BLASTP 2.2.16 [Mar-25-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= MMAR_2868
         (365 letters)

Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr;
Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr;
trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr;
Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr;
Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr;
Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr;
Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr;
Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr;
Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr;
Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr;
Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr;
Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 
           11,275,203 sequences; 3,846,993,858 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits)  Value

tr|B2HE28|B2HE28_MYCMM Tax_Id=216594 (ribA1)SubName: Full=Ribofl...   636   e-180
tr|Q5SDQ2|Q5SDQ2_MYCMR Tax_Id=1781 (melJ)SubName: Full=Putative ...   636   e-180
tr|A0PS46|A0PS46_MYCUA Tax_Id=362242 (ribA1)SubName: Full=Ribofl...   634   e-180
tr|Q7TZ92|Q7TZ92_MYCBO Tax_Id=1765 (ribA1)SubName: Full=Probable...   448   e-124
tr|Q7D7R0|Q7D7R0_MYCTU Tax_Id=1773 (ribA1)SubName: Full=3,4-dihy...   448   e-124
tr|C1APL9|C1APL9_MYCBT Tax_Id=561275 (ribA1)SubName: Full=Putati...   448   e-124
tr|A5U3V9|A5U3V9_MYCTA Tax_Id=419947 (ribA1)SubName: Full=3,4-di...   448   e-124
tr|A1KK05|A1KK05_MYCBP Tax_Id=410289 (ribA1)SubName: Full=Probab...   448   e-124
tr|A5WNR5|A5WNR5_MYCTF Tax_Id=336982 SubName: Full=Riboflavin bi...   448   e-124
tr|A4KI84|A4KI84_MYCTU Tax_Id=395095 SubName: Full=Riboflavin bi...   448   e-124
tr|A2VJ49|A2VJ49_MYCTU Tax_Id=348776 SubName: Full=Riboflavin bi...   448   e-124
tr|C6DQF2|C6DQF2_MYCTK Tax_Id=478434 SubName: Full=Riboflavin bi...   446   e-123
tr|A1TC77|A1TC77_MYCVP Tax_Id=350058 SubName: Full=GTP cyclohydr...   388   e-106
tr|Q0RVJ1|Q0RVJ1_RHOSR Tax_Id=101510 SubName: Full=3,4-dihydroxy...   285   5e-75
tr|C6W8J2|C6W8J2_ACTMD Tax_Id=446462 SubName: Full=3,4-dihydroxy...   238   1e-60
tr|A8LE27|A8LE27_FRASN Tax_Id=298653 SubName: Full=3,4-dihydroxy...   236   3e-60
tr|C7MSL0|C7MSL0_SACVD Tax_Id=471857 SubName: Full=GTP cyclohydr...   236   4e-60
tr|C0WL37|C0WL37_9CORY Tax_Id=525260 (ribBA)SubName: Full=Bifunc...   233   4e-59
tr|A4FBK4|A4FBK4_SACEN Tax_Id=405948 (ribA)SubName: Full=3,4-dih...   231   1e-58
tr|Q2J849|Q2J849_FRASC Tax_Id=106370 SubName: Full=3,4-dihydroxy...   229   3e-58
tr|C0XSV8|C0XSV8_9CORY Tax_Id=525263 (ribBA)SubName: Full=Bifunc...   227   2e-57
tr|Q0RF94|Q0RF94_FRAAA Tax_Id=326424 (ribA)SubName: Full=Ribofla...   226   3e-57
tr|C2GHT6|C2GHT6_9CORY Tax_Id=548478 (ribBA)SubName: Full=3,4-di...   226   3e-57
tr|C0VVY7|C0VVY7_9CORY Tax_Id=548477 (ribBA)SubName: Full=3,4-di...   226   3e-57
tr|C4LIS4|C4LIS4_CORK4 Tax_Id=645127 SubName: Full=GTP cyclohydr...   226   3e-57
tr|Q6NH28|Q6NH28_CORDI Tax_Id=1717 (ribA)SubName: Full=Riboflavi...   226   4e-57
tr|B1VDP5|B1VDP5_CORU7 Tax_Id=504474 SubName: Full=GTP cyclohydr...   226   4e-57
tr|D0LCS6|D0LCS6_GORB4 Tax_Id=526226 SubName: Full=GTP cyclohydr...   225   8e-57
sp|Q5YTP3|RIBBA_NOCFA Tax_Id=37329 (ribBA)RecName: Full=Riboflav...   224   1e-56
tr|C2CMN9|C2CMN9_CORST Tax_Id=525268 (ribBA)SubName: Full=Bifunc...   224   1e-56
sp|C0ZZE5|RIBBA_RHOE4 Tax_Id=234621 (ribBA)RecName: Full=Ribofla...   223   2e-56
tr|C3JSV7|C3JSV7_RHOER Tax_Id=596309 SubName: Full=Riboflavin bi...   223   2e-56
sp|A0PPL6|RIBBA_MYCUA Tax_Id=362242 (ribBA)RecName: Full=Ribofla...   223   3e-56
tr|C2ATI3|C2ATI3_TSUPA Tax_Id=521096 SubName: Full=GTP cyclohydr...   223   3e-56
sp|P0A5V0|RIBBA_MYCTU Tax_Id=1773 (ribBA)RecName: Full=Riboflavi...   222   5e-56
sp|A5U2B7|RIBBA_MYCTA Tax_Id=419947 (ribBA)RecName: Full=Ribofla...   222   5e-56
sp|C1AN60|RIBBA_MYCBT Tax_Id=561275 (ribBA)RecName: Full=Ribofla...   222   5e-56
sp|A1KIK4|RIBBA_MYCBP Tax_Id=410289 (ribBA)RecName: Full=Ribofla...   222   5e-56
sp|P0A5V1|RIBBA_MYCBO Tax_Id=1765 (ribBA)RecName: Full=Riboflavi...   222   5e-56
tr|C6DTG8|C6DTG8_MYCTK Tax_Id=478434 SubName: Full=Riboflavin bi...   222   5e-56
tr|C0UA87|C0UA87_9ACTO Tax_Id=526225 SubName: Full=GTP cyclohydr...   222   5e-56
tr|A5WM98|A5WM98_MYCTF Tax_Id=336982 SubName: Full=Riboflavin bi...   222   5e-56
tr|A4KGX1|A4KGX1_MYCTU Tax_Id=395095 SubName: Full=Riboflavin bi...   222   5e-56
tr|A2VHU4|A2VHU4_MYCTU Tax_Id=348776 SubName: Full=Riboflavin bi...   222   5e-56
sp|Q0S0K2|RIBBA_RHOSR Tax_Id=101510 (ribBA)RecName: Full=Ribofla...   222   6e-56
sp|O24752|RIBBA_CORAM Tax_Id=1697 (ribBA)RecName: Full=Riboflavi...   221   8e-56
tr|C1B4K9|C1B4K9_RHOOB Tax_Id=632772 (ribA)SubName: Full=3,4-dih...   221   8e-56
tr|Q4JVI5|Q4JVI5_CORJK Tax_Id=306537 (ribA)SubName: Full=GTP cyc...   221   1e-55
sp|B2HP67|RIBBA_MYCMM Tax_Id=216594 (ribBA)RecName: Full=Ribofla...   220   2e-55
tr|C8NUG1|C8NUG1_9CORY Tax_Id=585529 (ribA)SubName: Full=3,4-dih...   220   2e-55

>tr|B2HE28|B2HE28_MYCMM Tax_Id=216594 (ribA1)SubName:
           Full=Riboflavin biosynthesis protein
           RibA1;[Mycobacterium marinum]
          Length = 365

 Score =  636 bits (1641), Expect = e-180
 Identities = 319/344 (92%), Positives = 319/344 (92%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD              PVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL
Sbjct: 1   MKTTDVRVRRAITAIAAGRPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTI           DFLRPGH
Sbjct: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIAALASAGSQAADFLRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE
Sbjct: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG
Sbjct: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC
Sbjct: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF
Sbjct: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344


>tr|Q5SDQ2|Q5SDQ2_MYCMR Tax_Id=1781 (melJ)SubName: Full=Putative
           cyclohydrolase;[Mycobacterium marinum]
          Length = 365

 Score =  636 bits (1641), Expect = e-180
 Identities = 319/344 (92%), Positives = 319/344 (92%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD              PVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL
Sbjct: 1   MKTTDVRVRRAITAIAAGRPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTI           DFLRPGH
Sbjct: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIAALASAGSQAADFLRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE
Sbjct: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG
Sbjct: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC
Sbjct: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF
Sbjct: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344


