BLASTP 2.2.16 [Mar-25-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= MMAR_3198 (521 letters) Database: Amellifera_nr; Agambiae_nr; Cfamiliaris_nr; Cbriggsae_nr; Celegans_nr; swiss_varsplic_nr; Dmelanogaster_nr; Drerio_nr; trembl_nr; Ggallus_nr; Hsapiens_nr; Mmusculus_nr; Ptroglodytes_nr; Rnorvegicus_nr; Tnigroviridis_nr; swiss_nr; wormpep_nr; yeastpep_nr; Aaegypti_nr; Btaurus_nr; Cintestinalis_nr; Mdomestica_nr; Mmulatta_nr; Scerevisiae_nr; Xtropicalis_nr; Csavignyi_nr; Dnovemcinctus_nr; Etelfairi_nr; Gaculeatus_nr; Lafricana_nr; Ocuniculus_nr; Trubripes_nr; Pberghei_nr; Pchabaudi_nr; Pfalciparum_nr; Pvivax_nr; Pyoelii_nr; Tgondii_nr; Pknowlesi_nr; Cporcellus_nr; Eeuropaeus_nr; Fcatus_nr; Mlucifugus_nr; Mmurinus_nr; Oanatinus_nr; Ogarnettii_nr; Olatipes_nr; Oprinceps_nr; Saraneus_nr; Stridecemlineatus_nr; Tbelangeri_nr; Ecaballus_nr; Ppygmaeus_nr 11,275,203 sequences; 3,846,993,858 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value tr|B2HGS1|B2HGS1_MYCMM Tax_Id=216594 (murE)SubName: Full=UDP-N-a... 911 0.0 tr|A0PTJ2|A0PTJ2_MYCUA Tax_Id=362242 (murE)SubName: Full=UDP-N-a... 906 0.0 sp|P65477|MURE_MYCTU Tax_Id=1773 (murE)RecName: Full=UDP-N-acety... 694 0.0 sp|P65478|MURE_MYCBO Tax_Id=1765 (murE)RecName: Full=UDP-N-acety... 694 0.0 tr|C6DPQ0|C6DPQ0_MYCTK Tax_Id=478434 SubName: Full=UDP-N-acetylm... 694 0.0 tr|C1AQ74|C1AQ74_MYCBT Tax_Id=561275 (murE)SubName: Full=UDP-N-a... 694 0.0 tr|A5U4I5|A5U4I5_MYCTA Tax_Id=419947 (murE)SubName: Full=UDP-N-a... 694 0.0 tr|A1KKK1|A1KKK1_MYCBP Tax_Id=410289 (murE)SubName: Full=Probabl... 694 0.0 tr|A5WPD0|A5WPD0_MYCTF Tax_Id=336982 SubName: Full=UDP-N-acetylm... 694 0.0 tr|A2VJQ4|A2VJQ4_MYCTU Tax_Id=348776 SubName: Full=UDP-N-acetylm... 694 0.0 sp|A0QF47|MURE_MYCA1 Tax_Id=243243 (murE)RecName: Full=UDP-N-ace... 679 0.0 sp|Q73YQ3|MURE_MYCPA Tax_Id=1770 (murE)RecName: Full=UDP-N-acety... 676 0.0 sp|O69557|MURE_MYCLE Tax_Id=1769 (murE)RecName: Full=UDP-N-acety... 652 0.0 tr|B8ZQP5|B8ZQP5_MYCLB Tax_Id=561304 (murE)SubName: Full=UDP-N-a... 652 0.0 tr|A3Q1M3|A3Q1M3_MYCSJ Tax_Id=164757 SubName: Full=UDP-N-acetylm... 595 e-168 tr|Q1B6W6|Q1B6W6_MYCSS Tax_Id=164756 SubName: Full=UDP-N-acetylm... 595 e-168 tr|A1UI59|A1UI59_MYCSK Tax_Id=189918 SubName: Full=UDP-N-acetylm... 595 e-168 tr|A0R021|A0R021_MYCS2 Tax_Id=246196 SubName: Full=UDP-N-acetylm... 581 e-164 tr|A1TAX3|A1TAX3_MYCVP Tax_Id=350058 SubName: Full=UDP-N-acetylm... 573 e-161 tr|A4TBF0|A4TBF0_MYCGI Tax_Id=350054 SubName: Full=UDP-N-acetylm... 566 e-159 tr|B1MP32|B1MP32_MYCA9 Tax_Id=561007 SubName: Full=UDP-N-acetylm... 480 e-133 tr|Q5YYY4|Q5YYY4_NOCFA Tax_Id=37329 (murE)SubName: Full=Putative... 448 e-124 tr|C2ATS6|C2ATS6_TSUPA Tax_Id=521096 SubName: Full=UDP-N-acetylm... 440 e-121 tr|D0LAT6|D0LAT6_GORB4 Tax_Id=526226 SubName: Full=UDP-N-acetylm... 440 e-121 tr|C1AU60|C1AU60_RHOOB Tax_Id=632772 (murE)SubName: Full=UDP-N-a... 421 e-116 tr|C1A0Y0|C1A0Y0_RHOE4 Tax_Id=234621 (murE)SubName: Full=UDP-N-a... 421 e-115 tr|Q0SHR6|Q0SHR6_RHOSR Tax_Id=101510 (murE1)SubName: Full=UDP-N-... 419 e-115 tr|C3JJ53|C3JJ53_RHOER Tax_Id=596309 SubName: Full=UDP-N-acetylm... 418 e-114 tr|A4FLW5|A4FLW5_SACEN Tax_Id=405948 (murE)SubName: Full=UDP-N-a... 402 e-110 tr|C7MV98|C7MV98_SACVD Tax_Id=471857 SubName: Full=UDP-N-acetylm... 401 e-109 tr|C6WDE7|C6WDE7_ACTMD Tax_Id=446462 SubName: Full=UDP-N-acetylm... 400 e-109 tr|C5VD82|C5VD82_9CORY Tax_Id=553207 SubName: Full=UDP-N-acetylm... 394 e-107 tr|C0E4M8|C0E4M8_9CORY Tax_Id=566549 SubName: Full=Putative unch... 392 e-107 tr|A8KZA6|A8KZA6_FRASN Tax_Id=298653 SubName: Full=UDP-N-acetylm... 391 e-106 tr|C0XS01|C0XS01_9CORY Tax_Id=525263 (murE)SubName: Full=UDP-N-a... 384 e-104 sp|Q8NNN0|MURE_CORGL Tax_Id=1718 (murE)RecName: Full=UDP-N-acety... 382 e-104 tr|A4QFM8|A4QFM8_CORGB Tax_Id=340322 SubName: Full=Putative unch... 382 e-104 tr|C8XGZ1|C8XGZ1_NAKMY Tax_Id=479431 SubName: Full=UDP-N-acetylm... 375 e-102 tr|C3PHG1|C3PHG1_CORA7 Tax_Id=548476 (murE)SubName: Full=UDP-N-a... 370 e-100 tr|C4LI45|C4LI45_CORK4 Tax_Id=645127 SubName: Full=UDP-N-acetylm... 365 6e-99 tr|C8NTK7|C8NTK7_9CORY Tax_Id=585529 (murE)SubName: Full=UDP-N-a... 365 1e-98 tr|B5I4K7|B5I4K7_9ACTO Tax_Id=463191 SubName: Full=UDP-N-acetylm... 362 9e-98 tr|Q6NGC3|Q6NGC3_CORDI Tax_Id=1717 (murE)SubName: Full=UDP-N-ace... 360 2e-97 tr|A0LTL8|A0LTL8_ACIC1 Tax_Id=351607 SubName: Full=UDP-N-acetylm... 359 4e-97 sp|Q8FNT5|MURE_COREF Tax_Id=152794 (murE)RecName: Full=UDP-N-ace... 358 1e-96 tr|C8NQ17|C8NQ17_COREF Tax_Id=196164 (murE)SubName: Full=UDP-N-a... 358 1e-96 tr|D1A7V1|D1A7V1_THECU Tax_Id=471852 SubName: Full=UDP-N-acetylm... 358 1e-96 tr|B1VHC9|B1VHC9_CORU7 Tax_Id=504474 SubName: Full=UDP-N-acetylm... 357 2e-96 tr|C2BNI4|C2BNI4_9CORY Tax_Id=525264 (murE)SubName: Full=UDP-N-a... 357 3e-96 tr|A1SL85|A1SL85_NOCSJ Tax_Id=196162 SubName: Full=UDP-N-acetylm... 355 8e-96 >tr|B2HGS1|B2HGS1_MYCMM Tax_Id=216594 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase MurE;[Mycobacterium marinum] Length = 521 Score = 911 bits (2355), Expect = 0.0 Identities = 473/521 (90%), Positives = 474/521 (90%) Query: 1 VSEVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLF 60 +SEVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLF Sbjct: 1 MSEVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLF 60 Query: 61 AALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEA 120 AALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEA Sbjct: 61 AALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEA 120 Query: 121 AALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTL 180 AALVYGHPSDRL E TIGIRIDGADIPSTL Sbjct: 121 AALVYGHPSDRLTVVGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRIDGADIPSTL 180 Query: 181 TTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPT 240 TTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPT Sbjct: 181 TTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPT 240 Query: 241 MADYFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVA 300 MADYFEAKALLFDPASALRGHSVVVCI ITVSATGQPAHWRATDVA Sbjct: 241 MADYFEAKALLFDPASALRGHSVVVCIDDEAGRAMADRAGAAITVSATGQPAHWRATDVA 300 Query: 301 PVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRV 360 PVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRV Sbjct: 301 PVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRV 360 Query: 361 PGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGR 420 PGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGR Sbjct: 361 PGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGR 420 Query: 421 IAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWART 480 IAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWART Sbjct: 421 IAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWART 480 Query: 481 GDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALESCT 521 GDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALESCT Sbjct: 481 GDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALESCT 521 >tr|A0PTJ2|A0PTJ2_MYCUA Tax_Id=362242 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase MurE;[Mycobacterium ulcerans] Length = 559 Score = 906 bits (2341), Expect = 0.0 Identities = 470/521 (90%), Positives = 471/521 (90%) Query: 1 VSEVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLF 60 VSEVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLF Sbjct: 39 VSEVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLF 98 Query: 61 AALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEA 120 AALAGSATHGARH ADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEA Sbjct: 99 AALAGSATHGARHTADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEA 158 Query: 121 AALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTL 180 AALVYGHPSDRL E TIGIRIDGADIPSTL Sbjct: 159 AALVYGHPSDRLTVVGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRIDGADIPSTL 218 Query: 181 TTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPT 240 TTPEAP LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPT Sbjct: 219 TTPEAPTLQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPT 278 Query: 241 MADYFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVA 300 MADYFEAKALLFDPASALRGHSVVVCI ITVSATGQPAHWRATDVA Sbjct: 279 MADYFEAKALLFDPASALRGHSVVVCIDDEAGRAMADRAGVAITVSATGQPAHWRATDVA 338 Query: 301 PVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRV 360 PVGAGGQEFTALDPAGVGHRVRIG PGHYNV+NCLLALAILDAVGVSPEQAAPGLRETRV Sbjct: 339 PVGAGGQEFTALDPAGVGHRVRIGSPGHYNVSNCLLALAILDAVGVSPEQAAPGLRETRV 398 Query: 361 PGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGR 420 PGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGR Sbjct: 399 PGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGR 458 Query: 421 IAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWART 480 IAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWART Sbjct: 459 IAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWART 518 Query: 481 GDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALESCT 521 GDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALESCT Sbjct: 519 GDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALESCT 559 >sp|P65477|MURE_MYCTU Tax_Id=1773 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium tuberculosis] Length = 535 Score = 694 bits (1791), Expect = 0.0 Identities = 368/511 (72%), Positives = 391/511 (76%), Gaps = 4/511 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct: 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct: 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 141 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+RL E TIGIR+ GAD+PS LTTPEAP Sbjct: 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct: 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP SALR + VVCI ITVSA +PAHWRATDVAP AGGQ Sbjct: 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct: 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct: 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct: 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct: 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 >sp|P65478|MURE_MYCBO Tax_Id=1765 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium bovis] Length = 535 Score = 694 bits (1791), Expect = 0.0 Identities = 368/511 (72%), Positives = 391/511 (76%), Gaps = 4/511 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct: 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct: 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 141 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+RL E TIGIR+ GAD+PS LTTPEAP Sbjct: 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct: 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP SALR + VVCI ITVSA +PAHWRATDVAP AGGQ Sbjct: 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct: 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct: 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct: 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct: 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 >tr|C6DPQ0|C6DPQ0_MYCTK Tax_Id=478434 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelat E ligase MurE;[Mycobacterium tuberculosis] Length = 535 Score = 694 bits (1791), Expect = 0.0 Identities = 368/511 (72%), Positives = 391/511 (76%), Gaps = 4/511 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct: 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct: 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 141 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+RL E TIGIR+ GAD+PS LTTPEAP Sbjct: 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct: 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP SALR + VVCI ITVSA +PAHWRATDVAP AGGQ Sbjct: 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct: 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct: 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct: 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct: 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 >tr|C1AQ74|C1AQ74_MYCBT Tax_Id=561275 