BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_2233
         (544 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|B2HP78|B2HP78_MYCMM Tax_Id=216594 (fadD12)SubName: Full=Long-...  1012   0.0  
tr|Q7U037|Q7U037_MYCBO Tax_Id=1765 (fadD12)SubName: Full=POSSIBL...   843   0.0  
tr|O06831|O06831_MYCTU Tax_Id=1773 (fadD12)SubName: Full=POSSIBL...   843   0.0  
tr|C6DTF6|C6DTF6_MYCTK Tax_Id=478434 SubName: Full=Long-chain fa...   843   0.0  
tr|C1AN72|C1AN72_MYCBT Tax_Id=561275 (fadD12)SubName: Full=Acyl-...   843   0.0  
tr|A5U2C9|A5U2C9_MYCTA Tax_Id=419947 (fadD12)SubName: Full=Fatty...   843   0.0  
tr|A1KIL6|A1KIL6_MYCBP Tax_Id=410289 (fadD12)SubName: Full=Possi...   843   0.0  
tr|A5WMB0|A5WMB0_MYCTF Tax_Id=336982 SubName: Full=Long-chain fa...   843   0.0  
tr|A4KGY1|A4KGY1_MYCTU Tax_Id=395095 SubName: Full=Long-chain-fa...   843   0.0  
tr|A2VHV4|A2VHV4_MYCTU Tax_Id=348776 SubName: Full=Long-chain-fa...   843   0.0  
tr|Q741D2|Q741D2_MYCPA Tax_Id=1770 (fadD12)SubName: Full=FadD12_...   820   0.0  
tr|A0QP81|A0QP81_MYCS2 Tax_Id=246196 SubName: Full=Acyl-CoA synt...   776   0.0  
tr|A1T1N1|A1T1N1_MYCVP Tax_Id=350058 SubName: Full=AMP-dependent...   762   0.0  
tr|A4T3U7|A4T3U7_MYCGI Tax_Id=350054 SubName: Full=AMP-dependent...   760   0.0  
tr|A3Q422|A3Q422_MYCSJ Tax_Id=164757 SubName: Full=AMP-dependent...   746   0.0  
tr|Q1B5H0|Q1B5H0_MYCSS Tax_Id=164756 SubName: Full=AMP-dependent...   738   0.0  
tr|A1UJL6|A1UJL6_MYCSK Tax_Id=189918 SubName: Full=AMP-dependent...   738   0.0  
tr|A3Q319|A3Q319_MYCSJ Tax_Id=164757 SubName: Full=AMP-dependent...   738   0.0  
tr|A1TCV2|A1TCV2_MYCVP Tax_Id=350058 SubName: Full=AMP-dependent...   734   0.0  
tr|A0QHZ3|A0QHZ3_MYCA1 Tax_Id=243243 SubName: Full=Acyl-CoA synt...   725   0.0  
tr|A4T888|A4T888_MYCGI Tax_Id=350054 SubName: Full=AMP-dependent...   724   0.0  
tr|D0L3A2|D0L3A2_GORB4 Tax_Id=526226 SubName: Full=AMP-dependent...   534   e-149
tr|A1SI70|A1SI70_NOCSJ Tax_Id=196162 SubName: Full=AMP-dependent...   432   e-119
tr|A4F991|A4F991_SACEN Tax_Id=405948 (fadD12)SubName: Full=Acyl-...   415   e-114
tr|C7MQ92|C7MQ92_SACVD Tax_Id=471857 SubName: Full=Acyl-CoA synt...   412   e-113
tr|C1YR46|C1YR46_NOCDA Tax_Id=446468 SubName: Full=Acyl-CoA synt...   406   e-111
tr|Q5YYK7|Q5YYK7_NOCFA Tax_Id=37329 SubName: Full=Putative acyl-...   403   e-110
tr|D1A3M5|D1A3M5_THECU Tax_Id=471852 SubName: Full=AMP-dependent...   398   e-109
tr|C1AJU6|C1AJU6_MYCBT Tax_Id=561275 (fadD2)SubName: Full=Acyl-C...   398   e-108
tr|A1KF91|A1KF91_MYCBP Tax_Id=410289 (fadD2)SubName: Full=Probab...   398   e-108
tr|Q7U2E6|Q7U2E6_MYCBO Tax_Id=1765 (fadD2)SubName: Full=PROBABLE...   397   e-108
tr|P95227|P95227_MYCTU Tax_Id=1773 (fadD2)SubName: Full=PROBABLE...   397   e-108
tr|C6DRS8|C6DRS8_MYCTK Tax_Id=478434 SubName: Full=Fatty-acid-Co...   397   e-108
tr|A5TYZ6|A5TYZ6_MYCTA Tax_Id=419947 (fadD2)SubName: Full=Fatty-...   397   e-108
tr|A5WIX8|A5WIX8_MYCTF Tax_Id=336982 SubName: Full=Fatty-acid-Co...   397   e-108
tr|A4KNT6|A4KNT6_MYCTU Tax_Id=395095 SubName: Full=Fatty-acid-Co...   397   e-108
tr|A2VNI4|A2VNI4_MYCTU Tax_Id=348776 SubName: Full=Fatty-acid-Co...   397   e-108
tr|Q5YT49|Q5YT49_NOCFA Tax_Id=37329 SubName: Full=Putative acyl-...   392   e-107
tr|C4DGK4|C4DGK4_9ACTO Tax_Id=446470 SubName: Full=Acyl-CoA synt...   388   e-105
tr|C4RJJ4|C4RJJ4_9ACTO Tax_Id=219305 SubName: Full=Acyl-CoA synt...   385   e-105
tr|D1A6A1|D1A6A1_THECU Tax_Id=471852 SubName: Full=AMP-dependent...   383   e-104
tr|Q9CD27|Q9CD27_MYCLE Tax_Id=1769 (fadD2)SubName: Full=Acyl-CoA...   381   e-103
tr|B8ZTD6|B8ZTD6_MYCLB Tax_Id=561304 (fadD2)SubName: Full=Acyl-C...   381   e-103
tr|Q0S2R2|Q0S2R2_RHOSR Tax_Id=101510 SubName: Full=Probable O-su...   380   e-103
tr|B2HNV0|B2HNV0_MYCMM Tax_Id=216594 (fadD2)SubName: Full=Fatty-...   380   e-103
tr|A0PN48|A0PN48_MYCUA Tax_Id=362242 (fadD2)SubName: Full=Fatty-...   379   e-103
tr|A3THW2|A3THW2_9MICO Tax_Id=313589 SubName: Full=Putative Acyl...   379   e-103
tr|C0ZX64|C0ZX64_RHOE4 Tax_Id=234621 SubName: Full=Putative fatt...   379   e-103
tr|C3JKR9|C3JKR9_RHOER Tax_Id=596309 SubName: Full=Acyl-CoA synt...   379   e-103
tr|C1B1K5|C1B1K5_RHOOB Tax_Id=632772 SubName: Full=Putative acid...   378   e-102

>tr|B2HP78|B2HP78_MYCMM Tax_Id=216594 (fadD12)SubName:
           Full=Long-chain-fatty-acid--CoA ligase
           FadD12;[Mycobacterium marinum]
          Length = 544

 Score = 1012 bits (2617), Expect = 0.0
 Identities = 515/544 (94%), Positives = 515/544 (94%)

Query: 1   MAPRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGL 60
           MAPRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGM          QRCPDRPGL
Sbjct: 1   MAPRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMGFTAGFAAAAQRCPDRPGL 60

Query: 61  VDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILL 120
           VDELGTLTWRQLDERSN           GSPKVVGIMCRNHRGFVEALVAANRIGADILL
Sbjct: 61  VDELGTLTWRQLDERSNALAAALQALPAGSPKVVGIMCRNHRGFVEALVAANRIGADILL 120

Query: 121 LNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQL 180
           LNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQL
Sbjct: 121 LNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQL 180

Query: 181 VNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIV 240
           VNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKH        TLKAILDRTPWRAEQPIV
Sbjct: 181 VNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHSGGSGGIGTLKAILDRTPWRAEQPIV 240

Query: 241 IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL 300
           IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL
Sbjct: 241 IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL 300

Query: 301 PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR 360
           PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR
Sbjct: 301 PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR 360

Query: 361 AAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSG 420
           AAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSG
Sbjct: 361 AAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSG 420

Query: 421 DVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRL 480
           DVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRL
Sbjct: 421 DVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRL 480

Query: 481 AAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAK 540
           AAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAK
Sbjct: 481 AAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAK 540

Query: 541 VCGT 544
           VCGT
Sbjct: 541 VCGT 544


>tr|Q7U037|Q7U037_MYCBO Tax_Id=1765 (fadD12)SubName: Full=POSSIBLE
           LONG-CHAIN-FATTY-ACID--COA LIGASE FADD12 (FATTY-ACID-COA
           SYNTHETASE) (FATTY-ACID-COA SYNTHASE);
           EC=6.2.1.-;[Mycobacterium bovis]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|O06831|O06831_MYCTU Tax_Id=1773 (fadD12)SubName: Full=POSSIBLE
           LONG-CHAIN-FATTY-ACID--CoA LIGASE FADD12 (FATTY-ACID-CoA
           SYNTHETASE) (FATTY-ACID-COA SYNTHASE); EC=6.2.1.-;
           SubName: Full=Substrate--CoA ligase,
           putative;[Mycobacterium tuberculosis]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|C6DTF6|C6DTF6_MYCTK Tax_Id=478434 SubName: Full=Long-chain
           fatty-acid-CoA ligase fadD12;[Mycobacterium
           tuberculosis]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|C1AN72|C1AN72_MYCBT Tax_Id=561275 (fadD12)SubName: Full=Acyl-CoA
           synthetase; EC=2.3.1.86;[Mycobacterium bovis]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|A5U2C9|A5U2C9_MYCTA Tax_Id=419947 (fadD12)SubName:
           Full=Fatty-acid-CoA ligase FadD12;[Mycobacterium
           tuberculosis]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|A1KIL6|A1KIL6_MYCBP Tax_Id=410289 (fadD12)SubName: Full=Possible
           long-chain-fatty-acid--CoA ligase fadD12;
           EC=6.2.1.-;[Mycobacterium bovis]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|A5WMB0|A5WMB0_MYCTF Tax_Id=336982 SubName: Full=Long-chain
           fatty-acid-CoA ligase fadD12;[Mycobacterium
           tuberculosis]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|A4KGY1|A4KGY1_MYCTU Tax_Id=395095 SubName:
           Full=Long-chain-fatty-acid-CoA ligase
           fadD12;[Mycobacterium tuberculosis str. Haarlem]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|A2VHV4|A2VHV4_MYCTU Tax_Id=348776 SubName:
           Full=Long-chain-fatty-acid-CoA ligase
           fadD12;[Mycobacterium tuberculosis C]
          Length = 535

 Score =  843 bits (2178), Expect = 0.0
 Identities = 424/538 (78%), Positives = 465/538 (86%), Gaps = 6/538 (1%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q  GLI T+ R+GLIAP+RPDRYL+I AAMRREGM          +RCPDRPGL+DE
Sbjct: 2   RIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDE 61

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LGTLTWRQLDER N           G P+VVGIMCRNHRGFV+AL+A NRIGA ILLLNT
Sbjct: 62  LGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNT 121

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
           +FAGPALA+VV REGVDTV+YDEEF+ATVDRA   +PQATRIVAW+D  HDLTVE+LV A
Sbjct: 122 SFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAA 181

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
           H G +PE TG  G++ILLTSGTTGTPKGA+H        TLKAILDRTPWRAE+  VIVA
Sbjct: 182 HAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIG--TLKAILDRTPWRAEEVTVIVA 239

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFHAWGFSQLVLA+SLACTIVTRR+FDPEATLDLIDRH ATGLVVVPVMFDRIM+LP +
Sbjct: 240 PMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAE 299

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
           + NRY GR+LRFAAASGSRMRPDVV+AFM++FGDVIYNNYNATEAGMIATATPADLR AP
Sbjct: 300 IRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAP 359

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRPAEGTEIRILDQ+F EVP GEVG+I+V NDSQFDGYTSG  KDFHAGFMSSGDVG
Sbjct: 360 DTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVG 419

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           YLD NGRLFVVGRDDEMIVSGGEN+YPIEVEKTLATHP+VAEAAVIGVDD+QYGQRLAAF
Sbjct: 420 YLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAF 479

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
           VVL+P      +A PETLKQHVRDNLANYKVPR+IAVLDELPRG TGKILR ELQ++V
Sbjct: 480 VVLKPGV----SATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRV 533


>tr|Q741D2|Q741D2_MYCPA Tax_Id=1770 (fadD12)SubName:
           Full=FadD12_1;[Mycobacterium paratuberculosis]
          Length = 539

 Score =  820 bits (2119), Expect = 0.0
 Identities = 413/539 (76%), Positives = 460/539 (85%), Gaps = 4/539 (0%)

Query: 5   IDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDEL 64
           + + LGLI T+ R+ L+APMRPDRYL+IAAAMRREGM          QRCPDRPGLVDE 
Sbjct: 5   VRETLGLIATMRRARLLAPMRPDRYLRIAAAMRREGMGMTSGFAAAAQRCPDRPGLVDER 64

Query: 65  GTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTA 124
           G+LTWRQLDER +           G+P V+GIMCRNHRGFVEALVAA+RIGADI+LLNT+
Sbjct: 65  GSLTWRQLDERCDALAAALQALQSGAPAVIGIMCRNHRGFVEALVAADRIGADIVLLNTS 124

Query: 125 FAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNAH 184
           FAGPALADV+ REGV+ VIYDEEFTATVDRA  GRP A RIVAW+D +H  TV++L+ + 
Sbjct: 125 FAGPALADVITREGVNAVIYDEEFTATVDRALAGRPDAIRIVAWTDTEHQHTVDKLIASK 184

Query: 185 LGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAP 244
            G +P RTGR G++ILLTSGTTGTPKGAK         TLKAILDRTPWRAE+P+VIVAP
Sbjct: 185 AGARPIRTGRKGKMILLTSGTTGTPKGAKQSGGNAGIGTLKAILDRTPWRAEEPVVIVAP 244

Query: 245 MFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKV 304
           MFHAWGFSQL+LAAS AC ++TRRKFDPEATLDLIDRHRATGLVVVPVMFDRIM+LP +V
Sbjct: 245 MFHAWGFSQLLLAASFACPVITRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMDLPAEV 304

Query: 305 LNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPD 364
             RY  R+LRFAAASGSRMRPDVVVAFM+ FGDVIYNNYNATEAGMIATATPADLRAAPD
Sbjct: 305 RRRYECRSLRFAAASGSRMRPDVVVAFMDEFGDVIYNNYNATEAGMIATATPADLRAAPD 364