>tr|A0PS46|A0PS46_MYCUA Tax_Id=362242 (ribA1)SubName:
           Full=Riboflavin biosynthesis protein
           RibA1;[Mycobacterium ulcerans]
          Length = 365

 Score =  634 bits (1636), Expect = e-180
 Identities = 317/344 (92%), Positives = 319/344 (92%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD              PVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL
Sbjct: 1   MKTTDVRVRRAITAIAAGRPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTI           DFLRPGH
Sbjct: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIAALASAGSQAADFLRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE
Sbjct: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAV+IG
Sbjct: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVVIG 240

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYL+PPGPPRAC
Sbjct: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLQPPGPPRAC 300

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF
Sbjct: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344


>tr|Q7TZ92|Q7TZ92_MYCBO Tax_Id=1765 (ribA1)SubName: Full=Probable
           Riboflavin biosynthesis protein ribA1 (GTP
           cyclohydrolase II); EC=3.5.4.25;[Mycobacterium bovis]
          Length = 353

 Score =  448 bits (1152), Expect = e-124
 Identities = 237/344 (68%), Positives = 259/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWAG SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|Q7D7R0|Q7D7R0_MYCTU Tax_Id=1773 (ribA1)SubName:
           Full=3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
           cyclohydrolase II; EC=3.5.4.25; SubName: Full=Probable
           Riboflavin biosynthesis protein ribA1 (GTP
           cyclohydrolase II); EC=3.5.4.25;[Mycobacterium
           tuberculosis]
          Length = 353

 Score =  448 bits (1152), Expect = e-124
 Identities = 237/344 (68%), Positives = 259/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWAG SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|C1APL9|C1APL9_MYCBT Tax_Id=561275 (ribA1)SubName: Full=Putative
           riboflavin biosynthesis protein;
           EC=3.5.4.25;[Mycobacterium bovis]
          Length = 353

 Score =  448 bits (1152), Expect = e-124
 Identities = 237/344 (68%), Positives = 259/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWAG SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|A5U3V9|A5U3V9_MYCTA Tax_Id=419947 (ribA1)SubName:
           Full=3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
           cyclohydrolase II;[Mycobacterium tuberculosis]
          Length = 353

 Score =  448 bits (1152), Expect = e-124
 Identities = 237/344 (68%), Positives = 259/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWAG SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|A1KK05|A1KK05_MYCBP Tax_Id=410289 (ribA1)SubName: Full=Probable
           Riboflavin biosynthesis protein ribA1 (GTP
           cyclohydrolase II); EC=3.5.4.25;[Mycobacterium bovis]
          Length = 353

 Score =  448 bits (1152), Expect = e-124
 Identities = 237/344 (68%), Positives = 259/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWAG SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|A5WNR5|A5WNR5_MYCTF Tax_Id=336982 SubName: Full=Riboflavin
           biosynthesis protein ribA1 (GTP cyclohydrolase
           II);[Mycobacterium tuberculosis]
          Length = 353

 Score =  448 bits (1152), Expect = e-124
 Identities = 237/344 (68%), Positives = 259/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWAG SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|A4KI84|A4KI84_MYCTU Tax_Id=395095 SubName: Full=Riboflavin
           biosynthesis protein ribA1 (GTP cyclohydrolase
           II);[Mycobacterium tuberculosis str. Haarlem]
          Length = 353

 Score =  448 bits (1152), Expect = e-124
 Identities = 237/344 (68%), Positives = 259/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWAG SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|A2VJ49|A2VJ49_MYCTU Tax_Id=348776 SubName: Full=Riboflavin
           biosynthesis protein ribA1 (GTP cyclohydrolase
           II);[Mycobacterium tuberculosis C]
          Length = 353

 Score =  448 bits (1152), Expect = e-124
 Identities = 237/344 (68%), Positives = 259/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWAG SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWAGASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|C6DQF2|C6DQF2_MYCTK Tax_Id=478434 SubName: Full=Riboflavin
           biosynthesis protein ribA1;[Mycobacterium tuberculosis]
          Length = 353

 Score =  446 bits (1146), Expect = e-123
 Identities = 236/344 (68%), Positives = 258/344 (75%), Gaps = 4/344 (1%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVAL 60
           MKTTD               VV+T D    GYLVFAA+AAT  LVAF VRHT+GY+RVAL
Sbjct: 1   MKTTDVRVRRAITAMAGGHAVVLTGDPNGDGYLVFAAQAATPRLVAFAVRHTSGYLRVAL 60

Query: 61  PGAECARLNLPPMCHHNPTHRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGH 120
           PGAEC RL+LPPMC  + TH VSVDVR TGTGISA DRA TI           DF RPGH
Sbjct: 61  PGAECERLHLPPMCDRDTTHCVSVDVRGTGTGISASDRAWTIAALASATSVAADFQRPGH 120

Query: 121 VAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVE 180
           V P+ A+  GVL +  PAEAAVDLARLA  RPAAALCEIVS  NP  MAH AE VEFAVE
Sbjct: 121 VVPVQAQADGVLGRRGPAEAAVDLARLAERRPAAALCEIVSPDNPVQMAHHAESVEFAVE 180

Query: 181 HGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG 240
           HGLA+VSI EL+AYR+R EPQV+R T  TLPTWA  SRVIGFRD+      GEHLAVI+G
Sbjct: 181 HGLAMVSIGELVAYRRRIEPQVVRFTAATLPTWASASRVIGFRDVYDL---GEHLAVIVG 237

Query: 241 APDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRAC 300
           A  +GVPV LHVHIECLTGDVFGST CRCG ELNGAL+ MSAQGSGVVLYLRPPGP +AC
Sbjct: 238 AVGAGVPVPLHVHIECLTGDVFGSTACRCGEELNGALARMSAQGSGVVLYLRPPGPAQAC 297

Query: 301 GLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           GLFA   +   D M ETVTW+LRDLGVYAI+LSDD+PGFGLVMF
Sbjct: 298 GLFARG-DAATDVMPETVTWILRDLGVYAIRLSDDVPGFGLVMF 340


>tr|A1TC77|A1TC77_MYCVP Tax_Id=350058 SubName: Full=GTP
           cyclohydrolase II; EC=3.5.4.25;[Mycobacterium
           vanbaalenii]
          Length = 359

 Score =  388 bits (997), Expect = e-106
 Identities = 206/352 (58%), Positives = 244/352 (69%), Gaps = 11/352 (3%)

Query: 1   MKTTDXXXXXXXXXXXXXXPVVVTHDHAAQG--YLVFAAEAATSSLVAFTVRHTAGYVRV 58
           M+TTD              PVVVT D   +G  YLVFAA+AAT +++AFTVRHT+G VRV
Sbjct: 1   MRTTDLRVRRAIRAVAEGRPVVVTADTEREGAGYLVFAADAATPNILAFTVRHTSGLVRV 60

Query: 59  ALPGAECARLNLPPMCHHNP------THRVSVDVRATGTGISARDRARTIXXXXXXXXXX 112
           ALP +ECARL+LPPMC  +P        RV+VD    GTGISA DRARTI          
Sbjct: 61  ALPLSECARLDLPPMCSADPDGSHAAAQRVAVDAGGNGTGISATDRARTIAALASEHAQP 120

Query: 113 XDFLRPGHVAPLLAEPHGVLAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGA 172
            DF RPGHV P+ A   GVL      EAAVDLARL+G R AA LCEIVSR +P  +A G 
Sbjct: 121 GDFRRPGHVIPVQANADGVLGSPGAVEAAVDLARLSGRRQAAGLCEIVSRNHPATIACGT 180

Query: 173 ELVEFAVEHGLAVVSIAELLAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGG 232
           E VEFA+EHGLA VSI EL+AYR+RTE QV+RL ET LPT  G  RVIGFRD+   + G 
Sbjct: 181 EPVEFALEHGLATVSIGELVAYRRRTERQVVRLAETVLPTGCGTHRVIGFRDV---HGGA 237

Query: 233 EHLAVIIGAPDSGVPVALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           EHL ++IG+  SG PV LHVH+ECLTGDVFGST C CG EL+ A++ MSAQG GV++YLR
Sbjct: 238 EHLVLVIGSVGSGEPVPLHVHVECLTGDVFGSTVCHCGAELDSAVATMSAQGGGVIVYLR 297

Query: 293 PPGPPRACGLFASDEETPADFMSETVTWMLRDLGVYAIKLSDDMPGFGLVMF 344
           PPG  RACGL   D     D +S+TV W+LRDLGVY+++L+DD PG+GLVMF
Sbjct: 298 PPGSLRACGLPRPDHSPSPDLLSDTVAWILRDLGVYSLRLADDAPGYGLVMF 349


