAGMLADWMEGPGADVALADV 578 Query: 510 AHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQ 569 AHTLNHHR+R KF GLRALAAGQ PGV+ D PGTVFVYSG+ Sbjct: 579 AHTLNHHRSRQPKFGTVVARDRTQAIAGLRALAAGQHAPGVVNPADGSPGPGTVFVYSGR 638 Query: 570 GSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGI 629 GSQW GMGRQLLADEP+FAAA+AELEP FV QAGFSL L G E+VGI++IQ L+G+ Sbjct: 639 GSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLHDVLANGEELVGIEQIQLGLIGM 698 Query: 630 QLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXX 689 QLALT LW S+GV PD V+GHSMGEV+AAVVAGALTPA+G +V ATRSRLMA L+GQG Sbjct: 699 QLALTELWCSYGVRPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPLSGQGGM 758 Query: 690 XXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVD 749 +PQVTL ++ SP Q+V+AGP E +D +IA V QNR A R+ ++ Sbjct: 759 ALLELDAPTTEALIADFPQVTLGIYNSPRQTVIAGPTEQIDELIARVRAQNRFASRVNIE 818 Query: 750 VASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCE--QPQPVLDADYWAANLRNPVRF 807 VA H+P +D + P +RS LADLTP+ P I +I+TT QPV DA++WA N+RNPVRF Sbjct: 819 VAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPVFDAEHWATNMRNPVRF 878 Query: 808 HQAITTAGA----QHHTFVEISPHPLLTHAITDTLAAAESRTRLIT-ATLQRDGDDAITF 862 QAI +AG+ +HTF+EIS HPLLT AI DTL +A+ R + TLQRD DD +TF Sbjct: 879 QQAIASAGSGADGAYHTFIEISAHPLLTQAIIDTLHSAQPGARYTSLGTLQRDTDDVVTF 938 Query: 863 HTNL---AAVGKKPADAVTGQLADIPVTPWQHTQFWVEDR---SGISELVAAHPLLGVHI 916 TNL + IP TPWQHT+ W+ + + A LLG H Sbjct: 939 RTNLNKAHTIHPPHTPHPPEPHPPIPTTPWQHTRHWITTKYPAGSVGSAPRAGTLLGQHT 998 Query: 917 EV----PSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVDA 972 V S H+WQA + A P+ G H+ ++P +L A Sbjct: 999 TVATVSASPPSHLWQARLAPDAKPYQGGHRFHQVEVVPASVVLHTILSAAT---ELGYSA 1055 Query: 973 LSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASG-----WRRHAVAKAETS 1027 LS ++ EQ + D +L + D I + S A+G W RH A+ +S Sbjct: 1056 LS--EVRFEQPIFADR-----PRLIQVVADNRAISLASSPAAGTPSDRWTRHVTAQLSSS 1108 Query: 1028 TPSAAPGLEE------RTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSV 1081 +A L E + + D+ P DL LL G + G F+ + ++ Sbjct: 1109 PSDSASSLNEHHRANGQPPERAHRDLIP-DLAELLAMRGID-GLPFSWTVASWTQHSSNL 1166 Query: 1082 ETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSN 1141 I L + P +LDAA+ A + D Y+P S E + Sbjct: 1167 TVAIDLPEALPEGS----TGPLLDAAVHLAALSDVAD------SRLYVPASIEQI----- 1211 Query: 1142 PGRHARCRAQLTNLNDGGAGKLGRITLT----DDAG---NVTV----EINDIYLRRVERR 1190 +L D G +TL DD G +VTV E+ + +R + R Sbjct: 1212 ------------SLGDVVTGPRSSVTLNRTAHDDDGITVDVTVAAHGEVPSLSMRSLRYR 1259 Query: 1191 SVPLPLAQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFV--ARWSSPQRRVIT 1248 ++ L + A P + G +A +A FV W PQ Sbjct: 1260 ALDFGL------------DVGRAQPPASTGP----VEAYCDATNFVHTIDW-QPQTVPDA 1302 Query: 1249 ADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVW- 1307 G E GD + DG+ Q+R V+ Sbjct: 1303 THPGAEQVTHPGPVAIIGD---------DGAALCETLEGAGYQPAVMSDGVSQARYVVYV 1353 Query: 1308 ---------------------QISTVVRAIVGTWHGRAPRLWLVTEGGLVVHDEPGRPAI 1346 +I+ +VR + + LW++T G VH+ A+ Sbjct: 1354 ADSDPAGADETDVDFAVRICTEITGLVRTLAERDADKPAALWILTRG---VHESVAPSAL 1410 Query: 1347 --GALQGLVRVLAYEHPELRATLVDL---DTGADSVTRLAGELSSPRDDPNYDDVVAWRD 1401 L GL V+A EHPEL LVDL D + LA L+ P ++ RD Sbjct: 1411 RQSFLWGLAGVIAAEHPELWGGLVDLAINDDLGEFGPALAELLAKPS-----KSILVRRD 1465 Query: 1402 GHRYVTQLCRAILDPEPQRDPV-IRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGR 1460 G V A + EP R + RP A+Y++T ++A WL D GA R+VL GR Sbjct: 1466 G--VVLAPALAPVRGEPARKSLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGR 1523 Query: 1461 SE------------PSDEQRKV--LAELESRAEVV--VVCGDSATEGVAESLVAAAEDQQ 1504 + ++ +R++ + LE R V V E V L A D Sbjct: 1524 TPLPPRRDWQLDTLDTELRRRIDAIRALEMRGVTVEAVAADVGCREDVQALLAARDRDGA 1583 Query: 1505 RQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSSTAS 1564 +RGI+H A + +D L+ SMT D++ +V PK G+ LHDA +D++ +S A Sbjct: 1584 APIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFFYLTASAAG 1643 Query: 1565 LLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVA--QALVGTPLDPITP 1622 + G PGQ +YA A+++LD L RR G +++W W +G+A LV L Sbjct: 1644 IFGIPGQGSYAAANSYLDALARARRQQGCHTMSLDWVAWRGLGLAADAQLVSEEL----- 1698 Query: 1623 AEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP 1682 R G + A A+ + VV + Sbjct: 1699 ---------------ARMGSRDITPSEAFTAWEFVDGYDVAQAVVVPMPAPAGADGSGAN 1743 Query: 1683 EAL------KEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRI 1736 L M E R + + L IAA + ++ +D P ELGL+SLMA+ I Sbjct: 1744 AYLLPARNWSVMAATEVRSELEQGLRRIIAAELRVPEKE-LDTDRPFAELGLNSLMAMAI 1802 Query: 1737 RNTARADFGVEPPVTLILQGASLHDLTVDVIRQL---DLAGDEQ 1777 R A G+E T++ ++ L + +++ D++ D Q Sbjct: 1803 RREAEQFVGIELSATMLFNHPTVKSLASYLAKRVAPHDVSQDNQ 1846 >tr|A5U6T8|A5U6T8_MYCTA Tax_Id=419947 (ppsA)SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase PpsA;[Mycobacterium tuberculosis] Length = 1876 Score = 1003 bits (2592), Expect = 0.0 Identities = 701/1844 (38%), Positives = 926/1844 (50%), Gaps = 201/1844 (10%) Query: 36 EPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTK 95 EP+AVVG+GCR PG +S P++ W L + R ++ +VP RW P+ A TT+ Sbjct: 102 EPIAVVGMGCRFPGGISCPEALWDFLCERRSSISQVPPQRWQPFEGGPPEVAAALARTTR 161 Query: 96 WXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVM 155 W +P EA MDPQQR+LLEVAWEALEHAG+PP +L + T Sbjct: 162 WGSFLPDIDAFDAEFFEISPSEADKMDPQQRLLLEVAWEALEHAGIPPGTLRRSATGVFA 221 Query: 156 GLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALH 215 G +Y + +++D + ++G S R+SY L LRGP+VAVDTACSSSLVA+H Sbjct: 222 GACLSEYGAMASADLSQVDGWSNSGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIH 281 Query: 216 LACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEGCG 275 LACQSLR ++ +A+A GV L+LSP + ALSPTG+C+ FDA ADGFVR EG G Sbjct: 282 LACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALSPTGQCRAFDATADGFVRGEGAG 341 Query: 276 VVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADATADS 335 VVVLKRL DA RDGDRVLAV+ GSA+NQDGRSNG+ APN AAQ V+ A A Sbjct: 342 VVVLKRLTDAQRDGDRVLAVICGSAVNQDGRSNGLMAPNPAAQMAVLRAAYTNAGMQPSE 401 Query: 336 VNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIK 395 V+YVE HGTGT+LGDPIE AL G G+ + + +GSVKTNLGH EAAAGI FIK Sbjct: 402 VDYVEAHGTGTLLGDPIEARALGTVLGRGRPEDS-PLLIGSVKTNLGHTEAAAGIAGFIK 460 Query: 396 ATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNA 453 LAV HG IPPN HF NP I + R+ V +WPA RRA VSSFG GTNA Sbjct: 461 TVLAVQHGQIPPNQHFETANPHIPFTDLRMKVVDTQTEWPATGHPRRAGVSSFGFGGTNA 520 Query: 454 HVVLEQXXXXXXXDQPRSGL----SALVVSGKTPQRVAAMASALADWVDGPGGQTPLADV 509 HVV+EQ P GL S LVV+GKT QRV+A A LADW++GPG LADV Sbjct: 521 HVVIEQ--GQEVRPAPGQGLSPAVSTLVVAGKTMQRVSATAGMLADWMEGPGADVALADV 578 Query: 510 AHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQ 569 AHTLNHHR+R KF GLRALAAGQ PGV+ D PGTVFVYSG+ Sbjct: 579 AHTLNHHRSRQPKFGTVVARDRTQAIAGLRALAAGQHAPGVVNPADGSPGPGTVFVYSGR 638 Query: 570 GSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGI 629 GSQW GMGRQLLADEP+FAAA+AELEP FV QAGFSL L G E+VGI++IQ L+G+ Sbjct: 639 GSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLHDVLANGEELVGIEQIQLGLIGM 698 Query: 630 QLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXX 689 QLALT LW S+GV PD V+GHSMGEV+AAVVAGALTPA+G +V ATRSRLMA L+GQG Sbjct: 699 QLALTELWCSYGVRPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPLSGQGGM 758 Query: 690 XXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVD 749 +PQVTL ++ SP Q+V+AGP E +D +IA V QNR A R+ ++ Sbjct: 759 ALLELDAPTTEALIADFPQVTLGIYNSPRQTVIAGPTEQIDELIARVRAQNRFASRVNIE 818 Query: 750 VASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCE--QPQPVLDADYWAANLRNPVRF 807 VA H+P +D + P +RS LADLTP+ P I +I+TT QPV DA++WA N+RNPVRF Sbjct: 819 VAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPVFDAEHWATNMRNPVRF 878 Query: 808 HQAITTAGA----QHHTFVEISPHPLLTHAITDTLAAAESRTRLIT-ATLQRDGDDAITF 862 QAI +AG+ +HTF+EIS HPLLT AI DTL +A+ R + TLQRD DD +TF Sbjct: 879 QQAIASAGSGADGAYHTFIEISAHPLLTQAIIDTLHSAQPGARYTSLGTLQRDTDDVVTF 938 