BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_1886 (401 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HKR4|B2HKR4_MYCMM Tax_Id=216594 (cysG)SubName: Full=Multifu... 640 0.0 tr|A0PQB6|A0PQB6_MYCUA Tax_Id=362242 (cysG)SubName: Full=Multifu... 637 0.0 tr|Q73VU5|Q73VU5_MYCPA Tax_Id=1770 (cysG2)SubName: Full=CysG2;[M... 558 e-157 tr|A0QIZ2|A0QIZ2_MYCA1 Tax_Id=243243 (cobA)SubName: Full=Uroporp... 558 e-157 tr|Q7TXQ3|Q7TXQ3_MYCBO Tax_Id=1765 (cysG)SubName: Full=POSSIBLE ... 539 e-151 tr|P95077|P95077_MYCTU Tax_Id=1773 (cysG)SubName: Full=POSSIBLE ... 539 e-151 tr|C6DWZ4|C6DWZ4_MYCTK Tax_Id=478434 SubName: Full=Multifunction... 539 e-151 tr|C1AFW1|C1AFW1_MYCBT Tax_Id=561275 (cysG)SubName: Full=Putativ... 539 e-151 tr|A5U6J9|A5U6J9_MYCTA Tax_Id=419947 (cysG)SubName: Full=Uroporp... 539 e-151 tr|A1KMJ0|A1KMJ0_MYCBP Tax_Id=410289 (cysG)SubName: Full=Possibl... 539 e-151 tr|A5WRA0|A5WRA0_MYCTF Tax_Id=336982 SubName: Full=Multi-functio... 539 e-151 tr|A2VLI0|A2VLI0_MYCTU Tax_Id=348776 SubName: Full=Multifunction... 539 e-151 tr|A4TCE9|A4TCE9_MYCGI Tax_Id=350054 SubName: Full=Uroporphyrino... 525 e-147 tr|A1T7G9|A1T7G9_MYCVP Tax_Id=350058 SubName: Full=Uroporphyrino... 518 e-145 tr|Q1BAA2|Q1BAA2_MYCSS Tax_Id=164756 SubName: Full=Uroporphyrino... 511 e-143 tr|A3PY67|A3PY67_MYCSJ Tax_Id=164757 SubName: Full=Uroporphyrino... 511 e-143 tr|A1UER0|A1UER0_MYCSK Tax_Id=189918 SubName: Full=Uroporphyrino... 511 e-143 tr|A0QVL7|A0QVL7_MYCS2 Tax_Id=246196 (cobA)SubName: Full=Uroporp... 506 e-141 tr|B1MD99|B1MD99_MYCA9 Tax_Id=561007 SubName: Full=Possible mult... 484 e-135 tr|Q0S246|Q0S246_RHOSR Tax_Id=101510 SubName: Full=Uroporphyrin-... 434 e-120 tr|Q5YSB5|Q5YSB5_NOCFA Tax_Id=37329 (cysG)SubName: Full=Putative... 433 e-119 tr|C3JM33|C3JM33_RHOER Tax_Id=596309 SubName: Full=Uroporphyrin-... 433 e-119 tr|C0ZY83|C0ZY83_RHOE4 Tax_Id=234621 (cysG)SubName: Full=Sirohem... 432 e-119 tr|C1B2Y3|C1B2Y3_RHOOB Tax_Id=632772 (cysG)SubName: Full=Sirohem... 432 e-119 tr|C2ANW8|C2ANW8_TSUPA Tax_Id=521096 SubName: Full=Uroporphyrino... 404 e-110 tr|C6WDM7|C6WDM7_ACTMD Tax_Id=446462 SubName: Full=Uroporphyrin-... 397 e-108 tr|D0LBH8|D0LBH8_GORB4 Tax_Id=526226 SubName: Full=Uroporphyrin-... 395 e-108 tr|C7MXJ3|C7MXJ3_SACVD Tax_Id=471857 SubName: Full=Uroporphyrino... 380 e-103 tr|C7QJL6|C7QJL6_CATAD Tax_Id=479433 SubName: Full=Uroporphyrin-... 374 e-101 tr|A4FM64|A4FM64_SACEN Tax_Id=405948 SubName: Full=Uroporphyrin-... 362 6e-98 tr|Q827X3|Q827X3_STRAW Tax_Id=33903 (cysG)SubName: Full=Putative... 358 5e-97 tr|C9Z603|C9Z603_STRSW Tax_Id=680198 SubName: Full=Putative urop... 356 3e-96 tr|C9NIU9|C9NIU9_9ACTO Tax_Id=591167 SubName: Full=Uroporphyrin-... 354 1e-95 tr|D1A9X0|D1A9X0_THECU Tax_Id=471852 SubName: Full=Uroporphyrin-... 352 5e-95 tr|C1WP29|C1WP29_9ACTO Tax_Id=479435 SubName: Full=Uroporphyrino... 345 4e-93 tr|Q9L1C9|Q9L1C9_STRCO Tax_Id=1902 SubName: Full=Putative uropor... 345 6e-93 tr|B1W3D1|B1W3D1_STRGG Tax_Id=455632 SubName: Full=Putative urop... 345 6e-93 tr|A1SJW9|A1SJW9_NOCSJ Tax_Id=196162 SubName: Full=Uroporphyrino... 339 3e-91 tr|C4EMJ6|C4EMJ6_STRRS Tax_Id=479432 SubName: Full=Uroporphyrino... 337 2e-90 tr|C0UBG8|C0UBG8_9ACTO Tax_Id=526225 SubName: Full=Uroporphyrino... 330 3e-88 tr|Q47MR6|Q47MR6_THEFY Tax_Id=269800 SubName: Full=Uroporphyrino... 324 1e-86 tr|C4RPH8|C4RPH8_9ACTO Tax_Id=219305 SubName: Full=Uroporphyrin-... 320 2e-85 tr|C4DDE0|C4DDE0_9ACTO Tax_Id=446470 SubName: Full=Uroporphyrino... 319 4e-85 tr|C1YQA3|C1YQA3_NOCDA Tax_Id=446468 SubName: Full=Uroporphyrino... 318 6e-85 tr|A4XAM7|A4XAM7_SALTO Tax_Id=369723 SubName: Full=Uroporphyrino... 311 9e-83 tr|A8M1Q0|A8M1Q0_SALAI Tax_Id=391037 SubName: Full=Uroporphyrin-... 311 1e-82 tr|C1RJY7|C1RJY7_9CELL Tax_Id=446466 SubName: Full=Uroporphyrino... 256 3e-66 tr|A6W7M5|A6W7M5_KINRD Tax_Id=266940 SubName: Full=Uroporphyrin-... 247 2e-63 tr|C8XJG0|C8XJG0_NAKMY Tax_Id=479431 SubName: Full=Uroporphyrin-... 243 3e-62 tr|A0LVC8|A0LVC8_ACIC1 Tax_Id=351607 SubName: Full=Uroporphyrino... 242 5e-62 >tr|B2HKR4|B2HKR4_MYCMM Tax_Id=216594 (cysG)SubName: Full=Multifunctional enzyme siroheme synthase CysG;[Mycobacterium marinum] Length = 401 Score = 640 bits (1651), Expect = 0.0 Identities = 341/401 (85%), Positives = 342/401 (85%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TESPY AQRRLPLLIASGADVQVISRSATRSVEVMDKITLT Sbjct: 1 MTESPYLVGLRLTGRKVVVVGGGTVAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG Sbjct: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLASGDH LQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV Sbjct: 121 LSVGVLASGDHRRSAAIRSAIREALQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAINDVMIERAKAG Sbjct: 181 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF Sbjct: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH Sbjct: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 Query: 361 GTTPAQHTLRATLADTPEKVRAEXXXXXXXXXXXXXXXFGV 401 GTTPAQHTLRATLADTPEKVRAE FGV Sbjct: 361 GTTPAQHTLRATLADTPEKVRAEGIRPPAIIVIGAVAAFGV 401 >tr|A0PQB6|A0PQB6_MYCUA Tax_Id=362242 (cysG)SubName: Full=Multifunctional enzyme siroheme synthase CysG;[Mycobacterium ulcerans] Length = 401 Score = 637 bits (1642), Expect = 0.0 Identities = 340/401 (84%), Positives = 341/401 (85%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TESPY AQRRLPLLIASGADVQVISRSATRSVEVMDKITLT Sbjct: 1 MTESPYLVGLRLTGRKVVVVGGGTVAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG Sbjct: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLASGDH LQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV Sbjct: 121 LSVGVLASGDHRRSAAIRSAIREALQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAINDVMIERAKAG Sbjct: 181 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF Sbjct: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPA TPVLVVQH Sbjct: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPAYTPVLVVQH 360 Query: 361 GTTPAQHTLRATLADTPEKVRAEXXXXXXXXXXXXXXXFGV 401 GTTPAQHTLRATLADTPEKVRAE FGV Sbjct: 361 GTTPAQHTLRATLADTPEKVRAEGIRPPAIIVIGAVATFGV 401 >tr|Q73VU5|Q73VU5_MYCPA Tax_Id=1770 (cysG2)SubName: Full=CysG2;[Mycobacterium paratuberculosis] Length = 401 Score = 558 bits (1439), Expect = e-157 Identities = 294/401 (73%), Positives = 315/401 (78%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TES Y AQRRLPLLIASGADV VISRSATRSVE M ITL Sbjct: 1 MTESAYLVGLRLTGKKVVVVGGGTVAQRRLPLLIASGADVHVISRSATRSVEAMTGITLQ 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 LREYRDGDL+GAWYAIAATDDP VN A+VAEA+RR+IFCVRAD+AV GTAVTPA+F++AG Sbjct: 61 LREYRDGDLDGAWYAIAATDDPRVNEAVVAEAERRRIFCVRADVAVAGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T SD ++GGVALIGGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQTGVITPEGPVGSDAVKGGVALIGGGPGDPELITV 180 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAINDVMIERA+AG Sbjct: 181 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINDVMIERARAG 240 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC +AGIPV VVPGVTSAI VPALAGVPVTHRA NHEF Sbjct: 241 SFVVRLKGGDPFVFARGYEEVLACADAGIPVTVVPGVTSAIGVPALAGVPVTHRAVNHEF 300 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+ P HPESLVNW+ALAA++GTIVLLMAVERIELF EALLKGGRPADTPVLVVQH Sbjct: 301 VVVSGHLPPGHPESLVNWDALAALTGTIVLLMAVERIELFAEALLKGGRPADTPVLVVQH 360 Query: 361 GTTPAQHTLRATLADTPEKVRAEXXXXXXXXXXXXXXXFGV 401 GTT AQHTLRATLADTPEK+RAE FGV Sbjct: 361 GTTAAQHTLRATLADTPEKIRAEGIRPPAIIVIGAVAAFGV 401 >tr|A0QIZ2|A0QIZ2_MYCA1 Tax_Id=243243 (cobA)SubName: Full=Uroporphyrin-III C-methyltransferase; EC=2.1.1.107;[Mycobacterium avium] Length = 401 Score = 558 bits (1439), Expect = e-157 Identities = 294/401 (73%), Positives = 315/401 (78%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TES Y AQRRLPLLIASGADV VISRSATRSVE M ITL Sbjct: 1 MTESAYLVGLRLTGKKVVVVGGGTVAQRRLPLLIASGADVHVISRSATRSVEAMTGITLQ 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 LREYRDGDL+GAWYAIAATDDP VN A+VAEA+RR+IFCVRAD+AV GTAVTPA+F++AG Sbjct: 61 LREYRDGDLDGAWYAIAATDDPRVNEAVVAEAERRRIFCVRADVAVAGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T SD ++GGVALIGGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQTGVITPEGPVGSDAVKGGVALIGGGPGDPELITV 180 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAINDVMIERA+AG Sbjct: 181 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINDVMIERARAG 240 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC +AGIPV VVPGVTSAI VPALAGVPVTHRA NHEF Sbjct: 241 SFVVRLKGGDPFVFARGYEEVLACADAGIPVTVVPGVTSAIGVPALAGVPVTHRAVNHEF 300 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+ P HPESLVNW+ALAA++GTIVLLMAVERIELF EALLKGGRPADTPVLVVQH Sbjct: 301 VVVSGHLPPGHPESLVNWDALAALTGTIVLLMAVERIELFAEALLKGGRPADTPVLVVQH 360 Query: 361 GTTPAQHTLRATLADTPEKVRAEXXXXXXXXXXXXXXXFGV 401 GTT AQHTLRATLADTPEK+RAE FGV Sbjct: 361 GTTAAQHTLRATLADTPEKIRAEGIRPPAIIVIGAVAAFGV 401 >tr|Q7TXQ3|Q7TXQ3_MYCBO Tax_Id=1765 (cysG)SubName: Full=POSSIBLE MULTIFUNCTIONAL ENZYME SIROHEME SYNTHASE CYSG: UROPORPHYRIN-III C-METHYLTRANSFERASE (UROGEN III METHYLASE) (SUMT) (UROPORPHYRINOGEN III METHYLASE) (UROM) + PRECORRIN-2 OXIDASE + FERROCHELATASE; EC=1.-.-.-; EC=2.1.1.107; EC=4.99.1.