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; EC=6.3.2.13;[Mycobacterium bovis] Length = 535 Score = 694 bits (1791), Expect = 0.0 Identities = 368/511 (72%), Positives = 391/511 (76%), Gaps = 4/511 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct: 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct: 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 141 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+RL E TIGIR+ GAD+PS LTTPEAP Sbjct: 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct: 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP SALR + VVCI ITVSA +PAHWRATDVAP AGGQ Sbjct: 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct: 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct: 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct: 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct: 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 >tr|A5U4I5|A5U4I5_MYCTA Tax_Id=419947 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate MurE;[Mycobacterium tuberculosis] Length = 535 Score = 694 bits (1791), Expect = 0.0 Identities = 368/511 (72%), Positives = 391/511 (76%), Gaps = 4/511 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct: 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct: 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 141 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+RL E TIGIR+ GAD+PS LTTPEAP Sbjct: 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct: 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP SALR + VVCI ITVSA +PAHWRATDVAP AGGQ Sbjct: 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct: 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct: 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct: 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct: 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 >tr|A1KKK1|A1KKK1_MYCBP Tax_Id=410289 (murE)SubName: Full=Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase MurE; EC=6.3.2.13;[Mycobacterium bovis] Length = 535 Score = 694 bits (1791), Expect = 0.0 Identities = 368/511 (72%), Positives = 391/511 (76%), Gaps = 4/511 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct: 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct: 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 141 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+RL E TIGIR+ GAD+PS LTTPEAP Sbjct: 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct: 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP SALR + VVCI ITVSA +PAHWRATDVAP AGGQ Sbjct: 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct: 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct: 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct: 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct: 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 >tr|A5WPD0|A5WPD0_MYCTF Tax_Id=336982 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelat E ligase murE;[Mycobacterium tuberculosis] Length = 535 Score = 694 bits (1791), Expect = 0.0 Identities = 368/511 (72%), Positives = 391/511 (76%), Gaps = 4/511 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct: 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct: 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 141 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+RL E TIGIR+ GAD+PS LTTPEAP Sbjct: 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct: 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP SALR + VVCI ITVSA +PAHWRATDVAP AGGQ Sbjct: 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct: 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct: 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct: 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct: 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 >tr|A2VJQ4|A2VJQ4_MYCTU Tax_Id=348776 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelat E ligase murE;[Mycobacterium tuberculosis C] Length = 521 Score = 694 bits (1791), Expect = 0.0 Identities = 368/511 (72%), Positives = 391/511 (76%), Gaps = 4/511 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct: 12 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 71 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct: 72 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 127 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+RL E TIGIR+ GAD+PS LTTPEAP Sbjct: 128 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 187 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct: 188 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 247 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP SALR + VVCI ITVSA +PAHWRATDVAP AGGQ Sbjct: 248 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 307 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct: 308 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 367 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct: 368 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 427 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct: 428 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 487 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct: 488 GKGHETGQRGGGRVRPFDDRVELAAALEALE 518 >sp|A0QF47|MURE_MYCA1 Tax_Id=243243 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium avium] Length = 520 Score = 679 bits (1751), Expect = 0.0 Identities = 357/511 (69%), Positives = 389/511 (76%), Gaps = 5/511 (0%) Query: 4 VESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAAL 63 V + LRPSA PGV L LA QVGAV+A GP R AAVPD +TG+TLRAQ V PGDLFAAL Sbjct: 4 VPTGLRPSAVPGVRLPALADQVGAVMA-GPDRRAAVPDVTVTGVTLRAQDVLPGDLFAAL 62 Query: 64 AGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAAL 123 G+ THGARHAA+AIERGAVAVLTD AGV ++ T P L+HP PR VLGE AA Sbjct: 63 PGATTHGARHAAEAIERGAVAVLTDAAGVAQLTG----GRTTPTLLHPRPRSVLGELAAA 118 Query: 124 VYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTP 183 VY HPS+RL E T+GIRIDGADIPS LTTP Sbjct: 119 VYAHPSERLTVIGITGTSGKTTTTYLVESGLRAAGRTAGLIGTVGIRIDGADIPSALTTP 178 Query: 184 EAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMAD 243 EAPALQA+LAAM E+ VDTVVMEVSSHAL LGRVDG RFAVGGFTNLSRDHLDFHPTMAD Sbjct: 179 EAPALQALLAAMAEQRVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMAD 238 Query: 244 YFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVG 303 YFEAKALLFDP S LR H VVCI +TVSA GQPAHWRA +VAP+G Sbjct: 239 YFEAKALLFDPNSPLRAHRAVVCIDDEAGREMAARAGDAVTVSAEGQPAHWRAVEVAPLG 298 Query: 304 AGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGR 363 GGQ+FT +DPAGV HR I LPGHYNVANCL+ALA+LDAVGVSPEQAAPGL +TRVPGR Sbjct: 299 TGGQQFTVIDPAGVQHRAGIRLPGHYNVANCLVALALLDAVGVSPEQAAPGLLQTRVPGR 358 Query: 364 LEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAA 423 +E++D GQDFLALVDYAHKPGALR VLS+L+ P RRLAVVFGAGG+RDPGKR PMG AA Sbjct: 359 MEEIDAGQDFLALVDYAHKPGALRAVLSSLKRPDRRLAVVFGAGGERDPGKRAPMGATAA 418 Query: 424 ELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDV 483 ELADLVVVTDDNPRGEDP AIRR I+AGA ESG AA+V+EI DR AI +AV WA GDV Sbjct: 419 ELADLVVVTDDNPRGEDPAAIRREILAGATESGCAAEVIEIGDRRAAIRHAVAWAGPGDV 478 Query: 484 VLIAGKGHETGQRGGAEVRPFDDRVELARAL 514 VL+AGKGHETGQR G RPFDDRVELA AL Sbjct: 479 VLVAGKGHETGQRTGEHTRPFDDRVELAEAL 509 >sp|Q73YQ3|MURE_MYCPA Tax_Id=1770 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium paratuberculosis] Length = 520 Score = 676 bits (1745), Expect = 0.0 Identities = 356/511 (69%), Positives = 388/511 (75%), Gaps = 5/511 (0%) Query: 4 VESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAAL 63 V + LRPSA PGV L LA QVGAV+A GP R AAVPD +TG+TLRAQ V PGDLFAAL Sbjct: 4 VPTGLRPSAVPGVRLPALADQVGAVMA-GPDRRAAVPDVTVTGVTLRAQDVLPGDLFAAL 62 Query: 64 AGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAAL 123 G+ THGARHAA+AIERGAVAVLTD AGV ++ T P L+HP PR VLG+ AA Sbjct: 63 PGATTHGARHAAEAIERGAVAVLTDAAGVAQLTG----GRTTPTLLHPRPRSVLGQLAAA 118 Query: 124 VYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTP 183 VY HPS+RL E T+GIRIDGADIPS LTTP Sbjct: 119 VYAHPSERLTVIGITGTSGKTTTTYLVESGLRAAGRTAGLIGTVGIRIDGADIPSALTTP 178 Query: 184 EAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMAD 243 EAPALQA+LAAM E+ VDTVVMEVSSHAL LGRVDG RFAVGGFTNLSRDHLDFHPTMAD Sbjct: 179 EAPALQALLAAMAEQRVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMAD 238 Query: 244 YFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVG 303 YFEAKALLFDP S LR H VVCI +TVSA GQPAHWRA +VAP+G Sbjct: 239 YFEAKALLFDPNSPLRAHRAVVCIDDEAGREMAARAGDAVTVSAEGQPAHWRAVEVAPLG 298 Query: 304 AGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGR 363 GGQ+FT +DPAGV HR I LPGHYNVANCL+ALA+LDAVGVSPEQAAPGL +TRVPGR Sbjct: 299 TGGQQFTVIDPAGVQHRAGIRLPGHYNVANCLVALALLDAVGVSPEQAAPGLLQTRVPGR 358 Query: 364 LEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAA 423 +E++D GQDFLALVDYAHKPGALR VLS+L+ P RRLAVVFGAGG+RDPGKR PMG AA Sbjct: 359 MEEIDAGQDFLALVDYAHKPGALRAVLSSLKRPDRRLAVVFGAGGERDPGKRAPMGATAA 418 Query: 424 ELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDV 483 ELADLVVVTDDNPRGEDP AIRR I+AG ESG AA+VVEI DR AI +AV WA GDV Sbjct: 419 ELADLVVVTDDNPRGEDPAAIRREILAGVTESGCAAEVVEIGDRRAAIRHAVAWAGPGDV 478 Query: 484 VLIAGKGHETGQRGGAEVRPFDDRVELARAL 514 VL+AGKGHETGQR G RPFDDRVELA AL Sbjct: 479 VLVAGKGHETGQRTGEHTRPFDDRVELAEAL 509 >sp|O69557|MURE_MYCLE Tax_Id=1769 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Mycobacterium leprae] Length = 530 Score = 652 bits (1682), Expect = 0.0 Identities = 345/512 (67%), Positives = 382/512 (74%), Gaps = 3/512 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRPSA GV L EL QVGAVLADGP +AA VPD +TG+TLRAQ V GDLFAALAG++ Sbjct: 11 LRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGAS 70 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGAR+A A+ERGAVAVLTD AGV ++A +VP+L+HP PR VLG AA YGH Sbjct: 71 THGARYAGVALERGAVAVLTDVAGVAELTAQA---SSVPILIHPEPRSVLGGLAAAAYGH 127 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+R+ E TIGIRIDGADIPS LTTPEAPA Sbjct: 128 PSNRMTVVGITGTSGKTTTTYMVEAGLRAGGRVVGLVGTIGIRIDGADIPSFLTTPEAPA 187 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+G +FAV GFTNLSRDHLDFHP M +YFEA Sbjct: 188 LQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEA 247 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA+LFDP S LR +VVVCI ITVSA GQPA WRATD+ G G Q Sbjct: 248 KAVLFDPHSLLRARTVVVCIDDDAGRATAARAGDAITVSALGQPASWRATDIRSPGVGAQ 307 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 EFTA+DPAGV HRV I LPG YNVANCL+ALAILD VGVSPEQA+ G R+ R+PGRLE++ Sbjct: 308 EFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERI 367 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 D GQDFLALVDYAHKPGAL VL+ L P RLAVVFGAGG+RDPGKR PMG IAAELAD Sbjct: 368 DCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAELAD 427 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPRGEDP AIRR I+ G +GGAAQVVEI DR AI YAV WA DVVL+A Sbjct: 428 LVVVTDDNPRGEDPAAIRRDILTGTVAAGGAAQVVEIGDRRAAIQYAVAWAGPDDVVLVA 487 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALES 519 GKGHETGQRG AE PFDDRVELARAL+ ++ Sbjct: 488 GKGHETGQRGAAETCPFDDRVELARALQVRDA 519 >tr|B8ZQP5|B8ZQP5_MYCLB Tax_Id=561304 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diami nopime ligase (Meso-diaminopimelate-adding enzyme);[Mycobacterium leprae] Length = 530 Score = 652 bits (1682), Expect = 0.0 Identities = 345/512 (67%), Positives = 382/512 (74%), Gaps = 3/512 (0%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRPSA GV L EL QVGAVLADGP +AA VPD +TG+TLRAQ V GDLFAALAG++ Sbjct: 11 LRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGAS 70 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGAR+A A+ERGAVAVLTD AGV ++A +VP+L+HP PR VLG AA YGH Sbjct: 71 THGARYAGVALERGAVAVLTDVAGVAELTAQA---SSVPILIHPEPRSVLGGLAAAAYGH 127 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+R+ E TIGIRIDGADIPS LTTPEAPA Sbjct: 128 PSNRMTVVGITGTSGKTTTTYMVEAGLRAGGRVVGLVGTIGIRIDGADIPSFLTTPEAPA 187 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+G +FAV GFTNLSRDHLDFHP M +YFEA Sbjct: 188 LQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEA 247 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA+LFDP