Query: 863 HTNL---AAVGKKPADAVTGQLADIPVTPWQHTQFWVEDR---SGISELVAAHPLLGVHI 916 TNL + IP TPWQHT+ W+ + + A LLG H Sbjct: 939 RTNLNKAHTIHPPHTPHPPEPHPPIPTTPWQHTRHWITTKYPAGSVGSAPRAGTLLGQHT 998 Query: 917 EV----PSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVDA 972 V S H+WQA + A P+ G H+ ++P +L A Sbjct: 999 TVATVSASPPSHLWQARLAPDAKPYQGGHRFHQVEVVPASVVLHTILSAAT---ELGYSA 1055 Query: 973 LSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASG-----WRRHAVAKAETS 1027 LS ++ EQ + D +L + D I + S A+G W RH A+ +S Sbjct: 1056 LS--EVRFEQPIFADR-----PRLIQVVADNRAISLASSPAAGTPSDRWTRHVTAQLSSS 1108 Query: 1028 TPSAAPGLEE------RTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSV 1081 +A L E + + D+ P DL LL G + G F+ + ++ Sbjct: 1109 PSDSASSLNEHHRANGQPPERAHRDLIP-DLAELLAMRGID-GLPFSWTVASWTQHSSNL 1166 Query: 1082 ETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSN 1141 I L + P +LDAA+ A + D Y+P S E + Sbjct: 1167 TVAIDLPEALPEGS----TGPLLDAAVHLAALSDVAD------SRLYVPASIEQI----- 1211 Query: 1142 PGRHARCRAQLTNLNDGGAGKLGRITLT----DDAG---NVTV----EINDIYLRRVERR 1190 +L D G +TL DD G +VTV E+ + +R + R Sbjct: 1212 ------------SLGDVVTGPRSSVTLNRTAHDDDGITVDVTVAAHGEVPSLSMRSLRYR 1259 Query: 1191 SVPLPLAQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFV--ARWSSPQRRVIT 1248 ++ L + A P + G +A +A FV W PQ Sbjct: 1260 ALDFGL------------DVGRAQPPASTGP----VEAYCDATNFVHTIDW-QPQTVPDA 1302 Query: 1249 ADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVW- 1307 G E GD + DG+ Q+R V+ Sbjct: 1303 THPGAEQVTHPGPVAIIGD---------DGAALCETLEGAGYQPAVMSDGVSQARYVVYV 1353 Query: 1308 ---------------------QISTVVRAIVGTWHGRAPRLWLVTEGGLVVHDEPGRPAI 1346 +I+ +VR + + LW++T G VH+ A+ Sbjct: 1354 ADSDPAGADETDVDFAVRICTEITGLVRTLAERDADKPAALWILTRG---VHESVAPSAL 1410 Query: 1347 --GALQGLVRVLAYEHPELRATLVDL---DTGADSVTRLAGELSSPRDDPNYDDVVAWRD 1401 L GL V+A EHPEL LVDL D + LA L+ P ++ RD Sbjct: 1411 RQSFLWGLAGVIAAEHPELWGGLVDLAINDDLGEFGPALAELLAKPS-----KSILVRRD 1465 Query: 1402 GHRYVTQLCRAILDPEPQRDPV-IRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGR 1460 G V A + EP R + RP A+Y++T ++A WL D GA R+VL GR Sbjct: 1466 G--VVLAPALAPVRGEPARKSLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGR 1523 Query: 1461 SE------------PSDEQRKV--LAELESRAEVV--VVCGDSATEGVAESLVAAAEDQQ 1504 + ++ +R++ + LE R V V E V L A D Sbjct: 1524 TPLPPRRDWQLDTLDTELRRRIDAIRALEMRGVTVEAVAADVGCREDVQALLAARDRDGA 1583 Query: 1505 RQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSSTAS 1564 +RGI+H A + +D L+ SMT D++ +V PK G+ LHDA +D++ +S A Sbjct: 1584 APIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFFYLTASAAG 1643 Query: 1565 LLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVA--QALVGTPLDPITP 1622 + G PGQ +YA A+++LD L RR G +++W W +G+A LV L Sbjct: 1644 IFGIPGQGSYAAANSYLDALARARRQQGCHTMSLDWVAWRGLGLAADAQLVSEEL----- 1698 Query: 1623 AEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP 1682 R G + A A+ + VV + Sbjct: 1699 ---------------ARMGSRDITPSEAFTAWEFVDGYDVAQAVVVPMPAPAGADGSGAN 1743 Query: 1683 EAL------KEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRI 1736 L M E R + + L IAA + ++ +D P ELGL+SLMA+ I Sbjct: 1744 AYLLPARNWSVMAATEVRSELEQGLRRIIAAELRVPEKE-LDTDRPFAELGLNSLMAMAI 1802 Query: 1737 RNTARADFGVEPPVTLILQGASLHDLTVDVIRQL---DLAGDEQ 1777 R A G+E T++ ++ L + +++ D++ D Q Sbjct: 1803 RREAEQFVGIELSATMLFNHPTVKSLASYLAKRVAPHDVSQDNQ 1846 >tr|A4TA96|A4TA96_MYCGI Tax_Id=350054 SubName: Full=Acyl transferase domain protein;[Mycobacterium gilvum] Length = 1823 Score = 994 bits (2570), Expect = 0.0 Identities = 702/1803 (38%), Positives = 927/1803 (51%), Gaps = 206/1803 (11%) Query: 36 EPVAVVGIGCRLPG---NVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYD---PDPRAP 89 + +AVVG+G R PG ++ GPD W+ L GR AV +VP RW ++YD P+ A Sbjct: 98 DAIAVVGLGVRFPGGGDDIHGPDDLWEFLAQGRSAVSQVPPTRW---SWYDDGSPEGAAA 154 Query: 90 GRMTTKWXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGT 149 TT+W +P EA MDPQQR+LLEV EALEHAG+ PD L T Sbjct: 155 