Query: 365 TAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGY 424
           TAGRPA GTEIRILD EFNE+P GEVG+I+V N++QFDGYTSG++KDFH GFMSSGD+GY
Sbjct: 365 TAGRPAGGTEIRILDPEFNELPAGEVGTIYVRNNTQFDGYTSGSSKDFHEGFMSSGDLGY 424

Query: 425 LDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFV 484
           LD  GRLFVVGRDDEMIVSGGENVYPIEVEKTLATHP+VAEAAVIGVDDEQYGQRLAAFV
Sbjct: 425 LDSAGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPDVAEAAVIGVDDEQYGQRLAAFV 484

Query: 485 VLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKVCG 543
           VL P+A       PE LKQHVRDNLANYKVPREI+VLDELPR STGKILRA+L+A+V G
Sbjct: 485 VLAPEA----RTTPEALKQHVRDNLANYKVPREISVLDELPRSSTGKILRADLRARVGG 539


>tr|A0QP81|A0QP81_MYCS2 Tax_Id=246196 SubName: Full=Acyl-CoA
           synthase;[Mycobacterium smegmatis]
          Length = 543

 Score =  776 bits (2003), Expect = 0.0
 Identities = 396/543 (72%), Positives = 447/543 (82%), Gaps = 11/543 (2%)

Query: 3   PRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVD 62
           P ID + G++TT+ R+GLIAP+RPD+YL+I AAM RE M          QRCPDRPGLVD
Sbjct: 10  PLIDTV-GMVTTMRRAGLIAPLRPDKYLRIVAAMARENMSVTSGFASAAQRCPDRPGLVD 68

Query: 63  ELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLN 122
           ELGTLTWR++D++++           G+P+V+GIM RNHRGFV +L+AANRIGAD+LLLN
Sbjct: 69  ELGTLTWREIDQQADALAAGLQALSGGAPRVLGIMARNHRGFVLSLIAANRIGADVLLLN 128

Query: 123 TAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQA-TRIVAWSD-GQHDLTVEQL 180
           T+F+GPALA+VV+RE VD VIYDEEFT TVDRA  G P+A TRIVAW+D   HD+TV  L
Sbjct: 129 TSFSGPALAEVVSREKVDAVIYDEEFTDTVDRALAGAPEAPTRIVAWTDTAAHDVTVAAL 188

Query: 181 VNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIV 240
                G QP+R G+  ++ILLTSGTTGTPKGAKH         LKAILDRTPWRAE+P+V
Sbjct: 189 TEKFAGRQPQRGGQKSKVILLTSGTTGTPKGAKHSGGGPEI--LKAILDRTPWRAEEPVV 246

Query: 241 IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL 300
           IVAPMFHAWGFSQL  AAS+ACTI+TRRKFDPEATL+L+DRHRATGL VVPVMFDRIMEL
Sbjct: 247 IVAPMFHAWGFSQLAFAASMACTIITRRKFDPEATLELVDRHRATGLCVVPVMFDRIMEL 306

Query: 301 PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR 360
           P  VLNRY GR+LRFAAASGSRMRPDVV+AFM+RFGDVIYNNYNATEAGMIATATPADLR
Sbjct: 307 PEDVLNRYDGRSLRFAAASGSRMRPDVVIAFMDRFGDVIYNNYNATEAGMIATATPADLR 366

Query: 361 AAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSG 420
           AAPDTAGRPAEGTEIRILD +  ++P GEVG+I+V N +QFDGYTSGTTKDFH GFM SG
Sbjct: 367 AAPDTAGRPAEGTEIRILDGDLRDLPTGEVGTIYVRNSTQFDGYTSGTTKDFHEGFMCSG 426

Query: 421 DVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRL 480
           DVG LD  GRLFVVGRDDEMIVSGGENVYPIEVEK L THP VAEAAVIGVDDEQ+GQRL
Sbjct: 427 DVGRLDDAGRLFVVGRDDEMIVSGGENVYPIEVEKVLTTHPAVAEAAVIGVDDEQFGQRL 486

Query: 481 AAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAK 540
           AAFVVL  DA +D+      LK HVRDNLANYKVPR+I +LDELPR STGKI R ELQ K
Sbjct: 487 AAFVVLSGDATVDD------LKSHVRDNLANYKVPRDITILDELPRNSTGKIARRELQEK 540

Query: 541 VCG 543
           V G
Sbjct: 541 VNG 543


>tr|A1T1N1|A1T1N1_MYCVP Tax_Id=350058 SubName: Full=AMP-dependent
           synthetase and ligase;[Mycobacterium vanbaalenii]
          Length = 544

 Score =  762 bits (1968), Expect = 0.0
 Identities = 384/541 (70%), Positives = 441/541 (81%), Gaps = 10/541 (1%)

Query: 5   IDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDEL 64
           + + LGL++T+ R+G+IAPMRPD+YL+IA AM+RE M          QRCPDR GL+DEL
Sbjct: 7   VTKTLGLLSTMVRAGVIAPMRPDKYLRIAGAMQRENMAITSGFAAAAQRCPDRAGLIDEL 66

Query: 65  GTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTA 124
           G LTWRQ+D+R++           G P+V+ +M RNHRGFV+AL+AANRIGAD+LLLNT+
Sbjct: 67  GILTWRQIDQRADAFAAALQALPGGQPEVIALMARNHRGFVDALIAANRIGADVLLLNTS 126

Query: 125 FAGPALADVVAREGVD---TVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHD-LTVEQL 180
           FAGPALA+V+ REG      V+YDEEFT TVDRA  GRP  TRIVAW+D   D LTVE +
Sbjct: 127 FAGPALAEVMEREGEGRSVAVVYDEEFTDTVDRALAGRPDTTRIVAWTDTPGDRLTVEGM 186

Query: 181 VNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIV 240
           +  H G +P R     R+ILLTSGTTGTPKGA H         LKAILDRTPWRAEQP+V
Sbjct: 187 IAEHGGQEPVRAPEKSRVILLTSGTTGTPKGASHSGGDPS--VLKAILDRTPWRAEQPVV 244

Query: 241 IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL 300
           IVAPMFHAWGFSQL  AAS++CTIVTRR+FDPEATL+L+D++RATGL VVPVMFDRIM+L
Sbjct: 245 IVAPMFHAWGFSQLAFAASMSCTIVTRRRFDPEATLELVDKYRATGLCVVPVMFDRIMDL 304

Query: 301 PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR 360
           P +VL++YSGR+LRFAAASGSRMRPDVV+ FM+RFGDVIYNNYNATEAGMIATATP DLR
Sbjct: 305 PDEVLDKYSGRSLRFAAASGSRMRPDVVIKFMDRFGDVIYNNYNATEAGMIATATPRDLR 364

Query: 361 AAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSG 420
           AAPDTAGRPAEGTEIRILD +FNEVP GEVG I+V N +QFDGYT+G TKDFH GFMSSG
Sbjct: 365 AAPDTAGRPAEGTEIRILDADFNEVPTGEVGGIYVRNSTQFDGYTTGKTKDFHEGFMSSG 424

Query: 421 DVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRL 480
           DVGY D  GRLFVVGRDDEMIVSGGENVYPIEVEKTLA HP+VAEA V+GVDDE++GQRL
Sbjct: 425 DVGYFDEAGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPDVAEATVLGVDDEKFGQRL 484

Query: 481 AAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAK 540
            AFVVL  DA     A PETLKQHVRDNLANYKVPREI +LDELPRG TGKI R +LQ +
Sbjct: 485 EAFVVLTADA----AATPETLKQHVRDNLANYKVPREITILDELPRGVTGKISRKDLQDR 540

Query: 541 V 541
           +
Sbjct: 541 L 541


>tr|A4T3U7|A4T3U7_MYCGI Tax_Id=350054 SubName: Full=AMP-dependent
           synthetase and ligase;[Mycobacterium gilvum]
          Length = 544

 Score =  760 bits (1962), Expect = 0.0
 Identities = 383/541 (70%), Positives = 441/541 (81%), Gaps = 10/541 (1%)

Query: 5   IDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDEL 64
           +   LGLI+T+ R+G+IAPMRPD+Y++I  AM+RE M          QRCPDR GLVDEL
Sbjct: 7   VTNALGLISTMMRAGVIAPMRPDKYMRIVGAMQRENMAITSGFAAAAQRCPDRAGLVDEL 66

Query: 65  GTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTA 124
           G LTWRQ+D+R++           G P+V+G+M RNHRGFV++L+AANRIGAD+LLLNT+
Sbjct: 67  GILTWRQIDQRADALAAALQALPEGQPEVIGLMARNHRGFVDSLIAANRIGADVLLLNTS 126

Query: 125 FAGPALADVVAREGVD---TVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHD-LTVEQL 180
           FAGPALA+V+ REG      VIYDEEFT TVDRA   RP+ TRI+AW+D   D LTVE L
Sbjct: 127 FAGPALAEVLQREGEGRAVAVIYDEEFTETVDRAVADRPETTRILAWTDSDTDALTVEGL 186

Query: 181 VNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIV 240
           +  H G +P R+    R+ILLTSGTTGTPKGAKH         LK+ILDRTPWRAEQP+V
Sbjct: 187 IAEHGGQEPVRSVEKARVILLTSGTTGTPKGAKHSGGDPG--VLKSILDRTPWRAEQPVV 244

Query: 241 IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL 300
           IVAPMFHAWGFSQL  AAS++CTI+TRRKFDPEATL+L+D+ RATGL VVPVMFDRIMEL
Sbjct: 245 IVAPMFHAWGFSQLAFAASMSCTIITRRKFDPEATLELVDKFRATGLCVVPVMFDRIMEL 304

Query: 301 PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR 360
           P +VL++YSGR+LRFAAASGSRMRPD+V+ FM+RFGDVIYNNYNATEAGMIATATP DLR
Sbjct: 305 PEEVLDKYSGRSLRFAAASGSRMRPDIVIKFMDRFGDVIYNNYNATEAGMIATATPRDLR 364

Query: 361 AAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSG 420
           AAPDTAGRPAEGTEI+ILD EFNEVP GE G I+V N +QFDGYTSG+TKDFH GFMSSG
Sbjct: 365 AAPDTAGRPAEGTEIKILDSEFNEVPTGETGGIWVRNSTQFDGYTSGSTKDFHDGFMSSG 424

Query: 421 DVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRL 480
           DVGYLD  GRLFVVGRDDEMIVSGGENVYPIEVEKTL +HP+VAEA V+GVDDE++GQRL
Sbjct: 425 DVGYLDEEGRLFVVGRDDEMIVSGGENVYPIEVEKTLTSHPDVAEATVLGVDDEKFGQRL 484

Query: 481 AAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAK 540
           AAFVVL P A     A PE LKQHVRDNLANYKVPREI VLDELPR  TGKI R +L+ +
Sbjct: 485 AAFVVLNPGA----AATPEALKQHVRDNLANYKVPREITVLDELPRSITGKISRKDLKDR 540

Query: 541 V 541
           +
Sbjct: 541 L 541


>tr|A3Q422|A3Q422_MYCSJ Tax_Id=164757 SubName: Full=AMP-dependent
           synthetase and ligase;[Mycobacterium sp.]
          Length = 540

 Score =  746 bits (1927), Expect = 0.0
 Identities = 382/543 (70%), Positives = 435/543 (80%), Gaps = 8/543 (1%)

Query: 1   MAPRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGL 60
           M  R+ +  G++ T+ R+ +IAP+RPDRYL++ AA+RR GM          QRCPDRPGL
Sbjct: 1   MMNRLRKTAGIVGTMYRARVIAPLRPDRYLRMGAAVRRAGMSVTTGFALAAQRCPDRPGL 60

Query: 61  VDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILL 120
           +DELGTLTWR+LD  S+           G P+VVGIM RNHRGFVEALVAANRIGAD+LL
Sbjct: 61  IDELGTLTWRELDSHSDALAAALQTLPGGQPEVVGIMARNHRGFVEALVAANRIGADVLL 120

Query: 121 LNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQ--HDLTVE 178
           LNT+FAGPALADVVARE VD VIYDEEF  +V +A   RP+A +IVAW+D      +TV 
Sbjct: 121 LNTSFAGPALADVVAREQVDAVIYDEEFAPSVAQALKDRPKAAKIVAWTDDPDAQAVTVA 180

Query: 179 QLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQP 238
            L++ H+G +P  + RT +LILLTSGTTG+PKGA+H         LK+ILDRTPWRAE+ 
Sbjct: 181 GLIDGHIGQRPLPSDRTSKLILLTSGTTGSPKGARHSGGGAD--ALKSILDRTPWRAEEV 238

Query: 239 IVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIM 298
            VIVAPMFHAWGF QLV AA +ACTIVTRRKFDPEATL L+D HRATGL +VPVMFDRI+
Sbjct: 239 TVIVAPMFHAWGFGQLVFAAMMACTIVTRRKFDPEATLALVDEHRATGLCLVPVMFDRIV 298

Query: 299 ELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPAD 358
           +LP  VL+RYSGRTLRFAAASGSRMRPDVV+ FM+RFGDVIYNNYNATEAGMIATATP D
Sbjct: 299 DLPEDVLSRYSGRTLRFAAASGSRMRPDVVIKFMDRFGDVIYNNYNATEAGMIATATPED 358

Query: 359 LRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMS 418
           LRAAPDTAG+ AEGT+IRILD +F+E P GEVG+I+V N SQFDGYTSG  K+FH G+MS
Sbjct: 359 LRAAPDTAGKAAEGTDIRILDSDFHEQPRGEVGTIYVRNSSQFDGYTSGANKNFHDGYMS 418

Query: 419 SGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQ 478
           SGDVGYLD  GRLFVVGRDDEMIVSGGENVYPIEVEK LATHPEV EAAVIGVDDEQYGQ
Sbjct: 419 SGDVGYLDEAGRLFVVGRDDEMIVSGGENVYPIEVEKALATHPEVNEAAVIGVDDEQYGQ 478

Query: 479 RLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           RLAAFVVL   A    +A PE LK HVR+NLANYKVPR I VL ELPRGSTGKI+R EL 
Sbjct: 479 RLAAFVVLRDGA----SATPEDLKAHVRENLANYKVPRSITVLGELPRGSTGKIVRRELH 534

Query: 539 AKV 541
           A +
Sbjct: 535 ALI 537


>tr|Q1B5H0|Q1B5H0_MYCSS Tax_Id=164756 SubName: Full=AMP-dependent
           synthetase and ligase;[Mycobacterium sp.]
          Length = 548