S LR +VVVCI ITVSA GQPA WRATD+ G G Q Sbjct: 248 KAVLFDPHSLLRARTVVVCIDDDAGRATAARAGDAITVSALGQPASWRATDIRSPGVGAQ 307 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 EFTA+DPAGV HRV I LPG YNVANCL+ALAILD VGVSPEQA+ G R+ R+PGRLE++ Sbjct: 308 EFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERI 367 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 D GQDFLALVDYAHKPGAL VL+ L P RLAVVFGAGG+RDPGKR PMG IAAELAD Sbjct: 368 DCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAELAD 427 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 LVVVTDDNPRGEDP AIRR I+ G +GGAAQVVEI DR AI YAV WA DVVL+A Sbjct: 428 LVVVTDDNPRGEDPAAIRRDILTGTVAAGGAAQVVEIGDRRAAIQYAVAWAGPDDVVLVA 487 Query: 488 GKGHETGQRGGAEVRPFDDRVELARALEALES 519 GKGHETGQRG AE PFDDRVELARAL+ ++ Sbjct: 488 GKGHETGQRGAAETCPFDDRVELARALQVRDA 519 >tr|A3Q1M3|A3Q1M3_MYCSJ Tax_Id=164757 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetases;[Mycobacterium sp.] Length = 508 Score = 595 bits (1535), Expect = e-168 Identities = 324/509 (63%), Positives = 351/509 (68%), Gaps = 9/509 (1%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRPS G L LA QV AV A G VPD +TG+TLR Q PGDLFAAL GS+ Sbjct: 5 LRPSHPVGHALGALAEQVQAVPAPG----FPVPDIRVTGVTLRGQDALPGDLFAALPGSS 60 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 HGAR ADA+ GAVAVLTD AG + A VPVLVHP PR VLG A+ VYGH Sbjct: 61 AHGARFVADAVAAGAVAVLTDAAGAVMLGA----DPVVPVLVHPDPRAVLGAVASTVYGH 116 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS L E T+GIRIDG D PS LTTPEAP Sbjct: 117 PSQHLRVVGVTGTSGKTTTTYLVEAGLRAAGRVAGLIGTVGIRIDGRDQPSALTTPEAPD 176 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQA+LA MVE+GVDTVVMEVSSHALTLGRVDG+ FA GGFTNLSRDHLDFHPTM DYF+A Sbjct: 177 LQALLAVMVEQGVDTVVMEVSSHALTLGRVDGVHFAAGGFTNLSRDHLDFHPTMEDYFDA 236 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP S R VVC+ +TVSA+G+PA WRA DV V AG Q Sbjct: 237 KAGLFDPQSRTRAELAVVCVDDDAGRAMAIRAGRAVTVSASGRPADWRAEDVRAVEAGAQ 296 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 EF A+DPAGV H +RI LPGHYNVANCLLA A+LDAV VSPEQAAPGLR VPGRLE V Sbjct: 297 EFVAVDPAGVHHGLRIALPGHYNVANCLLAAALLDAVDVSPEQAAPGLRTATVPGRLEAV 356 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELA 426 DRGQDFLALVDYAHKPGALR VL TLR R+AVVFGAGG+RD GKR PMGR+AAELA Sbjct: 357 DRGQDFLALVDYAHKPGALRAVLETLRGQGTGRIAVVFGAGGNRDAGKREPMGRVAAELA 416 Query: 427 DLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLI 486 DLVVVTDDNPR EDP IR I+AGA +GG A VVE+ DR EAI +AV WAR+GDVVL+ Sbjct: 417 DLVVVTDDNPRDEDPATIRAAIMAGARAAGGGADVVEVGDRREAIAHAVRWARSGDVVLV 476 Query: 487 AGKGHETGQRGGAEVRPFDDRVELARALE 515 AGKGHETGQ PFDDRVELA LE Sbjct: 477 AGKGHETGQTAAGRTHPFDDRVELAELLE 505 >tr|Q1B6W6|Q1B6W6_MYCSS Tax_Id=164756 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Mycobacterium sp.] Length = 508 Score = 595 bits (1534), Expect = e-168 Identities = 324/509 (63%), Positives = 351/509 (68%), Gaps = 9/509 (1%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRPS G L LA QV AV A G VPD +TG+TLR Q PGDLFAAL GS+ Sbjct: 5 LRPSHPVGHALGALAEQVQAVPAPG----FPVPDIRVTGVTLRGQDALPGDLFAALPGSS 60 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 HGAR ADA+ GAVAVLTD AG + A VPVLVHP PR VLG A+ VYGH Sbjct: 61 AHGARFVADAVAAGAVAVLTDAAGAVMLGA----DPVVPVLVHPDPRAVLGAVASTVYGH 116 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS L E T+GIRIDG D PS LTTPEAP Sbjct: 117 PSQHLRVVGVTGTSGKTTTTYLVEAGLRAAGRVAGLIGTVGIRIDGRDQPSALTTPEAPD 176 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQA+LA MVE+GVDTVVMEVSSHALTLGRVDG+ FA GGFTNLSRDHLDFHPTM DYF+A Sbjct: 177 LQALLAVMVEQGVDTVVMEVSSHALTLGRVDGVHFAAGGFTNLSRDHLDFHPTMEDYFDA 236 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP S R VVC+ +TVSA+G+PA WRA DV V AG Q Sbjct: 237 KAGLFDPQSRTRAELAVVCVDDDAGRAMAIRAGRAVTVSASGRPADWRAEDVRAVEAGAQ 296 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 EF A+DPAGV H +RI LPGHYNVANC+LA A+LDAV VSPEQAAPGLR VPGRLE V Sbjct: 297 EFVAVDPAGVHHGLRIALPGHYNVANCVLAAALLDAVDVSPEQAAPGLRTATVPGRLEAV 356 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQR-RLAVVFGAGGDRDPGKRGPMGRIAAELA 426 DRGQDFLALVDYAHKPGALR VL TLR + R+AVVFGAGG+RD GKR PMGR+AAELA Sbjct: 357 DRGQDFLALVDYAHKPGALRAVLETLRGQGKGRIAVVFGAGGNRDAGKREPMGRVAAELA 416 Query: 427 DLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLI 486 DLVVVTDDNPR EDP IR I+AGA +GG A VVEI DR EAI +AV WAR GDVVL+ Sbjct: 417 DLVVVTDDNPRDEDPATIRAAIMAGARAAGGGADVVEIGDRREAIAHAVRWARPGDVVLV 476 Query: 487 AGKGHETGQRGGAEVRPFDDRVELARALE 515 AGKGHETGQ PFDDRVELA LE Sbjct: 477 AGKGHETGQTAAGRTHPFDDRVELAELLE 505 >tr|A1UI59|A1UI59_MYCSK Tax_Id=189918 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Mycobacterium sp.] Length = 508 Score = 595 bits (1534), Expect = e-168 Identities = 324/509 (63%), Positives = 351/509 (68%), Gaps = 9/509 (1%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRPS G L LA QV AV A G VPD +TG+TLR Q PGDLFAAL GS+ Sbjct: 5 LRPSHPVGHALGALAEQVQAVPAPG----FPVPDIRVTGVTLRGQDALPGDLFAALPGSS 60 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 HGAR ADA+ GAVAVLTD AG + A VPVLVHP PR VLG A+ VYGH Sbjct: 61 AHGARFVADAVAAGAVAVLTDAAGAVMLGA----DPVVPVLVHPDPRAVLGAVASTVYGH 116 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS L E T+GIRIDG D PS LTTPEAP Sbjct: 117 PSQHLRVVGVTGTSGKTTTTYLVEAGLRAAGRVAGLIGTVGIRIDGRDQPSALTTPEAPD 176 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQA+LA MVE+GVDTVVMEVSSHALTLGRVDG+ FA GGFTNLSRDHLDFHPTM DYF+A Sbjct: 177 LQALLAVMVEQGVDTVVMEVSSHALTLGRVDGVHFAAGGFTNLSRDHLDFHPTMEDYFDA 236 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA LFDP S R VVC+ +TVSA+G+PA WRA DV V AG Q Sbjct: 237 KAGLFDPQSRTRAELAVVCVDDDAGRAMAIRAGRAVTVSASGRPADWRAEDVRAVEAGAQ 296 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 EF A+DPAGV H +RI LPGHYNVANC+LA A+LDAV VSPEQAAPGLR VPGRLE V Sbjct: 297 EFVAVDPAGVHHGLRIALPGHYNVANCVLAAALLDAVDVSPEQAAPGLRTATVPGRLEAV 356 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQR-RLAVVFGAGGDRDPGKRGPMGRIAAELA 426 DRGQDFLALVDYAHKPGALR VL TLR + R+AVVFGAGG+RD GKR PMGR+AAELA Sbjct: 357 DRGQDFLALVDYAHKPGALRAVLETLRGQGKGRIAVVFGAGGNRDAGKREPMGRVAAELA 416 Query: 427 DLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLI 486 DLVVVTDDNPR EDP IR I+AGA +GG A VVEI DR EAI +AV WAR GDVVL+ Sbjct: 417 DLVVVTDDNPRDEDPATIRAAIMAGARAAGGGADVVEIGDRREAIAHAVRWARPGDVVLV 476 Query: 487 AGKGHETGQRGGAEVRPFDDRVELARALE 515 AGKGHETGQ PFDDRVELA LE Sbjct: 477 AGKGHETGQTAAGRTHPFDDRVELAELLE 505 >tr|A0R021|A0R021_MYCS2 Tax_Id=246196 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase;[Mycobacterium smegmatis] Length = 520 Score = 581 bits (1498), Expect = e-164 Identities = 312/513 (60%), Positives = 358/513 (69%), Gaps = 10/513 (1%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAA-VPDTLITGMTLRAQAVQPGDLFAALAGS 66 LRPS G LA LA VGAV ++ P +++ + +TG+TLR Q QPGDLFAAL G+ Sbjct: 5 LRPSRPVGHHLAPLAAAVGAVASENPAGSSSDLAAVHVTGVTLRGQDAQPGDLFAALPGA 64 Query: 67 ATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGT--VPVLVHPAPRGVLGEAAALV 124 + HGAR AADA+ GAVAVLTDP+G ++ GT VPVLVHPAPR VLGEAAA+V Sbjct: 65 SAHGARFAADAVAAGAVAVLTDPSGADLLA------GTLDVPVLVHPAPRSVLGEAAAIV 118 Query: 125 YGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPE 184 YG P++RL E T+G+RIDG D+PS LTTPE Sbjct: 119 YGRPAERLRVVGVTGTSGKTTTTYLAEAGLRAAGRVAGLIGTVGVRIDGTDLPSALTTPE 178 Query: 185 APALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADY 244 APALQA+LA MVERGVDTVVMEVSSHAL GRVDGI FAVGGFTNLSRDHLDFHPTMADY Sbjct: 179 APALQALLALMVERGVDTVVMEVSSHALAQGRVDGIGFAVGGFTNLSRDHLDFHPTMADY 238 Query: 245 FEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGA 304 FEAKA LFDP S + V+C+ +TVS +G A WR + G Sbjct: 239 FEAKARLFDPQSPNHAAAAVICVDDQYGVQMAARAETPLTVSTSGAAADWRVEKITTAGP 298 Query: 305 GGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRL 364 G QEF +DP G+ H++ +GLPG YNVAN LA+A+LDAVGVSPEQAAPGLR VPGRL Sbjct: 299 GAQEFVLVDPGGMHHQLGVGLPGRYNVANAALAVALLDAVGVSPEQAAPGLRTATVPGRL 358 Query: 365 EQVDRGQDFLALVDYAHKPGALREVLSTLRNPQ-RRLAVVFGAGGDRDPGKRGPMGRIAA 423 E +D GQDFLALVDYAHKPGAL+ VL TLR + RR+AVVFGAGGDRDPGKR PMGR+ A Sbjct: 359 ESIDLGQDFLALVDYAHKPGALQAVLETLRAAEPRRIAVVFGAGGDRDPGKREPMGRVTA 418 Query: 424 ELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDV 483 ELADLVVVTDDNPR EDP IR I+AGA A++VEI DR AI +AV WA+ GD+ Sbjct: 419 ELADLVVVTDDNPRSEDPATIRSAILAGARAVASDAEIVEIGDRRAAIDHAVAWAQPGDI 478 Query: 484 VLIAGKGHETGQRGGAEVRPFDDRVELARALEA 516 VLIAGKGHE+GQ G RPFDDR ELA ALEA Sbjct: 479 VLIAGKGHESGQTVGDHTRPFDDRDELAAALEA 511 >tr|A1TAX3|A1TAX3_MYCVP Tax_Id=350058 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Mycobacterium vanbaalenii] Length = 497 Score = 573 bits (1476), Expect = e-161 Identities = 312/497 (62%), Positives = 344/497 (69%), Gaps = 10/497 (2%) Query: 21 LAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAADAIER 80 LA V AV A G PD +TG+TLR Q QPGDLFAAL GS HG R+AA+A+ R Sbjct: 2 LADLVAAVAAGG----GGAPDVQVTGVTLRGQDAQPGDLFAALPGSRAHGGRYAAEAVGR 57 Query: 81 GAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXX 140 GAVAVLTD AG I++ G VPVLVHP PR VLGE A+ VYG PS L Sbjct: 58 GAVAVLTDAAGEAEIASRGAPD--VPVLVHPDPRAVLGELASAVYGRPSQHLRVIGVTGT 115 Query: 141 XXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGV 200 E T+G+RIDG P LTTPEAP LQA+LA M+E+GV Sbjct: 116 SGKTTTTYLVEAGLRAAGRVAGLIGTVGVRIDGRQQPGGLTTPEAPELQALLATMLEQGV 175 Query: 201 DTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRG 260 DTVVMEVSSHALTLGRVDG+ FAVGGFTNLSRDHLDFHPTM DYF+AKA LFDPA A Sbjct: 176 DTVVMEVSSHALTLGRVDGVSFAVGGFTNLSRDHLDFHPTMEDYFDAKARLFDPACATHA 235 Query: 261 HSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPAGVGHR 320 V+C+ +TVS TG PA WRA V G G Q+F A+DPAGV H Sbjct: 236 ARSVICVDDEWGRAMAARARRPVTVSTTG-PADWRAEQVRSAGGGAQDFVAVDPAGVHHG 294 Query: 321 VRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYA 380 + IGLPG YNVANCLLA+A+LDAVGVSPEQAAPG+R+ VPGRLE VDRGQ FLALVDYA Sbjct: 295 LEIGLPGGYNVANCLLAIALLDAVGVSPEQAAPGVRDATVPGRLESVDRGQPFLALVDYA 354 Query: 381 HKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGE 439 HKPGALR VL TLR RLAVVFGAGG+RD GKR PMGR+AAELADLVVVTDDNPR E Sbjct: 355 HKPGALRAVLQTLREQCTGRLAVVFGAGGNRDQGKREPMGRVAAELADLVVVTDDNPRDE 414 Query: 440 DPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGA 499 DP IR I+AGAA G A+VVEI DR AIG+A WAR GD+VLIAGKGHE GQ G Sbjct: 415 DPAVIRAAILAGAA--GARAEVVEIGDRRAAIGHAAGWARAGDIVLIAGKGHEAGQTSGG 472 Query: 500 EVRPFDDRVELARALEA 516 + RPFDDR ELA ALEA Sbjct: 473 QTRPFDDRDELAAALEA 489 >tr|A4TBF0|A4TBF0_MYCGI Tax_Id=350054 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; Flags: Precursor;[Mycobacterium gilvum] Length = 512 Score = 566 bits (1458), Expect = e-159 Identities = 316/513 (61%), Positives = 350/513 (68%), Gaps = 12/513 (2%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRPS G+PL LA V A AD A VPD +TG+TLR Q Q GDLFAAL GS Sbjct: 3 LRPSHPVGMPLGALADLVCAEPAD----AGPVPDLQVTGVTLRGQHAQAGDLFAALPGSK 58 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 HGAR+AADA+ERGAVAVLTD GV+ I+A G VP+LVHPAPR VLGE AA V+G Sbjct: 59 AHGARYAADAVERGAVAVLTDADGVSEIAAHG--GPAVPILVHPAPRSVLGEVAAAVFGR 116 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+ L E T+G+RIDG P LTTPEAP Sbjct: 117 PSEHLRVIGVTGTSGKTTTTYLVEAGLRSAGRVAGLIGTVGVRIDGRAQPGGLTTPEAPD 176 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 LQA+LAAM+E+GVDTVVMEVSSHALTLGRVDG+ FAVGGFTNLSRDHLDFHPTM DYFEA Sbjct: 177 LQALLAAMLEQGVDTVVMEVSSHALTLGRVDGVSFAVGGFTNLSRDHLDFHPTMQDYFEA 236 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQ 307 KA L DP S V+C+ +TVS TG A W +V + G Q Sbjct: 237 KARLVDPTSPTHAARSVICVDDEWGRAMAARADAPVTVSVTGD-ADWWVQEVRALDGGVQ 295 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 +F A+DPAGV H + IGLPG YNVANCLLA+A+LDAV VSPEQAAPGLR+ VPGRLE V Sbjct: 296 DFLAVDPAGVHHALEIGLPGGYNVANCLLAVALLDAVDVSPEQAAPGLRDATVPGRLEAV 355 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELA 426 DRGQ FLALVDYAHKPGAL VL TLR RLAVVFGAGGDRD GKR PMGR+AAELA Sbjct: 356 DRGQPFLALVDYAHKPGALAAVLQTLREQCAGRLAVVFGAGGDRDQGKREPMGRVAAELA 415 Query: 427 DLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLI 486 DLVVVTDDNPRGEDP IR I+ GA+ AQ VEI DR AI +AV WAR GD+VLI Sbjct: 416 