LAHTTRWGSYLSEIDEFDADYFEISPSEADKMDPQQRLLLEVTHEALEHAGIRPDVLRHT 214 Query: 150 RTAAVMGLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSS 209 +T +G +Y ++ + AE++AY TG S R+SY LRGP+V +DTACSS Sbjct: 215 QTGVFVGACLGEYAVMASKDLAEVNAYSGTGGALSIIANRVSYFYDLRGPSVTIDTACSS 274 Query: 210 SLVALHLACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFV 269 SLVA+HLACQSLR +SDVALAGGV ++LSP + + + A+S +GRC FD+ ADGFV Sbjct: 275 SLVAIHLACQSLRSGDSDVALAGGVNVILSPAVTRSFDQAEAMSKSGRCHAFDSRADGFV 334 Query: 270 RSEGCGVVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLA 329 R EGCGV VLKRL DA RDGDRVLAVVRGSA+NQDGRSNG+ APN AAQ V+ +A A Sbjct: 335 RGEGCGVAVLKRLSDAQRDGDRVLAVVRGSAVNQDGRSNGLMAPNPAAQMSVLRSAYAAA 394 Query: 330 DATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCAL-GSVKTNLGHLEAAA 388 V+Y+E HGTGT+LGDPIE AL + LG+ + AD+ L G++K+NLGH EAAA Sbjct: 395 GVEPREVDYIEAHGTGTLLGDPIEARALGSV--LGRGRAADAPLLIGAIKSNLGHTEAAA 452 Query: 389 GITSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQW-PAGLRRAA-VSSF 446 GI F K LA+ G IP NL + NP I + RL V + W P G R A VSSF Sbjct: 453 GIAGFAKTVLALQRGRIPANLDYQSPNPHIPFDNLRLKVVDEVTDWKPVGRPRVAGVSSF 512 Query: 447 GLSGTNAHVVLEQXXXXXXXDQP------RSGLSALVVSGKTPQRVAAMASALADWVDGP 500 G GTNAHVVLEQ + S ++ LVV+GK+ R+A A LA+W+ G Sbjct: 513 GFGGTNAHVVLEQAPDPTPAEDTDVAPAAASPVTTLVVAGKSAPRIATTAGMLAEWLAGD 572 Query: 501 GGQTPLADVAHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQP 560 G PL VAH+LNHHRA+H KF GL+ALAAG PGV+ +P Sbjct: 573 GADVPLDQVAHSLNHHRAQHSKFATVCTRDRAGALAGLQALAAGHTAPGVVPPHQGSCRP 632 Query: 561 GTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGID 620 G VFVYSGQG+QW GMGR+LLADEP+FAAA+AELEP FV Q GFSLQQ L G V GID Sbjct: 633 GKVFVYSGQGAQWTGMGRRLLADEPAFAAAVAELEPVFVEQVGFSLQQILAGGETVTGID 692 Query: 621 RIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLM 680 RIQPVLVG+QLALT LWR++GV PDAV+GHSMGEV+A+VVAGAL+ ADG KVIATRS+LM Sbjct: 693 RIQPVLVGMQLALTELWRAYGVHPDAVIGHSMGEVAASVVAGALSVADGLKVIATRSKLM 752 Query: 681 ARLAGQGXXXXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQN 740 +RL+GQG YP VTLAV+ASP Q+V+AGPP+ VDAVIAAV+ Q+ Sbjct: 753 SRLSGQGAMALIELDPDAATALIADYPDVTLAVYASPRQTVIAGPPDQVDAVIAAVSAQD 812 Query: 741 RLARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCEQ--PQPVLDADYWA 798 RLARRIEVDVASHHP IDPILP+LR AL+ L P P IP++ TT E P+PV DADYW Sbjct: 813 RLARRIEVDVASHHPTIDPILPELREALSGLRPVSPNIPIVITTREHDGPEPVFDADYWV 872 Query: 799 ANLRNPVRFHQAITTAGAQHHTFVEISPHPLLTHAITDTLAAAESRTRLITATLQRD--- 855 NLRNPVRF QA+ AGA+ TF+E+SPHPLLT+ I+DTL + + TL R+ Sbjct: 873 DNLRNPVRFEQAVAAAGAEIGTFIEVSPHPLLTYGISDTLGTSHHHS---VPTLLRETGS 929 Query: 856 -----GDDAITFHTNL-AAVGKKPADAVTGQLAD--IPVTPWQHTQFWVE----DRSGIS 903 D+ ++FHTNL + KP + G +P TPW HT+ WV DR G S Sbjct: 930 EGDEASDETLSFHTNLNSTFTTKPPVSDHGPEPHPVLPATPWHHTRHWVAHKKVDRRGPS 989 Query: 904 ELVAAHP--LLGVHIEVP-SGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXX 960 A P LLG V S H+WQA + A P+ G H++ G ++P Sbjct: 990 ---APRPGTLLGDLTSVATSPPTHLWQARLVRDAKPYPGFHRIQGVEVVPMSVLLRTLAA 1046 Query: 961 XXXXX---------FDLPVDALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSR 1011 FD PV ++ Q++ + H T + D Sbjct: 1047 AAAESGASALADIRFDRPV------VVDQPQVIQVVAHGDTITMASAPHADAP------- 1093 Query: 1012 SASGWRRHAVAKAETSTPSAAPGLEERTSRQDETDIKPADLYALLRQAGQNHGPAFAALT 1071 A+ W RHA A+ P+ ++ + TD + + L + G G F Sbjct: 1094 -ANRWVRHATARVAQPRPADTGAVDVTAA----TDYDRSTVEELQSRWGVE-GQPFPWSI 1147 Query: 1072 RILRRPDGSVETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPV 1131 R V E+ D + A+LDAA+Q A ND + +P Sbjct: 1148 ETCRATSDGVLAEVRWQDGSA--------VALLDAAVQVARLADIND------DRLLVPA 1193 Query: 1132 SFETLRVYSNPGRHARCRAQLTNLNDGGAGKL----GRITLTDDAGNVTVEINDIYLRRV 1187 + E+L G +T G G+ +T+ DD+ V + + LR V Sbjct: 1194 AVESLTA---TGELLASSGTVTVRRRPGTGEDLVLDVAVTVPDDSTRVDI----VGLRYV 1246 Query: 1188 ERRSVPLPLAQKIFDTEWVEKSIAG----ADQPDAP-GSWLVLTDAKSNADEFVARWSSP 1242 + ++ P A D V IA A AP G+ L + + + AD Sbjct: 1247 DVQAGPAEAAPA--DPRSVAHEIAWRPWTAPSETAPAGASLAVVGSGTTADAL------- 