>tr|Q0RVJ1|Q0RVJ1_RHOSR Tax_Id=101510 SubName:
           Full=3,4-dihydroxy-2-butanone-4-phosphate synthase/ GTP
           cyclohydrolase II; EC=3.5.4.25;[Rhodococcus sp.]
          Length = 355

 Score =  285 bits (730), Expect = 5e-75
 Identities = 166/318 (52%), Positives = 200/318 (62%), Gaps = 16/318 (5%)

Query: 20  PVVVTH--DHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PVVV    D   +G L+FAA  AT+ LVAFTVRHT+G+V VALPG EC RL LP M H N
Sbjct: 31  PVVVIDAADREGEGDLIFAAALATTELVAFTVRHTSGFVCVALPGDECDRLGLPAMHHSN 90

Query: 78  P-----THRVSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVL 132
                  +R++VD+R TGTGISA  RA TI           DF+RPGHV PL+A P GVL
Sbjct: 91  DDRFDTAYRITVDMRGTGTGISAASRAATIAALASPDSLASDFVRPGHVVPLMARPGGVL 150

Query: 133 AKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELL 192
            +    EAAVDL RLAG   A ALCEIVS+  P  MA G EL  FA EH L ++SIA+L+
Sbjct: 151 DRPGLTEAAVDLTRLAGVPAAGALCEIVSQDRPVDMARGPELERFAKEHDLVLLSIADLI 210

Query: 193 AYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSG---VPVA 249
            YRQRTEPQV R   T+LPT  G  R +G+     A+ G EH+A+++  P  G     V 
Sbjct: 211 HYRQRTEPQVRRGAVTSLPTDFGRFRAVGYVG---AHDGAEHMALVVD-PTGGRQFEEVP 266

Query: 250 LHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRACGLFASD--E 307
           +HVH ECL+GDVF ST C C  EL  A+    A+G GVVLYLRPPG PRACG+FA++  E
Sbjct: 267 VHVHTECLSGDVFRSTACGCRQELEKAMFQFCAEGCGVVLYLRPPGGPRACGIFATERNE 326

Query: 308 ETPADFMSETVTWMLRDL 325
              +  M     W+L DL
Sbjct: 327 GVNSSAMQAVADWILADL 344


>tr|C6W8J2|C6W8J2_ACTMD Tax_Id=446462 SubName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           EC=3.5.4.25;[Actinosynnema mirum]
          Length = 417

 Score =  238 bits (606), Expect = 1e-60
 Identities = 139/281 (49%), Positives = 174/281 (61%), Gaps = 11/281 (3%)

Query: 20  PVVVT--HDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PV+V    D   +G L+FAAE AT  LVAF VRHT+GY+ V+L  A+C RL+LPPM H N
Sbjct: 19  PVIVVDDEDRENEGDLIFAAEKATPELVAFMVRHTSGYICVSLTEADCVRLDLPPMYHTN 78

Query: 78  PTHR-----VSVDVRATGT-GISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGV 131
              R     V+VD +  GT GISA DRARTI            F RPGHV PL A   GV
Sbjct: 79  QDERGTAYAVTVDAKQGGTTGISAADRARTIRLLADATATPAHFTRPGHVVPLRARDGGV 138

Query: 132 LAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAEL 191
           L +    EAAVDL+RLAG  P   LCEIVS+++   MA   EL  FA EH LA+++IA+L
Sbjct: 139 LRRTGHTEAAVDLSRLAGLAPVGVLCEIVSQKDEGDMAQREELEVFAAEHDLALITIADL 198

Query: 192 LAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALH 251
           +AYR+R E QV R+ E  +PT  G  R  G+        G EH+A++ G    G  V + 
Sbjct: 199 VAYRRRVEVQVQRVAEARIPTAHGVFRAYGY---DSKVDGIEHVALVCGEVGDGEEVLVR 255

Query: 252 VHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           VH ECLTGDV GS  C CG +L+ AL+A++A+G GVVLY+R
Sbjct: 256 VHSECLTGDVLGSLRCDCGPQLDAALAAVAAEGRGVVLYMR 296


>tr|A8LE27|A8LE27_FRASN Tax_Id=298653 SubName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           EC=3.5.4.25;[Frankia sp.]
          Length = 444

 Score =  236 bits (602), Expect = 3e-60
 Identities = 144/281 (51%), Positives = 175/281 (62%), Gaps = 13/281 (4%)

Query: 20  PVVVTHD--HAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PVVV  D     +G L+FAAEAAT  L+AF VRHTAG V V L  AE  RL+L  M   N
Sbjct: 18  PVVVVDDADRENEGDLIFAAEAATPELLAFMVRHTAGVVCVPLDPAEVDRLDLDQMVPQN 77

Query: 78  PTHR-----VSVDVRA-TGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGV 131
                    +SVD R+   TGISA DRARTI           D  RPGH+ PL A+  GV
Sbjct: 78  TDRMGTAFTISVDARSGVTTGISAADRARTIRLLADPATQPGDLTRPGHIFPLRAKEGGV 137

Query: 132 LAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAEL 191
           L +    EAAVDLARLAG RPA A+CEIV+      MA   EL  FA EHGLA++SIA+L
Sbjct: 138 LRRPGHTEAAVDLARLAGLRPAGAICEIVNEDGS--MARLPELTAFAREHGLALISIADL 195

Query: 192 LAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALH 251
           +AYR+RTE QV+R+ E  +PT  G+ R +G+R       G EH+A+I G    G  V + 
Sbjct: 196 IAYRRRTEKQVVRVAEARIPTRYGSFRAVGYRG---TLDGVEHIALIRGEVGDGENVLVR 252

Query: 252 VHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           VH ECLTGDVFGS  C CG +L+ AL A++A+G GVVLY+R
Sbjct: 253 VHSECLTGDVFGSQRCDCGNQLDAALRAVAAEGRGVVLYVR 293


>tr|C7MSL0|C7MSL0_SACVD Tax_Id=471857 SubName: Full=GTP
           cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate
           synthase;[Saccharomonospora viridis]
          Length = 438

 Score =  236 bits (601), Expect = 4e-60
 Identities = 138/281 (49%), Positives = 171/281 (60%), Gaps = 11/281 (3%)

Query: 20  PVVVT--HDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PVVV    D   +G L+FAAE AT  L+AF VR+T+GY+ VAL G +C RL+LPPM H N
Sbjct: 27  PVVVVDDEDRENEGDLIFAAEKATPELLAFMVRYTSGYICVALTGEDCDRLDLPPMYHSN 86

Query: 78  PTHR-----VSVDV-RATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGV 131
              R     V+VD     GTGISA DR  TI           D  RPGHV PL A+  GV
Sbjct: 87  QDRRGTAYTVTVDAAEGIGTGISATDRCHTIRLLADPNSKASDLTRPGHVVPLRAKDGGV 146

Query: 132 LAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAEL 191
           L +    EAAVDLAR+AG  PA  LCEIVS++N   MA   EL  FA +H L +++IA+L
Sbjct: 147 LRRPGHTEAAVDLARMAGLAPAGVLCEIVSQKNEGDMARRDELEVFAADHDLQLITIADL 206

Query: 192 LAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALH 251
           +AYR+R E QV R+ E  +P  AG  R IG+  L     G EH+A + G    G  + + 
Sbjct: 207 IAYRKRREKQVERVAEARIPLAAGTFRAIGYDSL---LDGIEHVAFVYGDIGDGEDILVR 263

Query: 252 VHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           VH ECLTGDVFGS  C CG +L  AL A++ +G GVVLY+R
Sbjct: 264 VHSECLTGDVFGSLRCDCGPQLQAALKAVADEGRGVVLYVR 304


>tr|C0WL37|C0WL37_9CORY Tax_Id=525260 (ribBA)SubName:
           Full=Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate
           synthase/GTP cyclohydrolase II protein;
           EC=3.5.4.25;[Corynebacterium accolens ATCC 49725]
          Length = 425

 Score =  233 bits (593), Expect = 4e-59
 Identities = 141/284 (49%), Positives = 169/284 (59%), Gaps = 15/284 (5%)

Query: 20  PVVVTHDHAAQ--GYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PV+V  D   +  G L+FAAE AT  LVAF VR+++GYV  +L   +C RL+LPPM   N
Sbjct: 25  PVIVMDDEGRENEGDLIFAAELATPELVAFMVRYSSGYVCASLLPEDCQRLDLPPMMAQN 84

Query: 78  PTHR-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVL 132
              R     V+VD     TGISA  RA TI           DF RPGHV PL A P GVL
Sbjct: 85  QDVRQTAYTVTVDAATGSTGISAASRAETIRRLADPSTRSSDFTRPGHVVPLRARPGGVL 144