DLVVVTDDNPRGEDPAVIRAAILRGAS----GAQTVEIGDRRAAIVHAVQWAREGDIVLI 471 Query: 487 AGKGHETGQRGGAEVRPFDDRVELARALEALES 519 AGKGHE GQ RPFDDR ELA ALE L++ Sbjct: 472 AGKGHEAGQTSQGRTRPFDDRDELAAALETLQT 504 >tr|B1MP32|B1MP32_MYCA9 Tax_Id=561007 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase MurE;[Mycobacterium abscessus] Length = 515 Score = 480 bits (1235), Expect = e-133 Identities = 272/484 (56%), Positives = 315/484 (65%), Gaps = 12/484 (2%) Query: 42 TLITGMTLRAQAVQPGDLFAALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCV 101 T + G+TLRAQ + GDLFAAL G++THGA+ A++A+ GA AVLTD AG ++ G Sbjct: 35 TTVGGVTLRAQDARTGDLFAALPGTSTHGAQFASEAVSAGAAAVLTDAAGAELVAGQGL- 93 Query: 102 PGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXX 161 + VLVHP PR VLGE AA VYG PS L E Sbjct: 94 --DIAVLVHPVPRSVLGELAATVYGEPSRHLQVVGVTGTSGKTTTTYLVEAGLRAAGKRV 151 Query: 162 XXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIR 221 T+G+RIDG D+PS LTTPEAPALQ +LA MV+RGVDTVVMEVSSHAL L RVDG R Sbjct: 152 GLIGTVGVRIDGEDVPSALTTPEAPALQELLAEMVQRGVDTVVMEVSSHALALNRVDGTR 211 Query: 222 FAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRGHSVVVCI----XXXXXXXXXX 277 FAVG FTNLSRDHLDFHP M DYF KA LF S R H VVCI Sbjct: 212 FAVGAFTNLSRDHLDFHPDMQDYFATKARLFRRDSPQRAHRSVVCIDDDAGRAMAELARE 271 Query: 278 XXXXXITVSA-TGQPAHWRATDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLL 336 TVS+ G A WR ++VA GGQ F A P + I LPGHYNVANCL+ Sbjct: 272 AGPDVTTVSSLDGGVADWRCSNVAVGHDGGQRFVANGP-DRDTELTIALPGHYNVANCLV 330 Query: 337 ALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNP 396 A+AILD +GVS AAPG+ VPGR+E V GQ FLA+VDYAHKPGALR VL +LR+ Sbjct: 331 AIAILDVLGVSAATAAPGIATAGVPGRMEAVAAGQPFLAVVDYAHKPGALRAVLESLRSH 390 Query: 397 Q-RRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAES 455 + RLAVVFGAGG+RD GKR MG++AAELADLVVVTDDNPR E+P AIR I++G + Sbjct: 391 RDGRLAVVFGAGGNRDRGKRADMGKVAAELADLVVVTDDNPRNEEPAAIRTEIISGT--T 448 Query: 456 GGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALE 515 G AQ++EI DR AI +A WAR GD VL+AGKGHE+GQ+ G PFDDRVEL ALE Sbjct: 449 GSEAQIIEIGDRRAAIDFATLWARPGDTVLVAGKGHESGQKTGDVTVPFDDRVELRAALE 508 Query: 516 ALES 519 AL S Sbjct: 509 ALGS 512 >tr|Q5YYY4|Q5YYY4_NOCFA Tax_Id=37329 (murE)SubName: Full=Putative UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase;[Nocardia farcinica] Length = 536 Score = 448 bits (1152), Expect = e-124 Identities = 275/523 (52%), Positives = 313/523 (59%), Gaps = 28/523 (5%) Query: 5 ESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVP-DTLITGMTLRAQAVQPGDLFAAL 63 + VLRP P PL + GA H AA VP D ++TG+ R+ AVQPGDLFAAL Sbjct: 19 QPVLRPVDPPSTPLTTVLELTGA------HAAAPVPADVVVTGIEQRSGAVQPGDLFAAL 72 Query: 64 AGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAAL 123 G+ HGAR A DA+ RGAVAV TD G + L TVPVLV PR VLGE +A Sbjct: 73 PGAHAHGARFAHDAVARGAVAVFTDAEGARVLDGL-----TVPVLVRERPREVLGELSAA 127 Query: 124 VYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTP 183 VYG PS RL E TI RI G +PS LTTP Sbjct: 128 VYGQPSQRLRLIGITGTSGKTTTSYLVEAGLAAAGLSTALIGTIETRIGGRRVPSALTTP 187 Query: 184 EAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMAD 243 EAP L AM A MVE+GV VVMEVSSHAL LGRVDG+RF VG FTNLS+DHLDFH D Sbjct: 188 EAPQLHAMFALMVEQGVQAVVMEVSSHALALGRVDGVRFDVGAFTNLSQDHLDFHADFED 247 Query: 244 YFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWR-ATDVAPV 302 YF AK LF+P S + + VVC+ ITVS TG+ A WR A VA V Sbjct: 248 YFAAKRRLFEPQSPVAARTAVVCVDDAWGRRLAEGLAAPITVSTTGE-ADWRVAGGVATV 306 Query: 303 GAGGQEFTALDPAG-VGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVP 361 GA QEFTA PAG +G VR+ LPG YNVAN LLA+A+ A P AAP L VP Sbjct: 307 GA-EQEFTAAGPAGELG--VRLRLPGRYNVANALLAVAVCAAARADPAVAAPALATVDVP 363 Query: 362 GRLEQVDRGQDFLALVDYAHKPGALREVLSTLR------NPQR--RLAVVFGAGGDRDPG 413 GR+++V+RGQDFLA+VDYAHKP AL V++TLR +P+ RLAVV GAGGDRD G Sbjct: 364 GRMQRVERGQDFLAVVDYAHKPAALESVIATLREHLAAADPEHPGRLAVVVGAGGDRDAG 423 Query: 414 KRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAE--SGGAAQVVEIADRGEAI 471 KR MG A ADL+V+TDDNPR EDP IR + AGA E + +V EI DR AI Sbjct: 424 KRALMGAAGARGADLLVITDDNPRTEDPATIRAALRAGALEVPAEVRGEVREIGDRAAAI 483 Query: 472 GYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARAL 514 AV WAR GD VL+AGKGHETGQ PFDDR LA AL Sbjct: 484 EAAVAWARRGDAVLVAGKGHETGQEIAGVKHPFDDREVLAAAL 526 >tr|C2ATS6|C2ATS6_TSUPA Tax_Id=521096 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Tsukamurella paurometabola DSM 20162] Length = 522 Score = 440 bits (1132), Expect = e-121 Identities = 253/518 (48%), Positives = 309/518 (59%), Gaps = 14/518 (2%) Query: 6 SVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAG 65 ++ RP+ G L E+A QV V++ + + +G T+RAQ +PGDLF + G Sbjct: 5 TLTRPAHPRGATLTEIAAQVPGVISVPASSDSG--EVRCSGATIRAQDARPGDLFCGVPG 62 Query: 66 SATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVY 125 ++THGAR AA+A+ GAVAVLTD AG ++ G VPVL+H PR VLG AAA++Y Sbjct: 63 TSTHGARFAAEAVAAGAVAVLTDSAGAAVLAEAGV---DVPVLLHDDPRSVLGPAAAVIY 119 Query: 126 GHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEA 185 G PS ++ E T+G RI G D+P++LTTPE Sbjct: 120 GAPSTKMTLVGITGTSGKTTTSFLVEAALGATQATTGLIGTVGTRIAGVDVPTSLTTPEG 179 Query: 186 PALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYF 245 ALQ + A+MVE+GV + VMEVSSHAL RV G RFAVG FTNLS+DHLD+HPTM DYF Sbjct: 180 TALQGLFASMVEQGVTSAVMEVSSHALAQNRVGGTRFAVGAFTNLSQDHLDYHPTMEDYF 239 Query: 246 EAKALLFDPASALRG---HSVVVCIXXXXXXXXXXXXXXX----ITVSATGQPAHWRATD 298 AKALLF P + G V+C+ +TV+ TG PA W A Sbjct: 240 AAKALLFVPDESGDGPVCEQAVICVDDEWGNRMADLRRDAGLPLVTVATTG-PADWTAGA 298 Query: 299 VAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRET 358 V+ G Q FT P G +GLPG YNVAN LAL + GV A G+ Sbjct: 299 VSAHADGTQRFTLTGPGGQSFSATVGLPGAYNVANAALALVVAHEAGVPLADAVRGIGAV 358 Query: 359 RVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQR-RLAVVFGAGGDRDPGKRGP 417 VPGR++++DRGQDFLA+VDYAHKP AL V++TLR R+AVV GAGGDRD GKR Sbjct: 359 AVPGRVQRIDRGQDFLAVVDYAHKPAALDAVIATLRGQTAGRIAVVVGAGGDRDRGKRPL 418 Query: 418 MGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDW 477 MG +AA A+LV+VTDDNPR EDP AIR + AGA G +V EI DR AI AVDW Sbjct: 419 MGEVAARAAELVIVTDDNPRTEDPAAIRAAVRAGAEAVPGGGEVREIGDRRAAITEAVDW 478 Query: 478 ARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALE 515 ARTGDVVLIAGKGHE GQ PFDDR ELA AL+ Sbjct: 479 ARTGDVVLIAGKGHEAGQEINGVKHPFDDRDELAAALD 516 >tr|D0LAT6|D0LAT6_GORB4 Tax_Id=526226 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Gordonia bronchialis] Length = 556 Score = 440 bits (1131), Expect = e-121 Identities = 261/535 (48%), Positives = 314/535 (58%), Gaps = 24/535 (4%) Query: 3 EVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAA 62 +V + LRP++ ++ L+ GA L A T +TG+TLRAQ V+ GDLFAA Sbjct: 17 QVSAALRPTSVAPTAVSVLSTSTGARL---DLIGGAESATEVTGVTLRAQEVRSGDLFAA 73 Query: 63 LAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAA 122 L GS THGAR AADA+ GA A+LTDPAG +S + +V LVHP PR VLG +A Sbjct: 74 LPGSTTHGARFAADAVAAGATAILTDPAGRAELSRVLPPEASVVALVHPEPRTVLGGVSA 133 Query: 123 LVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTT 182 +YG+PS RL E T+ RIDG PS+LTT Sbjct: 134 RIYGNPSQRLKLIGITGTSGKTTTSYMVEAALLAAGSSVGLIGTVETRIDGVAQPSSLTT 193 Query: 183 PEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMA 242 PEAP LQA+LA M+ERGVD VVMEVSSHAL LGRVDG FA+G FTNLS+DHLDFHPTMA Sbjct: 194 PEAPTLQALLAVMLERGVDAVVMEVSSHALALGRVDGSHFALGAFTNLSQDHLDFHPTMA 253 Query: 243 DYFEAKALLFDPASALRGHSVVVCI--------XXXXXXXXXXXXXXXITVSATGQPAHW 294 YFEAKA LF P+S + V+C+ +TVS G PA W Sbjct: 254 AYFEAKAQLFVPSSPVHAVRSVICVDDEWGARMAELARPAARQSARQPVTVSTGGVPAQW 313 Query: 295 RATDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPG 354 A + + V A G T + + + LPG YNVAN LLA+A+ D GV A Sbjct: 314 HAAE-SVVDADGTSRTPITGTDGDAELVVPLPGRYNVANALLAVAVADCAGVDAATAIGA 372 Query: 355 LRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQR------RLAVVFGAGG 408 + VPGRL++VDRGQ FLALVDYAHKPGA++ VL+TLR R+A+V GAGG Sbjct: 373 IATVSVPGRLQRVDRGQPFLALVDYAHKPGAVQAVLATLRAQAAARAEAGRVAIVIGAGG 432 Query: 409 DRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESG------GAAQVV 462 DRD KR MG AA A+ VVVTDDNPR EDP AIR ++AGA G GA +V Sbjct: 433 DRDTAKRPLMGEAAARGAEFVVVTDDNPRTEDPAAIRAEVLAGARAVGRADRPAGAEEVR 492 Query: 463 EIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEAL 517 E+ R EAI A+ WAR GD VLIAGKGHETGQ PFDDR +A+ L+ L Sbjct: 493 EVGGRAEAIATALHWARPGDTVLIAGKGHETGQEINGVKHPFDDRDVVAQVLDGL 547 >tr|C1AU60|C1AU60_RHOOB Tax_Id=632772 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Rhodococcus opacus] Length = 524 Score = 421 bits (1083), Expect = e-116 Identities = 245/522 (46%), Positives = 305/522 (58%), Gaps = 15/522 (2%) Query: 3 EVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAA 62 +V LRP+ ++ LA GA + + P A ++TG+ LRAQ + GDLFAA Sbjct: 2 KVTDGLRPAQPVRTTVSALAALAGARV-EAPSGTAE--HVIVTGVDLRAQGIVEGDLFAA 58 Query: 63 LAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAA 122 L G+ HGA AADA++RGA A+LTD AG+ +SALG PVLVH PRGVLGE +A Sbjct: 59 LPGARAHGAEFAADALDRGATAILTDEAGLALVSALGT---DAPVLVHDDPRGVLGELSA 115 Query: 123 LVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTT 182 +YG PS+++ E TI R+ G +PS LTT Sbjct: 116 TIYGRPSEKMQVIGITGTSGKTTTSYLVEGALNAAGRTTGLVGTIETRMSGRRVPSALTT 175 Query: 183 PEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMA 242 PEAP L A+ A M+E+G+DTVVMEVSSHAL+LGRVDG+RF VG FTNLS+DHLDFH Sbjct: 176 PEAPQLHALFAVMLEQGIDTVVMEVSSHALSLGRVDGVRFDVGAFTNLSQDHLDFHRDFE 235 Query: 243 DYFEAKALLFDPASALRGHSVVVCI----XXXXXXXXXXXXXXXITVSATGQP--AHWRA 296 DYF AKA LF S++ V+C+ TV+ T + A W A Sbjct: 236 DYFAAKARLFAAESSVHAQHAVICVDDVWGRRMAEVARGAHSIVTTVATTPETGGAVWTA 295 Query: 297 TDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLR 356 +G Q+F G V + LPG YNVAN LA+A+ +GV P A G+ Sbjct: 296 GPATVSASGSQKFALTTAEGTTLDVELRLPGQYNVANASLAVALCAVLGVDPRDAVAGIA 355 Query: 357 ETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQR-RLAVVFGAGGDRDPGKR 415 VPGR++++DRGQDFLA+VDYAHKP A+ V++TLR R R+AVV GAGGDRD GKR Sbjct: 356 GVDVPGRVQRIDRGQDFLAVVDYAHKPAAVEAVIATLREQARGRVAVVVGAGGDRDAGKR 415 Query: 416 GPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGA--AESGGAAQVVEIADRGEAIGY 473 MG AA ADL+++TDDNPR EDP IR I GA QV E+ADR +AI Sbjct: 416 PLMGAAAARGADLLIITDDNPRTEDPATIRAAIREGALGVPESERGQVWEVADRAKAIAD 475 Query: 474 AVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALE 515 AV WA+ GDVVL+AGKGHE GQ PFDDR L A+E Sbjct: 476 AVGWAQAGDVVLVAGKGHEIGQEIHGVKYPFDDRAVLGDAIE 517 >tr|C1A0Y0|C1A0Y0_RHOE4 Tax_Id=234621 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Rhodococcus erythropolis] Length = 544 Score = 421 bits (1082), Expect = e-115 Identities = 240/515 (46%), Positives = 297/515 (57%), Gaps = 9/515 (1%) Query: 9 RPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSAT 68 RP+ + L+ GA L + + ++ G+ LRAQ + DLFAAL G+ T Sbjct: 17 RPTQPVATAITALSELSGARLEWVGQPGSQSSEVVVKGVDLRAQGIVADDLFAALPGART 76 Query: 69 HGARHAADAIERGAVAVLTDPAGVTAISALGCVPG-TVPVLVHPAPRGVLGEAAALVYGH 127 HGA+ A DA+ RGA A+LTD AG+ I A G P +VPVLVHP PR VLGE +A +YG Sbjct: 77 HGAQFAVDALGRGATAILTDEAGLELIEAAGKAPDRSVPVLVHPNPRDVLGEISAEIYGR 136 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 PS+++ E TI RIDG +PS LTTPEAP Sbjct: 137 PSEKMQVVGITGTSGKTTTSYLLEAAIAGAGRKPGLVGTIETRIDGRRVPSALTTPEAPQ 196 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 L A+ A M E+G+DTVVMEVSSHAL LGRVDGIRF +G FTNLS+DHLDFH +YF+A Sbjct: 197 LHALFAVMAEQGIDTVVMEVSSHALALGRVDGIRFDIGAFTNLSQDHLDFHRDFEEYFQA 256 Query: 248 KALLFDPASALRGHSVVVCI-----XXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPV 302 KA LFDP S +R VVC+ TVS + A W+ V Sbjct: 257 KARLFDPESTVRAEHAVVCVDDVWGRRMAELAATDESDAVTTVSTSTAEAEWKVGAVEVA 316 Query: 303 GAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPG 362 G Q F + P G V + LPG YNVAN LAL + A G+ P+ A L VPG Sbjct: 317 EDGSQTFELVGPDGQSWPVSLRLPGRYNVANAALALTVSFAAGLDPDAAVRALGTVDVPG 376 Query: 363 RLEQVDRGQDFLALVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRI 421 R++++DRGQ FLA+VDYAHKP AL V++TLRN R+AVV GAGGDRD GKR MG Sbjct: 377 RVQRIDRGQSFLAVVDYAHKPAALEAVIATLRNQVPGRVAVVVGAGGDRDAGKRTLMGEA 436 Query: 422 AAELADLVVVTDDNPRGEDPGAIRRTIVAGAAE--SGGAAQVVEIADRGEAIGYAVDWAR 479 A ADL++VTDDNPR EDP IR +++ GA + ++ E+ DR AI AV WA+ Sbjct: 437 GARGADLLIVTDDNPRTEDPAKIRASVMQGAIDVPESERGEIREVGDRALAIEQAVRWAQ 496 Query: 480 TGDVVLIAGKGHETGQRGGAEVRPFDDRVELARAL 514 GDVVL+AGKGHE GQ PFDDR L + Sbjct: 497 PGDVVLVAGKGHEVGQEIDGVKHPFDDREVLGEMI 531 >tr|Q0SHR6|Q0SHR6_RHOSR Tax_Id=101510 (murE1)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Rhodococcus sp.] Length = 537 Score = 419 bits (1076), Expect = e-115 Identities = 244/522 (46%), Positives = 302/522 (57%), Gaps = 15/522 (2%) Query: 3 EVESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAA 62 +V LRP+ ++ LA GA + A V ++TG+ LRAQ + GDLFAA Sbjct: 15 KVTDSLRPAQPVRTTVSALAALAGARVEAPTGTAEHV---IVTGVDLRAQGIVEGDLFAA 71 Query: 63 LAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAA 122 L G+ HGA AADA+ RGA A+LTD AG +SALG +PVLVH PRGVLGE +A Sbjct: 72 LPGARAHGAEFAADALARGATAILTDEAGFALVSALG---SDMPVLVHDDPRGVLGELSA 128 Query: 123 LVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTT 182 +YG PS+++ E TI R+ G +PS LTT Sbjct: 129 TIYGRPSEKMQVIGITGTSGKTTTSYLVEAALTAAGRTTGLVGTIETRMRGRRVPSALTT 188 Query: 183 PEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMA 242 PEAP L A+ A M+E+G+DTVVMEVSSHAL+LGRVDG+RF VG FTNLS+DHLDFH Sbjct: 189 PEAPQLHALFAVMLEQGIDTVVMEVSSHALSLGRVDGVRFDVGAFTNLSQDHLDFHRDFE 248 Query: 243 DYFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSAT------GQPAHWRA 296 DYF AKA LF S++ V+CI ++ T + A W A Sbjct: 249 DYFAAKARLFAADSSVHAQHAVICIDDVWGQRMADVARGAHSIVTTVATTPDSEGAVWTA 308 Query: 297 TDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLR 356 +G Q F G V + LPG YNVAN LA+A+ A+GV P A G+ Sbjct: 309 GPATVSPSGSQTFALTTAEGTTLDVELRLPGQYNVANASLAVALCAALGVDPRDAVEGIA 368 Query: 357 ETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQR-RLAVVFGAGGDRDPGKR 415 VPGR++++DRGQDFLA+VDYAHKP A+ V++TLR R R+AVV GAGGDRD GKR Sbjct: 369 GVDVPGRVQRIDRGQDFLAVVDYAHKPAAVEAVIATLREQVRGRVAVVVGAGGDRDAGKR 428 Query: 416 GPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGA--AESGGAAQVVEIADRGEAIGY 473 MG AA ADL+++TDDNPR EDP IR + GA QV E+ADR +AI Sbjct: 429 PLMGAAAARGADLLIITDDNPRSEDPAKIRAAVREGALGVPESERGQVWEVADRAKAIAD 488 Query: 474 AVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALE 515 AV WA+ GDVVL+AGKGHE GQ PFDDR L A+E Sbjct: 489 AVGWAQAGDVVLVAGKGHEIGQEIHGVKYPFDDRDVLGDAIE 530 >tr|C3JJ53|C3JJ53_RHOER Tax_Id=596309 SubName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Rhodococcus erythropolis SK121] Length = 544 Score = 418 bits (1074), Expect = e-114 Identities = 234/483 (48%), Positives = 285/483 (59%), Gaps = 9/483 (1%) Query: 41 DTLITGMTLRAQAVQPGDLFAALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGC 100 + ++ G+ LRAQ + DLFAAL G+ THGA+ A DA+ RGA A+LTD AG+ I A Sbjct: 49 EVVVKGVDLRAQGIVTDDLFAALPGARTHGAQFAVDALGRGATAILTDEAGLELIEAADK 108 Query: 101 VPG-TVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXX 159 P +VPVLVHP PR VLGE +A +YG PS+++ E Sbjct: 109 APDRSVPVLVHPNPRDVLGEISAEIYGRPSEKMQVVGITGTSGKTTTSYLLEAAIAGAGR 168 Query: 160 XXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDG 219 TI RIDG +PS LTTPEAP L A+ A M E+G+DTVVMEVSSHAL LGRVDG Sbjct: 169 KPGLVGTIETRIDGRRVPSALTTPEAPQLHALFAVMAEQGIDTVVMEVSSHALALGRVDG 228 Query: 220 IRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRGHSVVVCI-----XXXXXXX 274 IRF +G FTNLS+DHLDFH +YF+AKA LFDP S +R VVC+ Sbjct: 229 IRFDIGAFTNLSQDHLDFHRDFEEYFQAKARLFDPESTVRAEHAVVCVDDVWGRRMAELA 288 Query: 275 XXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANC 334 TVS + A W V G Q F + P G V + LPG YNVAN Sbjct: 289 ATDESDAVTTVSTSTAEAEWTVGAVEVAEDGSQTFELVGPDGQSWPVSLRLPGRYNVANA 348 Query: 335 LLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLR 394 LAL + A G+ P+ A L VPGR++++DRGQ FLA+VDYAHKP AL V++TLR Sbjct: 349 ALALTVSFAAGLDPDAAVRALGTVDVPGRVQRIDRGQSFLAVVDYAHKPAALEAVIATLR 408 Query: 395 NP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAA 453 N R+AVV GAGGDRD GKR MG A ADL++VTDDNPR EDP IR +++ GA Sbjct: 409 NQVPGRVAVVVGAGGDRDAGKRALMGEAGARGADLLIVTDDNPRTEDPAKIRASVMQGAM 468 Query: 454 E--SGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELA 511 + +V E+ DR AI AV WA+ GDVVL+AGKGHE GQ PFDDR L Sbjct: 469 DVPESERGEVREVGDRAAAIEQAVRWAQPGDVVLVAGKGHEVGQEIDGVKHPFDDREVLG 528 Query: 512 RAL 514 + Sbjct: 529 EMI 531 >tr|A4FLW5|A4FLW5_SACEN Tax_Id=405948 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Saccharopolyspora erythraea] Length = 522 Score = 402 bits (1032), Expect = e-110 Identities = 247/501 (49%), Positives = 290/501 (57%), Gaps = 15/501 (2%) Query: 20 ELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAADAIE 79 +LA +GA + P + + +TG TLRAQ V+PGDLFAAL G+ HGA AA A++ Sbjct: 5 QLAELIGARILRAPGQGPS--GRPVTGATLRAQHVRPGDLFAALPGTRVHGADFAATALD 62 Query: 80 RGAVAVLTDPAGVTAISALG---CVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXX 136 GAVAVLTD AGV L G V +LVH PR LG AAA +YG PS +L Sbjct: 63 AGAVAVLTDQAGVVRADLLDHPEVSAGRVALLVHDDPRAALGPAAAKIYGEPSKQLRILG 122 Query: 137 XXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMV 196 E T+ RI G + S TTPEAP LQA+LA MV Sbjct: 123 VTGTSGKTTTTYLLESALAAAGFTTGLVGTVETRIAGERLDSAFTTPEAPDLQALLAVMV 182 Query: 197 ERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPAS 256 E GV V MEVSSHAL LGRV G RF VGGFTNLS+DHLDFH + DYF+AKALLFD Sbjct: 183 EHGVTHVPMEVSSHALALGRVSGTRFTVGGFTNLSQDHLDFHRDLDDYFQAKALLFDG-- 240 Query: 257 ALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPAG 316 R VVC ITVS TG A W ATDV G QEFTA P G Sbjct: 241 --RSEHEVVC--TDTDWGRKLVKPGTITVSTTGD-ASWTATDVEAFPTGEQEFTAHGPGG 295 Query: 317 VGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLAL 376 + R+R+ LPG +N+AN LLA+ IL A V GL E VPGR+E+V GQDF A+ Sbjct: 296 LSLRMRLRLPGPFNIANALLAIGILHAAEVPTWAIERGLAEVDVPGRMERVALGQDFTAV 355 Query: 377 VDYAHKPGALREVLSTLR-NPQRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDN 435 VDY+HKPGA+ VL R + R+ VV G GGDRD KR MG AA + L++VTDDN Sbjct: 356 VDYSHKPGAVSAVLDAARAQAEGRVIVVLGCGGDRDVAKRPLMGEAAARRSGLLIVTDDN 415 Query: 436 PRGEDPGAIRRTIVAGAAESGGA--AQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHET 493 PR EDP IR ++AGA A +V+E DR EAI AV A +GD+V++AGKGHET Sbjct: 416 PRSEDPADIRAAMLAGAEAVPAAERGEVIERGDRREAIAEAVARASSGDIVVVAGKGHET 475 Query: 494 GQRGGAEVRPFDDRVELARAL 514 GQ V PF DR ELA AL Sbjct: 476 GQEVAGVVHPFSDREELAAAL 496 >tr|C7MV98|C7MV98_SACVD Tax_Id=471857 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase;[Saccharomonospora viridis] Length = 524 Score = 401 bits (1030), Expect = e-109 Identities = 251/517 (48%), Positives = 291/517 (56%), Gaps = 20/517 (3%) Query: 4 VESVLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAAL 63 V S RP VPL L + A L P A +V +TG TLRAQ V PGDLFAAL Sbjct: 14 VVSPPRPHLIEPVPLTTLVARADARLVADPAVAESVR---VTGATLRAQHVLPGDLFAAL 70 Query: 64 AGSATHGARHAADAIERGAVAVLTDPAGVT--AISALGCVPGTVPVLVHPAPRGVLGEAA 121 G+ HGA ADA+ GAVAVLTD G + A+ G +PVL+HP PRGVLG A Sbjct: 71 PGARAHGADFTADAVAGGAVAVLTDEEGASRPAVRESG-----LPVLIHPDPRGVLGSVA 125 Query: 122 ALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLT 181 A +YG PS L E T+ RI + S T Sbjct: 126 AWIYGEPSLTLSVLGITGTSGKTTTSYFVESGLRAAGYHTGLIGTVETRIGSERLASAFT 185 Query: 182 TPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTM 241 TPEAP LQA+ A MVERGV V MEVSSHAL LGRV+G RF VG FTNLS+DHLDFH M Sbjct: 186 TPEAPDLQALFADMVERGVTHVAMEVSSHALALGRVNGTRFTVGAFTNLSQDHLDFHRDM 245 Query: 242 ADYFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSA-TGQPAHWRATDVA 300 DYF AK+LLFD S H +VV +TVS A WRATD+ Sbjct: 246 EDYFSAKSLLFDGRST---HEIVV---VDSAWGQALVTPRTVTVSTEPDSDAGWRATDIT 299 Query: 301 PVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRV 360 G Q FT P G + + LPG +NVAN +LA AILD VGV + GL V Sbjct: 300 LTPGGEQSFTLHAPDGRKAQAVLPLPGEFNVANAVLAAAILDTVGVDLDAVLEGLATVEV 359 Query: 361 PGRLEQVDRGQDFLALVDYAHKPGALREVLSTLR-NPQRRLAVVFGAGGDRDPGKRGPMG 419 PGR+E+V GQ F A+VDYAHKP A+ + L LR + RL V G+GGDRD KR MG Sbjct: 360 PGRMERVYLGQPFTAVVDYAHKPAAVTQALRALRARTEGRLITVIGSGGDRDTAKRPMMG 419 Query: 420 RIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGA--AQVVEIADRGEAIGYAVDW 477 AA +DLV+VTDDNPR EDP AIR I+AGA G A +V+EI DR EAI AV+ Sbjct: 420 EAAARGSDLVIVTDDNPRSEDPAAIREAILAGARAVGPAEGCEVLEIGDRREAIAAAVER 479 Query: 478 ARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARAL 514 A GDVV +AGKGHE+GQ V PF DR EL A+ Sbjct: 480 AEAGDVVFVAGKGHESGQEVAGVVHPFSDRDELEAAI 516 >tr|C6WDE7|C6WDE7_ACTMD Tax_Id=446462 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Actinosynnema mirum] Length = 527 Score = 400 bits (1027), Expect = e-109 Identities = 245/510 (48%), Positives = 290/510 (56%), Gaps = 17/510 (3%) Query: 9 RPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSAT 68 RPS VP +ELA V A L A P L+TG+TLRAQ V PGDLFAAL G+ Sbjct: 28 RPSRTQSVPASELAATVDARLTS----PAGAP-VLVTGVTLRAQHVLPGDLFAALPGARA 82 Query: 69 HGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHP 128 HGA AA+A+ RGAVAVLTD G + VPVLVH PR LG +A VYG P Sbjct: 83 HGADFAAEAVRRGAVAVLTDEDGASRPELRD-----VPVLVHRDPRAALGALSARVYGEP 137 Query: 129 SDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPAL 188 + R+ E T+ RI G + S TTPEAP L Sbjct: 138 AQRVALWGVTGTSGKTTTSYMIESCLRAEGRVTGLVGTVETRIAGERLDSAFTTPEAPDL 197 Query: 189 QAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAK 248 QA+LA MVERGV VMEVSSHAL LGRV G FAVG FTNLS+DHLDFHP M DYF+AK Sbjct: 198 QALLAVMVERGVGDAVMEVSSHALRLGRVGGAGFAVGAFTNLSQDHLDFHPDMEDYFQAK 257 Query: 249 ALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQE 308 A LFD R VVC+ ++ +A A W A+ V G Q Sbjct: 258 AELFDG----RARREVVCVDGEWGRRLVKPGTVTVSATAPVGGATWTASGVRVSATGEQT 313 Query: 309 FTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVD 368 FTA P G+ V + LPG +NVAN LLA+ L A GV E GL E +VPGR+++VD Sbjct: 314 FTAHGPDGLELAVALRLPGDFNVANALLAIGCLHASGVGAEAIVRGLAEVQVPGRMQRVD 373 Query: 369 RGQDFLALVDYAHKPGALREVLSTLR-NPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 GQDF A+VDY+HKP A+ L +R R+ V G GGDRD KR MG AA ++ Sbjct: 374 VGQDFTAVVDYSHKPAAVVLALDAVRARATGRVITVLGCGGDRDTAKRPLMGAEAARRSE 433 Query: 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGA--AQVVEIADRGEAIGYAVDWARTGDVVL 485 ++VVTDDNPR EDP AIR ++AGA E A +VVEI DRG AI +AV A GDVV+ Sbjct: 434 VLVVTDDNPRSEDPAAIRAAVLAGALEVPEAERGEVVEIGDRGAAIAHAVSLAVAGDVVV 493 Query: 486 IAGKGHETGQRGGAEVRPFDDRVELARALE 515 +AGKGHETGQ V PF D L A++ Sbjct: 494 VAGKGHETGQEVAGVVHPFSDVDALTGAIQ 523 >tr|C5VD82|C5VD82_9CORY Tax_Id=553207 SubName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium matruchotii ATCC 14266] Length = 497 Score = 394 bits (1011), Expect = e-107 Identities = 240/502 (47%), Positives = 290/502 (57%), Gaps = 13/502 (2%) Query: 16 VPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAA 75 V + ++A +GA + G A VP IT + L + + G LFAA+ G+ HGAR AA Sbjct: 3 VTVLDVAQLIGARMQGGTAEQAQVP---ITEVGLNSAELPAGALFAAVPGTRVHGARFAA 59 Query: 76 DAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXX 135 D A A+LTD AG +SA G T PVLV R VLG AAA VYG PS +L Sbjct: 60 DT---AAAAILTDEAGWGLLSAAG---ETRPVLVVDDVRSVLGVAAAAVYGDPSSQLTVI 113 Query: 136 XXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAM 195 E T G +I+G +P++LTTPEAP LQA+ M Sbjct: 114 GITGTSGKTTTSYMLEAGLLAAGYRVGLIGTTGTQINGRPVPTSLTTPEAPTLQALFVQM 173 Query: 196 VERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPA 255 + GV VVMEVSSHAL LGRV G++F V GFTNLS+DHLDFH TMA+YF+AKAL F P Sbjct: 174 LAEGVTHVVMEVSSHALMLGRVLGVKFDVAGFTNLSQDHLDFHATMAEYFDAKALFFRPG 233 Query: 256 SALRGHSVVVCIXXXXXXXXXXXXXXXI-TVSATGQPAHWRATDVAPVGAGGQEFTALDP 314 S R VVC+ + T++ GQ + + V V GGQEF P Sbjct: 234 SPTRAARAVVCVDDEWGEKMASVFGSGVRTLATRGQAGDYTVSAVQTVERGGQEFRLAAP 293 Query: 315 AGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFL 374 +G + LPG +NVAN LALA+ D VGV PGL VPGR+E VD GQDFL Sbjct: 294 SGAVVAATVPLPGRFNVANAALALALADTVGVDMTALLPGLAGVGVPGRMEVVDCGQDFL 353 Query: 375 ALVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTD 433 A+VDYAHKP A++ VL+T+R R+ +V GAGGDRD KR MG AA AD VVVTD Sbjct: 354 AVVDYAHKPAAIKAVLATVRGQITGRIGLVVGAGGDRDHSKRPIMGAEAAAGADYVVVTD 413 Query: 434 DNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHET 493 DNPR EDP AIR ++AG A G+A+VVEI DR AI V WA+ GD V+IAGKGHE Sbjct: 414 DNPRNEDPAAIRAQVLAGTA--AGSAEVVEIGDRRAAIRQVVAWAKPGDAVIIAGKGHEV 471 Query: 494 