 Score =  738 bits (1906), Expect = 0.0
 Identities = 374/541 (69%), Positives = 429/541 (79%), Gaps = 7/541 (1%)

Query: 2   APRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLV 61
           A ++   +GL+ TL RS LIAPMRPDRYLK+ AA+RR GM          QRCPDRPGL+
Sbjct: 9   AAKVGASVGLMQTLWRSRLIAPMRPDRYLKMGAAVRRVGMTATVGFATAAQRCPDRPGLI 68

Query: 62  DELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLL 121
           DE G LT+ +LD+ S+           G+P  V IMCRNHRGF+EAL+AANRIGA+ LLL
Sbjct: 69  DERGMLTFAELDDASDALAVALQGLPGGTPGTVAIMCRNHRGFIEALLAANRIGANALLL 128

Query: 122 NTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSD---GQHDLTVE 178
           NT+FAGPALA+V  REG D VIYDEEF+ TV+RA  G P A RI+AW+D   G  + TV+
Sbjct: 129 NTSFAGPALAEVAEREGADVVIYDEEFSETVERALSGLPDAVRIIAWTDEPGGGAETTVD 188

Query: 179 QLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQP 238
            L+ AH G++P    R+  +ILLTSGTTGTPKGAK          LKA+LDRTPWRAE+ 
Sbjct: 189 ALIEAHRGERPRPAERSSEIILLTSGTTGTPKGAKRSAGSGGAGDLKAVLDRTPWRAEET 248

Query: 239 IVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIM 298
            VIVAPMFHAWGFSQL+ A  LACTIVTRR+FDPEATL L+D H+ATGL+VVPVMFDRIM
Sbjct: 249 TVIVAPMFHAWGFSQLLFAGLLACTIVTRRRFDPEATLALVDEHKATGLIVVPVMFDRIM 308

Query: 299 ELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPAD 358
           +LP +V  RYSGR+LRFAAASGSRMRPDVV AFM++FGDVIYNNYNATEAGMIATATPAD
Sbjct: 309 DLPDEVRARYSGRSLRFAAASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPAD 368

Query: 359 LRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMS 418
           LRAAPDTAG PA+GTEIRI D +F E+P GE GSIFV + + FDGYTSG+TKDFH GFM+
Sbjct: 369 LRAAPDTAGTPADGTEIRIFDPDFRELPPGETGSIFVRSGTLFDGYTSGSTKDFHDGFMA 428

Query: 419 SGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQ 478
           SGDVGYLD NGRLFVVGRDDEMIVSGGENVYPIEVEKTLA HP VAEA V+GVDDE+YGQ
Sbjct: 429 SGDVGYLDENGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPGVAEAEVLGVDDEKYGQ 488

Query: 479 RLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           RLAAFVV    A L     P+ LK+HVRDNLANYKVPR+I +LDELPRG TGK+LR EL+
Sbjct: 489 RLAAFVVPAAGASL----TPDELKEHVRDNLANYKVPRDIVILDELPRGGTGKVLRNELR 544

Query: 539 A 539
           A
Sbjct: 545 A 545


>tr|A1UJL6|A1UJL6_MYCSK Tax_Id=189918 SubName: Full=AMP-dependent
           synthetase and ligase;[Mycobacterium sp.]
          Length = 548

 Score =  738 bits (1906), Expect = 0.0
 Identities = 374/541 (69%), Positives = 429/541 (79%), Gaps = 7/541 (1%)

Query: 2   APRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLV 61
           A ++   +GL+ TL RS LIAPMRPDRYLK+ AA+RR GM          QRCPDRPGL+
Sbjct: 9   AAKVGASVGLMQTLWRSRLIAPMRPDRYLKMGAAVRRVGMTATVGFATAAQRCPDRPGLI 68

Query: 62  DELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLL 121
           DE G LT+ +LD+ S+           G+P  V IMCRNHRGF+EAL+AANRIGA+ LLL
Sbjct: 69  DERGMLTFAELDDASDALAVALQGLPGGTPGTVAIMCRNHRGFIEALLAANRIGANALLL 128

Query: 122 NTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSD---GQHDLTVE 178
           NT+FAGPALA+V  REG D VIYDEEF+ TV+RA  G P A RI+AW+D   G  + TV+
Sbjct: 129 NTSFAGPALAEVAEREGADVVIYDEEFSETVERALSGLPDAVRIIAWTDEPGGGAETTVD 188

Query: 179 QLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQP 238
            L+ AH G++P    R+  +ILLTSGTTGTPKGAK          LKA+LDRTPWRAE+ 
Sbjct: 189 ALIEAHRGERPRPAERSSEIILLTSGTTGTPKGAKRSAGSGGAGDLKAVLDRTPWRAEET 248

Query: 239 IVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIM 298
            VIVAPMFHAWGFSQL+ A  LACTIVTRR+FDPEATL L+D H+ATGL+VVPVMFDRIM
Sbjct: 249 TVIVAPMFHAWGFSQLLFAGLLACTIVTRRRFDPEATLALVDEHKATGLIVVPVMFDRIM 308

Query: 299 ELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPAD 358
           +LP +V  RYSGR+LRFAAASGSRMRPDVV AFM++FGDVIYNNYNATEAGMIATATPAD
Sbjct: 309 DLPDEVRARYSGRSLRFAAASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPAD 368

Query: 359 LRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMS 418
           LRAAPDTAG PA+GTEIRI D +F E+P GE GSIFV + + FDGYTSG+TKDFH GFM+
Sbjct: 369 LRAAPDTAGTPADGTEIRIFDPDFRELPPGETGSIFVRSGTLFDGYTSGSTKDFHDGFMA 428

Query: 419 SGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQ 478
           SGDVGYLD NGRLFVVGRDDEMIVSGGENVYPIEVEKTLA HP VAEA V+GVDDE+YGQ
Sbjct: 429 SGDVGYLDENGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPGVAEAEVLGVDDEKYGQ 488

Query: 479 RLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           RLAAFVV    A L     P+ LK+HVRDNLANYKVPR+I +LDELPRG TGK+LR EL+
Sbjct: 489 RLAAFVVPAAGASL----TPDELKEHVRDNLANYKVPRDIVILDELPRGGTGKVLRNELR 544

Query: 539 A 539
           A
Sbjct: 545 A 545


>tr|A3Q319|A3Q319_MYCSJ Tax_Id=164757 SubName: Full=AMP-dependent
           synthetase and ligase;[Mycobacterium sp.]
          Length = 548

 Score =  738 bits (1904), Expect = 0.0
 Identities = 374/541 (69%), Positives = 429/541 (79%), Gaps = 7/541 (1%)

Query: 2   APRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLV 61
           A ++   +GL+ TL RS LIAPMRPDRYLK+ AA+RR GM          QRCPDRPGL+
Sbjct: 9   AAKVGASVGLMQTLWRSRLIAPMRPDRYLKMGAAVRRVGMTATVGFATAAQRCPDRPGLI 68

Query: 62  DELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLL 121
           DE G LT+ +LD+ S+           G+P  V IMCRNHRGF+EAL+AANRIGA+ LLL
Sbjct: 69  DERGMLTFAELDDASDALAVALQGLPGGTPGTVAIMCRNHRGFIEALLAANRIGANALLL 128

Query: 122 NTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSD---GQHDLTVE 178
           NT+FAGPALA+V  REG D VIYDEEF+ TV+RA  G P A RI+AW+D   G  + TV+
Sbjct: 129 NTSFAGPALAEVAEREGADVVIYDEEFSETVERALSGLPDAVRIIAWTDEPGGGAETTVD 188

Query: 179 QLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQP 238
            L+ AH G++P    R+  +ILLTSGTTGTPKGAK          LKA+LDRTPWRAE+ 
Sbjct: 189 ALIEAHRGERPRPAERSSEIILLTSGTTGTPKGAKRSAGSGGAGDLKAVLDRTPWRAEET 248

Query: 239 IVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIM 298
            VIVAPMFHAWGFSQL+ A  LACTIVTRR+FDPEATL L+D H+ATGL+VVPVMFDRIM
Sbjct: 249 TVIVAPMFHAWGFSQLLFAGLLACTIVTRRRFDPEATLALVDEHKATGLIVVPVMFDRIM 308

Query: 299 ELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPAD 358
           +LP +V  RYSGR+LRFAAASGSRMRPDVV AFM++FGDVIYNNYNATEAGMIATATPAD
Sbjct: 309 DLPDEVRARYSGRSLRFAAASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPAD 368

Query: 359 LRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMS 418
           LRAAPDTAG PA+GTEIRI D +F E+P GE GSIFV + + FDGYTSG+TKDFH GFM+
Sbjct: 369 LRAAPDTAGTPADGTEIRIFDPDFRELPPGETGSIFVRSGTLFDGYTSGSTKDFHDGFMA 428

Query: 419 SGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQ 478
           SGDVGYLD NGRLFVVGRDDEMIVSGGENVYPIEVEKTLA HP VAEA V+GVDDE+YGQ
Sbjct: 429 SGDVGYLDENGRLFVVGRDDEMIVSGGENVYPIEVEKTLAAHPGVAEAEVLGVDDEKYGQ 488

Query: 479 RLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           RLAAFVV    A L     P+ LK+HVRDNLANYKVPR+I +LDELPRG TGK+LR EL+
Sbjct: 489 RLAAFVVPAAGAAL----TPDELKEHVRDNLANYKVPRDIVILDELPRGGTGKVLRNELR 544

Query: 539 A 539
           A
Sbjct: 545 A 545


>tr|A1TCV2|A1TCV2_MYCVP Tax_Id=350058 SubName: Full=AMP-dependent
           synthetase and ligase;[Mycobacterium vanbaalenii]
          Length = 530

 Score =  734 bits (1895), Expect = 0.0
 Identities = 376/533 (70%), Positives = 424/533 (79%), Gaps = 8/533 (1%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           LGL+ TL R+ LIAPMRPDRYL++  AMRR G+          QRCPD PG++DELGTLT
Sbjct: 5   LGLLATLWRARLIAPMRPDRYLRMGLAMRRAGLTATVGFAAAAQRCPDLPGIIDELGTLT 64

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           W+QLD+R +            +P+ V +MCRNHRGFVEALV ANRIGAD+LLLNT+FAGP
Sbjct: 65  WKQLDDRCDALAAALQKH---TPRTVAVMCRNHRGFVEALVGANRIGADVLLLNTSFAGP 121

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQH-DLTVEQLVNAHLGD 187
           A+A+V+ REG D VIYD+EFTATVDRA    P  TRI+AW+D      T+E L++AHLG 
Sbjct: 122 AMAEVIEREGADIVIYDQEFTATVDRALRDVPGTTRILAWTDADDGSTTLEALIDAHLGQ 181

Query: 188 QPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMFH 247
           +PE   R   +ILLTSGTTGTPKGAK          LKA+LDRTPWRA +PIVI APMFH
Sbjct: 182 RPEPATRKSDIILLTSGTTGTPKGAKRSAGSGGASDLKAVLDRTPWRAGEPIVIAAPMFH 241

Query: 248 AWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLNR 307
           AWGFSQL+ AA LAC IVTRRKFDPEATL LIDRHRATGL VVPVMFDRIMELP +V NR
Sbjct: 242 AWGFSQLLFAALLACPIVTRRKFDPEATLALIDRHRATGLAVVPVMFDRIMELPAEVRNR 301

Query: 308 YSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTAG 367
           YSGR+LRFA ASGSRMRPDVV AFM++FGDVIYNNYNATEAGMIATATPADLRAAPDTAG
Sbjct: 302 YSGRSLRFATASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPADLRAAPDTAG 361

Query: 368 RPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLDR 427
           R A+GTE+RILD E  +VP GEVG IFV + + FDGYTSGTTK FH GFM+SGD+GYLD 
Sbjct: 362 RAADGTELRILDAEHRDVPTGEVGQIFVRSSTLFDGYTSGTTKAFHDGFMASGDMGYLDG 421

Query: 428 NGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVLE 487
            GRLFVVGRDDEMIVSGGENVYPIEVEKTL TH  VAEAAV+GVDDEQYGQRLAAFVV  
Sbjct: 422 AGRLFVVGRDDEMIVSGGENVYPIEVEKTLTTHAAVAEAAVLGVDDEQYGQRLAAFVVPA 481

Query: 488 PDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAK 540
             A    +   E LKQHVR+NLANYKVPR+I ++ ELPRGSTGKILR EL+ +
Sbjct: 482 AGA----SVTVEELKQHVRENLANYKVPRDITIMAELPRGSTGKILRNELRGR 530


>tr|A0QHZ3|A0QHZ3_MYCA1 Tax_Id=243243 SubName: Full=Acyl-CoA
           synthase;[Mycobacterium avium]
          Length = 447

 Score =  725 bits (1871), Expect = 0.0
 Identities = 364/451 (80%), Positives = 401/451 (88%), Gaps = 4/451 (0%)

Query: 93  VVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGPALADVVAREGVDTVIYDEEFTATV 152
           ++GIMCRNHRGFVEA VAA+RIGADI+LLNT+FAGPALADV+ REGVD VIYDEEFTATV
Sbjct: 1   MIGIMCRNHRGFVEAPVAADRIGADIVLLNTSFAGPALADVITREGVDAVIYDEEFTATV 60

Query: 153 DRAFDGRPQATRIVAWSDGQHDLTVEQLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGA 212
           DRA  GRP A RIVAW+D +H  TV++L+ +  G QP RTGR G++ILLTSGTTGTPKGA
Sbjct: 61  DRALAGRPDAIRIVAWTDTEHQHTVDKLIASKAGAQPIRTGRKGKMILLTSGTTGTPKGA 120

Query: 213 KHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDP 272
           K         TLKAILDRTPWRAE+P+VIVAPMFHAWGFSQL+LAAS AC ++TRRKFDP
Sbjct: 121 KQSGGNAGIGTLKAILDRTPWRAEEPVVIVAPMFHAWGFSQLLLAASFACPVITRRKFDP 180

Query: 273 EATLDLIDRHRATGLVVVPVMFDRIMELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFM 332
           EATLDLIDRHRATGLVVVPVMFDRIM+LP +V  RY  R+LRFAAASGSRMRPDVVVAFM
Sbjct: 181 EATLDLIDRHRATGLVVVPVMFDRIMDLPAEVRRRYECRSLRFAAASGSRMRPDVVVAFM 240