Query: 133 AKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELL 192
            +    EAAVDLARLAG RPA  LCE+VS  +PT MA G EL  FA +HGLA++SIA+L+
Sbjct: 145 ERDGHTEAAVDLARLAGLRPAGVLCEVVSEEDPTDMARGPELRRFADKHGLALISIAQLI 204

Query: 193 AYRQRTEPQVIRLTETTLPTWAGNSRVIGFR-DLGPANPGGEHLAVIIGAPD---SGVPV 248
            +R+  E Q  R  ET LPT  G    IG+R DL     G EH+A+I G P        V
Sbjct: 205 EWRRHHEVQTQRAVETRLPTEYGEFTAIGYRHDL----DGQEHIALIAGDPTQLRGARDV 260

Query: 249 ALHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            + VH ECLTGDVFGS  C CG +L  +L  +   GSGVV+YLR
Sbjct: 261 VVRVHSECLTGDVFGSRRCDCGPQLQESLRKVQEAGSGVVIYLR 304


>tr|A4FBK4|A4FBK4_SACEN Tax_Id=405948 (ribA)SubName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           EC=3.5.4.25;[Saccharopolyspora erythraea]
          Length = 437

 Score =  231 bits (589), Expect = 1e-58
 Identities = 134/281 (47%), Positives = 171/281 (60%), Gaps = 11/281 (3%)

Query: 20  PVVVT--HDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PV+V    D   +G L+FAAE AT  +VAF VR+T+GY+ VAL G +C RL+LPPM H N
Sbjct: 36  PVIVVDDEDRENEGDLIFAAEMATPEMVAFMVRYTSGYICVALTGEDCDRLDLPPMYHWN 95

Query: 78  PTHR-----VSVDV-RATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGV 131
              +     V+VD      TGISA DRA T+           D  RPGHV PL A   GV
Sbjct: 96  QDRKGTAYTVTVDAAEGVSTGISASDRAHTLKVLAHADSSADDLNRPGHVVPLRARDGGV 155

Query: 132 LAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAEL 191
           L +    EAAVDL+RLAG RPA ALCEIVS+++   MA   EL  FA EH LA+++IA+L
Sbjct: 156 LRRPGHTEAAVDLSRLAGLRPAGALCEIVSQKSEGDMARRDELEVFADEHDLALITIADL 215

Query: 192 LAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALH 251
           +AYR+R E QV+R+ E  +PT  G  R +G+        G EHLA++ G    G  + + 
Sbjct: 216 IAYRRRFEQQVVRVAEARIPTAHGTFRTVGY---DSTLDGIEHLALVYGDIGDGEDILVR 272

Query: 252 VHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           VH ECLTGDV GS  C CG +L  A+  ++  G GVVLY+R
Sbjct: 273 VHSECLTGDVLGSLRCDCGPQLAAAMEKVAEAGRGVVLYMR 313


>tr|Q2J849|Q2J849_FRASC Tax_Id=106370 SubName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP
           cyclohydrolase II; EC=3.5.4.25; EC=4.1.2.-; Flags:
           Precursor;[Frankia sp.]
          Length = 506

 Score =  229 bits (585), Expect = 3e-58
 Identities = 136/278 (48%), Positives = 171/278 (61%), Gaps = 11/278 (3%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHNPTH 80
           VV   D   +G L+FAAEAAT  LVAF  R+T+G + V +  A+  RL L  M  HN   
Sbjct: 46  VVDDADRENEGDLIFAAEAATPELVAFMTRYTSGVICVPMDAADTDRLELDQMVPHNTER 105

Query: 81  R-----VSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
                 ++VD R    TGISA DRARTI           D  RPGH+ PL A+  GVL +
Sbjct: 106 MGTAFTITVDARDGVSTGISAADRARTIRLLADPRTTPGDLSRPGHIFPLRAKDGGVLRR 165

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLARLAG RPA A+CEIV+  +   MA    L EFA EHGL ++SIA+L+AY
Sbjct: 166 PGHTEAAVDLARLAGLRPAGAICEIVN--DDGTMARLPRLAEFAREHGLLLISIADLIAY 223

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALHVHI 254
           R+RTE QV+R+ E +LPT  G  R +GFR++     G EH+A+I G    G  V + VH 
Sbjct: 224 RRRTEKQVVRVAEASLPTRYGAFRAVGFRNI---LDGVEHIALIRGELGDGADVLVRVHS 280

Query: 255 ECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           ECLTGDVFGS  C CG +L+ AL  ++ +G GVVLY+R
Sbjct: 281 ECLTGDVFGSRRCDCGTQLDAALRIIATEGRGVVLYMR 318


>tr|C0XSV8|C0XSV8_9CORY Tax_Id=525263 (ribBA)SubName:
           Full=Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate
           synthase/GTP cyclohydrolase II protein;
           EC=3.5.4.25;[Corynebacterium lipophiloflavum DSM 44291]
          Length = 418

 Score =  227 bits (579), Expect = 2e-57
 Identities = 131/277 (47%), Positives = 164/277 (59%), Gaps = 8/277 (2%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHNPTH 80
           VV   D   +G L+FAAE AT  LVAF VRHT+GY+ VAL  A+  RL LPPM   N   
Sbjct: 25  VVDDEDRENEGDLIFAAELATPELVAFMVRHTSGYICVALENADADRLQLPPMVARNEDA 84

Query: 81  R-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAKC 135
           R     V+VD     TGISAR R  TI           DF RPGHV PL A   GVL + 
Sbjct: 85  RATAYTVTVDAATGTTGISARSRCETITRLADPARTAADFTRPGHVVPLRARAGGVLVRD 144

Query: 136 EPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAYR 195
              EA+VDLARLAG RPA  LCEIVS  +PT MA G EL  FA EHGL ++SI +L+ YR
Sbjct: 145 GHTEASVDLARLAGVRPAGVLCEIVSAEDPTDMARGPELRRFADEHGLVMISIQQLIDYR 204

Query: 196 QRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALHVHIE 255
           +  +  V R T+T LPT  G  +  G+R+      G EH+A+++G   +   V + VH E
Sbjct: 205 RHRDNFVTRCTQTRLPTEFGEFQAYGYRN---TIDGTEHVALVVGDVAAQPGVLVRVHSE 261

Query: 256 CLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           CLTGDVF S  C CG +L+ ++  +   G GV++Y+R
Sbjct: 262 CLTGDVFASRRCDCGPQLHESMRRIQEAGRGVIVYVR 298


>tr|Q0RF94|Q0RF94_FRAAA Tax_Id=326424 (ribA)SubName: Full=Riboflavin
           biosynthesis protein ribA; EC=3.5.4.25;[Frankia alni]
          Length = 516

 Score =  226 bits (577), Expect = 3e-57
 Identities = 134/278 (48%), Positives = 170/278 (61%), Gaps = 11/278 (3%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHNPTH 80
           VV   D   +G L+FAAEAAT  LVAF  R+T+G + V +   +  RL L  M  HN   
Sbjct: 87  VVDDADRENEGDLIFAAEAATPELVAFMTRYTSGVICVPMDAVDTDRLELDQMVPHNTER 146

Query: 81  R-----VSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
                 ++VD R    TGISA DRARTI           D  RPGH+ PL A+  GVL +
Sbjct: 147 MGTAFTITVDAREGVSTGISAADRARTIRLLADPDTVPGDLSRPGHIFPLRAKDGGVLRR 206

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLARLAG RPA  +CEIV+  +   MA   EL  FA +HGL ++SIA+L+AY
Sbjct: 207 PGHTEAAVDLARLAGLRPAGTICEIVN--DDGTMARLPELAAFARDHGLLLISIADLIAY 264

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALHVHI 254
           R+RTE QV+R+ E T+PT  G  R +GFR++     G EH+A+I G    G  V + VH 
Sbjct: 265 RRRTEKQVVRVAEATIPTSYGTFRAVGFRNV---LDGVEHIALIRGELGDGEDVLVRVHS 321

Query: 255 ECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           ECLTGDVFGS  C CG +L+ AL  ++A+G GVVLY+R
Sbjct: 322 ECLTGDVFGSRRCDCGTQLDAALRMIAAEGRGVVLYVR 359


>tr|C2GHT6|C2GHT6_9CORY Tax_Id=548478 (ribBA)SubName:
           Full=3,4-dihydroxy-2-butanone-4-phosphate synthase;
           EC=4.1.99.12;[Corynebacterium glucuronolyticum ATCC
           51866]
          Length = 431