-;[Mycobacterium bovis] Length = 405 Score = 539 bits (1389), Expect = e-151 Identities = 282/382 (73%), Positives = 312/382 (81%), Gaps = 3/382 (0%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TE+PY AQRRLPLLIASGADV VI+ S T +VE MD+ITL+ Sbjct: 1 MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 +R+YRDGDL+GAWYAIAATDD VN A+VAEA+RR+IFCVRADIAVEGTAVTPA+F++AG Sbjct: 61 VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T+ QSSDV+ GGVAL+GGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQQGVITA---QSSDVLSGGVALVGGGPGDPELITV 177 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAIN V+IERA++G Sbjct: 178 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSG 237 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC AGIPV VVPGVTSAIAVPA+AGVPVTHRA HEF Sbjct: 238 NFVVRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEF 297 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+AP HPESLVNW+ALAA++GTIVLLMAVERIELFV+ LLKGGR ADTPVLVVQH Sbjct: 298 VVVSGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQH 357 Query: 361 GTTPAQHTLRATLADTPEKVRA 382 GTT AQ TLRATLADTPEKVRA Sbjct: 358 GTTAAQQTLRATLADTPEKVRA 379 >tr|P95077|P95077_MYCTU Tax_Id=1773 (cysG)SubName: Full=POSSIBLE MULTIFUNCTIONAL ENZYME SIROHEME SYNTHASE CYSG: UROPORPHYRIN-III C-METHYLTRANSFERASE (UROGEN III METHYLASE) (SUMT) (UROPORPHYRINOGEN III METHYLASE) (UROM) + PRECORRIN-2 OXIDASE + FERROCHELATASE; EC=1.-.-.-; EC=2.1.1.107; EC=4.99.1.-; SubName: Full=Uroporphyrinogen III methyltransferase;[Mycobacterium tuberculosis] Length = 405 Score = 539 bits (1389), Expect = e-151 Identities = 282/382 (73%), Positives = 312/382 (81%), Gaps = 3/382 (0%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TE+PY AQRRLPLLIASGADV VI+ S T +VE MD+ITL+ Sbjct: 1 MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 +R+YRDGDL+GAWYAIAATDD VN A+VAEA+RR+IFCVRADIAVEGTAVTPA+F++AG Sbjct: 61 VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T+ QSSDV+ GGVAL+GGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQQGVITA---QSSDVLSGGVALVGGGPGDPELITV 177 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAIN V+IERA++G Sbjct: 178 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSG 237 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC AGIPV VVPGVTSAIAVPA+AGVPVTHRA HEF Sbjct: 238 NFVVRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEF 297 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+AP HPESLVNW+ALAA++GTIVLLMAVERIELFV+ LLKGGR ADTPVLVVQH Sbjct: 298 VVVSGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQH 357 Query: 361 GTTPAQHTLRATLADTPEKVRA 382 GTT AQ TLRATLADTPEKVRA Sbjct: 358 GTTAAQQTLRATLADTPEKVRA 379 >tr|C6DWZ4|C6DWZ4_MYCTK Tax_Id=478434 SubName: Full=Multifunctional siroheme synthase cysG;[Mycobacterium tuberculosis] Length = 405 Score = 539 bits (1389), Expect = e-151 Identities = 282/382 (73%), Positives = 312/382 (81%), Gaps = 3/382 (0%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TE+PY AQRRLPLLIASGADV VI+ S T +VE MD+ITL+ Sbjct: 1 MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 +R+YRDGDL+GAWYAIAATDD VN A+VAEA+RR+IFCVRADIAVEGTAVTPA+F++AG Sbjct: 61 VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T+ QSSDV+ GGVAL+GGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQQGVITA---QSSDVLSGGVALVGGGPGDPELITV 177 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAIN V+IERA++G Sbjct: 178 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSG 237 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC AGIPV VVPGVTSAIAVPA+AGVPVTHRA HEF Sbjct: 238 NFVVRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEF 297 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+AP HPESLVNW+ALAA++GTIVLLMAVERIELFV+ LLKGGR ADTPVLVVQH Sbjct: 298 VVVSGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQH 357 Query: 361 GTTPAQHTLRATLADTPEKVRA 382 GTT AQ TLRATLADTPEKVRA Sbjct: 358 GTTAAQQTLRATLADTPEKVRA 379 >tr|C1AFW1|C1AFW1_MYCBT Tax_Id=561275 (cysG)SubName: Full=Putative siroheme synthase; EC=2.1.1.107;[Mycobacterium bovis] Length = 405 Score = 539 bits (1389), Expect = e-151 Identities = 282/382 (73%), Positives = 312/382 (81%), Gaps = 3/382 (0%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TE+PY AQRRLPLLIASGADV VI+ S T +VE MD+ITL+ Sbjct: 1 MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 +R+YRDGDL+GAWYAIAATDD VN A+VAEA+RR+IFCVRADIAVEGTAVTPA+F++AG Sbjct: 61 VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T+ QSSDV+ GGVAL+GGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQQGVITA---QSSDVLSGGVALVGGGPGDPELITV 177 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAIN V+IERA++G Sbjct: 178 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSG 237 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC AGIPV VVPGVTSAIAVPA+AGVPVTHRA HEF Sbjct: 238 NFVVRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEF 297 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+AP HPESLVNW+ALAA++GTIVLLMAVERIELFV+ LLKGGR ADTPVLVVQH Sbjct: 298 VVVSGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQH 357 Query: 361 GTTPAQHTLRATLADTPEKVRA 382 GTT AQ TLRATLADTPEKVRA Sbjct: 358 GTTAAQQTLRATLADTPEKVRA 379 >tr|A5U6J9|A5U6J9_MYCTA Tax_Id=419947 (cysG)SubName: Full=Uroporphyrinogen III methyltransferase;[Mycobacterium tuberculosis] Length = 405 Score = 539 bits (1389), Expect = e-151 Identities = 282/382 (73%), Positives = 312/382 (81%), Gaps = 3/382 (0%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TE+PY AQRRLPLLIASGADV VI+ S T +VE MD+ITL+ Sbjct: 1 MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 +R+YRDGDL+GAWYAIAATDD VN A+VAEA+RR+IFCVRADIAVEGTAVTPA+F++AG Sbjct: 61 VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T+ QSSDV+ GGVAL+GGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQQGVITA---QSSDVLSGGVALVGGGPGDPELITV 177 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAIN V+IERA++G Sbjct: 178 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSG 237 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC AGIPV VVPGVTSAIAVPA+AGVPVTHRA HEF Sbjct: 238 NFVVRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEF 297 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+AP HPESLVNW+ALAA++GTIVLLMAVERIELFV+ LLKGGR ADTPVLVVQH Sbjct: 298 VVVSGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQH 357 Query: 361 GTTPAQHTLRATLADTPEKVRA 382 GTT AQ TLRATLADTPEKVRA Sbjct: 358 GTTAAQQTLRATLADTPEKVRA 379 >tr|A1KMJ0|A1KMJ0_MYCBP Tax_Id=410289 (cysG)SubName: Full=Possible multifunctional enzyme siroheme synthase cysG: uroporphyrin-iii c-methyltransferase + precorrin-2 oxidase + ferrochelatase; EC=1.-.-.-; EC=2.1.1.107; EC=4.99.1.-;[Mycobacterium bovis] Length = 405 Score = 539 bits (1389), Expect = e-151 Identities = 282/382 (73%), Positives = 312/382 (81%), Gaps = 3/382 (0%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TE+PY AQRRLPLLIASGADV VI+ S T +VE MD+ITL+ Sbjct: 1 MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 +R+YRDGDL+GAWYAIAATDD VN A+VAEA+RR+IFCVRADIAVEGTAVTPA+F++AG Sbjct: 61 VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T+ QSSDV+ GGVAL+GGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQQGVITA---QSSDVLSGGVALVGGGPGDPELITV 177 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAIN V+IERA++G Sbjct: 178 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSG 237 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC AGIPV VVPGVTSAIAVPA+AGVPVTHRA HEF Sbjct: 238 NFVVRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEF 297 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+AP HPESLVNW+ALAA++GTIVLLMAVERIELFV+ LLKGGR ADTPVLVVQH Sbjct: 298 VVVSGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQH 357 Query: 361 GTTPAQHTLRATLADTPEKVRA 382 GTT AQ TLRATLADTPEKVRA Sbjct: 358 GTTAAQQTLRATLADTPEKVRA 379 >tr|A5WRA0|A5WRA0_MYCTF Tax_Id=336982 SubName: Full=Multi-functional enzyme siroheme synthase cysG: uroporphyrin-III C-methyltransferase + precorrin-2 oxidase + ferrochelatase;[Mycobacterium tuberculosis] Length = 405 Score = 539 bits (1389), Expect = e-151 Identities = 282/382 (73%), Positives = 312/382 (81%), Gaps = 3/382 (0%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TE+PY AQRRLPLLIASGADV VI+ S T +VE MD+ITL+ Sbjct: 1 MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 +R+YRDGDL+GAWYAIAATDD VN A+VAEA+RR+IFCVRADIAVEGTAVTPA+F++AG Sbjct: 61 VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T+ QSSDV+ GGVAL+GGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQQGVITA---QSSDVLSGGVALVGGGPGDPELITV 177 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAIN V+IERA++G Sbjct: 178 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSG 237 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC AGIPV VVPGVTSAIAVPA+AGVPVTHRA HEF Sbjct: 238 NFVVRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEF 297 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+AP HPESLVNW+ALAA++GTIVLLMAVERIELFV+ LLKGGR ADTPVLVVQH Sbjct: 298 VVVSGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQH 357 Query: 361 GTTPAQHTLRATLADTPEKVRA 382 GTT AQ TLRATLADTPEKVRA Sbjct: 358 GTTAAQQTLRATLADTPEKVRA 379 >tr|A2VLI0|A2VLI0_MYCTU Tax_Id=348776 SubName: Full=Multifunctional enzyme siroheme synthase cysG : uroporphyrin-III C-methyltransferase + precorrin-2 oxidase + ferrochelatase;[Mycobacterium tuberculosis C] Length = 405 Score = 539 bits (1389), Expect = e-151 Identities = 282/382 (73%), Positives = 312/382 (81%), Gaps = 3/382 (0%) Query: 1 VTESPYXXXXXXXXXXXXXXXXXXXAQRRLPLLIASGADVQVISRSATRSVEVMDKITLT 60 +TE+PY AQRRLPLLIASGADV VI+ S T +VE MD+ITL+ Sbjct: 1 MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS 60 Query: 61 LREYRDGDLEGAWYAIAATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAG 120 +R+YRDGDL+GAWYAIAATDD VN A+VAEA+RR+IFCVRADIAVEGTAVTPA+F++AG Sbjct: 61 VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG 120 Query: 121 LSVGVLASGDHXXXXXXXXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITV 180 LSVGVLA G+H LQ G++T+ QSSDV+ GGVAL+GGGPGDPELITV Sbjct: 121 LSVGVLAGGEHRRSAAIRSAIREALQQGVITA---QSSDVLSGGVALVGGGPGDPELITV 177 Query: 181 RGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAG 240 RGRRLLAQADVVVADR HVEVIDAAKIPYGRAMAQDAIN V+IERA++G Sbjct: 178 RGRRLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSG 237 Query: 241 RFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEF 300 FVVRLKGGDPFVFARGYEEVLAC AGIPV VVPGVTSAIAVPA+AGVPVTHRA HEF Sbjct: 238 NFVVRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEF 297 Query: 301 VVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQH 360 VVVSGH+AP HPESLVNW+ALAA++GTIVLLMAVERIELFV+ LLKGGR ADTPVLVVQH Sbjct: 298 VVVSGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQH 357 Query: 361 GTTPAQHTLRATLADTPEKVRA 382 GTT AQ TLRATLADTPEKVRA Sbjct: 358 GTTAAQQTLRATLADTPEKVRA 379 >tr|A4TCE9|A4TCE9_MYCGI Tax_Id=350054 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Mycobacterium gilvum] Length = 403 Score = 525 bits (1351), Expect = e-147 Identities = 266/358 (74%), Positives = 302/358 (84%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVN 85 AQRRLPLL+++GADV V++++AT +VE +D ITLTLRE+RD DL+GAWY IAATDDPAVN Sbjct: 28 AQRRLPLLVSNGADVHVVTKAATPAVEAIDGITLTLREFRDEDLDGAWYVIAATDDPAVN 87 Query: 86 AAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXL 145 AAIVA A+RR+IFCVRADIAVEGTAVTPATF + GL VGVLA G+H L Sbjct: 88 AAIVAGAERRRIFCVRADIAVEGTAVTPATFEYEGLEVGVLAGGEHRRSAAIRTAIREAL 147 Query: 146 QNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXXX 205 Q G+VT S + V++GGVAL+GGGPGDPELITVRGRRLLA ADVVVADR Sbjct: 148 QQGVVTDESGDAPGVVKGGVALVGGGPGDPELITVRGRRLLAHADVVVADRLAPQELLAE 207 Query: 206 XXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLACT 265 VEVIDA+KIPYGRAMAQDAIN V+++RAKAG+FVVRLKGGDPFVFARGYEEV+AC Sbjct: 208 LSPEVEVIDASKIPYGRAMAQDAINAVLVDRAKAGKFVVRLKGGDPFVFARGYEEVIACA 267 Query: 266 EAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAMS 325 EAGIPV VVPGVTSAIAVPALAGVPVTHR HEFVVVSGH+APDHPESLVNW+ALAAMS Sbjct: 268 EAGIPVTVVPGVTSAIAVPALAGVPVTHRGLTHEFVVVSGHLAPDHPESLVNWDALAAMS 327 Query: 326 GTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRAE 383 GTIVLLMAVERIELFV+ LLKGGRPADTPVLVVQHGTT +Q TLRA L++ PE++R++ Sbjct: 328 GTIVLLMAVERIELFVKVLLKGGRPADTPVLVVQHGTTSSQRTLRAGLSEVPERIRSD 385 >tr|A1T7G9|A1T7G9_MYCVP Tax_Id=350058 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Mycobacterium vanbaalenii] Length = 402 Score = 518 bits (1335), Expect = e-145 Identities = 263/358 (73%), Positives = 299/358 (83%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVN 85 AQRRLPLL+ASGADV VI+R+AT +VE +D ITLT+R++R GDLEGAWY IAATDDP VN Sbjct: 27 AQRRLPLLVASGADVHVITRAATPAVEAIDGITLTMRDFRAGDLEGAWYVIAATDDPEVN 86 Query: 86 AAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXL 145 AAIVAEA+ R++FCVRAD+AVEGTAVTPATF + GLSVGVLA G+H L Sbjct: 87 AAIVAEAESRRVFCVRADVAVEGTAVTPATFEYEGLSVGVLAGGEHRRSAGIRTAIREAL 146 Query: 146 QNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXXX 205 Q GL+ S + V +G VAL+GGGPGDPEL+TVRGRRLLA ADVVVADR Sbjct: 147 QRGLIGVDSSAAPGVAKGTVALVGGGPGDPELVTVRGRRLLAHADVVVADRLAPQDLLSE 206 Query: 206 XXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLACT 265 VEVIDAAKIPYGRAMAQDAIN+V+I RA+ G+FVVRLKGGDPFVFARGYEEV+AC Sbjct: 207 LSPEVEVIDAAKIPYGRAMAQDAINEVLIARAREGKFVVRLKGGDPFVFARGYEEVIACA 266 Query: 266 EAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAMS 325 EAGIPV VVPGVTSAIAVPALAGVPVTHR HEFVVVSGH+APDHPESLVNW+ALAAM+ Sbjct: 267 EAGIPVTVVPGVTSAIAVPALAGVPVTHRGLTHEFVVVSGHVAPDHPESLVNWDALAAMN 326 Query: 326 GTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRAE 383 GTIVLLMAVERIELFV+ LL+GGRPADTPVLVVQHGTT +Q TLRATL++ PE++R++ Sbjct: 327 GTIVLLMAVERIELFVKILLRGGRPADTPVLVVQHGTTSSQRTLRATLSEAPERIRSD 384 >tr|Q1BAA2|Q1BAA2_MYCSS Tax_Id=164756 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Mycobacterium sp.] Length = 398 Score = 511 bits (1316), Expect = e-143 Identities = 262/358 (73%), Positives = 295/358 (82%), Gaps = 3/358 (0%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVN 85 AQRRLPLLIA+GADV VI+R+AT +VE M ITLTLR++R GDL+GAWY IAATDDP VN Sbjct: 26 AQRRLPLLIANGADVHVIARAATPAVEAMTGITLTLRDFRVGDLDGAWYVIAATDDPDVN 85 Query: 86 AAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXL 145 AA+VAEA+RR +FCVRAD+A EGTAVTPA+F + GLSVGVLA G+H L Sbjct: 86 AAVVAEAERRHVFCVRADVAREGTAVTPASFEYEGLSVGVLAGGEHRRSAAIRSAIHEAL 145 Query: 146 QNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXXX 205 +GL++ D + GVAL+GGGPGDPELITVRGRRLLAQADVVVADR Sbjct: 146 ASGLISG---DDPDTVTTGVALVGGGPGDPELITVRGRRLLAQADVVVADRLAPQELLAE 202 Query: 206 XXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLACT 265 HVEVIDAAKIPYGRAMAQDAIN V+I+RA AG+FVVRLKGGDPFVFARGYEEVLAC Sbjct: 203 LPPHVEVIDAAKIPYGRAMAQDAINQVLIDRASAGKFVVRLKGGDPFVFARGYEEVLACV 262 Query: 266 EAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAMS 325 +AGIPV VVPGVTSAI VPALAGVPVTHR HEFVVVSGH+APDHPESLVNW+ALAA++ Sbjct: 263 DAGIPVTVVPGVTSAIGVPALAGVPVTHRHVTHEFVVVSGHVAPDHPESLVNWDALAALT 322 Query: 326 GTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRAE 383 GTIVLLMAVERIELF + L++GGRPA+TPVLVVQHGTT AQ TLRATLAD PE++ AE Sbjct: 323 GTIVLLMAVERIELFTKVLIEGGRPAETPVLVVQHGTTTAQRTLRATLADAPERMSAE 380 >tr|A3PY67|A3PY67_MYCSJ Tax_Id=164757 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Mycobacterium sp.] Length = 398 Score = 511 bits (1316), Expect = e-143 Identities = 262/358 (73%), Positives = 295/358 (82%), Gaps = 3/358 (0%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVN 85 AQRRLPLLIA+GADV VI+R+AT +VE M ITLTLR++R GDL+GAWY IAATDDP VN Sbjct: 26 AQRRLPLLIANGADVHVIARAATPAVEAMTGITLTLRDFRVGDLDGAWYVIAATDDPDVN 85 Query: 86 AAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXL 145 AA+VAEA+RR +FCVRAD+A EGTAVTPA+F + GLSVGVLA G+H L Sbjct: 86 AAVVAEAERRHVFCVRADVAREGTAVTPASFEYEGLSVGVLAGGEHRRSAAIRSAIHEAL 145 Query: 146 QNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXXX 205 +GL++ D + GVAL+GGGPGDPELITVRGRRLLAQADVVVADR Sbjct: 146 ASGLISG---DDPDTVTTGVALVGGGPGDPELITVRGRRLLAQADVVVADRLAPQELLAE 202 Query: 206 XXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLACT 265 HVEVIDAAKIPYGRAMAQDAIN V+I+RA AG+FVVRLKGGDPFVFARGYEEVLAC Sbjct: 203 LPPHVEVIDAAKIPYGRAMAQDAINQVLIDRASAGKFVVRLKGGDPFVFARGYEEVLACV 262 Query: 266 EAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAMS 325 +AGIPV VVPGVTSAI VPALAGVPVTHR HEFVVVSGH+APDHPESLVNW+ALAA++ Sbjct: 263 DAGIPVTVVPGVTSAIGVPALAGVPVTHRHVTHEFVVVSGHVAPDHPESLVNWDALAALT 322 Query: 326 GTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRAE 383 GTIVLLMAVERIELF + L++GGRPA+TPVLVVQHGTT AQ TLRATLAD PE++ AE Sbjct: 323 GTIVLLMAVERIELFTKVLIEGGRPAETPVLVVQHGTTTAQRTLRATLADAPERMSAE 380 >tr|A1UER0|A1UER0_MYCSK Tax_Id=189918 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Mycobacterium sp.] Length = 398 Score = 511 bits (1316), Expect = e-143 Identities = 262/358 (73%), Positives = 295/358 (82%), Gaps = 3/358 (0%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVN 85 AQRRLPLLIA+GADV VI+R+AT +VE M ITLTLR++R GDL+GAWY IAATDDP VN Sbjct: 26 AQRRLPLLIANGADVHVIARAATPAVEAMTGITLTLRDFRVGDLDGAWYVIAATDDPDVN 85 Query: 86 AAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXL 145 AA+VAEA+RR +FCVRAD+A EGTAVTPA+F + GLSVGVLA G+H L Sbjct: 86 AAVVAEAERRHVFCVRADVAREGTAVTPASFEYEGLSVGVLAGGEHRRSAAIRSAIHEAL 145 Query: 146 QNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXXX 205 +GL++ D + GVAL+GGGPGDPELITVRGRRLLAQADVVVADR Sbjct: 146 ASGLISG---DDPDTVTTGVALVGGGPGDPELITVRGRRLLAQADVVVADRLAPQELLAE 202 Query: 206 XXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLACT 265 HVEVIDAAKIPYGRAMAQDAIN V+I+RA AG+FVVRLKGGDPFVFARGYEEVLAC Sbjct: 203 LPPHVEVIDAAKIPYGRAMAQDAINQVLIDRASAGKFVVRLKGGDPFVFARGYEEVLACV 262 Query: 266 EAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAMS 325 +AGIPV VVPGVTSAI VPALAGVPVTHR HEFVVVSGH+APDHPESLVNW+ALAA++ Sbjct: 263 DAGIPVTVVPGVTSAIGVPALAGVPVTHRHVTHEFVVVSGHVAPDHPESLVNWDALAALT 322 Query: 326 GTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRAE 383 GTIVLLMAVERIELF + L++GGRPA+TPVLVVQHGTT AQ TLRATLAD PE++ AE Sbjct: 323 GTIVLLMAVERIELFTKVLIEGGRPAETPVLVVQHGTTTAQRTLRATLADAPERMSAE 380 >tr|A0QVL7|A0QVL7_MYCS2 Tax_Id=246196 (cobA)SubName: Full=Uroporphyrin-III C-methyltransferase; EC=2.1.1.107;[Mycobacterium smegmatis] Length = 402 Score = 506 bits (1304), Expect = e-141 Identities = 267/362 (73%), Positives = 292/362 (80%), Gaps = 7/362 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVMDK----ITLTLREYRDGDLEGAWYAIAATDD 81 AQRRLPLL+A+GADV VI+R+AT VE + K ITL LR++R GDLEGAWY IAATDD Sbjct: 26 AQRRLPLLLANGADVHVITRAATPVVEALQKDDPGITLELRDFRPGDLEGAWYVIAATDD 85 Query: 82 PAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXX 141 P VNAAI AEAD R+IFCVRADIA EG+AVTPATF H GLSVGVLA G+H Sbjct: 86 PVVNAAIAAEADERRIFCVRADIAREGSAVTPATFEHDGLSVGVLAGGEHRRSAAIRSAI 145 Query: 142 XXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXX 201 LQ GLVT + GVAL+GGGPGDPELITVRGRRLLA+ADVVVADR Sbjct: 146 HEALQQGLVTE---DMPGELTSGVALVGGGPGDPELITVRGRRLLARADVVVADRLAPQE 202 Query: 202 XXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEV 261 HVEVIDAAKIPYGRAMAQ+AIN