GQRGGAEVRPFDDRVELARALE 515 GQ + FDDR EL ALE Sbjct: 472 GQLIDGVMHHFDDREELRAALE 493 >tr|C0E4M8|C0E4M8_9CORY Tax_Id=566549 SubName: Full=Putative uncharacterized protein;[Corynebacterium matruchotii ATCC 33806] Length = 497 Score = 392 bits (1008), Expect = e-107 Identities = 240/502 (47%), Positives = 289/502 (57%), Gaps = 13/502 (2%) Query: 16 VPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAA 75 V + ++A +GA + G A VP IT + L + + G LFAA+ G+ HGAR AA Sbjct: 3 VTVLDVAQLIGARMQGGTAEQAQVP---ITEVGLNSAELPAGALFAAVPGTRVHGARFAA 59 Query: 76 DAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXX 135 D A A+LTD AG +SA G T PVLV R VLG AAA VYG PS +L Sbjct: 60 DT---AAAAILTDEAGWGLLSAAG---ETRPVLVVDDVRSVLGVAAAAVYGDPSSQLTVI 113 Query: 136 XXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAM 195 E T G +I+G +P++LTTPEAP LQA+ M Sbjct: 114 GITGTSGKTTTSYMLEAGLLAAGYRVGLIGTTGTQINGRPVPTSLTTPEAPTLQALFVQM 173 Query: 196 VERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPA 255 + GV VVMEVSSHAL LGRV G++F V GFTNLS+DHLDFH TMA+YF+AKAL F P Sbjct: 174 LAEGVTHVVMEVSSHALMLGRVLGVKFDVAGFTNLSQDHLDFHATMAEYFDAKALFFRPG 233 Query: 256 SALRGHSVVVCIXXXXXXXXXXXXXXXI-TVSATGQPAHWRATDVAPVGAGGQEFTALDP 314 S R VVC+ + T++ GQ + + V V GGQEF P Sbjct: 234 SPTRAARAVVCVDDEWGEKMASVFGSGVRTLATRGQAGDYTVSAVQTVERGGQEFQLAAP 293 Query: 315 AGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFL 374 +G + LPG +NVAN LALA+ D VGV PGL VPGR+E VD GQDFL Sbjct: 294 SGSVVAATVPLPGRFNVANAALALALADTVGVDMTALLPGLAGVGVPGRMEVVDCGQDFL 353 Query: 375 ALVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTD 433 A+VDYAHKP A++ VL+T+R R+ +V GAGGDRD KR MG AA AD VVVTD Sbjct: 354 AVVDYAHKPAAIKAVLATVRGQITGRIGLVVGAGGDRDHSKRPIMGAEAAAGADYVVVTD 413 Query: 434 DNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHET 493 DNPR EDP AIR ++AG A G+A+VVEI DR AI V WA+ GD V+IAGKGHE Sbjct: 414 DNPRNEDPAAIRAQVLAGTA--AGSAEVVEIGDRRAAIRQVVAWAKPGDAVIIAGKGHEV 471 Query: 494 GQRGGAEVRPFDDRVELARALE 515 GQ FDDR EL ALE Sbjct: 472 GQLIDGVTHHFDDREELRAALE 493 >tr|A8KZA6|A8KZA6_FRASN Tax_Id=298653 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Frankia sp.] Length = 513 Score = 391 bits (1004), Expect = e-106 Identities = 243/515 (47%), Positives = 292/515 (56%), Gaps = 11/515 (2%) Query: 8 LRPSAGPGVPLAELAVQVGAV-LADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGS 66 LRP+A L L + ++ +A GP AA+ ++TG+T ++AV PGDL+AAL G+ Sbjct: 6 LRPAAPSPRSLTALPDVLRSITVAPGPSGGAALAGVVLTGVTHDSRAVLPGDLYAALPGA 65 Query: 67 ATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYG 126 HGA AA A+ GAVAVLTDP G A+S VP VLV PR L AAA +YG Sbjct: 66 HVHGADFAAGAVAAGAVAVLTDPVGAAALSGRLAVP----VLVTDDPRRDLAPAAAWIYG 121 Query: 127 HPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAP 186 PS L + T+ R+ G +PS TTPE+ Sbjct: 122 DPSSALTLLGVTGTNGKTTTAFLLDAGLRAAGYTTGLLGTVQTRVAGTVVPSVRTTPESG 181 Query: 187 ALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFE 246 LQA+LA MVERGV MEVSSHAL RVD +RFA FTNLS+DHLDFHPTM DYF Sbjct: 182 DLQALLATMVERGVGAASMEVSSHALAQHRVDALRFAGAAFTNLSQDHLDFHPTMEDYFA 241 Query: 247 AKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGG 306 AKA LF+PA R + VVC+ T S TG+PA W DV G GG Sbjct: 242 AKAALFEPA---RSAAAVVCVDDDWGRRLAALRPDARTYSVTGRPADWWPEDVV-AGPGG 297 Query: 307 QEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRE-TRVPGRLE 365 F AL P G + + LPG +NVAN L ALA+L AVGV E AA G+ VPGR+E Sbjct: 298 SVFRALGPDGAKADLSLALPGRFNVANALGALALLAAVGVPLEAAAEGISSLPGVPGRME 357 Query: 366 QVDRGQDFLALVDYAHKPGALREVLSTLRN-PQRRLAVVFGAGGDRDPGKRGPMGRIAAE 424 ++D GQ FLALVDYAH PGA+ +L+T+R R+ VV G GGDRD KR MG AA Sbjct: 358 RIDAGQPFLALVDYAHTPGAVETLLATVRPIVTGRVVVVLGCGGDRDRAKRPLMGAAAAR 417 Query: 425 LADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVV 484 LADL V T DNPR EDP I ++AGA + GA ++V DR AI AV A D V Sbjct: 418 LADLAVFTSDNPRSEDPARILEQMLAGARGAPGAGEIVVEPDRASAIALAVGAAGPTDAV 477 Query: 485 LIAGKGHETGQRGGAEVRPFDDRVELARALEALES 519 ++AGKGHE+GQ V PFDDR L AL A S Sbjct: 478 IVAGKGHESGQDVAGVVTPFDDREVLRSALLAAAS 512 >tr|C0XS01|C0XS01_9CORY Tax_Id=525263 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium lipophiloflavum DSM 44291] Length = 545 Score = 384 bits (987), Expect = e-104 Identities = 228/500 (45%), Positives = 278/500 (55%), Gaps = 9/500 (1%) Query: 16 VPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAA 75 VPL ELA GA +A A I+ + L A+ V PG LFAAL G+ HGA+ AA Sbjct: 17 VPLHELARIAGADVASSADNGWA--GVAISSVGLNAREVAPGGLFAALPGTRVHGAQFAA 74 Query: 76 DAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXX 135 ++ R A+LTD G+ + A G PVLV R VLGE +A VYGHPS R+ Sbjct: 75 ESPAR---AILTDREGLDIVEAAG---DRRPVLVVDDVRAVLGEVSAHVYGHPSRRMTLI 128 Query: 136 XXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAM 195 E T G RI G D+P++LTTPEAP LQA+ A M Sbjct: 129 GVTGTSGKTTTTYLLERGLIAAGAQVGLIGTTGTRIRGRDVPTSLTTPEAPTLQALFARM 188 Query: 196 VERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPA 255 GV VVMEVSSHAL+LGRVDG F GFTNLS+DHLDFHPTM DYF+AKA FDP+ Sbjct: 189 AAEGVTHVVMEVSSHALSLGRVDGTSFDAAGFTNLSQDHLDFHPTMDDYFQAKAAFFDPS 248 Query: 256 SALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPA 315 S + + VVC+ + V GQ + + V G + L Sbjct: 249 SPVAASASVVCVDDEWGERMAELASHPLRVGTHGQEGLDCSARLTAVRDNGAQDIELRID 308 Query: 316 GVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLA 375 G H + LPG +NVAN LA A+ VG Q GL VPGR+E++D GQDF+A Sbjct: 309 GQTHEFTLPLPGAFNVANAALATALARVVGADMPQFVRGLENAAVPGRMERIDAGQDFVA 368 Query: 376 LVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDD 434 +VDYAHKP A+ VL TLR R+ + GAGGDRD KR MG+ AA ADLV+VTDD Sbjct: 369 VVDYAHKPAAIAAVLETLREQVDGRIGIAVGAGGDRDTTKRAVMGQQAATRADLVIVTDD 428 Query: 435 NPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETG 494 NPR EDP AIR ++ GA E+G A++ E R EAI V WA GD +++ GKGHE G Sbjct: 429 NPRTEDPAAIRAAVLRGAREAGSGAEIRECGPRAEAIDQLVAWALPGDAIVVVGKGHEVG 488 Query: 495 QRGGAEVRPFDDRVELARAL 514 Q G FDDR E+ RAL Sbjct: 489 QIVGDTTHHFDDREEMRRAL 508 >sp|Q8NNN0|MURE_CORGL Tax_Id=1718 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Corynebacterium glutamicum] Length = 517 Score = 382 bits (982), Expect = e-104 Identities = 224/485 (46%), Positives = 280/485 (57%), Gaps = 9/485 (1%) Query: 36 AAAVPDTLITGMTLRAQAVQPGD-LFAALAGSATHGARHAADAIERGAVAVLTDPAGVTA 94 A AV + I + L + ++ D +FAA+ G+ THGA+ A AVA+LTD AG+ Sbjct: 21 AHAVGEQAIAAIGLDSSSLPTSDAIFAAVPGTRTHGAQFAGTDNAAKAVAILTDAAGLEV 80 Query: 95 ISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXX 154 ++ G T PV+V R VLG A++ +YG PS E Sbjct: 81 LNEAG---ETRPVIVVDDVRAVLGAASSSIYGDPSKDFTLIGVTGTSGKTTTSYLLEKGL 137 Query: 155 XXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGVDTVVMEVSSHALTL 214 T G RIDG ++P+ LTTPEAP LQA+ A M + GV VVMEVSSHAL+L Sbjct: 138 MEAGHKVGLIGTTGTRIDGEEVPTKLTTPEAPTLQALFARMRDHGVTHVVMEVSSHALSL 197 Query: 215 GRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRGHSVVVCIXXXXXXX 274 GRV G F V FTNLS+DHLDFHPTM DYF+AKAL F S L VVC+ Sbjct: 198 GRVAGSHFDVAAFTNLSQDHLDFHPTMDDYFDAKALFFRADSPLVADKQVVCVDDSWGQR 257 Query: 275 XXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANC 334 TVS GQ A + ATD+ +G Q F P+ ++V + LPG +NVAN Sbjct: 258 MASVAADVQTVSTLGQEADFSATDINVSDSGAQSFKINAPSNQSYQVELALPGAFNVANA 317 Query: 335 LLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLR 394 LA A VGV E A G+ + VPGR+E++D GQDFLA+VDYAHKP A+ VL TLR Sbjct: 318 TLAFAAAARVGVDGEAFARGMSKVAVPGRMERIDEGQDFLAVVDYAHKPAAVAAVLDTLR 377 Query: 395 NP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVA--- 450 RL VV GAGGDRD KRGPMG+++A+ ADLV+VTDDNPR E P IR + A Sbjct: 378 TQIDGRLGVVIGAGGDRDSTKRGPMGQLSAQRADLVIVTDDNPRSEVPATIRAAVTAGAQ 437 Query: 451 -GAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVE 509 GA+ES +V+EI DR EAI V+WA+ GD +++AGKGHE GQ FDDR E Sbjct: 438 QGASESERPVEVLEIGDRAEAIRVLVEWAQPGDGIVVAGKGHEVGQLVAGVTHHFDDREE 497 Query: 510 LARAL 514 + AL Sbjct: 498 VRAAL 502 >tr|A4QFM8|A4QFM8_CORGB Tax_Id=340322 SubName: Full=Putative uncharacterized protein;[Corynebacterium glutamicum] Length = 521 Score = 382 bits (982), Expect = e-104 Identities = 224/485 (46%), Positives = 280/485 (57%), Gaps = 9/485 (1%) Query: 36 AAAVPDTLITGMTLRAQAVQPGD-LFAALAGSATHGARHAADAIERGAVAVLTDPAGVTA 94 A AV + I + L + ++ D +FAA+ G+ THGA+ A AVA+LTD AG+ Sbjct: 25 AHAVGEQAIAAIGLDSSSLPTSDAIFAAVPGTRTHGAQFAGTDNAAKAVAILTDAAGLEV 84 Query: 95 ISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXX 154 ++ G T PV+V R VLG A++ +YG PS E Sbjct: 85 LNEAG---ETRPVIVVDDVRAVLGAASSSIYGDPSKDFTLIGVTGTSGKTTTSYLLEKGL 141 Query: 155 XXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGVDTVVMEVSSHALTL 214 T G RIDG ++P+ LTTPEAP LQA+ A M + GV VVMEVSSHAL+L Sbjct: 142 MEAGHKVGLIGTTGTRIDGEEVPTKLTTPEAPTLQALFARMRDHGVTHVVMEVSSHALSL 201 Query: 215 GRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRGHSVVVCIXXXXXXX 274 GRV G F V FTNLS+DHLDFHPTM DYF+AKAL F S L VVC+ Sbjct: 202 GRVAGSHFDVAAFTNLSQDHLDFHPTMDDYFDAKALFFRADSPLVADKQVVCVDDSWGQR 261 Query: 275 XXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANC 334 TVS GQ A + ATD+ +G Q F P+ ++V + LPG +NVAN Sbjct: 262 MASVAADVQTVSTLGQEADFSATDINVSDSGAQSFKINAPSNQSYQVELALPGAFNVANA 321 Query: 335 LLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLR 394 LA A VGV E A G+ + VPGR+E++D GQDFLA+VDYAHKP A+ VL TLR Sbjct: 322 TLAFAAAARVGVDGEAFARGMSKVAVPGRMERIDEGQDFLAVVDYAHKPAAVAAVLDTLR 381 Query: 395 NP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVA--- 450 RL VV GAGGDRD KRGPMG+++A+ ADLV+VTDDNPR E P IR + A Sbjct: 382 TQIDGRLGVVIGAGGDRDSTKRGPMGQLSAQRADLVIVTDDNPRSEVPATIRAAVTAGAQ 441 Query: 451 -GAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVE 509 GA+ES +V+EI DR EAI V+WA+ GD +++AGKGHE GQ FDDR E Sbjct: 442 QGASESERPVEVLEIGDRAEAIRVLVEWAQPGDGIVVAGKGHEVGQLVAGVTHHFDDREE 501 Query: 510 LARAL 514 + AL Sbjct: 502 VRAAL 506 >tr|C8XGZ1|C8XGZ1_NAKMY Tax_Id=479431 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Nakamurella multipartita] Length = 533 Score = 375 bits (964), Expect = e-102 Identities = 240/503 (47%), Positives = 283/503 (56%), Gaps = 14/503 (2%) Query: 18 LAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAADA 77 + E+A GA L R A + L TG+TLRAQ V+P DLFAAL GS HGA +A A Sbjct: 1 MGEVAALTGARL----ERPAPTGERL-TGITLRAQDVRPHDLFAALPGSRAHGAGYAGQA 55 Query: 78 IERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXX 137 +ERGA AVLTD AG ++ G G+V +LV PR LG A +YG PS RL Sbjct: 56 LERGAAAVLTDRAGAELLA--GTDLGSVALLVVERPREHLGAIARQLYGDPSRRLAVVGV 113 Query: 138 XXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVE 197 E T+ RIDG PS LTTPEAP LQA+LA MVE Sbjct: 114 TGTSGKTTTCYLLEAALAADGSRSAVIGTVQTRIDGQITPSALTTPEAPDLQALLAVMVE 173 Query: 198 RGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASA 257 RGV V MEVSSHAL+LGRV G RFAVG FTNLS+DHLDFH M DYF AKA+LFD Sbjct: 174 RGVGAVAMEVSSHALSLGRVSGTRFAVGAFTNLSQDHLDFHHDMEDYFRAKAMLFDG--- 230 Query: 258 LRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPAGV 317 R + V+ + +TVS A W V G Q P Sbjct: 231 -RAGAHVIDVDTEYGARLAAEHPEALTVSDRPGAADWSVEMVTLAANGVQHVVLSGPGKR 289 Query: 318 GHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALV 377 + + +PG +NV N +ALA +DA+G +QAA L VPGR+E+VD GQDFLA+V Sbjct: 290 QVTLDLAIPGAFNVGNAAVALACVDALGRDVQQAADALATVVVPGRMERVDAGQDFLAVV 349 Query: 378 DYAHKPGALREVLSTL-RNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNP 436 DYAHKPGA+ VL + + L VV GAGGDRD GKR MG +A AD+++VTDDNP Sbjct: 350 DYAHKPGAVAAVLDAIGQGLAGPLIVVLGAGGDRDTGKRPMMGAESAARADVLIVTDDNP 409 Query: 437 RGEDPGAIRRTIVAGAAESGG--AAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETG 494 R E P IR ++AGAA QV+EI DR AI AV A TG V+IAGKGHE G Sbjct: 410 RSERPADIRAQVLAGAAPVADRRPCQVLEIGDRRAAIRRAVQLAGTGGAVVIAGKGHEQG 469 Query: 495 QRGGAEVRPFDDRVELARALEAL 517 Q V PF DR EL AL AL Sbjct: 470 QEIDGVVHPFSDRDELRAALVAL 492 >tr|C3PHG1|C3PHG1_CORA7 Tax_Id=548476 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium aurimucosum] Length = 500 Score = 370 bits (949), Expect = e-100 Identities = 220/489 (44%), Positives = 275/489 (56%), Gaps = 15/489 (3%) Query: 42 TLITGMTLRAQAVQPGDLFAALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCV 101 T ++ L + A+ PG LFAAL G+ HGAR AAD A A+LTD G ++ G Sbjct: 