 Score =  226 bits (577), Expect = 3e-57
 Identities = 146/344 (42%), Positives = 187/344 (54%), Gaps = 30/344 (8%)

Query: 20  PVVVT--HDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PVVV    D   +G ++FAAE AT  L+ F VR+++GYV   L GA+C RL LPPM  +N
Sbjct: 25  PVVVVDDEDRENEGDIIFAAEKATPELMGFLVRYSSGYVCAPLTGADCDRLQLPPMVQNN 84

Query: 78  PTHR-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVL 132
              R     V+VD     TGISA  R  T+           DF RPGHVAPL A   GVL
Sbjct: 85  QDVRGTAYTVTVDAATGSTGISAMSRCETVRRLASATSTPDDFTRPGHVAPLRAREGGVL 144

Query: 133 AKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELL 192
            +    EAA+DLARLAG RPA  LCE+VS  +PT MA   EL  FA  HGL ++SIA+L+
Sbjct: 145 VRAGHTEAAIDLARLAGLRPAGVLCEVVSEDDPTDMARLPELRRFADTHGLKLISIAQLI 204

Query: 193 AYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALHV 252
            +R+  E  V R+ ET LPT  G  +  G+  L     G EH+A++ G    G  + + V
Sbjct: 205 EWRRAHEKLVERVAETRLPTEYGQFKAYGYTSL---VDGVEHVALVAGEIGDGENILVRV 261

Query: 253 HIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRACGLFA-------S 305
           H ECLTGDVFGS  C CG +L+ AL  +  +G G++LY+R     R  GL A        
Sbjct: 262 HSECLTGDVFGSRRCDCGQQLHAALKKIQDEGRGILLYMR-GHEGRGIGLLAKLKAYQLQ 320

Query: 306 DEET-----------PADFMS-ETVTWMLRDLGVYAIKLSDDMP 337
           DE             PAD     T   +L DLGV +++L  + P
Sbjct: 321 DEGADTVDANLALGFPADAREYGTGAQILADLGVKSLRLITNNP 364


>tr|C0VVY7|C0VVY7_9CORY Tax_Id=548477 (ribBA)SubName:
           Full=3,4-dihydroxy-2-butanone-4-phosphate synthase;
           EC=4.1.99.12;[Corynebacterium glucuronolyticum ATCC
           51867]
          Length = 431

 Score =  226 bits (577), Expect = 3e-57
 Identities = 146/344 (42%), Positives = 187/344 (54%), Gaps = 30/344 (8%)

Query: 20  PVVVT--HDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PVVV    D   +G ++FAAE AT  L+ F VR+++GYV   L GA+C RL LPPM  +N
Sbjct: 25  PVVVVDDEDRENEGDIIFAAEKATPELMGFLVRYSSGYVCAPLTGADCDRLQLPPMVQNN 84

Query: 78  PTHR-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVL 132
              R     V+VD     TGISA  R  T+           DF RPGHVAPL A   GVL
Sbjct: 85  QDVRGTAYTVTVDAATGSTGISAMSRCETVRRLASATSTPDDFTRPGHVAPLRAREGGVL 144

Query: 133 AKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELL 192
            +    EAA+DLARLAG RPA  LCE+VS  +PT MA   EL  FA  HGL ++SIA+L+
Sbjct: 145 VRAGHTEAAIDLARLAGLRPAGVLCEVVSEDDPTDMARLPELRRFADTHGLKLISIAQLI 204

Query: 193 AYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALHV 252
            +R+  E  V R+ ET LPT  G  +  G+  L     G EH+A++ G    G  + + V
Sbjct: 205 EWRRAHEKLVERVAETRLPTEYGQFKAYGYTSL---VDGVEHVALVAGEIGDGENILVRV 261

Query: 253 HIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRACGLFA-------S 305
           H ECLTGDVFGS  C CG +L+ AL  +  +G G++LY+R     R  GL A        
Sbjct: 262 HSECLTGDVFGSRRCDCGQQLHAALKKIQDEGRGILLYMR-GHEGRGIGLLAKLKAYQLQ 320

Query: 306 DEET-----------PADFMS-ETVTWMLRDLGVYAIKLSDDMP 337
           DE             PAD     T   +L DLGV +++L  + P
Sbjct: 321 DEGADTVDANLALGFPADAREYGTGAQILADLGVKSLRLITNNP 364


>tr|C4LIS4|C4LIS4_CORK4 Tax_Id=645127 SubName: Full=GTP
           cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate
           synthase; EC=3.5.4.25;[Corynebacterium kroppenstedtii]
          Length = 461

 Score =  226 bits (576), Expect = 3e-57
 Identities = 132/283 (46%), Positives = 172/283 (60%), Gaps = 13/283 (4%)

Query: 20  PVVVT--HDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PV+V    D   +G ++ AA+  T++ +AF VR+++GYV V +   +  R +LPPM   N
Sbjct: 54  PVIVVDDEDRENEGDMIIAADRITATSLAFMVRYSSGYVCVGMTDDDADRCDLPPMVTRN 113

Query: 78  P-----THRVSVDVRATGT-GISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGV 131
                  + V+VD    GT GISA DRA TI           DF RPGHV PL A P GV
Sbjct: 114 QDKKSTAYTVTVDAAEGGTTGISATDRAHTIRLLASPDSGPADFTRPGHVVPLRARPGGV 173

Query: 132 LAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAEL 191
           L +    EAAVDLARLA   PA ALCE+VS  +PT MA G EL  FA EH L ++SI +L
Sbjct: 174 LVRAGHTEAAVDLARLAHLNPAGALCEVVSEDDPTTMARGPELRRFADEHSLTMISIDQL 233

Query: 192 LAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAP--DSGVPVA 249
           +AYR+ TE  V R+ ETTLPT  G    IG+R++     G EH+A+++G P  + G  V 
Sbjct: 234 IAYRRNTEQLVERVVETTLPTSYGRFTAIGYRNV---IDGLEHVALVVGDPSDNGGEDVL 290

Query: 250 LHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           + VH ECLTGDVFGS  C CG +L+ A+  +  +G GVVLY+R
Sbjct: 291 VRVHSECLTGDVFGSRRCDCGDQLHQAMEEVYKEGRGVVLYMR 333


>tr|Q6NH28|Q6NH28_CORDI Tax_Id=1717 (ribA)SubName: Full=Riboflavin
           biosynthesis protein RibA; EC=3.5.4.25;[Corynebacterium
           diphtheriae]
          Length = 412

 Score =  226 bits (575), Expect = 4e-57
 Identities = 133/282 (47%), Positives = 166/282 (58%), Gaps = 12/282 (4%)

Query: 20  PVVV--THDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PVVV  + D   +G L+FAA+ AT  LVAF VR+++GY+  +L   EC RL LPPM  HN
Sbjct: 18  PVVVVDSEDRENEGDLIFAADKATPELVAFMVRYSSGYICASLTSEECDRLQLPPMTSHN 77

Query: 78  PTHR-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVL 132
              R     V+VD     TGISA  RA T+           DF RPGHV PL A+  GVL
Sbjct: 78  EDARGTAYAVTVDANTGTTGISATSRADTLRKLADSQFGPQDFTRPGHVVPLRAKAGGVL 137

Query: 133 AKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELL 192
            +    EAAVDLAR+AG  PA  LCE+VS  +PT MA   EL  FA  H LA++SI +L+
Sbjct: 138 ERAGHTEAAVDLARMAGLNPAGVLCEVVSEDDPTDMARAPELRRFADRHDLALISIEQLI 197

Query: 193 AYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG--APDSGVPVAL 250
            +R+R E  V R   T LPT  G    +G+R +     G EH+A++ G    D G  V L
Sbjct: 198 EWRRRYELLVERAVSTQLPTEFGRFTAVGYRGI---VDGVEHIALVAGDITSDEGKDVLL 254

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDV GS  C CG +L  +L A+S +G GVV+YLR
Sbjct: 255 RVHSECLTGDVLGSRRCDCGPQLQASLRAISERGRGVVVYLR 296


>tr|B1VDP5|B1VDP5_CORU7 Tax_Id=504474 SubName: Full=GTP
           cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate
           synthase; EC=3.5.4.25;[Corynebacterium urealyticum]
          Length = 467

 Score =  226 bits (575), Expect = 4e-57
 Identities = 131/277 (47%), Positives = 161/277 (58%), Gaps = 8/277 (2%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHNPTH 80
           VV   D   +G L+FAA+ AT  LVAF VR+T+GY+ VA+       LNLPPM   N   
Sbjct: 73  VVDDEDRENEGDLIFAADLATPELVAFMVRYTSGYICVAMEDERADALNLPPMVARNEDA 132