V+IERA+AG+FVVRLKGGDPFVFARGYEEV Sbjct: 203 LLAELGPHVEVIDAAKIPYGRAMAQEAINAVLIERARAGKFVVRLKGGDPFVFARGYEEV 262 Query: 262 LACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNAL 321 LAC+EAGIPV VVPGVTSAIAVPALAGVPVTHR HEFVVVSGH+AP HPESLVNW+AL Sbjct: 263 LACSEAGIPVTVVPGVTSAIAVPALAGVPVTHRGMTHEFVVVSGHVAPGHPESLVNWDAL 322 Query: 322 AAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVR 381 AAM GTIVLLMAVERIE F + LL+GGRPADTPVLVVQHGTT AQ TL ATLAD PE++R Sbjct: 323 AAMRGTIVLLMAVERIEQFAKVLLEGGRPADTPVLVVQHGTTMAQRTLHATLADAPERIR 382 Query: 382 AE 383 +E Sbjct: 383 SE 384 >tr|B1MD99|B1MD99_MYCA9 Tax_Id=561007 SubName: Full=Possible multifunctional enzyme siroheme synthase CysG/Uroporphyrin-III C-methyltransferase-like;[Mycobacterium abscessus] Length = 398 Score = 484 bits (1246), Expect = e-135 Identities = 253/358 (70%), Positives = 282/358 (78%), Gaps = 4/358 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVN 85 AQRRL LLIASGADV VI+ AT +VE M I L LR Y+DGDL+GAWYAIA TDDPAVN Sbjct: 26 AQRRLGLLIASGADVHVIAPHATPAVEGMASINLQLRPYQDGDLDGAWYAIACTDDPAVN 85 Query: 86 AAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXL 145 AA+V EA+RR IFCVRAD A +GTAVTPA+FNH G++VGVL G H L Sbjct: 86 AAVVDEAERRHIFCVRADSARDGTAVTPASFNHDGIAVGVLTGGQHKRSAALRSAIHEAL 145 Query: 146 QNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXXX 205 Q GL+T T+ DV GVAL+GGGPGDP+LITVRGRRLLAQADVVVADR Sbjct: 146 QRGLITETA----DVKPEGVALVGGGPGDPDLITVRGRRLLAQADVVVADRLAPAELLAD 201 Query: 206 XXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLACT 265 HVEVIDAAKIPYGRAMAQ IN V+IERA+ G+FVVRLKGGDPFVFARGYEEVLAC Sbjct: 202 LGPHVEVIDAAKIPYGRAMAQQEINRVLIERAQEGKFVVRLKGGDPFVFARGYEEVLACA 261 Query: 266 EAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAMS 325 EAG+ V VVPGVTSAI+VPA AGVPVTHRA NHEFVVVSGH+AP HPESLVNW+ALAA++ Sbjct: 262 EAGVQVTVVPGVTSAISVPAAAGVPVTHRAVNHEFVVVSGHVAPGHPESLVNWDALAALN 321 Query: 326 GTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRAE 383 GTIVLLMAVERIE F L++GGRPA TPVLVVQHGTT Q LRA LA PE++R++ Sbjct: 322 GTIVLLMAVERIEQFARVLIEGGRPAHTPVLVVQHGTTDEQRVLRADLATAPERIRSQ 379 >tr|Q0S246|Q0S246_RHOSR Tax_Id=101510 SubName: Full=Uroporphyrin-III C-methyltransferase; EC=2.1.1.107;[Rhodococcus sp.] Length = 408 Score = 434 bits (1117), Expect = e-120 Identities = 229/361 (63%), Positives = 269/361 (74%), Gaps = 7/361 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRL LLIASGA V +ISR+ T +VE M +ITL LREYRDGDL AWYAIA TD+P Sbjct: 31 AQRRLGLLIASGARVHLISRAVTPAVEGMATAGQITLELREYRDGDLADAWYAIACTDEP 90 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 NAAIVAEA+R ++FCVRAD A GTAVTPA+ ++ G+S+GVLA GDH Sbjct: 91 DTNAAIVAEAERNRVFCVRADNARYGTAVTPASASYDGMSIGVLAGGDHRRSAAVRTALV 150 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 LQ+G V T+ D GVAL+GGGPGDP+LITVRGRRLLA+ADVVVADR Sbjct: 151 EGLQSGAVADTA----DHPAAGVALVGGGPGDPDLITVRGRRLLARADVVVADRLAPPEL 206 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VEVIDAAKIPYGRAMAQ+AIN +I+ AKAG+FVVRLKGGDP+VF RGYEE+ Sbjct: 207 LAELGSDVEVIDAAKIPYGRAMAQEAINAALIDGAKAGKFVVRLKGGDPYVFGRGYEELE 266 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC AG+PV VVPG+TSAI+VP+ AG+PVTHR HEFVVVSGH+APDHP+SLV+W+ALA Sbjct: 267 ACAAAGVPVTVVPGITSAISVPSAAGIPVTHRGVTHEFVVVSGHVAPDHPDSLVDWSALA 326 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 + GTIVLLMAVERIE F L++GGRP DTPV V+Q GT Q T+RA L +V+ Sbjct: 327 RLKGTIVLLMAVERIEAFATVLMEGGRPVDTPVTVIQEGTLRTQRTVRADLQTVAARVKE 386 Query: 383 E 383 E Sbjct: 387 E 387 >tr|Q5YSB5|Q5YSB5_NOCFA Tax_Id=37329 (cysG)SubName: Full=Putative uroporphyrinogen III methyltransferase;[Nocardia farcinica] Length = 423 Score = 433 bits (1113), Expect = e-119 Identities = 228/361 (63%), Positives = 266/361 (73%), Gaps = 7/361 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 A RRL LLIA+GADV VISR T +VE M +I +TLR Y DGDL AWYAIA TD+P Sbjct: 37 AARRLGLLIAAGADVHVISREVTPTVEGMASSGQIRVTLRPYADGDLAEAWYAIACTDEP 96 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 NAA+VAEA+RR++FCVRAD A GTAVTPAT + GL++GVLA G H Sbjct: 97 ETNAAVVAEAERRRVFCVRADNARLGTAVTPATARYEGLTLGVLARGAHRRSAAVRTGLL 156 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 LQ+G+V S + GVAL+GGGPGDP+LITVRGRRLLA+AD+VVADR Sbjct: 157 EALQSGVVADDSVP----VTPGVALVGGGPGDPDLITVRGRRLLARADMVVADRLAPPEL 212 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 HVEV+DAAKIPYGRAMAQ+AIN ++E A+AG+FVVRLKGGDP+VF RGYEEV Sbjct: 213 LAELGPHVEVVDAAKIPYGRAMAQEAINTALVEGARAGKFVVRLKGGDPYVFGRGYEEVQ 272 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC AG+PV VVPGVTS I+VPA AG+PVTHR HEFVVVSGH+APDHP+SLV+W+ALA Sbjct: 273 ACVAAGVPVTVVPGVTSPISVPAAAGIPVTHRGVTHEFVVVSGHVAPDHPDSLVDWSALA 332 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 + GT+VL+MAVERIE F +ALL GGRPADTP VVQ GT Q LRA L +VRA Sbjct: 333 RLRGTLVLMMAVERIEQFADALLAGGRPADTPAAVVQEGTLRTQRVLRADLGTVAARVRA 392 Query: 383 E 383 E Sbjct: 393 E 393 >tr|C3JM33|C3JM33_RHOER Tax_Id=596309 SubName: Full=Uroporphyrin-III C-methyltransferase;[Rhodococcus erythropolis SK121] Length = 408 Score = 433 bits (1113), Expect = e-119 Identities = 226/361 (62%), Positives = 272/361 (75%), Gaps = 7/361 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRL LL+ASGA V VISR+ T +VE M +IT+ R Y DGDLEGAWYAIA+TD+P Sbjct: 31 AQRRLGLLVASGARVHVISRAFTPAVEGMATAGQITVEERPYADGDLEGAWYAIASTDEP 90 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 NAAIVAEA+RR IFCVRAD A GTAVTPA+ + G+S+G+LA GDH Sbjct: 91 ETNAAIVAEAERRHIFCVRADNAKHGTAVTPASAEYDGMSIGILAGGDHRRSAAVRTAVV 150 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 LQ+G++ T+ ++ GVAL+GGGPGDP+LITVRGRRLLA+ADVVVADR Sbjct: 151 EGLQSGVLADTAEPAA----AGVALVGGGPGDPDLITVRGRRLLARADVVVADRLAPPEL 206 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VEVIDAAKIPYGRAMAQ+AIN +I+ AKAG+FVVRLKGGDP+VF RGYEE+ Sbjct: 207 LAELGPDVEVIDAAKIPYGRAMAQEAINAALIDNAKAGKFVVRLKGGDPYVFGRGYEELE 266 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC AG+PV VVPG+TSAI+VP+ AG+PVTHR HEFVVVSGH+APDHP+SLV+W+ALA Sbjct: 267 ACAAAGVPVTVVPGITSAISVPSAAGIPVTHRGVTHEFVVVSGHVAPDHPDSLVDWSALA 326 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 + GTIVLLMAVERI+ F ++L+ GGRPA TPV V+Q GT Q LRA LA ++V+ Sbjct: 327 KLRGTIVLLMAVERIDQFAKSLVDGGRPATTPVTVIQEGTLRTQRELRADLATVAQRVKD 386 Query: 383 E 383 E Sbjct: 387 E 387 >tr|C0ZY83|C0ZY83_RHOE4 Tax_Id=234621 (cysG)SubName: Full=Siroheme synthase CysG; EC=1.3.1.76; EC=2.1.1.107; EC=4.99.1.4;[Rhodococcus erythropolis] Length = 408 Score = 432 bits (1112), Expect = e-119 Identities = 226/361 (62%), Positives = 271/361 (75%), Gaps = 7/361 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRL LL+ASGA V VISR+ T +VE M +IT+ R Y DGDLEGAWYAIA+TD+P Sbjct: 31 AQRRLGLLVASGARVHVISRAFTPAVEGMATAGQITVEERPYADGDLEGAWYAIASTDEP 90 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 NAAIVAEA+RR IFCVRAD A GTAVTPA+ + G+S+G+LA GDH Sbjct: 91 ETNAAIVAEAERRHIFCVRADNAKHGTAVTPASAEYDGMSIGILAGGDHRRSAAVRTAVV 150 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 LQ+G++ T+ ++ GVAL+GGGPGDP+LITVRGRRLLA+ADVVVADR Sbjct: 151 EGLQSGVLADTAEPAA----AGVALVGGGPGDPDLITVRGRRLLARADVVVADRLAPPEL 206 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VEVIDAAKIPYGRAMAQ+AIN +I+ AKAG+FVVRLKGGDP+VF RGYEE+ Sbjct: 207 LAELGPDVEVIDAAKIPYGRAMAQEAINAALIDNAKAGKFVVRLKGGDPYVFGRGYEELE 266 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC AG+PV VVPG+TSAI+VP+ AG+PVTHR HEFVVVSGH+APDHP+SLV+W+ALA Sbjct: 267 ACAAAGVPVTVVPGITSAISVPSAAGIPVTHRGVTHEFVVVSGHVAPDHPDSLVDWSALA 326 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 + GTIVLLMAVERI+ F AL+ GGRP+ TPV V+Q GT Q LRA LA ++V+ Sbjct: 327 KLRGTIVLLMAVERIDQFARALVDGGRPSTTPVTVIQEGTLRTQRELRADLATVAQRVKD 386 Query: 383 E 383 E Sbjct: 387 E 387 >tr|C1B2Y3|C1B2Y3_RHOOB Tax_Id=632772 (cysG)SubName: Full=Siroheme synthase CysG; EC=1.3.1.76; EC=2.1.1.107; EC=4.99.1.4;[Rhodococcus opacus] Length = 408 Score = 432 bits (1111), Expect = e-119 Identities = 227/361 (62%), Positives = 267/361 (73%), Gaps = 7/361 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRL LLIASGA V +ISR T +VE M +IT+ LREYRDGDL AWYAIA TD+P Sbjct: 31 AQRRLGLLIASGARVHLISREVTPAVEGMATAGQITVDLREYRDGDLADAWYAIACTDEP 90 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 NAAIVAEA+R ++FCVRAD A GTAVTPA+ ++ G+S+GVLA GDH Sbjct: 91 DTNAAIVAEAERNRVFCVRADNARYGTAVTPASASYDGMSIGVLAGGDHRRSAAVRTALV 150 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 LQ+G V T+ + GVAL+GGGPGDP+LITVRGRRLLA+ADVVVADR Sbjct: 151 EGLQSGAVADTAEPPA----AGVALVGGGPGDPDLITVRGRRLLARADVVVADRLAPPEL 206 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VEVIDAAKIPYGRAMAQ+AIN +++ AKAG+FVVRLKGGDP+VF RGYEE+ Sbjct: 207 LAELGSDVEVIDAAKIPYGRAMAQEAINAALVDGAKAGKFVVRLKGGDPYVFGRGYEELE 266 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC AG+PV VVPG+TSAI+VP+ AG+PVTHR HEFVVVSGH+APDHP+SLV+W+ALA Sbjct: 267 ACAAAGVPVTVVPGITSAISVPSAAGIPVTHRGVTHEFVVVSGHVAPDHPDSLVDWSALA 326 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 + GTIVLLMAVERIE F L+ GGRP DTPV V+Q GT Q TLRA L +V+ Sbjct: 327 RLKGTIVLLMAVERIEAFATVLMDGGRPVDTPVTVIQEGTLRTQRTLRADLQTVAARVKE 386 Query: 383 E 383 E Sbjct: 387 E 387 >tr|C2ANW8|C2ANW8_TSUPA Tax_Id=521096 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Tsukamurella paurometabola DSM 20162] Length = 411 Score = 404 bits (1037), Expect = e-110 Identities = 211/347 (60%), Positives = 249/347 (71%), Gaps = 5/347 (1%) Query: 27 QRRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVNA 86 