1297 Query: 1243 QRRVITADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQS 1302 + R+ A D P+ D L + Sbjct: 1298 RERLAAAGYTDADEATAQCVLYVPGPDG--------------------------DDLDAT 1331 Query: 1303 RDTVWQISTVVRAIVGTWHGRAPRLWLVTEGGLVVHDEPGRPAI--GALQGLVRVLAYEH 1360 +++++V + PRLW++TEG V D ++ +L GL V+ E Sbjct: 1332 VRLCGEVASLVSRLADRPGTGEPRLWILTEG---VRDADSAQSLPHSSLWGLAGVVGAEQ 1388 Query: 1361 PELRATLVDLDTGAD---SVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAILDPE 1417 P+L LVD+ +GAD + LAG L +++ R G + +L A L + Sbjct: 1389 PQLWGGLVDVASGADLDETAKALAGVLPVAAKS-----ILSLRGGEFFAPEL--AALASD 1441 Query: 1418 PQRDPV-IRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGRSE------------PS 1464 P R+P+ RP A+Y++T V A WL D GA RVVL GR+ Sbjct: 1442 PVREPLRCRPDAAYLITGGLGALGLVTAEWLADRGARRVVLAGRTALPPRRRWDDDDLDK 1501 Query: 1465 DEQRKVLA--ELESRAEVVVVCG-DSATEGVAESLVAAAEDQQRQ-LRGIVHGAAVIDDS 1520 D + K+ A LE R V + D + E+L+ ++Q +RG++HGA + D Sbjct: 1502 DARDKIAAVRALELRGVAVELAPVDIGSRDAVEALLTRRDEQGAPPIRGVIHGAGLTDSQ 1561 Query: 1521 LLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSSTASLLGSPGQTAYACASAW 1580 LL + + L R PK AGA LH+ T +D+ +S ++ G PGQ AYA +A+ Sbjct: 1562 LLTDIDDERLRRTLWPKVAGARVLHELFPTDSVDFLYLTASAGTVFGVPGQGAYAAGNAY 1621 Query: 1581 LDGLVAWRRAAGLPAATINWGPWSEVG-------VAQALVGTPLDPITPAEGVVXXXXXX 1633 LDGL RR G A+++W W +G V L P+TPAE Sbjct: 1622 LDGLARARRREGGVTASLDWVAWRGLGFGSDAQVVIDELERQGSRPVTPAEAFA-----A 1676 Query: 1634 XXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXXXPEALKEMDPAEA 1693 R VA + L A + PE ++ A Sbjct: 1677 WEYASRFDVAHVVMAPTLDADEDTDQAA-----------------ESGPE--RDWSQMSA 1717 Query: 1694 RQVVTE---RLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRIRNTARADFGVEPPV 1750 VV+E L T +A + D VD+ PL E+GL+S+MA+ IR G+E Sbjct: 1718 DDVVSELESGLRTILAVELRIGD-DEVDSDRPLAEMGLNSVMAMSIRREVEKLAGIELSA 1776 Query: 1751 TLI 1753 T++ Sbjct: 1777 TML 1779 >tr|A5WRI3|A5WRI3_MYCTF Tax_Id=336982 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsA;[Mycobacterium tuberculosis] Length = 1876 Score = 994 bits (2570), Expect = 0.0 Identities = 696/1844 (37%), Positives = 924/1844 (50%), Gaps = 201/1844 (10%) Query: 36 EPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTK 95 EP+AVVG+GCR PG +S P++ W L + R ++ +VP RW P+ A TT+ Sbjct: 102 EPIAVVGMGCRFPGGISCPEALWDFLCERRSSISQVPPQRWQPFEGGPPEVAAALARTTR 161 Query: 96 WXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVM 155 W +P EA MDPQQR+LLEVAWEALEHAG+PP +L + T Sbjct: 162 WGSFLPDIDAFDAEFFEISPSEADKMDPQQRLLLEVAWEALEHAGIPPGTLRRSATGVFA 221 Query: 156 GLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALH 215 G +Y + +++D + ++G S R+SY L LRGP+VAVDTACSSSLVA+H Sbjct: 222 GACLSEYGAMASADLSQVDGWSNSGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIH 281 Query: 216 LACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEGCG 275 LACQSLR ++ +A+A GV L+LSP + ALSPTG+C+ FDA ADGFVR EG G Sbjct: 282 LACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALSPTGQCRAFDATADGFVRGEGAG 341 Query: 276 VVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADATADS 335 VVVLKRL DA RDGDRVLAV+ GSA+NQDGRSNG+ APN AAQ V+ A A Sbjct: 342 VVVLKRLTDAQRDGDRVLAVICGSAVNQDGRSNGLMAPNPAAQMAVLRAAYTNAGMQPSE 401 Query: 336 VNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIK 395 V+YVE HGTGT+LGDPIE AL G G+ + + +GSVKTNLGH EAAAGI FIK Sbjct: 402 VDYVEAHGTGTLLGDPIEARALGTVLGRGRPEDS-PLLIGSVKTNLGHTEAAAGIAGFIK 460 Query: 396 ATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNA 453 LAV HG IPPN HF NP I + R+ V +WPA RRA VSSFG GTNA Sbjct: 461 TVLAVQHGQIPPNQHFETANPHIPFTDLRMKVVDTQTEWPATGHPRRAGVSSFGFGGTNA 520 Query: 454 HVVLEQXXXXXXXDQPRSGL----SALVVSGKTPQRVAAMASALADWVDGPGGQTPLADV 509 HVV+EQ P GL S LVV+GKT QRV+A A LADW++GPG LADV Sbjct: 521 HVVIEQ--GQEVRPAPGQGLSPAVSTLVVAGKTMQRVSATAGMLADWMEGPGADVALADV 578 Query: 510 AHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQ 569 AHTLNHHR+R KF GLRALAAGQ PGV+ + PGTVFVYSG+ Sbjct: 