Query: 333 NRFGDVIYNNYNATEAGMIATATPADLRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGS 392
           + FGDVIYNNYNATEAGMIATATPADLRAAPDTAGRPA GTEIRILD EFNE+P GEVG+
Sbjct: 241 DEFGDVIYNNYNATEAGMIATATPADLRAAPDTAGRPAGGTEIRILDPEFNELPAGEVGT 300

Query: 393 IFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIE 452
           I+V N++QFDGYTSG++KDFH GFMSSGD+GYLD  GRLFVVGRDDEMIVSGGENVYPIE
Sbjct: 301 IYVRNNTQFDGYTSGSSKDFHEGFMSSGDLGYLDSAGRLFVVGRDDEMIVSGGENVYPIE 360

Query: 453 VEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANY 512
           VEKTLATHP+VAEAAVIGVDDEQYGQRLAAFVVL P+A     A PE LKQHVRDNLANY
Sbjct: 361 VEKTLATHPDVAEAAVIGVDDEQYGQRLAAFVVLAPEA----RATPEALKQHVRDNLANY 416

Query: 513 KVPREIAVLDELPRGSTGKILRAELQAKVCG 543
           KVPREI+VLDELPR STGKILRA+L+A+V G
Sbjct: 417 KVPREISVLDELPRSSTGKILRADLRARVGG 447


>tr|A4T888|A4T888_MYCGI Tax_Id=350054 SubName: Full=AMP-dependent
           synthetase and ligase;[Mycobacterium gilvum]
          Length = 535

 Score =  724 bits (1869), Expect = 0.0
 Identities = 374/541 (69%), Positives = 425/541 (78%), Gaps = 11/541 (2%)

Query: 1   MAPRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGL 60
           M+   DQ  GL+ TL R+ LIAPMRPDRYL++  AMRR G+          QRCPDRPG+
Sbjct: 1   MSSAADQF-GLLATLWRARLIAPMRPDRYLRMGLAMRRAGLTATVGFAAAAQRCPDRPGI 59

Query: 61  VDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILL 120
           +DELGTLTW+QLD+R +             PK V +MCRNHRGFVEALVAANRIGAD+LL
Sbjct: 60  IDELGTLTWKQLDDRCDALGVALQKE---KPKTVAVMCRNHRGFVEALVAANRIGADVLL 116

Query: 121 LNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDL---TV 177
           LNT+FAGPA+A+VV REG D VIYD+EFT TVDRA      A RIVAW D        TV
Sbjct: 117 LNTSFAGPAMAEVVEREGADIVIYDQEFTETVDRALADTCGARRIVAWVDDPAQAGTATV 176

Query: 178 EQLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQ 237
           E L++AHLG +P+   R   +ILLTSGTTG+PKGAK          LKA+LDRTPWRAE+
Sbjct: 177 EALIDAHLGQRPQPATRKSDVILLTSGTTGSPKGAKRSAGSGGSGDLKAVLDRTPWRAEE 236

Query: 238 PIVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRI 297
           PIVI APMFHAWGFSQL+ AA LAC IVTRRKFDP ATL L+D++RATGL VVPVMFDRI
Sbjct: 237 PIVIAAPMFHAWGFSQLLFAALLACPIVTRRKFDPAATLALVDKYRATGLAVVPVMFDRI 296

Query: 298 MELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPA 357
           M+LP +V NRYSGR+LRFA ASGSRMRPDVV AFM++FGDVIYNNYNATEAGMIATATP 
Sbjct: 297 MDLPDEVRNRYSGRSLRFATASGSRMRPDVVTAFMDQFGDVIYNNYNATEAGMIATATPE 356

Query: 358 DLRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFM 417
           DLRAAPDTAG+ A+GTE+RILD E  E+P GEVG IFV + + FDGYTSG+TKDFH GFM
Sbjct: 357 DLRAAPDTAGKAADGTELRILDAEHRELPTGEVGQIFVRSGTLFDGYTSGSTKDFHDGFM 416

Query: 418 SSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYG 477
           +SGD+GYLD  GRLFVVGRDDEMIVSGGENVYPIEVEKTL +HPEVAEA V+GV+D +YG
Sbjct: 417 ASGDLGYLDDAGRLFVVGRDDEMIVSGGENVYPIEVEKTLMSHPEVAEATVLGVEDSEYG 476

Query: 478 QRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAEL 537
           QRLAAFVVL   + L     PE LKQHVR NLANYKVPR+I +L ELPRGSTGKILR EL
Sbjct: 477 QRLAAFVVLTDGSGL----TPEDLKQHVRANLANYKVPRDITILPELPRGSTGKILRNEL 532

Query: 538 Q 538
           +
Sbjct: 533 R 533


>tr|D0L3A2|D0L3A2_GORB4 Tax_Id=526226 SubName: Full=AMP-dependent
           synthetase and ligase;[Gordonia bronchialis]
          Length = 550

 Score =  534 bits (1376), Expect = e-149
 Identities = 280/529 (52%), Positives = 354/529 (66%), Gaps = 7/529 (1%)

Query: 11  LITTLARSGLIAPMRPDRYLKIAAAMRREG-MXXXXXXXXXXQRCPDRPGLVDELGTLTW 69
           LI TL  SG +  +R DRY+++  AMRR G             R P    L+D+ G LTW
Sbjct: 14  LIRTLVGSGFLGSLRLDRYVRMGLAMRRHGGASPVSGIGLAAARDPHGRALLDDAGHLTW 73

Query: 70  RQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGPA 129
           R+LD+R +                V IMCRNHRG +E+L A +R+G D +LLNT FA P 
Sbjct: 74  RELDDRCDALAAALADLGGHRVTTVAIMCRNHRGIIESLAATSRLGLDSVLLNTGFAAPQ 133

Query: 130 LADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDL-TVEQLVNAHLGDQ 188
           LADV+ RE VD VI D+EF   +  A    PQ   + AW +G     TV+ L+ A+LG +
Sbjct: 134 LADVLIREHVDLVIADDEFDGLIAHALGRNPQLRHVRAWVEGTATGDTVDGLIEANLGRR 193

Query: 189 PERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMFHA 248
                R GR++LLTSGTTGTPKGA+         +L A+LDR PWRA +  VI AP+FHA
Sbjct: 194 APVPERAGRIVLLTSGTTGTPKGARRGGSTDIG-SLAAMLDRIPWRAGETTVIAAPIFHA 252

Query: 249 WGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLNRY 308
           WGF Q+ ++A++ CT+V RR+FDP ATL+L+  H A GL VVPVM +RIM+LP  VL+ +
Sbjct: 253 WGFGQVAISATMTCTMVMRRRFDPVATLELVREHGAGGLAVVPVMLERIMDLPDDVLDAH 312

Query: 309 SGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTAGR 368
              +LRF  ASGSRMR D ++ FM+RFGDV+YN+YNATEAG+I+TATPADLR APDTAGR
Sbjct: 313 QMPSLRFVTASGSRMRTDALLGFMDRFGDVVYNSYNATEAGLISTATPADLRLAPDTAGR 372

Query: 369 PAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLDRN 428
           P  GT +R+LD    EVP GEVG I V ++S FDGYTS  TK F  G M SGDVG +D  
Sbjct: 373 PLTGTSVRLLDDADREVPTGEVGRIVVASNSGFDGYTSSDTKAFADGHMVSGDVGRVDER 432

Query: 429 GRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVLEP 488
           G LFVVGRDDEMIVSGGENVYP+EVE+ +  HP V E AVIGVDD ++GQRLAA+VV  P
Sbjct: 433 GLLFVVGRDDEMIVSGGENVYPLEVEQVIGAHPAVREVAVIGVDDPKFGQRLAAYVVRAP 492

Query: 489 DADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAEL 537
              +      E L+ HVR+ LA +KVPR++  +DELPR +TGK+L+ +L
Sbjct: 493 QTIV----GAEALRDHVREQLAGFKVPRDVHFIDELPRNATGKVLKRQL 537


>tr|A1SI70|A1SI70_NOCSJ Tax_Id=196162 SubName: Full=AMP-dependent
           synthetase and ligase;[Nocardioides sp.]
          Length = 541

 Score =  432 bits (1110), Expect = e-119
 Identities = 244/532 (45%), Positives = 313/532 (58%), Gaps = 19/532 (3%)

Query: 12  ITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLTWRQ 71
           +  L  +G+I P  P    K+A A++  G              P R  ++DELG+LT+ +
Sbjct: 20  LKVLGEAGVIRPRNPVALAKVAKALKDWGTGPAGGFTAAALLDPRRTAIIDELGSLTFAE 79

Query: 72  LDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGPALA 131
           L  RSN                V +MCRNHRGFVEA +AA ++GADIL LNTAFAGP L 
Sbjct: 80  LQRRSNALARAFAELGVSEGDSVALMCRNHRGFVEASIAAAKLGADILYLNTAFAGPQLV 139

Query: 132 DVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAW-----SDGQHDLTVEQLVNAHLG 186
           +V+ RE    V++DEEFT  + +A  G    T ++AW     SD   D T+E L+    G
Sbjct: 140 EVLEREQPALVVHDEEFTRLLAKADVG----TSVLAWTDSADSDDSADPTLESLIAGRSG 195

Query: 187 DQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMF 246
              E TGR GR+++LTSGTTGTPKGA             ++L R P R      I AP+F
Sbjct: 196 ADLEPTGRHGRIVILTSGTTGTPKGAPRSEAGIDAAV--SLLSRMPLRYGWRTHIAAPLF 253

Query: 247 HAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLN 306
           H WGF+ L LA  L  TIV RR+FDPEA L      R   LVV+PVM  R+M LP + L 
Sbjct: 254 HTWGFAHLALAMLLGSTIVLRRRFDPEACLRATQDERCDSLVVIPVMLQRMMALPEETLA 313

Query: 307 RYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTA 366
           RY    ++  A+SGS +  D+   +M+ FGD +YN Y +TE    + ATP DLR AP  A
Sbjct: 314 RYDLSRVQVVASSGSALPGDLATDWMDHFGDHLYNIYGSTEVAYASIATPLDLREAPSAA 373

Query: 367 GRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLD 426
           G+P   T ++ILD +  E+P+GE G IFV N   F+GYT G  K+   G MS+GDVG  D
Sbjct: 374 GKPPYATIVKILDPDGRELPQGETGRIFVGNGLLFEGYTGGGHKEVVDGLMSTGDVGRFD 433

Query: 427 RNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVL 486
            +GRL V GRDDEMIVSGGENV+P EVE  L  H  V E A +GVDD  +G+RL AFVV+
Sbjct: 434 TDGRLHVEGRDDEMIVSGGENVFPKEVEDCLMRHDAVVEVAAVGVDDPDFGKRLRAFVVV 493

Query: 487 EPDADLDENAAPE-TLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAEL 537
                    A PE  LK  V++NLA YKVPR++  LDELPR +TGK+L+ +L
Sbjct: 494 -------SRAVPEQELKDWVKENLARYKVPRDVVFLDELPRNATGKVLKRDL 538


>tr|A4F991|A4F991_SACEN Tax_Id=405948 (fadD12)SubName: Full=Acyl-CoA
           synthase; EC=6.2.1.-;[Saccharopolyspora erythraea]
          Length = 551

 Score =  415 bits (1066), Expect = e-114
 Identities = 228/542 (42%), Positives = 320/542 (59%), Gaps = 15/542 (2%)

Query: 2   APRIDQILGLITT--LARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPG 59
           A R ++  GL T   LAR G++ PMRPD+ L+I  A  R G+           R PDRP 
Sbjct: 11  AVRPERARGLQTAYILARQGVVRPMRPDKLLRILRAWLRWGITPPLAYAVGAIRHPDRPA 70

Query: 60  LVDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADIL 119
           ++DE G +++ ++  R+            G    VGI+CRNH G +E +VA  ++G D++
Sbjct: 71  VIDERGAISYAEVSLRTTRLANGLRERGIGESSRVGILCRNHHGAIETIVACGKLGTDVV 130

Query: 120 LLNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIV-AWSDGQ-HDLTV 177
           LLNT  +   LA V+A + VD ++ D E+    DR     P    +V AW++G     TV
Sbjct: 131 LLNTGLSSSQLAAVLAEQRVDLLVLDAEY----DRHLPELPADLDVVLAWTEGSTRHWTV 186

Query: 178 EQLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQ 237
           E L+         R  R  R+I+LTSGTTGTPKGA+             ++ R P R+ +
Sbjct: 187 EHLIATSQAKALPRRPRHARMIVLTSGTTGTPKGARRPDPPGIGPAA-TVMSRIPLRSGE 245

Query: 238 PIVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRI 297
            +++ AP+FH WG +   L A L  T+V  R+F+P   L +  R++ T +  VPVM  RI
Sbjct: 246 RMLVCAPVFHTWGLAAFQLGAVLGATLVLPRRFEPGHALSVAKRYQCTSMFAVPVMLQRI 305

Query: 298 MELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPA 357
           ++LP +   R    +LR  A+SGS M  D+   F   FG V+YN Y +TE   ++ ATP+
Sbjct: 306 LDLPAE--ERIRPESLRVVASSGSAMPADLATRFQRAFGPVLYNLYGSTEVSWVSIATPS 363

Query: 358 DLRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFM 417
           +LRAAP TAGRP  GT +RILD+       G  G IF  ND  F+GYTSG  K+   G M
Sbjct: 364 ELRAAPSTAGRPPRGTTVRILDENGKPARTGATGRIFAGNDMLFEGYTSGGRKEVVDGLM 423

Query: 418 SSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYG 477
           S+GD+G +D +GRLFVVGR+D+MI+SGGENVYP E E  +A  PEV E AV+GV+D ++G
Sbjct: 424 STGDLGRIDSSGRLFVVGREDDMIISGGENVYPKETEDAIAALPEVREVAVVGVEDAEFG 483

Query: 478 QRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAEL 537
           QRLAAFVVL+ D  LD     + L++ VR +L+ + +PR++  LDELPR +TGK++  EL
Sbjct: 484 QRLAAFVVLQDDTRLD----GDDLRERVRGSLSRFAMPRDVVFLDELPRNATGKVVPREL 539

Query: 538 QA 539
            A
Sbjct: 540 HA 541


>tr|C7MQ92|C7MQ92_SACVD Tax_Id=471857 SubName: Full=Acyl-CoA
           synthetase (AMP-forming)/AMP-acid ligase
           II;[Saccharomonospora viridis]
          Length = 539

 Score =  412 bits (1058), Expect = e-113
 Identities = 235/531 (44%), Positives = 314/531 (59%), Gaps = 15/531 (2%)