QRRLP L+A+GADV VI+ AT +VE IT REY DGDL GAWYA+AATDDPAVNA Sbjct: 32 QRRLPPLLAAGADVHVIAPEATPAVESTVGITWHRREYADGDLAGAWYALAATDDPAVNA 91 Query: 87 AIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXLQ 146 +VAEA ++ FCVRAD+A EGTAVTPAT GL VGVLA+GDH L Sbjct: 92 RVVAEAQAQRTFCVRADLAREGTAVTPATVATDGLQVGVLAAGDHRRSAAVRNALGAVLT 151 Query: 147 NGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXXXX 206 + + GVAL+GGGPGDP+LITVRGR LLA ADVVVADR Sbjct: 152 GDEAARPTRKPE-----GVALVGGGPGDPDLITVRGRALLAVADVVVADRLAPPRLLAEL 206 Query: 207 XXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLACTE 266 HVEVIDAAK+PYGRAMAQ AIN V+I+RA+ G+FVVRLKGGDP+VF RGYEE+ A Sbjct: 207 APHVEVIDAAKVPYGRAMAQQAINQVLIDRAREGKFVVRLKGGDPYVFGRGYEELEALAA 266 Query: 267 AGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAMSG 326 GIPV VVPG+TS+IA P+ AG+PVTHR HEFVVVSGH+AP HP+SLV+W+AL + G Sbjct: 267 EGIPVTVVPGITSSIAAPSAAGIPVTHRGVTHEFVVVSGHVAPGHPDSLVDWDALGRLRG 326 Query: 327 TIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATL 373 T+V+LMAVER+ + EAL+ GGRP+DTP VV+ TT Q T+R TL Sbjct: 327 TVVVLMAVERLGVIAEALIAGGRPSDTPAAVVESATTGGQRTVRGTL 373 >tr|C6WDM7|C6WDM7_ACTMD Tax_Id=446462 SubName: Full=Uroporphyrin-III C-methyltransferase;[Actinosynnema mirum] Length = 405 Score = 397 bits (1021), Expect = e-108 Identities = 210/360 (58%), Positives = 256/360 (71%), Gaps = 9/360 (2%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVE-VMDK--ITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRLP L++SGA V+++S T +V+ V+D +T R Y DGDL+GAWY +A T DP Sbjct: 27 AQRRLPRLVSSGARVELVSPEVTPTVQGVVDSGAVTWHARRYADGDLDGAWYVLACTSDP 86 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 VNA I A+A+ R++FCVRAD+ GTAVTPA+ NH GL VGVLASGDH Sbjct: 87 EVNARITADAEARRVFCVRADVGALGTAVTPASGNHDGLLVGVLASGDHNRSARVRDGVL 146 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 L++G + Q + GVAL+GGGPGDP+LITVRGRRLLA+ADVVVADR Sbjct: 147 SALRDGTLADQHDQPA-----GVALVGGGPGDPDLITVRGRRLLARADVVVADRLGPVWL 201 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 HVEV+DAAKIPYGRA AQ+ IN +++ AKAG+FVVRLKGGDP+VF RG+EE++ Sbjct: 202 LDELPPHVEVVDAAKIPYGRAAAQEFINRTLVDNAKAGKFVVRLKGGDPYVFGRGFEELI 261 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC EAG+PV VVPGVTSA VPALAGVPVTHR HE VVVSGH+APD SLV+W ALA Sbjct: 262 ACAEAGVPVTVVPGVTSAFGVPALAGVPVTHRGVAHEVVVVSGHVAPDDERSLVDWGALA 321 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 + GT+V+LM VER F A L+ GRP DTPV VV++G+T AQ +R+TL E V A Sbjct: 322 RLRGTVVILMGVERAAAFA-AALREGRPGDTPVTVVENGSTDAQRIVRSTLDGLAEAVAA 380 >tr|D0LBH8|D0LBH8_GORB4 Tax_Id=526226 SubName: Full=Uroporphyrin-III C-methyltransferase;[Gordonia bronchialis] Length = 413 Score = 395 bits (1014), Expect = e-108 Identities = 202/359 (56%), Positives = 252/359 (70%), Gaps = 5/359 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVN 85 AQRRLP L++SGA V VI+ T +VE + + R Y DGDL+GAWYA+A TDDPAVN Sbjct: 38 AQRRLPNLVSSGAQVHVIAIDPTPAVESFAGVHVHQRAYADGDLDGAWYAMACTDDPAVN 97 Query: 86 AAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXL 145 AA+VAEA+RR FCVRAD A GTAVTPA+ H + GVLA GDH L Sbjct: 98 AAVVAEAERRHTFCVRADDARFGTAVTPASGRHRDVRFGVLAGGDHRLSAALRAAISRAL 157 Query: 146 QNGLVTSTSYQSSDVIR-GGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXX 204 +G +T D R GVAL+GGGPGDP+LITVRG+RLLA ADVVVADR Sbjct: 158 ADGSLTV----EDDTRRPAGVALVGGGPGDPDLITVRGQRLLADADVVVADRLAPPELLA 213 Query: 205 XXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLAC 264 VE+IDAAK+PYGRAM Q+AINDV++ +A+ G+FVVRLKGGDP+V+ RG+EE+ AC Sbjct: 214 ALGPQVEIIDAAKVPYGRAMKQEAINDVLVAKAREGKFVVRLKGGDPYVYGRGFEELQAC 273 Query: 265 TEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAM 324 AG+PV VVPG++S+IA PA AG+PVTHR HE V+ SGH+ P HP+SL++W ALA + Sbjct: 274 VAAGVPVTVVPGISSSIAAPASAGIPVTHRGVTHEVVIASGHVPPGHPDSLIDWAALAKL 333 Query: 325 SGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRAE 383 GT+VL+MAVER+E+F +ALL GGRP TPV ++++G+ P Q LR LA E E Sbjct: 334 RGTLVLMMAVERVEVFADALLDGGRPPATPVAMIENGSLPTQRVLRTDLAHAGEVAAQE 392 >tr|C7MXJ3|C7MXJ3_SACVD Tax_Id=471857 SubName: Full=Uroporphyrinogen-III C-methyltransferase;[Saccharomonospora viridis] Length = 414 Score = 380 bits (975), Expect = e-103 Identities = 206/359 (57%), Positives = 246/359 (68%), Gaps = 5/359 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRLP L+A+GA V++++ T SV+ + ++ R YR GDL+GAWYA+A +DD Sbjct: 29 AQRRLPRLLAAGAAVELVAPHTTPSVQALAESKELVWHPRPYRAGDLDGAWYALACSDDA 88 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 VNAA+ AEA+R +IFCVRAD GTAVTPAT H GL VGVL SG Sbjct: 89 NVNAAVAAEAERARIFCVRADAGEHGTAVTPATGYHDGLLVGVL-SGAPRRSAAVRDAVL 147 Query: 143 XXLQNGLVTSTSYQSSDVIRG-GVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXX 201 +++GL+ Q D G GVAL+GGGPGDPELITVRGRRLL++ADVVV DR Sbjct: 148 DGVRSGLILDGDEQWGDESPGPGVALVGGGPGDPELITVRGRRLLSRADVVVVDRLAPRE 207 Query: 202 XXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEV 261 VEVIDAAKIPYGRA+AQ AIN +IE A+AGRFVVRLKGGDP+VF RG+EEV Sbjct: 208 LLDELPDQVEVIDAAKIPYGRAVAQKAINQALIEHARAGRFVVRLKGGDPYVFGRGFEEV 267 Query: 262 LACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNAL 321 LAC EAG+PV VVPGVTSA +VPA AGVPVTHR HE VVVSGH+ P SLV+W AL Sbjct: 268 LACAEAGVPVTVVPGVTSAFSVPAAAGVPVTHRGVAHEVVVVSGHVPPGDERSLVDWEAL 327 Query: 322 AAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKV 380 + GT+VLLM VE I LFV+AL+ GRP TP V+Q GT Q +RA L+ + V Sbjct: 328 GRLRGTVVLLMGVEHIGLFVDALIAAGRPGSTPAAVIQEGTLRTQRVVRAPLSGLADAV 386 >tr|C7QJL6|C7QJL6_CATAD Tax_Id=479433 SubName: Full=Uroporphyrin-III C-methyltransferase;[Catenulispora acidiphila] Length = 405 Score = 374 bits (960), Expect = e-101 Identities = 193/358 (53%), Positives = 249/358 (69%), Gaps = 6/358 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRR+ L+ + ADV V++ AT ++E + +I R YRDGDL AWYA+AA DDP Sbjct: 31 AQRRVLGLLDARADVLVVAPEATPAIEALADGGEIVWEPRPYRDGDLAQAWYAVAAADDP 90 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 AVN A+ EA+ ++FC RAD A + TA TPA H G++V V+ GD Sbjct: 91 AVNGAVAREAEAGRVFCSRADSAEDSTAWTPAVGRHDGVTVAVIGGGDPRRAVDVRDGVL 150 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 L++G + + ++ GVAL+GGGPGDP+LITVRGRRLLA+ADVVVADR Sbjct: 151 EGLRDGTLAAPHHRGRTP---GVALVGGGPGDPDLITVRGRRLLAEADVVVADRLGPRGL 207 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VE++DA+KIPYGR++AQ+AIN+++IERAKAG+FVVRLKGGDPFVF RG+EEVL Sbjct: 208 LDELAPDVEIVDASKIPYGRSLAQEAINELLIERAKAGKFVVRLKGGDPFVFGRGFEEVL 267 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC EAG+P VVPG+TS+I+VPALAG+PVTHR HEF VVSGH+APD+P+SLV+W AL Sbjct: 268 ACAEAGVPCSVVPGITSSISVPALAGIPVTHRGVAHEFTVVSGHVAPDNPKSLVDWAALG 327 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKV 380 M+GT+V+LM +ERI E LL GR +TPV V+Q GT P + ++ TL E V Sbjct: 328 RMTGTLVILMGIERIAAIAETLLAHGRGPETPVAVIQEGTMPGERRVQTTLGMIGEAV 385 >tr|A4FM64|A4FM64_SACEN Tax_Id=405948 SubName: Full=Uroporphyrin-III C-methyltransferase; EC=2.1.1.107;[Saccharopolyspora erythraea] Length = 407 Score = 362 bits (928), Expect = 6e-98 Identities = 192/361 (53%), Positives = 242/361 (67%), Gaps = 7/361 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRR+P LI +GA V+VI+ AT +VE M ++ R Y +GDL+GAWYA+A Sbjct: 29 AQRRVPRLINAGALVEVIAPEATPAVEAMADAGELRWHRRPYAEGDLDGAWYALACATGG 88 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 VNAA+ EA RR++FCVRAD A GTAVTPA H GL +GVLA GDH Sbjct: 89 EVNAAVADEALRRRVFCVRADDASRGTAVTPAVAEHGGLLLGVLAGGDHRRSAAVRDALA 148 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 L+ G+V +S++ GVAL+GGGPGDP+LITVRGR+LL +ADVV+ DR Sbjct: 149 EALRTGVVD----ESAEAPAPGVALVGGGPGDPDLITVRGRQLLGRADVVITDRLAPREL 204 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 HVEV+DA+KIPYGRA QD IN ++IE A+AG+FVVRLKGGDP+VF RG+EE+L Sbjct: 205 LEELGPHVEVVDASKIPYGRAANQDVINSLLIEHARAGKFVVRLKGGDPYVFGRGFEELL 264 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC EAG+ V VPG+TSA + P+ A VPVTHR HE VVVSGH+ P +SLV+W ALA Sbjct: 265 ACVEAGVAVTAVPGITSAFSAPSAADVPVTHRGVAHEVVVVSGHVGPHDEQSLVDWPALA 324 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 + GT+VL+MAV+RI F L++ GR +PV VVQ TT Q LR+TL + +R Sbjct: 325 KLRGTLVLMMAVKRIGEFAAVLIEHGRDPKSPVAVVQEATTRGQRALRSTLDGVADAIRD 384 Query: 383 E 383 E Sbjct: 385 E 385 >tr|Q827X3|Q827X3_STRAW Tax_Id=33903 (cysG)SubName: Full=Putative uroporphyrin-III methyltransferase;[Streptomyces avermitilis] Length = 410 Score = 358 bits (920), Expect = 5e-97 Identities = 196/362 (54%), Positives = 240/362 (66%), Gaps = 4/362 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRLP LIA+GA V ++S AT SVE M +IT + R Y DGDL AWYA+ AT D Sbjct: 27 AQRRLPALIAAGAKVHLVSPEATPSVEAMADTGEITWSRRRYEDGDLAEAWYALIATSDA 86 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 A N A AEA+R +++CVR+D A TA TPAT + G++V VL + Sbjct: 87 AANVAASAEAERLRVWCVRSDDADAATAWTPATGHSEGVTVAVLTTNAKGRDPRHTAAIR 146 Query: 143 XXLQNGLVTSTSYQSSDVIRG-GVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXX 201 + GL T +R GVAL+GGGPGDP+LITVRGRRLLA+ADVV+ADR Sbjct: 147 DAVVEGLRDGTLVAPHHRVRTPGVALVGGGPGDPDLITVRGRRLLAEADVVIADRLGPRD 206 Query: 202 XXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEV 261 HVEVIDAAKIPYGR MAQ+AIN+ +IE A+ G+ VVRLKGGDPFVF RG EE Sbjct: 207 LLAELPPHVEVIDAAKIPYGRFMAQEAINNALIEHARQGKSVVRLKGGDPFVFGRGMEEA 266 Query: 262 LACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNAL 321 A E GIP VVPG++S+I+VP AG+PVTHR HEF VVSGH+APD SLV+W AL Sbjct: 267 QALAEVGIPCTVVPGISSSISVPGAAGIPVTHRGVAHEFTVVSGHVAPDDERSLVDWPAL 326 Query: 322 AAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVR 381 A + GT+V+LM V++I + L+ G+PA TPV +VQ GTT AQ + ATLA E VR Sbjct: 327 AKLRGTLVILMGVDKIGKIADTLVAHGKPAGTPVALVQEGTTAAQRRVDATLATVAETVR 386 Query: 382 AE 383 A+ Sbjct: 387 AQ 388 >tr|C9Z603|C9Z603_STRSW Tax_Id=680198 SubName: Full=Putative uroporphyrin-III methyltransferase;[Streptomyces scabies] Length = 393 Score = 356 bits (913), Expect = 3e-96 Identities = 194/362 (53%), Positives = 240/362 (66%), Gaps = 4/362 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRLP LIA+GA + ++S SAT SVE M ++T R Y +GDL AWY + AT DP Sbjct: 10 AQRRLPALIAAGAHIVLVSPSATPSVEAMADAGELTWERRRYAEGDLAEAWYVLVATGDP 69 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 NA AEA+R +I+CVRAD A E TA TPAT + G++V VL + Sbjct: 70 VANARASAEAERHRIWCVRADSAEEATAWTPATGHSEGVTVAVLTANAQERDPRHTAAIR 129 Query: 143 XXLQNGLVTSTSYQSSDVIRG-GVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXX 201 + GL T R GV+L+GGGPGDP+LITVRGRRLLA+ADVV+ADR Sbjct: 130 DAVVEGLRDGTLVAPHHRTRTPGVSLVGGGPGDPDLITVRGRRLLAEADVVIADRLGPRD 189 Query: 202 XXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEV 261 HVEVIDAAKIPYGR MAQ+AIN+ +IE AK G+ VVRLKGGDP+VF RG EE+ Sbjct: 190 LLAELPPHVEVIDAAKIPYGRFMAQEAINNALIEHAKQGKSVVRLKGGDPYVFGRGMEEL 249 Query: 262 LACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNAL 321 A EAGIP VVPG++S+I+VP+ AG+PVTHR HEF VVSGH+APD SLV+W AL Sbjct: 250 HALAEAGIPCTVVPGISSSISVPSAAGIPVTHRGVAHEFTVVSGHVAPDDERSLVDWPAL 309 Query: 322 AAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVR 381 A ++GT+V+LM V++I E L+ G+ DTPV +VQ GTT AQ + ATLA VR Sbjct: 310 ARLTGTLVILMGVDKIGRIAETLVAHGKSPDTPVALVQEGTTAAQRRVDATLATVAATVR 369 Query: 382 AE 383 + Sbjct: 370 TQ 371 >tr|C9NIU9|C9NIU9_9ACTO Tax_Id=591167 SubName: Full=Uroporphyrin-III C-methyltransferase;[Streptomyces flavogriseus ATCC 33331] Length = 424 Score = 354 bits (908), Expect = 1e-95 Identities = 194/362 (53%), Positives = 237/362 (65%), Gaps = 4/362 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRLP LIA+GAD+ ++S SAT SVE M +I R Y+DGDL WYA+ A+ D Sbjct: 30 AQRRLPALIATGADITLVSPSATASVEAMADAGEIRWERRRYQDGDLTDTWYALVASSDA 89 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 A N A AEA+R + +CVR+D A TA TPAT G+++ VL + Sbjct: 90 AANDAASAEAERTRTWCVRSDDAEAATAWTPATGRSEGITIAVLTTTSQGRDPRHSAAVR 149 Query: 143 XXLQNGLVTSTSYQSSDVIRG-GVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXX 201 + GL T R GVAL+GGGPGDP+LITVRGRRLLA+ADVV+ADR Sbjct: 150 DAIVEGLRDGTLAAPHHRTRAPGVALVGGGPGDPDLITVRGRRLLAEADVVIADRLGPRD 209 Query: 202 XXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEV 261 HVEVIDAAKIPYGR MAQ+AIN +I+ AKAG+ VVRLKGGDPFVF RG EE Sbjct: 210 LLDELPPHVEVIDAAKIPYGRYMAQEAINQALIDHAKAGKSVVRLKGGDPFVFGRGMEEA 269 Query: 262 LACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNAL 321 A GI VVPG++S+I+VP AG+PVTHR HEF VVSGH+AP+ P SLV+W AL Sbjct: 270 QALAAEGIACTVVPGISSSISVPGAAGIPVTHRGVAHEFTVVSGHVAPEDPRSLVDWKAL 329 Query: 322 AAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVR 381 A + GT+VLLMAV++I AL+ G+ +TPV +VQ GTT AQ + ATLAD E+V Sbjct: 330 AQLRGTLVLLMAVDKIGAISRALIAHGKSPETPVALVQEGTTAAQRRVDATLADVGERVV 389 Query: 382 AE 383 AE Sbjct: 390 AE 391 >tr|D1A9X0|D1A9X0_THECU Tax_Id=471852 SubName: Full=Uroporphyrin-III C-methyltransferase;[Thermomonospora curvata DSM 43183] Length = 448 Score = 352 bits (903), Expect = 5e-95 Identities = 192/360 (53%), Positives = 236/360 (65%), Gaps = 6/360 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRR+P L+A+GA+V +++ T S++ + ++T R YR GDLEGAW A +DDP Sbjct: 42 AQRRVPALLAAGAEVVLVAPEVTPSLDGLIADGRLTWLRRPYRTGDLEGAWLVQAVSDDP 101 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 VNAA+ AEA+R +I+CVRAD A A TPA+ +VGVLA GD Sbjct: 102 KVNAAVAAEAERARIWCVRADDAQASAAWTPASGQVGETTVGVLAGGDPRRAAGIRDAIV 161 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 L++ + + + V GVAL+GGGPGDP LITVRGR+LLAQADVV+ DR Sbjct: 162 DGLRDATLEARHSRRKPV---GVALVGGGPGDPGLITVRGRQLLAQADVVITDRLAPRLL 218 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VEVIDAAKIPYGR + Q+ IND ++E A+AG+FVVRLKGGDPFVF RG EEVL Sbjct: 219 LDELPSDVEVIDAAKIPYGRTVTQEKINDYLVEHARAGKFVVRLKGGDPFVFGRGAEEVL 278 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 C GIPV VVPGVTSA+AVPA AG+PVTHR + EF VVS H+ P HP S V+W AL Sbjct: 279 HCARHGIPVTVVPGVTSAVAVPAAAGIPVTHRGVSQEFHVVSAHVDPAHPASTVDWEALG 338 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 GT+VLLMAVER+ AL++ GR DTPV VVQ GT P Q L ATL E++ A Sbjct: 339 RSQGTLVLLMAVERMGRIANALMRYGRSPDTPVAVVQDGTLPDQRALTATLGTVVEEMAA 398 >tr|C1WP29|C1WP29_9ACTO Tax_Id=479435 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Kribbella flavida DSM 17836] Length = 414 Score = 345 bits (886), Expect = 4e-93 Identities = 183/360 (50%), Positives = 237/360 (65%), Gaps = 9/360 (2%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRLP L+ +GA + VIS + T ++E + + R Y GDLEGAWY + ATDD Sbjct: 27 AQRRLPRLLETGAQIDVISPAITPTIEGLLTNPDLRWVERGYAPGDLEGAWYVVVATDDD 86 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 AVN + AEA++R+IFCVR+D TA TPA+ H ++VGVL +GDH Sbjct: 87 AVNDQVSAEAEQRRIFCVRSDDRSRATAWTPASGQHDHVTVGVLGAGDHRRSAAVRDAIL 146 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 L+ G + + + GV L+GGGPGDP+LITVRGRRLLA+ADVVVADR Sbjct: 147 EELRTGALGARDSLDK---KPGVYLVGGGPGDPDLITVRGRRLLAEADVVVADRLAPQQL 203 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VE+IDAAK+P GR+ Q+ IN +++ERA+ G+ VVRLKGGDP+VF RG+EE + Sbjct: 204 LDELHSDVELIDAAKLPRGRSAQQEEINRILVERAQQGKLVVRLKGGDPYVFGRGFEEAI 263 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC EAG+ VVPG+TS+I+VPA++G+PVTHR HEF VVSGHI PDHP+SLVNW ALA Sbjct: 264 ACAEAGVQWTVVPGITSSISVPAVSGIPVTHRGVTHEFTVVSGHIPPDHPDSLVNWPALA 323 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRA---TLADTPEK 379 ++GT+VLLMAVE + L GR + TP V+ GT P Q + A T+A T E+ Sbjct: 324 QLNGTLVLLMAVENLPKIAATLTAHGRASTTPAAVIADGTLPGQRMVTADLGTIAATVEQ 383 >tr|Q9L1C9|Q9L1C9_STRCO Tax_Id=1902 SubName: Full=Putative uroporphyrin-III methyltransferase;[Streptomyces coelicolor] Length = 410 Score = 345 bits (885), Expect = 6e-93 Identities = 190/362 (52%), Positives = 235/362 (64%), Gaps = 4/362 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRLP L+A+GAD++++S AT SVE M +IT R Y +GDL AWYA+ AT D Sbjct: 27 AQRRLPALVAAGADIRLVSPEATPSVEAMADAGEITWEQRPYAEGDLADAWYALIATSDT 86 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 A N A AE +R +++CVR+D A TA TPAT + G++V VL + Sbjct: 87 AANDAASAEGERHRVWCVRSDDADRATAWTPATGHSEGVTVAVLTTEARHRDPRHTAAIR 146 Query: 143 XXLQNGLVTSTSYQSSDVIRG-GVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXX 201 + GL T R GVAL+GGGPGDP+LITVRGRRLLA+ADVV+ADR Sbjct: 147 DAVVEGLRDGTLVAPHRRTRTPGVALVGGGPGDPDLITVRGRRLLAEADVVIADRLGPRD 206 Query: 202 XXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEV 261 HVEVIDAAKIPYGR MAQ+AIN+ +IE A+ G+ VVRLKGGDPFVF RG EE Sbjct: 207 LLAELPPHVEVIDAAKIPYGRFMAQEAINNALIEHARQGKAVVRLKGGDPFVFGRGMEEA 266 Query: 262 LACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNAL 321 A EAGI VVPG++S I+VP AG+PVTHR HEF VVSGH+APD SLV+W +L Sbjct: 267 QALAEAGIACTVVPGISSTISVPGAAGIPVTHRGVAHEFTVVSGHVAPDDERSLVDWPSL 326 Query: 322 AAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVR 381 A ++GT+V+LM V++I L+ G+ DTPV +VQ GTT AQ + ATLA E Sbjct: 327 AKLTGTLVILMGVDKIGKIAGTLIAHGKSPDTPVALVQEGTTAAQRRVDATLATVAEVAV 386 Query: 382 AE 383 AE Sbjct: 387 AE 388 >tr|B1W3D1|B1W3D1_STRGG Tax_Id=455632 SubName: Full=Putative uroporphyrin-III methyltransferase;[Streptomyces griseus subsp. griseus] Length = 427 Score = 345 bits (885), Expect = 6e-93 Identities = 194/362 (53%), Positives = 232/362 (64%), Gaps = 4/362 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRRLP LIA+GA + ++S SAT SVE M +I R Y DGDL WYA+ A+ D Sbjct: 33 AQRRLPQLIATGAVITLVSPSATPSVEAMADAGEIRWERRRYEDGDLADTWYALIASSDT 92 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 A N A AEA+R + +CVRAD A TA TPAT ++V VL + Sbjct: 93 AANDAASAEAERTRTWCVRADDAEAATAWTPATGRIDNITVAVLNTTPRGRDPRHSAALR 152 Query: 143 XXLQNGLVTSTSYQSSDVIRG-GVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXX 201 + GL T R GVAL+GGGPGDP+LITVRGRRLLA+ADVV+ADR Sbjct: 153 DAIVEGLRDGTLAAPHHRTRTPGVALVGGGPGDPDLITVRGRRLLAEADVVIADRLGPRD 212 Query: 202 XXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEV 261 HVEVIDAAKIPYGR MAQ+AIN +IE AKAG+ VVRLKGGDPFVF RG EE Sbjct: 213 LLDELPPHVEVIDAAKIPYGRFMAQEAINQALIEHAKAGKSVVRLKGGDPFVFGRGMEEA 272 Query: 262 LACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNAL 321 A GIP VVPG++S I+VP AG+PVTHR HEF VVSGH+AP+ P SLV+W A+ Sbjct: 273 QALAAEGIPCTVVPGISSTISVPGAAGIPVTHRGVAHEFTVVSGHVAPEDPRSLVDWEAI 332 Query: 322 AAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVR 381 A + GT+VLLMAV++I AL+ G+ TPV +VQ GTT AQ + ATLAD E+ Sbjct: 333 ARLRGTLVLLMAVDKIGAIAAALVAHGKDPATPVALVQEGTTAAQRRVDATLADVGERAV 392 Query: 382 AE 383 AE Sbjct: 393 AE 394 >tr|A1SJW9|A1SJW9_NOCSJ Tax_Id=196162 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Nocardioides sp.] Length = 407 Score = 339 bits (870), Expect = 3e-91 Identities = 180/361 (49%), Positives = 232/361 (64%), Gaps = 6/361 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRR+P LIA+GADV V+S T ++E M ++T R + D DL+ AWY +AATDD Sbjct: 27 AQRRVPHLIAAGADVHVVSPQVTPAIEGMVGSGEVTWHERGFADTDLDEAWYVVAATDDH 86 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 AVN + A+ R++FCVR+D A +A TPA HAG++V VL + Sbjct: 87 AVNEQVSDAAEARRVFCVRSDDASRASAWTPAVGRHAGVTVAVLGQREPRRSAAVRDEIL 146 