579 AHTLNHHRSRQPKFGTVVARDRTQAIAGLRALAAGQHAPGVVNPAEGSPGPGTVFVYSGR 638 Query: 570 GSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGI 629 GSQW GMGRQLLADEP+FAAA+AELEP FV QAGFSL L G E+VGI++IQ L+G+ Sbjct: 639 GSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLHDVLANGEELVGIEQIQLGLIGM 698 Query: 630 QLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXX 689 QLALT LW S+GV PD V+GHSMGEV+AAVVAGALTPA+G +V ATRSRLMA L+GQG Sbjct: 699 QLALTELWCSYGVRPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPLSGQGGM 758 Query: 690 XXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVD 749 +PQVTL ++ SP Q+V+AGP E +D +I V ++R A R+ ++ Sbjct: 759 ALLELDAPTTEALIADFPQVTLGIYNSPRQTVIAGPTEQIDELITRVRARDRFASRVNIE 818 Query: 750 VASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCE--QPQPVLDADYWAANLRNPVRF 807 VA H+P +D + P +RS LADLTP+ P I +I+TT QPV DA++WA N+RNPV F Sbjct: 819 VAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPVFDAEHWATNMRNPVHF 878 Query: 808 HQAITTAGA----QHHTFVEISPHPLLTHAITDTLAAAESRTRLIT-ATLQRDGDDAITF 862 QAI +AG+ +HTF+EIS HPLLT AI DTL +A+ R + TLQRD DD +TF Sbjct: 879 QQAIASAGSGADGAYHTFIEISAHPLLTQAIIDTLHSAQPGARYTSLGTLQRDTDDVVTF 938 Query: 863 HTNL---AAVGKKPADAVTGQLADIPVTPWQHTQFWVEDR---SGISELVAAHPLLGVHI 916 TNL + IP TPWQHT+ W+ + + A LLG H Sbjct: 939 RTNLNKAHTIHPPHTPHPPEPHPPIPTTPWQHTRHWITTKYPAGSVGSAPRAGTLLGQHT 998 Query: 917 EV----PSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVDA 972 V S H+WQA + A P+ G H+ ++P +L A Sbjct: 999 TVATVSASPPSHLWQARLAPDAKPYQGGHRFHQVEVVPASVVLHTILSAAT---ELGYSA 1055 Query: 973 LSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASG-----WRRHAVAKAETS 1027 LS ++ EQ + D +L + D I + S A+G W RH A+ +S Sbjct: 1056 LS--EVRFEQPIFADR-----PRLIQVVADNRAISLASSPAAGTPSDRWTRHVTAQLSSS 1108 Query: 1028 TPSAAPGLEE------RTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSV 1081 +A L E + + D+ P DL LL G + G F+ + ++ Sbjct: 1109 PSDSASSLNEHHRANGQPPERAHRDLIP-DLAELLAMRGID-GLPFSWTVASWTQHSSNL 1166 Query: 1082 ETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSN 1141 I L + P +LDAA+ A + D Y+P S E + Sbjct: 1167 TVAIDLPEALPEGS----TGPLLDAAVHLAALSDVAD------SRLYVPASIEQI----- 1211 Query: 1142 PGRHARCRAQLTNLNDGGAGKLGRITLT----DDAG---NVTV----EINDIYLRRVERR 1190 +L D G +TL DD G +VTV E+ + +R + R Sbjct: 1212 ------------SLGDVVTGPRSSVTLNRTAHDDDGITVDVTVAAHGEVPSLSMRSLRYR 1259 Query: 1191 SVPLPLAQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFV--ARWSSPQRRVIT 1248 ++ L + A P + G +A +A FV W PQ Sbjct: 1260 ALDFGL------------DVGRAQPPASTGP----VEAYCDATNFVHTIDW-QPQTVPDA 1302 Query: 1249 ADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVW- 1307 G E GD + DG+ Q+R V+ Sbjct: 1303 THPGAEQVTHPGPVAIIGD---------DGAALCETLEGAGYQPAVMSDGVSQARYVVYV 1353 Query: 1308 ---------------------QISTVVRAIVGTWHGRAPRLWLVTEGGLVVHDEPGRPAI 1346 +I+ +VR + + LW++T G VH+ A+ Sbjct: 1354 ADSDPAGADETDVDFAVRICTEITGLVRTLAERDADKPAALWILTRG---VHESVAPSAL 1410 Query: 1347 --GALQGLVRVLAYEHPELRATLVDL---DTGADSVTRLAGELSSPRDDPNYDDVVAWRD 1401 L GL V+A EHPEL LVDL D + LA L+ P ++ RD Sbjct: 1411 RQSFLWGLAGVIAAEHPELWGGLVDLAINDDLGEFGPALAELLAKPS-----KSILVRRD 1465 Query: 1402 GHRYVTQLCRAILDPEPQRDPV-IRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGR 1460 G V A + EP R + RP A+Y++T ++A WL D GA R+VL GR Sbjct: 1466 G--VVLAPALAPVRGEPARKSLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGR 1523 Query: 1461 SE------------PSDEQRKV--LAELESRAEVV--VVCGDSATEGVAESLVAAAEDQQ 1504 + ++ +R++ + LE R V V E V L A D Sbjct: 1524 TPLPPRRDWQLDTLDTELRRRIDAIRALEMRGVTVEAVAADVGCREDVQALLAARDRDGA 1583 Query: 1505 RQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSSTAS 1564 +RGI+H A + +D L+ SMT D++ +V PK G+ LHDA +D++ +S A Sbjct: 1584 APIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFFYLTASAAG 1643 Query: 1565 LLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVA--QALVGTPLDPITP 1622 + G PGQ +YA A+++LD L RR G +++W W +G+A LV L Sbjct: 1644 IFGIPGQGSYAAANSYLDALARARRQQGCHTMSLDWVAWRGLGLAADAQLVSEEL----- 