Query: 81  R-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAKC 135
           R     V+VD     TGISAR R  TI            F RPGH+ PL A   GVLA+ 
Sbjct: 133 RSTAYTVTVDAATGSTGISARSRCETITRLADESFGPEAFTRPGHIVPLRARRGGVLARD 192

Query: 136 EPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAYR 195
              E++VDL+RLAG  P   LCEIVS  +PT MA G EL  FA EHGL +VSI +L+ YR
Sbjct: 193 GHTESSVDLSRLAGQAPVGVLCEIVSEDDPTDMARGPELRRFADEHGLRMVSIEQLIEYR 252

Query: 196 QRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALHVHIE 255
           + TE  V R TE  LPT  G  R +G+  L     G EH+A++ G       V + VH E
Sbjct: 253 RATEQTVERSTEARLPTTRGEFRAVGYTSL---IDGTEHVALVHGDVTGQKDVPVRVHSE 309

Query: 256 CLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           CLTGDVFGS  C CG +L+ A+ A+  +G GVV+YLR
Sbjct: 310 CLTGDVFGSLRCDCGEQLHAAMEAVQDEGHGVVIYLR 346


>tr|D0LCS6|D0LCS6_GORB4 Tax_Id=526226 SubName: Full=GTP
           cyclohydrolase II;[Gordonia bronchialis]
          Length = 442

 Score =  225 bits (573), Expect = 8e-57
 Identities = 131/280 (46%), Positives = 172/280 (61%), Gaps = 11/280 (3%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCH----- 75
           VV   D   +G L+FAAE AT  LVAF VR+T+GY+   L G  C RL LPPM       
Sbjct: 40  VVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCAPLDGDTCDRLGLPPMYSMNQDK 99

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 100 HGTAYTVTVDAREGIGTGISASDRATTMRLLADPASSAADFTRPGHVVPLRAKDGGVLRR 159

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLARLAG  PA  +CEIVS+++   MA   EL  FA EH LA++SIA+L+A+
Sbjct: 160 PGHTEAAVDLARLAGLTPAGVICEIVSQKDVGSMAQTDELRVFADEHELALISIADLIAW 219

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG--APDSGVPVALHV 252
           R+R E  V+R+ +  +PT  G+ R +G+  +       EH+A+++G  A   G  V + V
Sbjct: 220 RRRHEKHVVRVADARIPTRHGDFRAVGYSSV---YDEVEHVALVMGDIAAGDGHDVLVRV 276

Query: 253 HIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           H ECLTGDVFGS  C CG +L+ A+  ++A+G G+VLY+R
Sbjct: 277 HSECLTGDVFGSLRCDCGPQLDAAMEMVAAEGRGIVLYMR 316


>sp|Q5YTP3|RIBBA_NOCFA Tax_Id=37329 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Nocardia farcinica]
          Length = 414

 Score =  224 bits (571), Expect = 1e-56
 Identities = 128/278 (46%), Positives = 169/278 (60%), Gaps = 9/278 (3%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           VV   D   +G L+FAAE AT  LVAF +R+T+GY+ V L G +C RL LPPM       
Sbjct: 22  VVDDEDRENEGDLIFAAEKATPELVAFMIRYTSGYICVPLTGEDCDRLGLPPMYATNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + VSVD R    TGISA DRA T+           D  RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVSVDAREGITTGISAADRATTMRLLADADAKADDLTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG RPA  +CEIVS+++   MA   EL  FA +H LA++SIA+++A+
Sbjct: 142 PGHTEAAVDLARMAGLRPAGVICEIVSQKDEGHMARTEELRVFADDHDLALISIADMIAW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALHVHI 254
           R++ E QV+R+ E  +PT  G    +G++ +       EH+A++ G    G  V + VH 
Sbjct: 202 RRKHEKQVVRVAEARIPTAHGAFTAVGYQSI---YDDVEHVALVRGDIGDGEDVLVRVHS 258

Query: 255 ECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           ECLTGDVFGS  C CG +L+ AL  +  +G GVVLY+R
Sbjct: 259 ECLTGDVFGSLRCDCGPQLDAALEMVDQEGRGVVLYMR 296


>tr|C2CMN9|C2CMN9_CORST Tax_Id=525268 (ribBA)SubName:
           Full=Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate
           synthase/GTP cyclohydrolase II protein;
           EC=3.5.4.25;[Corynebacterium striatum ATCC 6940]
          Length = 420

 Score =  224 bits (571), Expect = 1e-56
 Identities = 148/352 (42%), Positives = 187/352 (53%), Gaps = 33/352 (9%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHNPTH 80
           VV   D   +G L+FAAE AT  LVAF VR+T+GY+   L   +CARLNLPPM   N   
Sbjct: 28  VVDNEDRENEGDLIFAAELATPELVAFMVRYTSGYICAPLMPEDCARLNLPPMIAVNEDV 87

Query: 81  R-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAKC 135
           R     V+VD     TGISA  RA TI           DF RPGHV PL A P GVL + 
Sbjct: 88  RHTAYTVTVDAATGSTGISAGSRAETIRRLADPTSEIGDFTRPGHVVPLAARPGGVLERD 147

Query: 136 EPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAYR 195
              EA++DLARLAG RPA  LCEIVS  +PT MA   EL  FA  HGL+++SI +L+ +R
Sbjct: 148 GHTEASIDLARLAGLRPAGVLCEIVSEEDPTDMARSPELRRFADTHGLSMISIEQLIEWR 207

Query: 196 QRTEPQVIRLTETTLPTWAGNSRVIGF-RDLGPANPGGEHLAVIIG---APDSGVPVALH 251
           +  E Q++R     LPT  G    IG+  D+  +    EH+A++ G   A      V + 
Sbjct: 208 RHHETQIVRSVSARLPTEHGVFTAIGYTHDVDKS----EHIALVAGDVEALKGAENVLVR 263

Query: 252 VHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRACGLFAS------ 305
           VH ECLTGDVFGS  C CG +LN +L A+   G GVV+YLR     R  GL         
Sbjct: 264 VHSECLTGDVFGSRRCDCGPQLNASLQAVQEAGQGVVVYLRGQ-EGRGIGLVNKLKAYHL 322

Query: 306 ------------DEETPADFMSETVT-WMLRDLGVYAIKLSDDMPGFGLVMF 344
                       ++  P D    +V   +LRDLG+ +  L  + P  G  +F
Sbjct: 323 QDKGLDTVEANLEQGLPEDAREYSVAGQILRDLGIVSANLMTNNPHKGDGLF 374


>sp|C0ZZE5|RIBBA_RHOE4 Tax_Id=234621 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Rhodococcus erythropolis]
          Length = 424

 Score =  223 bits (569), Expect = 2e-56
 Identities = 132/282 (46%), Positives = 171/282 (60%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           VV   D   +G L+FAAE AT  LVAF VR+T+GY+ V L G +C RL LPPM       
Sbjct: 22  VVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGDDCDRLGLPPMYATNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDAREGIGTGISASDRAATMRLLANPESGANDFTRPGHVVPLRAKEGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+A  RPA  +CEIVS+++   MA   EL  FA EH LA++SIA+L+A+
Sbjct: 142 PGHTEAAVDLARMADLRPAGVICEIVSQKDEGAMAQTDELRVFADEHNLALISIADLIAW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPD-SGVPVAL 250
           R++ E  V+R+ E  +PT  G    +G+  +       EH+A++   I  PD  G  V +
Sbjct: 202 RRKHEKHVLRIAEARIPTRHGEFTAVGYTSI---YDEVEHVALVRGDIAGPDGDGSDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL  ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMR 300


>tr|C3JSV7|C3JSV7_RHOER Tax_Id=596309 SubName: Full=Riboflavin
           biosynthesis protein ribBA; EC=3.5.4.25;
           EC=4.1.99.12;[Rhodococcus erythropolis SK121]
          Length = 424

 Score =  223 bits (569), Expect = 2e-56
 Identities = 132/282 (46%), Positives = 171/282 (60%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           VV   D   +G L+FAAE AT  LVAF VR+T+GY+ V L G +C RL LPPM       
Sbjct: 22  VVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGDDCDRLGLPPMYATNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDAREGIGTGISASDRAATMRLLANPESGANDFTRPGHVVPLRAKEGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+A  RPA  +CEIVS+++   MA   EL  FA EH LA++SIA+L+A+
Sbjct: 142 PGHTEAAVDLARMADLRPAGVICEIVSQKDEGAMAQTDELRVFADEHNLALISIADLIAW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPD-SGVPVAL 250
           R++ E  V+R+ E  +PT  G    +G+  +       EH+A++   I  PD  G  V +
Sbjct: 202 RRKHEKHVLRIAEARIPTRHGEFTAVGYTSI---YDEVEHVALVRGDIAGPDGDGSDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL  ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMR 300