Query: 12  ITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLTWRQ 71
           +  L R+GL    R D  ++   + RR G           +R P   GLVDE G+LT+ Q
Sbjct: 20  LAVLYRAGLAPIPRLDEGIRSIISTRRYG-PLAGSVKIAARRDPHSVGLVDERGSLTYTQ 78

Query: 72  LDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGPALA 131
           LD RSN                V ++CR+HRG V AL+AA ++GA +LLLNT FA P L 
Sbjct: 79  LDLRSNALARAWAARGVRPGTTVAVLCRDHRGLVLALLAAGKLGAPVLLLNTGFAKPQLT 138

Query: 132 DVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNAHLG--DQP 189
           DV ARE V  +++DEEFT  +           R +AW+D      V  L +   G  D P
Sbjct: 139 DVAAREKVRVLVHDEEFTDLLGDIAG----VDRYLAWTDSTPPADVPTLDDIIAGSDDHP 194

Query: 190 -ERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMFHA 248
                + G L+LLTSGTTGTPKGA               LDR P R  +   + AP+FHA
Sbjct: 195 LPAPPKPGGLVLLTSGTTGTPKGAPRPKVSPFDSA--QFLDRIPLRVGEATFMGAPLFHA 252

Query: 249 WGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLNRY 308
            G SQ +L+ +L CT+V RRKFDPEATL  +  HR T LV+VP M  RI++L  +V+ RY
Sbjct: 253 TGISQFILSCALGCTVVVRRKFDPEATLRGVAEHRCTALVLVPTMLQRILDLGPEVIGRY 312

Query: 309 SGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTAGR 368
              +LR    +GS + P+V       FGDVI+N Y +TE  +   ATP D + AP T G+
Sbjct: 313 DTSSLRIIFVAGSALAPEVGNRATELFGDVIHNLYGSTEVAVATVATPEDWKRAPGTVGK 372

Query: 369 PAEGTEIRILDQEFNEVPEGEV-GSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLDR 427
           P  G  + + D+    +    V G +FV +   F+GYT G TK+   G +++GDVG+ D 
Sbjct: 373 PPVGCRVELYDEHGRRITRPYVTGRVFVGSGLAFEGYTDGRTKETINGLLATGDVGHFDA 432

Query: 428 NGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVLE 487
           +G LF+ GRDDEMIVSGGENVYP+EVE  L  HP+V EAAVIGV D+++GQRL AFVV++
Sbjct: 433 DGLLFIDGRDDEMIVSGGENVYPVEVENVLVEHPDVREAAVIGVPDDEFGQRLKAFVVVK 492

Query: 488 PDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
             A+LD +A    +++HVR+NLA YKVPR++  LD+LPR +TGK+LR  L+
Sbjct: 493 EGAELDADA----VREHVRNNLARYKVPRDVEFLDQLPRNATGKVLRNSLE 539


>tr|C1YR46|C1YR46_NOCDA Tax_Id=446468 SubName: Full=Acyl-CoA
           synthetase (AMP-forming)/AMP-acid ligase
           II;[Nocardiopsis dassonvillei subsp. dassonvillei DSM
           43111]
          Length = 546

 Score =  406 bits (1043), Expect = e-111
 Identities = 225/534 (42%), Positives = 298/534 (55%), Gaps = 13/534 (2%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           R   +L  +  L R+G+++P RPDR ++   A+R  G           +R PD   +VDE
Sbjct: 13  RTRHVLETVRVLVRAGVLSPGRPDRVVRQLRALRTWGATIAGGYAAANERVPDAVAVVDE 72

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
           LG  T+R++D R             G+   VG++CRNH GFV+ +VA  R+GAD +LLNT
Sbjct: 73  LGPTTFREMDLRGRELARDLRRAGVGAGARVGVLCRNHSGFVQTMVACGRLGADTVLLNT 132

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAW---SDGQHDLTVEQL 180
             +   LA  V   GV  V+ D EF           P   R+ AW   SDG     V   
Sbjct: 133 GLSAGQLAAAVGGNGVSVVVADAEFEGMCAEL---DPGVVRVTAWGEPSDGGPG--VPWR 187

Query: 181 VNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIV 240
                   PE   R GRL++LTSGTTG PKGA+            ++L R P R+   I+
Sbjct: 188 AREVSESDPEPPERPGRLVVLTSGTTGAPKGARRPTPRGPQDAA-SVLSRIPLRSSDRIL 246

Query: 241 IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL 300
           + AP+FH WG + + L  S+  T+V RR F+PE  L  +   R T L  VPVM  RIM+L
Sbjct: 247 VSAPIFHTWGLAGVQLGMSMRATLVMRRLFEPEDALRTVQEERCTALFAVPVMLRRIMDL 306

Query: 301 PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR 360
           P     RY   +LR  A SGS M P ++  FM+ FGDV+YN Y +TE      ATP ++R
Sbjct: 307 PRSTRERYDTSSLRIVACSGSAMSPQLITGFMDAFGDVLYNLYGSTEVSWATIATPGEMR 366

Query: 361 AAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSG 420
            +P TAGRP  GT I +LD    EVP G  GSI V ND  FDGYT G ++    G M +G
Sbjct: 367 LSPTTAGRPPLGTRIAVLDPGGVEVPPGTEGSIHVGNDMLFDGYTDGRSRRVADGLMETG 426

Query: 421 DVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRL 480
           D G++D NG L V GRDD+MIVSGGENV+P  VE+ + T PEV E  V GV DE++GQR 
Sbjct: 427 DRGHVDANGLLHVAGRDDDMIVSGGENVFPRPVEEAIVTLPEVREVVVTGVPDEEFGQRF 486

Query: 481 AAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILR 534
           AA+VV      +D    P  ++ HVR  L  + VPR++ V+DELPR +TGK+++
Sbjct: 487 AAYVVPHEGRGVD----PNQVRTHVRRVLGRFSVPRDVVVVDELPRNATGKVVK 536


>tr|Q5YYK7|Q5YYK7_NOCFA Tax_Id=37329 SubName: Full=Putative acyl-CoA
           synthetase;[Nocardia farcinica]
          Length = 556

 Score =  403 bits (1035), Expect = e-110
 Identities = 224/490 (45%), Positives = 295/490 (60%), Gaps = 18/490 (3%)

Query: 56  DRPGLVDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIG 115
           D P LVDE GTL++ +LD RS+           G   V+  +CR+HRGFV  ++AA ++G
Sbjct: 64  DAPALVDEHGTLSFTELDARSDALACGLAAAGLGPDTVLAALCRDHRGFVLTMLAAGKLG 123

Query: 116 ADILLLNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQAT-RIVAWSDGQHD 174
           A ++L+NT FA P LADV ARE V  +++D EF A V       P+ T R + W D  H+
Sbjct: 124 ARLVLMNTGFATPQLADVAAREKVGAILFDSEFAAVVSAV----PETTARFLTWVDEGHE 179

Query: 175 L-----TVEQLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILD 229
                 T++ LV+AH G+ P    R G +++LTSGTTGTPKGA               LD
Sbjct: 180 ADPAIRTIDALVDAHRGEAPAAPERPGGIVILTSGTTGTPKGAPRDKVSPLQSA--QFLD 237

Query: 230 RTPWRAEQPIVIVAPMFHAWGFSQLVLAASLACTIVTR-RKFDPEATLDLIDRHRATGLV 288
           R P   E  IV+ AP+FH  G SQ  L   L   +V R R+FD EAT+  +  HRA  LV
Sbjct: 238 RIPMPREDTIVMAAPIFHGTGLSQFGLGWGLGNKVVLRQRRFDAEATVAAVAEHRAATLV 297

Query: 289 VVPVMFDRIMELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEA 348
           +VP M  RI++L   VL RY   +LR   A+GS + PD+       FG+V+YN Y +TE 
Sbjct: 298 LVPTMLQRIIDLGPDVLGRYDTSSLRVIFAAGSALSPDLSKRTEEAFGEVLYNLYASTEV 357

Query: 349 GMIATATPADLRAAPDTAGRPAEGTEIRILDQEFNEVPE-GEVGSIFVCNDSQFDGYTSG 407
            + A ATP D+R AP T GRP  G  + I D++   + E G VG+IFV +   FDGYT G
Sbjct: 358 AVAAVATPRDMREAPGTVGRPPVGCRVAIYDEQRRRITEPGVVGTIFVSSGLSFDGYTDG 417

Query: 408 TTKDFHAGFMSSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAA 467
             K+   G +SSGDVG+ D  GRLF+ GRDD+MIVSGGENV+P+EVE  L   P+V EAA
Sbjct: 418 RNKEIVDGLLSSGDVGHFDAEGRLFIDGRDDDMIVSGGENVFPLEVENLLVERPDVLEAA 477

Query: 468 VIGVDDEQYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRG 527
           V+GV D  +G RL AFVV    A  D    P+ ++ +V+ NLA +KVPR++  LDELPR 
Sbjct: 478 VVGVPDRDFGTRLRAFVVPAEGAARD----PQEIRDYVKANLARHKVPRDVVFLDELPRN 533

Query: 528 STGKILRAEL 537
           +TGK+LR  L
Sbjct: 534 ATGKLLRRVL 543


>tr|D1A3M5|D1A3M5_THECU Tax_Id=471852 SubName: Full=AMP-dependent
           synthetase and ligase;[Thermomonospora curvata DSM
           43183]
          Length = 527

 Score =  398 bits (1023), Expect = e-109
 Identities = 230/531 (43%), Positives = 303/531 (57%), Gaps = 11/531 (2%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           RI Q+L  +T   R+GLI  + P        A+R  G            R   R  LVDE
Sbjct: 3   RIRQVLEGLTAARRAGLIG-LPPRAVAPSIRALRAYGPLGAAATMNAL-RFGSRTALVDE 60

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
            GTLT+  L+ RSN           G    VGI+CRNHRG ++A+ AA +IGA +L LNT
Sbjct: 61  HGTLTFADLERRSNALANAWRARGLGPASRVGILCRNHRGLLDAMTAAAKIGAGVLFLNT 120

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
            F GP L   V REGV  +++DEEFT     A    PQ  R VAW+D      +E+L+  
Sbjct: 121 DFGGPQLVQTVEREGVTALVHDEEFTPVAAGA--PAPQG-RFVAWTDRPGGGDLERLIAE 177

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
                P   GR G L++LTSGT+G PKGA              I+ R P+R  + + +  
Sbjct: 178 GDPAPPPAPGRHGSLVILTSGTSGAPKGAPRSSGPSAAWLPVGIVHRIPFRPGESVFVGP 237

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFH WG + +++       ++ RR+FD +A LDL++RHR   LV VPVM  R++    +
Sbjct: 238 PMFHGWGLTAMLVTLGTGSVLLLRRRFDADAVLDLLERHRVRALVAVPVMLSRLLAADAR 297

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
             NR   R LR  A  G+ + P +    M RFG V+YN Y +TEA  I+ ATP DLRAAP
Sbjct: 298 RENRPRLR-LRIIATGGAALSPALAERVMARFGPVLYNFYGSTEASSISIATPEDLRAAP 356

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
              GRP  GT ++ILD    EVP G  G I + +  +F GYT G TK      M+ GD+G
Sbjct: 357 GCVGRPTLGTTVKILDASGREVPPGVTGQIHIDSPLRFAGYTGGGTKPTAGKLMAVGDLG 416

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
           +LD  GRLF+ GR D+MIVSGGENVYP EVE+ LA HP + EAAV+GV DE++GQRL A+
Sbjct: 417 HLDAAGRLFIDGRADDMIVSGGENVYPAEVEELLAGHPGIREAAVVGVPDEEFGQRLRAY 476

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILR 534
           VV       D     E ++++V  NLA YKVPR++  ++ELPR STGK+L+
Sbjct: 477 VVA-----ADTALGEEEVRRYVSANLARYKVPRDVVFVEELPRTSTGKVLK 522


>tr|C1AJU6|C1AJU6_MYCBT Tax_Id=561275 (fadD2)SubName: Full=Acyl-CoA
           synthetase; EC=2.3.1.86;[Mycobacterium bovis]
          Length = 560

 Score =  398 bits (1022), Expect = e-108
 Identities = 230/536 (42%), Positives = 315/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            + + V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGEGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|A1KF91|A1KF91_MYCBP Tax_Id=410289 (fadD2)SubName: Full=Probable
           fatty-acid-CoA ligase fadD2; EC=6.2.1.-;[Mycobacterium
           bovis]
          Length = 560

 Score =  398 bits (1022), Expect = e-108
 Identities = 230/536 (42%), Positives = 315/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            + + V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGEGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|Q7U2E6|Q7U2E6_MYCBO Tax_Id=1765 (fadD2)SubName: Full=PROBABLE
           FATTY-ACID-COA LIGASE FADD2 (FATTY-ACID-COA SYNTHETASE)
           (FATTY-ACID-COA SYNTHASE); EC=6.2.1.-;[Mycobacterium
           bovis]
          Length = 560

 Score =  397 bits (1020), Expect = e-108
 Identities = 230/536 (42%), Positives = 314/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            +   V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|P95227|P95227_MYCTU Tax_Id=1773 (fadD2)SubName: Full=PROBABLE
           FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE)
           (FATTY-ACID-CoA SYNTHASE); EC=6.2.1.-; SubName:
           Full=Substrate--CoA ligase;[Mycobacterium tuberculosis]
          Length = 560

 Score =  397 bits (1020), Expect = e-108
 Identities = 230/536 (42%), Positives = 314/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            +   V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|C6DRS8|C6DRS8_MYCTK Tax_Id=478434 SubName: Full=Fatty-acid-CoA
           ligase fadD2;[Mycobacterium tuberculosis]
          Length = 560

 Score =  397 bits (1020), Expect = e-108
 Identities = 230/536 (42%), Positives = 314/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            +   V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|A5TYZ6|A5TYZ6_MYCTA Tax_Id=419947 (fadD2)SubName:
           Full=Fatty-acid-CoA ligase FadD2;[Mycobacterium
           tuberculosis]
          Length = 560

 Score =  397 bits (1020), Expect = e-108
 Identities = 230/536 (42%), Positives = 314/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            +   V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|A5WIX8|A5WIX8_MYCTF Tax_Id=336982 SubName: Full=Fatty-acid-CoA
           ligase fadD2;[Mycobacterium tuberculosis]
          Length = 560

 Score =  397 bits (1020), Expect = e-108
 Identities = 230/536 (42%), Positives = 314/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            +   V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|A4KNT6|A4KNT6_MYCTU Tax_Id=395095 SubName: Full=Fatty-acid-CoA
           ligase fadD2;[Mycobacterium tuberculosis str. Haarlem]
          Length = 560