1698 Query: 1623 AEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP 1682 R G + A A+ + VV + Sbjct: 1699 ---------------ARMGSRDITPSEAFTAWEFVDGYDVAQAVVVPMPAPAGADGSGAN 1743 Query: 1683 EAL------KEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRI 1736 L M E R + + L IAA + ++ +D P ELGL+SLMA+ I Sbjct: 1744 AYLLPARNWSVMAATEVRSELEQGLRRIIAAELRVPEKE-LDTDRPFAELGLNSLMAMAI 1802 Query: 1737 RNTARADFGVEPPVTLILQGASLHDLTVDVIRQL---DLAGDEQ 1777 R A G+E T++ ++ L + +++ D++ D Q Sbjct: 1803 RREAEQFVGIELSATMLFNHPTVKSLASYLAKRVAPHDVSQDNQ 1846 >tr|A4KKJ1|A4KKJ1_MYCTU Tax_Id=395095 SubName: Full=Phenolpthiocerol synthesis type-I polyketide synthase ppsA;[Mycobacterium tuberculosis str. Haarlem] Length = 1876 Score = 994 bits (2570), Expect = 0.0 Identities = 696/1844 (37%), Positives = 924/1844 (50%), Gaps = 201/1844 (10%) Query: 36 EPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADRWDADAFYDPDPRAPGRMTTK 95 EP+AVVG+GCR PG +S P++ W L + R ++ +VP RW P+ A TT+ Sbjct: 102 EPIAVVGMGCRFPGGISCPEALWDFLCERRSSISQVPPQRWQPFEGGPPEVAAALARTTR 161 Query: 96 WXXXXXXXXXXXXXXXXXTPREAVAMDPQQRVLLEVAWEALEHAGLPPDSLSGTRTAAVM 155 W +P EA MDPQQR+LLEVAWEALEHAG+PP +L + T Sbjct: 162 WGSFLPDIDAFDAEFFEISPSEADKMDPQQRLLLEVAWEALEHAGIPPGTLRRSATGVFA 221 Query: 156 GLSAWDYTIVNLERRAEIDAYISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALH 215 G +Y + +++D + ++G S R+SY L LRGP+VAVDTACSSSLVA+H Sbjct: 222 GACLSEYGAMASADLSQVDGWSNSGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIH 281 Query: 216 LACQSLRLRESDVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEGCG 275 LACQSLR ++ +A+A GV L+LSP + ALSPTG+C+ FDA ADGFVR EG G Sbjct: 282 LACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALSPTGQCRAFDATADGFVRGEGAG 341 Query: 276 VVVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLADATADS 335 VVVLKRL DA RDGDRVLAV+ GSA+NQDGRSNG+ APN AAQ V+ A A Sbjct: 342 VVVLKRLTDAQRDGDRVLAVICGSAVNQDGRSNGLMAPNPAAQMAVLRAAYTNAGMQPSE 401 Query: 336 VNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTNLGHLEAAAGITSFIK 395 V+YVE HGTGT+LGDPIE AL G G+ + + +GSVKTNLGH EAAAGI FIK Sbjct: 402 VDYVEAHGTGTLLGDPIEARALGTVLGRGRPEDS-PLLIGSVKTNLGHTEAAAGIAGFIK 460 Query: 396 ATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQGAQWPA--GLRRAAVSSFGLSGTNA 453 LAV HG IPPN HF NP I + R+ V +WPA RRA VSSFG GTNA Sbjct: 461 TVLAVQHGQIPPNQHFETANPHIPFTDLRMKVVDTQTEWPATGHPRRAGVSSFGFGGTNA 520 Query: 454 HVVLEQXXXXXXXDQPRSGL----SALVVSGKTPQRVAAMASALADWVDGPGGQTPLADV 509 HVV+EQ P GL S LVV+GKT QRV+A A LADW++GPG LADV Sbjct: 521 HVVIEQ--GQEVRPAPGQGLSPAVSTLVVAGKTMQRVSATAGMLADWMEGPGADVALADV 578 Query: 510 AHTLNHHRARHGKFXXXXXXXXXXXXEGLRALAAGQPGPGVLGCQDVQNQPGTVFVYSGQ 569 AHTLNHHR+R KF GLRALAAGQ PGV+ + PGTVFVYSG+ Sbjct: 579 AHTLNHHRSRQPKFGTVVARDRTQAIAGLRALAAGQHAPGVVNPAEGSPGPGTVFVYSGR 638 Query: 570 GSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQTLTEGREVVGIDRIQPVLVGI 629 GSQW GMGRQLLADEP+FAAA+AELEP FV QAGFSL L G E+VGI++IQ L+G+ Sbjct: 639 GSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLHDVLANGEELVGIEQIQLGLIGM 698 Query: 630 QLALTALWRSHGVTPDAVVGHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGXX 689 QLALT LW S+GV PD V+GHSMGEV+AAVVAGALTPA+G +V ATRSRLMA L+GQG Sbjct: 699 QLALTELWCSYGVRPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPLSGQGGM 758 Query: 690 XXXXXXXXXXXXXXXXYPQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVD 749 +PQVTL ++ SP Q+V+AGP E +D +I V ++R A R+ ++ Sbjct: 759 ALLELDAPTTEALIADFPQVTLGIYNSPRQTVIAGPTEQIDELITRVRARDRFASRVNIE 818 Query: 750 VASHHPIIDPILPDLRSALADLTPQPPAIPMITTTCE--QPQPVLDADYWAANLRNPVRF 807 VA H+P +D + P +RS LADLTP+ P I +I+TT QPV DA++WA N+RNPV F Sbjct: 819 VAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPVFDAEHWATNMRNPVHF 878 Query: 808 HQAITTAGA----QHHTFVEISPHPLLTHAITDTLAAAESRTRLIT-ATLQRDGDDAITF 862 QAI +AG+ +HTF+EIS HPLLT AI DTL +A+ R + TLQRD DD +TF Sbjct: 879 QQAIASAGSGADGAYHTFIEISAHPLLTQAIIDTLHSAQPGARYTSLGTLQRDTDDVVTF 938 