>sp|A0PPL6|RIBBA_MYCUA Tax_Id=362242 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Mycobacterium ulcerans]
          Length = 425

 Score =  223 bits (568), Expect = 3e-56
 Identities = 131/282 (46%), Positives = 174/282 (61%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  LVAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGAVCDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD +   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDAKNGVGTGISASDRATTMRLLADPASVAEDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVSR++   MA   EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSRKDEGSMAQTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P+S G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRRGEFRAIGYTSI---YENVEHVALVRGEIAGPNSDGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ A++ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGSQLDAAMAMVAREGRGVVLYMR 300


>tr|C2ATI3|C2ATI3_TSUPA Tax_Id=521096 SubName: Full=GTP
           cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate
           synthase;[Tsukamurella paurometabola DSM 20162]
          Length = 415

 Score =  223 bits (568), Expect = 3e-56
 Identities = 127/280 (45%), Positives = 172/280 (61%), Gaps = 11/280 (3%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           VV   D   +G L+FAAE AT  LVAF VR+T+GY+ V L GA C +L LPPM       
Sbjct: 22  VVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGATCDKLGLPPMYATNQDK 81

Query: 76  HNPTHRVSVDVRA-TGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD +A  GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDAKAGVGTGISAADRATTMLKLADPDSTVDDFTRPGHVVPLRAKEGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLA +AG  PA  +CEIVS ++P  MA   EL  FA +H LA++SIA+L+A+
Sbjct: 142 PGHTEAAVDLATMAGLAPAGVICEIVSEKDPGGMAQTDELRVFADDHDLALISIADLIAW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG--APDSGVPVALHV 252
           R++ E  V+++    +PT  G+ + +G+  +   +   EH+A++ G    D G  V + V
Sbjct: 202 RRKHEKHVVQVASARIPTAHGDFQAVGYTSI---HDDVEHVALVKGDITADGGADVLVRV 258

Query: 253 HIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           H ECLTGDVFGS  C CG +L+ A+  ++ +G GVVLY+R
Sbjct: 259 HSECLTGDVFGSLRCDCGPQLDAAMEMVAQEGRGVVLYMR 298


>sp|P0A5V0|RIBBA_MYCTU Tax_Id=1773 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Mycobacterium tuberculosis]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>sp|A5U2B7|RIBBA_MYCTA Tax_Id=419947 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Mycobacterium tuberculosis]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>sp|C1AN60|RIBBA_MYCBT Tax_Id=561275 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Mycobacterium bovis]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>sp|A1KIK4|RIBBA_MYCBP Tax_Id=410289 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Mycobacterium bovis]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>sp|P0A5V1|RIBBA_MYCBO Tax_Id=1765 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Mycobacterium bovis]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>tr|C6DTG8|C6DTG8_MYCTK Tax_Id=478434 SubName: Full=Riboflavin
           biosynthesis protein ribA2;[Mycobacterium tuberculosis]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>tr|C0UA87|C0UA87_9ACTO Tax_Id=526225 SubName: Full=GTP
           cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate
           synthase;[Geodermatophilus obscurus DSM 43160]
          Length = 435

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/281 (46%), Positives = 168/281 (59%), Gaps = 11/281 (3%)

Query: 20  PVVVT--HDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHN 77
           PVVV    D   +G L+FA+E AT  LVAF VR+T+GY+ VA+   +  RL+LPPM   N
Sbjct: 22  PVVVMDDEDRENEGDLIFASELATPELVAFMVRYTSGYICVAVSEEDADRLDLPPMFRVN 81

Query: 78  PTHR-----VSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGV 131
              R     V+VD R    TGISA DRA TI           D  RPGH+ PL A   GV
Sbjct: 82  QDRRGTAYTVTVDAREGVTTGISAADRAHTIRLLASPETDSTDLARPGHIVPLRARDGGV 141

Query: 132 LAKCEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAEL 191
           L +    EAAVDLA LAG RP+  LCE+VS ++P  MA G EL  FA EH L ++SIA+L
Sbjct: 142 LRRPGHTEAAVDLAVLAGLRPSGTLCEVVSEKDPVGMARGDELRVFADEHDLCLISIADL 201

Query: 192 LAYRQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPDSGVPVALH 251
           +AYR+R +  V R+ E T+P   G    +G+R    +    EH+A + G    G  V + 
Sbjct: 202 IAYRKRFDKLVERVAEATVPLAPGTFTAVGYRS---SYDEREHVAFVYGNVGDGEDVLVR 258

Query: 252 VHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           VH ECLTGDVFGS  C CG +L  AL+A++ +G G+VLY+R
Sbjct: 259 VHSECLTGDVFGSLRCDCGPQLQAALAAVAQEGRGIVLYIR 299


>tr|A5WM98|A5WM98_MYCTF Tax_Id=336982 SubName: Full=Riboflavin
           biosynthesis protein ribA2: GTP cyclohydrolase II +
           3,4-dihydroxy-2-butanone 4-phosphate
           synthase;[Mycobacterium tuberculosis]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>tr|A4KGX1|A4KGX1_MYCTU Tax_Id=395095 SubName: Full=Riboflavin
           biosynthesis protein ribA2 : GTP cyclohydrolase II +
           3,4-dihydroxy-2-butanone 4-phosphate
           synthase;[Mycobacterium tuberculosis str. Haarlem]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>tr|A2VHU4|A2VHU4_MYCTU Tax_Id=348776 SubName: Full=Riboflavin
           biosynthesis protein ribA2 : GTP cyclohydrolase II +
           3,4-dihydroxy-2-butanone 4-phosphate
           synthase;[Mycobacterium tuberculosis C]
          Length = 425

 Score =  222 bits (566), Expect = 5e-56
 Identities = 131/282 (46%), Positives = 175/282 (62%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  +VAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MAH  EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P++ G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNADGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL+ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMR 300


>sp|Q0S0K2|RIBBA_RHOSR Tax_Id=101510 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Rhodococcus sp.]
          Length = 417

 Score =  222 bits (565), Expect = 6e-56
 Identities = 132/282 (46%), Positives = 171/282 (60%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           VV   D   +G L+FAAE AT  LVAF VR+T+GY+ V L GA+C RL LPPM       
Sbjct: 22  VVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGADCDRLGLPPMYATNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDAREGIGTGISASDRAATMRLLADPSSGAQDFTRPGHVVPLRAKEGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+A  RPA  +CEIVS+++   MA   EL  FA +H LA++SIA+L+A+
Sbjct: 142 PGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAQTDELRVFADDHNLALISIADLIAW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG---APD-SGVPVAL 250
           R++ E  V R+    +PT  G    +G+R +       EH+A++ G    PD  G  V +
Sbjct: 202 RRKHEKHVERVASARIPTRHGEFTAVGYRSI---YDDVEHVALVRGDLPGPDGDGSDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL  ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMR 300


>sp|O24752|RIBBA_CORAM Tax_Id=1697 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Corynebacterium
           ammoniagenes]
          Length = 423

 Score =  221 bits (564), Expect = 8e-56
 Identities = 142/347 (40%), Positives = 185/347 (53%), Gaps = 31/347 (8%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHNPTH 80
           VV   D   +G L+FAAE AT  LVAF VR+++GY+ V L   +C RLNLPPM   N   
Sbjct: 29  VVDNEDRENEGDLIFAAELATPELVAFMVRYSSGYICVPLLPEDCKRLNLPPMMGRNEDV 88

Query: 81  R-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAKC 135
           R     V+VD     TGISA  RA T+           DF RPGHV PL A P+GVL + 
Sbjct: 89  RGTAYTVTVDANTGTTGISATSRAETMLRLADPMSVVDDFTRPGHVVPLAARPNGVLERD 148

Query: 136 EPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAYR 195
              EAA+DLARLAG RPA  LCEIVS  +PT MA   EL  F+ EH L ++SI +L+ +R
Sbjct: 149 GHTEAAIDLARLAGLRPAGVLCEIVSEEDPTTMARSEELRRFSDEHDLKMISIEQLIEWR 208

Query: 196 QRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIGAPD---SGVPVALHV 252
           +  E QV R  ET LPT  G+   +G++       G EH+A+I G  +       V + V
Sbjct: 209 RHNETQVRRTVETQLPTDFGSFTALGYKH---EIDGQEHVALIAGGVEELNGAEDVFVRV 265