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 L+ G + + + GV L+GGGPGDPEL+TV GR+ L +ADVVVADR Sbjct: 147 EGLREGTIVARHQRDRSA---GVVLVGGGPGDPELMTVAGRKALVEADVVVADRLAPREL 203 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VE+ID AK+P GR+ Q+ IN V+IERA+AG+ VVR KGGD FVF RG+EEV+ Sbjct: 204 LGELPADVELIDVAKLPRGRSALQEEINRVIIERARAGKRVVRFKGGDNFVFGRGFEEVI 263 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC EAG+PV VVPG+TS+IAVPA+AG+PVTHR HEF +VSGH+ P HP+S VNW AL Sbjct: 264 ACREAGVPVTVVPGLTSSIAVPAVAGIPVTHRGVAHEFTIVSGHLPPGHPQSQVNWTALG 323 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 A+ GT+VL+MAVE AL+ GGR TPV VV GT P + T+ ATL ++ Sbjct: 324 ALRGTVVLMMAVENAPRIATALVAGGRAGSTPVAVVCEGTMPGERTVLATLDTLATRLEE 383 Query: 383 E 383 E Sbjct: 384 E 384 >tr|C4EMJ6|C4EMJ6_STRRS Tax_Id=479432 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Streptosporangium roseum DSM 43021] Length = 410 Score = 337 bits (863), Expect = 2e-90 Identities = 185/360 (51%), Positives = 234/360 (65%), Gaps = 6/360 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 AQRR+P L+ +GA V ++S S T +++ + ++ R Y+ GD++GAW A TDD Sbjct: 24 AQRRVPALLDAGALVTIVSTSVTHALDDLIATGRVIWEARPYQVGDVDGAWLVQACTDDR 83 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 AVN A+ AEA+ ++I+CVRAD A TPA+ +SV V A GD Sbjct: 84 AVNTAVAAEAEAKRIWCVRADDKDASAAWTPASGQVDEISVAVTAGGDPRRAAGIRDAVV 143 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 L++G V + ++ V GVAL+GGGPGDP LITVRGR+LLAQADVV+ADR Sbjct: 144 GALRDGTVDARRNRTKPV---GVALVGGGPGDPGLITVRGRQLLAQADVVIADRLAPQAL 200 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VE+IDAAKIPYGR MAQ+ IN+++IE AK G+FVVRLKGGDPFVF RG EE+L Sbjct: 201 LDELSPDVELIDAAKIPYGRYMAQEKINELLIEHAKQGKFVVRLKGGDPFVFGRGGEEML 260 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC GIPVIVVPG+TS +AVPA A VPVTHR + EF V+S H+ P S V+W LA Sbjct: 261 ACAREGIPVIVVPGITSPVAVPAAANVPVTHRGVSQEFHVISVHVPPGDARSTVDWPNLA 320 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 GT+VL+MAVERI E L+ GR +TPV+VVQ GT P Q L ATL+ E+V A Sbjct: 321 RSGGTLVLMMAVERIGTIAETLIHDGRSPETPVMVVQDGTLPTQRALYATLSTVAERVTA 380 >tr|C0UBG8|C0UBG8_9ACTO Tax_Id=526225 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Geodermatophilus obscurus DSM 43160] Length = 419 Score = 330 bits (845), Expect = 3e-88 Identities = 177/353 (50%), Positives = 225/353 (63%), Gaps = 4/353 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 A RR+ L+ + A V V+S T ++E + +T R Y GDL+GAWYA+AATDDP Sbjct: 34 AHRRVAGLLEARARVTVVSPEVTPALEALVGPGAVTWVRRRYEAGDLDGAWYAVAATDDP 93 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 VNAA+ EA+R ++FC RAD + TPA L VGV GD Sbjct: 94 VVNAAVAEEAERSRVFCARADDRSASSVWTPAVGRQGDLVVGVHGGGDPQRAVGVRDAVL 153 Query: 143 XXLQNGLVTSTSYQSSDVIR-GGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXX 201 L +G + + + + R G V L+GGGPGDP LITVRG++ ++QADVV+AD Sbjct: 154 AGLTDGTIRDHAGREAPGGRPGSVVLVGGGPGDPGLITVRGQQAVSQADVVLADHLAPQS 213 Query: 202 XXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEV 261 VEVIDA+K+P GR MAQ+ IN +++E A+AG+ VVRLKGGDPFVF RG EE+ Sbjct: 214 LLASLPADVEVIDASKLPRGRYMAQEQINALLVEHARAGKRVVRLKGGDPFVFGRGMEEL 273 Query: 262 LACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNAL 321 AC AG+PV VVPGVTSAI VP LAG+PVTHR HEFVVVSGH+ P HP+SLV+W AL Sbjct: 274 EACVAAGVPVEVVPGVTSAIGVPGLAGIPVTHRGLTHEFVVVSGHVPPGHPQSLVDWAAL 333 Query: 322 AAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLA 374 + GTIV+LM V+ AL++ GR +TPV VV G+TP QH +R TLA Sbjct: 334 GRLRGTIVVLMGVDTAPAIAAALVEHGRAPETPVAVVADGSTPTQHAVRTTLA 386 >tr|Q47MR6|Q47MR6_THEFY Tax_Id=269800 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Thermobifida fusca] Length = 426 Score = 324 bits (831), Expect = 1e-86 Identities = 186/365 (50%), Positives = 235/365 (64%), Gaps = 20/365 (5%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGA---WYAIAAT 79 AQRR+P+L+ +GA V V+S T +++ + +I R YR GD+ G W AAT Sbjct: 23 AQRRVPVLLEAGARVTVVSPHVTTALQGLAESGRIHWEQRPYRRGDVTGLGRFWLVHAAT 82 Query: 80 DDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXX 139 DDP VNAA+VAEA+ +I+ V AD +A TPAT + +G++VGV+ D Sbjct: 83 DDPEVNAAVVAEAEEARIWSVHADDRHASSAWTPATGSASGVTVGVITGTD--------P 134 Query: 140 XXXXXLQNGLVTSTSYQSSDVIRG-----GVALIGGGPGDPELITVRGRRLLAQADVVVA 194 L++ +VT + + D RG GVAL+GGGPGDP LITVRGR+LLAQADVVV Sbjct: 135 RRAAGLRDAIVTGLADGTLDARRGRAPLRGVALVGGGPGDPGLITVRGRQLLAQADVVVV 194 Query: 195 DRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVF 254 DR VE+IDAAKIPYGR+M+Q+ IN V+++RA+ G+FVVRLKGGDPFVF Sbjct: 195 DRLAPTSLLDQLSGDVEIIDAAKIPYGRSMSQEGINAVIVDRARQGKFVVRLKGGDPFVF 254 Query: 255 ARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPES 314 RG EE+ AC AGIPV VVPGVTSA+A PA G+PVTHR F VVS H+AP S Sbjct: 255 GRGGEELAACVAAGIPVTVVPGVTSALAAPASVGIPVTHRGVAQHFHVVSAHVAPGDERS 314 Query: 315 LVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLA 374 VNW LA GTIV+LM VER+ EAL++ GR TP+ V+Q T P+Q TL ATL Sbjct: 315 TVNWETLARSGGTIVVLMGVERLGRIAEALIRYGRDPHTPIAVIQEATLPSQTTLVATL- 373 Query: 375 DTPEK 379 +T EK Sbjct: 374 ETVEK 378 >tr|C4RPH8|C4RPH8_9ACTO Tax_Id=219305 SubName: Full=Uroporphyrin-III C-methyltransferase;[Micromonospora sp. ATCC 39149] Length = 412 Score = 320 bits (821), Expect = 2e-85 Identities = 180/374 (48%), Positives = 229/374 (61%), Gaps = 26/374 (6%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEV---MDKITLTLREYRDGDLEGAWYAIAATDDP 82 A RR+P L+ +GADV ++S T ++ ++ R + DL+GAW AA +DP Sbjct: 10 ATRRVPALLDAGADVLLVSPELTPALRAHVDAGRLHWEPRRFVPDDLDGAWLVQAAVNDP 69 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 A A++ A A R+IFCVRAD TA TPA H ++V VL GD Sbjct: 70 AAAASVSAAAAERRIFCVRADDRAAATAWTPAVTRHGPVTVAVLGGGDPRRAMTVRNAIR 129 Query: 143 XXL--QNGLVTSTSYQ---------------------SSDVIRGGVALIGGGPGDPELIT 179 L + G + + S + ++D G VAL+G GPGDPELIT Sbjct: 130 DLLGARKGPLLTDSVEEGPPVNFPPAEGRGPAAGREPAADRAAGRVALVGAGPGDPELIT 189 Query: 180 VRGRRLLAQADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKA 239 V+G RLL +ADVVVADR VE++DA+KIPYG + AQ+ IN ++++RA A Sbjct: 190 VKGWRLLTEADVVVADRLVPGLLLDELRPDVELVDASKIPYGPSRAQEEINRILVDRALA 249 Query: 240 GRFVVRLKGGDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHE 299 G FVVRLKGGDP+VF RG EE+LAC AG+PV VVPGVTS+IA PA AGVPVTHRA HE Sbjct: 250 GAFVVRLKGGDPYVFGRGGEELLACAAAGVPVTVVPGVTSSIAAPAAAGVPVTHRAVAHE 309 Query: 300 FVVVSGHIAPDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQ 359 F VVSGH+APD P SLV W+ALA + GT+V+LM ++ + E L GRPADTPV VVQ Sbjct: 310 FTVVSGHVAPDSPASLVRWDALAGLRGTLVILMGLKNLAAITETLTAYGRPADTPVAVVQ 369 Query: 360 HGTTPAQHTLRATL 373 GTT Q +LR+TL Sbjct: 370 EGTTGDQRSLRSTL 383 >tr|C4DDE0|C4DDE0_9ACTO Tax_Id=446470 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Stackebrandtia nassauensis DSM 44728] Length = 395 Score = 319 bits (817), Expect = 4e-85 Identities = 178/353 (50%), Positives = 217/353 (61%), Gaps = 4/353 (1%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 A RR+P L+ +GADV ++S A S+ M ++ R ++ DL+GAW +AATDDP Sbjct: 23 AHRRVPRLLDAGADVLLVSPHARDSLRAMASEHRLRWEERRFQASDLDGAWLVLAATDDP 82 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 AVNA I A A+ ++FCVRAD TA TPA H L+ A GD Sbjct: 83 AVNAEISALAEEARVFCVRADDREAATAWTPAVGQHEELTFAAFAGGDPRRAAALRDRLL 142 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 G V+ ++ S I G VAL+G GPGDP+LITV GR LAQADVV+ADR Sbjct: 143 ELAATGEVSPPRFRGSGTIPG-VALVGAGPGDPDLITVAGRAALAQADVVIADRLAPARL 201 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 E+IDAAKIPYGR QD I +M+ERAK G+FVVRLKGGD FVF RG EE+ Sbjct: 202 LEELRDETELIDAAKIPYGRQREQDEIIALMLERAKNGKFVVRLKGGDGFVFGRGGEELD 261 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC AGIPV V+PGVTSAIA PALA +PVT R HEF +VSGH+AP P SL NW+ALA Sbjct: 262 ACAAAGIPVRVIPGVTSAIAGPALASIPVTERGLVHEFTIVSGHVAPGDPTSLTNWDALA 321 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLAD 375 + GT+V+LM V AL+ GGR A TP VV +TP Q +R TLA+ Sbjct: 322 RLRGTVVVLMGVRHRGAIAAALIAGGRDAGTPAAVVMDASTPRQREVRTTLAE 374 >tr|C1YQA3|C1YQA3_NOCDA Tax_Id=446468 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length = 418 Score = 318 bits (816), Expect = 6e-85 Identities = 178/365 (48%), Positives = 230/365 (63%), Gaps = 11/365 (3%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGA-----WYAIA 77 AQRR+P+LI +GA V ++S A+ ++E + ++T R Y GD+ G W A Sbjct: 15 AQRRVPVLIEAGARVTLVSPEASAALEDLASAGRLTWHRRPYAPGDVAGPDAPAHWLVHA 74 Query: 78 ATDDPAVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXX 137 ATDDP VNAA+ EA+ +++CVRAD +A TPA+ + AG++VGV+ASGD Sbjct: 75 ATDDPRVNAAVAEEAENARVWCVRADDRHASSAWTPASGSAAGVTVGVVASGDPRRSAGL 134 Query: 138 XXXXXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRX 197 L +G T + + + +RG VAL+GGGPGDP LITVRG++LL+QADVVV DR Sbjct: 135 RDAVVDGLADG--TLDARRGRERLRG-VALVGGGPGDPGLITVRGQQLLSQADVVVVDRL 191 Query: 198 XXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARG 257 VE++DAAKIPYGR+M Q+ IN +++RA G+FVVRLKGGD F+F RG Sbjct: 192 APTSLLDRLPADVEIVDAAKIPYGRSMTQEEINATLVDRAGRGKFVVRLKGGDSFLFGRG 251 Query: 258 YEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVN 317 EE AC AGIPVI VPGVTSA+A PA AG+P THR + +VS H+ P S V+ Sbjct: 252 GEEAAACAAAGIPVIAVPGVTSALAAPASAGIPATHRGVAQDLHIVSAHVPPGDGRSTVD 311 Query: 318 WNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTP 377 W LA GT+V+LM VERIE EAL+ GR ADTPV VVQ T P Q T+ TLA Sbjct: 312 WAGLARAGGTVVVLMGVERIEAIAEALVSHGRSADTPVAVVQEATLPGQRTVTGTLATIA 371 Query: 378 EKVRA 382 R+ Sbjct: 372 AAARS 376 >tr|A4XAM7|A4XAM7_SALTO Tax_Id=369723 