Query: 863 HTNL---AAVGKKPADAVTGQLADIPVTPWQHTQFWVEDR---SGISELVAAHPLLGVHI 916 TNL + IP TPWQHT+ W+ + + A LLG H Sbjct: 939 RTNLNKAHTIHPPHTPHPPEPHPPIPTTPWQHTRHWITTKYPAGSVGSAPRAGTLLGQHT 998 Query: 917 EV----PSGHDHVWQADVGTKACPWLGDHKVFGQAIMPXXXXXXXXXXXXXXXFDLPVDA 972 V S H+WQA + A P+ G H+ ++P +L A Sbjct: 999 TVATVSASPPSHLWQARLAPDAKPYQGGHRFHQVEVVPASVVLHTILSAAT---ELGYSA 1055 Query: 973 LSINQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSRSASG-----WRRHAVAKAETS 1027 LS ++ EQ + D +L + D I + S A+G W RH A+ +S Sbjct: 1056 LS--EVRFEQPIFADR-----PRLIQVVADNRAISLASSPAAGTPSDRWTRHVTAQLSSS 1108 Query: 1028 TPSAAPGLEE------RTSRQDETDIKPADLYALLRQAGQNHGPAFAALTRILRRPDGSV 1081 +A L E + + D+ P DL LL G + G F+ + ++ Sbjct: 1109 PSDSASSLNEHHRANGQPPERAHRDLIP-DLAELLAMRGID-GLPFSWTVASWTQHSSNL 1166 Query: 1082 ETEITLSDEAPRHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSN 1141 I L + P +LDAA+ A + D Y+P S E + Sbjct: 1167 TVAIDLPEALPEGS----TGPLLDAAVHLAALSDVAD------SRLYVPASIEQI----- 1211 Query: 1142 PGRHARCRAQLTNLNDGGAGKLGRITLT----DDAG---NVTV----EINDIYLRRVERR 1190 +L D G +TL DD G +VTV E+ + +R + R Sbjct: 1212 ------------SLGDVVTGPRSSVTLNRTAHDDDGITVDVTVAAHGEVPSLSMRSLRYR 1259 Query: 1191 SVPLPLAQKIFDTEWVEKSIAGADQPDAPGSWLVLTDAKSNADEFV--ARWSSPQRRVIT 1248 ++ L + A P + G +A +A FV W PQ Sbjct: 1260 ALDFGL------------DVGRAQPPASTGP----VEAYCDATNFVHTIDW-QPQTVPDA 1302 Query: 1249 ADLGDEXXXXXXXXXXXGDPERLPXXXXXXXXXXXXXXXXXXXXRISYDGLIQSRDTVW- 1307 G E GD + DG+ Q+R V+ Sbjct: 1303 THPGAEQVTHPGPVAIIGD---------DGAALCETLEGAGYQPAVMSDGVSQARYVVYV 1353 Query: 1308 ---------------------QISTVVRAIVGTWHGRAPRLWLVTEGGLVVHDEPGRPAI 1346 +I+ +VR + + LW++T G VH+ A+ Sbjct: 1354 ADSDPAGADETDVDFAVRICTEITGLVRTLAERDADKPAALWILTRG---VHESVAPSAL 1410 Query: 1347 --GALQGLVRVLAYEHPELRATLVDL---DTGADSVTRLAGELSSPRDDPNYDDVVAWRD 1401 L GL V+A EHPEL LVDL D + LA L+ P ++ RD Sbjct: 1411 RQSFLWGLAGVIAAEHPELWGGLVDLAINDDLGEFGPALAELLAKPS-----KSILVRRD 1465 Query: 1402 GHRYVTQLCRAILDPEPQRDPV-IRPGASYIVTXXXXXXXXVVARWLVDSGAGRVVLNGR 1460 G V A + EP R + RP A+Y++T ++A WL D GA R+VL GR Sbjct: 1466 G--VVLAPALAPVRGEPARKSLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGR 1523 Query: 1461 SE------------PSDEQRKV--LAELESRAEVV--VVCGDSATEGVAESLVAAAEDQQ 1504 + ++ +R++ + LE R V V E V L A D Sbjct: 1524 TPLPPRRDWQLDTLDTELRRRIDAIRALEMRGVTVEAVAADVGCREDVQALLAARDRDGA 1583 Query: 1505 RQLRGIVHGAAVIDDSLLFSMTKDSLERVWAPKAAGALRLHDATATRELDWWLGFSSTAS 1564 +RGI+H A + +D L+ SMT D++ +V PK G+ LHDA +D++ +S A Sbjct: 1584 APIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFFYLTASAAG 1643 Query: 1565 LLGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVGVA--QALVGTPLDPITP 1622 + G PGQ +YA A+++LD L RR G +++W W +G+A LV L Sbjct: 1644 IFGIPGQGSYAAANSYLDALARARRQQGCHTMSLDWVAWRGLGLAADAQLVSEEL----- 1698 Query: 1623 AEGVVXXXXXXXXXRGRTGVARLRSDRALIAFPEIRNLGYFTLVVQELXXXXXXXXXXXP 1682 R G + A A+ + VV + Sbjct: 1699 ---------------ARMGSRDITPSEAFTAWEFVDGYDVAQAVVVPMPAPAGADGSGAN 1743 Query: 1683 EAL------KEMDPAEARQVVTERLHTRIAAVMGYADRSAVDASMPLTELGLDSLMAVRI 1736 L M E R + + L IAA + ++ +D P ELGL+SLMA+ I Sbjct: 1744 AYLLPARNWSVMAATEVRSELEQGLRRIIAAELRVPEKE-LDTDRPFAELGLNSLMAMAI 1802 Query: 1737 RNTARADFGVEPPVTLILQGASLHDLTVDVIRQL---DLAGDEQ 1777 R A G+E T++ ++ L + +++ D++ D Q Sbjct: 1803 RREAEQFVGIELSATMLFNHPTVKSLASYLAKRVAPHDVSQDNQ 1846 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.318 0.133 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 12,650,356,533 Number of extensions: 521362704 Number of successful extensions: 1389833 Number of sequences better than 10.0: 14856 Number of HSP's gapped: 1331080 Number of HSP's successfully gapped: 23146 Length of query: 1806 Length of database: 3,846,993,858 Length adjustment: 152 Effective length of query: 1654 Effective length of database: 2,133,163,002 Effective search space: 3528251605308 Effective search space used: 3528251605308 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 88 (38.5 bits)