 Score =  397 bits (1020), Expect = e-108
 Identities = 230/536 (42%), Positives = 314/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            +   V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|A2VNI4|A2VNI4_MYCTU Tax_Id=348776 SubName: Full=Fatty-acid-CoA
           ligase fadD2;[Mycobacterium tuberculosis C]
          Length = 560

 Score =  397 bits (1020), Expect = e-108
 Identities = 230/536 (42%), Positives = 314/536 (58%), Gaps = 13/536 (2%)

Query: 9   LGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLT 68
           L  +  +  SG I    P  Y  +AA +R+ G           +R P+R  ++DE GTLT
Sbjct: 30  LHYLRKIIESGAIGLEPPLNYAALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLT 88

Query: 69  WRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGP 128
           + +LDE ++            +   V I+ RNHR FV A   A R+GA I+LLN+ F+GP
Sbjct: 89  FSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGP 148

Query: 129 ALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWSD---GQHDLTVEQLVNA 183
            + +V  REG   +IYD+E+T  V  A    G+ +A  +    D   G  D T+ +L+ A
Sbjct: 149 QIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELI-A 207

Query: 184 HLGDQPE-RTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIV 242
           H    P  +  R   +I+LTSGTTGTPKGA           +  IL   P++A +  ++ 
Sbjct: 208 HSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAP-IGGILSHVPFKAGEVTLLP 266

Query: 243 APMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPT 302
           +PMFHA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++   
Sbjct: 267 SPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLE 326

Query: 303 KVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAA 362
           K   +    +L+    SGS++  ++    +   G VIYN Y +TE      A P DL+  
Sbjct: 327 KTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFN 386

Query: 363 PDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDV 422
           P T G   +G  ++ILD+  NEVP+G VG IFV N   F+GYT G  K    G +SSGDV
Sbjct: 387 PSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDV 446

Query: 423 GYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAA 482
           GY D  G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EAA IGVDD+++G RL A
Sbjct: 447 GYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRA 506

Query: 483 FVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           FVV +P ADLDE    +T+KQ+VRD+LA YKVPRE+  LDELPR  TGK+L+ EL+
Sbjct: 507 FVVKKPGADLDE----DTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELR 558


>tr|Q5YT49|Q5YT49_NOCFA Tax_Id=37329 SubName: Full=Putative acyl-CoA
           synthetase;[Nocardia farcinica]
          Length = 541

 Score =  392 bits (1007), Expect = e-107
 Identities = 226/517 (43%), Positives = 295/517 (57%), Gaps = 9/517 (1%)

Query: 17  RSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLTWRQLDERS 76
           R+GL+ P RPDR   +  A+ R G+           R  DR  ++DE G +++R+LDER+
Sbjct: 26  RAGLLTPERPDRLAGMGLAVVRSGLLGGLVGVAAV-RYRDRTAVLDERGRVSFRELDERT 84

Query: 77  NXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGPALADVVAR 136
                          + V ++ RNHRGF  A+ AA + GA I+L+NT F    L +V+AR
Sbjct: 85  TALANAWRARGLRDGEGVAVLTRNHRGFHYAVFAAAKCGARIILVNTDFGAGQLREVLAR 144

Query: 137 EGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNAHLGDQPERTGRTG 196
           EG D V++DEEFT  +    D RP+  R  AW+D     T++ L+         R     
Sbjct: 145 EGADLVVHDEEFTGLLG---DLRPRRGRYRAWTDAPAVDTLDNLIAGGARTPARRPRTPA 201

Query: 197 RLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMFHAWGFSQLVL 256
           R++LLTSGTTGTPKGA           L  +L R P R  +     AP+FH  GF+  VL
Sbjct: 202 RIVLLTSGTTGTPKGAPRREPTSLSP-LGGLLARVPLRVREVTECPAPLFHTLGFAHAVL 260

Query: 257 AASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLNRYSGRTLRFA 316
           A     T+V RRKFDPEA LD + RHRA+ LVVVPVM  R+++             LR  
Sbjct: 261 ALGFGTTLVIRRKFDPEAVLDSLVRHRASTLVVVPVMLRRLVDADPHARAHRELSRLRVV 320

Query: 317 AASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTAGRPAEGTEIR 376
             +GS++   + +     FG V+YN Y +TEA     ATPADL  AP   GRP  G  + 
Sbjct: 321 FVAGSQLGAPLCLRATEAFGPVLYNVYGSTEAAYATIATPADLAEAPGCVGRPVPGAVVA 380

Query: 377 ILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLDRNGRLFVVGR 436
           ILD    E+P G  G IFV ND QF+GYT G  K    G M++GD+G++D  GRLFV GR
Sbjct: 381 ILDAADRELPAGHTGRIFVGNDYQFEGYTGGGDKPRVRGLMATGDLGHVDAAGRLFVDGR 440

Query: 437 DDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVLEPDADLDENA 496
           +D+MIVSGGENV+P EVE  LA HP VAEA+  GVDD++YGQRL   VVL P   L    
Sbjct: 441 EDDMIVSGGENVFPGEVEDLLAAHPAVAEASAFGVDDDEYGQRLRVAVVLRPGHAL---- 496

Query: 497 APETLKQHVRDNLANYKVPREIAVLDELPRGSTGKIL 533
             E ++ HVR +LA YKVPR++  L ELPR  +GK+L
Sbjct: 497 TAEQVRDHVRTHLARYKVPRDVLFLPELPRNPSGKVL 533


>tr|C4DGK4|C4DGK4_9ACTO Tax_Id=446470 SubName: Full=Acyl-CoA
           synthetase (AMP-forming)/AMP-acid ligase
           II;[Stackebrandtia nassauensis DSM 44728]
          Length = 530

 Score =  388 bits (996), Expect = e-105
 Identities = 211/521 (40%), Positives = 302/521 (57%), Gaps = 12/521 (2%)

Query: 13  TTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLTWRQL 72
           +T+AR GL+ P RPDR ++  + + R G+          +R P+   +VDE G +++ +L
Sbjct: 16  STMARRGLLTPGRPDRVVRQVSTLARWGLGLAGEFASAARRDPEWTAVVDEDGPVSFAEL 75

Query: 73  DERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGPALAD 132
           DER++             P  V ++CRNH G +  L+A  ++GAD +L NT  +   +  
Sbjct: 76  DERTDRLARVLAEGRPEGPPRVAVLCRNHTGMIATLIACGKLGADAVLFNTGLSAQQVRQ 135

Query: 133 VVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNAHLGDQPERT 192
            V    +  ++ D EF    D      P   R++A ++G     +  L  A         
Sbjct: 136 AVDDHDIAVLVADTEFLPLPDL-----PDGVRVIA-AEGDGADGLRALAEAAEPGGHSPP 189

Query: 193 GRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMFHAWGFS 252
             TGR I+LTSGTTGTPKGA+         +L A+L R P +    I I AP+FH WG++
Sbjct: 190 AATGRTIVLTSGTTGTPKGARRPKPALH--SLTALLSRIPLKVGDRIHIAAPIFHTWGYA 247

Query: 253 QLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLNRYSGRT 312
            L LA ++  TIV RR+FDPE +L  +  H  T +  VPVM  R++ELP +V +     +
Sbjct: 248 ALQLAIAMRATIVLRRRFDPEPSLRTLSEHDCTAMFAVPVMLQRLLELPPEVRDGCDTAS 307

Query: 313 LRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTAGRPAEG 372
           LR  A SGS    D+   FM+ FGDV+YN Y  TE   I+ ATP +LRA PDT+GRP  G
Sbjct: 308 LRVVATSGSSYPGDLATRFMDAFGDVLYNLYGTTEVSWISIATPEELRAHPDTSGRPPHG 367

Query: 373 TEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLDRNGRLF 432
           T + +LD++  EV  G  G IFV N+  F+GYT G+ +    G M SGD+G+ D +G L+
Sbjct: 368 TTVLLLDEDGREVDRGVPGRIFVGNEMLFEGYTDGSRRSTFDGTMDSGDLGHRDESGLLY 427

Query: 433 VVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVLEPDADL 492
           V GR D+MI+SGGENV+P EVE  LA  P+V E AV+GV DE++GQRL A VV+    +L
Sbjct: 428 VDGRADDMIISGGENVFPSEVENLLARLPQVREVAVVGVADEEFGQRLVAHVVVAEGHEL 487

Query: 493 DENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKIL 533
           D     ET++ HVR +LA + VPR++  L++LPR +TGK++
Sbjct: 488 D----AETVRDHVRTHLARFSVPRDVRFLEQLPRNATGKVV 524


>tr|C4RJJ4|C4RJJ4_9ACTO Tax_Id=219305 SubName: Full=Acyl-CoA
           synthetase;[Micromonospora sp. ATCC 39149]
          Length = 546

 Score =  385 bits (989), Expect = e-105
 Identities = 222/537 (41%), Positives = 310/537 (57%), Gaps = 22/537 (4%)

Query: 3   PRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVD 62
           PR+D +   + TL R GL+ P RP R      A+RR G            R PDR  +VD
Sbjct: 25  PRMD-LPFTVATLTRRGLLTPGRPIRVAAQLNALRRWGWNLAGELRQAAARDPDRTAVVD 83

Query: 63  ELGT-LTWRQLDERSNXXXXXXXXXXXGSP-KVVGIMCRNHRGFVEALVAANRIGADILL 120
           E GT LT+  L +R+             +P   +G++CRNH G VEA+VA+  +GAD +L
Sbjct: 84  ERGTELTYGALLDRAERLAKSLRSVFGVAPGDPIGLLCRNHHGLVEAVVASTLLGADAVL 143

Query: 121 LNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQL 180
           +NT  +   LA V   +G+  +++D EF    +R      +  R+        +  +E+L
Sbjct: 144 VNTGLSPAQLATVAEEQGLKVLVHDAEFA---ERTLGLPAELHRV-------DEARLEEL 193

Query: 181 VNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIV 240
           V A      +   R GR ++LTSGTTG PKGA+          L +I+DR P      ++
Sbjct: 194 VAAAPPSDLQPPPREGRTVVLTSGTTGAPKGARRPTPHGFGP-LVSIIDRIPLHVRDTVM 252

Query: 241 IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL 300
           I AP+FH WG++ L +  +L  TIV  R+FDP ATLD +  HR   +  VPVM  R+ME+
Sbjct: 253 IAAPLFHTWGYAALQVCFALRATIVLHRRFDPAATLDALAAHRCDAMFAVPVMVQRLMEV 312

Query: 301 PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR 360
           P           L+  A SGS +   + + FM+ +GDV+YN Y +TE    + A P +LR
Sbjct: 313 PPPEQKP----PLKVVALSGSALPGGLALRFMDAYGDVLYNLYGSTEVSWASIAGPTELR 368

Query: 361 AAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSG 420
           AAP TAGRP  GT++R+LD E   VP G+VG IFV N+  F+GYTSG  ++   G + +G
Sbjct: 369 AAPTTAGRPPHGTQLRVLDDEGRPVPTGQVGRIFVGNEMLFEGYTSGAARESRDGLLDTG 428

Query: 421 DVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRL 480
           D+G ++ +G LFV GR D+MIVSGGENV+P EVE  +A  P+V E AVIGV DE+YGQRL
Sbjct: 429 DLGRVNADGLLFVDGRADDMIVSGGENVFPSEVEDLVARLPQVREVAVIGVPDEEYGQRL 488

Query: 481 AAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAEL 537
           AAF+ L P   LD    PE ++++VR  LA + VPR++  +  LPR +TGK+L  EL
Sbjct: 489 AAFLALHPGETLD----PEAVREYVRHYLAQFSVPRDVVFVKYLPRNATGKVLTREL 541


>tr|D1A6A1|D1A6A1_THECU Tax_Id=471852 SubName: Full=AMP-dependent
           synthetase and ligase;[Thermomonospora curvata DSM
           43183]
          Length = 539

 Score =  383 bits (983), Expect = e-104
 Identities = 221/537 (41%), Positives = 302/537 (56%), Gaps = 12/537 (2%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           R + +L +    A SGL  P  P +  +   A+RR G            R P R  +VDE
Sbjct: 10  RAETMLRVAAMFASSGLWRPGPPLKVARQLDALRRWGTTLGGSLVSAAARDPGRAAIVDE 69

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
            GTLT+ Q+D R++           G+   V ++CRNHRG VE+LVA +++G+D++LLNT
Sbjct: 70  YGTLTYAQVDARTDRLAAALGDG--GARPRVAVLCRNHRGMVESLVACSKLGSDVVLLNT 127

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
             +      V+  + V+ +I D EF   +     G P A R +  +DG      E +   
Sbjct: 128 GMSAEQSLKVLDEQQVEVLIADSEFAEVLK----GAPAAVRTLT-ADGPGSAVAELIDRT 182

Query: 184 HLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVA 243
            L         +GR I+L+SGTTG PKGA           L ++L R P R  + ++I A
Sbjct: 183 VLKAPLTPPPHSGRTIVLSSGTTGQPKGAGRHSRPGLGP-LASVLSRIPLRVHETMLIEA 241

Query: 244 PMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTK 303
           PMFH WG++ L +A  L  T+V RR+FDP A L      RAT L+ VP+M  R++E  + 
Sbjct: 242 PMFHTWGYAALQIALGLRATMVLRRRFDPAAGLRTAAETRATALIAVPIMAQRMLEWRSS 301

Query: 304 VLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAP 363
                    LR  A SGS +       FM+ FGDV+YN Y +TEA  +  ATP DLR  P
Sbjct: 302 TQEELDLSALRIVALSGSALPGGFATRFMDAFGDVLYNLYGSTEASWVTIATPRDLRRHP 361

Query: 364 DTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVG 423
           DTAGRP  GT + ILD+E   VP G VG IF  N+  F GYTSG TK+   G +S GD+G
Sbjct: 362 DTAGRPPRGTRLAILDEEGRPVPPGTVGRIFAANELLFTGYTSGATKETVDGMISLGDLG 421

Query: 424 YLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAF 483
            +D +G LFV GR D+MIVSGGENV+P EVE  L+   +V E AV+GV DE++GQRLAA 
Sbjct: 422 RIDEDGLLFVQGRSDDMIVSGGENVFPGEVEDALSELEQVREVAVVGVPDEEFGQRLAAH 481

Query: 484 VVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAK 540
           VVL P A+L      + ++ H R  +  + VPR++    ELPR +TGK+LR +L+A+
Sbjct: 482 VVLHPGAEL----TADQVRDHARRRVGRFAVPRDVYFPSELPRNATGKVLRRQLRAE 534