7 TSVSSCGLNSAALPPGGLFAALPGTRVHGARFAADT---EAAAILTDAEGKRILNDAG-- 61 Query: 102 PGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXX 161 P+LV R +LG +A +Y HP+ +L E Sbjct: 62 -EKRPLLVVEDIRAILGAVSAEIYSHPTQKLTILGVTGTSGKTTTSYLLEAGLLHAGYSV 120 Query: 162 XXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIR 221 T G RI+ +P++LTTPEAP LQ + A MV GV VVMEVSSHAL+LGRV G R Sbjct: 121 GLIGTTGTRINREPVPTSLTTPEAPTLQELFARMVSEGVTHVVMEVSSHALSLGRVQGTR 180 Query: 222 FAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXX 281 F VGGFTNLS+DHLDFHPTM DYFEAKALLFD A + V Sbjct: 181 FDVGGFTNLSQDHLDFHPTMEDYFEAKALLFDGPQAADRSVICVDDEWGRRMAQRAAARP 240 Query: 282 XITVSATGQPAH----WRATDVAPVGAGGQEFTALDPAGVG-HRVRIGLPGHYNVANCLL 336 I VS T Q + R GA E T G R+ +PG +N+AN L Sbjct: 241 VIRVSTTPQGSDADITGRQLSTEVTGAQQVELTLASGEHAGTFEFRLPMPGTFNIANAAL 300 Query: 337 ALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNP 396 A + ++G+ P+ G+ + VPGR+E+VDRGQDF+A+VDYAHKP A+ VL TLR Sbjct: 301 ATGMAASIGIEPQVFLEGVEKVAVPGRMERVDRGQDFVAVVDYAHKPAAIAAVLETLRTQ 360 Query: 397 QR----RLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGA 452 R+ +V GAGGDRD KR MG AA+ ADLVVVTDDNPR EDP +IR ++AGA Sbjct: 361 LEGSAGRIGIVVGAGGDRDSSKRPLMGAAAAKGADLVVVTDDNPRTEDPASIRAAVLAGA 420 Query: 453 AESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELAR 512 E+ AA + E+ R +AI V WA+ GD V++ GKGHE GQ G V FDDR E+AR Sbjct: 421 QEANPAADIREVGSRAKAIDEVVAWAQPGDAVIVVGKGHEVGQLIGDTVHHFDDREEMAR 480 Query: 513 ALEALESCT 521 ALEA+ + T Sbjct: 481 ALEAVTTAT 489 >tr|C4LI45|C4LI45_CORK4 Tax_Id=645127 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium kroppenstedtii] Length = 526 Score = 365 bits (938), Expect = 6e-99 Identities = 227/507 (44%), Positives = 279/507 (55%), Gaps = 41/507 (8%) Query: 40 PDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALG 99 PD ++T + L AQA+ G LFA + G HGA+ A + A AVLTD GV ++ Sbjct: 21 PDLVVTDIGLNAQALPEGGLFAGVPGLHVHGAQFADSS---SAAAVLTDHDGVEKVTR-- 75 Query: 100 CVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXX 159 +P++V R VLGE ++ VY HPS L E Sbjct: 76 ---EDLPIIVVDDVRAVLGEVSSAVYDHPSRDLTVIGITGTAGKTTTSYMVEAALLHHGI 132 Query: 160 XXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDG 219 T G RI+G +PSTLTTPEAP LQA+ A M +RGV VVMEVSSHA+ LGRV G Sbjct: 133 STGLIGTTGTRINGEKVPSTLTTPEAPNLQALFAMMKKRGVTHVVMEVSSHAIALGRVLG 192 Query: 220 IRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRGHSVVVCIXXXXXXXXXXXX 279 F+V GFTNLS+DHLDFHPTM DYF+ KA LF S L + VVCI Sbjct: 193 THFSVAGFTNLSQDHLDFHPTMEDYFQTKARLFKEDSPLHAETSVVCIDDAWGQRLATML 252 Query: 280 XXXITVS--------ATGQPAHWRATDVAPVGAGGQEFTALDPAGVGH-RVRIGLPGHYN 330 TVS A+ QP W + V G + L G + I +PG +N Sbjct: 253 PHPFTVSTEAASEHDASLQPDVWAGP--SSVMDNGVQTAELYGFGANEMTLHIPMPGRFN 310 Query: 331 VANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVL 390 VAN +LA+ +L G+ E A GL VPGRLE++D GQDF+A+VDYAHKPGA+ VL Sbjct: 311 VANAMLAMGLLVKTGMKAEDAIEGLSTVTVPGRLERIDCGQDFMAVVDYAHKPGAIAAVL 370 Query: 391 STLRNPQR-RLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIV 449 TLR R R+A+V GAGGDRD KR MGR AA +DLV+VTDDNPR EDP +IR+ +V Sbjct: 371 DTLRAHVRGRIAIVVGAGGDRDHSKRPIMGREAALRSDLVIVTDDNPRSEDPASIRQQVV 430 Query: 450 AGAAE---------------------SGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAG 488 AGA E S + EI DR EAI A+ W + GD V++AG Sbjct: 431 AGAKEVADHVDVDRADEPRNKVKTEGSEHRPTIREIGDRREAIRAAIQWTQPGDAVIVAG 490 Query: 489 KGHETGQRGGAEVRPFDDRVELARALE 515 KGHETGQ G PFDDRVE R++E Sbjct: 491 KGHETGQLIGDTTHPFDDRVETRRSIE 517 >tr|C8NTK7|C8NTK7_9CORY Tax_Id=585529 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium genitalium ATCC 33030] Length = 498 Score = 365 bits (936), Expect = 1e-98 Identities = 227/508 (44%), Positives = 280/508 (55%), Gaps = 24/508 (4%) Query: 16 VPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGAR--H 73 V L LA GA + + P + +V + ++L + AV+ G +FAAL G+ HGA H Sbjct: 4 VSLENLAEIAGARVENAPESSLSV-----SAISLDSNAVKSGAMFAALPGTRVHGATFAH 58 Query: 74 AADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLX 133 A+DA AVLTD AG + G PVLV R +LG+ AA +YGHP++ L Sbjct: 59 ASDAS-----AVLTDDAGWDILRETGFER---PVLVVERVRDILGDVAAEIYGHPTEHLT 110 Query: 134 XXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLA 193 E T G RI G D+P++LTTPEAP LQ + A Sbjct: 111 VIGVTGTSGKTTTTYLLESGLTAAGCAVGLIGTTGTRIKGEDVPTSLTTPEAPKLQELFA 170 Query: 194 AMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFD 253 MV RGV VVMEVSSHAL LGRVDG +FA GFTNLS+DHLDFHPTM DYFEAKA+LFD Sbjct: 171 DMVSRGVTHVVMEVSSHALVLGRVDGTKFAAAGFTNLSQDHLDFHPTMEDYFEAKAILFD 230 Query: 254 PASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALD 313 R VVCI +TV A A + +G Q+ T + Sbjct: 231 -----RAEKAVVCIDDEWGQKMTQRAHSPVTVGVHNTSADCTARLDSVTESGAQDIT-VR 284 Query: 314 PAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDF 373 G RI LPG +N+AN LA A+ D+VG+ P+ GL RVPGR+E+V GQ F Sbjct: 285 IGGQDISTRIPLPGAFNIANTALATALADSVGIDPKVFLQGLDAARVPGRMERVSVGQPF 344 Query: 374 LALVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVT 432 +A+VDYAHKP A+ L +LR R+ VV GAGGDRD KR MG AA ADLV++T Sbjct: 345 VAVVDYAHKPAAVAAALDSLREQVDGRIGVVVGAGGDRDHSKRPLMGAEAATRADLVIIT 404 Query: 433 DDNPRGEDPGAIRRTIVAGAAE--SGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKG 490 DDNPR EDP AIR + GA G A + E+A R +AI V WA GD +++ GKG Sbjct: 405 DDNPRTEDPAAIRAAVKQGAESVIDGAATDIREVASRAQAIADLVAWAEPGDAIIVVGKG 464 Query: 491 HETGQRGGAEVRPFDDRVELARALEALE 518 HE GQ G FDDR E+A AL E Sbjct: 465 HEVGQIIGETTHHFDDREEVAFALARRE 492 >tr|B5I4K7|B5I4K7_9ACTO Tax_Id=463191 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase;[Streptomyces sviceus ATCC 29083] Length = 506 Score = 362 bits (928), Expect = 9e-98 Identities = 238/514 (46%), Positives = 283/514 (55%), Gaps = 26/514 (5%) Query: 9 RPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSAT 68 RP PLAELA Q+GA + P +AA V TG+T ++AV+PGDL+AAL G+ Sbjct: 8 RPVRVSATPLAELADQLGA---EPPQKAAQV-----TGITHDSRAVRPGDLYAALPGARL 59 Query: 69 HGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHP 128 HGA A+ GAVAVLTDP G +A G +PVLV PR +GE A +YGHP Sbjct: 60 HGADFVTQAVGLGAVAVLTDPTGAERAAATG-----LPVLVVEDPRARMGELATTIYGHP 114 Query: 129 SDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPAL 188 L E T+ +RI I S TTPEA L Sbjct: 115 GRDLLQIGITGTSGKTTTAYLVEGGLKGVRSTGLIG-TVEMRIGDERIKSERTTPEATDL 173 Query: 189 QAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAK 248 QA+ A M ERGV+ V MEVSSHAL LGRVDG F +G FTNLS +H++FH M DYF+AK Sbjct: 174 QALFAVMRERGVEAVAMEVSSHALVLGRVDGCVFDIGVFTNLSPEHMEFHSGMEDYFQAK 233 Query: 249 ALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQP-AHWRATDVAPVGAGGQ 307 A LF P + G VV +T SA G P A WRA DV VG Sbjct: 234 AQLFTPERSRLG--VVNLDDEYGRRLVKEATVPVVTFSAEGHPDADWRAADV-EVGPMDS 290 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRET-RVPGRLEQ 366 FT + P R LPG +NVAN L A+ L A G+ P+ AA G+ VPGRLE+ Sbjct: 291 TFTVIGPKDERISARSPLPGPFNVANTLAAIVALAAAGLDPQTAADGVAAVPGVPGRLER 350 Query: 367 VDRGQDFLALVDYAHKPGALREVLSTLRN-PQRRLAVVFGAGGDRDPGKRGPMGRIAAEL 425 VD GQ +LA+VDYAHK A+ VL LR + ++ +V G GGDRD KRGPMG AA L Sbjct: 351 VDAGQPYLAVVDYAHKTDAVESVLKALRKVTEGKVHIVLGCGGDRDTTKRGPMGAAAARL 410 Query: 426 ADLVVVTDDNPRGEDPGAIRRTIVAGA----AESGGAAQVVEIADRGEAIGYAVDWARTG 481 AD V+T DNPR EDP AI T++ GA A G QV E DR AI AV AR G Sbjct: 411 ADTAVLTSDNPRSEDPLAILATMLQGAASVPAHERGEVQVFE--DRAAAIAAAVARARPG 468 Query: 482 DVVLIAGKGHETGQRGGAEVRPFDDRVELARALE 515 D VL+AGKGHE GQ VRPFDDR L A++ Sbjct: 469 DTVLVAGKGHEQGQDIAGVVRPFDDRQVLREAIQ 502 >tr|Q6NGC3|Q6NGC3_CORDI Tax_Id=1717 (murE)SubName: Full=UDP-N-acetylmuramoyl-L-alanyl-D- glutamate;[Corynebacterium diphtheriae] Length = 513 Score = 360 bits (925), Expect = 2e-97 Identities = 216/481 (44%), Positives = 276/481 (57%), Gaps = 14/481 (2%) Query: 42 TLITGMTLRAQAVQPGDLFAALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCV 101 T I+ + L + + +FAAL G+ THGA +A+ A+AVL+D G + G Sbjct: 31 TEISAIGLDSSQLPADAIFAALPGTKTHGAHYASQGKAAAALAVLSDHEGTQILVDSG-- 88 Query: 102 PGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXX 161 P++ R VLG +A +YGHPS + E Sbjct: 89 -EKRPIIEVDDVRRVLGILSAEIYGHPSHEMTIIGVTGTSGKTTTSYILERGLMAAGLHV 147 Query: 162 XXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIR 221 T G RI+G +P+ LTTPEAP LQ + + M GV VVMEVSSHAL LGRV G R Sbjct: 148 GLIGTTGTRINGRKVPTKLTTPEAPTLQQLFSQMKAEGVSHVVMEVSSHALALGRVTGTR 207 Query: 222 FAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRGHSVVVCI-XXXXXXXXXXXXX 280 F+ GFTNLS+DHLDFHPTM +YFEAKAL FDPAS + VVC+ Sbjct: 208 FSAAGFTNLSQDHLDFHPTMQEYFEAKALFFDPASPIHAEKSVVCVNDLWGKNMAERAGA 267 Query: 281 XXITV-----SATGQPAHWRAT-DVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANC 334 ITV +A Q +W + DV PVGA Q F + V + LPG +N+AN Sbjct: 268 DAITVCTEQEAAAHQADYWVSNIDVNPVGA--QSF-IVHHGAQSTDVHLPLPGGFNIANT 324 Query: 335 LLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLR 394 ++ALA+ ++VGV + G+ + VPGR+E++DRGQ+FLA+VDYAHKP A+ V+ T+R Sbjct: 325 VVALALAESVGVDTDAFIRGIADVAVPGRMERIDRGQEFLAVVDYAHKPAAVAVVIDTVR 384 Query: 395 NP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAA 453 + R+AVV GAGGDRD GKR MG AA ADLV+VTDDNPR EDP IR ++ GA Sbjct: 385 DQVPGRIAVVVGAGGDRDSGKRPIMGAEAARRADLVIVTDDNPRSEDPAKIREAVLEGAH 444 Query: 454 ESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARA 513 G+A + EI DR EAI AV WA+ GD V++AGKGHE GQ FDDR E+A A Sbjct: 445 GVAGSADIREIGDRREAIRIAVQWAQPGDAVIVAGKGHEVGQLINGVDHHFDDREEVAAA 504 Query: 514 L 514 L Sbjct: 505 L 505 >tr|A0LTL8|A0LTL8_ACIC1 Tax_Id=351607 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Acidothermus cellulolyticus] Length = 522 Score = 359 bits (922), Expect = 4e-97 Identities = 239/530 (45%), Positives = 287/530 (54%), Gaps = 33/530 (6%) Query: 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 LRP+ VPLA LA A L GP A + LI G+T ++ VQPGDLFAAL G+ Sbjct: 5 LRPARVDPVPLATLAALARAELR-GP-AAGSTAGILICGVTHDSRRVQPGDLFAALPGAH 62 Query: 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 THGAR+ ADA+ GAVAVLTDPAG + I+ VP+L+ PR LG AA +YGH Sbjct: 63 THGARYVADAVTAGAVAVLTDPAGASLINR------EVPLLICADPRKTLGPVAAAIYGH 116 Query: 128 PSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPA 187 P+ L + T+ R+ +PS TTPEAP Sbjct: 117 PARALVTLGVTGTNGKTTTVFFLDAGLRAAGHRTGLLGTVMTRLGERTVPSARTTPEAPD 176 Query: 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 +QA+LA M + G+ MEVSSHAL L RVDG FA GFTNLS DHLDFH M +YF A Sbjct: 177 IQALLARMRDDGITAAAMEVSSHALALHRVDGTGFACVGFTNLSHDHLDFHGDMENYFAA 236 Query: 248 KALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAH--------WR---- 295 KA LF P A + +V+V TVS G+P H WR Sbjct: 237 KARLFRPDFAPK--AVIVVDDEYGRRLADTAPIAVRTVS--GRPEHLPPDRRPDWRVVAV 292 Query: 296 --ATDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAP 353 A V+P GQ T P G + + LPG +N+ N LLALAIL VG+ E A Sbjct: 293 RAAAAVSPTRPAGQVATVAGPIG-EVELSLQLPGRFNLTNALLALAILVEVGIPVEAARA 351 Query: 354 GLRE-TRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDP 412 G+ + VPGRLE VD GQ F LVDYAH P A+ V +R + RL +V G GGDRDP Sbjct: 352 GIGDLAGVPGRLELVDAGQPFAVLVDYAHTPEAVATVAREVRPDRGRLIIVIGCGGDRDP 411 Query: 413 GKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAG--AAESGGAAQVVEIADRGEA 470 KR MG AAELADL + T DNPR EDP I ++ G A + A++ DR EA Sbjct: 412 SKRPAMGAAAAELADLAIFTSDNPRSEDPEEIVAAMLTGVPAVTADRRAEIRVELDRHEA 471 Query: 471 IGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALESC 520 I A+ AR GDVVLIAGKGHE GQ G V PFDDR+ A +AL SC Sbjct: 472 IKDAIQAARPGDVVLIAGKGHEQGQEIGGVVHPFDDRL---AARDALRSC 518 >sp|Q8FNT5|MURE_COREF Tax_Id=152794 (murE)RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase; AltName: Full=UDP-MurNAc-tripeptide synthetase;[Corynebacterium efficiens] Length = 526 Score = 358 bits (919), Expect = 1e-96 Identities = 223/509 (43%), Positives = 273/509 (53%), Gaps = 12/509 (2%) Query: 16 VPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAA 75 + L ELA +G L + P + + + + TL +A +FAA+ GS HGA A Sbjct: 20 ITLGELARTIGGELFNAPDQDLEIHNIGLDSSTLAKKA----PIFAAVPGSRKHGAEFAD 75 Query: 76 DAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXX 135 GA+AVLTD G T + G T P L+ R VLG A++ VYG PS L Sbjct: 76 TDRAAGALAVLTDRDGATILDRKG---DTRPRLIVDDVREVLGVASSSVYGDPSRDLVLI 