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Salinispora tropica] Length = 417 Score = 311 bits (797), Expect = 9e-83 Identities = 177/372 (47%), Positives = 221/372 (59%), Gaps = 15/372 (4%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEV---MDKITLTLREYRDGDLEGAWYAIAATDDP 82 A RR+P L+ +GADV +++ T ++ ++ R + DL+GAW A DDP Sbjct: 26 ATRRMPALLDAGADVLLVAPELTPALRAHADAGRLRWERRRFAVDDLDGAWLVQVAVDDP 85 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 + AAI AD R+IFCVRAD TA TPA ++V VL GD Sbjct: 86 SAAAAISTVADERRIFCVRADDRAAATAWTPAVTRQGPVTVAVLGGGDPRRAMAVRDAVR 145 Query: 143 XXLQNGL-----------VTSTSYQSSDVIRGG-VALIGGGPGDPELITVRGRRLLAQAD 190 L G + RGG VAL+G GPGDPELITV+GRRLL +A+ Sbjct: 146 DLLAAGPGPLDPPPADAGARGVPGPARPTRRGGHVALVGAGPGDPELITVKGRRLLTEAE 205 Query: 191 VVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGD 250 VVVADR VE++DAAKIPYG A AQ+ IN ++++RA AGR VVRLKGGD Sbjct: 206 VVVADRLVPGLLLDELRPEVELVDAAKIPYGPARAQEEINQILVDRALAGRSVVRLKGGD 265 Query: 251 PFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPD 310 P+VF RG EE+LAC AG+PV VVPGVTSAIA A AGVPVTHRA HEF VVSGH++PD Sbjct: 266 PYVFGRGGEELLACAGAGVPVTVVPGVTSAIAAAAGAGVPVTHRAVAHEFTVVSGHVSPD 325 Query: 311 HPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLR 370 S+V W LA + GT+V+LM ++ + L+ GRPA TP +VVQ GTT AQ T+R Sbjct: 326 SSASMVRWEHLAGLRGTLVILMGLKNLAAISATLVTYGRPAQTPAVVVQEGTTGAQRTIR 385 Query: 371 ATLADTPEKVRA 382 +TL V A Sbjct: 386 STLGVVAADVTA 397 >tr|A8M1Q0|A8M1Q0_SALAI Tax_Id=391037 SubName: Full=Uroporphyrin-III C-methyltransferase;[Salinispora arenicola] Length = 419 Score = 311 bits (796), Expect = 1e-82 Identities = 176/374 (47%), Positives = 221/374 (59%), Gaps = 17/374 (4%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEV---MDKITLTLREYRDGDLEGAWYAIAATDDP 82 A RR+P L+ +GADV +++ T ++ ++ R + DL+GAW A +DP Sbjct: 26 ATRRVPALLDAGADVLLVAPELTPALRAHADAGRLHWARRRFAVDDLDGAWLVQVAVNDP 85 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 AA+ A A R+IFCVRAD TA TPA ++V VL GD Sbjct: 86 IAAAAVSAAAGERRIFCVRADDRAAATAWTPAVTRQGPVTVAVLGGGDPRRAMAVRDAVR 145 Query: 143 XXLQ-------------NGLVTSTSYQSSDVIRGG-VALIGGGPGDPELITVRGRRLLAQ 188 L +G + S RGG VAL+G GPGDPELITV+GRRLL + Sbjct: 146 DLLAAGAGPLAPPSTTGDGTAGAPGRAPSTTARGGRVALVGAGPGDPELITVKGRRLLTE 205 Query: 189 ADVVVADRXXXXXXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKG 248 ADVVVADR VE++DAAKIPYG A AQ+ IN V+++RA AG+ VVRLKG Sbjct: 206 ADVVVADRLVPGLLLDELRPEVELVDAAKIPYGPARAQEEINRVLVDRALAGKAVVRLKG 265 Query: 249 GDPFVFARGYEEVLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIA 308 GDP+VF RG EE+LAC AG+PV VV GVTSAIA PA AGVPVTHRA HEF VVSGH+ Sbjct: 266 GDPYVFGRGGEELLACAAAGVPVTVVSGVTSAIAAPAGAGVPVTHRAVAHEFTVVSGHVP 325 Query: 309 PDHPESLVNWNALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHT 368 PD P S+V W LA + GT+ ++M ++ + L+ GRPADTP +VVQ GTT Q T Sbjct: 326 PDSPASMVRWEHLAGLRGTLAIMMGLKNLGAISATLVTHGRPADTPAVVVQEGTTGDQRT 385 Query: 369 LRATLADTPEKVRA 382 +R+TL V A Sbjct: 386 VRSTLGGVAVDVAA 399 >tr|C1RJY7|C1RJY7_9CELL Tax_Id=446466 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Cellulomonas flavigena DSM 20109] Length = 406 Score = 256 bits (655), Expect = 3e-66 Identities = 151/353 (42%), Positives = 196/353 (55%), Gaps = 12/353 (3%) Query: 26 AQRRLPLLIASGADVQVISRSATRSVEVM---DKITLTLREYRDGDLEGAWYAIAATDDP 82 A RR ++A G DV V++ + + + +T R+Y GDL+GAW AT + Sbjct: 26 AARRARGMLADGGDVHVVAPALCEDLADLAATGALTWHARQYVRGDLDGAWLVHTATGER 85 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXX 142 + A+ A+A+ + +CVRAD A TA TPA ++V V A GD Sbjct: 86 RADDAVAADAEAARTWCVRADDASASTAWTPAVARAGDVTVAVNAGGDPRRAVALRSALQ 145 Query: 143 XXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXX 202 L G + + G V L+GGGPGDP LIT RGRR LA+ADVVV DR Sbjct: 146 VQLDTGALPLRHRRPGP---GHVTLVGGGPGDPGLITTRGRRALAEADVVVVDRLAPRAL 202 Query: 203 XXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVL 262 VEV++A K P+ + Q IN +++ERA+AG+ VVRLKGGDPFV RG EE+ Sbjct: 203 LDELEPDVEVVEAGKAPHAHTLTQAEINALLVERARAGQRVVRLKGGDPFVLGRGSEELA 262 Query: 263 ACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALA 322 AC EAG+ V VVPGVTSAIAVP AGVPVTHR + +VS H A +W LA Sbjct: 263 ACLEAGVDVAVVPGVTSAIAVPGAAGVPVTHRDVARQVTIVSAHDAD------TDWETLA 316 Query: 323 AMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLAD 375 + GT+VLLM V R++ + L+ G TPV VV+ GT P Q T T+AD Sbjct: 317 RLRGTLVLLMGVSRLDEHMALLVSHGLDPATPVAVVEKGTLPTQRTTLGTVAD 369 >tr|A6W7M5|A6W7M5_KINRD Tax_Id=266940 SubName: Full=Uroporphyrin-III C-methyltransferase;[Kineococcus radiotolerans] Length = 421 Score = 247 bits (631), Expect = 2e-63 Identities = 145/351 (41%), Positives = 195/351 (55%), Gaps = 11/351 (3%) Query: 26 AQRRLPLLIASGADVQVISRSATRSV-EVMDKITLTLREYRDGDLEGAWYAIAATDDPAV 84 A RR L+A+GADV V++ + + +++ +T RE D+ AW AT DP Sbjct: 33 AARRARDLVAAGADVLVVAPAVCEDLRDLLPDLTWEQREVEPRDVADAWLVHTATGDPRA 92 Query: 85 NAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXX 144 +A + A A+ +++CVRAD A +A TP+ G++V V A GD Sbjct: 93 DAEVAAAAEALRVWCVRADDARASSAWTPSVVRREGVTVSVTAGGDPRRARGLREALSRW 152 Query: 145 LQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXX 204 L +G + G V L+GGGPG+ +L+T+RGRR LA+ADVVV DR Sbjct: 153 LDSGAAPLRRRRPG---AGRVTLVGGGPGEVDLLTLRGRRRLAEADVVVVDRLAPTAVLD 209 Query: 205 XXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLAC 264 V+V+D K P + Q+ IN +++E A+AGR VVRLKGGD +V RG EEVLAC Sbjct: 210 ELDPDVQVVDVGKTPDHHPVPQEEINRILVEHARAGRRVVRLKGGDSYVLGRGGEEVLAC 269 Query: 265 TEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAM 324 AG+ V VVPGVTSA AVPA AG+PVTHR + VVSGH V+ LA + Sbjct: 270 RAAGVEVEVVPGVTSAFAVPAAAGIPVTHRGLSRSVTVVSGH-------EDVDAATLARL 322 Query: 325 SGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLAD 375 GT+V LM V + L+ G+PA TPV +V++G P Q T R TL D Sbjct: 323 DGTVVFLMGVTMLPRLCADLVAAGKPASTPVAIVENGWRPDQRTTRGTLGD 373 >tr|C8XJG0|C8XJG0_NAKMY Tax_Id=479431 SubName: Full=Uroporphyrin-III C-methyltransferase;[Nakamurella multipartita] Length = 416 Score = 243 bits (620), Expect = 3e-62 Identities = 146/363 (40%), Positives = 201/363 (55%), Gaps = 10/363 (2%) Query: 26 AQRRLPLLIASGADVQVISRSATRSV---EVMDKITLTLREYRDGDLEGAWYAIAATDDP 82 A R++ + +GADV V++ A S+ E +T EY GDL+GAW AAT + Sbjct: 36 AARKVAGCLDAGADVLVVAPFACESIVADEAAGLLTWRCAEYTTGDLDGAWLVFAATGER 95 Query: 83 AVNAAIVAEADRRQIFCVRADIAVEGTAVTPATFNHAGL--SVGVLASGDHXXXXXXXXX 140 A + A+ A+A+ ++FCVRAD A G+A + A + SVG + D Sbjct: 96 ATDDAVAADAEAARVFCVRADDAALGSARSAAVIRRDDVLVSVGSADAADPRRAVAVRDA 155 Query: 141 XXXXLQNGLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXX 200 L G + + G V L+GGGPGD +L+T+RGRR LA ADVVV DR Sbjct: 156 ITHGLDTGALPVRRQRGGP---GRVVLVGGGPGDGDLLTLRGRRELAAADVVVIDRLAPR 212 Query: 201 XXXXXXXXHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEE 260 V V++ K P + Q IN +++E A+AGR VVRLKGGDPF+F RG EE Sbjct: 213 SVIDELGPGVLVLEVGKAPGRHPVPQPEINRLLVEHAQAGRRVVRLKGGDPFLFGRGGEE 272 Query: 261 VLACTEAGIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGH--IAPDHPESLVNW 318 V AC EAG+ V V+PGVTSA AVPA AG+PVTHR + + V++GH ++P + ++W Sbjct: 273 VAACREAGVEVSVIPGVTSAFAVPAAAGIPVTHRGQSRQVTVITGHDAVSPGGLPADLDW 332 Query: 319 NALAAMSGTIVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPE 378 ALA GT+V+LM V + LL G TPV +V++G TPAQ L + + Sbjct: 333 AALARGRGTLVVLMGVAALPTIRAGLLGAGMDPATPVAIVENGWTPAQRVTTGALDEIAD 392 Query: 379 KVR 381 + R Sbjct: 393 RAR 395 >tr|A0LVC8|A0LVC8_ACIC1 Tax_Id=351607 SubName: Full=Uroporphyrinogen-III C-methyltransferase; EC=2.1.1.107;[Acidothermus cellulolyticus] Length = 475 Score = 242 bits (618), Expect = 5e-62 Identities = 145/355 (40%), Positives = 190/355 (53%), Gaps = 10/355 (2%) Query: 28 RRLPLLIASGADVQVISRSATRSVEVMDKITLTLREYRDGDLEGAWYAIAATDDPAVNAA 87 RR +G V VI+ + + +I R Y+ GD+ GAW A T P V+ A Sbjct: 27 RRAIAAADAGGRVDVIAPDISPELASDQRIRTFRRAYQPGDVAGAWLVHACTGVPDVDDA 86 Query: 88 IVAEADRRQIFCVRADIAVEGTAVTPATFNHAGLSVGVLASGDHXXXXXXXXXXXXXLQN 147 + AEA+ +I+ VRA A +A PA +++ V A GD L Sbjct: 87 VCAEAEAARIWYVRAADAAHSSAAVPAVARVDDVTIAVNAGGDPCRARVLRDAVQLALNT 146 Query: 148 GLVTSTSYQSSDVIRGGVALIGGGPGDPELITVRGRRLLAQADVVVADRXXXXXXXXXXX 207 G + +++ G VAL+GGGPGDPELITVRGRRLLA+ADVVV DR Sbjct: 147 GALPLRRHRAH---AGRVALVGGGPGDPELITVRGRRLLAEADVVVTDRLGPRALLAELP 203 Query: 208 XHVEVIDAAKIPYGRAMAQDAINDVMIERAKAGRFVVRLKGGDPFVFARGYEEVLACTEA 267 VEVID K Q IN++++ A+ G+FVVRLKGGDPFV RG EE+ AC A Sbjct: 204 SGVEVIDVGKARDHHTRTQSEINELLVSLARQGKFVVRLKGGDPFVLGRGGEELAACMAA 263 Query: 268 GIPVIVVPGVTSAIAVPALAGVPVTHRATNHEFVVVSGHIAPDHPESLVNWNALAAMSGT 327 G+P VVPGVTSAIAVPA AG+PVT R F V+SGH V+W ++ GT Sbjct: 264 GVPCEVVPGVTSAIAVPASAGIPVTQRGVARHFTVLSGH-------DDVDWRSVVGAGGT 316 Query: 328 IVLLMAVERIELFVEALLKGGRPADTPVLVVQHGTTPAQHTLRATLADTPEKVRA 382 +V+LM V RI+ + L+ G TP VV++GT P Q AT+ + +A Sbjct: 317 LVILMGVSRIDQIAKELVAAGLDESTPAAVVENGTLPHQRVTIATVGTIAPRAQA 371 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.319 0.135 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 2,415,236,835 Number of extensions: 91034134 Number of successful extensions: 290487 Number of sequences better than 10.0: 4571 Number of HSP's gapped: 287421 Number of HSP's successfully gapped: 4956 Length of query: 401 Length of database: 3,846,993,858 Length adjustment: 140 Effective length of query: 261 Effective length of database: 2,268,465,438 Effective search space: 592069479318 Effective search space used: 592069479318 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 81 (35.8 bits)