Query: 253 HIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLRPPGPPRACGLFAS------- 305
           H ECLTGDVF S  C CG +L+ ++  +   G G+++YLR     R  GL A        
Sbjct: 266 HSECLTGDVFHSRRCDCGQQLHQSMEIIQEAGQGIIIYLR-GHEGRGIGLLAKLKAYSLQ 324

Query: 306 -----------DEETPADFMSETVT-WMLRDLGVYAIKLSDDMPGFG 340
                      ++  P D    +V   +LRDLG+ +  L  + P  G
Sbjct: 325 DSGLDTVDANLEQGLPEDAREYSVAGQILRDLGIKSANLLTNNPHKG 371


>tr|C1B4K9|C1B4K9_RHOOB Tax_Id=632772 (ribA)SubName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
           cyclohydrolase II; EC=3.5.4.25;[Rhodococcus opacus]
          Length = 417

 Score =  221 bits (564), Expect = 8e-56
 Identities = 132/282 (46%), Positives = 171/282 (60%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           VV   D   +G L+FAAE AT  LVAF VR+T+GY+ V L GA+C RL LPPM       
Sbjct: 22  VVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGADCDRLGLPPMYATNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD R   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDAREGIGTGISASDRAATMRLLADPSSGAQDFTRPGHVVPLRAKEGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+A  RPA  +CEIVS+++   MA   EL  FA +H LA++SIA+L+A+
Sbjct: 142 PGHTEAAVDLARMADLRPAGVICEIVSQKDEGHMAQTDELRVFADDHDLALISIADLIAW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG---APD-SGVPVAL 250
           R++ E  V R+    +PT  G    +G+R +       EH+A++ G    PD  G  V +
Sbjct: 202 RRKHEKHVERVASARIPTRHGEFTAVGYRSI---YDDVEHVALVRGDLPGPDGDGSDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ AL  ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSLRCDCGPQLDAALDMVAQEGRGVVLYMR 300


>tr|Q4JVI5|Q4JVI5_CORJK Tax_Id=306537 (ribA)SubName: Full=GTP
           cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate
           synthase; EC=3.5.4.25;[Corynebacterium jeikeium]
          Length = 420

 Score =  221 bits (562), Expect = 1e-55
 Identities = 135/283 (47%), Positives = 167/283 (59%), Gaps = 14/283 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHNPTH 80
           VV   D   +G L+FAAE AT  L+AF VRH++GYV V +  A+C RL LPPM   N   
Sbjct: 32  VVDDEDRENEGDLIFAAELATPELMAFMVRHSSGYVCVGMDSADCDRLGLPPMVARNEDV 91

Query: 81  R-----VSVDV-RATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           R     V+VD      TGISA DRART+            F RPGHV PL A+  GVL +
Sbjct: 92  RGTAYTVTVDAAEGVDTGISATDRARTVRLLADPTSTVATFNRPGHVVPLRAKRGGVLVR 151

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR A   PA ALCEIVS+ +PT MA   EL  FA EH LA++SI +L  +
Sbjct: 152 QGHTEAAVDLARAANLAPAGALCEIVSKEDPTTMARLPELRRFADEHDLALISIEQLQDW 211

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG-----APDSGVPVA 249
           R+     + R  ET LPT  GN R IG+ ++     G EH+A++ G     +  S  PV 
Sbjct: 212 RRHHTQTLERAVETRLPTVHGNFRAIGYVNI---IDGTEHVALVKGDVSAVSTGSEEPVP 268

Query: 250 LHVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           + VH ECLTGDVFGS  C CG +L+ AL  + A+G GVV+YLR
Sbjct: 269 VRVHSECLTGDVFGSRRCDCGDQLSAALDYIEAKGRGVVIYLR 311


>sp|B2HP67|RIBBA_MYCMM Tax_Id=216594 (ribBA)RecName: Full=Riboflavin
           biosynthesis protein ribBA; Includes: RecName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase;
           Short=DHBP synthase; EC=4.1.99.12; Includes: RecName:
           Full=GTP cyclohydrolase-2; EC=3.5.4.25; AltName:
           Full=GTP cyclohydrolase II;[Mycobacterium marinum]
          Length = 425

 Score =  220 bits (560), Expect = 2e-55
 Identities = 130/282 (46%), Positives = 174/282 (61%), Gaps = 13/282 (4%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMC-----H 75
           V+   D   +G L+FAAE AT  LVAF VR+T+GY+ V L GA C RL L PM       
Sbjct: 22  VIDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYLCVPLDGAVCDRLGLLPMYAVNQDK 81

Query: 76  HNPTHRVSVDVR-ATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAK 134
           H   + V+VD +   GTGISA DRA T+           DF RPGHV PL A+  GVL +
Sbjct: 82  HGTAYTVTVDAKNGVGTGISASDRATTMRLLADPASVAEDFTRPGHVVPLRAKDGGVLRR 141

Query: 135 CEPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAY 194
               EAAVDLAR+AG +PA A+CEIVS+++   MA   EL  FA EHGLA+++IA+L+ +
Sbjct: 142 PGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFADEHGLALITIADLIEW 201

Query: 195 RQRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVI---IGAPDS-GVPVAL 250
           R++ E  + R+ E  +PT  G  R IG+  +       EH+A++   I  P+S G  V +
Sbjct: 202 RRKHEKHIERVAEARIPTRHGEFRAIGYTSI---YEDVEHVALVRGEIAGPNSDGDDVLV 258

Query: 251 HVHIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
            VH ECLTGDVFGS  C CG +L+ A++ ++ +G GVVLY+R
Sbjct: 259 RVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGVVLYMR 300


>tr|C8NUG1|C8NUG1_9CORY Tax_Id=585529 (ribA)SubName:
           Full=3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP
           cyclohydrolase II; EC=3.5.4.25;[Corynebacterium
           genitalium ATCC 33030]
          Length = 418

 Score =  220 bits (560), Expect = 2e-55
 Identities = 130/280 (46%), Positives = 167/280 (59%), Gaps = 11/280 (3%)

Query: 21  VVVTHDHAAQGYLVFAAEAATSSLVAFTVRHTAGYVRVALPGAECARLNLPPMCHHNPTH 80
           VV   D   +G L+FAA+ AT  LVAF VR+++GY+ V++  +  + LNLPPM   N   
Sbjct: 25  VVDDEDRENEGDLIFAADHATPELVAFMVRYSSGYICVSMEDSRASELNLPPMVAQNEDA 84

Query: 81  R-----VSVDVRATGTGISARDRARTIXXXXXXXXXXXDFLRPGHVAPLLAEPHGVLAKC 135
           R     V+VD     TGISAR RA TI            F RPGH+ PL A   GVLA+ 
Sbjct: 85  RGTAYAVTVDAATGTTGISARSRAETIRRLADPNCGPEAFTRPGHIVPLRARAGGVLARD 144

Query: 136 EPAEAAVDLARLAGHRPAAALCEIVSRRNPTLMAHGAELVEFAVEHGLAVVSIAELLAYR 195
              EAAVDL+R AG  P   LCEIVS  +PT MA G EL  FA EHGL ++SIA+L+ YR
Sbjct: 145 GHTEAAVDLSRTAGCAPVGVLCEIVSEDDPTDMARGPELRRFADEHGLPMISIAQLIKYR 204

Query: 196 QRTEPQVIRLTETTLPTWAGNSRVIGFRDLGPANPGGEHLAVIIG-APDSG--VPVALHV 252
           +RTEP V R   TTLPT  G     G+R L     G EH+A+++G   ++G    V + V
Sbjct: 205 RRTEPMVERAATTTLPTDYGVFTAYGYRAL---VDGTEHVALVVGDVTEAGGDDEVLVRV 261

Query: 253 HIECLTGDVFGSTGCRCGGELNGALSAMSAQGSGVVLYLR 292
           H ECLTGD F ST C CG +L+ ++  + A G GV++Y+R
Sbjct: 262 HSECLTGDAFSSTRCDCGPQLHESMRRIQAAGRGVIVYVR 301


  Database: Amellifera_nr
    Posted date:  Feb 5, 2010  5:10 AM
  Number of letters in database: 3,846,993,858
  Number of sequences in database:  11,275,203
  
Lambda     K      H
   0.321    0.136    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 11275203
Number of Hits to DB: 2,497,555,296
Number of extensions: 102837367
Number of successful extensions: 229006
Number of sequences better than 10.0: 2908
Number of HSP's gapped: 225385
Number of HSP's successfully gapped: 2908
Length of query: 365
Length of database: 3,846,993,858
Length adjustment: 139
Effective length of query: 226
Effective length of database: 2,279,740,641
Effective search space: 515221384866
Effective search space used: 515221384866
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 81 (35.8 bits)