132 Query: 136 XXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAM 195 E T G RIDG +P+ LTTPEAP LQ + M Sbjct: 133 GVTGTSGKTTTSYLLERGLMEAGYKVGLIGTTGTRIDGEPVPTKLTTPEAPTLQKLFYRM 192 Query: 196 VERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPA 255 + GV VVMEVSSHAL+LGRV G F V FTNLS+DHLDFH TM +YF+AKAL F Sbjct: 193 RQHGVTHVVMEVSSHALSLGRVSGSHFNVAAFTNLSQDHLDFHDTMEEYFDAKALFFRAG 252 Query: 256 SALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPA 315 S L VVCI TV+ TG+ A + A V G Q FT P Sbjct: 253 SPLAADHQVVCIDDEWGTRMAEVAGNAQTVATTGKRADFTAGLVTVKETGEQSFTVTVPD 312 Query: 316 GVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLA 375 V + LPG +NVAN LALA GV P A G+ + VPGR+E++D GQDFLA Sbjct: 313 HGEVPVTLALPGAFNVANATLALAAAVRAGVDPVAFARGMAQVAVPGRMERIDEGQDFLA 372 Query: 376 LVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDD 434 +VDYAHKP A+ VL TLR RL VV GAGGDRD KR PMG ++A ADLV+VTDD Sbjct: 373 VVDYAHKPAAVAAVLDTLRTQIDGRLGVVIGAGGDRDATKRAPMGELSARRADLVIVTDD 432 Query: 435 NPRGEDPGAIRRTIV----AGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKG 490 NPR E P IR ++ GAAE+ +V EI DR EAI ++WA GD +++AGKG Sbjct: 433 NPRSEVPATIRAAVMEGARRGAAEADHEVEVREIGDRAEAIRALIEWAGPGDGIVVAGKG 492 Query: 491 HETGQRGGAEVRPFDDRVELARALEALES 519 HE GQ FDDR ++ AL +S Sbjct: 493 HEVGQLIAGVTHHFDDREQVREALRHTQS 521 >tr|C8NQ17|C8NQ17_COREF Tax_Id=196164 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium efficiens YS-314] Length = 509 Score = 358 bits (919), Expect = 1e-96 Identities = 223/509 (43%), Positives = 273/509 (53%), Gaps = 12/509 (2%) Query: 16 VPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHAA 75 + L ELA +G L + P + + + + TL +A +FAA+ GS HGA A Sbjct: 3 ITLGELARTIGGELFNAPDQDLEIHNIGLDSSTLAKKA----PIFAAVPGSRKHGAEFAD 58 Query: 76 DAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXXX 135 GA+AVLTD G T + G T P L+ R VLG A++ VYG PS L Sbjct: 59 TDRAAGALAVLTDRDGATILDRKG---DTRPRLIVDDVREVLGVASSSVYGDPSRDLVLI 115 Query: 136 XXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAAM 195 E T G RIDG +P+ LTTPEAP LQ + M Sbjct: 116 GVTGTSGKTTTSYLLERGLMEAGYKVGLIGTTGTRIDGEPVPTKLTTPEAPTLQKLFYRM 175 Query: 196 VERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPA 255 + GV VVMEVSSHAL+LGRV G F V FTNLS+DHLDFH TM +YF+AKAL F Sbjct: 176 RQHGVTHVVMEVSSHALSLGRVSGSHFNVAAFTNLSQDHLDFHDTMEEYFDAKALFFRAG 235 Query: 256 SALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPA 315 S L VVCI TV+ TG+ A + A V G Q FT P Sbjct: 236 SPLAADHQVVCIDDEWGTRMAEVAGNAQTVATTGKRADFTAGLVTVKETGEQSFTVTVPD 295 Query: 316 GVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLA 375 V + LPG +NVAN LALA GV P A G+ + VPGR+E++D GQDFLA Sbjct: 296 HGEVPVTLALPGAFNVANATLALAAAVRAGVDPVAFARGMAQVAVPGRMERIDEGQDFLA 355 Query: 376 LVDYAHKPGALREVLSTLRNP-QRRLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDD 434 +VDYAHKP A+ VL TLR RL VV GAGGDRD KR PMG ++A ADLV+VTDD Sbjct: 356 VVDYAHKPAAVAAVLDTLRTQIDGRLGVVIGAGGDRDATKRAPMGELSARRADLVIVTDD 415 Query: 435 NPRGEDPGAIRRTIV----AGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKG 490 NPR E P IR ++ GAAE+ +V EI DR EAI ++WA GD +++AGKG Sbjct: 416 NPRSEVPATIRAAVMEGARRGAAEADHEVEVREIGDRAEAIRALIEWAGPGDGIVVAGKG 475 Query: 491 HETGQRGGAEVRPFDDRVELARALEALES 519 HE GQ FDDR ++ AL +S Sbjct: 476 HEVGQLIAGVTHHFDDREQVREALRHTQS 504 >tr|D1A7V1|D1A7V1_THECU Tax_Id=471852 SubName: Full=UDP-N-acetylmuramyl-tripeptide synthetase;[Thermomonospora curvata DSM 43183] Length = 515 Score = 358 bits (918), Expect = 1e-96 Identities = 238/512 (46%), Positives = 285/512 (55%), Gaps = 19/512 (3%) Query: 7 VLRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGS 66 ++RP+ P PL L V++ + ADGP A +TG+T ++ V PGDL+ AL G+ Sbjct: 1 MMRPTTNPARPLLGL-VELLSAQADGPGLAKVA----VTGITHDSRQVLPGDLYVALPGT 55 Query: 67 ATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYG 126 HGA AA A GAVA+ TDPAG +A G +PVLV R LGEAA+ VYG Sbjct: 56 RAHGAEFAAQAAAAGAVAIWTDPAGRHRAAATG-----LPVLVTDDVRARLGEAASWVYG 110 Query: 127 HPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAP 186 P+ L E T+ +RI +PS+LTTPEA Sbjct: 111 DPARDLSLIGVTGTSGKTTTVYLLEAGLRAAGVDTAVIGTVEMRIGDTRLPSSLTTPEAT 170 Query: 187 ALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFE 246 L A+ A M E GV MEVSSHAL GRV G + V FTNLS+DHLD+H TMADYF Sbjct: 171 DLHAIFAKMREVGVGAAAMEVSSHALAQGRVGGTCYDVAVFTNLSQDHLDYHATMADYFA 230 Query: 247 AKALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATGQP-AHWRATDVAPVGAG 305 AKA LF PA + G VV T SA G P A WRA DV +GA Sbjct: 231 AKAKLFTPAYSRVG--VVNVDDGYGRELTRIAQVPLTTFSAAGDPSADWRAEDVR-LGAD 287 Query: 306 GQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRE-TRVPGRL 364 G F + P G+ V I LPG +NVAN L A+ L G+ + AA G+ T VPGRL Sbjct: 288 GSVFRLVGPGGIEADVSIQLPGPFNVANALAAIVALVEAGLPLQVAAAGVGTLTGVPGRL 347 Query: 365 EQVDRGQDFLALVDYAHKPGALREVLSTLRN-PQRRLAVVFGAGGDRDPGKRGPMGRIAA 423 E +D GQDF ALVDY+HKPGA+ VL++LR RL VV G GGDRD GKR MG AA Sbjct: 348 EPIDEGQDFTALVDYSHKPGAVEAVLTSLREVTAGRLIVVLGCGGDRDRGKRPLMGETAA 407 Query: 424 ELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGA--AQVVEIADRGEAIGYAVDWARTG 481 LAD+ V+TDDNPR EDP AI +V G + A A +V DR AI A+ AR G Sbjct: 408 RLADVAVLTDDNPRSEDPLAILAAMVEGVLKVPQAERAHLVVEPDRAAAIALALGRARRG 467 Query: 482 DVVLIAGKGHETGQRGGAEVRPFDDRVELARA 513 DVV+IAGKGHE GQ V PFDDR E+ RA Sbjct: 468 DVVVIAGKGHEQGQYVAGRVLPFDDR-EVVRA 498 >tr|B1VHC9|B1VHC9_CORU7 Tax_Id=504474 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium urealyticum] Length = 533 Score = 357 bits (916), Expect = 2e-96 Identities = 230/519 (44%), Positives = 284/519 (54%), Gaps = 34/519 (6%) Query: 15 GVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSATHGARHA 74 GV L ELA G +A A D + + + VQPG LF A+ GS HGA A Sbjct: 16 GVTLRELAALTGGTVA------ATHQDVTVDSAAIGSADVQPGGLFCAVPGSRVHGATFA 69 Query: 75 ADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHPSDRLXX 134 AD+ GA AVLTD G ++ +P+LV R +G AA VYGHPS L Sbjct: 70 ADS---GAAAVLTDAEGAEILA-----DADLPLLVVDDVRRWMGPVAAAVYGHPSRDLRI 121 Query: 135 XXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPALQAMLAA 194 E T G RI+G IP+ LTTPEAP +QA+LA Sbjct: 122 IGITGTSGKTTTTYLIERALMAKHSVGIIGTT-GTRINGEQIPTKLTTPEAPTMQALLAQ 180 Query: 195 MVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDP 254 M +RGV VVMEVSSHAL LGRV GI F V GFTNLS+DHLDFHPTM DYFE KA LF Sbjct: 181 MRDRGVTHVVMEVSSHALALGRVTGIDFDVAGFTNLSQDHLDFHPTMEDYFETKAQLFLQ 240 Query: 255 ASALRGH--SVVVCI----XXXXXXXXXXXXXXXITVSATGQP-AHWRATDVAPVGAGGQ 307 A A + VVC+ +TV T Q A W+ TDV AG Q Sbjct: 241 AQAEGAELPAAVVCVDDDWGQRLAGMIADSGLQALTVGTTKQSGADWQVTDVHVTPAGRQ 300 Query: 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 E T + G IGL G +NVAN LLA++ + +G P+ AA + + +VPGR++ V Sbjct: 301 EIT-VATEGEEFSYDIGLVGSFNVANSLLAISCVTQLGEDPQAAAAAIADVQVPGRMQAV 359 Query: 368 DRGQDFLALVDYAHKPGALREVLSTLR----NPQRRLAVVFGAGGDRDPGKRGPMGRIAA 423 D GQ FLA+VDYAHKPGA+ V+ TL +P R+ +V GAGG+RD KR MG AA Sbjct: 360 DAGQPFLAVVDYAHKPGAVAAVVRTLSDYLPSPTGRIGIVLGAGGNRDHDKRPMMGEEAA 419 Query: 424 ELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQV-------VEIADRGEAIGYAVD 476 ++AD V VTDDNPR E+P IR I+ G ++ A + ++ R +AI AV Sbjct: 420 KVADAVFVTDDNPRDEEPAPIRSMILDGVRKAAEAREANGEKVFYDDVPGRADAIRAAVA 479 Query: 477 WARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALE 515 WAR GD +++AGKGHETGQ E+ PF D ELA ALE Sbjct: 480 WARPGDAIVVAGKGHETGQEVRGEIHPFADLEELAAALE 518 >tr|C2BNI4|C2BNI4_9CORY Tax_Id=525264 (murE)SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Corynebacterium pseudogenitalium ATCC 33035] Length = 511 Score = 357 bits (915), Expect = 3e-96 Identities = 214/479 (44%), Positives = 260/479 (54%), Gaps = 17/479 (3%) Query: 44 ITGMTLRAQAVQPGDLFAALAGSATHGARHAADAIERGAVAVLTDPAGVTAISALGCVPG 103 ++ L + + G LFAAL G+ HGA+ A D A AVLTD AG+ ++ Sbjct: 24 VSACGLDSSRLPEGALFAALPGTRVHGAQFARDT---KAGAVLTDAAGLDLLTE---AQE 77 Query: 104 TVPVLVHPAPRGVLGEAAALVYGHPSDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXX 163 T P+LV R VLG +A +YGHP+ L E Sbjct: 78 TRPILVVEDIRAVLGPISAEIYGHPTRELTVIGVTGTSGKTTTSYLLEAGLLHAGHSVGL 137 Query: 164 XXTIGIRIDGADIPSTLTTPEAPALQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFA 223 T G RI+ +P++LTTPEAP LQ + A M GV VVMEVSSHAL LGRV G RFA Sbjct: 138 IGTTGTRINRTPVPTSLTTPEAPTLQELFARMKNEGVTHVVMEVSSHALELGRVRGTRFA 197 Query: 224 VGGFTNLSRDHLDFHPTMADYFEAKALLFDPASALRGHSVVVCI----XXXXXXXXXXXX 279 VGGFTNLS+DHLDFHPTM DYF+AKA LF A V+CI Sbjct: 198 VGGFTNLSQDHLDFHPTMEDYFQAKAKLF--AGEQAAERAVLCIDDEWGERMRGVAKSAG 255 Query: 280 XXXITVSATGQPAHWRATDVAPVGAGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALA 339 TV G A A A G QE ALD G R+ LPG +N+AN LAL Sbjct: 256 HEVTTVDTQGAAATISARQTATEATGAQE-VALDYDGANFTFRLPLPGEFNIANACLALG 314 Query: 340 ILDAVGVSPEQAAPGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQR- 398 + AVG P + G+ + VPGR+E++DRGQDF+A+VDYAHKP A+ VL TLR Sbjct: 315 MATAVGEDPAEFLSGVEKVAVPGRMERIDRGQDFVAVVDYAHKPAAIAAVLDTLRGQLEG 374 Query: 399 ---RLAVVFGAGGDRDPGKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAES 455 R+ +V GAGGDRD KR MG AA ADL VVTDDNPR EDP IR +V GA ++ Sbjct: 375 TTGRVGIVVGAGGDRDSSKRPIMGAAAASRADLTVVTDDNPRSEDPATIRAAVVEGARDA 434 Query: 456 GGAAQVVEIADRGEAIGYAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARAL 514 + E+ R AI VDWA GD V++ GKGHE GQ + FDDR E+ARA+ Sbjct: 435 APQGDIREVGSRARAIDEVVDWAEPGDAVIVVGKGHEVGQLVNGKTLHFDDREEMARAI 493 >tr|A1SL85|A1SL85_NOCSJ Tax_Id=196162 SubName: Full=UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; EC=6.3.2.13;[Nocardioides sp.] Length = 504 Score = 355 bits (911), Expect = 8e-96 Identities = 227/520 (43%), Positives = 278/520 (53%), Gaps = 30/520 (5%) Query: 9 RPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSAT 68 RP+ P PLA +A GA L P ++G++L +Q ++PGDL+AAL GS Sbjct: 7 RPAQPPRTPLATVAAWAGAELRGNPAGLE------VSGISLSSQRIRPGDLYAALPGSRA 60 Query: 69 HGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGHP 128 HG A DA+ GAVAV TD AG P P LV PR VLG +A +YG P Sbjct: 61 HGIEFAQDALAAGAVAVFTDEAGADR------GPAGAPHLVVDRPRAVLGRLSARIYGEP 114 Query: 129 SDRLXXXXXXXXXXXXXXXXXXEXXXXXXXXXXXXXXTIGIRIDGADIPSTLTTPEAPAL 188 + + E T+G RI G ++ S+LTTPEAP L Sbjct: 115 AASMRMVGVTGTQGKTTTTRLLEAGLQQAGVPAAVVGTVGTRIAGEEVRSSLTTPEAPDL 174 Query: 189 QAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEAK 248 A+ A M ER V MEVSSHAL +GRVDG+ F V F NL RDHLDFH + DY+ AK Sbjct: 175 HALFAVMRERDVRACAMEVSSHALVMGRVDGVVFDVAVFLNLGRDHLDFHRDLEDYYAAK 234 Query: 249 ALLFDPASALRGHSVVVCIXXXXXXXXXXXXXXXITVSATG-----QPAHWRATDVAPVG 303 A LF P R +V + + + G Q A WRA DV + Sbjct: 235 ASLFTPE---RARFALVNVDDAHGRRLAEEATVPVRTFSMGRGDDAQRADWRAVDVR-LR 290 Query: 304 AGGQEFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRET-RVPG 362 A G EF + P G LPG +NVAN L A+A G+ P A G+ VPG Sbjct: 291 ATGSEFVVVAPDGRRIPAGCALPGDFNVANTLAAVAAAAEAGLDPAVVAAGIAAAGGVPG 350 Query: 363 RLEQVDRGQDFLALVDYAHKPGALREVLSTLRN-PQRRLAVVFGAGGDRDPGKRGPMGRI 421 RLE+VD GQDFL +VDYAHKP A+ + TLR + R+ VV GAGGDRDPGKR M I Sbjct: 351 RLERVDAGQDFLVVVDYAHKPDAVEAAIRTLRPLTEGRVIVVLGAGGDRDPGKRPIMAGI 410 Query: 422 AAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTG 481 AA LADL+VVTDDNPR EDP AIR ++AG Q +E+ R AI A+ A G Sbjct: 411 AARLADLLVVTDDNPRTEDPAAIRAAMLAGVV----TGQAIEVGGRRAAIREALRRAGPG 466 Query: 482 DVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALESCT 521 D+VLIAGKGHETGQ V PFDDR E+ R E + +C+ Sbjct: 467 DIVLIAGKGHETGQEVDGVVHPFDDR-EVVR--EEIVACS 503 Database: Amellifera_nr Posted date: Feb 5, 2010 5:10 AM Number of letters in database: 3,846,993,858 Number of sequences in database: 11,275,203 Lambda K H 0.319 0.136 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 11275203 Number of Hits to DB: 3,653,856,417 Number of extensions: 149688859 Number of successful extensions: 452698 Number of sequences better than 10.0: 5014 Number of HSP's gapped: 449902 Number of HSP's successfully gapped: 6517 Length of query: 521 Length of database: 3,846,993,858 Length adjustment: 142 Effective length of query: 379 Effective length of database: 2,245,915,032 Effective search space: 851201797128 Effective search space used: 851201797128 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 83 (36.6 bits)