>tr|Q9CD27|Q9CD27_MYCLE Tax_Id=1769 (fadD2)SubName: Full=Acyl-CoA
           synthase;[Mycobacterium leprae]
          Length = 548

 Score =  381 bits (978), Expect = e-103
 Identities = 216/532 (40%), Positives = 302/532 (56%), Gaps = 11/532 (2%)

Query: 12  ITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLTWRQ 71
           + ++  SG +    P  Y  +A AMR+ G           +R P R  L+DE GTLT+++
Sbjct: 18  LRSIFESGALGFEPPLTYAAMAVAMRKWG-DLAMLPAMPARRSPHRAALIDEEGTLTYKE 76

Query: 72  LDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGPALA 131
           LD  ++                + I+ RNHR FV A     R+GA I+LLN+ F+GP + 
Sbjct: 77  LDRAAHALANGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQIK 136

Query: 132 DVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSD-----GQHDLTVEQLVNAHLG 186
           +V  REG   +IYD+E+T  V +A     +   +    D     G  D T+ +L+     
Sbjct: 137 EVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIARSSS 196

Query: 187 DQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMF 246
               +  +   +I+LTSGTTGTPKGA           L  IL + P+RA +  ++ APMF
Sbjct: 197 APAPKVRKRASIIILTSGTTGTPKGANRNTPASLAP-LGGILSKVPFRAHEVTLLPAPMF 255

Query: 247 HAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLN 306
           HA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++    +  
Sbjct: 256 HALGYLHATLAMFLGSTLVLRRRFKPATVLEDIEKHQATAMVVVPVMLSRILDTLENLET 315

Query: 307 RYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTA 366
           +    +LR    SGS++  ++    +   G VIYN Y +TE      A P DL+    T 
Sbjct: 316 KSDLSSLRVVFVSGSQLGAELATRALEELGPVIYNMYGSTEIAFATIAGPKDLQINSATV 375

Query: 367 GRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLD 426
           G   +G +++ILD    EVP G+VG IFV N   F+GYT G  K    G +SSGDVGY D
Sbjct: 376 GPVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFD 435

Query: 427 RNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVL 486
            +  L++ GRDDEMIVSGGENV+P EVE  ++ HPEV EA  IGVDD+++G RL AFVV 
Sbjct: 436 EHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVK 495

Query: 487 EPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           + DA +DE+A    +K +VRD+LA YKVPRE+  L+ELPR  TGK+L+ EL+
Sbjct: 496 KQDATIDEDA----IKAYVRDHLARYKVPREVIFLEELPRNPTGKVLKRELR 543


>tr|B8ZTD6|B8ZTD6_MYCLB Tax_Id=561304 (fadD2)SubName: Full=Acyl-CoA
           synthase;[Mycobacterium leprae]
          Length = 548

 Score =  381 bits (978), Expect = e-103
 Identities = 216/532 (40%), Positives = 302/532 (56%), Gaps = 11/532 (2%)

Query: 12  ITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDELGTLTWRQ 71
           + ++  SG +    P  Y  +A AMR+ G           +R P R  L+DE GTLT+++
Sbjct: 18  LRSIFESGALGFEPPLTYAAMAVAMRKWG-DLAMLPAMPARRSPHRAALIDEEGTLTYKE 76

Query: 72  LDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFAGPALA 131
           LD  ++                + I+ RNHR FV A     R+GA I+LLN+ F+GP + 
Sbjct: 77  LDRAAHALANGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQIK 136

Query: 132 DVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSD-----GQHDLTVEQLVNAHLG 186
           +V  REG   +IYD+E+T  V +A     +   +    D     G  D T+ +L+     
Sbjct: 137 EVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIARSSS 196

Query: 187 DQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMF 246
               +  +   +I+LTSGTTGTPKGA           L  IL + P+RA +  ++ APMF
Sbjct: 197 APAPKVRKRASIIILTSGTTGTPKGANRNTPASLAP-LGGILSKVPFRAHEVTLLPAPMF 255

Query: 247 HAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLN 306
           HA G+    LA  L  T+V RR+F P   L+ I++H+AT +VVVPVM  RI++    +  
Sbjct: 256 HALGYLHATLAMFLGSTLVLRRRFKPATVLEDIEKHQATAMVVVPVMLSRILDTLENLET 315

Query: 307 RYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTA 366
           +    +LR    SGS++  ++    +   G VIYN Y +TE      A P DL+    T 
Sbjct: 316 KSDLSSLRVVFVSGSQLGAELATRALEELGPVIYNMYGSTEIAFATIAGPKDLQINSATV 375

Query: 367 GRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLD 426
           G   +G +++ILD    EVP G+VG IFV N   F+GYT G  K    G +SSGDVGY D
Sbjct: 376 GPVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFD 435

Query: 427 RNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVL 486
            +  L++ GRDDEMIVSGGENV+P EVE  ++ HPEV EA  IGVDD+++G RL AFVV 
Sbjct: 436 EHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVK 495

Query: 487 EPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQ 538
           + DA +DE+A    +K +VRD+LA YKVPRE+  L+ELPR  TGK+L+ EL+
Sbjct: 496 KQDATIDEDA----IKAYVRDHLARYKVPREVIFLEELPRNPTGKVLKRELR 543


>tr|Q0S2R2|Q0S2R2_RHOSR Tax_Id=101510 SubName: Full=Probable
           O-succinylbenzoate--CoA ligase; EC=6.2.1.26;[Rhodococcus
           sp.]
          Length = 544

 Score =  380 bits (977), Expect = e-103
 Identities = 226/543 (41%), Positives = 305/543 (56%), Gaps = 24/543 (4%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           +I   +G +  + R+GL+   R D+ ++   A+R+ G           +   D   L+DE
Sbjct: 9   KITDTVGAVRVMNRAGLVPFPRVDQGVRSILAVRKFG-PFAGPVHANAEAGLDAVALIDE 67

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
            G LT+  ++E+SN               V+G MCRNHRG V  ++AA + G  ++L+NT
Sbjct: 68  RGPLTYTDIEEQSNALVRAWQADGITPGSVMGCMCRNHRGLVLTMLAAAKNGTKLVLMNT 127

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
            FA P L DV ARE V   +YD+EF A  +   D       ++A+     D +  Q+   
Sbjct: 128 GFARPQLVDVAAREQVQAFVYDDEFHAVAEALPD------EVIAYRSWVEDDSTSQVRT- 180

Query: 184 HLGDQPERTGRT--------GRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRA 235
            L D  E   R+        G  +LLTSGTTGTPKGA               LDR P R 
Sbjct: 181 -LDDVMEGRDRSSLPAPSTQGGFVLLTSGTTGTPKGAPRGHTSPLASA--QFLDRVPLRR 237

Query: 236 EQPIVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFD 295
            Q +++ AP FH  G SQ  LA +L  T+V  RKFDPE T+ L+++HR   LVVVP M  
Sbjct: 238 GQTMMMAAPAFHGTGVSQFALALALGQTVVMHRKFDPENTIRLVEKHRCDTLVVVPTMLQ 297

Query: 296 RIMELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATAT 355
           RI++L  + L +Y   +L+   A+GS + PD+       FG+V++N Y +TE  +   AT
Sbjct: 298 RIIDLGPETLAKYDTSSLKIIFAAGSALSPDLCKRTTAAFGEVLHNLYGSTEVAVATVAT 357

Query: 356 PADLRAAPDTAGRPAEGTEIRILDQEFNEVPEGE-VGSIFVCNDSQFDGYTSGTTKDFHA 414
           PADL  AP TAGR      + + D+    + E E VG IFV +   F GYT G  K+   
Sbjct: 358 PADLALAPGTAGRAPVTCHVELYDESGQRITEPETVGRIFVASGLSFAGYTDGRDKERIN 417

Query: 415 GFMSSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDE 474
           G +S+GDVG+ DRNG LFV GRDD+MIVSGGENVYP+EVE  LA   +V EAAVIGV+D 
Sbjct: 418 GLLSTGDVGHFDRNGLLFVDGRDDDMIVSGGENVYPLEVENLLADREDVLEAAVIGVEDS 477

Query: 475 QYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILR 534
           ++G RL AFVV  P +  D     + LK HV+ NLA YKVPREI  ++ELPR +TGK+LR
Sbjct: 478 EFGHRLRAFVVPGPGSAKD----ADELKAHVKSNLARYKVPREIIFIEELPRNATGKLLR 533

Query: 535 AEL 537
             L
Sbjct: 534 RVL 536


>tr|B2HNV0|B2HNV0_MYCMM Tax_Id=216594 (fadD2)SubName:
           Full=Fatty-acid-CoA ligase FadD2;[Mycobacterium marinum]
          Length = 557

 Score =  380 bits (975), Expect = e-103
 Identities = 211/492 (42%), Positives = 293/492 (59%), Gaps = 10/492 (2%)

Query: 52  QRCPDRPGLVDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAA 111
           +R P R   +DE G  T++QLDE ++            +   V I+ RNHR F+ A   A
Sbjct: 66  RRHPHRAACIDEEGEFTYQQLDEAAHAVANALLAKGVSAGDGVAILARNHRWFLIANYGA 125

Query: 112 NRIGADILLLNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWS 169
            R GA I+LLN+ F+GP + +V  REG   +IYD+E+T  V +A    G+ +A  +   S
Sbjct: 126 ARAGARIILLNSEFSGPQIKEVSEREGAKLIIYDDEYTGAVSKAEPPLGKLRALGVNPDS 185

Query: 170 D---GQHDLTVEQLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKA 226
           +   G  D T+ +L+         + G+   +I+LTSGTTGTPKGA           +  
Sbjct: 186 EEDSGSTDETLAELIARSSTAPAPKAGKHASIIILTSGTTGTPKGANRSTPPTLAP-VGG 244

Query: 227 ILDRTPWRAEQPIVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATG 286
           IL   P++A +   + APMFHA G+    +A  L  T+V RRKF P+  L+ I++H+ T 
Sbjct: 245 ILSHVPFKANEVTSLPAPMFHALGYLHATIAMFLGSTLVLRRKFKPQLVLEDIEKHKVTA 304

Query: 287 LVVVPVMFDRIMELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNAT 346
           +VVVPVM  R+++   K+  +    +L+    SGS++  ++    +   G VIYN Y +T
Sbjct: 305 MVVVPVMLSRLLDAVEKIDKKPDLSSLKIVFVSGSQLGAELASRALKDLGPVIYNMYGST 364

Query: 347 EAGMIATATPADLRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTS 406
           E      A P DL+    T G   +G +++ILD   NEV +G+VG IFV N   F+GYT 
Sbjct: 365 EIAFATIAGPEDLQRNAATVGPVVKGVKVKILDDNGNEVSQGQVGRIFVGNAFPFEGYTG 424

Query: 407 GTTKDFHAGFMSSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEA 466
           G  K    G MSSGDVGY D +G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EA
Sbjct: 425 GGHKQIIDGLMSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEA 484

Query: 467 AVIGVDDEQYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPR 526
             +GVDD+++G RL AFVV +PD DLDE    ET+K +VRD+LA YKVPRE+  L+ELPR
Sbjct: 485 TALGVDDKEWGARLRAFVVKKPDTDLDE----ETVKHYVRDHLARYKVPREVIFLEELPR 540

Query: 527 GSTGKILRAELQ 538
             TGKIL+ EL+
Sbjct: 541 NPTGKILKRELR 552


>tr|A0PN48|A0PN48_MYCUA Tax_Id=362242 (fadD2)SubName:
           Full=Fatty-acid-CoA ligase FadD2;[Mycobacterium
           ulcerans]
          Length = 557

 Score =  379 bits (974), Expect = e-103
 Identities = 211/492 (42%), Positives = 292/492 (59%), Gaps = 10/492 (2%)

Query: 52  QRCPDRPGLVDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAA 111
           +R P R   +DE G  T++QLDE  +            +   V I+ RNHR F+ A   A
Sbjct: 66  RRHPHRAACIDEEGEFTYQQLDEAGHAVANALLAKGVSAGDGVAILARNHRWFLIANYGA 125

Query: 112 NRIGADILLLNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFD--GRPQATRIVAWS 169
            R GA I+LLN+ F+GP + +V  REG   +IYD+E+T  V +A    G+ +A  +   S
Sbjct: 126 ARAGARIILLNSEFSGPQIKEVSEREGAKLIIYDDEYTGAVSKAEPPLGKLRALGVNPDS 185

Query: 170 D---GQHDLTVEQLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKA 226
           +   G  D T+ +L+         + G+   +I+LTSGTTGTPKGA           +  
Sbjct: 186 EEDSGSTDETLAELIARSSTAPAPKAGKHASIIILTSGTTGTPKGANRSTPPTLAP-VGG 244

Query: 227 ILDRTPWRAEQPIVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATG 286
           IL   P++A +   + APMFHA G+    +A  L  T+V RRKF P+  L+ I++H+ T 
Sbjct: 245 ILSHVPFKANEVTSLPAPMFHALGYLHATIAMFLGSTLVLRRKFKPQLVLEDIEKHKVTA 304

Query: 287 LVVVPVMFDRIMELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNAT 346
           +VVVPVM  R+++   K+  +    +L+    SGS++  ++    +   G VIYN Y +T
Sbjct: 305 MVVVPVMLSRLLDAVEKIDKKPDLSSLKIVFVSGSQLGAELASRALKDLGPVIYNMYGST 364

Query: 347 EAGMIATATPADLRAAPDTAGRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTS 406
           E      A P DL+    T G   +G +++ILD   NEV +G+VG IFV N   F+GYT 
Sbjct: 365 EIAFATIAGPEDLQRNAATVGPVVKGVKVKILDDNGNEVSQGQVGRIFVGNAFPFEGYTG 424

Query: 407 GTTKDFHAGFMSSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEA 466
           G  K    G MSSGDVGY D +G L+V GRDDEMIVSGGENV+P EVE  ++ HP+V EA
Sbjct: 425 GGHKQIIDGLMSSGDVGYFDEHGLLYVSGRDDEMIVSGGENVFPAEVEALISGHPDVVEA 484

Query: 467 AVIGVDDEQYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPR 526
             +GVDD+++G RL AFVV +PD DLDE    ET+K +VRD+LA YKVPRE+  L+ELPR
Sbjct: 485 TALGVDDKEWGARLRAFVVKKPDTDLDE----ETVKHYVRDHLARYKVPREVIFLEELPR 540

Query: 527 GSTGKILRAELQ 538
             TGKIL+ EL+
Sbjct: 541 NPTGKILKRELR 552


>tr|A3THW2|A3THW2_9MICO Tax_Id=313589 SubName: Full=Putative
           Acyl-CoA synthetase;[Janibacter sp. HTCC2649]
          Length = 525

 Score =  379 bits (974), Expect = e-103
 Identities = 214/535 (40%), Positives = 310/535 (57%), Gaps = 16/535 (2%)

Query: 8   ILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDEL-GT 66
           +L + T +A+ G++AP  P R +    ++ + G            R P +  ++DEL G+
Sbjct: 5   LLTVGTVMAKRGMLAPGPPHRQISQLRSLHKWGFGLAGELRQAAHRSPKQIAVIDELRGS 64

Query: 67  LTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNTAFA 126
           +T+ +L  RS               + +G++ RNH G +E +  A+ +G D++L+NT  +
Sbjct: 65  VTYGELLARSEQVSELLSARGFRPGQRLGLLARNHVGAIEIMTGASAVGIDLVLMNTGLS 124

Query: 127 GPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNAHLG 186
              LA V  ++ +  +I+D+EF   V       P A  ++  SD      V +L  A + 
Sbjct: 125 AGQLALVAGQQELTALIHDDEFDGVVGEL----PDAITVIRESDW-----VAELNAAPVA 175

Query: 187 DQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIVIVAPMF 246
                  + GR I+LTSGTTGTPKGA           + +I++R P  AE  I+I AP+F
Sbjct: 176 TSLAPPAKGGRTIILTSGTTGTPKGAARKTPGGFGPLI-SIIERIPLHAEDRILISAPIF 234

Query: 247 HAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMELPTKVLN 306
           H WG++ + L+ +L  TIV +R+FDP+A  DL++      +  +PVM  R+MELP     
Sbjct: 235 HTWGYAAMQLSFALRATIVLQRRFDPQAAKDLLEMKACHAMFAIPVMLQRMMELPADPAG 294

Query: 307 RYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLRAAPDTA 366
           +     LR  A SGS         FM+ +GDV+YN Y +TEA  I  ATP ++R  PDTA
Sbjct: 295 KKRRPNLRTVATSGSAYPHGFTTKFMDEYGDVLYNLYGSTEASWICIATPENMRRDPDTA 354

Query: 367 GRPAEGTEIRILDQEFNEVPEGEVGSIFVCNDSQFDGYTSGTTKDFHAGFMSSGDVGYLD 426
           G P  GT ++ILD + NEV  GE G IF  ND  FDGYTSG+TKDF  G +S+GD+G+ +
Sbjct: 355 GTPPLGTVVKILDADNNEVTPGETGRIFCGNDLVFDGYTSGSTKDFVDGLVSTGDMGH-E 413

Query: 427 RNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQRLAAFVVL 486
           ++G  +V GRDD+MIVSGGENVYPIEVE  L  HP V E +V+GV D  +GQRLAAF+ L
Sbjct: 414 KDGLFYVDGRDDDMIVSGGENVYPIEVESLLVDHPAVREVSVVGVPDPDFGQRLAAFIAL 473

Query: 487 EPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAELQAKV 541
              A L    + + +K HV+++ A + VPRE+  L+ELPR +TGKIL  EL+A +
Sbjct: 474 NDGAQL----SADEVKAHVKEHRARHCVPREVHFLEELPRNATGKILARELRASI 524


>tr|C0ZX64|C0ZX64_RHOE4 Tax_Id=234621 SubName: Full=Putative
           fatty-acid--CoA ligase; EC=6.2.1.-;[Rhodococcus
           erythropolis]
          Length = 544

 Score =  379 bits (973), Expect = e-103
 Identities = 221/544 (40%), Positives = 300/544 (55%), Gaps = 18/544 (3%)

Query: 1   MAPRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGL 60
           +  ++   +G    + R+GL+   R DR LK  AA+ + G           +   D   +
Sbjct: 4   LVTKVTDTIGAAGVMFRAGLVPFPRLDRGLKSIAAVDKYG-PFAGPVHAHAENGYDAVAI 62

Query: 61  VDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILL 120
           +DE G +T+ +L+ +SN            S  V+G MCRNHRG V  ++AA + G  ++L
Sbjct: 63  IDERGPITYAELERQSNALVRAWQADGITSDSVMGAMCRNHRGLVLTMLAAAKNGTKLVL 122

Query: 121 LNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFD------GRPQATRIVAWSDGQHD 174
           +NT FA P L DV ARE V   +YD+EF    D   D        P+ T     +DG   
Sbjct: 123 MNTGFARPQLVDVAAREKVVAFVYDDEFADIADALPDDVVVYRSWPEGTA----ADGSTA 178

Query: 175 LTVEQLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWR 234
            T+++ +            + G  +LLTSGTTGTPKGA               LDR P R
Sbjct: 179 ATLDEAIAGRTTSSVPAPEKNGGFVLLTSGTTGTPKGAPRGHTSPLASA--QFLDRVPLR 236

Query: 235 AEQPIVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMF 294
             Q +++ AP FH  G SQ  LA +L  T+V  RKFDPE T+ L+ +++   LVVVP M 
Sbjct: 237 RGQTMMMAAPAFHGTGVSQFALALALGQTVVMHRKFDPENTIKLVAQYKCDSLVVVPTML 296

Query: 295 DRIMELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATA 354
            RI++L   VL++Y    L+   ++GS + PD+       FG V+YN Y +TE  +   A
Sbjct: 297 TRIIDLGPDVLSKYDTSNLKIIFSAGSSLSPDLCKRVTASFGYVLYNLYGSTEVAVATVA 356

Query: 355 TPADLRAAPDTAGRPAEGTEIRILDQEFNEVPEGE-VGSIFVCNDSQFDGYTSGTTKDFH 413
           TP DL  AP TAGR      + + D+   ++     +G IFV +   F+GYT G  K+  
Sbjct: 357 TPEDLTIAPGTAGRAPVTCHVELFDENNKKITTPHTIGRIFVASGLSFEGYTDGRDKERI 416

Query: 414 AGFMSSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDD 473
            G +S+GDVG+ D NG LFV GRDD+MIVSGGENVYP+EVE  LA   +V EAAVIGV+D
Sbjct: 417 DGLLSTGDVGHFDANGLLFVDGRDDDMIVSGGENVYPLEVENLLADREDVLEAAVIGVED 476

Query: 474 EQYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKIL 533
             +G RL AFVV+   AD +     + LK HVR NLA YKVPREI  +DELPR +TGK+L
Sbjct: 477 ADFGHRLRAFVVVAHGADQNS----DELKDHVRSNLARYKVPREIVFIDELPRNATGKLL 532

Query: 534 RAEL 537
           R  L
Sbjct: 533 RRVL 536


>tr|C3JKR9|C3JKR9_RHOER Tax_Id=596309 SubName: Full=Acyl-CoA
           synthase;[Rhodococcus erythropolis SK121]
          Length = 544

 Score =  379 bits (973), Expect = e-103
 Identities = 221/544 (40%), Positives = 300/544 (55%), Gaps = 18/544 (3%)

Query: 1   MAPRIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGL 60
           +  ++   +G    + R+GL+   R DR LK  AA+ + G           +   D   +
Sbjct: 4   LVTKVTDTIGAAGVMFRAGLVPFPRLDRGLKSIAAVDKYG-PFAGPVHAHAENGYDAVAI 62

Query: 61  VDELGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILL 120
           +DE G +T+ +L+ +SN            S  V+G MCRNHRG V  ++AA + G  ++L
Sbjct: 63  IDERGPITYAELERQSNALVRAWQADGITSDSVMGAMCRNHRGLVLTMLAAAKNGTKLVL 122

Query: 121 LNTAFAGPALADVVAREGVDTVIYDEEFTATVDRAFD------GRPQATRIVAWSDGQHD 174
           +NT FA P L DV ARE V   +YD+EF    D   D        P+ T     +DG   
Sbjct: 123 MNTGFARPQLVDVAAREKVVAFVYDDEFADIADALPDDVVVYRSWPEGTA----ADGSTA 178

Query: 175 LTVEQLVNAHLGDQPERTGRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWR 234
            T+++ +            + G  +LLTSGTTGTPKGA               LDR P R
Sbjct: 179 ATLDEAIAGRTTSSVPAPEKNGGFVLLTSGTTGTPKGAPRGHTSPLASA--QFLDRVPLR 236

Query: 235 AEQPIVIVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMF 294
             Q +++ AP FH  G SQ  LA +L  T+V  RKFDPE T+ L+ +++   LVVVP M 
Sbjct: 237 RGQTMMMAAPAFHGTGVSQFALALALGQTVVMHRKFDPENTIKLVAQYKCDSLVVVPTML 296

Query: 295 DRIMELPTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATA 354
            RI++L   VL++Y    L+   ++GS + PD+       FG V+YN Y +TE  +   A
Sbjct: 297 TRIIDLGPDVLSKYDTSNLKIIFSAGSSLSPDLCKRVTASFGYVLYNLYGSTEVAVATVA 356

Query: 355 TPADLRAAPDTAGRPAEGTEIRILDQEFNEVPEGE-VGSIFVCNDSQFDGYTSGTTKDFH 413
           TP DL  AP TAGR      + + D+   ++     +G IFV +   F+GYT G  K+  
Sbjct: 357 TPEDLTIAPGTAGRAPVTCHVELFDENNKKITTPHTIGRIFVASGLSFEGYTDGRDKERI 416

Query: 414 AGFMSSGDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDD 473
            G +S+GDVG+ D NG LFV GRDD+MIVSGGENVYP+EVE  LA   +V EAAVIGV+D
Sbjct: 417 DGLLSTGDVGHFDANGLLFVDGRDDDMIVSGGENVYPLEVENLLADREDVLEAAVIGVED 476

Query: 474 EQYGQRLAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKIL 533
             +G RL AFVV+   AD +     + LK HVR NLA YKVPREI  +DELPR +TGK+L
Sbjct: 477 ADFGHRLRAFVVVAHGADQNS----DELKDHVRSNLARYKVPREIVFIDELPRNATGKLL 532

Query: 534 RAEL 537
           R  L
Sbjct: 533 RRVL 536


>tr|C1B1K5|C1B1K5_RHOOB Tax_Id=632772 SubName: Full=Putative
           acid--CoA ligase; EC=6.2.1.-;[Rhodococcus opacus]
          Length = 544

 Score =  378 bits (970), Expect = e-102
 Identities = 221/538 (41%), Positives = 299/538 (55%), Gaps = 14/538 (2%)

Query: 4   RIDQILGLITTLARSGLIAPMRPDRYLKIAAAMRREGMXXXXXXXXXXQRCPDRPGLVDE 63
           +I   +G +  + R+GL+   R D+ ++   A+R+ G           +   D   ++DE
Sbjct: 9   KIADTVGAVRVMNRAGLVPFPRVDQGVRSILAVRKYG-PFAGPVHANAEAGLDAVAIIDE 67

Query: 64  LGTLTWRQLDERSNXXXXXXXXXXXGSPKVVGIMCRNHRGFVEALVAANRIGADILLLNT 123
            G LT+  ++E+SN               V+G MCRNHRG V  ++AA + G  ++L+NT
Sbjct: 68  RGPLTYADIEEQSNALVRGWQADGITPGSVMGCMCRNHRGLVLTMLAAAKNGTKLVLMNT 127

Query: 124 AFAGPALADVVAREGVDTVIYDEEFTATVDRAFDGRPQATRIVAWSDGQHDLTVEQLVNA 183
            FA P L DV ARE V   +YD+EF A  +   D   +     +W++      V  L + 
Sbjct: 128 GFARPQLVDVAAREQVQAFVYDDEFHAVAEALPD---EVLVYRSWAEDDSTSRVRTLDDV 184

Query: 184 HLGDQPERT---GRTGRLILLTSGTTGTPKGAKHXXXXXXXXTLKAILDRTPWRAEQPIV 240
             G            G  +LLTSGTTGTPKGA               LDR P R  Q ++
Sbjct: 185 MEGRDRASLPAPSALGGFVLLTSGTTGTPKGAPRGHTSPLASA--QFLDRVPLRRGQTMM 242

Query: 241 IVAPMFHAWGFSQLVLAASLACTIVTRRKFDPEATLDLIDRHRATGLVVVPVMFDRIMEL 300
           + AP FH  G SQ  LA +L  T+   RKFDPE T+ L+++HR   LVVVP M  RI++L
Sbjct: 243 MAAPAFHGTGVSQFALALALGQTVAMHRKFDPENTIRLVEKHRCDTLVVVPTMLQRIIDL 302

Query: 301 PTKVLNRYSGRTLRFAAASGSRMRPDVVVAFMNRFGDVIYNNYNATEAGMIATATPADLR 360
             + L +Y   +L+   A+GS + PD+       FG V++N Y +TE  +   ATPADL 
Sbjct: 303 GPETLAKYDTSSLKIIFAAGSALSPDLCKRTTAAFGKVLHNLYGSTEVAVATVATPADLE 362

Query: 361 AAPDTAGRPAEGTEIRILDQEFNEVPEGE-VGSIFVCNDSQFDGYTSGTTKDFHAGFMSS 419
            AP TAGR      + + D+    + E E VG IFV +   F GYT G  K+   G +S+
Sbjct: 363 LAPGTAGRAPVTCHVELYDESSRRITEPETVGRIFVASGLSFSGYTDGRDKERINGLLST 422

Query: 420 GDVGYLDRNGRLFVVGRDDEMIVSGGENVYPIEVEKTLATHPEVAEAAVIGVDDEQYGQR 479
           GDVG+ DRNG LFV GRDD+MIVSGGENVYP+EVE  LA   +V EAAVIGV+D ++G R
Sbjct: 423 GDVGHFDRNGLLFVDGRDDDMIVSGGENVYPLEVENLLADREDVLEAAVIGVEDSEFGHR 482

Query: 480 LAAFVVLEPDADLDENAAPETLKQHVRDNLANYKVPREIAVLDELPRGSTGKILRAEL 537
           L AFVV  P +  D     E +K HV+ NLA YKVPREI  ++ELPR +TGK+LR  L
Sbjct: 483 LRAFVVPAPGSAKD----AEEMKAHVKSNLARYKVPREIIFIEELPRNATGKLLRRVL 536


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.320    0.137    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 3,896,859,576
Number of extensions: 163501326
Number of successful extensions: 453523
Number of sequences better than 10.0: 23561
Number of HSP's gapped: 398920
Number of HSP's successfully gapped: 27111
Length of query: 544
Length of database: 3,846,993,858
Length adjustment: 143
Effective length of query: 401
Effective length of database: 2,234,639,829
Effective search space: 896090571429
Effective search space used: 896090571429
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 83 (36.6 bits)